Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 4557509
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557509 cylicin 2 [Homo sapiens]
(348 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557509 cylicin 2 [Homo sapiens] 689 0.0
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 178 6e-45
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 87 2e-17
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 86 6e-17
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 84 2e-16
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 84 2e-16
gi|104526627 triadin [Homo sapiens] 83 4e-16
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 82 9e-16
gi|157738619 smoothelin-like 1 [Homo sapiens] 80 3e-15
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 79 8e-15
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 79 8e-15
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 78 1e-14
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 78 1e-14
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 78 1e-14
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 78 1e-14
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 78 1e-14
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 77 2e-14
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 77 2e-14
gi|11225260 DNA topoisomerase I [Homo sapiens] 77 2e-14
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 76 4e-14
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 75 7e-14
gi|112380630 leiomodin 1 (smooth muscle) [Homo sapiens] 75 1e-13
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 74 3e-13
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 73 3e-13
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 72 6e-13
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 72 7e-13
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi... 72 7e-13
gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo... 72 1e-12
gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo ... 72 1e-12
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 72 1e-12
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 689 bits (1778), Expect = 0.0
Identities = 348/348 (100%), Positives = 348/348 (100%)
Query: 1 MSLPRFQRVNFGPYDNYIPVSELSKKSWNQQHFALLFPKPQRPGTKRRSKPSQIRDNTVS 60
MSLPRFQRVNFGPYDNYIPVSELSKKSWNQQHFALLFPKPQRPGTKRRSKPSQIRDNTVS
Sbjct: 1 MSLPRFQRVNFGPYDNYIPVSELSKKSWNQQHFALLFPKPQRPGTKRRSKPSQIRDNTVS 60
Query: 61 IIDEEQLRGDRRQPLWMYRSLMRISERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGED 120
IIDEEQLRGDRRQPLWMYRSLMRISERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGED
Sbjct: 61 IIDEEQLRGDRRQPLWMYRSLMRISERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGED 120
Query: 121 KTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESED 180
KTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESED
Sbjct: 121 KTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESED 180
Query: 181 EKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKAD 240
EKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKAD
Sbjct: 181 EKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKAD 240
Query: 241 EKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDA 300
EKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDA
Sbjct: 241 EKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDA 300
Query: 301 KKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
KKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK
Sbjct: 301 KKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 178 bits (452), Expect = 6e-45
Identities = 136/406 (33%), Positives = 200/406 (49%), Gaps = 65/406 (16%)
Query: 1 MSLPRFQRVNFGPYDNYIPVSELSKKSWNQQHFALLFPKPQRPGTKRRSKP--SQIRDNT 58
MSLPR +VN YDN IP+SE S+KSWNQ+HFAL FPKP + GT +S+P SQI T
Sbjct: 1 MSLPRLLKVNIRTYDNSIPISESSRKSWNQKHFALTFPKPLQRGTNDKSRPLKSQI---T 57
Query: 59 VSIIDEEQL-RGDRRQPLWMYRSLMRISERPSVYLAARRQ-PLKPTRTVEVDSKAAEIGK 116
V+ D+ +L G + W+ S +I + P +Y AAR Q P + T + K AE K
Sbjct: 58 VTRHDKRKLEEGQKPAHKWIRHSFRKILQWPPIYTAAREQTPFRHLYTSKTHLKKAEYKK 117
Query: 117 KGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSAT 176
++K DS+ + + + + +E+ + + +A K K + E+ K S +
Sbjct: 118 SKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKS 177
Query: 177 ------ESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSK----- 225
ES++ K +K ++KDKKDS K + TE K +KD K+ K +
Sbjct: 178 SSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEI 237
Query: 226 ---------------KGKDSAIELQA--------------------VKADEKKDEDGKKD 250
+ D +I A K D KK+ D
Sbjct: 238 CSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSD 297
Query: 251 ANKGDESKDAKKDAKEIKKG--KKDKKKPSSTDSDSKD-------DVKKESKKDATKDAK 301
A + ++SKDAKKD+K++KK K DKKK D++S D D +K++KKD K K
Sbjct: 298 A-ESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKK 356
Query: 302 KVAKKDTEK--ESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKK 345
KKDT+K ES D++ K+A+ D++ K + D+KKDAKK
Sbjct: 357 DDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKK 402
Score = 123 bits (309), Expect = 2e-28
Identities = 100/258 (38%), Positives = 133/258 (51%), Gaps = 49/258 (18%)
Query: 117 KGEDKTTQKDTTDSESE-LKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSA 175
K + K K ++D+ESE K KKDSKK K K ++K D KKD++ DAE G
Sbjct: 285 KKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTE--STDAESG---- 338
Query: 176 TESEDEKGGAKKDNKKDKKDSNK----------------GKDSATESEGEKGGTEKDSKK 219
+S+DE+ KKD KK KKD K KD+ +S K ++ D K
Sbjct: 339 -DSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDK- 396
Query: 220 GKKDSKK-----GKDSAIELQAVKADEKKDE-----DGKKDANKGDESKDAKKDAK-EIK 268
KKD+KK +S +E + + DEKKD+ D KK +ES DA + K + K
Sbjct: 397 -KKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSK 455
Query: 269 KGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAK-KNAKKDA 327
KGKKD+KK K D KK+ KK KDAKK A+ + + KKD K KK +
Sbjct: 456 KGKKDEKK-------GKKDSKKDDKK---KDAKKNAESTEMESDLELKKDKKHSKEKKGS 505
Query: 328 KKDAKKNAKKD-EKKDAK 344
KKD KK+A+KD E DA+
Sbjct: 506 KKDIKKDARKDTESTDAE 523
Score = 122 bits (305), Expect = 6e-28
Identities = 103/284 (36%), Positives = 136/284 (47%), Gaps = 57/284 (20%)
Query: 94 ARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEE 153
A++ K + V+ D K ++ K E +T ++ DS+ E K KKD KK K +K K+
Sbjct: 306 AKKDSKKVKKNVKKDDKKKDVKKDTE--STDAESGDSKDERKDTKKDKKKLKKDDKKKDT 363
Query: 154 KL-------------DAKKDS---KKGKKDAEKGKDSA-------TESEDEKGGAKKDNK 190
K DA+ DS KK K+ +K KD+ +ESE E ++KD K
Sbjct: 364 KKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEK 423
Query: 191 KDKKDSN-------KGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKK 243
KDKKDS K + +T+++ E G DSKKGKKD KKGK D KK
Sbjct: 424 KDKKDSKTDNKKSVKNDEESTDADSEPKG---DSKKGKKDEKKGKK----------DSKK 470
Query: 244 DEDGKKDANKGDES---------KDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKK 294
D D KKDA K ES K KK +KE K KKD KK + D++S D ES K
Sbjct: 471 D-DKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSK 529
Query: 295 DATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKD 338
K + K+ DTE E + K AKK K D N+K +
Sbjct: 530 TGFKTSTKIKGSDTESEESLYKPGAKK--KIDESDGTSANSKME 571
Score = 106 bits (265), Expect = 3e-23
Identities = 85/259 (32%), Positives = 121/259 (46%), Gaps = 23/259 (8%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKK- 166
DSK A+ K K +KD + + D++ G ++ K+ K D KK K KK
Sbjct: 302 DSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKK 361
Query: 167 ---------DAEKG--KDSATESEDEKGGAKKDNKKDKKDSNKGKDSA-TESEGEKGGTE 214
D E G KD+ +S + K +K D+K KKD+ K S +ESE E ++
Sbjct: 362 DTKKYPESTDTESGDAKDARNDSRNLKKASKNDDK--KKDAKKITFSTDSESELESKESQ 419
Query: 215 KDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDK 274
KD KK KKDSK +++ D + G K DE K KKD+K+ K K K
Sbjct: 420 KDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKK-GKKDSKKDDKKKDAK 478
Query: 275 KKPSSTDSDSKDDVKKE-----SKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKK 329
K ST+ +S ++KK+ KK + KD KK A+KDTE A+ + +K K K
Sbjct: 479 KNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKI 538
Query: 330 DAKKNAKKDE--KKDAKKK 346
++ K AKKK
Sbjct: 539 KGSDTESEESLYKPGAKKK 557
Score = 92.8 bits (229), Expect = 4e-19
Identities = 77/250 (30%), Positives = 122/250 (48%), Gaps = 37/250 (14%)
Query: 108 DSKAAEIGKKGEDKTTQKD------TTDSESEL--KQGKKDSKKGKDIEKGKEEKLDAKK 159
DS+ + K +DK +KD +TDSESEL K+ +KD KK +K D+K
Sbjct: 383 DSRNLKKASKNDDK--KKDAKKITFSTDSESELESKESQKDEKK---------DKKDSKT 431
Query: 160 DSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKG---KDSATESEGEKGGTEKD 216
D+KK K+ E+ D+ +E + + KKD KK KKDS K KD+ +E + ++ +
Sbjct: 432 DNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLE 491
Query: 217 SKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKK 276
KK KK SK+ K S +D KKDA K ES DA+ D + K G K K
Sbjct: 492 LKKDKKHSKEKKGS-------------KKDIKKDARKDTESTDAEFD-ESSKTGFKTSTK 537
Query: 277 PSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAK 336
+D++S++ + K K D +++ E +SK+ + ++KK + + A
Sbjct: 538 IKGSDTESEESLYKPGAKKKI-DESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKAS 596
Query: 337 KDEKKDAKKK 346
+++K
Sbjct: 597 TGRVPPSREK 606
Score = 45.8 bits (107), Expect = 6e-05
Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 256 ESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADS 315
+SKD +K +KK K K +T+ +SK V++++K+ D + ++S S
Sbjct: 117 KSKD-EKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKS 175
Query: 316 KKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
K ++ N + K KN + +KKD+K K
Sbjct: 176 KSSSETNPESQNSKTVSKNCSQKDKKDSKNSKK 208
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 87.0 bits (214), Expect = 2e-17
Identities = 54/207 (26%), Positives = 113/207 (54%), Gaps = 7/207 (3%)
Query: 142 KKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKD 201
++ ++IE KE K + + + KK +++ EK K E E ++ KK+ K ++K + +
Sbjct: 40 EREREIETRKEGKKERESERKKERREREKRKRER-EKERKRERGKKEKKGERKKEERERK 98
Query: 202 SATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAK 261
+ K G EK+ +K K+ ++G+ S + + +E+K E+ +K+ + E ++ +
Sbjct: 99 KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE-RKERERKKEEREKE 157
Query: 262 KDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKK 321
++ KE K K+++K+ + + K+ +KE KK ++ K+ K+ KE + KK+ KK
Sbjct: 158 RERKERK--KRERKQVGEKEEERKEKERKERKK-RERNRKERKKERERKERRERKKERKK 214
Query: 322 --NAKKDAKKDAKKNAKKDEKKDAKKK 346
KK+ +KD + N ++ E+ ++K
Sbjct: 215 KEERKKERQKDRQTNWREKERGKRERK 241
Score = 79.3 bits (194), Expect = 5e-15
Identities = 60/233 (25%), Positives = 121/233 (51%), Gaps = 31/233 (13%)
Query: 116 KKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKG--KKDAEKGKD 173
++ E +T ++ + ESE K+ +++ +K K E+ KE K + K KKG KK+ + K
Sbjct: 41 REREIETRKEGKKERESERKKERREREKRKR-EREKERKRERGKKEKKGERKKEERERKK 99
Query: 174 SATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIE 233
E E+++G K+ KK +K E+G T K+ K+ ++ ++ ++ E
Sbjct: 100 RRREKENKEGEEKEKRKKKEKK-------------ERGRTSKEGKERERKEERKREERKE 146
Query: 234 LQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESK 293
+ K +E++ E +K+ K + + +K+ + +K +K++KK ++ +KE K
Sbjct: 147 RER-KKEEREKERERKERKKRERKQVGEKEEERKEKERKERKK--------RERNRKERK 197
Query: 294 KDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKD-AKKNAKKDEKKDAKK 345
K+ + ++ KK+ +K K++ KK +KD + + +K K E+K+ KK
Sbjct: 198 KERERKERRERKKERKK-----KEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 71.2 bits (173), Expect = 1e-12
Identities = 50/199 (25%), Positives = 101/199 (50%), Gaps = 9/199 (4%)
Query: 102 TRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDS 161
TR + +E K+ ++ +K + E + ++GKK+ K + E+ + +K +K++
Sbjct: 47 TRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKEN 106
Query: 162 KKGK-KDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKG 220
K+G+ K+ K K+ K G +++ K+++K + + + E EK E++ K+
Sbjct: 107 KEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK---ERERKER 163
Query: 221 KKDSKK--GKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKK---GKKDKK 275
KK +K G+ + + + KK E +K+ K E K+ ++ KE KK KK+++
Sbjct: 164 KKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQ 223
Query: 276 KPSSTDSDSKDDVKKESKK 294
K T+ K+ K+E K+
Sbjct: 224 KDRQTNWREKERGKRERKE 242
Score = 70.5 bits (171), Expect = 2e-12
Identities = 54/222 (24%), Positives = 115/222 (51%), Gaps = 22/222 (9%)
Query: 103 RTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKK--GKDIEKG---KEEKLDA 157
R E + + + GKK + +K+ + E ++ +K+ K+ GK +KG KEE+
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
Query: 158 KKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDS 217
K+ +K K+ E+ + + + E+G K+ K+ ++ + ++ E E +K E++
Sbjct: 99 KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK--EEREK 156
Query: 218 KKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKK--DAKEIKKGKKDKK 275
++ +K+ KK + + K +E+K+++ K+ + K+ KK + KE ++ KK++K
Sbjct: 157 ERERKERKKRERKQV---GEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK 213
Query: 276 KPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKK 317
K K++ KKE +KD + ++ K+ ++E + KK
Sbjct: 214 K--------KEERKKERQKDRQTNWRE--KERGKRERKERKK 245
Score = 69.3 bits (168), Expect = 5e-12
Identities = 54/198 (27%), Positives = 105/198 (53%), Gaps = 16/198 (8%)
Query: 86 ERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGK 145
ER S RR+ K R E + K E GKK +K ++ + E + ++ +K++K+G+
Sbjct: 54 ERESERKKERREREKRKREREKERKR-ERGKK--EKKGERKKEERERKKRRREKENKEGE 110
Query: 146 DIEKGKE-EKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKD------SNK 198
+ EK K+ EK + + SK+GK E+ + + E+ K +++ KK++++ K
Sbjct: 111 EKEKRKKKEKKERGRTSKEGK---ERERKEERKREERK---ERERKKEEREKERERKERK 164
Query: 199 GKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESK 258
++ E E+ EK+ K+ KK + K+ E + + E+K E KK+ K + K
Sbjct: 165 KRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQK 224
Query: 259 DAKKDAKEIKKGKKDKKK 276
D + + +E ++GK+++K+
Sbjct: 225 DRQTNWREKERGKRERKE 242
Score = 33.9 bits (76), Expect = 0.22
Identities = 16/73 (21%), Positives = 38/73 (52%)
Query: 276 KPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNA 335
KP + + ++E + + K+ KK + + +KE + +K ++ K+ ++ KK
Sbjct: 27 KPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEK 86
Query: 336 KKDEKKDAKKKGK 348
K + KK+ +++ K
Sbjct: 87 KGERKKEERERKK 99
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 85.5 bits (210), Expect = 6e-17
Identities = 71/265 (26%), Positives = 123/265 (46%), Gaps = 26/265 (9%)
Query: 99 LKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAK 158
+KPT E + + + KKG+ Q + EL+ KDSK K K K E
Sbjct: 81 VKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELED--KDSKS-KKTAKPKVEMYSGS 137
Query: 159 KDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSK 218
D K +K K A +S + G+++D KK + + +++ G++ S+
Sbjct: 138 DDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSR 197
Query: 219 KGKKDSKKGK------------DSAIELQAV---KADEKKDEDGKKDANKGDESKDAKKD 263
KG+K ++K K D++ +++ V KA++K+ E K+D K K K+
Sbjct: 198 KGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRK--LKE 255
Query: 264 AKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNA 323
+E++ GKKD+ K + +++ K T D + + + E+ + +D +
Sbjct: 256 KEELETGKKDQSKQKESQRKFEEETVKSK---VTVDTGVIPASEEKAETPTAAEDDNEGD 312
Query: 324 KKDAKKDAKKN-AKKDEKKDAKKKG 347
KK KKD KK +K+EK+ KKKG
Sbjct: 313 KK--KKDKKKKKGEKEEKEKEKKKG 335
Score = 74.7 bits (182), Expect = 1e-13
Identities = 59/241 (24%), Positives = 118/241 (48%), Gaps = 16/241 (6%)
Query: 112 AEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKG 171
+ I GE + S K+ +K+ K G +IE G E+ + K +K AEK
Sbjct: 178 SRINSSGESGDESDEFLQSRKGQKKNQKN-KPGPNIESGNEDDDASFKIKTVAQKKAEKK 236
Query: 172 KDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSA 231
+ + ++EK +K +K++ ++ K KD + + E + +K ++++ K K
Sbjct: 237 ERERKKRDEEKAKLRKLKEKEELETGK-KDQSKQKESQ--------RKFEEETVKSK-VT 286
Query: 232 IELQAVKADEKKDE--DGKKDANKGDESKDAKKDAKEIK--KGKKDKKKPSSTDSDSKDD 287
++ + A E+K E +D N+GD+ K KK K K K K+ KK PS + +
Sbjct: 287 VDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQE 346
Query: 288 VKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKG 347
+ K++ + ++ ++ E ++K+ ++ +++ K++ KK +K+ K+ KK+G
Sbjct: 347 ALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQE-KRERKKQKEKERKERLKKEG 405
Query: 348 K 348
K
Sbjct: 406 K 406
Score = 73.9 bits (180), Expect = 2e-13
Identities = 64/268 (23%), Positives = 121/268 (45%), Gaps = 36/268 (13%)
Query: 117 KGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKE-EKLDAKKDSKKGKKDAEKGK--- 172
KG+ + + K SE + KK ++ + G+ ++ D S+KG+K +K K
Sbjct: 151 KGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGP 210
Query: 173 --DSATESED---------EKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGK 221
+S E +D +K KK+ ++ K+D K K + + E +KD K K
Sbjct: 211 NIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQK 270
Query: 222 KDSKKGKDSAIELQA------VKADEKKDED--GKKDANKGDESKDAKKDAKEIK--KGK 271
+ +K ++ ++ + + A E+K E +D N+GD+ K KK K K K K
Sbjct: 271 ESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEK 330
Query: 272 KDKKKPSSTDSDSKDD----VKKESKKDATKDAKKV-------AKKDTEKESADSKKDAK 320
+ KK PS + + +K+E ++ ++ +++ AK+ E+ K++ K
Sbjct: 331 EKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERK 390
Query: 321 KNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
K +K+ K+ KK K K + + +
Sbjct: 391 KQKEKERKERLKKEGKLLTKSQREARAR 418
Score = 67.8 bits (164), Expect = 1e-11
Identities = 67/273 (24%), Positives = 122/273 (44%), Gaps = 36/273 (13%)
Query: 105 VEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKG 164
+++D+ AAEI G K + + + + ++ K+D + +++ +E L+A+
Sbjct: 17 IDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGI---- 72
Query: 165 KKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKG-KDSATESEGEKGGTEKDSKKGKKD 223
K D E TE+ +E+ +K KK +K + D+ +E +K K + K K +
Sbjct: 73 KADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVE 132
Query: 224 SKKGKDSAIEL---------QAVKADEK-----KDEDGKK----------DANKGDESKD 259
G D + +A K+++K +DED K GDES +
Sbjct: 133 MYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDE 192
Query: 260 AKKDAKEIKKGKKDKKKPSSTDSDSKDD----VKKESKKDATKDAKKVAKKDTEKESAD- 314
+ K KK +K+K P+ + DD +K ++K A K ++ K+D EK
Sbjct: 193 FLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRK 252
Query: 315 -SKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
+K+ + KKD K K++ +K E++ K K
Sbjct: 253 LKEKEELETGKKDQSKQ-KESQRKFEEETVKSK 284
Score = 65.9 bits (159), Expect = 5e-11
Identities = 59/234 (25%), Positives = 107/234 (45%), Gaps = 15/234 (6%)
Query: 119 EDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATES 178
+D + K T ++ + ++ +++ KK +D EK K KL K++ + GKKD K K+S +
Sbjct: 218 DDDASFKIKTVAQKKAEKKERERKK-RDEEKAKLRKLKEKEELETGKKDQSKQKESQRKF 276
Query: 179 EDEKGGAKKDNKKDKKDSNKGKDSATESEGE-----KGGTEKDSKKGKKDSKKGKDSAIE 233
E+E K K + G A+E + E + E D KK K KKG+ E
Sbjct: 277 EEE-------TVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKE 329
Query: 234 LQAVKADEKKDEDGKKDA-NKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKES 292
+ K K ++A K E ++ +K +E + + ++ + + + + K+E
Sbjct: 330 KEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRER 389
Query: 293 KKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
KK K+ K+ KK+ K S+++A+ A+ K + + K KK
Sbjct: 390 KKQKEKERKERLKKE-GKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKK 442
Score = 64.3 bits (155), Expect = 2e-10
Identities = 61/244 (25%), Positives = 121/244 (49%), Gaps = 26/244 (10%)
Query: 116 KKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGK--- 172
KK E K ++ D E K + K+ +++E GK+++ K+ +K +++ K K
Sbjct: 231 KKAEKKERERKKRDEE---KAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTV 287
Query: 173 -----DSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKG-KKDSKK 226
++ E + A+ DN+ DKK +K K +GEK EK+ KKG K + K
Sbjct: 288 DTGVIPASEEKAETPTAAEDDNEGDKKKKDKKK-----KKGEKEEKEKEKKKGPSKATVK 342
Query: 227 GKDSAIELQAVKADEKKDEDGKKDANKGDESKDAK-KDAKEIKKGKKDKKKPSSTDSDSK 285
A L +K +E++ + +++ K E +AK K+ + +++ K+++KK + + K
Sbjct: 343 AMQEA--LAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKK--QKEKERK 398
Query: 286 DDVKKESK--KDATKDAKKVAKKDTEKESADSKKDAKKNA--KKDAKKDAKKNAKKDEKK 341
+ +KKE K + ++A+ A+ + A + K++ KK + KK K ++
Sbjct: 399 ERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQL 458
Query: 342 DAKK 345
++K+
Sbjct: 459 ESKE 462
Score = 60.5 bits (145), Expect = 2e-09
Identities = 60/218 (27%), Positives = 102/218 (46%), Gaps = 33/218 (15%)
Query: 150 GKEEKLDAKKDSKKGKKDAE------KGKDSATESEDEKGGAKKDNKKDKKDSNKG---- 199
GK++K + +DS K D + +G +A E E +K KK +K K+D ++
Sbjct: 2 GKKQK-NKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILK 60
Query: 200 --KDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKK---DANKG 254
++ + E++G K E + K +++++ S K +KK + GKK D N
Sbjct: 61 ELEELSLEAQGIKADRETVAVKPTENNEEEFTS-------KDKKKKGQKGKKQSFDDNDS 113
Query: 255 DESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESAD 314
+E +D KD+K K K + S +D D DD K KK K K K D +E D
Sbjct: 114 EELED--KDSKSKKTAKPKVEMYSGSDDD--DDFNKLPKKAKGKAQKSNKKWDGSEEDED 169
Query: 315 SKKDAKKNAKKDA------KKDAKKNAKKDEKKDAKKK 346
+ K K+ ++ ++ + D ++K +KK+ K K
Sbjct: 170 NSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNK 207
Score = 57.8 bits (138), Expect = 1e-08
Identities = 52/192 (27%), Positives = 84/192 (43%), Gaps = 21/192 (10%)
Query: 164 GKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKD 223
GKK K +DS + D A + +G +A E E +K +K +K K+D
Sbjct: 2 GKKQKNKSEDSTKDDIDLDALAAEI---------EGAGAAKEQEPQKSKGKKKKEKKKQD 52
Query: 224 S------KKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKP 277
K+ ++ ++E Q +KAD E + +E + KD K KKG+K KK+
Sbjct: 53 FDEDDILKELEELSLEAQGIKADR---ETVAVKPTENNEEEFTSKDKK--KKGQKGKKQS 107
Query: 278 -SSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAK 336
DS+ +D +SKK A + + D + + K AK A+K KK
Sbjct: 108 FDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEED 167
Query: 337 KDEKKDAKKKGK 348
+D K K++ +
Sbjct: 168 EDNSKKIKERSR 179
Score = 45.8 bits (107), Expect = 6e-05
Identities = 57/281 (20%), Positives = 125/281 (44%), Gaps = 53/281 (18%)
Query: 116 KKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSA 175
KKG K T K ++ ++LK+ ++ K+ ++ + E+L+AK+ ++ + + EK +
Sbjct: 333 KKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEE-RLEQEKRERKK 391
Query: 176 TESEDEKGGAKKDNKKDKKDSN--KGKDSATESEGEKGGTE---KDS----------KKG 220
+ ++ K KK+ K K + + AT + G E KDS KK
Sbjct: 392 QKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKR 451
Query: 221 KK-----DSKKGKDS-----AIELQAVKADEKKDEDGKKDANKGDESKDAKKD------- 263
KK +SK+ +S A+E+ EK++ + + ++++DA D
Sbjct: 452 KKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMAS 511
Query: 264 ---------------AKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATK---DAKKVAK 305
KE + ++++++ D +S+++ ++E + + ++ + +KV+
Sbjct: 512 DEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSD 571
Query: 306 KDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
+ ++ D K K D++ D+ + K+E+ K K
Sbjct: 572 EKDSGKTLDKK--PSKEMSSDSEYDSDDDRTKEERAYDKAK 610
Score = 44.3 bits (103), Expect = 2e-04
Identities = 47/250 (18%), Positives = 112/250 (44%), Gaps = 35/250 (14%)
Query: 131 ESELKQGKKDSKKGKDIEKGKEEKLDAK---KDSKKGKKDAEK-------------GKDS 174
E L+Q K++ KK K+ E+ + K + K K ++ + AE KDS
Sbjct: 379 EERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDS 438
Query: 175 ATES----EDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDS 230
+ ED+K + K+ S + A E+G EK+ + ++ +D+
Sbjct: 439 LPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDT 498
Query: 231 AI----ELQAVKADEKKDE--------DGKKDANKGDESKDAKKDAKEIKKGKKDKKKPS 278
+ +A+ +DE+ ++ + K++ + +E ++ +++ +E ++ ++++ +
Sbjct: 499 EDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESE 558
Query: 279 STDSDSKDDV---KKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNA 335
++ D +D+ +K+S K K K D+E +S D + ++ K ++ K+
Sbjct: 559 GSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRL 618
Query: 336 KKDEKKDAKK 345
+ + + +K
Sbjct: 619 EHSKNVNTEK 628
Score = 42.4 bits (98), Expect = 6e-04
Identities = 29/105 (27%), Positives = 59/105 (56%), Gaps = 6/105 (5%)
Query: 128 TDSESELKQGKK---DSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGG 184
+D E+E +G K + K+ + E+ +EE+ + ++S++ +++ + + S + EDEK
Sbjct: 511 SDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVS 570
Query: 185 AKKDNKK--DKKDSNK-GKDSATESEGEKGGTEKDSKKGKKDSKK 226
