Guide to the Human Genome
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Search of human proteins with 44955926

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|44955926 genetic suppressor element 1 isoform 1 [Homo
sapiens]
         (1217 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens]    2443   0.0  
gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens]   2246   0.0  
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                96   3e-19
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             93   2e-18
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        90   1e-17
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    86   2e-16
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         81   5e-15
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]            79   3e-14
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]         79   3e-14
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    77   8e-14
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    77   8e-14
gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens]                      77   1e-13
gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens]                       77   1e-13
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]            77   1e-13
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          75   3e-13
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          75   3e-13
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          75   3e-13
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti...    74   6e-13
gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens]                      74   6e-13
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    74   8e-13
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    73   2e-12
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]            72   3e-12
gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo ...    71   5e-12
gi|125988409 RED protein [Homo sapiens]                                71   7e-12
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]                70   1e-11
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]                70   1e-11
gi|34878777 ring finger protein 20 [Homo sapiens]                      70   1e-11
gi|22035604 mitogen-activated protein kinase kinase kinase kinas...    70   1e-11
gi|14670268 RD RNA-binding protein [Homo sapiens]                      69   3e-11
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ...    68   5e-11

>gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens]
          Length = 1217

 Score = 2443 bits (6332), Expect = 0.0
 Identities = 1217/1217 (100%), Positives = 1217/1217 (100%)

Query: 1    MKGMSHEPKSPSLGMLSTATRTTATVNPLTPSPLNGALVPSGSPATSSALSAQAAPSSSF 60
            MKGMSHEPKSPSLGMLSTATRTTATVNPLTPSPLNGALVPSGSPATSSALSAQAAPSSSF
Sbjct: 1    MKGMSHEPKSPSLGMLSTATRTTATVNPLTPSPLNGALVPSGSPATSSALSAQAAPSSSF 60

Query: 61   AAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPST 120
            AAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPST
Sbjct: 61   AAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPST 120

Query: 121  PPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQEKAGGPAIPSHLLSTP 180
            PPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQEKAGGPAIPSHLLSTP
Sbjct: 121  PPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQEKAGGPAIPSHLLSTP 180

Query: 181  YPFGLSPSSVVQDSRFPPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTTDDLRMSSLPPLG 240
            YPFGLSPSSVVQDSRFPPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTTDDLRMSSLPPLG
Sbjct: 181  YPFGLSPSSVVQDSRFPPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTTDDLRMSSLPPLG 240

Query: 241  LDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLH 300
            LDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLH
Sbjct: 241  LDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLH 300

Query: 301  LSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKE 360
            LSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKE
Sbjct: 301  LSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKE 360

Query: 361  REREREKEREQEKEREREKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGH 420
            REREREKEREQEKEREREKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGH
Sbjct: 361  REREREKEREQEKEREREKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGH 420

Query: 421  ATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSS 480
            ATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSS
Sbjct: 421  ATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSS 480

Query: 481  SAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEH 540
            SAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEH
Sbjct: 481  SAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEH 540

Query: 541  RPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQLHAAPTALWNPVSLMDNTLETRRA 600
            RPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQLHAAPTALWNPVSLMDNTLETRRA
Sbjct: 541  RPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQLHAAPTALWNPVSLMDNTLETRRA 600

Query: 601  ESHSLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPAPLDKYQPPPPPPREGG 660
            ESHSLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPAPLDKYQPPPPPPREGG
Sbjct: 601  ESHSLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPAPLDKYQPPPPPPREGG 660

Query: 661  SLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSGPLKPGSPYRPPVPRAP 720
            SLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSGPLKPGSPYRPPVPRAP
Sbjct: 661  SLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSGPLKPGSPYRPPVPRAP 720

Query: 721  DPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAE 780
            DPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAE
Sbjct: 721  DPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAE 780

Query: 781  QPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPTIQSKRQTPS 840
            QPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPTIQSKRQTPS
Sbjct: 781  QPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPTIQSKRQTPS 840

Query: 841  PRLALSTRYSPDEMNNSPNFEEKKKFLTIFNLTHISAEKRKDKERLVEMLRAMKQKALSA 900
            PRLALSTRYSPDEMNNSPNFEEKKKFLTIFNLTHISAEKRKDKERLVEMLRAMKQKALSA
Sbjct: 841  PRLALSTRYSPDEMNNSPNFEEKKKFLTIFNLTHISAEKRKDKERLVEMLRAMKQKALSA 900

Query: 901  AVADSLTNSPRDSPAVSLSEPATQQASLDVEKPVGVAASLSDIPKAAEPGKLEQVRPQEL 960
            AVADSLTNSPRDSPAVSLSEPATQQASLDVEKPVGVAASLSDIPKAAEPGKLEQVRPQEL
Sbjct: 901  AVADSLTNSPRDSPAVSLSEPATQQASLDVEKPVGVAASLSDIPKAAEPGKLEQVRPQEL 960

Query: 961  SRVQELAPASGEKARLSEAPGGKKSLSMLHYIRGAAPKDIPVPLSHSTNGKSKPWEPFVA 1020
            SRVQELAPASGEKARLSEAPGGKKSLSMLHYIRGAAPKDIPVPLSHSTNGKSKPWEPFVA
Sbjct: 961  SRVQELAPASGEKARLSEAPGGKKSLSMLHYIRGAAPKDIPVPLSHSTNGKSKPWEPFVA 1020

Query: 1021 EEFAHQFHESVLQSTQKALQKHKGSVAVLSAEQNHKVDTSVHYNIPELQSSSRAPPPQHN 1080
            EEFAHQFHESVLQSTQKALQKHKGSVAVLSAEQNHKVDTSVHYNIPELQSSSRAPPPQHN
Sbjct: 1021 EEFAHQFHESVLQSTQKALQKHKGSVAVLSAEQNHKVDTSVHYNIPELQSSSRAPPPQHN 1080

Query: 1081 GQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQ 1140
            GQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQ
Sbjct: 1081 GQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQ 1140

Query: 1141 NLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERERLQAELDHLRKCL 1200
            NLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERERLQAELDHLRKCL
Sbjct: 1141 NLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERERLQAELDHLRKCL 1200

Query: 1201 ALPAMHWPRGYLKGYPR 1217
            ALPAMHWPRGYLKGYPR
Sbjct: 1201 ALPAMHWPRGYLKGYPR 1217


>gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens]
          Length = 1113

 Score = 2246 bits (5821), Expect = 0.0
 Identities = 1113/1113 (100%), Positives = 1113/1113 (100%)

Query: 105  MGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQ 164
            MGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQ
Sbjct: 1    MGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQ 60

Query: 165  EKAGGPAIPSHLLSTPYPFGLSPSSVVQDSRFPPLNLQRPVHHVVPPSTVTEDYLRSFRP 224
            EKAGGPAIPSHLLSTPYPFGLSPSSVVQDSRFPPLNLQRPVHHVVPPSTVTEDYLRSFRP
Sbjct: 61   EKAGGPAIPSHLLSTPYPFGLSPSSVVQDSRFPPLNLQRPVHHVVPPSTVTEDYLRSFRP 120

Query: 225  YHTTDDLRMSSLPPLGLDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIP 284
            YHTTDDLRMSSLPPLGLDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIP
Sbjct: 121  YHTTDDLRMSSLPPLGLDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIP 180

Query: 285  TPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRRERERE 344
            TPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRRERERE
Sbjct: 181  TPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRRERERE 240

Query: 345  REREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKELLAAKAL 404
            REREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKELLAAKAL
Sbjct: 241  REREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKELLAAKAL 300

Query: 405  EPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVPTPHHT 464
            EPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVPTPHHT
Sbjct: 301  EPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVPTPHHT 360

Query: 465  VPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLE 524
            VPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLE
Sbjct: 361  VPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLE 420

Query: 525  QHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQLHAAPTAL 584
            QHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQLHAAPTAL
Sbjct: 421  QHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQLHAAPTAL 480

Query: 585  WNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPA 644
            WNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPA
Sbjct: 481  WNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPA 540

Query: 645  PLDKYQPPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSG 704
            PLDKYQPPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSG
Sbjct: 541  PLDKYQPPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSG 600

Query: 705  PLKPGSPYRPPVPRAPDPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYD 764
            PLKPGSPYRPPVPRAPDPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYD
Sbjct: 601  PLKPGSPYRPPVPRAPDPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYD 660

Query: 765  ESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRE 824
            ESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRE
Sbjct: 661  ESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRE 720

Query: 825  RSPSPPTIQSKRQTPSPRLALSTRYSPDEMNNSPNFEEKKKFLTIFNLTHISAEKRKDKE 884
            RSPSPPTIQSKRQTPSPRLALSTRYSPDEMNNSPNFEEKKKFLTIFNLTHISAEKRKDKE
Sbjct: 721  RSPSPPTIQSKRQTPSPRLALSTRYSPDEMNNSPNFEEKKKFLTIFNLTHISAEKRKDKE 780

Query: 885  RLVEMLRAMKQKALSAAVADSLTNSPRDSPAVSLSEPATQQASLDVEKPVGVAASLSDIP 944
            RLVEMLRAMKQKALSAAVADSLTNSPRDSPAVSLSEPATQQASLDVEKPVGVAASLSDIP
Sbjct: 781  RLVEMLRAMKQKALSAAVADSLTNSPRDSPAVSLSEPATQQASLDVEKPVGVAASLSDIP 840

Query: 945  KAAEPGKLEQVRPQELSRVQELAPASGEKARLSEAPGGKKSLSMLHYIRGAAPKDIPVPL 1004
            KAAEPGKLEQVRPQELSRVQELAPASGEKARLSEAPGGKKSLSMLHYIRGAAPKDIPVPL
Sbjct: 841  KAAEPGKLEQVRPQELSRVQELAPASGEKARLSEAPGGKKSLSMLHYIRGAAPKDIPVPL 900

Query: 1005 SHSTNGKSKPWEPFVAEEFAHQFHESVLQSTQKALQKHKGSVAVLSAEQNHKVDTSVHYN 1064
            SHSTNGKSKPWEPFVAEEFAHQFHESVLQSTQKALQKHKGSVAVLSAEQNHKVDTSVHYN
Sbjct: 901  SHSTNGKSKPWEPFVAEEFAHQFHESVLQSTQKALQKHKGSVAVLSAEQNHKVDTSVHYN 960

Query: 1065 IPELQSSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQ 1124
            IPELQSSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQ
Sbjct: 961  IPELQSSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQ 1020

Query: 1125 GIEAVFEAYQEHIEEQNLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVS 1184
            GIEAVFEAYQEHIEEQNLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVS
Sbjct: 1021 GIEAVFEAYQEHIEEQNLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVS 1080

Query: 1185 ERERLQAELDHLRKCLALPAMHWPRGYLKGYPR 1217
            ERERLQAELDHLRKCLALPAMHWPRGYLKGYPR
Sbjct: 1081 ERERLQAELDHLRKCLALPAMHWPRGYLKGYPR 1113


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 95.5 bits (236), Expect = 3e-19
 Identities = 100/365 (27%), Positives = 162/365 (44%), Gaps = 58/365 (15%)

Query: 321 ERMSGLSAERLQMDEELR-REREREREREREREADREREKEREREREKEREQEKEREREK 379
           ER S  + +R +  E+ R RERERERERERERE +RERE+ERERERE+ERE+E+E+++++
Sbjct: 372 ERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKR 431

Query: 380 ERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEK 439
           +RE + E   E+R  E++L   +A     L   E+   +   T E  K +E+    R E 
Sbjct: 432 DREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERK--KTREYEKEAEREEERRREM 489

Query: 440 LKDAGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLA 499
            K+A     K ++  L                      P     +AL  +  + E++  A
Sbjct: 490 AKEA-----KRLKEFLEDYDDDRDD-------------PKYYRGSALQKRLRDREKEMEA 531

Query: 500 RQRRLRQEKED----RQSQVSE------FRQQVLEQHLDMGRPP---VPAEAEHRPESTT 546
            +R  ++EKE+    RQ  ++E         Q +EQ  +  R P      E+E   E   
Sbjct: 532 DERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQ 591

Query: 547 RPGPNRHEP-GGRDPPQHFGGPPPLISPKPQLHAAPTALWN----------PVSLM---D 592
                R EP    + P+      P + P     +  +A  N          P  ++   +
Sbjct: 592 EKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDESPCGIIIPHE 651

Query: 593 NTLETRRAESH----------SLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKRE 642
           N+ + ++ E H             + P      ++  +P+  V   F  E +++ PRKR+
Sbjct: 652 NSPDQQQPEEHRPKIGLSLKLGASNSPGQPNSVKRKKLPVDSVFNKFEDEDSDDVPRKRK 711

Query: 643 PAPLD 647
             PLD
Sbjct: 712 LVPLD 716



 Score = 84.3 bits (207), Expect = 6e-16
 Identities = 45/77 (58%), Positives = 59/77 (76%), Gaps = 2/77 (2%)

Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380
           E   G   +  Q  E+ RRERERERERERER  +RERE+EREREREKE+E+E+ERER+++
Sbjct: 292 EEEKGKKEKERQEIEKERRERERERERERERR-EREREREREREREKEKERERERERDRD 350

Query: 381 RERELERQREQRAREKE 397
           R+R  ER R+ R RE++
Sbjct: 351 RDRTKERDRD-RDRERD 366



 Score = 80.5 bits (197), Expect = 9e-15
 Identities = 41/72 (56%), Positives = 62/72 (86%), Gaps = 3/72 (4%)

Query: 329 ERLQMDEELR-RERERERERE-REREADREREKEREREREKEREQEKEREREKERERELE 386
           ER ++++E R RERERERERE RERE +RERE+ERE+E+E+ERE+E++R+R++ +ER+ +
Sbjct: 301 ERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRD 360

Query: 387 RQREQ-RAREKE 397
           R RE+ R R++E
Sbjct: 361 RDRERDRDRDRE 372



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 33/81 (40%), Positives = 56/81 (69%), Gaps = 2/81 (2%)

Query: 318 LHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQ-EKERE 376
           +  ++   +S E  +  +  ++  E + ++E+ER+   +  +ERERERE+ERE+ E+ERE
Sbjct: 269 MEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERE 328

Query: 377 REKERERELERQREQRAREKE 397
           RE+ERERE E++RE R RE++
Sbjct: 329 REREREREKEKERE-RERERD 348



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 52/211 (24%), Positives = 87/211 (41%), Gaps = 26/211 (12%)

Query: 317 ALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKE-- 374
           A + ER+        +   E  +E ERE ER RE   + +R KE   + + +R+  K   
Sbjct: 455 AAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYR 514

Query: 375 ----REREKERERELERQREQRAREKELLAAKALEPSFL------PVAELHGLRGHATEE 424
               ++R ++RE+E+E     R REKE L  + +    L      P AEL  +   A   
Sbjct: 515 GSALQKRLRDREKEMEADERDRKREKEEL--EEIRQRLLAEGHPDPDAELQRMEQEAERR 572

Query: 425 R---------GKPSEQLTPTRAEKLKDAGLQAPKPVQHP-LHPVPTPHHTVPSLISNHG- 473
           R          +  E+    + EK ++   +  +P Q P L P   P  + PS+ S  G 
Sbjct: 573 RQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGN 632

Query: 474 -IFSLPSSSAATALLIQRTNEEEKWLARQRR 503
              + P   +   ++I   N  ++    + R
Sbjct: 633 ATPNTPGDESPCGIIIPHENSPDQQQPEEHR 663



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 33/73 (45%), Positives = 52/73 (71%), Gaps = 7/73 (9%)

Query: 331 LQMDEELR----REREREREREREREADR-EREKEREREREKEREQEKEREREKE-RERE 384
           ++M+E+ R    RE  + R+  ++ E ++ ++EKER+   ++ RE+E+ERERE+E RERE
Sbjct: 267 IEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERE 326

Query: 385 LERQREQRAREKE 397
            ER+RE R REKE
Sbjct: 327 RERERE-REREKE 338



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 51/217 (23%), Positives = 87/217 (40%), Gaps = 35/217 (16%)

Query: 743 EERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLT 802
           EERRR  A+E     +  + YD  D+ +   + R  A Q  L+     ++ + ++     
Sbjct: 483 EERRREMAKEAKRLKEFLEDYD--DDRDDPKYYRGSALQKRLR-----DREKEMEADERD 535

Query: 803 TQQQKEELVAQKRRKRRRMLRERSPSPPT-IQSKRQTPSPRLALSTRYSPDEMNNSPNFE 861
            +++KEEL       R+R+L E  P P   +Q   Q    R     +  P+    S   E
Sbjct: 536 RKREKEEL----EEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPE----SEEEE 587

Query: 862 EKKKFLTIFNLTHISAEKRKDKERLVEMLRAMKQKALSAAVADSLTNSPRDSPAVSLSEP 921
           E+K+            EK + +E  +E     +QK         ++++P  S A   + P
Sbjct: 588 EEKQ------------EKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATP 635

Query: 922 ATQQASLDVEKPVGVAASLSDIPKAAEPGKLEQVRPQ 958
            T       E P G+     + P   +P   E+ RP+
Sbjct: 636 NTP----GDESPCGIIIPHENSPDQQQP---EEHRPK 665



 Score = 32.0 bits (71), Expect = 3.7
 Identities = 28/146 (19%), Positives = 66/146 (45%), Gaps = 32/146 (21%)

Query: 1082 QQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFE---------- 1131
            ++E    R+    +E ++D + + EED+ED  +  ++ +RK +  EA ++          
Sbjct: 410  EREREREREREREREREKDKKRDREEDEEDAYERRKL-ERKLREKEAAYQERLKNWEIRE 468

Query: 1132 -----AYQEHIEEQNLERQVLQTQCRRL------------EARHYSLSLTAEQLSHSVAE 1174
                  Y++  E +   R+ +  + +RL            + ++Y  S   ++L     E
Sbjct: 469  RKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKE 528

Query: 1175 LRSQKQKMVSERERLQAELDHLRKCL 1200
            + + ++    +R+R + EL+ +R+ L
Sbjct: 529  MEADER----DRKREKEELEEIRQRL 550


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 99/381 (25%), Positives = 161/381 (42%), Gaps = 61/381 (16%)

Query: 329 ERLQMDEELR---REREREREREREREADREREKEREREREKEREQEKEREREKEREREL 385
           E+    EE+R   RE+ERERE+E E+E ++EREKERE++RE+++E+EKE E+E+E++RE+
Sbjct: 496 EKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREM 555

Query: 386 ERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTP--------TRA 437
           E++R+Q  +EKEL   K  E     + E         +ER K  E++ P           
Sbjct: 556 EKERKQE-KEKELERQKEKEKELQKMKE-QEKECELEKEREKLEEKIEPREPNLEPMVEK 613

Query: 438 EKLKDAGLQAPKPV-------QHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQ- 489
           ++ +++  +  +PV       +      P  H T P   S       P  +  +    Q 
Sbjct: 614 QESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQ------PRPAVLSGYFKQF 667

Query: 490 RTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRP-ESTTRP 548
           + +   ++  +Q +++Q++  +Q Q     Q V  Q      PP P    HRP     +P
Sbjct: 668 QKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPP----HRPLYQPMQP 723

Query: 549 GPNRHEPGGRDP----------PQHFGGPPP---------LISPKPQLHAAPTALWNPVS 589
            P      G DP          P+   G P          +I PKP +        + + 
Sbjct: 724 HPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRR------DQME 777

Query: 590 LMDNTLETRRAESHSLHSHPAAFEPSRQA----AVPLVKVERVFCPEKAEEGPRKREPAP 645
              N+ E+    + S   H  +    R        P  + ++   P+  EE    R  A 
Sbjct: 778 GSPNSSESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAA 837

Query: 646 LDKYQPPPPPPREGGSLEHQP 666
           LD+ Q       E   LE  P
Sbjct: 838 LDQEQITAAYSVEHNQLEAHP 858



 Score = 39.3 bits (90), Expect = 0.023
 Identities = 31/128 (24%), Positives = 58/128 (45%), Gaps = 14/128 (10%)

Query: 8    PKSPSLGMLSTATRTTATVNPLTPSPLNGALVPSGSPATSSALSAQAAPSSSFAAALRKL 67
            P SP   + ++A+ + +     + + +  +  P+ +PA +  L++ + P     A++  L
Sbjct: 1802 PASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTP-----ASVTIL 1856

Query: 68   AKQAEEPRGSSLSSESSPVSSPATNHSSPA-------STPKRVPMGPIIVPPGGHSVPST 120
            A  +     S+L+S S+P  +PA   SSPA       + P   P   + + P   S P+ 
Sbjct: 1857 ASASIPILASALASTSAPTPAPAA--SSPAAPVITAPTIPASAPTASVPLAPASASAPAP 1914

Query: 121  PPVVTIAP 128
             P    AP
Sbjct: 1915 APTPVSAP 1922



 Score = 38.9 bits (89), Expect = 0.030
 Identities = 59/257 (22%), Positives = 91/257 (35%), Gaps = 24/257 (9%)

Query: 2    KGMSHEPKSPSLGMLSTAT-----RTTATVNPLTPSPLNGALVPSGSPATSSALSAQAAP 56
            KG S   K P       AT     +++A+V PL  +PL  +   S   +TS+ L A   P
Sbjct: 1717 KGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTP 1776

Query: 57   SSSFAAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHS 116
              +  +A    +  A     +S    +SP++  + + S  AS P       I       S
Sbjct: 1777 VPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPAS 1836

Query: 117  VPSTPPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQEKAGGPA----- 171
             P+  P++    T     +  S S     S  +S          P P   A  PA     
Sbjct: 1837 APAPTPILASVSTPASVTILASASIPILASALAS-------TSAPTPAPAASSPAAPVIT 1889

Query: 172  ---IPSHLLSTPYPFGLSPSSVVQDSRFP-PLNLQRPVHHVVPPSTVTEDYLRSFRPYHT 227
               IP+   +   P  L+P+S    +  P P++   P     P  T  + +     P  T
Sbjct: 1890 APTIPASAPTASVP--LAPASASAPAPAPTPVSAPNPA-PPAPAQTQAQTHKPVQNPLQT 1946

