Search of human proteins with 4506175

Search of human proteins with 4506175

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a
[Homo sapiens]
         (435 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [H...   897   0.0  
gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b [...   852   0.0  
gi|157805480 pregnancy specific beta-1-glycoprotein 7 precursor ...   768   0.0  
gi|109240546 pregnancy specific beta-1-glycoprotein 3 [Homo sapi...   763   0.0  
gi|42560235 pregnancy specific beta-1-glycoprotein 4 isoform 1 [...   759   0.0  
gi|156616284 pregnancy specific beta-1-glycoprotein 9 [Homo sapi...   753   0.0  
gi|194328710 pregnancy specific beta-1-glycoprotein 8 isoform b ...   749   0.0  
gi|51510887 pregnancy specific beta-1-glycoprotein 8 isoform a [...   748   0.0  
gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens]   741   0.0  
gi|194328712 pregnancy specific beta-1-glycoprotein 8 isoform c ...   503   e-142
gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1...   446   e-125
gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2 [...   442   e-124
gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo sapi...   440   e-123
gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo sapi...   361   e-100
gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo sapi...   361   e-100
gi|40255013 carcinoembryonic antigen-related cell adhesion molec...   290   1e-78
gi|21314600 carcinoembryonic antigen-related cell adhesion molec...   283   2e-76
gi|68161541 carcinoembryonic antigen-related cell adhesion molec...   282   4e-76
gi|19923195 carcinoembryonic antigen-related cell adhesion molec...   282   4e-76
gi|98986445 carcinoembryonic antigen-related cell adhesion molec...   282   4e-76
gi|5901930 carcinoembryonic antigen-related cell adhesion molecu...   241   9e-64
gi|164663826 pregnancy specific beta-1-glycoprotein 11 isoform 2...   233   3e-61
gi|164663824 pregnancy specific beta-1-glycoprotein 11 isoform 2...   233   3e-61
gi|52317156 carcinoembryonic antigen-related cell adhesion molec...   174   2e-43
gi|148612793 carcinoembryonic antigen-related cell adhesion mole...   174   2e-43
gi|121114300 carcinoembryonic antigen-related cell adhesion mole...   159   6e-39
gi|156564378 carcinoembryonic antigen-related cell adhesion mole...   141   1e-33
gi|156564393 carcinoembryonic antigen-related cell adhesion mole...   141   1e-33
gi|71143132 carcinoembryonic antigen-related cell adhesion molec...   132   5e-31
gi|85861202 carcinoembryonic antigen-related cell adhesion molec...   132   6e-31

>gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [Homo
           sapiens]
          Length = 435

 Score =  897 bits (2319), Expect = 0.0
 Identities = 435/435 (100%), Positives = 435/435 (100%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSYT 120
           NLTGYIWYKGQMTDLYHYITSYVVHGQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSYT
Sbjct: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSYT 120

Query: 121 LHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWL 180
           LHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWL
Sbjct: 121 LHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWL 180

Query: 181 LNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPM 240
           LNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPM
Sbjct: 181 LNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPM 240

Query: 241 PYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVT 300
           PYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVT
Sbjct: 241 PYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVT 300

Query: 301 RNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPP 360
           RNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPP
Sbjct: 301 RNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPP 360

Query: 361 AEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVSETASPQV 420
           AEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVSETASPQV
Sbjct: 361 AEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVSETASPQV 420

Query: 421 TYAGPNTWFQEILLL 435
           TYAGPNTWFQEILLL
Sbjct: 421 TYAGPNTWFQEILLL 435


>gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b
           [Homo sapiens]
          Length = 424

 Score =  852 bits (2202), Expect = 0.0
 Identities = 413/413 (100%), Positives = 413/413 (100%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSYT 120
           NLTGYIWYKGQMTDLYHYITSYVVHGQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSYT
Sbjct: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSYT 120

Query: 121 LHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWL 180
           LHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWL
Sbjct: 121 LHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWL 180

Query: 181 LNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPM 240
           LNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPM
Sbjct: 181 LNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPM 240

Query: 241 PYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVT 300
           PYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVT
Sbjct: 241 PYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVT 300

Query: 301 RNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPP 360
           RNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPP
Sbjct: 301 RNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPP 360

Query: 361 AEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVS 413
           AEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVS
Sbjct: 361 AEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVS 413



 Score =  119 bits (298), Expect = 5e-27
 Identities = 75/232 (32%), Positives = 117/232 (50%), Gaps = 15/232 (6%)

Query: 102 SNASLLIQNVTQEDAGSYTLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVM 161
           +N +L +  VT+  AG Y   I  R   +   +   T+ L  + P P I+ +NLNPRE  
Sbjct: 197 TNRTLYLFGVTKYIAGPYECEI--RNPVSASRSDPVTLNLLPKLPMPYITINNLNPREKK 254

Query: 162 EAVRLICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNP 221
           + +   C+P++ + +Y+W LNGQ+LP++ R++    NR L L  VT+   GPY+CEIR+ 
Sbjct: 255 DVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDR 314

Query: 222 VSASRSDPVTLNLL--PKLPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSL 279
               RS+PVTLN+L  P LP  Y +       E  D+  F        Y+  W +NG   
Sbjct: 315 YGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPPAEYS--WTING--- 369

Query: 280 PVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGP 331
                 K  +  + L +P +T N +G Y C +R+   G   +   +  + GP
Sbjct: 370 ------KFQLSGQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVSGP 415



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 44/199 (22%), Positives = 74/199 (37%), Gaps = 30/199 (15%)

Query: 252 EKKDVLAFTCEPKSRNYTYIWW---------------LNGQSL--PVSPRVKRPIENRIL 294
           E KDVL            YIW+               ++GQ +  P     +    N  L
Sbjct: 47  EGKDVLLLVHNLPQNLTGYIWYKGQMTDLYHYITSYVVHGQIIYGPAYSGRETVYSNASL 106

Query: 295 ILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLD---L 351
           ++ +VT+ + G Y   I  R  G         V    + P+   S +     E ++   L
Sbjct: 107 LIQNVTQEDAGSYTLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRL 166

Query: 352 SCFADSNPPAEYSWTING-------KFQLS--GQKLFIPQITTNHSGLYACSVRNSATGK 402
            C  ++ P A Y W +NG       + QLS   + L++  +T   +G Y C +RN  +  
Sbjct: 167 ICDPET-PDASYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSAS 225

Query: 403 EISKSMIVKVSETASPQVT 421
                 +  + +   P +T
Sbjct: 226 RSDPVTLNLLPKLPMPYIT 244


>gi|157805480 pregnancy specific beta-1-glycoprotein 7 precursor
           [Homo sapiens]
          Length = 419

 Score =  768 bits (1982), Expect = 0.0
 Identities = 373/419 (89%), Positives = 386/419 (92%), Gaps = 1/419 (0%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MGPLSAPPCTQHITWKGLLLTASLLNFWN PTTAQV IEA+PPKVSEGKDVLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQII-YGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
           NLTGYIWYKGQ+ DLYHY+TSY+V GQII YGPAYSGRETVYSNASLLIQNVTQED GSY
Sbjct: 61  NLTGYIWYKGQIRDLYHYVTSYIVDGQIIKYGPAYSGRETVYSNASLLIQNVTQEDTGSY 120

Query: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
           TLHIIKRGDGTGGVTG FT TLY ETPKPSISSSN NPRE  EAV L CDPETPDASYLW
Sbjct: 121 TLHIIKRGDGTGGVTGRFTFTLYLETPKPSISSSNFNPREATEAVILTCDPETPDASYLW 180

Query: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP 239
            +NGQ+LPMTH LQLS+TNRTLYLFGVT Y AGPYECEIRNPVSASRSDPVTLNLLPKLP
Sbjct: 181 WMNGQSLPMTHSLQLSETNRTLYLFGVTNYTAGPYECEIRNPVSASRSDPVTLNLLPKLP 240

Query: 240 MPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 299
            PYITINNLNPRE KDV  FTCEPKS NYTYIWWLNGQSLPVSPRVKR IENRILILPSV
Sbjct: 241 KPYITINNLNPRENKDVSTFTCEPKSENYTYIWWLNGQSLPVSPRVKRRIENRILILPSV 300

Query: 300 TRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNP 359
           TRNETGPYQCEIRDRYGGIRS+PVTLNVLYGPDLPRIYPSFTYY SG+NL LSCFADSNP
Sbjct: 301 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYHSGQNLYLSCFADSNP 360

Query: 360 PAEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVSETASP 418
           PA+YSWTINGKFQLSGQKL IPQITT HSGLYACSVRNSATGKE SKS+ V+VS+   P
Sbjct: 361 PAQYSWTINGKFQLSGQKLSIPQITTKHSGLYACSVRNSATGKESSKSVTVRVSDWTLP 419



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 49/211 (23%), Positives = 81/211 (38%), Gaps = 33/211 (15%)

Query: 243 ITINNLNPR--EKKDVLAFTCEPKSRNYTYIWW---------------LNGQSLPVSPRV 285
           +TI    P+  E KDVL            YIW+               ++GQ +   P  
Sbjct: 36  VTIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRDLYHYVTSYIVDGQIIKYGPAY 95

Query: 286 ---KRPIENRILILPSVTRNETGPYQCEI---RDRYGGIRSNPVTLNVLYGPDLPRIYPS 339
              +    N  L++ +VT+ +TG Y   I    D  GG+         L  P       +
Sbjct: 96  SGRETVYSNASLLIQNVTQEDTGSYTLHIIKRGDGTGGVTGRFTFTLYLETPKPSISSSN 155

Query: 340 FTYYRSGENLDLSCFADSNPPAEYSWTINGK-------FQLS--GQKLFIPQITTNHSGL 390
           F    + E + L+C  ++ P A Y W +NG+        QLS   + L++  +T   +G 
Sbjct: 156 FNPREATEAVILTCDPET-PDASYLWWMNGQSLPMTHSLQLSETNRTLYLFGVTNYTAGP 214

Query: 391 YACSVRNSATGKEISKSMIVKVSETASPQVT 421
           Y C +RN  +        +  + +   P +T
Sbjct: 215 YECEIRNPVSASRSDPVTLNLLPKLPKPYIT 245


>gi|109240546 pregnancy specific beta-1-glycoprotein 3 [Homo
           sapiens]
          Length = 428

 Score =  763 bits (1970), Expect = 0.0
 Identities = 374/414 (90%), Positives = 383/414 (92%), Gaps = 1/414 (0%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MGPLSAPPCTQ ITWKGLLLTA LLNFWNLPTTAQV IEA+P KVS+GKDVLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTQRITWKGLLLTALLLNFWNLPTTAQVTIEAEPTKVSKGKDVLLLVHNLPQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQII-YGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
           NL GYIWYKGQM DLYHYITSYVV GQII YGPAYSGRETVYSNASLLIQNVT+EDAGSY
Sbjct: 61  NLAGYIWYKGQMKDLYHYITSYVVDGQIIIYGPAYSGRETVYSNASLLIQNVTREDAGSY 120

