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Search of human proteins with 40068466
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
[Homo sapiens]
(2231 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 4602 0.0
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 4420 0.0
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 4410 0.0
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 2036 0.0
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 1783 0.0
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 124 1e-27
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 124 1e-27
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 121 7e-27
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 121 9e-27
gi|57864582 hornerin [Homo sapiens] 119 3e-26
gi|48762934 alpha 2 type I collagen [Homo sapiens] 111 9e-24
gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein ... 111 9e-24
gi|55750053 atrophin-1 [Homo sapiens] 107 1e-22
gi|55750041 atrophin-1 [Homo sapiens] 107 1e-22
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 105 6e-22
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 105 6e-22
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 105 6e-22
gi|62122917 filaggrin family member 2 [Homo sapiens] 104 8e-22
gi|55956910 meningioma 1 [Homo sapiens] 104 8e-22
gi|5453638 AT rich interactive domain 3B [Homo sapiens] 104 1e-21
gi|62865637 AT rich interactive domain 3C (BRIGHT- like) [Homo s... 103 1e-21
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 102 3e-21
gi|163965366 nascent polypeptide-associated complex alpha subuni... 102 3e-21
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 101 9e-21
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 100 2e-20
gi|109255251 loricrin [Homo sapiens] 99 4e-20
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 99 6e-20
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 98 8e-20
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 97 1e-19
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 97 1e-19
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo
sapiens]
Length = 2231
Score = 4602 bits (11937), Expect = 0.0
Identities = 2231/2231 (100%), Positives = 2231/2231 (100%)
Query: 1 METGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQ 60
METGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQ
Sbjct: 1 METGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQ 60
Query: 61 QQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPL 120
QQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPL
Sbjct: 61 QQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPL 120
Query: 121 LSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180
LSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA
Sbjct: 121 LSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180
Query: 181 PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHY 240
PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHY
Sbjct: 181 PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHY 240
Query: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY 300
PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY
Sbjct: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY 300
Query: 301 GGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT 360
GGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT
Sbjct: 301 GGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT 360
Query: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420
LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD
Sbjct: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420
Query: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480
MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ
Sbjct: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480
Query: 481 PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQ 540
PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQ
Sbjct: 481 PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQ 540
Query: 541 PYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQ 600
PYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQ
Sbjct: 541 PYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQ 600
Query: 601 QERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSI 660
QERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSI
Sbjct: 601 QERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSI 660
Query: 661 PGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG 720
PGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG
Sbjct: 661 PGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG 720
Query: 721 FMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQG 780
FMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQG
Sbjct: 721 FMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQG 780
Query: 781 NYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPG 840
NYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPG
Sbjct: 781 NYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPG 840
Query: 841 NMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSG 900
NMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSG
Sbjct: 841 NMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSG 900
Query: 901 LMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKAD 960
LMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKAD
Sbjct: 901 LMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKAD 960
Query: 961 GKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGW 1020
GKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGW
Sbjct: 961 GKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGW 1020
Query: 1021 PKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPL 1080
PKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPL
Sbjct: 1021 PKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPL 1080
Query: 1081 DLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIER 1140
DLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIER
Sbjct: 1081 DLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIER 1140
Query: 1141 GEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPAST 1200
GEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPAST
Sbjct: 1141 GEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPAST 1200
Query: 1201 PHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPN 1260
PHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPN
Sbjct: 1201 PHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPN 1260
Query: 1261 KDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRR 1320
KDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRR
Sbjct: 1261 KDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRR 1320
Query: 1321 HEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSS 1380
HEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSS
Sbjct: 1321 HEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSS 1380
Query: 1381 QQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSE 1440
QQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSE
Sbjct: 1381 QQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSE 1440
Query: 1441 GPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQ 1500
GPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQ
Sbjct: 1441 GPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQ 1500
Query: 1501 RQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSM 1560
RQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSM
Sbjct: 1501 RQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSM 1560
Query: 1561 KMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKITSKDIVTPEAWR 1620
KMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKITSKDIVTPEAWR
Sbjct: 1561 KMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKITSKDIVTPEAWR 1620
Query: 1621 VMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVEYFRKCLIDIFGIL 1680
VMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVEYFRKCLIDIFGIL
Sbjct: 1621 VMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVEYFRKCLIDIFGIL 1680
Query: 1681 MEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEKTESD 1740
MEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEKTESD
Sbjct: 1681 MEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEKTESD 1740
Query: 1741 EKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLGRVQEFNSGLLH 1800
EKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLGRVQEFNSGLLH
Sbjct: 1741 EKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLGRVQEFNSGLLH 1800
Query: 1801 WQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQEGKGDSEEQQEKSIIATID 1860
WQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQEGKGDSEEQQEKSIIATID
Sbjct: 1801 WQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQEGKGDSEEQQEKSIIATID 1860
Query: 1861 DVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLEDEPRSRDETPLCTIAHWQ 1920
DVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLEDEPRSRDETPLCTIAHWQ
Sbjct: 1861 DVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLEDEPRSRDETPLCTIAHWQ 1920
Query: 1921 DSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPERKRAPQTYEKE 1980
DSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPERKRAPQTYEKE
Sbjct: 1921 DSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPERKRAPQTYEKE 1980
Query: 1981 EDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESICLPILDGLLHWMVC 2040
EDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESICLPILDGLLHWMVC
Sbjct: 1981 EDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESICLPILDGLLHWMVC 2040
Query: 2041 PSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFYATLVRY 2100
PSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFYATLVRY
Sbjct: 2041 PSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFYATLVRY 2100
Query: 2101 VGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGVTMAQYQQSQHN 2160
VGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGVTMAQYQQSQHN
Sbjct: 2101 VGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGVTMAQYQQSQHN 2160
Query: 2161 LMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEGRLLDISISAVLNSLVASV 2220
LMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEGRLLDISISAVLNSLVASV
Sbjct: 2161 LMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEGRLLDISISAVLNSLVASV 2220
Query: 2221 ICDVLFQIGQL 2231
ICDVLFQIGQL
Sbjct: 2221 ICDVLFQIGQL 2231
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo
sapiens]
Length = 2178
Score = 4420 bits (11463), Expect = 0.0
Identities = 2159/2232 (96%), Positives = 2162/2232 (96%), Gaps = 55/2232 (2%)
Query: 1 METGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQ 60
METGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQ
Sbjct: 1 METGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQ 60
Query: 61 QQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPL 120
QQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPL
Sbjct: 61 QQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPL 120
Query: 121 LSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180
LSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA
Sbjct: 121 LSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180
Query: 181 PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHY 240
PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHY
Sbjct: 181 PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHY 240
Query: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY 300
PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY
Sbjct: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY 300
Query: 301 GGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT 360
GGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT
Sbjct: 301 GGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT 360
Query: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420
LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD
Sbjct: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420
Query: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480
MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ
Sbjct: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480
Query: 481 PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQ 540
PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQ
Sbjct: 481 PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQ 540
Query: 541 PYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQ 600
PYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQ
Sbjct: 541 PYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQ 600
Query: 601 QERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSI 660
QERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSI
Sbjct: 601 QERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSI 660
Query: 661 PGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG 720
PGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG
Sbjct: 661 PGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG 720
Query: 721 FMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQG 780
FMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQG
Sbjct: 721 FMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQG 780
Query: 781 NYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPG 840
NYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPG
Sbjct: 781 NYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPG 840
Query: 841 NMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSG 900
NMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSG
Sbjct: 841 NMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSG 900
Query: 901 LMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKAD 960
LMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMS
Sbjct: 901 LMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMS------------- 947
Query: 961 GKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGW 1020
PG +P P+ G
Sbjct: 948 ---------------------------PGESKLPLPLKADG--------------KEEGT 966
Query: 1021 PKTPS-SPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKP 1079
P+ S S KSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKP
Sbjct: 967 PQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKP 1026
Query: 1080 LDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIE 1139
LDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIE
Sbjct: 1027 LDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIE 1086
Query: 1140 RGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPAS 1199
RGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPAS
Sbjct: 1087 RGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPAS 1146
Query: 1200 TPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEP 1259
TPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEP
Sbjct: 1147 TPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEP 1206
Query: 1260 NKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDR 1319
NKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDR
Sbjct: 1207 NKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDR 1266
Query: 1320 RHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYS 1379
RHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYS
Sbjct: 1267 RHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYS 1326
Query: 1380 SQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSS 1439
SQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSS
Sbjct: 1327 SQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSS 1386
Query: 1440 EGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVS 1499
EGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVS
Sbjct: 1387 EGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVS 1446
Query: 1500 QRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPS 1559
QRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPS
Sbjct: 1447 QRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPS 1506
Query: 1560 MKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKITSKDIVTPEAW 1619
MKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKITSKDIVTPEAW
Sbjct: 1507 MKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKITSKDIVTPEAW 1566
Query: 1620 RVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVEYFRKCLIDIFGI 1679
RVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVEYFRKCLIDIFGI
Sbjct: 1567 RVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVEYFRKCLIDIFGI 1626
Query: 1680 LMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEKTES 1739
LMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEKTES
Sbjct: 1627 LMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEKTES 1686
Query: 1740 DEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLGRVQEFNSGLL 1799
DEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLGRVQEFNSGLL
Sbjct: 1687 DEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLGRVQEFNSGLL 1746
Query: 1800 HWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQEGKGDSEEQQEKSIIATI 1859
HWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQEGKGDSEEQQEKSIIATI
Sbjct: 1747 HWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQEGKGDSEEQQEKSIIATI 1806
Query: 1860 DDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLEDEPRSRDETPLCTIAHW 1919
DDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLEDEPRSRDETPLCTIAHW
Sbjct: 1807 DDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLEDEPRSRDETPLCTIAHW 1866
Query: 1920 QDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPERKRAPQTYEK 1979
QDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPERKRAPQTYEK
Sbjct: 1867 QDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPERKRAPQTYEK 1926
Query: 1980 EEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESICLPILDGLLHWMV 2039
EEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESICLPILDGLLHWMV
Sbjct: 1927 EEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESICLPILDGLLHWMV 1986
Query: 2040 CPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFYATLVR 2099
CPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFYATLVR
Sbjct: 1987 CPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFYATLVR 2046
Query: 2100 YVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGVTMAQYQQSQH 2159
YVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGVTMAQYQQSQH
Sbjct: 2047 YVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGVTMAQYQQSQH 2106
Query: 2160 NLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEGRLLDISISAVLNSLVAS 2219
NLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEGRLLDISISAVLNSLVAS
Sbjct: 2107 NLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEGRLLDISISAVLNSLVAS 2166
Query: 2220 VICDVLFQIGQL 2231
VICDVLFQIGQL
Sbjct: 2167 VICDVLFQIGQL 2178
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo
sapiens]
Length = 2191
Score = 4410 bits (11439), Expect = 0.0
Identities = 2159/2245 (96%), Positives = 2162/2245 (96%), Gaps = 68/2245 (3%)
Query: 1 METGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQ 60
METGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQ
Sbjct: 1 METGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQ 60
Query: 61 QQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPL 120
QQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPL
Sbjct: 61 QQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPL 120
Query: 121 LSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180
LSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA
Sbjct: 121 LSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180
Query: 181 PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHY 240
PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHY
Sbjct: 181 PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHY 240
Query: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY 300
PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY
Sbjct: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY 300
Query: 301 GGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT 360
GGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT
Sbjct: 301 GGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT 360
Query: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420
LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD
Sbjct: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKD 420
Query: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480
MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ
Sbjct: 421 MGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQ 480
Query: 481 PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQ-------------MPPQYG 527
PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQ MPPQYG
Sbjct: 481 PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYG 540
Query: 528 QQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLA 587
QQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLA
Sbjct: 541 QQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLA 600
Query: 588 PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQS 647
PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQS
Sbjct: 601 PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQS 660
Query: 648 PFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSH 707
PFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSH
Sbjct: 661 PFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSH 720
Query: 708 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSG 767
PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSG
Sbjct: 721 PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSG 780
Query: 768 TYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGR 827
TYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGR
Sbjct: 781 TYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGR 840
Query: 828 MPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQ 887
MPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQ
Sbjct: 841 MPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQ 900
Query: 888 SRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMS 947
SRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMS
Sbjct: 901 SRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMS 960
Query: 948 PGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSF 1007
PG +P P+
Sbjct: 961 ----------------------------------------PGESKLPLPLKADG------ 974
Query: 1008 HGDESDSISSPGWPKTPS-SPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERG 1066
G P+ S S KSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERG
Sbjct: 975 --------KEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERG 1026
Query: 1067 SPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQ 1126
SPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQ
Sbjct: 1027 SPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQ 1086
Query: 1127 YIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMA 1186
YIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMA
Sbjct: 1087 YIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMA 1146
Query: 1187 EVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGM 1246
EVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGM
Sbjct: 1147 EVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGM 1206
Query: 1247 SMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMG 1306
SMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMG
Sbjct: 1207 SMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMG 1266
Query: 1307 QRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPA 1366
QRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPA
Sbjct: 1267 QRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPA 1326
Query: 1367 KRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIP 1426
KRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIP
Sbjct: 1327 KRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIP 1386
Query: 1427 PQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQ 1486
PQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQ
Sbjct: 1387 PQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQ 1446
Query: 1487 RINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLE 1546
RINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLE
Sbjct: 1447 RINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLE 1506
Query: 1547 NRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRR 1606
NRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRR
Sbjct: 1507 NRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRR 1566
Query: 1607 KITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLV 1666
KITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLV
Sbjct: 1567 KITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLV 1626
Query: 1667 EYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEED 1726
EYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEED
Sbjct: 1627 EYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEED 1686
Query: 1727 EEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSD 1786
EEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSD
Sbjct: 1687 EEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSD 1746
Query: 1787 KLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQEGKGD 1846
KLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQEGKGD
Sbjct: 1747 KLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQEGKGD 1806
Query: 1847 SEEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLEDEPR 1906
SEEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLEDEPR
Sbjct: 1807 SEEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLEDEPR 1866
Query: 1907 SRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHE 1966
SRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHE
Sbjct: 1867 SRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHE 1926
Query: 1967 HPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESI 2026
HPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESI
Sbjct: 1927 HPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESI 1986
Query: 2027 CLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPP 2086
CLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPP
Sbjct: 1987 CLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPP 2046
Query: 2087 FSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLE 2146
FSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLE
Sbjct: 2047 FSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLE 2106
Query: 2147 DGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEGRLLD 2206
DGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEGRLLD
Sbjct: 2107 DGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEGRLLD 2166
Query: 2207 ISISAVLNSLVASVICDVLFQIGQL 2231
ISISAVLNSLVASVICDVLFQIGQL
Sbjct: 2167 ISISAVLNSLVASVICDVLFQIGQL 2191
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 2036 bits (5275), Expect = 0.0
Identities = 1219/2416 (50%), Positives = 1443/2416 (59%), Gaps = 431/2416 (17%)
Query: 107 SAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGP 166
+AA +PP PP P + A + E AGG E A + A GP
Sbjct: 8 AAASSLGNPPPPP----PSELKKAEQQQREEAGG--EAAAAAAAERGEMKAAAGQESEGP 61
Query: 167 AAVPE--FNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDP 224
A P A ++GG GG GG A + G PG+
Sbjct: 62 AVGPPQPLGKELQDGAESNGGGGG---------GG-------------AGSGGGPGAEPD 99
Query: 225 LQNSH-EGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGA----- 278
L+NS+ P N+ + P GGGGG G G A G G
Sbjct: 100 LKNSNGNAGPRPALNN--NLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRS 157
Query: 279 -GAVAAAAAAA-------------AAAAGGGGGG--GYGG---SSAGYG----------- 308
AVAAAAAA AA GGGGG Y G +S +G
Sbjct: 158 PSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYP 217
Query: 309 ------------VLSSPRQQGGGMMMGPGGGGAASL-------SKAAAGSAAGGF--QRF 347
LSSPR GG PG G AA+ S A+A S++ F QRF
Sbjct: 218 NRSAYPPPAPAYALSSPR---GGT---PGSGAAAAAGSKPPPSSSASASSSSSSFAQQRF 271
Query: 348 ----------AGQNQHPSGATPTLNQLLTSPSPMMRSY----GGSYPEYSSPSAPPPPPS 393
AG ATPTLNQLLTSPS R Y GG Y P+
Sbjct: 272 GAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSA-RGYQGYPGGDYSGGPQDGGAGKGPA 330
Query: 394 QPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPA-MSPGTPG--- 449
SQ A AAA AA+G AQQRSH A MSPG+ G
Sbjct: 331 DMASQCWGAAAAAAAAAAASG-------------------GAQQRSHHAPMSPGSSGGGG 371
Query: 450 -PTMGRSQ-GSPMDPMVMKRPQLYGMGSNPHSQ-------PQQSSPYPGGSYGPPGPQRY 500
P Q SPMD M RPQ YG G+NP+SQ PQQ YPG YG PQRY
Sbjct: 372 QPLARTPQPSSPMDQMGKMRPQPYG-GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRY 430
Query: 501 PI------------------------------GIQGRTPGAMAGMQYPQQQMPPQYGQQG 530
P+ G QG+TP +PQQQ PP Y QQ
Sbjct: 431 PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPP-YSQQP 489
Query: 531 VS-------GYCQQGQ---------QPYYSQQP-------------------------QP 549
S Y QQ Q QP YSQQP QP
Sbjct: 490 PSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP 549
Query: 550 PHLPPQAQ-----YLPSQ-------------------------SQQRYQPQQDMSQEGYG 579
P+ PQAQ P Q SQQR+ P Q++SQ+ +G
Sbjct: 550 PYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFG 609
Query: 580 TR--SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSS 637
++ S P + K ED+NL Q RPSSLPDLSGSIDDLP GTE LS VS SG +SS
Sbjct: 610 SQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSS 669
Query: 638 QGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQP 697
QG+QSNPAQSPFSPH SPHL I G PSPSPVGSP QSRSGP+SPA++PG+QMPP+P
Sbjct: 670 QGEQSNPAQSPFSPHTSPHLPGIRG-PSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRP 728
Query: 698 PGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGI 757
P QS+S HP+++QS + Q+RG+M QRNPQM QY Q G ++SP GGQ+H G+
Sbjct: 729 PSGQSDSIMHPSMNQSSIAQDRGYM---QRNPQMPQYSSPQPGSALSPRQPSGGQIHTGM 785
Query: 758 SSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGIS---ANNQMHGQ 814
S+QQ NS G+YGPQ QYGPQG Y R P Y+ +P+A+Y G GI+ A QMHGQ
Sbjct: 786 GSYQQ-NSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQ 844
Query: 815 GPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEA 874
P G +P GRM A M NRP+ NM++M P Q G GM PP +NRK QE
Sbjct: 845 PGIPPYGTLPPGRMSHASMGNRPYGPNMANMPP-------QVGSGMCPPPGGMNRKTQET 897
Query: 875 AAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVN 934
A A M AANS Q+R +P MNQ G+M + PY Q +N+ + ++N Q PPYSM M N
Sbjct: 898 AVA-MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMAN 956
Query: 935 SSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVP 994
+SA +MM G+ KL TP + +K
Sbjct: 957 NSAGMAASPEMMGLGDVKL------------TPATKMNNK-------------------- 984
Query: 995 SPMSPSSASISSFHGDESDSISSPGWPKTPS-SPKSSSSTTTGEKITKVYELGNEPERKL 1053
+ G PKT S S KSSSSTTT EKITK+YELG EPERK+
Sbjct: 985 ----------------------ADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKM 1022
Query: 1054 WVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNV 1113
WVDRYL F EE+ +++LPAVG+KPLDL+RLYV VKEIGGL QVNKNKKWRELATNLNV
Sbjct: 1023 WVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNV 1082
Query: 1114 GTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKK-QPKLQPPSPANSGSLQ 1172
GTSSSAASSLKKQYIQ L+AFECKIERGE+PPP++F+ D+KK QPK+QPPSPA SGS+Q
Sbjct: 1083 GTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQ 1142
Query: 1173 GPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQG-GRSSTISVHDPFSDVSDSSFP 1231
GPQTPQST S+SMAE GDLKPPTPASTPH Q+ P+ G RS+++ + D F+D SDS+F
Sbjct: 1143 GPQTPQST-SSSMAE-GGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQ 1200
Query: 1232 KRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDM 1291
KRNSMTPN YQ M+ D+MGRM YEPNKDP+G MRK PGS +PFM+ GQ PN M D
Sbjct: 1201 KRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGS-DPFMSSGQGPNGGMGDP 1259
Query: 1292 YNQSPSGAMSNLGMGQRQQFPYGASYDR-------------------------------- 1319
Y+++ + N+ MG RQ +PYG YDR
Sbjct: 1260 YSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMY 1319
Query: 1320 ---------------RHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQP-NYKRHMDGMYG 1363
RH+ YG Q+ QG PSG P + Q +Y QQ NYKR MDG YG
Sbjct: 1320 SPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSP-FPSQQTTMYQQQQQNYKRPMDGTYG 1378
Query: 1364 PPAKRHEGDMYNMQYS---------------------------SQQQEMYNQYGGSY--- 1393
PPAKRHEG+MY++ YS S QQ++YNQYG +Y
Sbjct: 1379 PPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPAT 1438
Query: 1394 --SGPDRRPI---QGQYPYPYSRERMQGP-GQIQTHGIPPQMMGGPLQSSSSEGPQQNMW 1447
+ +RRP Q Q+P+ + R+R+ P G +PPQMMGGP+Q+S+ Q MW
Sbjct: 1439 ATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMW 1498
Query: 1448 AARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSS 1507
RNDM Y Y NRQ G Q P Y G+NRTD+M+ DQR NHE WPSH +++ PY
Sbjct: 1499 QGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPY-GP 1557
Query: 1508 SASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPS-MKMQKVM 1566
SA + P+TRPP +YQ PPS+ NHI + SPA R +ENR SPSKSPFL S MKMQK
Sbjct: 1558 SAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAG 1617
Query: 1567 PTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKITSKDIVTPEAWRVMMSLK 1626
P VP S + P QPP IRR+ITFPPGSVEA+QPVLKQRR++T KDI TPEAWRVMMSLK
Sbjct: 1618 PPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLK 1677
Query: 1627 SGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVEYFRKCLIDIFGILMEYEVG 1686
SGLLAESTWALDTINILLYDD+++ TFNLSQL G LELLVEYFR+CLI+IFGIL EYEVG
Sbjct: 1678 SGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVG 1737
Query: 1687 DPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEKTESDEKSSIA 1746
DP Q+ L S + G+EEE E + E+EE+EE E+DE+ IA
Sbjct: 1738 DPGQRTLLDPGRFSKVSSPAPMEGGEEEE--ELLGPKLEEEEEEEV----VENDEE--IA 1789
Query: 1747 LTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLGRVQEFNSGLLHWQLGGG 1806
+ D A + K SKFDKLP+KIV+KN+ FVVD SDKLGRVQEF+SGLLHW++GGG
Sbjct: 1790 FSGKDKPASENSEEKLISKFDKLPVKIVQKNDPFVVDCSDKLGRVQEFDSGLLHWRIGGG 1849
Query: 1807 DTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKK--EQEGKGDSEEQQ--------EKSII 1856
DTTEHIQTHFESK E+ P R P P A RK EG + +Q+ EK I
Sbjct: 1850 DTTEHIQTHFESKTELLPSR-PHAPCPPAPRKHVTTAEGTPGTTDQEGPPPDGPPEKRIT 1908
Query: 1857 ATIDDVLSARPGALPEDANPGPQT--ESSKFPFGIQQAKSHRNIKLLEDEPRSRDETPLC 1914
AT+DD+LS R L ED + ESSKFPFGI A+SHRNIK+LEDEP S+DETPLC
Sbjct: 1909 ATMDDMLSTRSSTLTEDGAKSSEAIKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLC 1968
Query: 1915 TIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPERKRAP 1974
T+ WQDSLAKRC+CVSN +RSLSFVPGND EMSKHPGL+LILGKLILLHH+HPERK+AP
Sbjct: 1969 TLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAP 2028
Query: 1975 QTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESICLPILDGL 2034
TYEKEE++D+GV+C+K EWWWDCLE+LR+NTLVTLANISGQLDLS Y ESICLP+LDGL
Sbjct: 2029 LTYEKEEEQDQGVSCNKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGL 2088
Query: 2035 LHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFY 2094
LHW VCPSAEAQDPF T+GPN+VLSPQRLVLETL KLSIQDNNVDLILATPPFSR EK Y
Sbjct: 2089 LHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLY 2148
Query: 2095 ATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGVTMAQY 2154
+T+VR++ DRKNPVCREM++ LL+NLAQGD+LAARAIAVQKGSIGNL+ FLED + Q+
Sbjct: 2149 STMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQF 2208
Query: 2155 QQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEGRLLDISISAVLN 2214
QQSQ +L+HMQ PP EP SVDMM RAA+ALLA+A+VDEN SEF L+E RLLDIS+S ++N
Sbjct: 2209 QQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISVSPLMN 2268
Query: 2215 SLVASVICDVLFQIGQ 2230
SLV+ VICDVLF IGQ
Sbjct: 2269 SLVSQVICDVLFLIGQ 2284
Score = 59.7 bits (143), Expect = 3e-08
Identities = 248/1182 (20%), Positives = 347/1182 (29%), Gaps = 267/1182 (22%)
Query: 16 EAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHP 75
+ P+ PPHQQ A + QQ Q Q Q QQQQ Q P
Sbjct: 520 QQPSQPPHQQSP-----------APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQP 568
Query: 76 ISNNNSLGGAGGGAPQPGPDMEQ---------PQHGGAKDSAAGGQADPPGPPLLSKPGD 126
+ S A PQP Q P + G QA SK G
Sbjct: 569 APSTLSQQAA---YPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQ 625
Query: 127 ED-----DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPG-----GGGGPAAVPEFNNYY 176
ED + P G + +G G P V+ G G A F+ +
Sbjct: 626 EDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHT 685
Query: 177 GSAAPASGGPG----GRAGPCFDQHGGQQSPGM--GMMHSASAAAAGAPGSMDPLQN--- 227
P GP G G SP G + + M P N
Sbjct: 686 SPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSS 745
Query: 228 --SHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGG--------------GSGGGGGGGGA 271
GY P YS P G GG GS G GG
Sbjct: 746 IAQDRGYMQRN-PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYG 804
Query: 272 GAGG----AGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG------YGVL----------- 310
GG A+ A +A AGG G GG G YG L
Sbjct: 805 PQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMG 864
Query: 311 ---------SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTL 361
+ P Q G GM PGG + A A A + QN+ P P +
Sbjct: 865 NRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAAN----SIQNRPP--GYPNM 918
Query: 362 NQLLTSPSPMMRSYGGSYPEY----SSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGL 417
NQ MM G+ P Y +S + P P S + G A+ M
Sbjct: 919 NQ-----GGMM----GTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEM-- 967
Query: 418 GKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP 477
MG +PA + + GTP + S K +LY +G P
Sbjct: 968 ---MGLGDVKLTPATKMNNK------ADGTPKTESKSKKSSSSTTTNEKITKLYELGGEP 1018
Query: 478 HSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQ 537
+ G P GR P + + ++ + G Q
Sbjct: 1019 ERKMWVDRYLAFTEEKAMGMTNLP--AVGRKPLDLYRLYVSVKE---------IGGLTQV 1067
Query: 538 GQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQ--------------PQQDMSQEGYGTRSQ 583
+ + + ++ + S +Q Q P D+ +SQ
Sbjct: 1068 NKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQ 1127
Query: 584 PPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATL-------------SSAVS 630
P + P P ++ + P S DL T A+ S++V
Sbjct: 1128 PKIQPPSPAGSG-SMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVG 1186
Query: 631 ASGSTSSQGDQSNPAQSPFSPH----ASPHLSSIPGGPSPSPVGSPVGSNQSRSG----- 681
+ + D + ++ +P+ S + S + G S P P GS + G
Sbjct: 1187 IQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFM 1246
Query: 682 ------------PISPASIPG---SQMPPQ--------------PPGSQSE---SSSHPA 709
P S A+ PG M P+ PG E S+ P
Sbjct: 1247 SSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQ 1306
Query: 710 LSQSPMPQERGFMAGTQRNPQMAQ--------YGPQ---QTGPSMSPHPSPGGQMHAGIS 758
+ P + G + ++ PQ Q YG Q Q PS SP PS M+
Sbjct: 1307 PNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQ 1366
Query: 759 SFQQSNSSGTYGPQMSQY-------------GPQGNYSRPPAYSGVPSASYSGPGPGMGI 805
+ GTYGP ++ G PPA P++ P
Sbjct: 1367 QNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPA-QPQPASQQQAAQPSPQQ 1425
Query: 806 SANNQMHGQGPSQPCGAVPLGRMPSAGMQNR-PF--------------------PGNMSS 844
NQ P+ A R P+ G QN+ PF P M
Sbjct: 1426 DVYNQYGNAYPATATAATE--RRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGG 1483
Query: 845 MTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSF----PGMNQSG 900
+S ++QQG G T N +++ + Q A +R N G
Sbjct: 1484 PIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEG 1543
Query: 901 LMASSSPYSQPMNNSSSLMNTQAPP---YSMAPAMVNSSAASVGLADMMSPGESKLPLPL 957
S P S+ + PP Y P+M N + + SP PLP
Sbjct: 1544 SWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNH------IPQVSSPA----PLPR 1593
Query: 958 KADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSP 999
+ + + P S G PP P + P+P+ P
Sbjct: 1594 PMENRTSPSKSPFLHSGMKMQKAG---PPVPASHIAPAPVQP 1632
Score = 55.1 bits (131), Expect = 8e-07
Identities = 223/1068 (20%), Positives = 330/1068 (30%), Gaps = 182/1068 (17%)
Query: 21 PPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQ-----------QQQQQQQQQQQQ 69
PP+ Q + ++ H QQQ QQ QQQ Q Q Q
Sbjct: 452 PPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQL 511
Query: 70 QQQQHPISNNNSL-GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDED 128
Q Q P S S AP P QH ++ + QA P + +
Sbjct: 512 QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP----YQQQQPQQ 567
Query: 129 DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGG 188
AP + + A Y P +QQ P + +GS A +
Sbjct: 568 PAPSTLSQQAA--YPQP-----QSQQSQQTAYSQQRFPPPQELSQDSFGSQASS------ 614
Query: 189 RAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGA 248
A GGQ+ + + S ++ GS+D L EG + PG S G
Sbjct: 615 -APSMTSSKGGQEDMNLS-LQSRPSSLPDLSGSIDDLPMGTEGALS------PGVSTSGI 666
Query: 249 GGGGGGGGGGGGGSGGGGGGGG-AGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307
G G G V + A+ A + +G G+
Sbjct: 667 SSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQ--- 723
Query: 308 GVLSSPRQQGG--GMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLL 365
PR G +M P S+++++ G QR Q P ++P L
Sbjct: 724 ---MPPRPPSGQSDSIMHP------SMNQSSIAQDRGYMQR---NPQMPQYSSPQPGSAL 771
Query: 366 TSPSP---------------MMRSYGGSYPEYSSPSAPPPPPSQ---PQSQAAAAGAAAG 407
+ P M SYG +Y P P+ P + +AG A G
Sbjct: 772 SPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGG 831
Query: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR---SQGSPMDPM- 463
MG G M Q + SH +M GP M GS M P
Sbjct: 832 ----INPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887
Query: 464 --VMKRPQLYGMGSNPHSQPQQSSP--YP----GGSYGPPGPQRYPIGIQGRTPGAMAGM 515
+ ++ Q + + + Q+ P YP GG G P G+ +MAGM
Sbjct: 888 GGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPP-------YGQGINSMAGM 940
Query: 516 QYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQ 575
PQ P Y G G + P+ + + P M+
Sbjct: 941 INPQ---GPPYSMGGTMANNSAGM----AASPE----------MMGLGDVKLTPATKMNN 983
Query: 576 EGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGST 635
+ GT P K + E+ + L +L G + + A G T
Sbjct: 984 KADGT----PKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMT 1039
Query: 636 SSQGDQSNPA---QSPFSPHASPHLSSIPGGPSPSPVGS--PVGSNQSRSGPISPASIP- 689
+ P + S L+ + + + VG++ S + + I
Sbjct: 1040 NLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQC 1099
Query: 690 ----------GSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQT 739
G PP + S P + Q P P G M G Q PQ +
Sbjct: 1100 LYAFECKIERGEDPPPDIFAAADSKKSQPKI-QPPSPAGSGSMQGPQ-TPQSTSSSMAEG 1157
Query: 740 G------PSMSPH----PSPGGQMHAGI-----------SSFQQSNS---SGTYGPQMSQ 775
G P+ +PH P PG + S+FQ+ NS + Y P M+
Sbjct: 1158 GDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNT 1217
Query: 776 YGPQGNYSRPP---AYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAG 832
G S P Y + A S P G N M G S+ G LG +
Sbjct: 1218 SDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGM-GDPYSRAAGP-GLGNVAMGP 1275
Query: 833 MQNRPFPGNMSSMTPSSPGMSQQGGPGMGPP----MPTVNRKAQEAAAAVMQAAANSAQS 888
Q+ P+ G + + PG+ +G G P MP+ + + Q
Sbjct: 1276 RQHYPYGGPYDRVR-TEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQ 1334
Query: 889 RQGSFPGMNQSGLMASSSPY---------SQPMNNSSSLMNTQAPPYSMAPAMVNSSAAS 939
R S+ + S SP+ Q N + T PP + S S
Sbjct: 1335 RHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYS 1394
Query: 940 VGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPT 987
G P + +LP ++ QP S +D Y+ G + P T
Sbjct: 1395 TGQG---QPQQQQLPPAQPQPASQQQAAQP-SPQQDVYNQYGNAYPAT 1438
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 1783 bits (4618), Expect = 0.0
Identities = 1120/2332 (48%), Positives = 1329/2332 (56%), Gaps = 480/2332 (20%)
Query: 107 SAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGP 166
+AA +PP PP P + A + E AGG E A + A GP
Sbjct: 8 AAASSLGNPPPPP----PSELKKAEQQQREEAGG--EAAAAAAAERGEMKAAAGQESEGP 61
Query: 167 AAVPE--FNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDP 224
A P A ++GG GG GG A + G PG+
Sbjct: 62 AVGPPQPLGKELQDGAESNGGGGG---------GG-------------AGSGGGPGAEPD 99
Query: 225 LQNSH-EGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGA----- 278
L+NS+ P N+ + P GGGGG G G A G G
Sbjct: 100 LKNSNGNAGPRPALNN--NLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRS 157
Query: 279 -GAVAAAAAAA-------------AAAAGGGGGG--GYGG---SSAGYG----------- 308
AVAAAAAA AA GGGGG Y G +S +G
Sbjct: 158 PSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYP 217
Query: 309 ------------VLSSPRQQGGGMMMGPGGGGAASL-------SKAAAGSAAGGF--QRF 347
LSSPR GG PG G AA+ S A+A S++ F QRF
Sbjct: 218 NRSAYPPPAPAYALSSPR---GGT---PGSGAAAAAGSKPPPSSSASASSSSSSFAQQRF 271
Query: 348 ----------AGQNQHPSGATPTLNQLLTSPSPMMRSY----GGSYPEYSSPSAPPPPPS 393
AG ATPTLNQLLTSPS R Y GG Y P+
Sbjct: 272 GAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSA-RGYQGYPGGDYSGGPQDGGAGKGPA 330
Query: 394 QPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPA-MSPGTPG--- 449
SQ A AAA AA+G AQQRSH A MSPG+ G
Sbjct: 331 DMASQCWGAAAAAAAAAAASG-------------------GAQQRSHHAPMSPGSSGGGG 371
Query: 450 -PTMGRSQ-GSPMDPMVMKRPQLYGMGSNPHSQ-------PQQSSPYPGGSYGPPGPQRY 500
P Q SPMD M RPQ YG G+NP+SQ PQQ YPG YG PQRY
Sbjct: 372 QPLARTPQPSSPMDQMGKMRPQPYG-GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRY 430
Query: 501 PI------------------------------GIQGRTPGAMAGMQYPQQQMPPQYGQQG 530
P+ G QG+TP +PQQQ PP Y QQ
Sbjct: 431 PMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPP-YSQQP 489
Query: 531 VS-------GYCQQGQ---------QPYYSQQP-------------------------QP 549
S Y QQ Q QP YSQQP QP
Sbjct: 490 PSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP 549
Query: 550 PHLPPQAQ-----YLPSQ-------------------------SQQRYQPQQDMSQEGYG 579
P+ PQAQ P Q SQQR+ P Q++SQ+ +G
Sbjct: 550 PYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFG 609
Query: 580 TR--SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSS 637
++ S P + K ED+NL Q RPSSLPDLSGSIDDLP GTE LS VS SG +SS
Sbjct: 610 SQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSS 669
Query: 638 QGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQP 697
QG+QSNPAQSPFSPH SPHL I G PSPSPVGSP QSRSGP+SPA++PG+QMPP+P
Sbjct: 670 QGEQSNPAQSPFSPHTSPHLPGIRG-PSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRP 728
Query: 698 PGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGI 757
P QS+S HP+++QS + Q+RG+M QRNPQM QY Q G ++SP GGQ+H G+
Sbjct: 729 PSGQSDSIMHPSMNQSSIAQDRGYM---QRNPQMPQYSSPQPGSALSPRQPSGGQIHTGM 785
Query: 758 SSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGIS---ANNQMHGQ 814
S+QQ NS G+YGPQ QYGPQG Y R P Y+ +P+A+Y G GI+ A QMHGQ
Sbjct: 786 GSYQQ-NSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQ 844
Query: 815 GPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEA 874
P G +P GRM A M NRP+ NM++M P Q G GM PP +NRK QE
Sbjct: 845 PGIPPYGTLPPGRMSHASMGNRPYGPNMANMPP-------QVGSGMCPPPGGMNRKTQET 897
Query: 875 AAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVN 934
A A M AANS Q+R +P MNQ G+M + PY Q +N+ + ++N Q PPYSM M N
Sbjct: 898 AVA-MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGINSMAGMINPQGPPYSMGGTMAN 956
Query: 935 SSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVP 994
+SA +MM G+ KL TP + +K
Sbjct: 957 NSAGMAASPEMMGLGDVKL------------TPATKMNNK-------------------- 984
Query: 995 SPMSPSSASISSFHGDESDSISSPGWPKTPS-SPKSSSSTTTGEKITKVYELGNEPERKL 1053
+ G PKT S S KSSSSTTT EKITK+YELG EPERK+
Sbjct: 985 ----------------------ADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKM 1022
Query: 1054 WVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNV 1113
WVDRYL F EE+ +++LPAVG+KPLDL+RLYV VKEIGGL QVNKNKKWRELATNLNV
Sbjct: 1023 WVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNV 1082
Query: 1114 GTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKK-QPKLQPPSPANSGSLQ 1172
GTSSSAASSLKKQYIQ L+AFECKIERGE+PPP++F+ D+KK QPK+QPPSPA SGS+Q
Sbjct: 1083 GTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQ 1142
Query: 1173 GPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQG-GRSSTISVHDPFSDVSDSSFP 1231
GPQTPQST S+SMAE GDLKPPTPASTPH Q+ P+ G RS+++ + D F+D SDS+F
Sbjct: 1143 GPQTPQST-SSSMAE-GGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQ 1200
Query: 1232 KRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDM 1291
KRNSMTPN YQ M+ D+MGRM YEPNKDP+G MRK PG S+PFM+ GQ PN M D
Sbjct: 1201 KRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPG-SDPFMSSGQGPNGGMGDP 1259
Query: 1292 YNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQ 1351
Y+++ + N+ MG RQ +PYG YDR + PG G P G G QP L P
Sbjct: 1260 YSRAAGPGLGNVAMGPRQHYPYGGPYDR-----VRTEPGIG-PEGNMSTGAPQPNLMPSN 1313
Query: 1352 PNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSR 1411
P+ GMY P Y Q QQQ+ ++ YG +S
Sbjct: 1314 PD-----SGMYSP-------SRYPPQQQQQQQQRHDSYGNQFS----------------- 1344
Query: 1412 ERMQGPGQIQTHGIPPQMMGGPLQS-SSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAP 1470
T G P G P S ++ QQ ++ +P P +NR P
Sbjct: 1345 ----------TQGTP---SGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSP------- 1384
Query: 1471 PYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPN 1530
+ P++ S MQ PP P+ +
Sbjct: 1385 -----------------------------SKSPFLHSGMKMQK-AGPPVPA--------S 1406
Query: 1531 HISRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITF 1590
HI+ AP V P + +T PP
Sbjct: 1407 HIAPAP----------------------------VQPPMIRRDITFPP------------ 1426
Query: 1591 PPGSVEASQPVLKQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTV 1650
GSVEA+QPVLKQRR++T KDI TPEAWRVMMSLKSGLLAESTWALDTINILLYDD+++
Sbjct: 1427 --GSVEATQPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSI 1484
Query: 1651 ATFNLSQLSGFLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDS 1710
TFNLSQL G LELLVEYFR+CLI+IFGIL EYEVGDP Q+ L S +
Sbjct: 1485 MTFNLSQLPGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTLLDPGRFSKVSSPAPMEG 1544
Query: 1711 GKEEEDAECIDDDEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLP 1770
G+EEE E + E+EE+E E E+DE+ IA + D A + K SKFDKLP
Sbjct: 1545 GEEEE--ELLGPKLEEEEEE----EVVENDEE--IAFSGKDKPASENSEEKLISKFDKLP 1596
Query: 1771 IKIVKKNNLFVVDRSDKLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPP 1830
+KIV+KN+ FVVD SDKLGRVQEF+SGLLHW++GGGDTTEHIQTHFESK E+ P RP
Sbjct: 1597 VKIVQKNDPFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKTELLP-SRPHA 1655
Query: 1831 PLSSAGRK--KEQEGKGDSEEQQ--------EKSIIATIDDVLSARPGALPEDANPGPQT 1880
P A RK EG + +Q+ EK I AT+DD+LS R L ED +
Sbjct: 1656 PCPPAPRKHVTTAEGTPGTTDQEGPPPDGPPEKRITATMDDMLSTRSSTLTEDGAKSSEA 1715
Query: 1881 --ESSKFPFGIQQAKSHRNIKLLEDEPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLS 1938
ESSKFPFGI A+SHRNIK+LEDEP S+DETPLCT+ WQDSLAKRC+CVSN +RSLS
Sbjct: 1716 IKESSKFPFGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLS 1775
Query: 1939 FVPGNDAEMSKHPGLVLILGKLILLHHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDC 1998
FVPGND EMSKHPGL+LILGKLILLHH+HPERK+AP TYEKEE++D+GV+C+K EWWWDC
Sbjct: 1776 FVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDC 1835
Query: 1999 LEVLRDNTLVTLANISGQLDLSAYTESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVL 2058
LE+LR+NTLVTLANISGQLDLS Y ESICLP+LDGLLHW VCPSAEAQDPF T+GPN+VL
Sbjct: 1836 LEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVL 1895
Query: 2059 SPQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLS 2118
SPQRLVLETL KLSIQDNNVDLILATPPFSR EK Y+T+VR++ DRKNPVCREM++ LL+
Sbjct: 1896 SPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLA 1955
Query: 2119 NLAQGDALAARAIAVQKGSIGNLISFLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMC 2178
NLAQGD+LAARAIAVQKGSIGNL+ FLED + Q+QQSQ +L+HMQ PP EP SVDMM