Query: 228  TDDLRMSSLPPLGLDPA 244
            T        P + L  A
Sbjct: 1947 TSQSSKQPPPSIRLPSA 1963



 Score = 37.4 bits (85), Expect = 0.088
 Identities = 32/130 (24%), Positives = 59/130 (45%), Gaps = 5/130 (3%)

Query: 1070 SSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAV 1129
            SS   PPP+   QQ PP  R+  P +     S+++  ++DE  +            +E  
Sbjct: 403  SSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERA 462

Query: 1130 FEAYQEHIEEQNLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERER- 1188
             +  +E  EE+ +E Q       +L+     L +  +Q   S  E+R ++++   ERE+ 
Sbjct: 463  RKRREE--EERRMEEQRKAACAEKLKRLDEKLGILEKQ--PSPEEIREREREKEREREKE 518

Query: 1189 LQAELDHLRK 1198
            L+ E +  R+
Sbjct: 519  LEKEQEQERE 528



 Score = 34.7 bits (78), Expect = 0.57
 Identities = 27/119 (22%), Positives = 53/119 (44%), Gaps = 4/119 (3%)

Query: 1073 RAPPPQHNGQQEPPTARKGPPTQELDRDSE-EEEEEDDEDGEDEEEVPKRKWQGIEAVFE 1131
            + P P+   ++E    R+     E +++ E E+E E D + + E+E    K Q  +   E
Sbjct: 497  KQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREME 556

Query: 1132 AYQEHIEEQNLERQ---VLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERE 1187
              ++  +E+ LERQ     + Q  + + +   L    E+L   +       + MV ++E
Sbjct: 557  KERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQE 615



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 55/245 (22%), Positives = 91/245 (37%), Gaps = 41/245 (16%)

Query: 461  PHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQRRLR------QEKEDRQSQ 514
            PHHT  +  +    F  P     +A   +R +  E   +R+R +       Q+ ++++S+
Sbjct: 884  PHHTDAN--NQSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSE 941

Query: 515  VSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRP--GPNRHEPGGRDPPQHFGGPPPLIS 572
             S    +V  + +D   P    E + + E   R   GP + E   +   +   GP P  +
Sbjct: 942  PSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGP-KPEKVYKSKSETRWGPRPSSN 1000

Query: 573  PKPQLHAAPTALWNPVSL-----MDNTLETRRAESHSLHSHPAAFEPSRQAAVPLVKVER 627
             + +++  P     P+       M    E R+ +                      K E+
Sbjct: 1001 RREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGE-------------------KAEK 1041

Query: 628  VFCPEKAEEGPRKREPAPLDKYQPPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILG 687
            V   EK    P K E   L    PPPPPP +  +      +P P    AE   ST+T   
Sbjct: 1042 V--TEKVVVKPEKTEKKDL----PPPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTETATL 1095

Query: 688  QQRAS 692
             Q+ S
Sbjct: 1096 AQKPS 1100



 Score = 31.6 bits (70), Expect = 4.8
 Identities = 38/140 (27%), Positives = 56/140 (40%), Gaps = 25/140 (17%)

Query: 711 PYRPPVPRAPDP------AYIYDEFLQQRRRLVSKLDL----------EERRRREAQEKG 754
           P R  VP  P P          DE  +QRRR  S++            EE RR E Q K 
Sbjct: 420 PDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKA 479

Query: 755 YYYDLDDSYDES--------DEEEVRAHLRCVAEQPPLKLDTSSEK-LEFLQLFGLTTQQ 805
              +     DE           EE+R   R    +   +L+   E+  E  +      QQ
Sbjct: 480 ACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQ 539

Query: 806 QKEELVAQKRRKRRRMLRER 825
           +KE+ + +++ K+R M +ER
Sbjct: 540 EKEKELEKEQEKQREMEKER 559



 Score = 31.2 bits (69), Expect = 6.3
 Identities = 23/120 (19%), Positives = 52/120 (43%), Gaps = 1/120 (0%)

Query: 1036 QKALQKHKGSVAVLSAEQNHKVDTSVHYNIPELQSSSRAPPPQHNGQQEPPTARKGPPTQ 1095
            ++  +K +     L  EQ  + +     +    Q   +    +   Q+E    RK    +
Sbjct: 506  EREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEK 565

Query: 1096 ELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQNLERQVLQTQCRRLE 1155
            EL+R  E+E+E      +++E   +++ + +E   E  + ++E   +E+Q  +  C + E
Sbjct: 566  ELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPM-VEKQESENSCNKEE 624



 Score = 30.8 bits (68), Expect = 8.2
 Identities = 34/140 (24%), Positives = 55/140 (39%), Gaps = 9/140 (6%)

Query: 325  GLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERE 384
            G   E++   +   R   R     RE   DR   +    ++   R+ ++ERE+ KE+E E
Sbjct: 978  GPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGE 1037

Query: 385  -LERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKDA 443
              E+  E+   + E    K L P   P      ++  +     +P  +  P+      + 
Sbjct: 1038 KAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPS-----TET 1092

Query: 444  GLQAPKPVQ---HPLHPVPT 460
               A KP Q    PL PV T
Sbjct: 1093 ATLAQKPSQDTEKPLEPVST 1112


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 90.1 bits (222), Expect = 1e-17
 Identities = 75/219 (34%), Positives = 109/219 (49%), Gaps = 22/219 (10%)

Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKE-REREK 379
           E+   L  ER + + E  RE+ER+RER+R+R+ DRERE+ERER+REKERE+E+E RERE+
Sbjct: 702 EKERELERERAR-EREREREKERDRERDRDRDHDRERERERERDREKEREREREERERER 760

Query: 380 ERERELERQREQ-----RAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTP 434
           ERERE ER+RE+     R R+KE    +  E       +    R    E+R         
Sbjct: 761 ERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDER 820

Query: 435 TRAEKLKDAGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEE 494
              ++ ++ G  +P P Q P        H+  S   N G       +    LL Q    +
Sbjct: 821 KSKKRYRNEG--SPSPRQSPKR---RREHSPDSDAYNSG----DDKNEKHRLLSQVVRPQ 871

Query: 495 E------KWLARQRRLRQEKEDRQSQVSEFRQQVLEQHL 527
           E        L   R+ R ++EDR+ +  E  ++  EQ L
Sbjct: 872 ESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQEL 910



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 43/74 (58%), Positives = 57/74 (77%), Gaps = 10/74 (13%)

Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEK----------EREREKERER 383
           + E  RERER+RERE+ERE +RER +EREREREKER++E+          ERERE++RE+
Sbjct: 688 ERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREK 747

Query: 384 ELERQREQRAREKE 397
           E ER+RE+R RE+E
Sbjct: 748 EREREREERERERE 761



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 38/66 (57%), Positives = 55/66 (83%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQ 391
           + + +  RE+ERE ERER RE +REREKER+RER+++R+ ++ERERE+ER+RE ER+RE+
Sbjct: 694 ERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERER 753

Query: 392 RAREKE 397
             RE+E
Sbjct: 754 EERERE 759



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 43/73 (58%), Positives = 57/73 (78%), Gaps = 3/73 (4%)

Query: 328 AERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELER 387
           A     + E  RERERERERER+RE ++ERE ERER RE+ERE+EKER+RE++R+R+ +R
Sbjct: 676 ARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDR 735

Query: 388 QRE---QRAREKE 397
           +RE   +R REKE
Sbjct: 736 ERERERERDREKE 748



 Score = 84.7 bits (208), Expect = 5e-16
 Identities = 44/71 (61%), Positives = 53/71 (74%), Gaps = 7/71 (9%)

Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQ-- 391
           D    R RER+RERER+RE +RERE+ER+REREKERE E+ER RE+ERERE ER RE+  
Sbjct: 670 DRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDR 729

Query: 392 -----RAREKE 397
                R RE+E
Sbjct: 730 DRDHDRERERE 740



 Score = 83.6 bits (205), Expect = 1e-15
 Identities = 46/90 (51%), Positives = 61/90 (67%), Gaps = 2/90 (2%)

Query: 309 ELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADRERE-KEREREREK 367
           EL          ER      ER   D +  RERERERER+RE+E +RERE +ERERERE+
Sbjct: 706 ELERERAREREREREKERDRER-DRDRDHDRERERERERDREKEREREREERERERERER 764

Query: 368 EREQEKEREREKERERELERQREQRAREKE 397
           ERE+E+ERERE+ RER+ ER+R++   +K+
Sbjct: 765 ERERERERERERARERDKERERQRDWEDKD 794



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 39/79 (49%), Positives = 54/79 (68%), Gaps = 3/79 (3%)

Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERERE 378
           H  R   L  +  + +  + R  +R  ER RER+ +RER++ERERERE+ER++E+E+ERE
Sbjct: 647 HQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERE 706

Query: 379 KERERELERQREQRAREKE 397
            ERER  ER+RE   REKE
Sbjct: 707 LERERARERERE---REKE 722



 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 34/76 (44%), Positives = 54/76 (71%), Gaps = 2/76 (2%)

Query: 318  LHSERMSGLSAERLQMDEELRRERERERERE--REREADREREKEREREREKEREQEKER 375
            +HS   S  S +RLQ  +    +RERERER   R+RE DR+ +K+  R R+++R +E+ER
Sbjct: 1286 VHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERER 1345

Query: 376  EREKERERELERQREQ 391
            ERE+++ R+L+R+RE+
Sbjct: 1346 ERERDKRRDLDRERER 1361



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 41/108 (37%), Positives = 60/108 (55%), Gaps = 7/108 (6%)

Query: 305 RYPP-----ELSHSSLAALHSERMSGLSAERLQMDEELRRERERERERER-EREADRERE 358
           RYP      +   SS    H ER    + ER Q      R + R  E ER ER  +R  +
Sbjct: 607 RYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVD 666

Query: 359 KEREREREKEREQEKEREREKERERELERQRE-QRAREKELLAAKALE 405
           +  +R  E+ RE+++ERER++ERERE ER+R+ +R +E+EL   +A E
Sbjct: 667 RVDDRRDERARERDRERERDRERERERERERDREREKERELERERARE 714



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 23/64 (35%), Positives = 42/64 (65%)

Query: 334  DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393
            D++  R R+R+R RERERE +R++ ++ +RERE+      ER+R+++R+R  E  + +  
Sbjct: 1328 DKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESV 1387

Query: 394  REKE 397
            +  E
Sbjct: 1388 KRCE 1391



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 25/60 (41%), Positives = 39/60 (65%)

Query: 339  REREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKEL 398
            R+R+R RERERERE D+ R+ +RERER      E++R+R+++R  E  +    +  E +L
Sbjct: 1335 RDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKL 1394



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 34/104 (32%), Positives = 53/104 (50%), Gaps = 25/104 (24%)

Query: 319  HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERE-- 376
            HS R S   ++R Q+         R+R +ER+R        E +RERE+ER   ++RE  
Sbjct: 1273 HSSRRSSPESDR-QVHSRSGSFDSRDRLQERDRY-------EHDRERERERRDTRQREWD 1324

Query: 377  ------------REKERERELERQREQRA---REKELLAAKALE 405
                        R++ RERE ER+R++R    RE+E L + ++E
Sbjct: 1325 RDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVE 1368



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 10/119 (8%)

Query: 276 LRSPFYPIPTPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDE 335
           LR    P P+     P    +   H S +R      H        ER S     R +  E
Sbjct: 367 LRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDH--------ERTSQSHDRRHERRE 418

Query: 336 ELRREREREREREREREADREREKEREREREKEREQEKERE--REKERERELERQREQR 392
           + R +R+RE++   ERE ++++   R+   ++E    ++R   R+    REL   R+ R
Sbjct: 419 DTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMR 477



 Score = 37.4 bits (85), Expect = 0.088
 Identities = 105/514 (20%), Positives = 184/514 (35%), Gaps = 75/514 (14%)

Query: 338 RRERERE----REREREREADREREKEREREREKEREQEKEREREKERERE---LERQRE 390
           RR  ER     RER + +  D + E ++    E      KE  R + RE+E   + ++R 
Sbjct: 75  RRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERT 134

Query: 391 QRAREKELLAAKALEPS--------FLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKD 442
             + E+ +      + S        ++    L   R     E  K  EQ    + E++  
Sbjct: 135 PESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMK-LEQENMEKREEIII 193

Query: 443 AGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQR 502
               +P+ V+  L P P+   +  S        S P SS+A+    + +      L +QR
Sbjct: 194 KKEVSPEVVRSKLSPSPSLRKSSKSPKRK----SSPKSSSASKKDRKTSAVSSPLLDQQR 249

Query: 503 RLRQEKEDRQSQVSEFRQQVLEQHLDMGRP-PVPAEAEHRPESTTRPGPNRHEPGGRD-- 559
             +  +  ++   +      + + + +G+      + + R E  TR G +R    GRD  
Sbjct: 250 NSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDR----GRDFE 305

Query: 560 PPQHFGGPPPLISPKPQLHAAPTALWNPVSLMDNTLETRRAESHSLHSHPAAFEPS-RQA 618
             +     P   SP  Q H       +P+S   ++  ++   S   HS      PS R+ 
Sbjct: 306 RQREKRDKPRSTSPAGQHH-------SPISSRHHSSSSQSGSSIQRHS------PSPRRK 352

Query: 619 AVPLVKVERVFCP---EKAEEGPRKREPAPLDKYQPP--PPPPREGGSLEHQPFLPGPGP 673
             P    +R   P     A   P     +P  K  PP    P RE G  +H+        
Sbjct: 353 RTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHE-------- 404

Query: 674 FLAELEKSTQTILGQQRASLPQAATFGELSGPLKPGSPYRPPVPRAPDPAYIYDEFLQQR 733
                    +T     R    +  T G+           R     + +      +    R
Sbjct: 405 ---------RTSQSHDRRHERREDTRGK-----------RDREKDSREEREYEQDQSSSR 444

Query: 734 RRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAE-QPPLKLDTSSEK 792
                +   + R RR+A++     +L DS D  D  E+R + R   E + P    ++ + 
Sbjct: 445 DHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDA 504

Query: 793 LEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERS 826
            ++    G  T ++++    + R   R  LRE S
Sbjct: 505 HDYRDREGRDTHRKEDTYPEESRSYGRNHLREES 538



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 3/56 (5%)

Query: 338  RREREREREREREREADREREKEREREREKEREQEKER---EREKERERELERQRE 390
            R++      R    E+DR+          ++R QE++R   +RE+ERER   RQRE
Sbjct: 1267 RQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQRE 1322



 Score = 31.2 bits (69), Expect = 6.3
 Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 25/114 (21%)

Query: 308 PELSHSSLAALHSERMSGLSAERLQMDEELRRERERERERERERE-ADREREKERERERE 366
           PEL           ++   S+     D    R    ER+R  ER+  D+ R+   ER R 
Sbjct: 568 PELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFER-RH 626

Query: 367 KEREQEKEREREKE---------RERELER--------------QREQRAREKE 397
            ER++   RER++          R  ELER              +R++RARE++
Sbjct: 627 GERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERD 680



 Score = 31.2 bits (69), Expect = 6.3
 Identities = 30/126 (23%), Positives = 55/126 (43%), Gaps = 10/126 (7%)

Query: 326  LSAERLQMDEELR-RERERERER-EREREADREREKEREREREKEREQEKEREREKERER 383
            LS   L  D + R +E +R+ ER E  R  + +  KE+    +K+REQ +  E  + R +
Sbjct: 876  LSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQ 935

Query: 384  EL-------ERQREQRAREKELLAAKALEPSFLPVAELH-GLRGHATEERGKPSEQLTPT 435
            ++       +R+   RA ++    AK  +       E   G+     E   +  +  +P 
Sbjct: 936  DIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPK 995

Query: 436  RAEKLK 441
            + +K K
Sbjct: 996  KGQKKK 1001



 Score = 31.2 bits (69), Expect = 6.3
 Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 5/66 (7%)

Query: 23   TATVNPLTPSPLNGALVPSGSPATSSALSAQAAPSSSFAAALRKLAKQAEEPRGSSLSSE 82
            TAT    TPSPL+  L P    AT++A +  A  +++ AAA    +  A      ++S+ 
Sbjct: 1086 TATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSA-----ITISTS 1140

Query: 83   SSPVSS 88
            ++P ++
Sbjct: 1141 ATPTNT 1146


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 42/69 (60%), Positives = 56/69 (81%), Gaps = 1/69 (1%)

Query: 330 RLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQR 389
           R + D E  R+RER+RERERERE +R+RE+ERERERE+ER++E ER+REKERER+ +RQ 
Sbjct: 290 RTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQT 349

Query: 390 E-QRAREKE 397
           E  R R ++
Sbjct: 350 EMDRERNRQ 358



 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 38/79 (48%), Positives = 58/79 (73%), Gaps = 1/79 (1%)

Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERERE 378
           HSER      ER + + E  R+R+ +RER+R+R+ +REREK+ ERER  ERE E+++ERE
Sbjct: 205 HSERGRERERER-ETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE 263

Query: 379 KERERELERQREQRAREKE 397
           +ER+R+ +R R Q+ RE++
Sbjct: 264 RERDRDRDRDRRQKERERQ 282



 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 40/77 (51%), Positives = 58/77 (75%), Gaps = 1/77 (1%)

Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380
           ER      +R Q + E + +R+R+R  ER+RE +R+RE++RERERE+ER +++ERERE+E
Sbjct: 265 ERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERE 324

Query: 381 RERELERQREQRAREKE 397
           RERE +R+ E R REKE
Sbjct: 325 RERERQRETE-RDREKE 340



 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 35/65 (53%), Positives = 51/65 (78%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQ 391
           Q D + +R  ER+RE ER+RE  RERE+ERER R++ERE+E+ERERE++RE E +R++E+
Sbjct: 282 QTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKER 341

Query: 392 RAREK 396
             + K
Sbjct: 342 ERKRK 346



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 51/119 (42%), Positives = 69/119 (57%), Gaps = 15/119 (12%)

Query: 321 ERMSGLSAERLQMDEELRRERERERER-----EREREADR------EREKEREREREKER 369
           ER S    ER   D+E  RER+R+R+R     ERER+ DR      ER++E ER+RE++R
Sbjct: 249 ERASERETER---DKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQR 305

Query: 370 EQEKEREREKERERELERQRE-QRAREKELLAAKALEPSFLPVAELHGLRGHATEERGK 427
           E+E+ERER ++RERE ER+RE +R RE E    K  E       E+   R   T   G+
Sbjct: 306 ERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGR 364



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 40/90 (44%), Positives = 56/90 (62%), Gaps = 24/90 (26%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQ-------------------- 371
           Q + E  RER R+RERERERE +RER++E ER+REKERE+                    
Sbjct: 304 QRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG 363

Query: 372 ----EKEREREKERERELERQREQRAREKE 397
               E+ERERE+ER+R+  R+RE+R R+++
Sbjct: 364 RRQAERERERERERDRQSAREREERERDRD 393



 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 45/118 (38%), Positives = 67/118 (56%), Gaps = 7/118 (5%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEK------EREREKEREREL 385
           Q D +  RER+R+ E+ERER+ DRER+++ ER R+KERE+EK      ERER++E+E + 
Sbjct: 142 QTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKT 201

Query: 386 ERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATE-ERGKPSEQLTPTRAEKLKD 442
           E +  +R RE+E       E       +    R   TE ER K +E+   +  E  +D
Sbjct: 202 EDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERD 259



 Score = 74.3 bits (181), Expect = 6e-13
 Identities = 42/94 (44%), Positives = 59/94 (62%), Gaps = 17/94 (18%)

Query: 329 ERLQMDEELRREREREREREREREADREREKERERE--------REKEREQEKEREREKE 380
           E+ Q + E  R+RER RE++R R+ DR RE++R+RE        RE++R++EKER R+KE
Sbjct: 67  EKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKE 126

Query: 381 RERELERQRE---------QRAREKELLAAKALE 405
           RERE ER+ E         QR RE++  A K  E
Sbjct: 127 RERETEREGERGRDRQTDGQRERERQRDAEKERE 160



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 36/71 (50%), Positives = 51/71 (71%), Gaps = 5/71 (7%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQ--- 388
           +   E  RERER R+RERERE +RERE++RE ER++E+E+E++R+R+ E +RE  RQ   
Sbjct: 302 ERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGR 361

Query: 389 --REQRAREKE 397
             R Q  RE+E
Sbjct: 362 EGRRQAERERE 372



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 34/78 (43%), Positives = 57/78 (73%), Gaps = 1/78 (1%)

Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380
           +R      ER +  E+ + ERE +R+RER RE DR R+++R RER+++RE+E+ER+ ++E
Sbjct: 53  DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112

Query: 381 RERELERQR-EQRAREKE 397
           R+R+ E++R  Q+ RE+E
Sbjct: 113 RDRQREKERNRQKERERE 130



 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 38/83 (45%), Positives = 60/83 (72%), Gaps = 7/83 (8%)

Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERE---- 376
           ER +    ER +  +   R+R+R+ ERERE++A+RER  ERE ER+KERE+E++R+    
Sbjct: 215 ERETETETERKRQTDR-ERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD 273

Query: 377 -REKERERELERQREQRA-REKE 397
            R+KERER+ +R+R++R  R++E
Sbjct: 274 RRQKERERQTDRKRQRRTERDRE 296



 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 35/67 (52%), Positives = 53/67 (79%), Gaps = 2/67 (2%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQRE- 390
           Q + E   ERE ER++ERERE DR+R+++R R++E+ER+ +++R+R  ER+RE ER+RE 
Sbjct: 245 QAERERASERETERDKERERERDRDRDRDR-RQKERERQTDRKRQRRTERDRETERKRER 303

Query: 391 QRAREKE 397
           QR RE+E
Sbjct: 304 QRERERE 310



 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 43/88 (48%), Positives = 61/88 (69%), Gaps = 11/88 (12%)

Query: 320 SERMSGLSAERLQMDE-ELRREREREREREREREADREREKERERER--------EKERE 370
           +ER     AER +  E E  R++ERERER+R+R+ DR R+KERER+         E++RE
Sbjct: 238 TEREREKQAERERASERETERDKERERERDRDRDRDR-RQKERERQTDRKRQRRTERDRE 296

Query: 371 QEKEREREKERERELERQRE-QRAREKE 397
            E++RER++ERERE ER R+ +R RE+E
Sbjct: 297 TERKRERQRERERERERNRKRERERERE 324



