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Search of human proteins with 42518068
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42518068 trans-golgi network protein 2 [Homo sapiens]
(437 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42518068 trans-golgi network protein 2 [Homo sapiens] 863 0.0
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 99 8e-21
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 89 8e-18
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 82 1e-15
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 82 1e-15
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 75 9e-14
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 73 6e-13
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 71 2e-12
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 71 2e-12
gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sap... 70 3e-12
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap... 70 3e-12
gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapi... 70 3e-12
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 69 8e-12
gi|16445033 ACRC protein [Homo sapiens] 68 2e-11
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 65 1e-10
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 65 1e-10
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 64 2e-10
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 64 2e-10
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 63 5e-10
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 63 5e-10
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 63 5e-10
gi|30795231 brain abundant, membrane attached signal protein 1 [... 62 8e-10
gi|109637759 calpastatin isoform f [Homo sapiens] 62 8e-10
gi|157738619 smoothelin-like 1 [Homo sapiens] 62 8e-10
gi|28559039 mediator complex subunit 1 [Homo sapiens] 62 1e-09
gi|161016767 mucin 21 [Homo sapiens] 62 1e-09
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 62 1e-09
gi|150170670 piccolo isoform 2 [Homo sapiens] 62 1e-09
gi|150378539 piccolo isoform 1 [Homo sapiens] 62 1e-09
gi|217330641 IWS1 homolog [Homo sapiens] 61 2e-09
>gi|42518068 trans-golgi network protein 2 [Homo sapiens]
Length = 437
Score = 863 bits (2230), Expect = 0.0
Identities = 437/437 (100%), Positives = 437/437 (100%)
Query: 1 MRFVVALVLLNVAAAGAVPLLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEP 60
MRFVVALVLLNVAAAGAVPLLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEP
Sbjct: 1 MRFVVALVLLNVAAAGAVPLLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEP 60
Query: 61 QTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTK 120
QTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTK
Sbjct: 61 QTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTK 120
Query: 121 DSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPN 180
DSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPN
Sbjct: 121 DSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPN 180
Query: 181 KSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGA 240
KSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGA
Sbjct: 181 KSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGA 240
Query: 241 EEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGE 300
EEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGE
Sbjct: 241 EEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGE 300
Query: 301 ETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLS 360
ETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLS
Sbjct: 301 ETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLS 360
Query: 361 DSTGSEKDDLYPNGSGNGSAESSHFFAYLVTAAILVAVLYIAHHNKRKIIAFVLEGKRSK 420
DSTGSEKDDLYPNGSGNGSAESSHFFAYLVTAAILVAVLYIAHHNKRKIIAFVLEGKRSK
Sbjct: 361 DSTGSEKDDLYPNGSGNGSAESSHFFAYLVTAAILVAVLYIAHHNKRKIIAFVLEGKRSK 420
Query: 421 VTRRPKASDYQRLDQKS 437
VTRRPKASDYQRLDQKS
Sbjct: 421 VTRRPKASDYQRLDQKS 437
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 99.0 bits (245), Expect = 8e-21
Identities = 83/333 (24%), Positives = 156/333 (46%), Gaps = 16/333 (4%)
Query: 24 ESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPN- 82
+S +EEA P A + + S KS + ++P +KS AEA++PE +
Sbjct: 551 KSPAKEEAKSPPEAKSPEKEEAKSP---AEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP 607
Query: 83 -----KSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDST 137
KS AEAK+ KS AE K+ + + S + EA++ + + S E ++P+ +
Sbjct: 608 VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAK 667
Query: 138 GKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSG 197
AEA++PE + + AEAK+ + + S EA++ + + + ++P+ S
Sbjct: 668 SPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVK 727
Query: 198 AEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQ- 256
E +TP+ + E ++P+ + A+ +K+ A+E+ SP PE+
Sbjct: 728 EEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEAR--SPADKFPEKA 785
Query: 257 --PSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQ--EEV 312
P +++ P S KE KA ++ K ++ + E +E + PP+ EE
Sbjct: 786 KSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845
Query: 313 KSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEK 345
K+ + E K+++ ++ +E PK E++K
Sbjct: 846 KAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKK 878
Score = 95.5 bits (236), Expect = 8e-20
Identities = 83/321 (25%), Positives = 141/321 (43%), Gaps = 30/321 (9%)
Query: 24 ESVKQEEAGVRPSA--GNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTP 81
E K+EE G A G T ++ K E ++P +KS AEA++PE
Sbjct: 481 EEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEK---EAKSPVKEEAKSPAEAKSPEKEE 537
Query: 82 NKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSG 141
KS AE K+ + + + + EA KS PE ++P+ KS
Sbjct: 538 AKSPAEVKSPEKAKSPAKEEA----------------------KSPPEAKSPEKEEAKSP 575
Query: 142 AEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQ 201
AE ++PE + + + EAK+ + +KS +A++ KS A+ ++P +KS AE +
Sbjct: 576 AEVKSPEKAKSPAKEEAKSPAE--AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVK 633
Query: 202 TPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKD 261
+P+ + + E ++P+ + E + P S AE ++ + + + V E S +
Sbjct: 634 SPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEK 693
Query: 262 HSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDV 321
P+ + + E K+ + A + + K E+ SP +EE KS E +
Sbjct: 694 AKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSP 753
Query: 322 EPKEAEDDDTGPEEGSPPKEE 342
E K D PE +P KEE
Sbjct: 754 E-KAKTLDVKSPEAKTPAKEE 773
Score = 91.7 bits (226), Expect = 1e-18
Identities = 90/335 (26%), Positives = 153/335 (45%), Gaps = 33/335 (9%)
Query: 28 QEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPN----- 82
+EE P+ S KS E ++P+ +KS AE ++PE +
Sbjct: 498 EEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 557
Query: 83 -KSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSG 141
KS EAK+ + KS AE K+ + + S + EA++ ++ KS + ++P KS
Sbjct: 558 AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEA--KSPEKAKSPVKEEAKSP 615
Query: 142 AEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQ 201
AEA++P +S AE K+ + + S + EA++ + + + ++P+ S AE +
Sbjct: 616 AEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAK 675
Query: 202 TPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKD 261
+P+ + AE ++P+ KS +E+ +KS +E+ SP K + P +++
Sbjct: 676 SPEKAKSPVKAEAKSPEKA--KSPVKEEAKSPEKAKSPVKEEAK--SPEKA--KSPVKEE 729
Query: 262 HSKPISNPSDNKELPKA-DTNQLADKGKL----SPHAFKTESGEET---------DLISP 307
P S KE K+ + + +K K SP A KT + EE SP
Sbjct: 730 AKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEA-KTPAKEEARSPADKFPEKAKSP 788
Query: 308 PQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEE 342
+EEVKS E + ++D PE+ P KEE
Sbjct: 789 VKEEVKSPEKAK----SPLKEDAKAPEKEIPKKEE 819
Score = 87.4 bits (215), Expect = 2e-17
Identities = 83/326 (25%), Positives = 138/326 (42%), Gaps = 38/326 (11%)
Query: 59 EPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQT 118
E ++P+ + S EA++PE + EAK+ + + + EAKT + + S EA++
Sbjct: 687 EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKS 746
Query: 119 TKDSTSKSHPELQTPKDSTGKSGA--EAQTPEDS-PNRSGAEAKTQKDSPSKSGSEAQTT 175
+ + S + K K+ A EA++P D P ++ + K + SP K+ S +
Sbjct: 747 PEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKED 806
Query: 176 KDVPNKSGADGQTPKDGSSKSGA-EDQTPKDV-----PNKSGAEKQ--TPKDGSNKSGAE 227
P K + PK KS E++ P++V P K+ EK TPK K +
Sbjct: 807 AKAPEK-----EIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKK 861
Query: 228 EQGP----------------IDGPSKSGAEEQTSKDSPNKVVP---EQPSRKDHSKPISN 268
E+ P ++ P +S E + + K VP ++ K K +
Sbjct: 862 EEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAK 921
Query: 269 PSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAED 328
P + E+ K + + K P K + E+ D +E+ K E E K ED
Sbjct: 922 PKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDT---KEEKAKKPEEKPKTEAKAKED 978
Query: 329 DDTGPEEGSPPKEEKEKMSGSASSEN 354
D T +E S PK EK + S S ++
Sbjct: 979 DKTLSKEPSKPKAEKAEKSSSTDQKD 1004
Score = 85.9 bits (211), Expect = 7e-17
Identities = 81/326 (24%), Positives = 140/326 (42%), Gaps = 28/326 (8%)
Query: 35 PSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDS 94
P +VSTH + E +T + + E Q E+ + EAK ++
Sbjct: 427 PKIPSVSTHIKVKSEEKIKVVEKSEKETV--IVEEQTEETQVTEEVTEEEEKEAKEEEGK 484
Query: 95 SNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRS 154
+ G E + + G A+ + E ++P KS AEA++PE +S
Sbjct: 485 EEEGGEEEEAEGGEEETKSPPAE----EAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKS 540
Query: 155 GAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSS----KSGAEDQTPKDVPNKS 210
AE K+ + + S + EA++ + + + ++P + S KS A+++ KS
Sbjct: 541 PAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKS 600
Query: 211 GAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPS 270
+ ++P KS AE + P+ +KS AE + SP K + P++++ P S
Sbjct: 601 PEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVK----SPEKA--KSPTKEEAKSPEKAKS 654
Query: 271 DNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDD 330
KE K+ +K K SP + +S E+ SP + E KS E + +EA+
Sbjct: 655 PEKEEAKSP-----EKAK-SPVKAEAKSPEKAK--SPVKAEAKSPEKAKSPVKEEAK--- 703
Query: 331 TGPEEGSPPKEEKEKMSGSASSENRE 356
PE+ P +E+ K A S +E
Sbjct: 704 -SPEKAKSPVKEEAKSPEKAKSPVKE 728
Score = 84.0 bits (206), Expect = 3e-16
Identities = 90/365 (24%), Positives = 157/365 (43%), Gaps = 52/365 (14%)
Query: 59 EPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQT 118
E ++P+ + S EA++PE + AEAK+ + + + AEAK+ + + S EA++
Sbjct: 645 EAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKS 704
Query: 119 TKDSTSKSHPELQTPKDSTGKSGAEAQTPED--SPNRSGAEAKTQKDSPSKSGS------ 170
+ + S E ++P+ + EA+TPE SP + A++ + SP K+ +
Sbjct: 705 PEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSP 764
Query: 171 EAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDV--PNKSGA---EKQTPKDGSNKSG 225
EA+T +S AD + P+ S E ++P+ P K A EK+ PK KS
Sbjct: 765 EAKTPAKEEARSPAD-KFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP 823
Query: 226 A-EEQGP----IDGPSKSGAEEQT-------------SKDSPNKVVPEQPSRKDHSKPIS 267
EE+ P + P K EE+ +++P K P+ + +
Sbjct: 824 VKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE 883
Query: 268 NPSDNKELPKA----DTNQLADKGKLSPHAFKTESG----EETDLISPPQEEVKSSEPTE 319
P ++K K D ++ K +P + + E+T++ ++ K+ EP++
Sbjct: 884 KPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK 943
Query: 320 DVEPKEA--EDDDTGPEEGSPP----------KEEKEKMSGSASSENREGTLSDSTGSEK 367
E KEA E DT E+ P KE+ + +S S E S+ +K
Sbjct: 944 PAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQK 1003
Query: 368 DDLYP 372
D P
Sbjct: 1004 DSKPP 1008
Score = 45.1 bits (105), Expect = 1e-04
Identities = 55/230 (23%), Positives = 91/230 (39%), Gaps = 36/230 (15%)
Query: 143 EAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQT---PKDGSSKSGAE 199
E Q E+ EAK ++ + G E + G + +T P + ++ E
Sbjct: 463 ETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEA-------EGGEEETKSPPAEEAASPEKE 515
Query: 200 DQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSR 259
++P KS AE ++P+ KS AE + P +KS A+E+ +K P PE+
Sbjct: 516 AKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSP--EKAKSPAKEE-AKSPPEAKSPEKEEA 572
Query: 260 KDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTE 319
K ++ + +P K K + A+ SP K SP +EE KS P E
Sbjct: 573 KSPAE-VKSPEKAKSPAKEEAKSPAEAK--SPEKAK----------SPVKEEAKS--PAE 617
Query: 320 DVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDD 369
P + EE P E K + ++ + + EK++
Sbjct: 618 AKSPVK--------EEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEE 659
Score = 40.8 bits (94), Expect = 0.002
Identities = 34/144 (23%), Positives = 57/144 (39%), Gaps = 7/144 (4%)
Query: 49 RPGGSTKSHPEPQTPKDSP---SKSSAEAQTPEDTPNKSG-AEAKTQKDSSNKSGAEAKT 104
+P K P + PK+S K AE + TP K A+ + ++D+ K E
Sbjct: 871 KPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAK 930
Query: 105 QKGSTSKS---GSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQ 161
++ +K+ A+ + + K + + K K EA+ ED S +K +
Sbjct: 931 KEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPK 990
Query: 162 KDSPSKSGSEAQTTKDVPNKSGAD 185
+ KS S Q P K+ D
Sbjct: 991 AEKAEKSSSTDQKDSKPPEKATED 1014
Score = 38.5 bits (88), Expect = 0.012
Identities = 39/179 (21%), Positives = 68/179 (37%), Gaps = 40/179 (22%)
Query: 199 EDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPS 258
E+QT + + E++ K+ + G EE+G + ++ G EE S + PE+ +
Sbjct: 458 EEQTEETQVTEEVTEEEE-KEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEA 516
Query: 259 RKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPT 318
+ + +P++ K SP +EE KS P
Sbjct: 517 KSPVKEEAKSPAEAK--------------------------------SPEKEEAKS--PA 542
Query: 319 EDVEPKEA-----EDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYP 372
E P++A E+ + PE SP KEE + + S E + + S + P
Sbjct: 543 EVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSP 601
Score = 29.3 bits (64), Expect = 7.4
Identities = 24/108 (22%), Positives = 44/108 (40%), Gaps = 7/108 (6%)
Query: 265 PISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPK 324
P S P ++P T+ + K+E +ET ++ EE + +E + E K
Sbjct: 419 PFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSE--KETVIVEEQTEETQVTEEVTEEEEK 476
Query: 325 EAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYP 372
EA+ EEG + +E+ + E + ++ EK+ P
Sbjct: 477 EAK-----EEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSP 519
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 89.0 bits (219), Expect = 8e-18
Identities = 72/344 (20%), Positives = 137/344 (39%), Gaps = 7/344 (2%)
Query: 41 STHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKS-G 99
S++ S S S S + DS S+++ + + + + +++ DSS+ S
Sbjct: 557 SSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS 616
Query: 100 AEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAK 159
+++ K +SKS S++ DS SKS DS+ S + + + + S +
Sbjct: 617 SDSSDSKSDSSKSESDSS---DSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSD 673
Query: 160 TQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKD 219
+ S S S + + D + S + + SS S + D + N S ++ D
Sbjct: 674 SSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSD 733
Query: 220 GSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSD-NKELPKA 278
S+ S + + S + ++ S DS N S S SN SD N +
Sbjct: 734 SSDSSNSSDSSD-SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792
Query: 279 DTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSP 338
D++ ++ S + ++S + +D S + +S + D D + +GS
Sbjct: 793 DSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS- 851
Query: 339 PKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAES 382
+ + S SS++ + + S ++ D N S N S S
Sbjct: 852 DSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSS 895
Score = 89.0 bits (219), Expect = 8e-18
Identities = 65/364 (17%), Positives = 139/364 (38%), Gaps = 10/364 (2%)
Query: 22 ATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTP 81
+++S ++ + + + S S+ + S + S S ++++ ++
Sbjct: 604 SSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSS 663
Query: 82 NKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSG 141
N S + + S+ S + + S S S + + DS+ S + DS+ +
Sbjct: 664 NSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNS 723
Query: 142 AEAQTPEDSPNRSGAEAKTQKDSPSKS-GSEAQTTKDVPNKSGADGQTPKDGSSKSGAED 200
+++ + S + + + DS S S++ + D N S + + SS S
Sbjct: 724 SDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 783
Query: 201 QTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRK 260
+ + ++ D SN S + D S ++ S DS N S
Sbjct: 784 DSNDSSNSSDSSDSSNSSDSSNSSDSS-----DSSDSSDSDSSNSSDSSNS---SDSSDS 835
Query: 261 DHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTED 320
+S S+ SD+ + +D++ +D S + ++S +D S + +SS ++
Sbjct: 836 SNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSD-SSDSSDSNESSNSSDS 894
Query: 321 VEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSA 380
+ + D D+ S + S S+ S N + S S D + + S+
Sbjct: 895 SDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS 954
Query: 381 ESSH 384
+SS+
Sbjct: 955 DSSN 958
Score = 89.0 bits (219), Expect = 8e-18
Identities = 62/346 (17%), Positives = 134/346 (38%), Gaps = 3/346 (0%)
Query: 41 STHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGA 100
S+ S S S+ S + S S S+ + D+ + S +++ DSSN + +
Sbjct: 665 SSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSS 724
Query: 101 EAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKT 160
++ + S S S + + DS+ S+ + + S + + + S + + +
Sbjct: 725 DSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 784
Query: 161 QKDSPSKS-GSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKD 219
DS + S S++ + D N S + + S S + D + + S +
Sbjct: 785 SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS 844
Query: 220 GSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKAD 279
+ G++ S + ++ S DS N S + S S+ SD+ +D
Sbjct: 845 SDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSD 904
Query: 280 TNQLADKGKLSPHAFKTESGEETDLI--SPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGS 337
++ ++ S + ++S E ++ S + SS+ ++ + + D + +
Sbjct: 905 SSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSN 964
Query: 338 PPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAESS 383
S S+ S N + S S+ D + + + S++SS
Sbjct: 965 SSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1010
Score = 85.5 bits (210), Expect = 9e-17
Identities = 76/352 (21%), Positives = 139/352 (39%), Gaps = 24/352 (6%)
Query: 41 STHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKS-GAEAKTQKDSSNKS- 98
S++ S S S+ S + S S S+ + D+ N S +++ DSSN S
Sbjct: 749 SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808
Query: 99 GAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEA 158
+++ S S + S++ + DS+ S+ DS+ S + + DS NRS
Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS-----DSSDSSDSSDGSDSDSSNRS---- 859
Query: 159 KTQKDSPSKSGSEAQTTKDVPNKSGA-DGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTP 217
+ S S S++ + D + S + + D S S + D D N S + +
Sbjct: 860 DSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSN 919
Query: 218 KDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPK 277
S++S S + ++ S DS N S +S SN SD+ +
Sbjct: 920 SSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNS------SDSSNSSDSSNSSDSSDSNS 973
Query: 278 ADTNQLADKGKLSPHAFKTESGEETDL--ISPPQEEVKSSEPTEDVEPKEAED----DDT 331
+D++ ++ S + ++S + +D S + SS+ + + + D D+
Sbjct: 974 SDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS 1033
Query: 332 GPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAESS 383
S + S S+ S N + S S+ D + + S+ESS
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESS 1085
Score = 85.1 bits (209), Expect = 1e-16
Identities = 68/349 (19%), Positives = 143/349 (40%), Gaps = 15/349 (4%)
Query: 41 STHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGA 100
S++ S S S+ S + S S S+++ D+ + S + +S+ S
Sbjct: 737 SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSD 796
Query: 101 EAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKT 160
+ + S S S++ + DS S + + DS+ S + + + + S + G+++ +
Sbjct: 797 SSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS-SDSSDSSDSSDGSDSDS 855
Query: 161 QKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSG--AEDQTPKDVPNKSGAEKQTPK 218
S S + S++ + D N S + + + SS S ++ D + +
Sbjct: 856 SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSS 915
Query: 219 DGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKA 278
D SN S + E S + ++ S DS N S +S SN SD+ +
Sbjct: 916 DSSNSSDSSE-------SSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDS 968
Query: 279 DTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAED--DDTGPEEG 336
+ +D S + ++S + +D S + SS+ ++ + ++ + D + +
Sbjct: 969 SDSNSSDSSDSSNSSDSSDSSDSSD-SSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDS 1027
Query: 337 SPPKEEKEKMSGSASSENREGTLS--DSTGSEKDDLYPNGSGNGSAESS 383
S + + S SS++ + + S S S+ D + + S++SS
Sbjct: 1028 SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1076
Score = 85.1 bits (209), Expect = 1e-16
Identities = 70/355 (19%), Positives = 145/355 (40%), Gaps = 22/355 (6%)
Query: 41 STHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGA 100
S++ S S S+ S + S S S+++ D+ + + +++ DSS+ S +
Sbjct: 779 SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS 838
Query: 101 EAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGA--EAQTPEDSPNRSGAEA 158
+ + S S GS++ ++ S S + + DS+ S + + + E S + +++
Sbjct: 839 -SDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDS 897
Query: 159 KTQKDSPSKSGSEAQTTKDVPNKS-------GADGQTPKDGSSKSGAEDQTPKDVPNKSG 211
DS S S + + D N S +D D S+ S + D + + +
Sbjct: 898 SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSS----DSSNS 953
Query: 212 AEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQT-SKDSPNKVVPEQPSRKDHSKPISNPS 270
++ D SN S + + D S + + + S DS + S S S+ S
Sbjct: 954 SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013
Query: 271 DNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAED-D 329
D+ +D++ +D S + ++S + +D + SS+ + + ++ D
Sbjct: 1014 DSSN--SSDSSNSSDSSNSSDSSDSSDSSDSSD----SSDSSDSSDSSNSSDSSDSSDSS 1067
Query: 330 DTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAESSH 384
D+ S + + S S+ S N + S S+ D + + S++SS+
Sbjct: 1068 DSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1122
Score = 85.1 bits (209), Expect = 1e-16
Identities = 74/361 (20%), Positives = 140/361 (38%), Gaps = 20/361 (5%)
Query: 37 AGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKS-SAEAQTPEDTPNKSGAEAKTQKDSS 95
+ N S + S S S + DS + S S+++ D+ + S + + DSS
Sbjct: 797 SSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS 856
Query: 96 NKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSG 155
N+S + + +S S + + ++ S S E DS+ S + DS N S
Sbjct: 857 NRSDSSNSSDSSDSSDSSNSSDSSDSSDSN---ESSNSSDSSDSSNSSDSDSSDSSNSSD 913
Query: 156 AEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQ 215
+ + S+S + + + + + +D D S+ S + + + D N S +
Sbjct: 914 SSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS--DSSNSSDSSDS 971
Query: 216 TPKDGSNKSGAEEQGPIDGPSKS-----------GAEEQTSKDSPNKVVPEQPSRKDHSK 264
D S+ S + + S S ++ S DS N S +S
Sbjct: 972 NSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSS 1031
Query: 265 PISNPSDNKE-LPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEP 323
S+ SD+ + +D++ +D S + ++S + +D S + SSE ++ +
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD-SSDSSDSSDSSESSDSSDS 1090
Query: 324 KEAED-DDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAES 382
+ D D+ S + S S+ S N + S S+ D + + S+ES
Sbjct: 1091 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSES 1150
Query: 383 S 383
S
Sbjct: 1151 S 1151
Score = 83.6 bits (205), Expect = 3e-16
Identities = 56/326 (17%), Positives = 131/326 (40%), Gaps = 4/326 (1%)
Query: 59 EPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQT 118
+P + +S A +++ ++ ++ A + + N +G+++K + S S S+
Sbjct: 464 DPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNN 523
Query: 119 TKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDV 178
+ + + ++ K +GK +++ + S + + +++ DS S S S + + D
Sbjct: 524 SDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDS-SDSNSSSDSDS 582
Query: 179 PNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKS 238
