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Search of human proteins with 45237193
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo
sapiens]
(314 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo ... 627 e-180
gi|208609988 solute carrier family 25, member 44 isoform 2 [Homo... 292 3e-79
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 104 9e-23
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 104 9e-23
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 104 1e-22
gi|13899342 solute carrier [Homo sapiens] 100 2e-21
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 93 3e-19
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 93 3e-19
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 93 3e-19
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 93 3e-19
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 93 3e-19
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 93 3e-19
gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens] 89 5e-18
gi|7706306 solute carrier family 25, member 39 isoform b [Homo s... 88 9e-18
gi|219555665 solute carrier family 25, member 39 isoform a [Homo... 88 9e-18
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 88 9e-18
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 86 3e-17
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 86 3e-17
gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 85 7e-17
gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 78 9e-15
gi|115430257 solute carrier family 25, member 26 [Homo sapiens] 75 8e-14
gi|149274643 solute carrier family 25, member 28 [Homo sapiens] 75 8e-14
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 75 1e-13
gi|13994341 solute carrier family 25 member 2 [Homo sapiens] 74 1e-13
gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens] 74 2e-13
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 74 2e-13
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 74 2e-13
gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 74 2e-13
gi|46094065 mitochondrial carrier family protein [Homo sapiens] 73 3e-13
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 72 6e-13
>gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo
sapiens]
Length = 314
Score = 627 bits (1616), Expect = e-180
Identities = 314/314 (100%), Positives = 314/314 (100%)
Query: 1 MEDKRNIQIIEWEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDA 60
MEDKRNIQIIEWEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDA
Sbjct: 1 MEDKRNIQIIEWEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDA 60
Query: 61 FIKILRADGITGLYRGFLVNTFTLISGQCYVTTYELTRKFVADYSQSNTVKSLVAGGSAS 120
FIKILRADGITGLYRGFLVNTFTLISGQCYVTTYELTRKFVADYSQSNTVKSLVAGGSAS
Sbjct: 61 FIKILRADGITGLYRGFLVNTFTLISGQCYVTTYELTRKFVADYSQSNTVKSLVAGGSAS 120
Query: 121 LVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLR 180
LVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLR
Sbjct: 121 LVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLR 180
Query: 181 GFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILT 240
GFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILT
Sbjct: 181 GFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILT 240
Query: 241 NPMDVIRTRVQVEGKNSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 300
NPMDVIRTRVQVEGKNSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK
Sbjct: 241 NPMDVIRTRVQVEGKNSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 300
Query: 301 KLSLRPELVDSRHW 314
KLSLRPELVDSRHW
Sbjct: 301 KLSLRPELVDSRHW 314
>gi|208609988 solute carrier family 25, member 44 isoform 2 [Homo
sapiens]
Length = 205
Score = 292 bits (747), Expect = 3e-79
Identities = 145/157 (92%), Positives = 148/157 (94%)
Query: 158 QGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPK 217
+G + T D +ILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPK
Sbjct: 49 KGKSLYHGTFDAFIKILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPK 108
Query: 218 ECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGKNSIILTFRQLMAEEGPWGLMKG 277
ECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGKNSIILTFRQLMAEEGPWGLMKG
Sbjct: 109 ECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGKNSIILTFRQLMAEEGPWGLMKG 168
Query: 278 LSARIISATPSTIVIVVGYESLKKLSLRPELVDSRHW 314
LSARIISATPSTIVIVVGYESLKKLSLRPELVDSRHW
Sbjct: 169 LSARIISATPSTIVIVVGYESLKKLSLRPELVDSRHW 205
Score = 166 bits (420), Expect = 2e-41
Identities = 94/203 (46%), Positives = 121/203 (59%), Gaps = 25/203 (12%)
Query: 1 MEDKRNIQIIEWEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDA 60
MEDKRNIQIIEWEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDA
Sbjct: 1 MEDKRNIQIIEWEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDA 60
Query: 61 FIKILRADGITGLYRGFLVNTFTLISGQC----YVTTYELTRKFVADYSQSNTVKSLVAG 116
FIKIL+ADG+ G YRG++ + T I + Y ++ + V V+G
Sbjct: 61 FIKILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSG 120
Query: 117 GSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQA 176
A+ A +T P+DV+ + ++ K + F RQ++
Sbjct: 121 PLAAATASILTNPMDVIRTRVQVEGKNSIILTF---------------------RQLMAE 159
Query: 177 DGLRGFYRGYVASLLTYIPNSAV 199
+G G +G A +++ P++ V
Sbjct: 160 EGPWGLMKGLSARIISATPSTIV 182
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 104 bits (260), Expect = 9e-23
Identities = 85/283 (30%), Positives = 131/283 (46%), Gaps = 37/283 (13%)
Query: 34 SVYPFTLIRTRLQVQK------GKSLYHGTFDAFIKILRADGITGLYRGFLVNTFTLISG 87
+VYP L++TR+Q Q+ G+ +Y +FD F K+LR +G GLYRG L +
Sbjct: 345 AVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPE 404
Query: 88 QCY-VTTYELTR-KFVADYSQSNTVKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEK 145
+ +T + R KF+ ++AGG A T P+++V
Sbjct: 405 KAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKI---------- 454
Query: 146 MGRFQVRGN-PEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFY 204
R QV G G V A +D+ G G Y+G A L IP SA+++P Y
Sbjct: 455 --RLQVAGEITTGPRVSALSVVRDL--------GFFGIYKGAKACFLRDIPFSAIYFPCY 504
Query: 205 HFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGK------NSI 258
+ + P + A G +A A+ L P DVI+TR+QV + + +
Sbjct: 505 AHVKASFANEDGQVSPGSLLLA--GAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGV 562
Query: 259 ILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 301
I FR+++ EEGP L KG AR+ ++P V ++ YE L++
Sbjct: 563 IDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 605
Score = 31.2 bits (69), Expect = 1.2
Identities = 19/74 (25%), Positives = 37/74 (50%), Gaps = 12/74 (16%)
Query: 229 GPLAAATASILTNPMDVIRTRVQVEG-----------KNSIILTFRQLMAEEGPWGLMKG 277
G +A A + P+D+++TR+Q + KNS F++++ EG +GL +G
Sbjct: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFD-CFKKVLRYEGFFGLYRG 393
Query: 278 LSARIISATPSTIV 291
L +++ P +
Sbjct: 394 LLPQLLGVAPEKAI 407
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 104 bits (260), Expect = 9e-23
Identities = 85/283 (30%), Positives = 131/283 (46%), Gaps = 37/283 (13%)
Query: 34 SVYPFTLIRTRLQVQK------GKSLYHGTFDAFIKILRADGITGLYRGFLVNTFTLISG 87
+VYP L++TR+Q Q+ G+ +Y +FD F K+LR +G GLYRG L +
Sbjct: 346 AVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPE 405
