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Search of human proteins with 42741684
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
(330 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 656 0.0
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 617 e-177
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 108 7e-24
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 108 7e-24
gi|52426743 cisplatin resistance-associated overexpressed protei... 97 2e-20
gi|19923485 cisplatin resistance-associated overexpressed protei... 97 2e-20
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 92 6e-19
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 92 6e-19
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 91 2e-18
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 91 2e-18
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 91 2e-18
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 90 3e-18
gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens] 89 5e-18
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 89 7e-18
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 88 1e-17
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 86 3e-17
gi|119226260 calcium homeostasis endoplasmic reticulum protein [... 86 3e-17
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 85 1e-16
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 84 1e-16
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 84 2e-16
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 82 5e-16
gi|50962882 G patch domain containing 8 [Homo sapiens] 82 7e-16
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 80 2e-15
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 80 2e-15
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 80 3e-15
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 80 3e-15
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 80 3e-15
gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens] 79 4e-15
gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens] 79 4e-15
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 79 7e-15
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 656 bits (1693), Expect = 0.0
Identities = 330/330 (100%), Positives = 330/330 (100%)
Query: 1 MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKS 60
MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKS
Sbjct: 1 MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKS 60
Query: 61 RGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREES 120
RGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREES
Sbjct: 61 RGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREES 120
Query: 121 DGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADL 180
DGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADL
Sbjct: 121 DGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADL 180
Query: 181 SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSR 240
SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSR
Sbjct: 181 SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSR 240
Query: 241 SRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKK 300
SRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKK
Sbjct: 241 SRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKK 300
Query: 301 RRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
RRTRSRSPERRHRSSSGSSHSGSRSSSKKK
Sbjct: 301 RRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
Length = 320
Score = 617 bits (1590), Expect = e-177
Identities = 309/309 (100%), Positives = 309/309 (100%)
Query: 1 MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKS 60
MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKS
Sbjct: 1 MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKS 60
Query: 61 RGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREES 120
RGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREES
Sbjct: 61 RGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREES 120
Query: 121 DGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADL 180
DGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADL
Sbjct: 121 DGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADL 180
Query: 181 SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSR 240
SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSR
Sbjct: 181 SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSR 240
Query: 241 SRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKK 300
SRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKK
Sbjct: 241 SRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKK 300
Query: 301 RRTRSRSPE 309
RRTRSRSPE
Sbjct: 301 RRTRSRSPE 309
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 108 bits (270), Expect = 7e-24
Identities = 79/180 (43%), Positives = 100/180 (55%), Gaps = 14/180 (7%)
Query: 152 ESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSK-SRSSH 210
ES EE+D+ E K K D + SK N + + E K+ S+ RSRSK S+SS
Sbjct: 1781 ESSSEEKDDYEIFVKVK-------DTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSE 1833
Query: 211 SRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPR 270
+S R+S SRSR+R RS S S +S++RS SR R R R S+SRS SR R S S
Sbjct: 1834 HKSRKRTSE---SRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRR-SVSKE 1889
Query: 271 KRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
KR S S R RK R RSSS +RK R RSR+P RR RS + S SRS +++
Sbjct: 1890 KRKRSPKHRSKSRERK--RKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRR 1947
Score = 59.3 bits (142), Expect = 5e-09
Identities = 51/161 (31%), Positives = 71/161 (44%), Gaps = 14/161 (8%)
Query: 170 DEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRS 229
D D A ++ E S+++K + K + +H +S + + + R
Sbjct: 1760 DVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRD 1819
Query: 230 RSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSS-SSPERNRKRS 288
S S S +S+S S +SR R S+SRS +R KRS S S S R+R RS
Sbjct: 1820 SSLRSRSKRSKS---SEHKSRKRTSESRSRAR---------KRSSKSKSHRSQTRSRSRS 1867
Query: 289 RSRSSSSGDRKKRR-TRSRSPERRHRSSSGSSHSGSRSSSK 328
R R SS R K R RS S E+R RS S S R +
Sbjct: 1868 RRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKR 1908
Score = 57.4 bits (137), Expect = 2e-08
Identities = 54/192 (28%), Positives = 76/192 (39%), Gaps = 12/192 (6%)
Query: 151 KESEGEEEDEDEDLSKYKLDED-----EDEDDADLSKYNLDASEEEDSNKKKSNRRSRSK 205
KES G E++ + D ED ++ADL + L E ++ +
Sbjct: 1699 KESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPLLA 1758
Query: 206 SRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQ------SRSRSSSRERSRSRGSKSRSS 259
S RS++ S S S S + S + ++R +G K +
Sbjct: 1759 SDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKR 1818
Query: 260 SRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSS-SSGDRKKRRTRSRSPERRHRSSSGS 318
S R S K S S +R R+R RSS S R + R+RSRS RR S S S
Sbjct: 1819 DSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRS 1878
Query: 319 SHSGSRSSSKKK 330
G RS SK+K
Sbjct: 1879 KSRGRRSVSKEK 1890
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 108 bits (270), Expect = 7e-24
Identities = 79/180 (43%), Positives = 100/180 (55%), Gaps = 14/180 (7%)
Query: 152 ESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSK-SRSSH 210
ES EE+D+ E K K D + SK N + + E K+ S+ RSRSK S+SS
Sbjct: 1781 ESSSEEKDDYEIFVKVK-------DTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSE 1833
Query: 211 SRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPR 270
+S R+S SRSR+R RS S S +S++RS SR R R R S+SRS SR R S S
Sbjct: 1834 HKSRKRTSE---SRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRR-SVSKE 1889
Query: 271 KRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
KR S S R RK R RSSS +RK R RSR+P RR RS + S SRS +++
Sbjct: 1890 KRKRSPKHRSKSRERK--RKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRR 1947
Score = 59.3 bits (142), Expect = 5e-09
Identities = 51/161 (31%), Positives = 71/161 (44%), Gaps = 14/161 (8%)
Query: 170 DEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRS 229
D D A ++ E S+++K + K + +H +S + + + R
Sbjct: 1760 DVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRD 1819
Query: 230 RSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSS-SSPERNRKRS 288
S S S +S+S S +SR R S+SRS +R KRS S S S R+R RS
Sbjct: 1820 SSLRSRSKRSKS---SEHKSRKRTSESRSRAR---------KRSSKSKSHRSQTRSRSRS 1867
Query: 289 RSRSSSSGDRKKRR-TRSRSPERRHRSSSGSSHSGSRSSSK 328
R R SS R K R RS S E+R RS S S R +
Sbjct: 1868 RRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKR 1908
Score = 57.4 bits (137), Expect = 2e-08
Identities = 54/192 (28%), Positives = 76/192 (39%), Gaps = 12/192 (6%)
Query: 151 KESEGEEEDEDEDLSKYKLDED-----EDEDDADLSKYNLDASEEEDSNKKKSNRRSRSK 205
KES G E++ + D ED ++ADL + L E ++ +
Sbjct: 1699 KESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGPLLA 1758
Query: 206 SRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQ------SRSRSSSRERSRSRGSKSRSS 259
S RS++ S S S S + S + ++R +G K +
Sbjct: 1759 SDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKR 1818
Query: 260 SRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSS-SSGDRKKRRTRSRSPERRHRSSSGS 318
S R S K S S +R R+R RSS S R + R+RSRS RR S S S
Sbjct: 1819 DSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRS 1878
Query: 319 SHSGSRSSSKKK 330
G RS SK+K
Sbjct: 1879 KSRGRRSVSKEK 1890
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 97.1 bits (240), Expect = 2e-20
Identities = 66/193 (34%), Positives = 96/193 (49%), Gaps = 5/193 (2%)
Query: 132 KKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDAS--- 188
K++ G A A++ + E EE D DE L K K + +E E + + + +
Sbjct: 215 KQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRR 274
Query: 189 EEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRER 248
EEE+ K+++ R R K S SR SSR+S SRSR RSRS +SRSR R R
Sbjct: 275 EEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSR 334
Query: 249 SRSRGS-KSRSSSRSHRGSSSPRKRSYSSSSSSPERNR-KRSRSRSSSSGDRKKRRTRSR 306
S R K RS SR R S S ++SY S S +R + ++S+ + D KK +S
Sbjct: 335 SHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSG 394
Query: 307 SPERRHRSSSGSS 319
S E++ ++ S
Sbjct: 395 SREKQSEDTNTES 407
Score = 64.7 bits (156), Expect = 1e-10
Identities = 50/197 (25%), Positives = 89/197 (45%), Gaps = 12/197 (6%)
Query: 113 EYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDE----DLSKYK 168
E + + + + DE +K+K+ R + +E +++ EEE+ ++ D + K
Sbjct: 232 EKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRK 291
Query: 169 LDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS---SHSRSSSRSSSPSSSRS 225
+ S S + ++ + RRSRS+ R SH RS + S S R
Sbjct: 292 RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRR 351
Query: 226 RSRSRSRSSSSSQSRSRSSSRER-SRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERN 284
RS+SR R S +S+SR ++R S+ + + +S S S K+S +++ S E +
Sbjct: 352 RSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESD 411
Query: 285 RKRSRSRSS----SSGD 297
K + +S S GD
Sbjct: 412 TKNEVNGTSEDIKSEGD 428
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 97.1 bits (240), Expect = 2e-20
Identities = 66/193 (34%), Positives = 96/193 (49%), Gaps = 5/193 (2%)
Query: 132 KKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDAS--- 188
K++ G A A++ + E EE D DE L K K + +E E + + + +
Sbjct: 215 KQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRR 274
Query: 189 EEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRER 248
EEE+ K+++ R R K S SR SSR+S SRSR RSRS +SRSR R R
Sbjct: 275 EEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSR 334
Query: 249 SRSRGS-KSRSSSRSHRGSSSPRKRSYSSSSSSPERNR-KRSRSRSSSSGDRKKRRTRSR 306
S R K RS SR R S S ++SY S S +R + ++S+ + D KK +S
Sbjct: 335 SHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSG 394
Query: 307 SPERRHRSSSGSS 319
S E++ ++ S
Sbjct: 395 SREKQSEDTNTES 407
Score = 64.7 bits (156), Expect = 1e-10
Identities = 50/197 (25%), Positives = 89/197 (45%), Gaps = 12/197 (6%)
Query: 113 EYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDE----DLSKYK 168
E + + + + DE +K+K+ R + +E +++ EEE+ ++ D + K
Sbjct: 232 EKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRK 291
Query: 169 LDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS---SHSRSSSRSSSPSSSRS 225
+ S S + ++ + RRSRS+ R SH RS + S S R
Sbjct: 292 RSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRR 351
Query: 226 RSRSRSRSSSSSQSRSRSSSRER-SRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERN 284
RS+SR R S +S+SR ++R S+ + + +S S S K+S +++ S E +
Sbjct: 352 RSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESD 411
Query: 285 RKRSRSRSS----SSGD 297
K + +S S GD
Sbjct: 412 TKNEVNGTSEDIKSEGD 428
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 92.0 bits (227), Expect = 6e-19
Identities = 84/249 (33%), Positives = 110/249 (44%), Gaps = 44/249 (17%)
Query: 118 EESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDD 177
+E + K++ +RG S E S+ ++ D S+ + +
Sbjct: 361 KERSHSHSRSSSKERDHRG------SSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRS 414
Query: 178 ADLSKYNL-DASEEEDSNKKKSNRRSRS--------KSRSSH-SRSSSRSSSPSSSRSRS 227
S Y D S NK + RSRS +SRS + +R SRS SP+ +R RS
Sbjct: 415 RSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRS 474
Query: 228 RSRSRSSSSSQS------------RSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYS 275
RSRS S S RSRS S+ER + R S+S S R HR S SP K
Sbjct: 475 RSRSPSKERDHSQLGSPSKERDHRRSRSPSKER-QCRQSRSSSKERDHRRSRSPSKERQR 533
Query: 276 SSSSSPERNRKRSRSRS-----------SSSGDRKKRRTRSRSPERRHRSSSGSS----H 320
S SP + R RS+SRS S S +R +RR RS S ER R S SS H
Sbjct: 534 RQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDH 593
Query: 321 SGSRSSSKK 329
S SRS +K+
Sbjct: 594 SRSRSPNKQ 602
Score = 85.1 bits (209), Expect = 8e-17
Identities = 80/264 (30%), Positives = 109/264 (41%), Gaps = 46/264 (17%)
Query: 90 TPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVE 149
TP AK + TG +E+SD RK K Y G+ + P+
Sbjct: 213 TPSTAKCQTPTGIPS------------KEKSDNPSPSSSRKVKSY-GQMIIPS------- 252
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
+E + + Y + + S + S RS S R+
Sbjct: 253 -REKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRN- 310
Query: 210 HSRSSSRSS----SPSSSRSRSRSRSRSSSSSQSR----------SRSSSRERSRSRGSK 255
HSR+ SR+ S S+SRS S+ S +QSR SR+ S+ERS S S+
Sbjct: 311 HSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSH-SR 369
Query: 256 SRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKR---------RTRSR 306
S S R HRGSSSPRK S S S SP + R SRSRS + + R R+RSR
Sbjct: 370 SSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSR 429
Query: 307 SPERRHRSSSGSSHSGSRSSSKKK 330
SP + S S +R S+ +
Sbjct: 430 SPNKARDCSRSRSPYKARDRSRSR 453
Score = 84.7 bits (208), Expect = 1e-16
Identities = 67/172 (38%), Positives = 88/172 (51%), Gaps = 28/172 (16%)
Query: 187 ASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSS- 245
+ E S+ + S++ + SS + S RS S S ++ R SRSRS + ++ RSRS S
Sbjct: 360 SKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSP 419
Query: 246 ---RERSRSRG-------SKSRS--SSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRS- 292
R+RSRSR S+SRS +R S SP K S S SP + R RSRSRS
Sbjct: 420 YKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSP 479
Query: 293 ----------SSSGDRKKRRTRSRSPERRHRSSSGSS----HSGSRSSSKKK 330
S S +R RR+RS S ER+ R S SS H SRS SK++
Sbjct: 480 SKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKER 531
Score = 84.3 bits (207), Expect = 1e-16
Identities = 61/150 (40%), Positives = 80/150 (53%), Gaps = 13/150 (8%)
Query: 186 DASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSS 245
D S+ +K++ +RRSRS S+ R S RSSS RSRS S+ QSRS +
Sbjct: 484 DHSQLGSPSKERDHRRSRSPSKERQCRQS-RSSSKERDHRRSRSPSKERQRRQSRSPNKE 542
Query: 246 RERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRS 305
R+RS+SR S S R HR S SP K SP + R+R +SRSSS ++ +RS
Sbjct: 543 RDRSQSR---SPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSE---ERDHSRS 596
Query: 306 RSP------ERRHRSSSGSSHSGSRSSSKK 329
RSP R SS +HS SR+ SK+
Sbjct: 597 RSPNKQSGYSRPRASSKEKAHSRSRTPSKE 626
Score = 77.8 bits (190), Expect = 1e-14
Identities = 55/141 (39%), Positives = 77/141 (54%), Gaps = 13/141 (9%)
Query: 189 EEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRER 248
+ S+K++ +RRSRS S+ R +S SP+ R RS+SRS S +SRS S+ER
Sbjct: 511 QSRSSSKERDHRRSRSPSKERQRR---QSRSPNKERDRSQSRSPSEEREHRQSRSPSKER 567
Query: 249 SRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSP 308
R R +S S R R S S + S S SP + SR R+SS ++K +RSR+P
Sbjct: 568 DRRRW-RSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASS---KEKAHSRSRTP 623
Query: 309 ERRHRSSSGSSHSGSRSSSKK 329
S +HS SR+SSK+
Sbjct: 624 ------SKEGNHSQSRTSSKE 638
Score = 72.8 bits (177), Expect = 4e-13
Identities = 53/178 (29%), Positives = 84/178 (47%), Gaps = 5/178 (2%)
Query: 146 KEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSK 205
KE + ++S ++ D S+ E + +K D S+ ++++ +R+SRS
Sbjct: 505 KERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKER-DRSQSRSPSEEREHRQSRSP 563
Query: 206 SRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRG 265
S+ R R SPS R R +SRS S SRSRS +++ SR ++ S ++H
Sbjct: 564 SKE---RDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSR-PRASSKEKAHSR 619
Query: 266 SSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGS 323
S +P K S S + + S+S S D K+ TR+ S + S SSHS S
Sbjct: 620 SRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPS 677
Score = 71.6 bits (174), Expect = 9e-13
Identities = 68/218 (31%), Positives = 92/218 (42%), Gaps = 13/218 (5%)
Query: 117 REESDGEYDEFGRKKKKYR---GKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDE 173
RE SD + KK YR G +G +S E+ S + + SK K D
Sbjct: 181 RERSDSQPRNLS--KKSYRPPGGSGIGRSS---ELAVTPSTAKCQTPTGIPSKEKSDNPS 235
Query: 174 DEDDADLSKYN---LDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSR 230
+ Y + + E+ S + S+R S+ SR S S S S RSRS S+
Sbjct: 236 PSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQ 295
Query: 231 SRSSSSSQSRSRSSSRERSRSRGSKSRSSSRS-HRGSSSPRKRSYSSSSSSPERNRKRSR 289
R+ S +S S + R+RSR K S H S S K + S +P R R +
Sbjct: 296 KRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNW 355
Query: 290 SRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
SR+ S +R +RS S ER HR SS RS S
Sbjct: 356 SRNPSK-ERSHSHSRSSSKERDHRGSSSPRKESGRSQS 392
Score = 70.9 bits (172), Expect = 2e-12
Identities = 66/178 (37%), Positives = 85/178 (47%), Gaps = 35/178 (19%)
Query: 188 SEEEDSNKKKSNRRSRSKSRS-SHSRSSSRSSSPSSSRSRSRSRSR----------SSSS 236
S+ +K KS +SR+ R SH+ S + S S S SRS S+ R S
Sbjct: 330 SQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGR 389
Query: 237 SQSRSRSSSRERSRSRG-------SKSRS--SSRSHRGSSSPRKRSYSSSSSSPERNRKR 287
SQS S + R+ SRSR S+SRS +R S SP K S S SP + R R
Sbjct: 390 SQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDR 449
Query: 288 SRSRS---------SSSGDRKKRRTRSRSPER-RHRSSSGS-----SHSGSRSSSKKK 330
SRSRS S S ++ + R+RSRSP + R S GS H SRS SK++
Sbjct: 450 SRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKER 507
Score = 67.4 bits (163), Expect = 2e-11
Identities = 65/213 (30%), Positives = 95/213 (44%), Gaps = 26/213 (12%)
Query: 131 KKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEE 190
K + R ++ P+ KE + + ++ D S+ E + SK D
Sbjct: 469 KARDRSRSRSPS---KERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKER-DHRRS 524
Query: 191 EDSNKKKSNRRSRSKSRS---SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRE 247
+K++ R+SRS ++ S SRS S SRS S+ R R R RS S+E
Sbjct: 525 RSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDR------RRWRSPSKE 578
Query: 248 RSRSRGSKSRSSSRSHRGSSSPRKRS-YS-----------SSSSSPERNRKRSRSRSSSS 295
R R R S+S S R H S SP K+S YS S S +P + S+SR+SS
Sbjct: 579 RER-RQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSK 637
Query: 296 GDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSK 328
+ T RSP+ + + SS S +R+ SK
Sbjct: 638 ESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSK 670
Score = 65.9 bits (159), Expect = 5e-11
Identities = 55/190 (28%), Positives = 84/190 (44%), Gaps = 17/190 (8%)
Query: 146 KEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSK 205
KE + ++S ++ D S+ +E E SK D +K++ R+SRS
Sbjct: 529 KERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKER-DRRRWRSPSKERERRQSRS- 586
Query: 206 SRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSS----- 260
SS R SRS SP+ SR R+ S + SRSR+ S+E + S+ S S
Sbjct: 587 --SSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQS 644
Query: 261 ---RSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSG 317
RS SP + S S + +P + S S S G +T S+ + ++S
Sbjct: 645 TVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGG-----QTLSQDDSQADATTSK 699
Query: 318 SSHSGSRSSS 327
++ G RSSS
Sbjct: 700 ATLPGERSSS 709
Score = 55.5 bits (132), Expect = 7e-08
Identities = 40/130 (30%), Positives = 69/130 (53%), Gaps = 5/130 (3%)
Query: 202 SRSKSRSSHSRSSSRS-SSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSS 260
S S S+S+ S S+ R+ S+ SSRSR RS++R+ S + +R+S + S++ +
Sbjct: 58 SPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTS--KASKASDVRCHQRR 115
Query: 261 RSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSH 320
+H +P +R SS SP R R R + G R +R R+P + + S G S+
Sbjct: 116 GTHSRGRTPGRRGSRSSKRSPSRASTPGRIR--THGARPGMASRVRTPTSQQKGSRGKSY 173
Query: 321 SGSRSSSKKK 330
R+S++++
Sbjct: 174 GRPRTSNRER 183
Score = 55.5 bits (132), Expect = 7e-08
Identities = 66/200 (33%), Positives = 93/200 (46%), Gaps = 57/200 (28%)
Query: 184 NLDASEEEDSNKKKSNRRSRSKS---RSSH-----------------SRSSSRSSSPSSS 223
N + S+ + N K + R S RSS S+ S + SPSSS
Sbjct: 180 NRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSS 239
Query: 224 R-----------SRSRSRSRSSSSSQSRSRSSSRERSRSRG-SKSRSSSRSHRGSSSPRK 271
R SR +S S + SS+ +S + + RSR + S+SRS RS GS +K
Sbjct: 240 RKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGS---QK 296
Query: 272 RSYSS-SSSSPERNRKRSRSRS-------------SSSGDRKKRRTRSRSPERRHRSSSG 317
R++S S S +RN R+RSR+ S S + K + +SR+P RR RS +
Sbjct: 297 RTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTP-RRGRSHNW 355
Query: 318 S-------SHSGSRSSSKKK 330
S SHS SRSSSK++
Sbjct: 356 SRNPSKERSHSHSRSSSKER 375
Score = 48.9 bits (115), Expect = 6e-06
Identities = 44/140 (31%), Positives = 74/140 (52%), Gaps = 5/140 (3%)
Query: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRS-RSRSRSRS-SSSSQSRSRSSSRERSR 250
S+ K+S++ S S + S S ++ P+S +S +S + +RS + + SR+S S
Sbjct: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61
Query: 251 SRGSKSRSSSR--SHRGSSSPRKRSYSSSSSSPERNRKRSR-SRSSSSGDRKKRRTRSRS 307
S+ +KS S+ R S+R SS R RS + + S + + S+ S++S ++R T SR
Sbjct: 62 SKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRG 121
Query: 308 PERRHRSSSGSSHSGSRSSS 327
R S S S SR+S+
Sbjct: 122 RTPGRRGSRSSKRSPSRAST 141
Score = 44.7 bits (104), Expect = 1e-04
Identities = 45/179 (25%), Positives = 73/179 (40%), Gaps = 41/179 (22%)
Query: 193 SNKKKSNRRS---RSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERS 249
S+K+ +R S R ++ + +SR +P+S + SR +S + +R RS S+ R+
Sbjct: 131 SSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRN 190
Query: 250 RSR------------------------------GSKSRSSSRSHRGSSSPRKRSYS---- 275
S+ G S+ S + SSS + +SY
Sbjct: 191 LSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMII 250
Query: 276 ---SSSSSPERNRKRSRS-RSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
S SP R +S +S+ R + ++SRSP R S +HS RS S K+
Sbjct: 251 PSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKR 309
Score = 43.9 bits (102), Expect = 2e-04
Identities = 40/130 (30%), Positives = 64/130 (49%), Gaps = 16/130 (12%)
Query: 187 ASEEEDSNKKKSNRRSRSKSR-----SSHSRSSSRSSSP---------SSSRSRSRSRSR 232
+++ SN+ S R RSK+R S+ +R+S S + + SR R+ R
Sbjct: 69 STKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRG 128
Query: 233 SSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPE-RNRKRSRSR 291
S SS +S SR+S+ R R+ G++ +SR R +S +K S S P NR+RS S+
Sbjct: 129 SRSSKRSPSRASTPGRIRTHGARPGMASRV-RTPTSQQKGSRGKSYGRPRTSNRERSDSQ 187
Query: 292 SSSSGDRKKR 301
+ + R
Sbjct: 188 PRNLSKKSYR 197
Score = 41.2 bits (95), Expect = 0.001
Identities = 38/134 (28%), Positives = 64/134 (47%), Gaps = 12/134 (8%)
Query: 203 RSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRS 262
+ S+ S S + S SS P++ S + S++ +RS ++ + S SSS+S
Sbjct: 5 KRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKS 64
Query: 263 HRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRS------RSPERRHRSSS 316
+ +S+ R S SS R+R RS++R+ S R +++ R +RR S
Sbjct: 65 TKSTSTKRAPSNRPSS----RSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSR 120
Query: 317 GSS--HSGSRSSSK 328
G + GSRSS +
Sbjct: 121 GRTPGRRGSRSSKR 134
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 92.0 bits (227), Expect = 6e-19
Identities = 68/161 (42%), Positives = 86/161 (53%), Gaps = 18/161 (11%)
Query: 158 EDEDEDLSKYKLDEDED-EDDADLSKYNLDASEE-EDSNKKKSNRRSRSKSRSSHSRSSS 215
E +D+ K+K +E D E +D + L++SE ED +K+K + SR + SHSRS S
Sbjct: 15 ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR---SHSRSRS 71
Query: 216 RSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYS 275
R R RSRSR R S S+SR R SR RSR R KSRS SR RKR
Sbjct: 72 R-----ERRHRSRSRERKKSRSRSRERKKSRSRSRER-KKSRSRSRE-------RKRRIR 118
Query: 276 SSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSS 316
S S S R+R R+RSRS + + R+ R P R RS S
Sbjct: 119 SRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLS 159
Score = 81.6 bits (200), Expect = 9e-16
Identities = 51/138 (36%), Positives = 70/138 (50%), Gaps = 4/138 (2%)
Query: 197 KSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRG-SK 255
K RR SK +SS S + S + R R SS + + R + R+ SR R S+
Sbjct: 9 KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
Query: 256 SRSSSRSHRGSSSPRKRSYSSS---SSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRH 312
SRS R HR S RK+S S S S R+R+R +SRS S +++ R+RSRS R
Sbjct: 69 SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR 128
Query: 313 RSSSGSSHSGSRSSSKKK 330
+ S + SRS +KK
Sbjct: 129 HRTRSRSRTRSRSRDRKK 146
Score = 71.6 bits (174), Expect = 9e-13
Identities = 56/168 (33%), Positives = 81/168 (48%), Gaps = 12/168 (7%)
Query: 146 KEVEDKESEGEEEDEDE---DLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRS 202
K+ K+ + EE ++ E D + +L+ E+ +D K + S + RR
Sbjct: 17 KDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRH 76
Query: 203 RSKSRS-SHSRSSSRSSSPSSSRSRSRSRSRSSS-------SSQSRSRSSSRERSRSRGS 254
RS+SR SRS SR S SRSR R +SRS S S+SRSRS R R+RSR S
Sbjct: 77 RSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSR-S 135
Query: 255 KSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRR 302
++RS SR + +R S S +P R R+ + + + RR
Sbjct: 136 RTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARR 183
Score = 49.7 bits (117), Expect = 4e-06
Identities = 40/157 (25%), Positives = 61/157 (38%), Gaps = 5/157 (3%)
Query: 146 KEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSK 205
K E K S G + + + S +KKS RSR +
Sbjct: 54 KRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER 113
Query: 206 SRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRG 265
R SRS SRS +RSRSR+RSR S+ R + + R SR S RG
Sbjct: 114 KRRIRSRSRSRSRHRHRTRSRSRTRSR----SRDRKKRIEKPRRFSRSLSRTPSPPPFRG 169
Query: 266 SSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRR 302
++ + + + ER +K R +++K++
Sbjct: 170 RNTAMD-AQEALARRLERAKKLQEQREKEMVEKQKQQ 205
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 90.5 bits (223), Expect = 2e-18
Identities = 72/225 (32%), Positives = 112/225 (49%), Gaps = 23/225 (10%)
Query: 89 NTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEV 148
+T + K +ER ERE + E+E+ G+ + ++++K R K +
Sbjct: 379 DTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREK--------DKE 430
Query: 149 EDKESEGEEEDE-DEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSR 207
+D+E E E+E E D D K K + E E + D SK E K+K +++SR+ R
Sbjct: 431 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK--------EIDEKRKKDKKSRTPPR 482
