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Search of human proteins with 4508005
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4508005 tripartite motif-containing 26 [Homo sapiens]
(539 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4508005 tripartite motif-containing 26 [Homo sapiens] 1101 0.0
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi... 303 2e-82
gi|149193331 tripartite motif protein 15 [Homo sapiens] 281 1e-75
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi... 260 3e-69
gi|5730009 ret finger protein [Homo sapiens] 241 9e-64
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 241 2e-63
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 238 8e-63
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens] 235 7e-62
gi|15208660 tripartite motif protein 21 [Homo sapiens] 226 4e-59
gi|5454014 tripartite motif-containing 38 [Homo sapiens] 211 1e-54
gi|37622899 ring finger protein 137 [Homo sapiens] 197 2e-50
gi|21630277 tripartite motif-containing 11 [Homo sapiens] 197 2e-50
gi|112421127 tripartite motif-containing 58 [Homo sapiens] 194 2e-49
gi|157743261 tripartite motif-containing 75 [Homo sapiens] 189 7e-48
gi|22749269 ring finger protein 129 [Homo sapiens] 182 5e-46
gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens] 182 5e-46
gi|62865604 tripartite motif protein 31 [Homo sapiens] 182 7e-46
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa... 180 3e-45
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens] 179 7e-45
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens] 179 7e-45
gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s... 167 2e-41
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s... 166 5e-41
gi|117938316 tripartite motif-containing 22 [Homo sapiens] 160 3e-39
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens] 160 3e-39
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens] 160 3e-39
gi|51477690 tripartite motif-containing 6 and tripartite motif-c... 160 3e-39
gi|31542779 tripartite motif family-like 1 [Homo sapiens] 154 3e-37
gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens] 147 2e-35
gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo s... 147 3e-35
gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo s... 147 3e-35
>gi|4508005 tripartite motif-containing 26 [Homo sapiens]
Length = 539
Score = 1101 bits (2847), Expect = 0.0
Identities = 539/539 (100%), Positives = 539/539 (100%)
Query: 1 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPF 60
MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPF
Sbjct: 1 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPF 60
Query: 61 KKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL 120
KKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL
Sbjct: 61 KKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL 120
Query: 121 CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKK 180
CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKK
Sbjct: 121 CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKK 180
Query: 181 LQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVIS 240
LQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVIS
Sbjct: 181 LQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVIS 240
Query: 241 ELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLREF 300
ELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLREF
Sbjct: 241 ELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLREF 300
Query: 301 QGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPGVLGS 360
QGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPGVLGS
Sbjct: 301 QGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPGVLGS 360
Query: 361 KGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDEESLG 420
KGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDEESLG
Sbjct: 361 KGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDEESLG 420
Query: 421 DEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWANTSPEAEL 480
DEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWANTSPEAEL
Sbjct: 421 DEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWANTSPEAEL 480
Query: 481 FPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWLKWPGTRLLLRP 539
FPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWLKWPGTRLLLRP
Sbjct: 481 FPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWLKWPGTRLLLRP 539
>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
sapiens]
Length = 481
Score = 303 bits (777), Expect = 2e-82
Identities = 187/541 (34%), Positives = 284/541 (52%), Gaps = 66/541 (12%)
Query: 1 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISG----SRPVCPLC 56
MA++A + SL +EV C IC LR+PVTIDCGH FCR+C T I G P CPLC
Sbjct: 1 MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60
Query: 57 KKPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDD 116
K+PF+ + RP WQLA++VENIERL++ GE +C+ H EK++++CEDD
Sbjct: 61 KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGE-------EDVCQEHGEKIYFFCEDD 113
Query: 117 GKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILA 176
LCV+CRE+ EH HT +E AA P+RE+I L LR++R++IQ Q++ +
Sbjct: 114 EMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQV 173
Query: 177 ALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLA 236
L ++ +RQ +++EF +FL E++ LL QL + ++ R++F GE+ R +
Sbjct: 174 LLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFS 233
Query: 237 LVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRG 296
+I ELE K ++PA EL+ D R L R +K ++ + ++ +F + L LQR
Sbjct: 234 ALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQRE 293
Query: 297 LREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPG 356
++ F KL +L+Y+ ++LDPQ++ L LSED + ++ ++++ +PQ+FD
Sbjct: 294 MKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATC 353
Query: 357 VLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDE 416
VL G T G+ W V + + +G ED
Sbjct: 354 VLAHTGITGGRHTWVVSI-------------------------DLAHGGSCTVGVVSEDV 388
Query: 417 ESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWANTSP 476
+ G+ EE GVWA+RL+ + A S
Sbjct: 389 QRKGELRLRPEE------------------------------GVWAVRLAWGFVSALGSF 418
Query: 477 EAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWLKWPGTRLL 536
L +PR+V ++LDYE G VTFTNA ++E IYTFTA+FTR+++PF L G+
Sbjct: 419 PTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGLWGRGSSFS 478
Query: 537 L 537
L
Sbjct: 479 L 479
>gi|149193331 tripartite motif protein 15 [Homo sapiens]
Length = 465
Score = 281 bits (719), Expect = 1e-75
Identities = 178/542 (32%), Positives = 272/542 (50%), Gaps = 82/542 (15%)
Query: 1 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPI----SGSRPVCPLC 56
M + L+ + E C++C L D VTI CGH FCR C + + SG +CPLC
Sbjct: 1 MPATPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLC 60
Query: 57 KKPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDD 116
++ + E L L E CE H EK++++CE+D
Sbjct: 61 QEEEQAETPMAPVPLGPLGETY-----------------------CEEHGEKIYFFCEND 97
Query: 117 GKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILA 176
+ LCV CRE H+ HT +++A QP+R+++ + L L +RD+I+ + + + +
Sbjct: 98 AEFLCVFCREGPTHQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQV 157
Query: 177 ALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLA 236
L +++ ++ + FE+ Q L ++ LL +L +LEQ++ + R+++ ++ E+ RL
Sbjct: 158 LLTQIESKKHQVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLG 217
Query: 237 LVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRG 296
+ ELE K QQPA+EL+QD R +R K F + I+ + KK +F K+L+L
Sbjct: 218 AQVKELEEKCQQPASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEM 277
Query: 297 LREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPG 356
+R F L LE + +TLDPQ+AS L LSED K V YT KS P +FD P
Sbjct: 278 MRMFSENLAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPA 337
Query: 357 VLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDE 416