+ +D S + ++ D + S + + D + S E D SKS
Sbjct: 583 SDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSS--DSKSDSSKSESDSSDSDSKS 640
Query: 239 GAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKE-LPKADTNQLADKGKLSPHAFKTE 297
+ + S DS + S +S S+ SD+ + +D++ +D S + +E
Sbjct: 641 DSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSE 700
Query: 298 SGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREG 357
S + +D + S + + + D+ S + S S+ S +
Sbjct: 701 SSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD 760
Query: 358 TLSDSTGSEKDDLYPNGSGNGSAESS 383
+ + S S+ D + + S++S+
Sbjct: 761 SSNSSDSSDSSDSSDSSDSSNSSDSN 786
Score = 82.8 bits (203), Expect = 6e-16
Identities = 69/354 (19%), Positives = 137/354 (38%), Gaps = 9/354 (2%)
Query: 36 SAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKS-GAEAKTQKDS 94
S+ + + S ++ + DS S S+ + D+ N S +E+ D+
Sbjct: 873 SSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN 932
Query: 95 SNKSGAE--AKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKS-GAEAQTPEDSP 151
SN S + + + S S + S++ + DS++ S DS+ S +++ DS
Sbjct: 933 SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992
Query: 152 NRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQT-PKDVPNKS 210
+ S + + S S + ++ + + +D D S S + D + D + S
Sbjct: 993 DSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052
Query: 211 GAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPS 270
+ + S+ S S +E S DS N S S S+ S
Sbjct: 1053 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1112
Query: 271 DNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAED-D 329
D+ + +D++ +D S + ++S +D S E SS+ ++ + ++ D
Sbjct: 1113 DSSD--SSDSSNSSDSSDSSDSSDSSDSSNSSD-SSDSSESSDSSDSSDSSDSSDSSDSS 1169
Query: 330 DTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAESS 383
D+ S + S S+ S + + S S+ D + + S++SS
Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1223
Score = 82.8 bits (203), Expect = 6e-16
Identities = 70/362 (19%), Positives = 138/362 (38%), Gaps = 11/362 (3%)
Query: 22 ATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTP 81
+++S ++ + N S + S S S DS S SS + + + +
Sbjct: 935 SSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDS-SNSSDSSDSSDSSD 993
Query: 82 NKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSG 141
+ +++ DSS+ S + + +S S + ++ S S + DS+ S
Sbjct: 994 SSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1053
Query: 142 AEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQ 201
+ + + S + + S S SE+ + D N S + + SS S
Sbjct: 1054 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1113
Query: 202 TPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKD 261
+ + + ++ D S+ S + S+S ++ S DS + S
Sbjct: 1114 SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSES-SDSSDSSDSSDSSDSSDSSDSS 1172
Query: 262 HSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDV 321
S SN SD+ + +D++ +D S + ++S + +D S + SS+ ++
Sbjct: 1173 DSSDSSNSSDSSD--SSDSSDSSDSSDSSDSSDSSDSSDSSDS-SDSSDSSDSSDSSDSS 1229
Query: 322 EPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAE 381
+ E+ D S + S S+ S + + SDS E D +G+GN +
Sbjct: 1230 DSNESSDSSD-----SSDSSDSSNSSDSSDSSDSSDSTSDSN-DESDSQSKSGNGNNNGS 1283
Query: 382 SS 383
S
Sbjct: 1284 DS 1285
Score = 81.3 bits (199), Expect = 2e-15
Identities = 72/339 (21%), Positives = 130/339 (38%), Gaps = 11/339 (3%)
Query: 36 SAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSS 95
S N S S S S + S SS + + + + + + +++ DSS
Sbjct: 969 SDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSS 1028
Query: 96 NKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSG 155
N S + + +S S + ++ S S + DS+ S + + + S
Sbjct: 1029 NSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS 1088
Query: 156 AEAKTQKDSPSKSGSEAQTTKDVPNKS-GADGQTPKDGSSKSGAEDQTPKDVPNKSG--A 212
+ + S S S++ + D + S +D D S S + D + + S +
Sbjct: 1089 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSS 1148
Query: 213 EKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDN 272
E D S+ S + + S S ++ S DS + S S S+ SD+
Sbjct: 1149 ESSDSSDSSDSSDSSDSSDSSDSSDS-SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1207
Query: 273 KELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDD--D 330
+ +D++ +D S + ++S E +D S + SS ++ + ++ D D
Sbjct: 1208 SD--SSDSSDSSDSSDSSDSSDSSDSNESSDS-SDSSDSSDSSNSSDSSDSSDSSDSTSD 1264
Query: 331 TGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDD 369
+ E S K +GS S + EG SDS S DD
Sbjct: 1265 SNDESDSQSKSGNGNNNGSDSDSDSEG--SDSNHSTSDD 1301
Score = 80.1 bits (196), Expect = 4e-15
Identities = 76/360 (21%), Positives = 132/360 (36%), Gaps = 31/360 (8%)
Query: 36 SAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKS-GAEAKTQKDS 94
S + S+ S S S S+ S S S+++ D+ + S + + DS
Sbjct: 699 SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758
Query: 95 SNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRS 154
S+ S + S S S++ + DS++ S + S +++ DS N S
Sbjct: 759 SDSSNS-------SDSSDSSDSSDSSDSSNSS----DSNDSSNSSDSSDSSNSSDSSNSS 807
Query: 155 GAEAKTQKDSPSKSGSEAQTTKDVPNKS-GADGQTPKDGSSKSGAEDQTPKDVPNKS--- 210
+ DS S S++ + D N S +D D S S + D + D N+S
Sbjct: 808 DS-----SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSS 862
Query: 211 -GAEKQTPKDGSNKSGA-------EEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDH 262
++ D SN S + E D S + + S DS N S
Sbjct: 863 NSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSD 922
Query: 263 SKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVE 322
S SN SDN +D++ +D S + ++S +D + +S + D
Sbjct: 923 SSESSNSSDNSN--SSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS 980
Query: 323 PKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAES 382
D + + S + S SS++ + + S + + D + S + S S
Sbjct: 981 NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040
Score = 79.3 bits (194), Expect = 6e-15
Identities = 69/349 (19%), Positives = 136/349 (38%), Gaps = 24/349 (6%)
Query: 36 SAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKS-GAEAKTQKDS 94
S+ + + S S S+ S + S S S+++ D+ + S +++ DS
Sbjct: 962 SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021
Query: 95 SNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRS 154
SN S + + + S S S++ + DS+ S + + S + + + S +
Sbjct: 1022 SNSSDS-SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080
Query: 155 GAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEK 214
+E+ DS S S + ++ + +D D S S + D + ++
Sbjct: 1081 SSESSDSSDS-SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD-------SSDSSDS 1132
Query: 215 QTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKE 274
D SN S + + S ++ S DS + S S SN SD+ +
Sbjct: 1133 SDSSDSSNSSDSSD-------SSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1185
Query: 275 LPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPE 334
+D++ +D S + ++S + +D S + SS+ ++ + E+ D
Sbjct: 1186 --SSDSSDSSDSSDSSDSSDSSDSSDSSD-SSDSSDSSDSSDSSDSSDSNESSDS----S 1238
Query: 335 EGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAESS 383
+ S + S SS++ + T + S+ NG+ NGS S
Sbjct: 1239 DSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDS 1287
Score = 78.6 bits (192), Expect = 1e-14
Identities = 69/359 (19%), Positives = 139/359 (38%), Gaps = 28/359 (7%)
Query: 36 SAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSS 95
S G+ S + S+ G + S + +D S S+++ + N + K S
Sbjct: 487 SRGDASYNSDESKDNGNGSDS----KGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDS 542
Query: 96 NKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSG 155
K +++ S S + S++ + DS S S + DS+ +++ + S + +
Sbjct: 543 GKGKSDSSDSDSSDSSNSSDSSDSSDSDS-SDSNSSSDSDSSDSDSSDSSDSDSSDSSNS 601
Query: 156 AEAKTQKDSPSKS-GSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEK 214
+++ DS S S++ +K +KS +D D SKS + D D + S +
Sbjct: 602 SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSS---DSDSKSDSSDSNSSDSSDNSDSS- 657
Query: 215 QTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKE 274
D SN S + + S ++ +S DS N S +S S+ SD+ +
Sbjct: 658 ----DSSNSSNSSDSSD----SSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSD 709
Query: 275 LPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKE--------- 325
+D++ ++ + + ++ S + SS ++ + +
Sbjct: 710 SDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSD 769
Query: 326 -AEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAESS 383
++ D+ S + S S+ S N + + S S+ D + S N S S+
Sbjct: 770 SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN 828
Score = 75.1 bits (183), Expect = 1e-13
Identities = 64/316 (20%), Positives = 123/316 (38%), Gaps = 16/316 (5%)
Query: 79 DTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTG 138
D+ + +++ DSS+ S +++ + S+S S S + DS+ + DS+
Sbjct: 548 DSSDSDSSDSSNSSDSSDSSDSDS-SDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSD 606
Query: 139 KS----GAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSS 194
S +++ DS + S DS SKS S + D + S + + SS
Sbjct: 607 SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666
Query: 195 KSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVP 254
S + + + D S+ S + E D S ++ S DS N
Sbjct: 667 DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESS--DSSDSSDSDSSDSSDSSNSNSS 724
Query: 255 E-QPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVK 313
+ S S SN SD+ + +D++ +D S + ++S + +D S +
Sbjct: 725 DSDSSNSSDSSDSSNSSDSSD--SSDSSNSSDSSDSSDSSNSSDSSDSSD-SSDSSDSSN 781
Query: 314 SSEPTEDVEPKEAED-----DDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKD 368
SS+ + ++ D D + + S + + S ++S + SDS+ S
Sbjct: 782 SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841
Query: 369 DLYPNGSGNGSAESSH 384
+ S ++SS+
Sbjct: 842 SDSSDSSDGSDSDSSN 857
Score = 63.5 bits (153), Expect = 4e-10
Identities = 83/363 (22%), Positives = 136/363 (37%), Gaps = 37/363 (10%)
Query: 38 GNVST-HPSLSQRPGGSTKSHPEPQTPKD--------SPSKSSAEAQTPEDTPNKSGAEA 88
GN S P ++ + G+ ++ P T +D SPS + A+ E + + EA
Sbjct: 208 GNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEA 267
Query: 89 KTQKDSSNKSGAEAKTQKG------STSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGA 142
KDSSN S + G S+ S+++ D K P + D T KS
Sbjct: 268 GNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEE 327
Query: 143 -EAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSK-SGAED 200
A PED N S TQK + +S K V N+ + +T G S+ G E
Sbjct: 328 NSAGIPED--NGSQRIEDTQKLNHRES-------KRVENRITKESETHAVGKSQDKGIEI 378
Query: 201 QTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRK 260
+ P SG T + G G E++G G +T + N P Q S
Sbjct: 379 KGP-----SSGNRNITKEVGKGNEGKEDKGQ-HGMILGKGNVKTQGEVVNIEGPGQKSEP 432
Query: 261 DHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTED 320
+ SN + D+ DK ++ D + + SS
Sbjct: 433 GNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDAS 492
Query: 321 VEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSA 380
E++D+ G + ++ + S + +S++ + + ++K D SG G +
Sbjct: 493 YNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSD-----SGKGKS 547
Query: 381 ESS 383
+SS
Sbjct: 548 DSS 550
Score = 56.6 bits (135), Expect = 4e-08
Identities = 84/379 (22%), Positives = 143/379 (37%), Gaps = 53/379 (13%)
Query: 36 SAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSS 95
+A + S+ G + +S+ T K++ + +A ED A Q+D
Sbjct: 132 TANGIQGQVSIIDNAGATNRSNTNGNTDKNTQNGDVGDAGHNEDV-------AVVQEDGP 184
Query: 96 NKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPED------ 149
+G+ T S + +TS+ P++ + ++ T ++ T ED
Sbjct: 185 QVAGSNNSTDNEDEIIENS--CRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNS 242
Query: 150 --SPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKS-GADGQT--PKDGSSKSGAEDQTPK 204
SP+ +GA+ + S EA KD N S G +GQ +D S ++ K
Sbjct: 243 DGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSK 302
Query: 205 DVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAE---------EQTSKDSPNKVVPE 255
+ + G E + +K+ E+ P +G++ + SK N++ E
Sbjct: 303 EYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKE 362
Query: 256 QPSR-----KDHSKPISNPSD-----NKELPKADTNQLADKGK----LSPHAFKTESGEE 301
+ +D I PS KE+ K + + DKG+ L KT+ GE
Sbjct: 363 SETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGK-EDKGQHGMILGKGNVKTQ-GEV 420
Query: 302 TDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSD 361
++ P Q+ SEP V D S ++K M G + + E +D
Sbjct: 421 VNIEGPGQK----SEPGNKVGHSNTGSDSNSDGYDSYDFDDK-SMQGDDPNSSDESNGND 475
Query: 362 STGSEKDDLYPNGSGNGSA 380
SE D+ N S G A
Sbjct: 476 DANSESDN---NSSSRGDA 491
Score = 36.2 bits (82), Expect = 0.060
Identities = 21/136 (15%), Positives = 55/136 (40%)
Query: 22 ATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTP 81
+++S ++ ++ + S S S S + S SS + + + +
Sbjct: 1165 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1224
Query: 82 NKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSG 141
+ +++ DSS+ S + + +S S + +T DS +S + ++ + S
Sbjct: 1225 SSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSD 1284
Query: 142 AEAQTPEDSPNRSGAE 157
+++ + N S ++
Sbjct: 1285 SDSDSEGSDSNHSTSD 1300
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 81.6 bits (200), Expect = 1e-15
Identities = 87/340 (25%), Positives = 135/340 (39%), Gaps = 37/340 (10%)
Query: 55 KSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGS 114
+ PE + + + KS +A PE E + +K+ E + +G+ S
Sbjct: 496 EEEPEAEEEEVAAKKSPVKATAPEVK------EEEGEKEEEEGQEEEEEEDEGAKSDQAE 549
Query: 115 EAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQT 174
E + K+ +S E + + G++ AEA+ E AEAK +K KS A
Sbjct: 550 EGGSEKEGSS----EKEEGEQEEGETEAEAEGEE-------AEAKEEKKVEEKSEEVATK 598
Query: 175 TKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDG 234
+ V + + K KS E++ VP EK K KS EE+G
Sbjct: 599 EELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEK--GKSPVPKSPVEEKGKSPV 656
Query: 235 P------------SKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQ 282
P SKS EE+ P V E S+ + K + KE+ +A +
Sbjct: 657 PKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEE 716
Query: 283 LADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEE 342
+K + P + E+ SP +EE + T K + +T EEG P ++E
Sbjct: 717 KVEKKEEKP----KDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKET-KEEGKPLQQE 771
Query: 343 KEK-MSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAE 381
KEK +G EG+ + GS K+D+ NG G E
Sbjct: 772 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEE 811
Score = 51.6 bits (122), Expect = 1e-06
Identities = 80/345 (23%), Positives = 130/345 (37%), Gaps = 43/345 (12%)
Query: 24 ESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNK 83
E K ++A S S+ ++ G T++ E + + K E T +
Sbjct: 541 EGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEE 600
Query: 84 SGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAE 143
A+AK +K KS K + G P ++P + GKS
Sbjct: 601 LVADAKVEKPEKAKS----PVPKSPVEEKGKS------------PVPKSPVEEKGKSPVP 644
Query: 144 AQTPED---SPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAED 200
E+ SP + K SKS E + VP KS + K K ++
Sbjct: 645 KSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVP-KSPVEEAKSKAEVGKGEQKE 703
Query: 201 QTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRK 260
+ K+V K+ PK+ K +E+ P D P K AE +++ +VV S K
Sbjct: 704 EEEKEV-------KEAPKE--EKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVK 754
Query: 261 DHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTED 320
H + + KE K Q +K K E G + +E++ + +
Sbjct: 755 VHLE-----KETKEEGK-PLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVN---GE 805
Query: 321 VEPKEAEDDDTGPEEGSPPKEEKEKMSG----SASSENREGTLSD 361
VE KE + +T E+GS +EEK ++ S + E + G S+
Sbjct: 806 VEGKEEVEQET-KEKGSGREEEKGVVTNGLDLSPADEKKGGDKSE 849
Score = 35.4 bits (80), Expect = 0.10
Identities = 36/150 (24%), Positives = 57/150 (38%), Gaps = 13/150 (8%)
Query: 230 GPIDGPSKSGAEEQTSKDSPNKVVPEQPSRK----------DHSKPISNPSDNKELPKAD 279
G I GP + T K E P K + +K S+ +E A
Sbjct: 417 GSITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAI 476
Query: 280 TNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPP 339
T +LA K E EE + +EEV + + E ++++ EE
Sbjct: 477 TEELAVSMKEEKKEAAEEKEEEPEA---EEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQ 533
Query: 340 KEEKEKMSGSASSENREGTLSDSTGSEKDD 369
+EE+E+ G+ S + EG SEK++
Sbjct: 534 EEEEEEDEGAKSDQAEEGGSEKEGSSEKEE 563
Score = 32.0 bits (71), Expect = 1.1
Identities = 39/178 (21%), Positives = 69/178 (38%), Gaps = 24/178 (13%)
Query: 190 KDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSP 249
K+ ++ E + + + A K++P + EE+G + + G EE+ +D
Sbjct: 485 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEG--EKEEEEGQEEEEEEDEG 542
Query: 250 NKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQ 309
K +Q K S+ + E + +T A+ GEE + +
Sbjct: 543 AK--SDQAEEGGSEKEGSSEKEEGEQEEGETEAEAE-------------GEEAE----AK 583
Query: 310 EEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEK 367
EE K E +E+V KE D E+ P++ K + S E + + S EK
Sbjct: 584 EEKKVEEKSEEVATKEELVADAKVEK---PEKAKSPVPKSPVEEKGKSPVPKSPVEEK 638
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 81.6 bits (200), Expect = 1e-15
Identities = 87/340 (25%), Positives = 135/340 (39%), Gaps = 37/340 (10%)
Query: 55 KSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGS 114
+ PE + + + KS +A PE E + +K+ E + +G+ S
Sbjct: 120 EEEPEAEEEEVAAKKSPVKATAPEVK------EEEGEKEEEEGQEEEEEEDEGAKSDQAE 173
Query: 115 EAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQT 174
E + K+ +S E + + G++ AEA+ E AEAK +K KS A
Sbjct: 174 EGGSEKEGSS----EKEEGEQEEGETEAEAEGEE-------AEAKEEKKVEEKSEEVATK 222
Query: 175 TKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDG 234
+ V + + K KS E++ VP EK K KS EE+G
Sbjct: 223 EELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEK--GKSPVPKSPVEEKGKSPV 280
Query: 235 P------------SKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQ 282
P SKS EE+ P V E S+ + K + KE+ +A +
Sbjct: 281 PKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEE 340
Query: 283 LADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEE 342
+K + P + E+ SP +EE + T K + +T EEG P ++E
Sbjct: 341 KVEKKEEKP----KDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKET-KEEGKPLQQE 395
Query: 343 KEK-MSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAE 381
KEK +G EG+ + GS K+D+ NG G E
Sbjct: 396 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEE 435
Score = 51.6 bits (122), Expect = 1e-06
Identities = 80/345 (23%), Positives = 130/345 (37%), Gaps = 43/345 (12%)
Query: 24 ESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNK 83
E K ++A S S+ ++ G T++ E + + K E T +
Sbjct: 165 EGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEE 224
Query: 84 SGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAE 143
A+AK +K KS K + G P ++P + GKS
Sbjct: 225 LVADAKVEKPEKAKS----PVPKSPVEEKGKS------------PVPKSPVEEKGKSPVP 268
Query: 144 AQTPED---SPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAED 200
E+ SP + K SKS E + VP KS + K K ++
Sbjct: 269 KSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVP-KSPVEEAKSKAEVGKGEQKE 327
Query: 201 QTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRK 260
+ K+V K+ PK+ K +E+ P D P K AE +++ +VV S K
Sbjct: 328 EEEKEV-------KEAPKE--EKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVK 378
Query: 261 DHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTED 320
H + + KE K Q +K K E G + +E++ + +
Sbjct: 379 VHLE-----KETKEEGK-PLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVN---GE 429
Query: 321 VEPKEAEDDDTGPEEGSPPKEEKEKMSG----SASSENREGTLSD 361
VE KE + +T E+GS +EEK ++ S + E + G S+
Sbjct: 430 VEGKEEVEQET-KEKGSGREEEKGVVTNGLDLSPADEKKGGDKSE 473
Score = 35.4 bits (80), Expect = 0.10
Identities = 36/150 (24%), Positives = 57/150 (38%), Gaps = 13/150 (8%)
Query: 230 GPIDGPSKSGAEEQTSKDSPNKVVPEQPSRK----------DHSKPISNPSDNKELPKAD 279
G I GP + T K E P K + +K S+ +E A
Sbjct: 41 GSITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAI 100
Query: 280 TNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPP 339
T +LA K E EE + +EEV + + E ++++ EE
Sbjct: 101 TEELAVSMKEEKKEAAEEKEEEPEA---EEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQ 157
Query: 340 KEEKEKMSGSASSENREGTLSDSTGSEKDD 369
+EE+E+ G+ S + EG SEK++
Sbjct: 158 EEEEEEDEGAKSDQAEEGGSEKEGSSEKEE 187
Score = 32.0 bits (71), Expect = 1.1
Identities = 39/178 (21%), Positives = 69/178 (38%), Gaps = 24/178 (13%)
Query: 190 KDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSP 249
K+ ++ E + + + A K++P + EE+G + + G EE+ +D
Sbjct: 109 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEG--EKEEEEGQEEEEEEDEG 166
Query: 250 NKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQ 309
K +Q K S+ + E + +T A+ GEE + +
Sbjct: 167 AK--SDQAEEGGSEKEGSSEKEEGEQEEGETEAEAE-------------GEEAE----AK 207
Query: 310 EEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEK 367
EE K E +E+V KE D E+ P++ K + S E + + S EK
Sbjct: 208 EEKKVEEKSEEVATKEELVADAKVEK---PEKAKSPVPKSPVEEKGKSPVPKSPVEEK 262
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 75.5 bits (184), Expect = 9e-14
Identities = 85/383 (22%), Positives = 150/383 (39%), Gaps = 47/383 (12%)
Query: 28 QEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDS-PSKSSAEAQTPE--DTPNKS 84
+ E +P + +V T P ++ P+ K++ P S EA E D P
Sbjct: 1878 EAEGEAQPESEDVET-PEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESE 1936
Query: 85 GAEAKTQKDSSNKSGAEAKTQKGS----TSKSGSEAQTTKDSTSKSHPELQTPKDSTGKS 140
GAEA+ ++++ + AE +TQ S + ++ EAQ + E++T +++ G++
Sbjct: 1937 GAEAQEAEEAAQE--AEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVET-QEAEGEA 1993
Query: 141 GAEAQ---TPEDSPNRSGAEAKTQKDS------PSKSGSEAQTTKDVPNKSGADGQTPKD 191
E++ PE AE + Q +S P G EAQ + K+ D Q D
Sbjct: 1994 QPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESD 2053
Query: 192 GSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNK 251
G AE++ + AE + + + E +G P G E ++ K
Sbjct: 2054 GVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQ-PESEGVEAPEAEGEAQK 2112
Query: 252 VVP-EQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQE 310
E P + ++P S+ E P+A+ G+ P + E+ + P E
Sbjct: 2113 AEGIEAPETEGEAQP---ESEGIEAPEAE-------GEAQPESEGVEAQDAEGEAQPESE 2162
Query: 311 EVKSSEPTEDVEPK-----------EAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTL 359
+++ E E+ +P+ EA+ + G E E + ++ G + E E
Sbjct: 2163 GIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQ 2222
Query: 360 SDSTGSEKDDLYPNGSGNGSAES 382
+ G E P G ES
Sbjct: 2223 PEPEGVET----PEAEGEAQPES 2241
Score = 65.5 bits (158), Expect = 9e-11
Identities = 78/359 (21%), Positives = 142/359 (39%), Gaps = 28/359 (7%)
Query: 44 PSLSQRPG--------GSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSS 95
P LSQ PG GS + + + + PK ++ A AQ E + S A ++ +
Sbjct: 1732 PGLSQGPGVDEGEDGEGSQRLNRD-KDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEA 1790
Query: 96 NKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDS--PNR 153
+ G E +++G T GS + + + + Q P S G G EA E P
Sbjct: 1791 EQEG-EGISERGETGGQGSGHEDNLQGEAAAGGD-QDPGQSDGAEGIEAPEAEGEAQPES 1848
Query: 154 SGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDG----SSKSGAEDQTPKDVPNK 209
G EA + ++ EAQ + A+G+ + + ++ E Q +
Sbjct: 1849 EGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEA 1908
Query: 210 SGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNP 269
AEK+ + + E +G D P GAE Q ++++ + + + S+ I +
Sbjct: 1909 PEAEKEAQPETESVEALETEGE-DEPESEGAEAQEAEEAAQEA---EGQTQPESEVIESQ 1964
Query: 270 SDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPK----E 325
+E + A + ++ + E+ E++ + P+ E + E E+ +P+ E
Sbjct: 1965 EAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVE 2024
Query: 326 AEDDDTGPEEGSPPKEEKEKMSGSA--SSENREGTLSDSTGSEKDDLYPNGSGNGSAES 382
A+ G EE + E +K G A S+ E ++ E + G ES
Sbjct: 2025 AQPKSEG-EEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPES 2082
Score = 63.9 bits (154), Expect = 3e-10
Identities = 80/366 (21%), Positives = 142/366 (38%), Gaps = 38/366 (10%)
Query: 27 KQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGA 86
++ E +P + +V + ++ PE + + ++ + E P G
Sbjct: 1964 QEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGV 2023
Query: 87 EAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTS--KSHPELQTPKDSTGKSGAEA 144
EA+ + + G EA+ +G T K+ +AQ D ++ E Q + ++ EA