 Score = 70.9 bits (172), Expect = 7e-12
 Identities = 34/79 (43%), Positives = 56/79 (70%), Gaps = 1/79 (1%)

Query: 320 SERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREK 379
           +ER      ER +     R ERER+R+R+R++E +R+ EK+R+ +RE E+++E+E++RE 
Sbjct: 367 AERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRES 426

Query: 380 ERERELERQRE-QRAREKE 397
           ER RE  R+RE Q+ RE++
Sbjct: 427 ERGRERGREREKQKGRERD 445



 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 50/144 (34%), Positives = 73/144 (50%), Gaps = 28/144 (19%)

Query: 319 HSERMSGLSAER-LQMDEELRREREREREREREREAD----------------REREKER 361
           H ER      ER  Q D E  R+RE+ER R++ERE +                RERE++R
Sbjct: 94  HRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR 153

Query: 362 EREREKEREQEKEREREKERERELERQRE---QRAREKELLAAKALEPSFLPVAELHGLR 418
           + E+E+ER+ ++ER+R+ ER R+ ER+RE   Q  RE+E    K  +       + H  R
Sbjct: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK-----TEDRHSER 208

Query: 419 GHATEERGKPSEQLTPTRAEKLKD 442
           G    ER +  E  T T  ++  D
Sbjct: 209 G---RERERERETETETERKRQTD 229



 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 42/99 (42%), Positives = 56/99 (56%), Gaps = 23/99 (23%)

Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKERERER--------------- 365
           ER      ER + + +  RERERERERER+RE +R+REKERER+R               
Sbjct: 302 ERQRERERER-ERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTG 360

Query: 366 -------EKEREQEKEREREKERERELERQREQRAREKE 397
                  E+ERE+E+ER+R+  RERE   +   R R+KE
Sbjct: 361 REGRRQAERERERERERDRQSAREREERERDRDRDRQKE 399



 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 41/77 (53%), Positives = 53/77 (68%), Gaps = 10/77 (12%)

Query: 330 RLQMDEELRRERERERE-----REREREADREREKEREREREKER----EQEKEREREKE 380
           R Q + E  RERER+R+      ERER+ DR+R+KERER+ EK+R    E EK+REREK+
Sbjct: 364 RRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKD 423

Query: 381 RERELERQREQRAREKE 397
           RE E  R+R  R REK+
Sbjct: 424 RESERGRER-GREREKQ 439



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 37/91 (40%), Positives = 61/91 (67%), Gaps = 1/91 (1%)

Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380
           ER    + ER + + +  R+R++ERER+ E++ D +RE E++REREK+RE E+ RER +E
Sbjct: 376 ERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRE 435

Query: 381 RERELERQREQRAREKELLAAKALEPSFLPV 411
           RE++  R+R+ R R+ +  A +  + S L V
Sbjct: 436 REKQKGRERD-RERQTDRQAGRQRKRSTLYV 465



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 40/83 (48%), Positives = 53/83 (63%), Gaps = 14/83 (16%)

Query: 329 ERLQMDEELRRERERERERERE------------READREREKEREREREKEREQ--EKE 374
           E+    E+   ER RERERERE            RE DR+R+ ERERE++ ERE+  E+E
Sbjct: 196 EKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERE 255

Query: 375 REREKERERELERQREQRAREKE 397
            ER+KERERE +R R++  R+KE
Sbjct: 256 TERDKERERERDRDRDRDRRQKE 278



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 66/236 (27%), Positives = 100/236 (42%), Gaps = 54/236 (22%)

Query: 325 GLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERE 384
           G   ER +  E  RR  +R+ ERE +R+ +R REK+R R+R++ R  E++R+REKERER+
Sbjct: 51  GDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHR--ERQRDREKERERQ 108

Query: 385 LERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKDAG 444
            +R+R+ R REKE    K  E       E  G RG   +  G+          E+ +DA 
Sbjct: 109 TDRERD-RQREKERNRQKERERE----TEREGERGRDRQTDGQ-------RERERQRDAE 156

Query: 445 LQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQR-R 503
            +  +                                       QR  E  +   R+R +
Sbjct: 157 KERERQTDRER---------------------------------QRQTERNRQKEREREK 183

Query: 504 LRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRD 559
            RQE+ +R+ Q  E   +  ++H + GR     E E   E+ T     R     RD
Sbjct: 184 NRQERRERERQ-REKENKTEDRHSERGR-----ERERERETETETERKRQTDRERD 233



 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 42/104 (40%), Positives = 60/104 (57%), Gaps = 19/104 (18%)

Query: 321 ERMSGLSAER-LQMDEELRREREREREREREREADREREKEREREREKE----------- 368
           ER      ER  Q D E +R+ ER R++ERERE +R+  +ERER+REKE           
Sbjct: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERG 209

Query: 369 --REQEKEREREKERERELERQRE-----QRAREKELLAAKALE 405
             RE+E+E E E ER+R+ +R+R+     +R REK+    +A E
Sbjct: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 38/89 (42%), Positives = 62/89 (69%), Gaps = 5/89 (5%)

Query: 320 SERMSGLSAERLQMDEELRRERERERERE---REREADREREKEREREREKEREQEKERE 376
           +ER      ER +  +E RRERER+RE+E    +R ++R RE+ERERE E E E++++ +
Sbjct: 171 TERNRQKEREREKNRQE-RRERERQREKENKTEDRHSERGRERERERETETETERKRQTD 229

Query: 377 REKERERELERQREQRAREKELLAAKALE 405
           RE++R+R+ ER+RE++A E+E  + +  E
Sbjct: 230 RERDRQRKTEREREKQA-ERERASERETE 257


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 178/852 (20%), Positives = 305/852 (35%), Gaps = 172/852 (20%)

Query: 336  ELRREREREREREREREADREREKEREREREKEREQEKEREREKER--ERELERQREQRA 393
            EL++E  ++R+ E+E+ A  +++ E + +R+KE ++    +RE+ R   R   R    R 
Sbjct: 125  ELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRR 184

Query: 394  REKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKDAGLQ------- 446
            R   +   +    S  P             E+ + + +L P  + K+K+  +Q       
Sbjct: 185  RSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPEL-PEPSVKVKEPSVQEATSTSD 243

Query: 447  ---APKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQRR 503
                PKP      P+P P    P   S                  ++  E+EK   R R 
Sbjct: 244  ILKVPKP-----EPIPEPKEPSPEKNS------------------KKEKEKEKTRPRSRS 280

Query: 504  LRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQH 563
             R +   R    S    +   +H    R   P     RP    RP P R     R PP+ 
Sbjct: 281  -RSKSRSRTRSRSPSHTRPRRRHRSRSRSYSP---RRRPSPRRRPSPRR-----RTPPRR 331

Query: 564  FGGPPPLISPKPQLHAAPTALWNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAAVPLV 623
               PPP   P+ +   +P             +  RR  S SL    ++   SR  + P  
Sbjct: 332  M--PPP---PRHRRSRSP-------------VRRRRRSSASLSGSSSSSSSSRSRSPPKK 373

Query: 624  KVERVFCPEKAEEGPRKREPAPLDKYQPPP---PPPREGGSLEHQPFLPGPGPFLAELEK 680
              +R   P +           P  +++P P   PPP+   S       P P       ++
Sbjct: 374  PPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHS-------PTP-------QQ 419

Query: 681  STQTILGQQRASLPQAATFGELS---GPLKPGSPYRPPVPRAPDPAYIYDEFLQQRRRLV 737
            S +T   + R S+    T G+++   G  K  SP   P PR  +   + +    +  ++ 
Sbjct: 420  SNRT--RKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVE---LSESEEDKGGKMA 474

Query: 738  SKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHL--------------RCVAEQP- 782
            +   +++RR+   Q +    D   S    DE   R+H+              R  +  P 
Sbjct: 475  AADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR 534

Query: 783  PLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRML---RERSPSPPTIQSKRQTP 839
              + +TS             T++++    A   R+RR      R R+PSPP    +R++P
Sbjct: 535  KRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPP---PRRRSP 591

Query: 840  SPRL---ALSTRYSPD--------------EMNNSPNFEEKKKFLTIFNLTHISAEKRKD 882
            SPR     +  RYSP               +   SP+   K++      ++H    K++ 
Sbjct: 592  SPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRR------VSHSPPPKQRS 645

Query: 883  K---ERLVEMLRAMKQKALSAAVADSLTNSP----RDSPAVSLSEPATQQASLDV----- 930
                +R    L +  +K  S + +     SP    R SP+     P T  +   V     
Sbjct: 646  SPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGAS 705

Query: 931  ------EKPVGVAASLSDIPKAAEPGKLEQV---RPQELSRVQELAPASGEKARLSEAPG 981
                  + P      +  + +  EP K+++     PQ + RV      SG     S  P 
Sbjct: 706  SSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSG-----SPEPA 760

Query: 982  GKKSLSMLHYIRGAAPK---DIPVPLSHSTNGKSKPWEPFVA-EEFAHQFHESVLQSTQK 1037
             KK  +    ++  +P       VP+  + +    P  P  + +E   +  +       K
Sbjct: 761  AKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHK 820

Query: 1038 ALQKHKGSVAVLSAEQNHKVDTSVHYNIPELQSSSRAPPPQHNGQQEPPTARKGPPTQEL 1097
              +KHK         + HK + +V        + +          QE P A    P  + 
Sbjct: 821  KDKKHK-------KHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVA---APEPKK 870

Query: 1098 DRDSEEEEEEDD 1109
            + +SE E+  DD
Sbjct: 871  ETESEAEDNLDD 882



 Score = 37.7 bits (86), Expect = 0.067
 Identities = 44/188 (23%), Positives = 63/188 (33%), Gaps = 25/188 (13%)

Query: 31  PSPLNGALVPSGSPATSSALSAQAAPSSSFAAALRKLAKQAEEPRGSSLSSESSPVSSPA 90
           P P      PS  P    + S      SS     R  +  ++  +GSS S  +    SP 
Sbjct: 618 PPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQ 677

Query: 91  TNHSSPASTPKRVPMGPIIVPPGGHSV-----------PSTPPVVTIAPTKTVNGVWRSE 139
            N     S   R P      PP                PST P+  ++ T     + ++ 
Sbjct: 678 PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAA 737

Query: 140 S------RQDAGSRSSSGGRERLIVEPPLPQEKA--------GGPAIPSHLLSTPYPFGL 185
           S      R+ + SRS SG  E    +PP P              PA+P     +P P   
Sbjct: 738 SPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPS 797

Query: 186 SPSSVVQD 193
            P +  Q+
Sbjct: 798 PPRNSDQE 805



 Score = 37.4 bits (85), Expect = 0.088
 Identities = 83/402 (20%), Positives = 139/402 (34%), Gaps = 73/402 (18%)

Query: 55  APSSSFAAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTP----KRVPMGPIIV 110
           +PS S + + RK  K+   PRG    S S P   P     SP+  P    +R P      
Sbjct: 524 SPSRSASPSPRKRQKETS-PRGRRRRSPSPP---PTRRRRSPSPAPPPRRRRTP-----T 574

Query: 111 PPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQEKAGGP 170
           PP     PS PP       +  +   R  S       S S   +R    PP P ++   P
Sbjct: 575 PPPRRRTPSPPP-------RRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASP 627

Query: 171 AIP----------------------SHLLSTPYPFGLSPSSVVQDSRFPPLNLQRPVHHV 208
           + P                      S  LS+ +  G SPS   +++R P  N +R     
Sbjct: 628 SPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPN-KRHSPSP 686

Query: 209 VPPSTVTEDYLRSFRPYHTTDDLRMSSLPPLGLDPATAAAYYHPSYL--APHPFPHPAFR 266
            P +  T       R   ++   R  S  P        +    P  +  A  P P    R
Sbjct: 687 RPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR 746

Query: 267 MDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLHLSGVRYPPEL--------SHSSLAAL 318
           +  S  +S    P          PP  PS +        + P +        + S     
Sbjct: 747 VSSSRSVSGSPEP------AAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPR 800

Query: 319 HSERMSGLSAERLQMDEELRRERERERERERERE-------------ADREREKERERER 365
           +S++  G   ++ + D++ +++++ ++ ++ ++E             A          + 
Sbjct: 801 NSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQE 860

Query: 366 EKEREQEKEREREKERERELERQREQRAREKELLAAKALEPS 407
           E     E ++E E E E  L+   E+  REK L + +  + S
Sbjct: 861 EPVAAPEPKKETESEAEDNLD-DLEKHLREKALRSMRKAQVS 901


>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 202

 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 35/73 (47%), Positives = 54/73 (73%)

Query: 320 SERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREK 379
           +ER      ER    E   R R+R+R RER+R+ DRE+E+ER++ER+++R++E+E ERE 
Sbjct: 17  TERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERET 76

Query: 380 ERERELERQREQR 392
           ER+RE +RQRE++
Sbjct: 77  ERQRERQRQRERK 89



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 37/79 (46%), Positives = 58/79 (73%), Gaps = 13/79 (16%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKE------------REQEKEREREK 379
           + + E  R+RER+R+RER+R+ DRER+K+R+RER++E            RE++K+ ERE+
Sbjct: 71  ETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERER 130

Query: 380 ERERELERQRE-QRAREKE 397
           +RERE +RQRE +R R++E
Sbjct: 131 DRERERQRQRERERQRQRE 149



 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 41/83 (49%), Positives = 61/83 (73%), Gaps = 6/83 (7%)

Query: 320 SERMSGLSAERLQMDEELR---REREREREREREREADREREKERE--REREKEREQEKE 374
           +ER +    ER +  E  R   RER+++R+RER+RE DR RE+ R+  RER+K+ E+E++
Sbjct: 72  TERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERD 131

Query: 375 REREKERERELERQREQRAREKE 397
           RERE++R+RE ERQR QR R++E
Sbjct: 132 RERERQRQRERERQR-QRERKRE 153



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 32/66 (48%), Positives = 54/66 (81%), Gaps = 1/66 (1%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQRE- 390
           Q D E  RER++ER+R+R+RE + ERE ER+RER+++RE++++ +RE++++R+ ER+RE 
Sbjct: 49  QTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRET 108

Query: 391 QRAREK 396
            R RE+
Sbjct: 109 DRNRER 114



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 30/61 (49%), Positives = 50/61 (81%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQ 391
           + D +  RE+ERER++ER+R+  RERE ERE ER++ER++++ER+R+ +RER+ +R RE+
Sbjct: 45  ERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRER 104

Query: 392 R 392
           +
Sbjct: 105 K 105



 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 33/84 (39%), Positives = 61/84 (72%), Gaps = 6/84 (7%)

Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERERE 378
           H ER      E+ + + +  R+R+R+RERE ERE +R+RE++R+RER+++ ++E++++R+
Sbjct: 43  HRERDRQTDREK-ERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRD 101

Query: 379 KERERELERQREQ-----RAREKE 397
           +ER+RE +R RE+     R R+K+
Sbjct: 102 RERKRETDRNRERNRKGGRERDKQ 125



 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 39/75 (52%), Positives = 55/75 (73%), Gaps = 12/75 (16%)

Query: 335 EELRRERERERERE-------REREADREREKEREREREKEREQEKEREREKEREREL-- 385
           +E  RER+R+RERE       R R+ DR RE++R+ +REKERE++KER+R+++RERE   
Sbjct: 15  KETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETER 74

Query: 386 --ERQRE-QRAREKE 397
             ERQRE QR RE++
Sbjct: 75  ETERQRERQRQRERK 89



 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 31/66 (46%), Positives = 56/66 (84%), Gaps = 1/66 (1%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQ 391
           + D++  RER+RERER+R+RE +R+R++ER+RE ++ER++  ERE E+++ER+ ER++E+
Sbjct: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE-ERKKERKKERKKER 179

Query: 392 RAREKE 397
           + ++KE
Sbjct: 180 KEKKKE 185



 Score = 71.2 bits (173), Expect = 5e-12
 Identities = 30/64 (46%), Positives = 51/64 (79%)

Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393
           + E  R+  RER+++ ERE DRERE++R+RERE++R++E++RE ++ER+R  ER+  ++ 
Sbjct: 111 NRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKE 170

Query: 394 REKE 397
           R+KE
Sbjct: 171 RKKE 174



 Score = 70.9 bits (172), Expect = 7e-12
 Identities = 32/70 (45%), Positives = 53/70 (75%), Gaps = 6/70 (8%)

Query: 334 DEELRRERERERER------EREREADREREKEREREREKEREQEKEREREKERERELER 387
           D E +RE +R RER      ER+++ +RER++ERER+R++ERE++++RER++E +RE +R
Sbjct: 101 DRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQR 160

Query: 388 QREQRAREKE 397
             E+  R+KE
Sbjct: 161 WAEREERKKE 170



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 36/80 (45%), Positives = 55/80 (68%), Gaps = 4/80 (5%)

Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380
           ER      ER   D +  R+RE +R RER R+  RER+K+ ERER++ERE++++RERE++
Sbjct: 87  ERKRQTDRER-DKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQ 145

Query: 381 RERELERQRE---QRAREKE 397
           R+RE +R+ +   QR  E+E
Sbjct: 146 RQRERKRETDRERQRWAERE 165



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 33/74 (44%), Positives = 54/74 (72%), Gaps = 8/74 (10%)

Query: 332 QMDEELRREREREREREREREADRE---REKEREREREKEREQEKEREREKERERELERQ 388
           + D     ERER+R+RERE + +RE   R+++R RER+++ ++EKERER+KER+R+ +R+
Sbjct: 10  ETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRE 69

Query: 389 RE-----QRAREKE 397
           RE     +R RE++
Sbjct: 70  RETERETERQRERQ 83



 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 28/66 (42%), Positives = 51/66 (77%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQ 391
           + D    R R+  RER+++ E +R+RE+ER+R+RE+ER++++ER+RE +RER+   +RE+
Sbjct: 107 ETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREE 166

Query: 392 RAREKE 397
           R +E++
Sbjct: 167 RKKERK 172



 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 30/79 (37%), Positives = 59/79 (74%), Gaps = 1/79 (1%)

Query: 329 ERLQMDEELRREREREREREREREADREREKEREREREKEREQ-EKEREREKERERELER 387
           ++ + + +  RER+R+RERER+R+ +R+RE +RER+R  ERE+ +KER++E+++ER+ ++
Sbjct: 124 KQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKK 183

Query: 388 QREQRAREKELLAAKALEP 406
           + E+R  +K+    + + P
Sbjct: 184 KEEKRREDKKRKWGEGISP 202



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 34/72 (47%), Positives = 51/72 (70%), Gaps = 8/72 (11%)

Query: 333 MDEELRREREREREREREREADREREKE-------REREREKEREQEKEREREKEREREL 385
           M+ +  R+RE +R +E ERE DR+RE+E       R R+R++ RE++++ +REKERER+ 
Sbjct: 1   MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60

Query: 386 ERQREQRAREKE 397
           ER R QR RE+E
Sbjct: 61  ERDR-QRQRERE 71



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 29/67 (43%), Positives = 54/67 (80%), Gaps = 5/67 (7%)

Query: 336 ELRREREREREREREREADREREKEREREREKEREQEKER-----EREKERERELERQRE 390
           E  ++ ERER+RERER+  RERE++R+RER++E ++E++R     ER+KER++E +++R+
Sbjct: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERK 180

Query: 391 QRAREKE 397
           ++ +E++
Sbjct: 181 EKKKEEK 187



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 22/62 (35%), Positives = 37/62 (59%), Gaps = 8/62 (12%)

Query: 321 ERMSGLSAERLQMDEELRRERERER-------EREREREADREREKEREREREKEREQEK 373
           ER      ER Q   E +RE +RER       ER++ER+ +R++E++ +++ EK RE +K
Sbjct: 135 ERQRQRERER-QRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKK 193

Query: 374 ER 375
            +
Sbjct: 194 RK 195


>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
          Length = 953

 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 143/661 (21%), Positives = 237/661 (35%), Gaps = 142/661 (21%)

Query: 330 RLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQR 389
           R+Q  E       RERERERERE +R+RE+ERERER++ERE+ ++RERE+ERE E +++R
Sbjct: 389 RVQYTETEPYHNYRERERERERE-NRQRERERERERDRERER-RQREREREREHERDKER 446

Query: 390 EQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKDAGLQAPK 449
           ++R  E E   AK  E            R H   +R K          E+ K+ G   P+
Sbjct: 447 QRRKEEWERERAKRDEKD----------RQHRDRDREK----------EREKEKGKPKPR 486

Query: 450 PVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQRRLRQEKE 509
             Q P      P                   +A T   ++R +E   W    RR +  K+
Sbjct: 487 SPQPPSRQAEPP----------------KKEAATTGPQVKRADE---WKDPWRRSKSPKK 527

Query: 510 DRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQHFGGPPP 569
                VS                P  A    +  +++    N      R       G   
Sbjct: 528 KLGVSVS----------------PSRARRRRKTSASSASASNSSRSSSRSSSYSGSG--- 568

Query: 570 LISPKPQLHAAPTALWNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAAVPLVKVERVF 629
             S + +  ++  + ++  S   ++    R+ S S  S P+   PS              
Sbjct: 569 --SSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPS---PS-------------- 609

Query: 630 CPEKAEEGPRKREPAPLDKYQPPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQ 689
                   P    P+   K +P PPP + G   E     P P P   +  K+T       
Sbjct: 610 ------PTPSPHRPSIRTKGEPAPPPGKAG---EKSVKKPAPPPAPPQATKTT------- 653

Query: 690 RASLPQAATFGELSGPLKPGSPYRPPVPR------APDPAYIYDEFLQQRRRLVSKLDLE 743
            A +P+    G+     +   P R P  R             Y     + R L       
Sbjct: 654 -APVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSS 712

Query: 744 ERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTT 803
                 +    +  D +D Y      ++ + +   + + P    T  EK           
Sbjct: 713 VSSATSSSSSAHSVDSEDMY-----ADLASPVSSASSRSPAPAQTRKEK----------G 757

Query: 804 QQQKEELVAQKRRKRRRMLR-ERSPSPPTIQSKRQTPS-PRLALSTRYSPDEMNNSPNFE 861
           + +KE+ V +++RKR    +  +S  PP      Q PS P+ A      P +        
Sbjct: 758 KSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQA-----PPGQPQQGTFVA 812