VLG GF+ G+ W+V+++ GDG
Sbjct: 338 VLGFPGFSSGRHRWQVDLQ---------------------------LGDG---------- 360
Query: 417 ESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWANTSP 476
C VGVA + V+RKG++ L EDGVWA+ +S WA+TSP
Sbjct: 361 ------------------GGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSP 402
Query: 477 EAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWLKWPGTRLL 536
+L + PR V +ALDYE G VT NA++QE I+TFTA+F+ ++ PF + G+ L
Sbjct: 403 GTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFAVWKKGSCLT 462
Query: 537 LR 538
L+
Sbjct: 463 LK 464
>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo
sapiens]
Length = 395
Score = 260 bits (664), Expect = 3e-69
Identities = 142/374 (37%), Positives = 220/374 (58%), Gaps = 11/374 (2%)
Query: 1 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISG----SRPVCPLC 56
MA++A + SL +EV C IC LR+PVTIDCGH FCR+C T I G P CPLC
Sbjct: 1 MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60
Query: 57 KKPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDD 116
K+PF+ + RP WQLA++VENIERL++ GE +C+ H EK++++CEDD
Sbjct: 61 KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGE-------EDVCQEHGEKIYFFCEDD 113
Query: 117 GKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILA 176
LCV+CRE+ EH HT +E AA P+RE+I L LR++R++IQ Q++ +
Sbjct: 114 EMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQV 173
Query: 177 ALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLA 236
L ++ +RQ +++EF +FL E++ LL QL + ++ R++F GE+ R +
Sbjct: 174 LLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFS 233
Query: 237 LVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRG 296
+I ELE K ++PA EL+ D R L R +K ++ + ++ +F + L LQR
Sbjct: 234 ALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQRE 293
Query: 297 LREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPG 356
++ F KL +L+Y+ ++LDPQ++ L LSED + ++ ++++ +PQ+FD
Sbjct: 294 MKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATC 353
Query: 357 VLGSKGFTWGKVYW 370
VL G T G+ W
Sbjct: 354 VLAHTGITGGRHTW 367
>gi|5730009 ret finger protein [Homo sapiens]
Length = 513
Score = 241 bits (616), Expect = 9e-64
Identities = 169/546 (30%), Positives = 270/546 (49%), Gaps = 80/546 (14%)
Query: 1 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPF 60
MA+ + L++E TC +CL Y +P+ +DCGH C +C + + CP C++ F
Sbjct: 1 MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETF 60
Query: 61 KKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL 120
+ ++RP LA++ + +++L+ ++ PG + +CE+HRE L YCE+D +
Sbjct: 61 PQRHMRPNRHLANVTQLVKQLRTERPSGPGG------EMGVCEKHREPLKLYCEEDQMPI 114
Query: 121 CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKK 180
CV+C SREHR H+ + +E+A + +E+I N L L+R +D + +A+GE L
Sbjct: 115 CVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSL 174
Query: 181 LQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVIS 240
Q +R+ IV EFEQ + L+E E LL +L +L+ + ++ ++ L+ +I+
Sbjct: 175 TQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIA 234
Query: 241 ELEGKAQQPAAELMQDTRDFLNRYPRKKF---WVGKPIARVVKKKTGEFSDKLLSLQRGL 297
+LE K QQP EL+QD D L+R R + W+ P +++K F+ K L L L
Sbjct: 235 QLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPP---DLQEKIHIFAQKCLFLTESL 291
Query: 298 REFQGKL---------LRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHP 348
++F K+ LR+ + +V VTLDP +A L LS++ + V Y+ L + +P
Sbjct: 292 KQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNP 351
Query: 349 QQFDCEPGVLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYD 408
++F+ P VLGS F G+ YWEVEV GD+ +
Sbjct: 352 ERFNLFPCVLGSPCFIAGRHYWEVEV-----------GDKAK------------------ 382
Query: 409 DWETDEDEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRL-SS 467
W E+S V RKG ++ P++G WA+ L
Sbjct: 383 -WTIGVCEDS---------------------------VCRKGGVTSAPQNGFWAVSLWYG 414
Query: 468 SGIWANTSPEAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFT-ATFTRRLVPFL 526
WA TSP L +RVGI LDY+ G V+F N + +TF+ ATF + P+
Sbjct: 415 KEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYF 474
Query: 527 WLKWPG 532
L + G
Sbjct: 475 SLSYSG 480
>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
Length = 518
Score = 241 bits (614), Expect = 2e-63
Identities = 174/555 (31%), Positives = 274/555 (49%), Gaps = 91/555 (16%)
Query: 2 ATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPFK 61
+T+A L +L+ E +CS+CL+YL++PV I+CGH FC++C T CP+C+K +
Sbjct: 15 STAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSR 74
Query: 62 KENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLLC 121
++RP QL S+VE ++L+ V R+ +D LC +H E L +C +D + +C
Sbjct: 75 YRSLRPNRQLGSMVEIAKQLQA--------VKRKIRDESLCPQHHEALSLFCYEDQEAVC 126
Query: 122 VMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKKL 181
++C S HR HT V ++ A Q ++EK+ L L + +I ++ E + +
Sbjct: 127 LICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLV 186
Query: 182 QDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELAR-LALVIS 240
+ +RQ I+ EFE+ H+ L E ++ LL +L + EQ++ + R + + +G+ R LA + +
Sbjct: 187 ESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQ-RLRENAAHLGDKRRDLAHLAA 245
Query: 241 ELEGKAQQPAAELMQDTRDFLNRYPRKKFW----------------VGKPIARVVKKKTG 284
E+EGK Q E+++D + L + +KF + K I R K KT
Sbjct: 246 EVEGKCLQSGFEMLKDVKSTLEKNIPRKFGGSLSTICPRDHKALLGLVKEINRCEKVKTM 305
Query: 285 EFSDKLLSLQRGLREFQGK---LLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSL- 340
E + + L++ F + L + L+ VTLDP++A L LSED K V +
Sbjct: 306 EVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETR 365
Query: 341 YKSAYLHPQQFDCEPGVLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEE 400
+ P++F P VL ++GFT G+ Y
Sbjct: 366 LRDLPDTPRRFTFYPCVLATEGFTSGRHY------------------------------- 394
Query: 401 AGYGDGYDDWETDEDEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGV 460
WE + +GD+ VGV RDSV RKG+L+ PE G
Sbjct: 395 ---------WEVE-----VGDKTH------------WAVGVCRDSVSRKGELTPLPETGY 428
Query: 461 WALRLSSSGIWA-NTSPEAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFT 519
W +RL + +A T+P L ++P+RVGI LDYE GT++F N + IYTFT TFT
Sbjct: 429 WRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFT 488
Query: 520 RRLVPFLWLKWPGTR 534
+L P L +PG R
Sbjct: 489 EKLWP---LFYPGIR 500
>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
Length = 488
Score = 238 bits (608), Expect = 8e-63
Identities = 168/536 (31%), Positives = 271/536 (50%), Gaps = 83/536 (15%)
Query: 2 ATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPFK 61
+T+A L +L+ E +CS+CL+YL++PV I+CGH FC++C T CP+C+K +
Sbjct: 15 STAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSR 74
Query: 62 KENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLLC 121
++RP QL S+VE ++L+ V R+ +D LC +H E L +C +D + +C
Sbjct: 75 YRSLRPNRQLGSMVEIAKQLQA--------VKRKIRDESLCPQHHEALSLFCYEDQEAVC 126
Query: 122 VMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKKL 181
++C S HR HT V ++ A Q ++EK+ L L + +I ++ E + +
Sbjct: 127 LICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLV 186
Query: 182 QDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELAR-LALVIS 240
+ +RQ I+ EFE+ H+ L E ++ LL +L + EQ++ + R + + +G+ R LA + +
Sbjct: 187 ESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQ-RLRENAAHLGDKRRDLAHLAA 245
Query: 241 ELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLREF 300
E+EGK Q E+++D + L + + K ++ ++K F + +L++ L++
Sbjct: 246 EVEGKCLQSGFEMLKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQ- 304
Query: 301 QGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSL-YKSAYLHPQQFDCEPGVLG 359
L+ D VTLDP++A L LSED K V + + P++F P VL
Sbjct: 305 ---LIAD-------VTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLA 354
Query: 360 SKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDEESL 419
++GFT G+ Y WE + +
Sbjct: 355 TEGFTSGRHY----------------------------------------WEVE-----V 369
Query: 420 GDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWA-NTSPEA 478
GD+ VGV RDSV RKG+L+ PE G W +RL + +A T+P
