Guide to the Human Genome
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Search of human proteins with 126157477

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|126157477 hypothetical protein LOC79680 [Homo sapiens]
         (364 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|126157477 hypothetical protein LOC79680 [Homo sapiens]             766   0.0  
gi|49355807 leucine zipper, down-regulated in cancer 1-like [Hom...    59   5e-09
gi|118200335 family with sequence similarity 127, member A [Homo...    54   2e-07
gi|33286446 opioid growth factor receptor [Homo sapiens]               54   3e-07
gi|6912480 leucine zipper, down-regulated in cancer 1 [Homo sapi...    54   3e-07
gi|146134388 YLP motif containing 1 [Homo sapiens]                     52   8e-07
gi|94421473 paternally expressed 10 isoform RF1 [Homo sapiens]         52   1e-06
gi|94421475 paternally expressed 10 isoform RF1/2 [Homo sapiens]       52   1e-06
gi|118200333 family with sequence similarity 127, member B isofo...    52   1e-06
gi|118200337 family with sequence similarity 127, member C [Homo...    52   1e-06
gi|239757911 PREDICTED: similar to Family with sequence similari...    50   2e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   49   7e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   49   7e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   49   7e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    49   7e-06
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             48   1e-05
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             48   1e-05
gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s...    48   2e-05
gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ...    48   2e-05
gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ...    48   2e-05
gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo s...    48   2e-05
gi|150170670 piccolo isoform 2 [Homo sapiens]                          47   2e-05
gi|150378539 piccolo isoform 1 [Homo sapiens]                          47   2e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    47   2e-05
gi|22749387 zinc finger, CCHC domain containing 5 [Homo sapiens]       47   3e-05
gi|167614488 TBC1 domain family, member 10B [Homo sapiens]             46   5e-05
gi|47132519 Ras association and pleckstrin homology domains 1 is...    46   6e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    45   8e-05
gi|194239681 tubulin tyrosine ligase-like family, member 10 isof...    45   8e-05
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              45   8e-05

>gi|126157477 hypothetical protein LOC79680 [Homo sapiens]
          Length = 364

 Score =  766 bits (1977), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 1   MPRGRCRQQGPRIPIWAAANYANAHPWQQMDKASPGVAYTPLVDPWIERPCCGDTVCVRT 60
           MPRGRCRQQGPRIPIWAAANYANAHPWQQMDKASPGVAYTPLVDPWIERPCCGDTVCVRT
Sbjct: 1   MPRGRCRQQGPRIPIWAAANYANAHPWQQMDKASPGVAYTPLVDPWIERPCCGDTVCVRT 60

Query: 61  TMEQKSTASGTCGGKPAERGPLAGHMPSSRPHRVDFCWVPGSDPGTFDGSPWLLDRFLAQ 120
           TMEQKSTASGTCGGKPAERGPLAGHMPSSRPHRVDFCWVPGSDPGTFDGSPWLLDRFLAQ
Sbjct: 61  TMEQKSTASGTCGGKPAERGPLAGHMPSSRPHRVDFCWVPGSDPGTFDGSPWLLDRFLAQ 120

Query: 121 LGDYMSFHFEHYQDNISRVCEILRRLTGRAQAWAAPYLDGDLPLPDDYELFCQDLKEVVQ 180
           LGDYMSFHFEHYQDNISRVCEILRRLTGRAQAWAAPYLDGDLPLPDDYELFCQDLKEVVQ
Sbjct: 121 LGDYMSFHFEHYQDNISRVCEILRRLTGRAQAWAAPYLDGDLPLPDDYELFCQDLKEVVQ 180

Query: 181 DPNSFAEYHAVVTCPLPLASSQLPVAPQLPVVRQYLARFLEGLALDMGTAPRSLPAAMAT 240
           DPNSFAEYHAVVTCPLPLASSQLPVAPQLPVVRQYLARFLEGLALDMGTAPRSLPAAMAT
Sbjct: 181 DPNSFAEYHAVVTCPLPLASSQLPVAPQLPVVRQYLARFLEGLALDMGTAPRSLPAAMAT 240

Query: 241 PAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPTPV 300
           PAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPTPV
Sbjct: 241 PAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPTPV 300

Query: 301 PRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEPPL 360
           PRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEPPL
Sbjct: 301 PRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEPPL 360

Query: 361 SPGF 364
           SPGF
Sbjct: 361 SPGF 364


>gi|49355807 leucine zipper, down-regulated in cancer 1-like [Homo
           sapiens]
          Length = 239

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 29/83 (34%), Positives = 43/83 (51%)

Query: 100 PGSDPGTFDGSPWLLDRFLAQLGDYMSFHFEHYQDNISRVCEILRRLTGRAQAWAAPYLD 159
           P S P  F G P  L  FL Q+  +M F    +     RV  ++ RLTG A+ WA P++ 
Sbjct: 98  PTSLPEPFSGDPGRLAGFLMQMDRFMIFQASRFPGEAERVAFLVSRLTGEAEKWAIPHMQ 157

Query: 160 GDLPLPDDYELFCQDLKEVVQDP 182
            D PL ++Y+ F  +L+   + P
Sbjct: 158 PDSPLRNNYQGFLAELRRTYKSP 180


>gi|118200335 family with sequence similarity 127, member A [Homo
           sapiens]
          Length = 113

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 27/75 (36%), Positives = 38/75 (50%)

Query: 104 PGTFDGSPWLLDRFLAQLGDYMSFHFEHYQDNISRVCEILRRLTGRAQAWAAPYLDGDLP 163
           P TFDG    L  F+ Q G YM      +  +  +V  ++ RLTG A  W  PY+  + P
Sbjct: 30  PETFDGDTDRLPEFIVQTGSYMFVDENTFSSDALKVTFLITRLTGPALQWVIPYIKKESP 89

Query: 164 LPDDYELFCQDLKEV 178
           L +DY  F  ++K V
Sbjct: 90  LLNDYRGFLAEMKRV 104


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 42/134 (31%), Positives = 55/134 (41%), Gaps = 12/134 (8%)

Query: 240 TPAVSGSNSVSRSALFEQQLTKESTPGPK-------EPPVLPSSTCSSKP-GPV--EPAS 289
           +P+ +   S +  A  E   +   TPGP+       EP   PS T   +P GP   EPA 
Sbjct: 517 SPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAE 576

Query: 290 SQPEEAAPTPV-PRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEV 348
           S  E   P+P  P   E A  P++ P P  P GP   +  E   ET G +       +  
Sbjct: 577 SPSETPGPSPAGPTRDEPAESPSETPGP-RPAGPAGDEPAESPSETPGPRPAGPAGDEPA 635

Query: 349 VEAPETPGEPPLSP 362
               ETPG  P  P
Sbjct: 636 ESPSETPGPSPAGP 649



 Score = 29.3 bits (64), Expect = 5.8
 Identities = 21/82 (25%), Positives = 35/82 (42%), Gaps = 11/82 (13%)

Query: 257 QQLTKESTPG-PKEPPVLPSSTCSSK---------PGPVEPASSQPEEAAPTPVPRLSES 306
           +++ +E +PG P         TC  +          GP +P S +P++A P    +  E+
Sbjct: 308 RKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGP-QPRSVEPQDAGPLERSQGDEA 366

Query: 307 ANPPAQRPDPAHPGGPKPQKTE 328
                 RP+P  P   K +K E
Sbjct: 367 GGHGEDRPEPLSPKESKKRKLE 388


>gi|6912480 leucine zipper, down-regulated in cancer 1 [Homo
           sapiens]
          Length = 146

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 2/88 (2%)

Query: 90  RPHRVDFCWVPGSDPGTFDGSPWLLDRFLAQLGDYMSFHFEHYQDNISRVCEILRRLTGR 149
           R  R   C VP   P TF+G    L  F+ Q   YM  +   + ++  +V  ++  LTG 
Sbjct: 42  RQVRPPSCPVPF--PETFNGESSRLPEFIVQTASYMLVNENRFCNDAMKVAFLISLLTGE 99

Query: 150 AQAWAAPYLDGDLPLPDDYELFCQDLKE 177
           A+ W  PY++ D P+  DY  F  ++K+
Sbjct: 100 AEEWVVPYIEMDSPILGDYRAFLDEMKQ 127


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 61/194 (31%), Positives = 72/194 (37%), Gaps = 36/194 (18%)

Query: 182 PNSFAEYHAVVTCPLPLASSQLPVAPQL---PVVRQYLARFLEGLALDMGTAPRSLPAAM 238
           P  F  Y  +   P PL +   PV P     PV+   L   +    +     P SLP ++
Sbjct: 517 PPPFVPYSQM---PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSV 573

Query: 239 ATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSK-PGPVEPASSQPEEAAP 297
             P +  S S               + GP  PPVLP  + SS  P PV P  S    A P
Sbjct: 574 PPPGMPPSLS---------------SAGP--PPVLPPPSLSSAGPPPVLPPPSLSSTAPP 616

Query: 298 T--PVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQE---------VSLGTPQ 346
              P+P LS SA PP   P P  P G  PQ T   V      Q            L TP 
Sbjct: 617 PVMPLPPLS-SATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPV 675

Query: 347 EVVEAPETPGEPPL 360
               AP T   PPL
Sbjct: 676 SFGSAPPTTYHPPL 689



 Score = 36.2 bits (82), Expect = 0.047
 Identities = 31/101 (30%), Positives = 42/101 (41%), Gaps = 8/101 (7%)

Query: 230 APRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPAS 289
           AP   P+ M TP         +  L  QQ TK   PG K+ PV+   T    P PV+   
Sbjct: 280 APEPDPSTM-TPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDT----PEPVKEEV 334

Query: 290 SQPEEAAPTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEE 330
           + P   A + VP    S  PP   P+   P    P++ + E
Sbjct: 335 TVP---ATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSE 372



 Score = 32.7 bits (73), Expect = 0.52
 Identities = 43/180 (23%), Positives = 62/180 (34%), Gaps = 55/180 (30%)

Query: 230 APRSLPAAMATPAVSGSNSVSRSALFEQQL----------------TKESTPGPKEPPVL 273
           +P S      TP+ S S+S S+S L   Q                 +K     P  P   
Sbjct: 194 SPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAP 253

Query: 274 PSSTCSSKPGPVEPA----SSQPEEAAPTPVPRLSESANPPAQRPD-------------- 315
           P +  + +  P+E      S++ ++AAP P P    S   P ++                
Sbjct: 254 PGNKTTVQQEPLESGAKNKSTEQQQAAPEPDP----STMTPQEQQQYWYRQHLLSLQQRT 309

Query: 316 ----PAHPGGP-----KPQKTEEEVL--------ETEGDQEVSLGTPQEVVEAPETPGEP 358
               P H  GP      P+  +EEV         E+   +E  L  P E V  P  P EP
Sbjct: 310 KVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEP 369



 Score = 29.3 bits (64), Expect = 5.8
 Identities = 26/92 (28%), Positives = 30/92 (32%), Gaps = 9/92 (9%)

Query: 280 SKPGPVEPASSQPEEAAPTPVPRLSESANP-------PAQRPDPAHPGGPKPQKTEEEVL 332
           S P P  P S  P      P P L  S  P       PA  P P  P    P      V 
Sbjct: 515 SMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVP 574

Query: 333 ETEGDQEVSLGTPQEVVEAP--ETPGEPPLSP 362
                  +S   P  V+  P   + G PP+ P
Sbjct: 575 PPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLP 606



 Score = 28.5 bits (62), Expect = 9.9
 Identities = 22/94 (23%), Positives = 33/94 (35%), Gaps = 3/94 (3%)

Query: 235 PAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGP-VEPASSQPE 293
           P     P    + S  +   ++ Q+      GP  P ++P    S    P V P S  P 
Sbjct: 103 PPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGP--PGLVPMELESPPESPPVPPGSYMPP 160

Query: 294 EAAPTPVPRLSESANPPAQRPDPAHPGGPKPQKT 327
             +  P P+   S  PP        P  P P ++
Sbjct: 161 SQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQS 194


>gi|94421473 paternally expressed 10 isoform RF1 [Homo sapiens]
          Length = 325

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 28/83 (33%), Positives = 42/83 (50%)

Query: 100 PGSDPGTFDGSPWLLDRFLAQLGDYMSFHFEHYQDNISRVCEILRRLTGRAQAWAAPYLD 159
           P   P  FDG+P +L  F+AQ   +M      +  +  RVC +   +TGRA  WA+  L+
Sbjct: 79  PEDLPEKFDGNPDMLAPFMAQCQIFMEKSTRDFSVDRVRVCFVTSMMTGRAARWASAKLE 138

Query: 160 GDLPLPDDYELFCQDLKEVVQDP 182
               L  +Y  F  ++K V +DP
Sbjct: 139 RSHYLMHNYPAFMMEMKHVFEDP 161


>gi|94421475 paternally expressed 10 isoform RF1/2 [Homo sapiens]
          Length = 708

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 28/83 (33%), Positives = 42/83 (50%)

Query: 100 PGSDPGTFDGSPWLLDRFLAQLGDYMSFHFEHYQDNISRVCEILRRLTGRAQAWAAPYLD 159
           P   P  FDG+P +L  F+AQ   +M      +  +  RVC +   +TGRA  WA+  L+
Sbjct: 79  PEDLPEKFDGNPDMLAPFMAQCQIFMEKSTRDFSVDRVRVCFVTSMMTGRAARWASAKLE 138

Query: 160 GDLPLPDDYELFCQDLKEVVQDP 182
               L  +Y  F  ++K V +DP
Sbjct: 139 RSHYLMHNYPAFMMEMKHVFEDP 161


>gi|118200333 family with sequence similarity 127, member B isoform
           1 [Homo sapiens]
          Length = 113

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 26/75 (34%), Positives = 38/75 (50%)

Query: 104 PGTFDGSPWLLDRFLAQLGDYMSFHFEHYQDNISRVCEILRRLTGRAQAWAAPYLDGDLP 163
           P TFDG    L  F+ Q   YM      + ++  +V  ++ RLTG A  W  PY+  + P
Sbjct: 30  PETFDGDTDRLPEFIVQTSSYMFVDENTFSNDALKVTFLITRLTGPALQWVIPYIRKESP 89

Query: 164 LPDDYELFCQDLKEV 178
           L +DY  F  ++K V
Sbjct: 90  LLNDYRGFLAEMKRV 104


>gi|118200337 family with sequence similarity 127, member C [Homo
           sapiens]
          Length = 113

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 26/75 (34%), Positives = 37/75 (49%)