Query: 88 QCY-VTTYELTR-KFVADYSQSNTVKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEK 145
+ +T + R KF+ ++AGG A T P+++V
Sbjct: 406 KAIKLTVNDFVRDKFMHKDGSVPLAAEILAGGCAGGSQVIFTNPLEIVKI---------- 455
Query: 146 MGRFQVRGN-PEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFY 204
R QV G G V A +D+ G G Y+G A L IP SA+++P Y
Sbjct: 456 --RLQVAGEITTGPRVSALSVVRDL--------GFFGIYKGAKACFLRDIPFSAIYFPCY 505
Query: 205 HFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGK------NSI 258
+ + P + A G +A A+ L P DVI+TR+QV + + +
Sbjct: 506 AHVKASFANEDGQVSPGSLLLA--GAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGV 563
Query: 259 ILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 301
I FR+++ EEGP L KG AR+ ++P V ++ YE L++
Sbjct: 564 IDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQR 606
Score = 31.2 bits (69), Expect = 1.2
Identities = 19/74 (25%), Positives = 37/74 (50%), Gaps = 12/74 (16%)
Query: 229 GPLAAATASILTNPMDVIRTRVQVEG-----------KNSIILTFRQLMAEEGPWGLMKG 277
G +A A + P+D+++TR+Q + KNS F++++ EG +GL +G
Sbjct: 336 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFD-CFKKVLRYEGFFGLYRG 394
Query: 278 LSARIISATPSTIV 291
L +++ P +
Sbjct: 395 LLPQLLGVAPEKAI 408
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 104 bits (259), Expect = 1e-22
Identities = 85/285 (29%), Positives = 131/285 (45%), Gaps = 41/285 (14%)
Query: 34 SVYPFTLIRTRLQVQKGKS------LYHGTFDAFIKILRADGITGLYRGFLVNTFTLISG 87
+VYP L++TR+Q Q+G +Y +FD F K+LR +G GLYRG + +
Sbjct: 343 AVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPE 402
Query: 88 QCY-VTTYELTR-KFVADYSQSNTVKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEK 145
+ +T + R KF ++AGG A T P+++V
Sbjct: 403 KAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKI---------- 452
Query: 146 MGRFQVRGN-PEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFY 204
R QV G G V A +D+ G+ G Y+G A L IP SA+++P Y
Sbjct: 453 --RLQVAGEITTGPRVSALNVLRDL--------GIFGLYKGAKACFLRDIPFSAIYFPVY 502
Query: 205 HFYAEQLSYLCPKECPHI--VFQAVSGPLAAATASILTNPMDVIRTRVQVEGK------N 256
L E H+ + +G +A A+ L P DVI+TR+QV + +
Sbjct: 503 ----AHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYS 558
Query: 257 SIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 301
+I FR+++ EEGP KG +AR+ ++P V +V YE L++
Sbjct: 559 GVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQR 603
Score = 33.5 bits (75), Expect = 0.25
Identities = 19/73 (26%), Positives = 38/73 (52%), Gaps = 10/73 (13%)
Query: 229 GPLAAATASILTNPMDVIRTRVQVE-GKNSII---------LTFRQLMAEEGPWGLMKGL 278
G +A A + P+D+++TR+Q + G S++ F++++ EG +GL +GL
Sbjct: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392
Query: 279 SARIISATPSTIV 291
++I P +
Sbjct: 393 IPQLIGVAPEKAI 405
>gi|13899342 solute carrier [Homo sapiens]
Length = 315
Score = 100 bits (249), Expect = 2e-21
Identities = 77/270 (28%), Positives = 123/270 (45%), Gaps = 19/270 (7%)
Query: 35 VYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGITGLYRGFLVNTFTLISGQCYVTTY 94
V+P L +TRLQ Q GK++Y G D +K RA+G G+YRG VN TL++ + +
Sbjct: 26 VFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRGAAVN-LTLVTPEKAIKLA 84
Query: 95 E---LTRKFVADYSQSNTVKSLVAGGSASLVAQSITVPIDVV------SQHLMMQRKGEK 145
R + D Q N ++AG A + +T P++++ + L + +G
Sbjct: 85 ANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSA 144
Query: 146 MGRFQVRGNPEGQGVVAFGQTKDIIR-QILQADGLRGFYRGYVASLLTYIPNSAVWWPFY 204
R G + +I ++L+ GL G YRG A+LL IP S +++P +
Sbjct: 145 SAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLF 204
Query: 205 HFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGK-------NS 257
L + VSG +A + A++ P+DV++TR+Q K +
Sbjct: 205 -ANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSG 263
Query: 258 IILTFRQLMAEEGPWGLMKGLSARIISATP 287
I R+L +EGP MKG R + P
Sbjct: 264 ITDCARKLWIQEGPSAFMKGAGCRALVIAP 293
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 92.8 bits (229), Expect = 3e-19
Identities = 71/299 (23%), Positives = 129/299 (43%), Gaps = 34/299 (11%)
Query: 12 WEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGIT 71
W HL V G + R P ++ +QV +S G F +++R G
Sbjct: 187 WRHL------VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 240
Query: 72 GLYRGFLVNTFTLISGQCY-VTTYELTRKFVADYSQSNTV-KSLVAGGSASLVAQSITVP 129
L+RG +N + YE ++ V ++ + + LVAG A +AQS P
Sbjct: 241 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 300
Query: 130 IDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVAS 189
++V+ + +++ G+ G D R+IL +G+ FY+GYV +
Sbjct: 301 MEVLKTRMALRKTGQYSGML------------------DCARRILAREGVAAFYKGYVPN 342
Query: 190 LLTYIPNSAVWWPFYHFY--AEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIR 247
+L IP + + Y A Y P + G +++ + + P+ ++R
Sbjct: 343 MLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVR 402
Query: 248 TRVQ----VEGKNSIILT--FRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 300
TR+Q +EG + ++ F+ ++ EG +GL +GL+ + P+ + V YE+LK
Sbjct: 403 TRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Score = 59.3 bits (142), Expect = 4e-09
Identities = 56/206 (27%), Positives = 95/206 (46%), Gaps = 26/206 (12%)
Query: 111 KSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDII 170
+ LVAGG A V+++ T P+D + ++MQ + + G
Sbjct: 188 RHLVAGGGAGAVSRTCTAPLDRLK--VLMQVHASRSNNMGIVGG---------------F 230
Query: 171 RQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLC--PKECPHIVFQAVS 228
Q+++ G R +RG ++L P SA+ + Y EQ+ L +E I + V+
Sbjct: 231 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAY----EQIKRLVGSDQETLRIHERLVA 286
Query: 229 GPLAAATASILTNPMDVIRTRVQVE--GKNSIILTF-RQLMAEEGPWGLMKGLSARIISA 285
G LA A A PM+V++TR+ + G+ S +L R+++A EG KG ++
Sbjct: 287 GSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGI 346
Query: 286 TPSTIVIVVGYESLKKLSLRPELVDS 311
P + + YE+LK L+ V+S
Sbjct: 347 IPYAGIDLAVYETLKNAWLQHYAVNS 372
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 92.8 bits (229), Expect = 3e-19
Identities = 71/299 (23%), Positives = 129/299 (43%), Gaps = 34/299 (11%)
Query: 12 WEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGIT 71
W HL V G + R P ++ +QV +S G F +++R G
Sbjct: 221 WRHL------VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 274
Query: 72 GLYRGFLVNTFTLISGQCY-VTTYELTRKFVADYSQSNTV-KSLVAGGSASLVAQSITVP 129
L+RG +N + YE ++ V ++ + + LVAG A +AQS P
Sbjct: 275 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 334
Query: 130 IDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVAS 189
++V+ + +++ G+ G D R+IL +G+ FY+GYV +
Sbjct: 335 MEVLKTRMALRKTGQYSGML------------------DCARRILAREGVAAFYKGYVPN 376
Query: 190 LLTYIPNSAVWWPFYHFY--AEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIR 247
+L IP + + Y A Y P + G +++ + + P+ ++R
Sbjct: 377 MLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVR 436
Query: 248 TRVQ----VEGKNSIILT--FRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 300
TR+Q +EG + ++ F+ ++ EG +GL +GL+ + P+ + V YE+LK
Sbjct: 437 TRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Score = 59.3 bits (142), Expect = 4e-09
Identities = 56/206 (27%), Positives = 95/206 (46%), Gaps = 26/206 (12%)
Query: 111 KSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDII 170
+ LVAGG A V+++ T P+D + ++MQ + + G
Sbjct: 222 RHLVAGGGAGAVSRTCTAPLDRLK--VLMQVHASRSNNMGIVGG---------------F 264
