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Search of human proteins with 39995071
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|39995071 exonuclease 1 isoform b [Homo sapiens]
(846 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|39995071 exonuclease 1 isoform b [Homo sapiens] 1697 0.0
gi|18491016 exonuclease 1 isoform b [Homo sapiens] 1697 0.0
gi|39995069 exonuclease 1 isoform a [Homo sapiens] 1606 0.0
gi|4758356 flap structure-specific endonuclease 1 [Homo sapiens] 102 2e-21
gi|194018535 Gen homolog 1, endonuclease [Homo sapiens] 59 2e-08
gi|194018531 Gen homolog 1, endonuclease [Homo sapiens] 59 2e-08
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 57 9e-08
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 50 1e-05
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 50 1e-05
gi|51988900 XPG-complementing protein [Homo sapiens] 46 1e-04
gi|239749213 PREDICTED: mucin 3B, cell surface associated, parti... 43 0.001
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa... 42 0.002
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 42 0.003
gi|33469987 asteroid homolog 1 [Homo sapiens] 41 0.004
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 41 0.005
gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H... 41 0.005
gi|239755326 PREDICTED: hypothetical protein [Homo sapiens] 40 0.009
gi|24308334 family with sequence similarity 120B [Homo sapiens] 40 0.009
gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens] 40 0.012
gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens] 40 0.012
gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens] 40 0.012
gi|239744133 PREDICTED: hypothetical protein [Homo sapiens] 40 0.012
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 40 0.012
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H... 39 0.016
gi|153792780 additional sex combs like 2 [Homo sapiens] 39 0.020
gi|223029510 echinoderm microtubule associated protein like 4 is... 39 0.026
gi|19923497 echinoderm microtubule associated protein like 4 iso... 39 0.026
gi|157384986 transducin-like enhancer protein 3 isoform b [Homo ... 39 0.026
gi|157384984 transducin-like enhancer protein 3 isoform c [Homo ... 39 0.026
gi|157384982 transducin-like enhancer protein 3 isoform a [Homo ... 39 0.026
>gi|39995071 exonuclease 1 isoform b [Homo sapiens]
Length = 846
Score = 1697 bits (4394), Expect = 0.0
Identities = 846/846 (100%), Positives = 846/846 (100%)
Query: 1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM 60
MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
Sbjct: 1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM 60
Query: 61 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT 120
KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
Sbjct: 61 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT 120
Query: 121 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK 180
RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
Sbjct: 121 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK 180
Query: 181 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK 240
KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
Sbjct: 181 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK 240
Query: 241 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA 300
VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
Sbjct: 241 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA 300
Query: 301 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT 360
YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
Sbjct: 301 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT 360
Query: 361 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP 420
CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
Sbjct: 361 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP 420
Query: 421 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR 480
RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
Sbjct: 421 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR 480
Query: 481 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES 540
NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
Sbjct: 481 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES 540
Query: 541 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP 600
EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
Sbjct: 541 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP 600
Query: 601 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS 660
TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
Sbjct: 601 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS 660
Query: 661 DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS 720
DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
Sbjct: 661 DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS 720
Query: 721 KLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN 780
KLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
Sbjct: 721 KLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN 780
Query: 781 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV 840
AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
Sbjct: 781 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV 840
Query: 841 QRAIFQ 846
QRAIFQ
Sbjct: 841 QRAIFQ 846
>gi|18491016 exonuclease 1 isoform b [Homo sapiens]
Length = 846
Score = 1697 bits (4394), Expect = 0.0
Identities = 846/846 (100%), Positives = 846/846 (100%)
Query: 1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM 60
MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
Sbjct: 1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM 60
Query: 61 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT 120
KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
Sbjct: 61 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT 120
Query: 121 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK 180
RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
Sbjct: 121 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK 180
Query: 181 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK 240
KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
Sbjct: 181 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK 240
Query: 241 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA 300
VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
Sbjct: 241 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA 300