+KD+ K DKK S + DS +S+ ++ E+ K K+ +K
Sbjct: 571 DEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEK 615
Score = 36.2 bits (82), Expect = 0.045
Identities = 30/148 (20%), Positives = 71/148 (47%), Gaps = 14/148 (9%)
Query: 124 QKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKG 183
++DT D+ + + ++ + +E G + ++ K++ ++ +++ E+ E EDE
Sbjct: 495 EEDTEDAGLDDWEAMASDEETEKVE-GNKVHIEVKENPEEEEEEEEE------EEEDE-- 545
Query: 184 GAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKK 243
++++++++ + + S + E EK EKDS K D K K+ + + + D++
Sbjct: 546 ----ESEEEEEEEGESEGSEGDEEDEKVSDEKDSGK-TLDKKPSKEMSSDSEYDSDDDRT 600
Query: 244 DEDGKKDANKGDESKDAKKDAKEIKKGK 271
E+ D K K + +K + K
Sbjct: 601 KEERAYDKAKRRIEKRRLEHSKNVNTEK 628
Score = 33.1 bits (74), Expect = 0.38
Identities = 22/96 (22%), Positives = 51/96 (53%), Gaps = 8/96 (8%)
Query: 105 VEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKG 164
V ++ K ++ E++ ++D E E ++G+ + +G + ++EK+ +KDS K
Sbjct: 523 VHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDE----EDEKVSDEKDSGK- 577
Query: 165 KKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGK 200
D + K+ +++SE + + D K+++ +K K
Sbjct: 578 TLDKKPSKEMSSDSEYD---SDDDRTKEERAYDKAK 610
Score = 31.2 bits (69), Expect = 1.4
Identities = 22/91 (24%), Positives = 40/91 (43%), Gaps = 1/91 (1%)
Query: 86 ERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTT-DSESELKQGKKDSKKG 144
E V++ + P + E + + E ++ E++ + + D E E +KDS K
Sbjct: 519 EGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKT 578
Query: 145 KDIEKGKEEKLDAKKDSKKGKKDAEKGKDSA 175
D + KE D++ DS + E+ D A
Sbjct: 579 LDKKPSKEMSSDSEYDSDDDRTKEERAYDKA 609
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 84.0 bits (206), Expect = 2e-16
Identities = 87/299 (29%), Positives = 137/299 (45%), Gaps = 52/299 (17%)
Query: 68 RGDRRQPLWMYRSLMRISERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDT 127
+GD RQ R S R S L +KP RT S + ++ K + DT
Sbjct: 9 QGDMRQ------EPKRRSARLSAMLVPVTPEVKPKRT----SSSRKMKTKSDMMEENIDT 58
Query: 128 T-DSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAK 186
+ + +E KQ + + K E K+ ++ +K+ + K+ E EKGG K
Sbjct: 59 SAQAVAETKQEAVVEEDYNENAKNGEAKIT---EAPASEKEIVEVKEENIEDATEKGGEK 115
Query: 187 K------------DNKKDKKDSNKGKDSA-TESEGEKGGTEKDSKKGKKDSKKGKDSAIE 233
K D K+D++D N+ K A E + EKG E+D K+ K ++KG+D+
Sbjct: 116 KEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKG--EEDGKEDKNGNEKGEDAK-- 171
Query: 234 LQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESK 293
K D KK EDGK G++ K+ +D KE ++D+K+ D +D K++
Sbjct: 172 ---EKEDGKKGEDGK---GNGEDGKEKGEDEKE----EEDRKETG--DGKENEDGKEKGD 219
Query: 294 KDATKDAKKVAKKDTEKESADSKKDAKKN------AKKDAKKDAKKNAKKDEKKDAKKK 346
K K+ K V K+ EKE D K+D N K+D K++ + + + K+D KK
Sbjct: 220 K---KEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKK 275
Score = 83.6 bits (205), Expect = 2e-16
Identities = 66/221 (29%), Positives = 113/221 (51%), Gaps = 24/221 (10%)
Query: 107 VDSKAAEIGKKGEDKTTQKDTTDSES-ELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGK 165
V+ E K GE K T+ ++ E E+K+ + K EK + + K + + K
Sbjct: 72 VEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQK 131
Query: 166 KDAE-----KGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKG----GTEKD 216
+D E KG ++ E +DEKG ++D K+DK + KG+D+ + +G+KG G +D
Sbjct: 132 EDEEDQNEEKG-EAGKEDKDEKG--EEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGED 188
Query: 217 SKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKD--AKKDAKEIKKGKKDK 274
K+ +D K+ +D + D K++EDGK+ +K E KD K+D KE + GK+D+
Sbjct: 189 GKEKGEDEKEEED-----RKETGDGKENEDGKEKGDK-KEGKDVKVKEDEKEREDGKEDE 242
Query: 275 KKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADS 315
K+D+K+E + K+ ++ + D +KE S
Sbjct: 243 GGNEEEAGKEKEDLKEE---EEGKEEDEIKEDDGKKEEPQS 280
Score = 83.6 bits (205), Expect = 2e-16
Identities = 66/202 (32%), Positives = 107/202 (52%), Gaps = 24/202 (11%)
Query: 98 PLKPTRTVEVDSKAAEIG--KKGEDK-TTQKDTTDSESELKQGKKDS--KKGKDIEKGKE 152
P VEV + E K GE K + + E + K+ ++D +KG+ ++ K+
Sbjct: 91 PASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKD 150
Query: 153 EKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGG 212
EK ++D K+ K EKG+D+ + + +KG K N +D K+ KG+D E + ++ G
Sbjct: 151 EK--GEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKE--KGEDEKEEEDRKETG 206
Query: 213 TEKDSKKGKK--DSKKGKDSAIELQAVKADEKKDEDGKKD-ANKGDESKDAKKDAKEIKK 269
K+++ GK+ D K+GKD VK DEK+ EDGK+D +E+ K+D KE ++
Sbjct: 207 DGKENEDGKEKGDKKEGKD-----VKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEE 261
Query: 270 GKKDKKKPSSTDSDSKDDVKKE 291
GK++ D +DD KKE
Sbjct: 262 GKEE-------DEIKEDDGKKE 276
Score = 72.0 bits (175), Expect = 7e-13
Identities = 68/263 (25%), Positives = 118/263 (44%), Gaps = 28/263 (10%)
Query: 86 ERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGK 145
+R S L+A P+ P EV K +K + K+ + S +
Sbjct: 17 KRRSARLSAMLVPVTP----EVKPKRTSSSRKMKTKSDMMEENIDTS-----------AQ 61
Query: 146 DIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATE 205
+ + K+E + ++D + K+ E A SE E K++N +D + K A
Sbjct: 62 AVAETKQEAV-VEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVA 120
Query: 206 SEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAK 265
+E + E+D K+ ++D + K E DEK +EDGK+D N ++ +DAK+ K
Sbjct: 121 AEVK--NEEEDQKEDEEDQNEEKG---EAGKEDKDEKGEEDGKEDKNGNEKGEDAKE--K 173
Query: 266 EIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKK 325
E K +D K + +D K+E + T D K + + KE D K+ K+
Sbjct: 174 EDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGK---ENEDGKEKGDKKEGKDVKVKE 230
Query: 326 DAKKDAKKNAKKDEKKDAKKKGK 348
D K+ +++ K+DE + ++ GK
Sbjct: 231 DEKE--REDGKEDEGGNEEEAGK 251
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 84.0 bits (206), Expect = 2e-16
Identities = 70/212 (33%), Positives = 107/212 (50%), Gaps = 18/212 (8%)
Query: 151 KEEKLDAKKDSKKGKKDAEK---GKDSATESEDEKGGAKKDN---KKDKKDSNK----GK 200
K+ KL + DS++ K A K K ES++E K N K K +S + K
Sbjct: 531 KQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKK 590
Query: 201 DSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQA--VKADEKKDEDGKKDANKGDESK 258
D ++E + TEK+ K++ K E QA VK K++ KK+ E K
Sbjct: 591 DKPIKTETKPSVTEKE-VPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDK 649
Query: 259 DAKKDAKEIKKGKKDKKKP-SSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKES--ADS 315
+K+ + + KK+ K P + K++VKKE KK+ K+ KK KK+ +KE+ +
Sbjct: 650 KEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEV 709
Query: 316 KKDAKKNAKKDAKKDAKKNAKKDEK--KDAKK 345
KK+ KK KK+ KK+ K+ K+ +K KDAKK
Sbjct: 710 KKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKK 741
Score = 71.2 bits (173), Expect = 1e-12
Identities = 76/256 (29%), Positives = 122/256 (47%), Gaps = 28/256 (10%)
Query: 93 AARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKE 152
A R+ LKP + SK+ + E K + T K K +SK+ ++K K
Sbjct: 539 ADSRESLKPAAK-PLPSKSV----RKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKP 593
Query: 153 EKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGG 212
K + K S K+ K + S ++E + A K K+ K++ + E +K
Sbjct: 594 IKTETKP-SVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKK-- 650
Query: 213 TEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKK 272
++ +K KK+ K +D K KK+E KK+ K K+ KK+ K K+ KK
Sbjct: 651 --EEKEKPKKEVAKKED--------KTPIKKEEKPKKEEVK----KEVKKEIK--KEEKK 694
Query: 273 DKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAK--KDAKKD 330
+ KK ++ K +VKKE KK+ K+ KK +K+ +KE KDAKK++ +AKK
Sbjct: 695 EPKKEVKKETPPK-EVKKEVKKEEKKEVKK-EEKEPKKEIKKLPKDAKKSSTPLSEAKKP 752
Query: 331 AKKNAKKDEKKDAKKK 346
A K +K+++ KK
Sbjct: 753 AALKPKVPKKEESVKK 768
Score = 69.3 bits (168), Expect = 5e-12
Identities = 72/248 (29%), Positives = 114/248 (45%), Gaps = 41/248 (16%)
Query: 106 EVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGK 165
+V+SK + KK DK + +T S +E + K+ E +++ D K K
Sbjct: 579 KVESKEKVMVKK--DKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKP---KAA 633
Query: 166 KDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSK 225
K+ K++ + ED+K ++ +K KK+ K +D + EK E+ K+ KK+ K
Sbjct: 634 KEKTVKKETKVKPEDKK----EEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIK 689
Query: 226 KGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAK--EIKKGKKDKKKPSSTDSD 283
K +EKK+ KK+ K K+ KK+ K E K+ KK++K+P
Sbjct: 690 K-------------EEKKEP--KKEVKKETPPKEVKKEVKKEEKKEVKKEEKEP------ 728
Query: 284 SKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEK--- 340
KKE KK KDAKK + +E + + K ++ KKD+ K EK
Sbjct: 729 -----KKEIKK-LPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKI 782
Query: 341 KDAKKKGK 348
K KK+GK
Sbjct: 783 KVIKKEGK 790
Score = 59.7 bits (143), Expect = 4e-09
Identities = 61/246 (24%), Positives = 104/246 (42%), Gaps = 33/246 (13%)
Query: 86 ERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGK 145
E+P + + +K + ++ ++K + K+ K +E + K K
Sbjct: 575 EKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAK 634
Query: 146 DIEKGKEEKL---DAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDS 202
+ KE K+ D K++ +K KK+ AKK++K K K K
Sbjct: 635 EKTVKKETKVKPEDKKEEKEKPKKEV----------------AKKEDKTPIKKEEKPKKE 678
Query: 203 ATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKK 262
+ E +K +++ K+ KK+ KK + VK + KK+E K + K+ K+
Sbjct: 679 EVKKEVKKEIKKEEKKEPKKEVKKETPP----KEVKKEVKKEE-------KKEVKKEEKE 727
Query: 263 DAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKN 322
KEIKK KD KK S+ S++K K + K ++ KKD+ +K K
Sbjct: 728 PKKEIKKLPKDAKKSSTPLSEAK---KPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKV 784
Query: 323 AKKDAK 328
KK+ K
Sbjct: 785 IKKEGK 790
Score = 57.0 bits (136), Expect = 2e-08
Identities = 53/196 (27%), Positives = 93/196 (47%), Gaps = 14/196 (7%)
Query: 82 MRISERPSVY---LAARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGK 138
++ +PSV + ++ +P P + + +A ++ K + T K T + E K+ +
Sbjct: 594 IKTETKPSVTEKEVPSKEEP-SPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEE 652
Query: 139 KDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNK 198
K+ K K++ K KE+K KK+ K K++ +K + E+ KK+ KK+ K
Sbjct: 653 KEKPK-KEVAK-KEDKTPIKKEEKPKKEEVKKEVKKEIKKEE-----KKEPKKEVKKETP 705
Query: 199 GKDSATE-SEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDES 257
K+ E + EK +K+ K+ KK+ KK A + ++ KK K K +ES
Sbjct: 706 PKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEES 765
Query: 258 --KDAKKDAKEIKKGK 271
KD+ K +KGK
Sbjct: 766 VKKDSVAAGKPKEKGK 781
Score = 53.1 bits (126), Expect = 4e-07
Identities = 55/261 (21%), Positives = 118/261 (45%), Gaps = 9/261 (3%)
Query: 87 RPSVYLAARRQPLKPTRTVE--VDSKAAEIGK-KGEDKTTQKDTTDSESELKQGKKDSKK 143
+P + L + LK T VE V K E+ K E TT+ E E +Q ++ +
Sbjct: 855 KPQLELIEDEEKLKETEPVEAYVIQKEREVTKGPAESPDEGITTTEGEGECEQTPEELEP 914
Query: 144 GKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSA 203
+EK + ++ +D G +++ + D ++E E+ +++ ++ + K S
Sbjct: 915 ---VEKQGVDDIEKFEDEGAGFEESSETGDYEEKAETEEAEEPEEDGEEHVCVSASKHSP 971
Query: 204 TESEGEKGGTEKDSK-KGKKDSKKGKDSAIELQAVKADEKKD-EDGKKDANKGDESKDAK 261
TE E E E D+ + K++S D E +A EK + E +++A++ D+++DA+
Sbjct: 972 TEDE-ESAKAEADAYIREKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAEDAR 1030
Query: 262 KDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKK 321
++ E +K + + + D ++ +E T K++ + +E A S D
Sbjct: 1031 EEEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPTKQLGAQSPGREPASSIHDETL 1090
Query: 322 NAKKDAKKDAKKNAKKDEKKD 342
+++ A ++++ +
Sbjct: 1091 PGGSESEATASDEENREDQPE 1111
Score = 35.4 bits (80), Expect = 0.076
Identities = 30/103 (29%), Positives = 39/103 (37%), Gaps = 3/103 (2%)
Query: 235 QAVKADEKKDEDGKKDANKGDESKDAKK-DAKEIKKGKKDKKKPSSTDSDSKDDVKKESK 293
+A+K D K+ KK K S KK D K K SD V K
Sbjct: 2233 KALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPKK 2292
Query: 294 KDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAK 336
K++ + A K K + +KD K K A A K+AK
Sbjct: 2293 KESVEKAAKPTTTPEVKAARGEEKD--KETKNAANASASKSAK 2333
Score = 35.4 bits (80), Expect = 0.076
Identities = 29/91 (31%), Positives = 41/91 (45%), Gaps = 4/91 (4%)
Query: 258 KDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDA--KKVAKKDTEKESADS 315
K KKD KE K KK K S+ K D K + + K A K+ + K + S
Sbjct: 2233 KALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPKK 2292
Query: 316 KKDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
K+ +K AK + K A + E+KD + K
Sbjct: 2293 KESVEKAAKPTTTPEVK--AARGEEKDKETK 2321
Score = 30.4 bits (67), Expect = 2.5
Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 144 GKDIEKGKEEKLDAKKDSKKGKKDA----EKGKDSATESEDEKGGAKKDNKK-DKKDSNK 198
GK ++K +EK KK K K + GK + + G K+ + K + S K
Sbjct: 2232 GKALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPK 2291
Query: 199 GKDSATESEGEKGGTEKDSKKGKKDSKKGKDSA 231
K+S ++ E + +G++ K+ K++A
Sbjct: 2292 KKESVEKAAKPTTTPEVKAARGEEKDKETKNAA 2324
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 82.8 bits (203), Expect = 4e-16
Identities = 79/269 (29%), Positives = 117/269 (43%), Gaps = 43/269 (15%)
Query: 119 EDKTTQKDTTDSE-SELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATE 177
ED +DT E E KK+ K K K+EK + K +K K+ EKGK+ E
Sbjct: 120 EDDDGDEDTDKGEIDEPPLRKKEIHKDKT---EKQEKPERKIQTKVTHKEKEKGKEKVRE 176
Query: 178 SEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAV 237
E + A K +KK+ + K A E + K EK +K KK+ K GK ++ A
Sbjct: 177 KEKPEKKATHKEKIEKKEKPETKTLAKEQKKAK-TAEKSEEKTKKEVKGGKQEKVKQTAA 235
Query: 238 KADE--------KKDEDGKKDANKGDESKDAKKDAK---------EIKKGKK-------- 272
K E K+ ED +K A E KD + ++K G+
Sbjct: 236 KVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLP 295
Query: 273 ----DKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKES-------ADSKKDAKK 321
+ P+S + K+ KK+++K T + KK K+D +K+S + K+ K
Sbjct: 296 TEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKA 355
Query: 322 NAKKD--AKKDAKKNAKKDEKKDAKKKGK 348
+ K K A+ AKKDEKK+ KK K
Sbjct: 356 SETKQGTVKIAAQAAAKKDEKKEDSKKTK 384
Score = 71.6 bits (174), Expect = 1e-12
Identities = 77/275 (28%), Positives = 117/275 (42%), Gaps = 49/275 (17%)
Query: 111 AAEIGKKGED-----KTTQKDTTD---------SESELKQGKKDSKKGKDIEKGKEEKLD 156
A+ I K G D + ++TTD S+ + ++D +D +KG+ ++
Sbjct: 78 ASSIAKIGSDPLKLVRDAMEETTDWIYGFFSLLSDIISSEDEEDDDGDEDTDKGEIDEPP 137
Query: 157 AKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESE-GEKGGTEK 215
+K K+ K K TE + EK K K K+ KGK+ E E EK T K
Sbjct: 138 LRK------KEIHKDK---TEKQ-EKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHK 187
Query: 216 DSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKK 275
+ K KK+ + K A E + K EK +E KK+ KG + + K+ A ++K+ +K
Sbjct: 188 E-KIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEV-KGGKQEKVKQTAAKVKEVQKTPS 245
Query: 276 KPSSTDSDSKDDVKKESKKDA---------------TKDAKKVA---KKDTEKES----A 313
KP + K V K +KD K + A TE+ S A
Sbjct: 246 KPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPA 305
Query: 314 DSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
+ K+ KK A+K KK EK+D KKK +
Sbjct: 306 SPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSE 340
Score = 63.9 bits (154), Expect = 2e-10
Identities = 64/232 (27%), Positives = 108/232 (46%), Gaps = 15/232 (6%)
Query: 116 KKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDA-KKDSKKGKKDAEKGKDS 174
K+GE K +K T SE++ K+ K+D KK + KE +D KK+ K + +
Sbjct: 312 KEGEKKKAEKKVT-SETKKKE-KEDIKKKSE----KETAIDVEKKEPGKASETKQGTVKI 365
Query: 175 ATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIEL 234
A ++ +K K+D+KK KK + + + E ++ E +K KK+ D ++
Sbjct: 366 AAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVE-PAKSPKKEHSVPSDKQVK- 423
Query: 235 QAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKG-KKDKKKPSSTDSDSKDDVK-KES 292
K + K+E G K K +K K +++ +K+K +S+ K+ +K KE
Sbjct: 424 --AKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEE 481
Query: 293 KKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAK 344
K A+ K+ K EK S K+ K + KK+ K + KK+AK
Sbjct: 482 KVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEK--PEPQIKKEAK 531
Score = 62.8 bits (151), Expect = 4e-10
Identities = 79/295 (26%), Positives = 115/295 (38%), Gaps = 41/295 (13%)
Query: 85 SERPSVYLAARRQPLKPTRTVEVDSK-AAEIGKKGEDKTTQKDTTDSESELKQ--GKKDS 141
SE+ + +++P K + T + K AA+ K ++K T +E++Q GKK
Sbjct: 339 SEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQE 398
Query: 142 KKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKK--DKKDSNKG 199
KK K +E K K + S K K + TE E+ GA K KK+
Sbjct: 399 KKEKHVEPAKSPKKEHSVPSDKQVK-------AKTERAKEEIGAVSIKKAVPGKKEEKTT 451
Query: 200 KDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQA------VKADEKKDEDGKKDANK 253
K E EK G K K+ K GK+ + K DEK + GK+ K
Sbjct: 452 KTVEQEIRKEKSGKTSSILKDKEPIK-GKEEKVPASLKEKEPETKKDEKMSKAGKEVKPK 510
Query: 254 GD--ESKDAKKDAKEIKK------------GKKDKKKPSSTDSDSKDDVKKESKKDATKD 299
+ K +K +IKK K+D KP T S K + K + A
Sbjct: 511 PPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTI 570
Query: 300 AKKVAKKDT------EKESADSKKDAKKNAKKDAKKDAKKNAKKDE--KKDAKKK 346
K K T E+E K D K K + + KK E +K++K+K
Sbjct: 571 EKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKESKEK 625
Score = 61.2 bits (147), Expect = 1e-09
Identities = 90/354 (25%), Positives = 131/354 (37%), Gaps = 109/354 (30%)
Query: 100 KPTRTVE--VDSKAAEIGK-------KGEDKTTQKDTTDSES--ELKQGKKDSKKGKDIE 148
KP R ++ V K E GK K E K T K+ + + E K K+ KK K E
Sbjct: 153 KPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAE 212
Query: 149 KGKEEKLDAKKDSKKGK-----------KDAEKGKDSATESED-EKGGAKKDNKKDKK-- 194
K +E+ KK+ K GK K+ +K E ED EK K +KD+
Sbjct: 213 KSEEK---TKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAF 269
Query: 195 -----------DSNKGKDSAT--------------------ESEGEKGGTEKD-----SK 218
D G+ A E EGEK EK K
Sbjct: 270 CRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKK 329
Query: 219 KGKKDSKKG--KDSAIELQ---------------------AVKADEKKDEDGKK------ 249
K K+D KK K++AI+++ A K DEKK ED KK
Sbjct: 330 KEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKK-EDSKKTKKPAE 388
Query: 250 -DANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKE--------------SKK 294
+ KG + + +K + K KK+ PS +K + KE ++
Sbjct: 389 VEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEE 448
Query: 295 DATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
TK ++ +K+ +++ KD + K+ K A K+ E K +K K
Sbjct: 449 KTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSK 502
Score = 59.7 bits (143), Expect = 4e-09
Identities = 70/246 (28%), Positives = 111/246 (45%), Gaps = 34/246 (13%)
Query: 107 VDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDS-KKGKDIEKGKEEKLDA-----KKD 160
V K A GKK E+KTT+ + E K GK S K K+ KGKEEK+ A + +
Sbjct: 436 VSIKKAVPGKK-EEKTTKTVEQEIRKE-KSGKTSSILKDKEPIKGKEEKVPASLKEKEPE 493
Query: 161 SKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATES---------EGEKG 211
+KK +K ++ GK+ + +G KK+ K + + + K + +E + EK
Sbjct: 494 TKKDEKMSKAGKEVKPKPPQLQG--KKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEK- 550
Query: 212 GTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKD--ANKGDESKDAKKDAKEIKK 269
T K +K K+ K IE A KK E +++ + K D+ K K E+ +
Sbjct: 551 -TVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTE 609
Query: 270 GKKDKKKPSSTDSDSKDDVK--KESKKDATKD---------AKKVAKKDTEKESADSKKD 318
K K + S +S K D+K +E K K+ A+K A+ + E + K
Sbjct: 610 SGKKKTEISEKESKEKADMKHLREEKVSTRKESLQLHNVTKAEKPARVSKDVEDVPASKK 669
Query: 319 AKKNAK 324
AK+ +
Sbjct: 670 AKEGTE 675
Score = 52.4 bits (124), Expect = 6e-07
Identities = 60/220 (27%), Positives = 101/220 (45%), Gaps = 35/220 (15%)
Query: 160 DSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKG-------- 211
+ K+G+K + K ++ + EK KK ++K+ + K+ SE ++G
Sbjct: 310 EEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQA 369
Query: 212 GTEKDSKKGKKDSKKGKDSA-IELQAVKADEKKDE-------DGKKDANKGDESKDAKKD 263
+KD K K+DSKK K A +E K EKK++ K+ + D+ AK +
Sbjct: 370 AAKKDEK--KEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTE 427
Query: 264 -AKE------IKKGKKDKKKPSSTDSDSKDDVKKESKKDAT--KDAKKVAKKD------- 307
AKE IKK KK+ +T + ++ K++S K ++ KD + + K+
Sbjct: 428 RAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASL 487
Query: 308 TEKESADSKKDAKKNAKKDAK-KDAKKNAKKDEKKDAKKK 346
EKE K + A K+ K K + KK+EK + + K
Sbjct: 488 KEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIK 527
Score = 35.0 bits (79), Expect = 0.100
Identities = 28/108 (25%), Positives = 52/108 (48%), Gaps = 4/108 (3%)
Query: 100 KPTRTVEVDSKAAEIGKKGEDKTTQKDTTD-SESELKQ---GKKDSKKGKDIEKGKEEKL 155
KPT+ E + K + K T K T++ +ES K+ +K+SK+ D++ +EEK+
Sbjct: 577 KPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKESKEKADMKHLREEKV 636
Query: 156 DAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSA 203
+K+S + + K + + E A K K+ +D + K +
Sbjct: 637 STRKESLQLHNVTKAEKPARVSKDVEDVPASKKAKEGTEDVSPTKQKS 684
Score = 34.3 bits (77), Expect = 0.17
Identities = 45/207 (21%), Positives = 81/207 (39%), Gaps = 24/207 (11%)
Query: 43 PGTKRRSKPSQIRDNTVSIIDEE------QLRG---DRRQPLWMYRSLMRISERPSVYLA 93
P + + +P +D +S +E QL+G ++ +P + ISE+ ++
Sbjct: 484 PASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIH-- 541
Query: 94 ARRQPLKPTRTVEVDS---------KAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKG 144
++ +KP +TV KA I K + K T+K E E K D K
Sbjct: 542 -KQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKK-AEHREREPPSIKTD--KP 597
Query: 145 KDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSAT 204
K KG E ++ K + + K K +EK +K++ + + K +
Sbjct: 598 KPTPKGTSEVTESGKKKTEISEKESKEKADMKHLREEKVSTRKESLQLHNVTKAEKPARV 657
Query: 205 ESEGEKGGTEKDSKKGKKDSKKGKDSA 231
+ E K +K+G +D K +
Sbjct: 658 SKDVEDVPASKKAKEGTEDVSPTKQKS 684
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 81.6 bits (200), Expect = 9e-16
Identities = 66/332 (19%), Positives = 147/332 (44%), Gaps = 38/332 (11%)
Query: 21 SELSKKSWNQQHFALLFPKPQRPGTKR-----RSKPSQIRDNTVSIIDEEQLRGDRRQPL 75
S L+K W F+ LFP+ P K +++P +I+ + +E +RR+
Sbjct: 206 SFLTKLEW----FSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRR-- 259
Query: 76 WMYRSLMRISERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELK 135
S P L+ RR P + +R+ + + +K+ E E K
Sbjct: 260 ---------SRSPRRSLSPRRSPRR-SRSRSHHREGHGSSSFDRELEREKERQRLEREAK 309
Query: 136 QGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKD 195
+ +K+ ++ + I++G E + ++ + S + S D KG + +++ +K+
Sbjct: 310 EREKERRRSRSIDRGLERRRSRSRERHR----------SRSRSRDRKGDRRDRDREREKE 359
Query: 196 SNKGKDSATESEGEKGG-TEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKG 254
+ +G+ + + E+G EK+ ++ ++ SK+ + + +EKK ++ K D
Sbjct: 360 NERGRRRDRDYDKERGNEREKERERSRERSKEQRSRG------EVEEKKHKEDKDDRRHR 413
Query: 255 DESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESAD 314
D+ +D+KK+ K + +++K S + S + + K+ + K +K+ + K S
Sbjct: 414 DDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRS 473
Query: 315 SKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
+ + +K K++ + +K K+ K+
Sbjct: 474 GSQGRTDSVEKSKKREHSPSKEKSRKRSRSKE 505
Score = 59.7 bits (143), Expect = 4e-09
Identities = 56/288 (19%), Positives = 118/288 (40%), Gaps = 16/288 (5%)
Query: 40 PQRPGTKRRSKPSQIRDNTVSIIDEEQLRGDRRQPLWMYRSLMRISERPSVYLAARRQPL 99
P+R + RS+ + S D E R RQ L R S + +
Sbjct: 269 PRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERR 328
Query: 100 KPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKK 159
+ S++ +KG+ + ++ E E ++G++ + D E+G E + + ++
Sbjct: 329 RSRSRERHRSRSRSRDRKGDRRDRDRER---EKENERGRRRDRD-YDKERGNEREKERER 384
Query: 160 DSKKGKKDAEKGK-DSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSK 218
++ K+ +G+ + ED+ +D+K+D K K S + E + +
Sbjct: 385 SRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSR-ERKHRSRSRSRN 443
Query: 219 KGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPS 278
GK+ + K+ K+ + K+E +K + + D+ ++K KK + PS
Sbjct: 444 AGKRSRSRSKE--------KSSKHKNESKEKSNKRSRSGSQGRTDS--VEKSKKREHSPS 493
Query: 279 STDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKD 326
S + K+ S K D+K + K + S ++++++ K+
Sbjct: 494 KEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKN 541
Score = 51.6 bits (122), Expect = 1e-06
Identities = 37/191 (19%), Positives = 89/191 (46%), Gaps = 6/191 (3%)
Query: 110 KAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKG---KK 166
K E G++ + ++ + E E ++ ++ SK+ + + +E+K KD ++ K+
Sbjct: 358 KENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKR 417
Query: 167 DAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKK 226
D++K K + E+ + ++ ++ + S+ + EK +K+ + S+
Sbjct: 418 DSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQG 477
