BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens] (1217 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens] 2443 0.0 gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens] 2246 0.0 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 96 3e-19 gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 93 2e-18 gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 90 1e-17 gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 86 2e-16 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 81 5e-15 gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 79 3e-14 gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 79 3e-14 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 77 8e-14 gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 77 8e-14 gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens] 77 1e-13 gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens] 77 1e-13 gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 77 1e-13 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 75 3e-13 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 75 3e-13 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 75 3e-13 gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 74 6e-13 gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens] 74 6e-13 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 74 8e-13 gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 73 2e-12 gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 72 3e-12 gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo ... 71 5e-12 gi|125988409 RED protein [Homo sapiens] 71 7e-12 gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 70 1e-11 gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 70 1e-11 gi|34878777 ring finger protein 20 [Homo sapiens] 70 1e-11 gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 70 1e-11 gi|14670268 RD RNA-binding protein [Homo sapiens] 69 3e-11 gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 68 5e-11 >gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens] Length = 1217 Score = 2443 bits (6332), Expect = 0.0 Identities = 1217/1217 (100%), Positives = 1217/1217 (100%) Query: 1 MKGMSHEPKSPSLGMLSTATRTTATVNPLTPSPLNGALVPSGSPATSSALSAQAAPSSSF 60 MKGMSHEPKSPSLGMLSTATRTTATVNPLTPSPLNGALVPSGSPATSSALSAQAAPSSSF Sbjct: 1 MKGMSHEPKSPSLGMLSTATRTTATVNPLTPSPLNGALVPSGSPATSSALSAQAAPSSSF 60 Query: 61 AAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPST 120 AAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPST Sbjct: 61 AAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPST 120 Query: 121 PPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQEKAGGPAIPSHLLSTP 180 PPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQEKAGGPAIPSHLLSTP Sbjct: 121 PPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQEKAGGPAIPSHLLSTP 180 Query: 181 YPFGLSPSSVVQDSRFPPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTTDDLRMSSLPPLG 240 YPFGLSPSSVVQDSRFPPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTTDDLRMSSLPPLG Sbjct: 181 YPFGLSPSSVVQDSRFPPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTTDDLRMSSLPPLG 240 Query: 241 LDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLH 300 LDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLH Sbjct: 241 LDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLH 300 Query: 301 LSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKE 360 LSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKE Sbjct: 301 LSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKE 360 Query: 361 REREREKEREQEKEREREKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGH 420 REREREKEREQEKEREREKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGH Sbjct: 361 REREREKEREQEKEREREKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGH 420 Query: 421 ATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSS 480 ATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSS Sbjct: 421 ATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSS 480 Query: 481 SAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEH 540 SAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEH Sbjct: 481 SAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEH 540 Query: 541 RPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQLHAAPTALWNPVSLMDNTLETRRA 600 RPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQLHAAPTALWNPVSLMDNTLETRRA Sbjct: 541 RPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQLHAAPTALWNPVSLMDNTLETRRA 600 Query: 601 ESHSLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPAPLDKYQPPPPPPREGG 660 ESHSLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPAPLDKYQPPPPPPREGG Sbjct: 601 ESHSLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPAPLDKYQPPPPPPREGG 660 Query: 661 SLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSGPLKPGSPYRPPVPRAP 720 SLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSGPLKPGSPYRPPVPRAP Sbjct: 661 SLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSGPLKPGSPYRPPVPRAP 720 Query: 721 DPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAE 780 DPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAE Sbjct: 721 DPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAE 780 Query: 781 QPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPTIQSKRQTPS 840 QPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPTIQSKRQTPS Sbjct: 781 QPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPTIQSKRQTPS 840 Query: 841 PRLALSTRYSPDEMNNSPNFEEKKKFLTIFNLTHISAEKRKDKERLVEMLRAMKQKALSA 900 PRLALSTRYSPDEMNNSPNFEEKKKFLTIFNLTHISAEKRKDKERLVEMLRAMKQKALSA Sbjct: 841 PRLALSTRYSPDEMNNSPNFEEKKKFLTIFNLTHISAEKRKDKERLVEMLRAMKQKALSA 900 Query: 901 AVADSLTNSPRDSPAVSLSEPATQQASLDVEKPVGVAASLSDIPKAAEPGKLEQVRPQEL 960 AVADSLTNSPRDSPAVSLSEPATQQASLDVEKPVGVAASLSDIPKAAEPGKLEQVRPQEL Sbjct: 901 AVADSLTNSPRDSPAVSLSEPATQQASLDVEKPVGVAASLSDIPKAAEPGKLEQVRPQEL 960 Query: 961 SRVQELAPASGEKARLSEAPGGKKSLSMLHYIRGAAPKDIPVPLSHSTNGKSKPWEPFVA 1020 SRVQELAPASGEKARLSEAPGGKKSLSMLHYIRGAAPKDIPVPLSHSTNGKSKPWEPFVA Sbjct: 961 SRVQELAPASGEKARLSEAPGGKKSLSMLHYIRGAAPKDIPVPLSHSTNGKSKPWEPFVA 1020 Query: 1021 EEFAHQFHESVLQSTQKALQKHKGSVAVLSAEQNHKVDTSVHYNIPELQSSSRAPPPQHN 1080 EEFAHQFHESVLQSTQKALQKHKGSVAVLSAEQNHKVDTSVHYNIPELQSSSRAPPPQHN Sbjct: 1021 EEFAHQFHESVLQSTQKALQKHKGSVAVLSAEQNHKVDTSVHYNIPELQSSSRAPPPQHN 1080 Query: 1081 GQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQ 1140 GQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQ Sbjct: 1081 GQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQ 1140 Query: 1141 NLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERERLQAELDHLRKCL 1200 NLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERERLQAELDHLRKCL Sbjct: 1141 NLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERERLQAELDHLRKCL 1200 Query: 1201 ALPAMHWPRGYLKGYPR 1217 ALPAMHWPRGYLKGYPR Sbjct: 1201 ALPAMHWPRGYLKGYPR 1217 >gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens] Length = 1113 Score = 2246 bits (5821), Expect = 0.0 Identities = 1113/1113 (100%), Positives = 1113/1113 (100%) Query: 105 MGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQ 164 MGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQ Sbjct: 1 MGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQ 60 Query: 165 EKAGGPAIPSHLLSTPYPFGLSPSSVVQDSRFPPLNLQRPVHHVVPPSTVTEDYLRSFRP 224 EKAGGPAIPSHLLSTPYPFGLSPSSVVQDSRFPPLNLQRPVHHVVPPSTVTEDYLRSFRP Sbjct: 61 EKAGGPAIPSHLLSTPYPFGLSPSSVVQDSRFPPLNLQRPVHHVVPPSTVTEDYLRSFRP 120 Query: 225 YHTTDDLRMSSLPPLGLDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIP 284 YHTTDDLRMSSLPPLGLDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIP Sbjct: 121 YHTTDDLRMSSLPPLGLDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIP 180 Query: 285 TPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRRERERE 344 TPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRRERERE Sbjct: 181 TPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRRERERE 240 Query: 345 REREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKELLAAKAL 404 REREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKELLAAKAL Sbjct: 241 REREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKELLAAKAL 300 Query: 405 EPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVPTPHHT 464 EPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVPTPHHT Sbjct: 301 EPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVPTPHHT 360 Query: 465 VPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLE 524 VPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLE Sbjct: 361 VPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLE 420 Query: 525 QHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQLHAAPTAL 584 QHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQLHAAPTAL Sbjct: 421 QHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQLHAAPTAL 480 Query: 585 WNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPA 644 WNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPA Sbjct: 481 WNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPA 540 Query: 645 PLDKYQPPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSG 704 PLDKYQPPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSG Sbjct: 541 PLDKYQPPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSG 600 Query: 705 PLKPGSPYRPPVPRAPDPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYD 764 PLKPGSPYRPPVPRAPDPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYD Sbjct: 601 PLKPGSPYRPPVPRAPDPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYD 660 Query: 765 ESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRE 824 ESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRE Sbjct: 661 ESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRE 720 Query: 825 RSPSPPTIQSKRQTPSPRLALSTRYSPDEMNNSPNFEEKKKFLTIFNLTHISAEKRKDKE 884 RSPSPPTIQSKRQTPSPRLALSTRYSPDEMNNSPNFEEKKKFLTIFNLTHISAEKRKDKE Sbjct: 721 RSPSPPTIQSKRQTPSPRLALSTRYSPDEMNNSPNFEEKKKFLTIFNLTHISAEKRKDKE 780 Query: 885 RLVEMLRAMKQKALSAAVADSLTNSPRDSPAVSLSEPATQQASLDVEKPVGVAASLSDIP 944 RLVEMLRAMKQKALSAAVADSLTNSPRDSPAVSLSEPATQQASLDVEKPVGVAASLSDIP Sbjct: 781 RLVEMLRAMKQKALSAAVADSLTNSPRDSPAVSLSEPATQQASLDVEKPVGVAASLSDIP 840 Query: 945 KAAEPGKLEQVRPQELSRVQELAPASGEKARLSEAPGGKKSLSMLHYIRGAAPKDIPVPL 1004 KAAEPGKLEQVRPQELSRVQELAPASGEKARLSEAPGGKKSLSMLHYIRGAAPKDIPVPL Sbjct: 841 KAAEPGKLEQVRPQELSRVQELAPASGEKARLSEAPGGKKSLSMLHYIRGAAPKDIPVPL 900 Query: 1005 SHSTNGKSKPWEPFVAEEFAHQFHESVLQSTQKALQKHKGSVAVLSAEQNHKVDTSVHYN 1064 SHSTNGKSKPWEPFVAEEFAHQFHESVLQSTQKALQKHKGSVAVLSAEQNHKVDTSVHYN Sbjct: 901 SHSTNGKSKPWEPFVAEEFAHQFHESVLQSTQKALQKHKGSVAVLSAEQNHKVDTSVHYN 960 Query: 1065 IPELQSSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQ 1124 IPELQSSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQ Sbjct: 961 IPELQSSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQ 1020 Query: 1125 GIEAVFEAYQEHIEEQNLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVS 1184 GIEAVFEAYQEHIEEQNLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVS Sbjct: 1021 GIEAVFEAYQEHIEEQNLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVS 1080 Query: 1185 ERERLQAELDHLRKCLALPAMHWPRGYLKGYPR 1217 ERERLQAELDHLRKCLALPAMHWPRGYLKGYPR Sbjct: 1081 ERERLQAELDHLRKCLALPAMHWPRGYLKGYPR 1113 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 95.5 bits (236), Expect = 3e-19 Identities = 100/365 (27%), Positives = 162/365 (44%), Gaps = 58/365 (15%) Query: 321 ERMSGLSAERLQMDEELR-REREREREREREREADREREKEREREREKEREQEKEREREK 379 ER S + +R + E+ R RERERERERERERE +RERE+ERERERE+ERE+E+E+++++ Sbjct: 372 ERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKR 431 Query: 380 ERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEK 439 +RE + E E+R E++L +A L E+ + T E K +E+ R E Sbjct: 432 DREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERK--KTREYEKEAEREEERRREM 489 Query: 440 LKDAGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLA 499 K+A K ++ L P +AL + + E++ A Sbjct: 490 AKEA-----KRLKEFLEDYDDDRDD-------------PKYYRGSALQKRLRDREKEMEA 531 Query: 500 RQRRLRQEKED----RQSQVSE------FRQQVLEQHLDMGRPP---VPAEAEHRPESTT 546 +R ++EKE+ RQ ++E Q +EQ + R P E+E E Sbjct: 532 DERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQ 591 Query: 547 RPGPNRHEP-GGRDPPQHFGGPPPLISPKPQLHAAPTALWN----------PVSLM---D 592 R EP + P+ P + P + +A N P ++ + Sbjct: 592 EKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDESPCGIIIPHE 651 Query: 593 NTLETRRAESH----------SLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKRE 642 N+ + ++ E H + P ++ +P+ V F E +++ PRKR+ Sbjct: 652 NSPDQQQPEEHRPKIGLSLKLGASNSPGQPNSVKRKKLPVDSVFNKFEDEDSDDVPRKRK 711 Query: 643 PAPLD 647 PLD Sbjct: 712 LVPLD 716 Score = 84.3 bits (207), Expect = 6e-16 Identities = 45/77 (58%), Positives = 59/77 (76%), Gaps = 2/77 (2%) Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380 E G + Q E+ RRERERERERERER +RERE+EREREREKE+E+E+ERER+++ Sbjct: 292 EEEKGKKEKERQEIEKERRERERERERERERR-EREREREREREREKEKERERERERDRD 350 Query: 381 RERELERQREQRAREKE 397 R+R ER R+ R RE++ Sbjct: 351 RDRTKERDRD-RDRERD 366 Score = 80.5 bits (197), Expect = 9e-15 Identities = 41/72 (56%), Positives = 62/72 (86%), Gaps = 3/72 (4%) Query: 329 ERLQMDEELR-RERERERERE-REREADREREKEREREREKEREQEKEREREKERERELE 386 ER ++++E R RERERERERE RERE +RERE+ERE+E+E+ERE+E++R+R++ +ER+ + Sbjct: 301 ERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRD 360 Query: 387 RQREQ-RAREKE 397 R RE+ R R++E Sbjct: 361 RDRERDRDRDRE 372 Score = 63.2 bits (152), Expect = 1e-09 Identities = 33/81 (40%), Positives = 56/81 (69%), Gaps = 2/81 (2%) Query: 318 LHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQ-EKERE 376 + ++ +S E + + ++ E + ++E+ER+ + +ERERERE+ERE+ E+ERE Sbjct: 269 MEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERE 328 Query: 377 REKERERELERQREQRAREKE 397 RE+ERERE E++RE R RE++ Sbjct: 329 REREREREKEKERE-RERERD 348 Score = 55.1 bits (131), Expect = 4e-07 Identities = 52/211 (24%), Positives = 87/211 (41%), Gaps = 26/211 (12%) Query: 317 ALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKE-- 374 A + ER+ + E +E ERE ER RE + +R KE + + +R+ K Sbjct: 455 AAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYR 514 Query: 375 ----REREKERERELERQREQRAREKELLAAKALEPSFL------PVAELHGLRGHATEE 424 ++R ++RE+E+E R REKE L + + L P AEL + A Sbjct: 515 GSALQKRLRDREKEMEADERDRKREKEEL--EEIRQRLLAEGHPDPDAELQRMEQEAERR 572 Query: 425 R---------GKPSEQLTPTRAEKLKDAGLQAPKPVQHP-LHPVPTPHHTVPSLISNHG- 473 R + E+ + EK ++ + +P Q P L P P + PS+ S G Sbjct: 573 RQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGN 632 Query: 474 -IFSLPSSSAATALLIQRTNEEEKWLARQRR 503 + P + ++I N ++ + R Sbjct: 633 ATPNTPGDESPCGIIIPHENSPDQQQPEEHR 663 Score = 54.3 bits (129), Expect = 7e-07 Identities = 33/73 (45%), Positives = 52/73 (71%), Gaps = 7/73 (9%) Query: 331 LQMDEELR----REREREREREREREADR-EREKEREREREKEREQEKEREREKE-RERE 384 ++M+E+ R RE + R+ ++ E ++ ++EKER+ ++ RE+E+ERERE+E RERE Sbjct: 267 IEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERE 326 Query: 385 LERQREQRAREKE 397 ER+RE R REKE Sbjct: 327 RERERE-REREKE 338 Score = 33.5 bits (75), Expect = 1.3 Identities = 51/217 (23%), Positives = 87/217 (40%), Gaps = 35/217 (16%) Query: 743 EERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLT 802 EERRR A+E + + YD D+ + + R A Q L+ ++ + ++ Sbjct: 483 EERRREMAKEAKRLKEFLEDYD--DDRDDPKYYRGSALQKRLR-----DREKEMEADERD 535 Query: 803 TQQQKEELVAQKRRKRRRMLRERSPSPPT-IQSKRQTPSPRLALSTRYSPDEMNNSPNFE 861 +++KEEL R+R+L E P P +Q Q R + P+ S E Sbjct: 536 RKREKEEL----EEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPE----SEEEE 587 Query: 862 EKKKFLTIFNLTHISAEKRKDKERLVEMLRAMKQKALSAAVADSLTNSPRDSPAVSLSEP 921 E+K+ EK + +E +E +QK ++++P S A + P Sbjct: 588 EEKQ------------EKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATP 635 Query: 922 ATQQASLDVEKPVGVAASLSDIPKAAEPGKLEQVRPQ 958 T E P G+ + P +P E+ RP+ Sbjct: 636 NTP----GDESPCGIIIPHENSPDQQQP---EEHRPK 665 Score = 32.0 bits (71), Expect = 3.7 Identities = 28/146 (19%), Positives = 66/146 (45%), Gaps = 32/146 (21%) Query: 1082 QQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFE---------- 1131 ++E R+ +E ++D + + EED+ED + ++ +RK + EA ++ Sbjct: 410 EREREREREREREREREKDKKRDREEDEEDAYERRKL-ERKLREKEAAYQERLKNWEIRE 468 Query: 1132 -----AYQEHIEEQNLERQVLQTQCRRL------------EARHYSLSLTAEQLSHSVAE 1174 Y++ E + R+ + + +RL + ++Y S ++L E Sbjct: 469 RKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKE 528 Query: 1175 LRSQKQKMVSERERLQAELDHLRKCL 1200 + + ++ +R+R + EL+ +R+ L Sbjct: 529 MEADER----DRKREKEELEEIRQRL 550 >gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] Length = 2817 Score = 92.8 bits (229), Expect = 2e-18 Identities = 99/381 (25%), Positives = 161/381 (42%), Gaps = 61/381 (16%) Query: 329 ERLQMDEELR---REREREREREREREADREREKEREREREKEREQEKEREREKEREREL 385 E+ EE+R RE+ERERE+E E+E ++EREKERE++RE+++E+EKE E+E+E++RE+ Sbjct: 496 EKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREM 555 Query: 386 ERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTP--------TRA 437 E++R+Q +EKEL K E + E +ER K E++ P Sbjct: 556 EKERKQE-KEKELERQKEKEKELQKMKE-QEKECELEKEREKLEEKIEPREPNLEPMVEK 613 Query: 438 EKLKDAGLQAPKPV-------QHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQ- 489 ++ +++ + +PV + P H T P S P + + Q Sbjct: 614 QESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQ------PRPAVLSGYFKQF 667 Query: 490 RTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRP-ESTTRP 548 + + ++ +Q +++Q++ +Q Q Q V Q PP P HRP +P Sbjct: 668 QKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPP----HRPLYQPMQP 723 Query: 549 GPNRHEPGGRDP----------PQHFGGPPP---------LISPKPQLHAAPTALWNPVS 589 P G DP P+ G P +I PKP + + + Sbjct: 724 HPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRR------DQME 777 Query: 590 LMDNTLETRRAESHSLHSHPAAFEPSRQA----AVPLVKVERVFCPEKAEEGPRKREPAP 645 N+ E+ + S H + R P + ++ P+ EE R A Sbjct: 778 GSPNSSESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAA 837 Query: 646 LDKYQPPPPPPREGGSLEHQP 666 LD+ Q E LE P Sbjct: 838 LDQEQITAAYSVEHNQLEAHP 858 Score = 39.3 bits (90), Expect = 0.023 Identities = 31/128 (24%), Positives = 58/128 (45%), Gaps = 14/128 (10%) Query: 8 PKSPSLGMLSTATRTTATVNPLTPSPLNGALVPSGSPATSSALSAQAAPSSSFAAALRKL 67 P SP + ++A+ + + + + + + P+ +PA + L++ + P A++ L Sbjct: 1802 PASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTP-----ASVTIL 1856 Query: 68 