Query: 104 PGTFDGSPWLLDRFLAQLGDYMSFHFEHYQDNISRVCEILRRLTGRAQAWAAPYLDGDLP 163
           P TFDG    L  F+ Q   YM      + ++  +V  ++ RLTG A  W  PY+  + P
Sbjct: 30  PETFDGDTDRLPEFIVQTSSYMFVDENTFSNDALKVTFLITRLTGPALQWVIPYIKKESP 89

Query: 164 LPDDYELFCQDLKEV 178
           L  DY  F  ++K V
Sbjct: 90  LLSDYRGFLAEMKRV 104


>gi|239757911 PREDICTED: similar to Family with sequence similarity
           127, member B [Homo sapiens]
          Length = 113

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 26/75 (34%), Positives = 38/75 (50%)

Query: 104 PGTFDGSPWLLDRFLAQLGDYMSFHFEHYQDNISRVCEILRRLTGRAQAWAAPYLDGDLP 163
           P TFDG    L  F+ Q   YM      + ++  +V  ++ RLTG A  W  PY+  + P
Sbjct: 30  PETFDGDTDRLPEFIVQTCSYMFVDENTFSNDALKVTFLITRLTGPALQWVIPYIRKESP 89

Query: 164 LPDDYELFCQDLKEV 178
           L +DY  F  ++K V
Sbjct: 90  LLNDYRGFLAEMKRV 104


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 47/154 (30%), Positives = 64/154 (41%), Gaps = 27/154 (17%)

Query: 230 APRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPG------PKEP----PVLPSSTCS 279
           AP +  +A  TP      +    A    +    +TP       PKEP    P  P+ T +
Sbjct: 404 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 463

Query: 280 SKPGPV---EPASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGP-KPQKTEEEVLETE 335
            KP P    EPA + P+E APT   +L+ +       P+   P  P KP  T  E L   
Sbjct: 464 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTT------PEKLAPTTPEKPAPTTPEELAPT 517

Query: 336 GDQEVSLGTPQE------VVEAPETPGEP-PLSP 362
             +E +  TP+E         AP TP EP P +P
Sbjct: 518 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 551



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 43/146 (29%), Positives = 61/146 (41%), Gaps = 17/146 (11%)

Query: 228 GTAPRS----LPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKE--PPVL--PSSTCS 279
           GTAP +     P     PA +     + + L E   T    P PKE  P     P+ST S
Sbjct: 622 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 681

Query: 280 SKPGPVEP---ASSQPEEAAPT----PVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVL 332
            KP P  P   A + P+E APT    P P   E+  PP    + + P   K   T  +  
Sbjct: 682 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET--PPPTTSEVSTPTTTKEPTTIHKSP 739

Query: 333 ETEGDQEVSLGTPQEVVEAPETPGEP 358
           +    +  +  TP+ +  +P+ PG P
Sbjct: 740 DESTPELSAEPTPKALENSPKEPGVP 765



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 43/129 (33%), Positives = 55/129 (42%), Gaps = 31/129 (24%)

Query: 261 KESTPGPKEP----PVLPSSTCSSKPGPV---EPASSQPEEAAPT------------PVP 301
           KE  P  KEP    P  P+ T   KP P    EPA + P+E APT            P P
Sbjct: 331 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 390

Query: 302 RLSESA-------NPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPET 354
             ++SA        P   +  P  P  P P  T+E    T   +E +  TP++   AP T
Sbjct: 391 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT--PKEPAPTTPKK--PAPTT 446

Query: 355 PGEP-PLSP 362
           P EP P +P
Sbjct: 447 PKEPAPTTP 455



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 43/139 (30%), Positives = 56/139 (40%), Gaps = 18/139 (12%)

Query: 229 TAPRSLPAAMATPAVSGSNSVSRSALFEQQLT--KESTPG-PKEPPVL---PSSTCSSKP 282
           T  +S P     PA +     + +   E   T  KE TP  PKEP      P+ T   +P
Sbjct: 289 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 348

Query: 283 GPV---EPASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQE 339
            P    +PA + P+E APT  P+  E A    + P P  P  P P  T+     T+    
Sbjct: 349 APTAPKKPAPTTPKEPAPT-TPK--EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP-- 403

Query: 340 VSLGTPQEVVEAPETPGEP 358
                P     AP TP EP
Sbjct: 404 ----APTTTKSAPTTPKEP 418



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 41/146 (28%), Positives = 59/146 (40%), Gaps = 21/146 (14%)

Query: 230 APRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPAS 289
           AP +  +A  TP      +    A       KE  P   + P  P++T S+   P EPA 
Sbjct: 248 APTTTKSAPTTPKEPAPTTTKEPA---PTTPKEPAPTTTKEPA-PTTTKSAPTTPKEPAP 303

Query: 290 SQPEEAAPT------------PVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGD 337
           + P++ APT            P P   +   P  + P P  P  P P   ++    T   
Sbjct: 304 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT--P 361

Query: 338 QEVSLGTPQEVVEAPETPGEP-PLSP 362
           +E +  TP+E   AP T  EP P +P
Sbjct: 362 KEPAPTTPKE--PAPTTTKEPSPTTP 385



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 36/107 (33%), Positives = 48/107 (44%), Gaps = 16/107 (14%)

Query: 267 PKEP----PVLPSSTCSSKPGP--VEPASSQPEEAAPTPVPRLSESANPPA----QRPDP 316
           PKEP    P  P+ST   +P P  ++ A + P+E APT       +   PA    + P P
Sbjct: 213 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 272

Query: 317 AHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEP-PLSP 362
             P  P P  T+E    T         TP+E   AP TP +P P +P
Sbjct: 273 TTPKEPAPTTTKEPAPTTTKSAPT---TPKE--PAPTTPKKPAPTTP 314



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 37/117 (31%), Positives = 51/117 (43%), Gaps = 23/117 (19%)

Query: 261 KESTP-GPKEP----PVLPSSTCSSKPGPV---EPASSQPEEAAPT-----------PVP 301
           KE  P  PK+P    P  P+ T   +P P    EP+ + P+E APT           P P
Sbjct: 346 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 405

Query: 302 RLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEP 358
             ++SA    + P P     P P   +E    T   ++ +  TP+E   AP TP EP
Sbjct: 406 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT--PKKPAPTTPKE--PAPTTPKEP 458



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 44/141 (31%), Positives = 60/141 (42%), Gaps = 18/141 (12%)

Query: 228 GTAPRSLPA-AMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVE 286
           GTAP +L   A  TP       ++ +   E   T    P P  P     +T      P E
Sbjct: 577 GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT------PKE 630

Query: 287 PASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGPKPQK----TEEEVLETEGDQEVSL 342
           PA + P+E APT  P+   +A    + P P  P  P P++    T +    T  D+    
Sbjct: 631 PAPTTPKEPAPT-TPK--GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 687

Query: 343 GTPQEVVEAPETPGEP-PLSP 362
            TP+E   AP TP EP P +P
Sbjct: 688 -TPKET--APTTPKEPAPTTP 705



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 32/109 (29%), Positives = 44/109 (40%), Gaps = 10/109 (9%)

Query: 264 TPGPKEPPVLPSSTCSSKPGPV---EPASSQPEEAAPTPV---PRLSESANPPAQRPDPA 317
           TP  +     P+ T   +P P    EPAS+ P+E  PT +   P   +   P   +  P 
Sbjct: 198 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT 257

Query: 318 HPGGPKPQKTEEEVLETEGDQEVSL---GTPQEVVEAPETPGEP-PLSP 362
            P  P P  T+E    T  +   +      P     AP TP EP P +P
Sbjct: 258 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 306



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 39/141 (27%), Positives = 57/141 (40%), Gaps = 11/141 (7%)

Query: 229 TAPRS-LPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEP 287
           TAP+   P     PA +     + +   E   T    P P      P++T    P   + 
Sbjct: 351 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 410

Query: 288 ASSQPEEAAPT----PVPRL-SESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSL 342
           A + P+E +PT    P P    E A    ++P P  P  P P   +E    T   ++ + 
Sbjct: 411 APTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT--TKKPAP 468

Query: 343 GTPQEVVEAPETPGE-PPLSP 362
            TP+E   AP TP E  P +P
Sbjct: 469 TTPKE--PAPTTPKETAPTTP 487



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 36/120 (30%), Positives = 50/120 (41%), Gaps = 21/120 (17%)

Query: 261 KESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPT----PVPRLSESANPPA----- 311
           +E TP   E P   +   ++   P EPA + P+E APT    P P   +   P       
Sbjct: 520 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 579

Query: 312 ----QRPDPAHPGGPKPQK----TEEEVLETEGDQEVSLGTPQEVVEAPETPGEP-PLSP 362
               + P P  P  P P++    T +E   T  D+     TP+    AP TP EP P +P
Sbjct: 580 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT-TPKGT--APTTPKEPAPTTP 636



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 33/105 (31%), Positives = 41/105 (39%), Gaps = 17/105 (16%)

Query: 260 TKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAP-TPVPRLSESANPPA----QRP 314
           T    P P  P  L  +T      P EP  + PEE AP TP      +   PA    + P
Sbjct: 501 TTPEKPAPTTPEELAPTT------PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 554

Query: 315 DPAHPGGPKPQKTEEEVLET-EGDQEVSLGTPQEVVEAPETPGEP 358
            P  P  P P   +E    T +G    +L  P     AP TP +P
Sbjct: 555 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEP-----APTTPKKP 594



 Score = 36.2 bits (82), Expect = 0.047
 Identities = 44/142 (30%), Positives = 56/142 (39%), Gaps = 42/142 (29%)

Query: 261 KESTPG-PKEP----PVLPSSTC--SSKPGPVEPASSQ-------PEEAAPT-------- 298
           KE TP  PKEP    P  P+ T   S+   P EPA +        P+E APT        
Sbjct: 214 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 273

Query: 299 ------------PVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQ 346
                       P P  ++SA    + P P  P  P P   +E    T   +E +  TP+
Sbjct: 274 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT--PKEPTPTTPK 331

Query: 347 EVV-----EAPETPGEP-PLSP 362
           E        AP TP EP P +P
Sbjct: 332 EPAPTTKEPAPTTPKEPAPTAP 353



 Score = 36.2 bits (82), Expect = 0.047
 Identities = 49/199 (24%), Positives = 62/199 (31%), Gaps = 37/199 (18%)

Query: 193 TCPLPLASSQLPVAPQLPVVRQYLARFLEGLALDMGTAPRSLPA-AMATPAVSGSNSVSR 251
           TC  P  ++    AP  P                 GTAP +L   A  TP       ++ 
Sbjct: 611 TCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 670

Query: 252 SALFEQQLTKESTPGPKEP-------PVLPSSTCSSKPGPVEPASSQP---EEAAPTPV- 300
           +       T    P P  P       P  P+ T   KP P  P +  P   E + PT   
Sbjct: 671 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 730

Query: 301 -------------PRLSESANPPAQRPDPAHPGGP--------KPQ-KTEEEVLETEGDQ 338
                        P LS    P A    P  PG P        KP+  T  +   TE D 
Sbjct: 731 EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDL 790

Query: 339 EVSLGTPQEVVEAPETPGE 357
                TP+    AP+   E
Sbjct: 791 RT---TPETTTAAPKMTKE 806



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 34/121 (28%), Positives = 46/121 (38%), Gaps = 9/121 (7%)

Query: 237 AMATPAVSGSNSVSRSALFEQQLTKESTPG-PKEP-PVLPSSTCSSKPGPVEPASSQPEE 294
           A  TP  +  N+    A       KE  P  PKEP P  P  T  + P    P + +  E
Sbjct: 531 APTTPKAAAPNTPKEPA---PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK--E 585

Query: 295 AAPTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPET 354
            APT   + +     P    +P      KP  T  +       +E +  TP+E   AP T
Sbjct: 586 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE--PAPTT 643

Query: 355 P 355
           P
Sbjct: 644 P 644


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 47/154 (30%), Positives = 64/154 (41%), Gaps = 27/154 (17%)

Query: 230 APRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPG------PKEP----PVLPSSTCS 279
           AP +  +A  TP      +    A    +    +TP       PKEP    P  P+ T +
Sbjct: 445 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 504

Query: 280 SKPGPV---EPASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGP-KPQKTEEEVLETE 335
            KP P    EPA + P+E APT   +L+ +       P+   P  P KP  T  E L   
Sbjct: 505 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTT------PEKLAPTTPEKPAPTTPEELAPT 558

Query: 336 GDQEVSLGTPQE------VVEAPETPGEP-PLSP 362
             +E +  TP+E         AP TP EP P +P
Sbjct: 559 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 592



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 43/146 (29%), Positives = 61/146 (41%), Gaps = 17/146 (11%)

Query: 228 GTAPRS----LPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKE--PPVL--PSSTCS 279
           GTAP +     P     PA +     + + L E   T    P PKE  P     P+ST S
Sbjct: 663 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 722

Query: 280 SKPGPVEP---ASSQPEEAAPT----PVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVL 332
            KP P  P   A + P+E APT    P P   E+  PP    + + P   K   T  +  
Sbjct: 723 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET--PPPTTSEVSTPTTTKEPTTIHKSP 780

Query: 333 ETEGDQEVSLGTPQEVVEAPETPGEP 358
           +    +  +  TP+ +  +P+ PG P
Sbjct: 781 DESTPELSAEPTPKALENSPKEPGVP 806



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 43/129 (33%), Positives = 55/129 (42%), Gaps = 31/129 (24%)

Query: 261 KESTPGPKEP----PVLPSSTCSSKPGPV---EPASSQPEEAAPT------------PVP 301
           KE  P  KEP    P  P+ T   KP P    EPA + P+E APT            P P
Sbjct: 372 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 431

Query: 302 RLSESA-------NPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPET 354
             ++SA        P   +  P  P  P P  T+E    T   +E +  TP++   AP T
Sbjct: 432 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT--PKEPAPTTPKK--PAPTT 487

Query: 355 PGEP-PLSP 362
           P EP P +P
Sbjct: 488 PKEPAPTTP 496



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 43/139 (30%), Positives = 56/139 (40%), Gaps = 18/139 (12%)

Query: 229 TAPRSLPAAMATPAVSGSNSVSRSALFEQQLT--KESTPG-PKEPPVL---PSSTCSSKP 282
           T  +S P     PA +     + +   E   T  KE TP  PKEP      P+ T   +P
Sbjct: 330 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 389