Query: 171 RQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLC--PKECPHIVFQAVS 228
Q+++ G R +RG ++L P SA+ + Y EQ+ L +E I + V+
Sbjct: 265 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAY----EQIKRLVGSDQETLRIHERLVA 320
Query: 229 GPLAAATASILTNPMDVIRTRVQVE--GKNSIILTF-RQLMAEEGPWGLMKGLSARIISA 285
G LA A A PM+V++TR+ + G+ S +L R+++A EG KG ++
Sbjct: 321 GSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGI 380
Query: 286 TPSTIVIVVGYESLKKLSLRPELVDS 311
P + + YE+LK L+ V+S
Sbjct: 381 IPYAGIDLAVYETLKNAWLQHYAVNS 406
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 92.8 bits (229), Expect = 3e-19
Identities = 71/299 (23%), Positives = 129/299 (43%), Gaps = 34/299 (11%)
Query: 12 WEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGIT 71
W HL V G + R P ++ +QV +S G F +++R G
Sbjct: 207 WRHL------VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 260
Query: 72 GLYRGFLVNTFTLISGQCY-VTTYELTRKFVADYSQSNTV-KSLVAGGSASLVAQSITVP 129
L+RG +N + YE ++ V ++ + + LVAG A +AQS P
Sbjct: 261 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 320
Query: 130 IDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVAS 189
++V+ + +++ G+ G D R+IL +G+ FY+GYV +
Sbjct: 321 MEVLKTRMALRKTGQYSGML------------------DCARRILAREGVAAFYKGYVPN 362
Query: 190 LLTYIPNSAVWWPFYHFY--AEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIR 247
+L IP + + Y A Y P + G +++ + + P+ ++R
Sbjct: 363 MLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVR 422
Query: 248 TRVQ----VEGKNSIILT--FRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 300
TR+Q +EG + ++ F+ ++ EG +GL +GL+ + P+ + V YE+LK
Sbjct: 423 TRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 481
Score = 59.3 bits (142), Expect = 4e-09
Identities = 56/206 (27%), Positives = 95/206 (46%), Gaps = 26/206 (12%)
Query: 111 KSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDII 170
+ LVAGG A V+++ T P+D + ++MQ + + G
Sbjct: 208 RHLVAGGGAGAVSRTCTAPLDRLK--VLMQVHASRSNNMGIVGG---------------F 250
Query: 171 RQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLC--PKECPHIVFQAVS 228
Q+++ G R +RG ++L P SA+ + Y EQ+ L +E I + V+
Sbjct: 251 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAY----EQIKRLVGSDQETLRIHERLVA 306
Query: 229 GPLAAATASILTNPMDVIRTRVQVE--GKNSIILTF-RQLMAEEGPWGLMKGLSARIISA 285
G LA A A PM+V++TR+ + G+ S +L R+++A EG KG ++
Sbjct: 307 GSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGI 366
Query: 286 TPSTIVIVVGYESLKKLSLRPELVDS 311
P + + YE+LK L+ V+S
Sbjct: 367 IPYAGIDLAVYETLKNAWLQHYAVNS 392
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 92.8 bits (229), Expect = 3e-19
Identities = 71/299 (23%), Positives = 129/299 (43%), Gaps = 34/299 (11%)
Query: 12 WEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGIT 71
W HL V G + R P ++ +QV +S G F +++R G
Sbjct: 187 WRHL------VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 240
Query: 72 GLYRGFLVNTFTLISGQCY-VTTYELTRKFVADYSQSNTV-KSLVAGGSASLVAQSITVP 129
L+RG +N + YE ++ V ++ + + LVAG A +AQS P
Sbjct: 241 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 300
Query: 130 IDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVAS 189
++V+ + +++ G+ G D R+IL +G+ FY+GYV +
Sbjct: 301 MEVLKTRMALRKTGQYSGML------------------DCARRILAREGVAAFYKGYVPN 342
Query: 190 LLTYIPNSAVWWPFYHFY--AEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIR 247
+L IP + + Y A Y P + G +++ + + P+ ++R
Sbjct: 343 MLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVR 402
Query: 248 TRVQ----VEGKNSIILT--FRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 300
TR+Q +EG + ++ F+ ++ EG +GL +GL+ + P+ + V YE+LK
Sbjct: 403 TRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Score = 59.3 bits (142), Expect = 4e-09
Identities = 56/206 (27%), Positives = 95/206 (46%), Gaps = 26/206 (12%)
Query: 111 KSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDII 170
+ LVAGG A V+++ T P+D + ++MQ + + G
Sbjct: 188 RHLVAGGGAGAVSRTCTAPLDRLK--VLMQVHASRSNNMGIVGG---------------F 230
Query: 171 RQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLC--PKECPHIVFQAVS 228
Q+++ G R +RG ++L P SA+ + Y EQ+ L +E I + V+
Sbjct: 231 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAY----EQIKRLVGSDQETLRIHERLVA 286
Query: 229 GPLAAATASILTNPMDVIRTRVQVE--GKNSIILTF-RQLMAEEGPWGLMKGLSARIISA 285
G LA A A PM+V++TR+ + G+ S +L R+++A EG KG ++
Sbjct: 287 GSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGI 346
Query: 286 TPSTIVIVVGYESLKKLSLRPELVDS 311
P + + YE+LK L+ V+S
Sbjct: 347 IPYAGIDLAVYETLKNAWLQHYAVNS 372
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 92.8 bits (229), Expect = 3e-19
Identities = 71/299 (23%), Positives = 129/299 (43%), Gaps = 34/299 (11%)
Query: 12 WEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGIT 71
W HL V G + R P ++ +QV +S G F +++R G
Sbjct: 84 WRHL------VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 137
Query: 72 GLYRGFLVNTFTLISGQCY-VTTYELTRKFVADYSQSNTV-KSLVAGGSASLVAQSITVP 129
L+RG +N + YE ++ V ++ + + LVAG A +AQS P
Sbjct: 138 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 197
Query: 130 IDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVAS 189
++V+ + +++ G+ G D R+IL +G+ FY+GYV +
Sbjct: 198 MEVLKTRMALRKTGQYSGML------------------DCARRILAREGVAAFYKGYVPN 239
Query: 190 LLTYIPNSAVWWPFYHFY--AEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIR 247
+L IP + + Y A Y P + G +++ + + P+ ++R
Sbjct: 240 MLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVR 299
Query: 248 TRVQ----VEGKNSIILT--FRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 300
TR+Q +EG + ++ F+ ++ EG +GL +GL+ + P+ + V YE+LK
Sbjct: 300 TRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 358
Score = 59.3 bits (142), Expect = 4e-09
Identities = 56/206 (27%), Positives = 95/206 (46%), Gaps = 26/206 (12%)
Query: 111 KSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDII 170
+ LVAGG A V+++ T P+D + ++MQ + + G
Sbjct: 85 RHLVAGGGAGAVSRTCTAPLDRLK--VLMQVHASRSNNMGIVGG---------------F 127
Query: 171 RQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLC--PKECPHIVFQAVS 228
Q+++ G R +RG ++L P SA+ + Y EQ+ L +E I + V+
Sbjct: 128 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAY----EQIKRLVGSDQETLRIHERLVA 183
Query: 229 GPLAAATASILTNPMDVIRTRVQVE--GKNSIILTF-RQLMAEEGPWGLMKGLSARIISA 285
G LA A A PM+V++TR+ + G+ S +L R+++A EG KG ++
Sbjct: 184 GSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGI 243
Query: 286 TPSTIVIVVGYESLKKLSLRPELVDS 311
P + + YE+LK L+ V+S
Sbjct: 244 IPYAGIDLAVYETLKNAWLQHYAVNS 269
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 92.8 bits (229), Expect = 3e-19
Identities = 71/299 (23%), Positives = 129/299 (43%), Gaps = 34/299 (11%)
Query: 12 WEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGIT 71
W HL V G + R P ++ +QV +S G F +++R G
Sbjct: 221 WRHL------VAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGAR 274
Query: 72 GLYRGFLVNTFTLISGQCY-VTTYELTRKFVADYSQSNTV-KSLVAGGSASLVAQSITVP 129
L+RG +N + YE ++ V ++ + + LVAG A +AQS P
Sbjct: 275 SLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYP 334
Query: 130 IDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVAS 189
++V+ + +++ G+ G D R+IL +G+ FY+GYV +