Query: 227 GKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKD 286
DS + + + K++ K+ +K K D+K+ + K D+++ S + +S++
Sbjct: 478 RTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKD-QSDKHDRRRSQSIEQESQE 536
Query: 287 DVKKESKKDAT 297
K+ KD T
Sbjct: 537 --KQHKNKDET 545
Score = 51.2 bits (121), Expect = 1e-06
Identities = 33/201 (16%), Positives = 93/201 (46%), Gaps = 11/201 (5%)
Query: 158 KKDSKKGKKDAEKGKD-----SATESEDEKGGAKKDNKKDKKDSNKGK---DSATESEGE 209
KKD K+G ++ ++ + S S + ++ + G D E E E
Sbjct: 241 KKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKE 300
Query: 210 KGGTEKDSKKGKKDSKKGK--DSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEI 267
+ E+++K+ +K+ ++ + D +E + ++ E+ + KGD ++ KE
Sbjct: 301 RQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKEN 360
Query: 268 KKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDA 327
++G++ + + + ++ + ++E ++ +K+ + + + +K D ++ K+D+
Sbjct: 361 ERGRR-RDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDS 419
Query: 328 KKDAKKNAKKDEKKDAKKKGK 348
KK+ K + + ++ + + +
Sbjct: 420 KKEKKHSRSRSRERKHRSRSR 440
Score = 42.4 bits (98), Expect = 6e-04
Identities = 38/194 (19%), Positives = 82/194 (42%), Gaps = 9/194 (4%)
Query: 63 DEEQLRGDRRQPLWMYRSLMRISERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGEDKT 122
++E RG RR + R +ER +R + + EV+ K + K +D+
Sbjct: 357 EKENERGRRRDRDY---DKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDK--DDRR 411
Query: 123 TQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEK 182
+ D DS+ E K + S++ K + + K+ + K+ + K K+ + E +++
Sbjct: 412 HRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNA-GKRSRSRSKEKSSKHKNESKEKSNKR 470
Query: 183 GGAKKDNKKDKKDSNKGKD---SATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKA 239
+ + D + +K ++ S +S E+ K+ DSK D ++
Sbjct: 471 SRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSI 530
Query: 240 DEKKDEDGKKDANK 253
+++ E K+ ++
Sbjct: 531 EQESQEKQHKNKDE 544
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 80.1 bits (196), Expect = 3e-15
Identities = 68/248 (27%), Positives = 114/248 (45%), Gaps = 28/248 (11%)
Query: 115 GKKGEDKTTQKDTTDS----------ESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKG 164
GK ED TT D+ E K +G E GK+EK A+
Sbjct: 24 GKLSEDGTTVSPAADNPEMSGGGAPAEETKGTAGKAINEGPPTESGKQEKAPAEDGMSAE 83
Query: 165 KKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDS 224
+ G D + G K+D + + K + K+ T E G ++++K K++
Sbjct: 84 LQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKEETTVGSQEMTGRKEETKSEPKEA 143
Query: 225 KKGKDSAIELQAVKADEK--KDEDGKK-DANKGDESKD----AKKDAKEIKKGKKDKKKP 277
++ K+S + + KA+EK K E G+K DAN D+ + ++DAK + + ++K
Sbjct: 144 EE-KESTLASEKQKAEEKEAKPESGQKADANDRDKPEPKATVEEEDAKTASQEETGQRKE 202
Query: 278 SSTDSDSK---DDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKN 334
ST+ K ++ K ES+K +D K E + D K++AK AK++A DAK+
Sbjct: 203 CSTEPKEKATDEEAKAESQKAVVEDEAK-----AEPKEPDGKEEAKHGAKEEA--DAKEE 255
Query: 335 AKKDEKKD 342
A+ E+ +
Sbjct: 256 AEDAEEAE 263
Score = 53.9 bits (128), Expect = 2e-07
Identities = 49/231 (21%), Positives = 99/231 (42%), Gaps = 12/231 (5%)
Query: 101 PTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKD 160
PT + + + AE G E + + E+K + GK+ + + +K D +K+
Sbjct: 65 PTESGKQEKAPAEDGMSAE----LQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKE 120
Query: 161 SKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKG 220
G+ T+SE ++ K+ +K + K++ ES G+K K
Sbjct: 121 ETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPES-GQKADANDRDKPE 179
Query: 221 KKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSST 280
K + + +D+ Q K+ K+ +E+K + A + K + K+P
Sbjct: 180 PKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEP--- 236
Query: 281 DSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDA 331
D K++ K +K++A DAK+ A+ E E ++ +++ +K+ + A
Sbjct: 237 --DGKEEAKHGAKEEA--DAKEEAEDAEEAEPGSPSEEQEQDVEKEPEGGA 283
Score = 47.4 bits (111), Expect = 2e-05
Identities = 44/210 (20%), Positives = 85/210 (40%), Gaps = 26/210 (12%)
Query: 158 KKDSKKGK--KDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEK 215
K + K+GK +D +A E GGA + K + TES ++ +
Sbjct: 18 KMEQKEGKLSEDGTTVSPAADNPEMSGGGAPAEETKGTAGKAINEGPPTESGKQEKAPAE 77
Query: 216 DSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKK----GK 271
D + + A L VK + +++ GK+DA + +D +K+ + G+
Sbjct: 78 DGMSAELQGE-----ANGLDEVKVESQREAGGKEDAEAELKKEDGEKEETTVGSQEMTGR 132
Query: 272 KDKKKPSSTDSDSKDD-VKKESKKDATKDAKKVA--------------KKDTEKESADSK 316
K++ K +++ K+ + E +K K+AK + K E+E A +
Sbjct: 133 KEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPEPKATVEEEDAKTA 192
Query: 317 KDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
+ +K+ + K+ A +E K +K
Sbjct: 193 SQEETGQRKECSTEPKEKATDEEAKAESQK 222
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 78.6 bits (192), Expect = 8e-15
Identities = 57/223 (25%), Positives = 109/223 (48%), Gaps = 10/223 (4%)
Query: 84 ISERPSVYLAARRQPLKPTRTVE-VDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSK 142
IS R +V L Q + + + + +E K+ ++ +K + E + ++GKK+ K
Sbjct: 5 ISSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKK 64
Query: 143 KGKDIEKGKEEKLDAKKDSKKGKKDAEK-----GKDSATESEDEKGGAKKDNKKDKKDSN 197
K K E+GKE + K+ K+ K+ EK K+ ++G ++ KK++K+
Sbjct: 65 KRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERE 124
Query: 198 KGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKAD-EKKDEDGKKDANKGDE 256
+ E + +K +K K+ K++ ++GK + K + EKK E +K+ K E
Sbjct: 125 RENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERE 184
Query: 257 SK---DAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDA 296
K + KK+ K+ ++ KK++KK TD + V + ++ A
Sbjct: 185 RKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESA 227
Score = 78.6 bits (192), Expect = 8e-15
Identities = 52/208 (25%), Positives = 104/208 (50%), Gaps = 16/208 (7%)
Query: 125 KDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGG 184
K T ESE K+ +++ +K K E+ KE K + K KK +K E+GK+ + ++ +
Sbjct: 27 KPCTQRESERKKERREREKRKR-EREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
Query: 185 AKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKD 244
K+ +K+++ K K + +G E+ KK +K+ ++ ++++
Sbjct: 86 RKERREKERRKRKKEKKKRERKQ--RGRRERKKKKERKERER------------ENKQRR 131
Query: 245 EDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVA 304
E +K K K+ K++ + K+ +K KK+ ++ +KE KK+ + ++
Sbjct: 132 ERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRER 191
Query: 305 KKDTEKESADSKKDAKKNAKKDAKKDAK 332
KK+ +KE KK+ KK+ K D + D++
Sbjct: 192 KKERKKERR-KKKERKKDRKTDRQTDSQ 218
Score = 63.2 bits (152), Expect = 3e-10
Identities = 44/182 (24%), Positives = 94/182 (51%), Gaps = 20/182 (10%)
Query: 176 TESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKK----GKKDSKKGKDSA 231
T+ E E+ +++ +K K++ K E + E+G EK +K GK+ +K K+
Sbjct: 30 TQRESERKKERREREKRKREREK------ERKRERGKKEKKKRKKRERGKERERKRKER- 82
Query: 232 IELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSD------SK 285
E Q + EK+ KK+ K + + +++ K+ KK +K++++ + + K
Sbjct: 83 -EKQRKERREKERRKRKKEKKKRERKQRGRRERKK-KKERKERERENKQRRERKRKKRRK 140
Query: 286 DDVKKESKKDATKDAKKVAKKDTEKESADSKKDA-KKNAKKDAKKDAKKNAKKDEKKDAK 344
+KE K++ + ++ +K +KE + K++ +K KK+ ++ ++ KK+ KK+ +
Sbjct: 141 KKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERR 200
Query: 345 KK 346
KK
Sbjct: 201 KK 202
Score = 48.9 bits (115), Expect = 7e-06
Identities = 24/111 (21%), Positives = 60/111 (54%), Gaps = 1/111 (0%)
Query: 238 KADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDAT 297
+ E+K E +++ K + K+ K++ + K+ KK KK+ + + K +++ +K+
Sbjct: 32 RESERKKERREREKRKREREKERKRERGK-KEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 298 KDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
+ ++ KK+ +K + ++ KK+ K+ ++N ++ E+K K++ K
Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKK 141
Score = 39.7 bits (91), Expect = 0.004
Identities = 22/90 (24%), Positives = 47/90 (52%), Gaps = 7/90 (7%)
Query: 257 SKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSK 316
SK + E KK +++++K K + +KE K++ K KK KK + + K
Sbjct: 26 SKPCTQRESERKKERREREK-------RKREREKERKRERGKKEKKKRKKRERGKERERK 78
Query: 317 KDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
+ ++ +K+ ++ ++ KK++KK +K+
Sbjct: 79 RKEREKQRKERREKERRKRKKEKKKRERKQ 108
Score = 28.5 bits (62), Expect = 9.3
Identities = 14/45 (31%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Query: 303 VAKKDTEKESADSK-KDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
++K T++ES K + ++ K++ +K+ K+ K EKK KK+
Sbjct: 25 ISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKR 69
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 78.6 bits (192), Expect = 8e-15
Identities = 54/211 (25%), Positives = 101/211 (47%), Gaps = 15/211 (7%)
Query: 133 ELKQGKKDSKKGKDIEKGKEEKLDA--KKDSKKGKKDAEKGKDSATESEDEKGGAKKDNK 190
E+K+ ++ K G EEK++ KK+ +K ++ G +S+++ + K KK +
Sbjct: 43 EVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSC 102
Query: 191 KDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKD 250
+ S+ S++ S+ E +++ K+GK+ KK S Q+ + + + + K+
Sbjct: 103 RSSSSSSSSDSSSSSSDSE----DEEKKQGKRRKKKKNRSYKSSQS--STHESESESKES 156
Query: 251 ANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEK 310
K +SKD + K+++ K +KK D + ES + AKK K
Sbjct: 157 VKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKK-------K 209
Query: 311 ESADSKKDAKKNAKKDAKKDAKKNAKKDEKK 341
+ ++ AK+ KK KK KK++KK +KK
Sbjct: 210 RRCEEREQAKEKVKKKKKKQHKKHSKKKKKK 240
Score = 60.8 bits (146), Expect = 2e-09
Identities = 56/215 (26%), Positives = 90/215 (41%), Gaps = 42/215 (19%)
Query: 159 KDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSK 218
++ KK ++ + G + E E+ K N+ KK+ K ++ + K
Sbjct: 42 EEVKKQLENKKTGSKALAEFEE------KMNENWKKELEKSREKLLSGNESSSKKRERKK 95
Query: 219 KGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPS 278
K KK S + S+ D ++ +E K K+ K KK + K S
Sbjct: 96 KRKKKSCRSSSSS---------SSSDSSSSSSDSEDEEKKQGKRRKK--KKNRSYKSSQS 144
Query: 279 ST---DSDSKDDVKKESK-KDAT---KDAKKVAKKDTE------------------KESA 313
ST +S+SK+ VKK+ K KD T KD + ++KK + +E
Sbjct: 145 STHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDV 204
Query: 314 DSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
+KK + ++ AK+ KK KK KK +KKK K
Sbjct: 205 QAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKK 239
Score = 59.3 bits (142), Expect = 5e-09
Identities = 49/175 (28%), Positives = 76/175 (43%), Gaps = 15/175 (8%)
Query: 106 EVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGK 165
E SK E KK + K+ + ++ S S+ DS+ EEK K+ KK
Sbjct: 85 ESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSED--------EEKKQGKRRKKKKN 136
Query: 166 KDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSK 225
+ + + S ESE E + K KK K ++ K KD + S+ K + D K +S
Sbjct: 137 RSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKK-SYPDDKPLSSESS 195
Query: 226 KGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSST 280
D ++QA K ++ + K+ K + K KK +K K KKK S+
Sbjct: 196 SESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSK------KKKKKSGSS 244
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 78.2 bits (191), Expect = 1e-14
Identities = 73/318 (22%), Positives = 142/318 (44%), Gaps = 37/318 (11%)
Query: 65 EQLRGDRRQPLWM-------YRSLMRISERPSVYLAARRQPLK---------------PT 102
+QL + R W Y+ L+ + + +AA R+ L+ P
Sbjct: 365 QQLDAELRNTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLEGEECRIGFGPIPFSLPE 424
Query: 103 RTVEVDSKAAEIGKKGEDKTTQKDTTDSESEL-KQGKKDSKKGKDI--EKGKEEKLDAKK 159
++ S + I K E+K + ++ E+ + ++ ++++ +++ E+ KE K + K
Sbjct: 425 GLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGK 484
Query: 160 DSKKGKKDAEKGKDSATESE--DEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDS 217
+ + G+++ +G + T+S +E +K+ K K+ K A E E+ + +
Sbjct: 485 EEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEV 544
Query: 218 KKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKD-------AKEIKKG 270
K +K K+ A K+ EK++ + +++K K+ AK +K
Sbjct: 545 KSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKA 604
Query: 271 KKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKD 330
K K+ + + +++K VK+E+K A + + AK T KE A S + AK K++AK
Sbjct: 605 KSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPT-KEEAKSPEKAKSPEKEEAKSP 663
Query: 331 AKKNAKKDEKKDAKKKGK 348
K AK K +AK K
Sbjct: 664 EK--AKSPVKAEAKSPEK 679
Score = 77.8 bits (190), Expect = 1e-14
Identities = 76/257 (29%), Positives = 118/257 (45%), Gaps = 26/257 (10%)
Query: 96 RQPLKPTRTVEVDSKAAEIGK---KGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKE 152
+ P K V+ ++K+ E K K E KT +K ++S +K+ K +K K EK K
Sbjct: 703 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEK----AKSPVKEEAKSPEKAKSPEKAKT 758
Query: 153 EKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGG 212
LD K S + K A++ S + EK AK K++ K K K S + + +
Sbjct: 759 --LDVK--SPEAKTPAKEEARSPADKFPEK--AKSPVKEEVKSPEKAK-SPLKEDAKAPE 811
Query: 213 TEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDA---KEIKK 269
E K+ K K ++ E++ + +K +E+ K +E KD+KK+ KE K
Sbjct: 812 KEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPK 871
Query: 270 GKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKK 329
K ++KK + + + V E+KK+ +D KKV + E AK K+DAK
Sbjct: 872 PKVEEKKEPAVEKPKESKV--EAKKEEAEDKKKVPTPEKEAP-------AKVEVKEDAKP 922
Query: 330 DAKKNAKKDEKKDAKKK 346
K K E DAK K
Sbjct: 923 KEKTEVAKKEPDDAKAK 939
Score = 77.8 bits (190), Expect = 1e-14
Identities = 69/254 (27%), Positives = 119/254 (46%), Gaps = 24/254 (9%)
Query: 103 RTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSK 162
++ E + A E + DK +K + + E+K +K K+ K E+++ K++ K
Sbjct: 762 KSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVK 821
Query: 163 KGKKDAEKG-----KDSATESEDEKGGA--KKDNKKDKKDSNKGKDSATESEGEKGGTEK 215
K+ EK K+ ++E+EK A K + KKD K K+ A + E K E+
Sbjct: 822 SPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSK-----KEEAPKKEAPKPKVEE 876
Query: 216 DSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKK 275
K + +K K+S +E + +A++KK + + + K+DAK +K + KK
Sbjct: 877 ---KKEPAVEKPKESKVEAKKEEAEDKKKVPTPE--KEAPAKVEVKEDAKPKEKTEVAKK 931
Query: 276 KPSSTDSDSKDDVKKESKKDATKDAKKV----AKKDTEKESADSK-KDAKKNAKKDAKKD 330
+P D+ +K+ K KK+A + K AKK EK ++K K+ K K+ K
Sbjct: 932 EPD--DAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKP 989
Query: 331 AKKNAKKDEKKDAK 344
+ A+K D K
Sbjct: 990 KAEKAEKSSSTDQK 1003
Score = 77.4 bits (189), Expect = 2e-14
Identities = 70/242 (28%), Positives = 113/242 (46%), Gaps = 16/242 (6%)
Query: 116 KKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSA 175
K E KT K+ S ++ K S ++++ ++ K K+D+K +K+ K ++
Sbjct: 762 KSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVK 821
Query: 176 TESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQ 235
+ ++E+ + K+ K + + K AT EK KDSKK + K+ +E +
Sbjct: 822 SPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEK----KDSKKEEAPKKEAPKPKVEEK 877
Query: 236 AVKADEKKDEDGKKDANKGDESKDAKK--------DAK-EIKKGKKDKKKPSSTDSDSKD 286
A EK E K +A K +E++D KK AK E+K+ K K+K + D
Sbjct: 878 KEPAVEKPKE-SKVEAKK-EEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDD 935
Query: 287 DVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
KE K A K KKDT++E A K + K + AK+D K +K+ K A+K
Sbjct: 936 AKAKEPSKPAEKKEAAPEKKDTKEEKA-KKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKA 994
Query: 347 GK 348
K
Sbjct: 995 EK 996
Score = 76.6 bits (187), Expect = 3e-14
Identities = 70/266 (26%), Positives = 119/266 (44%), Gaps = 15/266 (5%)
Query: 93 AARRQPLKPTRTVEVDSKAAEIGK---KGEDKTTQKDTTDSESELKQGKKDSKKGKDIEK 149
A + P+K + K+ E K K E K+ +K + + E K +K K K
Sbjct: 616 AEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAK 675
Query: 150 GKEE-KLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEG 208
E+ K K ++K +K K+ A E K K++ K +K + K+ A E
Sbjct: 676 SPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEK 735
Query: 209 EKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIK 268
K ++++K +K K +++++ +A E+ + A+K E AK KE
Sbjct: 736 AKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEK--AKSPVKEEV 793
Query: 269 KGKKDKKKPSSTDSDS--KDDVKKESKKDATKDAKK---VAKKDTEKESADSKKDA--KK 321
K + K P D+ + K+ KKE K K+ +K V K+ K++ + K A K
Sbjct: 794 KSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKT 853
Query: 322 NAKKDAKKD--AKKNAKKDEKKDAKK 345
KKD+KK+ KK A K + ++ K+
Sbjct: 854 EEKKDSKKEEAPKKEAPKPKVEEKKE 879
Score = 73.9 bits (180), Expect = 2e-13
Identities = 65/264 (24%), Positives = 120/264 (45%), Gaps = 17/264 (6%)
Query: 96 RQPLKPTRTVEVDSKAAEIGKKGED-KTTQKDTTDSESELKQG-KKDSKKGKDIEKGKEE 153
+ P K + ++K+ K E K+ K+ S +E K K+++K +++ ++
Sbjct: 579 KSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKA 638
Query: 154 KLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGT 213
K K+++K +K K+ A E K K + K +K + K A E K
Sbjct: 639 KSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPV 698
Query: 214 EKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKD-AKKDAKEIKKGKK 272
++++K +K K+ A K+ EK K++A +++K K++AK +K K
Sbjct: 699 KEEAKSPEKAKSPVKEEA------KSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKS 752
Query: 273 DKKKPSST--DSDSKDDVKKESKKDATKDAKKVAK------KDTEKESADSKKDAKKNAK 324
+K + ++K K+E++ A K +K K EK + K+DAK K
Sbjct: 753 PEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEK 812
Query: 325 KDAKKDAKKNAKKDEKKDAKKKGK 348
+ KK+ K+ K+E+K + K K
Sbjct: 813 EIPKKEEVKSPVKEEEKPQEVKVK 836
Score = 73.6 bits (179), Expect = 3e-13
Identities = 68/264 (25%), Positives = 109/264 (41%), Gaps = 24/264 (9%)
Query: 98 PLKPTRTVEVDSKAA---EIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEK 154
P + + E ++K+ E E K+ +K+ S +E+K +K K+ K E
Sbjct: 505 PAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA 564
Query: 155 LDAKKDSKKGK---KDAEKGKDSATESEDEKGGAKKDNK-----KDKKDSNKGKDSATES 206
+K+ K K EK K A E AK K K++ S S +
Sbjct: 565 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE 624
Query: 207 EGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKD-AKKDAK 265
E + K +K K +K + K+ EK K++A +++K K +AK
Sbjct: 625 EAKSPAEVKSPEKAKSPTK---------EEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAK 675
Query: 266 EIKKGKKDKKKPSSTDSDSKDDVKKESKK-DATKDAKKVAKKDTEKESADSKKDAKKNAK 324
+K K K + + +K VK+E+K + K K K EK + K++AK K
Sbjct: 676 SPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEK 735
Query: 325 KDAKKDAKKNAKKDEKKDAKKKGK 348
AK K+ AK EK + +K K
Sbjct: 736 --AKSPVKEEAKSPEKAKSPEKAK 757
Score = 73.6 bits (179), Expect = 3e-13
Identities = 76/271 (28%), Positives = 117/271 (43%), Gaps = 24/271 (8%)
Query: 96 RQPLKPTRTVEVDSKAAEIGK---KGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKE 152
+ P K V+ ++K+ E K K E K+ +K + + E K +K K+ K E
Sbjct: 661 KSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPE 720
Query: 153 EKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGG 212
+ AK K+ K EK K E AK K D + E +
Sbjct: 721 K---AKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSP 777
Query: 213 TEKDSKKGKKDSKKGKDSAIELQA-VKADEKKDEDG--KKDANKG---DESKDAKKDAKE 266
+K +K K K+ S + ++ +K D K E KK+ K +E K + KE
Sbjct: 778 ADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKE 837
Query: 267 IKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSK-KDAKKNAKK 325
K +++K P++ ++ K D KKE +A K K + +KE A K K++K AKK
Sbjct: 838 PPKKAEEEKAPATPKTEEKKDSKKE---EAPKKEAPKPKVEEKKEPAVEKPKESKVEAKK 894
Query: 326 DAKKDAKK--------NAKKDEKKDAKKKGK 348
+ +D KK AK + K+DAK K K
Sbjct: 895 EEAEDKKKVPTPEKEAPAKVEVKEDAKPKEK 925
Score = 72.4 bits (176), Expect = 6e-13
Identities = 67/232 (28%), Positives = 119/232 (51%), Gaps = 23/232 (9%)
Query: 117 KGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKG-KEEKLDAKKDSKKGKKDAEKGKDSA 175
K E K+ +K + + + K +K+ K ++++ KEE+ + K+ K AE+ K A
Sbjct: 790 KEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPA 849
Query: 176 TESEDEKGGAKKDNK----------KDKKDS--NKGKDSATESEGEKGGTEKDSKKGKKD 223
T +EK +KK+ ++KK+ K K+S E++ E+ +K +K+
Sbjct: 850 TPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKE 909
Query: 224 SK---KGKDSAIELQAVKADEKKDEDGK-KDANKGDESKDA---KKDAKEIKKGKKDKKK 276
+ + K+ A + + +K+ +D K K+ +K E K+A KKD KE +K KK ++K
Sbjct: 910 APAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKE-EKAKKPEEK 968
Query: 277 PSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAK 328
P T++ +K+D K SK+ + A+K A+K + + DSK K K AK
Sbjct: 969 P-KTEAKAKEDDKTLSKEPSKPKAEK-AEKSSSTDQKDSKPPEKATEDKAAK 1018
Score = 68.9 bits (167), Expect = 6e-12
Identities = 62/257 (24%), Positives = 108/257 (42%), Gaps = 13/257 (5%)
Query: 93 AARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKE 152
A + P K V+ ++K+ E K+ K+ S +E+K +K K+ K E
Sbjct: 596 AEAKSPEKAKSPVKEEAKSP-----AEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPE 650
Query: 153 E-KLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKG 211
+ K K+++K +K K A E K K + K +K + K+ A E K
Sbjct: 651 KAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKS 710
Query: 212 GTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGK 271
++++K +K K+ A K EK K++A +++K +K AK +
Sbjct: 711 PVKEEAKSPEKAKSPVKEEA------KTPEKAKSPVKEEAKSPEKAKSPEK-AKTLDVKS 763
Query: 272 KDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDA 331
+ K P+ ++ S D E K K+ K +K D+K K+ KK+ K
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP 823
Query: 332 KKNAKKDEKKDAKKKGK 348
K +K ++ K+ K
Sbjct: 824 VKEEEKPQEVKVKEPPK 840
Score = 68.2 bits (165), Expect = 1e-11
Identities = 66/258 (25%), Positives = 116/258 (44%), Gaps = 22/258 (8%)
Query: 112 AEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGK-DIEKGKEEKLDAKKDSKKGK--KDA 168
AE+ + K+ K+ S E K +K+ K +++ ++ K AK+++K K
Sbjct: 542 AEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSP 601
Query: 169 EKGKDSATESEDEKGGAKKDNKKDKKDSNKGKD-----SATESEGEKGGTEKDSKKGKKD 223
EK K E AK K++ K + K S T+ E + K +K +
Sbjct: 602 EKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAK 661
Query: 224 SKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKD-AKKDAKEIKKGKKDKKKPSSTDS 282
S + S ++ +A K+ EK K +A +++K K++AK +K K K+ + +
Sbjct: 662 SPEKAKSPVKAEA-KSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPE 720
Query: 283 DSKDDVKKESK--KDATKDAKKVAKKDTEKESADSKK-------DAKKNAKKDAKKDAKK 333
+K VK+E+K + A K+ AK + +S + K +AK AK++A+ A K
Sbjct: 721 KAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADK 780
Query: 334 ---NAKKDEKKDAKKKGK 348
AK K++ K K
Sbjct: 781 FPEKAKSPVKEEVKSPEK 798
Score = 41.6 bits (96), Expect = 0.001
Identities = 38/122 (31%), Positives = 53/122 (43%), Gaps = 25/122 (20%)
Query: 96 RQPLKPTRTVEV------DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEK 149
++ KP EV D+KA E K E K + D++ E + KK +K K K
Sbjct: 917 KEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEE--KAKKPEEKPKTEAK 974
Query: 150 GKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGE 209
KE+ K+ K K AEK A+K + D+KDS K + ATE +
Sbjct: 975 AKEDDKTLSKEPSKPK--AEK--------------AEKSSSTDQKDS-KPPEKATEDKAA 1017
Query: 210 KG 211
KG
Sbjct: 1018 KG 1019
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 77.8 bits (190), Expect = 1e-14
Identities = 70/312 (22%), Positives = 141/312 (45%), Gaps = 18/312 (5%)
Query: 38 PKPQRPGTKRRSKPSQIRDNTVSIIDEEQLRGDRRQPLWMYRSLMRISERPSVYLAARRQ 97
PK + P K + K + II+E ++ ++ + M +L I+E +V + ++
Sbjct: 439 PKVEAPKLKVQHKFVE------EIIEETKVEDEKSE---MEEALTAITEELAVSMKEEKK 489
Query: 98 PLKPTRTVEVDSKAAEIG-KKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLD 156
+ E +++ E+ KK K T + + E E ++ + ++ ++ E K ++ +
Sbjct: 490 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE 549
Query: 157 AKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKD 216
K+G + E+G+ E+E E G + + K++KK K ++ AT+ E +
Sbjct: 550 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK 609
Query: 217 SKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKK 276
+K K K S +E + K+ K +K + +S +K + K ++K
Sbjct: 610 PEKAKSPVPK---SPVE-EKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKG 665
Query: 277 PSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAK 336
S SK V++++K K + AK E + K++ +K K+A K+ K K
Sbjct: 666 KSPV---SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEV-KEAPKEEKVEKK 721
Query: 337 KDEKKDAKKKGK 348
+++ KD +K K
Sbjct: 722 EEKPKDVPEKKK 733
Score = 67.8 bits (164), Expect = 1e-11
Identities = 67/260 (25%), Positives = 115/260 (44%), Gaps = 37/260 (14%)
Query: 119 EDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDA-------EKG 171
E+ T+ + E+E K+ KK +K +++ +E DAK + + K EKG