Query: 283 GPV---EPASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQE 339
            P    +PA + P+E APT  P+  E A    + P P  P  P P  T+     T+    
Sbjct: 390 APTAPKKPAPTTPKEPAPT-TPK--EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP-- 444

Query: 340 VSLGTPQEVVEAPETPGEP 358
                P     AP TP EP
Sbjct: 445 ----APTTTKSAPTTPKEP 459



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 41/146 (28%), Positives = 59/146 (40%), Gaps = 21/146 (14%)

Query: 230 APRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPAS 289
           AP +  +A  TP      +    A       KE  P   + P  P++T S+   P EPA 
Sbjct: 289 APTTTKSAPTTPKEPAPTTTKEPA---PTTPKEPAPTTTKEPA-PTTTKSAPTTPKEPAP 344

Query: 290 SQPEEAAPT------------PVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGD 337
           + P++ APT            P P   +   P  + P P  P  P P   ++    T   
Sbjct: 345 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT--P 402

Query: 338 QEVSLGTPQEVVEAPETPGEP-PLSP 362
           +E +  TP+E   AP T  EP P +P
Sbjct: 403 KEPAPTTPKE--PAPTTTKEPSPTTP 426



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 36/107 (33%), Positives = 48/107 (44%), Gaps = 16/107 (14%)

Query: 267 PKEP----PVLPSSTCSSKPGP--VEPASSQPEEAAPTPVPRLSESANPPA----QRPDP 316
           PKEP    P  P+ST   +P P  ++ A + P+E APT       +   PA    + P P
Sbjct: 254 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 313

Query: 317 AHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEP-PLSP 362
             P  P P  T+E    T         TP+E   AP TP +P P +P
Sbjct: 314 TTPKEPAPTTTKEPAPTTTKSAPT---TPKE--PAPTTPKKPAPTTP 355



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 37/117 (31%), Positives = 51/117 (43%), Gaps = 23/117 (19%)

Query: 261 KESTP-GPKEP----PVLPSSTCSSKPGPV---EPASSQPEEAAPT-----------PVP 301
           KE  P  PK+P    P  P+ T   +P P    EP+ + P+E APT           P P
Sbjct: 387 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 446

Query: 302 RLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEP 358
             ++SA    + P P     P P   +E    T   ++ +  TP+E   AP TP EP
Sbjct: 447 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT--PKKPAPTTPKE--PAPTTPKEP 499



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 44/141 (31%), Positives = 60/141 (42%), Gaps = 18/141 (12%)

Query: 228 GTAPRSLPA-AMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVE 286
           GTAP +L   A  TP       ++ +   E   T    P P  P     +T      P E
Sbjct: 618 GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT------PKE 671

Query: 287 PASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGPKPQK----TEEEVLETEGDQEVSL 342
           PA + P+E APT  P+   +A    + P P  P  P P++    T +    T  D+    
Sbjct: 672 PAPTTPKEPAPT-TPK--GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 728

Query: 343 GTPQEVVEAPETPGEP-PLSP 362
            TP+E   AP TP EP P +P
Sbjct: 729 -TPKET--APTTPKEPAPTTP 746



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 32/109 (29%), Positives = 44/109 (40%), Gaps = 10/109 (9%)

Query: 264 TPGPKEPPVLPSSTCSSKPGPV---EPASSQPEEAAPTPV---PRLSESANPPAQRPDPA 317
           TP  +     P+ T   +P P    EPAS+ P+E  PT +   P   +   P   +  P 
Sbjct: 239 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT 298

Query: 318 HPGGPKPQKTEEEVLETEGDQEVSL---GTPQEVVEAPETPGEP-PLSP 362
            P  P P  T+E    T  +   +      P     AP TP EP P +P
Sbjct: 299 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 347



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 39/141 (27%), Positives = 57/141 (40%), Gaps = 11/141 (7%)

Query: 229 TAPRS-LPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEP 287
           TAP+   P     PA +     + +   E   T    P P      P++T    P   + 
Sbjct: 392 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 451

Query: 288 ASSQPEEAAPT----PVPRL-SESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSL 342
           A + P+E +PT    P P    E A    ++P P  P  P P   +E    T   ++ + 
Sbjct: 452 APTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT--TKKPAP 509

Query: 343 GTPQEVVEAPETPGE-PPLSP 362
            TP+E   AP TP E  P +P
Sbjct: 510 TTPKE--PAPTTPKETAPTTP 528



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 36/120 (30%), Positives = 50/120 (41%), Gaps = 21/120 (17%)

Query: 261 KESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPT----PVPRLSESANPPA----- 311
           +E TP   E P   +   ++   P EPA + P+E APT    P P   +   P       
Sbjct: 561 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 620

Query: 312 ----QRPDPAHPGGPKPQK----TEEEVLETEGDQEVSLGTPQEVVEAPETPGEP-PLSP 362
               + P P  P  P P++    T +E   T  D+     TP+    AP TP EP P +P
Sbjct: 621 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT-TPKGT--APTTPKEPAPTTP 677



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 33/105 (31%), Positives = 41/105 (39%), Gaps = 17/105 (16%)

Query: 260 TKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAP-TPVPRLSESANPPA----QRP 314
           T    P P  P  L  +T      P EP  + PEE AP TP      +   PA    + P
Sbjct: 542 TTPEKPAPTTPEELAPTT------PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 595

Query: 315 DPAHPGGPKPQKTEEEVLET-EGDQEVSLGTPQEVVEAPETPGEP 358
            P  P  P P   +E    T +G    +L  P     AP TP +P
Sbjct: 596 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEP-----APTTPKKP 635



 Score = 36.2 bits (82), Expect = 0.047
 Identities = 44/142 (30%), Positives = 56/142 (39%), Gaps = 42/142 (29%)

Query: 261 KESTPG-PKEP----PVLPSSTC--SSKPGPVEPASSQ-------PEEAAPT-------- 298
           KE TP  PKEP    P  P+ T   S+   P EPA +        P+E APT        
Sbjct: 255 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 314

Query: 299 ------------PVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQ 346
                       P P  ++SA    + P P  P  P P   +E    T   +E +  TP+
Sbjct: 315 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT--PKEPTPTTPK 372

Query: 347 EVV-----EAPETPGEP-PLSP 362
           E        AP TP EP P +P
Sbjct: 373 EPAPTTKEPAPTTPKEPAPTAP 394



 Score = 36.2 bits (82), Expect = 0.047
 Identities = 49/199 (24%), Positives = 62/199 (31%), Gaps = 37/199 (18%)

Query: 193 TCPLPLASSQLPVAPQLPVVRQYLARFLEGLALDMGTAPRSLPA-AMATPAVSGSNSVSR 251
           TC  P  ++    AP  P                 GTAP +L   A  TP       ++ 
Sbjct: 652 TCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 711

Query: 252 SALFEQQLTKESTPGPKEP-------PVLPSSTCSSKPGPVEPASSQP---EEAAPTPV- 300
           +       T    P P  P       P  P+ T   KP P  P +  P   E + PT   
Sbjct: 712 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 771

Query: 301 -------------PRLSESANPPAQRPDPAHPGGP--------KPQ-KTEEEVLETEGDQ 338
                        P LS    P A    P  PG P        KP+  T  +   TE D 
Sbjct: 772 EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDL 831

Query: 339 EVSLGTPQEVVEAPETPGE 357
                TP+    AP+   E
Sbjct: 832 RT---TPETTTAAPKMTKE 847



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 34/121 (28%), Positives = 46/121 (38%), Gaps = 9/121 (7%)

Query: 237 AMATPAVSGSNSVSRSALFEQQLTKESTPG-PKEP-PVLPSSTCSSKPGPVEPASSQPEE 294
           A  TP  +  N+    A       KE  P  PKEP P  P  T  + P    P + +  E
Sbjct: 572 APTTPKAAAPNTPKEPA---PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK--E 626

Query: 295 AAPTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPET 354
            APT   + +     P    +P      KP  T  +       +E +  TP+E   AP T
Sbjct: 627 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE--PAPTT 684

Query: 355 P 355
           P
Sbjct: 685 P 685


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 47/154 (30%), Positives = 64/154 (41%), Gaps = 27/154 (17%)

Query: 230 APRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPG------PKEP----PVLPSSTCS 279
           AP +  +A  TP      +    A    +    +TP       PKEP    P  P+ T +
Sbjct: 497 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 556

Query: 280 SKPGPV---EPASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGP-KPQKTEEEVLETE 335
            KP P    EPA + P+E APT   +L+ +       P+   P  P KP  T  E L   
Sbjct: 557 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTT------PEKLAPTTPEKPAPTTPEELAPT 610

Query: 336 GDQEVSLGTPQE------VVEAPETPGEP-PLSP 362
             +E +  TP+E         AP TP EP P +P
Sbjct: 611 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 644



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 43/146 (29%), Positives = 61/146 (41%), Gaps = 17/146 (11%)

Query: 228 GTAPRS----LPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKE--PPVL--PSSTCS 279
           GTAP +     P     PA +     + + L E   T    P PKE  P     P+ST S
Sbjct: 715 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 774

Query: 280 SKPGPVEP---ASSQPEEAAPT----PVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVL 332
            KP P  P   A + P+E APT    P P   E+  PP    + + P   K   T  +  
Sbjct: 775 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET--PPPTTSEVSTPTTTKEPTTIHKSP 832

Query: 333 ETEGDQEVSLGTPQEVVEAPETPGEP 358
           +    +  +  TP+ +  +P+ PG P
Sbjct: 833 DESTPELSAEPTPKALENSPKEPGVP 858



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 43/129 (33%), Positives = 55/129 (42%), Gaps = 31/129 (24%)

Query: 261 KESTPGPKEP----PVLPSSTCSSKPGPV---EPASSQPEEAAPT------------PVP 301
           KE  P  KEP    P  P+ T   KP P    EPA + P+E APT            P P
Sbjct: 424 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 483

Query: 302 RLSESA-------NPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPET 354
             ++SA        P   +  P  P  P P  T+E    T   +E +  TP++   AP T
Sbjct: 484 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT--PKEPAPTTPKK--PAPTT 539

Query: 355 PGEP-PLSP 362
           P EP P +P
Sbjct: 540 PKEPAPTTP 548



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 43/139 (30%), Positives = 56/139 (40%), Gaps = 18/139 (12%)

Query: 229 TAPRSLPAAMATPAVSGSNSVSRSALFEQQLT--KESTPG-PKEPPVL---PSSTCSSKP 282
           T  +S P     PA +     + +   E   T  KE TP  PKEP      P+ T   +P
Sbjct: 382 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 441

Query: 283 GPV---EPASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQE 339
            P    +PA + P+E APT  P+  E A    + P P  P  P P  T+     T+    
Sbjct: 442 APTAPKKPAPTTPKEPAPT-TPK--EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP-- 496

Query: 340 VSLGTPQEVVEAPETPGEP 358
                P     AP TP EP
Sbjct: 497 ----APTTTKSAPTTPKEP 511



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 41/146 (28%), Positives = 59/146 (40%), Gaps = 21/146 (14%)

Query: 230 APRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPAS 289
           AP +  +A  TP      +    A       KE  P   + P  P++T S+   P EPA 
Sbjct: 341 APTTTKSAPTTPKEPAPTTTKEPA---PTTPKEPAPTTTKEPA-PTTTKSAPTTPKEPAP 396

Query: 290 SQPEEAAPT------------PVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGD 337
           + P++ APT            P P   +   P  + P P  P  P P   ++    T   
Sbjct: 397 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT--P 454

Query: 338 QEVSLGTPQEVVEAPETPGEP-PLSP 362
           +E +  TP+E   AP T  EP P +P
Sbjct: 455 KEPAPTTPKE--PAPTTTKEPSPTTP 478



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 36/107 (33%), Positives = 48/107 (44%), Gaps = 16/107 (14%)

Query: 267 PKEP----PVLPSSTCSSKPGP--VEPASSQPEEAAPTPVPRLSESANPPA----QRPDP 316
           PKEP    P  P+ST   +P P  ++ A + P+E APT       +   PA    + P P
Sbjct: 306 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 365

Query: 317 AHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEP-PLSP 362
             P  P P  T+E    T         TP+E   AP TP +P P +P
Sbjct: 366 TTPKEPAPTTTKEPAPTTTKSAPT---TPKE--PAPTTPKKPAPTTP 407



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 37/117 (31%), Positives = 51/117 (43%), Gaps = 23/117 (19%)

Query: 261 KESTP-GPKEP----PVLPSSTCSSKPGPV---EPASSQPEEAAPT-----------PVP 301
           KE  P  PK+P    P  P+ T   +P P    EP+ + P+E APT           P P
Sbjct: 439 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 498

Query: 302 RLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEP 358
             ++SA    + P P     P P   +E    T   ++ +  TP+E   AP TP EP
Sbjct: 499 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT--PKKPAPTTPKE--PAPTTPKEP 551



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 44/141 (31%), Positives = 60/141 (42%), Gaps = 18/141 (12%)

Query: 228 GTAPRSLPA-AMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVE 286
           GTAP +L   A  TP       ++ +   E   T    P P  P     +T      P E
Sbjct: 670 GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT------PKE 723

Query: 287 PASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGPKPQK----TEEEVLETEGDQEVSL 342
           PA + P+E APT  P+   +A    + P P  P  P P++    T +    T  D+    
Sbjct: 724 PAPTTPKEPAPT-TPK--GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 780

Query: 343 GTPQEVVEAPETPGEP-PLSP 362
            TP+E   AP TP EP P +P
Sbjct: 781 -TPKET--APTTPKEPAPTTP 798



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 32/109 (29%), Positives = 44/109 (40%), Gaps = 10/109 (9%)

Query: 264 TPGPKEPPVLPSSTCSSKPGPV---EPASSQPEEAAPTPV---PRLSESANPPAQRPDPA 317
           TP  +     P+ T   +P P    EPAS+ P+E  PT +   P   +   P   +  P 
Sbjct: 291 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT 350

Query: 318 HPGGPKPQKTEEEVLETEGDQEVSL---GTPQEVVEAPETPGEP-PLSP 362
            P  P P  T+E    T  +   +      P     AP TP EP P +P
Sbjct: 351 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 399



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 39/141 (27%), Positives = 57/141 (40%), Gaps = 11/141 (7%)

Query: 229 TAPRS-LPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEP 287
           TAP+   P     PA +     + +   E   T    P P      P++T    P   + 
Sbjct: 444 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 503

