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Search of human proteins with 42544130
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
(639 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 1369 0.0
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 1273 0.0
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens] 1122 0.0
gi|160707881 formin 2 [Homo sapiens] 136 5e-32
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 127 3e-29
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 120 5e-27
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 116 7e-26
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 116 7e-26
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 115 9e-26
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 115 9e-26
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 115 9e-26
gi|42544127 splicing factor 1 isoform 4 [Homo sapiens] 112 8e-25
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 112 1e-24
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 108 2e-23
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 107 3e-23
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 105 1e-22
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 105 1e-22
gi|47132519 Ras association and pleckstrin homology domains 1 is... 105 2e-22
gi|150417989 cyclin K isoform 1 [Homo sapiens] 105 2e-22
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 103 4e-22
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 103 6e-22
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 102 1e-21
gi|163965366 nascent polypeptide-associated complex alpha subuni... 101 2e-21
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 100 3e-21
gi|45827712 quaking homolog, KH domain RNA binding isoform HQK-7... 100 5e-21
gi|45827710 quaking homolog, KH domain RNA binding isoform HQK-7... 100 5e-21
gi|45827708 quaking homolog, KH domain RNA binding isoform HQK-6... 100 5e-21
gi|45827706 quaking homolog, KH domain RNA binding isoform HQK-5... 100 5e-21
gi|18959210 WIRE protein [Homo sapiens] 100 7e-21
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 99 1e-20
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 1369 bits (3544), Expect = 0.0
Identities = 639/639 (100%), Positives = 639/639 (100%)
Query: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED 60
MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED
Sbjct: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED 60
Query: 61 LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN 120
LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN
Sbjct: 61 LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN 120
Query: 121 PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK 180
PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK
Sbjct: 121 PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK 180
Query: 181 GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240
GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR
Sbjct: 181 GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240
Query: 241 KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP 300
KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP
Sbjct: 241 KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP 300
Query: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS 360
QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS
Sbjct: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS 360
Query: 361 TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP
Sbjct: 361 TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
Query: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP
Sbjct: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
Query: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS 540
PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS
Sbjct: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS 540
Query: 541 IPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPP 600
IPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPP
Sbjct: 541 IPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPP 600
Query: 601 PPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPPPQN 639
PPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPPPQN
Sbjct: 601 PPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPPPQN 639
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 1273 bits (3294), Expect = 0.0
Identities = 599/612 (97%), Positives = 601/612 (98%)
Query: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED 60
MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED
Sbjct: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED 60
Query: 61 LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN 120
LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN
Sbjct: 61 LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN 120
Query: 121 PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK 180
PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK
Sbjct: 121 PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK 180
Query: 181 GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240
GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR
Sbjct: 181 GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240
Query: 241 KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP 300
KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP
Sbjct: 241 KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP 300
Query: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS 360
QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS
Sbjct: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS 360
Query: 361 TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP
Sbjct: 361 TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
Query: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP
Sbjct: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
Query: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS 540
PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS
Sbjct: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS 540
Query: 541 IPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPP 600
IPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMM P
Sbjct: 541 IPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPR 600
Query: 601 PPPPPPMDPSNF 612
P + +F
Sbjct: 601 GGDGPSHESEDF 612
Score = 65.1 bits (157), Expect = 2e-10
Identities = 58/183 (31%), Positives = 67/183 (36%), Gaps = 43/183 (23%)
Query: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS 540
P P G P + PL + PPPPS + + PW ++G
Sbjct: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWM--------NSGPSE 375
Query: 541 IPPWQQQQAAAAASPGAPQMQGNPTMVPLP--------PGVQPPLPPGAPPPP---PPPP 589
P+ PG G P P P G P PPPP PPPP
Sbjct: 376 SRPYHGMHGGGPGGPG-----GGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPP 430
Query: 590 PGSAGMMYAPPPPP----PPPMDPSNFVTMMGMGV------AGM---PPFGM-PPAPPPP 635
P + G P PP PPPMD T +G GV GM PP GM PP PPPP
Sbjct: 431 PMNQG-----PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPP 485
Query: 636 PPQ 638
Q
Sbjct: 486 SGQ 488
Score = 32.0 bits (71), Expect = 1.8
Identities = 37/143 (25%), Positives = 40/143 (27%), Gaps = 45/143 (31%)
Query: 264 PWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEA 323
PWQ NTT T G G I P Q A A
Sbjct: 524 PWQQ-------NTTTTTTSAGTGSIP-------PWQQQQA-----------------AAA 552
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMH 383
P + P PL +P P PPPP PP S P G
Sbjct: 553 ASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPP--------PPPPGSAGMMIPPRGG-- 602
Query: 384 GGGPGGPGGGPHSFPHPLPSLTG 406
GP FP PL +L G
Sbjct: 603 ----DGPSHESEDFPRPLVTLPG 621
>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
Length = 548
Score = 1122 bits (2903), Expect = 0.0
Identities = 528/536 (98%), Positives = 529/536 (98%)
Query: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED 60
MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED
Sbjct: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED 60
Query: 61 LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN 120
LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN
Sbjct: 61 LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN 120
Query: 121 PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK 180
PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK
Sbjct: 121 PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK 180
Query: 181 GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240
GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR
Sbjct: 181 GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240
Query: 241 KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP 300
KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP
Sbjct: 241 KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP 300
Query: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS 360
QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS
Sbjct: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS 360
Query: 361 TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP
Sbjct: 361 TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
Query: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP
Sbjct: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
Query: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSA 536
PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQ + A
Sbjct: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQRSLPAAAMA 536
Score = 68.2 bits (165), Expect = 2e-11
Identities = 57/180 (31%), Positives = 66/180 (36%), Gaps = 42/180 (23%)
Query: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS 540
P P G P + PL + PPPPS + + PW ++G
Sbjct: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWM--------NSGPSE 375
Query: 541 IPPWQQQQAAAAASPGAPQMQGNPTMVPLP--------PGVQPPLPPGAPPPP---PPPP 589
P+ PG G P P P G P PPPP PPPP
Sbjct: 376 SRPYHGMHGGGPGGPG-----GGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPP 430
Query: 590 PGSAGMMYAPPPPP----PPPMDPSNFVTMMGMGV------AGM---PPFGMPPAPPPPP 636
P + G P PP PPPMD T +G GV GM PP GM P PPPPP
Sbjct: 431 PMNQG-----PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPP 485
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 136 bits (343), Expect = 5e-32
Identities = 124/362 (34%), Positives = 146/362 (40%), Gaps = 70/362 (19%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMH 383
P+P + S+S P L P P P P+L ST +PP + P +
Sbjct: 860 PLPCTESSSSMPG---LGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLP 916
Query: 384 GGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQG--PHPPGH 441
G G P P + PLP L G G P P P P PPPPP+ P PP
Sbjct: 917 GAGIPPPPPLPGAGILPLPPLPG--AGIP----PPPPLPGAAIPPPPPLPGAGIPLPPPL 970
Query: 442 HG----PPPMDQYLGSTP----VGSGVYRLH--QGKGMMPPPPM---GMMPPPPPPPSGQ 488
G PPP G P G+G+ G G+ PPPP+ G+ PPPP P +G
Sbjct: 971 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1030
Query: 489 PPPPP----SGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPW 544
PPPPP P PP PPPPP P + + PLP G G PP
Sbjct: 1031 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP------------GAGIPPPP 1078
Query: 545 QQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPP----GAPPPPP------PPPPGSAG 594
A P P G P PLP PP PP G PPPPP PPPP G
Sbjct: 1079 PLPGAGIPPPPPLPG-AGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1137
Query: 595 MMYAPPP-------PPPPPMDPSNFVTMMGMGVAGMPP------FGMPPAPP------PP 635
PPP PPPPP+ + + AG+PP G+PP PP PP
Sbjct: 1138 AGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPP 1197
Query: 636 PP 637
PP
Sbjct: 1198 PP 1199
Score = 130 bits (326), Expect = 5e-30
Identities = 116/347 (33%), Positives = 131/347 (37%), Gaps = 87/347 (25%)
Query: 324 PVPASVGSTSGPATTPLASA----PRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPY 379
P P + + P PL A P P A PPPP L PP + P
Sbjct: 943 PPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP- 1001
Query: 380 HGMHGGG----PGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQ----PPPPP 431
+ G G P PG G P P P G P PPPP + PPPPP
Sbjct: 1002 -PLPGAGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1057
Query: 432 MNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM---GMMPPPPPPPSGQ 488
+ PP PPP+ G G+ PPPP+ G+ PPPP P +G
Sbjct: 1058 LPGAGIPP----PPPLP-----------------GAGIPPPPPLPGAGIPPPPPLPGAGI 1096
Query: 489 PPPPPSG----PLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPW 544
PPPPP P PP PPPPP P + + PLP G G PP
Sbjct: 1097 PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP------------GAGIPPPP 1144
Query: 545 QQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPP----GAPPPPP------PPPPGSAG 594
+ P P G P PLP PP PP G PPPPP PPPP G
Sbjct: 1145 PLPRVGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPG 1203
Query: 595 MMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPP----PPP 637
PPPP P GMG+ PP PP PPP PPP
Sbjct: 1204 AGIPPPPPLP------------GMGI---PPAPAPPLPPPGTGIPPP 1235
Score = 110 bits (276), Expect = 3e-24
Identities = 100/311 (32%), Positives = 121/311 (38%), Gaps = 53/311 (17%)
Query: 378 PYHGMHGGGPGGPGG--GPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPM--- 432
P G+ G P PG GP + SL +Q + + P QPPPPP
Sbjct: 759 PVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLW 818
Query: 433 NQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM------------GMMPP 480
+ G PG P + ++ S + PPP+ GM+PP
Sbjct: 819 SAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPP 878
Query: 481 PPPPPSGQPPPP-PSGPLP---PWQQQQQQPPPPPP-PSSSMASSTPLPWQQNTTTTTTS 535
PPPP G P PS +P P Q + PPPPPP P + + PLP
Sbjct: 879 PPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGA-GILPLPPL 937
Query: 536 AGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPP----GAPPPPP----- 586
G G PP AA P P G P PLP PP PP G PPPPP
Sbjct: 938 PGAGIPPPPPLPGAAIPPPPPLPGA-GIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 996
Query: 587 -PPPPGSAGMMYAPPP-------PPPPPMDPSNFVTMMGMGVAGMPP------FGMPPAP 632
PPPP G PPP PPPPP+ + + AG+PP G+PP P
Sbjct: 997 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1056
Query: 633 P------PPPP 637
P PPPP
Sbjct: 1057 PLPGAGIPPPP 1067
Score = 105 bits (261), Expect = 2e-22
Identities = 105/322 (32%), Positives = 124/322 (38%), Gaps = 60/322 (18%)
Query: 324 PVPASVGSTSGPATTPLASA----PRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPY 379
P+P + P PL A P P A PPPP L PP + P
Sbjct: 965 PLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP- 1023
Query: 380 HGMHGGG----PGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQ----PPPPP 431
+ G G P PG G P P P G P PPPP + PPPPP
Sbjct: 1024 -PLPGAGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1079
Query: 432 MNQG--PHPPGHHG----PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM---GMMPPPP 482
+ P PP G PPP +G P G G+ PPPP+ G+ PPPP
Sbjct: 1080 LPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP-----LPGAGIPPPPPLPGAGIPPPPP 1134
Query: 483 PPPSGQPPPPPSG----PLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGT 538
P +G PPPPP P PP PPPPP P + + PLP G
Sbjct: 1135 LPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGV-GIPPPPPLPGV 1193
Query: 539 GSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPP---GAPPPP------PP-- 587
G PP A P P + G + +PP PPLPP G PPPP PP
Sbjct: 1194 GIPPP---PPLPGAGIPPPPPLPG----MGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLL 1246
Query: 588 PPPGSAGMM------YAPPPPP 603
P GS+ + + PPP P
Sbjct: 1247 PQVGSSTLPTPQVCGFLPPPLP 1268
Score = 75.5 bits (184), Expect = 1e-13
Identities = 76/263 (28%), Positives = 95/263 (36%), Gaps = 107/263 (40%)
Query: 468 GMMPPPPMGMMPPPPP-PPS-----------------------------------GQPPP 491
G++ PP+ +P PP PP QPPP
Sbjct: 753 GVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPP 812
Query: 492 PPSGPLPPWQQQQQQPPPPPPPSSS--------------------MASSTPLPWQQNTTT 531
PPS W Q QP PP S S + S PLP T +
Sbjct: 813 PPS---LLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPC---TES 866