Query: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
           TLHI+KRGDGT G TG+FT TLY ETPKPSISSSNL PRE MEAV L CDPETPDASYLW
Sbjct: 121 TLHIVKRGDGTRGETGHFTFTLYLETPKPSISSSNLYPREDMEAVSLTCDPETPDASYLW 180

Query: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP 239
            +NGQ+LPMTH LQLSK  RTL+LFGVTKY AGPYECEIRNPVSASRSDPVTLNLLPKLP
Sbjct: 181 WMNGQSLPMTHSLQLSKNKRTLFLFGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP 240

Query: 240 MPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 299
            PYITINNLNPRE KDVLAFTCEPKS NYTYIWWLNGQSLPVSPRVKRPIENRILILPSV
Sbjct: 241 KPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 300

Query: 300 TRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNP 359
           TRNETGPYQCEI+DRYGGIRS PVTLNVLYGPDLPRIYPSFTYY SGENL LSCFADSNP
Sbjct: 301 TRNETGPYQCEIQDRYGGIRSYPVTLNVLYGPDLPRIYPSFTYYHSGENLYLSCFADSNP 360

Query: 360 PAEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVS 413
           PAEYSWTINGKFQLSGQKLFIPQITT HSGLYACSVRNSATG E SKSM VKVS
Sbjct: 361 PAEYSWTINGKFQLSGQKLFIPQITTKHSGLYACSVRNSATGMESSKSMTVKVS 414



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 40/143 (27%), Positives = 60/143 (41%), Gaps = 13/143 (9%)

Query: 291 NRILILPSVTRNETGPYQCEIRDRYGGIRSNP--VTLNVLYGPDLPRIYPSFTYYRSG-E 347
           N  L++ +VTR + G Y   I  R  G R      T  +      P I  S  Y R   E
Sbjct: 104 NASLLIQNVTREDAGSYTLHIVKRGDGTRGETGHFTFTLYLETPKPSISSSNLYPREDME 163

Query: 348 NLDLSCFADSNPPAEYSWTINGK-------FQLSGQK--LFIPQITTNHSGLYACSVRNS 398
            + L+C  ++ P A Y W +NG+        QLS  K  LF+  +T   +G Y C +RN 
Sbjct: 164 AVSLTCDPET-PDASYLWWMNGQSLPMTHSLQLSKNKRTLFLFGVTKYTAGPYECEIRNP 222

Query: 399 ATGKEISKSMIVKVSETASPQVT 421
            +        +  + +   P +T
Sbjct: 223 VSASRSDPVTLNLLPKLPKPYIT 245


>gi|42560235 pregnancy specific beta-1-glycoprotein 4 isoform 1
           [Homo sapiens]
          Length = 419

 Score =  759 bits (1959), Expect = 0.0
 Identities = 372/419 (88%), Positives = 387/419 (92%), Gaps = 1/419 (0%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MGPLSAPPCTQ ITWKG+LLTASLLNFWN PTTAQV IEA+PPKVSEGKDVLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTQRITWKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQ-IIYGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
           NL GYIWYKGQMT LYHYITSYVV GQ IIYGPAYSGRE VYSNASLLIQNVTQEDAGSY
Sbjct: 61  NLAGYIWYKGQMTYLYHYITSYVVDGQRIIYGPAYSGRERVYSNASLLIQNVTQEDAGSY 120

Query: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
           TLHIIKR DGTGGVTG+FT TL+ ETPKPSISSSNLNPRE MEAV L CDP TP ASY W
Sbjct: 121 TLHIIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAMEAVILTCDPATPAASYQW 180

Query: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP 239
            +NGQ+LPMTHRLQLSKTNRTL++FGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKL 
Sbjct: 181 WMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLS 240

Query: 240 MPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 299
            PYITINNLNPRE KDVL FTCEPKS+NYTYIWWLNGQSLPVSPRVKRPIENRILILP+V
Sbjct: 241 KPYITINNLNPRENKDVLTFTCEPKSKNYTYIWWLNGQSLPVSPRVKRPIENRILILPNV 300

Query: 300 TRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNP 359
           TRNETGPYQCEIRDRYGGIRS+PVTLNVLYGPDLP IYPSFTYYRSGENL LSCFA+SNP
Sbjct: 301 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNP 360

Query: 360 PAEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVSETASP 418
            A+YSWTINGKFQLSGQKL IPQITT HSGLYACSVRNSATGKE SKS+ VKVS+   P
Sbjct: 361 RAQYSWTINGKFQLSGQKLSIPQITTKHSGLYACSVRNSATGKESSKSITVKVSDWILP 419



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 51/211 (24%), Positives = 80/211 (37%), Gaps = 33/211 (15%)

Query: 243 ITINNLNPR--EKKDVLAFTCEPKSRNYTYIWW---------------LNGQSLPVSPRV 285
           +TI    P+  E KDVL            YIW+               ++GQ +   P  
Sbjct: 36  VTIEAQPPKVSEGKDVLLLVHNLPQNLAGYIWYKGQMTYLYHYITSYVVDGQRIIYGPAY 95

Query: 286 ---KRPIENRILILPSVTRNETGPYQCEI---RDRYGGIRSNPVTLNVLYGPDLPRIYPS 339
              +R   N  L++ +VT+ + G Y   I   RD  GG+  +  T  +      P I  S
Sbjct: 96  SGRERVYSNASLLIQNVTQEDAGSYTLHIIKRRDGTGGVTGH-FTFTLHLETPKPSISSS 154

Query: 340 FTYYRSGENLDLSCFADSNPPAEYSWTING-------KFQLS--GQKLFIPQITTNHSGL 390
               R      +     + P A Y W +NG       + QLS   + LFI  +T   +G 
Sbjct: 155 NLNPREAMEAVILTCDPATPAASYQWWMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGP 214

Query: 391 YACSVRNSATGKEISKSMIVKVSETASPQVT 421
           Y C +RN  +        +  + + + P +T
Sbjct: 215 YECEIRNPVSASRSDPVTLNLLPKLSKPYIT 245


>gi|156616284 pregnancy specific beta-1-glycoprotein 9 [Homo
           sapiens]
          Length = 426

 Score =  753 bits (1944), Expect = 0.0
 Identities = 367/414 (88%), Positives = 382/414 (92%), Gaps = 1/414 (0%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MGPL AP CTQ ITWKGLLLTASLLNFWN PTTA+V IEA+PPKVSEGKDVLLLVHNLPQ
Sbjct: 1   MGPLPAPSCTQRITWKGLLLTASLLNFWNPPTTAEVTIEAQPPKVSEGKDVLLLVHNLPQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQII-YGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
           NL GY WYKG+MTDLYHYI SY+V G+II YGPAYSGRETVYSNASLLIQNVT++DAG+Y
Sbjct: 61  NLPGYFWYKGEMTDLYHYIISYIVDGKIIIYGPAYSGRETVYSNASLLIQNVTRKDAGTY 120

Query: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
           TLHIIKRGD T     +FT TLY ETPKP ISSSNLNPRE MEAVRLICDPET DASYLW
Sbjct: 121 TLHIIKRGDETREEIRHFTFTLYLETPKPYISSSNLNPREAMEAVRLICDPETLDASYLW 180

Query: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP 239
            +NGQ+LP+THRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP
Sbjct: 181 WMNGQSLPVTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP 240

Query: 240 MPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 299
           +PYITINNLNPRE KDVLAFTCEPKS NYTYIWWLNGQSLPVSP VKRPIENRILILPSV
Sbjct: 241 IPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPGVKRPIENRILILPSV 300

Query: 300 TRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNP 359
           TRNETGPYQCEIRDRYGG+RSNPV LNVLYGPDLPRIYPSFTYYRSGENLDLSCF +SNP
Sbjct: 301 TRNETGPYQCEIRDRYGGLRSNPVILNVLYGPDLPRIYPSFTYYRSGENLDLSCFTESNP 360

Query: 360 PAEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVS 413
           PAEY WTINGKFQ SGQKLFIPQIT NHSGLYACSV NSATGKEISKSM VKVS
Sbjct: 361 PAEYFWTINGKFQQSGQKLFIPQITRNHSGLYACSVHNSATGKEISKSMTVKVS 414



 Score = 32.7 bits (73), Expect = 0.66
 Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 13/143 (9%)

Query: 291 NRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLD 350
           N  L++ +VTR + G Y   I  R    R            + P+ Y S +     E ++
Sbjct: 104 NASLLIQNVTRKDAGTYTLHIIKRGDETREEIRHFTFTLYLETPKPYISSSNLNPREAME 163

Query: 351 ---LSCFADSNPPAEYSWTING-------KFQLS--GQKLFIPQITTNHSGLYACSVRNS 398
              L C  ++   A Y W +NG       + QLS   + L++  +T   +G Y C +RN 
Sbjct: 164 AVRLICDPETLD-ASYLWWMNGQSLPVTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNP 222

Query: 399 ATGKEISKSMIVKVSETASPQVT 421
            +        +  + +   P +T
Sbjct: 223 VSASRSDPVTLNLLPKLPIPYIT 245


>gi|194328710 pregnancy specific beta-1-glycoprotein 8 isoform b
           [Homo sapiens]
          Length = 419

 Score =  749 bits (1935), Expect = 0.0
 Identities = 369/419 (88%), Positives = 381/419 (90%), Gaps = 1/419 (0%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MG LSAPPCTQ ITWKGLLLTASLLNFWN PTTAQV IEA+P KVSEGKDVLLLVHNLPQ
Sbjct: 1   MGLLSAPPCTQRITWKGLLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQII-YGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
           NLTGYIWYKGQ+ DLYHYITSYVV GQII YGPAYSGRET+YSNASLLIQNVTQEDAGSY
Sbjct: 61  NLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETIYSNASLLIQNVTQEDAGSY 120

Query: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
           TLHII  GD   GVTG+FT TLY ETPKPSISSS LNPRE MEAV L CDPETPDASYLW
Sbjct: 121 TLHIIMGGDENRGVTGHFTFTLYLETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLW 180

Query: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP 239
            +NGQ+LPM+HRLQLS+TNRTL+L GVTKY AGPYECEIRNPVSASRSDP TLNLLPKLP
Sbjct: 181 WMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLLPKLP 240

Query: 240 MPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 299
            PYITINNL PRE KDVL FTCEPKS NYTYIWWLNGQSLPVSPRVKRPIENRILILPSV
Sbjct: 241 KPYITINNLKPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 300

Query: 300 TRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNP 359
           TRNETGPYQCEIRD+YGGIRS PVTLNVLYGPDLPRIYPSFTYYRSGE L LSC ADSNP
Sbjct: 301 TRNETGPYQCEIRDQYGGIRSYPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP 360

Query: 360 PAEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVSETASP 418
           PA+YSWTINGKFQLSGQKLFIPQITT HSGLYACSVRNSATGKE SKSM VKVS+   P
Sbjct: 361 PAQYSWTINGKFQLSGQKLFIPQITTKHSGLYACSVRNSATGKESSKSMTVKVSDWTLP 419



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 47/202 (23%), Positives = 78/202 (38%), Gaps = 35/202 (17%)