Sbjct: 2024 EAQPKSE-----GEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEA 2078
Query: 145 QTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPK 204
+ + AE + Q P G EA + K+ +G ++ +E
Sbjct: 2079 HPESEDVDAQEAEGEAQ---PESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEG---I 2132
Query: 205 DVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKD--SPNKVVPEQPSRKDH 262
+ P G E Q +G AE + P G E Q +++ P E P +
Sbjct: 2133 EAPEAEG-EAQPESEGVEAQDAEGEAQ---PESEGIEAQEAEEEAQPELEGVEAPEAEGE 2188
Query: 263 SKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVE 322
++P S+ E P+A+ G+ P E+ E + P E V++ E + +
Sbjct: 2189 AQP---ESEGIEAPEAE-------GEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQ 2238
Query: 323 PKEAEDDDTGPEEGSPP------KEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSG 376
P E+E + G ++GSP + E+ S S E+R T S G + P GS
Sbjct: 2239 P-ESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRP-TPPPSPGGDTPHQRP-GSQ 2295
Query: 377 NGSAES 382
G + S
Sbjct: 2296 TGPSSS 2301
Score = 48.5 bits (114), Expect = 1e-05
Identities = 82/342 (23%), Positives = 126/342 (36%), Gaps = 48/342 (14%)
Query: 9 LLNVAAAGAVPLLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPS 68
LL ++A P + ++ V PSAG S + P P P DS S
Sbjct: 732 LLGTSSATVTPAVHSDFVSGVSPHNAPSAGWAGDAGSRTCSPA------PIPPHTSDSCS 785
Query: 69 KSSAEAQTPE--DTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKS 126
KS A + E DTP S + + GA + S+ G+ Q +++
Sbjct: 786 KSGAASLGEEARDTPQPSSP--LVLQVGRPEQGAVGPHRSHCCSQPGT--QPAQEAQRGP 841
Query: 127 HPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADG 186
PE ++ G TP R + + S +GS Q+T P G
Sbjct: 842 SPE------ASWLCGRYCPTPP----RGRPCPQRRSSSCGSTGSSHQSTARGP------G 885
Query: 187 QTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSK 246
+P++G+ + G TP PN + + + G+ G E+ + +E+ S
Sbjct: 886 GSPQEGTRQPGP---TPSPGPNSGASRRSSASQGAGSRGLSEEKTLRSGGGPQGQEEASG 942
Query: 247 DSPNKVVPEQPSRKDHSKPISNPSDN-KELPKADTNQLADK-------GKLSPHAFKTES 298
SP+ + P + DN E P T +LAD+ G P +
Sbjct: 943 VSPSSLPRSSP-----EAVVREWLDNIPEEPILMTYELADETTGAAGGGLRGPEVDPGDD 997
Query: 299 GEETDLISPPQEEVKSSE--PTEDVEPKEA--EDDDTGPEEG 336
L P Q +S E P +D EP+ A DTGP+ G
Sbjct: 998 HSLEGLGEPAQAGQQSLEGDPGQDPEPEGALLGSSDTGPQSG 1039
Score = 44.3 bits (103), Expect = 2e-04
Identities = 41/191 (21%), Positives = 72/191 (37%), Gaps = 14/191 (7%)
Query: 41 STHPSLSQRPGGSTKSHPEPQTPKDSP---SKSSAEAQTPEDTPNKSGAEAKTQKDSSNK 97
S+H S ++ PGGS + P SP S +S + + ++ +E KT +
Sbjct: 875 SSHQSTARGPGGSPQEGTRQPGPTPSPGPNSGASRRSSASQGAGSRGLSEEKTLRSGGGP 934
Query: 98 SGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPE------LQTPKDSTGKSGAEAQTPE--- 148
G E + +S S + + PE + ++TG +G + PE
Sbjct: 935 QGQEEASGVSPSSLPRSSPEAVVREWLDNIPEEPILMTYELADETTGAAGGGLRGPEVDP 994
Query: 149 -DSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSS-KSGAEDQTPKDV 206
D + G Q S G Q + G+ P+ G GA + +
Sbjct: 995 GDDHSLEGLGEPAQAGQQSLEGDPGQDPEPEGALLGSSDTGPQSGEGVPQGAAPEGVSEA 1054
Query: 207 PNKSGAEKQTP 217
P ++GA+++ P
Sbjct: 1055 PAEAGADREAP 1065
Score = 34.7 bits (78), Expect = 0.18
Identities = 46/215 (21%), Positives = 74/215 (34%), Gaps = 16/215 (7%)
Query: 22 ATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTP 81
A E + E GV P + +P+ ++ EAQ +
Sbjct: 2169 AEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGV 2228
Query: 82 NKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKS--HPELQTPKDSTGK 139
AE + Q +S ++ E +KGS S + Q+ + S S S + TP S G
Sbjct: 2229 ETPEAEGEAQPESEGETQGE---KKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPG- 2284
Query: 140 SGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAE 199
TP P G++ S G+ Q + + G + AE
Sbjct: 2285 ----GDTPHQRP---GSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKSTGTPHAE 2337
Query: 200 DQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDG 234
+ + P S +E++ GS EQG +G
Sbjct: 2338 RKATRMYPESSTSEQEEAPLGSR---TPEQGASEG 2369
Score = 33.1 bits (74), Expect = 0.51
Identities = 65/335 (19%), Positives = 105/335 (31%), Gaps = 53/335 (15%)
Query: 23 TESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPN 82
T + EE S+ + +H S+ G P+ P K+ AE E +
Sbjct: 522 TPRARSEEGASSDSSASTGSHEGSSEWGG----------RPQGCPGKARAETSQQEASEG 571
Query: 83 KSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTK------DSTSKSHPELQTPKDS 136
A S +A+TQ T ++ A T + + S TP
Sbjct: 572 GDPASPALSLSSLRSDDLQAETQGQGTEQATGAAVTREPLVLGLSCSWDSEGASSTPSTC 631
Query: 137 TG--------KSGAEAQTPEDSPNRS-----GAEAKTQKDSPSKSGSEAQTTKDVP---- 179
T +S A A + SP G + + S ++ TK VP
Sbjct: 632 TSSQQGQRRHRSRASAMSSPSSPGLGRVAPRGHPRHSHYRKDTHSPLDSSVTKQVPRPPE 691
Query: 180 -NKSGADGQTPKDGSSKSGAEDQTPKDVPNKS----------GAEKQTPKDGSNKSGAEE 228
++ DG P+ S S Q ++ S G T +
Sbjct: 692 RRRACQDGSVPRYSGSSSSTRTQASGNLRPPSSGSLPSQDLLGTSSATVTPAVHSDFVSG 751
Query: 229 QGPIDGPSKSGAEEQTSKD-SPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQL---- 283
P + PS A + S+ SP + P S S + ++ P+ + +
Sbjct: 752 VSPHNAPSAGWAGDAGSRTCSPAPIPPHTSDSCSKSGAASLGEEARDTPQPSSPLVLQVG 811
Query: 284 -ADKGKLSPHAFKTESGEETDLISPPQEEVKSSEP 317
++G + PH S T P QE + P
Sbjct: 812 RPEQGAVGPHRSHCCSQPGT---QPAQEAQRGPSP 843
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 72.8 bits (177), Expect = 6e-13
Identities = 84/368 (22%), Positives = 138/368 (37%), Gaps = 50/368 (13%)
Query: 32 GVRPSAGNVSTHPSLSQRPG------------GSTKSHPEPQTPKDSPSKSSAEAQTPE- 78
G+R +G S H PG S PEP+ +P S +PE
Sbjct: 1446 GLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPEL 1505
Query: 79 DTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTG 138
+ + ++ +SS A+T G S+SGS + D + P+ ++ DS+
Sbjct: 1506 NNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQEL--DVKPSASPQERSESDSSP 1563
Query: 139 KSGAEAQTPEDSPNRSGAEAKTQKDS-----PSKSGSEAQTTKDVPNKSGADGQTPKDGS 193
S A+ +TP +RSG+ + S S+SGS + KD P ++ Q+ D S
Sbjct: 1564 DSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPE-VKDKP-RAAPRAQSGSDSS 1621
Query: 194 SKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVV 253
+ A P+ +P +S +SG+ +G P S + E + + P
Sbjct: 1622 PEPKA--PAPRALPRRS------------RSGSSSKGRGPSPEGSSSTESSPEHPPKSRT 1667
Query: 254 PEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQE--- 310
+ SR + + + + +L K +LS + S ET +PP+
Sbjct: 1668 ARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRS 1727
Query: 311 -EVKSSEPTEDVEPKEAEDDDTGP------EEGSPPKEEKEKMSGSASSENREGTLS--- 360
V S EP E + P G P + + S S RE T +
Sbjct: 1728 PSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRR 1787
Query: 361 -DSTGSEK 367
D +GS +
Sbjct: 1788 RDRSGSSQ 1795
Score = 59.3 bits (142), Expect = 7e-09
Identities = 68/309 (22%), Positives = 117/309 (37%), Gaps = 42/309 (13%)
Query: 62 TPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKD 121
TPK K + ++ + K+ K ++S +E+K +K + S+ ++
Sbjct: 184 TPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDK 243
Query: 122 STSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNK 181
+S PK A T DS A + S S+S S A T +
Sbjct: 244 KRKRSRSTTPAPKSRR----AHRSTSADS-------ASSSDTSRSRSRSAAAKT----HT 288
Query: 182 SGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAE 241
+ G++P S + G E P P + ++ + + + K + P + K E
Sbjct: 289 TALAGRSPSPASGRRG-EGDAPFSEPGTTSTQRPSSPETATK---QPSSPYEDKDKDKKE 344
Query: 242 EQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEE 301
+ ++ SP+ PE+ S + P P A T LA++ SP T
Sbjct: 345 KSATRPSPS---PERSS--------TGPE-----PPAPTPLLAERHGGSPQPLAT----- 383
Query: 302 TDLISPPQEEVKSSEPTEDVEPKEAED--DDTGPEEGSPPKEEKEKMSGSASSENREGTL 359
T L P + PT D P ++ + + E SPP + K+S ASS
Sbjct: 384 TPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKP 443
Query: 360 SDSTGSEKD 368
+ + GS ++
Sbjct: 444 APAPGSHRE 452
Score = 55.8 bits (133), Expect = 7e-08
Identities = 85/409 (20%), Positives = 154/409 (37%), Gaps = 83/409 (20%)
Query: 30 EAGVRPSAGNVST----HPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSG 85
++G P G++++ S++ + +S P+P+ +PS+ S +P + +
Sbjct: 845 KSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTP 904
Query: 86 AEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQ 145
+ SS + +A S SGS + + TS++ P +
Sbjct: 905 PRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLL 964
Query: 146 TPEDSPNRSGAEAKTQKDSP---SKSGS-------EAQTTKDVPNKSGADGQTPKDGSSK 195
S + K + ++P S SGS +AQT P+ SG+ P++ SK
Sbjct: 965 PRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPG-PSLSGSKSPCPQE-KSK 1022
Query: 196 SGAEDQTPKDVPNKSGAEKQTPK------------DGSNKSGAEEQGPIDGP------SK 237
P + +G + TP G +++ + + P S+
Sbjct: 1023 DSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSE 1082
Query: 238 SGAEEQTSKDSP-----------NKVVPEQPSRKDHSKPISNP--------------SDN 272
S + + S+ SP ++ P R+D + ++P SD+
Sbjct: 1083 SPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDS 1142
Query: 273 KELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEP--TEDVEPKEAEDDD 330
P D+N L + +L ES E+ L PPQE+ +S P + P +D
Sbjct: 1143 SSYPTVDSNSLLGQSRLE----TAESKEKMAL--PPQEDATASPPRQKDKFSPFPVQD-- 1194
Query: 331 TGPEEG--------SPPKEEKEKMSGSASS-ENREGTLSDSTGSEKDDL 370
PE +PP+E SG+ SS E +E + T S+ ++L
Sbjct: 1195 -RPESSLVFKDTLRTPPRER----SGAGSSPETKEQNSALPTSSQDEEL 1238
Score = 55.8 bits (133), Expect = 7e-08
Identities = 56/248 (22%), Positives = 99/248 (39%), Gaps = 24/248 (9%)
Query: 36 SAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSK--SSAEAQTPEDTPNKSGAEAKTQKD 93
S+G V+T S + G S P P P + +S AQ P A+ +
Sbjct: 2476 SSGAVATTTSSAGDHNGML-SVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSS 2534
Query: 94 SSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHP--------ELQTPKDSTGKSGAEAQ 145
SS+ S + + + S+S S S ++ DS S P + +P + ++ E +
Sbjct: 2535 SSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGR 2594
Query: 146 TPEDSP----NRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQ 201
PE +P RS + + + S S S S + ++ + S + + SS
Sbjct: 2595 PPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP 2654
Query: 202 TPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDG--PSKSGAEEQTSKDSPNKVVPEQPSR 259
P+ +P + +K P + ++S + PID S+S + + P+ QPS
Sbjct: 2655 GPQALPKPASPKKPPPGERRSRS---PRKPIDSLRDSRSLSYSPVERRRPS----PQPSP 2707
Query: 260 KDHSKPIS 267
+D S
Sbjct: 2708 RDQQSSSS 2715
Score = 55.1 bits (131), Expect = 1e-07
Identities = 51/229 (22%), Positives = 88/229 (38%), Gaps = 10/229 (4%)
Query: 6 ALVLLNVAAAGAVPLLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQ---- 61
AL L A ++ S + S+ + S+ S S G S PE
Sbjct: 2520 ALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRV 2579
Query: 62 -TPKDSPSKSSAEAQTPEDTP--NKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQT 118
+P +P ++ E + PE TP K + + + SS+ S + + + S+S S S + +
Sbjct: 2580 PSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2639
Query: 119 TKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAK---TQKDSPSKSGSEAQTT 175
+ S+S S P P A + P RS + K + +DS S S S +
Sbjct: 2640 SSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERR 2699
Query: 176 KDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKS 224
+ P S D Q+ + + +K E +P+ ++S
Sbjct: 2700 RPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRS 2748
Score = 53.9 bits (128), Expect = 3e-07
Identities = 59/271 (21%), Positives = 99/271 (36%), Gaps = 29/271 (10%)
Query: 34 RPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKD 93
R + H S S+ +S P P++ + S K +++ P A T D
Sbjct: 209 RKKSSKKKKHRSESESKKRKHRS-PTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSAD 267
Query: 94 SSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNR 153
S++ S TS+S S + K T+ ++P ++G+ G E P P
Sbjct: 268 SASSS---------DTSRSRSRSAAAKTHTTALAG--RSPSPASGRRG-EGDAPFSEPGT 315
Query: 154 SGAEAKTQKDSPSKSGSEAQTTKDVPNK-SGADGQTPKDGSSKSGAEDQTPKD-VPNKSG 211
+ + + ++ +K S KD K A +P S +G E P + + G
Sbjct: 316 TSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHG 375
Query: 212 AEKQ----TP------KDGSNKSGAEEQGPIDGPSK----SGAEEQTSKDSPNKVVPEQP 257
Q TP S S ++ P P K S +E P KV
Sbjct: 376 GSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHAS 435
Query: 258 SRKDHSKPISNPSDNKELPKADTNQLADKGK 288
S + KP P ++E+ + T++ G+
Sbjct: 436 SSPESPKPAPAPGSHREISSSPTSKNRSHGR 466
Score = 52.8 bits (125), Expect = 6e-07
Identities = 84/407 (20%), Positives = 147/407 (36%), Gaps = 48/407 (11%)
Query: 10 LNVAAAGAVPLLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSK 69
+N+A + A ++ V PSA N++ + P + +TP +
Sbjct: 2254 VNLADSRTPAAAAAMNLASPRTAVAPSAVNLAD----PRTPTAPAVNLAGARTPAALAAL 2309
Query: 70 SSAEAQTPEDTPNKSGAEAKTQKDSS-NKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHP 128
S + TP N + Q +S N G + + +GS + + + +
Sbjct: 2310 SLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGS-----RTAAALAPA 2364
Query: 129 ELQTPKDSTGKSGAEAQTPE-------------DSPNRSGAEAKTQKDSPSKSGSEAQTT 175
L + + + SGA +P P A ++T +PS+S T+
Sbjct: 2365 SLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQS---RMTS 2421
Query: 176 KDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQ------TPKDGSNK------ 223
+ P+ S GQ P S A+DQ VP+ + + TP GS
Sbjct: 2422 ERAPSPSSRMGQAPSQ-SLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAV 2480
Query: 224 -----SGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKA 278
S + G + P+ G + P +QPS +P + +
Sbjct: 2481 ATTTSSAGDHNGMLSVPAP-GVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSS 2539
Query: 279 DTNQLADKGKLSPHAFKTESGEETDLIS-PPQEEVKSSE-PTEDVEPKEAEDDDTGPEEG 336
++ + S + S +++ S P Q EV P+ PKEA + P E
Sbjct: 2540 SSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGR-PPEP 2598
Query: 337 SPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAESS 383
+P K ++ S S+SS + + S S+ S + S + S+ SS
Sbjct: 2599 TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645
Score = 43.1 bits (100), Expect = 5e-04
Identities = 53/261 (20%), Positives = 98/261 (37%), Gaps = 41/261 (15%)
Query: 13 AAAGAVPLLATESVKQEEAGVRPSAGNVSTHPSLSQRP------GGSTKSHPEPQTPKDS 66
++ G P T + + G S ++T P LSQ P T+ P++P+
Sbjct: 357 SSTGPEPPAPTPLLAERHGG---SPQPLATTP-LSQEPVNPPSEASPTRDRSPPKSPEKL 412
Query: 67 PSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKS---GAEAKTQKGSTSKSGSEAQTTKDST 123
P SS+E+ P P K A + +S + G+ + TSK+ S + +D
Sbjct: 413 PQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRD-- 470
Query: 124 SKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSG 183
KSH TP G+S + A + +++ +P+K G +
Sbjct: 471 -KSHS--HTPSRRMGRSRSPA---------TAKRGRSRSRTPTKRGHSRSRSPQWRRSRS 518
Query: 184 ADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQ 243
A + G S+S P + G + + G ++S ++ ++ G
Sbjct: 519 AQ----RWGRSRS----------PQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHS 564
Query: 244 TSKDSPNKVVPEQPSRKDHSK 264
S + + P+R+ S+
Sbjct: 565 RSPATRGRSRSRTPARRGRSR 585
Score = 43.1 bits (100), Expect = 5e-04
Identities = 53/235 (22%), Positives = 94/235 (40%), Gaps = 20/235 (8%)
Query: 40 VSTHPSLS-QRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKS 98
+S SLS P KS P+ + S+ A+++TP S + QK +
Sbjct: 773 LSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSR 832
Query: 99 GAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTP-KDSTGKSGAEAQTPEDSPNR---S 154
+ + + KSG+ + ++ +++ + TP + S +S + + +P+R S
Sbjct: 833 QSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCS 892
Query: 155 GAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEK 214
G+ K S S ++++ P + S SG+ +P V +++
Sbjct: 893 GSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQR---SHSGSSSPSPSRVTSRT---- 945
Query: 215 QTPKDGSNKSGAE--EQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPIS 267
TP+ + S E + S SG S KV PE P R+ HS IS
Sbjct: 946 -TPRRSRSVSPCSNVESRLLPRYSHSG-----SSSPDTKVKPETPPRQSHSGSIS 994
Score = 42.0 bits (97), Expect = 0.001
Identities = 52/273 (19%), Positives = 100/273 (36%), Gaps = 50/273 (18%)
Query: 15 AGAVPLLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKD--------- 65
+G+ P + ++S S+ V P + R + S PEP+ P
Sbjct: 1579 SGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRS 1638
Query: 66 ---------SPSKSSAEAQTPEDTP--------NKSGAEAKTQKDS-----SNKSGAEA- 102
SP SS+ +PE P ++S E KT+ + S++S E
Sbjct: 1639 GSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELT 1698
Query: 103 -KTQKGSTSKSGSEAQTTKDSTSKSH---PELQTPKDSTGKSGAEAQTPEDSPNRSGAEA 158
K + S+S S + T+ T H P + +P+ + + + SP
Sbjct: 1699 RKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSR 1758
Query: 159 KTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPK 218
+ + SP G + ++ K+ + + GSS+S + + +S + + +
Sbjct: 1759 RGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRR------QRSRSRSRVTR 1812
Query: 219 DGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNK 251
SG + P A +++S+ S +
Sbjct: 1813 RRRGGSGYHSRSP--------ARQESSRTSSRR 1837
Score = 40.8 bits (94), Expect = 0.002
Identities = 50/282 (17%), Positives = 97/282 (34%), Gaps = 27/282 (9%)
Query: 34 RPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKD 93
R +A T + P ++ E P P +S + + +T K + KD
Sbjct: 280 RSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKD 339
Query: 94 SSNKS-GAEAKTQKGSTSKSGSEAQTTKDSTSKSH-----PELQTP----------KDST 137
K A + S +G E ++ H P TP + S
Sbjct: 340 KDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASP 399
Query: 138 GKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQ--------TP 189
+ + ++PE P S +E+ P+K A ++ + P + A G T
Sbjct: 400 TRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTS 459
Query: 190 KDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEE-QTSKDS 248
K+ S D++ P++ ++P G S+S + + + S+ +
Sbjct: 460 KNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSA 519
Query: 249 PNKVVPEQPSRKDHSKPISNP--SDNKELPKADTNQLADKGK 288
P R+ S+ P S ++ + ++ A +G+
Sbjct: 520 QRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGR 561
Score = 40.0 bits (92), Expect = 0.004
Identities = 53/317 (16%), Positives = 114/317 (35%), Gaps = 14/317 (4%)
Query: 54 TKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSG 113
T+S ++ SP++ S +++ TP + G +S + ++ S+S
Sbjct: 627 TRSPVRRRSRSRSPARRSGRSRSR--TPARRGRSRSRTPARRGRSRSRTPARRSGRSRSR 684
Query: 114 SEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQ 173
+ A+ + + + + + ++TP+ + + K S+ S +
Sbjct: 685 TPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSN 744
Query: 174 TTKDVPNKSGADGQTPKDGSSKSGAEDQTP--KDVPNKSGAEKQTPKDGSNKSGAEEQGP 231
++ ++ + ++ S +S A+ + + + S KQ + +S + P
Sbjct: 745 SSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQP 804
Query: 232 IDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKAD---TNQLADKGK 288
++S P K + PSR+ HS +P P T+ A++
Sbjct: 805 KAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQS 864
Query: 289 LSPH---AFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEK 345
++P F++ E +P + S P K + P S P + K K
Sbjct: 865 VTPQRRSCFESSPDPELKSRTPSRHSCSGSSPP---RVKSSTPPRQSPSRSSSP-QPKVK 920
Query: 346 MSGSASSENREGTLSDS 362
S + G+ S S
Sbjct: 921 AIISPRQRSHSGSSSPS 937
Score = 35.0 bits (79), Expect = 0.13
Identities = 71/388 (18%), Positives = 123/388 (31%), Gaps = 69/388 (17%)
Query: 2 RFVVALVLLNVAAAGAVPLLATESVKQEEAGVRPSAGNVSTHPSLSQRP----GGSTKSH 57
R AL L++ +G P A SA V + + P G T +
Sbjct: 2301 RTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAA 2360
Query: 58 PEPQT---PKDSPSKSSAEAQTPE-------------DTPNKSGAEAKTQKDSSNKSGAE 101
P + + +P+ S A +P P A ++T + ++S
Sbjct: 2361 LAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMT 2420
Query: 102 AKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAE-AQTPEDSPNRS---GAE 157
++ +S+ G + ++ P P + +S AQT + ++S GA
Sbjct: 2421 SERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAV 2480
Query: 158 AKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTP 217
A T + +G + VP+ G+ P + +GA Q P + A+++
Sbjct: 2481 ATTTSSAGDHNGMLSVPAPGVPHSD--VGEPP----ASTGA--QQPSALAALQPAKERRS 2532
Query: 218 KDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPK 277
S+ S + S S + +S DS +P QP P P+
Sbjct: 2533 SSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA------- 2585
Query: 278 ADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGS 337
P+E V+ P E K + S
Sbjct: 2586 ------------------------------PKEAVREGRPPEPTPAKRKRRSSSSSSSSS 2615
Query: 338 PPKEEKEKMSGSASSENREGTLSDSTGS 365
S S+SS + + S S+ S
Sbjct: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
Score = 33.1 bits (74), Expect = 0.51
Identities = 52/238 (21%), Positives = 73/238 (30%), Gaps = 52/238 (21%)
Query: 151 PNRSGAEAKTQKDSPSK--------SGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQT 202
P R EAK P K S S + T K K D + SS ++
Sbjct: 153 PQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKS 212
Query: 203 PKDVPNKSGAEKQ-------TPKD---GSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKV 252
K ++S +E + TPK +K + P A TS DS +
Sbjct: 213 SKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSAS-- 270
Query: 253 VPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGE-------ETDLI 305
S S K T LA + SP + + G+ T
Sbjct: 271 ----------SSDTSRSRSRSAAAKTHTTALAGRSP-SPASGRRGEGDAPFSEPGTTSTQ 319
Query: 306 SPPQEEVKSSEPTEDVEPKE--------------AEDDDTGPEEGSPPKEEKEKMSGS 349
P E + +P+ E K+ E TGPE +P E+ GS
Sbjct: 320 RPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGS 377
Score = 32.7 bits (73), Expect = 0.67
Identities = 60/333 (18%), Positives = 120/333 (36%), Gaps = 37/333 (11%)
Query: 58 PEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQK-----GSTSKS 112
P+P+ + S S+S E ++SG+ T + T++ G S+S
Sbjct: 1765 PKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRS 1824
Query: 113 GSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSG--- 169
+ ++++ S+ + +TP S +S + +RS A T + S S++
Sbjct: 1825 PARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLIS 1884
Query: 170 ---SEAQTTKDVPNKSGADGQTPKDGS-------SKSGAEDQTPKDVPNKSGAE------ 213
S ++T+ +S + + S S+ + +TP +S +
Sbjct: 1885 RRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRR 1944
Query: 214 ---KQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSR-KDHSKPISNP 269
+TP +S + S+S T + S ++ P R + + P++
Sbjct: 1945 RSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRR 2004
Query: 270 SDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDD 329
+ + +P A + S T L+ P++ +S P +
Sbjct: 2005 RSRSRTSPVTRRRSRSR---TPPAIRRRSRSRTPLL--PRKRSRSRSPLAIRRRSRSRTP 2059
Query: 330 DTGPEEGS----PPKEEKEKMSGSASSENREGT 358
T + S PP + SGS+S +R T
Sbjct: 2060 RTARGKRSLTRSPPAIRRRSASGSSSDRSRSAT 2092
Score = 31.6 bits (70), Expect = 1.5
Identities = 89/438 (20%), Positives = 148/438 (33%), Gaps = 95/438 (21%)
Query: 32 GVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTP---------------------------- 63
G+ G+ T S+ Q+ GGS P P+ P
Sbjct: 2134 GMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTA 2193
Query: 64 KDSPSKSSA-----EAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGS---- 114
+ PS S+A +Q P P S A +S A A +++++ +
Sbjct: 2194 RPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTA 2253
Query: 115 -EAQTTKDSTSKSHPELQTPKDSTGKSG---AEAQTP-EDSPNRSGAEAKTQKDSPSKSG 169
++ + + L +P+ + S A+ +TP + N +GA + S +G
Sbjct: 2254 VNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTG 2313
Query: 170 SEAQTTKDVPNKSGADGQTP----------------------KDGSSKSGAEDQTPKDVP 207
S T S Q P + ++ + A + + P
Sbjct: 2314 SGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAP 2373
Query: 208 NKSGAEKQTPK---------DGSNK----SGAEEQGPIDGPSKS--GAEEQTSKDSPNKV 252
SGA +P+ G A + P PS+S +E S S
Sbjct: 2374 ALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQ 2433
Query: 253 VPEQ----PSRKDHSKPISNP-SDNKELPKADTNQLADKGKLSPHAFKT---ESGEETDL 304
P Q P++ P+ + SD A T +A LS A T +G+ +
Sbjct: 2434 APSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGM 2493
Query: 305 ISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTG 364
+S P V P DV A P + + KE+ S S+SS + + S S+
Sbjct: 2494 LSVPAPGV----PHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSS 2549
Query: 365 SEKDDLYPNGSGNGSAES 382
S + SG+ S++S
Sbjct: 2550 SSSS----SSSGSSSSDS 2563
Score = 31.2 bits (69), Expect = 1.9
Identities = 41/191 (21%), Positives = 77/191 (40%), Gaps = 14/191 (7%)
Query: 40 VSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSG 99
V+ S S+ P +T+ +TP + +S ++TP T +S ++T + +S
Sbjct: 1930 VTRRRSRSRTP--TTRRRSRSRTPPVTRRRS--RSRTPPVTRRRS--RSRTSPITRRRSR 1983
Query: 100 AEAKTQKGSTSKSGSEAQTTKDSTSKSHP------ELQTPKDSTGKSGAEAQTPEDSPNR 153