Sbjct: 335 MEVLKTRMALRKTGQYSGML------------------DCARRILAREGVAAFYKGYVPN 376
Query: 190 LLTYIPNSAVWWPFYHFY--AEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIR 247
+L IP + + Y A Y P + G +++ + + P+ ++R
Sbjct: 377 MLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVR 436
Query: 248 TRVQ----VEGKNSIILT--FRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 300
TR+Q +EG + ++ F+ ++ EG +GL +GL+ + P+ + V YE+LK
Sbjct: 437 TRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Score = 59.3 bits (142), Expect = 4e-09
Identities = 56/206 (27%), Positives = 95/206 (46%), Gaps = 26/206 (12%)
Query: 111 KSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDII 170
+ LVAGG A V+++ T P+D + ++MQ + + G
Sbjct: 222 RHLVAGGGAGAVSRTCTAPLDRLK--VLMQVHASRSNNMGIVGG---------------F 264
Query: 171 RQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLC--PKECPHIVFQAVS 228
Q+++ G R +RG ++L P SA+ + Y EQ+ L +E I + V+
Sbjct: 265 TQMIREGGARSLWRGNGINVLKIAPESAIKFMAY----EQIKRLVGSDQETLRIHERLVA 320
Query: 229 GPLAAATASILTNPMDVIRTRVQVE--GKNSIILTF-RQLMAEEGPWGLMKGLSARIISA 285
G LA A A PM+V++TR+ + G+ S +L R+++A EG KG ++
Sbjct: 321 GSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGI 380
Query: 286 TPSTIVIVVGYESLKKLSLRPELVDS 311
P + + YE+LK L+ V+S
Sbjct: 381 IPYAGIDLAVYETLKNAWLQHYAVNS 406
>gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens]
Length = 323
Score = 89.0 bits (219), Expect = 5e-18
Identities = 74/274 (27%), Positives = 129/274 (47%), Gaps = 23/274 (8%)
Query: 35 VYPFTLIRTRLQVQK-GKSLYHGTFDAFIKILRADGITGLYRGFLVNTFTLISGQCYVTT 93
V+P L +TRLQ Q+ G+ +Y D IK +R++G G+YRG VN TL++ + +
Sbjct: 26 VFPIDLAKTRLQNQQNGQRVYTSMSDCLIKTVRSEGYFGMYRGAAVN-LTLVTPEKAIKL 84
Query: 94 YE---LTRKFVADYSQSNTVKSLVAGGSASLVAQSITVPIDVVSQHLM------MQRK-G 143
+ D + +K ++AG A +T P++++ L QRK
Sbjct: 85 AANDFFRHQLSKDGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKIL 144
Query: 144 EKMGRFQVRG--NPEGQGVVAFGQT-KDIIRQILQADGLRGFYRGYVASLLTYIPNSAVW 200
G+ +G P + A T + R +L++ G+ G Y+G A+LL +P S V+
Sbjct: 145 AAQGQLSAQGGAQPSVEAPAAPRPTATQLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVY 204
Query: 201 WPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQ-------VE 253
+P + QL +E ++G +A + A++ NP DV++TR+Q +
Sbjct: 205 FPLF-ANLNQLGRPASEEKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLQRGVNED 263
Query: 254 GKNSIILTFRQLMAEEGPWGLMKGLSARIISATP 287
+ I+ R+++ EGP +KG R + P
Sbjct: 264 TYSGILDCARKILRHEGPSAFLKGAYCRALVIAP 297
>gi|7706306 solute carrier family 25, member 39 isoform b [Homo
sapiens]
Length = 351
Score = 88.2 bits (217), Expect = 9e-18
Identities = 67/258 (25%), Positives = 114/258 (44%), Gaps = 33/258 (12%)
Query: 54 YHGTFDAFIKILRADGITGLYRGFLVN-TFTLISGQCYVTTYELTRKFVADYS-QSNTVK 111
+ GT DAF+KI+R +G L+ G T+ + Y T Y+ + F+ + S+
Sbjct: 96 FTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYA 155
Query: 112 SLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIR 171
+VAG A L ++ P++++ L Q V++ + +R
Sbjct: 156 PMVAGALARLGTVTVISPLELMRTKLQAQH-------------------VSYRELGACVR 196
Query: 172 QILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPL 231
+ G R + G+ + L +P SA++W Y L+ PK+ + V+G +
Sbjct: 197 TAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGI 256
Query: 232 AAATASILTNPMDVIRTRVQVE------------GKNSIILTFRQLMAEEGPWGLMKGLS 279
+ A++LT P DV++T+ QV +S L R++ AE G GL G
Sbjct: 257 SGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFL 316
Query: 280 ARIISATPSTIVIVVGYE 297
RII A PS +++ YE
Sbjct: 317 PRIIKAAPSCAIMISTYE 334
>gi|219555665 solute carrier family 25, member 39 isoform a [Homo
sapiens]
Length = 359
Score = 88.2 bits (217), Expect = 9e-18
Identities = 67/258 (25%), Positives = 114/258 (44%), Gaps = 33/258 (12%)
Query: 54 YHGTFDAFIKILRADGITGLYRGFLVN-TFTLISGQCYVTTYELTRKFVADYS-QSNTVK 111
+ GT DAF+KI+R +G L+ G T+ + Y T Y+ + F+ + S+
Sbjct: 104 FTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYA 163
Query: 112 SLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIR 171
+VAG A L ++ P++++ L Q V++ + +R
Sbjct: 164 PMVAGALARLGTVTVISPLELMRTKLQAQH-------------------VSYRELGACVR 204
Query: 172 QILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPL 231
+ G R + G+ + L +P SA++W Y L+ PK+ + V+G +
Sbjct: 205 TAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGI 264
Query: 232 AAATASILTNPMDVIRTRVQVE------------GKNSIILTFRQLMAEEGPWGLMKGLS 279
+ A++LT P DV++T+ QV +S L R++ AE G GL G
Sbjct: 265 SGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFL 324
Query: 280 ARIISATPSTIVIVVGYE 297
RII A PS +++ YE
Sbjct: 325 PRIIKAAPSCAIMISTYE 342
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 88.2 bits (217), Expect = 9e-18
Identities = 70/295 (23%), Positives = 133/295 (45%), Gaps = 32/295 (10%)
Query: 19 KFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGITGLYRGFL 78
K V G + R P ++ +QV K+ ++ GI L+RG
Sbjct: 187 KQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNG 246
Query: 79 VNTFTLI--SGQCYVTTYELTRKFVADYSQSNTVKSLVAGGSASLVAQSITVPIDVVSQH 136
+N + S ++ ++ R + + + VAG A AQ+I P++V+
Sbjct: 247 INVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKTR 306
Query: 137 LMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIP- 195
L ++R G+ G D R+IL+ +G R FYRGY+ ++L IP
Sbjct: 307 LTLRRTGQYKGLL------------------DCARRILEREGPRAFYRGYLPNVLGIIPY 348
Query: 196 ---NSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQ- 251
+ AV+ +++ +Q S+ P I+ G +++ I + P+ ++RTR+Q
Sbjct: 349 AGIDLAVYETLKNWWLQQYSH--DSADPGILVLLACGTISSTCGQIASYPLALVRTRMQA 406
Query: 252 ---VEG--KNSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 301
+EG + S++ R ++++EG GL +G++ + P+ + V YE++K+
Sbjct: 407 QASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQ 461
Score = 67.0 bits (162), Expect = 2e-11
Identities = 55/206 (26%), Positives = 95/206 (46%), Gaps = 26/206 (12%)
Query: 111 KSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDII 170
K LVAG A V+++ T P+D + + MQ K R + G +
Sbjct: 187 KQLVAGAVAGAVSRTGTAPLDRLK--VFMQVHASKTNRLNILGG---------------L 229
Query: 171 RQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQL--SYLCPKECPHIVFQAVS 228
R ++ G+R +RG ++L P SA+ + Y EQ+ + L +E H+ + V+
Sbjct: 230 RSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAY----EQIKRAILGQQETLHVQERFVA 285
Query: 229 GPLAAATASILTNPMDVIRTRVQVEGKNS---IILTFRQLMAEEGPWGLMKGLSARIISA 285
G LA ATA + PM+V++TR+ + ++ R+++ EGP +G ++
Sbjct: 286 GSLAGATAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGI 345
Query: 286 TPSTIVIVVGYESLKKLSLRPELVDS 311
P + + YE+LK L+ DS
Sbjct: 346 IPYAGIDLAVYETLKNWWLQQYSHDS 371
Score = 55.1 bits (131), Expect = 8e-08
Identities = 45/198 (22%), Positives = 83/198 (41%), Gaps = 22/198 (11%)
Query: 13 EHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGITG 72
E L ++ +V G + +YP +++TRL +++ Y G D +IL +G
Sbjct: 275 ETLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRR-TGQYKGLLDCARRILEREGPRA 333
Query: 73 LYRGFLVNTFTLIS-GQCYVTTYELTR-----KFVADYSQSNTVKSLVAGGSASLVAQSI 126
YRG+L N +I + YE + ++ D + + L G +S Q
Sbjct: 334 FYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIA 393
Query: 127 TVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGY 186
+ P+ +V + Q + G P+ + ++R IL +G+RG YRG
