Guide to the Human Genome
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Name: ZAP70 Sequence: fasta or formatted (312aa) NCBI GI: 46488944
Description:

zeta-chain associated protein kinase 70kDa isoform 2

Referenced in:

Dual-Specificity Phosphatases
Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt prot [619aa] zeta-chain associated protein kinase 70kDa isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.0         25           2
 C cysteine            2.6          8           1
 D aspartate           5.1         16           2
 E glutamate           8.3         26           2
 F phenylalanine       2.9          9           1
 G glycine             6.4         20           3
 H histidine           1.6          5           1
 I isoleucine          3.8         12           1
 K lysine              8.3         26           2
 L leucine             8.7         27           2
 M methionine          5.4         17           2
 N asparagine          2.6          8           1
 P proline             5.4         17           2
 Q glutamine           3.5         11           1
 R arginine            5.4         17           1
 S serine              6.1         19           2
 T threonine           2.2          7           1
 V valine              6.4         20           1
 W tryptophan          1.9          6           1
 Y tyrosine            5.1         16           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   zeta-chain associated protein kinase 70kDa isoform 2... 
ZAP70                 1.000   zeta-chain associated protein kinase 70kDa isoform 1...
SYK                   0.579   spleen tyrosine kinase isoform 2 
SYK                   0.579   spleen tyrosine kinase isoform 1 
PTK2                  0.309   PTK2 protein tyrosine kinase 2 isoform b 
PTK2                  0.309   PTK2 protein tyrosine kinase 2 isoform a 
EPHA3                 0.296   ephrin receptor EphA3 isoform a precursor 
EPHB1                 0.296   ephrin receptor EphB1 precursor 
EPHA5                 0.293   ephrin receptor EphA5 isoform b precursor 
EPHA5                 0.293   ephrin receptor EphA5 isoform a precursor 
EPHB2                 0.291   ephrin receptor EphB2 isoform 1 precursor 
EPHB2                 0.291   ephrin receptor EphB2 isoform 2 precursor 
EPHA2                 0.290   ephrin receptor EphA2 
EPHB4                 0.286   EPH receptor B4 precursor 
FER                   0.286   fer (fps/fes related) tyrosine kinase 
EPHB3                 0.286   ephrin receptor EphB3 precursor 
ERBB4                 0.285   v-erb-a erythroblastic leukemia viral oncogene homo...
ERBB4                 0.285   v-erb-a erythroblastic leukemia viral oncogene homolo...
EPHA7                 0.285   ephrin receptor EphA7 
EPHA4                 0.283   ephrin receptor EphA4 
ABL2                  0.282   arg tyrosine kinase isoform c 
ABL2                  0.282   arg tyrosine kinase isoform b 
ABL2                  0.282   arg tyrosine kinase isoform e 
ABL2                  0.282   arg tyrosine kinase isoform d 
ABL2                  0.282   arg tyrosine kinase isoform a 
ABL1                  0.278   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL1                  0.278   c-abl oncogene 1, receptor tyrosine kinase isoform b...
PTK2B                 0.278   PTK2B protein tyrosine kinase 2 beta isoform a [Homo...
PTK2B                 0.278   PTK2B protein tyrosine kinase 2 beta isoform b [Homo...
PTK2B                 0.278   PTK2B protein tyrosine kinase 2 beta isoform a [Homo...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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