Query: 301 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT 360
YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
Sbjct: 301 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT 360
Query: 361 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP 420
CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
Sbjct: 361 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP 420
Query: 421 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR 480
RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
Sbjct: 421 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR 480
Query: 481 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES 540
NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
Sbjct: 481 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES 540
Query: 541 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP 600
EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
Sbjct: 541 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP 600
Query: 601 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS 660
TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
Sbjct: 601 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS 660
Query: 661 DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS 720
DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
Sbjct: 661 DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS 720
Query: 721 KLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN 780
KLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
Sbjct: 721 KLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN 780
Query: 781 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV 840
AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV
Sbjct: 781 AENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRV 840
Query: 841 QRAIFQ 846
QRAIFQ
Sbjct: 841 QRAIFQ 846
>gi|39995069 exonuclease 1 isoform a [Homo sapiens]
Length = 803
Score = 1606 bits (4158), Expect = 0.0
Identities = 802/802 (100%), Positives = 802/802 (100%)
Query: 1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM 60
MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM
Sbjct: 1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM 60
Query: 61 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT 120
KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT
Sbjct: 61 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT 120
Query: 121 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK 180
RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK
Sbjct: 121 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK 180
Query: 181 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK 240
KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK
Sbjct: 181 KVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACK 240
Query: 241 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA 300
VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA
Sbjct: 241 VLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNA 300
Query: 301 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT 360
YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT
Sbjct: 301 YEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKT 360
Query: 361 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP 420
CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP
Sbjct: 361 CQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRP 420
Query: 421 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR 480
RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR
Sbjct: 421 RSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTR 480
Query: 481 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES 540
NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES
Sbjct: 481 NKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES 540
Query: 541 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP 600
EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP
Sbjct: 541 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP 600
Query: 601 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS 660
TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS
Sbjct: 601 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS 660
Query: 661 DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS 720
DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS
Sbjct: 661 DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTS 720
Query: 721 KLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN 780
KLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN
Sbjct: 721 KLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHN 780
Query: 781 AENKPGLQIKLNELWKNFGFKK 802
AENKPGLQIKLNELWKNFGFKK
Sbjct: 781 AENKPGLQIKLNELWKNFGFKK 802
>gi|4758356 flap structure-specific endonuclease 1 [Homo sapiens]
Length = 380
Score = 102 bits (253), Expect = 2e-21
Identities = 90/302 (29%), Positives = 146/302 (48%), Gaps = 23/302 (7%)
Query: 1 MGIQGLLQFIKEASEPI----HVRKYKGQVVAVDTYCWLHKGAIACAE-----KLAKGEP 51
MGIQGL + I + + ++ Y G+ VA+D +++ IA + + +GE
Sbjct: 1 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET 60
Query: 52 TDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGK 111
T +G + + M+ +GIKP+ VFDG P K E ++R R+A K Q +
Sbjct: 61 TSHLMGMFYRTIRMM-ENGIKPVYVFDGKP-PQLKSGELAKRSERRAEAEKQLQQAQAAG 118
Query: 112 VSEARECFT-RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITE 170
+ E FT R + +T + G+ L AP EA+A A L KAG V A TE
Sbjct: 119 AEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATE 178
Query: 171 DSDLLAFGCKKVILKMD-QFGNGLEIDQARLG-MCRQLGDVFTEEKFRYMCILSGCDYLS 228
D D L FG ++ + L I + L + ++LG +E+F +CIL G DY
Sbjct: 179 DMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELG--LNQEQFVDLCILLGSDYCE 236
Query: 229 SLRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVF 288
S+RGIG +A +++ + I ++++++ VPE++++ A+ FL V
Sbjct: 237 SIRGIGPKRAVDLIQ--KHKSIEEIVRRLD---PNKYPVPENWLHK--EAHQLFLEPEVL 289
Query: 289 DP 290
DP
Sbjct: 290 DP 291
>gi|194018535 Gen homolog 1, endonuclease [Homo sapiens]
Length = 908
Score = 58.5 bits (140), Expect = 2e-08
Identities = 54/254 (21%), Positives = 105/254 (41%), Gaps = 20/254 (7%)
Query: 1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM 60
MG+ L Q ++ + I +R G+ +AVD W+ + + +P R + F +
Sbjct: 1 MGVNDLWQILEPVKQHIPLRNLGGKTIAVDLSLWVCEAQTVKKMMGSVMKPHLRNLFFRI 60
Query: 61 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT 120
++ + +K + V +G K +V R + R + GK ++ S +
Sbjct: 61 SYLTQM---DVKLVFVMEGEPPKLKADVISKRNQSRYGS--SGKSWSQKTGRSHFKSVLR 115