Query: 532 TTTSAGTGSIPP-------WQQQQAAAAASPGAPQMQGNPTMVPLPP-----GVQPPLP- 578
+++ G G +PP + A P P +QG + P PP G+ PP P
Sbjct: 867 SSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPL 926
Query: 579 -----------PGAPPPPPPPPPGSAGMMYAPPPPPPP----PMDPSNFVTMMGMGVAGM 623
PGA PPPPP PG+A PPPPP P P+ P + G G+
Sbjct: 927 PGAGILPLPPLPGAGIPPPPPLPGAA----IPPPPPLPGAGIPLPP----PLPGAGIPPP 978
Query: 624 PPF---GMPPAPP------PPPP 637
PP G+PP PP PPPP
Sbjct: 979 PPLPGAGIPPPPPLPGAGIPPPP 1001
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 127 bits (319), Expect = 3e-29
Identities = 113/352 (32%), Positives = 130/352 (36%), Gaps = 55/352 (15%)
Query: 311 KEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPP-PPSLMSTTQSRPPWM 369
+E SL+A + P GP + P P N P PP Q PP
Sbjct: 26 EESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 85
Query: 370 NSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPP-----PW 424
+ P P PG P G P P P GPPP P
Sbjct: 86 GNKPQGPPP--------PGKPQGPP-------PQGDKSRSPRSPPGKPQGPPPQGGNQPQ 130
Query: 425 MQPPPPPMNQGPHPPGHH---GPPPMDQYLGSTPVGSGVYRLHQ---GKGMMPPPPMGMM 478
PPPP QGP P G + GPPP + G P G R + GK PPP G
Sbjct: 131 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQ 190
Query: 479 PPPPPPPSGQP--PPP-----PSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTT 531
P PPPP G+P PPP P GP PP + Q PPP + S ++ +P Q
Sbjct: 191 PQGPPPPPGKPQGPPPQGGNKPQGPPPP---GKPQGPPPQGDNKSQSARSPPGKPQGPPP 247
Query: 532 TTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPG-VQPPLPPG--------AP 582
+ G PP + Q G P GN P PPG Q P P G +P
Sbjct: 248 QGGNQPQGPPPPPGKPQ-------GPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300
Query: 583 PPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPP 634
P P PP G P PPPPP P G G PP G P PPP
Sbjct: 301 PGKPQGPPPQGGNQ--PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 350
Score = 122 bits (307), Expect = 8e-28
Identities = 114/341 (33%), Positives = 125/341 (36%), Gaps = 74/341 (21%)
Query: 344 PRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPL-- 401
P P PPP S + PP GP P G GP P G P P P
Sbjct: 92 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP---PQGGNQPQGPPPPPGKPQG-PPPQGG 147
Query: 402 -----PSLTGGHGGHPMQHN------------PNGPPP-----PWMQPPPPPMNQGPHPP 439
P G G P Q + P GPPP P PPPP QGP P
Sbjct: 148 NKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 207
Query: 440 GHH---GPPPMDQYLGSTPVG---SGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQP--PP 491
G + GPPP + G P G S R GK PPP G P PPPP G+P PP
Sbjct: 208 GGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 267
Query: 492 P-----PSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQ 546
P P GP PP + Q PPP S S +S +P Q + G PP +
Sbjct: 268 PQGGNKPQGPPPPGKPQG---PPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGK 324
Query: 547 QQAAAAASPGAPQMQGNPTMVPLPPGV-QPPLPPG--------APPPPPPPPPGSAGMMY 597
Q G P GN P PPG Q P P G +PP P PP G
Sbjct: 325 PQ-------GPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNP 377
Query: 598 APPPPPP--PPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPP 636
PPPP P P PP G P PP PP
Sbjct: 378 QGPPPPAGGNPQQPQ------------APPAGQPQGPPRPP 406
Score = 103 bits (258), Expect = 4e-22
Identities = 95/302 (31%), Positives = 105/302 (34%), Gaps = 61/302 (20%)
Query: 322 EAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHG 381
+ P P GP P P P PP S + PP GP P G
Sbjct: 140 QGPPPQGGNKPQGP--------PPPGKPQGPPPQGDNKSRSSRSPPGKPQGPP---PQGG 188
Query: 382 MHGGGPGGPGGGPHSFPHPL-------PSLTGGHGGHPMQHN------------PNGPPP 422
GP P G P P P P G G P Q + P GPPP
Sbjct: 189 NQPQGPPPPPGKPQG-PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPP 247
Query: 423 -----PWMQPPPPPMNQGPHPPGHH---GPPPMDQYLGSTPVGSGVYRLHQ---GKGMMP 471
P PPPP QGP P G + GPPP + G P G R + GK P
Sbjct: 248 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGP 307
Query: 472 PPPMGMMPPPPPPPSGQP--PPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNT 529
PP G P PPPP G+P PPP G P +P PPP S + S P
Sbjct: 308 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSP----- 362
Query: 530 TTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQP---PLPPGAPPPPP 586
G PP Q+ P A GNP PP QP P PP P
Sbjct: 363 ------PGKPQGPPQQEGNNPQGPPPPAG---GNPQQPQAPPAGQPQGPPRPPQGGRPSR 413
Query: 587 PP 588
PP
Sbjct: 414 PP 415
Score = 80.5 bits (197), Expect = 4e-15
Identities = 77/239 (32%), Positives = 83/239 (34%), Gaps = 72/239 (30%)
Query: 402 PSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGH-HGPPPMDQYLGSTPVGSGV 460
PSL G NP G PP P P P PPG GPPP G+ P G
Sbjct: 29 PSLIAG--------NPQGAPPQGGNKPQGP----PSPPGKPQGPPPQG---GNQPQG--- 70
Query: 461 YRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASS 520
PPPPP Q PPP G P Q PPPP P
Sbjct: 71 -------------------PPPPPGKPQGPPPQGGNKP------QGPPPPGKPQG----- 100
Query: 521 TPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPG 580
P P + + + G PP Q G Q QG P P P Q P P G
Sbjct: 101 -PPPQGDKSRSPRSPPGKPQGPPPQ----------GGNQPQGPP---PPPGKPQGPPPQG 146
Query: 581 APPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPP--FGMPPAPPPPPP 637
P PPPPG P PPP D + + G PP G P PPPPP
Sbjct: 147 GNKPQGPPPPGK-------PQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPP 198
Score = 54.3 bits (129), Expect = 3e-07
Identities = 43/111 (38%), Positives = 47/111 (42%), Gaps = 18/111 (16%)
Query: 545 QQQQAAAAASP-GAPQMQGN-PTMVPLPPGV-QPPLPPGAP----PPPPP-----PPPGS 592
++ + A +P GAP GN P P PPG Q P P G PPPPP PPP
Sbjct: 26 EESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 85
Query: 593 AGMMYAPPPP-----PPPPMDPSNFVTMMGMGVAGMPPFG-MPPAPPPPPP 637
PPPP PPP D S G PP G P PPPPP
Sbjct: 86 GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 136
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 120 bits (300), Expect = 5e-27
Identities = 111/347 (31%), Positives = 127/347 (36%), Gaps = 72/347 (20%)
Query: 311 KEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMN 370
+E SL+A + P P GP P P P PPP + Q PP
Sbjct: 26 EESPSLIAGNPQGPSPQGGNKPQGPP-------PPPGKPQG--PPPQGGNKPQGPPP--- 73
Query: 371 SGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPP 430
G + P G P P G P P GG+ P GPPPP +P P
Sbjct: 74 PGKPQGPPPQGDKSRSPRSPPGKPQG-----PPPQGGN-------QPQGPPPPPGKPQGP 121
Query: 431 PMNQGPHPPGHHGPPPMDQYLGSTPVG--SGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQ 488
P G P GPPP + G P G S R GK PPP G P PPPP G+
Sbjct: 122 PPQGGNRP---QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK 178
Query: 489 P--PPP-----PSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSI 541
P PPP P GP PP + Q PPP S +S +P Q + G
Sbjct: 179 PQGPPPQGGKKPQGPPPPGKPQG----PPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPP 234
Query: 542 PPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPG----------APPPPPPPPPG 591
PP + Q G P GN P PPG +P PP +PP P PP
Sbjct: 235 PPPGKPQ-------GPPPQGGNKPQGPPPPG-KPQGPPAQGGSKSQSARSPPGKPQGPPQ 286
Query: 592 SAGMMYAPPPPPP--PPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPP 636
G PPPP P P PP G P PP PP
Sbjct: 287 QEGNNPQGPPPPAGGNPQQPQ------------APPAGQPQGPPRPP 321
Score = 74.7 bits (182), Expect = 2e-13
Identities = 77/270 (28%), Positives = 89/270 (32%), Gaps = 57/270 (21%)
Query: 297 PGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTP------------LASAP 344
PG PQ + + S + + P P GP P P
Sbjct: 74 PGKPQGPPPQGDKSRSPRSPPGK-PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGP 132
Query: 345 RPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPL--- 401
P PPP S + PP GP P G GP P G P P P
Sbjct: 133 PPPGKPQGPPPQGDKSRSPRSPPGKPQGPP---PQGGNQPQGPPPPPGKPQG-PPPQGGK 188
Query: 402 ----PSLTGGHGGHPMQHN-----------PNGPPP-----PWMQPPPPPMNQGPHPPGH 441
P G G P Q + P GPPP P PPPP QGP P G
Sbjct: 189 KPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 248
Query: 442 H---GPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLP 498
+ GPPP + G G + + PP PP + Q PPPP+G P
Sbjct: 249 NKPQGPPPPGKPQGPPAQGGS-----KSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNP 303
Query: 499 PWQQQQQQPP------PPPPPSSSMASSTP 522
QQ Q PP PP PP S P
Sbjct: 304 ---QQPQAPPAGQPQGPPRPPQGGRPSRPP 330
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 116 bits (290), Expect = 7e-26
Identities = 107/337 (31%), Positives = 129/337 (38%), Gaps = 71/337 (21%)
Query: 321 GEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPS--ESRP 378
G PVP S G SGP P P PP P + S S PP + S P +S P
Sbjct: 148 GRFPVP-SPGHRSGP--------PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP 198
Query: 379 YHGMHGGGPGGP-GGGPHSFPHPLPSLTG-GHGGHPMQHNPNGPPPPWMQPPPPPMNQGP 436
++ PGGP P P P P G GG ++ +P P+ PP P P
Sbjct: 199 HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT--P 256
Query: 437 HPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP------PPPPPSGQPP 490
PPP PPPP+G P PPPPP P
Sbjct: 257 SRALDDKPPP------------------------PPPPVGNRPSIHREAVPPPPPQNNKP 292
Query: 491 PPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAA 550
P PS P P Q PPPPPPP S PLP +S+G P Q+ +
Sbjct: 293 PVPSTPRP--SASSQAPPPPPPP--SRPGPPPLP--------PSSSGNDETPRLPQRNLS 340
Query: 551 AAASPGAPQMQGNPTMVPLPPGVQPPL----PPGAPPPPPPPPPGSAGMMYAPPPPPPPP 606
++S G +P PP +PP PPG P PPPPP S + P P
Sbjct: 341 LSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQ 400
Query: 607 MDPSNFVTMMGMGVAGMPPFGMPP------APPPPPP 637
+ + V G PP +PP APPPPPP
Sbjct: 401 LPSRSGVDSPRSG--PRPP--LPPDRPSAGAPPPPPP 433
Score = 89.0 bits (219), Expect = 1e-17
Identities = 99/361 (27%), Positives = 120/361 (33%), Gaps = 104/361 (28%)
Query: 346 PAAPANNPPPPSLMSTTQSRPPWMN----------------------------SGPSESR 377
P P PPPP + + P +N S P +
Sbjct: 2 PVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDK 61
Query: 378 P-----------YHGMHGGGPGGPGGGPHSFPHPLPSLTGG--HGGHPM------QHNPN 418
P + G G G GG GGG SF P GG G P + N +
Sbjct: 62 PKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDS 121
Query: 419 GPPPPWMQPP----------PPPMNQGPHP---PGHHGPPPMDQYLGSTPVGSGVYRLHQ 465
G P + PP PP G P PGH PP Q
Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQ---------------- 165
Query: 466 GKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPP--PSSSMASSTPL 523
+ MPPP P P PPP PS P P + PP P P TP
Sbjct: 166 -RNRMPPP----RPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPP 220
Query: 524 PWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPP 583
P+ N T + G GSI +Q +++SP P PLPP P P
Sbjct: 221 PFPGNRGT---ALGGGSI----RQSPLSSSSP----FSNRP---PLPP--TPSRALDDKP 264
Query: 584 PPPPPPPGSAGMMYAPPPPPPPPMD-----PSNFVTMMGMGVAGMPPFGMPPAPPPPPPQ 638
PPPPPP G+ ++ PPPPP + PS PP P PPP PP
Sbjct: 265 PPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPS 324
Query: 639 N 639
+
Sbjct: 325 S 325
Score = 68.9 bits (167), Expect = 1e-11
Identities = 87/343 (25%), Positives = 105/343 (30%), Gaps = 100/343 (29%)
Query: 324 PVPASVGSTSGPATTPLASAPRP--AAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHG 381
P VGS P+ S PRP ++P N PP Q P GP+ P+ G
Sbjct: 171 PPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSP-----GPTPP-PFPG 224
Query: 382 MHGGGPGG--------PGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQ------- 426
G GG P S PLP + P PPPP
Sbjct: 225 NRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPS----RALDDKPPPPPPPVGNRPSIHRE 280
Query: 427 --PPPPPMNQGPH------------------PPGHHGPPPMDQYLGSTPVGSGVYRLHQG 466
PPPPP N P PP GPPP+ S+ RL Q
Sbjct: 281 AVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPP---SSSGNDETPRLPQR 337
Query: 467 K----------------GMMPPPPMGMMPPP---PPPPSGQPPPPP-------------- 493
G +PPPP PPP PP SG PPPP
Sbjct: 338 NLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPA 397
Query: 494 --------------SGP---LPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSA 536
SGP LPP + PPPPPP +S P + +
Sbjct: 398 TPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFH 457
Query: 537 GTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPP 579
+PP + + P + + PPLPP
Sbjct: 458 PISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPP 500
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 116 bits (290), Expect = 7e-26
Identities = 107/337 (31%), Positives = 129/337 (38%), Gaps = 71/337 (21%)
Query: 321 GEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPS--ESRP 378
G PVP S G SGP P P PP P + S S PP + S P +S P
Sbjct: 148 GRFPVP-SPGHRSGP--------PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP 198
Query: 379 YHGMHGGGPGGP-GGGPHSFPHPLPSLTG-GHGGHPMQHNPNGPPPPWMQPPPPPMNQGP 436
++ PGGP P P P P G GG ++ +P P+ PP P P
Sbjct: 199 HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT--P 256
Query: 437 HPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP------PPPPPSGQPP 490
PPP PPPP+G P PPPPP P
Sbjct: 257 SRALDDKPPP------------------------PPPPVGNRPSIHREAVPPPPPQNNKP 292
Query: 491 PPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAA 550
P PS P P Q PPPPPPP S PLP +S+G P Q+ +
Sbjct: 293 PVPSTPRP--SASSQAPPPPPPP--SRPGPPPLP--------PSSSGNDETPRLPQRNLS 340
Query: 551 AAASPGAPQMQGNPTMVPLPPGVQPPL----PPGAPPPPPPPPPGSAGMMYAPPPPPPPP 606
++S G +P PP +PP PPG P PPPPP S + P P
Sbjct: 341 LSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQ 400
Query: 607 MDPSNFVTMMGMGVAGMPPFGMPP------APPPPPP 637
+ + V G PP +PP APPPPPP
Sbjct: 401 LPSRSGVDSPRSG--PRPP--LPPDRPSAGAPPPPPP 433
Score = 89.0 bits (219), Expect = 1e-17
Identities = 99/361 (27%), Positives = 120/361 (33%), Gaps = 104/361 (28%)
Query: 346 PAAPANNPPPPSLMSTTQSRPPWMN----------------------------SGPSESR 377
P P PPPP + + P +N S P +
Sbjct: 2 PVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDK 61
Query: 378 P-----------YHGMHGGGPGGPGGGPHSFPHPLPSLTGG--HGGHPM------QHNPN 418
P + G G G GG GGG SF P GG G P + N +
Sbjct: 62 PKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDS 121
Query: 419 GPPPPWMQPP----------PPPMNQGPHP---PGHHGPPPMDQYLGSTPVGSGVYRLHQ 465
G P + PP PP G P PGH PP Q
Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQ---------------- 165
Query: 466 GKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPP--PSSSMASSTPL 523
+ MPPP P P PPP PS P P + PP P P TP
Sbjct: 166 -RNRMPPP----RPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPP 220
Query: 524 PWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPP 583
P+ N T + G GSI +Q +++SP P PLPP P P
Sbjct: 221 PFPGNRGT---ALGGGSI----RQSPLSSSSP----FSNRP---PLPP--TPSRALDDKP 264
Query: 584 PPPPPPPGSAGMMYAPPPPPPPPMD-----PSNFVTMMGMGVAGMPPFGMPPAPPPPPPQ 638
PPPPPP G+ ++ PPPPP + PS PP P PPP PP
Sbjct: 265 PPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPS 324
Query: 639 N 639
+
Sbjct: 325 S 325
Score = 68.9 bits (167), Expect = 1e-11
Identities = 87/343 (25%), Positives = 105/343 (30%), Gaps = 100/343 (29%)
Query: 324 PVPASVGSTSGPATTPLASAPRP--AAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHG 381
P VGS P+ S PRP ++P N PP Q P GP+ P+ G
Sbjct: 171 PPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSP-----GPTPP-PFPG 224
Query: 382 MHGGGPGG--------PGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQ------- 426
G GG P S PLP + P PPPP
Sbjct: 225 NRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPS----RALDDKPPPPPPPVGNRPSIHRE 280
Query: 427 --PPPPPMNQGPH------------------PPGHHGPPPMDQYLGSTPVGSGVYRLHQG 466
PPPPP N P PP GPPP+ S+ RL Q
Sbjct: 281 AVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPP---SSSGNDETPRLPQR 337
Query: 467 K----------------GMMPPPPMGMMPPP---PPPPSGQPPPPP-------------- 493
G +PPPP PPP PP SG PPPP
Sbjct: 338 NLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPA 397
Query: 494 --------------SGP---LPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSA 536
SGP LPP + PPPPPP +S P + +
Sbjct: 398 TPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFH 457
Query: 537 GTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPP 579
+PP + + P + + PPLPP
Sbjct: 458 PISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPP 500
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 115 bits (289), Expect = 9e-26