Sbjct: 1956 NLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMR 2015
Query: 2179 RAAKALLAMARVDENRSEFLLHEGRLLDISISAVLNSLVASVICDVLFQIGQ 2230
RAA+ALLA+A+VDEN SEF L+E RLLDIS+S ++NSLV+ VICDVLF IGQ
Sbjct: 2016 RAARALLALAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQ 2067
Score = 53.1 bits (126), Expect = 3e-06
Identities = 224/1015 (22%), Positives = 302/1015 (29%), Gaps = 218/1015 (21%)
Query: 16 EAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHP 75
+ P+ PPHQQ A + QQ Q Q Q QQQQ Q P
Sbjct: 520 QQPSQPPHQQSP-----------APYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQP 568
Query: 76 ISNNNSLGGAGGGAPQPGPDMEQ---------PQHGGAKDSAAGGQADPPGPPLLSKPGD 126
+ S A PQP Q P + G QA SK G
Sbjct: 569 APSTLSQQAA---YPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQ 625
Query: 127 ED-----DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPG-----GGGGPAAVPEFNNYY 176
ED + P G + +G G P V+ G G A F+ +
Sbjct: 626 EDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHT 685
Query: 177 GSAAPASGGPG----GRAGPCFDQHGGQQSPGM--GMMHSASAAAAGAPGSMDPLQN--- 227
P GP G G SP G + + M P N
Sbjct: 686 SPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSS 745
Query: 228 --SHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGG--------------GSGGGGGGGGA 271
GY P YS P G GG GS G GG
Sbjct: 746 IAQDRGYMQRN-PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYG 804
Query: 272 GAGG----AGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG------YGVL----------- 310
GG A+ A +A AGG G GG G YG L
Sbjct: 805 PQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMG 864
Query: 311 ---------SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTL 361
+ P Q G GM PGG + A A A + QN+ P P +
Sbjct: 865 NRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAAN----SIQNRPP--GYPNM 918
Query: 362 NQLLTSPSPMMRSYGGSYPEY----SSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGL 417
NQ MM G+ P Y +S + P P S + G A+ M
Sbjct: 919 NQ-----GGMM----GTGPPYGQGINSMAGMINPQGPPYSMGGTMANNSAGMAASPEM-- 967
Query: 418 GKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP 477
MG +PA + + GTP + S K +LY +G P
Sbjct: 968 ---MGLGDVKLTPATKMNNK------ADGTPKTESKSKKSSSSTTTNEKITKLYELGGEP 1018
Query: 478 HSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQ 537
+ G P GR P + + ++ + G Q
Sbjct: 1019 ERKMWVDRYLAFTEEKAMGMTNLP--AVGRKPLDLYRLYVSVKE---------IGGLTQV 1067
Query: 538 GQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQ--------------PQQDMSQEGYGTRSQ 583
+ + + ++ + S +Q Q P D+ +SQ
Sbjct: 1068 NKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQ 1127
Query: 584 PPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSN 643
P + P PS P SGS+ P ++T S S + GD
Sbjct: 1128 PKIQP---------------PS--PAGSGSMQG-PQTPQST-------SSSMAEGGDLKP 1162
Query: 644 PAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSE 703
P +P ++PH S IP P G ++S S I A GS Q S +
Sbjct: 1163 P-----TPASTPH-SQIPPLP---------GMSRSNSVGIQDAFNDGSDSTFQKRNSMTP 1207
Query: 704 SSSH-PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQ 762
+ + P+++ S M M P YG + P P S G + G+
Sbjct: 1208 NPGYQPSMNTSDM------MGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGD-PY 1260
Query: 763 SNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQP-CG 821
S ++G G GP+ +Y Y V + G GP +S PS P G
Sbjct: 1261 SRAAGP-GLGNVAMGPRQHYPYGGPYDRV--RTEPGIGPEGNMSTGAPQPNLMPSNPDSG 1317
Query: 822 AVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQA 881
R P Q + S QG P G P P+ Q
Sbjct: 1318 MYSPSRYPPQQQQQQ-----QQRHDSYGNQFSTQGTPS-GSPFPS-------------QQ 1358
Query: 882 AANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPY---SMAPAMV 933
Q +Q S P + +SP P +S M PP +APA V
Sbjct: 1359 TTMYQQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPV 1413
Score = 51.2 bits (121), Expect = 1e-05
Identities = 219/1067 (20%), Positives = 324/1067 (30%), Gaps = 191/1067 (17%)
Query: 21 PPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQ-----------QQQQQQQQQQQQ 69
PP+ Q + ++ H QQQ QQ QQQ Q Q Q
Sbjct: 452 PPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQL 511
Query: 70 QQQQHPISNNNSL-GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDED 128
Q Q P S S AP P QH ++ + QA P + +
Sbjct: 512 QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP----YQQQQPQQ 567
Query: 129 DAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGG 188
AP + + A Y P +QQ P + +GS A +
Sbjct: 568 PAPSTLSQQAA--YPQP-----QSQQSQQTAYSQQRFPPPQELSQDSFGSQASS------ 614
Query: 189 RAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGA 248
A GGQ+ + + S ++ GS+D L EG + PG S G
Sbjct: 615 -APSMTSSKGGQEDMNLS-LQSRPSSLPDLSGSIDDLPMGTEGALS------PGVSTSGI 666
Query: 249 GGGGGGGGGGGGGSGGGGGGGG-AGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307
G G G V + A+ A + +G G+
Sbjct: 667 SSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQ--- 723
Query: 308 GVLSSPRQQGG--GMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLL 365
PR G +M P S+++++ G QR Q P ++P L
Sbjct: 724 ---MPPRPPSGQSDSIMHP------SMNQSSIAQDRGYMQR---NPQMPQYSSPQPGSAL 771
Query: 366 TSPSP---------------MMRSYGGSYPEYSSPSAPPPPPSQ---PQSQAAAAGAAAG 407
+ P M SYG +Y P P+ P + +AG A G
Sbjct: 772 SPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGG 831
Query: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR---SQGSPMDPM- 463
MG G M Q + SH +M GP M GS M P
Sbjct: 832 ----INPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPP 887
Query: 464 --VMKRPQLYGMGSNPHSQPQQSSP--YP----GGSYGPPGPQRYPIGIQGRTPGAMAGM 515
+ ++ Q + + + Q+ P YP GG G P G+ +MAGM
Sbjct: 888 GGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTGPP-------YGQGINSMAGM 940
Query: 516 QYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQ 575
PQ P Y G G + P+ + + P M+
Sbjct: 941 INPQ---GPPYSMGGTMANNSAGM----AASPE----------MMGLGDVKLTPATKMNN 983
Query: 576 EGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGST 635
+ GT P K + E+ + L +L G + + A G T
Sbjct: 984 KADGT----PKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMT 1039
Query: 636 SSQGDQSNPA---QSPFSPHASPHLSSIPGGPSPSPVGS--PVGSNQSRSGPISPASIP- 689
+ P + S L+ + + + VG++ S + + I
Sbjct: 1040 NLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQC 1099
Query: 690 ----------GSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQT 739
G PP + S P + Q P P G M G Q PQ +
Sbjct: 1100 LYAFECKIERGEDPPPDIFAAADSKKSQPKI-QPPSPAGSGSMQGPQ-TPQSTSSSMAEG 1157
Query: 740 G------PSMSPH----PSPGGQMHAGI-----------SSFQQSNS---SGTYGPQMSQ 775
G P+ +PH P PG + S+FQ+ NS + Y P M+
Sbjct: 1158 GDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNT 1217
Query: 776 YGPQGNYSRPP---AYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAG 832
G S P Y + A S P G N M G S+ G LG +
Sbjct: 1218 SDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGM-GDPYSRAAGP-GLGNVAMGP 1275
Query: 833 MQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGS 892
Q+ P+ G + + PG+ +G G P P +M + +S
Sbjct: 1276 RQHYPYGGPYDRVR-TEPGIGPEGNMSTGAPQPN-----------LMPSNPDSGMYSPSR 1323
Query: 893 FPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESK 952
+P Q Y N S+ P+ + V S
Sbjct: 1324 YPPQQQQQQQQRHDSYG---NQFSTQGTPSGSPFPSQQTTMYQQQQQV---------SSP 1371
Query: 953 LPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSP 999
PLP + + + P S G PP P + P+P+ P
Sbjct: 1372 APLPRPMENRTSPSKSPFLHSGMKMQKAG---PPVPASHIAPAPVQP 1415
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 124 bits (311), Expect = 1e-27
Identities = 263/1079 (24%), Positives = 349/1079 (32%), Gaps = 193/1079 (17%)
Query: 59 QQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADP--- 115
Q Q +Q + Q+ P + +G G PQ GP EQ G D G P
Sbjct: 24 QGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQ-GPAGEQGPRGDRGDKGEKGAPGPRGR 82
Query: 116 ---------PGPPLLSKPGDEDDAPPKMG-----EPAGGRYEHPGLGALGTQQPPVAV-- 159
PGPP PG PP +G + AGG E G LG Q P+
Sbjct: 83 DGEPGTPGNPGPP--GPPGPP--GPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMG 138
Query: 160 PGGGGGPAAVPEFNNYYGSAA----PASGGPGGRAGPCF-------DQHGGQQSPGMGMM 208
P G GPA P + G+ P GP G GP D G+
Sbjct: 139 PRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERG 198
Query: 209 HSASAAAAGAPGSMD-PLQNSHEGYPNSQC-------------------NHYPG----YS 244
A G PG+ P H GYP N PG
Sbjct: 199 PPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRG 258
Query: 245 RPGAGG--GGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG 302
PG G G G G G G G G G G G A A AG G G G
Sbjct: 259 LPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEG 318
Query: 303 SSAGYGVLSSPRQQG-GGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQN--QHPSGATP 359
+ G +P G G PG G +A G F G P GAT
Sbjct: 319 AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATG 378
Query: 360 TLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAA--GGQQAAAGMGL 417
L + P + + G P P+ PQ AG G + G+G
Sbjct: 379 PLGPKGQTGEPGIAGFKGEQGPKGEPG-----PAGPQGAPGPAGEEGKRGARGEPGGVGP 433
Query: 418 GKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPT-MGRSQGSPMDPMVMKRPQLYGM--- 473
G + A + + + P +PG GP+ + +G+ DP P L G
Sbjct: 434 IGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGL 493
Query: 474 -GSNPHSQPQ-----QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQ--QQMPPQ 525
G + PQ +P G GPPGPQ G +G+ PG M G P+ P +
Sbjct: 494 TGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ----GARGQ-PGVM-GFPGPKGANGEPGK 547
Query: 526 YGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPP 585
G++G+ G P + LP + + G R +
Sbjct: 548 AGEKGLPG-------------------APGLRGLPGKDGETGAAGPPGPAGPAGERGEQG 588
Query: 586 LAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNP- 644
APG + L P P G D EA V G G++ +P
Sbjct: 589 -APGPSGFQGL-----PGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG 642
Query: 645 AQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSES 704
AQ P P PG P + SGP P PG+Q PPG Q
Sbjct: 643 AQGLQGPRGLP---GTPGTDGP----------KGASGPAGP---PGAQ---GPPGLQGMP 683
Query: 705 SSHPALSQSPMPQERGFMAGTQRNPQMA---QYGPQQTGPSMSPHPSPGGQMHAGISSFQ 761
A + +RG + ++ P+ A G TGP P P+ +
Sbjct: 684 GERGAAGIAGPKGDRGDVG--EKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPG 741
Query: 762 QSNSSGTYGP--QMSQYGPQG--NYSRPPAYSGVPSAS-----------YSGPGPGMGIS 806
+ S+G G + + GP G ++ PP G P A PGP
Sbjct: 742 PAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGP----- 796
Query: 807 ANNQMHGQGPSQPCGAVPLGRMPSAGMQNRP----FPGNMSSMTPSSPGMSQQGGPGMGP 862
GP P G G + G Q P FPG + P PG + GP GP
Sbjct: 797 -QGPSGAPGPQGPTGVT--GPKGARGAQGPPGATGFPGAAGRVGP--PGSNGNPGPP-GP 850
Query: 863 PMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQ 922
P P+ A +S + PG+ G +P ++ S +
Sbjct: 851 PGPS-------GKDGPKGARGDSGPPGRAGEPGLQ--GPAGPPGEKGEPGDDGPS--GAE 899
Query: 923 APPYSMAPAMVNSSAASVGLADMMSP-GESKLPLPLKADGKEEGTP--QPESKSKDSYSS 979
PP P + VGL G LP P GK+ G P +
Sbjct: 900 GPP---GPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQ-GAPGASGDRGPPGPVGP 955
Query: 980 QGISQPP-TPGNLPVPSPMSP----SSASISSFHGDESDSISSPGWPKTPSSPKSSSST 1033
G++ P PG P P +A + G E+ ++ +PG P P SP + T
Sbjct: 956 PGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRG-ETGAVGAPGAPGPPGSPGPAGPT 1013
Score = 112 bits (281), Expect = 3e-24
Identities = 180/642 (28%), Positives = 213/642 (33%), Gaps = 94/642 (14%)
Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS-KPGDEDDAPPKMGEPA--GG 140
GA G GP E+ + G S G PPGPP KPGD+ P + G P G
Sbjct: 570 GAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQG-VPGEAGAPGLVGP 628
Query: 141 RYEHPGLGALGTQQPPVAVPGGGG--GPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHG 198
R E G G+ PG G GP +P P + GP G +GP G
Sbjct: 629 RGERGFPGERGS-------PGAQGLQGPRGLP--------GTPGTDGPKGASGPA-GPPG 672
Query: 199 GQQSPGMGMMHSASAAA--AGAPGSM-DPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGG 255
Q PG+ M AA AG G D + EG P G + P G G
Sbjct: 673 AQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGR--GLTGPIGPPGPAGA 730
Query: 256 GGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQ 315
G G G G G AGA GA A AG G G G+ G
Sbjct: 731 NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD 790
Query: 316 QGGGMMMGPGGG-GAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRS 374
G GP G G + A G Q G P A
Sbjct: 791 AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAA----------------- 833
Query: 375 YGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAA-GGQQAAAGMGLGKDMGAQYAAASPAWA 433
G P S+ + PP P P + GA G AG + G Q A P
Sbjct: 834 -GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAG-----EPGLQGPAGPPGEK 887
Query: 434 AAQQRSHPAMSPGTPGPTMGRSQ----GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPG 489
P+ + G PGP Q G P P L G P +Q +P
Sbjct: 888 GEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPG---KQGAPGAS 944
Query: 490 GSYGPPGPQRYPIGIQGRTPGAMAGMQ-YPQQQMPP-QYGQQGVSGYCQQGQQPYYSQQP 547
G GPPGP P G+ G P G + P PP + G GV G + P
Sbjct: 945 GDRGPPGPVGPP-GLTG--PAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAP 1001
Query: 548 QPPHLPPQAQYLPSQSQQ-RYQPQQDMSQEG-YGTRS-QPPLAP-------GKPNHEDLN 597
PP P A Q + Q M G G R Q P P G+P L
Sbjct: 1002 GPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLK 1061
Query: 598 LIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHL 657
+ L L G P G S ASG G + P P P
Sbjct: 1062 --GHRGFTGLQGLPG-----PPGP----SGDQGASGPAGPSGPRGPPG--PVGPSGKDGA 1108
Query: 658 SSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPG 699
+ IPG P+G P + RSG PA PG+ PP PPG
Sbjct: 1109 NGIPG-----PIGPP--GPRGRSGETGPAGPPGNPGPPGPPG 1143
Score = 108 bits (271), Expect = 4e-23
Identities = 227/904 (25%), Positives = 282/904 (31%), Gaps = 194/904 (21%)
Query: 83 GGAGGGAPQ--PGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPA-- 138
G G PQ GP + Q G + G+ P G P P AP GE
Sbjct: 366 GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP---GPAGPQGAPGPAGEEGKR 422
Query: 139 GGRYEHPGLGALGTQQPPVAVPGGGGGPA--AVPEFNNYYG-SAAPASGGPGGRAGPCFD 195
G R E G+G P+ PG G P P + G AP GP G AGP
Sbjct: 423 GARGEPGGVG-------PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPK-G 474
Query: 196 QHGGQQSPGMGMMHSASAAAAGAPGSMDPL----------QNSHEGYPNSQ-CNHYPGYS 244
+G PG + A G PG P ++ G P Q PG
Sbjct: 475 ANGDPGRPGEPGLPGARGLT-GRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVM 533
Query: 245 RPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSS 304
G G G G G G G G G AA A AG G G G S
Sbjct: 534 GFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPS 593
Query: 305 AGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQL 364
G+ P G G PG G + A G + F G+ P Q
Sbjct: 594 GFQGLPGPPGPPGEGGK--PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA------QG 645
Query: 365 LTSPSPMMRSYGGSYPEYSS-PSAPP----PPPSQPQSQAAAAGAAAG-----------G 408
L P + + G P+ +S P+ PP PP Q A AG G
Sbjct: 646 LQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKG 705
Query: 409 QQAAAGMGLGKDMGAQYAAASPAWAAAQQRS----HPAMSPGTPGPTMGRSQGSPMDPMV 464
+ A G G+ + PA A ++ PA S G G R + P P
Sbjct: 706 PEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAG 765
Query: 465 MKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQ----Q 520
P G P ++ +Q G G PGPQ P G G P G+ P+
Sbjct: 766 FAGPP--GADGQPGAKGEQGEAGQKGDAGAPGPQG-PSGAPG--PQGPTGVTGPKGARGA 820
Query: 521 QMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP-PQAQYLPSQSQQRYQPQQDMSQEGYG 579
Q PP G G G + P + P PP P P + P ++ P + G
Sbjct: 821 QGPP--GATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ 878
Query: 580 TRSQPPLAPGKPNHED-------------------LNLIQQERPSSLPDLSGSIDDLPTG 620
+ PP G+P + + L Q P L G P+G
Sbjct: 879 GPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG-----PSG 933
Query: 621 TEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPG--GP-------------- 664
E A ASG G P + P P PG GP
Sbjct: 934 -EPGKQGAPGASGDRGPPGPVGPPGLT--GPAGEPGREGSPGADGPPGRDGAAGVKGDRG 990
Query: 665 ---------SPSPVGSPVGSN-------------QSRSGPISPASIPGSQMPPQPPGSQS 702
+P P GSP + Q GP PA G Q P P G +
Sbjct: 991 ETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKG 1050
Query: 703 ESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQ 762
E+ P ERG GP P P G A
Sbjct: 1051 EAGE---------PGERGLKGHRGFTGLQGLPGP----------PGPSGDQGA------- 1084
Query: 763 SNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHG-QGPSQPCG 821
SG GP GP+G PGP +G S + +G GP P G
Sbjct: 1085 ---SGPAGPS----GPRG-----------------PPGP-VGPSGKDGANGIPGPIGPPG 1119
Query: 822 AVPLGRMPSAGMQNRP-FPGNMSSMTPSSPGMSQQGGPGMGP----PMPTVNRKAQEAAA 876
P GR G P PG P PG+ G+GP P P +A +AA
Sbjct: 1120 --PRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAG 1177
Query: 877 AVMQ 880
+ Q
Sbjct: 1178 GLRQ 1181
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 124 bits (310), Expect = 1e-27
Identities = 255/1001 (25%), Positives = 325/1001 (32%), Gaps = 175/1001 (17%)
Query: 88 GAPQP----GPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYE 143
GAP P GP E + G S G PPGPP K GD+ +A G+P
Sbjct: 194 GAPGPQGFQGPPGEPGEPGA---SGPMGPRGPPGPP--GKNGDDGEA----GKP------ 238
Query: 144 HPGLGALGTQQPPVAVPGGG-GGPAAVPEFNNYYG-SAAPASGGPGGRAGPCFDQHGGQQ 201
G G + PP G G A +P + G S + G G AGP G
Sbjct: 239 ----GRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGP----KGEPG 290
Query: 202 SPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGG--GGGGGGGGG 259
SPG GAPG M P G P + RPGA G G G G
Sbjct: 291 SPGEN----------GAPGQMGP-----RGLPGER-------GRPGAPGPAGARGNDGAT 328
Query: 260 GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGG 319
G +G G G AG G A A G G G GS GV P G
Sbjct: 329 GAAGPPGPTGPAGPPG---------FPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPA 379
Query: 320 MMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYG--- 376
GP G A A G A G AG P P+ Q P + G
Sbjct: 380 GAAGPAGNPGADGQPGAKG--ANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPG 437
Query: 377 --GSYPEYSSPSAPPPPPSQ-PQSQAAAAG-AAAGGQQAAAGM-GLGKDMGAQYAAASPA 431
GS + + P P Q P A G A G+ G+ G + G + P
Sbjct: 438 APGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPG 497
Query: 432 WAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGS 491
PA G+PGP G P RP G+ SP P G
Sbjct: 498 ADGVAGPKGPAGERGSPGPA-----GPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGK 552
Query: 492 YGPPGPQRYPIGIQGR-----TPGA--MAG-MQYPQQQ----MPPQYGQQGVSGYCQQGQ 539
GPPG P G GR PGA AG M +P + P + G++GV G G
Sbjct: 553 TGPPG----PAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPG--PPGA 606
Query: 540 QPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLI 599
+ + P P+ + P +G + PP GKP
Sbjct: 607 VGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPG------- 659
Query: 600 QQERPSSL--PDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSN-----PAQSPFSP- 651
+Q P L P SG+ + E + +G + G N A +P +P
Sbjct: 660 EQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPG 719
Query: 652 -HASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQ---------MPPQP---P 698
+P L +PG + + P G ++ +GP PG PP P P
Sbjct: 720 SQGAPGLQGMPGERGAAGLPGPKG-DRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAP 778
Query: 699 GSQSESS-SHPA--LSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHA 755
G + ES S PA P +RG + GP PG +
Sbjct: 779 GDKGESGPSGPAGPTGARGAPGDRG---------EPGPPGPAGFAGPPGADGQPGAKGEP 829
Query: 756 GISSFQ-QSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSG----PGPGMGISANNQ 810
G + + + G GP GP GN P A SA G PG +
Sbjct: 830 GDAGAKGDAGPPGPAGP-AGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGP 888
Query: 811 MHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMT--PSSPG-MSQQGGPGMGPPMPTV 867
GP P G P G+ G + P P PG ++G PG P
Sbjct: 889 SGNAGPPGPPG--PAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAP 946
Query: 868 NRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQP-MNNSSSLMNTQAPPY 926
+ A Q + FPG+ P +P S + PP
Sbjct: 947 GTPGPQGIAGQRGVVGLPGQRGERGFPGL--------PGPSGEPGKQGPSGASGERGPPG 998
Query: 927 SMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPP 986
M P GLA PGES A+G P +K D + P
Sbjct: 999 PMGPP---------GLAG--PPGESGREGAPGAEGSPGRDGSPGAKG-DRGETGPAGPPG 1046
Query: 987 TPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSSP 1027
PG P P+ P+ S GD + + P P P P
Sbjct: 1047 APGAPGAPGPVGPAGKS-----GDRGE--TGPAGPAGPVGP 1080
Score = 114 bits (284), Expect = 1e-24
Identities = 257/1046 (24%), Positives = 321/1046 (30%), Gaps = 195/1046 (18%)
Query: 73 QHPISNNNSLGGAGGGAPQ--PGPDMEQPQHGGAKDSAAGGQADPPGPP----------- 119
Q P G +G P+ PGP + G A G+ PPGP
Sbjct: 202 QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGL 261
Query: 120 -----------LLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAA 168
L GD A PK GEP PG Q P +PG G P A
Sbjct: 262 PGMKGHRGFSGLDGAKGDAGPAGPK-GEPGS-----PGENGAPGQMGPRGLPGERGRPGA 315
Query: 169 VPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNS 228
A + GP G GP G PG A GA G P
Sbjct: 316 PGPAGARGNDGATGAAGPPGPTGPA----GPPGFPG----------AVGAKGEAGPQGPR 361
Query: 229 HEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAA 288
P G P G G G G G G G GA G A
Sbjct: 362 GSEGPQG----VRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGP 417
Query: 289 AAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFA 348
+ G GG G G+S G S G GP G + G A +R A
Sbjct: 418 SGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVG------VQGPPGPAGEEGKRGA 471
Query: 349 GQNQHPSGATPTLNQLLTSPSPMMRSYGGS--YPEYSSPSAPPPPPSQPQSQAAAAGAAA 406
P+G L P P R GS +P + P P + S A +
Sbjct: 472 RGEPGPTG--------LPGP-PGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGS 522
Query: 407 GGQQAAAG-MGLGKDMGAQYAAASPAWAAAQQRSHPAMS---PGTPGPTMGRSQGSPMDP 462
G+ G GL G + SP PA PG PGP R Q
Sbjct: 523 PGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAG---- 578
Query: 463 MVMKRPQLYGMGSNPHSQPQQSSPYP------------GGSYGPPGPQRYPIGIQG-RTP 509
VM P G P ++ P P G+ GPPGP P G +G + P
Sbjct: 579 -VMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAG-PAGERGEQGP 636
Query: 510 GAMAGMQ-YPQQQMPP----QYGQQGVSGYC-------QQGQQPYYS----QQPQPPHLP 553
G Q P PP + G+QGV G +G++ + Q P P P
Sbjct: 637 AGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGP 696
Query: 554 PQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQER-PSSLPDLSG 612
A P +G + P APG L + ER + LP G
Sbjct: 697 RGANGAP-------------GNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKG 743
Query: 613 SIDDL-PTGTEAT--------LSSAVSASGSTSSQGDQ-----SNPAQSPFSPHASPHLS 658
D P G + + L+ + G + GD+ S PA P +P
Sbjct: 744 DRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPA-GPTGARGAPGDR 802
Query: 659 SIPGGPSPSPVGSPVGSN--------------QSRSGPISPASIPGSQMPPQPPGSQSES 704
PG P P+ P G++ + +GP PA G PP P G+
Sbjct: 803 GEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAG---PPGPIGNVGAP 859
Query: 705 SSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSN 764
+ A + P GF R GP GPS + P PG AG
Sbjct: 860 GAKGARGSAGPPGATGFPGAAGR------VGP--PGPSGNAGP-PGPPGPAG-------- 902
Query: 765 SSGTYGPQMSQYGPQGNYSR--PPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGA 822
G GP+ + GP G PP G P+ PG A QG + G
Sbjct: 903 KEGGKGPR-GETGPAGRPGEVGPPGPPG-PAGEKGSPGADGPAGAPGTPGPQGIAGQRGV 960
Query: 823 VPL-GRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPG-MGPP--MPTVNRKAQEAAAAV 878
V L G+ G P P S ++G PG MGPP +E A
Sbjct: 961 VGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGA--- 1017
Query: 879 MQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAA 938
A + R GS G + P P P + PA +
Sbjct: 1018 --PGAEGSPGRDGSPGAKGDRGETGPAGPPGAP--------GAPGAPGPVGPAGKSGDRG 1067
Query: 939 SVGLADMMSP-GESKLPLPLKADG----KEEGTPQPESKSKDSYSSQGISQPPTPGNLPV 993
G A P G P G K E Q + K G+ PP P
Sbjct: 1068 ETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPG--S 1125
Query: 994 PSPMSPSSASISSFHGDESDSISSPG 1019
P PS AS + S +PG
Sbjct: 1126 PGEQGPSGASGPAGPRGPPGSAGAPG 1151
Score = 107 bits (266), Expect = 2e-22
Identities = 182/672 (27%), Positives = 217/672 (32%), Gaps = 106/672 (15%)
Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPP-LLSKPGDEDDAPPKMGEP--AGG 140
GA G GP E+ + G A G P GPP KPG E P +G P +G
Sbjct: 617 GAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPG-EQGVPGDLGAPGPSGA 675
Query: 141 RYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQ 200
R E G G Q PP P G G P + G A A G PG + P G Q
Sbjct: 676 RGERGFPGERGVQGPPG--PAGPRGANGAPGNDGAKGDAG-APGAPGSQGAP-----GLQ 727
Query: 201 QSPGMGMMHSASAAAAGAPGSM----DPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGG 256
PG AAG PG D +G P + G + P G G
Sbjct: 728 GMPG-------ERGAAGLPGPKGDRGDAGPKGADGSPGK--DGVRGLTGPIGPPGPAGAP 778
Query: 257 GGGGGSGGGGGGGGAGAGGAGAGAVA------AAAAAAAAAAGGGGGGGYGGSSAGYGVL 310
G G SG G G GA GA A A A G G G G + G
Sbjct: 779 GDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDA 838
Query: 311 SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGAT--PTLNQLLTSP 368
P G GP G A +K A GSA P GAT P + P
Sbjct: 839 GPPGPAGPAGPPGPIGNVGAPGAKGARGSAG------------PPGATGFPGAAGRVGPP 886
Query: 369 SPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAA 428
P S +A PP P P + G G+ AG +
Sbjct: 887 GP-------------SGNAGPPGPPGPAGKEGGKGPR--GETGPAG------RPGEVGPP 925
Query: 429 SPAWAAAQQRS----HPAMSPGTPGPTMGRSQ----GSPMDPMVMKRPQLYGMGSNPHSQ 480
P A ++ S PA +PGTPGP Q G P P L G P Q
Sbjct: 926 GPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQ 985
Query: 481 PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYP-QQQMPPQYGQQGVSGYCQQGQ 539
+ G GPPGP P G+ G PG P + P + G G G
Sbjct: 986 GPSGA---SGERGPPGPMG-PPGLAG-PPGESGREGAPGAEGSPGRDGSPGAKG------ 1034
Query: 540 QPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQP--PLAPGKPNHEDLN 597
+ P PP A P P + G + P P P P
Sbjct: 1035 ----DRGETGPAGPPGAPGAPGAP----GPVGPAGKSGDRGETGPAGPAGPVGPVGA-RG 1085
Query: 598 LIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQS-NPAQSPFSPHASPH 656
+ P +G D S G S G+Q + A P P P
Sbjct: 1086 PAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPG 1145
Query: 657 LSSIPGGPS----PSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQ 712
+ PG P P+G P + R+G P PG PP PPG S L Q
Sbjct: 1146 SAGAPGKDGLNGLPGPIGPP--GPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQ 1203
Query: 713 SPMPQERGFMAG 724
PQE+ G
Sbjct: 1204 P--PQEKAHDGG 1213
Score = 73.2 bits (178), Expect = 3e-12
Identities = 266/1174 (22%), Positives = 362/1174 (30%), Gaps = 231/1174 (19%)
Query: 373 RSYGG-SYPEYSSPSAP---PPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAA 428
+S GG S P PS P P PP P Q G+ A+G MG +
Sbjct: 170 KSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASG-----PMGPR---G 221
Query: 429 SPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYP 488
P A PG PG +G P P G+ +
Sbjct: 222 PPGPPGKNGDDGEAGKPGRPG-----ERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGA 276
Query: 489 GGSYGPPGPQRYPIGIQGR--TPGAMAGMQYPQQQ----MPPQYGQQGVSGYCQQGQQPY 542
G GP GP+ P G G PG M P ++ P G +G G P
Sbjct: 277 KGDAGPAGPKGEP-GSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPG 335
Query: 543 YSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEG-YGTRSQPPLAPGKPNHEDLNLIQQ 601
+ PP P ++ PQ EG G R + PG P
Sbjct: 336 PTGPAGPPGFPGAV-----GAKGEAGPQGPRGSEGPQGVRGE----PGPPG--------- 377
Query: 602 ERPSSLPDLSGS--IDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSS 659
P+ +G+ D P A + ++ + S P Q P P S
Sbjct: 378 --PAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGP-QGPGGPPGPKGNSG 434
Query: 660 IPGGP----------SPSPVG-----SPVGSNQSRS--GPISPASIPGSQMPPQPPGSQS 702
PG P P PVG P G R G P +PG PPG +
Sbjct: 435 EPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPG------PPGERG 488
Query: 703 ESSSHPALSQSPMPQERGF-----MAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGI 757
P RGF +AG + P + P GP SP + G AG+
Sbjct: 489 G------------PGSRGFPGADGVAG-PKGPAGERGSPGPAGPKGSPGEA-GRPGEAGL 534
Query: 758 SSFQ-QSNSSGTYGP--QMSQYGPQGNYSRPPAYSGVPSASYSG-----PGPGMGISANN 809
+ + S G+ GP + GP G R P G P A PGP
Sbjct: 535 PGAKGLTGSPGSPGPDGKTGPPGPAGQDGR-PGPPGPPGARGQAGVMGFPGPKGAAGEPG 593
Query: 810 QMHGQGPSQPCGAV-PLGRMPSAGMQNRPFP----GNMSSMTPS-SPGMSQQGGPGMGPP 863
+ +G P GAV P G+ AG Q P P G P+ SPG QG PG P
Sbjct: 594 KAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGF--QGLPGPAGP 651
Query: 864 MPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQA 923
+ ++ + A S + FPG + G+ P + P + + N A
Sbjct: 652 PGEAGKPGEQGVPGDLGAPGPSGARGERGFPG--ERGVQGPPGP-AGPRGANGAPGNDGA 708
Query: 924 PPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGIS 983
+ AP S A GL M PGE G P P+ D+
Sbjct: 709 KGDAGAPGAPGSQGAP-GLQGM--PGER----------GAAGLPGPKGDRGDAGPKGADG 755
Query: 984 QPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSSPKSSSSTTTGEKITKVY 1043
P G + P+ P + GD+ + S P P P+ + +
Sbjct: 756 SPGKDGVRGLTGPIGPPGP--AGAPGDKGE--SGPSGPAGPTGARGAPG----------- 800
Query: 1044 ELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKK 1103
+RG P PA P G Q +
Sbjct: 801 --------------------DRGEPGPPGPAGFAGP------------PGADGQPGAKGE 828
Query: 1104 WRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPP 1163
+ + G A + I + A K RG PP +TG ++ PP
Sbjct: 829 PGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPG--ATGFPGAAGRVGPP 886
Query: 1164 SPANSGSLQGPQTPQS-------TGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTI 1216
P+ + GP P G A PG++ PP P P G +
Sbjct: 887 GPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGP---------PGPAGEKGSP 937
Query: 1217 SVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEP 1276
P + P P QG++ + +P + + F G+ PG S
Sbjct: 938 GADGP-------------AGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGL---PGPSGE 981
Query: 1277 FMTQGQMPNSSMQDMYN-QSPSGAMSNLGMGQRQQFPYG-ASYDRRHEPYGQQYPGQGPP 1334
QG S + P G G R+ P S R P + G+ P
Sbjct: 982 PGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGP 1041
Query: 1335 SGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYS 1394
+G P G P P K G GP + + Q G +
Sbjct: 1042 AGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGE 1101
Query: 1395 GPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMG--GPLQSSSSEGPQQNMWAA--- 1449
D R I+G + +QGP PP G GP +S GP+ +A
Sbjct: 1102 QGD-RGIKGHRGF----SGLQGPPG------PPGSPGEQGPSGASGPAGPRGPPGSAGAP 1150
Query: 1450 ----RNDMPYPY-----QNRQGPGGPTQAPPYPG 1474
N +P P + R G GP P PG
Sbjct: 1151 GKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPG 1184
Score = 57.8 bits (138), Expect = 1e-07
Identities = 147/619 (23%), Positives = 199/619 (32%), Gaps = 104/619 (16%)
Query: 482 QQSSPYPGGSYGPPGP--------QRYPIGIQGRTPGAMA-----GMQYPQ--QQMPPQY 526
Q P P G GPPGP + G ++ G ++ G P+ P
Sbjct: 137 QPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAP 196
Query: 527 GQQGVSGYCQQGQQPYYS--QQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQP 584
G QG G + +P S P+ P PP ++ + +P + G R P
Sbjct: 197 GPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLP 256
Query: 585 PLA--PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSS-----AVSASGSTSS 637
A PG H S L G D P G + S A G
Sbjct: 257 GTAGLPGMKGHRGF--------SGLDGAKG--DAGPAGPKGEPGSPGENGAPGQMGPRGL 306
Query: 638 QGDQSNP-AQSPFSPHASPHLSSIPGGPSPS-PVGSP-----VGSN-----QSRSGPISP 685
G++ P A P + + G P P+ P G P VG+ Q G P
Sbjct: 307 PGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGP 366
Query: 686 ASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGF--MAGTQRNP-QMAQYGPQQTGPS 742
+ G PP P G+ + + A Q G +AG P GPQ GP
Sbjct: 367 QGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQ--GPG 424
Query: 743 MSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQ--YGPQGNYSR-----PPAYSGVPSAS 795
P P S + + G GP Q GP G + P +G+P
Sbjct: 425 GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPP 484
Query: 796 YSGPGPG-MGISANNQMHG-QGPSQPCGAV-PLGRMPSAGMQNRP----FPGNMS-SMTP 847
GPG G + + G +GP+ G+ P G S G RP PG + +P
Sbjct: 485 GERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSP 544
Query: 848 SSPGMSQQGGP--------GMGPPMPTVNRKAQEAAAAVM------QAAANSAQSRQGSF 893
SPG + GP GPP P R A VM AA ++ +
Sbjct: 545 GSPGPDGKTGPPGPAGQDGRPGPPGPPGAR----GQAGVMGFPGPKGAAGEPGKAGERGV 600
Query: 894 PGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKL 953
PG P + Q PP PA G SPG L
Sbjct: 601 PG----------PPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAG-----SPGFQGL 645
Query: 954 PLPLKADGK-----EEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFH 1008
P P G+ E+G P S + P G P P P A+ + +
Sbjct: 646 PGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGN 705
Query: 1009 GDESDSISSPGWPKTPSSP 1027
+PG P + +P
Sbjct: 706 DGAKGDAGAPGAPGSQGAP 724
Score = 41.6 bits (96), Expect = 0.009
Identities = 87/375 (23%), Positives = 116/375 (30%), Gaps = 79/375 (21%)
Query: 661 PGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG 720
P GP P G P R G +PG PP PPG P L + PQ
Sbjct: 119 PRGPR-GPAGPP-----GRDGIPGQPGLPGPPGPPGPPGP-------PGLGGNFAPQ--- 162
Query: 721 FMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQG 780
YG + P P G S G GP + GPQG
Sbjct: 163 -----------LSYGYDEKSTGGISVPGPMG----------PSGPRGLPGPPGAP-GPQG 200
Query: 781 NYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPG 840
+ PP G P A SGP GP P G P G+ G + PG
Sbjct: 201 -FQGPPGEPGEPGA--SGP--------------MGPRGPPG--PPGKNGDDGEAGK--PG 239
Query: 841 NMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGM-NQS 899
P P QG G+ K + + A ++ + PG ++
Sbjct: 240 RPGERGPPGP----QGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGEN 295
Query: 900 GLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLP--LPL 957
G P P + P + PA + + G A P P P
Sbjct: 296 GAPGQMGPRGLP--------GERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPG 347
Query: 958 KADGKEEGTPQPESKSKDSYSSQGISQPPTPGNL--PVPSPMSPSSASISSFHGDESDSI 1015
K E PQ S+ +G PP P P +P + +G +
Sbjct: 348 AVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIA- 406
Query: 1016 SSPGWP--KTPSSPK 1028
+PG+P + PS P+
Sbjct: 407 GAPGFPGARGPSGPQ 421
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 121 bits (304), Expect = 7e-27
Identities = 260/1067 (24%), Positives = 344/1067 (32%), Gaps = 193/1067 (18%)
Query: 71 QQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADP------------PGP 118
Q+ P + +G G PQ GP EQ G D G P PGP
Sbjct: 105 QKGEPGDIKDIVGPKGPPGPQ-GPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGP 163
Query: 119 PLLSKPGDEDDAPPKMG-----EPAGGRYEHPGLGALGTQQPPVAV--PGGGGGPAAVPE 171
P PG PP +G + AGG E G LG Q P+ P G GPA P
Sbjct: 164 P--GPPGPP--GPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 219
Query: 172 FNNYYGSAA----PASGGPGGRAGPCF-------DQHGGQQSPGMGMMHSASAAAAGAPG 220
+ G+ P GP G GP D G+ A G PG
Sbjct: 220 PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPG 279
Query: 221 SMD-PLQNSHEGYPNSQC-------------------NHYPG----YSRPGAGG--GGGG 254
+ P H GYP N PG PG G G G
Sbjct: 280 TPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAG 339
Query: 255 GGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPR 314
G G G G G G G G A A AG G G G+ G +P
Sbjct: 340 AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG 399
Query: 315 QQG-GGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQN--QHPSGATPTLNQLLTSPSPM 371
G G PG G +A G F G P GAT L + P
Sbjct: 400 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 459
Query: 372 MRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAA--GGQQAAAGMGLGKDMGAQYAAAS 429
+ + G P P+ PQ AG G + G+G G + A +
Sbjct: 460 IAGFKGEQGPKGEPG-----PAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGN 514
Query: 430 PAWAAAQQRSHPAMSPGTPGPT-MGRSQGSPMDPMVMKRPQLYGM----GSNPHSQPQ-- 482
+ + P +PG GP+ + +G+ DP P L G G + PQ
Sbjct: 515 RGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGK 574
Query: 483 ---QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQ--QQMPPQYGQQGVSGYCQQ 537
+P G GPPGPQ G +G+ PG M G P+ P + G++G+ G
Sbjct: 575 VGPSGAPGEDGRPGPPGPQ----GARGQ-PGVM-GFPGPKGANGEPGKAGEKGLPG---- 624
Query: 538 GQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLN 597
P + LP + + G R + APG + L
Sbjct: 625 ---------------APGLRGLPGKDGETGAAGPPGPAGPAGERGEQG-APGPSGFQGL- 667
Query: 598 LIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNP-AQSPFSPHASPH 656
P P G D EA V G G++ +P AQ P P
Sbjct: 668 ----PGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP- 722
Query: 657 LSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMP 716
PG P + SGP P PG+Q PPG Q A +
Sbjct: 723 --GTPGTDGP----------KGASGPAGP---PGAQ---GPPGLQGMPGERGAAGIAGPK 764
Query: 717 QERGFMAGTQRNPQMA---QYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGP-- 771
+RG + ++ P+ A G TGP P P+ + + S+G G
Sbjct: 765 GDRGDVG--EKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPG 822
Query: 772 QMSQYGPQG--NYSRPPAYSGVPSAS-----------YSGPGPGMGISANNQMHGQGPSQ 818
+ + GP G ++ PP G P A PGP GP
Sbjct: 823 ERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGP------QGPSGAPGPQG 876
Query: 819 PCGAVPLGRMPSAGMQNRP----FPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEA 874
P G G + G Q P FPG + P PG + GP GPP P+
Sbjct: 877 PTGVT--GPKGARGAQGPPGATGFPGAAGRVGP--PGSNGNPGPP-GPPGPS-------G 924
Query: 875 AAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVN 934
A +S + PG+ G +P ++ S + PP P +
Sbjct: 925 KDGPKGARGDSGPPGRAGEPGLQ--GPAGPPGEKGEPGDDGPS--GAEGPP---GPQGLA 977
Query: 935 SSAASVGLADMMSP-GESKLPLPLKADGKEEGTP--QPESKSKDSYSSQGISQPP-TPGN 990
VGL G LP P GK+ G P + G++ P PG
Sbjct: 978 GQRGIVGLPGQRGERGFPGLPGPSGEPGKQ-GAPGASGDRGPPGPVGPPGLTGPAGEPGR 1036
Query: 991 LPVPSPMSP----SSASISSFHGDESDSISSPGWPKTPSSPKSSSST 1033
P P +A + G E+ ++ +PG P P SP + T
Sbjct: 1037 EGSPGADGPPGRDGAAGVKGDRG-ETGAVGAPGAPGPPGSPGPAGPT 1082
Score = 112 bits (281), Expect = 3e-24
Identities = 180/642 (28%), Positives = 213/642 (33%), Gaps = 94/642 (14%)
Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS-KPGDEDDAPPKMGEPA--GG 140
GA G GP E+ + G S G PPGPP KPGD+ P + G P G
Sbjct: 639 GAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQG-VPGEAGAPGLVGP 697
Query: 141 RYEHPGLGALGTQQPPVAVPGGGG--GPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHG 198
R E G G+ PG G GP +P P + GP G +GP G
Sbjct: 698 RGERGFPGERGS-------PGAQGLQGPRGLP--------GTPGTDGPKGASGPA-GPPG 741
Query: 199 GQQSPGMGMMHSASAAA--AGAPGSM-DPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGG 255
Q PG+ M AA AG G D + EG P G + P G G
Sbjct: 742 AQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGR--GLTGPIGPPGPAGA 799
Query: 256 GGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQ 315
G G G G G AGA GA A AG G G G+ G
Sbjct: 800 NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD 859
Query: 316 QGGGMMMGPGGG-GAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRS 374
G GP G G + A G Q G P A
Sbjct: 860 AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAA----------------- 902
Query: 375 YGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAA-GGQQAAAGMGLGKDMGAQYAAASPAWA 433
G P S+ + PP P P + GA G AG + G Q A P
Sbjct: 903 -GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAG-----EPGLQGPAGPPGEK 956
Query: 434 AAQQRSHPAMSPGTPGPTMGRSQ----GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPG 489
P+ + G PGP Q G P P L G P +Q +P
Sbjct: 957 GEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPG---KQGAPGAS 1013
Query: 490 GSYGPPGPQRYPIGIQGRTPGAMAGMQ-YPQQQMPP-QYGQQGVSGYCQQGQQPYYSQQP 547
G GPPGP P G+ G P G + P PP + G GV G + P
Sbjct: 1014 GDRGPPGPVGPP-GLTG--PAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAP 1070
Query: 548 QPPHLPPQAQYLPSQSQQ-RYQPQQDMSQEG-YGTRS-QPPLAP-------GKPNHEDLN 597
PP P A Q + Q M G G R Q P P G+P L
Sbjct: 1071 GPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLK 1130
Query: 598 LIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHL 657
+ L L G P G S ASG G + P P P
Sbjct: 1131 --GHRGFTGLQGLPG-----PPGP----SGDQGASGPAGPSGPRGPPG--PVGPSGKDGA 1177
Query: 658 SSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPG 699
+ IPG P+G P + RSG PA PG+ PP PPG
Sbjct: 1178 NGIPG-----PIGPP--GPRGRSGETGPAGPPGNPGPPGPPG 1212
Score = 108 bits (271), Expect = 4e-23
Identities = 227/904 (25%), Positives = 282/904 (31%), Gaps = 194/904 (21%)
Query: 83 GGAGGGAPQ--PGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPA-- 138
G G PQ GP + Q G + G+ P G P P AP GE
Sbjct: 435 GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP---GPAGPQGAPGPAGEEGKR 491
Query: 139 GGRYEHPGLGALGTQQPPVAVPGGGGGPA--AVPEFNNYYG-SAAPASGGPGGRAGPCFD 195
G R E G+G P+ PG G P P + G AP GP G AGP
Sbjct: 492 GARGEPGGVG-------PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPK-G 543
Query: 196 QHGGQQSPGMGMMHSASAAAAGAPGSMDPL----------QNSHEGYPNSQ-CNHYPGYS 244
+G PG + A G PG P ++ G P Q PG
Sbjct: 544 ANGDPGRPGEPGLPGARGLT-GRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVM 602
Query: 245 RPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSS 304
G G G G G G G G G AA A AG G G G S
Sbjct: 603 GFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPS 662
Query: 305 AGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQL 364
G+ P G G PG G + A G + F G+ P Q
Sbjct: 663 GFQGLPGPPGPPGEGGK--PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA------QG 714
Query: 365 LTSPSPMMRSYGGSYPEYSS-PSAPP----PPPSQPQSQAAAAGAAAG-----------G 408
L P + + G P+ +S P+ PP PP Q A AG G
Sbjct: 715 LQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKG 774
Query: 409 QQAAAGMGLGKDMGAQYAAASPAWAAAQQRS----HPAMSPGTPGPTMGRSQGSPMDPMV 464
+ A G G+ + PA A ++ PA S G G R + P P
Sbjct: 775 PEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAG 834
Query: 465 MKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQ----Q 520
P G P ++ +Q G G PGPQ P G G P G+ P+
Sbjct: 835 FAGPP--GADGQPGAKGEQGEAGQKGDAGAPGPQG-PSGAPG--PQGPTGVTGPKGARGA 889
Query: 521 QMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP-PQAQYLPSQSQQRYQPQQDMSQEGYG 579
Q PP G G G + P + P PP P P + P ++ P + G
Sbjct: 890 QGPP--GATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ 947
Query: 580 TRSQPPLAPGKPNHED-------------------LNLIQQERPSSLPDLSGSIDDLPTG 620
+ PP G+P + + L Q P L G P+G
Sbjct: 948 GPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG-----PSG 1002
Query: 621 TEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPG--GP-------------- 664
E A ASG G P + P P PG GP
Sbjct: 1003 -EPGKQGAPGASGDRGPPGPVGPPGLT--GPAGEPGREGSPGADGPPGRDGAAGVKGDRG 1059
Query: 665 ---------SPSPVGSPVGSN-------------QSRSGPISPASIPGSQMPPQPPGSQS 702
+P P GSP + Q GP PA G Q P P G +
Sbjct: 1060 ETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKG 1119
Query: 703 ESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQ 762
E+ P ERG GP P P G A
Sbjct: 1120 EAGE---------PGERGLKGHRGFTGLQGLPGP----------PGPSGDQGA------- 1153
Query: 763 SNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHG-QGPSQPCG 821
SG GP GP+G PGP +G S + +G GP P G
Sbjct: 1154 ---SGPAGPS----GPRG-----------------PPGP-VGPSGKDGANGIPGPIGPPG 1188
Query: 822 AVPLGRMPSAGMQNRP-FPGNMSSMTPSSPGMSQQGGPGMGP----PMPTVNRKAQEAAA 876
P GR G P PG P PG+ G+GP P P +A +AA
Sbjct: 1189 --PRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAG 1246
Query: 877 AVMQ 880
+ Q
Sbjct: 1247 GLRQ 1250
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 121 bits (303), Expect = 9e-27
Identities = 257/1043 (24%), Positives = 333/1043 (31%), Gaps = 149/1043 (14%)
Query: 83 GGAGGGAPQPGPDMEQPQHGGAKDSAAG-----GQADPPGPPLLSKPGDEDDAPPKMGEP 137
G AG P P P KD +G G+ PGPP + P P G
Sbjct: 207 GQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHR 266
Query: 138 A--GGRYEHPGLGALGTQQPPVAVPGGGG-----GPAAVPEFNNYYG--SAAPASGGPGG 188
G E GA G + +PG G GP P G AA A G G
Sbjct: 267 GFDGRNGEKGETGAPGLKGEN-GLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGA 325
Query: 189 RAGPCFDQHGGQQSPGMGMMHSASAAA-----AGAPGSMDPLQNSHEGYPNSQCNHYPGY 243
R Q G PG + A AG+PGS E P
Sbjct: 326 RGSD--GQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPP 383
Query: 244 SRPGAGGGGGGGGGGG-----GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGG 298
PG G GG G G G G G G G GA A G G
Sbjct: 384 GPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEP 443
Query: 299 GYGGSSAGYGVLSSPRQQG-GGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGA 357
G G G+ P +G G PG GA L AA A GF+ AG N P
Sbjct: 444 GPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEK 503
Query: 358 TPTLNQLLTSPS-----------------PMMRSYGGSYPEYSSPSAPPPPPSQPQSQAA 400
P + P+ P MR GS S P PP SQ +S
Sbjct: 504 GPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRP 563
Query: 401 AAGAAAGGQQAAAGMGL----------GKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGP 450
+G + MG GK+ G + P ++ G PGP
Sbjct: 564 GPPGPSGPRGQPGVMGFPGPKGNDGAPGKN-GERGGPGGPGPQGPPGKNGETGPQGPPGP 622
Query: 451 T-MGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGP-----------Q 498
T G +G P L G G P + P P G G PG +
Sbjct: 623 TGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGE 682
Query: 499 RYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQY 558
R P G+ G PG G P G +G G P + P +P +
Sbjct: 683 RGPPGLAG-APGLRGGAGPP--------GPEGGKGAAGPPGPPGAAGTPGLQGMPGERGG 733
Query: 559 LPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLP 618
L S P+ D + G P A G P + P P +G D
Sbjct: 734 LGSPG-----PKGDKGEPG------GPGADGVPGKDGPR--GPTGPIGPPGPAGQPGDKG 780
Query: 619 TGTEATLSSAVSASGSTSSQGDQS--NPAQSPFSPHAS--------------------PH 656
G L GS +G+ PA P +P + P
Sbjct: 781 EGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPG 840
Query: 657 LSSIPGGPSPSPVGSPVGSNQSRSGPISP--ASIPGSQMPPQPPGSQSESSSHPALSQSP 714
++ PGG P+ P G R P P A PG++ P PPGS P S SP
Sbjct: 841 VAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGP-PGPSGSP 899
Query: 715 MPQERGFMAGTQRNP----------QMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQ-S 763
AG P Q G + + + P +PG AGI+ + +
Sbjct: 900 GKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLA 959
Query: 764 NSSGTYGPQMSQYGPQG--NYSRPPAYSGVPSASYSGPGP-GM-GISANNQMHGQGPSQP 819
G GP+ S GPQG S P +G+ S PGP G+ G++ G+ +
Sbjct: 960 GPPGMPGPRGSP-GPQGVKGESGKPGANGL-SGERGPPGPQGLPGLAGTAGEPGRDGNPG 1017
Query: 820 CGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVM 879
+P GR S G + N S P +PG GP +GP + +R E+ A
Sbjct: 1018 SDGLP-GRDGSPGGKGDRGE-NGSPGAPGAPGHPGPPGP-VGPAGKSGDRG--ESGPAGP 1072
Query: 880 QAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAAS 939
A A SR P + + + + P S PA + S
Sbjct: 1073 AGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGS 1132
Query: 940 VGLADMMSP----------GESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPG 989
G A P G S P P+ G + E S+ S G PP P
Sbjct: 1133 PGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGN--RGERGSEGSPGHPGQPGPPGPP 1190
Query: 990 NLPVPSPMSPSSASISSFHGDES 1012
P P +A+I+ G+++
Sbjct: 1191 GAPGPCCGGVGAAAIAGIGGEKA 1213
Score = 115 bits (289), Expect = 4e-25
Identities = 254/1057 (24%), Positives = 325/1057 (30%), Gaps = 177/1057 (16%)
Query: 65 QQQQQQQQQHPISNNNSLGGAGG---GAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLL 121
Q Q + + + ++GG G A PGP G + G PPG P
Sbjct: 149 QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQ 208
Query: 122 SKPGDEDDAPPKMGE--PAG--GRYEHPGL-GALGTQQPPVAVPGGGGGPAAVPEFNNYY 176
+ P P +G PAG G PG G G PP G GPA +P F
Sbjct: 209 AGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPP-----GIKGPAGIPGFPGMK 263
Query: 177 GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQ 236
G G GR G + G +PG+ + GAPG M P G P +
Sbjct: 264 GHR-----GFDGRNG----EKGETGAPGL-KGENGLPGENGAPGPMGP-----RGAPGER 308
Query: 237 CNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGG 296
RPG G G G G G G G A + A G G
Sbjct: 309 -------GRPGLPGAAGA-------RGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVG 354
Query: 297 GGGYGGSSAGYGVLSSPRQQGGGMMMGPGG--------GGAASLSKAAAGSAAG-----G 343
G GS+ G P QG GP G GG + A A G G
Sbjct: 355 PAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARG 414
Query: 344 FQRFAGQNQHP----SGATPTLNQLLTSPSPM-------MRSYGGSYPEYSSPSAPPPPP 392
AG N P P N P P + G+ E +P P
Sbjct: 415 PPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPG 474
Query: 393 SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTP-GPT 451
+ AA A G + A G+ + G +P A + + G P GP
Sbjct: 475 ANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPG 534
Query: 452 MGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGP---PGPQRYP-----IG 503
M GSP P +P P SQ + P P G GP PG +P G
Sbjct: 535 MRGMPGSPGGPGSDGKP------GPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDG 588
Query: 504 IQGRTPGAMAGMQYPQQQMPP----QYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYL 559
G+ G G P Q PP + G QG G G + P P L Q L
Sbjct: 589 APGKN-GERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGL----QGL 643
Query: 560 PSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHE-DLNLIQQERPSSL---PDLSGSID 615
P P + + G APG P + D + P L P L G
Sbjct: 644 PGTG----GPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAG 699
Query: 616 DLPTGTEATLSSA-----------------------VSASGSTSSQGDQSNPAQSPFSPH 652
P G E +A + + G +G+ P
Sbjct: 700 --PPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGK 757
Query: 653 ASPHLSSIPGGPSPSPVGSP----VGSNQSRSGPISPASIPGSQ---MPPQP---PGSQS 702
P + P GP P P G P G G P PG + PP P PG+
Sbjct: 758 DGPRGPTGPIGP-PGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPG 816
Query: 703 ESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHP--------SPGGQMH 754
++ + P E+G + P P +GP+ P P SPGG
Sbjct: 817 QNGEPGGKGERGAPGEKG-----EGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGA 871
Query: 755 AGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQ 814
AG + G GP G GN PP SG P PGP A
Sbjct: 872 AGF-----PGARGLPGPP----GSNGN-PGPPGPSGSPGKD-GPPGPAGNTGAPGSPGVS 920
Query: 815 GPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEA 874
GP G G S G Q P + + G PGM P P + Q
Sbjct: 921 GPKGDAGQP--GEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGM--PGPRGSPGPQGV 976
Query: 875 AAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMN-NSSSLMNTQAPPYSMAPAMV 933
+ AN +G GL ++ + N S L P
Sbjct: 977 KGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGE 1036
Query: 934 NSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTP-GNLP 992
N S + G +PG P P+ GK S + G + P P G+
Sbjct: 1037 NGSPGAPG-----APGHPGPPGPVGPAGK--------SGDRGESGPAGPAGAPGPAGSRG 1083
Query: 993 VPSPMSPSSASISSFHGDESDSISSPGWPKTPSSPKS 1029
P P P + + G+P P +P S
Sbjct: 1084 APGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGS 1120
Score = 84.3 bits (207), Expect = 1e-15
Identities = 217/928 (23%), Positives = 274/928 (29%), Gaps = 195/928 (21%)
Query: 160 PGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAP 219
P G GP +P N G P G G GP PG+ + P
Sbjct: 107 PKGDPGPPGIPGRNGDPG--IPGQPGSPGSPGP----------PGI------CESCPTGP 148
Query: 220 GSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAG 279
+ P +S++ GY P G G G G G G G G G
Sbjct: 149 QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQ 208
Query: 280 AVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGS 339
A + A G G G G S PG G L
Sbjct: 209 AGPSGPPGPPGAIGPSGPAGKDGESG-----------------RPGRPGERGLPGPPGIK 251
Query: 340 AAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPP---PPSQPQ 396
G F G H G + + +P ++ G E +P P P + +
Sbjct: 252 GPAGIPGFPGMKGH-RGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGR 310
Query: 397 SQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGT--------- 447
A A G A G G A P A+ PA SPG+
Sbjct: 311 PGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGE 370
Query: 448 PGPT-MGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPG--GSYGPPGPQRYPIGI 504
PGP +QG P P + P G P PG G+ GPPG P G
Sbjct: 371 PGPQGHAGAQGPPGPPGINGSP-----GGKGEMGPAGIPGAPGLMGARGPPG----PAGA 421
Query: 505 QGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQ 564