Sbjct: 394 SYPLALVRTRMQAQA--------SIEGGPQLSML-------GLLRHILSQEGMRGLYRGI 438
Query: 187 VASLLTYIPNSAVWWPFY 204
+ + IP ++ + Y
Sbjct: 439 APNFMKVIPAVSISYVVY 456
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 86.3 bits (212), Expect = 3e-17
Identities = 65/280 (23%), Positives = 126/280 (45%), Gaps = 28/280 (10%)
Query: 32 RVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGITGLYRGFLVNTFTLISGQCY- 90
R S P ++ +QV KS F F ++++ GI L+RG N +
Sbjct: 209 RTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAPETAVK 268
Query: 91 VTTYELTRKFVADYSQS-NTVKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRF 149
YE +K + + Q T + ++G A AQ+ P++V+ L + + G+ G +
Sbjct: 269 FWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIY 328
Query: 150 QVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAE 209
D ++IL+ +GL FY+GYV +LL IP + + Y
Sbjct: 329 ------------------DCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKS 370
Query: 210 QLSYLCPKEC--PHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEG------KNSIILT 261
K+ P ++ G L++ + + P+ ++RTR+Q + + +++
Sbjct: 371 YWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGL 430
Query: 262 FRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 301
FR+++++EG GL +G++ + P+ + V YE++K+
Sbjct: 431 FRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 470
Score = 62.8 bits (151), Expect = 4e-10
Identities = 55/197 (27%), Positives = 93/197 (47%), Gaps = 30/197 (15%)
Query: 111 KSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDII 170
+ L+AGG A V+++ T P+D + +MMQ G K + + G
Sbjct: 196 RQLLAGGIAGAVSRTSTAPLDRLK--IMMQVHGSKSDKMNIFGG---------------F 238
Query: 171 RQILQADGLRGFYRGYVASLLTYIPNSAV-WWPFYHFYAEQLSYLCPKECPHI-VFQA-V 227
RQ+++ G+R +RG +++ P +AV +W + EQ L +E I F+ +
Sbjct: 239 RQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAY-----EQYKKLLTEEGQKIGTFERFI 293
Query: 228 SGPLAAATASILTNPMDVIRTRVQVEGK----NSIILTFRQLMAEEGPWGLMKGLSARII 283
SG +A ATA PM+V++TR+ V GK + I ++++ EG KG ++
Sbjct: 294 SGSMAGATAQTFIYPMEVMKTRLAV-GKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLL 352
Query: 284 SATPSTIVIVVGYESLK 300
P + + YE LK
Sbjct: 353 GIIPYAGIDLAVYELLK 369
Score = 45.1 bits (105), Expect = 8e-05
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 225 QAVSGPLAAATASILTNPMDVIRTRVQVEGKNS----IILTFRQLMAEEGPWGLMKGLSA 280
Q ++G +A A + T P+D ++ +QV G S I FRQ++ E G L +G
Sbjct: 197 QLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGT 256
Query: 281 RIISATPSTIVIVVGYESLKKL 302
+I P T V YE KKL
Sbjct: 257 NVIKIAPETAVKFWAYEQYKKL 278
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 86.3 bits (212), Expect = 3e-17
Identities = 65/280 (23%), Positives = 126/280 (45%), Gaps = 28/280 (10%)
Query: 32 RVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGITGLYRGFLVNTFTLISGQCY- 90
R S P ++ +QV KS F F ++++ GI L+RG N +
Sbjct: 190 RTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAPETAVK 249
Query: 91 VTTYELTRKFVADYSQS-NTVKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRF 149
YE +K + + Q T + ++G A AQ+ P++V+ L + + G+ G +
Sbjct: 250 FWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIY 309
Query: 150 QVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAE 209
D ++IL+ +GL FY+GYV +LL IP + + Y
Sbjct: 310 ------------------DCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKS 351
Query: 210 QLSYLCPKEC--PHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEG------KNSIILT 261
K+ P ++ G L++ + + P+ ++RTR+Q + + +++
Sbjct: 352 YWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGL 411
Query: 262 FRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 301
FR+++++EG GL +G++ + P+ + V YE++K+
Sbjct: 412 FRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 451
Score = 62.8 bits (151), Expect = 4e-10
Identities = 55/197 (27%), Positives = 93/197 (47%), Gaps = 30/197 (15%)
Query: 111 KSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDII 170
+ L+AGG A V+++ T P+D + +MMQ G K + + G
Sbjct: 177 RQLLAGGIAGAVSRTSTAPLDRLK--IMMQVHGSKSDKMNIFGG---------------F 219
Query: 171 RQILQADGLRGFYRGYVASLLTYIPNSAV-WWPFYHFYAEQLSYLCPKECPHI-VFQA-V 227
RQ+++ G+R +RG +++ P +AV +W + EQ L +E I F+ +
Sbjct: 220 RQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAY-----EQYKKLLTEEGQKIGTFERFI 274
Query: 228 SGPLAAATASILTNPMDVIRTRVQVEGK----NSIILTFRQLMAEEGPWGLMKGLSARII 283
SG +A ATA PM+V++TR+ V GK + I ++++ EG KG ++
Sbjct: 275 SGSMAGATAQTFIYPMEVMKTRLAV-GKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLL 333
Query: 284 SATPSTIVIVVGYESLK 300
P + + YE LK
Sbjct: 334 GIIPYAGIDLAVYELLK 350
Score = 45.1 bits (105), Expect = 8e-05
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 225 QAVSGPLAAATASILTNPMDVIRTRVQVEGKNS----IILTFRQLMAEEGPWGLMKGLSA 280
Q ++G +A A + T P+D ++ +QV G S I FRQ++ E G L +G
Sbjct: 178 QLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGT 237
Query: 281 RIISATPSTIVIVVGYESLKKL 302
+I P T V YE KKL
Sbjct: 238 NVIKIAPETAVKFWAYEQYKKL 259
>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
Length = 338
Score = 85.1 bits (209), Expect = 7e-17
Identities = 82/304 (26%), Positives = 133/304 (43%), Gaps = 45/304 (14%)
Query: 26 AMTMMIRVSV-YPFTLIRTRLQVQKG--KSLYHGTFDAFIKILRADGITGLYRGFLVNTF 82
AM ++ SV YP ++TR+Q K+ Y + A KI+R +G RG VN
Sbjct: 53 AMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRG--VNVM 110
Query: 83 TLISGQC---YVTTYELTRKFVAD--YSQSNT-VKSLVAGGSASLVAQSITVPIDVVSQH 136
+ +G Y YE ++ + D + Q N+ + + +AG A+L+ ++ P +VV Q
Sbjct: 111 IMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQR 170
Query: 137 LMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPN 196
L M N + + ++ IR + + +GL FYR Y L IP
Sbjct: 171 LQMY-------------NSQHRSAIS------CIRTVWRTEGLGAFYRSYTTQLTMNIPF 211
Query: 197 SAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGKN 256
++ + Y F EQ++ P + +SG LA A A+ T P+DV +T + +
Sbjct: 212 QSIHFITYEFLQEQVN---PHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENV 268
Query: 257 SIIL------------TFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKKLSL 304
++ L FR + G G KG+ AR+I PST + YE K
Sbjct: 269 ALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLT 328
Query: 305 RPEL 308
+ +L
Sbjct: 329 KRQL 332
Score = 62.0 bits (149), Expect = 7e-10
Identities = 40/187 (21%), Positives = 82/187 (43%), Gaps = 12/187 (6%)
Query: 22 VFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGITGLYRGFLVN- 80
+ G T++ + P +++ RLQ+ S + + R +G+ YR +
Sbjct: 148 IAGSMATLLHDAVMNPAEVVKQRLQMYN--SQHRSAISCIRTVWRTEGLGAFYRSYTTQL 205
Query: 81 TFTLISGQCYVTTYELTRKFVADYSQSNTVKSLVAGGSASLVAQSITVPIDVVSQHLMMQ 140
T + + TYE ++ V + N +++GG A +A + T P+DV L+
Sbjct: 206 TMNIPFQSIHFITYEFLQEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKT-LLNT 264
Query: 141 RKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPNSAVW 200
++ + + G G + R + Q +GL G+++G A ++ +P++A+
Sbjct: 265 QENVALSLANISGRLSGMA--------NAFRTVYQLNGLAGYFKGIQARVIYQMPSTAIS 316
Query: 201 WPFYHFY 207
W Y F+
Sbjct: 317 WSVYEFF 323
>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
Length = 370
Score = 78.2 bits (191), Expect = 9e-15
Identities = 68/295 (23%), Positives = 125/295 (42%), Gaps = 34/295 (11%)