Query: 121 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK 180
+++ + G+ + A EA+A AYLN G V +T D D +G +
Sbjct: 116 ECLHMLECL-----------GIPWVQAAGEAEAMCAYLNAGGHVDGCLTNDGDTFLYGAQ 164
Query: 181 KVILKMDQFGNGLEIDQARLGMCR-QLGDVFTEEKFRYMCILSGCDYL-SSLRGIGLAKA 238
V +D + + +LG + + IL GCDYL + G+G +A
Sbjct: 165 TVYRNFTMNTKDPHVDCYTMSSIKSKLG--LDRDALVGLAILLGCDYLPKGVPGVGKEQA 222
Query: 239 CKVLRLANNPDIVK 252
K++++ +++
Sbjct: 223 LKLIQILKGQSLLQ 236
>gi|194018531 Gen homolog 1, endonuclease [Homo sapiens]
Length = 908
Score = 58.5 bits (140), Expect = 2e-08
Identities = 54/254 (21%), Positives = 105/254 (41%), Gaps = 20/254 (7%)
Query: 1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM 60
MG+ L Q ++ + I +R G+ +AVD W+ + + +P R + F +
Sbjct: 1 MGVNDLWQILEPVKQHIPLRNLGGKTIAVDLSLWVCEAQTVKKMMGSVMKPHLRNLFFRI 60
Query: 61 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFT 120
++ + +K + V +G K +V R + R + GK ++ S +
Sbjct: 61 SYLTQM---DVKLVFVMEGEPPKLKADVISKRNQSRYGS--SGKSWSQKTGRSHFKSVLR 115
Query: 121 RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCK 180
+++ + G+ + A EA+A AYLN G V +T D D +G +
Sbjct: 116 ECLHMLECL-----------GIPWVQAAGEAEAMCAYLNAGGHVDGCLTNDGDTFLYGAQ 164
Query: 181 KVILKMDQFGNGLEIDQARLGMCR-QLGDVFTEEKFRYMCILSGCDYL-SSLRGIGLAKA 238
V +D + + +LG + + IL GCDYL + G+G +A
Sbjct: 165 TVYRNFTMNTKDPHVDCYTMSSIKSKLG--LDRDALVGLAILLGCDYLPKGVPGVGKEQA 222
Query: 239 CKVLRLANNPDIVK 252
K++++ +++
Sbjct: 223 LKLIQILKGQSLLQ 236
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 56.6 bits (135), Expect = 9e-08
Identities = 92/447 (20%), Positives = 159/447 (35%), Gaps = 26/447 (5%)
Query: 303 DDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKTCQ 362
D D S + D S + + + N+ + D + + + + S S D
Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792
Query: 363 KSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRPRS 422
S++ S N S S SD+ ++ S+ + S+ + S S
Sbjct: 793 DSSDSS-----NSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDS 847
Query: 423 AELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTRNK 482
++ S+ D ++ S + + +S N S S + N + S ++ +
Sbjct: 848 SDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSD 907
Query: 483 FATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHESEY 542
+ + + + + S +S+S+D ++ S D + +D N+ S
Sbjct: 908 SSNSSDSSDSSNSSDSSESSNSSD--NSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNS 965
Query: 543 GDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPPTL 602
D D+ + NSSD ++ D + + + S S +SS + +
Sbjct: 966 SDSSDSNSSDSSDSSNSSDSSDSSD-SSDSSDSSDSSNSSDSSDSSDSSDSSNS------ 1018
Query: 603 GTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESSDD 662
S S D S + S S+ SDS S +N SD S S D
Sbjct: 1019 -------SDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1071
Query: 663 ESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTSKL 722
S + + SS S ES + S SSN+S S S S+ SD + S S +S
Sbjct: 1072 SS----DSSDSSDSSESSDSS-DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1126
Query: 723 CLSHFSKKDTPLRNKVPGLYKSSSADS 749
S S + N S S+DS
Sbjct: 1127 SDSSDSSDSSDSSNSSDSSDSSESSDS 1153
Score = 55.1 bits (131), Expect = 3e-07
Identities = 94/421 (22%), Positives = 156/421 (37%), Gaps = 34/421 (8%)
Query: 331 DINTFEQIDDYNPDTAMPAHSRSHSWDDKTCQKSANVSSIWHRNYSPRPESGTVSDAPQL 390
D ++ + D N + + S+S D + +N SS N S +S SD+
Sbjct: 852 DSDSSNRSDSSNSSDSSDSSDSSNS-SDSSDSSDSNESS----NSSDSSDSSNSSDSDSS 906
Query: 391 KENPSTVGVERVISTKGLNLPRKSSIVKRPRSAELSEDDLLSQYSLSFTKKTKKNSSEGN 450
+ S+ + S+ + S+ S++ S S S S NSS+ +
Sbjct: 907 DSSNSSDSSD---SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSS 963
Query: 451 KSLSFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATFLQRKNEESGAVVVPGTRSRFFCSS 510
S S+ D + + S + + + ++ ++ S SS
Sbjct: 964 NSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSD-------------SS 1010
Query: 511 DSTDCVSNKVSIQPLDETAVTDKENNLHESEYGDQEGKRLVDTDVARNSSD--DIPNNHI 568
DS+D ++ S D + +D ++ S+ D D+ + NSSD D ++
Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSS--DSSDSSNSSDSSDSSDSSD 1068
Query: 569 PGDHIPDKATVFTDEESYSFESSKFTRTISPPTLGTLRSCFSWSGGLGDFSRTPSPSPST 628
D + + E S S +SS + + S S S D S + S S+
Sbjct: 1069 SSDSSDSSDSSDSSESSDSSDSSNSSDSSDS-------SDSSDSSDSSDSSDSSDSSDSS 1121
Query: 629 ALQQFRRKSDSPTSLPENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEFSLQSSN 688
SDS S +N SD S SE S +S + + SS S +S + S SSN
Sbjct: 1122 NSSDSSDSSDSSDSSDSSNSSDSSD-SSESSDSSDSSDSSDSSDSSDSSDSSDSS-DSSN 1179
Query: 689 ASKLSQCSSKDSDSEESDCNIKLLDSQSDQTSKLCLSHFSKKDTPLRNKVPGLYKSSSAD 748
+S S S S+ SD + S S +S S S + + S S+D
Sbjct: 1180 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSD 1239
Query: 749 S 749
S
Sbjct: 1240 S 1240
Score = 54.3 bits (129), Expect = 5e-07
Identities = 91/410 (22%), Positives = 146/410 (35%), Gaps = 21/410 (5%)
Query: 304 DVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKTCQK 363
D D S + D S + + + + D N + + S+S D
Sbjct: 902 DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961
Query: 364 SANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRPRSA 423
S+N S N S +S SD+ ++ + S+ N S S+
Sbjct: 962 SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSD-----SSDSSNSSDSSDSSDSSDSS 1016
Query: 424 ELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTRNKF 483
S+ S S S +SS+ + S S+ D N + S + + +
Sbjct: 1017 NSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDS--SDSSNSSDSSDSSDSSDSSDSSD 1074
Query: 484 ATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHESEYG 543
++ +E S + S SSDS+D + S D + +D N+ S+
Sbjct: 1075 SSDSSDSSESSDS----SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130
Query: 544 DQEGKRLVDTDVARNSSD--DIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTI--SP 599
D D+ + NSSD D + D + + + S S +SS + + S
Sbjct: 1131 DSS-----DSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1185
Query: 600 PTLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLK-SEE 658
+ + S S S D S + S S+ SDS S N SD S S +
Sbjct: 1186 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSD 1245
Query: 659 SSDDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCN 708
SS+ + S S + E QS + + + S DSDSE SD N
Sbjct: 1246 SSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSN 1295
Score = 53.9 bits (128), Expect = 6e-07
Identities = 86/421 (20%), Positives = 151/421 (35%), Gaps = 6/421 (1%)
Query: 333 NTFEQIDDYNPDTAMPAHSRSHSWDDKTCQKSANVSSIWHRNYSPRPESGTVSDAPQLKE 392
N+ + D + D++ S D S++ S N S +S SD+ +