G PG G P G+ G G +P P +A +P
Sbjct: 422 NG-APGLRGGAGEP--------GKNGAKG------------EPGPRGERGEAG-IPGVPG 459
Query: 565 QRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEAT 624
+ + +D S PG+P L ER P G P G
Sbjct: 460 AKGEDGKDGS-------------PGEPGANGLPGAAGER--GAPGFRG-----PAGPN-- 497
Query: 625 LSSAVSASGSTSSQGDQSNPAQS-PFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPI 683
G G++ P + P P +PGGP R P
Sbjct: 498 -----GIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPG------------MRGMPG 540
Query: 684 SPASIPGSQMPPQPPGSQSESS-----------SHPALSQSPMPQ----------ERGFM 722
SP PGS P PPGSQ ES P + P P+ ERG
Sbjct: 541 SPGG-PGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGP 599
Query: 723 AGTQRNPQMAQYGPQQTGPSMSPHPS-PGGQM----HAGISSFQQSNSSGTYGP-----Q 772
G PQ +TGP P P+ PGG G Q GT GP +
Sbjct: 600 GGP--GPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQ--GLPGTGGPPGENGK 655
Query: 773 MSQYGPQGNYSRPPAYSGVPSASYSGP-GPGMGISANNQMHGQGPSQPCGAV-------P 824
+ GP+G+ P A G A G GP A G GP P G P
Sbjct: 656 PGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGP 715
Query: 825 LGRMPSAGMQNRPFP-GNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAA 883
G + G+Q P G + S P + GGPG + A
Sbjct: 716 PGAAGTPGLQGMPGERGGLGSPGPKG-DKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAG 774
Query: 884 NSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLA 943
+G P GL + P P T P + P + G
Sbjct: 775 QPGDKGEGGAP-----GLPGIAGPRGSPGERG----ETGPPGPAGFPGAPGQNGEPGGKG 825
Query: 944 DMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVP--SPMSPSS 1001
+ +PGE K +G G P S G + PP P + SP P +
Sbjct: 826 ERGAPGE-------KGEGGPPGVAGPPGGS-------GPAGPPGPQGVKGERGSPGGPGA 871
Query: 1002 ASISSFHG--DESDSISSPGWPKTPSSP 1027
A G S +PG P SP
Sbjct: 872 AGFPGARGLPGPPGSNGNPGPPGPSGSP 899
Score = 84.3 bits (207), Expect = 1e-15
Identities = 132/499 (26%), Positives = 162/499 (32%), Gaps = 77/499 (15%)
Query: 84 GAGGGAPQPGPDMEQ-----PQHGGAKDSAAG-GQADPPGPPLLSKPGDEDDAPPKMGEP 137
G G A QPG E P G + S G+ PPGP PG AP + GEP
Sbjct: 768 GPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPA--GFPG----APGQNGEP 821
Query: 138 AGGRYEHPGLGALGTQQPP-VAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQ 196
GG+ E G G PP VA P GG GPA P G G PGG F
Sbjct: 822 -GGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGER----GSPGGPGAAGFPG 876
Query: 197 HGGQQSPGMGMMHSASAAAAGAPGSMDPLQNS-HEGYPNSQCNHYPGYSRPGAGGGGGGG 255
G P + +G+PG P + + G P S PG S P G G
Sbjct: 877 ARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGS-----PGVSGPKGDAGQPGE 931
Query: 256 GGGGGGSGGGGGGGGAG-AGGAGAGAVAAAAAAAAAAAGGG-----GGGGYGGSSAGYGV 309
G G G G G G AG GA +A G G G G++ G
Sbjct: 932 KGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGE 991
Query: 310 LSSPRQQGGGMMMG----------PGGGGAASLSKAAAGSA---AGGFQRFAGQNQHPSG 356
P QG + G PG G + G G G HP
Sbjct: 992 RGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGP 1051
Query: 357 ATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQ---PQSQAAAAGAAAGGQQAAA 413
P P+ G S P + P+ P P P Q G++ AA
Sbjct: 1052 PGPV------GPAGKSGDRGESGP--AGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAA 1103
Query: 414 GMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRS-----QGSPMDPMVMKRP 468
G+ + A A QQ + + P P +G S G+ P + P
Sbjct: 1104 GIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPP 1163
Query: 469 QLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQ 528
G N + + SP G GPPGP P G A
Sbjct: 1164 ---GPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIA-------------- 1206
Query: 529 QGVSGYCQQGQQPYYSQQP 547
G+ G G PYY +P
Sbjct: 1207 -GIGGEKAGGFAPYYGDEP 1224
Score = 77.4 bits (189), Expect = 1e-13
Identities = 110/363 (30%), Positives = 127/363 (34%), Gaps = 43/363 (11%)
Query: 82 LGGAGGGAPQPGPDMEQPQHGGAKDSAAG--GQADPPGPPLLSKPGDEDDAPPKMGEP-A 138
L G G PGP P KD G G PG P +S P + P + G P A
Sbjct: 880 LPGPPGSNGNPGPP--GPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGA 937
Query: 139 GGRYEHPG-LGALG-TQQPPVAVPGGGGGPAAVPEFNNYYG-SAAPASGGPGGRAGPCFD 195
G PG LG G T +A P G GP P G S P + G G GP
Sbjct: 938 QGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGP--- 994
Query: 196 QHGGQQSPGMGMMHSASAAAAGAPGS--MDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGG 253
G Q PG+ + G PGS + S G + N PG PGA G G
Sbjct: 995 -PGPQGLPGLAGT-AGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPG--APGAPGHPG 1050
Query: 254 GGG--GGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLS 311
G G G SG G G AG GA A + A G G G G++ G
Sbjct: 1051 PPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRG 1110
Query: 312 SPRQQGGGMMMGPGGGGAASLSKAAAGSAA----GGFQRFAGQNQHPSGATPTLNQLLTS 367
P G GP G A S AG G G + HP P
Sbjct: 1111 FPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGP-------- 1162
Query: 368 PSPM----MRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGA 423
P P R GS P + PP PP P G GG AAA G+G +
Sbjct: 1163 PGPRGNRGERGSEGS-PGHPGQPGPPGPPGAP-------GPCCGGVGAAAIAGIGGEKAG 1214
Query: 424 QYA 426
+A
Sbjct: 1215 GFA 1217
Score = 65.5 bits (158), Expect = 6e-10
Identities = 126/538 (23%), Positives = 164/538 (30%), Gaps = 110/538 (20%)
Query: 547 PQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSS 606
PQPP P + P Q P+ D G R+ P PG+P P S
Sbjct: 89 PQPPTAPTR----PPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPG----------SPGS 134
Query: 607 LPDLSGSIDDLPTGTE--------ATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLS 658
P G + PTG + + S V+ G G PA P P P S
Sbjct: 135 -PGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPG----PAGPP-GPPGPPGTS 188
Query: 659 SIPGGP-SPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESS--SHPALSQSP- 714
PG P SP G P ++GP P PG+ P P G ES P P
Sbjct: 189 GHPGSPGSPGYQGPP--GEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPG 246
Query: 715 ------------MPQERGFMAGTQRNPQMAQYG----------PQQTGP--SMSPHPSPG 750
P +G RN + + G P + G M P +PG
Sbjct: 247 PPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPG 306
Query: 751 GQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSA--SYSGPGPGMGISAN 808
+ G+ + + Q GP G PP +G P + + GP +N
Sbjct: 307 ERGRPGLPGAAGARGNDGARGSDGQPGPPG----PPGTAGFPGSPGAKGEVGPAGSPGSN 362
Query: 809 NQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPG-------MG 861
+G P G AG Q P P ++ M G PG G
Sbjct: 363 GAPGQRGEPGPQG--------HAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARG 414
Query: 862 PPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMA----------SSSPYSQP 911
PP P A + N A+ G ++G+ SP
Sbjct: 415 PPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPG 474
Query: 912 MNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPES 971
N + P PA N PGE K E G P P
Sbjct: 475 ANGLPGAAGERGAPGFRGPAGPNG-----------IPGE-------KGPAGERGAPGPAG 516
Query: 972 KSKDSYSSQGISQPPTPGNLPVP-SPMSPSSASISSFHGDESDSISSPGWPKTPSSPK 1028
+ P PG +P SP P S G + +S PG P PS P+
Sbjct: 517 PRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGES-GRPG-PPGPSGPR 572
Score = 63.9 bits (154), Expect = 2e-09
Identities = 89/334 (26%), Positives = 115/334 (34%), Gaps = 59/334 (17%)
Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLL-------SKPGDE-----DDAP 131
G G PGP + + G + G+ PPGP L +PG + D P
Sbjct: 963 GMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLP 1022
Query: 132 PKMGEPAG--GRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG-GPGG 188
+ G P G R E+ GA G P P G GPA G A PA GP G
Sbjct: 1023 GRDGSPGGKGDRGENGSPGAPGAPGHPG--PPGPVGPAGKSGDRGESGPAGPAGAPGPAG 1080
Query: 189 RAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGA 248
G G Q P + AAG G H G+P + PGA
Sbjct: 1081 SRGA-----PGPQGPRGDKGETGERGAAGIKG--------HRGFPGN----------PGA 1117
Query: 249 GGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYG 308
G G G G G G AG G + + G G G G+ G
Sbjct: 1118 PGSPGPAGQ----QGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERG 1173
Query: 309 VLSSPRQQGGGMMMGP--------GGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPT 360
SP G GP GG GAA+++ G AGGF + G P
Sbjct: 1174 SEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIA-GIGGEKAGGFAPYYG--DEPMDFKIN 1230
Query: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQ 394
++++TS ++S G SP P++
Sbjct: 1231 TDEIMTS----LKSVNGQIESLISPDGSRKNPAR 1260
Score = 33.9 bits (76), Expect = 1.8
Identities = 37/129 (28%), Positives = 44/129 (34%), Gaps = 13/129 (10%)
Query: 76 ISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMG 135
I + G G PGP +Q G + G P GPP K G P +G
Sbjct: 1105 IKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPP--GKDGTSGH-PGPIG 1161
Query: 136 EPA--GGRYEHPGLGALG-TQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGP 192
P G R E G+ G QP P G GP G A A G GG
Sbjct: 1162 PPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCC-------GGVGAAAIAGIGGEKAG 1214
Query: 193 CFDQHGGQQ 201
F + G +
Sbjct: 1215 GFAPYYGDE 1223
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 119 bits (299), Expect = 3e-26
Identities = 335/1548 (21%), Positives = 492/1548 (31%), Gaps = 201/1548 (12%)
Query: 15 GEAPAAPPHQQHHHHHHAHHHHHH----AHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQ 70
G +P+ H H +H H + H+ + Q + F Q + Q Q
Sbjct: 773 GHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHG 832
Query: 71 QQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDA 130
S+ G G Q G DS++G S G + A
Sbjct: 833 SASGHFSSQGRHGSTSG----------QSSSSGQHDSSSGQS---------SSYGQHESA 873
Query: 131 PPKM---GEPAGGRYEHPGLGALGT---QQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG 184
G G + PG G G+ Q P G G G ++ + +GS + S
Sbjct: 874 SHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSS---SGRHGSGSGQSS 930
Query: 185 GPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSH---EGYPNSQCNHYP 241
G G ++ Q G G G HS+S G+ H G +S H
Sbjct: 931 GFGHKSSS--GQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGS 988
Query: 242 GYSRPGAGGGGGGGGGG----------GGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAA 291
G SR G G G G G G GSG G +G + + + + +
Sbjct: 989 G-SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHS 1047
Query: 292 AGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQN 351
+G G G S+GYG S G G G+ S ++ G + +
Sbjct: 1048 SGLGHRESRSGQSSGYGQHGS----SSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHG 1103
Query: 352 QHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQA 411
QH SG++ + S S G P + + + +G ++ Q
Sbjct: 1104 QHGSGSSQS------SGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH 1157
Query: 412 AAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPG--TPGPTMGRSQGSPMDPMVMKRPQ 469
+G+G G +++ + + +Q S S G G G+S
Sbjct: 1158 GSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSS 1217
Query: 470 LYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTP----GAMAGMQYPQQQMPPQ 525
YG + Q GS P R+ G+ + G+ +G + +
Sbjct: 1218 HYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESR 1277
Query: 526 YGQQGVSGYCQQGQ--QPYYSQQPQPP-HLPPQAQYLPSQSQQRYQPQQDMS---QEGYG 579
G V G + G YSQ H Q Q+ + Q Q+ S YG
Sbjct: 1278 SGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYG 1337
Query: 580 TR-SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQ 638
R S + G H + PS SGS G + S S+SG S
Sbjct: 1338 HRGSGSSQSSGYGRH---GAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 1394
Query: 639 GDQSNPAQSPFSPHASP--HLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQ 696
QS S F H S S S S S + SRSG S GS
Sbjct: 1395 SGQS----SGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSS 1450
Query: 697 PPGSQSESSSHPALS---------QSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHP 747
Q S S +L QSP P +G+ ++ + YG +G S S P
Sbjct: 1451 SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYG-SGSGWSSSRGP 1509
Query: 748 SPGGQMHAGISSFQQSNS--SGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGI 805
G H+ ++S S S YG S G + + + SG S+S G G
Sbjct: 1510 YESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSG-QSSSCGQHGASSGQ 1568
Query: 806 SANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQG-GPGM---- 860
S+++ HG G SQ G GR S Q+ P G S + SP + G G G
Sbjct: 1569 SSSHGQHGSGSSQSSG---YGRQGSGSGQS-PGHGQRGSGSRQSPSYGRHGSGSGRSSSS 1624
Query: 861 ---GPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSS 917
G + + +++ ++ + S G G Q G + S + +SS
Sbjct: 1625 GQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSR 1684
Query: 918 LMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSY 977
+ S + G S G L + + G+ S S+ Y
Sbjct: 1685 SSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPY 1744
Query: 978 SSQGISQPPTPGNLPVPSPMSPSSASISSF--HGDESDSISSPGWPKTPSSPKSSSSTTT 1035
S+ G+ V S S++ HG S S G + S +SS+
Sbjct: 1745 ESRS-------GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSG-QSSTFDQE 1796
Query: 1036 GEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGL 1095
G + G Y ++GS P+ G+
Sbjct: 1797 GSSTGQSSSHGQHGSGSSQSSSY----GQQGSGSGQSPSRGRHGSGS-------GHSSSY 1845
Query: 1096 AQVNKNKKWRELATNLNVGTSSSA-------ASSLKKQYIQYLFAFECKIERGEEPPPEV 1148
Q W + G+ S+ +S Y Q+ G E
Sbjct: 1846 GQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSG------SGHSSSYEQ 1899
Query: 1149 FSTGDTKKQPKLQPPSPANSGSLQGPQ---TPQSTGSNSMAEVPGDLKPPTPASTPHGQM 1205
+ + Q S + S S G + QS G G + P+P+ HG
Sbjct: 1900 HGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSG--QSPSPSRGRHGSG 1957
Query: 1206 TPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFG 1265
+ G+SS+ + S S S PY+ G +G E
Sbjct: 1958 S----GQSSSYGPYGSGSGWSSS----------RGPYESGSGHSSGLGHR--ESRSGQSS 2001
Query: 1266 GMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYG 1325
G + SS T GQ ++S QS S GQ S + YG
Sbjct: 2002 GYGQHGSSSGHSSTHGQHGSAS-----GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG 2056
Query: 1326 QQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRH--------MDGMYGPPAKRHEGDMYNMQ 1377
+Q G SGQ P G + Q P+Y RH G +GP G ++ +
Sbjct: 2057 RQ----GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHH-E 2111
Query: 1378 YSSQQQEMYNQYG------------GSYSGPDRR-PIQGQYPYPYSRERMQGPGQIQTHG 1424
SS Q Y+Q+G GS SG R G SR G G Q+ G
Sbjct: 2112 SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSG 2171
Query: 1425 IPPQMMG----------GPLQSSSSEGPQQNMWAARNDMPYPYQNRQG 1462
Q G G SS Q + R+ PY++R G
Sbjct: 2172 HGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSG 2219
Score = 105 bits (262), Expect = 5e-22
Identities = 320/1442 (22%), Positives = 484/1442 (33%), Gaps = 233/1442 (16%)
Query: 74 HPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPK 133
H S+ +S G G+ G QHG ++ G+ + G +
Sbjct: 468 HESSSEHSSGYTQHGSGS-GHSSGHGQHGSRSGQSSRGE----------RQGSSAGSSSS 516
Query: 134 MGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNY----YGSAAPASGGP--- 186
G+ G + G G+ P G + + ++Y YGS +S GP
Sbjct: 517 YGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYES 576
Query: 187 --GGRAGPCFDQHGGQQSPGMGMMHSAS---------------AAAAGAPGSMDPLQNSH 229
G +G + QS G G S+S +++ G G+ +SH
Sbjct: 577 GSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSH 636
Query: 230 EGYPNSQCNHYPGYSRPGAGGG-----GGGGGGGGGGSGGGGGGGGAGAGGAGA--GAVA 282
G S + Y + G+G G G G G S G G G+G + G+V+
Sbjct: 637 -GQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVS 695
Query: 283 AAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQG--GGMMMGPGGGGAASLSKAAAGSA 340
++ +G G GY +G S R+ G G G++S ++ G
Sbjct: 696 GQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQH 755
Query: 341 AGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAA 400
G + +G + SG+ + +++ S S G + +S S S +
Sbjct: 756 GSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCS------SSCGHYES 809
Query: 401 AAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPM 460
+G A+G Q +G G G +Q+ +AS ++ S G G T G+S S
Sbjct: 810 GSGQASGFGQHESGSGQGY---SQHGSASGHFS----------SQGRHGSTSGQSSSSGQ 856
Query: 461 DPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTP-----GAMAGM 515
+ YG + + GS PG + G G++P G+ +G
Sbjct: 857 HDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSG-SGQSPSYGRHGSGSGR 915
Query: 516 QYPQQQMPPQYGQQGVSGY-CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMS 574
+ GQ G+ GQ Y+Q + S+S Q + +Q S
Sbjct: 916 SSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGS 975
Query: 575 QEG-------YGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSS 627
G +G+ S+ L G+ Q PS SGS G ++
Sbjct: 976 SSGSSSSYGQHGSGSRQSLGHGQ---HGSGSGQSPSPSRGRHGSGS------GQSSSYGP 1026
Query: 628 AVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPAS 687
S SG +SS+G P +S S H S + S S S G + S SG S
Sbjct: 1027 YRSGSGWSSSRG----PYES-----GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG 1077
Query: 688 IPGSQMPPQPPGSQSESSSHPALS-QSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSP- 745
GS G S H A S QS + G + Q + YG Q +G SP
Sbjct: 1078 QHGS-----TSGQSSSCGQHGASSGQSSSHGQHG-----SGSSQSSGYGRQGSGSGQSPG 1127
Query: 746 --------HPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYS 797
SP H S +S+SSG +G S G + + SG S+SYS
Sbjct: 1128 HGQRGSGSRQSPSYGRHG--SGSGRSSSSGQHG---SGLGESSGFGHHESSSG-QSSSYS 1181
Query: 798 GPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGG 857
G G G S+ HG Q S G ++ G+ S G Q G
Sbjct: 1182 QHGSGSGHSSGYGQHGSRSGQ----------SSRGERHGSSSGSSSHYGQHGSGSRQSSG 1231
Query: 858 PGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSS--PYSQPMNNS 915
G R+ + + + S S G + SG SSS PY +S
Sbjct: 1232 HG---------RQGSGSGHSPSRGRHGSGLGHSSSH-GQHGSGSGRSSSRGPYESRSGHS 1281
Query: 916 SSL-MNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSK 974
S + +S A + S G S G+ + +EG+ +S S
Sbjct: 1282 SVFGQHESGSGHSSAYSQHGS-----GSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSY 1336
Query: 975 DSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDES---DSISSPGWPKTPSSPKSSS 1031
+ G SQ G S SPS S G S S GW + S S
Sbjct: 1337 -GHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 1395
Query: 1032 STTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKE 1091
++G G+ E W T SS G +
Sbjct: 1396 GQSSG--------FGHH-ESSSWQSSGCTQHGSGSGHSSSYEQHGSRS------------ 1434
Query: 1092 IGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQ---YIQYLFAFECKIERGEEPPPEV 1148
Q ++ ++ G+SS ++SS + Q L + G+ P P
Sbjct: 1435 ----GQSSRGERH---------GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR 1481
Query: 1149 FSTGDTKKQPKLQPPSPANSG--SLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMT 1206
G Q P + SG S +GP S+ S+ + G + + S+ +GQ
Sbjct: 1482 GRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGL----GHRESRSGQSSGYGQ-H 1536
Query: 1207 PMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQ---GMSMPDVMGRMPYEPNKDP 1263
G SST H S S S S ++ + Q G S GR + P
Sbjct: 1537 GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP 1596
Query: 1264 FGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEP 1323
G R P + G+ + S +S S G+G+ F + S +
Sbjct: 1597 GHGQRGSGSRQSP--SYGRHGSGS-----GRSSSSGQHGSGLGESSGFGHHESSSGQSSS 1649
Query: 1324 YGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQ 1383
Y Q G G SG +G Q +RH + Y S +Q
Sbjct: 1650 YSQHGSGSGHSSGYGQHGSRS----GQSSRGERH-------GSSSRSSSRYGQHGSGSRQ 1698
Query: 1384 EMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQ 1443
+ +G SG + P +G++ G G +HG G SSS GP
Sbjct: 1699 S--SGHGRQGSGSGQSPSRGRHG--------SGLGHSSSHG----QHGSGSGRSSSRGPY 1744
Query: 1444 QN 1445
++
Sbjct: 1745 ES 1746
Score = 103 bits (256), Expect = 2e-21
Identities = 314/1414 (22%), Positives = 457/1414 (32%), Gaps = 223/1414 (15%)
Query: 73 QHPISNNNSLG-GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAP 131
QH + SLG G G P + +HG ++ G S G +
Sbjct: 1455 QHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGS 1514
Query: 132 PK---MGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGG 188
+G + G G G+ + G G + +G+++ S G
Sbjct: 1515 SHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQ 1574
Query: 189 RAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGA 248
G QS G G S S + G G S P Y R G+
Sbjct: 1575 HGS------GSSQSSGYGRQGSGSGQSPG------------HGQRGSGSRQSPSYGRHGS 1616
Query: 249 GGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGG--GGGYGGSSAG 306
G G G G G G G +G + + + + + G G G G SS G
Sbjct: 1617 GSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 1676
Query: 307 YGVLSSPR------QQGGGMMMGPGGG--GAASLSKAAAGSAAGGFQRFAGQNQHPSGAT 358
SS R Q G G G G G+ S + G G + QH SG+
Sbjct: 1677 ERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSG 1736
Query: 359 PTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLG 418
+ ++ P + + ++ S S S A + + G + G G
Sbjct: 1737 RSSSR---GPYESRSGHSSVFGQHESGSG--------HSSAYSQHGSGSGHFCSQGQH-G 1784
Query: 419 KDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPH 478
G + Q SH G+ + QGS G G +P
Sbjct: 1785 STSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGS-------------GSGQSPS 1831
Query: 479 SQPQQSSPYPGGSYGPPGP---QRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYC 535
S SYG G G G G +G + + SGY
Sbjct: 1832 RGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHES------SSWQSSGYT 1885
Query: 536 QQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEG-YGTRSQPPLAPGKPNHE 594
Q G +S + H Q S+ +Q S G +G+ S+ L G+
Sbjct: 1886 QHGSGSGHSSSYE-QHGSRSGQ--SSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQ---H 1939
Query: 595 DLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHAS 654
Q PS SGS G ++ S SG +SS+G P +S S
Sbjct: 1940 GSGSGQSPSPSRGRHGSGS------GQSSSYGPYGSGSGWSSSRG----PYES-----GS 1984
Query: 655 PHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALS-QS 713
H S + S S S G + S SG S GS G S H A S QS
Sbjct: 1985 GHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS-----ASGQSSSCGQHGASSGQS 2039
Query: 714 PMPQERGFMAGTQRNPQMAQYGPQQTGPSMSP---------HPSPGGQMHAGISSFQQSN 764
+ G + Q + YG Q +G SP SP H S +S+
Sbjct: 2040 SSHGQHG-----SGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHG--SGSGRSS 2092
Query: 765 SSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVP 824
SSG +GP + + G++ S S+SYS G G G S+ HG Q
Sbjct: 2093 SSGQHGPGLGESSGFGHHES----SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 2148
Query: 825 LGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQG-GPGMGPPMPTVNRKAQEAAAAVMQAAA 883
G S+G +R G S + S G +QG G G P + + + +
Sbjct: 2149 HG--SSSGSSSR--YGQHGSGSRQSSGHGRQGSGSGHSP------SRGRHGSG----SGH 2194
Query: 884 NSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSL-MNTQAPPYSMAPAMVNSSAASVGL 942
+S+ + GS SG +S PY +SS + +S A + S G
Sbjct: 2195 SSSHGQHGS-----GSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGS-----GS 2244
Query: 943 ADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSA 1002
S G+ + +EG+ +S S + S G SQ + G S SPS
Sbjct: 2245 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGS-GSSQSSSYGQQGSGSGQSPSRG 2303
Query: 1003 SISSFHGDES---DSISSPGWPKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYL 1059
S G S S GW + S S ++G G+ E W
Sbjct: 2304 RHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSG--------FGHH-ESSSWQSSGY 2354
Query: 1060 TFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSA 1119
T SS G + Q ++ ++ G+SS +
Sbjct: 2355 TQHGSGSGHSSSYEQHGSRS----------------GQSSRGERH---------GSSSGS 2389
Query: 1120 ASSLKKQ---YIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSG--SLQGP 1174
+SS + Q L + G+ P P G Q P + SG S +GP
Sbjct: 2390 SSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGP 2449
Query: 1175 QTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRN 1234
S S+ + G + + S+ +GQ G SST H S S S
Sbjct: 2450 YESGSGHSSGL----GHRESRSGQSSGYGQ-HGSSSGHSSTHGQHGSTSGQSSSCGQHGA 2504
Query: 1235 SMTPNAPYQQ---GMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDM 1291
S ++ + Q G S GR + P G R P + G+ + S
Sbjct: 2505 SSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSP--SYGRHGSGS---- 2558
Query: 1292 YNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQ 1351
+S S G+G+ F + S + Y Q G G SG +G Q
Sbjct: 2559 -GRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS----GQS 2613
Query: 1352 PNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSR 1411
+RH + Y S +Q + +G SG + P +G++
Sbjct: 2614 SRGERH-------GSSSGSSSHYGQHGSGSRQS--SGHGRQGSGSGQSPSRGRHG----- 2659
Query: 1412 ERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQN 1445
G G +HG G SSS GP ++
Sbjct: 2660 ---SGLGHSSSHG----QHGSGSGRSSSRGPYES 2686
Score = 100 bits (248), Expect = 2e-20
Identities = 234/1026 (22%), Positives = 344/1026 (33%), Gaps = 128/1026 (12%)
Query: 73 QHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPP 132
QH S+ S G + G+ G QHG ++ G+ + +
Sbjct: 233 QHKSSSGQSSGYSQHGSGS-GHSSGYGQHGSRSGQSSRGE----------RHRSSSGSSS 281
Query: 133 KMGEPAGGRYEHPGLG--ALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGG---PG 187
G+ G + G G G++Q P V G G + + GS+ S G G
Sbjct: 282 SYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESG 341
Query: 188 GRAGPCFDQH-------GGQQSPGMGMMHSAS----------AAAAGAPGSMDPLQNSHE 230
F QH G G G HS+S A+++G GS Q+S
Sbjct: 342 SGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSR-QSSSY 400
Query: 231 GYPNSQCNHYPGYSRPGAGGGGGGGGGG-GGGSGGGGGGGGAGAGGAGAGAVAAAAAAAA 289
G S H G + +G G G G G GSG G G G ++++
Sbjct: 401 GQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTG------FGRSSSSGP 454
Query: 290 AAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAA-----GSAAGGF 344
+G G G+G + S Q G G G G S S ++ GS+AG
Sbjct: 455 YVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSS 514
Query: 345 QRFAGQNQHPSGATPTLNQLL------TSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ 398
+ QH SG+ +L SPSP G + S S+ P +
Sbjct: 515 SSY---GQHGSGSRQSLGHSRHGSGSGQSPSPSR----GRHESGSRQSSSYGPHGYGSGR 567
Query: 399 AAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGS 458
+++ G G ++G+G + Q S + S + + G G T G+S
Sbjct: 568 SSSRGPYESGSGHSSGLGHQESRSGQ----SSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 623
Query: 459 PMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTP----GAMAG 514
+ +G + SQ + GS P R+ + G+ +G
Sbjct: 624 GQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSG 683
Query: 515 MQYPQQQMPPQYGQQGVSGY-CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDM 573
GQ G+ GQ YSQ + S+S Q + +Q
Sbjct: 684 WSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHG 743
Query: 574 SQEG-------YGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLS 626
S G +G+ S G+ + + R S S S +GT + S
Sbjct: 744 SSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSS 803
Query: 627 SA--VSASGSTSSQGDQSNPAQSPFSPH--ASPHLSSIPGGPSPSPVGSPVGSNQSRSGP 682
S SG S G + + +S H AS H SS S S S G + S SG
Sbjct: 804 CGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQ 863
Query: 683 ISPASIPGSQMPPQPPGSQSESSSHPA---------LSQSPMPQERGFMAGTQRNPQMAQ 733
S Q ES+SH A QSP +RG +G+ ++P +
Sbjct: 864 SSSY-------------GQHESASHHASGRGRHGSGSGQSPGHGQRG--SGSGQSPSYGR 908
Query: 734 YGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPS 793
+G S S G +G S S Y S G +Y + + SG S
Sbjct: 909 HGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSS 968
Query: 794 ASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMS 853
S G G S++ HG G Q G G +G P P S G S
Sbjct: 969 RS-EQHGSSSGSSSSYGQHGSGSRQSLGHGQHG----SGSGQSPSPSR--GRHGSGSGQS 1021
Query: 854 QQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMN 913
GP + +R E+ + + +SR G G Q G +SS S
Sbjct: 1022 SSYGPYRSGSGWSSSRGPYESGSG-HSSGLGHRESRSGQSSGYGQHG--SSSGHSSTHGQ 1078
Query: 914 NSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKS 973
+ S+ + + A + +SS G S G + +G+ +S
Sbjct: 1079 HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGR-----------QGSGSGQSPG 1127
Query: 974 KDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDES---DSISSPGWPKTPSSPKSS 1030
S G Q P+ G S S SS S G+ S SS G + S S
Sbjct: 1128 HGQRGS-GSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG 1186
Query: 1031 SSTTTG 1036
S ++G
Sbjct: 1187 SGHSSG 1192
Score = 92.8 bits (229), Expect = 3e-18
Identities = 323/1503 (21%), Positives = 472/1503 (31%), Gaps = 182/1503 (12%)
Query: 67 QQQQQQQHPISN--NNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKP 124
Q + +QH S+ ++S G G G+ Q Q G S + +
Sbjct: 735 QSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQH 794
Query: 125 GDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG 184
G G G + G G + G G G + + ++ S
Sbjct: 795 GSGTSCSSSCGHYESGSGQASGFGQHES--------GSGQGYSQHGSASGHFSSQGRHGS 846
Query: 185 GPGGRAGPCFDQHGGQQSPGMGMMHSAS--AAAAGAPGSMDPLQNSHEGYPNSQCNHYPG 242
G + QS G SAS A+ G GS H G S P
Sbjct: 847 TSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGH-GQRGSGSGQSPS 905
Query: 243 YSRPGAGGGGGGGGGG-GGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAA----GGGGG 297
Y R G+G G G G GSG G G + G +G + + +++ G G
Sbjct: 906 YGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSG 965
Query: 298 --------GGYGGSSAGYGVLSS-PRQQGGGMMMGPGGGGAASLSKAAAGSAAG------ 342
G GSS+ YG S RQ G G G G + S S+ GS +G
Sbjct: 966 QSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYG 1025
Query: 343 ------GFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYG--GSYPEYSSPSAPPPPPSQ 394
G+ G + SG + L S S YG GS +SS S
Sbjct: 1026 PYRSGSGWSSSRGPYESGSGHSSGLGHR-ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSG 1084
Query: 395 PQSQAAAAGAAAGGQQAAAGMGLGKDMGAQY------AAASPAWAAAQQRSHPAMSPGTP 448
S GA++G + G G + Y + SP S + S G
Sbjct: 1085 QSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 1144
Query: 449 GPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGS-----YGPPGPQRYPIG 503
G GRS S + +G + Q S + GS YG G R
Sbjct: 1145 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHG-SRSGQS 1203
Query: 504 IQGRTPGAMAGMQYPQQQMPPQYGQQGV-----SGYCQQGQQPYYSQQPQPPHLPPQAQY 558
+G G+ +G YGQ G SG+ +QG +S P +
Sbjct: 1204 SRGERHGSSSGSS-------SHYGQHGSGSRQSSGHGRQGSGSGHS--PSRGRHGSGLGH 1254
Query: 559 LPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGK----PNHEDL---------NLIQQERPS 605
S Q + S+ Y +RS G+ H + Q +
Sbjct: 1255 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHG 1314
Query: 606 SLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPS 665
S S + D + T + S SGS+ S G + A S SP H S
Sbjct: 1315 STSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSG------ 1368
Query: 666 PSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGT 725
S S G + S SG S + GS ESSS QS + G +G+
Sbjct: 1369 -SGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSW----QSSGCTQHG--SGS 1421
Query: 726 QRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRP 785
+ Q+G + S G+ H SS S+S G +G Q G +
Sbjct: 1422 GHSSSYEQHGSRSGQSSR-------GERHG--SSSGSSSSYGQHGSGSRQSLGHGQHGSG 1472
Query: 786 PAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSM 845
S PS G G G S + G G S G G S+G+ G+ S
Sbjct: 1473 SGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGL------GHRESR 1526
Query: 846 TPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASS 905
+ S G Q G + +++ Q A+S QS S G + SG + S
Sbjct: 1527 SGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQS---SSHGQHGSG-SSQS 1582
Query: 906 SPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEG 965
S Y + + S Q+P + G SP + G
Sbjct: 1583 SGYGRQGSGSG-----QSPGHGQR-----------GSGSRQSPSYGR-----------HG 1615
Query: 966 TPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPS 1025
+ S S + S G+ + G+ SS SS+ S S S G+ + S
Sbjct: 1616 SGSGRSSSSGQHGS-GLGESSGFGH------HESSSGQSSSYSQHGSGSGHSSGYGQHGS 1668
Query: 1026 -SPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFR 1084
S +SS G G R + +GS P+ G+ L
Sbjct: 1669 RSGQSSRGERHGSSSRSSSRYGQHGSGS----RQSSGHGRQGSGSGQSPSRGRHGSGLGH 1724
Query: 1085 LYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEP 1144
+ G + + + + + +V + S Y Q+ +G+
Sbjct: 1725 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQH- 1783
Query: 1145 PPEVFSTGDTKKQPKL--QPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPH 1202
G T Q Q S S G S+ S+S + G +P+ H
Sbjct: 1784 -------GSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQ-QGSGSGQSPSRGRH 1835
Query: 1203 GQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKD 1262
G + G SS+ H S S SS + ++ + S +
Sbjct: 1836 GSGS----GHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGS 1891
Query: 1263 PFGGMRKVPGSSEPFMTQGQMPNSSM--QDMYNQSPSGAMSNLGMGQRQQFPYGASYDRR 1320
+ GS ++G+ SS Y Q SG+ +LG GQ +G+ +
Sbjct: 1892 GHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQ-----HGSGSGQS 1946
Query: 1321 HEP-YGQQYPGQGPPSGQPPYGGHQPGLYPQQP--NYKRHMDGMYGPPAKRHEGDMYNMQ 1377
P G+ G G S PYG + P + H G+ ++ + Y
Sbjct: 1947 PSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQH 2006
Query: 1378 YSSQQQEMYNQYGGSYSGPDRRPIQ-GQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQS 1436
SS + GS SG Q G S G G Q+ G Q G S
Sbjct: 2007 GSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG----S 2062
Query: 1437 SSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPS 1496
S G Q +R Y + PG+ + + S +
Sbjct: 2063 GQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQ 2122
Query: 1497 HVS 1499
H S
Sbjct: 2123 HGS 2125
Score = 92.0 bits (227), Expect = 6e-18
Identities = 324/1469 (22%), Positives = 478/1469 (32%), Gaps = 210/1469 (14%)
Query: 100 QHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAV 159
QHG ++ G+ + G + G+ G + G G G+
Sbjct: 1195 QHGSRSGQSSRGE----------RHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPS 1244
Query: 160 PGGGGGPAAVPEFNNYYGSAAPASGGPG---GRAG--PCFDQH---GGQQSP----GMGM 207
G G + +GS + S G R+G F QH G S G G
Sbjct: 1245 RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS 1304
Query: 208 MHSASAAAAGAPGSMDPL---------QNSHEGYPNSQCNHYPGYSRPGAGGG------- 251
H S G+ Q+S G+ S + GY R GAG G
Sbjct: 1305 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGR 1364
Query: 252 -GGGGG--------GGGGGSGGGGGGGGAGAG-GAGAGAVAAAAAAAAAAAGGGGGGGYG 301
G G G G G G G G+G+G +G G +++ ++ G G G+
Sbjct: 1365 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHS 1424
Query: 302 GSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTL 361
S +G S +G G++S S ++ G G ++ G QH SG+
Sbjct: 1425 SSYEQHGSRSGQSSRGERH-------GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQ-- 1475
Query: 362 NQLLTSPSPMMRSYGG------SYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGM 415
SPSP +G SY Y S S P ++ + G +++ +G
Sbjct: 1476 -----SPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRG-PYESGSSHSSGLGHRESRSGQ 1529
Query: 416 GLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQ-----GSPMDPMVMKRPQL 470
G + S S + S G G + G+S GS Q
Sbjct: 1530 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 1589
Query: 471 YGMGSNPHSQPQQSSPYPGGSYGPPGP---QRYPIGIQGRTPGAMAGMQYPQQQ--MPPQ 525
G G +P + S SYG G + G G G +G + +
Sbjct: 1590 SGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSS 1649
Query: 526 YGQQGV-----SGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGT 580
Y Q G SGY Q G + S + + S+S RY Q G G+
Sbjct: 1650 YSQHGSGSGHSSGYGQHGSRSGQSSRGE-------RHGSSSRSSSRY------GQHGSGS 1696
Query: 581 RSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGD 640
R H + PS SG G ++ S SG +SS+G
Sbjct: 1697 RQSS-------GHGRQGSGSGQSPSRGRHGSG------LGHSSSHGQHGSGSGRSSSRGP 1743
Query: 641 QSNPA--QSPFSPH--ASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQ 696
+ + S F H S H S+ S S G + S SG S GS
Sbjct: 1744 YESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGS----- 1798
Query: 697 PPGSQSESSSH----PALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQ 752
S +SSSH SQS ++G +G+ ++P ++G S S H S GQ
Sbjct: 1799 ---STGQSSSHGQHGSGSSQSSSYGQQG--SGSGQSPSRGRHG------SGSGHSSSYGQ 1847
Query: 753 MHAGISSFQQSNSSGTYGPQMSQYG-------PQGNYSRPPAYSGVPSASYSGPGPGMGI 805
+G S G+ Q S +G Y++ + SG S+SY G G
Sbjct: 1848 HGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSG-HSSSYEQHGSRSGQ 1906
Query: 806 SANNQMHGQ--GPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPS------SPGMSQQGG 857
S+ + HG G S G G S G + G+ S +PS G S G
Sbjct: 1907 SSRGEQHGSSSGSSSSYGQHGSGSRQSLG-HGQHGSGSGQSPSPSRGRHGSGSGQSSSYG 1965
Query: 858 PGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQP--MNNS 915
P + +R E+ + + +SR G G Q G SSS +S + S
Sbjct: 1966 PYGSGSGWSSSRGPYESGSG-HSSGLGHRESRSGQSSGYGQHG---SSSGHSSTHGQHGS 2021
Query: 916 SSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKD 975
+S ++ + + +SS G S G + G+ G Q S S+
Sbjct: 2022 ASGQSSSCGQHGASSGQ-SSSHGQHGSGSSQSSGYGRQG---SGSGQSPGHGQRGSGSRQ 2077
Query: 976 S-----------YSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTP 1024
S SS P G SS SS+ S S S G+ +
Sbjct: 2078 SPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHG 2137
Query: 1025 S-SPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLF 1083
S S +SS G G R + +GS P+ G+
Sbjct: 2138 SRSGQSSRGERHGSSSGSSSRYGQHGSGS----RQSSGHGRQGSGSGHSPSRGRHGSGSG 2193
Query: 1084 RLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEE 1143
+ G + + + + + +V + S Y Q+ +G+
Sbjct: 2194 HSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQH 2253
Query: 1144 PPPEVFSTGDTKKQPKL--QPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTP 1201
G T Q Q S S G S+ S+S + G +P+
Sbjct: 2254 --------GSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQ-QGSGSGQSPSRGR 2304
Query: 1202 HGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNK 1261
HG + G SS+ H S S SS + ++ + S +
Sbjct: 2305 HGSGS----GHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSG 2360
Query: 1262 DPFGGMRKVPGSSEPFMTQGQMPNSSM--QDMYNQSPSGAMSNLGMGQRQQFPYGASYDR 1319
+ GS ++G+ SS Y Q SG+ +LG GQ +G+ +
Sbjct: 2361 SGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQ-----HGSGSGQ 2415
Query: 1320 RHEP-YGQQYPGQGPPSGQPPYGGHQPGLYPQQP--NYKRHMDGMYGPPAKRHEGDMYNM 1376
P G+ G G S PYG + P + H G+ ++ + Y
Sbjct: 2416 SPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQ 2475
Query: 1377 QYSSQQQEMYNQYGGSYSGPDRRPIQ-GQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQ 1435
SS + GS SG Q G S G G Q+ G Q G
Sbjct: 2476 HGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG---- 2531
Query: 1436 SSSSEGPQQNMWAARNDMPYPYQNRQGPG 1464
S S G Q +R P R G G
Sbjct: 2532 SGQSPGHGQRGSGSRQS---PSYGRHGSG 2557
Score = 90.9 bits (224), Expect = 1e-17
Identities = 250/1097 (22%), Positives = 361/1097 (32%), Gaps = 194/1097 (17%)
Query: 38 HAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDME 97
H+ L H + Q + + Q Q S + G G
Sbjct: 1516 HSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHG----STSGQSSSCGQHGASSGQSSS 1571
Query: 98 QPQHGGAKDSAAG------GQADPPG----------PPLLSKPGDEDDAPPKMGEPAGGR 141
QHG ++G G PG P + G G+ G
Sbjct: 1572 HGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGL 1631
Query: 142 YEHPGLG---ALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG--------GPGGRA 190
E G G + Q + G G G ++ YG SG G R+
Sbjct: 1632 GESSGFGHHESSSGQSSSYSQHGSGSG------HSSGYGQHGSRSGQSSRGERHGSSSRS 1685
Query: 191 GPCFDQHGGQ---------------QSP-----GMGMMHSAS----AAAAGAPGSMDPLQ 226
+ QHG QSP G G+ HS+S + +G S P +
Sbjct: 1686 SSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYE 1745
Query: 227 N-----SHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGG--------GGGGGGAGA 273
+ S G S H YS+ G+G G G G + G G G + +
Sbjct: 1746 SRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 1805
Query: 274 GGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGG--GAAS 331
G + +++ +G G G +G G SS Q G G G G+ S
Sbjct: 1806 HGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 1865
Query: 332 LSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPP 391
+ G + +G QH SG+ + SY ++ S S
Sbjct: 1866 GQSSGFGHHESSSWQSSGYTQHGSGS----------------GHSSSYEQHGSRSGQS-- 1907
Query: 392 PSQPQSQAAAAGAAAGGQQAAAG--MGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPG 449
S+ + +++G+++ Q +G LG + SP+ + + S S
Sbjct: 1908 -SRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGP 1966
Query: 450 PTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTP 509
G S P G+G S+ QSS Y G +G G G
Sbjct: 1967 YGSGSGWSSSRGPYESGSGHSSGLGHR-ESRSGQSSGY--GQHGSSSGHSSTHGQHGSAS 2023
Query: 510 G--AMAGMQYPQQQMPPQYGQQGV-----SGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQ 562
G + G +GQ G SGY +QG S P
Sbjct: 2024 GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQS---------------PGH 2068
Query: 563 SQQRYQPQQDMSQEGYGTRSQPPLAPGK--PNHEDLNLIQQERPSSLPDLSGSIDDLPTG 620
Q+ +Q S +G+ S + G+ P + + SS S S +G
Sbjct: 2069 GQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSG 2128
Query: 621 TEATLSSAVSASGSTSSQGDQ---SNPAQSPFSPHASPHLSSIPGGPSPSPVG-SPV-GS 675
+ S SG SS+G++ S+ + S + H S S G S G SP G
Sbjct: 2129 HSSGYGQHGSRSGQ-SSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGR 2187
Query: 676 NQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG-FMAGTQRNPQMAQY 734
+ S SG S GS GS SS P S+S G +G+ + +Q+
Sbjct: 2188 HGSGSGHSSSHGQHGS-------GSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQH 2240
Query: 735 GPQQTG-PSMSPHPSPGGQMHAGISSFQQSNSS----------GTYGPQMSQYGPQGNYS 783
G S H S GQ S+F Q SS G+ Q S YG QG+ S
Sbjct: 2241 GSGSGHFCSQGQHGSTSGQS----STFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGS 2296
Query: 784 -------RPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNR 836
R + SG S+SY G G G S+++ HG G Q G G S+ Q+
Sbjct: 2297 GQSPSRGRHGSGSG-HSSSYGQHGSGSGWSSSSGRHGSGSGQSSG---FGHHESSSWQSS 2352
Query: 837 PFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGM 896
+ + S SS +Q G G + + ++ + + + SRQ G
Sbjct: 2353 GYTQHGSGSGHSS--SYEQHGSRSG--QSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQ 2408
Query: 897 NQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLP 956
+ SG S SP S+ + S S ++ PY + G + P ES
Sbjct: 2409 HGSGSGQSPSP-SRGRHGSGSGQSSSYSPY----------GSGSGWSSSRGPYES----- 2452
Query: 957 LKADGKEEGTPQPESKSKDS--YSSQGIS--QPPTPGNLPVPSPMSPSSASISSFHGDES 1012
G G ES+S S Y G S T G S S S HG S
Sbjct: 2453 --GSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQ----HGASS 2506
Query: 1013 DSISSPGWPKTPSSPKS 1029
SS G + SS S
Sbjct: 2507 GQSSSHGQHGSGSSQSS 2523
Score = 87.4 bits (215), Expect = 1e-16
Identities = 267/1275 (20%), Positives = 402/1275 (31%), Gaps = 205/1275 (16%)
Query: 209 HSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGG 268
H++ + + + G + +SH+ QC G S P G G G G G G
Sbjct: 169 HNSYSGQSSSYGEQN--SDSHQSSGRGQCGSGSGQS-PNYGQHGSGSGQSSSNDTHGSGS 225
Query: 269 GGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYG--GSSAGYGVLSSPRQQGGGMMMGPGG 326
G + + ++ + +G G GYG GS +G + G G
Sbjct: 226 GQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQ 285
Query: 327 GGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPS 386
G+ S G G ++ +H SG+ + S+ ++ S S
Sbjct: 286 HGSGSRQSLGHGRQGSGSRQSPSHVRHGSGS----------------GHSSSHGQHGSGS 329
Query: 387 APPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPG 446
S + + G G +G G + Q S ++ S + S G
Sbjct: 330 ----------SYSYSRGHYESGSGQTSGFGQHESGSGQ----SSGYSKHGSGSGHSSSQG 375
Query: 447 TPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQG 506
G T G++ S ++ YG + + GS G
Sbjct: 376 QHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGS--------------G 421
Query: 507 RTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQR 566
++PG G + P GQ G PY S + Y
Sbjct: 422 QSPG--HGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVS----------GSGYSSGFGHHE 469
Query: 567 YQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLS 626
+ +G+ S G+ + ER S S S +G+ +L
Sbjct: 470 SSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLG 529
Query: 627 SAVSASGSTSS------QGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVG--SPVGSNQS 678
+ SGS S + + + S + PH S GP S G S +G +S
Sbjct: 530 HSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQES 589
Query: 679 RSGPISPASIPGSQMPPQPPGSQSESSSHPALS-QSPMPQERGFMAGTQR--------NP 729
RSG S GS G S H + S QS + G +G +
Sbjct: 590 RSGQSSGYGQHGSS-----SGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSS 644
Query: 730 QMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYS 789
Q ++YG Q +G SP G SS+ Q S + S GP G+ S +
Sbjct: 645 QSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWS---SSNGPHGSVSGQSSGF 701
Query: 790 GVPSAS-----YSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSS 844
G S S YS G G S+ + HG Q + G S+G+ + G S
Sbjct: 702 GHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHG--SSSGLSSS--YGQHGS 757
Query: 845 MTPSSPGMSQQG-GPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFP--------- 894
+ S G +QG G G P + +++ + S S G +
Sbjct: 758 GSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGF 817
Query: 895 GMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLP 954
G ++SG S YSQ ++S ++Q S + ++S G D S S
Sbjct: 818 GQHESG---SGQGYSQ-HGSASGHFSSQGRHGS-----TSGQSSSSGQHDSSSGQSSSYG 868
Query: 955 LPLKADGKEEGTPQPESKSKDS----YSSQGISQPPTPGNLPVPSPMSPSSASISSFHGD 1010
A G + S S S G Q P+ G S S SS HG
Sbjct: 869 QHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGR----HG- 923
Query: 1011 ESDSISSPGWPKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVS 1070
S S S G+ SS +SS T G R R E+ GS
Sbjct: 924 -SGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR----SEQHGSSSG 978
Query: 1071 SLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQY 1130
S + G+ + + G Q + R G+ S +SS Y Y
Sbjct: 979 SSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH-------GSGSGQSSS----YGPY 1027
Query: 1131 LFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPG 1190
RG S+G ++ + SG G S+ +S
Sbjct: 1028 RSGSGWSSSRGPYESGSGHSSGLGHRE--------SRSGQSSGYGQHGSSSGHS------ 1073
Query: 1191 DLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPD 1250
+ HGQ G+SS+ H S S S + + G S
Sbjct: 1074 ---------STHGQ-HGSTSGQSSSCGQHGASSGQSSS----------HGQHGSGSSQSS 1113
Query: 1251 VMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQ 1310
GR + P G R P + G+ + S +S S G+G+
Sbjct: 1114 GYGRQGSGSGQSPGHGQRGSGSRQSP--SYGRHGSGS-----GRSSSSGQHGSGLGESSG 1166
Query: 1311 FPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHE 1370
F + S + Y Q G G SG +G Q +RH +
Sbjct: 1167 FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS----GQSSRGERH-------GSSSGS 1215
Query: 1371 GDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMM 1430
Y S +Q + +G SG P +G++ G G +HG
Sbjct: 1216 SSHYGQHGSGSRQS--SGHGRQGSGSGHSPSRGRHG--------SGLGHSSSHG----QH 1261
Query: 1431 GGPLQSSSSEGPQQN 1445
G SSS GP ++
Sbjct: 1262 GSGSGRSSSRGPYES 1276
Score = 84.3 bits (207), Expect = 1e-15
Identities = 191/846 (22%), Positives = 277/846 (32%), Gaps = 138/846 (16%)
Query: 74 HPISNNNSLGGAGGGAPQPGPDMEQPQHGGA--------KDSAAGGQADPPGPPLLSKPG 125
H S + G G G QHG A + A+ GQ+ G + G
Sbjct: 1992 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHG-----QHG 2046
Query: 126 DEDDAPPKMGEPAGGRYEHPGLGALGT---QQPPVAVPGGGGGPAAVPE----------- 171
G G + PG G G+ Q P G G G ++
Sbjct: 2047 SGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSG 2106
Query: 172 FNNYYGSAAPASG----GPGGRAGPCFDQHG---GQQSPGMGMMHSASAAAAGAPGSMDP 224
F ++ S+ +S G G + QHG GQ S G S+ +++
Sbjct: 2107 FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGS 2166
Query: 225 LQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAV--- 281
Q+S G S H P R G+G G G G G G +G +V
Sbjct: 2167 RQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQ 2226
Query: 282 --AAAAAAAAAAAGGGGGG-----GYGGSSAGY-----------GVLSSPRQQGGGMMMG 323
+ + ++A + G G G G GS++G G SS Q G G
Sbjct: 2227 HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQS 2286
Query: 324 P-----GGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYG-- 376
G G S S+ GS +G + GQ+ SG + + + S S +G
Sbjct: 2287 SSYGQQGSGSGQSPSRGRHGSGSGHSSSY-GQHGSGSGWSSSSGRH-GSGSGQSSGFGHH 2344
Query: 377 -------GSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAAS 429
Y ++ S S S + + +G ++ G++ + G G + +
Sbjct: 2345 ESSSWQSSGYTQHGSGSGHS---SSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSR 2401
Query: 430 PAWAAAQQRSHPAMSP----GTPGPTMGRSQ-----GSPMDPMVMKRPQLYGMGSNP--- 477
+ Q S SP G G G+S GS + P G G +
Sbjct: 2402 QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLG 2461
Query: 478 --HSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPG--AMAGMQYPQQQMPPQYGQQGV-- 531
S+ QSS Y G +G G G T G + G +GQ G
Sbjct: 2462 HRESRSGQSSGY--GQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGS 2519
Query: 532 ---SGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAP 588
SGY +QG S P Q+ +Q S +G+ S +
Sbjct: 2520 SQSSGYGRQGSGSGQS---------------PGHGQRGSGSRQSPSYGRHGSGSGRSSSS 2564
Query: 589 GKPNHEDLNLIQQERPSSLPDLSG-SIDDLPTGTEATLSSAVSASGSTSSQGDQSNPA-- 645
G + S L + SG + +G ++ S S SG +S G + +
Sbjct: 2565 G------------QHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQ 2612
Query: 646 QSPFSPHASPHLSSIPGGP--SPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSE 703
S H S SS G S S S G S SG GS + Q
Sbjct: 2613 SSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHG 2672
Query: 704 SSSHPALSQSPMPQERGFMA-------GTQRNPQMAQYGPQQTG-PSMSPHPSPGGQMHA 755
S S + S+ P G + G+ + +Q+G S H S GQ
Sbjct: 2673 SGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSST 2732
Query: 756 GISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQG 815
+ S +YG + S Y R A SG S S+ G G G S++ HG G
Sbjct: 2733 FDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSG-QSLSHGRHGSGSGQSSSYGQHGSG 2791
Query: 816 PSQPCG 821
Q G
Sbjct: 2792 SGQSSG 2797
Score = 83.2 bits (204), Expect = 3e-15
Identities = 209/897 (23%), Positives = 303/897 (33%), Gaps = 99/897 (11%)
Query: 176 YGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNS 235
YG S GR G C G QSP G S S ++ N G +
Sbjct: 179 YGEQNSDSHQSSGR-GQCGS--GSGQSPNYGQHGSGSGQSSS---------NDTHGSGSG 226
Query: 236 QCNHYPGY-SRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGG 294
Q + + + S G G G G G S G G G+ +G + G +++ ++++ G
Sbjct: 227 QSSGFSQHKSSSGQSSGYSQHGSGSGHS-SGYGQHGSRSGQSSRGERHRSSSGSSSSYGQ 285
Query: 295 GGGG---GYGGSSAGYGVLSSPRQ----QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRF 347
G G G G G SP G G G G+ S + G G +
Sbjct: 286 HGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQT 345
Query: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407
+G QH SG+ + S + S ++ S S Q ++ ++ G
Sbjct: 346 SGFGQHESGSGQSSGY---SKHGSGSGHSSSQGQHGSTSGQASSSGQ-HGSSSRQSSSYG 401
Query: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467
++A+ G+ + + SP S + S G G GRS S P V
Sbjct: 402 QHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSS--GPYVSGS 459
Query: 468 PQLYGMGSNPHSQPQQSSPYPGGS-------YGPPGPQRYPIGIQGRTPGAMAGMQYPQQ 520
G G + S S GS +G G R +G G+ AG
Sbjct: 460 GYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHG-SRSGQSSRGERQGSSAGSS---- 514
Query: 521 QMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMS--QEGY 578
YGQ G G + S Q P PS+ + +Q S GY
Sbjct: 515 ---SSYGQHGSGSRQSLGHSRHGSGSGQSPS--------PSRGRHESGSRQSSSYGPHGY 563
Query: 579 G---TRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGST 635
G + S+ P G + L QE S G +G +T S SG +
Sbjct: 564 GSGRSSSRGPYESGSGHSSGLG--HQESRSGQSSGYGQ-HGSSSGHSSTHGQHGSTSGQS 620
Query: 636 SSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPP 695
SS G A S S H S GS G + SR S S
Sbjct: 621 SSCGQHG--ATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFG-HSSSYGQ 677
Query: 696 QPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPS-MSPHPSPGGQMH 754
GS SS+ P S S G +G+ ++ +Q+G + S H S GQ
Sbjct: 678 HGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSS 737
Query: 755 AGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQ 814
S S +YG S + R + SG S S G G S+++ HG
Sbjct: 738 RSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSG-HSPSRVRHGSSSGHSSSHGQHGS 796
Query: 815 GP--SQPCGAVPLGRMPSAGM-QNRPFPGNMSSMTPSSPG-MSQQGGPGMGPPMPTV--- 867