+ S+S + T + S S++ P +TP +S + +R
Sbjct: 1984 SRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSR 2043
Query: 154 SGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAE 213
S + ++ S S++ A+ + + A + GSS + TP N SG+
Sbjct: 2044 SRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGS- 2102
Query: 214 KQTPKDGSNKS 224
+TP N S
Sbjct: 2103 -RTPPVALNSS 2112
Score = 29.6 bits (65), Expect = 5.6
Identities = 34/181 (18%), Positives = 70/181 (38%), Gaps = 13/181 (7%)
Query: 42 THPSLSQRPGGSTKSHPE-----PQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSN 96
T + R S S PE P + SPS SS E + + + + + +++
Sbjct: 1698 TRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTS 1757
Query: 97 KSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGA 156
+ G + +S S ++ K T++ +D +G S + ++ + S +RS
Sbjct: 1758 RRGRSPSPKPRGLQRSRSRSRREKTRTTRR-------RDRSGSSQSTSRRRQRSRSRSRV 1810
Query: 157 EAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQT 216
+ + S S S A+ + G++ +S+ + +T P K + +
Sbjct: 1811 TRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRT-SPAPWKRSRSRAS 1869
Query: 217 P 217
P
Sbjct: 1870 P 1870
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 71.2 bits (173), Expect = 2e-12
Identities = 90/383 (23%), Positives = 154/383 (40%), Gaps = 59/383 (15%)
Query: 20 LLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPS----------- 68
L ++SV E A + S HPS S+ T + + P D
Sbjct: 382 LRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFE 441
Query: 69 KSSAEAQTPEDTPNKSGAEAKTQKDSSN---KSGAEAKTQKGSTSKSGSEAQTTKDSTSK 125
+ ++E E +P K E +K+S K G E + S+ G+ + +++ + K
Sbjct: 442 EGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQ-KESEEGNPVRGSEEDSPK 500
Query: 126 SHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGAD 185
+ +T K+ ++G ++ +D S E K+S + SE ++ +D K
Sbjct: 501 KESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKES-EEDDSEKESDEDCSEKQS-- 557
Query: 186 GQTPKDGSSKSGAEDQTPKDVPNKSGAE---------KQTPKDGSNKSGAEEQGPIDGPS 236
+DGS + E+ KD+ ++ G+E K+ ++ S S E+ G
Sbjct: 558 ----EDGSEREFEENGLEKDL-DEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLD 612
Query: 237 KSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKT 296
+ G+E + +DS K + + K + SD KE + AD+ L K
Sbjct: 613 EEGSEREFDEDSDEK----EEEEDTYEKVFDDESDEKE-----DEEYADEKGLEAADKKA 663
Query: 297 ESGEETDLI----SPPQEEVKSSEPTEDVEPKEAEDDDTG-----PEEGSPPK-----EE 342
E G+ + + ++E + ED + K EDDD+ EE S K +E
Sbjct: 664 EEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDE 723
Query: 343 KEKMSGSASSENREGTLSDSTGS 365
+ + G S E EG L STGS
Sbjct: 724 RGTLGGFGSVE--EGPL--STGS 742
Score = 56.2 bits (134), Expect = 6e-08
Identities = 68/309 (22%), Positives = 128/309 (41%), Gaps = 28/309 (9%)
Query: 77 PEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDS 136
PE +++ + + + S A ++ STSK ++ T + + E + K
Sbjct: 376 PEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTE 435
Query: 137 TGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKS 196
G E +E ++ SP K E P K +G PK G S
Sbjct: 436 DGGEFEEG----------ASENNAKESSPEKEAEEG-----CPEKESEEG-CPKRGFEGS 479
Query: 197 GAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQ 256
++ ++ + P + G+E+ +PK S K + +G +K +E+ +K+S +V P +
Sbjct: 480 CSQKESEEGNPVR-GSEEDSPKKESKKKTLKNDCEENGLAKE-SEDDLNKESEEEVGPTK 537
Query: 257 PSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSE 316
S +D S+ S+ +++ + + + ++ L E G E +L E V E
Sbjct: 538 ESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDL--DEEGSEKEL----HENVLDKE 591
Query: 317 PTE-DVEPKEAEDDDTGP---EEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYP 372
E D E E EDD + EEGS + +++ + E D + ++D+ Y
Sbjct: 592 LEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYA 651
Query: 373 NGSGNGSAE 381
+ G +A+
Sbjct: 652 DEKGLEAAD 660
Score = 44.7 bits (104), Expect = 2e-04
Identities = 53/253 (20%), Positives = 97/253 (38%), Gaps = 31/253 (12%)
Query: 130 LQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTK---DVPNKSGADG 186
L P+ + G +++ + + S A ++ S SK ++ T + P
Sbjct: 373 LNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFE 432
Query: 187 QTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSK 246
+T G + GA + K+ + AE+ P+ S EE P G S +++++ +
Sbjct: 433 KTEDGGEFEEGASENNAKESSPEKEAEEGCPEKES-----EEGCPKRGFEGSCSQKESEE 487
Query: 247 DSPNKVVPEQ-PSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLI 305
+P + E P ++ K + N + L K + L ES EE
Sbjct: 488 GNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDL-----------NKESEEEVGPT 536
Query: 306 SPPQEEVKSSEPTEDVEPKEAED------DDTG-----PEEGSPPKEEKEKMSGSASSEN 354
+E+ E ED K++ED ++ G EEGS + + + +
Sbjct: 537 KESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEEND 596
Query: 355 REGTLSDSTGSEK 367
E + + GSEK
Sbjct: 597 SENSEFEDDGSEK 609
Score = 41.6 bits (96), Expect = 0.001
Identities = 45/228 (19%), Positives = 92/228 (40%), Gaps = 13/228 (5%)
Query: 141 GAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAED 200
G EA NR + + S S A+ + P+ S + Q G + D
Sbjct: 368 GWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPID 427
Query: 201 QTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRK 260
+ K + G E + +G++++ A+E P + E+++ + P + S+K
Sbjct: 428 EK-KFEKTEDGGEFE---EGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQK 483
Query: 261 DHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTED 320
+ + ++ PK ++ + K + ES E DL +EEV ++ +E+
Sbjct: 484 ESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKES--EDDLNKESEEEVGPTKESEE 541
Query: 321 VEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKD 368
+ ++ D+D ++ E + + +G + E GSEK+
Sbjct: 542 DDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEE-------GSEKE 582
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 71.2 bits (173), Expect = 2e-12
Identities = 90/383 (23%), Positives = 154/383 (40%), Gaps = 59/383 (15%)
Query: 20 LLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPS----------- 68
L ++SV E A + S HPS S+ T + + P D
Sbjct: 382 LRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFE 441
Query: 69 KSSAEAQTPEDTPNKSGAEAKTQKDSSN---KSGAEAKTQKGSTSKSGSEAQTTKDSTSK 125
+ ++E E +P K E +K+S K G E + S+ G+ + +++ + K
Sbjct: 442 EGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQ-KESEEGNPVRGSEEDSPK 500
Query: 126 SHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGAD 185
+ +T K+ ++G ++ +D S E K+S + SE ++ +D K
Sbjct: 501 KESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKES-EEDDSEKESDEDCSEKQS-- 557
Query: 186 GQTPKDGSSKSGAEDQTPKDVPNKSGAE---------KQTPKDGSNKSGAEEQGPIDGPS 236
+DGS + E+ KD+ ++ G+E K+ ++ S S E+ G
Sbjct: 558 ----EDGSEREFEENGLEKDL-DEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLD 612
Query: 237 KSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKT 296
+ G+E + +DS K + + K + SD KE + AD+ L K
Sbjct: 613 EEGSEREFDEDSDEK----EEEEDTYEKVFDDESDEKE-----DEEYADEKGLEAADKKA 663
Query: 297 ESGEETDLI----SPPQEEVKSSEPTEDVEPKEAEDDDTG-----PEEGSPPK-----EE 342
E G+ + + ++E + ED + K EDDD+ EE S K +E
Sbjct: 664 EEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDE 723
Query: 343 KEKMSGSASSENREGTLSDSTGS 365
+ + G S E EG L STGS
Sbjct: 724 RGTLGGFGSVE--EGPL--STGS 742
Score = 56.2 bits (134), Expect = 6e-08
Identities = 68/309 (22%), Positives = 128/309 (41%), Gaps = 28/309 (9%)
Query: 77 PEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDS 136
PE +++ + + + S A ++ STSK ++ T + + E + K
Sbjct: 376 PEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTE 435
Query: 137 TGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKS 196
G E +E ++ SP K E P K +G PK G S
Sbjct: 436 DGGEFEEG----------ASENNAKESSPEKEAEEG-----CPEKESEEG-CPKRGFEGS 479
Query: 197 GAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQ 256
++ ++ + P + G+E+ +PK S K + +G +K +E+ +K+S +V P +
Sbjct: 480 CSQKESEEGNPVR-GSEEDSPKKESKKKTLKNDCEENGLAKE-SEDDLNKESEEEVGPTK 537
Query: 257 PSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSE 316
S +D S+ S+ +++ + + + ++ L E G E +L E V E
Sbjct: 538 ESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDL--DEEGSEKEL----HENVLDKE 591
Query: 317 PTE-DVEPKEAEDDDTGP---EEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYP 372
E D E E EDD + EEGS + +++ + E D + ++D+ Y
Sbjct: 592 LEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYA 651
Query: 373 NGSGNGSAE 381
+ G +A+
Sbjct: 652 DEKGLEAAD 660
Score = 44.7 bits (104), Expect = 2e-04
Identities = 53/253 (20%), Positives = 97/253 (38%), Gaps = 31/253 (12%)
Query: 130 LQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTK---DVPNKSGADG 186
L P+ + G +++ + + S A ++ S SK ++ T + P
Sbjct: 373 LNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFE 432
Query: 187 QTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSK 246
+T G + GA + K+ + AE+ P+ S EE P G S +++++ +
Sbjct: 433 KTEDGGEFEEGASENNAKESSPEKEAEEGCPEKES-----EEGCPKRGFEGSCSQKESEE 487
Query: 247 DSPNKVVPEQ-PSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLI 305
+P + E P ++ K + N + L K + L ES EE
Sbjct: 488 GNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDL-----------NKESEEEVGPT 536
Query: 306 SPPQEEVKSSEPTEDVEPKEAED------DDTG-----PEEGSPPKEEKEKMSGSASSEN 354
+E+ E ED K++ED ++ G EEGS + + + +
Sbjct: 537 KESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEEND 596
Query: 355 REGTLSDSTGSEK 367
E + + GSEK
Sbjct: 597 SENSEFEDDGSEK 609
Score = 41.6 bits (96), Expect = 0.001
Identities = 45/228 (19%), Positives = 92/228 (40%), Gaps = 13/228 (5%)
Query: 141 GAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAED 200
G EA NR + + S S A+ + P+ S + Q G + D
Sbjct: 368 GWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPID 427
Query: 201 QTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRK 260
+ K + G E + +G++++ A+E P + E+++ + P + S+K
Sbjct: 428 EK-KFEKTEDGGEFE---EGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQK 483
Query: 261 DHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTED 320
+ + ++ PK ++ + K + ES E DL +EEV ++ +E+
Sbjct: 484 ESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKES--EDDLNKESEEEVGPTKESEE 541
Query: 321 VEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKD 368
+ ++ D+D ++ E + + +G + E GSEK+
Sbjct: 542 DDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEE-------GSEKE 582
>gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 70.5 bits (171), Expect = 3e-12
Identities = 93/363 (25%), Positives = 149/363 (41%), Gaps = 34/363 (9%)
Query: 24 ESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEA---QTPEDT 80
ES +E P + ++HP P KS E PK+ + E ED
Sbjct: 12 ESDASQEGDDLPKSSANTSHPKQDDSP----KSSEETIQPKEGDIPKAPEETIQSKKEDL 67
Query: 81 PNKSGAEAKTQKDSSNKSGAEAKTQK-GSTSKSGSEAQTTKDSTSKSHPE--LQTPKDST 137
P S + ++ + KS A+ K G+ K+ + K+ PE +Q+ K+
Sbjct: 68 PKSSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDL 127
Query: 138 GKSGAEAQTPE--DSPNRSGAEAKTQKDSPSKSGSEAQTTK--DVPNKSGADGQTPKDGS 193
KS EA P+ D P S + + + +K+ + K D+P KS + PK+G
Sbjct: 128 PKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIP-KSPEETIQPKEGD 186
Query: 194 -SKSGAEDQTPK--DVPNKSGAEKQTPKDGS-NKSGAEEQGPIDGPSKSGAEEQTS-KDS 248
KS A+ PK ++P K+ + PK+G +KS E P +G EE K+
Sbjct: 187 IPKSSAKPIQPKLGNIP-KASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEG 245
Query: 249 PNKVVPE---QPSRKDHSKPISNPSDNKE--LPKADTNQLADK-GKLSPHAFKTESGEET 302
PE QP D K + KE +PK+ + K G + + +E
Sbjct: 246 DIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEG 305
Query: 303 DLISPPQEEVKSSEPT------EDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENRE 356
D+ P++ ++ E E + PKE D PEE PKE+ S ++ ++E
Sbjct: 306 DIPKSPKQAIQPKEGDIPKSLEEAIPPKEI-DIPKSPEETIQPKEDDSPKSLEEATPSKE 364
Query: 357 GTL 359
G +
Sbjct: 365 GDI 367
Score = 45.8 bits (107), Expect = 8e-05
Identities = 52/241 (21%), Positives = 88/241 (36%), Gaps = 44/241 (18%)
Query: 166 SKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPK--DVPNKSGAEKQTPKDGSNK 223
++ +Q D+P S +D S KS E PK D+P Q+ K+ K
Sbjct: 10 TEESDASQEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPK 69
Query: 224 SGAEEQGPIDG-----------PSKSGAEEQTSKDSPNKV--VPEQPSRKDHSKPISNPS 270
S + P + P + + K S K +P+ P SK P
Sbjct: 70 SSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPK 129
Query: 271 DNKE--------LPKADTNQLADK-GKLSPHAFKTESGEETDLISPPQEEVKSSE----- 316
++E +PK+ + K G ++ + K +E+D+ P+E ++ E
Sbjct: 130 SSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPK 189
Query: 317 -------------PTEDVEPKEAEDDD--TGPEEGSPPKEEKEKMSGSASSENREGTLSD 361
P V+P + ++ D PEE PKE S + + +EG +
Sbjct: 190 SSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPK 249
Query: 362 S 362
S
Sbjct: 250 S 250
Score = 32.7 bits (73), Expect = 0.67
Identities = 38/163 (23%), Positives = 59/163 (36%), Gaps = 33/163 (20%)
Query: 201 QTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRK 260
Q D+P S +D S KS E P +G +P+ P
Sbjct: 17 QEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGD-----------------IPKAPEET 59
Query: 261 DHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTED 320
SK ++LPK+ + K P + + + L + P+ VK S+P E
Sbjct: 60 IQSK-------KEDLPKSSEKAIQPKESNIPKS--SAKPIQPKLGNIPKASVKPSQPKEG 110
Query: 321 VEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDST 363
PK PEE K+E S + + +EG + S+
Sbjct: 111 DIPK-------APEETIQSKKEDLPKSSEEAIQPKEGDIPKSS 146
>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo
sapiens]
Length = 553
Score = 70.5 bits (171), Expect = 3e-12
Identities = 93/363 (25%), Positives = 149/363 (41%), Gaps = 34/363 (9%)
Query: 24 ESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEA---QTPEDT 80
ES +E P + ++HP P KS E PK+ + E ED
Sbjct: 79 ESDASQEGDDLPKSSANTSHPKQDDSP----KSSEETIQPKEGDIPKAPEETIQSKKEDL 134
Query: 81 PNKSGAEAKTQKDSSNKSGAEAKTQK-GSTSKSGSEAQTTKDSTSKSHPE--LQTPKDST 137
P S + ++ + KS A+ K G+ K+ + K+ PE +Q+ K+
Sbjct: 135 PKSSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDL 194
Query: 138 GKSGAEAQTPE--DSPNRSGAEAKTQKDSPSKSGSEAQTTK--DVPNKSGADGQTPKDGS 193
KS EA P+ D P S + + + +K+ + K D+P KS + PK+G
Sbjct: 195 PKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIP-KSPEETIQPKEGD 253
Query: 194 -SKSGAEDQTPK--DVPNKSGAEKQTPKDGS-NKSGAEEQGPIDGPSKSGAEEQTS-KDS 248
KS A+ PK ++P K+ + PK+G +KS E P +G EE K+
Sbjct: 254 IPKSSAKPIQPKLGNIP-KASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEG 312
Query: 249 PNKVVPE---QPSRKDHSKPISNPSDNKE--LPKADTNQLADK-GKLSPHAFKTESGEET 302
PE QP D K + KE +PK+ + K G + + +E
Sbjct: 313 DIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEG 372
Query: 303 DLISPPQEEVKSSEPT------EDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENRE 356
D+ P++ ++ E E + PKE D PEE PKE+ S ++ ++E
Sbjct: 373 DIPKSPKQAIQPKEGDIPKSLEEAIPPKEI-DIPKSPEETIQPKEDDSPKSLEEATPSKE 431
Query: 357 GTL 359
G +
Sbjct: 432 GDI 434
Score = 45.8 bits (107), Expect = 8e-05
Identities = 52/241 (21%), Positives = 88/241 (36%), Gaps = 44/241 (18%)
Query: 166 SKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPK--DVPNKSGAEKQTPKDGSNK 223
++ +Q D+P S +D S KS E PK D+P Q+ K+ K
Sbjct: 77 TEESDASQEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPK 136
Query: 224 SGAEEQGPIDG-----------PSKSGAEEQTSKDSPNKV--VPEQPSRKDHSKPISNPS 270
S + P + P + + K S K +P+ P SK P
Sbjct: 137 SSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPK 196
Query: 271 DNKE--------LPKADTNQLADK-GKLSPHAFKTESGEETDLISPPQEEVKSSE----- 316
++E +PK+ + K G ++ + K +E+D+ P+E ++ E
Sbjct: 197 SSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPK 256
Query: 317 -------------PTEDVEPKEAEDDD--TGPEEGSPPKEEKEKMSGSASSENREGTLSD 361
P V+P + ++ D PEE PKE S + + +EG +
Sbjct: 257 SSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPK 316
Query: 362 S 362
S
Sbjct: 317 S 317
Score = 32.7 bits (73), Expect = 0.67
Identities = 38/163 (23%), Positives = 59/163 (36%), Gaps = 33/163 (20%)
Query: 201 QTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRK 260
Q D+P S +D S KS E P +G +P+ P
Sbjct: 84 QEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGD-----------------IPKAPEET 126
Query: 261 DHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTED 320
SK ++LPK+ + K P + + + L + P+ VK S+P E
Sbjct: 127 IQSK-------KEDLPKSSEKAIQPKESNIPKS--SAKPIQPKLGNIPKASVKPSQPKEG 177
Query: 321 VEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDST 363
PK PEE K+E S + + +EG + S+
Sbjct: 178 DIPK-------APEETIQSKKEDLPKSSEEAIQPKEGDIPKSS 213
>gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 70.5 bits (171), Expect = 3e-12
Identities = 93/363 (25%), Positives = 149/363 (41%), Gaps = 34/363 (9%)
Query: 24 ESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEA---QTPEDT 80
ES +E P + ++HP P KS E PK+ + E ED
Sbjct: 12 ESDASQEGDDLPKSSANTSHPKQDDSP----KSSEETIQPKEGDIPKAPEETIQSKKEDL 67
Query: 81 PNKSGAEAKTQKDSSNKSGAEAKTQK-GSTSKSGSEAQTTKDSTSKSHPE--LQTPKDST 137
P S + ++ + KS A+ K G+ K+ + K+ PE +Q+ K+
Sbjct: 68 PKSSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDL 127
Query: 138 GKSGAEAQTPE--DSPNRSGAEAKTQKDSPSKSGSEAQTTK--DVPNKSGADGQTPKDGS 193
KS EA P+ D P S + + + +K+ + K D+P KS + PK+G
Sbjct: 128 PKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIP-KSPEETIQPKEGD 186
Query: 194 -SKSGAEDQTPK--DVPNKSGAEKQTPKDGS-NKSGAEEQGPIDGPSKSGAEEQTS-KDS 248
KS A+ PK ++P K+ + PK+G +KS E P +G EE K+
Sbjct: 187 IPKSSAKPIQPKLGNIP-KASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEG 245
Query: 249 PNKVVPE---QPSRKDHSKPISNPSDNKE--LPKADTNQLADK-GKLSPHAFKTESGEET 302
PE QP D K + KE +PK+ + K G + + +E
Sbjct: 246 DIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEG 305
Query: 303 DLISPPQEEVKSSEPT------EDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENRE 356
D+ P++ ++ E E + PKE D PEE PKE+ S ++ ++E
Sbjct: 306 DIPKSPKQAIQPKEGDIPKSLEEAIPPKEI-DIPKSPEETIQPKEDDSPKSLEEATPSKE 364
Query: 357 GTL 359
G +
Sbjct: 365 GDI 367
Score = 45.8 bits (107), Expect = 8e-05
Identities = 52/241 (21%), Positives = 88/241 (36%), Gaps = 44/241 (18%)
Query: 166 SKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPK--DVPNKSGAEKQTPKDGSNK 223
++ +Q D+P S +D S KS E PK D+P Q+ K+ K
Sbjct: 10 TEESDASQEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPK 69
Query: 224 SGAEEQGPIDG-----------PSKSGAEEQTSKDSPNKV--VPEQPSRKDHSKPISNPS 270
S + P + P + + K S K +P+ P SK P
Sbjct: 70 SSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPK 129
Query: 271 DNKE--------LPKADTNQLADK-GKLSPHAFKTESGEETDLISPPQEEVKSSE----- 316
++E +PK+ + K G ++ + K +E+D+ P+E ++ E
Sbjct: 130 SSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPK 189
Query: 317 -------------PTEDVEPKEAEDDD--TGPEEGSPPKEEKEKMSGSASSENREGTLSD 361
P V+P + ++ D PEE PKE S + + +EG +
Sbjct: 190 SSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPK 249
Query: 362 S 362
S
Sbjct: 250 S 250
Score = 32.7 bits (73), Expect = 0.67
Identities = 38/163 (23%), Positives = 59/163 (36%), Gaps = 33/163 (20%)
Query: 201 QTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRK 260
Q D+P S +D S KS E P +G +P+ P
Sbjct: 17 QEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGD-----------------IPKAPEET 59
Query: 261 DHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTED 320
SK ++LPK+ + K P + + + L + P+ VK S+P E
Sbjct: 60 IQSK-------KEDLPKSSEKAIQPKESNIPKS--SAKPIQPKLGNIPKASVKPSQPKEG 110
Query: 321 VEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDST 363
PK PEE K+E S + + +EG + S+
Sbjct: 111 DIPK-------APEETIQSKKEDLPKSSEEAIQPKEGDIPKSS 146
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 68.9 bits (167), Expect = 8e-12
Identities = 74/336 (22%), Positives = 126/336 (37%), Gaps = 47/336 (13%)
Query: 88 AKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDST------GKSG 141
AK + +G AK K S S SE + ++ + P + + GK+
Sbjct: 61 AKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAA 120
Query: 142 AEAQTPEDSPNRSGAE-AKTQKDSPSKSG--SEAQTTKDVPNKSGADGQTPKDGSSKSGA 198
A+A S S + + QK P + G +A+ K P K+ + S
Sbjct: 121 AKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPP 180
Query: 199 EDQTPKDVPNKSGAE--------KQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPN 250
++Q PK P A+ + PK + K+ + S +EE+ + +P
Sbjct: 181 KNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPK 240
Query: 251 KVVPEQ-------------PSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTE 297
K VP++ P+RK S S+ + +E K N+ + P +
Sbjct: 241 KTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPS--AP 298
Query: 298 SGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPP----------KEEKEKMS 347
+++ PP++ V+ +P E E E D + EE PP K K +
Sbjct: 299 PPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKA 358
Query: 348 GSASSENREGTLSDSTGSEKDDLYPNGSGNGSAESS 383
+SS++ SDS SE D+ +G S+
Sbjct: 359 AESSSDS-----SDSDSSEDDEAPSKPAGTTKNSSN 389
Score = 68.6 bits (166), Expect = 1e-11
Identities = 83/385 (21%), Positives = 146/385 (37%), Gaps = 43/385 (11%)
Query: 30 EAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSS---AEAQTPEDTPNKSGA 86
+ GV+P A P ++ + S E + PK+ K + +AQT P K
Sbjct: 147 QKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTK--APPKPAR 204
Query: 87 EAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQT 146
A K ++ K+ + + + S+S SE + + K+ P+ Q + K+
Sbjct: 205 AAP--KIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTR 262
Query: 147 PEDSPNRSGAEAKTQKDSPSKSG----SEAQTTKDVPNKSGADGQTPK------------ 190
S S ++ + ++ P K+ S P K Q PK
Sbjct: 263 KSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESS 322
Query: 191 -DGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQ------ 243
D S +S + + K P K+ K T K K AE S +E
Sbjct: 323 EDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAG 382
Query: 244 TSKDSPNK--VVPEQPSRKDHSKPISNPSDNKEL--PKADTNQLADKGKLSPHAFKTESG 299
T+K+S NK V + P+ K + P ++L KAD++ ++ S + E
Sbjct: 383 TTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSS----EEEKT 438
Query: 300 EETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTL 359
++ + P+ K++ + + D + + S +EE+EK S SA + +
Sbjct: 439 KKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVA 498
Query: 360 SDSTGSEKDDLYPNGSGNGSAESSH 384
+ S+ P + G AESS+
Sbjct: 499 GGAAPSK-----PASAKKGKAESSN 518
Score = 57.8 bits (138), Expect = 2e-08
Identities = 67/316 (21%), Positives = 126/316 (39%), Gaps = 26/316 (8%)
Query: 25 SVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKS 84
S +EE +P + S+ K Q PK + K ++ ED+ ++S
Sbjct: 271 SSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQ-PVESSEDSSDES 329
Query: 85 GAEAKTQKDSSNKSGAEAKTQK-------GSTSKSGSEAQTTKDSTSKSHPELQTPKDST 137
+ ++ +K K+ T K +S S++ +++D + S P T K+S+
Sbjct: 330 DSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKP-AGTTKNSS 388
Query: 138 GKSGAEAQTPEDSPNRS-------GAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPK 190
K ++P P + G + T+K S S E+ ++++ K PK
Sbjct: 389 NKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPK 448
Query: 191 DGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPN 250
++ A K P S + + D + S EE+ + SKS +++ K +
Sbjct: 449 --ATAKAALSLPAKQAPQGS---RDSSSDSDSSSSEEEE---EKTSKSAVKKKPQKVAGG 500
Query: 251 KVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQE 310
+ S K SN S + + + + +L KGK SP ++ + L + +
Sbjct: 501 AAPSKPASAKKGKAESSNSSSSDDSSEEEEEKL--KGKGSPRPQAPKANGTSALTAQNGK 558
Query: 311 EVKSSEPTEDVEPKEA 326
K+SE E+ + K A
Sbjct: 559 AAKNSEEEEEEKKKAA 574
Score = 56.2 bits (134), Expect = 6e-08
Identities = 54/274 (19%), Positives = 110/274 (40%), Gaps = 10/274 (3%)
Query: 63 PKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDS 122
P + ++E+ + E++ + E + ++ +AK K K+ S + S
Sbjct: 115 PPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSS 174
Query: 123 TSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKS 182
+ P+ Q PK + A+ + P P R+ + K + S S S + ++ D +
Sbjct: 175 SEDEPPKNQKPKITPVTVKAQTKAP-PKPARAAPKIANGKAASSSSSSSSSSSSDDSEEE 233
Query: 183 GADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPI-DGPSKSGAE 241
A TPK K + P + + +D S+ E++ P+ + P +
Sbjct: 234 KA-AATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSV 292
Query: 242 EQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEE 301
S P K + QP +K K P ++ E +++ +++ K P T++
Sbjct: 293 PPPSAPPPKKSLGTQPPKKAVEK--QQPVESSEDSSDESDSSSEEEKKPP----TKAVVS 346
Query: 302 TDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEE 335
PP + K++E + D ++ +DD P +
