Search of human proteins with 38788274

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38788274 bromodomain PHD finger transcription factor isoform
1 [Homo sapiens]
         (2920 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38788274 bromodomain PHD finger transcription factor isoform ...  5816   0.0  
gi|38788260 bromodomain PHD finger transcription factor isoform ...  3516   0.0  
gi|169211979 PREDICTED: hypothetical protein [Homo sapiens]           142   4e-33
gi|239740940 PREDICTED: hypothetical protein XP_002344108 [Homo ...   142   4e-33
gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]             114   1e-24
gi|153791535 general control of amino acid synthesis 5-like 2 [H...   109   3e-23
gi|221139761 zinc finger protein 853 [Homo sapiens]                   106   4e-22
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            94   2e-18
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]            94   2e-18
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            93   3e-18
gi|116284392 mucin 2 precursor [Homo sapiens]                          92   1e-17
gi|148612882 cat eye syndrome chromosome region, candidate 2 [Ho...    89   8e-17
gi|91982772 mucin 17 [Homo sapiens]                                    88   1e-16
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              87   2e-16
gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 ...    84   2e-15
gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [...    84   2e-15
gi|46399200 testis-specific bromodomain protein [Homo sapiens]         84   2e-15
gi|46399198 testis-specific bromodomain protein [Homo sapiens]         84   2e-15
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo...    84   3e-15
gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]    83   3e-15
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    83   5e-15
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ...    83   5e-15
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    83   5e-15
gi|47419911 transcriptional intermediary factor 1 alpha isoform ...    82   6e-15
gi|47419909 transcriptional intermediary factor 1 alpha isoform ...    82   6e-15
gi|161019170 mucin 5AC [Homo sapiens]                                  82   8e-15
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        79   5e-14
gi|150170670 piccolo isoform 2 [Homo sapiens]                          79   7e-14
gi|150378539 piccolo isoform 1 [Homo sapiens]                          79   7e-14
gi|56549696 E1A binding protein p400 [Homo sapiens]                    79   9e-14

>gi|38788274 bromodomain PHD finger transcription factor isoform 1
            [Homo sapiens]
          Length = 2920

 Score = 5816 bits (15087), Expect = 0.0
 Identities = 2920/2920 (100%), Positives = 2920/2920 (100%)

Query: 1    MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAP 60
            MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAP
Sbjct: 1    MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAP 60

Query: 61   KTRLSSPRGGSSSRRKPPPPPPAPPSTSAPGRGGRGGGGGRTGGGGGGGHLARTTAARRA 120
            KTRLSSPRGGSSSRRKPPPPPPAPPSTSAPGRGGRGGGGGRTGGGGGGGHLARTTAARRA
Sbjct: 61   KTRLSSPRGGSSSRRKPPPPPPAPPSTSAPGRGGRGGGGGRTGGGGGGGHLARTTAARRA 120

Query: 121  VNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME 180
            VNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
Sbjct: 121  VNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME 180

Query: 181  DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPN 240
            DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPN
Sbjct: 181  DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPN 240

Query: 241  EHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDT 300
            EHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDT
Sbjct: 241  EHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDT 300

Query: 301  SNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK 360
            SNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
Sbjct: 301  SNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK 360

Query: 361  IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPP 420
            IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPP
Sbjct: 361  IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPP 420

Query: 421  LEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIIE 480
            LEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIIE
Sbjct: 421  LEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIIE 480

Query: 481  EDTENENEKKIWYYSTKVQLAELIDCLDKDYWEAELCKILEEMREEIHRHMDITEDLTNK 540
            EDTENENEKKIWYYSTKVQLAELIDCLDKDYWEAELCKILEEMREEIHRHMDITEDLTNK
Sbjct: 481  EDTENENEKKIWYYSTKVQLAELIDCLDKDYWEAELCKILEEMREEIHRHMDITEDLTNK 540

Query: 541  ARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKDKNETENDSKDAEKNREEFEDQ 600
            ARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKDKNETENDSKDAEKNREEFEDQ
Sbjct: 541  ARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKDKNETENDSKDAEKNREEFEDQ 600

Query: 601  SLEKDSDDKTPDDDPEQGKSEVGDFKSEKSNGELSESPGAGKGASGSTRIITRLRNPDSK 660
            SLEKDSDDKTPDDDPEQGKSEVGDFKSEKSNGELSESPGAGKGASGSTRIITRLRNPDSK
Sbjct: 601  SLEKDSDDKTPDDDPEQGKSEVGDFKSEKSNGELSESPGAGKGASGSTRIITRLRNPDSK 660

Query: 661  LSQLKSQQVAAAAHEANKLFKEGKEVLVVNSQGEISRLSTKKEVIMKGNINNYFKLGQEG 720
            LSQLKSQQVAAAAHEANKLFKEGKEVLVVNSQGEISRLSTKKEVIMKGNINNYFKLGQEG
Sbjct: 661  LSQLKSQQVAAAAHEANKLFKEGKEVLVVNSQGEISRLSTKKEVIMKGNINNYFKLGQEG 720

Query: 721  KYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTL 780
            KYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTL
Sbjct: 721  KYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTL 780

Query: 781  RLTITQLENNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIW 840
            RLTITQLENNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIW
Sbjct: 781  RLTITQLENNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIW 840

Query: 841  RESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPVKHQVWKQKGEEY 900
            RESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPVKHQVWKQKGEEY
Sbjct: 841  RESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPVKHQVWKQKGEEY 900

Query: 901  RVTGYGGWSWISKTHVYRFVPKLPGNTNVNYRKSLEGTKNNMDENMDESDKRKCSRSPKK 960
            RVTGYGGWSWISKTHVYRFVPKLPGNTNVNYRKSLEGTKNNMDENMDESDKRKCSRSPKK
Sbjct: 901  RVTGYGGWSWISKTHVYRFVPKLPGNTNVNYRKSLEGTKNNMDENMDESDKRKCSRSPKK 960

Query: 961  IKIEPDSEKDEVKGSDAAKGADQNEMDISKITEKKDQDVKELLDSDSDKPCKEEPMEVDD 1020
            IKIEPDSEKDEVKGSDAAKGADQNEMDISKITEKKDQDVKELLDSDSDKPCKEEPMEVDD
Sbjct: 961  IKIEPDSEKDEVKGSDAAKGADQNEMDISKITEKKDQDVKELLDSDSDKPCKEEPMEVDD 1020

Query: 1021 DMKTESHVNCQESSQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIKQFTLEEKQRLE 1080
            DMKTESHVNCQESSQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIKQFTLEEKQRLE
Sbjct: 1021 DMKTESHVNCQESSQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIKQFTLEEKQRLE 1080

Query: 1081 KIKLEGGIKGIGKTSTNSSKNLSESPVITKAKEGCQSDSMRQEQSPNANNDQPEDLIQGC 1140
            KIKLEGGIKGIGKTSTNSSKNLSESPVITKAKEGCQSDSMRQEQSPNANNDQPEDLIQGC
Sbjct: 1081 KIKLEGGIKGIGKTSTNSSKNLSESPVITKAKEGCQSDSMRQEQSPNANNDQPEDLIQGC 1140

Query: 1141 SESDSSVLRMSDPSHTTNKLYPKDRVLDDVSIRSPETKCPKQNSIENDIEEKVSDLASRG 1200
            SESDSSVLRMSDPSHTTNKLYPKDRVLDDVSIRSPETKCPKQNSIENDIEEKVSDLASRG
Sbjct: 1141 SESDSSVLRMSDPSHTTNKLYPKDRVLDDVSIRSPETKCPKQNSIENDIEEKVSDLASRG 1200

Query: 1201 QEPSKSKTKGNDFFIDDSKLASADDIGTLICKNKKPLIQEESDTIVSSSKSALHSSVPKS 1260
            QEPSKSKTKGNDFFIDDSKLASADDIGTLICKNKKPLIQEESDTIVSSSKSALHSSVPKS
Sbjct: 1201 QEPSKSKTKGNDFFIDDSKLASADDIGTLICKNKKPLIQEESDTIVSSSKSALHSSVPKS 1260

Query: 1261 TNDRDATPLSRAMDFEGKLGCDSESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFR 1320
            TNDRDATPLSRAMDFEGKLGCDSESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFR
Sbjct: 1261 TNDRDATPLSRAMDFEGKLGCDSESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFR 1320

Query: 1321 TREQDVEVLEPLKCELVSGESTGNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIK 1380
            TREQDVEVLEPLKCELVSGESTGNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIK
Sbjct: 1321 TREQDVEVLEPLKCELVSGESTGNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIK 1380

Query: 1381 LKNTTDKKNNENRESEKKGQRTSTFQINGKDNKPKIYLKGECLKEISESRVVSGNVEPKV 1440
            LKNTTDKKNNENRESEKKGQRTSTFQINGKDNKPKIYLKGECLKEISESRVVSGNVEPKV
Sbjct: 1381 LKNTTDKKNNENRESEKKGQRTSTFQINGKDNKPKIYLKGECLKEISESRVVSGNVEPKV 1440

Query: 1441 NNINKIIPENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDS 1500
            NNINKIIPENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDS
Sbjct: 1441 NNINKIIPENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDS 1500

Query: 1501 LETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSND 1560
            LETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSND
Sbjct: 1501 LETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSND 1560

Query: 1561 FIDENGLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENC 1620
            FIDENGLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENC
Sbjct: 1561 FIDENGLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENC 1620

Query: 1621 AKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSK 1680
            AKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSK
Sbjct: 1621 AKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSK 1680

Query: 1681 EYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREV 1740
            EYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREV
Sbjct: 1681 EYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREV 1740

Query: 1741 PYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKA 1800
            PYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKA
Sbjct: 1741 PYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKA 1800

Query: 1801 PPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRK 1860
            PPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRK
Sbjct: 1801 PPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRK 1860

Query: 1861 GLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRL 1920
            GLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRL
Sbjct: 1861 GLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRL 1920

Query: 1921 EQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQ 1980
            EQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQ
Sbjct: 1921 EQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQ 1980

Query: 1981 NKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTS 2040
            NKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTS
Sbjct: 1981 NKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTS 2040

Query: 2041 GSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQ 2100
            GSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQ
Sbjct: 2041 GSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQ 2100

Query: 2101 PVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHG 2160
            PVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHG
Sbjct: 2101 PVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHG 2160

Query: 2161 GNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATT 2220
            GNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATT
Sbjct: 2161 GNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATT 2220

Query: 2221 ASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQ 2280
            ASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQ
Sbjct: 2221 ASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQ 2280

Query: 2281 PQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSP 2340
            PQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSP
Sbjct: 2281 PQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSP 2340

Query: 2341 VRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSS 2400
            VRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSS
Sbjct: 2341 VRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSS 2400

Query: 2401 TQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQ 2460
            TQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQ
Sbjct: 2401 TQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQ 2460

Query: 2461 SGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIE 2520
            SGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIE
Sbjct: 2461 SGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIE 2520

Query: 2521 IKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILD 2580
            IKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILD
Sbjct: 2521 IKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILD 2580

Query: 2581 KIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIE 2640
            KIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIE
Sbjct: 2581 KIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIE 2640

Query: 2641 VQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLS 2700
            VQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLS
Sbjct: 2641 VQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLS 2700

Query: 2701 TPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCD 2760
            TPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCD
Sbjct: 2701 TPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCD 2760

Query: 2761 RCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAH 2820
            RCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAH
Sbjct: 2761 RCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAH 2820

Query: 2821 KMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYY 2880
            KMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYY
Sbjct: 2821 KMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYY 2880

Query: 2881 NPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAS 2920
            NPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAS
Sbjct: 2881 NPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAS 2920


>gi|38788260 bromodomain PHD finger transcription factor isoform 2
            [Homo sapiens]
          Length = 2903

 Score = 3516 bits (9118), Expect = 0.0
 Identities = 1813/1983 (91%), Positives = 1851/1983 (93%), Gaps = 42/1983 (2%)

Query: 573  PEETEK--DKNETENDSKDAEKNREEFEDQSLEKDSDDKTPD--DDPEQGKSE------- 621
            PEE  K  + + T   +   + N E     S    S  ++    DDPE G+ E       
Sbjct: 684  PEEPNKTCESSNTSATTTSIQPNLENSNSSSELNSSQSESAKAADDPENGERESHTPVSI 743

Query: 622  ----VGDFKSEKSNGELSESPGAGKGASGSTRIITRLRNPDSKLSQLKSQQVAAAAHEAN 677
                VGDFKSEKSNGELSESPGAGKGASGSTRIITRLRNPDSKLSQLKSQQVAAAAHEAN
Sbjct: 744  QEEIVGDFKSEKSNGELSESPGAGKGASGSTRIITRLRNPDSKLSQLKSQQVAAAAHEAN 803

Query: 678  KLFKEGKEVLVVNSQGEISRLSTKKEVIMKGNINNYFKLGQEGKYRVYHNQYSTNSFALN 737
            KLFKEGKEVLVVNSQGEISRLSTKKEVIMKGNINNYFKLGQEGKYRVYHNQYSTNSFALN
Sbjct: 804  KLFKEGKEVLVVNSQGEISRLSTKKEVIMKGNINNYFKLGQEGKYRVYHNQYSTNSFALN 863

Query: 738  KHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLENNIPSSFLH 797
            KHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLENNIPSSFLH
Sbjct: 864  KHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLENNIPSSFLH 923

Query: 798  PNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIER 857
            PNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIER
Sbjct: 924  PNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIER 983

Query: 858  EEKEKVKKKEKKQEEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVY 917
            EEKEKVKKKEKKQEEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVY
Sbjct: 984  EEKEKVKKKEKKQEEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVY 1043

Query: 918  RFVPKLPGNTNVNYRKSLEGTKNNMDENMDESDKRKCSRSPKKIKIEPDSEKDEVKGSDA 977
            RFVPKLPGNTNVNYRKSLEGTKNNMDENMDESDKRKCSRSPKKIKIEPDSEKDEVKGSDA
Sbjct: 1044 RFVPKLPGNTNVNYRKSLEGTKNNMDENMDESDKRKCSRSPKKIKIEPDSEKDEVKGSDA 1103

Query: 978  AKGADQNEMDISKITEKKDQDVKELLDSDSDKPCKEEPMEVDDDMKTESHVNCQESSQVD 1037
            AKGADQNEMDISKITEKKDQDVKELLDSDSDKPCKEEPMEVDDDMKTESHVNCQESSQVD
Sbjct: 1104 AKGADQNEMDISKITEKKDQDVKELLDSDSDKPCKEEPMEVDDDMKTESHVNCQESSQVD 1163

Query: 1038 VVNVSEGFHLRTSYKKKTKSSKLDGLLERRIKQFTLEEKQRLEKIKLEGGIKGIGKTSTN 1097
            VVNVSEGFHLRTSYKKKTKSSKLDGLLERRIKQFTLEEKQRLEKIKLEGGIKGIGKTSTN
Sbjct: 1164 VVNVSEGFHLRTSYKKKTKSSKLDGLLERRIKQFTLEEKQRLEKIKLEGGIKGIGKTSTN 1223

Query: 1098 SSKNLSESPVITKAKEGCQSDSMRQEQSPNANNDQPEDLIQGCSESDSSVLRMSDPSHTT 1157
            SSKNLSESPVITKAKEGCQSDSMRQEQSPNANNDQPEDLIQGCSESDSSVLRMSDPSHTT
Sbjct: 1224 SSKNLSESPVITKAKEGCQSDSMRQEQSPNANNDQPEDLIQGCSESDSSVLRMSDPSHTT 1283

Query: 1158 NKLYPKDRVLDDVSIRSPETKCPKQNSIENDIEEKVSDLASRGQEPSKSKTKGNDFFIDD 1217
            NKLYPKDRVLDDVSIRSPETKCPKQNSIENDIEEKVSDLASRGQEPSKSKTKGNDFFIDD
Sbjct: 1284 NKLYPKDRVLDDVSIRSPETKCPKQNSIENDIEEKVSDLASRGQEPSKSKTKGNDFFIDD 1343

Query: 1218 SKLASADDIGTLICKNKKPLIQEESDTIVSSSKSALHSSVPKSTNDRDATPLSRAMDFEG 1277
            SKLASADDIGTLICKNKKPLIQEESDTIVSSSKSALHSSVPKSTNDRDATPLSRAMDFEG
Sbjct: 1344 SKLASADDIGTLICKNKKPLIQEESDTIVSSSKSALHSSVPKSTNDRDATPLSRAMDFEG 1403

Query: 1278 KLGCDSESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLEPLKCELV 1337
            KLGCDSESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLEPLKCELV
Sbjct: 1404 KLGCDSESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLEPLKCELV 1463

Query: 1338 SGESTGNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNNENRESEK 1397
            SGESTGNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNNENRESEK
Sbjct: 1464 SGESTGNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNNENRESEK 1523

Query: 1398 KGQRTSTFQINGKDNKPKIYLKGECLKEISESRVVSGNVEPKVNNINKIIPENDIKSLTV 1457
            KGQRTSTFQINGKDNKPKIYLKGECLKEISESRVVSGNVEPKVNNINKIIPENDIKSLTV
Sbjct: 1524 KGQRTSTFQINGKDNKPKIYLKGECLKEISESRVVSGNVEPKVNNINKIIPENDIKSLTV 1583

Query: 1458 KESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTT 1517
            KESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTT
Sbjct: 1584 KESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTT 1643

Query: 1518 PSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNG 1577
            PSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNG
Sbjct: 1644 PSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNG 1703

Query: 1578 ESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLST 1637
            ESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLST
Sbjct: 1704 ESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLST 1763

Query: 1638 PSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPK 1697
            PSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPK
Sbjct: 1764 PSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPK 1823

Query: 1698 KTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYP 1757
            KTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYP
Sbjct: 1824 KTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYP 1883

Query: 1758 SPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEIT 1817
            SPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEIT
Sbjct: 1884 SPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEIT 1943

Query: 1818 TTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQ 1877
            TTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQ
Sbjct: 1944 TTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQ 2003

Query: 1878 TGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTS 1937
            TGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTS
Sbjct: 2004 TGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTS 2063

Query: 1938 STTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQS 1997
            STTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQS
Sbjct: 2064 STTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQS 2123

Query: 1998 NSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQI 2057
            NSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQI
Sbjct: 2124 NSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQI 2183

Query: 2058 RPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPG 2117
            RPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPG
Sbjct: 2184 RPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPG 2243

Query: 2118 QKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTG 2177
            QKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTG
Sbjct: 2244 QKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTG 2303

Query: 2178 QLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGE 2237
            QLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGE
Sbjct: 2304 QLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGE 2363

Query: 2238 QRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQP 2297
            QRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQP
Sbjct: 2364 QRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQP 2423

Query: 2298 EVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPS 2357
            EVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPS
Sbjct: 2424 EVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPS 2483

Query: 2358 QLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSS 2417
            QLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQV      +             
Sbjct: 2484 QLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVVMKHNAVIE----------- 2532

Query: 2418 PSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQ 2477
                   ++Q +    A  +  Q++ V +Q+   ++ +I  ++    ++ K       ++
Sbjct: 2533 ------HLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRK-------RE 2579

Query: 2478 SSAVQTHQIQNVVTVQAASVQEQLQ-RVQQLRDQQQKKKQQQIEIKRE--HTLQASNQSE 2534
             S  Q    QN   + A   + + Q R + L+ +    K  QIE++ E    L+   + +
Sbjct: 2580 ESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKD 2639

Query: 2535 IIQ 2537
            ++Q
Sbjct: 2640 LMQ 2642



 Score = 1291 bits (3341), Expect = 0.0
 Identities = 627/648 (96%), Positives = 630/648 (97%), Gaps = 3/648 (0%)

Query: 1   MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAP 60
           MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAP
Sbjct: 1   MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAP 60

Query: 61  KTRLSSPRGGSSSRRKPPPPPPAPPSTSAPGRGGRGGGGGRTGGGGGGGHLARTTAARRA 120
           KTRLSSPRGGSSSRRKPPPPPPAPPSTSAPGRGGRGGGGGRTGGGGGGGHLARTTAARRA
Sbjct: 61  KTRLSSPRGGSSSRRKPPPPPPAPPSTSAPGRGGRGGGGGRTGGGGGGGHLARTTAARRA 120

Query: 121 VNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME 180
           VNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME
Sbjct: 121 VNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME 180

Query: 181 DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPN 240
           DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPN
Sbjct: 181 DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPN 240

Query: 241 EHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDT 300
           EHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDT
Sbjct: 241 EHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDT 300

Query: 301 SNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK 360
           SNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK
Sbjct: 301 SNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENK 360

Query: 361 IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPP 420
           IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPP
Sbjct: 361 IKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPP 420

Query: 421 LEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIIE 480
           LEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIIE
Sbjct: 421 LEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIIE 480

Query: 481 EDTENENEKKIWYYSTKVQLAELIDCLDKDYWEAELCKILEEMREEIHRHMDITEDLTNK 540
           EDTENENEKKIWYYSTKVQLAELIDCLDKDYWEAELCKILEEMREEIHRHMDITEDLTNK
Sbjct: 481 EDTENENEKKIWYYSTKVQLAELIDCLDKDYWEAELCKILEEMREEIHRHMDITEDLTNK 540

Query: 541 ARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKDKNETENDSKDAEKNREEFEDQ 600
           ARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKDKNETENDSKDAEKNREEFEDQ
Sbjct: 541 ARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKDKNETENDSKDAEKNREEFEDQ 600

Query: 601 SLEKDSDDKTPDDDPEQGKSEVGDFKSEKSNGELSESPGAGKGASGST 648
           SLEKDSDDKTPDDDPEQGKSE      +K N   S S   G   + +T
Sbjct: 601 SLEKDSDDKTPDDDPEQGKSEEPTEVGDKGN---SVSANLGDNTTNAT 645



 Score =  836 bits (2159), Expect = 0.0
 Identities = 507/920 (55%), Positives = 569/920 (61%), Gaps = 75/920 (8%)

Query: 2020 QQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQS-TLGKAII 2078
            QQ     + +  TV     TS +  TTS         I P   V+  P+  S T G  ++
Sbjct: 2040 QQAKKRLEQQKPTVIATSTTSPTSSTTST--------ISPAQKVMVAPISGSVTTGTKMV 2091

Query: 2079 RTPVMVQPGAP---------QQVMTQIIRGQPVSTAVSAPNTVSST-PGQKSLTSATSTS 2128
             T  +  P            Q   T + +GQ  S  V     V    P     +  T TS
Sbjct: 2092 LTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTS 2151

Query: 2129 NIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTV 2188
                +A+   RP       T +  +Q+  G     G+TV+     Q+T    +I   V V
Sbjct: 2152 FQPRTATVTIRPNTSGSGGTTSN-SQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMV 2210

Query: 2189 LPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQ 2248
             PG  QQ+M   +    V   +  P   ++T    + T+ ++T+     Q  +   P+ Q
Sbjct: 2211 QPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTS---NIQSSASQPPRPQ 2267

Query: 2249 VHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSH 2308
              Q K L  AQ + +       Q      Q Q QT  Q    P+  T      Q  + + 
Sbjct: 2268 QGQVK-LTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAA 2326

Query: 2309 VPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTP----SQLSPGQQ 2364
            +P+        +     A  +   +     +        Q+++ P         L P Q 
Sbjct: 2327 MPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQS 2386

Query: 2365 SQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSS--PSRPQ 2422
            S V    +QP   QP       +Q QPQ+QPQ  +  +  +  +   Q TVSS  PS  Q
Sbjct: 2387 SSVGPAEAQPQTAQPS------AQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQ 2440

Query: 2423 -LQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAV 2481
                Q  +PQV A  Q Q  VQ                          Q P+++Q  S  
Sbjct: 2441 PTHAQSSKPQVAAQSQPQSNVQG-------------------------QSPVRVQSPSQT 2475

Query: 2482 QTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEI-IQKQV 2540
            +             S   QL   QQ   Q Q    Q I I+   +LQ  +Q +   Q QV
Sbjct: 2476 RIRP----------STPSQLSPGQQ--SQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQV 2523

Query: 2541 VMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVE 2600
            VMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVE
Sbjct: 2524 VMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVE 2583

Query: 2601 QKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQL 2660
            QKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQL
Sbjct: 2584 QKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQL 2643

Query: 2661 AQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSS 2720
            AQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSS
Sbjct: 2644 AQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSS 2703

Query: 2721 SKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAEL 2780
            SKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAEL
Sbjct: 2704 SKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAEL 2763

Query: 2781 IDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYG 2840
            IDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYG
Sbjct: 2764 IDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYG 2823

Query: 2841 VIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQ 2900
            VIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQ
Sbjct: 2824 VIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQ 2883

Query: 2901 KLKGFKASRSHNNKLQSTAS 2920
            KLKGFKASRSHNNKLQSTAS
Sbjct: 2884 KLKGFKASRSHNNKLQSTAS 2903



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 18/34 (52%), Positives = 19/34 (55%), Gaps = 4/34 (11%)

Query: 2671 PPVTPAPPAP----PAPPPSPPPPPAVQHTGLLS 2700
            PP  PA PA     PAPPP PPPP +    GL S
Sbjct: 8    PPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRS 41



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 18/34 (52%), Positives = 19/34 (55%), Gaps = 4/34 (11%)

Query: 8    PPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRS 41
            PP  PA PA     PAPPP PPPP +    GL S
Sbjct: 2654 PPVTPAPPAP----PAPPPSPPPPPAVQHTGLLS 2683



 Score = 33.1 bits (74), Expect = 4.1
 Identities = 19/60 (31%), Positives = 33/60 (55%), Gaps = 1/60 (1%)

Query: 961  IKIEPDSEKDEVKGSDAAKGADQNEMDISKITEKKDQDVKELLDSDSDKPCKEEPMEVDD 1020
            +K   ++EKD+ +  + +K A++N  +    + +KD D K   D D ++   EEP EV D
Sbjct: 570  VKSPEETEKDKNETENDSKDAEKNREEFEDQSLEKDSDDK-TPDDDPEQGKSEEPTEVGD 628


>gi|169211979 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 168

 Score =  142 bits (359), Expect = 4e-33
 Identities = 76/128 (59%), Positives = 80/128 (62%), Gaps = 41/128 (32%)

Query: 2754 KFYIGCDRCQNWYHGRCVGILQ-----------------------------------SEA 2778
            +FYIGCD C NWY+G CVGI +                                   SEA
Sbjct: 29   RFYIGCDLCTNWYYGECVGIAEKEAKKMDVYICNDCKQAQEGSSEELYCICRTPAVTSEA 88

Query: 2779 ELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDY 2838
            ELIDEYVCPQCQSTEDAMTVLTPLTEKD E LKR      AHKMA PFLEPVDPNDAPDY
Sbjct: 89   ELIDEYVCPQCQSTEDAMTVLTPLTEKDDEELKR------AHKMARPFLEPVDPNDAPDY 142

Query: 2839 YGVIKEPM 2846
            YGVIKEP+
Sbjct: 143  YGVIKEPV 150


>gi|239740940 PREDICTED: hypothetical protein XP_002344108 [Homo
            sapiens]
          Length = 168

 Score =  142 bits (359), Expect = 4e-33
 Identities = 76/129 (58%), Positives = 80/129 (62%), Gaps = 41/129 (31%)

Query: 2753 SKFYIGCDRCQNWYHGRCVGILQ-----------------------------------SE 2777
            S+FYIGCD C NWY+G CVGI +                                   SE
Sbjct: 28   SRFYIGCDLCTNWYYGECVGIAEKEAKKMDVYICNDCKWAQEDSSEELYCICRTPAVTSE 87

Query: 2778 AELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPD 2837
            AELIDEYVCPQCQSTED MTVLTPLTEKD E LKR      AHKMA PFLEPVDPNDAPD
Sbjct: 88   AELIDEYVCPQCQSTEDVMTVLTPLTEKDDEELKR------AHKMARPFLEPVDPNDAPD 141

Query: 2838 YYGVIKEPM 2846
            YYGVIKEP+
Sbjct: 142  YYGVIKEPV 150


>gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]
          Length = 832

 Score =  114 bits (286), Expect = 1e-24
 Identities = 48/97 (49%), Positives = 69/97 (71%)

Query: 2807 YEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEF 2866
            Y  LK +L+ +++H+ AWPF+EPV   +AP YY VI+ PMDL TM ER++ RYY     F
Sbjct: 729  YSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLF 788

Query: 2867 VADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLK 2903
            +AD+ ++F NC+ YNP +S +Y+CA +LE FF  K+K
Sbjct: 789  MADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIK 825


>gi|153791535 general control of amino acid synthesis 5-like 2 [Homo
            sapiens]
          Length = 837

 Score =  109 bits (273), Expect = 3e-23
 Identities = 50/97 (51%), Positives = 66/97 (68%)

Query: 2807 YEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEF 2866
            Y  LK +L  +++H  AWPF+EPV  ++APDYY VI+ P+DL TM ER++ RYY     F
Sbjct: 734  YTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLF 793

Query: 2867 VADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLK 2903
            VAD+ ++  NCR YNP DS + +CA  LE FF  KLK
Sbjct: 794  VADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLK 830



 Score = 37.7 bits (86), Expect = 0.17
 Identities = 33/110 (30%), Positives = 36/110 (32%), Gaps = 43/110 (39%)

Query: 8   PPKQPAAPAAERCAPAPPPPPPP---PTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRL 64
           P   PAA      +PAP P P P   P S PI                            
Sbjct: 8   PTPAPAAQPRPLQSPAPAPTPTPAPSPASAPI---------------------------- 39

Query: 65  SSPRGGSSSRRKPPPPPPAPPSTSAP-GRGGRGGGGGRTGGGGGGGHLAR 113
                        P P PAP   +AP G  G GG G  +GG G GG  AR
Sbjct: 40  -----------PTPTPAPAPAPAAAPAGSTGTGGPGVGSGGAGSGGDPAR 78



 Score = 34.3 bits (77), Expect = 1.9
 Identities = 23/78 (29%), Positives = 31/78 (39%), Gaps = 21/78 (26%)

Query: 2661 AQATAVAAPCPPVTPAP-PAP-----PAPPPSPPPPPAVQHTGLLST------------- 2701
            AQ   + +P P  TP P P+P     P P P+P P PA    G   T             
Sbjct: 14   AQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGTGGPGVGSGGAGSG 73

Query: 2702 --PTLPAASQKRKREEEK 2717
              P  P  SQ+++  + K
Sbjct: 74   GDPARPGLSQQQRASQRK 91



 Score = 32.3 bits (72), Expect = 7.0
 Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 1/44 (2%)