G S CG G ++G Q+ G S S+ G S QG G +
Sbjct: 797 GTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQ 856
Query: 868 --NRKAQEAAAAVMQAAANSAQSR------QGSFPGMNQSGLMASSSPYSQPMNNSSSLM 919
+ Q ++ ++A++ A R G PG Q G + SP S + S S
Sbjct: 857 HDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSP-SYGRHGSGSGR 915
Query: 920 NTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSS 979
++ + + + S S G S G+S + + G+ S S + + S
Sbjct: 916 SSSSGRHG------SGSGQSSGFGHKSSSGQS-------SGYTQHGSGSGHSSSYEQHGS 962
Query: 980 QGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSSPKSSSSTTTG 1036
+ G SS S SS+ S S S G + S S S + G
Sbjct: 963 RS-------GQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG 1012
Score = 79.7 bits (195), Expect = 3e-14
Identities = 169/744 (22%), Positives = 246/744 (33%), Gaps = 105/744 (14%)
Query: 100 QHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAV 159
QHG ++ G+ + G + + G+ G + G G G+
Sbjct: 2135 QHGSRSGQSSRGE----------RHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPS 2184
Query: 160 PGGGGGPAAVPEFNNYYGSAAPASGGPG---GRAG--PCFDQH---GGQQSP----GMGM 207
G G + + +GS + S G R+G F QH G S G G
Sbjct: 2185 RGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGS 2244
Query: 208 MHSASAAAAGAPGSMDPL---QNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGG 264
H S G+ + S G +S H G S+ + G G G G G
Sbjct: 2245 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGR 2304
Query: 265 GGGGGGA----GAGGAGAGAVAAAAAAAAAAAGGGGGG----------GYGGSSAGYGVL 310
G G G G G+G+G +++ + + G G GY +G G
Sbjct: 2305 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHS 2364
Query: 311 SSPRQQGGGMMMGPGGG--GAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSP 368
SS Q G G G++S S ++ G G ++ G QH SG+ SP
Sbjct: 2365 SSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQ-------SP 2417
Query: 369 SPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAA 428
SP +G + SS S P +++ G G ++G+G + Q
Sbjct: 2418 SPSRGRHGSGSGQSSSYS----PYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQ---- 2469
Query: 429 SPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYP 488
S + S + + G G T G+S G + S Q SS
Sbjct: 2470 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSC---------------GQHGASSGQSSSH-- 2512
Query: 489 GGSYGPPGPQRYPIGIQGRTPGAMAG--MQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQ 546
G +G Q G QG G G + + P YG+ G G S
Sbjct: 2513 -GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHG------SGSGRSSSSG 2565
Query: 547 PQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSS 606
L + + +S Q S +G+ S G+ + ER S
Sbjct: 2566 QHGSGLGESSGFGHHESSSG----QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGS 2621
Query: 607 LPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPA----QSPFSPHASPHLSSIPG 662
S +G+ + SGS S + + S H S S
Sbjct: 2622 SSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSR 2681
Query: 663 GPSPSPVG--SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG 720
GP S +G S G ++S SG S S GS Q S+S QS + G
Sbjct: 2682 GPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS----GQSSTFDQEG 2737
Query: 721 FMAGTQRNPQMAQYGPQQTGPSMSP----HPSPGGQMHAGISSFQQSNSSGTYGPQMSQY 776
G Q + YG + +G S S H + GQ + S S +YG S
Sbjct: 2738 SSTG-----QSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGS 2792
Query: 777 GPQGNYSRPPAYSGVPSASYSGPG 800
G YS+ + SG SY G
Sbjct: 2793 GQSSGYSQHGSGSGQDGYSYCKGG 2816
Score = 59.7 bits (143), Expect = 3e-08
Identities = 209/926 (22%), Positives = 300/926 (32%), Gaps = 151/926 (16%)
Query: 620 GTEATLSSAVSASGSTSSQGDQ------SNPAQSPFSPHASPHLSSIPGGPSPSPVGSPV 673
G+ + SS GS S Q + S+ + S + H S S+ G S
Sbjct: 248 GSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGS------ 301
Query: 674 GSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQ 733
GS QS S + S G GS S S +S Q GF + Q +
Sbjct: 302 GSRQSPSH-VRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSG 360
Query: 734 YGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGP---QMSQYGPQGNYSRPPAYSG 790
Y +G S H S GQ H S Q++SSG +G Q S YG + SR + G
Sbjct: 361 YSKHGSG---SGHSSSQGQ-HGSTSG--QASSSGQHGSSSRQSSSYGQHESASRHSSGRG 414
Query: 791 VPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSP 850
S+ SG PG HGQ S G+ PS+G F G SS P
Sbjct: 415 QHSSG-SGQSPG---------HGQRGSGS------GQSPSSGQHGTGF-GRSSSSGPYVS 457
Query: 851 GMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQ 910
G G G + + E ++ Q + S S G Q G + S +
Sbjct: 458 GSGYSSGFGH-------HESSSEHSSGYTQHGSGSGHSS-----GHGQHGSRSGQSSRGE 505
Query: 911 PMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPE 970
+S+ ++ S + + S G SP + E G+ Q
Sbjct: 506 RQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGR---------HESGSRQSS 556
Query: 971 SKSKDSYSSQGISQPPTP-----GNLPVPSPMSPSSASISSF--HGDESDSISSPGWPKT 1023
S Y S G S P G+ S S + HG S S+ G +
Sbjct: 557 SYGPHGYGS-GRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGS 615
Query: 1024 PSSPKSSSS---TTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPL 1080
S SS T+G+ + G RY ++GS P+ G+
Sbjct: 616 TSGQSSSCGQHGATSGQSSSH----GQHGSGSSQSSRY----GQQGSGSGQSPSRGRHGS 667
Query: 1081 DLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIER 1140
D + G + N ++ + G + S Y Q+
Sbjct: 668 DFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSS-GFGHKSGSGQSSGYSQH--------GS 718
Query: 1141 GEEPPPEVFSTGDTKKQPKLQPPSPANSG-----SLQGPQTPQSTGSNSMAEVPGDLKPP 1195
G G Q ++SG G + QS+G G
Sbjct: 719 GSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGH---- 774
Query: 1196 TPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRM 1255
+P+ HG + G SS+ H + S S Y+ G G+
Sbjct: 775 SPSRVRHGSSS----GHSSSHGQHGSGTSCSSSC----------GHYESGSGQASGFGQH 820
Query: 1256 PYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGA 1315
+ G + +S F +QG+ ++S QS S + GQ YG
Sbjct: 821 ESGSGQ----GYSQHGSASGHFSSQGRHGSTS-----GQSSSSGQHDSSSGQSSS--YGQ 869
Query: 1316 SYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRH--------MDGMYGPPAK 1367
H G+ G G SGQ P G + Q P+Y RH G +G +
Sbjct: 870 HESASHHASGRGRHGSG--SGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSG 927
Query: 1368 RHEGDMYNMQYSSQQQEMYNQYG------------GSYSGPDRRPIQ-GQYPYPYSRERM 1414
+ G + + SS Q Y Q+G GS SG R Q G S
Sbjct: 928 QSSG--FGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQ 985
Query: 1415 QGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPY-P 1473
G G Q+ G Q G QS S + + ++ PY R G G + PY
Sbjct: 986 HGSGSRQSLG-HGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPY--RSGSGWSSSRGPYES 1042
Query: 1474 GMNRTDDMMVPDQRINHESQWPSHVS 1499
G + + + R S + H S
Sbjct: 1043 GSGHSSGLGHRESRSGQSSGYGQHGS 1068
Score = 59.7 bits (143), Expect = 3e-08
Identities = 101/461 (21%), Positives = 151/461 (32%), Gaps = 34/461 (7%)
Query: 15 GEAPAAPPHQQHHHHHHAHHHHH----HAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQ 70
G + H+ H A+ H H H + Q + F Q+ Q Q
Sbjct: 2219 GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQ 2278
Query: 71 QQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS-KPGDEDD 129
S ++S G G G+ Q P + G S+ G G S + G
Sbjct: 2279 HGSGS-SQSSSYGQQGSGSGQ-SPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 2336
Query: 130 APPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG----- 184
G ++ G G+ + G + +GS++ +S
Sbjct: 2337 QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQH 2396
Query: 185 GPGGRAGPCFDQHG---GQQ-SPGMGMMHSASAAAAG-APGSMDPLQNSHEGYPNSQCNH 239
G G R QHG GQ SP G S S ++ +P +S G S H
Sbjct: 2397 GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGH 2456
Query: 240 YPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGG 299
G + G G G G S G G +G + A++ + G G
Sbjct: 2457 SSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHG 2516
Query: 300 YGGS-SAGYGVLSSPRQQGGGMMMGPGGG--GAASLSKAAAGSAAGGFQRFAGQNQHPSG 356
G S S+GYG +QG G PG G G+ S + G G R + QH SG
Sbjct: 2517 SGSSQSSGYG------RQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSG 2570
Query: 357 ATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMG 416
+S S G YS + S + +G ++ G++ + G
Sbjct: 2571 LGE------SSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSG 2624
Query: 417 LGKDMGAQYAAASPAWAAAQQRSHPAMSP--GTPGPTMGRS 455
G + + + +Q S SP G G +G S
Sbjct: 2625 SSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHS 2665
Score = 49.7 bits (117), Expect = 3e-05
Identities = 84/399 (21%), Positives = 128/399 (32%), Gaps = 67/399 (16%)
Query: 24 QQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLG 83
Q + H H + H H Q + Q Q Q S+
Sbjct: 2469 QSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ 2528
Query: 84 GAGGG-APQPGP----DMEQPQHG----GAKDSAAGGQADPPGPPLLSKPG-----DEDD 129
G+G G +P G + P +G G+ S++ GQ G L G
Sbjct: 2529 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH---GSGLGESSGFGHHESSSG 2585
Query: 130 APPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGR 189
+ G G G G++ + G + +GS + S G G R
Sbjct: 2586 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHG-R 2644
Query: 190 AGPCFDQHGGQQSPGMGMMHSAS----AAAAGAPGSMDPLQN-----SHEGYPNSQCNHY 240
G Q + G G+ HS+S + +G S P ++ S G S H
Sbjct: 2645 QGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHS 2704
Query: 241 PGYSRPGAGGG--------GGGGGGG------GGGSGGGGGGGGAGAGGAGAGAVAAAAA 286
YS+ G+G G G G G +G G G+G + + A
Sbjct: 2705 SAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGA 2764
Query: 287 AAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQR 346
+ + G G G S+ YG G G G ++ S+ +GS G+
Sbjct: 2765 GSGQSLSHGRHGSGSGQSSSYG------------QHGSGSGQSSGYSQHGSGSGQDGYSY 2812
Query: 347 FAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSP 385
G + H G++ SY S+P +SP
Sbjct: 2813 CKGGSNHDGGSS--------------GSYFLSFPSSTSP 2837
Score = 43.9 bits (102), Expect = 0.002
Identities = 81/328 (24%), Positives = 110/328 (33%), Gaps = 59/328 (17%)
Query: 1166 ANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDV 1225
++S G + QS G G + P+P+ HG + G+SS+ S + S
Sbjct: 2390 SSSYGQHGSGSRQSLGHGQHGSGSG--QSPSPSRGRHGSGS----GQSSSYSPYGSGSGW 2443
Query: 1226 SDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPN 1285
S S PY+ G +G E G + SS T GQ +
Sbjct: 2444 SSS----------RGPYESGSGHSSGLGHR--ESRSGQSSGYGQHGSSSGHSSTHGQHGS 2491
Query: 1286 SSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQP 1345
+S QS S GQ S + YG+Q G SGQ P G +
Sbjct: 2492 TS-----GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ----GSGSGQSPGHGQRG 2542
Query: 1346 GLYPQQPNYKRHMDGMYGPPAKRHEGD-------MYNMQYSSQQQEMYNQYG-------- 1390
Q P+Y RH G + G + + SS Q Y+Q+G
Sbjct: 2543 SGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSG 2602
Query: 1391 ----GSYSGPDRR-PIQGQYPYPYSRERMQGPGQIQTHGIPPQ-----------MMGGPL 1434
GS SG R G S G G Q+ G Q G L
Sbjct: 2603 YGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGL 2662
Query: 1435 QSSSSEGPQQNMWAARNDMPYPYQNRQG 1462
SSS G Q + R+ PY++R G
Sbjct: 2663 GHSSSHG-QHGSGSGRSSSRGPYESRLG 2689
>gi|48762934 alpha 2 type I collagen [Homo sapiens]
Length = 1366
Score = 111 bits (277), Expect = 9e-24
Identities = 210/819 (25%), Positives = 270/819 (32%), Gaps = 125/819 (15%)
Query: 77 SNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPP-LLSKPGDE-----DDA 130
S N G+ G PGP E+ + G + G A PPGPP L PG D
Sbjct: 357 SGNKGEPGSAGPQGPPGPSGEEGKRG---PNGEAGSAGPPGPPGLRGSPGSRGLPGADGR 413
Query: 131 PPKMGEPA----------------GGRYEHPGL-GALGTQQPPVAV-PGGGGGPAAVPEF 172
MG P GR PGL G G P + P G GP +P
Sbjct: 414 AGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGI 473
Query: 173 NNYYGSAAPAS--GGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHE 230
+ G PA G PG P G H+ A A GAPG N +
Sbjct: 474 DGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDG--NNGAQ 531
Query: 231 GYPNSQ----------------CNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAG 274
G P Q PG S P G G G G G G G G
Sbjct: 532 GPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGER 591
Query: 275 GAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMG-PGGGGAASLS 333
G + AA + G G G G+ GV+ + G G PG GAA +
Sbjct: 592 GPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIP 651
Query: 334 KAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPP-- 391
G + G N GA + +P P + + P+ P P
Sbjct: 652 GGKGEKGEPGLRGEIG-NPGRDGARGAPG-AVGAPGPAGATGDRGEAGAAGPAGPAGPRG 709
Query: 392 ---------PSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPA 442
P+ P A AGAA GQ A G K + P + PA
Sbjct: 710 SPGERGEVGPAGPNGFAGPAGAA--GQPGAKGERGAKGPKGENGVVGPTGPVG--AAGPA 765
Query: 443 MSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPI 502
G PGP R G P GM P + + P P G GPPGP P
Sbjct: 766 GPNGPPGPAGSRGDGGPP-----------GMTGFPGAAGRTGPPGPSGISGPPGPPG-PA 813
Query: 503 GIQG-RTPGAMAGMQYPQQQM----PPQY-GQQGVSGYCQQGQQPYYSQQPQPPHLPPQA 556
G +G R P G ++ PP + G++G SG P + PQ P
Sbjct: 814 GKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPP-GTPGPQGLLGAPGI 872
Query: 557 QYLPSQSQQRYQP--QQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSI 614
LP +R P + + G + PP A G P P ++G+
Sbjct: 873 LGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPG-----------AVGSPGVNGA- 920
Query: 615 DDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSP-SPVGSPV 673
EA G G + + + + P G P P PVG P
Sbjct: 921 -----PGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGP--VGAAGAPGPHGPVG-PA 972
Query: 674 GSNQSR-----SGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRN 728
G + +R SGP+ PA G + P P G + + +P +G G Q
Sbjct: 973 GKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGH-NGLQGL 1031
Query: 729 PQMA-----QYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNY- 782
P +A Q P GP+ P G AG ++ GT GP + GPQG+
Sbjct: 1032 PGIAGHHGDQGAPGSVGPA-GPRGPAGPSGPAGKDG--RTGHPGTVGPAGIR-GPQGHQG 1087
Query: 783 -SRPPAYSGVPS-ASYSGPGPGMGISANNQMHGQGPSQP 819
+ PP G P SG G G + Q S P
Sbjct: 1088 PAGPPGPPGPPGPPGVSGGGYDFGYDGDFYRADQPRSAP 1126
Score = 107 bits (268), Expect = 1e-22
Identities = 219/926 (23%), Positives = 286/926 (30%), Gaps = 173/926 (18%)
Query: 87 GGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPG 146
G A GP E+ G G PPGPP PG PP +G +Y+ G
Sbjct: 33 GPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPP--GPPG-----PPGLGGNFAAQYDGKG 85
Query: 147 LGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA----PASGGPGGRAGPCFDQHGGQQS 202
+G LG + P G G A P + G A P GP G GP G
Sbjct: 86 VG-LGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGP-----AGPPG 139
Query: 203 PGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGS 262
H G G + P G+P + PG+ G G G G
Sbjct: 140 KAGEDGHPGKPGRPGERGVVGP--QGARGFPGTP--GLPGFKGIRGHNGLDGLKGQPGAP 195
Query: 263 GGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMM 322
G G G G G A G G G GS G + G
Sbjct: 196 GVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSA--- 252
Query: 323 GPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEY 382
GP G A K G+ N P+G ++ P
Sbjct: 253 GPPGFPGAPGPKGEIGAVG---------NAGPAGPAGPRGEV-------------GLPGL 290
Query: 383 SSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGM----------GLGKDMGAQYAAASPAW 432
S P PP P A A G A G+ G GA+ P
Sbjct: 291 SGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGP 350
Query: 433 AAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPY-PGGS 491
A ++ S PG+ GP QG P P + + P GS
Sbjct: 351 AGSKGESGNKGEPGSAGP-----QGPP----------------GPSGEEGKRGPNGEAGS 389
Query: 492 YGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPH 551
GPPGP G++G +PG+ + +P G+ GV G
Sbjct: 390 AGPPGPP----GLRG-SPGS--------RGLPGADGRAGVMG------------------ 418
Query: 552 LPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLS 611
PP ++ + R P D + G P PG P ++ +E P LP +
Sbjct: 419 -PPGSRGASGPAGVR-GPNGDAGRPGEPGLMGPRGLPGSPG--NIGPAGKEGPVGLPGID 474
Query: 612 GSIDDL-PTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVG 670
G + P G + G +G +P ++ HA L+ G P P
Sbjct: 475 GRPGPIGPAGARGEPGNI----GFPGPKGPTGDPGKNGDKGHAG--LAGARGAPGPD--- 525
Query: 671 SPVGSNQSRSGPISPASI---PGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQR 727
N GP P + G Q PP PPG Q + P ERG
Sbjct: 526 ----GNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGL------ 575
Query: 728 NPQMAQYG-PQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPP 786
++G P GP P PG AG + S G GP GP GN P
Sbjct: 576 ---HGEFGLPGPAGPRGERGP-PGESGAAGPTG--PIGSRGPSGPP----GPDGNKGEPG 625
Query: 787 AYSGVPSASYSGPG--PGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQN-RPFPGNMS 843
V +A SGP PG A G+G G G + + G R PG +
Sbjct: 626 VVGAVGTAGPSGPSGLPGER-GAAGIPGGKGEKGEPGL--RGEIGNPGRDGARGAPGAVG 682
Query: 844 SMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMA 903
+ P+ + GP P R + V A N G+ G
Sbjct: 683 APGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERG 742
Query: 904 SSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVG-LADMMSPGESKLPLPLKADGK 962
+ P + ++ P + PA N G D PG + P A G+
Sbjct: 743 AKGP-----KGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFP---GAAGR 794
Query: 963 EEGTPQPESKSKDSYSSQGISQPPTP 988
G P P GIS PP P
Sbjct: 795 -TGPPGP----------SGISGPPGP 809
Score = 53.9 bits (128), Expect = 2e-06
Identities = 82/294 (27%), Positives = 101/294 (34%), Gaps = 62/294 (21%)
Query: 73 QHPISNNNSLGGAG--GGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDA 130
Q P+ +G G G A + GP S G A PPG P P A
Sbjct: 825 QGPVGRTGEVGAVGPPGFAGEKGP------------SGEAGTAGPPGTP---GPQGLLGA 869
Query: 131 PPKMGEPAGGRYEH--PGLGALGTQQPPVAV---PGGGGGPAAV--PEFNNYYGSAA--- 180
P +G P G R E PG+ + P+ + PG G P AV P N G A
Sbjct: 870 PGILGLP-GSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDG 928
Query: 181 -PASGGPGGRAGPCFDQHGGQQS-PGMGMMHSASAAAAGAPGSMDPLQ------NSHEGY 232
P + GP GR G H G++ PG + AAGAPG P+ N E
Sbjct: 929 NPGNDGPPGRDGQ--PGHKGERGYPG----NIGPVGAAGAPGPHGPVGPAGKHGNRGETG 982
Query: 233 PNSQCNHY--------------------PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAG 272
P+ PG P G G G G G G G G
Sbjct: 983 PSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQG 1042
Query: 273 AGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGG 326
A G+ A A + AG G G+ G+ G+ QG GP G
Sbjct: 1043 APGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPG 1096
Score = 49.3 bits (116), Expect = 4e-05
Identities = 99/395 (25%), Positives = 134/395 (33%), Gaps = 65/395 (16%)
Query: 679 RSGPISPASIPGSQMPPQPPGSQSES--SSHPALSQSPMPQERGFMAGTQRNPQMAQYGP 736
R GP G + PP PPG E + P P P G Q + + GP
Sbjct: 31 RKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGP 90
Query: 737 QQTGPSMSPHPSPGGQMHAGISSFQ----------QSNSSGTYGPQ--MSQYGPQGNYSR 784
G M P PG G FQ Q+ +G GP + G G+ +
Sbjct: 91 GPMG-LMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGK 149
Query: 785 P--PAYSGV--PSASYSGPG-PGM----GISANNQMHGQGPSQPCGAVPLGRMPSAGMQN 835
P P GV P + PG PG+ GI +N + G QP GA + P A +N
Sbjct: 150 PGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGL-KGQP-GAPGVKGEPGAPGEN 207
Query: 836 RPFPGNMSSMTPSSPGMSQQGGPG----MGPPMPTVNRKAQEAAAAVMQAAANSAQSRQG 891
TP G +G PG +G P P R + + V A + G
Sbjct: 208 G---------TPGQTGA--RGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPG 256
Query: 892 SFPGM----NQSGLMASSSPYSQPMNNSS----SLMNTQAPPYSMAPAMVNSSAASVGLA 943
FPG + G + ++ P L PP + + + + GL
Sbjct: 257 -FPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLP 315
Query: 944 DMMS----PGESKLPLPLKADGKEE-----GTPQPESKSKDSYSSQGISQPPTPGNLPVP 994
+ PG +P P+ A G G P P SK ++G PG+
Sbjct: 316 GVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAG-SKGESGNKG-----EPGSAGPQ 369
Query: 995 SPMSPSSASISSFHGDESDSISSPGWPKTPSSPKS 1029
P PS E+ S PG P SP S
Sbjct: 370 GPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGS 404
>gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein [Homo
sapiens]
Length = 593
Score = 111 bits (277), Expect = 9e-24
Identities = 101/362 (27%), Positives = 160/362 (44%), Gaps = 49/362 (13%)
Query: 850 PGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYS 909
PG ++ P ++AQ AA A M+AAA A + PG ++ G
Sbjct: 36 PGRARAAPDEDREPESARMQRAQMAALAAMRAAA--AGLGHPASPGGSEDG--------- 84
Query: 910 QPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQP 969
P + + P S P DM S + K + + EE +
Sbjct: 85 -PPGSEEEDAAREGTPGS--PGRGREGPGEEHFEDMASDEDMKPKW--EEEEMEEDLGED 139
Query: 970 ESKSKDSYSSQGISQ------PPTPGNLPVPSPMSPSSASISSFHGDESDSI------SS 1017
E + ++ Y + + PP P +L + + +F GD +
Sbjct: 140 EEEEEEDYEDEEEEEDEEGLGPPGPASLGTTALFPRKAQPPQAFRGDGVPRVLGGQERPG 199
Query: 1018 PGWPKTPSS---------PKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSP 1068
PG P P P T E+ ++YEL +P+RK ++D +FM++RG+P
Sbjct: 200 PG-PAHPGGAAHVAPQLQPPDHGDWTYEEQFKQLYELDGDPKRKEFLDDLFSFMQKRGTP 258
Query: 1069 VSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTS-SSAASSLKKQY 1127
V+ +P + K+ LDLF LYV V E GGL +V K WRE+ LN+ TS +SAA +L+ QY
Sbjct: 259 VNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQY 318
Query: 1128 IQYLFAFECKIERGEEPPPEVFSTGDTKKQP--------KLQPPSPANS-GSLQGPQTPQ 1178
++YL+ +EC+ +RG P E+ + D+ ++ L SP + G L P+ P
Sbjct: 319 MKYLYPYECE-KRGLSNPNELQAAIDSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPV 377
Query: 1179 ST 1180
S+
Sbjct: 378 SS 379
Score = 40.0 bits (92), Expect = 0.026
Identities = 18/51 (35%), Positives = 23/51 (45%)
Query: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAA 291
P P + GGGGGGG S GG GG G G AG + + + +
Sbjct: 538 PPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTS 588
Score = 37.0 bits (84), Expect = 0.22
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 8/93 (8%)
Query: 1686 GDPSQKALDHNAARKDDSQSLADDSG-----KEEEDAECIDDDEEDEEDEEEDSEKTESD 1740
G P ++ + +A D +EEE E + +DEE+EE++ ED E+ E +
Sbjct: 97 GTPGSPGRGREGPGEEHFEDMASDEDMKPKWEEEEMEEDLGEDEEEEEEDYEDEEEEEDE 156
Query: 1741 E---KSSIALTAPDAAADPKEKPKQASKFDKLP 1770
E A A K +P QA + D +P
Sbjct: 157 EGLGPPGPASLGTTALFPRKAQPPQAFRGDGVP 189
Score = 33.9 bits (76), Expect = 1.8
Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 1/98 (1%)
Query: 59 QQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSA-AGGQADPPG 117
Q+QQ+ +Q+ + +QQ P + G AP + E + A+ +A A +A G
Sbjct: 12 QRQQRARQELEARQQLPPDPPAAPPGRARAAPDEDREPESARMQRAQMAALAAMRAAAAG 71
Query: 118 PPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQP 155
+ PG +D PP E R PG G + P
Sbjct: 72 LGHPASPGGSEDGPPGSEEEDAAREGTPGSPGRGREGP 109
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 107 bits (268), Expect = 1e-22
Identities = 167/687 (24%), Positives = 228/687 (33%), Gaps = 128/687 (18%)
Query: 374 SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWA 433
S G + P Y P PP P P S A+ + G M + A
Sbjct: 152 SQGPARP-YHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPP 210
Query: 434 AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYG 493
A HP + PG G G G PM P G + P ++P S G
Sbjct: 211 GAPP-PHPQLYPGGTG---GVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSG 266
Query: 494 PPG-----PQRYPIGIQGRTPGAMAGMQYPQ--QQMPPQYGQQGVSGYCQQGQQPYYSQQ 546
G P P+G G P A +P +PP + ++ P Q
Sbjct: 267 ASGAPPTKPPTTPVG-GGNLPSAPPPANFPHVTPNLPPPPALRPLNN--ASASPPGLGAQ 323
Query: 547 PQPPHLP-PQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPS 605
P P HLP P A Q M G P LAP P
Sbjct: 324 PLPGHLPSPHAM------------GQGMGGLPPGPEKGPTLAPS--------------PH 357
Query: 606 SLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFS------PHASPHLSS 659
SLP S S P + SS+ SA+ S+SS S+ + P S PH+ P +S
Sbjct: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417
Query: 660 IP---------------------GGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPP 698
+ G P P P G + ++ + GP P++ G+Q PP
Sbjct: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPST--GAQSTAHPP 475
Query: 699 GSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGIS 758
S+ H Q Q++ Q+ GP P PHP GG H
Sbjct: 476 ----VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP--PGAFPHPLEGGSSHHA-H 528
Query: 759 SFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGP-GPGMGISANNQMHGQGPS 817
+ S S G+ P P G PP +S V S S +GP GP + S+N+ S
Sbjct: 529 PYAMSPSLGSLRPY-----PPGPAHLPPPHSQV-SYSQAGPNGPPVSSSSNSSSSTSQGS 582
Query: 818 QPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAA 877
PC + SP QG P PP+PTV + +
Sbjct: 583 YPC-------------------------SHPSPSQGPQGAPYPFPPVPTVTTSSATLSTV 617
Query: 878 VMQAAANSAQSRQGSFPGMNQSGLMASS------------SPYSQPMNNSSSLMNTQAPP 925
+ A++ A + S PG G A S P S P + + +
Sbjct: 618 IATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTS 677
Query: 926 YSMAPAMVNSSAASVGLADMMSPGESKLP-LPLKADGKEEGTP----QPESKSKDSYSSQ 980
P + +VG + G S LP LP G P Q + + + Y +
Sbjct: 678 PPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETP 737
Query: 981 GISQPPTPGNLPVPSPMS-PSSASISS 1006
PP P P + PS AS S+
Sbjct: 738 ESPVPPARSPSPPPKVVDVPSHASQSA 764
Score = 81.6 bits (200), Expect = 8e-15
Identities = 156/668 (23%), Positives = 200/668 (29%), Gaps = 112/668 (16%)
Query: 106 DSAAG---GQADPPGPPLLSKPGDED-DAPPKMGEPAGGRYEHPGLGALGTQQP------ 155
DS++G G A P PP L P + D+ P+ +P HP + G P
Sbjct: 146 DSSSGLSQGPARPYHPPPLFPPSPQPPDSTPR--QPEASFEPHPSVTPTGYHAPMEPPTS 203
Query: 156 -------------PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQS 202
P PGG GG + P G AA + GGP G G Q
Sbjct: 204 RMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNG---------GKQHP 254
Query: 203 PGMGMMHSASAAAAGAPGSMDPLQ-----NSHEGYPNSQCNHY-PGYSRPGAGGGGGGGG 256
P + +S+ A+GAP + P N P + H P P A
Sbjct: 255 PPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPA-------- 306
Query: 257 GGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY-GGSSAGYGVLSSPRQ 315
A A G GA + A G G GG G G + SP
Sbjct: 307 --------LRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS 358
Query: 316 QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATP-TLNQLLTS-----PS 369
P S +++ SAA + + S A+P +Q L S P
Sbjct: 359 LPPASSSAPAPPMRFPYSSSSSSSAAAS----SSSSSSSSSASPFPASQALPSYPHSFPP 414
Query: 370 PMMRSYGGSYPEYSSPSAPP-------PPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMG 422
P S P+Y+ PS P PPP P + A A G G
Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGP-------FPPSTG 467
Query: 423 AQYAAASPAWA-----AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP 477
AQ A P QQ+ P P P L G GS+
Sbjct: 468 AQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP-LEG-GSSH 525
Query: 478 HSQPQQSSPYPGGSYG-PPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQ 536
H+ P SP G PPGP P P + PP S
Sbjct: 526 HAHPYAMSPSLGSLRPYPPGPAHLP------PPHSQVSYSQAGPNGPPVSSSSNSSSSTS 579
Query: 537 QGQQPYYSQQPQPPHLPPQAQY---------LPSQSQQRYQPQQDMSQEGYGTRSQPPLA 587
QG P P P P A Y S + S GY T S P
Sbjct: 580 QGSYP--CSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPP 637
Query: 588 PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQS 647
P + P GS TGT +G + +
Sbjct: 638 PYGKRAPSPGAYKTATPPGYK--PGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPG 695
Query: 648 PFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMP----PQPPGSQSE 703
P P L S+P P+ G P+ + Q + P P S +P P PP +
Sbjct: 696 PLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVD 755
Query: 704 SSSHPALS 711
SH + S
Sbjct: 756 VPSHASQS 763
Score = 80.9 bits (198), Expect = 1e-14
Identities = 144/602 (23%), Positives = 196/602 (32%), Gaps = 97/602 (16%)
Query: 251 GGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVL 310
GG GG G G GGG + GG G + + G G V
Sbjct: 222 GGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPV- 280
Query: 311 SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSP 370
GG + P ++ A A + GA P L L SP
Sbjct: 281 -----GGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQP-LPGHLPSPHA 334
Query: 371 MMRSYGGSYP-EYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAAS 429
M + GG P P+ P P S P + ++A M Y+++S
Sbjct: 335 MGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAP---------------APPMRFPYSSSS 379
Query: 430 PAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPG 489
+ AAA S + S +P P SQ P P P + + P Q S P
Sbjct: 380 SSSAAASSSSSSSSSSASPFPA---SQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQA 436
Query: 490 -GSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQ 548
S GPP P Y GR +A PP G Q +
Sbjct: 437 VWSQGPPPPPPY-----GR---LLANSNAHPGPFPPSTGAQSTA---------------H 473
Query: 549 PPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLP 608
PP + Q QQ+ Q QQ Q+ + S PP P+ + P ++
Sbjct: 474 PPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMS 533
Query: 609 DLSGSIDDLPTG--------TEATLSSA-------VSASGSTSSQGDQSNPAQSPFSPHA 653
GS+ P G ++ + S A S+S S+SS S P P SP
Sbjct: 534 PSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP-SPSQ 592
Query: 654 SPHLSSIPGGPSPSPVGSPVGSNQSRSGPISP-----ASIPGSQMPPQPPGSQSESSSHP 708
P G P P P PV + + S +S AS P PPG P
Sbjct: 593 GPQ-----GAPYPFP---PVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP 644
Query: 709 ALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGT 768
+ G+ G +P + G SP PG +F+ + +
Sbjct: 645 SPGAYKTATPPGYKPG---SPPSFRTGTPPGYRGTSPPAGPG--------TFKPGSPTVG 693
Query: 769 YGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRM 828
GP + GP G S PP P+A S GP + + Q + P VP R
Sbjct: 694 PGP-LPPAGPSGLPSLPPP----PAAPAS--GPPLSATQIKQEPAEEYETPESPVPPARS 746
Query: 829 PS 830
PS
Sbjct: 747 PS 748
Score = 77.0 bits (188), Expect = 2e-13
Identities = 188/853 (22%), Positives = 276/853 (32%), Gaps = 194/853 (22%)
Query: 841 NMSSMTPSSPGMSQQGGP-----GMGPPMPT-VNRKAQEAAAAVMQAAANSAQSRQGSFP 894
N SM+ S + GP G P V+ + + A + A A+ + S P
Sbjct: 6 NKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTP 65
Query: 895 GMNQSGLMAS-SSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKL 953
+N+ G S S+ N Q P +P+ ++S ++ S
Sbjct: 66 KVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGR-----SLNDDGSSD 120
Query: 954 PLPLKADGKEEGTP--QPESKSKDSYSSQGISQPPT----PGNLPVPSPMSPSSASISSF 1007
P + D + P S DS SS G+SQ P P L PSP P S
Sbjct: 121 PRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDS------ 174
Query: 1008 HGDESDSISSPGWPKTPSSPKSS-----SSTTTGEKITKVYELGNEPERKLWVDRYLTFM 1062
TP P++S S T TG Y EP F
Sbjct: 175 ---------------TPRQPEASFEPHPSVTPTG------YHAPMEPPTSRM------FQ 207
Query: 1063 EERGSP-------------VSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELAT 1109
G+P V S P +G K +GG N K+ T
Sbjct: 208 APPGAPPPHPQLYPGGTGGVLSGPPMGPKGGG------AASSVGG---PNGGKQHPPPTT 258
Query: 1110 NLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPS---PA 1166
++V +S ++ + K + PPP F P L PP P
Sbjct: 259 PISVSSSGASGAPPTKPPTTPVGGGNLP----SAPPPANFP----HVTPNLPPPPALRPL 310
Query: 1167 NSGSLQGP-----------QTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSST 1215
N+ S P +P + G PG K PT A +PH P +
Sbjct: 311 NNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS--LPPASSSAPA 368
Query: 1216 ISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSE 1275
+ P+S S SS +S + ++ + PF + +P
Sbjct: 369 PPMRFPYSSSSSSSAAASSSSSSSSS------------------SASPFPASQALPSYPH 410
Query: 1276 PFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPS 1335
F + S+ Y Q + + G PYG R +PG PPS
Sbjct: 411 SFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYG-----RLLANSNAHPGPFPPS 465
Query: 1336 GQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSG 1395
G Q +P + H H+ Q QQQ+ Q+ G+ SG
Sbjct: 466 T-----GAQSTAHPPVSTHHHH-----------HQQQQQQQQQQQQQQQQQQQHHGN-SG 508
Query: 1396 PDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPY 1455
P P G +P+P ++G H P S S G + +P
Sbjct: 509 P---PPPGAFPHP-----LEGGSSHHAH---------PYAMSPSLGSLRPYPPGPAHLPP 551
Query: 1456 PYQ----NRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPY------- 1504
P+ ++ GP GP P N + +H S PS Q PY
Sbjct: 552 PHSQVSYSQAGPNGP---PVSSSSNSSSSTSQGSYPCSHPS--PSQGPQGAPYPFPPVPT 606
Query: 1505 -MSSSASMQPI-----TRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLP 1558
+SSA++ + + P +PP P + RAPSP +++ + P P
Sbjct: 607 VTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFR 666
Query: 1559 SMKMQKVMPTVPT---------SQVTGPPPQPP--PIRREITFPPGSVEASQPVLK--QR 1605
+ T P S GP P PP P PP + AS P L Q
Sbjct: 667 TGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQI 726
Query: 1606 RKITSKDIVTPEA 1618
++ +++ TPE+
Sbjct: 727 KQEPAEEYETPES 739
Score = 62.4 bits (150), Expect = 5e-09
Identities = 73/279 (26%), Positives = 92/279 (32%), Gaps = 67/279 (24%)
Query: 13 TVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQ 72
+ G A P HHHHH QQQQQQQQQQQQQQQQQ
Sbjct: 465 STGAQSTAHPPVSTHHHHHQ-----------------------QQQQQQQQQQQQQQQQQ 501
Query: 73 QHPISNNNSLGGA------GGGAPQPGPDMEQPQHGGAKDSAAG-------------GQA 113
QH ++ GA GG + P P G + G QA
Sbjct: 502 QHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQA 561
Query: 114 DPPGPPLLSKPGDEDDA---------PPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGG 164
P GPP+ S P P G Y P + + T ++
Sbjct: 562 GPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTV---- 617
Query: 165 GPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDP 224
A V Y +A+P P G+ P SPG + G+P S
Sbjct: 618 -IATVASSPAGYKTASPPGPPPYGKRAP---------SPGAYKTATPPGYKPGSPPSF-- 665
Query: 225 LQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSG 263
+ GY + PG +PG+ G G G SG
Sbjct: 666 RTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG 704
Score = 52.0 bits (123), Expect = 7e-06
Identities = 160/727 (22%), Positives = 241/727 (33%), Gaps = 152/727 (20%)
Query: 635 TSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMP 694
+ S+ +++N +P + +P SPS + S G + + G P I
Sbjct: 77 SESESEETN------APKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRS 130
Query: 695 PQP----PGS-QSESSSHPALSQSPMPQERGFMAGT--QRNPQMAQYGPQQTGPSMSPHP 747
P PGS +++S S LSQ P R + +PQ P+Q S PHP
Sbjct: 131 TSPSIYSPGSVENDSDSSSGLSQGPA---RPYHPPPLFPPSPQPPDSTPRQPEASFEPHP 187
Query: 748 SPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISA 807
S G + + +S +M Q P P Y G SGP G
Sbjct: 188 SV---TPTGYHAPMEPPTS-----RMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGP---- 235
Query: 808 NNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTV 867
G G + G P+ G Q+ P + ++ SS G S G P PP V
Sbjct: 236 ----KGGGAASSVGG------PNGGKQHPP---PTTPISVSSSGAS--GAPPTKPPTTPV 280
Query: 868 NRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYS 927
+ P + P N + PP +
Sbjct: 281 G----------------------------------GGNLPSAPPPANFPHVTPNLPPPPA 306
Query: 928 MAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPT 987
+ P + N+SA+ GL PG LP P A G+ G P + + + S PP
Sbjct: 307 LRP-LNNASASPPGLGAQPLPGH--LPSP-HAMGQGMGGLPPGPEKGPTLAPSPHSLPPA 362
Query: 988 PGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSSPKSSSSTTTGEKITKVYELGN 1047
+ P P P S+S SS S S SS SS+S + Y
Sbjct: 363 SSSAPAPPMRFPYSSSSSSSAAASSSS----------SSSSSSASPFPASQALPSYPHSF 412
Query: 1048 EPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWREL 1107
P L V + P ++ + G P + G N N
Sbjct: 413 PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPY----------GRLLANSNAHPGPF 462
Query: 1108 ATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPAN 1167
+ G S+A + + + + + ++ ++ + G++ P P P
Sbjct: 463 PP--STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLE 520
Query: 1168 SGSLQGPQTPQSTGSNSMAEVPGDLK--PPTPA--STPHGQMTPMQGGRSSTISVHDPFS 1223
GS +M+ G L+ PP PA PH Q++ Q G + P S
Sbjct: 521 GGS------SHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNG-----PPVS 569
Query: 1224 DVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQM 1283
S+SS S T Y S P P++ P G P P +T
Sbjct: 570 SSSNSS-----SSTSQGSYP--CSHP--------SPSQGPQGA--PYPFPPVPTVTTSSA 612
Query: 1284 PNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGP-PSGQPPYGG 1342
S++ SP+G Y + PYG++ P G + PP G
Sbjct: 613 TLSTVIATVASSPAG--------------YKTASPPGPPPYGKRAPSPGAYKTATPP--G 656
Query: 1343 HQPGLYP 1349
++PG P
Sbjct: 657 YKPGSPP 663
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 107 bits (268), Expect = 1e-22
Identities = 167/687 (24%), Positives = 228/687 (33%), Gaps = 128/687 (18%)
Query: 374 SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWA 433
S G + P Y P PP P P S A+ + G M + A
Sbjct: 152 SQGPARP-YHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPP 210
Query: 434 AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYG 493
A HP + PG G G G PM P G + P ++P S G
Sbjct: 211 GAPP-PHPQLYPGGTG---GVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSG 266
Query: 494 PPG-----PQRYPIGIQGRTPGAMAGMQYPQ--QQMPPQYGQQGVSGYCQQGQQPYYSQQ 546
G P P+G G P A +P +PP + ++ P Q
Sbjct: 267 ASGAPPTKPPTTPVG-GGNLPSAPPPANFPHVTPNLPPPPALRPLNN--ASASPPGLGAQ 323
Query: 547 PQPPHLP-PQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPS 605
P P HLP P A Q M G P LAP P
Sbjct: 324 PLPGHLPSPHAM------------GQGMGGLPPGPEKGPTLAPS--------------PH 357
Query: 606 SLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFS------PHASPHLSS 659
SLP S S P + SS+ SA+ S+SS S+ + P S PH+ P +S
Sbjct: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417
Query: 660 IP---------------------GGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPP 698
+ G P P P G + ++ + GP P++ G+Q PP
Sbjct: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPST--GAQSTAHPP 475
Query: 699 GSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGIS 758
S+ H Q Q++ Q+ GP P PHP GG H
Sbjct: 476 ----VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP--PGAFPHPLEGGSSHHA-H 528
Query: 759 SFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGP-GPGMGISANNQMHGQGPS 817
+ S S G+ P P G PP +S V S S +GP GP + S+N+ S
Sbjct: 529 PYAMSPSLGSLRPY-----PPGPAHLPPPHSQV-SYSQAGPNGPPVSSSSNSSSSTSQGS 582
Query: 818 QPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAA 877
PC + SP QG P PP+PTV + +
Sbjct: 583 YPC-------------------------SHPSPSQGPQGAPYPFPPVPTVTTSSATLSTV 617
Query: 878 VMQAAANSAQSRQGSFPGMNQSGLMASS------------SPYSQPMNNSSSLMNTQAPP 925
+ A++ A + S PG G A S P S P + + +
Sbjct: 618 IATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTS 677
Query: 926 YSMAPAMVNSSAASVGLADMMSPGESKLP-LPLKADGKEEGTP----QPESKSKDSYSSQ 980
P + +VG + G S LP LP G P Q + + + Y +
Sbjct: 678 PPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETP 737
Query: 981 GISQPPTPGNLPVPSPMS-PSSASISS 1006
PP P P + PS AS S+
Sbjct: 738 ESPVPPARSPSPPPKVVDVPSHASQSA 764
Score = 81.6 bits (200), Expect = 8e-15
Identities = 156/668 (23%), Positives = 200/668 (29%), Gaps = 112/668 (16%)
Query: 106 DSAAG---GQADPPGPPLLSKPGDED-DAPPKMGEPAGGRYEHPGLGALGTQQP------ 155
DS++G G A P PP L P + D+ P+ +P HP + G P
Sbjct: 146 DSSSGLSQGPARPYHPPPLFPPSPQPPDSTPR--QPEASFEPHPSVTPTGYHAPMEPPTS 203
Query: 156 -------------PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQS 202
P PGG GG + P G AA + GGP G G Q
Sbjct: 204 RMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNG---------GKQHP 254
Query: 203 PGMGMMHSASAAAAGAPGSMDPLQ-----NSHEGYPNSQCNHY-PGYSRPGAGGGGGGGG 256
P + +S+ A+GAP + P N P + H P P A
Sbjct: 255 PPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPA-------- 306
Query: 257 GGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY-GGSSAGYGVLSSPRQ 315
A A G GA + A G G GG G G + SP
Sbjct: 307 --------LRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS 358
Query: 316 QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATP-TLNQLLTS-----PS 369
P S +++ SAA + + S A+P +Q L S P
Sbjct: 359 LPPASSSAPAPPMRFPYSSSSSSSAAAS----SSSSSSSSSASPFPASQALPSYPHSFPP 414
Query: 370 PMMRSYGGSYPEYSSPSAPP-------PPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMG 422
P S P+Y+ PS P PPP P + A A G G
Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGP-------FPPSTG 467
Query: 423 AQYAAASPAWA-----AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP 477
AQ A P QQ+ P P P L G GS+
Sbjct: 468 AQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP-LEG-GSSH 525
Query: 478 HSQPQQSSPYPGGSYG-PPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQ 536
H+ P SP G PPGP P P + PP S
Sbjct: 526 HAHPYAMSPSLGSLRPYPPGPAHLP------PPHSQVSYSQAGPNGPPVSSSSNSSSSTS 579
Query: 537 QGQQPYYSQQPQPPHLPPQAQY---------LPSQSQQRYQPQQDMSQEGYGTRSQPPLA 587
QG P P P P A Y S + S GY T S P
Sbjct: 580 QGSYP--CSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPP 637
Query: 588 PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQS 647
P + P GS TGT +G + +
Sbjct: 638 PYGKRAPSPGAYKTATPPGYK--PGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPG 695
Query: 648 PFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMP----PQPPGSQSE 703
P P L S+P P+ G P+ + Q + P P S +P P PP +
Sbjct: 696 PLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVD 755
Query: 704 SSSHPALS 711
SH + S
Sbjct: 756 VPSHASQS 763
Score = 80.9 bits (198), Expect = 1e-14
Identities = 144/602 (23%), Positives = 196/602 (32%), Gaps = 97/602 (16%)
Query: 251 GGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVL 310
GG GG G G GGG + GG G + + G G V
Sbjct: 222 GGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPV- 280
Query: 311 SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSP 370
GG + P ++ A A + GA P L L SP
Sbjct: 281 -----GGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQP-LPGHLPSPHA 334
Query: 371 MMRSYGGSYP-EYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAAS 429
M + GG P P+ P P S P + ++A M Y+++S
Sbjct: 335 MGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAP---------------APPMRFPYSSSS 379
Query: 430 PAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPG 489
+ AAA S + S +P P SQ P P P + + P Q S P
Sbjct: 380 SSSAAASSSSSSSSSSASPFPA---SQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQA 436
Query: 490 -GSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQ 548
S GPP P Y GR +A PP G Q +
Sbjct: 437 VWSQGPPPPPPY-----GR---LLANSNAHPGPFPPSTGAQSTA---------------H 473
Query: 549 PPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLP 608
PP + Q QQ+ Q QQ Q+ + S PP P+ + P ++
Sbjct: 474 PPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMS 533
Query: 609 DLSGSIDDLPTG--------TEATLSSA-------VSASGSTSSQGDQSNPAQSPFSPHA 653
GS+ P G ++ + S A S+S S+SS S P P SP
Sbjct: 534 PSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP-SPSQ 592
Query: 654 SPHLSSIPGGPSPSPVGSPVGSNQSRSGPISP-----ASIPGSQMPPQPPGSQSESSSHP 708
P G P P P PV + + S +S AS P PPG P
Sbjct: 593 GPQ-----GAPYPFP---PVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP 644
Query: 709 ALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGT 768
+ G+ G +P + G SP PG +F+ + +
Sbjct: 645 SPGAYKTATPPGYKPG---SPPSFRTGTPPGYRGTSPPAGPG--------TFKPGSPTVG 693
Query: 769 YGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRM 828
GP + GP G S PP P+A S GP + + Q + P VP R
Sbjct: 694 PGP-LPPAGPSGLPSLPPP----PAAPAS--GPPLSATQIKQEPAEEYETPESPVPPARS 746
Query: 829 PS 830
PS
Sbjct: 747 PS 748
Score = 77.0 bits (188), Expect = 2e-13
Identities = 188/853 (22%), Positives = 276/853 (32%), Gaps = 194/853 (22%)
Query: 841 NMSSMTPSSPGMSQQGGP-----GMGPPMPT-VNRKAQEAAAAVMQAAANSAQSRQGSFP 894
N SM+ S + GP G P V+ + + A + A A+ + S P
Sbjct: 6 NKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTP 65
Query: 895 GMNQSGLMAS-SSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKL 953
+N+ G S S+ N Q P +P+ ++S ++ S
Sbjct: 66 KVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGR-----SLNDDGSSD 120
Query: 954 PLPLKADGKEEGTP--QPESKSKDSYSSQGISQPPT----PGNLPVPSPMSPSSASISSF 1007
P + D + P S DS SS G+SQ P P L PSP P S
Sbjct: 121 PRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDS------ 174
Query: 1008 HGDESDSISSPGWPKTPSSPKSS-----SSTTTGEKITKVYELGNEPERKLWVDRYLTFM 1062
TP P++S S T TG Y EP F
Sbjct: 175 ---------------TPRQPEASFEPHPSVTPTG------YHAPMEPPTSRM------FQ 207
Query: 1063 EERGSP-------------VSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELAT 1109
G+P V S P +G K +GG N K+ T
Sbjct: 208 APPGAPPPHPQLYPGGTGGVLSGPPMGPKGGG------AASSVGG---PNGGKQHPPPTT 258
Query: 1110 NLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPS---PA 1166
++V +S ++ + K + PPP F P L PP P
Sbjct: 259 PISVSSSGASGAPPTKPPTTPVGGGNLP----SAPPPANFP----HVTPNLPPPPALRPL 310
Query: 1167 NSGSLQGP-----------QTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSST 1215
N+ S P +P + G PG K PT A +PH P +
Sbjct: 311 NNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS--LPPASSSAPA 368
Query: 1216 ISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSE 1275
+ P+S S SS +S + ++ + PF + +P
Sbjct: 369 PPMRFPYSSSSSSSAAASSSSSSSSS------------------SASPFPASQALPSYPH 410
Query: 1276 PFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPS 1335
F + S+ Y Q + + G PYG R +PG PPS
Sbjct: 411 SFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYG-----RLLANSNAHPGPFPPS 465
Query: 1336 GQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSG 1395
G Q +P + H H+ Q QQQ+ Q+ G+ SG
Sbjct: 466 T-----GAQSTAHPPVSTHHHH-----------HQQQQQQQQQQQQQQQQQQQHHGN-SG 508
Query: 1396 PDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPY 1455
P P G +P+P ++G H P S S G + +P
Sbjct: 509 P---PPPGAFPHP-----LEGGSSHHAH---------PYAMSPSLGSLRPYPPGPAHLPP 551
Query: 1456 PYQ----NRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPY------- 1504
P+ ++ GP GP P N + +H S PS Q PY
Sbjct: 552 PHSQVSYSQAGPNGP---PVSSSSNSSSSTSQGSYPCSHPS--PSQGPQGAPYPFPPVPT 606
Query: 1505 -MSSSASMQPI-----TRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLP 1558
+SSA++ + + P +PP P + RAPSP +++ + P P
Sbjct: 607 VTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFR 666
Query: 1559 SMKMQKVMPTVPT---------SQVTGPPPQPP--PIRREITFPPGSVEASQPVLK--QR 1605
+ T P S GP P PP P PP + AS P L Q
Sbjct: 667 TGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQI 726
Query: 1606 RKITSKDIVTPEA 1618
++ +++ TPE+
Sbjct: 727 KQEPAEEYETPES 739
Score = 62.4 bits (150), Expect = 5e-09
Identities = 73/279 (26%), Positives = 92/279 (32%), Gaps = 67/279 (24%)
Query: 13 TVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQ 72
+ G A P HHHHH QQQQQQQQQQQQQQQQQ
Sbjct: 465 STGAQSTAHPPVSTHHHHHQ-----------------------QQQQQQQQQQQQQQQQQ 501
Query: 73 QHPISNNNSLGGA------GGGAPQPGPDMEQPQHGGAKDSAAG-------------GQA 113
QH ++ GA GG + P P G + G QA
Sbjct: 502 QHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQA 561
Query: 114 DPPGPPLLSKPGDEDDA---------PPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGG 164
P GPP+ S P P G Y P + + T ++
Sbjct: 562 GPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTV---- 617
Query: 165 GPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDP 224
A V Y +A+P P G+ P SPG + G+P S
Sbjct: 618 -IATVASSPAGYKTASPPGPPPYGKRAP---------SPGAYKTATPPGYKPGSPPSF-- 665
Query: 225 LQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSG 263
+ GY + PG +PG+ G G G SG
Sbjct: 666 RTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG 704
Score = 52.0 bits (123), Expect = 7e-06
Identities = 160/727 (22%), Positives = 241/727 (33%), Gaps = 152/727 (20%)
Query: 635 TSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMP 694
+ S+ +++N +P + +P SPS + S G + + G P I
Sbjct: 77 SESESEETN------APKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRS 130
Query: 695 PQP----PGS-QSESSSHPALSQSPMPQERGFMAGT--QRNPQMAQYGPQQTGPSMSPHP 747
P PGS +++S S LSQ P R + +PQ P+Q S PHP
Sbjct: 131 TSPSIYSPGSVENDSDSSSGLSQGPA---RPYHPPPLFPPSPQPPDSTPRQPEASFEPHP 187
Query: 748 SPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISA 807
S G + + +S +M Q P P Y G SGP G
Sbjct: 188 SV---TPTGYHAPMEPPTS-----RMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGP---- 235
Query: 808 NNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTV 867
G G + G P+ G Q+ P + ++ SS G S G P PP V
Sbjct: 236 ----KGGGAASSVGG------PNGGKQHPP---PTTPISVSSSGAS--GAPPTKPPTTPV 280
Query: 868 NRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYS 927
+ P + P N + PP +
Sbjct: 281 G----------------------------------GGNLPSAPPPANFPHVTPNLPPPPA 306
Query: 928 MAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPT 987
+ P + N+SA+ GL PG LP P A G+ G P + + + S PP
Sbjct: 307 LRP-LNNASASPPGLGAQPLPGH--LPSP-HAMGQGMGGLPPGPEKGPTLAPSPHSLPPA 362
Query: 988 PGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSSPKSSSSTTTGEKITKVYELGN 1047
+ P P P S+S SS S S SS SS+S + Y
Sbjct: 363 SSSAPAPPMRFPYSSSSSSSAAASSSS----------SSSSSSASPFPASQALPSYPHSF 412
Query: 1048 EPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWREL 1107
P L V + P ++ + G P + G N N
Sbjct: 413 PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPY----------GRLLANSNAHPGPF 462
Query: 1108 ATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPAN 1167
+ G S+A + + + + + ++ ++ + G++ P P P
Sbjct: 463 PP--STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLE 520
Query: 1168 SGSLQGPQTPQSTGSNSMAEVPGDLK--PPTPA--STPHGQMTPMQGGRSSTISVHDPFS 1223
GS +M+ G L+ PP PA PH Q++ Q G + P S
Sbjct: 521 GGS------SHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNG-----PPVS 569
Query: 1224 DVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQM 1283
S+SS S T Y S P P++ P G P P +T
Sbjct: 570 SSSNSS-----SSTSQGSYP--CSHP--------SPSQGPQGA--PYPFPPVPTVTTSSA 612
Query: 1284 PNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGP-PSGQPPYGG 1342
S++ SP+G Y + PYG++ P G + PP G
Sbjct: 613 TLSTVIATVASSPAG--------------YKTASPPGPPPYGKRAPSPGAYKTATPP--G 656
Query: 1343 HQPGLYP 1349
++PG P
Sbjct: 657 YKPGSPP 663
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 105 bits (261), Expect = 6e-22
Identities = 268/1105 (24%), Positives = 344/1105 (31%), Gaps = 217/1105 (19%)
Query: 63 QQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS 122
Q+ Q Q QQ I+ G G +PGP + P GAK + G P GP +
Sbjct: 524 QEAQAQAILQQARIALRGPPGPMGLTG-RPGP-VGGPGSSGAKGES--GDPGPQGPRGVQ 579
Query: 123 KPGDEDDAPPKMGEPA--GGRYEHPGLGALGT-----------------QQPPVAVPGGG 163
P P K G P GGR GA G ++ P PG
Sbjct: 580 GPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP 639
Query: 164 GGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMD 223
G E P GP G GP G +PG M G G+M
Sbjct: 640 GDDGMRGEDGEIGPRGLPGEAGPRGLLGP----RGTPGAPGQPGMAGVDGPP-GPKGNMG 694
Query: 224 PLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGG--GGGGGSGGGGGGGGAGAGGAGAGAV 281
P G P Q N PG G G G G G G G G AG GA
Sbjct: 695 P--QGEPGPPGQQGN-------PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD---- 741
Query: 282 AAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGP----GGGGAASLSKAAA 337
G G G G S G L P QG GP G G L +
Sbjct: 742 -----------GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKG 790
Query: 338 GSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQS 397
GF F G + G + Q+ G PE A P P
Sbjct: 791 EKGEDGFPGFKG-DMGLKGDRGEVGQI--------GPRGEDGPEGPKGRAGPTGDPGPSG 841
Query: 398 QAAAAGAAA-------GGQQAAAGM-------GLGKDMGAQYAAASPAWAAAQQRSHPAM 443
QA G G+Q G G + GA+ A P + + P
Sbjct: 842 QAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG 901
Query: 444 SPGTPGPT-----MGRSQGS-PMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGP 497
S G GPT G S G P P + PQ PQ +PG GPPGP
Sbjct: 902 SRGARGPTGKPGPKGTSGGDGPPGPPGERGPQ----------GPQGPVGFPGPK-GPPGP 950
Query: 498 -----------QRYPIGIQGRT----PGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPY 542
QR G QG+T PG + G Q P + P G++G
Sbjct: 951 PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGP-IGERG------------ 997
Query: 543 YSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDL------ 596
P PP PP Q LP + + + D +G + P G P L
Sbjct: 998 ---HPGPPG-PPGEQGLPGAAGKE-GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA 1052
Query: 597 -NLIQQERPSSLPDLSGSIDDLPTGTEAT---LSSAVSASGSTSSQGDQSNPAQS-PFSP 651
L E P P GS + + A L G G++ P + P P
Sbjct: 1053 PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1112
Query: 652 HASPHLSSIPGGPSPS-PVGSPVGSNQSRSGPISPASIPGSQM------PPQPPGSQSES 704
+ G P P+ P GSP G I GS+ PP PPG Q