Sbjct: 370 GDKTH------------WAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAATTTPFT 417
Query: 479 ELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWLKWPGTR 534
L ++P+RVGI LDYE GT++F N + IYTFT TFT +L P L +PG R
Sbjct: 418 PLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWP---LFYPGIR 470
>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
Length = 511
Score = 235 bits (600), Expect = 7e-62
Identities = 161/546 (29%), Positives = 260/546 (47%), Gaps = 73/546 (13%)
Query: 10 LEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDV--RPISGSRPV----------CPLCK 57
L+ E TCSICL+ R+PV+++CGH FCR+C RP +GS CP C+
Sbjct: 23 LQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQCR 82
Query: 58 KPFKKENIRPVWQLASLVENIERLKVDK---GRQPGEVTREQQDAKLCERHREKLHYYCE 114
+P + +RP QLA++ + R + G + + A C +H E YC+
Sbjct: 83 EPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYCQ 142
Query: 115 DDGKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADI 174
DDG+ +CV+C +REHR H + +++A Q +E + + L L+++ + + F++ + +
Sbjct: 143 DDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKES 202
Query: 175 LAALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELAR 234
LK++ +++ + AEF+ FL E+E LL +L +L +E+ + + + ++ E+ +
Sbjct: 203 KELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQ 262
Query: 235 LALVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQ 294
L+ + S+++ AQ+P + +Q+ + L+R ++ +K K S K L+
Sbjct: 263 LSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLK 322
Query: 295 RGLREFQGKLLRDLEYKT-VSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDC 353
L++F+ L +LE + V +TLDP +A+ L LS D K V + HP +FD
Sbjct: 323 GMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDT 382
Query: 354 EPGVLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETD 413
VL S GF+ G+ +WEV E G DG+
Sbjct: 383 NTRVLASCGFSSGRHHWEV---------------------------EVGSKDGW------ 409
Query: 414 EDEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWAN 473
GVAR+SV+RKG PE+GVWAL+L+ WA
Sbjct: 410 ------------------------AFGVARESVRRKGLTPFTPEEGVWALQLNGGQYWAV 445
Query: 474 TSPEAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWLKWPGT 533
TSPE RV +ALD E G V+F E +YTF F R+ P + GT
Sbjct: 446 TSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVCSTGT 505
Query: 534 RLLLRP 539
L + P
Sbjct: 506 YLRIWP 511
>gi|15208660 tripartite motif protein 21 [Homo sapiens]
Length = 475
Score = 226 bits (576), Expect = 4e-59
Identities = 170/531 (32%), Positives = 252/531 (47%), Gaps = 92/531 (17%)
Query: 1 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPF 60
MA++A L + EEVTC ICLD +PV+I+CGH FC+ C + V GS VCP+C++ F
Sbjct: 1 MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGS--VCPVCRQRF 58
Query: 61 KKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL 120
+N+RP QLA++V N++ + + RE + C H E+LH +CE DGK L
Sbjct: 59 LLKNLRPNRQLANMVNNLKEISQE--------AREGTQGERCAVHGERLHLFCEKDGKAL 110
Query: 121 CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKK 180
C +C +SR+HR H V +E+AAQ ++EK+ L LRR ++ + + + K
Sbjct: 111 CWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKT 170
Query: 181 LQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVIS 240
++ Q+ I AEF Q FL E E+ L++L K E+E + +++ + L +IS
Sbjct: 171 VETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELIS 230
Query: 241 ELEGKAQQPAAELMQDTRDFLNR---YPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGL 297
EL+ + A EL+Q+ L R + K + P R V G
Sbjct: 231 ELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPG------------- 277
Query: 298 REFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPGV 357
L + L V +TLDP +A+ +L LSED + V +S + ++FD P V
Sbjct: 278 ------LKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMV 331
Query: 358 LGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDEE 417
LG++ F GK YWEV+V G + W+
Sbjct: 332 LGAQHFHSGKHYWEVDVT------------------------------GKEAWD------ 355
Query: 418 SLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIW-ANTSP 476
+GV RDSV+RKG L + G W + L + + A T P
Sbjct: 356 ---------------------LGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYP 394
Query: 477 EAELFPALRPRRVGIALDYEGGTVTFTN-AESQELIYTFT-ATFTRRLVPF 525
+ L + P +VGI LDYE G V+F N + LIY+F+ FT L PF
Sbjct: 395 QTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPF 445
>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
Length = 465
Score = 211 bits (537), Expect = 1e-54
Identities = 162/534 (30%), Positives = 243/534 (45%), Gaps = 94/534 (17%)
Query: 1 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPV------CP 54
MA++ + + EE TCSICL + +PV+I+CGH +C C TD + + CP
Sbjct: 1 MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP 60
Query: 55 LCKKPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCE 114
C+ PF +++RP QL SL+E + +E CE H E+ H +CE
Sbjct: 61 QCRAPFHMDSLRPNKQLGSLIEAL---------------KETDQEMSCEEHGEQFHLFCE 105
Query: 115 DDGKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADI 174
D+G+L+C C + +H+ HT L+E Q ++EK+ ++ L++ D+ + I
Sbjct: 106 DEGQLICWRCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRI 165
Query: 175 LAALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVG-ELA 233
+K+Q QRQ I ++F+ FL E E+ L +L K EQ+ T R + G+G +
Sbjct: 166 TKWKEKVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQ-TLSRLRDYEAGLGLKSN 224
Query: 234 RLALVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSL 293
L I ELE K Q A +L+Q+ D L+R + VK +T E L
Sbjct: 225 ELKSHILELEEKCQGSAQKLLQNVNDTLSR------------SWAVKLETSEAVSLELHT 272
Query: 294 QRGLREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDC 353
+ + + + L VSVTLDP +A L LSED + VT ++ ++F
Sbjct: 273 MCNVSKLYFDVKKMLRSHQVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTA 332
Query: 354 EPGVLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETD 413
P VLG +GFT G+ Y+EV+V G G G+D
Sbjct: 333 FPCVLGCEGFTSGRRYFEVDV---------------------------GEGTGWD----- 360
Query: 414 EDEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRL-SSSGIWA 472
+GV ++V+R + P+ G W LRL G A
Sbjct: 361 -------------------------LGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVA 395
Query: 473 NTSPEAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTF-TATFTRRLVPF 525
TSP L +P VGI LDYE G V+F N + I+TF A+F+ L P+
Sbjct: 396 LTSPPTSLHLHEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPY 449
>gi|37622899 ring finger protein 137 [Homo sapiens]
Length = 485
Score = 197 bits (502), Expect = 2e-50
Identities = 158/543 (29%), Positives = 249/543 (45%), Gaps = 100/543 (18%)
Query: 1 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRP----VCPLC 56
M +A + ++ EEV C IC+ +LR+P++IDCGH FC SC + + I G CPLC
Sbjct: 1 MDPTALVEAIVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLC 60
Query: 57 KKPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDD 116
+ P + N+RP WQLA++VE + L++ G LCERH EKL +C++D
Sbjct: 61 RAPVQPRNLRPNWQLANVVEKVRLLRLHPGM--------GLKGDLCERHGEKLKMFCKED 112
Query: 117 GKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILA 176
++C C +S EH H+ V ME A ++ ++ L L++++++ + GE A
Sbjct: 113 VLIMCEACSQSPEHEAHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEV-GERKRTA 171
Query: 177 ALK-KLQDQRQYIVAEFEQGHQFLRERE-------EHLLEQLAKLEQELTEGREKFK--- 225
K +++ ++Q IV EFE+ + L +++ + LA L++E E +K +
Sbjct: 172 TWKIQVETRKQSIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNH 231
Query: 226 SRGVGELARLALVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGE 285
S + + L +I+EL+ ++Q+P ++QD ++ LNR +PI+ +K
Sbjct: 232 SELIQQSQVLWRMIAELKERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTDCRV 291
Query: 286 FSDKLLSLQRGLREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAY 345
GLRE L+ V LDP +A L +SED K V Y +
Sbjct: 292 L---------GLREI-------LKTYAADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLP 335
Query: 346 LHPQQFDCEPGVLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGD 405
+P++F VLGS+ + G+ YWEVEV GD E G