Query: 2660 LAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPT 2703
            +A+ +    P P   P P   PAP P+P P P+   +  + TPT
Sbjct: 1    MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPS-PASAPIPTPT 43


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score =  106 bits (264), Expect = 4e-22
 Identities = 122/486 (25%), Positives = 206/486 (42%), Gaps = 74/486 (15%)

Query: 2256 PPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQP 2315
            P   S   G +E+Q +        +PQ +  SP +P V            +S +  E +P
Sbjct: 39   PDTLSGGSGGSESQEEE-------EPQERNSSPQRPAVSAP-------VGASEIAEETRP 84

Query: 2316 THAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPI 2375
               +    Q+  Q +PQ   Q +   ++Q P         P Q    Q SQ+Q    Q +
Sbjct: 85   GQRELQLQQLEQQPEPQQQPQHE---QLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSV 141

Query: 2376 PIQP--------HTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQ 2427
              Q         H   Q+  Q Q Q Q ++Q   + L + Q   Q  +    + Q Q+Q+
Sbjct: 142  HHQELKPELQLMHQQQQLQPQ-QVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQE 200

Query: 2428 PQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQ 2487
             Q       QLQQQ Q+L Q +     Q Q QQ  + QQ +L L   +QQ   +Q   +Q
Sbjct: 201  QQLLQQQQEQLQQQ-QLLQQQEQLQQQQFQQQQEQLQQQQQLLL---LQQQGQLQQQLLQ 256

Query: 2488 NVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAV 2547
                      Q+Q Q  QQL +QQQ + QQQ+ ++++  LQ   Q +++Q+Q        
Sbjct: 257  ----------QQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQ------- 299

Query: 2548 IEHLKQKK-SMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQ 2606
             E L+Q++    P E EE + + +  ++M   L    + E+Q  +  +++E   Q+  +Q
Sbjct: 300  -EQLQQQQLQPPPLEPEEEEEVEL--ELMPVDLGSEQELEQQRQELERQQELERQQEQRQ 356

Query: 2607 NATKLSALLFKHKEQLRAEILKKRALLDKDLQIEV--------QEELKRDLKIKKEKDLM 2658
               KL   L + ++QL  +   ++ L  +++Q+E+        Q+E++ +L   + +  +
Sbjct: 357  LQLKLQEELQQLEQQLEQQ---QQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPELQL 413

Query: 2659 QLAQATAVAAPCPPVTPAPPAPPAPP-----------PSPPPPPAVQHTGLLSTPTLPAA 2707
            +L  A        P  PA     APP           P+   P  V   G   +  L  A
Sbjct: 414  ELVPAAGGGGAAVPGAPA-AVVVAPPGYVVVQELMVLPAVAAPAVVAIPGPAGSAALTPA 472

Query: 2708 SQKRKR 2713
             Q+R+R
Sbjct: 473  RQRRRR 478



 Score = 65.9 bits (159), Expect = 6e-10
 Identities = 76/350 (21%), Positives = 151/350 (43%), Gaps = 23/350 (6%)

Query: 2383 LQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQV 2442
            LQ    G P        S  + S  +   Q   SSP RP +       ++    +  Q+ 
Sbjct: 29   LQCLEDGGPGPDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRE 88

Query: 2443 QVLSQIQSQVVAQIQAQQSGVPQ-QIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQL 2501
              L Q++ Q   Q Q Q   + Q Q  L+L  Q QQ    Q  Q+Q     Q+   QE  
Sbjct: 89   LQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQ-EKHQSVHHQELK 147

Query: 2502 QRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAE 2561
              +Q +  QQQ + QQ  E +R    Q   Q++  Q+Q V++    ++   Q++ +   +
Sbjct: 148  PELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQ 207

Query: 2562 REENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQ 2621
            +E+ Q+  +  Q          +E+ Q  + ++++E ++Q++          LL + + Q
Sbjct: 208  QEQLQQQQLLQQ----------QEQLQQQQFQQQQEQLQQQQ--------QLLLLQQQGQ 249

Query: 2622 LRAEIL-KKRALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAP 2680
            L+ ++L +++A L + L  + Q +L++ L +++++ L Q  Q   +      +      P
Sbjct: 250  LQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQP 309

Query: 2681 PAPPPSPPPPPAVQ--HTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKM 2728
            P   P       ++     L S   L    Q+ +R++E +   + ++ ++
Sbjct: 310  PPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQL 359



 Score = 55.5 bits (132), Expect = 8e-07
 Identities = 62/247 (25%), Positives = 106/247 (42%), Gaps = 22/247 (8%)

Query: 2237 EQRQSKLSPQMQV--HQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQ 2294
            EQ Q++ + + QV   Q++     Q   +   + +    Q   Q Q Q Q Q   Q + Q
Sbjct: 175  EQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQ 234

Query: 2295 TQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPS 2354
             Q   Q Q  +      + Q    Q  + Q+  Q   Q   Q Q  + +Q   Q +++  
Sbjct: 235  LQ---QQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQ--QEQLQQQ 289

Query: 2355 TPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQP---QSQPQVQSSTQTLSSGQTLN 2411
               QL   QQ Q+Q    QP P++P    ++  +  P    S+ +++   Q L   Q L 
Sbjct: 290  QQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELE 349

Query: 2412 QVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQV---VAQIQAQQSGVPQQIK 2468
            +       + QLQ++  +       QL+QQ Q L Q + Q+     ++ AQQ    Q+++
Sbjct: 350  R----QQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQ----QEVQ 401

Query: 2469 LQL-PIQ 2474
            L+L P+Q
Sbjct: 402  LELTPVQ 408


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 94.0 bits (232), Expect = 2e-18
 Identities = 193/978 (19%), Positives = 338/978 (34%), Gaps = 70/978 (7%)

Query: 1476 NERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDME 1535
            +E  ++ T+    +++  EG+   ++ T  S   + S   +  + +C E + +  V    
Sbjct: 371  SETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTV 430

Query: 1536 IETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVITEVTTMTSTV 1595
             ET+       S IT    S+         G           E+K        TT  S  
Sbjct: 431  FETTTAS-TEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNT 489

Query: 1596 ATESKTVIKV--------EKGDKQTVVS---------STENCAKSTVTTTTTTVTKLSTP 1638
              E+ TV  +         +G + T VS         STE    +TV+TT +  T +ST 
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVST- 548

Query: 1639 STGGSVDIISVKEQSKTVVTTTVTDSLT--TTGGTLVTSMTVSKEYSTRDKVKLMKFSRP 1696
             TG      S +    T V+TT  ++ T  T G     + T   E +T      +  +  
Sbjct: 549  -TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTT------VSTADS 601

Query: 1697 KKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPY 1756
            + T + TA        T  S+ +     + +    + +G   E    +        +   
Sbjct: 602  ENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGS--ETTTVSTTDSETTMVSTT 659

Query: 1757 PSPRPTFGITWRYRLQTVKSLAGVSLMLR----LLWASLRWDDMAAKAPPGGGTTRTETS 1812
             S R T   T      TV +    + +          S+   +    +  G  TT T T 
Sbjct: 660  GSER-TITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTE 718

Query: 1813 ETEITTTEII--KRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPK 1870
             +EITT  I   +       G  +     +         T  ET T       ++     
Sbjct: 719  GSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIM 778

Query: 1871 RPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIAT 1930
              ET   +      T V+    ++  +  F E  E   A     +          T+ A+
Sbjct: 779  GSETTMASTIGSETTKVSTASSKMTTV--FTENSETTIASTTASETTTVSTAGSETIPAS 836

Query: 1931 STTSPTSSTTSTISPAQKVMVAPISGSVTT-----GTKMVLTTKVGSPATVTFQQNKNFH 1985
            +  S T++TTST     +   A   GS TT      ++    T +GS  T    +     
Sbjct: 837  TAGSETTTTTST--EGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS--- 891

Query: 1986 QTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGT 2045
            +T  T  +  ++ +   +  +       S+TG+   T ++    T T +   +   +  T
Sbjct: 892  ETTTTSTEGSETTTASTEGSEIT---TVSTTGSETTTASTEGSETTTASTEGSELTTVST 948

Query: 2046 TSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTA 2105
            T +  +    +     TV     + +T   A   T  +   G+  +  T  I G   +T 
Sbjct: 949  TGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGS--ETTTASIEGSETTTV 1006

Query: 2106 VSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGL 2165
             S  +  ++     + T+ TST   +++       +   V  T ++ T  T    G++  
Sbjct: 1007 SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT--TTSTEGSETT 1064

Query: 2166 TVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTT 2225
            TV   G   TT     +        G G      A  + T   ++     TTA+T  +  
Sbjct: 1065 TVSTTGSETTTASTADLETTTVSTSGSGTTTASTA-GSETTTVYITGSKTTTASTEGSEA 1123

Query: 2226 TTVSTTAA--GTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQT 2283
            TTVSTT++   T     S+++       + T      S    + A    A  ++    +T
Sbjct: 1124 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183

Query: 2284 QPQSPAQPEVQTQPEVQTQTTVSSHVPSE---AQPTHAQSSKPQVAAQSQ-------PQS 2333
               S A  E  T     ++TT +S   SE   A  T +++S P  A            +S
Sbjct: 1184 TTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSES 1243

Query: 2334 NVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQI-PSQGQPQ 2392
             +   + +   + S T    +T S  + G  +   T +S    +   T + I P    P 
Sbjct: 1244 TIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPM 1303

Query: 2393 SQPQVQSSTQTLSSGQTL 2410
            S  +   +  T SS  T+
Sbjct: 1304 SGTRTTGTRLTASSSVTM 1321



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 231/1190 (19%), Positives = 421/1190 (35%), Gaps = 154/1190 (12%)

Query: 1197 ASRGQEPSKSKTKGNDFFI------DDSKLASAD-DIGTLICKNKKPL----IQEESDTI 1245
            ++ G EP+ + T G++  +      + +K+++A  ++ T+     + +    +  E+ T+
Sbjct: 287  STTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV 346

Query: 1246 VSSSKSALHSSVPKSTNDRDATPLSRAMDFEGKLGCDSESNSTLENSSDTVSIQDSSEED 1305
             ++      +S+  S    D+T  S       + G ++ + ST  + + TVS   S    
Sbjct: 347  STTGSETTTASIMGSETSTDSTTGSETTTASTE-GSETTTASTEGSEATTVSTTGSETTT 405

Query: 1306 MIVQNSNESISEQFRTREQDVEVLEPLKCELVSGESTGNCEDRLPVKGTEANGKKPSQQK 1365
            + + +S  + +    T   ++  +     E  +  + G+    + +  T  +    +  +
Sbjct: 406  VSITDSETTTT---CTEGSEMTAVSTTVFETTTASTEGS---EITIASTSDSETTTASTE 459

Query: 1366 KLEERPVNKCSDQIKLKNTTDKKNNENRESEKKGQRTSTFQINGKDNKPKIYLKGECLKE 1425
              E   V     + K   TT    +E   +   G  T+T    G D             E
Sbjct: 460  GSETTTVTTAGSETKTAYTT---GSETTTASNTGLETTTVFTIGSDTTT-------ASTE 509

Query: 1426 ISESRVVSGNVEPKVNNINKIIPENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKS 1485
             SE+  VS     ++  ++    EN   S T  E+          +     E  ++ T+ 
Sbjct: 510  GSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETT--------TVSTTGLETTTTSTEG 560

Query: 1486 HLLSSSDAEG--NYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSEV-- 1541
              +++    G     DS E   +T  S +   TT  ++    N+     D E  ++    
Sbjct: 561  SEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG 620

Query: 1542 KKVTSSPITSEEESNLSNDFIDENGLPINKNENV---NGESKRKTVITEVTTMTSTVATE 1598
             + T++  TS E +  S +  +   +    +E        S+R    TE +  T+  AT 
Sbjct: 621  SETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATG 680

Query: 1599 SKTVIKVEKGDKQTV-VSSTENCAKSTV-TTTTTTVT---KLSTPSTGGSVDIISVKEQS 1653
            S+T +  E     TV ++ +E    ST  + TTTT T   +++T S  GS    +  E S
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740

Query: 1654 KTVVTTT---VTDSLTTTGGTLVTSMTVSKEYSTR----DKVKLMKFSRPKKTRSGTALP 1706
            +T   +T    T S +TTG    T+ T S E +       +  +      + T+  TA  
Sbjct: 741  ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800

Query: 1707 SYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGI- 1765
                  T++S+ +I      +   ++  G    +P     ++         S   T    
Sbjct: 801  KMTTVFTENSETTIASTTASETTTVSTAGS-ETIPASTAGSETTTTTSTEGSETTTASTE 859

Query: 1766 ---TWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTTEII 1822
               T     ++ ++    ++      AS    +    +  G  TT   T  +EITT    
Sbjct: 860  GSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITT---- 915

Query: 1823 KRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPE--TPKQTGP 1880
                                    V  T  ET T   +G  ++    +  E  T   TG 
Sbjct: 916  ------------------------VSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 951

Query: 1881 VIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTV----IATSTTSPT 1936
              I   V+ E  E   +               E         +  T       T+T S T
Sbjct: 952  ETIT--VSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSST 1009

Query: 1937 SSTTSTIS-PAQKVMVAPISGSVTT-----GTKMVLTTKVGSPATVTFQQNKNFHQTFAT 1990
             S T+T+S    +  +    GS TT     G++       GS  T T  +         T
Sbjct: 1010 GSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTT 1069

Query: 1991 WVKQGQSNSGVVQ---VQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGT-- 2045
              +   +++  ++   V     G   +ST  S+ T       T + T   +T GS  T  
Sbjct: 1070 GSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYI---TGSKTTTASTEGSEATTV 1126

Query: 2046 -TSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVST 2104
             T++S+  T       MT + T + ++T   + I +       A  +  T    G   +T
Sbjct: 1127 STTSSETTTASTTGSEMTTVFTTVSETTT-VSTIGSEATTSSAAGSEATTTSTEGSETTT 1185

Query: 2105 AVSA--PNTVSSTPGQKSLTSATS---TSNIQSSASQPPRPQQG-------------QVK 2146
            A +A    T +ST G ++ T++TS   T+   ++ S+   P                   
Sbjct: 1186 ASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTI 1245

Query: 2147 LTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTV 2206
             + A L        G++  TV I   G T           T +      L +A   + ++
Sbjct: 1246 ASTASLEPTATSLTGSETTTVSITASGATAAS--------TTVSSTTFVLTKAT--DVSI 1295

Query: 2207 QRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPA 2266
            Q    TP++ T TT +  T + S T A   +   S  S         T+P    ++ G  
Sbjct: 1296 QPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAAS--------HTVPGIVLNTSGLG 1347

Query: 2267 EAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPE-----VQTQTTVSSHVPS 2311
             +    +  ++    +T   S  +P   T  E     + T T   SH P+
Sbjct: 1348 TSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPT 1397



 Score = 79.7 bits (195), Expect = 4e-14
 Identities = 182/1001 (18%), Positives = 340/1001 (33%), Gaps = 99/1001 (9%)

Query: 1481 SETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSE 1540
            SET + L+ +S+         ET  +T     +QTT  S S  E  + +         S 
Sbjct: 23   SETTTILIKASETTTASTAGSET--TTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSS 80

Query: 1541 VKKVTSSPITSEEESNLSNDFIDENGLPINKNEN-----VNGESKRKTVITEVTTMTSTV 1595
                T++   +  E+ +S    +   + I   E      +  E+   +  +  TT+TST 
Sbjct: 81   AGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTA 140

Query: 1596 ATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKT 1655
             +E+ TV  V  G + T    T   A S  T  +TT ++++T  T GS  I      S+T
Sbjct: 141  GSETTTVSTV--GSETT----TAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSET 194

Query: 1656 VVTTTV---TDSLTTTGGTLVTSMTVSKEYSTRDKV--KLMKFSRPKKTRSGTALPSYRK 1710
               +T    T +++TTG    T+ T   E +    +  +  K S      + +   S   
Sbjct: 195  TTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETT 254

Query: 1711 FVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPAL--------DIWPYPSPRPT 1762
              +    ++      D     A   G          ++P +         +     P  T
Sbjct: 255  AASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETT 314

Query: 1763 FGITWRYRLQTVKSLAGVSLMLRLL---------------WASLRWDDMAAKAPPGGGTT 1807
               T    + TV +    ++    +                AS+   + +  +  G  TT
Sbjct: 315  KVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETT 374

Query: 1808 --RTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSS 1865
               TE SET   +TE  +   V   G  +            V  T  ET T   +G   +
Sbjct: 375  TASTEGSETTTASTEGSEATTVSTTGSET----------TTVSITDSETTTTCTEGSEMT 424

Query: 1866 ALRPKRPETPKQT--GPVII--------ETWVAEEELELWEIRAFAERVEKEKAQAVEQQ 1915
            A+     ET   +  G  I          T  + E  E   +       +       E  
Sbjct: 425  AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETT 484

Query: 1916 AKKRLEQQKPTVIATSTTSPTSS-----TTSTISPAQKVMVAPISGS-----VTTGTKMV 1965
                   +  TV    + + T+S     TT+  +   ++      GS      TTG++  
Sbjct: 485  TASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETT 544

Query: 1966 LTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTS 2025
              +  G   T T  +         T  +    ++       +  G   +ST  S+ T  S
Sbjct: 545  TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST-------EGSGTTAASTAGSETTTVS 597

Query: 2026 FQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQ 2085
                  T     ++  +  +T+ S+  T        T   T   ++T          MV 
Sbjct: 598  TADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS 657

Query: 2086 PGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLT---SATSTSNIQSSASQPPRPQQ 2142
                ++ +T     +  + + +   T  ST G  + T   + + T+ + ++ S+      
Sbjct: 658  TTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTST 717

Query: 2143 GQVKLTMAQLT---QLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQA 2199
               ++T A +T     T    G++  T   +G  +TT       +  T      +  M +
Sbjct: 718  EGSEITTASITGSETTTASTEGSETTTASTEG-SETTSASTTGSETTTASTTSSETTMAS 776

Query: 2200 AMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQ 2259
             M + T          T  +TAS+  TTV T      E  ++ ++      +  T+  A 
Sbjct: 777  IMGSETTMASTIGSETTKVSTASSKMTTVFT------ENSETTIA-STTASETTTVSTAG 829

Query: 2260 SSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQ 2319
            S ++  + A  +T   ++    +T   S    E  T     ++TT ++ + SE      +
Sbjct: 830  SETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTE 889

Query: 2320 SSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQP 2379
             S+    +    ++         + + S T    +T S  + G ++   +T    +    
Sbjct: 890  GSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS--TEGSETTTASTEGSELTTVS 947

Query: 2380 HT---SLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSS 2417
             T   ++ + ++G   +      S  T +S       TVS+
Sbjct: 948  TTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVST 988



 Score = 73.2 bits (178), Expect = 4e-12
 Identities = 189/933 (20%), Positives = 316/933 (33%), Gaps = 86/933 (9%)

Query: 1506 STKESDSTQTTTPSASCPESNSVNQVEDMEIETS--EVKKVTSSPITSEEESNLSNDFID 1563
            +TK S +   TT S +  E+ + +  ED E  T+  E  K T++  T  E +  S     
Sbjct: 234  TTKVSTAGSETTVSTAGSETTAAS-TEDSETNTAFTEDSKTTTASTTGFETTAAST---- 288

Query: 1564 ENGLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENCAKS 1623
              G        +  E+   + I   TT  ST ++E  TV        +T+ +ST     +
Sbjct: 289  -TGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAA---GSETIRASTVGSETT 344

Query: 1624 TVTTT---TTTVT----KLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTT--TGGTLVT 1674
            TV+TT   TTT +    + ST ST GS    +  E S+T   +T     TT  T G+  T
Sbjct: 345  TVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETT 404

Query: 1675 SMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARK 1734
            +++++   +T    +  + +    T   T   S     T+ S+ +I    + +    + +
Sbjct: 405  TVSITDSETTTTCTEGSEMTAVSTTVFETTTAS-----TEGSEITIASTSDSETTTASTE 459

Query: 1735 GG-IREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRW 1793
            G     V       K A       +     G+       TV ++   +       AS   
Sbjct: 460  GSETTTVTTAGSETKTAYTTGSETTTASNTGL----ETTTVFTIGSDTTT-----ASTEG 510

Query: 1794 DDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKE 1853
             +  A +  G   T   T  +E TT                            V  T  E
Sbjct: 511  SETTAVSATGSEMTTVSTEGSENTT----------------------------VSTTGSE 542

Query: 1854 TPTPQRKGLRSSALRPKRPE-TPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAV 1912
            T T    GL ++    +  E T   T      T   E         A +E      A + 
Sbjct: 543  TTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADS- 601

Query: 1913 EQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGS 1972
            E       + +  +   T + + T+STTS+ +       +  +   TT ++  + +  GS
Sbjct: 602  ENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGS 661

Query: 1973 PATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLG--IIPSSTGTSQQTFTSFQPRT 2030
              T+T  +        AT  +   S  G       + G      ST  S+ T TS +   
Sbjct: 662  ERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSE 721

Query: 2031 ATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQ 2090
             T      +  +  +T  S+  T        T   T   ++T          M      +
Sbjct: 722  ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSE 781

Query: 2091 QVMTQIIRGQ--PVSTAVSAPNTVSSTPGQKSLTSAT-STSNIQSSASQPPRPQQGQVKL 2147
              M   I  +   VSTA S   TV +   + ++ S T S +   S+A     P       
Sbjct: 782  TTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAS----- 836

Query: 2148 TMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNG-TV 2206
            T    T  T    G++  T   +G   TT   +      T     G +   A+     T 
Sbjct: 837  TAGSETTTTTSTEGSETTTASTEGSETTTASTE--SSETTTATTIGSETTTASTEGSETT 894

Query: 2207 QRFLFTPLATTATTASTTTTTVSTTAA--GTGEQRQSKLSPQMQVHQDKTLPPAQSSSVG 2264
                     TTA+T  +  TTVSTT +   T     S+ +       + T      S   
Sbjct: 895  TTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETI 954

Query: 2265 PAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQ 2324
               A+            +T   S A  E  T     ++TT +S   SE     +  S+  
Sbjct: 955  TVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETT 1014

Query: 2325 VAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQ 2384
              + +  ++ +           S+T    +  S+ +    +  +TTT+     +  T   
Sbjct: 1015 TVSTTGTETTITS------TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST 1068

Query: 2385 IPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSS 2417
              S+    S   ++++T + S   T    T  S
Sbjct: 1069 TGSETTTASTADLETTTVSTSGSGTTTASTAGS 1101



 Score = 62.4 bits (150), Expect = 6e-09
 Identities = 212/1135 (18%), Positives = 374/1135 (32%), Gaps = 168/1135 (14%)

Query: 1338 SGESTGNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKN----TTDKKNNENR 1393
            +  +TG+    + +K +E      +  +     P    +  + +      TT    +EN 
Sbjct: 17   TASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENT 76

Query: 1394 ESEKKGQRTSTFQINGKDNKPKIYLKGECLKEISESRVVSGNVEPKVNNINKIIPENDIK 1453
                 G  T+T  + G +    +   G     +S    ++G     V+ +     E    
Sbjct: 77   TVSSAGSGTTTASMAGSETT--VSTAGSETTTVS----ITGTETTMVSAMGS---ETTTN 127

Query: 1454 SLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDST 1513
            S T  E+ +             +   S  T    + S        DS  T  ST  S+ T
Sbjct: 128  STTSSETTVT------------STAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMT 175

Query: 1514 -------QTTTPSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSNDFIDENG 1566
                   +T TPS +  E+ +V+         S     T++  T+  E+  ++      G
Sbjct: 176  TVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTM----G 231

Query: 1567 LPINKNENVNGESKRKTVITEVTTM------TSTVATE-SKTVIKVEKGDKQTVVSST-- 1617
                K      E+   T  +E T        T+T  TE SKT      G + T  S+T  
Sbjct: 232  SETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGS 291

Query: 1618 ENCAKSTVTTTTTTV-------TKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGG 1670
            E    ST+ + TT         TK+ST S+  +    +  E  +     + T +++TTG 
Sbjct: 292  EPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGS 351

Query: 1671 TLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKK 1730
               T+  +  E ST              T S T   S     T+ S+ +       +   
Sbjct: 352  ETTTASIMGSETST-----------DSTTGSETTTAS-----TEGSETTTASTEGSEATT 395

Query: 1731 LARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTV----KSLAGVSLMLRL 1786
            ++  G                      S   T  IT      T     +  A  + +   
Sbjct: 396  VSTTG----------------------SETTTVSITDSETTTTCTEGSEMTAVSTTVFET 433

Query: 1787 LWASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIG 1846
              AS    ++   +     TT   T  +E TT           Y   SE           
Sbjct: 434  TTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE--------TTT 485

Query: 1847 VPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEK 1906
               T  ET T    G  ++    +  ET   +      T V+ E  E   +         
Sbjct: 486  ASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTT 545

Query: 1907 EKAQAVEQQAKKRLEQQKPTVIATSTTSPTSST-------TSTISPAQKVMVAPISGSVT 1959
                 +E         +  TV  T   + T ST        ST       +    S + T
Sbjct: 546  VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 1960 TGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTS 2019
              T    TT   +  + T   +    +T  T   +G   + V     +   +   ST  S
Sbjct: 606  ASTADSETTSASTTGSETTTASTTSSET-TTASTEGSETTTVSTTDSETTMV---STTGS 661

Query: 2020 QQTFTSFQ-PRTATVT-----IRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTL 2073
            ++T TS +   T TV+        +T GSG TT +   ITG +     T        ST 
Sbjct: 662  ERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS---ITGSETTKVSTTGSETTTTSTE 718

Query: 2074 GKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVS--APNTVSSTPGQKSLTSATSTSNIQ 2131
            G                ++ T  I G   +TA +  +  T +ST G ++ +++T+ S   
Sbjct: 719  G---------------SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETT 763

Query: 2132 SSASQPPRPQQGQV---KLTMAQL--TQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGV 2186
            ++++         +   + TMA    ++ T+    +  +T V     +TT       +  
Sbjct: 764  TASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETT 823

Query: 2187 TVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQ 2246
            TV     +                 T  A+TA + +TTTT+   +   T     S+ +  
Sbjct: 824  TVSTAGSE-----------------TIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 2247 MQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVS 2306
                 + T      S    A  +      ++    +T   S    E+ T     ++TT +
Sbjct: 867  STESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTA 926

Query: 2307 SHVPSEAQPTHAQSSKPQVAAQSQPQS---NVQGQSPVRVQS-PSQTRIRPSTPSQLSPG 2362
            S   SE      + S+    + +  ++   + +G     V +  S+T    +  S+ +  
Sbjct: 927  STEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTV 986

Query: 2363 QQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSS 2417
              +  +TTT+    I+   +  + S G   +      +  T++S +     TV++
Sbjct: 987  STAGSETTTAS---IEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTT 1038



 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 207/1129 (18%), Positives = 373/1129 (33%), Gaps = 162/1129 (14%)

Query: 973  KGSDAAKGADQNEMDISKITEKKDQDVKELLDSDSDKPCKE-EPMEVDDDMKTESHVNCQ 1031
            +GS+    + +     +  T   +     + DS++   C E   M        E+     
Sbjct: 379  EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438

Query: 1032 ESSQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIKQFTLEEKQRLEKIKLEGG-IKG 1090
            E S++ + + S+      S +    ++      E +    T  E        LE   +  
Sbjct: 439  EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFT 498

Query: 1091 IGKTSTNSSKNLSESPVITKAKEGCQSDSMRQEQSPNANNDQPEDLIQGCSESDSSVLRM 1150
            IG  +T +S   SE+  ++    G +  ++  E S N             S + S    +
Sbjct: 499  IGSDTTTASTEGSETTAVSAT--GSEMTTVSTEGSENTT----------VSTTGSETTTV 546

Query: 1151 SDPSHTTNKLYPKDRVLDDVSIRSPETKCPKQNSIENDIEEKVSDLASRGQEPSKSKTKG 1210
            S     T     +   +  VS    ET     +S E       S   S     S + ++ 
Sbjct: 547  STTGLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 1211 NDFFIDDSKLASADDIGTLICKNKKPLIQEESDTIVSSSKSALHSSVPKSTNDRDATPLS 1270
                  DS+  SA   G+             S+T  +S++ +  ++V  ST D + T +S
Sbjct: 604  TTASTADSETTSASTTGS----ETTTASTTSSETTTASTEGSETTTV--STTDSETTMVS 657

Query: 1271 RAMDFEGKLGCDSESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLE 1330
                        SE   T    S+T ++  +  E  +        +E   T    +   E
Sbjct: 658  TT---------GSERTITSTEGSETTTVSATGSETTVS-------TEGSGTTTVSITGSE 701

Query: 1331 PLKCELVSGESTGNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNN 1390
              K      E+T    +   +      G + +             S +     T   + +
Sbjct: 702  TTKVSTTGSETTTTSTEGSEITTASITGSETTT-----------ASTEGSETTTASTEGS 750

Query: 1391 ENRESEKKGQRTSTFQINGKDNKPKIYLKGECLKEI---SESRVVSGNVEPKVNNINKII 1447
            E   +   G  T+T      +      +  E        SE+  VS     K+  +    
Sbjct: 751  ETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS-TASSKMTTVFTEN 809

Query: 1448 PENDIKSLTVKESAIRPFINGDVI-------------MEDFNERNSSETKSHLLSSSDAE 1494
             E  I S T  E+        + I               + +E  ++ T+    +++  E
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTE 869

Query: 1495 GNYRDSLETLPS---TKESDSTQTTTPSASCPESNSVNQVEDMEIETSEV--KKVTSSPI 1549
             +   +  T+ S   T  ++ ++TTT S    E+ + +  E  EI T      + T++  
Sbjct: 870  SSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAS-TEGSEITTVSTTGSETTTAST 928

Query: 1550 TSEEESNLSNDFIDENGLPINKNEN--VNGESKRKTVITEV---TTMTSTVATESKTVIK 1604
               E +  S +  +   +    +E   V+ E    T +T +   TT  ST  +E+ TV  
Sbjct: 929  EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVST 988

Query: 1605 VE--------KGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTV 1656
                      +G + T VSST +   +TV+TT T  T  ST   G     ++      T 
Sbjct: 989  AGSETTTASIEGSETTTVSSTGS-ETTTVSTTGTETTITST--EGSETTTVTTAGSETTA 1045