Identities = 124/500 (24%), Positives = 179/500 (35%), Gaps = 58/500 (11%)
Query: 178 RGKGSVKEGKVGRK------DGQMLP--------GEDEPLHALVTANTM--ENVKKAVEQ 221
R +GS+ + GRK DG+ P G + P A ++N E VKK+ ++
Sbjct: 22 RSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKK 81
Query: 222 IRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTK 281
++ +++ + Q + E R + + I RP SE ++ +
Sbjct: 82 VKEEASSPLKSNKRQREKVASDTEEADRTSSK-KTKTQEISRPNSPSEGEGESSDSRSVN 140
Query: 282 CGGAGH---IASDCKFQRPGDPQSAQDKARMD----KEYLSLMAELGEAPVPASVGSTSG 334
G+ I D + P P +++ D ++ L +AP + +S
Sbjct: 141 DEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSA 200
Query: 335 PATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH------GMHGGGPG 388
P TP P P A PP S T S+ P P+ P+ +H P
Sbjct: 201 PPGTPQLPTPGPTPSATAVPPQG--SPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPP 258
Query: 389 GPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPP------PMNQGPHPPGHH 442
P PH PHP G G P + PP PP P P+ Q P PP
Sbjct: 259 SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPF 318
Query: 443 GPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMP--------PPPPPPSGQP--PPP 492
G PP G P+G+ + + P + P PP P P PP
Sbjct: 319 GLPPQASQ-GQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP 377
Query: 493 PSGPLPPWQQQQQQPPPP----PPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQ-- 546
P+ P+P Q PP P P S A+ P P + ++ +T + PP Q
Sbjct: 378 PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 437
Query: 547 -QQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPP 605
Q +SP P +P PP PP G P PP + PPP P
Sbjct: 438 PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT--GLHQVAPQPPFAQHPFVPGGPPPITP 495
Query: 606 PMDPSNFVTMMGMGVAGMPP 625
P PS G G + PP
Sbjct: 496 PTCPSTSTPPAGPGTSAQPP 515
Score = 57.0 bits (136), Expect = 5e-08
Identities = 58/193 (30%), Positives = 70/193 (36%), Gaps = 38/193 (19%)
Query: 444 PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQ 503
P P D S S ++ Q + P G+ P P P G P P GP P
Sbjct: 162 PSPQDNESDSD--SSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTP----S 215
Query: 504 QQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGN 563
PP P++S A + P A T +P QQA A PQ
Sbjct: 216 ATAVPPQGSPTASQAPNQP------------QAPTAPVPHTHIQQAPALH----PQR--- 256
Query: 564 PTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPP-----PMDPSNFVTMMGM 618
PP PP P +P PP P GSAG AP PP P P + +
Sbjct: 257 ------PPSPHPP-PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLL 309
Query: 619 GVAGMP-PFGMPP 630
G P PFG+PP
Sbjct: 310 QHPGPPQPFGLPP 322
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 115 bits (289), Expect = 9e-26
Identities = 124/500 (24%), Positives = 179/500 (35%), Gaps = 58/500 (11%)
Query: 178 RGKGSVKEGKVGRK------DGQMLP--------GEDEPLHALVTANTM--ENVKKAVEQ 221
R +GS+ + GRK DG+ P G + P A ++N E VKK+ ++
Sbjct: 576 RSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKK 635
Query: 222 IRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTK 281
++ +++ + Q + E R + + I RP SE ++ +
Sbjct: 636 VKEEASSPLKSNKRQREKVASDTEEADRTSSK-KTKTQEISRPNSPSEGEGESSDSRSVN 694
Query: 282 CGGAGH---IASDCKFQRPGDPQSAQDKARMD----KEYLSLMAELGEAPVPASVGSTSG 334
G+ I D + P P +++ D ++ L +AP + +S
Sbjct: 695 DEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSA 754
Query: 335 PATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH------GMHGGGPG 388
P TP P P A PP S T S+ P P+ P+ +H P
Sbjct: 755 PPGTPQLPTPGPTPSATAVPPQG--SPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPP 812
Query: 389 GPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPP------PMNQGPHPPGHH 442
P PH PHP G G P + PP PP P P+ Q P PP
Sbjct: 813 SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPF 872
Query: 443 GPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMP--------PPPPPPSGQP--PPP 492
G PP G P+G+ + + P + P PP P P PP
Sbjct: 873 GLPPQASQ-GQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP 931
Query: 493 PSGPLPPWQQQQQQPPPP----PPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQ-- 546
P+ P+P Q PP P P S A+ P P + ++ +T + PP Q
Sbjct: 932 PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 991
Query: 547 -QQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPP 605
Q +SP P +P PP PP G P PP + PPP P
Sbjct: 992 PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT--GLHQVAPQPPFAQHPFVPGGPPPITP 1049
Query: 606 PMDPSNFVTMMGMGVAGMPP 625
P PS G G + PP
Sbjct: 1050 PTCPSTSTPPAGPGTSAQPP 1069
Score = 57.0 bits (136), Expect = 5e-08
Identities = 58/193 (30%), Positives = 70/193 (36%), Gaps = 38/193 (19%)
Query: 444 PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQ 503
P P D S S ++ Q + P G+ P P P G P P GP P
Sbjct: 716 PSPQDNESDSD--SSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTP----S 769
Query: 504 QQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGN 563
PP P++S A + P A T +P QQA A PQ
Sbjct: 770 ATAVPPQGSPTASQAPNQP------------QAPTAPVPHTHIQQAPALH----PQR--- 810
Query: 564 PTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPP-----PMDPSNFVTMMGM 618
PP PP P +P PP P GSAG AP PP P P + +
Sbjct: 811 ------PPSPHPP-PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLL 863
Query: 619 GVAGMP-PFGMPP 630
G P PFG+PP
Sbjct: 864 QHPGPPQPFGLPP 876
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 115 bits (289), Expect = 9e-26
Identities = 124/500 (24%), Positives = 179/500 (35%), Gaps = 58/500 (11%)
Query: 178 RGKGSVKEGKVGRK------DGQMLP--------GEDEPLHALVTANTM--ENVKKAVEQ 221
R +GS+ + GRK DG+ P G + P A ++N E VKK+ ++
Sbjct: 576 RSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKK 635
Query: 222 IRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTK 281
++ +++ + Q + E R + + I RP SE ++ +
Sbjct: 636 VKEEASSPLKSNKRQREKVASDTEEADRTSSK-KTKTQEISRPNSPSEGEGESSDSRSVN 694
Query: 282 CGGAGH---IASDCKFQRPGDPQSAQDKARMD----KEYLSLMAELGEAPVPASVGSTSG 334
G+ I D + P P +++ D ++ L +AP + +S
Sbjct: 695 DEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSA 754
Query: 335 PATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH------GMHGGGPG 388
P TP P P A PP S T S+ P P+ P+ +H P
Sbjct: 755 PPGTPQLPTPGPTPSATAVPPQG--SPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPP 812
Query: 389 GPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPP------PMNQGPHPPGHH 442
P PH PHP G G P + PP PP P P+ Q P PP
Sbjct: 813 SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPF 872
Query: 443 GPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMP--------PPPPPPSGQP--PPP 492
G PP G P+G+ + + P + P PP P P PP
Sbjct: 873 GLPPQASQ-GQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP 931
Query: 493 PSGPLPPWQQQQQQPPPP----PPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQ-- 546
P+ P+P Q PP P P S A+ P P + ++ +T + PP Q
Sbjct: 932 PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 991
Query: 547 -QQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPP 605
Q +SP P +P PP PP G P PP + PPP P
Sbjct: 992 PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT--GLHQVAPQPPFAQHPFVPGGPPPITP 1049
Query: 606 PMDPSNFVTMMGMGVAGMPP 625
P PS G G + PP
Sbjct: 1050 PTCPSTSTPPAGPGTSAQPP 1069
Score = 57.0 bits (136), Expect = 5e-08
Identities = 58/193 (30%), Positives = 70/193 (36%), Gaps = 38/193 (19%)
Query: 444 PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQ 503
P P D S S ++ Q + P G+ P P P G P P GP P
Sbjct: 716 PSPQDNESDSD--SSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTP----S 769
Query: 504 QQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGN 563
PP P++S A + P A T +P QQA A PQ
Sbjct: 770 ATAVPPQGSPTASQAPNQP------------QAPTAPVPHTHIQQAPALH----PQR--- 810
Query: 564 PTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPP-----PMDPSNFVTMMGM 618
PP PP P +P PP P GSAG AP PP P P + +
Sbjct: 811 ------PPSPHPP-PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLL 863
Query: 619 GVAGMP-PFGMPP 630
G P PFG+PP
Sbjct: 864 QHPGPPQPFGLPP 876
>gi|42544127 splicing factor 1 isoform 4 [Homo sapiens]
Length = 80
Score = 112 bits (281), Expect = 8e-25
Identities = 56/68 (82%), Positives = 59/68 (86%), Gaps = 6/68 (8%)
Query: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYI------V 54
MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYI +
Sbjct: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIGKYTFCI 60
Query: 55 QLQIEDLT 62
Q+ E +T
Sbjct: 61 QMHFEIVT 68
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 112 bits (279), Expect = 1e-24
Identities = 110/369 (29%), Positives = 135/369 (36%), Gaps = 77/369 (20%)
Query: 327 ASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGG 386
AS+ S S PA+TP S P A + PP S + + P S P P +
Sbjct: 439 ASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL--SSPLTIHPLQALSSLA 496
Query: 387 PGGPGG----------------GPHSFPHPLPSLTGGHGGHPMQHNPN-GPPP------- 422
P P S P SLT P+++ P+ PPP
Sbjct: 497 SHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLT----TPPLENLPSLAPPPLQTASAP 552
Query: 423 ---PWMQPPPPPMN---QGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMG 476
P ++ PP P Q P P PP + + P Q + PP+
Sbjct: 553 LTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP--------PQAPPALASPPLQ 604
Query: 477 MMPPPPPPPSGQPPP--PPSGPLPPWQQQQQQPPPPP--PPSSSMASSTPLPWQQNTTTT 532
+P PP P PPP PP LPP Q PP PP PP S +A TP P N
Sbjct: 605 GLPSPPLSPLATPPPQAPPXLALPP----LQAPPSPPASPPLSPLA--TPSPQAPNALAV 658
Query: 533 TTSAGTGSIPPWQQQQA-------------AAAASPGAPQMQGNPTMVPLPPGVQPPLPP 579
S PP QA A S P + P VP P PP+ P
Sbjct: 659 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 718
Query: 580 GAPPPPPPPPPGSAGMMYAPP-PPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPP----- 633
A PPP PPP +A + PP PP PPM PS + PP +PP+PP
Sbjct: 719 SATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPM 778
Query: 634 ----PPPPQ 638
PPPQ
Sbjct: 779 SPLAKPPPQ 787
Score = 103 bits (256), Expect = 6e-22
Identities = 98/352 (27%), Positives = 123/352 (34%), Gaps = 45/352 (12%)
Query: 326 PASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGG 385
P + + S P TTP P AP PPS ++T P + P P
Sbjct: 543 PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP 602
Query: 386 GPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHH--- 442
G P P P P+Q P+ P P + P P Q P+ H
Sbjct: 603 LQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 662
Query: 443 ---GPPPMDQYLG------STPVGSGVYRLHQGKGMMPPPPMGMMPPPP--PPPSGQPPP 491
PPP S PV Q + PP+ + P PP PP S P
Sbjct: 663 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 722
Query: 492 PPSGPLPPWQQQQQQPPPPPPPSSSMA-SSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAA 550
PP P PP Q PP PP S M+ S+TP P S P
Sbjct: 723 PPQAP-PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPL 781
Query: 551 AAASPGAPQMQGNPTMVPLP------PGVQP-------PLPPGAPPPPPPPPPGSAGMMY 597
A P AP P + LP PG P P+ P A PPP PP +A ++
Sbjct: 782 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 841
Query: 598 APPPPP----------PPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPPPQN 639
PP PP PP P V+ + +A + P PPPPP ++
Sbjct: 842 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA------LAPGPPPPPSRS 887
Score = 92.0 bits (227), Expect = 1e-18
Identities = 97/338 (28%), Positives = 129/338 (38%), Gaps = 63/338 (18%)
Query: 326 PASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGG 385
P+S+ + A LAS P P+ PP L + PP + P ++ P
Sbjct: 584 PSSIATPPPQAPPALASPPLQGLPS--PPLSPLATPPPQAPPXLALPPLQAPP------S 635
Query: 386 GPGGPGGGPHSFPHP-LPSLTGGHGGHPMQHNPNGPPP------PWMQPPPPPMNQGPHP 438
P P P + P P P+ H + P PPP P+ P PP++ P
Sbjct: 636 PPASPPLSPLATPSPQAPNALAVH----LLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 691
Query: 439 PGHHGP----PPMD---QYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPP--PP--PSG 487
P P PP+ S P+ Q + PP+ + P PP PP PS
Sbjct: 692 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSA 751
Query: 488 QPPP--PPSGPLPPWQQQQQQPPPP----------PPPSSSMASSTPLPWQQNTTTTTTS 535
PPP PP PP Q P PP PPP + A +TP P Q + +
Sbjct: 752 TPPPRVPPLLAAPPLQVP---PSPPASLPMSPLAKPPPQAPPALATP-PLQALPSPPASF 807
Query: 536 AGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAP-------PPPPPP 588
G P A+ SP A P ++ P PP PP +P PP P P
Sbjct: 808 PGQAPFSP----SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 863
Query: 589 PPGSAG----MMYAPPPPPPPPMDPSNFVTMMGMGVAG 622
+G + AP PPPPP PS+ T+ G +AG
Sbjct: 864 DTSVSGPRLTLALAPGPPPPPSRSPSS--TLSGPDLAG 899
Score = 77.0 bits (188), Expect = 5e-14
Identities = 86/307 (28%), Positives = 112/307 (36%), Gaps = 46/307 (14%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSG-------PSES 376
PV A + P +P A+ P A P+ PP + + + PP S P +
Sbjct: 672 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 731
Query: 377 RPYHGMHGGGPGGPGGGPHSFPHP-LPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQG 435
P + P P P + P P +P L P+Q P+ PP P P
Sbjct: 732 APPLQVPPSPPASPPMSPSATPPPRVPPLLAAP---PLQVPPS---PPASLPMSPLAKPP 785
Query: 436 PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQP--PPPP 493
P P PP+ Q L S P +P P+ PP PP P PP
Sbjct: 786 PQAPPALATPPL-QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 844
Query: 494 SGPLPPWQQQQQQPP--------------------PPPPPSSSMAS--STPLPWQQNTTT 531
S P P Q ++PP PPPPPS S +S S P +++
Sbjct: 845 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 904
Query: 532 TTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPL----PPGAPPP-PP 586
T+T + AAA+ P A +P P PPL PGAP P PP
Sbjct: 905 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA--PPLAFRGAPGAPLPWPP 962
Query: 587 PPPPGSA 593
PGSA
Sbjct: 963 ATGPGSA 969
Score = 63.9 bits (154), Expect = 4e-10
Identities = 86/342 (25%), Positives = 112/342 (32%), Gaps = 54/342 (15%)
Query: 322 EAPVPASVGSTSGPATTPLASAPR----PAAPANNPPPPSLMSTTQSRPPWMNSGPSESR 377
+ P S+ S++ P ++P S P P APA+ P P RPP + ++
Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAH-PSQPKPKGLQALRPPQVTPPRKDAA 293
Query: 378 PYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPH 437
P G P P PS T P N P P + P PP P
Sbjct: 294 PALGPLSSSP---------LATPSPSGTKARPVPPPD-NAATPLPATLPPSPPLATPLPL 343
Query: 438 PPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPP---PPMGMMPPPPPPPSGQPPPPPS 494
P PP Q L S P PP PP PP PPS Q PP
Sbjct: 344 APPSPSAPPSLQTLPSPPA-------------TPPSQAPPSMTTPPMQAPPSLQTIPPIQ 390
Query: 495 GPLPPWQQQQQQPPPPPPPSSSMAS-STPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAA 553
P Q PP P SS A+ S P Q T + T + P Q + +
Sbjct: 391 VPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMS-----PRQTQASLTSPS 445
Query: 554 SPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPP-------PPPGSAGMMYAPPPPPP-- 604
P + P PL PPL P P P + + + P P
Sbjct: 446 RPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS 505
Query: 605 ----PPMDPSNFVTMMGM----GVAGMPPFGMPPAPPPPPPQ 638
PP++ + + + PP P+ PPP Q
Sbjct: 506 SLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQ 547
Score = 58.9 bits (141), Expect = 1e-08
Identities = 88/371 (23%), Positives = 122/371 (32%), Gaps = 85/371 (22%)
Query: 336 ATTPLASAP---RPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGG 392
A TP A AP P P + PPP + T + + + + R GG GG
Sbjct: 14 ARTPAARAPGLLTPRPPGSPRPPPPV---TPAALRVLGAAGAVGRKPLAERAGGIGG-AT 69
Query: 393 GPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWM--QPPPPPMNQGPHP---PGHHGPPPM 447
P S P P+ + G NP PP + PP N P P PG
Sbjct: 70 IPESAPRAGPTRSAGTSSR----NPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125
Query: 448 DQYLGSTPVG-SGVYRLHQGKGMMPP---------------PPMGMMPP----------- 480
LG + S + +GK P P G P
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 185
Query: 481 ----PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSA 536
P P PS +P PP GP + P P++ S Q+ + + +S+
Sbjct: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 537 GTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPP------------ 584
T P + ++ G P+ +P+ P P G+Q PP PP
Sbjct: 246 AT----PLSSPARSGPSARGTPRAPAHPSQ-PKPKGLQALRPPQVTPPRKDAAPALGPLS 300
Query: 585 ---------------PPPPPPGSAGMMYA--PPPPP---PPPMDPSNFVTMMGMGVAGMP 624
P PPP +A + A PP PP P P+ P + + P
Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360
Query: 625 PFGMPPAPPPP 635
P PP+ PP
Sbjct: 361 P-ATPPSQAPP 370
Score = 56.6 bits (135), Expect = 7e-08
Identities = 71/308 (23%), Positives = 101/308 (32%), Gaps = 42/308 (13%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPAN-NPPPPSLMSTTQSRPPWMNSGPSESRPYHGM 382
P PA + T PRPA A PP + S + PS +
Sbjct: 172 PSPAMARRSRAAGTE--VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPS 229
Query: 383 HGGG---PGGPGGGPHSFPHPLPSLTG--GHGGHPMQHNPNGPPPPWMQPPPPPMNQGPH 437
GGG P + P P+ +G G +P+ P P +Q PP P
Sbjct: 230 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 289
Query: 438 PPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPP-------------------PMGMM 478
P+ +TP SG +PPP P+ +
Sbjct: 290 KDAAPALGPLSSSPLATPSPSGTKARP-----VPPPDNAATPLPATLPPSPPLATPLPLA 344
Query: 479 PP-PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAG 537
PP P PPS Q P P PP Q PP S+ + P+ + T+ + A
Sbjct: 345 PPSPSAPPSLQTLPSPPA-TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP 403
Query: 538 TGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPP-----GVQPPLPPGAPPPPPPPPPGS 592
P A S G+P +Q + + + P + P P + PP PP
Sbjct: 404 PS---PLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAP 460
Query: 593 AGMMYAPP 600
+ +PP
Sbjct: 461 LSLPASPP 468
Score = 53.5 bits (127), Expect = 6e-07
Identities = 92/390 (23%), Positives = 124/390 (31%), Gaps = 67/390 (17%)
Query: 297 PGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSG---PATTPLASAPRPAAPANNP 353
PG P+ L +G P+ G G P + P A R A ++
Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRN 89
Query: 354 PP--PSLMSTTQSRPPWMNSGP---SESRPYHGMHGGGPGGPGG-----------GPHSF 397
P P + PP N+ P S G GP G G G +
Sbjct: 90 PASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 149
Query: 398 PHPLPSLTGGHGGHPMQHNPNGPPPPWMQP----------PPPPMNQGPHPPGHHGP--- 444
+L+ G P P P + P P + P PP GP
Sbjct: 150 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE-GPRKS 208
Query: 445 -PPMDQYLGSTPVGSGVYRLHQGKGMMPPP---------PMGMMPPPPPPPSGQPPPP-- 492
++ + P + R G G+ P P+ P G P P
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268
Query: 493 PSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAA 552
PS P P Q + P PP + + PL T + + +PP
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLP 328
Query: 553 AS-PGAPQMQGNPTMVPLPPGVQPPLPPGAPP-----PPPPPPPGSAGMMYAPPPPPPPP 606
A+ P +P P PLP + PP P APP P PP P S APP PP
Sbjct: 329 ATLPPSP-----PLATPLP--LAPP-SPSAPPSLQTLPSPPATPPS----QAPPSMTTPP 376
Query: 607 MD-PSNFVTMMGMGV---AGMPPFGMPPAP 632
M P + T+ + V P PP+P
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406
Score = 48.5 bits (114), Expect = 2e-05
Identities = 70/299 (23%), Positives = 88/299 (29%), Gaps = 93/299 (31%)
Query: 323 APVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGM 382
A P S +T P PL +AP P + PP SL + ++PP + P +
Sbjct: 743 ASPPMSPSATPPPRVPPLLAAPPLQVPPS--PPASLPMSPLAKPPPQAPPALATPPLQAL 800
Query: 383 HGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPP----PWMQ-PPPPPMN---Q 434
PG P S LP P+ P PP P +Q PP PP + Q
Sbjct: 801 PSPPASFPGQAPFSPSASLPM-------SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 853
Query: 435 GPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPP---- 490
P P GP T V P + + P PPPPPS P
Sbjct: 854 APRRPPTPGP--------DTSVSG------------PRLTLALAPGPPPPPSRSPSSTLS 893
Query: 491 --------------------------------PPPSGPLPPWQQQQQQPPPPPPPSSSMA 518
PPP L P PP + A
Sbjct: 894 GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA 953
Query: 519 SSTPLPWQ--------------------QNTTTTTTSAGTGSIPPWQQQQAAAAASPGA 557
PLPW ++ T + G P +AAA A GA
Sbjct: 954 PGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGA 1012
Score = 34.3 bits (77), Expect = 0.36
Identities = 27/92 (29%), Positives = 34/92 (36%), Gaps = 28/92 (30%)
Query: 571 PGVQPPLPPGAPPPPPPPPP------GSAGMMYAPP-------------PPPPPPMDPSN 611
PG+ P PPG+P PPPP P G+AG + P P P P+
Sbjct: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81
Query: 612 FVTMMGMGVAGMPPFGMPPA----PPPPPPQN 639
G + P PPA PP +N
Sbjct: 82 -----SAGTSSRNPASRPPASGRGERAPPAKN 108
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 108 bits (269), Expect = 2e-23
Identities = 89/263 (33%), Positives = 99/263 (37%), Gaps = 68/263 (25%)
Query: 381 GMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNP--NGPPPPWMQPPPPPMNQGPHP 438
G H G GG GG H F P P + PM P +GP PP PPPPP Q P
Sbjct: 15 GFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPI--PPPPPHQQQQQP 72
Query: 439 PGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLP 498
P PPP PP QPPP P
Sbjct: 73 P------------------------------------PQQPPPQQPPPHQPPPHPQ---- 92
Query: 499 PWQQQQQQPPPPPPPSSS-MASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGA 557
P QQ QQPPPPP SS + + P P + G GS PP A+++A P
Sbjct: 93 PHQQ--QQPPPPPQDSSKPVVAQGPGP----------APGVGSAPP-----ASSSAPPAT 135
Query: 558 PQMQGNPT-MVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPP----PPPPPPMDPS-N 611
P G P P P PP APP PPP P S+G+ PP PPPPP P
Sbjct: 136 PPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPG 195
Query: 612 FVTMMGMGVAGMPPFGMPPAPPP 634
G G G MP P P
Sbjct: 196 PGPKQGPGPGGPKGGKMPGGPKP 218
Score = 79.0 bits (193), Expect = 1e-14
Identities = 66/190 (34%), Positives = 70/190 (36%), Gaps = 46/190 (24%)
Query: 457 GSGVYRLHQGKGMMPPPPMGMMPPPPP--PPSGQPPPPPSGPLPPWQQQQQQPPPPPPPS 514
G G LH + PPP MG+ P P GQ P P P PP QQQQQPPP PP
Sbjct: 22 GGGRGGLHDFRS--PPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPP 79
Query: 515 SSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLP---P 571
P P Q P QQQQ P PQ P + P P
Sbjct: 80 QQPPPHQPPPHPQ---------------PHQQQQP-----PPPPQDSSKPVVAQGPGPAP 119
Query: 572 GV--QPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMP 629
GV PP APP PP G P P PPP V PP
Sbjct: 120 GVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPP-------------AVTSAPP---- 162
Query: 630 PAPPPPPPQN 639
APPP PP +
Sbjct: 163 GAPPPTPPSS 172
Score = 66.2 bits (160), Expect = 9e-11
Identities = 58/190 (30%), Positives = 67/190 (35%), Gaps = 29/190 (15%)
Query: 344 PRPAAPANNPPPPSLMST------------TQSRPPWMNSGPSESRPYHGMHGGGPGGPG 391
P+P PPPP S S PP +S P + P G PG
Sbjct: 91 PQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSG------APPG 144
Query: 392 GGPHSFPHPLPSLTGGHGGHPMQHNPNG-----PPPPWMQPPPPPMNQGPHPPGHHGPPP 446
GP P P P++T G P P+ PP PPPP GP P GP P
Sbjct: 145 SGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGP 204
Query: 447 MDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQ 506
G P G + G G+ P G P PP G+P P QQ Q
Sbjct: 205 GGPKGGKMPGGP---KPGGGPGLSTP---GGHPKPPHRGGGEPRGGRQHHPPYHQQHHQG 258
Query: 507 PPPPPPPSSS 516
PPP P S
Sbjct: 259 PPPGGPGGRS 268
Score = 64.7 bits (156), Expect = 2e-10
Identities = 64/216 (29%), Positives = 72/216 (33%), Gaps = 36/216 (16%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMH 383
P+P P P+ P PP P Q PP +S S+P
Sbjct: 59 PIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDS----SKPVVAQG 114
Query: 384 GGGPGGPGGGP---HSFPHPLPSLTGGHGGHPMQHNPNGPP-----PPWMQPPPPPMNQG 435
G G G P S P P +G G P PP PP PP PP +
Sbjct: 115 PGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGV 174
Query: 436 P-HPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPP--------PS 486
P PP GPPP + G QG G P G MP P P P
Sbjct: 175 PTTPPQAGGPPPPPAAVPGPGPGP-----KQGPG-PGGPKGGKMPGGPKPGGGPGLSTPG 228
Query: 487 GQPPPPPSG---------PLPPWQQQQQQPPPPPPP 513
G P PP G PP+ QQ Q PPP P
Sbjct: 229 GHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGP 264
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 107 bits (267), Expect = 3e-23
Identities = 101/305 (33%), Positives = 107/305 (35%), Gaps = 66/305 (21%)
Query: 349 PANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGH 408
P PPPP + RPP S+ P GP GG P P P G
Sbjct: 47 PQRTPPPPG---KPEGRPP-QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQ 102
Query: 409 ---GGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQ 465
GG+ Q P P P PPP NQ PP G P G P G +Q
Sbjct: 103 PPQGGNQSQGPPPRPGKP-EGPPPQGGNQSQGPPPRPGKPE-----GPPPQGG-----NQ 151
Query: 466 GKGMMPPPPMGMMPPPPPPPSG---QPPPP----PSGPLPPWQQQQQQPPPPP------P 512
+G PPP P PPP G Q PPP P GP P Q Q PPP P P
Sbjct: 152 SQG---PPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPP 208
Query: 513 PSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASP------GAPQMQGNPTM 566
P S P P G PP Q P G P +GN
Sbjct: 209 PQGGNQSQGPPP----------RPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQ 258
Query: 567 VPLPPG-VQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPP 625
P PPG Q P PPG P P PPP AG PPPPP G PP
Sbjct: 259 RPPPPGRPQGPPPPGGNPQQPLPPP--AGKPQGPPPPPQG-------------GRPHRPP 303
Query: 626 FGMPP 630
G PP
Sbjct: 304 QGQPP 308
Score = 104 bits (259), Expect = 3e-22
Identities = 104/323 (32%), Positives = 117/323 (36%), Gaps = 56/323 (17%)
Query: 336 ATTPLASAPRPAAPANNPPPPSLMS-TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGP 394
A L+SA + PS++S + R P + P + P G G P GG
Sbjct: 9 ALLALSSAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPP-QGGNQ 67
Query: 395 HSFPHPLPSLTGG---HGGHPMQHNPNGPPPPWMQPPPPP-MNQGPHP-PGH-HGPPPM- 447
P P P G GG+ Q P P P QPP +QGP P PG GPPP
Sbjct: 68 SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQG 127
Query: 448 -DQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQ 506
+Q G P GK PPP G PPP G+P PP P Q Q
Sbjct: 128 GNQSQGPPP--------RPGKPEGPPPQGGNQSQGPPPRPGKPEGPP----PQGGNQSQG 175
Query: 507 PPPPP------PPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQM 560
PPP P PP S P P G PP Q S G P
Sbjct: 176 PPPHPGKPEGPPPQGGNQSQGPPP----------RPGKPEGPPPQ----GGNQSQGPPPR 221
Query: 561 QGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPP-----PPPPMDPSNFVTM 615
G P P G +P PP P P PPP PPPP PPPP
Sbjct: 222 PGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPG-------- 273
Query: 616 MGMGVAGMPPFGMPPAPPPPPPQ 638
G +PP P PPPPPQ
Sbjct: 274 -GNPQQPLPPPAGKPQGPPPPPQ 295
Score = 97.4 bits (241), Expect = 3e-20
Identities = 88/282 (31%), Positives = 98/282 (34%), Gaps = 66/282 (23%)
Query: 344 PRPAAPANNPP--------PPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPH 395
PRP P PP PP + +PP S+ P GP GG
Sbjct: 73 PRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPP-QGGNQSQGPPPRPGKPEGPPPQGGNQS 131
Query: 396 SFPHPLPSLTGG---HGGHPMQHNPNGPPP-PWMQPPPPPM--NQGPHPPGHHGPPPMDQ 449
P P P G GG+ Q GPPP P PPP NQ PP H G P
Sbjct: 132 QGPPPRPGKPEGPPPQGGNQSQ----GPPPRPGKPEGPPPQGGNQSQGPPPHPGKPE--- 184
Query: 450 YLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQ----PPPPPSGPLPPWQQQQQ 505
G P G +Q +G PPP P PPP G PPP P P P Q
Sbjct: 185 --GPPPQGG-----NQSQG---PPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGN 234
Query: 506 QPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPT 565
+P PPP PP + + PG PQ
Sbjct: 235 KPQGPPPHPGKPQGP---------------------PPQEGNKPQRPPPPGRPQ------ 267
Query: 566 MVPLPPGVQP--PLPPGAPPPPPPPPPGSAGMMYAPPPPPPP 605
P PPG P PLPP A P PPPP G + PP PP
Sbjct: 268 -GPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPP 308
Score = 91.7 bits (226), Expect = 2e-18
Identities = 80/246 (32%), Positives = 85/246 (34%), Gaps = 40/246 (16%)
Query: 410 GHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHH---GPPPMDQYLGSTPVGSGVYRLHQG 466
G P P G P PPPP +G P G + GPPP P G +Q
Sbjct: 34 GKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGG----NQS 89
Query: 467 KGMMPPPPMGMMPPPPPPPSG---QPPPP----PSGPLPPWQQQQQQPPPPP------PP 513
+G PPP P PP G Q PPP P GP P Q Q PPP P PP
Sbjct: 90 QG---PPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPP 146
Query: 514 SSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGV 573
S P P G PP Q S G P G P P G
Sbjct: 147 QGGNQSQGPPP----------RPGKPEGPPPQ----GGNQSQGPPPHPGKPEGPPPQGGN 192
Query: 574 QPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPP 633
Q PP P P PPP PPP P P P + G G PP P P
Sbjct: 193 QSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPS---QGGNKPQGPPPHPGKPQGP 249
Query: 634 PPPPQN 639
PP N
Sbjct: 250 PPQEGN 255
Score = 84.0 bits (206), Expect = 4e-16
Identities = 78/228 (34%), Positives = 86/228 (37%), Gaps = 50/228 (21%)
Query: 322 EAPVPASVGSTSGPATTPLASAPRPAAPANNPP--------PPSLMSTTQSRPPWMNSGP 373
E P P + GP PRP P PP PP + PP
Sbjct: 79 EGPPPQGGNQSQGPP-------PRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPP-QGGNQ 130
Query: 374 SESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGG---HGGHPMQHNPNGPPP-PWMQPPP 429
S+ P GP GG P P P G GG+ Q GPPP P P
Sbjct: 131 SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQ----GPPPHPGKPEGP 186
Query: 430 PP----MNQGPHP-PGH-HGPPPM--DQYLG--------STPVGSGVYR-----LHQGKG 468
PP +QGP P PG GPPP +Q G P G + H GK
Sbjct: 187 PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKP 246
Query: 469 MMPPPPMGMMPPPPPPPS-GQPPPPPSG----PLPPWQQQQQQPPPPP 511
PPP G P PPPP Q PPPP G PLPP + Q PPPPP
Sbjct: 247 QGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPP 294
Score = 83.2 bits (204), Expect = 7e-16
Identities = 71/239 (29%), Positives = 84/239 (35%), Gaps = 46/239 (19%)
Query: 296 RPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPP- 354
RPG P+ + + E P P + GP PRP P PP
Sbjct: 95 RPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPP-------PRPGKPEGPPPQ 147
Query: 355 -------PPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGG 407
PP + PP S+ P H GP GG P P P G
Sbjct: 148 GGNQSQGPPPRPGKPEGPPP-QGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEG 206
Query: 408 ---HGGHPMQHNPNGPPPPWMQPPPPPMNQG-------PHPPGHHGPPPMDQYLGSTPVG 457
GG+ Q GPPP +P PP G PHP GPPP + P
Sbjct: 207 PPPQGGNQSQ----GPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPP 262
Query: 458 SGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQ---PPPPPSGPLPPWQQQQQQPPPPPPP 513
G + PPPP G P PPP+G+ PPPPP G P +PP PP
Sbjct: 263 PG-------RPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRP------HRPPQGQPP 308
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 105 bits (263), Expect = 1e-22
Identities = 72/192 (37%), Positives = 84/192 (43%), Gaps = 48/192 (25%)
Query: 471 PPPPM----GMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQ 526
P PP+ G + PPPP P PPP P PP PPPP P ++S LP
Sbjct: 575 PAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPP-------PPPPLPGGVCISSPPSLPGG 627
Query: 527 QNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAP---- 582
+ +G +IPP P P+ G P+ LP G P PP P
Sbjct: 628 TAISPPPPLSGDATIPP----------PPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSAR 677
Query: 583 -PPPPPPPPGSAGMMYAPPP-------PPPPPMDPSNFVTMMGMGVAGMPPF----GMPP 630
PPPPPP PGSAG+ PPP PPPPP P G G+ PPF G+PP
Sbjct: 678 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPG------GPGIPPPPPFPGGPGIPP 731
Query: 631 AP-----PPPPP 637
P PPPPP
Sbjct: 732 PPPGMGMPPPPP 743
Score = 101 bits (251), Expect = 2e-21
Identities = 78/219 (35%), Positives = 97/219 (44%), Gaps = 38/219 (17%)
Query: 428 PPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM---GMMPPPPPP 484
PP ++ P PP PP+ P SG ++PPPP PPPPPP
Sbjct: 564 PPSVPSRAPVPPA----PPL-------PGDSGT--------IIPPPPAPGDSTTPPPPPP 604
Query: 485 PSGQPPPPPSGPL---PPWQQQQQQPPPPPPPS--SSMASSTPLPWQQNTTTTTTSAGTG 539
P PPP P G PP PPPP S +++ PLP + ++ G
Sbjct: 605 PPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGT 664
Query: 540 SIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPP-PGSAGMMYA 598
+IPP +A P P + G+ + P PP PLP A PPPPPP PG G+
Sbjct: 665 AIPPPPPLPGSARIPPPPPPLPGSAGIPPPPP----PLPGEAGMPPPPPPLPGGPGI--- 717
Query: 599 PPPPPPPPMDPSNFVTMMGMGVAGMPP--FGMPPAPPPP 635
PPPPP P P GMG+ PP FG+P AP P
Sbjct: 718 -PPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLP 755
Score = 88.6 bits (218), Expect = 2e-17
Identities = 102/342 (29%), Positives = 122/342 (35%), Gaps = 127/342 (37%)
Query: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANN----PPPP 356
Q + A++ KE E+ A S P+ P+ P P P ++ PPPP
Sbjct: 534 QLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVP--PAPPLPGDSGTIIPPPP 591