Sbjct: 559 NSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSD 618
Query: 393 NPSTVGVERVISTKGLNLPRKSSIVKRPRSAELSEDDLLSQYSLSFTKKTKKNSSEGNKS 452
+ + + + KS S++ S++ S S S +SS+ + S
Sbjct: 619 SSDSKSDSSKSESDSSDSDSKSDS-SDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDS 677
Query: 453 LSFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATFLQRKNEESGAVVVPGTRSRFFCSSDS 512
S S+ + ++ + S + + + ++ S + S SSDS
Sbjct: 678 SSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSN---SSDS 734
Query: 513 TDCVSNKVSIQPLDETAVTDKENNLHESEYGD-QEGKRLVDTDVARNSSDDIPNNHIPGD 571
+D ++ S D + +D ++ S D + D+ + NSSD +++ D
Sbjct: 735 SDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSN-SSD 793
Query: 572 HIPDKATVFTDEESYSFESSKFTRTISPPTLGTLRSCFSWSGGLGDFSRTPSPSPSTALQ 631
+ + S S +SS + + S + + S S S S S +
Sbjct: 794 SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDS 853
Query: 632 QFRRKSDSPTSLPENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEFSLQSSNASK 691
+SDS S ++ SD S S D + S S S S SSN+S
Sbjct: 854 DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913
Query: 692 LSQCSSKDSDSEESDCNIKLLDSQSDQTSKLCLSHFSKKDTPLRNKVPGLYKSSSADSLS 751
S S+ SE S+ + S S +S S S + N S S+DS S
Sbjct: 914 SSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973
Query: 752 T 752
+
Sbjct: 974 S 974
Score = 53.9 bits (128), Expect = 6e-07
Identities = 85/417 (20%), Positives = 152/417 (36%), Gaps = 17/417 (4%)
Query: 333 NTFEQIDDYNPDTAMPAHSRSHSWDDKTCQKSANVSSIWHRNYSPRPESGTVSDAPQLKE 392
N+ + D + + + S+S D S+N S + S +S SD+
Sbjct: 664 NSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDS----S 719
Query: 393 NPSTVGVERVISTKGLNLPRKSSIVKRPRSAELSEDDLLSQYSLSFTKKTKKNSSEGNKS 452
N ++ + S+ + S S+ S+ S S S +SS+ + S
Sbjct: 720 NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS 779
Query: 453 LSFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATFLQRKNEESGAVVVPGTRSRFFCSSDS 512
+ S+ + ++ S S+ + + + + S SSDS
Sbjct: 780 SNSSD-------SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDS 832
Query: 513 TDCVSNKVSIQPLDETAVTDKENNLHESEYGDQEGKRLVDTDVARNSSDDIPNNHIPGDH 572
+D ++ S D + +D +++ + D+ + +SSD +N
Sbjct: 833 SDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS 892
Query: 573 IPDKATVFTDEESYSFESSKFTRTISPPTLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQ 632
++ +D +S +S + S + + S S + D S + S S+
Sbjct: 893 DSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSS---D 949
Query: 633 FRRKSDSPTSLPENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEFSLQSSNASKL 692
SDS S +N SD S S +SSD + + + SS S +S + S SSN+S
Sbjct: 950 SSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNS--SDSSDSSDSSDSSD-SSDSSNSSDS 1006
Query: 693 SQCSSKDSDSEESDCNIKLLDSQSDQTSKLCLSHFSKKDTPLRNKVPGLYKSSSADS 749
S S S SD + S S +S S S + + S S+DS
Sbjct: 1007 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1063
Score = 52.0 bits (123), Expect = 2e-06
Identities = 92/450 (20%), Positives = 172/450 (38%), Gaps = 8/450 (1%)
Query: 303 DDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKTCQ 362
D D + S + D S + + ++ ++ + D + D++ ++S S D
Sbjct: 673 DSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSS 732
Query: 363 KSANVSSIWHRNYSPRPESGTVSDAPQLKENP-STVGVERVISTKGLNLPRKSSIVKRPR 421
S++ S+ + S +S SD+ ++ S+ + S+ + S
Sbjct: 733 DSSDSSN--SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSN 790
Query: 422 SAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTRN 481
S++ S+ S S S +SS+ + S S D + + S + +
Sbjct: 791 SSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDG 850
Query: 482 KFATFLQRKNEESGAVVVPGT-RSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHES 540
+ R + + + + S SSDS+D + S D + +D +++ +
Sbjct: 851 SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSN 910
Query: 541 EYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPP 600
+ D+ + NSSD+ ++ ++ ++ S S + S
Sbjct: 911 SSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 970
Query: 601 TLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESS 660
+ + S S S D S + S S+ SDS S +N SD S S+ S+
Sbjct: 971 SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSN-SSDSSN 1029
Query: 661 DDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSD-SEESDCNIKLLDSQSDQT 719
+S + + SS S +S + S SSN+S S SS SD S+ SD + S+S +
Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSS-DSSNSSDSSD-SSDSSDSSDSSDSSDSSDSSESSDS 1087
Query: 720 SKLCLSHFSKKDTPLRNKVPGLYKSSSADS 749
S S S + + S S+DS
Sbjct: 1088 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117
Score = 44.7 bits (104), Expect = 4e-04
Identities = 59/241 (24%), Positives = 94/241 (39%), Gaps = 15/241 (6%)
Query: 509 SSDSTDCVSNKVSIQPLDETAVTDKENNLHESEYGDQEGKRLVDTDVARNSSDDIPNNHI 568
+SD+ + SN D+ +D +S D D+ + +SSD ++
Sbjct: 518 TSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSS-----DSSNSSDSSDSSDSDSS 572
Query: 569 PGDHIPDKATVFTDEESYSFESSKFTRTISPPTLGTLRSCFSWSGGLGDFSRTPSPSPST 628
+ D + +D S S + S + + S S S D S S S+
Sbjct: 573 DSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSD-----SKSDSS 627
Query: 629 ALQQFRRKSDSPTSLPENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEFSLQSSN 688
+ SDS + ++N SD S S+ S S + + SS S +S S SSN
Sbjct: 628 KSESDSSDSDSKSDSSDSNSSDSSD-NSDSSDSSNSSNSSDSSDSSDSSDSSSSS-DSSN 685
Query: 689 ASKLSQCSSKDSDSEESDCNIKLLDSQSDQTSKLCLSHFSKKDTPLRNKVPGLYKSSSAD 748
+S S S + SE SD + S SD + S+ + D+ N S+S+D
Sbjct: 686 SSDSSDSSDSSNSSESSDSSD---SSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD 742
Query: 749 S 749
S
Sbjct: 743 S 743
Score = 44.7 bits (104), Expect = 4e-04
Identities = 38/140 (27%), Positives = 57/140 (40%), Gaps = 3/140 (2%)
Query: 614 GLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESSDDESHPLREGACS 673
G D S + S S + + ++ SD S S +SSD +S + S
Sbjct: 545 GKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDS 604
Query: 674 SQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTSKLCLSHFSKKDTP 733
S S +S + S S ++ S S +SDS +SD DS S +S S S +
Sbjct: 605 SDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSS- 663
Query: 734 LRNKVPGLYKSSSADSLSTT 753
N S S+DS S++
Sbjct: 664 --NSSDSSDSSDSSDSSSSS 681
Score = 30.8 bits (68), Expect = 5.5
Identities = 30/121 (24%), Positives = 47/121 (38%), Gaps = 8/121 (6%)
Query: 636 KSDSPTSLPENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEFSLQSSNASKLSQC 695
+ D S + N SD + + + D++ +G S +S + SSN+S
Sbjct: 511 EDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSD----SSNSSD---- 562
Query: 696 SSKDSDSEESDCNIKLLDSQSDQTSKLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKI 755