Sbjct: 336 DNPERFYRYNIVLGSQCISSGRHYWEVEV-----------GDRSEWG------------- 371
Query: 406 GYDDWETDEDEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRL 465
+GV + +V RK + L P G W +RL
Sbjct: 372 ---------------------------------LGVCKQNVDRKEVVYLSPHYGFWVIRL 398
Query: 466 SSSGIW-ANTSPEAELFPALRPRRVGIALDYEGGTVTFTN-AESQELIYTFTA-TFTRRL 522
+ A T L + PRRVGI +DYE ++F N + I+TF F RL
Sbjct: 399 RKGNEYRAGTDEYPILSLPVPPRRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFPGRL 458
Query: 523 VPF 525
+P+
Sbjct: 459 LPY 461
>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
Length = 468
Score = 197 bits (501), Expect = 2e-50
Identities = 154/506 (30%), Positives = 223/506 (44%), Gaps = 85/506 (16%)
Query: 9 SLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPFKKENIRPV 68
+L+EE TC+ICLDY DPV DCGH FCR C CP C++ + N+RP
Sbjct: 9 NLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQRNLRPN 68
Query: 69 WQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLLCVMCRESR 128
LA + E RL P V + +C HRE L +C D+ +LLC C S
Sbjct: 69 RPLAKMAEMARRL-----HPPSPVPQG-----VCPAHREPLAAFCGDELRLLCAACERSG 118
Query: 129 EHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKKLQDQRQYI 188
EH H ++ AA+ + K+ L LR+ FQA+ + + K ++ QRQ +
Sbjct: 119 EHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNV 178
Query: 189 VAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVISELEGKAQQ 248
+ EFE+ + L E E+ LL++L + E E+ + + + A LA +I+ELEG+ Q
Sbjct: 179 LGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQL 238
Query: 249 PAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLREFQGKLLRDL 308
PA L+QD +D L R K + + ++ ++ L LR F+G
Sbjct: 239 PALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVC-----RVPGLVETLRRFRG------ 287
Query: 309 EYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPGVLGSKGFTWGKV 368
VTLDP +A+ L LSED + V L ++ P++FD P VLG + FT G+
Sbjct: 288 -----DVTLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRH 342
Query: 369 YWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDEESLGDEEEEEEE 428
YW E +GD
Sbjct: 343 YW---------------------------------------------EVEVGDRT----- 352
Query: 429 EEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWANTSPEAELFPALRPRR 488
S +GV R++V RK L +G W L S + N+S A PRR
Sbjct: 353 -------SWALGVCRENVNRKEKGELSAGNGFWILVFLGS--YYNSSERALAPLRDPPRR 403
Query: 489 VGIALDYEGGTVTFTNAESQELIYTF 514
VGI LDYE G ++F +A L++ F
Sbjct: 404 VGIFLDYEAGHLSFYSATDGSLLFIF 429
>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
Length = 486
Score = 194 bits (492), Expect = 2e-49
Identities = 157/544 (28%), Positives = 239/544 (43%), Gaps = 89/544 (16%)
Query: 1 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPIS----GSRPVCPLC 56
MA + P L E+ C +CLD+L++PV++DCGH FC C ++ S G CP C
Sbjct: 1 MAWAPPGERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQC 60
Query: 57 KKPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDD 116
+ PF+ RP QLA LVE++ RL + G PG A+ C RH E L +CE+D
Sbjct: 61 RGPFRPSGFRPNRQLAGLVESVRRLGLGAG--PG--------ARRCARHGEDLSRFCEED 110
Query: 117 GKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILA 176
LC +C EHR H +++AA ++ K+ L +R++ + +A +
Sbjct: 111 EAALCWVCDAGPEHRTHRTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVI 170
Query: 177 ALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLA 236
+K++ QRQ EFE+ FL + E+ L +L E+ + + KSR V + L
Sbjct: 171 WKEKVEMQRQRFRLEFEKHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALK 230
Query: 237 LVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRG 296
+ EL+ + Q+PA L++ R L+R K + R ++ + K G
Sbjct: 231 ELADELQERCQRPALGLLEGVRGVLSR--------SKAVTR-LEAENIPMELKTACCIPG 281
Query: 297 LREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPG 356
RE LLR + V V LDP +A L L+ D + V ++ +P++FD P
Sbjct: 282 RRE----LLRKFQ---VDVKLDPATAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPC 334
Query: 357 VLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDE 416
+LG + F+ G+ YWEV V G+G +W +
Sbjct: 335 ILGLQSFSSGRHYWEVLV-----------------------------GEG-AEWGLGVCQ 364
Query: 417 ESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWAL-RLSSSGIWANTS 475
++L + E E +GVWAL L + S
Sbjct: 365 DTLPRKGETTPSPE---------------------------NGVWALWLLKGNEYMVLAS 397
Query: 476 PEAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWLKWPGTRL 535
P L PR +GI LDYE G ++F N IYTF F+ L P+ ++ T L
Sbjct: 398 PSVPLLQLESPRCIGIFLDYEAGEISFYNVTDGSYIYTFNQLFSGLLRPYFFI-CDATPL 456
Query: 536 LLRP 539
+L P
Sbjct: 457 ILPP 460
>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
Length = 468
Score = 189 bits (479), Expect = 7e-48
Identities = 140/528 (26%), Positives = 239/528 (45%), Gaps = 76/528 (14%)
Query: 1 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPF 60
MA +A L L+ E CSICLDYL DPVTI+CGH FCRSC CP+C+
Sbjct: 1 MAVAAALTGLQAEAKCSICLDYLSDPVTIECGHNFCRSCIQQSWLDLQELFPCPVCRHQC 60
Query: 61 KKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL 120
++ + R QL ++E + L+ K + R+Q++ LCE+H + L +C++D +L
Sbjct: 61 QEGHFRSNTQLGRMIEIAKLLQSTKSNK-----RKQEETTLCEKHNQPLSVFCKEDLMVL 115
Query: 121 CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKK 180
C +C + +H+ H +EKAA +R++ +++ L++ +Q + L +
Sbjct: 116 CPLCTQPPDHQGHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPLELREM 175
Query: 181 LQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVIS 240
+++QRQ + +EFE +QFL ++ +L +LA+ E++ + + A L +S
Sbjct: 176 VENQRQELSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLS 235
Query: 241 ELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLREF 300
++ ++ EL+ + F Y + + +K+ F + +LQR +++F
Sbjct: 236 KVVELSELSELELLSQIKIF---YESENESSPSIFSIHLKRDGCSFPPQYSALQRIIKKF 292
Query: 301 QGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPGVLGS 360
+ V + LDP++A L +SED K V +T + P++F +P VLG
Sbjct: 293 K-----------VEIILDPETAHPNLIVSEDKKRVRFTKRKQKVPGFPKRFTVKPVVLGF 341
Query: 361 KGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDEESLG 420
F G+ +WE+EV GD+ E W
Sbjct: 342 PYFHSGRHFWEIEV-----------GDKSE-------------------W---------- 361
Query: 421 DEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWANTSPEAEL 480
+G+ +DS+ K + W + L G A + L
Sbjct: 362 -----------------AIGICKDSLPTKARRPSSAQQECWRIELQDDGYHAPGAFPTPL 404
Query: 481 FPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWL 528
++ R +GI LDYE G ++F N + I TFT TFT L P+ ++
Sbjct: 405 LLEVKARAIGIFLDYEMGEISFYNMAEKSHICTFTDTFTGPLRPYFYV 452
>gi|22749269 ring finger protein 129 [Homo sapiens]
Length = 471
Score = 182 bits (463), Expect = 5e-46
Identities = 146/531 (27%), Positives = 244/531 (45%), Gaps = 94/531 (17%)
Query: 7 LRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSC-TTDVRPISGSRPVCPLCKKPFKKENI 65
L +L+EE +C ICL+YL+DPVTI+CGH FCRSC + + + + P CP+C+ F ++
Sbjct: 7 LVNLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDDTFP-CPVCRFCFPYKSF 65
Query: 66 RPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLLCVMCR 125
R QL +L E ++L++ + ++ + Q++ +CE+H + L +C D ++LC C
Sbjct: 66 RRNPQLRNLTEIAKQLQIRRSKR-----KRQKENAMCEKHNQFLTLFCVKDLEILCTQCS 120
Query: 126 ESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKKLQDQR 185
S +H+ H ++KAA HRE + L LR + ++++ + + KK++ +R
Sbjct: 121 FSTKHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKR 180
Query: 186 QYIVAEFEQGHQFLREREEHLLEQ--------LAKLEQELTEGREKFKSRGVGELARLAL 237
+ I +EFEQ FL+ +E +L Q LAKL + L E + ++ L
Sbjct: 181 EEINSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDY--------VSTLKH 232
Query: 238 VISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGL 297
++ E+EGK+ Q EL+ + ++Y K + + + K + L R +
Sbjct: 233 LLREVEGKSVQSNLELLTQAKSMHHKYQNLK--CPELFSFRLTKYGFSLPPQYSGLDRII 290
Query: 298 REFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPGV 357
+ FQ V V LD +A L +SED K V Y ++ P++F P V
Sbjct: 291 KPFQ-----------VDVILDLNTAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAV 339
Query: 358 LGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDEE 417