Query: 357 SLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHN 416
+ +T PP P P P PGG S P PSL GG
Sbjct: 592 APGDSTTPPPP-----PPPPPP-------PPPLPGGVCISSP---PSLPGGTA------- 629
Query: 417 PNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM- 475
+ PPPP PP PPP+ + +G S L G + PPPP+
Sbjct: 630 --------ISPPPPLSGDATIPP----PPPLPEGVGIPSPSS----LPGGTAIPPPPPLP 673
Query: 476 --GMMPPPPPP---PSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTT 530
+PPPPPP +G PPPPP PLP + PPPPP PLP
Sbjct: 674 GSARIPPPPPPLPGSAGIPPPPP--PLP---GEAGMPPPPP----------PLP------ 712
Query: 531 TTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPP 590
PG P PP PP P G P PPPPP
Sbjct: 713 ----------------------GGPGIP-----------PP---PPFPGG--PGIPPPPP 734
Query: 591 GSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMP--PFGMPP 630
G M PPPPP G GV P PFG+ P
Sbjct: 735 G----MGMPPPPP------------FGFGVPAAPVLPFGLTP 760
Score = 75.9 bits (185), Expect = 1e-13
Identities = 60/178 (33%), Positives = 69/178 (38%), Gaps = 43/178 (24%)
Query: 497 LPPWQQQQQQPPPPPP-PSSSMASSTPLPWQQNTTT-----------------------T 532
+PP + PP PP P S P P ++TT
Sbjct: 563 VPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPP 622
Query: 533 TTSAGTG-SIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAP-----PPPP 586
+ GT S PP A P P+ G P+ LP G P PP P PPPP
Sbjct: 623 SLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 682
Query: 587 PPPPGSAGMMYAPPP-------PPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPPP 637
PP PGSAG+ PPP PPPPP P G G+ PPF P PPPPP
Sbjct: 683 PPLPGSAGIPPPPPPLPGEAGMPPPPPPLPG------GPGIPPPPPFPGGPGIPPPPP 734
Score = 62.8 bits (151), Expect = 9e-10
Identities = 44/128 (34%), Positives = 51/128 (39%), Gaps = 25/128 (19%)
Query: 535 SAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPP-PGS- 592
SA ++PP +A +P P G P PG PP PPPPPPPP PG
Sbjct: 557 SAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGV 616
Query: 593 ---------AGMMYAPPP--------PPPPPMD-----PSNFVTMMGMGVAGMPPF-GMP 629
G +PPP PPPPP+ PS G + PP G
Sbjct: 617 CISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSA 676
Query: 630 PAPPPPPP 637
PPPPPP
Sbjct: 677 RIPPPPPP 684
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 105 bits (263), Expect = 1e-22
Identities = 72/192 (37%), Positives = 84/192 (43%), Gaps = 48/192 (25%)
Query: 471 PPPPM----GMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQ 526
P PP+ G + PPPP P PPP P PP PPPP P ++S LP
Sbjct: 584 PAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPP-------PPPPLPGGVCISSPPSLPGG 636
Query: 527 QNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAP---- 582
+ +G +IPP P P+ G P+ LP G P PP P
Sbjct: 637 TAISPPPPLSGDATIPP----------PPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSAR 686
Query: 583 -PPPPPPPPGSAGMMYAPPP-------PPPPPMDPSNFVTMMGMGVAGMPPF----GMPP 630
PPPPPP PGSAG+ PPP PPPPP P G G+ PPF G+PP
Sbjct: 687 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPG------GPGIPPPPPFPGGPGIPP 740
Query: 631 AP-----PPPPP 637
P PPPPP
Sbjct: 741 PPPGMGMPPPPP 752
Score = 101 bits (251), Expect = 2e-21
Identities = 78/219 (35%), Positives = 97/219 (44%), Gaps = 38/219 (17%)
Query: 428 PPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM---GMMPPPPPP 484
PP ++ P PP PP+ P SG ++PPPP PPPPPP
Sbjct: 573 PPSVPSRAPVPPA----PPL-------PGDSGT--------IIPPPPAPGDSTTPPPPPP 613
Query: 485 PSGQPPPPPSGPL---PPWQQQQQQPPPPPPPS--SSMASSTPLPWQQNTTTTTTSAGTG 539
P PPP P G PP PPPP S +++ PLP + ++ G
Sbjct: 614 PPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGT 673
Query: 540 SIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPP-PGSAGMMYA 598
+IPP +A P P + G+ + P PP PLP A PPPPPP PG G+
Sbjct: 674 AIPPPPPLPGSARIPPPPPPLPGSAGIPPPPP----PLPGEAGMPPPPPPLPGGPGI--- 726
Query: 599 PPPPPPPPMDPSNFVTMMGMGVAGMPP--FGMPPAPPPP 635
PPPPP P P GMG+ PP FG+P AP P
Sbjct: 727 -PPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLP 764
Score = 88.6 bits (218), Expect = 2e-17
Identities = 102/342 (29%), Positives = 122/342 (35%), Gaps = 127/342 (37%)
Query: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANN----PPPP 356
Q + A++ KE E+ A S P+ P+ P P P ++ PPPP
Sbjct: 543 QLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVP--PAPPLPGDSGTIIPPPP 600
Query: 357 SLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHN 416
+ +T PP P P P PGG S P PSL GG
Sbjct: 601 APGDSTTPPPP-----PPPPPP-------PPPLPGGVCISSP---PSLPGGTA------- 638
Query: 417 PNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM- 475
+ PPPP PP PPP+ + +G S L G + PPPP+
Sbjct: 639 --------ISPPPPLSGDATIPP----PPPLPEGVGIPSPSS----LPGGTAIPPPPPLP 682
Query: 476 --GMMPPPPPP---PSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTT 530
+PPPPPP +G PPPPP PLP + PPPPP PLP
Sbjct: 683 GSARIPPPPPPLPGSAGIPPPPP--PLP---GEAGMPPPPP----------PLP------ 721
Query: 531 TTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPP 590
PG P PP PP P G P PPPPP
Sbjct: 722 ----------------------GGPGIP-----------PP---PPFPGG--PGIPPPPP 743
Query: 591 GSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMP--PFGMPP 630
G M PPPPP G GV P PFG+ P
Sbjct: 744 G----MGMPPPPP------------FGFGVPAAPVLPFGLTP 769
Score = 75.9 bits (185), Expect = 1e-13
Identities = 60/178 (33%), Positives = 69/178 (38%), Gaps = 43/178 (24%)
Query: 497 LPPWQQQQQQPPPPPP-PSSSMASSTPLPWQQNTTT-----------------------T 532
+PP + PP PP P S P P ++TT
Sbjct: 572 VPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPP 631
Query: 533 TTSAGTG-SIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAP-----PPPP 586
+ GT S PP A P P+ G P+ LP G P PP P PPPP
Sbjct: 632 SLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 691
Query: 587 PPPPGSAGMMYAPPP-------PPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPPP 637
PP PGSAG+ PPP PPPPP P G G+ PPF P PPPPP
Sbjct: 692 PPLPGSAGIPPPPPPLPGEAGMPPPPPPLPG------GPGIPPPPPFPGGPGIPPPPP 743
Score = 62.8 bits (151), Expect = 9e-10
Identities = 44/128 (34%), Positives = 51/128 (39%), Gaps = 25/128 (19%)
Query: 535 SAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPP-PGS- 592
SA ++PP +A +P P G P PG PP PPPPPPPP PG
Sbjct: 566 SAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGV 625
Query: 593 ---------AGMMYAPPP--------PPPPPMD-----PSNFVTMMGMGVAGMPPF-GMP 629
G +PPP PPPPP+ PS G + PP G
Sbjct: 626 CISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSA 685
Query: 630 PAPPPPPP 637
PPPPPP
Sbjct: 686 RIPPPPPP 693
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 105 bits (261), Expect = 2e-22
Identities = 113/429 (26%), Positives = 153/429 (35%), Gaps = 88/429 (20%)
Query: 285 AGHIASDC-------KFQRPGDPQSAQDKARMD---KEYLSLMAELGEAPVPASVGSTSG 334
AGH+ S + + G KARM+ + Y SL+ L P + + S
Sbjct: 564 AGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQ 623
Query: 335 PATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGP 394
P+ P P P PPPP +QS P + P +
Sbjct: 624 PSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAP-----SAGSAAPMFVKYSTITRLQNASQ 678
Query: 395 HS---FPHPLPSLTGGHGGHP-MQHNPNG--PPPPWMQPPPPPMNQGPHPPGHHGPP--P 446
HS F P P + P + PNG PPPP PPPPP G P P
Sbjct: 679 HSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPP---PPPPPPTPGSAMAQLKPAPCAP 735
Query: 447 MDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPP-----PPSGQP------------ 489
+ P ++++ + PP P PPPPP PP P
Sbjct: 736 SLPQFSAPPPPLKIHQVQHITQVAPPTP----PPPPPIPAPLPPQAPPKPLVTIPAPTST 791
Query: 490 -----------PPPPSGPLPPWQQQQQQPP---PPPPPSSSMASSTP-LPWQQNTTTTTT 534
PP P+ P+PP ++Q P PP PP+ + P LP QQ+
Sbjct: 792 KTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPP 851
Query: 535 SAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPG-------------A 581
+ +P +Q A+ P P + + P+P V P PP
Sbjct: 852 PSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPV 911
Query: 582 PPPPPPPPPGSAGMMYAPPPP-----PPPPMDPSNFVTMMGMGVAG------MPPFGMPP 630
P P PPPP + +++ PPPP PPPP P+ T G G P G
Sbjct: 912 PSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGG--K 969
Query: 631 APPPPPPQN 639
PPP P +N
Sbjct: 970 KPPPTPQRN 978
Score = 74.3 bits (181), Expect = 3e-13
Identities = 97/378 (25%), Positives = 124/378 (32%), Gaps = 75/378 (19%)
Query: 315 SLMAELGEAPVPASVGSTSGPA-------------TTPLASAPRPAAPANNPPP------ 355
S MA+L AP S+ S P P P P PA PP
Sbjct: 723 SAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPL 782
Query: 356 ---PSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGG----GPHSFPHPLPSLTGGH 408
P+ ST P + P P P P P + P P+P T
Sbjct: 783 VTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPT--- 839
Query: 409 GGHPMQHNPNGPPPPWMQPPPPPM-----NQGPHPPGHHGPPPMD-QYLGSTPVGSGVYR 462
P Q + PPP P P + +Q P PP PP M+ Q L P
Sbjct: 840 --LPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPT---PPAMESQPLKPVPANVAPQS 894
Query: 463 LHQGKG---------------MMPPPPMGMM--PPPPPPPSGQPPPPPSGPLPPWQQQQQ 505
K PPPP + PPPPP P PPPPP P +
Sbjct: 895 PPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSG 954
Query: 506 QPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPT 565
P +SS P P Q ++ +S+G P + + + P G+P+
Sbjct: 955 SPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPS 1014
Query: 566 MVPLPPGVQPPLPPGAPPPPPPPPPG--SAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGM 623
LPP PP PG PG G + A P + G G +
Sbjct: 1015 KETLPPPAAPP-KPGKLNLSGVNLPGVLQQGCVSAKAP------------VLSGRGKDSV 1061
Query: 624 PPFGMPPAP---PPPPPQ 638
F PP+ PPPPP+
Sbjct: 1062 VEFPSPPSDSDFPPPPPE 1079
Score = 49.3 bits (116), Expect = 1e-05
Identities = 95/448 (21%), Positives = 117/448 (26%), Gaps = 156/448 (34%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNP-----------PPPSLMSTTQS-------- 364
PVP + + PA+ S P P P P PPPS +S S
Sbjct: 809 PVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQ 868
Query: 365 -----RPPWMNSGPSESRPYHGMHGGGPG---GPGGGPHSFPHPLPSLTGGHGGHPMQHN 416
PP M S P + P + P P P S P P P +
Sbjct: 869 FPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFP 928
Query: 417 PNGPPPPWMQPPPPPMNQGPHP---------------PGHHGPPPMDQYLGSTPVGSGVY 461
P P P PPPPP P P PG PPP Q S SG
Sbjct: 929 PPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAE 988
Query: 462 RLHQ---------------------GKGMMPPPPMGMMP--------------------- 479
K +PPP P
Sbjct: 989 HPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSA 1048
Query: 480 ----------------PPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPL 523
P PP S PPPPP LP PP P+ +++P
Sbjct: 1049 KAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELP--------LPPIEIPAVFSGNTSP- 1099
Query: 524 PWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPP 583
+ W + A P P+ + + QP + P
Sbjct: 1100 ---------KVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQ 1150
Query: 584 PPPPP------PPG--------------------SAGMMYAP----------PPPPPPPM 607
P P PG S+ M A PPPPP +
Sbjct: 1151 VPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELL 1210
Query: 608 DPSNFVTMMGMGVAGMPPF--GMPPAPP 633
G ++G G PPAPP
Sbjct: 1211 SDQQKAGYGGSHISGYATLRRGPPPAPP 1238
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 105 bits (261), Expect = 2e-22
Identities = 95/323 (29%), Positives = 124/323 (38%), Gaps = 68/323 (21%)
Query: 349 PANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPS----L 404
P + P P + QS+P +S PS+ + P P P P PS +
Sbjct: 276 PPSLQPTPQVPQVQQSQPS-QSSEPSQPQQKDPQQPAQQQQPAQQPKK-PSPQPSSPRQV 333
Query: 405 TGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLH 464
P + N PPP P P + HPP PP D+ P+ + +
Sbjct: 334 KRAVVVSPKEENKAAEPPP----PKIPKIETTHPPLPPAHPPPDR---KPPLAAAL---- 382
Query: 465 QGKGMMPPP------PMGMMPPPP-PPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSM 517
G+ P P P +PPP P P QPPP P PPPPPPSS M
Sbjct: 383 -GEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLP------------HRPPPPPPSSYM 429
Query: 518 ASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPL 577
+ TT++ +G G + + P G P +P P V PP
Sbjct: 430 TGMS--------TTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPN 481
Query: 578 PPGAPPPPPPP-------PPGSAGMMYAPP------PPPPPPMDPSNFV---TMMGMGV- 620
PP P PPPP PP + G PP PPPPP + P++ V G+G+
Sbjct: 482 PPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLP 541
Query: 621 ------AGMPPFGMPPAPPPPPP 637
+PP G PP PPP PP
Sbjct: 542 PASYPPPAVPPGGQPPVPPPIPP 564
Score = 83.2 bits (204), Expect = 7e-16
Identities = 82/299 (27%), Positives = 99/299 (33%), Gaps = 66/299 (22%)
Query: 326 PASVGSTSGPATTPLASAPRPAAP----------------ANNPPPPSLMSTTQSRPPWM 369
P PA P +P+P++P A PPPP + + PP
Sbjct: 307 PQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLP 366
Query: 370 NSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPP 429
+ P R G P G + P +Q P P P QPPP
Sbjct: 367 PAHPPPDRKPPLAAALGEAEPPGPVDATDLP-----------KVQIPPPAHPAPVHQPPP 415
Query: 430 PPMNQGPHPPGHH--GPPPMDQYLGSTPVGSGVYRLHQ-------GKGMMPPP--PMGMM 478
P P PP + G Y+ G G L G +PP P +
Sbjct: 416 LPHRPPPPPPSSYMTGMSTTSSYMS----GEGYQSLQSMMKTEGPSYGALPPAYGPPAHL 471
Query: 479 P------PPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTT 532
P PP PPP PPPP S P PP PPPPP+ + P P
Sbjct: 472 PYHPHVYPPNPPPPPVPPPPASFP-PPAIPPPTPGYPPPPPTYNPNFPPPPP-------- 522
Query: 533 TTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPG 591
+PP G P P VP PG QPP+PP PPP PP G
Sbjct: 523 -------RLPPTHAVPPHPPPGLGLPPASYPPPAVP--PGGQPPVPPPIPPPGMPPVGG 572
Score = 78.2 bits (191), Expect = 2e-14
Identities = 77/220 (35%), Positives = 85/220 (38%), Gaps = 55/220 (25%)
Query: 316 LMAELGEAPVPASVGSTSGPATTPLASAPRPAAPAN-----------NPPPPSLMSTTQS 364
L A LGEA P V +T P P PA PA PPPPS T S
Sbjct: 378 LAAALGEAEPPGPVDATD----LPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMS 433
Query: 365 RPPWMNSGPSESRPYHGMHGGGPG----GPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
SG M GP P GP P LP HP + PN P
Sbjct: 434 TTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGP---PAHLPY-------HPHVYPPNPP 483
Query: 421 PPPWMQPPP---PPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPP--PPM 475
PPP + PPP PP P PG+ PPP Y + P PP PP
Sbjct: 484 PPP-VPPPPASFPPPAIPPPTPGY--PPPPPTYNPNFPPP-------------PPRLPPT 527
Query: 476 GMMPPPPPPPSGQPP---PPPSGPLPPWQQQQQQPPPPPP 512
+PP PPP G PP PPP+ +PP Q PP PPP
Sbjct: 528 HAVPPHPPPGLGLPPASYPPPA--VPPGGQPPVPPPIPPP 565
Score = 65.9 bits (159), Expect = 1e-10
Identities = 64/232 (27%), Positives = 81/232 (34%), Gaps = 66/232 (28%)
Query: 465 QGKGMMP-------PPPMGMMPPPPPPPSGQPPPPPSG-PLPPWQQQQQQPPPPPPPSSS 516
QGK MP P + P P P Q P S P P Q+ QQP P+
Sbjct: 260 QGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQ 319
Query: 517 MASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPP 576
+P P + P ++ +AA P P+++ T PLPP PP
Sbjct: 320 PKKPSPQPSSPRQVKRAV-----VVSPKEENKAAEPPPPKIPKIE--TTHPPLPPAHPPP 372
Query: 577 --LPP-----GAPPPPPP-----------PPPGSAGMMYAPPPPP--PPPMDPSNFVTMM 616
PP G PP P PPP ++ PPP P PPP PS+++T M
Sbjct: 373 DRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGM 432
Query: 617 ----------------------GMGVAGMPPFGMPPA---------PPPPPP 637
G +PP PPA PP PPP
Sbjct: 433 STTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPP 484
Score = 65.5 bits (158), Expect = 1e-10
Identities = 58/193 (30%), Positives = 76/193 (39%), Gaps = 50/193 (25%)
Query: 461 YRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPS-GPLPPWQQQQ--QQPPPPPPPSSSM 517
++L Q + P P + + P S +P P P P QQQQ QQP P P SS
Sbjct: 271 HQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSS- 329
Query: 518 ASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPL 577
P Q + P ++ +AA P P+++ PPL
Sbjct: 330 ------PRQVKRAVV--------VSPKEENKAAEPPPPKIPKIETT----------HPPL 365
Query: 578 PPGAPPPPPPPPPGSAGMMYAPPPPP-----------PPPMDPSNFVTMMGMGVAGMPPF 626
PP A PPP PP +A + A PP P PPP P+ V PP
Sbjct: 366 PP-AHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAP--------VHQPPP- 415
Query: 627 GMPPAPPPPPPQN 639
+P PPPPPP +
Sbjct: 416 -LPHRPPPPPPSS 427
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 103 bits (258), Expect = 4e-22
Identities = 97/366 (26%), Positives = 125/366 (34%), Gaps = 60/366 (16%)