Query: 252 EKKDVLAFTCEPKSRNYTYIWW---------------LNGQSLPVSPRV---KRPIENRI 293
           E KDVL            YIW+               ++GQ +   P     +    N  
Sbjct: 47  EGKDVLLLVHNLPQNLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETIYSNAS 106

Query: 294 LILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSG-----EN 348
           L++ +VT+ + G Y   I    GG  +  VT +  +   L    PS +  +       E 
Sbjct: 107 LLIQNVTQEDAGSYTLHII--MGGDENRGVTGHFTFTLYLETPKPSISSSKLNPREAMEA 164

Query: 349 LDLSCFADSNPPAEYSWTING-------KFQLS--GQKLFIPQITTNHSGLYACSVRNSA 399
           + L+C  ++ P A Y W +NG       + QLS   + LF+  +T   +G Y C +RN  
Sbjct: 165 VSLTCDPET-PDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRNPV 223

Query: 400 TGKEISKSMIVKVSETASPQVT 421
           +        +  + +   P +T
Sbjct: 224 SASRSDPFTLNLLPKLPKPYIT 245


>gi|51510887 pregnancy specific beta-1-glycoprotein 8 isoform a
           [Homo sapiens]
          Length = 426

 Score =  748 bits (1931), Expect = 0.0
 Identities = 369/419 (88%), Positives = 380/419 (90%), Gaps = 1/419 (0%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MG LSAPPCTQ ITWKGLLLTASLLNFWN PTTAQV IEA+P KVSEGKDVLLLVHNLPQ
Sbjct: 1   MGLLSAPPCTQRITWKGLLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQII-YGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
           NLTGYIWYKGQ+ DLYHYITSYVV GQII YGPAYSGRET+YSNASLLIQNVTQEDAGSY
Sbjct: 61  NLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETIYSNASLLIQNVTQEDAGSY 120

Query: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
           TLHII  GD   GVTG+FT TLY ETPKPSISSS LNPRE MEAV L CDPETPDASYLW
Sbjct: 121 TLHIIMGGDENRGVTGHFTFTLYLETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLW 180

Query: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP 239
            +NGQ+LPM+HRLQLS+TNRTL+L GVTKY AGPYECEIRNPVSASRSDP TLNLLPKLP
Sbjct: 181 WMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLLPKLP 240

Query: 240 MPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 299
            PYITINNL PRE KDVL FTCEPKS NYTYIWWLNGQSLPVSPRVKRPIENRILILPSV
Sbjct: 241 KPYITINNLKPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 300

Query: 300 TRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNP 359
           TRNETGPYQCEIRD+YGGIRS PVTLNVLYGPDLPRIYPSFTYYRSGE L LSC ADSNP
Sbjct: 301 TRNETGPYQCEIRDQYGGIRSYPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP 360

Query: 360 PAEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVSETASP 418
           PA+YSWTINGKFQLSGQKLFIPQITT HSGLYACSVRNSATGKE SKSM VKVS    P
Sbjct: 361 PAQYSWTINGKFQLSGQKLFIPQITTKHSGLYACSVRNSATGKESSKSMTVKVSGKRIP 419



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 47/202 (23%), Positives = 78/202 (38%), Gaps = 35/202 (17%)

Query: 252 EKKDVLAFTCEPKSRNYTYIWW---------------LNGQSLPVSPRV---KRPIENRI 293
           E KDVL            YIW+               ++GQ +   P     +    N  
Sbjct: 47  EGKDVLLLVHNLPQNLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETIYSNAS 106

Query: 294 LILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSG-----EN 348
           L++ +VT+ + G Y   I    GG  +  VT +  +   L    PS +  +       E 
Sbjct: 107 LLIQNVTQEDAGSYTLHII--MGGDENRGVTGHFTFTLYLETPKPSISSSKLNPREAMEA 164

Query: 349 LDLSCFADSNPPAEYSWTING-------KFQLS--GQKLFIPQITTNHSGLYACSVRNSA 399
           + L+C  ++ P A Y W +NG       + QLS   + LF+  +T   +G Y C +RN  
Sbjct: 165 VSLTCDPET-PDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRNPV 223

Query: 400 TGKEISKSMIVKVSETASPQVT 421
           +        +  + +   P +T
Sbjct: 224 SASRSDPFTLNLLPKLPKPYIT 245


>gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens]
          Length = 426

 Score =  741 bits (1913), Expect = 0.0
 Identities = 365/414 (88%), Positives = 377/414 (91%), Gaps = 1/414 (0%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MG LSAPPCTQ I WKGLLLTASLLNFWNLPTTAQV IEA+P KVSEGKDVLLLVHNLPQ
Sbjct: 1   MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQII-YGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
           NLTGYIWYKGQM DLYHYITSYVV G+II YGPAYSGRET YSNASLLIQNVT+EDAGSY
Sbjct: 61  NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY 120

Query: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
           TLHIIK  DGT GVTG FT TL+ ETPKPSISSSNLNPRE MEAV L CDPETPDASYLW
Sbjct: 121 TLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLW 180

Query: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP 239
            +NGQ+LPMTH L+LS+TNRTL+L GVTKY AGPYECEIRNPVSASRSDPVTLNLLPKLP
Sbjct: 181 WMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP 240

Query: 240 MPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 299
            PYITINNLNPRE KDVL FTCEPKS NYTYIWWLNGQSLPVSPRVKRPIENRILILPSV
Sbjct: 241 KPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 300

Query: 300 TRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNP 359
           TRNETGPYQCEIRDRYGGIRS+PVTLNVLYGPDLPRIYPSFTYYRSGE L LSC ADSNP
Sbjct: 301 TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNP 360

Query: 360 PAEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVS 413
           PA+YSWTIN KFQL GQKLFI  ITT HSGLY CSVRNSATGKE SKSM V+VS
Sbjct: 361 PAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVS 414



 Score = 38.1 bits (87), Expect = 0.016
 Identities = 32/143 (22%), Positives = 56/143 (39%), Gaps = 13/143 (9%)

Query: 291 NRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLD 350
           N  L++ +VTR + G Y   I     G R            + P+   S +     E ++
Sbjct: 104 NASLLIQNVTREDAGSYTLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETME 163

Query: 351 ---LSCFADSNPPAEYSWTING---------KFQLSGQKLFIPQITTNHSGLYACSVRNS 398
              L+C  ++ P A Y W +NG         K   + + LF+  +T   +G Y C +RN 
Sbjct: 164 AVSLTCDPET-PDASYLWWMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNP 222

Query: 399 ATGKEISKSMIVKVSETASPQVT 421
            +        +  + +   P +T
Sbjct: 223 VSASRSDPVTLNLLPKLPKPYIT 245


>gi|194328712 pregnancy specific beta-1-glycoprotein 8 isoform c
           [Homo sapiens]
          Length = 297

 Score =  503 bits (1296), Expect = e-142
 Identities = 244/275 (88%), Positives = 252/275 (91%)

Query: 144 ETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYL 203
           ETPKPSISSS LNPRE MEAV L CDPETPDASYLW +NGQ+LPM+HRLQLS+TNRTL+L
Sbjct: 23  ETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSETNRTLFL 82

Query: 204 FGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPMPYITINNLNPREKKDVLAFTCEP 263
            GVTKY AGPYECEIRNPVSASRSDP TLNLLPKLP PYITINNL PRE KDVL FTCEP
Sbjct: 83  LGVTKYTAGPYECEIRNPVSASRSDPFTLNLLPKLPKPYITINNLKPRENKDVLNFTCEP 142

Query: 264 KSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPV 323
           KS NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRD+YGGIRS PV
Sbjct: 143 KSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPV 202

Query: 324 TLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPPAEYSWTINGKFQLSGQKLFIPQI 383
           TLNVLYGPDLPRIYPSFTYYRSGE L LSC ADSNPPA+YSWTINGKFQLSGQKLFIPQI
Sbjct: 203 TLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINGKFQLSGQKLFIPQI 262

Query: 384 TTNHSGLYACSVRNSATGKEISKSMIVKVSETASP 418
           TT HSGLYACSVRNSATGKE SKSM VKVS+   P
Sbjct: 263 TTKHSGLYACSVRNSATGKESSKSMTVKVSDWTLP 297



 Score =  146 bits (368), Expect = 4e-35
 Identities = 104/325 (32%), Positives = 152/325 (46%), Gaps = 45/325 (13%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MG LSAPPCTQ ITWKGLLLT           T +  I +      E  + + L  +   
Sbjct: 1   MGLLSAPPCTQRITWKGLLLTVE---------TPKPSISSSKLNPREAMEAVSLTCDPET 51

Query: 61  NLTGYIWY-KGQMTDLYHYITSYVVHGQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
               Y+W+  GQ   + H +                  +   +N +L +  VT+  AG Y
Sbjct: 52  PDASYLWWMNGQSLPMSHRL------------------QLSETNRTLFLLGVTKYTAGPY 93

Query: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
              I  R   +   +  FT+ L  + PKP I+ +NL PRE  + +   C+P++ + +Y+W
Sbjct: 94  ECEI--RNPVSASRSDPFTLNLLPKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYIW 151

Query: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLL--PK 237
            LNGQ+LP++ R++    NR L L  VT+   GPY+CEIR+     RS PVTLN+L  P 
Sbjct: 152 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNVLYGPD 211

Query: 238 LPMPYITINNLNPREKKDVLAFTCEPKSR-NYTYIWWLNGQSLPVSPRVKRPIENRILIL 296
           LP  Y +       E   VL  +C   S     Y W +NG         K  +  + L +
Sbjct: 212 LPRIYPSFTYYRSGE---VLYLSCSADSNPPAQYSWTING---------KFQLSGQKLFI 259

Query: 297 PSVTRNETGPYQCEIRDRYGGIRSN 321
           P +T   +G Y C +R+   G  S+
Sbjct: 260 PQITTKHSGLYACSVRNSATGKESS 284



 Score =  123 bits (308), Expect = 4e-28
 Identities = 68/182 (37%), Positives = 102/182 (56%), Gaps = 15/182 (8%)

Query: 232 LNLLPKLPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIEN 291
           L L  + P P I+ + LNPRE  + ++ TC+P++ + +Y+WW+NGQSLP+S R++    N
Sbjct: 18  LLLTVETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSETN 77

Query: 292 RILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDL 351
           R L L  VT+   GPY+CEIR+     RS+P TLN+L  P LP+ Y +    +  EN D+
Sbjct: 78  RTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLL--PKLPKPYITINNLKPRENKDV 135

Query: 352 SCFADSNPPAE---YSWTING---------KFQLSGQKLFIPQITTNHSGLYACSVRNSA 399
             F    P +E   Y W +NG         K  +  + L +P +T N +G Y C +R+  
Sbjct: 136 LNFT-CEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQY 194

Query: 400 TG 401
            G
Sbjct: 195 GG 196



 Score = 32.7 bits (73), Expect = 0.66
 Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 10/84 (11%)

Query: 347 ENLDLSCFADSNPPAEYSWTING-------KFQLS--GQKLFIPQITTNHSGLYACSVRN 397
           E + L+C  ++ P A Y W +NG       + QLS   + LF+  +T   +G Y C +RN
Sbjct: 41  EAVSLTCDPET-PDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRN 99