Query: 862 EKKKFLTIFNLTHISAEKRK----DKERL---------VEMLRAMKQKALSAAVADSLTN 908
            K+  LT+ N       +++    DK+R              R  + +     +      
Sbjct: 813 HKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPE 872

Query: 909 SPRDSPAVSLSEPATQQASLDVEKPVGVAASLSDIP-KAAEPG--KLEQVRPQELSRVQE 965
             R   + + + PA ++  L  +     ++ ++ +P KA++PG    +  +   LSR +E
Sbjct: 873 RQRGQNSKAPAAPADRKRQLSPQSK--SSSKVTSVPGKASDPGAASTKSGKASTLSRREE 930

Query: 966 L 966
           L
Sbjct: 931 L 931



 Score = 74.3 bits (181), Expect = 6e-13
 Identities = 41/71 (57%), Positives = 51/71 (71%), Gaps = 2/71 (2%)

Query: 329 ERLQMDEELRRERERERERERERE-ADREREKEREREREKEREQEKER-EREKERERELE 386
           ER +  E  +RERERERER+RERE   RERE+ERE ER+KER++ KE  ERE+ +  E +
Sbjct: 405 ERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKD 464

Query: 387 RQREQRAREKE 397
           RQ   R REKE
Sbjct: 465 RQHRDRDREKE 475



 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 34/60 (56%), Positives = 43/60 (71%), Gaps = 4/60 (6%)

Query: 329 ERLQMDEELRREREREREREREREADREREKER-EREREKERE---QEKEREREKERERE 384
           ER +  E  RR+RERERERE ER+ +R+R KE  ERER K  E   Q ++R+REKERE+E
Sbjct: 420 ERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKE 479



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 86/392 (21%), Positives = 140/392 (35%), Gaps = 49/392 (12%)

Query: 321 ERMSGLSAERLQMDEELRREREREREREREREA-DREREKERERERE-KEREQEKERERE 378
           ER      ER Q + E  RE ER++ER+R +E  +RER K  E++R+ ++R++EKERE+E
Sbjct: 420 ERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKE 479

Query: 379 KERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAE 438
           K + +    Q   R  E     A    P      E       +   + K    ++P+RA 
Sbjct: 480 KGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRAR 539

Query: 439 KLKDAGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWL 498
           + +     +            +   +  S  S  G     S S++ +    R++    + 
Sbjct: 540 RRRKTSASSASASN------SSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFS 593

Query: 499 ARQRRLR--QEKEDRQSQVSEFRQQVLEQHLDMGRP----------PVPAEAEHRPESTT 546
             + R R            S  R  +  +      P          P P  A  +   TT
Sbjct: 594 GSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTT 653

Query: 547 RPGPNRHEPGGRDPPQHFGGPPPLISPKPQLHAAPTALWNPVSLMDNTLETR-------- 598
            P P   +PG  DP +      P  +P  +   + +   +  S   ++  +R        
Sbjct: 654 APVPEPTKPG--DPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVS 711

Query: 599 -----RAESHSLHS-----------HPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKRE 642
                 + S S HS            P +   SR  A    + E+     K E+G ++ +
Sbjct: 712 SVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEK--GKSKKEDGVKEEK 769

Query: 643 PAPLDKYQPP-PPPPREGGSLEHQPFLPGPGP 673
                  QPP    P  GG    QP  P   P
Sbjct: 770 RKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAP 801



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 29/64 (45%), Positives = 46/64 (71%), Gaps = 2/64 (3%)

Query: 329 ERLQMDEELRREREREREREREREADREREKERER-EREKEREQEKEREREKERERELER 387
           ER +  +  R  R+RERERERE E D+ER++ +E  ERE+ +  EK+R+  ++R+RE ER
Sbjct: 418 ERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQ-HRDRDREKER 476

Query: 388 QREQ 391
           ++E+
Sbjct: 477 EKEK 480



 Score = 31.2 bits (69), Expect = 6.3
 Identities = 78/390 (20%), Positives = 141/390 (36%), Gaps = 43/390 (11%)

Query: 731  QQRRRLVSKLDLEERRRREA--QEKGYYYDLDDSYDESDEEEVRAHLRCVAEQPPLKLDT 788
            ++ R    + D E +RR+E   +E+    + D  + + D E+ R   +   +  P     
Sbjct: 433  EREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEK--GKPKPRSPQP 490

Query: 789  SSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRER------SPSPPTIQSKRQTPSPR 842
             S + E  +    TT  Q +     K   RR    ++      SPS    + K    S  
Sbjct: 491  PSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSAS 550

Query: 843  LALSTRYSPDEMNNSPNFEEKKKFLTIFNLTHISAEKRKDKERLVEMLRAMKQKALSAAV 902
             + S+R S    + S +   + +  +    ++ S   R  +       R+ + ++ S++ 
Sbjct: 551  ASNSSRSSSRSSSYSGSGSSRSRSRSS---SYSSYSSRSSRHSSFSGSRS-RSRSFSSSP 606

Query: 903  ADSLTNSPRDSPAVSLSEPAT---QQASLDVEKPVGVAA------SLSDIPKAAEPGKLE 953
            + S T SP      +  EPA    +     V+KP    A      + + +P+  +PG   
Sbjct: 607  SPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPR 666

Query: 954  QVRPQELS------RVQELAPASGEKARLSEAPGGKKSLSMLHYIRGAAPKDIPVPLSHS 1007
            + R +E        R       SG  +  S +    +SLS+      ++   +    S S
Sbjct: 667  EARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSV------SSVSSVSSATSSS 720

Query: 1008 TNGKSKPWEPFVAEEFAHQFHESVLQSTQKALQKHKGSVAVLSA--EQNHKVDTSVHYNI 1065
            ++  S   E   A+  +     S         +K KG         E+  K D+S     
Sbjct: 721  SSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQ--- 777

Query: 1066 PELQSSSRAPPPQHNGQQEPPTARKGPPTQ 1095
                  S  PP      Q+P T ++ PP Q
Sbjct: 778  ---PPKSAKPPAGGKSSQQPSTPQQAPPGQ 804


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 77.4 bits (189), Expect = 8e-14
 Identities = 33/67 (49%), Positives = 57/67 (85%), Gaps = 1/67 (1%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQRE- 390
           + D E  RERE+ERE+E+ER  +++R+KERE++REK++E+++EREREKE E++ ++++E 
Sbjct: 392 EKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEK 451

Query: 391 QRAREKE 397
           ++ +EKE
Sbjct: 452 EQDKEKE 458



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 37/82 (45%), Positives = 62/82 (75%), Gaps = 4/82 (4%)

Query: 319 HSERMSGLSAERLQMDEELR---REREREREREREREADREREKEREREREKEREQEKER 375
           HS      + E+++  E ++   RE+ERERE+ERE+E +R + K+R++EREK+RE++KE+
Sbjct: 372 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 431

Query: 376 EREKERERELERQREQRAREKE 397
           +RE+ERE+E E+ R+ + +EKE
Sbjct: 432 DREREREKEHEKDRD-KEKEKE 452



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 27/63 (42%), Positives = 53/63 (84%)

Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393
           D +  RE++RE+++E++RE +RE+E E++R++EKE+EQ+KE+EREK+R +E++ +R++  
Sbjct: 416 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 475

Query: 394 REK 396
           + +
Sbjct: 476 KSR 478



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 45/137 (32%), Positives = 75/137 (54%), Gaps = 14/137 (10%)

Query: 308 PELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKERERE--- 364
           P    S        R    S ++ +   E  +E+ER +E++RE+E +RE+E+E+E+E   
Sbjct: 354 PHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK 413

Query: 365 ---REKEREQEKEREREKERERELERQREQ-RAREKELLAAKALEPSFLPVAELHGLRGH 420
              R+KERE+++E+++EK+RERE E++ E+ R +EKE    K  E       E+      
Sbjct: 414 NKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEI------ 467

Query: 421 ATEERGKPSEQLTPTRA 437
             E+R K  +  TP R+
Sbjct: 468 -DEKRKKDKKSRTPPRS 483



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 31/80 (38%), Positives = 48/80 (60%), Gaps = 2/80 (2%)

Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERERE 378
           H+   S     R       +R + RER + R R   R++ K+  RE+ KE+E+ KE++RE
Sbjct: 338 HNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT-REKIKEKERVKEKDRE 396

Query: 379 KERERELERQRE-QRAREKE 397
           KERERE ER++E +R + K+
Sbjct: 397 KEREREKEREKEKERGKNKD 416



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 30/89 (33%), Positives = 56/89 (62%), Gaps = 3/89 (3%)

Query: 311 SHSSLAALHSERMSGLSAERLQM-DEELRREREREREREREREADREREKEREREREKER 369
           SH+   +   +R    S  + +    E R+ R R   R++ ++  RE+ KE+ER +EK+R
Sbjct: 337 SHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT-REKIKEKERVKEKDR 395

Query: 370 EQEKEREREKERERELERQREQ-RAREKE 397
           E+E+ERE+E+E+E+E  + +++ + REK+
Sbjct: 396 EKEREREKEREKEKERGKNKDRDKEREKD 424



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 3/80 (3%)

Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKERERERE-KEREQEKERER 377
           H  R    S  R Q D    +   ++R + RER   R R   R++ ++ +E+ +EKER +
Sbjct: 333 HRSRSHNRSRSR-QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVK 391

Query: 378 EKERERELERQREQRAREKE 397
           EK+RE+E ER++E R +EKE
Sbjct: 392 EKDREKEREREKE-REKEKE 410



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 27/89 (30%), Positives = 39/89 (43%)

Query: 308 PELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREK 367
           PE   S+       R    S  R       RR+R + + R R     R R+K+R R +  
Sbjct: 295 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 354

Query: 368 EREQEKEREREKERERELERQREQRAREK 396
            +++ K RER K R R   R + +  REK
Sbjct: 355 HKKRSKSRERRKSRSRSHSRDKRKDTREK 383



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 9/85 (10%)

Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERE-- 376
           HS R    S  R +      R R R+++R R +   ++R K RER + + R   +++   
Sbjct: 323 HSRRKRSQSKHRSRSHN---RSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKD 379

Query: 377 -REK--ERERELERQRE-QRAREKE 397
            REK  E+ER  E+ RE +R REKE
Sbjct: 380 TREKIKEKERVKEKDREKEREREKE 404



 Score = 38.5 bits (88), Expect = 0.039
 Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 20/84 (23%)

Query: 334 DEELRREREREREREREREADREREKE--------------------REREREKEREQEK 373
           ++E  +++E+ERE++R +E D +R+K+                    RER R + R   +
Sbjct: 448 EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSR 507

Query: 374 EREREKERERELERQREQRAREKE 397
                K  +R+  R    R+R K+
Sbjct: 508 SPRTSKTIKRKSSRSPSPRSRNKK 531



 Score = 37.7 bits (86), Expect = 0.067
 Identities = 18/59 (30%), Positives = 27/59 (45%)

Query: 339 REREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKE 397
           R   RER R R R + R     +  +R+  R        +K+++RE ER      RE+E
Sbjct: 491 RSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERE 549



 Score = 34.7 bits (78), Expect = 0.57
 Identities = 17/63 (26%), Positives = 29/63 (46%)

Query: 341 REREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKELLA 400
           RER R R R         K  +R+  +        +++K+RE+E +   E+R RE+    
Sbjct: 495 RERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSM 554

Query: 401 AKA 403
            K+
Sbjct: 555 RKS 557



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 23/101 (22%), Positives = 46/101 (45%), Gaps = 8/101 (7%)

Query: 305 RYPPELSHSSLAALHSER-----MSGLSAERLQMDEELRREREREREREREREADREREK 359
           R PP   ++S  +  S R      S  S+   +  + ++R+  R        + D++REK
Sbjct: 478 RTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK 537

Query: 360 EREREREKEREQEKEREREKERERELERQREQRA---REKE 397
           ER+   E+   +     R+   +R+ + + E+ +   +EKE
Sbjct: 538 ERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKE 578



 Score = 32.3 bits (72), Expect = 2.8
 Identities = 21/100 (21%), Positives = 43/100 (43%), Gaps = 1/100 (1%)

Query: 314 SLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEK 373
           S ++  S R S     +       R   +++++RE+ER+   ER +ERER     +    
Sbjct: 502 SRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER-RERERSTSMRKSSND 560

Query: 374 EREREKERERELERQREQRAREKELLAAKALEPSFLPVAE 413
              +EK  +     + ++  +E +   +K ++    P  E
Sbjct: 561 RDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 600



 Score = 31.2 bits (69), Expect = 6.3
 Identities = 19/79 (24%), Positives = 40/79 (50%), Gaps = 10/79 (12%)

Query: 330 RLQMDEELRRERERE---REREREREA-------DREREKEREREREKEREQEKEREREK 379
           R +  ++ +RE+ER+     RERER         DR+ +++ E+     +E+E  +E + 
Sbjct: 526 RSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDS 585

Query: 380 ERERELERQREQRAREKEL 398
              +E++ +   R  E ++
Sbjct: 586 SVSKEVDDKDAPRTEENKI 604


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 77.4 bits (189), Expect = 8e-14
 Identities = 33/67 (49%), Positives = 57/67 (85%), Gaps = 1/67 (1%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQRE- 390
           + D E  RERE+ERE+E+ER  +++R+KERE++REK++E+++EREREKE E++ ++++E 
Sbjct: 276 EKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEK 335

Query: 391 QRAREKE 397
           ++ +EKE
Sbjct: 336 EQDKEKE 342



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 37/82 (45%), Positives = 62/82 (75%), Gaps = 4/82 (4%)

Query: 319 HSERMSGLSAERLQMDEELR---REREREREREREREADREREKEREREREKEREQEKER 375
           HS      + E+++  E ++   RE+ERERE+ERE+E +R + K+R++EREK+RE++KE+
Sbjct: 256 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 315

Query: 376 EREKERERELERQREQRAREKE 397
           +RE+ERE+E E+ R+ + +EKE
Sbjct: 316 DREREREKEHEKDRD-KEKEKE 336



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 27/63 (42%), Positives = 53/63 (84%)

Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393
           D +  RE++RE+++E++RE +RE+E E++R++EKE+EQ+KE+EREK+R +E++ +R++  
Sbjct: 300 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 359

Query: 394 REK 396
           + +
Sbjct: 360 KSR 362



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 45/137 (32%), Positives = 75/137 (54%), Gaps = 14/137 (10%)

Query: 308 PELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKERERE--- 364
           P    S        R    S ++ +   E  +E+ER +E++RE+E +RE+E+E+E+E   
Sbjct: 238 PHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK 297

Query: 365 ---REKEREQEKEREREKERERELERQREQ-RAREKELLAAKALEPSFLPVAELHGLRGH 420
              R+KERE+++E+++EK+RERE E++ E+ R +EKE    K  E       E+      
Sbjct: 298 NKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEI------ 351

Query: 421 ATEERGKPSEQLTPTRA 437
             E+R K  +  TP R+
Sbjct: 352 -DEKRKKDKKSRTPPRS 367



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 31/80 (38%), Positives = 48/80 (60%), Gaps = 2/80 (2%)

Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERERE 378
           H+   S     R       +R + RER + R R   R++ K+  RE+ KE+E+ KE++RE
Sbjct: 222 HNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT-REKIKEKERVKEKDRE 280

Query: 379 KERERELERQRE-QRAREKE 397
           KERERE ER++E +R + K+
Sbjct: 281 KEREREKEREKEKERGKNKD 300



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 30/89 (33%), Positives = 56/89 (62%), Gaps = 3/89 (3%)

Query: 311 SHSSLAALHSERMSGLSAERLQM-DEELRREREREREREREREADREREKEREREREKER 369
           SH+   +   +R    S  + +    E R+ R R   R++ ++  RE+ KE+ER +EK+R
Sbjct: 221 SHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT-REKIKEKERVKEKDR 279

Query: 370 EQEKEREREKERERELERQREQ-RAREKE 397
           E+E+ERE+E+E+E+E  + +++ + REK+
Sbjct: 280 EKEREREKEREKEKERGKNKDRDKEREKD 308



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 3/80 (3%)

Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKERERERE-KEREQEKERER 377
           H  R    S  R Q D    +   ++R + RER   R R   R++ ++ +E+ +EKER +
Sbjct: 217 HRSRSHNRSRSR-QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVK 275

Query: 378 EKERERELERQREQRAREKE 397
           EK+RE+E ER++E R +EKE
Sbjct: 276 EKDREKEREREKE-REKEKE 294



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 27/89 (30%), Positives = 39/89 (43%)

Query: 308 PELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREK 367
           PE   S+       R    S  R       RR+R + + R R     R R+K+R R +  
Sbjct: 179 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 238

Query: 368 EREQEKEREREKERERELERQREQRAREK 396
            +++ K RER K R R   R + +  REK
Sbjct: 239 HKKRSKSRERRKSRSRSHSRDKRKDTREK 267



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 9/85 (10%)

Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERE-- 376
           HS R    S  R +      R R R+++R R +   ++R K RER + + R   +++   
Sbjct: 207 HSRRKRSQSKHRSRSHN---RSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKD 263

Query: 377 -REK--ERERELERQRE-QRAREKE 397
            REK  E+ER  E+ RE +R REKE
Sbjct: 264 TREKIKEKERVKEKDREKEREREKE 288



 Score = 38.5 bits (88), Expect = 0.039
 Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 20/84 (23%)

Query: 334 DEELRREREREREREREREADREREKE--------------------REREREKEREQEK 373
           ++E  +++E+ERE++R +E D +R+K+                    RER R + R   +
Sbjct: 332 EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSR 391

Query: 374 EREREKERERELERQREQRAREKE 397
                K  +R+  R    R+R K+
Sbjct: 392 SPRTSKTIKRKSSRSPSPRSRNKK 415



 Score = 37.7 bits (86), Expect = 0.067
 Identities = 18/59 (30%), Positives = 27/59 (45%)

Query: 339 REREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKE 397
           R   RER R R R + R     +  +R+  R        +K+++RE ER      RE+E
Sbjct: 375 RSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERE 433



 Score = 34.7 bits (78), Expect = 0.57
 Identities = 17/63 (26%), Positives = 29/63 (46%)

Query: 341 REREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKELLA 400
           RER R R R         K  +R+  +        +++K+RE+E +   E+R RE+    
Sbjct: 379 RERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSM 438

Query: 401 AKA 403
            K+
Sbjct: 439 RKS 441



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 23/101 (22%), Positives = 46/101 (45%), Gaps = 8/101 (7%)

Query: 305 RYPPELSHSSLAALHSER-----MSGLSAERLQMDEELRREREREREREREREADREREK 359
           R PP   ++S  +  S R      S  S+   +  + ++R+  R        + D++REK
Sbjct: 362 RTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK 421

Query: 360 EREREREKEREQEKEREREKERERELERQREQRA---REKE 397
           ER+   E+   +     R+   +R+ + + E+ +   +EKE
Sbjct: 422 ERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKE 462



 Score = 32.3 bits (72), Expect = 2.8
 Identities = 21/100 (21%), Positives = 43/100 (43%), Gaps = 1/100 (1%)

Query: 314 SLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEK 373
           S ++  S R S     +       R   +++++RE+ER+   ER +ERER     +    
Sbjct: 386 SRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER-RERERSTSMRKSSND 444

Query: 374 EREREKERERELERQREQRAREKELLAAKALEPSFLPVAE 413
              +EK  +     + ++  +E +   +K ++    P  E
Sbjct: 445 RDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 484



 Score = 31.2 bits (69), Expect = 6.3
 Identities = 19/79 (24%), Positives = 40/79 (50%), Gaps = 10/79 (12%)

Query: 330 RLQMDEELRRERERE---REREREREA-------DREREKEREREREKEREQEKEREREK 379
           R +  ++ +RE+ER+     RERER         DR+ +++ E+     +E+E  +E + 
Sbjct: 410 RSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDS 469

Query: 380 ERERELERQREQRAREKEL 398
              +E++ +   R  E ++
Sbjct: 470 SVSKEVDDKDAPRTEENKI 488


>gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens]
          Length = 520

 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 76/240 (31%), Positives = 114/240 (47%), Gaps = 45/240 (18%)

Query: 252 PSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPP-LHPSAMHLHLSGV--RYPP 308
           P++L P PF  P   +  +  L  +  P +P P PG+ PP L P+    H SG   R   
Sbjct: 292 PTHLPPPPFLPPPPTVSTAPPL--IPPPGFP-PPPGAPPPSLIPTIESGHSSGYDSRSAR 348

Query: 309 ELSHSSLAALH----SERMSGLSAERLQMDEELRREREREREREREREADREREKERERE 364
              + ++A  H    +     L     Q D   RRE++R+RER+R+RE DR+R++ERER 
Sbjct: 349 AFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERT 408

Query: 365 REKEREQ-----------EKEREREKE------------RERELERQREQRAREKELLAA 401
           RE+ERE+           ++ER R +E            RE+E ER RE+R REKE    
Sbjct: 409 RERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKE-ERHRERRHREKEETRH 467

Query: 402 KALEPSFLPVAELHGLRGHATEE--RGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVP 459
           K+        +  +  R H +EE    +  +     R+++ K+AG + P P Q      P
Sbjct: 468 KS--------SRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSE-PAPEQESTEATP 518


>gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens]
          Length = 594

 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 76/240 (31%), Positives = 114/240 (47%), Gaps = 45/240 (18%)

Query: 252 PSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPP-LHPSAMHLHLSGV--RYPP 308
           P++L P PF  P   +  +  L  +  P +P P PG+ PP L P+    H SG   R   
Sbjct: 366 PTHLPPPPFLPPPPTVSTAPPL--IPPPGFP-PPPGAPPPSLIPTIESGHSSGYDSRSAR 422

Query: 309 ELSHSSLAALH----SERMSGLSAERLQMDEELRREREREREREREREADREREKERERE 364
              + ++A  H    +     L     Q D   RRE++R+RER+R+RE DR+R++ERER 
Sbjct: 423 AFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERT 482

Query: 365 REKEREQ-----------EKEREREKE------------RERELERQREQRAREKELLAA 401
           RE+ERE+           ++ER R +E            RE+E ER RE+R REKE    
Sbjct: 483 RERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKE-ERHRERRHREKEETRH 541