LGS+ F+ G R W E E G + + W
Sbjct: 340 LGSQRFSSG---------RHYW--------EVEVGNKPK-------------W------- 362
Query: 418 SLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWAL-RLSSSGIWANTSP 476
++GV +D + R G WA+ R SG A+
Sbjct: 363 --------------------ILGVCQDCLLRNWQDQPSVLGGFWAIGRYMKSGYVASGPK 402
Query: 477 EAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLW 527
+L P ++P ++GI LDYE G ++F N + ++YTF FT + P+ +
Sbjct: 403 TTQLLPVVKPSKIGIFLDYELGDLSFYNMNDRSILYTFNDCFTEAVWPYFY 453
>gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]
Length = 630
Score = 182 bits (463), Expect = 5e-46
Identities = 138/497 (27%), Positives = 233/497 (46%), Gaps = 59/497 (11%)
Query: 53 CPLCKKPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYY 112
CP C+K F + + RP QLA++V+ I ++ GR VT D +C +H+E L +
Sbjct: 183 CPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRG-SRVT----DQGICPKHQEALKLF 237
Query: 113 CEDDGKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEA 172
CE D + +CV+CRESR H+ H+ V +E+ Q ++ K+ H+ LR+ + +Q +AK E
Sbjct: 238 CEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEER 297
Query: 173 DILAALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGEL 232
+ +++ + + +EF + +FL E + L +L ++ + SR +
Sbjct: 298 RVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQA 357
Query: 233 ARLALVISELEGKAQQPAAELMQDTRDFLNRYPR-----KKFWVGKPIARVVKKKTGEFS 287
A+L+ +++E + ++QQ L+QD ++ NR + W P + + +F
Sbjct: 358 AQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDP----CQPHSHDFL 413
Query: 288 DKLLSLQRGLREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLH 347
+ +++ R F + V +TLDP +A L LS D + V + H
Sbjct: 414 TDAI-VRKMSRMF-------CQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADH 465
Query: 348 PQQFDCEPGVLGSKGFTWGKVYWEVEV-EREGWSEDEEEGDEEEEGEEEEEEEEAGYGDG 406
P++F + VLG++GF G+ YWEVEV R GW+ E +E+ G G
Sbjct: 466 PKRFSADCCVLGAQGFRSGRHYWEVEVGGRRGWAVGAAR-------ESTHHKEKVGPGG- 517
Query: 407 YDDWETDEDEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRP--EDGVWALR 464
S+G + +R+ L +P + VW +
Sbjct: 518 ----------SSVGSGDASSSRHHHR--------------RRRLHLPQQPLLQREVWCVG 553
Query: 465 LSSSGIWANTSPEAELF-PALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFT-RRL 522
+ A +S E L P+ +PRR G+ LDYE G + F NAE+ ++TF+A F R+
Sbjct: 554 TNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAETLAHVHTFSAAFLGERV 613
Query: 523 VPFLWLKWPGTRLLLRP 539
PF + GTR+ L P
Sbjct: 614 FPFFRVLSKGTRIKLCP 630
Score = 58.9 bits (141), Expect = 1e-08
Identities = 23/41 (56%), Positives = 30/41 (73%)
Query: 3 TSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDV 43
T P+++L+EE C+ICLDY DPV+I CGH FCR C T +
Sbjct: 7 TPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQL 47
Score = 51.6 bits (122), Expect = 2e-06
Identities = 36/70 (51%), Positives = 41/70 (58%), Gaps = 9/70 (12%)
Query: 381 EDEEEGDE-----EEEGEEEEEEEEAGYGDGYDDWETDEDEESLGDEEEEEEEEEEEVLE 435
EDEE+ DE EEE EEEE E G G G+D DED E GD EEE EEEEE V
Sbjct: 51 EDEEDRDELDREEEEEDGEEEEVEAVGAGAGWDTPMRDEDYE--GDMEEEVEEEEEGVFW 108
Query: 436 SCMVGVARDS 445
+ G++R S
Sbjct: 109 TS--GMSRSS 116
Score = 41.6 bits (96), Expect = 0.002
Identities = 33/87 (37%), Positives = 43/87 (49%), Gaps = 27/87 (31%)
Query: 370 WEVEVEREGWSED-EEEGDEEEEG-------------------EEEEEEEEAGYGDGYDD 409
W+ + E + D EEE +EEEEG EEE+EEE+ Y G
Sbjct: 82 WDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNMDYVWEEEDEEEDLDYYLG--- 138
Query: 410 WETDEDEESL-GDEEEEEEEEEEEVLE 435
D +EE L G++EE+EEE EEV E
Sbjct: 139 ---DMEEEDLRGEDEEDEEEVLEEVEE 162
Score = 38.1 bits (87), Expect = 0.021
Identities = 32/78 (41%), Positives = 39/78 (50%), Gaps = 20/78 (25%)
Query: 378 GWS----EDEEEGDEEEEGEEEEEEEEAGYGDGYDDWET------DEDEES-----LGDE 422
GW +++ EGD EEE EEEEE G W+ +EDEE LGD
Sbjct: 81 GWDTPMRDEDYEGDMEEEVEEEEEGVFWTSGMSRSSWDNMDYVWEEEDEEEDLDYYLGDM 140
Query: 423 EEEE-E----EEEEEVLE 435
EEE+ E+EEEVLE
Sbjct: 141 EEEDLRGEDEEDEEEVLE 158
Score = 34.3 bits (77), Expect = 0.30
Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 15/84 (17%)
Query: 411 ETDEDEESLGDEEEEEEEEEEEVLESCMVGVARDSVKR----KGDLS---LRPEDGV-WA 462
E +ED + L D EEEEE+ EEE +E+ G D+ R +GD+ E+GV W
Sbjct: 51 EDEEDRDEL-DREEEEEDGEEEEVEAVGAGAGWDTPMRDEDYEGDMEEEVEEEEEGVFWT 109
Query: 463 LRLSSSG------IWANTSPEAEL 480
+S S +W E +L
Sbjct: 110 SGMSRSSWDNMDYVWEEEDEEEDL 133
>gi|62865604 tripartite motif protein 31 [Homo sapiens]
Length = 425
Score = 182 bits (462), Expect = 7e-46
Identities = 106/307 (34%), Positives = 166/307 (54%), Gaps = 7/307 (2%)
Query: 1 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPF 60
MA+ + L+EEV C ICLD L+ PVTIDCGH FC C T + S CPLCK
Sbjct: 1 MASGQFVNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSV 60
Query: 61 KKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL 120
+K IR L +LVE I+ L Q EV ++++A C RH+E HY+CEDDGK L
Sbjct: 61 RKNAIRFNSLLRNLVEKIQAL------QASEVQSKRKEAT-CPRHQEMFHYFCEDDGKFL 113
Query: 121 CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKK 180
C +CRES++H+ H L+E+AAQ ++ +I + L++ + +A+G + +
Sbjct: 114 CFVCRESKDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKAQGVHRVDVFTDQ 173
Query: 181 LQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVIS 240
++ ++Q I+ EFE HQ L E + LL ++ L E TE + + + +L L ++
Sbjct: 174 VEHEKQRILTEFELLHQVLEEEKNFLLSRIYWLGHEGTEAGKHYVASTEPQLNDLKKLVD 233
Query: 241 ELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLREF 300
L+ K P +L++D + L R +F P+ ++KK E + S+ L++F
Sbjct: 234 SLKTKQNMPPRQLLEDIKVVLCRSEEFQFLNPTPVPLELEKKLSEAKSRHDSITGSLKKF 293
Query: 301 QGKLLRD 307
+ +L D
Sbjct: 294 KDQLQAD 300
>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
sapiens]
Length = 474
Score = 180 bits (456), Expect = 3e-45
Identities = 160/547 (29%), Positives = 240/547 (43%), Gaps = 100/547 (18%)
Query: 10 LEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPFKKENIRPVW 69
++EE+TC ICLDY +DPV+I+CGH FCR C G CP C+ P +RP W
Sbjct: 6 IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNW 65
Query: 70 QLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLLCVMCRESRE 129
LA L E +R ++ PG LC RH E L +CEDD + +C++CRES+E
Sbjct: 66 ALARLTEKTQRRRLGPV-PPG----------LCGRHWEPLRLFCEDDQRPVCLVCRESQE 114
Query: 130 HRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKKLQDQRQYIV 189
H+ H +++A + +REK+L L K+ Q + K++ QR I
Sbjct: 115 HQTHAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRIS 174
Query: 190 AEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVISELEGKAQQP 249
EF + H FL E E+ L++L K E+E + + + +A L +I E+ K+Q P
Sbjct: 175 TEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAP 234
Query: 250 AAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLREFQ-------- 301
EL+Q+ ++ L R + VK KT ++ ++ L+ FQ
Sbjct: 235 TLELLQNPKEVLT---RSEIQDVNYSLEAVKVKT---VCQIPLMKEMLKRFQVAVNLAED 288
Query: 302 ---GKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVT-YTSLYKSAYLHPQQFDCEPGV 357
KL+ E + V T SAS + S W + + K+A++ ++F P V
Sbjct: 289 TAHPKLVFSQEGRYVKNT---ASASSWPVFSSAWNYFAGWRNPQKTAFV--ERFQHLPCV 343
Query: 358 LGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDEE 417
LG FT GK YWEVE D E
Sbjct: 344 LGKNVFTSGKHYWEVE-------------------------------------SRDSLEV 366
Query: 418 SLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIW-----A 472
++G V ++G+ D K D+ + WA+ S++G W
Sbjct: 367 AVG------------VCREDVMGIT-DRSKMSPDVGI------WAIYWSAAGYWPLIGFP 407
Query: 473 NTSPEAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWLKWPG 532
T + E PAL RVG+ LD G V+F +A ++TF+ + RL PF WL P
Sbjct: 408 GTPTQQE--PAL--HRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFFWLS-PL 462
Query: 533 TRLLLRP 539
L++ P
Sbjct: 463 ASLVIPP 469
>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
Length = 488
Score = 179 bits (453), Expect = 7e-45
Identities = 127/385 (32%), Positives = 199/385 (51%), Gaps = 32/385 (8%)
Query: 3 TSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTT-----DVRPISGSRPVCPLCK 57