Query: 398 SATGKEISKSMIVKVSETASPQVT 421
             +        +  + +   P +T
Sbjct: 100 PVSASRSDPFTLNLLPKLPKPYIT 123


>gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1
           [Homo sapiens]
          Length = 335

 Score =  446 bits (1148), Expect = e-125
 Identities = 232/337 (68%), Positives = 259/337 (76%), Gaps = 15/337 (4%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MGPLSAPPCT+HI WKGLLLTA LLNFWNLPTTAQV+IEA+PPKVSEGKDVLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTEHIKWKGLLLTALLLNFWNLPTTAQVMIEAQPPKVSEGKDVLLLVHNLPQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQII-YGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
           NLTGYIWYKGQ+ DLYHYITSYVV GQII YGPAYSGRETVYSNASLLIQNVT+EDAGSY
Sbjct: 61  NLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETVYSNASLLIQNVTREDAGSY 120

Query: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
           TLHIIKRGDGT GVTGYFT TLY ETPKPSISSSNLNPRE ME V L C+PETPDASYLW
Sbjct: 121 TLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETVILTCNPETPDASYLW 180

Query: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLL--PK 237
            +NGQ+LPMTHR+QLS+TNRTL+LFGVTKY AGPYECEI N  SASRSDPVTLNLL  P 
Sbjct: 181 WMNGQSLPMTHRMQLSETNRTLFLFGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPD 240

Query: 238 LPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILP 297
           LP  + ++ +    E  D+  F        Y+  W +NG         K  +  + L +P
Sbjct: 241 LPRIFPSVTSYYSGENLDLSCFANSNPPAQYS--WTING---------KFQLSGQKLFIP 289

Query: 298 SVTRNETGPYQCEIRDRYGGIRSN-PVTLNVLYGPDL 333
            +T    G Y C  R+   G  S+  +T+ V+  P L
Sbjct: 290 QITPKHNGLYACSARNSATGEESSTSLTIRVIAPPGL 326



 Score =  239 bits (610), Expect = 4e-63
 Identities = 119/218 (54%), Positives = 154/218 (70%), Gaps = 2/218 (0%)

Query: 197 TNRTLYLFGVTKYIAGPYECEIRNPVSASR--SDPVTLNLLPKLPMPYITINNLNPREKK 254
           +N +L +  VT+  AG Y   I      +R  +   T  L  + P P I+ +NLNPRE  
Sbjct: 103 SNASLLIQNVTREDAGSYTLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAM 162

Query: 255 DVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDR 314
           + +  TC P++ + +Y+WW+NGQSLP++ R++    NR L L  VT+   GPY+CEI + 
Sbjct: 163 ETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFLFGVTKYTAGPYECEIWNS 222

Query: 315 YGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPPAEYSWTINGKFQLS 374
               RS+PVTLN+L+GPDLPRI+PS T Y SGENLDLSCFA+SNPPA+YSWTINGKFQLS
Sbjct: 223 GSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDLSCFANSNPPAQYSWTINGKFQLS 282

Query: 375 GQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKV 412
           GQKLFIPQIT  H+GLYACS RNSATG+E S S+ ++V
Sbjct: 283 GQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRV 320


>gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2
           [Homo sapiens]
          Length = 326

 Score =  442 bits (1138), Expect = e-124
 Identities = 232/325 (71%), Positives = 252/325 (77%), Gaps = 16/325 (4%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MGPLSAPPCTQ ITWKG+LLTASLLNFWN PTTAQV IEA+PPKVSEGKDVLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTQRITWKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQ-IIYGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
           NL GYIWYKGQMT LYHYITSYVV GQ IIYGPAYSGRE VYSNASLLIQNVTQEDAGSY
Sbjct: 61  NLAGYIWYKGQMTYLYHYITSYVVDGQRIIYGPAYSGRERVYSNASLLIQNVTQEDAGSY 120

Query: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
           TLHIIKR DGTGGVTG+FT TL+ ETPKPSISSSNLNPRE MEAV L CDP TP ASY W
Sbjct: 121 TLHIIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAMEAVILTCDPATPAASYQW 180

Query: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLL--PK 237
            +NGQ+LPMTHRLQLSKTNRTL++FGVTKYIAGPYECEIRNPVSASRSDPVTLNLL  P 
Sbjct: 181 WMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLHGPD 240

Query: 238 LPMPYITINNLNPREKKDVLAFTCEPKSR-NYTYIWWLNGQSLPVSPRVKRPIENRILIL 296
           LP  Y +       E    L  +C  +S     Y W +NG         K  +  + L +
Sbjct: 241 LPSIYPSFTYYRSGEN---LYLSCFAESNPRAQYSWTING---------KFQLSGQKLSI 288

Query: 297 PSVTRNETGPYQCEIRDRYGGIRSN 321
           P +T   +G Y C +R+   G  S+
Sbjct: 289 PQITTKHSGLYACSVRNSATGKESS 313



 Score =  249 bits (636), Expect = 3e-66
 Identities = 128/224 (57%), Positives = 158/224 (70%), Gaps = 2/224 (0%)

Query: 197 TNRTLYLFGVTKYIAGPYECEI--RNPVSASRSDPVTLNLLPKLPMPYITINNLNPREKK 254
           +N +L +  VT+  AG Y   I  R   +   +   T  L  + P P I+ +NLNPRE  
Sbjct: 103 SNASLLIQNVTQEDAGSYTLHIIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAM 162

Query: 255 DVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDR 314
           + +  TC+P +   +Y WW+NGQSLP++ R++    NR L +  VT+   GPY+CEIR+ 
Sbjct: 163 EAVILTCDPATPAASYQWWMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNP 222

Query: 315 YGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPPAEYSWTINGKFQLS 374
               RS+PVTLN+L+GPDLP IYPSFTYYRSGENL LSCFA+SNP A+YSWTINGKFQLS
Sbjct: 223 VSASRSDPVTLNLLHGPDLPSIYPSFTYYRSGENLYLSCFAESNPRAQYSWTINGKFQLS 282

Query: 375 GQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVSETASP 418
           GQKL IPQITT HSGLYACSVRNSATGKE SKS+ VKVS+   P
Sbjct: 283 GQKLSIPQITTKHSGLYACSVRNSATGKESSKSITVKVSDWILP 326


>gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo
           sapiens]
          Length = 335

 Score =  440 bits (1132), Expect = e-123
 Identities = 229/323 (70%), Positives = 249/323 (77%), Gaps = 12/323 (3%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MGPLSAPPCT+HI WKGLL+TASLLNFWNLPTTAQV IEA+PPKVSEGKDVLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTEHIKWKGLLVTASLLNFWNLPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQII-YGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
           NLTGYIWYKGQ+ DLYHYITSYVV GQII YGPAYSGRET YSNASLLIQNVT+EDAGSY
Sbjct: 61  NLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY 120

Query: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
           TLHIIKRGDGT GVTGYFT TLY ETPKPSISSSNLNPRE ME V L CDPETPD SY W
Sbjct: 121 TLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETVILTCDPETPDTSYQW 180

Query: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP 239
            +NGQ+LPMTHR QLS+TNRTL+LFGVTKY AGPYECEIRN  SASRSDPVTLNLL    
Sbjct: 181 WMNGQSLPMTHRFQLSETNRTLFLFGVTKYTAGPYECEIRNSGSASRSDPVTLNLLHGPD 240

Query: 240 MPYITINNLNPREKKDVLAFTCEPKSR-NYTYIWWLNGQSLPVSPRVKRPIENRILILPS 298
           +P I  +  N R   D L  +C   S     Y W +NG         K     + L +P 
Sbjct: 241 LPRIHPSYTNYR-SGDNLYLSCFANSNPPAQYSWTING---------KFQQSGQNLFIPQ 290

Query: 299 VTRNETGPYQCEIRDRYGGIRSN 321
           +T   +G Y C +R+   G  S+
Sbjct: 291 ITTKHSGLYVCSVRNSATGEESS 313



 Score =  242 bits (617), Expect = 6e-64
 Identities = 122/219 (55%), Positives = 155/219 (70%), Gaps = 2/219 (0%)

Query: 197 TNRTLYLFGVTKYIAGPYECEIRNPVSASR--SDPVTLNLLPKLPMPYITINNLNPREKK 254
           +N +L +  VT+  AG Y   I      +R  +   T  L  + P P I+ +NLNPRE  
Sbjct: 103 SNASLLIQNVTREDAGSYTLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAM 162

Query: 255 DVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDR 314
           + +  TC+P++ + +Y WW+NGQSLP++ R +    NR L L  VT+   GPY+CEIR+ 
Sbjct: 163 ETVILTCDPETPDTSYQWWMNGQSLPMTHRFQLSETNRTLFLFGVTKYTAGPYECEIRNS 222

Query: 315 YGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPPAEYSWTINGKFQLS 374
               RS+PVTLN+L+GPDLPRI+PS+T YRSG+NL LSCFA+SNPPA+YSWTINGKFQ S
Sbjct: 223 GSASRSDPVTLNLLHGPDLPRIHPSYTNYRSGDNLYLSCFANSNPPAQYSWTINGKFQQS 282

Query: 375 GQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVS 413
           GQ LFIPQITT HSGLY CSVRNSATG+E S S+ VKVS
Sbjct: 283 GQNLFIPQITTKHSGLYVCSVRNSATGEESSTSLTVKVS 321


>gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo
           sapiens]
          Length = 335

 Score =  361 bits (927), Expect = e-100
 Identities = 193/325 (59%), Positives = 225/325 (69%), Gaps = 16/325 (4%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MGPLSAPPCTQHITWKGLLLTASLLNFWNLP TAQV IEA PPKVSEGKDVLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQI-IYGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
           NL GYIWYKGQ+ DLYHYITSYVV GQI IYGPAY+GRETVYSNASLLIQNVT+EDAGSY
Sbjct: 61  NLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSY 120

Query: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
           TLHIIKRGD T GVTGYFT  LY + PKP I+ +N  PRE  + +   C+P++ + +Y+W
Sbjct: 121 TLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIW 180

Query: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLL--PK 237
            LNGQ+LP++ R++    NR L L  VT+   GPYECEIR+     RSDPVTLN+L  P 
Sbjct: 181 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPD 240

Query: 238 LPMPYITINNLNPREKKDVLAFTCEPKSR-NYTYIWWLNGQSLPVSPRVKRPIENRILIL 296
           LP  Y +       E    L  +C  +S     Y W +NG         K     + L +
Sbjct: 241 LPSIYPSFTYYRSGEN---LYLSCFAESNPPAEYFWTING---------KFQQSGQKLSI 288

Query: 297 PSVTRNETGPYQCEIRDRYGGIRSN 321
           P +T    G Y C +R+   G  S+
Sbjct: 289 PQITTKHRGLYTCSVRNSATGKESS 313



 Score =  334 bits (857), Expect = 8e-92
 Identities = 168/219 (76%), Positives = 179/219 (81%), Gaps = 2/219 (0%)