AKQAEEPRGSSLSSESSPVSSPATNHSSPA-------STPKRVPMGPIIVPPGGHSVPST 120 A + S+L+S S+P +PA SSPA + P P + + P S P+ Sbjct: 1857 ASASIPILASALASTSAPTPAPAA--SSPAAPVITAPTIPASAPTASVPLAPASASAPAP 1914 Query: 121 PPVVTIAP 128 P AP Sbjct: 1915 APTPVSAP 1922 Score = 38.9 bits (89), Expect = 0.030 Identities = 59/257 (22%), Positives = 91/257 (35%), Gaps = 24/257 (9%) Query: 2 KGMSHEPKSPSLGMLSTAT-----RTTATVNPLTPSPLNGALVPSGSPATSSALSAQAAP 56 KG S K P AT +++A+V PL +PL + S +TS+ L A P Sbjct: 1717 KGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTP 1776 Query: 57 SSSFAAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHS 116 + +A + A +S +SP++ + + S AS P I S Sbjct: 1777 VPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPAS 1836 Query: 117 VPSTPPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQEKAGGPA----- 171 P+ P++ T + S S S +S P P A PA Sbjct: 1837 APAPTPILASVSTPASVTILASASIPILASALAS-------TSAPTPAPAASSPAAPVIT 1889 Query: 172 ---IPSHLLSTPYPFGLSPSSVVQDSRFP-PLNLQRPVHHVVPPSTVTEDYLRSFRPYHT 227 IP+ + P L+P+S + P P++ P P T + + P T Sbjct: 1890 APTIPASAPTASVP--LAPASASAPAPAPTPVSAPNPA-PPAPAQTQAQTHKPVQNPLQT 1946 Query: 228 TDDLRMSSLPPLGLDPA 244 T P + L A Sbjct: 1947 TSQSSKQPPPSIRLPSA 1963 Score = 37.4 bits (85), Expect = 0.088 Identities = 32/130 (24%), Positives = 59/130 (45%), Gaps = 5/130 (3%) Query: 1070 SSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAV 1129 SS PPP+ QQ PP R+ P + S+++ ++DE + +E Sbjct: 403 SSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERA 462 Query: 1130 FEAYQEHIEEQNLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERER- 1188 + +E EE+ +E Q +L+ L + +Q S E+R ++++ ERE+ Sbjct: 463 RKRREE--EERRMEEQRKAACAEKLKRLDEKLGILEKQ--PSPEEIREREREKEREREKE 518 Query: 1189 LQAELDHLRK 1198 L+ E + R+ Sbjct: 519 LEKEQEQERE 528 Score = 34.7 bits (78), Expect = 0.57 Identities = 27/119 (22%), Positives = 53/119 (44%), Gaps = 4/119 (3%) Query: 1073 RAPPPQHNGQQEPPTARKGPPTQELDRDSE-EEEEEDDEDGEDEEEVPKRKWQGIEAVFE 1131 + P P+ ++E R+ E +++ E E+E E D + + E+E K Q + E Sbjct: 497 KQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREME 556 Query: 1132 AYQEHIEEQNLERQ---VLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERE 1187 ++ +E+ LERQ + Q + + + L E+L + + MV ++E Sbjct: 557 KERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQE 615 Score = 32.7 bits (73), Expect = 2.2 Identities = 55/245 (22%), Positives = 91/245 (37%), Gaps = 41/245 (16%) Query: 461 PHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQRRLR------QEKEDRQSQ 514 PHHT + + F P +A +R + E +R+R + Q+ ++++S+ Sbjct: 884 PHHTDAN--NQSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSE 941 Query: 515 VSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRP--GPNRHEPGGRDPPQHFGGPPPLIS 572 S +V + +D P E + + E R GP + E + + GP P + Sbjct: 942 PSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGP-KPEKVYKSKSETRWGPRPSSN 1000 Query: 573 PKPQLHAAPTALWNPVSL-----MDNTLETRRAESHSLHSHPAAFEPSRQAAVPLVKVER 627 + +++ P P+ M E R+ + K E+ Sbjct: 1001 RREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGE-------------------KAEK 1041 Query: 628 VFCPEKAEEGPRKREPAPLDKYQPPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILG 687 V EK P K E L PPPPPP + + +P P AE ST+T Sbjct: 1042 V--TEKVVVKPEKTEKKDL----PPPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTETATL 1095 Query: 688 QQRAS 692 Q+ S Sbjct: 1096 AQKPS 1100 Score = 31.6 bits (70), Expect = 4.8 Identities = 38/140 (27%), Positives = 56/140 (40%), Gaps = 25/140 (17%) Query: 711 PYRPPVPRAPDP------AYIYDEFLQQRRRLVSKLDL----------EERRRREAQEKG 754 P R VP P P DE +QRRR S++ EE RR E Q K Sbjct: 420 PDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKA 479 Query: 755 YYYDLDDSYDES--------DEEEVRAHLRCVAEQPPLKLDTSSEK-LEFLQLFGLTTQQ 805 + DE EE+R R + +L+ E+ E + QQ Sbjct: 480 ACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQ 539 Query: 806 QKEELVAQKRRKRRRMLRER 825 +KE+ + +++ K+R M +ER Sbjct: 540 EKEKELEKEQEKQREMEKER 559 Score = 31.2 bits (69), Expect = 6.3 Identities = 23/120 (19%), Positives = 52/120 (43%), Gaps = 1/120 (0%) Query: 1036 QKALQKHKGSVAVLSAEQNHKVDTSVHYNIPELQSSSRAPPPQHNGQQEPPTARKGPPTQ 1095 ++ +K + L EQ + + + Q + + Q+E RK + Sbjct: 506 EREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEK 565 Query: 1096 ELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQNLERQVLQTQCRRLE 1155 EL+R E+E+E +++E +++ + +E E + ++E +E+Q + C + E Sbjct: 566 ELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPM-VEKQESENSCNKEE 624 Score = 30.8 bits (68), Expect = 8.2 Identities = 34/140 (24%), Positives = 55/140 (39%), Gaps = 9/140 (6%) Query: 325 GLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERE 384 G E++ + R R RE DR + ++ R+ ++ERE+ KE+E E Sbjct: 978 GPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGE 1037 Query: 385 -LERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKDA 443 E+ E+ + E K L P P ++ + +P + P+ + Sbjct: 1038 KAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPS-----TET 1092 Query: 444 GLQAPKPVQ---HPLHPVPT 460 A KP Q PL PV T Sbjct: 1093 ATLAQKPSQDTEKPLEPVST 1112 >gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] Length = 1564 Score = 90.1 bits (222), Expect = 1e-17 Identities = 75/219 (34%), Positives = 109/219 (49%), Gaps = 22/219 (10%) Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKE-REREK 379 E+ L ER + + E RE+ER+RER+R+R+ DRERE+ERER+REKERE+E+E RERE+ Sbjct: 702 EKERELERERAR-EREREREKERDRERDRDRDHDRERERERERDREKEREREREERERER 760 Query: 380 ERERELERQREQ-----RAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTP 434 ERERE ER+RE+ R R+KE + E + R E+R Sbjct: 761 ERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDER 820 Query: 435 TRAEKLKDAGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEE 494 ++ ++ G +P P Q P H+ S N G + LL Q + Sbjct: 821 KSKKRYRNEG--SPSPRQSPKR---RREHSPDSDAYNSG----DDKNEKHRLLSQVVRPQ 871 Query: 495 E------KWLARQRRLRQEKEDRQSQVSEFRQQVLEQHL 527 E L R+ R ++EDR+ + E ++ EQ L Sbjct: 872 ESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQEL 910 Score = 87.0 bits (214), Expect = 1e-16 Identities = 43/74 (58%), Positives = 57/74 (77%), Gaps = 10/74 (13%) Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEK----------EREREKERER 383 + E RERER+RERE+ERE +RER +EREREREKER++E+ ERERE++RE+ Sbjct: 688 ERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREK 747 Query: 384 ELERQREQRAREKE 397 E ER+RE+R RE+E Sbjct: 748 EREREREERERERE 761 Score = 86.7 bits (213), Expect = 1e-16 Identities = 38/66 (57%), Positives = 55/66 (83%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQ 391 + + + RE+ERE ERER RE +REREKER+RER+++R+ ++ERERE+ER+RE ER+RE+ Sbjct: 694 ERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERER 753 Query: 392 RAREKE 397 RE+E Sbjct: 754 EERERE 759 Score = 85.9 bits (211), Expect = 2e-16 Identities = 43/73 (58%), Positives = 57/73 (78%), Gaps = 3/73 (4%) Query: 328 AERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELER 387 A + E RERERERERER+RE ++ERE ERER RE+ERE+EKER+RE++R+R+ +R Sbjct: 676 ARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDR 735 Query: 388 QRE---QRAREKE 397 +RE +R REKE Sbjct: 736 ERERERERDREKE 748 Score = 84.7 bits (208), Expect = 5e-16 Identities = 44/71 (61%), Positives = 53/71 (74%), Gaps = 7/71 (9%) Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQ-- 391 D R RER+RERER+RE +RERE+ER+REREKERE E+ER RE+ERERE ER RE+ Sbjct: 670 DRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDR 729 Query: 392 -----RAREKE 397 R RE+E Sbjct: 730 DRDHDRERERE 740 Score = 83.6 bits (205), Expect = 1e-15 Identities = 46/90 (51%), Positives = 61/90 (67%), Gaps = 2/90 (2%) Query: 309 ELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADRERE-KEREREREK 367 EL ER ER D + RERERERER+RE+E +RERE +ERERERE+ Sbjct: 706 ELERERAREREREREKERDRER-DRDRDHDRERERERERDREKEREREREERERERERER 764 Query: 368 EREQEKEREREKERERELERQREQRAREKE 397 ERE+E+ERERE+ RER+ ER+R++ +K+ Sbjct: 765 ERERERERERERARERDKERERQRDWEDKD 794 Score = 75.5 bits (184), Expect = 3e-13 Identities = 39/79 (49%), Positives = 54/79 (68%), Gaps = 3/79 (3%) Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERERE 378 H R L + + + + R +R ER RER+ +RER++ERERERE+ER++E+E+ERE Sbjct: 647 HQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERE 706 Query: 379 KERERELERQREQRAREKE 397 ERER ER+RE REKE Sbjct: 707 LERERARERERE---REKE 722 Score = 68.2 bits (165), Expect = 5e-11 Identities = 34/76 (44%), Positives = 54/76 (71%), Gaps = 2/76 (2%) Query: 318 LHSERMSGLSAERLQMDEELRRERERERERE--REREADREREKEREREREKEREQEKER 375 +HS S S +RLQ + +RERERER R+RE DR+ +K+ R R+++R +E+ER Sbjct: 1286 VHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERER 1345 Query: 376 EREKERERELERQREQ 391 ERE+++ R+L+R+RE+ Sbjct: 1346 ERERDKRRDLDRERER 1361 Score = 60.5 bits (145), Expect = 1e-08 Identities = 41/108 (37%), Positives = 60/108 (55%), Gaps = 7/108 (6%) Query: 305 RYPP-----ELSHSSLAALHSERMSGLSAERLQMDEELRRERERERERER-EREADRERE 358 RYP + SS H ER + ER Q R + R E ER ER +R + Sbjct: 607 RYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVD 666 Query: 359 KEREREREKEREQEKEREREKERERELERQRE-QRAREKELLAAKALE 405 + +R E+ RE+++ERER++ERERE ER+R+ +R +E+EL +A E Sbjct: 667 RVDDRRDERARERDRERERDRERERERERERDREREKERELERERARE 714 Score = 52.8 bits (125), Expect = 2e-06 Identities = 23/64 (35%), Positives = 42/64 (65%) Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393 D++ R R+R+R RERERE +R++ ++ +RERE+ ER+R+++R+R E + + Sbjct: 1328 DKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESV 1387 Query: 394 REKE 397 + E Sbjct: 1388 KRCE 1391 Score = 50.4 bits (119), Expect = 1e-05 Identities = 25/60 (41%), Positives = 39/60 (65%) Query: 339 REREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKEL 398 R+R+R RERERERE D+ R+ +RERER E++R+R+++R E + + E +L Sbjct: 1335 RDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKL 1394 Score = 43.5 bits (101), Expect = 0.001 Identities = 34/104 (32%), Positives = 53/104 (50%), Gaps = 25/104 (24%) Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERE-- 376 HS R S ++R Q+ R+R +ER+R E +RERE+ER ++RE Sbjct: 1273 HSSRRSSPESDR-QVHSRSGSFDSRDRLQERDRY-------EHDRERERERRDTRQREWD 1324 Query: 377 ------------REKERERELERQREQRA---REKELLAAKALE 405 R++ RERE ER+R++R RE+E L + ++E Sbjct: 1325 RDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVE 1368 Score = 40.8 bits (94), Expect = 0.008 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 10/119 (8%) Query: 276 LRSPFYPIPTPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDE 335 LR P P+ P + H S +R H ER S R + E Sbjct: 367 LRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDH--------ERTSQSHDRRHERRE 418 Query: 336 ELRREREREREREREREADREREKEREREREKEREQEKERE--REKERERELERQREQR 392 + R +R+RE++ ERE ++++ R+ ++E ++R R+ REL R+ R Sbjct: 419 DTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMR 477 Score = 37.4 bits (85), Expect = 0.088 Identities = 105/514 (20%), Positives = 184/514 (35%), Gaps = 75/514 (14%) Query: 338 RRERERE----REREREREADREREKEREREREKEREQEKEREREKERERE---LERQRE 390 RR ER RER + + D + E ++ E KE R + RE+E + ++R Sbjct: 75 RRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERT 134 Query: 391 QRAREKELLAAKALEPS--------FLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKD 442 + E+ + + S ++ L R E K EQ + E++ Sbjct: 135 PESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMK-LEQENMEKREEIII 193 Query: 443 AGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQR 502 +P+ V+ L P P+ + S S P SS+A+ + + L +QR Sbjct: 194 KKEVSPEVVRSKLSPSPSLRKSSKSPKRK----SSPKSSSASKKDRKTSAVSSPLLDQQR 249 Query: 503 RLRQEKEDRQSQVSEFRQQVLEQHLDMGRP-PVPAEAEHRPESTTRPGPNRHEPGGRD-- 559 + + ++ + + + + +G+ + + R E TR G +R GRD Sbjct: 250 NSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDR----GRDFE 305 Query: 560 PPQHFGGPPPLISPKPQLHAAPTALWNPVSLMDNTLETRRAESHSLHSHPAAFEPS-RQA 618 + P SP Q H +P+S ++ ++ S HS PS R+ Sbjct: 306 RQREKRDKPRSTSPAGQHH-------SPISSRHHSSSSQSGSSIQRHS------PSPRRK 352 Query: 619 AVPLVKVERVFCP---EKAEEGPRKREPAPLDKYQPP--PPPPREGGSLEHQPFLPGPGP 673 P +R P A P +P K PP P RE G +H+ Sbjct: 353 RTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHE-------- 404 Query: 674 FLAELEKSTQTILGQQRASLPQAATFGELSGPLKPGSPYRPPVPRAPDPAYIYDEFLQQR 733 +T R + T G+ R + + + R Sbjct: 405 ---------RTSQSHDRRHERREDTRGK-----------RDREKDSREEREYEQDQSSSR 444 Query: 734 RRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAE-QPPLKLDTSSEK 792 + + R RR+A++ +L DS D D E+R + R E + P ++ + Sbjct: 445 DHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDA 504 Query: 793 LEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERS 826 ++ G T ++++ + R R LRE S Sbjct: 505 HDYRDREGRDTHRKEDTYPEESRSYGRNHLREES 538 Score = 33.1 bits (74), Expect = 1.7 Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 3/56 (5%) Query: 338 RREREREREREREREADREREKEREREREKEREQEKER---EREKERERELERQRE 390 R++ R E+DR+ ++R QE++R +RE+ERER RQRE Sbjct: 1267 RQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQRE 1322 Score = 31.2 bits (69), Expect = 6.3 Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 25/114 (21%) Query: 308 PELSHSSLAALHSERMSGLSAERLQMDEELRRERERERERERERE-ADREREKERERERE 366 PEL ++ S+ D R ER+R ER+ D+ R+ ER R Sbjct: 568 PELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFER-RH 626 Query: 367 KEREQEKEREREKE---------RERELER--------------QREQRAREKE 397 ER++ RER++ R ELER +R++RARE++ Sbjct: 627 GERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERD 680 Score = 31.2 bits (69), Expect = 6.3 Identities = 30/126 (23%), Positives = 55/126 (43%), Gaps = 10/126 (7%) Query: 326 LSAERLQMDEELR-RERERERER-EREREADREREKEREREREKEREQEKEREREKERER 383 LS L D + R +E +R+ ER E R + + KE+ +K+REQ + E + R + Sbjct: 876 LSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQ 935 Query: 384 EL-------ERQREQRAREKELLAAKALEPSFLPVAELH-GLRGHATEERGKPSEQLTPT 435 ++ +R+ RA ++ AK + E G+ E + + +P Sbjct: 936 DIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPK 995 Query: 436 RAEKLK 441 + +K K Sbjct: 996 KGQKKK 1001 Score = 31.2 bits (69), Expect = 6.3 Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 5/66 (7%) Query: 23 TATVNPLTPSPLNGALVPSGSPATSSALSAQAAPSSSFAAALRKLAKQAEEPRGSSLSSE 82 TAT TPSPL+ L P AT++A + A +++ AAA + A ++S+ Sbjct: 1086 TATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSA-----ITISTS 1140 Query: 83 SSPVSS 88 ++P ++ Sbjct: 1141 ATPTNT 1146 >gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo sapiens] Length = 600 Score = 86.3 bits (212), Expect = 2e-16 Identities = 42/69 (60%), Positives = 56/69 (81%), Gaps = 1/69 (1%) Query: 330 RLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQR 389 R + D E R+RER+RERERERE +R+RE+ERERERE+ER++E ER+REKERER+ +RQ Sbjct: 290 RTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQT 349 Query: 390 E-QRAREKE 397 E R R ++ Sbjct: 350 EMDRERNRQ 358 Score = 81.3 bits (199), Expect = 5e-15 Identities = 38/79 (48%), Positives = 58/79 (73%), Gaps = 1/79 (1%) Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERERE 378 HSER ER + + E R+R+ +RER+R+R+ +REREK+ ERER ERE E+++ERE Sbjct: 205 HSERGRERERER-ETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE 263 Query: 379 KERERELERQREQRAREKE 397 +ER+R+ +R R Q+ RE++ Sbjct: 264 RERDRDRDRDRRQKERERQ 282 Score = 81.3 bits (199), Expect = 5e-15 Identities = 40/77 (51%), Positives = 58/77 (75%), Gaps = 1/77 (1%) Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380 ER +R Q + E + +R+R+R ER+RE +R+RE++RERERE+ER +++ERERE+E Sbjct: 265 ERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERE 324 Query: 381 RERELERQREQRAREKE 397 RERE +R+ E R REKE Sbjct: 325 RERERQRETE-RDREKE 340 Score = 78.6 bits (192), Expect = 3e-14 Identities = 35/65 (53%), Positives = 51/65 (78%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQ 391 Q D + +R ER+RE ER+RE RERE+ERER R++ERE+E+ERERE++RE E +R++E+ Sbjct: 282 QTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKER 341 Query: 392 RAREK 396 + K Sbjct: 342 ERKRK 346 Score = 76.6 bits (187), Expect = 1e-13 Identities = 51/119 (42%), Positives = 69/119 (57%), Gaps = 15/119 (12%) Query: 321 ERMSGLSAERLQMDEELRRERERERER-----EREREADR------EREKEREREREKER 369 ER S ER D+E RER+R+R+R ERER+ DR ER++E ER+RE++R Sbjct: 249 ERASERETER---DKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQR 305 Query: 370 EQEKEREREKERERELERQRE-QRAREKELLAAKALEPSFLPVAELHGLRGHATEERGK 427 E+E+ERER ++RERE ER+RE +R RE E K E E+ R T G+ Sbjct: 306 ERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGR 364 Score = 76.3 bits (186), Expect = 2e-13 Identities = 40/90 (44%), Positives = 56/90 (62%), Gaps = 24/90 (26%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQ-------------------- 371 Q + E RER R+RERERERE +RER++E ER+REKERE+ Sbjct: 304 QRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG 363 Query: 372 ----EKEREREKERERELERQREQRAREKE 397 E+ERERE+ER+R+ R+RE+R R+++ Sbjct: 364 RRQAERERERERERDRQSAREREERERDRD 393 Score = 75.1 bits (183), Expect = 4e-13 Identities = 45/118 (38%), Positives = 67/118 (56%), Gaps = 7/118 (5%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEK------EREREKEREREL 385 Q D + RER+R+ E+ERER+ DRER+++ ER R+KERE+EK ERER++E+E + Sbjct: 142 QTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKT 201 Query: 386 ERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATE-ERGKPSEQLTPTRAEKLKD 442 E + +R RE+E E + R TE ER K +E+ + E +D Sbjct: 202 EDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERD 259 Score = 74.3 bits (181), Expect = 6e-13 Identities = 42/94 (44%), Positives = 59/94 (62%), Gaps = 17/94 (18%) Query: 329 ERLQMDEELRREREREREREREREADREREKERERE--------REKEREQEKEREREKE 380 E+ Q + E R+RER RE++R R+ DR RE++R+RE RE++R++EKER R+KE Sbjct: 67 EKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKE 126 Query: 381 RERELERQRE---------QRAREKELLAAKALE 405 RERE ER+ E QR RE++ A K E Sbjct: 127 RERETEREGERGRDRQTDGQRERERQRDAEKERE 160 Score = 73.6 bits (179), Expect = 1e-12 Identities = 36/71 (50%), Positives = 51/71 (71%), Gaps = 5/71 (7%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQ--- 388 + E RERER R+RERERE +RERE++RE ER++E+E+E++R+R+ E +RE RQ Sbjct: 302 ERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGR 361 Query: 389 --REQRAREKE 397 R Q RE+E Sbjct: 362 EGRRQAERERE 372 Score = 73.2 bits (178), Expect = 1e-12 Identities = 34/78 (43%), Positives = 57/78 (73%), Gaps = 1/78 (1%) Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380 +R ER + E+ + ERE +R+RER RE DR R+++R RER+++RE+E+ER+ ++E Sbjct: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112 Query: 381 RERELERQR-EQRAREKE 397 R+R+ E++R Q+ RE+E Sbjct: 113 RDRQREKERNRQKERERE 130 Score = 72.0 bits (175), Expect = 3e-12 Identities = 38/83 (45%), Positives = 60/83 (72%), Gaps = 7/83 (8%) Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERE---- 376 ER + ER + + R+R+R+ ERERE++A+RER ERE ER+KERE+E++R+ Sbjct: 215 ERETETETERKRQTDR-ERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD 273 Query: 377 -REKERERELERQREQRA-REKE 397 R+KERER+ +R+R++R R++E Sbjct: 274 RRQKERERQTDRKRQRRTERDRE 296 Score = 72.0 bits (175), Expect = 3e-12 Identities = 35/67 (52%), Positives = 53/67 (79%), Gaps = 2/67 (2%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQRE- 390 Q + E ERE ER++ERERE DR+R+++R R++E+ER+ +++R+R ER+RE ER+RE Sbjct: 245 QAERERASERETERDKERERERDRDRDRDR-RQKERERQTDRKRQRRTERDRETERKRER 303 Query: 391 QRAREKE 397 QR RE+E Sbjct: 304 QRERERE 310 Score = 71.6 bits (174), Expect = 4e-12 Identities = 43/88 (48%), Positives = 61/88 (69%), Gaps = 11/88 (12%) Query: 320 SERMSGLSAERLQMDE-ELRREREREREREREREADREREKERERER--------EKERE 370 +ER AER + E E R++ERERER+R+R+ DR R+KERER+ E++RE Sbjct: 238 TEREREKQAERERASERETERDKERERERDRDRDRDR-RQKERERQTDRKRQRRTERDRE 296 Query: 371 QEKEREREKERERELERQRE-QRAREKE 397 E++RER++ERERE ER R+ +R RE+E Sbjct: 297 TERKRERQRERERERERNRKRERERERE 324 Score = 70.9 bits (172), Expect = 7e-12 Identities = 34/79 (43%), Positives = 56/79 (70%), Gaps = 1/79 (1%) Query: 320 SERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREK 379 +ER ER + R ERER+R+R+R++E +R+ EK+R+ +RE E+++E+E++RE Sbjct: 367 AERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRES 426 Query: 380 ERERELERQRE-QRAREKE 397 ER RE R+RE Q+ RE++ Sbjct: 427 ERGRERGREREKQKGRERD 445 Score = 70.5 bits (171), Expect = 9e-12 Identities = 50/144 (34%), Positives = 73/144 (50%), Gaps = 28/144 (19%) Query: 319 HSERMSGLSAER-LQMDEELRREREREREREREREAD----------------REREKER 361 H ER ER Q D E R+RE+ER R++ERE + RERE++R Sbjct: 94 HRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR 153 Query: 362 EREREKEREQEKEREREKERERELERQRE---QRAREKELLAAKALEPSFLPVAELHGLR 418 + E+E+ER+ ++ER+R+ ER R+ ER+RE Q RE+E K + + H R Sbjct: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK-----TEDRHSER 208 Query: 419 GHATEERGKPSEQLTPTRAEKLKD 442 G ER + E T T ++ D Sbjct: 209 G---RERERERETETETERKRQTD 229 Score = 70.5 bits (171), Expect = 9e-12 Identities = 42/99 (42%), Positives = 56/99 (56%), Gaps = 23/99 (23%) Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKERERER--------------- 365 ER ER + + + RERERERERER+RE +R+REKERER+R Sbjct: 302 ERQRERERER-ERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTG 360 Query: 366 -------EKEREQEKEREREKERERELERQREQRAREKE 397 E+ERE+E+ER+R+ RERE + R R+KE Sbjct: 361 REGRRQAERERERERERDRQSAREREERERDRDRDRQKE 399 Score = 70.5 bits (171), Expect = 9e-12 Identities = 41/77 (53%), Positives = 53/77 (68%), Gaps = 10/77 (12%) Query: 330 RLQMDEELRRERERERE-----REREREADREREKEREREREKER----EQEKEREREKE 380 R Q + E RERER+R+ ERER+ DR+R+KERER+ EK+R E EK+REREK+ Sbjct: 364 RRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKD 423 Query: 381 RERELERQREQRAREKE 397 RE E R+R R REK+ Sbjct: 424 RESERGRER-GREREKQ 439 Score = 70.1 bits (170), Expect = 1e-11 Identities = 37/91 (40%), Positives = 61/91 (67%), Gaps = 1/91 (1%) Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380 ER + ER + + + R+R++ERER+ E++ D +RE E++REREK+RE E+ RER +E Sbjct: 376 ERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRE 435 Query: 381 RERELERQREQRAREKELLAAKALEPSFLPV 411 RE++ R+R+ R R+ + A + + S L V Sbjct: 436 REKQKGRERD-RERQTDRQAGRQRKRSTLYV 465 Score = 69.7 bits (169), Expect = 2e-11 Identities = 40/83 (48%), Positives = 53/83 (63%), Gaps = 14/83 (16%) Query: 329 ERLQMDEELRRERERERERERE------------READREREKEREREREKEREQ--EKE 374 E+ E+ ER RERERERE RE DR+R+ ERERE++ ERE+ E+E Sbjct: 196 EKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERE 255 Query: 375 REREKERERELERQREQRAREKE 397 ER+KERERE +R R++ R+KE Sbjct: 256 TERDKERERERDRDRDRDRRQKE 278 Score = 69.3 bits (168), Expect = 2e-11 Identities = 66/236 (27%), Positives = 100/236 (42%), Gaps = 54/236 (22%) Query: 325 GLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERE 384 G ER + E RR +R+ ERE +R+ +R REK+R R+R++ R E++R+REKERER+ Sbjct: 51 GDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHR--ERQRDREKERERQ 108 Query: 385 LERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKDAG 444 +R+R+ R REKE K E E G RG + G+ E+ +DA Sbjct: 109 TDRERD-RQREKERNRQKERERE----TEREGERGRDRQTDGQ-------RERERQRDAE 156 Query: 445 LQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQR-R 503 + + QR E + R+R + Sbjct: 157 KERERQTDRER---------------------------------QRQTERNRQKEREREK 183 Query: 504 LRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRD 559 RQE+ +R+ Q E + ++H + GR E E E+ T R RD Sbjct: 184 NRQERRERERQ-REKENKTEDRHSERGR-----ERERERETETETERKRQTDRERD 233 Score = 68.6 bits (166), Expect = 4e-11 Identities = 42/104 (40%), Positives = 60/104 (57%), Gaps = 19/104 (18%) Query: 321 ERMSGLSAER-LQMDEELRREREREREREREREADREREKEREREREKE----------- 368 ER ER Q D E +R+ ER R++ERERE +R+ +ERER+REKE Sbjct: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERG 209 Query: 369 --REQEKEREREKERERELERQRE-----QRAREKELLAAKALE 405 RE+E+E E E ER+R+ +R+R+ +R REK+ +A E Sbjct: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253 Score = 67.0 bits (162), Expect = 1e-10 Identities = 38/89 (42%), Positives = 62/89 (69%), Gaps = 5/89 (5%) Query: 320 SERMSGLSAERLQMDEELRRERERERERE---REREADREREKEREREREKEREQEKERE 376 +ER ER + +E RRERER+RE+E +R ++R RE+ERERE E E E++++ + Sbjct: 171 TERNRQKEREREKNRQE-RRERERQREKENKTEDRHSERGRERERERETETETERKRQTD 229 Query: 377 REKERERELERQREQRAREKELLAAKALE 405 RE++R+R+ ER+RE++A E+E + + E Sbjct: 230 RERDRQRKTEREREKQA-ERERASERETE 257 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 81.3 bits (199), Expect = 5e-15 Identities = 178/852 (20%), Positives = 305/852 (35%), Gaps = 172/852 (20%) Query: 336 ELRREREREREREREREADREREKEREREREKEREQEKEREREKER--ERELERQREQRA 393 EL++E ++R+ E+E+ A +++ E + +R+KE ++ +RE+ R R R R Sbjct: 125 ELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRR 184 Query: 394 REKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKDAGLQ------- 446 R + + S P E+ + + +L P + K+K+ +Q Sbjct: 185 RSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPEL-PEPSVKVKEPSVQEATSTSD 243 Query: 447 ---APKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQRR 503 PKP P+P P P S ++ E+EK R R Sbjct: 244 ILKVPKP-----EPIPEPKEPSPEKNS------------------KKEKEKEKTRPRSRS 280 Query: 504 LRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQH 563 R + R S + +H R P RP RP P R R PP+ Sbjct: 281 -RSKSRSRTRSRSPSHTRPRRRHRSRSRSYSP---RRRPSPRRRPSPRR-----RTPPRR 331 Query: 564 FGGPPPLISPKPQLHAAPTALWNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAAVPLV 623 PPP P+ + +P + RR S SL ++ SR + P Sbjct: 332 M--PPP---PRHRRSRSP-------------VRRRRRSSASLSGSSSSSSSSRSRSPPKK 373 Query: 624 KVERVFCPEKAEEGPRKREPAPLDKYQPPP---PPPREGGSLEHQPFLPGPGPFLAELEK 680 +R P + P +++P P PPP+ S P P ++ Sbjct: 374 PPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHS-------PTP-------QQ 419 Query: 681 STQTILGQQRASLPQAATFGELS---GPLKPGSPYRPPVPRAPDPAYIYDEFLQQRRRLV 737 S +T + R S+ T G+++ G K SP P PR + + + + ++ Sbjct: 420 SNRT--RKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVE---LSESEEDKGGKMA 474 Query: 738 SKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHL--------------RCVAEQP- 782 + +++RR+ Q + D S DE R+H+ R + P Sbjct: 475 AADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR 534 Query: 783 PLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRML---RERSPSPPTIQSKRQTP 839 + +TS T++++ A R+RR R R+PSPP +R++P Sbjct: 535 KRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPP---PRRRSP 591 Query: 840 SPRL---ALSTRYSPD--------------EMNNSPNFEEKKKFLTIFNLTHISAEKRKD 882 SPR + RYSP + SP+ K++ ++H K++ Sbjct: 592 SPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRR------VSHSPPPKQRS 645 Query: 883 K---ERLVEMLRAMKQKALSAAVADSLTNSP----RDSPAVSLSEPATQQASLDV----- 930 +R L + +K S + + SP R SP+ P T + V Sbjct: 646 SPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGAS 705 Query: 931 ------EKPVGVAASLSDIPKAAEPGKLEQV---RPQELSRVQELAPASGEKARLSEAPG 981 + P + + + EP K+++ PQ + RV SG S P Sbjct: 706 SSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSG-----SPEPA 760 Query: 982 GKKSLSMLHYIRGAAPK---DIPVPLSHSTNGKSKPWEPFVA-EEFAHQFHESVLQSTQK 1037 KK + ++ +P VP+ + + P P + +E + + K Sbjct: 761 AKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHK 820 Query: 1038 ALQKHKGSVAVLSAEQNHKVDTSVHYNIPELQSSSRAPPPQHNGQQEPPTARKGPPTQEL 1097 +KHK + HK + +V + + QE P A P + Sbjct: 821 KDKKHK-------KHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVA---APEPKK 870 Query: 1098 DRDSEEEEEEDD 1109 + +SE E+ DD Sbjct: 871 ETESEAEDNLDD 882 Score = 37.7 bits (86), Expect = 0.067 Identities = 44/188 (23%), Positives = 63/188 (33%), Gaps = 25/188 (13%) Query: 31 PSPLNGALVPSGSPATSSALSAQAAPSSSFAAALRKLAKQAEEPRGSSLSSESSPVSSPA 90 P P PS P + S SS R + ++ +GSS S + SP Sbjct: 618 PPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQ 677 Query: 91 TNHSSPASTPKRVPMGPIIVPPGGHSV-----------PSTPPVVTIAPTKTVNGVWRSE 139 N S R P PP PST P+ ++ T + ++ Sbjct: 678 PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAA 737 Query: 140 S------RQDAGSRSSSGGRERLIVEPPLPQEKA--------GGPAIPSHLLSTPYPFGL 185 S R+ + SRS SG E +PP P PA+P +P P Sbjct: 738 SPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPS 797 Query: 186 SPSSVVQD 193 P + Q+ Sbjct: 798 PPRNSDQE 805 Score = 37.4 bits (85), Expect = 0.088 Identities = 83/402 (20%), Positives = 139/402 (34%), Gaps = 73/402 (18%) Query: 55 APSSSFAAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTP----KRVPMGPIIV 110 +PS S + + RK K+ PRG S S P P SP+ P +R P Sbjct: 524 SPSRSASPSPRKRQKETS-PRGRRRRSPSPP---PTRRRRSPSPAPPPRRRRTP-----T 574 Query: 111 PPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQEKAGGP 170 PP PS PP + + R S S S +R PP P ++ P Sbjct: 575 PPPRRRTPSPPP-------RRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASP 627 Query: 171 AIP----------------------SHLLSTPYPFGLSPSSVVQDSRFPPLNLQRPVHHV 208 + P S LS+ + G SPS +++R P N +R Sbjct: 628 SPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPN-KRHSPSP 686 Query: 209 VPPSTVTEDYLRSFRPYHTTDDLRMSSLPPLGLDPATAAAYYHPSYL--APHPFPHPAFR 266 P + T R ++ R S P + P + A P P R Sbjct: 687 RPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR 746 Query: 267 MDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLHLSGVRYPPEL--------SHSSLAAL 318 + S +S P PP PS + + P + + S Sbjct: 747 VSSSRSVSGSPEP------AAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPR 800 Query: 319 HSERMSGLSAERLQMDEELRRERERERERERERE-------------ADREREKERERER 365 +S++ G ++ + D++ +++++ ++ ++ ++E A + Sbjct: 801 NSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQE 860 Query: 366 EKEREQEKEREREKERERELERQREQRAREKELLAAKALEPS 407 E E ++E E E E L+ E+ REK L + + + S Sbjct: 861 EPVAAPEPKKETESEAEDNLD-DLEKHLREKALRSMRKAQVS 901 >gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] Length = 202 Score = 79.0 bits (193), Expect = 3e-14 Identities = 35/73 (47%), Positives = 54/73 (73%) Query: 320 SERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREK 379 +ER ER E R R+R+R RER+R+ DRE+E+ER++ER+++R++E+E ERE Sbjct: 17 TERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERET 76 Query: 380 ERERELERQREQR 392 ER+RE +RQRE++ Sbjct: 77 ERQRERQRQRERK 89 Score = 75.5 bits (184), Expect = 3e-13 Identities = 37/79 (46%), Positives = 58/79 (73%), Gaps = 13/79 (16%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKE------------REQEKEREREK 379 + + E R+RER+R+RER+R+ DRER+K+R+RER++E RE++K+ ERE+ Sbjct: 71 ETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERER 130 Query: 380 ERERELERQRE-QRAREKE 397 +RERE +RQRE +R R++E Sbjct: 131 DRERERQRQRERERQRQRE 149 Score = 75.1 bits (183), Expect = 4e-13 Identities = 41/83 (49%), Positives = 61/83 (73%), Gaps = 6/83 (7%) Query: 320 SERMSGLSAERLQMDEELR---REREREREREREREADREREKERE--REREKEREQEKE 374 +ER + ER + E R RER+++R+RER+RE DR RE+ R+ RER+K+ E+E++ Sbjct: 72 TERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERD 131 Query: 375 REREKERERELERQREQRAREKE 397 RERE++R+RE ERQR QR R++E Sbjct: 132 RERERQRQRERERQR-QRERKRE 153 Score = 73.6 bits (179), Expect = 1e-12 Identities = 32/66 (48%), Positives = 54/66 (81%), Gaps = 1/66 (1%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQRE- 390 Q D E RER++ER+R+R+RE + ERE ER+RER+++RE++++ +RE++++R+ ER+RE Sbjct: 49 QTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRET 108 Query: 391 QRAREK 396 R RE+ Sbjct: 109 DRNRER 114 Score = 73.2 bits (178), Expect = 1e-12 Identities = 30/61 (49%), Positives = 50/61 (81%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQ 391 + D + RE+ERER++ER+R+ RERE ERE ER++ER++++ER+R+ +RER+ +R RE+ Sbjct: 45 ERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRER 104 Query: 392 R 392 + Sbjct: 105 K 105 Score = 72.4 bits (176), Expect = 2e-12 Identities = 33/84 (39%), Positives = 61/84 (72%), Gaps = 6/84 (7%) Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERERE 378 H ER E+ + + + R+R+R+RERE ERE +R+RE++R+RER+++ ++E++++R+ Sbjct: 43 HRERDRQTDREK-ERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRD 101 Query: 379 KERERELERQREQ-----RAREKE 397 +ER+RE +R RE+ R R+K+ Sbjct: 102 RERKRETDRNRERNRKGGRERDKQ 125 Score = 72.0 bits (175), Expect = 3e-12 Identities = 39/75 (52%), Positives = 55/75 (73%), Gaps = 12/75 (16%) Query: 335 EELRRERERERERE-------REREADREREKEREREREKEREQEKEREREKEREREL-- 385 +E RER+R+RERE R R+ DR RE++R+ +REKERE++KER+R+++RERE Sbjct: 15 KETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETER 74 Query: 386 --ERQRE-QRAREKE 397 ERQRE QR RE++ Sbjct: 75 ETERQRERQRQRERK 89 Score = 72.0 bits (175), Expect = 3e-12 Identities = 31/66 (46%), Positives = 56/66 (84%), Gaps = 1/66 (1%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQ 391 + D++ RER+RERER+R+RE +R+R++ER+RE ++ER++ ERE E+++ER+ ER++E+ Sbjct: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE-ERKKERKKERKKER 179 Query: 392 RAREKE 397 + ++KE Sbjct: 180 KEKKKE 185 Score = 71.2 bits (173), Expect = 5e-12 Identities = 30/64 (46%), Positives = 51/64 (79%) Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393 + E R+ RER+++ ERE DRERE++R+RERE++R++E++RE ++ER+R ER+ ++ Sbjct: 111 NRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKE 170 Query: 394 REKE 397 R+KE Sbjct: 171 RKKE 174 Score = 70.9 bits (172), Expect = 7e-12 Identities = 32/70 (45%), Positives = 53/70 (75%), Gaps = 6/70 (8%) Query: 334 DEELRRERERERER------EREREADREREKEREREREKEREQEKEREREKERERELER 387 D E +RE +R RER ER+++ +RER++ERER+R++ERE++++RER++E +RE +R Sbjct: 101 DRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQR 160 Query: 388 QREQRAREKE 397 E+ R+KE Sbjct: 161 WAEREERKKE 170 Score = 70.1 bits (170), Expect = 1e-11 Identities = 36/80 (45%), Positives = 55/80 (68%), Gaps = 4/80 (5%) Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380 ER ER D + R+RE +R RER R+ RER+K+ ERER++ERE++++RERE++ Sbjct: 87 ERKRQTDRER-DKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQ 145 Query: 381 RERELERQRE---QRAREKE 397 R+RE +R+ + QR E+E Sbjct: 146 RQRERKRETDRERQRWAERE 165 Score = 68.9 bits (167), Expect = 3e-11 Identities = 33/74 (44%), Positives = 54/74 (72%), Gaps = 8/74 (10%) Query: 332 QMDEELRREREREREREREREADRE---REKEREREREKEREQEKEREREKERERELERQ 388 + D ERER+R+RERE + +RE R+++R RER+++ ++EKERER+KER+R+ +R+ Sbjct: 10 ETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRE 69 Query: 389 RE-----QRAREKE 397 RE +R RE++ Sbjct: 70 RETERETERQRERQ 83 Score = 68.6 bits (166), Expect = 4e-11 Identities = 28/66 (42%), Positives = 51/66 (77%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQ 391 + D R R+ RER+++ E +R+RE+ER+R+RE+ER++++ER+RE +RER+ +RE+ Sbjct: 107 ETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREE 166 Query: 392 RAREKE 397 R +E++ Sbjct: 167 RKKERK 172 Score = 68.2 bits (165), Expect = 5e-11 Identities = 30/79 (37%), Positives = 59/79 (74%), Gaps = 1/79 (1%) Query: 329 ERLQMDEELRREREREREREREREADREREKEREREREKEREQ-EKEREREKERERELER 387 ++ + + + RER+R+RERER+R+ +R+RE +RER+R ERE+ +KER++E+++ER+ ++ Sbjct: 124 KQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKK 183 Query: 388 QREQRAREKELLAAKALEP 406 + E+R +K+ + + P Sbjct: 184 KEEKRREDKKRKWGEGISP 202 Score = 67.0 bits (162), Expect = 1e-10 Identities = 34/72 (47%), Positives = 51/72 (70%), Gaps = 8/72 (11%) Query: 333 MDEELRREREREREREREREADREREKE-------REREREKEREQEKEREREKEREREL 385 M+ + R+RE +R +E ERE DR+RE+E R R+R++ RE++++ +REKERER+ Sbjct: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60 Query: 386 ERQREQRAREKE 397 ER R QR RE+E Sbjct: 61 ERDR-QRQRERE 71 Score = 66.6 bits (161), Expect = 1e-10 Identities = 29/67 (43%), Positives = 54/67 (80%), Gaps = 5/67 (7%) Query: 336 ELRREREREREREREREADREREKEREREREKEREQEKER-----EREKERERELERQRE 390 E ++ ERER+RERER+ RERE++R+RER++E ++E++R ER+KER++E +++R+ Sbjct: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERK 180 Query: 391 QRAREKE 397 ++ +E++ Sbjct: 181 EKKKEEK 187 Score = 40.0 bits (92), Expect = 0.014 Identities = 22/62 (35%), Positives = 37/62 (59%), Gaps = 8/62 (12%) Query: 321 ERMSGLSAERLQMDEELRRERERER-------EREREREADREREKEREREREKEREQEK 373 ER ER Q E +RE +RER ER++ER+ +R++E++ +++ EK RE +K Sbjct: 135 ERQRQRERER-QRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKK 193 Query: 374 ER 375 + Sbjct: 194 RK 195 >gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] Length = 953 Score = 79.0 bits (193), Expect = 3e-14 Identities = 143/661 (21%), Positives = 237/661 (35%), Gaps = 142/661 (21%) Query: 330 RLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQR 389 R+Q E RERERERERE +R+RE+ERERER++ERE+ ++RERE+ERE E +++R Sbjct: 389 RVQYTETEPYHNYRERERERERE-NRQRERERERERDRERER-RQREREREREHERDKER 446 Query: 390 EQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKDAGLQAPK 449 ++R E E AK E R H +R K E+ K+ G P+ Sbjct: 447 QRRKEEWERERAKRDEKD----------RQHRDRDREK----------EREKEKGKPKPR 486 Query: 450 PVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQRRLRQEKE 509 Q P P +A T ++R +E W RR + K+ Sbjct: 487 SPQPPSRQAEPP----------------KKEAATTGPQVKRADE---WKDPWRRSKSPKK 527 Query: 510 DRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQHFGGPPP 569 VS P A + +++ N R G Sbjct: 528 KLGVSVS----------------PSRARRRRKTSASSASASNSSRSSSRSSSYSGSG--- 568 Query: 570 LISPKPQLHAAPTALWNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAAVPLVKVERVF 629 S + + ++ + ++ S ++ R+ S S S P+ PS Sbjct: 569 --SSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPS---PS-------------- 609 Query: 630 CPEKAEEGPRKREPAPLDKYQPPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQ 689 P P+ K +P PPP + G E P P P + K+T Sbjct: 610 ------PTPSPHRPSIRTKGEPAPPPGKAG---EKSVKKPAPPPAPPQATKTT------- 653 Query: 690 RASLPQAATFGELSGPLKPGSPYRPPVPR------APDPAYIYDEFLQQRRRLVSKLDLE 743 A +P+ G+ + P R P R Y + R L Sbjct: 654 -APVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSS 712 Query: 744 ERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTT 803 + + D +D Y ++ + + + + P T EK Sbjct: 713 VSSATSSSSSAHSVDSEDMY-----ADLASPVSSASSRSPAPAQTRKEK----------G 757 Query: 804 QQQKEELVAQKRRKRRRMLR-ERSPSPPTIQSKRQTPS-PRLALSTRYSPDEMNNSPNFE 861 + +KE+ V +++RKR + +S PP Q PS P+ A P + Sbjct: 758 KSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQA-----PPGQPQQGTFVA 812 Query: 862 EKKKFLTIFNLTHISAEKRK----DKERL---------VEMLRAMKQKALSAAVADSLTN 908 K+ LT+ N +++ DK+R R + + + Sbjct: 813 HKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPE 872 Query: 909 SPRDSPAVSLSEPATQQASLDVEKPVGVAASLSDIP-KAAEPG--KLEQVRPQELSRVQE 965 R + + + PA ++ L + ++ ++ +P KA++PG + + LSR +E Sbjct: 873 RQRGQNSKAPAAPADRKRQLSPQSK--SSSKVTSVPGKASDPGAASTKSGKASTLSRREE 930 Query: 966 L 966 L Sbjct: 931 L 931 Score = 74.3 bits (181), Expect = 6e-13 Identities = 41/71 (57%), Positives = 51/71 (71%), Gaps = 2/71 (2%) Query: 329 ERLQMDEELRRERERERERERERE-ADREREKEREREREKEREQEKER-EREKERERELE 386 ER + E +RERERERER+RERE RERE+ERE ER+KER++ KE ERE+ + E + Sbjct: 405 ERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKD 464 Query: 387 RQREQRAREKE 397 RQ R REKE Sbjct: 465 RQHRDRDREKE 475 Score = 60.8 bits (146), Expect = 7e-09 Identities = 34/60 (56%), Positives = 43/60 (71%), Gaps = 4/60 (6%) Query: 329 ERLQMDEELRREREREREREREREADREREKER-EREREKERE---QEKEREREKERERE 384 ER + E RR+RERERERE ER+ +R+R KE ERER K E Q ++R+REKERE+E Sbjct: 420 ERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKE 479 Score = 58.9 bits (141), Expect = 3e-08 Identities = 86/392 (21%), Positives = 140/392 (35%), Gaps = 49/392 (12%) Query: 321 ERMSGLSAERLQMDEELRREREREREREREREA-DREREKERERERE-KEREQEKERERE 378 ER ER Q + E RE ER++ER+R +E +RER K E++R+ ++R++EKERE+E Sbjct: 420 ERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKE 479 Query: 379 KERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAE 438 K + + Q R E A P E + + K ++P+RA Sbjct: 480 KGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRAR 539 Query: 439 KLKDAGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWL 498 + + + + + S S G S S++ + R++ + Sbjct: 540 RRRKTSASSASASN------SSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFS 593 Query: 499 ARQRRLR--QEKEDRQSQVSEFRQQVLEQHLDMGRP----------PVPAEAEHRPESTT 546 + R R S R + + P P P A + TT Sbjct: 594 GSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTT 653 Query: 547 RPGPNRHEPGGRDPPQHFGGPPPLISPKPQLHAAPTALWNPVSLMDNTLETR-------- 598 P P +PG DP + P +P + + + + S ++ +R Sbjct: 654 APVPEPTKPG--DPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVS 711 Query: 599 -----RAESHSLHS-----------HPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKRE 642 + S S HS P + SR A + E+ K E+G ++ + Sbjct: 712 SVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEK--GKSKKEDGVKEEK 769 Query: 643 PAPLDKYQPP-PPPPREGGSLEHQPFLPGPGP 673 QPP P GG QP P P Sbjct: 770 RKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAP 801 Score = 58.5 bits (140), Expect = 4e-08 Identities = 29/64 (45%), Positives = 46/64 (71%), Gaps = 2/64 (3%) Query: 329 ERLQMDEELRREREREREREREREADREREKERER-EREKEREQEKEREREKERERELER 387 ER + + R R+RERERERE E D+ER++ +E ERE+ + EK+R+ ++R+RE ER Sbjct: 418 ERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQ-HRDRDREKER 476 Query: 388 QREQ 391 ++E+ Sbjct: 477 EKEK 480 Score = 31.2 bits (69), Expect = 6.3 Identities = 78/390 (20%), Positives = 141/390 (36%), Gaps = 43/390 (11%) Query: 731 QQRRRLVSKLDLEERRRREA--QEKGYYYDLDDSYDESDEEEVRAHLRCVAEQPPLKLDT 788 ++ R + D E +RR+E +E+ + D + + D E+ R + + P Sbjct: 433 EREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEK--GKPKPRSPQP 490 Query: 789 SSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRER------SPSPPTIQSKRQTPSPR 842 S + E + TT Q + K RR ++ SPS + K S Sbjct: 491 PSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSAS 550 Query: 843 LALSTRYSPDEMNNSPNFEEKKKFLTIFNLTHISAEKRKDKERLVEMLRAMKQKALSAAV 902 + S+R S + S + + + + ++ S R + R+ + ++ S++ Sbjct: 551 ASNSSRSSSRSSSYSGSGSSRSRSRSS---SYSSYSSRSSRHSSFSGSRS-RSRSFSSSP 606 Query: 903 ADSLTNSPRDSPAVSLSEPAT---QQASLDVEKPVGVAA------SLSDIPKAAEPGKLE 953 + S T SP + EPA + V+KP A + + +P+ +PG Sbjct: 607 SPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPR 666 Query: 954 QVRPQELS------RVQELAPASGEKARLSEAPGGKKSLSMLHYIRGAAPKDIPVPLSHS 1007 + R +E R SG + S + +SLS+ ++ + S S Sbjct: 667 EARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSV------SSVSSVSSATSSS 720 Query: 1008 TNGKSKPWEPFVAEEFAHQFHESVLQSTQKALQKHKGSVAVLSA--EQNHKVDTSVHYNI 1065 ++ S E A+ + S +K KG E+ K D+S Sbjct: 721 SSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQ--- 777 Query: 1066 PELQSSSRAPPPQHNGQQEPPTARKGPPTQ 1095 S PP Q+P T ++ PP Q Sbjct: 778 ---PPKSAKPPAGGKSSQQPSTPQQAPPGQ 804 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 77.4 bits (189), Expect = 8e-14 Identities = 33/67 (49%), Positives = 57/67 (85%), Gaps = 1/67 (1%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQRE- 390 + D E RERE+ERE+E+ER +++R+KERE++REK++E+++EREREKE E++ ++++E Sbjct: 392 EKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEK 451 Query: 391 QRAREKE 397 ++ +EKE Sbjct: 452 EQDKEKE 458 Score = 76.3 bits (186), Expect = 2e-13 Identities = 37/82 (45%), Positives = 62/82 (75%), Gaps = 4/82 (4%) Query: 319 HSERMSGLSAERLQMDEELR---REREREREREREREADREREKEREREREKEREQEKER 375 HS + E+++ E ++ RE+ERERE+ERE+E +R + K+R++EREK+RE++KE+ Sbjct: 372 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 431 Query: 376 EREKERERELERQREQRAREKE 397 +RE+ERE+E E+ R+ + +EKE Sbjct: 432 DREREREKEHEKDRD-KEKEKE 452 Score = 73.2 bits (178), Expect = 1e-12 Identities = 27/63 (42%), Positives = 53/63 (84%) Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393 D + RE++RE+++E++RE +RE+E E++R++EKE+EQ+KE+EREK+R +E++ +R++ Sbjct: 416 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 475 Query: 394 REK 396 + + Sbjct: 476 KSR 478 Score = 70.1 bits (170), Expect = 1e-11 Identities = 45/137 (32%), Positives = 75/137 (54%), Gaps = 14/137 (10%) Query: 308 PELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKERERE--- 364 P S R S ++ + E +E+ER +E++RE+E +RE+E+E+E+E Sbjct: 354 PHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK 413 Query: 365 ---REKEREQEKEREREKERERELERQREQ-RAREKELLAAKALEPSFLPVAELHGLRGH 420 R+KERE+++E+++EK+RERE E++ E+ R +EKE K E E+ Sbjct: 414 NKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEI------ 467 Query: 421 ATEERGKPSEQLTPTRA 437 E+R K + TP R+ Sbjct: 468 -DEKRKKDKKSRTPPRS 483 Score = 58.9 bits (141), Expect = 3e-08 Identities = 31/80 (38%), Positives = 48/80 (60%), Gaps = 2/80 (2%) Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERERE 378 H+ S R +R + RER + R R R++ K+ RE+ KE+E+ KE++RE Sbjct: 338 HNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT-REKIKEKERVKEKDRE 396 Query: 379 KERERELERQRE-QRAREKE 397 KERERE ER++E +R + K+ Sbjct: 397 KEREREKEREKEKERGKNKD 416 Score = 57.0 bits (136), Expect = 1e-07 Identities = 30/89 (33%), Positives = 56/89 (62%), Gaps = 3/89 (3%) Query: 311 SHSSLAALHSERMSGLSAERLQM-DEELRREREREREREREREADREREKEREREREKER 369 SH+ + +R S + + E R+ R R R++ ++ RE+ KE+ER +EK+R Sbjct: 337 SHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT-REKIKEKERVKEKDR 395 Query: 370 EQEKEREREKERERELERQREQ-RAREKE 397 E+E+ERE+E+E+E+E + +++ + REK+ Sbjct: 396 EKEREREKEREKEKERGKNKDRDKEREKD 424 Score = 53.5 bits (127), Expect = 1e-06 Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 3/80 (3%) Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKERERERE-KEREQEKERER 377 H R S R Q D + ++R + RER R R R++ ++ +E+ +EKER + Sbjct: 333 HRSRSHNRSRSR-QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVK 391 Query: 378 EKERERELERQREQRAREKE 397 EK+RE+E ER++E R +EKE Sbjct: 392 EKDREKEREREKE-REKEKE 410 Score = 50.1 bits (118), Expect = 1e-05 Identities = 27/89 (30%), Positives = 39/89 (43%) Query: 308 PELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREK 367 PE S+ R S R RR+R + + R R R R+K+R R + Sbjct: 295 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 354 Query: 368 EREQEKEREREKERERELERQREQRAREK 396 +++ K RER K R R R + + REK Sbjct: 355 HKKRSKSRERRKSRSRSHSRDKRKDTREK 383 Score = 47.0 bits (110), Expect = 1e-04 Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 9/85 (10%) Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERE-- 376 HS R S R + R R R+++R R + ++R K RER + + R +++ Sbjct: 323 HSRRKRSQSKHRSRSHN---RSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKD 379 Query: 377 -REK--ERERELERQRE-QRAREKE 397 REK E+ER E+ RE +R REKE Sbjct: 380 TREKIKEKERVKEKDREKEREREKE 404 Score = 38.5 bits (88), Expect = 0.039 Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 20/84 (23%) Query: 334 DEELRREREREREREREREADREREKE--------------------REREREKEREQEK 373 ++E +++E+ERE++R +E D +R+K+ RER R + R + Sbjct: 448 EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSR 507 Query: 374 EREREKERERELERQREQRAREKE 397 K +R+ R R+R K+ Sbjct: 508 SPRTSKTIKRKSSRSPSPRSRNKK 531 Score = 37.7 bits (86), Expect = 0.067 Identities = 18/59 (30%), Positives = 27/59 (45%) Query: 339 REREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKE 397 R RER R R R + R + +R+ R +K+++RE ER RE+E Sbjct: 491 RSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERE 549 Score = 34.7 bits (78), Expect = 0.57 Identities = 17/63 (26%), Positives = 29/63 (46%) Query: 341 REREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKELLA 400 RER R R R K +R+ + +++K+RE+E + E+R RE+ Sbjct: 495 RERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSM 554 Query: 401 AKA 403 K+ Sbjct: 555 RKS 557 Score = 33.1 bits (74), Expect = 1.7 Identities = 23/101 (22%), Positives = 46/101 (45%), Gaps = 8/101 (7%) Query: 305 RYPPELSHSSLAALHSER-----MSGLSAERLQMDEELRREREREREREREREADREREK 359 R PP ++S + S R S S+ + + ++R+ R + D++REK Sbjct: 478 RTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK 537 Query: 360 EREREREKEREQEKEREREKERERELERQREQRA---REKE 397 ER+ E+ + R+ +R+ + + E+ + +EKE Sbjct: 538 ERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKE 578 Score = 32.3 bits (72), Expect = 2.8 Identities = 21/100 (21%), Positives = 43/100 (43%), Gaps = 1/100 (1%) Query: 314 SLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEK 373 S ++ S R S + R +++++RE+ER+ ER +ERER + Sbjct: 502 SRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER-RERERSTSMRKSSND 560 Query: 374 EREREKERERELERQREQRAREKELLAAKALEPSFLPVAE 413 +EK + + ++ +E + +K ++ P E Sbjct: 561 RDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 600 Score = 31.2 bits (69), Expect = 6.3 Identities = 19/79 (24%), Positives = 40/79 (50%), Gaps = 10/79 (12%) Query: 330 RLQMDEELRRERERE---REREREREA-------DREREKEREREREKEREQEKEREREK 379 R + ++ +RE+ER+ RERER DR+ +++ E+ +E+E +E + Sbjct: 526 RSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDS 585 Query: 380 ERERELERQREQRAREKEL 398 +E++ + R E ++ Sbjct: 586 SVSKEVDDKDAPRTEENKI 604 >gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo sapiens] Length = 508 Score = 77.4 bits (189), Expect = 8e-14 Identities = 33/67 (49%), Positives = 57/67 (85%), Gaps = 1/67 (1%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQRE- 390 + D E RERE+ERE+E+ER +++R+KERE++REK++E+++EREREKE E++ ++++E Sbjct: 276 EKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEK 335 Query: 391 QRAREKE 397 ++ +EKE Sbjct: 336 EQDKEKE 342 Score = 76.3 bits (186), Expect = 2e-13 Identities = 37/82 (45%), Positives = 62/82 (75%), Gaps = 4/82 (4%) Query: 319 HSERMSGLSAERLQMDEELR---REREREREREREREADREREKEREREREKEREQEKER 375 HS + E+++ E ++ RE+ERERE+ERE+E +R + K+R++EREK+RE++KE+ Sbjct: 256 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 315 Query: 376 EREKERERELERQREQRAREKE 397 +RE+ERE+E E+ R+ + +EKE Sbjct: 316 DREREREKEHEKDRD-KEKEKE 336 Score = 73.2 bits (178), Expect = 1e-12 Identities = 27/63 (42%), Positives = 53/63 (84%) Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393 D + RE++RE+++E++RE +RE+E E++R++EKE+EQ+KE+EREK+R +E++ +R++ Sbjct: 300 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 359 Query: 394 REK 396 + + Sbjct: 360 KSR 362 Score = 70.1 bits (170), Expect = 1e-11 Identities = 45/137 (32%), Positives = 75/137 (54%), Gaps = 14/137 (10%) Query: 308 PELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKERERE--- 364 P S R S ++ + E +E+ER +E++RE+E +RE+E+E+E+E Sbjct: 238 PHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK 297 Query: 365 ---REKEREQEKEREREKERERELERQREQ-RAREKELLAAKALEPSFLPVAELHGLRGH 420 R+KERE+++E+++EK+RERE E++ E+ R +EKE K E E+ Sbjct: 298 NKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEI------ 351 Query: 421 ATEERGKPSEQLTPTRA 437 E+R K + TP R+ Sbjct: 352 -DEKRKKDKKSRTPPRS 367 Score = 58.9 bits (141), Expect = 3e-08 Identities = 31/80 (38%), Positives = 48/80 (60%), Gaps = 2/80 (2%) Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERERE 378 H+ S R +R + RER + R R R++ K+ RE+ KE+E+ KE++RE Sbjct: 222 HNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT-REKIKEKERVKEKDRE 280 Query: 379 KERERELERQRE-QRAREKE 397 KERERE ER++E +R + K+ Sbjct: 281 KEREREKEREKEKERGKNKD 300 Score = 57.0 bits (136), Expect = 1e-07 Identities = 30/89 (33%), Positives = 56/89 (62%), Gaps = 3/89 (3%) Query: 311 SHSSLAALHSERMSGLSAERLQM-DEELRREREREREREREREADREREKEREREREKER 369 SH+ + +R S + + E R+ R R R++ ++ RE+ KE+ER +EK+R Sbjct: 221 SHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT-REKIKEKERVKEKDR 279 Query: 370 EQEKEREREKERERELERQREQ-RAREKE 397 E+E+ERE+E+E+E+E + +++ + REK+ Sbjct: 280 EKEREREKEREKEKERGKNKDRDKEREKD 308 Score = 53.5 bits (127), Expect = 1e-06 Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 3/80 (3%) Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKERERERE-KEREQEKERER 377 H R S R Q D + ++R + RER R R R++ ++ +E+ +EKER + Sbjct: 217 HRSRSHNRSRSR-QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVK 275 Query: 378 EKERERELERQREQRAREKE 397 EK+RE+E ER++E R +EKE Sbjct: 276 EKDREKEREREKE-REKEKE 294 Score = 50.1 bits (118), Expect = 1e-05 Identities = 27/89 (30%), Positives = 39/89 (43%) Query: 308 PELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREK 367 PE S+ R S R RR+R + + R R R R+K+R R + Sbjct: 179 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 238 Query: 368 EREQEKEREREKERERELERQREQRAREK 396 +++ K RER K R R R + + REK Sbjct: 239 HKKRSKSRERRKSRSRSHSRDKRKDTREK 267 Score = 47.0 bits (110), Expect = 1e-04 Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 9/85 (10%) Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERE-- 376 HS R S R + R R R+++R R + ++R K RER + + R +++ Sbjct: 207 HSRRKRSQSKHRSRSHN---RSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKD 263 Query: 377 -REK--ERERELERQRE-QRAREKE 397 REK E+ER E+ RE +R REKE Sbjct: 264 TREKIKEKERVKEKDREKEREREKE 288 Score = 38.5 bits (88), Expect = 0.039 Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 20/84 (23%) Query: 334 DEELRREREREREREREREADREREKE--------------------REREREKEREQEK 373 ++E +++E+ERE++R +E D +R+K+ RER R + R + Sbjct: 332 EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSR 391 Query: 374 EREREKERERELERQREQRAREKE 397 K +R+ R R+R K+ Sbjct: 392 SPRTSKTIKRKSSRSPSPRSRNKK 415 Score = 37.7 bits (86), Expect = 0.067 Identities = 18/59 (30%), Positives = 27/59 (45%) Query: 339 REREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKE 397 R RER R R R + R + +R+ R +K+++RE ER RE+E Sbjct: 375 RSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERE 433 Score = 34.7 bits (78), Expect = 0.57 Identities = 17/63 (26%), Positives = 29/63 (46%) Query: 341 REREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKELLA 400 RER R R R K +R+ + +++K+RE+E + E+R RE+ Sbjct: 379 RERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSM 438 Query: 401 AKA 403 K+ Sbjct: 439 RKS 441 Score = 33.1 bits (74), Expect = 1.7 Identities = 23/101 (22%), Positives = 46/101 (45%), Gaps = 8/101 (7%) Query: 305 RYPPELSHSSLAALHSER-----MSGLSAERLQMDEELRREREREREREREREADREREK 359 R PP ++S + S R S S+ + + ++R+ R + D++REK Sbjct: 362 RTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK 421 Query: 360 EREREREKEREQEKEREREKERERELERQREQRA---REKE 397 ER+ E+ + R+ +R+ + + E+ + +EKE Sbjct: 422 ERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKE 462 Score = 32.3 bits (72), Expect = 2.8 Identities = 21/100 (21%), Positives = 43/100 (43%), Gaps = 1/100 (1%) Query: 314 SLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEK 373 S ++ S R S + R +++++RE+ER+ ER +ERER + Sbjct: 386 SRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER-RERERSTSMRKSSND 444 Query: 374 EREREKERERELERQREQRAREKELLAAKALEPSFLPVAE 413 +EK + + ++ +E + +K ++ P E Sbjct: 445 RDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 484 Score = 31.2 bits (69), Expect = 6.3 Identities = 19/79 (24%), Positives = 40/79 (50%), Gaps = 10/79 (12%) Query: 330 RLQMDEELRRERERE---REREREREA-------DREREKEREREREKEREQEKEREREK 379 R + ++ +RE+ER+ RERER DR+ +++ E+ +E+E +E + Sbjct: 410 RSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDS 469 Query: 380 ERERELERQREQRAREKEL 398 +E++ + R E ++ Sbjct: 470 SVSKEVDDKDAPRTEENKI 488 >gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens] Length = 520 Score = 77.0 bits (188), Expect = 1e-13 Identities = 76/240 (31%), Positives = 114/240 (47%), Gaps = 45/240 (18%) Query: 252 PSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPP-LHPSAMHLHLSGV--RYPP 308 P++L P PF P + + L + P +P P PG+ PP L P+ H SG R Sbjct: 292 PTHLPPPPFLPPPPTVSTAPPL--IPPPGFP-PPPGAPPPSLIPTIESGHSSGYDSRSAR 348 Query: 309 ELSHSSLAALH----SERMSGLSAERLQMDEELRREREREREREREREADREREKERERE 364 + ++A H + L Q D RRE++R+RER+R+RE DR+R++ERER Sbjct: 349 AFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERT 408 Query: 365 