Query: 208 SSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRE---RSRSRGSKSRSSSRSHR 264
S ++ SRSSS R RSRS SRS +S++ R SSR RSR++ K R R H
Sbjct: 483 SYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHI 542
Query: 265 GSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPE 309
R+RS S SS +R+ K ++S+S K + ++ P+
Sbjct: 543 SERRERERSTSMRKSSNDRDGKEKLEKNSTS---LKEKEHNKEPD 584
Score = 81.3 bits (199), Expect = 1e-15
Identities = 72/225 (32%), Positives = 106/225 (47%), Gaps = 36/225 (16%)
Query: 108 ERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKY 167
E+E V+ +RE+ E R+K+K RGK +D++ E E+D ++D K
Sbjct: 386 EKERVKEKDREKEREREKE--REKEKERGKN----------KDRDKE-REKDREKDKEKD 432
Query: 168 KLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRS 227
+ E E E + D K +E++ +K+K + RSK + +S +P S + S
Sbjct: 433 REREREKEHEKDRDK-----EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNAS 487
Query: 228 RSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKR 287
R RSRSSSRER R R SRSSSRS R S + +++ SS S SP K+
Sbjct: 488 R-----------RSRSSSRERRRRR---SRSSSRSPRTSKTIKRK--SSRSPSPRSRNKK 531
Query: 288 SRSRSSSSGDRKKRRTRSRSPERRHRSS--SGSSHSGSRSSSKKK 330
+ R +RR R RS R S+ G S+S K+
Sbjct: 532 DKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKE 576
Score = 74.3 bits (181), Expect = 1e-13
Identities = 51/156 (32%), Positives = 73/156 (46%), Gaps = 14/156 (8%)
Query: 189 EEEDSNKKKSNR---RSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSS 245
E SN++K R +RSKSRSS S R S S RSRS +RSRS + RS+S
Sbjct: 296 ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPH 355
Query: 246 RERSRS---RGSKSRSSSRSHRGSSSPR---KRSYSSSSSSPERNRKRSRSRSSSSG--- 296
++RS+S R S+SRS SR R + + K ER R++ R + G
Sbjct: 356 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 415
Query: 297 --DRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
D+++ + R + E+ H R K+K
Sbjct: 416 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEK 451
Score = 70.1 bits (170), Expect = 3e-12
Identities = 56/149 (37%), Positives = 75/149 (50%), Gaps = 13/149 (8%)
Query: 185 LDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSR---SRSRSRSRSSSSSQSRS 241
+ A+ E +S K SN R +SRS H+RS SRSSS S SR S+S+ RSR S ++SRS
Sbjct: 289 ISAAIEPESGK--SNERKGGRSRS-HTRSKSRSSSKSHSRRKRSQSKHRSR--SHNRSRS 343
Query: 242 RSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKR 301
R R RS+S K RS SR R S R RS+S R + + + R DR+K
Sbjct: 344 RQKDRRRSKS-PHKKRSKSRERRKS---RSRSHSRDKRKDTREKIKEKERVKEK-DREKE 398
Query: 302 RTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
R R + E+ R ++K
Sbjct: 399 REREKEREKEKERGKNKDRDKEREKDREK 427
Score = 69.3 bits (168), Expect = 4e-12
Identities = 59/223 (26%), Positives = 101/223 (45%), Gaps = 16/223 (7%)
Query: 117 REESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDED 176
R +S + R+++K R ++ K+ +K E +E +++D K + E E E
Sbjct: 350 RSKSPHKKRSKSRERRKSRSRSHSRDK-RKDTREKIKE-KERVKEKDREKEREREKEREK 407
Query: 177 DADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS-HSRSSSRSSSPSSSRSRSRSRSRSSS 235
+ + K N D +E + +++K + R + R H + + + + R + RS
Sbjct: 408 EKERGK-NKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKE 466
Query: 236 SSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPER-----NRKRSRS 290
+ R + ++SR+ +S ++SR R SS R+R S SSS R RK SRS
Sbjct: 467 IDEKRKKD---KKSRTP-PRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 522
Query: 291 ---RSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
RS + D+K+ + R ERR R S S S K+
Sbjct: 523 PSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKE 565
Score = 68.6 bits (166), Expect = 8e-12
Identities = 50/147 (34%), Positives = 72/147 (48%), Gaps = 10/147 (6%)
Query: 187 ASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQS---RSRS 243
A+ +E K R ++S ++ S +S+ RSRS +RS+S SSS+S R RS
Sbjct: 270 AAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRS 329
Query: 244 SSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRT 303
S+ RSRS ++SRS + R S SP K+ S R R++SRSRS S RK R
Sbjct: 330 QSKHRSRSH-NRSRSRQKDRRRSKSPHKK------RSKSRERRKSRSRSHSRDKRKDTRE 382
Query: 304 RSRSPERRHRSSSGSSHSGSRSSSKKK 330
+ + ER + K+K
Sbjct: 383 KIKEKERVKEKDREKEREREKEREKEK 409
Score = 60.5 bits (145), Expect = 2e-09
Identities = 49/240 (20%), Positives = 85/240 (35%), Gaps = 17/240 (7%)
Query: 91 PKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVED 150
P+ K ER G + R + S + R + K+R ++
Sbjct: 295 PESGKSNERKGGRSRSHTRS-----KSRSSSKSHSRRKRSQSKHRSRS-----------H 338
Query: 151 KESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSH 210
S ++D S +K E S+ + ++ K K R + K R
Sbjct: 339 NRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKE 398
Query: 211 SRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPR 270
R + R +++ R + + + + RER R + + + +
Sbjct: 399 -REREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEK 457
Query: 271 KRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
+R S E+ +K +SR+ RR+RS S ERR R S SS S S + K+
Sbjct: 458 EREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKR 517
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 90.5 bits (223), Expect = 2e-18
Identities = 72/225 (32%), Positives = 112/225 (49%), Gaps = 23/225 (10%)
Query: 89 NTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEV 148
+T + K +ER ERE + E+E+ G+ + ++++K R K +
Sbjct: 263 DTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREK--------DKE 314
Query: 149 EDKESEGEEEDE-DEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSR 207
+D+E E E+E E D D K K + E E + D SK E K+K +++SR+ R
Sbjct: 315 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK--------EIDEKRKKDKKSRTPPR 366
Query: 208 SSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRE---RSRSRGSKSRSSSRSHR 264
S ++ SRSSS R RSRS SRS +S++ R SSR RSR++ K R R H
Sbjct: 367 SYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHI 426
Query: 265 GSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPE 309
R+RS S SS +R+ K ++S+S K + ++ P+
Sbjct: 427 SERRERERSTSMRKSSNDRDGKEKLEKNSTS---LKEKEHNKEPD 468
Score = 81.3 bits (199), Expect = 1e-15
Identities = 72/225 (32%), Positives = 106/225 (47%), Gaps = 36/225 (16%)
Query: 108 ERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKY 167
E+E V+ +RE+ E R+K+K RGK +D++ E E+D ++D K
Sbjct: 270 EKERVKEKDREKEREREKE--REKEKERGKN----------KDRDKE-REKDREKDKEKD 316
Query: 168 KLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRS 227
+ E E E + D K +E++ +K+K + RSK + +S +P S + S
Sbjct: 317 REREREKEHEKDRDK-----EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNAS 371
Query: 228 RSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKR 287
R RSRSSSRER R R SRSSSRS R S + +++ SS S SP K+
Sbjct: 372 R-----------RSRSSSRERRRRR---SRSSSRSPRTSKTIKRK--SSRSPSPRSRNKK 415
Query: 288 SRSRSSSSGDRKKRRTRSRSPERRHRSS--SGSSHSGSRSSSKKK 330
+ R +RR R RS R S+ G S+S K+
Sbjct: 416 DKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKE 460
Score = 74.3 bits (181), Expect = 1e-13
Identities = 51/156 (32%), Positives = 73/156 (46%), Gaps = 14/156 (8%)
Query: 189 EEEDSNKKKSNR---RSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSS 245
E SN++K R +RSKSRSS S R S S RSRS +RSRS + RS+S
Sbjct: 180 ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPH 239
Query: 246 RERSRS---RGSKSRSSSRSHRGSSSPR---KRSYSSSSSSPERNRKRSRSRSSSSG--- 296
++RS+S R S+SRS SR R + + K ER R++ R + G
Sbjct: 240 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 299
Query: 297 --DRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
D+++ + R + E+ H R K+K
Sbjct: 300 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEK 335
Score = 70.1 bits (170), Expect = 3e-12
Identities = 56/149 (37%), Positives = 75/149 (50%), Gaps = 13/149 (8%)
Query: 185 LDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSR---SRSRSRSRSSSSSQSRS 241
+ A+ E +S K SN R +SRS H+RS SRSSS S SR S+S+ RSR S ++SRS
Sbjct: 173 ISAAIEPESGK--SNERKGGRSRS-HTRSKSRSSSKSHSRRKRSQSKHRSR--SHNRSRS 227
Query: 242 RSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKR 301
R R RS+S K RS SR R S R RS+S R + + + R DR+K
Sbjct: 228 RQKDRRRSKS-PHKKRSKSRERRKS---RSRSHSRDKRKDTREKIKEKERVKEK-DREKE 282
Query: 302 RTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
R R + E+ R ++K
Sbjct: 283 REREKEREKEKERGKNKDRDKEREKDREK 311
Score = 69.3 bits (168), Expect = 4e-12
Identities = 59/223 (26%), Positives = 101/223 (45%), Gaps = 16/223 (7%)
Query: 117 REESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDED 176
R +S + R+++K R ++ K+ +K E +E +++D K + E E E
Sbjct: 234 RSKSPHKKRSKSRERRKSRSRSHSRDK-RKDTREKIKE-KERVKEKDREKEREREKEREK 291
Query: 177 DADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS-HSRSSSRSSSPSSSRSRSRSRSRSSS 235
+ + K N D +E + +++K + R + R H + + + + R + RS
Sbjct: 292 EKERGK-NKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKE 350
Query: 236 SSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPER-----NRKRSRS 290
+ R + ++SR+ +S ++SR R SS R+R S SSS R RK SRS
Sbjct: 351 IDEKRKKD---KKSRTP-PRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 406
Query: 291 ---RSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
RS + D+K+ + R ERR R S S S K+
Sbjct: 407 PSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKE 449
Score = 68.6 bits (166), Expect = 8e-12
Identities = 50/147 (34%), Positives = 72/147 (48%), Gaps = 10/147 (6%)
Query: 187 ASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQS---RSRS 243
A+ +E K R ++S ++ S +S+ RSRS +RS+S SSS+S R RS
Sbjct: 154 AAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRS 213
Query: 244 SSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRT 303
S+ RSRS ++SRS + R S SP K+ S R R++SRSRS S RK R
Sbjct: 214 QSKHRSRSH-NRSRSRQKDRRRSKSPHKK------RSKSRERRKSRSRSHSRDKRKDTRE 266
Query: 304 RSRSPERRHRSSSGSSHSGSRSSSKKK 330
+ + ER + K+K
Sbjct: 267 KIKEKERVKEKDREKEREREKEREKEK 293
Score = 60.5 bits (145), Expect = 2e-09
Identities = 49/240 (20%), Positives = 85/240 (35%), Gaps = 17/240 (7%)
Query: 91 PKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVED 150
P+ K ER G + R + S + R + K+R ++
Sbjct: 179 PESGKSNERKGGRSRSHTRS-----KSRSSSKSHSRRKRSQSKHRSRS-----------H 222
Query: 151 KESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSH 210
S ++D S +K E S+ + ++ K K R + K R
Sbjct: 223 NRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKE 282
Query: 211 SRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPR 270
R + R +++ R + + + + RER R + + + +
Sbjct: 283 -REREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEK 341
Query: 271 KRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
+R S E+ +K +SR+ RR+RS S ERR R S SS S S + K+
Sbjct: 342 EREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKR 401
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 90.5 bits (223), Expect = 2e-18
Identities = 75/172 (43%), Positives = 91/172 (52%), Gaps = 25/172 (14%)
Query: 151 KESEGEE-EDEDEDLSKYKLDEDED-EDDADLSKYNLDASEE-EDSNKKKSNRRSRSKSR 207
+ EG E +D+ K+K +E D E +D + L++SE ED +K+K + SR +S
Sbjct: 66 RSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS- 124
Query: 208 SSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSS 267
HSRS SR R RSRSR R S S+SR R SR RSR R KSRS SR
Sbjct: 125 --HSRSRSRER-----RHRSRSRERKKSRSRSRERKKSRSRSRER-KKSRSRSRE----- 171
Query: 268 SPRKRSYSSSSSSPERNRKRSRSRS---SSSGDRKKRRTRSRSPERRHRSSS 316
RKR S S S R+R R+RSRS S S DRKK R P R RS S
Sbjct: 172 --RKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKK---RIEKPRRFSRSLS 218
Score = 88.6 bits (218), Expect = 7e-18
Identities = 64/187 (34%), Positives = 86/187 (45%), Gaps = 8/187 (4%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
DK+ E E SK+ K + + + ++ K RR SK +SS
Sbjct: 21 DKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSS 80
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRG-SKSRSSSRSHRGSSS 268
S + S + R R SS + + R + R+ SR R S+SRS R HR S
Sbjct: 81 KKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSR 140
Query: 269 PRKRSYSSS-----SSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGS 323
RK+S S S S S R RK+SRSRS R + R+RSRS RHR+ S S + S
Sbjct: 141 ERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRS-RHRHRTRS-RSRTRS 198
Query: 324 RSSSKKK 330
RS +KK
Sbjct: 199 RSRDRKK 205
Score = 75.5 bits (184), Expect = 6e-14
Identities = 61/189 (32%), Positives = 87/189 (46%), Gaps = 12/189 (6%)
Query: 125 DEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDE---DLSKYKLDEDEDEDDADLS 181
D GRK + G K+ K+ + EE ++ E D + +L+ E+ +D
Sbjct: 55 DNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKR 114
Query: 182 KYNLDASEEEDSNKKKSNRRSRSKSRS---SHSRSSSRSSSPSSSRSRSRSRSRSSS--- 235
K + S + RR RS+SR S SRS R S S SR R +SRSRS
Sbjct: 115 KERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR 174
Query: 236 --SSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSS 293
S+SRSRS R R+RSR S++RS SR + +R S S +P R R+ +
Sbjct: 175 RIRSRSRSRSRHRHRTRSR-SRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAM 233
Query: 294 SSGDRKKRR 302
+ + RR
Sbjct: 234 DAQEALARR 242
Score = 74.7 bits (182), Expect = 1e-13
Identities = 53/174 (30%), Positives = 78/174 (44%), Gaps = 12/174 (6%)
Query: 163 DLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSS 222
D + L ++ D D K + SE S + + SRS+SRS R R S
Sbjct: 5 DTERDGLAPEKTSPDRDKKK---EQSEVSVSPRASKHHYSRSRSRS---RERKRKSDNEG 58
Query: 223 SRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSR------SHRGSSSPRKRSYSS 276
+ RSRSRS+ +S+ +SS + +S K SS + S KR
Sbjct: 59 RKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERK 118
Query: 277 SSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
SS +R RSR R S R+++++RSRS ER+ S SRS S+++
Sbjct: 119 SSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER 172
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 89.7 bits (221), Expect = 3e-18
Identities = 75/189 (39%), Positives = 96/189 (50%), Gaps = 17/189 (8%)
Query: 145 LKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRS 204
LK+ + E D ++ + + E D + LD +E N R
Sbjct: 126 LKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNI----RLIED 181
Query: 205 KSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHR 264
K R+SH RS S S S S SR RSRSRSR SS S+SRS S SR RSRSR SK RS SR
Sbjct: 182 KPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSR-SKGRSRSR--- 237
Query: 265 GSSSPRKRSYSSSSSSPERNR---KRSRSRSSSSGDRKKRRTRSRSPERRHR---SSSGS 318
S ++S S S S P+ +R SRSRS ++ + R+RSRSP+ + S
Sbjct: 238 ---SKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSR 294
Query: 319 SHSGSRSSS 327
S S SRS+S
Sbjct: 295 SRSQSRSNS 303
Score = 86.3 bits (212), Expect = 3e-17
Identities = 64/145 (44%), Positives = 83/145 (57%), Gaps = 9/145 (6%)
Query: 194 NKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSR-SRSSSRERSRS- 251
++ +S RRSRS+SR S SRS SRS S S SRSRSRS+ RS S S+ R SRS S+ + +S
Sbjct: 196 SRSRSRRRSRSRSRRS-SRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSD 254
Query: 252 RGSKSRSSSRSHRGSSSPRKRSYSSSSSS------PERNRKRSRSRSSSSGDRKKRRTRS 305
RGS S S SRS R RS S S ++R RS+SRS+S + RS
Sbjct: 255 RGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARS 314
Query: 306 RSPERRHRSSSGSSHSGSRSSSKKK 330
SP + +S S S S+S S+ +
Sbjct: 315 VSPPPKRATSRSRSRSRSKSRSRSR 339
Score = 80.5 bits (197), Expect = 2e-15
Identities = 78/208 (37%), Positives = 99/208 (47%), Gaps = 48/208 (23%)
Query: 149 EDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS 208
+++ +EG E K LD+ D +++ N+ E++ + S+RRS S SRS
Sbjct: 143 KERTNEGVIEFRSYSDMKRALDK---LDGTEINGRNIRLIEDKP---RTSHRRSYSGSRS 196
Query: 209 SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSS 268
SRS RS S S SRSRSRS S S S+SRSRS R RSRS+G KSRS S+S + S
Sbjct: 197 -RSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKS-KPKSD 254
Query: 269 PRKRSYSSSSSSPERNRKRSRSRSSS-----SGDRKKR---------------------- 301
S+S S S E + RSRSRS S GD K +
Sbjct: 255 RGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARS 314
Query: 302 ------------RTRSRSPER-RHRSSS 316
R+RSRS R R RSSS
Sbjct: 315 VSPPPKRATSRSRSRSRSKSRSRSRSSS 342
Score = 72.4 bits (176), Expect = 5e-13
Identities = 78/249 (31%), Positives = 102/249 (40%), Gaps = 45/249 (18%)
Query: 83 SECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPA 142
S C+ + + + Y ER N IE Y + R K G +
Sbjct: 119 SRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRS----YSDMKRALDKLDGTEINGR 174
Query: 143 SILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRS 202
+I + +EDK S+ + + S +S RS
Sbjct: 175 NI-RLIEDKPRTSHRRSYSGSRSRSR---------------SRRRSRSRSRRSSRSRSRS 218
Query: 203 RSKSRS-SHSRSSSRSSSPSS---SRSRSRSRSRSSSSSQSRSRSSSR---ERSRSRGSK 255
SKSRS S SRS RS S S SRS+S+S+ +S S S SRS S+ E+SRSR S+
Sbjct: 219 ISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSR-SR 277
Query: 256 SRSSSRSHRGSSSPRKRSYSSSSS--------------SPERNRKRSRSRSSSSGDRKKR 301
SRS + +G + RS S S S SP R SRSRS S R K
Sbjct: 278 SRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRS---RSKS 334
Query: 302 RTRSRSPER 310
R+RSRS R
Sbjct: 335 RSRSRSSSR 343
Score = 60.5 bits (145), Expect = 2e-09
Identities = 56/153 (36%), Positives = 74/153 (48%), Gaps = 14/153 (9%)
Query: 179 DLSKYNLDASEEE--DSNKKKSNRRS-RSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS 235
DL + A E D++K+++N +S S R+ + + R
Sbjct: 125 DLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPR 184
Query: 236 SSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSS 295
+S RS S SR RSRSR RS SRS R S S R RS S S S R+R RS+ RS S
Sbjct: 185 TSHRRSYSGSRSRSRSR---RRSRSRSRRSSRS-RSRSISKSRS---RSRSRSKGRSRSR 237
Query: 296 GDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSK 328
+K R++S+S + R SHS SRS SK
Sbjct: 238 SKGRKSRSKSKSKPKSDR----GSHSHSRSRSK 266
Score = 58.9 bits (141), Expect = 6e-09
Identities = 45/123 (36%), Positives = 60/123 (48%), Gaps = 11/123 (8%)
Query: 129 RKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDAS 188
R K + R ++ G S K +S+ SK DE + S+ +
Sbjct: 229 RSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSK-------DEYEKSRSRSRSRSP 281
Query: 189 EEEDSNKKKSNRRSRSKSRSSHSR----SSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSS 244
+E KS RSRS+SRS+ S +RS SP R+ SRSRSRS S S+SRSRSS
Sbjct: 282 KENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSS 341
Query: 245 SRE 247
SR+
Sbjct: 342 SRD 344
Score = 42.7 bits (99), Expect = 4e-04
Identities = 47/191 (24%), Positives = 72/191 (37%), Gaps = 27/191 (14%)
Query: 167 YKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRS- 225
Y E ED DAD + Y L+ E + R + R +S S SSR
Sbjct: 37 YGFVEFEDSRDADDAVYELNGKELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRT 96
Query: 226 ----------RSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRK-RSY 274
R+ R + S S ++ R G + + + R + + RSY
Sbjct: 97 SGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSY 156
Query: 275 SSSSSSPER---------------NRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSS 319
S + ++ ++ R+ R S SG R + R+R RS R RSS S
Sbjct: 157 SDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRS 216
Query: 320 HSGSRSSSKKK 330
S S+S S+ +
Sbjct: 217 RSISKSRSRSR 227
>gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]
Length = 334
Score = 89.0 bits (219), Expect = 5e-18
Identities = 63/170 (37%), Positives = 81/170 (47%), Gaps = 25/170 (14%)
Query: 180 LSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSR------- 232
+ + + D EE S +KK +RR S S SS SR+ SR SRS+SRS SR
Sbjct: 1 MGRRSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSH 60
Query: 233 ----------SSSSSQSRSRSSSRERSRSRG-----SKSRSSSRSHRGSSSPRKRSYSSS 277
SSSSS R SR RSR RG +SRS SR+ R S PR RS+S S
Sbjct: 61 SYDRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRS 120
Query: 278 SSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
S R RSRSR +R+K R + + + + + H+ R S
Sbjct: 121 SERSSHRRTRSRSRDR---ERRKGRDKEKREKEKDKGKDKELHNIKRGES 167
Score = 73.6 bits (179), Expect = 2e-13
Identities = 53/133 (39%), Positives = 63/133 (47%), Gaps = 9/133 (6%)
Query: 207 RSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGS 266
RSS + SRS R RS S S S S + SR + + RS+SR RSH
Sbjct: 4 RSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSYD 63
Query: 267 SSPRKRSYSSSSSSPERNRKRSRSRSSSSGDR--------KKRRTRSRSPERRH-RSSSG 317
R RS SSSS R R RSRSR R + RR+RSR R H RSS
Sbjct: 64 RRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSSER 123
Query: 318 SSHSGSRSSSKKK 330
SSH +RS S+ +
Sbjct: 124 SSHRRTRSRSRDR 136
Score = 72.8 bits (177), Expect = 4e-13
Identities = 60/186 (32%), Positives = 86/186 (46%), Gaps = 30/186 (16%)
Query: 151 KESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS-- 208
+ S+ EEE + K++ +S+ ++KK R+SRSKSRS
Sbjct: 4 RSSDTEEESRSKRKKKHRRRSSSSS-----------SSDSRTYSRKKGGRKSRSKSRSWS 52
Query: 209 ------SHS------RSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKS 256
SHS SS SSS S R RSRSRSR S R SR +SR+R S+S
Sbjct: 53 RDLQPRSHSYDRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQR--SRSKSRTRRSRS 110
Query: 257 RSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSS 316
R RSH SS +RS + S R+R+R + R +++K + + + R S
Sbjct: 111 RPRLRSHSRSS---ERSSHRRTRSRSRDRERRKGRDKEKREKEKDKGKDKELHNIKRGES 167
Query: 317 GSSHSG 322
G+ +G
Sbjct: 168 GNIKAG 173
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 88.6 bits (218), Expect = 7e-18
Identities = 64/204 (31%), Positives = 105/204 (51%), Gaps = 18/204 (8%)
Query: 116 EREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDE 175
+R+ + +E GR++ + K G +KE E E E S+ +++E + +
Sbjct: 351 DRDREREKENERGRRRDRDYDKERG------NEREKERERSRERSKEQRSRGEVEEKKHK 404
Query: 176 DDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS 235
+D D ++ D + DS K+K + RSRS+ R SRS SR+ + RSRSRS+ +SS
Sbjct: 405 EDKDDRRHRDD---KRDSKKEKKHSRSRSRERKHRSRSRSRN---AGKRSRSRSKEKSSK 458
Query: 236 -SSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSS 294
++S+ +S+ R RS S+G ++ S +S + SP K S S ER+ KR S S
Sbjct: 459 HKNESKEKSNKRSRSGSQG-RTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKD 517
Query: 295 SGDRKKRR----TRSRSPERRHRS 314
D+ RR S E++H++
Sbjct: 518 QSDKHDRRRSQSIEQESQEKQHKN 541
Score = 84.7 bits (208), Expect = 1e-16
Identities = 62/250 (24%), Positives = 105/250 (42%), Gaps = 20/250 (8%)
Query: 94 AKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKES 153
++ R G+G +RE ER+ + E E R+K++ R +++ + +E
Sbjct: 278 SRSHHREGHGSSSFDRELEREKERQRLEREAKE--REKERRRSRSIDRGLERRRSRSRER 335
Query: 154 E-GEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSR 212
D + D + ++++ + + D +E + ++K RSR +S+ SR
Sbjct: 336 HRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSR 395
Query: 213 SSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKR 272
+ R R S + + S SR R R S+SRS + R S +++
Sbjct: 396 GEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEK 455
Query: 273 SYSSSSSSPERNRKRSRSRSSSSGD-------------RKKRRTRSRSPERRHRSSSGSS 319
S + S E++ KRSRS S D ++K R RSRS ER H+
Sbjct: 456 SSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHK----RD 511
Query: 320 HSGSRSSSKK 329
HS S+ S K
Sbjct: 512 HSDSKDQSDK 521
Score = 72.0 bits (175), Expect = 7e-13
Identities = 55/200 (27%), Positives = 98/200 (49%), Gaps = 18/200 (9%)
Query: 108 ERENVEYIER-EESDGEYD-EFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLS 165
+RE + ER D +YD E G +++K R ++ + + + E + +ED+D+
Sbjct: 353 DREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDD--- 409
Query: 166 KYKLDEDEDEDDADLSKYNLDASEEED----SNKKKSNRRSRSKSRSSHSRSSSRSSSPS 221
+ D+ D K++ S E S + + +RSRS+S+ S+ + S S
Sbjct: 410 --RRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKS 467
Query: 222 SSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSP 281
+ RSRS S+ R+ S +S+ R S + +SR +SRS RSH+ S S S
Sbjct: 468 NKRSRSGSQGRTDSVEKSKKREHSPSKEKSR-KRSRSKERSHKRDHS------DSKDQSD 520
Query: 282 ERNRKRSRSRSSSSGDRKKR 301
+ +R+RS+S S +++ +
Sbjct: 521 KHDRRRSQSIEQESQEKQHK 540
Score = 71.6 bits (174), Expect = 9e-13
Identities = 55/222 (24%), Positives = 95/222 (42%), Gaps = 14/222 (6%)
Query: 114 YIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDE 173
++ER S ++ R ++ S +E S E + +++ + + + E
Sbjct: 254 HVERRRSRSPRRSLSPRRSPRRSRS---RSHHREGHGSSSFDRELEREKERQRLEREAKE 310
Query: 174 DEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS----HSRSSSRSSSPSSSRSRSRS 229
E + S+ ++D E ++ + RSRS+SR R R R R R
Sbjct: 311 REKERRRSR-SIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRD 369
Query: 230 RSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSR 289
+ + + + R SRERS+ + S+ + H+ R+ S E+ RSR
Sbjct: 370 YDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSR 429
Query: 290 SRSSSSGDRKKR-RTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
SR +RK R R+RSR+ +R RS S S ++ SK+K
Sbjct: 430 SR-----ERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEK 466
Score = 67.4 bits (163), Expect = 2e-11
Identities = 64/216 (29%), Positives = 87/216 (40%), Gaps = 54/216 (25%)
Query: 168 KLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS-SHSRSSSRSSS------- 219
K+ +D E ++ ++ ++ + S RRS +SRS SH R SSS
Sbjct: 239 KIKKDGKEGAEEIDRH-VERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELER 297
Query: 220 ---------PSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRG-SKSRSSSRSHRGSSSP 269
+ R + R RSRS R RS SRER RSR S+ R R R
Sbjct: 298 EKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRERE 357
Query: 270 --------RKRSYSSS-SSSPERNRKRSRSRSSSSGDR---------------------- 298
R R Y + E+ R+RSR RS R
Sbjct: 358 KENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKR 417
Query: 299 ----KKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
+K+ +RSRS ER+HRS S S ++G RS S+ K
Sbjct: 418 DSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSK 453
Score = 51.6 bits (122), Expect = 1e-06
Identities = 41/128 (32%), Positives = 53/128 (41%), Gaps = 4/128 (3%)
Query: 197 KSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKS 256
+ N + K+R + + + R R RSRS S S RS R RSRS +
Sbjct: 226 QKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREG 285
Query: 257 RSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSS 316
SS R ++R + ER ++R RSRS DR R RSRS ER S
Sbjct: 286 HGSSSFDRELEREKERQ-RLEREAKEREKERRRSRSI---DRGLERRRSRSRERHRSRSR 341
Query: 317 GSSHSGSR 324
G R
Sbjct: 342 SRDRKGDR 349
Score = 35.0 bits (79), Expect = 0.092
Identities = 38/183 (20%), Positives = 68/183 (37%), Gaps = 37/183 (20%)
Query: 107 NERENVEYIEREESDGEYDEFGRKKKKYRGK---AVGPASILKEVEDKESEGEEEDEDED 163
NER + ++ G E R++ + R K + G K EDK+ +D+ +
Sbjct: 360 NERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDS 419
Query: 164 LSKYKLDEDEDED-------------DADLSKYNLDASEEEDSNKKKSNRRSRSKSRS-- 208
+ K + S+ +S+ ++ +K+KSN+RSRS S+
Sbjct: 420 KKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRT 479
Query: 209 -------------------SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERS 249
SRS RS S S+ +S SQS + S ++
Sbjct: 480 DSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQH 539
Query: 250 RSR 252
+++
Sbjct: 540 KNK 542
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 87.8 bits (216), Expect = 1e-17
Identities = 71/166 (42%), Positives = 90/166 (54%), Gaps = 29/166 (17%)
Query: 194 NKKKSNRRSRSKSRSSH-SRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSR 252
++ +S+ RSRS+SR S SRS S SS S S+SRSRSRS S S S+SRSRS SR RS+
Sbjct: 186 SRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKE 245
Query: 253 GSKSRSSSRSH-RGSSSPRKRSYSS----------------SSSSPERNRKRSRSRSSSS 295
S+S S +S R S+ + RS S S SP R++ +S+SRS S
Sbjct: 246 KSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQ 305
Query: 296 GDRKKRR-----TRSRSPER-----RHRS-SSGSSHSGSRSSSKKK 330
R + +R RS E+ R RS S G S S SRS SK K
Sbjct: 306 ERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSK 351
Score = 87.4 bits (215), Expect = 2e-17
Identities = 72/236 (30%), Positives = 113/236 (47%), Gaps = 20/236 (8%)
Query: 107 NERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSK 166
+++E +E+S G+ + K + +A V +S + + S+