Query: 197 TNRTLYLFGVTKYIAGPYECEI--RNPVSASRSDPVTLNLLPKLPMPYITINNLNPREKK 254
           +N +L +  VT+  AG Y   I  R   +   +   T NL  KLP PYITINN  PRE K
Sbjct: 103 SNASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENK 162

Query: 255 DVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDR 314
           DVLAFTCEPKS NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPY+CEIRDR
Sbjct: 163 DVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDR 222

Query: 315 YGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPPAEYSWTINGKFQLS 374
            GG+RS+PVTLNVLYGPDLP IYPSFTYYRSGENL LSCFA+SNPPAEY WTINGKFQ S
Sbjct: 223 DGGMRSDPVTLNVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQS 282

Query: 375 GQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVS 413
           GQKL IPQITT H GLY CSVRNSATGKE SKSM V+VS
Sbjct: 283 GQKLSIPQITTKHRGLYTCSVRNSATGKESSKSMTVEVS 321


>gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo
           sapiens]
          Length = 335

 Score =  361 bits (927), Expect = e-100
 Identities = 193/325 (59%), Positives = 225/325 (69%), Gaps = 16/325 (4%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MGPLSAPPCTQHITWKGLLLTASLLNFWNLP TAQV IEA PPKVSEGKDVLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQI-IYGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
           NL GYIWYKGQ+ DLYHYITSYVV GQI IYGPAY+GRETVYSNASLLIQNVT+EDAGSY
Sbjct: 61  NLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSY 120

Query: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
           TLHIIKRGD T GVTGYFT  LY + PKP I+ +N  PRE  + +   C+P++ + +Y+W
Sbjct: 121 TLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIW 180

Query: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLL--PK 237
            LNGQ+LP++ R++    NR L L  VT+   GPYECEIR+     RSDPVTLN+L  P 
Sbjct: 181 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPD 240

Query: 238 LPMPYITINNLNPREKKDVLAFTCEPKSR-NYTYIWWLNGQSLPVSPRVKRPIENRILIL 296
           LP  Y +       E    L  +C  +S     Y W +NG         K     + L +
Sbjct: 241 LPSIYPSFTYYRSGEN---LYLSCFAESNPPAEYFWTING---------KFQQSGQKLSI 288

Query: 297 PSVTRNETGPYQCEIRDRYGGIRSN 321
           P +T    G Y C +R+   G  S+
Sbjct: 289 PQITTKHRGLYTCSVRNSATGKESS 313



 Score =  334 bits (857), Expect = 8e-92
 Identities = 168/219 (76%), Positives = 179/219 (81%), Gaps = 2/219 (0%)

Query: 197 TNRTLYLFGVTKYIAGPYECEI--RNPVSASRSDPVTLNLLPKLPMPYITINNLNPREKK 254
           +N +L +  VT+  AG Y   I  R   +   +   T NL  KLP PYITINN  PRE K
Sbjct: 103 SNASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENK 162

Query: 255 DVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDR 314
           DVLAFTCEPKS NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPY+CEIRDR
Sbjct: 163 DVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDR 222

Query: 315 YGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPPAEYSWTINGKFQLS 374
            GG+RS+PVTLNVLYGPDLP IYPSFTYYRSGENL LSCFA+SNPPAEY WTINGKFQ S
Sbjct: 223 DGGMRSDPVTLNVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQS 282

Query: 375 GQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVS 413
           GQKL IPQITT H GLY CSVRNSATGKE SKSM V+VS
Sbjct: 283 GQKLSIPQITTKHRGLYTCSVRNSATGKESSKSMTVEVS 321


>gi|40255013 carcinoembryonic antigen-related cell adhesion molecule
           6 (non-specific cross reacting antigen) [Homo sapiens]
          Length = 344

 Score =  290 bits (743), Expect = 1e-78
 Identities = 163/332 (49%), Positives = 204/332 (61%), Gaps = 14/332 (4%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MGP SAPPC  H+ WK +LLTASLL FWN PTTA++ IE+ P  V+EGK+VLLL HNLPQ
Sbjct: 1   MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQ-IIYGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
           N  GY WYKG+  D    I  YV+  Q    GPAYSGRET+Y NASLLIQNVTQ D G Y
Sbjct: 61  NRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFY 120

Query: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
           TL +IK        TG F V  Y E PKPSISS+N NP E  +AV   C+PE  + +YLW
Sbjct: 121 TLQVIKSDLVNEEATGQFHV--YPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLW 178

Query: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP 239
            +NGQ+LP++ RLQLS  N TL L  V +  AG YECEI+NP SA+RSDPVTLN+L    
Sbjct: 179 WVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPD 238

Query: 240 MPYITINNLNPREKKDVLAFTCEPKSR-NYTYIWWLNGQSLPVSPRVKRPIENRILILPS 298
            P I+ +  N R  ++ L  +C   S     Y W++NG               + L +P+
Sbjct: 239 GPTISPSKANYRPGEN-LNLSCHAASNPPAQYSWFINGTFQQ---------STQELFIPN 288

Query: 299 VTRNETGPYQCEIRDRYGGIRSNPVTLNVLYG 330
           +T N +G Y C+  +   G+    VT+  + G
Sbjct: 289 ITVNNSGSYMCQAHNSATGLNRTTVTMITVSG 320


>gi|21314600 carcinoembryonic antigen-related cell adhesion molecule
           8 [Homo sapiens]
          Length = 349

 Score =  283 bits (724), Expect = 2e-76
 Identities = 157/311 (50%), Positives = 199/311 (63%), Gaps = 14/311 (4%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MGP+SAP C   I W+GLLLTASL  FWN PTTAQ+ IEA P   +EGK+VLLLVHNLPQ
Sbjct: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQ-IIYGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
           +  GY WYKG+  D    I  YV+  Q I  GPAYS RET+Y NASLL++NVT+ D GSY
Sbjct: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120

Query: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
           TL +IK    +  VTG F+V  + ETPKPSISS+N NP E  +AV   C+PET + +YLW
Sbjct: 121 TLQVIKLNLMSEEVTGQFSV--HPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLW 178

Query: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP 239
            +NGQ+LP++ RLQLS  NRTL L  VT+   GPYECEI+NP SA+ SDPVTLN+L    
Sbjct: 179 WVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPD 238

Query: 240 MPYITINNLNPREKKDVLAFTCEPKSRNYT-YIWWLNGQSLPVSPRVKRPIENRILILPS 298
            P I+ ++       + L  +C   S   + Y W +NG     + +         L +P+
Sbjct: 239 APTISPSDTYYHAGVN-LNLSCHAASNPPSQYSWSVNGTFQQYTQK---------LFIPN 288

Query: 299 VTRNETGPYQC 309
           +T   +G Y C
Sbjct: 289 ITTKNSGSYAC 299


>gi|68161541 carcinoembryonic antigen-related cell adhesion molecule
           1 isoform 2 precursor [Homo sapiens]
          Length = 464

 Score =  282 bits (722), Expect = 4e-76
 Identities = 185/443 (41%), Positives = 242/443 (54%), Gaps = 34/443 (7%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MG LSAP     + W+GLLLTASLL FWN PTTAQ+  E+ P  V+EGK+VLLLVHNLPQ
Sbjct: 1   MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQ-IIYGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
            L GY WYKG+  D    I  Y +  Q    GPA SGRET+Y NASLLIQNVTQ D G Y
Sbjct: 61  QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120

Query: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
           TL +IK        TG F V  Y E PKPSISS+N NP E  +AV   C+PET D +YLW
Sbjct: 121 TLQVIKSDLVNEEATGQFHV--YPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLW 178

Query: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP 239
            +N Q+LP++ RLQLS  NRTL L  VT+   GPYECEI+NPVSA+RSDPVTLN+     
Sbjct: 179 WINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPD 238

Query: 240 MPYITINNLNPREKKDVLAFTCEPKSR-NYTYIWWLNGQSLPVSPRVKRPIENRILILPS 298
            P I+ ++   R   + L+ +C   S     Y W +NG               + L +P+
Sbjct: 239 TPTISPSDTYYRPGAN-LSLSCYAASNPPAQYSWLINGTFQQ---------STQELFIPN 288

Query: 299 VTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDL------PRIYPSFTYYRSG-ENLDL 351
           +T N +G Y C   +   G   N  T+  +   +L      P+I  S T      ++++L
Sbjct: 289 ITVNNSGSYTCHANNSVTG--CNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNL 346

Query: 352 SCFADSNPPAEYSWTINGKFQLSGQKLFIPQITTNHS---------GLYACSVRNSATGK 402
           +C + ++      W    +   S +++ + Q  T  S         G Y C V N  + K
Sbjct: 347 TC-STNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPIS-K 404

Query: 403 EISKSMIVKVSETASPQVTYAGP 425
             S  +++ V+  A PQ     P
Sbjct: 405 NQSDPIMLNVNYNALPQENGLSP 427


>gi|19923195 carcinoembryonic antigen-related cell adhesion molecule
           1 isoform 1 precursor [Homo sapiens]
          Length = 526

 Score =  282 bits (722), Expect = 4e-76
 Identities = 185/443 (41%), Positives = 242/443 (54%), Gaps = 34/443 (7%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MG LSAP     + W+GLLLTASLL FWN PTTAQ+  E+ P  V+EGK+VLLLVHNLPQ
Sbjct: 1   MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQ-IIYGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
            L GY WYKG+  D    I  Y +  Q    GPA SGRET+Y NASLLIQNVTQ D G Y
Sbjct: 61  QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120

Query: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
           TL +IK        TG F V  Y E PKPSISS+N NP E  +AV   C+PET D +YLW
Sbjct: 121 TLQVIKSDLVNEEATGQFHV--YPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLW 178

Query: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP 239
            +N Q+LP++ RLQLS  NRTL L  VT+   GPYECEI+NPVSA+RSDPVTLN+     
Sbjct: 179 WINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPD 238

Query: 240 MPYITINNLNPREKKDVLAFTCEPKSR-NYTYIWWLNGQSLPVSPRVKRPIENRILILPS 298
            P I+ ++   R   + L+ +C   S     Y W +NG               + L +P+
Sbjct: 239 TPTISPSDTYYRPGAN-LSLSCYAASNPPAQYSWLINGTFQQ---------STQELFIPN 288

Query: 299 VTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDL------PRIYPSFTYYRSG-ENLDL 351
           +T N +G Y C   +   G   N  T+  +   +L      P+I  S T      ++++L
Sbjct: 289 ITVNNSGSYTCHANNSVTG--CNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNL 346

Query: 352 SCFADSNPPAEYSWTINGKFQLSGQKLFIPQITTNHS---------GLYACSVRNSATGK 402
           +C + ++      W    +   S +++ + Q  T  S         G Y C V N  + K
Sbjct: 347 TC-STNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPIS-K 404

Query: 403 EISKSMIVKVSETASPQVTYAGP 425
             S  +++ V+  A PQ     P
Sbjct: 405 NQSDPIMLNVNYNALPQENGLSP 427


>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
           5 preproprotein [Homo sapiens]
          Length = 702

 Score =  282 bits (722), Expect = 4e-76
 Identities = 186/441 (42%), Positives = 240/441 (54%), Gaps = 36/441 (8%)