Sbjct: 567 EEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKG 626
Query: 172 KDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSA 231
K +S E+ G K ++ KGK +S E+ G SK ++ K S
Sbjct: 627 KSPVPKSPVEEKGKSPVPKSPVEE--KGKSPVPKSPVEEKGKSPVSKSPVEEKAK---SP 681
Query: 232 IELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKK-KPSSTDSDSKDDVKK 290
+ V+ + K E GK + K +E K+ K+ KE K KK++K K ++ VK+
Sbjct: 682 VPKSPVEEAKSKAEVGKGE-QKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKE 740
Query: 291 ESKKDA--------------TKDAKKVAKKDTEKESA---------DSKKDAKKNAKKDA 327
E+ + TK+ K +++ EKE A S K AK + K+D
Sbjct: 741 EAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDI 800
Query: 328 KKDAKKNAKKDEKKDAKKKG 347
+ + K++ +++ K+KG
Sbjct: 801 AVNGEVEGKEEVEQETKEKG 820
Score = 56.6 bits (135), Expect = 3e-08
Identities = 58/233 (24%), Positives = 102/233 (43%), Gaps = 25/233 (10%)
Query: 101 PTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKD 160
P VE AE+GK + + +K+ ++ E K KK+ +K KD+ + K+ + K++
Sbjct: 683 PKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKE-EKPKDVPEKKKAESPVKEE 741
Query: 161 SKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKG 220
+ K E E ++ G +K+K+ ++ GE G E+ S KG
Sbjct: 742 AVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKE----------KAGGEGGSEEEGSDKG 791
Query: 221 KKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKD------AKEIKKGKKDK 274
K S+K +D A+ + V+ E+ +++ K+ + +E K + A E K G K +
Sbjct: 792 AKGSRK-EDIAVNGE-VEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSE 849
Query: 275 KKPSST------DSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKK 321
+K T S+ D K K T K ++T +E S K +K
Sbjct: 850 EKVVVTKTVEKITSEGGDGATKYITKSVTVTQKVEEHEETFEEKLVSTKKVEK 902
Score = 38.5 bits (88), Expect = 0.009
Identities = 51/212 (24%), Positives = 84/212 (39%), Gaps = 30/212 (14%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
+ K AE K E+ + T ++ K+ ++GK +++ KE++
Sbjct: 730 EKKKAESPVK-EEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKE------------- 775
Query: 168 AEKGKDSATESEDEKGGAKKDNKKD--KKDSNKGKDSATESEGEKGGTEKDSKKGKKDSK 225
+ G + +E E GAK K+D +GK+ + EKG G+++ K
Sbjct: 776 -KAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKG-------SGREEEK 827
Query: 226 KGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKG--KKDKKKPSSTDSD 283
+ ++L ADEKK G K K +K +K E G K K + T
Sbjct: 828 GVVTNGLDLS--PADEKK--GGDKSEEKVVVTKTVEKITSEGGDGATKYITKSVTVTQKV 883
Query: 284 SKDDVKKESKKDATKDAKKVAKKDTEKESADS 315
+ + E K +TK +KV KE S
Sbjct: 884 EEHEETFEEKLVSTKKVEKVTSHAIVKEVTQS 915
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 77.8 bits (190), Expect = 1e-14
Identities = 70/312 (22%), Positives = 141/312 (45%), Gaps = 18/312 (5%)
Query: 38 PKPQRPGTKRRSKPSQIRDNTVSIIDEEQLRGDRRQPLWMYRSLMRISERPSVYLAARRQ 97
PK + P K + K + II+E ++ ++ + M +L I+E +V + ++
Sbjct: 63 PKVEAPKLKVQHKFVE------EIIEETKVEDEKSE---MEEALTAITEELAVSMKEEKK 113
Query: 98 PLKPTRTVEVDSKAAEIG-KKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLD 156
+ E +++ E+ KK K T + + E E ++ + ++ ++ E K ++ +
Sbjct: 114 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE 173
Query: 157 AKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKD 216
K+G + E+G+ E+E E G + + K++KK K ++ AT+ E +
Sbjct: 174 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK 233
Query: 217 SKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKK 276
+K K K S +E + K+ K +K + +S +K + K ++K
Sbjct: 234 PEKAKSPVPK---SPVE-EKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKG 289
Query: 277 PSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAK 336
S SK V++++K K + AK E + K++ +K K+A K+ K K
Sbjct: 290 KSPV---SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEV-KEAPKEEKVEKK 345
Query: 337 KDEKKDAKKKGK 348
+++ KD +K K
Sbjct: 346 EEKPKDVPEKKK 357
Score = 67.8 bits (164), Expect = 1e-11
Identities = 67/260 (25%), Positives = 115/260 (44%), Gaps = 37/260 (14%)
Query: 119 EDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDA-------EKG 171
E+ T+ + E+E K+ KK +K +++ +E DAK + + K EKG
Sbjct: 191 EEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKG 250
Query: 172 KDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSA 231
K +S E+ G K ++ KGK +S E+ G SK ++ K S
Sbjct: 251 KSPVPKSPVEEKGKSPVPKSPVEE--KGKSPVPKSPVEEKGKSPVSKSPVEEKAK---SP 305
Query: 232 IELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKK-KPSSTDSDSKDDVKK 290
+ V+ + K E GK + K +E K+ K+ KE K KK++K K ++ VK+
Sbjct: 306 VPKSPVEEAKSKAEVGKGE-QKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKE 364
Query: 291 ESKKDA--------------TKDAKKVAKKDTEKESA---------DSKKDAKKNAKKDA 327
E+ + TK+ K +++ EKE A S K AK + K+D
Sbjct: 365 EAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDI 424
Query: 328 KKDAKKNAKKDEKKDAKKKG 347
+ + K++ +++ K+KG
Sbjct: 425 AVNGEVEGKEEVEQETKEKG 444
Score = 56.6 bits (135), Expect = 3e-08
Identities = 58/233 (24%), Positives = 102/233 (43%), Gaps = 25/233 (10%)
Query: 101 PTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKD 160
P VE AE+GK + + +K+ ++ E K KK+ +K KD+ + K+ + K++
Sbjct: 307 PKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKE-EKPKDVPEKKKAESPVKEE 365
Query: 161 SKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKG 220
+ K E E ++ G +K+K+ ++ GE G E+ S KG
Sbjct: 366 AVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKE----------KAGGEGGSEEEGSDKG 415
Query: 221 KKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKD------AKEIKKGKKDK 274
K S+K +D A+ + V+ E+ +++ K+ + +E K + A E K G K +
Sbjct: 416 AKGSRK-EDIAVNGE-VEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSE 473
Query: 275 KKPSST------DSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKK 321
+K T S+ D K K T K ++T +E S K +K
Sbjct: 474 EKVVVTKTVEKITSEGGDGATKYITKSVTVTQKVEEHEETFEEKLVSTKKVEK 526
Score = 38.5 bits (88), Expect = 0.009
Identities = 51/212 (24%), Positives = 84/212 (39%), Gaps = 30/212 (14%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
+ K AE K E+ + T ++ K+ ++GK +++ KE++
Sbjct: 354 EKKKAESPVK-EEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKE------------- 399
Query: 168 AEKGKDSATESEDEKGGAKKDNKKD--KKDSNKGKDSATESEGEKGGTEKDSKKGKKDSK 225
+ G + +E E GAK K+D +GK+ + EKG G+++ K
Sbjct: 400 -KAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKG-------SGREEEK 451
Query: 226 KGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKG--KKDKKKPSSTDSD 283
+ ++L ADEKK G K K +K +K E G K K + T
Sbjct: 452 GVVTNGLDLS--PADEKK--GGDKSEEKVVVTKTVEKITSEGGDGATKYITKSVTVTQKV 507
Query: 284 SKDDVKKESKKDATKDAKKVAKKDTEKESADS 315
+ + E K +TK +KV KE S
Sbjct: 508 EEHEETFEEKLVSTKKVEKVTSHAIVKEVTQS 539
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 77.8 bits (190), Expect = 1e-14
Identities = 57/256 (22%), Positives = 123/256 (48%), Gaps = 17/256 (6%)
Query: 102 TRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSK---------KGKDIEKGKE 152
+R+ + D + ++ K K+ ++ + S S + +KD++ K KD EK +E
Sbjct: 341 SRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERE 400
Query: 153 EKLDAKKDSKKGK-KDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKG 211
+ + +K+ ++GK KD +K ++ E + EK ++ K+ +KD +K K+ + E E+
Sbjct: 401 REKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER- 459
Query: 212 GTEKD-SKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKG 270
EKD SK+ + KK K S ++ A + ++ + S+ + + + K
Sbjct: 460 --EKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR--RSRSSSRSPRTSKTI 515
Query: 271 KKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKD 330
K+ + S S +K D K+E ++D + ++ ++ T + + +D K+ +K++
Sbjct: 516 KRKSSRSPSPRSRNKKDKKREKERDHISE-RRERERSTSMRKSSNDRDGKEKLEKNSTSL 574
Query: 331 AKKNAKKDEKKDAKKK 346
+K K+ K+
Sbjct: 575 KEKEHNKEPDSSVSKE 590
Score = 72.8 bits (177), Expect = 4e-13
Identities = 44/195 (22%), Positives = 92/195 (47%), Gaps = 8/195 (4%)
Query: 155 LDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTE 214
+ A + + GK + KG S + + + + K + + K+ +K + + S +
Sbjct: 289 ISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHR---SRSHNRSRSRQ 345
Query: 215 KDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDK 274
KD ++ K KK S ++ +D+ +KD + + K+ K+ K+ +++K
Sbjct: 346 KDRRRSKSPHKKRSKSRERRKSRSRSHSRDK--RKDTREKIKEKERVKEKDREKEREREK 403
Query: 275 KKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKE---SADSKKDAKKNAKKDAKKDA 331
++ + D KE +KD KD +K +++ EKE D +K+ +++ +K+ +KD
Sbjct: 404 EREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDR 463
Query: 332 KKNAKKDEKKDAKKK 346
K + KKD K +
Sbjct: 464 SKEIDEKRKKDKKSR 478
Score = 71.2 bits (173), Expect = 1e-12
Identities = 53/234 (22%), Positives = 116/234 (49%), Gaps = 12/234 (5%)
Query: 109 SKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDA 168
S+++ ++ K + S + + +KD ++ K K K K ++ S+
Sbjct: 316 SRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK-KRSKSRERRKSRSRSHSR 374
Query: 169 EKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGK 228
+K KD+ + ++++ +KD +K+++ ++ E E E+G + K+ +KD +K K
Sbjct: 375 DKRKDTREKIKEKERVKEKDREKERE-----REKEREKEKERGKNKDRDKEREKDREKDK 429
Query: 229 DSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEI-KKGKKDKKKPSSTDSDSKDD 287
+ E + K + +KD D +K+ + E + K +KEI +K KKDKK S T S +
Sbjct: 430 EKDREREREK-EHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK--SRTPPRSYNA 486
Query: 288 VKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKK 341
++ + ++++ ++ + + + SK +K+++ + + K KK EK+
Sbjct: 487 SRR--SRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE 538
Score = 70.9 bits (172), Expect = 2e-12
Identities = 54/257 (21%), Positives = 115/257 (44%), Gaps = 25/257 (9%)
Query: 105 VEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKG 164
+E +S + K G ++ + + S S+ +K S+ K + +KD ++
Sbjct: 293 IEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQS-KHRSRSHNRSRSRQKDRRRS 351
Query: 165 KKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDS 224
K +K S + +D +KD ++ K K+ E + EK + ++ +K+
Sbjct: 352 KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKER 411
Query: 225 KKGKDSAIELQAVKADEKKDEDGKKDANKGDE---SKDAKKDAKEIKKGKKDKKKPSSTD 281
K KD D+++++D +KD K E K+ +KD + K+ ++DK+K D
Sbjct: 412 GKNKD---------RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 462
Query: 282 -SDSKDDVKKESKKDAT-----------KDAKKVAKKDTEKESADSKKDAKKNAKKDAKK 329
S D+ +K+ KK T + + + ++ + S+ S + +K +K ++
Sbjct: 463 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 522
Query: 330 DAKKNAKKDEKKDAKKK 346
+ ++ K +KK K++
Sbjct: 523 PSPRSRNKKDKKREKER 539
Score = 67.0 bits (162), Expect = 2e-11
Identities = 53/220 (24%), Positives = 100/220 (45%), Gaps = 21/220 (9%)
Query: 117 KGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGK---------KD 167
K +++ +KD K+ +K+ ++GK+ ++ KE + D +KD +K + KD
Sbjct: 385 KEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKD 444
Query: 168 --AEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSK 225
EK K+ E E EK +K+ ++K KKD K S T S ++ +
Sbjct: 445 RDKEKEKEQDKEKEREKDRSKEIDEKRKKD----KKSRTPPRSYNASRRSRSSSRERRRR 500
Query: 226 KGKDSAIELQAVKADEKKD--EDGKKDANKGDESKDAKKD--AKEIKKGKKDKKKPSSTD 281
+ + S+ + K ++K + NK D+ ++ ++D ++ ++ + + SS D
Sbjct: 501 RSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSND 560
Query: 282 SDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKK 321
D K+ ++K S K+ K KE D KDA +
Sbjct: 561 RDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDD--KDAPR 598
Score = 65.9 bits (159), Expect = 5e-11
Identities = 42/216 (19%), Positives = 92/216 (42%), Gaps = 6/216 (2%)
Query: 133 ELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKD 192
E + GK + +KG K ++ SK + + S + +KD ++
Sbjct: 294 EPESGKSNERKGGRSRSHTRSK--SRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRS 351
Query: 193 KKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDAN 252
K K S + +D +K ++ K K+ E K EK+ E K+
Sbjct: 352 KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE----KDREKEREREKEREK 407
Query: 253 KGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKES 312
+ + K+ +D + K +KDK+K + + + + ++ +K+ +D +K +KD KE
Sbjct: 408 EKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEI 467
Query: 313 ADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
+ +K KK+ +A + ++ ++ +++ +
Sbjct: 468 DEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSR 503
Score = 42.0 bits (97), Expect = 8e-04
Identities = 29/132 (21%), Positives = 64/132 (48%), Gaps = 4/132 (3%)
Query: 219 KGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPS 278
K ++++ +AIE ++ K++E+K G+ ++ +S+ + K K+ + + S
Sbjct: 280 KRVREAQSFISAAIEPESGKSNERKG--GRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRS 337
Query: 279 STDSDSKDDVKKESKKDATKDAK--KVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAK 336
S S+ ++ SK K +K + K + S D +KD ++ K+ + K K
Sbjct: 338 HNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREK 397
Query: 337 KDEKKDAKKKGK 348
+ E++ ++K K
Sbjct: 398 EREREKEREKEK 409
Score = 36.2 bits (82), Expect = 0.045
Identities = 39/197 (19%), Positives = 78/197 (39%), Gaps = 48/197 (24%)
Query: 110 KAAEIGK-KGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKK-- 166
K E GK K DK +KD + + ++ +++ + KD +K KE++ D +K+ +K +
Sbjct: 407 KEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKE 466
Query: 167 -DAEKGKDSATESEDEKGGAKKD------------------------------------- 188
D ++ KD + + A +
Sbjct: 467 IDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPR 526
Query: 189 --NKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKD-- 244
NKKDKK + + E E+ + + S + +K + ++ L+ + +++ D
Sbjct: 527 SRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSS 586
Query: 245 ---EDGKKDANKGDESK 258
E KDA + +E+K
Sbjct: 587 VSKEVDDKDAPRTEENK 603
Score = 35.0 bits (79), Expect = 0.100
Identities = 31/166 (18%), Positives = 66/166 (39%), Gaps = 19/166 (11%)
Query: 106 EVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSK--------KGKDIEKGKEEKLDA 157
E D + ++ ++K +KD + E ++ K S+ + +E +
Sbjct: 442 EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR 501
Query: 158 KKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDK-------KDSNKGKDSATESEGEK 210
+ S + + ++ K ++ S + KKD K++K + + S +S ++
Sbjct: 502 SRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDR 561
Query: 211 GGTEKDSKKG----KKDSKKGKDSAIELQAVKADEKKDEDGKKDAN 252
G EK K +K+ K DS++ + D + E+ K N
Sbjct: 562 DGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHN 607
Score = 29.6 bits (65), Expect = 4.2
Identities = 29/159 (18%), Positives = 64/159 (40%), Gaps = 7/159 (4%)
Query: 46 KRRSKPSQIRDNTVSIIDEEQLRGDR-RQPLWMYRSLMRI--SERPSVYLAARRQPLKPT 102
K + K + + IDE++ + + R P Y + R S R +R P
Sbjct: 451 KEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPR 510
Query: 103 RTVEVDSKAAEI----GKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAK 158
+ + K++ + +DK +K+ ++ + S + ++ +EKL+
Sbjct: 511 TSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKN 570
Query: 159 KDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSN 197
S K K+ ++ S ++ D+K + + K + + N
Sbjct: 571 STSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGN 609
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 77.8 bits (190), Expect = 1e-14
Identities = 57/256 (22%), Positives = 123/256 (48%), Gaps = 17/256 (6%)
Query: 102 TRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSK---------KGKDIEKGKE 152
+R+ + D + ++ K K+ ++ + S S + +KD++ K KD EK +E
Sbjct: 225 SRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERE 284
Query: 153 EKLDAKKDSKKGK-KDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKG 211
+ + +K+ ++GK KD +K ++ E + EK ++ K+ +KD +K K+ + E E+
Sbjct: 285 REKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER- 343
Query: 212 GTEKD-SKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKG 270
EKD SK+ + KK K S ++ A + ++ + S+ + + + K
Sbjct: 344 --EKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR--RSRSSSRSPRTSKTI 399
Query: 271 KKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKD 330
K+ + S S +K D K+E ++D + ++ ++ T + + +D K+ +K++
Sbjct: 400 KRKSSRSPSPRSRNKKDKKREKERDHISE-RRERERSTSMRKSSNDRDGKEKLEKNSTSL 458
Query: 331 AKKNAKKDEKKDAKKK 346
+K K+ K+
Sbjct: 459 KEKEHNKEPDSSVSKE 474
Score = 72.8 bits (177), Expect = 4e-13
Identities = 44/195 (22%), Positives = 92/195 (47%), Gaps = 8/195 (4%)
Query: 155 LDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTE 214
+ A + + GK + KG S + + + + K + + K+ +K + + S +
Sbjct: 173 ISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHR---SRSHNRSRSRQ 229
Query: 215 KDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDK 274
KD ++ K KK S ++ +D+ +KD + + K+ K+ K+ +++K
Sbjct: 230 KDRRRSKSPHKKRSKSRERRKSRSRSHSRDK--RKDTREKIKEKERVKEKDREKEREREK 287
Query: 275 KKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKE---SADSKKDAKKNAKKDAKKDA 331
++ + D KE +KD KD +K +++ EKE D +K+ +++ +K+ +KD
Sbjct: 288 EREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDR 347
Query: 332 KKNAKKDEKKDAKKK 346
K + KKD K +
Sbjct: 348 SKEIDEKRKKDKKSR 362
Score = 71.2 bits (173), Expect = 1e-12
Identities = 53/234 (22%), Positives = 116/234 (49%), Gaps = 12/234 (5%)
Query: 109 SKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDA 168
S+++ ++ K + S + + +KD ++ K K K K ++ S+
Sbjct: 200 SRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK-KRSKSRERRKSRSRSHSR 258
Query: 169 EKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGK 228
+K KD+ + ++++ +KD +K+++ ++ E E E+G + K+ +KD +K K
Sbjct: 259 DKRKDTREKIKEKERVKEKDREKERE-----REKEREKEKERGKNKDRDKEREKDREKDK 313
Query: 229 DSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEI-KKGKKDKKKPSSTDSDSKDD 287
+ E + K + +KD D +K+ + E + K +KEI +K KKDKK S T S +
Sbjct: 314 EKDREREREK-EHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK--SRTPPRSYNA 370
Query: 288 VKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKK 341
++ + ++++ ++ + + + SK +K+++ + + K KK EK+
Sbjct: 371 SRR--SRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE 422
Score = 70.9 bits (172), Expect = 2e-12
Identities = 54/257 (21%), Positives = 115/257 (44%), Gaps = 25/257 (9%)
Query: 105 VEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKG 164
+E +S + K G ++ + + S S+ +K S+ K + +KD ++
Sbjct: 177 IEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQS-KHRSRSHNRSRSRQKDRRRS 235
Query: 165 KKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDS 224
K +K S + +D +KD ++ K K+ E + EK + ++ +K+
Sbjct: 236 KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKER 295
Query: 225 KKGKDSAIELQAVKADEKKDEDGKKDANKGDE---SKDAKKDAKEIKKGKKDKKKPSSTD 281
K KD D+++++D +KD K E K+ +KD + K+ ++DK+K D
Sbjct: 296 GKNKD---------RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 346
Query: 282 -SDSKDDVKKESKKDAT-----------KDAKKVAKKDTEKESADSKKDAKKNAKKDAKK 329
S D+ +K+ KK T + + + ++ + S+ S + +K +K ++
Sbjct: 347 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 406
Query: 330 DAKKNAKKDEKKDAKKK 346
+ ++ K +KK K++
Sbjct: 407 PSPRSRNKKDKKREKER 423
Score = 67.0 bits (162), Expect = 2e-11
Identities = 53/220 (24%), Positives = 100/220 (45%), Gaps = 21/220 (9%)
Query: 117 KGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGK---------KD 167
K +++ +KD K+ +K+ ++GK+ ++ KE + D +KD +K + KD
Sbjct: 269 KEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKD 328
Query: 168 --AEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSK 225
EK K+ E E EK +K+ ++K KKD K S T S ++ +
Sbjct: 329 RDKEKEKEQDKEKEREKDRSKEIDEKRKKD----KKSRTPPRSYNASRRSRSSSRERRRR 384
Query: 226 KGKDSAIELQAVKADEKKD--EDGKKDANKGDESKDAKKD--AKEIKKGKKDKKKPSSTD 281
+ + S+ + K ++K + NK D+ ++ ++D ++ ++ + + SS D
Sbjct: 385 RSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSND 444
Query: 282 SDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKK 321
D K+ ++K S K+ K KE D KDA +
Sbjct: 445 RDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDD--KDAPR 482
Score = 65.9 bits (159), Expect = 5e-11
Identities = 42/216 (19%), Positives = 92/216 (42%), Gaps = 6/216 (2%)
Query: 133 ELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKD 192
E + GK + +KG K ++ SK + + S + +KD ++
Sbjct: 178 EPESGKSNERKGGRSRSHTRSK--SRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRS 235
Query: 193 KKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDAN 252
K K S + +D +K ++ K K+ E K EK+ E K+
Sbjct: 236 KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE----KDREKEREREKEREK 291
Query: 253 KGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKES 312
+ + K+ +D + K +KDK+K + + + + ++ +K+ +D +K +KD KE
Sbjct: 292 EKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEI 351
Query: 313 ADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
+ +K KK+ +A + ++ ++ +++ +
Sbjct: 352 DEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSR 387
Score = 42.0 bits (97), Expect = 8e-04
Identities = 29/132 (21%), Positives = 64/132 (48%), Gaps = 4/132 (3%)
Query: 219 KGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPS 278
K ++++ +AIE ++ K++E+K G+ ++ +S+ + K K+ + + S
Sbjct: 164 KRVREAQSFISAAIEPESGKSNERKG--GRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRS 221
Query: 279 STDSDSKDDVKKESKKDATKDAK--KVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAK 336
S S+ ++ SK K +K + K + S D +KD ++ K+ + K K
Sbjct: 222 HNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREK 281
Query: 337 KDEKKDAKKKGK 348
+ E++ ++K K
Sbjct: 282 EREREKEREKEK 293
Score = 36.2 bits (82), Expect = 0.045
Identities = 39/197 (19%), Positives = 78/197 (39%), Gaps = 48/197 (24%)
Query: 110 KAAEIGK-KGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKK-- 166
K E GK K DK +KD + + ++ +++ + KD +K KE++ D +K+ +K +
Sbjct: 291 KEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKE 350
Query: 167 -DAEKGKDSATESEDEKGGAKKD------------------------------------- 188
D ++ KD + + A +
Sbjct: 351 IDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPR 410
Query: 189 --NKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKD-- 244
NKKDKK + + E E+ + + S + +K + ++ L+ + +++ D
Sbjct: 411 SRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSS 470
Query: 245 ---EDGKKDANKGDESK 258
E KDA + +E+K
Sbjct: 471 VSKEVDDKDAPRTEENK 487
Score = 35.0 bits (79), Expect = 0.100
Identities = 31/166 (18%), Positives = 66/166 (39%), Gaps = 19/166 (11%)
Query: 106 EVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSK--------KGKDIEKGKEEKLDA 157
E D + ++ ++K +KD + E ++ K S+ + +E +
Sbjct: 326 EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR 385
Query: 158 KKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDK-------KDSNKGKDSATESEGEK 210
+ S + + ++ K ++ S + KKD K++K + + S +S ++
Sbjct: 386 SRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDR 445
Query: 211 GGTEKDSKKG----KKDSKKGKDSAIELQAVKADEKKDEDGKKDAN 252
G EK K +K+ K DS++ + D + E+ K N
Sbjct: 446 DGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHN 491
Score = 29.6 bits (65), Expect = 4.2
Identities = 29/159 (18%), Positives = 64/159 (40%), Gaps = 7/159 (4%)
Query: 46 KRRSKPSQIRDNTVSIIDEEQLRGDR-RQPLWMYRSLMRI--SERPSVYLAARRQPLKPT 102
K + K + + IDE++ + + R P Y + R S R +R P
Sbjct: 335 KEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPR 394
Query: 103 RTVEVDSKAAEI----GKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAK 158
+ + K++ + +DK +K+ ++ + S + ++ +EKL+
Sbjct: 395 TSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKN 454
Query: 159 KDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSN 197
S K K+ ++ S ++ D+K + + K + + N
Sbjct: 455 STSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGN 493
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 77.4 bits (189), Expect = 2e-14
Identities = 61/205 (29%), Positives = 95/205 (46%), Gaps = 9/205 (4%)
Query: 133 ELKQGKKDSKKGKDIEKGKEEKLDA--KKDSKKGKKDAEKGKDSATESEDEKGGAKKDNK 190
E+K+ + KKG EEK++ KK+ +K ++ G +S+++ K KK+ K
Sbjct: 33 EVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRK---KKEKK 89
Query: 191 KDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKD 250
K + S+ S+ S ++D K+GK+ KK S ++ ++ + D K
Sbjct: 90 KSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSET--ESDSKDS 147
Query: 251 ANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEK 310
K +SKD + K+I KG K+K S D + ES+ AKK K E+
Sbjct: 148 LKKKKKSKDGTEKEKDI-KGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKK-KKSSEER 205
Query: 311 ESADSKKDAKKNAKKDAKKDAKKNA 335
E A K KK KK +KK KK A
Sbjct: 206 EKATEKTKKKKKHKKHSKKKKKKAA 230
Score = 73.6 bits (179), Expect = 3e-13
Identities = 58/214 (27%), Positives = 91/214 (42%), Gaps = 8/214 (3%)