Query: 19 KFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGITGLYRGFL 78
KF + G + R P + +QV K+ + +++ G L+RG
Sbjct: 94 KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFTNLLGGLQSMVQEGGFRSLWRGNG 153
Query: 79 VNTFTLISGQCY-VTTYELTRKFVADYSQSNTVKS-LVAGGSASLVAQSITVPIDVVSQH 136
+N + + +E + + S + L+AG A ++Q++ P++V+
Sbjct: 154 INVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQERLLAGSLAVAISQTLINPMEVLKTR 213
Query: 137 LMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPN 196
L ++R G+ G D RQILQ +G R YRGY+ ++L IP
Sbjct: 214 LTLRRTGQYKGLL------------------DCARQILQREGTRALYRGYLPNMLGIIPY 255
Query: 197 SAVWWPFYHFYAEQLSYLCPKE-----CPHIVFQAVSGPLAAATASILTNPMDVIRTRVQ 251
+ Y E L K P + S L+ + + P+ ++RTR+Q
Sbjct: 256 ACTDLAVY----EMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQ 311
Query: 252 ----VEGKNSIIL-TFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 301
VEG N + ++++A++G GL +G++ ++ P+ + V YE++KK
Sbjct: 312 AQDTVEGSNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
>gi|115430257 solute carrier family 25, member 26 [Homo sapiens]
Length = 274
Score = 75.1 bits (183), Expect = 8e-14
Identities = 79/297 (26%), Positives = 125/297 (42%), Gaps = 58/297 (19%)
Query: 22 VFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGITGLYRGF---L 78
V GV++ +++ +P I+TRLQ +G + +A G G+Y G
Sbjct: 15 VAGVSVDLIL----FPLDTIKTRLQSPQGFN-------------KAGGFHGIYAGVPSAA 57
Query: 79 VNTFTLISGQCYVTTYELTRKFV-ADYSQSNT-VKSLVAGGSASLVAQSITVPIDVVSQH 136
+ +F + + TYE + F+ AD S T +K ++A + +VA I VP +VV Q
Sbjct: 58 IGSFP--NAAAFFITYEYVKWFLHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVVKQR 115
Query: 137 LMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPN 196
V A +T I IL +G++G YRGY +++L IP
Sbjct: 116 AQ---------------------VSASTRTFQIFSNILYEEGIQGLYRGYKSTVLREIPF 154
Query: 197 SAVWWPFYHFYAEQLSYLCPKECPHIV---FQAVSGPLAAATASILTNPMDVIRTRVQVE 253
S V +P + E L L H+V AV G A A+ +T P+DV +TR+ +
Sbjct: 155 SLVQFPLW----ESLKALWSWRQDHVVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRIMLA 210
Query: 254 GKNSIILTFRQLMAEEGPW------GLMKGLSARIISATPSTIVIVVGYESLKKLSL 304
S L G W GL G+ R+ + + + + Y+ L L
Sbjct: 211 KAGSSTADGNVLSVLHGVWRSQGLAGLFAGVFPRMAAISLGGFIFLGAYDRTHSLLL 267
Score = 30.4 bits (67), Expect = 2.1
Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 11/82 (13%)
Query: 220 PHIVFQAVSGPLAAATASILTNPMDVIRTRVQ-VEGKNSIILTFRQLMAEEGPWGLMKGL 278
P V V+G +A + ++ P+D I+TR+Q +G N G G+ G+
Sbjct: 4 PGFVAALVAGGVAGVSVDLILFPLDTIKTRLQSPQGFNK----------AGGFHGIYAGV 53
Query: 279 SARIISATPSTIVIVVGYESLK 300
+ I + P+ + YE +K
Sbjct: 54 PSAAIGSFPNAAAFFITYEYVK 75
>gi|149274643 solute carrier family 25, member 28 [Homo sapiens]
Length = 364
Score = 75.1 bits (183), Expect = 8e-14
Identities = 74/298 (24%), Positives = 123/298 (41%), Gaps = 39/298 (13%)
Query: 22 VFGVAMTMMIRVSVYPFTLIRTRLQVQKGK--SLYHGTFDAFIKILRADGITGLYRGFLV 79
V G ++ +YP ++TR+Q + + Y +A +I+R +G+ RG V
Sbjct: 77 VAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALWRIIRTEGLWRPMRGLNV 136
Query: 80 N-TFTLISGQCYVTTYELTRKFVADYSQ---SNTVKSLVAGGSASLVAQSITVPIDVVSQ 135
T + Y YE +K ++D ++ + + AG A+L+ + P +VV Q
Sbjct: 137 TATGAGPAHALYFACYEKLKKTLSDVIHPGGNSHIANGAAGCVATLLHDAAMNPAEVVKQ 196
Query: 136 HLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIP 195
R Q+ +P + + D +R + Q +G FYR Y L +P
Sbjct: 197 ------------RMQMYNSP-------YHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVP 237
Query: 196 NSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVE-- 253
A+ + Y F E + P+ + +SG A A A+ T P+DV +T + +
Sbjct: 238 FQAIHFMTYEFLQEHFN---PQRRYNPSSHVLSGACAGAVAAAATTPLDVCKTLLNTQES 294
Query: 254 -GKNSIIL--------TFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKKL 302
NS I FR + G +G+ AR+I PST + YE K L
Sbjct: 295 LALNSHITGHITGMASAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFKYL 352
Score = 30.8 bits (68), Expect = 1.6
Identities = 36/192 (18%), Positives = 76/192 (39%), Gaps = 19/192 (9%)
Query: 113 LVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQ 172
+VAG A ++ + PID V + ++ +P + + + + +
Sbjct: 76 MVAGAVAGILEHCVMYPIDCVKTRMQ-----------SLQPDPAAR----YRNVLEALWR 120
Query: 173 ILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLS-YLCPKECPHIVFQAVSGPL 231
I++ +GL RG + P A+++ Y + LS + P HI +G +
Sbjct: 121 IIRTEGLWRPMRGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGGNSHIA-NGAAGCV 179
Query: 232 AAATASILTNPMDVIRTRVQVEGK--NSIILTFRQLMAEEGPWGLMKGLSARIISATPST 289
A NP +V++ R+Q+ + + R + EG + + ++ P
Sbjct: 180 ATLLHDAAMNPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQ 239
Query: 290 IVIVVGYESLKK 301
+ + YE L++
Sbjct: 240 AIHFMTYEFLQE 251
>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
Length = 301
Score = 74.7 bits (182), Expect = 1e-13
Identities = 72/283 (25%), Positives = 121/283 (42%), Gaps = 36/283 (12%)
Query: 36 YPFTLIRTRLQVQKGK-----SLYHGTFDAFIKILRADGITGLYRGFLVNTF--TLISGQ 88
+P ++ RLQ Q +Y GTFD F K L +GITGLYRG T +
Sbjct: 29 HPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLYRGMAAPIIGVTPMFAV 88
Query: 89 CYVTTYELTRKFVADYSQS--NTVKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKM 146
C+ + L +K + + + + AG + + I P + + L +Q
Sbjct: 89 CFFG-FGLGKKLQQKHPEDVLSYPQLFAAGMLSGVFTTGIMTPGERIKCLLQIQASS--- 144
Query: 147 GRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFY-- 204
G + T D +++ Q G+RG Y+G V +L+ +P S +++ Y
Sbjct: 145 ------------GESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEW 192
Query: 205 --HFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQV--EGK--NSI 258
+ + + + P I+ V+G +A + P DV+++R Q GK N
Sbjct: 193 LKNIFTPEGKRVSELSAPRIL---VAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGF 249
Query: 259 ILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKK 301
R+L+ +EG L KG +A +I A P+ +G+E K
Sbjct: 250 RDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMK 292
Score = 58.5 bits (140), Expect = 7e-09
Identities = 43/178 (24%), Positives = 83/178 (46%), Gaps = 22/178 (12%)
Query: 44 RLQVQKGKSLYHGTFDAFIKILRADGITGLYRGFLVNTFTLI-SGQCYVTTYELTRKFVA 102
++Q G+S Y GT D K+ + GI G+Y+G ++ + + Y TYE +
Sbjct: 139 QIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEWLKNIFT 198
Query: 103 D----YSQSNTVKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQ 158
S+ + + LVAGG A + ++ +P DV+ RFQ P G+
Sbjct: 199 PEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLK------------SRFQTA--PPGK 244
Query: 159 GVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCP 216
F +D++R++++ +G+ Y+G+ A ++ P +A + + + L++ P
Sbjct: 245 YPNGF---RDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFLNWATP 299
Score = 43.5 bits (101), Expect = 2e-04
Identities = 46/199 (23%), Positives = 85/199 (42%), Gaps = 19/199 (9%)
Query: 110 VKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDI 169
+K+L+AGG + + P+D V L Q + G P + T D
Sbjct: 11 LKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPP-------SLPGQPP-----MYSGTFDC 58
Query: 170 IRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSG 229
R+ L +G+ G YRG A ++ P AV + F ++L P++ +G
Sbjct: 59 FRKTLFREGITGLYRGMAAPIIGVTPMFAVCF-FGFGLGKKLQQKHPEDVLSYPQLFAAG 117
Query: 230 PLAAATASILTNPMDVIRTRVQVE---GKNSIILTF---RQLMAEEGPWGLMKGLSARII 283