Query: 288 ASSQPEEAAPT----PVPRL-SESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSL 342
           A + P+E +PT    P P    E A    ++P P  P  P P   +E    T   ++ + 
Sbjct: 504 APTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT--TKKPAP 561

Query: 343 GTPQEVVEAPETPGE-PPLSP 362
            TP+E   AP TP E  P +P
Sbjct: 562 TTPKE--PAPTTPKETAPTTP 580



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 36/120 (30%), Positives = 50/120 (41%), Gaps = 21/120 (17%)

Query: 261 KESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPT----PVPRLSESANPPA----- 311
           +E TP   E P   +   ++   P EPA + P+E APT    P P   +   P       
Sbjct: 613 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 672

Query: 312 ----QRPDPAHPGGPKPQK----TEEEVLETEGDQEVSLGTPQEVVEAPETPGEP-PLSP 362
               + P P  P  P P++    T +E   T  D+     TP+    AP TP EP P +P
Sbjct: 673 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT-TPKGT--APTTPKEPAPTTP 729



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 33/105 (31%), Positives = 41/105 (39%), Gaps = 17/105 (16%)

Query: 260 TKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAP-TPVPRLSESANPPA----QRP 314
           T    P P  P  L  +T      P EP  + PEE AP TP      +   PA    + P
Sbjct: 594 TTPEKPAPTTPEELAPTT------PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 647

Query: 315 DPAHPGGPKPQKTEEEVLET-EGDQEVSLGTPQEVVEAPETPGEP 358
            P  P  P P   +E    T +G    +L  P     AP TP +P
Sbjct: 648 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEP-----APTTPKKP 687



 Score = 36.2 bits (82), Expect = 0.047
 Identities = 44/142 (30%), Positives = 56/142 (39%), Gaps = 42/142 (29%)

Query: 261 KESTPG-PKEP----PVLPSSTC--SSKPGPVEPASSQ-------PEEAAPT-------- 298
           KE TP  PKEP    P  P+ T   S+   P EPA +        P+E APT        
Sbjct: 307 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 366

Query: 299 ------------PVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQ 346
                       P P  ++SA    + P P  P  P P   +E    T   +E +  TP+
Sbjct: 367 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT--PKEPTPTTPK 424

Query: 347 EVV-----EAPETPGEP-PLSP 362
           E        AP TP EP P +P
Sbjct: 425 EPAPTTKEPAPTTPKEPAPTAP 446



 Score = 36.2 bits (82), Expect = 0.047
 Identities = 49/199 (24%), Positives = 62/199 (31%), Gaps = 37/199 (18%)

Query: 193 TCPLPLASSQLPVAPQLPVVRQYLARFLEGLALDMGTAPRSLPA-AMATPAVSGSNSVSR 251
           TC  P  ++    AP  P                 GTAP +L   A  TP       ++ 
Sbjct: 704 TCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 763

Query: 252 SALFEQQLTKESTPGPKEP-------PVLPSSTCSSKPGPVEPASSQP---EEAAPTPV- 300
           +       T    P P  P       P  P+ T   KP P  P +  P   E + PT   
Sbjct: 764 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 823

Query: 301 -------------PRLSESANPPAQRPDPAHPGGP--------KPQ-KTEEEVLETEGDQ 338
                        P LS    P A    P  PG P        KP+  T  +   TE D 
Sbjct: 824 EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDL 883

Query: 339 EVSLGTPQEVVEAPETPGE 357
                TP+    AP+   E
Sbjct: 884 RT---TPETTTAAPKMTKE 899



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 34/121 (28%), Positives = 46/121 (38%), Gaps = 9/121 (7%)

Query: 237 AMATPAVSGSNSVSRSALFEQQLTKESTPG-PKEP-PVLPSSTCSSKPGPVEPASSQPEE 294
           A  TP  +  N+    A       KE  P  PKEP P  P  T  + P    P + +  E
Sbjct: 624 APTTPKAAAPNTPKEPA---PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK--E 678

Query: 295 AAPTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPET 354
            APT   + +     P    +P      KP  T  +       +E +  TP+E   AP T
Sbjct: 679 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE--PAPTT 736

Query: 355 P 355
           P
Sbjct: 737 P 737


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 47/154 (30%), Positives = 64/154 (41%), Gaps = 27/154 (17%)

Query: 230 APRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPG------PKEP----PVLPSSTCS 279
           AP +  +A  TP      +    A    +    +TP       PKEP    P  P+ T +
Sbjct: 538 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 597

Query: 280 SKPGPV---EPASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGP-KPQKTEEEVLETE 335
            KP P    EPA + P+E APT   +L+ +       P+   P  P KP  T  E L   
Sbjct: 598 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTT------PEKLAPTTPEKPAPTTPEELAPT 651

Query: 336 GDQEVSLGTPQE------VVEAPETPGEP-PLSP 362
             +E +  TP+E         AP TP EP P +P
Sbjct: 652 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 685



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 43/146 (29%), Positives = 61/146 (41%), Gaps = 17/146 (11%)

Query: 228 GTAPRS----LPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKE--PPVL--PSSTCS 279
           GTAP +     P     PA +     + + L E   T    P PKE  P     P+ST S
Sbjct: 756 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 815

Query: 280 SKPGPVEP---ASSQPEEAAPT----PVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVL 332
            KP P  P   A + P+E APT    P P   E+  PP    + + P   K   T  +  
Sbjct: 816 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET--PPPTTSEVSTPTTTKEPTTIHKSP 873

Query: 333 ETEGDQEVSLGTPQEVVEAPETPGEP 358
           +    +  +  TP+ +  +P+ PG P
Sbjct: 874 DESTPELSAEPTPKALENSPKEPGVP 899



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 43/129 (33%), Positives = 55/129 (42%), Gaps = 31/129 (24%)

Query: 261 KESTPGPKEP----PVLPSSTCSSKPGPV---EPASSQPEEAAPT------------PVP 301
           KE  P  KEP    P  P+ T   KP P    EPA + P+E APT            P P
Sbjct: 465 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 524

Query: 302 RLSESA-------NPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPET 354
             ++SA        P   +  P  P  P P  T+E    T   +E +  TP++   AP T
Sbjct: 525 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT--PKEPAPTTPKK--PAPTT 580

Query: 355 PGEP-PLSP 362
           P EP P +P
Sbjct: 581 PKEPAPTTP 589



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 43/139 (30%), Positives = 56/139 (40%), Gaps = 18/139 (12%)

Query: 229 TAPRSLPAAMATPAVSGSNSVSRSALFEQQLT--KESTPG-PKEPPVL---PSSTCSSKP 282
           T  +S P     PA +     + +   E   T  KE TP  PKEP      P+ T   +P
Sbjct: 423 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 482

Query: 283 GPV---EPASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQE 339
            P    +PA + P+E APT  P+  E A    + P P  P  P P  T+     T+    
Sbjct: 483 APTAPKKPAPTTPKEPAPT-TPK--EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP-- 537

Query: 340 VSLGTPQEVVEAPETPGEP 358
                P     AP TP EP
Sbjct: 538 ----APTTTKSAPTTPKEP 552



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 41/146 (28%), Positives = 59/146 (40%), Gaps = 21/146 (14%)

Query: 230 APRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPAS 289
           AP +  +A  TP      +    A       KE  P   + P  P++T S+   P EPA 
Sbjct: 382 APTTTKSAPTTPKEPAPTTTKEPA---PTTPKEPAPTTTKEPA-PTTTKSAPTTPKEPAP 437

Query: 290 SQPEEAAPT------------PVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGD 337
           + P++ APT            P P   +   P  + P P  P  P P   ++    T   
Sbjct: 438 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT--P 495

Query: 338 QEVSLGTPQEVVEAPETPGEP-PLSP 362
           +E +  TP+E   AP T  EP P +P
Sbjct: 496 KEPAPTTPKE--PAPTTTKEPSPTTP 519



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 36/107 (33%), Positives = 48/107 (44%), Gaps = 16/107 (14%)

Query: 267 PKEP----PVLPSSTCSSKPGP--VEPASSQPEEAAPTPVPRLSESANPPA----QRPDP 316
           PKEP    P  P+ST   +P P  ++ A + P+E APT       +   PA    + P P
Sbjct: 347 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 406

Query: 317 AHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEP-PLSP 362
             P  P P  T+E    T         TP+E   AP TP +P P +P
Sbjct: 407 TTPKEPAPTTTKEPAPTTTKSAPT---TPKE--PAPTTPKKPAPTTP 448



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 37/117 (31%), Positives = 51/117 (43%), Gaps = 23/117 (19%)

Query: 261 KESTP-GPKEP----PVLPSSTCSSKPGPV---EPASSQPEEAAPT-----------PVP 301
           KE  P  PK+P    P  P+ T   +P P    EP+ + P+E APT           P P
Sbjct: 480 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 539

Query: 302 RLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEP 358
             ++SA    + P P     P P   +E    T   ++ +  TP+E   AP TP EP
Sbjct: 540 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT--PKKPAPTTPKE--PAPTTPKEP 592



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 44/141 (31%), Positives = 60/141 (42%), Gaps = 18/141 (12%)

Query: 228 GTAPRSLPA-AMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVE 286
           GTAP +L   A  TP       ++ +   E   T    P P  P     +T      P E
Sbjct: 711 GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT------PKE 764

Query: 287 PASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGPKPQK----TEEEVLETEGDQEVSL 342
           PA + P+E APT  P+   +A    + P P  P  P P++    T +    T  D+    
Sbjct: 765 PAPTTPKEPAPT-TPK--GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 821

Query: 343 GTPQEVVEAPETPGEP-PLSP 362
            TP+E   AP TP EP P +P
Sbjct: 822 -TPKET--APTTPKEPAPTTP 839



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 32/109 (29%), Positives = 44/109 (40%), Gaps = 10/109 (9%)

Query: 264 TPGPKEPPVLPSSTCSSKPGPV---EPASSQPEEAAPTPV---PRLSESANPPAQRPDPA 317
           TP  +     P+ T   +P P    EPAS+ P+E  PT +   P   +   P   +  P 
Sbjct: 332 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT 391

Query: 318 HPGGPKPQKTEEEVLETEGDQEVSL---GTPQEVVEAPETPGEP-PLSP 362
            P  P P  T+E    T  +   +      P     AP TP EP P +P
Sbjct: 392 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 440



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 39/141 (27%), Positives = 57/141 (40%), Gaps = 11/141 (7%)

Query: 229 TAPRS-LPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEP 287
           TAP+   P     PA +     + +   E   T    P P      P++T    P   + 
Sbjct: 485 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 544

Query: 288 ASSQPEEAAPT----PVPRL-SESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSL 342
           A + P+E +PT    P P    E A    ++P P  P  P P   +E    T   ++ + 
Sbjct: 545 APTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT--TKKPAP 602

Query: 343 GTPQEVVEAPETPGE-PPLSP 362
            TP+E   AP TP E  P +P
Sbjct: 603 TTPKE--PAPTTPKETAPTTP 621



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 36/120 (30%), Positives = 50/120 (41%), Gaps = 21/120 (17%)

Query: 261 KESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPT----PVPRLSESANPPA----- 311
           +E TP   E P   +   ++   P EPA + P+E APT    P P   +   P       
Sbjct: 654 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 713

Query: 312 ----QRPDPAHPGGPKPQK----TEEEVLETEGDQEVSLGTPQEVVEAPETPGEP-PLSP 362
               + P P  P  P P++    T +E   T  D+     TP+    AP TP EP P +P
Sbjct: 714 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT-TPKGT--APTTPKEPAPTTP 770



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 33/105 (31%), Positives = 41/105 (39%), Gaps = 17/105 (16%)

Query: 260 TKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAP-TPVPRLSESANPPA----QRP 314
           T    P P  P  L  +T      P EP  + PEE AP TP      +   PA    + P
Sbjct: 635 TTPEKPAPTTPEELAPTT------PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 688

Query: 315 DPAHPGGPKPQKTEEEVLET-EGDQEVSLGTPQEVVEAPETPGEP 358
            P  P  P P   +E    T +G    +L  P     AP TP +P
Sbjct: 689 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEP-----APTTPKKP 728



 Score = 36.2 bits (82), Expect = 0.047
 Identities = 44/142 (30%), Positives = 56/142 (39%), Gaps = 42/142 (29%)

Query: 261 KESTPG-PKEP----PVLPSSTC--SSKPGPVEPASSQ-------PEEAAPT-------- 298
           KE TP  PKEP    P  P+ T   S+   P EPA +        P+E APT        
Sbjct: 348 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 407

Query: 299 ------------PVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQ 346
                       P P  ++SA    + P P  P  P P   +E    T   +E +  TP+
Sbjct: 408 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT--PKEPTPTTPK 465

Query: 347 EVV-----EAPETPGEP-PLSP 362
           E        AP TP EP P +P
Sbjct: 466 EPAPTTKEPAPTTPKEPAPTAP 487



 Score = 36.2 bits (82), Expect = 0.047
 Identities = 49/199 (24%), Positives = 62/199 (31%), Gaps = 37/199 (18%)

Query: 193 TCPLPLASSQLPVAPQLPVVRQYLARFLEGLALDMGTAPRSLPA-AMATPAVSGSNSVSR 251
           TC  P  ++    AP  P                 GTAP +L   A  TP       ++ 
Sbjct: 745 TCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 804

Query: 252 SALFEQQLTKESTPGPKEP-------PVLPSSTCSSKPGPVEPASSQP---EEAAPTPV- 300
           +       T    P P  P       P  P+ T   KP P  P +  P   E + PT   
Sbjct: 805 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 864

Query: 301 -------------PRLSESANPPAQRPDPAHPGGP--------KPQ-KTEEEVLETEGDQ 338
                        P LS    P A    P  PG P        KP+  T  +   TE D 
Sbjct: 865 EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDL 924

Query: 339 EVSLGTPQEVVEAPETPGE 357
                TP+    AP+   E
Sbjct: 925 RT---TPETTTAAPKMTKE 940



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 34/121 (28%), Positives = 46/121 (38%), Gaps = 9/121 (7%)

Query: 237 AMATPAVSGSNSVSRSALFEQQLTKESTPG-PKEP-PVLPSSTCSSKPGPVEPASSQPEE 294
           A  TP  +  N+    A       KE  P  PKEP P  P  T  + P    P + +  E
Sbjct: 665 APTTPKAAAPNTPKEPA---PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK--E 719

Query: 295 AAPTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPET 354
            APT   + +     P    +P      KP  T  +       +E +  TP+E   AP T
Sbjct: 720 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE--PAPTT 777