Query: 100 KPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKK----GKDIEKGKEEKL 155
+P T E + E KKG + + +E+ K+ +K +K + K ++ K
Sbjct: 26 RPRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKK 85
Query: 156 DAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEK 215
KK S + + DS++ S D + KK K+ KK N+ S+ S E TE
Sbjct: 86 KEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSE---TES 142
Query: 216 DSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKK 275
DSK K KK KD + + +K KK + +D ES + +E+ + KK K
Sbjct: 143 DSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEV-RAKKKKS 201
Query: 276 KPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTE 309
+ K KK+ KK + K KK A +
Sbjct: 202 SEEREKATEKTKKKKKHKKHSKKKKKKAASSSPD 235
Score = 51.6 bits (122), Expect = 1e-06
Identities = 53/184 (28%), Positives = 75/184 (40%), Gaps = 40/184 (21%)
Query: 110 KAAEIGKKGEDKTTQKDTTDSES--------ELKQGKKDSKKGKDIEKGKEEKL-DAKKD 160
K E K G ++ ++DS S + KQGK+ KK K E + + + D
Sbjct: 84 KKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESD 143
Query: 161 SKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKG 220
SK K +K KD + +D KG +KK K +D +S +ESE + E +KK
Sbjct: 144 SKDSLKKKKKSKDGTEKEKDIKGLSKK-RKMYSEDKPLSSESLSESEYIE---EVRAKKK 199
Query: 221 KKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSST 280
K ++ KA EK KK K K KK KKK +S+
Sbjct: 200 KSSEER----------EKATEK-----------------TKKKKKHKKHSKKKKKKAASS 232
Query: 281 DSDS 284
DS
Sbjct: 233 SPDS 236
Score = 47.8 bits (112), Expect = 1e-05
Identities = 43/154 (27%), Positives = 74/154 (48%), Gaps = 32/154 (20%)
Query: 213 TEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDES--KDAKKDAKEIKKG 270
T ++ K+ + KKG + E + EK +E+ KK+ K E ++ +K+ ++
Sbjct: 30 TWEEVKEQLEKKKKGSKALAEFE-----EKMNENWKKELEKHREKLLSGSESSSKKRQRK 84
Query: 271 KKDKKKP-------------SSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKK 317
KK+KKK SS+ SDS+D+ KK+ K+ K K + K +E ++++
Sbjct: 85 KKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKR--RKKKKNRSHKSSESSMSETES 142
Query: 318 DAKKNAKKDAKKDAKKNAKKD---EKKDAKKKGK 348
D+K + KK K KD ++KD K K
Sbjct: 143 DSKDSLKK-------KKKSKDGTEKEKDIKGLSK 169
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 77.4 bits (189), Expect = 2e-14
Identities = 61/205 (29%), Positives = 95/205 (46%), Gaps = 9/205 (4%)
Query: 133 ELKQGKKDSKKGKDIEKGKEEKLDA--KKDSKKGKKDAEKGKDSATESEDEKGGAKKDNK 190
E+K+ + KKG EEK++ KK+ +K ++ G +S+++ K KK+ K
Sbjct: 43 EVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRK---KKEKK 99
Query: 191 KDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKD 250
K + S+ S+ S ++D K+GK+ KK S ++ ++ + D K
Sbjct: 100 KSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSET--ESDSKDS 157
Query: 251 ANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEK 310
K +SKD + K+I KG K+K S D + ES+ AKK K E+
Sbjct: 158 LKKKKKSKDGTEKEKDI-KGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKK-KKSSEER 215
Query: 311 ESADSKKDAKKNAKKDAKKDAKKNA 335
E A K KK KK +KK KK A
Sbjct: 216 EKATEKTKKKKKHKKHSKKKKKKAA 240
Score = 73.6 bits (179), Expect = 3e-13
Identities = 58/214 (27%), Positives = 91/214 (42%), Gaps = 8/214 (3%)
Query: 100 KPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKK----GKDIEKGKEEKL 155
+P T E + E KKG + + +E+ K+ +K +K + K ++ K
Sbjct: 36 RPRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKK 95
Query: 156 DAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEK 215
KK S + + DS++ S D + KK K+ KK N+ S+ S E TE
Sbjct: 96 KEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSE---TES 152
Query: 216 DSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKK 275
DSK K KK KD + + +K KK + +D ES + +E+ + KK K
Sbjct: 153 DSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEV-RAKKKKS 211
Query: 276 KPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTE 309
+ K KK+ KK + K KK A +
Sbjct: 212 SEEREKATEKTKKKKKHKKHSKKKKKKAASSSPD 245
Score = 51.6 bits (122), Expect = 1e-06
Identities = 53/184 (28%), Positives = 75/184 (40%), Gaps = 40/184 (21%)
Query: 110 KAAEIGKKGEDKTTQKDTTDSES--------ELKQGKKDSKKGKDIEKGKEEKL-DAKKD 160
K E K G ++ ++DS S + KQGK+ KK K E + + + D
Sbjct: 94 KKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESD 153
Query: 161 SKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKG 220
SK K +K KD + +D KG +KK K +D +S +ESE + E +KK
Sbjct: 154 SKDSLKKKKKSKDGTEKEKDIKGLSKK-RKMYSEDKPLSSESLSESEYIE---EVRAKKK 209
Query: 221 KKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSST 280
K ++ KA EK KK K K KK KKK +S+
Sbjct: 210 KSSEER----------EKATEK-----------------TKKKKKHKKHSKKKKKKAASS 242
Query: 281 DSDS 284
DS
Sbjct: 243 SPDS 246
Score = 47.8 bits (112), Expect = 1e-05
Identities = 43/154 (27%), Positives = 74/154 (48%), Gaps = 32/154 (20%)
Query: 213 TEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDES--KDAKKDAKEIKKG 270
T ++ K+ + KKG + E + EK +E+ KK+ K E ++ +K+ ++
Sbjct: 40 TWEEVKEQLEKKKKGSKALAEFE-----EKMNENWKKELEKHREKLLSGSESSSKKRQRK 94
Query: 271 KKDKKKP-------------SSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKK 317
KK+KKK SS+ SDS+D+ KK+ K+ K K + K +E ++++
Sbjct: 95 KKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKR--RKKKKNRSHKSSESSMSETES 152
Query: 318 DAKKNAKKDAKKDAKKNAKKD---EKKDAKKKGK 348
D+K + KK K KD ++KD K K
Sbjct: 153 DSKDSLKK-------KKKSKDGTEKEKDIKGLSK 179
>gi|11225260 DNA topoisomerase I [Homo sapiens]
Length = 765
Score = 77.0 bits (188), Expect = 2e-14
Identities = 69/222 (31%), Positives = 96/222 (43%), Gaps = 28/222 (12%)
Query: 129 DSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKD 188
DS+ E DS K KD K +E + K+ KK +KD EK K S +E +D + K+
Sbjct: 9 DSQIEADFRLNDSHKHKDKHKDREHR---HKEHKK-EKDREKSKHSNSEHKDSEKKHKEK 64
Query: 189 NKKDKKD--SNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDED 246
K KD S K KD + + EK EK G KK K++ DE +D+
Sbjct: 65 EKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDD- 123
Query: 247 GKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKK 306
K+D K +K+ + +DD + KK T+D KK K+
Sbjct: 124 --------GYFVPPKEDIKPLKRPR------------DEDDADYKPKKIKTEDTKKEKKR 163
Query: 307 DTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
E+E D K KN KD K N KK KK+ ++K K
Sbjct: 164 KLEEEE-DGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKWK 204
Score = 57.8 bits (138), Expect = 1e-08
Identities = 49/163 (30%), Positives = 74/163 (45%), Gaps = 17/163 (10%)
Query: 116 KKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSA 175
K E K +K+ T + + KD K +D EK KEEK+ A D+K KK+ E G S
Sbjct: 55 KDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKI-KKEKENGFSSP 113
Query: 176 TESED--EKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIE 233
+ +D E G K+D K + +D K +D+KK KK
Sbjct: 114 PQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKR---------- 163
Query: 234 LQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKK 276
K +E++D KK NK + K + D K+ K K++++K
Sbjct: 164 ----KLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQK 202
Score = 51.6 bits (122), Expect = 1e-06
Identities = 50/184 (27%), Positives = 80/184 (43%), Gaps = 11/184 (5%)
Query: 117 KGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSAT 176
K +DK ++ E + ++ ++ SK K E+K K+ +K +EK KD
Sbjct: 23 KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHK 82
Query: 177 ESEDEKGGAKK----DNKKDKKDSNKGKDSATE--SEGEKGGTEKDSKKGKKDSKKGKDS 230
+ + EK +K + K KK+ G S + E E G K+ K K+ +D
Sbjct: 83 DRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDE 142
Query: 231 AIELQAVKADEKKDEDGKKD-ANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVK 289
+ K + K ED KK+ K +E +D K K+ K KDKK P + K +
Sbjct: 143 --DDADYKPKKIKTEDTKKEKKRKLEEEEDGK--LKKPKNKDKDKKVPEPDNKKKKPKKE 198
Query: 290 KESK 293
+E K
Sbjct: 199 EEQK 202
Score = 35.4 bits (80), Expect = 0.076
Identities = 22/94 (23%), Positives = 43/94 (45%), Gaps = 6/94 (6%)
Query: 254 GDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAK---KDTEK 310
GD + + + + K K D + + KE KK+ ++ K + KD+EK
Sbjct: 3 GDHLHNDSQIEADFRLNDSHKHKDKHKDREHRH---KEHKKEKDREKSKHSNSEHKDSEK 59
Query: 311 ESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAK 344
+ + +K K+ + KD K+ K+++K+ K
Sbjct: 60 KHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEK 93
Score = 33.1 bits (74), Expect = 0.38
Identities = 62/270 (22%), Positives = 103/270 (38%), Gaps = 27/270 (10%)
Query: 46 KRRSKPSQIRDNTVSIIDEEQLRGDRRQPLWMYRSLMRISERPSV--YLAARRQPLKPTR 103
K + K ++R + + I +E+ G P +I + P Y ++ +KP +
Sbjct: 86 KEKRKEEKVRASGDAKIKKEKENGFSSPP--------QIKDEPEDDGYFVPPKEDIKPLK 137
Query: 104 TVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKK 163
+ A KK + + T+K+ E + GK K KD K++K+ + KK
Sbjct: 138 RPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKD----KDKKVPEPDNKKK 193
Query: 164 GKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKD 223
K E+ K E E G K K +KG A E ++ K D
Sbjct: 194 KPKKEEEQKWKWWEEERYPEGIKW-----KFLEHKGPVFAPPYE-----PLPENVKFYYD 243
Query: 224 SK--KGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKD-AKEIKKGKKDKKKPSST 280
K K A E+ A E K+ + + KD +K+ E K + K T
Sbjct: 244 GKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFT 303
Query: 281 DSDSKDDVKKESKKDATKDAKKVAKKDTEK 310
+ E++K +K+ K K++ EK
Sbjct: 304 QMSQYFKAQTEARKQMSKEEKLKIKEENEK 333
Score = 30.4 bits (67), Expect = 2.5
Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 2/64 (3%)
Query: 147 IEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATES 206
I+ KE+ DA++D K K DA+ KD+ T+ E KK ++ ++ K + AT+
Sbjct: 651 IDAKKEQLADARRDLKSAKADAKVMKDAKTKKVVE--SKKKAVQRLEEQLMKLEVQATDR 708
Query: 207 EGEK 210
E K
Sbjct: 709 EENK 712
Score = 29.6 bits (65), Expect = 4.2
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 6/70 (8%)
Query: 278 SSTDSDSKDDVKKESKKDATKDAK------KVAKKDTEKESADSKKDAKKNAKKDAKKDA 331
S + +K D KKE DA +D K KV K K+ +SKK A + ++ K
Sbjct: 643 SMMNLQTKIDAKKEQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLE 702
Query: 332 KKNAKKDEKK 341
+ ++E K
Sbjct: 703 VQATDREENK 712
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 76.3 bits (186), Expect = 4e-14
Identities = 52/236 (22%), Positives = 91/236 (38%), Gaps = 15/236 (6%)
Query: 120 DKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESE 179
D++ D +SES+ S +G E K + KG +D + S T +
Sbjct: 469 DESNGNDDANSESD----NNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNS 524
Query: 180 DEKGGAKKDNK-KDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVK 238
D G N DK DS KGK +++S+ DS +S+ + +
Sbjct: 525 DSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSD 584
Query: 239 AD--EKKDEDGKKDANKGDESKDA----KKDAKEIKKGKKDKKKPS--STDSDSKDDVKK 290
+D + D D +N D S + D+ + K D K S+DSDSK D
Sbjct: 585 SDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSD 644
Query: 291 ESKKDAT--KDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAK 344
+ D++ D+ + +S+DS + ++ D+ + + D ++
Sbjct: 645 SNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSE 700
Score = 75.1 bits (183), Expect = 9e-14
Identities = 51/246 (20%), Positives = 94/246 (38%), Gaps = 18/246 (7%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
DSK AE D T+ + +DS G D+ K D KGK + D+ D
Sbjct: 506 DSKGAE--DDDSDSTSDTNNSDSNGNGNNGNDDNDKS-DSGKGKSDSSDSDSSDSSNSSD 562
Query: 168 AEKGKD-------SATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKG 220
+ D S+++S+ + + D DS+ DS+ S+ DS
Sbjct: 563 SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 622
Query: 221 KKDSKKGKDSAIELQAVKADEKKD--EDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPS 278
K DS K + + + +D K D + D++ +S D+ + S
Sbjct: 623 KSDSSKSESDSSD-----SDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDS 677
Query: 279 STDSDSKDDVKKESKKDATKDAKKVAKKD-TEKESADSKKDAKKNAKKDAKKDAKKNAKK 337
S+ SDS + D++ ++ D ++ +S+DS + N+ ++ ++
Sbjct: 678 SSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS 737
Query: 338 DEKKDA 343
D+
Sbjct: 738 SNSSDS 743
Score = 73.9 bits (180), Expect = 2e-13
Identities = 45/238 (18%), Positives = 86/238 (36%), Gaps = 6/238 (2%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
DS +++ + ++ D++DS +S D + DS K D
Sbjct: 568 DSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSS--DSSDSSDSKSD 625
Query: 168 AEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDS--KKGKKDSK 225
+ K + +++S D K + N D D++ DS+ S DS DS
Sbjct: 626 SSKSESDSSDS-DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSS 684
Query: 226 KGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSK 285
DS+ + + E D D++ D S + ++ + SS SDS
Sbjct: 685 NSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS 744
Query: 286 DDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDA 343
D + D++ D+ + +S+DS + + D+ + + D +
Sbjct: 745 DSSDSSNSSDSS-DSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSS 801
Score = 72.4 bits (176), Expect = 6e-13
Identities = 46/239 (19%), Positives = 85/239 (35%), Gaps = 7/239 (2%)
Query: 105 VEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKG 164
+E + +E G K T D+ + S +G D E + +S+
Sbjct: 423 IEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESD 482
Query: 165 KKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDS 224
+ +G S E + G D+K + D + S+ G + K DS
Sbjct: 483 NNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDS 542
Query: 225 KKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDS 284
KGK + + + + D D++ D + + D+ D S+DSDS
Sbjct: 543 GKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDS-------SDSDSSDSSDSDS 595
Query: 285 KDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDA 343
D D++ + D+ +DS K ++ D+K D+ + D ++
Sbjct: 596 SDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNS 654
Score = 72.0 bits (175), Expect = 7e-13
Identities = 49/247 (19%), Positives = 95/247 (38%), Gaps = 8/247 (3%)
Query: 101 PTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKD 160
P + E +K + + D+ D + + QG D D G ++ +
Sbjct: 426 PGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQG--DDPNSSDESNGNDDANSESDN 483
Query: 161 SKKGKKDAEKGKDSATESED--EKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSK 218
+ + DA D + ++ + + GA+ D+ D+N + + G + DS
Sbjct: 484 NSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSG 543
Query: 219 KGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPS 278
KGK DS DS+ + + + D D D+N +S + D+ + S
Sbjct: 544 KGKSDS-SDSDSSDSSNSSDSSDSSDSD-SSDSNSSSDSDSSDSDSSDSSDSDSSDSSNS 601
Query: 279 STDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDA--KKDAKKNAK 336
S SDS D D++ +K +++ +DSK D+ + D+ D+ ++
Sbjct: 602 SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN 661
Query: 337 KDEKKDA 343
D+
Sbjct: 662 SSNSSDS 668
Score = 70.1 bits (170), Expect = 3e-12
Identities = 42/238 (17%), Positives = 90/238 (37%), Gaps = 10/238 (4%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
DS + D + +++DS DS D + + D+ S D
Sbjct: 541 DSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDS---SDSDSSD 597
Query: 168 AEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKG 227
+ DS+ S+ D+ K DS+K + +++S+ + ++ +S DS
Sbjct: 598 SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNS----SDSSDN 653
Query: 228 KDSAIELQAVKADEKKDEDGKKDANKGDESKDA--KKDAKEIKKGKKDKKKPSSTDSDSK 285
DS+ + + + D D++ +S ++ D+ + + S+DSDS
Sbjct: 654 SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS 713
Query: 286 DDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDA 343
D + + D+ + S+DS D+ ++ D+ ++ + D+
Sbjct: 714 DSSDSSNSNSSDSDSSNSSDSSDSSNSSDS-SDSSDSSNSSDSSDSSDSSNSSDSSDS 770
Score = 69.3 bits (168), Expect = 5e-12
Identities = 48/244 (19%), Positives = 82/244 (33%), Gaps = 7/244 (2%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDS-ESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKK 166
DS + D + D++DS +S DS + D +
Sbjct: 1047 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSS 1106
Query: 167 DAEKGKDSATESEDEKGGAKKDNK--KDKKDSNKGKDSATESEGEKGGTEKDS--KKGKK 222
D+ DS+ S+ D+ D DS+ DS+ SE DS
Sbjct: 1107 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSS 1166
Query: 223 DSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDS 282
DS DS+ + + + D D++ +S D+ + SS S
Sbjct: 1167 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1226
Query: 283 DSKDDVKKESKKDA--TKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEK 340
DS D + D+ + D+ + +S+DS D+ + +K N D
Sbjct: 1227 DSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSD 1286
Query: 341 KDAK 344
D++
Sbjct: 1287 SDSE 1290
Score = 68.2 bits (165), Expect = 1e-11
Identities = 42/238 (17%), Positives = 81/238 (34%), Gaps = 8/238 (3%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
DS + D + D++DS S +S D + + + D
Sbjct: 949 DSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSD 1008
Query: 168 AEKGKDSATESE-----DEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKK 222
+ DS+ S+ D + + D DS+ DS+ S+ DS
Sbjct: 1009 SSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS-SDSS 1067
Query: 223 DSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDA--KKDAKEIKKGKKDKKKPSST 280
DS DS+ + ++ + D D++ +S D+ D+ + S+
Sbjct: 1068 DSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1127
Query: 281 DSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKD 338
DS D S + D+ + + +S+DS + + D+ + + D
Sbjct: 1128 DSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1185
Score = 67.8 bits (164), Expect = 1e-11
Identities = 48/243 (19%), Positives = 83/243 (34%), Gaps = 8/243 (3%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDS-ESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKK 166
DS + D + D++DS +S DS D + +
Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1073
Query: 167 DAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDS--KKGKKDS 224
D+ DS+ ES D + + D DS+ DS+ S+ +S DS
Sbjct: 1074 DSSDSSDSS-ESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1132
Query: 225 KKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDS 284
DS+ + + E D D++ +S D+ + SS SDS
Sbjct: 1133 SDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1192
Query: 285 KD--DVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDA--KKDAKKNAKKDEK 340
D D S + D+ + +S+DS + N D+ D+ ++ +
Sbjct: 1193 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDS 1252
Query: 341 KDA 343
D+
Sbjct: 1253 SDS 1255
Score = 67.4 bits (163), Expect = 2e-11
Identities = 44/239 (18%), Positives = 83/239 (34%), Gaps = 9/239 (3%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDS-ESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKK 166
DS + D + D++DS +S DS D + + +
Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 1034
Query: 167 DAEKGKDSA-----TESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKG- 220
D+ DS+ ++S D + + D DS+ DS+ S+ + DS
Sbjct: 1035 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSS 1094
Query: 221 -KKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSS 279
DS DS+ + + + D D++ +S D+ + + SS
Sbjct: 1095 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154
Query: 280 TDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKD 338
SDS D D++ D+ + +S+DS + + D+ + + D
Sbjct: 1155 DSSDSSDSSDSSDSSDSS-DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1212
Score = 67.0 bits (162), Expect = 2e-11
Identities = 43/243 (17%), Positives = 77/243 (31%), Gaps = 9/243 (3%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
DS + D + D+ S+S DS D + ++ D
Sbjct: 884 DSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSD 943
Query: 168 AEKGKDSATESEDEKGG-------AKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKG 220
+ DS+ S+ + N D DS+ DS+ S+ DS
Sbjct: 944 SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS-SN 1002
Query: 221 KKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSST 280
DS DS+ + + D D++ +S D+ + SS
Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1062
Query: 281 DSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEK 340
SDS D D++ D+ + + S+DS + + D+ + + D
Sbjct: 1063 SSDSSDSSDSSDSSDSS-DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1121
Query: 341 KDA 343
+
Sbjct: 1122 NSS 1124
Score = 67.0 bits (162), Expect = 2e-11
Identities = 44/240 (18%), Positives = 85/240 (35%), Gaps = 7/240 (2%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDS-ESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKK 166
DS + D + D++DS +S DS D + + +
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSS 1100
Query: 167 DAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKK 226
D+ DS+ +S D + N D DS+ DS+ S +S DS
Sbjct: 1101 DSSDSSDSS-DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESS----DSSD 1155
Query: 227 GKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKD 286
DS+ + + + D +++ +S D+ + SS SDS D
Sbjct: 1156 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1215
Query: 287 DVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
D++ D+ + +S+DS + + D+ + + +++ D++ K
Sbjct: 1216 SSDSSDSSDSS-DSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274
Score = 66.2 bits (160), Expect = 4e-11
Identities = 42/245 (17%), Positives = 79/245 (32%), Gaps = 12/245 (4%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
DS + + + D++DS+S DS + D+ S
Sbjct: 688 DSSDSSDSSNSSESSDSSDSSDSDSS---DSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS 744
Query: 168 AEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDS--KKGKKDSK 225
++++S D + + D DS+ DS+ S+ DS DS
Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804
Query: 226 KGKDSAIELQAVKADEKKDEDGKKDANKGDESKDA-------KKDAKEIKKGKKDKKKPS 278
DS+ + +D D ++ D S + D + + S
Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864
Query: 279 STDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKD 338
S SDS D D++ + D+ S S D+ ++ D+ ++
Sbjct: 865 SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSS 924
Query: 339 EKKDA 343
E ++
Sbjct: 925 ESSNS 929
Score = 66.2 bits (160), Expect = 4e-11
Identities = 43/240 (17%), Positives = 84/240 (35%), Gaps = 9/240 (3%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
+S + D + D++DS DS D + DS
Sbjct: 925 ESSNSSDNSNSSDSSNSSDSSDSSDS--SNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNS 982
Query: 168 AEKGKDS----ATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKD 223
++ S +++S D + + D DS+ DS+ S+ DS D
Sbjct: 983 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS-SDSSD 1041
Query: 224 SKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSD 283
S DS+ + + + D D++ +S D+ ++ SS SD
Sbjct: 1042 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101
Query: 284 SKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDA 343
S D D++ D+ + +S+DS D+ ++ D+ +++ + D+
Sbjct: 1102 SSDSSDSSDSSDSS-DSSDSSNSSDSSDSSDS-SDSSDSSNSSDSSDSSESSDSSDSSDS 1159
Score = 65.9 bits (159), Expect = 5e-11
Identities = 44/234 (18%), Positives = 80/234 (34%), Gaps = 5/234 (2%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSE-SELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKK 166
DS + D + D++DS S DS D + +
Sbjct: 993 DSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052
Query: 167 DAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDS--KKGKKDS 224
D+ DS+ +S D + + D DS++ DS+ S DS DS
Sbjct: 1053 DSSNSSDSS-DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDS 1111
Query: 225 KKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDS 284
DS+ + + + D D++ +S D+ + + SS SDS
Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDS 1171
Query: 285 KDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKD 338
D + D++ D+ + +S+DS + + D+ + + D
Sbjct: 1172 SDSSDSSNSSDSS-DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1224
Score = 65.1 bits (157), Expect = 9e-11
Identities = 42/225 (18%), Positives = 82/225 (36%), Gaps = 5/225 (2%)
Query: 120 DKTTQKDTTDS-ESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATES 178
D + D++DS +S DS D + + D+ DS+ +S
Sbjct: 978 DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSS-DS 1036
Query: 179 EDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVK 238
D + + D DS+ DS+ S+ DS DS + DS+ +
Sbjct: 1037 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS-SDSSDSSESSDSSDSSNSSD 1095
Query: 239 ADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATK 298
+ + D D++ +S D+ D+ S+DS + D S+ +
Sbjct: 1096 SSDSSDSSDSSDSSDSSDSSDS-SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154
Query: 299 DAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDA 343
D+ + +S+DS D+ ++ D+ ++ + D+
Sbjct: 1155 DSSDSSDSSDSSDSSDS-SDSSDSSNSSDSSDSSDSSDSSDSSDS 1198
Score = 64.7 bits (156), Expect = 1e-10