Sbjct: 242 SKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSR 301
Query: 167 YKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSH-SRSSSRSSSPSSSRS 225
+ E E++ S +++KS R+SRS+SRS SRS SRS S S +
Sbjct: 302 SRSQERRVEEEKR-------GSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKR 354
Query: 226 RSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRS---SSRSHRGSSSPRKRSYSSSSS--- 279
+ R RSR S S+SRSRS S ERSR RGSK S SS+ + + R +S S S S
Sbjct: 355 KGRKRSREESRSRSRSRSKS-ERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSK 413
Query: 280 -----SPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
E +++ R S ++G ++ R+RSRS + + S S S+S+SK +
Sbjct: 414 EREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTR 469
Score = 85.5 bits (210), Expect = 6e-17
Identities = 66/210 (31%), Positives = 94/210 (44%), Gaps = 17/210 (8%)
Query: 129 RKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDAS 188
R + K R ++ + KE S+ + K + + ++ + N+
Sbjct: 227 RSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKP 286
Query: 189 EEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRER 248
+ ++ KS +SRS+S+ R S SR RS+ +S S S+SRS+ SR R
Sbjct: 287 KSRSPSRHKSKSKSRSRSQERRVEEEKRGSV---SRGRSQEKSLRQSRSRSRSKGGSRSR 343
Query: 249 SRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKR------R 302
SRSR SKS+ R R S RS S S S ER+RKR R S +G KK+ R
Sbjct: 344 SRSR-SKSK-DKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDR 401
Query: 303 TRSRSP------ERRHRSSSGSSHSGSRSS 326
++SRSP ER H S S G S
Sbjct: 402 SQSRSPSRSVSKEREHAKSESSQREGRGES 431
Score = 84.3 bits (207), Expect = 1e-16
Identities = 74/226 (32%), Positives = 102/226 (45%), Gaps = 62/226 (27%)
Query: 166 KYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKS---RSSHSRSSSRSSSPSS 222
K +L ED+ S Y+ S ++ + +R+SRS+S +SSHS+S SRS S S
Sbjct: 169 KIRLVEDKPGSRRRRS-YSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSR 227
Query: 223 SRSRSRSRSRSSS-SSQSRSRSSSRERSRSRG---------------------------- 253
SRS+SRSRS+S S S + +SRS S+E+SRSR
Sbjct: 228 SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPK 287
Query: 254 --------SKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSG--------- 296
SKS+S SRS KR S S E++ ++SRSRS S G
Sbjct: 288 SRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSR 347
Query: 297 ------------DRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
R++ R+RSRS + RS S S++ S KK
Sbjct: 348 SKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKK 393
Score = 75.5 bits (184), Expect = 6e-14
Identities = 62/164 (37%), Positives = 76/164 (46%), Gaps = 28/164 (17%)
Query: 185 LDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSR----SRSSSSSQSR 240
LD +E + + S+ R S+SRS S S RSRSRSR SRS S S
Sbjct: 160 LDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHS------RSRSRSRHSRKSRSRSGSSKS 213
Query: 241 SRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKK 300
S S SR RSRS GS+SRS SRS S R RS S SP + + RSRS S+ K
Sbjct: 214 SHSKSRSRSRS-GSRSRSKSRSR---SQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKS 269
Query: 301 R--------------RTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
+ + +SRSP R S S S R ++K
Sbjct: 270 KDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEK 313
Score = 61.6 bits (148), Expect = 9e-10
Identities = 50/152 (32%), Positives = 72/152 (47%), Gaps = 19/152 (12%)
Query: 117 REESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDED 176
R S + GRK+ + ++ + + E G + D SK K ED D
Sbjct: 345 RSRSKSKDKRKGRKRSREESRSRSRSR--SKSERSRKRGSKRDSKAGSSKKKKKEDTDRS 402
Query: 177 DA-----DLSKYNLDASEEE-------DSNKKKSNRRSRSKSRSSHSR-----SSSRSSS 219
+ +SK A E +S +N+ +RS+SRS+ S SRS S
Sbjct: 403 QSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRS 462
Query: 220 PSSSRSRSRSRSRSSSSSQSRSRSSSRERSRS 251
S+S++RSRS+SRS S+S+S SRS SR SRS
Sbjct: 463 KSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 86.3 bits (212), Expect = 3e-17
Identities = 61/141 (43%), Positives = 75/141 (53%), Gaps = 10/141 (7%)
Query: 189 EEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRER 248
E + K +S R R+++++S SRS S SSS SSS S S S SSSS S SRSSS
Sbjct: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
Query: 249 SRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSP 308
S + GS SR SS S SS R RS + R+RK R S DRK+R T
Sbjct: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHN---RDRKHRR-----SVDRKRRDTSGL-- 660
Query: 309 ERRHRSSSGSSHSGSRSSSKK 329
ER H+SS G S ++ S K
Sbjct: 661 ERSHKSSKGGSSRDTKGSKDK 681
Score = 79.7 bits (195), Expect = 3e-15
Identities = 63/147 (42%), Positives = 79/147 (53%), Gaps = 11/147 (7%)
Query: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRS----RSSSSSQSRSRSSSRER 248
S + N+ S+S+SRSS S SSS SS+ SSS S S S S SSSSS S S SSSR+
Sbjct: 562 SRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDS 621
Query: 249 SRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERN-----RKRSRSRSSSSGDRKKRRT 303
S S S S S SRS RG R R + S R+ R S+ SS D K +
Sbjct: 622 SSSTSSSSESRSRS-RGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKD 680
Query: 304 RSRSPERRHRSSSGSSHSGSRSSSKKK 330
++ +R+ RS S SS SG RSS ++
Sbjct: 681 KNSRSDRK-RSISESSRSGKRSSRSER 706
Score = 76.6 bits (187), Expect = 3e-14
Identities = 57/143 (39%), Positives = 71/143 (49%), Gaps = 10/143 (6%)
Query: 181 SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSR 240
S+ +S S+ S+ S S S SS SRSSS SSS +S S S S +SSSS+SR
Sbjct: 573 SRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESR 632
Query: 241 SRSSSRERSRSR------GSKSRSSS---RSHRGSSSPRKRSYSSSSSSPER-NRKRSRS 290
SRS R +R R K R +S RSH+ S R S R +RKRS S
Sbjct: 633 SRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSIS 692
Query: 291 RSSSSGDRKKRRTRSRSPERRHR 313
SS SG R R R R +R+ +
Sbjct: 693 ESSRSGKRSSRSERDRKSDRKDK 715
Score = 57.8 bits (138), Expect = 1e-08
Identities = 37/109 (33%), Positives = 51/109 (46%), Gaps = 1/109 (0%)
Query: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSR 252
S+ S SR S S+ S S SRS S +R R RS + + R S+
Sbjct: 609 SSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSK 668
Query: 253 GSKSRSSSRS-HRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKK 300
G SR + S + S S RKRS S SS S +R+ + R R S D+++
Sbjct: 669 GGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR 717
Score = 37.7 bits (86), Expect = 0.014
Identities = 29/123 (23%), Positives = 42/123 (34%), Gaps = 1/123 (0%)
Query: 136 GKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNK 195
G + S S D S E + +N D ++
Sbjct: 593 GSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDR 652
Query: 196 KKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRS-SSSSQSRSRSSSRERSRSRGS 254
K+ + +S S SSR + S ++ R RS S SS+S RSS ER R
Sbjct: 653 KRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDR 712
Query: 255 KSR 257
K +
Sbjct: 713 KDK 715
>gi|119226260 calcium homeostasis endoplasmic reticulum protein
[Homo sapiens]
Length = 916
Score = 86.3 bits (212), Expect = 3e-17
Identities = 59/118 (50%), Positives = 72/118 (61%), Gaps = 7/118 (5%)
Query: 203 RSKSRSSHSRSSS-RSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSR 261
R+K R+ + R+S PS SRSRS+SR RSSS S SRS SS SRSR SRS SR
Sbjct: 718 RAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSR---SRSCSR 774
Query: 262 SHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSS 319
S+ S R RS S S SS R+R +SRSRS S ++RR+RSRSP + GS+
Sbjct: 775 SY---SRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSN 829
Score = 80.9 bits (198), Expect = 1e-15
Identities = 57/107 (53%), Positives = 65/107 (60%), Gaps = 10/107 (9%)
Query: 190 EEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERS 249
+E N S RSRSKSR RSSSRS+S SS S S SRSRS S S+S SRS SR RS
Sbjct: 729 QEKRNSGPSRSRSRSKSRG---RSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRS 785
Query: 250 RSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSG 296
RSR S+SRS S+S R RS S S R+R RS + SS+G
Sbjct: 786 RSRSSRSRSRSQS-------RSRSKSYSPGRRRRSRSRSPTPPSSAG 825
Score = 73.6 bits (179), Expect = 2e-13
Identities = 51/103 (49%), Positives = 59/103 (57%), Gaps = 3/103 (2%)
Query: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSR 252
+ ++K + S S SRS SR SSSRS SRS S S S+SRSRS SR SRSR
Sbjct: 723 ARRRKGQEKRNSGPSRSRSRSKSRGR--SSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSR 780
Query: 253 GSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSS 295
S+SRS SRS R S + RS S S S R R RSRS + S
Sbjct: 781 -SRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPS 822
Score = 67.0 bits (162), Expect = 2e-11
Identities = 50/104 (48%), Positives = 57/104 (54%), Gaps = 5/104 (4%)
Query: 182 KYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSS---SRSSSPSSSRSRSRSRSRS-SSSS 237
K N S +K + SRS SRSS S S SRS S S S SRSRSRSRS S SS
Sbjct: 731 KRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSS 790
Query: 238 QSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSP 281
+SRSRS SR RS+S R SRS R + P S+S+ P
Sbjct: 791 RSRSRSQSRSRSKSYSPGRRRRSRS-RSPTPPSSAGLGSNSAPP 833
Score = 45.1 bits (105), Expect = 9e-05
Identities = 44/131 (33%), Positives = 59/131 (45%), Gaps = 31/131 (23%)
Query: 204 SKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSH 263
S R +S ++ R++ R+R R ++ S SR RS+SRG RSSSRS+
Sbjct: 698 SHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRG---RSSSRSN 754
Query: 264 RGSSSPRKRSYSSSSSSPERNRKRSR-SRSSSSGDRKKRRTRSRSPER---RHRSSSGSS 319
SR S+SS S R + R+ SRS R R RS S SS
Sbjct: 755 ------------------------SRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSS 790
Query: 320 HSGSRSSSKKK 330
S SRS S+ +
Sbjct: 791 RSRSRSQSRSR 801
Score = 44.3 bits (103), Expect = 2e-04
Identities = 45/116 (38%), Positives = 56/116 (48%), Gaps = 12/116 (10%)
Query: 218 SSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSS 277
S PS R R+ S + R+ R R R +G + R+S S R S + R SSS
Sbjct: 695 SPPSHDRPRN-SEGWEQNGLYEFFRAKMRARRR-KGQEKRNSGPS-RSRSRSKSRGRSSS 751
Query: 278 SSSPERNR-----KRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSK 328
S+ ++ RSRSRS S R R+RSRS R RSS S S SRS SK
Sbjct: 752 RSNSRSSKSSGSYSRSRSRSCS---RSYSRSRSRS-RSRSRSSRSRSRSQSRSRSK 803
Score = 28.5 bits (62), Expect = 8.6
Identities = 17/47 (36%), Positives = 23/47 (48%)
Query: 194 NKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSR 240
++ +S RSRSKS S R SRS SP+ S + + SR
Sbjct: 792 SRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSR 838
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 84.7 bits (208), Expect = 1e-16
Identities = 58/148 (39%), Positives = 85/148 (57%), Gaps = 12/148 (8%)
Query: 194 NKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSR--S 251
++ ++ R RS+SR+ R SRS +P+ RSR+RS R S S+S +R S R RSR +
Sbjct: 594 SRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPA 653
Query: 252 RGSKSRSSSRSHRG---SSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKR------R 302
R +SRS + + RG S +P +RS S S +P R R RSRSR+ G + R R
Sbjct: 654 RRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPAR-RGRSRSRTPRRGRSRSRSLVRRGR 712
Query: 303 TRSRSPERRHRSSSGSSHSGSRSSSKKK 330
+ SR+P+RR RS S S +S+++
Sbjct: 713 SHSRTPQRRGRSGSSSERKNKSRTSQRR 740
Score = 82.4 bits (202), Expect = 5e-16
Identities = 59/134 (44%), Positives = 77/134 (57%), Gaps = 14/134 (10%)
Query: 195 KKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGS 254
+ +S RR RS SRS +R SRS +P+ R RSRSR+ + +SRSR+ +R RSRSR
Sbjct: 553 RSRSARRGRSHSRSPATRGRSRSRTPAR---RGRSRSRTPARRRSRSRTPTRRRSRSRTP 609
Query: 255 KSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRS 314
R SRS +P +R S + SP R R RSRS + SG R+RSR+P RR RS
Sbjct: 610 ARRGRSRSR----TPARRR--SRTRSPVRRRSRSRSPARRSG-----RSRSRTPARRGRS 658
Query: 315 SSGSSHSGSRSSSK 328
S + RS S+
Sbjct: 659 RSRTPARRGRSRSR 672
Score = 81.6 bits (200), Expect = 9e-16
Identities = 65/154 (42%), Positives = 87/154 (56%), Gaps = 21/154 (13%)
Query: 193 SNKKKSNRRSRSKSRSSHSRSSSR----SSSPSSSRSRSRSRSRSSSSSQSRSRSSSRER 248
S K + +RSRS+SR +R++ R SS S+SR R RSRSRS + + R S R
Sbjct: 1764 SPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSR 1823
Query: 249 SRSRGSKSRSSSRSHRGSS----SPRKRSYSSSSSSPERNRKRSRSRSSSSGDRK----- 299
S +R SR+SSR RG S + RKRS S +S +P KRSRSR+S + R+
Sbjct: 1824 SPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAP---WKRSRSRASPATHRRSRSRT 1880
Query: 300 ----KRRTRSR-SPERRHRSSSGSSHSGSRSSSK 328
+RR+RSR SP R RS S +S + RS S+
Sbjct: 1881 PLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSR 1914
Score = 79.7 bits (195), Expect = 3e-15
Identities = 59/134 (44%), Positives = 71/134 (52%), Gaps = 10/134 (7%)
Query: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRER---S 249
S + +R RS+SR+ R SRS SP RSRS R S S Q R RS S +R S
Sbjct: 484 SRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWS 543
Query: 250 RSRGSKSRSSSRSHRG----SSSPRKRSYSSSSSSPERNRKRSRS---RSSSSGDRKKRR 302
RSR ++ R SRS R S SP R S S + R R RSR+ R S S +RR
Sbjct: 544 RSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRR 603
Query: 303 TRSRSPERRHRSSS 316
+RSR+P RR RS S
Sbjct: 604 SRSRTPARRGRSRS 617
Score = 79.3 bits (194), Expect = 4e-15
Identities = 62/147 (42%), Positives = 82/147 (55%), Gaps = 14/147 (9%)
Query: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQS---RSRSSSRERS 249
S+ + R RS+SR+ R SRS +P+ RSRSR+ +R S S++ R RS SR +
Sbjct: 562 SHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPA 621
Query: 250 RSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRT------ 303
R R S++RS R S SP +RS S S +P R R RSRSR+ + R + RT
Sbjct: 622 RRR-SRTRSPVRRRSRSRSPARRSGRSRSRTPAR-RGRSRSRTPARRGRSRSRTPARRSG 679
Query: 304 --RSRSPERRHRSSSGSSHSG-SRSSS 327
RSR+P RR RS S + G SRS S
Sbjct: 680 RSRSRTPARRGRSRSRTPRRGRSRSRS 706
Score = 76.3 bits (186), Expect = 4e-14
Identities = 62/175 (35%), Positives = 88/175 (50%), Gaps = 9/175 (5%)
Query: 164 LSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS-SHSRSSSRSSSPSS 222
+S++ E A + + S S + R R KS S + SR RS SP++
Sbjct: 430 VSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPAT 489
Query: 223 SRSRSRSRSRSSSS-SQSRSRSSSRERSRSRGSKSRSSSRSHRG-SSSPRKRSYSSSSSS 280
++ R RSRSR+ + SRSRS RSRS RS S RG S SP++ +S S ++
Sbjct: 490 AK-RGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNT 548
Query: 281 PERNRKRS--RSRSSSSGDRKKRRTRSRSPERRHRSSS---GSSHSGSRSSSKKK 330
R R RS R RS S + R+RSR+P RR RS S S SR+ ++++
Sbjct: 549 QRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRR 603
Score = 76.3 bits (186), Expect = 4e-14
Identities = 59/158 (37%), Positives = 84/158 (53%), Gaps = 12/158 (7%)
Query: 181 SKYNLDASEEEDSNKKKSNRRSRSKS---RSSHSRSSSRSSSPSSSRS---RSRSRSRSS 234
S+ A ++ + RRSR++S R S SRS +R S S SR+ R RSRSR+
Sbjct: 604 SRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTP 663
Query: 235 SS-SQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRS--R 291
+ +SRSR+ +R RSR SR+ +R R S +R S S S R R SR+ R
Sbjct: 664 ARRGRSRSRTPARRSGRSR---SRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQR 720
Query: 292 SSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKK 329
SG +R+ +SR+ +RR RS+S SR SS++
Sbjct: 721 RGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRR 758
Score = 75.5 bits (184), Expect = 6e-14
Identities = 56/140 (40%), Positives = 77/140 (55%), Gaps = 13/140 (9%)
Query: 201 RSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSS 260
R RS+SR+ +R SRS +P +R RSRSR+ + +SRSR+S R RSR S +
Sbjct: 1932 RRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTR 1991
Query: 261 RSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKR---------RTRSRSP--- 308
R R +SP R S S +SP R+RSRSR+ + R+ R R+RSRSP
Sbjct: 1992 RRSRSRTSPVTRRRSRSRTSPV-TRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAI 2050
Query: 309 ERRHRSSSGSSHSGSRSSSK 328
RR RS + + G RS ++
Sbjct: 2051 RRRSRSRTPRTARGKRSLTR 2070
Score = 73.9 bits (180), Expect = 2e-13
Identities = 85/276 (30%), Positives = 116/276 (42%), Gaps = 33/276 (11%)
Query: 82 RSECNMCNTPKYA----KLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGK 137
RSEC+ PK + R+ N + ER S+ D+ + +
Sbjct: 1477 RSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQR 1536
Query: 138 AVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKK 197
+ +S +E++ K S +E + D S D + +S E DS +
Sbjct: 1537 SRSGSS--QELDVKPSASPQERSESDSSP---DSKAKTRTPLRQRSRSGSSPEVDSKSRL 1591
Query: 198 SNRRSRS--------KSRSSHSRSSSRSSSPSSSRSRSRS---RSRSSSSSQSRSRS--- 243
S RRSRS K R++ S SSP R+ RSRS SSS+ R S
Sbjct: 1592 SPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEG 1651
Query: 244 -SSRERSRSRGSKSRSSSRSHRGSSSPRKRSYS-----SSSSSPERNRKRSRSRSSSSGD 297
SS E S KSR++ R R S P+ +S + SS SSPE RK SR S S
Sbjct: 1652 SSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSAS 1711
Query: 298 RKKRRTRSRSPERRHRSSSGSS---HSGSRSSSKKK 330
TRSR+P R RS S SS SRSS +++
Sbjct: 1712 SSPE-TRSRTPPRHRRSPSVSSPEPAEKSRSSRRRR 1746
Score = 73.6 bits (179), Expect = 2e-13
Identities = 63/154 (40%), Positives = 85/154 (55%), Gaps = 18/154 (11%)
Query: 194 NKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRE-RSRSR 252
++ + R RS+SR+ R SRS +P+ R RSRSR+ + S +SRSR+ +R RSRSR
Sbjct: 637 SRSPARRSGRSRSRTPARRGRSRSRTPAR-RGRSRSRTPARRSGRSRSRTPARRGRSRSR 695
Query: 253 -----GSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRS---RSRSSSSGDRKK---- 300
S+SRS R R S +R S SSS +N+ R+ RSRS+SS + KK
Sbjct: 696 TPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRIS 755
Query: 301 -RRTRSRSPER---RHRSSSGSSHSGSRSSSKKK 330
RR+RS S R + R S S SGS K+K
Sbjct: 756 SRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQK 789
Score = 73.6 bits (179), Expect = 2e-13
Identities = 55/136 (40%), Positives = 72/136 (52%), Gaps = 13/136 (9%)
Query: 198 SNRRSRSKSRSSHSRSSSR-----SSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSR 252
S SRS +R SR+SSR S +P +SR RSRSR+ + +SRSR+S RSR
Sbjct: 1818 SGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSR 1877
Query: 253 GSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSP---E 309
S R R +SP R S S +S R R RSR+ S +RR+RSR+P
Sbjct: 1878 SRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVS-----RRRSRSRTPPVTR 1932
Query: 310 RRHRSSSGSSHSGSRS 325
RR RS + ++ SRS
Sbjct: 1933 RRSRSRTPTTRRRSRS 1948
Score = 73.2 bits (178), Expect = 3e-13
Identities = 65/175 (37%), Positives = 87/175 (49%), Gaps = 31/175 (17%)
Query: 186 DASEEEDSNKKKSNRRSRS------KSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSS-Q 238
++S E + + R SRS KSR+ R SSRSS + ++R RSRS+SSS +
Sbjct: 1656 ESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPE 1715
Query: 239 SRSRSSSRER------SRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSP-------ERNR 285
+RSR+ R R S KSRSS R R +SSPR ++ S SP +R+R
Sbjct: 1716 TRSRTPPRHRRSPSVSSPEPAEKSRSSRR-RRSASSPRTKTTSRRGRSPSPKPRGLQRSR 1774
Query: 286 KRS----------RSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
RS R RS SS +RR RSRS R R G S SRS ++++
Sbjct: 1775 SRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQE 1829
Score = 72.4 bits (176), Expect = 5e-13
Identities = 61/164 (37%), Positives = 87/164 (53%), Gaps = 22/164 (13%)
Query: 181 SKYNLDASEEEDSNKKKSNRR---------SRSKSRSSHS-----RSSSRSSSPSSSRSR 226
S Y+ + ++S++ S RR SR +SRS S RS SR+S + RSR
Sbjct: 1818 SGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSR 1877
Query: 227 SRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRK 286
SR+ S S+SR+ SR RSRSR S +R SRS R S R+RS S +P R+
Sbjct: 1878 SRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRS-RASPVSRRRS---RSRTPPVTRR 1933
Query: 287 RSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
RSRSR+ ++ +RR+RSR+P R S + +R S+ +
Sbjct: 1934 RSRSRTPTT----RRRSRSRTPPVTRRRSRSRTPPVTRRRSRSR 1973
Score = 72.4 bits (176), Expect = 5e-13
Identities = 62/161 (38%), Positives = 83/161 (51%), Gaps = 29/161 (18%)
Query: 193 SNKKKSNRRSRSKSRSSH-SRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRS 251
S + R RS+SR+ +R SRS +P +R RSRSR+ + +SRSR+S R RS
Sbjct: 1935 SRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRS 1994
Query: 252 RGSKSRSSSRSHRGSSSP--RKRSYS---------SSSSSPERNRKRSRSRSSSSGDRKK 300
R S + R R +SP R+RS S S S +P RKRSRSRS + +
Sbjct: 1995 RSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLA---IR 2051
Query: 301 RRTRSRSPER--------------RHRSSSGSSHSGSRSSS 327
RR+RSR+P R RS+SGSS SRS++
Sbjct: 2052 RRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSAT 2092
Score = 71.2 bits (173), Expect = 1e-12
Identities = 67/188 (35%), Positives = 87/188 (46%), Gaps = 38/188 (20%)
Query: 181 SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRS----------- 229
S+ A ++ + R RS+SR+ R SRS +P RSRSRS
Sbjct: 658 SRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRT 717
Query: 230 ---RSRSSSSS---------QSRSRSSS-----RERSRSRGSKSRSSSRSHRGSSSPRKR 272
R RS SSS Q RSRS+S + R SR S+S SS RS S +R
Sbjct: 718 PQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRR 777
Query: 273 SYSSSSSSPERNRKR--SRSRSSSSGDRKKRRT---RSRS-----PERRHRSSSGSSHSG 322
S S SS P++ + RSRS SS + K RT RSRS P+++ ++ S SHS
Sbjct: 778 SLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSS 837
Query: 323 SRSSSKKK 330
S K K
Sbjct: 838 SSPHPKVK 845
Score = 70.1 bits (170), Expect = 3e-12
Identities = 50/131 (38%), Positives = 68/131 (51%), Gaps = 7/131 (5%)
Query: 201 RSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRS-SSRERSRSRGSKSRSS 259
RSRS R SRS R S ++ R RSRS+ +S SRS ++R RSRSR R
Sbjct: 524 RSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGR 583
Query: 260 SRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDR--KKRRTRSRSPERRHRSSSG 317
SRS +P +R S + + R+R R+ +R S R +RR+R+RSP RR S
Sbjct: 584 SRSR----TPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRS 639
Query: 318 SSHSGSRSSSK 328
+ RS S+
Sbjct: 640 PARRSGRSRSR 650
Score = 69.3 bits (168), Expect = 4e-12
Identities = 57/148 (38%), Positives = 72/148 (48%), Gaps = 17/148 (11%)
Query: 195 KKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGS 254
K++S+ S S S SS S SSS SSS SSS S S S S SSSSS S S + ++ + +
Sbjct: 2604 KRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPA 2663
Query: 255 KSRSSSRSHRGSSSPRK-----RSYSSSSSSPERNRKRS--------RSRSSSSGDRKKR 301
+ R S SPRK R S S SP R+ S +S SS G R+ +
Sbjct: 2664 SPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQ 2723
Query: 302 RTRSRSPERRHRSSSGS----SHSGSRS 325
R SRSP + R + S H SRS
Sbjct: 2724 RGDSRSPSHKRRRETPSPRPMRHRSSRS 2751
Score = 68.6 bits (166), Expect = 8e-12
Identities = 62/145 (42%), Positives = 80/145 (55%), Gaps = 20/145 (13%)
Query: 198 SNRRSRSKSRS-SHSRSSSRSSSPSSSRSRSR-------SRSRSSSSSQSRSRSSS---- 245
++RRSRS++ S RS SR+S S RSRSR SRSR+S S+ RSRS +
Sbjct: 1872 THRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVT 1931
Query: 246 RERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRS 305
R RSRSR +R SRS + R+ S S +P R+RSRSR+S +RR+RS
Sbjct: 1932 RRRSRSRTPTTRRRSRSRTPPVTRRR----SRSRTPPVTRRRSRSRTSPI---TRRRSRS 1984
Query: 306 R-SPERRHRSSSGSSHSGSRSSSKK 329
R SP R RS S +S R S +
Sbjct: 1985 RTSPVTRRRSRSRTSPVTRRRSRSR 2009
Score = 68.2 bits (165), Expect = 1e-11
Identities = 62/158 (39%), Positives = 78/158 (49%), Gaps = 28/158 (17%)
Query: 188 SEEEDSNKKKSNRRSRSKSRSS---------HSRSSSRSSSPSSSRSRSRSRSRSSSSSQ 238
S E + K + +RRSRS S S H RS S SS + +SRS R RS+SS +
Sbjct: 1693 SSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPR 1752
Query: 239 SRSRSSSRERSRSRGSK----SRSSSRSHRGSS-SPRKRSYSSSSSSPERNRKRSRSRSS 293
+++ S R RS K RS SRS R + + R+R S SS S R R+RSRSRS
Sbjct: 1753 TKTTS---RRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRS- 1808
Query: 294 SSGDRKKRRTR------SRSPERRHRSSSGSSHSGSRS 325
R RR R SRSP R+ S + S RS
Sbjct: 1809 ----RVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRS 1842
Score = 68.2 bits (165), Expect = 1e-11
Identities = 59/148 (39%), Positives = 64/148 (43%), Gaps = 29/148 (19%)
Query: 197 KSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSS----------- 245
K RRS S S SS S SSS SSS SSS S S S S SSSSS S S S S
Sbjct: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK 2661
Query: 246 ----------RERSRS--------RGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKR 287
RSRS R S+S S S R SP+ SSS ER +R
Sbjct: 2662 PASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRR 2721
Query: 288 SRSRSSSSGDRKKRRTRSRSPERRHRSS 315
+ S S K+RR RHRSS
Sbjct: 2722 GQRGDSRSPSHKRRRETPSPRPMRHRSS 2749
Score = 67.8 bits (164), Expect = 1e-11
Identities = 61/164 (37%), Positives = 80/164 (48%), Gaps = 29/164 (17%)
Query: 187 ASEEEDSNKKKSNRRSRSKSRSSHS----------RSSSRSSSPSSSRSRSRSRSRSSSS 236
+S E +R +R SRSS R SSRSS + ++R RSRS+SS
Sbjct: 1653 SSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASS 1712
Query: 237 S-QSRSRSSSRER------SRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPE---RNRK 286
S ++RSR+ R R S KSR SSR R +SSPR ++ S SP R +
Sbjct: 1713 SPETRSRTPPRHRRSPSVSSPEPAEKSR-SSRRRRSASSPRTKTTSRRGRSPSPKPRGLQ 1771
Query: 287 RSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
RSRSRS RR ++R+ RR RS S S S R S+ +
Sbjct: 1772 RSRSRS--------RREKTRTTRRRDRSGSSQSTSRRRQRSRSR 1807
Score = 67.8 bits (164), Expect = 1e-11
Identities = 70/175 (40%), Positives = 91/175 (52%), Gaps = 26/175 (14%)
Query: 175 EDDADLSKYNLDASEEEDSNKKKSNRRS------RSKSRSS---HSRSSSRSSSPSSSRS 225
E S+ S +++K+S R+ RS+SR+S H R SRS +P SR
Sbjct: 1829 ESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRR--SRSRTPLISRR 1886
Query: 226 RSRSRSRSSSSSQSRSRSS-SRERSRSRGSK-SRSSSRSHRGSSSPRKRSYS-------- 275
RSRSR+ S +SRSR+S +R RSRSR S SR SRS R R+RS S
Sbjct: 1887 RSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRS-RTPPVTRRRSRSRTPTTRRR 1945
Query: 276 SSSSSPERNRKRSRSRSSSSGDRKKRRTRSR-SPERRHRSSSGSSHSGSRSSSKK 329
S S +P R+RSRSR+ +RR+RSR SP R RS S +S R S +
Sbjct: 1946 SRSRTPPVTRRRSRSRTPPV---TRRRSRSRTSPITRRRSRSRTSPVTRRRSRSR 1997
Score = 67.8 bits (164), Expect = 1e-11
Identities = 59/141 (41%), Positives = 81/141 (57%), Gaps = 16/141 (11%)
Query: 201 RSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRS-SSRERSRSRG------ 253
R RS+SR+S +R SRS + SR RSRSR+ + +SRSR+ ++R RSRSR
Sbjct: 1897 RRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRR 1956
Query: 254 -SKSRS---SSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSR-SP 308
S+SR+ + R R +SP R S S +SP R+RSRSR+S +RR+RSR SP
Sbjct: 1957 RSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPV-TRRRSRSRTSPV---TRRRSRSRTSP 2012
Query: 309 ERRHRSSSGSSHSGSRSSSKK 329
R RS S + + R S +
Sbjct: 2013 VTRRRSRSRTPPAIRRRSRSR 2033
Score = 67.4 bits (163), Expect = 2e-11
Identities = 59/150 (39%), Positives = 77/150 (51%), Gaps = 16/150 (10%)
Query: 193 SNKKKSNRRSRSKSRSSH-SRSSSRSSSPSSSRSRSRSR-------SRSSSSSQSRSRSS 244
S + S R RS+SR+S SR SRS +P +R RSRSR SRS + +R RS
Sbjct: 1900 SRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSR 1959
Query: 245 SRE----RSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKK 300
SR R RSR S + R R +SP R S S +SP R+RSRSR+S +
Sbjct: 1960 SRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPV-TRRRSRSRTSPV---TR 2015
Query: 301 RRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
RR+RSR+P R S + R S+ +
Sbjct: 2016 RRSRSRTPPAIRRRSRSRTPLLPRKRSRSR 2045
Score = 65.1 bits (157), Expect = 8e-11
Identities = 81/258 (31%), Positives = 115/258 (44%), Gaps = 34/258 (13%)
Query: 99 RTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEE 158
R+G + + + ER ESD D + + R ++ +S EV+ K
Sbjct: 1538 RSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSS--PEVDSKSRLSPRR 1595
Query: 159 DEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKS-NRRSRSKSRS-----SHSR 212
+ K + A ++ D+S E + ++ RRSRS S S S
Sbjct: 1596 SRSGSSPEVK----DKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEG 1651
Query: 213 SSSRSSSPS-SSRSRSRSR-SRSSSSSQSRSRSSSRERSRSRGS-----KSRSSSRSHRG 265
SSS SSP +SR+ R SRSS +++SR+ R RS SR S K+R S RS
Sbjct: 1652 SSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRS-SRSSPELTRKARLSRRSRSA 1710
Query: 266 SSSP---------RKRSYSSSSSSPERNRKRSRSRSSSSGDRKK---RRTRSRSPERR-- 311
SSSP +RS S SS P + SR R S+S R K RR RS SP+ R