Sbjct: 1113 AGRDGVQGPVGLPGPAGPAGSP--GEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPV 1170
Query: 705 SSHPALSQS---PMPQERGFMAGTQRNPQMAQYGPQQTGP-SMSPHPSPGGQM--HAGIS 758
+ P ++ P P+ + M G Q+ + A+ P GP + P P G+ + +
Sbjct: 1171 GA-PGIAGGDGEPGPRGQQGMFG-QKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVG 1228
Query: 759 SFQQSNSSGTYGPQ--MSQYGPQGNYSRPPAYSGVPSASYSG----PGPG--MGISANNQ 810
G GPQ GPQG + GV G PGP G+
Sbjct: 1229 PMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKG 1288
Query: 811 MHGQ-GPSQPCGAV--PLGRMPSA--GMQNRP----FPGNMSSMTPSSPGMSQQGGPG-- 859
G+ G + P GA P + P G + P FPG+ P PG + Q G G
Sbjct: 1289 ERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP--PGEPGPAGQDGVGGD 1346
Query: 860 ------------------MGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGL 901
GPP P R AA A + A+ G+ ++G
Sbjct: 1347 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1406
Query: 902 MASSSPYSQP-------------MNNSSSLMNTQAPPYSMAPAMVNSSAASVGL-ADMMS 947
+ P +P PP M P + G +
Sbjct: 1407 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGH 1466
Query: 948 PGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPT-----PGNLPVPSPMSPSSA 1002
PG L P G++ P ++ G P PG +P P P
Sbjct: 1467 PGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1526
Query: 1003 SISSFHGDESDSISSPGWPKTPSSP 1027
S+ + PG P +P P
Sbjct: 1527 KGSTGPAGQKGDSGLPGPPGSPGPP 1551
Score = 88.2 bits (217), Expect = 8e-17
Identities = 205/839 (24%), Positives = 260/839 (30%), Gaps = 163/839 (19%)
Query: 67 QQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGD 126
+ ++ + P S N G G A + HG A G+ G P + +PG
Sbjct: 397 EYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHG------AYGEKGQKGEPAVVEPGM 450
Query: 127 EDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPG--GGGGPAAVPEFNNYYGSAAPAS- 183
+ PP PA G PGL Q P PG G GP P G P
Sbjct: 451 LVEGPPGPAGPA-GIMGPPGL------QGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGT 503
Query: 184 --------GGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNS 235
GG G + GP Q++ ++ A A G PG M
Sbjct: 504 MLMLPFRYGGDGSK-GPTI---SAQEAQAQAILQQARIALRGPPGPMGLT---------- 549
Query: 236 QCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGG 295
RPG GG G G G SG G G G G A GG
Sbjct: 550 --------GRPGP-VGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 600
Query: 296 GGGGYGGSSA--GY-GVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQ 352
G G G+ G+ G+ P +G GP G G G
Sbjct: 601 GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGE-----IGPRG 655
Query: 353 HPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAA 412
P A P LL P P P QP A G
Sbjct: 656 LPGEAGP--RGLL------------------GPRGTPGAPGQP------GMAGVDGPPGP 689
Query: 413 AGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYG 472
G +MG Q P Q P PG GP G P + +P L G
Sbjct: 690 KG-----NMGPQ---GEPGPPGQQGNPGPQGLPGPQGPI-----GPPGEKGPQGKPGLAG 736
Query: 473 M--GSNPHSQP-QQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQ 529
+ P P ++ G+ GPPGPQ PIG G A + + G+
Sbjct: 737 LPGADGPPGHPGKEGQSGEKGALGPPGPQG-PIGYPGPRGVKGADGVRGLKGSKGEKGED 795
Query: 530 GVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPG 589
G G+ +G + + + P+ + P + R P D G PG
Sbjct: 796 GFPGF--KGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 853
Query: 590 KPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPA---- 645
P + P G P G+ A+G ++G P
Sbjct: 854 LPGY--------------PGRQG-----PKGSTG-FPGFPGANGEKGARGVAGKPGPRGQ 893
Query: 646 QSPFSPHASPHLSSIPGGPSP-------SPVGSPVGSNQSRSGPISPASIPGSQMPPQPP 698
+ P P S G P P P G P + GP P PG + PP PP
Sbjct: 894 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPP--GERGPQGPQGPVGFPGPKGPPGPP 951
Query: 699 GSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQ----QTGP-SMSPHPSPGGQM 753
G HP E GF T GPQ +TGP HP P G
Sbjct: 952 GKDG-LPGHPG-----QRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 1005
Query: 754 -HAGI-SSFQQSNSSGTYGPQ--MSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANN 809
G+ + + + G GPQ + GP G P G+P A PG+
Sbjct: 1006 GEQGLPGAAGKEGAKGDPGPQGISGKDGPAG-LRGFPGERGLPGAQ---GAPGL------ 1055
Query: 810 QMHGQGPSQPCGAV-PLGRMPSAGMQNR-PFPGNMSSMTPSSPGMSQQGGPG-MGPPMP 865
G+GP P G V G SAG PG P P ++G PG GP P
Sbjct: 1056 -KGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPA-GEKGAPGEKGPQGP 1112
Score = 86.7 bits (213), Expect = 2e-16
Identities = 172/686 (25%), Positives = 205/686 (29%), Gaps = 114/686 (16%)
Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPP----LLSKPGDEDDA-------PP 132
G GG PGP E+ G G PPGPP L PG + PP
Sbjct: 916 GTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP 975
Query: 133 KMGE---PAGGRYEHPGLGALGTQQPP-----VAVPGGGG--GPAAVPEFNNYYGSAAPA 182
G P G E +G G PP +PG G G P G PA
Sbjct: 976 GPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA 1035
Query: 183 S--GGPGGRAGPCFDQHGGQQSPGM--GMMHSASAAAAGAPGSMDPLQNSHE-GYPNSQC 237
G PG R P G Q +PG+ G G+PG + G P
Sbjct: 1036 GLRGFPGERGLP-----GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR-- 1088
Query: 238 NHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGG 297
PG P G G G G G G G G G A A + G G
Sbjct: 1089 ---PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1145
Query: 298 GGYGGSSAGYGVLSSPRQQG-GGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSG 356
G GS G P G G + PG G G + G P
Sbjct: 1146 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP 1205
Query: 357 ATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQ-------PQSQAAAAGAAAG-- 407
P Q L P P + G P P P Q PQ + G+ G
Sbjct: 1206 PGPIGLQGLPGP-PGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1264
Query: 408 -----------GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSP----GTPGPT- 451
G AG+G K + A P AA + G PGP
Sbjct: 1265 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVG 1324
Query: 452 MGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGP--QRYPIGIQGRT- 508
G P +P + + G Q P P G GPPGP +R P G G
Sbjct: 1325 FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG 1384
Query: 509 ----PGAM--AGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHL-----PPQAQ 557
GA AG + P + P G QG +G +P P L P Q
Sbjct: 1385 RQGEKGAKGEAGAEGPPGKTGP-VGPQGPAG------------KPGPEGLRGIPGPVGEQ 1431
Query: 558 YLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDL 617
LP + Q P M G P + G+ H P L G I
Sbjct: 1432 GLPGAAGQD-GPPGPMGPPGLPGLKGDPGSKGEKGH--------------PGLIGLIGPP 1476
Query: 618 PTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQ 677
E GS ++GD P P P P +PG P N+
Sbjct: 1477 GEQGEKGDRGLPGTQGSPGAKGDGGIPG--PAGPLGPPGPPGLPGPQGPK-------GNK 1527
Query: 678 SRSGPISPASIPGSQMPPQPPGSQSE 703
+GP G PP PG E
Sbjct: 1528 GSTGPAGQKGDSGLPGPPGSPGPPGE 1553
Score = 78.6 bits (192), Expect = 7e-14
Identities = 152/620 (24%), Positives = 191/620 (30%), Gaps = 110/620 (17%)
Query: 82 LGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGR 141
L G G PGP + G A + G PGP P E AP + G P G
Sbjct: 1055 LKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG-PQGPA 1113
Query: 142 YEHPGLGALGTQQP--PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAG-----PCF 194
G +G P P PG G + E GP G G
Sbjct: 1114 GRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAP 1173
Query: 195 DQHGGQQSPG----MGMM-HSASAAAAGAPGSMDPL-QNSHEGYPNSQCNH-------YP 241
GG PG GM A G PG P+ G P + + P
Sbjct: 1174 GIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1233
Query: 242 GYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYG 301
G P G G G G G G GG G G A A G G G
Sbjct: 1234 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1293
Query: 302 GSSAGYGVLSSPRQQG----------GGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQN 351
G + G P +G G + PG G A GG + G++
Sbjct: 1294 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDK---GED 1350
Query: 352 QHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQA 411
P P P P S + PP PP + AA G++
Sbjct: 1351 GDPG-----------QPGP---------PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKG 1390
Query: 412 AAG-------MGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMV 464
A G G +G Q A P + P G PG PM P
Sbjct: 1391 AKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP-- 1448
Query: 465 MKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQ-----RYPIGIQGRTPGAMAGMQYPQ 519
P L G+ +P S+ ++ P G GPPG Q R G QG +PGA P
Sbjct: 1449 ---PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQG-SPGAKGDGGIP- 1503
Query: 520 QQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP-PQAQYLPSQSQQRYQPQQDMSQEGY 578
G G G P PP LP PQ P ++ P Q+G
Sbjct: 1504 -------GPAGPLG------------PPGPPGLPGPQG---PKGNKGSTGP---AGQKGD 1538
Query: 579 GTRSQPPLAPGKPNH--EDLNLIQQER-----PSSLPDLSGSIDDLPTGTEATLSSAVSA 631
PP +PG P + L ++ ++ D +I D G E S S
Sbjct: 1539 SGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSL 1598
Query: 632 SGSTS----SQGDQSNPAQS 647
G Q+NPA++
Sbjct: 1599 KQDIEHMKFPMGTQTNPART 1618
Score = 40.4 bits (93), Expect = 0.020
Identities = 101/427 (23%), Positives = 139/427 (32%), Gaps = 74/427 (17%)
Query: 601 QERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSI 660
+++P+S P+ +P T+ T +S ++ G+ +G + PA +
Sbjct: 402 EDKPTSPPNEEFG-PGVPAETDITETS-INGHGAYGEKGQKGEPAVV----EPGMLVEGP 455
Query: 661 PGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMP------------PQPPGSQ------- 701
PG P+ + P G GP P PG + P P PPG+
Sbjct: 456 PGPAGPAGIMGPPGLQ----GPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRY 511
Query: 702 -SESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGP-SMSPHPSPGGQMHAGISS 759
+ S P +S QE A Q+ ++A GP GP ++ P P G G S
Sbjct: 512 GGDGSKGPTIS----AQEAQAQAILQQ-ARIALRGP--PGPMGLTGRPGPVG----GPGS 560
Query: 760 FQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVP-SASYSGPGPGMGISANNQMHGQGPSQ 818
SG GPQ GP+G PP +G P G G G+ G
Sbjct: 561 SGAKGESGDPGPQ----GPRG-VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD 615
Query: 819 PCGAVP--LGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAA 876
+P G G Q P P M + +G PG P + + A
Sbjct: 616 GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAP 675
Query: 877 AVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSS 936
Q G M G P Q L Q P + P
Sbjct: 676 G--QPGMAGVDGPPGPKGNMGPQG--EPGPPGQQGNPGPQGLPGPQGP---IGPPGEKGP 728
Query: 937 AASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTP-GNLPVPS 995
GLA + PG ADG G P E +S +G PP P G + P
Sbjct: 729 QGKPGLAGL--PG---------ADG-PPGHPGKEGQS----GEKGALGPPGPQGPIGYPG 772
Query: 996 PMSPSSA 1002
P A
Sbjct: 773 PRGVKGA 779
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 105 bits (261), Expect = 6e-22
Identities = 268/1105 (24%), Positives = 344/1105 (31%), Gaps = 217/1105 (19%)
Query: 63 QQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS 122
Q+ Q Q QQ I+ G G +PGP + P GAK + G P GP +
Sbjct: 473 QEAQAQAILQQARIALRGPPGPMGLTG-RPGP-VGGPGSSGAKGES--GDPGPQGPRGVQ 528
Query: 123 KPGDEDDAPPKMGEPA--GGRYEHPGLGALGT-----------------QQPPVAVPGGG 163
P P K G P GGR GA G ++ P PG
Sbjct: 529 GPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP 588
Query: 164 GGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMD 223
G E P GP G GP G +PG M G G+M
Sbjct: 589 GDDGMRGEDGEIGPRGLPGEAGPRGLLGP----RGTPGAPGQPGMAGVDGPP-GPKGNMG 643
Query: 224 PLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGG--GGGGGSGGGGGGGGAGAGGAGAGAV 281
P G P Q N PG G G G G G G G G AG GA
Sbjct: 644 P--QGEPGPPGQQGN-------PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD---- 690
Query: 282 AAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGP----GGGGAASLSKAAA 337
G G G G S G L P QG GP G G L +
Sbjct: 691 -----------GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKG 739
Query: 338 GSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQS 397
GF F G + G + Q+ G PE A P P
Sbjct: 740 EKGEDGFPGFKG-DMGLKGDRGEVGQI--------GPRGEDGPEGPKGRAGPTGDPGPSG 790
Query: 398 QAAAAGAAA-------GGQQAAAGM-------GLGKDMGAQYAAASPAWAAAQQRSHPAM 443
QA G G+Q G G + GA+ A P + + P
Sbjct: 791 QAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG 850
Query: 444 SPGTPGPT-----MGRSQGS-PMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGP 497
S G GPT G S G P P + PQ PQ +PG GPPGP
Sbjct: 851 SRGARGPTGKPGPKGTSGGDGPPGPPGERGPQ----------GPQGPVGFPGPK-GPPGP 899
Query: 498 -----------QRYPIGIQGRT----PGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPY 542
QR G QG+T PG + G Q P + P G++G
Sbjct: 900 PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGP-IGERG------------ 946
Query: 543 YSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDL------ 596
P PP PP Q LP + + + D +G + P G P L
Sbjct: 947 ---HPGPPG-PPGEQGLPGAAGKE-GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA 1001
Query: 597 -NLIQQERPSSLPDLSGSIDDLPTGTEAT---LSSAVSASGSTSSQGDQSNPAQS-PFSP 651
L E P P GS + + A L G G++ P + P P
Sbjct: 1002 PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1061
Query: 652 HASPHLSSIPGGPSPS-PVGSPVGSNQSRSGPISPASIPGSQM------PPQPPGSQSES 704
+ G P P+ P GSP G I GS+ PP PPG Q
Sbjct: 1062 AGRDGVQGPVGLPGPAGPAGSP--GEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPV 1119
Query: 705 SSHPALSQS---PMPQERGFMAGTQRNPQMAQYGPQQTGP-SMSPHPSPGGQM--HAGIS 758
+ P ++ P P+ + M G Q+ + A+ P GP + P P G+ + +
Sbjct: 1120 GA-PGIAGGDGEPGPRGQQGMFG-QKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVG 1177
Query: 759 SFQQSNSSGTYGPQ--MSQYGPQGNYSRPPAYSGVPSASYSG----PGPG--MGISANNQ 810
G GPQ GPQG + GV G PGP G+
Sbjct: 1178 PMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKG 1237
Query: 811 MHGQ-GPSQPCGAV--PLGRMPSA--GMQNRP----FPGNMSSMTPSSPGMSQQGGPG-- 859
G+ G + P GA P + P G + P FPG+ P PG + Q G G
Sbjct: 1238 ERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP--PGEPGPAGQDGVGGD 1295
Query: 860 ------------------MGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGL 901
GPP P R AA A + A+ G+ ++G
Sbjct: 1296 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1355
Query: 902 MASSSPYSQP-------------MNNSSSLMNTQAPPYSMAPAMVNSSAASVGL-ADMMS 947
+ P +P PP M P + G +
Sbjct: 1356 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGH 1415
Query: 948 PGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPT-----PGNLPVPSPMSPSSA 1002
PG L P G++ P ++ G P PG +P P P
Sbjct: 1416 PGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1475
Query: 1003 SISSFHGDESDSISSPGWPKTPSSP 1027
S+ + PG P +P P
Sbjct: 1476 KGSTGPAGQKGDSGLPGPPGSPGPP 1500
Score = 88.2 bits (217), Expect = 8e-17
Identities = 205/839 (24%), Positives = 260/839 (30%), Gaps = 163/839 (19%)
Query: 67 QQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGD 126
+ ++ + P S N G G A + HG A G+ G P + +PG
Sbjct: 346 EYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHG------AYGEKGQKGEPAVVEPGM 399
Query: 127 EDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPG--GGGGPAAVPEFNNYYGSAAPAS- 183
+ PP PA G PGL Q P PG G GP P G P
Sbjct: 400 LVEGPPGPAGPA-GIMGPPGL------QGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGT 452
Query: 184 --------GGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNS 235
GG G + GP Q++ ++ A A G PG M
Sbjct: 453 MLMLPFRYGGDGSK-GPTI---SAQEAQAQAILQQARIALRGPPGPMGLT---------- 498
Query: 236 QCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGG 295
RPG GG G G G SG G G G G A GG
Sbjct: 499 --------GRPGP-VGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 549
Query: 296 GGGGYGGSSA--GY-GVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQ 352
G G G+ G+ G+ P +G GP G G G
Sbjct: 550 GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGE-----IGPRG 604
Query: 353 HPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAA 412
P A P LL P P P QP A G
Sbjct: 605 LPGEAGP--RGLL------------------GPRGTPGAPGQP------GMAGVDGPPGP 638
Query: 413 AGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYG 472
G +MG Q P Q P PG GP G P + +P L G
Sbjct: 639 KG-----NMGPQ---GEPGPPGQQGNPGPQGLPGPQGPI-----GPPGEKGPQGKPGLAG 685
Query: 473 M--GSNPHSQP-QQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQ 529
+ P P ++ G+ GPPGPQ PIG G A + + G+
Sbjct: 686 LPGADGPPGHPGKEGQSGEKGALGPPGPQG-PIGYPGPRGVKGADGVRGLKGSKGEKGED 744
Query: 530 GVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPG 589
G G+ +G + + + P+ + P + R P D G PG
Sbjct: 745 GFPGF--KGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 802
Query: 590 KPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPA---- 645
P + P G P G+ A+G ++G P
Sbjct: 803 LPGY--------------PGRQG-----PKGSTG-FPGFPGANGEKGARGVAGKPGPRGQ 842
Query: 646 QSPFSPHASPHLSSIPGGPSP-------SPVGSPVGSNQSRSGPISPASIPGSQMPPQPP 698
+ P P S G P P P G P + GP P PG + PP PP
Sbjct: 843 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPP--GERGPQGPQGPVGFPGPKGPPGPP 900
Query: 699 GSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQ----QTGP-SMSPHPSPGGQM 753
G HP E GF T GPQ +TGP HP P G
Sbjct: 901 GKDG-LPGHPG-----QRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 954
Query: 754 -HAGI-SSFQQSNSSGTYGPQ--MSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANN 809
G+ + + + G GPQ + GP G P G+P A PG+
Sbjct: 955 GEQGLPGAAGKEGAKGDPGPQGISGKDGPAG-LRGFPGERGLPGAQ---GAPGL------ 1004
Query: 810 QMHGQGPSQPCGAV-PLGRMPSAGMQNR-PFPGNMSSMTPSSPGMSQQGGPG-MGPPMP 865
G+GP P G V G SAG PG P P ++G PG GP P
Sbjct: 1005 -KGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPA-GEKGAPGEKGPQGP 1061
Score = 86.7 bits (213), Expect = 2e-16
Identities = 172/686 (25%), Positives = 205/686 (29%), Gaps = 114/686 (16%)
Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPP----LLSKPGDEDDA-------PP 132
G GG PGP E+ G G PPGPP L PG + PP
Sbjct: 865 GTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP 924
Query: 133 KMGE---PAGGRYEHPGLGALGTQQPP-----VAVPGGGG--GPAAVPEFNNYYGSAAPA 182
G P G E +G G PP +PG G G P G PA
Sbjct: 925 GPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA 984
Query: 183 S--GGPGGRAGPCFDQHGGQQSPGM--GMMHSASAAAAGAPGSMDPLQNSHE-GYPNSQC 237
G PG R P G Q +PG+ G G+PG + G P
Sbjct: 985 GLRGFPGERGLP-----GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR-- 1037
Query: 238 NHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGG 297
PG P G G G G G G G G G A A + G G
Sbjct: 1038 ---PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1094
Query: 298 GGYGGSSAGYGVLSSPRQQG-GGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSG 356
G GS G P G G + PG G G + G P
Sbjct: 1095 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP 1154
Query: 357 ATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQ-------PQSQAAAAGAAAG-- 407
P Q L P P + G P P P Q PQ + G+ G
Sbjct: 1155 PGPIGLQGLPGP-PGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1213
Query: 408 -----------GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSP----GTPGPT- 451
G AG+G K + A P AA + G PGP
Sbjct: 1214 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVG 1273
Query: 452 MGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGP--QRYPIGIQGRT- 508
G P +P + + G Q P P G GPPGP +R P G G
Sbjct: 1274 FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG 1333
Query: 509 ----PGAM--AGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHL-----PPQAQ 557
GA AG + P + P G QG +G +P P L P Q
Sbjct: 1334 RQGEKGAKGEAGAEGPPGKTGP-VGPQGPAG------------KPGPEGLRGIPGPVGEQ 1380
Query: 558 YLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDL 617
LP + Q P M G P + G+ H P L G I
Sbjct: 1381 GLPGAAGQD-GPPGPMGPPGLPGLKGDPGSKGEKGH--------------PGLIGLIGPP 1425
Query: 618 PTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQ 677
E GS ++GD P P P P +PG P N+
Sbjct: 1426 GEQGEKGDRGLPGTQGSPGAKGDGGIPG--PAGPLGPPGPPGLPGPQGPK-------GNK 1476
Query: 678 SRSGPISPASIPGSQMPPQPPGSQSE 703
+GP G PP PG E
Sbjct: 1477 GSTGPAGQKGDSGLPGPPGSPGPPGE 1502
Score = 78.6 bits (192), Expect = 7e-14
Identities = 152/620 (24%), Positives = 191/620 (30%), Gaps = 110/620 (17%)
Query: 82 LGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGR 141
L G G PGP + G A + G PGP P E AP + G P G
Sbjct: 1004 LKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG-PQGPA 1062
Query: 142 YEHPGLGALGTQQP--PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAG-----PCF 194
G +G P P PG G + E GP G G
Sbjct: 1063 GRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAP 1122
Query: 195 DQHGGQQSPG----MGMM-HSASAAAAGAPGSMDPL-QNSHEGYPNSQCNH-------YP 241
GG PG GM A G PG P+ G P + + P
Sbjct: 1123 GIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1182
Query: 242 GYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYG 301
G P G G G G G G GG G G A A G G G
Sbjct: 1183 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1242
Query: 302 GSSAGYGVLSSPRQQG----------GGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQN 351
G + G P +G G + PG G A GG + G++
Sbjct: 1243 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDK---GED 1299
Query: 352 QHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQA 411
P P P P S + PP PP + AA G++
Sbjct: 1300 GDPG-----------QPGP---------PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKG 1339
Query: 412 AAG-------MGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMV 464
A G G +G Q A P + P G PG PM P
Sbjct: 1340 AKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP-- 1397
Query: 465 MKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQ-----RYPIGIQGRTPGAMAGMQYPQ 519
P L G+ +P S+ ++ P G GPPG Q R G QG +PGA P
Sbjct: 1398 ---PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQG-SPGAKGDGGIP- 1452
Query: 520 QQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP-PQAQYLPSQSQQRYQPQQDMSQEGY 578
G G G P PP LP PQ P ++ P Q+G
Sbjct: 1453 -------GPAGPLG------------PPGPPGLPGPQG---PKGNKGSTGP---AGQKGD 1487
Query: 579 GTRSQPPLAPGKPNH--EDLNLIQQER-----PSSLPDLSGSIDDLPTGTEATLSSAVSA 631
PP +PG P + L ++ ++ D +I D G E S S
Sbjct: 1488 SGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSL 1547
Query: 632 SGSTS----SQGDQSNPAQS 647
G Q+NPA++
Sbjct: 1548 KQDIEHMKFPMGTQTNPART 1567
Score = 40.4 bits (93), Expect = 0.020
Identities = 101/427 (23%), Positives = 139/427 (32%), Gaps = 74/427 (17%)
Query: 601 QERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSI 660
+++P+S P+ +P T+ T +S ++ G+ +G + PA +
Sbjct: 351 EDKPTSPPNEEFG-PGVPAETDITETS-INGHGAYGEKGQKGEPAVV----EPGMLVEGP 404
Query: 661 PGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMP------------PQPPGSQ------- 701
PG P+ + P G GP P PG + P P PPG+
Sbjct: 405 PGPAGPAGIMGPPGLQ----GPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRY 460
Query: 702 -SESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGP-SMSPHPSPGGQMHAGISS 759
+ S P +S QE A Q+ ++A GP GP ++ P P G G S
Sbjct: 461 GGDGSKGPTIS----AQEAQAQAILQQ-ARIALRGP--PGPMGLTGRPGPVG----GPGS 509
Query: 760 FQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVP-SASYSGPGPGMGISANNQMHGQGPSQ 818
SG GPQ GP+G PP +G P G G G+ G
Sbjct: 510 SGAKGESGDPGPQ----GPRG-VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD 564
Query: 819 PCGAVP--LGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAA 876
+P G G Q P P M + +G PG P + + A
Sbjct: 565 GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAP 624
Query: 877 AVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSS 936
Q G M G P Q L Q P + P
Sbjct: 625 G--QPGMAGVDGPPGPKGNMGPQG--EPGPPGQQGNPGPQGLPGPQGP---IGPPGEKGP 677
Query: 937 AASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTP-GNLPVPS 995
GLA + PG ADG G P E +S +G PP P G + P
Sbjct: 678 QGKPGLAGL--PG---------ADG-PPGHPGKEGQS----GEKGALGPPGPQGPIGYPG 721
Query: 996 PMSPSSA 1002
P A
Sbjct: 722 PRGVKGA 728
>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
sapiens]
Length = 1806
Score = 105 bits (261), Expect = 6e-22
Identities = 268/1105 (24%), Positives = 344/1105 (31%), Gaps = 217/1105 (19%)
Query: 63 QQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS 122
Q+ Q Q QQ I+ G G +PGP + P GAK + G P GP +
Sbjct: 512 QEAQAQAILQQARIALRGPPGPMGLTG-RPGP-VGGPGSSGAKGES--GDPGPQGPRGVQ 567
Query: 123 KPGDEDDAPPKMGEPA--GGRYEHPGLGALGT-----------------QQPPVAVPGGG 163
P P K G P GGR GA G ++ P PG
Sbjct: 568 GPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP 627
Query: 164 GGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMD 223
G E P GP G GP G +PG M G G+M
Sbjct: 628 GDDGMRGEDGEIGPRGLPGEAGPRGLLGP----RGTPGAPGQPGMAGVDGPP-GPKGNMG 682
Query: 224 PLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGG--GGGGGSGGGGGGGGAGAGGAGAGAV 281
P G P Q N PG G G G G G G G G AG GA
Sbjct: 683 P--QGEPGPPGQQGN-------PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD---- 729
Query: 282 AAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGP----GGGGAASLSKAAA 337
G G G G S G L P QG GP G G L +
Sbjct: 730 -----------GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKG 778
Query: 338 GSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQS 397
GF F G + G + Q+ G PE A P P
Sbjct: 779 EKGEDGFPGFKG-DMGLKGDRGEVGQI--------GPRGEDGPEGPKGRAGPTGDPGPSG 829
Query: 398 QAAAAGAAA-------GGQQAAAGM-------GLGKDMGAQYAAASPAWAAAQQRSHPAM 443
QA G G+Q G G + GA+ A P + + P
Sbjct: 830 QAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG 889
Query: 444 SPGTPGPT-----MGRSQGS-PMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGP 497
S G GPT G S G P P + PQ PQ +PG GPPGP
Sbjct: 890 SRGARGPTGKPGPKGTSGGDGPPGPPGERGPQ----------GPQGPVGFPGPK-GPPGP 938
Query: 498 -----------QRYPIGIQGRT----PGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPY 542
QR G QG+T PG + G Q P + P G++G
Sbjct: 939 PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGP-IGERG------------ 985
Query: 543 YSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDL------ 596
P PP PP Q LP + + + D +G + P G P L
Sbjct: 986 ---HPGPPG-PPGEQGLPGAAGKE-GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA 1040
Query: 597 -NLIQQERPSSLPDLSGSIDDLPTGTEAT---LSSAVSASGSTSSQGDQSNPAQS-PFSP 651
L E P P GS + + A L G G++ P + P P
Sbjct: 1041 PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1100
Query: 652 HASPHLSSIPGGPSPS-PVGSPVGSNQSRSGPISPASIPGSQM------PPQPPGSQSES 704
+ G P P+ P GSP G I GS+ PP PPG Q
Sbjct: 1101 AGRDGVQGPVGLPGPAGPAGSP--GEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPV 1158
Query: 705 SSHPALSQS---PMPQERGFMAGTQRNPQMAQYGPQQTGP-SMSPHPSPGGQM--HAGIS 758
+ P ++ P P+ + M G Q+ + A+ P GP + P P G+ + +
Sbjct: 1159 GA-PGIAGGDGEPGPRGQQGMFG-QKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVG 1216
Query: 759 SFQQSNSSGTYGPQ--MSQYGPQGNYSRPPAYSGVPSASYSG----PGPG--MGISANNQ 810
G GPQ GPQG + GV G PGP G+
Sbjct: 1217 PMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKG 1276
Query: 811 MHGQ-GPSQPCGAV--PLGRMPSA--GMQNRP----FPGNMSSMTPSSPGMSQQGGPG-- 859
G+ G + P GA P + P G + P FPG+ P PG + Q G G
Sbjct: 1277 ERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP--PGEPGPAGQDGVGGD 1334
Query: 860 ------------------MGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGL 901
GPP P R AA A + A+ G+ ++G
Sbjct: 1335 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1394
Query: 902 MASSSPYSQP-------------MNNSSSLMNTQAPPYSMAPAMVNSSAASVGL-ADMMS 947
+ P +P PP M P + G +
Sbjct: 1395 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGH 1454
Query: 948 PGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPT-----PGNLPVPSPMSPSSA 1002
PG L P G++ P ++ G P PG +P P P
Sbjct: 1455 PGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1514
Query: 1003 SISSFHGDESDSISSPGWPKTPSSP 1027
S+ + PG P +P P
Sbjct: 1515 KGSTGPAGQKGDSGLPGPPGSPGPP 1539
Score = 88.2 bits (217), Expect = 8e-17
Identities = 205/839 (24%), Positives = 260/839 (30%), Gaps = 163/839 (19%)
Query: 67 QQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGD 126
+ ++ + P S N G G A + HG A G+ G P + +PG
Sbjct: 385 EYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHG------AYGEKGQKGEPAVVEPGM 438
Query: 127 EDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPG--GGGGPAAVPEFNNYYGSAAPAS- 183
+ PP PA G PGL Q P PG G GP P G P
Sbjct: 439 LVEGPPGPAGPA-GIMGPPGL------QGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGT 491
Query: 184 --------GGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNS 235
GG G + GP Q++ ++ A A G PG M
Sbjct: 492 MLMLPFRYGGDGSK-GPTI---SAQEAQAQAILQQARIALRGPPGPMGLT---------- 537
Query: 236 QCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGG 295
RPG GG G G G SG G G G G A GG
Sbjct: 538 --------GRPGP-VGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 588
Query: 296 GGGGYGGSSA--GY-GVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQ 352
G G G+ G+ G+ P +G GP G G G
Sbjct: 589 GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGE-----IGPRG 643
Query: 353 HPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAA 412
P A P LL P P P QP A G
Sbjct: 644 LPGEAGP--RGLL------------------GPRGTPGAPGQP------GMAGVDGPPGP 677
Query: 413 AGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYG 472
G +MG Q P Q P PG GP G P + +P L G
Sbjct: 678 KG-----NMGPQ---GEPGPPGQQGNPGPQGLPGPQGPI-----GPPGEKGPQGKPGLAG 724
Query: 473 M--GSNPHSQP-QQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQ 529
+ P P ++ G+ GPPGPQ PIG G A + + G+
Sbjct: 725 LPGADGPPGHPGKEGQSGEKGALGPPGPQG-PIGYPGPRGVKGADGVRGLKGSKGEKGED 783
Query: 530 GVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPG 589
G G+ +G + + + P+ + P + R P D G PG
Sbjct: 784 GFPGF--KGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 841
Query: 590 KPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPA---- 645
P + P G P G+ A+G ++G P
Sbjct: 842 LPGY--------------PGRQG-----PKGSTG-FPGFPGANGEKGARGVAGKPGPRGQ 881
Query: 646 QSPFSPHASPHLSSIPGGPSP-------SPVGSPVGSNQSRSGPISPASIPGSQMPPQPP 698
+ P P S G P P P G P + GP P PG + PP PP
Sbjct: 882 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPP--GERGPQGPQGPVGFPGPKGPPGPP 939
Query: 699 GSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQ----QTGP-SMSPHPSPGGQM 753
G HP E GF T GPQ +TGP HP P G
Sbjct: 940 GKDG-LPGHPG-----QRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 993
Query: 754 -HAGI-SSFQQSNSSGTYGPQ--MSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANN 809
G+ + + + G GPQ + GP G P G+P A PG+
Sbjct: 994 GEQGLPGAAGKEGAKGDPGPQGISGKDGPAG-LRGFPGERGLPGAQ---GAPGL------ 1043
Query: 810 QMHGQGPSQPCGAV-PLGRMPSAGMQNR-PFPGNMSSMTPSSPGMSQQGGPG-MGPPMP 865
G+GP P G V G SAG PG P P ++G PG GP P
Sbjct: 1044 -KGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPA-GEKGAPGEKGPQGP 1100
Score = 86.7 bits (213), Expect = 2e-16
Identities = 172/686 (25%), Positives = 205/686 (29%), Gaps = 114/686 (16%)
Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPP----LLSKPGDEDDA-------PP 132
G GG PGP E+ G G PPGPP L PG + PP
Sbjct: 904 GTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP 963
Query: 133 KMGE---PAGGRYEHPGLGALGTQQPP-----VAVPGGGG--GPAAVPEFNNYYGSAAPA 182
G P G E +G G PP +PG G G P G PA
Sbjct: 964 GPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA 1023
Query: 183 S--GGPGGRAGPCFDQHGGQQSPGM--GMMHSASAAAAGAPGSMDPLQNSHE-GYPNSQC 237
G PG R P G Q +PG+ G G+PG + G P
Sbjct: 1024 GLRGFPGERGLP-----GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR-- 1076
Query: 238 NHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGG 297
PG P G G G G G G G G G A A + G G
Sbjct: 1077 ---PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1133
Query: 298 GGYGGSSAGYGVLSSPRQQG-GGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSG 356
G GS G P G G + PG G G + G P
Sbjct: 1134 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP 1193
Query: 357 ATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQ-------PQSQAAAAGAAAG-- 407
P Q L P P + G P P P Q PQ + G+ G
Sbjct: 1194 PGPIGLQGLPGP-PGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1252
Query: 408 -----------GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSP----GTPGPT- 451
G AG+G K + A P AA + G PGP
Sbjct: 1253 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVG 1312
Query: 452 MGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGP--QRYPIGIQGRT- 508
G P +P + + G Q P P G GPPGP +R P G G
Sbjct: 1313 FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG 1372
Query: 509 ----PGAM--AGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHL-----PPQAQ 557
GA AG + P + P G QG +G +P P L P Q
Sbjct: 1373 RQGEKGAKGEAGAEGPPGKTGP-VGPQGPAG------------KPGPEGLRGIPGPVGEQ 1419
Query: 558 YLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDL 617
LP + Q P M G P + G+ H P L G I
Sbjct: 1420 GLPGAAGQD-GPPGPMGPPGLPGLKGDPGSKGEKGH--------------PGLIGLIGPP 1464
Query: 618 PTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQ 677
E GS ++GD P P P P +PG P N+
Sbjct: 1465 GEQGEKGDRGLPGTQGSPGAKGDGGIPG--PAGPLGPPGPPGLPGPQGPK-------GNK 1515
Query: 678 SRSGPISPASIPGSQMPPQPPGSQSE 703
+GP G PP PG E
Sbjct: 1516 GSTGPAGQKGDSGLPGPPGSPGPPGE 1541
Score = 78.6 bits (192), Expect = 7e-14
Identities = 152/620 (24%), Positives = 191/620 (30%), Gaps = 110/620 (17%)
Query: 82 LGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGR 141
L G G PGP + G A + G PGP P E AP + G P G
Sbjct: 1043 LKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG-PQGPA 1101
Query: 142 YEHPGLGALGTQQP--PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAG-----PCF 194
G +G P P PG G + E GP G G
Sbjct: 1102 GRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAP 1161
Query: 195 DQHGGQQSPG----MGMM-HSASAAAAGAPGSMDPL-QNSHEGYPNSQCNH-------YP 241
GG PG GM A G PG P+ G P + + P
Sbjct: 1162 GIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1221
Query: 242 GYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYG 301
G P G G G G G G GG G G A A G G G
Sbjct: 1222 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1281
Query: 302 GSSAGYGVLSSPRQQG----------GGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQN 351
G + G P +G G + PG G A GG + G++
Sbjct: 1282 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDK---GED 1338
Query: 352 QHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQA 411
P P P P S + PP PP + AA G++
Sbjct: 1339 GDPG-----------QPGP---------PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKG 1378
Query: 412 AAG-------MGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMV 464
A G G +G Q A P + P G PG PM P
Sbjct: 1379 AKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP-- 1436
Query: 465 MKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQ-----RYPIGIQGRTPGAMAGMQYPQ 519
P L G+ +P S+ ++ P G GPPG Q R G QG +PGA P
Sbjct: 1437 ---PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQG-SPGAKGDGGIP- 1491
Query: 520 QQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP-PQAQYLPSQSQQRYQPQQDMSQEGY 578
G G G P PP LP PQ P ++ P Q+G
Sbjct: 1492 -------GPAGPLG------------PPGPPGLPGPQG---PKGNKGSTGP---AGQKGD 1526
Query: 579 GTRSQPPLAPGKPNH--EDLNLIQQER-----PSSLPDLSGSIDDLPTGTEATLSSAVSA 631
PP +PG P + L ++ ++ D +I D G E S S
Sbjct: 1527 SGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSL 1586
Query: 632 SGSTS----SQGDQSNPAQS 647
G Q+NPA++
Sbjct: 1587 KQDIEHMKFPMGTQTNPART 1606
Score = 40.4 bits (93), Expect = 0.020
Identities = 101/427 (23%), Positives = 139/427 (32%), Gaps = 74/427 (17%)
Query: 601 QERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSI 660
+++P+S P+ +P T+ T +S ++ G+ +G + PA +
Sbjct: 390 EDKPTSPPNEEFG-PGVPAETDITETS-INGHGAYGEKGQKGEPAVV----EPGMLVEGP 443
Query: 661 PGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMP------------PQPPGSQ------- 701
PG P+ + P G GP P PG + P P PPG+
Sbjct: 444 PGPAGPAGIMGPPGLQ----GPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRY 499
Query: 702 -SESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGP-SMSPHPSPGGQMHAGISS 759
+ S P +S QE A Q+ ++A GP GP ++ P P G G S
Sbjct: 500 GGDGSKGPTIS----AQEAQAQAILQQ-ARIALRGP--PGPMGLTGRPGPVG----GPGS 548
Query: 760 FQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVP-SASYSGPGPGMGISANNQMHGQGPSQ 818
SG GPQ GP+G PP +G P G G G+ G
Sbjct: 549 SGAKGESGDPGPQ----GPRG-VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD 603
Query: 819 PCGAVP--LGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAA 876
+P G G Q P P M + +G PG P + + A
Sbjct: 604 GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAP 663
Query: 877 AVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSS 936
Q G M G P Q L Q P + P
Sbjct: 664 G--QPGMAGVDGPPGPKGNMGPQG--EPGPPGQQGNPGPQGLPGPQGP---IGPPGEKGP 716
Query: 937 AASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTP-GNLPVPS 995
GLA + PG ADG G P E +S +G PP P G + P
Sbjct: 717 QGKPGLAGL--PG---------ADG-PPGHPGKEGQS----GEKGALGPPGPQGPIGYPG 760
Query: 996 PMSPSSA 1002
P A
Sbjct: 761 PRGVKGA 767
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 104 bits (260), Expect = 8e-22
Identities = 239/1039 (23%), Positives = 336/1039 (32%), Gaps = 146/1039 (14%)
Query: 102 GGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEH-PGLGALGTQQPPVAVP 160
G +GGQ G P S P + + G G+ ++ G G+ Q
Sbjct: 324 GQGHGCVSGGQPSGCGQPE-SNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQ 382
Query: 161 GGGGGPAAVPEFNNYYGSAAPASG-------------GPGGRAGPCFDQHGG--QQSPGM 205
G GG + + YGS S G G F+QHG QS G
Sbjct: 383 YGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGF 442
Query: 206 GMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGG-GGGGGGSGG 264
S G HE S + GY + G+ G G G G GSG
Sbjct: 443 EQHVCGSGQTCG----------QHE----STSSQSLGYDQHGSSSGKTSGFGQHGSGSGQ 488
Query: 265 GGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGV------LSSPRQQGG 318
G G G+G + + + ++G G G G S+G+G SS Q G
Sbjct: 489 SSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGS 548
Query: 319 GMMMGPGGG-------------GAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLL 365
G G G G S G G + +G QH SG+ Q
Sbjct: 549 GSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGS----GQSS 604
Query: 366 TSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQ--------AAAAGAAAGGQQAAAGMGL 417
RS SY ++SS S+ Q S+ + + + G Q +G G
Sbjct: 605 GFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQ 664
Query: 418 GKDMGAQYAAASPAWAAAQQRSHPAMSP-GTPGPTMGRSQGSPMDPMVMKRPQLYGMGSN 476
G + + + Q S S G G G SQ S Q G G +
Sbjct: 665 SSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHG--FGSSQSSGYGQHGSSSGQTSGFGQH 722
Query: 477 PHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGM-QYPQQQMPPQYGQQG----- 530
S Q SS G +G Q G G G +G Q+ + YGQ
Sbjct: 723 ELSSGQSSS---FGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQ 779
Query: 531 VSGYCQQGQQ-------------------PYYSQQPQP----PHLPPQAQYLPSQSQQRY 567
SGY Q G + Y S Q H Q +
Sbjct: 780 SSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESR 839
Query: 568 QPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSS 627
Q Q G G+ + + Q R SS +G +
Sbjct: 840 SHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQ 899
Query: 628 AVSASGSTSSQGD-QSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPA 686
+ SG S G +S QS + H S S G S G G Q RSG
Sbjct: 900 HGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSG----- 954
Query: 687 SIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPH 746
G GS S SS +S + GF R+ Q + YG +G S S
Sbjct: 955 --SGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQ-SNYGQHGSGSSQSSG 1011
Query: 747 PSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGIS 806
G + F Q SS Q+G + S G S SG G S
Sbjct: 1012 YGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRS 1071
Query: 807 ANNQ--MHGQGPSQPCGAVPLGR---MPSAGMQNRPFPGNMSSMTPSSPGMSQ-----QG 856
+ HG G SQ G G S Q+RP G S G Q Q
Sbjct: 1072 RQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQH 1131
Query: 857 GPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSS 916
G G G + + ++ Q S+QS S G ++SG ++S + Q ++ S
Sbjct: 1132 GSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQS---SGCGQHESGSGPTTS-FGQHVSGSD 1187
Query: 917 SLMNTQAPPYSMAPAMVNSSAASVGLADM---------MSPGES-KLPLPLKADGKEEGT 966
+ +S + ++ S S G + GES ++ G++E T
Sbjct: 1188 N--------FSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQETT 1239
Query: 967 -PQPESKSKDSYSSQGIS-QPPTPGNLPVPSPMSPSSAS-----ISSFHGDESDSISSPG 1019
Q + ++ S S QG S Q + S S +S S +S H + + +
Sbjct: 1240 HGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSH 1299
Query: 1020 WPKTPSSPKSSSSTTTGEK 1038
+PK+ S+ + TT G++
Sbjct: 1300 YPKSGSTVRRRQGTTHGQR 1318
Score = 92.8 bits (229), Expect = 3e-18
Identities = 226/1032 (21%), Positives = 326/1032 (31%), Gaps = 147/1032 (14%)
Query: 60 QQQQQQQQQQQQQQHPISNNNSLG--------GAGGGAPQPGPDMEQP----QHGGAKDS 107
Q + Q QH S+ + G G G Q G Q QHG
Sbjct: 455 QHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQ 514
Query: 108 AAG-GQ-ADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGG 165
++G GQ G + G+ G + G G G+++ G G
Sbjct: 515 SSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETS-GFGQHGLG 573
Query: 166 PAAVPEFNNYYGSAAPASG----GPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGS 221
F Y + +SG G G F QH + HS+ ++ + G
Sbjct: 574 SGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQ 633
Query: 222 MDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAV 281
Q S G S + G+ + G+G G G G G G G +G +
Sbjct: 634 HGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSY 693
Query: 282 AAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAA 341
++ ++G G G G ++G+G + G G G+ S + G
Sbjct: 694 GQHGFGSSQSSGYGQHGSSSGQTSGFG----QHELSSGQSSSFGQHGSGSGQSSGFGQHG 749
Query: 342 GGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAA 401
G + +G QH S + + +S S YG +S S SQ+
Sbjct: 750 SGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGS---SQSTG 806
Query: 402 AGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMD 461
G G +AG G Q S + + RSH + S G G G SQ S
Sbjct: 807 FGQYGSGSGQSAGFGQHGSGSGQ----SSGFGQHESRSHQS-SYGQHGS--GSSQSSGYG 859
Query: 462 PMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGM-QYPQQ 520
Q G G + S Q S G +G Q G G G +G Q+ +
Sbjct: 860 QHGSSSGQTSGFGQHRSSSGQYSG---FGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESR 916
Query: 521 QMPPQYGQQGV-----SGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQ 575
YGQ G SGY Q G S S Q + Q S
Sbjct: 917 SHQSSYGQHGSGSSQSSGYGQHG----------------------SSSGQTFGFGQHRSG 954
Query: 576 EGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGST 635
G + G H SGS G + S SG +
Sbjct: 955 SGQSS--------GFGQHG----------------SGS------GQSSGFGQHESGSGKS 984
Query: 636 SSQGD-QSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMP 694
S G +S +QS + H S S G S G G Q RS G
Sbjct: 985 SGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSS-------GQYSG 1037
Query: 695 PQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSP----HPSPG 750
GS S+ SS + Q GF R+ Q + YG +G S S H S
Sbjct: 1038 FGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQ-SSYGQHGSGSSQSSGYGQHGSNS 1096
Query: 751 GQMHAGISSFQ----QSNSSGTYGP---QMSQYGPQGN-------YSRPPAYSGVPSASY 796
GQ +G + QS+ G YG Q S +G G+ +++ SG S
Sbjct: 1097 GQT-SGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQ 1155
Query: 797 SGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQG 856
G G G GP+ G +G N G S + S G Q G
Sbjct: 1156 HGTGSSQSSGCGQHESGSGPTTSFG------QHVSGSDNFSSSGQHISDSGQSTGFGQYG 1209
Query: 857 GPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSS 916
G G ++Q+ + ++ RQ + G + S S Q S
Sbjct: 1210 S-GSGQSTGLGQGESQQV------ESGSTVHGRQETTHGQTINTTRHSQSGQGQSTQTGS 1262
Query: 917 SLMNTQAPPYS-MAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKD 975
+ + S + + V+S + + + S P + +GT +
Sbjct: 1263 RVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTT 1322
Query: 976 SYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSSPK---SSSS 1032
+ G Q G S +S H D +DS G P S + S +
Sbjct: 1323 RHGHSGHGQSTQTG--------SRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAG 1374
Query: 1033 TTTGEKITKVYE 1044
+ GE + V+E
Sbjct: 1375 SQHGESESTVHE 1386
Score = 82.4 bits (202), Expect = 5e-15
Identities = 177/821 (21%), Positives = 263/821 (32%), Gaps = 118/821 (14%)
Query: 34 HHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPG 93
H H + H + Q Q Q + ++S G G G+ G
Sbjct: 684 HESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGS---G 740
Query: 94 PDMEQPQHGGAKDSAAG-GQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGT 152
QHG ++G GQ + S+ G G+ + G + G G G+
Sbjct: 741 QSSGFGQHGSGSGQSSGFGQHE-------SRSGQSS-----YGQHSSGSSQSSGYGQHGS 788
Query: 153 QQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG----GPGGRAGPCFDQHGG---QQSPGM 205
+Q G G + F Y + ++G G G F QH Q S G
Sbjct: 789 RQTS-GFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQ 847
Query: 206 GMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGG 265
S+ ++ G GS Q S G S Y G+ + G+G G G G G G
Sbjct: 848 HGSGSSQSSGYGQHGSSSG-QTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQ 906
Query: 266 GGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPG 325
G G + + + ++ ++G G G G + G+G + G G G G
Sbjct: 907 YSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFG----QHRSGSGQSSGFG 962
Query: 326 GGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSP 385
G+ S + G G + +G QH S ++ + S S YG ++ S
Sbjct: 963 QHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYG----QHGSS 1018
Query: 386 SAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSP 445
S Q +S ++G +G Q +G G + + Q S S
Sbjct: 1019 SGQTTGFGQHRS---SSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSS 1075
Query: 446 -GTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGI 504
G G G SQ S Q G G + Q S G YG Q G
Sbjct: 1076 YGQHGS--GSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSG---FGQYGSGSGQSSGFGQ 1130
Query: 505 QGRTPGAMAGM-QYPQQQMPPQYGQQGVS-------GYCQQGQQPYYS---QQPQPPHLP 553
G G +G Q+ + YGQ G G + G P S +
Sbjct: 1131 HGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFS 1190
Query: 554 PQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLP----- 608
Q++ Q Q G G+ L G+ + R +
Sbjct: 1191 SSGQHISDSGQST-----GFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQETTHGQTIN 1245
Query: 609 ----DLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGP 664
SG TG+ T S S ++ S+ S S S H+ + G
Sbjct: 1246 TTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSE------VHSKVSHRHSEHIHTQAGSH 1299
Query: 665 SP---SPVGSPVGSNQSRSGPISPASIPG----SQMPPQPPGSQ-------SESSSHPAL 710
P S V G+ + G + G +Q + G Q ++S H +
Sbjct: 1300 YPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGV 1359
Query: 711 SQSPMPQERGF-MAGTQRNP----------------------------QMAQYGPQQTGP 741
S P QE+ AG+Q Q Q G + TG
Sbjct: 1360 SHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGHGQSTQRGSRTTGR 1419
Query: 742 SMSPHP-SPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGN 781
S H S ++H+G S QS T+G SQ+G G+
Sbjct: 1420 RGSGHSESSDSEVHSGGSHRPQSQEQ-THGQAGSQHGESGS 1459
Score = 34.3 bits (77), Expect = 1.4
Identities = 43/151 (28%), Positives = 57/151 (37%), Gaps = 23/151 (15%)
Query: 1264 FGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQ---RQQFPYG--ASYD 1318
FG G S F GQ + S Q Y Q SG+ + G GQ RQ +G S
Sbjct: 745 FGQHGSGSGQSSGF---GQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGS 801
Query: 1319 RRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQY 1378
+ +GQ G G +G +G H G Q + +H ++ H+
Sbjct: 802 SQSTGFGQYGSGSGQSAG---FGQHGSG-SGQSSGFGQH-------ESRSHQSSYGQHGS 850
Query: 1379 SSQQQEMYNQYG---GSYSG-PDRRPIQGQY 1405
S Q Y Q+G G SG R GQY
Sbjct: 851 GSSQSSGYGQHGSSSGQTSGFGQHRSSSGQY 881
Score = 34.3 bits (77), Expect = 1.4
Identities = 34/129 (26%), Positives = 43/129 (33%), Gaps = 7/129 (5%)
Query: 1264 FGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEP 1323
FG G S F GQ + S Q Y Q SG+ + G GQ S +H
Sbjct: 820 FGQHGSGSGQSSGF---GQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRS 876
Query: 1324 YGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQ 1383
QY G GQ G Q + Q G ++ H+ S Q
Sbjct: 877 SSGQYSG----FGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQS 932
Query: 1384 EMYNQYGGS 1392
Y Q+G S
Sbjct: 933 SGYGQHGSS 941
Score = 34.3 bits (77), Expect = 1.4
Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 9/78 (11%)
Query: 1264 FGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEP 1323
FG G S F GQ + S Q Y Q SG+ + G GQ S +
Sbjct: 1051 FGQHGTGSGQSSGF---GQYESRSRQSSYGQHGSGSSQSSGYGQH------GSNSGQTSG 1101
Query: 1324 YGQQYPGQGPPSGQPPYG 1341
+GQ PG G SG YG
Sbjct: 1102 FGQHRPGSGQSSGFGQYG 1119
Score = 33.9 bits (76), Expect = 1.8
Identities = 53/208 (25%), Positives = 60/208 (28%), Gaps = 41/208 (19%)
Query: 1264 FGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEP 1323
FG V G S F GQ + S Q Y Q G G Q YG R
Sbjct: 518 FGQHGSVSGQSSGF---GQHESRSRQSSYGQH--------GSGSSQSSGYGQYGSRETSG 566
Query: 1324 YGQQYPGQGPPSGQPPYG---GHQPGLYPQ------------------QPNYKRHMDGM- 1361
+GQ G G +G YG G G Q +Y +H G
Sbjct: 567 FGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSS 626
Query: 1362 ----YGPPAKRHEGDMYNMQYSSQQQEMYNQYG---GSYSGPDRRPI-QGQYPYPYSRER 1413
YG R S Q + QYG G SG + GQ E
Sbjct: 627 QSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHES 686
Query: 1414 MQGPGQIQTHGIPPQMMGGPLQSSSSEG 1441
G HG G Q SS G
Sbjct: 687 RSGHSSYGQHGFGSSQSSGYGQHGSSSG 714
Score = 33.5 bits (75), Expect = 2.4
Identities = 38/144 (26%), Positives = 54/144 (37%), Gaps = 29/144 (20%)
Query: 730 QMAQYGPQQTGPSMSPHP-SPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAY 788
Q Q G + G S H S ++H+G+S ++S TYG SQ+G G
Sbjct: 2089 QSTQRGSRTAGRRGSGHSESSDSEVHSGVS---HTHSGHTYGQARSQHGESG-------- 2137
Query: 789 SGVPSASYSGPGPGMGISANNQMHGQ---GPSQPCGAVPLGRMPSAGMQNR--------- 836
SA + G G + + HGQ G S G+ GR S+ ++
Sbjct: 2138 ----SAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEAS 2193
Query: 837 -PFPGNMSSMTPSSPGMSQQGGPG 859
G+ S S G S G G
Sbjct: 2194 PTHSGHTHSQAGSRHGQSGSSGHG 2217
Score = 33.1 bits (74), Expect = 3.1
Identities = 44/151 (29%), Positives = 54/151 (35%), Gaps = 23/151 (15%)
Query: 1264 FGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEP 1323
FG G S F GQ + S Q Y Q SG+ + G GQ S +
Sbjct: 974 FGQHESGSGKSSGF---GQHESRSSQSNYGQHGSGSSQSSGYGQH------GSSSGQTTG 1024
Query: 1324 YGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGM-----YGPPAKRHEGDMYNMQY 1378
+GQ G SG +G H G Q + +H G +G R Y
Sbjct: 1025 FGQHRSSSGQYSG---FGQHGSG-SDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHG 1080
Query: 1379 S-SQQQEMYNQYG---GSYSG-PDRRPIQGQ 1404
S S Q Y Q+G G SG RP GQ
Sbjct: 1081 SGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQ 1111
Score = 32.0 bits (71), Expect = 7.0
Identities = 48/178 (26%), Positives = 57/178 (32%), Gaps = 33/178 (18%)
Query: 1286 SSMQDMYNQ--SPSGAMSNLGM-----GQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQP 1338
SS Y Q S SG S G GQ F S + +GQ G G SG
Sbjct: 700 SSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSG-- 757
Query: 1339 PYGGHQPGLYPQQPNYKRHMDGM-----YGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSY 1393
+G H+ Q +Y +H G YG R S Q + QYG
Sbjct: 758 -FGQHES--RSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGS 814
Query: 1394 ----------SGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEG 1441
SG + GQ+ SR GQ HG G Q SS G
Sbjct: 815 GQSAGFGQHGSGSGQSSGFGQHE---SRSHQSSYGQ---HGSGSSQSSGYGQHGSSSG 866
Score = 32.0 bits (71), Expect = 7.0
Identities = 49/196 (25%), Positives = 63/196 (32%), Gaps = 44/196 (22%)
Query: 1281 GQMPNSSMQDMYNQSPSGAMSNLGMGQR-----QQFPYG---------------ASYDRR 1320
GQ + S Q Y Q SG+ + G GQ Q F +G S +
Sbjct: 911 GQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQ 970
Query: 1321 HEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGM-----YGPPAKRHEGDMYN 1375
+GQ G G SG +G H+ Q NY +H G YG G
Sbjct: 971 SSGFGQHESGSGKSSG---FGQHES--RSSQSNYGQHGSGSSQSSGYGQHGS-SSGQTTG 1024