Query: 355 P 355
           P
Sbjct: 778 P 778


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 46/140 (32%), Positives = 58/140 (41%), Gaps = 23/140 (16%)

Query: 231  PRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEP---------PVLPSSTCSSK 281
            P S  AA+ TP    S + +     E      + P P+EP         P  P+S  ++ 
Sbjct: 1052 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1111

Query: 282  PGPVEPASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGPKPQ-KTEEEVLETEGDQEV 340
            P P EPAS  P  A PTP     E A+P A  P P  P  P P   T EE         V
Sbjct: 1112 PTPEEPAS--PAAAVPTP----EEPASPAAAVPTPEEPAFPAPAVPTPEE----SASAAV 1161

Query: 341  SLGTPQEVVE---APETPGE 357
            ++ TP+E      A  TP E
Sbjct: 1162 AVPTPEESASPAAAVPTPAE 1181



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 45/189 (23%), Positives = 67/189 (35%), Gaps = 21/189 (11%)

Query: 185  FAEYHAVVTCPLPLASSQ-LPVAPQLPVVRQYLARFLEGLALDMGTAPRSLPAAMATPAV 243
            F+   A +   +P+      P  P  P    +     +  A+ + T       A A P  
Sbjct: 951  FSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTP 1010

Query: 244  SGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPTP---- 299
                S + +    ++ T  +   P  PP  P+S  ++ P P EP S  P  A PTP    
Sbjct: 1011 EEPTSPAAAVPTPEEPTSPAAAVP--PPEEPTSPAAAVPTPEEPTS--PAAAVPTPEEPT 1066

Query: 300  -----VPRLSESANPPAQRPDPAHPGG-----PKPQKTEEEVLETEGDQEVSLGTPQEVV 349
                 VP   E  +P A  P P  P       P P++           +E +  +P   V
Sbjct: 1067 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPA--SPAAAV 1124

Query: 350  EAPETPGEP 358
              PE P  P
Sbjct: 1125 PTPEEPASP 1133



 Score = 37.4 bits (85), Expect = 0.021
 Identities = 41/146 (28%), Positives = 53/146 (36%), Gaps = 23/146 (15%)

Query: 231  PRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEP----PVLPS-----STCSSK 281
            P S  AA+ TP    S + +     E      + P P+EP    P +P+     S   + 
Sbjct: 1104 PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAV 1163

Query: 282  PGPVEPASSQPEEAAPTP---------VPRLSESANPPAQRPDPAHPGGPKPQKTEEEVL 332
            P P E AS  P  A PTP         V  L E  +P A  P PA       + T     
Sbjct: 1164 PTPEESAS--PAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAAS 1221

Query: 333  ETEGDQEVSLGTPQEVVEAPETPGEP 358
                ++  SL      V  PE P  P
Sbjct: 1222 VPTSEEPASLAA---AVSNPEEPTSP 1244



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 43/179 (24%), Positives = 63/179 (35%), Gaps = 25/179 (13%)

Query: 190  AVVTCPLPLASSQLPVAPQLPVVRQYLARFLEGLALDMGTAPRSLPAAMATPAVSGSNSV 249
            A V  P P  S+    A   P      A  +  L       P S  A++ TPA       
Sbjct: 1159 AAVAVPTPEESASPAAAVPTPAESASFAAVVATLE-----EPTSPAASVPTPA------- 1206

Query: 250  SRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPT----PVPRLSE 305
            +  A  E+  +  ++    E P   ++  S+   P  PA++ P    PT     V    E
Sbjct: 1207 AMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEE 1266

Query: 306  SANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEV------VEAPETPGEP 358
             ++P A  P P  P  P    +    LE       ++ TP+        V  PE P  P
Sbjct: 1267 LSSPAASVPTPEEPASPAAAVSN---LEEPASPAAAVPTPEVAAIPAASVPTPEVPAIP 1322



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 38/141 (26%), Positives = 52/141 (36%), Gaps = 30/141 (21%)

Query: 242  AVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGP----------VEPASSQ 291
            AV+G +    +      +T+E   G  E PV P++T  +   P           EPAS  
Sbjct: 947  AVAGFSPEWAALAITVPITEED--GTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPAS-- 1002

Query: 292  PEEAAPTP---------VPRLSESANPPAQRPDPAHPGG-----PKPQKTEEEVLETEGD 337
            P  A PTP         VP   E  +P A  P P  P       P P++           
Sbjct: 1003 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTP 1062

Query: 338  QEVSLGTPQEVVEAPETPGEP 358
            +E +  +P   V  PE P  P
Sbjct: 1063 EEPT--SPAAAVPTPEEPTSP 1081


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 47/199 (23%), Positives = 75/199 (37%), Gaps = 28/199 (14%)

Query: 182  PNSFAEYHAVVTCPLPLASSQLPVAPQLPVVRQYLARFLEGLALDMGTAP---------- 231
            P++ A   A  + PLP   + +P +   PV    LA  L   +  +  +P          
Sbjct: 1756 PSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASV 1815

Query: 232  -RSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGP------KEPPVLPS---STCSSK 281
              S+PA+ +  A++ S++ + +      L   STP           P+L S   ST +  
Sbjct: 1816 SASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPT 1875

Query: 282  PGPVEPASSQPEEAAPT--------PVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLE 333
            P P   + + P   APT         VP    SA+ PA  P P     P P    +   +
Sbjct: 1876 PAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQ 1935

Query: 334  TEGDQEVSLGTPQEVVEAP 352
            T    +  L T  +  + P
Sbjct: 1936 THKPVQNPLQTTSQSSKQP 1954



 Score = 32.3 bits (72), Expect = 0.68
 Identities = 40/183 (21%), Positives = 69/183 (37%), Gaps = 18/183 (9%)

Query: 192  VTCPLPLASSQLPVAPQLPVVRQ----YLARFLEGLALDMGTAPRSLPAAMATPAVSGSN 247
            +T    +  +QL   P+   +R+     + +FL     D+   P    A   +      +
Sbjct: 843  ITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDV--RPHHTDANNQSACFEAPD 900

Query: 248  SVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPTPVPRLSESA 307
              + SA  E++++   +   ++  V   S  + KP   +   S+P    P    R  +S 
Sbjct: 901  QKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKP---DEQRSEPSAGIPKVTSRCIDSK 957

Query: 308  NPPAQRPD--PAHPG------GPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEPP 359
             P  +RP+  P   G      GPKP+K  +   ET      S    +EV + P     P 
Sbjct: 958  EP-IERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPI 1016

Query: 360  LSP 362
              P
Sbjct: 1017 KKP 1019



 Score = 32.3 bits (72), Expect = 0.68
 Identities = 27/109 (24%), Positives = 43/109 (39%), Gaps = 9/109 (8%)

Query: 224  ALDMGTAPRSLPAAM--ATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSK 281
            AL   +AP   PAA   A P ++     + +      L   S   P      P+ T  S 
Sbjct: 1867 ALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPA-----PAPTPVSA 1921

Query: 282  PGPVEPASSQPEEAAPTPVPRLSESANPPAQRPDPA--HPGGPKPQKTE 328
            P P  PA +Q +     PV    ++ +  +++P P+   P    P  T+
Sbjct: 1922 PNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTD 1970



 Score = 28.9 bits (63), Expect = 7.6
 Identities = 32/107 (29%), Positives = 38/107 (35%), Gaps = 10/107 (9%)

Query: 257  QQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPTPVPRLSESANPPAQRPDP 316
            QQ    ++  P     LP ST +S P     ++S P  A  TPVP  S SA  PA    P
Sbjct: 1738 QQAQSSASVPPLASAPLPPSTSASVPA----STSAPLPATLTPVP-ASTSAPVPASTLAP 1792

Query: 317  --AHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEPPLS 361
              A    P P      +        VS   P     A  T    P S
Sbjct: 1793 VLASTSAPVP---ASPLAPVSASASVSASVPASTSAAAITSSSAPAS 1836


>gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 41/130 (31%), Positives = 50/130 (38%), Gaps = 20/130 (15%)

Query: 238 MATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPV-EPASSQPEEAA 296
           MA PA     SV   A           P P   PV P+S     PGPV +P   QP+ A 
Sbjct: 575 MARPAAPALTSVPAPA---------PAPTPTPTPVQPTSP---PPGPVAQPTGPQPQSAG 622

Query: 297 PTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPG 356
            T  P    +  PP   P P  P GP P     ++  +      SL   Q +V  P  PG
Sbjct: 623 STSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS-----TSLLAAQSLVPPPGLPG 677

Query: 357 E--PPLSPGF 364
              P + P F
Sbjct: 678 SSTPGVLPYF 687


>gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 41/130 (31%), Positives = 50/130 (38%), Gaps = 20/130 (15%)

Query: 238 MATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPV-EPASSQPEEAA 296
           MA PA     SV   A           P P   PV P+S     PGPV +P   QP+ A 
Sbjct: 575 MARPAAPALTSVPAPA---------PAPTPTPTPVQPTSP---PPGPVAQPTGPQPQSAG 622

Query: 297 PTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPG 356
            T  P    +  PP   P P  P GP P     ++  +      SL   Q +V  P  PG
Sbjct: 623 STSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS-----TSLLAAQSLVPPPGLPG 677

Query: 357 E--PPLSPGF 364
              P + P F
Sbjct: 678 SSTPGVLPYF 687


>gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 41/130 (31%), Positives = 50/130 (38%), Gaps = 20/130 (15%)

Query: 238 MATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPV-EPASSQPEEAA 296
           MA PA     SV   A           P P   PV P+S     PGPV +P   QP+ A 
Sbjct: 575 MARPAAPALTSVPAPA---------PAPTPTPTPVQPTSP---PPGPVAQPTGPQPQSAG 622

Query: 297 PTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPG 356
            T  P    +  PP   P P  P GP P     ++  +      SL   Q +V  P  PG
Sbjct: 623 STSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS-----TSLLAAQSLVPPPGLPG 677

Query: 357 E--PPLSPGF 364
              P + P F
Sbjct: 678 SSTPGVLPYF 687


>gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo
           sapiens]
          Length = 677

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 41/130 (31%), Positives = 50/130 (38%), Gaps = 20/130 (15%)

Query: 238 MATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPV-EPASSQPEEAA 296
           MA PA     SV   A           P P   PV P+S     PGPV +P   QP+ A 
Sbjct: 436 MARPAAPALTSVPAPA---------PAPTPTPTPVQPTSP---PPGPVAQPTGPQPQSAG 483

Query: 297 PTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPG 356
            T  P    +  PP   P P  P GP P     ++  +      SL   Q +V  P  PG
Sbjct: 484 STSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS-----TSLLAAQSLVPPPGLPG 538

Query: 357 E--PPLSPGF 364
              P + P F
Sbjct: 539 SSTPGVLPYF 548


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 35/137 (25%), Positives = 54/137 (39%), Gaps = 10/137 (7%)

Query: 231 PRSLPAAMATPAVSGSNSVSR----SALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVE 286
           P  +PA  A P  + +         S L          PGP +PP  P    S+KP   +
Sbjct: 446 PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP--PQQPGSAKPPSQQ 503

Query: 287 PASSQPEEAAPTPV---PRLSESANPPAQRPDPAHPGGPKPQKTEEEVLE-TEGDQEVSL 342
           P S++P    P P    P+   S  PP+Q+P  A P   +P   +    + T+   +   
Sbjct: 504 PGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGS 563

Query: 343 GTPQEVVEAPETPGEPP 359
           G P +      +  +PP
Sbjct: 564 GKPLQPPTVSPSAKQPP 580



 Score = 36.2 bits (82), Expect = 0.047
 Identities = 34/138 (24%), Positives = 55/138 (39%), Gaps = 26/138 (18%)

Query: 231 PRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASS 290
           P + P+ +  P      +V      +  +    T  P   P+ P+   + + G  +P+S 
Sbjct: 331 PPAQPSGLTKPLAQQPGTV------KPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE 384

Query: 291 QPEEAAPTPVPRLSESANPPAQRPDPAHP-----GGPKPQKTEEEVLETEGDQEVSLGTP 345
           QP   A    P + ++   PAQ+P PA P     G PKP             Q+  L +P
Sbjct: 385 QPGPKALAQPPGVGKT---PAQQPGPAKPPTQQVGTPKPLA-----------QQPGLQSP 430

Query: 346 QEVVEAPETPGEPPLSPG 363
            +     +TP + P  PG
Sbjct: 431 AKAPGPTKTPVQQP-GPG 447



 Score = 35.4 bits (80), Expect = 0.081
 Identities = 38/158 (24%), Positives = 59/158 (37%), Gaps = 36/158 (22%)

Query: 195  PLPLASSQLPVAPQLPVVRQYLARFLEGLALDMGT---APRSLPAAMATPAVSGSNSVSR 251
            P P A   +P   Q P  ++   RF    +L++G+   AP+S P       V+G      
Sbjct: 881  PRPTAGQTVPTPQQSPKPQEQSRRF----SLNLGSITDAPKSQPTT-PQETVTGKLFGFG 935

Query: 252  SALFEQQLTKEST-------------------PGPKEPPVLPSSTCSSKPGPVEPASSQP 292
            +++F Q     ST                   P P +PP       S+   P  PA S  
Sbjct: 936  ASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKS-- 993

Query: 293  EEAAPTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEE 330
                   +P   E+  P A++ +P     P  ++TE E
Sbjct: 994  -------IPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 36/124 (29%), Positives = 52/124 (41%), Gaps = 32/124 (25%)

Query: 261 KESTPGPKEPPVLPSSTCSSKPGPVEPASSQP--EEAAPTPVPRLSESAN---PPAQRP- 314
           K S P P +PP+        +P P +P + QP  E++ P P    ++ +    P AQ+P 
Sbjct: 295 KPSLPSPSKPPI-------QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPG 347

Query: 315 -------------DPAHPGGP-KP--QKTEEEVLETEGDQEVSLGTPQEVVEAPET---P 355
                         PA P GP KP  Q+T  E   +E     +L  P  V + P     P
Sbjct: 348 TVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGP 407

Query: 356 GEPP 359
            +PP
Sbjct: 408 AKPP 411



 Score = 32.0 bits (71), Expect = 0.89
 Identities = 32/133 (24%), Positives = 47/133 (35%), Gaps = 11/133 (8%)

Query: 235  PAAMATPAVSGSNSVSRSALFEQQ---LTKESTPGPKEPPVLPSSTCSSKPGPVEPASSQ 291
            P   ATP      ++  +A+       +T+  T  P   P  PSS  S       P  S+
Sbjct: 2448 PVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSK 2507

