BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|39930511 collagen and calcium binding EGF domains 1 [Homo sapiens] (406 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|39930511 collagen and calcium binding EGF domains 1 [Homo sap... 879 0.0 gi|11386161 alpha 2 type IX collagen [Homo sapiens] 102 5e-22 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 101 1e-21 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 101 1e-21 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 101 1e-21 gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 101 1e-21 gi|38570075 collagen, type XXV, alpha 1 isoform 1 [Homo sapiens] 101 1e-21 gi|38570073 collagen, type XXV, alpha 1 isoform 2 [Homo sapiens] 101 1e-21 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 100 4e-21 gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 99 7e-21 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 99 7e-21 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 99 9e-21 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 97 2e-20 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 97 2e-20 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 97 2e-20 gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 97 2e-20 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 97 2e-20 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 97 3e-20 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 97 3e-20 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 97 3e-20 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 97 3e-20 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 97 3e-20 gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 97 3e-20 gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 97 3e-20 gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens] 96 4e-20 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 96 6e-20 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 96 6e-20 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 96 8e-20 gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 96 8e-20 gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 96 8e-20 >gi|39930511 collagen and calcium binding EGF domains 1 [Homo sapiens] Length = 406 Score = 879 bits (2271), Expect = 0.0 Identities = 406/406 (100%), Positives = 406/406 (100%) Query: 1 MVPPPPSRGGAARGQLGRSLGPLLLLLALGHTWTYREEPEDGDREICSESKIATTKYPCL 60 MVPPPPSRGGAARGQLGRSLGPLLLLLALGHTWTYREEPEDGDREICSESKIATTKYPCL Sbjct: 1 MVPPPPSRGGAARGQLGRSLGPLLLLLALGHTWTYREEPEDGDREICSESKIATTKYPCL 60 Query: 61 KSSGELTTCYRKKCCKGYKFVLGQCIPEDYDVCAEAPCEQQCTDNFGRVLCTCYPGYRYD 120 KSSGELTTCYRKKCCKGYKFVLGQCIPEDYDVCAEAPCEQQCTDNFGRVLCTCYPGYRYD Sbjct: 61 KSSGELTTCYRKKCCKGYKFVLGQCIPEDYDVCAEAPCEQQCTDNFGRVLCTCYPGYRYD 120 Query: 121 RERHRKREKPYCLDIDECASSNGTLCAHICINTLGSYRCECREGYIREDDGKTCTRGDKY 180 RERHRKREKPYCLDIDECASSNGTLCAHICINTLGSYRCECREGYIREDDGKTCTRGDKY Sbjct: 121 RERHRKREKPYCLDIDECASSNGTLCAHICINTLGSYRCECREGYIREDDGKTCTRGDKY 180 Query: 181 PNDTGHEKSENMVKAGTCCATCKEFYQMKQTVLQLKQKIALLPNNAADLGKYITGDKVLA 240 PNDTGHEKSENMVKAGTCCATCKEFYQMKQTVLQLKQKIALLPNNAADLGKYITGDKVLA Sbjct: 181 PNDTGHEKSENMVKAGTCCATCKEFYQMKQTVLQLKQKIALLPNNAADLGKYITGDKVLA 240 Query: 241 SNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300 SNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG Sbjct: 241 SNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQEKVFGHR 360 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQEKVFGHR Sbjct: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQEKVFGHR 360 Query: 361 THSSAEEFPLPQEFPSYPEAMDLGSGDDHPRRTETRDLRAPRDFYP 406 THSSAEEFPLPQEFPSYPEAMDLGSGDDHPRRTETRDLRAPRDFYP Sbjct: 361 THSSAEEFPLPQEFPSYPEAMDLGSGDDHPRRTETRDLRAPRDFYP 406 >gi|11386161 alpha 2 type IX collagen [Homo sapiens] Length = 689 Score = 102 bits (255), Expect = 5e-22 Identities = 49/89 (55%), Positives = 54/89 (60%), Gaps = 2/89 (2%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 +PG PG GG G G PGP+G PGF G PG G+PGPRG +GP G QG RGP Sbjct: 338 VPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKG--DQGERGP 395 Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 VG PG GR G KGE+G PG G G PG Sbjct: 396 VGQPGPQGRQGPKGEQGPPGIPGPQGLPG 424 Score = 92.8 bits (229), Expect = 5e-19 Identities = 46/96 (47%), Positives = 51/96 (53%), Gaps = 8/96 (8%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG PG QGP G PGP+G PG G G G GP+G G G ++ G GP Sbjct: 561 PGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPP 620 Query: 306 GPPGAPGR--------DGSKGERGAPGPRGSPGPPG 333 G PG PGR DG +G GAPG G PG PG Sbjct: 621 GIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPG 656 Score = 85.1 bits (209), Expect = 1e-16 Identities = 46/90 (51%), Positives = 49/90 (54%), Gaps = 15/90 (16%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGF---PGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303 G PG+ G G G PGP G PG PG+PGPPG PGP G GP GP G Sbjct: 78 GKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPP-----------G 125 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 PVG PG G G KG+ G GP G PGPPG Sbjct: 126 PVGLPGEIGIRGPKGDPGPDGPSGPPGPPG 155 Score = 83.6 bits (205), Expect = 3e-16 Identities = 44/93 (47%), Positives = 53/93 (56%), Gaps = 9/93 (9%) Query: 246 PGPPGLPGG---QGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PDLSHIKQG 300 PGP G G QGPPG PGP+G PG G G PG+ GPRG +G G + P ++G Sbjct: 399 PGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPG----EKG 454 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G G PG G+ G +GE G PGP G G PG Sbjct: 455 EKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPG 487 Score = 83.2 bits (204), Expect = 4e-16 Identities = 46/98 (46%), Positives = 52/98 (53%), Gaps = 4/98 (4%) Query: 238 VLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGP-SPD 293 V+ + + GPPG G GPPG PG GS G G GPPG+ PGP+G G GP PD Sbjct: 18 VVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPD 77 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGP 331 G G G PG G G KG+ G PGP G PGP Sbjct: 78 GKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP 115 Score = 83.2 bits (204), Expect = 4e-16 Identities = 53/125 (42%), Positives = 60/125 (48%), Gaps = 37/125 (29%) Query: 245 LPGPPGLPGG--QGPPGSPGP------------KGSPGFPGMPGPPGQPGPRGSMGPM-- 288 LPGPPGLPG GPPG PGP KG PG G GPPG PG G G + Sbjct: 106 LPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQG 165 Query: 289 ------------------GPSPDLSHIK--QGRRGPVGPPGAPGRDGSKGERGAPGPRGS 328 GP P L +K G+RG +G PG G+ G KG+ GA G +G Sbjct: 166 LEGSADFLCPTNCPPGMKGP-PGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGI 224 Query: 329 PGPPG 333 PGPPG Sbjct: 225 PGPPG 229 Score = 82.8 bits (203), Expect = 5e-16 Identities = 45/93 (48%), Positives = 50/93 (53%), Gaps = 6/93 (6%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLSHI--KQGRR 302 GPPG PG G PGS G G G PG GPPG G G GP GP P + + +G Sbjct: 33 GPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEP 92 Query: 303 GPVGPPGAPGRDGSKGERGAPGP--RGSPGPPG 333 GP+G PG G+ G G G PGP G PGPPG Sbjct: 93 GPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPG 125 Score = 82.8 bits (203), Expect = 5e-16 Identities = 49/113 (43%), Positives = 58/113 (51%), Gaps = 10/113 (8%) Query: 231 KYITGDKVLASNTYLPGPPGLPG--GQ-GPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGP 287 K TG + PG PG+ G GQ G PGSPG +G G PG PG G PG +G GP Sbjct: 297 KGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGP 356 Query: 288 MG----PSPDLSHIKQGRRGPVGPPGAPGRDGSKGER---GAPGPRGSPGPPG 333 G P + G RG +GP G G+ G +GER G PGP+G GP G Sbjct: 357 QGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKG 409 Score = 82.4 bits (202), Expect = 7e-16 Identities = 45/100 (45%), Positives = 53/100 (53%), Gaps = 17/100 (17%) Query: 246 PGPPG---LPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 PGP G G QG PG PGP+G G+PGM GP G+ GP G G +G G Sbjct: 210 PGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIG-----ATGPP 264 Query: 303 GPVGPPGAPGRDGSKGERGAP---------GPRGSPGPPG 333 G GP G PGR G KG+ G+P GP+G+ GPPG Sbjct: 265 GEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPG 304 Score = 82.4 bits (202), Expect = 7e-16 Identities = 45/106 (42%), Positives = 55/106 (51%), Gaps = 19/106 (17%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-----PSPDLSHIK--- 298 GPPG G +GPPG G KG G PG+ GP G GP+G+ GP G +P +K Sbjct: 262 GPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSA 321 Query: 299 --------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSP---GPPG 333 G +G G PG PG G G++G PGP+G P GPPG Sbjct: 322 GQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPG 367 Score = 81.6 bits (200), Expect = 1e-15 Identities = 42/92 (45%), Positives = 51/92 (55%), Gaps = 14/92 (15%) Query: 245 LPGPPGLPGGQGPPGSP---GPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301 +PGP GLPG +G GSP GP+G G PG+ G PG+ G +G G GP Sbjct: 416 IPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGP----------- 464 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G G G PG G G+ GAPG +G PGPPG Sbjct: 465 KGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPG 496 Score = 79.7 bits (195), Expect = 4e-15 Identities = 47/96 (48%), Positives = 49/96 (51%), Gaps = 20/96 (20%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GP G PG P G GPKG G PG+PGP G PG +G G G K G RG VG Sbjct: 394 GPVGQPG---PQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPG--------KTGPRGKVG 442 Query: 307 PPGA---PGRDGSKGERGAPGP------RGSPGPPG 333 PG PG G KGE G PGP RG PG PG Sbjct: 443 DPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPG 478 Score = 78.6 bits (192), Expect = 1e-14 Identities = 49/139 (35%), Positives = 56/139 (40%), Gaps = 37/139 (26%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRG--------- 283 + G+K + PGP G G +G PG PGP G G PG+ G PG PGPRG Sbjct: 449 LPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPG 508 Query: 284 ---SMGPMGPSPDLSHIKQ-------------------------GRRGPVGPPGAPGRDG 315 G G HI G GP GPPG PG G Sbjct: 509 QPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPG 568 Query: 316 SKGERGAPGPRGSPGPPGS 334 +G G PGPRG PG G+ Sbjct: 569 KQGPHGHPGPRGVPGIVGA 587 Score = 76.3 bits (186), Expect = 5e-14 Identities = 46/116 (39%), Positives = 55/116 (47%), Gaps = 16/116 (13%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQPGPRGSMGPMGP- 290 GD + +PGPPG G +G PG GPKG G + GM G G GP G GP GP Sbjct: 214 GDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPP 273 Query: 291 ----------SPDLSHIK--QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 SP + + G +G GPPG G+DG+ G G G G G PGS Sbjct: 274 GRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGS 329 Score = 67.4 bits (163), Expect = 2e-11 Identities = 43/101 (42%), Positives = 44/101 (43%), Gaps = 14/101 (13%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292 + GDK T G G PG G PG G KG G PGP GQ G RG G GPS Sbjct: 425 VKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGE---SGEPGPKGQQGVRGEPGYPGPS- 480 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G PG G G G RG G RG PG PG Sbjct: 481 ----------GDAGAPGVQGYPGPPGPRGLAGNRGVPGQPG 511 Score = 58.9 bits (141), Expect = 8e-09 Identities = 37/94 (39%), Positives = 39/94 (41%), Gaps = 32/94 (34%) Query: 255 QGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPP------ 308 +GPPG GP PG PGPPG PG G G GP G GPP Sbjct: 26 RGPPGERGP------PGPPGPPGVPGSDGIDGDNGPP-----------GKAGPPGPKGEP 68 Query: 309 ---------GAPGRDGSKGERGAPGPRGSPGPPG 333 G PG DG G +G PGP G PG G Sbjct: 69 GKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKG 102 Score = 52.4 bits (124), Expect = 7e-07 Identities = 26/52 (50%), Positives = 30/52 (57%), Gaps = 5/52 (9%) Query: 245 LPGPPGLPGGQGPPGSP-----GPKGSPGFPGMPGPPGQPGPRGSMGPMGPS 291 +PGPPG+PG G PG G +GSPG PG G PG PGP G G P+ Sbjct: 616 MPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPA 667 Score = 33.9 bits (76), Expect = 0.27 Identities = 14/20 (70%), Positives = 14/20 (70%) Query: 315 GSKGERGAPGPRGSPGPPGS 334 G GERG PGP G PG PGS Sbjct: 27 GPPGERGPPGPPGPPGVPGS 46 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 101 bits (252), Expect = 1e-21 Identities = 55/101 (54%), Positives = 61/101 (60%), Gaps = 15/101 (14%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSM------GPMGPSP 292 LPGPPG PG G G+ GPKG GFPG PGPPG+ PGP+G + GPMGP P Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP-P 813 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 L I G +GP GPPG PG G G G PG +G PGPPG Sbjct: 814 GLPGI--GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG 852 Score = 101 bits (251), Expect = 1e-21 Identities = 52/102 (50%), Positives = 60/102 (58%), Gaps = 19/102 (18%) Query: 246 PGPPGLPGGQGPPGS------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299 PGPPG+PG +G PGS PGPKG+PG+PG PG G PGP G GP+GP Sbjct: 146 PGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG-----PP 200 Query: 300 GRRGPVGPPGAPGRDGS--------KGERGAPGPRGSPGPPG 333 G GP GPPG PG G+ KGE+G G +G PGPPG Sbjct: 201 GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG 242 Score = 98.6 bits (244), Expect = 9e-21 Identities = 58/113 (51%), Positives = 63/113 (55%), Gaps = 26/113 (23%) Query: 246 PGPPGLPG--GQ----------GPPGSPGPKGSP---GFPGMPGPPGQP--------GPR 282 PGPPGLPG GQ G PG PGPKG P GFPG+ GPPG P GP+ Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251 Query: 283 GSMGPMGP--SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G+ GP GP P + QG GP GPPG PG G KGE+G PG G PG PG Sbjct: 1252 GNPGPQGPPGRPGPTGF-QGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1303 Score = 97.8 bits (242), Expect = 2e-20 Identities = 50/102 (49%), Positives = 59/102 (57%), Gaps = 10/102 (9%) Query: 242 NTYLPGPPGLPGGQGPPGSPGPKGSPGFPGM---PGPPGQPGPRGSMGPMGPSPDLSHIK 298 N PGPPG+ G GP G PGP G PG PG+ PGPPG PGP+G+MG P + Sbjct: 172 NPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGE 231 Query: 299 QGRRGPVGPPGAPGR-------DGSKGERGAPGPRGSPGPPG 333 QG +GP GPPG + KG++G PG RG PGPPG Sbjct: 232 QGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273 Score = 94.4 bits (233), Expect = 2e-19 Identities = 49/94 (52%), Positives = 55/94 (58%), Gaps = 11/94 (11%) Query: 246 PGPPGL------PGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299 PG PG+ PG G PG+PG KG PG PG PG PG PGP+G GP G +P L Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG-NPGL----P 1145 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GPVG G PG+ G GE+G PG G PGP G Sbjct: 1146 GEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179 Score = 93.6 bits (231), Expect = 3e-19 Identities = 58/117 (49%), Positives = 61/117 (52%), Gaps = 22/117 (18%) Query: 235 GDKVLASNTYLPGPPGLPG-----------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRG 283 GD L + LPG PGLPG G G PG PGPKG PG PG PG PG PG G Sbjct: 675 GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIG 734 Query: 284 SMGPMGPSPDLSHIKQ----GRRGPVGPPGAPGRDGS---KGERGAPGPRGSPGPPG 333 GP GP P K GP GPPG PG G+ KG+RG PGP PGPPG Sbjct: 735 LEGPPGP-PGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGP---PGPPG 787 Score = 93.6 bits (231), Expect = 3e-19 Identities = 48/100 (48%), Positives = 56/100 (56%), Gaps = 12/100 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGP 304 PG PGL G G PG PGPKG+PG PG PG G PG +G++G MG P P G G Sbjct: 990 PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049 Query: 305 VGPPGAPGRDGSKGER-----------GAPGPRGSPGPPG 333 G PG+PG G KG++ G PGP+G PG PG Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPG 1089 Score = 93.2 bits (230), Expect = 4e-19 Identities = 52/101 (51%), Positives = 56/101 (55%), Gaps = 14/101 (13%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGS-----MGPMGPSPDLSHIK-- 298 PGP G PG GPPG+PG G G G PGPPG PGP+G GP GP P L K Sbjct: 712 PGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGP-PGLPGFKGA 770 Query: 299 ---QGRRGPVGPPGAPGR---DGSKGERGAPGPRGSPGPPG 333 +G RG GPPG PGR DG G +G GP G PGP G Sbjct: 771 LGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMG 811 Score = 92.4 bits (228), Expect = 6e-19 Identities = 54/116 (46%), Positives = 57/116 (49%), Gaps = 7/116 (6%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPG-----GQGPPGSPGPKGSPGFPGMPGPPG 277 P D+G + GD L LPG PG G G G PG PGPKG PG PG PG PG Sbjct: 671 PGRDGDVG--LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPG 728 Query: 278 QPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 PG G GP GP + GPPG PG G KG G G RG PGPPG Sbjct: 729 TPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPG 784 Score = 91.7 bits (226), Expect = 1e-18 Identities = 48/96 (50%), Positives = 56/96 (58%), Gaps = 7/96 (7%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRG 303 +PGPPG G +GPPG PG G+PG PGMPG G PGP+G G G + G G Sbjct: 82 IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141 Query: 304 PVGPPGAPGRDGSKGERGA------PGPRGSPGPPG 333 GPPG PG G KGE G+ PGP+G+PG PG Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG 177 Score = 90.5 bits (223), Expect = 2e-18 Identities = 48/98 (48%), Positives = 52/98 (53%), Gaps = 11/98 (11%) Query: 247 GPPGLPG-----GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301 GPPGLPG GPPG PGP G PG G+PG G PGP G P P S G Sbjct: 811 GPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGA 870 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGS------PGPPG 333 GP+GPPG+PG G G G PG +G PGPPG Sbjct: 871 PGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908 Score = 90.5 bits (223), Expect = 2e-18 Identities = 45/91 (49%), Positives = 50/91 (54%), Gaps = 3/91 (3%) Query: 246 PGPPGL---PGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 PGP G+ PG G PG PGP G G PG PGPPG+ G G G GP+ Q Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GPPG PG G KG+ G PG G+PG PG Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPG 1220 Score = 89.0 bits (219), Expect = 7e-18 Identities = 52/109 (47%), Positives = 60/109 (55%), Gaps = 9/109 (8%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--P 290 I G+K L G PGLPG GP G PGP+G G G+PGPPG G RG G G Sbjct: 43 IKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPG 102 Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPG 333 +P L + G G GP G PG +G+KGERG PG +G PGPPG Sbjct: 103 TPGLPGM-PGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150 Score = 89.0 bits (219), Expect = 7e-18 Identities = 54/116 (46%), Positives = 63/116 (54%), Gaps = 19/116 (16%) Query: 235 GDKVLASNTYLPGPPGL-------------PGGQGPPGSPGPKGSPGFPGMPGPPGQPGP 281 G+K +T PGPPGL G G PG PG KG GFPG+ GPPG PGP Sbjct: 328 GEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP 387 Query: 282 RGS--MGPMGPSPDLSHIKQGRRGPVGPPG--APGRDGSKGERGAPGPRGSPGPPG 333 G+ MGP GP P ++G++G GPPG PG G G+ GAPG G PGP G Sbjct: 388 PGAAVMGPPGP-PGFPG-ERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAG 441 Score = 88.6 bits (218), Expect = 9e-18 Identities = 50/107 (46%), Positives = 58/107 (54%), Gaps = 12/107 (11%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGPS--------PD 293 +PGPPG G G PG+PGP G PG PG+PG G PG +G MG MGP P Sbjct: 855 VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG 914 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLL 340 S + G +G G G PG G GE+G+ G G PGPPG D LL Sbjct: 915 RSGV-PGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960 Score = 88.2 bits (217), Expect = 1e-17 Identities = 57/135 (42%), Positives = 62/135 (45%), Gaps = 28/135 (20%) Query: 222 LPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPP---------------GSPGPKGS 266 LP N I G+K LPG PGL G QGPP G PG G Sbjct: 1280 LPGNGG-----IKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGV 1334 Query: 267 PGFPGMPGP---PGQPGPRGSMGPMGPS-----PDLSHIKQGRRGPVGPPGAPGRDGSKG 318 PGFPGM GP PG GP G G +GP P S +G GPPG PG+ G KG Sbjct: 1335 PGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKG 1394 Query: 319 ERGAPGPRGSPGPPG 333 G GP+G PGP G Sbjct: 1395 LPGPQGPQGLPGPTG 1409 Score = 87.4 bits (215), Expect = 2e-17 Identities = 49/120 (40%), Positives = 58/120 (48%), Gaps = 20/120 (16%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPP--GSPGPKGSP---------GFPGMPGPPGQPGPRG 283 G+K +PGP G G G P G+PGP G P G PG+PG PG PGP+G Sbjct: 1164 GEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG 1223 Query: 284 S---------MGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 GP GP +G +G GP G PGR G G +G PGP G PG PG+ Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGN 1283 Score = 87.0 bits (214), Expect = 3e-17 Identities = 44/94 (46%), Positives = 52/94 (55%), Gaps = 7/94 (7%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL------SHIKQG 300 G PG G G PG PG G PG+PG PG G+ G +G GP GP P L + I G Sbjct: 298 GKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGP-PGLVIPRPGTGITIG 356 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 +G +G PG PG G +G G GP G PGPPG+ Sbjct: 357 EKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGA 390 Score = 85.9 bits (211), Expect = 6e-17 Identities = 48/92 (52%), Positives = 53/92 (57%), Gaps = 12/92 (13%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQ---PGPRGSMGPMGPSPDLSHIK 298 LPG PG PG G PG PGPKG PG F G GPPG PG G++GPMGP P Sbjct: 571 LPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGP-PGF---- 625 Query: 299 QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPG 330 G GPVG G G G+ G+ G PGP+G PG Sbjct: 626 -GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656 Score = 85.5 bits (210), Expect = 8e-17 Identities = 49/117 (41%), Positives = 56/117 (47%), Gaps = 27/117 (23%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPG----------FPGMPGPPGQPGPRGSMGPMGPSPD- 293 +PGPPGL G G PG PGP G G PG PGPPG PG +G G G D Sbjct: 418 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDK 477 Query: 294 ----LSHIKQGRRGPVGPPGA------------PGRDGSKGERGAPGPRGSPGPPGS 334 + I G GP G PG PG+ G KG+ GA GP+G PG PG+ Sbjct: 478 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGA 534 Score = 85.5 bits (210), Expect = 8e-17 Identities = 48/102 (47%), Positives = 53/102 (51%), Gaps = 9/102 (8%) Query: 242 NTYLPGPPGLPGGQGPPGSPGP---KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIK 298 N LPG PG GG G PG PGP KG PG G+PGP GQ G G G P P Sbjct: 1141 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1200 Query: 299 QGRRGPVGPPGAPGRDGSKGERGA------PGPRGSPGPPGS 334 G++G G PG PG G G +G PG +G PGPPGS Sbjct: 1201 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS 1242 Score = 84.7 bits (208), Expect = 1e-16 Identities = 47/107 (43%), Positives = 52/107 (48%), Gaps = 16/107 (14%) Query: 246 PGPPGLPGGQGPPGS---------------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGP 290 PG PGLPG GPPGS GPKG PG PG PG PG PG +G G + Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552 Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 P + K G G G PG PG G+ G+ G PG G G PG F Sbjct: 553 FPGMKGDK-GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITF 598 Score = 84.7 bits (208), Expect = 1e-16 Identities = 50/96 (52%), Positives = 53/96 (55%), Gaps = 8/96 (8%) Query: 243 TYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 T L G PG G GP G PGP G PG PG+ G G PGP G GP+G P L H G + Sbjct: 789 TGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIPGPIG-QPGL-HGIPGEK 845 Query: 303 GPVGP-----PGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP PG PG GS G GAPGP G PG PG Sbjct: 846 GDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881 Score = 84.3 bits (207), Expect = 2e-16 Identities = 52/111 (46%), Positives = 57/111 (51%), Gaps = 12/111 (10%) Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGS----PGPK------GSPGFPGMPGPPGQPGPRG 283 TG K L PG PG PG +G PG PG K GSPG PG+PG PG PG G Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582 Query: 284 SMGPMGPSPDLSHIK-QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP + I +G RGP G PG PG G+ G G PG G PGP G Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVG 632 Score = 84.3 bits (207), Expect = 2e-16 Identities = 56/135 (41%), Positives = 65/135 (48%), Gaps = 22/135 (16%) Query: 222 LPNNAADLGKYIT--------GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMP 273 +P D G+ IT G+ + LPG PGLPG G PG PG KG PG PG+ Sbjct: 648 IPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI- 706 Query: 274 GPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERG-----------A 322 G PG PGP+G G P P + GR G GPPG PG G KGE G Sbjct: 707 GLPGPPGPKGFPGI--PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL 764 Query: 323 PGPRGSPGPPGSFDF 337 PG +G+ GP G F Sbjct: 765 PGFKGALGPKGDRGF 779 Score = 84.0 bits (206), Expect = 2e-16 Identities = 46/95 (48%), Positives = 53/95 (55%), Gaps = 13/95 (13%) Query: 246 PGPPGLPGGQGPPGSPG---PKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 PG PG G GPPG PG KG G PG+PG PG PGP+G G H G + Sbjct: 1184 PGQPGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPG--------FHGFPGVQ 1234 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 GP GPPG+PG +G +G PGP+G PG PG F Sbjct: 1235 GPPGPPGSPG-PALEGPKGNPGPQGPPGRPGPTGF 1268 Score = 83.2 bits (204), Expect = 4e-16 Identities = 48/100 (48%), Positives = 52/100 (52%), Gaps = 16/100 (16%) Query: 246 PGPPGLPG--GQ--------GPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PD 293 PGPPGLPG GQ GPPG PG G G PG GP G PGP G G G + P Sbjct: 1362 PGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPG 1421 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G G PG PG+ G++G G PGP G GPPG Sbjct: 1422 F----DGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG 1457 Score = 82.8 bits (203), Expect = 5e-16 Identities = 49/103 (47%), Positives = 53/103 (51%), Gaps = 13/103 (12%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-----PDLSHIK- 298 L GP G PG QGPPG PGP G G PG GPPG PG G G G P L +K Sbjct: 1247 LEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKG 1306 Query: 299 -QGRRGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPGS 334 QG G G PG PG +G KG+ G PG +G G PGS Sbjct: 1307 DQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS 1349 Score = 82.8 bits (203), Expect = 5e-16 Identities = 42/88 (47%), Positives = 47/88 (53%), Gaps = 8/88 (9%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GPPG+PG G G PGP+G G PG GPPG PG G G G GR+G G Sbjct: 1382 GPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAG--------GRKGDPG 1433 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGS 334 PG PG G G G G +G PGPPG+ Sbjct: 1434 LPGQPGTRGLDGPPGPDGLQGPPGPPGT 1461 Score = 82.4 bits (202), Expect = 7e-16 Identities = 49/115 (42%), Positives = 53/115 (46%), Gaps = 14/115 (12%) Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGP------------KGSPGFPGMPGPPGQ 278 K I G L PG PG+PG G PG G GSPGFPG+ GPPG Sbjct: 89 KGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGP 148 Query: 279 PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 PG G G P + G +G G PG PG G G G PGP G PGPPG Sbjct: 149 PGIPGMKGE--PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201 Score = 82.4 bits (202), Expect = 7e-16 Identities = 49/110 (44%), Positives = 56/110 (50%), Gaps = 22/110 (20%) Query: 246 PGPPG---LPGGQGPPGSPGP---KGSPGFPGMPGPPGQPGPRGSMGPMG-----PSPDL 294 PGP G LPG +GPPG PG KG G PG PG PG PG +G GP G P L Sbjct: 1263 PGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGL 1322 Query: 295 SHIK-----------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 + +K G +GP G PG+ G +G G G PGP G PGP G Sbjct: 1323 NGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG 1372 Score = 82.0 bits (201), Expect = 9e-16 Identities = 47/97 (48%), Positives = 49/97 (50%), Gaps = 9/97 (9%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG---PMGPSPDLSHIKQGRR 302 PG PG PG G G PG G PG PG+PG PG G G G P P P +G Sbjct: 665 PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGP------KGFP 718 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLL 339 G GPPGAPG G G G PGP G PGP G F L Sbjct: 719 GIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755 Score = 82.0 bits (201), Expect = 9e-16 Identities = 47/99 (47%), Positives = 52/99 (52%), Gaps = 13/99 (13%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGP-----------PGQPGPRGSMGPMGPSPDL 294 PGP G+ G GP G PG GSPG PG G PG PGP+G G G P Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPG-YPGN 1093 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 IK G G G PG PG G+KG+ G PG G+PGPPG Sbjct: 1094 PGIK-GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131 Score = 81.6 bits (200), Expect = 1e-15 Identities = 42/85 (49%), Positives = 48/85 (56%), Gaps = 7/85 (8%) Query: 250 GLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPVGPP 308 G+ G +G G PG +G PG PG PGP G PGPRG G G P P G +G GPP Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGP------PGPKGIRGPP 95 Query: 309 GAPGRDGSKGERGAPGPRGSPGPPG 333 G PG G+ G G PG G+PGP G Sbjct: 96 GLPGFPGTPGLPGMPGHDGAPGPQG 120 Score = 81.3 bits (199), Expect = 1e-15 Identities = 50/121 (41%), Positives = 56/121 (46%), Gaps = 32/121 (26%) Query: 245 LPGPPGLPGGQGPPGSPG------PKGSPGFPG-----MPGPPGQPGPRGSMGPMGPSPD 293 LPGP G+PG GPPG PG P G PG G GP G+ G +G GP GP Sbjct: 184 LPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQ 243 Query: 294 LSHIKQ--------------GRRGPVGPPG-------APGRDGSKGERGAPGPRGSPGPP 332 +S K+ G RGP GPPG G G KGE+G PG RG PG Sbjct: 244 ISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303 Query: 333 G 333 G Sbjct: 304 G 304 Score = 80.5 bits (197), Expect = 3e-15 Identities = 39/88 (44%), Positives = 46/88 (52%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGP G+PG G PG G G G PG+PGP G+ G +G G GP + G +G Sbjct: 907 PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEK 966 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG PG G G +G G G PG PG Sbjct: 967 GEPGLPGIPGVSGPKGYQGLPGDPGQPG 994 Score = 80.1 bits (196), Expect = 3e-15 Identities = 50/133 (37%), Positives = 59/133 (44%), Gaps = 21/133 (15%) Query: 222 LPNNAADLGKYITGDKVLASNTYLPGPPGLPGG-------------QGPPGSPGPKGSPG 268 LP ++G G K L GPPG PG +G G PG +G PG Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPG 270 Query: 269 FPGMPGPPGQP-GPRGSMGPMG-------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGER 320 PG+ GPPG P G +G G G P D + + G G G PG PG G GE+ Sbjct: 271 PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEK 330 Query: 321 GAPGPRGSPGPPG 333 G G G PGPPG Sbjct: 331 GQKGDTGPPGPPG 343 Score = 80.1 bits (196), Expect = 3e-15 Identities = 47/112 (41%), Positives = 52/112 (46%), Gaps = 19/112 (16%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGP-----------KGSPGFPGMPGPPGQPGP 281 + GD L LPGP G G +G PG PGP KG G PG+PG PG GP Sbjct: 921 LKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP 980 Query: 282 RGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G G G G+ G G PG PG G KG G PG G GPPG Sbjct: 981 KGYQGLPG--------DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG 1024 Score = 79.7 bits (195), Expect = 4e-15 Identities = 48/125 (38%), Positives = 56/125 (44%), Gaps = 43/125 (34%) Query: 246 PGPPGLPGGQGP-----------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 PGPPG PG +G PG PG G PG PG+PGPPG GP + PS ++ Sbjct: 396 PGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPH-----IPPSDEI 450 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGA----------------------PGPRGSPGPP 332 GP GPPG+PG G +GE+G PG G PGPP Sbjct: 451 C-----EPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505 Query: 333 GSFDF 337 GS F Sbjct: 506 GSLGF 510 Score = 79.0 bits (193), Expect = 7e-15 Identities = 47/103 (45%), Positives = 54/103 (52%), Gaps = 3/103 (2%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SP 292 G+ L L GPPGL G G G PGP+G G PG G PGQPG G G G P Sbjct: 1009 GNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDP 1068 Query: 293 DLSHI-KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 +S I G GP G PG PG G+ G +G+ G G PG PG+ Sbjct: 1069 GISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGT 1111 Score = 78.6 bits (192), Expect = 1e-14 Identities = 49/105 (46%), Positives = 56/105 (53%), Gaps = 17/105 (16%) Query: 245 LPGPPGLP------GGQGPPGSPGP---KGSPGFPGMPGPPGQPGPR--GSMGPMGPSPD 293 +PG G+P G QG PG PGP KGS G PG+PGPPG P GS G G P Sbjct: 912 IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKG-EPG 970 Query: 294 LSHI-----KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 L I +G +G G PG PG G G G PGP+G+PG PG Sbjct: 971 LPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG 1015 Score = 76.6 bits (187), Expect = 4e-14 Identities = 47/112 (41%), Positives = 51/112 (45%), Gaps = 24/112 (21%) Query: 246 PGPPGLPGGQGP-----------PGSPGPKGSPGFPGMPGPPG------------QPGPR 282 PG PGLPG +G PG PGPKG PG PG PG PG PG Sbjct: 1053 PGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTP 1112 Query: 283 GSMGPMG-PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G+ G G P + G +G GPPG PG G G G G G PGPPG Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164 Score = 70.1 bits (170), Expect = 3e-12 Identities = 48/123 (39%), Positives = 51/123 (41%), Gaps = 43/123 (34%) Query: 246 PGPPGLPG----------------------GQGPPGSPGPKGSPGFPGMPGP---PGQPG 280 PGPPG PG G G G PG G PG PG PG PGQ G Sbjct: 456 PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKG 515 Query: 281 PRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGE----------RGAPGPRGSPG 330 +G G GP +G G G PGAPG GSKGE +G G GSPG Sbjct: 516 EKGQAGATGP--------KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPG 567 Query: 331 PPG 333 PG Sbjct: 568 APG 570 Score = 39.3 bits (90), Expect = 0.006 Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 2/57 (3%) Query: 277 GQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GQP + G SP G +G G G PG +G G G PGP G PGP G Sbjct: 21 GQPAEAAAC--YGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRG 75 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 101 bits (252), Expect = 1e-21 Identities = 55/101 (54%), Positives = 61/101 (60%), Gaps = 15/101 (14%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSM------GPMGPSP 292 LPGPPG PG G G+ GPKG GFPG PGPPG+ PGP+G + GPMGP P Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP-P 813 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 L I G +GP GPPG PG G G G PG +G PGPPG Sbjct: 814 GLPGI--GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG 852 Score = 101 bits (251), Expect = 1e-21 Identities = 52/102 (50%), Positives = 60/102 (58%), Gaps = 19/102 (18%) Query: 246 PGPPGLPGGQGPPGS------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299 PGPPG+PG +G PGS PGPKG+PG+PG PG G PGP G GP+GP Sbjct: 146 PGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG-----PP 200 Query: 300 GRRGPVGPPGAPGRDGS--------KGERGAPGPRGSPGPPG 333 G GP GPPG PG G+ KGE+G G +G PGPPG Sbjct: 201 GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG 242 Score = 98.6 bits (244), Expect = 9e-21 Identities = 56/111 (50%), Positives = 60/111 (54%), Gaps = 28/111 (25%) Query: 246 PGPPGLPG--GQ----------GPPGSPGPKGSPGFPGMPG------PPGQP-----GPR 282 PGPPGLPG GQ G PG PGPKG PGF G PG PPG P GP+ Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251 Query: 283 GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G+ GP GP + G GP GPPG PG G KGE+G PG G PG PG Sbjct: 1252 GNPGPQGPPG-----RPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1297 Score = 97.8 bits (242), Expect = 2e-20 Identities = 50/102 (49%), Positives = 59/102 (57%), Gaps = 10/102 (9%) Query: 242 NTYLPGPPGLPGGQGPPGSPGPKGSPGFPGM---PGPPGQPGPRGSMGPMGPSPDLSHIK 298 N PGPPG+ G GP G PGP G PG PG+ PGPPG PGP+G+MG P + Sbjct: 172 NPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGE 231 Query: 299 QGRRGPVGPPGAPGR-------DGSKGERGAPGPRGSPGPPG 333 QG +GP GPPG + KG++G PG RG PGPPG Sbjct: 232 QGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273 Score = 94.4 bits (233), Expect = 2e-19 Identities = 49/94 (52%), Positives = 55/94 (58%), Gaps = 11/94 (11%) Query: 246 PGPPGL------PGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299 PG PG+ PG G PG+PG KG PG PG PG PG PGP+G GP G +P L Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG-NPGL----P 1145 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GPVG G PG+ G GE+G PG G PGP G Sbjct: 1146 GEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179 Score = 93.6 bits (231), Expect = 3e-19 Identities = 58/117 (49%), Positives = 61/117 (52%), Gaps = 22/117 (18%) Query: 235 GDKVLASNTYLPGPPGLPG-----------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRG 283 GD L + LPG PGLPG G G PG PGPKG PG PG PG PG PG G Sbjct: 675 GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIG 734 Query: 284 SMGPMGPSPDLSHIKQ----GRRGPVGPPGAPGRDGS---KGERGAPGPRGSPGPPG 333 GP GP P K GP GPPG PG G+ KG+RG PGP PGPPG Sbjct: 735 LEGPPGP-PGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGP---PGPPG 787 Score = 93.6 bits (231), Expect = 3e-19 Identities = 48/100 (48%), Positives = 56/100 (56%), Gaps = 12/100 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGP 304 PG PGL G G PG PGPKG+PG PG PG G PG +G++G MG P P G G Sbjct: 990 PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049 Query: 305 VGPPGAPGRDGSKGER-----------GAPGPRGSPGPPG 333 G PG+PG G KG++ G PGP+G PG PG Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPG 1089 Score = 93.2 bits (230), Expect = 4e-19 Identities = 52/101 (51%), Positives = 56/101 (55%), Gaps = 14/101 (13%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGS-----MGPMGPSPDLSHIK-- 298 PGP G PG GPPG+PG G G G PGPPG PGP+G GP GP P L K Sbjct: 712 PGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGP-PGLPGFKGA 770 Query: 299 ---QGRRGPVGPPGAPGR---DGSKGERGAPGPRGSPGPPG 333 +G RG GPPG PGR DG G +G GP G PGP G Sbjct: 771 LGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMG 811 Score = 92.4 bits (228), Expect = 6e-19 Identities = 54/116 (46%), Positives = 57/116 (49%), Gaps = 7/116 (6%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPG-----GQGPPGSPGPKGSPGFPGMPGPPG 277 P D+G + GD L LPG PG G G G PG PGPKG PG PG PG PG Sbjct: 671 PGRDGDVG--LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPG 728 Query: 278 QPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 PG G GP GP + GPPG PG G KG G G RG PGPPG Sbjct: 729 TPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPG 784 Score = 91.7 bits (226), Expect = 1e-18 Identities = 48/96 (50%), Positives = 56/96 (58%), Gaps = 7/96 (7%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRG 303 +PGPPG G +GPPG PG G+PG PGMPG G PGP+G G G + G G Sbjct: 82 IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141 Query: 304 PVGPPGAPGRDGSKGERGA------PGPRGSPGPPG 333 GPPG PG G KGE G+ PGP+G+PG PG Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG 177 Score = 90.5 bits (223), Expect = 2e-18 Identities = 48/98 (48%), Positives = 52/98 (53%), Gaps = 11/98 (11%) Query: 247 GPPGLPG-----GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301 GPPGLPG GPPG PGP G PG G+PG G PGP G P P S G Sbjct: 811 GPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGA 870 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGS------PGPPG 333 GP+GPPG+PG G G G PG +G PGPPG Sbjct: 871 PGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908 Score = 90.5 bits (223), Expect = 2e-18 Identities = 45/91 (49%), Positives = 50/91 (54%), Gaps = 3/91 (3%) Query: 246 PGPPGL---PGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 PGP G+ PG G PG PGP G G PG PGPPG+ G G G GP+ Q Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GPPG PG G KG+ G PG G+PG PG Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPG 1220 Score = 89.0 bits (219), Expect = 7e-18 Identities = 52/109 (47%), Positives = 60/109 (55%), Gaps = 9/109 (8%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--P 290 I G+K L G PGLPG GP G PGP+G G G+PGPPG G RG G G Sbjct: 43 IKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPG 102 Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPG 333 +P L + G G GP G PG +G+KGERG PG +G PGPPG Sbjct: 103 TPGLPGM-PGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150 Score = 89.0 bits (219), Expect = 7e-18 Identities = 54/116 (46%), Positives = 63/116 (54%), Gaps = 19/116 (16%) Query: 235 GDKVLASNTYLPGPPGL-------------PGGQGPPGSPGPKGSPGFPGMPGPPGQPGP 281 G+K +T PGPPGL G G PG PG KG GFPG+ GPPG PGP Sbjct: 328 GEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP 387 Query: 282 RGS--MGPMGPSPDLSHIKQGRRGPVGPPG--APGRDGSKGERGAPGPRGSPGPPG 333 G+ MGP GP P ++G++G GPPG PG G G+ GAPG G PGP G Sbjct: 388 PGAAVMGPPGP-PGFPG-ERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAG 441 Score = 88.6 bits (218), Expect = 9e-18 Identities = 50/107 (46%), Positives = 58/107 (54%), Gaps = 12/107 (11%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGPS--------PD 293 +PGPPG G G PG+PGP G PG PG+PG G PG +G MG MGP P Sbjct: 855 VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG 914 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLL 340 S + G +G G G PG G GE+G+ G G PGPPG D LL Sbjct: 915 RSGV-PGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960 Score = 88.2 bits (217), Expect = 1e-17 Identities = 57/135 (42%), Positives = 62/135 (45%), Gaps = 28/135 (20%) Query: 222 LPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPP---------------GSPGPKGS 266 LP N I G+K LPG PGL G QGPP G PG G Sbjct: 1274 LPGNGG-----IKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGV 1328 Query: 267 PGFPGMPGP---PGQPGPRGSMGPMGPS-----PDLSHIKQGRRGPVGPPGAPGRDGSKG 318 PGFPGM GP PG GP G G +GP P S +G GPPG PG+ G KG Sbjct: 1329 PGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKG 1388 Query: 319 ERGAPGPRGSPGPPG 333 G GP+G PGP G Sbjct: 1389 LPGPQGPQGLPGPTG 1403 Score = 87.4 bits (215), Expect = 2e-17 Identities = 49/107 (45%), Positives = 56/107 (52%), Gaps = 19/107 (17%) Query: 246 PGPPGLPGGQGPPGSPGP---KGSPGFPGMPGPPGQPGPRGSMGPMG-----PSPDLSHI 297 PG PGLPG +GPPG PG KG G PG PG PG PG +G GP G P L+ + Sbjct: 1260 PGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGM 1319 Query: 298 K-----------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 K G +GP G PG+ G +G G G PGP G PGP G Sbjct: 1320 KGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG 1366 Score = 87.0 bits (214), Expect = 3e-17 Identities = 44/94 (46%), Positives = 52/94 (55%), Gaps = 7/94 (7%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL------SHIKQG 300 G PG G G PG PG G PG+PG PG G+ G +G GP GP P L + I G Sbjct: 298 GKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGP-PGLVIPRPGTGITIG 356 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 +G +G PG PG G +G G GP G PGPPG+ Sbjct: 357 EKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGA 390 Score = 85.9 bits (211), Expect = 6e-17 Identities = 48/92 (52%), Positives = 53/92 (57%), Gaps = 12/92 (13%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQ---PGPRGSMGPMGPSPDLSHIK 298 LPG PG PG G PG PGPKG PG F G GPPG PG G++GPMGP P Sbjct: 571 LPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGP-PGF---- 625 Query: 299 QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPG 330 G GPVG G G G+ G+ G PGP+G PG Sbjct: 626 -GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656 Score = 85.5 bits (210), Expect = 8e-17 Identities = 49/117 (41%), Positives = 56/117 (47%), Gaps = 27/117 (23%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPG----------FPGMPGPPGQPGPRGSMGPMGPSPD- 293 +PGPPGL G G PG PGP G G PG PGPPG PG +G G G D Sbjct: 418 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDK 477 Query: 294 ----LSHIKQGRRGPVGPPGA------------PGRDGSKGERGAPGPRGSPGPPGS 334 + I G GP G PG PG+ G KG+ GA GP+G PG PG+ Sbjct: 478 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGA 534 Score = 85.5 bits (210), Expect = 8e-17 Identities = 48/102 (47%), Positives = 53/102 (51%), Gaps = 9/102 (8%) Query: 242 NTYLPGPPGLPGGQGPPGSPGP---KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIK 298 N LPG PG GG G PG PGP KG PG G+PGP GQ G G G P P Sbjct: 1141 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1200 Query: 299 QGRRGPVGPPGAPGRDGSKGERGA------PGPRGSPGPPGS 334 G++G G PG PG G G +G PG +G PGPPGS Sbjct: 1201 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS 1242 Score = 84.7 bits (208), Expect = 1e-16 Identities = 47/107 (43%), Positives = 52/107 (48%), Gaps = 16/107 (14%) Query: 246 PGPPGLPGGQGPPGS---------------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGP 290 PG PGLPG GPPGS GPKG PG PG PG PG PG +G G + Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552 Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 P + K G G G PG PG G+ G+ G PG G G PG F Sbjct: 553 FPGMKGDK-GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITF 598 Score = 84.7 bits (208), Expect = 1e-16 Identities = 50/96 (52%), Positives = 53/96 (55%), Gaps = 8/96 (8%) Query: 243 TYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 T L G PG G GP G PGP G PG PG+ G G PGP G GP+G P L H G + Sbjct: 789 TGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIPGPIG-QPGL-HGIPGEK 845 Query: 303 GPVGP-----PGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP PG PG GS G GAPGP G PG PG Sbjct: 846 GDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881 Score = 84.3 bits (207), Expect = 2e-16 Identities = 52/111 (46%), Positives = 57/111 (51%), Gaps = 12/111 (10%) Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGS----PGPK------GSPGFPGMPGPPGQPGPRG 283 TG K L PG PG PG +G PG PG K GSPG PG+PG PG PG G Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582 Query: 284 SMGPMGPSPDLSHIK-QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP + I +G RGP G PG PG G+ G G PG G PGP G Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVG 632 Score = 84.3 bits (207), Expect = 2e-16 Identities = 56/135 (41%), Positives = 65/135 (48%), Gaps = 22/135 (16%) Query: 222 LPNNAADLGKYIT--------GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMP 273 +P D G+ IT G+ + LPG PGLPG G PG PG KG PG PG+ Sbjct: 648 IPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI- 706 Query: 274 GPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERG-----------A 322 G PG PGP+G G P P + GR G GPPG PG G KGE G Sbjct: 707 GLPGPPGPKGFPGI--PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL 764 Query: 323 PGPRGSPGPPGSFDF 337 PG +G+ GP G F Sbjct: 765 PGFKGALGPKGDRGF 779 Score = 83.2 bits (204), Expect = 4e-16 Identities = 49/107 (45%), Positives = 58/107 (54%), Gaps = 18/107 (16%) Query: 246 PGPPGLPGG--QGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--------PDLS 295 PGPPG PG +GP G+PGP+G PG PG+PGP G PG G+ G G P L Sbjct: 1237 PGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLP 1296 Query: 296 HIK--QGRRGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPGS 334 +K QG G G PG PG +G KG+ G PG +G G PGS Sbjct: 1297 GLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS 1343 Score = 83.2 bits (204), Expect = 4e-16 Identities = 48/100 (48%), Positives = 52/100 (52%), Gaps = 16/100 (16%) Query: 246 PGPPGLPG--GQ--------GPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PD 293 PGPPGLPG GQ GPPG PG G G PG GP G PGP G G G + P Sbjct: 1356 PGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPG 1415 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G G PG PG+ G++G G PGP G GPPG Sbjct: 1416 F----DGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG 1451 Score = 82.8 bits (203), Expect = 5e-16 Identities = 42/88 (47%), Positives = 47/88 (53%), Gaps = 8/88 (9%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GPPG+PG G G PGP+G G PG GPPG PG G G G GR+G G Sbjct: 1376 GPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAG--------GRKGDPG 1427 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGS 334 PG PG G G G G +G PGPPG+ Sbjct: 1428 LPGQPGTRGLDGPPGPDGLQGPPGPPGT 1455 Score = 82.4 bits (202), Expect = 7e-16 Identities = 49/115 (42%), Positives = 53/115 (46%), Gaps = 14/115 (12%) Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGP------------KGSPGFPGMPGPPGQ 278 K I G L PG PG+PG G PG G GSPGFPG+ GPPG Sbjct: 89 KGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGP 148 Query: 279 PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 PG G G P + G +G G PG PG G G G PGP G PGPPG Sbjct: 149 PGIPGMKGE--PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201 Score = 82.0 bits (201), Expect = 9e-16 Identities = 47/97 (48%), Positives = 49/97 (50%), Gaps = 9/97 (9%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG---PMGPSPDLSHIKQGRR 302 PG PG PG G G PG G PG PG+PG PG G G G P P P +G Sbjct: 665 PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGP------KGFP 718 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLL 339 G GPPGAPG G G G PGP G PGP G F L Sbjct: 719 GIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755 Score = 82.0 bits (201), Expect = 9e-16 Identities = 47/99 (47%), Positives = 52/99 (52%), Gaps = 13/99 (13%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGP-----------PGQPGPRGSMGPMGPSPDL 294 PGP G+ G GP G PG GSPG PG G PG PGP+G G G P Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPG-YPGN 1093 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 IK G G G PG PG G+KG+ G PG G+PGPPG Sbjct: 1094 PGIK-GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131 Score = 81.6 bits (200), Expect = 1e-15 Identities = 42/85 (49%), Positives = 48/85 (56%), Gaps = 7/85 (8%) Query: 250 GLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPVGPP 308 G+ G +G G PG +G PG PG PGP G PGPRG G G P P G +G GPP Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGP------PGPKGIRGPP 95 Query: 309 GAPGRDGSKGERGAPGPRGSPGPPG 333 G PG G+ G G PG G+PGP G Sbjct: 96 GLPGFPGTPGLPGMPGHDGAPGPQG 120 Score = 81.3 bits (199), Expect = 1e-15 Identities = 50/121 (41%), Positives = 56/121 (46%), Gaps = 32/121 (26%) Query: 245 LPGPPGLPGGQGPPGSPG------PKGSPGFPG-----MPGPPGQPGPRGSMGPMGPSPD 293 LPGP G+PG GPPG PG P G PG G GP G+ G +G GP GP Sbjct: 184 LPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQ 243 Query: 294 LSHIKQ--------------GRRGPVGPPG-------APGRDGSKGERGAPGPRGSPGPP 332 +S K+ G RGP GPPG G G KGE+G PG RG PG Sbjct: 244 ISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303 Query: 333 G 333 G Sbjct: 304 G 304 Score = 80.5 bits (197), Expect = 3e-15 Identities = 43/92 (46%), Positives = 50/92 (54%), Gaps = 5/92 (5%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP----SPDLSHIKQGR 301 PGP G+PG G PG G G G PG+PGP G+ G +G G GP P+L K G Sbjct: 907 PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK-GE 965 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G G PG PG G KG +G PG G PG G Sbjct: 966 KGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSG 997 Score = 80.1 bits (196), Expect = 3e-15 Identities = 50/133 (37%), Positives = 59/133 (44%), Gaps = 21/133 (15%) Query: 222 LPNNAADLGKYITGDKVLASNTYLPGPPGLPGG-------------QGPPGSPGPKGSPG 268 LP ++G G K L GPPG PG +G G PG +G PG Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPG 270 Query: 269 FPGMPGPPGQP-GPRGSMGPMG-------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGER 320 PG+ GPPG P G +G G G P D + + G G G PG PG G GE+ Sbjct: 271 PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEK 330 Query: 321 GAPGPRGSPGPPG 333 G G G PGPPG Sbjct: 331 GQKGDTGPPGPPG 343 Score = 80.1 bits (196), Expect = 3e-15 Identities = 47/112 (41%), Positives = 52/112 (46%), Gaps = 19/112 (16%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGP-----------KGSPGFPGMPGPPGQPGP 281 + GD L LPGP G G +G PG PGP KG G PG+PG PG GP Sbjct: 921 LKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP 980 Query: 282 RGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G G G G+ G G PG PG G KG G PG G GPPG Sbjct: 981 KGYQGLPG--------DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG 1024 Score = 79.7 bits (195), Expect = 4e-15 Identities = 48/125 (38%), Positives = 56/125 (44%), Gaps = 43/125 (34%) Query: 246 PGPPGLPGGQGP-----------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 PGPPG PG +G PG PG G PG PG+PGPPG GP + PS ++ Sbjct: 396 PGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPH-----IPPSDEI 450 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGA----------------------PGPRGSPGPP 332 GP GPPG+PG G +GE+G PG G PGPP Sbjct: 451 C-----EPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505 Query: 333 GSFDF 337 GS F Sbjct: 506 GSLGF 510 Score = 79.0 bits (193), Expect = 7e-15 Identities = 47/103 (45%), Positives = 54/103 (52%), Gaps = 3/103 (2%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SP 292 G+ L L GPPGL G G G PGP+G G PG G PGQPG G G G P Sbjct: 1009 GNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDP 1068 Query: 293 DLSHI-KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 +S I G GP G PG PG G+ G +G+ G G PG PG+ Sbjct: 1069 GISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGT 1111 Score = 78.6 bits (192), Expect = 1e-14 Identities = 49/105 (46%), Positives = 56/105 (53%), Gaps = 17/105 (16%) Query: 245 LPGPPGLP------GGQGPPGSPGP---KGSPGFPGMPGPPGQPGPR--GSMGPMGPSPD 293 +PG G+P G QG PG PGP KGS G PG+PGPPG P GS G G P Sbjct: 912 IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKG-EPG 970 Query: 294 LSHI-----KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 L I +G +G G PG PG G G G PGP+G+PG PG Sbjct: 971 LPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG 1015 Score = 76.6 bits (187), Expect = 4e-14 Identities = 47/112 (41%), Positives = 51/112 (45%), Gaps = 24/112 (21%) Query: 246 PGPPGLPGGQGP-----------PGSPGPKGSPGFPGMPGPPG------------QPGPR 282 PG PGLPG +G PG PGPKG PG PG PG PG PG Sbjct: 1053 PGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTP 1112 Query: 283 GSMGPMG-PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G+ G G P + G +G GPPG PG G G G G G PGPPG Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164 Score = 70.1 bits (170), Expect = 3e-12 Identities = 48/123 (39%), Positives = 51/123 (41%), Gaps = 43/123 (34%) Query: 246 PGPPGLPG----------------------GQGPPGSPGPKGSPGFPGMPGP---PGQPG 280 PGPPG PG G G G PG G PG PG PG PGQ G Sbjct: 456 PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKG 515 Query: 281 PRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGE----------RGAPGPRGSPG 330 +G G GP +G G G PGAPG GSKGE +G G GSPG Sbjct: 516 EKGQAGATGP--------KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPG 567 Query: 331 PPG 333 PG Sbjct: 568 APG 570 Score = 39.3 bits (90), Expect = 0.006 Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 2/57 (3%) Query: 277 GQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GQP + G SP G +G G G PG +G G G PGP G PGP G Sbjct: 21 GQPAEAAAC--YGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRG 75 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 101 bits (252), Expect = 1e-21 Identities = 55/101 (54%), Positives = 61/101 (60%), Gaps = 15/101 (14%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSM------GPMGPSP 292 LPGPPG PG G G+ GPKG GFPG PGPPG+ PGP+G + GPMGP P Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP-P 813 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 L I G +GP GPPG PG G G G PG +G PGPPG Sbjct: 814 GLPGI--GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG 852 Score = 101 bits (251), Expect = 1e-21 Identities = 52/102 (50%), Positives = 60/102 (58%), Gaps = 19/102 (18%) Query: 246 PGPPGLPGGQGPPGS------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299 PGPPG+PG +G PGS PGPKG+PG+PG PG G PGP G GP+GP Sbjct: 146 PGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG-----PP 200 Query: 300 GRRGPVGPPGAPGRDGS--------KGERGAPGPRGSPGPPG 333 G GP GPPG PG G+ KGE+G G +G PGPPG Sbjct: 201 GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG 242 Score = 99.0 bits (245), Expect = 7e-21 Identities = 57/111 (51%), Positives = 60/111 (54%), Gaps = 25/111 (22%) Query: 246 PGPPGLPG--GQ----------GPPGSPGPKGSPGFPGMPG------PPGQP-----GPR 282 PGPPGLPG GQ G PG PGPKG PGF G PG PPG P GP+ Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251 Query: 283 GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G+ GP GP QG GP GPPG PG G KGE+G PG G PG PG Sbjct: 1252 GNPGPQGPPGRPGF--QGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1300 Score = 97.8 bits (242), Expect = 2e-20 Identities = 50/102 (49%), Positives = 59/102 (57%), Gaps = 10/102 (9%) Query: 242 NTYLPGPPGLPGGQGPPGSPGPKGSPGFPGM---PGPPGQPGPRGSMGPMGPSPDLSHIK 298 N PGPPG+ G GP G PGP G PG PG+ PGPPG PGP+G+MG P + Sbjct: 172 NPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGE 231 Query: 299 QGRRGPVGPPGAPGR-------DGSKGERGAPGPRGSPGPPG 333 QG +GP GPPG + KG++G PG RG PGPPG Sbjct: 232 QGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273 Score = 94.4 bits (233), Expect = 2e-19 Identities = 49/94 (52%), Positives = 55/94 (58%), Gaps = 11/94 (11%) Query: 246 PGPPGL------PGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299 PG PG+ PG G PG+PG KG PG PG PG PG PGP+G GP G +P L Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG-NPGL----P 1145 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GPVG G PG+ G GE+G PG G PGP G Sbjct: 1146 GEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179 Score = 93.6 bits (231), Expect = 3e-19 Identities = 58/117 (49%), Positives = 61/117 (52%), Gaps = 22/117 (18%) Query: 235 GDKVLASNTYLPGPPGLPG-----------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRG 283 GD L + LPG PGLPG G G PG PGPKG PG PG PG PG PG G Sbjct: 675 GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIG 734 Query: 284 SMGPMGPSPDLSHIKQ----GRRGPVGPPGAPGRDGS---KGERGAPGPRGSPGPPG 333 GP GP P K GP GPPG PG G+ KG+RG PGP PGPPG Sbjct: 735 LEGPPGP-PGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGP---PGPPG 787 Score = 93.6 bits (231), Expect = 3e-19 Identities = 48/100 (48%), Positives = 56/100 (56%), Gaps = 12/100 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGP 304 PG PGL G G PG PGPKG+PG PG PG G PG +G++G MG P P G G Sbjct: 990 PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049 Query: 305 