Query: 1376 MQYSSQQQEMYNQYGGSYSGPDRRPIQGQ----------YPYPYSRERMQGPGQIQTHGI 1425
Y+ +G SG D+ GQ + SR R GQ HG
Sbjct: 1025 FGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQ---HGS 1081
Query: 1426 PPQMMGGPLQSSSSEG 1441
G Q S+ G
Sbjct: 1082 GSSQSSGYGQHGSNSG 1097
>gi|55956910 meningioma 1 [Homo sapiens]
Length = 1320
Score = 104 bits (260), Expect = 8e-22
Identities = 241/1019 (23%), Positives = 332/1019 (32%), Gaps = 237/1019 (23%)
Query: 115 PPGP--PLLSKPGDEDDAPPKMG---EPAGGRYE-HPGLGALGTQQPPVAVPGGGGGPAA 168
PPGP P +S G+ PP +G EP G H L A G Q PV
Sbjct: 44 PPGPVDPAMSALGE----PPILGMNMEPYGFHARGHSELHAGGLQAQPV----------- 88
Query: 169 VPEFNNYYGSAAPASGGPGG----RAGPCFDQHGGQQSPGMGMMHSAS----AAAAGAPG 220
+ ++G P G PG + P F + G PG +H AAG G
Sbjct: 89 ----HGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLG 144
Query: 221 SMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGG------------SGGGGGG 268
S P +E SQ G RPG G +
Sbjct: 145 SQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFH 204
Query: 269 GGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSP-------------RQ 315
G + G+ + ++ A G + +G+ + SP RQ
Sbjct: 205 GLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQ 264
Query: 316 QGGGMMMG----PGGGGAASLSKAAAGSAAGG-----------------FQRFAGQNQHP 354
GG G P G LSK A F+RF+G + P
Sbjct: 265 VPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMP 324
Query: 355 SGATPTLNQ---LLTSPS---PMMRSYGGSYPEYSSPSAPPP--------PPSQPQSQAA 400
G P++ L+ P P + P P PP PP+ P+ Q
Sbjct: 325 VGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQG 384
Query: 401 AAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQ---- 456
AG +GG Q M + +Y + S P S P P +Q
Sbjct: 385 EAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQH 444
Query: 457 -GSPMDPMVMKRPQLYGMGS------------------NPHSQPQQSSPYPG--GSYGPP 495
+P V KRP+ GS + H P S YPG G + PP
Sbjct: 445 FDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSP---SAYPGLPGEFTPP 501
Query: 496 GPQRYPIG--IQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLP 553
P +P G +Q P + Q QQQ Q QQ QQ QQ QQ Q +
Sbjct: 502 VPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQ------QQQQQQQQQQQQQRQNAA 555
Query: 554 PQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGS 613
+ + S++QQ+ Q +++Q G+ PG G
Sbjct: 556 LMIKQMASRNQQQRLRQPNLAQLGH---------PGDVGQ-----------------GGL 589
Query: 614 IDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPV 673
+ P G A + GST + + Q+P S S GP P P G +
Sbjct: 590 VHGGPVGGLAQ-PNFEREGGSTGAGRLGTFEQQAPHLAQESAWFS----GPHPPP-GDLL 643
Query: 674 GSNQSRSG-PISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMA 732
SG P S PP PPG L + P+ QE M G P +
Sbjct: 644 PRRMGGSGLPADCGPHDPSLAPPPPPGGSG------VLFRGPL-QEPMRMPGEGHVPAL- 695
Query: 733 QYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVP 792
PSPG Q + Q S P A G+P
Sbjct: 696 --------------PSPGLQFGGSLGGLGQLQS-------------------PGAGVGLP 722
Query: 793 SASYS--GPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSP 850
SA+ P P SA + GQ P P GA AG Q+ P G + PS+
Sbjct: 723 SAASERRPPPPDFATSA---LGGQ-PGFPFGA--------AGRQSTPHSGPGVNSPPSAG 770
Query: 851 GMSQQGGPGMG----PPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSS 906
G G G G PP P + +Q +A+ + A + + ++ S + +A+ S
Sbjct: 771 GGGGSSGGGGGGGAYPPQPDF-QPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALS 829
Query: 907 PYSQPM------NNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKAD 960
Q M N + N + PP N + G A +PG P
Sbjct: 830 TACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETD---GAAVAGNPGSDYFP-----G 881
Query: 961 GKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPG 1019
G G P P S S S S PP P + +SP + ++ S G++ +S G
Sbjct: 882 GTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSP-NYTLESTSGNDGKPVSGGG 939
Score = 95.1 bits (235), Expect = 7e-19
Identities = 168/663 (25%), Positives = 217/663 (32%), Gaps = 145/663 (21%)
Query: 40 HHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSL----------------- 82
H H +LQQQ Q QQQQQQQQQQQQQQQQQQ N +L
Sbjct: 514 HPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQP 573
Query: 83 ------------------GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKP 124
GG GG QP + E GG+ + G + P L +
Sbjct: 574 NLAQLGHPGDVGQGGLVHGGPVGGLAQPNFERE----GGSTGAGRLGTFEQQAPHLAQES 629
Query: 125 GDEDDAPPKMGEPAGGRYEHPGLGA-LGTQQP---PVAVPGGGG----GPAAVPEFNNYY 176
P G+ R GL A G P P PGG G GP P
Sbjct: 630 AWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGE 689
Query: 177 GSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQ 236
G PA PG + G G QSPG G + SAA+ P D ++ G P
Sbjct: 690 GH-VPALPSPGLQFGGSLGGLGQLQSPGAG-VGLPSAASERRPPPPDFATSALGGQPGFP 747
Query: 237 CNHYPGYSRPGAGGGGGG--GGGGGGGSGGGGGGGGA------------------GAGGA 276
S P +G G GGGGGS GGGGGGGA GA
Sbjct: 748 FGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSL 807
Query: 277 GA----------------GAVAAAAAAAAAAAGG--------------GGGGGYGGSSAG 306
G+ A++ A A+ G G + G
Sbjct: 808 GSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDG 867
Query: 307 YGVLSSPRQQ---GGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQ 363
V +P GG PG GG + S ++GS A G Q S +P
Sbjct: 868 AAVAGNPGSDYFPGGTAPGAPGPGGPSGTS--SSGSKASGPPNPPAQGDGTS-LSPNYTL 924
Query: 364 LLTSPSPMMRSYGGS-------------------YPEYSSPSAPPPPPSQPQSQAAAAGA 404
TS + GG + +YS+ P Q A+GA
Sbjct: 925 ESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGA 984
Query: 405 AAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQ---RSHPAMSPGTPG--------PTMG 453
A GG ++AG G + A SP+W + P + G P +G
Sbjct: 985 AVGG--SSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVG 1042
Query: 454 RSQGSPMDPMVMKRPQLYGMGSNPHSQPQQS-SPYPGGS--YGPPGPQRYPIGIQGRTPG 510
+ ++ NP + + S SP GS P G G + P
Sbjct: 1043 EFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPA 1102
Query: 511 AMAGMQYPQQQMPPQYGQQGVSGY-----CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQ 565
G+ P YG G G+ +Q + P S PP + L +Q Q
Sbjct: 1103 LGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQL 1162
Query: 566 RYQ 568
+ Q
Sbjct: 1163 QRQ 1165
Score = 68.2 bits (165), Expect = 9e-11
Identities = 125/504 (24%), Positives = 179/504 (35%), Gaps = 69/504 (13%)
Query: 83 GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRY 142
GG+ GG Q ++ P G SAA + PP S G + P A GR
Sbjct: 703 GGSLGGLGQ----LQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFP----FGAAGRQ 754
Query: 143 EHPGLGALGTQQPPVA-----VPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQH 197
P G G PP A GGGGG A P ++ S ++ G + F++
Sbjct: 755 STPHSGP-GVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKP 813
Query: 198 GGQQSP-GMGMMHSASAA------AAGAP-------------GSMDPLQNSHEGYP---N 234
+ + G + + S A + GAP G QN +G N
Sbjct: 814 SSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGN 873
Query: 235 SQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG----GAGAGGAGAGAVAAAAAAAAA 290
+++PG + PGA G GG G GS G G G + + + +
Sbjct: 874 PGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGK 933
Query: 291 AAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLS---KAAAGSAAGGFQRF 347
GGGG G G G +S P P GGA +S + A+G+A GG
Sbjct: 934 PVSGGGGRGRGRRKRDSGHVS-PGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSS-- 990
Query: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407
AG+ + GA + LTSPS G P +S +++
Sbjct: 991 AGETR---GAPTPHEKALTSPS---WGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEF 1044
Query: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467
+ +D + + A A + SP P +G + P P
Sbjct: 1045 ASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAP----- 1099
Query: 468 PQLYGMG--SNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQ 525
P G+G SN S P Y GG G PG P Q RTP + +G P + P +
Sbjct: 1100 PPALGLGIMSNSTSTPDS---YGGG--GGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLE 1154
Query: 526 YGQQGVSGYCQQGQQPYYSQQPQP 549
Q + Q +Q + + QP
Sbjct: 1155 ILQAQI----QLQRQQFSISEDQP 1174
Score = 57.8 bits (138), Expect = 1e-07
Identities = 235/1074 (21%), Positives = 314/1074 (29%), Gaps = 206/1074 (19%)
Query: 46 HALQQQLNQFQQQQQQQQQQQQQQQQQQHP---ISNNNSL------------GGAGGGAP 90
H L Q Q QQQ QQ QQQ P + NS G GG
Sbjct: 335 HPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQ 394
Query: 91 QPGP-------DMEQPQHGGAKDSA------AGGQADPPGPPLLSKPGDEDDAPPKMGEP 137
GP E P H S PP ++ DAPP M
Sbjct: 395 DGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVA 454
Query: 138 AGGRYEHPGL---------------GALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPA 182
R++ PG GAL P A PG G P + + S P
Sbjct: 455 KRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPG--EFTPPVPDSFPSGPPL 512
Query: 183 SG-GPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCN-HY 240
P ++ Q QQ L N Q
Sbjct: 513 QHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQ 572
Query: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGG-------GGGAGAGGAGAGAVAAAAAAAAAAAG 293
P ++ G G G GG GG GG GG GAG G A A +A
Sbjct: 573 PNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESA-- 630
Query: 294 GGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQH 353
+ G G L R G G+ P G S A G F G Q
Sbjct: 631 -----WFSGPHPPPGDLLPRRMGGSGL---PADCGPHDPSLAPPPPPGGSGVLFRGPLQE 682
Query: 354 PSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAA 413
P P + PSP ++ +GGS G Q A
Sbjct: 683 PM-RMPGEGHVPALPSPGLQ-FGGSL-----------------------GGLGQLQSPGA 717
Query: 414 GMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGM 473
G+GL AA+++R P P +G G P G
Sbjct: 718 GVGLPS-------------AASERRPPP---PDFATSALGGQPGFPFGAA--------GR 753
Query: 474 GSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQ--MPPQYGQQGV 531
S PHS P +SP G G G + G G YP Q P Q
Sbjct: 754 QSTPHSGPGVNSPPSAGGGG------------GSSGGGGGGGAYPPQPDFQPSQRTSASK 801
Query: 532 SGYCQQGQQPYYSQQPQPPHLPPQA--QYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPG 589
G G +++ +L Q+ L + Q + + PP
Sbjct: 802 LGALSLGS---FNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKR 858
Query: 590 KPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSP- 648
K L Q E + + D P GT SG++SS S P P
Sbjct: 859 K-------LSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPA 911
Query: 649 ------FSPHAS-PHLSSIPGGPSPSPVGSPVGSNQSRSGPISP--------ASIPGSQM 693
SP+ + S G P G G + SG +SP A+
Sbjct: 912 QGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGA 971
Query: 694 PPQPPGSQSES------SSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQT------GP 741
P PG Q S SS +P P E+ + + G Q G
Sbjct: 972 PGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGG 1031
Query: 742 SMSPHPSPGGQMHAGISSFQQSNSSGTYGPQ----MSQYGPQG--NYSRPPAYSGVPSAS 795
+ S SP + F S +Y + S PQ SR P +G P
Sbjct: 1032 AKSDSSSPN------VGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLP 1085
Query: 796 YSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQ 855
G G G GP P A+ LG M ++ + G P +PG+ Q
Sbjct: 1086 PRGVGAGE----------HGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQV 1135
Query: 856 GGP--GMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMN 913
P G P P E + A Q +Q S GL +
Sbjct: 1136 RTPTSSSGAPPP------DEIHPLEILQAQIQLQRQQFSISEDQPLGLKGGKK--GECAV 1187
Query: 914 NSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPL------KADGKEEGTP 967
+S N + S V S+ +++ L +M+ + +P AD + P
Sbjct: 1188 GASGAQNGDSELGSCCSEAVKSAMSTIDLDSLMAEHSAAWYMPADKALVDSADDDKTLAP 1247
Query: 968 QPESKSKDSYSSQGISQPPTPGNLPVP-SPMSPSSASISSFHGDESDSISSPGW 1020
++K ++ S + P + P S + S + GD S P W
Sbjct: 1248 WEKAKPQNPNSKEAHDLPANKASASQPGSHLQCLSVHCTDDVGDAKARASVPTW 1301
Score = 56.2 bits (134), Expect = 3e-07
Identities = 109/462 (23%), Positives = 164/462 (35%), Gaps = 81/462 (17%)
Query: 1161 QPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHD 1220
Q P + GS Q G N PG AS HG GG + +
Sbjct: 95 QQPHHGHPGSHHPHQHHPHFGGNFGGPDPG-------ASCLHGGRLLGYGGAAGGLGSQP 147
Query: 1221 PFSD----VSDSSFPKRNSMTPNAP------YQQGMS---MPDVMGRMPYEPNKDP-FGG 1266
PF++ +++S P+ S P P + G S +P + PN+ F G
Sbjct: 148 PFAEGYEHMAESQGPE--SFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHG 205
Query: 1267 MRKVPGSSEPFMTQGQMPNSSMQDM--YN---QSPSGAMSNLGMGQRQ-QFPYGASYDRR 1320
+ GS + ++ N D YN ++PSG + Q P+ A+
Sbjct: 206 LPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAA---- 261
Query: 1321 HEPYGQQYPGQG-PPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYS 1379
G+Q PG P + P GL K H PP ++ + Q
Sbjct: 262 ----GRQVPGGAFPGASAMPRAAGMVGLS------KMHAQ----PPQQQPQ----QQQQP 303
Query: 1380 SQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSS 1439
QQQ+ + + +SG + P+ G P SR + P Q PP P Q
Sbjct: 304 QQQQQQHGVFFERFSGARKMPV-GLEPSVGSRHPLMQPPQ---QAPPPPQQQPPQQPPQQ 359
Query: 1440 EGPQQNMWAARND-----MPYPYQNRQG-PGGPTQ--APPYPGMNRTDDMMVPDQRINHE 1491
+ P R + +P P Q G P G Q P P + + P R+ +
Sbjct: 360 QPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEY--PIHRLENR 417
Query: 1492 SQWPSH-----VSQRQPYMSSSASMQPITRPP------QPSYQTPPSLPNHISRAPSPAS 1540
S P + P + + +Q PP +P + P S + + +
Sbjct: 418 SMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSM 477
Query: 1541 FQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPP 1582
+L+N +SPS P LP + P VP S +GPP Q P
Sbjct: 478 HNGALDNHLSPSAYPGLPG----EFTPPVPDSFPSGPPLQHP 515
Score = 41.6 bits (96), Expect = 0.009
Identities = 33/102 (32%), Positives = 40/102 (39%), Gaps = 14/102 (13%)
Query: 58 QQQQQQQQQQQQQQQQHPISNNNSLG----------GAGGGAPQPGPDMEQPQHGGAKDS 107
QQQ QQQQQ QQQQQQH + G G P P + P +
Sbjct: 294 QQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPP 353
Query: 108 AAGGQADPPGPP-LLSKPGDEDDAPPKMGEPAGGRYEHPGLG 148
Q PP PP LL + ++ PP + P G P G
Sbjct: 354 QQPPQQQPPPPPGLLVR---QNSCPPALPRPQQGEAGTPSGG 392
Score = 36.2 bits (82), Expect = 0.37
Identities = 43/164 (26%), Positives = 70/164 (42%), Gaps = 18/164 (10%)
Query: 1201 PHGQMTPMQGGRS---STISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPY 1257
P G + P + G S + HDP ++ P + + P Q+ M MP G +P
Sbjct: 638 PPGDLLPRRMGGSGLPADCGPHDP--SLAPPPPPGGSGVLFRGPLQEPMRMPGE-GHVPA 694
Query: 1258 EPNKD-PFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGAS 1316
P+ FGG G + +P+++ + + P + +G + FP+GA+
Sbjct: 695 LPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASE---RRPPPPDFATSALGGQPGFPFGAA 751
Query: 1317 YDRRHEPYGQQYPG-QGPPS----GQPPYGGHQPGLYPQQPNYK 1355
R+ P+ PG PPS G GG G YP QP+++
Sbjct: 752 -GRQSTPHSG--PGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQ 792
Score = 33.1 bits (74), Expect = 3.1
Identities = 81/347 (23%), Positives = 117/347 (33%), Gaps = 83/347 (23%)
Query: 1299 AMSNLG----MGQRQQFPYG---ASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQ 1351
AMS LG +G + PYG + H Q P G GQ P+ GH +P Q
Sbjct: 51 AMSALGEPPILGMNME-PYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPHQ 109
Query: 1352 PNYKRHMDGMYGPP----AKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRP------- 1400
+ H G +G P + H G + YGG+ G +P
Sbjct: 110 --HHPHFGGNFGGPDPGASCLHGGRLLG-------------YGGAAGGLGSQPPFAEGYE 154
Query: 1401 --IQGQYPYPYSRERMQGPGQI--------QTHGIPPQMM---GGPLQSSSSEGPQQNMW 1447
+ Q P + +R PG + +H +P + P +++S G +
Sbjct: 155 HMAESQGPESFGPQR---PGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSG 211
Query: 1448 AARNDMPYPYQNRQGPGGPTQAPPYPGMNRTD--DMMVPDQRINHESQWPSHVSQRQ--- 1502
+ + + QG + YPG + DM P + E Q P + + RQ
Sbjct: 212 SDSHSLEPRRVTNQGAVDSLEY-NYPGEAPSGHFDMFSPS---DSEGQLPHYAAGRQVPG 267
Query: 1503 ------PYMSSSASM--------QPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENR 1548
M +A M QP + PQ Q H S R +
Sbjct: 268 GAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQH-GVFFERFSGARKMPVG 326
Query: 1549 MSPSKSPFLPSMKMQKVMPTVPTSQVTGPPP--QPPPIRREITFPPG 1593
+ PS P M+ + P P Q PP QPPP PPG
Sbjct: 327 LEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPP-------PPG 366
>gi|5453638 AT rich interactive domain 3B [Homo sapiens]
Length = 560
Score = 104 bits (259), Expect = 1e-21
Identities = 64/202 (31%), Positives = 107/202 (52%), Gaps = 6/202 (2%)
Query: 995 SPMSPSSASISSFHGDESDSISSPGWPKTPSSPKSSSSTTTGEKITKVYELGNEPERKLW 1054
S SPS ++ + + + + G K+YEL +PERK +
Sbjct: 162 SKASPSVSTAGQPNWNLDEQLKQNGGLAWSDDADGGRGREISRDFAKLYELDGDPERKEF 221
Query: 1055 VDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVG 1114
+D FM++RG+P++ +P + K+ LDL+ LY V E GGL ++ K WRE+ LN+
Sbjct: 222 LDDLFVFMQKRGTPINRIPIMAKQILDLYMLYKLVTEKGGLVEIINKKIWREITKGLNLP 281
Query: 1115 TS-SSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQG 1173
TS +SAA +L+ QY++YL+A+EC+ ++ P E+ + D ++ + P+ S SL G
Sbjct: 282 TSITSAAFTLRTQYMKYLYAYECE-KKALSSPAELQAAIDGNRR---EGRRPSYSSSLFG 337
Query: 1174 PQTPQSTGSNSMAEVPGDLKPP 1195
+P + + + A P L PP
Sbjct: 338 -YSPAAATAAAAAGAPALLSPP 358
>gi|62865637 AT rich interactive domain 3C (BRIGHT- like) [Homo
sapiens]
Length = 412
Score = 103 bits (258), Expect = 1e-21
Identities = 101/349 (28%), Positives = 161/349 (46%), Gaps = 30/349 (8%)
Query: 1010 DESDSISSPGWPKTPSSPKSSS------STTTGEKITKVYELGNEPERKLWVDRYLTFME 1063
+E+ S PG + PSSP S T E+ ++YEL +P+RK ++D +FM+
Sbjct: 70 EEAAEESRPG-AQGPSSPSSQPPGLHPHEWTYEEQFKQLYELDADPKRKEFLDDLFSFMQ 128
Query: 1064 ERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTS-SSAASS 1122
+RG+PV+ +P + K+ LDL+ L+ V GGL +V K WRE+ L++ T+ +SAA +
Sbjct: 129 KRGTPVNRVPIMAKQVLDLYALFRLVTAKGGLVEVINRKVWREVTRGLSLPTTITSAAFT 188
Query: 1123 LKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGS 1182
L+ QY++YL+ +EC+ R P E+ + D+ ++ + A L G P G+
Sbjct: 189 LRTQYMKYLYPYECE-TRALSSPGELQAAIDSNRREGRRQAYTAT--PLFGLAGPPPRGA 245
Query: 1183 NSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPN--A 1240
A PG P T +S Q G +S + H + +S S K S PN
Sbjct: 246 QDPALGPGPAPPATQSSPGPAQ------GSTSGLPAH-ACAQLSPSPIKKEESGIPNPCL 298
Query: 1241 PYQQGMSMPDVMGRM-PYEP--NKDPFGGMRKVPGSSEP--FMTQGQMP--NSSMQDMYN 1293
G+++ ++ P EP + G P P F+ +G++P + N
Sbjct: 299 ALPVGLALGPTREKLAPEEPPEKRAVLMGPMDPPRPCMPPSFLPRGKVPLREERLDGPLN 358
Query: 1294 QSPSGAMS-NLGMGQRQQFPYGASYDRRHEPYGQQYPGQ--GPPSGQPP 1339
+ SG S N+ + G + RR Q P PPS PP
Sbjct: 359 LAGSGISSINMALEINGVVYTGVLFARRQPVPASQGPTNPAPPPSTGPP 407
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 102 bits (255), Expect = 3e-21
Identities = 262/1111 (23%), Positives = 370/1111 (33%), Gaps = 250/1111 (22%)
Query: 440 HPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQR 499
+P + P TP P SQ MDP++ S H Q Q +P GS PP
Sbjct: 200 NPELQPRTPRPA---SQSDAMDPLL----------SGLHIQQQS---HPSGSLAPPHHPM 243
Query: 500 YPIGIQGR-TPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQ-----PYYSQQPQPPHL- 552
P+ + + P +Q QQQ Q QQ QQ QQ P QQ QP +
Sbjct: 244 QPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIR 303
Query: 553 ------------------------PPQAQY---------------LPSQSQQRYQPQQDM 573
PP AQ LP QQ+ Q + +
Sbjct: 304 PQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSL 363
Query: 574 SQEGYGTRSQPPLAPG--KPNHEDLNLIQQERPSS-----LPDLSGSIDDLPTGTEATLS 626
+ + PP G + + N Q P + L G +PT +
Sbjct: 364 ATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHL 423
Query: 627 SAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVG--SPVGSNQSRSGPIS 684
+ S + S SS Q +PA SP + P +P P G PV S+ R+ +
Sbjct: 424 TNKSPASSPSSF-QQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPV-SSPGRNPMVQ 481
Query: 685 PASIPGSQMP-PQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSM 743
++P + M Q P +Q S HP L P GF AG Q NP Q G + +
Sbjct: 482 QGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAG-QANPNFMQ-GQVPSTTAT 539
Query: 744 SPHPSPGGQMHAGISSFQQSNSSG----------TYGP----QMSQYGPQGNYSRPPA-Y 788
+P S Q+ A + Q + G ++GP Q S G GN + A
Sbjct: 540 TPGNSGAPQLQAN-QNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGT 598
Query: 789 SGVPSASYSG---------PGPGMGI------SANNQMHGQGPSQPCGAVPLGR---MPS 830
SGVP + S P MG+ S + QG P + L R MP
Sbjct: 599 SGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQ 658
Query: 831 AGMQNRPFPGNMSS----MTPSSPGMSQQGGPGMGPPMPTVNRKAQ---EAAAAVMQAAA 883
M P N+ MTP +SQQG M P + + Q + + Q
Sbjct: 659 GQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMT 718
Query: 884 NSAQSRQGSFPGMNQSGLMASSSPYSQ-PMNNS-----------SSLMNTQAPPYSMAPA 931
N Q + F NQS +M + + P N S M Q P + +P+
Sbjct: 719 NQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPS 778
Query: 932 MVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQ--GISQPPTPG 989
V V + PG P P A ++ G P + + S S +S T
Sbjct: 779 QVMGIQGQV----LRPPG----PSPHMA--QQHGDPATTANNDVSLSQMMPDVSIQQTNM 828
Query: 990 NLPVPSPMSPSSASISSFHGDESDSISSP--GWP--------KTPSSPKSSSSTTTGEKI 1039
P M +SAS + F G S ++P G P + P P + T T +
Sbjct: 829 VPPHVQAMQGNSASGNHFSG-HGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLL 887
Query: 1040 TKVYEL-----------------GNEPERKLWVDRYLTFMEERGSP---VSSLPAVGKKP 1079
+ + N+P++K + ++ +P + L + P
Sbjct: 888 VNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPP 947
Query: 1080 LDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIE 1139
L + G+ N K E + N G S Q + ++
Sbjct: 948 LPGEQ---------GINLDNSGPKLPEFS-NRPPGYPSQPVEQRPLQQMPP------QLM 991
Query: 1140 RGEEPPPEVFSTGDTKKQPKL----QPPSPANSGSLQGPQTPQSTGSNSMAE-------- 1187
+ PPP+ + QP+L QPP P+ S Q Q Q M +
Sbjct: 992 QHVAPPPQ---PPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRL 1048
Query: 1188 -VPGDLKPPTPASTPHGQMTPMQ--GGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQ 1244
V ++ PP P Q PMQ G +S+ P S V S +R M N P
Sbjct: 1049 PVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPAS-VPPSPDKQRMPMPVNTPLGS 1107
Query: 1245 GMSMPDVMGRMPYEPNKDPFGGMRKVP---GSSEPFMTQG--QMP-------NSSMQDMY 1292
S V P P+ P M +P GS P + G MP N M
Sbjct: 1108 N-SRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGP 1166
Query: 1293 NQSPSGAMSNLGMGQRQ------------QFPYGASYDRRHEP----------YGQQYPG 1330
PS + G +Q FP A+ + P Y Q P
Sbjct: 1167 KPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPN 1226
Query: 1331 QGPPSGQPPYGGHQP--------GLYPQQPN 1353
PPS +P P GL+P Q N
Sbjct: 1227 NRPPSTEPSEISLSPERLNASIAGLFPPQIN 1257
Score = 89.0 bits (219), Expect = 5e-17
Identities = 304/1374 (22%), Positives = 453/1374 (32%), Gaps = 262/1374 (19%)
Query: 48 LQQQLNQFQQQQQQQQQQQQQQQQQQ---------------------------------- 73
LQQQ Q QQQQQQQQQQQQQQQQQQ
Sbjct: 260 LQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWN 319
Query: 74 -------HPISNNNSLGGAGGG-----APQPGPDMEQPQHGGAKDSAAGGQADPPGPPLL 121
P SLG AP PGP +Q Q + + PP P
Sbjct: 320 QLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFG 379
Query: 122 SKPGDEDDAP-PKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180
S+ + P+M P G++ P + +L Q P VP P P N +++
Sbjct: 380 SQQASQAHTNFPQMSNP--GQFTAPQMKSL--QGGPSRVP----TPLQQPHLTNKSPASS 431
Query: 181 PASGGPGGRA-GPCFD---QHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQ 236
P+S G A P + Q G + P + +PG +P+ PN
Sbjct: 432 PSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPG-RNPMVQQGNVPPNFM 490
Query: 237 C------NHYPGYSRPGAGGGG---GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAA 287
N P PG GG G G + G G A
Sbjct: 491 VMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQ 550
Query: 288 AAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRF 347
A GG G G V P +MG G + +G
Sbjct: 551 ANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGI-HGNMNNQQAGTSGVPQVNLSNM 609
Query: 348 AGQNQH--PSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAA 405
GQ Q PS Q++ S M++ G P+ +P PQ Q +
Sbjct: 610 QGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQ--NPMILSRAQLMPQGQMMVNPPS 667
Query: 406 AGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSP-----GTPGPTMGRSQGSPM 460
+++G +P Q+ M+P G G + Q +PM
Sbjct: 668 -------------QNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVL--LQQNPM 712
Query: 461 DPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQ 520
+M Q+ G ++Q QS+ PG + GP G + G M+G PQQ
Sbjct: 713 IEQIMTN-QMQGNKQQFNTQ-NQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQ 770
Query: 521 ----QMPPQYGQQGVSGYCQQ--GQQPYYSQQPQPPHLPPQ-----AQYLPSQSQQR--- 566
P Q G+ G + G P+ +QQ P +Q +P S Q+
Sbjct: 771 GPVNNSPSQV--MGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNM 828
Query: 567 ----YQPQQDMSQ-----EGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDL 617
Q Q S G+G P + G PN ++ Q D++ + L
Sbjct: 829 VPPHVQAMQGNSASGNHFSGHGMSFNAPFS-GAPNGNQMSCGQNPGFPVNKDVTLTSPLL 887
Query: 618 PTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVG------- 670
++ +S+ + + + + P + P + P P G
Sbjct: 888 VNLLQSDISAGHFGVNNKQNNTNANKPKKKK-PPRKKKNSQQDLNTPDTRPAGLEEADQP 946
Query: 671 ---SPVGSNQSRSGPISP--------------ASIPGSQMPPQ------PPGSQSESSSH 707
G N SGP P P QMPPQ PP +
Sbjct: 947 PLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQ 1006
Query: 708 PAL---SQSPMPQERGFMAGTQRNPQMAQYGPQQTGP-------SMSPHPSPGGQMHAGI 757
P L Q P P + Q+ QM Q P S + HP P G ++
Sbjct: 1007 PQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHP-PRGPLNPD- 1064
Query: 758 SSFQQSNSSGTYGPQMSQYGPQ-------------------GNYSRPPAYSGVPSASYSG 798
S SG+ +S GP G+ SR Y P S
Sbjct: 1065 SQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSS 1124
Query: 799 PGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQ-QGG 857
P M S + PS P G MPS + P N MT PG S
Sbjct: 1125 PLAEMA-SLPEASGSEAPSVPGGP---NNMPS----HVVLPQNQLMMTGPKPGPSPLSAT 1176
Query: 858 PGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSS 917
G P P VN AA + SR ++ AS PY P ++
Sbjct: 1177 QGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRP-------KTPNRASPRPY-YPQTPNNR 1228
Query: 918 LMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQP------ES 971
+T+ S++P +N+S A + P + +PLP P+P +
Sbjct: 1229 PPSTEPSEISLSPERLNASIAG------LFPPQINIPLP----------PRPNLNRGFDQ 1272
Query: 972 KSKDSYSSQGISQPPT-----PGNLPVPSPMSPSSASISSFHGDESDS----ISSPGWPK 1022
+ + + + I Q P+ P N P S ++S G +S+S +SP +
Sbjct: 1273 QGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNS--GKQSNSGATKRASPSNSR 1330
Query: 1023 TPSSPKSSSSTT--TGEKITKVYELGNEPERKLWVDRYLTFMEE---RGSPVSSLPAVGK 1077
SSP SS TT G + +K +L + + + + +P+++ P G
Sbjct: 1331 R-SSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGS 1389
Query: 1078 KP----LDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQ-----YI 1128
P L+ V V +GG+ + NK +LNV S +S ++ +
Sbjct: 1390 FPNNSGLNPQNSTVSVAAVGGVVEDNKE--------SLNVPQDSDCQNSQSRKEQVNIEL 1441
Query: 1129 QYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEV 1188
+ + A E K+ E+ + D K P ++ S +++ T S ++
Sbjct: 1442 KAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAP 1501
Query: 1189 PGDLKPPTPASTPHGQMTP--MQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNA 1240
+KPP ++TP + G SV D+S S P + P++
Sbjct: 1502 NVTIKPPGLTDL---EVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHS 1552
Score = 72.8 bits (177), Expect = 4e-12
Identities = 224/1066 (21%), Positives = 338/1066 (31%), Gaps = 189/1066 (17%)
Query: 594 EDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHA 653
E L ++ Q L DL I + E ++ A++ + S + + A + A
Sbjct: 106 ERLRILAQSNNQQLRDLG--ILSVQIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEA 163
Query: 654 SPHLSSIPG---GPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPAL 710
++S PG +P+ V P G N S S ++P P ++ P+ P S+S + L
Sbjct: 164 GFPMASGPGIIRMNNPATVMIPPGGNVS-SSMMAPG--PNPELQPRTPRPASQSDAMDPL 220
Query: 711 SQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYG 770
Q++ +G+ P P M+P P Q QQ
Sbjct: 221 LSGLHIQQQSHPSGSLAPPHHPMQ-PVSVNRQMNPANFPQLQQQQQQQQQQQQQQQ---- 275
Query: 771 PQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPS 830
Q Q Q +RPP Q H Q QP G P P+
Sbjct: 276 QQQQQQQQQQLQARPP-----------------------QQHQQ--QQPQGIRPQFTAPT 310
Query: 831 AGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQ 890
P PG +Q + PP A ++ AN ++
Sbjct: 311 --------------QVPVPPGWNQLPSGALQPP---------PAQGSLGTMTANQGW-KK 346
Query: 891 GSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAAS---VGLADMMS 947
PG P Q + SL Q P + P S AS M +
Sbjct: 347 APLPG-----------PMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSN 395
Query: 948 PGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSAS-ISS 1006
PG+ P G P P + QP P SP S S SS
Sbjct: 396 PGQFTAPQMKSLQGGPSRVPTP------------LQQPHLTNKSPASSPSSFQQGSPASS 443
Query: 1007 FHGDESDSISSPGWPKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERG 1066
+++ P P+ P+ + + + GN P + + +
Sbjct: 444 PTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQ----QPPNQ 499
Query: 1067 SPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLK-K 1125
P S P +G P L + Q N N ++ + +S A L+
Sbjct: 500 GPQSLHPGLGGMPKRLPPGF-------SAGQANPNFMQGQVPSTTATTPGNSGAPQLQAN 552
Query: 1126 QYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSM 1185
Q +Q+ +G PP + P + PS + G Q G++ +
Sbjct: 553 QNVQHAGG------QGAGPPQNQMQV--SHGPPNMMQPSLMG---IHGNMNNQQAGTSGV 601
Query: 1186 AEV-------PGDLKPPTPASTPHGQMTPMQGG---RSSTISVHDPFSDVSDSSFPKRNS 1235
+V PP+ H Q+ P QG + T++ +P +S + +
Sbjct: 602 PQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMI-LSRAQLMPQGQ 660
Query: 1236 MTPNAPYQ------QGMSMPDVM----GRMPYEPNKDPFGGMRKVPGSSEPFMTQ----- 1280
M N P Q Q M+ P M G P+ G +V P + Q
Sbjct: 661 MMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQ 720
Query: 1281 --GQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQP 1338
G + Q+ N P A G Q G + GQ P QGP + P
Sbjct: 721 MQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQ---GNMVQFTGQMSGQMLPQQGPVNNSP 777
Query: 1339 PYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQY----SSQQQEMYNQY----- 1389
G + P HM +G PA D+ Q S QQ M +
Sbjct: 778 SQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQ 837
Query: 1390 -----GGSYSGPD---RRPIQGQYPYPYSRERMQGPGQIQTHGIP--PQMMGGPLQSSSS 1439
G +SG P G P Q PG + ++ LQS S
Sbjct: 838 GNSASGNHFSGHGMSFNAPFSGA-PNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDIS 896
Query: 1440 EG------PQQNMWAARNDMPYPYQNRQG-----------PGGPTQA--PPYPG---MNR 1477
G Q N A + P + ++ P G +A PP PG +N
Sbjct: 897 AGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINL 956
Query: 1478 TDDMMVPDQRINHESQWPSHVSQRQPYMSSSAS-MQPITRPPQPSYQTP-PSLPNHISRA 1535
+ + N +PS +++P MQ + PPQP Q P P LP +
Sbjct: 957 DNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQ--QQ 1014
Query: 1536 PSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQP 1581
P P S +S + + + + M+ +P SQ PP P
Sbjct: 1015 PPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGP 1060
Score = 70.1 bits (170), Expect = 2e-11
Identities = 251/1147 (21%), Positives = 367/1147 (31%), Gaps = 255/1147 (22%)
Query: 329 AASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAP 388
A+S S GS A Q Q G P N L S G P + P
Sbjct: 429 ASSPSSFQQGSPASS--PTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVP 486
Query: 389 P--------PPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSH 440
P PP PQS G GM G A+P + Q S
Sbjct: 487 PNFMVMQQQPPNQGPQSLHPGLG----------GMPKRLPPGFSAGQANPNFMQGQVPST 536
Query: 441 PAMSPGTPGPTM-----------GRSQGSPMDPMV-------MKRPQLYGMGSNPHSQPQ 482
A +PG G G+ G P + M M +P L G+ N ++Q
Sbjct: 537 TATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQA 596
Query: 483 QSSPYPGGSYG--PPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQ 540
+S P + PQ+ P P + GM QQ+ P GQ QQG
Sbjct: 597 GTSGVPQVNLSNMQGQPQQGP-------PSQLMGMH---QQIVPSQGQM----VQQQG-- 640
Query: 541 PYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQ 600
+ PQ P + +AQ +P P Q++ R PP ++
Sbjct: 641 ---TLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQ--RMTPPK----------QMLS 685
Query: 601 QERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSI 660
Q+ P + + + P G + + T+ + + P + I
Sbjct: 686 QQGPQMMAPHNQMMG--PQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQI 743
Query: 661 PGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERG 720
GP+P+ G+ V SG + P P + P Q G Q + P S M Q+ G
Sbjct: 744 MRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPH-MAQQHG 802
Query: 721 FMAGTQRN----PQM-----------------AQYGPQQTGPSMSPH----------PSP 749
A T N QM A G +G S H
Sbjct: 803 DPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPN 862
Query: 750 GGQMHAG------------------ISSFQQSNSSGTYGPQMSQYGPQGN---YSRPPAY 788
G QM G ++ Q S+G +G Q N +PP
Sbjct: 863 GNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRK 922
Query: 789 S-------GVPSASYSG-------PGPG-MGISANNQMHGQGPSQPCGAVPLGRMPSAGM 833
P +G P PG GI+ +N GP P + PS +
Sbjct: 923 KKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDN----SGPKLPEFSNRPPGYPSQPV 978
Query: 834 QNRPF----PGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSR 889
+ RP P M + P QQ P P + ++ Q + Q+ Q +
Sbjct: 979 EQRPLQQMPPQLMQHVAPPPQPPQQQ-------PQPQLPQQQQPPPPSQPQSQQQQQQQQ 1031
Query: 890 QGSFPGMNQSGLMASSSPYSQ-------PMNNSSSLMNTQAPPYSMAPAMVN-SSAASVG 941
Q M Q + P SQ P+N S M Q P MV+ ASV
Sbjct: 1032 QMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQS--GSVPVMVSLQGPASV- 1088
Query: 942 LADMMSPGESKLPL----PLKADGKE---EGTPQPESKS--------KDSYSSQGISQPP 986
SP + ++P+ PL ++ ++ + +PQ S S ++ S+ S P
Sbjct: 1089 ---PPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPG 1145
Query: 987 TPGNLPV-----------------PSPMS---------PSSASISSFHGDESDSISSP-- 1018
P N+P PSP+S P S+ S HG ++++P
Sbjct: 1146 GPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQ 1205
Query: 1019 -GWPKTP--SSPKSSSSTTTGEK--ITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLP 1073
PKTP +SP+ T + T+ E+ PER L F + P+ P
Sbjct: 1206 TSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPER-LNASIAGLFPPQINIPLPPRP 1264
Query: 1074 AVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFA 1133
+ + D L + G A N AT S +S K+
Sbjct: 1265 NL-NRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKR 1323
Query: 1134 FECKIERGEEPPPEVFST----GDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVP 1189
R P +T K PKL S N+ LQ + P+ N +
Sbjct: 1324 ASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQNVELPR----NVLVSPT 1379
Query: 1190 GDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNA--------- 1240
PP P S P+ Q S +V D +S ++S N+
Sbjct: 1380 PLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNI 1439
Query: 1241 -----PYQQ-GMSMPDVMGR---MPYEPNKDP---------FGGMRKVPGSSEPFMTQGQ 1282
P Q+ M +P+ + P +PNK P MR+ P S +
Sbjct: 1440 ELKAVPAQEVKMVVPEDQSKKDGQPSDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSG 1499
Query: 1283 MPNSSMQ 1289
PN +++
Sbjct: 1500 APNVTIK 1506
Score = 49.3 bits (116), Expect = 4e-05
Identities = 89/347 (25%), Positives = 120/347 (34%), Gaps = 40/347 (11%)
Query: 1289 QDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLY 1348
QD+ P GA +++ M G R + P P G S G P L
Sbjct: 145 QDVRMNGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQ 204
Query: 1349 PQQPNYKRHMDGM------YGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQ 1402
P+ P D M + H + Q N+ + P + Q
Sbjct: 205 PRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQ 264
Query: 1403 GQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQ--QNMWAARNDMPYPYQNR 1460
Q +++ Q Q Q Q+ P Q + PQ + + A +P P
Sbjct: 265 QQQQQQQQQQQQQQQQQQQ-----QQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWN 319
Query: 1461 QGPGGPTQAPPYPGMNRT-------DDMMVP---DQRINHES-----QWPSHVSQRQPYM 1505
Q P G Q PP G T +P Q++ Q PSH P+
Sbjct: 320 QLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFG 379
Query: 1506 SSSASMQPITRPPQ---PSYQTPP---SLPNHISRAPSPASFQRSLENRMSPSKSPFLPS 1559
S AS Q T PQ P T P SL SR P+P Q L N+ SP+ SP
Sbjct: 380 SQQAS-QAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQ-QPHLTNK-SPASSPSSFQ 436
Query: 1560 MKMQKVMPTV-PTSQVTGP-PPQPPPIRREITFPPGSVEASQPVLKQ 1604
PTV T Q GP PPQ P+ + P S P+++Q
Sbjct: 437 QGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSS-PGRNPMVQQ 482
Score = 38.9 bits (89), Expect = 0.057
Identities = 159/776 (20%), Positives = 254/776 (32%), Gaps = 132/776 (17%)
Query: 352 QHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQA 411
Q P+ P+ ++ P P+ G + + +P P S P ++ A+ A+G +
Sbjct: 1083 QGPASVPPSPDKQ-RMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAP 1141
Query: 412 AAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPT-MGRSQGS-PMDPMVMKRPQ 469
+ G P+ Q P PGP+ + +QG+ P P V P
Sbjct: 1142 SVPGGPNN---------MPSHVVLPQNQLMMTGP-KPGPSPLSATQGATPQQPPVNSLPS 1191
Query: 470 LYG----------MGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQG--------RTPGA 511
+G S P + P ++SP P Y P P P + R +
Sbjct: 1192 SHGHHFPNVAAPTQTSRPKT-PNRASPRP---YYPQTPNNRPPSTEPSEISLSPERLNAS 1247
Query: 512 MAGMQYPQQQMPPQYGQQGVSGYCQQGQQPY----YSQQPQPPHLPPQAQYLP------- 560
+AG+ PQ +P G+ QQG P Q P + P P
Sbjct: 1248 IAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDS 1307
Query: 561 ----------SQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHE--DLNLIQQERPSSLP 608
S + +R P +R P +PG+ N + L L Q + L
Sbjct: 1308 VVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTP-SPGRQNSKAPKLTLASQTNAALLQ 1366
Query: 609 DLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPS- 667
++ +LP VS + + S P S +P S + GG
Sbjct: 1367 NV-----ELPRNV------LVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDN 1415
Query: 668 ------PVGSPVGSNQSRSGPISPA--SIPGSQMPPQPPGSQSESSSHPALSQSPMP--- 716
P S ++QSR ++ ++P ++ P QS+ P+ + +P
Sbjct: 1416 KESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPS-DPNKLPSVE 1474
Query: 717 QERGFMAGTQRN--------------PQMAQYGPQQTGPSMSPHPSPGGQMHAGI----- 757
+ + ++ R P + P T ++P G +
Sbjct: 1475 ENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTL 1534
Query: 758 ----SSFQQSNS----------SGTYGPQMSQYGPQGNYSRPPAYSG-VPSASYSGPGPG 802
SS + SNS S P++S+ S PP S V S+S S P P
Sbjct: 1535 QDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSISTPLPP 1594
Query: 803 MGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGP 862
I+ + S A + SA M N S S G S
Sbjct: 1595 NQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGSKVMVSEGQSA----AQSN 1650
Query: 863 PMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQ 922
P +++++Q S S + P SGLM S P++ ++ +
Sbjct: 1651 ARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAVVGPLHIPQNIKFSS 1710
Query: 923 APPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGI 982
AP V +A S A + G PL L + P P S S
Sbjct: 1711 AP--------VPPNALSSSPAPNIQTGR---PLVLSSRATPVQLPSPPCTSSPVVPSHPP 1759
Query: 983 SQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSSPKSSSSTTTGEK 1038
Q N SP +SA ++ +S ++ SP +P S + S + K
Sbjct: 1760 VQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSSGNRRSPVSSSK 1815
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 102 bits (255), Expect = 3e-21
Identities = 214/962 (22%), Positives = 315/962 (32%), Gaps = 135/962 (14%)
Query: 87 GGAPQPGPDMEQPQHGGAKDSAAGGQADP-----PGPPLLSKPGDEDDAPPKMGEPAGGR 141
GG P P S GG A P P PP ++ P PK G PA
Sbjct: 975 GGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS------PK-GSPAATP 1027
Query: 142 YEHPGLGALGTQQPPVAVPGGG-GGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQ 200
+ G PP A P G PAA P PA+ P + GP G
Sbjct: 1028 FPK------GASTPPAATPPSPKGSPAATPLPKG--APTTPAATLPSPKGGPATPSLKGA 1079
Query: 201 QSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGG 260
+P P + P P+ + P + P + GG G
Sbjct: 1080 PTP---------------PAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKG 1124
Query: 261 GSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVL--SSPRQQGG 318
+ GG A AA GG G ++P G
Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1184
Query: 319 GMMMGPGGGGAASLSKAAAGSAAGGFQRFA--GQNQHPSGATPTLNQLLTSPSPMMRSYG 376
G+ P GA + A S GG + G P+ P+ L +PSP G
Sbjct: 1185 GLAT-PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK----G 1239
Query: 377 GSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAA--SPAWAA 434
++P +P P+ P + A AA G+ GA A P+
Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG 1299
Query: 435 AQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGP 494
S P +P P T +GSP P P + +P P + P
Sbjct: 1300 GPATSPPKGAPTPPAATPPSPKGSPGTP------------------PPKGAPTPP-AVTP 1340
Query: 495 PGPQRYPIGIQGRTPGAMAGMQYPQQQ---MPPQYGQQGVSGYCQQGQQPYYSQQ-PQPP 550
P P+ P + TP + G P + PP G P P P
Sbjct: 1341 PSPKGTPT-LPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK 1399
Query: 551 HLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDL 610
P +P ++ P +++EG T S+ L P P ++L + S+
Sbjct: 1400 GDPTSPAVIPLSPKKA--PATPVTREGAATPSKGDLTP--PAVTPVSLKKAPATSA---- 1451
Query: 611 SGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVG 670
P G AT SS+GD + PA +P SP P + SP
Sbjct: 1452 -------PKGGPAT----------PSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP---- 1490
Query: 671 SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAG---TQR 727
+ P +PA + +P P S E + P+ + P+ ++
Sbjct: 1491 --------KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATL 1542
Query: 728 NPQMAQYGPQQTGPSMSPHPS-PGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPP 786
P+ A P T PS P+ P + S ++++S P + P P
Sbjct: 1543 APKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIP 1602
Query: 787 AYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMT 846
PS + P + + + GP+ P P + P + +S+T
Sbjct: 1603 PAVTSPSPKEAPTPPAVTPPSPEK----GPATPAPKGTPTSPPVTPSSLKDSPTSPASVT 1658
Query: 847 PSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSS 906
Q G+ K A A +A +R+G Q+ +++S
Sbjct: 1659 CKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGP-----QTKKSSATS 1713
Query: 907 PYSQP----MNNSSSLMNTQAPPYSMAPAMVNSSAASVGL------ADMMSPGESKLPLP 956
P P N S ++T AP + P +SS + G ++P ESK P
Sbjct: 1714 PPICPDPSAKNGSKGPLSTVAPA-PLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTP 1772
Query: 957 LKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSIS 1016
L A E+ P+PES S + S +S P P PVP+ + P + S G +S S
Sbjct: 1773 LTAAAFEKVLPKPESASVSAAPSPPVSLPLAPS--PVPT-LPPKQQFLPSSPGLVLESPS 1829
Query: 1017 SP 1018
P
Sbjct: 1830 KP 1831
Score = 90.5 bits (223), Expect = 2e-17
Identities = 292/1421 (20%), Positives = 467/1421 (32%), Gaps = 185/1421 (13%)
Query: 384 SPSAPPP--PPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAW----AAAQQ 437
SPS PP PP + + +A ++ +D GA A+S A +
Sbjct: 736 SPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPS 795
Query: 438 RSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGP 497
++SP T P + P P+ G S+P S P ++S P S G
Sbjct: 796 PLGVSVSPQTKRPPTKKGSAGPDTPI--------GNLSSPVS-PVEASFLPENSLSFQGS 846
Query: 498 QRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPH-----L 552
+ P TP + G P P +GV+ ++ P P P
Sbjct: 847 KDSPATTHSPTPPSPKGAPTPSAVTP--LSPKGVTLPPKETPTPSVVNLPFPKEGPATPA 904
Query: 553 PPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSG 612
P QA L S + + + +G P AP P P P +
Sbjct: 905 PKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP------AATPPSPKGGP-ATP 957
Query: 613 SIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSP 672
S PT AT S + S +G + PA +P SP P S G P+P V P
Sbjct: 958 SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP 1017
Query: 673 VGSNQSRSGPISP-ASIPGSQMPPQPPGSQSES---SSHPALSQSPMPQERGFMAGTQRN 728
+ P AS P + PP P GS + + P + +P +G
Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG-------G 1070
Query: 729 PQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAY 788
P T P+ +P PSP G S P + P+G + PP +
Sbjct: 1071 PATPSLKGAPTPPAATP-PSPKG------GPATPSPKGAPMPPAATPPSPKGGLATPP-H 1122
Query: 789 SGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPS 848
G P+ + P G A G P+ P P P G+ P G + TP+
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKG-APTTPAATPP---SPKGGLATPPPKG--APTTPA 1176
Query: 849 SPGMSQQGG-----PGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMA 903
+ S +GG P P P + + A + A + + P + GL A
Sbjct: 1177 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT--PSPKGAPTTPAATPPSPKGGL-A 1233
Query: 904 SSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKE 963
+ SP P +++ + + P + P + A+ +P K L A
Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAA-------TPPSLKGGL---ATPPH 1283
Query: 964 EGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPM----SPSSASISSFHGDESDSISSPG 1019
+G P P + PP+P P SP +P +A+ S G SPG
Sbjct: 1284 KGAPNP-----------AVVTPPSPKGGPATSPPKGAPTPPAATPPSPKG-------SPG 1325
Query: 1020 WPKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKP 1079
P +P + T K T T +G P + G P
Sbjct: 1326 TPPPKGAPTPPAVTPPSPKGTPTLPA--------------TTPSSKGGPTTPSSKEGPTP 1371
Query: 1080 LDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAA----SSLKKQYIQYLFAFE 1135
GG A + K R A G +S A S K
Sbjct: 1372 PA-----ATPSHKGGPAMTPPSPK-RGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGA 1425
Query: 1136 CKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEV--PGDLK 1193
+G+ PP V P +PA S GP TP S G ++ V P +
Sbjct: 1426 ATPSKGDLTPPAV--------TPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE 1477
Query: 1194 PPTP------ASTPHGQMTPMQGGRSSTISVHDPFS--DVSDSSFPKRNSMTPNAPYQQG 1245
PP P +S TP G + T+ P S +V + +R+ + P A
Sbjct: 1478 PPAPKQVATSSSPKKAPATPAPMG-APTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSK 1536
Query: 1246 MSMPDVMGRMPYEPNKDPFGGMRKVP-------GSSEPFMTQGQMPNSSMQDMYNQSPSG 1298
+ + + P +K P + P + P + Y +PS
Sbjct: 1537 KTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSP 1596
Query: 1299 AMSNLGMGQRQQFPYGA-SYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRH 1357
+ P A + P ++ P P G P P P
Sbjct: 1597 KELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPAS 1656
Query: 1358 MDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGP 1417
+ G + + + + +E+ P+ PI + +GP
Sbjct: 1657 VTCKMGATVPQASKGLPAKKGPTALKEVL-----VAPAPESTPI-------ITAPTRKGP 1704
Query: 1418 GQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAA-----RNDMPYPYQNR---QGPGGPTQA 1469
++ P + P + S+GP + A + D + + P GP A
Sbjct: 1705 QTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPL-A 1763
Query: 1470 PPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLP 1529
PP T +++ + + S + P +S + P+ P P Q PS P
Sbjct: 1764 PP-ESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLP-PKQQFLPSSP 1821
Query: 1530 NHISRAPSPASFQRSLENRMSP--SKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRRE 1587
+ +PS + E+ + P P + Q V+ +PT + G P P ++
Sbjct: 1822 GLVLESPS-KPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQP 1880
Query: 1588 IT---FPPGSVEASQPVLKQRRKITSKDIVTPEAW----------RVMMSLKSGLLAEST 1634
+T G+ S + + + S T +A V + +S ++
Sbjct: 1881 VTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKAR 1940
Query: 1635 WALDTINILLYDDSTVATFNLSQLSGFLELLVEYFRKCLIDIFGILMEYEVGDPSQKALD 1694
A+ + + T T S+ F+ + ++ D + + E ++ D SQ+A
Sbjct: 1941 KAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQA-Q 1999
Query: 1695 HNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSE 1735
AA K Q A + +E + ++ E+EE +E E
Sbjct: 2000 LAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVE 2040
Score = 79.3 bits (194), Expect = 4e-14
Identities = 149/689 (21%), Positives = 234/689 (33%), Gaps = 76/689 (11%)
Query: 380 PEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRS 439
P + PP P P A + G + + PA A +Q
Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQA- 908
Query: 440 HPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQR 499
PA+S + P R+ +P + P G + P + P P P G P P+
Sbjct: 909 -PALSMTSSSPKKARATPAPKG--IPASPSPKGAPTPPAATP----PSPKGGPATPSPKW 961
Query: 500 YPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHL-PPQAQY 558
P P G P + P P P PP + PP +
Sbjct: 962 APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKG 1021
Query: 559 LPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLP 618
P+ + P+ G + P P P P++ P G+ P
Sbjct: 1022 SPAATPF---PK--------GASTPPAATPPSPKGS---------PAATPLPKGA----P 1057
Query: 619 TGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGP------SPSPVGSP 672
T ATL S + S +G + PA +P SP P S G P PSP G
Sbjct: 1058 TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGG- 1116
Query: 673 VGSNQSRSGPISPASIP----GSQMPPQPPGSQSESSSHP-----ALSQSPMPQERGFMA 723
+ + + P +PA+ P G P P G+ + ++ P L+ P A
Sbjct: 1117 LATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1176
Query: 724 GTQRNPQMAQYGPQQTGPSMSP---HPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQG 780
T +P+ P G +P PSP G G+++ + T P + P+G
Sbjct: 1177 ATPPSPKGGLATPSPKGAPTTPAATPPSPKG----GLATPSPKGAPTT--PAATPPSPKG 1230
Query: 781 NYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPG 840
+ P+ G P+ + P G A G P+ P P G+ P G
Sbjct: 1231 GLA-TPSPKGAPTTPAATPPSPKGGPATPPPKG-APTPPAATPP---SLKGGLATPPHKG 1285
Query: 841 --NMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQ 898
N + +TP SP P G P P + + + P
Sbjct: 1286 APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345
Query: 899 SGLMASSSPYSQ-----PMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKL 953
+ + +++P S+ P + P + PAM S G A G+
Sbjct: 1346 TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKR-GPAIPSPKGDPTS 1404
Query: 954 PLPLKADGKEEGTPQPESKSKDSYSSQGISQPP--TPGNL-PVPSPMSPSSA-SISSFHG 1009
P + K + P ++ + S+G PP TP +L P+ +P + S G
Sbjct: 1405 PAVIPLSPK-KAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463
Query: 1010 DESDSISSPGWPKTPSSPKSSSSTTTGEK 1038
D + +P PK P +PK +++++ +K
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKK 1492
Score = 77.8 bits (190), Expect = 1e-13
Identities = 224/1032 (21%), Positives = 317/1032 (30%), Gaps = 243/1032 (23%)
Query: 604 PSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQS------PFSPHASPHL 657
P D +G GT ++A T S +++P + P P AS
Sbjct: 649 PLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTAS--- 705
Query: 658 SSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQ--PPGSQ-----SESSSHPAL 710
+ P PSP +P+ + P P S+P +PP PPG++ S +S+ +
Sbjct: 706 ENCPVAPSPQNTCAPLATLVL--APEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPV 763
Query: 711 SQSPM--PQERGFMAGTQRNPQMAQY---GPQQTGPSMSPHPSPGGQMHAGISSFQQSNS 765
+ SP P E + T + Y P G S+SP +
Sbjct: 764 ASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTK------------RPPTK 811
Query: 766 SGTYGPQMSQYGPQGNYSRPPA---YSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGA 822
G+ GP P GN S P + S +P S S G + H P P GA
Sbjct: 812 KGSAGPDT----PIGNLSSPVSPVEASFLPENSLSFQGSKDSPATT---HSPTPPSPKGA 864
Query: 823 VPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAA 882
PSA P + +P + P GP P A + A A+ +
Sbjct: 865 PT----PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP-----APKQAPALSMTS 915
Query: 883 ANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGL 942
++ ++R P G+ AS SP P PP + P+ A
Sbjct: 916 SSPKKARATPAP----KGIPASPSPKGAP-----------TPPAATPPSPKGGPAT---- 956
Query: 943 ADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSA 1002
P P A TP S +G P+P P P +P S
Sbjct: 957 -----------PSPKWAPTPPAATPP---------SPKGGPATPSPKGAPTPPAATPPSP 996
Query: 1003 SISSFHGDESDSISSPGWPKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFM 1062
+ + P TP SPK S + T K P K
Sbjct: 997 KGGPATPSPKGAPTPPA--VTPPSPKGSPAATPFPKGASTPPAATPPSPK---------- 1044
Query: 1063 EERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASS 1122
GSP ++ G A L A S
Sbjct: 1045 ---GSPAATPLPKGAPTTP--------------------------AATLPSPKGGPATPS 1075
Query: 1123 LKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGS 1182
LK G PP T PK P +P+ G+ P +
Sbjct: 1076 LK----------------GAPTPPAA-----TPPSPKGGPATPSPKGAPMPPAATPPSPK 1114
Query: 1183 NSMAEVPGDLKPPTPASTP----HGQMTPMQGGRSSTISVHDP-----FSDVSDSSFPKR 1233
+A P P TPA+TP G TP G +T + P + P
Sbjct: 1115 GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT 1174
Query: 1234 NSMTPNAPYQQGMSMPDVMG--RMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDM 1291
+ TP +P + G++ P G P P GG+ P T P S +
Sbjct: 1175 PAATPPSP-KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP-TTPAATPPSPKGGL 1232