TS L + EEVTC ICL+ L +P++IDCGH FC++C T V G R CP+C+
Sbjct: 2 TSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERS-CPVCQ 60
Query: 58 KPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDG 117
++ N+RP LA++V + + + G+Q A LC H EKL +C++DG
Sbjct: 61 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQ--------LKAVLCADHGEKLQLFCQEDG 112
Query: 118 KLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAA 177
K++C +C S+EHR H L+E+ AQ ++EK L L+ + + + A +
Sbjct: 113 KVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSW 172
Query: 178 LKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGR---EKFKSRGVGELAR 234
+++ +R I EF Q L E+ +L KLEQE +G E+ ++ V +
Sbjct: 173 KNQMEPERCRIQTEFNQLRNILDRVEQ---RELKKLEQEEKKGLRIIEEAENDLVHQTQS 229
Query: 235 LALVISELEGKAQQPAAELMQDTRDFLNRYPRKKFW-VGKPIARVVKKKTGEFSDKLLSL 293
L +IS+LE + Q EL+QD D R +FW + KP A K ++ + L +
Sbjct: 230 LRELISDLERRCQGSTMELLQDVSDVTE---RSEFWTLRKPEALPTKLRSMFRAPDLKRM 286
Query: 294 QRGLREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSA-YLHPQQFD 352
R RE L D++ V VTL+P +A+ L L+++ + V + S + +D
Sbjct: 287 LRVCRE-----LTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYD 341
Query: 353 CEPGVLGSKGFTWGKVYWEVEVERE 377
C VLGS+ F+ GK YWEV+V ++
Sbjct: 342 C--SVLGSQHFSSGKHYWEVDVAKK 364
Score = 46.2 bits (108), Expect = 8e-05
Identities = 28/76 (36%), Positives = 41/76 (53%), Gaps = 5/76 (6%)
Query: 455 RPEDGVWALRLSSSG---IWANTSPEAELFPALRPRRVGIALDYEGGTVTFTNAESQEL- 510
+P+ G W + L + + ++SP L + PRRVG+ LDYE GTV+F N +
Sbjct: 396 QPQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFP 455
Query: 511 IYTFTA-TFTRRLVPF 525
IYTF+ F L P+
Sbjct: 456 IYTFSKYYFPTTLCPY 471
>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
Length = 516
Score = 179 bits (453), Expect = 7e-45
Identities = 127/385 (32%), Positives = 199/385 (51%), Gaps = 32/385 (8%)
Query: 3 TSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTT-----DVRPISGSRPVCPLCK 57
TS L + EEVTC ICL+ L +P++IDCGH FC++C T V G R CP+C+
Sbjct: 30 TSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERS-CPVCQ 88
Query: 58 KPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDG 117
++ N+RP LA++V + + + G+Q A LC H EKL +C++DG
Sbjct: 89 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQ--------LKAVLCADHGEKLQLFCQEDG 140
Query: 118 KLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAA 177
K++C +C S+EHR H L+E+ AQ ++EK L L+ + + + A +
Sbjct: 141 KVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSW 200
Query: 178 LKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGR---EKFKSRGVGELAR 234
+++ +R I EF Q L E+ +L KLEQE +G E+ ++ V +
Sbjct: 201 KNQMEPERCRIQTEFNQLRNILDRVEQ---RELKKLEQEEKKGLRIIEEAENDLVHQTQS 257
Query: 235 LALVISELEGKAQQPAAELMQDTRDFLNRYPRKKFW-VGKPIARVVKKKTGEFSDKLLSL 293
L +IS+LE + Q EL+QD D R +FW + KP A K ++ + L +
Sbjct: 258 LRELISDLERRCQGSTMELLQDVSDVTE---RSEFWTLRKPEALPTKLRSMFRAPDLKRM 314
Query: 294 QRGLREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSA-YLHPQQFD 352
R RE L D++ V VTL+P +A+ L L+++ + V + S + +D
Sbjct: 315 LRVCRE-----LTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYD 369
Query: 353 CEPGVLGSKGFTWGKVYWEVEVERE 377
C VLGS+ F+ GK YWEV+V ++
Sbjct: 370 C--SVLGSQHFSSGKHYWEVDVAKK 392
Score = 46.2 bits (108), Expect = 8e-05
Identities = 28/76 (36%), Positives = 41/76 (53%), Gaps = 5/76 (6%)
Query: 455 RPEDGVWALRLSSSG---IWANTSPEAELFPALRPRRVGIALDYEGGTVTFTNAESQEL- 510
+P+ G W + L + + ++SP L + PRRVG+ LDYE GTV+F N +
Sbjct: 424 QPQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFP 483
Query: 511 IYTFTA-TFTRRLVPF 525
IYTF+ F L P+
Sbjct: 484 IYTFSKYYFPTTLCPY 499
>gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
sapiens]
Length = 493
Score = 167 bits (424), Expect = 2e-41
Identities = 146/536 (27%), Positives = 242/536 (45%), Gaps = 74/536 (13%)
Query: 4 SAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRP---ISGSRPVCPLCKKPF 60
S L +++EEVTC ICL+ L P+++DCGH FC++C T + CP+C+ +
Sbjct: 3 SGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISY 62
Query: 61 KKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL 120
+ ENIRP +A+LVE + +K+ E Q C RH EKL +C++DGK++
Sbjct: 63 QPENIRPNRHVANLVEKLREVKLSP---------EGQKVDHCARHGEKLLLFCQEDGKVI 113
Query: 121 CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKK 180
C +C S+EHR H E+ AQ ++ K+ L LR+ + + + +A + + +
Sbjct: 114 CWLCERSQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQ 173
Query: 181 LQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVIS 240
+Q + ++A+FEQ L E + L+ L K E+++ + ++ V + L +IS
Sbjct: 174 IQYDKTNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELIS 233
Query: 241 ELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLREF 300
+LE + Q EL+Q + R + + KP ++ + L + RE
Sbjct: 234 DLEHRLQGSVMELLQGVDGVIKR--TENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRE- 290
Query: 301 QGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTS---LYKSAYLHPQ---QFDCE 354
L D+ V VT+ P + S + +SED + V+ +Y + Q F+
Sbjct: 291 ----LTDVRRYWVDVTVAPNNISCAV-ISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYC 345
Query: 355 PGVLGSKGFTWGKVYWEVEVERE-GWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETD 413
G+LGS+ T GK YWEV+V ++ W G + + E+ E Y Y W
Sbjct: 346 TGILGSQSITSGKHYWEVDVSKKTAWILGVCAGFQPDAMCNIEKNE--NYQPKYGYW--- 400
Query: 414 EDEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWAN 473
++G+ E+GV S
Sbjct: 401 ------------------------VIGL---------------EEGVKCSAFQDSSFHTP 421
Query: 474 TSP-EAELFPALRPRRVGIALDYEGGTVTFTNAESQE-LIYTFT-ATFTRRLVPFL 526
+ P L + P RVG+ LDYE TV+F N + LIY F+ +F++ + P+L
Sbjct: 422 SVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPYL 477
>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
sapiens]
Length = 500
Score = 166 bits (420), Expect = 5e-41
Identities = 160/573 (27%), Positives = 246/573 (42%), Gaps = 126/573 (21%)
Query: 10 LEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPFKKENIRPVW 69
++EE+TC ICLDY +DPV+I+CGH FCR C G CP C+ P +RP W
Sbjct: 6 IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNW 65
Query: 70 QLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLLCVMCRESRE 129
LA L E +R R+ G V LC RH E L +CEDD + +C++CRES+E
Sbjct: 66 ALARLTEKTQR------RRLGPV-----PPGLCGRHWEPLRLFCEDDQRPVCLVCRESQE 114
Query: 130 HRPHTAVLMEKAAQPHREKILN-HLSTLRRDRDKIQGFQAKGEADILAALK--------- 179
H+ H +++A + +R + H+ +R ++ + +K E +L + +
Sbjct: 115 HQTHAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKV 174
Query: 180 ----------------KLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREK 223
K++ QR I EF + H FL E E+ L++L K E+E + +
Sbjct: 175 MHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNE 234
Query: 224 FKSRGVGELARLALVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKT 283
+ +A L +I E+ K+Q P EL+Q+ ++ L R + VK KT
Sbjct: 235 NTLKLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLT---RSEIQDVNYSLEAVKVKT 291
Query: 284 GEFSDKLLSLQRGLREFQ-----------GKLLRDLEYKTVSVTLDPQSASGYLQLSEDW 332
++ ++ L+ FQ KL+ E + V T SAS + S W
Sbjct: 292 ---VCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNT---ASASSWPVFSSAW 345
Query: 333 KCVT-YTSLYKSAYLHPQQFDCEPGVLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEE 391
+ + K+A++ ++F P VLG FT GK YWEVE
Sbjct: 346 NYFAGWRNPQKTAFV--ERFQHLPCVLGKNVFTSGKHYWEVE------------------ 385
Query: 392 GEEEEEEEEAGYGDGYDDWETDEDEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGD 451
D E ++G V ++G+ D K D
Sbjct: 386 -------------------SRDSLEVAVG------------VCREDVMGIT-DRSKMSPD 413
Query: 452 LSLRPEDGVWALRLSSSGIW-----ANTSPEAELFPALRPRRVGIALDYEGGTVTFTNAE 506
+ + WA+ S++G W T + E PAL RVG+ LD G V+F +A
Sbjct: 414 VGI------WAIYWSAAGYWPLIGFPGTPTQQE--PAL--HRVGVYLDRGTGNVSFYSAV 463
Query: 507 SQELIYTFTATFTRRLVPFLWLKWPGTRLLLRP 539
++TF+ + RL PF WL P L++ P
Sbjct: 464 DGVHLHTFSCSSVSRLRPFFWLS-PLASLVIPP 495
>gi|117938316 tripartite motif-containing 22 [Homo sapiens]
Length = 498
Score = 160 bits (405), Expect = 3e-39