VGPPGAPGRDGSKGER-----------GAPGPRGSPGPPG 333 G PG+PG G KG++ G PGP+G PG PG Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPG 1089 Score = 93.2 bits (230), Expect = 4e-19 Identities = 52/101 (51%), Positives = 56/101 (55%), Gaps = 14/101 (13%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGS-----MGPMGPSPDLSHIK-- 298 PGP G PG GPPG+PG G G G PGPPG PGP+G GP GP P L K Sbjct: 712 PGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGP-PGLPGFKGA 770 Query: 299 ---QGRRGPVGPPGAPGR---DGSKGERGAPGPRGSPGPPG 333 +G RG GPPG PGR DG G +G GP G PGP G Sbjct: 771 LGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMG 811 Score = 92.4 bits (228), Expect = 6e-19 Identities = 54/116 (46%), Positives = 57/116 (49%), Gaps = 7/116 (6%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPG-----GQGPPGSPGPKGSPGFPGMPGPPG 277 P D+G + GD L LPG PG G G G PG PGPKG PG PG PG PG Sbjct: 671 PGRDGDVG--LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPG 728 Query: 278 QPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 PG G GP GP + GPPG PG G KG G G RG PGPPG Sbjct: 729 TPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPG 784 Score = 91.7 bits (226), Expect = 1e-18 Identities = 48/96 (50%), Positives = 56/96 (58%), Gaps = 7/96 (7%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRG 303 +PGPPG G +GPPG PG G+PG PGMPG G PGP+G G G + G G Sbjct: 82 IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141 Query: 304 PVGPPGAPGRDGSKGERGA------PGPRGSPGPPG 333 GPPG PG G KGE G+ PGP+G+PG PG Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG 177 Score = 90.5 bits (223), Expect = 2e-18 Identities = 48/98 (48%), Positives = 52/98 (53%), Gaps = 11/98 (11%) Query: 247 GPPGLPG-----GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301 GPPGLPG GPPG PGP G PG G+PG G PGP G P P S G Sbjct: 811 GPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGA 870 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGS------PGPPG 333 GP+GPPG+PG G G G PG +G PGPPG Sbjct: 871 PGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908 Score = 90.5 bits (223), Expect = 2e-18 Identities = 45/91 (49%), Positives = 50/91 (54%), Gaps = 3/91 (3%) Query: 246 PGPPGL---PGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 PGP G+ PG G PG PGP G G PG PGPPG+ G G G GP+ Q Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GPPG PG G KG+ G PG G+PG PG Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPG 1220 Score = 89.0 bits (219), Expect = 7e-18 Identities = 52/109 (47%), Positives = 60/109 (55%), Gaps = 9/109 (8%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--P 290 I G+K L G PGLPG GP G PGP+G G G+PGPPG G RG G G Sbjct: 43 IKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPG 102 Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPG 333 +P L + G G GP G PG +G+KGERG PG +G PGPPG Sbjct: 103 TPGLPGM-PGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150 Score = 89.0 bits (219), Expect = 7e-18 Identities = 54/116 (46%), Positives = 63/116 (54%), Gaps = 19/116 (16%) Query: 235 GDKVLASNTYLPGPPGL-------------PGGQGPPGSPGPKGSPGFPGMPGPPGQPGP 281 G+K +T PGPPGL G G PG PG KG GFPG+ GPPG PGP Sbjct: 328 GEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP 387 Query: 282 RGS--MGPMGPSPDLSHIKQGRRGPVGPPG--APGRDGSKGERGAPGPRGSPGPPG 333 G+ MGP GP P ++G++G GPPG PG G G+ GAPG G PGP G Sbjct: 388 PGAAVMGPPGP-PGFPG-ERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAG 441 Score = 88.6 bits (218), Expect = 9e-18 Identities = 50/107 (46%), Positives = 58/107 (54%), Gaps = 12/107 (11%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGPS--------PD 293 +PGPPG G G PG+PGP G PG PG+PG G PG +G MG MGP P Sbjct: 855 VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG 914 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLL 340 S + G +G G G PG G GE+G+ G G PGPPG D LL Sbjct: 915 RSGV-PGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960 Score = 88.2 bits (217), Expect = 1e-17 Identities = 57/135 (42%), Positives = 62/135 (45%), Gaps = 28/135 (20%) Query: 222 LPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPP---------------GSPGPKGS 266 LP N I G+K LPG PGL G QGPP G PG G Sbjct: 1277 LPGNGG-----IKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGV 1331 Query: 267 PGFPGMPGP---PGQPGPRGSMGPMGPS-----PDLSHIKQGRRGPVGPPGAPGRDGSKG 318 PGFPGM GP PG GP G G +GP P S +G GPPG PG+ G KG Sbjct: 1332 PGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKG 1391 Query: 319 ERGAPGPRGSPGPPG 333 G GP+G PGP G Sbjct: 1392 LPGPQGPQGLPGPTG 1406 Score = 87.0 bits (214), Expect = 3e-17 Identities = 44/94 (46%), Positives = 52/94 (55%), Gaps = 7/94 (7%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL------SHIKQG 300 G PG G G PG PG G PG+PG PG G+ G +G GP GP P L + I G Sbjct: 298 GKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGP-PGLVIPRPGTGITIG 356 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 +G +G PG PG G +G G GP G PGPPG+ Sbjct: 357 EKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGA 390 Score = 85.9 bits (211), Expect = 6e-17 Identities = 48/92 (52%), Positives = 53/92 (57%), Gaps = 12/92 (13%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQ---PGPRGSMGPMGPSPDLSHIK 298 LPG PG PG G PG PGPKG PG F G GPPG PG G++GPMGP P Sbjct: 571 LPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGP-PGF---- 625 Query: 299 QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPG 330 G GPVG G G G+ G+ G PGP+G PG Sbjct: 626 -GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656 Score = 85.5 bits (210), Expect = 8e-17 Identities = 49/117 (41%), Positives = 56/117 (47%), Gaps = 27/117 (23%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPG----------FPGMPGPPGQPGPRGSMGPMGPSPD- 293 +PGPPGL G G PG PGP G G PG PGPPG PG +G G G D Sbjct: 418 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDK 477 Query: 294 ----LSHIKQGRRGPVGPPGA------------PGRDGSKGERGAPGPRGSPGPPGS 334 + I G GP G PG PG+ G KG+ GA GP+G PG PG+ Sbjct: 478 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGA 534 Score = 85.5 bits (210), Expect = 8e-17 Identities = 48/102 (47%), Positives = 53/102 (51%), Gaps = 9/102 (8%) Query: 242 NTYLPGPPGLPGGQGPPGSPGP---KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIK 298 N LPG PG GG G PG PGP KG PG G+PGP GQ G G G P P Sbjct: 1141 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1200 Query: 299 QGRRGPVGPPGAPGRDGSKGERGA------PGPRGSPGPPGS 334 G++G G PG PG G G +G PG +G PGPPGS Sbjct: 1201 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS 1242 Score = 84.7 bits (208), Expect = 1e-16 Identities = 47/107 (43%), Positives = 52/107 (48%), Gaps = 16/107 (14%) Query: 246 PGPPGLPGGQGPPGS---------------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGP 290 PG PGLPG GPPGS GPKG PG PG PG PG PG +G G + Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552 Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 P + K G G G PG PG G+ G+ G PG G G PG F Sbjct: 553 FPGMKGDK-GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITF 598 Score = 84.7 bits (208), Expect = 1e-16 Identities = 50/96 (52%), Positives = 53/96 (55%), Gaps = 8/96 (8%) Query: 243 TYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 T L G PG G GP G PGP G PG PG+ G G PGP G GP+G P L H G + Sbjct: 789 TGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIPGPIG-QPGL-HGIPGEK 845 Query: 303 GPVGP-----PGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP PG PG GS G GAPGP G PG PG Sbjct: 846 GDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881 Score = 84.3 bits (207), Expect = 2e-16 Identities = 52/111 (46%), Positives = 57/111 (51%), Gaps = 12/111 (10%) Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGS----PGPK------GSPGFPGMPGPPGQPGPRG 283 TG K L PG PG PG +G PG PG K GSPG PG+PG PG PG G Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582 Query: 284 SMGPMGPSPDLSHIK-QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP + I +G RGP G PG PG G+ G G PG G PGP G Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVG 632 Score = 84.3 bits (207), Expect = 2e-16 Identities = 56/135 (41%), Positives = 65/135 (48%), Gaps = 22/135 (16%) Query: 222 LPNNAADLGKYIT--------GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMP 273 +P D G+ IT G+ + LPG PGLPG G PG PG KG PG PG+ Sbjct: 648 IPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI- 706 Query: 274 GPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERG-----------A 322 G PG PGP+G G P P + GR G GPPG PG G KGE G Sbjct: 707 GLPGPPGPKGFPGI--PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL 764 Query: 323 PGPRGSPGPPGSFDF 337 PG +G+ GP G F Sbjct: 765 PGFKGALGPKGDRGF 779 Score = 83.6 bits (205), Expect = 3e-16 Identities = 48/107 (44%), Positives = 55/107 (51%), Gaps = 19/107 (17%) Query: 246 PGPPGLPGGQGPPGSPGP---KGSPGFPGMPGPPGQPGPRGSMGPMG-----PSPDLSHI 297 PG GLPG +GPPG PG KG G PG PG PG PG +G GP G P L+ + Sbjct: 1263 PGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGM 1322 Query: 298 K-----------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 K G +GP G PG+ G +G G G PGP G PGP G Sbjct: 1323 KGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG 1369 Score = 83.2 bits (204), Expect = 4e-16 Identities = 48/100 (48%), Positives = 52/100 (52%), Gaps = 16/100 (16%) Query: 246 PGPPGLPG--GQ--------GPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PD 293 PGPPGLPG GQ GPPG PG G G PG GP G PGP G G G + P Sbjct: 1359 PGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPG 1418 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G G PG PG+ G++G G PGP G GPPG Sbjct: 1419 F----DGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG 1454 Score = 82.8 bits (203), Expect = 5e-16 Identities = 42/88 (47%), Positives = 47/88 (53%), Gaps = 8/88 (9%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GPPG+PG G G PGP+G G PG GPPG PG G G G GR+G G Sbjct: 1379 GPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAG--------GRKGDPG 1430 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGS 334 PG PG G G G G +G PGPPG+ Sbjct: 1431 LPGQPGTRGLDGPPGPDGLQGPPGPPGT 1458 Score = 82.4 bits (202), Expect = 7e-16 Identities = 49/115 (42%), Positives = 53/115 (46%), Gaps = 14/115 (12%) Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGP------------KGSPGFPGMPGPPGQ 278 K I G L PG PG+PG G PG G GSPGFPG+ GPPG Sbjct: 89 KGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGP 148 Query: 279 PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 PG G G P + G +G G PG PG G G G PGP G PGPPG Sbjct: 149 PGIPGMKGE--PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201 Score = 82.0 bits (201), Expect = 9e-16 Identities = 47/97 (48%), Positives = 49/97 (50%), Gaps = 9/97 (9%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG---PMGPSPDLSHIKQGRR 302 PG PG PG G G PG G PG PG+PG PG G G G P P P +G Sbjct: 665 PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGP------KGFP 718 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLL 339 G GPPGAPG G G G PGP G PGP G F L Sbjct: 719 GIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755 Score = 82.0 bits (201), Expect = 9e-16 Identities = 47/99 (47%), Positives = 52/99 (52%), Gaps = 13/99 (13%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGP-----------PGQPGPRGSMGPMGPSPDL 294 PGP G+ G GP G PG GSPG PG G PG PGP+G G G P Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPG-YPGN 1093 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 IK G G G PG PG G+KG+ G PG G+PGPPG Sbjct: 1094 PGIK-GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131 Score = 81.6 bits (200), Expect = 1e-15 Identities = 42/85 (49%), Positives = 48/85 (56%), Gaps = 7/85 (8%) Query: 250 GLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPVGPP 308 G+ G +G G PG +G PG PG PGP G PGPRG G G P P G +G GPP Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGP------PGPKGIRGPP 95 Query: 309 GAPGRDGSKGERGAPGPRGSPGPPG 333 G PG G+ G G PG G+PGP G Sbjct: 96 GLPGFPGTPGLPGMPGHDGAPGPQG 120 Score = 81.3 bits (199), Expect = 1e-15 Identities = 50/121 (41%), Positives = 56/121 (46%), Gaps = 32/121 (26%) Query: 245 LPGPPGLPGGQGPPGSPG------PKGSPGFPG-----MPGPPGQPGPRGSMGPMGPSPD 293 LPGP G+PG GPPG PG P G PG G GP G+ G +G GP GP Sbjct: 184 LPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQ 243 Query: 294 LSHIKQ--------------GRRGPVGPPG-------APGRDGSKGERGAPGPRGSPGPP 332 +S K+ G RGP GPPG G G KGE+G PG RG PG Sbjct: 244 ISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303 Query: 333 G 333 G Sbjct: 304 G 304 Score = 80.9 bits (198), Expect = 2e-15 Identities = 46/91 (50%), Positives = 51/91 (56%), Gaps = 3/91 (3%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PDLSHIKQGRR 302 L GP G PG QGPPG PG +G PG G PG PG G +G G G P L +K G + Sbjct: 1247 LEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK-GDQ 1305 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G G PGR G G +G PG G PG PG Sbjct: 1306 GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG 1336 Score = 80.5 bits (197), Expect = 3e-15 Identities = 39/88 (44%), Positives = 46/88 (52%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGP G+PG G PG G G G PG+PGP G+ G +G G GP + G +G Sbjct: 907 PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEK 966 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG PG G G +G G G PG PG Sbjct: 967 GEPGLPGIPGVSGPKGYQGLPGDPGQPG 994 Score = 80.1 bits (196), Expect = 3e-15 Identities = 50/133 (37%), Positives = 59/133 (44%), Gaps = 21/133 (15%) Query: 222 LPNNAADLGKYITGDKVLASNTYLPGPPGLPGG-------------QGPPGSPGPKGSPG 268 LP ++G G K L GPPG PG +G G PG +G PG Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPG 270 Query: 269 FPGMPGPPGQP-GPRGSMGPMG-------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGER 320 PG+ GPPG P G +G G G P D + + G G G PG PG G GE+ Sbjct: 271 PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEK 330 Query: 321 GAPGPRGSPGPPG 333 G G G PGPPG Sbjct: 331 GQKGDTGPPGPPG 343 Score = 80.1 bits (196), Expect = 3e-15 Identities = 47/112 (41%), Positives = 52/112 (46%), Gaps = 19/112 (16%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGP-----------KGSPGFPGMPGPPGQPGP 281 + GD L LPGP G G +G PG PGP KG G PG+PG PG GP Sbjct: 921 LKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP 980 Query: 282 RGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G G G G+ G G PG PG G KG G PG G GPPG Sbjct: 981 KGYQGLPG--------DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG 1024 Score = 79.7 bits (195), Expect = 4e-15 Identities = 48/125 (38%), Positives = 56/125 (44%), Gaps = 43/125 (34%) Query: 246 PGPPGLPGGQGP-----------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 PGPPG PG +G PG PG G PG PG+PGPPG GP + PS ++ Sbjct: 396 PGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPH-----IPPSDEI 450 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGA----------------------PGPRGSPGPP 332 GP GPPG+PG G +GE+G PG G PGPP Sbjct: 451 C-----EPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505 Query: 333 GSFDF 337 GS F Sbjct: 506 GSLGF 510 Score = 79.0 bits (193), Expect = 7e-15 Identities = 47/103 (45%), Positives = 54/103 (52%), Gaps = 3/103 (2%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SP 292 G+ L L GPPGL G G G PGP+G G PG G PGQPG G G G P Sbjct: 1009 GNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDP 1068 Query: 293 DLSHI-KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 +S I G GP G PG PG G+ G +G+ G G PG PG+ Sbjct: 1069 GISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGT 1111 Score = 78.6 bits (192), Expect = 1e-14 Identities = 49/105 (46%), Positives = 56/105 (53%), Gaps = 17/105 (16%) Query: 245 LPGPPGLP------GGQGPPGSPGP---KGSPGFPGMPGPPGQPGPR--GSMGPMGPSPD 293 +PG G+P G QG PG PGP KGS G PG+PGPPG P GS G G P Sbjct: 912 IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKG-EPG 970 Query: 294 LSHI-----KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 L I +G +G G PG PG G G G PGP+G+PG PG Sbjct: 971 LPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG 1015 Score = 76.6 bits (187), Expect = 4e-14 Identities = 47/112 (41%), Positives = 51/112 (45%), Gaps = 24/112 (21%) Query: 246 PGPPGLPGGQGP-----------PGSPGPKGSPGFPGMPGPPG------------QPGPR 282 PG PGLPG +G PG PGPKG PG PG PG PG PG Sbjct: 1053 PGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTP 1112 Query: 283 GSMGPMG-PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G+ G G P + G +G GPPG PG G G G G G PGPPG Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164 Score = 70.1 bits (170), Expect = 3e-12 Identities = 48/123 (39%), Positives = 51/123 (41%), Gaps = 43/123 (34%) Query: 246 PGPPGLPG----------------------GQGPPGSPGPKGSPGFPGMPGP---PGQPG 280 PGPPG PG G G G PG G PG PG PG PGQ G Sbjct: 456 PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKG 515 Query: 281 PRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGE----------RGAPGPRGSPG 330 +G G GP +G G G PGAPG GSKGE +G G GSPG Sbjct: 516 EKGQAGATGP--------KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPG 567 Query: 331 PPG 333 PG Sbjct: 568 APG 570 Score = 39.3 bits (90), Expect = 0.006 Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 2/57 (3%) Query: 277 GQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GQP + G SP G +G G G PG +G G G PGP G PGP G Sbjct: 21 GQPAEAAAC--YGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRG 75 >gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] Length = 1860 Score = 101 bits (251), Expect = 1e-21 Identities = 60/134 (44%), Positives = 70/134 (52%), Gaps = 30/134 (22%) Query: 245 LPGPPGLPGGQG------PPGSPGPKGSPGFPGMP---GPPGQPGPRGSMGPMGPSPDLS 295 L G PG+ G +G PPG PGPKGS G PGMP G PG+PGP+G G GP P + Sbjct: 1001 LVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGP-PGMR 1059 Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQEK 355 K GRRGP GP G G GS+G +G PGP+G PG PG Q+ Sbjct: 1060 GAK-GRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPG-------------------QQG 1099 Query: 356 VFGHRTHSSAEEFP 369 V G R H + FP Sbjct: 1100 VAGERGHLGSRGFP 1113 Score = 95.5 bits (236), Expect = 8e-20 Identities = 51/106 (48%), Positives = 60/106 (56%), Gaps = 7/106 (6%) Query: 235 GDKVLASNTYLPGP------PGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPM 288 GD+ + +PGP PG+PGG G PG PGP+G PG G PG G G RG GP Sbjct: 1012 GDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPD 1071 Query: 289 GPSPDL-SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP+ + S +G GP G PG PG+ G GERG G RG PG PG Sbjct: 1072 GPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPG 1117 Score = 95.1 bits (235), Expect = 1e-19 Identities = 58/118 (49%), Positives = 64/118 (54%), Gaps = 11/118 (9%) Query: 229 LGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGP---KGSPGFPGMPGPPGQPGPRGSM 285 LGK GDK PGP G PG GPPG GP KG PG G+PGP GQ GP G Sbjct: 891 LGK--VGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDE 948 Query: 286 GPMGP--SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLM 341 GPMGP +P L +G+ G G PG PG DG KGE G PG G G G F+ L+ Sbjct: 949 GPMGPPGAPGL----EGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLV 1002 Score = 94.0 bits (232), Expect = 2e-19 Identities = 48/92 (52%), Positives = 55/92 (59%), Gaps = 5/92 (5%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 LPGPPGLPG G PG+ GP+G PG G PG PG PG +G G G SP +H G +G Sbjct: 635 LPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAH--DGAKGD 692 Query: 305 VGPPGA---PGRDGSKGERGAPGPRGSPGPPG 333 +G PG PG G KG +G PGP G PG G Sbjct: 693 MGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQG 724 Score = 89.4 bits (220), Expect = 5e-18 Identities = 51/131 (38%), Positives = 59/131 (45%), Gaps = 29/131 (22%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---------------- 278 GD L LPG PG+PG +GP G PGP G+PG PG PG GQ Sbjct: 631 GDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAK 690 Query: 279 -----------PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRG 327 PGP G G G H G +G GP G+PG G G +G PGP G Sbjct: 691 GDMGLPGLSGNPGPPGRKGHKGYPGPAGH--PGEQGQPGPEGSPGAKGYPGRQGLPGPVG 748 Query: 328 SPGPPGSFDFL 338 PGP GS ++ Sbjct: 749 DPGPKGSRGYI 759 Score = 87.4 bits (215), Expect = 2e-17 Identities = 56/131 (42%), Positives = 64/131 (48%), Gaps = 24/131 (18%) Query: 222 LPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP---PGQ 278 +P + D G GDK + LPG PG G GP G G KGS GFPG PGP PG Sbjct: 860 VPGVSGDPG--FQGDK---GSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGD 914 Query: 279 PGPRGSMGPMG----------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAP----- 323 GP G GP G P P +G GP+GPPGAPG +G G +G P Sbjct: 915 IGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGL 974 Query: 324 -GPRGSPGPPG 333 G +G PG PG Sbjct: 975 DGVKGEPGDPG 985 Score = 86.7 bits (213), Expect = 4e-17 Identities = 48/91 (52%), Positives = 53/91 (58%), Gaps = 5/91 (5%) Query: 246 PGPPGLPGGQGPPG---SPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 PGP G PG QG PG SPG KG PG G+PGP G PGP+GS G +G P L + G Sbjct: 714 PGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIG-LPGLFGL-PGSD 771 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G PG PG+ G G G PG G GPPG Sbjct: 772 GERGLPGVPGKRGKMGMPGFPGVFGERGPPG 802 Score = 86.7 bits (213), Expect = 4e-17 Identities = 48/100 (48%), Positives = 52/100 (52%), Gaps = 20/100 (20%) Query: 246 PGP---PGLPGGQGPPGSPGPKGSPGFPGMPGP---------PGQPGPRGSMGPMGPSPD 293 PGP PG PG QG G G GS GFPG+PGP PG+PGP+G GP+GP Sbjct: 1086 PGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGP--- 1142 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP GPPGA G G GE G G G G PG Sbjct: 1143 -----PGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPG 1177 Score = 86.3 bits (212), Expect = 5e-17 Identities = 44/97 (45%), Positives = 52/97 (53%), Gaps = 10/97 (10%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI--------- 297 GP G PG G G PG KG PG PG+ G G+PG G GP+G + I Sbjct: 949 GPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIV 1008 Query: 298 -KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 ++G RG +GPPG PG GS G G PG G+PG PG Sbjct: 1009 GEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPG 1045 Score = 86.3 bits (212), Expect = 5e-17 Identities = 46/101 (45%), Positives = 53/101 (52%), Gaps = 13/101 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ------ 299 PGP G G GPPG GPKG PG G PG PG+ G +G +GP+G + I Q Sbjct: 1131 PGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGL 1190 Query: 300 -GRRGPVGPPGA------PGRDGSKGERGAPGPRGSPGPPG 333 G GP+GP G PG DG GE+G G G GPPG Sbjct: 1191 EGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPG 1231 Score = 85.5 bits (210), Expect = 8e-17 Identities = 49/101 (48%), Positives = 57/101 (56%), Gaps = 14/101 (13%) Query: 239 LASNTYLP---GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLS 295 LA +T P GPPG G G PG PG G PG PG GP G PGP G+ G GP Sbjct: 614 LAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGP----- 668 Query: 296 HIKQGRRGPVGPPG-APGR--DGSKGERGAPGPRGSPGPPG 333 G +G G PG +PG+ DG+KG+ G PG G+PGPPG Sbjct: 669 ---PGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPG 706 Score = 85.1 bits (209), Expect = 1e-16 Identities = 52/114 (45%), Positives = 58/114 (50%), Gaps = 17/114 (14%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGP---RGSMGPMGPS 291 G + T LPG G PG +G PG G G PG G+ GP G PG +G GP GP Sbjct: 1505 GKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGP- 1563 Query: 292 PDLSHIKQGRRGP---VGPPGAPGRDGSKGE---------RGAPGPRGSPGPPG 333 P L K+G GP +GP G PG G KG RG PGPRG PGPPG Sbjct: 1564 PGLMG-KEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPG 1616 Score = 84.7 bits (208), Expect = 1e-16 Identities = 45/92 (48%), Positives = 49/92 (53%), Gaps = 6/92 (6%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP-----SPDLSHIKQGR 301 G G PG GP G PG KG PG PG GP G GP G MGP GP P L + G Sbjct: 1108 GSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPG-EAGM 1166 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G +GP G PG G G+RG PG G GP G Sbjct: 1167 KGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMG 1198 Score = 84.3 bits (207), Expect = 2e-16 Identities = 49/118 (41%), Positives = 58/118 (49%), Gaps = 31/118 (26%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPG------------------FPGMPGPPGQPGPRGSMGP 287 PGPPG+ G +GP G G +G G PG PGPPG PGP+GS G Sbjct: 1230 PGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGS 1289 Query: 288 MGPS-----------PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPG-PRGSPGPPG 333 +GP+ P L+ G +G VGP G PG G KGE+G G G PGPPG Sbjct: 1290 LGPTGAPGRMGAQGEPGLAGY-DGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPG 1346 Score = 83.6 bits (205), Expect = 3e-16 Identities = 46/97 (47%), Positives = 52/97 (53%), Gaps = 10/97 (10%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMP---------GPPGQPGPRGSMGPMG-PSPDLSH 296 GPPG PG +GP G G +G PG PG P G PGQ G G GP G P P S Sbjct: 1340 GPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSK 1399 Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G +G G GAPGR G +G +G PGPRG G G Sbjct: 1400 GAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQG 1436 Score = 82.8 bits (203), Expect = 5e-16 Identities = 45/94 (47%), Positives = 52/94 (55%), Gaps = 10/94 (10%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----PSPDLSHIKQGRR 302 G G+PG G PG G KGS G PG PG G+PGP G +G G P P +G Sbjct: 856 GEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPP---GPEGFP 912 Query: 303 GPVGPPGAPGRDGSKGE---RGAPGPRGSPGPPG 333 G +GPPG G +G KG+ RG PGPRG GP G Sbjct: 913 GDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEG 946 Score = 82.0 bits (201), Expect = 9e-16 Identities = 53/120 (44%), Positives = 61/120 (50%), Gaps = 16/120 (13%) Query: 221 LLPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQG---PPGSPGPKGSPGFPGMPGPPG 277 L P A D K GD L + PGPPG G +G P G PG +G PG G PG G Sbjct: 680 LSPGKAHDGAK---GDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKG 736 Query: 278 QPGPRGSMGPMG-PSPDLSHIKQGRRGPVGPP---GAPGRDGSKGERGAPGPRGSPGPPG 333 PG +G GP+G P P +G RG +G P G PG DG +G G PG RG G PG Sbjct: 737 YPGRQGLPGPVGDPGP------KGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPG 790 Score = 82.0 bits (201), Expect = 9e-16 Identities = 45/110 (40%), Positives = 52/110 (47%), Gaps = 22/110 (20%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--------SPDLSHI 297 PG PG PG +G G G G G PG PGP G PGP+GS G GP +P + Sbjct: 1360 PGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGV 1419 Query: 298 --------------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +QG G GP G PGRDG G++G G G PGP G Sbjct: 1420 QGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMG 1469 Score = 80.5 bits (197), Expect = 3e-15 Identities = 50/124 (40%), Positives = 59/124 (47%), Gaps = 35/124 (28%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPG---------------FPGMPGPPGQPGPRGSMG---- 286 PGPPG PG +G GS GP G+PG G+ GP G PGP+G G Sbjct: 1275 PGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGE 1334 Query: 287 ------PMGPSPDLSHI-KQGRRGPVGPPGAPGRDGSKGERGAPG---------PRGSPG 330 P GP D + +G RG G PG PG++G +G RG PG PRG PG Sbjct: 1335 DGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPG 1394 Query: 331 PPGS 334 P GS Sbjct: 1395 PKGS 1398 Score = 80.1 bits (196), Expect = 3e-15 Identities = 45/99 (45%), Positives = 51/99 (51%), Gaps = 14/99 (14%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFP---GMPGPPGQPGPRGSM---------GPMGPSPDL 294 G GLPG GPPG G +G G P G PG GQPG G M GP GP D+ Sbjct: 1493 GESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDI 1552 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G +GP GPPG G++G G G GP G PGP G Sbjct: 1553 GF--KGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKG 1589 Score = 80.1 bits (196), Expect = 3e-15 Identities = 54/111 (48%), Positives = 57/111 (51%), Gaps = 26/111 (23%) Query: 247 GPPGLPGGQGPPGS---PGPKGSPGFPGMPG------PPGQPGPRGSMGPMGPSPDLSHI 297 G GLPG QG PGS PG G GFPGM G PPG G +G GP GP P L Sbjct: 1511 GRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGP-PGLMG- 1568 Query: 298 KQGRRGPVG---PPGAPGRDGSKGERG---------APGPRGS---PGPPG 333 K+G GP+G P G PG G KG RG PGPRG PGPPG Sbjct: 1569 KEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPG 1619 Score = 79.7 bits (195), Expect = 4e-15 Identities = 43/90 (47%), Positives = 48/90 (53%), Gaps = 5/90 (5%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 LPGP G+ G QG G GP G PG G G G+ G G GPMGP+ K+G G Sbjct: 1425 LPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAG-----KRGNPGV 1479 Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G PGA G G KGE G PG G PG G+ Sbjct: 1480 AGLPGAQGPPGFKGESGLPGQLGPPGKRGT 1509 Score = 79.3 bits (194), Expect = 6e-15 Identities = 42/90 (46%), Positives = 51/90 (56%), Gaps = 7/90 (7%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRG 303 +PG PG+ G +GPPG G G G PG PG PG G G +GP+G P P +G +G Sbjct: 788 MPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGP------KGMKG 841 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G G PG G KGE+G PG G PG G Sbjct: 842 LMGSVGEPGLKGDKGEQGVPGVSGDPGFQG 871 Score = 77.8 bits (190), Expect = 2e-14 Identities = 47/102 (46%), Positives = 51/102 (50%), Gaps = 11/102 (10%) Query: 245 LPGPPGLPG------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIK 298 LPGPPG+PG GP G PGPKG G G G PG G +G G G S D Sbjct: 812 LPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGF-- 869 Query: 299 QGRRGPVGPPGAPGRDGSKGERGAPGPRGS---PGPPGSFDF 337 QG +G G PG PG G G G G +GS PGPPG F Sbjct: 870 QGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGF 911 Score = 77.0 bits (188), Expect = 3e-14 Identities = 44/94 (46%), Positives = 52/94 (55%), Gaps = 11/94 (11%) Query: 246 PGPPGLPGGQGPPGSPG------PKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299 PG PGL G +G PG PG +G GF G+ G PG G +G G MGP P + Sbjct: 969 PGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGP-PGV----P 1023 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G +G +G PG PG G+ GE G GP GS GPPG Sbjct: 1024 GPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPG 1057 Score = 77.0 bits (188), Expect = 3e-14 Identities = 42/99 (42%), Positives = 48/99 (48%), Gaps = 2/99 (2%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 G+ L ++ GP GL G +G PG G G G G+ G G PGP G G GP Sbjct: 1186 GEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKS 1245 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 KQG +G G GA G G GE G PG G PG PG Sbjct: 1246 G--KQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPG 1282 Score = 77.0 bits (188), Expect = 3e-14 Identities = 44/100 (44%), Positives = 52/100 (52%), Gaps = 11/100 (11%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQP------GPRGSMGPMG-PSPDLSHI 297 +PG PG PG GP GS G G G PG G G+P G +G +GP+G P P Sbjct: 1271 VPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKG 1330 Query: 298 KQGR----RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +QG GP GPPG G G +G+RG PG G PG G Sbjct: 1331 EQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEG 1370 Score = 75.1 bits (183), Expect = 1e-13 Identities = 41/98 (41%), Positives = 51/98 (52%), Gaps = 11/98 (11%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGPSPDLSHIKQGRRG 303 GPPG G +G G PG +G PG G PG G+ PG G GP GP D+ +G +G Sbjct: 1502 GPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGF--KGIQG 1559 Query: 304 PVGPPGAPGRDGSKGE------RGAPGPRGSPGPPGSF 335 P GPPG G++G G G PGP+G G G + Sbjct: 1560 PRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDW 1597 Score = 68.9 bits (167), Expect = 8e-12 Identities = 42/105 (40%), Positives = 47/105 (44%), Gaps = 20/105 (19%) Query: 245 LPGPPGLPG-----GQ-------GPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292 + GP GLPG GQ G PG GP G G PG+ G PG GP G G G Sbjct: 1440 IAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESG--- 1496 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 G+ GP G G GR G G +G PG +G PG G F Sbjct: 1497 -----LPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGF 1536 Score = 68.2 bits (165), Expect = 1e-11 Identities = 39/99 (39%), Positives = 50/99 (50%), Gaps = 11/99 (11%) Query: 245 LPGPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIK 298 LPG G+ G GP G+PG +G PG G GP G G +G G P PD H + Sbjct: 1160 LPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRG--DPGPDGEHGE 1217 Query: 299 QGRRGPV---GPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 +G+ G + GPPG PG G +G G G +G G G+ Sbjct: 1218 KGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGA 1256 Score = 48.1 bits (113), Expect = 1e-05 Identities = 23/48 (47%), Positives = 27/48 (56%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG 280 I G + + LPGP G G +G G GP+G PG G PGPPG PG Sbjct: 1572 IVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPG 1619 Score = 42.0 bits (97), Expect = 0.001 Identities = 23/50 (46%), Positives = 25/50 (50%), Gaps = 11/50 (22%) Query: 285 MGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 MGP GP +G G PG PG G G GA GPRG PGP G+ Sbjct: 624 MGPPGP-----------KGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGN 662 Score = 38.1 bits (87), Expect = 0.014 Identities = 18/36 (50%), Positives = 19/36 (52%) Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSF 335 G GP G G PG G G G PG RG GPPG + Sbjct: 625 GPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPY 660 >gi|38570075 collagen, type XXV, alpha 1 isoform 1 [Homo sapiens] Length = 654 Score = 101 bits (251), Expect = 1e-21 Identities = 46/88 (52%), Positives = 55/88 (62%), Gaps = 8/88 (9%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG PG +GPPG G G G PG+PG PG+PG +G MGP+GP G++G + Sbjct: 197 PGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGP--------PGQKGSI 248 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG PG +G KGE G PG G G PG Sbjct: 249 GAPGIPGMNGQKGEPGLPGAVGQNGIPG 276 Score = 86.3 bits (212), Expect = 5e-17 Identities = 52/118 (44%), Positives = 56/118 (47%), Gaps = 12/118 (10%) Query: 228 DLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF------PGMPGPPGQPGP 281 D G G K + PG G PG G PG PG KG PGF PG+PG PG G Sbjct: 304 DPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGE 363 Query: 282 RGSMGPMG------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 RG GP G P KQG G GP G+ G G KG+ GA GPRG PG G Sbjct: 364 RGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKG 421 Score = 86.3 bits (212), Expect = 5e-17 Identities = 53/117 (45%), Positives = 64/117 (54%), Gaps = 12/117 (10%) Query: 222 LPNNAADLGKY-ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG 280 L + D+G +TG+K LPG G+ G +G G PGP+G P G PGPPG G Sbjct: 480 LKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQG-PSIIGPPGPPGPHG 538 Query: 281 PRGSMGPMG-PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGA---PGPRGSPGPPG 333 P G MGP G P P +G GP+GP G G G +GE+GA PGPRG G PG Sbjct: 539 PPGPMGPHGLPGP------KGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPG 589 Score = 85.9 bits (211), Expect = 6e-17 Identities = 46/103 (44%), Positives = 52/103 (50%), Gaps = 16/103 (15%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH---------I 297 GPPG G +G G GP G PG G PGP G G +G GP P ++H I Sbjct: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLI 182 Query: 298 K-------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 K QG+ GP GPPG PG G G+ G GPRG PG PG Sbjct: 183 KRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPG 225 Score = 83.6 bits (205), Expect = 3e-16 Identities = 45/95 (47%), Positives = 53/95 (55%), Gaps = 16/95 (16%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GPPG PG QG G G +GSPG PGM G G G +G MG G + G +G +G Sbjct: 449 GPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMT--------GEKGGIG 500 Query: 307 PPGAPGRDGSKGER---GAPGPR-----GSPGPPG 333 PG PG +G KGE+ G PGP+ G PGPPG Sbjct: 501 LPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPG 535 Score = 80.9 bits (198), Expect = 2e-15 Identities = 48/118 (40%), Positives = 51/118 (43%), Gaps = 38/118 (32%) Query: 247 GPPGLPGGQGPPGSPGPKGSPG-------FP-----------------------GMPGPP 276 GPPG PG QGPPG G KG G FP G GPP Sbjct: 138 GPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPP 197 Query: 277 GQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G PGP G GP G + G+ GP G PG PG G GE+G GP G PG GS Sbjct: 198 GPPGPPGPRGPPGDT--------GKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGS 247 Score = 80.9 bits (198), Expect = 2e-15 Identities = 48/101 (47%), Positives = 50/101 (49%), Gaps = 16/101 (15%) Query: 246 PGPPGLPGGQGPPGSPGP---KGSPGFPGMP--------GPPGQPGPRGSMGPMGPSPDL 294 PG G GG G PG PG KG G GMP GPPG PGP G GPMGP Sbjct: 490 PGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGP---- 545 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSF 335 H G +G GP G G G KGERG G G PGP G + Sbjct: 546 -HGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPY 585 Score = 78.6 bits (192), Expect = 1e-14 Identities = 42/106 (39%), Positives = 50/106 (47%), Gaps = 18/106 (16%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-------- 297 PG PG+ G +G PG PG G G PG G PG+ G +G G GP D Sbjct: 251 PGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAA 310 Query: 298 ----------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 + G++G G PG PG G KGE G GP+G PG PG Sbjct: 311 GIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPG 356 Score = 78.2 bits (191), Expect = 1e-14 Identities = 42/87 (48%), Positives = 48/87 (55%), Gaps = 7/87 (8%) Query: 250 GLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PDLSHIKQGRRGPVGP 307 G+ G G G PG KG PG PG+PG PG G G +GP G P L K G RG GP Sbjct: 311 GIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTK-GERGEAGP 369 Query: 308 PGAPGRDGSKGERGAPGPRGSPGPPGS 334 PG G +GE GAPGP+G G G+ Sbjct: 370 PGR----GERGEPGAPGPKGKQGESGT 392 Score = 77.0 bits (188), Expect = 3e-14 Identities = 42/87 (48%), Positives = 45/87 (51%), Gaps = 5/87 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GPPG PG GPPG GP G PG G GP G GP G G G + + G RGP G Sbjct: 529 GPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMG--EPGPRGPYG 586 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 PG+DG G G PGPRG G G Sbjct: 587 L---PGKDGEPGLDGFPGPRGEKGDLG 610 Score = 75.9 bits (185), Expect = 6e-14 Identities = 42/95 (44%), Positives = 46/95 (48%), Gaps = 10/95 (10%) Query: 247 GPPGLPGGQGPPGSPG---PKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303 GPPG G G PG PG KG PG PG G G PGP+G G G D + G +G Sbjct: 240 GPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAG--ENGPKG 297 Query: 304 PVGPPGAPGRD-----GSKGERGAPGPRGSPGPPG 333 G G PG G GE G PG +G PG PG Sbjct: 298 DTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPG 332 Score = 73.6 bits (179), Expect = 3e-13 Identities = 44/100 (44%), Positives = 47/100 (47%), Gaps = 14/100 (14%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPG------------QPGPRGSMGPMGPSPD 293 PGP G PG GP G PGPKG+ G G GP G +PGPRG G P D Sbjct: 534 PGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGL--PGKD 591 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP G G G G KG RG G +G PG PG Sbjct: 592 GEPGLDGFPGPRGEKGDLGEKGEKGFRGVKGEKGEPGQPG 631 Score = 72.4 bits (176), Expect = 7e-13 Identities = 42/100 (42%), Positives = 47/100 (47%), Gaps = 21/100 (21%) Query: 246 PGPPGLPGGQG---------PPGSPGPKGSPGFPGMPGPPGQPGPRGSM---GPMGPSPD 293 PG PG+ G QG PG G KG G PG+PG G G +G GP GPS Sbjct: 469 PGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPS-- 526 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP GPPG G G G G PGP+G+ GP G Sbjct: 527 -------IIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMG 559 Score = 63.9 bits (154), Expect = 2e-10 Identities = 50/165 (30%), Positives = 60/165 (36%), Gaps = 76/165 (46%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP-----------------PGQPGPRG---- 283 LPG PGLPG +G PG GP+G PG PG+PG PG PGP+G Sbjct: 330 LPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKGKQGE 389 Query: 284 --------------------SMGPMGP---------------SPDLSHIKQ--------G 300 + GP GP + +L Q G Sbjct: 390 SGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTG 449 Query: 301 RRGPVGP------------PGAPGRDGSKGERGAPGPRGSPGPPG 333 GP GP PG PG DG +G +G+ G G PG G Sbjct: 450 PPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTG 494 Score = 59.3 bits (142), Expect = 6e-09 Identities = 37/88 (42%), Positives = 41/88 (46%), Gaps = 15/88 (17%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G G PG +GP G PG G PG G PGP G+ G G G G +G +G G Sbjct: 574 GAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKG--------FRGVKGEKG 625 Query: 307 PPGAPGRDGSKGERGAP---GPRGSPGP 331 PG PG DG AP GP G P P Sbjct: 626 EPGQPGLDG----LDAPCQLGPDGLPMP 649 Score = 42.0 bits (97), Expect = 0.001 Identities = 23/51 (45%), Positives = 25/51 (49%), Gaps = 3/51 (5%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGP---PGQPGPRGSMGPMGPSPD 293 PG G PG +G G G KG GF G+ G PGQPG G P PD Sbjct: 594 PGLDGFPGPRGEKGDLGEKGEKGFRGVKGEKGEPGQPGLDGLDAPCQLGPD 644 Score = 32.0 bits (71), Expect = 1.0 Identities = 14/27 (51%), Positives = 16/27 (59%), Gaps = 3/27 (11%) Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 P G PG+ G +G RG GP PG PG Sbjct: 121 PAGPPGKRGKRGRRGESGP---PGQPG 144 >gi|38570073 collagen, type XXV, alpha 1 isoform 2 [Homo sapiens] Length = 642 Score = 101 bits (251), Expect = 1e-21 Identities = 46/88 (52%), Positives = 55/88 (62%), Gaps = 8/88 (9%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG PG +GPPG G G G PG+PG PG+PG +G MGP+GP G++G + Sbjct: 197 PGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGP--------PGQKGSI 248 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG PG +G KGE G PG G G PG Sbjct: 249 GAPGIPGMNGQKGEPGLPGAVGQNGIPG 276 Score = 86.3 bits (212), Expect = 5e-17 Identities = 52/118 (44%), Positives = 56/118 (47%), Gaps = 12/118 (10%) Query: 228 DLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF------PGMPGPPGQPGP 281 D G G K + PG G PG G PG PG KG PGF PG+PG PG G Sbjct: 304 DPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGE 363 Query: 282 RGSMGPMG------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 RG GP G P KQG G GP G+ G G KG+ GA GPRG PG G Sbjct: 364 RGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKG 421 Score = 86.3 bits (212), Expect = 5e-17 Identities = 53/117 (45%), Positives = 64/117 (54%), Gaps = 12/117 (10%) Query: 222 LPNNAADLGKY-ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG 280 L + D+G +TG+K LPG G+ G +G G PGP+G P G PGPPG G Sbjct: 480 LKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQG-PSIIGPPGPPGPHG 538 Query: 281 PRGSMGPMG-PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGA---PGPRGSPGPPG 333 P G MGP G P P +G GP+GP G G G +GE+GA PGPRG G PG Sbjct: 539 PPGPMGPHGLPGP------KGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPG 589 Score = 85.9 bits (211), Expect = 6e-17 Identities = 46/103 (44%), Positives = 52/103 (50%), Gaps = 16/103 (15%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH---------I 297 GPPG G +G G GP G PG G PGP G G +G GP P ++H I Sbjct: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLI 182 Query: 298 K-------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 K QG+ GP GPPG PG G G+ G GPRG PG PG Sbjct: 183 KRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPG 225 Score = 84.7 bits (208), Expect = 1e-16 Identities = 46/93 (49%), Positives = 50/93 (53%), Gaps = 5/93 (5%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPG---MPGPPGQPGPRGSMGPMGPSPDLSHI-KQG 300 +PGP G P GPPG PGP G PG G +PGP G GP G GP GP + G Sbjct: 519 MPGPQG-PSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMG 577 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP GP G PG+DG G G PGPRG G G Sbjct: 578 EPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLG 610 Score = 83.6 bits (205), Expect = 3e-16 Identities = 45/95 (47%), Positives = 53/95 (55%), Gaps = 16/95 (16%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GPPG PG QG G G +GSPG PGM G G G +G MG G + G +G +G Sbjct: 449 GPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMT--------GEKGGIG 500 Query: 307 PPGAPGRDGSKGER---GAPGPR-----GSPGPPG 333 PG PG +G KGE+ G PGP+ G PGPPG Sbjct: 501 LPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPG 535 Score = 80.9 bits (198), Expect = 2e-15 Identities = 48/118 (40%), Positives = 51/118 (43%), Gaps = 38/118 (32%) Query: 247 GPPGLPGGQGPPGSPGPKGSPG-------FP-----------------------GMPGPP 276 GPPG PG QGPPG G KG G FP G GPP Sbjct: 138 GPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPP 197 Query: 277 GQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G PGP G GP G + G+ GP G PG PG G GE+G GP G PG GS Sbjct: 198 GPPGPPGPRGPPGDT--------GKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGS 247 Score = 80.9 bits (198), Expect = 2e-15 Identities = 48/101 (47%), Positives = 50/101 (49%), Gaps = 16/101 (15%) Query: 246 PGPPGLPGGQGPPGSPGP---KGSPGFPGMP--------GPPGQPGPRGSMGPMGPSPDL 294 PG G GG G PG PG KG G GMP GPPG PGP G GPMGP Sbjct: 490 PGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGP---- 545 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSF 335 H G +G GP G G G KGERG G G PGP G + Sbjct: 546 -HGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPY 585 Score = 78.6 bits (192), Expect = 1e-14 Identities = 42/106 (39%), Positives = 50/106 (47%), Gaps = 18/106 (16%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-------- 297 PG PG+ G +G PG PG G G PG G PG+ G +G G GP D Sbjct: 251 PGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAA 310 Query: 298 ----------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 + G++G G PG PG G KGE G GP+G PG PG Sbjct: 311 GIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPG 356 Score = 78.2 bits (191), Expect = 1e-14 Identities = 42/87 (48%), Positives = 48/87 (55%), Gaps = 7/87 (8%) Query: 250 GLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PDLSHIKQGRRGPVGP 307 G+ G G G PG KG PG PG+PG PG G G +GP G P L K G RG GP Sbjct: 311 GIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTK-GERGEAGP 369 Query: 308 PGAPGRDGSKGERGAPGPRGSPGPPGS 334 PG G +GE GAPGP+G G G+ Sbjct: 370 PGR----GERGEPGAPGPKGKQGESGT 392 Score = 75.9 bits (185), Expect = 6e-14 Identities = 42/95 (44%), Positives = 46/95 (48%), Gaps = 10/95 (10%) Query: 247 GPPGLPGGQGPPGSPG---PKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303 GPPG G G PG PG KG PG PG G G PGP+G G G D + G +G Sbjct: 240 GPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAG--ENGPKG 297 Query: 304 PVGPPGAPGRD-----GSKGERGAPGPRGSPGPPG 333 G G PG G GE G PG +G PG PG Sbjct: 298 DTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPG 332 Score = 72.4 bits (176), Expect = 7e-13 Identities = 42/100 (42%), Positives = 47/100 (47%), Gaps = 21/100 (21%) Query: 246 PGPPGLPGGQG---------PPGSPGPKGSPGFPGMPGPPGQPGPRGSM---GPMGPSPD 293 PG PG+ G QG PG G KG G PG+PG G G +G GP GPS Sbjct: 469 PGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPS-- 526 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP GPPG G G G G PGP+G+ GP G Sbjct: 527 -------IIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMG 559 Score = 63.9 bits (154), Expect = 2e-10 Identities = 50/165 (30%), Positives = 60/165 (36%), Gaps = 76/165 (46%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP-----------------PGQPGPRG---- 283 LPG PGLPG +G PG GP+G PG PG+PG PG PGP+G Sbjct: 330 LPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKGKQGE 389 Query: 284 --------------------SMGPMGP---------------SPDLSHIKQ--------G 300 + GP GP + +L Q G Sbjct: 390 SGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTG 449 Query: 301 RRGPVGP------------PGAPGRDGSKGERGAPGPRGSPGPPG 333 GP GP PG PG DG +G +G+ G G PG G Sbjct: 450 PPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTG 494 Score = 47.4 bits (111), Expect = 2e-05 Identities = 22/46 (47%), Positives = 24/46 (52%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292 G G PG +GP G PG G PG G PGP G+ G G G SP Sbjct: 574 GAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKVTSP 619 Score = 32.0 bits (71), Expect = 1.0 Identities = 14/27 (51%), Positives = 16/27 (59%), Gaps = 3/27 (11%) Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 P G PG+ G +G RG GP PG PG Sbjct: 121 PAGPPGKRGKRGRRGESGP---PGQPG 144 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 99.8 bits (247), Expect = 4e-21 Identities = 56/125 (44%), Positives = 65/125 (52%), Gaps = 15/125 (12%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282 P D G G + LA + GP G+PG +G G+ GP G+ GFPG G G PGP Sbjct: 866 PGQKGDAGS--PGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPA 923 Query: 283 GSMGPMGP--------SPDL-----SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSP 329 G+ GP GP P L SH + G RGP GPPG PG G GE G PGP G P Sbjct: 924 GAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPP 983 Query: 330 GPPGS 334 GP G+ Sbjct: 984 GPAGT 988 Score = 99.4 bits (246), Expect = 5e-21 Identities = 51/103 (49%), Positives = 57/103 (55%), Gaps = 20/103 (19%) Query: 246 PGPPGLPGGQGPPGSPGPKGS---------------PGFPGMPGPPGQPGPRGSMGPMGP 290 PG G PG GPPGSPGP+GS PGF G GP G+PGP G GP+GP Sbjct: 437 PGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGP 496 Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 + +G+RGP G PG G G GERGAPG RG PG G Sbjct: 497 PGE-----EGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDG 534 Score = 92.0 bits (227), Expect = 8e-19 Identities = 52/106 (49%), Positives = 57/106 (53%), Gaps = 14/106 (13%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 G++ + LPGP G G +GP GS GPKGS G PG PG PG PG RG G G Sbjct: 525 GNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPG----- 579 Query: 295 SHIKQGRRGPVGPPGAPGRD------GSKGERGAPGPRGSPGPPGS 334 QG G +GP GAPG D GS G RG PG G PGP GS Sbjct: 580 ---VQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGS 622 Score = 90.9 bits (224), Expect = 2e-18 Identities = 50/107 (46%), Positives = 56/107 (52%), Gaps = 19/107 (17%) Query: 246 PGPPGLPGGQGPPGSPGP---------KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL-S 295 PGP GLPG QG PG+PGP +G PG G GPPG+ G RG GP GP D Sbjct: 1073 PGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGD 1132 Query: 296 HIKQGRRGPVGP---------PGAPGRDGSKGERGAPGPRGSPGPPG 333 H +G RG G PG PG +G +G G PGP G GPPG Sbjct: 1133 HGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPG 1179 Score = 90.5 bits (223), Expect = 2e-18 Identities = 48/91 (52%), Positives = 50/91 (54%), Gaps = 8/91 (8%) Query: 246 PGP---PGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 PGP PGLPG G G+PG KG G PG GPPG GP GS GP G S QG R Sbjct: 410 PGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQG-----STGPQGIR 464 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G PG PG G G +G PGP G GP G Sbjct: 465 GQPGDPGVPGFKGEAGPKGEPGPHGIQGPIG 495 Score = 90.5 bits (223), Expect = 2e-18 Identities = 46/88 (52%), Positives = 50/88 (56%), Gaps = 1/88 (1%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP-SPDLSHIKQGRRGPV 305 G G G QGP G PG KG PG PG G G PGP+G G GP P+ +G RG Sbjct: 843 GAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQ 902 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPGA G GS G G PGP G+PGP G Sbjct: 903 GPPGATGFPGSAGRVGPPGPAGAPGPAG 930 Score = 89.7 bits (221), Expect = 4e-18 Identities = 49/97 (50%), Positives = 53/97 (54%), Gaps = 11/97 (11%) Query: 247 GPPGLPGGQGPPGSPGPKG------SPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300 G PG G G PG PGP G S GFPG PG G+ GP G+ GP GP + G Sbjct: 351 GAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRG--ETG 408 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSP---GPPGS 334 GPVG PG PG G+ G GA GP GSP GPPGS Sbjct: 409 PPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGS 445 Score = 89.7 bits (221), Expect = 4e-18 Identities = 51/108 (47%), Positives = 54/108 (50%), Gaps = 19/108 (17%) Query: 246 PGPPGLPGGQ---------GPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296 PG GLPG + GP GSPGP G+PG G PG G PG RG G GP D Sbjct: 722 PGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGG 781 Query: 297 I----------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 I G RG GP G PG G GE+G PGPRG GPPGS Sbjct: 782 IGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGS 829 Score = 89.4 bits (220), Expect = 5e-18 Identities = 46/92 (50%), Positives = 52/92 (56%), Gaps = 5/92 (5%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG PGL G +G G GPKG G PG G G GP G+MGP+GP G RG + Sbjct: 293 PGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRG-----MPGERGRL 347 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 GP GAPG+ G+ G G PGP G G PGS F Sbjct: 348 GPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGF 379 Score = 89.4 bits (220), Expect = 5e-18 Identities = 47/87 (54%), Positives = 51/87 (58%), Gaps = 8/87 (9%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G G G QG PG PGP G G G+PGP GPRG GP+GPS K+G GP+G Sbjct: 1143 GHRGFTGLQGLPGPPGPNGEQGSAGIPGP---FGPRGPPGPVGPSG-----KEGNPGPLG 1194 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 P G PG GS GE G GP G PGPPG Sbjct: 1195 PIGPPGVRGSVGEAGPEGPPGEPGPPG 1221 Score = 85.9 bits (211), Expect = 6e-17 Identities = 52/134 (38%), Positives = 57/134 (42%), Gaps = 46/134 (34%) Query: 246 PGPPGLPGGQGPPGSPGPKGSP---------GFPGMPGPPGQPGP--------------- 281 PGP G PG QGP G GPKG P G PG+PG PG PGP Sbjct: 131 PGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRP 190 Query: 282 ---------------------RGSMGPMGP-SPDLSHIKQGRRGPVGPPGAPGRDGSKGE 319 GS+GP+GP P +QG GP GPPG PG G G Sbjct: 191 FSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGP 250 Query: 320 RGAPGPRGSPGPPG 333 G+ GP G PG PG Sbjct: 251 IGSRGPEGPPGKPG 264 Score = 85.9 bits (211), Expect = 6e-17 Identities = 51/124 (41%), Positives = 65/124 (52%), Gaps = 12/124 (9%) Query: 215 LKQKIALLPNNAADLG----KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFP 270 L ++ L+P + +G + + G + A T PG PG PG GP GS GP+G PG P Sbjct: 204 LGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKP 263 Query: 271 GMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPG 330 G G PG+ G G +G G SP G RG G PG PG G +G +G GP+G G Sbjct: 264 GEDGEPGRNGNPGEVGFAG-SP-------GARGFPGAPGLPGLKGHRGHKGLEGPKGEVG 315 Query: 331 PPGS 334 PGS Sbjct: 316 APGS 319 Score = 85.1 bits (209), Expect = 1e-16 Identities = 47/101 (46%), Positives = 52/101 (51%), Gaps = 13/101 (12%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP----SPDLSHIKQGR- 301 GP G PG GPPG G +G+PG G PG G PGP+G+ G GP P S GR Sbjct: 504 GPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRP 563 Query: 302 --------RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 RG G PG G +G G GAPG G PGPPGS Sbjct: 564 GEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGS 604 Score = 84.7 bits (208), Expect = 1e-16 Identities = 46/100 (46%), Positives = 50/100 (50%), Gaps = 5/100 (5%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 G LA GPPG G QG PG PGP G G PG G PG PG G +GP G + Sbjct: 657 GPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGN- 715 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G RG G G PG G G G GP+GSPGP G+ Sbjct: 716 ----PGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGT 751 Score = 84.3 bits (207), Expect = 2e-16 Identities = 44/102 (43%), Positives = 55/102 (53%), Gaps = 13/102 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQP---------GPRGSMGPMGPSPDLSH 296 PGP G G +G G PG +G G PG+PGP G P G +G GP+GP Sbjct: 983 PGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGP 1042 Query: 297 I-KQGRRGPVGPPGAPGRDGS---KGERGAPGPRGSPGPPGS 334 + + G GP G G PGRDG+ +G+RG PGP G PG G+ Sbjct: 1043 VGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGA 1084 Score = 83.2 bits (204), Expect = 4e-16 Identities = 51/116 (43%), Positives = 55/116 (47%), Gaps = 15/116 (12%) Query: 222 LPNNAADLGKY----ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPG 277 LP A GK TGDK PGP G PG GP G PGP+G G G PG G Sbjct: 1009 LPGPAGTPGKVGPTGATGDKGP------PGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDG 1062 Query: 278 QPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G RG G GP+ G +G G PG G G G+RG PG RG GPPG Sbjct: 1063 AVGERGDRGDPGPAG-----LPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPG 1113 Score = 82.8 bits (203), Expect = 5e-16 Identities = 53/116 (45%), Positives = 55/116 (47%), Gaps = 26/116 (22%) Query: 246 PGPPGLPGG---------QGPPGSPGPKGSPGFPGMPGPPG------QPGPRGSMGPMGP 290 PG PGLPG QGP G GP G+PG G PGPPG QPG G GP G Sbjct: 563 PGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGS 622 Query: 291 SPDLSHIKQGRRGPVGPPG---APGRDGSKGERGAPGP------RGSPGPPGSFDF 337 S D K G G G PG APG+DG G G GP RG GPPG F Sbjct: 623 SGDPG--KPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGF 676 Score = 82.8 bits (203), Expect = 5e-16 Identities = 45/103 (43%), Positives = 49/103 (47%), Gaps = 16/103 (15%) Query: 247 GPPGLPGGQG------------PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----P 290 GPPGL G G PPG PG KG PG G PGP G PGP G+ G G P Sbjct: 939 GPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMP 998 Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP G PG G G+ G++G PGP G PG G Sbjct: 999 GQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNG 1041 Score = 82.4 bits (202), Expect = 7e-16 Identities = 42/87 (48%), Positives = 45/87 (51%), Gaps = 8/87 (9%) Query: 251 LPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGA 310 +PG GP G GP+G G G GP G PG G GPMGP G RGP GPPG Sbjct: 211 MPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPI--------GSRGPEGPPGK 262 Query: 311 PGRDGSKGERGAPGPRGSPGPPGSFDF 337 PG DG G G PG G G PG+ F Sbjct: 263 PGEDGEPGRNGNPGEVGFAGSPGARGF 289 Score = 82.4 bits (202), Expect = 7e-16 Identities = 44/93 (47%), Positives = 51/93 (54%), Gaps = 4/93 (4%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLS--HIKQGR 301 PG GLPG +G G PG G G G+PG G PG G +GP GP P L+ +QG Sbjct: 611 PGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGP 670 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 GP G G PG G GE G PG +G PG PG+ Sbjct: 671 PGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGA 703 Score = 82.0 bits (201), Expect = 9e-16 Identities = 43/94 (45%), Positives = 49/94 (52%), Gaps = 11/94 (11%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGP------PGQPGPRGSMGPMGPSPDLSHIKQ 299 PG G PG GPPG G G G GMPG PG PGP G+ G +GP+ Sbjct: 971 PGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTG-----AT 1025 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G +GP GP G PG +G GE G GP G+ G PG Sbjct: 1026 GDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPG 1059 Score = 82.0 bits (201), Expect = 9e-16 Identities = 48/117 (41%), Positives = 51/117 (43%), Gaps = 11/117 (9%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 GD+ + G GLPG GP G G G PG G GPPG GP G G GP Sbjct: 1137 GDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGP---- 1192 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITE 351 GP+GPPG G G G G PG G PGPPG L L DI E Sbjct: 1193 -------LGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDE 1242 Score = 81.3 bits (199), Expect = 1e-15 Identities = 47/97 (48%), Positives = 54/97 (55%), Gaps = 7/97 (7%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGF---PGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQG 300 LPGP G PG GP G+ G KG PG PG GP G+PGP G G G P D + ++G Sbjct: 1009 LPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERG 1068 Query: 301 RRGPVGP---PGAPGRDGSKGERGAPGPRGSPGPPGS 334 RG GP PG+ G G+ G GAPG G G PGS Sbjct: 1069 DRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGS 1105 Score = 80.9 bits (198), Expect = 2e-15 Identities = 45/95 (47%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Query: 240 ASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG-PMGPSPDLSHIK 298 A N +PG G PG G G GP G PG G G G PGP G G P P P K Sbjct: 632 AGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGK 691 Query: 299 QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G +G G PGA G G +GERG PG RG PG G Sbjct: 692 PGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITG 726 Score = 80.5 bits (197), Expect = 3e-15 Identities = 46/104 (44%), Positives = 54/104 (51%), Gaps = 4/104 (3%) Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSP 292 TG + + PG PG G GP G PGP G G G PG G+ GPRG G +G P P Sbjct: 458 TGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGP 517 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGER---GAPGPRGSPGPPG 333 G RG G G PG G++GER G+ GP+GS G PG Sbjct: 518 VGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPG 561 Score = 80.1 bits (196), Expect = 3e-15 Identities = 47/117 (40%), Positives = 56/117 (47%), Gaps = 16/117 (13%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSP---GFPGMPGPPGQPGPRGSMGPMG 289 + G + L N + GP G G G PG G G P G G PG G PGP+GS G G Sbjct: 568 LPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPG 627 Query: 290 PSPDLSHI----------KQGRRGPVGPPGAPGRDGSKGERGAPGP---RGSPGPPG 333 + + K G GP GP G PG G +GE+G PGP +G PGPPG Sbjct: 628 KPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPG 684 Score = 80.1 bits (196), Expect = 3e-15 Identities = 53/121 (43%), Positives = 55/121 (45%), Gaps = 16/121 (13%) Query: 219 IALLPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGP---KGSPGFPGMPGP 275 IA P D G G+K G GLPG GPPG GP KG PG G+ GP Sbjct: 769 IAGTPGPKGDRGGI--GEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGP 826 Query: 276 PGQ---PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPP 332 PG PG RG GP G G GP GP G PG G GE G G GSPGP Sbjct: 827 PGSRGNPGSRGENGPTG--------AVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQ 878 Query: 333 G 333 G Sbjct: 879 G 879 Score = 79.7 bits (195), Expect = 4e-15 Identities = 48/118 (40%), Positives = 54/118 (45%), Gaps = 38/118 (32%) Query: 246 PGPPGLPGGQGPPGS---PGPKGSPGFPGMPG---------------------------P 275 PGPPG G +G PGS PGPKGS G PG PG P Sbjct: 599 PGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGP 658 Query: 276 PGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 PG G RG GP GP+ G +G GPPG PG G G++G PG G+ GP G Sbjct: 659 PGLAGERGEQGPPGPT--------GFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLG 708 Score = 75.5 bits (184), Expect = 8e-14 Identities = 45/98 (45%), Positives = 54/98 (55%), Gaps = 13/98 (13%) Query: 247 GPPGLPGGQGPPGSPG------PKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQ 299 GP G G GP G PG P+G+PG G G PG+PGP MGP+G P Sbjct: 327 GPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGP---MGPLGIPGSSGFPGNP 383 Query: 300 GRRGPVGPPGAPGRDGSKGER---GAPGPRGSPGPPGS 334 G +G GP GA G +G +G+R G PGP GSPG PG+ Sbjct: 384 GMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGA 421 Score = 73.9 bits (180), Expect = 2e-13 Identities = 47/132 (35%), Positives = 55/132 (41%), Gaps = 43/132 (32%) Query: 245 LPGPPGLPGGQGPPG---------------------SPGPKGSPGFPGMPGPPGQPG--- 280 LPGPPG PG G PG +PG +G PG G+PG G G Sbjct: 679 LPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHG 738 Query: 281 ---PRGSMGPMGPSPDL----------------SHIKQGRRGPVGPPGAPGRDGSKGERG 321 P+GS GP G D + +G RG +G GA G G+ G RG Sbjct: 739 PDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARG 798 Query: 322 APGPRGSPGPPG 333 PGP G PGP G Sbjct: 799 LPGPLGPPGPAG 810 Score = 67.4 bits (163), Expect = 2e-11 Identities = 38/86 (44%), Positives = 42/86 (48%), Gaps = 12/86 (13%) Query: 252 PGGQGPPGSPGPKGSPGFPGM----PGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGP 307 PGG G KG G PG+ G G+PGP G G GP +G RGP G Sbjct: 100 PGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGP--------RGERGPKGR 151 Query: 308 PGAPGRDGSKGERGAPGPRGSPGPPG 333 PG G G GE G PG G+PGPPG Sbjct: 152 PGPRGPQGIDGEPGVPGQPGAPGPPG 177 Score = 64.3 bits (155), Expect = 2e-10 Identities = 47/131 (35%), Positives = 51/131 (38%), Gaps = 44/131 (33%) Query: 247 GPPGL----PGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG---------------- 286 G PGL G +G PG GP GS G G GP G+PGPRG G Sbjct: 116 GEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGP 175 Query: 287 ---PMGPSPD-LSH--------------------IKQGRRGPVGPPGAPGRDGSKGERGA 322 P P PD LS + G GPVGP G G G +G G Sbjct: 176 PGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGP 235 Query: 323 PGPRGSPGPPG 333 GP G PG PG Sbjct: 236 TGPPGEPGDPG 246 >gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] Length = 1690 Score = 99.0 bits (245), Expect = 7e-21 Identities = 49/91 (53%), Positives = 49/91 (53%), Gaps = 8/91 (8%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG GLPG GPPG PGP G GFPG G GQ GP G GP GP G GP Sbjct: 1291 PGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGP--------HGFPGPP 1342 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPGSFD 336 G G PG G KG G PGPRG PGPP D Sbjct: 1343 GEKGLPGPPGRKGPTGLPGPRGEPGPPADVD 1373 Score = 98.2 bits (243), Expect = 1e-20 Identities = 52/104 (50%), Positives = 59/104 (56%), Gaps = 13/104 (12%) Query: 246 PGPPGLPGGQGP------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPD-----L 294 PGPPGLPG QG PG G KG PG PG GPPG PG G+ GP G + Sbjct: 502 PGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVV 561 Query: 295 SHIK--QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFD 336 S +K +G RGP GPPG PG+ GS G G G +G PGPPG + Sbjct: 562 SRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHE 605 Score = 89.0 bits (219), Expect = 7e-18 Identities = 49/111 (44%), Positives = 59/111 (53%), Gaps = 21/111 (18%) Query: 245 LPG-PPGLPGGQGPPGSPGPKGSPGFPGMPGPP------GQPGPRGSMGPMGP------- 290 +PG P PG G PGSPG G+PG G+PG G PGP+G G +GP Sbjct: 424 IPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPK 483 Query: 291 ----SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAP---GPRGSPGPPGS 334 + L + G GP GPPG PGR GSKG+ G P G +G PGPPG+ Sbjct: 484 GEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGA 534 Score = 88.6 bits (218), Expect = 9e-18 Identities = 53/117 (45%), Positives = 57/117 (48%), Gaps = 29/117 (24%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-----------PSPDL 294 PG PG PG GPPG PG G PG G PG G PGPRG G G SP L Sbjct: 1117 PGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGL 1176 Query: 295 S--HIKQGRRG--------PVGPPGAPGRDGSKGERG--------APGPRGSPGPPG 333 + H +G++G VGPPG G G KGERG PGPRG GPPG Sbjct: 1177 NGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPG 1233 Score = 88.2 bits (217), Expect = 1e-17 Identities = 46/94 (48%), Positives = 52/94 (55%), Gaps = 9/94 (9%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-----PDLSHIKQ 299 +PGPPG +G PG PG G PG+PG PG PG G G +GP GP+ P L Sbjct: 820 VPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGL----P 875 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GR G GPPG PG G G+ G PGP G GP G Sbjct: 876 GRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRG 909 Score = 86.3 bits (212), Expect = 5e-17 Identities = 50/106 (47%), Positives = 50/106 (47%), Gaps = 19/106 (17%) Query: 247 GPPGLPGGQGP---PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-----K 298 GP G PG QGP PG PG KG PG PG GP G PGPRG GP D I Sbjct: 1325 GPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGA 1384 Query: 299 QGRRGPVGP-----------PGAPGRDGSKGERGAPGPRGSPGPPG 333 G RGP G PG G G G RG G GSPGPPG Sbjct: 1385 PGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPG 1430 Score = 85.9 bits (211), Expect = 6e-17 Identities = 50/105 (47%), Positives = 54/105 (51%), Gaps = 17/105 (16%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGF------------PGMPGPPGQPGPRGSMGPMGPSPD 293 PG G PG GPPG PG G GF PG PGPPG G G+ GP G D Sbjct: 1017 PGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGD 1076 Query: 294 -LSHI-KQGRRGPVGPPGAPGRDGSKGERGAP---GPRGSPGPPG 333 SH G +G G PG PG G+ GE+G P GPRGSPG PG Sbjct: 1077 PASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPG 1121 Score = 85.5 bits (210), Expect = 8e-17 Identities = 44/98 (44%), Positives = 56/98 (57%), Gaps = 7/98 (7%) Query: 245 LPGPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI---- 297 LPG PG PG +G PG+ PG KG PG GM G PG G RG+ G +GP D + Sbjct: 910 LPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIIS 969 Query: 298 KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSF 335 ++G G GPPG G G +G++G PG +G G PG + Sbjct: 970 QKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRY 1007 Score = 85.1 bits (209), Expect = 1e-16 Identities = 52/114 (45%), Positives = 56/114 (49%), Gaps = 27/114 (23%) Query: 247 GPPGLPGGQGPPGSPGPKG-------SPGFPGMPGPPGQPGPRGSMGPMG--PSPDLSHI 297 GPPG PG GPPG G G PG PG GPPG GPRG+ GP G S DL Sbjct: 1230 GPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRG 1289 Query: 298 KQGRRGPVGPPGAP---------------GRDGSKGERGAPGPRGS---PGPPG 333 + G G GPPG P G+DG KG G PGP+G PGPPG Sbjct: 1290 EPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPG 1343 Score = 84.7 bits (208), Expect = 1e-16 Identities = 48/98 (48%), Positives = 53/98 (54%), Gaps = 5/98 (5%) Query: 240 ASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP---PGQPGPRGSMGPMGPSPDLSH 296 AS+ PGP G PG G PG G G G PG+ GP PG+PGP GS GP G D H Sbjct: 1078 ASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGD--H 1135 Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G RG G G PG G +G+ G PGP G GP GS Sbjct: 1136 GMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGS 1173 Score = 84.0 bits (206), Expect = 2e-16 Identities = 49/113 (43%), Positives = 55/113 (48%), Gaps = 22/113 (19%) Query: 247 GPPGLPGGQGPPGSPGPKGSPG----------FPGMPGPPGQPGPRGSMG------PMGP 290 G PG PG +GP G PGP+G PG PG+PG PG GP G+MG P GP Sbjct: 1346 GLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGP 1405 Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERG------APGPRGSPGPPGSFDF 337 GRRG G PG+PG G KG+ G PGP G G PG F Sbjct: 1406 GCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGF 1458 Score = 83.2 bits (204), Expect = 4e-16 Identities = 48/114 (42%), Positives = 53/114 (46%), Gaps = 15/114 (13%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 GDK T +PG PGL G G PG PGP+G PG G G G PG G G +GP L Sbjct: 104 GDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPL 163 Query: 295 SH---------------IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 H +G +G G PG PG GS G G GP G PG PG Sbjct: 164 GHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPG 217 Score = 83.2 bits (204), Expect = 4e-16 Identities = 44/90 (48%), Positives = 49/90 (54%), Gaps = 1/90 (1%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG-PMGPSPDLSHIKQGRRG 303 LPG PG PG GPPG PG G G G+PGPPG GPRG G P P +G G Sbjct: 871 LPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPG 930 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG G G G+RG G +G+ GPPG Sbjct: 931 AKGEPGEKGMSGLPGDRGLRGAKGAIGPPG 960 Score = 82.4 bits (202), Expect = 7e-16 Identities = 47/104 (45%), Positives = 52/104 (50%), Gaps = 17/104 (16%) Query: 247 GPPGLPGGQGPPGS--PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 GPPG G GPPG PGP G G PG+PG PG GP G G G + + GR GP Sbjct: 619 GPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGP 678 Query: 305 ------------VGPPGAPGRDGSKGERGAPGPRGS---PGPPG 333 GP GAPG GS G +G PG G+ PGPPG Sbjct: 679 PGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPG 722 Score = 82.0 bits (201), Expect = 9e-16 Identities = 42/84 (50%), Positives = 48/84 (57%), Gaps = 8/84 (9%) Query: 253 GGQGPPGSPGPKGSPGFPGMPGP---PGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPG 309 G +GPPG PGP+G G G PGP G+ G RG GP G + D +G +GP G PG Sbjct: 62 GSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGD-----KGDKGPTGVPG 116 Query: 310 APGRDGSKGERGAPGPRGSPGPPG 333 PG DG G G PGPRG PG G Sbjct: 117 FPGLDGIPGHPGPPGPRGKPGMSG 140 Score = 81.3 bits (199), Expect = 1e-15 Identities = 50/132 (37%), Positives = 62/132 (46%), Gaps = 33/132 (25%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF------PGMPGPP----GQPGPRGS 284 G+ + S PG PG PG G PG G KG+PG PG GPP G+PG +G Sbjct: 963 GEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQ 1022 Query: 285 MGPMGP--SPDLSHIK-----------QGRRGPVGPPGAPGRDGSKGER----------G 321 GP GP P + ++ QG G GPPG G DG++G + G Sbjct: 1023 PGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFG 1082 Query: 322 APGPRGSPGPPG 333 PGP+G PG PG Sbjct: 1083 PPGPKGEPGSPG 1094 Score = 81.3 bits (199), Expect = 1e-15 Identities = 53/124 (42%), Positives = 61/124 (49%), Gaps = 19/124 (15%) Query: 226 AADLGKYITGDKVLASNTYLPGPPGLPG-----------GQ-GPPGSPGPKGSPGFP--- 270 + DL + GD L PGPPG PG GQ GP G PGP+G GFP Sbjct: 1283 SVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPP 1342 Query: 271 ---GMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRG 327 G+PGPPG+ GP G GP G + + R P G PGAPG G +G G PG RG Sbjct: 1343 GEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIP-GLPGAPGMRGPEGAMGLPGMRG 1401 Query: 328 SPGP 331 GP Sbjct: 1402 PSGP 1405 Score = 80.5 bits (197), Expect = 3e-15 Identities = 43/87 (49%), Positives = 45/87 (51%), Gaps = 11/87 (12%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GPPG G G PG GP+G PG PG GP G PG G GP +GR G G Sbjct: 768 GPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGP-----------KGREGHAG 816 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 PG PG G ERGAPG G PG PG Sbjct: 817 FPGVPGPPGHSCERGAPGIPGQPGLPG 843 Score = 80.5 bits (197), Expect = 3e-15 Identities = 51/137 (37%), Positives = 57/137 (41%), Gaps = 46/137 (33%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPP-----------------------GSPGPKGSPGFPG 271 G + L + +PGPPG+ G G P G PGP G PG G Sbjct: 1151 GPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKG 1210 Query: 272 MPGPPGQ-----PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGA----------PGRDGS 316 G PG PGPRG GP GP G GP GP GA PG G Sbjct: 1211 ERGDPGSPGISPPGPRGKKGPPGP--------PGSSGPPGPAGATGRAPKDIPDPGPPGD 1262 Query: 317 KGERGAPGPRGSPGPPG 333 +G G GPRG+PGPPG Sbjct: 1263 QGPPGPDGPRGAPGPPG 1279 Score = 80.1 bits (196), Expect = 3e-15 Identities = 50/114 (43%), Positives = 57/114 (50%), Gaps = 20/114 (17%) Query: 235 GDKVLASNTY--LPGPPGLPGGQGPPGSPGPKGSPGF---------PGMPGPPGQPGPRG 283 GD + + TY GPPG G GP G PGP+G+PG PG PG PGP G Sbjct: 663 GDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPG 722 Query: 284 SMGPMGPSPDLSHIKQGRRG--PVGPPGAPGRDGSKGERGAPGPR--GSPGPPG 333 G MG P G +G PVGPPG PG G G++G PG G GPPG Sbjct: 723 FRGDMG-DPGFG----GEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPG 771 Score = 80.1 bits (196), Expect = 3e-15 Identities = 46/101 (45%), Positives = 51/101 (50%), Gaps = 15/101 (14%) Query: 246 PGPPG---LPGGQGPPGS----------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292 PGPPG + G +GP G+ PGPKG PG PG PG G G +G G GP Sbjct: 1056 PGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRG 1115 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 S + G G GPPG PG G G RG PG G PGP G Sbjct: 1116 --SPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRG 1154 Score = 79.7 bits (195), Expect = 4e-15 Identities = 45/95 (47%), Positives = 51/95 (53%), Gaps = 7/95 (7%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-----PDLSHI--K 298 PGPPG G GP G+PGP G G GM G G PG G G GP+ P L I Sbjct: 67 PGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIPGH 126 Query: 299 QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP G PG G +GS+G+ G PG RG+ GP G Sbjct: 127 PGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGG 161 Score = 79.7 bits (195), Expect = 4e-15 Identities = 49/108 (45%), Positives = 55/108 (50%), Gaps = 22/108 (20%) Query: 245 LPGPPGLPGGQGPPG----SPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300 + G G PG GPPG PG KG PG PG PGPPG G RG +G G D QG Sbjct: 997 MQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGD-----QG 1051 Query: 301 RRGPVGPPGAPGRDGSKGERG----------APGPRG---SPGPPGSF 335 G GPPG G DG++G +G PGP+G SPG PG F Sbjct: 1052 EPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHF 1099 Score = 79.3 bits (194), Expect = 6e-15 Identities = 52/130 (40%), Positives = 58/130 (44%), Gaps = 36/130 (27%) Query: 235 GDKVLASNTYLPGPPG--------------LPGGQGPPGSPGPKGSPGFPGMP------- 273 G K + LPGPPG +PG GP G PG GSPGFPG+ Sbjct: 273 GIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVG 332 Query: 274 --------GPPGQPGPRGSMGPMG--PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAP 323 GP G PG RG GP G +P L +GP G PG PGR G G+ G P Sbjct: 333 DPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLP-----LKGPPGDPGFPGRYGETGDVGPP 387 Query: 324 GPRGSPGPPG 333 GP G G PG Sbjct: 388 GPPGLLGRPG 397 Score = 78.6 bits (192), Expect = 1e-14 Identities = 63/192 (32%), Positives = 71/192 (36%), Gaps = 59/192 (30%) Query: 247 GPPGLPG---GQGPPGSPG------------------PKGSPGFPGM------------- 272 GPPGLPG GPPG+ G P G PGFPG Sbjct: 536 GPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEK 595 Query: 273 --PGPPGQ-----PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGA--PGRDGSKGERGAP 323 PGPPG PG +G GP+GP G+ GPVGPPG PG G +G G P Sbjct: 596 GDPGPPGDHEDATPGGKGFPGPLGP--------PGKAGPVGPPGLGFPGPPGERGHPGVP 647 Query: 324 GPRGSPGPPGSFDFLLLMLADIRNDITELQEKVFGHRTHSSAEEFPLPQEFPSYPEAMDL 383 G G GP G L + D G + P P+ FP A L Sbjct: 648 GHPGVRGPDG--------LKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGL 699 Query: 384 GSGDDHPRRTET 395 D H R T Sbjct: 700 SGSDGHKGRPGT 711 Score = 78.6 bits (192), Expect = 1e-14 Identities = 42/100 (42%), Positives = 53/100 (53%), Gaps = 10/100 (10%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPD--LSHIK---- 298 +PGP G G GPPG GP+G PGFPG PG G+PG G G G + +S + Sbjct: 889 IPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRG 948 Query: 299 -QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 +G +G +GPPG G ++G PG PGPPG F Sbjct: 949 LRGAKGAIGPPGDEGEMAIISQKGTPG---EPGPPGDDGF 985 Score = 78.2 bits (191), Expect = 1e-14 Identities = 46/97 (47%), Positives = 51/97 (52%), Gaps = 9/97 (9%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRG-----SMGPMGPSPDLSHI-KQ 299 PG PGLPG G G GP G PG PG+ GPPGQPG G +G G D + +Q Sbjct: 192 PGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQ 251 Query: 300 GRRGP---VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP V PP G KG +G PG G PGPPG Sbjct: 252 GSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPG 288 Score = 78.2 bits (191), Expect = 1e-14 Identities = 41/89 (46%), Positives = 45/89 (50%), Gaps = 8/89 (8%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G G PG GPPG +G+PG PG PG PG PG G+ G G D+ GP G Sbjct: 813 GHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDV--------GPPG 864 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGSF 335 P G G G G GA GP G PG PG F Sbjct: 865 PAGMKGLPGLPGRPGAHGPPGLPGIPGPF 893 Score = 74.7 bits (182), Expect = 1e-13 Identities = 46/110 (41%), Positives = 53/110 (48%), Gaps = 21/110 (19%) Query: 245 LPGPPGLPGGQGPPGSPGPKGS------PGFPGM---PGPPGQPGPRGSMGPMGPSPDLS 295 L G G+ G +GPPG+ G KG PGFPG+ PG PG PGPRG G G + Sbjct: 87 LSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRG 146 Query: 296 HI----KQGRRGPVGPPGAPGRDGSKGE--------RGAPGPRGSPGPPG 333 +G GP GP G PG G KG +G G RG PG PG Sbjct: 147 DPGFPGGRGALGPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPG 196 Score = 73.2 bits (178), Expect = 4e-13 Identities = 44/101 (43%), Positives = 48/101 (47%), Gaps = 15/101 (14%) Query: 245 LPGPPGLPGGQGPPGSPG-----------PKGSPGFPGMPGPPGQPGPRGSMGPMGPSPD 293 L GP G PG +G PG PG P G PGFPG G G GP G G +G + Sbjct: 339 LIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGE 398 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPG-PRGSPGPPG 333 G GP GP G PG G GE G PG P +PG PG Sbjct: 399 AC---AGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPG 436 Score = 70.9 bits (172), Expect = 2e-12 Identities = 46/111 (41%), Positives = 54/111 (48%), Gaps = 20/111 (18%) Query: 235 GDKVLASNTYLPGPPGL---PGGQGPPGSP------GPK---GSPGFPGMPGPPGQPGPR 282 G + L+ + GP G PG +GP G P GPK G GFPG+PGPPG R Sbjct: 771 GKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCER 830 Query: 283 GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G+ G G + G G G PGAPG G G+ G PGP G G PG Sbjct: 831 GAPGIPG--------QPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPG 873 Score = 68.6 bits (166), Expect = 1e-11 Identities = 53/148 (35%), Positives = 57/148 (38%), Gaps = 9/148 (6%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 +PGPPG G G PG G KGS GPPG PG G G G D + G GP Sbjct: 717 IPGPPGFRGDMGDPGFGGEKGSSPV----GPPGPPGSPGVNGQKGIPGDPAF---GHLGP 769 Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQ--EKVFGHRTH 362 G G G G KG RG PG G+ GP G FL L R GH Sbjct: 770 PGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCE 829 Query: 363 SSAEEFPLPQEFPSYPEAMDLGSGDDHP 390 A P P YP + G P Sbjct: 830 RGAPGIPGQPGLPGYPGSPGAPGGKGQP 857 Score = 67.0 bits (162), Expect = 3e-11 Identities = 46/119 (38%), Positives = 51/119 (42%), Gaps = 37/119 (31%) Query: 247 GPPGLPGGQGPP---------------GSPGPKGSPGFPGMPGPPGQ------------- 278 G PG G QG P G G KG PG G+PGPPG+ Sbjct: 243 GDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKG 302 Query: 279 ----PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 PGPRG G G SP G +G +G G PG G G +G PG RG PGPPG Sbjct: 303 IPGFPGPRGDPGSYG-SPGF----PGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPG 356 Score = 62.0 bits (149), Expect = 9e-10 Identities = 49/135 (36%), Positives = 55/135 (40%), Gaps = 37/135 (27%) Query: 240 ASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-----PDL 294 A T PG PGL G G PG PG KG+PG G+ G G PG G G GP+ PD Sbjct: 207 AGPTGYPGEPGLVGPPGQPGRPGLKGNPGV-GVKGQMGDPGEVGQQGSPGPTLLVEPPDF 265 Query: 295 SHIK-----QGRRGPVGPPGAPGRDG-----------------------SKGERGAPGPR 326 K +G G VG PG PGR G S G G PG + Sbjct: 266 CLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLK 325 Query: 327 GS---PGPPGSFDFL 338 G G PG F + Sbjct: 326 GELGLVGDPGLFGLI 340 Score = 52.0 bits (123), Expect = 1e-06 Identities = 27/50 (54%), Positives = 27/50 (54%), Gaps = 3/50 (6%) Query: 246 PGPPGLPGGQGPPGSPGP---KGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292 PG G G G PGSPGP KG G G PG PG PGP G GP G P Sbjct: 1411 PGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGP 1460 Score = 46.2 bits (108), Expect = 5e-05 Identities = 25/53 (47%), Positives = 30/53 (56%), Gaps = 11/53 (20%) Query: 282 RGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 +GS GP GP G +GP+GP GAPG G GE+G RG GPPG+ Sbjct: 61 KGSRGPPGPP--------GPQGPIGPLGAPGPIGLSGEKGM---RGDRGPPGA 102 Score = 45.1 bits (105), Expect = 1e-04 Identities = 31/91 (34%), Positives = 34/91 (37%), Gaps = 34/91 (37%) Query: 245 LPGPPGLPGGQGP-----------PGSPGPKGSPGF------------PGMPGPPGQPGP 281 +PG PG PG +GP P PG KG PG PG PG G G Sbjct: 1378 IPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGE 1437 Query: 282 RGSMGPMGPSPDLSHIKQGRRGPVGPPGAPG 312 G G GP GP+G PG G Sbjct: 1438 DGYPGGPGPP-----------GPIGDPGPKG 1457 Score = 40.4 bits (93), Expect = 0.003 Identities = 21/45 (46%), Positives = 24/45 (53%), Gaps = 9/45 (20%) Query: 298 KQGRRGPVGPP---------GAPGRDGSKGERGAPGPRGSPGPPG 333 ++G RGP GPP GAPG G GE+G G RG PG G Sbjct: 60 EKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAG 104 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 99.0 bits (245), Expect = 7e-21 Identities = 54/113 (47%), Positives = 62/113 (54%), Gaps = 26/113 (23%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGF---PGMPGPPGQ------------PGPRGSMGPMG 289 +PG GLPG QGPPG PGPKG PG G PG PGQ PGP G +GP G Sbjct: 864 IPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQG 923 Query: 290 PSPDLSHIKQGRRGPVGPPGAP---------GRDGSKGERGAPGPRGSPGPPG 333 + ++ + G RGP GPPG P GR+G+KGE G PGP G GP G Sbjct: 924 KTGEVGPL--GERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAG 974 Score = 94.0 bits (232), Expect = 2e-19 Identities = 48/95 (50%), Positives = 54/95 (56%), Gaps = 14/95 (14%) Query: 246 PGPPGLPGGQGPPGS------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299 PGPPG PG GP G GP G+ G PG GPPG+ G +GS+GP G DL Sbjct: 1213 PGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDL----- 1267 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 GP G PG G DGS GE+G PG G PGPPG+ Sbjct: 1268 ---GPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGA 1299 Score = 92.0 bits (227), Expect = 8e-19 Identities = 46/90 (51%), Positives = 55/90 (61%), Gaps = 5/90 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSM---GPMGPSPDLSHIKQGRRG 303 G G G +GPPGS G KG G PG+PG PG+PGP+GS+ GP+GP + K G+ G Sbjct: 767 GQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKG--KSGKTG 824 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G G GS+GERG PG G PGP G Sbjct: 825 QPGLEGERGPPGSRGERGQPGATGQPGPKG 854 Score = 91.7 bits (226), Expect = 1e-18 Identities = 46/88 (52%), Positives = 52/88 (59%), Gaps = 4/88 (4%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305 G PG G +G PG GPKG GF G+PG PG+ G RG G +G P P + G RG Sbjct: 530 GRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPP---GEDGERGAE 586 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPG G+ G G RG GPRGSPGP G Sbjct: 587 GPPGPTGQAGEPGPRGLLGPRGSPGPTG 614 Score = 89.7 bits (221), Expect = 4e-18 Identities = 48/100 (48%), Positives = 54/100 (54%), Gaps = 14/100 (14%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGP G PG G G+PG KG+ G PG PGPPGQ G GS G GP + G +GP Sbjct: 610 PGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIG--TPGEKGPP 667 Query: 306 GPPGA------------PGRDGSKGERGAPGPRGSPGPPG 333 G PG PG +G GE+GA GP GS GPPG Sbjct: 668 GNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPG 707 Score = 86.7 bits (213), Expect = 4e-17 Identities = 49/102 (48%), Positives = 53/102 (51%), Gaps = 14/102 (13%) Query: 235 GDKVLASNTYLPG---PPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS 291 G K T LPG PPG PG G GSPG KG PG G PGPPG G G+ GP Sbjct: 1253 GAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGP---- 1308 Query: 292 PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G+RGP G G GR+G KG +G PGP G PG G Sbjct: 1309 -------PGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTG 1343 Score = 85.1 bits (209), Expect = 1e-16 Identities = 45/89 (50%), Positives = 50/89 (56%), Gaps = 4/89 (4%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRGPV 305 G GL G GPPG G KG G PG+ GP PGP+G GP GP L H G GP+ Sbjct: 1403 GHIGLIGLIGPPGEAGEKGDQGLPGVQGP---PGPKGDPGPPGPIGSLGHPGPPGVAGPL 1459 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G G+ G GS G RG GP G PGPPG+ Sbjct: 1460 GQKGSKGSPGSMGPRGDTGPAGPPGPPGA 1488 Score = 84.7 bits (208), Expect = 1e-16 Identities = 49/113 (43%), Positives = 55/113 (48%), Gaps = 25/113 (22%) Query: 246 PGPPGLPGGQG---PPGSPGPKGS------------PGFPGMPGPPGQPGPRGSMGPMGP 290 PGPPG G QG PPG G KG PG G+PGPPG+ G G +G MGP Sbjct: 1111 PGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGP 1170 Query: 291 ----------SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P S G G VG PGA G G +G+ G PGP G+PG PG Sbjct: 1171 HGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPG 1223 Score = 83.6 bits (205), Expect = 3e-16 Identities = 50/122 (40%), Positives = 55/122 (45%), Gaps = 34/122 (27%) Query: 246 PGPPGLPGGQ------------------GPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGP 287 PGPPG PG Q GP G GP G GFPG G PG PGP G G Sbjct: 937 PGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGD 996 Query: 288 MG-PSPDLSHIKQGRRGPVGPPGA---------------PGRDGSKGERGAPGPRGSPGP 331 G P P ++ G RGP+GP G G+ GS+GERG PGP G G Sbjct: 997 KGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGI 1056 Query: 332 PG 333 PG Sbjct: 1057 PG 1058 Score = 82.8 bits (203), Expect = 5e-16 Identities = 47/100 (47%), Positives = 52/100 (52%), Gaps = 17/100 (17%) Query: 246 PGPPGLPGGQGPPGSP------GPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299 PG PGLPG GP G P G KG+ G PG GPPG PGPRG G G + Q Sbjct: 670 PGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSG-----NRGLQ 724 Query: 300 GRRGPVGPPGAP------GRDGSKGERGAPGPRGSPGPPG 333 G +G G G P G G +G+ GAPGPRG GP G Sbjct: 725 GEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEG 764 Score = 82.4 bits (202), Expect = 7e-16 Identities = 51/138 (36%), Positives = 66/138 (47%), Gaps = 22/138 (15%) Query: 218 KIALLPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGS------PGPKGSPGFPG 271 ++ + AD + + GD + G PGLPG +G G PGP G G G Sbjct: 525 RVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERG 584 Query: 272 MPGPP------GQPGPRGSMGPMG-PSP---------DLSHIKQGRRGPVGPPGAPGRDG 315 GPP G+PGPRG +GP G P P D + +G GP G PG PG+ G Sbjct: 585 AEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQG 644 Query: 316 SKGERGAPGPRGSPGPPG 333 + G +G PGP+G G PG Sbjct: 645 NHGSQGLPGPQGLIGTPG 662 Score = 81.6 bits (200), Expect = 1e-15 Identities = 48/112 (42%), Positives = 57/112 (50%), Gaps = 26/112 (23%) Query: 246 PGPPGLPG------GQGPPGSPGPKGSPGF------PGMPGPPGQPGPRGSMGP------ 287 PGP G PG +GPPG GP+G G PG+ G PGQ GP G +GP Sbjct: 1333 PGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGL 1392 Query: 288 ---MGPSPDLSHIKQGRRGPVGPPGAPGRDGSK---GERGAPGPRGSPGPPG 333 GP + HI G G +GPPG G G + G +G PGP+G PGPPG Sbjct: 1393 KGDTGPKGEKGHI--GLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPG 1442 Score = 81.3 bits (199), Expect = 1e-15 Identities = 49/118 (41%), Positives = 53/118 (44%), Gaps = 31/118 (26%) Query: 247 GPPGLPGGQGPPGS------------PGPK------------GSPGFPGMPGPPGQPGPR 282 G PGL G +GPPGS PGPK G G PG+ GPPG PGP+ Sbjct: 824 GQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPK 883 Query: 283 GSMGPMGPSPDLSHIK-------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G G H QG+ GP GP G G G GE G G RG PGPPG Sbjct: 884 GPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPG 941 Score = 81.3 bits (199), Expect = 1e-15 Identities = 43/95 (45%), Positives = 52/95 (54%), Gaps = 7/95 (7%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRGPV 305 G PG G +GP G G KGS G G PGP G+ G G +GP+GP ++G +G V Sbjct: 1022 GLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDV 1081 Query: 306 GPPGAPGRDGSKGERGAP------GPRGSPGPPGS 334 G PG G G KG+ G P GP G PGPPG+ Sbjct: 1082 GAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGA 1116 Score = 80.9 bits (198), Expect = 2e-15 Identities = 50/105 (47%), Positives = 52/105 (49%), Gaps = 8/105 (7%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289 I G N PG PG PG QG GS PGP+G G PG GPPG PG G G G Sbjct: 621 IDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDG 680 Query: 290 PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 P L H G GP G GA G GS G G PGPRG G G+ Sbjct: 681 P---LGH--PGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGN 720 Score = 80.9 bits (198), Expect = 2e-15 Identities = 49/122 (40%), Positives = 55/122 (45%), Gaps = 23/122 (18%) Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPG---------PKGSPGFPGMPGP--------- 275 TG+K GPPG PG +G G+ G KG GFPG G Sbjct: 691 TGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGK 750 Query: 276 PGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSF 335 PG PGPRG GP GP + G+ G GPPG+ G G G G PG G PGP GS Sbjct: 751 PGAPGPRGEDGPEGPKG-----QAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSI 805 Query: 336 DF 337 F Sbjct: 806 GF 807 Score = 80.1 bits (196), Expect = 3e-15 Identities = 52/118 (44%), Positives = 56/118 (47%), Gaps = 32/118 (27%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP-- 304 GP G G +G G+PG KGS G G GPPGQPG RG G P P + QGRRGP Sbjct: 1070 GPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAG--HPGPPGADGAQGRRGPPG 1127 Query: 305 ----------------VGPP---GAPGRDGSKGE---------RGAPGPRGSPGPPGS 334 +GPP G PG G KGE GAPGPRG GP GS Sbjct: 1128 LFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGS 1185 Score = 80.1 bits (196), Expect = 3e-15 Identities = 45/101 (44%), Positives = 50/101 (49%), Gaps = 20/101 (19%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSP------------GFPGMPGPPGQPGPRGSMGPMGPSP 292 LPGPPG G G GS GP G+P G PG+PG GQPG G G G + Sbjct: 1152 LPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDA- 1210 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP G PG PG G GE+G GP G+ GPPG Sbjct: 1211 -------GDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPG 1244 Score = 79.3 bits (194), Expect = 6e-15 Identities = 47/105 (44%), Positives = 51/105 (48%), Gaps = 16/105 (15%) Query: 245 LPGPPGLPGG------QGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI- 297 LPG PGL G QGP G GP G PG G G PG G RG G GP D Sbjct: 495 LPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDG 554 Query: 298 ------KQGRRGP---VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 ++G+RG VG PG PG DG +G G PGP G G PG Sbjct: 555 LPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPG 599 Score = 78.6 bits (192), Expect = 1e-14 Identities = 47/111 (42%), Positives = 55/111 (49%), Gaps = 14/111 (12%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG---------PRGSM 285 G+ T PGP G+ G QG G GP G G PG PGPPG+ G +G + Sbjct: 902 GELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGEL 961 Query: 286 GPMGPSPDLSHIKQGRRGPVGP---PGAPGRDGSKGERGAPGPRGSPGPPG 333 GP GP G RG GP PG PG G KG++G PGP G+ G PG Sbjct: 962 GPPGPLGKEG--PAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPG 1010 Score = 78.6 bits (192), Expect = 1e-14 Identities = 41/89 (46%), Positives = 47/89 (52%), Gaps = 1/89 (1%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRGP 304 PG PG PG +GP G G +G G G G PG GP G GPMG + +G RG Sbjct: 1303 PGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGI 1362 Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G PG G+ G+ G PGP G G PG Sbjct: 1363 PGPVGEPGLLGAPGQMGPPGPLGPSGLPG 1391 Score = 77.8 bits (190), Expect = 2e-14 Identities = 46/107 (42%), Positives = 51/107 (47%), Gaps = 23/107 (21%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPG------------FPGMPG------PPGQPGPRGSMGP 287 PGP GL G +GPPG G GSPG PG G P G+ G RG GP Sbjct: 988 PGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGP 1047 Query: 288 MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 GP+ K G GP+GP G PG G GE G G G+PG GS Sbjct: 1048 PGPTG-----KDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGS 1089 Score = 77.4 bits (189), Expect = 2e-14 Identities = 51/139 (36%), Positives = 55/139 (39%), Gaps = 43/139 (30%) Query: 238 VLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSMGPMG-- 289 V+ GPPG PG QG G GP G PGFPG PGPPG PG G GP G Sbjct: 383 VIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTV 442 Query: 290 ------------PSPDLSHIK-----------------------QGRRGPVGPPGAPGRD 314 P +S + GR GPVG PG PG Sbjct: 443 IMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLK 502 Query: 315 GSKGERGAPGPRGSPGPPG 333 G +G G GPRG GP G Sbjct: 503 GEEGAEGPQGPRGLQGPHG 521 Score = 77.0 bits (188), Expect = 3e-14 Identities = 43/93 (46%), Positives = 47/93 (50%), Gaps = 4/93 (4%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI----KQG 300 LPG PG PG +G G PGP G G G G GQPG G GP G + + G Sbjct: 792 LPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPG 851 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G VG GAPG G KG G GP G PGP G Sbjct: 852 PKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKG 884 Score = 77.0 bits (188), Expect = 3e-14 Identities = 41/92 (44%), Positives = 47/92 (51%), Gaps = 5/92 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G PG G GPPG+ GP G G G G PG G +G G GP + G RGP G Sbjct: 1055 GIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPG-----QPGIRGPAG 1109 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGSFDFL 338 PG PG DG++G RG PG G G G F+ Sbjct: 1110 HPGPPGADGAQGRRGPPGLFGQKGDDGVRGFV 1141 Score = 75.5 bits (184), Expect = 8e-14 Identities = 42/98 (42%), Positives = 49/98 (50%), Gaps = 10/98 (10%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG-------PMGPSPDLSHIKQ 299 G PG PG +G G GPKG G G GPPG G +G +G P P P S Sbjct: 749 GKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFP 808 Query: 300 GRRGPVGPPGAPGRDGS---KGERGAPGPRGSPGPPGS 334 G GP+G G G+ G +GERG PG RG G PG+ Sbjct: 809 GPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGA 846 Score = 75.5 bits (184), Expect = 8e-14 Identities = 41/88 (46%), Positives = 45/88 (51%), Gaps = 1/88 (1%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP-SPDLSHIKQGRRGPV 305 G GLPG G G GP G G G GPPG G G GP+GP P + G G Sbjct: 1019 GGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDK 1078 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GAPG GSKG++G GP G PG G Sbjct: 1079 GDVGAPGHKGSKGDKGDAGPPGQPGIRG 1106 Score = 73.6 bits (179), Expect = 3e-13 Identities = 43/107 (40%), Positives = 52/107 (48%), Gaps = 5/107 (4%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GPPG G GPPG G G PG PG+ GP GQ G +GS G MGP D G GP G Sbjct: 1430 GPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGD-----TGPAGPPG 1484 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQ 353 PPGAP R P P G + +L L + ++ +L+ Sbjct: 1485 PPGAPAELHGLRRRRRFVPVPLPVVEGGLEEVLASLTSLSLELEQLR 1531 Score = 73.2 bits (178), Expect = 4e-13 Identities = 45/98 (45%), Positives = 48/98 (48%), Gaps = 10/98 (10%) Query: 246 PGPPGLPGGQGP---PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----PSPDLSHIK 298 PGP GL G GP PG PG KG G G GP G GP G G +G P D + Sbjct: 481 PGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGL 540 Query: 299 QGRRGPVGP---PGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP G G PG G KG+RG G G PGPPG Sbjct: 541 PGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPG 578 Score = 72.0 bits (175), Expect = 9e-13 Identities = 42/104 (40%), Positives = 51/104 (49%), Gaps = 1/104 (0%) Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG- 289 K +G++ L G G PG +G G G +G PG PG G G GP+G G G Sbjct: 715 KGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGE 774 Query: 290 PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P S ++G+ G G PG PGR G KG G PGP G G G Sbjct: 775 EGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKG 818 Score = 69.7 bits (169), Expect = 4e-12 Identities = 37/83 (44%), Positives = 43/83 (51%), Gaps = 8/83 (9%) Query: 255 QGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRD 314 +GPPG G G PG G+PG PG G G+ GP GP +G +GP GPPG G+ Sbjct: 478 KGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGP--------RGLQGPHGPPGRVGKM 529 Query: 315 GSKGERGAPGPRGSPGPPGSFDF 337 G G GA G G GP G F Sbjct: 530 GRPGADGARGLPGDTGPKGDRGF 552 Score = 66.6 bits (161), Expect = 4e-11 Identities = 38/92 (41%), Positives = 43/92 (46%), Gaps = 1/92 (1%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRG 303 + GPPG G G PG G G PG G G G GPRG GP GP + + + G G Sbjct: 477 MKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADG 536 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPGSF 335 G PG G G +G G PG G G G F Sbjct: 537 ARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDF 568 Score = 60.1 bits (144), Expect = 4e-09 Identities = 36/84 (42%), Positives = 42/84 (50%), Gaps = 19/84 (22%) Query: 258 PGSPGPKGSPGFPGM-------PGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGA 310 PG+ G KG+ G P + GPPG PGP+G +GP GP GP G PG Sbjct: 370 PGA-GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPP-----------GPPGFPGD 417 Query: 311 PGRDGSKGERGAPGPRGSPGPPGS 334 PG G G G PG G GPPG+ Sbjct: 418 PGPPGPAGLPGIPGIDGIRGPPGT 441 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 98.6 bits (244), Expect = 9e-21 Identities = 46/88 (52%), Positives = 50/88 (56%), Gaps = 11/88 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGP G PG GPPG+ G GSPG PG GPPG+PG G GP GP G + Sbjct: 173 PGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPP-----------GAI 221 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G G+DG G G PG RG PGPPG Sbjct: 222 GPSGPAGKDGESGRPGRPGERGLPGPPG 249 Score = 95.5 bits (236), Expect = 8e-20 Identities = 46/88 (52%), Positives = 50/88 (56%), Gaps = 5/88 (5%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG GLPG G PG G +G G PG PG PG PGP G +GP G S D +G GP Sbjct: 1016 PGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGD-----RGESGPA 1070 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP GAPG GS+G G GPRG G G Sbjct: 1071 GPAGAPGPAGSRGAPGPQGPRGDKGETG 1098 Score = 94.7 bits (234), Expect = 1e-19 Identities = 46/88 (52%), Positives = 50/88 (56%), Gaps = 1/88 (1%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305 G PG PGG G G PGP GS G G PGPPG GPRG G MG P P + G+ G Sbjct: 537 GMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGER 596 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG PG G G+ G GP+G PGP G Sbjct: 597 GGPGGPGPQGPPGKNGETGPQGPPGPTG 624 Score = 94.0 bits (232), Expect = 2e-19 Identities = 55/113 (48%), Positives = 62/113 (54%), Gaps = 22/113 (19%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSMG-PMGPSPDLSHIKQ 299 GPPG GG+G G PGP G+ G PG+ G PG+ PGP+G G P GP D K Sbjct: 699 GPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKD 758 Query: 300 GRR---GPVGPPGAPGRDGSKGERGAP------GPRGSP------GPPGSFDF 337 G R GP+GPPG G+ G KGE GAP GPRGSP GPPG F Sbjct: 759 GPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGF 811 Score = 93.2 bits (230), Expect = 4e-19 Identities = 48/95 (50%), Positives = 54/95 (56%), Gaps = 7/95 (7%) Query: 246 PGPPGLPGGQGPPGSP------GPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIK 298 PGPPG PG G PGSP GP GSPG G PG G+PGP+G G G P P + Sbjct: 332 PGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGS 391 Query: 299 QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G +G +GP G PG G G RG PGP G+ G PG Sbjct: 392 PGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPG 426 Score = 93.2 bits (230), Expect = 4e-19 Identities = 49/98 (50%), Positives = 54/98 (55%), Gaps = 11/98 (11%) Query: 246 PGPPGLPGGQG---PPGSPGPKGSPGFPGMPGP------PGQPGPRGSMGPMGPSPDLSH 296 PGPPG G G PPG GP+G PG G PGP PG+ G RG GP GP P Sbjct: 551 PGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERG--GPGGPGPQGPP 608 Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 K G GP GPPG G G KG+ G PGP+G G PG+ Sbjct: 609 GKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGT 646 Score = 92.4 bits (228), Expect = 6e-19 Identities = 45/88 (51%), Positives = 50/88 (56%), Gaps = 8/88 (9%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG G G PGSPG +G PG PG GP G PGP G++GP GP+ G+ G Sbjct: 182 PGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPA--------GKDGES 233 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG PG G G G GP G PG PG Sbjct: 234 GRPGRPGERGLPGPPGIKGPAGIPGFPG 261 Score = 92.4 bits (228), Expect = 6e-19 Identities = 55/119 (46%), Positives = 65/119 (54%), Gaps = 31/119 (26%) Query: 246 PGPPGLPGGQGPPGSPGPKGS---PGFPGMPGPPGQPGPRGSMGPMGP------------ 290 PG G+PG +G GSPGPKG PG PG G PG+ GPRG GP+GP Sbjct: 722 PGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGE 781 Query: 291 --SPDLSHI--------KQGRRGPVGP---PGAPGRD---GSKGERGAPGPRGSPGPPG 333 +P L I ++G GP GP PGAPG++ G KGERGAPG +G GPPG Sbjct: 782 GGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPG 840 Score = 92.4 bits (228), Expect = 6e-19 Identities = 48/95 (50%), Positives = 54/95 (56%), Gaps = 7/95 (7%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPG---MPGPPGQPGPRGSMGPMGPSPDL----SHIK 298 PG G PG QGPPG+PGP G G G + GPPG PGPRGS GP G + ++ Sbjct: 929 PGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGL 988 Query: 299 QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G RGP GP G PG G+ GE G G GS G PG Sbjct: 989 SGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPG 1023 Score = 92.4 bits (228), Expect = 6e-19 Identities = 44/88 (50%), Positives = 51/88 (57%), Gaps = 1/88 (1%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-PDLSHIKQGRRGPV 305 G G+ G +G PG+PG GSPG G G G PGP G GP+GPS P G GP+ Sbjct: 1101 GAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPI 1160 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPG G G +G G+PG G PGPPG Sbjct: 1161 GPPGPRGNRGERGSEGSPGHPGQPGPPG 1188 Score = 92.0 bits (227), Expect = 8e-19 Identities = 50/110 (45%), Positives = 59/110 (53%), Gaps = 10/110 (9%) Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--S 291 TG L LPG G PG GP G+PG +G PG PG G G G RGS G GP Sbjct: 278 TGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGP 337 Query: 292 PDLSHI--KQGRRGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPG 333 P + G +G VGP G+PG +G+ G+RG PGP +G PGPPG Sbjct: 338 PGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPG 387 Score = 90.9 bits (224), Expect = 2e-18 Identities = 50/97 (51%), Positives = 52/97 (53%), Gaps = 10/97 (10%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRGPV 305 G PG PG G PG PGP GSPG G PGP G G GS G GP D ++G G Sbjct: 879 GLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQ 938 Query: 306 GPPGAPGRDGSKGERGA---------PGPRGSPGPPG 333 GPPGAPG G G GA PGPRGSPGP G Sbjct: 939 GPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQG 975 Score = 90.5 bits (223), Expect = 2e-18 Identities = 47/91 (51%), Positives = 53/91 (58%), Gaps = 5/91 (5%) Query: 246 PGP---PGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 PGP PG PG G PG G +G+PG G GPPG GP G GP GP P +K G R Sbjct: 806 PGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGP-PGPQGVK-GER 863 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G PGA G G++G G PG G+PGPPG Sbjct: 864 GSPGGPGAAGFPGARGLPGPPGSNGNPGPPG 894 Score = 89.7 bits (221), Expect = 4e-18 Identities = 48/102 (47%), Positives = 51/102 (50%), Gaps = 15/102 (14%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRG-----SMGPMGPSP--DLSHIKQ 299 GP G G GPPG PG G PG PG PG PG PGP G GP SP D +K Sbjct: 103 GPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKS 162 Query: 300 --------GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP GPPG PG G+ G G+PG G GPPG Sbjct: 163 GVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPG 204 Score = 89.7 bits (221), Expect = 4e-18 Identities = 45/89 (50%), Positives = 50/89 (56%), Gaps = 1/89 (1%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-PDLSHIKQGRRGP 304 PG G+PGG G G PG G PG G PGPPG G G GP GPS P G GP Sbjct: 524 PGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGP 583 Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GAPG++G +G G PGP+G PG G Sbjct: 584 KGNDGAPGKNGERGGPGGPGPQGPPGKNG 612 Score = 89.7 bits (221), Expect = 4e-18 Identities = 49/94 (52%), Positives = 56/94 (59%), Gaps = 8/94 (8%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP-- 304 GPPG G +G GSPG G+ GFPG G PG PG G+ GP GPS S K G GP Sbjct: 852 GPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSG--SPGKDGPPGPAG 909 Query: 305 -VGPPGAPGRDGSKGERGAPGPRGSP---GPPGS 334 G PG+PG G KG+ G PG +GSP GPPG+ Sbjct: 910 NTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGA 943 Score = 87.0 bits (214), Expect = 3e-17 Identities = 46/96 (47%), Positives = 54/96 (56%), Gaps = 7/96 (7%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGF------PGMPGPPGQPGPRGSMGPMG-PSPDLSHI 297 +PG PGL G +GPPG G G+PG PG G G+PGPRG G G P + Sbjct: 403 IPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKG 462 Query: 298 KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 + G+ G G PGA G G+ GERGAPG RG GP G Sbjct: 463 EDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNG 498 Score = 86.7 bits (213), Expect = 4e-17 Identities = 48/105 (45%), Positives = 54/105 (51%), Gaps = 17/105 (16%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGF------------PGMPGPPGQPGPRGSMGPMGPSP 292 LPGPPG+ G G PG PG KG GF PG+ G G PG G+ GPMGP Sbjct: 244 LPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRG 303 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 G RG G PGA G G+ G RG+ G G PGPPG+ F Sbjct: 304 -----APGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGF 343 Score = 86.7 bits (213), Expect = 4e-17 Identities = 48/104 (46%), Positives = 52/104 (50%), Gaps = 23/104 (22%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMP------------GPP---GQPGPRGSMGPMG 289 LPG G PG G PG PGPKG G PG P GPP G PG RG GP G Sbjct: 643 LPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPG 702 Query: 290 PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P +G +G GPPG PG G+ G +G PG RG G PG Sbjct: 703 P--------EGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPG 738 Score = 86.3 bits (212), Expect = 5e-17 Identities = 46/101 (45%), Positives = 49/101 (48%), Gaps = 8/101 (7%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292 I G+K A PGP G G G PG G G PG GMPG PG PG G GP G Sbjct: 499 IPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPG--- 555 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 QG G GPPG G G G G PGP+G+ G PG Sbjct: 556 -----SQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPG 591 Score = 84.7 bits (208), Expect = 1e-16 Identities = 43/89 (48%), Positives = 47/89 (52%), Gaps = 1/89 (1%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305 G PG PG G PG+ G +G+PGF G GP G PG +G G G P P G G Sbjct: 468 GSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRD 527 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G PG PG G G G PG G PGPPGS Sbjct: 528 GVPGGPGMRGMPGSPGGPGSDGKPGPPGS 556 Score = 83.6 bits (205), Expect = 3e-16 Identities = 41/88 (46%), Positives = 44/88 (50%), Gaps = 2/88 (2%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG G PG +G G+PG G G PG PGP G PG G GP GP G +G Sbjct: 575 PGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTG--PGGDKGDT 632 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPG G G G G PG G PG PG Sbjct: 633 GPPGPQGLQGLPGTGGPPGENGKPGEPG 660 Score = 83.6 bits (205), Expect = 3e-16 Identities = 47/110 (42%), Positives = 52/110 (47%), Gaps = 19/110 (17%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ------- 299 GP G PG G PG G G+PG PG+ GP G PG RG GP GP+ Q Sbjct: 765 GPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGK 824 Query: 300 ------GRRGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPGSFDF 337 G +G GPPG G G G G PGP RGSPG PG+ F Sbjct: 825 GERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGF 874 Score = 83.2 bits (204), Expect = 4e-16 Identities = 46/91 (50%), Positives = 52/91 (57%), Gaps = 4/91 (4%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRG 303 L GPPG+PG P GSPGP+G G G PG G G RG GP G P + + GR G Sbjct: 958 LAGPPGMPG---PRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDG 1014 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G G PGRDGS G +G G GSPG PG+ Sbjct: 1015 NPGSDGLPGRDGSPGGKGDRGENGSPGAPGA 1045 Score = 82.4 bits (202), Expect = 7e-16 Identities = 46/104 (44%), Positives = 51/104 (49%), Gaps = 16/104 (15%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGF---PGMPGPPGQPGPRGSMGPMGP------------- 290 G PG G +G PG PGP+G PG G GPPG GP G G GP Sbjct: 588 GAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTG 647 Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 P + K G GP G GAPG G KG+ GAPG RG PG G+ Sbjct: 648 GPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGA 691 Score = 82.0 bits (201), Expect = 9e-16 Identities = 45/90 (50%), Positives = 50/90 (55%), Gaps = 8/90 (8%) Query: 247 GPPGLPGGQGPPGSP---GPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303 GPPG G G PGSP GPKG G PG G PG GP G+ GP+G ++ I G RG Sbjct: 903 GPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLG----IAGI-TGARG 957 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPG PG GS G +G G G PG G Sbjct: 958 LAGPPGMPGPRGSPGPQGVKGESGKPGANG 987 Score = 81.3 bits (199), Expect = 1e-15 Identities = 45/91 (49%), Positives = 46/91 (50%), Gaps = 11/91 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGF---PGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 PG PG PG GPPG GP G G G GP G PGP GS G GP QG R Sbjct: 1040 PGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGP--------QGPR 1091 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G G G G KG RG PG G+PG PG Sbjct: 1092 GDKGETGERGAAGIKGHRGFPGNPGAPGSPG 1122 Score = 81.3 bits (199), Expect = 1e-15 Identities = 45/101 (44%), Positives = 49/101 (48%), Gaps = 11/101 (10%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292 I G + N PG PG G QG GSPGP G G G GPPG+ G G GP+GP Sbjct: 1105 IKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPP- 1163 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G G G +GS G G PGP G PG PG Sbjct: 1164 ----------GPRGNRGERGSEGSPGHPGQPGPPGPPGAPG 1194 Score = 80.9 bits (198), Expect = 2e-15 Identities = 47/111 (42%), Positives = 55/111 (49%), Gaps = 22/111 (19%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGP---PGQPGPRGSMGPMGPS----------- 291 PGP G G QGPPG PG GSPG G GP PG PG G+ GP GP+ Sbjct: 371 PGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGG 430 Query: 292 ---PDLSHIK-----QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 P + K +G RG G PG PG G G+ G+PG G+ G PG+ Sbjct: 431 AGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGA 481 Score = 80.9 bits (198), Expect = 2e-15 Identities = 42/88 (47%), Positives = 46/88 (52%), Gaps = 5/88 (5%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGP G G +G G PGP+G G PG GPPG+ G G GP G + G G Sbjct: 620 PGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAG-----APGAPGGK 674 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GAPG G G GAPG RG GPPG Sbjct: 675 GDAGAPGERGPPGLAGAPGLRGGAGPPG 702 Score = 79.0 bits (193), Expect = 7e-15 Identities = 43/97 (44%), Positives = 48/97 (49%), Gaps = 14/97 (14%) Query: 246 PGPPGLPGGQGP---------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296 PGPPG G GP PG PG +G PG PG+ GP G PG G G G Sbjct: 215 PGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDG---- 270 Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 + G +G G PG G +G GE GAPGP G G PG Sbjct: 271 -RNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPG 306 Score = 52.4 bits (124), Expect = 7e-07 Identities = 32/77 (41%), Positives = 33/77 (42%), Gaps = 10/77 (12%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G G PG GPPG G +G G G PG PGQPGP G G GP G VG Sbjct: 1152 GTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPC----------CGGVG 1201 Query: 307 PPGAPGRDGSKGERGAP 323 G G K AP Sbjct: 1202 AAAIAGIGGEKAGGFAP 1218 Score = 44.7 bits (104), Expect = 2e-04 Identities = 26/65 (40%), Positives = 31/65 (47%), Gaps = 7/65 (10%) Query: 276 PGQPGPRGSMGPMGPSPDLSHIKQGR-RGPVGP------PGAPGRDGSKGERGAPGPRGS 328 P P G + P P + + +GP GP PG PGR+G G G PG GS Sbjct: 75 PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGS 134 Query: 329 PGPPG 333 PGPPG Sbjct: 135 PGPPG 139 Score = 35.4 bits (80), Expect = 0.093 Identities = 17/34 (50%), Positives = 20/34 (58%), Gaps = 1/34 (2%) Query: 246 PGPPGLPGGQGPPGSPGP-KGSPGFPGMPGPPGQ 278 PG PG PG GPPG+PGP G G + G G+ Sbjct: 1178 PGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGE 1211 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 97.4 bits (241), Expect = 2e-20 Identities = 51/106 (48%), Positives = 59/106 (55%), Gaps = 20/106 (18%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQPGPR---------------GSMGP 287 PG G PG +GPPG GPKG+PG FPG PGPPG+PGP G GP Sbjct: 1299 PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP 1358 Query: 288 MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPS + G G GPPGA G +G +GE+GA G G+ GPPG Sbjct: 1359 PGPSGEAG--PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPG 1402 Score = 94.4 bits (233), Expect = 2e-19 Identities = 54/115 (46%), Positives = 58/115 (50%), Gaps = 28/115 (24%) Query: 247 GPPGLPGGQGPPGSPGPKGSP------------GFPGMPGPPGQPGPR------GSMGPM 288 G PGL GG+GP G PGP GSP G PG PGP G PGP G