L+ + + P + I+ +Q++ G++ T ++L E G G+ KG ++
Sbjct: 118 MLSGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLM 177
Query: 284 SATPSTIVIVVGYESLKKL 302
P++ + + YE LK +
Sbjct: 178 RDVPASGMYFMTYEWLKNI 196
Score = 29.3 bits (64), Expect = 4.7
Identities = 17/68 (25%), Positives = 36/68 (52%), Gaps = 5/68 (7%)
Query: 37 PFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGITGLYRGF---LVNTFTLISGQCYVTT 93
P ++++R Q +G D +++R +G+T LY+GF ++ F + C++
Sbjct: 229 PPDVLKSRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFP-ANAACFL-G 286
Query: 94 YELTRKFV 101
+E+ KF+
Sbjct: 287 FEVAMKFL 294
>gi|13994341 solute carrier family 25 member 2 [Homo sapiens]
Length = 301
Score = 74.3 bits (181), Expect = 1e-13
Identities = 71/282 (25%), Positives = 118/282 (41%), Gaps = 27/282 (9%)
Query: 37 PFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGITGLYRG-------FLVNTFTLISGQC 89
PF I+ ++Q LY G D F+K G+ G Y+G ++ L C
Sbjct: 29 PFDTIKVKMQTFP--DLYKGLTDCFLKTYAQVGLRGFYKGTGPALMAYVAENSVLF--MC 84
Query: 90 YVTTYELTRKFVADYSQS--NTVKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMG 147
Y + RK Q+ + +++ AG AS A P ++V L + E G
Sbjct: 85 YGFCQQFVRKVAGMDKQAKLSDLQTAAAGSFASAFAALALCPTELVKCRLQTMYEMEMSG 144
Query: 148 RFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFY 207
+ N +++ IL+ DG GFY G ++LL +P ++ Y
Sbjct: 145 KIAKSHNT----------IWSVVKGILKKDGPLGFYHGLSSTLLQEVPGYFFFFGGYELS 194
Query: 208 AEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQV---EGKNS-IILTFR 263
+ K+ V +SG +A ++ P+D I++R+QV GK + I T
Sbjct: 195 RSFFASGRSKDELGPVHLMLSGGVAGICLWLVVFPVDCIKSRIQVLSMYGKQAGFIGTLL 254
Query: 264 QLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKKLSLR 305
++ EG L GL A +I A P+ + V YE +K+ ++
Sbjct: 255 SVVRNEGIVALYSGLKATMIRAIPANGALFVAYEYSRKMMMK 296
Score = 32.0 bits (71), Expect = 0.73
Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 3/69 (4%)
Query: 35 VYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGITGLYRGFLVNTFTLI--SGQCYVT 92
V+P I++R+QV G + ++R +GI LY G I +G +V
Sbjct: 227 VFPVDCIKSRIQVLSMYGKQAGFIGTLLSVVRNEGIVALYSGLKATMIRAIPANGALFV- 285
Query: 93 TYELTRKFV 101
YE +RK +
Sbjct: 286 AYEYSRKMM 294
>gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens]
Length = 321
Score = 73.9 bits (180), Expect = 2e-13
Identities = 65/258 (25%), Positives = 110/258 (42%), Gaps = 28/258 (10%)
Query: 52 SLYHGTFDAFIKILRADGITGLYRGFLVNTFTLISGQC-YVTTYELTRK-FVADYSQSNT 109
S+ G F IL +G L+RG N + + Y Y ++ F + ++
Sbjct: 69 SVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSN 128
Query: 110 VKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDI 169
+ + + GSA+ + S+ PI +V + +++K VRG+ + T
Sbjct: 129 IVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQK--------VRGSKQMN-------TLQC 173
Query: 170 IRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYL--------CPKECPH 221
R + Q +G+RGFYRG AS I + + + Y + L K
Sbjct: 174 ARYVYQTEGIRGFYRGLTASYAG-ISETIICFAIYESLKKYLKEAPLASSANGTEKNSTS 232
Query: 222 IVFQAVSGPLAAATASILTNPMDVIRTRVQVEGKN--SIILTFRQLMAEEGPWGLMKGLS 279
+ L+ AS + P +VIRTR++ EG S + T R + EEG +GL
Sbjct: 233 FFGLMAAAALSKGCASCIAYPHEVIRTRLREEGTKYKSFVQTARLVFREEGYLAFYRGLF 292
Query: 280 ARIISATPSTIVIVVGYE 297
A++I P+T +++ YE
Sbjct: 293 AQLIRQIPNTAIVLSTYE 310
Score = 62.4 bits (150), Expect = 5e-10
Identities = 61/219 (27%), Positives = 97/219 (44%), Gaps = 17/219 (7%)
Query: 106 QSNTVKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRF-QVR-GNPEGQGVVAF 163
+ NT+ L AGG V T P++V+ L R + + QV G G G+V
Sbjct: 8 KENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRP 67
Query: 164 GQTK----DIIRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLS-YLCPKE 218
+++ IL+ +G + +RG +L+ P+ AV++ Y EQ + P
Sbjct: 68 TSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNS 127
Query: 219 CPHIVFQAVSGPLAAATASILTNPMDVIRTRVQVEGK------NSIILTFRQLMAEEGPW 272
+F A S AA + L NP+ +++TR+Q+E K + + R + EG
Sbjct: 128 NIVHIFSAGS---AAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIR 184
Query: 273 GLMKGLSARIISATPSTIVIVVGYESLKKLSLRPELVDS 311
G +GL+A + TI+ YESLKK L S
Sbjct: 185 GFYRGLTAS-YAGISETIICFAIYESLKKYLKEAPLASS 222
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 73.9 bits (180), Expect = 2e-13
Identities = 73/304 (24%), Positives = 122/304 (40%), Gaps = 38/304 (12%)
Query: 19 KFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSL--------YHGTFDAFIKILRADGI 70
K +V+G +++ +P L +TRLQVQ G+S+ Y G F A +I + +G+
Sbjct: 42 KPFVYGGLASIVAEFGTFPVDLTKTRLQVQ-GQSIDARFKEIKYRGMFHALFRICKEEGV 100
Query: 71 TGLYRGFLVNTFTLIS-GQCYVTTYE-LTRKFVADYSQSNTVKSLVAGGSASLVAQSITV 128
LY G S G + Y+ L R FV + +++ G + +++ +I
Sbjct: 101 LALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIAN 160
Query: 129 PIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVA 188
P DV+ + + QG + G I Q +G RG +RG V
Sbjct: 161 PTDVLKIRM------------------QAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVP 202
Query: 189 SLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRT 248
+ V P Y + L L I+ VS ++ +NP+DV+RT
Sbjct: 203 TAQRAAIVVGVELPVYDITKKHL-ILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRT 261
Query: 249 RV--------QVEGKNSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 300
R+ V+ + ++ EG + L KG + P I+ + YE LK
Sbjct: 262 RMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321
Query: 301 KLSL 304
+L +
Sbjct: 322 RLQI 325
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 73.9 bits (180), Expect = 2e-13
Identities = 73/304 (24%), Positives = 122/304 (40%), Gaps = 38/304 (12%)
Query: 19 KFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSL--------YHGTFDAFIKILRADGI 70
K +V+G +++ +P L +TRLQVQ G+S+ Y G F A +I + +G+
Sbjct: 39 KPFVYGGLASIVAEFGTFPVDLTKTRLQVQ-GQSIDARFKEIKYRGMFHALFRICKEEGV 97
Query: 71 TGLYRGFLVNTFTLIS-GQCYVTTYE-LTRKFVADYSQSNTVKSLVAGGSASLVAQSITV 128
LY G S G + Y+ L R FV + +++ G + +++ +I
Sbjct: 98 LALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIAN 157
Query: 129 PIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVA 188
P DV+ + + QG + G I Q +G RG +RG V
Sbjct: 158 PTDVLKIRM------------------QAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVP 199
Query: 189 SLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRT 248
+ V P Y + L L I+ VS ++ +NP+DV+RT
Sbjct: 200 TAQRAAIVVGVELPVYDITKKHL-ILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRT 258
Query: 249 RV--------QVEGKNSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLK 300
R+ V+ + ++ EG + L KG + P I+ + YE LK
Sbjct: 259 RMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 318
Query: 301 KLSL 304
+L +
Sbjct: 319 RLQI 322
>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
Length = 315
Score = 73.6 bits (179), Expect = 2e-13
Identities = 70/295 (23%), Positives = 129/295 (43%), Gaps = 25/295 (8%)
Query: 22 VFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSL---YHGTFDAFIKILRADGITGLYRGFL 78
+ GV+ ++ ++++P L++ R V G L Y+G I + DG+ GLY+G
Sbjct: 27 IAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLYQGVT 86
Query: 79 VNTFTL-ISGQCYVTTYELTRKFVAD--YSQSNTVKSLVAGGSASLVAQSITVPIDVVSQ 135
N + +S Y Y + + + + + LV+ A + IT P+ V
Sbjct: 87 PNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEYLVSAAEAGAMTLCITNPLWVTKT 146