Query: 5   SAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQNLTG 64
           SAPP    I W+ LLLTASLL FWN PTTA++ IE+ P  V+EGK+VLLLVHNLPQ+L G
Sbjct: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64

Query: 65  YIWYKGQMTDLYHYITSYVVHGQ-IIYGPAYSGRETVYSNASLLIQNVTQEDAGSYTLHI 123
           Y WYKG+  D    I  YV+  Q    GPAYSGRE +Y NASLLIQN+ Q D G YTLH+
Sbjct: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124

Query: 124 IKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWLLNG 183
           IK        TG F V  Y E PKPSISS+N  P E  +AV   C+PET DA+YLW +N 
Sbjct: 125 IKSDLVNEEATGQFRV--YPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNN 182

Query: 184 QNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPMPYI 243
           Q+LP++ RLQLS  NRTL LF VT+     Y+CE +NPVSA RSD V LN+L     P I
Sbjct: 183 QSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTI 242

Query: 244 TINNLNPREKKDVLAFTCEPKSR-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRN 302
           +  N + R  ++ L  +C   S     Y W++NG               + L +P++T N
Sbjct: 243 SPLNTSYRSGEN-LNLSCHAASNPPAQYSWFVNGTFQQ---------STQELFIPNITVN 292

Query: 303 ETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPP-- 360
            +G Y C+  +   G+    VT   +Y  + P+  P  T   S    D    A +  P  
Sbjct: 293 NSGSYTCQAHNSDTGLNRTTVTTITVYA-EPPK--PFITSNNSNPVEDEDAVALTCEPEI 349

Query: 361 --AEYSWTING-------KFQLS--GQKLFIPQITTNHSGLYACSVRNSATGKEISKSMI 409
               Y W +N        + QLS   + L +  +T N  G Y C ++N  +  + S  +I
Sbjct: 350 QNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLS-VDHSDPVI 408

Query: 410 VKV-----SETASPQVTYAGP 425
           + V       T SP  TY  P
Sbjct: 409 LNVLYGPDDPTISPSYTYYRP 429



 Score =  228 bits (581), Expect = 8e-60
 Identities = 132/322 (40%), Positives = 180/322 (55%), Gaps = 15/322 (4%)

Query: 103 NASLLIQNVTQEDAGSYTLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVME 162
           N +L + NVT+ D  SY              +    V LY     P+IS  N + R   E
Sbjct: 197 NRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNV-LYGPDA-PTISPLNTSYRSG-E 253

Query: 163 AVRLICDPET-PDASYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNP 221
            + L C   + P A Y W +NG            ++ + L++  +T   +G Y C+  N 
Sbjct: 254 NLNLSCHAASNPPAQYSWFVNGT---------FQQSTQELFIPNITVNNSGSYTCQAHNS 304

Query: 222 -VSASRSDPVTLNLLPKLPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLP 280
               +R+   T+ +  + P P+IT NN NP E +D +A TCEP+ +N TY+WW+N QSLP
Sbjct: 305 DTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLP 364

Query: 281 VSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSF 340
           VSPR++   +NR L L SVTRN+ GPY+C I+++     S+PV LNVLYGPD P I PS+
Sbjct: 365 VSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSY 424

Query: 341 TYYRSGENLDLSCFADSNPPAEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSAT 400
           TYYR G NL LSC A SNPPA+YSW I+G  Q   Q+LFI  IT  +SGLY C   NSA+
Sbjct: 425 TYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQANNSAS 484

Query: 401 GKEISKSMIVKVS-ETASPQVT 421
           G   +    + VS E   P ++
Sbjct: 485 GHSRTTVKTITVSAELPKPSIS 506



 Score =  212 bits (540), Expect = 5e-55
 Identities = 143/401 (35%), Positives = 202/401 (50%), Gaps = 42/401 (10%)

Query: 29  NLPTTAQVIIEAKPPKVS---------EGKDVLLLVHNLPQNLTGYIWYKGQMTDLYHYI 79
           N  T   + + A+PPK           E +D + L        T Y+W+           
Sbjct: 309 NRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWW----------- 357

Query: 80  TSYVVHGQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSYTLHIIKRGDGTGGVTGYFTV 139
               V+ Q +  P     +    N +L + +VT+ D G Y   I  +            V
Sbjct: 358 ----VNNQSL--PVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNV 411

Query: 140 TLYSETPKPSISSSNLNPREVMEAVRLICDPET-PDASYLWLLNGQNLPMTHRLQLSKTN 198
               + P  S S +   P   +    L C   + P A Y WL++G          + +  
Sbjct: 412 LYGPDDPTISPSYTYYRPGVNLS---LSCHAASNPPAQYSWLIDGN---------IQQHT 459

Query: 199 RTLYLFGVTKYIAGPYECEIRNPVSA-SRSDPVTLNLLPKLPMPYITINNLNPREKKDVL 257
           + L++  +T+  +G Y C+  N  S  SR+   T+ +  +LP P I+ NN  P E KD +
Sbjct: 460 QELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAV 519

Query: 258 AFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGG 317
           AFTCEP+++N TY+WW+NGQSLPVSPR++    NR L L +VTRN+   Y C I++    
Sbjct: 520 AFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSA 579

Query: 318 IRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPPAEYSWTINGKFQLSGQK 377
            RS+PVTL+VLYGPD P I P  + Y SG NL+LSC + SNP  +YSW ING  Q   Q 
Sbjct: 580 NRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQV 639

Query: 378 LFIPQITTNHSGLYACSVRNSATGK--EISKSMIVKVSETA 416
           LFI +IT N++G YAC V N ATG+   I KS+ V  S T+
Sbjct: 640 LFIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSASGTS 680


>gi|5901930 carcinoembryonic antigen-related cell adhesion molecule
           7 [Homo sapiens]
          Length = 265

 Score =  241 bits (615), Expect = 9e-64
 Identities = 131/236 (55%), Positives = 158/236 (66%), Gaps = 4/236 (1%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MG  SA P    I W+GLLLTASLL FWNLP +AQ  I+  P  V+EGK+VLL+VHN  Q
Sbjct: 1   MGSPSACPYRVCIPWQGLLLTASLLTFWNLPNSAQTNIDVVPFNVAEGKEVLLVVHNESQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYV--VHGQIIYGPAYSGRETVYSNASLLIQNVTQEDAGS 118
           NL GY WYKG+     + I  YV  +  +   GPA++GRET+Y N +LLIQNVT  DAG 
Sbjct: 61  NLYGYNWYKGERVHANYRIIGYVKNISQENAPGPAHNGRETIYPNGTLLIQNVTHNDAGF 120

Query: 119 YTLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYL 178
           YTLH+IK       VT  F V  +SE PKPSI+S+N NP E  + V L C PET + +YL
Sbjct: 121 YTLHVIKENLVNEEVTRQFYV--FSEPPKPSITSNNFNPVENKDIVVLTCQPETQNTTYL 178

Query: 179 WLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNL 234
           W +N Q+L ++ RL LS  NRTL L   TK   GPYECEI+NPV ASRSDPVTLN+
Sbjct: 179 WWVNNQSLLVSPRLLLSTDNRTLVLLSATKNDIGPYECEIQNPVGASRSDPVTLNV 234



 Score =  117 bits (292), Expect = 3e-26
 Identities = 58/132 (43%), Positives = 80/132 (60%)

Query: 198 NRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPMPYITINNLNPREKKDVL 257
           N TL +  VT   AG Y   +      +        +  + P P IT NN NP E KD++
Sbjct: 105 NGTLLIQNVTHNDAGFYTLHVIKENLVNEEVTRQFYVFSEPPKPSITSNNFNPVENKDIV 164

Query: 258 AFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGG 317
             TC+P+++N TY+WW+N QSL VSPR+    +NR L+L S T+N+ GPY+CEI++  G 
Sbjct: 165 VLTCQPETQNTTYLWWVNNQSLLVSPRLLLSTDNRTLVLLSATKNDIGPYECEIQNPVGA 224

Query: 318 IRSNPVTLNVLY 329
            RS+PVTLNV Y
Sbjct: 225 SRSDPVTLNVRY 236


>gi|164663826 pregnancy specific beta-1-glycoprotein 11 isoform 2
           [Homo sapiens]
          Length = 213

 Score =  233 bits (593), Expect = 3e-61
 Identities = 110/181 (60%), Positives = 139/181 (76%)

Query: 232 LNLLPKLPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIEN 291
           L L  + P P I+ +NLNPRE  + +  TC P++ + +Y+WW+NGQSLP++ R++    N
Sbjct: 18  LLLTVETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETN 77

Query: 292 RILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDL 351
           R L L  VT+   GPY+CEI +     RS+PVTLN+L+GPDLPRI+PS T Y SGENLDL
Sbjct: 78  RTLFLFGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDL 137

Query: 352 SCFADSNPPAEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVK 411
           SCFA+SNPPA+YSWTINGKFQLSGQKLFIPQIT  H+GLYACS RNSATG+E S S+ ++
Sbjct: 138 SCFANSNPPAQYSWTINGKFQLSGQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIR 197

Query: 412 V 412
           V
Sbjct: 198 V 198



 Score =  182 bits (461), Expect = 7e-46
 Identities = 101/193 (52%), Positives = 123/193 (63%), Gaps = 14/193 (7%)

Query: 144 ETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYL 203
           ETPKPSISSSNLNPRE ME V L C+PETPDASYLW +NGQ+LPMTHR+QLS+TNRTL+L
Sbjct: 23  ETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFL 82

Query: 204 FGVTKYIAGPYECEIRNPVSASRSDPVTLNLL--PKLPMPYITINNLNPREKKDVLAFTC 261
           FGVTKY AGPYECEI N  SASRSDPVTLNLL  P LP  + ++ +    E  D+  F  
Sbjct: 83  FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDLSCFAN 142

Query: 262 EPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSN 321
                 Y+  W +NG         K  +  + L +P +T    G Y C  R+   G  S+
Sbjct: 143 SNPPAQYS--WTING---------KFQLSGQKLFIPQITPKHNGLYACSARNSATGEESS 191

Query: 322 -PVTLNVLYGPDL 333
             +T+ V+  P L
Sbjct: 192 TSLTIRVIAPPGL 204



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 65/251 (25%), Positives = 101/251 (40%), Gaps = 44/251 (17%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MGPLSAPPCT+HI WKGLLLT           T +  I +      E  + ++L  N   
Sbjct: 1   MGPLSAPPCTEHIKWKGLLLTVE---------TPKPSISSSNLNPREAMETVILTCNPET 51

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSYT 120
               Y+W+               ++GQ +  P     +   +N +L +  VT+  AG Y 
Sbjct: 52  PDASYLWW---------------MNGQSL--PMTHRMQLSETNRTLFLFGVTKYTAGPYE 94

Query: 121 LHIIKRGDGTGGVTGYFTVTLYSETPK--PSISSSNLNPREVMEAVRLICDPET-PDASY 177
             I   G  +        +    + P+  PS++S         E + L C   + P A Y
Sbjct: 95  CEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSG-----ENLDLSCFANSNPPAQY 149