Query: 322 EAPVPASVGSTSGPATTPLASAPR----PAAPANNPPPPSLMSTTQSRPPWMNS------ 371
+ P S+ S++ P ++P S P P APA+ P P RPP +
Sbjct: 226 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAH-PSQPKPKGLQALRPPQVTPPRKDAA 284
Query: 372 ---GPSESRPYHGMHGGGPGGPGGGP--HSFPHP-------------LPSLTGGHGGHPM 413
GP S P P P P + P P P+L H P
Sbjct: 285 PALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 344
Query: 414 QH-NPNGPPPPWMQPPP----PPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKG 468
+P PPP Q PP PP+ P PP PP+ +P +H +
Sbjct: 345 PPLSPLATPPP--QAPPALALPPLQAPPSPPAS---PPLSPLATPSPQAPNALAVHLLQA 399
Query: 469 MMPPPP----MGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLP 524
PPP PP PP PPS P Q PP PP S M+ S P
Sbjct: 400 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP 459
Query: 525 WQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGN-PTMVPLPPGVQPPLPPGAPP 583
Q PP A P + P P P P+ P A P
Sbjct: 460 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 519
Query: 584 PPPPPPPGSAGMMYAPPPPP----------PPPMDPSNFVTMMGMGVAGMPPFGMPPAPP 633
PP PP +A ++ PP PP PP P V+ + +A + P PP
Sbjct: 520 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA------LAPGPP 573
Query: 634 PPPPQN 639
PPP ++
Sbjct: 574 PPPSRS 579
Score = 73.9 bits (180), Expect = 4e-13
Identities = 89/314 (28%), Positives = 110/314 (35%), Gaps = 60/314 (19%)
Query: 325 VPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHG 384
+P S PA+ PL+ P+ A N L+ S PP P P+
Sbjct: 363 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP----SPPVQAPF----- 413
Query: 385 GGPGGPGGGPHSFP--HPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHP---- 438
P P P + P PSL P+Q P+ P P M P P Q P P
Sbjct: 414 SPPASPPVSPSATPPSQAPPSLAAP----PLQVPPSPPASPPMSPSATPPPQAPPPLAAP 469
Query: 439 ------PGHHGPP----PMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQ 488
P PP P Q L S P +P P+ PP PP
Sbjct: 470 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 529
Query: 489 P--PPPPSGPLPPWQQQQQQPP--------------------PPPPPSSSMAS--STPLP 524
P PPS P P Q ++PP PPPPPS S +S S P
Sbjct: 530 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL 589
Query: 525 WQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPL----PPG 580
+++ T+T + AAA+ P A +P P PPL PG
Sbjct: 590 AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA--PPLAFRGAPG 647
Query: 581 APPP-PPPPPPGSA 593
AP P PP PGSA
Sbjct: 648 APLPWPPATGPGSA 661
Score = 63.9 bits (154), Expect = 4e-10
Identities = 88/377 (23%), Positives = 117/377 (31%), Gaps = 88/377 (23%)
Query: 336 ATTPLASAP---RPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGG 392
A TP A AP P P + PPP + T + + + + R GG GG
Sbjct: 14 ARTPAARAPGLLTPRPPGSPRPPPPV---TPAALRVLGAAGAVGRKPLAERAGGIGG-AT 69
Query: 393 GPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLG 452
P S P P+ T P PP P P++ G P P+ Q
Sbjct: 70 IPESAPRAGPTRTS----RPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 125
Query: 453 STPVGSGVYRLHQGKGMMPP---------------PPMGMMPP---------------PP 482
V R GK P P G P P
Sbjct: 126 RISAEETVAR---GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 182
Query: 483 PPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIP 542
P PS +P PP GP + P P++ S Q+ + + +S+ T
Sbjct: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 242
Query: 543 PWQQQQAA-----AAASPGAPQMQGNPTMVPLPPGVQPPLPPGAP--------------- 582
P + +A A A P P+ +G + PP V PP AP
Sbjct: 243 PARSGPSARGTPRAPAHPSQPKPKGLQAL--RPPQVTPPRKDAAPALGPLSSSPLATPSP 300
Query: 583 -PPPPPPPPGSAGMMYAPPPPPP---------------------PPMDPSNFVTMMGMGV 620
PP P P S + +PP PP PP+ P
Sbjct: 301 SAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA 360
Query: 621 AGMPPFGMPPAPPPPPP 637
+PP PP+PP PP
Sbjct: 361 LALPPLQAPPSPPASPP 377
Score = 59.7 bits (143), Expect = 8e-09
Identities = 78/316 (24%), Positives = 100/316 (31%), Gaps = 98/316 (31%)
Query: 320 LGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPY 379
L P+ + P +P A+ P A P PP L PP + + P ++ P
Sbjct: 435 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP- 493
Query: 380 HGMHGGGPGGPGGGPHSFPHPLP-SLTGGHGGHPMQHNPNGPPP----PWMQ-PPPPPMN 433
P SFP P S + P+ P PP P +Q PP PP +
Sbjct: 494 ------------SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 541
Query: 434 ---QGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPP 490
Q P P GP T V P + + P PPPPPS P
Sbjct: 542 PTLQAPRRPPTPGP--------DTSVSG------------PRLTLALAPGPPPPPSRSPS 581
Query: 491 PPPSGPLPPWQQQQQQPPP----------------PPPPSSSMASSTPLPWQQNTTTTTT 534
SGP P PPP + +A+ P W +
Sbjct: 582 STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR------- 634
Query: 535 SAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPL------------PPGAP 582
G PP A +PGAP +P PP P P A
Sbjct: 635 ----GPAPP-----LAFRGAPGAP--------LPWPPATGPGSADGLCTIYETEGPESAT 677
Query: 583 PPP----PPPPPGSAG 594
P P P P PG++G
Sbjct: 678 PAPGALDPGPSPGTSG 693
>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
sapiens]
Length = 247
Score = 103 bits (256), Expect = 6e-22
Identities = 75/213 (35%), Positives = 85/213 (39%), Gaps = 34/213 (15%)
Query: 410 GHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHG----PPPMDQYLGSTPVGSGVYR--- 462
G P P G P PPPP QGP P G + PPP + G P G +
Sbjct: 34 GKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPP 93
Query: 463 LHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPP------PPSSS 516
H GK PPP G PPP G+P PP P Q +PPPPP PP
Sbjct: 94 PHPGKPERPPPQGGNQSQGTPPPPGKPERPP----PQGGNQSHRPPPPPGKPERPPPQGG 149
Query: 517 MASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASP-----GAPQMQGNPTMVPLPP 571
S P P PP + ++ +A SP G PQ +GN P PP
Sbjct: 150 NQSQGPPPHPGKPEGP---------PPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPP 200
Query: 572 GV-QPPLPPGAPPPPPPPPPGSAGMMYAPPPPP 603
G Q P P G P P PP AG PPPPP
Sbjct: 201 GKPQGPPPAGGNPQQPQAPP--AGKPQGPPPPP 231
Score = 78.2 bits (191), Expect = 2e-14
Identities = 64/196 (32%), Positives = 65/196 (33%), Gaps = 42/196 (21%)
Query: 463 LHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPP------PPSSS 516
L GK P G P PPPP G+P PP P Q Q PPPPP PP
Sbjct: 31 LISGKPEGRRPQGGNQPQRPPPPPGKPQGPP----PQGGNQSQGPPPPPGKPEGRPPQGG 86
Query: 517 MASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPP 576
S P P G PP Q S G P G P P G Q
Sbjct: 87 NQSQGPPP----------HPGKPERPPPQ----GGNQSQGTPPPPGKPERPPPQGGNQSH 132
Query: 577 LPPGAPPPPPPPPPGSAGMMYAPPP-------PPP-----------PPMDPSNFVTMMGM 618
PP P P PPP PPP PPP PP P G
Sbjct: 133 RPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGN 192
Query: 619 GVAGMPPFGMPPAPPP 634
G PP G P PPP
Sbjct: 193 KPQGPPPPGKPQGPPP 208
Score = 77.8 bits (190), Expect = 3e-14
Identities = 67/202 (33%), Positives = 76/202 (37%), Gaps = 42/202 (20%)
Query: 345 RPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSL 404
RP P P P QS+ P G E RP G G G PH P
Sbjct: 49 RPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQG----GNQSQGPPPHPGKPERPPP 104
Query: 405 TGGH---GGHPMQHNPNGPPPPW----MQPPPPP------------MNQGP--HPPGHHG 443
GG+ G P P PPP +PPPPP +QGP HP G
Sbjct: 105 QGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEG 164
Query: 444 PPPMD---QYLGSTPVGS--GVYRLHQGKGMMPPPPMGMMPPPPP---------PPSGQP 489
PPP + +P G G + K PPPP PPP PP+G+P
Sbjct: 165 PPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAGKP 224
Query: 490 ---PPPPSGPLPPWQQQQQQPP 508
PPPP G PP Q QQPP
Sbjct: 225 QGPPPPPQGGRPPRPAQGQQPP 246
Score = 69.7 bits (169), Expect = 8e-12
Identities = 59/203 (29%), Positives = 70/203 (34%), Gaps = 39/203 (19%)
Query: 322 EAPVPASVGSTSGPATTPLASAPRPAAPANNP------------PPPSLMSTTQSRPPWM 369
+ P P + GP P RP N PPP + +Q PP
Sbjct: 58 QGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPP 117
Query: 370 NSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPP------- 422
P P G P P G P P + + G HP + P GPPP
Sbjct: 118 GK-PERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGK--PEGPPPQEGNKSR 174
Query: 423 ----PWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMM 478
P +P PP +G P GPPP + G P G G P P
Sbjct: 175 SARSPPGKPQGPPQQEGNKP---QGPPPPGKPQGPPPAG--------GNPQQPQAPPAGK 223
Query: 479 P--PPPPPPSGQPPPPPSGPLPP 499
P PPPPP G+PP P G PP
Sbjct: 224 PQGPPPPPQGGRPPRPAQGQQPP 246
Score = 43.5 bits (101), Expect = 6e-04
Identities = 26/67 (38%), Positives = 26/67 (38%), Gaps = 5/67 (7%)
Query: 572 GVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPA 631
G QP PP P P PPP PPPPP P G G PP P
Sbjct: 44 GNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPG---KPEGRPPQGGNQSQGPPPH--PGK 98
Query: 632 PPPPPPQ 638
P PPPQ
Sbjct: 99 PERPPPQ 105
Score = 43.1 bits (100), Expect = 8e-04
Identities = 32/83 (38%), Positives = 33/83 (39%), Gaps = 23/83 (27%)
Query: 574 QPPLPPGAP--PPP--------PPPPPGSAGMMYAPPP--------PPPPPMDPSNFVTM 615
+PP PPG P PPP PPPPPG PP PPP P P
Sbjct: 49 RPPPPPGKPQGPPPQGGNQSQGPPPPPGKPE---GRPPQGGNQSQGPPPHPGKPERPPPQ 105
Query: 616 MGMGVAGMPPFGMPPAPPPPPPQ 638
G G PP P P PPPQ
Sbjct: 106 GGNQSQGTPP--PPGKPERPPPQ 126
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 102 bits (254), Expect = 1e-21
Identities = 91/271 (33%), Positives = 98/271 (36%), Gaps = 60/271 (22%)
Query: 382 MHGGGPGGPGGGPHSFPHP--------LPSLTGGHGGHPMQHNPNGPPPPW---MQPPPP 430
M G G GP GG P P G P P GPPPP+ PP P
Sbjct: 180 MSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRP 239
Query: 431 PMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQP- 489
P+ P PPG GPPP Q L G PP G PPPP GQP
Sbjct: 240 PLGP-PGPPGPPGPPPPGQVLPPPLAG--------------PPNRGDRPPPPVLFPGQPF 284
Query: 490 PPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQA 549
PP GPLPP PPPP P P P Q G PP
Sbjct: 285 GQPPLGPLPPG-------PPPPVPGYGPPPGPPPPQQ------------GPPPP------ 319
Query: 550 AAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPP------PPPGSAGMMYAPPPPP 603
P P G P + PP + P PPGAPPP P PPP ++GM + P
Sbjct: 320 PGPFPPRPPGPLGPPLTLAPPPHLPGP-PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGP 378
Query: 604 PPPMDPSNFVTMMGMGVAGMPPFGMPPAPPP 634
PP DP G G P M A P
Sbjct: 379 -PPTDPYGRPPPYDRGDYGPPGREMDTARTP 408
Score = 92.4 bits (228), Expect = 1e-18
Identities = 72/213 (33%), Positives = 81/213 (38%), Gaps = 48/213 (22%)
Query: 428 PPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSG 487
PP ++ P G G ++ G+ P G P P G PPPP P+G
Sbjct: 188 PPGGSSRAAFPQGGRG---RGRFPGAVPGGDRF-----------PGPAGPGGPPPPFPAG 233
Query: 488 QPPP-PPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQ 546
Q PP PP GP P P PP PP PL N G PP
Sbjct: 234 QTPPRPPLGPPGP-------PGPPGPPPPGQVLPPPLAGPPNR---------GDRPP--- 274
Query: 547 QQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPP 606
PG P G P + PLPPG PP+P PPP PPPP PPPPP P
Sbjct: 275 ---PPVLFPGQPF--GQPPLGPLPPGPPPPVPGYGPPPGPPPPQQG-------PPPPPGP 322
Query: 607 MDPSNFVTMMGMGVAGMPPF--GMPPAPPPPPP 637
P + PP G PP PPP P
Sbjct: 323 FPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAP 355
Score = 82.8 bits (203), Expect = 9e-16
Identities = 64/188 (34%), Positives = 73/188 (38%), Gaps = 23/188 (12%)
Query: 321 GEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH 380
G P P G T P PL P P P PPP ++ + PP P +
Sbjct: 224 GGPPPPFPAGQT--PPRPPLGP-PGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFP 280
Query: 381 GMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPG 440
G G P G P P P+P G+G P GPPPP PPPPP P PPG
Sbjct: 281 GQPFGQPP-LGPLPPGPPPPVP----GYGPPP------GPPPPQQGPPPPPGPFPPRPPG 329
Query: 441 HHGPP---PMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMP------PPPPPPSGQPPP 491
GPP +L P G+ H PPP MP PPP P G+PPP
Sbjct: 330 PLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389
Query: 492 PPSGPLPP 499
G P
Sbjct: 390 YDRGDYGP 397
Score = 82.0 bits (201), Expect = 2e-15
Identities = 74/226 (32%), Positives = 88/226 (38%), Gaps = 29/226 (12%)
Query: 364 SRPPWMNSGPSESRPYHGMHGG----GPGGPGGGPHSFPH----PLPSLTGGHGGHPMQH 415
SR + G R + GG GP GPGG P FP P P L G P
Sbjct: 193 SRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPL-----GPPGPP 247
Query: 416 NPNGPPPPWMQPPPP---PMNQGPHPPGHHGPPPM--DQYLGSTPVGS---GVYRLHQGK 467
P GPPPP PPP P N+G PP PP + Q G P+G G G
Sbjct: 248 GPPGPPPPGQVLPPPLAGPPNRGDRPP----PPVLFPGQPFGQPPLGPLPPGPPPPVPGY 303
Query: 468 GMMP-PPPMGMMPPPPPPPSGQPPPPPSGP---LPPWQQQQQQPPPPPPPSSSMASSTPL 523
G P PPP PPPPP P PP P GP L P PP PPP+ + +
Sbjct: 304 GPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFP 363
Query: 524 PWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPL 569
P + T+ S G P+ + G P + + PL
Sbjct: 364 PPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPL 409
Score = 50.1 bits (118), Expect = 6e-06
Identities = 45/155 (29%), Positives = 57/155 (36%), Gaps = 24/155 (15%)
Query: 321 GEAPVPASV--GSTSG-PATTPLASAPRPAAPANNPPP---------PSLMSTTQSRPPW 368
G+ P P + G G P PL P P P PPP P RPP
Sbjct: 270 GDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPG 329
Query: 369 MNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPP--PWMQ 426
P P + G PG P PH P P T + G P + GPPP P+ +
Sbjct: 330 PLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPT--NSGMPTSDS-RGPPPTDPYGR 386
Query: 427 PPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVY 461
PPP + G +GPP + TP+ +
Sbjct: 387 PPP-------YDRGDYGPPGREMDTARTPLSEAEF 414
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 101 bits (252), Expect = 2e-21
Identities = 98/343 (28%), Positives = 123/343 (35%), Gaps = 54/343 (15%)
Query: 323 APVPASV------GSTSGPATTPLASAPRPAAPANNPPPPS-----LMSTTQSRPPWMNS 371
AP P++V G T P TP S P P P+ +S T S P +
Sbjct: 864 APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARA 923
Query: 372 GPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPP 431
P+ G P P P P P + G P +P P P PP P
Sbjct: 924 TPAPK--------GIPASPS--PKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSP 973
Query: 432 MNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPP 491
GP P G P +P G G P P G P PP+ PP
Sbjct: 974 KG-GPATPSPKGAPTPPAATPPSPKG----------GPATPSPKG----APTPPAVTPPS 1018
Query: 492 PPSGP-LPPWQQQQQQPPPPPPPS-SSMASSTPLPWQQNTT---TTTTSAGTGSIPPWQQ 546
P P P+ + PP PPS ++TPLP TT T + G + P +
Sbjct: 1019 PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG 1078
Query: 547 QQAAAAASPGAPQ---MQGNPTMVPLPPGVQPPLP---------PGAPPPPPPPPPGSAG 594
AA+P +P+ +P P+PP PP P GAP P PP G
Sbjct: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138
Query: 595 MMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPPP 637
+ A PPP P P+ G+A PP G P P PP
Sbjct: 1139 GL-ATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1180
Score = 95.1 bits (235), Expect = 2e-19
Identities = 108/386 (27%), Positives = 131/386 (33%), Gaps = 66/386 (17%)
Query: 298 GDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATT-------PLASAPR--PAA 348
G P S K + + G P+ + + PA T P +P+ P
Sbjct: 929 GIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP 988
Query: 349 PANNPPPPSLMSTTQS----------RPPWMNSGPSESRPYHGMH---GGGPGGPGGGPH 395
PA PP P T S PP P+ + G P P G P
Sbjct: 989 PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA 1048
Query: 396 SFPHP----------LPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPP 445
+ P P LPS GG P + G P P PP P GP P G P
Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGG----PATPSLKGAPTPPAATPPSPKG-GPATPSPKGAP 1103
Query: 446 PMDQYLGSTPVGSGVYRLHQG----KGMMPPPPMGMMPPPPP-----PPSGQPPPPPSGP 496
+P G H+G PP P G + PPP P+ PP P G
Sbjct: 1104 MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1163
Query: 497 LPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPG 556
P + P PPS +TP P TT T PP + A + G
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT-------PPSPKGGLATPSPKG 1216
Query: 557 APQMQGNPTMVPLPP--GVQPPLPPGAPPPPPPPPPGSAGMMYAPPP---PPPPPMDPSN 611
AP P P P G+ P P GAP P PP G PPP P PP P +
Sbjct: 1217 APT---TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPS 1273
Query: 612 FVTMMGMGVAGMPPFGMP-PAPPPPP 636
+ G+A P G P PA PP
Sbjct: 1274 ----LKGGLATPPHKGAPNPAVVTPP 1295
Score = 93.6 bits (231), Expect = 5e-19
Identities = 106/396 (26%), Positives = 127/396 (32%), Gaps = 83/396 (20%)