Identities = 45/256 (17%), Positives = 95/256 (37%), Gaps = 32/256 (12%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSE----SELKQGKKDSKKGKDIEKGKEEKLDAKKDSKK 163
D +++ +D ++ D S S KD+ G D + +++ D+ D+
Sbjct: 464 DPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNN 523
Query: 164 G--------------KKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGE 209
K D+ KGK +++S+ D+ + +S+++S+
Sbjct: 524 SDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSS 583
Query: 210 KGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKK 269
+ S DS DS+ D D++ +S D+K D+ + +
Sbjct: 584 DSDSSDSSDSDSSDSSNSSDSS------------DSSDSSDSSDSSDSSDSKSDSSKSES 631
Query: 270 GKKDK-KKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKES-ADSKKDAKKNAKKDA 327
D K S+DS+S D D++ + D+ S + S D+ ++
Sbjct: 632 DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691
Query: 328 KKDAKKNAKKDEKKDA 343
D+ +++ + D+
Sbjct: 692 SSDSSNSSESSDSSDS 707
Score = 64.7 bits (156), Expect = 1e-10
Identities = 39/227 (17%), Positives = 80/227 (35%), Gaps = 5/227 (2%)
Query: 117 KGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSAT 176
K + ++ D++DS+S+ +S D + + + D+ DS++
Sbjct: 623 KSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDS---SNSSNSSDSSDSSDSSDSSS 679
Query: 177 ESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQA 236
S D + + D +S++ DS+ S+ + + S DS S +
Sbjct: 680 -SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS 738
Query: 237 VKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDA 296
+D D ++ D S D+ + SS SDS D D+
Sbjct: 739 NSSDSSDSSDSSNSSDSSD-SSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797
Query: 297 TKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDA 343
+ + D+ S S D+ ++ D+ ++ + D+
Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS 844
Score = 64.7 bits (156), Expect = 1e-10
Identities = 42/236 (17%), Positives = 81/236 (34%), Gaps = 11/236 (4%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
DS + D + D++DS S DS D + ++ D
Sbjct: 655 DSSDSSNSSNSSDSSDSSDSSDSSSS-----SDSSNSSDSSDSSDSSNSSESSDSSDSSD 709
Query: 168 AEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKG 227
++ DS+ S + N D DS+ DS+ S+ DS DS
Sbjct: 710 SDSS-DSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS----SDSSNS 764
Query: 228 KDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDD 287
DS+ + + + + D++ +S D+ ++ + S+DSDS +
Sbjct: 765 SDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS-SNSSDSSNSSDSSDSSDSSDSDSSNS 823
Query: 288 VKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDA 343
+ D++ + D+ S S D+ + D+ ++ D+
Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDS 879
Score = 64.7 bits (156), Expect = 1e-10
Identities = 46/246 (18%), Positives = 81/246 (32%), Gaps = 16/246 (6%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDS----ESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKK 163
DS + D + D++DS ES DS D + DS
Sbjct: 860 DSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSN 919
Query: 164 GKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDS----KK 219
+E ++ S D + N D DS+ +S+ S DS
Sbjct: 920 SSDSSE-----SSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS 974
Query: 220 GKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSS 279
DS DS+ + + + D D++ +S D+ + SS
Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 1034
Query: 280 TDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADS--KKDAKKNAKKDAKKDAKKNAKK 337
SDS D D++ D+ + +S+DS D+ ++ D+ ++
Sbjct: 1035 DSSDSSDSSDSSDSSDSS-DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNS 1093
Query: 338 DEKKDA 343
+ D+
Sbjct: 1094 SDSSDS 1099
Score = 64.7 bits (156), Expect = 1e-10
Identities = 42/211 (19%), Positives = 80/211 (37%), Gaps = 5/211 (2%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDS-ESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKK 166
DS + D + D++DS +S DS D + + +
Sbjct: 1086 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS 1145
Query: 167 DAEKGKDSA--TESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDS 224
D+ + DS+ ++S D + + D DS+ DS+ S+ DS DS
Sbjct: 1146 DSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS-SDSSDS 1204
Query: 225 KKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDS 284
DS+ + + + D D+N+ +S D+ D+ + S+DS S
Sbjct: 1205 SDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDS-SDSSDSSNSSDSSDSSDSSDSTS 1263
Query: 285 KDDVKKESKKDATKDAKKVAKKDTEKESADS 315
+ + +S+ + + D++ E +DS
Sbjct: 1264 DSNDESDSQSKSGNGNNNGSDSDSDSEGSDS 1294
Score = 63.5 bits (153), Expect = 3e-10
Identities = 46/239 (19%), Positives = 80/239 (33%), Gaps = 11/239 (4%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDS-ESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKK 166
DS + D + D++DS +S DS D +
Sbjct: 736 DSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSS 795
Query: 167 DAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKK 226
D+ DS+ S+ D+ DS+ DS+ S+ DS DS
Sbjct: 796 DSSNSSDSSNSSDSSDSSDSSDS-----DSSNSSDSSNSSDSSDSSNSSDSSDSS-DSSD 849
Query: 227 GKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKD 286
G DS ++ ++ D +N D S + D+ E +S+DSDS D
Sbjct: 850 GSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS--DSNESSNSSDSSDSSNSSDSDSSD 907
Query: 287 DVKKESKKDA--TKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDA 343
D+ + D+ + + S+DS + + D+ + + D +
Sbjct: 908 SSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966
Score = 63.5 bits (153), Expect = 3e-10
Identities = 43/247 (17%), Positives = 85/247 (34%), Gaps = 10/247 (4%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSE-SELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKK 166
DS + D + D+++S S DS D + + +
Sbjct: 904 DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSS 963
Query: 167 DAEKGKDS-ATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDS-----KKG 220
++ DS +++S D + + D DS+ DS+ S+ DS
Sbjct: 964 NSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSN 1023
Query: 221 KKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSST 280
DS DS+ + + + D D++ +S D+ + SS
Sbjct: 1024 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSE 1083
Query: 281 DSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDA--KKDAKKNAKKD 338
SDS D D++ D+ + +S+DS + + D+ D+ ++
Sbjct: 1084 SSDSSDSSNSSDSSDSS-DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 1142
Query: 339 EKKDAKK 345
+ D+ +
Sbjct: 1143 DSSDSSE 1149
Score = 63.2 bits (152), Expect = 3e-10
Identities = 46/245 (18%), Positives = 81/245 (33%), Gaps = 15/245 (6%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
DS + D + D++DS S+ K DS K + + K D+ + D
Sbjct: 594 DSSDSSNSSDSSDSSDSSDSSDS-SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSD 652
Query: 168 AEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGK------ 221
DS+ S + + D DS+ DS+ S+ +S +
Sbjct: 653 NSDSSDSSNSSNS----SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSS 708
Query: 222 -KDSKKGKDSAIELQAVKADEKKDEDGKKDANKGD--ESKDAKKDAKEIKKGKKDKKKPS 278
DS DS+ + +D D +N D +S D+ + S
Sbjct: 709 DSDSSDSSDSS-NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDS 767
Query: 279 STDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKD 338
S SDS D + D+ + D+ S S ++ + D+ ++
Sbjct: 768 SDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSS 827
Query: 339 EKKDA 343
D+
Sbjct: 828 NSSDS 832
Score = 63.2 bits (152), Expect = 3e-10
Identities = 40/239 (16%), Positives = 78/239 (32%), Gaps = 10/239 (4%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
DS + D + D++DS+S +S D + DS G
Sbjct: 796 DSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSS--DSSDSSDGSDS 853
Query: 168 AEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKG-KKDSKK 226
+ ++ S D + N D DS+ +S+ S+ DS +S
Sbjct: 854 DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913
Query: 227 GKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEI-------KKGKKDKKKPSS 279
DS+ + ++ D D++ +S D+ + D +S
Sbjct: 914 SSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973
Query: 280 TDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKD 338
+DS + S + D+ + +S+DS + + D+ + + D
Sbjct: 974 SDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSD 1032
Score = 63.2 bits (152), Expect = 3e-10
Identities = 40/232 (17%), Positives = 77/232 (33%), Gaps = 6/232 (2%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
DS +++ + + + SES +S + + + D
Sbjct: 902 DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961
Query: 168 AEKGKDSA-TESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKK 226
+ DS+ + S D + + D DS+ DS+ S DS DS
Sbjct: 962 SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS----SDSSN 1017
Query: 227 GKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKD 286
DS+ + + + D D++ +S D+ + SS SDS D
Sbjct: 1018 SSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1077
Query: 287 DVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKD 338
D++ D+ + +S+DS + + D+ + + D
Sbjct: 1078 SSDSSESSDSS-DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1128
Score = 63.2 bits (152), Expect = 3e-10
Identities = 43/238 (18%), Positives = 81/238 (34%), Gaps = 11/238 (4%)
Query: 108 DSKAAEIGKKGEDKTTQKD---TTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKG 164
DS + D + D ++DS + +S D + +
Sbjct: 937 DSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSD 996
Query: 165 KKDAEKGKDS--ATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKK 222
D+ DS +++S D + N D +S+ DS+ S+ DS
Sbjct: 997 SSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDS----S 1052
Query: 223 DSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDS 282
DS DS+ + + + D D+++ +S D+ + SS S
Sbjct: 1053 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1112
Query: 283 DSKD--DVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKD 338
DS D D S + D+ + +S+DS + + + D+ + + D
Sbjct: 1113 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSD 1170
Score = 63.2 bits (152), Expect = 3e-10
Identities = 44/238 (18%), Positives = 83/238 (34%), Gaps = 8/238 (3%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSE-SELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKK 166
DS + D + D++DS S DS D + + +
Sbjct: 1068 DSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1127
Query: 167 DAEKGKDSA--TESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDS 224
D+ DS+ + S D ++ + D DS+ DS+ S+ ++ DS
Sbjct: 1128 DSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSD----SSDSSDSSNSSDS 1183
Query: 225 KKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDS 284
DS+ + + + D D++ +S D+ + ++ SS SDS
Sbjct: 1184 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDS 1243
Query: 285 KDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKD 342
D D++ + + + E +S SK N D+ D++ + D
Sbjct: 1244 SDSSNSSDSSDSSDSSDSTSDSNDESDS-QSKSGNGNNNGSDSDSDSEGSDSNHSTSD 1300
Score = 62.4 bits (150), Expect = 6e-10
Identities = 41/238 (17%), Positives = 76/238 (31%), Gaps = 10/238 (4%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
DS + D + D +DS+S + +S D + +
Sbjct: 831 DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSN 890
Query: 168 AEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKG 227
+ DS+ S+ + + N D DS+ DS+ S DS DS
Sbjct: 891 SSDSSDSSNSSDSDSSDSS--NSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS-DSSDS 947
Query: 228 KDSAIELQAVKADEKKDEDGKKDANKGDESKDA-------KKDAKEIKKGKKDKKKPSST 280
DS+ + + + + D+N D S + D+ + S+
Sbjct: 948 SDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS 1007
Query: 281 DSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKD 338
DS D S + D+ + +S+DS + + D+ + + D
Sbjct: 1008 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1065
Score = 62.4 bits (150), Expect = 6e-10
Identities = 41/231 (17%), Positives = 74/231 (32%), Gaps = 3/231 (1%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
DS + + + S+S DS D + + D
Sbjct: 961 DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020
Query: 168 AEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKG 227
+ DS + S D + + D DS+ DS+ S+ DS DS
Sbjct: 1021 SSNSSDS-SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS-SDSSDSSDS 1078
Query: 228 KDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDD 287
DS+ + + D D++ +S D+ + SS SDS D
Sbjct: 1079 SDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1138
Query: 288 VKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKD 338
D+++ + D+ +S+DS + + D+ + + D
Sbjct: 1139 SNSSDSSDSSESSDSSDSSDS-SDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1188
Score = 62.4 bits (150), Expect = 6e-10
Identities = 44/241 (18%), Positives = 84/241 (34%), Gaps = 7/241 (2%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSE-SELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKK 166
DS + D + +++DS S DS D + +
Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058
Query: 167 DAEKGKDS--ATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDS 224
D+ DS +++S D + D DS+ DS+ S+ DS DS
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDS-SDSSDS 1117
Query: 225 KKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDA--KKDAKEIKKGKKDKKKPSSTDS 282
+S+ + + + D D++ ES D+ D+ + S+DS
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177
Query: 283 DSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKD 342
+ D S + D+ + +S+DS D+ ++ D+ ++ +E D
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS-SDSSDSSDSSDSSDSSDSSDSNESSD 1236
Query: 343 A 343
+
Sbjct: 1237 S 1237
Score = 61.2 bits (147), Expect = 1e-09
Identities = 41/237 (17%), Positives = 82/237 (34%), Gaps = 6/237 (2%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
DS + D + D++DS DS D + + +
Sbjct: 748 DSSNSSDSSDSSDSSNSSDSSDSSDS--SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805
Query: 168 AEKGKDSATESE-DEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKK 226
+ DS+ S+ D + N D DS+ DS ++S G++ DS + DS
Sbjct: 806 SSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS-SDSSDSSDGSDSDS-SNRSDSSN 863
Query: 227 GKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKD 286
DS+ + + + D +++ +S D+ ++ + SS S+S D
Sbjct: 864 SSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDS-SNSSDSDSSDSSNSSDSSDSSNSSD 922
Query: 287 DVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDA 343
+ + D + + D+ S S N+ + ++ + D+
Sbjct: 923 SSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDS 979
Score = 60.5 bits (145), Expect = 2e-09
Identities = 38/240 (15%), Positives = 80/240 (33%), Gaps = 11/240 (4%)
Query: 109 SKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDA 168
S +++ ++ +++DS+S DS D + + ++
Sbjct: 705 SDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNS 764
Query: 169 EKGKDSATESEDEKGGAKKD-----NKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKD 223
DS+ S+ D N D DS+ DS+ S+ DS D
Sbjct: 765 SDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDS-----D 819
Query: 224 SKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSD 283
S DS+ + + D D++ G +S + + D SS SD
Sbjct: 820 SSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD-SSDSSNSSD 878
Query: 284 SKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDA 343
S D +++ + D++ + + D+ ++ ++ ++ D+
Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938
Score = 59.7 bits (143), Expect = 4e-09
Identities = 42/242 (17%), Positives = 85/242 (35%), Gaps = 13/242 (5%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
DS + D + D+ DS + DS D D+ S D
Sbjct: 766 DSSDSSDSSDSSDSSNSSDSNDSSNS--SDSSDSSNSSDSSNSS----DSSDSSDSSDSD 819
Query: 168 AEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKG-KKDSKK 226
+ DS+ S D + + D DS+ G DS + + + + S +S
Sbjct: 820 SSNSSDSSNSS-DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSD 878
Query: 227 GKDSAIELQAVKADEKKDEDGKKDANKGDESKDA----KKDAKEIKKGKKDKKKPSSTDS 282
DS+ ++ + + D D++ D S + ++ + + +S+DS
Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938
Query: 283 DSKDDVKKESKKDATKDAKKVAKKDTEKESADS-KKDAKKNAKKDAKKDAKKNAKKDEKK 341
+ D S + D+ + +S+DS D+ ++ D+ ++ +
Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS 998
Query: 342 DA 343
D+
Sbjct: 999 DS 1000
Score = 59.3 bits (142), Expect = 5e-09
Identities = 39/234 (16%), Positives = 78/234 (33%), Gaps = 5/234 (2%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
DS + + + D++DS + + D + DS
Sbjct: 673 DSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSS 732
Query: 168 AEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKG 227
++++S D + + D DS+ DS ++S ++ + DS
Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDS-SDSSDSSDSSDSSNSSDSNDSSNS 791
Query: 228 KDSAIELQAVKADEKKDEDGKKDANKGD--ESKDAKKDAKEIKKGKKDKKKPSSTDSDSK 285
DS+ + + D D++ D S D+ + SS SD
Sbjct: 792 SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS 851
Query: 286 D-DVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKD 338
D D S + D+ + +S+DS D+ +++ D+ ++ D
Sbjct: 852 DSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS-SDSNESSNSSDSSDSSNSSDSD 904
Score = 49.3 bits (116), Expect = 5e-06
Identities = 64/282 (22%), Positives = 111/282 (39%), Gaps = 47/282 (16%)
Query: 109 SKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKK----GKDIEKGKEEKLDAK------ 158
SK AE+G G+ +T + E ++ D+ K G D GKEE + A
Sbjct: 83 SKWAEVG--GKSFSTYSTLANEEGNIEGWNGDTGKAETYGHDGIHGKEENITANGIQGQV 140
Query: 159 -------------------KDSKKGKK-DAEKGKDSATESEDEKGGAKKDNKKDKKD--- 195
K+++ G DA +D A ED A +N D +D
Sbjct: 141 SIIDNAGATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEII 200
Query: 196 --SNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVK-----ADEKKDE--- 245
S + + + +E + +K+ + G+D+ ++ ADE +DE
Sbjct: 201 ENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSG 260
Query: 246 -DGKKDANKGDESKDAKKDAKEIKKGKKDKKKPS-STDSDSKDDVKKESKKDATKDAKKV 303
D ++A G +S + K + GK+D S +SDSK+ E K+D +
Sbjct: 261 DDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGD 320
Query: 304 AKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKK 345
+E+ SA +D +D +K + +K+ E + K+
Sbjct: 321 KTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKE 362
Score = 49.3 bits (116), Expect = 5e-06
Identities = 69/300 (23%), Positives = 113/300 (37%), Gaps = 67/300 (22%)
Query: 107 VDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDS---KKGKD-IEKGKEEKLDA----K 158
+D+ G D+ + + D E E KDS KG++ + GKE+ D+
Sbjct: 239 LDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQN 298
Query: 159 KDSK-----KGKKDA--EKGKDSATESEDEKGGAKKDN-------------KKDKKDSN- 197
DSK +GK+D E D ++SE+ G +DN ++ K+ N
Sbjct: 299 SDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENR 358
Query: 198 -----------KGKDSATESEGEKGGTEKDSK------KGKKDSKKGKDSAI-------- 232
K +D E +G G +K +GK+D KG+ I
Sbjct: 359 ITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKED--KGQHGMILGKGNVKT 416
Query: 233 --ELQAVKADEKKDEDGKK--DANKGDESKDAKKDAKEIKKGKKDKKKPSSTD-SDSKDD 287
E+ ++ +K E G K +N G +S D+ + P+S+D S+ DD
Sbjct: 417 QGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDD 476
Query: 288 VKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKG 347
ES D ++ D S +SK + + K A+ D + D+ G
Sbjct: 477 ANSES------DNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNG 530
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 75.5 bits (184), Expect = 7e-14
Identities = 46/221 (20%), Positives = 112/221 (50%), Gaps = 9/221 (4%)
Query: 129 DSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKD 188
D++ + +Q ++D + K KE D K+D ++ +K+ E ++ E + E ++D
Sbjct: 71 DADGDDRQRERDRVREKT---EKERDRDRKRDRERRRKEKETNRNRDREKQTE---IERD 124
Query: 189 NKKDK-KDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDG 247
+++K K + +D E E ++ ++ ++ +KD +++ E + + EK+ E
Sbjct: 125 REREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKE-- 182
Query: 248 KKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKD 307
++ D +D +K+ + ++D+++ + T+ + D + E + D ++ ++ +
Sbjct: 183 RETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRG 242
Query: 308 TEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
E++ +K+ +K +K +K +K KK+EK+ KK K
Sbjct: 243 KERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283
Score = 74.3 bits (181), Expect = 1e-13
Identities = 48/211 (22%), Positives = 108/211 (51%), Gaps = 14/211 (6%)
Query: 110 KAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAE 169
+ E +K D+ ++D E ++ +K++ + +D EK E + D +++ +KG+ E
Sbjct: 83 RVREKTEKERDRDRKRDR-----ERRRKEKETNRNRDREKQTEIERDREREKQKGR---E 134
Query: 170 KGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKD 229
+ +D E E ++ K+ ++ +KD + +++ TE E ++ ++ ++ ++D + +D
Sbjct: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRD 194
Query: 230 SAIELQAVKADEKKDEDGKKDANKG---DESKDAKKDAKEIKKGKKDKKKPSSTDSDSKD 286
+ E + + D ++D K + D + + D + ++ +D+ K + D K+
Sbjct: 195 TEKERER-QTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKE 253
Query: 287 DVKKESKKDATKDAKKVAKKDTEKESADSKK 317
+ KKE KK+ K+ K+ KK EK D K+
Sbjct: 254 ERKKERKKERKKERKE--KKKEEKRREDKKR 282
Score = 68.2 bits (165), Expect = 1e-11
Identities = 45/220 (20%), Positives = 114/220 (51%), Gaps = 15/220 (6%)
Query: 118 GEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKG---KKDAEKGKDS 174
G+D+ ++D ++E K+ +D K+ ++ + KE++ + +D +K ++D E+ K
Sbjct: 74 GDDRQRERDRVREKTE-KERDRDRKRDRE-RRRKEKETNRNRDREKQTEIERDREREKQK 131
Query: 175 ATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIEL 234
E E ++G ++ ++D ++ K+ ++E ++ G + + ++D ++ K E
Sbjct: 132 GRERERDRG------RERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERET 185
Query: 235 QAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDS--DSKDDVKKES 292
+ + D ++D + +++ + D +D ++ + ++ + D++ TD + + D +
Sbjct: 186 ERDR-DRQRDTEKERE-RQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGK 243
Query: 293 KKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAK 332
++D +D K+ KK+ +KE +K+ KK K+ K K
Sbjct: 244 ERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283
Score = 35.0 bits (79), Expect = 0.100
Identities = 19/93 (20%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Query: 254 GDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESA 313
G KDA D ++ ++ + +K D D K D ++ +K+ + + +K TE E
Sbjct: 66 GQAHKDADGDDRQRERDRVREKTEKERDRDRKRD-RERRRKEKETNRNRDREKQTEIE-R 123
Query: 314 DSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
D +++ +K +++ + ++ +D +K+ +++
Sbjct: 124 DREREKQKGRERERDRGRERERDRDREKERERQ 156
>gi|112380630 leiomodin 1 (smooth muscle) [Homo sapiens]
Length = 600
Score = 74.7 bits (182), Expect = 1e-13
Identities = 78/274 (28%), Positives = 124/274 (45%), Gaps = 31/274 (11%)
Query: 90 VYLAARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEK 149
V L R Q K + V +K K Q++ + ES+ + K D+K G++ +
Sbjct: 47 VGLRQRNQTEKQSTGVYNREAMLNFCEKETKKLMQREMSMDESKQVETKTDAKNGEERGR 106
Query: 150 GKEEK-LDAKKDSKKGKKDAEKG-KDSATESEDEKGGAKKDNKKDKK---DSNKGKDSAT 204
+K L ++DS GK+ G K S + DE GG + K++K +KG+ A
Sbjct: 107 DASKKALGPRRDSDLGKEPKRGGLKKSFSRDRDEAGGKSGEKPKEEKIIRGIDKGRVRAA 166
Query: 205 ESEGEKG----GTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESK-- 258
+ E G G E+ K++ KKG D L K +KK E+ K+ A K D+ K
Sbjct: 167 VDKKEAGKDGRGEERAVATKKEEEKKGSDRNTGLSRDK--DKKREEMKEVAKKEDDEKVK 224
Query: 259 DAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKK--------DATKDAKKVAKKDT-- 308
+++ K+G+K K+ +TD +KKE +K D KD +KV K +
Sbjct: 225 GERRNTDTRKEGEKMKRAGGNTD------MKKEDEKVKRGTGNTDTKKDDEKVKKNEPLH 278
Query: 309 EKESADSK--KDAKKNAKKDAKKDAKKNAKKDEK 340
EKE+ D K +K K ++ AK +E+
Sbjct: 279 EKEAKDDSKTKTPEKQTPSGPTKPSEGPAKVEEE 312
Score = 46.2 bits (108), Expect = 4e-05
Identities = 35/149 (23%), Positives = 63/149 (42%), Gaps = 7/149 (4%)
Query: 200 KDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKD 259
K++ + E E + K D+K G++ + ++D D K+ +G K
Sbjct: 74 KETKKLMQREMSMDESKQVETKTDAKNGEERGRDASKKALGPRRDSDLGKEPKRGGLKKS 133
Query: 260 AKKDAKEI--KKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKK 317
+D E K G+K K++ D KK+A KD + E+ A K+
Sbjct: 134 FSRDRDEAGGKSGEKPKEEKIIRGIDKGRVRAAVDKKEAGKDG-----RGEERAVATKKE 188
Query: 318 DAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
+ KK + ++ K+ K++E K+ KK
Sbjct: 189 EEKKGSDRNTGLSRDKDKKREEMKEVAKK 217
Score = 40.4 bits (93), Expect = 0.002
Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 10/146 (6%)
Query: 116 KKGEDKTT--QKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKD 173
KKG D+ T +D E+K+ K K+ + KG+ D +K+ +K K+ G +
Sbjct: 191 KKGSDRNTGLSRDKDKKREEMKEVAK--KEDDEKVKGERRNTDTRKEGEKMKR---AGGN 245
Query: 174 SATESEDEK---GGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDS 230
+ + EDEK G D KKD + K + + + T+ K+ K +