Sbjct: 347 KATTKPPPAK-KAAESSSDSSDSDSSEDDEAPSK 379
Score = 52.8 bits (125), Expect = 6e-07
Identities = 65/312 (20%), Positives = 122/312 (39%), Gaps = 31/312 (9%)
Query: 54 TKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSG 113
TK+ T K P+K +AE+ + + DSS A +K + + S
Sbjct: 341 TKAVVSKATTKPPPAKKAAESSSD-----------SSDSDSSEDDEAPSKPAGTTKNSSN 389
Query: 114 SEAQTTKDSTSKSHPELQTPKDSTGK---SGAEAQTPEDSPNRSGAEAKTQKDSPSKSGS 170
A TTK K + P K A++ + E+ + S E + + +K +
Sbjct: 390 KPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKA 449
Query: 171 EAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQG 230
A+ +P K G +D SS S + ++ A K+ P+ + +
Sbjct: 450 TAKAALSLPAKQAPQGS--RDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGA------ 501
Query: 231 PIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKAD-TNQL-ADKGK 288
PSK + ++ +S N + S ++ K S + PKA+ T+ L A GK
Sbjct: 502 ---APSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGK 558
Query: 289 LSPHAFKTESGEETDLI----SPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKE 344
+ ++ + E ++ + S ++ K +E ++ E +A+ P +++ E
Sbjct: 559 AAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGE 618
Query: 345 KMSGSASSENRE 356
K + S RE
Sbjct: 619 KRASSPFRRVRE 630
Score = 50.1 bits (118), Expect = 4e-06
Identities = 51/195 (26%), Positives = 77/195 (39%), Gaps = 13/195 (6%)
Query: 24 ESVKQEEAGVRPSA-GNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPN 82
E K+ A +P A + Q P GS S + + + + P
Sbjct: 436 EKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQ 495
Query: 83 KSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGA 142
K A K +S K G +A++ S+S SE + K K P Q PK + G S
Sbjct: 496 KVAGGAAPSKPASAKKG-KAESSNSSSSDDSSEEEEEK-LKGKGSPRPQAPK-ANGTSAL 552
Query: 143 EAQTPEDSPNRSGAEAKTQKDS--PSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAED 200
AQ + + N E + +K + SKSGS K N++ + +TP+ K
Sbjct: 553 TAQNGKAAKNSEEEEEEKKKAAVVVSKSGS---LKKRKQNEAAKEAETPQAKKIKL---- 605
Query: 201 QTPKDVPNKSGAEKQ 215
QTP P + EK+
Sbjct: 606 QTPNTFPKRKKGEKR 620
>gi|16445033 ACRC protein [Homo sapiens]
Length = 691
Score = 67.8 bits (164), Expect = 2e-11
Identities = 65/300 (21%), Positives = 111/300 (37%), Gaps = 29/300 (9%)
Query: 65 DSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTS 124
D+ + + + P+D + S A DS EA S++ + ++
Sbjct: 127 DNDDDNGNDLEVPDDNSDDSEAPDDNSDDS------EAPDDNSDDSEAPDDNSDDSEAPD 180
Query: 125 KSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGA 184
+ + P D++ S + N ++ K S ++ DVP+ S
Sbjct: 181 DNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSD 240
Query: 185 DGQTPKDGSSKSGAEDQTPKD--VPNKSGAEKQTPKDGSNKSGAEEQGPIDGPS---KSG 239
D + P D S S A D + D P+ S + + P D S+ S A + D + S
Sbjct: 241 DSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSD 300
Query: 240 AEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELP------------KADTNQLAD-K 286
E S + VPE S D S + SD+ E+P +D +L +
Sbjct: 301 DSEAPDDKSDDSDVPEDKS--DDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAA 358
Query: 287 GKLSPHAFKTESGEE---TDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEK 343
+S H ++GE+ +L PP + + E +E P E E + G + K
Sbjct: 359 AAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTK 418
Score = 58.9 bits (141), Expect = 9e-09
Identities = 66/333 (19%), Positives = 124/333 (37%), Gaps = 39/333 (11%)
Query: 52 GSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSK 111
G K P Q P++ Q+ D + S + K ++ +++ G TS
Sbjct: 3 GCKKELPRLQEPEEDEDCYILNVQSSSDDTSGSSVARRAPKRQASCI-LNVQSRSGDTSG 61
Query: 112 SGSEAQTTKDSTSK-------SHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKD- 163
S + K S S E T ++ K E + ++SP + Q+
Sbjct: 62 SSVARRAPKRQASSVVVIDSDSDEECHTHEEKKAKL-LEINSDDESPECCHVKPAIQEPP 120
Query: 164 ---SPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKD--VPNKSGAEKQTPK 218
S + + +VP+ + D + P D S S A D D P+ + + + P
Sbjct: 121 IVISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPD 180
Query: 219 DGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELP-- 276
D S+ S + D S +++ + +S + VP+ S D S + SD+ ++P
Sbjct: 181 DNSDDSDVPDDNS-DDSSDDNSDDSSDDNSDDSDVPDDKS--DDSDVPDDSSDDSDVPDD 237
Query: 277 KADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEG 336
+D ++ D + +D P + SE P ++ DD P++
Sbjct: 238 SSDDSEAPD--------------DSSDDSEAPDDSSDDSEA-----PDDSSDDSEAPDDS 278
Query: 337 SPPKEEKEKMSGSASSENREGTLSDSTGSEKDD 369
S E + S + + + S++ + DD
Sbjct: 279 SDDSEASDDSSDDSEASDDSSDDSEAPDDKSDD 311
Score = 55.5 bits (132), Expect = 1e-07
Identities = 65/318 (20%), Positives = 123/318 (38%), Gaps = 45/318 (14%)
Query: 53 STKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKS 112
S S + D P S ++ P+D S ++ DSS+ S A S
Sbjct: 201 SDDSSDDNSDDSDVPDDKSDDSDVPDD----SSDDSDVPDDSSDDSEA--------PDDS 248
Query: 113 GSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEA 172
+++ DS+ S + P DS+ +++ P+DS + S EA S++ ++
Sbjct: 249 SDDSEAPDDSSDDS----EAPDDSSD----DSEAPDDSSDDS--EASDDSSDDSEASDDS 298
Query: 173 QTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPI 232
+ P+ D P+D S S DVP+ + + + P + E Q
Sbjct: 299 SDDSEAPDDKSDDSDVPEDKSDDS--------DVPDDNSDDLEVPVPAEDLCN-EGQIAS 349
Query: 233 DGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPH 292
D A S+ + EQ ++ SKP S+P N E+ + + +
Sbjct: 350 DEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQ 409
Query: 293 AFKTESGEET-------------DLISPPQE-EVKSSEPTEDVEPKEAEDDDTGPEEGSP 338
+ K +S +T +++ PP++ + K+ E + ++A+ + G
Sbjct: 410 SGKRKSKTKTIVEPPRKRQTKTKNIVEPPRKRQTKTKNIVEPLRKRKAKTKNVSVTPGHK 469
Query: 339 PKEEKEKMSGSASSENRE 356
+ +K G+A E R+
Sbjct: 470 KRGPSKKKPGAAKVEKRK 487
Score = 53.5 bits (127), Expect = 4e-07
Identities = 66/311 (21%), Positives = 116/311 (37%), Gaps = 51/311 (16%)
Query: 61 QTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEA-----KTQKGST----SK 111
Q+ D S SS + P+ ++ Q S + SG+ K Q S S
Sbjct: 26 QSSSDDTSGSSVARRAPK---RQASCILNVQSRSGDTSGSSVARRAPKRQASSVVVIDSD 82
Query: 112 SGSEAQTTKDSTSKS---------------HPELQTPK------DSTGKSGAEAQTPEDS 150
S E T ++ +K P +Q P D+ +G + + P+D
Sbjct: 83 SDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDD- 141
Query: 151 PNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKS 210
N +EA S++ + + P+ + D + P D S S D N
Sbjct: 142 -NSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDD------NSD 194
Query: 211 GAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPS 270
+ D S+ + + P D S + +S DS VP+ S D S+ + S
Sbjct: 195 DSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSD---VPDDSS--DDSEAPDDSS 249
Query: 271 DNKELP--KADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTED--VEPKEA 326
D+ E P +D ++ D A +S ++++ ++ ++S+ + D P +
Sbjct: 250 DDSEAPDDSSDDSEAPDDSSDDSEA-PDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDK 308
Query: 327 EDDDTGPEEGS 337
DD PE+ S
Sbjct: 309 SDDSDVPEDKS 319
Score = 52.0 bits (123), Expect = 1e-06
Identities = 57/256 (22%), Positives = 97/256 (37%), Gaps = 25/256 (9%)
Query: 121 DSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPN 180
D+ + +L+ P D++ S A P+D N +EA S++ + + P+
Sbjct: 127 DNDDDNGNDLEVPDDNSDDSEA----PDD--NSDDSEAPDDNSDDSEAPDDNSDDSEAPD 180
Query: 181 KSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQG------PIDG 234
+ D P D S S D D + + + P D S+ S + P D
Sbjct: 181 DNSDDSDVPDDNSDDSS--DDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDS 238
Query: 235 PSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELP--KADTNQLADKGKLSPH 292
S A + +S DS P+ S D S+ + SD+ E P +D ++ +D
Sbjct: 239 SDDSEAPDDSSDDSE---APDDSS--DDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSE 293
Query: 293 AFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASS 352
A S + +D P ++ S+ ED DD + P E G +S
Sbjct: 294 A----SDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIAS 349
Query: 353 ENREGTLSDSTGSEKD 368
+ E + + S+ D
Sbjct: 350 DEEELVEAAAAVSQHD 365
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 65.1 bits (157), Expect = 1e-10
Identities = 77/358 (21%), Positives = 136/358 (37%), Gaps = 29/358 (8%)
Query: 47 SQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQK 106
S++ GGS ++PE + + +K EA + TP KS E + K S + S ++Q
Sbjct: 131 SKKKGGSYATNPESKQIVEEKTKRQNEA---DKTPLKSSHENEQSKKSKSSSETNPESQN 187
Query: 107 GSTSKSGSEAQTTKDS--TSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDS 164
T + KDS + K++ E K++ K ++T D + +E D
Sbjct: 188 SKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDF 247
Query: 165 PSKSGS--------EAQTTKDVPNKSG---------ADGQTPKDGSSKSGAEDQTPKDVP 207
G +A N S T K+ S AE + KD
Sbjct: 248 LMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAK 307
Query: 208 NKS-GAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSK-P 265
S +K KD K ++ D S +E+ K + + +KD K P
Sbjct: 308 KDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYP 367
Query: 266 ISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKE 325
S +++ + A N + K S + K + ++ + + E++S E +D E K+
Sbjct: 368 ESTDTESGDAKDA-RNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKD-EKKD 425
Query: 326 AEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTG---SEKDDLYPNGSGNGSA 380
+D T ++ EE ++++G + G S+KDD + N +
Sbjct: 426 KKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAES 483
Score = 48.1 bits (113), Expect = 2e-05
Identities = 62/304 (20%), Positives = 127/304 (41%), Gaps = 17/304 (5%)
Query: 57 HPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEA 116
+ + T K++ S AE++ +D S K K K + T+ + ++SG
Sbjct: 283 YTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTES-TDAESGDSK 341
Query: 117 QTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPS-KSGSEAQTT 175
KD T K +L+ KD K + PE + SG + DS + K S+
Sbjct: 342 DERKD-TKKDKKKLK--KDDKKKD--TKKYPESTDTESGDAKDARNDSRNLKKASKNDDK 396
Query: 176 KDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGP 235
K K + + SK +D+ KD + K++ K+ + A+ + G
Sbjct: 397 KKDAKKITFSTDSESELESKESQKDE-KKDKKDSKTDNKKSVKNDEESTDADSEP--KGD 453
Query: 236 SKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFK 295
SK G +++ +K ++ K +++ SD EL K + KG S K
Sbjct: 454 SKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESD-LELKKDKKHSKEKKG--SKKDIK 510
Query: 296 TESGEETDLISPPQEEVKSS--EPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSE 353
++ ++T+ +E + + + ++ + E +++ + G+ K++ ++ G++++
Sbjct: 511 KDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGA--KKKIDESDGTSANS 568
Query: 354 NREG 357
EG
Sbjct: 569 KMEG 572
Score = 47.4 bits (111), Expect = 3e-05
Identities = 62/296 (20%), Positives = 110/296 (37%), Gaps = 38/296 (12%)
Query: 90 TQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPED 149
T+K++ S AE++ K + S + K + K + KD+ + ++
Sbjct: 288 TKKNAKKSSDAESEDSKDAKKDS----KKVKKNVKKDDKKKDVKKDTESTDAESGDSKDE 343
Query: 150 SPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNK 209
+ + K +KD K TK P + + KD + S + K+ K
Sbjct: 344 RKDTKKDKKKLKKDDKKKD------TKKYPESTDTESGDAKDARNDSRNLKKASKNDDKK 397
Query: 210 SGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNP 269
A+K T + + ++ E++ KD S+ D+ K + N
Sbjct: 398 KDAKKIT-------FSTDSESELESKESQKDEKKDKKD----------SKTDNKKSVKND 440
Query: 270 SDNKEL---PKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEA 326
++ + PK D+ KGK K +S ++ D ++ +S+E D+E K
Sbjct: 441 EESTDADSEPKGDSK----KGKKDEKKGKKDS-KKDDKKKDAKKNAESTEMESDLELK-- 493
Query: 327 EDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAES 382
+D E+ K+ K+ S + E S TG K GS S ES
Sbjct: 494 KDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGF-KTSTKIKGSDTESEES 548
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 65.1 bits (157), Expect = 1e-10
Identities = 80/336 (23%), Positives = 128/336 (38%), Gaps = 39/336 (11%)
Query: 64 KDSPSKSSAEAQTPEDTP---------NKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGS 114
+DS + + P TP N GA+ ++ DSS+ SG+E+ + S S+S S
Sbjct: 390 EDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGAD-NSRDDSSSHSGSESSSGSDSESESSS 448
Query: 115 EAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQT 174
+ + + PE + P T K + + +P++ + + PS G + +
Sbjct: 449 SDSEANEPSQSASPEPEPPP--TNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEG 506
Query: 175 TKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSG------------------AEKQT 216
+ S D PK+ SS + D ++SG K+
Sbjct: 507 REQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQ 566
Query: 217 PKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELP 276
PK + E +G + S++ + +S S + SRK + K S S P
Sbjct: 567 PKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPR---P 623
Query: 277 KADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEG 336
A+ + K S K+ ETD S +E +S P+ PK E + T P +
Sbjct: 624 TAEKKKYKSTSKSSQ---KSREIIETDTSSSDSDESESLPPSSQT-PKYPESNRT-PVKP 678
Query: 337 SPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYP 372
S +EE S E L S SE DD YP
Sbjct: 679 SSVEEEDSFFRQRMFSPMEEKELL-SPLSEPDDRYP 713
Score = 60.8 bits (146), Expect = 2e-09
Identities = 76/339 (22%), Positives = 130/339 (38%), Gaps = 30/339 (8%)
Query: 54 TKSHPEPQTPKDSPSKSSAEA---QTPEDTPNKSGA-EAKTQKDSSNKSGAEAKTQ---- 105
T S P P T +P K+ T E + G E K S +G ++K+
Sbjct: 324 THSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDD 383
Query: 106 -KGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDS 164
K S+S+ Q + +S P + GA+ + +DS + SG+E+ + DS
Sbjct: 384 LKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGAD-NSRDDSSSHSGSESSSGSDS 442
Query: 165 PSKSGSE-------AQTTKDVP-----NKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGA 212
S+S S +Q+ P NK D K K ++P+ G
Sbjct: 443 ESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGY 502
Query: 213 EKQTPKDGSNKSGAEEQGPIDGPSKS-GAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSD 271
+K+ + G+ S + GP + S + G + +T + Q S +
Sbjct: 503 KKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTV 562
Query: 272 NKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDT 331
K+ PK A++ + K ES DL S + +P ++ +
Sbjct: 563 GKKQPKKAEKAAAEEPR---GGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKS 619
Query: 332 GPEEGSPPKEEKEKMSGSASSE-NREGTLSDSTGSEKDD 369
P P E+K+ S S SS+ +RE +D++ S+ D+
Sbjct: 620 SPR---PTAEKKKYKSTSKSSQKSREIIETDTSSSDSDE 655
Score = 54.7 bits (130), Expect = 2e-07
Identities = 84/361 (23%), Positives = 134/361 (37%), Gaps = 38/361 (10%)
Query: 40 VSTHPSLSQ---RPGGSTKSHPEPQTPKDSPSKSSAEAQTPE-DTPNKSGAEAKTQ---- 91
V PS SQ R G H +T S S +++ Q + ++ N SG+ ++ +
Sbjct: 111 VGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHG 170
Query: 92 -KDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDS 150
+ S ++S + K Q S+ S D SK H ++P+D + ++ P S
Sbjct: 171 SEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSS 230
Query: 151 PNRSGAEAKTQKDSP---SKSGSEAQ-TTKDVPNKSGADGQTPK----DGSSKSGAEDQT 202
S TQ P SKS S Q T V G + PK SS+S T
Sbjct: 231 GQHS-----TQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMT 285
Query: 203 PKDVPNKSGAEK-QTPKDGSNKSGAEEQGPIDGPSK----SGAEEQTSKDSPNKVVPEQ- 256
+K+ K + P + S + + +D K S T+ +P K P +
Sbjct: 286 ELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKF 345
Query: 257 --PSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKS 314
P+++ + P +N K L K S E++D + +
Sbjct: 346 PFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDD-LKLSSSEDSDGEQDCDKTMPR 404
Query: 315 SEPTEDVEP----KEAED---DDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEK 367
S P + EP E D DD+ GS + S S+SS++ S S E
Sbjct: 405 STPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEP 464
Query: 368 D 368
+
Sbjct: 465 E 465
Score = 50.1 bits (118), Expect = 4e-06
Identities = 74/341 (21%), Positives = 128/341 (37%), Gaps = 43/341 (12%)
Query: 49 RPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKT-QKDSSNKSGAEAKTQKG 107
R G+ S+ + PK++ S TP G ++KT QK S + G +
Sbjct: 507 REQGTGNSYTDTSGPKETSS------ATP-------GRDSKTIQKGSESGRGRQ------ 547
Query: 108 STSKSGSEAQTTKDSTSKSHP---ELQTPKDSTGKSGAEAQTPED--SPNRSGAEAKTQK 162
S + S++ T + + K P E ++ G E++TP D S S K
Sbjct: 548 -KSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATK 606
Query: 163 DSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSN 222
S + + + P ++ S KS +T + +E P +
Sbjct: 607 GSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTP 666
Query: 223 KSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKEL-PKADTN 281
K + P+ S EE+ S P + K+ P+S P D L K D N
Sbjct: 667 KYPESNRTPV---KPSSVEEEDSFFRQRMFSPME--EKELLSPLSEPDDRYPLIVKIDLN 721
Query: 282 QLADKGKLSPHAFKTESGEETDLISPPQEEVK------SSEPTEDVEPKEAEDDDTGPEE 335
L ++ +K + + + P++ + S + + + K +DD E
Sbjct: 722 LLT---RIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASE 778
Query: 336 GSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSG 376
PK E + +G S NRE S + +++ DL P+ +G
Sbjct: 779 SKKPKTEDKNSAGHKPSSNRES--SKQSAAKEKDLLPSPAG 817
Score = 48.9 bits (115), Expect = 9e-06
Identities = 78/345 (22%), Positives = 128/345 (37%), Gaps = 45/345 (13%)
Query: 47 SQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQK 106
++ P G K E +TP D S S ++ T K + SS + AE K K
Sbjct: 575 AEEPRGGLKI--ESETPVDLAS-SMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYK 631
Query: 107 GSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPS 166
STSKS + KS ++T S+ +E+ P + +T P
Sbjct: 632 -STSKS----------SQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRT----PV 676
Query: 167 KSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTP----------KDVPNKSGAEKQT 216
K S + + + + + S S +D+ P +P K E +
Sbjct: 677 KPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEP 736
Query: 217 PKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELP 276
PK G K+ E+ A++Q S+ NK RK ++ + S++K+
Sbjct: 737 PK-GEKKNVPEKH-------TREAQKQASEKVSNK-----GKRKHKNEDDNRASESKKPK 783
Query: 277 KADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEP-TEDVEPKEAEDDDTGPEE 335
D N K + + K + +E DL+ P V S +P TE K + +
Sbjct: 784 TEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKS 843
Query: 336 GSPPKEE---KEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGN 377
S +E K S S S + + + S+ E + P+ S N
Sbjct: 844 SSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSN 888
Score = 45.8 bits (107), Expect = 8e-05
Identities = 43/183 (23%), Positives = 77/183 (42%), Gaps = 10/183 (5%)
Query: 46 LSQRPGGSTKSHPEPQTPKDS-PSKSSAEAQ--TPEDTPNKSGAEAKTQKDSSNKSGAEA 102
L++ PG K P+ K + P K + EAQ E NK + K + D+ +
Sbjct: 723 LTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKP 782
Query: 103 KTQKGSTS--KSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKT 160
KT+ +++ K S +++K S +K L +P + +T S R+ +++ +
Sbjct: 783 KTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPV--PSKDPKTEHGSRKRTISQSSS 840
Query: 161 QKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDG 220
K S S S +T+ N S Q +G + S +++ K + S P
Sbjct: 841 LK---SSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLD 897
Query: 221 SNK 223
S+K
Sbjct: 898 SSK 900
Score = 31.6 bits (70), Expect = 1.5
Identities = 32/138 (23%), Positives = 59/138 (42%), Gaps = 14/138 (10%)
Query: 22 ATESVK-----QEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQT 76
A+ES K + AG +PS+ S+ S ++ P P P PSK + +T
Sbjct: 776 ASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKD----LLPSPAGP--VPSK---DPKT 826
Query: 77 PEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDS 136
+ ++ +++ + K SSN + + + K S+S S + K S+S + + P S
Sbjct: 827 EHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSS 886
Query: 137 TGKSGAEAQTPEDSPNRS 154
+ + P R+
Sbjct: 887 SNCPPSAPTLDSSKPRRT 904
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 64.3 bits (155), Expect = 2e-10
Identities = 81/371 (21%), Positives = 145/371 (39%), Gaps = 35/371 (9%)
Query: 53 STKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNK----SGAEAKTQKGS 108
S +S P+ Q + S E + +K TQ+ S + G++ ++ G
Sbjct: 147 SEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGD 206
Query: 109 TSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKS 168
S+ E + D S + +S G E+ + N + + PS+
Sbjct: 207 GSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRK 266
Query: 169 GSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDV---PNKSGAEKQTPKDGSNKSG 225
+ ++S D + E+ +D + ++ + +D
Sbjct: 267 IFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLS 326
Query: 226 AEEQGPIDGPSKSGAEE------QTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKAD 279
EE +DGPS ++E + S +S +VV E SR D+ P ++ +++E +D
Sbjct: 327 QEESQNVDGPSSESSQEANLSSQENSSESQEEVVSE--SRGDNPDPTTSYVEDQE--DSD 382
Query: 280 TNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVE--PKEAEDDDTGPEEG- 336
+++ LS H+ K+ES EE Q + +SSE E P+ ED+++ +EG
Sbjct: 383 SSEEDSSHTLS-HS-KSESREE-------QADSESSESLNFSEESPESPEDENSSSQEGL 433
Query: 337 SPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAESSHFFAYLVTAAILV 396
E S + SE + DS+ S++D + S SS L I
Sbjct: 434 QSHSSSAESQSEESHSEEDDSDSQDSSRSKED-----SNSTESKSSSEEDGQLKNIEIES 488
Query: 397 AVLYI-AHHNK 406
L + A+HNK
Sbjct: 489 RKLTVDAYHNK 499
Score = 53.5 bits (127), Expect = 4e-07
Identities = 80/419 (19%), Positives = 162/419 (38%), Gaps = 51/419 (12%)
Query: 11 NVAAAGAVPLLATESVK------QEEAGVRPSAGNVST-------HPSLSQRPGGSTKSH 57
++A A PL ++ES + +E+A PS S H + + GG ++S
Sbjct: 36 HLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRST 95
Query: 58 PEPQTPKDSPSKSSAEAQTPEDTPN------KSGAEAKTQKDSSNKSGAEAKTQKGSTSK 111
+ KD S + +D + G ++ D + +A + +
Sbjct: 96 GKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQ 155
Query: 112 SGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPE---------DSPNRSGAEAKT-- 160
++ TT +S + + K G S E+++ E +S + G+E
Sbjct: 156 DSAQ-DTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEG 214
Query: 161 -QKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDV---PNKSGAEKQT 216
Q D P SE ++ N +G + + S ++ +D + P++ K
Sbjct: 215 MQSDDPESIRSERGNSR--MNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSR 272
Query: 217 PKDGSNKSGAEEQGPIDGPSKSGAEEQTSKD---SPNKVVPEQPSRKDHSKPISNP-SDN 272
+ ++S ++ ++ E S+D S + + S++D + +S S N
Sbjct: 273 ISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQN 332
Query: 273 KELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTG 332
+ P ++++Q A+ LS +ES EE S ++ ED E ++ ++D+
Sbjct: 333 VDGPSSESSQEAN---LSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSS 389
Query: 333 PEEGSPPKEEKEKMSGSASS-------ENREGTLSDSTGSEKDDLYPNGSGNGSAESSH 384
E +E+ + S SS E+ E +++ S++ + S +E SH
Sbjct: 390 HTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESH 448
Score = 46.2 bits (108), Expect = 6e-05
Identities = 53/253 (20%), Positives = 99/253 (39%), Gaps = 38/253 (15%)
Query: 40 VSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSG 99
+S S+ +T + + ++S S+ + +Q D+ S ++K N S
Sbjct: 273 ISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSK-----ENLSQ 327
Query: 100 AEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAK 159
E++ G +S+S EA + S E + +S G D+P+ + + +
Sbjct: 328 EESQNVDGPSSESSQEANLSSQENSSESQE-EVVSESRG----------DNPDPTTSYVE 376
Query: 160 TQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAED--QTPKDVPNKSGAEKQTP 217
Q+DS S + T ++S + + S + +E+ ++P+D N S E
Sbjct: 377 DQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPED-ENSSSQEGLQS 435
Query: 218 KDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKD---------------- 261
S +S +EE + S S + SK+ N + S +D
Sbjct: 436 HSSSAESQSEESHSEEDDSDS-QDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVD 494
Query: 262 --HSKPISNPSDN 272
H+KPI + DN
Sbjct: 495 AYHNKPIGDQDDN 507
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 64.3 bits (155), Expect = 2e-10
Identities = 81/371 (21%), Positives = 145/371 (39%), Gaps = 35/371 (9%)
Query: 53 STKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNK----SGAEAKTQKGS 108
S +S P+ Q + S E + +K TQ+ S + G++ ++ G
Sbjct: 131 SEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGD 190
Query: 109 TSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKS 168
S+ E + D S + +S G E+ + N + + PS+
Sbjct: 191 GSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRK 250
Query: 169 GSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDV---PNKSGAEKQTPKDGSNKSG 225
+ ++S D + E+ +D + ++ + +D
Sbjct: 251 IFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLS 310
Query: 226 AEEQGPIDGPSKSGAEE------QTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKAD 279