Query: 178 LWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSD-PVTLNLLP 236
            W +NG       + QLS   + L++  +T    G Y C  RN  +   S   +T+ ++ 
Sbjct: 150 SWTING-------KFQLS--GQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRVIA 200

Query: 237 KLPMPYITINN 247
              +     NN
Sbjct: 201 PPGLGTFAFNN 211


>gi|164663824 pregnancy specific beta-1-glycoprotein 11 isoform 2
           [Homo sapiens]
          Length = 213

 Score =  233 bits (593), Expect = 3e-61
 Identities = 110/181 (60%), Positives = 139/181 (76%)

Query: 232 LNLLPKLPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIEN 291
           L L  + P P I+ +NLNPRE  + +  TC P++ + +Y+WW+NGQSLP++ R++    N
Sbjct: 18  LLLTVETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETN 77

Query: 292 RILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDL 351
           R L L  VT+   GPY+CEI +     RS+PVTLN+L+GPDLPRI+PS T Y SGENLDL
Sbjct: 78  RTLFLFGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDL 137

Query: 352 SCFADSNPPAEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVK 411
           SCFA+SNPPA+YSWTINGKFQLSGQKLFIPQIT  H+GLYACS RNSATG+E S S+ ++
Sbjct: 138 SCFANSNPPAQYSWTINGKFQLSGQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIR 197

Query: 412 V 412
           V
Sbjct: 198 V 198



 Score =  182 bits (461), Expect = 7e-46
 Identities = 101/193 (52%), Positives = 123/193 (63%), Gaps = 14/193 (7%)

Query: 144 ETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYL 203
           ETPKPSISSSNLNPRE ME V L C+PETPDASYLW +NGQ+LPMTHR+QLS+TNRTL+L
Sbjct: 23  ETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFL 82

Query: 204 FGVTKYIAGPYECEIRNPVSASRSDPVTLNLL--PKLPMPYITINNLNPREKKDVLAFTC 261
           FGVTKY AGPYECEI N  SASRSDPVTLNLL  P LP  + ++ +    E  D+  F  
Sbjct: 83  FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDLSCFAN 142

Query: 262 EPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSN 321
                 Y+  W +NG         K  +  + L +P +T    G Y C  R+   G  S+
Sbjct: 143 SNPPAQYS--WTING---------KFQLSGQKLFIPQITPKHNGLYACSARNSATGEESS 191

Query: 322 -PVTLNVLYGPDL 333
             +T+ V+  P L
Sbjct: 192 TSLTIRVIAPPGL 204



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 65/251 (25%), Positives = 101/251 (40%), Gaps = 44/251 (17%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MGPLSAPPCT+HI WKGLLLT           T +  I +      E  + ++L  N   
Sbjct: 1   MGPLSAPPCTEHIKWKGLLLTVE---------TPKPSISSSNLNPREAMETVILTCNPET 51

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSYT 120
               Y+W+               ++GQ +  P     +   +N +L +  VT+  AG Y 
Sbjct: 52  PDASYLWW---------------MNGQSL--PMTHRMQLSETNRTLFLFGVTKYTAGPYE 94

Query: 121 LHIIKRGDGTGGVTGYFTVTLYSETPK--PSISSSNLNPREVMEAVRLICDPET-PDASY 177
             I   G  +        +    + P+  PS++S         E + L C   + P A Y
Sbjct: 95  CEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSG-----ENLDLSCFANSNPPAQY 149

Query: 178 LWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSD-PVTLNLLP 236
            W +NG       + QLS   + L++  +T    G Y C  RN  +   S   +T+ ++ 
Sbjct: 150 SWTING-------KFQLS--GQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRVIA 200

Query: 237 KLPMPYITINN 247
              +     NN
Sbjct: 201 PPGLGTFAFNN 211


>gi|52317156 carcinoembryonic antigen-related cell adhesion molecule
           isoform 2 [Homo sapiens]
          Length = 292

 Score =  174 bits (440), Expect = 2e-43
 Identities = 99/235 (42%), Positives = 136/235 (57%), Gaps = 4/235 (1%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MGP SA P  + I W+GLLLTASLL FWN PTTA + I + P +V+EG++V L V  LP+
Sbjct: 1   MGPPSACPHRECIPWQGLLLTASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPE 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQI-IYGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
           NL  Y WYKG+  +    I +YV+   +   GPAYSGRET+  +  L  QNVT ED G Y
Sbjct: 61  NLYSYGWYKGKTVEPNQLIAAYVIDTHVRTPGPAYSGRETISPSGDLHFQNVTLEDTGYY 120

Query: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
            L +  R       + +  V  Y    +PSI +S+    E   +V L C       S+ W
Sbjct: 121 NLQVTYRNSQIEQASHHLRV--YESVAQPSIQASSTTVTE-KGSVVLTCHTNNTGTSFQW 177

Query: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNL 234
           + N Q L +T R++LS  N  L +  + +  AG Y+CE+ NPVS++RSDP+ L +
Sbjct: 178 IFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLKLTV 232



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 45/174 (25%), Positives = 69/174 (39%), Gaps = 14/174 (8%)

Query: 201 LYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPMPYITINNLNPREKKDVLAFT 260
           L+   VT    G Y  ++    S        L +   +  P I  ++    EK  V+  T
Sbjct: 107 LHFQNVTLEDTGYYNLQVTYRNSQIEQASHHLRVYESVAQPSIQASSTTVTEKGSVV-LT 165

Query: 261 CEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRS 320
           C   +   ++ W  N Q L V+ R+K    N +L +  + + + G YQCE+ +     RS
Sbjct: 166 CHTNNTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRS 225

Query: 321 NPVTLNVLY------------GPDLPRIYPSFTYYR-SGENLDLSCFADSNPPA 361
           +P+ L V Y            G  L      F   R +G   D S F +  PPA
Sbjct: 226 DPLKLTVKYDNTLGILIGVLVGSLLVAALVCFLLLRKTGRASDQSDFREQQPPA 279


>gi|148612793 carcinoembryonic antigen-related cell adhesion
           molecule isoform 1 [Homo sapiens]
          Length = 293

 Score =  174 bits (440), Expect = 2e-43
 Identities = 99/235 (42%), Positives = 136/235 (57%), Gaps = 4/235 (1%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MGP SA P  + I W+GLLLTASLL FWN PTTA + I + P +V+EG++V L V  LP+
Sbjct: 1   MGPPSACPHRECIPWQGLLLTASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPE 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQI-IYGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
           NL  Y WYKG+  +    I +YV+   +   GPAYSGRET+  +  L  QNVT ED G Y
Sbjct: 61  NLYSYGWYKGKTVEPNQLIAAYVIDTHVRTPGPAYSGRETISPSGDLHFQNVTLEDTGYY 120

Query: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179
            L +  R       + +  V  Y    +PSI +S+    E   +V L C       S+ W
Sbjct: 121 NLQVTYRNSQIEQASHHLRV--YESVAQPSIQASSTTVTE-KGSVVLTCHTNNTGTSFQW 177

Query: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNL 234
           + N Q L +T R++LS  N  L +  + +  AG Y+CE+ NPVS++RSDP+ L +
Sbjct: 178 IFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLKLTV 232



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 44/175 (25%), Positives = 69/175 (39%), Gaps = 15/175 (8%)

Query: 201 LYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPMPYITINNLNPREKKDVLAFT 260
           L+   VT    G Y  ++    S        L +   +  P I  ++    EK  V+  T
Sbjct: 107 LHFQNVTLEDTGYYNLQVTYRNSQIEQASHHLRVYESVAQPSIQASSTTVTEKGSVV-LT 165

Query: 261 CEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRS 320
           C   +   ++ W  N Q L V+ R+K    N +L +  + + + G YQCE+ +     RS
Sbjct: 166 CHTNNTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRS 225

Query: 321 NP-------------VTLNVLYGPDLPRIYPSFTYYR-SGENLDLSCFADSNPPA 361
           +P             + + VL G  L      F   R +G   D S F +  PPA
Sbjct: 226 DPLKLTVKSDDNTLGILIGVLVGSLLVAALVCFLLLRKTGRASDQSDFREQQPPA 280


>gi|121114300 carcinoembryonic antigen-related cell adhesion
           molecule 3 precursor [Homo sapiens]
          Length = 252

 Score =  159 bits (401), Expect = 6e-39
 Identities = 85/140 (60%), Positives = 98/140 (70%), Gaps = 1/140 (0%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MGP SA P  + I W+GLLLTASLLNFWN PTTA++ IE+ P  V+EGK+VLLLVHNLPQ
Sbjct: 1   MGPPSASPHRECIPWQGLLLTASLLNFWNPPTTAKLTIESMPLSVAEGKEVLLLVHNLPQ 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVV-HGQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
           +L GY WYKG+  D    I  YV+   Q   G AYSGRET+Y+NASLLIQNVTQ D G Y
Sbjct: 61  HLFGYSWYKGERVDGNSLIVGYVIGTQQATPGAAYSGRETIYTNASLLIQNVTQNDIGFY 120

Query: 120 TLHIIKRGDGTGGVTGYFTV 139
           TL +IK        TG F V
Sbjct: 121 TLQVIKSDLVNEEATGQFHV 140


>gi|156564378 carcinoembryonic antigen-related cell adhesion
           molecule 20 5L [Homo sapiens]
          Length = 596

 Score =  141 bits (355), Expect = 1e-33
 Identities = 123/442 (27%), Positives = 192/442 (43%), Gaps = 61/442 (13%)

Query: 15  WKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQNLTGY--------- 65
           W G+LL+ASL   W+ P  AQ+ + A P   ++ +DV+L V   P+    +         
Sbjct: 11  WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70

Query: 66  ---------IWYKGQMTDLYHYITSYVVHGQIIY-----GPAYSGRETVYSNASLL-IQN 110
                    I  K  +T    Y T+  V+  I +        +  R  +  +  +L I  
Sbjct: 71  SIAVSPGTAIEQKDMVT---FYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILI 127

Query: 111 VTQEDAGSYTLH-----IIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVR 165
           V +ED+G+Y        + +R D        F    Y   P      S +   EV+E + 
Sbjct: 128 VQREDSGTYQCEARDALLSQRSDPI------FLDVKYGPDPVEIKLESGVASGEVVEVME 181

Query: 166 ------LICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIR 219
                 L      P  +Y W L    L        S T RT  +  V++   G Y C + 
Sbjct: 182 GSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVS 233

Query: 220 NPVS-ASRSDPVTLNLLPKLPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQS 278
           N  +  S    + + +L  L MP +  ++LN  E    +  TC+  +++    W+L+GQ 
Sbjct: 234 NSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQP 293

Query: 279 LPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRI-- 336
           L  S  ++   +NR LI+  + RN+TGPY CE+ +     RS P+ L + YGPD   I  
Sbjct: 294 LLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITR 353

Query: 337 -----YPSFTYYRSGENLDLSCFADSNPPAEYSWTI-NGKFQLSGQKLFIPQITTNHSGL 390
                  S        +L L C+A+S P AEY WT+ +   +  G++L I  +T  H G+
Sbjct: 354 ESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGI 413