Query: 1292 YNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQ 1351
SP GA + P +G P+ PP G P
Sbjct: 1233 ATPSPKGAPTT--------------------PAATPPSPKGGPATPPPKGAPTPPA-ATP 1271
Query: 1352 PNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQ------- 1404
P+ K G+ PP K S + + G+ + P P +
Sbjct: 1272 PSLK---GGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPP 1328
Query: 1405 ---YPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQ 1461
P P + G P GGP SS EGP P
Sbjct: 1329 PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP-----------PAATPS 1377
Query: 1462 GPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITR----P 1517
GGP PP P +P + + S P+ + P A P+TR
Sbjct: 1378 HKGGPAMTPPSPKRGPA----IPSPKGDPTS--PAVI----PLSPKKAPATPVTREGAAT 1427
Query: 1518 PQPSYQTPPSL-PNHISRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTG 1576
P TPP++ P + +AP+ + +P P PS K PT+P VT
Sbjct: 1428 PSKGDLTPPAVTPVSLKKAPATS----------APKGGPATPSSKGD---PTLPA--VTP 1472
Query: 1577 PPPQPPPIRREI 1588
P P+ PP +++
Sbjct: 1473 PSPKEPPAPKQV 1484
Score = 48.1 bits (113), Expect = 9e-05
Identities = 210/1042 (20%), Positives = 317/1042 (30%), Gaps = 162/1042 (15%)
Query: 585 PLAPGKPNHEDLN------LIQQERPSSLPDLSGSIDDLP---------TGTEATLSSAV 629
P++P P+ EDL L++ L + S++ P T + T+ V
Sbjct: 504 PVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLV 563
Query: 630 SAS--GSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPAS 687
A+ S S Q S+P + P SP A+ S+ P P+G P S S G S AS
Sbjct: 564 QAAPKNSPSFQSTSSSP-EIPLSPEATLAKKSLG---EPLPIGKPASSMTSPLGVNSSAS 619
Query: 688 IPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHP 747
+ + P S+ P L S + P +A + + P
Sbjct: 620 VIKTDSYAGP------DSAGPLLKSSLI------------TPTVAAFPLESADP------ 655
Query: 748 SPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISA 807
AG++ +S TY S + +G S P V + + P + ++
Sbjct: 656 -------AGVAPTTAKGTS-TYTTTASPF-LEGTVSLAPKNHPVKEGTLTTL-PLVPTAS 705
Query: 808 NNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTV 867
N P C PL + A + P + PG + G + V
Sbjct: 706 ENCPVAPSPQNTCA--PLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPV 763
Query: 868 NRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYS 927
+E A+A ++ ++ + S L S SP T+ PP
Sbjct: 764 ASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSP------------QTKRPPTK 811
Query: 928 MAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPT 987
S+ + ++ SP P++A E + + SKDS ++ PP+
Sbjct: 812 KG-----SAGPDTPIGNLSSPVS-----PVEASFLPENSLSFQG-SKDSPATTHSPTPPS 860
Query: 988 PGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSSPKSSSSTTTGEKITKVYELGN 1047
P P PS ++P S + E+ + S P PK +T ++ + +
Sbjct: 861 PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLP----FPKEGPATPAPKQAPALSMTSS 916
Query: 1048 EPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWREL 1107
P++ +G P S P P GG A + KW
Sbjct: 917 SPKKARATPA------PKGIPASPSPKGAPTP----PAATPPSPKGGPA--TPSPKWAPT 964
Query: 1108 ATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPAN 1167
+ ++ + A +G P S P + PPSP
Sbjct: 965 PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP---SPKGAPTPPAVTPPSPKG 1021
Query: 1168 SGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSD 1227
S P +T A P PP+P +P P + ++ P +
Sbjct: 1022 S--------PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT 1073
Query: 1228 SSF---PKRNSMTPNAPYQQGMSMPDVMGRM--PYEPNKDPFGGMRKVPGSSEPFMTQGQ 1282
S P + TP +P + G + P G P P GG+ P P T
Sbjct: 1074 PSLKGAPTPPAATPPSP-KGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP-TTPAA 1131
Query: 1283 MPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGG 1342
P S + P GA + P G G P PP G P
Sbjct: 1132 TPPSPKGGLATPPPKGAPTT--PAATPPSPKG----------GLATP---PPKGAPT--- 1173
Query: 1343 HQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQ 1402
P P P G+ P K S + G+ + P P
Sbjct: 1174 -TPAATPPSPK-----GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP-- 1225
Query: 1403 GQYPYPYSRERMQGPGQIQTH--GIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNR 1460
P P P T PP GGP P P
Sbjct: 1226 ---PSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTP-----------PAATP 1271
Query: 1461 QGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQP 1520
G PP+ G + P + + P S P T PP+
Sbjct: 1272 PSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKG 1331
Query: 1521 SYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQ 1580
+ TPP++ PSP S P PS K P S GP
Sbjct: 1332 A-PTPPAVT-----PPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385
Query: 1581 PPPIRREITFPPGSVEASQPVL 1602
PP +R P + + P +
Sbjct: 1386 PPSPKRGPAIPSPKGDPTSPAV 1407
Score = 45.1 bits (105), Expect = 8e-04
Identities = 235/1111 (21%), Positives = 342/1111 (30%), Gaps = 183/1111 (16%)
Query: 579 GTRSQPPLAPGKPNHEDLNLIQ-QERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSS 637
GT S P + P H + Q +SLP + PT T A S V + +S
Sbjct: 201 GTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTT------PTTTLAIASPQVKDTTISSV 254
Query: 638 QGDQSNPA----QSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQM 693
NP + P SP A+ LS+ PV V S+Q +GP +P P S
Sbjct: 255 LISPQNPGSLSLKGPVSPPAALSLST-----QSLPV---VTSSQKTAGPNTPPDFPISLG 306
Query: 694 PPQPPGSQSESSSHPALSQ---SPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPG 750
P QS S L Q S + + A Y Q++ + P PS
Sbjct: 307 SHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRS--VIPPLPSRN 364
Query: 751 GQMHAGISSFQQSNSSGTYGPQMSQY---GPQGNYSRPPAYSGVPSASY---SGPGPGMG 804
+ A +++F S GP P G+ + ++S P+ S S P
Sbjct: 365 EVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYH 424
Query: 805 ISANNQMH----GQGP---SQPC--GAVPLGRMPSAGMQNRPFP-GNMSSMTPSSPGMSQ 854
QM G P + PC A P A + P G +S++ P+SP
Sbjct: 425 YPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALV 484
Query: 855 QGGPG---------------MGPPMPTV-NRKAQEAAAAVMQAAANSAQSRQGSFPGMN- 897
+ PP+P + K ++ V Q+ S G
Sbjct: 485 MAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPF 544
Query: 898 ---QSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKL- 953
Q+GL P P+ QA P + SS+ + L+ + + L
Sbjct: 545 SPAQAGLTTKKDPTVLPL--------VQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLG 596
Query: 954 -PLPLKADGKEEGTPQPESKSK-----DSYSSQGISQP--------PTPGNLPV----PS 995
PLP+ +P + S DSY+ + P PT P+ P+
Sbjct: 597 EPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPA 656
Query: 996 PMSPSSASISSFHGDESDSISSPGWPKTPSS-PKSSSSTTTGEKITKVYE---LGNEPER 1051
++P++A +S + + P + P + TT + E + P+
Sbjct: 657 GVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQN 716
Query: 1052 KLWVDRYLTFMEE--RGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELAT 1109
L E + P SLP G P K++ G++ +
Sbjct: 717 TCAPLATLVLAPEIPKSVPSPSLPPAGTPP--------GTKKVDGISHTSALAPVASSPK 768
Query: 1110 NLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANS- 1168
S ++A++ K + YL + P P S K+P + S
Sbjct: 769 ECPTEDSGASATASSKGTLTYL---------ADSPSPLGVSVSPQTKRPPTKKGSAGPDT 819
Query: 1169 --GSLQGPQTPQSTG---SNSMA-----EVPGDLKPPTPASTPHGQMTPMQGGRSSTISV 1218
G+L P +P NS++ + P PTP S P G TP S V
Sbjct: 820 PIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS-PKGAPTPSAVTPLSPKGV 878
Query: 1219 -----HDPFSDVSDSSFPKRNSMTP---NAPYQQGMSMPDVMGRMPYEPNKDPFG----G 1266
P V + FPK TP AP S R P P G
Sbjct: 879 TLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKG 938
Query: 1267 MRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQ 1326
P ++ P G P + P+ + G P GA P
Sbjct: 939 APTPPAATPPSPKGG--PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP--- 993
Query: 1327 QYPGQGPPSGQPPYGGHQPGLYPQQPN----YKRHMDGMYGPPAKRHEGDMYNMQYSSQQ 1382
P GP + P P + P P G PPA + +
Sbjct: 994 PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP 1053
Query: 1383 QEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGP 1442
+ + P P P + P PP GGP S P
Sbjct: 1054 KGAPTTPAATLPSPKGGPAT-----PSLKGAPTPPA-----ATPPSPKGGPATPSPKGAP 1103
Query: 1443 QQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQ 1502
MP P P G PP+ G T P + + P
Sbjct: 1104 ----------MP-PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPP------- 1145
Query: 1503 PYMSSSASMQPITRPPQP--SYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSM 1560
A P PP P TPP + A +P S + L SP +P P+
Sbjct: 1146 ----KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT-PSPKGAPTTPA- 1199
Query: 1561 KMQKVMPTVPTSQVTGPPPQPPPIRREITFP 1591
P P + P P+ P T P
Sbjct: 1200 ----ATPPSPKGGLATPSPKGAPTTPAATPP 1226
Score = 38.5 bits (88), Expect = 0.075
Identities = 67/286 (23%), Positives = 109/286 (38%), Gaps = 50/286 (17%)
Query: 773 MSQYGPQGNYSRPPAYSGVP------SASYSGPGPGMGISANNQMHGQGPSQPCG-AVPL 825
+ Q GP + PP S P +A+ + P P A+ + P G A+PL
Sbjct: 38 LGQPGP----TLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPL 93
Query: 826 GRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANS 885
G P A F N+ P SP P + P T+ +A + A A
Sbjct: 94 GTAPEAPT----FLPNLIG-PPISPAALALASPMIAP---TLKGTPSSSAPLALVALAPH 145
Query: 886 AQSRQGSFP----------GMNQSG-LMASSSPY--SQPMNNSSSLMNTQAP--PYSMAP 930
+ + +FP + +SG ++ S+P S+P N + + + P + +P
Sbjct: 146 SVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSP 205
Query: 931 AMVNSSAASVGLADMMS--PGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTP 988
+ S+ + M S G + LP +PQ KD+ S + P P
Sbjct: 206 PCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQV----KDTTISSVLISPQNP 261
Query: 989 GNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSSPKSSSSTT 1034
G+L + P+SP +A S+S+ P SS K++ T
Sbjct: 262 GSLSLKGPVSPPAAL----------SLSTQSLPVVTSSQKTAGPNT 297
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 101 bits (251), Expect = 9e-21
Identities = 251/1038 (24%), Positives = 322/1038 (31%), Gaps = 231/1038 (22%)
Query: 82 LGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGR 141
L G GGA GP E G + G PPG KPG++ GEP GR
Sbjct: 226 LQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPG-----KPGED-------GEP--GR 271
Query: 142 YEHPG-LGALGTQQPPVAVPGGGGGPAA--VPEFNNYYGS----------AAPASGGPGG 188
+PG +G G+ PG G P A +P + G AP S G G
Sbjct: 272 NGNPGEVGFAGS-------PGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAG 324
Query: 189 RAGPC--------------FDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPN 234
GP + G Q +PG H G PG M PL G P
Sbjct: 325 PTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAH----GMPGKPGPMGPL-----GIPG 375
Query: 235 SQCNHYPGYSRPGAGGGGG--GGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAA 292
S + +PG PG G G G G G G G G G G+ A A
Sbjct: 376 S--SGFPG--NPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAK 431
Query: 293 GGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQ 352
G G G G G SP QG GP G + GF+ AG
Sbjct: 432 GPTGSPGTSGPPGSAGPPGSPGPQGS---TGPQG-----IRGQPGDPGVPGFKGEAGPKG 483
Query: 353 HPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAA 412
P + P G P + PP P G++ A
Sbjct: 484 EPG------PHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPV--------------GERGA 523
Query: 413 AGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYG 472
G + G + P AQ P S G G SQG P P P G
Sbjct: 524 PG-----NRGFPGSDGLPGPKGAQGERGPVGSSGPKG-----SQGDPGRPGEPGLPGARG 573
Query: 473 MGSNPHSQPQQ------SSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQM--PP 524
+ NP Q + +P G GPPG IGI+G+ PG+M G+ P+ P
Sbjct: 574 LTGNPGVQGPEGKLGPLGAPGEDGRPGPPG----SIGIRGQ-PGSM-GLPGPKGSSGDPG 627
Query: 525 QYGQQGVSGYCQQGQQPYYSQQ--PQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRS 582
+ G+ G +G Q P + P P PP + + P +G
Sbjct: 628 KPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGL----AGERGEQGPPGPTGFQGLPGPP 683
Query: 583 QPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQS 642
PP GKP + +P G++ L E G T G++
Sbjct: 684 GPPGEGGKPGDQ-----------GVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKG 732
Query: 643 NP-AQSPFSPHASPHLSSIPG--GP--------------SPSPVGSPVG----SNQSRSG 681
P P SP S PG GP +P P G G + +G
Sbjct: 733 MAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAG 792
Query: 682 PISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMA--GTQRNP-QMAQYGPQQ 738
+PG PP P G E P RG + G++ NP + GP
Sbjct: 793 NDGARGLPGPLGPPGPAGPTGEKGE---------PGPRGLVGPPGSRGNPGSRGENGPTG 843
Query: 739 ----TGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQ--MSQYGPQGNYSRPPAYSG-- 790
GP P PG + G Q +G+ GPQ GP G P G
Sbjct: 844 AVGFAGP-QGPDGQPGVKGEPGEPG--QKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRG 900
Query: 791 --VPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRP-FPGNMSSMTP 847
P + PG + GP+ P G G+ G++ P G + P
Sbjct: 901 TQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEP--GKEGPPGLRGDPGSHGRVGDRGP 958
Query: 848 SSP--GMSQQGGPGM-------GPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGM-N 897
+ P G +G PG GPP P A + Q PG
Sbjct: 959 AGPPGGPGDKGDPGEDGQPGPDGPPGP----------------AGTTGQRGIVGMPGQRG 1002
Query: 898 QSGLMASSSPYSQPMN-NSSSLMNTQAPPYSMAPAMVNSSAASVG--------------- 941
+ G+ P P + + PP + P N G
Sbjct: 1003 ERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDG 1062
Query: 942 ----LADMMSPGESKLPLPLKADGK--EEGTPQPESKSKDSYSSQGISQPPTPGNLPVPS 995
D PG + LP A G G P + D S I P G +P
Sbjct: 1063 AVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPG 1122
Query: 996 PMSPSSASISSFHGDESD 1013
P P HGD D
Sbjct: 1123 PQGPRGD--KGDHGDRGD 1138
Score = 95.5 bits (236), Expect = 5e-19
Identities = 202/783 (25%), Positives = 245/783 (31%), Gaps = 163/783 (20%)
Query: 75 PISNNNSLGGAG--GGAPQPGPDMEQPQHGGAKDSAA-GGQADP--PGPP-------LLS 122
P+ + G G G PGP Q + G S G Q DP PG P L
Sbjct: 517 PVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTG 576
Query: 123 KPG---DEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPG--GGGGPAAVPEFNNYYG 177
PG E P GR PG + Q + +PG G G P G
Sbjct: 577 NPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKP------G 630
Query: 178 SAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQC 237
A A G PG R P D G P + G PG +G P
Sbjct: 631 EAGNA-GVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGP-----TGFQGLPGP-- 682
Query: 238 NHYPGYSRPGAGGGGGGGG-----------GGGGGSGGGGGGGGAGAGGAGAGAVAAAAA 286
PG PG GG G G G G G G G G G A
Sbjct: 683 ---PG--PPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGH 737
Query: 287 AAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAG-GFQ 345
G G G G + G+ P ++G GP G K A G+A G +
Sbjct: 738 GPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGAR 797
Query: 346 RFAGQNQHPSGATPTLNQLLTSPS-----PMMRSYGGSYPEYSSPSAPP-PPPSQPQSQA 399
G P A PT + P P R GS E A P P Q
Sbjct: 798 GLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQP 857
Query: 400 AAAGAAAG-GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR-SQG 457
G GQ+ AG G Q A SP P G PG GR +QG
Sbjct: 858 GVKGEPGEPGQKGDAG-----SPGPQGLAGSPG---------PHGPNGVPGLKGGRGTQG 903
Query: 458 SPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGP-----QRYPIGIQGRTPGAM 512
P G P S + P P G+ GP GP + P G++G PG+
Sbjct: 904 PP------------GATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRG-DPGSH 950
Query: 513 AGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQY--LPSQSQQRYQP- 569
+ PP G G G + QP P P Q +P Q +R P
Sbjct: 951 GRVGDRGPAGPP--GGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPG 1008
Query: 570 -------QQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTE 622
+ G PP G P P P G P G +
Sbjct: 1009 LPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNG--------PVGEPGPEG-----PAGND 1055
Query: 623 ATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQ----S 678
T G+ +GD+ +P P P PG +P PVG+P + Q
Sbjct: 1056 GT----PGRDGAVGERGDRGDPG-----PAGLPGSQGAPG--TPGPVGAPGDAGQRGDPG 1104
Query: 679 RSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQ 738
GPI P G + P P G + + H RGF G Q P GP
Sbjct: 1105 SRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGF-TGLQGLP-----GP-- 1156
Query: 739 TGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSG 798
P P G + S+G GP +GP+G PP G PS
Sbjct: 1157 --------PGPNG----------EQGSAGIPGP----FGPRG----PPGPVG-PSGKEGN 1189
Query: 799 PGP 801
PGP
Sbjct: 1190 PGP 1192
Score = 85.9 bits (211), Expect = 4e-16
Identities = 166/667 (24%), Positives = 209/667 (31%), Gaps = 141/667 (21%)
Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS-KPGDED-DAPPKMGEPAGGR 141
G G PG E+ + G + G PPGPP KPGD+ P P G R
Sbjct: 651 GPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPR 710
Query: 142 YEH--------PGLGALGTQQPPVAV-----PGGGGGPAAVPEFNNYYG-SAAPASGGPG 187
E PG+ L ++ P G GP+ P G P G
Sbjct: 711 GERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIA 770
Query: 188 GRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPL----QNSHEGYPNSQCNHYPGY 243
G GP D+ G + G + + A G PG + P +G P + G
Sbjct: 771 GTPGPKGDRGGIGEKGAEGT--AGNDGARGLPGPLGPPGPAGPTGEKGEPGPR-----GL 823
Query: 244 SRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGS 303
P G G G G +G G G G G AG G G GS
Sbjct: 824 VGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGS 883
Query: 304 SAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPS-----GAT 358
+G P +GG GP G A GF AG+ P G
Sbjct: 884 PGPHGPNGVPGLKGGRGTQGPPG--------------ATGFPGSAGRVGPPGPAGAPGPA 929
Query: 359 PTLNQLLTSPSPMMRSYGGSYPEYSS--PSAPPPPPS---------QPQSQAAAAGAAAG 407
L + P +R GS+ P+ PP P QP A
Sbjct: 930 GPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTT 989
Query: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPM---- 463
GQ+ GM G + P PA +PG GPT P P+
Sbjct: 990 GQRGIVGMP-----GQRGERGMPGLPG------PAGTPGKVGPTGATGDKGPPGPVGPPG 1038
Query: 464 ---VMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGR--TPGAMAGMQYP 518
+ P G N + + + G G PGP P G QG TPG +
Sbjct: 1039 SNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLP-GSQGAPGTPGPVGA---- 1093
Query: 519 QQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEG- 577
P GQ+G G S+ P P + LP PQ +G
Sbjct: 1094 ----PGDAGQRGDPG----------SRGPIGPPGRAGKRGLPG-------PQGPRGDKGD 1132
Query: 578 YGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSS 637
+G R G+ H +Q LP G P G + GS
Sbjct: 1133 HGDRGDR----GQKGHRGFTGLQ-----GLPGPPG-----PNGEQ----------GSAGI 1168
Query: 638 QGDQSNPAQSPFSPHASPHL---SSIPGGPSP-SPVGSP-VGSNQSRSGPISPASIPGSQ 692
G PF P P S G P P P+G P V + +GP P PG
Sbjct: 1169 PG--------PFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPP 1220
Query: 693 MPPQPPG 699
PP PPG
Sbjct: 1221 GPPGPPG 1227
Score = 85.1 bits (209), Expect = 7e-16
Identities = 249/1035 (24%), Positives = 327/1035 (31%), Gaps = 198/1035 (19%)
Query: 113 ADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVP-----GGGGGPA 167
ADP PP + P + GG + G G G + P VP G GPA
Sbjct: 83 ADPVTPP--------GECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPA 134
Query: 168 AVPEFNNYYGSAAP-ASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAA-----GAPGS 221
P GS P GP GR GP Q G PG+ A G G
Sbjct: 135 GPP------GSQGPRGERGPKGRPGPRGPQ-GIDGEPGVPGQPGAPGPPGHPSHPGPDGL 187
Query: 222 MDPLQNSHEGYPN-----SQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGA 276
P G SQ PG P G G G GG+G G G G G
Sbjct: 188 SRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGP 247
Query: 277 GAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAA 336
+ G G G G+ G SP +G PG G L
Sbjct: 248 MGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARG-----FPGAPGLPGLKGHR 302
Query: 337 AGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQ 396
G + G A PT PM P P P
Sbjct: 303 GHKGLEGPKGEVGAPGSKGEAGPT--------GPM------------GAMGPLGPRGMPG 342
Query: 397 SQAAAAGAAAGGQQAAAGM----GLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTM 452
+ A GQ+ A GM G +G ++ P + + P + G GP
Sbjct: 343 ERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQG 402
Query: 453 GRSQGSPMDPMVMK-RPQLYGMGSNPHSQPQQSSP---YPGGSYGP---PGPQ--RYPIG 503
R + P P+ P G P ++ SP P GS GP PGPQ P G
Sbjct: 403 QRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQG 462
Query: 504 IQGR--TPG--AMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQP----PHLP-- 553
I+G+ PG G P+ + P +G QG G G++ + P P P
Sbjct: 463 IRGQPGDPGVPGFKGEAGPKGE-PGPHGIQGPIG--PPGEEGKRGPRGDPGTVGPPGPVG 519
Query: 554 ----------PQAQYLPSQSQQRYQPQQDMSQEGYGTRSQP--PLAPGKPNHEDL--NLI 599
P + LP + + S G++ P P PG P L N
Sbjct: 520 ERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPG 579
Query: 600 QQERPSSLPDLSGSIDDLPTGTEATLS-----SAVSASGSTSSQGDQSNPAQSPFSPHAS 654
Q L L +D G ++ ++ G S GD P ++
Sbjct: 580 VQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEA--GNAGV 637
Query: 655 PHLSSIPG-----GPSPSPVGSP-VGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHP 708
P PG GPS PVG P + + GP P G PP PPG
Sbjct: 638 PGQRGAPGKDGEVGPS-GPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGE-------- 688
Query: 709 ALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGP--SMSPHPSPGGQMHAGISSFQ-QSNS 765
G + Q P GP +PG + GI+ +
Sbjct: 689 ---------------GGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGM 733
Query: 766 SGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHG-QGPSQPCGAV- 823
+G +GP GP+G+ P SG P +GP G+ + G GP G +
Sbjct: 734 AGGHGPD----GPKGS----PGPSGTPGD--TGPPGLQGMPGERGIAGTPGPKGDRGGIG 783
Query: 824 PLGRMPSAGMQN-RPFPGNMSSMTPSSPGMSQQGGPG----MGPPMPTVN---RKAQEAA 875
G +AG R PG + P+ P ++G PG +GPP N R
Sbjct: 784 EKGAEGTAGNDGARGLPGPLGPPGPAGP-TGEKGEPGPRGLVGPPGSRGNPGSRGENGPT 842
Query: 876 AAVMQAAANSAQSRQG-----SFPGM-------NQSGLMASSSPYS-QPMNNSSSLMNTQ 922
AV A + G PG GL S P+ + TQ
Sbjct: 843 GAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQ 902
Query: 923 APPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGK--EEGTP--QPESKSKDSYS 978
PP + SA VG PG + P P G+ +EG P + + S
Sbjct: 903 GPPGATG---FPGSAGRVG-----PPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVG 954
Query: 979 SQGISQPP-------TPGNLPVPSPMSP-------SSASISSFHGDESDSISSPGWPKTP 1024
+G + PP PG P P P I G + PG P
Sbjct: 955 DRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGER-GMPGLPGPA 1013
Query: 1025 SSP-KSSSSTTTGEK 1038
+P K + TG+K
Sbjct: 1014 GTPGKVGPTGATGDK 1028
Score = 63.5 bits (153), Expect = 2e-09
Identities = 150/617 (24%), Positives = 191/617 (30%), Gaps = 99/617 (16%)
Query: 82 LGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGR 141
L G G A GPD + G S G PPG L PG+ A G P G +
Sbjct: 727 LPGEKGMAGGHGPDGPK---GSPGPSGTPGDTGPPG--LQGMPGERGIA----GTP-GPK 776
Query: 142 YEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG----GPGGRAGPCFDQH 197
+ G+G G + G G +P G A P GP G GP +
Sbjct: 777 GDRGGIGEKGAEGT-----AGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRG 831
Query: 198 G----GQQSPGMGMMHSASAAAAGAPGSM----DPLQNSHEGYPNSQCNHYPGYSRPGAG 249
G+ P + + G PG +P Q G P Q G
Sbjct: 832 NPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQ----------GLA 881
Query: 250 GGGGGGGGGG--GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307
G G G G G GG G G GA G A A A G G G G
Sbjct: 882 GSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPP 941
Query: 308 GVLSSPRQQGGGMMMGPGG--GGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLL 365
G+ P G GP G GG G P G T Q
Sbjct: 942 GLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPG--------PDGPPGPAGTTGQRG 993
Query: 366 TSPSPMMRSYGGSYPEYSSPSAPPP--PPSQPQSQAAAAGAAAGGQQAAAGM-GLGKDMG 422
P G E P P P P + A G G G + G
Sbjct: 994 IVGMP------GQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPG 1047
Query: 423 AQYAAASPAWAAAQQRSHPAMSPGTPGPT-MGRSQGSPMDPMVMKRPQLYGMGSNPHSQP 481
+ A + G PGP + SQG+P P + P G +P S+
Sbjct: 1048 PEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRG 1107
Query: 482 QQSSPYPGGSYGPPGPQRYPIGIQG-------------RTPGAMAGMQYPQQQMPPQYGQ 528
P G G PGPQ P G +G R + G+ P P G+
Sbjct: 1108 PIGPPGRAGKRGLPGPQG-PRGDKGDHGDRGDRGQKGHRGFTGLQGLPGP----PGPNGE 1162
Query: 529 QGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQP-----QQDMSQEGYGTRSQ 583
QG +G P+ + P P P + P P + EG
Sbjct: 1163 QGSAGI----PGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPG 1218
Query: 584 PPLAPGKPNH------EDLNLIQQERPSSLPDLS---GSIDD---LPTGTEATLSSAVS- 630
PP PG P H + + + P LP+ + + DD G ATL S S
Sbjct: 1219 PPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTDPGVHATLKSLSSQ 1278
Query: 631 ASGSTSSQGDQSNPAQS 647
S G + +PA++
Sbjct: 1279 IETMRSPDGSKKHPART 1295
>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
Length = 1604
Score = 100 bits (249), Expect = 2e-20
Identities = 245/999 (24%), Positives = 309/999 (30%), Gaps = 209/999 (20%)
Query: 93 GPDMEQPQHGGAKDSAAGGQADPPGPP------LLSKPGDEDDAPPKMGEPAGGRYEHPG 146
GP ++ G G+ PPG P L PGD P G+ G PG
Sbjct: 429 GPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDK--GSSGIPG 486
Query: 147 LGALGTQQPPVAVPGGGGGPAAV----PE-FNNYYG------------SAAPASGGPG-- 187
G + V G G P V PE F N+ G PA G PG
Sbjct: 487 KEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQ 546
Query: 188 ---GRAG-PCFD-------QH--------GGQQSPGMGMM----------------HSAS 212
G G PC QH G SPG G+ +
Sbjct: 547 GIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGE 606
Query: 213 AAAAGAPGSMDPLQNSH-EGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGA 271
A AG+PG P+ + +G C P S G G G G G G
Sbjct: 607 AGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF 666
Query: 272 GAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAA- 330
G G A AG G G G++ G+ P QG G G G
Sbjct: 667 GLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTA 726
Query: 331 --SLSKAAAGSAAGGFQRFAGQNQHPSGA----------------TPTLNQLLTSPSPMM 372
SL A Q Q P G P L + P P
Sbjct: 727 CPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPG 786
Query: 373 RSYGGSYPEYSSPSAP-------PPPPSQPQSQAAAAGA----AAGGQQAAAGMGLGKDM 421
R G E +P P P P P + A G+ A G G +
Sbjct: 787 RGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPP 846
Query: 422 GAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQP 481
G P G PG SQG + + P L+ MGS+ P
Sbjct: 847 GRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLW-MGSSWQPGP 905
Query: 482 QQSSPYPGGSYGPPGPQRYPIGIQGRTPG-----AMAGMQYPQQQMP-PQYGQQGVSGYC 535
Q P G GPPGP P G+QG PG G+ +P Q+ + + G C
Sbjct: 906 QG----PPGIPGPPGPPGVP-GLQG-VPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDC 959
Query: 536 QQGQQ--PYYSQQ---------PQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGY------ 578
QGQ+ P Y + P P L AQ S + R + + + EG
Sbjct: 960 VQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGS 1019
Query: 579 ----------GTRSQ-----------------PPLAPGKPNHEDLNLIQQERPSSLPDLS 611
G R + PP PG L +Q ER L L+
Sbjct: 1020 PGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGER--GLTGLT 1077
Query: 612 GSIDD-----LPTGTEAT----LSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPG 662
G + P AT L G T S G++ P P S L PG
Sbjct: 1078 GDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPG-----PPGSEGLPGPPG 1132
Query: 663 GPSPSPVGSPVGSNQSRS-----------GPISPASIPGSQMPPQPPGSQSESSSHPALS 711
P P G++ + GP P PG P PPG Q+E S
Sbjct: 1133 PAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRG 1192
Query: 712 QSPMPQERG--FMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMH-AGISSFQ-QSNSSG 767
S +P G G Q + + P + P P G G F+ ++ G
Sbjct: 1193 PSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPG 1252
Query: 768 TYGPQ--MSQYGPQGNYSRPPAYSGVPSA--SYSGPGPGMGISANNQMHGQGPSQPCGAV 823
GP+ + GP G+ RP A G P A PGP + GP+ AV
Sbjct: 1253 LPGPKGDCGKPGPPGSTGRPGA-EGEPGAMGPQGRPGPPGHVGPPGPPGQPGPA-GISAV 1310
Query: 824 PL-------GRMPSAGMQNRPFPGNMSSMTPSSPG----MSQQGGPG----MGPPMPTVN 868
L G AG+ +P P P PG ++G PG GPP P
Sbjct: 1311 GLKGDRGATGERGLAGLPGQPGPPGHPG-PPGEPGTDGAAGKEGPPGKQGFYGPPGP--- 1366
Query: 869 RKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSP 907
K AA Q + R G G +SG M P
Sbjct: 1367 -KGDPGAAG--QKGQAGEKGRAGMPGGPGKSGSMGPVGP 1402
Score = 78.2 bits (191), Expect = 8e-14
Identities = 125/480 (26%), Positives = 144/480 (30%), Gaps = 76/480 (15%)
Query: 84 GAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLL-------------SKPGDEDD- 129
G G PGP E+ G S G PPGPP + KPG D
Sbjct: 1171 GKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDP 1230
Query: 130 ---APPKMGEPAG--GRYEHPGL-GALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPAS 183
PP + P G G+ HPGL G G P PG G P A E P +
Sbjct: 1231 GPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKP-GPPGSTGRPGAEGE---------PGA 1280
Query: 184 GGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPL-QNSHEGYPNSQCNHYPG 242
GP GR GP H G P G A +A G G + G P PG
Sbjct: 1281 MGPQGRPGP--PGHVGPPGP-PGQPGPAGISAVGLKGDRGATGERGLAGLPGQP--GPPG 1335
Query: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG 302
+ P G G G G G G G G G A A AG GG G G
Sbjct: 1336 HPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSG 1395
Query: 303 SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAG--GFQRFAGQNQHPSGATPT 360
S G ++G GP G + G +RF Q
Sbjct: 1396 SMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERM 1455
Query: 361 LNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGM----- 415
PM + P P P P S G+Q G+
Sbjct: 1456 AYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPG 1515
Query: 416 --GLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGM 473
G D+G A + PG PGP QG P YG
Sbjct: 1516 TKGEKGDIGIGIAGENGL-------------PGPPGP-----QGPPG----------YGK 1547
Query: 474 GSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSG 533
QQ P G GPPGP P P G +QQ PP +G G
Sbjct: 1548 MGATGPMGQQGIP---GIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKTMKGPFG 1604
Score = 76.6 bits (187), Expect = 2e-13
Identities = 207/869 (23%), Positives = 271/869 (31%), Gaps = 129/869 (14%)
Query: 87 GGAPQPGPDMEQPQHGGAKDSAAGGQADP--PGPPLLSKPGDEDDAPPKMGEPAGGRYEH 144
G QPGP EQ G + G P GPP L E P + + G
Sbjct: 739 GRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGA 798
Query: 145 PGLGALGTQQPPVAVPG-----GGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGG 199
PGL + P PG G G V G + GP GR G Q G
Sbjct: 799 PGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQ-GQTGL 857
Query: 200 QQSPGMGMMHSASAAAAGAPGSMD-PLQNS--HEGYPNSQCNHYPGYSRPGAGGGGG--G 254
+ +PG G PG P Q G P + +PG G G G
Sbjct: 858 RGTPG----EKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPG 913
Query: 255 GGGGGGGSGGGGGGGGAGAGGA-GAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSP 313
G G G G G G G G A + G G A G L
Sbjct: 914 PPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEK 973
Query: 314 RQQGGGMMMG-PGGGGAA----SLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSP 368
++G + G PG A SL + A A G ++ G + L P
Sbjct: 974 GEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGD------NSEGDPGCVGSPG--LPGP 1025
Query: 369 SPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAA-GGQQAAAGM-GLGKDMGAQYA 426
+ G P S PP P P A G+ G Q G+ GL D G
Sbjct: 1026 PGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGP 1085
Query: 427 AASPAW-------------------AAAQQRSHPAMS-----PGTPGPTMGRSQGSPMDP 462
P + +A ++ P PG PGP R + P
Sbjct: 1086 PGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGN 1145
Query: 463 MVMKRPQLYGMGSNPHSQPQQSSPYPG--GSYGPPGPQRYPIGIQG-RTPGAMAGMQYPQ 519
K Q + G P +PG GS GPPGPQ G +G R P + G P
Sbjct: 1146 SGEKGDQGF-QGQPGFPGPPGPPGFPGKVGSPGPPGPQAEK-GSEGIRGPSGLPGSPGPP 1203
Query: 520 QQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYG 579
P G G+ G + +P P P PP P + P + G
Sbjct: 1204 GP-PGIQGPAGLDGLDGKDGKPGLRGDPGPAG-PPGLMGPPGFKGKTGHPGLPGPKGDCG 1261
Query: 580 TRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDL-PTGTEATLS-SAVSASGSTSS 637
+ PP + G+P E P P G + P G SAV G +
Sbjct: 1262 -KPGPPGSTGRPGAEGEPGAMG--PQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGA 1318
Query: 638 QGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQP 697
G++ L+ +PG P P P G G PG Q P
Sbjct: 1319 TGERG--------------LAGLPGQPGPPGHPGPPGE-PGTDGAAGKEGPPGKQGFYGP 1363
Query: 698 PGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQ----------QTGPSMSPH- 746
PG + + + Q+ G G ++ M GP GPS SP
Sbjct: 1364 PGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGL 1423
Query: 747 PSPGGQM-----HAGISSFQQSNSSGTYGPQMSQYGPQGNYSR----------PPAYSGV 791
P G M + I F + + +M+ Y + + PP G
Sbjct: 1424 PGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGA 1483
Query: 792 PSASYSGPGPGM----GISANNQMHG----QGPSQPCGAVPLGRMPSAGMQNRPFP---- 839
P + PG+ G + G G G + +G G+ P P
Sbjct: 1484 PGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPP 1543
Query: 840 --GNMSSMTPSSPGMSQQGGPGM-GPPMP 865
G M + P M QQG PG+ GPP P
Sbjct: 1544 GYGKMGATGP----MGQQGIPGIPGPPGP 1568
Score = 75.5 bits (184), Expect = 6e-13
Identities = 166/677 (24%), Positives = 211/677 (31%), Gaps = 129/677 (19%)
Query: 79 NNSLGGAG--GGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGE 136
+NS G G G PGP Q G G PPGP + PG P +G
Sbjct: 1008 DNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGP--IGPPG----FPGAVGS 1061
Query: 137 PA-GGRYEHPGLGALGTQQPPVAVPG-----GGGGPAAVPEFNNYYGSAAPASGGPGGRA 190
P G GL L + PG G GP +P G S G G
Sbjct: 1062 PGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTG--SAGEKGEP 1119
Query: 191 GPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGG 250
GP G + PG AG G P NS E + PG+ P
Sbjct: 1120 GP----PGSEGLPG-------PPGPAGPRGERGPQGNSGEK-GDQGFQGQPGFPGPPGPP 1167
Query: 251 GGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVL 310
G G G G G G G G + G G G G G+
Sbjct: 1168 GFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLR 1227
Query: 311 SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSP 370
P G +MGP G F G+ HP P + P
Sbjct: 1228 GDPGPAGPPGLMGPPG--------------------FKGKTGHPGLPGPKGDCGKPGPPG 1267
Query: 371 MMRSYGGS-YPEYSSPSAPPPPPSQ-----PQSQAAAAGAAAGGQQAAAGMGLGKDMGAQ 424
G P P P PP P Q AG +A +GL D GA
Sbjct: 1268 STGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISA--------VGLKGDRGA- 1318
Query: 425 YAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQS 484
+R + PG PGP G P P G + ++
Sbjct: 1319 ----------TGERGLAGL-PGQPGPP-----GHPGPP---------GEPGTDGAAGKEG 1353
Query: 485 SPYPGGSYGPPGPQRYP--------IGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQ 536
P G YGPPGP+ P G +GR M G M P G G +G
Sbjct: 1354 PPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRA--GMPGGPGKSGSMGP-VGPPGPAGERG 1410
Query: 537 QGQQPYYSQQPQPPHLPPQAQYLPSQSQ-QRYQPQQ-----DMSQEGYGTRSQPPL---- 586
P S P P +P + + + +R+ Q+ D Y +R Q P+
Sbjct: 1411 HPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAA 1470
Query: 587 APGKPNH--EDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNP 644
APG+P +D + P S P L G I G E G ++G++ +
Sbjct: 1471 APGRPGPPGKDGAPGRPGAPGS-PGLPGQI-----GREGR-QGLPGVRGLPGTKGEKGDI 1523
Query: 645 AQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQP---PGSQ 701
+ P GP P P G P +GP+ IPG PP P PG
Sbjct: 1524 GIGIAGENGLP-------GP-PGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKA 1575
Query: 702 SESSSHPALSQSPMPQE 718
+ PM Q+
Sbjct: 1576 GHCNPSDCFGAMPMEQQ 1592
Score = 72.4 bits (176), Expect = 5e-12
Identities = 192/862 (22%), Positives = 264/862 (30%), Gaps = 162/862 (18%)
Query: 246 PGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSA 305
P G G G G G GG G G G G G G G +
Sbjct: 388 PSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAG 447
Query: 306 GYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAA----------GGFQRFAGQNQHPS 355
G P G G+ PG G K GS+ G G+ P
Sbjct: 448 EPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPC 507
Query: 356 GATPTLNQLLTSPSPMMRSYG--GSYPEYSSPSAPPPPPSQPQSQ---------AAAAGA 404
PTL P G G P P P P Q + +
Sbjct: 508 EVCPTL------PEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSS 561
Query: 405 AAGGQQAAAGMGLGKDMGA--------QYAAASPAWAAAQ---QRSHPAMSPGTPGPT-- 451
G Q + G D+G+ A P + + PA SPG PGP
Sbjct: 562 VVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGP 621
Query: 452 --MGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPI-GIQGRT 508
+ ++G P +P P L + + P P G G PGP + + G QG+
Sbjct: 622 AGIKGAKGEPCEPC----PALSNLQDG--DVRVVALPGPSGEKGEPGPPGFGLPGKQGKA 675
Query: 509 PGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQP-----------PHLPPQAQ 557
Q P G G +G +P P P L
Sbjct: 676 GERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVT 735
Query: 558 YLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDL 617
+ + Q P+ + EG G PGKP LP + G
Sbjct: 736 DMAGRPGQP-GPKGEQGPEGVG-------RPGKPGQ-----------PGLPGVQG----- 771
Query: 618 PTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQ 677
P G + G G Q P +P L I G P P P G
Sbjct: 772 PPGLK----------GVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKG 821
Query: 678 SRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGP- 736
++ P + G+ P PPG+ S S P G T + GP
Sbjct: 822 AQGSP----GVKGATGPVGPPGA----------SVSGPPGRDGQQGQTGLRGTPGEKGPR 867
Query: 737 -QQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSAS 795
++ P PS G + +G+ + G + Q GPQG PP G P
Sbjct: 868 GEKGEPGECSCPSQGDLIFSGM-----PGAPGLWMGSSWQPGPQG----PPGIPGPPGP- 917
Query: 796 YSGPG-PGM-GISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPG-- 851
PG PG+ G+ NN + P QP LG +P + G+ + PG
Sbjct: 918 ---PGVPGLQGVPGNNGL----PGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYL 970
Query: 852 --MSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPG-MNQSGLMASSS-P 907
++G G+ P +P ++ AQ + A + PG + GL P
Sbjct: 971 VEKGEKGDQGI-PGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLP 1029
Query: 908 YSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTP 967
+ + + PP + P + S GL + GE L L D E G P
Sbjct: 1030 GQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQ--GERGL-TGLTGDKGEPGPP 1086
Query: 968 -------------QPESKSKDSY--SSQGISQPPTPGNLPVPSPMSPSS-------ASIS 1005
P K + Y S+ +P PG+ +P P P+ S
Sbjct: 1087 GQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNS 1146
Query: 1006 SFHGDESDSISSPGWPKTPSSP 1027
GD+ PG+P P P
Sbjct: 1147 GEKGDQGFQ-GQPGFPGPPGPP 1167
Score = 33.9 bits (76), Expect = 1.8
Identities = 77/327 (23%), Positives = 109/327 (33%), Gaps = 66/327 (20%)
Query: 1163 PSPANSGSLQGPQ-TPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDP 1221
P P G +QGPQ P + G + +PG PP P Q +P G + +T V P
Sbjct: 782 PGPPGRG-VQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSP--GVKGATGPVGPP 838
Query: 1222 FSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQG 1281
+ VS P QQG + G+R PG P +G
Sbjct: 839 GASVSG---------PPGRDGQQGQT------------------GLRGTPGEKGPRGEKG 871
Query: 1282 QMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYG 1341
+ S + SG G+ G+S+ +P Q PG P G P
Sbjct: 872 EPGECSCPSQGDLIFSGMPGAPGLWM------GSSW----QPGPQGPPGIPGPPGPPGVP 921
Query: 1342 GHQ--PGL--YPQQPNYKRHMDGMYGPPAKRH----------EGDMYNMQYSSQQQEMYN 1387
G Q PG P QP + + P ++H +G + Y ++ E +
Sbjct: 922 GLQGVPGNNGLPGQPGLTAELGSL---PIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGD 978
Query: 1388 QYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMW 1447
Q G D Q R R + + G P G + S GP
Sbjct: 979 QGIPGVPGLDN---CAQCFLSLERPRAEEARGDNSEGDP-----GCVGSPGLPGPPGLPG 1030
Query: 1448 AARNDMPYPYQNRQGPGGPTQAPPYPG 1474
+ P + GP GP P +PG
Sbjct: 1031 QRGEEGPPGMRGSPGPPGPIGPPGFPG 1057
Score = 33.1 bits (74), Expect = 3.1
Identities = 68/327 (20%), Positives = 107/327 (32%), Gaps = 44/327 (13%)
Query: 682 PISPASIPGSQMPPQPPGSQSESSS--HPALSQSPMPQERGFMAGTQRNPQMAQYGPQQT 739
P P G + P PPGS+ E + + + SP + + GP
Sbjct: 332 PSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGL 391
Query: 740 GPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQG-----NYSRPPAYSGVPSA 794
S G + GI ++ GP+G + P +G P
Sbjct: 392 PGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGP 451
Query: 795 SYSGPGPGMGISANNQMHGQGPSQPCGAV-PLGRMPSAGMQNRPFPGNMSSMTPSSPGMS 853
PG+G+ P P G P G S+G+ + PG P PG+
Sbjct: 452 PGLPGPPGIGLPGT-------PGDPGGPPGPKGDKGSSGIPGKEGPGG----KPGKPGVK 500
Query: 854 QQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMN 913
+ G PT+ Q + P G+ +P
Sbjct: 501 GEKGDPC-EVCPTLPEGFQNFVG--LPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCL 557
Query: 914 NSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKS 973
+ SS++ Q +V+S+ AS D+ SPG LP +A G P + +
Sbjct: 558 SCSSVVGAQ--------HLVSSTGAS---GDVGSPGFGLPGLPGRA-----GVPGLKGE- 600
Query: 974 KDSYSSQGISQPPTPGNLPVPSPMSPS 1000
K ++ G + P P P P+ P+
Sbjct: 601 KGNFGEAGPAGSPGP-----PGPVGPA 622
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 99.4 bits (246), Expect = 4e-20
Identities = 95/296 (32%), Positives = 117/296 (39%), Gaps = 43/296 (14%)
Query: 66 QQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPG 125
Q++Q Q P+ + GG GGG G GG GG G S G
Sbjct: 4 QKKQPTPQPPVDCVKTSGGGGGGGGSGG--------GGCGFFGGGGSG---GGSSGSGCG 52
Query: 126 DEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASG- 184
G GG G G +G G GGG +++ GS+ SG
Sbjct: 53 YSGGGGYSGGGCGGGSSGGGGGGGIG---------GCGGGSGGSVKYSGGGGSSGGGSGC 103
Query: 185 -GPGGRAGPCFDQHGGQQSPG-MGMMHSASAAAAGAPGSMDPLQNSHEGYPNS--QCNHY 240
GG CF GG S G G S ++G G + G+ QC Y
Sbjct: 104 FSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSG--GGSGCFSSGGGGFSGQAVQCQSY 161
Query: 241 PGYSRPGAGGGGGG----GGGGG---GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAA- 292
G S G+ GGG G GGGGG G SGGG G GG +GG+G+G V++ + A
Sbjct: 162 GGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAP 221
Query: 293 --GGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSK---AAAGSAAGG 343
GGG GG S G G SS GGG G GGG + S + GS GG
Sbjct: 222 QPSYGGGSSGGGGSGGSGCFSS---GGGGGSSGCGGGSSGIGSGCIISGGGSVCGG 274
Score = 89.7 bits (221), Expect = 3e-17
Identities = 67/212 (31%), Positives = 89/212 (41%), Gaps = 25/212 (11%)
Query: 247 GAGGGGGGGGGGGGGSGGGGGGGGAGAGGAG--AGAVAAAAAAAAAAAGGGGGGGYGGSS 304
G GGGGG GGGG G GGGG GGG+ G G G + ++GGGGGGG GG
Sbjct: 22 GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCG 81
Query: 305 AGYGVLSSPRQQGGGMMMG-------PGGGGAASLSKAAAGSAAGGFQRFA----GQNQH 353
G G S + GGG G GGGG+ S GS+ GG F+ G +
Sbjct: 82 GGSG--GSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGG 139
Query: 354 PSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAA 413
SG + + + +SYGG SS S S G+ G +
Sbjct: 140 GSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGG-----SGCFSSGGGGGSVCGYSGGGS 194
Query: 414 GMGLGKDMGAQYAAASPAWAAAQQRSHPAMSP 445
G G G G + + ++QQ + + +P
Sbjct: 195 GCGGGSSGG-----SGSGYVSSQQVTQTSCAP 221
Score = 89.0 bits (219), Expect = 5e-17
Identities = 68/227 (29%), Positives = 88/227 (38%), Gaps = 18/227 (7%)
Query: 82 LGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMG--EPAG 139
+GG GGG+ G ++ GG+ +G + G G + G G
Sbjct: 77 IGGCGGGS---GGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGG 133
Query: 140 GRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGG 199
G G G + GGGG + +Y G + SGG G CF GG
Sbjct: 134 GGSSGGGSGCFSS--------GGGGFSGQAVQCQSYGGVS---SGGSSGGGSGCFSSGGG 182
Query: 200 QQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGG 259
S G S G+ G S + + C P Y G+ GGGG GG G
Sbjct: 183 GGSV-CGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGG-GSSGGGGSGGSGC 240
Query: 260 GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG 306
SGGGGG G G G +G G+ + + GG GGG GGSS G
Sbjct: 241 FSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVG 287
Score = 85.1 bits (209), Expect = 7e-16
Identities = 76/243 (31%), Positives = 94/243 (38%), Gaps = 41/243 (16%)
Query: 152 TQQPPV----AVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGM 207
T QPPV GGGGG + ++G G G G + GG G G
Sbjct: 9 TPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCG--YSGGGGYSGGGCGG 66
Query: 208 MHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGG------GGGG 261
S G G C G S +GGGG GGG GGGG
Sbjct: 67 GSSGGGGGGGIGG----------------CGGGSGGSVKYSGGGGSSGGGSGCFSSGGGG 110
Query: 262 SG----GGGG--GGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQ 315
SG GGGG GGG+G +G G ++ + ++GGGG G YG +SS
Sbjct: 111 SGCFSSGGGGSSGGGSGCFSSGGGG-SSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGS 169
Query: 316 QGGGM-MMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRS 374
GGG GGGG + + GS GG + + S T Q +P P S
Sbjct: 170 SGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVT--QTSCAPQP---S 224
Query: 375 YGG 377
YGG
Sbjct: 225 YGG 227
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 98.6 bits (244), Expect = 6e-20
Identities = 251/1066 (23%), Positives = 311/1066 (29%), Gaps = 211/1066 (19%)
Query: 75 PISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAG-----------GQADPPGPPLLS- 122
P G AG + P P+ D AG G + PPGPP
Sbjct: 602 PAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDG 661
Query: 123 KPGDEDDAPPK--MGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180
+ GD+ + P+ GEP G R G LG + PP GP P G
Sbjct: 662 ERGDDGEVGPRGLPGEP-GPR------GLLGPKGPP--------GPPGPPGVTGMDGQPG 706
Query: 181 PASG-GPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNH 239
P GP G GP G Q +PG + A G PG PL G P
Sbjct: 707 PKGNVGPQGEPGP----PGQQGNPGAQGLPGPQGAI-GPPGEKGPL--GKPGLPGM---- 755
Query: 240 YPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGG 299
PG P G G G GG G G G G G A G G G
Sbjct: 756 -PGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDG 814
Query: 300 YGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATP 359
+ G G+ + G GP G K G + P G
Sbjct: 815 FPGFKGDMGIKGDRGEIGPP---GPRGEDGPEGPKGRGGPNG---------DPGPLGPPG 862
Query: 360 TLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGK 419
+L P YP P P P + G G+ G
Sbjct: 863 EKGKLGVPGLP-------GYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRG----- 910
Query: 420 DMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHS 479
Q P + P G PGP P P + P +
Sbjct: 911 ----QRGPTGP-----RGERGPRGITGKPGPKGNSGGDGPAGPPGERGP----------N 951
Query: 480 QPQQSSPYPGGSYGPPGP-----------QRYPIGIQGRT----PGAMAGMQYPQQQMPP 524
PQ + +PG GPPGP QR G QG+T P + G Q P + P
Sbjct: 952 GPQGPTGFPGPK-GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGP 1010
Query: 525 QYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQP 584
G++G P PP PP Q LP + + + D G + P
Sbjct: 1011 M-GERG---------------HPGPPG-PPGEQGLPGLAGKE-GTKGDPGPAGLPGKDGP 1052
Query: 585 PLAPGKPNHEDL-------NLIQQERPSSLPDLSGSIDDL-PTGTEATLS--SAVSASGS 634
P G P L L E P P +GS + P G + G
Sbjct: 1053 PGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGP 1112
Query: 635 TSSQGDQSNPAQS-PFSPHASPHLSSIPGGPSPS-PVGSPVGSNQS----RSGPISPASI 688
G++ P + P P L G P P+ PVG P G
Sbjct: 1113 PGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGD 1172
Query: 689 PGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMA-GTQRNPQMAQYGPQQTGP-SMSPH 746
G Q PP P G Q P RG Q+ + + P GP +
Sbjct: 1173 KGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGL 1232
Query: 747 PSPGGQMHAGISSFQQ-----------SNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSAS 795
P P G+ Q S + G GPQ GP G P A
Sbjct: 1233 PGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQ----GPPGGIGNPGAVGEKGEPG 1288
Query: 796 YSG----PGPGMGISANNQMHGQGPSQPCGAV----PLGRMPSAGMQNRP----FPGNMS 843
+G PG G + +G S P GA P G G + P FPG+
Sbjct: 1289 EAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPG 1348
Query: 844 SMTPSSPGMSQQGGPG-----------------------------MGPPMPTVNRKAQEA 874
P PG + Q GP GPP P Q
Sbjct: 1349 P--PGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGE 1406
Query: 875 AAAVMQAAANSAQSRQGSF-----PGM-NQSGLMASSSPYSQPMNNSSSLMNTQAPPYSM 928
A +A + G PG GL P + S PP M
Sbjct: 1407 KGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSP--GPDGPPGPM 1464
Query: 929 APAMVNSSAASVG-LADMMSPGESKLPLPLKADGK--EEGTPQPESKSKDSYSSQGISQP 985
P + G + PG L P G+ + G P P+ S QGI+ P
Sbjct: 1465 GPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPK-GEQGITGP 1523
Query: 986 PTPGNLP----VPSPMSPSSASISSFHGDESDSISSPGWPKTPSSP 1027
P P +P P P A SS PG P P P
Sbjct: 1524 SGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPP 1569
Score = 93.6 bits (231), Expect = 2e-18
Identities = 244/988 (24%), Positives = 304/988 (30%), Gaps = 175/988 (17%)
Query: 58 QQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG 117
Q+ Q Q QQ + + L G G PG + + G G PPG
Sbjct: 542 QESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPG 601
Query: 118 PPLLSKPG-------DEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVP 170
P KPG D P P G R GL L ++ P G GP P
Sbjct: 602 P--AGKPGRRGRAGSDGARGMPGQTGPKGDR-GFDGLAGLPGEKGHRGDP-GPSGPPGPP 657
Query: 171 EFNNYYGS-------AAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMD 223
+ G P GP G GP G PG+ M G G++
Sbjct: 658 GDDGERGDDGEVGPRGLPGEPGPRGLLGP-KGPPGPPGPPGVTGMD----GQPGPKGNVG 712
Query: 224 PLQNSHEGYPNSQCNHYPGYSRPGAGG--GGGGGGGGGGGSGGGGGGGGAGAGGAGAGAV 281
P G P Q N PGA G G G G G G G G G GA
Sbjct: 713 P--QGEPGPPGQQGN-------PGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGAD---- 759
Query: 282 AAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGP----GGGGAASLSKAAA 337
G G G G G G P QG GP G G L
Sbjct: 760 --------GPPGHPGKEGPPGEKGGQG---PPGPQGPIGYPGPRGVKGADGIRGLKGTKG 808
Query: 338 GSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQS 397
GF F G G + + P P P+ P P P
Sbjct: 809 EKGEDGFPGFKGD----MGIKGDRGE-IGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGE 863
Query: 398 QAAAAGAAAGGQQAAAGM-GLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQ 456
+ G+ G+ G G + + P + A +PG PGP R Q
Sbjct: 864 K---------GKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGP---RGQ 911
Query: 457 GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRT--PGAMAG 514
P P + P+ G+ P + P GPPG +R P G QG T PG
Sbjct: 912 RGPTGPRGERGPR--GITGKPGPKGNSGGDGPA---GPPG-ERGPNGPQGPTGFPGPKGP 965
Query: 515 MQYP-QQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDM 573
P + +P GQ+G +G+ QG+ + P PP + PQ
Sbjct: 966 PGPPGKDGLPGHPGQRGETGF--QGK----TGPPGPPGV--------------VGPQGPT 1005
Query: 574 SQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASG 633
+ G P PG P + LP L+G A L G
Sbjct: 1006 GETGPMGERGHPGPPGPPGEQ-----------GLPGLAGKEGTKGDPGPAGLPGKDGPPG 1054
Query: 634 STSSQGDQSNPAQSPFSPHASPHLSSIPGGPS-PSPVGSPVGSNQSRSGPISPASIPGSQ 692
GD+ P P + L G P P P GSP + +G P IPG
Sbjct: 1055 LRGFPGDRGLP-----GPVGALGLKGNEGPPGPPGPAGSP--GERGPAGAAGPIGIPGRP 1107
Query: 693 MPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYG-PQQTGPSMSPHPSPGG 751
P PPG E + P E+G R+ G P GP + P G
Sbjct: 1108 GPQGPPGPAGEKGA---------PGEKGPQGPAGRDGLQGPVGLPGPAGP-VGPPGEDGD 1157
Query: 752 QMHAGISSFQQSNSSGTYGPQ--MSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANN 809
+ G Q S G G Q GPQG +P PS + PGP
Sbjct: 1158 KGEIGEPG--QKGSKGDKGEQGPPGPTGPQGPIGQPG-----PSGADGEPGPRGQQGLFG 1210
Query: 810 QMHGQGP---SQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSP--GMSQQGGPG----M 860
Q +GP P G V L +P + + G++ M P P G PG
Sbjct: 1211 QKGDEGPRGFPGPPGPVGLQGLPGPPGE-KGETGDVGQMGPPGPPGPRGPSGAPGADGPQ 1269
Query: 861 GPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMN 920
GPP N A +A G + G S P + ++
Sbjct: 1270 GPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGP-----SGAAGPPG 1324
Query: 921 TQAPPYSMAPAMVNSSAASVGL-ADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSS 979
+ PP P S VG D PGE P P DG P K D
Sbjct: 1325 PKGPPGDDGP---KGSPGPVGFPGDPGPPGE---PGPAGQDG------PPGDKGDDGEPG 1372
Query: 980 QGISQPPT--------PGNLPVPSPMSP 999
Q S PT PG P P P
Sbjct: 1373 QTGSPGPTGEPGPSGPPGKRGPPGPAGP 1400
Score = 93.2 bits (230), Expect = 3e-18
Identities = 226/954 (23%), Positives = 282/954 (29%), Gaps = 169/954 (17%)
Query: 111 GQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPP--VAVPGGGGGPA- 167
G+ G P + +PG + PP PAG G GT P V PG G P
Sbjct: 450 GEKGQKGEPAIIEPGMLIEGPPGPEGPAGLP------GPPGTMGPTGQVGDPGERGPPGR 503
Query: 168 -AVPEFNNYYGSAA-----PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGS 221