Query: 1657 VTTTVTDSLTT-TGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKS 1715
            V TT +++ TT T G+  T+++ +   +T      ++ +    + SGT   S     T  
Sbjct: 1046 VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAS-----TAG 1100

Query: 1716 SKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVK 1775
            S+ +   +        + +G           A          +   T G        TV 
Sbjct: 1101 SETTTVYITGSKTTTASTEGS---------EATTVSTTSSETTTASTTGSEMTTVFTTVS 1151

Query: 1776 SLAGVSLM-LRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRS 1834
                VS +      +S    +    +  G  TT   T+ +E TT                
Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS-------------- 1197

Query: 1835 EYCIRKIICPIGVPETPKETPTPQRKG--LRSSALRPKRPETPKQTGPVIIETWVAEEEL 1892
                              ET T    G    ++        TP   G      ++   E 
Sbjct: 1198 --------------TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSES 1243

Query: 1893 ELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATST-----TSPTSSTTSTISPAQ 1947
             +                ++E  A      +  TV  T++     ++  SSTT  ++ A 
Sbjct: 1244 TI------------ASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKAT 1291

Query: 1948 KVMVAPI-----SGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQ---GQSNS 1999
             V + PI     SG+ TTGT++  ++ V     + F  +   H      +     G S  
Sbjct: 1292 DVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTM 1351

Query: 2000 GVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSN 2048
            G         G+  ++  T + T ++FQ  T  V++  NT     T +N
Sbjct: 1352 GASST-TSAHGVRTTTGSTREPTSSTFQ-ETGPVSMGTNTVSMSHTPTN 1398



 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 101/536 (18%), Positives = 184/536 (34%), Gaps = 54/536 (10%)

Query: 1929 ATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTF 1988
            A  + + T+STT + +    +  +  + + T G++    +  GS  T+          T 
Sbjct: 10   AAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS 69

Query: 1989 ATWVKQ---GQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGT 2045
                +      + SG             S+ G+   T +     T  V+   + + +  T
Sbjct: 70   TAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNST 129

Query: 2046 TSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPG--------APQQVMTQII 2097
            TS+   +T        TV     + +T   A   T      G        A  + +T   
Sbjct: 130  TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPST 189

Query: 2098 RGQ---PVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQ 2154
             G     VSTA S   TVS+T  +   T+  ST++ +++A+     +  +V    ++ T 
Sbjct: 190  AGSETTTVSTAGSETTTVSTTGSE---TTTASTAHSETTAASTMGSETTKVSTAGSETTV 246

Query: 2155 LTQGH-------GGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQ 2207
             T G          ++  T   +    TT              G  +  M + M + T  
Sbjct: 247  STAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTG-SEPTMASTMGSETTM 305

Query: 2208 RFLFTPLATTATTASTTTTTV----------------STTAAGTGEQRQ------SKLSP 2245
                 P  T  +TAS+  TTV                +TT + TG +        S+ S 
Sbjct: 306  ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365

Query: 2246 QMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTV 2305
                  + T    + S    A  +   A   +    +T   S    E  T     ++ T 
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 2306 SSHVPSEAQPTHAQSSKPQVAAQSQPQ---SNVQGQSPVRVQSP-SQTRIRPSTPSQLSP 2361
             S    E      + S+  +A+ S  +   ++ +G     V +  S+T+   +T S+ + 
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485

Query: 2362 GQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSS 2417
               + ++TTT   I     T+    ++G   +      S  T  S +     TVS+
Sbjct: 486  ASNTGLETTTVFTIGSDTTTA---STEGSETTAVSATGSEMTTVSTEGSENTTVST 538



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 76/412 (18%), Positives = 144/412 (34%), Gaps = 26/412 (6%)

Query: 2012 IPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQS 2071
            +  + G++  T ++    T T+ I+ + + +  T  +      P       V  +  + +
Sbjct: 7    VAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEIT 66

Query: 2072 TLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQ 2131
            T   A      +   G+     +       VSTA S   TVS T  + ++ SA  +    
Sbjct: 67   TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126

Query: 2132 SSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPG 2191
            +S +        +  +T    ++ T         T       +TT       +  TV   
Sbjct: 127  NSTTS------SETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 2192 PGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAA--GTGEQRQSKLSPQMQV 2249
              + +  +   + T          TT +TA + TTTVSTT +   T     S+ +    +
Sbjct: 181  GSETITPSTAGSET----------TTVSTAGSETTTVSTTGSETTTASTAHSETTAASTM 230

Query: 2250 HQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHV 2309
              + T      S    + A  +T   S +   +T        +  T      +TT +S  
Sbjct: 231  GSETTKVSTAGSETTVSTAGSETTAASTE-DSETNTAFTEDSKTTTASTTGFETTAASTT 289

Query: 2310 PSEAQPTHAQSSKPQVAAQSQPQS---NVQGQSPVRVQSPSQTRIRPST-PSQLSPGQQS 2365
             SE        S+  +A+   P++   +        V +     IR ST  S+ +    +
Sbjct: 290  GSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTT 349

Query: 2366 QVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSS 2417
              +TTT+  +  +  T     + G   +    + S  T +S +     TVS+
Sbjct: 350  GSETTTASIMGSETSTD---STTGSETTTASTEGSETTTASTEGSEATTVST 398



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 45/202 (22%), Positives = 73/202 (36%), Gaps = 15/202 (7%)

Query: 2216 TTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQP 2275
            T A  A + TTT STT + T        +  ++  +  T   A S +  P+    QT   
Sbjct: 6    TVAPAAGSNTTTASTTGSET-------TTILIKASETTTASTAGSETTTPSPTGSQTTIV 58

Query: 2276 SAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNV 2335
            S      T   S A  E  T     + TT +S   SE   + A S    V+      + V
Sbjct: 59   SISGSEIT-TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117

Query: 2336 QGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQP 2395
                       S+T    +T S+ +    +  +TTT   +  +  T+    S+    S  
Sbjct: 118  SAMG-------SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTT 170

Query: 2396 QVQSSTQTLSSGQTLNQVTVSS 2417
              + +T   +  +T+   T  S
Sbjct: 171  GSEMTTVFTAGSETITPSTAGS 192


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 94.0 bits (232), Expect = 2e-18
 Identities = 193/978 (19%), Positives = 338/978 (34%), Gaps = 70/978 (7%)

Query: 1476 NERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDME 1535
            +E  ++ T+    +++  EG+   ++ T  S   + S   +  + +C E + +  V    
Sbjct: 371  SETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTV 430

Query: 1536 IETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVITEVTTMTSTV 1595
             ET+       S IT    S+         G           E+K        TT  S  
Sbjct: 431  FETTTAS-TEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNT 489

Query: 1596 ATESKTVIKV--------EKGDKQTVVS---------STENCAKSTVTTTTTTVTKLSTP 1638
              E+ TV  +         +G + T VS         STE    +TV+TT +  T +ST 
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVST- 548

Query: 1639 STGGSVDIISVKEQSKTVVTTTVTDSLT--TTGGTLVTSMTVSKEYSTRDKVKLMKFSRP 1696
             TG      S +    T V+TT  ++ T  T G     + T   E +T      +  +  
Sbjct: 549  -TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTT------VSTADS 601

Query: 1697 KKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPY 1756
            + T + TA        T  S+ +     + +    + +G   E    +        +   
Sbjct: 602  ENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGS--ETTTVSTTDSETTMVSTT 659

Query: 1757 PSPRPTFGITWRYRLQTVKSLAGVSLMLR----LLWASLRWDDMAAKAPPGGGTTRTETS 1812
             S R T   T      TV +    + +          S+   +    +  G  TT T T 
Sbjct: 660  GSER-TITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTE 718

Query: 1813 ETEITTTEII--KRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPK 1870
             +EITT  I   +       G  +     +         T  ET T       ++     
Sbjct: 719  GSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIM 778

Query: 1871 RPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIAT 1930
              ET   +      T V+    ++  +  F E  E   A     +          T+ A+
Sbjct: 779  GSETTMASTIGSETTKVSTASSKMTTV--FTENSETTIASTTASETTTVSTAGSETIPAS 836

Query: 1931 STTSPTSSTTSTISPAQKVMVAPISGSVTT-----GTKMVLTTKVGSPATVTFQQNKNFH 1985
            +  S T++TTST     +   A   GS TT      ++    T +GS  T    +     
Sbjct: 837  TAGSETTTTTST--EGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS--- 891

Query: 1986 QTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGT 2045
            +T  T  +  ++ +   +  +       S+TG+   T ++    T T +   +   +  T
Sbjct: 892  ETTTTSTEGSETTTASTEGSEIT---TVSTTGSETTTASTEGSETTTASTEGSELTTVST 948

Query: 2046 TSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTA 2105
            T +  +    +     TV     + +T   A   T  +   G+  +  T  I G   +T 
Sbjct: 949  TGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGS--ETTTASIEGSETTTV 1006

Query: 2106 VSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGL 2165
             S  +  ++     + T+ TST   +++       +   V  T ++ T  T    G++  
Sbjct: 1007 SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT--TTSTEGSETT 1064

Query: 2166 TVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTT 2225
            TV   G   TT     +        G G      A  + T   ++     TTA+T  +  
Sbjct: 1065 TVSTTGSETTTASTADLETTTVSTSGSGTTTASTA-GSETTTVYITGSKTTTASTEGSEA 1123

Query: 2226 TTVSTTAA--GTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQT 2283
            TTVSTT++   T     S+++       + T      S    + A    A  ++    +T
Sbjct: 1124 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183

Query: 2284 QPQSPAQPEVQTQPEVQTQTTVSSHVPSE---AQPTHAQSSKPQVAAQSQ-------PQS 2333
               S A  E  T     ++TT +S   SE   A  T +++S P  A            +S
Sbjct: 1184 TTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSES 1243

Query: 2334 NVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQI-PSQGQPQ 2392
             +   + +   + S T    +T S  + G  +   T +S    +   T + I P    P 
Sbjct: 1244 TIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPM 1303

Query: 2393 SQPQVQSSTQTLSSGQTL 2410
            S  +   +  T SS  T+
Sbjct: 1304 SGTRTTGTRLTASSSVTM 1321



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 231/1190 (19%), Positives = 421/1190 (35%), Gaps = 154/1190 (12%)

Query: 1197 ASRGQEPSKSKTKGNDFFI------DDSKLASAD-DIGTLICKNKKPL----IQEESDTI 1245
            ++ G EP+ + T G++  +      + +K+++A  ++ T+     + +    +  E+ T+
Sbjct: 287  STTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV 346

Query: 1246 VSSSKSALHSSVPKSTNDRDATPLSRAMDFEGKLGCDSESNSTLENSSDTVSIQDSSEED 1305
             ++      +S+  S    D+T  S       + G ++ + ST  + + TVS   S    
Sbjct: 347  STTGSETTTASIMGSETSTDSTTGSETTTASTE-GSETTTASTEGSEATTVSTTGSETTT 405

Query: 1306 MIVQNSNESISEQFRTREQDVEVLEPLKCELVSGESTGNCEDRLPVKGTEANGKKPSQQK 1365
            + + +S  + +    T   ++  +     E  +  + G+    + +  T  +    +  +
Sbjct: 406  VSITDSETTTT---CTEGSEMTAVSTTVFETTTASTEGS---EITIASTSDSETTTASTE 459

Query: 1366 KLEERPVNKCSDQIKLKNTTDKKNNENRESEKKGQRTSTFQINGKDNKPKIYLKGECLKE 1425
              E   V     + K   TT    +E   +   G  T+T    G D             E
Sbjct: 460  GSETTTVTTAGSETKTAYTT---GSETTTASNTGLETTTVFTIGSDTTT-------ASTE 509

Query: 1426 ISESRVVSGNVEPKVNNINKIIPENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKS 1485
             SE+  VS     ++  ++    EN   S T  E+          +     E  ++ T+ 
Sbjct: 510  GSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETT--------TVSTTGLETTTTSTEG 560

Query: 1486 HLLSSSDAEG--NYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSEV-- 1541
              +++    G     DS E   +T  S +   TT  ++    N+     D E  ++    
Sbjct: 561  SEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG 620

Query: 1542 KKVTSSPITSEEESNLSNDFIDENGLPINKNENV---NGESKRKTVITEVTTMTSTVATE 1598
             + T++  TS E +  S +  +   +    +E        S+R    TE +  T+  AT 
Sbjct: 621  SETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATG 680

Query: 1599 SKTVIKVEKGDKQTV-VSSTENCAKSTV-TTTTTTVT---KLSTPSTGGSVDIISVKEQS 1653
            S+T +  E     TV ++ +E    ST  + TTTT T   +++T S  GS    +  E S
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740

Query: 1654 KTVVTTT---VTDSLTTTGGTLVTSMTVSKEYSTR----DKVKLMKFSRPKKTRSGTALP 1706
            +T   +T    T S +TTG    T+ T S E +       +  +      + T+  TA  
Sbjct: 741  ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800

Query: 1707 SYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGI- 1765
                  T++S+ +I      +   ++  G    +P     ++         S   T    
Sbjct: 801  KMTTVFTENSETTIASTTASETTTVSTAGS-ETIPASTAGSETTTTTSTEGSETTTASTE 859

Query: 1766 ---TWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTTEII 1822
               T     ++ ++    ++      AS    +    +  G  TT   T  +EITT    
Sbjct: 860  GSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITT---- 915

Query: 1823 KRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPE--TPKQTGP 1880
                                    V  T  ET T   +G  ++    +  E  T   TG 
Sbjct: 916  ------------------------VSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS 951

Query: 1881 VIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTV----IATSTTSPT 1936
              I   V+ E  E   +               E         +  T       T+T S T
Sbjct: 952  ETIT--VSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSST 1009

Query: 1937 SSTTSTIS-PAQKVMVAPISGSVTT-----GTKMVLTTKVGSPATVTFQQNKNFHQTFAT 1990
             S T+T+S    +  +    GS TT     G++       GS  T T  +         T
Sbjct: 1010 GSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTT 1069

Query: 1991 WVKQGQSNSGVVQ---VQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGT-- 2045
              +   +++  ++   V     G   +ST  S+ T       T + T   +T GS  T  
Sbjct: 1070 GSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYI---TGSKTTTASTEGSEATTV 1126

Query: 2046 -TSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVST 2104
             T++S+  T       MT + T + ++T   + I +       A  +  T    G   +T
Sbjct: 1127 STTSSETTTASTTGSEMTTVFTTVSETTT-VSTIGSEATTSSAAGSEATTTSTEGSETTT 1185

Query: 2105 AVSA--PNTVSSTPGQKSLTSATS---TSNIQSSASQPPRPQQG-------------QVK 2146
            A +A    T +ST G ++ T++TS   T+   ++ S+   P                   
Sbjct: 1186 ASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTI 1245

Query: 2147 LTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTV 2206
             + A L        G++  TV I   G T           T +      L +A   + ++
Sbjct: 1246 ASTASLEPTATSLTGSETTTVSITASGATAAS--------TTVSSTTFVLTKAT--DVSI 1295

Query: 2207 QRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPA 2266
            Q    TP++ T TT +  T + S T A   +   S  S         T+P    ++ G  
Sbjct: 1296 QPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAAS--------HTVPGIVLNTSGLG 1347

Query: 2267 EAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPE-----VQTQTTVSSHVPS 2311
             +    +  ++    +T   S  +P   T  E     + T T   SH P+
Sbjct: 1348 TSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPT 1397



 Score = 79.7 bits (195), Expect = 4e-14
 Identities = 182/1001 (18%), Positives = 340/1001 (33%), Gaps = 99/1001 (9%)

Query: 1481 SETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSE 1540
            SET + L+ +S+         ET  +T     +QTT  S S  E  + +         S 
Sbjct: 23   SETTTILIKASETTTASTAGSET--TTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSS 80

Query: 1541 VKKVTSSPITSEEESNLSNDFIDENGLPINKNEN-----VNGESKRKTVITEVTTMTSTV 1595
                T++   +  E+ +S    +   + I   E      +  E+   +  +  TT+TST 
Sbjct: 81   AGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTA 140

Query: 1596 ATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKT 1655
             +E+ TV  V  G + T    T   A S  T  +TT ++++T  T GS  I      S+T
Sbjct: 141  GSETTTVSTV--GSETT----TAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSET 194

Query: 1656 VVTTTV---TDSLTTTGGTLVTSMTVSKEYSTRDKV--KLMKFSRPKKTRSGTALPSYRK 1710
               +T    T +++TTG    T+ T   E +    +  +  K S      + +   S   
Sbjct: 195  TTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETT 254

Query: 1711 FVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPAL--------DIWPYPSPRPT 1762
              +    ++      D     A   G          ++P +         +     P  T
Sbjct: 255  AASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETT 314

Query: 1763 FGITWRYRLQTVKSLAGVSLMLRLL---------------WASLRWDDMAAKAPPGGGTT 1807
               T    + TV +    ++    +                AS+   + +  +  G  TT
Sbjct: 315  KVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETT 374

Query: 1808 --RTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSS 1865
               TE SET   +TE  +   V   G  +            V  T  ET T   +G   +
Sbjct: 375  TASTEGSETTTASTEGSEATTVSTTGSET----------TTVSITDSETTTTCTEGSEMT 424

Query: 1866 ALRPKRPETPKQT--GPVII--------ETWVAEEELELWEIRAFAERVEKEKAQAVEQQ 1915
            A+     ET   +  G  I          T  + E  E   +       +       E  
Sbjct: 425  AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETT 484

Query: 1916 AKKRLEQQKPTVIATSTTSPTSS-----TTSTISPAQKVMVAPISGS-----VTTGTKMV 1965
                   +  TV    + + T+S     TT+  +   ++      GS      TTG++  
Sbjct: 485  TASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETT 544

Query: 1966 LTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTS 2025
              +  G   T T  +         T  +    ++       +  G   +ST  S+ T  S
Sbjct: 545  TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST-------EGSGTTAASTAGSETTTVS 597

Query: 2026 FQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQ 2085
                  T     ++  +  +T+ S+  T        T   T   ++T          MV 
Sbjct: 598  TADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS 657

Query: 2086 PGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLT---SATSTSNIQSSASQPPRPQQ 2142
                ++ +T     +  + + +   T  ST G  + T   + + T+ + ++ S+      
Sbjct: 658  TTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTST 717

Query: 2143 GQVKLTMAQLT---QLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQA 2199
               ++T A +T     T    G++  T   +G  +TT       +  T      +  M +
Sbjct: 718  EGSEITTASITGSETTTASTEGSETTTASTEG-SETTSASTTGSETTTASTTSSETTMAS 776

Query: 2200 AMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQ 2259
             M + T          T  +TAS+  TTV T      E  ++ ++      +  T+  A 
Sbjct: 777  IMGSETTMASTIGSETTKVSTASSKMTTVFT------ENSETTIA-STTASETTTVSTAG 829

Query: 2260 SSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQ 2319
            S ++  + A  +T   ++    +T   S    E  T     ++TT ++ + SE      +
Sbjct: 830  SETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTE 889

Query: 2320 SSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQP 2379
             S+    +    ++         + + S T    +T S  + G ++   +T    +    
Sbjct: 890  GSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS--TEGSETTTASTEGSELTTVS 947

Query: 2380 HT---SLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSS 2417
             T   ++ + ++G   +      S  T +S       TVS+
Sbjct: 948  TTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVST 988



 Score = 73.2 bits (178), Expect = 4e-12
 Identities = 189/933 (20%), Positives = 316/933 (33%), Gaps = 86/933 (9%)

Query: 1506 STKESDSTQTTTPSASCPESNSVNQVEDMEIETS--EVKKVTSSPITSEEESNLSNDFID 1563
            +TK S +   TT S +  E+ + +  ED E  T+  E  K T++  T  E +  S     
Sbjct: 234  TTKVSTAGSETTVSTAGSETTAAS-TEDSETNTAFTEDSKTTTASTTGFETTAAST---- 288

Query: 1564 ENGLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENCAKS 1623
              G        +  E+   + I   TT  ST ++E  TV        +T+ +ST     +
Sbjct: 289  -TGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAA---GSETIRASTVGSETT 344

Query: 1624 TVTTT---TTTVT----KLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTT--TGGTLVT 1674
            TV+TT   TTT +    + ST ST GS    +  E S+T   +T     TT  T G+  T
Sbjct: 345  TVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETT 404

Query: 1675 SMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARK 1734
            +++++   +T    +  + +    T   T   S     T+ S+ +I    + +    + +
Sbjct: 405  TVSITDSETTTTCTEGSEMTAVSTTVFETTTAS-----TEGSEITIASTSDSETTTASTE 459

Query: 1735 GG-IREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRW 1793
            G     V       K A       +     G+       TV ++   +       AS   
Sbjct: 460  GSETTTVTTAGSETKTAYTTGSETTTASNTGL----ETTTVFTIGSDTTT-----ASTEG 510

Query: 1794 DDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKE 1853
             +  A +  G   T   T  +E TT                            V  T  E
Sbjct: 511  SETTAVSATGSEMTTVSTEGSENTT----------------------------VSTTGSE 542

Query: 1854 TPTPQRKGLRSSALRPKRPE-TPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAV 1912
            T T    GL ++    +  E T   T      T   E         A +E      A + 
Sbjct: 543  TTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADS- 601

Query: 1913 EQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGS 1972
            E       + +  +   T + + T+STTS+ +       +  +   TT ++  + +  GS
Sbjct: 602  ENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGS 661

Query: 1973 PATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLG--IIPSSTGTSQQTFTSFQPRT 2030
              T+T  +        AT  +   S  G       + G      ST  S+ T TS +   
Sbjct: 662  ERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSE 721

Query: 2031 ATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQ 2090
             T      +  +  +T  S+  T        T   T   ++T          M      +
Sbjct: 722  ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSE 781

Query: 2091 QVMTQIIRGQ--PVSTAVSAPNTVSSTPGQKSLTSAT-STSNIQSSASQPPRPQQGQVKL 2147
              M   I  +   VSTA S   TV +   + ++ S T S +   S+A     P       
Sbjct: 782  TTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAS----- 836

Query: 2148 TMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNG-TV 2206
            T    T  T    G++  T   +G   TT   +      T     G +   A+     T 
Sbjct: 837  TAGSETTTTTSTEGSETTTASTEGSETTTASTE--SSETTTATTIGSETTTASTEGSETT 894

Query: 2207 QRFLFTPLATTATTASTTTTTVSTTAA--GTGEQRQSKLSPQMQVHQDKTLPPAQSSSVG 2264
                     TTA+T  +  TTVSTT +   T     S+ +       + T      S   
Sbjct: 895  TTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETI 954

Query: 2265 PAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQ 2324
               A+            +T   S A  E  T     ++TT +S   SE     +  S+  
Sbjct: 955  TVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETT 1014

Query: 2325 VAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQ 2384
              + +  ++ +           S+T    +  S+ +    +  +TTT+     +  T   
Sbjct: 1015 TVSTTGTETTITS------TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST 1068

Query: 2385 IPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSS 2417
              S+    S   ++++T + S   T    T  S
Sbjct: 1069 TGSETTTASTADLETTTVSTSGSGTTTASTAGS 1101



 Score = 62.4 bits (150), Expect = 6e-09
 Identities = 212/1135 (18%), Positives = 374/1135 (32%), Gaps = 168/1135 (14%)

Query: 1338 SGESTGNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKN----TTDKKNNENR 1393
            +  +TG+    + +K +E      +  +     P    +  + +      TT    +EN 
Sbjct: 17   TASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENT 76

Query: 1394 ESEKKGQRTSTFQINGKDNKPKIYLKGECLKEISESRVVSGNVEPKVNNINKIIPENDIK 1453
                 G  T+T  + G +    +   G     +S    ++G     V+ +     E    
Sbjct: 77   TVSSAGSGTTTASMAGSETT--VSTAGSETTTVS----ITGTETTMVSAMGS---ETTTN 127

Query: 1454 SLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDST 1513
            S T  E+ +             +   S  T    + S        DS  T  ST  S+ T
Sbjct: 128  STTSSETTVT------------STAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMT 175

Query: 1514 -------QTTTPSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSNDFIDENG 1566
                   +T TPS +  E+ +V+         S     T++  T+  E+  ++      G
Sbjct: 176  TVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTM----G 231

Query: 1567 LPINKNENVNGESKRKTVITEVTTM------TSTVATE-SKTVIKVEKGDKQTVVSST-- 1617
                K      E+   T  +E T        T+T  TE SKT      G + T  S+T  
Sbjct: 232  SETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGS 291

Query: 1618 ENCAKSTVTTTTTTV-------TKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGG 1670
            E    ST+ + TT         TK+ST S+  +    +  E  +     + T +++TTG 
Sbjct: 292  EPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGS 351

Query: 1671 TLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKK 1730
               T+  +  E ST              T S T   S     T+ S+ +       +   
Sbjct: 352  ETTTASIMGSETST-----------DSTTGSETTTAS-----TEGSETTTASTEGSEATT 395

Query: 1731 LARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTV----KSLAGVSLMLRL 1786
            ++  G                      S   T  IT      T     +  A  + +   
Sbjct: 396  VSTTG----------------------SETTTVSITDSETTTTCTEGSEMTAVSTTVFET 433

Query: 1787 LWASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIG 1846
              AS    ++   +     TT   T  +E TT           Y   SE           
Sbjct: 434  TTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE--------TTT 485

Query: 1847 VPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEK 1906
               T  ET T    G  ++    +  ET   +      T V+ E  E   +         
Sbjct: 486  ASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTT 545

Query: 1907 EKAQAVEQQAKKRLEQQKPTVIATSTTSPTSST-------TSTISPAQKVMVAPISGSVT 1959
                 +E         +  TV  T   + T ST        ST       +    S + T
Sbjct: 546  VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 1960 TGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTS 2019
              T    TT   +  + T   +    +T  T   +G   + V     +   +   ST  S
Sbjct: 606  ASTADSETTSASTTGSETTTASTTSSET-TTASTEGSETTTVSTTDSETTMV---STTGS 661

Query: 2020 QQTFTSFQ-PRTATVT-----IRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTL 2073
            ++T TS +   T TV+        +T GSG TT +   ITG +     T        ST 
Sbjct: 662  ERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS---ITGSETTKVSTTGSETTTTSTE 718

Query: 2074 GKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVS--APNTVSSTPGQKSLTSATSTSNIQ 2131
            G                ++ T  I G   +TA +  +  T +ST G ++ +++T+ S   
Sbjct: 719  G---------------SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETT 763

Query: 2132 SSASQPPRPQQGQV---KLTMAQL--TQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGV 2186
            ++++         +   + TMA    ++ T+    +  +T V     +TT       +  
Sbjct: 764  TASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETT 823

Query: 2187 TVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQ 2246
            TV     +                 T  A+TA + +TTTT+   +   T     S+ +  
Sbjct: 824  TVSTAGSE-----------------TIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 2247 MQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVS 2306
                 + T      S    A  +      ++    +T   S    E+ T     ++TT +
Sbjct: 867  STESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTA 926

Query: 2307 SHVPSEAQPTHAQSSKPQVAAQSQPQS---NVQGQSPVRVQS-PSQTRIRPSTPSQLSPG 2362
            S   SE      + S+    + +  ++   + +G     V +  S+T    +  S+ +  
Sbjct: 927  STEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTV 986

Query: 2363 QQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSS 2417
              +  +TTT+    I+   +  + S G   +      +  T++S +     TV++
Sbjct: 987  STAGSETTTAS---IEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTT 1038



 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 207/1129 (18%), Positives = 373/1129 (33%), Gaps = 162/1129 (14%)

Query: 973  KGSDAAKGADQNEMDISKITEKKDQDVKELLDSDSDKPCKE-EPMEVDDDMKTESHVNCQ 1031
            +GS+    + +     +  T   +     + DS++   C E   M        E+     
Sbjct: 379  EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438

Query: 1032 ESSQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIKQFTLEEKQRLEKIKLEGG-IKG 1090
            E S++ + + S+      S +    ++      E +    T  E        LE   +  
Sbjct: 439  EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFT 498

Query: 1091 IGKTSTNSSKNLSESPVITKAKEGCQSDSMRQEQSPNANNDQPEDLIQGCSESDSSVLRM 1150
            IG  +T +S   SE+  ++    G +  ++  E S N             S + S    +
Sbjct: 499  IGSDTTTASTEGSETTAVSAT--GSEMTTVSTEGSENTT----------VSTTGSETTTV 546

Query: 1151 SDPSHTTNKLYPKDRVLDDVSIRSPETKCPKQNSIENDIEEKVSDLASRGQEPSKSKTKG 1210
            S     T     +   +  VS    ET     +S E       S   S     S + ++ 
Sbjct: 547  STTGLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 1211 NDFFIDDSKLASADDIGTLICKNKKPLIQEESDTIVSSSKSALHSSVPKSTNDRDATPLS 1270
                  DS+  SA   G+             S+T  +S++ +  ++V  ST D + T +S
Sbjct: 604  TTASTADSETTSASTTGS----ETTTASTTSSETTTASTEGSETTTV--STTDSETTMVS 657

Query: 1271 RAMDFEGKLGCDSESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLE 1330
                        SE   T    S+T ++  +  E  +        +E   T    +   E
Sbjct: 658  TT---------GSERTITSTEGSETTTVSATGSETTVS-------TEGSGTTTVSITGSE 701

Query: 1331 PLKCELVSGESTGNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNN 1390
              K      E+T    +   +      G + +             S +     T   + +
Sbjct: 702  TTKVSTTGSETTTTSTEGSEITTASITGSETTT-----------ASTEGSETTTASTEGS 750

Query: 1391 ENRESEKKGQRTSTFQINGKDNKPKIYLKGECLKEI---SESRVVSGNVEPKVNNINKII 1447
            E   +   G  T+T      +      +  E        SE+  VS     K+  +    
Sbjct: 751  ETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS-TASSKMTTVFTEN 809

Query: 1448 PENDIKSLTVKESAIRPFINGDVI-------------MEDFNERNSSETKSHLLSSSDAE 1494
             E  I S T  E+        + I               + +E  ++ T+    +++  E
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTE 869

Query: 1495 GNYRDSLETLPS---TKESDSTQTTTPSASCPESNSVNQVEDMEIETSEV--KKVTSSPI 1549
             +   +  T+ S   T  ++ ++TTT S    E+ + +  E  EI T      + T++  
Sbjct: 870  SSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAS-TEGSEITTVSTTGSETTTAST 928

Query: 1550 TSEEESNLSNDFIDENGLPINKNEN--VNGESKRKTVITEV---TTMTSTVATESKTVIK 1604
               E +  S +  +   +    +E   V+ E    T +T +   TT  ST  +E+ TV  
Sbjct: 929  EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVST 988