Identities = 108/369 (29%), Positives = 186/369 (50%), Gaps = 20/369 (5%)
Query: 10 LEEEVTCSICLDYLRDPVTIDCGHVFCRSCTT----DVRPISGSRPVCPLCKKPFKKENI 65
+E+EVTC ICL+ L +P+++DCGH FC++C T + IS CP+C+ F+ N+
Sbjct: 9 IEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNL 68
Query: 66 RPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLLCVMCR 125
RP LA++VE ++ +K+ +E Q +CE H +KL +C++DGK++C +C
Sbjct: 69 RPNRHLANIVERVKEVKMSP--------QEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120
Query: 126 ESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKKLQDQR 185
S+EH+ H + + + +EK+ L L ++ + + + + A +Q +R
Sbjct: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180
Query: 186 QYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVISELEGK 245
Q I+ F + L E+ L++L + E + + + V + + +IS+L+ +
Sbjct: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240
Query: 246 AQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLREFQGKLL 305
+ + E++QD D + R + W K V KK F LS G+ + K L
Sbjct: 241 LRGSSVEMLQDVIDVMK---RSESWTLKKPKSVSKKLKSVFRVPDLS---GMLQVL-KEL 293
Query: 306 RDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPGVLGSKGFTW 365
D++Y V V L+P SA+ + +S D + V +P F GV G + F+
Sbjct: 294 TDVQYYWVDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAF-GVFGCQYFSS 352
Query: 366 GKVYWEVEV 374
GK YWEV+V
Sbjct: 353 GKYYWEVDV 361
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/80 (33%), Positives = 44/80 (55%), Gaps = 9/80 (11%)
Query: 455 RPEDGVWALRLSSSGIW------ANTSPEA-ELFPALRPRRVGIALDYEGGTVTFTNAES 507
RP+ G W + L ++ + +++ P+ LF A+ P R+G+ LDYE G V+F N +
Sbjct: 402 RPQYGYWVIGLQNTCEYNAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTN 461
Query: 508 Q-ELIYTFT-ATFTRRLVPF 525
LIY F+ F+R P+
Sbjct: 462 HGALIYKFSGCRFSRPAYPY 481
>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
Length = 488
Score = 160 bits (405), Expect = 3e-39
Identities = 147/538 (27%), Positives = 247/538 (45%), Gaps = 91/538 (16%)
Query: 7 LRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTT----DVRPISGSRPVCPLCKKPFKK 62
L +++EEVTC ICL+ L +P+++DCGH CR+C T + G + CP+C +
Sbjct: 6 LLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSF 65
Query: 63 ENIRPVWQLASLVENIERLKV--DKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL 120
E+++ LA++VE ++ +K+ D G++ LC+ H EKL +C++D K++
Sbjct: 66 EHLQANQHLANIVERLKEVKLSPDNGKK----------RDLCDHHGEKLLLFCKEDRKVI 115
Query: 121 CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKK 180
C +C S+EHR H VL E+ + +EK+ L L+++ ++ + +A + + +
Sbjct: 116 CWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQ 175
Query: 181 LQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVIS 240
+Q +RQ I EF+Q L E+ L++L + E++ + + + V + + +IS
Sbjct: 176 VQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELIS 235
Query: 241 ELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLREF 300
++E ++Q EL+QD + + W K V KK F LS R L+ F
Sbjct: 236 DVECRSQWSTMELLQDMSGIMKW---SEIWRLKKPKMVSKKLKTVFHAPDLS--RMLQMF 290
Query: 301 QGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDC-EPGVLG 359
+ L + V VTL+ + + L LSED + V ++ F C GVLG
Sbjct: 291 RE--LTAVRCYWVDVTLNSVNLNLNLVLSEDQRQVISVPIWP--------FQCYNYGVLG 340
Query: 360 SKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDEES- 418
S+ F+ GK Y WE D +++
Sbjct: 341 SQYFSSGKHY----------------------------------------WEVDVSKKTA 360
Query: 419 --LGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSS---GIWA- 472
LG + V+ C R ++ K RP G W + L + G++
Sbjct: 361 WILGVYCRTYSRHMKYVVRRC---ANRQNLYTK----YRPLFGYWVIGLQNKCKYGVFEE 413
Query: 473 --NTSPEA-ELFPALRPRRVGIALDYEGGTVTFTNAESQ-ELIYTFT-ATFTRRLVPF 525
++ PE L A+ P RVG+ LDYE G V+F N S LIY F+ F++ + P+
Sbjct: 414 SLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPY 471
>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
Length = 488
Score = 160 bits (405), Expect = 3e-39
Identities = 147/538 (27%), Positives = 247/538 (45%), Gaps = 91/538 (16%)
Query: 7 LRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTT----DVRPISGSRPVCPLCKKPFKK 62
L +++EEVTC ICL+ L +P+++DCGH CR+C T + G + CP+C +
Sbjct: 6 LLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSF 65
Query: 63 ENIRPVWQLASLVENIERLKV--DKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL 120
E+++ LA++VE ++ +K+ D G++ LC+ H EKL +C++D K++
Sbjct: 66 EHLQANQHLANIVERLKEVKLSPDNGKK----------RDLCDHHGEKLLLFCKEDRKVI 115
Query: 121 CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKK 180
C +C S+EHR H VL E+ + +EK+ L L+++ ++ + +A + + +
Sbjct: 116 CWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQ 175
Query: 181 LQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVIS 240
+Q +RQ I EF+Q L E+ L++L + E++ + + + V + + +IS
Sbjct: 176 VQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELIS 235
Query: 241 ELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLREF 300
++E ++Q EL+QD + + W K V KK F LS R L+ F
Sbjct: 236 DVECRSQWSTMELLQDMSGIMKW---SEIWRLKKPKMVSKKLKTVFHAPDLS--RMLQMF 290
Query: 301 QGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDC-EPGVLG 359
+ L + V VTL+ + + L LSED + V ++ F C GVLG
Sbjct: 291 RE--LTAVRCYWVDVTLNSVNLNLNLVLSEDQRQVISVPIWP--------FQCYNYGVLG 340
Query: 360 SKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDEES- 418
S+ F+ GK Y WE D +++
Sbjct: 341 SQYFSSGKHY----------------------------------------WEVDVSKKTA 360
Query: 419 --LGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSS---GIWA- 472
LG + V+ C R ++ K RP G W + L + G++
Sbjct: 361 WILGVYCRTYSRHMKYVVRRC---ANRQNLYTK----YRPLFGYWVIGLQNKCKYGVFEE 413
Query: 473 --NTSPEA-ELFPALRPRRVGIALDYEGGTVTFTNAESQ-ELIYTFT-ATFTRRLVPF 525
++ PE L A+ P RVG+ LDYE G V+F N S LIY F+ F++ + P+
Sbjct: 414 SLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPY 471
>gi|51477690 tripartite motif-containing 6 and tripartite
motif-containing 34 [Homo sapiens]
Length = 842
Score = 160 bits (405), Expect = 3e-39
Identities = 147/538 (27%), Positives = 247/538 (45%), Gaps = 91/538 (16%)
Query: 7 LRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTT----DVRPISGSRPVCPLCKKPFKK 62
L +++EEVTC ICL+ L +P+++DCGH CR+C T + G + CP+C +
Sbjct: 360 LLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSF 419
Query: 63 ENIRPVWQLASLVENIERLKV--DKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL 120
E+++ LA++VE ++ +K+ D G++ LC+ H EKL +C++D K++
Sbjct: 420 EHLQANQHLANIVERLKEVKLSPDNGKK----------RDLCDHHGEKLLLFCKEDRKVI 469
Query: 121 CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKK 180
C +C S+EHR H VL E+ + +EK+ L L+++ ++ + +A + + +
Sbjct: 470 CWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQ 529
Query: 181 LQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVIS 240
+Q +RQ I EF+Q L E+ L++L + E++ + + + V + + +IS
Sbjct: 530 VQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELIS 589
Query: 241 ELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRGLREF 300
++E ++Q EL+QD + + W K V KK F LS R L+ F
Sbjct: 590 DVECRSQWSTMELLQDMSGIMKW---SEIWRLKKPKMVSKKLKTVFHAPDLS--RMLQMF 644
Query: 301 QGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDC-EPGVLG 359
+ L + V VTL+ + + L LSED + V ++ F C GVLG
Sbjct: 645 RE--LTAVRCYWVDVTLNSVNLNLNLVLSEDQRQVISVPIWP--------FQCYNYGVLG 694
Query: 360 SKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDEES- 418
S+ F+ GK Y WE D +++
Sbjct: 695 SQYFSSGKHY----------------------------------------WEVDVSKKTA 714
Query: 419 --LGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSS---GIWA- 472
LG + V+ C R ++ K RP G W + L + G++
Sbjct: 715 WILGVYCRTYSRHMKYVVRRC---ANRQNLYTK----YRPLFGYWVIGLQNKCKYGVFEE 767
Query: 473 --NTSPEA-ELFPALRPRRVGIALDYEGGTVTFTNAESQ-ELIYTFT-ATFTRRLVPF 525
++ PE L A+ P RVG+ LDYE G V+F N S LIY F+ F++ + P+
Sbjct: 768 SLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPY 825
Score = 149 bits (377), Expect = 5e-36
Identities = 101/306 (33%), Positives = 156/306 (50%), Gaps = 24/306 (7%)
Query: 3 TSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTT-----DVRPISGSRPVCPLCK 57