Query: 402 KALEPSFLPVAELHGLRGHATEE--RGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVP 459
           K+        +  +  R H +EE    +  +     R+++ K+AG + P P Q      P
Sbjct: 542 KS--------SRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSE-PAPEQESTEATP 592


>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 290

 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 41/73 (56%), Positives = 54/73 (73%), Gaps = 9/73 (12%)

Query: 334 DEELRREREREREREREREADREREKEREREREKER--------EQEKEREREKEREREL 385
           + E ++ RERER+R RERE DR+REKERER+ EK+R        E+E++REREK++ERE 
Sbjct: 126 EREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERET 185

Query: 386 ERQRE-QRAREKE 397
           ER R+ QR  EKE
Sbjct: 186 ERDRDRQRDTEKE 198



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 35/62 (56%), Positives = 52/62 (83%), Gaps = 1/62 (1%)

Query: 336 ELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRARE 395
           E+ R+RERE+++ RERE DR RE+ER+R+REKERE++ E++R+ +RE E ER+R+ R RE
Sbjct: 120 EIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERD-RERE 178

Query: 396 KE 397
           K+
Sbjct: 179 KQ 180



 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 57/156 (36%), Positives = 78/156 (50%), Gaps = 40/156 (25%)

Query: 282 PIPTPGSLPPLHPSAMHLHLS------GVRYPPELSHSSLAALHSERMSGLSA------- 328
           P+ T   L P    A HLH S       V  P + S   L +  S R  GL         
Sbjct: 15  PVKTSPLLVPSLTYAPHLHSSLGTLWVEVTIPLDFSRGRLGSQESPRSWGLGQAHKDADG 74

Query: 329 -----ERLQMDEELRRERERERERERER-------------------EADREREKE--RE 362
                ER ++ E+  +ER+R+R+R+RER                   E DREREK+  RE
Sbjct: 75  DDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134

Query: 363 REREKEREQEKEREREKERERELERQRE-QRAREKE 397
           RER++ RE+E++R+REKERER+ E+ R+ QR  E E
Sbjct: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETE 170



 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 36/81 (44%), Positives = 58/81 (71%), Gaps = 4/81 (4%)

Query: 321 ERMSGLSAERLQMDEELR---REREREREREREREADREREKEREREREKEREQEKERER 377
           E+  G   ER +  E  R   RE+ERER+ E++R+  RE E ERER+RE+E+++E+E ER
Sbjct: 128 EKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETER 187

Query: 378 EKERERELERQRE-QRAREKE 397
           +++R+R+ E++RE Q  RE++
Sbjct: 188 DRDRQRDTEKERERQTDRERD 208



 Score = 71.2 bits (173), Expect = 5e-12
 Identities = 37/69 (53%), Positives = 53/69 (76%), Gaps = 3/69 (4%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKER--EREKERERELERQR 389
           Q + E  RERE+++ RERER+  RERE++R+RE+E+ER+ EK+R  +RE E ERE +R+R
Sbjct: 118 QTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRER 177

Query: 390 E-QRAREKE 397
           E Q+ RE E
Sbjct: 178 EKQKERETE 186



 Score = 71.2 bits (173), Expect = 5e-12
 Identities = 29/58 (50%), Positives = 50/58 (86%)

Query: 340 EREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKE 397
           ER+RE +RE ERE DR RE++R+R+R KER++E++R+ E+++ER+ ER++E++ ++KE
Sbjct: 216 ERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKE 273



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 30/75 (40%), Positives = 54/75 (72%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQ 391
           +   E  RE ERE +R RER+ DR+R KER+RER+++ E++KER++E+++ER+ +++ E+
Sbjct: 216 ERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEK 275

Query: 392 RAREKELLAAKALEP 406
           R  +K+    + + P
Sbjct: 276 RREDKKRKWGEGISP 290



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 31/63 (49%), Positives = 50/63 (79%), Gaps = 1/63 (1%)

Query: 336 ELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQRE-QRAR 394
           E   ERER+RERE+++E + ER+++R+R+ EKERE++ +RER+++R+ + ERQRE  R  
Sbjct: 166 ETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREG 225

Query: 395 EKE 397
           E+E
Sbjct: 226 ERE 228



 Score = 67.4 bits (163), Expect = 8e-11
 Identities = 34/80 (42%), Positives = 54/80 (67%), Gaps = 7/80 (8%)

Query: 321 ERMSGLSAERLQMDEELRRERERERER------EREREADREREKEREREREKEREQEKE 374
           ER  G   ER   D E  RER+ E++R      E ERE DREREK++ERE E++R+++++
Sbjct: 136 ERDRGRERER-DRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRD 194

Query: 375 REREKERERELERQREQRAR 394
            E+E+ER+ + ER R+++ +
Sbjct: 195 TEKERERQTDRERDRQRKTQ 214



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 29/69 (42%), Positives = 51/69 (73%), Gaps = 3/69 (4%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQRE- 390
           + + E  R+R+R+ E+ERER+ DRER+++R+ + E++RE ++E ERE +R RE +R R+ 
Sbjct: 182 ERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDR 241

Query: 391 --QRAREKE 397
             +R RE++
Sbjct: 242 GKERDRERD 250



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 27/66 (40%), Positives = 52/66 (78%), Gaps = 1/66 (1%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQ 391
           + D E  +++ERE ER+R+R+ D E+E+ER+ +RE++R+++ + ER++E +RE ER+ ++
Sbjct: 172 ERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDR 231

Query: 392 RAREKE 397
           R RE++
Sbjct: 232 R-RERQ 236



 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 28/67 (41%), Positives = 50/67 (74%), Gaps = 1/67 (1%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQ 391
           Q + E  R+R+R+R+ E+ERE   +RE++R+R+ + ER++E +RE E+E +R  ERQR++
Sbjct: 180 QKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR 239

Query: 392 -RAREKE 397
            R +E++
Sbjct: 240 DRGKERD 246



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 27/67 (40%), Positives = 52/67 (77%), Gaps = 1/67 (1%)

Query: 330 RLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERE-LERQ 388
           + Q + +   +RE ERE +R RE  R+R++ +ER+RE++R++E+++ER+KER++E  E++
Sbjct: 212 KTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKK 271

Query: 389 REQRARE 395
           +E++ RE
Sbjct: 272 KEEKRRE 278



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 30/72 (41%), Positives = 52/72 (72%), Gaps = 7/72 (9%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQ------EKEREREKEREREL 385
           + + +  RE+++ERE ER+R+  R+ EKERER+ ++ER++      E++RE ++E ERE 
Sbjct: 170 ERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERET 229

Query: 386 ERQRE-QRAREK 396
           +R+RE QR R++
Sbjct: 230 DRRRERQRDRDR 241



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 21/52 (40%), Positives = 39/52 (75%)

Query: 330 RLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKER 381
           R +   +  R +ER+RER+R+ E  +ER+KER++ER++++++EK RE +K +
Sbjct: 232 RRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 152/643 (23%), Positives = 216/643 (33%), Gaps = 119/643 (18%)

Query: 22  TTATVNPLTPS----PLNGALVPSGSPATSSALSAQAAPSSSFAAALRKLAKQAEEPRGS 77
           T +   P  PS    PL+G   P      +  L     P   F   L   A Q + P G+
Sbjct: 276 TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFG--LPPQASQGQAPLGT 333

Query: 78  SLS------SESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPSTPPVVTIAPTKT 131
           S +      S   P S  A     P   P+  P+ P          P   P +   PT  
Sbjct: 334 SPAAAYPHTSLQLPASQSALQSQQP---PREQPLPP---------APLAMPHIKPPPTTP 381

Query: 132 VNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQEKAGGPAIPSHLLST-PYPFGLSPSS- 189
           +  +   ++ +     S           PP P  K        H  S  P P  L P S 
Sbjct: 382 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 441

Query: 190 -----------VVQDSRFPPLNLQRP---VHHVVP-PSTVTEDYLRSFRPYHTTDDLRMS 234
                      + Q    PP     P   +H V P P      ++    P  T      +
Sbjct: 442 PLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPST 501

Query: 235 SLPPLG-----LDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSL 289
           S PP G       P + AA    S       P P  ++ +   L     P  P P P S 
Sbjct: 502 STPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEE-ALDDAEEPESPPPPPRSP 560

Query: 290 PPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRRERERERERER 349
            P  P+        V  P   S S+    H +R     A        L   +  ++  E 
Sbjct: 561 SP-EPTV-------VDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEA 612

Query: 350 EREADREREKEREREREKEREQEKEREREKERERELER-------QREQRAREKELLAAK 402
             +A RE E++   ERE+E+E+EKERERE+ERERE ER         E R  + +L    
Sbjct: 613 IEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPG 672

Query: 403 ALEPSFLP----VAELHGLRGHATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPV 458
            + PSF P    +A +    G  T      SE   P          + +P    HP +  
Sbjct: 673 HMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARP---------HVMSPTNRNHPFY-- 721

Query: 459 PTPHHTVPSLISNH--GIFSLPSSSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVS 516
             P +    L++ H  G++++  +                   R+R LR    +R+ +  
Sbjct: 722 -MPLNPTDPLLAYHMPGLYNVDPT------------------IRERELR----EREIRER 758

Query: 517 EFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQ 576
           E R++ L + +  G    P E +        P  N        P +HF     L  P P 
Sbjct: 759 EIRERELRERMKPGFEVKPPELD-----PLHPAAN--------PMEHFARHSALTIP-PT 804

Query: 577 LHAAPTALWNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAA 619
               P A ++P     N LE  R         P    P R AA
Sbjct: 805 AGPHPFASFHPGL---NPLERERLALAGPQLRPEMSYPDRLAA 844



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 95/421 (22%), Positives = 134/421 (31%), Gaps = 85/421 (20%)

Query: 447 APKPVQHPLHPV--PTPHHTVPSLISNHG----IFSLPSSSAATALLIQRTNEEEKWLAR 500
           AP   Q PLH    P PH      +  H      F LP  ++     +  T+    +   
Sbjct: 284 APSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG-TSPAAAYPHT 342

Query: 501 QRRLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDP 560
             +L   +   QSQ     Q   EQ L    PP P    H     T P P    P     
Sbjct: 343 SLQLPASQSALQSQ-----QPPREQPL----PPAPLAMPHIKPPPTTPIPQLPAPQAHKH 393

Query: 561 PQHFGGPPPL-----ISPKPQL--------HAAPTALWNPVSLMDNTLETRRAESHSLHS 607
           P H  GP P      + P P L        H  P+A   P+ LM         +S  L S
Sbjct: 394 PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--------PQSQPLPS 445

Query: 608 HPA---AFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPAPLDKYQPPPPPPREGGSLEH 664
            PA       S+    P          + A + P  +   P     PPP  P    S   
Sbjct: 446 SPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQH--PFVPGGPPPITPPTCPSTST 503

Query: 665 QPFLPGPG--PFLAELEKSTQTILGQQRASLPQAATFGE-LSGPLKPGSPYRPPVPRAPD 721
            P  PG    P  +    S  +I G     LP      E L    +P SP  PP PR+P 
Sbjct: 504 PPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESP--PPPPRSPS 561

Query: 722 PAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQ 781
           P                +  + +     +Q   +Y  LD  Y+     +           
Sbjct: 562 P----------------EPTVVDTPSHASQSARFYKHLDRGYNSCARTD----------- 594

Query: 782 PPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPTIQSKRQTPSP 841
                      L F+ L G    +++EE + + +R+  +  RE        + +R+    
Sbjct: 595 -----------LYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERE 643

Query: 842 R 842
           R
Sbjct: 644 R 644


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 152/643 (23%), Positives = 216/643 (33%), Gaps = 119/643 (18%)

Query: 22   TTATVNPLTPS----PLNGALVPSGSPATSSALSAQAAPSSSFAAALRKLAKQAEEPRGS 77
            T +   P  PS    PL+G   P      +  L     P   F   L   A Q + P G+
Sbjct: 830  TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFG--LPPQASQGQAPLGT 887

Query: 78   SLS------SESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPSTPPVVTIAPTKT 131
            S +      S   P S  A     P   P+  P+ P          P   P +   PT  
Sbjct: 888  SPAAAYPHTSLQLPASQSALQSQQP---PREQPLPP---------APLAMPHIKPPPTTP 935

Query: 132  VNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQEKAGGPAIPSHLLST-PYPFGLSPSS- 189
            +  +   ++ +     S           PP P  K        H  S  P P  L P S 
Sbjct: 936  IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 995

Query: 190  -----------VVQDSRFPPLNLQRP---VHHVVP-PSTVTEDYLRSFRPYHTTDDLRMS 234
                       + Q    PP     P   +H V P P      ++    P  T      +
Sbjct: 996  PLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPST 1055

Query: 235  SLPPLG-----LDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSL 289
            S PP G       P + AA    S       P P  ++ +   L     P  P P P S 
Sbjct: 1056 STPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEE-ALDDAEEPESPPPPPRSP 1114

Query: 290  PPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRRERERERERER 349
             P  P+        V  P   S S+    H +R     A        L   +  ++  E 
Sbjct: 1115 SP-EPTV-------VDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEA 1166

Query: 350  EREADREREKEREREREKEREQEKEREREKERERELER-------QREQRAREKELLAAK 402
              +A RE E++   ERE+E+E+EKERERE+ERERE ER         E R  + +L    
Sbjct: 1167 IEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPG 1226

Query: 403  ALEPSFLP----VAELHGLRGHATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPV 458
             + PSF P    +A +    G  T      SE   P          + +P    HP +  
Sbjct: 1227 HMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARP---------HVMSPTNRNHPFY-- 1275

Query: 459  PTPHHTVPSLISNH--GIFSLPSSSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVS 516
              P +    L++ H  G++++  +                   R+R LR    +R+ +  
Sbjct: 1276 -MPLNPTDPLLAYHMPGLYNVDPT------------------IRERELR----EREIRER 1312

Query: 517  EFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQ 576
            E R++ L + +  G    P E +        P  N        P +HF     L  P P 
Sbjct: 1313 EIRERELRERMKPGFEVKPPELD-----PLHPAAN--------PMEHFARHSALTIP-PT 1358

Query: 577  LHAAPTALWNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAA 619
                P A ++P     N LE  R         P    P R AA
Sbjct: 1359 AGPHPFASFHPGL---NPLERERLALAGPQLRPEMSYPDRLAA 1398



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 95/421 (22%), Positives = 134/421 (31%), Gaps = 85/421 (20%)

Query: 447  APKPVQHPLHPV--PTPHHTVPSLISNHG----IFSLPSSSAATALLIQRTNEEEKWLAR 500
            AP   Q PLH    P PH      +  H      F LP  ++     +  T+    +   
Sbjct: 838  APSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG-TSPAAAYPHT 896

Query: 501  QRRLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDP 560
              +L   +   QSQ     Q   EQ L    PP P    H     T P P    P     
Sbjct: 897  SLQLPASQSALQSQ-----QPPREQPL----PPAPLAMPHIKPPPTTPIPQLPAPQAHKH 947

Query: 561  PQHFGGPPPL-----ISPKPQL--------HAAPTALWNPVSLMDNTLETRRAESHSLHS 607
            P H  GP P      + P P L        H  P+A   P+ LM         +S  L S
Sbjct: 948  PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--------PQSQPLPS 999

Query: 608  HPA---AFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPAPLDKYQPPPPPPREGGSLEH 664
             PA       S+    P          + A + P  +   P     PPP  P    S   
Sbjct: 1000 SPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQH--PFVPGGPPPITPPTCPSTST 1057

Query: 665  QPFLPGPG--PFLAELEKSTQTILGQQRASLPQAATFGE-LSGPLKPGSPYRPPVPRAPD 721
             P  PG    P  +    S  +I G     LP      E L    +P SP  PP PR+P 
Sbjct: 1058 PPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESP--PPPPRSPS 1115

Query: 722  PAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQ 781
            P                +  + +     +Q   +Y  LD  Y+     +           
Sbjct: 1116 P----------------EPTVVDTPSHASQSARFYKHLDRGYNSCARTD----------- 1148

Query: 782  PPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPTIQSKRQTPSP 841
                       L F+ L G    +++EE + + +R+  +  RE        + +R+    
Sbjct: 1149 -----------LYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERE 1197

Query: 842  R 842
            R
Sbjct: 1198 R 1198



 Score = 38.5 bits (88), Expect = 0.039
 Identities = 15/37 (40%), Positives = 31/37 (83%), Gaps = 1/37 (2%)

Query: 353 ADREREKEREREREKEREQEKEREREKERERELERQR 389
           AD++++K++E++R+++R++E+E+ R+K RE E  R R
Sbjct: 3   ADKDKDKDKEKDRDRDRDREREK-RDKARESENSRPR 38



 Score = 37.7 bits (86), Expect = 0.067
 Identities = 14/36 (38%), Positives = 29/36 (80%), Gaps = 1/36 (2%)

Query: 342 EREREREREREADREREKEREREREKEREQEKERER 377
           ++++++++E++ DR+R++ERE+ R+K RE E  R R
Sbjct: 4   DKDKDKDKEKDRDRDRDREREK-RDKARESENSRPR 38



 Score = 37.4 bits (85), Expect = 0.088
 Identities = 14/37 (37%), Positives = 31/37 (83%), Gaps = 1/37 (2%)

Query: 358 EKEREREREKEREQEKEREREK-ERERELERQREQRA 393
           +K++++++EK+R+++++REREK ++ RE E  R +R+
Sbjct: 4   DKDKDKDKEKDRDRDRDREREKRDKARESENSRPRRS 40



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 13/36 (36%), Positives = 29/36 (80%), Gaps = 1/36 (2%)

Query: 348 EREREADREREKEREREREKEREQEKEREREKERER 383
           +++++ D+E++++R+R+RE+E+ ++K RE E  R R
Sbjct: 4   DKDKDKDKEKDRDRDRDREREK-RDKARESENSRPR 38



 Score = 34.7 bits (78), Expect = 0.57
 Identities = 10/30 (33%), Positives = 26/30 (86%)

Query: 368 EREQEKEREREKERERELERQREQRAREKE 397
           +++++K++E++++R+R+ ER++  +ARE E
Sbjct: 4   DKDKDKDKEKDRDRDRDREREKRDKARESE 33



 Score = 34.3 bits (77), Expect = 0.74
 Identities = 18/78 (23%), Positives = 40/78 (51%), Gaps = 14/78 (17%)

Query: 334 DEELRRERERERERERERE-ADREREKERERER-------------EKEREQEKEREREK 379
           D++  +E++R+R+R+RERE  D+ RE E  R R             E +  ++++ +   
Sbjct: 6   DKDKDKEKDRDRDRDREREKRDKARESENSRPRRSCTLEGGAKNYAESDHSEDEDNDNNS 65

Query: 380 ERERELERQREQRAREKE 397
               E  ++ +++  +K+
Sbjct: 66  ATAEESTKKNKKKPPKKK 83


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 152/643 (23%), Positives = 216/643 (33%), Gaps = 119/643 (18%)

Query: 22   TTATVNPLTPS----PLNGALVPSGSPATSSALSAQAAPSSSFAAALRKLAKQAEEPRGS 77
            T +   P  PS    PL+G   P      +  L     P   F   L   A Q + P G+
Sbjct: 830  TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFG--LPPQASQGQAPLGT 887

Query: 78   SLS------SESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPSTPPVVTIAPTKT 131
            S +      S   P S  A     P   P+  P+ P          P   P +   PT  
Sbjct: 888  SPAAAYPHTSLQLPASQSALQSQQP---PREQPLPP---------APLAMPHIKPPPTTP 935

Query: 132  VNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQEKAGGPAIPSHLLST-PYPFGLSPSS- 189
            +  +   ++ +     S           PP P  K        H  S  P P  L P S 
Sbjct: 936  IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ 995

Query: 190  -----------VVQDSRFPPLNLQRP---VHHVVP-PSTVTEDYLRSFRPYHTTDDLRMS 234
                       + Q    PP     P   +H V P P      ++    P  T      +
Sbjct: 996  PLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPST 1055

Query: 235  SLPPLG-----LDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSL 289
            S PP G       P + AA    S       P P  ++ +   L     P  P P P S 
Sbjct: 1056 STPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEE-ALDDAEEPESPPPPPRSP 1114

Query: 290  PPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRRERERERERER 349
             P  P+        V  P   S S+    H +R     A        L   +  ++  E 
Sbjct: 1115 SP-EPTV-------VDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEA 1166

Query: 350  EREADREREKEREREREKEREQEKEREREKERERELER-------QREQRAREKELLAAK 402
              +A RE E++   ERE+E+E+EKERERE+ERERE ER         E R  + +L    
Sbjct: 1167 IEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPG 1226

Query: 403  ALEPSFLP----VAELHGLRGHATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPV 458
             + PSF P    +A +    G  T      SE   P          + +P    HP +  
Sbjct: 1227 HMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARP---------HVMSPTNRNHPFY-- 1275

Query: 459  PTPHHTVPSLISNH--GIFSLPSSSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVS 516
              P +    L++ H  G++++  +                   R+R LR    +R+ +  
Sbjct: 1276 -MPLNPTDPLLAYHMPGLYNVDPT------------------IRERELR----EREIRER 1312

Query: 517  EFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQ 576
            E R++ L + +  G    P E +        P  N        P +HF     L  P P 
Sbjct: 1313 EIRERELRERMKPGFEVKPPELD-----PLHPAAN--------PMEHFARHSALTIP-PT 1358

Query: 577  LHAAPTALWNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAA 619
                P A ++P     N LE  R         P    P R AA
Sbjct: 1359 AGPHPFASFHPGL---NPLERERLALAGPQLRPEMSYPDRLAA 1398



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 95/421 (22%), Positives = 134/421 (31%), Gaps = 85/421 (20%)

Query: 447  APKPVQHPLHPV--PTPHHTVPSLISNHG----IFSLPSSSAATALLIQRTNEEEKWLAR 500
            AP   Q PLH    P PH      +  H      F LP  ++     +  T+    +   
Sbjct: 838  APSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG-TSPAAAYPHT 896

Query: 501  QRRLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDP 560
              +L   +   QSQ     Q   EQ L    PP P    H     T P P    P     
Sbjct: 897  SLQLPASQSALQSQ-----QPPREQPL----PPAPLAMPHIKPPPTTPIPQLPAPQAHKH 947