Query: 317 MAELGEAP-VPASVGSTS-GPATTP------------LASAPRPAAPANNPPPPSLMSTT 362
+A L AP +P SV S S PA TP A AP ++P P S S T
Sbjct: 721 LATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASAT 780
Query: 363 QSR------------PPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLP-------- 402
S P ++ P RP GP P G S P+
Sbjct: 781 ASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS 840
Query: 403 -SLTGGHGGHPMQHNPNGPPP--------------------PWMQPPPPPMN-----QGP 436
S G H+P P P P P P +N +GP
Sbjct: 841 LSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP 900
Query: 437 HPPGHHGPPPMDQYLGS------TPVGSGVYRLHQGKGMMPPPPMGMMPPP--------- 481
P P + S TP G+ KG P PP P P
Sbjct: 901 ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGA-PTPPAATPPSPKGGPATPSP 959
Query: 482 ---PPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGT 538
P PP+ PP P GP P + PP PPS +TP P T T
Sbjct: 960 KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSP 1019
Query: 539 GSIPPWQQQQAAAAASPGA--PQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMM 596
P A+ P A P +G+P PLP G P P A P P P + +
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGA--PTTPAATLPSPKGGPATPSLK 1077
Query: 597 YAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAP 632
AP PP P P A MPP PP+P
Sbjct: 1078 GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSP 1113
Score = 93.2 bits (230), Expect = 7e-19
Identities = 97/348 (27%), Positives = 117/348 (33%), Gaps = 50/348 (14%)
Query: 326 PASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGG 385
PA+ G TTP A+ P P P + + PP GP+ P G
Sbjct: 1047 PAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK-----G 1101
Query: 386 GPGGPGGGPHSFPHPLPSL-TGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGP 444
P P P P P L T H G P P P PPP P P P
Sbjct: 1102 APMPPAATP---PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKG-APTTPAATPP 1157
Query: 445 PPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPP-----PSGQPPPPPSGPLPP 499
P P G+ PP P G + P P P+ PP P G P
Sbjct: 1158 SPKGGLATPPPKGAPTT-----PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212
Query: 500 WQQQQQQPPPPPPPSSSMASSTPLPWQQNTT---TTTTSAGTGSIPPWQQQQAAAAASPG 556
+ P PPS +TP P TT T + G + PP + AA+P
Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP- 1271
Query: 557 APQMQG-----------NPTMV--PLPPGVQPPLPP-GAPPPPPPPPPGSAGMMYAPPP- 601
P ++G NP +V P P G PP GAP PP PP G PPP
Sbjct: 1272 -PSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330
Query: 602 --PPPPPMDPSN--------FVTMMGMGVAGMPPFGMPPAPPPPPPQN 639
P PP + P + T G P P PP P +
Sbjct: 1331 GAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378
Score = 88.6 bits (218), Expect = 2e-17
Identities = 90/331 (27%), Positives = 104/331 (31%), Gaps = 67/331 (20%)
Query: 334 GPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGG 393
G TTP A+ P P PPP +T + PP G + P G P P
Sbjct: 1124 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPK-----GAPTTPAAT 1178
Query: 394 PHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGS 453
P PS GG +P G P PP P G P G P
Sbjct: 1179 P-------PSPKGGLA----TPSPKGAPTTPAATPPSPKG-GLATPSPKGAPTTPAATPP 1226
Query: 454 TPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPP 513
+P G G+ P P G P P+ PP P GP P + PP PP
Sbjct: 1227 SPKG----------GLATPSPKGA----PTTPAATPPSPKGGPATPPPKGAPTPPAATPP 1272
Query: 514 SSSMASSTP----LPWQQNTTTTTTSAGTGSIPPWQQQQAAAAA------SPGAPQMQGN 563
S +TP P T + G + PP AA SPG P +G
Sbjct: 1273 SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA 1332
Query: 564 PTMVPLPPGVQPPLPPGAPP----------------------PPPPPPPGSAGMMYAPPP 601
PT PP V PP P G P PP P G PP
Sbjct: 1333 PT----PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPS 1388
Query: 602 PPPPPMDPSNFVTMMGMGVAGMPPFGMPPAP 632
P P PS V + P P P
Sbjct: 1389 PKRGPAIPSPKGDPTSPAVIPLSPKKAPATP 1419
Score = 69.3 bits (168), Expect = 1e-11
Identities = 91/364 (25%), Positives = 118/364 (32%), Gaps = 78/364 (21%)
Query: 323 APVPASVGSTS---GPATTPLASAPRPAA-----PANNP--PPPSLMSTTQSRPPWMNSG 372
AP PA V S GPAT+P AP P A P +P PPP T + P G
Sbjct: 1286 APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345
Query: 373 PSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQH-----------NPNGPP 421
GGP P P P+ T H G P +P G P
Sbjct: 1346 TPTLPATTPSSKGGPTTPSSKEGPTP---PAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402
Query: 422 P--------PWMQPPPPPMNQGPHPP--GHHGPPPMDQY------LGSTPVGSGVYRLHQ 465
P P P +G P G PP + S P G +
Sbjct: 1403 TSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSK 1462
Query: 466 GKGMMPP--PPMGMMPPPP---------------PPPSGQPPPP---PSGPLPPWQQQQQ 505
G +P PP PP P P P G P P PS P
Sbjct: 1463 GDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSS 1522
Query: 506 QPPPPPPPSSSMASSTP---------------LPWQQNTTTTTTSAGTGSIPPWQQQQAA 550
+ P P ++ ++ TP +P + T T + P ++ +
Sbjct: 1523 RRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSP 1582
Query: 551 AAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPP---PPPPPM 607
A +P + +P + +PP V P P AP PP PP P P P PP+
Sbjct: 1583 PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPV 1642
Query: 608 DPSN 611
PS+
Sbjct: 1643 TPSS 1646
Score = 65.9 bits (159), Expect = 1e-10
Identities = 87/339 (25%), Positives = 111/339 (32%), Gaps = 50/339 (14%)
Query: 324 PVPASVGSTSGP-ATTPLA-----SAPRPAAPANNPPPPSL----MSTTQSRPPWMNSGP 373
PV S +T P AT LA S P P+ P PP + +S T + P + S P
Sbjct: 709 PVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAP-VASSP 767
Query: 374 SESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMN 433
E G G ++ PS G P +PP +
Sbjct: 768 KECPTEDS--GASATASSKGTLTYLADSPSPLGV-----------SVSPQTKRPPTKKGS 814
Query: 434 QGPHPP-GHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPP 492
GP P G+ P P S + QG P P PP P G P P
Sbjct: 815 AGPDTPIGNLSSPVSPVEASFLPENSLSF---QGS---KDSPATTHSPTPPSPKGAPTPS 868
Query: 493 PSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAA 552
PL P + PP P+ S+ + P P + T A S+ ++A A
Sbjct: 869 AVTPLSP---KGVTLPPKETPTPSVVN-LPFPKEGPATPAPKQAPALSMTSSSPKKARAT 924
Query: 553 ASPGAPQMQGNPTMVPLPPGVQPP---------------LPPGAPPPPPPPPPGSAGMMY 597
+P +P P PP PP PP A PP P P +
Sbjct: 925 PAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKG 984
Query: 598 APPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPP 636
AP PP P P A PP PP+P P
Sbjct: 985 APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023
Score = 58.9 bits (141), Expect = 1e-08
Identities = 78/323 (24%), Positives = 105/323 (32%), Gaps = 19/323 (5%)
Query: 326 PASVGSTSGPATT-----PLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH 380
PA+ GPAT P A P +P P P + +++ + P +
Sbjct: 1447 PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP 1506
Query: 381 GMHGGGPGGPGGGPHSFPHPL-PSLTGGHGGHPMQHNPNGPP-PPWMQPPPPPMNQGPHP 438
+ P P S P+ P+ T P P PP M P P
Sbjct: 1507 AVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPT 1566
Query: 439 PGHHGPPPMDQYLGSTP-VGSGVYRLHQGKGMMPPPPMGMMPPP---PPPPSGQPPPPPS 494
P P + S P V Y+ + PP P P P PP+ PP P
Sbjct: 1567 PKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEK 1626
Query: 495 GPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAAS 554
GP P + PP P S + ++P T A G P ++ A
Sbjct: 1627 GPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL--PAKKGPTALKEV 1684
Query: 555 PGAPQMQGNPTM-VPLPPGVQPPLPPGAPPPPPPPPP---GSAGMMYAPPPPPPPPMDPS 610
AP + P + P G Q PP P P GS G + P P P+
Sbjct: 1685 LVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKD 1744
Query: 611 NFVTMMGMGVAGMPPFGMPPAPP 633
+ T G + P P APP
Sbjct: 1745 SSKTAKGKDASHSPK--GPLAPP 1765
Score = 50.8 bits (120), Expect = 4e-06
Identities = 76/324 (23%), Positives = 106/324 (32%), Gaps = 36/324 (11%)
Query: 322 EAPV-PASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH 380
EAP P+S ++S PA TP P+ P PP++ S + P P P
Sbjct: 1569 EAPATPSSKEASSPPAVTPSTYKGAPS-PKELLIPPAVTSPSPKEAPT----PPAVTPPS 1623
Query: 381 GMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPG 440
G P G P S P SL + +P P + P
Sbjct: 1624 PEKGPATPAPKGTPTSPPVTPSSL---------KDSPTSPASVTCKMGATVPQASKGLPA 1674
Query: 441 HHGPPPMDQYL-GSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPS------GQPPPPP 493
GP + + L P + + KG PP P PS G
Sbjct: 1675 KKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVA 1734
Query: 494 SGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAA 553
PL P Q+ + S S P + +T T +A +P + +AA
Sbjct: 1735 PAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAP 1794
Query: 554 SPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFV 613
SP P +PL P P LPP P P G++ P P P D +
Sbjct: 1795 SP--------PVSLPLAPSPVPTLPPKQQFLPSSP-----GLVLESPSKPLAPADEDELL 1841
Query: 614 TMM-GMGVAGMPPFGMPPAPPPPP 636
++ ++G PF P P
Sbjct: 1842 PLIPPEPISGGVPFQSVLVNMPTP 1865
Score = 47.8 bits (112), Expect = 3e-05
Identities = 75/329 (22%), Positives = 106/329 (32%), Gaps = 54/329 (16%)
Query: 326 PASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSR-------------PPWMNSG 372
PA +G+ + PA P + PA P++ P + +T S+ PP M
Sbjct: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVP 1556
Query: 373 PSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQ----------HNPNGPPP 422
+ P P P S P + T P + P P
Sbjct: 1557 SPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP 1616
Query: 423 PWMQPPPPPMNQGPHPPGHHG----PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMM 478
P + PP P +GP P G PP L +P G +P G+
Sbjct: 1617 PAVTPPSP--EKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMG-ATVPQASKGLP 1673
Query: 479 PPPPPPPSGQ---PPPPPSGPL--PPWQQQQQ-------QPPPPPPPSSSMASSTPLPWQ 526
P + P P S P+ P ++ Q PP P PS+ S PL
Sbjct: 1674 AKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPL--- 1730
Query: 527 QNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPP 586
++ + P Q+ + A A P + P PL A
Sbjct: 1731 -------STVAPAPLLPVQKDSSKTAKGKDASHSPKGP-LAPPESKASTPLTAAAFEKVL 1782
Query: 587 PPPPGSAGMMYAPPPPPPPPMDPSNFVTM 615
P P SA + AP PP P+ PS T+
Sbjct: 1783 PKPE-SASVSAAPSPPVSLPLAPSPVPTL 1810
Score = 38.5 bits (88), Expect = 0.019
Identities = 44/146 (30%), Positives = 57/146 (39%), Gaps = 27/146 (18%)
Query: 487 GQPPPPPSGPLPPWQQQ-----QQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS- 540
GQP P P P QQ Q P P PS+ ++ +P+ Q+++ T GT
Sbjct: 39 GQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPE 98
Query: 541 --------IPPWQQQQAAAAASPG-APQMQGNP-TMVPL------PPGVQ-----PPLPP 579
I P A A ASP AP ++G P + PL P VQ PP
Sbjct: 99 APTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLL 158
Query: 580 GAPPPPPPPPPGSAGMMYAPPPPPPP 605
+PP GS + AP P P
Sbjct: 159 TSPPSVAVAESGSVITLSAPIAPSEP 184
Score = 33.5 bits (75), Expect = 0.62
Identities = 55/238 (23%), Positives = 81/238 (34%), Gaps = 45/238 (18%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMH 383
P P++ + GP +T AP P P + S P P ES+ +
Sbjct: 1718 PDPSAKNGSKGPLSTV---APAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLT 1774
Query: 384 GGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHG 443
+F LP P + + P P P P+ P P
Sbjct: 1775 AA----------AFEKVLPK--------PESASVSAAPSP---PVSLPLAPSPVPT---- 1809
Query: 444 PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQ 503
PP Q+L S+P G+ K + P ++P PP P SG +P Q
Sbjct: 1810 LPPKQQFLPSSP---GLVLESPSKPLAPADEDELLPLIPPEPI-------SGGVP---FQ 1856
Query: 504 QQQPPPPPPPSSSMASSTPLPWQ----QNTTTTTTSAGTGSIPPWQQQQAAAAASPGA 557
P P S+ + TP Q N + T S S+P ++Q + A + A
Sbjct: 1857 SVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQA 1914
Score = 32.7 bits (73), Expect = 1.1
Identities = 27/109 (24%), Positives = 38/109 (34%), Gaps = 16/109 (14%)
Query: 543 PWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPP--------PGSAG 594
P + + A PQ Q ++P+ + G P P PPP P SA
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
Query: 595 MMYAPPPPPPP--------PMDPSNFVTMMGMGVAGMPPFGMPPAPPPP 635
+P P P P S+ T + +G A P +P PP
Sbjct: 62 NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPP 110
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 100 bits (250), Expect = 3e-21
Identities = 103/318 (32%), Positives = 117/318 (36%), Gaps = 98/318 (30%)
Query: 346 PAAPANNP----PPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPL 401
P+ PA P PPP LM+ RPP S P P PGG P P+
Sbjct: 221 PSLPAGPPGVKRPPPPLMNGLPPRPPLPESLP-------------PPPPGGLPLP---PM 264
Query: 402 PSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVY 461
P P P+GPP P PPP P G HPP PP G P GV+
Sbjct: 265 P---------PTGPAPSGPPGPPQLPPPAP---GVHPPAPVVHPPAS---GVHPPAPGVH 309
Query: 462 RLHQGKGMMPPPPMGMMPPPP---PPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMA 518
PP G+ PP P PP SG PP P G PP P PP+ +
Sbjct: 310 ----------PPAPGVHPPAPGVHPPTSGVHPPAP-GVHPPAPGVHPPAPGVHPPAPGVH 358
Query: 519 SSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQ-GNPTMVPLPPGVQPPL 577
P G PP +A P AP + P + P PGV PP
Sbjct: 359 PPAP----------------GVHPP-----PSAGVHPQAPGVHPAAPAVHPQAPGVHPPA 397
Query: 578 P------PGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGV---AGMPPFGM 628
P PG P PP P + G+ P PP + PSN GV MPP
Sbjct: 398 PGMHPQAPGVHPQPPGVHPSAPGV-----HPQPPGVHPSN------PGVHPPTPMPPMLR 446
Query: 629 PPAP-------PPPPPQN 639
PP P PPPPP N
Sbjct: 447 PPLPSEGPGNIPPPPPTN 464
Score = 80.1 bits (196), Expect = 6e-15
Identities = 71/217 (32%), Positives = 84/217 (38%), Gaps = 38/217 (17%)
Query: 425 MQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMG-MMPPPPP 483
M+ PP P + PPG PPP P+ +G + P PP+ +PPPPP
Sbjct: 214 MEKPPAPPSLPAGPPGVKRPPP--------PLMNG---------LPPRPPLPESLPPPPP 256
Query: 484 PPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPP 543
PP PP+GP P Q PPP P P P + G PP
Sbjct: 257 GGLPLPPMPPTGPAPSGPPGPPQLPPPAP-----GVHPPAPVVHPPASGVHPPAPGVHPP 311
Query: 544 WQQQQAAAAASPGAPQMQGNPTMV-PLPPGVQPPLPPGAPPPP--PPPPPGSAGMMYAPP 600
A P AP + + V P PGV PP P PP P PP PG ++ P
Sbjct: 312 ------APGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPG----VHPPA 361
Query: 601 PPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPPP 637
P PP PS V GV P P AP PP
Sbjct: 362 PGVHPP--PSAGVHPQAPGVHPAAPAVHPQAPGVHPP 396
Score = 75.1 bits (183), Expect = 2e-13
Identities = 66/205 (32%), Positives = 77/205 (37%), Gaps = 36/205 (17%)
Query: 322 EAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSL--------MSTTQSRPPWMN--- 370
+ P PA P P AS P AP +PP P + T+ PP
Sbjct: 279 QLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHP 338
Query: 371 SGPSESRPYHGMHGGGPGGPGGGPHSFPHPL----PSLTGGHGGHPMQHNPNGPPPPWMQ 426
P P G+H PG P P P P G H P H P P +
Sbjct: 339 PAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVH----PQAPGVH 394
Query: 427 PPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPS 486
PP P M+ P PG H PP G P GV+ Q G+ P P G+ PP P PP
Sbjct: 395 PPAPGMH--PQAPGVHPQPP-----GVHPSAPGVH--PQPPGVHPSNP-GVHPPTPMPPM 444
Query: 487 GQPPPPPSGPLPPWQQQQQQPPPPP 511
+PP P GP PPPPP
Sbjct: 445 LRPPLPSEGP-------GNIPPPPP 462
Score = 50.4 bits (119), Expect = 5e-06
Identities = 29/73 (39%), Positives = 33/73 (45%), Gaps = 15/73 (20%)
Query: 571 PGVQPPLPPGAPPPPPPPPPGSAGMMYAPP-----PPPPPPMDPSNFVTMMGMGVAGMPP 625
P P LP G P PPPP G+ PP PPPPP G+ + MPP
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPG----------GLPLPPMPP 266
Query: 626 FGMPPAPPPPPPQ 638
G P+ PP PPQ
Sbjct: 267 TGPAPSGPPGPPQ 279
Score = 49.7 bits (117), Expect = 8e-06
Identities = 39/126 (30%), Positives = 50/126 (39%), Gaps = 26/126 (20%)
Query: 321 GEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH 380
G P P++ P P A A P AP +PP P + + P ++ P
Sbjct: 363 GVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGM----HPQAPGVHPQPP------ 412
Query: 381 GMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPG 440
G+H PG HP P G H +P H P P PP ++PP P G PP
Sbjct: 413 GVHPSAPG---------VHPQP--PGVHPSNPGVHPPT-PMPPMLRPPLPSEGPGNIPP- 459
Query: 441 HHGPPP 446
PPP
Sbjct: 460 ---PPP 462
>gi|45827712 quaking homolog, KH domain RNA binding isoform HQK-7B
[Homo sapiens]
Length = 319
Score = 100 bits (248), Expect = 5e-21
Identities = 64/181 (35%), Positives = 100/181 (55%), Gaps = 21/181 (11%)