Query: 1605 VE--------KGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTV 1656
                      +G + T VSST +   +TV+TT T  T  ST   G     ++      T 
Sbjct: 989  AGSETTTASIEGSETTTVSSTGS-ETTTVSTTGTETTITST--EGSETTTVTTAGSETTA 1045

Query: 1657 VTTTVTDSLTT-TGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKS 1715
            V TT +++ TT T G+  T+++ +   +T      ++ +    + SGT   S     T  
Sbjct: 1046 VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAS-----TAG 1100

Query: 1716 SKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVK 1775
            S+ +   +        + +G           A          +   T G        TV 
Sbjct: 1101 SETTTVYITGSKTTTASTEGS---------EATTVSTTSSETTTASTTGSEMTTVFTTVS 1151

Query: 1776 SLAGVSLM-LRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRS 1834
                VS +      +S    +    +  G  TT   T+ +E TT                
Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS-------------- 1197

Query: 1835 EYCIRKIICPIGVPETPKETPTPQRKG--LRSSALRPKRPETPKQTGPVIIETWVAEEEL 1892
                              ET T    G    ++        TP   G      ++   E 
Sbjct: 1198 --------------TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSES 1243

Query: 1893 ELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATST-----TSPTSSTTSTISPAQ 1947
             +                ++E  A      +  TV  T++     ++  SSTT  ++ A 
Sbjct: 1244 TI------------ASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKAT 1291

Query: 1948 KVMVAPI-----SGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQ---GQSNS 1999
             V + PI     SG+ TTGT++  ++ V     + F  +   H      +     G S  
Sbjct: 1292 DVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTM 1351

Query: 2000 GVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSN 2048
            G         G+  ++  T + T ++FQ  T  V++  NT     T +N
Sbjct: 1352 GASST-TSAHGVRTTTGSTREPTSSTFQ-ETGPVSMGTNTVSMSHTPTN 1398



 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 101/536 (18%), Positives = 184/536 (34%), Gaps = 54/536 (10%)

Query: 1929 ATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTF 1988
            A  + + T+STT + +    +  +  + + T G++    +  GS  T+          T 
Sbjct: 10   AAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS 69

Query: 1989 ATWVKQ---GQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGT 2045
                +      + SG             S+ G+   T +     T  V+   + + +  T
Sbjct: 70   TAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNST 129

Query: 2046 TSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPG--------APQQVMTQII 2097
            TS+   +T        TV     + +T   A   T      G        A  + +T   
Sbjct: 130  TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPST 189

Query: 2098 RGQ---PVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQ 2154
             G     VSTA S   TVS+T  +   T+  ST++ +++A+     +  +V    ++ T 
Sbjct: 190  AGSETTTVSTAGSETTTVSTTGSE---TTTASTAHSETTAASTMGSETTKVSTAGSETTV 246

Query: 2155 LTQGH-------GGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQ 2207
             T G          ++  T   +    TT              G  +  M + M + T  
Sbjct: 247  STAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTG-SEPTMASTMGSETTM 305

Query: 2208 RFLFTPLATTATTASTTTTTV----------------STTAAGTGEQRQ------SKLSP 2245
                 P  T  +TAS+  TTV                +TT + TG +        S+ S 
Sbjct: 306  ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365

Query: 2246 QMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTV 2305
                  + T    + S    A  +   A   +    +T   S    E  T     ++ T 
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 2306 SSHVPSEAQPTHAQSSKPQVAAQSQPQ---SNVQGQSPVRVQSP-SQTRIRPSTPSQLSP 2361
             S    E      + S+  +A+ S  +   ++ +G     V +  S+T+   +T S+ + 
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485

Query: 2362 GQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSS 2417
               + ++TTT   I     T+    ++G   +      S  T  S +     TVS+
Sbjct: 486  ASNTGLETTTVFTIGSDTTTA---STEGSETTAVSATGSEMTTVSTEGSENTTVST 538



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 76/412 (18%), Positives = 144/412 (34%), Gaps = 26/412 (6%)

Query: 2012 IPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQS 2071
            +  + G++  T ++    T T+ I+ + + +  T  +      P       V  +  + +
Sbjct: 7    VAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEIT 66

Query: 2072 TLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQ 2131
            T   A      +   G+     +       VSTA S   TVS T  + ++ SA  +    
Sbjct: 67   TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126

Query: 2132 SSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPG 2191
            +S +        +  +T    ++ T         T       +TT       +  TV   
Sbjct: 127  NSTTS------SETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 2192 PGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAA--GTGEQRQSKLSPQMQV 2249
              + +  +   + T          TT +TA + TTTVSTT +   T     S+ +    +
Sbjct: 181  GSETITPSTAGSET----------TTVSTAGSETTTVSTTGSETTTASTAHSETTAASTM 230

Query: 2250 HQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHV 2309
              + T      S    + A  +T   S +   +T        +  T      +TT +S  
Sbjct: 231  GSETTKVSTAGSETTVSTAGSETTAASTE-DSETNTAFTEDSKTTTASTTGFETTAASTT 289

Query: 2310 PSEAQPTHAQSSKPQVAAQSQPQS---NVQGQSPVRVQSPSQTRIRPST-PSQLSPGQQS 2365
             SE        S+  +A+   P++   +        V +     IR ST  S+ +    +
Sbjct: 290  GSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTT 349

Query: 2366 QVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSS 2417
              +TTT+  +  +  T     + G   +    + S  T +S +     TVS+
Sbjct: 350  GSETTTASIMGSETSTD---STTGSETTTASTEGSETTTASTEGSEATTVST 398



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 45/202 (22%), Positives = 73/202 (36%), Gaps = 15/202 (7%)

Query: 2216 TTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQP 2275
            T A  A + TTT STT + T        +  ++  +  T   A S +  P+    QT   
Sbjct: 6    TVAPAAGSNTTTASTTGSET-------TTILIKASETTTASTAGSETTTPSPTGSQTTIV 58

Query: 2276 SAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNV 2335
            S      T   S A  E  T     + TT +S   SE   + A S    V+      + V
Sbjct: 59   SISGSEIT-TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117

Query: 2336 QGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQP 2395
                       S+T    +T S+ +    +  +TTT   +  +  T+    S+    S  
Sbjct: 118  SAMG-------SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTT 170

Query: 2396 QVQSSTQTLSSGQTLNQVTVSS 2417
              + +T   +  +T+   T  S
Sbjct: 171  GSEMTTVFTAGSETITPSTAGS 192


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 192/978 (19%), Positives = 338/978 (34%), Gaps = 70/978 (7%)

Query: 1476 NERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDME 1535
            +E  ++ T+    +++  EG+   ++ T  S   + S   +  + +C E + +  V    
Sbjct: 371  SETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTV 430

Query: 1536 IETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVITEVTTMTSTV 1595
             ET+       S IT    S+         G           E+K        TT  S  
Sbjct: 431  FETTTAS-TEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNT 489

Query: 1596 ATESKTVIKV--------EKGDKQTVVS---------STENCAKSTVTTTTTTVTKLSTP 1638
              E+ TV  +         +G + T VS         STE    +TV+TT +  T +ST 
Sbjct: 490  GLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVST- 548

Query: 1639 STGGSVDIISVKEQSKTVVTTTVTDSLT--TTGGTLVTSMTVSKEYSTRDKVKLMKFSRP 1696
             TG      S +    T V+TT  ++ T  T G     + T   E +T      +  +  
Sbjct: 549  -TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTT------VSTADS 601

Query: 1697 KKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPY 1756
            + T + TA        T  S+ +     + +    + +G   E    +        +   
Sbjct: 602  ENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGS--ETTTVSTTDSETTMVSTT 659

Query: 1757 PSPRPTFGITWRYRLQTVKSLAGVSLMLR----LLWASLRWDDMAAKAPPGGGTTRTETS 1812
             S R T   T      TV +    + +          S+   +    +  G  TT T T 
Sbjct: 660  GSER-TITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTE 718

Query: 1813 ETEITTTEII--KRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPK 1870
             +EITT  I   +       G  +     +         T  ET T       ++     
Sbjct: 719  GSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIM 778

Query: 1871 RPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIAT 1930
              ET   +      T V+    ++  +  F E  E   A     +          T+ A+
Sbjct: 779  GSETTMASTIGSETTKVSTASSKMTTV--FTENSETTIASTTASETTTVSTAGSETIPAS 836

Query: 1931 STTSPTSSTTSTISPAQKVMVAPISGSVTT-----GTKMVLTTKVGSPATVTFQQNKNFH 1985
            +  S T++TTST     +   A   GS TT      ++    T +GS  T    +     
Sbjct: 837  TAGSETTTTTST--EGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS--- 891

Query: 1986 QTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGT 2045
            +T  T  +  ++ +   +  +       S+TG+   T ++    T T +   +   +  T
Sbjct: 892  ETTTTSTEGSETTTASTEGSEIT---TVSTTGSETTTASTEGSETTTASTEGSELTTVST 948

Query: 2046 TSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTA 2105
            T +  +    +     TV     + +T   A   T  +   G+  +  T  I G   +T 
Sbjct: 949  TGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGS--ETTTASIEGSETTTV 1006

Query: 2106 VSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGL 2165
             S  +  ++     + T+ TST   +++       +   V  T ++ T  T    G++  
Sbjct: 1007 SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT--TTSTEGSETT 1064

Query: 2166 TVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTT 2225
            TV   G   TT     +        G G      A  + T   ++     TTA+T  +  
Sbjct: 1065 TVSTTGSETTTASTADLETTTVSTSGSGTTTASTA-GSETTTVYITGSKTTTASTEGSEA 1123

Query: 2226 TTVSTTAA--GTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQT 2283
            TTVSTT++   T     S+++       + T      S    + A    A  ++    +T
Sbjct: 1124 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183

Query: 2284 QPQSPAQPEVQTQPEVQTQTTVSSHVPSE---AQPTHAQSSKPQVAAQSQ-------PQS 2333
               S A  E  T     ++TT +S   SE   A  T +++S P  A            ++
Sbjct: 1184 TTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSET 1243

Query: 2334 NVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQI-PSQGQPQ 2392
             +   + +   + S T    +T S  + G  +   T +S    +   T + I P    P 
Sbjct: 1244 TIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPM 1303

Query: 2393 SQPQVQSSTQTLSSGQTL 2410
            S  +   +  T SS  T+
Sbjct: 1304 SGTRTTGTRPTASSSVTM 1321



 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 216/1139 (18%), Positives = 389/1139 (34%), Gaps = 142/1139 (12%)

Query: 1197 ASRGQEPSKSKTKGNDFFI------DDSKLASAD-DIGTLICKNKKPL----IQEESDTI 1245
            ++ G EP+ + T G++  +      + +K+++A  ++ T+     + +    +  E+ T+
Sbjct: 287  STTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV 346

Query: 1246 VSSSKSALHSSVPKSTNDRDATPLSRAMDFEGKLGCDSESNSTLENSSDTVSIQDSSEED 1305
             ++      +S+  S    D+T  S       + G ++ + ST  + + TVS   S    
Sbjct: 347  STTGSETTTASIMGSETSTDSTTGSETTTASTE-GSETTTASTEGSEATTVSTTGSETTT 405

Query: 1306 MIVQNSNESISEQFRTREQDVEVLEPLKCELVSGESTGNCEDRLPVKGTEANGKKPSQQK 1365
            + + +S  + +    T   ++  +     E  +  + G+    + +  T  +    +  +
Sbjct: 406  VSITDSETTTT---CTEGSEMTAVSTTVFETTTASTEGS---EITIASTSDSETTTASTE 459

Query: 1366 KLEERPVNKCSDQIKLKNTTDKKNNENRESEKKGQRTSTFQINGKDNKPKIYLKGECLKE 1425
              E   V     + K   TT    +E   +   G  T+T    G D             E
Sbjct: 460  GSETTTVTTAGSETKTAYTT---GSETTTASNTGLETTTVFTIGSDTTT-------ASTE 509

Query: 1426 ISESRVVSGNVEPKVNNINKIIPENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKS 1485
             SE+  VS     ++  ++    EN   S T  E+          +     E  ++ T+ 
Sbjct: 510  GSETTAVSATGS-EMTTVSTEGSENTTVSTTGSETT--------TVSTTGLETTTTSTEG 560

Query: 1486 HLLSSSDAEG--NYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSEV-- 1541
              +++    G     DS E   +T  S +   TT  ++    N+     D E  ++    
Sbjct: 561  SEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG 620

Query: 1542 KKVTSSPITSEEESNLSNDFIDENGLPINKNENV---NGESKRKTVITEVTTMTSTVATE 1598
             + T++  TS E +  S +  +   +    +E        S+R    TE +  T+  AT 
Sbjct: 621  SETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATG 680

Query: 1599 SKTVIKVEKGDKQTV-VSSTENCAKSTV----TTTTTTVTKLSTPSTGGSVDIISVKEQS 1653
            S+T +  E     TV ++ +E    ST     TTT+T  ++++T S  GS    +  E S
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740

Query: 1654 KTVVTTTV---TDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRK 1710
            +T   +T    T S +TTG    T+ T S E +      +      + T + T      K
Sbjct: 741  ETTTASTEGSETTSASTTGSETTTASTTSSETT------MASIMGSETTMASTIGSETTK 794

Query: 1711 FVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYR 1770
              T SSK +     N +                                  T   T    
Sbjct: 795  VSTASSKMTTVFTENSET---------------------------------TIASTTASE 821

Query: 1771 LQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGG---TTRTETSETEITTTEIIKRRDV 1827
              TV +    ++      AS    +        G    T  TE SET   +TE  +    
Sbjct: 822  TTTVSTAGSETIP-----ASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTA 876

Query: 1828 GPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWV 1887
               G  +     +            ET T   +G   + +     ET   +      T  
Sbjct: 877  TTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTA 936

Query: 1888 AEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPA- 1946
            + E  EL  +           A+  E      +  +      T+T S   S T+T+S A 
Sbjct: 937  STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSE------TTTASTAGSETTTVSTAG 990

Query: 1947 QKVMVAPISGSVTT-----GTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGV 2001
             +   A I GS TT     G++    +  G+  T+T  +         T    G   + V
Sbjct: 991  SETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSE----TTTVTTAGSETTAV 1046

Query: 2002 VQVQQKVLGIIPSSTGTSQQTFTSFQPRTATV----TIRPNTSGSGGTTSNSQ------- 2050
                 +        + T+  + T  +  TA+     T   +TSGSG TT+++        
Sbjct: 1047 YTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV 1106

Query: 2051 VITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPN 2110
             ITG +     T      + +T+      T      G+    +   +      + + +  
Sbjct: 1107 YITGSKTTTAST---EGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163

Query: 2111 TVSSTPGQKSLTSAT---STSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTV 2167
            T SS  G ++ T++T    T+   ++ S+         + T A     T G   N   T 
Sbjct: 1164 TTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAS----TSGSETNTACTT 1219

Query: 2168 -----VIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTAS 2222
                      G  T    +I    T+      +    ++          T    TA + +
Sbjct: 1220 GSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTT 1279

Query: 2223 TTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQP 2281
             ++TT   T A     +    +P        T P A SSSV  A     TA  ++   P
Sbjct: 1280 VSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRPTA-SSSVTMAPGMDFTASAASHTVP 1337



 Score = 79.7 bits (195), Expect = 4e-14
 Identities = 182/1001 (18%), Positives = 340/1001 (33%), Gaps = 99/1001 (9%)

Query: 1481 SETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSE 1540
            SET + L+ +S+         ET  +T     +QTT  S S  E  + +         S 
Sbjct: 23   SETTTILIKASETTTASTAGSET--TTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSS 80

Query: 1541 VKKVTSSPITSEEESNLSNDFIDENGLPINKNEN-----VNGESKRKTVITEVTTMTSTV 1595
                T++   +  E+ +S    +   + I   E      +  E+   +  +  TT+TST 
Sbjct: 81   AGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTA 140

Query: 1596 ATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKT 1655
             +E+ TV  V  G + T    T   A S  T  +TT ++++T  T GS  I      S+T
Sbjct: 141  GSETTTVSTV--GSETT----TAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSET 194

Query: 1656 VVTTTV---TDSLTTTGGTLVTSMTVSKEYSTRDKV--KLMKFSRPKKTRSGTALPSYRK 1710
               +T    T +++TTG    T+ T   E +    +  +  K S      + +   S   
Sbjct: 195  TTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETT 254

Query: 1711 FVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPAL--------DIWPYPSPRPT 1762
              +    ++      D     A   G          ++P +         +     P  T
Sbjct: 255  AASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETT 314

Query: 1763 FGITWRYRLQTVKSLAGVSLMLRLL---------------WASLRWDDMAAKAPPGGGTT 1807
               T    + TV +    ++    +                AS+   + +  +  G  TT
Sbjct: 315  KVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETT 374

Query: 1808 --RTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSS 1865
               TE SET   +TE  +   V   G  +            V  T  ET T   +G   +
Sbjct: 375  TASTEGSETTTASTEGSEATTVSTTGSET----------TTVSITDSETTTTCTEGSEMT 424

Query: 1866 ALRPKRPETPKQT--GPVII--------ETWVAEEELELWEIRAFAERVEKEKAQAVEQQ 1915
            A+     ET   +  G  I          T  + E  E   +       +       E  
Sbjct: 425  AVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETT 484

Query: 1916 AKKRLEQQKPTVIATSTTSPTSS-----TTSTISPAQKVMVAPISGS-----VTTGTKMV 1965
                   +  TV    + + T+S     TT+  +   ++      GS      TTG++  
Sbjct: 485  TASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETT 544

Query: 1966 LTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTS 2025
              +  G   T T  +         T  +    ++       +  G   +ST  S+ T  S
Sbjct: 545  TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST-------EGSGTTAASTAGSETTTVS 597

Query: 2026 FQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQ 2085
                  T     ++  +  +T+ S+  T        T   T   ++T          MV 
Sbjct: 598  TADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS 657

Query: 2086 PGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLT---SATSTSNIQSSASQPPRPQQ 2142
                ++ +T     +  + + +   T  ST G  + T   + + T+ + ++ S+      
Sbjct: 658  TTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTST 717

Query: 2143 GQVKLTMAQLT---QLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQA 2199
               ++T A +T     T    G++  T   +G  +TT       +  T      +  M +
Sbjct: 718  EGSEITTASITGSETTTASTEGSETTTASTEG-SETTSASTTGSETTTASTTSSETTMAS 776

Query: 2200 AMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQ 2259
             M + T          T  +TAS+  TTV T      E  ++ ++      +  T+  A 
Sbjct: 777  IMGSETTMASTIGSETTKVSTASSKMTTVFT------ENSETTIA-STTASETTTVSTAG 829

Query: 2260 SSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQ 2319
            S ++  + A  +T   ++    +T   S    E  T     ++TT ++ + SE      +
Sbjct: 830  SETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTE 889

Query: 2320 SSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQP 2379
             S+    +    ++         + + S T    +T S  + G ++   +T    +    
Sbjct: 890  GSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS--TEGSETTTASTEGSELTTVS 947

Query: 2380 HT---SLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSS 2417
             T   ++ + ++G   +      S  T +S       TVS+
Sbjct: 948  TTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVST 988



 Score = 73.2 bits (178), Expect = 4e-12
 Identities = 189/933 (20%), Positives = 316/933 (33%), Gaps = 86/933 (9%)

Query: 1506 STKESDSTQTTTPSASCPESNSVNQVEDMEIETS--EVKKVTSSPITSEEESNLSNDFID 1563
            +TK S +   TT S +  E+ + +  ED E  T+  E  K T++  T  E +  S     
Sbjct: 234  TTKVSTAGSETTVSTAGSETTAAS-TEDSETNTAFTEDSKTTTASTTGFETTAAST---- 288

Query: 1564 ENGLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENCAKS 1623
              G        +  E+   + I   TT  ST ++E  TV        +T+ +ST     +
Sbjct: 289  -TGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAA---GSETIRASTVGSETT 344

Query: 1624 TVTTT---TTTVT----KLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTT--TGGTLVT 1674
            TV+TT   TTT +    + ST ST GS    +  E S+T   +T     TT  T G+  T
Sbjct: 345  TVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETT 404

Query: 1675 SMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARK 1734
            +++++   +T    +  + +    T   T   S     T+ S+ +I    + +    + +
Sbjct: 405  TVSITDSETTTTCTEGSEMTAVSTTVFETTTAS-----TEGSEITIASTSDSETTTASTE 459

Query: 1735 GG-IREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRW 1793
            G     V       K A       +     G+       TV ++   +       AS   
Sbjct: 460  GSETTTVTTAGSETKTAYTTGSETTTASNTGL----ETTTVFTIGSDTTT-----ASTEG 510

Query: 1794 DDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKE 1853
             +  A +  G   T   T  +E TT                            V  T  E
Sbjct: 511  SETTAVSATGSEMTTVSTEGSENTT----------------------------VSTTGSE 542

Query: 1854 TPTPQRKGLRSSALRPKRPE-TPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAV 1912
            T T    GL ++    +  E T   T      T   E         A +E      A + 
Sbjct: 543  TTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADS- 601

Query: 1913 EQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGS 1972
            E       + +  +   T + + T+STTS+ +       +  +   TT ++  + +  GS
Sbjct: 602  ENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGS 661

Query: 1973 PATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLG--IIPSSTGTSQQTFTSFQPRT 2030
              T+T  +        AT  +   S  G       + G      ST  S+ T TS +   
Sbjct: 662  ERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSE 721

Query: 2031 ATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQ 2090
             T      +  +  +T  S+  T        T   T   ++T          M      +
Sbjct: 722  ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSE 781

Query: 2091 QVMTQIIRGQ--PVSTAVSAPNTVSSTPGQKSLTSAT-STSNIQSSASQPPRPQQGQVKL 2147
              M   I  +   VSTA S   TV +   + ++ S T S +   S+A     P       
Sbjct: 782  TTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAS----- 836

Query: 2148 TMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNG-TV 2206
            T    T  T    G++  T   +G   TT   +      T     G +   A+     T 
Sbjct: 837  TAGSETTTTTSTEGSETTTASTEGSETTTASTE--SSETTTATTIGSETTTASTEGSETT 894

Query: 2207 QRFLFTPLATTATTASTTTTTVSTTAA--GTGEQRQSKLSPQMQVHQDKTLPPAQSSSVG 2264
                     TTA+T  +  TTVSTT +   T     S+ +       + T      S   
Sbjct: 895  TTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETI 954

Query: 2265 PAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQ 2324
               A+            +T   S A  E  T     ++TT +S   SE     +  S+  
Sbjct: 955  TVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETT 1014

Query: 2325 VAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQ 2384
              + +  ++ +           S+T    +  S+ +    +  +TTT+     +  T   
Sbjct: 1015 TVSTTGTETTITS------TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST 1068

Query: 2385 IPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSS 2417
              S+    S   ++++T + S   T    T  S
Sbjct: 1069 TGSETTTASTADLETTTVSTSGSGTTTASTAGS 1101



 Score = 62.4 bits (150), Expect = 6e-09
 Identities = 212/1135 (18%), Positives = 374/1135 (32%), Gaps = 168/1135 (14%)

Query: 1338 SGESTGNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKN----TTDKKNNENR 1393
            +  +TG+    + +K +E      +  +     P    +  + +      TT    +EN 
Sbjct: 17   TASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENT 76

Query: 1394 ESEKKGQRTSTFQINGKDNKPKIYLKGECLKEISESRVVSGNVEPKVNNINKIIPENDIK 1453
                 G  T+T  + G +    +   G     +S    ++G     V+ +     E    
Sbjct: 77   TVSSAGSGTTTASMAGSETT--VSTAGSETTTVS----ITGTETTMVSAMGS---ETTTN 127

Query: 1454 SLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDST 1513
            S T  E+ +             +   S  T    + S        DS  T  ST  S+ T
Sbjct: 128  STTSSETTVT------------STAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMT 175

Query: 1514 -------QTTTPSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSNDFIDENG 1566
                   +T TPS +  E+ +V+         S     T++  T+  E+  ++      G
Sbjct: 176  TVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTM----G 231

Query: 1567 LPINKNENVNGESKRKTVITEVTTM------TSTVATE-SKTVIKVEKGDKQTVVSST-- 1617
                K      E+   T  +E T        T+T  TE SKT      G + T  S+T  
Sbjct: 232  SETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGS 291

Query: 1618 ENCAKSTVTTTTTTV-------TKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGG 1670
            E    ST+ + TT         TK+ST S+  +    +  E  +     + T +++TTG 
Sbjct: 292  EPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGS 351

Query: 1671 TLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKK 1730
               T+  +  E ST              T S T   S     T+ S+ +       +   
Sbjct: 352  ETTTASIMGSETST-----------DSTTGSETTTAS-----TEGSETTTASTEGSEATT 395

Query: 1731 LARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTV----KSLAGVSLMLRL 1786
            ++  G                      S   T  IT      T     +  A  + +   
Sbjct: 396  VSTTG----------------------SETTTVSITDSETTTTCTEGSEMTAVSTTVFET 433

Query: 1787 LWASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIG 1846
              AS    ++   +     TT   T  +E TT           Y   SE           
Sbjct: 434  TTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE--------TTT 485

Query: 1847 VPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEK 1906
               T  ET T    G  ++    +  ET   +      T V+ E  E   +         
Sbjct: 486  ASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTT 545

Query: 1907 EKAQAVEQQAKKRLEQQKPTVIATSTTSPTSST-------TSTISPAQKVMVAPISGSVT 1959
                 +E         +  TV  T   + T ST        ST       +    S + T
Sbjct: 546  VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 1960 TGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTS 2019
              T    TT   +  + T   +    +T  T   +G   + V     +   +   ST  S
Sbjct: 606  ASTADSETTSASTTGSETTTASTTSSET-TTASTEGSETTTVSTTDSETTMV---STTGS 661

Query: 2020 QQTFTSFQ-PRTATVT-----IRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTL 2073
            ++T TS +   T TV+        +T GSG TT +   ITG +     T        ST 
Sbjct: 662  ERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS---ITGSETTKVSTTGSETTTTSTE 718

Query: 2074 GKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVS--APNTVSSTPGQKSLTSATSTSNIQ 2131
            G                ++ T  I G   +TA +  +  T +ST G ++ +++T+ S   
Sbjct: 719  G---------------SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETT 763

Query: 2132 SSASQPPRPQQGQV---KLTMAQL--TQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGV 2186
            ++++         +   + TMA    ++ T+    +  +T V     +TT       +  
Sbjct: 764  TASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETT 823

Query: 2187 TVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQ 2246
            TV     +                 T  A+TA + +TTTT+   +   T     S+ +  
Sbjct: 824  TVSTAGSE-----------------TIPASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 2247 MQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVS 2306
                 + T      S    A  +      ++    +T   S    E+ T     ++TT +
Sbjct: 867  STESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTA 926

Query: 2307 SHVPSEAQPTHAQSSKPQVAAQSQPQS---NVQGQSPVRVQS-PSQTRIRPSTPSQLSPG 2362
            S   SE      + S+    + +  ++   + +G     V +  S+T    +  S+ +  
Sbjct: 927  STEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTV 986

Query: 2363 QQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSS 2417
              +  +TTT+    I+   +  + S G   +      +  T++S +     TV++
Sbjct: 987  STAGSETTTAS---IEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTT 1038



 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 212/1128 (18%), Positives = 380/1128 (33%), Gaps = 160/1128 (14%)

Query: 973  KGSDAAKGADQNEMDISKITEKKDQDVKELLDSDSDKPCKE-EPMEVDDDMKTESHVNCQ 1031
            +GS+    + +     +  T   +     + DS++   C E   M        E+     
Sbjct: 379  EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438

Query: 1032 ESSQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIKQFTLEEKQRLEKIKLEGG-IKG 1090
            E S++ + + S+      S +    ++      E +    T  E        LE   +  
Sbjct: 439  EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFT 498

Query: 1091 IGKTSTNSSKNLSESPVITKAKEGCQSDSMRQEQSPNANNDQPEDLIQGCSESDSSVLRM 1150
            IG  +T +S   SE+  ++    G +  ++  E S N             S + S    +
Sbjct: 499  IGSDTTTASTEGSETTAVSAT--GSEMTTVSTEGSENTT----------VSTTGSETTTV 546

Query: 1151 SDPSHTTNKLYPKDRVLDDVSIRSPETKCPKQNSIENDIEEKVSDLASRGQEPSKSKTKG 1210
            S     T     +   +  VS    ET     +S E       S   S     S + ++ 
Sbjct: 547  STTGLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTAASTAGSETTTVSTADSEN 603

Query: 1211 NDFFIDDSKLASADDIGTLICKNKKPLIQEESDTIVSSSKSALHSSVPKSTNDRDATPLS 1270
                  DS+  SA   G+             S+T  +S++ +  ++V  ST D + T +S
Sbjct: 604  TTASTADSETTSASTTGS----ETTTASTTSSETTTASTEGSETTTV--STTDSETTMVS 657

Query: 1271 RAMDFEGKLGCDSESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLE 1330
                        SE   T    S+T ++  +  E  +        +E   T    +   E
Sbjct: 658  TT---------GSERTITSTEGSETTTVSATGSETTVS-------TEGSGTTTVSITGSE 701

Query: 1331 PLKCELVSGESTGNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNN 1390
              K      E+T    +   +      G + +             S +     T   + +
Sbjct: 702  TTKVSTTGSETTTTSTEGSEITTASITGSETTT-----------ASTEGSETTTASTEGS 750

Query: 1391 ENRESEKKGQRTSTFQINGKDNKPKIYLKGECLKEI---SESRVVSGNVEPKVNNINKII 1447
            E   +   G  T+T      +      +  E        SE+  VS     K+  +    
Sbjct: 751  ETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS-TASSKMTTVFTEN 809

Query: 1448 PENDIKSLTVKESAIRPFINGDVI-------------MEDFNERNSSETKSHLLSSSDAE 1494
             E  I S T  E+        + I               + +E  ++ T+    +++  E
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTE 869

Query: 1495 GNYRDSLETLPS---TKESDSTQTTTPSASCPESNSVNQVEDMEIETSEV--KKVTSSPI 1549
             +   +  T+ S   T  ++ ++TTT S    E+ + +  E  EI T      + T++  
Sbjct: 870  SSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAS-TEGSEITTVSTTGSETTTAST 928

Query: 1550 TSEEESNLSNDFIDENGLPINKNEN--VNGESKRKTVITEV---TTMTSTVATESKTVIK 1604
               E +  S +  +   +    +E   V+ E    T +T +   TT  ST  +E+ TV  
Sbjct: 929  EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVST 988