Sbjct: 1711 SSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGL 1770
Query: 312 HRSSSGSSHSGSRSSSKK 329
RS S S +R++ ++
Sbjct: 1771 QRSRSRSRREKTRTTRRR 1788
Score = 64.3 bits (155), Expect = 1e-10
Identities = 59/154 (38%), Positives = 75/154 (48%), Gaps = 16/154 (10%)
Query: 188 SEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRS--RSRSSSSSQSRSRSSS 245
S E + + RS S +S R SRS S + R R S SRS + +S SS
Sbjct: 1777 SRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSR 1836
Query: 246 RERSRSR-GSKSRSSSRSHRGSSSPRKRSYS---------SSSSSPERNRKRSRSRSSSS 295
R R RSR SR SRS R S +P KRS S S S +P +R+RSRSR+S
Sbjct: 1837 RRRGRSRTPPTSRKRSRS-RTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPV 1895
Query: 296 GDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKK 329
+RR+RSR+ R RS S +S R S +
Sbjct: 1896 ---SRRRSRSRTSVTRRRSRSRASPVSRRRSRSR 1926
Score = 63.5 bits (153), Expect = 2e-10
Identities = 55/169 (32%), Positives = 81/169 (47%), Gaps = 32/169 (18%)
Query: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRS---RSRSRSS--------SSSQSRS 241
S + RR RS SR+ R S SSS ++SR+ RSRS SS SS +SRS
Sbjct: 702 SRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRS 761
Query: 242 RSSSRERSRSRGSKSRSSS---------------RSHRGSSSPRKRSYS------SSSSS 280
SS R +++SR S RS S RS GSS P+ +S + SSSS
Sbjct: 762 LSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSP 821
Query: 281 PERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKK 329
P + + ++ SR S S + +S +P R+ +S ++ S + ++
Sbjct: 822 PPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRR 870
Score = 63.2 bits (152), Expect = 3e-10
Identities = 56/142 (39%), Positives = 75/142 (52%), Gaps = 14/142 (9%)
Query: 198 SNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRS------RSRSSSSSQSRSRSSSRERSRS 251
S RRSRS++ R S +S + RSRSR+ RSRS + +R RS SR +
Sbjct: 1884 SRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTR 1943
Query: 252 RGSKSRS---SSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSR-S 307
R S+SR+ + R R + P R S S +SP R+RSRSR+S +RR+RSR S
Sbjct: 1944 RRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSP-ITRRRSRSRTSPV---TRRRSRSRTS 1999
Query: 308 PERRHRSSSGSSHSGSRSSSKK 329
P R RS S +S R S +
Sbjct: 2000 PVTRRRSRSRTSPVTRRRSRSR 2021
Score = 60.8 bits (146), Expect = 2e-09
Identities = 40/124 (32%), Positives = 65/124 (52%), Gaps = 6/124 (4%)
Query: 212 RSSSRSSSPSSSRSRSRSRSRSSSSSQSRS-RSSSRERSRSRGSKSRSSS-RSHRGSSSP 269
R + + P+ + S R SSSS+S + + +++ + RG +S SSS R R SS
Sbjct: 155 RRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSK 214
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSP----ERRHRSSSGSSHSGSRS 325
+K+ S S S ++R + S D+K++R+RS +P R HRS+S S S S +
Sbjct: 215 KKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDT 274
Query: 326 SSKK 329
S +
Sbjct: 275 SRSR 278
Score = 60.1 bits (144), Expect = 3e-09
Identities = 56/156 (35%), Positives = 72/156 (46%), Gaps = 18/156 (11%)
Query: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSR---SRSSSRERS 249
S + RS KS +SSS SSP S + SR SSS + + S RE S
Sbjct: 395 SEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREIS 454
Query: 250 RSRGSKSRSSSRSHRGSSSP----RKRSYSSSSSSPERNRKRSR-------SRSSSSGDR 298
S SK+RS R+ R S R+ S S ++ +R R RSR SRS S R
Sbjct: 455 SSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWR 514
Query: 299 KKRRT----RSRSPERRHRSSSGSSHSGSRSSSKKK 330
+ R RSRSP+RR RS S SRS + ++
Sbjct: 515 RSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQR 550
Score = 59.7 bits (143), Expect = 3e-09
Identities = 65/263 (24%), Positives = 115/263 (43%), Gaps = 35/263 (13%)
Query: 91 PKYAKLEERTGYGGGFNERENVEYIERE----------ESDGEYDEFGRKKKKYRGKAVG 140
P Y EE +R N + ++ E E + +E G ++++ + K
Sbjct: 34 PDYKGEEELRRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVAT 93
Query: 141 PASILKEVE-----DKESEGEEEDEDEDLSKYKLDEDEDED---DADLSKYNLDASEEED 192
+L E + +E+ G+ E +L+E ++E +S +D S +
Sbjct: 94 FRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDP 153
Query: 193 SNKKKSNRRSRSKSRSSHS--RSSSRSSSPSSSRSRSRSRS----RSSSSSQSRSRSSSR 246
+ + ++ + +S R SS S SP+ + + + + RS SSS R R S
Sbjct: 154 QRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSS 213
Query: 247 ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSR 306
++ + R S+S S R HR + KR +++KR RSRS++ + +R RS
Sbjct: 214 KKKKHR-SESESKKRKHRSPTPKSKRK--------SKDKKRKRSRSTTPAPKSRRAHRST 264
Query: 307 SPERRHRSSSGSSHSGSRSSSKK 329
S + SSS +S S SRS++ K
Sbjct: 265 SADSA--SSSDTSRSRSRSAAAK 285
Score = 59.3 bits (142), Expect = 5e-09
Identities = 44/126 (34%), Positives = 54/126 (42%)
Query: 205 KSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHR 264
+ R + R SSS S S S S SSSSS S S SSS S S S S SSS
Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651
Query: 265 GSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSR 324
P+ +S P +RSRS + R+ S SP R R S S +
Sbjct: 2652 AKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQ 2711
Query: 325 SSSKKK 330
SSS ++
Sbjct: 2712 SSSSER 2717
Score = 57.8 bits (138), Expect = 1e-08
Identities = 52/130 (40%), Positives = 60/130 (46%), Gaps = 7/130 (5%)
Query: 200 RRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSS 259
RRS S S SS S SSS SSS SSS S S S S SS + +R S + +
Sbjct: 2530 RRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEA 2589
Query: 260 SRSHR-GSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGS 318
R R +P KR SSSSS + S S SSSS + S S SSS S
Sbjct: 2590 VREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS------SSSSS 2643
Query: 319 SHSGSRSSSK 328
S S S S +K
Sbjct: 2644 SSSSSPSPAK 2653
Score = 56.6 bits (135), Expect = 3e-08
Identities = 50/158 (31%), Positives = 76/158 (48%), Gaps = 22/158 (13%)
Query: 188 SEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSR-SRSSSSSQSRSRSSSR 246
S+ + + + ++KSR+ RS S SS P +S++ SR S SSSS + +S +
Sbjct: 790 SQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTP 849
Query: 247 ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSR 306
R S +S +++ S +P++RS SS PE + R+ SR S SG R +S
Sbjct: 850 PRQGSI-----TSPQANEQSVTPQRRSCFESSPDPEL-KSRTPSRHSCSGS-SPPRVKSS 902
Query: 307 SPERRHRSSSGS--------------SHSGSRSSSKKK 330
+P R+ S S S SHSGS S S +
Sbjct: 903 TPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSR 940
Score = 56.2 bits (134), Expect = 4e-08
Identities = 46/126 (36%), Positives = 64/126 (50%), Gaps = 13/126 (10%)
Query: 201 RSRSKSRSSH-SRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSS 259
R RS+SR+S +R SRS + +R RSRSR+ + +SRSR+ R RSR +
Sbjct: 1991 RRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAI 2050
Query: 260 SRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSS 319
R R + R S + SP R+RS S SSS R+RS +P + +
Sbjct: 2051 RRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSD------RSRSATP------PATRN 2098
Query: 320 HSGSRS 325
HSGSR+
Sbjct: 2099 HSGSRT 2104
Score = 55.5 bits (132), Expect = 7e-08
Identities = 54/252 (21%), Positives = 94/252 (37%), Gaps = 31/252 (12%)
Query: 97 EERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEG- 155
EE G E + + ++++ FG G + P +E + E
Sbjct: 109 EETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPP 168
Query: 156 ------EEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
E + + + + +D S+ + E + S+KKK +R +
Sbjct: 169 KPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRK 228
Query: 210 HSRSSSRSSSPSSSRSRSRSRS-----------RSSSSSQSRSRSSSRERSRSRGSKSRS 258
H + +S S + R RSRS RS+S+ + S +SR RSRS +K+ +
Sbjct: 229 HRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHT 288
Query: 259 SSRSHRGSSSPRKR-------------SYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRS 305
++ + R S R + + SSPE K+ S KK ++ +
Sbjct: 289 TALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSAT 348
Query: 306 RSPERRHRSSSG 317
R RSS+G
Sbjct: 349 RPSPSPERSSTG 360
Score = 55.5 bits (132), Expect = 7e-08
Identities = 41/141 (29%), Positives = 62/141 (43%), Gaps = 9/141 (6%)
Query: 191 EDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSR 250
+ KKK R R SS R +SS RS S S+ R S +S+ S+++ R
Sbjct: 186 KQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKR 245
Query: 251 SRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKR---RTRSRS 307
R + + +S R S S SSS +S RSRSRS+++ R+ S +
Sbjct: 246 KRSRSTTPAPKSRRAHRSTSADSASSSDTS------RSRSRSAAAKTHTTALAGRSPSPA 299
Query: 308 PERRHRSSSGSSHSGSRSSSK 328
RR + S G+ S+ +
Sbjct: 300 SGRRGEGDAPFSEPGTTSTQR 320
Score = 55.5 bits (132), Expect = 7e-08
Identities = 55/170 (32%), Positives = 78/170 (45%), Gaps = 30/170 (17%)
Query: 187 ASEEEDSNKKKSNRRSRS-------KSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSS-- 237
+S E + + S RRSRS KSR S RS S SS S ++SR R S SS
Sbjct: 726 SSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPC 785
Query: 238 ----------QSRSRSS---SRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSS------ 278
+SRS SS ++ R+ R S+S SS + S +P ++S+SSSS
Sbjct: 786 PKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVK 845
Query: 279 --SSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
+ P + S + S ++R SP+ +S + S HS S SS
Sbjct: 846 SGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSS 895
Score = 55.5 bits (132), Expect = 7e-08
Identities = 57/156 (36%), Positives = 79/156 (50%), Gaps = 22/156 (14%)
Query: 194 NKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSR-ERSRSR 252
++ S+ RS++KSR S RS S SS +S++ R S SSQ +++S + RSRS
Sbjct: 759 SRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSS 818
Query: 253 GS-----KSRSSSRSHRGSSSPRKRSYS------SSSSSPERNRK----RSRSRSSSSGD 297
S KS++ SR SSSP + S S +SP+ N + + RS SS D
Sbjct: 819 SSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPD 878
Query: 298 RK-KRRTRSR-----SPERRHRSSSGSSHSGSRSSS 327
+ K RT SR S R +SS+ S SRSSS
Sbjct: 879 PELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSS 914
Score = 55.1 bits (131), Expect = 9e-08
Identities = 47/148 (31%), Positives = 70/148 (47%), Gaps = 10/148 (6%)
Query: 191 EDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSR 250
+ S+ + S + S H+ SS S P+ + R S S +S + R++S
Sbjct: 414 QSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSH 473
Query: 251 S-----RGSKSRSSSRSHRGSS---SPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRR 302
S R +SRS + + RG S +P KR +S S S P+ R RS R S +RR
Sbjct: 474 SHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRS-PQWRRSRSAQRWGRSRS-PQRR 531
Query: 303 TRSRSPERRHRSSSGSSHSGSRSSSKKK 330
RSRSP+R S S ++ RS S ++
Sbjct: 532 GRSRSPQRPGWSRSRNTQRRGRSRSARR 559
Score = 53.1 bits (126), Expect = 3e-07
Identities = 51/146 (34%), Positives = 67/146 (45%), Gaps = 15/146 (10%)
Query: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRS--RSSSRERSR 250
S+ ++S++ SR SHS SS S + R S + ++ QS + R S E S
Sbjct: 818 SSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSP 877
Query: 251 SRGSKSRSSSR-SHRGSSSPRKRSYSSSSSSPERNRK-----------RSRSRSSSSGDR 298
KSR+ SR S GSS PR +S + SP R+ R RS S SS
Sbjct: 878 DPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPS 937
Query: 299 KKRRTRSRSPERRHRSSSGSSHSGSR 324
R T SR+ RR RS S S+ SR
Sbjct: 938 PSRVT-SRTTPRRSRSVSPCSNVESR 962
Score = 52.8 bits (125), Expect = 4e-07
Identities = 42/122 (34%), Positives = 58/122 (47%), Gaps = 7/122 (5%)
Query: 213 SSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSR--SSSRSHRGSSSPR 270
+S+ + PS+ + ++ R SSSS S S SSS S S S S SSS GSS P
Sbjct: 2511 ASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPV 2570
Query: 271 K-----RSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRS 325
+ + S + +P+ + R + RK+R + S S SSS SS S S S
Sbjct: 2571 QPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS 2630
Query: 326 SS 327
SS
Sbjct: 2631 SS 2632
Score = 52.0 bits (123), Expect = 7e-07
Identities = 81/292 (27%), Positives = 118/292 (40%), Gaps = 66/292 (22%)
Query: 97 EERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGE 156
E TG+ E N ++ + E+D D K+ ++ G +S E+ E
Sbjct: 1342 EMNTGFSSEVKEDLNGPFLNQLETDPSLD-----MKEQSTRSSGHSS--SELSPDAVEKA 1394
Query: 157 EEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSR--------- 207
++ +S LD + S + + E +D + +RRSRS S
Sbjct: 1395 GMSSNQSISSPVLDAVPRTPSRERSS-SASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGT 1453
Query: 208 -SSHSRSSSRSS------SPSSSRS---------------RSRSRSRSSSSSQSRSRSSS 245
S HS S S +PS RS R RSRS SS ++ +
Sbjct: 1454 PSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQ 1513
Query: 246 RERSRSR-------------GSKSRSSSRSH---RGSSSPRKRSYSSSSSSPERN----- 284
RERS S G +SRS S + S+SP++RS S SS +
Sbjct: 1514 RERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPL 1573
Query: 285 RKRSRSRSSSSGDRKK----RRTRS-RSPERRHR-SSSGSSHSGSRSSSKKK 330
R+RSRS SS D K RR+RS SPE + + ++ + SGS SS + K
Sbjct: 1574 RQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPK 1625
Score = 48.5 bits (114), Expect = 8e-06
Identities = 35/132 (26%), Positives = 55/132 (41%), Gaps = 12/132 (9%)
Query: 199 NRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRS 258
N + + R++ S S S R ++ + + S RE S SRS
Sbjct: 128 NEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRE-----SSSSRS 182
Query: 259 SSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGS 318
+ + + R S SSSP R RK+S + KK R+ S S +R+HRS +
Sbjct: 183 PTPKQKKKKKKKDRGRRSESSSPRRERKKSSKK-------KKHRSESESKKRKHRSPTPK 235
Query: 319 SHSGSRSSSKKK 330
S S+ +K+
Sbjct: 236 SKRKSKDKKRKR 247
Score = 48.5 bits (114), Expect = 8e-06
Identities = 49/133 (36%), Positives = 64/133 (48%), Gaps = 17/133 (12%)
Query: 201 RSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSS 260
++ +S + RS SS +SR+ SR S SS R +SS+ R S SRSSS
Sbjct: 859 QANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQ----SPSRSSS 914
Query: 261 RSHRGSS--SPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSP--ERRHRSSS 316
+ + SPR+RS+ S SSSP +R SR+ RR+RS SP R
Sbjct: 915 PQPKVKAIISPRQRSH-SGSSSPSPSRVTSRT--------TPRRSRSVSPCSNVESRLLP 965
Query: 317 GSSHSGSRSSSKK 329
SHSGS S K
Sbjct: 966 RYSHSGSSSPDTK 978
Score = 46.6 bits (109), Expect = 3e-05
Identities = 42/111 (37%), Positives = 57/111 (51%), Gaps = 14/111 (12%)
Query: 198 SNRRSRSKSRSSHSRSSSRSSSPSS---SRSRS------RSRSRSSSSSQSRSRSSS--- 245
+ RRSRS++ R S +SP + SRSR+ RSRSR+ + RSRS S
Sbjct: 1990 TRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLA 2049
Query: 246 -RERSRSRGSKSRSSSRS-HRGSSSPRKRSYSSSSSSPERNRKRSRSRSSS 294
R RSRSR ++ RS R + R+RS S SSS R+ +R+ S
Sbjct: 2050 IRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHS 2100
Score = 45.4 bits (106), Expect = 7e-05
Identities = 47/134 (35%), Positives = 65/134 (48%), Gaps = 12/134 (8%)
Query: 203 RSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS-SSQSRSRSSSRERSRSRGSKSRSSSR 261
+S++ S HS S S SS +S SRSSS + ++ S R+RS S GS S S SR
Sbjct: 882 KSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHS-GSSSPSPSR 940
Query: 262 SHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRK------KRRTRSRS----PERR 311
++ R RS S S+ R R SSS D K R++ S S P+ +
Sbjct: 941 VTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVK 1000
Query: 312 HRSSSGSSHSGSRS 325
++ G S SGS+S
Sbjct: 1001 AQTPPGPSLSGSKS 1014
Score = 39.7 bits (91), Expect = 0.004
Identities = 37/120 (30%), Positives = 53/120 (44%), Gaps = 9/120 (7%)
Query: 198 SNRRSRSKS-----RSSHSRSSSRSSSPSSSRS----RSRSRSRSSSSSQSRSRSSSRER 248
+ RRSRS++ R S SR+ S SRS R RSRSR+ +++ + +
Sbjct: 2014 TRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPP 2073
Query: 249 SRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSP 308
+ R S S SSS R ++ P R++S S + P S S R RSP
Sbjct: 2074 AIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSP 2133
Score = 39.7 bits (91), Expect = 0.004
Identities = 37/130 (28%), Positives = 57/130 (43%), Gaps = 3/130 (2%)
Query: 201 RSRSKSRSSHSRSSSRSSSPSSSR---SRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSR 257
+SR S + S SS +PS S ++ + RS S+ +SR + + GS+S
Sbjct: 2416 QSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSL 2475
Query: 258 SSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSG 317
SS +SS + S +P +S+G ++ + P + RSSS
Sbjct: 2476 SSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSS 2535
Query: 318 SSHSGSRSSS 327
SS S S SSS
Sbjct: 2536 SSSSSSSSSS 2545
Score = 38.1 bits (87), Expect = 0.011
Identities = 37/111 (33%), Positives = 52/111 (46%), Gaps = 7/111 (6%)
Query: 198 SNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSR 257
S+ + + +S++S S +SSP +S S S S S S S SR S SR
Sbjct: 1053 SSLQLKGQSQTSPDHRSD-TSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASR 1111
Query: 258 SSSRSHRG--SSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSR 306
S R RG S+SP + S SPE++R +S S S + D +SR
Sbjct: 1112 SPIRQDRGEFSASPMLK----SGMSPEQSRFQSDSSSYPTVDSNSLLGQSR 1158
Score = 36.2 bits (82), Expect = 0.041
Identities = 38/150 (25%), Positives = 61/150 (40%), Gaps = 12/150 (8%)
Query: 180 LSKYNLDASEEEDSNKKKSN--RRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSS 237
L +Y+ S D+ K R+S S S S + + +++ P S S S+S S
Sbjct: 964 LPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTP-PGPSLSGSKSPCPQEKSK 1022
Query: 238 QSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGD 297
S +S S G KS S+ P + + SS + + S S +
Sbjct: 1023 DSLVQSCPGSLSLCAGVKS---------STPPGESYFGVSSLQLKGQSQTSPDHRSDTSS 1073
Query: 298 RKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
+ R++ S SP + +S + SRSSS
Sbjct: 1074 PEVRQSHSESPSLQSKSQTSPKGGRSRSSS 1103
Score = 35.0 bits (79), Expect = 0.092
Identities = 41/149 (27%), Positives = 56/149 (37%), Gaps = 32/149 (21%)
Query: 211 SRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPR 270
S+S S + +++ S S + S E S G++ S+ + + + R
Sbjct: 2472 SQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERR 2531
Query: 271 KRSYSSSSSSPERNRKRSRSRSSSSGDR---------------------------KKRRT 303
S SSSSSS + S S SSSSG K+
Sbjct: 2532 SSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVR 2591
Query: 304 RSRSPE-----RRHRSSSGSSHSGSRSSS 327
R PE R+ RSSS SS S S SSS
Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSS 2620
Score = 34.3 bits (77), Expect = 0.16
Identities = 37/148 (25%), Positives = 57/148 (38%), Gaps = 10/148 (6%)
Query: 189 EEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRER 248
E++D +KK+ +S ++ S RSS+ P+ + + S + S
Sbjct: 336 EDKDKDKKE---KSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN 392
Query: 249 SRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRK------KRR 302
S S +R S P+ S SS SP+ K SR SSS K R
Sbjct: 393 PPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPT-KVSRHASSSPESPKPAPAPGSHR 451
Query: 303 TRSRSPERRHRSSSGSSHSGSRSSSKKK 330
S SP ++RS + S S + +
Sbjct: 452 EISSSPTSKNRSHGRAKRDKSHSHTPSR 479
Score = 32.0 bits (71), Expect = 0.78
Identities = 42/144 (29%), Positives = 62/144 (43%), Gaps = 22/144 (15%)
Query: 201 RSRSKSRSSHS-RSSSRSSSPSSSRSRS---------RSRSRSSSSSQSRSRSSSRERSR 250
R RS+SRS + R SRS +P ++R + R RS S SSS RSRS++ +R
Sbjct: 2039 RKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSS-DRSRSATPPATR 2097
Query: 251 SRG---------SKSRSSSRSHRG-SSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKK 300
+ + SR S S S +P R S P + + S +G
Sbjct: 2098 NHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMM 2157
Query: 301 RRTRSRSPERRHRSSSGSSHSGSR 324
R P+ + R+S +H+ SR
Sbjct: 2158 DGPGPRIPDHQ-RTSVPENHAQSR 2180
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 84.3 bits (207), Expect = 1e-16
Identities = 70/146 (47%), Positives = 81/146 (55%), Gaps = 19/146 (13%)
Query: 196 KKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRS-----RSSSSSQSRSRSSSRERSR 250
+ ++ R RS S SS S +S SSS SSSRS SRSR RS ++SRSRS SR RSR
Sbjct: 369 RNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSR 428
Query: 251 SRG-SKSRSSSRSHRGSSSPRKRSYSSSSSSPERN-----RKRSRSRSSSSGDRKKRRTR 304
SR S+SRS R H G S Y S SP R R+RSRSR S SGDR +R R
Sbjct: 429 SRRYSRSRSRGRRHSGGGSRDGHRY---SRSPARRGGYGPRRRSRSR-SHSGDRYRRGGR 484
Query: 305 SRSPERRHRSSSGSSHSGSRSSSKKK 330
RH SSS S S S S S+ +
Sbjct: 485 G----LRHHSSSRSRSSWSLSPSRSR 506
Score = 80.1 bits (196), Expect = 3e-15
Identities = 65/155 (41%), Positives = 76/155 (49%), Gaps = 21/155 (13%)
Query: 195 KKKSNRRSRSKSRSSHSRSSSRSSSPSSS-----RSRSRSRSRSSSSSQSRSRSSSRERS 249
+ S+ S S SR+S SRSSSRSSS S RS +RSRS S S+SRSRS RS
Sbjct: 376 RSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRS 435
Query: 250 RSRGSKSR----------SSSRSHRGSSSPRKRSYSSSSSSPERN------RKRSRSRSS 293
RSRG + S S + RG PR+RS S S S R S SRS
Sbjct: 436 RSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSR 495
Query: 294 SSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSK 328
SS R+RS + R H S S S SRS S+
Sbjct: 496 SSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQ 530
Score = 70.1 bits (170), Expect = 3e-12
Identities = 63/156 (40%), Positives = 78/156 (50%), Gaps = 28/156 (17%)
Query: 181 SKYNLDASEEEDSNKKKSNRRSRSKSRSS--------HSRSSSRSSSPSSSRSR--SRSR 230
S + +S ++ +S+ RS S+SR H+RS SRS S S SRSR SRSR
Sbjct: 377 SSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSR 436
Query: 231 SRSSSSSQSRSRSSSR-ERSRSR----GSKSRSSSRSHRGSSSPR----------KRSYS 275
SR S SR R RS +R G + RS SRSH G R RS S
Sbjct: 437 SRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRS 496
Query: 276 SSSSSPERNRKRSRSRS---SSSGDRKKRRTRSRSP 308
S S SP R+R +RSRS S S R + R+RS+SP
Sbjct: 497 SWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSP 532
Score = 67.8 bits (164), Expect = 1e-11
Identities = 72/200 (36%), Positives = 85/200 (42%), Gaps = 64/200 (32%)
Query: 194 NKKKSNRRSRSKSRSSHSR-SSSRSSSPSSSRSR-----------SRSRSRSSSSSQSRS 241
N R S S S SS SR SSSRSSS SSSRSR +RSRSRS S S+SRS
Sbjct: 370 NASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRS 429
Query: 242 RSSSRERSRSR-----------------------GSKSRSSSRSHRG------------- 265
R SR RSR R G + RS SRSH G
Sbjct: 430 RRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHH 489
Query: 266 SSSPRKRSYS-------------SSSSSPERNRKRSRSRSSS---SGDRKKRRTRSRSPE 309
SSS + S+S S S SP ++R RSRSRS S S R+K + SP
Sbjct: 490 SSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPA 549
Query: 310 RRHRSSSGSSHSGSRSSSKK 329
+ +G + + K
Sbjct: 550 VGEKLKKTEPAAGKETGAAK 569
Score = 64.7 bits (156), Expect = 1e-10
Identities = 73/249 (29%), Positives = 101/249 (40%), Gaps = 36/249 (14%)
Query: 92 KYAKL--EERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVE 149
K+AK EE+ Y G + R+ E+ ++K+ RG+ + P S +
Sbjct: 250 KHAKALEEEKAMYSGRRSRRQRREF---------------REKRLRGRKISPPSYARRDS 294
Query: 150 D-----KESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRS 204
K S E E S+ E++ S S+EE + + S
Sbjct: 295 PTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITS---FGGSDEEAAAAAAAAAASGV 351
Query: 205 KSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHR 264
+ + +P + S +R RS SSSSS S SR+SS S S+SR +R
Sbjct: 352 TTGKPPAPPQPGGPAPGRNAS-ARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYR 410
Query: 265 GSSSPRKRSYSSSSSSPERNRKRSRSRS----SSSGDRKKRRTRSRSPERR-----HRSS 315
R RS S S S R+R+ SRSRS S G + SRSP RR R S
Sbjct: 411 SGRHARSRSRSWSRSR-SRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRS 469
Query: 316 SGSSHSGSR 324
SHSG R
Sbjct: 470 RSRSHSGDR 478
Score = 55.5 bits (132), Expect = 7e-08
Identities = 48/149 (32%), Positives = 68/149 (45%), Gaps = 33/149 (22%)
Query: 200 RRSRSKSRSS------------HSRSSSRSS---SPSSSRSRSRSRSRSSSSSQSRSRSS 244
RRSRS+S S HS S SRSS SPS SRS +RSRS S S SQSRSRS
Sbjct: 467 RRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSR 526
Query: 245 SRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSP---ERNRKRSRSRSSSSGDRKKR 301
SR +S S SP + + ++SP E+ +K + +G K +
Sbjct: 527 SRSQS---------------PSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPK 571
Query: 302 RTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
T + R + + + ++++K
Sbjct: 572 LTPQEKLKLRMQKALNRQFKADKKAAQEK 600
Score = 48.9 bits (115), Expect = 6e-06
Identities = 51/178 (28%), Positives = 73/178 (41%), Gaps = 43/178 (24%)
Query: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSR 252
S + S S S+SRS +RS S S SPS SRSRSRSRS+S S S +R + + S +
Sbjct: 492 SRSRSSWSLSPSRSRSL-TRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAV 550
Query: 253 G---SKSRSSSRSHRGSSSPR---------------KRSYSSSSSSP---------ERNR 285
G K+ ++ G++ P+ R + + + ER
Sbjct: 551 GEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQE 610
Query: 286 KRSRSRSSSSGDRKKRRTR---------------SRSPERRHRSSSGSSHSGSRSSSK 328
+ R+ + R K R R SRSP R+ SS SRS S+
Sbjct: 611 REDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSR 668
Score = 39.3 bits (90), Expect = 0.005
Identities = 45/185 (24%), Positives = 65/185 (35%), Gaps = 59/185 (31%)
Query: 181 SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSR-------------- 226
S ++L S + +S+ S S+SRS SRS S+S SPS +R +
Sbjct: 496 SSWSLSPSRSRSLTRSRSHSPSPSQSRS-RSRSRSQSPSPSPAREKLTRPAASPAVGEKL 554
Query: 227 --------------------------------------SRSRSRSSSSSQSRSRSSSRER 248
+ ++ Q R +
Sbjct: 555 KKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDE 614
Query: 249 SRSRGSKSRSSSRSHRGSSSPR-KRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRS 307
R+ K R R R +R YS S SP + + SR SSS R++ R+RSRS
Sbjct: 615 LRAMARKIRMKERERREKEREEWERQYSRQSRSP--SPRYSREYSSS---RRRSRSRSRS 669
Query: 308 PERRH 312
P RH
Sbjct: 670 PHYRH 674
Score = 38.5 bits (88), Expect = 0.008
Identities = 31/84 (36%), Positives = 42/84 (50%), Gaps = 7/84 (8%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
DK++ E+ + E ++ E EDE A K + +E + +K+ R SR S
Sbjct: 593 DKKAAQEKMIQQE----HERQEREDELRAMARKIRM---KERERREKEREEWERQYSRQS 645
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRS 233
S S S SSSR RSRSRSRS
Sbjct: 646 RSPSPRYSREYSSSRRRSRSRSRS 669
Score = 33.5 bits (75), Expect = 0.27
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Query: 145 LKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRS 204
+++ +++ + +++ E + + + + E ED+ + E E +++ R
Sbjct: 582 MQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERE---RREKEREEWE 638
Query: 205 KSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS 235
+ S SRS S S S SR RSRSRS S
Sbjct: 639 RQYSRQSRSPSPRYSREYSSSRRRSRSRSRS 669
Score = 32.3 bits (72), Expect = 0.60
Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 5/116 (4%)
Query: 180 LSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQS 239
L K A +E + K K + + K R + + + +++ + + +
Sbjct: 554 LKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQERED 613
Query: 240 RSRSSSR-----ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRS 290
R+ +R ER R + + R S SP R SSS R+R RSRS
Sbjct: 614 ELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRS 669
Score = 31.6 bits (70), Expect = 1.0
Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 7/83 (8%)
Query: 137 KAVGPASILKEVEDKESEGEEEDEDEDLSKY-------KLDEDEDEDDADLSKYNLDASE 189
KA A+ K ++ + E EDE +++ + +++ +E + S+ + S
Sbjct: 591 KADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSP 650
Query: 190 EEDSNKKKSNRRSRSKSRSSHSR 212
S RRSRS+SRS H R
Sbjct: 651 RYSREYSSSRRRSRSRSRSPHYR 673
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 84.0 bits (206), Expect = 2e-16
Identities = 65/136 (47%), Positives = 78/136 (57%), Gaps = 13/136 (9%)
Query: 190 EEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERS 249
+E + NRR R++ SS ++ SR S SRS SRSRS+S + S+ R+RS S S
Sbjct: 1279 DEVRKTARLNRRPRNQESSSDEQTPSRDDD-SQSRSPSRSRSKSETKSRHRTRSVSYSHS 1337
Query: 250 RSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPE 309
RSR SRSS +SS R RSYS S S +R R+RSRSSS K RT SRS
Sbjct: 1338 RSR---SRSS------TSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRS-- 1386
Query: 310 RRHRSSSGSSHSGSRS 325
R RSSS HS SRS
Sbjct: 1387 -RSRSSSYDPHSRSRS 1401
Score = 81.3 bits (199), Expect = 1e-15
Identities = 70/172 (40%), Positives = 91/172 (52%), Gaps = 16/172 (9%)
Query: 164 LSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS---SHSRSSSRSSSP 220
L++ +++ D+ S+ + S ++ KS +SR ++RS SHSRS SRSS+
Sbjct: 1287 LNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSST- 1345