TS L + EEVTC ICL+ L +P++IDCGH FC++C T V G R CP+C+
Sbjct: 30 TSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERS-CPVCQ 88
Query: 58 KPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDG 117
++ N+RP LA++V + + + G+Q A LC H EKL +C++DG
Sbjct: 89 TSYQPGNLRPNRHLANIVRRLREVVLGPGKQ--------LKAVLCADHGEKLQLFCQEDG 140
Query: 118 KLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAA 177
K++C +C S+EHR H L+E+ AQ ++EK L L+ + + + A +
Sbjct: 141 KVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSW 200
Query: 178 LKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGR---EKFKSRGVGELAR 234
+++ +R I EF Q L E+ +L KLEQE +G E+ ++ V +
Sbjct: 201 KNQMEPERCRIQTEFNQLRNILDRVEQ---RELKKLEQEEKKGLRIIEEAENDLVHQTQS 257
Query: 235 LALVISELEGKAQQPAAELMQDTRDFLNRYPRKKFW-VGKPIARVVKKKTGEFSDKLLSL 293
L +IS+LE + Q EL+QD D R +FW + KP A K ++ + L +
Sbjct: 258 LRELISDLERRCQGSTMELLQDVSDVTE---RSEFWTLRKPEALPTKLRSMFRAPDLKRM 314
Query: 294 QRGLRE 299
R RE
Sbjct: 315 LRVCRE 320
>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
Length = 468
Score = 154 bits (388), Expect = 3e-37
Identities = 147/537 (27%), Positives = 229/537 (42%), Gaps = 107/537 (19%)
Query: 1 MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKK-- 58
M+T+ + +L EE+TC ICLDY PVT +CGH FC C + CP C +
Sbjct: 1 MSTADLMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEHNTPLSCPECWRTL 60
Query: 59 --PFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDD 116
P + N R + +LAS+ + + + G R AK E
Sbjct: 61 EGPHFQSNER-LGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALSDD--------EQG 111
Query: 117 GKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILA 176
G ++ H + L +A + HREK+ L+ LR R + Q + +
Sbjct: 112 GSAFV-----AQSHGANRVHLSSEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKL 166
Query: 177 ALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVG---ELA 233
++ + +Q +V+E+ + HQFL+E E+ QL LEQE E K ++ + ++
Sbjct: 167 CQEETKTCKQVVVSEYMKMHQFLKEEEQL---QLQLLEQEEKENMRKLRNNEIKLTQQIR 223
Query: 234 RLALVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSL 293
L+ +I+++E +Q A E +++ R L R + + + E + LSL
Sbjct: 224 SLSKMIAQIESSSQSSAFESLEEVRGALER------------SEPLLLQCPEATTTELSL 271
Query: 294 QR--GLREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQF 351
R G++E K + +TLDP +A+ YL LSED K V Y + +P++F
Sbjct: 272 CRITGMKEMLRKF-------STEITLDPATANAYLVLSEDLKSVKYGGSRQQLPDNPERF 324
Query: 352 DCEPGVLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWE 411
D VLG++ FT G+ YWEVEV G++ E WE
Sbjct: 325 DQSATVLGTQIFTSGRHYWEVEV-----------GNKTE-------------------WE 354
Query: 412 TDEDEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPED--GVWALRLSSS- 468
VG+ +DSV RKG+L P D + L++
Sbjct: 355 ---------------------------VGICKDSVSRKGNLPKPPGDLFSLIGLKIGDDY 387
Query: 469 GIWANTSPEAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTF-TATFTRRLVP 524
+W +SP +VG+ LDYE G + F N + LIY+F A+F L P
Sbjct: 388 SLWV-SSPLKGQHVREPVCKVGVFLDYESGHIAFYNGTDESLIYSFPQASFQEALRP 443
>gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]
Length = 500
Score = 147 bits (372), Expect = 2e-35
Identities = 136/526 (25%), Positives = 221/526 (42%), Gaps = 85/526 (16%)
Query: 7 LRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPVCPLCKKPFKKENIR 66
++ + E+ C +C D+ RDP+ + CGH FC +C D + CP CK + N
Sbjct: 32 IQDITMELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETFCPECKMLCQYNNCT 91
Query: 67 PVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLLCVMCRE 126
L LVE I++L + KG C H E L + + DGKL+C C++
Sbjct: 92 FNPVLDKLVEKIKKLPLLKGHPQ------------CPEHGENLKLFSKPDGKLICFQCKD 139
Query: 127 SREHRPHTAVLMEKAAQPH--REKILNHLSTLRRDRDKIQGFQAKGEADILAALKKLQDQ 184
+R + ++ + H E++ L ++Q + + I A +
Sbjct: 140 ARLSVGQSKEFLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHL 199
Query: 185 RQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLA--LVISEL 242
+Q++ EF + HQFL +E+ +L +L + + L E E S+ + E LA +++S
Sbjct: 200 QQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQ-LQEQCLLAKDMLVSIQ 258
Query: 243 EGKAQQPAAELMQDTRDFLNRYPR--KKFWVGKPIARVVKKKTGEFSDKLLSLQRGLREF 300
QQ + + ++D L+ + K + I+R K G++ + + RE
Sbjct: 259 AKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISR--KLNLGQYKGPIQYMV--WREM 314
Query: 301 QGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPGVLGS 360
Q L L +TLDP++A L LS+ V + + K P++FD VLGS
Sbjct: 315 QDTLCPGLS----PLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGS 370
Query: 361 KGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDEESLG 420
+ G+ G WE + +++
Sbjct: 371 R----------------------------------------GFTSGKWYWEVEVAKKT-- 388
Query: 421 DEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRL-SSSGIWANTSPEAE 479
VGV R+S+ RKG L PE G W LRL + + + A P
Sbjct: 389 ---------------KWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFS 433
Query: 480 LFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPF 525
L +VGI LDYEGG ++F NA++ IYTF+ TF +L P+
Sbjct: 434 LTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPY 479
>gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo
sapiens]
Length = 326
Score = 147 bits (370), Expect = 3e-35
Identities = 82/263 (31%), Positives = 140/263 (53%), Gaps = 12/263 (4%)
Query: 4 SAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRP---ISGSRPVCPLCKKPF 60
S L +++EEVTC ICL+ L P+++DCGH FC++C T + CP+C+ +
Sbjct: 3 SGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISY 62
Query: 61 KKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL 120
+ ENIRP +A++VE + +K+ E Q C RH EKL +C++DGK++
Sbjct: 63 QPENIRPNRHVANIVEKLREVKLSP---------EGQKVDHCARHGEKLLLFCQEDGKVI 113
Query: 121 CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKK 180
C +C S+EHR H L E+ AQ ++ K+ L LR+ + + + +A + + +
Sbjct: 114 CWLCERSQEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQ 173
Query: 181 LQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVIS 240
+Q + ++A+FEQ L E + L+ L K E+++ + ++ V + L +IS
Sbjct: 174 IQYDKTNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELIS 233
Query: 241 ELEGKAQQPAAELMQDTRDFLNR 263
+LE + Q EL+Q + R
Sbjct: 234 DLEHRLQGSVMELLQGVDGVIKR 256
>gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo
sapiens]
Length = 347
Score = 147 bits (370), Expect = 3e-35
Identities = 82/263 (31%), Positives = 140/263 (53%), Gaps = 12/263 (4%)
Query: 4 SAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRP---ISGSRPVCPLCKKPF 60
S L +++EEVTC ICL+ L P+++DCGH FC++C T + CP+C+ +
Sbjct: 3 SGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISY 62
Query: 61 KKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLL 120
+ ENIRP +A++VE + +K+ E Q C RH EKL +C++DGK++
Sbjct: 63 QPENIRPNRHVANIVEKLREVKLSP---------EGQKVDHCARHGEKLLLFCQEDGKVI 113
Query: 121 CVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILAALKK 180
C +C S+EHR H L E+ AQ ++ K+ L LR+ + + + +A + + +
Sbjct: 114 CWLCERSQEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQ 173
Query: 181 LQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLALVIS 240
+Q + ++A+FEQ L E + L+ L K E+++ + ++ V + L +IS
Sbjct: 174 IQYDKTNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELIS 233
Query: 241 ELEGKAQQPAAELMQDTRDFLNR 263
+LE + Q EL+Q + R
Sbjct: 234 DLEHRLQGSVMELLQGVDGVIKR 256
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,069,002
Number of Sequences: 37866
Number of extensions: 1257865
Number of successful extensions: 43361
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 911
Number of HSP's successfully gapped in prelim test: 605
Number of HSP's that attempted gapping in prelim test: 13257
Number of HSP's gapped (non-prelim): 13472
length of query: 539
length of database: 18,247,518
effective HSP length: 107
effective length of query: 432
effective length of database: 14,195,856
effective search space: 6132609792
effective search space used: 6132609792
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.