Query: 391 YACSVRNSATGKEISKSMIVKV 412
           Y C+  NS TG   S S++VKV
Sbjct: 414 YNCTASNSLTGLARSTSVLVKV 435



 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 69/228 (30%), Positives = 104/228 (45%), Gaps = 21/228 (9%)

Query: 220 NPVSASRSDPVTLNLL--PKLPM----------PYITINNLNPREKKDVLAFTCEPKSRN 267
           NP+ A++S+ V L +   P+ P           P I ++     E+KD++ F C  K  N
Sbjct: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96

Query: 268 YTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNV 327
            T  W  N  S+    R++   + +IL +  V R ++G YQCE RD     RS+P+ L+V
Sbjct: 97  ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156

Query: 328 LYGPDLPRI-------YPSFTYYRSGENLDLSCFADSNPPAEYSWTINGKFQLSGQKLF- 379
            YGPD   I                G ++       S+PP  Y+W +         + F 
Sbjct: 157 KYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFT 216

Query: 380 IPQITTNHSGLYACSVRNSATGKEISKSMIVKVSETAS-PQVTYAGPN 426
           I  ++  H GLY C V NSAT      ++ V+V ET + PQV  +  N
Sbjct: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLN 264



 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 61/241 (25%), Positives = 96/241 (39%), Gaps = 22/241 (9%)

Query: 101 YSNASLLIQNVTQEDAGSYTLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREV 160
           ++  +  I  V++E  G Y   +         + G   V +      P +  S+LN  E 
Sbjct: 210 HTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL-GTLKVRVLETLTMPQVVPSSLNLVEN 268

Query: 161 MEAVRLICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRN 220
             +V L C       +  W L+GQ L  +  LQLS  NRTL + G+ +   GPY CE+ N
Sbjct: 269 ARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328

Query: 221 PVSASRSDPVTLNLLPKLPMPYITINNLN------PREKKDVLAFTCEPKSR-NYTYIWW 273
             S +RS+P+ L +       +IT  + +        E    L   C  +S+    Y W 
Sbjct: 329 WGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWT 388

Query: 274 L---NGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYG 330
           L    G+ L              LI+ ++T    G Y C   +   G+  +   L  + G
Sbjct: 389 LEHSTGEHL-----------GEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVG 437

Query: 331 P 331
           P
Sbjct: 438 P 438


>gi|156564393 carcinoembryonic antigen-related cell adhesion
           molecule 20 5S [Homo sapiens]
          Length = 584

 Score =  141 bits (355), Expect = 1e-33
 Identities = 123/442 (27%), Positives = 192/442 (43%), Gaps = 61/442 (13%)

Query: 15  WKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQNLTGY--------- 65
           W G+LL+ASL   W+ P  AQ+ + A P   ++ +DV+L V   P+    +         
Sbjct: 11  WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70

Query: 66  ---------IWYKGQMTDLYHYITSYVVHGQIIY-----GPAYSGRETVYSNASLL-IQN 110
                    I  K  +T    Y T+  V+  I +        +  R  +  +  +L I  
Sbjct: 71  SIAVSPGTAIEQKDMVT---FYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILI 127

Query: 111 VTQEDAGSYTLH-----IIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVR 165
           V +ED+G+Y        + +R D        F    Y   P      S +   EV+E + 
Sbjct: 128 VQREDSGTYQCEARDALLSQRSDPI------FLDVKYGPDPVEIKLESGVASGEVVEVME 181

Query: 166 ------LICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIR 219
                 L      P  +Y W L    L        S T RT  +  V++   G Y C + 
Sbjct: 182 GSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVS 233

Query: 220 NPVS-ASRSDPVTLNLLPKLPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQS 278
           N  +  S    + + +L  L MP +  ++LN  E    +  TC+  +++    W+L+GQ 
Sbjct: 234 NSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQP 293

Query: 279 LPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRI-- 336
           L  S  ++   +NR LI+  + RN+TGPY CE+ +     RS P+ L + YGPD   I  
Sbjct: 294 LLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITR 353

Query: 337 -----YPSFTYYRSGENLDLSCFADSNPPAEYSWTI-NGKFQLSGQKLFIPQITTNHSGL 390
                  S        +L L C+A+S P AEY WT+ +   +  G++L I  +T  H G+
Sbjct: 354 ESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGI 413

Query: 391 YACSVRNSATGKEISKSMIVKV 412
           Y C+  NS TG   S S++VKV
Sbjct: 414 YNCTASNSLTGLARSTSVLVKV 435



 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 69/228 (30%), Positives = 104/228 (45%), Gaps = 21/228 (9%)

Query: 220 NPVSASRSDPVTLNLL--PKLPM----------PYITINNLNPREKKDVLAFTCEPKSRN 267
           NP+ A++S+ V L +   P+ P           P I ++     E+KD++ F C  K  N
Sbjct: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96

Query: 268 YTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNV 327
            T  W  N  S+    R++   + +IL +  V R ++G YQCE RD     RS+P+ L+V
Sbjct: 97  ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156

Query: 328 LYGPDLPRI-------YPSFTYYRSGENLDLSCFADSNPPAEYSWTINGKFQLSGQKLF- 379
            YGPD   I                G ++       S+PP  Y+W +         + F 
Sbjct: 157 KYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFT 216

Query: 380 IPQITTNHSGLYACSVRNSATGKEISKSMIVKVSETAS-PQVTYAGPN 426
           I  ++  H GLY C V NSAT      ++ V+V ET + PQV  +  N
Sbjct: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLN 264



 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 61/241 (25%), Positives = 96/241 (39%), Gaps = 22/241 (9%)

Query: 101 YSNASLLIQNVTQEDAGSYTLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREV 160
           ++  +  I  V++E  G Y   +         + G   V +      P +  S+LN  E 
Sbjct: 210 HTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL-GTLKVRVLETLTMPQVVPSSLNLVEN 268

Query: 161 MEAVRLICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRN 220
             +V L C       +  W L+GQ L  +  LQLS  NRTL + G+ +   GPY CE+ N
Sbjct: 269 ARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328

Query: 221 PVSASRSDPVTLNLLPKLPMPYITINNLN------PREKKDVLAFTCEPKSR-NYTYIWW 273
             S +RS+P+ L +       +IT  + +        E    L   C  +S+    Y W 
Sbjct: 329 WGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWT 388

Query: 274 L---NGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYG 330
           L    G+ L              LI+ ++T    G Y C   +   G+  +   L  + G
Sbjct: 389 LEHSTGEHL-----------GEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVG 437

Query: 331 P 331
           P
Sbjct: 438 P 438


>gi|71143132 carcinoembryonic antigen-related cell adhesion molecule
           4 [Homo sapiens]
          Length = 244

 Score =  132 bits (333), Expect = 5e-31
 Identities = 72/140 (51%), Positives = 85/140 (60%), Gaps = 1/140 (0%)

Query: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60
           MGP SA P   H  W+GLL+TASLL FW+ PTT Q  IEA P   +EGKDVLLL  N+ +
Sbjct: 1   MGPPSAAPRGGHRPWQGLLITASLLTFWHPPTTVQFTIEALPSSAAEGKDVLLLACNISE 60

Query: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQI-IYGPAYSGRETVYSNASLLIQNVTQEDAGSY 119
            +  Y W+KG+  +    I  Y+   Q  I G AYSGRETVY N SLL QN+T EDAGSY
Sbjct: 61  TIQAYYWHKGKTAEGSPLIAGYITDIQANIPGAAYSGRETVYPNGSLLFQNITLEDAGSY 120

Query: 120 TLHIIKRGDGTGGVTGYFTV 139
           TL  I     +   TG   V
Sbjct: 121 TLRTINASYDSDQATGQLHV 140


>gi|85861202 carcinoembryonic antigen-related cell adhesion molecule
           16 [Homo sapiens]
          Length = 484

 Score =  132 bits (332), Expect = 6e-31
 Identities = 96/300 (32%), Positives = 146/300 (48%), Gaps = 23/300 (7%)

Query: 18  LLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQMTDLYH 77
           LLL+A+ LN       A++ I  +P + SEG +V L+VH L   L  Y WY G    + +
Sbjct: 68  LLLSATFLN-----VGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122

Query: 78  YITSYVVH-GQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSYTLHIIKRGDGTGGVTGY 136
            + SY+V  G    GPA++GRE V  + SL IQ +    +G+Y L    R   T    GY
Sbjct: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTE--VGY 180

Query: 137 FTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWLLNGQNLPMTHRLQLSK 196
             V ++    +P++ +++    E  + +RL+C   +P A   W  NG  LP+  RL LS 
Sbjct: 181 GHVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSP 240

Query: 197 TNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLL---PKLPMPYITINNLNPREK 253
             R L   G+ +  AG Y+CE+ NPVS SRS+P+ L +     ++ +   +        K
Sbjct: 241 DGRVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIK 300

Query: 254 KDV---LAFTCEPKS-RNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQC 309
            D    L   C  +S     Y+W  NGQ+L      K   ++  L + S+T  + G Y C
Sbjct: 301 VDFNTSLTLWCVSRSCPEPEYVWTFNGQAL------KNGQDH--LNISSMTAAQEGTYTC 352



 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 62/188 (32%), Positives = 89/188 (47%), Gaps = 10/188 (5%)

Query: 238 LPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILP 297
           L  P +  N+    E++D L   C   S      W+ NG +LPV+ R+    + R+L   
Sbjct: 189 LAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARH 248

Query: 298 SVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSG--------ENL 349
            + R E G YQCE+ +     RS P+ L V +GP+   I    T  R+G         +L
Sbjct: 249 GIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDST-TRTGCTIKVDFNTSL 307

Query: 350 DLSCFADSNPPAEYSWTINGKFQLSGQ-KLFIPQITTNHSGLYACSVRNSATGKEISKSM 408
            L C + S P  EY WT NG+   +GQ  L I  +T    G Y C  +N+ T    S S+
Sbjct: 308 TLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASV 367

Query: 409 IVKVSETA 416
           +VK+S  A
Sbjct: 368 VVKLSAAA 375



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 33/83 (39%), Positives = 49/83 (59%), Gaps = 1/83 (1%)

Query: 42  PPKVSEGKDVLLLVHNLPQNLTGYIWYKGQMTDLYHYITSYVVHGQIIYGPAYSGRETVY 101
           P K +EG+DV L V   P++L  Y WY+G  ++  + + S +  G  I GPA++GRE  +
Sbjct: 384 PTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEP-NRLLSQLPSGTWIAGPAHTGREVGF 442

Query: 102 SNASLLIQNVTQEDAGSYTLHII 124
            N SLL+Q +   D G YTL  +
Sbjct: 443 PNCSLLVQKLNLTDTGRYTLKTV 465


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,807,993
Number of Sequences: 37866
Number of extensions: 900274
Number of successful extensions: 4023
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 117
Number of HSP's successfully gapped in prelim test: 203
Number of HSP's that attempted gapping in prelim test: 2209
Number of HSP's gapped (non-prelim): 1374
length of query: 435
length of database: 18,247,518
effective HSP length: 105
effective length of query: 330
effective length of database: 14,271,588
effective search space: 4709624040
effective search space used: 4709624040
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.