EE +DGPS ++E + S +S +VV E SR D+ P ++ +++E +D
Sbjct: 311 QEESQNVDGPSSESSQEANLSSQENSSESQEEVVSE--SRGDNPDPTTSYVEDQE--DSD 366
Query: 280 TNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVE--PKEAEDDDTGPEEG- 336
+++ LS H+ K+ES EE Q + +SSE E P+ ED+++ +EG
Sbjct: 367 SSEEDSSHTLS-HS-KSESREE-------QADSESSESLNFSEESPESPEDENSSSQEGL 417
Query: 337 SPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAESSHFFAYLVTAAILV 396
E S + SE + DS+ S++D + S SS L I
Sbjct: 418 QSHSSSAESQSEESHSEEDDSDSQDSSRSKED-----SNSTESKSSSEEDGQLKNIEIES 472
Query: 397 AVLYI-AHHNK 406
L + A+HNK
Sbjct: 473 RKLTVDAYHNK 483
Score = 55.8 bits (133), Expect = 7e-08
Identities = 77/334 (23%), Positives = 129/334 (38%), Gaps = 53/334 (15%)
Query: 43 HPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDT--PNKSGAEAKTQKDSSNKSGA 100
H + + GG ++S T K K E + +DT + SG K +++ N
Sbjct: 65 HQYIYRLAGGFSRS-----TGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGN---- 115
Query: 101 EAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKT 160
++ GS S Q +++S + Q D+T +S + N ++K
Sbjct: 116 ---SRLGSDEDSDDTIQASEESAPQGQDSAQ---DTTSES-------RELDNEDRVDSKP 162
Query: 161 Q-KDSPSKSGSEAQTTKDVPNKSGADGQTPK-DGS--SKSGAEDQTPKDVPNKSGAEKQT 216
+ DS +S SE G+DG++ DGS G + P+ + ++ G +
Sbjct: 163 EGGDSTQESESEEHWV-----GGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMN 217
Query: 217 PKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKP-ISNPSDNKEL 275
+K E +E+ ++DS + E PSRK K IS D EL
Sbjct: 218 SAGMKSKESGE-----------NSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSEL 266
Query: 276 PKADTNQLADKGKLSPHAFKTESGEETDL-ISPPQEEVKSSEPTEDVEPKEAEDDDTGPE 334
D N ++ K + TE+ D +S P+ + K + E E+
Sbjct: 267 ---DDNNTMEEVK----SDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDG 319
Query: 335 EGSPPKEEKEKMSGSASSENREGTLSDSTGSEKD 368
S +E S SSE++E +S+S G D
Sbjct: 320 PSSESSQEANLSSQENSSESQEEVVSESRGDNPD 353
Score = 50.8 bits (120), Expect = 2e-06
Identities = 71/366 (19%), Positives = 142/366 (38%), Gaps = 35/366 (9%)
Query: 45 SLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKT 104
S S GG K E + D+ + P+D + + +DS + A +
Sbjct: 76 SRSTGKGGDDKDDDEDDSGDDTFGDDDS-GPGPKDRQEGGNSRLGSDEDSDDTIQA---S 131
Query: 105 QKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPE---------DSPNRSG 155
++ + S TT +S + + K G S E+++ E +S + G
Sbjct: 132 EESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDG 191
Query: 156 AEAKT---QKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDV---PNK 209
+E Q D P SE ++ N +G + + S ++ +D + P++
Sbjct: 192 SELDDEGMQSDDPESIRSERGNSR--MNSAGMKSKESGENSEQANTQDSGGSQLLEHPSR 249
Query: 210 SGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKD---SPNKVVPEQPSRKDHSKPI 266
K + ++S ++ ++ E S+D S + + S++D + +
Sbjct: 250 KIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENL 309
Query: 267 SNP-SDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKE 325
S S N + P ++++Q A+ LS +ES EE S ++ ED E +
Sbjct: 310 SQEESQNVDGPSSESSQEAN---LSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSD 366
Query: 326 AEDDDTGPEEGSPPKEEKEKMSGSASS-------ENREGTLSDSTGSEKDDLYPNGSGNG 378
+ ++D+ E +E+ + S SS E+ E +++ S++ + S
Sbjct: 367 SSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAES 426
Query: 379 SAESSH 384
+E SH
Sbjct: 427 QSEESH 432
Score = 46.2 bits (108), Expect = 6e-05
Identities = 53/253 (20%), Positives = 99/253 (39%), Gaps = 38/253 (15%)
Query: 40 VSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSG 99
+S S+ +T + + ++S S+ + +Q D+ S ++K N S
Sbjct: 257 ISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSK-----ENLSQ 311
Query: 100 AEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAK 159
E++ G +S+S EA + S E + +S G D+P+ + + +
Sbjct: 312 EESQNVDGPSSESSQEANLSSQENSSESQE-EVVSESRG----------DNPDPTTSYVE 360
Query: 160 TQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAED--QTPKDVPNKSGAEKQTP 217
Q+DS S + T ++S + + S + +E+ ++P+D N S E
Sbjct: 361 DQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPED-ENSSSQEGLQS 419
Query: 218 KDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKD---------------- 261
S +S +EE + S S + SK+ N + S +D
Sbjct: 420 HSSSAESQSEESHSEEDDSDS-QDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVD 478
Query: 262 --HSKPISNPSDN 272
H+KPI + DN
Sbjct: 479 AYHNKPIGDQDDN 491
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 63.2 bits (152), Expect = 5e-10
Identities = 76/340 (22%), Positives = 142/340 (41%), Gaps = 39/340 (11%)
Query: 50 PGGS----------TKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSG 99
PGGS T S + QTP PSK ++ +P + ++ Q ++
Sbjct: 199 PGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRK---VKSYGQMIIPSREK 255
Query: 100 AEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPED------SPNR 153
+ + T+ S KS ++A T S +SH + ++P+ S +SG++ +T N
Sbjct: 256 SYSPTEMSSRVKSYNQASTR--SRPQSHSQSRSPRRS--RSGSQKRTHSRVRSHSWKRNH 311
Query: 154 SGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAE 213
S A ++T+K S+ G +Q+ KS +TP+ G S + + + + + + S +
Sbjct: 312 SRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSS 371
Query: 214 KQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSR-----KDHSKPISN 268
+ + S +E G S + + + SPNK SR +D S+ S
Sbjct: 372 SKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRS- 430
Query: 269 PSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAED 328
P+ ++ ++ + A S K + + ++ +S P+++ + +
Sbjct: 431 PNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQL-- 488
Query: 329 DDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKD 368
GSP KE + S S S E R+ S S+ E+D
Sbjct: 489 -------GSPSKERDHRRSRSPSKE-RQCRQSRSSSKERD 520
Score = 58.9 bits (141), Expect = 9e-09
Identities = 73/375 (19%), Positives = 154/375 (41%), Gaps = 39/375 (10%)
Query: 24 ESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNK 83
+S Q RP + + S P S R G ++H ++ + S A ++T + ++
Sbjct: 267 KSYNQASTRSRPQSHSQSRSPRRS-RSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQ 325
Query: 84 SGAEAKTQKDSSNKSGAEAKTQKG--------STSKSGSEAQTTKDSTSKSHPELQTPKD 135
G ++++ S KS +++T + + SK S + + S + H +P+
Sbjct: 326 MGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRK 385
Query: 136 STGKSGAEAQTPED------SPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTP 189
+G+S + + + SPN++ ++++ ++ S +++ PNK+ +
Sbjct: 386 ESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRS----PNKA----RDC 437
Query: 190 KDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSP 249
S A D++ PNK A + NK A ++ PSK + + SP
Sbjct: 438 SRSRSPYKARDRSRSRSPNK--ARDHSRSRSPNK--ARDRSRSRSPSKE--RDHSQLGSP 491
Query: 250 NKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQ 309
+K +DH + S PS ++ ++ ++ + S K ++ + +
Sbjct: 492 SK-------ERDHRRSRS-PSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKER 543
Query: 310 EEVKSSEPTEDVEPKEAE--DDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEK 367
+ +S P+E+ E +++ + P +E+E+ +SSE R+ + S S +
Sbjct: 544 DRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQS 603
Query: 368 DDLYPNGSGNGSAES 382
P S A S
Sbjct: 604 GYSRPRASSKEKAHS 618
Score = 47.0 bits (110), Expect = 3e-05
Identities = 47/251 (18%), Positives = 96/251 (38%), Gaps = 15/251 (5%)
Query: 49 RPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGS 108
R + H ++P + +S + + + E ++ G+ +K + ++S ++ + + S
Sbjct: 453 RSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQS 512
Query: 109 TSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTP-EDSPNRSGAEAKTQKD---- 163
S S S SK Q+ + + +++++P E+ +R ++D
Sbjct: 513 RSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRW 572
Query: 164 -SPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSN 222
SPSK Q+ + + ++P S S + + K+ + +TP N
Sbjct: 573 RSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKE----KAHSRSRTPSKEGN 628
Query: 223 KSGAEEQGPIDGPSKSGAEEQTS-KDSPNKVVP----EQPSRKDHSKPISNPSDNKELPK 277
S + PS+S K SP + PS+ P + PS + L +
Sbjct: 629 HSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQ 688
Query: 278 ADTNQLADKGK 288
D+ A K
Sbjct: 689 DDSQADATTSK 699
Score = 45.1 bits (105), Expect = 1e-04
Identities = 62/300 (20%), Positives = 108/300 (36%), Gaps = 50/300 (16%)
Query: 41 STHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAK-------TQKD 93
S+ PS+S P GS+ +P+ P S SA TPN+S K
Sbjct: 7 SSKPSMSLAPSGSSMPTADPKPPASLKSTKSA-------TPNRSLVPTKPATSRNSVMSP 59
Query: 94 SSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSG-----------A 142
SS+KS T++ +++ S ++ + + S T K+ +
Sbjct: 60 SSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHS 119
Query: 143 EAQTPEDSPNRSGAEAKTQKDSP-------SKSGSEAQTTKDVPNKSGADGQT-PKDGSS 194
+TP +RS + ++ +P ++ G ++ + G+ G++ + +S
Sbjct: 120 RGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTS 179
Query: 195 KSGAEDQTPKDVPNKSGAEKQTPKDGS----------NKSGAEEQGPIDGPSKSGAEEQT 244
D P+++ KS P GS S A+ Q P PSK ++ +
Sbjct: 180 NRERSDSQPRNLSKKS----YRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPS 235
Query: 245 SKDSPNKVVPEQ---PSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEE 301
S Q PSR+ P S K +A T S ++ SG +
Sbjct: 236 PSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQ 295
Score = 43.1 bits (100), Expect = 5e-04
Identities = 64/353 (18%), Positives = 133/353 (37%), Gaps = 41/353 (11%)
Query: 20 LLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPED 79
L+ T+ + + PS+ + S + P S ++ +PS+ S + +T +
Sbjct: 44 LVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKA 103
Query: 80 TPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSH-------PELQT 132
+ ++ + + S ++GS S S ++ + ++H ++T
Sbjct: 104 S---KASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRT 160
Query: 133 P----KDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQT 188
P K S GKS +T ++ S S+ + ++ + P SG G++
Sbjct: 161 PTSQQKGSRGKSYGRPRT------------SNRERSDSQPRNLSKKSYRPPGGSGI-GRS 207
Query: 189 PKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDS 248
+ + S A+ QTP +P+K ++ +P S+ + G + PS+ + T S
Sbjct: 208 SELAVTPSTAKCQTPTGIPSKEKSDNPSP---SSSRKVKSYGQMIIPSREKSYSPTEMSS 264
Query: 249 PNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFK-----TESGEETD 303
K + +R S+P S+ +Q ++ H++K S
Sbjct: 265 RVKSYNQASTR---SRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKG 321
Query: 304 LISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEG---SPPKEEKEKMSGSASSE 353
++S +S ++ ++ G +P KE S S+S E
Sbjct: 322 ILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKE 374
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 63.2 bits (152), Expect = 5e-10
Identities = 81/323 (25%), Positives = 135/323 (41%), Gaps = 51/323 (15%)
Query: 75 QTPEDTPNKSGAEAK-TQKDSSNKSGAEAKTQKGSTSKS---GSEAQTTKDSTSKSHPEL 130
+T D ++G + K +K S+ SG++ T+KG ++KS + + T+ +S EL
Sbjct: 724 KTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSEL 783
Query: 131 QTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNK---SGADGQ 187
+ S K GA T + PN ++ ++ + SK G + Q K++ S D +
Sbjct: 784 EKEIKSMSKIGAARTTKKRIPNTKDFDS-SEDEKHSKKGMDNQGHKNLKTSQEGSSDDAE 842
Query: 188 TPKDGSSKSGAEDQTPKD---------VPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKS 238
++ + S AE KD +P K A T DG +K +EQ +
Sbjct: 843 RKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASAST--DGVDKLSGKEQSFTSLEVRK 900
Query: 239 GAE-EQTSKDSPNKV----------VPEQPSRKDHSKPISNPSDNKELPKADTNQLADKG 287
AE ++ SK K + E+ +KD S S D+K+ K T +
Sbjct: 901 VAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETS--EDDKKQSKKGTEE----- 953
Query: 288 KLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMS 347
K P FK + +I Q+ SS+ TE + +E E PK K+ +
Sbjct: 954 KKKPSDFKKK------VIKMEQQYESSSDGTEKLPERE--------EICHFPKGIKQIKN 999
Query: 348 GSASSENREGTLSDSTGSEKDDL 370
G+ E + + D T +KD+L
Sbjct: 1000 GTTDGEKKSKKIRDKTSKKKDEL 1022
Score = 52.0 bits (123), Expect = 1e-06
Identities = 75/311 (24%), Positives = 112/311 (36%), Gaps = 57/311 (18%)
Query: 64 KDSPSKSSAEAQTPEDTPNKSG-AEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQ----- 117
K + SS+ + +D N G + QK + G SG EA
Sbjct: 1158 KQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVP 1217
Query: 118 -TTKDSTSKSHPELQTPKD----------STGKSGAEAQTPEDSPNRSGA---------E 157
T D + PE + K S+ + G+ PE+ R+G E
Sbjct: 1218 VTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEE 1277
Query: 158 AKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQT- 216
AK Q +S S S SE ++ T DG +SG EK+T
Sbjct: 1278 AKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDG----------------ESGEEKKTK 1321
Query: 217 PKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSR-KDHSKPISNPSDNKEL 275
PK+ G + K +E+ D V E+ S +D +P + + EL
Sbjct: 1322 PKEHKEVKGRNRR-------KVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL 1374
Query: 276 PKADTNQLADKGKLSPHAFKTE--SGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGP 333
+ NQ + K K K + S E S +EE K E E+ E +E E++D
Sbjct: 1375 ---EENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEE-EEEDEND 1430
Query: 334 EEGSPPKEEKE 344
+ SP K K+
Sbjct: 1431 DSKSPGKGRKK 1441
Score = 48.1 bits (113), Expect = 2e-05
Identities = 68/322 (21%), Positives = 124/322 (38%), Gaps = 25/322 (7%)
Query: 53 STKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKS 112
S K E + P D K Q E + + G E +++ K K T+
Sbjct: 947 SKKGTEEKKKPSDFKKKVIKMEQQYESSSD--GTEKLPEREEICHFPKGIKQIKNGTTDG 1004
Query: 113 GSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEA 172
+++ +D TSK EL + + G + ED +++GA + +K G +
Sbjct: 1005 EKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGR-EKKRCKLLGKSS 1063
Query: 173 QTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKD---GSNKSGAEEQ 229
+ +D + +DG + S + + ++ + K+ K+ GS+ S AEE
Sbjct: 1064 RKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEES 1123
Query: 230 GPIDGPSKSGAEEQTSKDSPNKVVPE------QPSRKDHSKPISNPSDNKELPKADTNQL 283
D K +++TS +V E + S K I++ S + ++ D N +
Sbjct: 1124 SE-DNKKK---KQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITS-SSSSDIEDDDQNSI 1178
Query: 284 ----ADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPP 339
+D+ K+ P T +E S V+ +DDD PE
Sbjct: 1179 GEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD---DDDDNDPENRIAK 1235
Query: 340 KEEKEKMSGSASSENREGTLSD 361
K E++ + SS+ +G+ D
Sbjct: 1236 KMLLEEIKANLSSD-EDGSSDD 1256
Score = 42.4 bits (98), Expect = 8e-04
Identities = 74/382 (19%), Positives = 138/382 (36%), Gaps = 51/382 (13%)
Query: 23 TESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPN 82
TE +E G S + +R S ++ E Q S S SS ++ ED
Sbjct: 1074 TEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQ----SGSSSSDAEESSEDNKK 1129
Query: 83 KSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGA 142
K Q+ SS K K +K ++ ++ ++ + ++S S ++S G+ +
Sbjct: 1130 KK------QRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSS 1183
Query: 143 EAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNK--SGADGQTPKDGSSKSGAED 200
+ Q + P + SG EA +K VP D P++ +K +
Sbjct: 1184 DEQ--KIKPVTENLVLSSHTGFCQSSGDEA-LSKSVPVTVDDDDDDNDPENRIAKKMLLE 1240
Query: 201 QTPKDVPN-KSGAEKQTPKDGSNKSGAE-EQGPIDGPSKSGAEEQTSKDSPNKVVPEQPS 258
+ ++ + + G+ P++G ++G + E+ P D +K+ ++ DS P
Sbjct: 1241 EIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRH 1300
Query: 259 RKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLI-SPPQEEVKSSEP 317
R K + ++ E K + + + +E E++D S EEV SE
Sbjct: 1301 RLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESED 1360
Query: 318 T--------------------------------EDVEPKEAEDDDTGPEEGSPPKEEKEK 345
ED + + + EE +EE+E+
Sbjct: 1361 EQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEE 1420
Query: 346 MSGSASSENREGTLSDSTGSEK 367
EN + + S G +K
Sbjct: 1421 EEEEEEDEN-DDSKSPGKGRKK 1441
Score = 40.0 bits (92), Expect = 0.004
Identities = 83/373 (22%), Positives = 145/373 (38%), Gaps = 49/373 (13%)
Query: 43 HPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDT---------PNKSGAEAKT--- 90
H +L GS+ + + ++ + SSAE +DT P K A A T
Sbjct: 827 HKNLKTSQEGSSD---DAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGV 883
Query: 91 -QKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPED 149
+ +S + +K + +K S+ TK + K L + K +T ED
Sbjct: 884 DKLSGKEQSFTSLEVRKVAETKEKSKHLKTK-TCKKVQDGLSDIAEKFLKKDQSDETSED 942
Query: 150 SPNRS--GAEAKTQKDSPSKS--------GSEAQTTKDVPNKSGADGQTPKDGSSKSGAE 199
+S G E K + K S + T+ +P + K+G
Sbjct: 943 DKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTT 1002
Query: 200 D--QTPKDVPNKSGAEKQTPKDGSNKS---GAEEQGPIDGPSKSGAEEQTSKDSPNKVVP 254
D + K + +K+ +K D + KS G D SK+GA + K +
Sbjct: 1003 DGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCK---LL 1059
Query: 255 EQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQ-EEVK 313
+ SRK + S+ K K D +DK + E E +L S +E++
Sbjct: 1060 GKSSRK--RQDCSSSDTEKYSMKEDGCNSSDK-----RLKRIELRERRNLSSKRNTKEIQ 1112
Query: 314 SSEPTEDVEPKEAEDDDTGPEEGSPPKE-----EKEKMSGSASSENREGTLSDSTGSEKD 368
S + D E + +ED+ + S K+ EK++ S S++ ++ ++ S+ S+ +
Sbjct: 1113 SGSSSSDAE-ESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIE 1171
Query: 369 DLYPNGSGNGSAE 381
D N G GS++
Sbjct: 1172 DDDQNSIGEGSSD 1184
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 63.2 bits (152), Expect = 5e-10
Identities = 81/323 (25%), Positives = 135/323 (41%), Gaps = 51/323 (15%)
Query: 75 QTPEDTPNKSGAEAK-TQKDSSNKSGAEAKTQKGSTSKS---GSEAQTTKDSTSKSHPEL 130
+T D ++G + K +K S+ SG++ T+KG ++KS + + T+ +S EL
Sbjct: 762 KTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSEL 821
Query: 131 QTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNK---SGADGQ 187
+ S K GA T + PN ++ ++ + SK G + Q K++ S D +
Sbjct: 822 EKEIKSMSKIGAARTTKKRIPNTKDFDS-SEDEKHSKKGMDNQGHKNLKTSQEGSSDDAE 880
Query: 188 TPKDGSSKSGAEDQTPKD---------VPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKS 238
++ + S AE KD +P K A T DG +K +EQ +
Sbjct: 881 RKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASAST--DGVDKLSGKEQSFTSLEVRK 938
Query: 239 GAE-EQTSKDSPNKV----------VPEQPSRKDHSKPISNPSDNKELPKADTNQLADKG 287
AE ++ SK K + E+ +KD S S D+K+ K T +
Sbjct: 939 VAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETS--EDDKKQSKKGTEE----- 991
Query: 288 KLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMS 347
K P FK + +I Q+ SS+ TE + +E E PK K+ +
Sbjct: 992 KKKPSDFKKK------VIKMEQQYESSSDGTEKLPERE--------EICHFPKGIKQIKN 1037
Query: 348 GSASSENREGTLSDSTGSEKDDL 370
G+ E + + D T +KD+L
Sbjct: 1038 GTTDGEKKSKKIRDKTSKKKDEL 1060
Score = 52.0 bits (123), Expect = 1e-06
Identities = 75/311 (24%), Positives = 112/311 (36%), Gaps = 57/311 (18%)
Query: 64 KDSPSKSSAEAQTPEDTPNKSG-AEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQ----- 117
K + SS+ + +D N G + QK + G SG EA
Sbjct: 1196 KQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVP 1255
Query: 118 -TTKDSTSKSHPELQTPKD----------STGKSGAEAQTPEDSPNRSGA---------E 157
T D + PE + K S+ + G+ PE+ R+G E
Sbjct: 1256 VTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEE 1315
Query: 158 AKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQT- 216
AK Q +S S S SE ++ T DG +SG EK+T
Sbjct: 1316 AKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDG----------------ESGEEKKTK 1359
Query: 217 PKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSR-KDHSKPISNPSDNKEL 275
PK+ G + K +E+ D V E+ S +D +P + + EL
Sbjct: 1360 PKEHKEVKGRNRR-------KVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL 1412
Query: 276 PKADTNQLADKGKLSPHAFKTE--SGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGP 333
+ NQ + K K K + S E S +EE K E E+ E +E E++D
Sbjct: 1413 ---EENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEE-EEEDEND 1468
Query: 334 EEGSPPKEEKE 344
+ SP K K+
Sbjct: 1469 DSKSPGKGRKK 1479
Score = 48.1 bits (113), Expect = 2e-05
Identities = 68/322 (21%), Positives = 124/322 (38%), Gaps = 25/322 (7%)
Query: 53 STKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKS 112
S K E + P D K Q E + + G E +++ K K T+
Sbjct: 985 SKKGTEEKKKPSDFKKKVIKMEQQYESSSD--GTEKLPEREEICHFPKGIKQIKNGTTDG 1042
Query: 113 GSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEA 172
+++ +D TSK EL + + G + ED +++GA + +K G +
Sbjct: 1043 EKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGR-EKKRCKLLGKSS 1101
Query: 173 QTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKD---GSNKSGAEEQ 229
+ +D + +DG + S + + ++ + K+ K+ GS+ S AEE
Sbjct: 1102 RKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEES 1161
Query: 230 GPIDGPSKSGAEEQTSKDSPNKVVPE------QPSRKDHSKPISNPSDNKELPKADTNQL 283
D K +++TS +V E + S K I++ S + ++ D N +
Sbjct: 1162 SE-DNKKK---KQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITS-SSSSDIEDDDQNSI 1216
Query: 284 ----ADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPP 339
+D+ K+ P T +E S V+ +DDD PE
Sbjct: 1217 GEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD---DDDDNDPENRIAK 1273
Query: 340 KEEKEKMSGSASSENREGTLSD 361
K E++ + SS+ +G+ D
Sbjct: 1274 KMLLEEIKANLSSD-EDGSSDD 1294
Score = 42.4 bits (98), Expect = 8e-04
Identities = 74/382 (19%), Positives = 138/382 (36%), Gaps = 51/382 (13%)
Query: 23 TESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPN 82
TE +E G S + +R S ++ E Q S S SS ++ ED
Sbjct: 1112 TEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQ----SGSSSSDAEESSEDNKK 1167
Query: 83 KSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGA 142
K Q+ SS K K +K ++ ++ ++ + ++S S ++S G+ +
Sbjct: 1168 KK------QRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSS 1221
Query: 143 EAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNK--SGADGQTPKDGSSKSGAED 200
+ Q + P + SG EA +K VP D P++ +K +
Sbjct: 1222 DEQ--KIKPVTENLVLSSHTGFCQSSGDEA-LSKSVPVTVDDDDDDNDPENRIAKKMLLE 1278
Query: 201 QTPKDVPN-KSGAEKQTPKDGSNKSGAE-EQGPIDGPSKSGAEEQTSKDSPNKVVPEQPS 258
+ ++ + + G+ P++G ++G + E+ P D +K+ ++ DS P
Sbjct: 1279 EIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRH 1338
Query: 259 RKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLI-SPPQEEVKSSEP 317
R K + ++ E K + + + +E E++D S EEV SE
Sbjct: 1339 RLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESED 1398
Query: 318 T--------------------------------EDVEPKEAEDDDTGPEEGSPPKEEKEK 345
ED + + + EE +EE+E+
Sbjct: 1399 EQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEE 1458
Query: 346 MSGSASSENREGTLSDSTGSEK 367
EN + + S G +K
Sbjct: 1459 EEEEEEDEN-DDSKSPGKGRKK 1479
Score = 40.0 bits (92), Expect = 0.004
Identities = 83/373 (22%), Positives = 145/373 (38%), Gaps = 49/373 (13%)
Query: 43 HPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDT---------PNKSGAEAKT--- 90
H +L GS+ + + ++ + SSAE +DT P K A A T
Sbjct: 865 HKNLKTSQEGSSD---DAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGV 921
Query: 91 -QKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPED 149
+ +S + +K + +K S+ TK + K L + K +T ED
Sbjct: 922 DKLSGKEQSFTSLEVRKVAETKEKSKHLKTK-TCKKVQDGLSDIAEKFLKKDQSDETSED 980
Query: 150 SPNRS--GAEAKTQKDSPSKS--------GSEAQTTKDVPNKSGADGQTPKDGSSKSGAE 199
+S G E K + K S + T+ +P + K+G
Sbjct: 981 DKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTT 1040
Query: 200 D--QTPKDVPNKSGAEKQTPKDGSNKS---GAEEQGPIDGPSKSGAEEQTSKDSPNKVVP 254
D + K + +K+ +K D + KS G D SK+GA + K +
Sbjct: 1041 DGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCK---LL 1097
Query: 255 EQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQ-EEVK 313
+ SRK + S+ K K D +DK + E E +L S +E++
Sbjct: 1098 GKSSRK--RQDCSSSDTEKYSMKEDGCNSSDK-----RLKRIELRERRNLSSKRNTKEIQ 1150
Query: 314 SSEPTEDVEPKEAEDDDTGPEEGSPPKE-----EKEKMSGSASSENREGTLSDSTGSEKD 368
S + D E + +ED+ + S K+ EK++ S S++ ++ ++ S+ S+ +
Sbjct: 1151 SGSSSSDAE-ESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIE 1209
Query: 369 DLYPNGSGNGSAE 381
D N G GS++
Sbjct: 1210 DDDQNSIGEGSSD 1222
>gi|30795231 brain abundant, membrane attached signal protein 1
[Homo sapiens]
Length = 227
Score = 62.4 bits (150), Expect = 8e-10
Identities = 52/205 (25%), Positives = 88/205 (42%), Gaps = 13/205 (6%)
Query: 51 GGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQ--KGS 108
G +T+ P+ + + AEA+ ++ P++ AE K ++ K A AK + K
Sbjct: 28 GAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQD-AEGKAEEKEGEKDAAAAKEEAPKAE 86
Query: 109 TSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKS 168
K+ A+ + E P + G +A +P S A A ++ PSK