+P + G P G GG AG Q+S ++ A A G G
Sbjct: 504 PGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGP 563
Query: 222 MDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAV 281
M PG P GG G G G G G G G G
Sbjct: 564 MG-------------LTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPG--- 607
Query: 282 AAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAA 341
A + A G G G G G+ P ++G GP G G
Sbjct: 608 RRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSG---------PPGPPG 658
Query: 342 GGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAA 401
+R P G L P P R G P PP PP P
Sbjct: 659 DDGERGDDGEVGPRG-------LPGEPGP--RGLLG-------PKGPPGPPGPP------ 696
Query: 402 AGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMD 461
GQ G ++G Q P Q+ +P + G PGP + G P +
Sbjct: 697 GVTGMDGQPGPKG-----NVGPQGEPGPPG-----QQGNPG-AQGLPGPQ--GAIGPPGE 743
Query: 462 PMVMKRPQLYGM--GSNPHSQPQQSSPYPG--GSYGPPGPQRYPIGIQGRTPGAMAGMQY 517
+ +P L GM P P + P PG G GPPGPQ PIG G A
Sbjct: 744 KGPLGKPGLPGMPGADGPPGHPGKEGP-PGEKGGQGPPGPQG-PIGYPGPRGVKGADGIR 801
Query: 518 PQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEG 577
+ + G+ G G+ +G + + P+ + P + R P D G
Sbjct: 802 GLKGTKGEKGEDGFPGF--KGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLG 859
Query: 578 YGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSS 637
PP GK +P L G A+G
Sbjct: 860 ------PPGEKGK--------------LGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGG 899
Query: 638 QGDQSNPA----QSPFSPHASPHLSSIPGGPSP-------SPVGSPVGSNQSRSGPISPA 686
+G P + P P I G P P P G P + +GP P
Sbjct: 900 RGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPP--GERGPNGPQGPT 957
Query: 687 SIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQ----QTGP- 741
PG + PP PPG HP E GF T GPQ +TGP
Sbjct: 958 GFPGPKGPPGPPGKDG-LPGHPG-----QRGETGFQGKTGPPGPPGVVGPQGPTGETGPM 1011
Query: 742 SMSPHPSPGGQM-HAGISSFQQSNSSGTYGPQMSQYGPQG--NYSRPPAYSGVP-SASYS 797
HP P G G+ + GT G GP G PP G P
Sbjct: 1012 GERGHPGPPGPPGEQGLPGL--AGKEGTKGDP----GPAGLPGKDGPPGLRGFPGDRGLP 1065
Query: 798 GPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGG 857
GP +G+ N GP P G+ P R P+ PG P P ++G
Sbjct: 1066 GPVGALGLKGNE--GPPGPPGPAGS-PGERGPAGAAGPIGIPGRPGPQGPPGPA-GEKGA 1121
Query: 858 PG-MGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSS 916
PG GP P Q A G + + G S +
Sbjct: 1122 PGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGE------ 1175
Query: 917 SLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESK---- 972
Q PP P G P + K D G P P
Sbjct: 1176 -----QGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQ 1230
Query: 973 -------SKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPG 1019
K G PP P P P PS A + I +PG
Sbjct: 1231 GLPGPPGEKGETGDVGQMGPPGP-----PGPRGPSGAPGADGPQGPPGGIGNPG 1279
Score = 89.7 bits (221), Expect = 3e-17
Identities = 176/701 (25%), Positives = 223/701 (31%), Gaps = 143/701 (20%)
Query: 83 GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPP----LLSKPGDEDDA-------- 130
G +GG P GP E+ +G + G PPGPP L PG +
Sbjct: 934 GNSGGDGPA-GPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 992
Query: 131 --PPKMGEPAGGRYEHPGLGALGTQQPP-----VAVPG--------GGGGPAAVPEFNNY 175
PP + P G E +G G PP +PG G GPA +P
Sbjct: 993 PGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLP----- 1047
Query: 176 YGSAAPAS--GGPGGRAGP----CFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSH 229
G P G PG R P G + PG AG+PG P +
Sbjct: 1048 -GKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPG-------PPGPAGSPGERGPAGAAG 1099
Query: 230 E-GYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAA 288
G P PG P G G G G G G G G G A
Sbjct: 1100 PIGIPGR-----PGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGE 1154
Query: 289 AAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMG-PGGGGAASLSKAAAGSAAGGFQRF 347
G G G GS G P G +G PG GA G +
Sbjct: 1155 DGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGD 1214
Query: 348 AGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407
G P P Q L P P + G + PP P P+ + A GA G
Sbjct: 1215 EGPRGFPGPPGPVGLQGLPGP-PGEKGETGDVGQMG-----PPGPPGPRGPSGAPGAD-G 1267
Query: 408 GQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKR 467
Q G+G +P + A PG PG +G P P
Sbjct: 1268 PQGPPGGIG------------NPGAVGEKGEPGEAGEPGLPG------EGGPPGPK---- 1305
Query: 468 PQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPP--- 524
+ ++ P G+ GPPGP+ P G G G+ + +P PP
Sbjct: 1306 ----------GERGEKGESGPSGAAGPPGPKGPP-GDDG-PKGSPGPVGFPGDPGPPGEP 1353
Query: 525 -QYGQQGVSGYCQQGQQPYYSQQPQP-----PHLPPQAQYLPSQSQQRYQPQQDMSQEGY 578
GQ G G +P + P P P PP + P + + + ++
Sbjct: 1354 GPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEA 1413
Query: 579 GTRSQP----PL----APGKPNHEDLNLI-----QQERPSS--------------LPDLS 611
G P P+ APGKP + L I +Q P S LP L
Sbjct: 1414 GLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLK 1473
Query: 612 GSIDDLPTGTEAT--LSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGP--SPS 667
G D P G + L + G +GD+ P S + P GP P
Sbjct: 1474 G--DSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPG 1531
Query: 668 PVG-----SPVGSNQSRSGPISPASIPGSQMPPQPPGSQSE 703
P G P G+ S SGP P G PP PPG E
Sbjct: 1532 PPGLPGPPGPKGAKGS-SGPTGPKGEAGHPGPPGPPGPPGE 1571
Score = 70.5 bits (171), Expect = 2e-11
Identities = 143/569 (25%), Positives = 180/569 (31%), Gaps = 74/569 (13%)
Query: 76 ISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMG 135
+ N G G A PG E+ G A G+ P GPP P E AP + G
Sbjct: 1073 LKGNEGPPGPPGPAGSPG---ERGPAGAAGPIGIPGRPGPQGPP---GPAGEKGAPGEKG 1126
Query: 136 E--PAGGRYEHPGL-GALGTQQP--PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRA 190
PAG GL G +G P PV PG G + E GP G
Sbjct: 1127 PQGPAG----RDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPT 1182
Query: 191 GPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPL----QNSHEGYPNSQCNHYPGYSRP 246
GP G PG + A G PG Q EG P +PG P
Sbjct: 1183 GP----QGPIGQPG-------PSGADGEPGPRGQQGLFGQKGDEG-PRG----FPGPPGP 1226
Query: 247 GAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAG 306
G G G G +G G G G G + A A GG G G G
Sbjct: 1227 VGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGE 1286
Query: 307 YGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLT 366
G P G G GP G +G+A + + P G
Sbjct: 1287 PGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKG---------- 1336
Query: 367 SPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAG-MGLGKDMGAQY 425
SP P+ +P P P P Q GQ + G G G
Sbjct: 1337 SPGPV------GFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPG 1390
Query: 426 AAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPM-VMKRPQLYGMGSNPHSQPQQS 484
P A + R + G G + P+ P +P G+ P +Q
Sbjct: 1391 KRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQG 1450
Query: 485 SPYPGGSYGPPGPQRYP--IGIQGRT--------PGAMAGMQYPQQQMPPQYGQQGVSGY 534
P G GPPGP P G++G + PG + + P +Q + G +G+ G
Sbjct: 1451 LPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQ--GEKGDRGLPG- 1507
Query: 535 CQQGQQPYYSQQ----PQPPHLPPQAQYLPSQSQQRYQPQQD--MSQEGYGTRSQPPLAP 588
QG +Q P P PP LP + +G PP P
Sbjct: 1508 -PQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPP 1566
Query: 589 GKPNHEDLNL-IQQERPSSLPDLSGSIDD 616
G P L IQ R D S +DD
Sbjct: 1567 GPPGEVIQPLPIQASRTRRNIDASQLLDD 1595
Score = 49.3 bits (116), Expect = 4e-05
Identities = 131/612 (21%), Positives = 187/612 (30%), Gaps = 125/612 (20%)
Query: 379 YPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLG-------------KDMGAQY 425
Y E+ SP P PQSQ + G G G +D+G +
Sbjct: 236 YCEHYSPDCDTAVPDTPQSQDPNP-----DEYYTEGDGEGETYYYEYPYYEDPEDLGKEP 290
Query: 426 AAASPAWAAAQQRSH------PAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSN--- 476
+ AA++ + P + P P G D G+G
Sbjct: 291 TPSKKPVEAAKETTEVPEELTPTPTEAAPMPETSEGAGKEED---------VGIGDYDYV 341
Query: 477 PHSQPQQSSPYPGGSYGP----PGPQRYPIGIQGRTPGAMAGMQYPQQQMPP-------- 524
P SPY +YG P P G P + A PP
Sbjct: 342 PSEDYYTPSPYDDLTYGEGEENPDQPTDP-GAGAEIPTSTADTSNSSNPAPPPGEGADDL 400
Query: 525 --QYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQ----PQQDMSQEGY 578
++ ++ + + PYY P + P +P+ Y+ P+ + Q+G
Sbjct: 401 EGEFTEETIRNLDENYYDPYYDPTSSPSEIGPG---MPANQDTIYEGIGGPRGEKGQKGE 457
Query: 579 GTRSQP-PLAPGKPNHE----------------DLNLIQQERPSSLPDLSGSIDDL--PT 619
+P L G P E + + P P L G+ D L P
Sbjct: 458 PAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGA-DGLPGPP 516
Query: 620 GTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSI--PGGP-----SPSPVGSP 672
GT L G S+G + +S ++ P GP P PVG P
Sbjct: 517 GTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPP 576
Query: 673 -VGSNQSRSGPISPASIPGSQMPPQP---PGSQSESSSHPAL---SQSPMPQERGFMAGT 725
G + G + P G Q PP P PG + + S A Q+ +RGF
Sbjct: 577 GSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLA 636
Query: 726 QRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQ--MSQYGPQG--N 781
+ G GPS P P PG G G GP+ + GP+G
Sbjct: 637 GLPGEKGHRG--DPGPSGPPGP-PGDDGERG--------DDGEVGPRGLPGEPGPRGLLG 685
Query: 782 YSRPPAYSGVPSAS--YSGPGPGMGISANNQ---------MHGQGPSQPCGAV------- 823
PP G P + PGP + + QG P GA+
Sbjct: 686 PKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKG 745
Query: 824 PLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAA 883
PLG+ GM P QG PG P+ + + A +
Sbjct: 746 PLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKG 805
Query: 884 NSAQSRQGSFPG 895
+ + FPG
Sbjct: 806 TKGEKGEDGFPG 817
Score = 32.3 bits (72), Expect = 5.3
Identities = 47/213 (22%), Positives = 69/213 (32%), Gaps = 55/213 (25%)
Query: 1152 GDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGG 1211
G+T Q K PP P + GPQ P TG G PP P P Q P G
Sbjct: 982 GETGFQGKTGPPGPPG---VVGPQGP--TGETGPMGERGHPGPPGP---PGEQGLPGLAG 1033
Query: 1212 RSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVP 1271
+ T D + P ++ + +P +G + + N+ P P
Sbjct: 1034 KEGTKG------DPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGP-------P 1080
Query: 1272 GSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQ 1331
G P + G+ + P+GA +G+ PG+
Sbjct: 1081 GPPGPAGSPGE-----------RGPAGAAGPIGI-----------------------PGR 1106
Query: 1332 GPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGP 1364
P G P G + + P DG+ GP
Sbjct: 1107 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGP 1139
>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
Length = 1669
Score = 98.2 bits (243), Expect = 8e-20
Identities = 252/1040 (24%), Positives = 329/1040 (31%), Gaps = 205/1040 (19%)
Query: 111 GQADPPGPP-------LLSKPGDED--DAPPKMGEPAGGRYEHPGLGALGTQQPP-VAVP 160
G+A PPGPP L + G+ P GEP G PGL G PP + VP
Sbjct: 323 GEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEP--GPKGFPGLP--GQPGPPGLPVP 378
Query: 161 GGGGGPAAVPEFNN-----YYGSAAPASGGPGGRAGPCFDQHGGQQSPGM-GMMHSASAA 214
G G P E + G++ P G G GP G PG G +
Sbjct: 379 GQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGP----PGSPGPPGQPGYTNGIVEC 434
Query: 215 AAGAPGSMDPL----------QNSHEGYPNSQC--------NHYPGYSRPGAGGGGGGGG 256
G PG P + +G C PG P G G
Sbjct: 435 QPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQP 494
Query: 257 GGGGGSGGGGGGGGAGAGGAGA--GAVAAAAAAAAAAA--------GGGGGGGYGGSSAG 306
G G G G G AG G G + A G G G+ G
Sbjct: 495 GAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGM 554
Query: 307 YGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAG-GFQRFAGQNQHPS--GATPTLNQ 363
G SP + G + GP G + K G G GF G P G P
Sbjct: 555 TGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPA--- 611
Query: 364 LLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGA-AAGGQQAAAGM-GLGKDM 421
P+ +P P P +P G A G + G G D
Sbjct: 612 -----GPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDR 666
Query: 422 GAQYAAASPAWAAAQQR-SHPAMS-PGTPGPTMGRSQGSPMD---PMVMKRPQLYGMGSN 476
G P + P + PG PGP G P D P RP G+ N
Sbjct: 667 GFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPK--GVDGLPGDMGPPGTPGRPGFNGLPGN 724
Query: 477 PHSQPQQSSPYPG--GSYGPPGPQRYP--------IGIQGRTPGAMAGMQYPQQQ----- 521
P Q Q+ P G G G PG P IG+ G PG + P Q
Sbjct: 725 PGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPG-VPGEHGAIGPPGLQGIRGE 783
Query: 522 -----MPPQYGQQGVSGYCQQGQQ-PYYSQQPQ----PPHLPPQAQYLPSQSQQRYQPQQ 571
+P G GV G G + P Q P PP + + + P+
Sbjct: 784 PGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKG 843
Query: 572 DMSQEGY-GTRSQPPLAPGKPNHEDLNLIQQERPS--SLPDLSGSIDDLPTGTEATLSSA 628
D +G G Q L PG P QQ P P G + + T +
Sbjct: 844 DKGAQGLPGITGQSGL-PGLPG-------QQGAPGIPGFPGSKGEMGVMGTPGQPGSPGP 895
Query: 629 VSASGSTSSQGDQSNPAQSPFSPHASPHLSS------IPGGPSPSP---VGSPVGS--NQ 677
V A G +GD P S P P L +PG P +GS G +Q
Sbjct: 896 VGAPGLPGEKGDHGFPGSS--GPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQ 953
Query: 678 SRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQ 737
G I P GS+ P PG + Q P P+ ++GT P + GP+
Sbjct: 954 GEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQ-PGPKGDPGISGTPGAPGLP--GPK 1010
Query: 738 QTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYS 797
+ M +PG + GI GPQG+ P +
Sbjct: 1011 GSVGGMGLPGTPGEKGVPGIP------------------GPQGSPGLPGDKGAKGEKGQA 1052
Query: 798 GPGPGMGISANNQMHG-QG----PSQPCGAVPLGRMPSAGMQNRP----FPGNMSSMTPS 848
GP PG+GI G QG P P G + GM P PG++ P
Sbjct: 1053 GP-PGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGY--PG 1109
Query: 849 SPGMSQQGG----PGM-------------GPPMPT--VNRKAQEAAAAVMQAAANSAQSR 889
SPG+ + G PG+ G P PT +K + + + +A +
Sbjct: 1110 SPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEP- 1168
Query: 890 QGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPG 949
PG G + + S P + +P + S + G
Sbjct: 1169 --GLPGRGFPGFPGAKG-------DKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQG 1219
Query: 950 ESKLPLPLKADGKEEGTPQPESKS-KDSYSSQGISQPPTPGNLPVPSPMSPSSA-SISSF 1007
+ LP G+P ++ K QG QP PG +P PM P I
Sbjct: 1220 QPGLP----------GSPGHATEGPKGDRGPQG--QPGLPG---LPGPMGPPGLPGIDGV 1264
Query: 1008 HGDESDSISSPGWPKTPSSP 1027
GD+ + PGWP P P
Sbjct: 1265 KGDKGN----PGWPGAPGVP 1280
Score = 86.7 bits (213), Expect = 2e-16
Identities = 216/917 (23%), Positives = 279/917 (30%), Gaps = 149/917 (16%)
Query: 111 GQADPPGPPLLSKPGDEDDAPPKMGEP----AGGRYEHPGLGALGTQQPPVAVPG----- 161
G P GPP E P G A G +PGL + Q P PG
Sbjct: 67 GPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCN 126
Query: 162 ---GGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGA 218
G GP P + G+ P G PG + P G GM+ G
Sbjct: 127 GTKGERGPLGPPGLPGFAGNPGPP-GLPGMKGDP-----GEILGHVPGMLLKGERGFPGI 180
Query: 219 PGSMDPLQNSHEGYPNSQCN-HYPGYSRPGAGGGGGGGGGGGGGSG---GGGGGGGAGAG 274
PG+ P G P Q PG++ P G G G G G G G G
Sbjct: 181 PGTPGP-----PGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQG 235
Query: 275 GAGAGAVAAAAA-------AAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGG 327
+G V A A G G G+ G G G P + G G G
Sbjct: 236 VSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMP-GVGEKGEPGKPGPRGKPGKDGD 294
Query: 328 GAASLSKAAAGSAA--GGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSP 385
S G G R Q + P ++ P+ YP P
Sbjct: 295 KGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGP 354
Query: 386 SAPPPPPSQP--QSQAAAAGAAAGGQQAAAGM----GLGKDMGAQYAAASPAWAAAQQRS 439
P P P Q G GQ A G G D G + P +
Sbjct: 355 RGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFP-GTSLPGPSGRDGLP 413
Query: 440 HPAMSPGTPGP---TMGRSQGSPMDPMVMKRPQLYG-------MGSNPHSQPQQSSPYPG 489
P SPG PG T G + P P P + G +G
Sbjct: 414 GPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDID 473
Query: 490 GSYGPPGPQRYP--IGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQP 547
G GPPGPQ P IG G+ PGA + +P + G GV G QG Q
Sbjct: 474 GYRGPPGPQGPPGEIGFPGQ-PGAKG-----DRGLPGRDGVAGVPG--PQGTPGLIGQ-- 523
Query: 548 QPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPL-----APGKPNHEDLNLIQQE 602
P A+ P + + + D G+ QP + +PG+ H
Sbjct: 524 ------PGAKGEPGEFYFDLRLKGDKGDPGFP--GQPGMTGRAGSPGRDGHP-------- 567
Query: 603 RPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPG 662
LP GS + E V GS G P P P + PG
Sbjct: 568 ---GLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPG 624
Query: 663 GPS----PSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQE 718
GP P P G P G GP +PGS P PG Q + + +P E
Sbjct: 625 GPGSPGLPGPKGEP-GKIVPLPGPPGAEGLPGS---PGFPGPQGDRGFPGTPGRPGLPGE 680
Query: 719 RGFMAGTQRNPQMAQYGPQQTGP--------SMSPHPSPGGQMHAGISSFQQSNSSGTYG 770
+G + P + GP GP M P +PG G+
Sbjct: 681 KGAVG----QPGIGFPGP--PGPKGVDGLPGDMGPPGTPGRPGFNGLP------------ 722
Query: 771 PQMSQYGPQGNYSRP----PAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLG 826
G QG P P G+P PG+ + + P P +G
Sbjct: 723 ---GNPGVQGQKGEPGVGLPGLKGLPGL------PGIPGTPGEKGSIGVPGVPGEHGAIG 773
Query: 827 RMPSAGMQNRPFPGNMSSMTPSSPG-MSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANS 885
G++ P P P PG + G PG+GPP Q
Sbjct: 774 PPGLQGIRGEPGP-------PGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKG 826
Query: 886 AQSRQGSFPGMNQSGLMASSSPYSQP-MNNSSSLMNTQAPPYSMAPAMVNSSAASVGLAD 944
+ G FPG++ G P + S L P AP + + +
Sbjct: 827 EKGFPG-FPGLDMPGPKGDKGAQGLPGITGQSGLPG--LPGQQGAPGIPGFPGSKGEMGV 883
Query: 945 MMSPGESKLPLPLKADG 961
M +PG+ P P+ A G
Sbjct: 884 MGTPGQPGSPGPVGAPG 900
Score = 80.1 bits (196), Expect = 2e-14
Identities = 248/1027 (24%), Positives = 318/1027 (30%), Gaps = 182/1027 (17%)
Query: 73 QHPISNNNSLGGAGGGAPQPGPDMEQPQHG----GAK-DSAAGGQADPPGPPLLSKPGDE 127
Q P+ G G P PGP E+ Q G G K D G + PPG P ++ ++
Sbjct: 193 QGPVGPPGFTGPPGPPGP-PGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEK 251
Query: 128 DDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPG 187
D K + G G+ +G + P G GP P + G G PG
Sbjct: 252 GDFATKGEKGQKGEPGFQGMPGVGEKGEP-----GKPGPRGKPGKDGDKGE----KGSPG 302
Query: 188 GRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPG---SMDPL-QNSHEGYPNSQCNHYPGY 243
P + G+Q P A G PG PL + GYP + PG
Sbjct: 303 FPGEPGYPGLIGRQGP---QGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGT-----PG- 353
Query: 244 SRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGS 303
R G G G G G G G AGA G G G G+ G+
Sbjct: 354 PRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPG------------FPGERGEKGDRGFPGT 401
Query: 304 SAGYGVLSSPRQQGG--GMMMGPGGGGAASLSKAAAGSAAG--GFQRFAGQNQHPSGATP 359
S L P + G G PG G + G G Q G P
Sbjct: 402 S-----LPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGE 456
Query: 360 TLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQ---PQSQAAAAGAAAGGQQAAAGM- 415
+ S ++ G Y P P PP + P A G+ AG+
Sbjct: 457 IGEKGQKGESCLICDIDG----YRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVP 512
Query: 416 ---GLGKDMGAQYAAASPAWAAAQQR-SHPAMSPGTPG-PTMGRSQGSPMDPMVMKRPQL 470
G +G A P R PG PG P M GSP P L
Sbjct: 513 GPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRD---GHPGL 569
Query: 471 YGMGSNPHS-------QPQQSSPYPG--GSYGPPGPQRY----PIGIQGRTPGAMAGMQY 517
G +P S P +PG G GPPGP Y PIG +G
Sbjct: 570 PGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKG----------- 618
Query: 518 PQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEG 577
Q P G G+ G +G+ P PP A+ LP S PQ D G
Sbjct: 619 -QAGFPGGPGSPGLPG--PKGEPGKIVPLPG----PPGAEGLPG-SPGFPGPQGDRGFPG 670
Query: 578 YGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSS 637
R P G + P + L G + P GT G+
Sbjct: 671 TPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMG--PPGTPGR-PGFNGLPGNPGV 727
Query: 638 QGDQSNPAQSPFSPHASPHLSSIPGGP-SPSPVGSPVGSNQSRSGPISPASIPGSQMPPQ 696
QG + P P L IPG P +G P G I P + G + P
Sbjct: 728 QGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVP--GVPGEHGAIGPPGLQGIRGEPG 785
Query: 697 PPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAG 756
PPG S P G R P Q P +GP PG + G
Sbjct: 786 PPGLPGSVGS---------PGVPGIGPPGARGPPGGQGPPGLSGP-------PGIKGEKG 829
Query: 757 ISSFQQSNSSGTYGPQMSQYGP----QGNYSRPPAYSGVPS-ASYSGPGPGMGISANNQM 811
F + G G + +Q P Q P G P + G MG+
Sbjct: 830 FPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGT--- 886
Query: 812 HGQGPSQPCGAVPLGRMPSAGMQ-NRPFPGNMSSMTPSSPGMSQQGG----PGMGPPMPT 866
P QP P+G G + + FPG SS PG+ G PG M
Sbjct: 887 ----PGQPGSPGPVGAPGLPGEKGDHGFPG--SSGPRGDPGLKGDKGDVGLPGKPGSMDK 940
Query: 867 VN------RKAQEAAAAVMQAAANSAQSRQGSFPGM----NQSGLMASSSPYSQPMNNSS 916
V+ +K + + PG+ Q+G P P
Sbjct: 941 VDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDP----- 995
Query: 917 SLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESK---- 972
+ T P P S +GL +PGE +P G P P+
Sbjct: 996 GISGTPGAPGLPGP---KGSVGGMGLPG--TPGEKGVP----------GIPGPQGSPGLP 1040
Query: 973 -SKDSYSSQGISQPPTPGNLPVPSPM-SPSSASISSFHGD-----ESDSISSPGWPKTPS 1025
K + +G + PP G +P I+ F G E SI PG P +P
Sbjct: 1041 GDKGAKGEKGQAGPPGIG---IPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPG 1097
Query: 1026 SPKSSSS 1032
S S
Sbjct: 1098 LKGSPGS 1104
Score = 78.2 bits (191), Expect = 8e-14
Identities = 171/689 (24%), Positives = 220/689 (31%), Gaps = 71/689 (10%)
Query: 82 LGGAGGGAPQPG---PDMEQPQHGGAKDSAAG-----GQADPPGPPLLSKPGDEDDAPPK 133
L G+ G PG P P G +G G+ PG P L PG + D K
Sbjct: 789 LPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGD---K 845
Query: 134 MGEPAGGRYEHPGLGALGTQQPPVAVPG--GGGGPAAVPEFNNYYGSAAP--ASGGPGGR 189
+ G GL L QQ +PG G G V GS P A G PG +
Sbjct: 846 GAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEK 905
Query: 190 AGPCFDQHGGQQS-PGMGMMHSASAAAAGAPGSMDPLQ-NSHEGYPNSQCNHYPGYSRPG 247
F G + PG+ G PGSMD + S +G Q G P
Sbjct: 906 GDHGFPGSSGPRGDPGL-KGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEK--GQIGPI 962
Query: 248 AGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307
G G G G G G G G G + G G G GS G
Sbjct: 963 GEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDP------GISGTPGAPGLPGPKGSVGGM 1016
Query: 308 GVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTS 367
G+ +P ++G + GP G K A G GQ P P L
Sbjct: 1017 GLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGE--------KGQAGPPGIGIPGLRG--EK 1066
Query: 368 PSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAA 427
+ + GS P P P S + G + G+ G +
Sbjct: 1067 GDQGIAGFPGS-PGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGL-----PGEKGDK 1120
Query: 428 ASPAWAAAQQRSHPAMSPGTPGPTMGRSQ-GSPMDPMVMKRPQLYGMGSNPHSQPQQSSP 486
P A PGTPGPT Q G P + P G P +
Sbjct: 1121 GLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGI---PGSAGEKGEPGLPGRGFPG 1177
Query: 487 YPG--GSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYS 544
+PG G G G +P G+ G +PG + G + Q M P G QG G G + +
Sbjct: 1178 FPGAKGDKGSKGEVGFP-GLAG-SPG-IPGSKGEQGFMGPP-GPQGQPGL--PGSPGHAT 1231
Query: 545 QQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQP--PLAPGKPNHE-DLNLIQQ 601
+ P+ P LP P G + P P APG P + D
Sbjct: 1232 EGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGM 1291
Query: 602 ERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIP 661
P ++GS D+ G +GDQ + P +P
Sbjct: 1292 PGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGD--------QGVPGAKGLP 1343
Query: 662 GGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGF 721
G P P + GP P + G Q P P G Q + +P GF
Sbjct: 1344 GPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIP---GF 1400
Query: 722 MAGTQRNPQMAQYGPQQTGPSMSPHPSPG 750
+ +M GP TGP P P PG
Sbjct: 1401 DGAPGQKGEMGPAGP--TGPRGFPGP-PG 1426
Score = 76.6 bits (187), Expect = 2e-13
Identities = 220/903 (24%), Positives = 278/903 (30%), Gaps = 173/903 (19%)
Query: 82 LGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGR 141
L G G G E+ GG + G PPGPP G D + G P G
Sbjct: 569 LPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGD-KGQAGFPGGP- 626
Query: 142 YEHPGL-GALGTQQPPVAVPG--GGGGPAAVPEFNNYYGSAA-PASGGPGGRAGPCFDQH 197
PGL G G V +PG G G P F G P + G G G +
Sbjct: 627 -GSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPG----EK 681
Query: 198 GGQQSPGMGMMHSASAAAA-GAPGSMDPLQ-------NSHEGYPNSQCNH-YPGYSRPGA 248
G PG+G G PG M P N G P Q PG PG
Sbjct: 682 GAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGL 741
Query: 249 GG--------GGGGGGGGGGGSGGGGGGGGAGAGG--------------AGAGAVAAAAA 286
G G G G G G G G G G G+
Sbjct: 742 KGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGI 801
Query: 287 AAAAAAGGGGGGGYGGSSA-----------GYGVLSSPRQQGGGMMMG-PGGGGAASLSK 334
A G GG G G S G+ L P +G G PG G + L
Sbjct: 802 GPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPG 861
Query: 335 AAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPM------MRSYGGSYPEYSSPSAP 388
A G F G ++ G T Q SP P+ +P S P
Sbjct: 862 LPGQQGAPGIPGFPG-SKGEMGVMGTPGQ-PGSPGPVGAPGLPGEKGDHGFPGSSGPRGD 919
Query: 389 P---------PPPSQPQSQAAAAGAAAGGQQAAAG-MGLGKDMGAQYAAASPAWAAAQQR 438
P P +P S + GQ+ G G +G + + P +
Sbjct: 920 PGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGK 979
Query: 439 SHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQ 498
A PG PGP +G P P L G + +P G G PGPQ
Sbjct: 980 DGQAGQPGQPGP-----KGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQ 1034
Query: 499 RYPIGIQGRTPGAMAGMQYPQQQMPP---------QYGQQGVSGY----CQQGQQPYYS- 544
P PG Q PP + G QG++G+ ++G++
Sbjct: 1035 GSP-----GLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGI 1089
Query: 545 -QQPQPPHLP--------PQAQYLPSQSQQRYQPQQDMSQEGYGTRSQP----PLAP--- 588
P P L P + LP + + P D G P P P
Sbjct: 1090 PGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQ 1149
Query: 589 -GKPNHEDLNLIQQERPS------SLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQ 641
G+P + + E+ P G+ D + E + G S+G+Q
Sbjct: 1150 KGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQ 1209
Query: 642 SNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPG-- 699
P P P L PG + P G GP +PG P PPG
Sbjct: 1210 G--FMGPPGPQGQPGLPGSPGHATEGPKGD--------RGPQGQPGLPGLPGPMGPPGLP 1259
Query: 700 ---SQSESSSHPALSQSP-MPQERGFMAGTQRNPQMAQYGPQQTGP--SMSPHPSPGGQM 753
+P +P +P +G G Q P + P TG M P PG Q
Sbjct: 1260 GIDGVKGDKGNPGWPGAPGVPGPKG-DPGFQGMPGIGG-SPGITGSKGDMGPPGVPGFQG 1317
Query: 754 HAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHG 813
G+ Q G G Q G QG P G+P PGP I +
Sbjct: 1318 PKGLPGLQ-----GIKGDQ----GDQG----VPGAKGLPGPP-GPPGPYDIIKGEPGL-- 1361
Query: 814 QGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMT-----PSSPGM-SQQGGPG----MGPP 863
GP P G G+Q P P +T P PG+ G PG MGP
Sbjct: 1362 PGPEGPPGL--------KGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPA 1413
Query: 864 MPT 866
PT
Sbjct: 1414 GPT 1416
Score = 55.5 bits (132), Expect = 6e-07
Identities = 158/677 (23%), Positives = 204/677 (30%), Gaps = 144/677 (21%)
Query: 276 AGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKA 335
A G A + G G G G GV+ P QG GP G +
Sbjct: 26 AAKGGCAGSGCGKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPG 85
Query: 336 AAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGS--YPEYSSPSAPPPPPS 393
G+ + P GA+ Y G+ P PP PP
Sbjct: 86 LPGTKG---------TRGPPGAS---------------GYPGNPGLPGIPGQDGPPGPPG 121
Query: 394 QPQSQAAAAGAAAGGQQAAAGM----------GLGKDMGAQYAAASPAWAAAQQRSHPAM 443
P G G G+ D G + P +R P +
Sbjct: 122 IPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPG-EILGHVPGMLLKGERGFPGI 180
Query: 444 SPGTPGPT-MGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPG-----GSYGPPGP 497
PGTPGP + QG P P G P + Q + G G G GP
Sbjct: 181 -PGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGP 239
Query: 498 QRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQP-------- 549
P Q + G A Q+ P G QG+ G ++G+ + +P
Sbjct: 240 PGVPGQAQVQEKGDFATKGEKGQKGEP--GFQGMPGVGEKGEPGKPGPRGKPGKDGDKGE 297
Query: 550 ---PHLPPQAQYLPSQSQQRYQPQQDMSQEG--------YGTRSQPPLA-------PGKP 591
P P + Y +Q PQ + + G GT PL PG P
Sbjct: 298 KGSPGFPGEPGYPGLIGRQ--GPQGEKGEAGPPGPPGIVIGT---GPLGEKGERGYPGTP 352
Query: 592 NHEDLNLIQQERPSSLPDLSG--SIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPF 649
+ P P L G LP +A A G +GD+ P S
Sbjct: 353 GPRG-----EPGPKGFPGLPGQPGPPGLPVPGQA---GAPGFPGERGEKGDRGFPGTSLP 404
Query: 650 SPHASPHLSSIPGGPSPSPVGSPVGSN---QSRSGPISPASIPGSQMPPQPPGSQS---- 702
P L PG SP P G P +N + + GP PG Q PP PG
Sbjct: 405 GPSGRDGLPGPPG--SPGPPGQPGYTNGIVECQPGP------PGDQGPPGIPGQPGFIGE 456
Query: 703 ----------------ESSSHPALSQSP--------MPQERGFMAGTQRNPQMAQYGPQQ 738
+ P Q P P +G R+ GPQ
Sbjct: 457 IGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQG 516
Query: 739 TGPSMSPHPSPGGQMHAGISSFQQSNSSGTYG----PQMS-QYGPQGNYSRP--PAYSGV 791
T P + P G+ + G G P M+ + G G P P G
Sbjct: 517 T-PGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGS 575
Query: 792 P-SASYSGP-GPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSS 849
P S G GP G+ GP P G P G + G FPG P S
Sbjct: 576 PGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAG--FPGG-----PGS 628
Query: 850 PGM-SQQGGPGMGPPMP 865
PG+ +G PG P+P
Sbjct: 629 PGLPGPKGEPGKIVPLP 645
Score = 48.1 bits (113), Expect = 9e-05
Identities = 125/550 (22%), Positives = 174/550 (31%), Gaps = 94/550 (17%)
Query: 525 QYGQQGVSGYCQQGQQPYYSQQ-PQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQ 583
Q G++G+ G QG + Q P+ P PP Q +P ++ GTR
Sbjct: 47 QKGERGLPGL--QGVIGFPGMQGPEGPQGPP------GQKGDTGEPGLPGTK---GTRG- 94
Query: 584 PPLAPGKPNHEDLNLIQQER----PSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQG 639
PP A G P + L I + P +P +G+ + L G G
Sbjct: 95 PPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPG 154
Query: 640 DQSNPAQSPFSPHASPHL----SSIPGGP-SPSPVGSPVGSNQSRSGPISPASIPGSQMP 694
+ +P + H L PG P +P P G P GP+ P G P
Sbjct: 155 MKGDPGE--ILGHVPGMLLKGERGFPGIPGTPGPPGLP-----GLQGPVGPPGFTGPPGP 207
Query: 695 PQPPGSQSESSSHPALSQSPMPQ--ERGFMA--GTQRNPQMAQYGPQQTGPSMSPHPSPG 750
P PPG E Q P ++G G Q+ + G T PG
Sbjct: 208 PGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPG 267
Query: 751 GQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRP-----PAYSGVPSASYSGPGPGMGI 805
Q G+ + G G + + G +G P P Y G+ GP G
Sbjct: 268 FQGMPGVGEKGEPGKPGPRG-KPGKDGDKGEKGSPGFPGEPGYPGL--IGRQGPQGEKGE 324
Query: 806 SANNQMHGQGPSQPCGAV----PLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMG 861
+ GP P G V PLG G P P PG+ Q GP G
Sbjct: 325 A--------GPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPG-PKGFPGLPGQPGP-PG 374
Query: 862 PPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLM---------ASSSPYSQPM 912
P+P A + FPG + G S P QP
Sbjct: 375 LPVP--------GQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPG 426
Query: 913 NNSSSLMNTQAPPYSMAPAMVNSSAASVG-LADMMSPGESKL----------PLPLKADG 961
+ + PP P + +G + + GES L P P G
Sbjct: 427 YTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPG 486
Query: 962 KEEGTPQPESKSKDSYSSQ-GISQPPTPGNLPVPSPMSPSSASISSFH------GDESDS 1014
+ QP +K + G++ P P P + F+ GD+ D
Sbjct: 487 EIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGD- 545
Query: 1015 ISSPGWPKTP 1024
PG+P P
Sbjct: 546 ---PGFPGQP 552
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 97.4 bits (241), Expect = 1e-19
Identities = 130/490 (26%), Positives = 157/490 (32%), Gaps = 129/490 (26%)
Query: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY 300
P +P G GGGGGG GGG G GGGGGG G G + GGGG G
Sbjct: 57 PILDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGG----------------SFGGGGPPGL 100
Query: 301 GG-SSAGYGVLSSPRQQ-----GGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHP 354
GG AG L S + G + P GG + S + S G F H
Sbjct: 101 GGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFP--VPSPGHR 158
Query: 355 SGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAG 414
SG + P P + GS P+ S PPP PS P+
Sbjct: 159 SGPPEPQRNRMPPPRPDV----GSKPD----SIPPPVPSTPR------------------ 192
Query: 415 MGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMG 474
Q H SP PG S G P R G G
Sbjct: 193 -------------------PIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGG 233
Query: 475 SNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGY 534
S S SSP+ PP P R A P PP
Sbjct: 234 SIRQSPLSSSSPFSNRPPLPPTPSR-------------ALDDKPPPPPPP---------- 270
Query: 535 CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHE 594
G +P ++ PP PPQ P S P+ S + PP P +P
Sbjct: 271 --VGNRPSIHREAVPPP-PPQNNKPPVPS----TPRPSASSQA----PPPPPPPSRPG-- 317
Query: 595 DLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHAS 654
P LP S D+ P + LS +S+S +S P P S
Sbjct: 318 ---------PPPLPPSSSGNDETPRLPQRNLS--LSSSTPPLPSPGRSGPLPPPPSERPP 366
Query: 655 PHLSSIPGGPSPSPVGSPVGSN-------------QSRSGPISPASIPGSQMPPQPPGSQ 701
P + PG P P PV N SRSG SP S P +PP P +
Sbjct: 367 PPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAG 426
Query: 702 SESSSHPALS 711
+ P+ S
Sbjct: 427 APPPPPPSTS 436
Score = 57.8 bits (138), Expect = 1e-07
Identities = 100/451 (22%), Positives = 152/451 (33%), Gaps = 49/451 (10%)
Query: 447 TPGPTMGRSQGSPMDPM---VMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIG 503
T PT+ +++ + + + + K +L +N S P P G+ G G G
Sbjct: 20 TEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDKPKGAGAGGGGGGFGGGGG 79
Query: 504 IQGRTPGAMAGMQYPQQQMPPQYG---QQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLP 560
G G G PP G Q G+ + S +PP LPP +
Sbjct: 80 FGGGGGGGGGGSFGGGG--PPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGR--- 134
Query: 561 SQSQQRYQPQQDMSQ---EGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDL 617
S S + + P + G RS PP +P + P PD+ D +
Sbjct: 135 STSAKPFSPPSGPGRFPVPSPGHRSGPP----EPQRNRM-------PPPRPDVGSKPDSI 183
Query: 618 PTGTEAT---LSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPS--PSPVGSP 672
P +T + S+ GS G P+ P P + + GG S SP+ S
Sbjct: 184 PPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSS 243
Query: 673 VGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMA 732
+ P +P+ + PP PP + S H P PQ + P +
Sbjct: 244 SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSAS 303
Query: 733 QYGPQQTGPSMSPHPSPGGQMHAGISSF----QQSNSSGTYGPQMSQYGPQGNYSRPPAY 788
P P P P P +G Q++ S + P + G G PP+
Sbjct: 304 SQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE 363
Query: 789 SGVPSA----SYSGP-GPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMS 843
P SGP P +S N P+ P ++PS + P G
Sbjct: 364 RPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATP-------QLPSRSGVDSPRSGPRP 416
Query: 844 SMTPSSPGMSQQGGPGMGPPMPTVNRKAQEA 874
+ P P G P PP ++ Q++
Sbjct: 417 PLPPDRP---SAGAPPPPPPSTSIRNGFQDS 444
Score = 51.6 bits (122), Expect = 9e-06
Identities = 74/308 (24%), Positives = 105/308 (34%), Gaps = 80/308 (25%)
Query: 747 PSPGGQMHAGI----SSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPG 802
P GG AG+ S+ + N SG P + G + ++P + P + P PG
Sbjct: 98 PGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGR-FPVPSPG 156
Query: 803 MGISANNQMHGQGPSQP-----------CGAVPLGRMPSAGMQNRPF---PGNMSSMTPS 848
H GP +P G+ P P RP P N S P
Sbjct: 157 ---------HRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGS--PP 205
Query: 849 SPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQ--SRQGSFPGMNQSGLMASSS 906
PG +Q PG PP NR ++ Q+ +S+ S + P L
Sbjct: 206 VPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP 265
Query: 907 PYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGT 966
P P+ N S+ PP P +K P+P T
Sbjct: 266 PPPPPVGNRPSIHREAVPP--------------------PPPQNNKPPVP--------ST 297
Query: 967 PQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSS 1026
P+P + S+ PP P + P P P+ PSS+ DE+ P+ P
Sbjct: 298 PRPSASSQ-------APPPPPPPSRPGPPPLPPSSSG-----NDET--------PRLPQR 337
Query: 1027 PKSSSSTT 1034
S SS+T
Sbjct: 338 NLSLSSST 345
Score = 47.8 bits (112), Expect = 1e-04
Identities = 82/300 (27%), Positives = 106/300 (35%), Gaps = 66/300 (22%)
Query: 1329 PGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEG---DMYNMQYSSQ---- 1381
P GP P GH+ G P +P R PP + G D S
Sbjct: 143 PPSGPGRFPVPSPGHRSG--PPEPQRNRM------PPPRPDVGSKPDSIPPPVPSTPRPI 194
Query: 1382 QQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSS--SS 1439
Q +N+ G R+P G P P+ R G GG ++ S SS
Sbjct: 195 QSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALG------------GGSIRQSPLSS 242
Query: 1440 EGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVS 1499
P N R +P P +R P PP G NR I+ E+ P
Sbjct: 243 SSPFSN----RPPLP-PTPSRALDDKPPPPPPPVG-NRPS--------IHREAVPPPPPQ 288
Query: 1500 QRQPYMSS----SASMQPITRPPQPSYQTPPSLPNHIS-RAPSPASFQRSLENRMSPSKS 1554
+P + S SAS Q PP PS PP LP S +P QR+L S +
Sbjct: 289 NNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLS---LSSST 345
Query: 1555 PFLPSMKMQKVMPTVPTSQV----------TGPPPQPPPIRREITFPPGSVEASQPVLKQ 1604
P LPS +P P+ + +GP P PPP+ R GS + P Q
Sbjct: 346 PPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRN-----GSTSRALPATPQ 400
Score = 42.7 bits (99), Expect = 0.004
Identities = 49/185 (26%), Positives = 66/185 (35%), Gaps = 30/185 (16%)
Query: 75 PISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKM 134
P+ N S+ P P P +P +A QA PP PP S+PG PP +
Sbjct: 270 PVGNRPSIHREA--VPPPPPQNNKPPVPSTPRPSASSQAPPPPPP-PSRPG-----PPPL 321
Query: 135 GEPAGGRYEHPGLG----ALGTQQPPVAVPGGGG------GPAAVPEFNNYYGSAAP--- 181
+ G E P L +L + PP+ PG G P + G + P
Sbjct: 322 PPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP 381
Query: 182 ----ASGGPGGRAGPCFDQ---HGGQQSPGMGMMH--SASAAAAGAPGSMDPLQNSHEGY 232
+ G RA P Q G SP G +AGAP P + G+
Sbjct: 382 PPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGF 441
Query: 233 PNSQC 237
+S C
Sbjct: 442 QDSPC 446
Score = 40.0 bits (92), Expect = 0.026
Identities = 42/173 (24%), Positives = 61/173 (35%), Gaps = 25/173 (14%)
Query: 1420 IQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTD 1479
I +PP P Q++ P +A + P P PG P P G + T
Sbjct: 277 IHREAVPPP----PPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETP 332
Query: 1480 DMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSL---PNHISRAP 1536
+ P + ++ +S P + S P+ PP PS + PP + P P
Sbjct: 333 RL--PQRNLS--------LSSSTPPLPSPGRSGPL--PPPPSERPPPPVRDPPGRSGPLP 380
Query: 1537 SPASFQRSLENRMSPSKSPFLPSM------KMQKVMPTVPTSQVTGPPPQPPP 1583
P R+ + +P LPS + P P G PP PPP
Sbjct: 381 PPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPP 433
Score = 37.7 bits (86), Expect = 0.13
Identities = 48/182 (26%), Positives = 62/182 (34%), Gaps = 21/182 (11%)
Query: 83 GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRY 142
GG GGG G GG GG GPP L G PK+ A
Sbjct: 68 GGGGGGFGGGGG------FGGGGGGGGGGSFGGGGPPGLG--GLFQAGMPKLRSTANRDN 119
Query: 143 EHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQS 202
+ G +PP+ +P GG +A P F+ G PG R+GP Q
Sbjct: 120 DSGG------SRPPL-LPPGGRSTSAKP-FSPPSGPGRFPVPSPGHRSGPPEPQRNRMPP 171
Query: 203 PGMGMMHSASAAAAGAPGSMDPLQNSHEG-----YPNSQCNHYPGYSRPGAGGGGGGGGG 257
P + + P + P+Q+S P PG + P G G G
Sbjct: 172 PRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALG 231
Query: 258 GG 259
GG
Sbjct: 232 GG 233
Score = 37.7 bits (86), Expect = 0.13
Identities = 88/419 (21%), Positives = 137/419 (32%), Gaps = 81/419 (19%)
Query: 891 GSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGE 950
G PG+ GL + P + N + PP + P ++SA SP
Sbjct: 95 GGPPGLG--GLFQAGMPKLRSTANRDNDSGGSRPPL-LPPGGRSTSAKP------FSPPS 145
Query: 951 SKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGD 1010
P+ + G G P+P+ S+P + +P P P +P SS H
Sbjct: 146 GPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDS---IPPPVPSTPRPIQ-SSPHNR 201
Query: 1011 ESDSISSPGWPKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVS 1070
S + PG P+ PS P + G + T LG R+ + F P +
Sbjct: 202 GSPPV--PGGPRQPS-PGPTPPPFPGNRGTA---LGGGSIRQSPLSSSSPFSNRPPLPPT 255
Query: 1071 SLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQY 1130
A+ KP +G +++ N S+ S Q
Sbjct: 256 PSRALDDKPPPP------PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQ---- 305
Query: 1131 LFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQ------------ 1178
PPP +P P P++SG+ + P+ PQ
Sbjct: 306 ----------APPPPPP-------PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPL 348
Query: 1179 -STGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMT 1237
S G + P +PP P P GRS + P S + S + T
Sbjct: 349 PSPGRSGPLPPPPSERPPPPVRDP--------PGRSGPLPPPPPVS--RNGSTSRALPAT 398
Query: 1238 PNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSP 1296
P P + G+ P R P P++ G P P++S+++ + SP
Sbjct: 399 PQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPP------------PSTSIRNGFQDSP 445
Score = 35.8 bits (81), Expect = 0.48
Identities = 49/181 (27%), Positives = 61/181 (33%), Gaps = 31/181 (17%)
Query: 87 GGAPQPGPDMEQPQHGGAKDSAAGGQA--------------DPPGPPLLSKPGDEDDAPP 132
GG QP P P G + +A GG + PP PP S+ DD PP
Sbjct: 208 GGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA--LDDKPP 265
Query: 133 KMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSA-APASGGPGGRAG 191
P G R P + PP P P VP S+ AP P R G
Sbjct: 266 PPPPPVGNR---PSIHREAVPPPP---PQNNKPP--VPSTPRPSASSQAPPPPPPPSRPG 317
Query: 192 P---CFDQHGGQQSPGM---GMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSR 245
P G ++P + + S+S +PG PL P PG S
Sbjct: 318 PPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSG 377
Query: 246 P 246
P
Sbjct: 378 P 378
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 97.4 bits (241), Expect = 1e-19
Identities = 130/490 (26%), Positives = 157/490 (32%), Gaps = 129/490 (26%)
Query: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY 300
P +P G GGGGGG GGG G GGGGGG G G + GGGG G
Sbjct: 57 PILDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGG----------------SFGGGGPPGL 100
Query: 301 GG-SSAGYGVLSSPRQQ-----GGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHP 354
GG AG L S + G + P GG + S + S G F H
Sbjct: 101 GGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFP--VPSPGHR 158
Query: 355 SGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAG 414
SG + P P + GS P+ S PPP PS P+
Sbjct: 159 SGPPEPQRNRMPPPRPDV----GSKPD----SIPPPVPSTPR------------------ 192
Query: 415 MGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMG 474
Q H SP PG S G P R G G
Sbjct: 193 -------------------PIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGG 233
Query: 475 SNPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGY 534
S S SSP+ PP P R A P PP
Sbjct: 234 SIRQSPLSSSSPFSNRPPLPPTPSR-------------ALDDKPPPPPPP---------- 270
Query: 535 CQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHE 594
G +P ++ PP PPQ P S P+ S + PP P +P
Sbjct: 271 --VGNRPSIHREAVPPP-PPQNNKPPVPS----TPRPSASSQA----PPPPPPPSRPG-- 317
Query: 595 DLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHAS 654
P LP S D+ P + LS +S+S +S P P S
Sbjct: 318 ---------PPPLPPSSSGNDETPRLPQRNLS--LSSSTPPLPSPGRSGPLPPPPSERPP 366
Query: 655 PHLSSIPGGPSPSPVGSPVGSN-------------QSRSGPISPASIPGSQMPPQPPGSQ 701
P + PG P P PV N SRSG SP S P +PP P +
Sbjct: 367 PPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAG 426
Query: 702 SESSSHPALS 711
+ P+ S
Sbjct: 427 APPPPPPSTS 436
Score = 57.8 bits (138), Expect = 1e-07
Identities = 100/451 (22%), Positives = 152/451 (33%), Gaps = 49/451 (10%)
Query: 447 TPGPTMGRSQGSPMDPM---VMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIG 503
T PT+ +++ + + + + K +L +N S P P G+ G G G
Sbjct: 20 TEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDKPKGAGAGGGGGGFGGGGG 79
Query: 504 IQGRTPGAMAGMQYPQQQMPPQYG---QQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLP 560
G G G PP G Q G+ + S +PP LPP +
Sbjct: 80 FGGGGGGGGGGSFGGGG--PPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGR--- 134
Query: 561 SQSQQRYQPQQDMSQ---EGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDL 617
S S + + P + G RS PP +P + P PD+ D +
Sbjct: 135 STSAKPFSPPSGPGRFPVPSPGHRSGPP----EPQRNRM-------PPPRPDVGSKPDSI 183
Query: 618 PTGTEAT---LSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPS--PSPVGSP 672
P +T + S+ GS G P+ P P + + GG S SP+ S
Sbjct: 184 PPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSS 243
Query: 673 VGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMA 732
+ P +P+ + PP PP + S H P PQ + P +
Sbjct: 244 SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSAS 303
Query: 733 QYGPQQTGPSMSPHPSPGGQMHAGISSF----QQSNSSGTYGPQMSQYGPQGNYSRPPAY 788
P P P P P +G Q++ S + P + G G PP+
Sbjct: 304 SQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE 363
Query: 789 SGVPSA----SYSGP-GPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMS 843
P SGP P +S N P+ P ++PS + P G
Sbjct: 364 RPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATP-------QLPSRSGVDSPRSGPRP 416
Query: 844 SMTPSSPGMSQQGGPGMGPPMPTVNRKAQEA 874
+ P P G P PP ++ Q++
Sbjct: 417 PLPPDRP---SAGAPPPPPPSTSIRNGFQDS 444
Score = 51.6 bits (122), Expect = 9e-06
Identities = 74/308 (24%), Positives = 105/308 (34%), Gaps = 80/308 (25%)
Query: 747 PSPGGQMHAGI----SSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPG 802
P GG AG+ S+ + N SG P + G + ++P + P + P PG
Sbjct: 98 PGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGR-FPVPSPG 156
Query: 803 MGISANNQMHGQGPSQP-----------CGAVPLGRMPSAGMQNRPF---PGNMSSMTPS 848
H GP +P G+ P P RP P N S P
Sbjct: 157 ---------HRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGS--PP 205
Query: 849 SPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQ--SRQGSFPGMNQSGLMASSS 906
PG +Q PG PP NR ++ Q+ +S+ S + P L
Sbjct: 206 VPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP 265
Query: 907 PYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGT 966
P P+ N S+ PP P +K P+P T
Sbjct: 266 PPPPPVGNRPSIHREAVPP--------------------PPPQNNKPPVP--------ST 297
Query: 967 PQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSS 1026
P+P + S+ PP P + P P P+ PSS+ DE+ P+ P
Sbjct: 298 PRPSASSQ-------APPPPPPPSRPGPPPLPPSSSG-----NDET--------PRLPQR 337
Query: 1027 PKSSSSTT 1034
S SS+T
Sbjct: 338 NLSLSSST 345
Score = 47.8 bits (112), Expect = 1e-04
Identities = 82/300 (27%), Positives = 106/300 (35%), Gaps = 66/300 (22%)
Query: 1329 PGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEG---DMYNMQYSSQ---- 1381
P GP P GH+ G P +P R PP + G D S
Sbjct: 143 PPSGPGRFPVPSPGHRSG--PPEPQRNRM------PPPRPDVGSKPDSIPPPVPSTPRPI 194
Query: 1382 QQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSS--SS 1439
Q +N+ G R+P G P P+ R G GG ++ S SS
Sbjct: 195 QSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALG------------GGSIRQSPLSS 242
Query: 1440 EGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVS 1499
P N R +P P +R P PP G NR I+ E+ P
Sbjct: 243 SSPFSN----RPPLP-PTPSRALDDKPPPPPPPVG-NRPS--------IHREAVPPPPPQ 288
Query: 1500 QRQPYMSS----SASMQPITRPPQPSYQTPPSLPNHIS-RAPSPASFQRSLENRMSPSKS 1554
+P + S SAS Q PP PS PP LP S +P QR+L S +
Sbjct: 289 NNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLS---LSSST 345
Query: 1555 PFLPSMKMQKVMPTVPTSQV----------TGPPPQPPPIRREITFPPGSVEASQPVLKQ 1604
P LPS +P P+ + +GP P PPP+ R GS + P Q
Sbjct: 346 PPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRN-----GSTSRALPATPQ 400
Score = 42.7 bits (99), Expect = 0.004
Identities = 49/185 (26%), Positives = 66/185 (35%), Gaps = 30/185 (16%)
Query: 75 PISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKM 134
P+ N S+ P P P +P +A QA PP PP S+PG PP +
Sbjct: 270 PVGNRPSIHREA--VPPPPPQNNKPPVPSTPRPSASSQAPPPPPP-PSRPG-----PPPL 321
Query: 135 GEPAGGRYEHPGLG----ALGTQQPPVAVPGGGG------GPAAVPEFNNYYGSAAP--- 181
+ G E P L +L + PP+ PG G P + G + P
Sbjct: 322 PPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP 381
Query: 182 ----ASGGPGGRAGPCFDQ---HGGQQSPGMGMMH--SASAAAAGAPGSMDPLQNSHEGY 232
+ G RA P Q G SP G +AGAP P + G+
Sbjct: 382 PPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGF 441
Query: 233 PNSQC 237
+S C
Sbjct: 442 QDSPC 446
Score = 40.0 bits (92), Expect = 0.026
Identities = 42/173 (24%), Positives = 61/173 (35%), Gaps = 25/173 (14%)
Query: 1420 IQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTD 1479
I +PP P Q++ P +A + P P PG P P G + T
Sbjct: 277 IHREAVPPP----PPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETP 332
Query: 1480 DMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSL---PNHISRAP 1536
+ P + ++ +S P + S P+ PP PS + PP + P P
Sbjct: 333 RL--PQRNLS--------LSSSTPPLPSPGRSGPL--PPPPSERPPPPVRDPPGRSGPLP 380
Query: 1537 SPASFQRSLENRMSPSKSPFLPSM------KMQKVMPTVPTSQVTGPPPQPPP 1583
P R+ + +P LPS + P P G PP PPP
Sbjct: 381 PPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPP 433
Score = 37.7 bits (86), Expect = 0.13
Identities = 48/182 (26%), Positives = 62/182 (34%), Gaps = 21/182 (11%)
Query: 83 GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRY 142
GG GGG G GG GG GPP L G PK+ A
Sbjct: 68 GGGGGGFGGGGG------FGGGGGGGGGGSFGGGGPPGLG--GLFQAGMPKLRSTANRDN 119
Query: 143 EHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQS 202
+ G +PP+ +P GG +A P F+ G PG R+GP Q
Sbjct: 120 DSGG------SRPPL-LPPGGRSTSAKP-FSPPSGPGRFPVPSPGHRSGPPEPQRNRMPP 171
Query: 203 PGMGMMHSASAAAAGAPGSMDPLQNSHEG-----YPNSQCNHYPGYSRPGAGGGGGGGGG 257
P + + P + P+Q+S P PG + P G G G
Sbjct: 172 PRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALG 231
Query: 258 GG 259
GG
Sbjct: 232 GG 233
Score = 37.7 bits (86), Expect = 0.13
Identities = 88/419 (21%), Positives = 137/419 (32%), Gaps = 81/419 (19%)
Query: 891 GSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGE 950
G PG+ GL + P + N + PP + P ++SA SP
Sbjct: 95 GGPPGLG--GLFQAGMPKLRSTANRDNDSGGSRPPL-LPPGGRSTSAKP------FSPPS 145
Query: 951 SKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGD 1010
P+ + G G P+P+ S+P + +P P P +P SS H
Sbjct: 146 GPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDS---IPPPVPSTPRPIQ-SSPHNR 201
Query: 1011 ESDSISSPGWPKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVS 1070
S + PG P+ PS P + G + T LG R+ + F P +
Sbjct: 202 GSPPV--PGGPRQPS-PGPTPPPFPGNRGTA---LGGGSIRQSPLSSSSPFSNRPPLPPT 255
Query: 1071 SLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQY 1130
A+ KP +G +++ N S+ S Q
Sbjct: 256 PSRALDDKPPPP------PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQ---- 305
Query: 1131 LFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQ------------ 1178
PPP +P P P++SG+ + P+ PQ
Sbjct: 306 ----------APPPPPP-------PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPL 348
Query: 1179 -STGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMT 1237
S G + P +PP P P GRS + P S + S + T
Sbjct: 349 PSPGRSGPLPPPPSERPPPPVRDP--------PGRSGPLPPPPPVS--RNGSTSRALPAT 398
Query: 1238 PNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSP 1296
P P + G+ P R P P++ G P P++S+++ + SP
Sbjct: 399 PQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPP------------PSTSIRNGFQDSP 445
Score = 35.8 bits (81), Expect = 0.48
Identities = 49/181 (27%), Positives = 61/181 (33%), Gaps = 31/181 (17%)
Query: 87 GGAPQPGPDMEQPQHGGAKDSAAGGQA--------------DPPGPPLLSKPGDEDDAPP 132
GG QP P P G + +A GG + PP PP S+ DD PP
Sbjct: 208 GGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA--LDDKPP 265
Query: 133 KMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSA-APASGGPGGRAG 191
P G R P + PP P P VP S+ AP P R G
Sbjct: 266 PPPPPVGNR---PSIHREAVPPPP---PQNNKPP--VPSTPRPSASSQAPPPPPPPSRPG 317
Query: 192 P---CFDQHGGQQSPGM---GMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSR 245
P G ++P + + S+S +PG PL P PG S
Sbjct: 318 PPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSG 377
Query: 246 P 246
P
Sbjct: 378 P 378
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 119,404,047
Number of Sequences: 37866
Number of extensions: 8089521
Number of successful extensions: 162693
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1393
Number of HSP's successfully gapped in prelim test: 2350
Number of HSP's that attempted gapping in prelim test: 51904
Number of HSP's gapped (non-prelim): 54366
length of query: 2231
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2113
effective length of database: 13,779,330
effective search space: 29115724290
effective search space used: 29115724290
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.