Query: 221 SSSRSRSRSRSRSS---SSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSS 277
SS RSRS SRSRS S ++RSRSSS +S + SRS SRS R RSY+
Sbjct: 1346 SSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYD 1405
Query: 278 SSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRS--SSGSSHSGSRSSS 327
S R+R RSRS+ S S R RS RR RS S GS RS S
Sbjct: 1406 SYY-SRSRSRSRSQRSDS------YHRGRSYNRRSRSCRSYGSDSESDRSYS 1450
Score = 75.5 bits (184), Expect = 6e-14
Identities = 67/159 (42%), Positives = 83/159 (52%), Gaps = 15/159 (9%)
Query: 181 SKYNLDASEEEDSNKKKSNRRSRSKS-RSSHSRSSSRSSSPSSSRSRSR-SRSRSSSSSQ 238
S Y+L +E S+ R S+S +S++S+ S RSS SS RSRSR SRSRS S S
Sbjct: 648 STYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSE-SSPRSRSRSSRSRSYSRSY 706
Query: 239 SRSRSSSRERSRSRGSKSRSSSRSHRG--SSSPRKRSYSSSSSSPERNRKRSRSRSSSSG 296
+RSRS + SRSR SRS SR+ S R SY+S SS R KR R RSS
Sbjct: 707 TRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKR-RLRSSGKK 765
Query: 297 DRKKRRTRSRSPER---------RHRSSSGSSHSGSRSS 326
+ + S S E+ R RSS +S SRSS
Sbjct: 766 NSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSS 804
Score = 75.5 bits (184), Expect = 6e-14
Identities = 74/203 (36%), Positives = 93/203 (45%), Gaps = 37/203 (18%)
Query: 139 VGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKS 198
V P S+ EV E S + +D+ + + SE + ++ +S
Sbjct: 1272 VRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRS 1331
Query: 199 NRRSRSKSRSSHSRSSSRSSSPSSSR-----SRSRSRSRSSS---------SSQSRSRSS 244
S S+SRS S SS RS S S SR SR R+RSRSSS SS+SRSRSS
Sbjct: 1332 VSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSS 1391
Query: 245 SRE-RSRSRG-------SKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSG 296
S + SRSR S+SRS SRS R S R RSY+ +RSRS S
Sbjct: 1392 SYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYN----------RRSRSCRSYGS 1441
Query: 297 DRKKRRTRSRSPERRHRSSSGSS 319
D + R+ S HRS S SS
Sbjct: 1442 DSESDRSYS-----HHRSPSESS 1459
Score = 65.9 bits (159), Expect = 5e-11
Identities = 75/274 (27%), Positives = 113/274 (41%), Gaps = 15/274 (5%)
Query: 35 GREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQ-CKTCSNVNWARRSECNMCNTPKY 93
G++ ++ A + AG + K +AEKS+ W+ + N+ + +
Sbjct: 1192 GKQDSSSASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLAAPNAATSSAVEVKVL 1251
Query: 94 AKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKES 153
+ E G R ++ + +DE + + R +S ++ ++
Sbjct: 1252 TTVPEMKPQG----LRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDD 1307
Query: 154 EGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRS 213
+ + SK + S + S + +S RSRS+ S R+
Sbjct: 1308 DSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRT 1367
Query: 214 SSRSS---SPSSSRSRSRSRSRSSS-SSQSRSRS----SSRERSRSRGSKSRSSSRSHRG 265
SRSS S S R+ SRSRSRSSS SRSRS S RSRSR S+S+ S HRG
Sbjct: 1368 RSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSR-SRSQRSDSYHRG 1426
Query: 266 SS-SPRKRSYSSSSSSPERNRKRSRSRSSSSGDR 298
S + R RS S S E +R S RS S R
Sbjct: 1427 RSYNRRSRSCRSYGSDSESDRSYSHHRSPSESSR 1460
Score = 60.8 bits (146), Expect = 2e-09
Identities = 51/112 (45%), Positives = 59/112 (52%), Gaps = 12/112 (10%)
Query: 194 NKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRG 253
+ K S RR +S S SSRSSS SS S R S+S QS SSR+ RS
Sbjct: 467 SSKSSTRRMKS---SCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRS-- 521
Query: 254 SKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRS 305
KS S S S RGSS R S SSS S R RS+SRSSS +KR ++S
Sbjct: 522 -KSHSQSYS-RGSSRSRTASKSSSHS-----RSRSKSRSSSKSGHRKRASKS 566
Score = 60.1 bits (144), Expect = 3e-09
Identities = 46/172 (26%), Positives = 78/172 (45%), Gaps = 10/172 (5%)
Query: 100 TGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEED 159
T G +++ E + + G+ + R+ K+ + + + I ++E +S
Sbjct: 420 TARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRI---LIPSDIESSKSSTRR-- 474
Query: 160 EDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSS 219
K D + + LS ++ + S+K + + S S S+S S+S S
Sbjct: 475 -----MKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYS 529
Query: 220 PSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRK 271
SSRSR+ S+S S S S+S+SRSSS+ R R SKS + S + P K
Sbjct: 530 RGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVK 581
Score = 58.9 bits (141), Expect = 6e-09
Identities = 48/117 (41%), Positives = 61/117 (52%), Gaps = 20/117 (17%)
Query: 184 NLDASEEEDSNKKKS---NRRSRSKSRSSHS-------------RSSSRSSSPSSSRSRS 227
++++S+ K S R SRS S SSH +SS SS S RS+S
Sbjct: 464 DIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKS 523
Query: 228 RSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRS---HRGSSSPRKRSYSSSSSSP 281
S+S S SS+SR+ S S SRSR SKSRSSS+S R S SPRK + S + P
Sbjct: 524 HSQSYSRGSSRSRTASKSSSHSRSR-SKSRSSSKSGHRKRASKSPRKTASQLSENKP 579
Score = 57.4 bits (137), Expect = 2e-08
Identities = 45/143 (31%), Positives = 64/143 (44%), Gaps = 6/143 (4%)
Query: 189 EEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRER 248
+++ +K R ++K R S SS S+ R +S SS S S S S +R
Sbjct: 439 KKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKR 498
Query: 249 SRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSG---DRKKRRTRS 305
S+ K SS +H S R +S+S S S R RSR+ S SS R K R+ S
Sbjct: 499 DWSKSDKDVQSSLTHSSRDSYRSKSHSQSYS---RGSSRSRTASKSSSHSRSRSKSRSSS 555
Query: 306 RSPERRHRSSSGSSHSGSRSSSK 328
+S R+ S S + S +K
Sbjct: 556 KSGHRKRASKSPRKTASQLSENK 578
Score = 57.4 bits (137), Expect = 2e-08
Identities = 49/139 (35%), Positives = 66/139 (47%), Gaps = 22/139 (15%)
Query: 207 RSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRE---RSRSRGSKSRSSSRSH 263
+S++S ++ + + SSS + S S S+ S+ S E RSRSR S+SRS SRS+
Sbjct: 647 QSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSY 706
Query: 264 ---RGSSSPRKRSYSSSSSSPERNRKRSRSR----------SSSSGDRKKRRTRSRSPER 310
R +S RS S SS S RN+ S+ SS G R KRR RS
Sbjct: 707 TRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSG--- 763
Query: 311 RHRSSSGSSHSGSRSSSKK 329
+ SH SSS+K
Sbjct: 764 ---KKNSVSHKKHSSSSEK 779
Score = 57.0 bits (136), Expect = 2e-08
Identities = 44/117 (37%), Positives = 60/117 (51%), Gaps = 5/117 (4%)
Query: 192 DSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRS----RSRSSSSSQSRSRSSSRE 247
+S+K + R S R SRSSS SS SS R S+S +S + SS+ RS S
Sbjct: 466 ESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHS 525
Query: 248 RSRSRG-SKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRT 303
+S SRG S+SR++S+S S S K SS S +R K R +S + K +T
Sbjct: 526 QSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKT 582
Score = 51.2 bits (121), Expect = 1e-06
Identities = 46/139 (33%), Positives = 63/139 (45%), Gaps = 13/139 (9%)
Query: 196 KKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSK 255
K R KS++ S ++R R R++ SSS + SR S+
Sbjct: 1258 KPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTP-------SRDDDSQ 1310
Query: 256 SRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRS----PERR 311
SRS SRS S S K + + S S +R RSRS +SS R R+RSR R
Sbjct: 1311 SRSPSRSR--SKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTR 1368
Query: 312 HRSSSGSSHSGSRSSSKKK 330
RSSS S+ R+SS+ +
Sbjct: 1369 SRSSSYRSYKSHRTSSRSR 1387
Score = 50.4 bits (119), Expect = 2e-06
Identities = 44/135 (32%), Positives = 60/135 (44%), Gaps = 8/135 (5%)
Query: 195 KKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGS 254
K++ ++ + K + + R R S SS SS R +SS +R RS S
Sbjct: 429 KRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSC-DRERSSRS 487
Query: 255 KSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSS-SGDRKKRRTRSRSPERRHR 313
S SS S + S + SS + R+ RS+S S S S + RT S+S
Sbjct: 488 SSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKS------ 541
Query: 314 SSSGSSHSGSRSSSK 328
SS S S SRSSSK
Sbjct: 542 SSHSRSRSKSRSSSK 556
Score = 44.3 bits (103), Expect = 2e-04
Identities = 56/264 (21%), Positives = 97/264 (36%), Gaps = 23/264 (8%)
Query: 89 NTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEV 148
+T A ++E TG +++RE ++ D + R ++ S +
Sbjct: 648 STYSLANIKE-TGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSY 706
Query: 149 EDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNR-RSRSKSR 207
S S ++ D + S+ + S D ++ R RS K
Sbjct: 707 TRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKN 766
Query: 208 S-SHSRSSSRSSS----------PSSSRSRSRSRSRSSSSSQSRSRSSSRERSRS----- 251
S SH + SS S SS R S SRSS S S SS + ++S
Sbjct: 767 SVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKE 826
Query: 252 -RGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRR----TRSR 306
+G R+ ++ + + +S S +R K + S +G + KR+ ++
Sbjct: 827 KQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWD 886
Query: 307 SPERRHRSSSGSSHSGSRSSSKKK 330
S R + +S + S SS K+
Sbjct: 887 SESNSERDVTKNSKNDSHPSSDKE 910
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/115 (29%), Positives = 47/115 (40%), Gaps = 13/115 (11%)
Query: 203 RSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRS 262
+ + + +HS S SS+ SSS S SSS S+ S R + + R RS R
Sbjct: 187 KKRKKPTHSEGSDSSSNSSSS-------SESSSESELEHERSRRRKHKRRPKVKRSKKRR 239
Query: 263 HRGSSS--PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRS----PERR 311
SSS PR + + ER+ + SS R+K R PE R
Sbjct: 240 KEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENR 294
Score = 41.6 bits (96), Expect = 0.001
Identities = 40/230 (17%), Positives = 90/230 (39%), Gaps = 14/230 (6%)
Query: 82 RSECNMCNTPKYAKLEERTGYGGGFNER--ENVEYIEREESDGEYDEFGRKKKKYRGKAV 139
RS C KY++ Y + + + + +E G+ + K++K RG+
Sbjct: 791 RSSC----VRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEK 846
Query: 140 GPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSN 199
+ +E + +E+ + L + ++ SK++ +++ E D K N
Sbjct: 847 SKSE--RECPHSKKRTLKENLSDHLRNGSKPKRKNYAG---SKWDSESNSERDVTKNSKN 901
Query: 200 RRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSS 259
S + +S S S + + ++SS+++ + + + S+ R S S S
Sbjct: 902 DSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSE 961
Query: 260 ---SRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSR 306
S S P+K + S + + K+ + + D+K + + +
Sbjct: 962 GSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRK 1011
Score = 40.4 bits (93), Expect = 0.002
Identities = 41/147 (27%), Positives = 58/147 (39%), Gaps = 3/147 (2%)
Query: 186 DASEEEDSNKKKSNRRSRSKSRSSHSRSSS--RSSSPSSSRSRSRSRSRSSSSSQSRSRS 243
D S E + K+ +R R+ S + S + S P SSR RS S+ S S
Sbjct: 356 DDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYY 415
Query: 244 SSRERSRSRGS-KSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRR 302
S +R G K R + + +K+ + ++ R S SS +R
Sbjct: 416 SDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRM 475
Query: 303 TRSRSPERRHRSSSGSSHSGSRSSSKK 329
S ER RSSS SSH S+ K
Sbjct: 476 KSSCDRERSSRSSSLSSHHSSKRDWSK 502
Score = 40.0 bits (92), Expect = 0.003
Identities = 44/236 (18%), Positives = 95/236 (40%), Gaps = 25/236 (10%)
Query: 92 KYAKLEERTGYGGGFNE-RENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVED 150
KY K +R+ ++E R +++Y E ++K+ +G+ + +
Sbjct: 784 KYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHN-----KQ 838
Query: 151 KESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSH 210
+++ GEE+ + E + E+ LS + + S+ + N S S S S
Sbjct: 839 EKNRGEEKSKSERECPHSKKRTLKEN---LSDHLRNGSKPKRKNYAGSKWDSESNSERDV 895
Query: 211 SRSSSRSSSPSSSRSRSRSRSRSSS------------SSQSRSRSSSRERSRSRGSKSRS 258
+++S S PSS + + S S S + S + S + + SK R+
Sbjct: 896 TKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRT 955
Query: 259 SSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRS 314
S+ GS S + ++ P++++ S+ +K + +++H++
Sbjct: 956 STSDSEGSCS----NSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKA 1007
Score = 37.4 bits (85), Expect = 0.019
Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 4/101 (3%)
Query: 214 SSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRG----SSSP 269
+++S + R + S S S S SSS S S RS R H+ S
Sbjct: 177 ATKSIKDVFEKKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSK 236
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPER 310
++R +SSS P + S D ++R+ S +R
Sbjct: 237 KRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKR 277
Score = 37.0 bits (84), Expect = 0.024
Identities = 52/237 (21%), Positives = 94/237 (39%), Gaps = 26/237 (10%)
Query: 117 REESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDED 176
R S G+ + KK + + +K D+ S + E Y D ++
Sbjct: 758 RLRSSGKKNSVSHKKHSSSSEKTLHSKYVKG-RDRSSCVRKYSESRSSLDYSSDSEQSSV 816
Query: 177 DADLSKYNLD--ASEEEDSNKKKSNR---RSRSKSRSSHSRSSSRSSSPSSS-RSRSRSR 230
A S + E NK++ NR +S+S+ HS+ + + S R+ S+ +
Sbjct: 817 QATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPK 876
Query: 231 SRSSSSSQSRSRSSSRERSRSRGSK--SRSSSRSHRGSSSPRKRS--------------Y 274
++ + S+ S S+S ER ++ SK S SS G ++ S
Sbjct: 877 RKNYAGSKWDSESNS-ERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKS 935
Query: 275 SSSSSSPERNR--KRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKK 329
S+++S P+ N K S+ R+S+S + + + GS + R +KK
Sbjct: 936 STNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKK 992
Score = 36.6 bits (83), Expect = 0.032
Identities = 24/84 (28%), Positives = 35/84 (41%), Gaps = 1/84 (1%)
Query: 247 ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSR 306
E+ R + + S S S SSS S S R RK R R +K+R+ S
Sbjct: 186 EKKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKR-RPKVKRSKKRRKEASS 244
Query: 307 SPERRHRSSSGSSHSGSRSSSKKK 330
S E R++ + RS + +K
Sbjct: 245 SEEPRNKHAMNPKGHSERSDTNEK 268
Score = 35.0 bits (79), Expect = 0.092
Identities = 26/92 (28%), Positives = 33/92 (35%), Gaps = 11/92 (11%)
Query: 192 DSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRS 251
+ +KK S S S+ S SS SS RSR R RS+ +E S S
Sbjct: 186 EKKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSS 245
Query: 252 -----------RGSKSRSSSRSHRGSSSPRKR 272
+G RS + R S KR
Sbjct: 246 EEPRNKHAMNPKGHSERSDTNEKRSVDSSAKR 277
Score = 33.1 bits (74), Expect = 0.35
Identities = 40/191 (20%), Positives = 72/191 (37%), Gaps = 15/191 (7%)
Query: 108 ERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKY 167
E+E +ER + E + K K R LKE + + ++ +
Sbjct: 824 EKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGS 883
Query: 168 KLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSH--------SRSSSRSSS 219
K D E + D++K N S+K++ S S+S S ++SS+ +S
Sbjct: 884 KWDS-ESNSERDVTK-NSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSL 941
Query: 220 PSSSRSRSRSRSRSSSSSQSRSRSSS-----RERSRSRGSKSRSSSRSHRGSSSPRKRSY 274
P + + S+ R+S+S S S+S + + GSK + K
Sbjct: 942 PDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKK 1001
Query: 275 SSSSSSPERNR 285
+P+R +
Sbjct: 1002 DKKHKAPKRKQ 1012
Score = 32.0 bits (71), Expect = 0.78
Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 8/90 (8%)
Query: 168 KLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRS-- 225
K E D + S + ++S E + ++S RR + K R RS R SSS
Sbjct: 191 KPTHSEGSDSSSNSSSSSESSSESELEHERSRRR-KHKRRPKVKRSKKRRKEASSSEEPR 249
Query: 226 -----RSRSRSRSSSSSQSRSRSSSRERSR 250
+ S S +++ RS SS +R +
Sbjct: 250 NKHAMNPKGHSERSDTNEKRSVDSSAKREK 279
Score = 31.6 bits (70), Expect = 1.0
Identities = 25/105 (23%), Positives = 40/105 (38%), Gaps = 12/105 (11%)
Query: 226 RSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNR 285
+ R + S S S S SSS S SSS S R+R + P+ R
Sbjct: 187 KKRKKPTHSEGSDSSSNSSS---------SSESSSESELEHERSRRRKH---KRRPKVKR 234
Query: 286 KRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
+ R + +SS + + + RS + S S+ ++K
Sbjct: 235 SKKRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREK 279
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 82.4 bits (202), Expect = 5e-16
Identities = 63/165 (38%), Positives = 84/165 (50%), Gaps = 22/165 (13%)
Query: 187 ASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSR 246
A E + +K+ + RSRS+SR + SSSR S SRSR RS S+S S +S+S R
Sbjct: 236 AIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRR-SRSRSRRRSHSKSRSRRRSKSPRRRR 294
Query: 247 ERSRSRGSKSRSSSRSH----------RGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSG 296
SR RG +SRS+S++ R + P+ S + S S R R+R RSRS +
Sbjct: 295 SHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRS 354
Query: 297 DRKKR---RTRSRSPE-RRH-------RSSSGSSHSGSRSSSKKK 330
+K R R SRSP RRH + S RS+SKKK
Sbjct: 355 PKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKK 399
Score = 69.3 bits (168), Expect = 4e-12
Identities = 57/154 (37%), Positives = 75/154 (48%), Gaps = 16/154 (10%)
Query: 186 DASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSS 245
D S +E K R ++S S+ + SRSRSRSR R + SS RS S
Sbjct: 213 DTSSKEIEEAMKRVREAQSLI-SAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRS 271
Query: 246 RERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRT-- 303
R R RS S SRS R S SPR+R S S R+R S++R D++K+R+
Sbjct: 272 RSRRRSH-----SKSRSRRRSKSPRRRR-SHSRERGRRSRSTSKTRDKKKEDKEKKRSKT 325
Query: 304 --RSRSPERRHRSSSGS-----SHSGSRSSSKKK 330
+S S RR RS+S S SG+RS K +
Sbjct: 326 PPKSYSTARRSRSASRERRRRRSRSGTRSPKKPR 359
Score = 68.9 bits (167), Expect = 6e-12
Identities = 64/213 (30%), Positives = 95/213 (44%), Gaps = 47/213 (22%)
Query: 146 KEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSK 205
KE+E+ E + L ++ D+ E+ S+ + S + +RRSRS+
Sbjct: 217 KEIEEAMKRVREA---QSLISAAIEPDKKEEKRRHSR-SRSRSRRRRTPSSSRHRRSRSR 272
Query: 206 SRS---SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQS----------------------- 239
SR S SRS RS SP RS SR R R S S+
Sbjct: 273 SRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYST 332
Query: 240 --RSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGD 297
RSRS+SRER R R SRS +RS + SP+++ S S SP R++K +
Sbjct: 333 ARRSRSASRERRRRR---SRSGTRSPKKPRSPKRK--LSRSPSPRRHKK----------E 377
Query: 298 RKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
+KK + + RS + R RS+S S + +++
Sbjct: 378 KKKDKDKERSRDERERSTSKKKKSKDKEKDRER 410
Score = 67.4 bits (163), Expect = 2e-11
Identities = 50/153 (32%), Positives = 69/153 (45%), Gaps = 11/153 (7%)
Query: 189 EEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRS------SSSSQSRSR 242
+ + S+K+ R + S ++ R SRSRSRS SSS RSR
Sbjct: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSR 270
Query: 243 SSSRERSRS-----RGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGD 297
S SR RS S R SKS RSH R RS S + + ++++ RS++
Sbjct: 271 SRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSY 330
Query: 298 RKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
RR+RS S ERR R S + S + S K+
Sbjct: 331 STARRSRSASRERRRRRSRSGTRSPKKPRSPKR 363
Score = 56.6 bits (135), Expect = 3e-08
Identities = 40/123 (32%), Positives = 58/123 (47%), Gaps = 6/123 (4%)
Query: 189 EEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRER 248
++ED KK+S +S S + SRS+SR R RSRS +RS +S R SR
Sbjct: 314 KKEDKEKKRSKTPPKSYSTARRSRSASRERR----RRRSRSGTRSPKKPRSPKRKLSRSP 369
Query: 249 SRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSP 308
S R K + + S R+RS S S +++++ R R S S K+ TR
Sbjct: 370 SPRRHKKEKKKDKDKERSRDERERSTSKKKKS--KDKEKDRERKSESDKDVKQVTRDYDE 427
Query: 309 ERR 311
E +
Sbjct: 428 EEQ 430
Score = 55.1 bits (131), Expect = 9e-08
Identities = 38/117 (32%), Positives = 55/117 (47%), Gaps = 3/117 (2%)
Query: 214 SSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRS 273
S +S + S + R R + S S + ++ + R S+SRS SR R SS R R
Sbjct: 209 SLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRR 268
Query: 274 YSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
S S ++ RSR RS S ++RR+ SR RR RS+S + KK+
Sbjct: 269 SRSRSRRRSHSKSRSRRRSKSP---RRRRSHSRERGRRSRSTSKTRDKKKEDKEKKR 322
Score = 50.1 bits (118), Expect = 3e-06
Identities = 41/131 (31%), Positives = 60/131 (45%), Gaps = 18/131 (13%)
Query: 193 SNKKKSNRRSRSKSRS----SHSRSSSRSSSPSSSRS---RSRSRSRSSSSSQSRSRSSS 245
S+ ++ RRSRS S++ + RS +P S S RSRS SR R R S
Sbjct: 295 SHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASR------ERRRRRS 348
Query: 246 RERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRS 305
R +RS K RS R S SPR+ + + R RS+S KK++++
Sbjct: 349 RSGTRS-PKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTS----KKKKSKD 403
Query: 306 RSPERRHRSSS 316
+ +R +S S
Sbjct: 404 KEKDRERKSES 414
Score = 35.4 bits (80), Expect = 0.071
Identities = 27/111 (24%), Positives = 48/111 (43%), Gaps = 11/111 (9%)
Query: 129 RKKKKYRGKAVGPASILKEVE-DKESEGEEEDEDEDLSKYKLDEDEDED-------DADL 180
R K+ ++ P KE + DK+ E ++ + SK K +D+++D D D+
Sbjct: 359 RSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDV 418
Query: 181 SKYNLDASEEE---DSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSR 228
+ D EEE DS K+K + ++ S ++ S S S+
Sbjct: 419 KQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESK 469
Score = 29.3 bits (64), Expect = 5.1
Identities = 16/92 (17%), Positives = 33/92 (35%)
Query: 195 KKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGS 254
K+K + + +SR RS+S+ +S S + +R E
Sbjct: 376 KEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSE 435
Query: 255 KSRSSSRSHRGSSSPRKRSYSSSSSSPERNRK 286
K + + + SP+ + S + + R+
Sbjct: 436 KEKKEEKKPIETGSPKTKECSVEKGTGDSLRE 467
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 82.0 bits (201), Expect = 7e-16
Identities = 87/248 (35%), Positives = 110/248 (44%), Gaps = 44/248 (17%)
Query: 118 EESDGEYDEFGRKK-------KKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLD 170
E S G+ DE G +K++G+ + P+S + K S
Sbjct: 763 EGSSGKKDEGGGGSSSQDHGGRKHKGE-LPPSSCQRRAGTKRSSRSSHRSQPSSG----- 816
Query: 171 EDEDEDDADL--------SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSS 222
DED DDA S+Y+ + EEEDS + S RSRS R S RSS RS S SS
Sbjct: 817 -DEDSDDASSHRLHQKSPSQYS-EEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSS 874
Query: 223 SRSR-----SRSRSRSSSSSQSRSRSSSRERSRSRGS------KSRSSSRSHRGSSSPRK 271
S SR RS S S S S R RS S S+ S+ H+ SSS
Sbjct: 875 DASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDD 934
Query: 272 RSYSSSSS-------SPERNRKRSRSRSSS-SGDRKKRRTRSRSPE--RRHRSSSGSSHS 321
S S S S + ER+R R RSRSSS S R KRR+RS + +R RS S
Sbjct: 935 YSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSR 994
Query: 322 GSRSSSKK 329
+RS S++
Sbjct: 995 STRSPSQR 1002
Score = 76.3 bits (186), Expect = 4e-14
Identities = 66/220 (30%), Positives = 93/220 (42%), Gaps = 15/220 (6%)
Query: 107 NERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSK 166
+++ +Y E EE + E R + + + S + S D D S
Sbjct: 829 HQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRS------SRRSYSSSSDASSDQSC 882
Query: 167 YK----LDEDEDEDDADLSKYNLDASEEED-----SNKKKSNRRSRSKSRSSHSRSSSRS 217
Y +D D +D S+ + S + D S+K +S R S S +S S S+S
Sbjct: 883 YSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQS 942
Query: 218 SSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSS 277
S S S +R RSRSR S S S SRS S+ RSRS + S SRS+ S RS S
Sbjct: 943 RSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQR 1002
Query: 278 SSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSG 317
S S +R+ SG R R++ + H SG
Sbjct: 1003 SGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSG 1042
Score = 74.3 bits (181), Expect = 1e-13
Identities = 73/214 (34%), Positives = 97/214 (45%), Gaps = 25/214 (11%)
Query: 118 EESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDE------DEDLSKYKLDE 171
+ S G+ D + K+ S +E ED SE S +
Sbjct: 812 QPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYS 871
Query: 172 DEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRS 231
+ +D S Y+ S +DS S+R SR S+ SH S S +SS+ RS+
Sbjct: 872 SSSDASSDQSCYSRQRSYSDDSYSDYSDR-SRRHSKRSH---DSDDSDYASSKHRSKRHK 927
Query: 232 RSS---------SSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPE 282
SS S S+SRSRS +RERSRSRG +SRSSS S R S R RS ++ S
Sbjct: 928 YSSSDDDYSLSCSQSRSRSRSHTRERSRSRG-RSRSSSCS-RSRSKRRSRSTTAHSWQRS 985
Query: 283 RNRKRSRSRSSSSGDR----KKRRTRSRSPERRH 312
R+ R RSRS+ S + +KR SPE RH
Sbjct: 986 RSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERH 1019
Score = 64.7 bits (156), Expect = 1e-10
Identities = 57/196 (29%), Positives = 81/196 (41%), Gaps = 18/196 (9%)
Query: 151 KESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSH 210
KE G+ + K + + + AD + + A E S K+K +R R K++SS
Sbjct: 666 KERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRK--KRKRKKNKSSA 723
Query: 211 SRSSSRSSSP----SSSRSRSRSRSRSSSSSQSRSR-----SSSRERSRSRGSKSRS-SS 260
S R P S S + R R R+ SQ RS SS ++ GS S+
Sbjct: 724 PADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGG 783
Query: 261 RSHRGSSSPR--KRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSP----ERRHRS 314
R H+G P +R + SS +R + S S D R +SP E
Sbjct: 784 RKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEE 843
Query: 315 SSGSSHSGSRSSSKKK 330
SGS HS SRS S ++
Sbjct: 844 DSGSEHSRSRSRSGRR 859
Score = 63.5 bits (153), Expect = 2e-10
Identities = 91/365 (24%), Positives = 131/365 (35%), Gaps = 63/365 (17%)
Query: 20 CGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNW 79
C + F + S N+ R K TE +IG + + +GL + K
Sbjct: 569 CNPLYFDFKLSRNKDARTKGTEKPK------DIGSSSKDHLQGLDPGEPNKSKEVGGEKI 622
Query: 80 ARRSECNMCNTPKYAKL------EERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKK 133
R S M + P +E G G E ++E G+ +KKKK
Sbjct: 623 VRSSGGRM-DAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRH-KKKKK 680
Query: 134 YRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSK----------- 182
++ + + E+K S+ E ++ + K K +++ AD +
Sbjct: 681 HKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGS 740
Query: 183 --------------YNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSR-- 226
EE S+ KK S S+ R PSS + R
Sbjct: 741 PAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAG 800
Query: 227 ----SRSRSRSSSSS---------------QSRSRSSSRERSRSRGSK-SRSSSRSHRGS 266
SRS RS SS +S S+ S E GS+ SRS SRS R
Sbjct: 801 TKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRH 860
Query: 267 SSPR--KRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSR 324
SS R +RSYSSSS + SR RS S RSR +R S S ++ S+
Sbjct: 861 SSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSK 920
Query: 325 SSSKK 329
SK+
Sbjct: 921 HRSKR 925
Score = 34.3 bits (77), Expect = 0.16
Identities = 32/156 (20%), Positives = 64/156 (41%), Gaps = 19/156 (12%)
Query: 183 YNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRS--------RSRSRSRSS 234
++ S +D+ K + + S S P+ S+ S R +
Sbjct: 574 FDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAP 633
Query: 235 SSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSS 294
+S + S + +E S GS++ + RS P K+ S S R++K+ + + SS
Sbjct: 634 ASGSACSGLNKQEPGGSHGSETEDTGRS-----LPSKKERSGKS---HRHKKKKKHKKSS 685
Query: 295 SGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
+ KR+ ++ + E+ ++ SG + +KK
Sbjct: 686 ---KHKRKHKADTEEKSSKAESGEKSKKRKKRKRKK 718
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 80.5 bits (197), Expect = 2e-15
Identities = 72/273 (26%), Positives = 108/273 (39%), Gaps = 9/273 (3%)
Query: 60 SRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREE 119
SRG S N + K N + ++ +E + ++ + G G N+ + + +
Sbjct: 487 SRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDND----KSDS 542
Query: 120 SDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDAD 179
G+ D + S + D S + + D D S + D ++
Sbjct: 543 GKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSS 602
Query: 180 LSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQS 239
S + D+S+ DS+ ++ SKS S S S S+S S S+ S S S SS SS S
Sbjct: 603 DSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNS 662
Query: 240 RSRSSSRERSRSRGS-----KSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSS 294
+ S S + S S S S SS S SS S SS SS + S S +S+
Sbjct: 663 SNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSN 722
Query: 295 SGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
S D + S SS SS S + S S
Sbjct: 723 SSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDS 755
Score = 77.0 bits (188), Expect = 2e-14