Query: 1605 VE--------KGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTV 1656
                      +G + T VSST +   +TV+TT T  T  ST   G     ++      T 
Sbjct: 989  AGSETTTASIEGSETTTVSSTGS-ETTTVSTTGTETTITST--EGSETTTVTTAGSETTA 1045

Query: 1657 VTTTVTDSLTT-TGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKS 1715
            V TT +++ TT T G+  T+++ +   +T      ++ +    + SGT   S     T  
Sbjct: 1046 VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAS-----TAG 1100

Query: 1716 SKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVK 1775
            S+ +   +        + +G           A          +   T G        TV 
Sbjct: 1101 SETTTVYITGSKTTTASTEGS---------EATTVSTTSSETTTASTTGSEMTTVFTTVS 1151

Query: 1776 SLAGVSLM-LRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRS 1834
                VS +      +S    +    +  G  TT   T+ +E TT               S
Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGS 1211

Query: 1835 EYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVI-IETWVAEEELE 1893
            E       C  G      ET TP   G  ++            T  +I  ET +A     
Sbjct: 1212 E---TNTACTTG-----SETSTPSSAGSETN------------TAFIIGSETTIA----- 1246

Query: 1894 LWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATST-----TSPTSSTTSTISPAQK 1948
                             ++E  A      +  TV  T++     ++  SSTT  ++ A  
Sbjct: 1247 --------------STASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATD 1292

Query: 1949 VMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQG--QSNSGV----- 2001
            V + PI+ +  +GT+   T    S ++VT     +F  + A+    G   + SG+     
Sbjct: 1293 VSIQPITNTPMSGTRTTGTRPTAS-SSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTM 1351

Query: 2002 -VQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSN 2048
                     G+  ++  T + T ++FQ  T  V++  NT     T +N
Sbjct: 1352 GASSTTSAHGVRTTTGSTREPTSSTFQ-ETGPVSMGTNTVSMSHTPTN 1398



 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 101/536 (18%), Positives = 184/536 (34%), Gaps = 54/536 (10%)

Query: 1929 ATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTF 1988
            A  + + T+STT + +    +  +  + + T G++    +  GS  T+          T 
Sbjct: 10   AAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS 69

Query: 1989 ATWVKQ---GQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGT 2045
                +      + SG             S+ G+   T +     T  V+   + + +  T
Sbjct: 70   TAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNST 129

Query: 2046 TSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPG--------APQQVMTQII 2097
            TS+   +T        TV     + +T   A   T      G        A  + +T   
Sbjct: 130  TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPST 189

Query: 2098 RGQ---PVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQ 2154
             G     VSTA S   TVS+T  +   T+  ST++ +++A+     +  +V    ++ T 
Sbjct: 190  AGSETTTVSTAGSETTTVSTTGSE---TTTASTAHSETTAASTMGSETTKVSTAGSETTV 246

Query: 2155 LTQGH-------GGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQ 2207
             T G          ++  T   +    TT              G  +  M + M + T  
Sbjct: 247  STAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTG-SEPTMASTMGSETTM 305

Query: 2208 RFLFTPLATTATTASTTTTTV----------------STTAAGTGEQRQ------SKLSP 2245
                 P  T  +TAS+  TTV                +TT + TG +        S+ S 
Sbjct: 306  ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365

Query: 2246 QMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTV 2305
                  + T    + S    A  +   A   +    +T   S    E  T     ++ T 
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 2306 SSHVPSEAQPTHAQSSKPQVAAQSQPQ---SNVQGQSPVRVQSP-SQTRIRPSTPSQLSP 2361
             S    E      + S+  +A+ S  +   ++ +G     V +  S+T+   +T S+ + 
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485

Query: 2362 GQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSS 2417
               + ++TTT   I     T+    ++G   +      S  T  S +     TVS+
Sbjct: 486  ASNTGLETTTVFTIGSDTTTA---STEGSETTAVSATGSEMTTVSTEGSENTTVST 538



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 76/412 (18%), Positives = 144/412 (34%), Gaps = 26/412 (6%)

Query: 2012 IPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQS 2071
            +  + G++  T ++    T T+ I+ + + +  T  +      P       V  +  + +
Sbjct: 7    VAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEIT 66

Query: 2072 TLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQ 2131
            T   A      +   G+     +       VSTA S   TVS T  + ++ SA  +    
Sbjct: 67   TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126

Query: 2132 SSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPG 2191
            +S +        +  +T    ++ T         T       +TT       +  TV   
Sbjct: 127  NSTTS------SETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 2192 PGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAA--GTGEQRQSKLSPQMQV 2249
              + +  +   + T          TT +TA + TTTVSTT +   T     S+ +    +
Sbjct: 181  GSETITPSTAGSET----------TTVSTAGSETTTVSTTGSETTTASTAHSETTAASTM 230

Query: 2250 HQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHV 2309
              + T      S    + A  +T   S +   +T        +  T      +TT +S  
Sbjct: 231  GSETTKVSTAGSETTVSTAGSETTAASTE-DSETNTAFTEDSKTTTASTTGFETTAASTT 289

Query: 2310 PSEAQPTHAQSSKPQVAAQSQPQS---NVQGQSPVRVQSPSQTRIRPST-PSQLSPGQQS 2365
             SE        S+  +A+   P++   +        V +     IR ST  S+ +    +
Sbjct: 290  GSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTT 349

Query: 2366 QVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSS 2417
              +TTT+  +  +  T     + G   +    + S  T +S +     TVS+
Sbjct: 350  GSETTTASIMGSETSTD---STTGSETTTASTEGSETTTASTEGSEATTVST 398



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 45/202 (22%), Positives = 73/202 (36%), Gaps = 15/202 (7%)

Query: 2216 TTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQP 2275
            T A  A + TTT STT + T        +  ++  +  T   A S +  P+    QT   
Sbjct: 6    TVAPAAGSNTTTASTTGSET-------TTILIKASETTTASTAGSETTTPSPTGSQTTIV 58

Query: 2276 SAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNV 2335
            S      T   S A  E  T     + TT +S   SE   + A S    V+      + V
Sbjct: 59   SISGSEIT-TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117

Query: 2336 QGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQP 2395
                       S+T    +T S+ +    +  +TTT   +  +  T+    S+    S  
Sbjct: 118  SAMG-------SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTT 170

Query: 2396 QVQSSTQTLSSGQTLNQVTVSS 2417
              + +T   +  +T+   T  S
Sbjct: 171  GSEMTTVFTAGSETITPSTAGS 192


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 91.7 bits (226), Expect = 1e-17
 Identities = 128/509 (25%), Positives = 180/509 (35%), Gaps = 82/509 (16%)

Query: 1925 PTVIATSTTSPTS---STTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQN 1981
            PT   T T +PT+   +TT+T++P              TGT+   TT + +  TVT    
Sbjct: 3818 PTPTPTGTQTPTTTPITTTTTVTPT----------PTPTGTQTPTTTPITTTTTVTPTPT 3867

Query: 1982 KNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSG 2041
                QT  T      +             + P+ T T  QT T+  P T T T+ P  + 
Sbjct: 3868 PTGTQTPTTTPITTTTT------------VTPTPTPTGTQTPTT-TPITTTTTVTPTPTP 3914

Query: 2042 SGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQP 2101
            +G  T  +  IT       +T   TP    T     I T   V P  P    TQ     P
Sbjct: 3915 TGTQTPTTTPIT---TTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQ----TP 3966

Query: 2102 VSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQP-PRPQQGQVKLTMAQLTQLTQGHG 2160
             +T ++   TV+ TP      + T+T    ++   P P P   Q   T    T  T    
Sbjct: 3967 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT---- 4022

Query: 2161 GNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATT 2220
                +T      G  T     I    TV P P         P GT          T  TT
Sbjct: 4023 ----VTPTPTPTGTQTPTTTPITTTTTVTPTP--------TPTGT---------QTPTTT 4061

Query: 2221 ASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQ 2280
              TTTTTV+ T   TG Q  +            T P   +++V P      T  P+  P 
Sbjct: 4062 PITTTTTVTPTPTPTGTQTPT------------TTPITTTTTVTPTPTPTGTQTPTTTPI 4109

Query: 2281 PQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSP 2340
              T   +P      TQ    T  T ++ V     PT  Q+  P     +   +     +P
Sbjct: 4110 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP 4167

Query: 2341 VRVQSPSQTRIRPS---TPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQ----- 2392
               Q+P+ T I  +   TP+    G Q+   T TS     +  TS   P    PQ     
Sbjct: 4168 TGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRST 4227

Query: 2393 SQPQVQSSTQTLSSGQTLNQVTVSSPSRP 2421
            S P  +S+T   +    +   + + PS P
Sbjct: 4228 SSPLTESTTLLSTLPPAIEMTSTAPPSTP 4256



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 128/503 (25%), Positives = 181/503 (35%), Gaps = 77/503 (15%)

Query: 1924 KPTVIATSTT-SPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNK 1982
            +PT + T+TT +PT  TT+ I+    V   P      TGT+   TT + +  TVT     
Sbjct: 1881 QPTTMTTTTTENPTPPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTVTPTPTP 1936

Query: 1983 NFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGS 2042
               QT  T      +             + P+ T T  QT T+  P T T T+ P  + +
Sbjct: 1937 TGTQTPTTTPITTTTT------------VTPTPTPTGTQTPTT-TPITTTTTVTPTPTPT 1983

Query: 2043 GGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPV 2102
            G  T  +  IT       +T   TP    T     I T   V P  P    TQ     P 
Sbjct: 1984 GTQTPTTTPIT---TTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQ----TPT 2035

Query: 2103 STAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQP-PRPQQGQVKLTMAQLTQLTQGHGG 2161
            +T ++   TV+ TP      + T+T    ++   P P P   Q   T    T  T     
Sbjct: 2036 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT----- 2090

Query: 2162 NQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTA 2221
               +T      G  T     I    TV P P         P GT          T  TT 
Sbjct: 2091 ---VTPTPTPTGTQTPTTTPITTTTTVTPTP--------TPTGT---------QTPTTTP 2130

Query: 2222 STTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQP 2281
             TTTTTV+ T   TG Q  +            T P   +++V P      T  P+  P  
Sbjct: 2131 ITTTTTVTPTPTPTGTQTPT------------TTPITTTTTVTPTPTPTGTQTPTTTPIT 2178

Query: 2282 QTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPV 2341
             T   +P      TQ    T  T ++ V     PT  Q+  P     +   +     +P 
Sbjct: 2179 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPT 2236

Query: 2342 RVQSPSQTRIRPS---TPSQLSPGQQSQVQ---TTTSQPIPIQPHTSLQIPSQGQPQSQP 2395
              Q+P+ T I  +   TP+    G Q+      TTT+   P    T  Q P+     + P
Sbjct: 2237 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTP 2291

Query: 2396 QVQSSTQTLSSGQTLNQVTVSSP 2418
               ++T T +   T  Q   ++P
Sbjct: 2292 ITTTTTVTPTPTPTGTQTPTTTP 2314



 Score = 89.0 bits (219), Expect = 6e-17
 Identities = 128/516 (24%), Positives = 184/516 (35%), Gaps = 86/516 (16%)

Query: 1925 PTVIATSTTSPTSS---TTSTISPA------QKVMVAPISGSVT-------TGTKMVLTT 1968
            PT   T T +PT++   TT+T++P       Q     PI+ + T       TGT+   TT
Sbjct: 2047 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2106

Query: 1969 KVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQP 2028
             + +  TVT        QT  T      +             + P+ T T  QT T+  P
Sbjct: 2107 PITTTTTVTPTPTPTGTQTPTTTPITTTTT------------VTPTPTPTGTQTPTT-TP 2153

Query: 2029 RTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGA 2088
             T T T+ P  + +G  T  +  IT       +T   TP    T     I T   V P  
Sbjct: 2154 ITTTTTVTPTPTPTGTQTPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTP-T 2209

Query: 2089 PQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLT 2148
            P    TQ     P +T ++   TV+ TP      + T+T    ++   P     G    T
Sbjct: 2210 PTPTGTQT----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2265

Query: 2149 MAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQR 2208
               +T  T        +T      G  T     I    TV P P         P GT   
Sbjct: 2266 TTPITTTTT-------VTPTPTPTGTQTPTTTPITTTTTVTPTP--------TPTGT--- 2307

Query: 2209 FLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEA 2268
                   T  TT  TTTTTV+ T   TG Q  +            T P   +++V P   
Sbjct: 2308 ------QTPTTTPITTTTTVTPTPTPTGTQTPT------------TTPITTTTTVTPTPT 2349

Query: 2269 QPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQ 2328
               T  P+  P   T   +P      TQ    T  T ++ V     PT  Q+  P     
Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPI 2407

Query: 2329 SQPQSNVQGQSPVRVQSPSQTRIRPS---TPSQLSPGQQSQVQ---TTTSQPIPIQPHTS 2382
            +   +     +P   Q+P+ T I  +   TP+    G Q+      TTT+   P    T 
Sbjct: 2408 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2467

Query: 2383 LQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSP 2418
             Q P+     + P   ++T T +   T  Q   ++P
Sbjct: 2468 TQTPT-----TTPITTTTTVTPTPTPTGTQTPTTTP 2498



 Score = 89.0 bits (219), Expect = 6e-17
 Identities = 128/516 (24%), Positives = 184/516 (35%), Gaps = 86/516 (16%)

Query: 1925 PTVIATSTTSPTSS---TTSTISPA------QKVMVAPISGSVT-------TGTKMVLTT 1968
            PT   T T +PT++   TT+T++P       Q     PI+ + T       TGT+   TT
Sbjct: 2231 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2290

Query: 1969 KVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQP 2028
             + +  TVT        QT  T      +             + P+ T T  QT T+  P
Sbjct: 2291 PITTTTTVTPTPTPTGTQTPTTTPITTTTT------------VTPTPTPTGTQTPTT-TP 2337

Query: 2029 RTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGA 2088
             T T T+ P  + +G  T  +  IT       +T   TP    T     I T   V P  
Sbjct: 2338 ITTTTTVTPTPTPTGTQTPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTP-T 2393

Query: 2089 PQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLT 2148
            P    TQ     P +T ++   TV+ TP      + T+T    ++   P     G    T
Sbjct: 2394 PTPTGTQT----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2449

Query: 2149 MAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQR 2208
               +T  T        +T      G  T     I    TV P P         P GT   
Sbjct: 2450 TTPITTTTT-------VTPTPTPTGTQTPTTTPITTTTTVTPTP--------TPTGT--- 2491

Query: 2209 FLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEA 2268
                   T  TT  TTTTTV+ T   TG Q  +            T P   +++V P   
Sbjct: 2492 ------QTPTTTPITTTTTVTPTPTPTGTQTPT------------TTPITTTTTVTPTPT 2533

Query: 2269 QPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQ 2328
               T  P+  P   T   +P      TQ    T  T ++ V     PT  Q+  P     
Sbjct: 2534 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPI 2591

Query: 2329 SQPQSNVQGQSPVRVQSPSQTRIRPS---TPSQLSPGQQSQVQ---TTTSQPIPIQPHTS 2382
            +   +     +P   Q+P+ T I  +   TP+    G Q+      TTT+   P    T 
Sbjct: 2592 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2651

Query: 2383 LQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSP 2418
             Q P+     + P   ++T T +   T  Q   ++P
Sbjct: 2652 TQTPT-----TTPITTTTTVTPTPTPTGTQTPTTTP 2682



 Score = 89.0 bits (219), Expect = 6e-17
 Identities = 128/516 (24%), Positives = 184/516 (35%), Gaps = 86/516 (16%)

Query: 1925 PTVIATSTTSPTSS---TTSTISPA------QKVMVAPISGSVT-------TGTKMVLTT 1968
            PT   T T +PT++   TT+T++P       Q     PI+ + T       TGT+   TT
Sbjct: 2415 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2474

Query: 1969 KVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQP 2028
             + +  TVT        QT  T      +             + P+ T T  QT T+  P
Sbjct: 2475 PITTTTTVTPTPTPTGTQTPTTTPITTTTT------------VTPTPTPTGTQTPTT-TP 2521

Query: 2029 RTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGA 2088
             T T T+ P  + +G  T  +  IT       +T   TP    T     I T   V P  
Sbjct: 2522 ITTTTTVTPTPTPTGTQTPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTP-T 2577

Query: 2089 PQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLT 2148
            P    TQ     P +T ++   TV+ TP      + T+T    ++   P     G    T
Sbjct: 2578 PTPTGTQT----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2633

Query: 2149 MAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQR 2208
               +T  T        +T      G  T     I    TV P P         P GT   
Sbjct: 2634 TTPITTTTT-------VTPTPTPTGTQTPTTTPITTTTTVTPTP--------TPTGT--- 2675

Query: 2209 FLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEA 2268
                   T  TT  TTTTTV+ T   TG Q  +            T P   +++V P   
Sbjct: 2676 ------QTPTTTPITTTTTVTPTPTPTGTQTPT------------TTPITTTTTVTPTPT 2717

Query: 2269 QPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQ 2328
               T  P+  P   T   +P      TQ    T  T ++ V     PT  Q+  P     
Sbjct: 2718 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPI 2775

Query: 2329 SQPQSNVQGQSPVRVQSPSQTRIRPS---TPSQLSPGQQSQVQ---TTTSQPIPIQPHTS 2382
            +   +     +P   Q+P+ T I  +   TP+    G Q+      TTT+   P    T 
Sbjct: 2776 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2835

Query: 2383 LQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSP 2418
             Q P+     + P   ++T T +   T  Q   ++P
Sbjct: 2836 TQTPT-----TTPITTTTTVTPTPTPTGTQTPTTTP 2866



 Score = 89.0 bits (219), Expect = 6e-17
 Identities = 128/516 (24%), Positives = 184/516 (35%), Gaps = 86/516 (16%)

Query: 1925 PTVIATSTTSPTSS---TTSTISPA------QKVMVAPISGSVT-------TGTKMVLTT 1968
            PT   T T +PT++   TT+T++P       Q     PI+ + T       TGT+   TT
Sbjct: 2599 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2658

Query: 1969 KVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQP 2028
             + +  TVT        QT  T      +             + P+ T T  QT T+  P
Sbjct: 2659 PITTTTTVTPTPTPTGTQTPTTTPITTTTT------------VTPTPTPTGTQTPTT-TP 2705

Query: 2029 RTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGA 2088
             T T T+ P  + +G  T  +  IT       +T   TP    T     I T   V P  
Sbjct: 2706 ITTTTTVTPTPTPTGTQTPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTP-T 2761

Query: 2089 PQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLT 2148
            P    TQ     P +T ++   TV+ TP      + T+T    ++   P     G    T
Sbjct: 2762 PTPTGTQT----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2817

Query: 2149 MAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQR 2208
               +T  T        +T      G  T     I    TV P P         P GT   
Sbjct: 2818 TTPITTTTT-------VTPTPTPTGTQTPTTTPITTTTTVTPTP--------TPTGT--- 2859

Query: 2209 FLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEA 2268
                   T  TT  TTTTTV+ T   TG Q  +            T P   +++V P   
Sbjct: 2860 ------QTPTTTPITTTTTVTPTPTPTGTQTPT------------TTPITTTTTVTPTPT 2901

Query: 2269 QPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQ 2328
               T  P+  P   T   +P      TQ    T  T ++ V     PT  Q+  P     
Sbjct: 2902 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPI 2959

Query: 2329 SQPQSNVQGQSPVRVQSPSQTRIRPS---TPSQLSPGQQSQVQ---TTTSQPIPIQPHTS 2382
            +   +     +P   Q+P+ T I  +   TP+    G Q+      TTT+   P    T 
Sbjct: 2960 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3019

Query: 2383 LQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSP 2418
             Q P+     + P   ++T T +   T  Q   ++P
Sbjct: 3020 TQTPT-----TTPITTTTTVTPTPTPTGTQTPTTTP 3050



 Score = 89.0 bits (219), Expect = 6e-17
 Identities = 128/516 (24%), Positives = 184/516 (35%), Gaps = 86/516 (16%)

Query: 1925 PTVIATSTTSPTSS---TTSTISPA------QKVMVAPISGSVT-------TGTKMVLTT 1968
            PT   T T +PT++   TT+T++P       Q     PI+ + T       TGT+   TT
Sbjct: 2783 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2842

Query: 1969 KVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQP 2028
             + +  TVT        QT  T      +             + P+ T T  QT T+  P
Sbjct: 2843 PITTTTTVTPTPTPTGTQTPTTTPITTTTT------------VTPTPTPTGTQTPTT-TP 2889

Query: 2029 RTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGA 2088
             T T T+ P  + +G  T  +  IT       +T   TP    T     I T   V P  
Sbjct: 2890 ITTTTTVTPTPTPTGTQTPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTP-T 2945

Query: 2089 PQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLT 2148
            P    TQ     P +T ++   TV+ TP      + T+T    ++   P     G    T
Sbjct: 2946 PTPTGTQT----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3001

Query: 2149 MAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQR 2208
               +T  T        +T      G  T     I    TV P P         P GT   
Sbjct: 3002 TTPITTTTT-------VTPTPTPTGTQTPTTTPITTTTTVTPTP--------TPTGT--- 3043

Query: 2209 FLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEA 2268
                   T  TT  TTTTTV+ T   TG Q  +            T P   +++V P   
Sbjct: 3044 ------QTPTTTPITTTTTVTPTPTPTGTQTPT------------TTPITTTTTVTPTPT 3085

Query: 2269 QPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQ 2328
               T  P+  P   T   +P      TQ    T  T ++ V     PT  Q+  P     
Sbjct: 3086 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPI 3143

Query: 2329 SQPQSNVQGQSPVRVQSPSQTRIRPS---TPSQLSPGQQSQVQ---TTTSQPIPIQPHTS 2382
            +   +     +P   Q+P+ T I  +   TP+    G Q+      TTT+   P    T 
Sbjct: 3144 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3203

Query: 2383 LQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSP 2418
             Q P+     + P   ++T T +   T  Q   ++P
Sbjct: 3204 TQTPT-----TTPITTTTTVTPTPTPTGTQTPTTTP 3234



 Score = 89.0 bits (219), Expect = 6e-17
 Identities = 128/516 (24%), Positives = 184/516 (35%), Gaps = 86/516 (16%)

Query: 1925 PTVIATSTTSPTSS---TTSTISPA------QKVMVAPISGSVT-------TGTKMVLTT 1968
            PT   T T +PT++   TT+T++P       Q     PI+ + T       TGT+   TT
Sbjct: 2967 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3026

Query: 1969 KVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQP 2028
             + +  TVT        QT  T      +             + P+ T T  QT T+  P
Sbjct: 3027 PITTTTTVTPTPTPTGTQTPTTTPITTTTT------------VTPTPTPTGTQTPTT-TP 3073

Query: 2029 RTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGA 2088
             T T T+ P  + +G  T  +  IT       +T   TP    T     I T   V P  
Sbjct: 3074 ITTTTTVTPTPTPTGTQTPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTP-T 3129

Query: 2089 PQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLT 2148
            P    TQ     P +T ++   TV+ TP      + T+T    ++   P     G    T
Sbjct: 3130 PTPTGTQT----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3185

Query: 2149 MAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQR 2208
               +T  T        +T      G  T     I    TV P P         P GT   
Sbjct: 3186 TTPITTTTT-------VTPTPTPTGTQTPTTTPITTTTTVTPTP--------TPTGT--- 3227

Query: 2209 FLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEA 2268
                   T  TT  TTTTTV+ T   TG Q  +            T P   +++V P   
Sbjct: 3228 ------QTPTTTPITTTTTVTPTPTPTGTQTPT------------TTPITTTTTVTPTPT 3269

Query: 2269 QPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQ 2328
               T  P+  P   T   +P      TQ    T  T ++ V     PT  Q+  P     
Sbjct: 3270 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPI 3327

Query: 2329 SQPQSNVQGQSPVRVQSPSQTRIRPS---TPSQLSPGQQSQVQ---TTTSQPIPIQPHTS 2382
            +   +     +P   Q+P+ T I  +   TP+    G Q+      TTT+   P    T 
Sbjct: 3328 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3387

Query: 2383 LQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSP 2418
             Q P+     + P   ++T T +   T  Q   ++P
Sbjct: 3388 TQTPT-----TTPITTTTTVTPTPTPTGTQTPTTTP 3418



 Score = 89.0 bits (219), Expect = 6e-17
 Identities = 128/516 (24%), Positives = 184/516 (35%), Gaps = 86/516 (16%)

Query: 1925 PTVIATSTTSPTSS---TTSTISPA------QKVMVAPISGSVT-------TGTKMVLTT 1968
            PT   T T +PT++   TT+T++P       Q     PI+ + T       TGT+   TT
Sbjct: 3151 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3210

Query: 1969 KVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQP 2028
             + +  TVT        QT  T      +             + P+ T T  QT T+  P
Sbjct: 3211 PITTTTTVTPTPTPTGTQTPTTTPITTTTT------------VTPTPTPTGTQTPTT-TP 3257

Query: 2029 RTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGA 2088
             T T T+ P  + +G  T  +  IT       +T   TP    T     I T   V P  
Sbjct: 3258 ITTTTTVTPTPTPTGTQTPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTP-T 3313

Query: 2089 PQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLT 2148
            P    TQ     P +T ++   TV+ TP      + T+T    ++   P     G    T
Sbjct: 3314 PTPTGTQT----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3369

Query: 2149 MAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQR 2208
               +T  T        +T      G  T     I    TV P P         P GT   
Sbjct: 3370 TTPITTTTT-------VTPTPTPTGTQTPTTTPITTTTTVTPTP--------TPTGT--- 3411

Query: 2209 FLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEA 2268
                   T  TT  TTTTTV+ T   TG Q  +            T P   +++V P   
Sbjct: 3412 ------QTPTTTPITTTTTVTPTPTPTGTQTPT------------TTPITTTTTVTPTPT 3453

Query: 2269 QPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQ 2328
               T  P+  P   T   +P      TQ    T  T ++ V     PT  Q+  P     
Sbjct: 3454 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPI 3511

Query: 2329 SQPQSNVQGQSPVRVQSPSQTRIRPS---TPSQLSPGQQSQVQ---TTTSQPIPIQPHTS 2382
            +   +     +P   Q+P+ T I  +   TP+    G Q+      TTT+   P    T 
Sbjct: 3512 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3571

Query: 2383 LQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSP 2418
             Q P+     + P   ++T T +   T  Q   ++P
Sbjct: 3572 TQTPT-----TTPITTTTTVTPTPTPTGTQTPTTTP 3602



 Score = 89.0 bits (219), Expect = 6e-17
 Identities = 128/516 (24%), Positives = 184/516 (35%), Gaps = 86/516 (16%)

Query: 1925 PTVIATSTTSPTSS---TTSTISPA------QKVMVAPISGSVT-------TGTKMVLTT 1968
            PT   T T +PT++   TT+T++P       Q     PI+ + T       TGT+   TT
Sbjct: 3335 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3394

Query: 1969 KVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQP 2028
             + +  TVT        QT  T      +             + P+ T T  QT T+  P
Sbjct: 3395 PITTTTTVTPTPTPTGTQTPTTTPITTTTT------------VTPTPTPTGTQTPTT-TP 3441

Query: 2029 RTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGA 2088
             T T T+ P  + +G  T  +  IT       +T   TP    T     I T   V P  
Sbjct: 3442 ITTTTTVTPTPTPTGTQTPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTP-T 3497

Query: 2089 PQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLT 2148
            P    TQ     P +T ++   TV+ TP      + T+T    ++   P     G    T
Sbjct: 3498 PTPTGTQT----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3553

Query: 2149 MAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQR 2208
               +T  T        +T      G  T     I    TV P P         P GT   
Sbjct: 3554 TTPITTTTT-------VTPTPTPTGTQTPTTTPITTTTTVTPTP--------TPTGT--- 3595

Query: 2209 FLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEA 2268
                   T  TT  TTTTTV+ T   TG Q  +            T P   +++V P   
Sbjct: 3596 ------QTPTTTPITTTTTVTPTPTPTGTQTPT------------TTPITTTTTVTPTPT 3637

Query: 2269 QPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQ 2328
               T  P+  P   T   +P      TQ    T  T ++ V     PT  Q+  P     
Sbjct: 3638 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPI 3695

Query: 2329 SQPQSNVQGQSPVRVQSPSQTRIRPS---TPSQLSPGQQSQVQ---TTTSQPIPIQPHTS 2382
            +   +     +P   Q+P+ T I  +   TP+    G Q+      TTT+   P    T 
Sbjct: 3696 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3755

Query: 2383 LQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSP 2418
             Q P+     + P   ++T T +   T  Q   ++P
Sbjct: 3756 TQTPT-----TTPITTTTTVTPTPTPTGTQTPTTTP 3786



 Score = 89.0 bits (219), Expect = 6e-17
 Identities = 128/516 (24%), Positives = 184/516 (35%), Gaps = 86/516 (16%)

Query: 1925 PTVIATSTTSPTSS---TTSTISPA------QKVMVAPISGSVT-------TGTKMVLTT 1968
            PT   T T +PT++   TT+T++P       Q     PI+ + T       TGT+   TT
Sbjct: 3519 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3578

Query: 1969 KVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQP 2028
             + +  TVT        QT  T      +             + P+ T T  QT T+  P
Sbjct: 3579 PITTTTTVTPTPTPTGTQTPTTTPITTTTT------------VTPTPTPTGTQTPTT-TP 3625

Query: 2029 RTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGA 2088
             T T T+ P  + +G  T  +  IT       +T   TP    T     I T   V P  
Sbjct: 3626 ITTTTTVTPTPTPTGTQTPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTP-T 3681

Query: 2089 PQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLT 2148
            P    TQ     P +T ++   TV+ TP      + T+T    ++   P     G    T
Sbjct: 3682 PTPTGTQT----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3737

Query: 2149 MAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQR 2208
               +T  T        +T      G  T     I    TV P P         P GT   
Sbjct: 3738 TTPITTTTT-------VTPTPTPTGTQTPTTTPITTTTTVTPTP--------TPTGT--- 3779

Query: 2209 FLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEA 2268
                   T  TT  TTTTTV+ T   TG Q  +            T P   +++V P   
Sbjct: 3780 ------QTPTTTPITTTTTVTPTPTPTGTQTPT------------TTPITTTTTVTPTPT 3821

Query: 2269 QPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQ 2328
               T  P+  P   T   +P      TQ    T  T ++ V     PT  Q+  P     
Sbjct: 3822 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPI 3879