Query: 292  PEEAAPTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEA 351
            P  A    +P+L  +     Q+P   HP       T    L      +  L +P     +
Sbjct: 2508 PPIAPKPVIPQLPTT----TQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSP----TS 2559

Query: 352  PETPGEPPLSPGF 364
            P +P     SP F
Sbjct: 2560 PLSPHSNKSSPRF 2572



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 36/145 (24%), Positives = 59/145 (40%), Gaps = 11/145 (7%)

Query: 220 LEGLALDMGTAPRSLPAAMATPAVSGSNSVSRSAL---FEQQLTKESTPGPKEPPVLPSS 276
           LEG  L  G A     AA A    SG+ S S +A+    E  L++ S    ++   + S 
Sbjct: 7   LEGEGLPEGLAA----AAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSR 62

Query: 277 TCSSKPGPVEPASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGP-KPQKTEEEVLETE 335
                 G V PA++   E+      +  +S++PP Q   P  PG P +P  ++    +T 
Sbjct: 63  AQGLPKGSVPPAAA---ESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTF 119

Query: 336 GDQEVSLGTPQEVVEAPETPGEPPL 360
             ++   G     +   E+     L
Sbjct: 120 RSEQKLPGRSPSTISLKESKSRTDL 144



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 33/138 (23%), Positives = 53/138 (38%), Gaps = 22/138 (15%)

Query: 207 PQLPVVRQYLA---RFLEGLALDMGTAPRSLPAAMATPAVSGSNSVSRSALFEQQLT--- 260
           P L  V+++L    +    L  D+   P S    + T  V+ +++VS+S+   QQ +   
Sbjct: 627 PHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKK 686

Query: 261 --------------KESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPTPVPRLSES 306
                         K+  P  K+P +  S +  +K  P   + S+P       VP  SE 
Sbjct: 687 DAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVP--SEQ 744

Query: 307 ANPPAQRPDPAHPGGPKP 324
              P     P  P   KP
Sbjct: 745 DKAPVADDKPKQPKMVKP 762



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 26/111 (23%), Positives = 44/111 (39%), Gaps = 9/111 (8%)

Query: 261 KESTPGPKEPPVLPSSTCSSKPG--PVEPASSQPEEAAPTPV------PRLSESANPPAQ 312
           K   PG  +P   P+ T  +     P++  +S+P+      V      P L   + PP Q
Sbjct: 248 KSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQ 307

Query: 313 RPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEPPLSPG 363
           +P P  P   +P   + +    +   + S G  + + + P T   P   PG
Sbjct: 308 QPTPGKPPAQQPGHEKSQPGPAKPPAQPS-GLTKPLAQQPGTVKPPVQPPG 357



 Score = 28.9 bits (63), Expect = 7.6
 Identities = 22/67 (32%), Positives = 27/67 (40%), Gaps = 4/67 (5%)

Query: 262  ESTPGPKEPPVLPS-STCSSKPGPVEPASSQPEEAAPTPVPRLSESANPPAQRPDP---A 317
            +  P  + P   PS S+  +KP P   +SS    A P P P       PP   P P    
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428

Query: 318  HPGGPKP 324
             P  PKP
Sbjct: 2429 PPTSPKP 2435


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 35/137 (25%), Positives = 54/137 (39%), Gaps = 10/137 (7%)

Query: 231 PRSLPAAMATPAVSGSNSVSR----SALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVE 286
           P  +PA  A P  + +         S L          PGP +PP  P    S+KP   +
Sbjct: 446 PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP--PQQPGSAKPPSQQ 503

Query: 287 PASSQPEEAAPTPV---PRLSESANPPAQRPDPAHPGGPKPQKTEEEVLE-TEGDQEVSL 342
           P S++P    P P    P+   S  PP+Q+P  A P   +P   +    + T+   +   
Sbjct: 504 PGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGS 563

Query: 343 GTPQEVVEAPETPGEPP 359
           G P +      +  +PP
Sbjct: 564 GKPLQPPTVSPSAKQPP 580



 Score = 36.2 bits (82), Expect = 0.047
 Identities = 34/138 (24%), Positives = 55/138 (39%), Gaps = 26/138 (18%)

Query: 231 PRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASS 290
           P + P+ +  P      +V      +  +    T  P   P+ P+   + + G  +P+S 
Sbjct: 331 PPAQPSGLTKPLAQQPGTV------KPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE 384

Query: 291 QPEEAAPTPVPRLSESANPPAQRPDPAHP-----GGPKPQKTEEEVLETEGDQEVSLGTP 345
           QP   A    P + ++   PAQ+P PA P     G PKP             Q+  L +P
Sbjct: 385 QPGPKALAQPPGVGKT---PAQQPGPAKPPTQQVGTPKPLA-----------QQPGLQSP 430

Query: 346 QEVVEAPETPGEPPLSPG 363
            +     +TP + P  PG
Sbjct: 431 AKAPGPTKTPVQQP-GPG 447



 Score = 35.4 bits (80), Expect = 0.081
 Identities = 38/158 (24%), Positives = 59/158 (37%), Gaps = 36/158 (22%)

Query: 195  PLPLASSQLPVAPQLPVVRQYLARFLEGLALDMGT---APRSLPAAMATPAVSGSNSVSR 251
            P P A   +P   Q P  ++   RF    +L++G+   AP+S P       V+G      
Sbjct: 881  PRPTAGQTVPTPQQSPKPQEQSRRF----SLNLGSITDAPKSQPTT-PQETVTGKLFGFG 935

Query: 252  SALFEQQLTKEST-------------------PGPKEPPVLPSSTCSSKPGPVEPASSQP 292
            +++F Q     ST                   P P +PP       S+   P  PA S  
Sbjct: 936  ASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKS-- 993

Query: 293  EEAAPTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEE 330
                   +P   E+  P A++ +P     P  ++TE E
Sbjct: 994  -------IPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 36/124 (29%), Positives = 52/124 (41%), Gaps = 32/124 (25%)

Query: 261 KESTPGPKEPPVLPSSTCSSKPGPVEPASSQP--EEAAPTPVPRLSESAN---PPAQRP- 314
           K S P P +PP+        +P P +P + QP  E++ P P    ++ +    P AQ+P 
Sbjct: 295 KPSLPSPSKPPI-------QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPG 347

Query: 315 -------------DPAHPGGP-KP--QKTEEEVLETEGDQEVSLGTPQEVVEAPET---P 355
                         PA P GP KP  Q+T  E   +E     +L  P  V + P     P
Sbjct: 348 TVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGP 407

Query: 356 GEPP 359
            +PP
Sbjct: 408 AKPP 411



 Score = 32.0 bits (71), Expect = 0.89
 Identities = 32/133 (24%), Positives = 47/133 (35%), Gaps = 11/133 (8%)

Query: 235  PAAMATPAVSGSNSVSRSALFEQQ---LTKESTPGPKEPPVLPSSTCSSKPGPVEPASSQ 291
            P   ATP      ++  +A+       +T+  T  P   P  PSS  S       P  S+
Sbjct: 2448 PVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSK 2507

Query: 292  PEEAAPTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEA 351
            P  A    +P+L  +     Q+P   HP       T    L      +  L +P     +
Sbjct: 2508 PPIAPKPVIPQLPTT----TQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSP----TS 2559

Query: 352  PETPGEPPLSPGF 364
            P +P     SP F
Sbjct: 2560 PLSPHSNKSSPRF 2572



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 36/145 (24%), Positives = 59/145 (40%), Gaps = 11/145 (7%)

Query: 220 LEGLALDMGTAPRSLPAAMATPAVSGSNSVSRSAL---FEQQLTKESTPGPKEPPVLPSS 276
           LEG  L  G A     AA A    SG+ S S +A+    E  L++ S    ++   + S 
Sbjct: 7   LEGEGLPEGLAA----AAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSR 62

Query: 277 TCSSKPGPVEPASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGP-KPQKTEEEVLETE 335
                 G V PA++   E+      +  +S++PP Q   P  PG P +P  ++    +T 
Sbjct: 63  AQGLPKGSVPPAAA---ESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTF 119

Query: 336 GDQEVSLGTPQEVVEAPETPGEPPL 360
             ++   G     +   E+     L
Sbjct: 120 RSEQKLPGRSPSTISLKESKSRTDL 144



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 33/138 (23%), Positives = 53/138 (38%), Gaps = 22/138 (15%)

Query: 207 PQLPVVRQYLA---RFLEGLALDMGTAPRSLPAAMATPAVSGSNSVSRSALFEQQLT--- 260
           P L  V+++L    +    L  D+   P S    + T  V+ +++VS+S+   QQ +   
Sbjct: 627 PHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKK 686

Query: 261 --------------KESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPTPVPRLSES 306
                         K+  P  K+P +  S +  +K  P   + S+P       VP  SE 
Sbjct: 687 DAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVP--SEQ 744

Query: 307 ANPPAQRPDPAHPGGPKP 324
              P     P  P   KP
Sbjct: 745 DKAPVADDKPKQPKMVKP 762



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 26/111 (23%), Positives = 44/111 (39%), Gaps = 9/111 (8%)

Query: 261 KESTPGPKEPPVLPSSTCSSKPG--PVEPASSQPEEAAPTPV------PRLSESANPPAQ 312
           K   PG  +P   P+ T  +     P++  +S+P+      V      P L   + PP Q
Sbjct: 248 KSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQ 307

Query: 313 RPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEPPLSPG 363
           +P P  P   +P   + +    +   + S G  + + + P T   P   PG
Sbjct: 308 QPTPGKPPAQQPGHEKSQPGPAKPPAQPS-GLTKPLAQQPGTVKPPVQPPG 357



 Score = 28.9 bits (63), Expect = 7.6
 Identities = 22/67 (32%), Positives = 27/67 (40%), Gaps = 4/67 (5%)

Query: 262  ESTPGPKEPPVLPS-STCSSKPGPVEPASSQPEEAAPTPVPRLSESANPPAQRPDP---A 317
            +  P  + P   PS S+  +KP P   +SS    A P P P       PP   P P    
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428

Query: 318  HPGGPKP 324
             P  PKP
Sbjct: 2429 PPTSPKP 2435


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 5/99 (5%)

Query: 265  PGPKEPPVLPSSTCSSKPGPVEPASSQ-PEEAAPTPVPRLSESANPPAQRPDPAHPGGPK 323
            P PK  P LP++T SSK GP  P+S + P   A TP  +   +  PP+ +  PA P  PK
Sbjct: 1341 PSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP-SPK 1399

Query: 324  PQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEPPLSP 362
               T   V+     +  +    +   E   TP +  L+P
Sbjct: 1400 GDPTSPAVIPLSPKKAPATPVTR---EGAATPSKGDLTP 1435



 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 43/137 (31%), Positives = 60/137 (43%), Gaps = 22/137 (16%)

Query: 230  APRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTC-SSKPGPVEPA 288
            +P+  PAA  TP   G+++   +     + +  +TP PK  P  P++T  S K GP  P+
Sbjct: 1018 SPKGSPAA--TPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPS 1075

Query: 289  SSQPEEAAPTPVPRLSESANPPAQRPDPAHP---GGPKPQKTEEEVLETEGDQEVSLGTP 345
                 + APTP      +A PP+ +  PA P   G P P         T    +  L TP
Sbjct: 1076 L----KGAPTP-----PAATPPSPKGGPATPSPKGAPMPPAA------TPPSPKGGLATP 1120

Query: 346  QEVVEAPETPGEPPLSP 362
                 AP TP   P SP
Sbjct: 1121 PH-KGAPTTPAATPPSP 1136



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 43/161 (26%), Positives = 61/161 (37%), Gaps = 20/161 (12%)

Query: 221  EGLALDMGTAPRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSS 280
            +G        P S    +ATP   G+ +   +A         +TP PK  P  P++T  S
Sbjct: 1146 KGAPTTPAATPPSPKGGLATPPPKGAPTTP-AATPPSPKGGLATPSPKGAPTTPAATPPS 1204

Query: 281  KPG----------PVEPASS--QPEEAAPTPVPR---LSESANPPAQRPDPAHP---GGP 322
              G          P  PA++   P+    TP P+    + +A PP+ +  PA P   G P
Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAP 1264

Query: 323  KPQKTEEEVLETEGDQEVSLGTPQEVVEAPETP-GEPPLSP 362
             P       L+         G P   V  P +P G P  SP
Sbjct: 1265 TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP 1305



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 48/176 (27%), Positives = 62/176 (35%), Gaps = 35/176 (19%)

Query: 206  APQLPVVRQYLARFLEGLALDMGTAPRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTP 265
            AP  PV R+  A   +G        P SL  A AT A  G                 +TP
Sbjct: 1415 APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG---------------PATP 1459

Query: 266  GPKEPPVLPSSTCSSKPGPVEP----ASSQPEEAAPTPVP------------RLSESANP 309
              K  P LP+ T  S   P  P     SS P++A  TP P               E    
Sbjct: 1460 SSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPAT 1519

Query: 310  PAQRPDPAHPGGPKPQKTEEEVL---ETEGDQEVSLGTPQEVVEAPETPGEPPLSP 362
            P+ R DP  P      K     L   E      +++ +P++    P TP E P +P
Sbjct: 1520 PSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIP-TPKEAPATP 1574



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 38/131 (29%), Positives = 49/131 (37%), Gaps = 17/131 (12%)

Query: 235  PAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEE 294
            PA    PA+S ++S  + A         +TP PK  P  P    S K  P  PA++ P  
Sbjct: 903  PAPKQAPALSMTSSSPKKA--------RATPAPKGIPASP----SPKGAPTPPAATPPSP 950

Query: 295  AAPTPVPRLSESANPPAQRPDPAHPGG---PKPQKTEEEVLETEGDQEVSLGTPQEVVEA 351
                  P    +  PPA  P P+  GG   P P+        T    +    TP     A
Sbjct: 951  KGGPATPSPKWAPTPPAATP-PSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP-KGA 1008

Query: 352  PETPGEPPLSP 362
            P  P   P SP
Sbjct: 1009 PTPPAVTPPSP 1019



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 48/184 (26%), Positives = 67/184 (36%), Gaps = 21/184 (11%)

Query: 195  PLPLASSQLPVA-PQLPVVRQYLARFLEGLALDMGTAPRSLPAAMATPAVSGSNSVSRSA 253
            P P  +S  P A P  P          +G          S     ATP++ G+ +   +A
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPP-AA 1085