Sbjct: 87 PEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAGEE--PSKE 144
Query: 169 GSEAQTTKDVPNKSGADGQTPKDGS----SKSGAEDQTP--KDVPNKSGAEKQTPKDGSN 222
E + T + P A +T DG+ SK G+ + P K+ P + A TPK
Sbjct: 145 EGEPKKT-EAPAAPAAQ-ETKSDGAPASDSKPGSSEAAPSSKETPAATEAPSSTPKAQGP 202
Query: 223 KSGAEEQGPIDGPSKSGAEEQTSKD 247
+ AEE P++ P+ + + T K+
Sbjct: 203 AASAEEPKPVEAPAANSDQTVTVKE 227
Score = 48.1 bits (113), Expect = 2e-05
Identities = 49/233 (21%), Positives = 92/233 (39%), Gaps = 26/233 (11%)
Query: 48 QRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKG 107
++ G + + K + ++ E TP+++ ++ AE K+ K +A+ K
Sbjct: 8 KKKGYNVNDEKAKEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEG-KA 66
Query: 108 STSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSK 167
+ +A K+ K+ PE + G + A+A+ P+ A + Q
Sbjct: 67 EEKEGEKDAAAAKEEAPKAEPE-----KTEGAAEAKAEPPK-------APEQEQAAPGPA 114
Query: 168 SGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGS----NK 223
+G EA + + A+ P G S E + K + A ++T DG+ +K
Sbjct: 115 AGGEAPKAAEAA-AAPAESAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSK 173
Query: 224 SGAEEQGPI--DGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKE 274
G+ E P + P+ + A T K E+P KP+ P+ N +
Sbjct: 174 PGSSEAAPSSKETPAATEAPSSTPKAQGPAASAEEP------KPVEAPAANSD 220
Score = 47.0 bits (110), Expect = 3e-05
Identities = 47/202 (23%), Positives = 76/202 (37%), Gaps = 17/202 (8%)
Query: 19 PLLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPE 78
P A E + +E +P ++ G + + + PK P K+ A+
Sbjct: 42 PQAAAEPAEAKEGKEKPDQ---DAEGKAEEKEGEKDAAAAKEEAPKAEPEKTEGAAEAKA 98
Query: 79 DTPNKSGAEAKTQKDSSNKSGAEA-KTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDST 137
+ P A + Q +G EA K + + + + S A + SK E PK
Sbjct: 99 EPPK---APEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEEGE---PK--- 149
Query: 138 GKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSG 197
K+ A A GA A DS S A ++K+ P + A TPK +
Sbjct: 150 -KTEAPAAPAAQETKSDGAPA---SDSKPGSSEAAPSSKETPAATEAPSSTPKAQGPAAS 205
Query: 198 AEDQTPKDVPNKSGAEKQTPKD 219
AE+ P + P + + T K+
Sbjct: 206 AEEPKPVEAPAANSDQTVTVKE 227
Score = 45.1 bits (105), Expect = 1e-04
Identities = 42/182 (23%), Positives = 76/182 (41%), Gaps = 21/182 (11%)
Query: 190 KDGSSKSGA--EDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTS-K 246
KD ++ A E+ TPK+ ++ AE K+G K + +G + K G ++ + K
Sbjct: 22 KDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAE--EKEGEKDAAAAK 79
Query: 247 DSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLIS 306
+ K PE+ +K E PKA + A G + GE
Sbjct: 80 EEAPKAEPEKTEGAAEAKA--------EPPKAPEQEQAAPGPAA-------GGEAPKAAE 124
Query: 307 PPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSE 366
+S+ P EP + E + E + P ++ K G+ +S+++ G+ S++ S
Sbjct: 125 AAAAPAESAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGS-SEAAPSS 183
Query: 367 KD 368
K+
Sbjct: 184 KE 185
Score = 43.5 bits (101), Expect = 4e-04
Identities = 47/235 (20%), Positives = 89/235 (37%), Gaps = 17/235 (7%)
Query: 99 GAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEA 158
G +K +KG + K + + E TPK+S ++ AE AEA
Sbjct: 3 GKLSKKKKGYNVNDEKAKEKDKKAEGAATEEEGTPKESEPQAAAEP-----------AEA 51
Query: 159 KTQKDSPSKSG-SEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTP 217
K K+ P + +A+ + + + A + PK K+ + + P E+ P
Sbjct: 52 KEGKEKPDQDAEGKAEEKEGEKDAAAAKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAP 111
Query: 218 KDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPK 277
+ + P++S A + + P+K E + + P + + + P
Sbjct: 112 GPAAGGEAPKAAEAAAAPAESAA--PAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPA 169
Query: 278 ADTNQLADKGKLSPHAFKTESGEETDLISP-PQEEVKSSEPTEDVEPKEAEDDDT 331
+D+ + +P + +T + E +P Q S+E + VE A D T
Sbjct: 170 SDSK--PGSSEAAPSSKETPAATEAPSSTPKAQGPAASAEEPKPVEAPAANSDQT 222
Score = 35.0 bits (79), Expect = 0.13
Identities = 38/174 (21%), Positives = 66/174 (37%), Gaps = 29/174 (16%)
Query: 213 EKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDN 272
E+ TPK+ ++ AE AE + K+ P++ + K+ K + +
Sbjct: 33 EEGTPKESEPQAAAEP-----------AEAKEGKEKPDQDAEGKAEEKEGEKDAA--AAK 79
Query: 273 KELPKADTNQLADKGKLSPHAFKTESGEETDLISP--PQEEVKSSEPTEDVEPKEAEDDD 330
+E PKA+ KTE E P P++E + P E +A +
Sbjct: 80 EEAPKAEPE-------------KTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAA 126
Query: 331 TGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYP-NGSGNGSAESS 383
P E + P +E + E + + K D P + S GS+E++
Sbjct: 127 AAPAESAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSEAA 180
>gi|109637759 calpastatin isoform f [Homo sapiens]
Length = 750
Score = 62.4 bits (150), Expect = 8e-10
Identities = 77/346 (22%), Positives = 135/346 (39%), Gaps = 28/346 (8%)
Query: 34 RPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKD 93
R +A TH +S++ +++S +P K S K +A + + + +G A K
Sbjct: 15 RRAAAARRTHEHVSEK---TSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKV 71
Query: 94 SSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAE-----AQTPE 148
S++ + T + + K S S L TG + A +++ E
Sbjct: 72 SASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAE 131
Query: 149 DSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPN 208
P+ E KT+ +G E + +G + K G K + TP VP
Sbjct: 132 QQPSEKSTEPKTKPQDMISAGGE--------SVAGITAISGKPGDKKKEKKSLTPA-VPV 182
Query: 209 KSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDH--SKPI 266
+S +K + K G + + + + GP ++ EE T+ P P + + + +
Sbjct: 183 ESKPDKPSGKSGMDAALDDLIDTLGGPEET-EEENTTYTGPEVSDPMSSTYIEELGKREV 241
Query: 267 SNPSDNKEL---PKADTNQLADKGK-LSP-HAFKTESGEETDLISPPQEEVKSSEPTEDV 321
+ P +EL + T AD K + P A S + T P K +E E
Sbjct: 242 TIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT--CGSPTAAGKKTEKEEST 299
Query: 322 EPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEK 367
E +A+ T +PP+E+K K+ S+ LS S G+ +
Sbjct: 300 EVLKAQSAGT-VRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQ 344
Score = 52.0 bits (123), Expect = 1e-06
Identities = 76/334 (22%), Positives = 132/334 (39%), Gaps = 55/334 (16%)
Query: 33 VRPSAGNVSTHPSLSQRPGGSTKSHPEPQT----PKDSPSKSS-----------AEAQTP 77
V S+G S S++ + K+ PE ++ PK P ++S A +++
Sbjct: 71 VSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSA 130
Query: 78 EDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDST 137
E P++ E KT+ +G E+ + S + + K S + + P P +
Sbjct: 131 EQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPS 190
Query: 138 GKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSG 197
GKSG +A +D + G +T++++ + +G E D S +
Sbjct: 191 GKSGMDAAL-DDLIDTLGGPEETEEENTTYTGPEV-----------------SDPMSSTY 232
Query: 198 AEDQTPKDV--PNKSGAEKQTPKDGSNKSGAEEQGPIDGP--------------SKSGAE 241
E+ ++V P K E K+G A+ PI GP S + A
Sbjct: 233 IEELGKREVTIPPKY-RELLAKKEGITGPPADSSKPI-GPDDAIDALSSDFTCGSPTAAG 290
Query: 242 EQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEE 301
++T K+ +V+ Q + S + P + K + DT LS ++ E
Sbjct: 291 KKTEKEESTEVLKAQSAGTVRS--AAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPE 348
Query: 302 TDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEE 335
DL S +EV ++ E+ K EDD+T P E
Sbjct: 349 LDLRS--IKEVDEAKAKEEKLEKCGEDDETIPSE 380
Score = 33.9 bits (76), Expect = 0.30
Identities = 33/160 (20%), Positives = 55/160 (34%), Gaps = 18/160 (11%)
Query: 108 STSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSK 167
ST+++G+ + T S L DS G+ + E+ P + K + + K
Sbjct: 591 STTQAGAPPRDTSQSDKDLDDALDKLSDSLGQR--QPDPDENKPMEDKVKEKAKAEHRDK 648
Query: 168 SGSEAQTT--------------KDV--PNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSG 211
G T K V P K D + P D A P+ +
Sbjct: 649 LGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTE 708
Query: 212 AEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNK 251
+ T KD K+ + + P +G + + T + S K
Sbjct: 709 TSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPK 748
Score = 33.1 bits (74), Expect = 0.51
Identities = 41/189 (21%), Positives = 70/189 (37%), Gaps = 23/189 (12%)
Query: 107 GSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPS 166
G + S + + K + + S QTP +T +A P ++S + D S
Sbjct: 563 GPQNASSLKFEDAKLAAAISEVVSQTPASTT-----QAGAPPRDTSQSDKDLDDALDKLS 617
Query: 167 KSGSEAQTTKDV--PNKSGADGQTPKDGSSKSGAEDQTP----KDVPNKSGAEKQ----T 216
S + Q D P + + + K G D T + + + +G +K T
Sbjct: 618 DSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPT 677
Query: 217 PKDGSNKSGAEEQGPIDG--------PSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISN 268
K +K A++Q PID PS + + T+KD K + K+ K +
Sbjct: 678 KKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDS 737
Query: 269 PSDNKELPK 277
+E K
Sbjct: 738 AKTTEETSK 746
Score = 32.0 bits (71), Expect = 1.1
Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 1/77 (1%)
Query: 59 EPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQT 118
+P T K SK A+ Q P D + + ++S + + + S+SK+
Sbjct: 674 KPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGK 733
Query: 119 TKDSTSKSHPELQTPKD 135
KDS +K+ E PKD
Sbjct: 734 AKDS-AKTTEETSKPKD 749
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 62.4 bits (150), Expect = 8e-10
Identities = 51/243 (20%), Positives = 106/243 (43%), Gaps = 17/243 (6%)
Query: 135 DSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSG--SEAQTTKDVPNKSGADGQTPKDG 192
D + ++ + + E + G D+P SG + A+ TK K+ +G + G
Sbjct: 10 DCSAEAREKMEQKEGKLSEDGTTVSPAADNPEMSGGGAPAEETKGTAGKAINEGPPTESG 69
Query: 193 SS-KSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNK 251
K+ AED ++ ++ + + ++G +E + + G +E+T+ S
Sbjct: 70 KQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKEETTVGSQ-- 127
Query: 252 VVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEE 311
E RK+ +K S+ KE + ++ ++K K K ESG++ D + E
Sbjct: 128 ---EMTGRKEETK-----SEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPE 179
Query: 312 VKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLY 371
K++ ED K A ++TG + + +++ A +E+++ + D +E +
Sbjct: 180 PKATVEEEDA--KTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKE-- 235
Query: 372 PNG 374
P+G
Sbjct: 236 PDG 238
Score = 56.6 bits (135), Expect = 4e-08
Identities = 67/326 (20%), Positives = 129/326 (39%), Gaps = 34/326 (10%)
Query: 53 STKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSG--AEAKTQKDSSNKS-----GAEAKTQ 105
S ++ + + + S+ D P SG A A+ K ++ K+ E+ Q
Sbjct: 12 SAEAREKMEQKEGKLSEDGTTVSPAADNPEMSGGGAPAEETKGTAGKAINEGPPTESGKQ 71
Query: 106 KGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRS----GAEAKTQ 161
+ + ++ G A+ ++ ++++ +++ GK AEA+ ++ + G++ T
Sbjct: 72 EKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKEETTVGSQEMTG 131
Query: 162 KDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAE-DQTPKDVPN-KSGAEKQTPKD 219
+ +KS + K+ S K+ +SG + D +D P K+ E++ K
Sbjct: 132 RKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPEPKATVEEEDAKT 191
Query: 220 GSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKAD 279
S + + + P + +E+ +S VV +D +K D KE K
Sbjct: 192 ASQEETGQRKECSTEPKEKATDEEAKAESQKAVV------EDEAKAEPKEPDGKEEAKHG 245
Query: 280 TNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPP 339
+ AD + + E EE + SP S E +DVE + P S P
Sbjct: 246 AKEEADAKE------EAEDAEEAEPGSP------SEEQEQDVEKEPEGGAGVIP---SSP 290
Query: 340 KEEKEKMSGSASSENREGTLSDSTGS 365
+E E +G + + +G D S
Sbjct: 291 EEWPESPTGEGHNLSTDGLGPDCVAS 316
Score = 46.6 bits (109), Expect = 4e-05
Identities = 50/232 (21%), Positives = 93/232 (40%), Gaps = 53/232 (22%)
Query: 21 LATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQ-TPKDSPSKSSAEAQT--- 76
LA+E K EE +P +G Q+ + + PEP+ T ++ +K++++ +T
Sbjct: 150 LASEKQKAEEKEAKPESG---------QKADANDRDKPEPKATVEEEDAKTASQEETGQR 200
Query: 77 ------PEDTPNKSGAEAKTQKDS-SNKSGAEAKTQKGST-----SKSGSEAQTTKDSTS 124
P++ A+A++QK +++ AE K G +K ++A+ +
Sbjct: 201 KECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEEAEDAE 260
Query: 125 KSHP-------ELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKD 177
++ P E K+ G +G +PE+ P +SP+ G T
Sbjct: 261 EAEPGSPSEEQEQDVEKEPEGGAGVIPSSPEEWP-----------ESPTGEGHNLST--- 306
Query: 178 VPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQ 229
G G + A + +P DVP + ++P G K A E+
Sbjct: 307 ----DGLGPDCVASGQTSPSASESSPSDVPQ---SPPESPSSGEKKEKAPER 351
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 62.0 bits (149), Expect = 1e-09
Identities = 85/402 (21%), Positives = 140/402 (34%), Gaps = 55/402 (13%)
Query: 19 PLLATESVKQEEAGVRPSAGNVSTH-----PSLSQRPGGSTKSHPEPQTPKDSP---SKS 70
PLL T + +E+ R GN +++ P L +PG +++ KD P K+
Sbjct: 956 PLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKA 1015
Query: 71 SAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQK----GSTSKSGSEAQTTKDSTSKS 126
E ++P + + T S G+ ++Q + Q K +
Sbjct: 1016 DTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVG 1075
Query: 127 HPELQTPKDSTG---KSGAEAQTPEDSPNRSGAEAK-TQKDSPSKSGSEAQTTKDVPNKS 182
P + S+G SG+++ S + S A K S S+ S ++ + + +
Sbjct: 1076 KPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQ 1135
Query: 183 GADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQG------------ 230
G+ G + SS+SG + P S K GS+ + + QG
Sbjct: 1136 GSSGSSQSKNSSQSGGK-------PGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSK 1188
Query: 231 PIDGPSKSGAEEQTSK-DSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKL 289
P PS S + K SP K VP P PIS+ S + G
Sbjct: 1189 PNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHM----------SGTS 1238
Query: 290 SPHAFKTESG----EETDLISPPQEE---VKSSEPTEDVEPKEAEDDDTGPEEGSPPKEE 342
S K+ SG +PP SS + + + G +G P
Sbjct: 1239 SSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRN 1298
Query: 343 KEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAESSH 384
K+ + + + G ++ G E D G + SSH
Sbjct: 1299 KKPSLTAVIDKLKHGVVTSGPGGE--DPLDGQMGVSTNSSSH 1338
Score = 55.8 bits (133), Expect = 7e-08
Identities = 81/357 (22%), Positives = 136/357 (38%), Gaps = 54/357 (15%)
Query: 33 VRPSAGNVSTHPSLSQRPGGSTK----SHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEA 88
+ PS + PS S+ PGGS K P P TP S +KS P SG+
Sbjct: 1182 MNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKS----------PISSGSGG 1231
Query: 89 KTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPE 148
+S+ SG ++ + GS SGS +Q T S++ S SG+ + +
Sbjct: 1232 SHMSGTSSSSGMKSSSGLGS---SGSLSQKTPPSSN----SCTASSSSFSSSGSSMSSSQ 1284
Query: 149 DSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDG----SSKSGAEDQTPK 204
+ S ++ ++ PS + + V SG G+ P DG S+ S + + K
Sbjct: 1285 NQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVT-SGPGGEDPLDGQMGVSTNSSSHPMSSK 1343
Query: 205 DVPNKSGAEKQTPKDGSNKSGAE---EQGPIDGPSKSGAEEQTSKDSPNKVV-------- 253
N SG E Q ++ S+K ++ +D K+ + K++
Sbjct: 1344 H--NMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGS 1401
Query: 254 PEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISP---PQE 310
P ++ KP + + P+ +++ +S K E G + SP PQ
Sbjct: 1402 PSIKAKVTLQKPGESSGEGLR-PQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQN 1460
Query: 311 EVKSSEPTEDVEPKE-----AEDDDTGP------EEGSPPKEEKEKMSGSASSENRE 356
SE + K + DD P E+ K+EK+K+ +R+
Sbjct: 1461 LDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRD 1517
Score = 47.4 bits (111), Expect = 3e-05
Identities = 66/306 (21%), Positives = 117/306 (38%), Gaps = 31/306 (10%)
Query: 36 SAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKS--SAEAQTPEDTPNKSGAEAKTQKD 93
S+G+VS+ S S S+ S + K SKS S+ ++ + G+ +Q
Sbjct: 1085 SSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSK 1144
Query: 94 SSNKSGAEAK----TQKG-STSKSGSEAQTTKDSTSKSHPELQTPKDSTGKS---GAEAQ 145
+S++SG + T+ G S+ S ++ + +S +P L P S S G +
Sbjct: 1145 NSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDK 1204
Query: 146 TPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQ-TPK 204
G ++ SP SGS + S + G G SG+ Q TP
Sbjct: 1205 LASPMKPVPGTPPSSKAKSPISSGSGG---SHMSGTSSSSGMKSSSGLGSSGSLSQKTPP 1261
Query: 205 DVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSK 264
+ + + GS+ S ++ Q G SK + + K S V+ + H
Sbjct: 1262 SSNSCTASSSSFSSSGSSMSSSQNQ---HGSSKGKSPSRNKKPSLTAVI----DKLKHGV 1314
Query: 265 PISNPSDNKEL-------PKADTNQLADKGKLSPHAF---KTESGEETDLISPPQEEVKS 314
S P L + ++ ++ K +S F + +S ++ +S V S
Sbjct: 1315 VTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDS 1374
Query: 315 SEPTED 320
S+ T +
Sbjct: 1375 SKKTSE 1380
Score = 46.6 bits (109), Expect = 4e-05
Identities = 67/265 (25%), Positives = 108/265 (40%), Gaps = 25/265 (9%)
Query: 46 LSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQ 105
L + G ST S P + K + S + + + +KS S+K +E+K
Sbjct: 1325 LDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNV 1384
Query: 106 KGST--SKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPED----SPNRSGAEAK 159
GST +K + K+ LQ P +S+G+ G Q SP SG+ K
Sbjct: 1385 -GSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGE-GLRPQMASSKNYGSPLISGSTPK 1442
Query: 160 TQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKD 219
++ SPS S S A T +++ ++S + + S + D + +P E T K
Sbjct: 1443 HERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLP-----EYSTEKH 1497
Query: 220 GSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKAD 279
+K E++ D ++ K + + PE S+ PIS SD ++
Sbjct: 1498 KKHKK--EKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSK----SPIS--SDQSLSMTSN 1549
Query: 280 TNQLADK-GKLSPHAFKTESGEETD 303
T AD+ +LSP GEE D
Sbjct: 1550 TILSADRPSRLSPDFM---IGEEDD 1571
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 62.0 bits (149), Expect = 1e-09
Identities = 80/362 (22%), Positives = 127/362 (35%), Gaps = 44/362 (12%)
Query: 68 SKSSAEAQTPEDTPNKSGAEAKTQKDSS-NKSGAEAKTQKGS--TSKSGSEAQTTKDSTS 124
S ++ A E + SGA T DSS SGA T S TS S A ++ ST+
Sbjct: 114 SSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTT 173
Query: 125 KSHPELQTPKDSTGKS--GAEAQTPEDSPNRSGAEAKTQKDSPSKS-------GSEAQTT 175
S T +S+ S + A E S SGA T +S + S SE+ TT
Sbjct: 174 SSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTT 233
Query: 176 KD-VPNKSGADGQTPKDG----------SSKSGAEDQTPKD-------VPNKSGAEKQTP 217
+ ++ TP G ++ SGA T + + + +E TP
Sbjct: 234 SSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTP 293
Query: 218 KDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPK 277
G+N + E + SGA T+ DS + S S+ + +
Sbjct: 294 SSGANTATNSE----SSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSE 349
Query: 278 ADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGS 337
+ T + + T SG T + V S T +E T +
Sbjct: 350 SSTTSSGASTATNSGSSTTSSGTST-ATNSESSTVSSGASTATT----SESSTTSSGAST 404
Query: 338 PPKEEKEKMSGSASSENREGTLSDSTGSEK-----DDLYPNGSGNGSAESSHFFAYLVTA 392
E +S AS+ + + S+G+ + GSG + H ++ +
Sbjct: 405 ATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSAST 464
Query: 393 AI 394
A+
Sbjct: 465 AV 466
Score = 61.2 bits (147), Expect = 2e-09
Identities = 68/248 (27%), Positives = 90/248 (36%), Gaps = 28/248 (11%)
Query: 22 ATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTP 81
A+ + E AG + S + G ST ++ E TP S + A E +
Sbjct: 207 ASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTP----SSGAGTATNSESST 262
Query: 82 NKSGAEAKTQKDSSN----------------KSGAEAKT-QKGSTSKSGSEAQTTKDS-- 122
SGA T +SS SGA T + ST+ SG+ T DS
Sbjct: 263 TSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSST 322
Query: 123 TSKSHPELQTPKDSTGKSGAEAQT-PEDSPNRSGAEAKTQKDSPSKSG--SEAQTTKDVP 179
TS + ST SGA T E S SGA T S + S S A ++
Sbjct: 323 TSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESST 382
Query: 180 NKSGADGQTPKDGS-SKSGAEDQTPKDVPN-KSGAEKQTPKDGSNKSGAEEQGPIDGPSK 237
SGA T + S + SGA T + SGA T + S S G S
Sbjct: 383 VSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSV 442
Query: 238 SGAEEQTS 245
+ A T+
Sbjct: 443 TSAGSGTA 450
Score = 46.2 bits (108), Expect = 6e-05
Identities = 74/329 (22%), Positives = 110/329 (33%), Gaps = 30/329 (9%)
Query: 70 SSAEAQTPEDTPNK---SGAEAKTQKDSS-NKSGAEAKTQKGSTSKSGSEAQTTKD---S 122
+S E T +T + SGA T SS SG T GS+ S + T +
Sbjct: 23 NSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHT 82
Query: 123 TSKSHPELQTPKDSTGKSGAEAQT-PEDSPNRSGAEAKTQKDS--PSKSGSEAQTTKDVP 179
TS + ST SG T E S SGA T +S PS S A +
Sbjct: 83 TSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSST 142
Query: 180 NKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSG 239
SGA T D S+ T + + +E T G++ + E + S
Sbjct: 143 TSSGASTATNSDSST-------TSSEASTATNSESSTTSSGASTATNSESSTV----SSR 191
Query: 240 AEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESG 299
A T+ +S + S+ SN + ++ T + + SG
Sbjct: 192 ASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSG 251
Query: 300 EETDLISPPQEEVKSSEPTEDVEPKEAEDDDTG-----PEEGSPPKEEKEKMSGSASSEN 354
T + E +S E+ +G E S P + S SS
Sbjct: 252 AGT---ATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTT 308
Query: 355 REGTLSDSTGSEKDDLYPNGSGNGSAESS 383
G + +T S+ S ++ESS
Sbjct: 309 SSGA-NTATNSDSSTTSSGASTATNSESS 336
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 61.6 bits (148), Expect = 1e-09
Identities = 69/322 (21%), Positives = 124/322 (38%), Gaps = 57/322 (17%)
Query: 45 SLSQRPGGSTKSHPEPQTPKDSPSKSSAE---AQTPEDTPN-KSGAEAKTQKDSSNKSGA 100
SL P + S P+ PK + + E T ED+ N KS +A+ ++D + +S +
Sbjct: 2500 SLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESES 2559
Query: 101 EAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKT 160
+ + GS+S S S + S S++ E + K+ G G + + +R+ + A +
Sbjct: 2560 SSSSSSGSSSSSSSSSS----SGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASS 2615
Query: 161 QKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDG 220
S S S S + ++ + S + + SS S + + + S + + D
Sbjct: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDE 2675
Query: 221 SNKSGAEEQG---PIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPK 277
+ ++++ P GPS A LP
Sbjct: 2676 DSSCSSDDEAAPAPTAGPSAQAA----------------------------------LPT 2701
Query: 278 ADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGS 337
T Q A K + S H+ G++T PQ + +PT+ ++PK + P++
Sbjct: 2702 KATKQ-AGKARPSAHS----PGKKT---PAPQPQAPPPQPTQPLQPKAQAGAKSRPKKRE 2753
Query: 338 ----PPKEEKEKMSGSASSENR 355
P +E K S ENR
Sbjct: 2754 GVHLPTTKELAKRQRLPSVENR 2775
Score = 56.2 bits (134), Expect = 6e-08
Identities = 54/262 (20%), Positives = 101/262 (38%), Gaps = 25/262 (9%)
Query: 41 STHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGA 100
+T L+Q PG + + PK SP K+ AE E++ E+ + S + S +
Sbjct: 2520 ATDGDLAQEPGPGL-TFEDSGNPK-SPDKAQAEQDGAEES------ESSSSSSSGSSSSS 2571
Query: 101 EAKTQKGSTSKSGSEAQTTKD-------------STSKSHPELQTPKDSTGKSGAEAQTP 147
+ + GS ++ E D S+ + P + S+ S + + +
Sbjct: 2572 SSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSS 2631
Query: 148 EDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVP 207
S + S + + + S S S S + ++ + S + T + SS S ++ P
Sbjct: 2632 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTA 2691
Query: 208 NKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPIS 267
S A+ P + ++G + + P K Q P P QP + +K S
Sbjct: 2692 GPS-AQAALPTKATKQAG-KARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAK--S 2747
Query: 268 NPSDNKELPKADTNQLADKGKL 289
P + + T +LA + +L
Sbjct: 2748 RPKKREGVHLPTTKELAKRQRL 2769
Score = 41.2 bits (95), Expect = 0.002
Identities = 71/383 (18%), Positives = 129/383 (33%), Gaps = 52/383 (13%)
Query: 47 SQRPGGSTKSHPEPQTPKDSPSKSSA--EAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKT 104
S+ PG + + K +++ E ++ P+ A + S KS E
Sbjct: 2322 SEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVD 2381
Query: 105 QKGSTSKSG------SEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQT---PEDSPNRSG 155
++ K+ S A S P + P +T + A T P ++
Sbjct: 2382 KRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKAR 2441
Query: 156 AEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAED------QTPKDV--- 206
A ++ P + G EA+ + ++ ++ K + ED Q PK +
Sbjct: 2442 AAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSL 2501
Query: 207 ---PNKSGAE-------KQTPKDGSNKSGA----EEQGPIDGPSKSGAEEQTSKDSPNKV 252
P +G+ K T D + + G E+ G P K+ AE+ +++S +
Sbjct: 2502 GSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSS 2561
Query: 253 VPEQPSRKDHSKPISNPSDNKELPKADTN------------QLADKGKLSPHAFKTESGE 300
S S S+ S+ + + D N A SP + + S
Sbjct: 2562 SSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSS 2621
Query: 301 ETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLS 360
+ S SS + + + S S S+SS + T