Query: 2329 SQPQSNVQGQSPVRVQSPSQTRIRPS---TPSQLSPGQQSQVQ---TTTSQPIPIQPHTS 2382
            +   +     +P   Q+P+ T I  +   TP+    G Q+      TTT+   P    T 
Sbjct: 3880 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3939

Query: 2383 LQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSP 2418
             Q P+     + P   ++T T +   T  Q   ++P
Sbjct: 3940 TQTPT-----TTPITTTTTVTPTPTPTGTQTPTTTP 3970



 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 123/480 (25%), Positives = 170/480 (35%), Gaps = 65/480 (13%)

Query: 1925 PTVIATSTTSPTSS---TTSTISPA------QKVMVAPISGSVT-------TGTKMVLTT 1968
            PT   T T +PT++   TT+T++P       Q     PI+ + T       TGT+   TT
Sbjct: 3887 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3946

Query: 1969 KVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQP 2028
             + +  TVT        QT  T      +             + P+ T T  QT T+  P
Sbjct: 3947 PITTTTTVTPTPTPTGTQTPTTTPITTTTT------------VTPTPTPTGTQTPTT-TP 3993

Query: 2029 RTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGA 2088
             T T T+ P  + +G  T  +  IT       +T   TP    T     I T   V P  
Sbjct: 3994 ITTTTTVTPTPTPTGTQTPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTP-T 4049

Query: 2089 PQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLT 2148
            P    TQ     P +T ++   TV+ TP      + T+T    ++   P     G    T
Sbjct: 4050 PTPTGTQT----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4105

Query: 2149 MAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQR 2208
               +T  T        +T      G  T     I    TV P P         P GT Q 
Sbjct: 4106 TTPITTTTT-------VTPTPTPTGTQTPTTTPITTTTTVTPTP--------TPTGT-QT 4149

Query: 2209 FLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEA 2268
               TP+ TT T   T T T + T   T     + ++P       +T PP  +S+   AE 
Sbjct: 4150 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAEL 4209

Query: 2269 QPQTAQP-SAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAA 2327
                  P S+ PQ      SP          +   TT+ S +P   + T         A 
Sbjct: 4210 TTSNPPPESSTPQTSRSTSSP----------LTESTTLLSTLPPAIEMTSTAPPSTPTAP 4259

Query: 2328 QSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPS 2387
             +    +     P    SP  T  R +T    S    S VQTTT+      P T L  PS
Sbjct: 4260 TTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTP-TPLSTPS 4318



 Score = 75.9 bits (185), Expect = 6e-13
 Identities = 125/517 (24%), Positives = 178/517 (34%), Gaps = 73/517 (14%)

Query: 1930 TSTTSPTSSTTSTISPAQKVMVA-------PISGSVTTGTKMVLTTKVGSPATVTFQQNK 1982
            T+TT+PTSST  + +P    + +       P SGS   G +       G+P  +  +  K
Sbjct: 1284 TTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGS-DDGDRETFDGVCGAPEDIECRSVK 1342

Query: 1983 NFHQTFATWVKQGQSNS--GVVQVQQKVLGIIPSS-------------------TGTSQQ 2021
            + H +     ++ Q +   G +   +   G  P                     T  S  
Sbjct: 1343 DPHLSLEQLGQKVQCDVSVGFICKNEDQFGNGPFGLCYDYKIRVNCCWPMDKCITTPSPP 1402

Query: 2022 TFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTP 2081
            T T   P T+T T+ P T+ S  TT+ +         P +T   TP   +T    I  T 
Sbjct: 1403 TTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTT 1462

Query: 2082 VMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQ 2141
                   P    T      P +T  S P T ++TP   +  S  +T+ I   AS    P 
Sbjct: 1463 TPPPTTTPSPPTT---TPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPP 1519

Query: 2142 QGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAM 2201
                       T        +   T  I     TT     +P   T  P P         
Sbjct: 1520 TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT----TLPPTTTPSPPP----TTTTT 1571

Query: 2202 PNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSS 2261
            P  T      TP   T TT S  T T +T    T        +P        T PP  + 
Sbjct: 1572 PPPTT-----TPSPPTTTTPSPPTITTTTPPPTT--------TPSPPTTTTTTPPPTTTP 1618

Query: 2262 SVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSS 2321
            S  P    P T   S    P T   SP      T P   T +  ++  PS   P    ++
Sbjct: 1619 S--PPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS--PPITTTTT 1674

Query: 2322 KPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHT 2381
             P     S P +         + +PS T    +TPS  SP   +   ++T+ P P  P T
Sbjct: 1675 PPPTTTPSSPITTTPSPPTTTMTTPSPT----TTPS--SPITTTTTPSSTTTPSP--PPT 1726

Query: 2382 SLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSP 2418
            ++  PS   P + P   ++T T     TL   T SSP
Sbjct: 1727 TMTTPS---PTTTPSPPTTTMT-----TLPPTTTSSP 1755



 Score = 63.2 bits (152), Expect = 4e-09
 Identities = 89/379 (23%), Positives = 116/379 (30%), Gaps = 61/379 (16%)

Query: 2080 TPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPR 2139
            +P    P  P    T +    P +T  S P T ++TP   +  S   T+      +  P 
Sbjct: 1400 SPPTTTPSPPPTSTTTL----PPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS 1455

Query: 2140 PQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQA 2199
            P                         T        T       P   T  P P       
Sbjct: 1456 PPIS----------------------TTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTT 1493

Query: 2200 AMPNGTVQRFLFTPL---ATTATTASTTT----TTVSTTAAGTGEQRQSKLSPQMQVHQD 2252
              P  T      TP+   A+T T   TTT    TT +TT   T        +P       
Sbjct: 1494 PPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTST 1553

Query: 2253 KTLPPAQSSSVGPAEAQ--PQTAQPSAQPQPQTQPQSPA----QPEVQTQPEVQTQTTVS 2306
             TLPP  + S  P      P T  PS  P   T P  P      P   T P   T TT +
Sbjct: 1554 TTLPPTTTPSPPPTTTTTPPPTTTPS--PPTTTTPSPPTITTTTPPPTTTPSPPTTTTTT 1611

Query: 2307 SHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQ 2366
                +   P       P  +  + P +      P    +P  T   PS P+  +P     
Sbjct: 1612 PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT-PSPPTTTTPSPPIT 1670

Query: 2367 VQTTT------SQPI---PIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSS 2417
              TT       S PI   P  P T++  PS   P + P    +T T  S  T       +
Sbjct: 1671 TTTTPPPTTTPSSPITTTPSPPTTTMTTPS---PTTTPSSPITTTTTPSSTT-------T 1720

Query: 2418 PSRPQLQIQQPQPQVIAVP 2436
            PS P   +  P P     P
Sbjct: 1721 PSPPPTTMTTPSPTTTPSP 1739



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 93/390 (23%), Positives = 128/390 (32%), Gaps = 52/390 (13%)

Query: 1925 PTVIATSTTSPTSS-----TTSTISPAQKVMVAPISGSVT---TGTKMVLTTKVGSPATV 1976
            P    T+T  PT++     TT+T  P       PIS + T   T T    TT    P T 
Sbjct: 1424 PPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTT 1483

Query: 1977 TFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIR 2036
                         T      + + +           P+ST T   T T   P T T T  
Sbjct: 1484 PSPPTTTTTTPPPTTTPSPPTTTPITP---------PASTTTLPPTTTPSPPTTTTTTPP 1534

Query: 2037 PNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAII--RTPVMVQPGAPQQVMT 2094
            P T+ S  TT+     T     P  T    P   +T          P    P  P    T
Sbjct: 1535 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTT 1594

Query: 2095 QIIRGQPVSTAVSAPNTVSSTPGQKS---------LTSATSTSNIQSSASQPPRPQQGQV 2145
                  P +T  S P T ++TP   +         +T  TST+ +  + +  P P     
Sbjct: 1595 T----PPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTT 1650

Query: 2146 ---KLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMP 2202
                 T +  T  T     +  +T        TT         +T  P P    M    P
Sbjct: 1651 PPPTTTPSPPTTTTP----SPPITTTTTPPPTTTPS-----SPITTTPSPPTTTMTTPSP 1701

Query: 2203 NGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSS 2262
              T      +P+ TT T +STTT +   T   T     +   P   +    TLPP  +SS
Sbjct: 1702 TTTPS----SPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTM---TTLPPTTTSS 1754

Query: 2263 -VGPAEAQPQTAQPSAQPQPQTQPQSPAQP 2291
             +      P    P+  P   T P +P  P
Sbjct: 1755 PLTTTPLPPSITPPTFSPFSTTTPTTPCVP 1784



 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 39/189 (20%), Positives = 61/189 (32%), Gaps = 11/189 (5%)

Query: 2254 TLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQT------QTTVSS 2307
            T P   +++  P      T  P+  P P T   +   P     P + T       TT S 
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456

Query: 2308 HVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQV 2367
             + +   P    +  P     S P +     +      P  T   P T + ++P   +  
Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTT 1516

Query: 2368 QTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQ 2427
               T+ P P  P T+   P    P + P   ++T       T      ++PS P      
Sbjct: 1517 LPPTTTPSP--PTTTTTTP---PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTT 1571

Query: 2428 PQPQVIAVP 2436
            P P     P
Sbjct: 1572 PPPTTTPSP 1580



 Score = 38.9 bits (89), Expect = 0.075
 Identities = 35/122 (28%), Positives = 50/122 (40%), Gaps = 5/122 (4%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 4107 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4166

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKT 1699
              G+    +    + T VT T T + T TG    TS     E +T +     + S P+ +
Sbjct: 4167 PTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPP--ESSTPQTS 4224

Query: 1700 RS 1701
            RS
Sbjct: 4225 RS 4226



 Score = 37.7 bits (86), Expect = 0.17
 Identities = 50/233 (21%), Positives = 76/233 (32%), Gaps = 32/233 (13%)

Query: 1503 TLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSNDFI 1562
            T P+T    +T T TP+   P            I T+     T +P  ++  +       
Sbjct: 1894 TPPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----- 1945

Query: 1563 DENGLPINKNENVNG-------ESKRKTVITEVTTMTST---VATESKTVIKVEKGDKQT 1612
                 PI     V         ++   T IT  TT+T T     T++ T   +      T
Sbjct: 1946 -----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2000

Query: 1613 VVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVT---------TTVTD 1663
               +       T T  TTT T   TP+  G+    +    + T VT         T  T 
Sbjct: 2001 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2060

Query: 1664 SLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSS 1716
             +TTT     T      +  T   +       P  T +GT  P+     T ++
Sbjct: 2061 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2113



 Score = 37.4 bits (85), Expect = 0.22
 Identities = 42/145 (28%), Positives = 59/145 (40%), Gaps = 15/145 (10%)

Query: 1585 ITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTEN-----CAKSTVTTTTTTVTKLSTPS 1639
            +T+ TTMT+T  TE+ T          T V+ T          +T  TTTTTVT   TP 
Sbjct: 1879 VTQPTTMTTTT-TENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP- 1936

Query: 1640 TGGSVDIISVKEQSKTVV---TTTVTDSLTTTGGTLVTSMT-----VSKEYSTRDKVKLM 1691
            TG      +    + TV    T T T + TTT  T  T++T        +  T   +   
Sbjct: 1937 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 1996

Query: 1692 KFSRPKKTRSGTALPSYRKFVTKSS 1716
                P  T +GT  P+     T ++
Sbjct: 1997 TTVTPTPTPTGTQTPTTTPITTTTT 2021



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 1991 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2050

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2051 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2110

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2111 TTTVTPTPTPTGTQTPTTTPITTTTT 2136



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2014 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2073

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2074 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2133

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2134 TTTVTPTPTPTGTQTPTTTPITTTTT 2159



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2037 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2096

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 2097 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2156

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2157 TTTVTPTPTPTGTQTPTTTPITTTTT 2182



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2060 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2119

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2120 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2179

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2180 TTTVTPTPTPTGTQTPTTTPITTTTT 2205



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2083 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2142

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2143 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2202

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2203 TTTVTPTPTPTGTQTPTTTPITTTTT 2228



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2106 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2165

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 2166 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2225

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2226 TTTVTPTPTPTGTQTPTTTPITTTTT 2251



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2129 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2188

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2189 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2248

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2249 TTTVTPTPTPTGTQTPTTTPITTTTT 2274



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2152 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2211

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2212 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2271

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2272 TTTVTPTPTPTGTQTPTTTPITTTTT 2297



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2175 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2234

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 2235 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2294

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2295 TTTVTPTPTPTGTQTPTTTPITTTTT 2320



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2198 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2257

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2258 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2317

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2318 TTTVTPTPTPTGTQTPTTTPITTTTT 2343



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2221 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2280

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2281 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2340

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2341 TTTVTPTPTPTGTQTPTTTPITTTTT 2366



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2244 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2303

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 2304 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2363

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2364 TTTVTPTPTPTGTQTPTTTPITTTTT 2389



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2267 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2326

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2327 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2386

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2387 TTTVTPTPTPTGTQTPTTTPITTTTT 2412



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2290 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2349

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2409

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2410 TTTVTPTPTPTGTQTPTTTPITTTTT 2435



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2313 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2372

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 2373 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2432

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2433 TTTVTPTPTPTGTQTPTTTPITTTTT 2458



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2336 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2395

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2396 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2455

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2456 TTTVTPTPTPTGTQTPTTTPITTTTT 2481



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2359 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2418

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2419 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2478

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2479 TTTVTPTPTPTGTQTPTTTPITTTTT 2504



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2382 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2441

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 2442 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2501

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2502 TTTVTPTPTPTGTQTPTTTPITTTTT 2527



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2405 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2464

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2465 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2524

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2525 TTTVTPTPTPTGTQTPTTTPITTTTT 2550



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2428 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2487

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2488 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2547

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2548 TTTVTPTPTPTGTQTPTTTPITTTTT 2573



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2451 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2510

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 2511 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2570

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2571 TTTVTPTPTPTGTQTPTTTPITTTTT 2596



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2474 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2533

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2534 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2593

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2594 TTTVTPTPTPTGTQTPTTTPITTTTT 2619



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2497 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2556

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2557 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2616

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2617 TTTVTPTPTPTGTQTPTTTPITTTTT 2642



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2520 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2579

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 2580 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2639

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2640 TTTVTPTPTPTGTQTPTTTPITTTTT 2665



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2543 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2602

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2603 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2662

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2663 TTTVTPTPTPTGTQTPTTTPITTTTT 2688



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2566 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2625

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2626 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2685

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2686 TTTVTPTPTPTGTQTPTTTPITTTTT 2711



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2589 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2648

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 2649 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2708

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2709 TTTVTPTPTPTGTQTPTTTPITTTTT 2734



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2671

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2672 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2731

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2732 TTTVTPTPTPTGTQTPTTTPITTTTT 2757



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2635 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2694

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2695 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2754

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2755 TTTVTPTPTPTGTQTPTTTPITTTTT 2780



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2658 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2717

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 2718 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2777

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2778 TTTVTPTPTPTGTQTPTTTPITTTTT 2803



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2681 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2740

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2741 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2800

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2801 TTTVTPTPTPTGTQTPTTTPITTTTT 2826



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2704 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2763

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2764 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2823

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2824 TTTVTPTPTPTGTQTPTTTPITTTTT 2849



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2727 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2786

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 2787 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2846

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2847 TTTVTPTPTPTGTQTPTTTPITTTTT 2872



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2750 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2809

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2810 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2869

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2870 TTTVTPTPTPTGTQTPTTTPITTTTT 2895



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2773 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2832

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2833 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2892

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2893 TTTVTPTPTPTGTQTPTTTPITTTTT 2918



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2796 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2855

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 2856 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2915

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2916 TTTVTPTPTPTGTQTPTTTPITTTTT 2941



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2819 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2878

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2879 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2938

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2939 TTTVTPTPTPTGTQTPTTTPITTTTT 2964



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2842 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2901

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2902 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2961

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2962 TTTVTPTPTPTGTQTPTTTPITTTTT 2987



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2865 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2924

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 2925 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2984

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 2985 TTTVTPTPTPTGTQTPTTTPITTTTT 3010



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2888 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2947

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2948 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3007

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3008 TTTVTPTPTPTGTQTPTTTPITTTTT 3033



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2911 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2970

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 2971 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3030

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3031 TTTVTPTPTPTGTQTPTTTPITTTTT 3056



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2934 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2993

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 2994 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3053

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3054 TTTVTPTPTPTGTQTPTTTPITTTTT 3079



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2957 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3016

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3017 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3076

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3077 TTTVTPTPTPTGTQTPTTTPITTTTT 3102



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 2980 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3039

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3040 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3099

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3100 TTTVTPTPTPTGTQTPTTTPITTTTT 3125



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3003 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3062

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 3063 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3122

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3123 TTTVTPTPTPTGTQTPTTTPITTTTT 3148



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3026 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3085

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3086 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3145

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3146 TTTVTPTPTPTGTQTPTTTPITTTTT 3171



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3049 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3108

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3109 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3168

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3169 TTTVTPTPTPTGTQTPTTTPITTTTT 3194



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3072 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3131

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 3132 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3191

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3192 TTTVTPTPTPTGTQTPTTTPITTTTT 3217



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3095 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3154

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3155 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3214

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3215 TTTVTPTPTPTGTQTPTTTPITTTTT 3240



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3118 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3177

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3178 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3237

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3238 TTTVTPTPTPTGTQTPTTTPITTTTT 3263



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3141 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3200

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 3201 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3260

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3261 TTTVTPTPTPTGTQTPTTTPITTTTT 3286



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3164 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3223

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3224 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3283

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3284 TTTVTPTPTPTGTQTPTTTPITTTTT 3309



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3187 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3246

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3247 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3306

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3307 TTTVTPTPTPTGTQTPTTTPITTTTT 3332



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3210 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3269

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 3270 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3329

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3330 TTTVTPTPTPTGTQTPTTTPITTTTT 3355



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3233 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3292

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3293 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3352

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3353 TTTVTPTPTPTGTQTPTTTPITTTTT 3378



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3256 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3315

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3316 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3375

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3376 TTTVTPTPTPTGTQTPTTTPITTTTT 3401



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3279 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3338

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 3339 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3398

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3399 TTTVTPTPTPTGTQTPTTTPITTTTT 3424



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3302 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3361

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3362 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3421

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3422 TTTVTPTPTPTGTQTPTTTPITTTTT 3447



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3325 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3384

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3385 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3444

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3445 TTTVTPTPTPTGTQTPTTTPITTTTT 3470



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3348 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3407

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 3408 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3467

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3468 TTTVTPTPTPTGTQTPTTTPITTTTT 3493



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3371 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3430

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3431 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3490

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3491 TTTVTPTPTPTGTQTPTTTPITTTTT 3516



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3394 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3453

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3454 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3513

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3514 TTTVTPTPTPTGTQTPTTTPITTTTT 3539



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3417 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3476

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 3477 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3536

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3537 TTTVTPTPTPTGTQTPTTTPITTTTT 3562



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3440 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3499

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3500 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3559

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3560 TTTVTPTPTPTGTQTPTTTPITTTTT 3585



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3463 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3522

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3523 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3582

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3583 TTTVTPTPTPTGTQTPTTTPITTTTT 3608



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3486 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3545

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 3546 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3605

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3606 TTTVTPTPTPTGTQTPTTTPITTTTT 3631



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3509 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3568

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3569 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3628

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3629 TTTVTPTPTPTGTQTPTTTPITTTTT 3654



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3532 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3591

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3592 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3651

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3652 TTTVTPTPTPTGTQTPTTTPITTTTT 3677



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3555 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3614

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 3615 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3674

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3675 TTTVTPTPTPTGTQTPTTTPITTTTT 3700



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3578 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3637

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3638 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3697

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3698 TTTVTPTPTPTGTQTPTTTPITTTTT 3723



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3601 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3660

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3661 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3720

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3721 TTTVTPTPTPTGTQTPTTTPITTTTT 3746



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3624 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3683

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 3684 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3743

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3744 TTTVTPTPTPTGTQTPTTTPITTTTT 3769



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3647 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3706

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3707 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3766

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3767 TTTVTPTPTPTGTQTPTTTPITTTTT 3792



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3670 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3729

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3730 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3789

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3790 TTTVTPTPTPTGTQTPTTTPITTTTT 3815



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3693 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3752

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 3753 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3812

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3813 TTTVTPTPTPTGTQTPTTTPITTTTT 3838



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3716 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3775

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3776 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3835

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3836 TTTVTPTPTPTGTQTPTTTPITTTTT 3861



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3739 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3798

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3799 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3858

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3859 TTTVTPTPTPTGTQTPTTTPITTTTT 3884



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3762 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3821

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 3822 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3881

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3882 TTTVTPTPTPTGTQTPTTTPITTTTT 3907



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3785 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3844

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3845 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3904

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3905 TTTVTPTPTPTGTQTPTTTPITTTTT 3930



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3808 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3867

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3868 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3927

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3928 TTTVTPTPTPTGTQTPTTTPITTTTT 3953



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3831 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3890

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 3891 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3950

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3951 TTTVTPTPTPTGTQTPTTTPITTTTT 3976



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3854 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3913

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3914 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3973

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3974 TTTVTPTPTPTGTQTPTTTPITTTTT 3999



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3877 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3936

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3937 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3996

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 3997 TTTVTPTPTPTGTQTPTTTPITTTTT 4022



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3900 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3959

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 3960 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4019

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 4020 TTTVTPTPTPTGTQTPTTTPITTTTT 4045



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3923 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3982

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 3983 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4042

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 4043 TTTVTPTPTPTGTQTPTTTPITTTTT 4068



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3946 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4005

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 4006 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4065

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 4066 TTTVTPTPTPTGTQTPTTTPITTTTT 4091



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3969 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4028

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 4029 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4088

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 4089 TTTVTPTPTPTGTQTPTTTPITTTTT 4114



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 3992 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4051

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 4052 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4111

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 4112 TTTVTPTPTPTGTQTPTTTPITTTTT 4137



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 4015 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4074

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT--LVTSMTVSK-------EYSTRDKVKL 1690
              G+    +    + T VT T T + T T  T  + T+ TV+        +  T   +  
Sbjct: 4075 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4134

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 4135 TTTVTPTPTPTGTQTPTTTPITTTTT 4160



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 35/146 (23%), Positives = 51/146 (34%), Gaps = 12/146 (8%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 4038 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4097

Query: 1640 TGGSVDIISVKEQSKTVVT---------TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT         T  T  +TTT     T      +  T   +  
Sbjct: 4098 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4157

Query: 1691 MKFSRPKKTRSGTALPSYRKFVTKSS 1716
                 P  T +GT  P+     T ++
Sbjct: 4158 TTTVTPTPTPTGTQTPTTTPITTTTT 4183



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 40/164 (24%), Positives = 64/164 (39%), Gaps = 12/164 (7%)

Query: 1925 PTVIATSTTSPTSS---TTSTISPAQKVMVAPISGSVTTGTKMV--LTTKVGSPATVTFQ 1979
            PT   T T +PT++   TT+T++P              T T  +  LTT    P + T Q
Sbjct: 4163 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQ 4222

Query: 1980 QNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFT---SFQPRTATVTIR 2036
             +++          +  +    +    ++    P ST T+  T +   +  P  +T T  
Sbjct: 4223 TSRSTSSPLT----ESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSP 4278

Query: 2037 PNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRT 2080
            P T   G TT +S   T   ++   T   TP        +IIRT
Sbjct: 4279 PGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRT 4322



 Score = 36.2 bits (82), Expect = 0.49
 Identities = 20/55 (36%), Positives = 25/55 (45%), Gaps = 10/55 (18%)

Query: 2664 TAVAAPCPPVTPAP----PAPPAPPPSPP------PPPAVQHTGLLSTPTLPAAS 2708
            +    P P  TP+P    P+PP   PSPP      PPP    +   +TP  P AS
Sbjct: 1459 STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAS 1513



 Score = 35.0 bits (79), Expect = 1.1
 Identities = 22/83 (26%), Positives = 30/83 (36%), Gaps = 15/83 (18%)

Query: 8    PPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSP 67
            P   P+ P      P P   P PPT+ PI                       P T   SP
Sbjct: 1519 PTTTPSPPTTTTTTPPPTTTPSPPTTTPI--------------TPPTSTTTLPPTTTPSP 1564

Query: 68   RGGSSSRRKPPPPPPAPPSTSAP 90
               +++   PP   P+PP+T+ P
Sbjct: 1565 -PPTTTTTPPPTTTPSPPTTTTP 1586



 Score = 35.0 bits (79), Expect = 1.1
 Identities = 22/83 (26%), Positives = 30/83 (36%), Gaps = 15/83 (18%)

Query: 8    PPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSP 67
            P   P+ P      P P   P PPT+ PI                       P T   SP
Sbjct: 1598 PTTTPSPPTTTTTTPPPTTTPSPPTTTPI--------------TPPTSTTTLPPTTTPSP 1643

Query: 68   RGGSSSRRKPPPPPPAPPSTSAP 90
               +++   PP   P+PP+T+ P
Sbjct: 1644 -PPTTTTTPPPTTTPSPPTTTTP 1665



 Score = 34.3 bits (77), Expect = 1.9
 Identities = 22/81 (27%), Positives = 32/81 (39%), Gaps = 15/81 (18%)

Query: 8    PPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSP 67
            P   P+ P      P P   P PPT+ PI                A+   + P T  S P
Sbjct: 1480 PTTTPSPPTTTTTTPPPTTTPSPPTTTPITP-------------PASTTTLPPTTTPSPP 1526

Query: 68   RGGSSSRRKPPPPPPAPPSTS 88
               +++   PP   P+PP+T+
Sbjct: 1527 T--TTTTTPPPTTTPSPPTTT 1545



 Score = 34.3 bits (77), Expect = 1.9
 Identities = 20/75 (26%), Positives = 29/75 (38%), Gaps = 5/75 (6%)

Query: 2664 TAVAAPCPPVTPAPPAPPAPPP-----SPPPPPAVQHTGLLSTPTLPAASQKRKREEEKD 2718
            T    P P  TP+PP    P P     + PPP     + + +TP+ P  +          
Sbjct: 1646 TTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTP 1705

Query: 2719 SSSKSKKKKMISTTS 2733
            SS  +      STT+
Sbjct: 1706 SSPITTTTTPSSTTT 1720



 Score = 33.9 bits (76), Expect = 2.4
 Identities = 17/43 (39%), Positives = 19/43 (44%), Gaps = 6/43 (13%)

Query: 2669 PCPPVTPAPPAPPAPPPSPP------PPPAVQHTGLLSTPTLP 2705
            P PP T     PP   PSPP      PPP    +  +ST T P
Sbjct: 1422 PSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTP 1464



 Score = 33.9 bits (76), Expect = 2.4
 Identities = 16/46 (34%), Positives = 21/46 (45%), Gaps = 6/46 (13%)

Query: 2669 PCPPVTPAPPAPPAPPPSPP------PPPAVQHTGLLSTPTLPAAS 2708
            P PP+T     PP   PSPP      PPP    +   +TP+ P  +
Sbjct: 1438 PSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTT 1483



 Score = 33.9 bits (76), Expect = 2.4
 Identities = 52/217 (23%), Positives = 68/217 (31%), Gaps = 30/217 (13%)

Query: 1500 SLETLPSTKESD---STQTTTPSASCPESNSVNQVEDMEIETSEVKKVT--SSPITSEEE 1554
            S  TLP T       +T TT P  + P   +        I T+     T  S P T+   
Sbjct: 1552 STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTT 1611

Query: 1555 SNLSNDFIDENGLPINKNENVNGESKRKTVITEVTTMTS----------TVATESKTVIK 1604
               +         PI    +        T     TT T+          T  T S  +  
Sbjct: 1612 PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITT 1671

Query: 1605 VEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDS 1664
                   T  SS      S  TTT TT +  +TPS               + +TTT T S
Sbjct: 1672 TTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPS---------------SPITTTTTPS 1716

Query: 1665 LTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRS 1701
             TTT     T+MT     +T         + P  T S
Sbjct: 1717 STTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTS 1753



 Score = 33.9 bits (76), Expect = 2.4
 Identities = 33/133 (24%), Positives = 46/133 (34%), Gaps = 12/133 (9%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T   +      T   +       T T  TTT T   TP+
Sbjct: 4061 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4120

Query: 1640 TGGSVDIISVKEQSKTVVTTT---------VTDSLTTTGGTLVTSMTVSKEYSTRDKVKL 1690
              G+    +    + T VT T          T  +TTT     T      +  T   +  
Sbjct: 4121 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4180

Query: 1691 MKFSRPKKTRSGT 1703
                 P  T +GT
Sbjct: 4181 TTTVTPTPTPTGT 4193



 Score = 32.7 bits (73), Expect = 5.4
 Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 4/41 (9%)

Query: 2669 PCPPV----TPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLP 2705
            P PP+    TP P   P+PP + P PP    +   +T T P
Sbjct: 1454 PSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTP 1494



 Score = 32.3 bits (72), Expect = 7.0
 Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 13/53 (24%)

Query: 2666 VAAPCPPVT-PAPPA------PPAPPPSPP------PPPAVQHTGLLSTPTLP 2705
            +  P PP T P+PP       PP   PSPP      PPP    +  ++T T P
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTP 1448



 Score = 32.3 bits (72), Expect = 7.0
 Identities = 20/64 (31%), Positives = 23/64 (35%), Gaps = 19/64 (29%)

Query: 2664 TAVAAPCPPVTPAPPA-------------PPAPPPSPP------PPPAVQHTGLLSTPTL 2704
            T    P P  TP+PP              PP   PSPP      PPP    +   +TP  
Sbjct: 1489 TTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1548

Query: 2705 PAAS 2708
            P  S
Sbjct: 1549 PPTS 1552



 Score = 32.0 bits (71), Expect = 9.2
 Identities = 20/65 (30%), Positives = 23/65 (35%), Gaps = 20/65 (30%)

Query: 2664 TAVAAPCPPVTPAPPA--------------PPAPPPSPP------PPPAVQHTGLLSTPT 2703
            T    P P  TP+PP               PP   PSPP      PPP    +   +TP 
Sbjct: 1567 TTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1626

Query: 2704 LPAAS 2708
             P  S
Sbjct: 1627 TPPTS 1631



 Score = 32.0 bits (71), Expect = 9.2
 Identities = 17/41 (41%), Positives = 19/41 (46%), Gaps = 4/41 (9%)

Query: 2669 PCPPVTPAPP----APPAPPPSPPPPPAVQHTGLLSTPTLP 2705
            P P  TP+PP      P P  +P PP     T   ST TLP
Sbjct: 1596 PPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP 1636