Query: 561  PQHFGGPPPL-----ISPKPQL--------HAAPTALWNPVSLMDNTLETRRAESHSLHS 607
            P H  GP P      + P P L        H  P+A   P+ LM         +S  L S
Sbjct: 948  PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--------PQSQPLPS 999

Query: 608  HPA---AFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPAPLDKYQPPPPPPREGGSLEH 664
             PA       S+    P          + A + P  +   P     PPP  P    S   
Sbjct: 1000 SPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQH--PFVPGGPPPITPPTCPSTST 1057

Query: 665  QPFLPGPG--PFLAELEKSTQTILGQQRASLPQAATFGE-LSGPLKPGSPYRPPVPRAPD 721
             P  PG    P  +    S  +I G     LP      E L    +P SP  PP PR+P 
Sbjct: 1058 PPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESP--PPPPRSPS 1115

Query: 722  PAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQ 781
            P                +  + +     +Q   +Y  LD  Y+     +           
Sbjct: 1116 P----------------EPTVVDTPSHASQSARFYKHLDRGYNSCARTD----------- 1148

Query: 782  PPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPTIQSKRQTPSP 841
                       L F+ L G    +++EE + + +R+  +  RE        + +R+    
Sbjct: 1149 -----------LYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERE 1197

Query: 842  R 842
            R
Sbjct: 1198 R 1198



 Score = 38.5 bits (88), Expect = 0.039
 Identities = 15/37 (40%), Positives = 31/37 (83%), Gaps = 1/37 (2%)

Query: 353 ADREREKEREREREKEREQEKEREREKERERELERQR 389
           AD++++K++E++R+++R++E+E+ R+K RE E  R R
Sbjct: 3   ADKDKDKDKEKDRDRDRDREREK-RDKARESENSRPR 38



 Score = 37.7 bits (86), Expect = 0.067
 Identities = 14/36 (38%), Positives = 29/36 (80%), Gaps = 1/36 (2%)

Query: 342 EREREREREREADREREKEREREREKEREQEKERER 377
           ++++++++E++ DR+R++ERE+ R+K RE E  R R
Sbjct: 4   DKDKDKDKEKDRDRDRDREREK-RDKARESENSRPR 38



 Score = 37.4 bits (85), Expect = 0.088
 Identities = 14/37 (37%), Positives = 31/37 (83%), Gaps = 1/37 (2%)

Query: 358 EKEREREREKEREQEKEREREK-ERERELERQREQRA 393
           +K++++++EK+R+++++REREK ++ RE E  R +R+
Sbjct: 4   DKDKDKDKEKDRDRDRDREREKRDKARESENSRPRRS 40



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 13/36 (36%), Positives = 29/36 (80%), Gaps = 1/36 (2%)

Query: 348 EREREADREREKEREREREKEREQEKEREREKERER 383
           +++++ D+E++++R+R+RE+E+ ++K RE E  R R
Sbjct: 4   DKDKDKDKEKDRDRDRDREREK-RDKARESENSRPR 38



 Score = 34.7 bits (78), Expect = 0.57
 Identities = 10/30 (33%), Positives = 26/30 (86%)

Query: 368 EREQEKEREREKERERELERQREQRAREKE 397
           +++++K++E++++R+R+ ER++  +ARE E
Sbjct: 4   DKDKDKDKEKDRDRDRDREREKRDKARESE 33



 Score = 34.3 bits (77), Expect = 0.74
 Identities = 18/78 (23%), Positives = 40/78 (51%), Gaps = 14/78 (17%)

Query: 334 DEELRRERERERERERERE-ADREREKERERER-------------EKEREQEKEREREK 379
           D++  +E++R+R+R+RERE  D+ RE E  R R             E +  ++++ +   
Sbjct: 6   DKDKDKEKDRDRDRDREREKRDKARESENSRPRRSCTLEGGAKNYAESDHSEDEDNDNNS 65

Query: 380 ERERELERQREQRAREKE 397
               E  ++ +++  +K+
Sbjct: 66  ATAEESTKKNKKKPPKKK 83


>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
           [Homo sapiens]
          Length = 213

 Score = 74.3 bits (181), Expect = 6e-13
 Identities = 41/82 (50%), Positives = 57/82 (69%), Gaps = 15/82 (18%)

Query: 332 QMDEELRRERERERERE----------REREADREREKEREREREKERE----QEKERER 377
           Q D E  RER+R+RERE          RERE DR+R++E ERER+KERE     E +RER
Sbjct: 49  QRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRER 108

Query: 378 EKERERELERQRE-QRAREKEL 398
           +K++ERE+ER R+ +R ++KE+
Sbjct: 109 QKQKEREMERVRDREREKQKEM 130



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 44/126 (34%), Positives = 72/126 (57%), Gaps = 14/126 (11%)

Query: 321 ERMSGLSAERLQMDEELR-REREREREREREREADREREKEREREREKEREQEKEREREK 379
           E+ +    ER +  E  R R+RE ERER++ERE DR  E +RER+++KERE E+ R+RE+
Sbjct: 65  EKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRER 124

Query: 380 ERERELERQRE---QRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTR 436
           E+++E+ R+R+   +  RE+E  A +  E            R   TE+R +  E+     
Sbjct: 125 EKQKEMGRERQTDRETDRERERQAERERETG----------RERKTEDRHRERERERKRE 174

Query: 437 AEKLKD 442
            E+ ++
Sbjct: 175 RERKRE 180



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 32/71 (45%), Positives = 52/71 (73%)

Query: 320 SERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREK 379
           ++R    + E    D    R+R+R+RER RER+ DREREK+ +RE E++RE+E++R+R++
Sbjct: 27  TDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQR 86

Query: 380 ERERELERQRE 390
           E ERE +++RE
Sbjct: 87  ETERERDKERE 97



 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 33/67 (49%), Positives = 51/67 (76%), Gaps = 1/67 (1%)

Query: 332 QMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQRE- 390
           + D +  RER RER+R+RERE   +RE ER+RERE++R++++E ERE+++ERE +R  E 
Sbjct: 45  ERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTET 104

Query: 391 QRAREKE 397
            R R+K+
Sbjct: 105 DRERQKQ 111



 Score = 71.2 bits (173), Expect = 5e-12
 Identities = 34/77 (44%), Positives = 55/77 (71%), Gaps = 1/77 (1%)

Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380
           ER      ER +  E    +R  ER+R+R+RE +RER+++RERE++ +RE E++RERE++
Sbjct: 22  ERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERD 81

Query: 381 RERELERQREQRAREKE 397
           R+R+ E +RE R +E+E
Sbjct: 82  RDRQRETERE-RDKERE 97



 Score = 71.2 bits (173), Expect = 5e-12
 Identities = 45/88 (51%), Positives = 60/88 (68%), Gaps = 12/88 (13%)

Query: 321 ERMSGLSAERLQMDEELRRERERERERERE-----READREREKEREREREKEREQE-KE 374
           E+   +  ER Q D E  RERER+ ERERE     +  DR RE+ERER+RE+ER++E KE
Sbjct: 125 EKQKEMGRER-QTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKE 183

Query: 375 RER----EKERERELERQRE-QRAREKE 397
           RER    E+ER+RE +R+R+ QR  E+E
Sbjct: 184 RERHTDMERERQRETDRKRDRQRESERE 211



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 38/85 (44%), Positives = 57/85 (67%), Gaps = 7/85 (8%)

Query: 321 ERMSGLSAERLQMDEELRRERERERE----REREREADREREKEREREREKEREQEKERE 376
           +R      E    + + +R+RER RE    RERE++ DRE E++RERER+++R++E ERE
Sbjct: 32  DRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERE 91

Query: 377 REKERE--RELERQRE-QRAREKEL 398
           R+KERE  R  E  RE Q+ +E+E+
Sbjct: 92  RDKERETDRHTETDRERQKQKEREM 116



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 35/73 (47%), Positives = 52/73 (71%), Gaps = 7/73 (9%)

Query: 332 QMDEELRRERERERERE----REREADREREKEREREREKEREQEKER---EREKERERE 384
           Q + E+ R R+RERE++    RER+ DRE ++ERER+ E+ERE  +ER   +R +ERERE
Sbjct: 111 QKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERE 170

Query: 385 LERQREQRAREKE 397
            +R+RE++   KE
Sbjct: 171 RKRERERKRETKE 183



 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 36/89 (40%), Positives = 56/89 (62%), Gaps = 14/89 (15%)

Query: 322 RMSGLSAERLQMDEELRRERERER-------------EREREREADREREKEREREREKE 368
           R +    E +    E RRE +RER             ER+R+R+ +R RE++R+REREK+
Sbjct: 8   RHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQ 67

Query: 369 REQEKEREREKERERELERQREQRAREKE 397
            ++E ER+RE+ER+R+ +R+ E R R+KE
Sbjct: 68  TDREGERQRERERDRDRQRETE-RERDKE 95



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 32/70 (45%), Positives = 50/70 (71%), Gaps = 5/70 (7%)

Query: 334 DEELRREREREREREREREADREREKEREREREKEREQE-----KEREREKERERELERQ 388
           D E  +++E  RER+ +RE DRERE++ ERERE  RE++     +ERERE++RERE +R+
Sbjct: 121 DREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRE 180

Query: 389 REQRAREKEL 398
            ++R R  ++
Sbjct: 181 TKERERHTDM 190



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 34/71 (47%), Positives = 49/71 (69%), Gaps = 1/71 (1%)

Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADRERE-KEREREREKEREQEKEREREK 379
           ER      ER    E    +R RERERER+RE +R+RE KERER  + ERE+++E +R++
Sbjct: 143 ERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKR 202

Query: 380 ERERELERQRE 390
           +R+RE ER+R+
Sbjct: 203 DRQRESERERD 213



 Score = 64.3 bits (155), Expect = 7e-10
 Identities = 32/66 (48%), Positives = 46/66 (69%), Gaps = 1/66 (1%)

Query: 320 SERMSGLSAERLQMDEELRREREREREREREREA-DREREKEREREREKEREQEKERERE 378
           +ER      ER   D    RERER+RERER+RE  +RER  + ERER++E +++++R+RE
Sbjct: 148 AERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRE 207

Query: 379 KERERE 384
            ERER+
Sbjct: 208 SERERD 213



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 27/79 (34%), Positives = 46/79 (58%), Gaps = 12/79 (15%)

Query: 331 LQMDEELRREREREREREREREADREREKERER-----------EREKEREQEKEREREK 379
           ++   E R         +R+RE  RE ++ER+R           ER+++R++E+ RER++
Sbjct: 1   MESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDR 60

Query: 380 ERERELERQRE-QRAREKE 397
           +RERE +  RE +R RE+E
Sbjct: 61  DREREKQTDREGERQRERE 79



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 23/50 (46%), Positives = 32/50 (64%)

Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKE 368
           H ER      ER +  E   RER  + ERER+RE DR+R+++RE ERE++
Sbjct: 164 HRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213



 Score = 34.7 bits (78), Expect = 0.57
 Identities = 30/116 (25%), Positives = 53/116 (45%), Gaps = 16/116 (13%)

Query: 1082 QQEPPTARKGPPTQELDRDSE---------EEEEEDDEDGEDEEEVPKRKWQGIEAVFEA 1132
            ++E  T R+G   +E +RD +         ++E E D   E + E  K+K + +E V + 
Sbjct: 63   EREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDR 122

Query: 1133 YQEHIEEQNLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERER 1188
             +E  +E   ERQ  +   R  E +       AE+   +  E +++ +    ERER
Sbjct: 123  EREKQKEMGRERQTDRETDRERERQ-------AERERETGRERKTEDRHRERERER 171



 Score = 34.3 bits (77), Expect = 0.74
 Identities = 30/120 (25%), Positives = 52/120 (43%), Gaps = 2/120 (1%)

Query: 1078 QHNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHI 1137
            Q   ++E    R+     E DR+ ++++E + E   D E   K+K  G E   +   +  
Sbjct: 85   QRETERERDKERETDRHTETDRERQKQKEREMERVRDRER-EKQKEMGRERQTDRETDRE 143

Query: 1138 EEQNLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERERLQAELDHLR 1197
             E+  ER+    + R+ E RH       ++      E + +++    ERER Q E D  R
Sbjct: 144  RERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERER-QRETDRKR 202


>gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens]
          Length = 588

 Score = 74.3 bits (181), Expect = 6e-13
 Identities = 77/248 (31%), Positives = 114/248 (45%), Gaps = 52/248 (20%)

Query: 252 PSYLAPHPFPHPAFRMDDSYCLSALRSPFYPI--------PTPGSLPP-LHPSAMHLHLS 302
           P++L P PF  P   +  +  L  +  P  PI        P PG+ PP L P+    H S
Sbjct: 351 PTHLPPPPFLPPPPTVSTAPPL--IPPPGIPITVPPPGFPPPPGAPPPSLIPTIESGHSS 408

Query: 303 GV--RYPPELSHSSLAALH----SERMSGLSAERLQMDEELRREREREREREREREADRE 356
           G   R      + ++A  H    +     L     Q D   RRE++R+RER+R+RE DR+
Sbjct: 409 GYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRD 468

Query: 357 REKEREREREKEREQ-----------EKEREREKE------------RERELERQREQRA 393
           R++ERER RE+ERE+           ++ER R +E            RE+E ER RE+R 
Sbjct: 469 RDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKE-ERHRERRH 527

Query: 394 REKELLAAKALEPSFLPVAELHGLRGHATEE--RGKPSEQLTPTRAEKLKDAGLQAPKPV 451
           REKE    K+        +  +  R H +EE    +  +     R+++ K+AG + P P 
Sbjct: 528 REKEETRHKS--------SRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSE-PAPE 578

Query: 452 QHPLHPVP 459
           Q      P
Sbjct: 579 QESTEATP 586


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 138/555 (24%), Positives = 187/555 (33%), Gaps = 108/555 (19%)

Query: 49   ALSAQAAPSSSFAAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPI 108
            A S +  P  + A     L ++ +    SS  SE+  V+  A  H      P   PMGP 
Sbjct: 589  APSPRCPPPLACALQAFSLGQREDSLEVSSFCSEAL-VTCAALTHPR---VPPLQPMGPT 644

Query: 109  ------IVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPL 162
                  + PP   S    PP     P  +V  +  +     AG   S+G         P+
Sbjct: 645  CPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAG---------PV 695

Query: 163  PQEKAGGPAIPSHLLSTPYPFGLSPSSVVQDSRFPPLNLQRPVHHVV------------- 209
            P  + G P   +HL       GLS   +V     PP  L  P +H               
Sbjct: 696  PSARPGPPTTANHL-------GLSVPGLVS---VPPRLLPGPENHRAGSNEDPILAPSGT 745

Query: 210  PPSTVTEDYL---RSFRPYHTTDDLRMSS--------------------LPPLGLDPATA 246
            PP T+  D     R  RP     D   +S                    LPPL   P + 
Sbjct: 746  PPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSG 805

Query: 247  AAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYP-------IPTPGSLPPLHPSAMHL 299
            A     +   P     P    ++   L A   P  P       +P P +LPP  P  +  
Sbjct: 806  ATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPP--PQLVPE 863

Query: 300  HLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREK 359
               G   PP L    L  ++       S E  + +EE   E E E E E + E + E E+
Sbjct: 864  GTPGGGGPPALEED-LTVININS----SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEE 918

Query: 360  EREREREKEREQEKEREREKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRG 419
            E   E E+E E+ +E   E+E E E E + E    E+EL   + LE          G  G
Sbjct: 919  EYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLE---------FGTAG 969

Query: 420  HATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHP-LHPVPTPHHTV------PSLISNH 472
               EE   P   L P             P P   P + P P P   +      P      
Sbjct: 970  GEVEEGAPPPPTLPPA-----------LPPPESPPKVQPEPEPEPGLLLEVEEPGTEEER 1018

Query: 473  GIFSLPSSSAATALLIQRTNEEEKWLARQRRLRQE-KEDRQSQVSEFRQQVLEQHLDMGR 531
            G  + P + A  AL  Q   E E          QE  E+  S      ++  E   D  +
Sbjct: 1019 GADTAP-TLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQ 1077

Query: 532  PPVPAEAEHRPESTT 546
            PP    AE   E+ T
Sbjct: 1078 PPPETPAEEEMETET 1092



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 30/86 (34%), Positives = 40/86 (46%), Gaps = 10/86 (11%)

Query: 1066 PELQSSSRAPPPQHNGQQEPPTARKGPPTQELD--------RDSEEEEEEDDEDGEDEEE 1117
            P +      PPPQ   +  P     GPP  E D         D EEEEEE++E+ E+EEE
Sbjct: 847  PPVPGPVTLPPPQLVPEGTPGGG--GPPALEEDLTVININSSDEEEEEEEEEEEEEEEEE 904

Query: 1118 VPKRKWQGIEAVFEAYQEHIEEQNLE 1143
              +  ++  E   E Y E  EE+  E
Sbjct: 905  EEEEDFEEEEEDEEEYFEEEEEEEEE 930



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 19/49 (38%), Positives = 31/49 (63%)

Query: 1095 QELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQNLE 1143
            +E + + EEEEEE++ED E+EEE  +  ++  E   E ++E  EE+  E
Sbjct: 893  EEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGE 941



 Score = 34.3 bits (77), Expect = 0.74
 Identities = 69/328 (21%), Positives = 118/328 (35%), Gaps = 49/328 (14%)

Query: 651  PPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSGPLKPGS 710
            P PPPP  G +    P +   GP  A    S      ++   LP A       GPL P  
Sbjct: 797  PLPPPPPSGAT---PPPIAPTGPPTA----SPPVPAKEEPEELPAAP------GPLPPPP 843

Query: 711  PYRPPVP---RAPDPAYIYD--------EFLQQRRRLV---SKLDLEERRRREAQEKGYY 756
            P  PPVP     P P  + +          L++   ++   S  + EE    E +E+   
Sbjct: 844  PPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEE 903

Query: 757  YDLDDSYDESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRR 816
             + ++ ++E +E+E         E+   + +   E+ E  +      ++++EEL   +  
Sbjct: 904  EEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDL 963

Query: 817  K---RRRMLRERSPSPPTIQSKRQTPSPRLALSTRYSPDE----MNNSPNFEEKKKFLTI 869
            +       + E +P PPT+      P     +     P+         P  EE++   T 
Sbjct: 964  EFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTA 1023

Query: 870  FNLTHISAEKRKDKER-------------LVEMLRAMKQKALSAAVAD--SLTNSPRDSP 914
              L   +   + + ER             LVE   +     L     D       P ++P
Sbjct: 1024 PTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETP 1083

Query: 915  AVSLSEPATQQASLDVEKPVGVAASLSD 942
            A    E  T+  +L  ++    AA L+D
Sbjct: 1084 AEEEMETETEAEALQEKEQDDTAAMLAD 1111



 Score = 33.9 bits (76), Expect = 0.97
 Identities = 57/231 (24%), Positives = 80/231 (34%), Gaps = 25/231 (10%)

Query: 507 EKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTT-RPGPNRHEPGG-RDPPQHF 564
           ++ED   +VS F  + L     +  P VP      P   T  P P    P   R PP H 
Sbjct: 609 QRED-SLEVSSFCSEALVTCAALTHPRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHP 667

Query: 565 GGPPPLISPKPQLHAAPTALWNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAAVPLVK 624
            GP P +   P     P+A   P +     + + R    +  +H     P       LV 
Sbjct: 668 PGPMPSVGSMPSAGPMPSAGPMPSA---GPVPSARPGPPTTANHLGLSVPG------LVS 718

Query: 625 VERVFCPEKAEEGPRKREPAPLDKYQPPPP--PPRE--GGSLEHQPFLPGPGPFLAELEK 680
           V     P          E   L     PPP  PP E  GG +    F+       +++E 
Sbjct: 719 VPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEI 778

Query: 681 STQT-------ILGQQRASLPQAATFGELSGPLKPGSP--YRPPVPRAPDP 722
           S ++       I+ +    LP     G    P+ P  P    PPVP   +P
Sbjct: 779 SLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEP 829



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 15/33 (45%), Positives = 18/33 (54%)

Query: 1075 PPPQHNGQQEPPTARKGPPTQELDRDSEEEEEE 1107
            PPP  +G   PP A  GPPT      ++EE EE
Sbjct: 799  PPPPPSGATPPPIAPTGPPTASPPVPAKEEPEE 831



 Score = 32.3 bits (72), Expect = 2.8
 Identities = 54/247 (21%), Positives = 80/247 (32%), Gaps = 68/247 (27%)

Query: 494  EEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRH 553
            EE++   +  L +E+E+   +  E  ++V  + L+ G      E    P  T  P     
Sbjct: 932  EEEFEEEEGELEEEEEEEDEEEEEELEEV--EDLEFGTAGGEVEEGAPPPPTLPPA---- 985

Query: 554  EPGGRDPPQHFGGPPPLISPKPQ-------------------LHAAPTALWNPVSLMDNT 594
                  PP+     PP + P+P+                      APT    P +L    
Sbjct: 986  ----LPPPES----PPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLA--PEALPSQG 1035

Query: 595  LETRRAESHSLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPAPLDKYQPPPP 654
               R  ES      PAA  P ++              E+ E+G         DK QPPP 
Sbjct: 1036 EVEREGES------PAAGPPPQELVEEEPSAPPTLLEEETEDGS--------DKVQPPPE 1081

Query: 655  PPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSGPLKPGSPYRP 714
             P E                  E+E  T+    Q++     AA   +      P    +P
Sbjct: 1082 TPAE-----------------EEMETETEAEALQEKEQDDTAAMLADFID--CPPDDEKP 1122

Query: 715  PVPRAPD 721
            P P  PD
Sbjct: 1123 PPPTEPD 1129



 Score = 30.8 bits (68), Expect = 8.2
 Identities = 23/70 (32%), Positives = 30/70 (42%), Gaps = 8/70 (11%)

Query: 1074 APPPQHNGQQEPPTARKGPPTQELDRDSEEEE----EEDDEDGEDE----EEVPKRKWQG 1125
            A P Q   ++E  +   GPP QEL  +         EE+ EDG D+     E P  +   
Sbjct: 1030 ALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEME 1089

Query: 1126 IEAVFEAYQE 1135
             E   EA QE
Sbjct: 1090 TETEAEALQE 1099


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
          Length = 1341

 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 36/88 (40%), Positives = 59/88 (67%), Gaps = 5/88 (5%)