SS SDS+ SD N SD S S + + S S+DS ++
Sbjct: 563 SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 622
Query: 756 K 756
K
Sbjct: 623 K 623
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 49.7 bits (117), Expect = 1e-05
Identities = 51/206 (24%), Positives = 77/206 (37%), Gaps = 9/206 (4%)
Query: 516 VSNKVSIQPLDETAVTDKENNLHESEYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPD 575
+ K I D+ + D N + E + E DT +++ P GD D
Sbjct: 267 IFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQ------PRRDSKGDSQED 320
Query: 576 KATVFTDEESYSFESSKFTRTISPPTLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRR 635
+ EES + + + + L + + + SR +P P+T+ + +
Sbjct: 321 SKENLSQEESQNVDGPS-SESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQE 379
Query: 636 KSDSPTSLPENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEFSLQSSNASKLSQC 695
SDS + +S EE +D ES S +S ES E SS S
Sbjct: 380 DSDSSEEDSSHTLSHSKSESREEQADSESSESLN--FSEESPESPEDENSSSQEGLQSHS 437
Query: 696 SSKDSDSEESDCNIKLLDSQSDQTSK 721
SS +S SEES DSQ SK
Sbjct: 438 SSAESQSEESHSEEDDSDSQDSSRSK 463
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 49.7 bits (117), Expect = 1e-05
Identities = 51/206 (24%), Positives = 77/206 (37%), Gaps = 9/206 (4%)
Query: 516 VSNKVSIQPLDETAVTDKENNLHESEYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPD 575
+ K I D+ + D N + E + E DT +++ P GD D
Sbjct: 251 IFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQ------PRRDSKGDSQED 304
Query: 576 KATVFTDEESYSFESSKFTRTISPPTLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRR 635
+ EES + + + + L + + + SR +P P+T+ + +
Sbjct: 305 SKENLSQEESQNVDGPS-SESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQE 363
Query: 636 KSDSPTSLPENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEFSLQSSNASKLSQC 695
SDS + +S EE +D ES S +S ES E SS S
Sbjct: 364 DSDSSEEDSSHTLSHSKSESREEQADSESSESLN--FSEESPESPEDENSSSQEGLQSHS 421
Query: 696 SSKDSDSEESDCNIKLLDSQSDQTSK 721
SS +S SEES DSQ SK
Sbjct: 422 SSAESQSEESHSEEDDSDSQDSSRSK 447
>gi|51988900 XPG-complementing protein [Homo sapiens]
Length = 1186
Score = 46.2 bits (108), Expect = 1e-04
Identities = 41/157 (26%), Positives = 66/157 (42%), Gaps = 7/157 (4%)
Query: 86 KEVERSRRERRQANLLKGKQLLREGKVSEARECFTRSINITHAMAHKVIKAARSQGVDCL 145
+++ E ++NLL + L+ K + R T +T M + + R G+ +
Sbjct: 729 QDINLEELETLESNLLAQQNSLKAQKQQQERIAAT----VTGQMFLESQELLRLFGIPYI 784
Query: 146 VAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQ 205
AP EA+AQ A L+ IT+DSD+ FG + V +E Q + Q
Sbjct: 785 QAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQ-YVDFHNQ 843
Query: 206 LGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACKVL 242
LG K + L G DY + +G A ++L
Sbjct: 844 LG--LDRNKLINLAYLLGSDYTEGIPTVGCVTAMEIL 878
Score = 40.8 bits (94), Expect = 0.005
Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 1/96 (1%)
Query: 1 MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCM 60
MG+QGL + ++ + + +G+++AVD WL++ ++ +
Sbjct: 1 MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFH 60
Query: 61 KFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERR 96
+ +L I+PI VFDG KK+ RR+R+
Sbjct: 61 RLCKLLFFR-IRPIFVFDGDAPLLKKQTLVKRRQRK 95
>gi|239749213 PREDICTED: mucin 3B, cell surface associated, partial
[Homo sapiens]
Length = 1063
Score = 43.1 bits (100), Expect = 0.001
Identities = 76/374 (20%), Positives = 144/374 (38%), Gaps = 35/374 (9%)
Query: 405 TKGLNLPRKSSIVKRPRSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLV 464
T + +S P ++ ++ ++ S + SFT K + + + SF+
Sbjct: 81 TSSITSTESTSHSTPPFTSSITTNETTSHSTPSFTTSITKTKTTSHSTPSFTSS------ 134
Query: 465 NGPTNKKSVSTPPRTRNKFATFLQRKNEES--GAVVVPGTRSRFFCS----------SDS 512
N T+ +S STPP T + + N S +++ T S S S S
Sbjct: 135 NSITDSRSHSTPPFTSSVTTPEMTSHNTPSFMSSIITTETTSHSTPSFTSSTIHSTVSSS 194
Query: 513 TDCVSNKVSIQPLDETAVTDKENNLHESEYGDQEGKRL----VDTDVARNSSDDIPNNHI 568
T +++ + T+ ++L ++ + L + T + ++ D+P+
Sbjct: 195 TTAITSPFTTAETGVTSTPSSPSSL-STDIPTTSLRTLTPLSLSTSTSLTTTTDLPSIPT 253
Query: 569 PGDHIPDKATVFTDEESY-SFESSKFTRTISPPTLGTLRSCFSWSGG--LGDFSRTPSPS 625
+P + + S S E+S T SP T+ T+R+ + + FS + +
Sbjct: 254 DISSLPTPIHIISSSPSIQSTETSSLVGTTSP-TMSTVRATLRSTENTPISSFSTSIVVT 312
Query: 626 PSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEFSLQ 685
P T Q S T + + S +SS H L S+ + +F +
Sbjct: 313 PETPTTQAPPVLMSATGTQTSPVPTTVTFGSMDSSTSTLHTLTPSTALSKIMSTSQFPIP 372
Query: 686 SSNASKLSQCSS----KDSDSEESDCNIKLLDSQSDQTSKLCLSHFSKKDTPLRNKVPGL 741
S+++S L S + S + S+ + S T+ + L+ FS T + + P +
Sbjct: 373 STHSSTLQTTPSIPSLQTSLTSTSEFTTESFTRGSTSTNAI-LTSFS---TIIWSSTPTI 428
Query: 742 YKSSSADSLSTTKI 755
SSS S S T +
Sbjct: 429 IMSSSPSSASITPV 442
>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
sapiens]
Length = 2881
Score = 42.0 bits (97), Expect = 0.002
Identities = 38/124 (30%), Positives = 54/124 (43%), Gaps = 9/124 (7%)
Query: 636 KSDSPTSLPENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEFSLQS-----SNAS 690
+++ T P + V + SE SSD +S R +CSS+S S S S S++S
Sbjct: 2108 RTEPLTPNPASKKPRVHKRGSESSSDSDSDSERS-SCSSRSSSSSSSSSCSHSRSGSSSS 2166
Query: 691 KLSQCSSKDSDSEESDCNIKLLDSQSDQTSKLCLSHFSKKDTPLRNKVPGLYKSSSADSL 750
S CSS S S S + S S + S K+++ K Y S SL
Sbjct: 2167 SSSSCSSASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRESTTHMKA---YDEESVASL 2223
Query: 751 STTK 754
STT+
Sbjct: 2224 STTQ 2227
Score = 30.4 bits (67), Expect = 7.2
Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 6/86 (6%)
Query: 622 PSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESSDD-ESHPLREGACSSQSQESG 680
P+ S S + SD +S + S++K +E E PL E S + G
Sbjct: 2801 PTLSQSNTFDVQNKNSDLGSSKSVEVKEEDSRIKDQEDKGGTEPSPLNEN-----STDEG 2855
Query: 681 EFSLQSSNASKLSQCSSKDSDSEESD 706
+S+ S + SS+DSDS D
Sbjct: 2856 SEKADASSGSDSTSSSSEDSDSSNED 2881
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 41.6 bits (96), Expect = 0.003
Identities = 75/315 (23%), Positives = 120/315 (38%), Gaps = 54/315 (17%)
Query: 437 SFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVST---PPRTRNKFATFLQ----- 488
SFT++TKK + EV VP + G KK S PP T KF +Q
Sbjct: 217 SFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTE-KFPAKIQPPLVE 275
Query: 489 --------RKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQP--LDETAVTDKENNLH 538
R EE+ V P T + +T N V +QP +E + + +
Sbjct: 276 EATAKAEPRPAEETHVQVQPSTEETPDAEA-ATAVAENSVKVQPPPAEEAPLVEFPAEIQ 334
Query: 539 ESEYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTIS 598
+ L+ ++ S+++ P+ P + +P A E+S S E