>gi|148612882 cat eye syndrome chromosome region, candidate 2 [Homo
            sapiens]
          Length = 1484

 Score = 88.6 bits (218), Expect = 8e-17
 Identities = 67/220 (30%), Positives = 102/220 (46%), Gaps = 30/220 (13%)

Query: 2701 TPTLPAAS-QKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGC 2759
            TP L     QKRK EEE+     + +KK      KE +K        +   ++ K   G 
Sbjct: 320  TPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERK--------RELEEKVKAVEGM 371

Query: 2760 DRCQNWYHGRCVG-------------------ILQSEAELIDE--YVCPQCQSTEDAMTV 2798
               +  + G C+                    +L    EL  E  ++ P     E+  T 
Sbjct: 372  CSVRVVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKELPPELSHLDPNSPMREEKKTK 431

Query: 2799 LTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRR 2858
                 + D+  + +VL  ++AHK +WPFLEPVD + AP+YY +IK PMD+++ME+++   
Sbjct: 432  DLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGG 491

Query: 2859 YYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFF 2898
             Y    EFV DM  +F NCR YN   S + + ++ LE  F
Sbjct: 492  LYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCF 531



 Score = 32.3 bits (72), Expect = 7.0
 Identities = 29/102 (28%), Positives = 37/102 (36%), Gaps = 5/102 (4%)

Query: 3   GRRGRPPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEV---A 59
           G  G   + P  P  E+    P P   P T G +   R         +W      +    
Sbjct: 796 GNHGATNQGPLGPD-EKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPHGV 854

Query: 60  PKTRLSSPRGGSSSRRKPPPPPPAPPST-SAPGRGGRGGGGG 100
           P +    P   S+  R  PPP PAP S   AP +  RG  GG
Sbjct: 855 PSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGG 896


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 88.2 bits (217), Expect = 1e-16
 Identities = 275/1316 (20%), Positives = 450/1316 (34%), Gaps = 262/1316 (19%)

Query: 1202 EPSKSKTKGNDFFIDDSKLASADDIGTLICKNKKPLIQEESDT----------------- 1244
            E S S T   D  +  S  +    + T I  +  P+   E+ T                 
Sbjct: 2492 EASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTE 2551

Query: 1245 IVSSSKSALHSSVPKSTNDRDATPLSRAMDFEGKLGCDSESNSTLENSSDTVSIQDSSEE 1304
            I SS+ SA  +S+P ST    +TPL R+M    K    SE+ STL  +    SI      
Sbjct: 2552 ISSSATSAEGTSMPTSTYSEGSTPL-RSMPVSTKPLASSEA-STLSTTPVDTSIP----- 2604

Query: 1305 DMIVQNSNESISEQFRTREQDVEVLEPLKCELVSGESTGNCEDRLPVKGTEANGKKPSQQ 1364
               V  S E+ S     ++  + +  P +   VS   T      +PV  +EA+       
Sbjct: 2605 ---VTTSTETSSSPTTAKDTSMPISTPSE---VSTSLTSILVSTMPVASSEAS------- 2651

Query: 1365 KKLEERPVNKCSDQIKLKNTTDKKNNENRESEKKGQRTSTFQINGKDNKPKIYLKGECLK 1424
              L   PV    D   L  T+   ++    +E     TST    G+ + P        L 
Sbjct: 2652 -TLSTTPV----DTRTLVTTSTGTSSSPTTAEGSSMPTST---PGERSTP--------LT 2695

Query: 1425 EISESRVVSGNVEPKVNNINKIIPENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETK 1484
             I  S  +  N E    +   +                                   +T 
Sbjct: 2696 NILVSTTLLANSEASTLSTTPV-----------------------------------DTS 2720

Query: 1485 SHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSEVKKV 1544
            + + +S++A  +        P+T E  S + +TPS       S+  V  + + +SE   V
Sbjct: 2721 TPVTTSAEASSS--------PTTAEGTSMRISTPSDGSTPLTSI-LVSTLPVASSEASTV 2771

Query: 1545 ------TSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVITEVTTMTSTVATE 1598
                  TS P+T+  E++ S    +   +P +        S+  T +T +    + VA+ 
Sbjct: 2772 STTAVDTSIPVTTSTEASSSPTTAEVTSMPTST------PSETSTPLTSMPVNHTPVASS 2825

Query: 1599 SKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISV--------K 1650
                +     D  T V+ T   A S+ TT    V  +ST S G ++ + S+         
Sbjct: 2826 EAGTLSTTPVDTSTPVT-TSTKASSSPTTAEGIVVPISTASEGSTL-LTSIPVSTTPVAS 2883

Query: 1651 EQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRK 1710
             ++ T+ TT V  S+  T  T  +S   + E ++       + S P  +   + +P    
Sbjct: 2884 SEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVP---- 2939

Query: 1711 FVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYR 1770
             V  S   ++   P D    +         P         +     P  R T        
Sbjct: 2940 -VAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPIST---PGERRT-------- 2987

Query: 1771 LQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTTEI-IKRRDVGP 1829
               + S++  ++ +    AS      A  + P   +T   +S T    T I I     G 
Sbjct: 2988 --PLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGS 3045

Query: 1830 YGIRSEYCIRKIICPIGVPE--TPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWV 1887
              + S   I     P+ +PE  T   TP      + +S      P TP +   + I T+ 
Sbjct: 3046 TPLTS---IPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSP-TPAEGTSMPISTY- 3100

Query: 1888 AEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATS----------TTSPTS 1937
            +E    L  +      V    + A+   +   ++   P   +T           T+ PTS
Sbjct: 3101 SEGSTPLTGVPVSTTPVT---SSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTS 3157

Query: 1938 -----STTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWV 1992
                 ST  T  P   ++V     S  + T +  +T V +    T            +  
Sbjct: 3158 TPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTP 3217

Query: 1993 KQGQ--------SNSGVVQVQQKVLGIIP--SSTGTSQQTFTSFQPRTATVTIRPNTSGS 2042
             +G         SN+ V   +  +L   P  S+T  +  T  S  P TA  T  P ++ S
Sbjct: 3218 SEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPS 3277

Query: 2043 GGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPV 2102
             G+T  + +       P  T      + STL      TP       P    +Q     P+
Sbjct: 3278 EGSTPLTSM-------PVSTTTVASSETSTLST----TPA--DTSTPVTTYSQASSSPPI 3324

Query: 2103 STAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGN 2162
            +   S P +  S         + ST+ + SS +             +   T+ +      
Sbjct: 3325 ADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTA 3384

Query: 2163 QGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTAS 2222
            +G ++      + T  L                   A+MP  T      TP+ ++     
Sbjct: 3385 EGTSIPTSSPSEGTTPL-------------------ASMPVST------TPVVSSEVNTL 3419

Query: 2223 TTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVG--PAEAQPQTAQPSAQPQ 2280
            +TT   S T   T  +  S  SP +    + T  P  ++S G  P    P +  P A  +
Sbjct: 3420 STTPVDSNTLVTTSTEASS--SPTIA---EGTSLPTSTTSEGSTPLSIMPLSTTPVASSE 3474

Query: 2281 PQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNV-QGQS 2339
              T   +P          V T T V++  P+ + PT A+ +       S P S   +G +
Sbjct: 3475 ASTLSTTP----------VDTSTPVTTSSPTNSSPTTAEVT-------SMPTSTAGEGST 3517

Query: 2340 PVRVQSPSQTRIRPSTPSQLS--PGQQSQVQTTTSQ----PIPIQPHTS-LQIPSQGQPQ 2392
            P+     S T +  S  S LS  P   +   T++SQ    P  +Q  T  +  PS+G   
Sbjct: 3518 PLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSS 3577

Query: 2393 SQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQP------------QPQVIAVP 2436
                + SST   SS         S+PS P +    P             P+VI +P
Sbjct: 3578 LTTMLLSSTYVTSS-------EASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLP 3626



 Score = 84.0 bits (206), Expect = 2e-15
 Identities = 206/940 (21%), Positives = 322/940 (34%), Gaps = 147/940 (15%)

Query: 1505 PSTKESDSTQTTTPSA-SCPESN---SVNQVEDMEIET-SEVKKVTSSPITSEEESNLSN 1559
            P+T E  S   + PS  S P +    SV  V   E  T S     T+ P+ +  E++ S 
Sbjct: 257  PTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSP 316

Query: 1560 DFIDENGLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVS-STE 1618
               +   +P +        ++  T +T     T  VAT   + + +   D  T+V+ STE
Sbjct: 317  TTAEGTSIPTSTY------TEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTE 370

Query: 1619 NCAKSTVTTTTT----TVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVT 1674
              +  T    T+    T+++ STP T   V  I V     +  +T   DS T     + T
Sbjct: 371  PSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKT----FVTT 426

Query: 1675 SMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARK 1734
            +   S   +T +   +   +  + +   T++P     V  S   ++   P D   ++   
Sbjct: 427  ASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTS 486

Query: 1735 GGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWD 1794
                  P       P  ++   P+  P+ G        T  +   VS M           
Sbjct: 487  TEASSSP-------PTAEVNSMPTSTPSEG-------STPLTSMSVSTM----------- 521

Query: 1795 DMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVP-ETPKE 1853
             +A+       TT  +TS T +TT+         P G               +P  TP E
Sbjct: 522  PVASSEASTLSTTPVDTS-TPVTTSSEASSSSTTPEG-------------TSIPTSTPSE 567

Query: 1854 TPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVE 1913
              TP      S+ L      +   T P    T+V     E       AE      +   E
Sbjct: 568  GSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSS-EASSSSTTAEGTSMPTSTYSE 626

Query: 1914 QQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSP 1973
            +           T ++ STT   SS  ST+S        P++ S T  T    T +  S 
Sbjct: 627  RGT-------TITSMSVSTTLVASSEASTLSTTPVDSNTPVTTS-TEATSSSTTAEGTSM 678

Query: 1974 ATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFT--SFQPRTA 2031
             T T+ +                + + V   +   L   P  T T   T T  S  P TA
Sbjct: 679  PTSTYTEGS------TPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTA 732

Query: 2032 TVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQ 2091
                 P ++ S G+T  + +       P    + T  + STL    + T   +       
Sbjct: 733  DGASMPTSTPSEGSTPLTSM-------PVSKTLLTSSEASTLSTTPLDTSTHITTSTEAS 785

Query: 2092 VMTQIIRG--QPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTM 2149
                   G   P+ST       ++S P   S+T  TS     S+ S  P      V  + 
Sbjct: 786  CSPTTTEGTSMPISTPSEGSPLLTSIP--VSITPVTSPE--ASTLSTTPVDSNSPVTTST 841

Query: 2150 AQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRF 2209
               +  T   G +   +   +G+   T                       +MP  T    
Sbjct: 842  EVSSSPTPAEGTSMPTSTYSEGRTPLT-----------------------SMPVST---- 874

Query: 2210 LFTPLATTA-TTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEA 2268
              T +AT+A +T STT    ST    + E R S  + +       T  P + S+  P  +
Sbjct: 875  --TLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTST--PGEGST--PLTS 928

Query: 2269 QPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQ 2328
             P +  P    + +T   +P    V T   V T T  +S  P+ A+ T   +S P     
Sbjct: 929  MPDSTTPVVSSEARTLSATP----VDTSTPVTTSTEATSS-PTTAEGTSIPTSTPS---- 979

Query: 2329 SQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLS--PGQQSQVQTTT---SQPIPIQPHTSL 2383
                   +G +P+     S T +  S  S LS  P   +   TT+   S P P    TS+
Sbjct: 980  -------EGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSM 1032

Query: 2384 --QIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRP 2421
                PS+G         S+T   SS  +    T +  S P
Sbjct: 1033 PTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTP 1072



 Score = 82.0 bits (201), Expect = 8e-15
 Identities = 203/957 (21%), Positives = 347/957 (36%), Gaps = 137/957 (14%)

Query: 1500 SLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSEVKK------VTSSPITSEE 1553
            ++ + P+  E  S   +TPS       S+  V    + +SE+        VTS+P+T+  
Sbjct: 1491 AVSSSPTPAEGTSIAISTPSEGSTALTSI-PVSTTTVASSEINSLSTTPAVTSTPVTTYS 1549

Query: 1554 ESNLSNDFIDENGLPINKNENVNGESKRKTVITEVTTMTS-TVATESKTVIKVEKGDKQT 1612
            +++ S    D   +        +  S+  T +T +   T   V++E+ T+       K  
Sbjct: 1550 QASSSPTTADGTSM------QTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQ 1603

Query: 1613 VVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTT---- 1668
            V +STE  + +T   ++ T+   STPS G    +++    S T V +    +L+TT    
Sbjct: 1604 VTASTEASSSTTAEGSSMTI---STPSEGSP--LLTSIPVSTTPVASPEASTLSTTPVDS 1658

Query: 1669 GGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDL 1728
               ++TS  VS   +  +   +   +  +     T++      V  S+  ++   P D+ 
Sbjct: 1659 NSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNS 1718

Query: 1729 KKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLW 1788
              +      R  P  +            P+  P+ G T          L  + +    + 
Sbjct: 1719 TPVTTSTEARSSPTTSEGTS-------MPNSTPSEGTT---------PLTSIPVSTTPVL 1762

Query: 1789 ASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVP 1848
            +S   +     A P   +T   TS TE T++         P    SE             
Sbjct: 1763 SS---EASTLSATPIDTSTPVTTS-TEATSSPTTAEGTSIPTSTLSEGM----------- 1807

Query: 1849 ETPKETPTPQRKGLRSSALRPKRPETPKQTG-PVIIETWVAEEELELWEIRAFAERVEKE 1907
             TP  T TP    L +++       TP  +  PV+  T V+       E  + A     E
Sbjct: 1808 -TPL-TSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPA-EGTSIATSTPSE 1864

Query: 1908 KAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPI------SGSVTT- 1960
             + A+             T I  STT+  SS T+T+S    V   P+      S S TT 
Sbjct: 1865 GSTAL-------------TSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTA 1911

Query: 1961 -GTKMVLTT-KVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGT 2018
             G+ M  +T + G P   +                   S + V   +   L    + T T
Sbjct: 1912 DGSSMPTSTPREGRPPLTSIPV----------------STTTVASSEINTLSTTLADTRT 1955

Query: 2019 SQQTFT--SFQPRTATVTIRPNTSGSGGTT-------SNSQVITGPQIRPGMTVI--RTP 2067
               T++  S  P TA  T  P  + S G+T       S + V++        T +   TP
Sbjct: 1956 PVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTP 2015

Query: 2068 LQQSTLGKAIIRTP--VMVQPGAPQQVMTQIIRGQPVSTAV---SAPNTVSSTPGQKSL- 2121
               ST G +   T     +Q   P +  T +  G PVST +   S  NT+S+TP      
Sbjct: 2016 ATTSTEGSSSPTTAGGTSIQTSTPSERTTPLA-GMPVSTTLVVSSEGNTLSTTPVDSKTQ 2074

Query: 2122 ----TSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTG 2177
                T A+S++  + S+     P +G   LT   L+  T      +  T+        + 
Sbjct: 2075 VTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLS--TTPVASPEASTLSTTPVDSNSP 2132

Query: 2178 QLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGE 2237
             +       + +P  G   MQ +  +         P++TT   AS+  +T+STT   T  
Sbjct: 2133 VITSTEVSSSPIPTEGTS-MQTSTYSDRRTPLTSMPVSTTVV-ASSAISTLSTTPVDTS- 2189

Query: 2238 QRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQP 2297
                  +P     + ++ P     +  P     + + P       T P   ++    +  
Sbjct: 2190 ------TPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSAT 2243

Query: 2298 EVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQ---PQSNVQGQSPV----RVQSPSQTR 2350
             V T T V++   + + PT A+ +    +  S+   P +++     +     V + S T 
Sbjct: 2244 PVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTP 2303

Query: 2351 IRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQS-STQTLSS 2406
            +  +TP   S    S   T     +P    +    P    P S   V S  T TLS+
Sbjct: 2304 VDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLST 2360



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 265/1298 (20%), Positives = 456/1298 (35%), Gaps = 170/1298 (13%)

Query: 1244 TIVSSSKSALHSSVPKSTN---DRDATPLSRA-MDFEGKLGCDSESNS---TLE-NSSDT 1295
            T   S  S   +S+P ST      +A+ LS   +D + ++   +E++S   T E NS  T
Sbjct: 444  TSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPT 503

Query: 1296 VSIQDSSEE--DMIVQNSNESISEQFRTREQDVEVLEPLKCELVSGESTGNCEDRLPVKG 1353
             +  + S     M V     + SE        V+   P+     +  S+   E       
Sbjct: 504  STPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTS 563

Query: 1354 TEANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNNENRESEKKGQRTSTFQINGKDNK 1413
            T + G  P     +  R V   S +    +TT   +N    +  +   +ST    G    
Sbjct: 564  TPSEGSTPLTNMPVSTRLV--VSSEASTTSTTPADSNTFVTTSSEASSSST-TAEGTSMP 620

Query: 1414 PKIYL-KGECLKEISESRVVSGNVEPKVNNINKIIPENDIKSLTVKESAIRPFINGDVIM 1472
               Y  +G  +  +S S  +  + E    +   +     + + T   S+        +  
Sbjct: 621  TSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPT 680

Query: 1473 EDFNERNSSETK----SHLLSSSDAEGNYRDSLET---LPSTKESDSTQTTTPSASCPES 1525
              + E ++  T     + L++SS+A       ++T   + ++ E+ S+ TT   AS P S
Sbjct: 681  STYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTS 740

Query: 1526 NSVNQVEDMEIETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVI 1585
                    +   TS    V+ + +TS E S LS   +D +      +   + E+      
Sbjct: 741  TPSEGSTPL---TS--MPVSKTLLTSSEASTLSTTPLDTS-----THITTSTEASCSPTT 790

Query: 1586 TEVTTMTSTVATESKTVIKVEKGDKQTVVS------STENCAKSTVTTTTTTVTKLSTPS 1639
            TE T+M  +  +E   ++         V S      ST     ++  TT+T V+   TP+
Sbjct: 791  TEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPA 850

Query: 1640 TGGSVDIISVKEQ---------SKTVVTTTVTDSLTTTG---GTLVTSMTVSKEYSTRDK 1687
             G S+   +  E          S T+V T+   +L+TT     T VT+ T ++   T  +
Sbjct: 851  EGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSE 910

Query: 1688 VKLMKFSRPKKTRSG-TALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYN 1746
               M  S P +  +  T++P     V  S  +++   P D    +         P     
Sbjct: 911  GTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSP----- 965

Query: 1747 AKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWAS------LRWDDMAAKA 1800
                 +    P+  P+ G T         +L   S    L          L     A+  
Sbjct: 966  --TTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSP 1023

Query: 1801 PPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTP--- 1857
            PP    T   TS     +T + +          SE           +  TP +T TP   
Sbjct: 1024 PPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETST--------LSTTPADTSTPVTT 1075

Query: 1858 --QRKGLRSSALRPKRP-------ETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEK 1908
              Q     ++A     P        TP  + PV     V+ E   L         V+   
Sbjct: 1076 YSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTL-----STTPVDTSI 1130

Query: 1909 AQAVEQQAKKRLEQQKPTVIATSTTS---------PTSSTTSTISPAQKVMVAPISGSVT 1959
                  +A       + T I TS  S         P S+T    S A  +   P+     
Sbjct: 1131 PVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSK-- 1188

Query: 1960 TGTKMVLTTKVGSP---ATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSST 2016
              T++  +T+  SP   A VT        +           ++ V   +   L   P  T
Sbjct: 1189 --TQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDT 1246

Query: 2017 GTSQQTF--TSFQPRTATVTIRPNTSGSGGTT------SNSQVITGPQIRPGMTVIRTPL 2068
             T   T   TS  P TA  T  P ++ S G+T       ++ ++T P+     T++ TP+
Sbjct: 1247 STPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPE---ASTLLTTPV 1303

Query: 2069 QQSTLGKAIIRTPVMVQP----GAPQQVMTQI-----IRGQPVSTAVSAPNTVS------ 2113
               T G  +    V   P    G      T       +   PV+T + A + +S      
Sbjct: 1304 --DTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTP 1361

Query: 2114 ---STPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTM--AQLTQLTQGHGGNQGLTVV 2168
               STP   S  + +S +  + ++     P +G   LT      T +          T V
Sbjct: 1362 VDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPV 1421

Query: 2169 -IQGQGQTTGQLQLIP---QGVTV---LPGPGQ-QLMQAAMPNGTVQRFLFTPLATTATT 2220
                 G T+ +    P   +G+++    P  G+  L    + N  V     + L+TT   
Sbjct: 1422 DTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVD 1481

Query: 2221 AST--TTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQ 2278
            +++   T+T  +++    E     +S   +     T  P  +++V  +E    +  P+  
Sbjct: 1482 SNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVT 1541

Query: 2279 PQP-QTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQP---------------THAQSSK 2322
              P  T  Q+ + P       +QT T      P  + P               T    SK
Sbjct: 1542 STPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSK 1601

Query: 2323 PQVAAQSQPQSNVQGQ-SPVRVQSPSQ-TRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPH 2380
             QV A ++  S+   + S + + +PS+ + +  S P   +P    +  T ++ P+     
Sbjct: 1602 TQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSP 1661

Query: 2381 --TSLQIPSQGQPQSQPQVQSSTQTLSSGQT-LNQVTV 2415
              TS ++ S   P     + +ST T   G+T L  +TV
Sbjct: 1662 VITSTEVSSSPTPAEGTSMPTSTYT--EGRTPLTSITV 1697



 Score = 80.1 bits (196), Expect = 3e-14
 Identities = 225/1031 (21%), Positives = 364/1031 (35%), Gaps = 152/1031 (14%)

Query: 1477 ERNSSETKSHLLSSSD--AEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDM 1534
            + NS  T S  +SSS   AEG       ++P++  S+     TP  S P S ++  V   
Sbjct: 832  DSNSPVTTSTEVSSSPTPAEGT------SMPTSTYSEGR---TPLTSMPVSTTL--VATS 880

Query: 1535 EIETSEVKKV-TSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVITEVTTM-- 1591
             I T     V TS+P+T+  E+  S    +   +P +      GE       T +T+M  
Sbjct: 881  AISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTS----TPGEGS-----TPLTSMPD 931

Query: 1592 --TSTVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISV 1649
              T  V++E++T+          V +STE  A S+ TT   T    STPS G +   ++ 
Sbjct: 932  STTPVVSSEARTLSATPVDTSTPVTTSTE--ATSSPTTAEGTSIPTSTPSEGTTP--LTS 987

Query: 1650 KEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTAL---- 1705
               S T+V  +   +L+TT     T +T S E S+           P  T  GT++    
Sbjct: 988  TPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASS-----------PPPTAEGTSMPTST 1036

Query: 1706 PSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGI 1765
            PS           S  ++ + +   L+        P   Y+   +       +  PT   
Sbjct: 1037 PSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTY 1096

Query: 1766 TWRYRLQTVKSLAGVSLMLRLLWAS---------------LRWDDMAAKAPPGGGTTRTE 1810
            +     +    L  V +  RL+ +S               +     A+ +P     T   
Sbjct: 1097 S-----EGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIP 1151

Query: 1811 TSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIG-----VPETPKETPTPQRKGLRSS 1865
            TS     TT +     V    + S         P+         T   +P P  +     
Sbjct: 1152 TSPPSEGTTPLASM-PVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMP 1210

Query: 1866 ALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKP 1925
               P    TP  + PV   T VA  E            V+         +        + 
Sbjct: 1211 TSTPGERSTPLTSMPVR-HTPVASSEASTLS----TSPVDTSTPVTTSAETSSSPTTAEG 1265

Query: 1926 TVIATSTTSPTSSTTSTISPAQKVMVAP-----ISGSVTTGTKMVLTTKVGS---PATVT 1977
            T + TSTTS  S+  ++I  +  ++ +P     ++  V T   +V + +V S   PA  T
Sbjct: 1266 TSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGT 1325

Query: 1978 FQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIP--SSTGTSQQTFTSFQPRTATVTI 2035
                  + +          + + V      +L   P  +ST  +  T     P T+  T 
Sbjct: 1326 SMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTS 1385

Query: 2036 RPNTSGSGGTT--SNSQVITGPQIRP-GMTVIRTPLQQSTLGKAIIRTP--------VMV 2084
             PN++ S GTT  ++  V T P +     T+  TP+  ST G               + +
Sbjct: 1386 MPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISI 1445

Query: 2085 QPGAPQQVMTQIIRGQPVST---AVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPR-- 2139
                P +  T + +  PVS    A S  +T+S+TP   +    TST+   SS+  P    
Sbjct: 1446 PTSTPSEGKTPL-KSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTA--VSSSPTPAEGT 1502

Query: 2140 ------PQQGQVKLTMAQLTQLTQGHGGNQGLT---------VVIQGQGQ--------TT 2176
                  P +G   LT   ++  T        L+         V    Q          T+
Sbjct: 1503 SIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTS 1562

Query: 2177 GQLQLIPQGVTVLPG-PGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGT 2235
             Q     +G T L   P   ++  +    T+     TP+ +     ++T  + STTA G+
Sbjct: 1563 MQTSTYSEGSTPLTSLPVSTMLVVSSEANTLST---TPIDSKTQVTASTEASSSTTAEGS 1619

Query: 2236 GE--QRQSKLSPQMQVHQDKTLP----PAQSSSVGPAEAQPQ---TAQPSAQPQPQTQPQ 2286
                   S+ SP +      T P     A + S  P ++      + + S+ P P     
Sbjct: 1620 SMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTS 1679

Query: 2287 SPAQPEVQ-----TQPEVQTQTTVSSHVPSEAQPTHAQSSKP---QVAAQSQPQSNVQGQ 2338
             P     +     T   V+T T V+S   S    T   +S P      A+S P ++    
Sbjct: 1680 MPTSTYTEGRTPLTSITVRT-TPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTS 1738

Query: 2339 SPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQ 2398
             P    S   T +  S P   +P   S+  T ++ PI      +    +   P +     
Sbjct: 1739 MPNSTPSEGTTPLT-SIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTS 1797

Query: 2399 SSTQTLSSGQT 2409
              T TLS G T
Sbjct: 1798 IPTSTLSEGMT 1808



 Score = 79.0 bits (193), Expect = 7e-14
 Identities = 220/993 (22%), Positives = 326/993 (32%), Gaps = 167/993 (16%)

Query: 1480 SSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQT-TTPSASCPESNSVNQVEDMEIET 1538
            SSE  +   +  D++     S E   ST    S+ T +TPS   P   S+          
Sbjct: 1587 SSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSI---------- 1636

Query: 1539 SEVKKVTSSPITSEEESNLSNDFIDENGLPINKNE-------------NVNGESKRKTVI 1585
                 V+++P+ S E S LS   +D N   I   E               +  ++ +T +
Sbjct: 1637 ----PVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPL 1692

Query: 1586 TEVTTMTSTVATESKTVIKVEKGDKQT-VVSSTENCAKSTVTTTTTTVTKLSTPSTGGSV 1644
            T +T  T+ VA+ + + +     D  T V +STE  A+S+ TT+  T    STPS  G+ 
Sbjct: 1693 TSITVRTTPVASSAISTLSTTPVDNSTPVTTSTE--ARSSPTTSEGTSMPNSTPSE-GTT 1749

Query: 1645 DIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSG-- 1702
             + S+   S T V ++   +L+ T     T +T S E +T         S P  T S   
Sbjct: 1750 PLTSI-PVSTTPVLSSEASTLSATPIDTSTPVTTSTE-ATSSPTTAEGTSIPTSTLSEGM 1807

Query: 1703 ---TALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSP 1759
               T+ P     V  S   ++   P D    +     +                    SP
Sbjct: 1808 TPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSS------------------SP 1849

Query: 1760 RPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETE-ITT 1818
             P  G +      +  S A  S+ +                     TT   +SET  ++T
Sbjct: 1850 TPAEGTSIATSTPSEGSTALTSIPV--------------------STTTVASSETNTLST 1889

Query: 1819 TEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQT 1878
            T  +    V  Y   S         P     +   T TP R+G      RP     P  T
Sbjct: 1890 TPAVTSTPVTTYAQVSS-------SPTTADGSSMPTSTP-REG------RPPLTSIPVST 1935

Query: 1879 GPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATS-----TT 1933
                  T VA  E+          R                     PT   +      T+
Sbjct: 1936 ------TTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTS 1989

Query: 1934 SPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATV--TFQQNKNFHQTFATW 1991
             P S+T    S A  +   P+  S    T    T    SP T   T  Q     +     
Sbjct: 1990 MPLSTTLVVSSEASTLSTTPVDTSTPATTS---TEGSSSPTTAGGTSIQTSTPSERTTPL 2046

Query: 1992 VKQGQSNSGVVQVQQKVLGIIPSSTGT----SQQTFTSFQPRTATVTIRPNTSGSGGTTS 2047
                 S + VV  +   L   P  + T    S +  +S     +++TI   + GS   TS
Sbjct: 2047 AGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTS 2106

Query: 2048 NSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQP----GAPQQVMTQIIR----- 2098
                 T        T+  TP+  ++    I  T V   P    G   Q  T   R     
Sbjct: 2107 IPLSTTPVASPEASTLSTTPVDSNS--PVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLT 2164

Query: 2099 GQPVSTAV---SAPNTVSSTPGQKSL-----TSATSTSNIQSSASQP-PRPQQGQVKLTM 2149
              PVST V   SA +T+S+TP   S      T A S+       S P   P +G    T 
Sbjct: 2165 SMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTS 2224

Query: 2150 ------------AQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLM 2197
                        A     T         T        TT +   IP   + L      L 
Sbjct: 2225 MPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIP--TSTLSEGTTPLT 2282

Query: 2198 QAAMPNGTVQRFLFTPLATTATTAST--TTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTL 2255
               + +  V     + L+TT   ++T  TT+T +++   T E      S   + +   T 
Sbjct: 2283 SIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTR 2342

Query: 2256 PPAQSSSVGPAEAQPQTAQPSAQPQP-QTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQ 2314
             P  ++ V   E    +  P+    P  T  Q+ + P       + T T      P  + 
Sbjct: 2343 MPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSV 2402

Query: 2315 PTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQP 2374
            P    S+ P V++++   S               T +  STP   S    S   T     
Sbjct: 2403 PV---STMPVVSSEASTHST--------------TPVDTSTPVTTSTEASSSPTTAEGTS 2445

Query: 2375 IPIQPHTSLQIPSQGQPQS-QPQVQSSTQTLSS 2406
            IP  P +    P    P S  P V S   TLS+
Sbjct: 2446 IPTSPPSEGTTPLASMPVSTTPVVSSEAGTLST 2478