Identities = 55/178 (30%), Positives = 72/178 (40%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + D D S + + D ++ S + + + S+ SNR S S S
Sbjct: 808 DSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS 867
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S S +SS SS S S S SS SS S + S S S S S SS S S S
Sbjct: 868 SDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESS 927
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
S+SS S + S SS+S D S S + +SS SS S + S S
Sbjct: 928 NSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDS 985
Score = 76.6 bits (187), Expect = 3e-14
Identities = 58/175 (33%), Positives = 76/175 (43%), Gaps = 3/175 (1%)
Query: 156 EEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRR---SRSKSRSSHSR 212
+ D D S D + D +D S + + + DS+K +S+ S+S S S+S
Sbjct: 589 DSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSS 648
Query: 213 SSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKR 272
SS +S S S + S S S SS S S SSS + S S S SS S S S
Sbjct: 649 DSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSS 708
Query: 273 SYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
SS SS N S S SS+S D S S + S+S S S SS+
Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763
Score = 76.6 bits (187), Expect = 3e-14
Identities = 56/179 (31%), Positives = 79/179 (44%), Gaps = 3/179 (1%)
Query: 149 EDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS 208
E S+ + + + D + ++ D D+ S + D+S+ DS+ S+ S + S S
Sbjct: 630 ESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDS 689
Query: 209 SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSS 268
S S SS SS S S S S S SS S S S+S + S S S SS S S S
Sbjct: 690 SDSSDSSNSSESSDSSDSSDSDSSDSSDS---SNSNSSDSDSSNSSDSSDSSNSSDSSDS 746
Query: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
+ S SS S + + S SS S D S S + + S S S + S SS+
Sbjct: 747 SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805
Score = 76.6 bits (187), Expect = 3e-14
Identities = 56/181 (30%), Positives = 78/181 (43%), Gaps = 4/181 (2%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + + D + + + + D D+D S D+S+ +SN S+ + S S S
Sbjct: 682 DSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS----DSSDSSNSNSSDSDSSNSSDSSDS 737
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
+ S S SS SS+ S S S SS+SS S S S + S S S + S + SS
Sbjct: 738 SNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKK 329
S SS+SS + S S SS+S D S S S S S GS S S
Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSN 857
Query: 330 K 330
+
Sbjct: 858 R 858
Score = 75.9 bits (185), Expect = 5e-14
Identities = 55/178 (30%), Positives = 72/178 (40%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + D + D D+ S + D+S+ DS+ S+ S S S S
Sbjct: 667 DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDS 726
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S +SS SS S+S S S S+SS S S SS S S S SS S S S
Sbjct: 727 DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSN 786
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
+ S SS S + + S SS S D + + S SS SS+S S S
Sbjct: 787 DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS 844
Score = 75.9 bits (185), Expect = 5e-14
Identities = 56/182 (30%), Positives = 77/182 (42%), Gaps = 4/182 (2%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D D + + D D+ S + D+S+ DS+ ++ S S SS
Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792
Query: 210 HSRSSSRSS----SPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRG 265
S SS SS S SS S S S SS+SS S + S S + S S S S S
Sbjct: 793 DSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSD 852
Query: 266 SSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRS 325
S S + S+SS S + + + S SS S D + S S + + S S SS S + S
Sbjct: 853 SDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS 912
Query: 326 SS 327
S
Sbjct: 913 DS 914
Score = 75.9 bits (185), Expect = 5e-14
Identities = 58/176 (32%), Positives = 74/176 (42%), Gaps = 2/176 (1%)
Query: 153 SEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSR 212
S+ E D S D D D+ S + D+S DS++ ++ + + S SS+S
Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 942
Query: 213 SSSRS--SSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPR 270
SS S SS SS S S S SS SS S S SS + S S S SS S S S
Sbjct: 943 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN 1002
Query: 271 KRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + S SS S + S S + S S S S SS
Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058
Score = 75.5 bits (184), Expect = 6e-14
Identities = 62/184 (33%), Positives = 78/184 (42%), Gaps = 7/184 (3%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNL-DASEEEDSNKKKSNRRSRSKSRS 208
D + D D SK + D + + +D S N D+S+ DS+ ++ S S S
Sbjct: 612 DSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDS 671
Query: 209 SHSRSSSRSS----SPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHR 264
S S SS SS S SS S S S SS S S S S + S S S S S S+
Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNS 731
Query: 265 GSSSPRKRSYSSSSSSPERNRKRS--RSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSG 322
SS S SS SS N S S SS+S D S S + + S S S +
Sbjct: 732 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNS 791
Query: 323 SRSS 326
S SS
Sbjct: 792 SDSS 795
Score = 75.1 bits (183), Expect = 8e-14
Identities = 63/221 (28%), Positives = 85/221 (38%), Gaps = 5/221 (2%)
Query: 107 NERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILK-EVEDKESEGEEEDEDEDLS 165
N ++ + + +S D K + ++ S K + D S ++ D S
Sbjct: 600 NSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDS 659
Query: 166 KYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRS 225
+ + D +D S D+S DS+ + S S SS S SS SS SS S
Sbjct: 660 SNSSNSSDSSDSSDSS----DSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDS 715
Query: 226 RSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNR 285
S S SS S S S SS + S S S SS S S S + S SS S + +
Sbjct: 716 SDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSD 775
Query: 286 KRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S D S S S+S S S SS
Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS 816
Score = 75.1 bits (183), Expect = 8e-14
Identities = 62/186 (33%), Positives = 82/186 (44%), Gaps = 10/186 (5%)
Query: 149 EDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS 208
+ +S + D S D + D +D S D+S DSN ++ S S S
Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS----DSSNSSDSNDSSNSSDSSDSSNS 800
Query: 209 SHSRSSSRS-----SSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSH 263
S S +SS S SS S S + S S + S SS S S SS S GS S SS+RS
Sbjct: 801 SDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSD 860
Query: 264 RGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGS 323
+SS S SS+SS + S + SS+S D S S +SS SS S +
Sbjct: 861 SSNSSDSSDSSDSSNSSDSSDSSDS-NESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSN 919
Query: 324 RSSSKK 329
S S +
Sbjct: 920 SSDSSE 925
Score = 74.7 bits (182), Expect = 1e-13
Identities = 58/181 (32%), Positives = 76/181 (41%), Gaps = 1/181 (0%)
Query: 147 EVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKS 206
E D + + D S D D ++ S + ++S+ DS+ ++ S S
Sbjct: 700 ESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 759
Query: 207 RSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGS 266
SS+S SS SS S S S S + SS+ S S SS S S S SS S
Sbjct: 760 DSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSD 819
Query: 267 SSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
SS S +SS SS N S S SS S D + +RS SS SS S + S
Sbjct: 820 SSNSSDSSNSSDSSDSSNSSDS-SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSD 878
Query: 327 S 327
S
Sbjct: 879 S 879
Score = 74.7 bits (182), Expect = 1e-13
Identities = 58/184 (31%), Positives = 81/184 (44%), Gaps = 6/184 (3%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLS--KYNLDASEEEDSNKKKSNRRSRSKSR 207
D + D + S + D D +D S + D+S+ DSN+ ++ S S
Sbjct: 840 DSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSN 899
Query: 208 SSHSRSS----SRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSH 263
SS S SS S SS SS+ S S S SS +S S S+S + S S S + S S +
Sbjct: 900 SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNS 959
Query: 264 RGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGS 323
SS+ S S+SS S + + S SS S D S S + S S S + S
Sbjct: 960 SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019
Query: 324 RSSS 327
SS+
Sbjct: 1020 DSSN 1023
Score = 73.9 bits (180), Expect = 2e-13
Identities = 56/175 (32%), Positives = 73/175 (41%), Gaps = 1/175 (0%)
Query: 153 SEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSR 212
S+ + D S D D + S + D+S+ DS+ + S + SS+S
Sbjct: 833 SDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS 892
Query: 213 SSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKR 272
SS SS+ S S S S S SS S + S SS S + S SS+ S SS
Sbjct: 893 DSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSN 952
Query: 273 SYSSSSSSPERNRK-RSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS+SS N S S SS S D S S + S S S + S SS
Sbjct: 953 SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS 1007
Score = 73.6 bits (179), Expect = 2e-13
Identities = 52/177 (29%), Positives = 73/177 (41%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + D + + ++ + D+ S + D+S DS+ + S S + S
Sbjct: 766 DSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSD 825
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S SS S S +SS S S S S S S +RS S S S S S+S SS
Sbjct: 826 SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDS 885
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
+ S SS SS + S SS+S D S S E + S + +S S SS
Sbjct: 886 NESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 942
Score = 73.6 bits (179), Expect = 2e-13
Identities = 54/177 (30%), Positives = 67/177 (37%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + + D + + D D+ S + D+S+ DS+ + S S SS
Sbjct: 1026 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESS 1085
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S SS SS S S S S S SS S S SS S S S SS S S S
Sbjct: 1086 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS 1145
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + S SS S D S S + S S S S SS
Sbjct: 1146 DSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1202
Score = 73.6 bits (179), Expect = 2e-13
Identities = 54/177 (30%), Positives = 69/177 (38%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + D + + D D+ S + D+S+ DS++ + S + S SS
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS 1097
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S SS SS S S S S S+SS S S SS S S S SS S S S
Sbjct: 1098 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSS 1157
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + S SS S D S S + S S S S SS
Sbjct: 1158 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1214
Score = 73.6 bits (179), Expect = 2e-13
Identities = 55/177 (31%), Positives = 69/177 (38%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + D + E D D+ S + D+S+ DS+ + S S SS
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1121
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
+S SS SS S S S S S SS S S SS S S S SS S S+S
Sbjct: 1122 NSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1181
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + S SS S D S S + S S S+ S SS
Sbjct: 1182 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSS 1238
Score = 73.6 bits (179), Expect = 2e-13
Identities = 58/178 (32%), Positives = 70/178 (39%), Gaps = 1/178 (0%)
Query: 149 EDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS 208
+ +S E D S D + D +D S + D+S+ DS+ ++ S S S
Sbjct: 1074 DSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSS-DSSDSSDSSDSSNSSDSSDSSDS 1132
Query: 209 SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSS 268
S S SS SS S S S S S SS S S SS S S S SS S S S
Sbjct: 1133 SDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1192
Query: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + S SS S D S S E S S S S SS
Sbjct: 1193 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSS 1250
Score = 73.2 bits (178), Expect = 3e-13
Identities = 55/186 (29%), Positives = 76/186 (40%), Gaps = 9/186 (4%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEED---------SNKKKSNR 200
D D ++ + + + D+ S + D+S+ D SN S+
Sbjct: 775 DSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD 834
Query: 201 RSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSS 260
S S S S SS S S SS+RS S + S SS SS S + S S + S S S + S S
Sbjct: 835 SSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDS 894
Query: 261 RSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSH 320
SS S+SS S + + S SS+S D S S + S S +S
Sbjct: 895 SDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS 954
Query: 321 SGSRSS 326
S SS
Sbjct: 955 DSSNSS 960
Score = 73.2 bits (178), Expect = 3e-13
Identities = 55/177 (31%), Positives = 67/177 (37%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + D + D D+ S + D+SE DS+ ++ S S SS
Sbjct: 1044 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S SS SS S S S S S SS S S SS S S+S SS S S S
Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSS 1163
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + S SS S D S S + S S S S SS
Sbjct: 1164 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1220
Score = 72.8 bits (177), Expect = 4e-13
Identities = 53/178 (29%), Positives = 73/178 (41%), Gaps = 1/178 (0%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + + D + + + D +++ S + D+S DS+ S+ S S S+
Sbjct: 860 DSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSN 919
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSS-SRERSRSRGSKSRSSSRSHRGSSS 268
S SS S+S +S S S S SS S S SS S S S S S S S S S
Sbjct: 920 SSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDS 979
Query: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + S SS S D S S + + S S +S S SS
Sbjct: 980 SNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037
Score = 72.8 bits (177), Expect = 4e-13
Identities = 55/174 (31%), Positives = 72/174 (41%)
Query: 153 SEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSR 212
S + D S D + D+ S + D+S+ DS+ + S + S SS S
Sbjct: 951 SNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1010
Query: 213 SSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKR 272
SS SS+ S S + S S + S SS S S SS S S S +SS S S S
Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070
Query: 273 SYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + S SS+S D S S + S S S S SS
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1124
Score = 72.4 bits (176), Expect = 5e-13
Identities = 58/180 (32%), Positives = 74/180 (41%), Gaps = 5/180 (2%)
Query: 152 ESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNL-DASEEEDSNKKKSNRRSRSKSRSSH 210
+S + D S D + D +D N D+S DS+ + S S SS
Sbjct: 825 DSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD 884
Query: 211 SRSSSRSS----SPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGS 266
S SS SS S +SS S S S SS SS S + S S E S S + + S S + S
Sbjct: 885 SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944
Query: 267 SSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S S SS SS+ + S S S+S D S S + S S S S SS
Sbjct: 945 SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS 1004
Score = 72.4 bits (176), Expect = 5e-13
Identities = 55/174 (31%), Positives = 68/174 (39%)
Query: 153 SEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSR 212
S+ + + S D D+ S + D+S+ DS+ + S S SS S
Sbjct: 954 SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013
Query: 213 SSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKR 272
SS SS S+S S S S SS S S SS S S S SS S S S
Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1073
Query: 273 SYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S E + S SS S D S S + S S S + S SS
Sbjct: 1074 DSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1127
Score = 72.4 bits (176), Expect = 5e-13
Identities = 56/181 (30%), Positives = 75/181 (41%), Gaps = 1/181 (0%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D S + + S D + D +D S + D+S+ DS+ ++ S + S SS
Sbjct: 970 DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS-DSSDSSDSSDSSNSSDSSNSSDSS 1028
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
+S SS SS S S S S S SS+ S S SS S S S SS S S S
Sbjct: 1029 NSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS 1088
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKK 329
+ S SS S + + S SS S D S S + S S S + S SS
Sbjct: 1089 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSS 1148
Query: 330 K 330
+
Sbjct: 1149 E 1149
Score = 72.4 bits (176), Expect = 5e-13
Identities = 56/178 (31%), Positives = 71/178 (39%), Gaps = 1/178 (0%)
Query: 149 EDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS 208
+ +S + D S D E D +D S + D+S+ DS+ + S S S
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSS-DSSDSSDSSDSSDSSDSSDSSDS 1117
Query: 209 SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSS 268
S S +SS SS S S S S + S SS S S SS S S S SS S S S
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177
Query: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + S SS S D S S + S S S + SS
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESS 1235
Score = 72.4 bits (176), Expect = 5e-13
Identities = 54/177 (30%), Positives = 69/177 (38%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D E D + + + D D+ S + D+S+ DS+ + S S SS
Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S +SS SS S S S S S SS S S SS S S S SS S S S
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1196
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + S SS S D + S + S S S + S SS
Sbjct: 1197 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSS 1253
Score = 72.0 bits (175), Expect = 7e-13
Identities = 56/181 (30%), Positives = 75/181 (41%), Gaps = 5/181 (2%)
Query: 152 ESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYN-----LDASEEEDSNKKKSNRRSRSKS 206
+S + D S D + D +D S + D+S+ DS+ + S S
Sbjct: 649 DSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSS 708
Query: 207 RSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGS 266
S S SS S+S SS S S S SS+ S S SS + S S S SS S S
Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768
Query: 267 SSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S S SS+S + N + S SS S + S S + S S SS+S S+
Sbjct: 769 DSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN 828
Query: 327 S 327
S
Sbjct: 829 S 829
Score = 71.6 bits (174), Expect = 9e-13
Identities = 53/177 (29%), Positives = 68/177 (38%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + + D + D +D+ S + D+S DS+ + S S S
Sbjct: 760 DSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSD 819
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S SS S+S SS S + S S SS S S S S RS S S S S SS
Sbjct: 820 SSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDS 879
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S S+ SS+ + S S S S D S S S S +S S SS
Sbjct: 880 SDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSS 936
Score = 71.6 bits (174), Expect = 9e-13
Identities = 53/177 (29%), Positives = 69/177 (38%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + + D + + + D+ S + D+S DS+ + S S SS
Sbjct: 978 DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S SS SS S S S S S SS S S SS S S+S SS S S S
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS 1097
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + S SS+S D S S + + S S S S SS
Sbjct: 1098 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154
Score = 71.6 bits (174), Expect = 9e-13
Identities = 54/177 (30%), Positives = 68/177 (38%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + D + + D D+ S + D+S DS+ + S S SS
Sbjct: 984 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSS 1043
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S SS SS S+S S S S SS S S SS S S S +SS S S S
Sbjct: 1044 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + + S SS S D S S + S S S S SS
Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSS 1160
Score = 71.6 bits (174), Expect = 9e-13
Identities = 53/177 (29%), Positives = 70/177 (39%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + + D + + + D+ S + D+S+ DS+ + S S SS
Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S SS SS S S S S S SS S S +SS S S S SS S S S
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1118
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
+ S SS S + + S SS S D + S S + S S S S SS
Sbjct: 1119 DSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSS 1175
Score = 71.6 bits (174), Expect = 9e-13
Identities = 56/178 (31%), Positives = 70/178 (39%), Gaps = 4/178 (2%)
Query: 149 EDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS 208
+ +S + D S D + D +D S D+S+ DS+ + S S S
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS----DSSDSSDSSDSSESSDSSDSSNS 1093
Query: 209 SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSS 268
S S SS SS S S S S S SS+ S S SS S S S SS S S S
Sbjct: 1094 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDS 1153
Query: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + S SS+S D S S + S S S S SS
Sbjct: 1154 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1211
Score = 71.6 bits (174), Expect = 9e-13
Identities = 54/181 (29%), Positives = 70/181 (38%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + + D + + D D+ S + D+S DS+ + S S SS
Sbjct: 1053 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1112
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S SS SS+ S S S S S SS+ S S SS S S S SS S S S
Sbjct: 1113 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS 1172
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKK 329
S+SS S + + S SS S D S S + S S S S SS
Sbjct: 1173 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSN 1232
Query: 330 K 330
+
Sbjct: 1233 E 1233
Score = 70.9 bits (172), Expect = 2e-12
Identities = 59/181 (32%), Positives = 74/181 (40%), Gaps = 11/181 (6%)
Query: 153 SEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSR 212
S D D S D D +D S D+S DS+ + S S SS S
Sbjct: 719 SNSNSSDSDSSNSSDSSDSSNSSDSSDSS----DSSNSSDSSDSSDSSNSSDSSDSSDSS 774
Query: 213 SSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKR 272
SS SS+ S S S S S SS+ S S +SS S S S SS+ S +SS
Sbjct: 775 DSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD 834
Query: 273 SYSSSSSSPERNR-------KRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRS 325
S +SS SS + +RS SS+S D S S + S S S + S S
Sbjct: 835 SSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDS 894
Query: 326 S 326
S
Sbjct: 895 S 895
Score = 70.9 bits (172), Expect = 2e-12
Identities = 53/174 (30%), Positives = 71/174 (40%)
Query: 153 SEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSR 212
S+ + D + + + D+ S + D+S+ DS+ + S S SS+S
Sbjct: 960 SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019
Query: 213 SSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKR 272
SS SS S+S S S S SS S S SS + S S S SS S S S
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079
Query: 273 SYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + S SS S D S S + S+S S S SS
Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1133
Score = 70.9 bits (172), Expect = 2e-12
Identities = 56/178 (31%), Positives = 69/178 (38%), Gaps = 4/178 (2%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + D S D + D +D S D+S DS+ + S + S SS
Sbjct: 967 DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS----DSSNSSDSSDSSDSSDSSNSSDSS 1022
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
+S SS SS S S S S S SS S S +SS S S S SS S S S
Sbjct: 1023 NSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1082
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
S SS+S + + S SS S D S S S S S S SS+
Sbjct: 1083 ESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 1140
Score = 70.9 bits (172), Expect = 2e-12
Identities = 53/177 (29%), Positives = 67/177 (37%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + D + + D+ S + D+S+ DS+ + S S SS
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S SS SS S S S S S SS+ S S SS S S S SS S S+S
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1124
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + S SS S D S S + S S S S SS
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1181
Score = 70.9 bits (172), Expect = 2e-12
Identities = 53/178 (29%), Positives = 68/178 (38%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + D + D D+ S + D+SE DS+ + S S SS
Sbjct: 1110 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S SS SS+ S S S S S SS S S SS S S S SS S S S
Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
S SS S + + + S SS S D + S S +++GS S S
Sbjct: 1230 DSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDS 1287
Score = 70.5 bits (171), Expect = 2e-12
Identities = 54/179 (30%), Positives = 69/179 (38%), Gaps = 2/179 (1%)
Query: 149 EDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS 208
+ S D S D + D +D S + D+S DS+ + S S S
Sbjct: 819 DSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS--DSDSSNRSDSSNSSDSSDSSDSSNS 876
Query: 209 SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSS 268
S S SS S+ S+S S S + S S S S SS S + S SS+ S +SS
Sbjct: 877 SDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSS 936
Query: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
S SS SS N S + S SS + S SS S S S SS
Sbjct: 937 DSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS 995
Score = 70.5 bits (171), Expect = 2e-12
Identities = 54/174 (31%), Positives = 72/174 (41%)
Query: 153 SEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSR 212
S + D S + D ++ S + D+S+ DS+ ++ S S SS S
Sbjct: 957 SNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1016
Query: 213 SSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKR 272
+SS SS+ S S + S S S SS S S SS S S S SS S S S
Sbjct: 1017 NSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1076
Query: 273 SYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + + S SS S D S S + S S +S S SS
Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130
Score = 70.5 bits (171), Expect = 2e-12
Identities = 54/177 (30%), Positives = 67/177 (37%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D D + D D+ S + D+S+ DS+ + S S SS
Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S SS SS S S S S + S SS S S SS S S S SS S S S
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS+S + + S SS S D S S + S S +S S SS
Sbjct: 1131 DSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1187
Score = 70.5 bits (171), Expect = 2e-12
Identities = 56/178 (31%), Positives = 69/178 (38%), Gaps = 4/178 (2%)
Query: 149 EDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS 208
+ +S + D S D D +D S D+S+ DS+ + S S S
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS----DSSDSSDSSDSSDSSDSSESSDS 1087
Query: 209 SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSS 268
S S +SS SS S S S S S SS S S +SS S S S SS S S S
Sbjct: 1088 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDS 1147
Query: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + S SS S D S S + S S S S SS
Sbjct: 1148 SESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1205
Score = 70.1 bits (170), Expect = 3e-12
Identities = 53/177 (29%), Positives = 68/177 (38%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + D + + + D ++ S + D+S+ DS+ + S S SS
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1124
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S SS SS S S + S S S SS S S SS S S S SS S S S
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1184
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + S SS S D S S + S S S S SS