GP Sbjct: 1051 GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ 1110 Query: 289 GPS-PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS---------PGPPG 333 GP+ D G GP GP G+PG DG KGE G PG +GS PGPPG Sbjct: 1111 GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1165 Score = 94.4 bits (233), Expect = 2e-19 Identities = 47/88 (53%), Positives = 50/88 (56%), Gaps = 11/88 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG G QG PG PG KG G G GPPG PGPRG GP G GP Sbjct: 1203 PGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGP-----------NGADGPQ 1251 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPG+ G G GE+G PG G+PGPPG Sbjct: 1252 GPPGSVGSVGGVGEKGEPGEAGNPGPPG 1279 Score = 92.0 bits (227), Expect = 8e-19 Identities = 50/98 (51%), Positives = 56/98 (57%), Gaps = 10/98 (10%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGP-SPDLSHIKQGR 301 PG PG PG G G PGPKG+ G G PGPPGQ PGP+G GP GP P QG+ Sbjct: 672 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 731 Query: 302 RGPV------GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GPPG PG++G GE+GA GP G GP G Sbjct: 732 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIG 769 Score = 92.0 bits (227), Expect = 8e-19 Identities = 51/111 (45%), Positives = 58/111 (52%), Gaps = 29/111 (26%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------------------------PGPR 282 GPPGLPG +G PGS G KG PG G+ GPPG+ PGP Sbjct: 1447 GPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1506 Query: 283 GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G +GP GP P L G +GP G G+ G G KG+ G PGP GSPGPPG Sbjct: 1507 GPLGPPGP-PGL----PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1552 Score = 90.9 bits (224), Expect = 2e-18 Identities = 44/88 (50%), Positives = 52/88 (59%), Gaps = 10/88 (11%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305 GP G G +GP G PGPKG+ G G PGPPG+ GP+G GP+G P P +GP Sbjct: 898 GPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP---------KGPP 948 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPG G G G+RG G +G GPPG Sbjct: 949 GPPGKDGLPGHPGQRGETGFQGKTGPPG 976 Score = 90.9 bits (224), Expect = 2e-18 Identities = 49/105 (46%), Positives = 53/105 (50%), Gaps = 8/105 (7%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSP------GPKGSPGFPGMPGPPGQPGPRGSMGPM 288 G + T PGP G GG GPPG P GP+G GFPG GPPG PG G G Sbjct: 901 GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHP 960 Query: 289 GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G + QG+ GP GP G G G GE G G RG PGPPG Sbjct: 961 GQRGETGF--QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 1003 Score = 90.9 bits (224), Expect = 2e-18 Identities = 51/106 (48%), Positives = 56/106 (52%), Gaps = 20/106 (18%) Query: 246 PGPPGLPGGQGPPGS---PGPKGSPGFP---GMPGPPGQ------------PGPRGSMGP 287 PGPPG G QGP G PGPKG PG P G+PG PGQ PGP G +GP Sbjct: 924 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 983 Query: 288 MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP+ + I G RG GPPG PG G G G G +G PGP G Sbjct: 984 QGPTGETGPI--GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG 1027 Score = 90.1 bits (222), Expect = 3e-18 Identities = 52/119 (43%), Positives = 59/119 (49%), Gaps = 19/119 (15%) Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP---------PGQPGPRGS 284 TGD + G G+PG G PG GPKGS GFPG PG G+PGPRG Sbjct: 834 TGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQ 893 Query: 285 MGPMGP-------SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGA---PGPRGSPGPPG 333 GP GP P +G G GPPG PG G +G +G PGP+G PGPPG Sbjct: 894 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG 952 Score = 89.4 bits (220), Expect = 5e-18 Identities = 51/135 (37%), Positives = 60/135 (44%), Gaps = 31/135 (22%) Query: 230 GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSM---- 285 G + G A + GPPGL G GPPG PG +G PG PG+PG G PGP G+M Sbjct: 449 GMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 508 Query: 286 ------GPMGPSPDLSHIK---------------------QGRRGPVGPPGAPGRDGSKG 318 G GP+ + GR GPVG PG+ G G G Sbjct: 509 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 568 Query: 319 ERGAPGPRGSPGPPG 333 + G GPRG GPPG Sbjct: 569 DPGPQGPRGVQGPPG 583 Score = 89.4 bits (220), Expect = 5e-18 Identities = 45/88 (51%), Positives = 50/88 (56%), Gaps = 4/88 (4%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305 G PG GG+G PG PG KG GF G+PG PG G RG GP G P P +G G + Sbjct: 592 GRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEI 651 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G P G G RG GPRG+PG PG Sbjct: 652 GPRGLP---GEAGPRGLLGPRGTPGAPG 676 Score = 88.6 bits (218), Expect = 9e-18 Identities = 47/97 (48%), Positives = 53/97 (54%), Gaps = 10/97 (10%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMP---GPPGQPGPRGSMGPMG-PSPDLSHIK---- 298 GP GLPG GP G GP+G+PG PG P G G PGP+G+MGP G P P Sbjct: 652 GPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ 711 Query: 299 --QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G +GP+GPPG G G G G PG G PG PG Sbjct: 712 GLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPG 748 Score = 88.6 bits (218), Expect = 9e-18 Identities = 45/102 (44%), Positives = 54/102 (52%), Gaps = 8/102 (7%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292 + GDK + PGPPG G GPPG PG +G PG G G G+ G +G G GP Sbjct: 1343 VGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP-- 1400 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G+ GPVGP G G+ G +G RG PGP G G PG+ Sbjct: 1401 ------PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1436 Score = 86.7 bits (213), Expect = 4e-17 Identities = 43/87 (49%), Positives = 49/87 (56%), Gaps = 5/87 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GP G G QGPPGS G G G G PG G PGP G G GP + +G +G G Sbjct: 1243 GPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE-----RGEKGEAG 1297 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 PPGA G G+KG G GP+G+PGP G Sbjct: 1298 PPGAAGPPGAKGPPGDDGPKGNPGPVG 1324 Score = 85.9 bits (211), Expect = 6e-17 Identities = 48/105 (45%), Positives = 52/105 (49%), Gaps = 11/105 (10%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 GDK G G G GPPG PG +G G PG+ G G+PGPRG G G D Sbjct: 1138 GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD- 1196 Query: 295 SHIKQGRRGPVGPP------GAPGRDGSKGERGAPGPRGSPGPPG 333 +G RG GPP G PG G KGE G GP G PGPPG Sbjct: 1197 ----EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1237 Score = 85.5 bits (210), Expect = 8e-17 Identities = 43/88 (48%), Positives = 47/88 (53%), Gaps = 2/88 (2%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG G GP G G KG G PG GPPG GP G GP G + G GP Sbjct: 1275 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF--PGDPGPP 1332 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG G+DG G++G G G PGPPG Sbjct: 1333 GEPGPAGQDGVGGDKGEDGDPGQPGPPG 1360 Score = 85.1 bits (209), Expect = 1e-16 Identities = 45/91 (49%), Positives = 52/91 (57%), Gaps = 5/91 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG---PRGSMGPMGPSPDLSHIKQGRRG 303 G PG PG QGPPG G KG+PG G GP G+ G P G GP GP+ S + G +G Sbjct: 1084 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG--SPGEDGDKG 1141 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 +G PG G G KGE G PGP G GP G+ Sbjct: 1142 EIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1172 Score = 84.7 bits (208), Expect = 1e-16 Identities = 44/100 (44%), Positives = 52/100 (52%), Gaps = 11/100 (11%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 G+ T PGP G+ G QGP G GP G G PG PGPPG+ G G+ G Sbjct: 964 GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAG-------- 1015 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 K+G +G GP G G+DG G RG PG RG PG G+ Sbjct: 1016 ---KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA 1052 Score = 83.2 bits (204), Expect = 4e-16 Identities = 46/100 (46%), Positives = 55/100 (55%), Gaps = 20/100 (20%) Query: 246 PGPPGLPGGQGP---PGSPGPKGSPGFPGMPG---PPGQP------GPRGSMGPMGPSPD 293 PGP GLPG QGP PG GP+G PG G+PG PPG P G +G++GP GP Sbjct: 708 PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP--- 764 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 QG G GP G G DG +G +G+ G +G G PG Sbjct: 765 -----QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 799 Score = 82.8 bits (203), Expect = 5e-16 Identities = 50/113 (44%), Positives = 58/113 (51%), Gaps = 15/113 (13%) Query: 235 GDKVLASNTYLPGPPGLP---GGQGPPGSPGPKGSPGFP------GMPGPPGQPGPRGSM 285 G+K GPPG G QGP G PGP+G G P G+PG GQ GP G M Sbjct: 1387 GEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM 1446 Query: 286 GPMGPSPDL-----SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G P L S ++G G +G G PG G KG+RG PG +GSPG G Sbjct: 1447 GPPG-LPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKG 1498 Score = 82.4 bits (202), Expect = 7e-16 Identities = 47/110 (42%), Positives = 58/110 (52%), Gaps = 11/110 (10%) Query: 227 ADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSP---GFPGMPGPPGQPGPRG 283 AD G+ + G+ + G PGLPG +G G GP+G P G GM G G+ GPRG Sbjct: 596 ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRG 655 Query: 284 SMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP +G GP G PGAPG+ G G G PGP+G+ GP G Sbjct: 656 LPGEAGP--------RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 697 Score = 82.4 bits (202), Expect = 7e-16 Identities = 46/101 (45%), Positives = 52/101 (51%), Gaps = 13/101 (12%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------------PGPRGSMGPMG-PSPD 293 GPPG PG QGP G+PG G G PG G G PGP G +G G P P Sbjct: 1159 GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPP 1218 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 + G GP+GPPG PG G +G GA GP+G PG GS Sbjct: 1219 GEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1259 Score = 81.3 bits (199), Expect = 1e-15 Identities = 49/103 (47%), Positives = 53/103 (51%), Gaps = 20/103 (19%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR---- 301 PGP GL G GP G PG G+ G G PGP G PRG GP GP+ K+GR Sbjct: 543 PGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG---PRGVQGPPGPTGKPG--KRGRPGAD 597 Query: 302 --RGPVGPPGA---------PGRDGSKGERGAPGPRGSPGPPG 333 RG G PGA PG G KG RG GP+G PGPPG Sbjct: 598 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 640 Score = 80.9 bits (198), Expect = 2e-15 Identities = 44/95 (46%), Positives = 51/95 (53%), Gaps = 7/95 (7%) Query: 247 GPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMG-PMGPSPDLSHIKQ 299 GP G G GP G PGP KG G PG+PG PG+ GP+GS G P P + + Sbjct: 823 GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGAR 882 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G G GP G G G +G RGA GP G PGP G+ Sbjct: 883 GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGT 917 Score = 80.9 bits (198), Expect = 2e-15 Identities = 45/96 (46%), Positives = 47/96 (48%), Gaps = 17/96 (17%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GP GLPG GP GSPG G G G PG G G +G GP GP G +GPVG Sbjct: 1120 GPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP--------GLQGPVG 1171 Query: 307 PPGAPGRDGSKGERGA---------PGPRGSPGPPG 333 PG G DG G RG G RG PGPPG Sbjct: 1172 APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1207 Score = 80.5 bits (197), Expect = 3e-15 Identities = 49/116 (42%), Positives = 58/116 (50%), Gaps = 28/116 (24%) Query: 246 PGPPGLPGGQGPPGS---------PGP------------KGSPGFPGMPGPPGQPGPRGS 284 PGPPG PG QG PG+ PGP +G PG G+PG G PG +G Sbjct: 999 PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1058 Query: 285 MGPMG-PSPDLSHIKQGRRGPVGPPGAPGRDGSK------GERGAPGPRGSPGPPG 333 GP G P P S ++G G GP G PGR G + GE+GAPG +G GP G Sbjct: 1059 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1114 Score = 79.7 bits (195), Expect = 4e-15 Identities = 42/88 (47%), Positives = 47/88 (53%), Gaps = 1/88 (1%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRGPV 305 GP GL G G G PG +G+PG G GP G PGP GS G G + I GR GP Sbjct: 1033 GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1092 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPG G G+ GE+G GP G G G Sbjct: 1093 GPPGPAGEKGAPGEKGPQGPAGRDGVQG 1120 Score = 77.0 bits (188), Expect = 3e-14 Identities = 44/101 (43%), Positives = 50/101 (49%), Gaps = 17/101 (16%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGM---------PGPPGQPGPRGSMGPMGPSPDLSH 296 PGPPG G QGP G+ GP+G PG G PG G PGP G G GP + Sbjct: 1233 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE--- 1289 Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 +G +G GPPGA G G+KG PG G G PG F Sbjct: 1290 --RGEKGEAGPPGAAGPPGAKGP---PGDDGPKGNPGPVGF 1325 Score = 76.6 bits (187), Expect = 4e-14 Identities = 44/110 (40%), Positives = 51/110 (46%), Gaps = 22/110 (20%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--PSPDLSHIK----- 298 PG GLPG GPPG PG +G G G GPPG GP G GP G + + +K Sbjct: 732 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 791 Query: 299 ---------------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G RG VG G G DG +G +G GP G PGP G Sbjct: 792 KGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSG 841 Score = 74.7 bits (182), Expect = 1e-13 Identities = 44/99 (44%), Positives = 50/99 (50%), Gaps = 7/99 (7%) Query: 246 PGPPGLPGGQGP---PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP-SPDLSHIKQGR 301 PGP G+ G G GS G KG GFPG G G G RG +G +GP D +GR Sbjct: 771 PGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGR 830 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPR---GSPGPPGSFDF 337 GP G PG G+ G KG+ G PG G GP GS F Sbjct: 831 AGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 869 Score = 72.0 bits (175), Expect = 9e-13 Identities = 42/90 (46%), Positives = 48/90 (53%), Gaps = 5/90 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G G G +G G GPKG G G PGP GQ G +G +G G P +QG +G G Sbjct: 811 GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG-LPGYPG-RQGPKGSTG 868 Query: 307 PPGAPGRDGSKGERGA---PGPRGSPGPPG 333 PG PG +G KG RG PGPRG GP G Sbjct: 869 FPGFPGANGEKGARGVAGKPGPRGQRGPTG 898 Score = 71.2 bits (173), Expect = 2e-12 Identities = 40/85 (47%), Positives = 42/85 (49%), Gaps = 15/85 (17%) Query: 254 GQGPPGSPGPKGSPGF--PGM--PGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPG 309 G G G G KG P PGM GPPG GP G MGP G +GP GPPG Sbjct: 430 GHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP-----------PGLQGPTGPPG 478 Query: 310 APGRDGSKGERGAPGPRGSPGPPGS 334 PG G G G PG G PGPPG+ Sbjct: 479 DPGDRGPPGRPGLPGADGLPGPPGT 503 Score = 62.8 bits (151), Expect = 5e-10 Identities = 33/59 (55%), Positives = 36/59 (61%), Gaps = 5/59 (8%) Query: 246 PGPPGLPGGQGP---PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301 PGPPGLPG QGP GS GP G G G+PGPPG PGP G + + P P LS K R Sbjct: 1512 PGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV--IQPLPILSSKKTRR 1568 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 97.4 bits (241), Expect = 2e-20 Identities = 51/106 (48%), Positives = 59/106 (55%), Gaps = 20/106 (18%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQPGPR---------------GSMGP 287 PG G PG +GPPG GPKG+PG FPG PGPPG+PGP G GP Sbjct: 1248 PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP 1307 Query: 288 MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPS + G G GPPGA G +G +GE+GA G G+ GPPG Sbjct: 1308 PGPSGEAG--PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPG 1351 Score = 94.4 bits (233), Expect = 2e-19 Identities = 54/115 (46%), Positives = 58/115 (50%), Gaps = 28/115 (24%) Query: 247 GPPGLPGGQGPPGSPGPKGSP------------GFPGMPGPPGQPGPR------GSMGPM 288 G PGL GG+GP G PGP GSP G PG PGP G PGP G GP Sbjct: 1000 GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ 1059 Query: 289 GPS-PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS---------PGPPG 333 GP+ D G GP GP G+PG DG KGE G PG +GS PGPPG Sbjct: 1060 GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1114 Score = 94.4 bits (233), Expect = 2e-19 Identities = 47/88 (53%), Positives = 50/88 (56%), Gaps = 11/88 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG G QG PG PG KG G G GPPG PGPRG GP G GP Sbjct: 1152 PGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGP-----------NGADGPQ 1200 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPG+ G G GE+G PG G+PGPPG Sbjct: 1201 GPPGSVGSVGGVGEKGEPGEAGNPGPPG 1228 Score = 92.0 bits (227), Expect = 8e-19 Identities = 50/98 (51%), Positives = 56/98 (57%), Gaps = 10/98 (10%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGP-SPDLSHIKQGR 301 PG PG PG G G PGPKG+ G G PGPPGQ PGP+G GP GP P QG+ Sbjct: 621 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 680 Query: 302 RGPV------GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GPPG PG++G GE+GA GP G GP G Sbjct: 681 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIG 718 Score = 92.0 bits (227), Expect = 8e-19 Identities = 51/111 (45%), Positives = 58/111 (52%), Gaps = 29/111 (26%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------------------------PGPR 282 GPPGLPG +G PGS G KG PG G+ GPPG+ PGP Sbjct: 1396 GPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1455 Query: 283 GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G +GP GP P L G +GP G G+ G G KG+ G PGP GSPGPPG Sbjct: 1456 GPLGPPGP-PGL----PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501 Score = 90.9 bits (224), Expect = 2e-18 Identities = 44/88 (50%), Positives = 52/88 (59%), Gaps = 10/88 (11%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305 GP G G +GP G PGPKG+ G G PGPPG+ GP+G GP+G P P +GP Sbjct: 847 GPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP---------KGPP 897 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPG G G G+RG G +G GPPG Sbjct: 898 GPPGKDGLPGHPGQRGETGFQGKTGPPG 925 Score = 90.9 bits (224), Expect = 2e-18 Identities = 49/105 (46%), Positives = 53/105 (50%), Gaps = 8/105 (7%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSP------GPKGSPGFPGMPGPPGQPGPRGSMGPM 288 G + T PGP G GG GPPG P GP+G GFPG GPPG PG G G Sbjct: 850 GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHP 909 Query: 289 GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G + QG+ GP GP G G G GE G G RG PGPPG Sbjct: 910 GQRGETGF--QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 952 Score = 90.9 bits (224), Expect = 2e-18 Identities = 51/106 (48%), Positives = 56/106 (52%), Gaps = 20/106 (18%) Query: 246 PGPPGLPGGQGPPGS---PGPKGSPGFP---GMPGPPGQ------------PGPRGSMGP 287 PGPPG G QGP G PGPKG PG P G+PG PGQ PGP G +GP Sbjct: 873 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 932 Query: 288 MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP+ + I G RG GPPG PG G G G G +G PGP G Sbjct: 933 QGPTGETGPI--GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG 976 Score = 90.1 bits (222), Expect = 3e-18 Identities = 52/119 (43%), Positives = 59/119 (49%), Gaps = 19/119 (15%) Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP---------PGQPGPRGS 284 TGD + G G+PG G PG GPKGS GFPG PG G+PGPRG Sbjct: 783 TGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQ 842 Query: 285 MGPMGP-------SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGA---PGPRGSPGPPG 333 GP GP P +G G GPPG PG G +G +G PGP+G PGPPG Sbjct: 843 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG 901 Score = 89.4 bits (220), Expect = 5e-18 Identities = 51/135 (37%), Positives = 60/135 (44%), Gaps = 31/135 (22%) Query: 230 GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSM---- 285 G + G A + GPPGL G GPPG PG +G PG PG+PG G PGP G+M Sbjct: 398 GMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 457 Query: 286 ------GPMGPSPDLSHIK---------------------QGRRGPVGPPGAPGRDGSKG 318 G GP+ + GR GPVG PG+ G G G Sbjct: 458 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 517 Query: 319 ERGAPGPRGSPGPPG 333 + G GPRG GPPG Sbjct: 518 DPGPQGPRGVQGPPG 532 Score = 89.4 bits (220), Expect = 5e-18 Identities = 45/88 (51%), Positives = 50/88 (56%), Gaps = 4/88 (4%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305 G PG GG+G PG PG KG GF G+PG PG G RG GP G P P +G G + Sbjct: 541 GRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEI 600 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G P G G RG GPRG+PG PG Sbjct: 601 GPRGLP---GEAGPRGLLGPRGTPGAPG 625 Score = 88.6 bits (218), Expect = 9e-18 Identities = 47/97 (48%), Positives = 53/97 (54%), Gaps = 10/97 (10%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMP---GPPGQPGPRGSMGPMG-PSPDLSHIK---- 298 GP GLPG GP G GP+G+PG PG P G G PGP+G+MGP G P P Sbjct: 601 GPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ 660 Query: 299 --QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G +GP+GPPG G G G G PG G PG PG Sbjct: 661 GLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPG 697 Score = 88.6 bits (218), Expect = 9e-18 Identities = 45/102 (44%), Positives = 54/102 (52%), Gaps = 8/102 (7%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292 + GDK + PGPPG G GPPG PG +G PG G G G+ G +G G GP Sbjct: 1292 VGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP-- 1349 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G+ GPVGP G G+ G +G RG PGP G G PG+ Sbjct: 1350 ------PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1385 Score = 86.7 bits (213), Expect = 4e-17 Identities = 43/87 (49%), Positives = 49/87 (56%), Gaps = 5/87 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GP G G QGPPGS G G G G PG G PGP G G GP + +G +G G Sbjct: 1192 GPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE-----RGEKGEAG 1246 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 PPGA G G+KG G GP+G+PGP G Sbjct: 1247 PPGAAGPPGAKGPPGDDGPKGNPGPVG 1273 Score = 85.9 bits (211), Expect = 6e-17 Identities = 48/105 (45%), Positives = 52/105 (49%), Gaps = 11/105 (10%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 GDK G G G GPPG PG +G G PG+ G G+PGPRG G G D Sbjct: 1087 GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD- 1145 Query: 295 SHIKQGRRGPVGPP------GAPGRDGSKGERGAPGPRGSPGPPG 333 +G RG GPP G PG G KGE G GP G PGPPG Sbjct: 1146 ----EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1186 Score = 85.5 bits (210), Expect = 8e-17 Identities = 43/88 (48%), Positives = 47/88 (53%), Gaps = 2/88 (2%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG G GP G G KG G PG GPPG GP G GP G + G GP Sbjct: 1224 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF--PGDPGPP 1281 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG G+DG G++G G G PGPPG Sbjct: 1282 GEPGPAGQDGVGGDKGEDGDPGQPGPPG 1309 Score = 85.1 bits (209), Expect = 1e-16 Identities = 45/91 (49%), Positives = 52/91 (57%), Gaps = 5/91 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG---PRGSMGPMGPSPDLSHIKQGRRG 303 G PG PG QGPPG G KG+PG G GP G+ G P G GP GP+ S + G +G Sbjct: 1033 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG--SPGEDGDKG 1090 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 +G PG G G KGE G PGP G GP G+ Sbjct: 1091 EIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1121 Score = 84.7 bits (208), Expect = 1e-16 Identities = 44/100 (44%), Positives = 52/100 (52%), Gaps = 11/100 (11%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 G+ T PGP G+ G QGP G GP G G PG PGPPG+ G G+ G Sbjct: 913 GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAG-------- 964 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 K+G +G GP G G+DG G RG PG RG PG G+ Sbjct: 965 ---KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA 1001 Score = 83.2 bits (204), Expect = 4e-16 Identities = 46/100 (46%), Positives = 55/100 (55%), Gaps = 20/100 (20%) Query: 246 PGPPGLPGGQGP---PGSPGPKGSPGFPGMPG---PPGQP------GPRGSMGPMGPSPD 293 PGP GLPG QGP PG GP+G PG G+PG PPG P G +G++GP GP Sbjct: 657 PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP--- 713 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 QG G GP G G DG +G +G+ G +G G PG Sbjct: 714 -----QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 748 Score = 82.8 bits (203), Expect = 5e-16 Identities = 50/113 (44%), Positives = 58/113 (51%), Gaps = 15/113 (13%) Query: 235 GDKVLASNTYLPGPPGLP---GGQGPPGSPGPKGSPGFP------GMPGPPGQPGPRGSM 285 G+K GPPG G QGP G PGP+G G P G+PG GQ GP G M Sbjct: 1336 GEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM 1395 Query: 286 GPMGPSPDL-----SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G P L S ++G G +G G PG G KG+RG PG +GSPG G Sbjct: 1396 GPPG-LPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKG 1447 Score = 82.4 bits (202), Expect = 7e-16 Identities = 47/110 (42%), Positives = 58/110 (52%), Gaps = 11/110 (10%) Query: 227 ADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSP---GFPGMPGPPGQPGPRG 283 AD G+ + G+ + G PGLPG +G G GP+G P G GM G G+ GPRG Sbjct: 545 ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRG 604 Query: 284 SMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP +G GP G PGAPG+ G G G PGP+G+ GP G Sbjct: 605 LPGEAGP--------RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 646 Score = 82.4 bits (202), Expect = 7e-16 Identities = 46/101 (45%), Positives = 52/101 (51%), Gaps = 13/101 (12%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------------PGPRGSMGPMG-PSPD 293 GPPG PG QGP G+PG G G PG G G PGP G +G G P P Sbjct: 1108 GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPP 1167 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 + G GP+GPPG PG G +G GA GP+G PG GS Sbjct: 1168 GEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1208 Score = 81.3 bits (199), Expect = 1e-15 Identities = 49/103 (47%), Positives = 53/103 (51%), Gaps = 20/103 (19%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR---- 301 PGP GL G GP G PG G+ G G PGP G PRG GP GP+ K+GR Sbjct: 492 PGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG---PRGVQGPPGPTGKPG--KRGRPGAD 546 Query: 302 --RGPVGPPGA---------PGRDGSKGERGAPGPRGSPGPPG 333 RG G PGA PG G KG RG GP+G PGPPG Sbjct: 547 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 589 Score = 80.9 bits (198), Expect = 2e-15 Identities = 44/95 (46%), Positives = 51/95 (53%), Gaps = 7/95 (7%) Query: 247 GPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMG-PMGPSPDLSHIKQ 299 GP G G GP G PGP KG G PG+PG PG+ GP+GS G P P + + Sbjct: 772 GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGAR 831 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G G GP G G G +G RGA GP G PGP G+ Sbjct: 832 GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGT 866 Score = 80.9 bits (198), Expect = 2e-15 Identities = 45/96 (46%), Positives = 47/96 (48%), Gaps = 17/96 (17%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GP GLPG GP GSPG G G G PG G G +G GP GP G +GPVG Sbjct: 1069 GPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP--------GLQGPVG 1120 Query: 307 PPGAPGRDGSKGERGA---------PGPRGSPGPPG 333 PG G DG G RG G RG PGPPG Sbjct: 1121 APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1156 Score = 80.5 bits (197), Expect = 3e-15 Identities = 49/116 (42%), Positives = 58/116 (50%), Gaps = 28/116 (24%) Query: 246 PGPPGLPGGQGPPGS---------PGP------------KGSPGFPGMPGPPGQPGPRGS 284 PGPPG PG QG PG+ PGP +G PG G+PG G PG +G Sbjct: 948 PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1007 Query: 285 MGPMG-PSPDLSHIKQGRRGPVGPPGAPGRDGSK------GERGAPGPRGSPGPPG 333 GP G P P S ++G G GP G PGR G + GE+GAPG +G GP G Sbjct: 1008 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1063 Score = 79.7 bits (195), Expect = 4e-15 Identities = 42/88 (47%), Positives = 47/88 (53%), Gaps = 1/88 (1%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRGPV 305 GP GL G G G PG +G+PG G GP G PGP GS G G + I GR GP Sbjct: 982 GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1041 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPG G G+ GE+G GP G G G Sbjct: 1042 GPPGPAGEKGAPGEKGPQGPAGRDGVQG 1069 Score = 77.0 bits (188), Expect = 3e-14 Identities = 44/101 (43%), Positives = 50/101 (49%), Gaps = 17/101 (16%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGM---------PGPPGQPGPRGSMGPMGPSPDLSH 296 PGPPG G QGP G+ GP+G PG G PG G PGP G G GP + Sbjct: 1182 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE--- 1238 Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 +G +G GPPGA G G+KG PG G G PG F Sbjct: 1239 --RGEKGEAGPPGAAGPPGAKGP---PGDDGPKGNPGPVGF 1274 Score = 76.6 bits (187), Expect = 4e-14 Identities = 44/110 (40%), Positives = 51/110 (46%), Gaps = 22/110 (20%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--PSPDLSHIK----- 298 PG GLPG GPPG PG +G G G GPPG GP G GP G + + +K Sbjct: 681 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 740 Query: 299 ---------------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G RG VG G G DG +G +G GP G PGP G Sbjct: 741 KGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSG 790 Score = 74.7 bits (182), Expect = 1e-13 Identities = 44/99 (44%), Positives = 50/99 (50%), Gaps = 7/99 (7%) Query: 246 PGPPGLPGGQGP---PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP-SPDLSHIKQGR 301 PGP G+ G G GS G KG GFPG G G G RG +G +GP D +GR Sbjct: 720 PGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGR 779 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPR---GSPGPPGSFDF 337 GP G PG G+ G KG+ G PG G GP GS F Sbjct: 780 AGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 818 Score = 72.0 bits (175), Expect = 9e-13 Identities = 42/90 (46%), Positives = 48/90 (53%), Gaps = 5/90 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G G G +G G GPKG G G PGP GQ G +G +G G P +QG +G G Sbjct: 760 GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG-LPGYPG-RQGPKGSTG 817 Query: 307 PPGAPGRDGSKGERGA---PGPRGSPGPPG 333 PG PG +G KG RG PGPRG GP G Sbjct: 818 FPGFPGANGEKGARGVAGKPGPRGQRGPTG 847 Score = 71.2 bits (173), Expect = 2e-12 Identities = 40/85 (47%), Positives = 42/85 (49%), Gaps = 15/85 (17%) Query: 254 GQGPPGSPGPKGSPGF--PGM--PGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPG 309 G G G G KG P PGM GPPG GP G MGP G +GP GPPG Sbjct: 379 GHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP-----------PGLQGPTGPPG 427 Query: 310 APGRDGSKGERGAPGPRGSPGPPGS 334 PG G G G PG G PGPPG+ Sbjct: 428 DPGDRGPPGRPGLPGADGLPGPPGT 452 Score = 62.8 bits (151), Expect = 5e-10 Identities = 33/59 (55%), Positives = 36/59 (61%), Gaps = 5/59 (8%) Query: 246 PGPPGLPGGQGP---PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301 PGPPGLPG QGP GS GP G G G+PGPPG PGP G + + P P LS K R Sbjct: 1461 PGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV--IQPLPILSSKKTRR 1517 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 97.4 bits (241), Expect = 2e-20 Identities = 51/106 (48%), Positives = 59/106 (55%), Gaps = 20/106 (18%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQPGPR---------------GSMGP 287 PG G PG +GPPG GPKG+PG FPG PGPPG+PGP G GP Sbjct: 1287 PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP 1346 Query: 288 MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPS + G G GPPGA G +G +GE+GA G G+ GPPG Sbjct: 1347 PGPSGEAG--PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPG 1390 Score = 94.4 bits (233), Expect = 2e-19 Identities = 54/115 (46%), Positives = 58/115 (50%), Gaps = 28/115 (24%) Query: 247 GPPGLPGGQGPPGSPGPKGSP------------GFPGMPGPPGQPGPR------GSMGPM 288 G PGL GG+GP G PGP GSP G PG PGP G PGP G GP Sbjct: 1039 GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ 1098 Query: 289 GPS-PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS---------PGPPG 333 GP+ D G GP GP G+PG DG KGE G PG +GS PGPPG Sbjct: 1099 GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1153 Score = 94.4 bits (233), Expect = 2e-19 Identities = 47/88 (53%), Positives = 50/88 (56%), Gaps = 11/88 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG G QG PG PG KG G G GPPG PGPRG GP G GP Sbjct: 1191 PGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGP-----------NGADGPQ 1239 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPG+ G G GE+G PG G+PGPPG Sbjct: 1240 GPPGSVGSVGGVGEKGEPGEAGNPGPPG 1267 Score = 92.0 bits (227), Expect = 8e-19 Identities = 50/98 (51%), Positives = 56/98 (57%), Gaps = 10/98 (10%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGP-SPDLSHIKQGR 301 PG PG PG G G PGPKG+ G G PGPPGQ PGP+G GP GP P QG+ Sbjct: 660 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 719 Query: 302 RGPV------GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GPPG PG++G GE+GA GP G GP G Sbjct: 720 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIG 757 Score = 92.0 bits (227), Expect = 8e-19 Identities = 51/111 (45%), Positives = 58/111 (52%), Gaps = 29/111 (26%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------------------------PGPR 282 GPPGLPG +G PGS G KG PG G+ GPPG+ PGP Sbjct: 1435 GPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1494 Query: 283 GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G +GP GP P L G +GP G G+ G G KG+ G PGP GSPGPPG Sbjct: 1495 GPLGPPGP-PGL----PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540 Score = 90.9 bits (224), Expect = 2e-18 Identities = 44/88 (50%), Positives = 52/88 (59%), Gaps = 10/88 (11%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305 GP G G +GP G PGPKG+ G G PGPPG+ GP+G GP+G P P +GP Sbjct: 886 GPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP---------KGPP 936 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPG G G G+RG G +G GPPG Sbjct: 937 GPPGKDGLPGHPGQRGETGFQGKTGPPG 964 Score = 90.9 bits (224), Expect = 2e-18 Identities = 49/105 (46%), Positives = 53/105 (50%), Gaps = 8/105 (7%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSP------GPKGSPGFPGMPGPPGQPGPRGSMGPM 288 G + T PGP G GG GPPG P GP+G GFPG GPPG PG G G Sbjct: 889 GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHP 948 Query: 289 GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G + QG+ GP GP G G G GE G G RG PGPPG Sbjct: 949 GQRGETGF--QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 991 Score = 90.9 bits (224), Expect = 2e-18 Identities = 51/106 (48%), Positives = 56/106 (52%), Gaps = 20/106 (18%) Query: 246 PGPPGLPGGQGPPGS---PGPKGSPGFP---GMPGPPGQ------------PGPRGSMGP 287 PGPPG G QGP G PGPKG PG P G+PG PGQ PGP G +GP Sbjct: 912 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 971 Query: 288 MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP+ + I G RG GPPG PG G G G G +G PGP G Sbjct: 972 QGPTGETGPI--GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG 1015 Score = 90.1 bits (222), Expect = 3e-18 Identities = 52/119 (43%), Positives = 59/119 (49%), Gaps = 19/119 (15%) Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP---------PGQPGPRGS 284 TGD + G G+PG G PG GPKGS GFPG PG G+PGPRG Sbjct: 822 TGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQ 881 Query: 285 MGPMGP-------SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGA---PGPRGSPGPPG 333 GP GP P +G G GPPG PG G +G +G PGP+G PGPPG Sbjct: 882 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG 940 Score = 89.4 bits (220), Expect = 5e-18 Identities = 51/135 (37%), Positives = 60/135 (44%), Gaps = 31/135 (22%) Query: 230 GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSM---- 285 G + G A + GPPGL G GPPG PG +G PG PG+PG G PGP G+M Sbjct: 437 GMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 496 Query: 286 ------GPMGPSPDLSHIK---------------------QGRRGPVGPPGAPGRDGSKG 318 G GP+ + GR GPVG PG+ G G G Sbjct: 497 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 556 Query: 319 ERGAPGPRGSPGPPG 333 + G GPRG GPPG Sbjct: 557 DPGPQGPRGVQGPPG 571 Score = 89.4 bits (220), Expect = 5e-18 Identities = 45/88 (51%), Positives = 50/88 (56%), Gaps = 4/88 (4%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305 G PG GG+G PG PG KG GF G+PG PG G RG GP G P P +G G + Sbjct: 580 GRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEI 639 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G P G G RG GPRG+PG PG Sbjct: 640 GPRGLP---GEAGPRGLLGPRGTPGAPG 664 Score = 88.6 bits (218), Expect = 9e-18 Identities = 47/97 (48%), Positives = 53/97 (54%), Gaps = 10/97 (10%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMP---GPPGQPGPRGSMGPMG-PSPDLSHIK---- 298 GP GLPG GP G GP+G+PG PG P G G PGP+G+MGP G P P Sbjct: 640 GPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ 699 Query: 299 --QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G +GP+GPPG G G G G PG G PG PG Sbjct: 700 GLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPG 736 Score = 88.6 bits (218), Expect = 9e-18 Identities = 45/102 (44%), Positives = 54/102 (52%), Gaps = 8/102 (7%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292 + GDK + PGPPG G GPPG PG +G PG G G G+ G +G G GP Sbjct: 1331 VGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP-- 1388 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G+ GPVGP G G+ G +G RG PGP G G PG+ Sbjct: 1389 ------PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1424 Score = 86.7 bits (213), Expect = 4e-17 Identities = 43/87 (49%), Positives = 49/87 (56%), Gaps = 5/87 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GP G G QGPPGS G G G G PG G PGP G G GP + +G +G G Sbjct: 1231 GPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE-----RGEKGEAG 1285 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 PPGA G G+KG G GP+G+PGP G Sbjct: 1286 PPGAAGPPGAKGPPGDDGPKGNPGPVG 1312 Score = 85.9 bits (211), Expect = 6e-17 Identities = 48/105 (45%), Positives = 52/105 (49%), Gaps = 11/105 (10%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 GDK G G G GPPG PG +G G PG+ G G+PGPRG G G D Sbjct: 1126 GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD- 1184 Query: 295 SHIKQGRRGPVGPP------GAPGRDGSKGERGAPGPRGSPGPPG 333 +G RG GPP G PG G KGE G GP G PGPPG Sbjct: 1185 ----EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1225 Score = 85.5 bits (210), Expect = 8e-17 Identities = 43/88 (48%), Positives = 47/88 (53%), Gaps = 2/88 (2%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG G GP G G KG G PG GPPG GP G GP G + G GP Sbjct: 1263 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF--PGDPGPP 1320 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG G+DG G++G G G PGPPG Sbjct: 1321 GEPGPAGQDGVGGDKGEDGDPGQPGPPG 1348 Score = 85.1 bits (209), Expect = 1e-16 Identities = 45/91 (49%), Positives = 52/91 (57%), Gaps = 5/91 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG---PRGSMGPMGPSPDLSHIKQGRRG 303 G PG PG QGPPG G KG+PG G GP G+ G P G GP GP+ S + G +G Sbjct: 1072 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG--SPGEDGDKG 1129 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 +G PG G G KGE G PGP G GP G+ Sbjct: 1130 EIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1160 Score = 84.7 bits (208), Expect = 1e-16 Identities = 44/100 (44%), Positives = 52/100 (52%), Gaps = 11/100 (11%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 G+ T PGP G+ G QGP G GP G G PG PGPPG+ G G+ G Sbjct: 952 GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAG-------- 1003 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 K+G +G GP G G+DG G RG PG RG PG G+ Sbjct: 1004 ---KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA 1040 Score = 83.2 bits (204), Expect = 4e-16 Identities = 46/100 (46%), Positives = 55/100 (55%), Gaps = 20/100 (20%) Query: 246 PGPPGLPGGQGP---PGSPGPKGSPGFPGMPG---PPGQP------GPRGSMGPMGPSPD 293 PGP GLPG QGP PG GP+G PG G+PG PPG P G +G++GP GP Sbjct: 696 PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP--- 752 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 QG G GP G G DG +G +G+ G +G G PG Sbjct: 753 -----QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 787 Score = 82.8 bits (203), Expect = 5e-16 Identities = 50/113 (44%), Positives = 58/113 (51%), Gaps = 15/113 (13%) Query: 235 GDKVLASNTYLPGPPGLP---GGQGPPGSPGPKGSPGFP------GMPGPPGQPGPRGSM 285 G+K GPPG G QGP G PGP+G G P G+PG GQ GP G M Sbjct: 1375 GEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM 1434 Query: 286 GPMGPSPDL-----SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G P L S ++G G +G G PG G KG+RG PG +GSPG G Sbjct: 1435 GPPG-LPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKG 1486 Score = 82.4 bits (202), Expect = 7e-16 Identities = 47/110 (42%), Positives = 58/110 (52%), Gaps = 11/110 (10%) Query: 227 ADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSP---GFPGMPGPPGQPGPRG 283 AD G+ + G+ + G PGLPG +G G GP+G P G GM G G+ GPRG Sbjct: 584 ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRG 643 Query: 284 SMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP +G GP G PGAPG+ G G G PGP+G+ GP G Sbjct: 644 LPGEAGP--------RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 685 Score = 82.4 bits (202), Expect = 7e-16 Identities = 46/101 (45%), Positives = 52/101 (51%), Gaps = 13/101 (12%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------------PGPRGSMGPMG-PSPD 293 GPPG PG QGP G+PG G G PG G G PGP G +G G P P Sbjct: 1147 GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPP 1206 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 + G GP+GPPG PG G +G GA GP+G PG GS Sbjct: 1207 GEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1247 Score = 81.3 bits (199), Expect = 1e-15 Identities = 49/103 (47%), Positives = 53/103 (51%), Gaps = 20/103 (19%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR---- 301 PGP GL G GP G PG G+ G G PGP G PRG GP GP+ K+GR Sbjct: 531 PGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG---PRGVQGPPGPTGKPG--KRGRPGAD 585 Query: 302 --RGPVGPPGA---------PGRDGSKGERGAPGPRGSPGPPG 333 RG G PGA PG G KG RG GP+G PGPPG Sbjct: 586 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 628 Score = 80.9 bits (198), Expect = 2e-15 Identities = 44/95 (46%), Positives = 51/95 (53%), Gaps = 7/95 (7%) Query: 247 GPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMG-PMGPSPDLSHIKQ 299 GP G G GP G PGP KG G PG+PG PG+ GP+GS G P P + + Sbjct: 811 GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGAR 870 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G G GP G G G +G RGA GP G PGP G+ Sbjct: 871 GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGT 905 Score = 80.9 bits (198), Expect = 2e-15 Identities = 45/96 (46%), Positives = 47/96 (48%), Gaps = 17/96 (17%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GP GLPG GP GSPG G G G PG G G +G GP GP G +GPVG Sbjct: 1108 GPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP--------GLQGPVG 1159 Query: 307 PPGAPGRDGSKGERGA---------PGPRGSPGPPG 333 PG G DG G RG G RG PGPPG Sbjct: 1160 APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1195 Score = 80.5 bits (197), Expect = 3e-15 Identities = 49/116 (42%), Positives = 58/116 (50%), Gaps = 28/116 (24%) Query: 246 PGPPGLPGGQGPPGS---------PGP------------KGSPGFPGMPGPPGQPGPRGS 284 PGPPG PG QG PG+ PGP +G PG G+PG G PG +G Sbjct: 987 PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1046 Query: 285 MGPMG-PSPDLSHIKQGRRGPVGPPGAPGRDGSK------GERGAPGPRGSPGPPG 333 GP G P P S ++G G GP G PGR G + GE+GAPG +G GP G Sbjct: 1047 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1102 Score = 79.7 bits (195), Expect = 4e-15 Identities = 42/88 (47%), Positives = 47/88 (53%), Gaps = 1/88 (1%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRGPV 305 GP GL G G G PG +G+PG G GP G PGP GS G G + I GR GP Sbjct: 1021 GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1080 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPG G G+ GE+G GP G G G Sbjct: 1081 GPPGPAGEKGAPGEKGPQGPAGRDGVQG 1108 Score = 77.0 bits (188), Expect = 3e-14 Identities = 44/101 (43%), Positives = 50/101 (49%), Gaps = 17/101 (16%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGM---------PGPPGQPGPRGSMGPMGPSPDLSH 296 PGPPG G QGP G+ GP+G PG G PG G PGP G G GP + Sbjct: 1221 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE--- 1277 Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 +G +G GPPGA G G+KG PG G G PG F Sbjct: 1278 --RGEKGEAGPPGAAGPPGAKGP---PGDDGPKGNPGPVGF 1313 Score = 76.6 bits (187), Expect = 4e-14 Identities = 44/110 (40%), Positives = 51/110 (46%), Gaps = 22/110 (20%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--PSPDLSHIK----- 298 PG GLPG GPPG PG +G G G GPPG GP G GP G + + +K Sbjct: 720 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 779 Query: 299 ---------------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G RG VG G G DG +G +G GP G PGP G Sbjct: 780 KGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSG 829 Score = 74.7 bits (182), Expect = 1e-13 Identities = 44/99 (44%), Positives = 50/99 (50%), Gaps = 7/99 (7%) Query: 246 PGPPGLPGGQGP---PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP-SPDLSHIKQGR 301 PGP G+ G G GS G KG GFPG G G G RG +G +GP D +GR Sbjct: 759 PGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGR 818 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPR---GSPGPPGSFDF 337 GP G PG G+ G KG+ G PG G GP GS F Sbjct: 819 AGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 857 Score = 72.0 bits (175), Expect = 9e-13 Identities = 42/90 (46%), Positives = 48/90 (53%), Gaps = 5/90 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G G G +G G GPKG G G PGP GQ G +G +G G P +QG +G G Sbjct: 799 GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG-LPGYPG-RQGPKGSTG 856 Query: 307 PPGAPGRDGSKGERGA---PGPRGSPGPPG 333 PG PG +G KG RG PGPRG GP G Sbjct: 857 FPGFPGANGEKGARGVAGKPGPRGQRGPTG 886 Score = 71.2 bits (173), Expect = 2e-12 Identities = 40/85 (47%), Positives = 42/85 (49%), Gaps = 15/85 (17%) Query: 254 GQGPPGSPGPKGSPGF--PGM--PGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPG 309 G G G G KG P PGM GPPG GP G MGP G +GP GPPG Sbjct: 418 GHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP-----------PGLQGPTGPPG 466 Query: 310 APGRDGSKGERGAPGPRGSPGPPGS 334 PG G G G PG G PGPPG+ Sbjct: 467 DPGDRGPPGRPGLPGADGLPGPPGT 491 Score = 62.8 bits (151), Expect = 5e-10 Identities = 33/59 (55%), Positives = 36/59 (61%), Gaps = 5/59 (8%) Query: 246 PGPPGLPGGQGP---PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301 PGPPGLPG QGP GS GP G G G+PGPPG PGP G + + P P LS K R Sbjct: 1500 PGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV--IQPLPILSSKKTRR 1556 >gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] Length = 1073 Score = 97.4 bits (241), Expect = 2e-20 Identities = 50/99 (50%), Positives = 56/99 (56%), Gaps = 10/99 (10%) Query: 246 PGPPGLPGGQGPPGSPGPKGS---PGFPGMPGPPGQPGPRGSMGPMG-------PSPDLS 295 PGPPG PG G PG PGP+G+ PGF G G G PGPRG G MG P D Sbjct: 698 PGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGD 757 Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G +GP GP G PG++GS G G PGP G+PG GS Sbjct: 758 TGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGS 796 Score = 95.9 bits (237), Expect = 6e-20 Identities = 47/92 (51%), Positives = 55/92 (59%), Gaps = 6/92 (6%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPP---GQPGPRGSMGPMGPS--PDLSHIKQGR 301 G PG+PG GPPG+PGP G+ G G GPP G PG G GP GPS P + ++G+ Sbjct: 633 GHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG-EEGK 691 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G PG PG G GE G PGP G+ GPPG Sbjct: 692 EGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG 723 Score = 90.9 bits (224), Expect = 2e-18 Identities = 48/99 (48%), Positives = 54/99 (54%), Gaps = 14/99 (14%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGS------------MGPMGPSPDL 294 GP G G QGP G PG GSPG PG PGP G PG +GS +GP GP + Sbjct: 759 GPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEP 818 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 ++G G G PG PG G KGERG PG +G GPPG Sbjct: 819 G--EKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPG 855 Score = 89.4 bits (220), Expect = 5e-18 Identities = 47/100 (47%), Positives = 53/100 (53%), Gaps = 13/100 (13%) Query: 247 GPPGLPGGQGPPGSPGPKGS------PGFPGMPGPPGQPGPRGSMGPMGP-SPDLSHIKQ 299 GPPG G G G+PGP+G PG G+PG G GP G GP GP P + Sbjct: 720 GPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 779 Query: 300 GRRGPVGPPGAPGRDGSKGERGAP------GPRGSPGPPG 333 G G GP G PG+ GSKGE G+P GPRG PG PG Sbjct: 780 GSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPG 819 Score = 87.4 bits (215), Expect = 2e-17 Identities = 49/102 (48%), Positives = 53/102 (51%), Gaps = 11/102 (10%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 GD L L G PG G QGP G PG KG G G PG G PG G +G GPS Sbjct: 356 GDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPS--- 412 Query: 295 SHIKQGRRGPVGPP---GAPGRDGSKGERGAPGPRGSPGPPG 333 G G VG P G PG+DG +GE+GA G GSPGP G Sbjct: 413 -----GPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVG 449 Score = 85.1 bits (209), Expect = 1e-16 Identities = 46/109 (42%), Positives = 55/109 (50%), Gaps = 9/109 (8%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQG-------PPGSPGPKGSPGFPGMPGPPGQPGPRGSM 285 + GD+ GPPGLPG PG GPKG G PG+PG PG G G + Sbjct: 314 LKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGEL 373 Query: 286 GPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 GP GP+ +G+ G G PGA G G+ G GAPGP G PG G+ Sbjct: 374 GPQGPTGPPG--AKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGA 420 Score = 85.1 bits (209), Expect = 1e-16 Identities = 45/93 (48%), Positives = 51/93 (54%), Gaps = 4/93 (4%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRG 303 +PG PG G +G G GP G PG PG+ GP G G RG+ G +G D H G G Sbjct: 583 VPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMG 642 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSP---GPPG 333 P G PG PG DG G G PG +GSP GPPG Sbjct: 643 PPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPG 675 Score = 85.1 bits (209), Expect = 1e-16 Identities = 44/93 (47%), Positives = 47/93 (50%), Gaps = 5/93 (5%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG PG G PG GP G PG PG G G GP G G G D G RG + Sbjct: 946 PGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEM 1005 Query: 306 GPPGAPGRDGSKGER-----GAPGPRGSPGPPG 333 GPPG PG+ G G G PGP+G GP G Sbjct: 1006 GPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAG 1038 Score = 84.3 bits (207), Expect = 2e-16 Identities = 45/95 (47%), Positives = 50/95 (52%), Gaps = 14/95 (14%) Query: 246 PGPPGLPG------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299 PGPPGLPG +G PG PG +G+ G G GPPG PGP G GP G Q Sbjct: 566 PGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQG--------SQ 617 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G RG G G G G G G GP G+PGPPG+ Sbjct: 618 GERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGA 652 Score = 84.3 bits (207), Expect = 2e-16 Identities = 43/88 (48%), Positives = 49/88 (55%), Gaps = 5/88 (5%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG PG G +GPPG PG KG PG G+PG PG+PG +G G G D +G G Sbjct: 803 PGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGD-----KGPPGGK 857 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG PG G KG G GP+G PG G Sbjct: 858 GQPGDPGIPGHKGHTGLMGPQGLPGENG 885 Score = 82.0 bits (201), Expect = 9e-16 Identities = 49/106 (46%), Positives = 54/106 (50%), Gaps = 12/106 (11%) Query: 240 ASNTYLPGPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296 A N PG G PG GPPGS PG +G+PG G G G G GS GP+GP D Sbjct: 397 AGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGA 456 Query: 297 I---------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 K G G G PG PG G+KG+RGAPG GSPG G Sbjct: 457 PGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRG 502 Score = 82.0 bits (201), Expect = 9e-16 Identities = 46/102 (45%), Positives = 55/102 (53%), Gaps = 4/102 (3%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGP--KGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292 G+K A PGP G G G PG PGP KG G PG+ G PG PGP G+ G G +P Sbjct: 434 GEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRG-AP 492 Query: 293 DLSHIKQGRRGP-VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 + R P +G G PG G G++G+PG RG PG PG Sbjct: 493 GIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPG 534 Score = 80.9 bits (198), Expect = 2e-15 Identities = 54/146 (36%), Positives = 69/146 (47%), Gaps = 42/146 (28%) Query: 230 GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGM-----PGPPGQPGPRGS 284 GK G+ L + LPGP G G +G PG PG GS G PG+ PGP G PG +GS Sbjct: 464 GKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGS 523 Query: 285 ---------MGPMGP----------SP-DLSHIKQ-----------------GRRGPVGP 307 GP GP SP D++ + + G +G G Sbjct: 524 PGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGV 583 Query: 308 PGAPGRDGSKGERGAPGPRGSPGPPG 333 PG PGR+G++G++G GP G PGPPG Sbjct: 584 PGKPGREGTEGKKGEAGPPGLPGPPG 609 Score = 80.9 bits (198), Expect = 2e-15 Identities = 51/134 (38%), Positives = 57/134 (42%), Gaps = 33/134 (24%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292 I GDK PG PG+PG +G G GP+G PG G GPPG PG G G G SP Sbjct: 847 IKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESP 906 Query: 293 DLSHIK------------------------------QGRRGPVGPP---GAPGRDGSKGE 319 + ++ QGR GP GPP G PGR G GE Sbjct: 907 SMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGE 966 Query: 320 RGAPGPRGSPGPPG 333 G PG G GP G Sbjct: 967 PGRPGQGGLEGPSG 980 Score = 79.7 bits (195), Expect = 4e-15 Identities = 42/99 (42%), Positives = 51/99 (51%), Gaps = 10/99 (10%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG---------PSPDLS 295 LPG PG PG +G G G KG G PG+ G G+ G G GP G P P + Sbjct: 287 LPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMP 346 Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 +QG +G G PG PG G +G G GP+G GPPG+ Sbjct: 347 G-EQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGA 384 Score = 79.7 bits (195), Expect = 4e-15 Identities = 48/110 (43%), Positives = 54/110 (49%), Gaps = 7/110 (6%) Query: 246 PGPPGLPG--GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303 PG PGLPG G+G G PG +GSPG PG G G G G G G D G G Sbjct: 454 PGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPG 513 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLL-----LMLADIRND 348 P GPPG G GS+G G PGP+G G G L L+ D+ ND Sbjct: 514 PSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCND 563 Score = 79.7 bits (195), Expect = 4e-15 Identities = 42/86 (48%), Positives = 47/86 (54%), Gaps = 3/86 (3%) Query: 248 PPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGP 307 P + QG PG PGP G G PG GP G+PG G G GPS + +G RG G Sbjct: 936 PAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIG--PKGERGAKGD 993 Query: 308 PGAPGRDGSKGERGAPGPRGSPGPPG 333 PGAPG G +GE G PG G PG PG Sbjct: 994 PGAPG-VGLRGEMGPPGIPGQPGEPG 1018 Score = 75.5 bits (184), Expect = 8e-14 Identities = 46/123 (37%), Positives = 53/123 (43%), Gaps = 20/123 (16%) Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP 290 K + G+ LPG PGL G G G G G G G+PG PG PG RG G G Sbjct: 246 KQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGE 305 Query: 291 SPDL-------SHIKQGRRGPVGPPG-------------APGRDGSKGERGAPGPRGSPG 330 +L ++G GP GPPG PG G KGE+G PG G PG Sbjct: 306 KGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPG 365 Query: 331 PPG 333 G Sbjct: 366 LQG 368 Score = 73.6 bits (179), Expect = 3e-13 Identities = 41/90 (45%), Positives = 47/90 (52%), Gaps = 8/90 (8%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGPS 291 G+K + +PG PG PG +G G PG KG G PG G PG PG +G G MGP Sbjct: 819 GEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQ 878 Query: 292 PDLSHIKQGRRGPVGPPGAPGRDGSKGERG 321 G GPVGPPG PG+ G G RG Sbjct: 879 G-----LPGENGPVGPPGPPGQPGFPGLRG 903 Score = 70.5 bits (171), Expect = 3e-12 Identities = 49/132 (37%), Positives = 56/132 (42%), Gaps = 40/132 (30%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGM------------------------------PGPP 276 GPPG G G GSPG +G PGFPG PGPP Sbjct: 510 GPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPP 569 Query: 277 GQPGPRGSMGPMG----PSPDLSHIKQGRRGPVG---PPGAPGRDGSKGERGAPGP---R 326 G PG G G G P + + K+G GP G PPG G GS+GERGA G + Sbjct: 570 GLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQK 629 Query: 327 GSPGPPGSFDFL 338 G G PG F+ Sbjct: 630 GDQGHPGVPGFM 641 Score = 63.9 bits (154), Expect = 2e-10 Identities = 40/104 (38%), Positives = 51/104 (49%), Gaps = 11/104 (10%) Query: 238 VLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP------PGQPGPRGSMG-PMGP 290 +LA+ T PGL G PG G G PG PG+ G G+PG +G G P P Sbjct: 236 ILAAKT----APGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAP 291 Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 ++G +G G G PG G +GE+G GP G PG PG+ Sbjct: 292 GFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGT 335 Score = 63.2 bits (152), Expect = 4e-10 Identities = 37/92 (40%), Positives = 43/92 (46%), Gaps = 23/92 (25%) Query: 247 GPPGLPGGQGPPGSPGP--KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 GP G G +G PG+PG +G G PG+PG PG+PG + K G Sbjct: 983 GPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG---------------YAKDGL--- 1024 Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPGSFD 336 PG PG G G G PG G PGPPG D Sbjct: 1025 ---PGIPGPQGETGPAGHPGLPGPPGPPGQCD 1053 Score = 50.8 bits (120), Expect = 2e-06 Identities = 24/41 (58%), Positives = 24/41 (58%), Gaps = 5/41 (12%) Query: 246 PGPPG-----LPGGQGPPGSPGPKGSPGFPGMPGPPGQPGP 281 PG PG LPG GP G GP G PG PG PGPPGQ P Sbjct: 1014 PGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDP 1054 Score = 50.4 bits (119), Expect = 3e-06 Identities = 29/62 (46%), Positives = 31/62 (50%), Gaps = 16/62 (25%) Query: 246 PGPPG--LPGGQGPPGSPGPKGSPGF-----PGMPGP---------PGQPGPRGSMGPMG 289 PG PG L G GPPG PG G PG+ PG+PGP PG PGP G G Sbjct: 994 PGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCD 1053 Query: 290 PS 291 PS Sbjct: 1054 PS 1055 Score = 50.1 bits (118), Expect = 4e-06 Identities = 24/45 (53%), Positives = 26/45 (57%), Gaps = 2/45 (4%) Query: 245 LPGPPGLPG--GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGP 287 +PG PG PG G PG PGP+G G G PG PG PGP G P Sbjct: 1010 IPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDP 1054 Score = 35.8 bits (81), Expect = 0.071 Identities = 25/68 (36%), Positives = 29/68 (42%), Gaps = 17/68 (25%) Query: 270 PGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSP 329 PG+ G+PG RG G G K G RG +G G GR G KGE Sbjct: 243 PGLKQLNGEPGERGEDGLPG--------KPGLRGEIGEQGLAGRPGEKGE---------A 285 Query: 330 GPPGSFDF 337 G PG+ F Sbjct: 286 GLPGAPGF 293 Score = 31.6 bits (70), Expect = 1.3 Identities = 14/31 (45%), Positives = 15/31 (48%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPG 277 G PGLPG GPPG P F + PG Sbjct: 1038 GHPGLPGPPGPPGQCDPSQCAYFASLAARPG 1068 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 97.4 bits (241), Expect = 2e-20 Identities = 50/99 (50%), Positives = 56/99 (56%), Gaps = 10/99 (10%) Query: 246 PGPPGLPGGQGPPGSPGPKGS---PGFPGMPGPPGQPGPRGSMGPMG-------PSPDLS 295 PGPPG PG G PG PGP+G+ PGF G G G PGPRG G MG P D Sbjct: 1251 PGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGD 1310 Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G +GP GP G PG++GS G G PGP G+PG GS Sbjct: 1311 TGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGS 1349 Score = 95.9 bits (237), Expect = 6e-20 Identities = 47/92 (51%), Positives = 55/92 (59%), Gaps = 6/92 (6%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPG---QPGPRGSMGPMGPS--PDLSHIKQGR 301 G PG+PG GPPG+PGP G+ G G GPPG PG G GP GPS P + ++G+ Sbjct: 1186 GHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG-EEGK 1244 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G PG PG G GE G PGP G+ GPPG Sbjct: 1245 EGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG 1276 Score = 95.5 bits (236), Expect = 8e-20 Identities = 50/96 (52%), Positives = 56/96 (58%), Gaps = 4/96 (4%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGP 304 PGPPG+PG GP GSPG G GFPG PGPPG GP G GP G P P + + G RG Sbjct: 716 PGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGE 775 Query: 305 VGPPGAPGRDGSKGER---GAPGPRGSPGPPGSFDF 337 G PG PG G GE+ G PG +G G PG+ F Sbjct: 776 DGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGF 811 Score = 90.9 bits (224), Expect = 2e-18 Identities = 48/99 (48%), Positives = 54/99 (54%), Gaps = 14/99 (14%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGS------------MGPMGPSPDL 294 GP G G QGP G PG GSPG PG PGP G PG +GS +GP GP + Sbjct: 1312 GPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEP 1371 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 ++G G G PG PG G KGERG PG +G GPPG Sbjct: 1372 G--EKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPG 1408 Score = 89.4 bits (220), Expect = 5e-18 Identities = 47/100 (47%), Positives = 53/100 (53%), Gaps = 13/100 (13%) Query: 247 GPPGLPGGQGPPGSPGPKGS------PGFPGMPGPPGQPGPRGSMGPMGP-SPDLSHIKQ 299 GPPG G G G+PGP+G PG G+PG G GP G GP GP P + Sbjct: 1273 GPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 1332 Query: 300 GRRGPVGPPGAPGRDGSKGERGAP------GPRGSPGPPG 333 G G GP G PG+ GSKGE G+P GPRG PG PG Sbjct: 1333 GSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPG 1372 Score = 87.8 bits (216), Expect = 2e-17 Identities = 48/94 (51%), Positives = 50/94 (53%), Gaps = 14/94 (14%) Query: 246 PGPPGLPGGQGPPGSPG------PKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299 PG PGL G QGPPG PG P GSPG PG G PG+PGP G GP G K Sbjct: 704 PGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPG--------KD 755 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP GPPG G G +GE G PG G G G Sbjct: 756 GPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIG 789 Score = 87.4 bits (215), Expect = 2e-17 Identities = 49/102 (48%), Positives = 53/102 (51%), Gaps = 11/102 (10%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 GD L L G PG G QGP G PG KG G G PG G PG G +G GPS Sbjct: 874 GDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPS--- 930 Query: 295 SHIKQGRRGPVGPP---GAPGRDGSKGERGAPGPRGSPGPPG 333 G G VG P G PG+DG +GE+GA G GSPGP G Sbjct: 931 -----GPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVG 967 Score = 87.0 bits (214), Expect = 3e-17 Identities = 57/156 (36%), Positives = 69/156 (44%), Gaps = 50/156 (32%) Query: 229 LGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFP------GMPGPPGQPGPR 282 +G + G+K + LPGPPG G +G G PG G PG P G GPPG PGP Sbjct: 521 IGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPP 580 Query: 283 GSMGPMG----------------------------------PSPDLSHIKQGRR---GPV 305 G +G G P P QG + GP Sbjct: 581 GRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPA 640 Query: 306 GPPGAPG----RDGSKGERGAPGPR---GSPGPPGS 334 GPPG PG ++G KGE+GAPGPR G+PGPPG+ Sbjct: 641 GPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGA 676 Score = 87.0 bits (214), Expect = 3e-17 Identities = 46/93 (49%), Positives = 49/93 (52%), Gaps = 14/93 (15%) Query: 247 GPPGLPG------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300 GPPG+PG GPPG PGP G G PG+PG G PG G GP GP G Sbjct: 702 GPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGP--------PG 753 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 + GP GPPG PG G GERG G G PG G Sbjct: 754 KDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRG 786 Score = 85.5 bits (210), Expect = 8e-17 Identities = 45/89 (50%), Positives = 50/89 (56%), Gaps = 3/89 (3%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI--KQGRRGP 304 GPPGL G +G G GP G PG G+ GPPG PG G GP G SP L G+ GP Sbjct: 687 GPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGP-GGSPGLPGEIGFPGKPGP 745 Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G PG+DG G G PG +G PG G Sbjct: 746 PGPTGPPGKDGPNGPPGPPGTKGEPGERG 774 Score = 85.1 bits (209), Expect = 1e-16 Identities = 46/109 (42%), Positives = 55/109 (50%), Gaps = 9/109 (8%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQG-------PPGSPGPKGSPGFPGMPGPPGQPGPRGSM 285 + GD+ GPPGLPG PG GPKG G PG+PG PG G G + Sbjct: 832 LKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGEL 891 Query: 286 GPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 GP GP+ +G+ G G PGA G G+ G GAPGP G PG G+ Sbjct: 892 GPQGPTGPPG--AKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGA 938 Score = 85.1 bits (209), Expect = 1e-16 Identities = 45/93 (48%), Positives = 51/93 (54%), Gaps = 4/93 (4%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRG 303 +PG PG G +G G GP G PG PG+ GP G G RG+ G +G D H G G Sbjct: 1136 VPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMG 1195 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSP---GPPG 333 P G PG PG DG G G PG +GSP GPPG Sbjct: 1196 PPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPG 1228 Score = 85.1 bits (209), Expect = 1e-16 Identities = 44/93 (47%), Positives = 47/93 (50%), Gaps = 5/93 (5%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG PG G PG GP G PG PG G G GP G G G D G RG + Sbjct: 1499 PGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEM 1558 Query: 306 GPPGAPGRDGSKGER-----GAPGPRGSPGPPG 333 GPPG PG+ G G G PGP+G GP G Sbjct: 1559 GPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAG 1591 Score = 84.3 bits (207), Expect = 2e-16 Identities = 48/110 (43%), Positives = 57/110 (51%), Gaps = 22/110 (20%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGM-------------PGPPGQ---PGPRGSMGPMG 289 PGP G+ G QG G GP G PG PG PGP G PGP G+ GP+G Sbjct: 622 PGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIG 681 Query: 290 PS-----PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 P P L ++ G++G +GPPG PG G +G G PG G PGP GS Sbjct: 682 PEGRDGPPGLQGLR-GKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGS 730 Score = 84.3 bits (207), Expect = 2e-16 Identities = 45/95 (47%), Positives = 50/95 (52%), Gaps = 14/95 (14%) Query: 246 PGPPGLPG------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299 PGPPGLPG +G PG PG +G+ G G GPPG PGP G GP G Q Sbjct: 1119 PGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQG--------SQ 1170 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G RG G G G G G G GP G+PGPPG+ Sbjct: 1171 GERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGA 1205 Score = 84.3 bits (207), Expect = 2e-16 Identities = 43/88 (48%), Positives = 49/88 (55%), Gaps = 5/88 (5%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG PG G +GPPG PG KG PG G+PG PG+PG +G G G D +G G Sbjct: 1356 PGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGD-----KGPPGGK 1410 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG PG G KG G GP+G PG G Sbjct: 1411 GQPGDPGIPGHKGHTGLMGPQGLPGENG 1438 Score = 83.2 bits (204), Expect = 4e-16 Identities = 44/87 (50%), Positives = 50/87 (57%), Gaps = 4/87 (4%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G G G GP G PGPKG G GP G PGP+G G +G P ++G +G +G Sbjct: 481 GEKGEMGVAGPMGLPGPKGDIG---AIGPVGAPGPKGEKGDVGIGP-FGQGEKGEKGSLG 536 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 PG PGRDGSKG RG PG G PG PG Sbjct: 537 LPGPPGRDGSKGMRGEPGELGEPGLPG 563 Score = 82.4 bits (202), Expect = 7e-16 Identities = 44/87 (50%), Positives = 48/87 (55%), Gaps = 2/87 (2%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G PG G QG PG PG +G G G GPPG G RG G MGP P + + G +GP G Sbjct: 660 GAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGP-PGIPGL-LGLQGPPG 717 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 PPG PG G G G PG G PG PG Sbjct: 718 PPGVPGPPGPGGSPGLPGEIGFPGKPG 744 Score = 81.6 bits (200), Expect = 1e-15 Identities = 45/108 (41%), Positives = 53/108 (49%), Gaps = 14/108 (12%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---------PGPRGSM 285 G L PG PG PG GPPG GP G PG PG G PG+ PG RG + Sbjct: 729 GSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEI 788 Query: 286 GPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G + + G +G G PGAPG G +GE+G G +G G PG Sbjct: 789 GEQGLAG-----RPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPG 831 Score = 80.9 bits (198), Expect = 2e-15 Identities = 51/134 (38%), Positives = 57/134 (42%), Gaps = 33/134 (24%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292 I GDK PG PG+PG +G G GP+G PG G GPPG PG G G G SP Sbjct: 1400 IKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESP 1459 Query: 293 DLSHIK------------------------------QGRRGPVGPP---GAPGRDGSKGE 319 + ++ QGR GP GPP G PGR G GE Sbjct: 1460 SMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGE 1519 Query: 320 RGAPGPRGSPGPPG 333 G PG G GP G Sbjct: 1520 PGRPGQGGLEGPSG 1533 Score = 80.5 bits (197), Expect = 3e-15 Identities = 50/130 (38%), Positives = 56/130 (43%), Gaps = 31/130 (23%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGP------------------------KGSPGFP 270 GDK + G G G GPPG PGP +G PG P Sbjct: 1132 GDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVP 1191 Query: 271 GMPGPPGQPGPRGSMGPMG----PSPDLSHIKQGRRGPVGP---PGAPGRDGSKGERGAP 323 G GPPG PGP G+ G G P S K+G GP GP PG PG +G +G G P Sbjct: 1192 GFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKP 1251 Query: 324 GPRGSPGPPG 333 GP G PG G Sbjct: 1252 GPPGEPGKAG 1261 Score = 79.7 bits (195), Expect = 4e-15 Identities = 42/99 (42%), Positives = 51/99 (51%), Gaps = 10/99 (10%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG---------PSPDLS 295 LPG PG PG +G G G KG G PG+ G G+ G G GP G P P + Sbjct: 805 LPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMP 864 Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 +QG +G G PG PG G +G G GP+G GPPG+ Sbjct: 865 G-EQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGA 902 Score = 79.7 bits (195), Expect = 4e-15 Identities = 42/86 (48%), Positives = 47/86 (54%), Gaps = 3/86 (3%) Query: 248 PPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGP 307 P + QG PG PGP G G PG GP G+PG G G GPS + +G RG G Sbjct: 1489 PAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIG--PKGERGAKGD 1546 Query: 308 PGAPGRDGSKGERGAPGPRGSPGPPG 333 PGAPG G +GE G PG G PG PG Sbjct: 1547 PGAPG-VGLRGEMGPPGIPGQPGEPG 1571 Score = 79.3 bits (194), Expect = 6e-15 Identities = 47/97 (48%), Positives = 51/97 (52%), Gaps = 15/97 (15%) Query: 240 ASNTYLPGPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296 A N PG G PG GPPGS PG +G+PG G G G G GS GP+GP Sbjct: 915 AGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGP------ 968 Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 RG G PG PG G KG+ G PG RGSPG PG Sbjct: 969 -----RGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPG 999 Score = 78.6 bits (192), Expect = 1e-14 Identities = 47/100 (47%), Positives = 54/100 (54%), Gaps = 3/100 (3%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPD 293 G+ +A LPGP G G GP G+PGPKG G G+ GP GQ G +G G +G P P Sbjct: 484 GEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGI-GPFGQ-GEKGEKGSLGLPGPP 541 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G RG G G PG G G RG GP G PGPPG Sbjct: 542 GRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPG 581 Score = 78.6 bits (192), Expect = 1e-14 Identities = 44/108 (40%), Positives = 51/108 (47%), Gaps = 19/108 (17%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--------------PSP 292 GPPG G GPPG PG KG PG G G PG+PG RG +G G +P Sbjct: 750 GPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAP 809 Query: 293 DLSHIK-----QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSF 335 ++ QG +G +G PG G G KGE G GP G PG F Sbjct: 810 GFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLF 857 Score = 77.0 bits (188), Expect = 3e-14 Identities = 46/106 (43%), Positives = 51/106 (48%), Gaps = 7/106 (6%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGP--KGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292 G+K A PGP G G G PG PGP KG G PG+ G PG PGP G+ G Sbjct: 952 GEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVR 1011 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAP-----GPRGSPGPPG 333 + G + G GAPG GS G RG P GP G GPPG Sbjct: 1012 GSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPG 1057 Score = 74.3 bits (181), Expect = 2e-13 Identities = 48/124 (38%), Positives = 57/124 (45%), Gaps = 31/124 (25%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGM---------------------PGPPGQPGPRGS 284 PGP G G G PG+PG +G PG PG+ PGPPG PG G Sbjct: 1071 PGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGF 1130 Query: 285 MGPMG----PSPDLSHIKQGRRGPVG---PPGAPGRDGSKGERGAPGP---RGSPGPPGS 334 G G P + + K+G GP G PPG G GS+GERGA G +G G PG Sbjct: 1131 KGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGV 1190 Query: 335 FDFL 338 F+ Sbjct: 1191 PGFM 1194 Score = 73.6 bits (179), Expect = 3e-13 Identities = 54/141 (38%), Positives = 59/141 (41%), Gaps = 38/141 (26%) Query: 245 LPGPPGL-----PGGQGPPGSPGP--------------------------KGSPGFPGMP 273 LPGPPG PG +G PG PGP +G+PG PG P Sbjct: 977 LPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSP 1036 Query: 274 GPPGQPGPRGSMGPMGPS-PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPP 332 G G PG G GP GPS P G RG G PG G G G G PG RG PG P Sbjct: 1037 GSRGDPG-IGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKP 1095 Query: 333 GSFDFLL-----LMLADIRND 348 G L L+ D+ ND Sbjct: 1096 GLSSLLSPGDINLLAKDVCND 1116 Score = 73.6 bits (179), Expect = 3e-13 Identities = 41/90 (45%), Positives = 47/90 (52%), Gaps = 8/90 (8%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGPS 291 G+K + +PG PG PG +G G PG KG G PG G PG PG +G G MGP Sbjct: 1372 GEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQ 1431 Query: 292 PDLSHIKQGRRGPVGPPGAPGRDGSKGERG 321 G GPVGPPG PG+ G G RG Sbjct: 1432 G-----LPGENGPVGPPGPPGQPGFPGLRG 1456 Score = 71.2 bits (173), Expect = 2e-12 Identities = 45/108 (41%), Positives = 55/108 (50%), Gaps = 11/108 (10%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPG--QPGPRGSMG------ 286 GDK + LPG PG G G G+PG G G PG PG PG + Sbjct: 1057 GDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCND 1116 Query: 287 -PMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P GP P L + G +G G PG PGR+G++G++G GP G PGPPG Sbjct: 1117 CPPGP-PGLPGL-PGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPG 1162 Score = 67.0 bits (162), Expect = 3e-11 Identities = 42/108 (38%), Positives = 46/108 (42%), Gaps = 20/108 (18%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG G PG +G PG G +G G G G PG GPRG G G K G G Sbjct: 933 PGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLR 992 Query: 306 GPPGAPGRDGS--------------------KGERGAPGPRGSPGPPG 333 G PG PG G+ KG+RGAPG GSPG G Sbjct: 993 GSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRG 1040 Score = 63.2 bits (152), Expect = 4e-10 Identities = 37/92 (40%), Positives = 43/92 (46%), Gaps = 23/92 (25%) Query: 247 GPPGLPGGQGPPGSPGP--KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 GP G G +G PG+PG +G G PG+PG PG+PG + K G Sbjct: 1536 GPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG---------------YAKDGL--- 1577 Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPGSFD 336 PG PG G G G PG G PGPPG D Sbjct: 1578 ---PGIPGPQGETGPAGHPGLPGPPGPPGQCD 1606 Score = 50.8 bits (120), Expect = 2e-06 Identities = 24/41 (58%), Positives = 24/41 (58%), Gaps = 5/41 (12%) Query: 246 PGPPG-----LPGGQGPPGSPGPKGSPGFPGMPGPPGQPGP 281 PG PG LPG GP G GP G PG PG PGPPGQ P Sbjct: 1567 PGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDP 1607 Score = 50.4 bits (119), Expect = 3e-06 Identities = 29/62 (46%), Positives = 31/62 (50%), Gaps = 16/62 (25%) Query: 246 PGPPG--LPGGQGPPGSPGPKGSPGF-----PGMPGP---------PGQPGPRGSMGPMG 289 PG PG L G GPPG PG G PG+ PG+PGP PG PGP G G Sbjct: 1547 PGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCD 1606 Query: 290 PS 291 PS Sbjct: 1607 PS 1608 Score = 50.1 bits (118), Expect = 4e-06 Identities = 24/45 (53%), Positives = 26/45 (57%), Gaps = 2/45 (4%) Query: 245 LPGPPGLPG--GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGP 287 +PG PG PG G PG PGP+G G G PG PG PGP G P Sbjct: 1563 IPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDP 1607 Score = 31.6 bits (70), Expect = 1.3 Identities = 14/31 (45%), Positives = 15/31 (48%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPG 277 G PGLPG GPPG P F + PG Sbjct: 1591 GHPGLPGPPGPPGQCDPSQCAYFASLAARPG 1621 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 97.1 bits (240), Expect = 3e-20 Identities = 48/88 (54%), Positives = 51/88 (57%), Gaps = 11/88 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG GLPG QGP G PGPKG PG PG G PG PG RG +G QG+ GP Sbjct: 787 PGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVG-----------FQGKTGPP 835 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPG G G+ GE G G RG PGPPG Sbjct: 836 GPPGVVGPQGAAGETGPMGERGHPGPPG 863 Score = 94.0 bits (232), Expect = 2e-19 Identities = 48/92 (52%), Positives = 52/92 (56%), Gaps = 14/92 (15%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 PG PG PG +GP G GPKG+PG FPG PGPPG+ GPRG G +G R Sbjct: 1159 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA-----------KGDR 1207 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G G PG PG G GE G PGP G GP GS Sbjct: 1208 GEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1239 Score = 94.0 bits (232), Expect = 2e-19 Identities = 51/106 (48%), Positives = 55/106 (51%), Gaps = 17/106 (16%) Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMGP 287 TGD N PGP G PG GPPG GP KG G G PG PG PGP G GP Sbjct: 1171 TGDDGPKGN---PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGP 1227 Query: 288 MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G+RGP G PG+ GR G KG +G PG G+PG G Sbjct: 1228 PGP--------LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1265 Score = 93.2 bits (230), Expect = 4e-19 Identities = 47/99 (47%), Positives = 54/99 (54%), Gaps = 11/99 (11%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 G+ T PGPPG+ G QG G GP G G PG PGPPG+ G G+ G Sbjct: 824 GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG-------- 875 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 K+G +G GPPGAPG+DG G RG PG RG PG G Sbjct: 876 ---KEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 911 Score = 90.5 bits (223), Expect = 2e-18 Identities = 56/127 (44%), Positives = 61/127 (48%), Gaps = 28/127 (22%) Query: 235 GDKVLASNTYLPGPPGL---------PGGQGPPGSPGPKGSPGFPGMPGPPGQ------- 278 G K T PGPPGL PG G PG GPKGS GFPG PG G+ Sbjct: 686 GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS 745 Query: 279 --PGPRGSMGPMGP----SPDLSHIKQGRR------GPVGPPGAPGRDGSKGERGAPGPR 326 GPRG GP GP P + K G + GP GPPG G G +G G PGP+ Sbjct: 746 GKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK 805 Query: 327 GSPGPPG 333 G PGPPG Sbjct: 806 GPPGPPG 812 Score = 89.4 bits (220), Expect = 5e-18 Identities = 49/101 (48%), Positives = 55/101 (54%), Gaps = 13/101 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR---GSMGPMGPS-PDLSHIKQGR 301 PGP G PG +G GS GP G PG PG GPPG G + G GP+GP+ D G Sbjct: 925 PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL 984 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGS---------PGPPG 333 GP GPPG G DG KGE G PG +G+ PGPPG Sbjct: 985 PGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1025 Score = 88.6 bits (218), Expect = 9e-18 Identities = 44/87 (50%), Positives = 47/87 (54%), Gaps = 8/87 (9%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GP GLPG GP G GPKG PG PG PG G GP+G G +GP QG GP G Sbjct: 512 GPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGP--------QGEPGPPG 563 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG G G +GA GP G GP G Sbjct: 564 QQGTPGTQGLPGPQGAIGPHGEKGPQG 590 Score = 88.2 bits (217), Expect = 1e-17 Identities = 45/88 (51%), Positives = 53/88 (60%), Gaps = 1/88 (1%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-PDLSHIKQGRRGPV 305 GPPG PG QGPPG+ G KG PG G GP G+ G +G +G GP+ P + G +G V Sbjct: 944 GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1003 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG G G+KGE G PGP G GP G Sbjct: 1004 GDPGQKGTKGNKGEHGPPGPPGPIGPVG 1031 Score = 86.3 bits (212), Expect = 5e-17 Identities = 42/88 (47%), Positives = 49/88 (55%), Gaps = 1/88 (1%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305 G G G +G PG PG KG GF G+PG PG+ G RG G G P P ++G G + Sbjct: 452 GRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI 511 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G PG G +G G GP G PGPPG Sbjct: 512 GPRGLPGESGPRGLLGPKGPPGIPGPPG 539 Score = 86.3 bits (212), Expect = 5e-17 Identities = 46/96 (47%), Positives = 55/96 (57%), Gaps = 7/96 (7%) Query: 245 LPGPPGL---PGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMG-PSPDLSHI 297 +PGPPG+ G QGP GS GP+G PG PG G PG PGP+G++GP G P Sbjct: 534 IPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 593 Query: 298 KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G GPPG PG++G G +G GP G GP G Sbjct: 594 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLG 629 Score = 85.9 bits (211), Expect = 6e-17 Identities = 44/89 (49%), Positives = 49/89 (55%), Gaps = 2/89 (2%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG PG PG +G G GPKGS G G PGPPGQ G G+ G GP + G +GP Sbjct: 532 PGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG--PHGEKGPQ 589 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G PG PG GS G G PG G PG G+ Sbjct: 590 GKPGLPGMPGSDGPPGHPGKEGPPGTKGN 618 Score = 85.9 bits (211), Expect = 6e-17 Identities = 48/111 (43%), Positives = 56/111 (50%), Gaps = 4/111 (3%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282 P +LG G+K + PG G PG +GP G G KG G PG PGPPG GP Sbjct: 1114 PGGVGNLGP--PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1171 Query: 283 GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP G + G GP G G G+DG+KG+RG G G PG PG Sbjct: 1172 GDDGPKGNPGPVGF--PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPG 1220 Score = 85.5 bits (210), Expect = 8e-17 Identities = 50/110 (45%), Positives = 57/110 (51%), Gaps = 27/110 (24%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---------PGPRGS------------M 285 GPPGLPG +G G+ G KG PG G+ GPPG+ PGP+GS Sbjct: 1307 GPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGAS 1366 Query: 286 GPMGPS--PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP+GP P L G GP G GA G G KGE+G GP G PGPPG Sbjct: 1367 GPIGPGGPPGL----PGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1412 Score = 85.1 bits (209), Expect = 1e-16 Identities = 47/110 (42%), Positives = 53/110 (48%), Gaps = 22/110 (20%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSMGPMGPSPDLSHIKQ 299 PG PG+PG GPPG PG +G PG G GP G PGPRG G G H + Sbjct: 592 PGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGE 651 Query: 300 ----------------GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G RG VG PG+ G DG +G +G GP G PGPPG Sbjct: 652 KGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPG 701 Score = 85.1 bits (209), Expect = 1e-16 Identities = 46/100 (46%), Positives = 50/100 (50%), Gaps = 1/100 (1%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 GDK + G G G GPPG PGP G G PG G G+PG RG G G D Sbjct: 998 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1057 Query: 295 -SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 + G GP+G G PG G KGE G GP G PGPPG Sbjct: 1058 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPG 1097 Score = 84.7 bits (208), Expect = 1e-16 Identities = 50/131 (38%), Positives = 58/131 (44%), Gaps = 43/131 (32%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG---PRGSMGPMGPSPDLSHI------ 297 GPPG PG G PG PG +G GF G GPPG PG P+G+ G GP + H Sbjct: 806 GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPP 865 Query: 298 ----------KQGRRGPVGPPGAPGRDGSKGERG------------------------AP 323 K+G +G GPPGAPG+DG G RG P Sbjct: 866 GEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 925 Query: 324 GPRGSPGPPGS 334 GP GSPG G+ Sbjct: 926 GPAGSPGERGA 936 Score = 84.3 bits (207), Expect = 2e-16 Identities = 46/103 (44%), Positives = 58/103 (56%), Gaps = 15/103 (14%) Query: 245 LPGPPGLPGGQG------PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PDLSH 296 +PG PG+ G +G PG G +G G G+PGPPG+ G RG G +GP P S Sbjct: 462 MPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESG 521 Query: 297 IKQGRRGPVGPPGAP------GRDGSKGERGAPGPRGSPGPPG 333 +G GP GPPG P G DG +G +G+ GP+G PGPPG Sbjct: 522 -PRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPG 563 Score = 84.0 bits (206), Expect = 2e-16 Identities = 45/100 (45%), Positives = 50/100 (50%), Gaps = 20/100 (20%) Query: 246 PGPPGLPGGQGPP---------GSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296 PGPPG PG GP G PG G PG G GP G PGP GS G G + Sbjct: 883 PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAA----- 937 Query: 297 IKQGRRGPVGPPGAPGRD---GSKGERGAPGPRGSPGPPG 333 G GP+GPPG PG G+ GE+G PG +G GP G Sbjct: 938 ---GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTG 974 Score = 83.6 bits (205), Expect = 3e-16 Identities = 43/87 (49%), Positives = 45/87 (51%), Gaps = 5/87 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GPPG G GPPG G G G PG+ G PG GPRG G G S + G GP G Sbjct: 1112 GPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG-----QPGEPGPPG 1166 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 P G G DG KG G G G PGPPG Sbjct: 1167 PKGPTGDDGPKGNPGPVGFPGDPGPPG 1193 Score = 83.6 bits (205), Expect = 3e-16 Identities = 44/98 (44%), Positives = 51/98 (52%), Gaps = 10/98 (10%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLSHIK----- 298 PG G G GP G PGP G G PG G G+PG G GP GP P L ++ Sbjct: 1261 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA 1320 Query: 299 ---QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G G +G G PG G KG+RG PGP+GSPG G Sbjct: 1321 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKG 1358 Score = 83.2 bits (204), Expect = 4e-16 Identities = 44/92 (47%), Positives = 52/92 (56%), Gaps = 4/92 (4%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPP---GQPGPRGSMGPMG-PSPDLSHIKQGR 301 PGPPG G GP G+ GP+G PG G GPP G+PG GS G G P ++G Sbjct: 1093 PGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGE 1152 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G G PG PG G KG G GP+G+PGP G Sbjct: 1153 KGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG 1184 Score = 82.4 bits (202), Expect = 7e-16 Identities = 44/87 (50%), Positives = 45/87 (51%), Gaps = 11/87 (12%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GPPG G QG PG G KG G G GPPG PGPRG GP G GP G Sbjct: 1064 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGP-----------NGADGPQG 1112 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 PPG G G GE+G PG GSPG G Sbjct: 1113 PPGGVGNLGPPGEKGEPGESGSPGIQG 1139 Score = 81.3 bits (199), Expect = 1e-15 Identities = 44/99 (44%), Positives = 52/99 (52%), Gaps = 10/99 (10%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----PSPDLSHIKQGR 301 PGPPG PG QG PG+ G +G+ G PG PG PG+ GP G G G P +G Sbjct: 859 PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 918 Query: 302 RGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPGS 334 GP GPPG G G +G G+ GP G GPPG+ Sbjct: 919 EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGA 957 Score = 81.3 bits (199), Expect = 1e-15 Identities = 48/118 (40%), Positives = 53/118 (44%), Gaps = 19/118 (16%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----- 289 G K N GPPG PG GP G PG G+ G PG GP G G +G G G Sbjct: 1007 GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP 1066 Query: 290 --------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSP------GPPG 333 P P + G GP+GPPG PG G G GA GP+G P GPPG Sbjct: 1067 GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1124 Score = 80.1 bits (196), Expect = 3e-15 Identities = 46/94 (48%), Positives = 51/94 (54%), Gaps = 13/94 (13%) Query: 247 GPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQ 299 GPPG G +GP GSPG KG+ G PG G PG+ GP G GP G P PD Sbjct: 1226 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPD------ 1279 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G RG G G GR G+ G+ G PGP G PG PG Sbjct: 1280 GLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1313 Score = 79.7 bits (195), Expect = 4e-15 Identities = 45/95 (47%), Positives = 48/95 (50%), Gaps = 8/95 (8%) Query: 246 PGPPGLPGGQG---PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 PG GLPG QG P G GP+G PG PGMPG G PG G GP G + QG Sbjct: 568 PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN-----QGPS 622 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 GP GP G PG G KG G G +G G G F Sbjct: 623 GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 657 Score = 79.3 bits (194), Expect = 6e-15 Identities = 44/101 (43%), Positives = 52/101 (51%), Gaps = 23/101 (22%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP------------PGQPGPRGSMGPMGPSP 292 LPGPPG G +G G GP+G PG GP PG PG RG GP GP Sbjct: 495 LPGPPGEDGERGDDGEIGPRG---LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP-- 549 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G GP G PG PG+ G+ G +G PGP+G+ GP G Sbjct: 550 ------KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHG 584 Score = 76.3 bits (186), Expect = 5e-14 Identities = 46/112 (41%), Positives = 54/112 (48%), Gaps = 20/112 (17%) Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGM------PGPPGQPGPRGSMGP 287 +G+K + GP G G GP G GP+G+ G G GP G PG RG GP Sbjct: 736 SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 795 Query: 288 MGPSPDLSHIKQGRRGPVGPPGAPGRD------GSKGERGAPGPRGSPGPPG 333 GP+ G GP GPPG PG+D G +GE G G G PGPPG Sbjct: 796 QGPN--------GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPG 839 Score = 76.3 bits (186), Expect = 5e-14 Identities = 45/111 (40%), Positives = 50/111 (45%), Gaps = 10/111 (9%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289 + G + A T G G PG GPPG PG G G G PGPPG PG G G G Sbjct: 840 VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRG 899 Query: 290 -------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P +G GP GPPG G G +G G+ GP G PG PG Sbjct: 900 FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 950 Score = 76.3 bits (186), Expect = 5e-14 Identities = 42/101 (41%), Positives = 49/101 (48%), Gaps = 13/101 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGPSPDLSHI----- 297 PGP GL G GP G G G G G PGPPG GP G+ GP GP + ++ Sbjct: 1066 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGE 1125 Query: 298 -----KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 + G G G PG G G +GE+G G G PGPPG Sbjct: 1126 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG 1166 Score = 75.9 bits (185), Expect = 6e-14 Identities = 46/126 (36%), Positives = 56/126 (44%), Gaps = 39/126 (30%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGS--------------MGPM-- 288 L GPPG+ G GP G PG +G PG G+PG G PGP G+ GP+ Sbjct: 323 LIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVA 382 Query: 289 ------------------GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS-- 328 GP + + GR GP+G PG+PG G G+ G GPRG Sbjct: 383 AQEAQAQAILQQARLALRGPPGPMGY--TGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 440 Query: 329 -PGPPG 333 GPPG Sbjct: 441 LTGPPG 446 Score = 74.7 bits (182), Expect = 1e-13 Identities = 42/93 (45%), Positives = 47/93 (50%), Gaps = 14/93 (15%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGP------PGQPGPRGSMGPMGPSPDLSHIKQG 300 GP G G QGP G PGP G PG G G PGQ G +G+ G GP G Sbjct: 971 GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP--------PG 1022 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP+GP G PG G+ GE GA GP+G G G Sbjct: 1023 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG 1055 Score = 74.7 bits (182), Expect = 1e-13 Identities = 42/93 (45%), Positives = 49/93 (52%), Gaps = 4/93 (4%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLSHI--KQG 300 LPGP G PG G G G G PG G G G+ GP G GP+GP P + + G Sbjct: 984 LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPG 1043 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 RGP G GA G +G++G G PGP G G PG Sbjct: 1044 ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPG 1076 Score = 74.3 bits (181), Expect = 2e-13 Identities = 42/90 (46%), Positives = 49/90 (54%), Gaps = 5/90 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G G+PG +G G GPKG G G PGPPG G +G +G G P +QG +G +G Sbjct: 671 GEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG-LPGYPG-RQGPKGSLG 728 Query: 307 PPGAPGRDGSKGER---GAPGPRGSPGPPG 333 PG PG G KG R G GPRG GP G Sbjct: 729 FPGFPGASGEKGARGLSGKSGPRGERGPTG 758 Score = 73.6 bits (179), Expect = 3e-13 Identities = 46/107 (42%), Positives = 47/107 (43%), Gaps = 23/107 (21%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 L GPPG G G PG G GSPG G G G GPRG G GP K GRRG Sbjct: 399 LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPG-----KAGRRGR 453 Query: 305 VGPPGA------------------PGRDGSKGERGAPGPRGSPGPPG 333 G GA PG G KG RG G +G PGPPG Sbjct: 454 AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 500 Score = 72.0 bits (175), Expect = 9e-13 Identities = 45/131 (34%), Positives = 58/131 (44%), Gaps = 27/131 (20%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 LPGP G PG +G G PG G G G PG PG GP+G+ G GP +G +G Sbjct: 1347 LPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGG-----PKGEKGV 1401 Query: 305 VGPPGAPGRDG-----------SKGERGAPGPR-----------GSPGPPGSFDFLLLML 342 GPPG PG G K R G R G+PG PG + + L Sbjct: 1402 QGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSL 1461 Query: 343 ADIRNDITELQ 353 +R +I +++ Sbjct: 1462 DSLREEIEQMR 1472 Score = 70.9 bits (172), Expect = 2e-12 Identities = 41/105 (39%), Positives = 52/105 (49%), Gaps = 1/105 (0%) Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG- 289 K + G + L + G G PG +G G G +G G PG G G GP+G GP G Sbjct: 637 KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 696 Query: 290 PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 P P ++G+ G G PG PGR G KG G PG G+ G G+ Sbjct: 697 PGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGA 741 Score = 67.0 bits (162), Expect = 3e-11 Identities = 41/91 (45%), Positives = 44/91 (48%), Gaps = 15/91 (16%) Query: 248 PPGLPGGQGPPGSPGPKGSPGF--PGM--PGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303 PP GP G G KG P PGM GPPG GP G +GP G QG G Sbjct: 283 PPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGI--------QGNPG 334 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 PVG PG G G G PG G+PGPPG+ Sbjct: 335 PVGDPG---ERGPPGRAGLPGSDGAPGPPGT 362 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 97.1 bits (240), Expect = 3e-20 Identities = 48/88 (54%), Positives = 51/88 (57%), Gaps = 11/88 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG GLPG QGP G PGPKG PG PG G PG PG RG +G QG+ GP Sbjct: 766 PGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVG-----------FQGKTGPP 814 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPG G G+ GE G G RG PGPPG Sbjct: 815 GPPGVVGPQGAAGETGPMGERGHPGPPG 842 Score = 94.0 bits (232), Expect = 2e-19 Identities = 48/92 (52%), Positives = 52/92 (56%), Gaps = 14/92 (15%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 PG PG PG +GP G GPKG+PG FPG PGPPG+ GPRG G +G R Sbjct: 1138 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA-----------KGDR 1186 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G G PG PG G GE G PGP G GP GS Sbjct: 1187 GEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1218 Score = 94.0 bits (232), Expect = 2e-19 Identities = 51/106 (48%), Positives = 55/106 (51%), Gaps = 17/106 (16%) Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMGP 287 TGD N PGP G PG GPPG GP KG G G PG PG PGP G GP Sbjct: 1150 TGDDGPKGN---PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGP 1206 Query: 288 MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G+RGP G PG+ GR G KG +G PG G+PG G Sbjct: 1207 PGP--------LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1244 Score = 93.2 bits (230), Expect = 4e-19 Identities = 47/99 (47%), Positives = 54/99 (54%), Gaps = 11/99 (11%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 G+ T PGPPG+ G QG G GP G G PG PGPPG+ G G+ G Sbjct: 803 GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG-------- 854 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 K+G +G GPPGAPG+DG G RG PG RG PG G Sbjct: 855 ---KEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 890 Score = 90.5 bits (223), Expect = 2e-18 Identities = 56/127 (44%), Positives = 61/127 (48%), Gaps = 28/127 (22%) Query: 235 GDKVLASNTYLPGPPGL---------PGGQGPPGSPGPKGSPGFPGMPGPPGQ------- 278 G K T PGPPGL PG G PG GPKGS GFPG PG G+ Sbjct: 665 GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS 724 Query: 279 --PGPRGSMGPMGP----SPDLSHIKQGRR------GPVGPPGAPGRDGSKGERGAPGPR 326 GPRG GP GP P + K G + GP GPPG G G +G G PGP+ Sbjct: 725 GKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK 784 Query: 327 GSPGPPG 333 G PGPPG Sbjct: 785 GPPGPPG 791 Score = 89.4 bits (220), Expect = 5e-18 Identities = 49/101 (48%), Positives = 55/101 (54%), Gaps = 13/101 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR---GSMGPMGPS-PDLSHIKQGR 301 PGP G PG +G GS GP G PG PG GPPG G + G GP+GP+ D G Sbjct: 904 PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL 963 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGS---------PGPPG 333 GP GPPG G DG KGE G PG +G+ PGPPG Sbjct: 964 PGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1004 Score = 88.6 bits (218), Expect = 9e-18 Identities = 44/87 (50%), Positives = 47/87 (54%), Gaps = 8/87 (9%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GP GLPG GP G GPKG PG PG PG G GP+G G +GP QG GP G Sbjct: 491 GPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGP--------QGEPGPPG 542 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG G G +GA GP G GP G Sbjct: 543 QQGTPGTQGLPGPQGAIGPHGEKGPQG 569 Score = 88.2 bits (217), Expect = 1e-17 Identities = 45/88 (51%), Positives = 53/88 (60%), Gaps = 1/88 (1%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-PDLSHIKQGRRGPV 305 GPPG PG QGPPG+ G KG PG G GP G+ G +G +G GP+ P + G +G V Sbjct: 923 GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 982 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG G G+KGE G PGP G GP G Sbjct: 983 GDPGQKGTKGNKGEHGPPGPPGPIGPVG 1010 Score = 86.3 bits (212), Expect = 5e-17 Identities = 42/88 (47%), Positives = 49/88 (55%), Gaps = 1/88 (1%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305 G G G +G PG PG KG GF G+PG PG+ G RG G G P P ++G G + Sbjct: 431 GRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI 490 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G PG G +G G GP G PGPPG Sbjct: 491 GPRGLPGESGPRGLLGPKGPPGIPGPPG 518 Score = 86.3 bits (212), Expect = 5e-17 Identities = 46/96 (47%), Positives = 55/96 (57%), Gaps = 7/96 (7%) Query: 245 LPGPPGL---PGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMG-PSPDLSHI 297 +PGPPG+ G QGP GS GP+G PG PG G PG PGP+G++GP G P Sbjct: 513 IPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 572 Query: 298 KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G GPPG PG++G G +G GP G GP G Sbjct: 573 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLG 608 Score = 85.9 bits (211), Expect = 6e-17 Identities = 44/89 (49%), Positives = 49/89 (55%), Gaps = 2/89 (2%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG PG PG +G G GPKGS G G PGPPGQ G G+ G GP + G +GP Sbjct: 511 PGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG--PHGEKGPQ 568 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G PG PG GS G G PG G PG G+ Sbjct: 569 GKPGLPGMPGSDGPPGHPGKEGPPGTKGN 597 Score = 85.9 bits (211), Expect = 6e-17 Identities = 48/111 (43%), Positives = 56/111 (50%), Gaps = 4/111 (3%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282 P +LG G+K + PG G PG +GP G G KG G PG PGPPG GP Sbjct: 1093 PGGVGNLGP--PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1150 Query: 283 GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP G + G GP G G G+DG+KG+RG G G PG PG Sbjct: 1151 GDDGPKGNPGPVGF--PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPG 1199 Score = 85.5 bits (210), Expect = 8e-17 Identities = 50/110 (45%), Positives = 57/110 (51%), Gaps = 27/110 (24%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---------PGPRGS------------M 285 GPPGLPG +G G+ G KG PG G+ GPPG+ PGP+GS Sbjct: 1286 GPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGAS 1345 Query: 286 GPMGPS--PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP+GP P L G GP G GA G G KGE+G GP G PGPPG Sbjct: 1346 GPIGPGGPPGL----PGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1391 Score = 85.1 bits (209), Expect = 1e-16 Identities = 47/110 (42%), Positives = 53/110 (48%), Gaps = 22/110 (20%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSMGPMGPSPDLSHIKQ 299 PG PG+PG GPPG PG +G PG G GP G PGPRG G G H + Sbjct: 571 PGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGE 630 Query: 300 ----------------GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G RG VG PG+ G DG +G +G GP G PGPPG Sbjct: 631 KGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPG 680 Score = 85.1 bits (209), Expect = 1e-16 Identities = 46/100 (46%), Positives = 50/100 (50%), Gaps = 1/100 (1%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 GDK + G G G GPPG PGP G G PG G G+PG RG G G D Sbjct: 977 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1036 Query: 295 -SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 + G GP+G G PG G KGE G GP G PGPPG Sbjct: 1037 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPG 1076 Score = 84.7 bits (208), Expect = 1e-16 Identities = 50/131 (38%), Positives = 58/131 (44%), Gaps = 43/131 (32%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG---PRGSMGPMGPSPDLSHI------ 297 GPPG PG G PG PG +G GF G GPPG PG P+G+ G GP + H Sbjct: 785 GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPP 844 Query: 298 ----------KQGRRGPVGPPGAPGRDGSKGERG------------------------AP 323 K+G +G GPPGAPG+DG G RG P Sbjct: 845 GEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 904 Query: 324 GPRGSPGPPGS 334 GP GSPG G+ Sbjct: 905 GPAGSPGERGA 915 Score = 84.3 bits (207), Expect = 2e-16 Identities = 46/103 (44%), Positives = 58/103 (56%), Gaps = 15/103 (14%) Query: 245 LPGPPGLPGGQG------PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PDLSH 296 +PG PG+ G +G PG G +G G G+PGPPG+ G RG G +GP P S Sbjct: 441 MPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESG 500 Query: 297 IKQGRRGPVGPPGAP------GRDGSKGERGAPGPRGSPGPPG 333 +G GP GPPG P G DG +G +G+ GP+G PGPPG Sbjct: 501 -PRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPG 542 Score = 84.0 bits (206), Expect = 2e-16 Identities = 45/100 (45%), Positives = 50/100 (50%), Gaps = 20/100 (20%) Query: 246 PGPPGLPGGQGPP---------GSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296 PGPPG PG GP G PG G PG G GP G PGP GS G G + Sbjct: 862 PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAA----- 916 Query: 297 IKQGRRGPVGPPGAPGRD---GSKGERGAPGPRGSPGPPG 333 G GP+GPPG PG G+ GE+G PG +G GP G Sbjct: 917 ---GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTG 953 Score = 83.6 bits (205), Expect = 3e-16 Identities = 43/87 (49%), Positives = 45/87 (51%), Gaps = 5/87 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GPPG G GPPG G G G PG+ G PG GPRG G G S + G GP G Sbjct: 1091 GPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG-----QPGEPGPPG 1145 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 P G G DG KG G G G PGPPG Sbjct: 1146 PKGPTGDDGPKGNPGPVGFPGDPGPPG 1172 Score = 83.6 bits (205), Expect = 3e-16 Identities = 44/98 (44%), Positives = 51/98 (52%), Gaps = 10/98 (10%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLSHIK----- 298 PG G G GP G PGP G G PG G G+PG G GP GP P L ++ Sbjct: 1240 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA 1299 Query: 299 ---QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G G +G G PG G KG+RG PGP+GSPG G Sbjct: 1300 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKG 1337 Score = 83.2 bits (204), Expect = 4e-16 Identities = 44/92 (47%), Positives = 52/92 (56%), Gaps = 4/92 (4%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPP---GQPGPRGSMGPMG-PSPDLSHIKQGR 301 PGPPG G GP G+ GP+G PG G GPP G+PG GS G G P ++G Sbjct: 1072 PGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGE 1131 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G G PG PG G KG G GP+G+PGP G Sbjct: 1132 KGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG 1163 Score = 82.4 bits (202), Expect = 7e-16 Identities = 44/87 (50%), Positives = 45/87 (51%), Gaps = 11/87 (12%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GPPG G QG PG G KG G G GPPG PGPRG GP G GP G Sbjct: 1043 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGP-----------NGADGPQG 1091 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 PPG G G GE+G PG GSPG G Sbjct: 1092 PPGGVGNLGPPGEKGEPGESGSPGIQG 1118 Score = 81.3 bits (199), Expect = 1e-15 Identities = 44/99 (44%), Positives = 52/99 (52%), Gaps = 10/99 (10%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----PSPDLSHIKQGR 301 PGPPG PG QG PG+ G +G+ G PG PG PG+ GP G G G P +G Sbjct: 838 PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 897 Query: 302 RGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPGS 334 GP GPPG G G +G G+ GP G GPPG+ Sbjct: 898 EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGA 936 Score = 81.3 bits (199), Expect = 1e-15 Identities = 48/118 (40%), Positives = 53/118 (44%), Gaps = 19/118 (16%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----- 289 G K N GPPG PG GP G PG G+ G PG GP G G +G G G Sbjct: 986 GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP 1045 Query: 290 --------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSP------GPPG 333 P P + G GP+GPPG PG G G GA GP+G P GPPG Sbjct: 1046 GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1103 Score = 80.1 bits (196), Expect = 3e-15 Identities = 46/94 (48%), Positives = 51/94 (54%), Gaps = 13/94 (13%) Query: 247 GPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQ 299 GPPG G +GP GSPG KG+ G PG G PG+ GP G GP G P PD Sbjct: 1205 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPD------ 1258 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G RG G G GR G+ G+ G PGP G PG PG Sbjct: 1259 GLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1292 Score = 79.7 bits (195), Expect = 4e-15 Identities = 45/95 (47%), Positives = 48/95 (50%), Gaps = 8/95 (8%) Query: 246 PGPPGLPGGQG---PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 PG GLPG QG P G GP+G PG PGMPG G PG G GP G + QG Sbjct: 547 PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN-----QGPS 601 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 GP GP G PG G KG G G +G G G F Sbjct: 602 GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 636 Score = 79.3 bits (194), Expect = 6e-15 Identities = 44/101 (43%), Positives = 52/101 (51%), Gaps = 23/101 (22%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP------------PGQPGPRGSMGPMGPSP 292 LPGPPG G +G G GP+G PG GP PG PG RG GP GP Sbjct: 474 LPGPPGEDGERGDDGEIGPRG---LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP-- 528 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G GP G PG PG+ G+ G +G PGP+G+ GP G Sbjct: 529 ------KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHG 563 Score = 76.3 bits (186), Expect = 5e-14 Identities = 46/112 (41%), Positives = 54/112 (48%), Gaps = 20/112 (17%) Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGM------PGPPGQPGPRGSMGP 287 +G+K + GP G G GP G GP+G+ G G GP G PG RG GP Sbjct: 715 SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 774 Query: 288 MGPSPDLSHIKQGRRGPVGPPGAPGRD------GSKGERGAPGPRGSPGPPG 333 GP+ G GP GPPG PG+D G +GE G G G PGPPG Sbjct: 775 QGPN--------GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPG 818 Score = 76.3 bits (186), Expect = 5e-14 Identities = 45/111 (40%), Positives = 50/111 (45%), Gaps = 10/111 (9%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289 + G + A T G G PG GPPG PG G G G PGPPG PG G G G Sbjct: 819 VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRG 878 Query: 290 -------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P +G GP GPPG G G +G G+ GP G PG PG Sbjct: 879 FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 929 Score = 76.3 bits (186), Expect = 5e-14 Identities = 42/101 (41%), Positives = 49/101 (48%), Gaps = 13/101 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGPSPDLSHI----- 297 PGP GL G GP G G G G G PGPPG GP G+ GP GP + ++ Sbjct: 1045 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGE 1104 Query: 298 -----KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 + G G G PG G G +GE+G G G PGPPG Sbjct: 1105 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG 1145 Score = 75.9 bits (185), Expect = 6e-14 Identities = 46/126 (36%), Positives = 56/126 (44%), Gaps = 39/126 (30%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGS--------------MGPM-- 288 L GPPG+ G GP G PG +G PG G+PG G PGP G+ GP+ Sbjct: 302 LIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVA 361 Query: 289 ------------------GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS-- 328 GP + + GR GP+G PG+PG G G+ G GPRG Sbjct: 362 AQEAQAQAILQQARLALRGPPGPMGY--TGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 419 Query: 329 -PGPPG 333 GPPG Sbjct: 420 LTGPPG 425 Score = 74.7 bits (182), Expect = 1e-13 Identities = 42/93 (45%), Positives = 47/93 (50%), Gaps = 14/93 (15%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGP------PGQPGPRGSMGPMGPSPDLSHIKQG 300 GP G G QGP G PGP G PG G G PGQ G +G+ G GP G Sbjct: 950 GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP--------PG 1001 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP+GP G PG G+ GE GA GP+G G G Sbjct: 1002 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG 1034 Score = 74.7 bits (182), Expect = 1e-13 Identities = 42/93 (45%), Positives = 49/93 (52%), Gaps = 4/93 (4%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLSHI--KQG 300 LPGP G PG G G G G PG G G G+ GP G GP+GP P + + G Sbjct: 963 LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPG 1022 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 RGP G GA G +G++G G PGP G G PG Sbjct: 1023 ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPG 1055 Score = 74.3 bits (181), Expect = 2e-13 Identities = 42/90 (46%), Positives = 49/90 (54%), Gaps = 5/90 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G G+PG +G G GPKG G G PGPPG G +G +G G P +QG +G +G Sbjct: 650 GEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG-LPGYPG-RQGPKGSLG 707 Query: 307 PPGAPGRDGSKGER---GAPGPRGSPGPPG 333 PG PG G KG R G GPRG GP G Sbjct: 708 FPGFPGASGEKGARGLSGKSGPRGERGPTG 737 Score = 73.6 bits (179), Expect = 3e-13 Identities = 46/107 (42%), Positives = 47/107 (43%), Gaps = 23/107 (21%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 L GPPG G G PG G GSPG G G G GPRG G GP K GRRG Sbjct: 378 LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPG-----KAGRRGR 432 Query: 305 VGPPGA------------------PGRDGSKGERGAPGPRGSPGPPG 333 G GA PG G KG RG G +G PGPPG Sbjct: 433 AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 479 Score = 72.0 bits (175), Expect = 9e-13 Identities = 45/131 (34%), Positives = 58/131 (44%), Gaps = 27/131 (20%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 LPGP G PG +G G PG G G G PG PG GP+G+ G GP +G +G Sbjct: 1326 LPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGG-----PKGEKGV 1380 Query: 305 VGPPGAPGRDG-----------SKGERGAPGPR-----------GSPGPPGSFDFLLLML 342 GPPG PG G K R G R G+PG PG + + L Sbjct: 1381 QGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSL 1440 Query: 343 ADIRNDITELQ 353 +R +I +++ Sbjct: 1441 DSLREEIEQMR 1451 Score = 70.9 bits (172), Expect = 2e-12 Identities = 41/105 (39%), Positives = 52/105 (49%), Gaps = 1/105 (0%) Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG- 289 K + G + L + G G PG +G G G +G G PG G G GP+G GP G Sbjct: 616 KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 675 Query: 290 PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 P P ++G+ G G PG PGR G KG G PG G+ G G+ Sbjct: 676 PGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGA 720 Score = 65.5 bits (158), Expect = 8e-11 Identities = 40/90 (44%), Positives = 43/90 (47%), Gaps = 15/90 (16%) Query: 249 PGLPGGQGPPGSPGPKGSPGF--PGM--PGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 P GP G G KG P PGM GPPG GP G +GP G QG GP Sbjct: 263 PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGI--------QGNPGP 314 Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 VG PG G G G PG G+PGPPG+ Sbjct: 315 VGDPG---ERGPPGRAGLPGSDGAPGPPGT 341 Score = 56.6 bits (135), Expect = 4e-08 Identities = 45/125 (36%), Positives = 49/125 (39%), Gaps = 40/125 (32%) Query: 247 GPPGLPGGQGPP----------GSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296 GP GL G +G P G PGP+G G G PG G PGP G G GP P + Sbjct: 270 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP-PGRAG 328 Query: 297 IKQGRRGPVGPPGA----PGRDGSKGE------------------------RGAPGPRGS 328 + G G GPPG P R GS G RG PGP G Sbjct: 329 L-PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGY 387 Query: 329 PGPPG 333 G PG Sbjct: 388 TGRPG 392 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 97.1 bits (240), Expect = 3e-20 Identities = 48/88 (54%), Positives = 51/88 (57%), Gaps = 11/88 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG GLPG QGP G PGPKG PG PG G PG PG RG +G QG+ GP Sbjct: 873 PGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVG-----------FQGKTGPP 921 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPG G G+ GE G G RG PGPPG Sbjct: 922 GPPGVVGPQGAAGETGPMGERGHPGPPG 949 Score = 94.0 bits (232), Expect = 2e-19 Identities = 48/92 (52%), Positives = 52/92 (56%), Gaps = 14/92 (15%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 PG PG PG +GP G GPKG+PG FPG PGPPG+ GPRG G +G R Sbjct: 1245 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA-----------KGDR 1293 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G G PG PG G GE G PGP G GP GS Sbjct: 1294 GEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1325 Score = 94.0 bits (232), Expect = 2e-19 Identities = 51/106 (48%), Positives = 55/106 (51%), Gaps = 17/106 (16%) Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMGP 287 TGD N PGP G PG GPPG GP KG G G PG PG PGP G GP Sbjct: 1257 TGDDGPKGN---PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGP 1313 Query: 288 MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G+RGP G PG+ GR G KG +G PG G+PG G Sbjct: 1314 PGP--------LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1351 Score = 93.2 bits (230), Expect = 4e-19 Identities = 47/99 (47%), Positives = 54/99 (54%), Gaps = 11/99 (11%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 G+ T PGPPG+ G QG G GP G G PG PGPPG+ G G+ G Sbjct: 910 GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG-------- 961 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 K+G +G GPPGAPG+DG G RG PG RG PG G Sbjct: 962 ---KEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 997 Score = 90.5 bits (223), Expect = 2e-18 Identities = 56/127 (44%), Positives = 61/127 (48%), Gaps = 28/127 (22%) Query: 235 GDKVLASNTYLPGPPGL---------PGGQGPPGSPGPKGSPGFPGMPGPPGQ------- 278 G K T PGPPGL PG G PG GPKGS GFPG PG G+ Sbjct: 772 GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS 831 Query: 279 --PGPRGSMGPMGP----SPDLSHIKQGRR------GPVGPPGAPGRDGSKGERGAPGPR 326 GPRG GP GP P + K G + GP GPPG G G +G G PGP+ Sbjct: 832 GKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK 891 Query: 327 GSPGPPG 333 G PGPPG Sbjct: 892 GPPGPPG 898 Score = 89.4 bits (220), Expect = 5e-18 Identities = 49/101 (48%), Positives = 55/101 (54%), Gaps = 13/101 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR---GSMGPMGPS-PDLSHIKQGR 301 PGP G PG +G GS GP G PG PG GPPG G + G GP+GP+ D G Sbjct: 1011 PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL 1070 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGS---------PGPPG 