Sbjct: 2622 SSSSSS------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDE 2675
Query: 361 DSTGSEKDDLYPNGSGNGSAESS 383
DS+ S D+ P + SA+++
Sbjct: 2676 DSSCSSDDEAAPAPTAGPSAQAA 2698
Score = 40.8 bits (94), Expect = 0.002
Identities = 34/153 (22%), Positives = 68/153 (44%), Gaps = 12/153 (7%)
Query: 36 SAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSS 95
S+ + S+ S S S+ S + S S SS+ + + + + S + + T +DSS
Sbjct: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSS 2678
Query: 96 NKSGAEAKTQK--GSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPN- 152
S EA G ++++ + TK + K+ P +P T +A P+ +
Sbjct: 2679 CSSDDEAAPAPTAGPSAQAALPTKATKQA-GKARPSAHSPGKKTPAPQPQAPPPQPTQPL 2737
Query: 153 ----RSGAEAKTQKDSPSKSGSEAQTTKDVPNK 181
++GA+++ +K + G TTK++ +
Sbjct: 2738 QPKAQAGAKSRPKK----REGVHLPTTKELAKR 2766
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 61.6 bits (148), Expect = 1e-09
Identities = 87/385 (22%), Positives = 151/385 (39%), Gaps = 49/385 (12%)
Query: 18 VPLLATESVKQEEAGV-RPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQT 76
+P + T KQEE+ + + A + L + K PE + + K E +
Sbjct: 1185 IPPMVTTDQKQEESKLEKDKASALQEKKPLPEEK----KLIPEEEKIRSEEKKPLLEEKK 1240
Query: 77 PEDTPNKSGAEAKT-----QKDSSNKSGAEAKTQK------GSTSKSGSEAQTTKDSTSK 125
P K EAKT QK KS + +K T + G + QT +
Sbjct: 1241 PTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPS 1300
Query: 126 SHPE-LQTPKDSTGKSGAEAQTPEDSPNRSGAEA---KTQKDSPSKSGSEAQTTKDVPNK 181
P+ L D T K+ E P + E KT+K+ S +Q K
Sbjct: 1301 GTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGL 1360
Query: 182 SGADGQTPKDGSSKSGAEDQTPKDVPNKS-----GAEKQTPKDGSNKSGAEEQGPIDGPS 236
S D DG S S E P +P G +K + S+ S + ++
Sbjct: 1361 S--DTGYSSDGISSSLGE--IPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTV 1416
Query: 237 KSGAEEQTS---------KDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKG 287
S E Q S K P++V PEQP ++ ++ +S + E+ ++ ++ +
Sbjct: 1417 LSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLS---ETLEITISE-EEIKESQ 1472
Query: 288 KLSPHAFKTESGEETDLISPPQEEVKSSEPTEDV----EPKEAEDDDTGPEEGSPPKEEK 343
+ FK +S ++ I ++ + SE +D+ EP ++ ++ + E P+ ++
Sbjct: 1473 EERKDTFKKDSQQD---IPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKR 1529
Query: 344 EKMSGSASSENREGTLSDSTGSEKD 368
GS+SS+ + S +G E+D
Sbjct: 1530 RTSVGSSSSDEYKQEDSQGSGEEED 1554
Score = 55.5 bits (132), Expect = 1e-07
Identities = 63/266 (23%), Positives = 105/266 (39%), Gaps = 38/266 (14%)
Query: 27 KQEEAGVRPSAGNVSTHPSLSQRPG---------GSTKSHPEPQTPKDSPSKSSAEAQTP 77
K + +P A L+Q+PG G+TK +P P P++ + +
Sbjct: 323 KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPS 382
Query: 78 EDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDST 137
+ P G +A Q K+ A+ Q G + T K + P LQ+P +
Sbjct: 383 SEQP---GPKALAQPPGVGKTPAQ---QPGPAKPPTQQVGTPKPLAQQ--PGLQSPAKAP 434
Query: 138 GKSGAEAQTPEDS--PNRSGAEAKT--QKDSPSKSGSEAQ-TTKDVPNKSGADGQTPKD- 191
G + Q P P + KT Q+ P+K S+ K P + G P+
Sbjct: 435 GPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQP 494
Query: 192 GSSKSGAEDQ-TPKDVPNKSGAEKQTPKD-GSNKSGAEEQGPIDGPSKSGAEEQTSKDSP 249
GS+K ++ + K P + G K +P+ GS K +++ G ++K S
Sbjct: 495 GSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG-------------SAKPSA 541
Query: 250 NKVVPEQPSRKDHSKPISNPSDNKEL 275
+ P +PS + +KP+S K L
Sbjct: 542 QQPSPAKPSAQQSTKPVSQTGSGKPL 567
Score = 51.2 bits (121), Expect = 2e-06
Identities = 74/342 (21%), Positives = 117/342 (34%), Gaps = 41/342 (11%)
Query: 56 SHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSE 115
S +P+ K P + Q P TP A+ Q+D+S +A +G + K
Sbjct: 240 SSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVK---- 295
Query: 116 AQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTT 175
S S P +Q P TP P + K+Q + T
Sbjct: 296 ----PSLPSPSKPPIQQP------------TPGKPPAQQPGHEKSQPGPAKPPAQPSGLT 339
Query: 176 KDVPNKSG-ADGQTPKDGSSKSGAEDQTPKDVP-NKSGAEKQTPKDGSNKSGAEEQGPID 233
K + + G G++K A+ P P ++G+EK + + K+ A+ G
Sbjct: 340 KPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGK 399
Query: 234 GPSK--SGAEEQTSKDSPNKVVPEQPSRKDHSK-------PISNPSDNKELPKADTNQLA 284
P++ A+ T + K + +QP + +K P+ P K +P Q A
Sbjct: 400 TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK-IPA----QQA 454
Query: 285 DKGKLSPH---AFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKE 341
GK S K S PPQ+ + P + +P A+ P PP +
Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQ--QPGSAKPPSQQPGSTKPPPQ 512
Query: 342 EKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAESS 383
+ S S GS K SA+ S
Sbjct: 513 QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQS 554
Score = 46.2 bits (108), Expect = 6e-05
Identities = 78/365 (21%), Positives = 122/365 (33%), Gaps = 58/365 (15%)
Query: 28 QEEAGVRPSAGNVSTHPSLSQRPG--------GSTKSHPEPQTP------KDSPSKSSAE 73
Q+ +P V T L+Q+PG G TK+ + P + P K+SA+
Sbjct: 403 QQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462
Query: 74 AQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTP 133
P P++ AK + + Q GS + +TK + P +P
Sbjct: 463 QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQ-QPGSAKPPSQQPGSTKPPPQQPGPAKPSP 521
Query: 134 KDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPK-DG 192
+ G + +Q P A+ Q+ SP+K ++ T SG Q P
Sbjct: 522 QQP-GSTKPPSQQP------GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSP 574
Query: 193 SSKSGAEDQTPKDV---PNKSGAEKQTPKDGSNKSGAEEQGPI-------DGPSKSGAEE 242
S+K PK + N + P+ + + E Q + P + +E
Sbjct: 575 SAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKE 634
Query: 243 QTSKDSPNK--------VVPEQPSRKDHSKPI--------SNPSDNKELPKADTNQLADK 286
+ K VP P K + P+ S+P + PK D D
Sbjct: 635 WLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDL 694
Query: 287 GKLSPHAFK--------TESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSP 338
K +P K T G + P E S+P EP + D P
Sbjct: 695 SK-APEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDK 753
Query: 339 PKEEK 343
PK+ K
Sbjct: 754 PKQPK 758
Score = 41.2 bits (95), Expect = 0.002
Identities = 83/373 (22%), Positives = 133/373 (35%), Gaps = 53/373 (14%)
Query: 25 SVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKS 84
S+ + + + +AG H PG K P P P S + Q P
Sbjct: 937 SIFSQASNLISTAGQPGPHSQSG--PGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSI 994
Query: 85 GAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEA 144
+ +T+ ++ K E K ++ T K + T K P ++ K T + +A
Sbjct: 995 PVKKETKAPAAEK--LEPKAEQAPTVK--------RTETEKKPPPIKDSKSLTAEP-QKA 1043
Query: 145 QTP-----EDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNK-SGADGQTPKDGSSKSG- 197
P P + KT+ + SK T + N+ G P ++
Sbjct: 1044 VLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQE 1103
Query: 198 ---AEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGA----------EEQT 244
QT + + + G ++ P S + P + S+ A +EQ
Sbjct: 1104 WLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQE 1163
Query: 245 SKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKL-----SPHAFKTESG 299
K KV+ E K S K P T+Q ++ KL S K
Sbjct: 1164 VKTEAEKVILE--------KVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLP 1215
Query: 300 EETDLISPPQEEVKSSEPTEDVEPKE--AEDDDTGPE-EGSPPKEEKE---KMSGSASSE 353
EE LI P +E+++S E +E K+ ED PE + S P+E+K K + E
Sbjct: 1216 EEKKLI-PEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEE 1274
Query: 354 NREGTLSDSTGSE 366
EG ++ T E
Sbjct: 1275 KLEGRVAPKTVQE 1287
Score = 37.4 bits (85), Expect = 0.027
Identities = 52/226 (23%), Positives = 82/226 (36%), Gaps = 21/226 (9%)
Query: 118 TTKDSTSKS--HPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTT 175
TT + SKS P+ +PK ++ PE P + K P+ GS +
Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPE--PKKPPPLVK----QPTLHGSPSAKA 720
Query: 176 KDVPNKSGADGQTPKDGSSKSGAEDQTP--KDVPNKSGAEKQTPKDGSNKSGAEEQGPID 233
K P P S +D+ P D P + K T S+ S +
Sbjct: 721 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780
Query: 234 GPSKSGAEEQTSKDSPNKVVPEQPSRK-DHSKPISNPSDNKELPKADTNQLADKGKLSPH 292
+S AEE+T+ P K +PS+ + +P D+K +P+ A K+ H
Sbjct: 781 SKVQSQAEEKTT--PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRP-----ASDSKIISH 833
Query: 293 AFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSP 338
+ + + P Q K EP + + D +GSP
Sbjct: 834 PGPSSESKGQKQVDPVQ---KKEEPKKAQTKMSPKPDAKPMPKGSP 876
Score = 35.0 bits (79), Expect = 0.13
Identities = 52/249 (20%), Positives = 101/249 (40%), Gaps = 40/249 (16%)
Query: 39 NVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKS 98
+++ P R GS+ H TP SP+ S+ + + +P+ E+K Q+ + ++
Sbjct: 1703 SLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHR- 1761
Query: 99 GAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEA 158
G T +DS+ + EL+ ++ + E Q + R +
Sbjct: 1762 ------------PHGPLLPTIEDSSEEE--ELREEEELLKEQ--EKQREIEQQQRKSSSK 1805
Query: 159 KTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPK 218
K++KD K AQ ++ P +TP S+ S ED +P + ++ ++
Sbjct: 1806 KSKKD---KDELRAQRRRERP-------KTPP--SNLSPIEDASPTEELRQAAEMEEL-- 1851
Query: 219 DGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRK-DHSKPISNPSDNKELPK 277
++S E P G E SP K++ Q K + + +P+D + + +
Sbjct: 1852 ---HRSSCSEYSPSIESDPEGFE-----ISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQ 1903
Query: 278 ADTNQLADK 286
+ +Q A K
Sbjct: 1904 KEGSQKALK 1912
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 61.6 bits (148), Expect = 1e-09
Identities = 87/385 (22%), Positives = 151/385 (39%), Gaps = 49/385 (12%)
Query: 18 VPLLATESVKQEEAGV-RPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQT 76
+P + T KQEE+ + + A + L + K PE + + K E +
Sbjct: 1185 IPPMVTTDQKQEESKLEKDKASALQEKKPLPEEK----KLIPEEEKIRSEEKKPLLEEKK 1240
Query: 77 PEDTPNKSGAEAKT-----QKDSSNKSGAEAKTQK------GSTSKSGSEAQTTKDSTSK 125
P K EAKT QK KS + +K T + G + QT +
Sbjct: 1241 PTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPS 1300
Query: 126 SHPE-LQTPKDSTGKSGAEAQTPEDSPNRSGAEA---KTQKDSPSKSGSEAQTTKDVPNK 181
P+ L D T K+ E P + E KT+K+ S +Q K
Sbjct: 1301 GTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGL 1360
Query: 182 SGADGQTPKDGSSKSGAEDQTPKDVPNKS-----GAEKQTPKDGSNKSGAEEQGPIDGPS 236
S D DG S S E P +P G +K + S+ S + ++
Sbjct: 1361 S--DTGYSSDGISSSLGE--IPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTV 1416
Query: 237 KSGAEEQTS---------KDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKG 287
S E Q S K P++V PEQP ++ ++ +S + E+ ++ ++ +
Sbjct: 1417 LSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLS---ETLEITISE-EEIKESQ 1472
Query: 288 KLSPHAFKTESGEETDLISPPQEEVKSSEPTEDV----EPKEAEDDDTGPEEGSPPKEEK 343
+ FK +S ++ I ++ + SE +D+ EP ++ ++ + E P+ ++
Sbjct: 1473 EERKDTFKKDSQQD---IPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKR 1529
Query: 344 EKMSGSASSENREGTLSDSTGSEKD 368
GS+SS+ + S +G E+D
Sbjct: 1530 RTSVGSSSSDEYKQEDSQGSGEEED 1554
Score = 55.5 bits (132), Expect = 1e-07
Identities = 63/266 (23%), Positives = 105/266 (39%), Gaps = 38/266 (14%)
Query: 27 KQEEAGVRPSAGNVSTHPSLSQRPG---------GSTKSHPEPQTPKDSPSKSSAEAQTP 77
K + +P A L+Q+PG G+TK +P P P++ + +
Sbjct: 323 KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPS 382
Query: 78 EDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDST 137
+ P G +A Q K+ A+ Q G + T K + P LQ+P +
Sbjct: 383 SEQP---GPKALAQPPGVGKTPAQ---QPGPAKPPTQQVGTPKPLAQQ--PGLQSPAKAP 434
Query: 138 GKSGAEAQTPEDS--PNRSGAEAKT--QKDSPSKSGSEAQ-TTKDVPNKSGADGQTPKD- 191
G + Q P P + KT Q+ P+K S+ K P + G P+
Sbjct: 435 GPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQP 494
Query: 192 GSSKSGAEDQ-TPKDVPNKSGAEKQTPKD-GSNKSGAEEQGPIDGPSKSGAEEQTSKDSP 249
GS+K ++ + K P + G K +P+ GS K +++ G ++K S
Sbjct: 495 GSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG-------------SAKPSA 541
Query: 250 NKVVPEQPSRKDHSKPISNPSDNKEL 275
+ P +PS + +KP+S K L
Sbjct: 542 QQPSPAKPSAQQSTKPVSQTGSGKPL 567
Score = 51.2 bits (121), Expect = 2e-06
Identities = 74/342 (21%), Positives = 117/342 (34%), Gaps = 41/342 (11%)
Query: 56 SHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSE 115
S +P+ K P + Q P TP A+ Q+D+S +A +G + K
Sbjct: 240 SSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVK---- 295
Query: 116 AQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTT 175
S S P +Q P TP P + K+Q + T
Sbjct: 296 ----PSLPSPSKPPIQQP------------TPGKPPAQQPGHEKSQPGPAKPPAQPSGLT 339
Query: 176 KDVPNKSG-ADGQTPKDGSSKSGAEDQTPKDVP-NKSGAEKQTPKDGSNKSGAEEQGPID 233
K + + G G++K A+ P P ++G+EK + + K+ A+ G
Sbjct: 340 KPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGK 399
Query: 234 GPSK--SGAEEQTSKDSPNKVVPEQPSRKDHSK-------PISNPSDNKELPKADTNQLA 284
P++ A+ T + K + +QP + +K P+ P K +P Q A
Sbjct: 400 TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK-IPA----QQA 454
Query: 285 DKGKLSPH---AFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKE 341
GK S K S PPQ+ + P + +P A+ P PP +
Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQ--QPGSAKPPSQQPGSTKPPPQ 512
Query: 342 EKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAESS 383
+ S S GS K SA+ S
Sbjct: 513 QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQS 554
Score = 46.2 bits (108), Expect = 6e-05
Identities = 78/365 (21%), Positives = 122/365 (33%), Gaps = 58/365 (15%)
Query: 28 QEEAGVRPSAGNVSTHPSLSQRPG--------GSTKSHPEPQTP------KDSPSKSSAE 73
Q+ +P V T L+Q+PG G TK+ + P + P K+SA+
Sbjct: 403 QQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462
Query: 74 AQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTP 133
P P++ AK + + Q GS + +TK + P +P
Sbjct: 463 QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQ-QPGSAKPPSQQPGSTKPPPQQPGPAKPSP 521
Query: 134 KDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPK-DG 192
+ G + +Q P A+ Q+ SP+K ++ T SG Q P
Sbjct: 522 QQP-GSTKPPSQQP------GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSP 574
Query: 193 SSKSGAEDQTPKDV---PNKSGAEKQTPKDGSNKSGAEEQGPI-------DGPSKSGAEE 242
S+K PK + N + P+ + + E Q + P + +E
Sbjct: 575 SAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKE 634
Query: 243 QTSKDSPNK--------VVPEQPSRKDHSKPI--------SNPSDNKELPKADTNQLADK 286
+ K VP P K + P+ S+P + PK D D
Sbjct: 635 WLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDL 694
Query: 287 GKLSPHAFK--------TESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSP 338
K +P K T G + P E S+P EP + D P
Sbjct: 695 SK-APEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDK 753
Query: 339 PKEEK 343
PK+ K
Sbjct: 754 PKQPK 758
Score = 41.2 bits (95), Expect = 0.002
Identities = 83/373 (22%), Positives = 133/373 (35%), Gaps = 53/373 (14%)
Query: 25 SVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKS 84
S+ + + + +AG H PG K P P P S + Q P
Sbjct: 937 SIFSQASNLISTAGQPGPHSQSG--PGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSI 994
Query: 85 GAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEA 144
+ +T+ ++ K E K ++ T K + T K P ++ K T + +A
Sbjct: 995 PVKKETKAPAAEK--LEPKAEQAPTVK--------RTETEKKPPPIKDSKSLTAEP-QKA 1043
Query: 145 QTP-----EDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNK-SGADGQTPKDGSSKSG- 197
P P + KT+ + SK T + N+ G P ++
Sbjct: 1044 VLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQE 1103
Query: 198 ---AEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGA----------EEQT 244
QT + + + G ++ P S + P + S+ A +EQ
Sbjct: 1104 WLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQE 1163
Query: 245 SKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKL-----SPHAFKTESG 299
K KV+ E K S K P T+Q ++ KL S K
Sbjct: 1164 VKTEAEKVILE--------KVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLP 1215
Query: 300 EETDLISPPQEEVKSSEPTEDVEPKE--AEDDDTGPE-EGSPPKEEKE---KMSGSASSE 353
EE LI P +E+++S E +E K+ ED PE + S P+E+K K + E
Sbjct: 1216 EEKKLI-PEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEE 1274
Query: 354 NREGTLSDSTGSE 366
EG ++ T E
Sbjct: 1275 KLEGRVAPKTVQE 1287
Score = 37.4 bits (85), Expect = 0.027
Identities = 52/226 (23%), Positives = 82/226 (36%), Gaps = 21/226 (9%)
Query: 118 TTKDSTSKS--HPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTT 175
TT + SKS P+ +PK ++ PE P + K P+ GS +
Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPE--PKKPPPLVK----QPTLHGSPSAKA 720
Query: 176 KDVPNKSGADGQTPKDGSSKSGAEDQTP--KDVPNKSGAEKQTPKDGSNKSGAEEQGPID 233
K P P S +D+ P D P + K T S+ S +
Sbjct: 721 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780
Query: 234 GPSKSGAEEQTSKDSPNKVVPEQPSRK-DHSKPISNPSDNKELPKADTNQLADKGKLSPH 292
+S AEE+T+ P K +PS+ + +P D+K +P+ A K+ H
Sbjct: 781 SKVQSQAEEKTT--PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRP-----ASDSKIISH 833
Query: 293 AFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSP 338
+ + + P Q K EP + + D +GSP
Sbjct: 834 PGPSSESKGQKQVDPVQ---KKEEPKKAQTKMSPKPDAKPMPKGSP 876
Score = 35.0 bits (79), Expect = 0.13
Identities = 52/249 (20%), Positives = 101/249 (40%), Gaps = 40/249 (16%)
Query: 39 NVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKS 98
+++ P R GS+ H TP SP+ S+ + + +P+ E+K Q+ + ++
Sbjct: 1703 SLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHR- 1761
Query: 99 GAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEA 158
G T +DS+ + EL+ ++ + E Q + R +
Sbjct: 1762 ------------PHGPLLPTIEDSSEEE--ELREEEELLKEQ--EKQREIEQQQRKSSSK 1805
Query: 159 KTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPK 218
K++KD K AQ ++ P +TP S+ S ED +P + ++ ++
Sbjct: 1806 KSKKD---KDELRAQRRRERP-------KTPP--SNLSPIEDASPTEELRQAAEMEEL-- 1851
Query: 219 DGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRK-DHSKPISNPSDNKELPK 277
++S E P G E SP K++ Q K + + +P+D + + +
Sbjct: 1852 ---HRSSCSEYSPSIESDPEGFE-----ISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQ 1903
Query: 278 ADTNQLADK 286
+ +Q A K
Sbjct: 1904 KEGSQKALK 1912
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 61.2 bits (147), Expect = 2e-09
Identities = 69/327 (21%), Positives = 129/327 (39%), Gaps = 25/327 (7%)
Query: 70 SSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPE 129
S +E + + +P K + S +E + ++ E + S S+S E
Sbjct: 157 SDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESE-E 215
Query: 130 LQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQK-DSPSKSGSEAQTTKDVPNKSGADGQT 188
L P+ S +S E+ P ++++ ++ P S SE++ D P +D +
Sbjct: 216 LPKPQVSDSES-------EEPPRHQASDSENEELPKPRISDSESE---DPPRHQASDSEN 265
Query: 189 ---PKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGP-----IDGPSKSGA 240
PK S S +ED + E P+ ++S ++GP + S+
Sbjct: 266 EELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQ 325
Query: 241 EEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGE 300
+ ++ DS + E ++ S + D K+ +D+ + K + + GE
Sbjct: 326 KPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGE 385
Query: 301 ETDLISPPQEEVKSSEPTEDVEPKE----AEDDDTGPEEGSPPKEEKEKMSGSASSENRE 356
E + + SE E K+ ++ DD+ + S ++EK S S E
Sbjct: 386 EEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAG 445
Query: 357 GTLSDSTGSEKDDLYPNGSGNGSAESS 383
LSD EK DL+ + S +G+ E +
Sbjct: 446 KELSDKKNEEK-DLFGSDSESGNEEEN 471
Score = 60.5 bits (145), Expect = 3e-09
Identities = 75/334 (22%), Positives = 128/334 (38%), Gaps = 53/334 (15%)
Query: 24 ESVKQEEAGVRPSAGNVSTHPS--LSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTP 81
+ V ++ +G G+V H S R G K H + D P +A E
Sbjct: 31 DDVNEQHSG--SDTGSVERHSENETSDREDGLPKGHHVTDSENDEPLNLNASDSESE--- 85
Query: 82 NKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSG 141
E QKDS ++S A+ S S +E S S+S + P +
Sbjct: 86 -----ELHRQKDSDSESEERAEPP---ASDSENEDVNQHGSDSESEETRKLPGSDSENEE 137
Query: 142 AEAQTPEDSPNR-------SGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSS 194
DS N S +E + + SP+ K P S ++ + P +
Sbjct: 138 LLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALK--PQISDSESEEPPRHQA 195
Query: 195 KSGAEDQTPKDVPNKSGAE-KQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVV 253
++ PK P S +E ++ PK + S +EE P + A + +++ P +
Sbjct: 196 SDSENEEPPK--PRMSDSESEELPKPQVSDSESEE------PPRHQASDSENEELPKPRI 247
Query: 254 PEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVK 313
+ S +D + ++ S+N+ELPK P +ES + PP+ +
Sbjct: 248 SDSES-EDPPRHQASDSENEELPK-------------PRISDSESED------PPRNQAS 287
Query: 314 SSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMS 347
SE E +P+ ++ + GP++G E E S
Sbjct: 288 DSENEELPKPRVSDSESEGPQKGPASDSETEDAS 321
Score = 50.8 bits (120), Expect = 2e-06
Identities = 66/326 (20%), Positives = 118/326 (36%), Gaps = 39/326 (11%)
Query: 49 RPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGS 108
R S + EP P+ S S+S + P+ + S +E + +S+ E K
Sbjct: 192 RHQASDSENEEPPKPRMSDSESE---ELPKPQVSDSESEEPPRHQASDSENEELP--KPR 246
Query: 109 TSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQK-DSPSK 167
S S SE ++ + EL P+ S +S ED P ++++ ++ P
Sbjct: 247 ISDSESEDPPRHQASDSENEELPKPRISDSES-------EDPPRNQASDSENEELPKPRV 299
Query: 168 SGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAE 227
S SE++ + P +D +T K E D NK G + + D +
Sbjct: 300 SDSESEGPQKGP---ASDSETEDASRHKQKPESDDDSDRENK-GEDTEMQNDSFHSDSHM 355
Query: 228 EQGPI---DGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLA 284
++ D + +++ D K E+ K + +S+ D ++ + ++
Sbjct: 356 DRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVS 415
Query: 285 DKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKE 344
D A +SG+ I+ EE + G E EEK+
Sbjct: 416 DADDSDSDAVSDKSGKREKTIASDSEE------------------EAGKELSDKKNEEKD 457
Query: 345 KM-SGSASSENREGTLSDSTGSEKDD 369
S S S E ++D G D+
Sbjct: 458 LFGSDSESGNEEENLIADIFGESGDE 483
Score = 47.8 bits (112), Expect = 2e-05
Identities = 49/214 (22%), Positives = 85/214 (39%), Gaps = 17/214 (7%)
Query: 41 STHPSLSQRPGGSTKSHPEPQ---TPKDSPSKSSA-EAQTPEDTPNKSGAEAKTQKDSSN 96
S P +Q + P+P+ + + P K A +++T + + +K E+ D N
Sbjct: 278 SEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDREN 337
Query: 97 KSGAEAKTQKGS---TSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNR 153
K G + + Q S S + + DS + H + + D K G E E R
Sbjct: 338 K-GEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEE----EKVAKR 392
Query: 154 SGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSK----SGAEDQTPKDVPNK 209
A +D S +++ D + S +D + K G + S +E++ K++ +K
Sbjct: 393 KAAVLSDSEDEEKASAKKSRVVSDADD-SDSDAVSDKSGKREKTIASDSEEEAGKELSDK 451
Query: 210 SGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQ 243
EK S EE D +SG EE+
Sbjct: 452 KNEEKDLFGSDSESGNEEENLIADIFGESGDEEE 485
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/189 (17%), Positives = 78/189 (41%), Gaps = 3/189 (1%)
Query: 44 PSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQK-DSSNKSGAEA 102
P+ +++ +P++ DS ++ E ++ S + +K SS+ E
Sbjct: 311 PASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEH 370
Query: 103 KTQKGSTSKSGSEAQTTKDSTSKSH--PELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKT 160
K QK + + E + K + K+ + + + ++ K +DS + + ++
Sbjct: 371 KKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKSG 430
Query: 161 QKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDG 220
+++ S SE + K++ +K + S E+ D+ +SG E++ G
Sbjct: 431 KREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTG 490
Query: 221 SNKSGAEEQ 229
N+ EE+
Sbjct: 491 FNQEDLEEE 499
Score = 28.9 bits (63), Expect = 9.6
Identities = 23/92 (25%), Positives = 40/92 (43%), Gaps = 8/92 (8%)
Query: 298 SGEETDL--ISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSG------S 349
SG+++D +P Q+E S ED ++ DTG E E ++ G
Sbjct: 7 SGDQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLPKGHHV 66
Query: 350 ASSENREGTLSDSTGSEKDDLYPNGSGNGSAE 381
SEN E +++ SE ++L+ + +E
Sbjct: 67 TDSENDEPLNLNASDSESEELHRQKDSDSESE 98
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.295 0.117 0.309
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,356,006
Number of Sequences: 37866
Number of extensions: 1104209
Number of successful extensions: 13261
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 453
Number of HSP's successfully gapped in prelim test: 1292
Number of HSP's that attempted gapping in prelim test: 5752
Number of HSP's gapped (non-prelim): 5427
length of query: 437
length of database: 18,247,518
effective HSP length: 105
effective length of query: 332
effective length of database: 14,271,588
effective search space: 4738167216
effective search space used: 4738167216
T: 11
A: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 44 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.