Sbjct: 335 PPSAEESPSVELL-AEILPPSAEESPSEEPPAEILPPPA-----EKSPSVE--------- 379
Query: 599 PPTLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEE 658
LG +RS S P P+ AL++ K + PT E ++DV L EE
Sbjct: 380 --LLGEIRSP---SAQKAPIEVQPLPAEG-ALEEAPAKVEPPTV--EETLADVQPLLPEE 431
Query: 659 SSDDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLL---DSQ 715
+ +E+ L+ E QS K++ +EE+ I+LL +
Sbjct: 432 APREEARELQLSTAMETPAEEAPTEFQSP--------LPKETTAEEASAEIQLLAATEPP 483
Query: 716 SDQTSKLCLSHFSKK 730
+D+T S S++
Sbjct: 484 ADETPAEARSPLSEE 498
>gi|33469987 asteroid homolog 1 [Homo sapiens]
Length = 679
Score = 41.2 bits (95), Expect = 0.004
Identities = 27/102 (26%), Positives = 43/102 (42%), Gaps = 2/102 (1%)
Query: 1 MGIQGLLQFIKEASEPIHVR-KYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFC 59
MGI+GL+ F+++ S K + + +D Y H+ + L G D +
Sbjct: 1 MGIRGLMSFVEDHSNEFFTDLKLRDTKIVIDGYALFHRLCFSSNLDLRYGGDYDSFADVV 60
Query: 60 MKFVNMLLSHGIKPILVFD-GCTLPSKKEVERSRRERRQANL 100
KF L + I P +V D GC + KK R R + +
Sbjct: 61 QKFFESLFACNICPYVVLDGGCDISDKKLTTLKDRAREKIQM 102
>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
sapiens]
Length = 756
Score = 40.8 bits (94), Expect = 0.005
Identities = 76/328 (23%), Positives = 129/328 (39%), Gaps = 43/328 (13%)
Query: 373 RNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRPRSAEL--SEDDL 430
R+ + P+ +VS Q +E+ S V + S K +P K++ +RP + E S +
Sbjct: 323 RSKTQTPQQRSVSS--QEEEHSSPV---KAPSVKRTPMPDKTATPERPPAPENAPSSKKI 377
Query: 431 LSQYSLSFTKKT----KKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATF 486
+ + +KT K S GN + ++ PD V PT +K V+ + +
Sbjct: 378 PAPDKVPSPEKTLTLGDKASIPGNSTSG--KIPAPDKV--PTPEKMVTPEDKASIPENSI 433
Query: 487 LQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHESEYGDQE 546
+ EE+ V P T R F +S P E DK N + GD+
Sbjct: 434 IP---EETLTVDKPSTPERVFSVEES-----------PALEAPPMDKVPNPKMAPLGDEA 479
Query: 547 G--KRLVDTDVAR---NSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPPT 601
++++ +++ ++ DDI +H + K F +E S + T PP
Sbjct: 480 PTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAHTPEAPPPQ 539
Query: 602 LGTLRSCFSWSGGL---GDFSRTPS-----PSPSTALQQFRRKSDSPTSLPENNMSDVSQ 653
+ C GD S + P+ AL++ + T+LPE S+ +
Sbjct: 540 PPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEK-PHPHEEATTLPEEAPSNDER 598
Query: 654 LKSEESSDDESHPLREGACSSQSQESGE 681
EE+ +E PLRE + S E
Sbjct: 599 TPEEEAPPNEQRPLREEVLPKEGVASKE 626
>gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo
sapiens]
Length = 645
Score = 40.8 bits (94), Expect = 0.005
Identities = 76/328 (23%), Positives = 129/328 (39%), Gaps = 43/328 (13%)
Query: 373 RNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRPRSAEL--SEDDL 430
R+ + P+ +VS Q +E+ S V + S K +P K++ +RP + E S +
Sbjct: 212 RSKTQTPQQRSVSS--QEEEHSSPV---KAPSVKRTPMPDKTATPERPPAPENAPSSKKI 266
Query: 431 LSQYSLSFTKKT----KKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATF 486
+ + +KT K S GN + ++ PD V PT +K V+ + +
Sbjct: 267 PAPDKVPSPEKTLTLGDKASIPGNSTSG--KIPAPDKV--PTPEKMVTPEDKASIPENSI 322
Query: 487 LQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHESEYGDQE 546
+ EE+ V P T R F +S P E DK N + GD+
Sbjct: 323 IP---EETLTVDKPSTPERVFSVEES-----------PALEAPPMDKVPNPKMAPLGDEA 368
Query: 547 G--KRLVDTDVAR---NSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPPT 601
++++ +++ ++ DDI +H + K F +E S + T PP
Sbjct: 369 PTLEKVLTPELSEEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAHTPEAPPPQ 428
Query: 602 LGTLRSCFSWSGGL---GDFSRTPS-----PSPSTALQQFRRKSDSPTSLPENNMSDVSQ 653
+ C GD S + P+ AL++ + T+LPE S+ +
Sbjct: 429 PPSSERCLGEMKCTLVRGDSSPRQAELKSGPASRPALEK-PHPHEEATTLPEEAPSNDER 487
Query: 654 LKSEESSDDESHPLREGACSSQSQESGE 681
EE+ +E PLRE + S E
Sbjct: 488 TPEEEAPPNEQRPLREEVLPKEGVASKE 515
>gi|239755326 PREDICTED: hypothetical protein [Homo sapiens]
Length = 375
Score = 40.0 bits (92), Expect = 0.009
Identities = 42/168 (25%), Positives = 59/168 (35%), Gaps = 26/168 (15%)
Query: 581 TDEESYSFESSKFTRTISPPTLGTLRSCFSW------------SGGLGD--FSRTPSPSP 626
T S S++SS+ + T S + GT + +W S G +S S +
Sbjct: 151 TSSTSCSYQSSRTSSTCSCQSSGTSSTSCNWQSSRTSSTCSCQSSGTSSTSYSCQSSGTS 210
Query: 627 STALQQFRRKSDSPTSLPENNMSDVSQLKSEESSD-----DESHPLREGACSSQSQESGE 681
ST Q S + S + S +S +S S +C S S
Sbjct: 211 STCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRTSSTCSCQSSGTSSTS 270
Query: 682 FSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTSKLCLSHFSK 729
S QSS S C S + S C QS +TS C FS+
Sbjct: 271 CSCQSSGTSSTCSCQSSGTSSTSCSC-------QSSRTSSTCSCQFSR 311
Score = 36.6 bits (83), Expect = 0.10
Identities = 40/151 (26%), Positives = 52/151 (34%), Gaps = 15/151 (9%)
Query: 581 TDEESYSFESSKFTRTI---SPPTLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKS 637
T S S++ S+ + T S T T SC S S S + ST Q R S
Sbjct: 93 TSSTSCSWQFSRTSSTCCCQSSRTSSTSCSCQSSRTSSTSCSCQSSRTSSTCSCQTSRTS 152
Query: 638 DSPTSLPENNMSDVSQLKSEESSD-----DESHPLREGACSSQSQESGEFSLQSSNASKL 692
+ S + S +S +S S +C S S +S QSS S
Sbjct: 153 STSCSYQSSRTSSTCSCQSSGTSSTSCNWQSSRTSSTCSCQSSGTSSTSYSCQSSGTSST 212
Query: 693 SQCSSKDSDSEESDCNIKLLDSQSDQTSKLC 723
C S + S C QS TS C
Sbjct: 213 CSCQSSGTSSTSCSC-------QSSGTSSTC 236
Score = 35.0 bits (79), Expect = 0.29
Identities = 37/144 (25%), Positives = 56/144 (38%), Gaps = 13/144 (9%)
Query: 581 TDEESYSFESSKFTRTISPPTLGTLR-SCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDS 639
T SYS +SS + T S + GT SC S G S S+ ++ S
Sbjct: 197 TSSTSYSCQSSGTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRTS 256
Query: 640 PTSLPENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKD 699
T +++ + + + S + +C S S S QSS S S CS +
Sbjct: 257 STCSCQSSGTSSTSCSCQSSGTSSTC-----SCQSSGTSSTSCSCQSSRTS--STCSCQF 309
Query: 700 SDSEESDCNIKLLDSQSDQTSKLC 723
S + + C+ QS +TS C
Sbjct: 310 SRTSSTSCS-----CQSSRTSSTC 328
Score = 30.4 bits (67), Expect = 7.2
Identities = 24/89 (26%), Positives = 31/89 (34%), Gaps = 14/89 (15%)
Query: 635 RKSDSPTSLPENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEFSLQSSNASKLSQ 694
R S S S + S +S ++S S C S S + QSS S
Sbjct: 12 RASSSSCSCQSSQTSSTCSCQSSQTSSTCS-------CQSSGTSSTSCNWQSSRTSSTCS 64
Query: 695 CSSKDSDSEESDCNIKLLDSQSDQTSKLC 723
C S + S C QS +TS C
Sbjct: 65 CQSSGTSSTSCSC-------QSSETSSTC 86
>gi|24308334 family with sequence similarity 120B [Homo sapiens]
Length = 910
Score = 40.0 bits (92), Expect = 0.009
Identities = 62/256 (24%), Positives = 92/256 (35%), Gaps = 41/256 (16%)
Query: 1 MGIQGLLQFI-------------KEASEPIHVRKYKG--QVVAVDTYCWLHKGAIACAEK 45
MG++GL F+ KE +E H KY G + VD C L E