333 GP GPPG G DG KGE G PG +G+ PGPPG Sbjct: 1071 PGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1111 Score = 88.6 bits (218), Expect = 9e-18 Identities = 44/87 (50%), Positives = 47/87 (54%), Gaps = 8/87 (9%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GP GLPG GP G GPKG PG PG PG G GP+G G +GP QG GP G Sbjct: 598 GPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGP--------QGEPGPPG 649 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG G G +GA GP G GP G Sbjct: 650 QQGTPGTQGLPGPQGAIGPHGEKGPQG 676 Score = 88.2 bits (217), Expect = 1e-17 Identities = 45/88 (51%), Positives = 53/88 (60%), Gaps = 1/88 (1%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-PDLSHIKQGRRGPV 305 GPPG PG QGPPG+ G KG PG G GP G+ G +G +G GP+ P + G +G V Sbjct: 1030 GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1089 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG G G+KGE G PGP G GP G Sbjct: 1090 GDPGQKGTKGNKGEHGPPGPPGPIGPVG 1117 Score = 86.3 bits (212), Expect = 5e-17 Identities = 42/88 (47%), Positives = 49/88 (55%), Gaps = 1/88 (1%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305 G G G +G PG PG KG GF G+PG PG+ G RG G G P P ++G G + Sbjct: 538 GRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI 597 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G PG G +G G GP G PGPPG Sbjct: 598 GPRGLPGESGPRGLLGPKGPPGIPGPPG 625 Score = 86.3 bits (212), Expect = 5e-17 Identities = 46/96 (47%), Positives = 55/96 (57%), Gaps = 7/96 (7%) Query: 245 LPGPPGL---PGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMG-PSPDLSHI 297 +PGPPG+ G QGP GS GP+G PG PG G PG PGP+G++GP G P Sbjct: 620 IPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 679 Query: 298 KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G GPPG PG++G G +G GP G GP G Sbjct: 680 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLG 715 Score = 85.9 bits (211), Expect = 6e-17 Identities = 44/89 (49%), Positives = 49/89 (55%), Gaps = 2/89 (2%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG PG PG +G G GPKGS G G PGPPGQ G G+ G GP + G +GP Sbjct: 618 PGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG--PHGEKGPQ 675 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G PG PG GS G G PG G PG G+ Sbjct: 676 GKPGLPGMPGSDGPPGHPGKEGPPGTKGN 704 Score = 85.9 bits (211), Expect = 6e-17 Identities = 48/111 (43%), Positives = 56/111 (50%), Gaps = 4/111 (3%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282 P +LG G+K + PG G PG +GP G G KG G PG PGPPG GP Sbjct: 1200 PGGVGNLGP--PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1257 Query: 283 GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP G + G GP G G G+DG+KG+RG G G PG PG Sbjct: 1258 GDDGPKGNPGPVGF--PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPG 1306 Score = 85.5 bits (210), Expect = 8e-17 Identities = 50/110 (45%), Positives = 57/110 (51%), Gaps = 27/110 (24%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---------PGPRGS------------M 285 GPPGLPG +G G+ G KG PG G+ GPPG+ PGP+GS Sbjct: 1393 GPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGAS 1452 Query: 286 GPMGPS--PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP+GP P L G GP G GA G G KGE+G GP G PGPPG Sbjct: 1453 GPIGPGGPPGL----PGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1498 Score = 85.1 bits (209), Expect = 1e-16 Identities = 47/110 (42%), Positives = 53/110 (48%), Gaps = 22/110 (20%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSMGPMGPSPDLSHIKQ 299 PG PG+PG GPPG PG +G PG G GP G PGPRG G G H + Sbjct: 678 PGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGE 737 Query: 300 ----------------GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G RG VG PG+ G DG +G +G GP G PGPPG Sbjct: 738 KGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPG 787 Score = 85.1 bits (209), Expect = 1e-16 Identities = 46/100 (46%), Positives = 50/100 (50%), Gaps = 1/100 (1%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 GDK + G G G GPPG PGP G G PG G G+PG RG G G D Sbjct: 1084 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1143 Query: 295 -SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 + G GP+G G PG G KGE G GP G PGPPG Sbjct: 1144 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPG 1183 Score = 84.7 bits (208), Expect = 1e-16 Identities = 50/131 (38%), Positives = 58/131 (44%), Gaps = 43/131 (32%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG---PRGSMGPMGPSPDLSHI------ 297 GPPG PG G PG PG +G GF G GPPG PG P+G+ G GP + H Sbjct: 892 GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPP 951 Query: 298 ----------KQGRRGPVGPPGAPGRDGSKGERG------------------------AP 323 K+G +G GPPGAPG+DG G RG P Sbjct: 952 GEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 1011 Query: 324 GPRGSPGPPGS 334 GP GSPG G+ Sbjct: 1012 GPAGSPGERGA 1022 Score = 84.3 bits (207), Expect = 2e-16 Identities = 46/103 (44%), Positives = 58/103 (56%), Gaps = 15/103 (14%) Query: 245 LPGPPGLPGGQG------PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PDLSH 296 +PG PG+ G +G PG G +G G G+PGPPG+ G RG G +GP P S Sbjct: 548 MPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESG 607 Query: 297 IKQGRRGPVGPPGAP------GRDGSKGERGAPGPRGSPGPPG 333 +G GP GPPG P G DG +G +G+ GP+G PGPPG Sbjct: 608 -PRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPG 649 Score = 84.0 bits (206), Expect = 2e-16 Identities = 45/100 (45%), Positives = 50/100 (50%), Gaps = 20/100 (20%) Query: 246 PGPPGLPGGQGPP---------GSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296 PGPPG PG GP G PG G PG G GP G PGP GS G G + Sbjct: 969 PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAA----- 1023 Query: 297 IKQGRRGPVGPPGAPGRD---GSKGERGAPGPRGSPGPPG 333 G GP+GPPG PG G+ GE+G PG +G GP G Sbjct: 1024 ---GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTG 1060 Score = 83.6 bits (205), Expect = 3e-16 Identities = 43/87 (49%), Positives = 45/87 (51%), Gaps = 5/87 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GPPG G GPPG G G G PG+ G PG GPRG G G S + G GP G Sbjct: 1198 GPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG-----QPGEPGPPG 1252 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 P G G DG KG G G G PGPPG Sbjct: 1253 PKGPTGDDGPKGNPGPVGFPGDPGPPG 1279 Score = 83.6 bits (205), Expect = 3e-16 Identities = 44/98 (44%), Positives = 51/98 (52%), Gaps = 10/98 (10%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLSHIK----- 298 PG G G GP G PGP G G PG G G+PG G GP GP P L ++ Sbjct: 1347 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA 1406 Query: 299 ---QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G G +G G PG G KG+RG PGP+GSPG G Sbjct: 1407 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKG 1444 Score = 83.2 bits (204), Expect = 4e-16 Identities = 44/92 (47%), Positives = 52/92 (56%), Gaps = 4/92 (4%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPP---GQPGPRGSMGPMG-PSPDLSHIKQGR 301 PGPPG G GP G+ GP+G PG G GPP G+PG GS G G P ++G Sbjct: 1179 PGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGE 1238 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G G PG PG G KG G GP+G+PGP G Sbjct: 1239 KGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG 1270 Score = 82.4 bits (202), Expect = 7e-16 Identities = 44/87 (50%), Positives = 45/87 (51%), Gaps = 11/87 (12%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GPPG G QG PG G KG G G GPPG PGPRG GP G GP G Sbjct: 1150 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGP-----------NGADGPQG 1198 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 PPG G G GE+G PG GSPG G Sbjct: 1199 PPGGVGNLGPPGEKGEPGESGSPGIQG 1225 Score = 81.3 bits (199), Expect = 1e-15 Identities = 44/99 (44%), Positives = 52/99 (52%), Gaps = 10/99 (10%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----PSPDLSHIKQGR 301 PGPPG PG QG PG+ G +G+ G PG PG PG+ GP G G G P +G Sbjct: 945 PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 1004 Query: 302 RGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPGS 334 GP GPPG G G +G G+ GP G GPPG+ Sbjct: 1005 EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGA 1043 Score = 81.3 bits (199), Expect = 1e-15 Identities = 48/118 (40%), Positives = 53/118 (44%), Gaps = 19/118 (16%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----- 289 G K N GPPG PG GP G PG G+ G PG GP G G +G G G Sbjct: 1093 GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP 1152 Query: 290 --------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSP------GPPG 333 P P + G GP+GPPG PG G G GA GP+G P GPPG Sbjct: 1153 GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1210 Score = 80.1 bits (196), Expect = 3e-15 Identities = 46/94 (48%), Positives = 51/94 (54%), Gaps = 13/94 (13%) Query: 247 GPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQ 299 GPPG G +GP GSPG KG+ G PG G PG+ GP G GP G P PD Sbjct: 1312 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPD------ 1365 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G RG G G GR G+ G+ G PGP G PG PG Sbjct: 1366 GLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1399 Score = 79.7 bits (195), Expect = 4e-15 Identities = 45/95 (47%), Positives = 48/95 (50%), Gaps = 8/95 (8%) Query: 246 PGPPGLPGGQG---PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 PG GLPG QG P G GP+G PG PGMPG G PG G GP G + QG Sbjct: 654 PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN-----QGPS 708 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 GP GP G PG G KG G G +G G G F Sbjct: 709 GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 743 Score = 79.3 bits (194), Expect = 6e-15 Identities = 44/101 (43%), Positives = 52/101 (51%), Gaps = 23/101 (22%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP------------PGQPGPRGSMGPMGPSP 292 LPGPPG G +G G GP+G PG GP PG PG RG GP GP Sbjct: 581 LPGPPGEDGERGDDGEIGPRG---LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP-- 635 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G GP G PG PG+ G+ G +G PGP+G+ GP G Sbjct: 636 ------KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHG 670 Score = 76.3 bits (186), Expect = 5e-14 Identities = 46/112 (41%), Positives = 54/112 (48%), Gaps = 20/112 (17%) Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGM------PGPPGQPGPRGSMGP 287 +G+K + GP G G GP G GP+G+ G G GP G PG RG GP Sbjct: 822 SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 881 Query: 288 MGPSPDLSHIKQGRRGPVGPPGAPGRD------GSKGERGAPGPRGSPGPPG 333 GP+ G GP GPPG PG+D G +GE G G G PGPPG Sbjct: 882 QGPN--------GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPG 925 Score = 76.3 bits (186), Expect = 5e-14 Identities = 45/111 (40%), Positives = 50/111 (45%), Gaps = 10/111 (9%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289 + G + A T G G PG GPPG PG G G G PGPPG PG G G G Sbjct: 926 VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRG 985 Query: 290 -------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P +G GP GPPG G G +G G+ GP G PG PG Sbjct: 986 FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 1036 Score = 76.3 bits (186), Expect = 5e-14 Identities = 42/101 (41%), Positives = 49/101 (48%), Gaps = 13/101 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGPSPDLSHI----- 297 PGP GL G GP G G G G G PGPPG GP G+ GP GP + ++ Sbjct: 1152 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGE 1211 Query: 298 -----KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 + G G G PG G G +GE+G G G PGPPG Sbjct: 1212 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG 1252 Score = 75.9 bits (185), Expect = 6e-14 Identities = 46/126 (36%), Positives = 56/126 (44%), Gaps = 39/126 (30%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGS--------------MGPM-- 288 L GPPG+ G GP G PG +G PG G+PG G PGP G+ GP+ Sbjct: 409 LIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVA 468 Query: 289 ------------------GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS-- 328 GP + + GR GP+G PG+PG G G+ G GPRG Sbjct: 469 AQEAQAQAILQQARLALRGPPGPMGY--TGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 526 Query: 329 -PGPPG 333 GPPG Sbjct: 527 LTGPPG 532 Score = 74.7 bits (182), Expect = 1e-13 Identities = 42/93 (45%), Positives = 47/93 (50%), Gaps = 14/93 (15%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGP------PGQPGPRGSMGPMGPSPDLSHIKQG 300 GP G G QGP G PGP G PG G G PGQ G +G+ G GP G Sbjct: 1057 GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP--------PG 1108 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP+GP G PG G+ GE GA GP+G G G Sbjct: 1109 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG 1141 Score = 74.7 bits (182), Expect = 1e-13 Identities = 42/93 (45%), Positives = 49/93 (52%), Gaps = 4/93 (4%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLSHI--KQG 300 LPGP G PG G G G G PG G G G+ GP G GP+GP P + + G Sbjct: 1070 LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPG 1129 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 RGP G GA G +G++G G PGP G G PG Sbjct: 1130 ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPG 1162 Score = 74.3 bits (181), Expect = 2e-13 Identities = 42/90 (46%), Positives = 49/90 (54%), Gaps = 5/90 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G G+PG +G G GPKG G G PGPPG G +G +G G P +QG +G +G Sbjct: 757 GEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG-LPGYPG-RQGPKGSLG 814 Query: 307 PPGAPGRDGSKGER---GAPGPRGSPGPPG 333 PG PG G KG R G GPRG GP G Sbjct: 815 FPGFPGASGEKGARGLSGKSGPRGERGPTG 844 Score = 73.6 bits (179), Expect = 3e-13 Identities = 46/107 (42%), Positives = 47/107 (43%), Gaps = 23/107 (21%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 L GPPG G G PG G GSPG G G G GPRG G GP K GRRG Sbjct: 485 LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPG-----KAGRRGR 539 Query: 305 VGPPGA------------------PGRDGSKGERGAPGPRGSPGPPG 333 G GA PG G KG RG G +G PGPPG Sbjct: 540 AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 586 Score = 72.0 bits (175), Expect = 9e-13 Identities = 45/131 (34%), Positives = 58/131 (44%), Gaps = 27/131 (20%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 LPGP G PG +G G PG G G G PG PG GP+G+ G GP +G +G Sbjct: 1433 LPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGG-----PKGEKGV 1487 Query: 305 VGPPGAPGRDG-----------SKGERGAPGPR-----------GSPGPPGSFDFLLLML 342 GPPG PG G K R G R G+PG PG + + L Sbjct: 1488 QGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSL 1547 Query: 343 ADIRNDITELQ 353 +R +I +++ Sbjct: 1548 DSLREEIEQMR 1558 Score = 70.9 bits (172), Expect = 2e-12 Identities = 41/105 (39%), Positives = 52/105 (49%), Gaps = 1/105 (0%) Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG- 289 K + G + L + G G PG +G G G +G G PG G G GP+G GP G Sbjct: 723 KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 782 Query: 290 PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 P P ++G+ G G PG PGR G KG G PG G+ G G+ Sbjct: 783 PGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGA 827 Score = 64.7 bits (156), Expect = 1e-10 Identities = 39/83 (46%), Positives = 42/83 (50%), Gaps = 15/83 (18%) Query: 256 GPPGSPGPKGSPGF--PGM--PGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAP 311 GP G G KG P PGM GPPG GP G +GP G QG GPVG PG Sbjct: 377 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGI--------QGNPGPVGDPG-- 426 Query: 312 GRDGSKGERGAPGPRGSPGPPGS 334 G G G PG G+PGPPG+ Sbjct: 427 -ERGPPGRAGLPGSDGAPGPPGT 448 Score = 56.6 bits (135), Expect = 4e-08 Identities = 45/125 (36%), Positives = 49/125 (39%), Gaps = 40/125 (32%) Query: 247 GPPGLPGGQGPP----------GSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296 GP GL G +G P G PGP+G G G PG G PGP G G GP P + Sbjct: 377 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP-PGRAG 435 Query: 297 IKQGRRGPVGPPGA----PGRDGSKGE------------------------RGAPGPRGS 328 + G G GPPG P R GS G RG PGP G Sbjct: 436 L-PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGY 494 Query: 329 PGPPG 333 G PG Sbjct: 495 TGRPG 499 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 97.1 bits (240), Expect = 3e-20 Identities = 48/93 (51%), Positives = 55/93 (59%), Gaps = 11/93 (11%) Query: 247 GPPGLPGGQGP------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300 GPPG+ G G PGSPGP G+PG PGM G PG PGP G++GP GP K G Sbjct: 1340 GPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRG-----KPG 1394 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 + G G PG G G+KG +G PGP GS G PG Sbjct: 1395 KDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPG 1427 Score = 90.9 bits (224), Expect = 2e-18 Identities = 54/124 (43%), Positives = 60/124 (48%), Gaps = 11/124 (8%) Query: 246 PGPPGLPGGQGP------PGSPGPKGSPGFPGMPGP---PGQPGPRGSMGPMGPSPDLSH 296 PG PG PG GP PG G KG GFPG+PG PG PG G G G Sbjct: 105 PGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164 Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQEKV 356 I+ +G G PGAPG G G G PGP G PGPPG F F M R + E+V Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM--GPRGPKGHMGERV 222 Query: 357 FGHR 360 GH+ Sbjct: 223 IGHK 226 Score = 89.4 bits (220), Expect = 5e-18 Identities = 52/111 (46%), Positives = 57/111 (51%), Gaps = 4/111 (3%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282 P A D+G G LPGP G PG QG PG G KG+PGF G GPPG GP+ Sbjct: 1282 PGTAGDMGP--PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339 Query: 283 GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G G L I G GPPG PG G +GE G PGP G+ GP G Sbjct: 1340 GPPGVRGDPGTLKII--SLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCG 1388 Score = 88.2 bits (217), Expect = 1e-17 Identities = 48/104 (46%), Positives = 54/104 (51%), Gaps = 17/104 (16%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI------KQG 300 G PGLPG GP G PGP G PG G PGPPG G G+MGP GP + ++G Sbjct: 171 GDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERG 230 Query: 301 RRGPVGPPGAPG-----------RDGSKGERGAPGPRGSPGPPG 333 +G GPPG PG R KGE+G G G PGPPG Sbjct: 231 VKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274 Score = 86.7 bits (213), Expect = 4e-17 Identities = 45/92 (48%), Positives = 48/92 (52%), Gaps = 4/92 (4%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG GLPG +G G KG G PG PG PG PGP G GP G P QG +G Sbjct: 574 PGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVP 633 Query: 306 GPPGAPGRDGSKGERG----APGPRGSPGPPG 333 G PG PG G +GE PGP G PGPPG Sbjct: 634 GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665 Score = 86.3 bits (212), Expect = 5e-17 Identities = 50/111 (45%), Positives = 54/111 (48%), Gaps = 10/111 (9%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282 P D G + GD PGPPG G GP G+PG GSPG PG PGP G G + Sbjct: 1067 PGPTGDPG--LPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFK 1124 Query: 283 GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G +GP G RGP G PG PG G G RG G G PGP G Sbjct: 1125 GIKGLLGP--------PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAG 1167 Score = 85.9 bits (211), Expect = 6e-17 Identities = 45/97 (46%), Positives = 52/97 (53%), Gaps = 5/97 (5%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG PG QGPPG PG G G PG+PGP G+PG G P P P G +G + Sbjct: 661 PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSL 720 Query: 306 GPPGAPGRDGSKGERGAPGPRGS-----PGPPGSFDF 337 G PG G G G+ G PG +G PG PG+ F Sbjct: 721 GCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGF 757 Score = 85.1 bits (209), Expect = 1e-16 Identities = 51/124 (41%), Positives = 63/124 (50%), Gaps = 15/124 (12%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282 P N LG G+ + PG G PG G PG+PG +GSPG PG+ G G PG + Sbjct: 876 PGNPGILGP--PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAK 933 Query: 283 GSMGPMG-PSP-DLSHI-----KQGRRGPVGPP------GAPGRDGSKGERGAPGPRGSP 329 G G G P P ++SH+ + G +G G P G PG G KG +G PGP G P Sbjct: 934 GEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPP 993 Query: 330 GPPG 333 GP G Sbjct: 994 GPRG 997 Score = 85.1 bits (209), Expect = 1e-16 Identities = 50/115 (43%), Positives = 53/115 (46%), Gaps = 23/115 (20%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG-----------PRGSMGPMG----P 290 PG PGLPG +G G GP+G G G PGPPG PG P GS G G P Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256 Query: 291 SPDLSHI--------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 P SH+ G GP GPPG G G G GAPG G PGP G F Sbjct: 1257 GPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGF 1311 Score = 84.0 bits (206), Expect = 2e-16 Identities = 43/89 (48%), Positives = 46/89 (51%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 L G PG G G PGS G +G+ GFPG G PG PG G G G + G GP Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP 1069 Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG PG G KGE G PGP G GP G Sbjct: 1070 TGDPGLPGDMGKKGEMGQPGPPGHLGPAG 1098 Score = 83.6 bits (205), Expect = 3e-16 Identities = 48/93 (51%), Positives = 53/93 (56%), Gaps = 6/93 (6%) Query: 246 PGPPGLPGGQG---PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--PSPDLSHIKQG 300 PGPPG PG +G P G PGP+G GFPG+PG G G RG G G SP L G Sbjct: 54 PGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPG-TPG 112 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G G PG GSKGE+G PG G+ G PG Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145 Score = 83.2 bits (204), Expect = 4e-16 Identities = 48/112 (42%), Positives = 52/112 (46%), Gaps = 23/112 (20%) Query: 245 LPGPPGLPG--GQGPPGSPGPKGSPGFPG---------------MPGPPGQPGPRGSM-- 285 LPGP G PG G G PG PGPKG GFPG +PG PG PG +G Sbjct: 687 LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAV 746 Query: 286 ----GPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP P G G +G PG PG G+ G G GPRG PG PG Sbjct: 747 AMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG 798 Score = 83.2 bits (204), Expect = 4e-16 Identities = 46/111 (41%), Positives = 57/111 (51%), Gaps = 7/111 (6%) Query: 230 GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289 G ++ G K + PGP G PG G G PG G+PG PG+PGP G PG +G G G Sbjct: 1260 GSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKG 1319 Query: 290 PSPDLSHIKQ-GRRGPVGPPGAPGRDGSKGE------RGAPGPRGSPGPPG 333 + + G GP+GP G PG G G G+PGP G+PG PG Sbjct: 1320 EKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPG 1370 Score = 82.8 bits (203), Expect = 5e-16 Identities = 52/124 (41%), Positives = 60/124 (48%), Gaps = 23/124 (18%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---- 278 P DLG G K L + GPPGLPG G PG G +G G G+PGP G+ Sbjct: 1115 PGPHGDLG--FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGET 1172 Query: 279 ------PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGP---RGSP 329 PGPRG+ G G +G RG G PG PGR G+ G+ G GP G P Sbjct: 1173 GLLRAPPGPRGNPGAQG--------AKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFP 1224 Query: 330 GPPG 333 GPPG Sbjct: 1225 GPPG 1228 Score = 82.8 bits (203), Expect = 5e-16 Identities = 53/111 (47%), Positives = 58/111 (52%), Gaps = 23/111 (20%) Query: 246 PGPPGLPG----GQ-GPPGSPGPKGSPGFPGMPGPPGQ-----PGPRGSMGPMGPS-PDL 294 PGPPGLPG GQ G G PG +GSPG PG PGPPG G +GSMG GP P Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPG 1283 Query: 295 SHIKQGRRGPVGPPGAPGRDGS------------KGERGAPGPRGSPGPPG 333 + G G +G PG PG G KGE+G PG GS GPPG Sbjct: 1284 TAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334 Score = 82.4 bits (202), Expect = 7e-16 Identities = 44/97 (45%), Positives = 49/97 (50%), Gaps = 27/97 (27%) Query: 246 PGPPGLPG--------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI 297 PG PG PG G GP G PG +G+ G PG PGPPG+ GPRG + P P Sbjct: 601 PGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVP----- 655 Query: 298 KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 GP GPPG PG PGP+G PG PGS Sbjct: 656 -----GPPGPPGPPGH---------PGPQGPPGIPGS 678 Score = 82.4 bits (202), Expect = 7e-16 Identities = 47/98 (47%), Positives = 52/98 (53%), Gaps = 15/98 (15%) Query: 239 LASNTYLPGPPGLPGGQGPPGSPGPKGSPGFP---GMPGPPGQPGPRGSMGPMGPSPDLS 295 L+ +T +PGPPG P GPPG PGP+G PG P G G PG PGP G G G Sbjct: 648 LSVSTPVPGPPGPP---GPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG------ 698 Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP GP G G G+KG G PG G PG PG Sbjct: 699 ---IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPG 733 Score = 81.3 bits (199), Expect = 1e-15 Identities = 52/113 (46%), Positives = 57/113 (50%), Gaps = 28/113 (24%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG-----PRGSMGPMGPSPDLSHIK- 298 LPG PGLPG G G GP+G PG PG PG G PG PRG+ G P L+ +K Sbjct: 772 LPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQG----LPGLNGLKG 827 Query: 299 -QGRRGPVGPPGAPG-----RDGSKGERGAPG------------PRGSPGPPG 333 QGRRG GP G PG R G GE G+PG RG PG PG Sbjct: 828 QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPG 880 Score = 80.9 bits (198), Expect = 2e-15 Identities = 51/128 (39%), Positives = 58/128 (45%), Gaps = 38/128 (29%) Query: 244 YLPGPPGLPGG------------------QGPPGSPGPKGSPGFPGMPGPPGQPGPRGSM 285 Y+PGPPGLPG +G PGSPG G PGFPG PG G PG +G Sbjct: 481 YIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEK 540 Query: 286 G----PMG----PSPDLSHIKQGRRGPVGPPGAPG------------RDGSKGERGAPGP 325 G P G P + GR+G G PG PG G KG++G PG Sbjct: 541 GETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGD 600 Query: 326 RGSPGPPG 333 GSPG PG Sbjct: 601 PGSPGSPG 608 Score = 80.1 bits (196), Expect = 3e-15 Identities = 44/95 (46%), Positives = 53/95 (55%), Gaps = 13/95 (13%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 L PPG G G G+ G +G+PGFPG+PG G G G GP G +G GP Sbjct: 1175 LRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTG--------IEGFPGP 1226 Query: 305 VGPPGA--PGRDGSK---GERGAPGPRGSPGPPGS 334 G PGA PG+ G++ G RG+PG G PGPPGS Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261 Score = 79.3 bits (194), Expect = 6e-15 Identities = 47/115 (40%), Positives = 53/115 (46%), Gaps = 26/115 (22%) Query: 245 LPGPPGLPG-----------GQGPPGSPGPKGS------------PGFPGMPGPPGQPGP 281 LPG PGLPG G G PG PG +G+ PG PG PG G GP Sbjct: 731 LPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP 790 Query: 282 RGSMGPMGPSPDL---SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 RG G GP + +G RG G PG G G +G RG GP+G PG PG Sbjct: 791 RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPG 845 Score = 78.6 bits (192), Expect = 1e-14 Identities = 40/88 (45%), Positives = 47/88 (53%), Gaps = 11/88 (12%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G PG+PG QG G G +G PG PG+ GPPG+ G G MG G GP G Sbjct: 856 GSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMG-----------FPGAIGPPG 904 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGS 334 PPG PG G +G G PG +G G PG+ Sbjct: 905 PPGNPGTPGQRGSPGIPGVKGQRGTPGA 932 Score = 78.2 bits (191), Expect = 1e-14 Identities = 43/106 (40%), Positives = 55/106 (51%), Gaps = 1/106 (0%) Query: 230 GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289 G+ +K + L G PG G G PGS G KG+ GFPG+ G G G +G +GP G Sbjct: 280 GESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPG 339 Query: 290 -PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 P + +G G PG PG G++G +G GP G PG PGS Sbjct: 340 FRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385 Score = 77.8 bits (190), Expect = 2e-14 Identities = 46/95 (48%), Positives = 51/95 (53%), Gaps = 16/95 (16%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGF--PGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRR 302 PGP G G QGP G PG GSPG PG+ G PG PG +GS G G P D Sbjct: 362 PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDA-------- 413 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 +G PG+PG GS G G+PGP PGPPG F Sbjct: 414 --MGTPGSPGCAGSPGLPGSPGP---PGPPGDIVF 443 Score = 77.4 bits (189), Expect = 2e-14 Identities = 49/107 (45%), Positives = 52/107 (48%), Gaps = 26/107 (24%) Query: 246 PGPPGLPGGQGP-----------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 PG PGL G +G PGSPG GSPG PG PGPPG PG + GP D Sbjct: 394 PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPG--DIVFRKGPPGD- 450 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERG--------APGPRGSPGPPG 333 G G +G PG PG DG KGE G PGP G PG PG Sbjct: 451 ----HGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493 Score = 77.0 bits (188), Expect = 3e-14 Identities = 48/123 (39%), Positives = 55/123 (44%), Gaps = 33/123 (26%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPG--------FPGMPGPPGQPGPRGSMGPMG------- 289 LPG GL G QG G GPKG PG FPG G PG PG +G MGP+G Sbjct: 819 LPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGN 878 Query: 290 ------PSPDLSHIKQGRRGPVGPPGAPGRDGS------------KGERGAPGPRGSPGP 331 P D G G +GPPG PG G+ KG+RG PG +G G Sbjct: 879 PGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGD 938 Query: 332 PGS 334 G+ Sbjct: 939 KGN 941 Score = 76.6 bits (187), Expect = 4e-14 Identities = 39/84 (46%), Positives = 45/84 (53%), Gaps = 5/84 (5%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG PG G G PGP G PG G GP G+PG G G GP+ + +G +G Sbjct: 1360 PGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGE-----KGNKGSK 1414 Query: 306 GPPGAPGRDGSKGERGAPGPRGSP 329 G PG G DG G +G G GSP Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSGSP 1438 Score = 75.5 bits (184), Expect = 8e-14 Identities = 52/124 (41%), Positives = 57/124 (45%), Gaps = 38/124 (30%) Query: 247 GPPGLPGGQGP---PGSPGPKGS---------PGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 GP GLPG QGP PG PG GS PGF G PG PG PG G G +G P Sbjct: 67 GPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVG-VPGC 125 Query: 295 SHIK-----QGRRGPVGPPGAPGRDGSKGER--------------------GAPGPRGSP 329 S K G G +G PG PG G KG++ GAPGP+G P Sbjct: 126 SGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLP 185 Query: 330 GPPG 333 GPPG Sbjct: 186 GPPG 189 Score = 75.5 bits (184), Expect = 8e-14 Identities = 44/103 (42%), Positives = 49/103 (47%), Gaps = 11/103 (10%) Query: 242 NTYLPGPPGLPGGQGPPGS--------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPD 293 N L GP G PG GPPG GP+G+ G PG+ G GQ G RG GP G Sbjct: 784 NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGI 843 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSK---GERGAPGPRGSPGPPG 333 + G G G PG PG G G+RG PG G GPPG Sbjct: 844 PGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPG 886 Score = 74.7 bits (182), Expect = 1e-13 Identities = 44/92 (47%), Positives = 50/92 (54%), Gaps = 3/92 (3%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRG 303 +PG GL G GP G PGP+G G G PG PG G GSMG MG P G G Sbjct: 977 MPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036 Query: 304 PVGPPGAPGRDGSKGERGAPG-PRGS-PGPPG 333 G PG PG G +G++G PG G+ PGPPG Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG 1068 Score = 74.3 bits (181), Expect = 2e-13 Identities = 44/102 (43%), Positives = 50/102 (49%), Gaps = 5/102 (4%) Query: 232 YITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS 291 ++ GDK G PG G +G PG PG KG G PG GPPG G GS G G Sbjct: 949 HVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPG-E 1007 Query: 292 PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P L +G G +G G PG G +G G PG G PG PG Sbjct: 1008 PGL----RGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045 Score = 73.9 bits (180), Expect = 2e-13 Identities = 46/109 (42%), Positives = 52/109 (47%), Gaps = 10/109 (9%) Query: 235 GDKVLASNTYLPGPPGLPG-------GQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGS 284 G A + LPG PG PG +GPPG PG GSPG PG+ GP G+PG + Sbjct: 418 GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCT 477 Query: 285 MGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P P P G G G PG G G KG G+PG G PG PG Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPG 526 Score = 73.6 bits (179), Expect = 3e-13 Identities = 52/143 (36%), Positives = 58/143 (40%), Gaps = 38/143 (26%) Query: 222 LPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF-----PGMPGPP 276 +P + ++G + G K PG G PG G G G KG PG+ PG PGP Sbjct: 1013 IPGSMGNMG--MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPT 1070 Query: 277 GQPGPRGSMGPMG----PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS---- 328 G PG G MG G P P G GP GP GAPG GS G G PGP G Sbjct: 1071 GDPGLPGDMGKKGEMGQPGPP------GHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFK 1124 Query: 329 -----------------PGPPGS 334 PG PGS Sbjct: 1125 GIKGLLGPPGIRGPPGLPGFPGS 1147 Score = 70.9 bits (172), Expect = 2e-12 Identities = 44/108 (40%), Positives = 48/108 (44%), Gaps = 20/108 (18%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPD--LSHIKQGRR 302 PGP G PG QG G G G PG PG G G GPRG G G P P I G+ Sbjct: 1179 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1238 Query: 303 GPVGPPGAPGRDGS-----------------KGERGAPGPRGSPGPPG 333 G GPPG+ G G+ KG G PGP+G PG G Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286 Score = 68.6 bits (166), Expect = 1e-11 Identities = 45/119 (37%), Positives = 54/119 (45%), Gaps = 26/119 (21%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGG-----QGPPGSPGPKGSPGFPGMPGPPG 277 P+N DL K GDK PGP GLPG +G PG PG +G PG G+PG PG Sbjct: 251 PDNRTDL-KGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPG 309 Query: 278 QPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFD 336 G +G+ G PG G DG KG++G GP G GP +D Sbjct: 310 SEGVKGNRGF--------------------PGLMGEDGIKGQKGDIGPPGFRGPTEYYD 348 Score = 68.2 bits (165), Expect = 1e-11 Identities = 38/76 (50%), Positives = 41/76 (53%), Gaps = 11/76 (14%) Query: 262 GPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERG 321 G KG G G PGPPG PG +G GP G G +GP G PG PG GSKG RG Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEG--------LPGPQGPKGFPGLPGLTGSKGVRG 94 Query: 322 A---PGPRGSPGPPGS 334 PG GSPG PG+ Sbjct: 95 ISGLPGFSGSPGLPGT 110 Score = 67.8 bits (164), Expect = 2e-11 Identities = 48/126 (38%), Positives = 52/126 (41%), Gaps = 29/126 (23%) Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF----------------PGMPG 274 K I G + A PG PG G G PG PG +G PG PG PG Sbjct: 498 KGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPG 557 Query: 275 PPGQPGPRGSMGPMG-------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRG 327 GQPG +G G G P P G +G GPPG PG GS PGP G Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS------PGPAG 611 Query: 328 SPGPPG 333 GPPG Sbjct: 612 PAGPPG 617 Score = 65.1 bits (157), Expect = 1e-10 Identities = 47/111 (42%), Positives = 53/111 (47%), Gaps = 14/111 (12%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGS--------PGPKGSPGFPGMPGPPGQPGPRGSMG 286 GD L PG PG+ G +G PG PGP G PG PG+ G G PG +G+ G Sbjct: 449 GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508 Query: 287 PMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERG----APGPRGSPGPPG 333 G SP S G G G PGA G G KGE+G G G PG PG Sbjct: 509 LKG-SPG-SPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPG 557 Score = 60.5 bits (145), Expect = 3e-09 Identities = 51/163 (31%), Positives = 57/163 (34%), Gaps = 70/163 (42%) Query: 245 LPGPPGLPGGQGPPGSPG-----------------------PKGSPGFPGMPGPPGQPGP 281 LPGPPG PG GPPG PG KG G G+ GPPG PG Sbjct: 184 LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243 Query: 282 -----------------------RGSMGPMGPS--PDLSHIK----------QGRRGPVG 306 G GP GPS P S+ QG+ G G Sbjct: 244 VIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDG 303 Query: 307 PPGAPGRDGSKGERGAPG------------PRGSPGPPGSFDF 337 PG PG +G KG RG PG G PG G ++ Sbjct: 304 VPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346 Score = 40.4 bits (93), Expect = 0.003 Identities = 18/38 (47%), Positives = 21/38 (55%) Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 G +G G G PG GS G++G GP G PGP G F Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGF 80 Score = 30.4 bits (67), Expect = 3.0 Identities = 14/23 (60%), Positives = 16/23 (69%), Gaps = 3/23 (13%) Query: 314 DGSKGERGA---PGPRGSPGPPG 333 DG+KGE+G PGP GSPG G Sbjct: 42 DGAKGEKGEKGFPGPPGSPGQKG 64 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 97.1 bits (240), Expect = 3e-20 Identities = 48/93 (51%), Positives = 55/93 (59%), Gaps = 11/93 (11%) Query: 247 GPPGLPGGQGP------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300 GPPG+ G G PGSPGP G+PG PGM G PG PGP G++GP GP K G Sbjct: 1340 GPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRG-----KPG 1394 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 + G G PG G G+KG +G PGP GS G PG Sbjct: 1395 KDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPG 1427 Score = 90.9 bits (224), Expect = 2e-18 Identities = 54/124 (43%), Positives = 60/124 (48%), Gaps = 11/124 (8%) Query: 246 PGPPGLPGGQGP------PGSPGPKGSPGFPGMPGP---PGQPGPRGSMGPMGPSPDLSH 296 PG PG PG GP PG G KG GFPG+PG PG PG G G G Sbjct: 105 PGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164 Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQEKV 356 I+ +G G PGAPG G G G PGP G PGPPG F F M R + E+V Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM--GPRGPKGHMGERV 222 Query: 357 FGHR 360 GH+ Sbjct: 223 IGHK 226 Score = 89.4 bits (220), Expect = 5e-18 Identities = 52/111 (46%), Positives = 57/111 (51%), Gaps = 4/111 (3%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282 P A D+G G LPGP G PG QG PG G KG+PGF G GPPG GP+ Sbjct: 1282 PGTAGDMGP--PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339 Query: 283 GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G G L I G GPPG PG G +GE G PGP G+ GP G Sbjct: 1340 GPPGVRGDPGTLKII--SLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCG 1388 Score = 88.2 bits (217), Expect = 1e-17 Identities = 48/104 (46%), Positives = 54/104 (51%), Gaps = 17/104 (16%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI------KQG 300 G PGLPG GP G PGP G PG G PGPPG G G+MGP GP + ++G Sbjct: 171 GDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERG 230 Query: 301 RRGPVGPPGAPG-----------RDGSKGERGAPGPRGSPGPPG 333 +G GPPG PG R KGE+G G G PGPPG Sbjct: 231 VKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274 Score = 86.7 bits (213), Expect = 4e-17 Identities = 45/92 (48%), Positives = 48/92 (52%), Gaps = 4/92 (4%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG GLPG +G G KG G PG PG PG PGP G GP G P QG +G Sbjct: 574 PGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVP 633 Query: 306 GPPGAPGRDGSKGERG----APGPRGSPGPPG 333 G PG PG G +GE PGP G PGPPG Sbjct: 634 GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665 Score = 86.3 bits (212), Expect = 5e-17 Identities = 50/111 (45%), Positives = 54/111 (48%), Gaps = 10/111 (9%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282 P D G + GD PGPPG G GP G+PG GSPG PG PGP G G + Sbjct: 1067 PGPTGDPG--LPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFK 1124 Query: 283 GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G +GP G RGP G PG PG G G RG G G PGP G Sbjct: 1125 GIKGLLGP--------PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAG 1167 Score = 85.9 bits (211), Expect = 6e-17 Identities = 45/97 (46%), Positives = 52/97 (53%), Gaps = 5/97 (5%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG PG QGPPG PG G G PG+PGP G+PG G P P P G +G + Sbjct: 661 PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSL 720 Query: 306 GPPGAPGRDGSKGERGAPGPRGS-----PGPPGSFDF 337 G PG G G G+ G PG +G PG PG+ F Sbjct: 721 GCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGF 757 Score = 85.1 bits (209), Expect = 1e-16 Identities = 51/124 (41%), Positives = 63/124 (50%), Gaps = 15/124 (12%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282 P N LG G+ + PG G PG G PG+PG +GSPG PG+ G G PG + Sbjct: 876 PGNPGILGP--PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAK 933 Query: 283 GSMGPMG-PSP-DLSHI-----KQGRRGPVGPP------GAPGRDGSKGERGAPGPRGSP 329 G G G P P ++SH+ + G +G G P G PG G KG +G PGP G P Sbjct: 934 GEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPP 993 Query: 330 GPPG 333 GP G Sbjct: 994 GPRG 997 Score = 85.1 bits (209), Expect = 1e-16 Identities = 50/115 (43%), Positives = 53/115 (46%), Gaps = 23/115 (20%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG-----------PRGSMGPMG----P 290 PG PGLPG +G G GP+G G G PGPPG PG P GS G G P Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256 Query: 291 SPDLSHI--------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 P SH+ G GP GPPG G G G GAPG G PGP G F Sbjct: 1257 GPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGF 1311 Score = 84.0 bits (206), Expect = 2e-16 Identities = 43/89 (48%), Positives = 46/89 (51%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 L G PG G G PGS G +G+ GFPG G PG PG G G G + G GP Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP 1069 Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG PG G KGE G PGP G GP G Sbjct: 1070 TGDPGLPGDMGKKGEMGQPGPPGHLGPAG 1098 Score = 83.6 bits (205), Expect = 3e-16 Identities = 48/93 (51%), Positives = 53/93 (56%), Gaps = 6/93 (6%) Query: 246 PGPPGLPGGQG---PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--PSPDLSHIKQG 300 PGPPG PG +G P G PGP+G GFPG+PG G G RG G G SP L G Sbjct: 54 PGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPG-TPG 112 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G G PG GSKGE+G PG G+ G PG Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145 Score = 83.2 bits (204), Expect = 4e-16 Identities = 48/112 (42%), Positives = 52/112 (46%), Gaps = 23/112 (20%) Query: 245 LPGPPGLPG--GQGPPGSPGPKGSPGFPG---------------MPGPPGQPGPRGSM-- 285 LPGP G PG G G PG PGPKG GFPG +PG PG PG +G Sbjct: 687 LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAV 746 Query: 286 ----GPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP P G G +G PG PG G+ G G GPRG PG PG Sbjct: 747 AMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG 798 Score = 83.2 bits (204), Expect = 4e-16 Identities = 46/111 (41%), Positives = 57/111 (51%), Gaps = 7/111 (6%) Query: 230 GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289 G ++ G K + PGP G PG G G PG G+PG PG+PGP G PG +G G G Sbjct: 1260 GSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKG 1319 Query: 290 PSPDLSHIKQ-GRRGPVGPPGAPGRDGSKGE------RGAPGPRGSPGPPG 333 + + G GP+GP G PG G G G+PGP G+PG PG Sbjct: 1320 EKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPG 1370 Score = 82.8 bits (203), Expect = 5e-16 Identities = 52/124 (41%), Positives = 60/124 (48%), Gaps = 23/124 (18%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---- 278 P DLG G K L + GPPGLPG G PG G +G G G+PGP G+ Sbjct: 1115 PGPHGDLG--FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGET 1172 Query: 279 ------PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGP---RGSP 329 PGPRG+ G G +G RG G PG PGR G+ G+ G GP G P Sbjct: 1173 GLLRAPPGPRGNPGAQG--------AKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFP 1224 Query: 330 GPPG 333 GPPG Sbjct: 1225 GPPG 1228 Score = 82.8 bits (203), Expect = 5e-16 Identities = 53/111 (47%), Positives = 58/111 (52%), Gaps = 23/111 (20%) Query: 246 PGPPGLPG----GQ-GPPGSPGPKGSPGFPGMPGPPGQ-----PGPRGSMGPMGPS-PDL 294 PGPPGLPG GQ G G PG +GSPG PG PGPPG G +GSMG GP P Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPG 1283 Query: 295 SHIKQGRRGPVGPPGAPGRDGS------------KGERGAPGPRGSPGPPG 333 + G G +G PG PG G KGE+G PG GS GPPG Sbjct: 1284 TAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334 Score = 82.4 bits (202), Expect = 7e-16 Identities = 44/97 (45%), Positives = 49/97 (50%), Gaps = 27/97 (27%) Query: 246 PGPPGLPG--------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI 297 PG PG PG G GP G PG +G+ G PG PGPPG+ GPRG + P P Sbjct: 601 PGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVP----- 655 Query: 298 KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 GP GPPG PG PGP+G PG PGS Sbjct: 656 -----GPPGPPGPPGH---------PGPQGPPGIPGS 678 Score = 82.4 bits (202), Expect = 7e-16 Identities = 47/98 (47%), Positives = 52/98 (53%), Gaps = 15/98 (15%) Query: 239 LASNTYLPGPPGLPGGQGPPGSPGPKGSPGFP---GMPGPPGQPGPRGSMGPMGPSPDLS 295 L+ +T +PGPPG P GPPG PGP+G PG P G G PG PGP G G G Sbjct: 648 LSVSTPVPGPPGPP---GPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG------ 698 Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP GP G G G+KG G PG G PG PG Sbjct: 699 ---IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPG 733 Score = 81.3 bits (199), Expect = 1e-15 Identities = 52/113 (46%), Positives = 57/113 (50%), Gaps = 28/113 (24%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG-----PRGSMGPMGPSPDLSHIK- 298 LPG PGLPG G G GP+G PG PG PG G PG PRG+ G P L+ +K Sbjct: 772 LPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQG----LPGLNGLKG 827 Query: 299 -QGRRGPVGPPGAPG-----RDGSKGERGAPG------------PRGSPGPPG 333 QGRRG GP G PG R G GE G+PG RG PG PG Sbjct: 828 QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPG 880 Score = 80.9 bits (198), Expect = 2e-15 Identities = 51/128 (39%), Positives = 58/128 (45%), Gaps = 38/128 (29%) Query: 244 YLPGPPGLPGG------------------QGPPGSPGPKGSPGFPGMPGPPGQPGPRGSM 285 Y+PGPPGLPG +G PGSPG G PGFPG PG G PG +G Sbjct: 481 YIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEK 540 Query: 286 G----PMG----PSPDLSHIKQGRRGPVGPPGAPG------------RDGSKGERGAPGP 325 G P G P + GR+G G PG PG G KG++G PG Sbjct: 541 GETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGD 600 Query: 326 RGSPGPPG 333 GSPG PG Sbjct: 601 PGSPGSPG 608 Score = 80.1 bits (196), Expect = 3e-15 Identities = 44/95 (46%), Positives = 53/95 (55%), Gaps = 13/95 (13%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 L PPG G G G+ G +G+PGFPG+PG G G G GP G +G GP Sbjct: 1175 LRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTG--------IEGFPGP 1226 Query: 305 VGPPGA--PGRDGSK---GERGAPGPRGSPGPPGS 334 G PGA PG+ G++ G RG+PG G PGPPGS Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261 Score = 79.3 bits (194), Expect = 6e-15 Identities = 47/115 (40%), Positives = 53/115 (46%), Gaps = 26/115 (22%) Query: 245 LPGPPGLPG-----------GQGPPGSPGPKGS------------PGFPGMPGPPGQPGP 281 LPG PGLPG G G PG PG +G+ PG PG PG G GP Sbjct: 731 LPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP 790 Query: 282 RGSMGPMGPSPDL---SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 RG G GP + +G RG G PG G G +G RG GP+G PG PG Sbjct: 791 RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPG 845 Score = 78.6 bits (192), Expect = 1e-14 Identities = 40/88 (45%), Positives = 47/88 (53%), Gaps = 11/88 (12%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G PG+PG QG G G +G PG PG+ GPPG+ G G MG G GP G Sbjct: 856 GSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMG-----------FPGAIGPPG 904 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGS 334 PPG PG G +G G PG +G G PG+ Sbjct: 905 PPGNPGTPGQRGSPGIPGVKGQRGTPGA 932 Score = 78.2 bits (191), Expect = 1e-14 Identities = 43/106 (40%), Positives = 55/106 (51%), Gaps = 1/106 (0%) Query: 230 GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289 G+ +K + L G PG G G PGS G KG+ GFPG+ G G G +G +GP G Sbjct: 280 GESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPG 339 Query: 290 -PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 P + +G G PG PG G++G +G GP G PG PGS Sbjct: 340 FRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385 Score = 77.8 bits (190), Expect = 2e-14 Identities = 46/95 (48%), Positives = 51/95 (53%), Gaps = 16/95 (16%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGF--PGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRR 302 PGP G G QGP G PG GSPG PG+ G PG PG +GS G G P D Sbjct: 362 PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDA-------- 413 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 +G PG+PG GS G G+PGP PGPPG F Sbjct: 414 --MGTPGSPGCAGSPGLPGSPGP---PGPPGDIVF 443 Score = 77.4 bits (189), Expect = 2e-14 Identities = 49/107 (45%), Positives = 52/107 (48%), Gaps = 26/107 (24%) Query: 246 PGPPGLPGGQGP-----------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 PG PGL G +G PGSPG GSPG PG PGPPG PG + GP D Sbjct: 394 PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPG--DIVFRKGPPGD- 450 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERG--------APGPRGSPGPPG 333 G G +G PG PG DG KGE G PGP G PG PG Sbjct: 451 ----HGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493 Score = 77.0 bits (188), Expect = 3e-14 Identities = 48/123 (39%), Positives = 55/123 (44%), Gaps = 33/123 (26%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPG--------FPGMPGPPGQPGPRGSMGPMG------- 289 LPG GL G QG G GPKG PG FPG G PG PG +G MGP+G Sbjct: 819 LPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGN 878 Query: 290 ------PSPDLSHIKQGRRGPVGPPGAPGRDGS------------KGERGAPGPRGSPGP 331 P D G G +GPPG PG G+ KG+RG PG +G G Sbjct: 879 PGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGD 938 Query: 332 PGS 334 G+ Sbjct: 939 KGN 941 Score = 76.6 bits (187), Expect = 4e-14 Identities = 39/84 (46%), Positives = 45/84 (53%), Gaps = 5/84 (5%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG PG G G PGP G PG G GP G+PG G G GP+ + +G +G Sbjct: 1360 PGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGE-----KGNKGSK 1414 Query: 306 GPPGAPGRDGSKGERGAPGPRGSP 329 G PG G DG G +G G GSP Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSGSP 1438 Score = 75.5 bits (184), Expect = 8e-14 Identities = 52/124 (41%), Positives = 57/124 (45%), Gaps = 38/124 (30%) Query: 247 GPPGLPGGQGP---PGSPGPKGS---------PGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 GP GLPG QGP PG PG GS PGF G PG PG PG G G +G P Sbjct: 67 GPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVG-VPGC 125 Query: 295 SHIK-----QGRRGPVGPPGAPGRDGSKGER--------------------GAPGPRGSP 329 S K G G +G PG PG G KG++ GAPGP+G P Sbjct: 126 SGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLP 185 Query: 330 GPPG 333 GPPG Sbjct: 186 GPPG 189 Score = 75.5 bits (184), Expect = 8e-14 Identities = 44/103 (42%), Positives = 49/103 (47%), Gaps = 11/103 (10%) Query: 242 NTYLPGPPGLPGGQGPPGS--------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPD 293 N L GP G PG GPPG GP+G+ G PG+ G GQ G RG GP G Sbjct: 784 NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGI 843 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSK---GERGAPGPRGSPGPPG 333 + G G G PG PG G G+RG PG G GPPG Sbjct: 844 PGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPG 886 Score = 74.7 bits (182), Expect = 1e-13 Identities = 44/92 (47%), Positives = 50/92 (54%), Gaps = 3/92 (3%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRG 303 +PG GL G GP G PGP+G G G PG PG G GSMG MG P G G Sbjct: 977 MPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036 Query: 304 PVGPPGAPGRDGSKGERGAPG-PRGS-PGPPG 333 G PG PG G +G++G PG G+ PGPPG Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG 1068 Score = 74.3 bits (181), Expect = 2e-13 Identities = 44/102 (43%), Positives = 50/102 (49%), Gaps = 5/102 (4%) Query: 232 YITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS 291 ++ GDK G PG G +G PG PG KG G PG GPPG G GS G G Sbjct: 949 HVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPG-E 1007 Query: 292 PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P L +G G +G G PG G +G G PG G PG PG Sbjct: 1008 PGL----RGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045 Score = 73.9 bits (180), Expect = 2e-13 Identities = 46/109 (42%), Positives = 52/109 (47%), Gaps = 10/109 (9%) Query: 235 GDKVLASNTYLPGPPGLPG-------GQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGS 284 G A + LPG PG PG +GPPG PG GSPG PG+ GP G+PG + Sbjct: 418 GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCT 477 Query: 285 MGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P P P G G G PG G G KG G+PG G PG PG Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPG 526 Score = 73.6 bits (179), Expect = 3e-13 Identities = 52/143 (36%), Positives = 58/143 (40%), Gaps = 38/143 (26%) Query: 222 LPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF-----PGMPGPP 276 +P + ++G + G K PG G PG G G G KG PG+ PG PGP Sbjct: 1013 IPGSMGNMG--MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPT 1070 Query: 277 GQPGPRGSMGPMG----PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS---- 328 G PG G MG G P P G GP GP GAPG GS G G PGP G Sbjct: 1071 GDPGLPGDMGKKGEMGQPGPP------GHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFK 1124 Query: 329 -----------------PGPPGS 334 PG PGS Sbjct: 1125 GIKGLLGPPGIRGPPGLPGFPGS 1147 Score = 70.9 bits (172), Expect = 2e-12 Identities = 44/108 (40%), Positives = 48/108 (44%), Gaps = 20/108 (18%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPD--LSHIKQGRR 302 PGP G PG QG G G G PG PG G G GPRG G G P P I G+ Sbjct: 1179 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1238 Query: 303 GPVGPPGAPGRDGS-----------------KGERGAPGPRGSPGPPG 333 G GPPG+ G G+ KG G PGP+G PG G Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286 Score = 68.6 bits (166), Expect = 1e-11 Identities = 45/119 (37%), Positives = 54/119 (45%), Gaps = 26/119 (21%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGG-----QGPPGSPGPKGSPGFPGMPGPPG 277 P+N DL K GDK PGP GLPG +G PG PG +G PG G+PG PG Sbjct: 251 PDNRTDL-KGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPG 309 Query: 278 QPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFD 336 G +G+ G PG G DG KG++G GP G GP +D Sbjct: 310 SEGVKGNRGF--------------------PGLMGEDGIKGQKGDIGPPGFRGPTEYYD 348 Score = 68.2 bits (165), Expect = 1e-11 Identities = 38/76 (50%), Positives = 41/76 (53%), Gaps = 11/76 (14%) Query: 262 GPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERG 321 G KG G G PGPPG PG +G GP G G +GP G PG PG GSKG RG Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEG--------LPGPQGPKGFPGLPGLTGSKGVRG 94 Query: 322 A---PGPRGSPGPPGS 334 PG GSPG PG+ Sbjct: 95 ISGLPGFSGSPGLPGT 110 Score = 67.8 bits (164), Expect = 2e-11 Identities = 48/126 (38%), Positives = 52/126 (41%), Gaps = 29/126 (23%) Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF----------------PGMPG 274 K I G + A PG PG G G PG PG +G PG PG PG Sbjct: 498 KGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPG 557 Query: 275 PPGQPGPRGSMGPMG-------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRG 327 GQPG +G G G P P G +G GPPG PG GS PGP G Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS------PGPAG 611 Query: 328 SPGPPG 333 GPPG Sbjct: 612 PAGPPG 617 Score = 65.1 bits (157), Expect = 1e-10 Identities = 47/111 (42%), Positives = 53/111 (47%), Gaps = 14/111 (12%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGS--------PGPKGSPGFPGMPGPPGQPGPRGSMG 286 GD L PG PG+ G +G PG PGP G PG PG+ G G PG +G+ G Sbjct: 449 GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508 Query: 287 PMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERG----APGPRGSPGPPG 333 G SP S G G G PGA G G KGE+G G G PG PG Sbjct: 509 LKG-SPG-SPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPG 557 Score = 60.5 bits (145), Expect = 3e-09 Identities = 51/163 (31%), Positives = 57/163 (34%), Gaps = 70/163 (42%) Query: 245 LPGPPGLPGGQGPPGSPG-----------------------PKGSPGFPGMPGPPGQPGP 281 LPGPPG PG GPPG PG KG G G+ GPPG PG Sbjct: 184 LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243 Query: 282 -----------------------RGSMGPMGPS--PDLSHIK----------QGRRGPVG 306 G GP GPS P S+ QG+ G G Sbjct: 244 VIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDG 303 Query: 307 PPGAPGRDGSKGERGAPG------------PRGSPGPPGSFDF 337 PG PG +G KG RG PG G PG G ++ Sbjct: 304 VPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346 Score = 40.4 bits (93), Expect = 0.003 Identities = 18/38 (47%), Positives = 21/38 (55%) Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 G +G G G PG GS G++G GP G PGP G F Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGF 80 Score = 30.4 bits (67), Expect = 3.0 Identities = 14/23 (60%), Positives = 16/23 (69%), Gaps = 3/23 (13%) Query: 314 DGSKGERGA---PGPRGSPGPPG 333 DG+KGE+G PGP GSPG G Sbjct: 42 DGAKGEKGEKGFPGPPGSPGQKG 64 >gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo sapiens] Length = 1670 Score = 97.1 bits (240), Expect = 3e-20 Identities = 48/93 (51%), Positives = 55/93 (59%), Gaps = 11/93 (11%) Query: 247 GPPGLPGGQGP------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300 GPPG+ G G PGSPGP G+PG PGM G PG PGP G++GP GP K G Sbjct: 1340 GPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRG-----KPG 1394 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 + G G PG G G+KG +G PGP GS G PG Sbjct: 1395 KDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPG 1427 Score = 90.9 bits (224), Expect = 2e-18 Identities = 54/124 (43%), Positives = 60/124 (48%), Gaps = 11/124 (8%) Query: 246 PGPPGLPGGQGP------PGSPGPKGSPGFPGMPGP---PGQPGPRGSMGPMGPSPDLSH 296 PG PG PG GP PG G KG GFPG+PG PG PG G G G Sbjct: 105 PGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164 Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQEKV 356 I+ +G G PGAPG G G G PGP G PGPPG F F M R + E+V Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM--GPRGPKGHMGERV 222 Query: 357 FGHR 360 GH+ Sbjct: 223 IGHK 226 Score = 89.4 bits (220), Expect = 5e-18 Identities = 52/111 (46%), Positives = 57/111 (51%), Gaps = 4/111 (3%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282 P A D+G G LPGP G PG QG PG G KG+PGF G GPPG GP+ Sbjct: 1282 PGTAGDMGP--PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339 Query: 283 GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G G L I G GPPG PG G +GE G PGP G+ GP G Sbjct: 1340 GPPGVRGDPGTLKII--SLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCG 1388 Score = 88.2 bits (217), Expect = 1e-17 Identities = 48/104 (46%), Positives = 54/104 (51%), Gaps = 17/104 (16%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI------KQG 300 G PGLPG GP G PGP G PG G PGPPG G G+MGP GP + ++G Sbjct: 171 GDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERG 230 Query: 301 RRGPVGPPGAPG-----------RDGSKGERGAPGPRGSPGPPG 333 +G GPPG PG R