Sbjct: 246 TDMKKEDEKVKRGTGNTDTKKDDEKVKKNEPLHEKEAKDDSKTKTPEKQTPSGPTKPSEG 305
Query: 231 AIELQAVKADEKKDEDGKKDANKGDE 256
+++ A DE ++ N E
Sbjct: 306 PAKVEEEAAPSIFDEPLERVKNNDPE 331
Score = 32.0 bits (71), Expect = 0.84
Identities = 34/141 (24%), Positives = 53/141 (37%), Gaps = 21/141 (14%)
Query: 46 KRRSKPSQIRDNTVSIIDEEQLRGDRRQPLWMYRSLMRISERPSVYLAARRQPLKPTRTV 105
K K + + V+ EE+ +G R L R ++ +R+ +K
Sbjct: 170 KEAGKDGRGEERAVATKKEEEKKGSDRNT-----GLSRDKDK-------KREEMKEVAKK 217
Query: 106 EVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGK 165
E D K KGE + T + + G D KK + K D KKD +K K
Sbjct: 218 EDDEKV-----KGERRNTDTRKEGEKMKRAGGNTDMKKEDEKVKRGTGNTDTKKDDEKVK 272
Query: 166 KD----AEKGKDSATESEDEK 182
K+ ++ KD + EK
Sbjct: 273 KNEPLHEKEAKDDSKTKTPEK 293
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 73.6 bits (179), Expect = 3e-13
Identities = 71/274 (25%), Positives = 119/274 (43%), Gaps = 51/274 (18%)
Query: 116 KKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEK-----LDAKKDSKKGKKDAEK 170
K G DK ++ T + K KD + +EK +++K KKD+K+ KD
Sbjct: 1012 KDGPDKERKEKTKPERYKEKSSDKDKSEKSILEKCQKDKEFDKCFKEKKDTKEKHKDTH- 1070
Query: 171 GKDSATESEDEKGGAKKDNK---------KDKKDSNKGKDSA--------TESE------ 207
GKD ++ ++G KK+ +KKD KGK+ + ESE
Sbjct: 1071 GKDKERKASLDQGKEKKEKAFPGIISEDFSEKKDDKKGKEKSWYIADIFTDESEDDRDSC 1130
Query: 208 ---GEKGGTEKDSKK--GKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKK 262
G K G D + G ++ ++G+++ + K+ +K+ + +KD E +D +K
Sbjct: 1131 MGSGFKMGEASDLPRTDGLQEKEEGREAYASDRHRKSSDKQHPERQKDK----EPRDRRK 1186
Query: 263 DAKEIKKGKKDKKKPSSTDSDSKD--------DVKKESKKDATKDAK---KVAKKDTEKE 311
D G+ K+K + KD D K + D+T+D K K+ +K +K
Sbjct: 1187 DRGAADAGRDKKEKVFEKHKEKKDKESTEKYKDRKDRASVDSTQDKKNKQKLPEKAEKKH 1246
Query: 312 SADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKK 345
+A+ K +K K D K+ K K DA+K
Sbjct: 1247 AAEDKAKSKHKEKSD--KEHSKERKSSRSADAEK 1278
Score = 69.7 bits (169), Expect = 4e-12
Identities = 76/312 (24%), Positives = 134/312 (42%), Gaps = 25/312 (8%)
Query: 46 KRRSKPSQIRDNTVSIIDEEQLRGDRRQPLWMYRSLMRISERPSVYLAARRQPLKPTRTV 105
++ S+ + + + ++EE L R S +ISE S R Q T +
Sbjct: 1268 RKSSRSADAEKSLLEKLEEEALHEYRED------SNDKISEVSSDSFTDRGQEPGLTAFL 1321
Query: 106 EVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKK---DSK 162
EV K + + + + SKK D E+ K+EK + K+ D K
Sbjct: 1322 EVSFTEPPGDDKPRESACLPEKLKEKERHRHSSSSSKKSHDRERAKKEKAEKKEKGEDYK 1381
Query: 163 KGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDS-NKGKDSATESEGEKGGTEKD-SKKG 220
+G + G+ E + G + K D +D +K + + + +K +E++ SKK
Sbjct: 1382 EGGSRKDSGQYEKDFLEADAYGVSYNMKADIEDELDKTIELFSTEKKDKNDSEREPSKKI 1441
Query: 221 KKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDA------KEIKKGKKDK 274
+K+ K SAI + +K +K+++ +K ++ + +D D E+ + +D+
Sbjct: 1442 EKELKPYGSSAINI--LKEKKKREKHREKWRDEKERHRDRHADGLLRHHRDELLRHHRDE 1499
Query: 275 KKPSSTDSDSKDDVKKESKKD-----ATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKK 329
+KP++ D DS V K+ +D K+ K EKE D K + N K K
Sbjct: 1500 QKPATRDKDSPPRVLKDKSRDEGPRLGDAKLKEKFKDGAEKEKGDPVKMSNGNDKVAPSK 1559
Query: 330 D-AKKNAKKDEK 340
D KK+A+ EK
Sbjct: 1560 DPGKKDARPREK 1571
Score = 68.2 bits (165), Expect = 1e-11
Identities = 61/237 (25%), Positives = 100/237 (42%), Gaps = 17/237 (7%)
Query: 125 KDTTDSE-SELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESED--E 181
+D+ DS ++ + K DS +E KE+ + ++DS+ +K + + D +
Sbjct: 855 EDSWDSPVTDYRDMKSDSVAKLILETVKEDSKERRRDSRAREKRDYREPFFRKKDRDYLD 914
Query: 182 KGGAKKDNKKDKKDSNKG----KDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAV 237
K K+ + +K S G KD E G KD+ + K+ + G+ E
Sbjct: 915 KNSEKRKEQTEKHKSVPGYLSEKDKKRRESAEAGRDRKDALESCKERRDGRAKPEEAHRE 974
Query: 238 KADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDAT 297
+ E E G KD + GD K + E ++K+K D + K+ K E K+ +
Sbjct: 975 ELKECGCESGFKDKSDGDFGKGL--EPWERHHPAREKEKKDGPDKERKEKTKPERYKEKS 1032
Query: 298 KDAKKVAKKDTEKESADSKKDAKKNAKKDAK--------KDAKKNAKKDEKKDAKKK 346
D K K EK D + D KKD K KD ++ A D+ K+ K+K
Sbjct: 1033 SDKDKSEKSILEKCQKDKEFDKCFKEKKDTKEKHKDTHGKDKERKASLDQGKEKKEK 1089
Score = 62.0 bits (149), Expect = 8e-10
Identities = 76/365 (20%), Positives = 141/365 (38%), Gaps = 32/365 (8%)
Query: 2 SLPRFQRVNFGPYDNYIPVSELSKKSWNQQHFALLFPKPQRPGTKRRSKPSQIRDNTVSI 61
SL R + N ++ + S K+ ++ PK ++ + + + +D +
Sbjct: 717 SLKRIKDTNKDISRSFREEKDRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKL 776
Query: 62 IDEEQLRGDRRQPLWMYRSLMRISERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKG--- 118
+ L+ D+ IS+ ++ LK + DS E K
Sbjct: 777 EKKNDLKEDK------------ISKEKEKIFKEDKEKLKKEKVYREDSAFDEYCNKNQFL 824
Query: 119 EDKTTQKDTTDSE-----SELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKD 173
E++ T+ +D + S+L D K + + D K DS +D
Sbjct: 825 ENEDTKFSLSDDQRDRWFSDLSDSSFDFKGEDSWDSPVTDYRDMKSDSVAKLILETVKED 884
Query: 174 SATESEDEKGGAKKD------NKKDK----KDSNKGKDSATESEGEKGGTEKDSKKGKKD 223
S D + K+D KKD+ K+S K K+ + + G + KK ++
Sbjct: 885 SKERRRDSRAREKRDYREPFFRKKDRDYLDKNSEKRKEQTEKHKSVPGYLSEKDKKRRES 944
Query: 224 SKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSD 283
++ G+D L++ K E++D K + +E K+ ++ K D K
Sbjct: 945 AEAGRDRKDALESCK--ERRDGRAKPEEAHREELKECGCESGFKDKSDGDFGKGLEPWER 1002
Query: 284 SKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDA 343
+KE K K+ K+ K + KE + K ++K+ + +KD + + EKKD
Sbjct: 1003 HHPAREKEKKDGPDKERKEKTKPERYKEKSSDKDKSEKSILEKCQKDKEFDKCFKEKKDT 1062
Query: 344 KKKGK 348
K+K K
Sbjct: 1063 KEKHK 1067
Score = 59.3 bits (142), Expect = 5e-09
Identities = 55/224 (24%), Positives = 100/224 (44%), Gaps = 9/224 (4%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
DS+A E E +KD + ++ K+ ++K K + EK +++S + +D
Sbjct: 891 DSRAREKRDYREPFFRKKDRDYLDKNSEKRKEQTEKHKSVPGYLSEKDKKRRESAEAGRD 950
Query: 168 AEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGT----EKDSKKGKKD 223
+ +S E D + ++ ++++ K+ +S+G+ G E+ +K+
Sbjct: 951 RKDALESCKERRDGRAKPEEAHREELKECGCESGFKDKSDGDFGKGLEPWERHHPAREKE 1010
Query: 224 SKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKK--KPSSTD 281
K G D + + K + K++ KD ++ + +KD KE K K+KK K D
Sbjct: 1011 KKDGPDKERK-EKTKPERYKEKSSDKDKSEKSILEKCQKD-KEFDKCFKEKKDTKEKHKD 1068
Query: 282 SDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKK 325
+ KD +K S D K+ K+ A E KKD KK +K
Sbjct: 1069 THGKDKERKASL-DQGKEKKEKAFPGIISEDFSEKKDDKKGKEK 1111
Score = 58.5 bits (140), Expect = 8e-09
Identities = 62/251 (24%), Positives = 110/251 (43%), Gaps = 28/251 (11%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD 167
++ A++ +K DK Q + E + +KD + D + K+EK+ K KK K+
Sbjct: 1157 EAYASDRHRKSSDK--QHPERQKDKEPRDRRKD-RGAADAGRDKKEKVFEKHKEKKDKES 1213
Query: 168 AEKGKDSATESEDEKGGAKKDNKKDKKDSNK-----GKDSATESEGEKGGTEKDSKKGKK 222
EK K D K A D+ +DKK+ K K A E + + EK K+ K
Sbjct: 1214 TEKYK-------DRKDRASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSKHKEKSDKEHSK 1266
Query: 223 DSKKGKDSAIELQAV-KADEKKDEDGKKDANK--GDESKDAKKDAKEIKKGKKDKKKPSS 279
+ K + + E + K +E+ + ++D+N + S D+ D + + G + S
Sbjct: 1267 ERKSSRSADAEKSLLEKLEEEALHEYREDSNDKISEVSSDSFTDRGQ-EPGLTAFLEVSF 1325
Query: 280 TDSDSKDDVKKES--------KKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDA 331
T+ DD +ES +K+ + + +KK ++E A +K KK +D K+
Sbjct: 1326 TEPPG-DDKPRESACLPEKLKEKERHRHSSSSSKKSHDRERAKKEKAEKKEKGEDYKEGG 1384
Query: 332 KKNAKKDEKKD 342
+ +KD
Sbjct: 1385 SRKDSGQYEKD 1395
Score = 57.0 bits (136), Expect = 2e-08
Identities = 76/313 (24%), Positives = 115/313 (36%), Gaps = 77/313 (24%)
Query: 106 EVDSKAAEIGKKGEDKTTQKDTTDSESELKQGK---KDSKKGKDIEKGKEEKLDAKKDSK 162
E D K E + G D+ KD +S E + G+ +++ + + E G E K D
Sbjct: 936 EKDKKRRESAEAGRDR---KDALESCKERRDGRAKPEEAHREELKECGCESGFKDKSDGD 992
Query: 163 KGKKDAEKGKDSATESEDEKGGAKKDNKKDKK---------DSNKGKDSATE-----SEG 208
GK + +++K G K+ K+ K D +K + S E E
Sbjct: 993 FGKGLEPWERHHPAREKEKKDGPDKERKEKTKPERYKEKSSDKDKSEKSILEKCQKDKEF 1052
Query: 209 EKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKK----------DEDGKKDANKG---- 254
+K EK K K GKD + + EKK D KKD KG
Sbjct: 1053 DKCFKEKKDTKEKHKDTHGKDKERKASLDQGKEKKEKAFPGIISEDFSEKKDDKKGKEKS 1112
Query: 255 --------DESKDAKKDA-------------------KEIKKGKK-----------DKKK 276
DES+D + +E ++G++ DK+
Sbjct: 1113 WYIADIFTDESEDDRDSCMGSGFKMGEASDLPRTDGLQEKEEGREAYASDRHRKSSDKQH 1172
Query: 277 PS-STDSDSKDDVKKESKKDATKDAKKVA----KKDTEKESADSKKDAKKNAKKDAKKDA 331
P D + +D K DA +D K+ K+ +KES + KD K A D+ +D
Sbjct: 1173 PERQKDKEPRDRRKDRGAADAGRDKKEKVFEKHKEKKDKESTEKYKDRKDRASVDSTQDK 1232
Query: 332 KKNAKKDEKKDAK 344
K K EK + K
Sbjct: 1233 KNKQKLPEKAEKK 1245
Score = 57.0 bits (136), Expect = 2e-08
Identities = 59/241 (24%), Positives = 103/241 (42%), Gaps = 28/241 (11%)
Query: 128 TDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKK 187
TD E ++G++ + + ++ + +KD + + ++G A + EK K
Sbjct: 1146 TDGLQEKEEGREAYASDRHRKSSDKQHPERQKDKEPRDRRKDRGAADAGRDKKEKVFEKH 1205
Query: 188 DNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAV------KADE 241
KKDK+ + K KD K DS + KK+ +K + A + A K E
Sbjct: 1206 KEKKDKESTEKYKD-------RKDRASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSKHKE 1258
Query: 242 KKDEDGKKDANKGDESKDAKKDAKE------IKKGKKDKK-KPSSTDSDSKDDVKKESKK 294
K D++ K+ K S DA+K E + + ++D K S SDS D +E
Sbjct: 1259 KSDKEHSKE-RKSSRSADAEKSLLEKLEEEALHEYREDSNDKISEVSSDSFTDRGQEPGL 1317
Query: 295 DATKDAK--KVAKKDTEKESAD-----SKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKG 347
A + + D +ESA +K+ +++ +KK + K EK + K+KG
Sbjct: 1318 TAFLEVSFTEPPGDDKPRESACLPEKLKEKERHRHSSSSSKKSHDRERAKKEKAEKKEKG 1377
Query: 348 K 348
+
Sbjct: 1378 E 1378
Score = 55.1 bits (131), Expect = 9e-08
Identities = 62/238 (26%), Positives = 102/238 (42%), Gaps = 28/238 (11%)
Query: 130 SESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDN 189
SES+ + K + K +E + A KK + A D++G K +
Sbjct: 575 SESDYSSEGSSVESLKPVRKRQEHRKRASLSEKKSP--FLSSAEGAVPKLDKEGKVVKKH 632
Query: 190 KKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAI----------ELQAVKA 239
K K NK K + S+ K K +DSK+ D AI +L+ +K
Sbjct: 633 KTKHKHKNKEKGQCSISQELK---LKSFTYEYEDSKQKSDKAILLENDLSTENKLKVLKH 689
Query: 240 DE---KKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDA 296
D KK+E K K +E + KD K +K+ K K S + + KD K K+ +
Sbjct: 690 DRDHFKKEE--KLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKDRSNKAEKERS 747
Query: 297 TKDAK------KVAKKDTEKESAD--SKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
K+ ++ K++ +K+S D SK + K + K+D K+ K++K+ KK+
Sbjct: 748 LKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKEDKISKEKEKIFKEDKEKLKKE 805
Score = 53.9 bits (128), Expect = 2e-07
Identities = 61/259 (23%), Positives = 106/259 (40%), Gaps = 19/259 (7%)
Query: 97 QPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTT----DSESELKQGKKDSKKGKDIEKGK- 151
+ LKP R + K A + +K + + D E ++ + K K K+ EKG+
Sbjct: 587 ESLKPVRKRQEHRKRASLSEKKSPFLSSAEGAVPKLDKEGKVVKKHKTKHKHKNKEKGQC 646
Query: 152 ----EEKLDA---KKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSAT 204
E KL + + + K K D ++ +E++ K D KK+ K
Sbjct: 647 SISQELKLKSFTYEYEDSKQKSDKAILLENDLSTENKLKVLKHDRDHFKKEEKLSKMKLE 706
Query: 205 ESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDA 264
E E KD K K+ KD + + K K E + K + + +
Sbjct: 707 EKEW----LFKDEKSLKRIKDTNKDISRSFREEKDRSNKAEKERSLKEKSPKEEKLRLYK 762
Query: 265 KEIKKGKKDKKKPSSTDSDSKDD-VKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNA 323
+E KK KD+ +D K+D + KE +K +D +K+ K+ +E DS D N
Sbjct: 763 EERKKKSKDRPSKLEKKNDLKEDKISKEKEKIFKEDKEKLKKEKVYRE--DSAFDEYCNK 820
Query: 324 KKDAKKDAKKNAKKDEKKD 342
+ + + K + D+++D
Sbjct: 821 NQFLENEDTKFSLSDDQRD 839
Score = 53.5 bits (127), Expect = 3e-07
Identities = 61/273 (22%), Positives = 105/273 (38%), Gaps = 29/273 (10%)
Query: 96 RQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKL 155
RQ K R D AA+ G+ ++K +K + E + KD K ++ +++K
Sbjct: 1175 RQKDKEPRDRRKDRGAADAGRDKKEKVFEKHKEKKDKESTEKYKDRKDRASVDSTQDKKN 1234
Query: 156 DAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKG--KDSATESEGEKGGT 213
K K KK A +D A EK + K++ K++K S + S E E+
Sbjct: 1235 KQKLPEKAEKKHA--AEDKAKSKHKEK--SDKEHSKERKSSRSADAEKSLLEKLEEEALH 1290
Query: 214 EKDSKKGKKDSKKGKDS--------------AIELQAVKADEKKDEDG-----KKDANKG 254
E K S+ DS + D+K E K+ +
Sbjct: 1291 EYREDSNDKISEVSSDSFTDRGQEPGLTAFLEVSFTEPPGDDKPRESACLPEKLKEKERH 1350
Query: 255 DESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESAD 314
S + K + + ++ KK+K + D K+ S+KD+ + K + D S +
Sbjct: 1351 RHSSSSSKKSHDRERAKKEKAEKKEKGEDYKEG---GSRKDSGQYEKDFLEADAYGVSYN 1407
Query: 315 SKKDAKKNAKKDAKK-DAKKNAKKDEKKDAKKK 346
K D + K + +K K D +++ KK
Sbjct: 1408 MKADIEDELDKTIELFSTEKKDKNDSEREPSKK 1440
Score = 50.4 bits (119), Expect = 2e-06
Identities = 76/333 (22%), Positives = 128/333 (38%), Gaps = 31/333 (9%)
Query: 21 SELSKKSWNQQHFALLFPKPQRPGTKRRSKPSQIRDNTVSIIDEEQLRGDRRQPLWMYRS 80
S+ +KS ++QH K R K R RD + ++ + + D+ S
Sbjct: 1161 SDRHRKSSDKQHPERQKDKEPRDRRKDRGAADAGRDKKEKVFEKHKEKKDKE-------S 1213
Query: 81 LMRISERPSVYLAARRQPLKPTRTVEVDSKAAEIGKK---GEDKTTQKDTTDSESELKQG 137
+ +R R + T+ + K E +K EDK K S+ E +
Sbjct: 1214 TEKYKDRKD------RASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSKHKEKSDKEHSKE 1267
Query: 138 KKDSKKGKDIEKGKEEKLDA------KKDSKKGKKDAEKGKDSATESEDEKG--GAKKDN 189
+K S+ D EK EKL+ ++DS K +E DS T+ E G + +
Sbjct: 1268 RKSSRSA-DAEKSLLEKLEEEALHEYREDSND--KISEVSSDSFTDRGQEPGLTAFLEVS 1324
Query: 190 KKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEK-KDEDGK 248
+ +K ++SA E K EK+ + S K + KA++K K ED K
Sbjct: 1325 FTEPPGDDKPRESACLPEKLK---EKERHRHSSSSSKKSHDRERAKKEKAEKKEKGEDYK 1381
Query: 249 KDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDT 308
+ ++ D + K + G K D K ++K D+++ K
Sbjct: 1382 EGGSRKDSGQYEKDFLEADAYGVSYNMKADIEDELDKTIELFSTEKKDKNDSEREPSKKI 1441
Query: 309 EKESADSKKDAKKNAKKDAKKDAKKNAKKDEKK 341
EKE A K+ K++ + +DEK+
Sbjct: 1442 EKELKPYGSSAINILKEKKKREKHREKWRDEKE 1474
Score = 48.1 bits (113), Expect = 1e-05
Identities = 63/284 (22%), Positives = 107/284 (37%), Gaps = 21/284 (7%)
Query: 78 YRSLMRISERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQG 137
+R +SE+ S +L++ + K ++ KK + K K+ + + Q
Sbjct: 598 HRKRASLSEKKSPFLSSAEGAVPKL------DKEGKVVKKHKTKHKHKNKEKGQCSISQE 651
Query: 138 KK---------DSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESE---DEKGGA 185
K DSK+ D E L + K K D + K S+ +EK
Sbjct: 652 LKLKSFTYEYEDSKQKSDKAILLENDLSTENKLKVLKHDRDHFKKEEKLSKMKLEEKEWL 711
Query: 186 KKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDE 245
KD K K+ + KD + EK + K K+ K K+ + L + +K +
Sbjct: 712 FKDEKSLKRIKDTNKDISRSFREEKDRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKD 771
Query: 246 DGKKDANKGD--ESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKV 303
K K D E K +K+ K K+ K+ KK DS D + + K
Sbjct: 772 RPSKLEKKNDLKEDKISKEKEKIFKEDKEKLKKEKVYREDSAFDEYCNKNQFLENEDTKF 831
Query: 304 AKKDTEKESADSK-KDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
+ D +++ S D+ + K + D+ +D K D+ K
Sbjct: 832 SLSDDQRDRWFSDLSDSSFDFKGEDSWDSPVTDYRDMKSDSVAK 875
Score = 43.9 bits (102), Expect = 2e-04
Identities = 78/379 (20%), Positives = 137/379 (36%), Gaps = 58/379 (15%)
Query: 15 DNYIPVSELSKKSWNQQHFALLFPKPQRPGTKRRSKPSQIRDNTVSIIDEEQLRGDRRQP 74
+++I + ++ KS+ + + P++ + S S D +V++ E+LR
Sbjct: 378 NSFISIPKMEVKSYTKNNTIA----PKKASHRILSDTSDEEDASVTVGTGEKLRLSAHTI 433
Query: 75 LWMYRSLMRISERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESEL 134
L + E + + +K R E + GK+ DK ++ SE
Sbjct: 434 L----PGSKTREPSNAKQQKEKNKVKKKRKKETKGREVRFGKRS-DKFCSSESESESSES 488
Query: 135 KQGKKDSKKGKDIEKGKE---------EKLDAKKDSKKGKKDAEKGKDSATESEDEKGGA 185
+ +DS KG L A S G A+K S T+ +
Sbjct: 489 GEDDRDSLGSSGCLKGSPLVLKDPSLFSSLSASSTSSHGSSAAQKQNPSHTDQHTKHW-- 546
Query: 186 KKDNKK--------------DKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKG---- 227
+ DN K D + +S SEG + K +K ++ K+
Sbjct: 547 RTDNWKTISSPAWSEVSSLSDSTRTRLTSESDYSSEGSSVESLKPVRKRQEHRKRASLSE 606
Query: 228 KDSAIELQAVKADEKKDEDGK-----------KDANKGDESKDAKKDAKEIKKGKKDKKK 276
K S A A K D++GK K+ KG S + K +D K+
Sbjct: 607 KKSPFLSSAEGAVPKLDKEGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFTYEYEDSKQ 666
Query: 277 PSSTDSDSKDDVKKESK-------KDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKK 329
S ++D+ E+K +D K +K++K E++ K + KD K
Sbjct: 667 KSDKAILLENDLSTENKLKVLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTNK 726
Query: 330 DAKKNAKKDEKKDAKKKGK 348
D ++ + E+KD K +
Sbjct: 727 DISRSFR--EEKDRSNKAE 743
Score = 40.8 bits (94), Expect = 0.002
Identities = 45/200 (22%), Positives = 84/200 (42%), Gaps = 30/200 (15%)
Query: 126 DTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGA 185
D +++SE ++G K K + +K KD + +D E+ + D+K
Sbjct: 315 DGNNTDSEFEKGLKHKAKNPEPQKATAPV----KDEYEFDEDDEQDR---VPPVDDKHLL 367
Query: 186 KKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDE 245
KKD +K+ K ++ E K T+ ++ KK S + + +D +E
Sbjct: 368 KKDYRKETKSNSFISIPKMEV---KSYTKNNTIAPKKASHR----------ILSDTSDEE 414
Query: 246 DGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDAT-------K 298
D G++ + A I G K ++ ++ K+ VKK+ KK+ K
Sbjct: 415 DASVTVGTGEK---LRLSAHTILPGSKTREPSNAKQQKEKNKVKKKRKKETKGREVRFGK 471
Query: 299 DAKKVAKKDTEKESADSKKD 318
+ K ++E ES++S +D
Sbjct: 472 RSDKFCSSESESESSESGED 491
Score = 36.2 bits (82), Expect = 0.045
Identities = 54/253 (21%), Positives = 90/253 (35%), Gaps = 37/253 (14%)
Query: 112 AEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEE-KLDAKKDSKKGKKDAEK 170
AE+ KG D T + K K + G + ++ + + K + +
Sbjct: 225 AEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLLL 284
Query: 171 GKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDS 230
GK + T SE+ + + + A S + T+ + +KG K K +
Sbjct: 285 GKGTYTSSEE--------SSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKNPEP 336
Query: 231 AIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKK 290
VK + + DED ++D + K +KK + + K +S S K +VK
Sbjct: 337 QKATAPVKDEYEFDEDDEQDRVPPVDDKHL------LKKDYRKETKSNSFISIPKMEVKS 390
Query: 291 ESKKD--ATKDAKKVAKKDTEKES--------------------ADSKKDAKKNAKKDAK 328
+K + A K A DT E SK NAK+ +
Sbjct: 391 YTKNNTIAPKKASHRILSDTSDEEDASVTVGTGEKLRLSAHTILPGSKTREPSNAKQQKE 450
Query: 329 KDAKKNAKKDEKK 341
K+ K +K E K
Sbjct: 451 KNKVKKKRKKETK 463
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 73.2 bits (178), Expect = 3e-13
Identities = 36/197 (18%), Positives = 115/197 (58%), Gaps = 6/197 (3%)
Query: 152 EEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKG 211
E + + K+++ +GK + E+ +D E E++ +++N+ ++D ++ +D T+ E E+
Sbjct: 2 ERQRERKRETDRGK-ETERERDRQRERENQ---TERENRHRQRDRHRERDRQTDREKERE 57
Query: 212 GTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDE-DGKKDANKGDESK-DAKKDAKEIKK 269
++ ++ +++ + +++ + + + E+K + D ++D ++ E K + ++ + +K
Sbjct: 58 RQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRK 117
Query: 270 GKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKK 329
G +++ K + + D + + +++ +++ + ++ + D E++ +++ KK KK+ KK
Sbjct: 118 GGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKK 177
Query: 330 DAKKNAKKDEKKDAKKK 346
+ K+ K++++++ KK+
Sbjct: 178 ERKEKKKEEKRREDKKR 194
Score = 50.4 bits (119), Expect = 2e-06
Identities = 39/197 (19%), Positives = 97/197 (49%), Gaps = 26/197 (13%)
Query: 117 KGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGK-KDAEKGKDSA 175
+G++ ++D E E + +++ + +D + ++ + D +K+ ++ K +D ++ ++
Sbjct: 13 RGKETERERDR-QRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERE 71
Query: 176 TESEDEKGGAKKDNKKDKKDSNKGKDSATESE-----------GEKGGTEKDSKKGKKDS 224
TE E E+ ++ ++ K+ +++ +D + E KGG E+D K +
Sbjct: 72 TERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERD-----KQT 126
Query: 225 KKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDS 284
++ +D E Q + E++ + +K + + A+++ ++ K+ KK++KK
Sbjct: 127 ERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERK-KERKKERKK-------E 178
Query: 285 KDDVKKESKKDATKDAK 301
+ + KKE K+ K K
Sbjct: 179 RKEKKKEEKRREDKKRK 195
Score = 30.0 bits (66), Expect = 3.2
Identities = 16/81 (19%), Positives = 45/81 (55%), Gaps = 5/81 (6%)
Query: 115 GKKGEDKTTQKDTTDSESELKQGKKDSKKGKD--IEKGKEEKLDAKKDSKKGKKDAEKGK 172
G + DK T+++ +Q +++ ++ ++ E +E + A+++ +K ++ E+ K
Sbjct: 118 GGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKK 177
Query: 173 DSATESEDEKGGAKKDNKKDK 193
+ + ++EK ++++KK K
Sbjct: 178 ERKEKKKEEK---RREDKKRK 195
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 72.4 bits (176), Expect = 6e-13
Identities = 65/255 (25%), Positives = 111/255 (43%), Gaps = 57/255 (22%)
Query: 119 EDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGK-KDAEKGKDSATE 177
E+KT + + + +LK+ K K K+ ++ +E + D KD K K K EK KD T
Sbjct: 510 EEKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKET- 568
Query: 178 SEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAV 237
+ K K+ K+++ D K K E + D K KD V
Sbjct: 569 GRETKYPWKEFLKEEEADPYKFKIKEFE--------DVDPKVKLKDG-----------LV 609
Query: 238 KADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKK--------------------- 276
+ +++K +D KKD KG + KD ++ K KG++DK K
Sbjct: 610 RKEKEKHKDKKKDREKGKKDKDKREKEKVKDKGREDKMKAPAPPLVLPPKELALPLFSPA 669
Query: 277 -----PSSTDS----------DSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKK 321
P+ S + K+ VK++ KK K+ KK +K+ EK+ + +K+ ++
Sbjct: 670 TASRVPAMLPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKRE 729
Query: 322 NAKKDAKKDAKKNAK 336
K++ +K+ K+ K
Sbjct: 730 REKREKEKEKHKHEK 744
Score = 51.6 bits (122), Expect = 1e-06
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 8/138 (5%)
Query: 214 EKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKD 273
EK + KK ++ + K ++++D + +KD NK D K+ ++K+ +KD
Sbjct: 511 EKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNK-----DKSKEKDKVKEKEKD 565
Query: 274 KKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKD--- 330
K+ T K+ +K+E K+ D + + D +K KD KKD
Sbjct: 566 KETGRETKYPWKEFLKEEEADPYKFKIKEFEDVDPKVKLKDGLVRKEKEKHKDKKKDREK 625
Query: 331 AKKNAKKDEKKDAKKKGK 348
KK+ K EK+ K KG+
Sbjct: 626 GKKDKDKREKEKVKDKGR 643
Score = 51.2 bits (121), Expect = 1e-06
Identities = 52/215 (24%), Positives = 86/215 (40%), Gaps = 54/215 (25%)
Query: 120 DKTTQKDTTDSESELKQGKKDSKKGKDI-----EKGKEEKLDAKKDSKKGKKDAE---KG 171
+K KD + + ++K+ +KD + G++ E KEE+ D K K +D + K
Sbjct: 545 EKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLKEEEADPYKFKIKEFEDVDPKVKL 604
Query: 172 KDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKG---- 227
KD E EK KD KKD++ K KD K EK KG++D K
Sbjct: 605 KDGLVRKEKEK---HKDKKKDREKGKKDKD--------KREKEKVKDKGREDKMKAPAPP 653
Query: 228 -----KDSAIEL--------------------------QAVKADEKKDEDGKKDANKGDE 256
K+ A+ L + K EK+ + KK+ K E
Sbjct: 654 LVLPPKELALPLFSPATASRVPAMLPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKE 713
Query: 257 SKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKE 291
+ KK+ + K+ ++ +K+ + + +K E
Sbjct: 714 KEKEKKEKEREKEKREREKREKEKEKHKHEKIKVE 748
Score = 30.8 bits (68), Expect = 1.9
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 9/73 (12%)
Query: 98 PLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDA 157
P+ P + E K E KK +DK E + K+ K+ KK K+ EK K E+
Sbjct: 683 PVLPEKLFEEKEKVKEKEKK-KDK--------KEKKKKKEKEKEKKEKEREKEKREREKR 733
Query: 158 KKDSKKGKKDAEK 170
+K+ +K K + K
Sbjct: 734 EKEKEKHKHEKIK 746
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 72.0 bits (175), Expect = 7e-13
Identities = 62/210 (29%), Positives = 97/210 (46%), Gaps = 14/210 (6%)
Query: 138 KKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDE--KGGAKKDNKKDKKD 195
+KD G K K+ + DSK+ K K S +E + GAK+ + K+
Sbjct: 296 QKDLASGAVPTNLKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKE 355
Query: 196 SNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDA---- 251
K + A ES +EK +K K + +S+ L+A K KD+ GKK
Sbjct: 356 LAKTEKKAKES------SEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKI 409
Query: 252 NKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKE 311
+K +E KD K+ KEIKK +K+ KK + KD K+E +KD + KK++K D +
Sbjct: 410 SKLEEKKD--KEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPF 467
Query: 312 SADSKKDAKKNAKKDAKKDAKKNAKKDEKK 341
+ + +K K K + A + EK+
Sbjct: 468 TPEVRKTLYKAKVPGRVKIDRSRAIRGEKE 497
Score = 59.7 bits (143), Expect = 4e-09
Identities = 65/228 (28%), Positives = 109/228 (47%), Gaps = 21/228 (9%)
Query: 119 EDKTT-QKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATE 177
+D+T+ QK + + E+ Q K + + K++ + K+ + K ++ K +A K +D A E
Sbjct: 1350 KDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALE 1409
Query: 178 SEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKD-SKKGKDSAIELQA 236
+ + +KD ++KD E +K +KD +KD + + KD+A+E Q
Sbjct: 1410 QKG-RDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALE-QK 1467