REKEREQ-----------EKEREREKE------------RERELERQREQRAREKELLAA 401 RE+ERE+ ++ER R +E RE+E ER RE+R REKE Sbjct: 409 RERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKE-ERHRERRHREKEETRH 467 Query: 402 KALEPSFLPVAELHGLRGHATEE--RGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVP 459 K+ + + R H +EE + + R+++ K+AG + P P Q P Sbjct: 468 KS--------SRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSE-PAPEQESTEATP 518 >gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens] Length = 594 Score = 77.0 bits (188), Expect = 1e-13 Identities = 76/240 (31%), Positives = 114/240 (47%), Gaps = 45/240 (18%) Query: 252 PSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPP-LHPSAMHLHLSGV--RYPP 308 P++L P PF P + + L + P +P P PG+ PP L P+ H SG R Sbjct: 366 PTHLPPPPFLPPPPTVSTAPPL--IPPPGFP-PPPGAPPPSLIPTIESGHSSGYDSRSAR 422 Query: 309 ELSHSSLAALH----SERMSGLSAERLQMDEELRREREREREREREREADREREKERERE 364 + ++A H + L Q D RRE++R+RER+R+RE DR+R++ERER Sbjct: 423 AFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERT 482 Query: 365 REKEREQ-----------EKEREREKE------------RERELERQREQRAREKELLAA 401 RE+ERE+ ++ER R +E RE+E ER RE+R REKE Sbjct: 483 RERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKE-ERHRERRHREKEETRH 541 Query: 402 KALEPSFLPVAELHGLRGHATEE--RGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVP 459 K+ + + R H +EE + + R+++ K+AG + P P Q P Sbjct: 542 KS--------SRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSE-PAPEQESTEATP 592 >gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] Length = 290 Score = 76.6 bits (187), Expect = 1e-13 Identities = 41/73 (56%), Positives = 54/73 (73%), Gaps = 9/73 (12%) Query: 334 DEELRREREREREREREREADREREKEREREREKER--------EQEKEREREKEREREL 385 + E ++ RERER+R RERE DR+REKERER+ EK+R E+E++REREK++ERE Sbjct: 126 EREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERET 185 Query: 386 ERQRE-QRAREKE 397 ER R+ QR EKE Sbjct: 186 ERDRDRQRDTEKE 198 Score = 76.3 bits (186), Expect = 2e-13 Identities = 35/62 (56%), Positives = 52/62 (83%), Gaps = 1/62 (1%) Query: 336 ELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRARE 395 E+ R+RERE+++ RERE DR RE+ER+R+REKERE++ E++R+ +RE E ER+R+ R RE Sbjct: 120 EIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERD-RERE 178 Query: 396 KE 397 K+ Sbjct: 179 KQ 180 Score = 74.7 bits (182), Expect = 5e-13 Identities = 57/156 (36%), Positives = 78/156 (50%), Gaps = 40/156 (25%) Query: 282 PIPTPGSLPPLHPSAMHLHLS------GVRYPPELSHSSLAALHSERMSGLSA------- 328 P+ T L P A HLH S V P + S L + S R GL Sbjct: 15 PVKTSPLLVPSLTYAPHLHSSLGTLWVEVTIPLDFSRGRLGSQESPRSWGLGQAHKDADG 74 Query: 329 -----ERLQMDEELRRERERERERERER-------------------EADREREKE--RE 362 ER ++ E+ +ER+R+R+R+RER E DREREK+ RE Sbjct: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134 Query: 363 REREKEREQEKEREREKERERELERQRE-QRAREKE 397 RER++ RE+E++R+REKERER+ E+ R+ QR E E Sbjct: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETE 170 Score = 71.6 bits (174), Expect = 4e-12 Identities = 36/81 (44%), Positives = 58/81 (71%), Gaps = 4/81 (4%) Query: 321 ERMSGLSAERLQMDEELR---REREREREREREREADREREKEREREREKEREQEKERER 377 E+ G ER + E R RE+ERER+ E++R+ RE E ERER+RE+E+++E+E ER Sbjct: 128 EKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETER 187 Query: 378 EKERERELERQRE-QRAREKE 397 +++R+R+ E++RE Q RE++ Sbjct: 188 DRDRQRDTEKERERQTDRERD 208 Score = 71.2 bits (173), Expect = 5e-12 Identities = 37/69 (53%), Positives = 53/69 (76%), Gaps = 3/69 (4%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKER--EREKERERELERQR 389 Q + E RERE+++ RERER+ RERE++R+RE+E+ER+ EK+R +RE E ERE +R+R Sbjct: 118 QTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRER 177 Query: 390 E-QRAREKE 397 E Q+ RE E Sbjct: 178 EKQKERETE 186 Score = 71.2 bits (173), Expect = 5e-12 Identities = 29/58 (50%), Positives = 50/58 (86%) Query: 340 EREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKE 397 ER+RE +RE ERE DR RE++R+R+R KER++E++R+ E+++ER+ ER++E++ ++KE Sbjct: 216 ERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKE 273 Score = 69.7 bits (169), Expect = 2e-11 Identities = 30/75 (40%), Positives = 54/75 (72%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQ 391 + E RE ERE +R RER+ DR+R KER+RER+++ E++KER++E+++ER+ +++ E+ Sbjct: 216 ERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEK 275 Query: 392 RAREKELLAAKALEP 406 R +K+ + + P Sbjct: 276 RREDKKRKWGEGISP 290 Score = 69.3 bits (168), Expect = 2e-11 Identities = 31/63 (49%), Positives = 50/63 (79%), Gaps = 1/63 (1%) Query: 336 ELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQRE-QRAR 394 E ERER+RERE+++E + ER+++R+R+ EKERE++ +RER+++R+ + ERQRE R Sbjct: 166 ETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREG 225 Query: 395 EKE 397 E+E Sbjct: 226 ERE 228 Score = 67.4 bits (163), Expect = 8e-11 Identities = 34/80 (42%), Positives = 54/80 (67%), Gaps = 7/80 (8%) Query: 321 ERMSGLSAERLQMDEELRRERERERER------EREREADREREKEREREREKEREQEKE 374 ER G ER D E RER+ E++R E ERE DREREK++ERE E++R+++++ Sbjct: 136 ERDRGRERER-DRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRD 194 Query: 375 REREKERERELERQREQRAR 394 E+E+ER+ + ER R+++ + Sbjct: 195 TEKERERQTDRERDRQRKTQ 214 Score = 65.5 bits (158), Expect = 3e-10 Identities = 29/69 (42%), Positives = 51/69 (73%), Gaps = 3/69 (4%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQRE- 390 + + E R+R+R+ E+ERER+ DRER+++R+ + E++RE ++E ERE +R RE +R R+ Sbjct: 182 ERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDR 241 Query: 391 --QRAREKE 397 +R RE++ Sbjct: 242 GKERDRERD 250 Score = 65.1 bits (157), Expect = 4e-10 Identities = 27/66 (40%), Positives = 52/66 (78%), Gaps = 1/66 (1%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQ 391 + D E +++ERE ER+R+R+ D E+E+ER+ +RE++R+++ + ER++E +RE ER+ ++ Sbjct: 172 ERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDR 231 Query: 392 RAREKE 397 R RE++ Sbjct: 232 R-RERQ 236 Score = 64.7 bits (156), Expect = 5e-10 Identities = 28/67 (41%), Positives = 50/67 (74%), Gaps = 1/67 (1%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQ 391 Q + E R+R+R+R+ E+ERE +RE++R+R+ + ER++E +RE E+E +R ERQR++ Sbjct: 180 QKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR 239 Query: 392 -RAREKE 397 R +E++ Sbjct: 240 DRGKERD 246 Score = 63.9 bits (154), Expect = 9e-10 Identities = 27/67 (40%), Positives = 52/67 (77%), Gaps = 1/67 (1%) Query: 330 RLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERE-LERQ 388 + Q + + +RE ERE +R RE R+R++ +ER+RE++R++E+++ER+KER++E E++ Sbjct: 212 KTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKK 271 Query: 389 REQRARE 395 +E++ RE Sbjct: 272 KEEKRRE 278 Score = 62.4 bits (150), Expect = 3e-09 Identities = 30/72 (41%), Positives = 52/72 (72%), Gaps = 7/72 (9%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQ------EKEREREKEREREL 385 + + + RE+++ERE ER+R+ R+ EKERER+ ++ER++ E++RE ++E ERE Sbjct: 170 ERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERET 229 Query: 386 ERQRE-QRAREK 396 +R+RE QR R++ Sbjct: 230 DRRRERQRDRDR 241 Score = 50.8 bits (120), Expect = 8e-06 Identities = 21/52 (40%), Positives = 39/52 (75%) Query: 330 RLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKER 381 R + + R +ER+RER+R+ E +ER+KER++ER++++++EK RE +K + Sbjct: 232 RRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 75.5 bits (184), Expect = 3e-13 Identities = 152/643 (23%), Positives = 216/643 (33%), Gaps = 119/643 (18%) Query: 22 TTATVNPLTPS----PLNGALVPSGSPATSSALSAQAAPSSSFAAALRKLAKQAEEPRGS 77 T + P PS PL+G P + L P F L A Q + P G+ Sbjct: 276 TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFG--LPPQASQGQAPLGT 333 Query: 78 SLS------SESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPSTPPVVTIAPTKT 131 S + S P S A P P+ P+ P P P + PT Sbjct: 334 SPAAAYPHTSLQLPASQSALQSQQP---PREQPLPP---------APLAMPHIKPPPTTP 381 Query: 132 VNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQEKAGGPAIPSHLLST-PYPFGLSPSS- 189 + + ++ + S PP P K H S P P L P S Sbjct: 382 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 441 Query: 190 -----------VVQDSRFPPLNLQRP---VHHVVP-PSTVTEDYLRSFRPYHTTDDLRMS 234 + Q PP P +H V P P ++ P T + Sbjct: 442 PLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPST 501 Query: 235 SLPPLG-----LDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSL 289 S PP G P + AA S P P ++ + L P P P P S Sbjct: 502 STPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEE-ALDDAEEPESPPPPPRSP 560 Query: 290 PPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRRERERERERER 349 P P+ V P S S+ H +R A L + ++ E Sbjct: 561 SP-EPTV-------VDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEA 612 Query: 350 EREADREREKEREREREKEREQEKEREREKERERELER-------QREQRAREKELLAAK 402 +A RE E++ ERE+E+E+EKERERE+ERERE ER E R + +L Sbjct: 613 IEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPG 672 Query: 403 ALEPSFLP----VAELHGLRGHATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPV 458 + PSF P +A + G T SE P + +P HP + Sbjct: 673 HMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARP---------HVMSPTNRNHPFY-- 721 Query: 459 PTPHHTVPSLISNH--GIFSLPSSSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVS 516 P + L++ H G++++ + R+R LR +R+ + Sbjct: 722 -MPLNPTDPLLAYHMPGLYNVDPT------------------IRERELR----EREIRER 758 Query: 517 EFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQ 576 E R++ L + + G P E + P N P +HF L P P Sbjct: 759 EIRERELRERMKPGFEVKPPELD-----PLHPAAN--------PMEHFARHSALTIP-PT 804 Query: 577 LHAAPTALWNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAA 619 P A ++P N LE R P P R AA Sbjct: 805 AGPHPFASFHPGL---NPLERERLALAGPQLRPEMSYPDRLAA 844 Score = 43.5 bits (101), Expect = 0.001 Identities = 95/421 (22%), Positives = 134/421 (31%), Gaps = 85/421 (20%) Query: 447 APKPVQHPLHPV--PTPHHTVPSLISNHG----IFSLPSSSAATALLIQRTNEEEKWLAR 500 AP Q PLH P PH + H F LP ++ + T+ + Sbjct: 284 APSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG-TSPAAAYPHT 342 Query: 501 QRRLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDP 560 +L + QSQ Q EQ L PP P H T P P P Sbjct: 343 SLQLPASQSALQSQ-----QPPREQPL----PPAPLAMPHIKPPPTTPIPQLPAPQAHKH 393 Query: 561 PQHFGGPPPL-----ISPKPQL--------HAAPTALWNPVSLMDNTLETRRAESHSLHS 607 P H GP P + P P L H P+A P+ LM +S L S Sbjct: 394 PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--------PQSQPLPS 445 Query: 608 HPA---AFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPAPLDKYQPPPPPPREGGSLEH 664 PA S+ P + A + P + P PPP P S Sbjct: 446 SPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQH--PFVPGGPPPITPPTCPSTST 503 Query: 665 QPFLPGPG--PFLAELEKSTQTILGQQRASLPQAATFGE-LSGPLKPGSPYRPPVPRAPD 721 P PG P + S +I G LP E L +P SP PP PR+P Sbjct: 504 PPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESP--PPPPRSPS 561 Query: 722 PAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQ 781 P + + + +Q +Y LD Y+ + Sbjct: 562 P----------------EPTVVDTPSHASQSARFYKHLDRGYNSCARTD----------- 594 Query: 782 PPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPTIQSKRQTPSP 841 L F+ L G +++EE + + +R+ + RE + +R+ Sbjct: 595 -----------LYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERE 643 Query: 842 R 842 R Sbjct: 644 R 644 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 75.5 bits (184), Expect = 3e-13 Identities = 152/643 (23%), Positives = 216/643 (33%), Gaps = 119/643 (18%) Query: 22 TTATVNPLTPS----PLNGALVPSGSPATSSALSAQAAPSSSFAAALRKLAKQAEEPRGS 77 T + P PS PL+G P + L P F L A Q + P G+ Sbjct: 830 TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFG--LPPQASQGQAPLGT 887 Query: 78 SLS------SESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPSTPPVVTIAPTKT 131 S + S P S A P P+ P+ P P P + PT Sbjct: 888 SPAAAYPHTSLQLPASQSALQSQQP---PREQPLPP---------APLAMPHIKPPPTTP 935 Query: 132 VNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQEKAGGPAIPSHLLST-PYPFGLSPSS- 189 + + ++ + S PP P K H S P P L P S Sbjct: 936 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 995 Query: 190 -----------VVQDSRFPPLNLQRP---VHHVVP-PSTVTEDYLRSFRPYHTTDDLRMS 234 + Q PP P +H V P P ++ P T + Sbjct: 996 PLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPST 1055 Query: 235 SLPPLG-----LDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSL 289 S PP G P + AA S P P ++ + L P P P P S Sbjct: 1056 STPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEE-ALDDAEEPESPPPPPRSP 1114 Query: 290 PPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRRERERERERER 349 P P+ V P S S+ H +R A L + ++ E Sbjct: 1115 SP-EPTV-------VDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEA 1166 Query: 350 EREADREREKEREREREKEREQEKEREREKERERELER-------QREQRAREKELLAAK 402 +A RE E++ ERE+E+E+EKERERE+ERERE ER E R + +L Sbjct: 1167 IEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPG 1226 Query: 403 ALEPSFLP----VAELHGLRGHATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPV 458 + PSF P +A + G T SE P + +P HP + Sbjct: 1227 HMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARP---------HVMSPTNRNHPFY-- 1275 Query: 459 PTPHHTVPSLISNH--GIFSLPSSSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVS 516 P + L++ H G++++ + R+R LR +R+ + Sbjct: 1276 -MPLNPTDPLLAYHMPGLYNVDPT------------------IRERELR----EREIRER 1312 Query: 517 EFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQ 576 E R++ L + + G P E + P N P +HF L P P Sbjct: 1313 EIRERELRERMKPGFEVKPPELD-----PLHPAAN--------PMEHFARHSALTIP-PT 1358 Query: 577 LHAAPTALWNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAA 619 P A ++P N LE R P P R AA Sbjct: 1359 AGPHPFASFHPGL---NPLERERLALAGPQLRPEMSYPDRLAA 1398 Score = 43.5 bits (101), Expect = 0.001 Identities = 95/421 (22%), Positives = 134/421 (31%), Gaps = 85/421 (20%) Query: 447 APKPVQHPLHPV--PTPHHTVPSLISNHG----IFSLPSSSAATALLIQRTNEEEKWLAR 500 AP Q PLH P PH + H F LP ++ + T+ + Sbjct: 838 APSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG-TSPAAAYPHT 896 Query: 501 QRRLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDP 560 +L + QSQ Q EQ L PP P H T P P P Sbjct: 897 SLQLPASQSALQSQ-----QPPREQPL----PPAPLAMPHIKPPPTTPIPQLPAPQAHKH 947 Query: 561 PQHFGGPPPL-----ISPKPQL--------HAAPTALWNPVSLMDNTLETRRAESHSLHS 607 P H GP P + P P L H P+A P+ LM +S L S Sbjct: 948 PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--------PQSQPLPS 999 Query: 608 HPA---AFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPAPLDKYQPPPPPPREGGSLEH 664 PA S+ P + A + P + P PPP P S Sbjct: 1000 SPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQH--PFVPGGPPPITPPTCPSTST 1057 Query: 665 QPFLPGPG--PFLAELEKSTQTILGQQRASLPQAATFGE-LSGPLKPGSPYRPPVPRAPD 721 P PG P + S +I G LP E L +P SP PP PR+P Sbjct: 1058 PPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESP--PPPPRSPS 1115 Query: 722 PAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQ 781 P + + + +Q +Y LD Y+ + Sbjct: 1116 P----------------EPTVVDTPSHASQSARFYKHLDRGYNSCARTD----------- 1148 Query: 782 PPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPTIQSKRQTPSP 841 L F+ L G +++EE + + +R+ + RE + +R+ Sbjct: 1149 -----------LYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERE 1197 Query: 842 R 842 R Sbjct: 1198 R 1198 Score = 38.5 bits (88), Expect = 0.039 Identities = 15/37 (40%), Positives = 31/37 (83%), Gaps = 1/37 (2%) Query: 353 ADREREKEREREREKEREQEKEREREKERERELERQR 389 AD++++K++E++R+++R++E+E+ R+K RE E R R Sbjct: 3 ADKDKDKDKEKDRDRDRDREREK-RDKARESENSRPR 38 Score = 37.7 bits (86), Expect = 0.067 Identities = 14/36 (38%), Positives = 29/36 (80%), Gaps = 1/36 (2%) Query: 342 EREREREREREADREREKEREREREKEREQEKERER 377 ++++++++E++ DR+R++ERE+ R+K RE E R R Sbjct: 4 DKDKDKDKEKDRDRDRDREREK-RDKARESENSRPR 38 Score = 37.4 bits (85), Expect = 0.088 Identities = 14/37 (37%), Positives = 31/37 (83%), Gaps = 1/37 (2%) Query: 358 EKEREREREKEREQEKEREREK-ERERELERQREQRA 393 +K++++++EK+R+++++REREK ++ RE E R +R+ Sbjct: 4 DKDKDKDKEKDRDRDRDREREKRDKARESENSRPRRS 40 Score = 35.8 bits (81), Expect = 0.26 Identities = 13/36 (36%), Positives = 29/36 (80%), Gaps = 1/36 (2%) Query: 348 EREREADREREKEREREREKEREQEKEREREKERER 383 +++++ D+E++++R+R+RE+E+ ++K RE E R R Sbjct: 4 DKDKDKDKEKDRDRDRDREREK-RDKARESENSRPR 38 Score = 34.7 bits (78), Expect = 0.57 Identities = 10/30 (33%), Positives = 26/30 (86%) Query: 368 EREQEKEREREKERERELERQREQRAREKE 397 +++++K++E++++R+R+ ER++ +ARE E Sbjct: 4 DKDKDKDKEKDRDRDRDREREKRDKARESE 33 Score = 34.3 bits (77), Expect = 0.74 Identities = 18/78 (23%), Positives = 40/78 (51%), Gaps = 14/78 (17%) Query: 334 DEELRRERERERERERERE-ADREREKERERER-------------EKEREQEKEREREK 379 D++ +E++R+R+R+RERE D+ RE E R R E + ++++ + Sbjct: 6 DKDKDKEKDRDRDRDREREKRDKARESENSRPRRSCTLEGGAKNYAESDHSEDEDNDNNS 65 Query: 380 ERERELERQREQRAREKE 397 E ++ +++ +K+ Sbjct: 66 ATAEESTKKNKKKPPKKK 83 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 75.5 bits (184), Expect = 3e-13 Identities = 152/643 (23%), Positives = 216/643 (33%), Gaps = 119/643 (18%) Query: 22 TTATVNPLTPS----PLNGALVPSGSPATSSALSAQAAPSSSFAAALRKLAKQAEEPRGS 77 T + P PS PL+G P + L P F L A Q + P G+ Sbjct: 830 TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFG--LPPQASQGQAPLGT 887 Query: 78 SLS------SESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPSTPPVVTIAPTKT 131 S + S P S A P P+ P+ P P P + PT Sbjct: 888 SPAAAYPHTSLQLPASQSALQSQQP---PREQPLPP---------APLAMPHIKPPPTTP 935 Query: 132 VNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQEKAGGPAIPSHLLST-PYPFGLSPSS- 189 + + ++ + S PP P K H S P P L P S Sbjct: 936 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 995 Query: 190 -----------VVQDSRFPPLNLQRP---VHHVVP-PSTVTEDYLRSFRPYHTTDDLRMS 234 + Q PP P +H V P P ++ P T + Sbjct: 996 PLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPST 1055 Query: 235 SLPPLG-----LDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSL 289 S PP G P + AA S P P ++ + L P P P P S Sbjct: 1056 STPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEE-ALDDAEEPESPPPPPRSP 1114 Query: 290 PPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRRERERERERER 349 P P+ V P S S+ H +R A L + ++ E Sbjct: 1115 SP-EPTV-------VDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEA 1166 Query: 350 EREADREREKEREREREKEREQEKEREREKERERELER-------QREQRAREKELLAAK 402 +A RE E++ ERE+E+E+EKERERE+ERERE ER E R + +L Sbjct: 1167 IEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPG 1226 Query: 403 ALEPSFLP----VAELHGLRGHATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPV 458 + PSF P +A + G T SE