Query: 136 HLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASLLTYIP 195
LM+Q V +P Q F D + +I + +G+RG Y+G+V L
Sbjct: 147 RLMLQYDA-------VVNSPHRQYKGMF----DTLVKIYKYEGVRGLYKGFVPGLFG-TS 194
Query: 196 NSAVWWPFYHF----YAEQLSYLCPKECPHIVFQAVSGPLAAATASILTNPMDVIRTRVQ 251
+ A+ + Y Y + ++ L + + + +V+ L+ A T P V+R R+Q
Sbjct: 195 HGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAA-LSKIFAVAATYPYQVVRARLQ 253
Query: 252 VEGK--NSIILTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKKLSL 304
+ + +I + +EG G KG++ +I TP+ + V YE++ L
Sbjct: 254 DQHMFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENVSHFLL 308
Score = 58.2 bits (139), Expect = 1e-08
Identities = 46/204 (22%), Positives = 80/204 (39%), Gaps = 31/204 (15%)
Query: 13 EHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSL------YHGTFDAFIKILR 66
E L+ ++ V M P + +TRL +Q + Y G FD +KI +
Sbjct: 116 ERLEATEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYK 175
Query: 67 ADGITGLYRGFLVNTFTLISGQCYVTTYELTRKFVADY------SQSNTVKSLVAGGSAS 120
+G+ GLY+GF+ F G YEL + + +Q +TV+ + +
Sbjct: 176 YEGVRGLYKGFVPGLFGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSK 235
Query: 121 LVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLR 180
+ A + T P VV L Q + + D+I + + +G+
Sbjct: 236 IFAVAATYPYQVVRARLQDQH-------------------MFYSGVIDVITKTWRKEGVG 276
Query: 181 GFYRGYVASLLTYIPNSAVWWPFY 204
GFY+G +L+ P + + Y
Sbjct: 277 GFYKGIAPNLIRVTPACCITFVVY 300
>gi|46094065 mitochondrial carrier family protein [Homo sapiens]
Length = 338
Score = 73.2 bits (178), Expect = 3e-13
Identities = 61/264 (23%), Positives = 114/264 (43%), Gaps = 45/264 (17%)
Query: 54 YHGTFDAFIKILRADGITGLYRGF-----LVNTFTLISGQCYVTTYELTRKFVADYSQSN 108
+ GT DAF KI+R +GI L+ G + T+I CY L R + ++
Sbjct: 84 FQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLR---SKLGENE 140
Query: 109 TVKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKD 168
T +VAG A A ++ P++++ + ++ ++ +
Sbjct: 141 TCIPIVAGIVARFGAVTVISPLELIRTKMQSKK-------------------FSYVELHR 181
Query: 169 IIRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKEC---PHIVFQ 225
+ + + DG +RG+ ++L +P SA++W Y + +LC K P +
Sbjct: 182 FVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKK---WLCEKSGLYEPTFMIN 238
Query: 226 AVSGPLAAATASILTNPMDVIRTRVQVE------------GKNSIILTFRQLMAEEGPWG 273
SG L+ + A++ T P DV++T+ Q + S + + ++A+ G G
Sbjct: 239 FTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSG 298
Query: 274 LMKGLSARIISATPSTIVIVVGYE 297
L GL R+I P+ +++ YE
Sbjct: 299 LFSGLIPRLIKIAPACAIMISTYE 322
Score = 47.0 bits (110), Expect = 2e-05
Identities = 48/212 (22%), Positives = 96/212 (45%), Gaps = 25/212 (11%)
Query: 110 VKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGN---------PEGQGV 160
++ ++A + +++ I P+DVV L Q G+ V N EG
Sbjct: 16 LQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNK 75
Query: 161 V------AFGQTKDIIRQILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYL 214
+ F T D +I++ +G++ + G +L+ +P + +++ Y +QLS L
Sbjct: 76 LWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCY----DQLSAL 131
Query: 215 CPKECPH--IVFQAVSGPLAAATASILTNPMDVIRTRVQVEGKNSIILTFR---QLMAEE 269
+ V+G +A A + +P+++IRT++Q + K S + R + ++E+
Sbjct: 132 LRSKLGENETCIPIVAGIVARFGAVTVISPLELIRTKMQSK-KFSYVELHRFVSKKVSED 190
Query: 270 GPWGLMKGLSARIISATPSTIVIVVGYESLKK 301
G L +G + ++ P + + YE LKK
Sbjct: 191 GWISLWRGWAPTVLRDVPFSAMYWYNYEILKK 222
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 72.0 bits (175), Expect = 6e-13
Identities = 68/302 (22%), Positives = 122/302 (40%), Gaps = 43/302 (14%)
Query: 22 VFGVAMTMMIRVSVYPFTLIRTRLQVQKGK-------SLYHGTFDAFIKILRADGITGLY 74
V G ++ R + PF +I+ R Q+Q + + YHG A +IL+ +G T +
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 75 RGFLVNTFTLIS-GQCYVTTYELTRKFV---ADYSQSNTVKSLVAGGSASLVAQSITVPI 130
+G + I G ++E+ + V + Y V GG A+ +A P+
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPV 139
Query: 131 DVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQILQADGLRGFYRGYVASL 190
DV+ RF +G P+ + + + + +++G + FY+G +L
Sbjct: 140 DVLRT------------RFAAQGEPK-----VYNTLRHAVGTMYRSEGPQVFYKGLAPTL 182
Query: 191 LTYIPNSAVWWPFYHFYAEQLSYLCPKECP--HIVFQAVSGPLAAATASILTNPMDVIRT 248
+ P + + + Y + P E + + G A + LT P+D+ +
Sbjct: 183 IAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKK 242
Query: 249 RVQVEGKNSIILTF-------------RQLMAEEGPWGLMKGLSARIISATPSTIVIVVG 295
R+QV G F +Q++ +EG G KGLS ++ A ST +
Sbjct: 243 RLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFS 302
Query: 296 YE 297
YE
Sbjct: 303 YE 304
Score = 66.6 bits (161), Expect = 3e-11
Identities = 53/193 (27%), Positives = 84/193 (43%), Gaps = 14/193 (7%)
Query: 114 VAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIRQI 173
VAG + LV +++ P DV+ +Q E++ R G RQI
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQH--ERLSRSDPSAKYHG--------ILQASRQI 69
Query: 174 LQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPLAA 233
LQ +G F++G+V + + I AV + + E + + V G LAA
Sbjct: 70 LQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAA 129
Query: 234 ATASILTNPMDVIRTRVQVEGKNSIILTFRQ----LMAEEGPWGLMKGLSARIISATPST 289
A++ +P+DV+RTR +G+ + T R + EGP KGL+ +I+ P
Sbjct: 130 CMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYA 189
Query: 290 IVIVVGYESLKKL 302
+ Y SLK L
Sbjct: 190 GLQFSCYSSLKHL 202
Score = 59.3 bits (142), Expect = 4e-09
Identities = 45/199 (22%), Positives = 91/199 (45%), Gaps = 26/199 (13%)
Query: 21 YVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFIKILRADGITGLYRGFLVN 80
+V G M ++V+P ++RTR Q +Y+ A + R++G Y+G
Sbjct: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPT 181
Query: 81 TFTL-----ISGQCYVTTYELTRKFV-ADYSQSNTVKSLVAGGSASLVAQSITVPIDVVS 134
+ + CY + L + + A+ ++ +++L+ G A ++++++T P+D+
Sbjct: 182 LIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFK 241
Query: 135 QHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTK------DIIRQILQADGLRGFYRGYVA 188
+ L ++G F+ AFGQ + D +Q+LQ +G GF++G
Sbjct: 242 KRL-------QVGGFE-------HARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSP 287
Query: 189 SLLTYIPNSAVWWPFYHFY 207
SLL ++ + Y F+
Sbjct: 288 SLLKAALSTGFMFFSYEFF 306
Score = 38.5 bits (88), Expect = 0.008
Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 13/101 (12%)
Query: 226 AVSGPLAAATASILTNPMDVIRTRVQVEGK-----------NSIILTFRQLMAEEGPWGL 274
AV+G ++ L +P DVI+ R Q++ + + I+ RQ++ EEGP
Sbjct: 19 AVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAF 78
Query: 275 MKG-LSARIISATPSTIVIVVGYESLKKLSLRPELVDSRHW 314
KG + A+I+S + + +E L +L R + D+R +
Sbjct: 79 WKGHVPAQILSIGYGAVQF-LSFEMLTELVHRGSVYDAREF 118
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.138 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,164,044
Number of Sequences: 37866
Number of extensions: 381088
Number of successful extensions: 1614
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1040
Number of HSP's gapped (non-prelim): 204
length of query: 314
length of database: 18,247,518
effective HSP length: 102
effective length of query: 212
effective length of database: 14,385,186
effective search space: 3049659432
effective search space used: 3049659432
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.