Query: 254  LFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPT------PVPRLSESA 307
                     +TP PK  P+ P++T    P P    ++ P + APT      P P+   + 
Sbjct: 1086 TPPSPKGGPATPSPKGAPMPPAAT---PPSPKGGLATPPHKGAPTTPAATPPSPKGGLAT 1142

Query: 308  NPPAQRP------DPAHPGG---PKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEP 358
             PP   P       P+  GG   P P+        T    +  L TP     AP TP   
Sbjct: 1143 PPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSP-KGAPTTPAAT 1201

Query: 359  PLSP 362
            P SP
Sbjct: 1202 PPSP 1205



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 55/197 (27%), Positives = 74/197 (37%), Gaps = 35/197 (17%)

Query: 182  PNSFAEYHAVVTCPLPL---ASSQLPVAPQLPVVRQYLARFLEGLALDMGTAPRSLPAAM 238
            P+  A   AVVT P P    A+S    AP  P       +   G     G AP   P A+
Sbjct: 1282 PHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKG-APT--PPAV 1338

Query: 239  ATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPT 298
              P+  G+ ++  +           TP  K  P  P    SSK GP  PA++   +  P 
Sbjct: 1339 TPPSPKGTPTLPAT-----------TPSSKGGPTTP----SSKEGPTPPAATPSHKGGPA 1383

Query: 299  PVPRLSESANP--PAQRPDPAHPG----GPK-----PQKTEEEVLETEGDQEVSLGTPQE 347
              P  S    P  P+ + DP  P      PK     P   E     ++GD      TP  
Sbjct: 1384 MTPP-SPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVS 1442

Query: 348  VVEAPET--PGEPPLSP 362
            + +AP T  P   P +P
Sbjct: 1443 LKKAPATSAPKGGPATP 1459



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 43/176 (24%), Positives = 65/176 (36%), Gaps = 16/176 (9%)

Query: 190  AVVTCPLPLASSQLPVAPQLPVVRQYLARFLEGLALDMGTAPRSLPAAMATPAVSGSNSV 249
            +VV  P P      P   Q P +    +   +  A     AP+ +PA+   P+  G+ + 
Sbjct: 889  SVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATP---APKGIPAS---PSPKGAPTP 942

Query: 250  SRSALFEQQLTKESTPGPKEPPVLPSSTCSS-KPGPVEPA--SSQPEEAAPTPVPRLSES 306
              +A         +TP PK  P  P++T  S K GP  P+   +    AA  P P+   +
Sbjct: 943  P-AATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPA 1001

Query: 307  ANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEPPLSP 362
               P   P P     P P+ +       +G       TP      P   G P  +P
Sbjct: 1002 TPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP------PSPKGSPAATP 1051



 Score = 35.8 bits (81), Expect = 0.062
 Identities = 32/99 (32%), Positives = 42/99 (42%), Gaps = 20/99 (20%)

Query: 265  PGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGPKP 324
            P PKE P  PSS  +S P  V P++    + AP+P     E   PPA          P P
Sbjct: 1565 PTPKEAPATPSSKEASSPPAVTPST---YKGAPSP----KELLIPPAVT-------SPSP 1610

Query: 325  QKTEEEVLETEGDQEVSLGTPQEVVEAPE-TPGEPPLSP 362
            ++       T    E    TP     AP+ TP  PP++P
Sbjct: 1611 KEAPTPPAVTPPSPEKGPATP-----APKGTPTSPPVTP 1644



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 36/130 (27%), Positives = 49/130 (37%), Gaps = 32/130 (24%)

Query: 234  LPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKE---PPVLPSSTCSSKPGPVE---- 286
            +P AM  P      S  ++          +TP  KE   PP +  ST    P P E    
Sbjct: 1549 IPPAMTVP------SPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIP 1602

Query: 287  PASSQPE-EAAPTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTP 345
            PA + P  + APTP      +  PP+    PA P  PK   T   V            TP
Sbjct: 1603 PAVTSPSPKEAPTP-----PAVTPPSPEKGPATP-APKGTPTSPPV------------TP 1644

Query: 346  QEVVEAPETP 355
              + ++P +P
Sbjct: 1645 SSLKDSPTSP 1654



 Score = 32.3 bits (72), Expect = 0.68
 Identities = 39/173 (22%), Positives = 56/173 (32%), Gaps = 32/173 (18%)

Query: 221  EGLALDMGTAPRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSS 280
            +G        P S    +ATP+  G+ +   +A         +TP PK  P  P++T  S
Sbjct: 1215 KGAPTTPAATPPSPKGGLATPSPKGAPTTP-AATPPSPKGGPATPPPKGAPTPPAATPPS 1273

Query: 281  --------------------KPGPVEPASSQPEEAAPTPV------PRLSESANPPAQRP 314
                                 P P    ++ P + APTP       P+ S    PP   P
Sbjct: 1274 LKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAP 1333

Query: 315  DPAHPGGPKPQKTEEEVLETEGDQ-----EVSLGTPQEVVEAPETPGEPPLSP 362
             P     P P+ T      T   +       S   P      P   G P ++P
Sbjct: 1334 TPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTP 1386


>gi|22749387 zinc finger, CCHC domain containing 5 [Homo sapiens]
          Length = 475

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 54/209 (25%), Positives = 81/209 (38%), Gaps = 25/209 (11%)

Query: 106 TFDGSPWLLDRFLAQLGDYMSFHFEHYQDNISRVCEILRRLTGRAQAWAAPYLDGDLPLP 165
           TF G    L  FL QL  YM      Y    + V  +    +GRA  W    LD   PL 
Sbjct: 243 TFSGDSQKLPEFLVQLYSYMRVRGHLYPTEAALVSFVGNCFSGRAGWWFQLLLDIQSPLL 302

Query: 166 DDYELFCQDLKEVVQDPNSFAEYHAVVTCPLPLASSQLPVAPQLPVVRQYL--------A 217
           +  E F   L++   +P +  + +    C   L   +  VA    ++ Q L         
Sbjct: 303 EQCESFIPVLQDTFDNPENMKDAN---QCIHQLCQGEGHVATHFHLIAQELNWDESTLWI 359

Query: 218 RFLEGLALDMGTAPRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSST 277
           +F EGLA           +++       S + + S L  Q ++ E  P P   P+  SS+
Sbjct: 360 QFQEGLA-----------SSIQDELSHTSPATNLSDLITQCISLEEKPDPN--PLGKSSS 406

Query: 278 CSSKPGPVEPASSQPEEAAPTPVPRLSES 306
                    PA +QP +AA    P +SE+
Sbjct: 407 AEGDGPESPPAENQPMQAA-INCPHISEA 434



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 38/152 (25%), Positives = 54/152 (35%), Gaps = 38/152 (25%)

Query: 231 PRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASS 290
           P+ LP  M  PA            +E Q T E    P++PP  P         P EP ++
Sbjct: 61  PQKLPEHMNPPAA-----------WEAQKTPEFKE-PQKPPE-PQDLL-----PWEPPAA 102

Query: 291 QPEEAAPTPVPRLSESANPPAQRPDPAH----------PGGPKPQKTEEEVLETEGDQEV 340
              + AP     L+  A   +Q+P  AH          P   +     +E   +E     
Sbjct: 103 WELQEAPAAPESLAPPATRESQKPPMAHEIPTVLEGQGPANTQDATIAQEPKNSEPQDPP 162

Query: 341 SLGTPQEVVEAPET----------PGEPPLSP 362
           ++  PQE  E  ET          P + PL P
Sbjct: 163 NIEKPQEAPEYQETAAQLEFLELPPPQEPLEP 194


>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
          Length = 808

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 40/151 (26%), Positives = 55/151 (36%), Gaps = 17/151 (11%)

Query: 229 TAPRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTP-GPKEP-PVLPSSTCSSKPGPVE 286
           +AP   PA    PAV+GS  V  +     +  K   P GP+ P P   +   +S+     
Sbjct: 70  SAPAPAPAPAPAPAVTGSTVVVLTLEASPEAPKPQLPSGPESPEPAAVAGVETSRALAAG 129

Query: 287 PASSQPEEAAPTPVPRLSESANPPAQRPDPAHPG--------GPKPQKTEEEVL------ 332
             S + EEA P+P P        P + P    PG         PKP  T    +      
Sbjct: 130 ADSPKTEEARPSPAPGPGTPTGTPTRTPSRTAPGALTAKPPLAPKPGTTVASGVTARSAS 189

Query: 333 -ETEGDQEVSLGTPQEVVEAPETPGEPPLSP 362
            +  G    +  T     +APE P  P   P
Sbjct: 190 GQVTGGHGAAAATSASAGQAPEDPSGPGTGP 220



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 5/61 (8%)

Query: 268 KEPPVLPSSTCSSKPGPVEPASSQPEEAAPTPVPRLSESANPPAQRP----DPAHPGGPK 323
           ++PP+ PSS+  S PG ++   S+    AP+P P +  ++  PA  P    +  HP  P 
Sbjct: 649 QQPPLGPSSSLLSLPG-LKSRGSRAAGGAPSPPPPVRRASAGPAPGPVVTAEGLHPSLPS 707

Query: 324 P 324
           P
Sbjct: 708 P 708



 Score = 33.1 bits (74), Expect = 0.40
 Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 5/99 (5%)

Query: 265 PGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGPK- 323
           PG   P  +P S  +S P P  PA +       + V  L+  A+P A  P P  P GP+ 
Sbjct: 55  PGEARPAWVPGSAETSAPAPA-PAPAPAPAVTGSTVVVLTLEASPEA--PKPQLPSGPES 111

Query: 324 PQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEPPLSP 362
           P+      +ET         +P +  EA  +P   P +P
Sbjct: 112 PEPAAVAGVETSRALAAGADSP-KTEEARPSPAPGPGTP 149


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 37/137 (27%), Positives = 53/137 (38%), Gaps = 25/137 (18%)

Query: 204 PVAPQLPVVRQYLARF--------LEGLALD---MGTAPRSLPAAMATPAVSGSNSVSRS 252
           P++P   VV+Q  ++F        +E   L       AP+S PA  A P           
Sbjct: 854 PLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKP----------- 902

Query: 253 ALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPTPVPRLSESANPPAQ 312
              + Q +    P P  PP  P S+    P P  P  + P    PT  P   +S +P  +
Sbjct: 903 ---KWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKK 959

Query: 313 RPDPAHPGGPKPQKTEE 329
               + PGG KP  T +
Sbjct: 960 TSKTSSPGGKKPPPTPQ 976



 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 36/128 (28%), Positives = 46/128 (35%), Gaps = 8/128 (6%)

Query: 240 TPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPTP 299
           TP V  S SV    L          P P  PP   S+    KP P  P  S P+ +AP P
Sbjct: 688 TPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAP--SLPQFSAPPP 745

Query: 300 VPRLSE-----SANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPET 354
             ++ +        PP   P P  P    PQ   + ++            P     AP T
Sbjct: 746 PLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPT 805

Query: 355 PGEPPLSP 362
           P  PP+ P
Sbjct: 806 P-TPPVPP 812



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 42/150 (28%), Positives = 57/150 (38%), Gaps = 24/150 (16%)

Query: 231  PRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASS 290
            P  +PA    P  + S +  +S    ++ +K S+PG K+PP  P    S K       + 
Sbjct: 932  PSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKS---SSGAE 988

Query: 291  QPEEAAPTPVPRLSESANPPAQR--------PDPAHPGGPKPQKTEEEVLETEGDQE--- 339
             PE   P+ V  L     PPA+         P PA P  PKP K     +   G  +   
Sbjct: 989  HPEPKRPS-VDSLVSKFTPPAESGSPSKETLPPPAAP--PKPGKLNLSGVNLPGVLQQGC 1045

Query: 340  VSLGTP-------QEVVEAPETPGEPPLSP 362
            VS   P         VVE P  P +    P
Sbjct: 1046 VSAKAPVLSGRGKDSVVEFPSPPSDSDFPP 1075



 Score = 33.1 bits (74), Expect = 0.40
 Identities = 53/190 (27%), Positives = 68/190 (35%), Gaps = 29/190 (15%)

Query: 195 PLPLASSQLPVAPQLPVVRQYLARFLEGLALDMGTAPRSLPAAMATPAVSGSNSVSRSAL 254
           P P+ +   P AP  P+V       +         AP    AA  TP      +  + A 
Sbjct: 766 PPPIPAPLPPQAPPKPLVT------IPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAF 819

Query: 255 FEQQL--TKESTPGPKEPPVLP--SSTCSS-KPGPVEPASSQPEEAA----PTPVPRLSE 305
               +  +  + P P  PP LP   S C+   P P+ P  S  ++ A    P P P   E
Sbjct: 820 PASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAME 879

Query: 306 S-------ANPPAQRPDPAHPGGPKPQKTEEEVLETE---GDQEVSL---GTPQEVVEAP 352
           S       AN   Q P PA    PK Q +   V   +      E SL     P   V AP
Sbjct: 880 SQPLKPVPANVAPQSP-PAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAP 938

Query: 353 ETPGEPPLSP 362
             P  P  SP
Sbjct: 939 PPPPPPTASP 948



 Score = 29.6 bits (65), Expect = 4.4
 Identities = 23/87 (26%), Positives = 33/87 (37%), Gaps = 16/87 (18%)

Query: 257 QQLTKESTPGPKEPPVLPS--------STCSSKPGPVEPASSQP---EEAAPTPVPRLSE 305
           Q +T+ + P P  PP +P+            + P P    +  P   + A PTP P +  
Sbjct: 753 QHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPP 812

Query: 306 SANPPA-----QRPDPAHPGGPKPQKT 327
           +   PA       P P  P  P P  T
Sbjct: 813 AKKQPAFPASYIPPSPPTPPVPVPPPT 839



 Score = 28.9 bits (63), Expect = 7.6
 Identities = 34/147 (23%), Positives = 49/147 (33%), Gaps = 23/147 (15%)

Query: 231 PRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASS 290
           P +LP   +  A    + +S      +Q+  +  P P  PP + S      P  V P S 
Sbjct: 837 PPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPP-PPTPPAMESQPLKPVPANVAPQSP 895

Query: 291 QPEEAAPT------PVPRLSESANPPAQR-------PDPAHPGGPKPQKTEEEVLETEGD 337
              +A P       PVP       PP          P P     P P  T     +    
Sbjct: 896 PAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKS-- 953