Query: 310  LSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKER 369
            L+ S +    +ER     AER +  E+ R+E+E E ++ERE+EA+RER ++ ERE+ +E 
Sbjct: 1229 LTDSQIVQKEAER-----AERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREH 1283

Query: 370  EQEKEREREKERERELERQREQRAREKE 397
             +E++RERE+ERER+   +   R R++E
Sbjct: 1284 SRERDRERERERERDRGDRDRDRERDRE 1311



 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 37/103 (35%), Positives = 62/103 (60%), Gaps = 1/103 (0%)

Query: 317  ALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERE 376
            A  +ER       R + +EE ++ERE+E ERER R+ +RE+ +E  RER++ERE+E+ER+
Sbjct: 1239 AERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERD 1298

Query: 377  R-EKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLR 418
            R +++R+RE +R+R +    ++            PV +  G R
Sbjct: 1299 RGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 31/79 (39%), Positives = 48/79 (60%), Gaps = 3/79 (3%)

Query: 339  RERERERERE-REREADREREKEREREREKEREQEKERERE--KERERELERQREQRARE 395
            R  +RE+ER  RE+ A+RERE ER      ERE ++++ RE  + R R  +R+R++RA+ 
Sbjct: 1132 RAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKS 1191

Query: 396  KELLAAKALEPSFLPVAEL 414
            KE  + K  +    P A+L
Sbjct: 1192 KEKKSEKKEKAQEEPPAKL 1210



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 38/135 (28%), Positives = 53/135 (39%), Gaps = 40/135 (29%)

Query: 279  PFYPIPTPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELR 338
            P +P P P   PP HP                                   R +  E+ R
Sbjct: 1116 PLHPPPPPPVQPPQHP-----------------------------------RAEQREQER 1140

Query: 339  REREREREREREREADREREKEREREREKEREQEKER-----EREKERERELERQREQRA 393
              RE+  ERERE E       ERE +R+K RE  + R      R KER +  E++ E++ 
Sbjct: 1141 AVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKE 1200

Query: 394  REKELLAAKALEPSF 408
            + +E   AK L+  F
Sbjct: 1201 KAQEEPPAKLLDDLF 1215



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 55/202 (27%), Positives = 74/202 (36%), Gaps = 53/202 (26%)

Query: 328 AERLQMDEELRREREREREREREREADREREKERER-----------------------E 364
           A+R    EE   E E E E + E E D E +K RE                        E
Sbjct: 263 ADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDE 322

Query: 365 REKEREQEKE---------REREKERERELERQREQRAREKELLAAKALEPSFLPVAELH 415
           R K R QE+E         R +E+ R+  L RQ++    EKE+     LE     +    
Sbjct: 323 RPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQ----EKEMKTTSPLEEEEREIKSSQ 378

Query: 416 GLRGHA--------TEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVPTPHHTVPS 467
           GL+  +        TE+R K S    P +    +    + P P+       P PH   P 
Sbjct: 379 GLKEKSKSPSPPRLTEDRKKASLVALPEQTASEE----ETPPPLLTKEASSPPPH---PQ 431

Query: 468 LISNHGIFSLPSSSAATALLIQ 489
           L S   I   P    A  +LIQ
Sbjct: 432 LHSEEEI--EPMEGPAPPVLIQ 451



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 24/145 (16%)

Query: 308 PELSHSSLAALHSERMSG-LSAERLQMDEELRREREREREREREREADR--------ERE 358
           PEL  S     HS R S  +S E+   D+E  R+ ER   R R+  A +        E E
Sbjct: 194 PELELSR----HSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEE 249

Query: 359 KERE-----------REREKEREQEKEREREKERERELERQREQRAREKELLAAKALEPS 407
           +++E           R  + E E+E+E E E++ E E      Q++RE  +L     E  
Sbjct: 250 EDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGE 309

Query: 408 FLPVAELHGLRGHATEERGKPSEQL 432
            +P  +   +     + R +  E L
Sbjct: 310 EIPRVKPEEMMDERPKTRSQEQEVL 334



 Score = 35.4 bits (80), Expect = 0.33
 Identities = 31/135 (22%), Positives = 59/135 (43%), Gaps = 11/135 (8%)

Query: 1070 SSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEA- 1128
            S    P  +   Q+ P    +    + L  + EEEEEE++E+ ++EEE      +  EA 
Sbjct: 240  SEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAP 299

Query: 1129 VFEAYQEH--------IEEQNLERQVLQTQCRRLEAR--HYSLSLTAEQLSHSVAELRSQ 1178
            + + ++E          EE   ER   ++Q + +  R   ++ S    + SH   + + +
Sbjct: 300  ILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEK 359

Query: 1179 KQKMVSERERLQAEL 1193
            + K  S  E  + E+
Sbjct: 360  EMKTTSPLEEEEREI 374



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 48/217 (22%), Positives = 80/217 (36%), Gaps = 29/217 (13%)

Query: 327 SAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELE 386
           S E  +     R+++E+E +     E +    K  +  +EK +     R  E  ++  L 
Sbjct: 343 SQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLV 402

Query: 387 RQREQRAREKE----LLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKD 442
              EQ A E+E    LL  +A  P   P  +LH      +EE  +P E   P        
Sbjct: 403 ALPEQTASEEETPPPLLTKEASSPP--PHPQLH------SEEEIEPMEGPAP-------- 446

Query: 443 AGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQR 502
                  PV   L P  T   T   L+S H +  +   S  ++    +     + +  + 
Sbjct: 447 -------PVLIQLSPPNTDADTRELLVSQHTVQLVGGLSPLSSPSDTKAESPAEKVPEES 499

Query: 503 RLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAE 539
            L   ++   +  S   Q+ LE   D    P+P + E
Sbjct: 500 VLPLVQKSTLADYS--AQKDLEPESDRSAQPLPLKIE 534


>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 285

 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 35/74 (47%), Positives = 56/74 (75%), Gaps = 2/74 (2%)

Query: 320 SERMSGLSAERLQMDEELRRERERERERERE-READREREKEREREREKEREQEKERERE 378
           +ER      ER Q   E RR+R+RER+RE+E RE DR+R+KERE++R +ERE  ++R++E
Sbjct: 169 TERYRDRERER-QKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKE 227

Query: 379 KERERELERQREQR 392
           ++RER+ E+ R+++
Sbjct: 228 RDRERQREKDRDRQ 241



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 36/102 (35%), Positives = 66/102 (64%), Gaps = 2/102 (1%)

Query: 299 LHLSGVRYPPELSHSSLAALHSERMSGLSAER-LQMDEELRREREREREREREREADRER 357
           L L G R  P +          ER    + ER  + D E+ ++R+R+R+R+RER+  R+R
Sbjct: 45  LILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDR 104

Query: 358 EKEREREREKEREQEKEREREKERERELERQRE-QRAREKEL 398
           +++RER  +++RE E ER+ E+ER+R+ +R+++ +R R++E+
Sbjct: 105 DRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREI 146



 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 32/80 (40%), Positives = 55/80 (68%), Gaps = 11/80 (13%)

Query: 329 ERLQMDEELRREREREREREREREADRER----EKERERERE-------KEREQEKERER 377
           E  +   + +RE++RER+R+RE   D++R    EK+R+RERE       ++RE+E++++R
Sbjct: 124 EERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQR 183

Query: 378 EKERERELERQREQRAREKE 397
           E  R+R+ ERQRE+  RE++
Sbjct: 184 ETRRDRDRERQREKEDRERD 203



 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 42/104 (40%), Positives = 66/104 (63%), Gaps = 20/104 (19%)

Query: 321 ERMSGLSAERLQMDEELRRERERE-------REREREREADRE--REKEREREREKE--- 368
           +R  G+  +R +++ E  R+RERE       R+RERER+  RE  R+++RER+REKE   
Sbjct: 143 QREIGIDKDR-EIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRE 201

Query: 369 --REQEKEREREKERERELERQRE-----QRAREKELLAAKALE 405
             R+++KERE+++ RERE  R R+     +R REK+    KA++
Sbjct: 202 RDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAID 245



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 28/65 (43%), Positives = 50/65 (76%), Gaps = 1/65 (1%)

Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393
           D + +RER  +R+RE E E   ERE++R+R+REK+RE++++RE   +++RE+E +++ R 
Sbjct: 103 DRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKD-RD 161

Query: 394 REKEL 398
           RE+E+
Sbjct: 162 REREM 166



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 35/84 (41%), Positives = 54/84 (64%), Gaps = 20/84 (23%)

Query: 334 DEELRREREREREREREREADREREKERERE----REKEREQEKEREREKE--------- 380
           D E   ER+ ERER+R+R+ +++RE++R+RE    +++E E EK+R+RE+E         
Sbjct: 115 DRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRD 174

Query: 381 RERELERQRE-------QRAREKE 397
           RERE ++QRE       +R REKE
Sbjct: 175 RERERQKQRETRRDRDRERQREKE 198



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 27/64 (42%), Positives = 45/64 (70%)

Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393
           D +   E ER+ ERER+R+  RE+++ER+R+RE   ++++E E EK+R+RE E    +R 
Sbjct: 113 DRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERY 172

Query: 394 REKE 397
           R++E
Sbjct: 173 RDRE 176


>gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo
           sapiens]
          Length = 142

 Score = 71.2 bits (173), Expect = 5e-12
 Identities = 42/101 (41%), Positives = 57/101 (56%), Gaps = 16/101 (15%)

Query: 307 PPELSHSSLAALHSERMSGLSAERLQMDEELRRERER--EREREREREADREREKERERE 364
           PP L HS         M+G SA + Q  EE RRE +R  E+ RE +R   + REKE E+E
Sbjct: 50  PPTLRHS---------MAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKE 100

Query: 365 REKEREQEKEREREKERERELE-----RQREQRAREKELLA 400
            E+E E+E+E E E+E E E+      R+RE    EK L++
Sbjct: 101 EEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLIS 141



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 3/80 (3%)

Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERE---R 377
           E ++GL+     + EE    R         +   RE ++  E+ RE++R +EK RE   R
Sbjct: 34  ENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRR 93

Query: 378 EKERERELERQREQRAREKE 397
           EKE E+E E + E+   E+E
Sbjct: 94  EKEEEKEEEEEEEEEEEEEE 113



 Score = 32.0 bits (71), Expect = 3.7
 Identities = 13/30 (43%), Positives = 22/30 (73%)

Query: 1089 RKGPPTQELDRDSEEEEEEDDEDGEDEEEV 1118
            R+    ++ + + EEEEEE++E+ E+EEEV
Sbjct: 92   RREKEEEKEEEEEEEEEEEEEEEEEEEEEV 121



 Score = 31.6 bits (70), Expect = 4.8
 Identities = 13/29 (44%), Positives = 21/29 (72%)

Query: 1089 RKGPPTQELDRDSEEEEEEDDEDGEDEEE 1117
            R+    +E + + EEEEEE++E+ E+EEE
Sbjct: 87   RREGKRREKEEEKEEEEEEEEEEEEEEEE 115



 Score = 31.6 bits (70), Expect = 4.8
 Identities = 13/29 (44%), Positives = 21/29 (72%)

Query: 1089 RKGPPTQELDRDSEEEEEEDDEDGEDEEE 1117
            R+G   ++ +   EEEEEE++E+ E+EEE
Sbjct: 88   REGKRREKEEEKEEEEEEEEEEEEEEEEE 116



 Score = 30.8 bits (68), Expect = 8.2
 Identities = 16/59 (27%), Positives = 32/59 (54%)

Query: 1089 RKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQNLERQVL 1147
            R+    +E  R  +EEE+E++E+ E+EEE  + + +  E  F       E +  E++++
Sbjct: 82   RREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLI 140


>gi|125988409 RED protein [Homo sapiens]
          Length = 557

 Score = 70.9 bits (172), Expect = 7e-12
 Identities = 34/63 (53%), Positives = 48/63 (76%), Gaps = 2/63 (3%)

Query: 327 SAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELE 386
           S  +   D+E  RER RERER+RER+ DR+RE+ERER+RE+ERE+++ERE EK+R    E
Sbjct: 328 STTKTPRDKE--RERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFE 385

Query: 387 RQR 389
           + +
Sbjct: 386 KPK 388



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 25/49 (51%), Positives = 44/49 (89%)

Query: 345 REREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393
           R++ERER  +RER++ER+R+R++ERE+E++RERE+ER+RE E ++++ +
Sbjct: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHS 382



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 24/46 (52%), Positives = 41/46 (89%)

Query: 349 REREADREREKEREREREKEREQEKEREREKERERELERQREQRAR 394
           R++E +R RE+ER+RER+++R++E+ERER++ERERE +R+RE+  +
Sbjct: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKK 379



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 25/46 (54%), Positives = 39/46 (84%)

Query: 351 READREREKEREREREKEREQEKEREREKERERELERQREQRAREK 396
           R+ +RER +ERER+RE++R++++ERERE++RERE ER RE+   +K
Sbjct: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKK 379



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 37/98 (37%), Positives = 57/98 (58%), Gaps = 8/98 (8%)

Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393
           + E  RER+R+R+RERERE DRERE+ER+RERE+E+++    E+ K  +  ++  +    
Sbjct: 343 ERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGP-G 401

Query: 394 REKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQ 431
             KEL+  K++   F   A   G     TE   KP ++
Sbjct: 402 STKELI--KSINEKFAGSAGWEG-----TESLKKPEDK 432



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 26/44 (59%), Positives = 40/44 (90%), Gaps = 1/44 (2%)

Query: 354 DREREKEREREREKEREQEKEREREKERERELERQREQRAREKE 397
           D+ERE+ RERER++ER+++++RERE+ER+RE ER+R+ R RE+E
Sbjct: 335 DKERERYRERERDRERDRDRDRERERERDRERERERD-REREEE 377



 Score = 35.4 bits (80), Expect = 0.33
 Identities = 21/54 (38%), Positives = 30/54 (55%), Gaps = 1/54 (1%)

Query: 343 REREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREK 396
           + R  E  RE + E E    R R+K+    K R++E EREREL  +   RA+E+
Sbjct: 54  KSRHHEMPREYN-EDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKER 106



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 28/79 (35%), Positives = 41/79 (51%), Gaps = 4/79 (5%)

Query: 339 RERERERE-REREREADREREKEREREREKEREQEKERE-REKERERELERQR--EQRAR 394
           R  E  RE  E E  A R R+K+    + +++E E+ERE  EK R+R  ER+    +   
Sbjct: 56  RHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYE 115

Query: 395 EKELLAAKALEPSFLPVAE 413
           E EL++  A   +  P AE
Sbjct: 116 ETELISTTANYRAVGPTAE 134


>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
          Length = 1220

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 41/95 (43%), Positives = 61/95 (64%), Gaps = 4/95 (4%)

Query: 309 ELSHSSLAALHSERMSGLSAERLQMDEELRRERER-EREREREREADREREKEREREREK 367
           EL     A L  +R       +L+  E+ R+ERER E+ER+R+ E +++ EK+RE ER++
Sbjct: 364 ELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQR 423

Query: 368 EREQEKEREREKERERELERQRE---QRAREKELL 399
           E E+ KE ER +  +RELERQR+   +R R +ELL
Sbjct: 424 EEERRKEIERREAAKRELERQRQLEWERNRRQELL 458



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 42/119 (35%), Positives = 68/119 (57%), Gaps = 10/119 (8%)

Query: 329 ERLQMDEELRRERERERER-EREREADREREKEREREREKEREQEKER----EREKERER 383
           ER  ++ E RR+   E++R E+ER A  ER ++  +ERE++ EQE++R    E++ E++R
Sbjct: 359 ERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQ-EQERKRQLELEKQLEKQR 417

Query: 384 ELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATE---ERGKPSEQLTPTRAEK 439
           ELERQRE+  R KE+   +A +       +L   R    E   +R K  E +   +A+K
Sbjct: 418 ELERQREEE-RRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKK 475



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 40/131 (30%), Positives = 63/131 (48%), Gaps = 11/131 (8%)

Query: 315 LAALHSERMSGLSAERLQMDE----ELRREREREREREREREADREREKEREREREKERE 370
           LA L          ER + +     EL ++ E++RE ER+RE +R +E ER    ++E E
Sbjct: 383 LAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELE 442

Query: 371 QEKEREREKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSE 430
           ++++ E E+ R +EL  QR +   +  +L AK     F    EL  L     +  GK  +
Sbjct: 443 RQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEF----ELEALNDKKHQLEGKLQD 498

Query: 431 ---QLTPTRAE 438
              +LT  R E
Sbjct: 499 IRCRLTTQRQE 509



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 33/119 (27%), Positives = 61/119 (51%), Gaps = 9/119 (7%)

Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380
           ++   + AERL+  E+ R+  E E+++E   EA R R +ER+++  +  +QE E +R ++
Sbjct: 620 QKQKSMEAERLKQKEQERKIIELEKQKE---EAQR-RAQERDKQWLEHVQQEDEHQRPRK 675

Query: 381 RERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEK 439
              E + +RE+  ++K+       E       +  G   H  +E  KP+ Q   + AEK
Sbjct: 676 LHEEEKLKREESVKKKD-----GEEKGKQEAQDKLGRLFHQHQEPAKPAVQAPWSTAEK 729



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 44/166 (26%), Positives = 75/166 (45%), Gaps = 30/166 (18%)

Query: 296 AMHL---HLSGVRYPPEL-------------SHSSLAALHSERMSG-LSAERLQMDEELR 338
           AMHL    +SG   PP L             S S ++ + S  +   L  E +  DE+ +
Sbjct: 282 AMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQ 341

Query: 339 RERE-----REREREREREADREREKEREREREKER-EQEKEREREKERERELERQREQR 392
            E++      +++RE     + E EK R+   E++R EQE+  + E+  +   ER+R+++
Sbjct: 342 LEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQ 401

Query: 393 AREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAE 438
            R+++L   K LE       +   L     EER K  E+    + E
Sbjct: 402 ERKRQLELEKQLE-------KQRELERQREEERRKEIERREAAKRE 440



 Score = 33.9 bits (76), Expect = 0.97
 Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 7/76 (9%)

Query: 485 ALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQV-LEQHLDMGRPPVPAEAEHRPE 543
           ALL Q+  E+E+ LA+  R  QE+++R+ Q  E ++Q+ LE+ L+  R     E E + E
Sbjct: 371 ALLEQQRKEQER-LAQLERAEQERKERERQEQERKRQLELEKQLEKQR-----ELERQRE 424

Query: 544 STTRPGPNRHEPGGRD 559
              R    R E   R+
Sbjct: 425 EERRKEIERREAAKRE 440



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 33/116 (28%), Positives = 61/116 (52%), Gaps = 11/116 (9%)

Query: 1095 QELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQNLERQ---VLQTQC 1151
            +EL+R  EEE  ++ E  E  +   +R+ Q +E      QE + ++N E++   VL+ + 
Sbjct: 417  RELERQREEERRKEIERREAAKRELERQRQ-LEWERNRRQELLNQRNKEQEDIVVLKAKK 475

Query: 1152 RRLEARHYSLSLTAEQLSHSVAELR----SQKQKMVS---ERERLQAELDHLRKCL 1200
            + LE    +L+    QL   + ++R    +Q+Q++ S    RE   AE+ HL++ L
Sbjct: 476  KTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQL 531



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 32/123 (26%), Positives = 56/123 (45%), Gaps = 24/123 (19%)

Query: 330 RLQMDEELRRERERERERE---------REREADREREKEREREREKEREQEKER---ER 377
           R Q+DE  +  R + +E +         RE    ++ +K++  E E+ +++E+ER   E 
Sbjct: 583 RDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIEL 642

Query: 378 EKERERELERQREQRAREKELLAAKALEPSFLPVAELH---------GLRGHATEERGKP 428
           EK++E   E QR  + R+K+ L     E       +LH          ++    EE+GK 
Sbjct: 643 EKQKE---EAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQ 699

Query: 429 SEQ 431
             Q
Sbjct: 700 EAQ 702


>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
          Length = 1721

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 41/95 (43%), Positives = 61/95 (64%), Gaps = 4/95 (4%)

Query: 309 ELSHSSLAALHSERMSGLSAERLQMDEELRRERER-EREREREREADREREKEREREREK 367
           EL     A L  +R       +L+  E+ R+ERER E+ER+R+ E +++ EK+RE ER++
Sbjct: 364 ELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQR 423

Query: 368 EREQEKEREREKERERELERQRE---QRAREKELL 399
           E E+ KE ER +  +RELERQR+   +R R +ELL
Sbjct: 424 EEERRKEIERREAAKRELERQRQLEWERNRRQELL 458



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 42/119 (35%), Positives = 68/119 (57%), Gaps = 10/119 (8%)

Query: 329 ERLQMDEELRRERERERER-EREREADREREKEREREREKEREQEKER----EREKERER 383
           ER  ++ E RR+   E++R E+ER A  ER ++  +ERE++ EQE++R    E++ E++R
Sbjct: 359 ERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQ-EQERKRQLELEKQLEKQR 417

Query: 384 ELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATE---ERGKPSEQLTPTRAEK 439
           ELERQRE+  R KE+   +A +       +L   R    E   +R K  E +   +A+K
Sbjct: 418 ELERQREEE-RRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKK 475



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 40/131 (30%), Positives = 63/131 (48%), Gaps = 11/131 (8%)

Query: 315 LAALHSERMSGLSAERLQMDE----ELRREREREREREREREADREREKEREREREKERE 370
           LA L          ER + +     EL ++ E++RE ER+RE +R +E ER    ++E E
Sbjct: 383 LAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELE 442

Query: 371 QEKEREREKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSE 430
           ++++ E E+ R +EL  QR +   +  +L AK     F    EL  L     +  GK  +
Sbjct: 443 RQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEF----ELEALNDKKHQLEGKLQD 498

Query: 431 ---QLTPTRAE 438
              +LT  R E
Sbjct: 499 IRCRLTTQRQE 509



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 33/119 (27%), Positives = 61/119 (51%), Gaps = 9/119 (7%)

Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380
           ++   + AERL+  E+ R+  E E+++E   EA R R +ER+++  +  +QE E +R ++
Sbjct: 620 QKQKSMEAERLKQKEQERKIIELEKQKE---EAQR-RAQERDKQWLEHVQQEDEHQRPRK 675