Sbjct: 1 MGVRGLQGFVGSTCPHICTVVNFKELAEH-HRSKYPGCTPTIVVDAMCCLRYWYTP--ES 57
Query: 46 LAKGEPTDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQ 105
G Y FV + GIK I FDG K++ RR + + +
Sbjct: 58 WICGGQWREYFSALRDFVKTFTAAGIKLIFFFDGMVEQDKRDEWVKRRLKNNREISRIFH 117
Query: 106 LLREGKVSEARECFTRSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQ 165
++ K R F I +A A ++ G + L + EAD ++A
Sbjct: 118 YIKSHKEQPGRNMFF----IPSGLAVFTRFALKTLGQETLCSLQEADYEVASYGLQHNCL 173
Query: 166 AIITEDSDLLAF--------------GCKKVILKMDQFGNGLEIDQARLGM--CRQLGDV 209
I+ ED+D L + V+L ++ L + A L + C D+
Sbjct: 174 GILGEDTDYLIYDTCPYFSISELCLESLDTVMLCREKLCESLGLCVADLPLLACLLGNDI 233
Query: 210 FTE---EKFRYMCILS 222
E E FRY C+ S
Sbjct: 234 IPEGMFESFRYKCLSS 249
>gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]
Length = 1884
Score = 39.7 bits (91), Expect = 0.012
Identities = 38/130 (29%), Positives = 55/130 (42%), Gaps = 16/130 (12%)
Query: 609 FSWSGGLGDFSRTPSPSPSTALQQ-FRRKSDSPTSLPENNMSDVSQLK----------SE 657
FS S G+ SR+PSP T L Q +RR + S EN S+ +L +
Sbjct: 1177 FSKSVQKGELSRSPSPFTHTHLAQGYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNN 1236
Query: 658 ESSDDESHPLREGACSSQSQESGEFSLQS-----SNASKLSQCSSKDSDSEESDCNIKLL 712
S H C S++ E SL++ SN L++ S + SEE+ C+ L
Sbjct: 1237 IPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLF 1296
Query: 713 DSQSDQTSKL 722
SQ + L
Sbjct: 1297 SSQCSELEDL 1306
>gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens]
Length = 1816
Score = 39.7 bits (91), Expect = 0.012
Identities = 38/130 (29%), Positives = 55/130 (42%), Gaps = 16/130 (12%)
Query: 609 FSWSGGLGDFSRTPSPSPSTALQQ-FRRKSDSPTSLPENNMSDVSQLK----------SE 657
FS S G+ SR+PSP T L Q +RR + S EN S+ +L +
Sbjct: 1130 FSKSVQKGELSRSPSPFTHTHLAQGYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNN 1189
Query: 658 ESSDDESHPLREGACSSQSQESGEFSLQS-----SNASKLSQCSSKDSDSEESDCNIKLL 712
S H C S++ E SL++ SN L++ S + SEE+ C+ L
Sbjct: 1190 IPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLF 1249
Query: 713 DSQSDQTSKL 722
SQ + L
Sbjct: 1250 SSQCSELEDL 1259
>gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]
Length = 1863
Score = 39.7 bits (91), Expect = 0.012
Identities = 38/130 (29%), Positives = 55/130 (42%), Gaps = 16/130 (12%)
Query: 609 FSWSGGLGDFSRTPSPSPSTALQQ-FRRKSDSPTSLPENNMSDVSQLK----------SE 657
FS S G+ SR+PSP T L Q +RR + S EN S+ +L +
Sbjct: 1177 FSKSVQKGELSRSPSPFTHTHLAQGYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNN 1236
Query: 658 ESSDDESHPLREGACSSQSQESGEFSLQS-----SNASKLSQCSSKDSDSEESDCNIKLL 712
S H C S++ E SL++ SN L++ S + SEE+ C+ L
Sbjct: 1237 IPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLF 1296
Query: 713 DSQSDQTSKL 722
SQ + L
Sbjct: 1297 SSQCSELEDL 1306
>gi|239744133 PREDICTED: hypothetical protein [Homo sapiens]
Length = 375
Score = 39.7 bits (91), Expect = 0.012
Identities = 42/168 (25%), Positives = 59/168 (35%), Gaps = 26/168 (15%)
Query: 581 TDEESYSFESSKFTRTISPPTLGTLRSCFSW------------SGGLGD--FSRTPSPSP 626
T S S++SS+ + T S + GT + +W S G +S S +
Sbjct: 151 TSSTSCSYQSSRTSSTCSCQSSGTSSTSCNWQSSRTSSTCSCQSSGTSSTSYSCQSSGTS 210
Query: 627 STALQQFRRKSDSPTSLPENNMSDVSQLKSEESSD-----DESHPLREGACSSQSQESGE 681
ST Q S + S + S +S +S S +C S S
Sbjct: 211 STCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRTSSTCSCQSSRTSSTS 270
Query: 682 FSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTSKLCLSHFSK 729
S QSS S C S + S C QS +TS C FS+
Sbjct: 271 CSCQSSGTSSTCSCQSSGTSSTSCSC-------QSSRTSSTCSCQFSR 311
Score = 36.6 bits (83), Expect = 0.10
Identities = 40/151 (26%), Positives = 52/151 (34%), Gaps = 15/151 (9%)
Query: 581 TDEESYSFESSKFTRTI---SPPTLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKS 637
T S S++ S+ + T S T T SC S S S + ST Q R S
Sbjct: 93 TSSTSCSWQFSRTSSTCRCQSSRTSSTSCSCQSSRTSSTSCSCQSSRTSSTCSCQTSRTS 152
Query: 638 DSPTSLPENNMSDVSQLKSEESSD-----DESHPLREGACSSQSQESGEFSLQSSNASKL 692
+ S + S +S +S S +C S S +S QSS S
Sbjct: 153 STSCSYQSSRTSSTCSCQSSGTSSTSCNWQSSRTSSTCSCQSSGTSSTSYSCQSSGTSST 212
Query: 693 SQCSSKDSDSEESDCNIKLLDSQSDQTSKLC 723
C S + S C QS TS C
Sbjct: 213 CSCQSSGTSSTSCSC-------QSSGTSSTC 236
Score = 35.8 bits (81), Expect = 0.17
Identities = 37/144 (25%), Positives = 56/144 (38%), Gaps = 13/144 (9%)
Query: 581 TDEESYSFESSKFTRTISPPTLGTLR-SCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDS 639
T SYS +SS + T S + GT SC S G S S+ ++ S
Sbjct: 197 TSSTSYSCQSSGTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRTS 256
Query: 640 PTSLPENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKD 699
T +++ + + + S + +C S S S QSS S S CS +
Sbjct: 257 STCSCQSSRTSSTSCSCQSSGTSSTC-----SCQSSGTSSTSCSCQSSRTS--STCSCQF 309
Query: 700 SDSEESDCNIKLLDSQSDQTSKLC 723
S + + C+ QS +TS C
Sbjct: 310 SRTSSTSCS-----CQSSRTSSTC 328
Score = 32.0 bits (71), Expect = 2.5
Identities = 38/153 (24%), Positives = 50/153 (32%), Gaps = 20/153 (13%)
Query: 581 TDEESYSFESSKFTRTISPPTLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSP 640
T S S +SS + T S + GT + SW S + ST Q R S +
Sbjct: 220 TSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQS---------SRTSSTCSCQSSRTSSTS 270
Query: 641 TSLPENNMSDVSQLKSEESSD-----DESHPLREGACSSQSQESGEFSLQSSNASKLSQC 695
S + S +S +S S +C S S QSS S C
Sbjct: 271 CSCQSSGTSSTCSCQSSGTSSTSCSCQSSRTSSTCSCQFSRTSSTSCSCQSSRTSSTCSC 330
Query: 696 SSKDSDSEESDCNIKLLDSQSDQTSKLCLSHFS 728
S + S C S +S C FS
Sbjct: 331 QSSGTSSTSCIC------WSSGTSSTSCSGRFS 357
Score = 30.0 bits (66), Expect = 9.4
Identities = 24/89 (26%), Positives = 31/89 (34%), Gaps = 14/89 (15%)
Query: 635 RKSDSPTSLPENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEFSLQSSNASKLSQ 694
R S S S + S +S ++S S C S S + QSS S
Sbjct: 12 RASSSSCSCQSSQTSSTCSCQSSQTSSTCS-------CQSSGTSSTSCNWQSSRISSTCS 64
Query: 695 CSSKDSDSEESDCNIKLLDSQSDQTSKLC 723
C S + S C QS +TS C
Sbjct: 65 CQSSGTSSTSCSC-------QSSETSSTC 86
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 39.7 bits (91), Expect = 0.012
Identities = 95/431 (22%), Positives = 165/431 (38%), Gaps = 69/431 (16%)
Query: 414 SSIVKRPRSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFV--PDLVNGPTNKK 471
SS KR +++E S+ S+YS ++ + ++ S ++S S+S + L + + +
Sbjct: 662 SSYHKREKNSE-SDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSR 720
Query: 472 SVSTPPRTRNKFATFLQ--RKNEESGAVVVPGTRS-RFFCSSDSTDCVSNK----VSIQP 524
S S+ +RNK++ Q R + + G R+ R SS + VS+K S +
Sbjct: 721 SPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKT 780
Query: 525 LDETAVTDKENNLHESEYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEE 584