Query: 338 QEVSLGTPQEVVEAPETPG--EPPLSP 362
                G+P +      +PG  +PP +P
Sbjct: 954 -----GSPGKKTSKTSSPGGKKPPPTP 975


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 54/188 (28%), Positives = 70/188 (37%), Gaps = 26/188 (13%)

Query: 193 TCPLPLASSQLPVAPQLPVV----RQYLARFLEGLALDMGTAPRSLPAAMATPAVSGSNS 248
           T P P AS   P   +LP        +L+R LE   L         P    +P      S
Sbjct: 458 TSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLS--------PPPEESPLSPPPES 509

Query: 249 VSRSALFEQQLT--KESTPGPK-EPPVLPSSTCSSKPGPVE--PASSQPEEAAPTPVPRL 303
              S L E  L+  +ES P P  E P+ P    S    P E  P S  PEE   +P P  
Sbjct: 510 SPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEA 569

Query: 304 SESANPPAQRP----DPAHPGGPKPQKTE-----EEVLETEGDQEVSLGTPQEVVEAPET 354
           S  + PP + P        P  P P+ +      EE   +   +E  L  P E       
Sbjct: 570 SRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPP 629

Query: 355 PGEPPLSP 362
           P + P+SP
Sbjct: 630 PEDSPMSP 637



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 27/68 (39%), Positives = 32/68 (47%), Gaps = 8/68 (11%)

Query: 265  PGPKEPPVLPSSTCSSKPGPV-------EPASSQPEEAAPTPVPRLSESANPPAQRPDPA 317
            P P+ PP LP+   +   GPV        P SS  E   P+ +P  S      AQ P P 
Sbjct: 4281 PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLP-PT 4339

Query: 318  HPGGPKPQ 325
            HPG PKPQ
Sbjct: 4340 HPGTPKPQ 4347



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 31/111 (27%), Positives = 44/111 (39%), Gaps = 13/111 (11%)

Query: 264 TPGPKEPPVLPSSTCS-----------SKPGPVEPASSQPEEAAPTPVPRLSESANPPAQ 312
           +P P+E P+ P    S           S P    P S  PEE+  +P P  S  + PP  
Sbjct: 636 SPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPED 695

Query: 313 RP-DPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEPPLSP 362
            P  P     P     E+ ++    ++   L  P+E    P + G P LSP
Sbjct: 696 SPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG-PHLSP 745



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 35/130 (26%), Positives = 46/130 (35%), Gaps = 10/130 (7%)

Query: 245 GSNSVSRSALFEQQLTKEST--PGPKEPPVLP--SSTCSSKPGPVEPASSQPEEAAPTPV 300
           G   V      E  L +E    P P+E P+ P    + +S P      S  PEE   +P+
Sbjct: 420 GKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPL 479

Query: 301 PRLSESANP----PAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAP--ET 354
           P     + P    P   P    P  P P+ +    LE           P   +E P    
Sbjct: 480 PEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPP 539

Query: 355 PGEPPLSPGF 364
           P   PLSP F
Sbjct: 540 PEASPLSPPF 549



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 15/109 (13%)

Query: 264 TPGPKEPPV--LPSSTCSSKPGPVEPASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGG 321
           +P  +EP +  +P   C S        S Q EE   +P P  S   +P  ++P    P  
Sbjct: 807 SPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESH-LSPELEKP----PLS 861

Query: 322 PKPQKTEEEVLETEGDQEVSLGTPQEVVE--------APETPGEPPLSP 362
           P+P+K  EE  +    +E+ L  P             A   PGEPPLSP
Sbjct: 862 PRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSP 910



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 33/102 (32%), Positives = 43/102 (42%), Gaps = 13/102 (12%)

Query: 264 TPGPKEPPVLPSSTCSSKPGPVE--PASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGG 321
           +P P+E P+ P    S    P E  P S  PEE+  +P P  S  + PP   P       
Sbjct: 582 SPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPM-----S 636

Query: 322 PKPQKTEEEVLETEGDQEVSLGTPQEVV-EAPETPGEPPLSP 362
           P P+++           EVS  +P  VV      P E PLSP
Sbjct: 637 PPPEESP-----MSPPPEVSRLSPLPVVSRLSPPPEESPLSP 673



 Score = 35.8 bits (81), Expect = 0.062
 Identities = 31/103 (30%), Positives = 40/103 (38%), Gaps = 10/103 (9%)

Query: 267 PKEPPVLPSSTCSSKP-----GPVEPASSQP--EEAAPTPVPRLSESANPPAQRPDPAHP 319
           PKEP  L    C +KP       +EP    P  EE    P P  S  + PP + P    P
Sbjct: 406 PKEPGPLQ---CEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPP 462

Query: 320 GGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEPPLSP 362
              +     EE+  +   + + L  P E       P E PLSP
Sbjct: 463 EASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSP 505



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 30/99 (30%), Positives = 41/99 (41%), Gaps = 18/99 (18%)

Query: 264 TPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGPK 323
           +P P++PP  P    + +  P+ P   +P  +     P LSE   PP           P 
Sbjct: 861 SPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPL---------SPL 911

Query: 324 PQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEPPLSP 362
           P   EE  L   G+  +S   PQ +   P  P  PPLSP
Sbjct: 912 P---EELPLSPSGEPSLS---PQLM---PPDPLPPPLSP 941



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 35/137 (25%), Positives = 49/137 (35%), Gaps = 14/137 (10%)

Query: 237 AMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCS--SKPGPVEPASSQPEE 294
           A+ TP      +   S  FE+      +P P+E P  P    S  S P    P S  PEE
Sbjct: 531 ALETPLSPPPEASPLSPPFEES---PLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEE 587

Query: 295 AAPTPVPRLSES---------ANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTP 345
           +  +P P  S           + PP + P    P   +     E+   +   +E  +  P
Sbjct: 588 SPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPP 647

Query: 346 QEVVEAPETPGEPPLSP 362
            EV      P    LSP
Sbjct: 648 PEVSRLSPLPVVSRLSP 664



 Score = 32.7 bits (73), Expect = 0.52
 Identities = 31/122 (25%), Positives = 43/122 (35%), Gaps = 20/122 (16%)

Query: 252 SALFEQQLTKESTPGPKEPPVLPSSTCS-----------SKPGPVEPASSQPEEAAPTPV 300
           S LF        +P P+E P+ P    S           S P    P S  PE +  +P+
Sbjct: 597 SRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPL 656

Query: 301 PRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEPPL 360
           P +S  + PP + P    P         EE   +   +   L  P E       P + P 
Sbjct: 657 PVVSRLSPPPEESPLSPPP---------EESPTSPPPEASRLSPPPEDSPTSPPPEDSPA 707

Query: 361 SP 362
           SP
Sbjct: 708 SP 709



 Score = 32.7 bits (73), Expect = 0.52
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 15/117 (12%)

Query: 227  MGTAPRSLPAAMA-TPAVSGSNSVSRSALFEQQLTKES-TPGPKEPP-----VLPSSTCS 279
            +G  P+  P A A  P+      + R   +     +   TP P+ PP      LP  +  
Sbjct: 2345 LGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLP 2404

Query: 280  SKPGPVEPASSQPEEAAPTPV-PR-LSESA------NPPAQRPDPAHPGGPKPQKTE 328
            S P    PAS Q + ++ +P+ PR LS  A       P  Q PDP      +PQ  +
Sbjct: 2405 SDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRD 2461



 Score = 32.0 bits (71), Expect = 0.89
 Identities = 31/102 (30%), Positives = 42/102 (41%), Gaps = 4/102 (3%)

Query: 264 TPGPKEPPVLPSSTCS-SKPGPVEPASSQPEEAAPTPVPRLSESANPPAQRPDPAHP--G 320
           +P P+E P+ P    S + P P     S P E +PT  P     A+PP +    + P   
Sbjct: 663 SPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEE 722

Query: 321 GPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEPPLSP 362
            P     EE  L    +       P+E   +P  P EP LSP
Sbjct: 723 SPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPR-PEEPHLSP 763



 Score = 32.0 bits (71), Expect = 0.89
 Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 2/63 (3%)

Query: 251  RSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASSQP-EEAAPTPVPRLSESANP 309
            +S L    L K+ +P P EPP   S T +     V   S+ P EE +P P P     A+P
Sbjct: 4870 KSQLDILSLLKQESPAP-EPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASP 4928

Query: 310  PAQ 312
            P +
Sbjct: 4929 PTE 4931



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 55/229 (24%), Positives = 82/229 (35%), Gaps = 39/229 (17%)

Query: 144  RRLTGRAQAW--AAPYLDGDLPLPDDYELFCQDLKEVVQDPNSFAEYHAVVTCPLPLASS 201
            R+L G +QA+   APY  G LPL    +   Q  +        FA             S+
Sbjct: 2789 RQLVGGSQAFYQRAPY-PGSLPLQQQQQQLWQQQQATAATSMRFA------------MSA 2835

Query: 202  QLPVAPQLPVVRQYLARFLEGLALDMGTAPRSLPAAMATPAVSGSNSVSRSALFEQQLTK 261
            + P  P   + RQ L   L G++  +      +P   A PA      +      ++ L  
Sbjct: 2836 RFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGP-AGPA----QFIELRHNVQKGLGP 2890

Query: 262  ESTPGPKE-PPVLPSS-TCSSKPGPVEPASSQ--------PEEAAPTPVPRLSESANPPA 311
              TP P + PP  P     S  P  + P   +        P++ +  P P L+ S +P  
Sbjct: 2891 GGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTP 2950

Query: 312  QRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEV-VEAPETPGEPP 359
                P  P G +        L         LG P  + +EA + P E P
Sbjct: 2951 HTKGPTLPTGLE--------LVNRPPSSTELGRPNPLALEAGKLPCEDP 2991



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 33/129 (25%), Positives = 49/129 (37%), Gaps = 31/129 (24%)

Query: 264 TPGPKEPPVLPSSTCSS-KPGPVEPASSQPEE---AAPTP-------------------V 300
           +P P+E P  P    S   P P +  +S P E   A+P P                    
Sbjct: 672 SPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEE 731

Query: 301 PRLSESANPPAQRPDPAHPG-GPKPQ------KTEEEVLETEGDQEVSLGTPQEVVEAPE 353
           P+L   +  P   P P  P   P+P+      + EE  L  + ++      P+E   +P+
Sbjct: 732 PQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQ 791

Query: 354 TPGEPPLSP 362
             G P LSP
Sbjct: 792 AEG-PHLSP 799



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 11/97 (11%)

Query: 241  PAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGP-VEPASSQPEEA---- 295
            P    S + + S L  +QL   S P P+EP   PS    S   P  EP    P E     
Sbjct: 4888 PPTQHSYTYNVSNLDVRQL---SAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEP 4944

Query: 296  -APTPVPRLS--ESANPPAQRPDPAHPGGPKPQKTEE 329
              P+P+P  S  ESA P  +   P      +P + ++
Sbjct: 4945 PVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKK 4981


>gi|194239681 tubulin tyrosine ligase-like family, member 10 isoform
           1 [Homo sapiens]
          Length = 673

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 29/84 (34%), Positives = 36/84 (42%), Gaps = 1/84 (1%)

Query: 271 PVLPSSTCSSKPGPVEPASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEE 330
           P LP+    S   P+  A  QP    P P P + +   PP    D AH G P+   TE+ 
Sbjct: 586 PPLPTRQAKSSGPPMPHAPDQPGARRPAPPPLVPQRPRPPGPDLDSAHDGEPQAPGTEQS 645

Query: 331 -VLETEGDQEVSLGTPQEVVEAPE 353
                   QE S GT +E  E PE
Sbjct: 646 GTGNRHPAQEPSPGTAKEEREEPE 669


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 35/119 (29%), Positives = 50/119 (42%), Gaps = 18/119 (15%)

Query: 253 ALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPTPV---------PRL 303
           A F    +K  +P P  P +   +     PGPV    + P+ + PTP          P +
Sbjct: 668 APFSPPPSKPRSPNPAAPALAAPAVV---PGPVSTTDASPQ-SPPTPQTTLTPLQESPVI 723

Query: 304 SESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEPPLSP 362
           S+  +PP   P   HP  P P K  E V+E     E    T +E ++ P  P  PP +P
Sbjct: 724 SKDQSPPPSPPPSYHP-PPPPTKKPEVVVEAPSASE----TAEEPLQDPNWPPPPPPAP 777



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 39/141 (27%), Positives = 58/141 (41%), Gaps = 18/141 (12%)

Query: 230 APRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGP-KEPPVL-------PSSTCSSK 281
           +P     A+A PAV      +  A  +   T ++T  P +E PV+       PS   S  
Sbjct: 679 SPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYH 738

Query: 282 PGPVEPASSQPEEAAPTPVPRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVS 341
           P P  P + +PE     P    SE+A  P Q P+   P  P P++ +  + +    +E  
Sbjct: 739 PPP--PPTKKPEVVVEAP--SASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAF 794

Query: 342 LGTPQEVVEAPETPGEPPLSP 362
                  V +PE P  P  SP
Sbjct: 795 FS-----VASPE-PAGPSGSP 809



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 41/157 (26%), Positives = 59/157 (37%), Gaps = 22/157 (14%)

Query: 222 GLALDMGTAPRSLPAAMATPAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSK 281
           G +   GT P   P  +A P  S   +        +++T   +PG      L +S CSS 
Sbjct: 583 GYSSQSGT-PTLPPKGLAGPPASPGKAQPPKP---ERVTSLRSPGASVSSSL-TSLCSSS 637

Query: 282 PGPVEPASSQPEEAAPT-------PVPRLSESANPPAQRP---DPAHPGGPKPQKTEEEV 331
             P     S P+   P        P P++    +PP  +P   +PA P    P      V
Sbjct: 638 SDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPV 697

Query: 332 LETEGDQEVSLGTPQEVV----EAP--ETPGEPPLSP 362
             T+   + S  TPQ  +    E+P       PP SP
Sbjct: 698 STTDASPQ-SPPTPQTTLTPLQESPVISKDQSPPPSP 733


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.133    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,557,040
Number of Sequences: 37866
Number of extensions: 1226417
Number of successful extensions: 12537
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 296
Number of HSP's successfully gapped in prelim test: 1137
Number of HSP's that attempted gapping in prelim test: 7099
Number of HSP's gapped (non-prelim): 4608
length of query: 364
length of database: 18,247,518
effective HSP length: 104
effective length of query: 260
effective length of database: 14,309,454
effective search space: 3720458040
effective search space used: 3720458040
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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