Query: 381 RERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEK 439
              E + +RE+  ++K+       E       +  G   H  +E  KP+ Q   + AEK
Sbjct: 676 LHEEEKLKREESVKKKD-----GEEKGKQEAQDKLGRLFHQHQEPAKPAVQAPWSTAEK 729



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 44/166 (26%), Positives = 75/166 (45%), Gaps = 30/166 (18%)

Query: 296 AMHL---HLSGVRYPPEL-------------SHSSLAALHSERMSG-LSAERLQMDEELR 338
           AMHL    +SG   PP L             S S ++ + S  +   L  E +  DE+ +
Sbjct: 282 AMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQ 341

Query: 339 RERE-----REREREREREADREREKEREREREKER-EQEKEREREKERERELERQREQR 392
            E++      +++RE     + E EK R+   E++R EQE+  + E+  +   ER+R+++
Sbjct: 342 LEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQ 401

Query: 393 AREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAE 438
            R+++L   K LE       +   L     EER K  E+    + E
Sbjct: 402 ERKRQLELEKQLE-------KQRELERQREEERRKEIERREAAKRE 440



 Score = 33.9 bits (76), Expect = 0.97
 Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 7/76 (9%)

Query: 485 ALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQV-LEQHLDMGRPPVPAEAEHRPE 543
           ALL Q+  E+E+ LA+  R  QE+++R+ Q  E ++Q+ LE+ L+  R     E E + E
Sbjct: 371 ALLEQQRKEQER-LAQLERAEQERKERERQEQERKRQLELEKQLEKQR-----ELERQRE 424

Query: 544 STTRPGPNRHEPGGRD 559
              R    R E   R+
Sbjct: 425 EERRKEIERREAAKRE 440



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 33/116 (28%), Positives = 61/116 (52%), Gaps = 11/116 (9%)

Query: 1095 QELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQNLERQ---VLQTQC 1151
            +EL+R  EEE  ++ E  E  +   +R+ Q +E      QE + ++N E++   VL+ + 
Sbjct: 417  RELERQREEERRKEIERREAAKRELERQRQ-LEWERNRRQELLNQRNKEQEDIVVLKAKK 475

Query: 1152 RRLEARHYSLSLTAEQLSHSVAELR----SQKQKMVS---ERERLQAELDHLRKCL 1200
            + LE    +L+    QL   + ++R    +Q+Q++ S    RE   AE+ HL++ L
Sbjct: 476  KTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQL 531



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 32/123 (26%), Positives = 56/123 (45%), Gaps = 24/123 (19%)

Query: 330 RLQMDEELRRERERERERE---------REREADREREKEREREREKEREQEKER---ER 377
           R Q+DE  +  R + +E +         RE    ++ +K++  E E+ +++E+ER   E 
Sbjct: 583 RDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIEL 642

Query: 378 EKERERELERQREQRAREKELLAAKALEPSFLPVAELH---------GLRGHATEERGKP 428
           EK++E   E QR  + R+K+ L     E       +LH          ++    EE+GK 
Sbjct: 643 EKQKE---EAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQ 699

Query: 429 SEQ 431
             Q
Sbjct: 700 EAQ 702


>gi|34878777 ring finger protein 20 [Homo sapiens]
          Length = 975

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 40/100 (40%), Positives = 58/100 (58%), Gaps = 1/100 (1%)

Query: 307 PPELSHSSLAALHSERMSGLSAERLQMDEELRRERERERER-EREREADREREKERERER 365
           P EL   S         S  S E     +  R E ERERER E+ERE +REREKE+ERER
Sbjct: 533 PAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKEREREREREKEKERER 592

Query: 366 EKEREQEKEREREKERERELERQREQRAREKELLAAKALE 405
           EK++ +E E+ER+  +++E  +  + R +E E++    +E
Sbjct: 593 EKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKIE 632



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 43/149 (28%), Positives = 69/149 (46%), Gaps = 30/149 (20%)

Query: 311 SHSSLAALHSERMSGLSAERLQMDEEL-RREREREREREREREADREREKEREREREKER 369
           S SS +    E  + + ++R + + E  RRE+ERERERERE+E +REREK++ +E EKER
Sbjct: 545 SQSSASKASQEDANEIKSKRDEEERERERREKEREREREREKEKEREREKQKLKESEKER 604

Query: 370 EQEKER---------------------------EREKERERELERQREQRAREKELLAAK 402
           +  K++                           E +KE +  L+  R     +++ +   
Sbjct: 605 DSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLM 664

Query: 403 ALEPSFLPVAELHGLRGHATEERGKPSEQ 431
           A E      AEL  LR    +   K  ++
Sbjct: 665 AAEKK--SKAELEDLRQRLKDLEDKEKKE 691



 Score = 33.9 bits (76), Expect = 0.97
 Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 7/97 (7%)

Query: 304 VRYPPELSHSSLAALHSERMSGLSAERLQMDEELRRERERERERERE---READREREKE 360
           +RY  +L  +      +   SG +  + Q   E  ++   E + + E    ++   +  +
Sbjct: 495 LRYKRKLREAQSDLNKTRLRSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKASQ 554

Query: 361 REREREKEREQEKEREREKERERELERQREQRAREKE 397
            +    K +  E+ERERE+   RE ER+RE R REKE
Sbjct: 555 EDANEIKSKRDEEERERER---REKERERE-REREKE 587



 Score = 33.9 bits (76), Expect = 0.97
 Identities = 31/133 (23%), Positives = 54/133 (40%), Gaps = 4/133 (3%)

Query: 321 ERMSGLSAERLQMDEELRRER---EREREREREREADREREKEREREREKEREQEKE-RE 376
           E  S L+  RL+    L + +   E  ++   E + D E    +    +  +E   E + 
Sbjct: 503 EAQSDLNKTRLRSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKS 562

Query: 377 REKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTR 436
           +  E ERE ER+ ++R RE+E    K  E     + E    R  A ++     +      
Sbjct: 563 KRDEEERERERREKEREREREREKEKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKE 622

Query: 437 AEKLKDAGLQAPK 449
           AE +K   ++  K
Sbjct: 623 AEIIKQLKIELKK 635



 Score = 31.6 bits (70), Expect = 4.8
 Identities = 29/145 (20%), Positives = 64/145 (44%), Gaps = 11/145 (7%)

Query: 1066 PELQSSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQG 1125
            P+ +  S         Q++    +     +E +R+  E+E E + + E E+E  + K + 
Sbjct: 538  PDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKEREREREREKEKEREREKQKL 597

Query: 1126 IEAVFEAYQ-------EHIEEQNLERQV---LQTQCRRLEARHYSLSLTAEQLSHSVAEL 1175
             E+  E          +H + +  E ++   L+ + ++ +     + L  +    +  E 
Sbjct: 598  KESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQ 657

Query: 1176 RSQKQKMVSERERLQAELDHLRKCL 1200
            R + Q M +E+ + +AEL+ LR+ L
Sbjct: 658  RDKVQLMAAEK-KSKAELEDLRQRL 681


>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 2 [Homo sapiens]
          Length = 1320

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 67/234 (28%), Positives = 104/234 (44%), Gaps = 32/234 (13%)

Query: 315 LAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKE 374
           L A   +R+     +R +++E+ RRERE  R++ERE+    + EK R  E E+ R++E+E
Sbjct: 391 LLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEE 450

Query: 375 REREKERERELERQRE--QRAREKELLAAKALEPSFL-PVAELHGLRGHATEERGKPSEQ 431
           R R +E +R +ER++E  +R  E+E    + L+   L   A L   R    EE  +    
Sbjct: 451 RRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERL 510

Query: 432 LTPTRAEKLKDAGLQAPKPVQHPLH----PVPTPHHTVPSLISNHGIFSLPSSSAATALL 487
               + E+     LQ      HP H    P P    + PS       F  P   A     
Sbjct: 511 QRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPS-------FHAPEPKA----- 558

Query: 488 IQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQ--QVLEQHLDMGRPPVPAEAE 539
               + E    AR+   R  K +  S  ++ +Q  +VLE       PPVP+ +E
Sbjct: 559 ----HYEPADRAREVEDRFRKTNHSSPEAQSKQTGRVLE-------PPVPSRSE 601



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 25/78 (32%), Positives = 48/78 (61%)

Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERERE 378
           + ER   L  ++L  +++LR + E +R+   ER+   E++KE+ R  E+++ +E+E  R+
Sbjct: 363 NKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQ 422

Query: 379 KERERELERQREQRAREK 396
           +ERE+    Q E+R  E+
Sbjct: 423 QEREQRRREQEEKRRLEE 440



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 24/68 (35%), Positives = 44/68 (64%)

Query: 330 RLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQR 389
           +L  + + R E+++E+ R  E +  RERE  R++ERE+ R +++E+ R +E ER  + + 
Sbjct: 390 QLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEE 449

Query: 390 EQRAREKE 397
           E+R  E+E
Sbjct: 450 ERRRAEEE 457



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 58/237 (24%), Positives = 97/237 (40%), Gaps = 34/237 (14%)

Query: 326 LSAERLQMDEELRREREREREREREREA-DREREKEREREREKEREQEKEREREKERERE 384
           L  E  +  E LRR++  + ++ RE+E   R+   ER++  E+++EQ +  E ++ RERE
Sbjct: 359 LQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRRERE 418

Query: 385 LERQ--REQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKD 442
             RQ  REQR RE+E    + LE       EL   R    E R          RAE+ K 
Sbjct: 419 ARRQQEREQRRREQE--EKRRLE-------ELERRRKEEEERR----------RAEEEKR 459

Query: 443 AGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQR 502
              +  + ++  L         +   +               A+L++    E +   +  
Sbjct: 460 RVEREQEYIRRQLEEEQRHLEVLQQQLLQE-----------QAMLLECRWREMEEHRQAE 508

Query: 503 RLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRH-EPGGR 558
           RL+++ +  Q+ +   +      H    + P P + E    S   P P  H EP  R
Sbjct: 509 RLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADR 565



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 26/79 (32%), Positives = 47/79 (59%), Gaps = 3/79 (3%)

Query: 322 RMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERE---RE 378
           R   L  ++L+  EE +R+   ER++  E++ ++ R  E ++ RE+E  +++ERE   RE
Sbjct: 372 RQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRRE 431

Query: 379 KERERELERQREQRAREKE 397
           +E +R LE    +R  E+E
Sbjct: 432 QEEKRRLEELERRRKEEEE 450



 Score = 38.1 bits (87), Expect = 0.051
 Identities = 65/273 (23%), Positives = 105/273 (38%), Gaps = 27/273 (9%)

Query: 731 QQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDE----EEVRAHLRCVAEQPPLKL 786
           Q+R R   +    E+RRRE +EK    +L+    E +E    EE +  +    E    +L
Sbjct: 413 QRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQL 472

Query: 787 DTSSEKLEFLQLFGLTTQ------QQKEELVAQKRRKRRRMLRERSPSPPTIQSKRQTPS 840
           +     LE LQ   L  Q      + +E    ++  + +R L++      ++Q   + P 
Sbjct: 473 EEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPH 532

Query: 841 PRLALSTRYSPDEMNNSPNF---EEKKKFLTIFNLTHISAEKRKDKERLVEMLRAMKQKA 897
           P+ +      P +  + P+F   E K  +        +    RK      E       + 
Sbjct: 533 PQHSQQPP-PPQQERSKPSFHAPEPKAHYEPADRAREVEDRFRKTNHSSPEAQSKQTGRV 591

Query: 898 LSAAV---ADSLTNSPRDSPAVSLSEPATQQ------ASL-DVEKPVGVAASLSDIPKAA 947
           L   V   ++S +N   +S   +L  PA  Q      ASL +   PV  + S SD     
Sbjct: 592 LEPPVPSRSESFSNGNSESVHPALQRPAEPQVQWSHLASLKNNVSPVSRSHSFSDPSPKF 651

Query: 948 EPGKLEQVRPQELSRVQELAPASGEKARLSEAP 980
               L    P   SR + L+ +S  K   SEAP
Sbjct: 652 AHHHLRSQDPCPPSRSEVLSQSSDSK---SEAP 681



 Score = 35.0 bits (79), Expect = 0.44
 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 16/125 (12%)

Query: 1082 QQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHI---- 1137
            Q+    AR+    ++  R+ EE+   ++ +   +EE  +R+ +  +   E  QE+I    
Sbjct: 413  QRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQL 472

Query: 1138 -EEQN----LERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERERLQAE 1192
             EEQ     L++Q+LQ Q   LE R        E   H  AE R Q+Q    +   L  +
Sbjct: 473  EEEQRHLEVLQQQLLQEQAMLLECR------WREMEEHRQAE-RLQRQLQQEQAYLLSLQ 525

Query: 1193 LDHLR 1197
             DH R
Sbjct: 526  HDHRR 530



 Score = 31.2 bits (69), Expect = 6.3
 Identities = 27/116 (23%), Positives = 48/116 (41%), Gaps = 4/116 (3%)

Query: 1079 HNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIE 1138
            H  +       K     E     EEEEE  +++GE    V       +   F   Q+  +
Sbjct: 305  HIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENK 364

Query: 1139 EQN--LERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERERLQAE 1192
            E++  L RQ L  + +  E   Y   L AE+      E + ++++ + E++R + E
Sbjct: 365  ERSEALRRQQLLQEQQLREQEEYKRQLLAERQKR--IEQQKEQRRRLEEQQRRERE 418


>gi|14670268 RD RNA-binding protein [Homo sapiens]
          Length = 380

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 26/58 (44%), Positives = 49/58 (84%)

Query: 340 EREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKE 397
           ER R+R+R+RER+ DR+R+++RER+R+++R+++++RER+++RER+ +R RE   R  +
Sbjct: 193 ERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSD 250



 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 27/73 (36%), Positives = 52/73 (71%)

Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERERE 378
           + ER    S+          R  ER R+R+R+RE DR+R+++R+RER+++R+++++R+RE
Sbjct: 170 YEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRE 229

Query: 379 KERERELERQREQ 391
           ++R+RE +R R++
Sbjct: 230 RDRDRERDRDRDR 242



 Score = 67.4 bits (163), Expect = 8e-11
 Identities = 24/55 (43%), Positives = 48/55 (87%)

Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQ 388
           D    R R+R+R+RER+R+ DR+R++ER+R+R+++R++++ER+R++ER+R+ +R+
Sbjct: 189 DRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 30/86 (34%), Positives = 54/86 (62%), Gaps = 1/86 (1%)

Query: 311 SHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKERE 370
           +HSS +   S             D +  R+R+R+R+R+RER+ DR+R+++R+RER+++RE
Sbjct: 176 AHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRE 235

Query: 371 QEKEREREKERERELERQREQRAREK 396
           ++++R+RE    R  +   E+RA  K
Sbjct: 236 RDRDRDREGPFRRS-DSFPERRAPRK 260



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 26/76 (34%), Positives = 49/76 (64%)

Query: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393
           D E  R+R+R+R+RER+R+ DR+R+++RER+R++ER+++++RE    R      +R  R 
Sbjct: 201 DRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRK 260

Query: 394 REKELLAAKALEPSFL 409
                +  + + P+ L
Sbjct: 261 GNTLYVYGEDMTPTLL 276


>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing B [Homo sapiens]
          Length = 546

 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 41/82 (50%), Positives = 51/82 (62%), Gaps = 8/82 (9%)

Query: 321 ERMSGLSAER-LQMDEELRREREREREREREREADR-----EREKEREREREKEREQEKE 374
           ER    S +R L+      RER R R R R+R+ DR     EREKE ER R ++R+ +KE
Sbjct: 314 ERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKE 373

Query: 375 R--EREKERERELERQREQRAR 394
           R  EREKERER  ER +EQR+R
Sbjct: 374 RGNEREKERERSRERSKEQRSR 395



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 30/75 (40%), Positives = 46/75 (61%)

Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380
           ER    S  R +  +   R+RERE+E ER R  DR+ +KER  EREKERE+ +ER +E+ 
Sbjct: 334 ERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQR 393

Query: 381 RERELERQREQRARE 395
              E+E ++ +  ++
Sbjct: 394 SRGEVEEKKHKEDKD 408



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 30/77 (38%), Positives = 45/77 (58%)

Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380
           ER    S ER +     R  +   R+R+RERE + ER + R+R+ +KER  E+E+ERE+ 
Sbjct: 326 ERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERS 385

Query: 381 RERELERQREQRAREKE 397
           RER  E++      EK+
Sbjct: 386 RERSKEQRSRGEVEEKK 402



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 37/126 (29%), Positives = 62/126 (49%), Gaps = 2/126 (1%)

Query: 319 HSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKERER- 377
           H  R      +  + D +  RE+E ER R R+R+ D+ER  ERE+ERE+ RE+ KE+   
Sbjct: 336 HRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSR 395

Query: 378 -EKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTR 436
            E E ++  E + ++R R+ +  + K  + S     E        +   GK S   +  +
Sbjct: 396 GEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEK 455

Query: 437 AEKLKD 442
           + K K+
Sbjct: 456 SSKHKN 461



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 31/82 (37%), Positives = 44/82 (53%), Gaps = 4/82 (4%)

Query: 319 HSERMSGLSAER-LQMDEELRREREREREREREREADREREKEREREREKEREQEKERER 377
           H ER    S  R L      RR R R   RE    +  +RE ERE+ER++   + KERE+
Sbjct: 254 HVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREK 313

Query: 378 EKERERELER---QREQRAREK 396
           E+ R R ++R   +R  R+RE+
Sbjct: 314 ERRRSRSIDRGLERRRSRSRER 335



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 33/100 (33%), Positives = 47/100 (47%), Gaps = 9/100 (9%)

Query: 335 EELRREREREREREREREADREREKEREREREKEREQ------EKEREREKERERELERQ 388
           EE+ R  ER R R   R     R   R R R   RE       ++E EREKER+R LER+
Sbjct: 249 EEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQR-LERE 307

Query: 389 REQRAREKELLAA--KALEPSFLPVAELHGLRGHATEERG 426
            ++R +E+    +  + LE       E H  R  + + +G
Sbjct: 308 AKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKG 347



 Score = 38.5 bits (88), Expect = 0.039
 Identities = 18/56 (32%), Positives = 34/56 (60%), Gaps = 4/56 (7%)

Query: 346 EREREREADREREKEREREREKEREQEKEREREKERERELERQR----EQRAREKE 397
           E+ ++RE    +EK R+R R KER  +++    K++  + +R+R    EQ ++EK+
Sbjct: 483 EKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQ 538



 Score = 38.1 bits (87), Expect = 0.051
 Identities = 20/63 (31%), Positives = 30/63 (47%)

Query: 335 EELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAR 394
           +E   E +R  ER R R   R     R   R + R   +E       +RELER++E++  
Sbjct: 245 KEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRL 304

Query: 395 EKE 397
           E+E
Sbjct: 305 ERE 307



 Score = 37.4 bits (85), Expect = 0.088
 Identities = 16/72 (22%), Positives = 36/72 (50%)

Query: 324 SGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERER 383
           SG       +++  +RE    +E+ R+R   +ER  +R+    K++  + +R R +  E+
Sbjct: 473 SGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQ 532

Query: 384 ELERQREQRARE 395
           E + ++ +   E
Sbjct: 533 ESQEKQHKNKDE 544



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 18/65 (27%), Positives = 40/65 (61%), Gaps = 2/65 (3%)

Query: 334 DEELRREREREREREREREADREREKERE-REREKEREQEKE-REREKERERELERQREQ 391
           D++ RR R+ +R+ ++E++  R R +ER+ R R + R   K  R R KE+  + + + ++
Sbjct: 406 DKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKE 465

Query: 392 RAREK 396
           ++ ++
Sbjct: 466 KSNKR 470



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 11/63 (17%), Positives = 35/63 (55%)

Query: 335 EELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAR 394
           + + + ++RE    +E+   R R KER  +R+    +++  + ++ R + +E++ +++  
Sbjct: 480 DSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQH 539

Query: 395 EKE 397
           + +
Sbjct: 540 KNK 542



 Score = 35.0 bits (79), Expect = 0.44
 Identities = 17/76 (22%), Positives = 34/76 (44%)

Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380
           E+ S    E  +  E+    R R+ +R+ ++E    R + RER+           +R + 
Sbjct: 391 EQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRS 450

Query: 381 RERELERQREQRAREK 396
           R +E   + +  ++EK
Sbjct: 451 RSKEKSSKHKNESKEK 466



 Score = 34.3 bits (77), Expect = 0.74
 Identities = 18/79 (22%), Positives = 34/79 (43%)

Query: 309 ELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKE 368
           E  H S +   +      S  + +  +     +E+  +R R     R    E+ ++RE  
Sbjct: 432 ERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHS 491

Query: 369 REQEKEREREKERERELER 387
             +EK R+R + +ER  +R
Sbjct: 492 PSKEKSRKRSRSKERSHKR 510



 Score = 33.9 bits (76), Expect = 0.97
 Identities = 17/76 (22%), Positives = 34/76 (44%)

Query: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKE 380
           +R    S E+    +   +E+  +R R   +      EK ++RE    +E+ ++R R KE
Sbjct: 446 KRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKE 505

Query: 381 RERELERQREQRAREK 396
           R  + +    +   +K
Sbjct: 506 RSHKRDHSDSKDQSDK 521



 Score = 31.2 bits (69), Expect = 6.3
 Identities = 26/105 (24%), Positives = 42/105 (40%), Gaps = 4/105 (3%)

Query: 335 EELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAR 394
           +E +  R R RER+    +      +R R R KE+   K +   KE+  +  R   Q  R
Sbjct: 421 KEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEK-SSKHKNESKEKSNKRSRSGSQ-GR 478

Query: 395 EKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEK 439
              +  +K  E S  P  E    R  + E   K     +  +++K
Sbjct: 479 TDSVEKSKKREHS--PSKEKSRKRSRSKERSHKRDHSDSKDQSDK 521


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.128    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,642,780
Number of Sequences: 37866
Number of extensions: 3913930
Number of successful extensions: 93243
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1071
Number of HSP's successfully gapped in prelim test: 1451
Number of HSP's that attempted gapping in prelim test: 30701
Number of HSP's gapped (non-prelim): 31730
length of query: 1217
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1103
effective length of database: 13,930,794
effective search space: 15365665782
effective search space used: 15365665782
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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