Query: 237 VKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDK---KKPSSTDSDSKDDVKKESK 293
KA E KD+D E KD + KE +KDK +K S + + +D E K
Sbjct: 1468 DKALEPKDKD--------LEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMK 1519
Query: 294 KDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNA--KKDE 339
+D ++ K +K A +KD K + KKD + K A +KDE
Sbjct: 1520 ---DRDLEQTDKAPEQKHQAQEQKD-KVSEKKDQALEQKYWALGQKDE 1563
Score = 56.2 bits (134), Expect = 4e-08
Identities = 50/173 (28%), Positives = 81/173 (46%), Gaps = 15/173 (8%)
Query: 179 EDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIEL--QA 236
+D GA N K K + + K K +K+ + + K++ EL +
Sbjct: 297 KDLASGAVPTNLKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKEL 356
Query: 237 VKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDA 296
K ++K E +K K + + K ++ E K +K K KD V K+ K+
Sbjct: 357 AKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKL--------IKDKVGKKHLKE- 407
Query: 297 TKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEK-KDAKKKGK 348
K +K KKD EK+ + KK+ K+ K + +K+ KK+AKK+EK KD K + K
Sbjct: 408 -KISKLEEKKDKEKK--EIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELK 457
Score = 53.9 bits (128), Expect = 2e-07
Identities = 64/267 (23%), Positives = 122/267 (45%), Gaps = 17/267 (6%)
Query: 95 RRQPLKPTRTVEVDSKAAEIGKKGEDKTT---QKDTT---DSESELKQGKKDSKKGKDIE 148
+++P ++ K E + E K T QKD +E+ +Q K +KG+D+E
Sbjct: 1357 KKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLE 1416
Query: 149 KGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSN-KGKDSATESE 207
+ K+ L+ K + + K + KD A E +D K +KD ++KD+ + KD A E +
Sbjct: 1417 Q-KDTALEQKDKALEPKDKDLEEKDKALEQKD-KIPEEKDKALEQKDTALEQKDKALEPK 1474
Query: 208 GEKGGTEKDSKKGKKDS-KKGKDSAIELQAVKADEKKDED-----GKKDANKGDESKDAK 261
+K +KD +K+ + KD A++ + + K ED +D + D++ + K
Sbjct: 1475 -DKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQK 1533
Query: 262 KDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKK 321
A+E +K K +KK + + +K+ + A + + E+ES + +K
Sbjct: 1534 HQAQE-QKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRK 1592
Query: 322 NAKKDAKKDAKKNAKKDEKKDAKKKGK 348
+ K K A +++ + +K K
Sbjct: 1593 PKMLEEKSPEKVKAMEEKLEALLEKTK 1619
Score = 47.4 bits (111), Expect = 2e-05
Identities = 58/239 (24%), Positives = 102/239 (42%), Gaps = 32/239 (13%)
Query: 82 MRISERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDS 141
++ + + +V A+R+ + E S+ A+ K E K K++++ E K K +
Sbjct: 323 LKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKA--KESSEKPPE-KPAKPER 379
Query: 142 KKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKD 201
K + E K EK KD K GKK K+ ++ E++K KK+ KK++K+ K
Sbjct: 380 VKTESSEALKAEKRKLIKD-KVGKKHL---KEKISKLEEKKDKEKKEIKKERKELKK--- 432
Query: 202 SATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKK--DEDGKKDANKGDESKD 259
EG K+ KK K +K KD+ EL+ + + K + +K K
Sbjct: 433 ----DEG-----RKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGR 483
Query: 260 AKKDAKEIKKGKKDKKKPSSTDSDSKDDVK-----------KESKKDATKDAKKVAKKD 307
K D +G+K+ T K V S +D T+D +++ +++
Sbjct: 484 VKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREE 542
Score = 45.8 bits (107), Expect = 6e-05
Identities = 63/289 (21%), Positives = 112/289 (38%), Gaps = 41/289 (14%)
Query: 97 QPLKPTRTVEVDSKAAE----------IGKKGEDKTTQKDTTDSESELKQGKKDSKKGKD 146
+P KP R S+A + +GKK + K + E K+ KK+ K+ K
Sbjct: 373 KPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKK 432
Query: 147 IEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATES 206
E KEEK DAKK+ K+ E K S + + +K K K D +
Sbjct: 433 DEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAI 492
Query: 207 EGEKGGTEKDSKKGKKDSKKG------------------KDSAIELQAVKADEKKDEDGK 248
GEK E S+ ++KG +D + + +K +E+ +
Sbjct: 493 RGEK---ELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQ 549
Query: 249 KDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKES-------KKDATKD-- 299
+D GD+ + PS ++ V KE ++ +KD
Sbjct: 550 RDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRG 609
Query: 300 AKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
A+ + EK++ + KK + D + +A++ ++ + K+D +K +
Sbjct: 610 LDSGAETEEEKDTWEEKKQREAERLPD-RTEAREESEPEVKEDVIEKAE 657
>gi|195976782 Paf1/RNA polymerase II complex component [Homo
sapiens]
Length = 710
Score = 72.0 bits (175), Expect = 7e-13
Identities = 62/243 (25%), Positives = 105/243 (43%), Gaps = 20/243 (8%)
Query: 108 DSKAAEIGKKGEDKTTQKDTTDSESELKQGK-KDSKKGK--DIEKGKEEKLDAKKDSKKG 164
DS+ E ++ +T+DS+ E G K+ KKGK IEK K A K + G
Sbjct: 78 DSEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKARKIEKKGTMKKQANKTASSG 137
Query: 165 KKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDS 224
D KDS+ ES + G D+ + S+ DS++E E G +D ++D
Sbjct: 138 SSD----KDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEED- 192
Query: 225 KKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDS 284
+ ++ +++ +++ E ++ K EIKK K KK +
Sbjct: 193 -----------RARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKK 241
Query: 285 KDDVKKESKKDATKDAKKVAKKDTEKES-ADSKKDAKKNAKKDAKKDAKKNAKKDEKKDA 343
K + ++E KK +V + E+ S D K D K A ++ K + +K + + A
Sbjct: 242 KQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLA 301
Query: 344 KKK 346
KK+
Sbjct: 302 KKQ 304
Score = 47.8 bits (112), Expect = 1e-05
Identities = 37/172 (21%), Positives = 75/172 (43%), Gaps = 10/172 (5%)
Query: 118 GEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGK--EEKLDAKKDSKKGKKDAEKGKDSA 175
GED ++ ++ + +++ + IEK + + + + KK K KK +K K
Sbjct: 183 GEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKK 242
Query: 176 TESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAI--E 233
E E EK + + NK + S + + +K + K +++ +K + + + +
Sbjct: 243 QEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAK 302
Query: 234 LQAVKA------DEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSS 279
Q +K DE+++ED K S+ + D +E K+ K +P S
Sbjct: 303 KQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRTSSSDEEEEKEEIPPKSQPVS 354
Score = 46.6 bits (109), Expect = 3e-05
Identities = 50/235 (21%), Positives = 92/235 (39%), Gaps = 25/235 (10%)
Query: 115 GKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDS 174
G++G TT + +DS ++++ +E L K + ++ E
Sbjct: 32 GRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLD---QELLSLAKRKRSDSEEKEPPVSQ 88
Query: 175 ATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIEL 234
S D + D + NK K A + E +KG +K + K KDS+ E
Sbjct: 89 PAASSDSETSDSDDEWTFGSNKNKKKGKARKIE-KKGTMKKQANKTASSGSSDKDSSAES 147
Query: 235 QAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKK 294
A + E D D ++ D D+ + +E G + D + + +++ ++K
Sbjct: 148 SAPEEGEVSDSDSNSSSSSSDS--DSSSEDEEFHDGYGEDLMG---DEEDRARLEQMTEK 202
Query: 295 DATKDA-KKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
+ ++ ++ K++ K + KK K AKK EKK +KK K
Sbjct: 203 EREQELFNRIEKREVLKRRFEIKKKLK-------------TAKKKEKK--EKKKK 242
Score = 37.4 bits (85), Expect = 0.020
Identities = 46/226 (20%), Positives = 83/226 (36%), Gaps = 58/226 (25%)
Query: 179 EDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKD--------SKKGKKDSKKGKDS 230
E GG ++ ++ + +S+ E G++++ +K+ + DS++ +
Sbjct: 26 EGSPGGGRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPP 85
Query: 231 AIELQAVKADEKKDEDG------------------------KKDANK----GDESKDAKK 262
+ A E D D KK ANK G KD+
Sbjct: 86 VSQPAASSDSETSDSDDEWTFGSNKNKKKGKARKIEKKGTMKKQANKTASSGSSDKDSSA 145
Query: 263 DAKEIKKGKKDKKKPSSTDSDSKDDVKKESK-------KDATKDAKKVAKKD--TEKESA 313
++ ++G+ +S+ S S D E + +D D + A+ + TEKE
Sbjct: 146 ESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKERE 205
Query: 314 DS-------------KKDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
+ + KK K KK+ K+ KK E++ KKK
Sbjct: 206 QELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKK 251
Score = 34.3 bits (77), Expect = 0.17
Identities = 38/165 (23%), Positives = 65/165 (39%), Gaps = 24/165 (14%)
Query: 65 EQLRGDRRQPLWMYRSLMRISERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQ 124
E L GD + + + E+ +R+ LK R E+ K + KK E K +
Sbjct: 184 EDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLK--RRFEIKKKL-KTAKKKEKKEKK 240
Query: 125 KDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKG-----KKDAEKGKDSATE-- 177
K + + + K + + K + K D K D K K + EK K+ E
Sbjct: 241 KKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELL 300
Query: 178 ------------SEDEKGGAKKDNKKDKKDSNKGKDSATESEGEK 210
S+DE+ ++D+K +K + S+++ E EK
Sbjct: 301 AKKQPLKTSEVYSDDEE--EEEDDKSSEKSDRSSRTSSSDEEEEK 343
>gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
sapiens]
Length = 530
Score = 71.6 bits (174), Expect = 1e-12
Identities = 71/286 (24%), Positives = 127/286 (44%), Gaps = 43/286 (15%)
Query: 81 LMRISERPSVYLAARRQPLKPTRT---VEVDSKAAEIGKKG---EDKTTQKDTTDS---- 130
L I P V ++++ K + VEV+ K + K+ E+K + +D T +
Sbjct: 81 LWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDIT 140
Query: 131 -ESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDN 189
++G+K K K +E + + S K ++G+ +ATE + K +
Sbjct: 141 TPKAARRGRK-RKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRP-- 197
Query: 190 KKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKK 249
K K+ D TE + K KKG+++ + K KKDE+G+K
Sbjct: 198 KMVKQPCPSESDIITEED-------KSKKKGQEEKQP-----------KKQPKKDEEGQK 239
Query: 250 DANKGDESKDAKKDAKEIKKGKKDKKKP---SSTDSDSKDDVKKESKKDA------TKDA 300
+ +K + D K+ KE++ +K+ K S++DS+ + D ++ KK T
Sbjct: 240 EEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHR 299
Query: 301 KKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
+ + K EKE+AD K+ K+ + + ++ K KK E K +KK
Sbjct: 300 RNMLKGQHEKEAADRKR--KQEEQMETEQQNKDEGKKPEVKKVEKK 343
Score = 61.6 bits (148), Expect = 1e-09
Identities = 58/233 (24%), Positives = 104/233 (44%), Gaps = 24/233 (10%)
Query: 132 SELKQGKKDSKKGKDIEKGKEEKLDAKKDS----KKGKKDAEKGKDSATESEDEKGGAKK 187
S + K S D+E ++E +K+D+ K +D K D T +G +K
Sbjct: 93 SSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRK 152
Query: 188 DNKKDKKDSNKGKDSATESEGEKGGTEKD---SKKGKKDSKKGKDSAIELQAV-KADEKK 243
K+ + + +AT S K ++ + + K +G+ ++ ++D
Sbjct: 153 AEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIIT 212
Query: 244 DEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKV 303
+ED K KG E K KK K+ ++G+K++ KP K+ KKE KK+ K +
Sbjct: 213 EED--KSKKKGQEEKQPKKQPKKDEEGQKEEDKP------RKEPDKKEGKKEVESKRKNL 264
Query: 304 AK------KDTEKESADSKKDAKKNAKKDAKKDAKKNAKK--DEKKDAKKKGK 348
AK D+E+E D + + K+ ++ + ++N K EK+ A +K K
Sbjct: 265 AKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRK 317
Score = 53.9 bits (128), Expect = 2e-07
Identities = 50/162 (30%), Positives = 81/162 (50%), Gaps = 16/162 (9%)
Query: 125 KDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGG 184
K SES++ + SKK KG+EEK KK KK ++ +K +D + D+K G
Sbjct: 201 KQPCPSESDIITEEDKSKK-----KGQEEK-QPKKQPKK-DEEGQKEEDKPRKEPDKKEG 253
Query: 185 AKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKD--SAIELQAVKAD-E 241
K+ K K + G S ++SE E D ++G+K K G++ +A +K E
Sbjct: 254 KKEVESKRKNLAKTGVTSTSDSE-----EEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHE 308
Query: 242 KKDEDGKKDANKGDESKDAKKD-AKEIKKGKKDKKKPSSTDS 282
K+ D K+ + E++ KD K+ + K +KK+ +S DS
Sbjct: 309 KEAADRKRKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMDS 350
Score = 36.2 bits (82), Expect = 0.045
Identities = 69/350 (19%), Positives = 134/350 (38%), Gaps = 99/350 (28%)
Query: 38 PKPQ-RPGTKRRSKPSQIRDNTVSIIDEEQLRG-DRRQPLWMYRSLMRISERPSVYLAAR 95
PKP+ RP ++ PS+ + ++ D+ + +G + +QP + + E R
Sbjct: 191 PKPRGRPKMVKQPCPSE--SDIITEEDKSKKKGQEEKQPK---KQPKKDEEGQKEEDKPR 245
Query: 96 RQPLKPTRTVEVDSKAAEIGKKG----EDKTTQKDTTDSESELKQGK------------- 138
++P K EV+SK + K G D + D + E + K G+
Sbjct: 246 KEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKG 305
Query: 139 KDSKKGKDIEKGKEEKLDAKKDSK-KGKKD----AEKGKDSATESE------DEKGGAKK 187
+ K+ D ++ +EE+++ ++ +K +GKK EK ++++ +S + K K
Sbjct: 306 QHEKEAADRKRKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMDSRLQRIHAEIKNSLKI 365
Query: 188 DN----------------------------------------------KKDKKDSNKGKD 201
DN +K NK K+
Sbjct: 366 DNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKN 425
Query: 202 SATESEGEKGGTE------------KDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKK 249
EG+ T+ +++ K K KKG + +E + + +
Sbjct: 426 MFLVGEGDSVITQVLNKSLAEQRQHEEANKTKDQGKKGPNKKLEKEQTGSKTLNGGSDAQ 485
Query: 250 DANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKD 299
D N+ + ++ +D+K+ + KKKPSS + ++ + S KD+T D
Sbjct: 486 DGNQPQHNGESNEDSKDNHEA-STKKKPSSEERET-----EISLKDSTLD 529
>gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
sapiens]
Length = 530
Score = 71.6 bits (174), Expect = 1e-12
Identities = 71/286 (24%), Positives = 127/286 (44%), Gaps = 43/286 (15%)
Query: 81 LMRISERPSVYLAARRQPLKPTRT---VEVDSKAAEIGKKG---EDKTTQKDTTDS---- 130
L I P V ++++ K + VEV+ K + K+ E+K + +D T +
Sbjct: 81 LWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDIT 140
Query: 131 -ESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDN 189
++G+K K K +E + + S K ++G+ +ATE + K +
Sbjct: 141 TPKAARRGRK-RKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRP-- 197
Query: 190 KKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKK 249
K K+ D TE + K KKG+++ + K KKDE+G+K
Sbjct: 198 KMVKQPCPSESDIITEED-------KSKKKGQEEKQP-----------KKQPKKDEEGQK 239
Query: 250 DANKGDESKDAKKDAKEIKKGKKDKKKP---SSTDSDSKDDVKKESKKDA------TKDA 300
+ +K + D K+ KE++ +K+ K S++DS+ + D ++ KK T
Sbjct: 240 EEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHR 299
Query: 301 KKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
+ + K EKE+AD K+ K+ + + ++ K KK E K +KK
Sbjct: 300 RNMLKGQHEKEAADRKR--KQEEQMETEQQNKDEGKKPEVKKVEKK 343
Score = 61.6 bits (148), Expect = 1e-09
Identities = 58/233 (24%), Positives = 104/233 (44%), Gaps = 24/233 (10%)
Query: 132 SELKQGKKDSKKGKDIEKGKEEKLDAKKDS----KKGKKDAEKGKDSATESEDEKGGAKK 187
S + K S D+E ++E +K+D+ K +D K D T +G +K
Sbjct: 93 SSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRK 152
Query: 188 DNKKDKKDSNKGKDSATESEGEKGGTEKD---SKKGKKDSKKGKDSAIELQAV-KADEKK 243
K+ + + +AT S K ++ + + K +G+ ++ ++D
Sbjct: 153 AEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIIT 212
Query: 244 DEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKV 303
+ED K KG E K KK K+ ++G+K++ KP K+ KKE KK+ K +
Sbjct: 213 EED--KSKKKGQEEKQPKKQPKKDEEGQKEEDKP------RKEPDKKEGKKEVESKRKNL 264
Query: 304 AK------KDTEKESADSKKDAKKNAKKDAKKDAKKNAKK--DEKKDAKKKGK 348
AK D+E+E D + + K+ ++ + ++N K EK+ A +K K
Sbjct: 265 AKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRK 317
Score = 53.9 bits (128), Expect = 2e-07
Identities = 50/162 (30%), Positives = 81/162 (50%), Gaps = 16/162 (9%)
Query: 125 KDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGG 184
K SES++ + SKK KG+EEK KK KK ++ +K +D + D+K G
Sbjct: 201 KQPCPSESDIITEEDKSKK-----KGQEEK-QPKKQPKK-DEEGQKEEDKPRKEPDKKEG 253
Query: 185 AKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKD--SAIELQAVKAD-E 241
K+ K K + G S ++SE E D ++G+K K G++ +A +K E
Sbjct: 254 KKEVESKRKNLAKTGVTSTSDSE-----EEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHE 308
Query: 242 KKDEDGKKDANKGDESKDAKKD-AKEIKKGKKDKKKPSSTDS 282
K+ D K+ + E++ KD K+ + K +KK+ +S DS
Sbjct: 309 KEAADRKRKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMDS 350
Score = 36.2 bits (82), Expect = 0.045
Identities = 69/350 (19%), Positives = 134/350 (38%), Gaps = 99/350 (28%)
Query: 38 PKPQ-RPGTKRRSKPSQIRDNTVSIIDEEQLRG-DRRQPLWMYRSLMRISERPSVYLAAR 95
PKP+ RP ++ PS+ + ++ D+ + +G + +QP + + E R
Sbjct: 191 PKPRGRPKMVKQPCPSE--SDIITEEDKSKKKGQEEKQPK---KQPKKDEEGQKEEDKPR 245
Query: 96 RQPLKPTRTVEVDSKAAEIGKKG----EDKTTQKDTTDSESELKQGK------------- 138
++P K EV+SK + K G D + D + E + K G+
Sbjct: 246 KEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKG 305
Query: 139 KDSKKGKDIEKGKEEKLDAKKDSK-KGKKD----AEKGKDSATESE------DEKGGAKK 187
+ K+ D ++ +EE+++ ++ +K +GKK EK ++++ +S + K K
Sbjct: 306 QHEKEAADRKRKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMDSRLQRIHAEIKNSLKI 365
Query: 188 DN----------------------------------------------KKDKKDSNKGKD 201
DN +K NK K+
Sbjct: 366 DNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKN 425
Query: 202 SATESEGEKGGTE------------KDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKK 249
EG+ T+ +++ K K KKG + +E + + +
Sbjct: 426 MFLVGEGDSVITQVLNKSLAEQRQHEEANKTKDQGKKGPNKKLEKEQTGSKTLNGGSDAQ 485
Query: 250 DANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKD 299
D N+ + ++ +D+K+ + KKKPSS + ++ + S KD+T D
Sbjct: 486 DGNQPQHNGESNEDSKDNHEA-STKKKPSSEERET-----EISLKDSTLD 529
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 71.6 bits (174), Expect = 1e-12
Identities = 42/257 (16%), Positives = 133/257 (51%), Gaps = 22/257 (8%)
Query: 95 RRQPLKPTRTVEVDSKAAEIGKKGEDKTT-----QKDTTDSESELKQGKKDSKKGKDIEK 149
R++ + R E + + G++G D+ T ++ D+E E ++ + D ++ + E+
Sbjct: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKE-RERQTDRERQRQTER 173
Query: 150 GKEEKLDAKKD-SKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEG 208
++++ + +K+ ++ +++ ++ K++ TE + G +++ +++ + + K
Sbjct: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERD 233
Query: 209 EKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIK 268
+ TE++ +K + + +A E++ E K+ + D +D + KE +
Sbjct: 234 RQRKTEREREK-------------QAERERASERETERDKERERERDRDRDRDRRQKE-R 279
Query: 269 KGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAK 328
+ + D+K+ T+ D + + K+E +++ ++ ++ K++ E+E + +++ ++ ++D +
Sbjct: 280 ERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERE-RERERERQRETERDRE 338
Query: 329 KDAKKNAKKDEKKDAKK 345
K+ ++ K+ + D ++
Sbjct: 339 KERERKRKRQTEMDRER 355
Score = 70.9 bits (172), Expect = 2e-12
Identities = 46/240 (19%), Positives = 121/240 (50%), Gaps = 24/240 (10%)
Query: 116 KKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKD-----SKKGKKDAEK 170
+K ++ T+++ G+++ ++ +D EK +E + D ++ +++ +++ EK
Sbjct: 124 QKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREK 183
Query: 171 GKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDS 230
+ E E ++ +K+NK + + S +G++ E E E K ++D ++ +
Sbjct: 184 NRQERRERERQR---EKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTER 240
Query: 231 AIELQAVK--ADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDV 288
E QA + A E++ E K+ + D +D + KE ++ + D+K+ T+ D + +
Sbjct: 241 EREKQAERERASERETERDKERERERDRDRDRDRRQKE-RERQTDRKRQRRTERDRETER 299
Query: 289 KKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
K+E ++ + E+E ++K ++ +++ +++ ++ ++D +K+ ++K K
Sbjct: 300 KRERQR------------ERERERERNRK-RERERERERERERQRETERDREKERERKRK 346
Score = 64.3 bits (155), Expect = 2e-10
Identities = 48/247 (19%), Positives = 129/247 (52%), Gaps = 34/247 (13%)
Query: 116 KKGEDKTTQKDTTDSESELKQGKKDSK-----------KGKDIEKGKEEKLDAKKDSKKG 164
+K ++ +K T+ E++ K+ ++ K + +D EK +E + D ++D ++
Sbjct: 59 QKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQRE 118
Query: 165 K-KDAEKGKDSATESEDEKGGAKKDN----KKDKKDSNKGKDSATESEGEKGGTEKDSKK 219
K ++ +K ++ TE E E+G ++ + ++ ++D+ K ++ T+ E ++ TE++ +K
Sbjct: 119 KERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQ-TERNRQK 177
Query: 220 GKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSS 279
+++ +K + E + + E K ED + + +G E + ++ E ++K+ +
Sbjct: 178 -EREREKNRQERRERERQREKENKTED--RHSERGRERERERETETET-----ERKRQTD 229
Query: 280 TDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDE 339
+ D + ++E +K A ++ + ++++TE +D ++ ++D +D + K+ E
Sbjct: 230 RERDRQRKTEREREKQAERE--RASERETE-------RDKERERERDRDRDRDRRQKERE 280
Query: 340 KKDAKKK 346
++ +K+
Sbjct: 281 RQTDRKR 287
Score = 62.0 bits (149), Expect = 8e-10
Identities = 47/325 (14%), Positives = 154/325 (47%), Gaps = 23/325 (7%)
Query: 44 GTKRRSKPSQIRDNTVSIIDEEQLRGDRRQPLWMYRSLMRISERPSVYLAARRQPLKPTR 103
G R++ + R+ E + + DR + R+ + ER R + + +
Sbjct: 138 GRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREK 197
Query: 104 TVEVDSKAAEIGKKGE------DKTTQKDTTDSESEL---------KQGKKDSKKGKDIE 148
+ + + +E G++ E +T +K TD E + KQ +++ ++ E
Sbjct: 198 ENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETE 257
Query: 149 KGKEEKLDAKKDSKKGKKDAEKGKDSATE----SEDEKGGAKKDNKKDKKDSNKGKDSAT 204
+ KE + + +D + ++ E+ + + + +E ++ +K ++ +++ + ++
Sbjct: 258 RDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKR 317
Query: 205 ESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDA 264
E E E+ + ++ ++D +K ++ + Q E+ + G++ + + ++ +++
Sbjct: 318 ERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERE- 376
Query: 265 KEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKE-SADSKKDAKKNA 323
++ + ++ +++ D D + + +++++KD +D ++ +K E+E +S++ ++
Sbjct: 377 RDRQSAREREERERDRDRDRQKERERQTEKD--RDGQRETEKQREREKDRESERGRERGR 434
Query: 324 KKDAKKDAKKNAKKDEKKDAKKKGK 348
+++ +K +++ ++ + A ++ K
Sbjct: 435 EREKQKGRERDRERQTDRQAGRQRK 459
Score = 60.8 bits (146), Expect = 2e-09
Identities = 31/214 (14%), Positives = 117/214 (54%), Gaps = 7/214 (3%)
Query: 134 LKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDK 193
L Q KD+ G D E+ ++++ + +++ ++ +++ ++ ++ E + + K+D +++
Sbjct: 42 LGQAHKDAD-GDDRERNRQKERERRREKRQTERETDRKRERRREKDRHR---KRDRHRER 97
Query: 194 -KDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDAN 252
+D K ++ T+ E ++ EK+ + K+ ++ + + + D +++ + ++DA
Sbjct: 98 QRDREKERERQTDRERDRQ-REKERNRQKERERETEREGERGRDRQTDGQRERERQRDAE 156
Query: 253 KGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKES 312
K E + ++ ++ ++ ++ +++ + ++ ++ K++ T+D ++ E+E
Sbjct: 157 KERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERE- 215
Query: 313 ADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
+++ + ++ + D ++D ++ +++ +K A+++
Sbjct: 216 RETETETERKRQTDRERDRQRKTEREREKQAERE 249
Score = 60.1 bits (144), Expect = 3e-09
Identities = 34/221 (15%), Positives = 111/221 (50%), Gaps = 5/221 (2%)
Query: 116 KKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKD--AEKGKD 173
K+ E + + T+ + E ++ ++D + +D + + E+ +K ++ ++D E+ ++
Sbjct: 244 KQAERERASERETERDKE-RERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRE 302
Query: 174 SATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIE 233
E E E+ +K ++ +++ + + TE + EK K ++ + D ++ + + E
Sbjct: 303 RQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGRE 362
Query: 234 LQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESK 293
+ +A+ +++ + ++D E ++ ++D ++ +++++ D + + ++E +
Sbjct: 363 GRR-QAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRERE 421
Query: 294 KDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKN 334
KD + + ++ EK+ ++D ++ + A + K++
Sbjct: 422 KDRESERGRERGREREKQKG-RERDRERQTDRQAGRQRKRS 461
Score = 40.8 bits (94), Expect = 0.002
Identities = 22/161 (13%), Positives = 79/161 (49%), Gaps = 12/161 (7%)
Query: 195 DSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKG 254
D ++ + + ES +G + D ++ + E + K +++ D K++ +
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRR- 83
Query: 255 DESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEK---- 310
++ + K+D ++ ++K++ TD + D ++E +++ K+ ++ +++ E+
Sbjct: 84 EKDRHRKRDRHRERQRDREKERERQTDRER--DRQREKERNRQKERERETEREGERGRDR 141
Query: 311 -----ESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
+ ++DA+K ++ ++ ++ +++ +K+ +++
Sbjct: 142 QTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERERE 182
Score = 34.7 bits (78), Expect = 0.13
Identities = 28/170 (16%), Positives = 75/170 (44%), Gaps = 11/170 (6%)
Query: 41 QRPGTKRRSKPSQIRDNTVSIIDEEQLRGDRRQPLWMYRSLMRISERPSVYLAARRQPLK 100
+R ++R + + N + E+ R RQ R R E+ R+ +
Sbjct: 298 ERKRERQRERERERERNRKRERERERERERERQ-----RETERDREKERERKRKRQTEMD 352
Query: 101 PTRTVEVDSKAAEIGKKGEDKTTQKDTTDS-ESELKQGKKDSKKGKDIEKGKEEKLDAKK 159
R + + ++ ++ ++D + E E ++ +D + K+ E+ E+ D ++
Sbjct: 353 RERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQR 412
Query: 160 DSKKGK-----KDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSAT 204
+++K + +++E+G++ E E +KG + ++ + + + + +T
Sbjct: 413 ETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRST 462
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.298 0.120 0.313
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,664,910
Number of Sequences: 37866
Number of extensions: 727865
Number of successful extensions: 23452
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 820
Number of HSP's successfully gapped in prelim test: 887
Number of HSP's that attempted gapping in prelim test: 4414
Number of HSP's gapped (non-prelim): 8424
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 44 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.