KGE+G G G PGPPG Sbjct: 231 VKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274 Score = 86.7 bits (213), Expect = 4e-17 Identities = 45/92 (48%), Positives = 48/92 (52%), Gaps = 4/92 (4%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG GLPG +G G KG G PG PG PG PGP G GP G P QG +G Sbjct: 574 PGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVP 633 Query: 306 GPPGAPGRDGSKGERG----APGPRGSPGPPG 333 G PG PG G +GE PGP G PGPPG Sbjct: 634 GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665 Score = 86.3 bits (212), Expect = 5e-17 Identities = 50/111 (45%), Positives = 54/111 (48%), Gaps = 10/111 (9%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282 P D G + GD PGPPG G GP G+PG GSPG PG PGP G G + Sbjct: 1067 PGPTGDPG--LPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFK 1124 Query: 283 GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G +GP G RGP G PG PG G G RG G G PGP G Sbjct: 1125 GIKGLLGP--------PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAG 1167 Score = 85.9 bits (211), Expect = 6e-17 Identities = 45/97 (46%), Positives = 52/97 (53%), Gaps = 5/97 (5%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG PG QGPPG PG G G PG+PGP G+PG G P P P G +G + Sbjct: 661 PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSL 720 Query: 306 GPPGAPGRDGSKGERGAPGPRGS-----PGPPGSFDF 337 G PG G G G+ G PG +G PG PG+ F Sbjct: 721 GCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGF 757 Score = 85.1 bits (209), Expect = 1e-16 Identities = 51/124 (41%), Positives = 63/124 (50%), Gaps = 15/124 (12%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282 P N LG G+ + PG G PG G PG+PG +GSPG PG+ G G PG + Sbjct: 876 PGNPGILGP--PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAK 933 Query: 283 GSMGPMG-PSP-DLSHI-----KQGRRGPVGPP------GAPGRDGSKGERGAPGPRGSP 329 G G G P P ++SH+ + G +G G P G PG G KG +G PGP G P Sbjct: 934 GEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPP 993 Query: 330 GPPG 333 GP G Sbjct: 994 GPRG 997 Score = 85.1 bits (209), Expect = 1e-16 Identities = 50/115 (43%), Positives = 53/115 (46%), Gaps = 23/115 (20%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG-----------PRGSMGPMG----P 290 PG PGLPG +G G GP+G G G PGPPG PG P GS G G P Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256 Query: 291 SPDLSHI--------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 P SH+ G GP GPPG G G G GAPG G PGP G F Sbjct: 1257 GPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGF 1311 Score = 84.0 bits (206), Expect = 2e-16 Identities = 43/89 (48%), Positives = 46/89 (51%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 L G PG G G PGS G +G+ GFPG G PG PG G G G + G GP Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP 1069 Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG PG G KGE G PGP G GP G Sbjct: 1070 TGDPGLPGDMGKKGEMGQPGPPGHLGPAG 1098 Score = 83.6 bits (205), Expect = 3e-16 Identities = 48/93 (51%), Positives = 53/93 (56%), Gaps = 6/93 (6%) Query: 246 PGPPGLPGGQG---PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--PSPDLSHIKQG 300 PGPPG PG +G P G PGP+G GFPG+PG G G RG G G SP L G Sbjct: 54 PGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPG-TPG 112 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G G PG GSKGE+G PG G+ G PG Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145 Score = 83.2 bits (204), Expect = 4e-16 Identities = 48/112 (42%), Positives = 52/112 (46%), Gaps = 23/112 (20%) Query: 245 LPGPPGLPG--GQGPPGSPGPKGSPGFPG---------------MPGPPGQPGPRGSM-- 285 LPGP G PG G G PG PGPKG GFPG +PG PG PG +G Sbjct: 687 LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAV 746 Query: 286 ----GPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP P G G +G PG PG G+ G G GPRG PG PG Sbjct: 747 AMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG 798 Score = 83.2 bits (204), Expect = 4e-16 Identities = 46/111 (41%), Positives = 57/111 (51%), Gaps = 7/111 (6%) Query: 230 GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289 G ++ G K + PGP G PG G G PG G+PG PG+PGP G PG +G G G Sbjct: 1260 GSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKG 1319 Query: 290 PSPDLSHIKQ-GRRGPVGPPGAPGRDGSKGE------RGAPGPRGSPGPPG 333 + + G GP+GP G PG G G G+PGP G+PG PG Sbjct: 1320 EKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPG 1370 Score = 82.8 bits (203), Expect = 5e-16 Identities = 52/124 (41%), Positives = 60/124 (48%), Gaps = 23/124 (18%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---- 278 P DLG G K L + GPPGLPG G PG G +G G G+PGP G+ Sbjct: 1115 PGPHGDLG--FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGET 1172 Query: 279 ------PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGP---RGSP 329 PGPRG+ G G +G RG G PG PGR G+ G+ G GP G P Sbjct: 1173 GLLRAPPGPRGNPGAQG--------AKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFP 1224 Query: 330 GPPG 333 GPPG Sbjct: 1225 GPPG 1228 Score = 82.8 bits (203), Expect = 5e-16 Identities = 53/111 (47%), Positives = 58/111 (52%), Gaps = 23/111 (20%) Query: 246 PGPPGLPG----GQ-GPPGSPGPKGSPGFPGMPGPPGQ-----PGPRGSMGPMGPS-PDL 294 PGPPGLPG GQ G G PG +GSPG PG PGPPG G +GSMG GP P Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPG 1283 Query: 295 SHIKQGRRGPVGPPGAPGRDGS------------KGERGAPGPRGSPGPPG 333 + G G +G PG PG G KGE+G PG GS GPPG Sbjct: 1284 TAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334 Score = 82.4 bits (202), Expect = 7e-16 Identities = 44/97 (45%), Positives = 49/97 (50%), Gaps = 27/97 (27%) Query: 246 PGPPGLPG--------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI 297 PG PG PG G GP G PG +G+ G PG PGPPG+ GPRG + P P Sbjct: 601 PGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVP----- 655 Query: 298 KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 GP GPPG PG PGP+G PG PGS Sbjct: 656 -----GPPGPPGPPGH---------PGPQGPPGIPGS 678 Score = 82.4 bits (202), Expect = 7e-16 Identities = 47/98 (47%), Positives = 52/98 (53%), Gaps = 15/98 (15%) Query: 239 LASNTYLPGPPGLPGGQGPPGSPGPKGSPGFP---GMPGPPGQPGPRGSMGPMGPSPDLS 295 L+ +T +PGPPG P GPPG PGP+G PG P G G PG PGP G G G Sbjct: 648 LSVSTPVPGPPGPP---GPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG------ 698 Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP GP G G G+KG G PG G PG PG Sbjct: 699 ---IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPG 733 Score = 81.3 bits (199), Expect = 1e-15 Identities = 52/113 (46%), Positives = 57/113 (50%), Gaps = 28/113 (24%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG-----PRGSMGPMGPSPDLSHIK- 298 LPG PGLPG G G GP+G PG PG PG G PG PRG+ G P L+ +K Sbjct: 772 LPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQG----LPGLNGLKG 827 Query: 299 -QGRRGPVGPPGAPG-----RDGSKGERGAPG------------PRGSPGPPG 333 QGRRG GP G PG R G GE G+PG RG PG PG Sbjct: 828 QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPG 880 Score = 80.9 bits (198), Expect = 2e-15 Identities = 51/128 (39%), Positives = 58/128 (45%), Gaps = 38/128 (29%) Query: 244 YLPGPPGLPGG------------------QGPPGSPGPKGSPGFPGMPGPPGQPGPRGSM 285 Y+PGPPGLPG +G PGSPG G PGFPG PG G PG +G Sbjct: 481 YIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEK 540 Query: 286 G----PMG----PSPDLSHIKQGRRGPVGPPGAPG------------RDGSKGERGAPGP 325 G P G P + GR+G G PG PG G KG++G PG Sbjct: 541 GETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGD 600 Query: 326 RGSPGPPG 333 GSPG PG Sbjct: 601 PGSPGSPG 608 Score = 80.1 bits (196), Expect = 3e-15 Identities = 44/95 (46%), Positives = 53/95 (55%), Gaps = 13/95 (13%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 L PPG G G G+ G +G+PGFPG+PG G G G GP G +G GP Sbjct: 1175 LRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTG--------IEGFPGP 1226 Query: 305 VGPPGA--PGRDGSK---GERGAPGPRGSPGPPGS 334 G PGA PG+ G++ G RG+PG G PGPPGS Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261 Score = 79.3 bits (194), Expect = 6e-15 Identities = 47/115 (40%), Positives = 53/115 (46%), Gaps = 26/115 (22%) Query: 245 LPGPPGLPG-----------GQGPPGSPGPKGS------------PGFPGMPGPPGQPGP 281 LPG PGLPG G G PG PG +G+ PG PG PG G GP Sbjct: 731 LPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP 790 Query: 282 RGSMGPMGPSPDL---SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 RG G GP + +G RG G PG G G +G RG GP+G PG PG Sbjct: 791 RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPG 845 Score = 78.6 bits (192), Expect = 1e-14 Identities = 40/88 (45%), Positives = 47/88 (53%), Gaps = 11/88 (12%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G PG+PG QG G G +G PG PG+ GPPG+ G G MG G GP G Sbjct: 856 GSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMG-----------FPGAIGPPG 904 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGS 334 PPG PG G +G G PG +G G PG+ Sbjct: 905 PPGNPGTPGQRGSPGIPGVKGQRGTPGA 932 Score = 78.2 bits (191), Expect = 1e-14 Identities = 43/106 (40%), Positives = 55/106 (51%), Gaps = 1/106 (0%) Query: 230 GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289 G+ +K + L G PG G G PGS G KG+ GFPG+ G G G +G +GP G Sbjct: 280 GESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPG 339 Query: 290 -PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 P + +G G PG PG G++G +G GP G PG PGS Sbjct: 340 FRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385 Score = 77.8 bits (190), Expect = 2e-14 Identities = 46/95 (48%), Positives = 51/95 (53%), Gaps = 16/95 (16%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGF--PGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRR 302 PGP G G QGP G PG GSPG PG+ G PG PG +GS G G P D Sbjct: 362 PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDA-------- 413 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 +G PG+PG GS G G+PGP PGPPG F Sbjct: 414 --MGTPGSPGCAGSPGLPGSPGP---PGPPGDIVF 443 Score = 77.4 bits (189), Expect = 2e-14 Identities = 49/107 (45%), Positives = 52/107 (48%), Gaps = 26/107 (24%) Query: 246 PGPPGLPGGQGP-----------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 PG PGL G +G PGSPG GSPG PG PGPPG PG + GP D Sbjct: 394 PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPG--DIVFRKGPPGD- 450 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERG--------APGPRGSPGPPG 333 G G +G PG PG DG KGE G PGP G PG PG Sbjct: 451 ----HGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493 Score = 77.0 bits (188), Expect = 3e-14 Identities = 48/123 (39%), Positives = 55/123 (44%), Gaps = 33/123 (26%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPG--------FPGMPGPPGQPGPRGSMGPMG------- 289 LPG GL G QG G GPKG PG FPG G PG PG +G MGP+G Sbjct: 819 LPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGN 878 Query: 290 ------PSPDLSHIKQGRRGPVGPPGAPGRDGS------------KGERGAPGPRGSPGP 331 P D G G +GPPG PG G+ KG+RG PG +G G Sbjct: 879 PGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGD 938 Query: 332 PGS 334 G+ Sbjct: 939 KGN 941 Score = 76.6 bits (187), Expect = 4e-14 Identities = 39/84 (46%), Positives = 45/84 (53%), Gaps = 5/84 (5%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG PG G G PGP G PG G GP G+PG G G GP+ + +G +G Sbjct: 1360 PGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGE-----KGNKGSK 1414 Query: 306 GPPGAPGRDGSKGERGAPGPRGSP 329 G PG G DG G +G G GSP Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSGSP 1438 Score = 75.5 bits (184), Expect = 8e-14 Identities = 52/124 (41%), Positives = 57/124 (45%), Gaps = 38/124 (30%) Query: 247 GPPGLPGGQGP---PGSPGPKGS---------PGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 GP GLPG QGP PG PG GS PGF G PG PG PG G G +G P Sbjct: 67 GPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVG-VPGC 125 Query: 295 SHIK-----QGRRGPVGPPGAPGRDGSKGER--------------------GAPGPRGSP 329 S K G G +G PG PG G KG++ GAPGP+G P Sbjct: 126 SGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLP 185 Query: 330 GPPG 333 GPPG Sbjct: 186 GPPG 189 Score = 75.5 bits (184), Expect = 8e-14 Identities = 44/103 (42%), Positives = 49/103 (47%), Gaps = 11/103 (10%) Query: 242 NTYLPGPPGLPGGQGPPGS--------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPD 293 N L GP G PG GPPG GP+G+ G PG+ G GQ G RG GP G Sbjct: 784 NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGI 843 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSK---GERGAPGPRGSPGPPG 333 + G G G PG PG G G+RG PG G GPPG Sbjct: 844 PGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPG 886 Score = 74.7 bits (182), Expect = 1e-13 Identities = 44/92 (47%), Positives = 50/92 (54%), Gaps = 3/92 (3%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRG 303 +PG GL G GP G PGP+G G G PG PG G GSMG MG P G G Sbjct: 977 MPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036 Query: 304 PVGPPGAPGRDGSKGERGAPG-PRGS-PGPPG 333 G PG PG G +G++G PG G+ PGPPG Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG 1068 Score = 74.3 bits (181), Expect = 2e-13 Identities = 44/102 (43%), Positives = 50/102 (49%), Gaps = 5/102 (4%) Query: 232 YITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS 291 ++ GDK G PG G +G PG PG KG G PG GPPG G GS G G Sbjct: 949 HVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPG-E 1007 Query: 292 PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P L +G G +G G PG G +G G PG G PG PG Sbjct: 1008 PGL----RGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045 Score = 73.9 bits (180), Expect = 2e-13 Identities = 46/109 (42%), Positives = 52/109 (47%), Gaps = 10/109 (9%) Query: 235 GDKVLASNTYLPGPPGLPG-------GQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGS 284 G A + LPG PG PG +GPPG PG GSPG PG+ GP G+PG + Sbjct: 418 GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCT 477 Query: 285 MGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P P P G G G PG G G KG G+PG G PG PG Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPG 526 Score = 73.6 bits (179), Expect = 3e-13 Identities = 52/143 (36%), Positives = 58/143 (40%), Gaps = 38/143 (26%) Query: 222 LPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF-----PGMPGPP 276 +P + ++G + G K PG G PG G G G KG PG+ PG PGP Sbjct: 1013 IPGSMGNMG--MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPT 1070 Query: 277 GQPGPRGSMGPMG----PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS---- 328 G PG G MG G P P G GP GP GAPG GS G G PGP G Sbjct: 1071 GDPGLPGDMGKKGEMGQPGPP------GHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFK 1124 Query: 329 -----------------PGPPGS 334 PG PGS Sbjct: 1125 GIKGLLGPPGIRGPPGLPGFPGS 1147 Score = 70.9 bits (172), Expect = 2e-12 Identities = 44/108 (40%), Positives = 48/108 (44%), Gaps = 20/108 (18%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPD--LSHIKQGRR 302 PGP G PG QG G G G PG PG G G GPRG G G P P I G+ Sbjct: 1179 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1238 Query: 303 GPVGPPGAPGRDGS-----------------KGERGAPGPRGSPGPPG 333 G GPPG+ G G+ KG G PGP+G PG G Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286 Score = 68.6 bits (166), Expect = 1e-11 Identities = 45/119 (37%), Positives = 54/119 (45%), Gaps = 26/119 (21%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGG-----QGPPGSPGPKGSPGFPGMPGPPG 277 P+N DL K GDK PGP GLPG +G PG PG +G PG G+PG PG Sbjct: 251 PDNRTDL-KGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPG 309 Query: 278 QPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFD 336 G +G+ G PG G DG KG++G GP G GP +D Sbjct: 310 SEGVKGNRGF--------------------PGLMGEDGIKGQKGDIGPPGFRGPTEYYD 348 Score = 68.2 bits (165), Expect = 1e-11 Identities = 38/76 (50%), Positives = 41/76 (53%), Gaps = 11/76 (14%) Query: 262 GPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERG 321 G KG G G PGPPG PG +G GP G G +GP G PG PG GSKG RG Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEG--------LPGPQGPKGFPGLPGLTGSKGVRG 94 Query: 322 A---PGPRGSPGPPGS 334 PG GSPG PG+ Sbjct: 95 ISGLPGFSGSPGLPGT 110 Score = 67.8 bits (164), Expect = 2e-11 Identities = 48/126 (38%), Positives = 52/126 (41%), Gaps = 29/126 (23%) Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF----------------PGMPG 274 K I G + A PG PG G G PG PG +G PG PG PG Sbjct: 498 KGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPG 557 Query: 275 PPGQPGPRGSMGPMG-------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRG 327 GQPG +G G G P P G +G GPPG PG GS PGP G Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS------PGPAG 611 Query: 328 SPGPPG 333 GPPG Sbjct: 612 PAGPPG 617 Score = 65.1 bits (157), Expect = 1e-10 Identities = 47/111 (42%), Positives = 53/111 (47%), Gaps = 14/111 (12%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGS--------PGPKGSPGFPGMPGPPGQPGPRGSMG 286 GD L PG PG+ G +G PG PGP G PG PG+ G G PG +G+ G Sbjct: 449 GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508 Query: 287 PMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERG----APGPRGSPGPPG 333 G SP S G G G PGA G G KGE+G G G PG PG Sbjct: 509 LKG-SPG-SPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPG 557 Score = 60.5 bits (145), Expect = 3e-09 Identities = 51/163 (31%), Positives = 57/163 (34%), Gaps = 70/163 (42%) Query: 245 LPGPPGLPGGQGPPGSPG-----------------------PKGSPGFPGMPGPPGQPGP 281 LPGPPG PG GPPG PG KG G G+ GPPG PG Sbjct: 184 LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243 Query: 282 -----------------------RGSMGPMGPS--PDLSHIK----------QGRRGPVG 306 G GP GPS P S+ QG+ G G Sbjct: 244 VIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDG 303 Query: 307 PPGAPGRDGSKGERGAPG------------PRGSPGPPGSFDF 337 PG PG +G KG RG PG G PG G ++ Sbjct: 304 VPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346 Score = 40.4 bits (93), Expect = 0.003 Identities = 18/38 (47%), Positives = 21/38 (55%) Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 G +G G G PG GS G++G GP G PGP G F Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGF 80 Score = 30.4 bits (67), Expect = 3.0 Identities = 14/23 (60%), Positives = 16/23 (69%), Gaps = 3/23 (13%) Query: 314 DGSKGERGA---PGPRGSPGPPG 333 DG+KGE+G PGP GSPG G Sbjct: 42 DGAKGEKGEKGFPGPPGSPGQKG 64 >gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] Length = 680 Score = 96.7 bits (239), Expect = 3e-20 Identities = 49/102 (48%), Positives = 54/102 (52%), Gaps = 15/102 (14%) Query: 247 GPPGLPGGQGPPGSPG---------PKGSPGFPGMPGP------PGQPGPRGSMGPMGPS 291 GPPGLPG GP G+ G P+G+PG PG GP PG PG +G G GP Sbjct: 416 GPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPP 475 Query: 292 PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G GP GPPG PG G GE G PGP G PGPPG Sbjct: 476 GPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPG 517 Score = 95.1 bits (235), Expect = 1e-19 Identities = 49/92 (53%), Positives = 55/92 (59%), Gaps = 4/92 (4%) Query: 246 PGPPGLPGGQGP---PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP-DLSHIKQGR 301 PG PGL G +GP PG PG KG G G+PG PG GP G+MGP GP SH G Sbjct: 301 PGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGP 360 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G GP G G G+KGERG+PG G PG PG Sbjct: 361 KGETGPAGPAGYPGAKGERGSPGSDGKPGYPG 392 Score = 93.2 bits (230), Expect = 4e-19 Identities = 51/115 (44%), Positives = 58/115 (50%), Gaps = 27/115 (23%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-------------P 292 PG G PG G PG GPKG+PG PG G PG GP G GP+GP+ P Sbjct: 382 PGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGP 441 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAP--------------GPRGSPGPPG 333 + G RGP+GPPG PG GSKG+ G+P GP G PGPPG Sbjct: 442 RGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPG 496 Score = 91.3 bits (225), Expect = 1e-18 Identities = 51/117 (43%), Positives = 58/117 (49%), Gaps = 28/117 (23%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGF--------PGMPGPPGQ-----------PGPRGSMG 286 PGPPG G +G PG GP G PG+ PG+PGPPG PG G G Sbjct: 62 PGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERG 121 Query: 287 PMGPSPDLSHI-KQGRRGPVGPPG--------APGRDGSKGERGAPGPRGSPGPPGS 334 P GP D+ G RGP GPPG PG+ G +G GAPGPRG PG G+ Sbjct: 122 PYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGA 178 Score = 89.7 bits (221), Expect = 4e-18 Identities = 50/105 (47%), Positives = 56/105 (53%), Gaps = 16/105 (15%) Query: 245 LPGP-----PGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG---PMGPSPDLSH 296 +PGP PG PG QGP G+PGP+G PG G PG PG G +G MG P P Sbjct: 146 IPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLP 205 Query: 297 IKQGRRGPVGPP--------GAPGRDGSKGERGAPGPRGSPGPPG 333 QG GP GPP G PG+ G KG+RG PG G GPPG Sbjct: 206 GPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPG 250 Score = 87.8 bits (216), Expect = 2e-17 Identities = 46/92 (50%), Positives = 50/92 (54%), Gaps = 5/92 (5%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 LPG PGL G G G GPKG PG G+PGP G+ GP G G G + G G Sbjct: 330 LPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERG--SPGSDGK 387 Query: 305 VGPPGAPGRDGSKGERGAPGPRGSP---GPPG 333 G PG PG DG KG G PGP+G P GPPG Sbjct: 388 PGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPG 419 Score = 87.4 bits (215), Expect = 2e-17 Identities = 49/105 (46%), Positives = 52/105 (49%), Gaps = 23/105 (21%) Query: 246 PGPPGLPGGQGP-----------------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPM 288 PG GLPG QGP PG PG KG GFPG GP G PGP+G G Sbjct: 199 PGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGER 258 Query: 289 GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G+ G G PG PG G+KG GAPG G PGPPG Sbjct: 259 GPEGI------GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG 297 Score = 86.7 bits (213), Expect = 4e-17 Identities = 49/100 (49%), Positives = 54/100 (54%), Gaps = 13/100 (13%) Query: 247 GPPGLPGGQGPPGSPGPKG-----SPGFPGMPGPPGQ---PGPRGSMGPMGP----SPDL 294 GP G PG QGPPG GP+G + G PG PG PG PG G GP GP P L Sbjct: 244 GPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGL 303 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 +K G RGP G PG PG G +G G PG G GPPG+ Sbjct: 304 PGLK-GERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGN 342 Score = 85.5 bits (210), Expect = 8e-17 Identities = 49/102 (48%), Positives = 52/102 (50%), Gaps = 14/102 (13%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG PGLPG G G GPKG G G+PGP G PGP G GP G S +QG G Sbjct: 108 PGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAP 167 Query: 306 GP---------PGAPGRDGSKGER-----GAPGPRGSPGPPG 333 GP PG PG +G KGE G PG RG PGP G Sbjct: 168 GPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQG 209 Score = 85.1 bits (209), Expect = 1e-16 Identities = 45/89 (50%), Positives = 48/89 (53%), Gaps = 8/89 (8%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG PGL G +G PG PGPKG PG G PG PG GP G+ G G + G GP Sbjct: 391 PGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHN--------GEAGPR 442 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G PG PG G G G PG GS G PGS Sbjct: 443 GAPGIPGTRGPIGPPGIPGFPGSKGDPGS 471 Score = 84.3 bits (207), Expect = 2e-16 Identities = 50/106 (47%), Positives = 56/106 (52%), Gaps = 8/106 (7%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 G K + + LPGP G G GP G PG KG G PG G PG PG G GP G +P L Sbjct: 347 GPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKG-NPGL 405 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAP------GPRGSPGPPGS 334 K G G GPPG PG G G +G P GPRG+PG PG+ Sbjct: 406 PGPK-GDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGT 450 Score = 80.5 bits (197), Expect = 3e-15 Identities = 46/95 (48%), Positives = 49/95 (51%), Gaps = 14/95 (14%) Query: 253 GGQGPPGSPGPKGSPGFPGMPGPPGQP--------GPRGSMGPMGPS----PDLSHI--K 298 G QG PG PGP G G PG GPPG+P G G GP GPS P + + K Sbjct: 57 GEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGK 116 Query: 299 QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G RGP GP G G G G RG PGP G PGP G Sbjct: 117 PGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAG 151 Score = 80.5 bits (197), Expect = 3e-15 Identities = 47/105 (44%), Positives = 55/105 (52%), Gaps = 17/105 (16%) Query: 246 PGPPGLPGGQGPPGSPG---PKGSPGF--PGMPGP---------PGQPGPRGSMGPMG-- 289 PG PG+PG +G PG+PG P G PGF PG+PG PG PG +G GP G Sbjct: 272 PGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLP 331 Query: 290 PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 P L+ G GP GP G PG G G +G GP G G PG+ Sbjct: 332 GKPGLTG-PPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGA 375 Score = 77.0 bits (188), Expect = 3e-14 Identities = 44/99 (44%), Positives = 48/99 (48%), Gaps = 17/99 (17%) Query: 243 TYLPGPPGLPGGQGPPGSPGPKG--------SPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 T PGP G PG +G PG PG G +PG PG G PG GP G GP G Sbjct: 164 TGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPG----- 218 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G+RG G PG PG G +G G GP G PGP G Sbjct: 219 ----VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQG 253 Score = 49.3 bits (116), Expect = 6e-06 Identities = 32/79 (40%), Positives = 35/79 (44%), Gaps = 16/79 (20%) Query: 246 PGPPG--------LPGGQGPPGSPGPKGS------PGFPGMPGPPGQPGPRGSMGPMGPS 291 PGPPG L G GPPG PGP+G PG PG PGPPGQ G Sbjct: 472 PGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQR 531 Query: 292 PDLS--HIKQGRRGPVGPP 308 P LS + +G G P Sbjct: 532 PSLSGTPLVSANQGVTGMP 550 >gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens] Length = 540 Score = 96.3 bits (238), Expect = 4e-20 Identities = 46/92 (50%), Positives = 56/92 (60%), Gaps = 5/92 (5%) Query: 245 LPGPPGLPGGQGPPGSPG---PKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301 L G PGLPG +G G+PG P+G G G GPPG PGP G+ GP G + +G Sbjct: 152 LDGKPGLPGPKGEKGAPGDFGPRGDQGQDGAAGPPGPPGPPGARGPPGDTG--KDGPRGA 209 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +GP GP G PG+DG G +G PGP+G PG PG Sbjct: 210 QGPAGPKGEPGQDGEMGPKGPPGPKGEPGVPG 241 Score = 89.0 bits (219), Expect = 7e-18 Identities = 43/89 (48%), Positives = 46/89 (51%), Gaps = 11/89 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG PG +GPPG G G G G GP G+PG G MGP GP GP Sbjct: 186 PGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPP-----------GPK 234 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G PG PG+ G G PGP G G PGS Sbjct: 235 GEPGVPGKKGDDGTPSQPGPPGPKGEPGS 263 Score = 87.8 bits (216), Expect = 2e-17 Identities = 50/120 (41%), Positives = 59/120 (49%), Gaps = 7/120 (5%) Query: 221 LLPNNAADLGKYITGDKVLASNTYLPGPPGL---PGGQGPPGSPGPKGSPGFP---GMPG 274 LL L K T + + PGPPG PG +G PG PG G G+P G+ G Sbjct: 95 LLREKLDGLAKIRTAREAPSECVCPPGPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDG 154 Query: 275 PPGQPGPRGSMGPMGP-SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 PG PGP+G G G P + G GP GPPG PG G G+ G GPRG+ GP G Sbjct: 155 KPGLPGPKGEKGAPGDFGPRGDQGQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAG 214 Score = 86.7 bits (213), Expect = 4e-17 Identities = 44/91 (48%), Positives = 49/91 (53%), Gaps = 5/91 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GP G PG +G PG PG KG G P PGPPG G GSMGP G + G GP G Sbjct: 226 GPKGPPGPKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENG-----VDGAPGPKG 280 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 PG G DG+ G RGAPG +G G D+ Sbjct: 281 EPGHRGTDGAAGPRGAPGLKGEQGDTVVIDY 311 Score = 86.3 bits (212), Expect = 5e-17 Identities = 48/105 (45%), Positives = 54/105 (51%), Gaps = 18/105 (17%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 L GPPG G GPPG PG KG G PG PG G+ GP+G G G P + +K G G Sbjct: 319 LKGPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPG-EPGPAGLK-GEAGE 376 Query: 305 VGPPGAPGRDGSKGERG----------------APGPRGSPGPPG 333 +G G PG DG KGE+G PGP G PGPPG Sbjct: 377 MGLSGLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPGPPG 421 Score = 84.0 bits (206), Expect = 2e-16 Identities = 48/115 (41%), Positives = 56/115 (48%), Gaps = 27/115 (23%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLS-------- 295 P PG PG +G PGS GP+G G G PGP G+PG RG+ G GP +P L Sbjct: 249 PSQPGPPGPKGEPGSMGPRGENGVDGAPGPKGEPGHRGTDGAAGPRGAPGLKGEQGDTVV 308 Query: 296 --------HIKQGRRGPVGPPGAPGRDGSKGERGAP---------GPRGSPGPPG 333 +G GP GPPG PG G+KGE G P GP+G G PG Sbjct: 309 IDYDGRILDALKGPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPG 363 Score = 79.0 bits (193), Expect = 7e-15 Identities = 48/109 (44%), Positives = 53/109 (48%), Gaps = 23/109 (21%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG PG G G GPKG G G G G+ GP G GP+GP P L + G +G Sbjct: 414 PGPPGPPGPMGLQGIQGPKGLDGAKGEKGASGERGPSGLPGPVGP-PGLIGL-PGTKGEK 471 Query: 306 GPPGAPGRD---------------GSKGERGAP------GPRGSPGPPG 333 G PG PG D G KGERG P G +G PGPPG Sbjct: 472 GRPGEPGLDGFPGPRGEKGDRSERGEKGERGVPGRKGVKGQKGEPGPPG 520 Score = 77.8 bits (190), Expect = 2e-14 Identities = 41/81 (50%), Positives = 47/81 (58%), Gaps = 8/81 (9%) Query: 257 PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGS 316 PPG PG +G PG G PGPPGQ G G GP+G K G GP G GAPG G Sbjct: 119 PPGPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDG-----KPGLPGPKGEKGAPGDFGP 173 Query: 317 KGERG---APGPRGSPGPPGS 334 +G++G A GP G PGPPG+ Sbjct: 174 RGDQGQDGAAGPPGPPGPPGA 194 Score = 77.4 bits (189), Expect = 2e-14 Identities = 51/126 (40%), Positives = 58/126 (46%), Gaps = 38/126 (30%) Query: 246 PGPPGLPGGQGP---PGSPG------PKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLS 295 PGPPG+PG +G PG+PG PKG G PG PGP G G G MG G P D Sbjct: 329 PGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGPAGLKGEAGEMGLSGLPGADGL 388 Query: 296 HIKQGRR----------------GPVGPPGAP------------GRDGSKGERGAPGPRG 327 ++G GP GPPG P G DG+KGE+GA G RG Sbjct: 389 KGEKGESASDSLQESLAQLIVEPGPPGPPGPPGPMGLQGIQGPKGLDGAKGEKGASGERG 448 Query: 328 SPGPPG 333 G PG Sbjct: 449 PSGLPG 454 Score = 76.6 bits (187), Expect = 4e-14 Identities = 42/88 (47%), Positives = 45/88 (51%), Gaps = 14/88 (15%) Query: 247 GPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303 GP GLPG GPPG PG KG G PG PG G PGPRG G + RG Sbjct: 448 GPSGLPGPVGPPGLIGLPGTKGEKGRPGEPGLDGFPGPRGEKG-----------DRSERG 496 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGP 331 G G PGR G KG++G PGP G P Sbjct: 497 EKGERGVPGRKGVKGQKGEPGPPGLDQP 524 Score = 70.1 bits (170), Expect = 3e-12 Identities = 50/137 (36%), Positives = 54/137 (39%), Gaps = 37/137 (27%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF----------------------- 269 I G+K PG PG G +G G G G PG Sbjct: 349 IDGEKGPKGQKGDPGEPGPAGLKGEAGEMGLSGLPGADGLKGEKGESASDSLQESLAQLI 408 Query: 270 --PGMPGPPGQPGPRGSMGPMGPSPDLSHIK-----------QGRRGPVGPPGAPGRDGS 316 PG PGPPG PGP G G GP L K G GPVGPPG G G+ Sbjct: 409 VEPGPPGPPGPPGPMGLQGIQGPK-GLDGAKGEKGASGERGPSGLPGPVGPPGLIGLPGT 467 Query: 317 KGERGAPGPRGSPGPPG 333 KGE+G PG G G PG Sbjct: 468 KGEKGRPGEPGLDGFPG 484 Score = 53.5 bits (127), Expect = 3e-07 Identities = 30/67 (44%), Positives = 32/67 (47%), Gaps = 20/67 (29%) Query: 275 PPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKG------ERGAPGPRGS 328 PPG PG RG K GRRG GPPG GRDG G + G PGP+G Sbjct: 119 PPGPPGRRG--------------KPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGE 164 Query: 329 PGPPGSF 335 G PG F Sbjct: 165 KGAPGDF 171 Score = 42.4 bits (98), Expect = 8e-04 Identities = 20/48 (41%), Positives = 24/48 (50%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPD 293 PGP G G + G G +G PG G+ G G+PGP G P PD Sbjct: 483 PGPRGEKGDRSERGEKGERGVPGRKGVKGQKGEPGPPGLDQPCPVGPD 530 Score = 40.8 bits (94), Expect = 0.002 Identities = 28/72 (38%), Positives = 28/72 (38%), Gaps = 18/72 (25%) Query: 246 PGPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299 PG PGL G GP G G KG G PG G GQ G G G P Sbjct: 474 PGEPGLDGFPGPRGEKGDRSERGEKGERGVPGRKGVKGQKGEPGPPGLDQPC-------- 525 Query: 300 GRRGPVGPPGAP 311 PVGP G P Sbjct: 526 ----PVGPDGLP 533 Score = 30.4 bits (67), Expect = 3.0 Identities = 19/49 (38%), Positives = 22/49 (44%), Gaps = 2/49 (4%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF--PGMPGPPGQPGP 281 G+K S G G+PG +G G G G PG P GP G P P Sbjct: 487 GEKGDRSERGEKGERGVPGRKGVKGQKGEPGPPGLDQPCPVGPDGLPVP 535 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 95.9 bits (237), Expect = 6e-20 Identities = 48/90 (53%), Positives = 53/90 (58%), Gaps = 5/90 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303 G G PG +GPPG GPKGSPG FPG PGPPG+PGP G GP G D + G+ G Sbjct: 1318 GAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDG--EPGQTG 1375 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G PG G G+RG PGP G G G Sbjct: 1376 SPGPTGEPGPSGPPGKRGPPGPAGPEGRQG 1405 Score = 95.5 bits (236), Expect = 8e-20 Identities = 47/89 (52%), Positives = 50/89 (56%), Gaps = 1/89 (1%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGP 304 PGP G PG GPPG PGP G G PG G G+PG GS GP G P P K+G GP Sbjct: 1338 PGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGP 1397 Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G G G+KGE G GP G GP G Sbjct: 1398 AGPEGRQGEKGAKGEAGLEGPPGKTGPIG 1426 Score = 94.7 bits (234), Expect = 1e-19 Identities = 52/113 (46%), Positives = 60/113 (53%), Gaps = 15/113 (13%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP------PGQPGPRGSMGPM 288 G+K L GPPG G GP G+PG G G G+PGP PG PGP G GPM Sbjct: 1405 GEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPM 1464 Query: 289 GPSPDLSHIK--------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP P L +K +G G +G G PG G KG+RG PGP+GS GP G Sbjct: 1465 GP-PGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKG 1516 Score = 93.6 bits (231), Expect = 3e-19 Identities = 51/112 (45%), Positives = 57/112 (50%), Gaps = 25/112 (22%) Query: 247 GPPG------LPGGQGPPGSPGPKGSPGFPGMPGP---------PGQPGPRGSMGPMGPS 291 GPPG +PG G PG GPKGS GFPG PG PG+PGPRG GP GP Sbjct: 859 GPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPR 918 Query: 292 PDLS----------HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 + G GP GPPG G +G +G G PGP+G PGPPG Sbjct: 919 GERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPG 970 Score = 93.6 bits (231), Expect = 3e-19 Identities = 47/100 (47%), Positives = 54/100 (54%), Gaps = 11/100 (11%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 G+ T PGPPG+ G QGP G GP G G PG PGPPG+ G G G Sbjct: 982 GETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAG-------- 1033 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 K+G +G GP G PG+DG G RG PG RG PGP G+ Sbjct: 1034 ---KEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGA 1070 Score = 92.4 bits (228), Expect = 6e-19 Identities = 52/108 (48%), Positives = 57/108 (52%), Gaps = 19/108 (17%) Query: 246 PGPPGLPG--GQ-GPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP-SPDLSHIKQGR 301 PGPPG PG GQ GPPG G G PG G PGP G+PGP G G GP P +QG Sbjct: 1347 PGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGE 1406 Query: 302 RG---------------PVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 +G P+GP GAPG+ G G RG PGP G G PGS Sbjct: 1407 KGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGS 1454 Score = 91.3 bits (225), Expect = 1e-18 Identities = 53/111 (47%), Positives = 56/111 (50%), Gaps = 22/111 (19%) Query: 245 LPGPPG---LPGGQGPPGSPGPKGSPG------------FPGMPGPPGQPGPR------G 283 LPGP G L G +GPPG PGP GSPG PG PGP G PGP G Sbjct: 1064 LPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPG 1123 Query: 284 SMGPMGPS-PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP GP+ D G GP GP G PG DG KGE G PG +GS G G Sbjct: 1124 EKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKG 1174 Score = 90.9 bits (224), Expect = 2e-18 Identities = 45/98 (45%), Positives = 51/98 (52%), Gaps = 10/98 (10%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----------PSPDLS 295 PGP GL G +GPPG PGP G G G PGP G GP+G GP G P P + Sbjct: 678 PGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGA 737 Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G +GP+G PG PG G+ G G PG G PG G Sbjct: 738 IGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKG 775 Score = 90.9 bits (224), Expect = 2e-18 Identities = 44/88 (50%), Positives = 51/88 (57%), Gaps = 1/88 (1%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305 GPPG G +G G GP G+ G PG GPPG GP+GS GP+G P + G G Sbjct: 1300 GPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQD 1359 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPG G DG G+ G+PGP G PGP G Sbjct: 1360 GPPGDKGDDGEPGQTGSPGPTGEPGPSG 1387 Score = 90.5 bits (223), Expect = 2e-18 Identities = 49/105 (46%), Positives = 54/105 (51%), Gaps = 17/105 (16%) Query: 235 GDKVLASNTYLPGPPGL---PGGQGPPGSPGPKGSPGFPGMPGP---PGQPGPRGSMGPM 288 GD+ LPG G PG GPPG PG G G G GP PG+PGPRG +GP Sbjct: 628 GDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPK 687 Query: 289 GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP GP GPPG G DG G +G GP+G PGPPG Sbjct: 688 GPP-----------GPPGPPGVTGMDGQPGPKGNVGPQGEPGPPG 721 Score = 90.5 bits (223), Expect = 2e-18 Identities = 54/113 (47%), Positives = 57/113 (50%), Gaps = 25/113 (22%) Query: 246 PGPPGLPGGQGPPGS---------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296 PGP GLPG GPPG PGP G+ G G GPPG PGP GS G GP+ Sbjct: 1041 PGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGP 1100 Query: 297 IK-QGRRGPVGPP------GAP---------GRDGSKGERGAPGPRGSPGPPG 333 I GR GP GPP GAP GRDG +G G PGP G GPPG Sbjct: 1101 IGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPG 1153 Score = 89.7 bits (221), Expect = 4e-18 Identities = 46/88 (52%), Positives = 47/88 (53%), Gaps = 11/88 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG G G QGP G PGPKG PG PG G PG PG RG G QG+ GP Sbjct: 945 PGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETG-----------FQGKTGPP 993 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPG G G GE G G RG PGPPG Sbjct: 994 GPPGVVGPQGPTGETGPMGERGHPGPPG 1021 Score = 89.0 bits (219), Expect = 7e-18 Identities = 45/88 (51%), Positives = 47/88 (53%), Gaps = 11/88 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PGPPG G QG PG PG KG G G GPPG PGPRG G G GP Sbjct: 1221 PGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGAD-----------GPQ 1269 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPPG G G+ GE+G PG G PG PG Sbjct: 1270 GPPGGIGNPGAVGEKGEPGEAGEPGLPG 1297 Score = 89.0 bits (219), Expect = 7e-18 Identities = 50/111 (45%), Positives = 55/111 (49%), Gaps = 29/111 (26%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---------PGPRGSMGPMGPSPDLSHI 297 GPPGLPG +G G G KG PG G+ GPPG+ PGP+GS GP G Sbjct: 1465 GPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGIT--- 1521 Query: 298 KQGRRGPVGPPGAPGRDGS---------------KGERGAPGPRGSPGPPG 333 G GP+GPPG PG G KGE G PGP G PGPPG Sbjct: 1522 --GPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570 Score = 88.2 bits (217), Expect = 1e-17 Identities = 47/93 (50%), Positives = 48/93 (51%), Gaps = 14/93 (15%) Query: 247 GPPGLPGGQGPPGS------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300 GP G PGG G PG+ PG G PG PG GPPG G RG G GPS G Sbjct: 1267 GPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPS--------G 1318 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP GP G PG DG KG G G G PGPPG Sbjct: 1319 AAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPG 1351 Score = 87.4 bits (215), Expect = 2e-17 Identities = 46/98 (46%), Positives = 52/98 (53%), Gaps = 10/98 (10%) Query: 246 PGPPGLPG---------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLS 295 PGP G PG +G PG GPKG GF G+ G PG+ G RG GP G P P Sbjct: 600 PGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGD 659 Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 ++G G VGP G PG G +G G GP G PGPPG Sbjct: 660 DGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPG 697 Score = 87.4 bits (215), Expect = 2e-17 Identities = 47/102 (46%), Positives = 56/102 (54%), Gaps = 13/102 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---------PGPRGSMGPMGPSPDLSH 296 PGPPG PG G G PGPKG+ G G PGPPGQ PGP+G++GP G L Sbjct: 690 PGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGK 749 Query: 297 IK-QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 G G GPPG PG++G GE+G +G PGP G + Sbjct: 750 PGLPGMPGADGPPGHPGKEGPPGEKGG---QGPPGPQGPIGY 788 Score = 85.5 bits (210), Expect = 8e-17 Identities = 45/94 (47%), Positives = 53/94 (56%), Gaps = 8/94 (8%) Query: 243 TYLPGPPGLPGGQGPPGSPGP---KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299 T + G PG G GP G PGP +G+PG G+PGP G GP G GP+G P L Sbjct: 699 TGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLG-KPGL----P 753 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G GPPG PG++G GE+G GP G GP G Sbjct: 754 GMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIG 787 Score = 85.1 bits (209), Expect = 1e-16 Identities = 47/110 (42%), Positives = 53/110 (48%), Gaps = 22/110 (20%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSMGPMG---------- 289 PG PG+PG GPPG PG +G PG G GPPG PGPRG G G Sbjct: 750 PGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGE 809 Query: 290 ------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P +G RG +GPPG G DG +G +G GP G PGP G Sbjct: 810 KGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLG 859 Score = 84.7 bits (208), Expect = 1e-16 Identities = 44/90 (48%), Positives = 49/90 (54%), Gaps = 1/90 (1%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ-GRRG 303 L GP GLPG GP G PG G G G PG G G +G GP GP+ I Q G G Sbjct: 1136 LQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSG 1195 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG G+ G G++G GPRG PGPPG Sbjct: 1196 ADGEPGPRGQQGLFGQKGDEGPRGFPGPPG 1225 Score = 84.3 bits (207), Expect = 2e-16 Identities = 50/125 (40%), Positives = 57/125 (45%), Gaps = 38/125 (30%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSM----------------GPM 288 LPGPPG G G G PG +G PG PG+PG G PGP G+M GPM Sbjct: 479 LPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPM 538 Query: 289 --------------------GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS 328 GP+ + GR GPVGPPG+ G G G+ G GPRG Sbjct: 539 VSAQESQAQAILQQARLALRGPAGPMG--LTGRPGPVGPPGSGGLKGEPGDVGPQGPRGV 596 Query: 329 PGPPG 333 GPPG Sbjct: 597 QGPPG 601 Score = 84.3 bits (207), Expect = 2e-16 Identities = 47/95 (49%), Positives = 51/95 (53%), Gaps = 13/95 (13%) Query: 246 PGPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIK 298 PGP G PG +GPPG GP KG+ G G+ GPPG+ GP G G G P PD Sbjct: 1383 PGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPD----- 1437 Query: 299 QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G RG GP G G GS G G PGP G PG PG Sbjct: 1438 -GLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPG 1471 Score = 83.6 bits (205), Expect = 3e-16 Identities = 45/95 (47%), Positives = 53/95 (55%), Gaps = 8/95 (8%) Query: 245 LPGPPGLPG-----GQ-GPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIK 298 LPGPPG G GQ GPPG PGP+G G PG GP G PG G+ G +G + + Sbjct: 1232 LPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPG--E 1289 Query: 299 QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G G G PG G +GE+G GP G+ GPPG Sbjct: 1290 AGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPG 1324 Score = 82.8 bits (203), Expect = 5e-16 Identities = 47/100 (47%), Positives = 49/100 (49%), Gaps = 1/100 (1%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 GDK G G G QGPPG GP+G G PG G G+PGPRG G G D Sbjct: 1156 GDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDE 1215 Query: 295 S-HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GPVG G PG G KGE G G G PGPPG Sbjct: 1216 GPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPG 1255 Score = 80.5 bits (197), Expect = 3e-15 Identities = 49/107 (45%), Positives = 52/107 (48%), Gaps = 23/107 (21%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 L GP G G G PG GP GS G G PG G GPRG GP GP+ K GRRG Sbjct: 557 LRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAG-----KPGRRGR 611 Query: 305 VGPPGA---PGRDGSKGE---------------RGAPGPRGSPGPPG 333 G GA PG+ G KG+ RG PGP G PGPPG Sbjct: 612 AGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPG 658 Score = 80.5 bits (197), Expect = 3e-15 Identities = 41/88 (46%), Positives = 50/88 (56%), Gaps = 2/88 (2%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GPPG PG G G G G G PG PGP G GP+G GP GP P ++ + G+ GP G Sbjct: 652 GPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGP-PGVTGM-DGQPGPKG 709 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G G G G++G PG +G PGP G+ Sbjct: 710 NVGPQGEPGPPGQQGNPGAQGLPGPQGA 737 Score = 80.1 bits (196), Expect = 3e-15 Identities = 44/103 (42%), Positives = 48/103 (46%), Gaps = 26/103 (25%) Query: 246 PGPPGLPGGQG---------------PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP 290 PGPPG PG QG P G PG G PG G PG G PGP G++G Sbjct: 1017 PGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALG---- 1072 Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G GP GPPG G G +G GA GP G PG PG Sbjct: 1073 -------LKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPG 1108 Score = 79.7 bits (195), Expect = 4e-15 Identities = 43/95 (45%), Positives = 49/95 (51%), Gaps = 7/95 (7%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----PSPDLSHIKQGR 301 PGP G G QG PG PG +G+PG G+PGP G GP G GP+G P + G Sbjct: 705 PGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGH 764 Query: 302 RGPVGPPGAPGRDGSKGERGA---PGPRGSPGPPG 333 G GPPG G G G +G PGPRG G G Sbjct: 765 PGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADG 799 Score = 79.3 bits (194), Expect = 6e-15 Identities = 45/101 (44%), Positives = 51/101 (50%), Gaps = 13/101 (12%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGM------------PGPPGQPGPRGSMGPMG-PSPD 293 GPPG G QGP G PGP G+ G PG GP G PGP G +G G P P Sbjct: 1177 GPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPP 1236 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 + G G +GPPG PG G G GA GP+G PG G+ Sbjct: 1237 GEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGN 1277 Score = 78.2 bits (191), Expect = 1e-14 Identities = 42/93 (45%), Positives = 49/93 (52%), Gaps = 14/93 (15%) Query: 247 GPPGLPGGQGPPGSPGPKGSPG------FPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300 GP G G GP G PGP G PG PG+PG PG+ GP+GS+G G G Sbjct: 841 GPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPG--------FPG 892 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G G PG+ G +G+RG GPRG GP G Sbjct: 893 ANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRG 925 Score = 77.4 bits (189), Expect = 2e-14 Identities = 47/119 (39%), Positives = 50/119 (42%), Gaps = 28/119 (23%) Query: 247 GPPGLPGGQGPPGSPGP------------------------KGSPGFPGMPGPPGQPGPR 282 GPPG GGQGPPG GP KG GFPG G G G R Sbjct: 769 GPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDR 828 Query: 283 GSMGPMGP----SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 G +GP GP P+ + G G GP G PG G G G PG G GP GS F Sbjct: 829 GEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGF 887 Score = 75.5 bits (184), Expect = 8e-14 Identities = 49/114 (42%), Positives = 58/114 (50%), Gaps = 16/114 (14%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282 P D+G I GD+ G G PG +G G GPKG G G PGP G PG + Sbjct: 816 PGFKGDMG--IKGDR---------GEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEK 864 Query: 283 GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGA---PGPRGSPGPPG 333 G +G G P +QG +G +G PG PG +G KG RG PGPRG GP G Sbjct: 865 GKLGVPG-LPGYPG-RQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTG 916 Score = 72.4 bits (176), Expect = 7e-13 Identities = 36/71 (50%), Positives = 40/71 (56%), Gaps = 8/71 (11%) Query: 245 LPGPPGLPGGQGPPGSPGPKGS---PGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301 LPGP G G +G G GP G PG PG+PGPPG G +GS GP GP + H Sbjct: 1505 LPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGH----- 1559 Query: 302 RGPVGPPGAPG 312 GP GPPG PG Sbjct: 1560 PGPPGPPGPPG 1570 Score = 67.0 bits (162), Expect = 3e-11 Identities = 41/98 (41%), Positives = 43/98 (43%), Gaps = 23/98 (23%) Query: 249 PGLPGGQ--------GPPGSPGPKGSPGF--PGM--PGPPGQPGPRGSMGPMGPSPDLSH 296 PG+P Q GP G G KG P PGM GPPG GP G GP Sbjct: 432 PGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGP--------- 482 Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G GP G G PG G G G PG G PGPPG+ Sbjct: 483 --PGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGT 518 Score = 55.8 bits (133), Expect = 7e-08 Identities = 26/43 (60%), Positives = 27/43 (62%), Gaps = 3/43 (6%) Query: 246 PGPPGLPGGQGPPG---SPGPKGSPGFPGMPGPPGQPGPRGSM 285 PGPPGLPG GP G S GP G G G PGPPG PGP G + Sbjct: 1530 PGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEV 1572 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 95.9 bits (237), Expect = 6e-20 Identities = 50/104 (48%), Positives = 56/104 (53%), Gaps = 15/104 (14%) Query: 245 LPGPPGLPGGQGPPGSPGPK--------GSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296 LPG PG PG QGP G PG K G+PG PG PG PG+ GPRG G +GP D Sbjct: 1425 LPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGF 1484 Query: 297 I-------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 ++G RGP GP G+ G G G GA GP G PGP G Sbjct: 1485 PGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTG 1528 Score = 90.9 bits (224), Expect = 2e-18 Identities = 45/87 (51%), Positives = 50/87 (57%), Gaps = 8/87 (9%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GP GL G GPPG GP G G PG PGPPG GPRG G +G ++G GP G Sbjct: 1595 GPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVG--------EKGDEGPPG 1646 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 PG PG+ G +G RGAPG RG G G Sbjct: 1647 DPGLPGKAGERGLRGAPGVRGPVGEKG 1673 Score = 90.9 bits (224), Expect = 2e-18 Identities = 47/89 (52%), Positives = 52/89 (58%), Gaps = 4/89 (4%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG-PMGPSPDLSHIKQGRRGP 304 PG GLPG +G G PGP G PG PG PG G+PG G G P P D ++G +G Sbjct: 1805 PGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGED---GRKGEKGD 1861 Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G GRDG KGERGAPG G GPPG Sbjct: 1862 SGASGREGRDGPKGERGAPGILGPQGPPG 1890 Score = 89.0 bits (219), Expect = 7e-18 Identities = 51/107 (47%), Positives = 56/107 (52%), Gaps = 20/107 (18%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGM------------PGPPGQPGPRGSMGPMGPSP 292 LPG G PG QGPPGS KG GFPG PG PG PG +GS G GP Sbjct: 1276 LPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRG 1335 Query: 293 DLSHIKQGRRGPVGPPGAPGR------DGSKGERGAPGPRGSPGPPG 333 D ++G RGP G PGAPG+ G G +G PGP G PGP G Sbjct: 1336 DPG--ERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRG 1380 Score = 89.0 bits (219), Expect = 7e-18 Identities = 45/90 (50%), Positives = 50/90 (55%), Gaps = 1/90 (1%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG-PMGPSPDLSHIKQGRRGP 304 PG PG G G PG+PG KGSPG PG G PG+ GPRG G P P + G G Sbjct: 1307 PGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGR 1366 Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G PG G G +G G PGPRG PG PG+ Sbjct: 1367 KGDPGPSGPPGPRGPLGDPGPRGPPGLPGT 1396 Score = 88.6 bits (218), Expect = 9e-18 Identities = 51/103 (49%), Positives = 56/103 (54%), Gaps = 22/103 (21%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ--------------PGPRGSMGPMGPS 291 PGPPG PG GP G GP G G PG GPPG+ PGP G +GP G S Sbjct: 2185 PGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQG-S 2243 Query: 292 PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 P L G+ G G PGAPGRDG+ G+ G RGSPG PGS Sbjct: 2244 PGLP----GQVGETGKPGAPGRDGASGK---DGDRGSPGVPGS 2279 Score = 88.2 bits (217), Expect = 1e-17 Identities = 46/99 (46%), Positives = 50/99 (50%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 G+ L + GP G PG QGP G PGP G G PG PG PG GP G GP G + Sbjct: 2150 GNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEP 2209 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 RG GP GA G G G G GP+GSPG PG Sbjct: 2210 GETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPG 2248 Score = 87.8 bits (216), Expect = 2e-17 Identities = 45/92 (48%), Positives = 52/92 (56%), Gaps = 6/92 (6%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-----PDLSHIKQ 299 LPG PG PG QGP G PG G G G PGP G+ G +G GP GP+ P ++ + Sbjct: 1457 LPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAG-RP 1515 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGP 331 G +GP GPPG GR G KGE G PG GP Sbjct: 1516 GAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGP 1547 Score = 87.0 bits (214), Expect = 3e-17 Identities = 45/117 (38%), Positives = 55/117 (47%), Gaps = 29/117 (24%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPG-----------------------------MPGPP 276 PGP G PG +GP G PGP+G PG PG +PG P Sbjct: 1370 PGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLP 1429 Query: 277 GQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PGP+G +GP G + + G G G PG+PG G +G GA GP+G G PG Sbjct: 1430 GSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPG 1486 Score = 86.3 bits (212), Expect = 5e-17 Identities = 51/119 (42%), Positives = 57/119 (47%), Gaps = 13/119 (10%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGP--------PGSPGPKGSPGFPGMPG 274 P + A +G + G K + GP G G QG PG PGPKG PG G G Sbjct: 1539 PGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIG 1598 Query: 275 PPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G+ GP G GP G D GR GP GP G GRDG GE+G GP G PG PG Sbjct: 1599 LTGRAGPPGDSGPPGEKGD-----PGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPG 1652 Score = 85.9 bits (211), Expect = 6e-17 Identities = 52/127 (40%), Positives = 59/127 (46%), Gaps = 42/127 (33%) Query: 250 GLPGGQGPPGSPGPKGSPGFPGMPGPPG------QPGPRGSMGPMGPSPDLSHI----KQ 299 G+PG GPPG PG KG G PG+PG PG Q GPRG MG GPS + ++ Sbjct: 2374 GVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGRE 2433 Query: 300 GRRGPVGPPGAPGR--------------------DGSKGERGAPG------------PRG 327 G GP+GPPG PG G +GERG PG PRG Sbjct: 2434 GIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRG 2493 Query: 328 SPGPPGS 334 GPPGS Sbjct: 2494 LTGPPGS 2500 Score = 84.7 bits (208), Expect = 1e-16 Identities = 44/91 (48%), Positives = 49/91 (53%), Gaps = 11/91 (12%) Query: 247 GPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303 GPPGL G +G PGS GPKG G PG+ G G+PGPRG G G G RG Sbjct: 2108 GPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPG--------LPGERG 2159 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 GP G PG G +G G G G PGPPG+ Sbjct: 2160 MAGPEGKPGLQGPRGPPGPVGGHGDPGPPGA 2190 Score = 84.3 bits (207), Expect = 2e-16 Identities = 48/117 (41%), Positives = 55/117 (47%), Gaps = 18/117 (15%) Query: 235 GDKVLASNTYLPGPPGLPG---GQGPPGSPGPKGS---------------PGFPGMPGPP 276 G LA PG PGLPG G G G PG +G PG PG PGPP Sbjct: 2028 GPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPP 2087 Query: 277 GQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PGP+ S+ GP G +G G PG+ G G KG+RG PG +G G PG Sbjct: 2088 GPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPG 2144 Score = 81.6 bits (200), Expect = 1e-15 Identities = 52/125 (41%), Positives = 59/125 (47%), Gaps = 43/125 (34%) Query: 247 GPPGLPGGQGPP------GSPGPKGSPGFPGMPGP------------------------- 275 G PGL G +GPP G PGP G+PG G GP Sbjct: 2165 GKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTG 2224 Query: 276 ----PGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSK---GERGAPGPRGS 328 PG PGP G +GP G SP L G+ G G PGAPGRDG+ G+RG+PG GS Sbjct: 2225 AVGLPGPPGPSGLVGPQG-SPGL----PGQVGETGKPGAPGRDGASGKDGDRGSPGVPGS 2279 Query: 329 PGPPG 333 PG PG Sbjct: 2280 PGLPG 2284 Score = 81.6 bits (200), Expect = 1e-15 Identities = 44/93 (47%), Positives = 52/93 (55%), Gaps = 7/93 (7%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP- 304 PGP G G +G G+PG G PG G G G PGP GS+GP G P+ ++G RGP Sbjct: 2691 PGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRG--PEGLQGQKGERGPP 2748 Query: 305 ----VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 VG PG PG G +GE+G PGP G G G Sbjct: 2749 GERVVGAPGVPGAPGERGEQGRPGPAGPRGEKG 2781 Score = 81.3 bits (199), Expect = 1e-15 Identities = 47/100 (47%), Positives = 52/100 (52%), Gaps = 12/100 (12%) Query: 247 GPPGLPGGQGPPGSPG---PKGSPGFPGMPGPPGQPGPRGSMGPMG----PSPDLSHIKQ 299 G PG+PG G PG G PKG GF G PGP G G +G G G P P + Sbjct: 2662 GEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSA 2721 Query: 300 GRRGP---VGPPGAPGRDGSKGERGAPGPR--GSPGPPGS 334 G GP VGP G G G KGERG PG R G+PG PG+ Sbjct: 2722 GPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGA 2761 Score = 80.9 bits (198), Expect = 2e-15 Identities = 43/99 (43%), Positives = 50/99 (50%), Gaps = 12/99 (12%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-----------PDL 294 PGP G PG +GP G G +G PG G G G+PG G GP G + P L Sbjct: 1754 PGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGL 1813 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +QG GP GPPG PG+ G G+ G G G PG PG Sbjct: 1814 RG-EQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPG 1851 Score = 80.5 bits (197), Expect = 3e-15 Identities = 49/103 (47%), Positives = 53/103 (51%), Gaps = 16/103 (15%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLS-----HIKQ 299 GP G G G PG+PG +G GF G PGP G PG RG G G P L K Sbjct: 1728 GPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKP 1787 Query: 300 GRRGPVGPPGA------PGRD---GSKGERGAPGPRGSPGPPG 333 G GP GP GA PGRD G +GE+G PGP G PG PG Sbjct: 1788 GAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPG 1830 Score = 80.5 bits (197), Expect = 3e-15 Identities = 48/115 (41%), Positives = 58/115 (50%), Gaps = 22/115 (19%) Query: 240 ASNTYLP------GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR-------GSMG 286 +S ++LP GP G G QGPPG GP G PG G+ G G PGP+ G G Sbjct: 1966 SSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERG 2025 Query: 287 PMGPS--------PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P GPS P + + GR G VG G PG G +GE+G G +G GPPG Sbjct: 2026 PPGPSGLAGEPGKPGIPGL-PGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPG 2079 Score = 80.5 bits (197), Expect = 3e-15 Identities = 46/103 (44%), Positives = 52/103 (50%), Gaps = 6/103 (5%) Query: 235 GDKVLASNTYLPGPPGLPG-GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPD 293 G++ L + PGP G PG G G PGP G G PG PG PG PG G +G G + Sbjct: 2000 GERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGE 2059 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFD 336 +G RG G G GRDG G G PGP G PGP S D Sbjct: 2060 -----RGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVD 2097 Score = 79.7 bits (195), Expect = 4e-15 Identities = 48/109 (44%), Positives = 54/109 (49%), Gaps = 13/109 (11%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 GDK A LPG GL G QG PG+ G G PG PG G PG G +G +G MGP Sbjct: 2569 GDKGSAG---LPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLK 2625 Query: 295 SHI----------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 ++G +G GPPG PG G KGE G PG G G PG Sbjct: 2626 GERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPG 2674 Score = 79.3 bits (194), Expect = 6e-15 Identities = 44/102 (43%), Positives = 50/102 (49%), Gaps = 14/102 (13%) Query: 246 PGPPGLPGGQGPPGSP---------GPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296 PG PG G G PG+P G +GSPG PG PG PG GP+G GP G Sbjct: 2244 PGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVV 2303 Query: 297 IKQGRRGPVGPPGA-----PGRDGSKGERGAPGPRGSPGPPG 333 G +G G PG G G+KG+RG PGPRG G G Sbjct: 2304 GLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAG 2345 Score = 79.0 bits (193), Expect = 7e-15 Identities = 41/90 (45%), Positives = 48/90 (53%), Gaps = 5/90 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G G+PG +G G PGP+G G PG+PG G GP G G GP + G G G Sbjct: 2129 GDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPV--GGHGDPG 2186 Query: 307 PPGAPGRDGSKGERGAPGPRGSP---GPPG 333 PPGAPG G G +G G +G P GPPG Sbjct: 2187 PPGAPGLAGPAGPQGPSGLKGEPGETGPPG 2216 Score = 78.6 bits (192), Expect = 1e-14 Identities = 48/113 (42%), Positives = 52/113 (46%), Gaps = 24/113 (21%) Query: 245 LPGPPGLPGGQGP------------------PGSPGPKGSPGFPGMPGPPGQPGPRGSMG 286 LPGP G PG +GP PG PG KG PG G PGP G G G G Sbjct: 1330 LPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRG 1389 Query: 287 PMGPSPDLSHIKQGRRGPVGPPG------APGRDGSKGERGAPGPRGSPGPPG 333 P G +G RG GPPG APG G G G+PGP+G GPPG Sbjct: 1390 PPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPG 1442 Score = 77.8 bits (190), Expect = 2e-14 Identities = 41/88 (46%), Positives = 43/88 (48%), Gaps = 5/88 (5%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG GL G GPPG PG G G PG GPPG +G G G + G G Sbjct: 1259 PGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADG-----RPGSPGRA 1313 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG PG G KG G PGPRG PG G Sbjct: 1314 GNPGTPGAPGLKGSPGLPGPRGDPGERG 1341 Score = 77.8 bits (190), Expect = 2e-14 Identities = 45/95 (47%), Positives = 48/95 (50%), Gaps = 16/95 (16%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSMGPMGPSPDLSHIKQG 300 G PGLPG G G PG G G G PGP G+ PG G GP+GP G Sbjct: 2392 GLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGP--------PG 2443 Query: 301 RRGPVGPPGAPGRDGSKGERGA--PGPRGSPGPPG 333 G VGPPGA G G KG+ G PGPRG G PG Sbjct: 2444 PPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPG 2478 Score = 77.8 bits (190), Expect = 2e-14 Identities = 45/111 (40%), Positives = 54/111 (48%), Gaps = 10/111 (9%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSP---GPKGSPGFPGMPGPPGQPGPRGSMGPMG 289 + G++ + L G G G GPPG P G KG G PG+PG G PG G +GP G Sbjct: 2624 LKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKG 2683 Query: 290 -------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P P ++G RG G G PG G+ G G PGP GS GP G Sbjct: 2684 DRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRG 2734 Score = 77.4 bits (189), Expect = 2e-14 Identities = 44/113 (38%), Positives = 51/113 (45%), Gaps = 14/113 (12%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 GD L G G PG +GP G G +G PG G G PG GP+G G GP Sbjct: 1646 GDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPP 1705 Query: 295 SHI--------------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 + +G+ GP GP G PG G+ GERG G RG PGP G Sbjct: 1706 GRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG 1758 Score = 77.0 bits (188), Expect = 3e-14 Identities = 43/91 (47%), Positives = 48/91 (52%), Gaps = 9/91 (9%) Query: 244 YLP-GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 Y P G G PG G G GP G PG PG G PG GP GS G ++G Sbjct: 1250 YCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKG--------ERGFP 1301 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G PG+PGR G+ G GAPG +GSPG PG Sbjct: 1302 GADGRPGSPGRAGNPGTPGAPGLKGSPGLPG 1332 Score = 76.6 bits (187), Expect = 4e-14 Identities = 45/110 (40%), Positives = 51/110 (46%), Gaps = 21/110 (19%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 L G PG G +G PG G KG G G PG PG+ G +G+ GP G D G GP Sbjct: 2322 LVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGP 2381 Query: 305 VGPPGA------------------PGRDGSKGERGAPGP---RGSPGPPG 333 GPPG PG+ G +GE G PGP RG GPPG Sbjct: 2382 PGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPG 2431 Score = 76.3 bits (186), Expect = 5e-14 Identities = 48/126 (38%), Positives = 55/126 (43%), Gaps = 32/126 (25%) Query: 240 ASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQP--------GPRGSMGPMGPS 291 A + LPG G PG +GP G PGP G G G PG PG P GP+G G +GP+ Sbjct: 1503 AGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPA 1562 Query: 292 -PDLSHIKQGRRGP-----------------------VGPPGAPGRDGSKGERGAPGPRG 327 P + QG RGP G G PG G GE+G PG G Sbjct: 1563 GPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPG 1622 Query: 328 SPGPPG 333 PGP G Sbjct: 1623 PPGPVG 1628 Score = 76.3 bits (186), Expect = 5e-14 Identities = 43/102 (42%), Positives = 48/102 (47%), Gaps = 14/102 (13%) Query: 246 PGPPGLPGG-------------QGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292 PGPPG PG G G GP+G G PG+PG PG+ G G GP GP Sbjct: 1699 PGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG 1758 Query: 293 DLS-HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 D G +G GPPG GR G G+ GA GP G G G Sbjct: 1759 DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAG 1800 Score = 75.5 bits (184), Expect = 8e-14 Identities = 44/97 (45%), Positives = 47/97 (48%), Gaps = 17/97 (17%) Query: 246 PGPPGLPGGQGP---------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296 PG PG PG GP G GP G PG PG G G G G GP+G D Sbjct: 1618 PGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGD--- 1674 Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 QG G G G+PG G KG+RG PGP PGPPG Sbjct: 1675 --QGDPGEDGRNGSPGSSGPKGDRGEPGP---PGPPG 1706 Score = 75.5 bits (184), Expect = 8e-14 Identities = 47/118 (39%), Positives = 53/118 (44%), Gaps = 18/118 (15%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSP-----------GFPGMPGPPGQPGPRG 283 GD+ L G G G G PG G KG+P G PG PGPPG PG +G Sbjct: 2330 GDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKG 2389 Query: 284 SMG----PMGPSPDLSHIKQGRRGPVGPPGAPGR---DGSKGERGAPGPRGSPGPPGS 334 +G P P + G RG +G PG G G G G PGP G PGPPGS Sbjct: 2390 DLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGS 2447 Score = 75.1 bits (183), Expect = 1e-13 Identities = 44/114 (38%), Positives = 49/114 (42%), Gaps = 23/114 (20%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G PG PG G G G +GSPG PG PG PG GP+G GP G G +G G Sbjct: 2254 GKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKG 2313 Query: 307 PPGA-----PGRDGSKGERGAPGPRGS------------------PGPPGSFDF 337 PG G G+KG+RG PGPRG G PG F Sbjct: 2314 APGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGF 2367 Score = 74.7 bits (182), Expect = 1e-13 Identities = 48/123 (39%), Positives = 52/123 (42%), Gaps = 35/123 (28%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPG-------------QPGPRGSMGPMGPSPD 293 G PG G G PGS GPKG G PG PGPPG +PG RG GP GP D Sbjct: 1676 GDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGD 1735 Query: 294 LS-------HIKQGRRGPVGPPGAPGRDGSKGERG---------------APGPRGSPGP 331 +G RGP GP G PG G GE+G PG G GP Sbjct: 1736 PGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGP 1795 Query: 332 PGS 334 G+ Sbjct: 1796 NGA 1798 Score = 73.9 bits (180), Expect = 2e-13 Identities = 48/108 (44%), Positives = 55/108 (50%), Gaps = 20/108 (18%) Query: 246 PGPPG---LPGGQGPPGSPGPKGSP------GFPGMPGPPGQP--------GPRGSMGPM 288 PGP G LPG G PG+ GP+G P G G PG PG P GP+G G + Sbjct: 1500 PGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDV 1559 Query: 289 GPS-PDLSHIKQGRRGPVG--PPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP+ P + QG RGP G PG PG G G+RG G G GPPG Sbjct: 1560 GPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPG 1607 Score = 73.9 bits (180), Expect = 2e-13 Identities = 44/93 (47%), Positives = 49/93 (52%), Gaps = 7/93 (7%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLSHIKQGRRG 303 PGP G G G PG G G G PG+ GP G PGP G G GP +P L+ G +G Sbjct: 2143 PGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAG-PAGPQG 2201 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGS---PGPPG 333 P G G PG G G RG GP G+ PGPPG Sbjct: 2202 PSGLKGEPGETGPPG-RGLTGPTGAVGLPGPPG 2233 Score = 73.6 bits (179), Expect = 3e-13 Identities = 46/110 (41%), Positives = 56/110 (50%), Gaps = 10/110 (9%) Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPP--GQPGPRGSMGPMG-P 290 +G++ LA G PG G GPPGS GP G+ G G G P G PGPRG G G Sbjct: 2421 SGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIR 2480 Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSP-------GPPG 333 D ++G RG GPPG+ G G KG+ G+ G +G GPPG Sbjct: 2481 GEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPG 2530 Score = 73.2 bits (178), Expect = 4e-13 Identities = 45/120 (37%), Positives = 52/120 (43%), Gaps = 29/120 (24%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGP---------------------KGSPGFPGMP 273 GD+ T GPPG G G G PG +G PG PG+P Sbjct: 1592 GDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLP 1651 Query: 274 GPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G G+ G RG+ G GP G +G G PG GR+GS G G G RG PGPPG Sbjct: 1652 GKAGERGLRGAPGVRGP--------VGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPG 1703 Score = 72.8 bits (177), Expect = 5e-13 Identities = 42/90 (46%), Positives = 47/90 (52%), Gaps = 11/90 (12%) Query: 247 GPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303 GP GL G +GP G PG KGS G PG G G PG RG +GP G + G G Sbjct: 2542 GPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQG--------QPGAAG 2593 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PG+PG+DG G RG G G GP G Sbjct: 2594 IPGDPGSPGKDGVPGIRGEKGDVGFMGPRG 2623 Score = 72.0 bits (175), Expect = 9e-13 Identities = 40/88 (45%), Positives = 44/88 (50%), Gaps = 9/88 (10%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G G G +G G G +G+PG G GPPG PGP G G P G G G Sbjct: 1860 GDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFP---------GVPGGTG 1910 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGS 334 P G G GSKGE+G PG RG G PGS Sbjct: 1911 PKGDRGETGSKGEQGLPGERGLRGEPGS 1938 Score = 71.2 bits (173), Expect = 2e-12 Identities = 40/93 (43%), Positives = 48/93 (51%), Gaps = 6/93 (6%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GPPG PG GPPG+ G KG G PG+ G PGPRG G G + + G+ GP G Sbjct: 2440 GPPGPPGSVGPPGASGLKGDKGDPGV----GLPGPRGERGEPGIRGEDG--RPGQEGPRG 2493 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLL 339 G PG G +GE+G G G G G +L Sbjct: 2494 LTGPPGSRGERGEKGDVGSAGLKGDKGDSAVIL 2526 Score = 70.5 bits (171), Expect = 3e-12 Identities = 43/105 (40%), Positives = 51/105 (48%), Gaps = 17/105 (16%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGM---------PGPPGQPGPRGSMGPMGPSPDLSH 296 PGP G G +G G PGP GS G PG+ GPPG G +G G G D + Sbjct: 1485 PGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAV 1544 Query: 297 I------KQGRRGPVGPPGAPGRDGSKGERGAPG--PRGSPGPPG 333 + +G +G VGP G G G +GERG PG G PGP G Sbjct: 1545 VGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKG 1589 Score = 70.1 bits (170), Expect = 3e-12 Identities = 47/130 (36%), Positives = 53/130 (40%), Gaps = 37/130 (28%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGF-------------------------PGMPGPPGQP 279 +PG PGLPG GP G PGP G+PG PG G G P Sbjct: 2276 VPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLP 2335 Query: 280 GPRGSMGPMG----PSPDLSHIKQGRRGP--------VGPPGAPGRDGSKGERGAPGPRG 327 GPRG G G P ++G GP VG PG+PG G G +G G G Sbjct: 2336 GPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPG 2395 Query: 328 SPGPPGSFDF 337 PG PG F Sbjct: 2396 LPGAPGVVGF 2405 Score = 69.3 bits (168), Expect = 6e-12 Identities = 42/95 (44%), Positives = 48/95 (50%), Gaps = 11/95 (11%) Query: 250 GLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL-SHIKQGRRGP---- 304 GLPG +G G PG +G G PG GP G GP GS G G D+ S +G +G Sbjct: 2466 GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVI 2525 Query: 305 VGPPGAPGRDGSKGERGA------PGPRGSPGPPG 333 +GPPG G G GERG GPRG G PG Sbjct: 2526 LGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPG 2560 Score = 68.9 bits (167), Expect = 8e-12 Identities = 43/103 (41%), Positives = 51/103 (49%), Gaps = 14/103 (13%) Query: 245 LPGP------PGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI- 297 LPGP PG+ G G PG GP+G G PG G G+ G GS G G D + I Sbjct: 2467 LPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVIL 2526 Query: 298 ----KQGRRGPVGPPGAPGRDGSKGER---GAPGPRGSPGPPG 333 +G +G +G G G DG KG R G PG +GS G PG Sbjct: 2527 GPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPG 2569 Score = 68.6 bits (166), Expect = 1e-11 Identities = 45/125 (36%), Positives = 50/125 (40%), Gaps = 36/125 (28%) Query: 245 LPGP--------PGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSM----------- 285 LPGP PG+PGG GP G G GS G G+PG G G GS+ Sbjct: 1891 LPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAG 1950 Query: 286 -----------------GPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS 328 G P P+ +G G GPPG G G GERG G RG Sbjct: 1951 IKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGD 2010 Query: 329 PGPPG 333 PGP G Sbjct: 2011 PGPQG 2015 Score = 67.8 bits (164), Expect = 2e-11 Identities = 41/107 (38%), Positives = 51/107 (47%), Gaps = 23/107 (21%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGF------------PGMPGPPGQPGPRGSMGPMGPSP 292 +PG PG PG G PG G KG GF G G G+ G +G GP G P Sbjct: 2594 IPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPG-RP 2652 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPR------GSPGPPG 333 L+ G +G +G PG PG+ G+ G+ G GP+ G PGP G Sbjct: 2653 GLA----GHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKG 2695 Score = 67.4 bits (163), Expect = 2e-11 Identities = 44/106 (41%), Positives = 53/106 (50%), Gaps = 8/106 (7%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP-- 290 + GDK + + GPPG G +G G GP+G G G G G PG +GS G G Sbjct: 2515 LKGDK--GDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKG 2572 Query: 291 SPDLSHIKQGRRGPVGPPGA---PGRDGSKGERGAPGPRGSPGPPG 333 S L ++ G GP G PGA PG GS G+ G PG RG G G Sbjct: 2573 SAGLPGLR-GLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVG 2617 Score = 67.0 bits (162), Expect = 3e-11 Identities = 42/97 (43%), Positives = 47/97 (48%), Gaps = 7/97 (7%) Query: 240 ASNTYLPGPPGLPG--GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI 297 AS T P P P +G G PG G G G PG PG PG G+ GP GP + Sbjct: 1236 ASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSAT-- 1293 Query: 298 KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 +G G PGA GR GS G G PG G+PG GS Sbjct: 1294 ---AKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGS 1327 Score = 65.5 bits (158), Expect = 8e-11 Identities = 44/131 (33%), Positives = 54/131 (41%), Gaps = 27/131 (20%) Query: 222 LPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPG---------- 271 L + D G + G + + G G PG +GP G GP GS G G Sbjct: 2456 LKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGL 2515 Query: 272 ---------MPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGA 322 + GPPG G +G MG GP +G G GP G G G KG +G Sbjct: 2516 KGDKGDSAVILGPPGPRGAKGDMGERGP--------RGLDGDKGPRGDNGDPGDKGSKGE 2567 Query: 323 PGPRGSPGPPG 333 PG +GS G PG Sbjct: 2568 PGDKGSAGLPG 2578 Score = 47.8 bits (112), Expect = 2e-05 Identities = 26/69 (37%), Positives = 32/69 (46%), Gaps = 11/69 (15%) Query: 246 PGPPGLPGGQGPPGSPGPKG-----------SPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 PGPPG G +GP G G KG +PG PG PG G+ G G GP G + Sbjct: 2724 PGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEA 2783 Query: 295 SHIKQGRRG 303 + + RG Sbjct: 2784 ALTEDDIRG 2792 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 95.5 bits (236), Expect = 8e-20 Identities = 47/92 (51%), Positives = 53/92 (57%), Gaps = 3/92 (3%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG---PSPDLSHIKQGR 301 LPGPPG G G PG PGP+G GFPG PG PG PG +G++G G P P G Sbjct: 644 LPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGL 703 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G +GPPG PGR G G G PG +G G PG Sbjct: 704 PGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPG 735 Score = 94.0 bits (232), Expect = 2e-19 Identities = 50/100 (50%), Positives = 56/100 (56%), Gaps = 2/100 (2%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPD 293 G+K + PG PG G G PG PGPKG PG G PG PG PGP+GS+G MG P Sbjct: 963 GEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTP 1022 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G GP G PG PG G+KGE+G GP G G PG Sbjct: 1023 GEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGI-GIPG 1061 Score = 93.6 bits (231), Expect = 3e-19 Identities = 47/87 (54%), Positives = 53/87 (60%), Gaps = 5/87 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G G PG G PG PGPKG PGF GMPG G PG GS G MGP P + G +GP G Sbjct: 1266 GDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGP-PGV----PGFQGPKG 1320 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333 PG G G +G++G PG +G PGPPG Sbjct: 1321 LPGLQGIKGDQGDQGVPGAKGLPGPPG 1347 Score = 92.0 bits (227), Expect = 8e-19 Identities = 47/91 (51%), Positives = 55/91 (60%), Gaps = 7/91 (7%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ--PGPRGSMGPMGPSPDLSHIKQGRR 302 L G PG+PG +G G GP G G PG+PG PG GP+G GP G P L G Sbjct: 1196 LAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQG-QPGL----PGLP 1250 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP+GPPG PG DG KG++G PG G+PG PG Sbjct: 1251 GPMGPPGLPGIDGVKGDKGNPGWPGAPGVPG 1281 Score = 90.1 bits (222), Expect = 3e-18 Identities = 50/105 (47%), Positives = 62/105 (59%), Gaps = 8/105 (7%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294 G++ L + G PG+ G +GP G PG KG G PG+PG G GP G+ G G +P L Sbjct: 49 GERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPG-NPGL 107 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPG 333 I G+ GP GPPG PG +G+KGERG GP G+PGPPG Sbjct: 108 PGI-PGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPG 151 Score = 90.1 bits (222), Expect = 3e-18 Identities = 55/142 (38%), Positives = 61/142 (42%), Gaps = 30/142 (21%) Query: 222 LPNNAADLGKYI--TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQP 279 LP D G+ + +L PG PG PG G PG GP G PGF G PGPPG P Sbjct: 152 LPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPP 211 Query: 280 GPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRD------------------------- 314 GP G G MG S +G +G GPPG PG+ Sbjct: 212 GPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGM 271 Query: 315 ---GSKGERGAPGPRGSPGPPG 333 G KGE G PGPRG PG G Sbjct: 272 PGVGEKGEPGKPGPRGKPGKDG 293 Score = 88.6 bits (218), Expect = 9e-18 Identities = 47/114 (41%), Positives = 57/114 (50%), Gaps = 25/114 (21%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--------PSPDLSHI 297 PG PG PG G PG PG KG GFPG GP G PG +G G +G D+ + Sbjct: 887 PGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSM 946 Query: 298 K-----QGRRGPVGP------------PGAPGRDGSKGERGAPGPRGSPGPPGS 334 K QG +G +GP PG PG+DG G+ G PGP+G PG G+ Sbjct: 947 KGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGT 1000 Score = 88.2 bits (217), Expect = 1e-17 Identities = 47/93 (50%), Positives = 50/93 (53%), Gaps = 14/93 (15%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G PG PG +G PG G KG G PG PG PG PG G GP G ++G GP G Sbjct: 278 GEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQG--------EKGEAGPPG 329 Query: 307 PPG---APGRDGSKGER---GAPGPRGSPGPPG 333 PPG G G KGER G PGPRG PGP G Sbjct: 330 PPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKG 362 Score = 87.8 bits (216), Expect = 2e-17 Identities = 50/110 (45%), Positives = 57/110 (51%), Gaps = 27/110 (24%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGP---------RGSMGPMGPSPDLSH 296 PG PG G +GPPG+ G G+PG PG+PG G PGP +G GP+GP P L Sbjct: 84 PGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGP-PGL-- 140 Query: 297 IKQGRRGPVGPPGAPGRDGS-------------KGERGAPGPRGSPGPPG 333 G G GPPG PG G KGERG PG G+PGPPG Sbjct: 141 --PGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPG 188 Score = 87.4 bits (215), Expect = 2e-17 Identities = 43/84 (51%), Positives = 50/84 (59%), Gaps = 5/84 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 G PGLPG +G G PG G PG PG+PG PGQ GP G G G + +G RGP+G Sbjct: 82 GEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPG-----CNGTKGERGPLG 136 Query: 307 PPGAPGRDGSKGERGAPGPRGSPG 330 PPG PG G+ G G PG +G PG Sbjct: 137 PPGLPGFAGNPGPPGLPGMKGDPG 160 Score = 85.9 bits (211), Expect = 6e-17 Identities = 54/121 (44%), Positives = 61/121 (50%), Gaps = 36/121 (29%) Query: 247 GPPGLPGGQGPPGSPG---------PKGSPGFPGMPGPPGQPGP-------RGSMGPMGP 290 GPPG+PG QGP G PG +G PG G+PGPPG PGP G GP GP Sbjct: 1308 GPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGP 1367 Query: 291 SPDLSHIKQGRRGP------------VGPPGAPGRDGSKGER------GAPGPRGSPGPP 332 P L + QG GP GPPG PG DG+ G++ G GPRG PGPP Sbjct: 1368 -PGLKGL-QGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPP 1425 Query: 333 G 333 G Sbjct: 1426 G 1426 Score = 85.5 bits (210), Expect = 8e-17 Identities = 48/105 (45%), Positives = 50/105 (47%), Gaps = 26/105 (24%) Query: 246 PGPPGL---------------PGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP 290 PGPPG+ PG GP G PGPKG PG PG PGPPG P P + P P Sbjct: 328 PGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFP 387 Query: 291 SPDLSHIKQGRRGPVGPPGAPGRD--GSKGERGAPGPRGSPGPPG 333 G RG G G PG G G G PGP GSPGPPG Sbjct: 388 ---------GERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPG 423 Score = 85.5 bits (210), Expect = 8e-17 Identities = 48/102 (47%), Positives = 56/102 (54%), Gaps = 14/102 (13%) Query: 246 PGPPGLP------GGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-------P 292 PG PGLP GG G PG+PG KG PG PG G PG PG +G+ G G + P Sbjct: 1001 PGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIP 1060 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 L ++G +G G PG+PG G KG G PG GSPG GS Sbjct: 1061 GLRG-EKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGS 1101 Score = 85.1 bits (209), Expect = 1e-16 Identities = 48/101 (47%), Positives = 54/101 (53%), Gaps = 15/101 (14%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGM---PGPPGQPGPRGSMGP-MGPSPDLSHIKQGR 301 PGPPG+PG G G GP G PG PG PGPPG PG +G G +G P + + +G Sbjct: 117 PGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGM--LLKGE 174 Query: 302 RG------PVGPPGAPGRDGSKGE---RGAPGPRGSPGPPG 333 RG GPPG PG G G G PGP G PGPPG Sbjct: 175 RGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPG 215 Score = 84.3 bits (207), Expect = 2e-16 Identities = 50/111 (45%), Positives = 55/111 (49%), Gaps = 21/111 (18%) Query: 242 NTYLPGPPGLPGGQGPPGSP------------GPKGSPGFPGMPGPPGQPGPRGSMGP-M 288 N LPG PG G GPPG P GP G PGF G PGPPG PG +G G + Sbjct: 104 NPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEIL 163 Query: 289 GPSPDLSHIKQGRR------GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G P + + +G R G GPPG PG G G G GP G PGPPG Sbjct: 164 GHVPGM--LLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPG 212 Score = 84.3 bits (207), Expect = 2e-16 Identities = 49/107 (45%), Positives = 53/107 (49%), Gaps = 16/107 (14%) Query: 243 TYLPGPPGLPGGQGPPGSPGPKGSPGF-----------PGMPGPPGQPGPRGSMGPMGPS 291 T LPGP G G GPPGSPGP G PG+ PG GPPG PG G +G +G Sbjct: 401 TSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEK 460 Query: 292 PD-----LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 L G RGP GP G PG G G+ GA G RG PG G Sbjct: 461 GQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDG 507 Score = 84.3 bits (207), Expect = 2e-16 Identities = 45/92 (48%), Positives = 49/92 (53%), Gaps = 8/92 (8%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGM---PGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301 +PGP G G QG PG G G PG PG PG PG PG +G MG MG + G Sbjct: 838 MPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPG-----QPGS 892 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GPVG PG PG G G G+ GPRG PG G Sbjct: 893 PGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKG 924 Score = 82.4 bits (202), Expect = 7e-16 Identities = 49/100 (49%), Positives = 53/100 (53%), Gaps = 13/100 (13%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPG-----------PPGQPGPRGSMGPMGPSPDL 294 PG PG G QG G PGP+G PG PG PG P GQPG G GPMGP P L Sbjct: 1200 PGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGP-PGL 1258 Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 I G +G G PG PG G G +G PG +G PG GS Sbjct: 1259 PGI-DGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGS 1297 Score = 82.0 bits (201), Expect = 9e-16 Identities = 46/91 (50%), Positives = 51/91 (56%), Gaps = 5/91 (5%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPP---GQPGPRGSMGPMGPSPDLSHIKQGRR 302 PG PG G G G G KGSPGFPG PG P G+ GP+G G GP P I G Sbjct: 280 PGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGP-PGPPGIVIG-T 337 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP+G G G G+ G RG PGP+G PG PG Sbjct: 338 GPLGEKGERGYPGTPGPRGEPGPKGFPGLPG 368 Score = 81.6 bits (200), Expect = 1e-15 Identities = 43/88 (48%), Positives = 47/88 (53%), Gaps = 5/88 (5%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306 GPPG P G GP G G KG GFPG PG PG PGP+G G + P P G G G Sbjct: 601 GPPG-PPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPG----PPGAEGLPG 655 Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGS 334 PG PG G +G G PG G PG G+ Sbjct: 656 SPGFPGPQGDRGFPGTPGRPGLPGEKGA 683 Score = 81.3 bits (199), Expect = 1e-15 Identities = 50/118 (42%), Positives = 57/118 (48%), Gaps = 24/118 (20%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGS------PGP-----------KGSPGFPGMPGP 275 + G K + L G G PGG G PGS PGP KG GFPG PG Sbjct: 569 LPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGS 628 Query: 276 PGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 PG PGP+G G + P P G G G PG+PG G +G+RG PG G PG PG Sbjct: 629 PGLPGPKGEPGKIVPLP-------GPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPG 679 Score = 81.3 bits (199), Expect = 1e-15 Identities = 47/102 (46%), Positives = 52/102 (50%), Gaps = 9/102 (8%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-------PDLSHI 297 LPGP G GG G PG+PG KG PG PG G PG PG +G+ G G + P L Sbjct: 1006 LPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGE 1065 Query: 298 K--QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 K QG G G PG G GS G G PG G G PGS + Sbjct: 1066 KGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGY 1107 Score = 80.9 bits (198), Expect = 2e-15 Identities = 48/98 (48%), Positives = 50/98 (51%), Gaps = 9/98 (9%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGP 304 PG PGLPG +G G PG G PG G G PG PGP G G G P D G +G Sbjct: 1108 PGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGE 1167 Query: 305 VGPPG--------APGRDGSKGERGAPGPRGSPGPPGS 334 G PG A G GSKGE G PG GSPG PGS Sbjct: 1168 PGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGS 1205 Score = 80.5 bits (197), Expect = 3e-15 Identities = 51/116 (43%), Positives = 57/116 (49%), Gaps = 13/116 (11%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGM------PGPPGQPGPRGSMGPM 288 GD + G G PG G PG PGPKGSPG G+ PG G PG RG GP Sbjct: 544 GDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPP 603 Query: 289 GP---SPDLSHIKQGRRGPVGPPGAPGRDGSKGERG----APGPRGSPGPPGSFDF 337 GP P +G+ G G PG+PG G KGE G PGP G+ G PGS F Sbjct: 604 GPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGF 659 Score = 80.5 bits (197), Expect = 3e-15 Identities = 47/109 (43%), Positives = 56/109 (51%), Gaps = 11/109 (10%) Query: 235 GDKVLASNTYLPGPPGLPGG----QGPPGSPGPKGSPGFPGM---PGPPGQPGPRGSMGP 287 GD+ + LPGPPG PG +G PG PGP+G PG G+ PGP GQ G G +G Sbjct: 1332 GDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGI 1391 Query: 288 MGPSP----DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPP 332 GP D + ++G GP GP G G G G G PG G PG P Sbjct: 1392 PGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTP 1440 Score = 79.7 bits (195), Expect = 4e-15 Identities = 46/104 (44%), Positives = 52/104 (50%), Gaps = 15/104 (14%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-------PDLSHIK 298 PGPPG G G PG GP G+PG PG G PG PG +G G G P L I Sbjct: 692 PGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIP 751 Query: 299 --QGRRGPVGPPGAPGRDGS------KGERGAPGPRGSPGPPGS 334 G +G +G PG PG G+ +G RG PGP G PG GS Sbjct: 752 GTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGS 795 Score = 79.3 bits (194), Expect = 6e-15 Identities = 47/99 (47%), Positives = 53/99 (53%), Gaps = 16/99 (16%) Query: 246 PGP---PGLPGGQGPPGSPGPKGS------PGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296 PGP PG+ G G PG PGPKGS PG PG G PG PGP+GS G G Sbjct: 989 PGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKG---- 1044 Query: 297 IKQGRRGPVGPP--GAPGRDGSKGERGAPGPRGSPGPPG 333 +G +G GPP G PG G KG++G G GSPG G Sbjct: 1045 -AKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKG 1082 Score = 79.3 bits (194), Expect = 6e-15 Identities = 42/89 (47%), Positives = 49/89 (55%), Gaps = 9/89 (10%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG G PG G PG G KG PG G+PG G+ G G+ GP GP+ G++G Sbjct: 1102 PGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPA--------GQKGEP 1153 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G G PG G KGE G PG RG PG PG+ Sbjct: 1154 GSDGIPGSAGEKGEPGLPG-RGFPGFPGA 1181 Score = 78.6 bits (192), Expect = 1e-14 Identities = 41/93 (44%), Positives = 48/93 (51%), Gaps = 5/93 (5%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP-----SPDLSHIKQG 300 PGP G PG G PG PG KG G PG G G PGP+G+ G +G P + Sbjct: 479 PGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLR 538 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +G G PG PG+ G G G+PG G PG PG Sbjct: 539 LKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPG 571 Score = 78.6 bits (192), Expect = 1e-14 Identities = 49/109 (44%), Positives = 58/109 (53%), Gaps = 9/109 (8%) Query: 235 GDKVLASNTYLPG---PPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS 291 GDK L +PG GLPG GP G G KG PG G+PG G+ G G G P Sbjct: 1118 GDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPG 1177 Query: 292 PDLSHIKQGRRGPVGPPG---APGRDGSKGER---GAPGPRGSPGPPGS 334 + +G +G VG PG +PG GSKGE+ G PGP+G PG PGS Sbjct: 1178 FPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGS 1226 Score = 78.2 bits (191), Expect = 1e-14 Identities = 47/106 (44%), Positives = 50/106 (47%), Gaps = 19/106 (17%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 LPGP G PG G G GP G GFPG G G PGP G GP GP D +G+ G Sbjct: 569 LPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPG-YGPAGPIGD-----KGQAGF 622 Query: 305 VGPPGAPGRDGSKGE-------------RGAPGPRGSPGPPGSFDF 337 G PG+PG G KGE G PG G PGP G F Sbjct: 623 PGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGF 668 Score = 77.4 bits (189), Expect = 2e-14 Identities = 49/117 (41%), Positives = 54/117 (46%), Gaps = 29/117 (24%) Query: 246 PGPPGLPG--------GQGPPGSPGPKGSPGFPG---MPGPPGQPGPRGSMGPMG----- 289 PG PGLPG G G PG PGPKG G PG PG PG+PG G G G Sbjct: 672 PGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQK 731 Query: 290 --PSPDLSHIK-----------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P L +K G +G +G PG PG G+ G G G RG PGPPG Sbjct: 732 GEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPG 788 Score = 77.0 bits (188), Expect = 3e-14 Identities = 51/107 (47%), Positives = 57/107 (53%), Gaps = 19/107 (17%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP------------PGQPGPRGSMGPMGPSP 292 LPG GLPG G PG+PG KGS G PG+PG G+PGP G G +G SP Sbjct: 738 LPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVG-SP 796 Query: 293 DLSHI-KQGRRGP---VGPPGAPGRDGSKGERGAPGPRG--SPGPPG 333 + I G RGP GPPG G G KGE+G PG G PGP G Sbjct: 797 GVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKG 843 Score = 77.0 bits (188), Expect = 3e-14 Identities = 46/95 (48%), Positives = 50/95 (52%), Gaps = 7/95 (7%) Query: 246 PGPPGLPGGQGPPGSPG--PKGSPGFPGMPGPPGQPGPRGSMGPMG----PSPDLSHIKQ 299 PGPPGLPG G PG PG P G+ G PG GPPG GP G G G P D+ K Sbjct: 784 PGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPK- 842 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G +G G PG G+ G G G G G PG PGS Sbjct: 843 GDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGS 877 Score = 76.3 bits (186), Expect = 5e-14 Identities = 50/123 (40%), Positives = 55/123 (44%), Gaps = 34/123 (27%) Query: 245 LPGPPGLPGGQGPPGSPGP-------------KGSPGFPGMPGP------------PGQP 279 +PGP G PG G PG+ G KG PGFPG PG PG P Sbjct: 511 VPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLP 570 Query: 280 GPRGSMGPMG----PSPDLSHIKQGRRGPVGPPGAPGRD-----GSKGERGAPGPRGSPG 330 GP+GS G +G P G RG GPPG PG G KG+ G PG GSPG Sbjct: 571 GPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPG 630 Query: 331 PPG 333 PG Sbjct: 631 LPG 633 Score = 75.9 bits (185), Expect = 6e-14 Identities = 43/96 (44%), Positives = 52/96 (54%), Gaps = 11/96 (11%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSMGPMGPSPDLSHIKQG 300 G PG+ G G PG PG +G+PG PG PG G+ PG GS GP+G +P L G Sbjct: 849 GLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVG-APGL----PG 903 Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFD 336 +G G PG+ G G G +G G G PG PGS D Sbjct: 904 EKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMD 939 Score = 75.9 bits (185), Expect = 6e-14 Identities = 49/114 (42%), Positives = 56/114 (49%), Gaps = 17/114 (14%) Query: 233 ITGDKVLASNTYLPGPPGL--PGGQGP---------PGSPGPKGSPGFPGMPGPPGQPGP 281 + GDK GPPG+ PG +G PGSPG KG G G+PG PG PG Sbjct: 1039 LPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGL 1098 Query: 282 RGSMGPMG--PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 +GS G +G SP L G +G G PG G G KGE G PG G GP G Sbjct: 1099 KGSPGSVGYPGSPGL----PGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAG 1148 Score = 74.7 bits (182), Expect = 1e-13 Identities = 48/130 (36%), Positives = 55/130 (42%), Gaps = 30/130 (23%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQ--------GPPGSPGPKGSPGFPGMPG 274 P +G G K + + GPPG+PG G G KG PGF GMPG Sbjct: 214 PGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPG 273 Query: 275 -----PPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS- 328 PG+PGPRG G K G +G G PG PG G G G GP+G Sbjct: 274 VGEKGEPGKPGPRGKPG-----------KDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEK 322 Query: 329 -----PGPPG 333 PGPPG Sbjct: 323 GEAGPPGPPG 332 Score = 74.7 bits (182), Expect = 1e-13 Identities = 50/115 (43%), Positives = 56/115 (48%), Gaps = 27/115 (23%) Query: 245 LPGPPGLPGGQGPPGS--PGPKGSPGFPGMPGPPGQ------PGPRGSMGPMGPSPDLSH 296 LPG PG+ G +G PG PG KG PG PG+PG PG+ PG G G +GP P L Sbjct: 721 LPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGP-PGL-- 777 Query: 297 IKQGRRGPVGPPGAPGRDGSKGE--------------RGAPGPRGSPGPPGSFDF 337 QG RG GPPG PG GS G +G PG G PG G F Sbjct: 778 --QGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGF 830 Score = 73.9 bits (180), Expect = 2e-13 Identities = 51/123 (41%), Positives = 57/123 (46%), Gaps = 25/123 (20%) Query: 233 ITGDKVLASNTYLPGPPGL------------PGGQGPPGSPGP---KGSPGFPGMPGPPG 277 + GDK + LPG PG G QG G GP KGS G PG PG PG Sbjct: 922 LKGDK---GDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPG 978 Query: 278 QPGPRGSMGPMGP--SPDLSHIK-----QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPG 330 + G G G GP P +S G +G VG G PG G KG G PGP+GSPG Sbjct: 979 KDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPG 1038 Query: 331 PPG 333 PG Sbjct: 1039 LPG 1041 Score = 71.2 bits (173), Expect = 2e-12 Identities = 47/115 (40%), Positives = 51/115 (44%), Gaps = 24/115 (20%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSP----------GFPGMPGPPGQPGPRGS 284 GD+ L + G PG G G G PG KG P G G PG PGQPG G Sbjct: 498 GDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGR 557 Query: 285 MGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGA------PGPRGSPGPPG 333 G G + G G GP G+PG G KGERG PG RG GPPG Sbjct: 558 AGSPG--------RDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPG 604 Score = 67.0 bits (162), Expect = 3e-11 Identities = 36/74 (48%), Positives = 38/74 (51%), Gaps = 10/74 (13%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----PSPDLSHIKQG 300 LPGP G G G G PGP G PGF G PG G+ GP G GP G P PD G Sbjct: 1376 LPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPD------G 1429 Query: 301 RRGPVGPPGAPGRD 314 G +GPPG P D Sbjct: 1430 LPGSMGPPGTPSVD 1443 Score = 58.9 bits (141), Expect = 8e-09 Identities = 29/55 (52%), Positives = 33/55 (60%), Gaps = 4/55 (7%) Query: 245 LPGPPGLPGGQGPPGSP---GPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296 +PGPPG+PG G PG GP G G G PGPPG G GSMGP G +P + H Sbjct: 1391 IPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPG-TPSVDH 1444 Score = 54.3 bits (129), Expect = 2e-07 Identities = 29/76 (38%), Positives = 35/76 (46%), Gaps = 20/76 (26%) Query: 259 GSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKG 318 G G KG G PG+ G G PG +GP GP G PG+ G G Sbjct: 43 GVKGQKGERGLPGLQGVIGFPG--------------------MQGPEGPQGPPGQKGDTG 82 Query: 319 ERGAPGPRGSPGPPGS 334 E G PG +G+ GPPG+ Sbjct: 83 EPGLPGTKGTRGPPGA 98 Score = 33.9 bits (76), Expect = 0.27 Identities = 16/38 (42%), Positives = 21/38 (55%) Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 H +G++G G PG G G G +G GP+G PG G Sbjct: 42 HGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKG 79 >gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] Length = 703 Score = 95.5 bits (236), Expect = 8e-20 Identities = 56/141 (39%), Positives = 62/141 (43%), Gaps = 39/141 (27%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF------------------------P 270 G LA +PG GLPG GPPG GPKG PGF P Sbjct: 397 GPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQP 456 Query: 271 GMPGPPGQPGPRGSMGPMGPS--PDLSHI-------------KQGRRGPVGPPGAPGRDG 315 G+ GP G PG +G GP+GP P L + G GP GPPG PG G Sbjct: 457 GLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPG 516 Query: 316 SKGERGAPGPRGSPGPPGSFD 336 G G PGP G PG PG+FD Sbjct: 517 ITGPPGPPGPPGPPGAPGAFD 537 Score = 92.0 bits (227), Expect = 8e-19 Identities = 49/92 (53%), Positives = 53/92 (57%), Gaps = 7/92 (7%) Query: 248 PPGLPGGQGPPGSPGPKGSPGFPGMPGPP--GQPGPRGSMGPMGPSPDLSHIKQ----GR 301 P L G GPPG PGP+G PG PG PG P G+PG G GP GP P S + + G Sbjct: 72 PMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGP-PGFSRMGKAGPPGL 130 Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G VGPPG PG G G RG G RG PGPPG Sbjct: 131 PGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPG 162 Score = 90.1 bits (222), Expect = 3e-18 Identities = 48/104 (46%), Positives = 56/104 (53%), Gaps = 15/104 (14%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP-----PGQPGPRGSMGPMG---------- 289 +PG GLPG QGP G+ G G+ G PG+ GP PG PGP+G GP G Sbjct: 282 VPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGE 341 Query: 290 PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P D +QG +G GPPG PG G G RG PGP+G GP G Sbjct: 342 PGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGG 385 Score = 89.7 bits (221), Expect = 4e-18 Identities = 46/88 (52%), Positives = 50/88 (56%), Gaps = 5/88 (5%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG G PG QGP G GP G PG G+PG G PGP+G GP GP P + G RG Sbjct: 342 PGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGP-PGV----PGIRGDQ 396 Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP G G+ G GERG PG G PGP G Sbjct: 397 GPSGLAGKPGVPGERGLPGAHGPPGPTG 424 Score = 89.4 bits (220), Expect = 5e-18 Identities = 51/112 (45%), Positives = 57/112 (50%), Gaps = 33/112 (29%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGF------------PGMPGP-----PGQPGPRGSMGPMG 289 GPPGLPG GPPG PG +G PG PG+PGP PG+PG +G GP G Sbjct: 126 GPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPG 185 Query: 290 PSPDLSHIKQGRRGPVGPPGAPGRDGSKGER--------GAPGPRGSPGPPG 333 QG GP G PG PG G KG+ GAPG G+PGPPG Sbjct: 186 --------FQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPG 229 Score = 83.6 bits (205), Expect = 3e-16 Identities = 47/103 (45%), Positives = 51/103 (49%), Gaps = 17/103 (16%) Query: 245 LPGPPGLPGGQGPPGSPGPKGS-----------PGFPGMPGPPGQPGPRGSMGPMG---P 290 +PGPPG G GP G PGP G PG PG PG G PGP G GP G P Sbjct: 180 VPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKP 239 Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 D G +G GPPG P G +GE GA GP+G PG G Sbjct: 240 GLDGLPGAPGDKGESGPPGVP---GPRGEPGAVGPKGPPGVDG 279 Score = 82.8 bits (203), Expect = 5e-16 Identities = 49/102 (48%), Positives = 55/102 (53%), Gaps = 15/102 (14%) Query: 246 PGPPGLPGGQGP--PGSPGPK---GSPGFPGMPGPPGQPGPRGSMGPMGPS----PDLSH 296 PGPPGLPG G PG PG + G PGF G PGP G+PGP G G G + P L Sbjct: 158 PGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPG 217 Query: 297 IKQGRRGPVGPPGAP-----GRDGSKGERGAPGPRGSPGPPG 333 G+ G GPPG P G+ G G GAPG +G GPPG Sbjct: 218 -APGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPG 258 Score = 82.8 bits (203), Expect = 5e-16 Identities = 48/102 (47%), Positives = 52/102 (50%), Gaps = 15/102 (14%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ-----PGPRGSMGPMGPSPDLSHIKQ 299 LPG PG G GPPG PGP+G PG G GPPG PG G GP GPS + Sbjct: 244 LPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKG--EP 301 Query: 300 GRRGP---VGP-----PGAPGRDGSKGERGAPGPRGSPGPPG 333 G RGP +GP PG PG G +G G PG G G PG Sbjct: 302 GTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPG 343 Score = 82.8 bits (203), Expect = 5e-16 Identities = 51/112 (45%), Positives = 59/112 (52%), Gaps = 25/112 (22%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPG--------MPGPPG------QPGPRGSMGPMGPS- 291 GPPG+PG +G PG+ GPKG PG G +PGP G +PG RG G +GP+ Sbjct: 255 GPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG 314 Query: 292 ---PDLSHIKQGRRGPVGPPGA------PGRDGSKGERGAPGPRGSPGPPGS 334 P L K G RGP G PG PG DG GE+G G G PG PGS Sbjct: 315 YGMPGLPGPK-GDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGS 365 Score = 82.0 bits (201), Expect = 9e-16 Identities = 45/89 (50%), Positives = 47/89 (52%), Gaps = 5/89 (5%) Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304 L GPPGLPG G PG GP G G G GPPG PG RG GP G + K G G Sbjct: 356 LGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAG-----KPGVPGE 410 Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G PGA G G G +G PG G PG PG Sbjct: 411 RGLPGAHGPPGPTGPKGEPGFTGRPGGPG 439 Score = 79.7 bits (195), Expect = 4e-15 Identities = 47/107 (43%), Positives = 55/107 (51%), Gaps = 17/107 (15%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKG-----SPGFPGMPGPP---GQPGPRGSMG 286 G L + G GL G GPPG PGP G PG G+PGPP G+PGP+G G Sbjct: 138 GQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPG 197 Query: 287 PMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P G +G +G G G PG G+ G+ GAPGP G PGP G Sbjct: 198 PPG--------DRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPAG 235 Score = 78.2 bits (191), Expect = 1e-14 Identities = 44/101 (43%), Positives = 47/101 (46%), Gaps = 5/101 (4%) Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292 + GD+ PG G G GPPG PG G PG G PGP G+ GP G G G Sbjct: 335 LLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRG 394 Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 D QG G G PG PG G G G PGP G G PG Sbjct: 395 D-----QGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPG 430 Score = 78.2 bits (191), Expect = 1e-14 Identities = 52/123 (42%), Positives = 62/123 (50%), Gaps = 9/123 (7%) Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF---PGMPGPPGQ- 278 P A LG+ GD L L GP G+PG QGP G GP+G PG PG+PGPPG+ Sbjct: 438 PGVAGALGQ--KGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEG 495 Query: 279 -PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337 G G+ GP GP P + G GP GPPG PG G+ G G G P G + Sbjct: 496 RAGEPGTAGPTGP-PGVPG-SPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEG 553 Query: 338 LLL 340 +L Sbjct: 554 AVL 556 Score = 77.0 bits (188), Expect = 3e-14 Identities = 50/113 (44%), Positives = 57/113 (50%), Gaps = 25/113 (22%) Query: 246 PGPPGLPG-------GQ-GPPGSPGPKGSPGFPGMPGP-----------PGQPGPRGSMG 286 PGPPG G GQ G PG+PG G+PG PG+PGP PG PG +G G Sbjct: 196 PGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESG 255 Query: 287 PMG-PSPDLSHIKQGRRGP-----VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P G P P G +GP VG PGA G G +G GA G G+ GPPG Sbjct: 256 PPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPG 308 Score = 44.7 bits (104), Expect = 2e-04 Identities = 24/57 (42%), Positives = 27/57 (47%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303 GP G PG G PG GP G PG PG PG PG G G P+ + G+ G Sbjct: 504 GPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGG 560 Score = 40.0 bits (92), Expect = 0.004 Identities = 35/96 (36%), Positives = 39/96 (40%), Gaps = 17/96 (17%) Query: 254 GQGPPGSPG--PKGSPGF-------PGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRG 303 G GP S G G+ G+ P GP G P G + P P L +G G Sbjct: 21 GCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPG 80 Query: 304 PV------GPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P GPPG PG G G G PG G PGP G Sbjct: 81 PPGKPGPRGPPGPPGFPGKPG-MGKPGLHGQPGPAG 115 Score = 40.0 bits (92), Expect = 0.004 Identities = 22/59 (37%), Positives = 29/59 (49%), Gaps = 2/59 (3%) Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292 TG + + + GPPG PG GPPG+PG G G+ P G G G++ G P Sbjct: 506 TGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG--GVEGAVLGKGGKP 562 >gi|119829187 alpha 1 type XVII collagen [Homo sapiens] Length = 1497 Score = 95.5 bits (236), Expect = 8e-20 Identities = 60/150 (40%), Positives = 75/150 (50%), Gaps = 13/150 (8%) Query: 194 KAGTCCATCKEFYQMKQTVLQLKQKIALL---PNNAADLGKY-ITGDKVLASNTYLPGPP 249 K G + +E + + L ++Q+ L P D+G GD+ +PGP Sbjct: 537 KIGLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPL 596 Query: 250 GLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR------G 303 G PG QGP G KGS G PGM GP GQ G G MGP G + ++G R G Sbjct: 597 GHPGPQGPKGQ---KGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPG 653 Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 P GPPG PG G KG G+PGP+G PGP G Sbjct: 654 PHGPPGVPGSVGPKGSSGSPGPQGPPGPVG 683 Score = 92.8 bits (229), Expect = 5e-19 Identities = 56/136 (41%), Positives = 64/136 (47%), Gaps = 40/136 (29%) Query: 230 GKYITGDKVLASNTYLPGPPGLPGGQGPPG---SPGPKGSPGFPG------MPGPPGQPG 280 GK +T + +S +PGPPG PG GPPG +PGP G G PG + GPPG PG Sbjct: 806 GKIVTSEG--SSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPG 863 Query: 281 PRGSMGPMGPSPDLSHIKQGRRGPVG-----------------------PPGAPGRDGSK 317 PRG GP P P G RGP G PPG PG G K Sbjct: 864 PRGPPGPSIPGPP------GPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPK 917 Query: 318 GERGAPGPRGSPGPPG 333 G++G PGPRG G G Sbjct: 918 GDQGPPGPRGHQGEQG 933 Score = 92.4 bits (228), Expect = 6e-19 Identities = 55/127 (43%), Positives = 69/127 (54%), Gaps = 10/127 (7%) Query: 218 KIALLPNNAADLGKYITGDKVLAS-NTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPP 276 KI L ++ +L ++ ++ N L G PG G G PG G +G PG PG+PGP Sbjct: 537 KIGLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPL 596 Query: 277 GQPGPRGSMGPMG----PSPDLSHIKQGRRGPVGPPGAPGRDGS--KGERGA---PGPRG 327 G PGP+G G G P + ++GR GP+GP G G GS KGERGA PGP G Sbjct: 597 GHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHG 656 Query: 328 SPGPPGS 334 PG PGS Sbjct: 657 PPGVPGS 663 Score = 82.8 bits (203), Expect = 5e-16 Identities = 53/139 (38%), Positives = 58/139 (41%), Gaps = 50/139 (35%) Query: 246 PGP--PGLPGGQGPPGS--PGPKGSPG---------FPGMPGPPGQPGPRGSMGPMGP-- 290 PGP PG PG +GPPG PGP G PG G PGPPG PGP+G GP GP Sbjct: 868 PGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRG 927 Query: 291 -----------SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPG--------------- 324 + S +GP GPPG G G KG+ G PG Sbjct: 928 HQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSS 987 Query: 325 ---------PRGSPGPPGS 334 P G PGPPGS Sbjct: 988 TMYVSGPPGPPGPPGPPGS 1006 Score = 82.0 bits (201), Expect = 9e-16 Identities = 42/94 (44%), Positives = 50/94 (53%), Gaps = 7/94 (7%) Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ------- 299 GPPG G QG G G G PG G+PG G+PG +G+MGP GP + Sbjct: 704 GPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMP 763 Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 G RGP GP G PG+ G G +G G G+PG PG Sbjct: 764 GIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPG 797 Score = 81.6 bits (200), Expect = 1e-15 Identities = 46/105 (43%), Positives = 55/105 (52%), Gaps = 8/105 (7%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGS---PGPKGSPG---FPGMPGPPGQPGPRGSMGPM 288 G++ A GPPG+PG GP GS PGP+G PG G+ G G PG +G GPM Sbjct: 644 GERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPM 703 Query: 289 GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333 GP QG +GP G G PG G G G PG +G+ GP G Sbjct: 704 GPPGPKG--DQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAG 746 Score = 80.1 bits (196), Expect = 3e-15 Identities = 45/101 (44%), Positives = 49/101 (48%), Gaps = 20/101 (19%) Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305 PG G G GP G GP+G G GMPG G PGP G G G + G +GP Sbjct: 736 PGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLT--------GPQGPQ 787 Query: 306 GPPGAPGRDGSKGERGAPGP------------RGSPGPPGS 334 G PG PGR G KGE GAPG G PGPPG+ Sbjct: 788 GLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGA 828 Score = 79.0 bits (193), Expect = 7e-15 Identities = 46/123 (37%), Positives = 52/123 (42%), Gaps = 32/123 (26%) Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPG-------------------- 274 G++ L + GPPG G G PG GP+G G PG PG Sbjct: 755 GEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGS 814 Query: 275 ----PPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPG 330 PG PGP G+MGP GP G GP GP G PG +G PGP G G Sbjct: 815 SMLTVPGPPGPPGAMGPPGP--------PGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRG 866 Query: 331 PPG 333 PPG Sbjct: 867 PPG 869 Score = 77.4 bits (189), Expect = 2e-14 Identities = 53/163 (32%), Positives = 62/163 (38%), Gaps = 55/163 (33%) Query: 222 LPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPG------- 274 LP G +++ + S PGPPG PG +G G PGP+G G G+PG Sbjct: 886 LPGPPGPPGSFLSNSETFLSGP--PGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSS 943 Query: 275 --------PPGQPGPRGSMG-------------PMGPSPDLSHIKQGRRGPVGPPGAPGR 313 PPG PGP+G G P GPS S GP GPPG PG Sbjct: 944 SFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGP 1003 Query: 314 DGS-------------------------KGERGAPGPRGSPGP 331 GS G +G PGP G PGP Sbjct: 1004 PGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGP 1046 Score = 75.1 bits (183), Expect = 1e-13 Identities = 42/98 (42%), Positives = 49/98 (50%), Gaps = 2/98 (2%) Query: 243 TYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302 T +PG G PG G PG PG G G G+PG PG+PG +G P P ++ Sbjct: 760 TGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGE--PGAPGKIVTSEGSSML 817 Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLL 340 GPPG PG G G GAPGP G G PG + L L Sbjct: 818 TVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNL 855 Score = 65.5 bits (158), Expect = 8e-11 Identities = 35/94 (37%), Positives = 43/94 (45%), Gaps = 32/94 (34%) Query: 255 QGPPGSPGPKGSPG---------------------FPGMPGPPGQPGPRGSMGPMGPSPD 293 QGPPG PGP+G PG + + GPPGQ G G+ GP Sbjct: 1398 QGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGP------ 1451 Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRG 327 +G RGP GPPG PG G +G +G G +G Sbjct: 1452 -----KGDRGPAGPPGHPGPPGPRGHKGEKGDKG 1480 Score = 60.8 bits (146), Expect = 2e-09 Identities = 45/134 (33%), Positives = 47/134 (35%), Gaps = 66/134 (49%) Query: 246 PGPPGLPGGQ-----------------GPPGSPGPKGSPG-------------------- 268 PGPPGLPG GPPG PGP G PG Sbjct: 1151 PGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGL 1210 Query: 269 --FPGMPGPPGQPGPRGSMGPMGP---------------------SPDLSHIKQGRRGPV 305 PG PGPPG PGPRG G G SPD+ R V Sbjct: 1211 SFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDV------RSFIV 1264 Query: 306 GPPGAPGRDGSKGE 319 GPPG PG G G+ Sbjct: 1265 GPPGPPGPQGPPGD 1278 Score = 58.5 bits (140), Expect = 1e-08 Identities = 43/131 (32%), Positives = 44/131 (33%), Gaps = 63/131 (48%) Query: 245 LPGPPGLPGGQ--------------------GPPGSPGPKGSPG---------------- 268 LPGPPG PG GPPG PGP G PG Sbjct: 1147 LPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLH 1206 Query: 269 ------FPGMPGPPGQPGPRGSMGPMG---------------------PSPDLSHIKQGR 301 PG PGPPG PGPRG G G SPD+ G Sbjct: 1207 TAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGP 1266 Query: 302 RGPVGPPGAPG 312 GP GP G PG Sbjct: 1267 PGPPGPQGPPG 1277 Score = 57.4 bits (137), Expect = 2e-08 Identities = 39/99 (39%), Positives = 45/99 (45%), Gaps = 24/99 (24%) Query: 250 GLPGGQGPPGSPGP---------KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ- 299 GLPG GPPG PG +GS F G+ GPPG PGP G G + S + + Sbjct: 1146 GLPGPPGPPGLPGTSYEELLSLLRGSE-FRGIVGPPGPPGPPGIPGNVWSSISVEDLSSY 1204 Query: 300 ----GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334 G GPPG PG PGPRG PG G+ Sbjct: 1205 LHTAGLSFIPGPPGPPG---------PPGPRGPPGVSGA 1234 Score = 54.3 bits (129), Expect = 2e-07 Identities = 31/70 (44%), Positives = 35/70 (50%), Gaps = 10/70 (14%) Query: 274 GPPGQPGPRGSMGPM-------GPSPDLSHIKQ---GRRGPVGPPGAPGRDGSKGERGAP 323 GPPGQPGP+G G + DL Q +GP G G G G KG+RG Sbjct: 1399 GPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPA 1458 Query: 324 GPRGSPGPPG 333 GP G PGPPG Sbjct: 1459 GPPGHPGPPG 1468 Score = 54.3 bits (129), Expect = 2e-07 Identities = 31/72 (43%), Positives = 38/72 (52%), Gaps = 5/72 (6%) Query: 233 ITGDKVLASNTY--LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP 290 +T D + TY + GPPG +G G+PGPKG G G PG PG PGPRG G G Sbjct: 1422 VTADLMDFFQTYGAIQGPPGQ---KGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGD 1478 Query: 291 SPDLSHIKQGRR 302 D + + RR Sbjct: 1479 KGDQVYAGRRRR 1490 Score = 53.9 bits (128), Expect = 3e-07 Identities = 45/132 (34%), Positives = 47/132 (35%), Gaps = 60/132 (45%) Query: 251 LPGGQGPPGSPGPKG-------------------------SPGFPGMPGPPGQPGP---- 281 L G +GPPG PG G S G PG PGPPG PG Sbjct: 1104 LMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEE 1163 Query: 282 -----RGS--MGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSK-------------GERG 321 RGS G +GP GP GPPG PG S G Sbjct: 1164 LLSLLRGSEFRGIVGPP-----------GPPGPPGIPGNVWSSISVEDLSSYLHTAGLSF 1212 Query: 322 APGPRGSPGPPG 333 PGP G PGPPG Sbjct: 1213 IPGPPGPPGPPG 1224 Score = 53.1 bits (126), Expect = 4e-07 Identities = 52/185 (28%), Positives = 63/185 (34%), Gaps = 84/185 (45%) Query: 240 ASNTYLPGPPGLPGGQGPPGSPGPKGSP-------------------GFPGMPGPPGQPG 280 +S Y+ GPPG PG GPPGS G G G PGPPG PG Sbjct: 986 SSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPG 1045 Query: 281 PRGSMGPMGPSPDLS----------------------------------------HIKQG 300 P ++ G + D S +++Q Sbjct: 1046 PVTTI--TGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQY 1103 Query: 301 RRGPVGPPGAPGRDG---------------------SKG-ERGAPGPRGSPGPPG-SFDF 337 GP GPPG PG G S G G PGP G PG PG S++ Sbjct: 1104 LMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEE 1163 Query: 338 LLLML 342 LL +L Sbjct: 1164 LLSLL 1168 Score = 46.2 bits (108), Expect = 5e-05 Identities = 48/158 (30%), Positives = 58/158 (36%), Gaps = 60/158 (37%) Query: 228 DLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPG---------------- 271 DL Y+ A +++PGPPG PPG PGP+G PG G Sbjct: 1200 DLSSYLH----TAGLSFIPGPPG------PPGPPGPRGPPGVSGALATYAAENSDSFRSE 1249 Query: 272 ----MPGPP------GQPGPRGSMGPMGPSPDL-------------SHIKQGRRGPV--- 305 + P G PGP G GP G S L SH RRG Sbjct: 1250 LISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSS 1309 Query: 306 ------GPPGAPGRDGSKGE-RGAPGPRGSP-GPPGSF 335 G G+ G G+ GE G GP G+ GP G + Sbjct: 1310 SMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGY 1347 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.140 0.455 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,516,479 Number of Sequences: 37866 Number of extensions: 1769500 Number of successful extensions: 65652 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 574 Number of HSP's successfully gapped in prelim test: 1056 Number of HSP's that attempted gapping in prelim test: 10814 Number of HSP's gapped (non-prelim): 12685 length of query: 406 length of database: 18,247,518 effective HSP length: 105 effective length of query: 301 effective length of database: 14,271,588 effective search space: 4295747988 effective search space used: 4295747988 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.