P + +P HP + Sbjct: 1227 HMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARP---------HVMSPTNRNHPFY-- 1275 Query: 459 PTPHHTVPSLISNH--GIFSLPSSSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVS 516 P + L++ H G++++ + R+R LR +R+ + Sbjct: 1276 -MPLNPTDPLLAYHMPGLYNVDPT------------------IRERELR----EREIRER 1312 Query: 517 EFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQ 576 E R++ L + + G P E + P N P +HF L P P Sbjct: 1313 EIRERELRERMKPGFEVKPPELD-----PLHPAAN--------PMEHFARHSALTIP-PT 1358 Query: 577 LHAAPTALWNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAA 619 P A ++P N LE R P P R AA Sbjct: 1359 AGPHPFASFHPGL---NPLERERLALAGPQLRPEMSYPDRLAA 1398 Score = 43.5 bits (101), Expect = 0.001 Identities = 95/421 (22%), Positives = 134/421 (31%), Gaps = 85/421 (20%) Query: 447 APKPVQHPLHPV--PTPHHTVPSLISNHG----IFSLPSSSAATALLIQRTNEEEKWLAR 500 AP Q PLH P PH + H F LP ++ + T+ + Sbjct: 838 APSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG-TSPAAAYPHT 896 Query: 501 QRRLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDP 560 +L + QSQ Q EQ L PP P H T P P P Sbjct: 897 SLQLPASQSALQSQ-----QPPREQPL----PPAPLAMPHIKPPPTTPIPQLPAPQAHKH 947 Query: 561 PQHFGGPPPL-----ISPKPQL--------HAAPTALWNPVSLMDNTLETRRAESHSLHS 607 P H GP P + P P L H P+A P+ LM +S L S Sbjct: 948 PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--------PQSQPLPS 999 Query: 608 HPA---AFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPAPLDKYQPPPPPPREGGSLEH 664 PA S+ P + A + P + P PPP P S Sbjct: 1000 SPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQH--PFVPGGPPPITPPTCPSTST 1057 Query: 665 QPFLPGPG--PFLAELEKSTQTILGQQRASLPQAATFGE-LSGPLKPGSPYRPPVPRAPD 721 P PG P + S +I G LP E L +P SP PP PR+P Sbjct: 1058 PPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESP--PPPPRSPS 1115 Query: 722 PAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQ 781 P + + + +Q +Y LD Y+ + Sbjct: 1116 P----------------EPTVVDTPSHASQSARFYKHLDRGYNSCARTD----------- 1148 Query: 782 PPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPTIQSKRQTPSP 841 L F+ L G +++EE + + +R+ + RE + +R+ Sbjct: 1149 -----------LYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERE 1197 Query: 842 R 842 R Sbjct: 1198 R 1198 Score = 38.5 bits (88), Expect = 0.039 Identities = 15/37 (40%), Positives = 31/37 (83%), Gaps = 1/37 (2%) Query: 353 ADREREKEREREREKEREQEKEREREKERERELERQR 389 AD++++K++E++R+++R++E+E+ R+K RE E R R Sbjct: 3 ADKDKDKDKEKDRDRDRDREREK-RDKARESENSRPR 38 Score = 37.7 bits (86), Expect = 0.067 Identities = 14/36 (38%), Positives = 29/36 (80%), Gaps = 1/36 (2%) Query: 342 EREREREREREADREREKEREREREKEREQEKERER 377 ++++++++E++ DR+R++ERE+ R+K RE E R R Sbjct: 4 DKDKDKDKEKDRDRDRDREREK-RDKARESENSRPR 38 Score = 37.4 bits (85), Expect = 0.088 Identities = 14/37 (37%), Positives = 31/37 (83%), Gaps = 1/37 (2%) Query: 358 EKEREREREKEREQEKEREREK-ERERELERQREQRA 393 +K++++++EK+R+++++REREK ++ RE E R +R+ Sbjct: 4 DKDKDKDKEKDRDRDRDREREKRDKARESENSRPRRS 40 Score = 35.8 bits (81), Expect = 0.26 Identities = 13/36 (36%), Positives = 29/36 (80%), Gaps = 1/36 (2%) Query: 348 EREREADREREKEREREREKEREQEKEREREKERER 383 +++++ D+E++++R+R+RE+E+ ++K RE E R R Sbjct: 4 DKDKDKDKEKDRDRDRDREREK-RDKARESENSRPR 38 Score = 34.7 bits (78), Expect = 0.57 Identities = 10/30 (33%), Positives = 26/30 (86%) Query: 368 EREQEKEREREKERERELERQREQRAREKE 397 +++++K++E++++R+R+ ER++ +ARE E Sbjct: 4 DKDKDKDKEKDRDRDRDREREKRDKARESE 33 Score = 34.3 bits (77), Expect = 0.74 Identities = 18/78 (23%), Positives = 40/78 (51%), Gaps = 14/78 (17%) Query: 334 DEELRRERERERERERERE-ADREREKERERER-------------EKEREQEKEREREK 379 D++ +E++R+R+R+RERE D+ RE E R R E + ++++ + Sbjct: 6 DKDKDKEKDRDRDRDREREKRDKARESENSRPRRSCTLEGGAKNYAESDHSEDEDNDNNS 65 Query: 380 ERERELERQREQRAREKE 397 E ++ +++ +K+ Sbjct: 66 ATAEESTKKNKKKPPKKK 83 >gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial [Homo sapiens] Length = 213 Score = 74.3 bits (181), Expect = 6e-13 Identities = 41/82 (50%), Positives = 57/82 (69%), Gaps = 15/82 (18%) Query: 332 QMDEELRRERERERERE----------REREADREREKEREREREKERE----QEKERER 377 Q D E RER+R+RERE RERE DR+R++E ERER+KERE E +RER Sbjct: 49 QRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRER 108 Query: 378 EKERERELERQRE-QRAREKEL 398 +K++ERE+ER R+ +R ++KE+ Sbjct: 109 QKQKEREMERVRDREREKQKEM 130 Score = 73.2 bits (178), Expect = 1e-12 Identities = 44/126 (34%), Positives = 72/126 (57%), Gaps = 14/126 (11%) Query: 321 ERMSGLSAERLQMDEELR-REREREREREREREADREREKEREREREKEREQEKEREREK 379 E+ + ER + E R R+RE ERER++ERE DR E +RER+++KERE E+ R+RE+ Sbjct: 65 EKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRER 124 Query: 380 ERERELERQRE---QRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTR 436 E+++E+ R+R+ + RE+E A + E R TE+R + E+ Sbjct: 125 EKQKEMGRERQTDRETDRERERQAERERETG----------RERKTEDRHRERERERKRE 174 Query: 437 AEKLKD 442 E+ ++ Sbjct: 175 RERKRE 180 Score = 72.8 bits (177), Expect = 2e-12 Identities = 32/71 (45%), Positives = 52/71 (73%) Query: 320 SERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREK 379 ++R + E D R+R+R+RER RER+ DREREK+ +RE E++RE+E++R+R++ Sbjct: 27 TDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQR 86 Query: 380 ERERELERQRE 390 E ERE +++RE Sbjct: 87 ETERERDKERE 97 Score = 72.4 bits (176), Expect = 2e-12 Identities = 33/67 (49%), Positives = 51/67 (76%), Gaps = 1/67 (1%) Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQRE- 390 + D + RER RER+R+RERE +RE ER+RERE++R++++E ERE+++ERE +R E Sbjct: 45 ERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTET 104 Query: 391 QRAREKE 397 R R+K+ Sbjct: 105 DRERQKQ 111 Score = 71.2 bits (173), Expect = 5e-12 Identities = 34/77 (44%), Positives = 55/77 (71%), Gaps = 1/77 (1%) Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380 ER ER + E +R ER+R+R+RE +RER+++RERE++ +RE E++RERE++ Sbjct: 22 ERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERD 81 Query: 381 RERELERQREQRAREKE 397 R+R+ E +RE R +E+E Sbjct: 82 RDRQRETERE-RDKERE 97 Score = 71.2 bits (173), Expect = 5e-12 Identities = 45/88 (51%), Positives = 60/88 (68%), Gaps = 12/88 (13%) Query: 321 ERMSGLSAERLQMDEELRRERERERERERE-----READREREKEREREREKEREQE-KE 374 E+ + ER Q D E RERER+ ERERE + DR RE+ERER+RE+ER++E KE Sbjct: 125 EKQKEMGRER-QTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKE 183 Query: 375 RER----EKERERELERQRE-QRAREKE 397 RER E+ER+RE +R+R+ QR E+E Sbjct: 184 RERHTDMERERQRETDRKRDRQRESERE 211 Score = 69.7 bits (169), Expect = 2e-11 Identities = 38/85 (44%), Positives = 57/85 (67%), Gaps = 7/85 (8%) Query: 321 ERMSGLSAERLQMDEELRRERERERE----REREREADREREKEREREREKEREQEKERE 376 +R E + + +R+RER RE RERE++ DRE E++RERER+++R++E ERE Sbjct: 32 DRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERE 91 Query: 377 REKERE--RELERQRE-QRAREKEL 398 R+KERE R E RE Q+ +E+E+ Sbjct: 92 RDKERETDRHTETDRERQKQKEREM 116 Score = 68.9 bits (167), Expect = 3e-11 Identities = 35/73 (47%), Positives = 52/73 (71%), Gaps = 7/73 (9%) Query: 332 QMDEELRRERERERERE----REREADREREKEREREREKEREQEKER---EREKERERE 384 Q + E+ R R+RERE++ RER+ DRE ++ERER+ E+ERE +ER +R +ERERE Sbjct: 111 QKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERE 170 Query: 385 LERQREQRAREKE 397 +R+RE++ KE Sbjct: 171 RKRERERKRETKE 183 Score = 67.8 bits (164), Expect = 6e-11 Identities = 36/89 (40%), Positives = 56/89 (62%), Gaps = 14/89 (15%) Query: 322 RMSGLSAERLQMDEELRRERERER-------------EREREREADREREKEREREREKE 368 R + E + E RRE +RER ER+R+R+ +R RE++R+REREK+ Sbjct: 8 RHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQ 67 Query: 369 REQEKEREREKERERELERQREQRAREKE 397 ++E ER+RE+ER+R+ +R+ E R R+KE Sbjct: 68 TDREGERQRERERDRDRQRETE-RERDKE 95 Score = 67.0 bits (162), Expect = 1e-10 Identities = 32/70 (45%), Positives = 50/70 (71%), Gaps = 5/70 (7%) Query: 334 DEELRREREREREREREREADREREKEREREREKEREQE-----KEREREKERERELERQ 388 D E +++E RER+ +RE DRERE++ ERERE RE++ +ERERE++RERE +R+ Sbjct: 121 DREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRE 180 Query: 389 REQRAREKEL 398 ++R R ++ Sbjct: 181 TKERERHTDM 190 Score = 65.9 bits (159), Expect = 2e-10 Identities = 34/71 (47%), Positives = 49/71 (69%), Gaps = 1/71 (1%) Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADRERE-KEREREREKEREQEKEREREK 379 ER ER E +R RERERER+RE +R+RE KERER + ERE+++E +R++ Sbjct: 143 ERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKR 202 Query: 380 ERERELERQRE 390 +R+RE ER+R+ Sbjct: 203 DRQRESERERD 213 Score = 64.3 bits (155), Expect = 7e-10 Identities = 32/66 (48%), Positives = 46/66 (69%), Gaps = 1/66 (1%) Query: 320 SERMSGLSAERLQMDEELRREREREREREREREA-DREREKEREREREKEREQEKERERE 378 +ER ER D RERER+RERER+RE +RER + ERER++E +++++R+RE Sbjct: 148 AERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRE 207 Query: 379 KERERE 384 ERER+ Sbjct: 208 SERERD 213 Score = 50.1 bits (118), Expect = 1e-05 Identities = 27/79 (34%), Positives = 46/79 (58%), Gaps = 12/79 (15%) Query: 331 LQMDEELRREREREREREREREADREREKERER-----------EREKEREQEKEREREK 379 ++ E R +R+RE RE ++ER+R ER+++R++E+ RER++ Sbjct: 1 MESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDR 60 Query: 380 ERERELERQRE-QRAREKE 397 +RERE + RE +R RE+E Sbjct: 61 DREREKQTDREGERQRERE 79 Score = 48.5 bits (114), Expect = 4e-05 Identities = 23/50 (46%), Positives = 32/50 (64%) Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKE 368 H ER ER + E RER + ERER+RE DR+R+++RE ERE++ Sbjct: 164 HRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213 Score = 34.7 bits (78), Expect = 0.57 Identities = 30/116 (25%), Positives = 53/116 (45%), Gaps = 16/116 (13%) Query: 1082 QQEPPTARKGPPTQELDRDSE---------EEEEEDDEDGEDEEEVPKRKWQGIEAVFEA 1132 ++E T R+G +E +RD + ++E E D E + E K+K + +E V + Sbjct: 63 EREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDR 122 Query: 1133 YQEHIEEQNLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERER 1188 +E +E ERQ + R E + AE+ + E +++ + ERER Sbjct: 123 EREKQKEMGRERQTDRETDRERERQ-------AERERETGRERKTEDRHRERERER 171 Score = 34.3 bits (77), Expect = 0.74 Identities = 30/120 (25%), Positives = 52/120 (43%), Gaps = 2/120 (1%) Query: 1078 QHNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHI 1137 Q ++E R+ E DR+ ++++E + E D E K+K G E + + Sbjct: 85 QRETERERDKERETDRHTETDRERQKQKEREMERVRDRER-EKQKEMGRERQTDRETDRE 143 Query: 1138 EEQNLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERERLQAELDHLR 1197 E+ ER+ + R+ E RH ++ E + +++ ERER Q E D R Sbjct: 144 RERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERER-QRETDRKR 202 >gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens] Length = 588 Score = 74.3 bits (181), Expect = 6e-13 Identities = 77/248 (31%), Positives = 114/248 (45%), Gaps = 52/248 (20%) Query: 252 PSYLAPHPFPHPAFRMDDSYCLSALRSPFYPI--------PTPGSLPP-LHPSAMHLHLS 302 P++L P PF P + + L + P PI P PG+ PP L P+ H S Sbjct: 351 PTHLPPPPFLPPPPTVSTAPPL--IPPPGIPITVPPPGFPPPPGAPPPSLIPTIESGHSS 408 Query: 303 GV--RYPPELSHSSLAALH----SERMSGLSAERLQMDEELRREREREREREREREADRE 356 G R + ++A H + L Q D RRE++R+RER+R+RE DR+ Sbjct: 409 GYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRD 468 Query: 357 REKEREREREKEREQ-----------EKEREREKE------------RERELERQREQRA 393 R++ERER RE+ERE+ ++ER R +E RE+E ER RE+R Sbjct: 469 RDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKE-ERHRERRH 527 Query: 394 REKELLAAKALEPSFLPVAELHGLRGHATEE--RGKPSEQLTPTRAEKLKDAGLQAPKPV 451 REKE K+ + + R H +EE + + R+++ K+AG + P P Sbjct: 528 REKEETRHKS--------SRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSE-PAPE 578 Query: 452 QHPLHPVP 459 Q P Sbjct: 579 QESTEATP 586 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 73.9 bits (180), Expect = 8e-13 Identities = 138/555 (24%), Positives = 187/555 (33%), Gaps = 108/555 (19%) Query: 49 ALSAQAAPSSSFAAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPI 108 A S + P + A L ++ + SS SE+ V+ A H P PMGP Sbjct: 589 APSPRCPPPLACALQAFSLGQREDSLEVSSFCSEAL-VTCAALTHPR---VPPLQPMGPT 644 Query: 109 ------IVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPL 162 + PP S PP P +V + + AG S+G P+ Sbjct: 645 CPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAG---------PV 695 Query: 163 PQEKAGGPAIPSHLLSTPYPFGLSPSSVVQDSRFPPLNLQRPVHHVV------------- 209 P + G P +HL GLS +V PP L P +H Sbjct: 696 PSARPGPPTTANHL-------GLSVPGLVS---VPPRLLPGPENHRAGSNEDPILAPSGT 745 Query: 210 PPSTVTEDYL---RSFRPYHTTDDLRMSS--------------------LPPLGLDPATA 246 PP T+ D R RP D +S LPPL P + Sbjct: 746 PPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSG 805 Query: 247 AAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYP-------IPTPGSLPPLHPSAMHL 299 A + P P ++ L A P P +P P +LPP P + Sbjct: 806 ATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPP--PQLVPE 863 Query: 300 HLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREK 359 G PP L L ++ S E + +EE E E E E E + E + E E+ Sbjct: 864 GTPGGGGPPALEED-LTVININS----SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEE 918 Query: 360 EREREREKEREQEKEREREKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRG 419 E E E+E E+ +E E+E E E E + E E+EL + LE G G Sbjct: 919 EYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLE---------FGTAG 969 Query: 420 HATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHP-LHPVPTPHHTV------PSLISNH 472 EE P L P P P P + P P P + P Sbjct: 970 GEVEEGAPPPPTLPPA-----------LPPPESPPKVQPEPEPEPGLLLEVEEPGTEEER 1018 Query: 473 GIFSLPSSSAATALLIQRTNEEEKWLARQRRLRQE-KEDRQSQVSEFRQQVLEQHLDMGR 531 G + P + A AL Q E E QE E+ S ++ E D + Sbjct: 1019 GADTAP-TLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQ 1077 Query: 532 PPVPAEAEHRPESTT 546 PP AE E+ T Sbjct: 1078 PPPETPAEEEMETET 1092 Score = 42.4 bits (98), Expect = 0.003 Identities = 30/86 (34%), Positives = 40/86 (46%), Gaps = 10/86 (11%) Query: 1066 PELQSSSRAPPPQHNGQQEPPTARKGPPTQELD--------RDSEEEEEEDDEDGEDEEE 1117 P + PPPQ + P GPP E D D EEEEEE++E+ E+EEE Sbjct: 847 PPVPGPVTLPPPQLVPEGTPGGG--GPPALEEDLTVININSSDEEEEEEEEEEEEEEEEE 904 Query: 1118 VPKRKWQGIEAVFEAYQEHIEEQNLE 1143 + ++ E E Y E EE+ E Sbjct: 905 EEEEDFEEEEEDEEEYFEEEEEEEEE 930 Score = 39.7 bits (91), Expect = 0.018 Identities = 19/49 (38%), Positives = 31/49 (63%) Query: 1095 QELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQNLE 1143 +E + + EEEEEE++ED E+EEE + ++ E E ++E EE+ E Sbjct: 893 EEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGE 941 Score = 34.3 bits (77), Expect = 0.74 Identities = 69/328 (21%), Positives = 118/328 (35%), Gaps = 49/328 (14%) Query: 651 PPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSGPLKPGS 710 P PPPP G + P + GP A S ++ LP A GPL P Sbjct: 797 PLPPPPPSGAT---PPPIAPTGPPTA----SPPVPAKEEPEELPAAP------GPLPPPP 843 Query: 711 PYRPPVP---RAPDPAYIYD--------EFLQQRRRLV---SKLDLEERRRREAQEKGYY 756 P PPVP P P + + L++ ++ S + EE E +E+ Sbjct: 844 PPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEE 903 Query: 757 YDLDDSYDESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRR 816 + ++ ++E +E+E E+ + + E+ E + ++++EEL + Sbjct: 904 EEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDL 963 Query: 817 K---RRRMLRERSPSPPTIQSKRQTPSPRLALSTRYSPDE----MNNSPNFEEKKKFLTI 869 + + E +P PPT+ P + P+ P EE++ T Sbjct: 964 EFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTA 1023 Query: 870 FNLTHISAEKRKDKER-------------LVEMLRAMKQKALSAAVAD--SLTNSPRDSP 914 L + + + ER LVE + L D P ++P Sbjct: 1024 PTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETP 1083 Query: 915 AVSLSEPATQQASLDVEKPVGVAASLSD 942 A E T+ +L ++ AA L+D Sbjct: 1084 AEEEMETETEAEALQEKEQDDTAAMLAD 1111 Score = 33.9 bits (76), Expect = 0.97 Identities = 57/231 (24%), Positives = 80/231 (34%), Gaps = 25/231 (10%) Query: 507 EKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTT-RPGPNRHEPGG-RDPPQHF 564 ++ED +VS F + L + P VP P T P P P R PP H Sbjct: 609 QRED-SLEVSSFCSEALVTCAALTHPRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHP 667 Query: 565 GGPPPLISPKPQLHAAPTALWNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAAVPLVK 624 GP P + P P+A P + + + R + +H P LV Sbjct: 668 PGPMPSVGSMPSAGPMPSAGPMPSA---GPVPSARPGPPTTANHLGLSVPG------LVS 718 Query: 625 VERVFCPEKAEEGPRKREPAPLDKYQPPPP--PPRE--GGSLEHQPFLPGPGPFLAELEK 680 V P E L PPP PP E GG + F+ +++E Sbjct: 719 VPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEI 778 Query: 681 STQT-------ILGQQRASLPQAATFGELSGPLKPGSP--YRPPVPRAPDP 722 S ++ I+ + LP G P+ P P PPVP +P Sbjct: 779 SLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEP 829 Score = 32.7 bits (73), Expect = 2.2 Identities = 15/33 (45%), Positives = 18/33 (54%) Query: 1075 PPPQHNGQQEPPTARKGPPTQELDRDSEEEEEE 1107 PPP +G PP A GPPT ++EE EE Sbjct: 799 PPPPPSGATPPPIAPTGPPTASPPVPAKEEPEE 831 Score = 32.3 bits (72), Expect = 2.8 Identities = 54/247 (21%), Positives = 80/247 (32%), Gaps = 68/247 (27%) Query: 494 EEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRH 553 EE++ + L +E+E+ + E ++V + L+ G E P T P Sbjct: 932 EEEFEEEEGELEEEEEEEDEEEEEELEEV--EDLEFGTAGGEVEEGAPPPPTLPPA---- 985 Query: 554 EPGGRDPPQHFGGPPPLISPKPQ-------------------LHAAPTALWNPVSLMDNT 594 PP+ PP + P+P+ APT P +L Sbjct: 986 ----LPPPES----PPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLA--PEALPSQG 1035 Query: 595 LETRRAESHSLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPAPLDKYQPPPP 654 R ES PAA P ++ E+ E+G DK QPPP Sbjct: 1036 EVEREGES------PAAGPPPQELVEEEPSAPPTLLEEETEDGS--------DKVQPPPE 1081 Query: 655 PPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSGPLKPGSPYRP 714 P E E+E T+ Q++ AA + P +P Sbjct: 1082 TPAE-----------------EEMETETEAEALQEKEQDDTAAMLADFID--CPPDDEKP 1122 Query: 715 PVPRAPD 721 P P PD Sbjct: 1123 PPPTEPD 1129 Score = 30.8 bits (68), Expect = 8.2 Identities = 23/70 (32%), Positives = 30/70 (42%), Gaps = 8/70 (11%) Query: 1074 APPPQHNGQQEPPTARKGPPTQELDRDSEEEE----EEDDEDGEDE----EEVPKRKWQG 1125 A P Q ++E + GPP QEL + EE+ EDG D+ E P + Sbjct: 1030 ALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEME 1089 Query: 1126 IEAVFEAYQE 1135 E EA QE Sbjct: 1090 TETEAEALQE 1099 >gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens] Length = 1341 Score = 72.8 bits (177), Expect = 2e-12 Identities = 36/88 (40%), Positives = 59/88 (67%), Gaps = 5/88 (5%) Query: 310 LSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKER 369 L+ S + +ER AER + E+ R+E+E E ++ERE+EA+RER ++ ERE+ +E Sbjct: 1229 LTDSQIVQKEAER-----AERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREH 1283 Query: 370 EQEKEREREKERERELERQREQRAREKE 397 +E++RERE+ERER+ + R R++E Sbjct: 1284 SRERDRERERERERDRGDRDRDRERDRE 1311 Score = 72.4 bits (176), Expect = 2e-12 Identities = 37/103 (35%), Positives = 62/103 (60%), Gaps = 1/103 (0%) Query: 317 ALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERE 376 A +ER R + +EE ++ERE+E ERER R+ +RE+ +E RER++ERE+E+ER+ Sbjct: 1239 AERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERD 1298 Query: 377 R-EKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLR 418 R +++R+RE +R+R + ++ PV + G R Sbjct: 1299 RGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341 Score = 52.4 bits (124), Expect = 3e-06 Identities = 31/79 (39%), Positives = 48/79 (60%), Gaps = 3/79 (3%) Query: 339 RERERERERE-REREADREREKEREREREKEREQEKERERE--KERERELERQREQRARE 395 R +RE+ER RE+ A+RERE ER ERE ++++ RE + R R +R+R++RA+ Sbjct: 1132 RAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKS 1191 Query: 396 KELLAAKALEPSFLPVAEL 414 KE + K + P A+L Sbjct: 1192 KEKKSEKKEKAQEEPPAKL 1210 Score = 48.9 bits (115), Expect = 3e-05 Identities = 38/135 (28%), Positives = 53/135 (39%), Gaps = 40/135 (29%) Query: 279 PFYPIPTPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELR 338 P +P P P PP HP R + E+ R Sbjct: 1116 PLHPPPPPPVQPPQHP-----------------------------------RAEQREQER 1140 Query: 339 REREREREREREREADREREKEREREREKEREQEKER-----EREKERERELERQREQRA 393 RE+ ERERE E ERE +R+K RE + R R KER + E++ E++ Sbjct: 1141 AVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKE 1200 Query: 394 REKELLAAKALEPSF 408 + +E AK L+ F Sbjct: 1201 KAQEEPPAKLLDDLF 1215 Score = 43.9 bits (102), Expect = 0.001 Identities = 55/202 (27%), Positives = 74/202 (36%), Gaps = 53/202 (26%) Query: 328 AERLQMDEELRREREREREREREREADREREKERER-----------------------E 364 A+R EE E E E E + E E D E +K RE E Sbjct: 263 ADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDE 322 Query: 365 REKEREQEKE---------REREKERERELERQREQRAREKELLAAKALEPSFLPVAELH 415 R K R QE+E R +E+ R+ L RQ++ EKE+ LE + Sbjct: 323 RPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQ----EKEMKTTSPLEEEEREIKSSQ 378 Query: 416 GLRGHA--------TEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVPTPHHTVPS 467 GL+ + TE+R K S P + + + P P+ P PH P Sbjct: 379 GLKEKSKSPSPPRLTEDRKKASLVALPEQTASEE----ETPPPLLTKEASSPPPH---PQ 431 Query: 468 LISNHGIFSLPSSSAATALLIQ 489 L S I P A +LIQ Sbjct: 432 LHSEEEI--EPMEGPAPPVLIQ 451 Score = 39.7 bits (91), Expect = 0.018 Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 24/145 (16%) Query: 308 PELSHSSLAALHSERMSG-LSAERLQMDEELRREREREREREREREADR--------ERE 358 PEL S HS R S +S E+ D+E R+ ER R R+ A + E E Sbjct: 194 PELELSR----HSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEE 249 Query: 359 KERE-----------REREKEREQEKEREREKERERELERQREQRAREKELLAAKALEPS 407 +++E R + E E+E+E E E++ E E Q++RE +L E Sbjct: 250 EDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGE 309 Query: 408 FLPVAELHGLRGHATEERGKPSEQL 432 +P + + + R + E L Sbjct: 310 EIPRVKPEEMMDERPKTRSQEQEVL 334 Score = 35.4 bits (80), Expect = 0.33 Identities = 31/135 (22%), Positives = 59/135 (43%), Gaps = 11/135 (8%) Query: 1070 SSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEA- 1128 S P + Q+ P + + L + EEEEEE++E+ ++EEE + EA Sbjct: 240 SEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAP 299 Query: 1129 VFEAYQEH--------IEEQNLERQVLQTQCRRLEAR--HYSLSLTAEQLSHSVAELRSQ 1178 + + ++E EE ER ++Q + + R ++ S + SH + + + Sbjct: 300 ILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEK 359 Query: 1179 KQKMVSERERLQAEL 1193 + K S E + E+ Sbjct: 360 EMKTTSPLEEEEREI 374 Score = 33.5 bits (75), Expect = 1.3 Identities = 48/217 (22%), Positives = 80/217 (36%), Gaps = 29/217 (13%) Query: 327 SAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELE 386 S E + R+++E+E + E + K + +EK + R E ++ L Sbjct: 343 SQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLV 402 Query: 387 RQREQRAREKE----LLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKD 442 EQ A E+E LL +A P P +LH +EE +P E P Sbjct: 403 ALPEQTASEEETPPPLLTKEASSPP--PHPQLH------SEEEIEPMEGPAP-------- 446 Query: 443 AGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQR 502 PV L P T T L+S H + + S ++ + + + + Sbjct: 447 -------PVLIQLSPPNTDADTRELLVSQHTVQLVGGLSPLSSPSDTKAESPAEKVPEES 499 Query: 503 RLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAE 539 L ++ + S Q+ LE D P+P + E Sbjct: 500 VLPLVQKSTLADYS--AQKDLEPESDRSAQPLPLKIE 534 >gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] Length = 285 Score = 72.0 bits (175), Expect = 3e-12 Identities = 35/74 (47%), Positives = 56/74 (75%), Gaps = 2/74 (2%) Query: 320 SERMSGLSAERLQMDEELRRERERERERERE-READREREKEREREREKEREQEKERERE 378 +ER ER Q E RR+R+RER+RE+E RE DR+R+KERE++R +ERE ++R++E Sbjct: 169 TERYRDRERER-QKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKE 227 Query: 379 KERERELERQREQR 392 ++RER+ E+ R+++ Sbjct: 228 RDRERQREKDRDRQ 241 Score = 70.1 bits (170), Expect = 1e-11 Identities = 36/102 (35%), Positives = 66/102 (64%), Gaps = 2/102 (1%) Query: 299 LHLSGVRYPPELSHSSLAALHSERMSGLSAER-LQMDEELRREREREREREREREADRER 357 L L G R P + ER + ER + D E+ ++R+R+R+R+RER+ R+R Sbjct: 45 LILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDR 104 Query: 358 EKEREREREKEREQEKEREREKERERELERQRE-QRAREKEL 398 +++RER +++RE E ER+ E+ER+R+ +R+++ +R R++E+ Sbjct: 105 DRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREI 146 Score = 64.7 bits (156), Expect = 5e-10 Identities = 32/80 (40%), Positives = 55/80 (68%), Gaps = 11/80 (13%) Query: 329 ERLQMDEELRREREREREREREREADRER----EKERERERE-------KEREQEKERER 377 E + + +RE++RER+R+RE D++R EK+R+RERE ++RE+E++++R Sbjct: 124 EERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQR 183 Query: 378 EKERERELERQREQRAREKE 397 E R+R+ ERQRE+ RE++ Sbjct: 184 ETRRDRDRERQREKEDRERD 203 Score = 64.7 bits (156), Expect = 5e-10 Identities = 42/104 (40%), Positives = 66/104 (63%), Gaps = 20/104 (19%) Query: 321 ERMSGLSAERLQMDEELRRERERE-------REREREREADRE--REKEREREREKE--- 368 +R G+ +R +++ E R+RERE R+RERER+ RE R+++RER+REKE Sbjct: 143 QREIGIDKDR-EIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRE 201 Query: 369 --REQEKEREREKERERELERQRE-----QRAREKELLAAKALE 405 R+++KERE+++ RERE R R+ +R REK+ KA++ Sbjct: 202 RDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAID 245 Score = 62.4 bits (150), Expect = 3e-09 Identities = 28/65 (43%), Positives = 50/65 (76%), Gaps = 1/65 (1%) Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393 D + +RER +R+RE E E ERE++R+R+REK+RE++++RE +++RE+E +++ R Sbjct: 103 DRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKD-RD 161 Query: 394 REKEL 398 RE+E+ Sbjct: 162 REREM 166 Score = 62.4 bits (150), Expect = 3e-09 Identities = 35/84 (41%), Positives = 54/84 (64%), Gaps = 20/84 (23%) Query: 334 DEELRREREREREREREREADREREKERERE----REKEREQEKEREREKE--------- 380 D E ER+ ERER+R+R+ +++RE++R+RE +++E E EK+R+RE+E Sbjct: 115 DRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRD 174 Query: 381 RERELERQRE-------QRAREKE 397 RERE ++QRE +R REKE Sbjct: 175 RERERQKQRETRRDRDRERQREKE 198 Score = 60.5 bits (145), Expect = 1e-08 Identities = 27/64 (42%), Positives = 45/64 (70%) Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393 D + E ER+ ERER+R+ RE+++ER+R+RE ++++E E EK+R+RE E +R Sbjct: 113 DRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERY 172 Query: 394 REKE 397 R++E Sbjct: 173 RDRE 176 >gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo sapiens] Length = 142 Score = 71.2 bits (173), Expect = 5e-12 Identities = 42/101 (41%), Positives = 57/101 (56%), Gaps = 16/101 (15%) Query: 307 PPELSHSSLAALHSERMSGLSAERLQMDEELRRERER--EREREREREADREREKERERE 364 PP L HS M+G SA + Q EE RRE +R E+ RE +R + REKE E+E Sbjct: 50 PPTLRHS---------MAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKE 100 Query: 365 REKEREQEKEREREKERERELE-----RQREQRAREKELLA 400 E+E E+E+E E E+E E E+ R+RE EK L++ Sbjct: 101 EEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLIS 141 Score = 46.6 bits (109), Expect = 1e-04 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 3/80 (3%) Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERE---R 377 E ++GL+ + EE R + RE ++ E+ RE++R +EK RE R Sbjct: 34 ENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRR 93 Query: 378 EKERERELERQREQRAREKE 397 EKE E+E E + E+ E+E Sbjct: 94 EKEEEKEEEEEEEEEEEEEE 113 Score = 32.0 bits (71), Expect = 3.7 Identities = 13/30 (43%), Positives = 22/30 (73%) Query: 1089 RKGPPTQELDRDSEEEEEEDDEDGEDEEEV 1118 R+ ++ + + EEEEEE++E+ E+EEEV Sbjct: 92 RREKEEEKEEEEEEEEEEEEEEEEEEEEEV 121 Score = 31.6 bits (70), Expect = 4.8 Identities = 13/29 (44%), Positives = 21/29 (72%) Query: 1089 RKGPPTQELDRDSEEEEEEDDEDGEDEEE 1117 R+ +E + + EEEEEE++E+ E+EEE Sbjct: 87 RREGKRREKEEEKEEEEEEEEEEEEEEEE 115 Score = 31.6 bits (70), Expect = 4.8 Identities = 13/29 (44%), Positives = 21/29 (72%) Query: 1089 RKGPPTQELDRDSEEEEEEDDEDGEDEEE 1117 R+G ++ + EEEEEE++E+ E+EEE Sbjct: 88 REGKRREKEEEKEEEEEEEEEEEEEEEEE 116 Score = 30.8 bits (68), Expect = 8.2 Identities = 16/59 (27%), Positives = 32/59 (54%) Query: 1089 RKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQNLERQVL 1147 R+ +E R +EEE+E++E+ E+EEE + + + E F E + E++++ Sbjct: 82 RREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLI 140 >gi|125988409 RED protein [Homo sapiens] Length = 557 Score = 70.9 bits (172), Expect = 7e-12 Identities = 34/63 (53%), Positives = 48/63 (76%), Gaps = 2/63 (3%) Query: 327 SAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELE 386 S + D+E RER RERER+RER+ DR+RE+ERER+RE+ERE+++ERE EK+R E Sbjct: 328 STTKTPRDKE--RERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFE 385 Query: 387 RQR 389 + + Sbjct: 386 KPK 388 Score = 63.9 bits (154), Expect = 9e-10 Identities = 25/49 (51%), Positives = 44/49 (89%) Query: 345 REREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393 R++ERER +RER++ER+R+R++ERE+E++RERE+ER+RE E ++++ + Sbjct: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHS 382 Score = 61.2 bits (147), Expect = 6e-09 Identities = 24/46 (52%), Positives = 41/46 (89%) Query: 349 REREADREREKEREREREKEREQEKEREREKERERELERQREQRAR 394 R++E +R RE+ER+RER+++R++E+ERER++ERERE +R+RE+ + Sbjct: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKK 379 Score = 60.1 bits (144), Expect = 1e-08 Identities = 25/46 (54%), Positives = 39/46 (84%) Query: 351 READREREKEREREREKEREQEKEREREKERERELERQREQRAREK 396 R+ +RER +ERER+RE++R++++ERERE++RERE ER RE+ +K Sbjct: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKK 379 Score = 60.1 bits (144), Expect = 1e-08 Identities = 37/98 (37%), Positives = 57/98 (58%), Gaps = 8/98 (8%) Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393 + E RER+R+R+RERERE DRERE+ER+RERE+E+++ E+ K + ++ + Sbjct: 343 ERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGP-G 401 Query: 394 REKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQ 431 KEL+ K++ F A G TE KP ++ Sbjct: 402 STKELI--KSINEKFAGSAGWEG-----TESLKKPEDK 432 Score = 58.5 bits (140), Expect = 4e-08 Identities = 26/44 (59%), Positives = 40/44 (90%), Gaps = 1/44 (2%) Query: 354 DREREKEREREREKEREQEKEREREKERERELERQREQRAREKE 397 D+ERE+ RERER++ER+++++RERE+ER+RE ER+R+ R RE+E Sbjct: 335 DKERERYRERERDRERDRDRDRERERERDRERERERD-REREEE 377 Score = 35.4 bits (80), Expect = 0.33 Identities = 21/54 (38%), Positives = 30/54 (55%), Gaps = 1/54 (1%) Query: 343 REREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREK 396 + R E RE + E E R R+K+ K R++E EREREL + RA+E+ Sbjct: 54 KSRHHEMPREYN-EDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKER 106 Score = 32.7 bits (73), Expect = 2.2 Identities = 28/79 (35%), Positives = 41/79 (51%), Gaps = 4/79 (5%) Query: 339 RERERERE-REREREADREREKEREREREKEREQEKERE-REKERERELERQR--EQRAR 394 R E RE E E A R R+K+ + +++E E+ERE EK R+R ER+ + Sbjct: 56 RHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYE 115 Query: 395 EKELLAAKALEPSFLPVAE 413 E EL++ A + P AE Sbjct: 116 ETELISTTANYRAVGPTAE 134 >gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] Length = 1220 Score = 70.1 bits (170), Expect = 1e-11 Identities = 41/95 (43%), Positives = 61/95 (64%), Gaps = 4/95 (4%) Query: 309 ELSHSSLAALHSERMSGLSAERLQMDEELRRERER-EREREREREADREREKEREREREK 367 EL A L +R +L+ E+ R+ERER E+ER+R+ E +++ EK+RE ER++ Sbjct: 364 ELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQR 423 Query: 368 EREQEKEREREKERERELERQRE---QRAREKELL 399 E E+ KE ER + +RELERQR+ +R R +ELL Sbjct: 424 EEERRKEIERREAAKRELERQRQLEWERNRRQELL 458 Score = 56.6 bits (135), Expect = 1e-07 Identities = 42/119 (35%), Positives = 68/119 (57%), Gaps = 10/119 (8%) Query: 329 ERLQMDEELRRERERERER-EREREADREREKEREREREKEREQEKER----EREKERER 383 ER ++ E RR+ E++R E+ER A ER ++ +ERE++ EQE++R E++ E++R Sbjct: 359 ERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQ-EQERKRQLELEKQLEKQR 417 Query: 384 ELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATE---ERGKPSEQLTPTRAEK 439 ELERQRE+ R KE+ +A + +L R E +R K E + +A+K Sbjct: 418 ELERQREEE-RRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKK 475 Score = 54.7 bits (130), Expect = 5e-07 Identities = 40/131 (30%), Positives = 63/131 (48%), Gaps = 11/131 (8%) Query: 315 LAALHSERMSGLSAERLQMDE----ELRREREREREREREREADREREKEREREREKERE 370 LA L ER + + EL ++ E++RE ER+RE +R +E ER ++E E Sbjct: 383 LAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELE 442 Query: 371 QEKEREREKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSE 430 ++++ E E+ R +EL QR + + +L AK F EL L + GK + Sbjct: 443 RQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEF----ELEALNDKKHQLEGKLQD 498 Query: 431 ---QLTPTRAE 438 +LT R E Sbjct: 499 IRCRLTTQRQE 509 Score = 44.3 bits (103), Expect = 7e-04 Identities = 33/119 (27%), Positives = 61/119 (51%), Gaps = 9/119 (7%) Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380 ++ + AERL+ E+ R+ E E+++E EA R R +ER+++ + +QE E +R ++ Sbjct: 620 QKQKSMEAERLKQKEQERKIIELEKQKE---EAQR-RAQERDKQWLEHVQQEDEHQRPRK 675 Query: 381 RERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEK 439 E + +RE+ ++K+ E + G H +E KP+ Q + AEK Sbjct: 676 LHEEEKLKREESVKKKD-----GEEKGKQEAQDKLGRLFHQHQEPAKPAVQAPWSTAEK 729 Score = 42.0 bits (97), Expect = 0.004 Identities = 44/166 (26%), Positives = 75/166 (45%), Gaps = 30/166 (18%) Query: 296 AMHL---HLSGVRYPPEL-------------SHSSLAALHSERMSG-LSAERLQMDEELR 338 AMHL +SG PP L S S ++ + S + L E + DE+ + Sbjct: 282 AMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQ 341 Query: 339 RERE-----REREREREREADREREKEREREREKER-EQEKEREREKERERELERQREQR 392 E++ +++RE + E EK R+ E++R EQE+ + E+ + ER+R+++ Sbjct: 342 LEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQ 401 Query: 393 AREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAE 438 R+++L K LE + L EER K E+ + E Sbjct: 402 ERKRQLELEKQLE-------KQRELERQREEERRKEIERREAAKRE 440 Score = 33.9 bits (76), Expect = 0.97 Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 7/76 (9%) Query: 485 ALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQV-LEQHLDMGRPPVPAEAEHRPE 543 ALL Q+ E+E+ LA+ R QE+++R+ Q E ++Q+ LE+ L+ R E E + E Sbjct: 371 ALLEQQRKEQER-LAQLERAEQERKERERQEQERKRQLELEKQLEKQR-----ELERQRE 424 Query: 544 STTRPGPNRHEPGGRD 559 R R E R+ Sbjct: 425 EERRKEIERREAAKRE 440 Score = 33.5 bits (75), Expect = 1.3 Identities = 33/116 (28%), Positives = 61/116 (52%), Gaps = 11/116 (9%) Query: 1095 QELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQNLERQ---VLQTQC 1151 +EL+R EEE ++ E E + +R+ Q +E QE + ++N E++ VL+ + Sbjct: 417 RELERQREEERRKEIERREAAKRELERQRQ-LEWERNRRQELLNQRNKEQEDIVVLKAKK 475 Query: 1152 RRLEARHYSLSLTAEQLSHSVAELR----SQKQKMVS---ERERLQAELDHLRKCL 1200 + LE +L+ QL + ++R +Q+Q++ S RE AE+ HL++ L Sbjct: 476 KTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQL 531 Score = 33.1 bits (74), Expect = 1.7 Identities = 32/123 (26%), Positives = 56/123 (45%), Gaps = 24/123 (19%) Query: 330 RLQMDEELRRERERERERE---------REREADREREKEREREREKEREQEKER---ER 377 R Q+DE + R + +E + RE ++ +K++ E E+ +++E+ER E Sbjct: 583 RDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIEL 642 Query: 378 EKERERELERQREQRAREKELLAAKALEPSFLPVAELH---------GLRGHATEERGKP 428 EK++E E QR + R+K+ L E +LH ++ EE+GK Sbjct: 643 EKQKE---EAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQ 699 Query: 429 SEQ 431 Q Sbjct: 700 EAQ 702 >gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] Length = 1721 Score = 70.1 bits (170), Expect = 1e-11 Identities = 41/95 (43%), Positives = 61/95 (64%), Gaps = 4/95 (4%) Query: 309 ELSHSSLAALHSERMSGLSAERLQMDEELRRERER-EREREREREADREREKEREREREK 367 EL A L +R +L+ E+ R+ERER E+ER+R+ E +++ EK+RE ER++ Sbjct: 364 ELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQR 423 Query: 368 EREQEKEREREKERERELERQRE---QRAREKELL 399 E E+ KE ER + +RELERQR+ +R R +ELL Sbjct: 424 EEERRKEIERREAAKRELERQRQLEWERNRRQELL 458 Score = 56.6 bits (135), Expect = 1e-07 Identities = 42/119 (35%), Positives = 68/119 (57%), Gaps = 10/119 (8%) Query: 329 ERLQMDEELRRERERERER-EREREADREREKEREREREKEREQEKER----EREKERER 383 ER ++ E RR+ E++R E+ER A ER ++ +ERE++ EQE++R E++ E++R Sbjct: 359 ERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQ-EQERKRQLELEKQLEKQR 417 Query: 384 ELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATE---ERGKPSEQLTPTRAEK 439 ELERQRE+ R KE+ +A + +L R E +R K E + +A+K Sbjct: 418 ELERQREEE-RRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKK 475 Score = 54.7 bits (130), Expect = 5e-07 Identities = 40/131 (30%), Positives = 63/131 (48%), Gaps = 11/131 (8%) Query: 315 LAALHSERMSGLSAERLQMDE----ELRREREREREREREREADREREKEREREREKERE 370 LA L ER + + EL ++ E++RE ER+RE +R +E ER ++E E Sbjct: 383 LAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELE 442 Query: 371 QEKEREREKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSE 430 ++++ E E+ R +EL QR + + +L AK F EL L + GK + Sbjct: 443 RQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEF----ELEALNDKKHQLEGKLQD 498 Query: 431 ---QLTPTRAE 438 +LT R E Sbjct: 499 IRCRLTTQRQE 509 Score = 44.3 bits (103), Expect = 7e-04 Identities = 33/119 (27%), Positives = 61/119 (51%), Gaps = 9/119 (7%) Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380 ++ + AERL+ E+ R+ E E+++E EA R R +ER+++ + +QE E +R ++ Sbjct: 620 QKQKSMEAERLKQKEQERKIIELEKQKE---EAQR-RAQERDKQWLEHVQQEDEHQRPRK 675 Query: 381 RERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEK 439 E + +RE+ ++K+ E + G H +E KP+ Q + AEK Sbjct: 676 LHEEEKLKREESVKKKD-----GEEKGKQEAQDKLGRLFHQHQEPAKPAVQAPWSTAEK 729 Score = 42.0 bits (97), Expect = 0.004 Identities = 44/166 (26%), Positives = 75/166 (45%), Gaps = 30/166 (18%) Query: 296 AMHL---HLSGVRYPPEL-------------SHSSLAALHSERMSG-LSAERLQMDEELR 338 AMHL +SG PP L S S ++ + S + L E + DE+ + Sbjct: 282 AMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQ 341 Query: 339 RERE-----REREREREREADREREKEREREREKER-EQEKEREREKERERELERQREQR 392 E++ +++RE + E EK R+ E++R EQE+ + E+ + ER+R+++ Sbjct: 342 LEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQ 401 Query: 393 AREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAE 438 R+++L K LE + L EER K E+ + E Sbjct: 402 ERKRQLELEKQLE-------KQRELERQREEERRKEIERREAAKRE 440 Score = 33.9 bits (76), Expect = 0.97 Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 7/76 (9%) Query: 485 ALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQV-LEQHLDMGRPPVPAEAEHRPE 543 ALL Q+ E+E+ LA+ R QE+++R+ Q E ++Q+ LE+ L+ R E E + E Sbjct: 371 ALLEQQRKEQER-LAQLERAEQERKERERQEQERKRQLELEKQLEKQR-----ELERQRE 424 Query: 544 STTRPGPNRHEPGGRD 559 R R E R+ Sbjct: 425 EERRKEIERREAAKRE 440 Score = 33.5 bits (75), Expect = 1.3 Identities = 33/116 (28%), Positives = 61/116 (52%), Gaps = 11/116 (9%) Query: 1095 QELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQNLERQ---VLQTQC 1151 +EL+R EEE ++ E E + +R+ Q +E QE + ++N E++ VL+ + Sbjct: 417 RELERQREEERRKEIERREAAKRELERQRQ-LEWERNRRQELLNQRNKEQEDIVVLKAKK 475 Query: 1152 RRLEARHYSLSLTAEQLSHSVAELR----SQKQKMVS---ERERLQAELDHLRKCL 1200 + LE +L+ QL + ++R +Q+Q++ S RE AE+ HL++ L Sbjct: 476 KTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQL 531 Score = 33.1 bits (74), Expect = 1.7 Identities = 32/123 (26%), Positives = 56/123 (45%), Gaps = 24/123 (19%) Query: 330 RLQMDEELRRERERERERE---------REREADREREKEREREREKEREQEKER---ER 377 R Q+DE + R + +E + RE ++ +K++ E E+ +++E+ER E Sbjct: 583 RDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIEL 642 Query: 378 EKERERELERQREQRAREKELLAAKALEPSFLPVAELH---------GLRGHATEERGKP 428 EK++E E QR + R+K+ L E +LH ++ EE+GK Sbjct: 643 EKQKE---EAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQ 699 Query: 429 SEQ 431 Q Sbjct: 700 EAQ 702 >gi|34878777 ring finger protein 20 [Homo sapiens] Length = 975 Score = 70.1 bits (170), Expect = 1e-11 Identities = 40/100 (40%), Positives = 58/100 (58%), Gaps = 1/100 (1%) Query: 307 PPELSHSSLAALHSERMSGLSAERLQMDEELRRERERERER-EREREADREREKERERER 365 P EL S S S E + R E ERERER E+ERE +REREKE+ERER Sbjct: 533 PAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKEREREREREKEKERER 592 Query: 366 EKEREQEKEREREKERERELERQREQRAREKELLAAKALE 405 EK++ +E E+ER+ +++E + + R +E E++ +E Sbjct: 593 EKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKIE 632 Score = 55.8 bits (133), Expect = 2e-07 Identities = 43/149 (28%), Positives = 69/149 (46%), Gaps = 30/149 (20%) Query: 311 SHSSLAALHSERMSGLSAERLQMDEEL-RREREREREREREREADREREKEREREREKER 369 S SS + E + + ++R + + E RRE+ERERERERE+E +REREK++ +E EKER Sbjct: 545 SQSSASKASQEDANEIKSKRDEEERERERREKEREREREREKEKEREREKQKLKESEKER 604 Query: 370 EQEKER---------------------------EREKERERELERQREQRAREKELLAAK 402 + K++ E +KE + L+ R +++ + Sbjct: 605 DSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLM 664 Query: 403 ALEPSFLPVAELHGLRGHATEERGKPSEQ 431 A E AEL LR + K ++ Sbjct: 665 AAEKK--SKAELEDLRQRLKDLEDKEKKE 691 Score = 33.9 bits (76), Expect = 0.97 Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 7/97 (7%) Query: 304 VRYPPELSHSSLAALHSERMSGLSAERLQMDEELRRERERERERERE---READREREKE 360 +RY +L + + SG + + Q E ++ E + + E ++ + + Sbjct: 495 LRYKRKLREAQSDLNKTRLRSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKASQ 554 Query: 361 REREREKEREQEKEREREKERERELERQREQRAREKE 397 + K + E+ERERE+ RE ER+RE R REKE Sbjct: 555 EDANEIKSKRDEEERERER---REKERERE-REREKE 587 Score = 33.9 bits (76), Expect = 0.97 Identities = 31/133 (23%), Positives = 54/133 (40%), Gaps = 4/133 (3%) Query: 321 ERMSGLSAERLQMDEELRRER---EREREREREREADREREKEREREREKEREQEKE-RE 376 E S L+ RL+ L + + E ++ E + D E + + +E E + Sbjct: 503 EAQSDLNKTRLRSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKS 562 Query: 377 REKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTR 436 + E ERE ER+ ++R RE+E K E + E R A ++ + Sbjct: 563 KRDEEERERERREKEREREREREKEKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKE 622 Query: 437 AEKLKDAGLQAPK 449 AE +K ++ K Sbjct: 623 AEIIKQLKIELKK 635 Score = 31.6 bits (70), Expect = 4.8 Identities = 29/145 (20%), Positives = 64/145 (44%), Gaps = 11/145 (7%) Query: 1066 PELQSSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQG 1125 P+ + S Q++ + +E +R+ E+E E + + E E+E + K + Sbjct: 538 PDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKEREREREREKEKEREREKQKL 597 Query: 1126 IEAVFEAYQ-------EHIEEQNLERQV---LQTQCRRLEARHYSLSLTAEQLSHSVAEL 1175 E+ E +H + + E ++ L+ + ++ + + L + + E Sbjct: 598 KESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQ 657 Query: 1176 RSQKQKMVSERERLQAELDHLRKCL 1200 R + Q M +E+ + +AEL+ LR+ L Sbjct: 658 RDKVQLMAAEK-KSKAELEDLRQRL 681 >gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4 isoform 2 [Homo sapiens] Length = 1320 Score = 70.1 bits (170), Expect = 1e-11 Identities = 67/234 (28%), Positives = 104/234 (44%), Gaps = 32/234 (13%) Query: 315 LAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKE 374 L A +R+ +R +++E+ RRERE R++ERE+ + EK R E E+ R++E+E Sbjct: 391 LLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEE 450 Query: 375 REREKERERELERQRE--QRAREKELLAAKALEPSFL-PVAELHGLRGHATEERGKPSEQ 431 R R +E +R +ER++E +R E+E + L+ L A L R EE + Sbjct: 451 RRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERL 510 Query: 432 LTPTRAEKLKDAGLQAPKPVQHPLH----PVPTPHHTVPSLISNHGIFSLPSSSAATALL 487 + E+ LQ HP H P P + PS F P A Sbjct: 511 QRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPS-------FHAPEPKA----- 558 Query: 488 IQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQ--QVLEQHLDMGRPPVPAEAE 539 + E AR+ R K + S ++ +Q +VLE PPVP+ +E Sbjct: 559 ----HYEPADRAREVEDRFRKTNHSSPEAQSKQTGRVLE-------PPVPSRSE 601 Score = 54.3 bits (129), Expect = 7e-07 Identities = 25/78 (32%), Positives = 48/78 (61%) Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERERE 378 + ER L ++L +++LR + E +R+ ER+ E++KE+ R E+++ +E+E R+ Sbjct: 363 NKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQ 422 Query: 379 KERERELERQREQRAREK 396 +ERE+ Q E+R E+ Sbjct: 423 QEREQRRREQEEKRRLEE 440 Score = 53.1 bits (126), Expect = 2e-06 Identities = 24/68 (35%), Positives = 44/68 (64%) Query: 330 RLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQR 389 +L + + R E+++E+ R E + RERE R++ERE+ R +++E+ R +E ER + + Sbjct: 390 QLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEE 449 Query: 390 EQRAREKE 397 E+R E+E Sbjct: 450 ERRRAEEE 457 Score = 51.2 bits (121), Expect = 6e-06 Identities = 58/237 (24%), Positives = 97/237 (40%), Gaps = 34/237 (14%) Query: 326 LSAERLQMDEELRREREREREREREREA-DREREKEREREREKEREQEKEREREKERERE 384 L E + E LRR++ + ++ RE+E R+ ER++ E+++EQ + E ++ RERE Sbjct: 359 LQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRRERE 418 Query: 385 LERQ--REQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKD 442 RQ REQR RE+E + LE EL R E R RAE+ K Sbjct: 419 ARRQQEREQRRREQE--EKRRLE-------ELERRRKEEEERR----------RAEEEKR 459 Query: 443 AGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQR 502 + + ++ L + + A+L++ E + + Sbjct: 460 RVEREQEYIRRQLEEEQRHLEVLQQQLLQE-----------QAMLLECRWREMEEHRQAE 508 Query: 503 RLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRH-EPGGR 558 RL+++ + Q+ + + H + P P + E S P P H EP R Sbjct: 509 RLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADR 565 Score = 50.8 bits (120), Expect = 8e-06 Identities = 26/79 (32%), Positives = 47/79 (59%), Gaps = 3/79 (3%) Query: 322 RMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERE---RE 378 R L ++L+ EE +R+ ER++ E++ ++ R E ++ RE+E +++ERE RE Sbjct: 372 RQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRRE 431 Query: 379 KERERELERQREQRAREKE 397 +E +R LE +R E+E Sbjct: 432 QEEKRRLEELERRRKEEEE 450 Score = 38.1 bits (87), Expect = 0.051 Identities = 65/273 (23%), Positives = 105/273 (38%), Gaps = 27/273 (9%) Query: 731 QQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDE----EEVRAHLRCVAEQPPLKL 786 Q+R R + E+RRRE +EK +L+ E +E EE + + E +L Sbjct: 413 QRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQL 472 Query: 787 DTSSEKLEFLQLFGLTTQ------QQKEELVAQKRRKRRRMLRERSPSPPTIQSKRQTPS 840 + LE LQ L Q + +E ++ + +R L++ ++Q + P Sbjct: 473 EEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPH 532 Query: 841 PRLALSTRYSPDEMNNSPNF---EEKKKFLTIFNLTHISAEKRKDKERLVEMLRAMKQKA 897 P+ + P + + P+F E K + + RK E + Sbjct: 533 PQHSQQPP-PPQQERSKPSFHAPEPKAHYEPADRAREVEDRFRKTNHSSPEAQSKQTGRV 591 Query: 898 LSAAV---ADSLTNSPRDSPAVSLSEPATQQ------ASL-DVEKPVGVAASLSDIPKAA 947 L V ++S +N +S +L PA Q ASL + PV + S SD Sbjct: 592 LEPPVPSRSESFSNGNSESVHPALQRPAEPQVQWSHLASLKNNVSPVSRSHSFSDPSPKF 651 Query: 948 EPGKLEQVRPQELSRVQELAPASGEKARLSEAP 980 L P SR + L+ +S K SEAP Sbjct: 652 AHHHLRSQDPCPPSRSEVLSQSSDSK---SEAP 681 Score = 35.0 bits (79), Expect = 0.44 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 16/125 (12%) Query: 1082 QQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHI---- 1137 Q+ AR+ ++ R+ EE+ ++ + +EE +R+ + + E QE+I Sbjct: 413 QRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQL 472 Query: 1138 -EEQN----LERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERERLQAE 1192 EEQ L++Q+LQ Q LE R E H AE R Q+Q + L + Sbjct: 473 EEEQRHLEVLQQQLLQEQAMLLECR------WREMEEHRQAE-RLQRQLQQEQAYLLSLQ 525 Query: 1193 LDHLR 1197 DH R Sbjct: 526 HDHRR 530 Score = 31.2 bits (69), Expect = 6.3 Identities = 27/116 (23%), Positives = 48/116 (41%), Gaps = 4/116 (3%) Query: 1079 HNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIE 1138 H + K E EEEEE +++GE V + F Q+ + Sbjct: 305 HIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENK 364 Query: 1139 EQN--LERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERERLQAE 1192 E++ L RQ L + + E Y L AE+ E + ++++ + E++R + E Sbjct: 365 ERSEALRRQQLLQEQQLREQEEYKRQLLAERQKR--IEQQKEQRRRLEEQQRRERE 418 >gi|14670268 RD RNA-binding protein [Homo sapiens] Length = 380 Score = 68.9 bits (167), Expect = 3e-11 Identities = 26/58 (44%), Positives = 49/58 (84%) Query: 340 EREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKE 397 ER R+R+R+RER+ DR+R+++RER+R+++R+++++RER+++RER+ +R RE R + Sbjct: 193 ERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSD 250 Score = 67.8 bits (164), Expect = 6e-11 Identities = 27/73 (36%), Positives = 52/73 (71%) Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERERE 378 + ER S+ R ER R+R+R+RE DR+R+++R+RER+++R+++++R+RE Sbjct: 170 YEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRE 229 Query: 379 KERERELERQREQ 391 ++R+RE +R R++ Sbjct: 230 RDRDRERDRDRDR 242 Score = 67.4 bits (163), Expect = 8e-11 Identities = 24/55 (43%), Positives = 48/55 (87%) Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQ 388 D R R+R+R+RER+R+ DR+R++ER+R+R+++R++++ER+R++ER+R+ +R+ Sbjct: 189 DRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243 Score = 62.4 bits (150), Expect = 3e-09 Identities = 30/86 (34%), Positives = 54/86 (62%), Gaps = 1/86 (1%) Query: 311 SHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKERE 370 +HSS + S D + R+R+R+R+R+RER+ DR+R+++R+RER+++RE Sbjct: 176 AHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRE 235 Query: 371 QEKEREREKERERELERQREQRAREK 396 ++++R+RE R + E+RA K Sbjct: 236 RDRDRDREGPFRRS-DSFPERRAPRK 260 Score = 60.5 bits (145), Expect = 1e-08 Identities = 26/76 (34%), Positives = 49/76 (64%) Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393 D E R+R+R+R+RER+R+ DR+R+++RER+R++ER+++++RE R +R R Sbjct: 201 DRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRK 260 Query: 394 REKELLAAKALEPSFL 409 + + + P+ L Sbjct: 261 GNTLYVYGEDMTPTLL 276 >gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain containing B [Homo sapiens] Length = 546 Score = 68.2 bits (165), Expect = 5e-11 Identities = 41/82 (50%), Positives = 51/82 (62%), Gaps = 8/82 (9%) Query: 321 ERMSGLSAER-LQMDEELRREREREREREREREADR-----EREKEREREREKEREQEKE 374 ER S +R L+ RER R R R R+R+ DR EREKE ER R ++R+ +KE Sbjct: 314 ERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKE 373 Query: 375 R--EREKERERELERQREQRAR 394 R EREKERER ER +EQR+R Sbjct: 374 RGNEREKERERSRERSKEQRSR 395 Score = 61.6 bits (148), Expect = 4e-09 Identities = 30/75 (40%), Positives = 46/75 (61%) Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380 ER S R + + R+RERE+E ER R DR+ +KER EREKERE+ +ER +E+ Sbjct: 334 ERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQR 393 Query: 381 RERELERQREQRARE 395 E+E ++ + ++ Sbjct: 394 SRGEVEEKKHKEDKD 408 Score = 60.1 bits (144), Expect = 1e-08 Identities = 30/77 (38%), Positives = 45/77 (58%) Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380 ER S ER + R + R+R+RERE + ER + R+R+ +KER E+E+ERE+ Sbjct: 326 ERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERS 385 Query: 381 RERELERQREQRAREKE 397 RER E++ EK+ Sbjct: 386 RERSKEQRSRGEVEEKK 402 Score = 56.6 bits (135), Expect = 1e-07 Identities = 37/126 (29%), Positives = 62/126 (49%), Gaps = 2/126 (1%) Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERER- 377 H R + + D + RE+E ER R R+R+ D+ER ERE+ERE+ RE+ KE+ Sbjct: 336 HRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSR 395 Query: 378 -EKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTR 436 E E ++ E + ++R R+ + + K + S E + GK S + + Sbjct: 396 GEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEK 455 Query: 437 AEKLKD 442 + K K+ Sbjct: 456 SSKHKN 461 Score = 53.1 bits (126), Expect = 2e-06 Identities = 31/82 (37%), Positives = 44/82 (53%), Gaps = 4/82 (4%) Query: 319 HSERMSGLSAER-LQMDEELRREREREREREREREADREREKEREREREKEREQEKERER 377 H ER S R L RR R R RE + +RE ERE+ER++ + KERE+ Sbjct: 254 HVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREK 313 Query: 378 EKERERELER---QREQRAREK 396 E+ R R ++R +R R+RE+ Sbjct: 314 ERRRSRSIDRGLERRRSRSRER 335 Score = 45.8 bits (107), Expect = 2e-04 Identities = 33/100 (33%), Positives = 47/100 (47%), Gaps = 9/100 (9%) Query: 335 EELRREREREREREREREADREREKEREREREKEREQ------EKEREREKERERELERQ 388 EE+ R ER R R R R R R R RE ++E EREKER+R LER+ Sbjct: 249 EEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQR-LERE 307 Query: 389 REQRAREKELLAA--KALEPSFLPVAELHGLRGHATEERG 426 ++R +E+ + + LE E H R + + +G Sbjct: 308 AKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKG 347 Score = 38.5 bits (88), Expect = 0.039 Identities = 18/56 (32%), Positives = 34/56 (60%), Gaps = 4/56 (7%) Query: 346 EREREREADREREKEREREREKEREQEKEREREKERERELERQR----EQRAREKE 397 E+ ++RE +EK R+R R KER +++ K++ + +R+R EQ ++EK+ Sbjct: 483 EKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQ 538 Score = 38.1 bits (87), Expect = 0.051 Identities = 20/63 (31%), Positives = 30/63 (47%) Query: 335 EELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAR 394 +E E +R ER R R R R R + R +E +RELER++E++ Sbjct: 245 KEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRL 304 Query: 395 EKE 397 E+E Sbjct: 305 ERE 307 Score = 37.4 bits (85), Expect = 0.088 Identities = 16/72 (22%), Positives = 36/72 (50%) Query: 324 SGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERER 383 SG +++ +RE +E+ R+R +ER +R+ K++ + +R R + E+ Sbjct: 473 SGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQ 532 Query: 384 ELERQREQRARE 395 E + ++ + E Sbjct: 533 ESQEKQHKNKDE 544 Score = 37.0 bits (84), Expect = 0.11 Identities = 18/65 (27%), Positives = 40/65 (61%), Gaps = 2/65 (3%) Query: 334 DEELRREREREREREREREADREREKERE-REREKEREQEKE-REREKERERELERQREQ 391 D++ RR R+ +R+ ++E++ R R +ER+ R R + R K R R KE+ + + + ++ Sbjct: 406 DKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKE 465 Query: 392 RAREK 396 ++ ++ Sbjct: 466 KSNKR 470 Score = 36.2 bits (82), Expect = 0.20 Identities = 11/63 (17%), Positives = 35/63 (55%) Query: 335 EELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAR 394 + + + ++RE +E+ R R KER +R+ +++ + ++ R + +E++ +++ Sbjct: 480 DSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQH 539 Query: 395 EKE 397 + + Sbjct: 540 KNK 542 Score = 35.0 bits (79), Expect = 0.44 Identities = 17/76 (22%), Positives = 34/76 (44%) Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380 E+ S E + E+ R R+ +R+ ++E R + RER+ +R + Sbjct: 391 EQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRS 450 Query: 381 RERELERQREQRAREK 396 R +E + + ++EK Sbjct: 451 RSKEKSSKHKNESKEK 466 Score = 34.3 bits (77), Expect = 0.74 Identities = 18/79 (22%), Positives = 34/79 (43%) Query: 309 ELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKE 368 E H S + + S + + + +E+ +R R R E+ ++RE Sbjct: 432 ERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHS 491 Query: 369 REQEKEREREKERERELER 387 +EK R+R + +ER +R Sbjct: 492 PSKEKSRKRSRSKERSHKR 510 Score = 33.9 bits (76), Expect = 0.97 Identities = 17/76 (22%), Positives = 34/76 (44%) Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380 +R S E+ + +E+ +R R + EK ++RE +E+ ++R R KE Sbjct: 446 KRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKE 505 Query: 381 RERELERQREQRAREK 396 R + + + +K Sbjct: 506 RSHKRDHSDSKDQSDK 521 Score = 31.2 bits (69), Expect = 6.3 Identities = 26/105 (24%), Positives = 42/105 (40%), Gaps = 4/105 (3%) Query: 335 EELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAR 394 +E + R R RER+ + +R R R KE+ K + KE+ + R Q R Sbjct: 421 KEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEK-SSKHKNESKEKSNKRSRSGSQ-GR 478 Query: 395 EKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEK 439 + +K E S P E R + E K + +++K Sbjct: 479 TDSVEKSKKREHS--PSKEKSRKRSRSKERSHKRDHSDSKDQSDK 521 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.128 0.370 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 60,642,780 Number of Sequences: 37866 Number of extensions: 3913930 Number of successful extensions: 93243 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1071 Number of HSP's successfully gapped in prelim test: 1451 Number of HSP's that attempted gapping in prelim test: 30701 Number of HSP's gapped (non-prelim): 31730 length of query: 1217 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1103 effective length of database: 13,930,794 effective search space: 15365665782 effective search space used: 15365665782 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.