Query: 86 IYNSEGKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQD 145
I+N + L+ R RK + + N TE + D P ++ +K+ +P
Sbjct: 37 IFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELP-----DAVGPIVQLQEKLYVPVK 91
Query: 146 EYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKV-----GRKDGQMLPGED 200
EYP+ NFVG ++GPRG T K +E E KIM+RGKGS+++ K G+ + + L +
Sbjct: 92 EYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHL---N 148
Query: 201 EPLHALVTANTMEN-----VKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLR 255
E LH L+T +N +K+AVE+++ +L + E ++ L+KMQL ELA LNGT R
Sbjct: 149 EDLHVLITVEDAQNRAEIKLKRAVEEVKKLL---VPAAEGEDSLKKMQLMELAILNGTYR 205
Query: 256 E 256
+
Sbjct: 206 D 206
>gi|45827710 quaking homolog, KH domain RNA binding isoform HQK-7
[Homo sapiens]
Length = 325
Score = 100 bits (248), Expect = 5e-21
Identities = 64/181 (35%), Positives = 100/181 (55%), Gaps = 21/181 (11%)
Query: 86 IYNSEGKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQD 145
I+N + L+ R RK + + N TE + D P ++ +K+ +P
Sbjct: 37 IFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELP-----DAVGPIVQLQEKLYVPVK 91
Query: 146 EYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKV-----GRKDGQMLPGED 200
EYP+ NFVG ++GPRG T K +E E KIM+RGKGS+++ K G+ + + L +
Sbjct: 92 EYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHL---N 148
Query: 201 EPLHALVTANTMEN-----VKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLR 255
E LH L+T +N +K+AVE+++ +L + E ++ L+KMQL ELA LNGT R
Sbjct: 149 EDLHVLITVEDAQNRAEIKLKRAVEEVKKLL---VPAAEGEDSLKKMQLMELAILNGTYR 205
Query: 256 E 256
+
Sbjct: 206 D 206
>gi|45827708 quaking homolog, KH domain RNA binding isoform HQK-6
[Homo sapiens]
Length = 319
Score = 100 bits (248), Expect = 5e-21
Identities = 64/181 (35%), Positives = 100/181 (55%), Gaps = 21/181 (11%)
Query: 86 IYNSEGKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQD 145
I+N + L+ R RK + + N TE + D P ++ +K+ +P
Sbjct: 37 IFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELP-----DAVGPIVQLQEKLYVPVK 91
Query: 146 EYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKV-----GRKDGQMLPGED 200
EYP+ NFVG ++GPRG T K +E E KIM+RGKGS+++ K G+ + + L +
Sbjct: 92 EYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHL---N 148
Query: 201 EPLHALVTANTMEN-----VKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLR 255
E LH L+T +N +K+AVE+++ +L + E ++ L+KMQL ELA LNGT R
Sbjct: 149 EDLHVLITVEDAQNRAEIKLKRAVEEVKKLL---VPAAEGEDSLKKMQLMELAILNGTYR 205
Query: 256 E 256
+
Sbjct: 206 D 206
>gi|45827706 quaking homolog, KH domain RNA binding isoform HQK-5
[Homo sapiens]
Length = 341
Score = 100 bits (248), Expect = 5e-21
Identities = 64/181 (35%), Positives = 100/181 (55%), Gaps = 21/181 (11%)
Query: 86 IYNSEGKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQD 145
I+N + L+ R RK + + N TE + D P ++ +K+ +P
Sbjct: 37 IFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELP-----DAVGPIVQLQEKLYVPVK 91
Query: 146 EYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKV-----GRKDGQMLPGED 200
EYP+ NFVG ++GPRG T K +E E KIM+RGKGS+++ K G+ + + L +
Sbjct: 92 EYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHL---N 148
Query: 201 EPLHALVTANTMEN-----VKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLR 255
E LH L+T +N +K+AVE+++ +L + E ++ L+KMQL ELA LNGT R
Sbjct: 149 EDLHVLITVEDAQNRAEIKLKRAVEEVKKLL---VPAAEGEDSLKKMQLMELAILNGTYR 205
Query: 256 E 256
+
Sbjct: 206 D 206
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 99.8 bits (247), Expect = 7e-21
Identities = 99/312 (31%), Positives = 120/312 (38%), Gaps = 71/312 (22%)
Query: 341 ASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPH- 399
A+APRP A + P ++++ P + P RP S P
Sbjct: 120 AAAPRPPVSAASGRPQDDTDSSRASLPEL---PRMQRP-----------------SLPDL 159
Query: 400 PLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHP-PGHHGPPPMDQYLGSTPVGS 458
P+ T G M+H+ + PPPP PP N P P P H P P
Sbjct: 160 SRPNTTSSTG---MKHSSSAPPPP---PPGRRANAPPTPLPMHSSKAPAYNREKPLPPTP 213
Query: 459 GVYRLHQGKGMMPPPPMGMMPPPPPP------PSGQ---PPPPPSGPLPPWQQQQQQPPP 509
G RLH G+ P PP + PPP P PSGQ PPPPP +Q P
Sbjct: 214 G-QRLHPGREGPPAPPP--VKPPPSPVNIRTGPSGQSLAPPPPP---------YRQPPGV 261
Query: 510 PPPPSSSMASSTP-LPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMV- 567
P PSS S P LP + N+ T + P P +P+++
Sbjct: 262 PNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAP-------------PPPTSASPSLLS 308
Query: 568 --PLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPP 625
P PP PP APPPPPP G APPPPPP M S G PP
Sbjct: 309 NRPPPPARDPPSRGAAPPPPPPVIRN--GARDAPPPPPPYRMHGSE---PPSRGKPPPPP 363
Query: 626 FGMPPAPPPPPP 637
P PPPPPP
Sbjct: 364 SRTPAGPPPPPP 375
Score = 94.7 bits (234), Expect = 2e-19
Identities = 85/299 (28%), Positives = 109/299 (36%), Gaps = 60/299 (20%)
Query: 298 GDPQSAQDKARMDKEYLSLMAE--LGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPP 355
G PQ D +R L M L + P + ST ++ P P AN PP
Sbjct: 132 GRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPPGRRANAPPT 191
Query: 356 PSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQH 415
P M ++++ P + P P +H G G P P P ++ G G +
Sbjct: 192 PLPMHSSKA-PAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLA- 249
Query: 416 NPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM 475
PPPP+ QPP P GP P + P + Q S LH+ P P
Sbjct: 250 ---PPPPPYRQPPGVP--NGPSSPTNESAPELPQRHNS---------LHR---KTPGPVR 292
Query: 476 GMMPPPPPPP-----SGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTT 530
G+ PPPP S +PPPP P + PPPPPP + A P P
Sbjct: 293 GLAPPPPTSASPSLLSNRPPPPARDP----PSRGAAPPPPPPVIRNGARDAPPP------ 342
Query: 531 TTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPP 589
PP + + S G P PP P P PPPPPPPP
Sbjct: 343 -----------PPPYRMHGSEPPSRGKP-----------PP--PPSRTPAGPPPPPPPP 377
Score = 51.6 bits (122), Expect = 2e-06
Identities = 71/273 (26%), Positives = 89/273 (32%), Gaps = 75/273 (27%)
Query: 417 PNGPPPPWMQPPPPPMNQGPHPP------------------------------GHHGPPP 446
P PPPP PPPP +Q P
Sbjct: 4 PPPPPPPPGPPPPPTFHQANTEQPKLSRDEQRGRGALLQDICKGTKLKKVTNINDRSAPI 63
Query: 447 MDQYLGSTP-VGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQ 505
+++ GS+ GSG L G+ + + P S P+ +P +
Sbjct: 64 LEKPKGSSGGYGSGGAALQPKGGLFQGGVLKLRPVGAKDGSENLAGKPALQIPSSRAAAP 123
Query: 506 QPP-------PPPPPSSSMASSTPLPWQQ----------NTTTTTTSAGTGSIPPWQQQQ 548
+PP P SS AS LP Q NTT++T + S PP
Sbjct: 124 RPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPP----- 178
Query: 549 AAAAASPGAPQMQGN--PTMVPLPPGVQPPLPPGAPPPPPPPP---PGSAGMMYAPPPPP 603
P P + N PT +P+ P P PP P PG G APPP
Sbjct: 179 ------PPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPP-APPPVK 231
Query: 604 PPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPP 636
PPP P N T P G APPPPP
Sbjct: 232 PPP-SPVNIRT---------GPSGQSLAPPPPP 254
Score = 40.0 bits (92), Expect = 0.007
Identities = 57/237 (24%), Positives = 72/237 (30%), Gaps = 82/237 (34%)
Query: 478 MPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPS-------SSMASSTPLPWQQNTT 530
+PPPPPPP G PPPP Q +QP + T L N
Sbjct: 3 IPPPPPPPPGPPPPPTF-----HQANTEQPKLSRDEQRGRGALLQDICKGTKLKKVTNIN 57
Query: 531 TTT---------TSAGTGSIPPWQQQQAA-----------AAASPGAPQMQGNPTM---- 566
+ +S G GS Q + A G+ + G P +
Sbjct: 58 DRSAPILEKPKGSSGGYGSGGAALQPKGGLFQGGVLKLRPVGAKDGSENLAGKPALQIPS 117
Query: 567 ----VPLPP----------------GVQPPLP----PGAPPPPPPPPPGSAGMMY--APP 600
P PP P LP P P P S GM + + P
Sbjct: 118 SRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAP 177
Query: 601 PPPPPPMDPSNFVTMMGMGVAGMPPFGM------------------PPAPPP--PPP 637
PPPPP + T + M + P + PPAPPP PPP
Sbjct: 178 PPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPP 234
Score = 35.8 bits (81), Expect = 0.12
Identities = 32/111 (28%), Positives = 38/111 (34%), Gaps = 23/111 (20%)
Query: 330 GSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGG 389
G G A P SA P+ +N PPPP+ PP + P P + G
Sbjct: 289 GPVRGLAPPPPTSAS-PSLLSNRPPPPA------RDPPSRGAAPPPPPPV--IRNGARDA 339
Query: 390 PGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWM-----QPPPPPMNQG 435
P P P HG P PPP PPPPP+ G
Sbjct: 340 P---------PPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPLRNG 381
Score = 33.1 bits (74), Expect = 0.81
Identities = 11/15 (73%), Positives = 12/15 (80%)
Query: 576 PLPPGAPPPPPPPPP 590
P+PP PPPP PPPP
Sbjct: 2 PIPPPPPPPPGPPPP 16
Score = 30.8 bits (68), Expect = 4.0
Identities = 12/19 (63%), Positives = 14/19 (73%), Gaps = 2/19 (10%)
Query: 567 VPLPPGVQPPLPPGAPPPP 585
+P+PP PP PPG PPPP
Sbjct: 1 MPIPP--PPPPPPGPPPPP 17
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 99.0 bits (245), Expect = 1e-20
Identities = 91/338 (26%), Positives = 119/338 (35%), Gaps = 42/338 (12%)
Query: 333 SGPATTPLASAP----RPAAPANNPPPPSLMSTTQSRP-------PWMNSGPSESRPYHG 381
+ PA PL+S+P P+A + PP+L +T S P + PS S P
Sbjct: 292 AAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSL 351
Query: 382 MHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQH-NPNGPPPPWMQPPP----PPMNQGP 436
P + P+L H P +P PPP Q PP PP+ P
Sbjct: 352 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP--QAPPALALPPLQAPP 409
Query: 437 HPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPP----MGMMPPPPPPPSGQPPPP 492
PP PP+ +P +H + PPP PP PP P
Sbjct: 410 SPPAS---PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 466
Query: 493 PSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAA 552
PS P Q PP PP S M+ S P Q PP A
Sbjct: 467 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 526
Query: 553 ASPGAPQMQGN-PTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPP-------- 603
P + P P P P+ P A PPP PP +A ++ PP PP
Sbjct: 527 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 586
Query: 604 --PPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPPPQN 639
PP P V+ + +A + P PPPPP ++
Sbjct: 587 RRPPTPGPDTSVSGPRLTLA------LAPGPPPPPSRS 618
Score = 97.4 bits (241), Expect = 3e-20
Identities = 99/347 (28%), Positives = 122/347 (35%), Gaps = 53/347 (15%)
Query: 322 EAPVPASVGSTSGPATTPLASAPR----PAAPANNPPPPSLMSTTQSRPPWMNSGPSESR 377
+ P S+ S++ P ++P S P P APA+ P P RPP + ++
Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAH-PSQPKPKGLQALRPPQVTPPRKDAA 293
Query: 378 PYHGMHGGGP---GGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQ 434
P G P P S P T Q P P PP +
Sbjct: 294 PALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQT 353
Query: 435 GPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPS 494
P PP PP +T +GS L +P PP+ + PPP PP+
Sbjct: 354 LPSPPA---TPPSQ---ATTSLGSPT--LQATHSFLPSPPLSPLATPPPQA------PPA 399
Query: 495 GPLPPWQQQQQQPPPPP--PPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQA--- 549
LPP Q PP PP PP S +A TP P N S PP QA
Sbjct: 400 LALPPLQA----PPSPPASPPLSPLA--TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 453
Query: 550 ----------AAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSA-GMMYA 598
A S P + P VP P PP+ P A PPP PPP +A + A
Sbjct: 454 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 513
Query: 599 PPPPPPPP---MDPSNFVTMMGMGVAGMPPFG------MPPAPPPPP 636
PPP PP P + G PF M P PPP
Sbjct: 514 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 560
Score = 73.9 bits (180), Expect = 4e-13
Identities = 89/314 (28%), Positives = 110/314 (35%), Gaps = 60/314 (19%)
Query: 325 VPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHG 384
+P S PA+ PL+ P+ A N L+ S PP P P+
Sbjct: 402 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP----SPPVQAPF----- 452
Query: 385 GGPGGPGGGPHSFP--HPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHP---- 438
P P P + P PSL P+Q P+ P P M P P Q P P
Sbjct: 453 SPPASPPVSPSATPPSQAPPSLAAP----PLQVPPSPPASPPMSPSATPPPQAPPPLAAP 508
Query: 439 ------PGHHGPP----PMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQ 488
P PP P Q L S P +P P+ PP PP
Sbjct: 509 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 568
Query: 489 P--PPPPSGPLPPWQQQQQQPP--------------------PPPPPSSSMAS--STPLP 524
P PPS P P Q ++PP PPPPPS S +S S P
Sbjct: 569 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL 628
Query: 525 WQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPL----PPG 580
+++ T+T + AAA+ P A +P P PPL PG
Sbjct: 629 AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA--PPLAFRGAPG 686
Query: 581 APPP-PPPPPPGSA 593
AP P PP PGSA
Sbjct: 687 APLPWPPATGPGSA 700
Score = 59.7 bits (143), Expect = 8e-09
Identities = 84/342 (24%), Positives = 106/342 (30%), Gaps = 102/342 (29%)
Query: 294 FQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNP 353
F P P + + SL A + P P+ TP AP P A
Sbjct: 452 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA----A 507
Query: 354 PPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLP-SLTGGHGGHP 412
PP L PP + + P ++ P P SFP P S + P
Sbjct: 508 PPLQLAKPPPQAPPALATPPLQALP-------------SPPASFPGQAPFSPSASLPMSP 554
Query: 413 MQHNPNGPPP----PWMQ-PPPPPMN---QGPHPPGHHGPPPMDQYLGSTPVGSGVYRLH 464
+ P PP P +Q PP PP + Q P P GP T V
Sbjct: 555 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP--------DTSVSG------ 600
Query: 465 QGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPP--------------- 509
P + + P PPPPPS P SGP P
Sbjct: 601 ------PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAA 654
Query: 510 -PPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVP 568
PPP + +A+ P W + G PP A +PGAP +P
Sbjct: 655 ASPPPDAELAACHPAAWSR-----------GPAPP-----LAFRGAPGAP--------LP 690
Query: 569 LPPGVQPPL------------PPGAPPPP----PPPPPGSAG 594
PP P P A P P P P PG++G
Sbjct: 691 WPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSG 732
Score = 59.3 bits (142), Expect = 1e-08
Identities = 86/360 (23%), Positives = 118/360 (32%), Gaps = 73/360 (20%)
Query: 336 ATTPLASAP---RPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGG 392
A TP A AP P P + PPP + T + + + + R GG GG
Sbjct: 14 ARTPAARAPGLLTPRPPGSPRPPPPV---TPAALRVLGAAGAVGRKPLAERAGGIGG-AT 69
Query: 393 GPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWM--QPPPPPMNQGPHP---PGHHGPPPM 447
P S P P+ + G NP PP + PP N P P PG
Sbjct: 70 IPESAPRAGPTRSAGTSSR----NPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125
Query: 448 DQYLGSTPVG-SGVYRLHQGKGMMPP---------------PPMGMMPP----------- 480
LG + S + +GK P P G P
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 185
Query: 481 ----PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSA 536
P P PS +P PP GP + P P++ S Q+ + + +S+
Sbjct: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 537 GTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPP------------ 584
T P + ++ G P+ +P+ P P G+Q PP PP
Sbjct: 246 AT----PLSSPARSGPSARGTPRAPAHPSQ-PKPKGLQALRPPQVTPPRKDAAPALGPLS 300
Query: 585 --PPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPP-----PPPP 637
P P SA + PP P S+ + + PP P APP P PP
Sbjct: 301 SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPP--SPSAPPSLQTLPSPP 358
Score = 34.3 bits (77), Expect = 0.36
Identities = 27/92 (29%), Positives = 34/92 (36%), Gaps = 28/92 (30%)
Query: 571 PGVQPPLPPGAPPPPPPPPP------GSAGMMYAPP-------------PPPPPPMDPSN 611
PG+ P PPG+P PPPP P G+AG + P P P P+
Sbjct: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81
Query: 612 FVTMMGMGVAGMPPFGMPPA----PPPPPPQN 639
G + P PPA PP +N
Sbjct: 82 -----SAGTSSRNPASRPPASGRGERAPPAKN 108
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.134 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,350,075
Number of Sequences: 37866
Number of extensions: 4410795
Number of successful extensions: 147536
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1522
Number of HSP's successfully gapped in prelim test: 2065
Number of HSP's that attempted gapping in prelim test: 24644
Number of HSP's gapped (non-prelim): 40499
length of query: 639
length of database: 18,247,518
effective HSP length: 109
effective length of query: 530
effective length of database: 14,120,124
effective search space: 7483665720
effective search space used: 7483665720
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.