Sbjct: 1185 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSS 1241
Score = 69.7 bits (169), Expect = 3e-12
Identities = 52/178 (29%), Positives = 68/178 (38%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
+ + D + + D D+ S + D+S+ DS+ ++ S S SS
Sbjct: 1092 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESS 1151
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S SS SS S S S S S SS+ S S SS S S S SS S S S
Sbjct: 1152 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1211
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
S SS S + + + SS S D S S + S S S S S S
Sbjct: 1212 DSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDES 1269
Score = 69.3 bits (168), Expect = 4e-12
Identities = 61/210 (29%), Positives = 84/210 (40%), Gaps = 7/210 (3%)
Query: 120 SDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDAD 179
SDG YD + K +G + +D SE + + Y DE +D +
Sbjct: 447 SDG-YDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGS 505
Query: 180 LSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQS 239
SK +E++DS+ S S ++ + S +S S S SS+ S
Sbjct: 506 DSK----GAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSS 561
Query: 240 RSR-SSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSS-SPERNRKRSRSRSSSSGD 297
S SS + S S S SS S SS S SS+SS S + + S SS S D
Sbjct: 562 DSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 621
Query: 298 RKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
K ++S S S S SS S S SS
Sbjct: 622 SKSDSSKSESDSSDSDSKSDSSDSNSSDSS 651
Score = 69.3 bits (168), Expect = 4e-12
Identities = 55/178 (30%), Positives = 70/178 (39%), Gaps = 4/178 (2%)
Query: 149 EDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS 208
+ +S + + S D + D +D S D+S+ DS+ ++ S S S
Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSS----DSSDSSDSSDSSNSSDSSDSSDS 1066
Query: 209 SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSS 268
S S SS SS S S S S S+SS S S SS S S S SS S S S
Sbjct: 1067 SDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1126
Query: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + S SS S D S S + S S S + S SS
Sbjct: 1127 SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1184
Score = 69.3 bits (168), Expect = 4e-12
Identities = 57/187 (30%), Positives = 73/187 (39%), Gaps = 9/187 (4%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + + D + + D D+ S + D+S+ DS+ + S S SS
Sbjct: 1089 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSS 1148
Query: 210 HSRSSSRS--------SSPSSSRSRSRSRSRSSSSSQSRSRSSSRERS-RSRGSKSRSSS 260
S SS S SS SS S S S SS SS S S S + S S S S SS
Sbjct: 1149 ESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1208
Query: 261 RSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSH 320
S S S S SS S + N S SS S D S S + +S +
Sbjct: 1209 DSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDE 1268
Query: 321 SGSRSSS 327
S S+S S
Sbjct: 1269 SDSQSKS 1275
Score = 68.9 bits (167), Expect = 6e-12
Identities = 54/178 (30%), Positives = 75/178 (42%), Gaps = 7/178 (3%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + E D + D + D ++ + + D+S DS+ ++ S S SS
Sbjct: 694 DSSNSSESSDSSDSSDS---DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSS 750
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
+S SS SS S+S S S S SS S S S+ + S S S +SS S S S
Sbjct: 751 NSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS- 809
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
S SS SS + + S SS S D S S + S S SS+ S+S
Sbjct: 810 ---SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864
Score = 68.9 bits (167), Expect = 6e-12
Identities = 55/179 (30%), Positives = 79/179 (44%), Gaps = 6/179 (3%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
+ + D +E + + + D+D S D+S DS+ ++ S S SS
Sbjct: 875 NSSDSSDSSDSNESSNSSDSSDSSNSSDSDSS----DSSNSSDSSDSSNSSDSSESSNSS 930
Query: 210 HSRSSSRSS--SPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSS 267
+ +SS SS S SS S S + S SS+SS S + S S + + S S S +SS S S
Sbjct: 931 DNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSD 990
Query: 268 SPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S S SS+S + + S SS+S D S S + S S S S SS
Sbjct: 991 SSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSS 1049
Score = 68.9 bits (167), Expect = 6e-12
Identities = 53/177 (29%), Positives = 69/177 (38%), Gaps = 1/177 (0%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + + D + D ++ S + D+S+ DS+ + S S SS
Sbjct: 907 DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S S S SS S S + S S S SS S S SS S S S SS S S+S
Sbjct: 967 DS-SDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSS 1025
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
+ S SS S + + S SS S D S S + S S S S SS
Sbjct: 1026 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1082
Score = 68.9 bits (167), Expect = 6e-12
Identities = 55/178 (30%), Positives = 69/178 (38%), Gaps = 4/178 (2%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
+ E + ++ + D D+ S + D+S DS SN S S SS
Sbjct: 919 NSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDS----SNSSDSSDSNSS 974
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S SS SS S S S S S SS+ S S SS S S S +SS S S S
Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 1034
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
S SS S + + S SS S D S S + S S S S SS+
Sbjct: 1035 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN 1092
Score = 68.9 bits (167), Expect = 6e-12
Identities = 57/183 (31%), Positives = 67/183 (36%), Gaps = 5/183 (2%)
Query: 149 EDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYN-----LDASEEEDSNKKKSNRRSR 203
+ +S + D S D + D +D S + D+S DS+ + S
Sbjct: 984 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSS 1043
Query: 204 SKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSH 263
S SS S SS SS S S S S S SS S S SS S S S SS S
Sbjct: 1044 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103
Query: 264 RGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGS 323
S S S SS S + S SS S D S S E S S S S
Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSS 1163
Query: 324 RSS 326
SS
Sbjct: 1164 DSS 1166
Score = 68.9 bits (167), Expect = 6e-12
Identities = 55/178 (30%), Positives = 70/178 (39%), Gaps = 1/178 (0%)
Query: 149 EDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS 208
+ +S + D S D D +D S + D+S+ DS+ + S + S S
Sbjct: 1068 DSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSS-DSSDSSDSSDSSDSSDSSNSSDS 1126
Query: 209 SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSS 268
S S SS SS S+S S S S SS S S SS S S S SS S S S
Sbjct: 1127 SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1186
Query: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + S SS S D S S + + S S S SS
Sbjct: 1187 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSS 1244
Score = 68.6 bits (166), Expect = 8e-12
Identities = 53/177 (29%), Positives = 67/177 (37%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D D + D ++ S + D+S+ DS+ + S S SS
Sbjct: 996 DSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1055
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
+S SS SS S S S S S SS S S SS S S S SS S S S
Sbjct: 1056 NSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1115
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S+SS S + + S SS+S D S S + S S S S SS
Sbjct: 1116 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS 1172
Score = 68.2 bits (165), Expect = 1e-11
Identities = 55/177 (31%), Positives = 73/177 (41%), Gaps = 2/177 (1%)
Query: 153 SEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSR 212
S+ + D S + + D+ S + D+S DS+ + S+ S
Sbjct: 801 SDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSD 860
Query: 213 SSSRSS-SPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRK 271
SS+ S S SS S S S SS S++S + S S + S S S S SS S S S
Sbjct: 861 SSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNS 920
Query: 272 RSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRS-SSGSSHSGSRSSS 327
S SS+S + + S SS S D S S S SS SS S S SS
Sbjct: 921 SDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS 977
Score = 68.2 bits (165), Expect = 1e-11
Identities = 55/176 (31%), Positives = 70/176 (39%), Gaps = 1/176 (0%)
Query: 152 ESEGEEEDEDEDLSKYKLDEDEDEDDADL-SKYNLDASEEEDSNKKKSNRRSRSKSRSSH 210
+S + + S D D +D S + D+S DS+ + S S SS+
Sbjct: 943 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN 1002
Query: 211 SRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPR 270
S SS SS S S + S S + S SS+ S S SS S S S SS S S S
Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1062
Query: 271 KRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + S SS S D S S + S S S S SS
Sbjct: 1063 SSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1118
Score = 67.8 bits (164), Expect = 1e-11
Identities = 59/185 (31%), Positives = 80/185 (43%), Gaps = 9/185 (4%)
Query: 149 EDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDS-NKKKSNRRSRSKSR 207
+ +S + D S + + D +D S + D+S DS N S+ S S
Sbjct: 784 DSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS--DSDSSNSSDSSNSSDSSDSSNSSDS 841
Query: 208 SSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQS-----RSRSS-SRERSRSRGSKSRSSSR 261
S S SS S S SS+RS S + S SS SS S S SS S E S S S S+S
Sbjct: 842 SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS 901
Query: 262 SHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHS 321
S S S SS+S + + + S +S+S D S S + + S S +S
Sbjct: 902 DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961
Query: 322 GSRSS 326
S SS
Sbjct: 962 SSNSS 966
Score = 67.8 bits (164), Expect = 1e-11
Identities = 58/178 (32%), Positives = 70/178 (39%), Gaps = 2/178 (1%)
Query: 149 EDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS 208
E S D S D + + +D S + D+S DS+ S+ S S + S
Sbjct: 925 ESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS-DSSNSSDSSDSNSSDSSDSSNSS 983
Query: 209 SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSS 268
S SS S S SS S + S S SS S S SS S + S SS S SS
Sbjct: 984 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSS 1043
Query: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS SS + S S SS S D S S E S S +S S SS
Sbjct: 1044 DSSDSSDSSDSSNSSDSSDS-SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSS 1100
Score = 67.4 bits (163), Expect = 2e-11
Identities = 54/179 (30%), Positives = 70/179 (39%), Gaps = 4/179 (2%)
Query: 149 EDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS 208
+ +S + + S D D +D S D+S+ DS+ + S + S S
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS----DSSDSSDSSDSSDSSDSSNSSDS 1060
Query: 209 SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSS 268
S S SS SS S S S S S SS S S SS S S S SS S S S
Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1120
Query: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
S SS S + + + S SS S + S S + S S S S SS+
Sbjct: 1121 SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1179
Score = 67.0 bits (162), Expect = 2e-11
Identities = 54/178 (30%), Positives = 74/178 (41%), Gaps = 2/178 (1%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + + D + D D+ S + D+S+ DS+ + S S SS
Sbjct: 1119 DSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1178
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGS-SS 268
+S SS SS S S S S S SS S S SS S S S SS S+ S SS
Sbjct: 1179 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSS 1238
Query: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS+SS + S +S S D +++S + + S S S GS S+
Sbjct: 1239 DSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGN-GNNNGSDSDSDSEGSDSN 1295
Score = 66.2 bits (160), Expect = 4e-11
Identities = 54/177 (30%), Positives = 68/177 (38%), Gaps = 1/177 (0%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D D E + D ++ S + D+S DS+ + S S S+
Sbjct: 913 DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN 972
Query: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
S SS S+S SS S S S S SS S S SS S S S SS S S+S
Sbjct: 973 SSDSSDSSNSSDSSDS-SDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSS 1031
Query: 270 RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S SS S + + S SS+S D S S + S S S S SS
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS 1088
Score = 66.2 bits (160), Expect = 4e-11
Identities = 55/181 (30%), Positives = 76/181 (41%), Gaps = 3/181 (1%)
Query: 149 EDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS 208
+ +S + D S D D +D S+ + D+S+ DS+ + S S S
Sbjct: 1116 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESS-DSSDSSDSSDSSDSSDSSDSSDS 1174
Query: 209 SHSRSSSRS--SSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGS 266
S S +SS S SS SS S S S SS SS S S S + S S S S S S
Sbjct: 1175 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNES 1234
Query: 267 SSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S S SS SS+ + S S S+S + ++S+S + S S S S
Sbjct: 1235 SDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDS 1294
Query: 327 S 327
+
Sbjct: 1295 N 1295
Score = 62.8 bits (151), Expect = 4e-10
Identities = 60/213 (28%), Positives = 80/213 (37%), Gaps = 33/213 (15%)
Query: 147 EVEDKESEGEE---EDEDEDLSKYKLDEDEDEDDADLSKYNLDASEE------------- 190
+ +DK +G++ DE + D + + YN D S++
Sbjct: 454 DFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDD 513
Query: 191 -----EDSNKKKSN-----------RRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSS 234
D+N SN + K +S S S S SS SS S S S
Sbjct: 514 DSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSD 573
Query: 235 SSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRS-S 293
S+S S S SS + S S S S SS S S S S SS S + S+S S S
Sbjct: 574 SNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDS 633
Query: 294 SSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
S D K + S S + S S S + S SS
Sbjct: 634 SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666
Score = 62.4 bits (150), Expect = 5e-10
Identities = 54/176 (30%), Positives = 67/176 (38%), Gaps = 6/176 (3%)
Query: 150 DKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
D + D E D D+ S + D+S+ DS+ + S S SS
Sbjct: 1128 DSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1187
Query: 210 HSRSSSRS--SSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSS 267
S SS S SS SS S S S SS SS S S S + S S S S S SS
Sbjct: 1188 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSS 1247
Query: 268 SPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGS 323
+ S SS SS + S SG+ + S S S S+HS S
Sbjct: 1248 NSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDS----EGSDSNHSTS 1299
Score = 57.0 bits (136), Expect = 2e-08
Identities = 42/153 (27%), Positives = 65/153 (42%), Gaps = 2/153 (1%)
Query: 147 EVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKS 206
E D + D + + D ++ S + D+S+ DS+ + S S
Sbjct: 1149 ESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1208
Query: 207 RSSHSRSSSRS--SSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHR 264
SS S SS S SS SS S S S SS SS S S+S + S S S +S +
Sbjct: 1209 DSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDE 1268
Query: 265 GSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGD 297
S + + +++ S + + + S S S+S D
Sbjct: 1269 SDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 52.8 bits (125), Expect = 4e-07
Identities = 50/214 (23%), Positives = 83/214 (38%), Gaps = 14/214 (6%)
Query: 128 GRKKKKYRGKAVGPASILK--EVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNL 185
G++ K G +G ++ EV + E G++ + + D + D D ++
Sbjct: 398 GKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDD 457
Query: 186 DASEEEDSNKKKSNRRSRSKSRSSHSRSSSR--------SSSPSSSRSRSRSRSRSSSSS 237
+ + +D N + + + S + SSSR S + + S S+ S S
Sbjct: 458 KSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDS 517
Query: 238 QSRSRSSSRERSRSRGSKSRSSSRSHRG----SSSPRKRSYSSSSSSPERNRKRSRSRSS 293
S + +S + + G+ S S +G S S S +SS SS + S S SS
Sbjct: 518 TSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS 577
Query: 294 SSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
S D + S SS+ S S S SS
Sbjct: 578 SDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSS 611
Score = 50.4 bits (119), Expect = 2e-06
Identities = 70/299 (23%), Positives = 100/299 (33%), Gaps = 82/299 (27%)
Query: 107 NERENVEYIEREESDGEYDEFGRKKKK---YRGKAVGPASILKEVEDKESEGEEEDED-- 161
N RE+ R + E G+ + K +G + G +I KEV +G E ED
Sbjct: 348 NHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEV----GKGNEGKEDKG 403
Query: 162 --------------------------------------------EDLSKYKLD----EDE 173
+ Y D + +
Sbjct: 404 QHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGD 463
Query: 174 DEDDADLSKYNLDASEEEDSN------------KKKSNRR-------------SRSKSRS 208
D + +D S N DA+ E D+N + K N S S + +
Sbjct: 464 DPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNN 523
Query: 209 SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSS 268
S S + + + + +S S SS S S S+S + S S S S S+ S SS
Sbjct: 524 SDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSS 583
Query: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
S SS S S + + S SS S D S S +S S SS S S+S S
Sbjct: 584 DSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDS 642
Score = 36.6 bits (83), Expect = 0.032
Identities = 39/190 (20%), Positives = 65/190 (34%), Gaps = 18/190 (9%)
Query: 146 KEVEDKESEGEE---EDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRS 202
KE E GE+ ++ D S DEDEDE D +EE N K S+ S
Sbjct: 225 KEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGD-------DEDEEAGNGKDSSNNS 277
Query: 203 RSKSRSSHSRSSSRSSS---PSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSS 259
+ + H + SS S S+ + ++ +S+ S G +
Sbjct: 278 KGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNG 337
Query: 260 SRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSS 319
S+ + R S NR S + + G + + + P +R+ +
Sbjct: 338 SQRIEDTQKLNHR-----ESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEV 392
Query: 320 HSGSRSSSKK 329
G+ K
Sbjct: 393 GKGNEGKEDK 402
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 80.5 bits (197), Expect = 2e-15
Identities = 61/129 (47%), Positives = 73/129 (56%), Gaps = 12/129 (9%)
Query: 205 KSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHR 264
+SR RS+SR S S SRSRS S RS RSRS R+R R R S+SR RS
Sbjct: 4 ESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRER-SRSRDKRRSR- 61
Query: 265 GSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSS---GSSHS 321
S RKR S S +R+R+R RSRS R +RR+RSRS RR RSSS S +
Sbjct: 62 --SRDRKRLRRSRSRERDRSRERRRSRS-----RDRRRSRSRSRGRRSRSSSPGNKSKKT 114
Query: 322 GSRSSSKKK 330
+RS SK+K
Sbjct: 115 ENRSRSKEK 123
Score = 73.6 bits (179), Expect = 2e-13
Identities = 59/142 (41%), Positives = 72/142 (50%), Gaps = 22/142 (15%)
Query: 195 KKKSNRRSRSKSRS-SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRG 253
+K+S R RS SRS S S S RS RSRSR R R S+SR + SR R R R
Sbjct: 9 RKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRL 68
Query: 254 SKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSP----- 308
+SRS R S R+RS S R+R+RSRSRS + RR+RS SP
Sbjct: 69 RRSRSRERDR---SRERRRSRS-------RDRRRSRSRS------RGRRSRSSSPGNKSK 112
Query: 309 ERRHRSSSGSSHSGSRSSSKKK 330
+ +RS S G SS +KK
Sbjct: 113 KTENRSRSKEKTDGGESSKEKK 134
Score = 72.8 bits (177), Expect = 4e-13
Identities = 58/142 (40%), Positives = 70/142 (49%), Gaps = 15/142 (10%)
Query: 195 KKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRS----RSRSRSSSSSQSRSRSSSRERSR 250
++ + R RS SR S S SRS SPS RS+ RSRSR + RSRS + RSR
Sbjct: 3 RESRHYRKRSASRG-RSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR 61
Query: 251 SRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRS-RSRSSSSGDR-KKRRTRSRSP 308
SR K SRS S +R S R+R R RSRSSS G++ KK RSRS
Sbjct: 62 SRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSK 121
Query: 309 ERRHRSSSGSSHSGSRSSSKKK 330
E+ + G S KKK
Sbjct: 122 EK--------TDGGESSKEKKK 135
Score = 65.9 bits (159), Expect = 5e-11
Identities = 40/121 (33%), Positives = 61/121 (50%), Gaps = 8/121 (6%)
Query: 188 SEEEDSNKKKSNRRSRSKSRS-----SHSRSSSRSSSPSSSR---SRSRSRSRSSSSSQS 239
S + +K+ +RRSRS+ R S SR RS S R SRSR R RS +S
Sbjct: 26 SPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRS 85
Query: 240 RSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRK 299
RSR R RSRSRG +SRSSS ++ + + + E ++++ + + +++
Sbjct: 86 RSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKE 145
Query: 300 K 300
K
Sbjct: 146 K 146
Score = 60.1 bits (144), Expect = 3e-09
Identities = 41/141 (29%), Positives = 56/141 (39%), Gaps = 3/141 (2%)
Query: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS---SSQSRSRSSSRERS 249
S R R R S SR R S SR + RSRSR S+SR R SRER
Sbjct: 24 SRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERR 83
Query: 250 RSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPE 309
RSR R S RG S + S + R+R + ++ S KK+ + E
Sbjct: 84 RSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDE 143
Query: 310 RRHRSSSGSSHSGSRSSSKKK 330
+ + + + K+K
Sbjct: 144 KEKDAGNFDQNKLEEEMRKRK 164
Score = 59.3 bits (142), Expect = 5e-09
Identities = 47/181 (25%), Positives = 72/181 (39%), Gaps = 20/181 (11%)
Query: 128 GRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDA 187
GR+ + YR K S S+ D+ D D + D
Sbjct: 2 GRESRHYR---------------KRSASRGRSGSRSRSRSPSDKRSKRGD-DRRSRSRDR 45
Query: 188 SEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSR----S 243
+ ++ + RRSRS+ R RS SR S R RSRSR R S S+SR R S
Sbjct: 46 DRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSS 105
Query: 244 SSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRT 303
S +S+ ++SRS ++ G SS K+ + + ++ + +KR+
Sbjct: 106 SPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKE 165
Query: 304 R 304
R
Sbjct: 166 R 166
Score = 51.6 bits (122), Expect = 1e-06
Identities = 39/182 (21%), Positives = 71/182 (39%), Gaps = 11/182 (6%)
Query: 109 RENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYK 168
RE+ Y +R S G R + ++ K +D+ S + D + S+ +
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRS-------KRGDDRRSRSRDRDRRRERSRSR 55
Query: 169 LDEDEDEDDADLSKYNL----DASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSR 224
D + + D S E ++ + RRSRS+SR SRSSS + +
Sbjct: 56 DKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTE 115
Query: 225 SRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERN 284
+RSRS+ ++ S+ + ++ K + ++ RKR E+
Sbjct: 116 NRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQR 175
Query: 285 RK 286
+K
Sbjct: 176 KK 177
Score = 50.8 bits (120), Expect = 2e-06
Identities = 48/180 (26%), Positives = 74/180 (41%), Gaps = 19/180 (10%)
Query: 129 RKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDAS 188
RK+ RG++ G S + DK S+ ++ + + E D S+
Sbjct: 9 RKRSASRGRS-GSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR------ 61
Query: 189 EEEDSNKKKSNRRSRSKSRS-SHSRSSSRSSSPSSSRSRSRSR-SRSSSSSQSRSRSSSR 246
S +K RRSRS+ R S R SRS SRSRSR R SRSSS ++ +R
Sbjct: 62 ----SRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENR 117
Query: 247 ERSRSR--GSKSRSSSRSHRGSSSPRKR----SYSSSSSSPERNRKRSRSRSSSSGDRKK 300
RS+ + G +S + + K ++ + E +++ R RKK
Sbjct: 118 SRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKK 177
Score = 33.1 bits (74), Expect = 0.35
Identities = 39/176 (22%), Positives = 68/176 (38%), Gaps = 23/176 (13%)
Query: 27 RRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRSECN 86
R S + + K TE + T+ G++ EK + D + K N +
Sbjct: 101 RSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFD-------- 152
Query: 87 MCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILK 146
KLEE +E VE E+ + G KK+ G L+
Sbjct: 153 ------QNKLEEEMR-----KRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLE 201
Query: 147 EVEDKESE-GEEEDEDEDLSKYKLDEDE---DEDDADLSKYNLDASEEEDSNKKKS 198
+ +D E + E E E ++ +LD + +E ++ K+N+ + + N+KKS
Sbjct: 202 DDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKS 257
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 79.7 bits (195), Expect = 3e-15
Identities = 57/139 (41%), Positives = 74/139 (53%), Gaps = 21/139 (15%)
Query: 201 RSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSS 260
RSR + SH+ SS+R RSRSRSRSR S++ RSRS+ R R SR S+SR
Sbjct: 556 RSRDRKPGSHASSSAR------RRSRSRSRSR---STRRRSRSTDRRRGGSRRSRSREKR 606
Query: 261 RSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSS----- 315
R R S+SP +SSSSS R R R + R +KK+R+RSR +R S
Sbjct: 607 RRRRRSASPPPA--TSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPA 664
Query: 316 -----SGSSHSGSRSSSKK 329
SGS+ G R S ++
Sbjct: 665 PAPPPSGSTSCGDRDSRRR 683
Score = 65.5 bits (158), Expect = 6e-11
Identities = 52/146 (35%), Positives = 69/146 (47%), Gaps = 23/146 (15%)
Query: 195 KKKSNRRSRSKSRSSHSRSSSRSSSPS---------SSRSRSRSRSRSSSSSQSRSRSSS 245
+KKS R + + + SSS + P+ S + RSR R S +S SS+
Sbjct: 516 RKKSRRERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPGSHAS-----SSA 570
Query: 246 RERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRS---SSSGDRKKRR 302
R RSRSR SRS S R S+ R+R S S S E+ R+R RS S ++S RR
Sbjct: 571 RRRSRSR---SRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSSSSSRR 627
Query: 303 TRSRSPERRHRSSSGSSHSGSRSSSK 328
R R +HR GS RS S+
Sbjct: 628 ERHRG---KHRDGGGSKKKKKRSRSR 650
Score = 61.2 bits (147), Expect = 1e-09
Identities = 50/143 (34%), Positives = 74/143 (51%), Gaps = 11/143 (7%)
Query: 195 KKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGS 254
+++ R RS S + ++ + P+ +SR R R RS + ++ S SSS +
Sbjct: 489 QRRERYRQRSPSPAPAPAPAAAAGPPTRKKSR-RERKRSGEAKEAAS-SSSGTQPAPPAP 546
Query: 255 KSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRS----SSSGDRKK---RRTRSRS 307
S S+ HR S RK +SSS+ R+R RSRSRS S S DR++ RR+RSR
Sbjct: 547 ASPWDSKKHR--SRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSRE 604
Query: 308 PERRHRSSSGSSHSGSRSSSKKK 330
RR R S+ + S SSS ++
Sbjct: 605 KRRRRRRSASPPPATSSSSSSRR 627
Score = 53.5 bits (127), Expect = 3e-07
Identities = 39/131 (29%), Positives = 56/131 (42%), Gaps = 3/131 (2%)
Query: 200 RRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSS 259
+R+ + R S S +P+SS R S + R SS++ R G+ S SS
Sbjct: 702 KRTITVGRLDKSDPRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSS 761
Query: 260 SRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSS 319
S +GS R+++ +R+R R R RSS K S P + SSGS
Sbjct: 762 SSREKGS---RRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSG 818
Query: 320 HSGSRSSSKKK 330
S S SS +
Sbjct: 819 SSSSSSSCSSR 829
Score = 43.5 bits (101), Expect = 3e-04
Identities = 35/109 (32%), Positives = 44/109 (40%), Gaps = 10/109 (9%)
Query: 198 SNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSR 257
S KS R S +SS SSSR + R + R R R+R RS K+R
Sbjct: 738 SGEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRS-SKKAR 796
Query: 258 SSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSR 306
S S P K SS S S S SSSS +K + +S+
Sbjct: 797 PPKESAPSSGPPPKPPVSSGSGS---------SSSSSSCSSRKVKLQSK 836
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/101 (33%), Positives = 41/101 (40%), Gaps = 9/101 (8%)
Query: 192 DSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRS 251
DS R S+ RS + SSS SS SR R + R R R+R R
Sbjct: 733 DSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSR---RKALDGGDRDRDRDRDRDRD 789
Query: 252 RGSKSRSSSRSHRGSSSPRKR------SYSSSSSSPERNRK 286
R SK + SS P + S SSSSSS +RK
Sbjct: 790 RSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSSCSSRK 830
Score = 40.0 bits (92), Expect = 0.003
Identities = 34/106 (32%), Positives = 50/106 (47%), Gaps = 12/106 (11%)
Query: 223 SRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPE 282
++ R R R RS S + + + +++ G +R SR R S K + SSSS +
Sbjct: 488 TQRRERYRQRSPSPAPAPAPAAAA------GPPTRKKSRRERKRSGEAKEAASSSSGT-- 539
Query: 283 RNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSK 328
+ + +S D KK R+R R P H SSS S SRS S+