L V ++ + +Y + +D ++S + + T E+
Sbjct: 781 LHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEK 840
Query: 585 SYSFESSKFTRTISPPTLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLP 644
+ E SK R TL+ L D R S + S+S
Sbjct: 841 NRGEEKSKSERECPHSKKRTLKE------NLSDHLRNGSKPKRKNYAGSKWDSES----- 889
Query: 645 ENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEE 704
N+ DV+ ++S ++SHP S +E GE ++ DS+SE
Sbjct: 890 -NSERDVT-----KNSKNDSHP-------SSDKEEGE--------------ATSDSESEV 922
Query: 705 SDCNIKLLDSQSDQTSKLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARAS 764
S+ +IK+ + T+ P N G +KSS + ++ S
Sbjct: 923 SEIHIKVKPTTKSSTN---------TSLPDDN---GAWKSSKQRTSTSD-----SEGSCS 965
Query: 765 GLSKKPASIQKRKHHNAEN-KPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQL 823
QK KH + EN K K+ E K KKD + P +K + ++
Sbjct: 966 NSENNRGKPQKHKHGSKENLKREHTKKVKEKLKG---KKDKKHKAPKRKQAFHWQPPLEF 1022
Query: 824 TPEAEEDIFNK 834
E EE+I +K
Sbjct: 1023 GEEEEEEIDDK 1033
>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
sapiens]
Length = 1082
Score = 39.3 bits (90), Expect = 0.016
Identities = 27/127 (21%), Positives = 53/127 (41%), Gaps = 2/127 (1%)
Query: 636 KSDSPTSLPENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEFSLQSSNASKLSQC 695
+S+S + + S S +S+ DE G+ S QS+E G+ + + +
Sbjct: 698 ESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEA 757
Query: 696 SSKDSDSEESDCNIKLLDSQSDQTSKLCLSHFSKKDTPLRNKVPGLYKSSSAD--SLSTT 753
SS D S+ S + + + + +L + +S+K P P + S D +
Sbjct: 758 SSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSKSAPATKEISLLDLEDFTPP 817
Query: 754 KIKPLGP 760
++P+ P
Sbjct: 818 SVQPVSP 824
>gi|153792780 additional sex combs like 2 [Homo sapiens]
Length = 1435
Score = 38.9 bits (89), Expect = 0.020
Identities = 62/254 (24%), Positives = 108/254 (42%), Gaps = 46/254 (18%)
Query: 607 SCFSWSGGLG-DFSRTPSPSPSTALQQFRRKSDSPTSLPENNMS------DVSQLKSEES 659
S + S GL + S+ + SPS + + ++ P S+P + S VSQ + +E
Sbjct: 376 SYYGQSSGLSLEDSKKLTASPSDPKVK-KTPAEQPKSMPVSEASLIRIVPVVSQSECKEE 434
Query: 660 SDDESHPLREGACSSQSQESGEFSLQS----SNASKLSQCSS-------KDSDSEESDCN 708
+ S P R+ C SQ + FS S S+A + SS KD D E
Sbjct: 435 ALQMSSPGRKEECESQGEVQPNFSTSSEPLLSSALNTHELSSILPIKCPKDEDLLEQK-P 493
Query: 709 IKLLDSQSDQTSKLCLSHFSKKD-------TPLRNKVPGLYK-----SSSADSLSTTKIK 756
+ + +S++ S+++K + +P + K PG+ K ++ A T +
Sbjct: 494 VTSAEQESEKNHLTTASNYNKSESQESLVTSPSKPKSPGVEKPIVKPTAGAGPQETNMKE 553
Query: 757 PLGP---------ARASGLSKK--PASIQKRKH--HNAENKPGLQIKLNELWKNFGFKKD 803
PL R S L+++ P S +KR N +++ Q+ + + N G +
Sbjct: 554 PLATLVDQSPESLKRKSSLTQEEAPVSWEKRPRVTENRQHQQPFQVS-PQPFLNRGDRIQ 612
Query: 804 SEKLPPCKKPLSPV 817
K+PP K P+S +
Sbjct: 613 VRKVPPLKIPVSRI 626
>gi|223029510 echinoderm microtubule associated protein like 4
isoform b [Homo sapiens]
Length = 923
Score = 38.5 bits (88), Expect = 0.026
Identities = 29/77 (37%), Positives = 40/77 (51%), Gaps = 12/77 (15%)
Query: 619 SRTPSPSPSTAL----QQFRRKSDSPTSLPENNMS-------DVSQLKSEESSDDESHPL 667
S TP+P PS L ++ R S SPT L EN++ D S+ +SEE S D PL
Sbjct: 837 SNTPTPPPSQPLNETAEEESRISSSPTLL-ENSLEQTVEPSEDHSEEESEEGSGDLGEPL 895
Query: 668 REGACSSQSQESGEFSL 684
E C+ S+E + +L
Sbjct: 896 YEEPCNEISKEQAKATL 912
>gi|19923497 echinoderm microtubule associated protein like 4
isoform a [Homo sapiens]
Length = 981
Score = 38.5 bits (88), Expect = 0.026
Identities = 29/77 (37%), Positives = 40/77 (51%), Gaps = 12/77 (15%)
Query: 619 SRTPSPSPSTAL----QQFRRKSDSPTSLPENNMS-------DVSQLKSEESSDDESHPL 667
S TP+P PS L ++ R S SPT L EN++ D S+ +SEE S D PL
Sbjct: 895 SNTPTPPPSQPLNETAEEESRISSSPTLL-ENSLEQTVEPSEDHSEEESEEGSGDLGEPL 953
Query: 668 REGACSSQSQESGEFSL 684
E C+ S+E + +L
Sbjct: 954 YEEPCNEISKEQAKATL 970
>gi|157384986 transducin-like enhancer protein 3 isoform b [Homo
sapiens]
Length = 769
Score = 38.5 bits (88), Expect = 0.026
Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 16/147 (10%)
Query: 645 ENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEFSLQSSN--ASKLSQCSSKDSDS 702
E N ++ + E S+++ P S + + S ++S+++ A + S DSD
Sbjct: 183 EKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDG 242
Query: 703 EESDCNIKLLDSQSDQTSKLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPAR 762
++SD + + ++ T ++ +H +P N GL K+ S K P PA
Sbjct: 243 DKSDDLVVDVSNEDPATPRVSPAH-----SPPEN---GLDKARSLK-----KDAPTSPAS 289
Query: 763 ASGLSKKPASIQKRKHHNAENK-PGLQ 788
+ S P+S K HN ++ PGL+
Sbjct: 290 VASSSSTPSSKTKDLGHNDKSSTPGLK 316
>gi|157384984 transducin-like enhancer protein 3 isoform c [Homo
sapiens]
Length = 760
Score = 38.5 bits (88), Expect = 0.026
Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 16/147 (10%)
Query: 645 ENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEFSLQSSN--ASKLSQCSSKDSDS 702
E N ++ + E S+++ P S + + S ++S+++ A + S DSD
Sbjct: 183 EKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDG 242
Query: 703 EESDCNIKLLDSQSDQTSKLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPAR 762
++SD + + ++ T ++ +H +P N GL K+ S K P PA
Sbjct: 243 DKSDDLVVDVSNEDPATPRVSPAH-----SPPEN---GLDKARSLK-----KDAPTSPAS 289
Query: 763 ASGLSKKPASIQKRKHHNAENK-PGLQ 788
+ S P+S K HN ++ PGL+
Sbjct: 290 VASSSSTPSSKTKDLGHNDKSSTPGLK 316
>gi|157384982 transducin-like enhancer protein 3 isoform a [Homo
sapiens]
Length = 772
Score = 38.5 bits (88), Expect = 0.026
Identities = 36/147 (24%), Positives = 66/147 (44%), Gaps = 16/147 (10%)
Query: 645 ENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEFSLQSSN--ASKLSQCSSKDSDS 702
E N ++ + E S+++ P S + + S ++S+++ A + S DSD
Sbjct: 183 EKNHHELDHRERESSANNSVSPSESLRASEKHRGSADYSMEAKKRKAEEKDSLSRYDSDG 242
Query: 703 EESDCNIKLLDSQSDQTSKLCLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPAR 762
++SD + + ++ T ++ +H +P N GL K+ S K P PA
Sbjct: 243 DKSDDLVVDVSNEDPATPRVSPAH-----SPPEN---GLDKARSLK-----KDAPTSPAS 289
Query: 763 ASGLSKKPASIQKRKHHNAENK-PGLQ 788
+ S P+S K HN ++ PGL+
Sbjct: 290 VASSSSTPSSKTKDLGHNDKSSTPGLK 316
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,725,443
Number of Sequences: 37866
Number of extensions: 1553229
Number of successful extensions: 4921
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 162
Number of HSP's that attempted gapping in prelim test: 4517
Number of HSP's gapped (non-prelim): 431
length of query: 846
length of database: 18,247,518
effective HSP length: 111
effective length of query: 735
effective length of database: 14,044,392
effective search space: 10322628120
effective search space used: 10322628120
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.