Sbjct: 540 ---QPAPPAPASPWDSKKHRSRDRKPGS-HASSSARRRSRSRSRSR 581
Score = 37.4 bits (85), Expect = 0.019
Identities = 60/239 (25%), Positives = 88/239 (36%), Gaps = 46/239 (19%)
Query: 131 KKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEE 190
K RG + PAS K +SEG +E S K D A S +S E
Sbjct: 712 KSDPRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQK---DRRRSGAASSS---SSSRE 765
Query: 191 EDSNKK--------KSNRRSRSKSRSSHSRSSSRSSSPSSSR------SRSRSRSRSSSS 236
+ S +K + R R + RSS + S+PSS S S SSSS
Sbjct: 766 KGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSS 825
Query: 237 SQSR----------------SRSSSRERSRSRGSKSRSSSRSH-RGSSSP-----RKRSY 274
SR S ++ + + S G S S R S SP +
Sbjct: 826 CSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGSIGVKFSRDRESRSPFLKPDERAPT 885
Query: 275 SSSSSSPERNRKRSRSRSSSSGDRK----KRRTRSRSPERRHRSSSGSSHSGSRSSSKK 329
+ ++P + + + +G +K K +T+ ++ RS GS SG + S KK
Sbjct: 886 EMAKAAPGSTKPKKTKVKAKAGAKKTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKK 944
Score = 28.9 bits (63), Expect = 6.6
Identities = 15/41 (36%), Positives = 22/41 (53%)
Query: 123 EYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDED 163
+YD F A P+ +E E++E E EEEDE+E+
Sbjct: 247 KYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEE 287
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 79.7 bits (195), Expect = 3e-15
Identities = 72/256 (28%), Positives = 113/256 (44%), Gaps = 32/256 (12%)
Query: 101 GYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDE 160
GYG G +E E R + E + ++ ++R + A KE E + ++ +E
Sbjct: 390 GYGSGDSEDE------RSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEE 443
Query: 161 DEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSP 220
++ ++ E + + + +L + E D + +R+ +++ S
Sbjct: 444 EKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKE 503
Query: 221 SSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSS 280
RSRS S S SSSS SR+ S+S S S S S SSR+ SSSP+++ S S S
Sbjct: 504 KQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRS 563
Query: 281 PERNRKRSRSRSSS-----------------------SGDRKKRRTRSRSPERRH---RS 314
P +RSRSRS S S +R++RR RS S ERR RS
Sbjct: 564 PTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRS 623
Query: 315 SSGSSHSGSRSSSKKK 330
++ SRS S+ +
Sbjct: 624 RDRRTNRASRSRSRDR 639
Score = 77.0 bits (188), Expect = 2e-14
Identities = 66/228 (28%), Positives = 100/228 (43%), Gaps = 10/228 (4%)
Query: 108 ERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKY 167
E++ E + +E ++ + E +A G E K + E E ++
Sbjct: 444 EKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDV----VNEKKRTPNETTSVLEPKKEH 499
Query: 168 KLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRS 227
K E + + S +S S+ + S S S SR+SSRSSSP + S
Sbjct: 500 KEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHS 559
Query: 228 RSRSRSSSSSQSRSRSSSR----ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPER 283
RSRS + + +SRSRS SR E +R+R K R RS+R S +R S S R
Sbjct: 560 RSRSPTIKARRSRSRSYSRRIKIESNRAR-VKIRDRRRSNRNSIERERRRNRSPSRERRR 618
Query: 284 NRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGS-SHSGSRSSSKKK 330
+R RSR R ++ R + R R + ++R S S H G ++K
Sbjct: 619 SRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERK 666
Score = 76.6 bits (187), Expect = 3e-14
Identities = 65/256 (25%), Positives = 106/256 (41%), Gaps = 36/256 (14%)
Query: 108 ERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKY 167
E+ ++ +E E+DG+ +KK+ + KE ++KE +G
Sbjct: 462 EQNSLSLLEAREADGDVVN---EKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSS 518
Query: 168 KLDEDEDEDDADLSKYNLDASE------EEDSNKKKSNRRSRSKS-----RSSHSRSSSR 216
+ + +S + +S S+ K+ R SRS+S R S SRS SR
Sbjct: 519 SSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR 578
Query: 217 SSSPSSSRSR----------------SRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSS 260
S+R+R R R+RS S + RSRS SR+R +R S+SRS
Sbjct: 579 RIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRD 638
Query: 261 R----SHRGSSSPRKRSYSSSSSSPERNRKRSRS--RSSSSGDRKKRRTRSRSPERRHRS 314
R RG+ S + + ER ++RSRS + D+++ R + + E++ R
Sbjct: 639 RRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKRE 698
Query: 315 SSGSSHSGSRSSSKKK 330
S K+K
Sbjct: 699 EKDFKFSSQDDRLKRK 714
Score = 59.7 bits (143), Expect = 3e-09
Identities = 54/212 (25%), Positives = 85/212 (40%), Gaps = 12/212 (5%)
Query: 109 RENVEYIEREESDGEYD--EFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSK 166
R N IERE E R + + R + AS + + ++ + + + + K
Sbjct: 596 RSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHK 655
Query: 167 YKLDEDEDED--------DADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSS 218
+K + E E D D K + + E+D K+K R + SS R
Sbjct: 656 HKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKR 715
Query: 219 SPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSS 278
S R+ SRS S S + SR S++ + K S S R SS S +
Sbjct: 716 E--SERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKA 773
Query: 279 SSPERNRKRSRSRSSSSGDRKKRRTRSRSPER 310
P+ +R RS +S SG + R+ +S+S R
Sbjct: 774 KKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
Score = 47.8 bits (112), Expect = 1e-05
Identities = 44/161 (27%), Positives = 65/161 (40%), Gaps = 28/161 (17%)
Query: 190 EEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSR----------------- 232
E N+ S R RS+SRS R ++R +SRSRSR R +
Sbjct: 605 ERRRNRSPSRERRRSRSRS-RDRRTNR-----ASRSRSRDRRKIDDQRGNLSGNSHKHKG 658
Query: 233 -SSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPR-KRSYSSSSSSPERNRKRSRS 290
+ + + RS S ++ R + K R + R R ++ + SS RKR
Sbjct: 659 EAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESE 718
Query: 291 RS---SSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSK 328
R+ S S K R SR ++ + HSGS SS +
Sbjct: 719 RTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGR 759
Score = 42.4 bits (98), Expect = 6e-04
Identities = 63/280 (22%), Positives = 109/280 (38%), Gaps = 58/280 (20%)
Query: 108 ERENVEYIEREESDGEYDEFGRKKKKYRGKAV-GPASILKEVEDKESEGEEEDED----- 161
ERE + +E+E + + + +K+KK A G L + +S+ EEED +
Sbjct: 244 EREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAA 303
Query: 162 --------------EDLSKYKLDEDEDE------DDADLSKYNLDASEEE------DSNK 195
E+ S ++ E+E E L++ LD ++EE D+++
Sbjct: 304 SSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHR 363
Query: 196 KKSNRRSRSKSRSSHSRSSS------RSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERS 249
K + ++ ++SS S + S S RS S SS + R R++
Sbjct: 364 KATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQ 423
Query: 250 RSRGSKSRSSSRSHRGSSSPRKRSYSSSSSS------PERNRKRSRSRSSSSGD--RKKR 301
+ K + H K+ + E+N + GD +K+
Sbjct: 424 EAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKK 483
Query: 302 RTRSRS-----PERRH-------RSSSGSSHSGSRSSSKK 329
RT + + P++ H RS SGSS SGS SS+ +
Sbjct: 484 RTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSR 523
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 79.7 bits (195), Expect = 3e-15
Identities = 72/256 (28%), Positives = 113/256 (44%), Gaps = 32/256 (12%)
Query: 101 GYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDE 160
GYG G +E E R + E + ++ ++R + A KE E + ++ +E
Sbjct: 390 GYGSGDSEDE------RSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEE 443
Query: 161 DEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSP 220
++ ++ E + + + +L + E D + +R+ +++ S
Sbjct: 444 EKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKE 503
Query: 221 SSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSS 280
RSRS S S SSSS SR+ S+S S S S S SSR+ SSSP+++ S S S
Sbjct: 504 KQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRS 563
Query: 281 PERNRKRSRSRSSS-----------------------SGDRKKRRTRSRSPERRH---RS 314
P +RSRSRS S S +R++RR RS S ERR RS
Sbjct: 564 PTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRS 623
Query: 315 SSGSSHSGSRSSSKKK 330
++ SRS S+ +
Sbjct: 624 RDRRTNRASRSRSRDR 639
Score = 77.0 bits (188), Expect = 2e-14
Identities = 66/228 (28%), Positives = 100/228 (43%), Gaps = 10/228 (4%)
Query: 108 ERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKY 167
E++ E + +E ++ + E +A G E K + E E ++
Sbjct: 444 EKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDV----VNEKKRTPNETTSVLEPKKEH 499
Query: 168 KLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRS 227
K E + + S +S S+ + S S S SR+SSRSSSP + S
Sbjct: 500 KEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHS 559
Query: 228 RSRSRSSSSSQSRSRSSSR----ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPER 283
RSRS + + +SRSRS SR E +R+R K R RS+R S +R S S R
Sbjct: 560 RSRSPTIKARRSRSRSYSRRIKIESNRAR-VKIRDRRRSNRNSIERERRRNRSPSRERRR 618
Query: 284 NRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGS-SHSGSRSSSKKK 330
+R RSR R ++ R + R R + ++R S S H G ++K
Sbjct: 619 SRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERK 666
Score = 76.6 bits (187), Expect = 3e-14
Identities = 65/256 (25%), Positives = 106/256 (41%), Gaps = 36/256 (14%)
Query: 108 ERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKY 167
E+ ++ +E E+DG+ +KK+ + KE ++KE +G
Sbjct: 462 EQNSLSLLEAREADGDVVN---EKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSS 518
Query: 168 KLDEDEDEDDADLSKYNLDASE------EEDSNKKKSNRRSRSKS-----RSSHSRSSSR 216
+ + +S + +S S+ K+ R SRS+S R S SRS SR
Sbjct: 519 SSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR 578
Query: 217 SSSPSSSRSR----------------SRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSS 260
S+R+R R R+RS S + RSRS SR+R +R S+SRS
Sbjct: 579 RIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRD 638
Query: 261 R----SHRGSSSPRKRSYSSSSSSPERNRKRSRS--RSSSSGDRKKRRTRSRSPERRHRS 314
R RG+ S + + ER ++RSRS + D+++ R + + E++ R
Sbjct: 639 RRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKRE 698
Query: 315 SSGSSHSGSRSSSKKK 330
S K+K
Sbjct: 699 EKDFKFSSQDDRLKRK 714
Score = 59.7 bits (143), Expect = 3e-09
Identities = 54/212 (25%), Positives = 85/212 (40%), Gaps = 12/212 (5%)
Query: 109 RENVEYIEREESDGEYD--EFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSK 166
R N IERE E R + + R + AS + + ++ + + + + K
Sbjct: 596 RSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHK 655
Query: 167 YKLDEDEDED--------DADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSS 218
+K + E E D D K + + E+D K+K R + SS R
Sbjct: 656 HKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKR 715
Query: 219 SPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSS 278
S R+ SRS S S + SR S++ + K S S R SS S +
Sbjct: 716 E--SERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKA 773
Query: 279 SSPERNRKRSRSRSSSSGDRKKRRTRSRSPER 310
P+ +R RS +S SG + R+ +S+S R
Sbjct: 774 KKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
Score = 47.8 bits (112), Expect = 1e-05
Identities = 44/161 (27%), Positives = 65/161 (40%), Gaps = 28/161 (17%)
Query: 190 EEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSR----------------- 232
E N+ S R RS+SRS R ++R +SRSRSR R +
Sbjct: 605 ERRRNRSPSRERRRSRSRS-RDRRTNR-----ASRSRSRDRRKIDDQRGNLSGNSHKHKG 658
Query: 233 -SSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPR-KRSYSSSSSSPERNRKRSRS 290
+ + + RS S ++ R + K R + R R ++ + SS RKR
Sbjct: 659 EAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESE 718
Query: 291 RS---SSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSK 328
R+ S S K R SR ++ + HSGS SS +
Sbjct: 719 RTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGR 759
Score = 42.4 bits (98), Expect = 6e-04
Identities = 63/280 (22%), Positives = 109/280 (38%), Gaps = 58/280 (20%)
Query: 108 ERENVEYIEREESDGEYDEFGRKKKKYRGKAV-GPASILKEVEDKESEGEEEDED----- 161
ERE + +E+E + + + +K+KK A G L + +S+ EEED +
Sbjct: 244 EREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAA 303
Query: 162 --------------EDLSKYKLDEDEDE------DDADLSKYNLDASEEE------DSNK 195
E+ S ++ E+E E L++ LD ++EE D+++
Sbjct: 304 SSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHR 363
Query: 196 KKSNRRSRSKSRSSHSRSSS------RSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERS 249
K + ++ ++SS S + S S RS S SS + R R++
Sbjct: 364 KATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQ 423
Query: 250 RSRGSKSRSSSRSHRGSSSPRKRSYSSSSSS------PERNRKRSRSRSSSSGD--RKKR 301
+ K + H K+ + E+N + GD +K+
Sbjct: 424 EAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKK 483
Query: 302 RTRSRS-----PERRH-------RSSSGSSHSGSRSSSKK 329
RT + + P++ H RS SGSS SGS SS+ +
Sbjct: 484 RTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSR 523
>gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens]
Length = 272
Score = 79.3 bits (194), Expect = 4e-15
Identities = 63/118 (53%), Positives = 74/118 (62%), Gaps = 17/118 (14%)
Query: 190 EEDSNKKKSNRRSR---SKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSR 246
E+ S K+ + R+ + R S SRS SRS + SSSRSRSRSRSRS +S SRS SR
Sbjct: 162 EKLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSR---KSYSRSRSR 218
Query: 247 ERSRSRGSKSRSSSRS-------HRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGD 297
RSRSR SKSRS SRS RGSSS RS S +S +R+R RSRSRS SG+
Sbjct: 219 SRSRSR-SKSRSVSRSPVPEKSQKRGSSS---RSKSPASVDRQRSRSRSRSRSVDSGN 272
Score = 73.6 bits (179), Expect = 2e-13
Identities = 53/92 (57%), Positives = 64/92 (69%), Gaps = 9/92 (9%)
Query: 219 SPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSS 278
S SRSRSRSRSR+ SSS+SRSRS RSRSR S SRS SRS R S + RS S S
Sbjct: 180 SKRHSRSRSRSRSRTRSSSRSRSRS----RSRSRKSYSRSRSRS-RSRSRSKSRSV-SRS 233
Query: 279 SSPERNRKR---SRSRSSSSGDRKKRRTRSRS 307
PE+++KR SRS+S +S DR++ R+RSRS
Sbjct: 234 PVPEKSQKRGSSSRSKSPASVDRQRSRSRSRS 265
Score = 52.4 bits (124), Expect = 6e-07
Identities = 38/78 (48%), Positives = 43/78 (55%), Gaps = 14/78 (17%)
Query: 188 SEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRS--------RSSSS--- 236
S + +S RSRS+SR S+SRS SRS S S S+SRS SRS R SSS
Sbjct: 190 SRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSK 249
Query: 237 ---SQSRSRSSSRERSRS 251
S R RS SR RSRS
Sbjct: 250 SPASVDRQRSRSRSRSRS 267
Score = 49.7 bits (117), Expect = 4e-06
Identities = 41/94 (43%), Positives = 45/94 (47%), Gaps = 9/94 (9%)
Query: 235 SSSQSRSRSSSRERSRSRGSKSRSSSRSH-RGSSSPRKRSYSSSSSSPERNRKRSRSRSS 293
S + R R S+SRS SRS R SS R RS S S S R+R RSRSRS
Sbjct: 165 SGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRS- 223
Query: 294 SSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
R K R+ SRSP GSS SRS S
Sbjct: 224 ----RSKSRSVSRSPVPEKSQKRGSS---SRSKS 250
Score = 49.3 bits (116), Expect = 5e-06
Identities = 66/241 (27%), Positives = 89/241 (36%), Gaps = 54/241 (22%)
Query: 139 VGPASILKEVEDKESEGEEEDEDEDLSK-YKLDEDEDEDDADLSKYNLDASEEEDSNKKK 197
+ PA+ K+VE + +G D DL + + E ED DAD + Y LD E
Sbjct: 11 LNPAAREKDVE-RFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTI 69
Query: 198 SNRRSRSKSRSSHSRSSSRSSS--PSSSRS-----RSRSRSRSSSSSQSRSRSSSRERSR 250
+ R+RS+ R S R SS P + R R+ +R + S S ++ R
Sbjct: 70 EHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMR 129
Query: 251 SRGSKS------------------------------------------RSSSRSHRGSSS 268
G + S R R S
Sbjct: 130 QAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSR 189
Query: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSK 328
R R+ SSS S R+R RSRSR S S R + R+RSRS R S S R SS
Sbjct: 190 SRSRTRSSSRS---RSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSS 246
Query: 329 K 329
+
Sbjct: 247 R 247
>gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens]
Length = 272
Score = 79.3 bits (194), Expect = 4e-15
Identities = 63/118 (53%), Positives = 74/118 (62%), Gaps = 17/118 (14%)
Query: 190 EEDSNKKKSNRRSR---SKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSR 246
E+ S K+ + R+ + R S SRS SRS + SSSRSRSRSRSRS +S SRS SR
Sbjct: 162 EKLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSR---KSYSRSRSR 218
Query: 247 ERSRSRGSKSRSSSRS-------HRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGD 297
RSRSR SKSRS SRS RGSSS RS S +S +R+R RSRSRS SG+
Sbjct: 219 SRSRSR-SKSRSVSRSPVPEKSQKRGSSS---RSKSPASVDRQRSRSRSRSRSVDSGN 272
Score = 73.6 bits (179), Expect = 2e-13
Identities = 53/92 (57%), Positives = 64/92 (69%), Gaps = 9/92 (9%)
Query: 219 SPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSS 278
S SRSRSRSRSR+ SSS+SRSRS RSRSR S SRS SRS R S + RS S S
Sbjct: 180 SKRHSRSRSRSRSRTRSSSRSRSRS----RSRSRKSYSRSRSRS-RSRSRSKSRSV-SRS 233
Query: 279 SSPERNRKR---SRSRSSSSGDRKKRRTRSRS 307
PE+++KR SRS+S +S DR++ R+RSRS
Sbjct: 234 PVPEKSQKRGSSSRSKSPASVDRQRSRSRSRS 265
Score = 52.4 bits (124), Expect = 6e-07
Identities = 38/78 (48%), Positives = 43/78 (55%), Gaps = 14/78 (17%)
Query: 188 SEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRS--------RSSSS--- 236
S + +S RSRS+SR S+SRS SRS S S S+SRS SRS R SSS
Sbjct: 190 SRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSK 249
Query: 237 ---SQSRSRSSSRERSRS 251
S R RS SR RSRS
Sbjct: 250 SPASVDRQRSRSRSRSRS 267
Score = 49.7 bits (117), Expect = 4e-06
Identities = 41/94 (43%), Positives = 45/94 (47%), Gaps = 9/94 (9%)
Query: 235 SSSQSRSRSSSRERSRSRGSKSRSSSRSH-RGSSSPRKRSYSSSSSSPERNRKRSRSRSS 293
S + R R S+SRS SRS R SS R RS S S S R+R RSRSRS
Sbjct: 165 SGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRS- 223
Query: 294 SSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
R K R+ SRSP GSS SRS S
Sbjct: 224 ----RSKSRSVSRSPVPEKSQKRGSS---SRSKS 250
Score = 49.3 bits (116), Expect = 5e-06
Identities = 66/241 (27%), Positives = 89/241 (36%), Gaps = 54/241 (22%)
Query: 139 VGPASILKEVEDKESEGEEEDEDEDLSK-YKLDEDEDEDDADLSKYNLDASEEEDSNKKK 197
+ PA+ K+VE + +G D DL + + E ED DAD + Y LD E
Sbjct: 11 LNPAAREKDVE-RFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTI 69
Query: 198 SNRRSRSKSRSSHSRSSSRSSS--PSSSRS-----RSRSRSRSSSSSQSRSRSSSRERSR 250
+ R+RS+ R S R SS P + R R+ +R + S S ++ R
Sbjct: 70 EHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMR 129
Query: 251 SRGSKS------------------------------------------RSSSRSHRGSSS 268
G + S R R S
Sbjct: 130 QAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSR 189
Query: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSK 328
R R+ SSS S R+R RSRSR S S R + R+RSRS R S S R SS
Sbjct: 190 SRSRTRSSSRS---RSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSS 246
Query: 329 K 329
+
Sbjct: 247 R 247
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 78.6 bits (192), Expect = 7e-15
Identities = 70/236 (29%), Positives = 101/236 (42%), Gaps = 39/236 (16%)
Query: 121 DGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADL 180
+ E D+ + K K R K+ + ++ + KE + + +E + + + E
Sbjct: 441 NSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHE----- 495
Query: 181 SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSS-----RSRSRSR----S 231
N+ E++ +K K RSRSK +S S S S S R++SRSR +
Sbjct: 496 ---NVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDIT 552
Query: 232 RSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSR 291
+ S SR+R SR R RSR +SR+ R R + Y R R RSRSR
Sbjct: 553 KGKHSYNSRTRERSRSRDRSRRVRSRTHDRDR-----SRSKEYHRYREQEYRRRGRSRSR 607
Query: 292 S-------SSSGDRKKRRTRSRSPERRHRSS----------SGSSHSGSRSSSKKK 330
S S DR++RR SRS ER S S SSH S S+K+
Sbjct: 608 ERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKR 663
Score = 73.9 bits (180), Expect = 2e-13
Identities = 57/203 (28%), Positives = 88/203 (43%), Gaps = 19/203 (9%)
Query: 146 KEVEDKESEGEEED-----EDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNR 200
K+V+D +S +E D E +D K K+ + SK + E + + + +
Sbjct: 424 KKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEK 483
Query: 201 RSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSS-QSRSRSSSRERSRSRGSKSRSS 259
R RS+S+ + S S+ + + RSRS S Q S+S+ + S+S+ R+
Sbjct: 484 RMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQ 543
Query: 260 SRS---------HRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKR----RTRSR 306
SRS H +S R+RS S S R+R R RS S + R R R R
Sbjct: 544 SRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGR 603
Query: 307 SPERRHRSSSGSSHSGSRSSSKK 329
S R R+ G S S R ++
Sbjct: 604 SRSRERRTPPGRSRSKDRRRRRR 626
Score = 73.9 bits (180), Expect = 2e-13
Identities = 62/231 (26%), Positives = 104/231 (45%), Gaps = 21/231 (9%)
Query: 108 ERENVEYIERE-ESDGEYDEFGRKKKKYRG-KAVGPASILKEVEDKESEGEEEDEDEDLS 165
+ ENV+ E++ +S G+ E R K+K + ++ + ++K+ + + D++
Sbjct: 493 DHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDIT 552
Query: 166 K----YKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKS--RSSHSRSSSRSSS 219
K Y E D S+ + + D ++ K R R + R SRS R +
Sbjct: 553 KGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTP 612
Query: 220 PSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSS 279
P SRS+ R R R S S R S SR + + R +S+SS R + +S KR YS
Sbjct: 613 PGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHR--KENSESEKRMYS---- 666
Query: 280 SPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
+SR +SS+ R+K+ R +SP + + SS + S K+
Sbjct: 667 -------KSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKE 710
Score = 73.6 bits (179), Expect = 2e-13
Identities = 57/229 (24%), Positives = 104/229 (45%), Gaps = 25/229 (10%)
Query: 113 EYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDED 172
E + +E D +++ K+ + R K ++ ++ + +S+G++++ K K E
Sbjct: 466 EKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLES 525
Query: 173 EDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS---SHSRSSSRSSSPSSSRSRSRS 229
+ ++E + S K+ +RR++S+SR + + S S + SRSR RS
Sbjct: 526 K-------------SNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRS 572
Query: 230 R---SRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHR------GSSSPRKRSYSSSSSS 280
R SR+ +SRS+ R R + + RS SR R S R+R S SS
Sbjct: 573 RRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSE 632
Query: 281 PERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKK 329
E ++ R++ + + + R + E+R S S +S + S KK
Sbjct: 633 REESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKK 681
Score = 68.9 bits (167), Expect = 6e-12
Identities = 56/195 (28%), Positives = 92/195 (47%), Gaps = 20/195 (10%)
Query: 146 KEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSK 205
+++ D + E + + K D + + D+ + SE++D K K +R++SK
Sbjct: 404 RKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRN----SEKDDKYKNKVKKRAKSK 459
Query: 206 SRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRG 265
SRS S+ S+S S +R+ + R S S+ R + +E+ + SK + RS
Sbjct: 460 SRSK-SKEKSKSKERDSKHNRNEEK-RMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSK 517
Query: 266 SSSPRKRSYSSS---SSSPERNRK-RSRSR-------SSSSGDRKKRRTRSRSPERRHRS 314
S + S S+ S S E++R+ +SRSR S R + R+RSR RR RS
Sbjct: 518 EKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRS 577
Query: 315 SSGSSHSGSRSSSKK 329
+H RS SK+
Sbjct: 578 ---RTHDRDRSRSKE 589
Score = 61.2 bits (147), Expect = 1e-09
Identities = 44/130 (33%), Positives = 61/130 (46%), Gaps = 21/130 (16%)
Query: 201 RSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSS 260
+S+ K SS SSS SSS S S S S+SSS S S S S++ E+S+ R K R +S
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDS-SDSESATEEKSKKRKKKHRKNS 238
Query: 261 RSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSS--------------------SSGDRKK 300
R H+ RK+S S+SS E ++ +S+ D K+
Sbjct: 239 RKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKE 298
Query: 301 RRTRSRSPER 310
R+ R R ER
Sbjct: 299 RKNRERERER 308
Score = 52.8 bits (125), Expect = 4e-07
Identities = 45/221 (20%), Positives = 81/221 (36%), Gaps = 9/221 (4%)
Query: 102 YGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDED 161
+G + +E V IE +++D F + G+ + + + KE + +
Sbjct: 141 FGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSS 200
Query: 162 EDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPS 221
S D D +D E+ KKK + SR + R S+ S+ S
Sbjct: 201 SSDSDSSSDSQSSSDSSDSESAT---EEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASS 257
Query: 222 SSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSP 281
S + + S+ R R S ++ + + R+R + +S P
Sbjct: 258 ESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQP 317
Query: 282 ERNRK-----RSRSRSSSSGDRKKRR-TRSRSPERRHRSSS 316
++ RS + G R+ R +RSRS +R RS +
Sbjct: 318 ASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSET 358
Score = 51.6 bits (122), Expect = 1e-06
Identities = 36/163 (22%), Positives = 73/163 (44%), Gaps = 13/163 (7%)
Query: 166 KYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRS 225
K +L+E ++ + + ++ + ++ + + + K H +S +S
Sbjct: 385 KSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEK 444
Query: 226 RSRSRSRSSSSSQSRSRSSSRERSRS--RGSK----------SRSSSRSHRGSSSPRKRS 273
+ +++ ++S+SRS S+E+S+S R SK SRS R H K+S
Sbjct: 445 DDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQS 504
Query: 274 YSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSS 316
S ER+R + +S+ S + ++S+ +RR +S S
Sbjct: 505 -DSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRS 546
Score = 47.4 bits (111), Expect = 2e-05
Identities = 54/243 (22%), Positives = 98/243 (40%), Gaps = 42/243 (17%)
Query: 129 RKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDL-----SKYKLDEDEDEDDADLSKY 183
+K+KK R K+ AS E E+ E++ + E++ +++ + + + D + +
Sbjct: 242 KKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKAD-EKERK 300
Query: 184 NLDASEEEDSNKKKSNRRSRSK-------SRSSHSRSSSRSSSPSSSRSRSRSRS----- 231
N + E + N S S + R R R +PS SRSR R R
Sbjct: 301 NRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPP 360
Query: 232 --RSSSSSQSRSRSSSRER----SRSRGSKSRSSSRS-----------HRG-SSSPRKRS 273
R R R SS ER +S ++ + + RS HR S SP +++
Sbjct: 361 HWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKN 420
Query: 274 YSSS------SSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
S+S ER+ +R+ + ++ K+R +S+S + S + +
Sbjct: 421 EKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRN 480
Query: 328 KKK 330
++K
Sbjct: 481 EEK 483
Score = 47.0 bits (110), Expect = 2e-05
Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 5/122 (4%)
Query: 187 ASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSR 246
+SE E+S + ++ +S+SSH + +S S S+SR +SS+ SR + + R
Sbjct: 630 SSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDH-----NSSNNSREKKADR 684
Query: 247 ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSR 306
++S K S + S K SS + N+K + ++ K+
Sbjct: 685 DQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHES 744
Query: 307 SP 308
SP
Sbjct: 745 SP 746
Score = 42.0 bits (97), Expect = 8e-04
Identities = 29/119 (24%), Positives = 55/119 (46%), Gaps = 3/119 (2%)
Query: 212 RSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRK 271
R + ++S+ + R S +S+ E+ R + S S SSS S SSS +
Sbjct: 152 REIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQ 211
Query: 272 RSYSSS---SSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
S SS S++ E+++KR + +S KK + + + ++ S S + + ++ S
Sbjct: 212 SSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQS 270
Score = 35.8 bits (81), Expect = 0.054
Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 257 RSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDR-KKRRTRSRSPERRHRSS 315
+ + H+ SSS S S SSS ++ S S++ ++ KKR+ + R R+H+
Sbjct: 185 KEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKE 244
Query: 316 SGSSHSGSRSSSKK 329
+S+S +
Sbjct: 245 KKKRKKSKKSASSE 258
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.302 0.117 0.316
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,054,547
Number of Sequences: 37866
Number of extensions: 678321
Number of successful extensions: 41962
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1283
Number of HSP's successfully gapped in prelim test: 1061
Number of HSP's that attempted gapping in prelim test: 7866
Number of HSP's gapped (non-prelim): 14032
length of query: 330
length of database: 18,247,518
effective HSP length: 103
effective length of query: 227
effective length of database: 14,347,320
effective search space: 3256841640
effective search space used: 3256841640
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.