 Score = 73.2 bits (178), Expect = 4e-12
 Identities = 246/1205 (20%), Positives = 424/1205 (35%), Gaps = 141/1205 (11%)

Query: 1283 SESNSTLENSSDTVSIQDSSEEDM------------IVQNSNESIS-------------- 1316
            +ES +T E++SD+ ++  SS ED             +   S ESIS              
Sbjct: 113  TESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSF 172

Query: 1317 EQFRTREQDVEVLEPLKCELVSGESTGNCEDRLPVKGTEANGKKP------SQQKKLEER 1370
            E + +    V++  PL     +  S    E     K T + G  P      S  K     
Sbjct: 173  EAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSE 232

Query: 1371 PVNKCSDQIKLKN-TTDKKNNENRESEKKGQRTSTFQINGKDNKPKIYLKGECLKEISES 1429
             +   +  +++    T      +  +  +G   S    +G             L   SE+
Sbjct: 233  AITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEA 292

Query: 1430 RVVSGNVEPKVNNINKIIPENDIKSLTVKESAIRP---FINGDVIMEDFNERN----SSE 1482
              +S    P   NI  I       S T  E    P   +  G   +           +SE
Sbjct: 293  STLS--TTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSE 350

Query: 1483 TKSHLLSSSDAEGNYRDSLE--TLPSTKESDSTQTTTPS-ASCPESNSVNQVEDMEIETS 1539
              +  ++  D       S E  +LP+T E+ S  T+T S  S P +N    V  + + +S
Sbjct: 351  MSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNM--PVSTILVASS 408

Query: 1540 EVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVITEVTTMTSTVATES 1599
            E    ++ P+ S+     +++         + +   +  S+  T +T +   T+ VA+  
Sbjct: 409  EASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSE 468

Query: 1600 KTVIKVEKGDKQTVVSSTENCAKSTVTTT-----TTTVTKLSTPSTGGSVDIISVKEQSK 1654
             + +     D +T V+++   + S  T       T+T ++ STP T  SV  + V     
Sbjct: 469  ASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEA 528

Query: 1655 TVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTK 1714
            + ++TT  D+ T     + TS   S   +T +   +   +  + +   T +P   + V  
Sbjct: 529  STLSTTPVDTSTP----VTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVS 584

Query: 1715 SSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTV 1774
            S   +    P D    +       E    +  A+         +  PT   T+  R  T+
Sbjct: 585  SEASTTSTTPADSNTFVTTSS---EASSSSTTAEG--------TSMPTS--TYSERGTTI 631

Query: 1775 KSLAGVSLMLRLLWAS-LRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIR 1833
             S++  + ++    AS L    + +  P    T  T +S T   T+        G   + 
Sbjct: 632  TSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLT 691

Query: 1834 SEYCIRKIICPIG---VPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEE 1890
            S      ++       +  TP +T TP      +S+     P T    G  +  +  +E 
Sbjct: 692  SMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASS----SPTTAD--GASMPTSTPSEG 745

Query: 1891 ELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVM 1950
               L  +      V K    + E            T I TST +  S TT+        +
Sbjct: 746  STPLTSMP-----VSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTT--EGTSMPI 798

Query: 1951 VAPISGSVTTGTKMVLTTKVGSPATVTFQQ---NKNFHQTFATWVKQGQSNSGVVQVQQK 2007
              P  GS    +  V  T V SP   T      + N   T +T V    + +    +   
Sbjct: 799  STPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSM--- 855

Query: 2008 VLGIIPSSTGTSQQTFTSFQPRTATV--TIRPNTSGSGGTTSNSQVITGPQIRPGMTVIR 2065
                 P+ST +  +T  +  P + T+  T   +T  +    +++ V    + R   T   
Sbjct: 856  -----PTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSE 910

Query: 2066 -TPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSA 2124
             T +  ST G+    TP+   P +   V++   R       +SA    +STP   S  + 
Sbjct: 911  GTSMPTSTPGEG--STPLTSMPDSTTPVVSSEAR------TLSATPVDTSTPVTTSTEAT 962

Query: 2125 TSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQ 2184
            +S +  + ++     P +G   LT   ++            T+V   +  T   L   P 
Sbjct: 963  SSPTTAEGTSIPTSTPSEGTTPLTSTPVSH-----------TLVANSEAST---LSTTPV 1008

Query: 2185 GVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTT---VSTTAAGTGEQRQS 2241
                   P     +A+ P  T +    T + T+  +  +T  T   VSTT   + E    
Sbjct: 1009 DSNT---PLTTSTEASSPPPTAEG---TSMPTSTPSEGSTPLTRMPVSTTMVASSETSTL 1062

Query: 2242 KLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQT 2301
              +P        T   A SSS         T+  S    P T      +  V ++    +
Sbjct: 1063 STTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLS 1122

Query: 2302 QTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQS-NVQGQSPVRVQSPSQTRIRPSTPSQLS 2360
             T V + +P     T A SS       S P S   +G +P+     S T +  S  + LS
Sbjct: 1123 TTPVDTSIPVTTS-TEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLS 1181

Query: 2361 P---GQQSQVQTTT--SQPIPIQPHTSLQIPSQGQ---PQSQPQVQSSTQTLSSGQTLNQ 2412
                  ++QV T+T  S P P    TS+   + G+   P +   V+ +    S   TL+ 
Sbjct: 1182 TTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLST 1241

Query: 2413 VTVSS 2417
              V +
Sbjct: 1242 SPVDT 1246



 Score = 73.2 bits (178), Expect = 4e-12
 Identities = 207/990 (20%), Positives = 325/990 (32%), Gaps = 138/990 (13%)

Query: 1477 ERNSSETK--SHLLSSSDAEGN---YRDSLETLPSTKESDSTQTTTPS-------ASCPE 1524
            E +SS T   S +  S+ +EG+       + T P      ST +TTP         S   
Sbjct: 1609 EASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEV 1668

Query: 1525 SNSVNQVEDMEIETSEVKK---------VTSSPITSEEESNLSNDFIDENGLPINKNENV 1575
            S+S    E   + TS   +         V ++P+ S   S LS   +D N  P+  +   
Sbjct: 1669 SSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVD-NSTPVTTST-- 1725

Query: 1576 NGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENCAK------STVTTTT 1629
              E++     +E T+M ++  +E  T +         V+SS  +         ST  TT+
Sbjct: 1726 --EARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTS 1783

Query: 1630 TTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTG--GTLVTSMTVSKEYSTRDK 1687
            T  T   T + G S+   ++ E    + +T V+ +L       TL T+   S        
Sbjct: 1784 TEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTST 1843

Query: 1688 VKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNY-- 1745
                  +  + T   T+ PS       S   S   + + +   L+    +   P   Y  
Sbjct: 1844 AVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQ 1903

Query: 1746 -NAKPAL---DIWPYPSPR----PTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMA 1797
             ++ P        P  +PR    P   I           +  +S  L      +     A
Sbjct: 1904 VSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQA 1963

Query: 1798 AKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTP 1857
            + +P     T   T      +T +          + SE           +  TP +T TP
Sbjct: 1964 SSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEAST--------LSTTPVDTSTP 2015

Query: 1858 QRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAK 1917
                   S+       +P   G   I+T    E             V      + E    
Sbjct: 2016 ATTSTEGSS-------SPTTAGGTSIQTSTPSERTT----PLAGMPVSTTLVVSSEGNTL 2064

Query: 1918 KRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVT 1977
                    T +  ST + +S+T    S     + AP  GS    +  + TT V SP   T
Sbjct: 2065 STTPVDSKTQVTNSTEASSSATAEGSS---MTISAPSEGSPLLTSIPLSTTPVASPEAST 2121

Query: 1978 FQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRP 2037
                               SNS V+   +     IP+  GTS QT T    RT   ++  
Sbjct: 2122 LSTTPV------------DSNSPVITSTEVSSSPIPTE-GTSMQTSTYSDRRTPLTSMPV 2168

Query: 2038 NTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTP--VMVQPGAPQQVMTQ 2095
            +T     T   S  I+     P  T   TP+  ST  ++   T     +    P +  T 
Sbjct: 2169 ST-----TVVASSAISTLSTTPVDT--STPVTNSTEARSSPTTSEGTSMPTSTPSEGSTP 2221

Query: 2096 IIRGQPVST---AVSAPNTVSSTPGQKSL-----TSATSTSNIQSSASQPPRP-QQGQVK 2146
                 PVST     S  +T+S+TP   S      T ATS+       S P     +G   
Sbjct: 2222 FT-SMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTP 2280

Query: 2147 LTMAQL--TQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNG 2204
            LT   +  T +          T V      TT          T    P       +MP  
Sbjct: 2281 LTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTS---------TEASSPPPTAEGTSMPTS 2331

Query: 2205 TVQRFLFTPLA----TTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQS 2260
            T      TPL     +T   AS  T+T+STT A T        +P     Q  + P    
Sbjct: 2332 TSSEGN-TPLTRMPVSTTMVASFETSTLSTTPADTS-------TPVTTYSQAGSSPTTAD 2383

Query: 2261 SSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQS 2320
             +  P     + + P       T P   ++    +   V T T V++   + + PT A+ 
Sbjct: 2384 DTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEG 2443

Query: 2321 SKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPH 2380
            +    +  S      +G +P+            S P   +P   S+  T ++ P+     
Sbjct: 2444 TSIPTSPPS------EGTTPL-----------ASMPVSTTPVVSSEAGTLSTTPVDTSTP 2486

Query: 2381 TSLQIPSQGQPQSQPQVQSSTQTLSSGQTL 2410
             +    +   P +   +     T S G TL
Sbjct: 2487 MTTSTEASSSPTTAEDIVVPISTASEGSTL 2516



 Score = 73.2 bits (178), Expect = 4e-12
 Identities = 198/998 (19%), Positives = 339/998 (33%), Gaps = 186/998 (18%)

Query: 1500 SLETLPSTKESDSTQTTTPSASCPESNSV----NQVEDMEIET-SEVKKVTSSPITSEEE 1554
            ++ + P+  E  S  T+TPS       S+      V   E  T S    VTS+P+T+  +
Sbjct: 1844 AVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQ 1903

Query: 1555 SNLSNDFIDENGLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVV 1614
             + S    D + +P +         + +  +T +   T+TVA+     +     D +T V
Sbjct: 1904 VSSSPTTADGSSMPTSTPR------EGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPV 1957

Query: 1615 SSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVT 1674
            ++    + S    TT   T + TP+       ++    S T+V ++   +L+TT     T
Sbjct: 1958 TTYSQASSSP---TTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTST 2014

Query: 1675 SMTVSKEYS----TRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKK 1730
              T S E S    T     +   +  ++T     +P     V  S   ++   P D   +
Sbjct: 2015 PATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQ 2074

Query: 1731 LARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWAS 1790
            +                          S   +   T      T+ + +  S +L  +   
Sbjct: 2075 VTN------------------------STEASSSATAEGSSMTISAPSEGSPLLTSI--P 2108

Query: 1791 LRWDDMAAKAPPGGGTTRTETSETEITTTEII------------------KRRDVGPYGI 1832
            L    +A+       TT  +++   IT+TE+                   +R  +    +
Sbjct: 2109 LSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPV 2168

Query: 1833 RSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALR----------PKRPETPKQTGPVI 1882
             +       I  +        TP       RSS             P    TP  + PV 
Sbjct: 2169 STTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVS 2228

Query: 1883 IETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTST 1942
                V  E   L      A  V+         +A       + T I TST S  ++  ++
Sbjct: 2229 TMPVVTSEASTL-----SATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTS 2283

Query: 1943 ISPAQKVMVAPISGS------VTTGTKMVLTTKVGSP---ATVTFQQNKNFHQTFATWVK 1993
            I P    +VA    S      V + T    +T+  SP   A  T        +      +
Sbjct: 2284 I-PVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTR 2342

Query: 1994 QGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSF--QPRTATVTIRPNTSGSGGTT--SNS 2049
               S + V   +   L   P+ T T   T++     P TA  T  P ++ S G+T  ++ 
Sbjct: 2343 MPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSV 2402

Query: 2050 QVITGPQIRP-GMTVIRTPLQQST---LGKAIIRTPVMVQ----PGAPQQVMTQIIRGQP 2101
             V T P +     T   TP+  ST          +P   +    P +P    T  +   P
Sbjct: 2403 PVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMP 2462

Query: 2102 VSTAV---SAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQG 2158
            VST     S   T+S+TP   S    TST     ++S P   +   V ++ A        
Sbjct: 2463 VSTTPVVSSEAGTLSTTPVDTSTPMTTSTE----ASSSPTTAEDIVVPISTA-------- 2510

Query: 2159 HGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTA 2218
               ++G T+           L  IP   T +  P    +     +        T ++++A
Sbjct: 2511 ---SEGSTL-----------LTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSA 2556

Query: 2219 TTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQ 2278
            T+A  T+   ST + G+                             P  + P + +P A 
Sbjct: 2557 TSAEGTSMPTSTYSEGST----------------------------PLRSMPVSTKPLAS 2588

Query: 2279 PQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQ-------- 2330
             +  T   +P    V T   V T T  SS       PT A+ +   ++  S+        
Sbjct: 2589 SEASTLSTTP----VDTSIPVTTSTETSS------SPTTAKDTSMPISTPSEVSTSLTSI 2638

Query: 2331 -----PQSNVQGQSPVRVQSPSQTRIRPSTPSQLSP--GQQSQVQTTT----SQPIP-IQ 2378
                 P ++ +  +       ++T +  ST +  SP   + S + T+T    S P+  I 
Sbjct: 2639 LVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNIL 2698

Query: 2379 PHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVS 2416
              T+L   S+    S   V +ST   +S +  +  T +
Sbjct: 2699 VSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTA 2736



 Score = 70.9 bits (172), Expect = 2e-11
 Identities = 273/1368 (19%), Positives = 456/1368 (33%), Gaps = 206/1368 (15%)

Query: 1180 PKQNSIENDIEEKVSDLASRGQEPSKSKT-------------------------KGNDF- 1213
            P+  SIE+ +      ++S    P++S+T                         +G D  
Sbjct: 89   PEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVP 148

Query: 1214 --------------FIDDSKLASADDIGTLICKNKKPLIQEESDTIVSSSKSALHSSVPK 1259
                          F+  + L S +   +L  K         S    SS  +   +++PK
Sbjct: 149  MSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPK 208

Query: 1260 STNDRDATPLSRAMDFEGKLGCDSESNSTLENSSD-----TVSIQDSSE----EDMIVQN 1310
            STN   +TPL+ +M         SE+ + L    +     T+S Q SS     E   + N
Sbjct: 209  STNSEGSTPLT-SMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSN 267

Query: 1311 SNESISEQFRTREQDVEVLEPLKCELVSGESTGNCEDRLPVKGTEAN------------- 1357
            S  S      TR   + V+  +  E  +  +T    +   +  TEA+             
Sbjct: 268  SAPSGGSTPLTR-MPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPT 326

Query: 1358 -----GKKPSQQKKLEERPVNKCS---------DQIKLKNTTDKKNNENRESEKKGQRTS 1403
                 G  P         PV             D   L  T+ + ++    +E     TS
Sbjct: 327  STYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTS 386

Query: 1404 TFQINGKDNKPKIYLKGECLKEISESRVVSGNVEPKVNNINKIIPENDIKSLTVKESAIR 1463
            T     + + P        L  +  S ++  + E   +  + I  ++     T  E++  
Sbjct: 387  TL---SEGSTP--------LTNMPVSTILVASSE--ASTTSTIPVDSKTFVTTASEASSS 433

Query: 1464 PFINGDV-IMEDFNERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASC 1522
            P    D  I        S+   S  +S++    +   +L T P   ++  T +T  S+S 
Sbjct: 434  PTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSP 493

Query: 1523 P--ESNSV--------------NQVEDMEIETSEVKKVTSSPITSEEESNLSNDFIDENG 1566
            P  E NS+                V  M + +SE   ++++P+ +      S++    + 
Sbjct: 494  PTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSST 553

Query: 1567 LPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENCAKSTVT 1626
             P   +   +  S+  T +T +   T  V +   +       D  T V+++   + S+ T
Sbjct: 554  TPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTT 613

Query: 1627 T-----TTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLT-TTGGTLVTSMTVSK 1680
                   T+T ++  T  T  SV    V     + ++TT  DS T  T  T  TS + + 
Sbjct: 614  AEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTA 673

Query: 1681 EYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREV 1740
            E ++       + S P      T++P     V  S   ++   P D    +         
Sbjct: 674  EGTSMPTSTYTEGSTPL-----TSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSS 728

Query: 1741 PYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKA 1800
            P          D    P+  P+ G T    +   K+L   S    L    L   D +   
Sbjct: 729  P-------TTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPL---DTSTHI 778

Query: 1801 PPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPE--TPKETPTPQ 1858
                 TT TE S +  TT            G      I   I P+  PE  T   TP   
Sbjct: 779  -----TTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDS 833

Query: 1859 RKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKK 1918
               + +S      P TP +   +   T+ +E    L  +      V      A+   +  
Sbjct: 834  NSPVTTSTEVSSSP-TPAEGTSMPTSTY-SEGRTPLTSMPVSTTLV---ATSAISTLSTT 888

Query: 1919 RLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTF 1978
             ++   P   +T   S  +++  T  P       P  GS    +    TT V S    T 
Sbjct: 889  PVDTSTPVTNSTEARSSPTTSEGTSMPTS----TPGEGSTPLTSMPDSTTPVVSSEARTL 944

Query: 1979 QQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSST---GTSQQTFTSF------QPR 2029
                    T  T   +  S+    +        IP+ST   GT+  T T           
Sbjct: 945  SATPVDTSTPVTTSTEATSSPTTAEGTS-----IPTSTPSEGTTPLTSTPVSHTLVANSE 999

Query: 2030 TATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAP 2089
             +T++  P  S +  TTS       P          TP + ST    + R PV     A 
Sbjct: 1000 ASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGST---PLTRMPVSTTMVAS 1056

Query: 2090 QQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTM 2149
             +  T        ST V+  +  SS+      TS  +++  + S      P   ++ ++ 
Sbjct: 1057 SETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSS 1116

Query: 2150 AQLTQLTQGHGGNQGLTVVIQGQGQ-TTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQR 2208
               T  T     +  +T   +     TT +   IP   T  P  G   + A+MP  T   
Sbjct: 1117 EASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIP---TSPPSEGTTPL-ASMPVSTT-- 1170

Query: 2209 FLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEA 2268
                 +++ A T STT     T  A + E   S   P  +V    T  P + S+  P  +
Sbjct: 1171 ---LVVSSEANTLSTTPVDSKTQVATSTE--ASSPPPTAEVTSMPTSTPGERST--PLTS 1223

Query: 2269 QPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQ 2328
             P    P A  +  T   SP          V T T V++   + + PT A+ +    +  
Sbjct: 1224 MPVRHTPVASSEASTLSTSP----------VDTSTPVTTSAETSSSPTTAEGTSLPTSTT 1273

Query: 2329 SQ-----------------PQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTT 2371
            S+                 P+++    +PV  + P  T    S+    + G      T +
Sbjct: 1274 SEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYS 1333

Query: 2372 SQPIP---IQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVS 2416
                P   I  +T+L   S     S   V +ST   +S +  +  T S
Sbjct: 1334 EGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTS 1381



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 181/869 (20%), Positives = 283/869 (32%), Gaps = 146/869 (16%)

Query: 1500 SLETLPSTKESDSTQTTTP-------SASCPESNSVNQVEDMEIETSEVKK--------- 1543
            S  T P      ST +TTP       + S   S S    E   I TS   +         
Sbjct: 3346 SFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMP 3405

Query: 1544 VTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVI 1603
            V+++P+ S E + LS   +D N L     E     +     I E T++ ++  +E  T +
Sbjct: 3406 VSTTPVVSSEVNTLSTTPVDSNTLVTTSTE-----ASSSPTIAEGTSLPTSTTSEGSTPL 3460

Query: 1604 KVEKGDKQTVVSSTENCAKST-------VTT--------TTTTVTKLSTPSTGGSVDIIS 1648
             +       V SS  +   +T       VTT        TT  VT + T + G     ++
Sbjct: 3461 SIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLT 3520

Query: 1649 VKEQSKTVVTTTVTDSLTTT---GGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTAL 1705
                S T V ++   +L+TT     T VTS + +       +V  M+ S P +  S    
Sbjct: 3521 NMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTT 3580

Query: 1706 PSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGI 1765
                     SS+ S    P+ D          R  P        +    P P    T  +
Sbjct: 3581 MLLSSTYVTSSEASTPSTPSVD----------RSTPVTTSTQSNST---PTPPEVITLPM 3627

Query: 1766 TWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRR 1825
            +    + T  ++  VS        S+   +    +     T+    + T+++++ +    
Sbjct: 3628 STPSEVSTPLTIMPVST------TSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEG 3681

Query: 1826 DVGPYGIRSEYCIRKIICPIGV-------------PETPKETP-TPQRKGLRSSALRPKR 1871
               P    SE        P+               P     TP T   + + SSA     
Sbjct: 3682 TTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDST 3741

Query: 1872 PETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQ--QKPTVIA 1929
              T   + P+ I T      +    +  F E             +     +    PT + 
Sbjct: 3742 --TMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLE 3799

Query: 1930 TSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFA 1989
             +TT P S+T+   +    V+++PIS  ++      L+T  G  +T              
Sbjct: 3800 GTTTMPMSTTSERSTLLTTVLISPIS-VMSPSEASTLSTPPGDTST-------------- 3844

Query: 1990 TWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNS 2049
                                   P  T T   +F S      T+ I   +  S   T+  
Sbjct: 3845 -----------------------PLLTSTKAGSF-SIPAEVTTIRISITSERSTPLTTLL 3880

Query: 2050 QVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVS-A 2108
               T P   PG ++  TP     L  +   TP       P           PV+T +S +
Sbjct: 3881 VSTTLPTSFPGASIASTP----PLDTSTTFTPSTDTASTPT---------IPVATTISVS 3927

Query: 2109 PNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVV 2168
              T  STPG      +T    + SS +       G V   +   T+L      +   T  
Sbjct: 3928 VITEGSTPGTTIFIPSTP---VTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTS 3984

Query: 2169 IQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTV 2228
                 + T      P   T  P     +  A     T  R   T  +T + T++  T+T 
Sbjct: 3985 FSTTKEFT-----TPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTS 4039

Query: 2229 STTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSA------QPQPQ 2282
             TT   T     S+ S         T PPA SS+     A   T  P A      + +P 
Sbjct: 4040 VTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPS 4099

Query: 2283 TQPQSPAQPEVQTQPEVQTQTTVSSHVPS 2311
            T+  S   P V T   V T TT+ S+  S
Sbjct: 4100 TRTTS--FPTV-TTTAVPTNTTIKSNPTS 4125



 Score = 64.7 bits (156), Expect = 1e-09
 Identities = 134/581 (23%), Positives = 217/581 (37%), Gaps = 90/581 (15%)

Query: 1926 TVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFH 1985
            T +  STT  TSS  ST+S    V   P    VTT T+ + ++      T++        
Sbjct: 3697 TTMPVSTTRVTSSEGSTLSTPSVVTSTP----VTTSTEAISSSATLDSTTMSVSMPMEI- 3751

Query: 1986 QTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGT 2045
             T  T +    S + V +  +     IPS   TS    T+ +  ++  T+   T+    T
Sbjct: 3752 STLGTTILV--STTPVTRFPESSTPSIPS-VYTSMSMTTASEGSSSPTTLEGTTTMPMST 3808

Query: 2046 TSN-SQVITGPQIRPGMTVIRTPLQQSTLGK--AIIRTPVMVQPGA-----PQQVMTQII 2097
            TS  S ++T   I P    + +P + STL        TP++    A     P +V T  I
Sbjct: 3809 TSERSTLLTTVLISP--ISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRI 3866

Query: 2098 -----RGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQL 2152
                 R  P++T + +    +S PG     S  ST  + +S +  P              
Sbjct: 3867 SITSERSTPLTTLLVSTTLPTSFPG----ASIASTPPLDTSTTFTPSTDTASTPTIPVAT 3922

Query: 2153 TQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFT 2212
            T           ++V +  +G T G    IP   T +      +  A     +      T
Sbjct: 3923 T-----------ISVSVITEGSTPGTTIFIPS--TPVTSSTADVFPATTGAVSTPVITST 3969

Query: 2213 PLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVG---PAEAQ 2269
             L T +T++S+TTT+ STT   T     +  +P   V         +++S G    A   
Sbjct: 3970 ELNTPSTSSSSTTTSFSTTKEFT-TPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTL 4028

Query: 2270 PQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSH-VPSEAQPTHAQSSKPQVAAQ 2328
              T+ P       T+P +P+        E    +T++SH +P    P H  SS P   + 
Sbjct: 4029 SATSTPHTSTSVTTRPVTPSS-------ESSRPSTITSHTIPPTFPPAH--SSTPPTTSA 4079

Query: 2329 SQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQ 2388
            S    N +  + +       TR +PST +   P       TTT+ P      T+  I S 
Sbjct: 4080 SSTTVNPEAVTTM------TTRTKPSTRTTSFP-----TVTTTAVP------TNTTIKS- 4121

Query: 2389 GQPQSQPQVQSSTQTLSSG-QTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQ 2447
              P S P V  +T     G Q       +  +   L+ Q P                  +
Sbjct: 4122 -NPTSTPTVPRTTTCFGDGCQNTASRCKNGGTWDGLKCQCPN-------------LYYGE 4167

Query: 2448 IQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQN 2488
            +  +VV+ I     G P+ I  Q+ + +  +S   T +++N
Sbjct: 4168 LCEEVVSSIDI---GPPETISAQMELTVTVTSVKFTEELKN 4205



 Score = 55.5 bits (132), Expect = 8e-07
 Identities = 121/600 (20%), Positives = 196/600 (32%), Gaps = 97/600 (16%)

Query: 1926 TVIATSTTSPTSSTTSTISPAQKVMVAPI------SGSVTT--GTKMVLTT--------- 1968
            T I  STT+  SS  +++S    V   P+      S S TT  GT M  +T         
Sbjct: 1517 TSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLT 1576

Query: 1969 --KVGSPATVTFQQN--------KNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGT 2018
               V +   V+ + N             T +T      +  G            P  T  
Sbjct: 1577 SLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSI 1636

Query: 2019 SQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPG-------MTVIRTPLQQS 2071
               T     P  +T++  P  S S   TS ++V + P    G        T  RTPL   
Sbjct: 1637 PVSTTPVASPEASTLSTTPVDSNSPVITS-TEVSSSPTPAEGTSMPTSTYTEGRTPLTSI 1695

Query: 2072 TLGKAIIRTPVM-------VQPGAPQQVMTQIIRGQPVSTAVSAPNT------------- 2111
            T+    + +  +       V    P    T+       S   S PN+             
Sbjct: 1696 TVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIP 1755

Query: 2112 VSSTPGQKSLTSATSTSNIQSS--------ASQPPRPQQGQVKLTMAQLTQLTQGHGGNQ 2163
            VS+TP   S  S  S + I +S        A+  P   +G    T      +T       
Sbjct: 1756 VSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPV 1815

Query: 2164 GLTVVIQGQGQT-------TGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLAT 2216
              T+V   +  T       +    +    V+  P P +    A          L +   +
Sbjct: 1816 SHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVS 1875

Query: 2217 TATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPS 2276
            T T AS+ T T+STT A T        +P     Q  + P     S  P     +   P 
Sbjct: 1876 TTTVASSETNTLSTTPAVTS-------TPVTTYAQVSSSPTTADGSSMPTSTPREGRPPL 1928

Query: 2277 AQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQ------ 2330
                  T   + ++    +     T+T V+++  + + PT A  +     A S+      
Sbjct: 1929 TSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLT 1988

Query: 2331 -----------PQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPI-- 2377
                        +++    +PV   +P+ T    S+    + G   Q  T + +  P+  
Sbjct: 1989 SMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAG 2048

Query: 2378 -QPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVP 2436
                T+L + S+G   S   V S TQ  +S +  +  T    S       +  P + ++P
Sbjct: 2049 MPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIP 2108



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 93/495 (18%), Positives = 171/495 (34%), Gaps = 57/495 (11%)

Query: 1242 SDTIVSSSKSALHSSVPKSTNDRDATPLSRAMDFEGKLGCDSE----------SNSTLEN 1291
            S    SS  +A  +S+P ST     TPL+ ++     L  +SE          SN+    
Sbjct: 2254 STEATSSPTTAEGTSIPTSTLSEGTTPLT-SIPVSHTLVANSEVSTLSTTPVDSNTPFTT 2312

Query: 1292 SSDTVSIQDSSE-EDMIVQNSNE------------SISEQFRT---REQDVEVLEPLKCE 1335
            S++  S   ++E   M    S+E            ++   F T        +   P+   
Sbjct: 2313 STEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTY 2372

Query: 1336 LVSGESTGNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNNENRES 1395
              +G S    +D      T + G  P     +   PV             D        +
Sbjct: 2373 SQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTST 2432

Query: 1396 EKKGQRTSTFQINGKDNKPKIYLKGECLKEISESRVVSGNVEPKVNNINKIIPENDIKSL 1455
            E     T+    +   + P           +S + VVS     +   ++    +      
Sbjct: 2433 EASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSS----EAGTLSTTPVDTSTPMT 2488

Query: 1456 TVKESAIRPFINGDVIMEDFNERNSSETKSHL-LSSSDAEGNYRDSLETLPSTKESDSTQ 1514
            T  E++  P    D+++        S   + + +S++        +L T P    S    
Sbjct: 2489 TSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVT 2548

Query: 1515 TTTPSASCPESNSVNQVEDMEIETSEVKK---VTSSPITSEEESNLSNDFIDENGLPINK 1571
            +T  S+S   +   +       E S   +   V++ P+ S E S LS   +D   +P+  
Sbjct: 2549 STEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVD-TSIPVTT 2607

Query: 1572 NEN--------------VNGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSST 1617
            +                ++  S+  T +T +   T  VA+   + +     D +T+V+++
Sbjct: 2608 STETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTS 2667

Query: 1618 ENCAKSTVTT-----TTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLT--TTGG 1670
               + S  T       T+T  + STP T   V    +     + ++TT  D+ T  TT  
Sbjct: 2668 TGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSA 2727

Query: 1671 TLVTSMTVSKEYSTR 1685
               +S T ++  S R
Sbjct: 2728 EASSSPTTAEGTSMR 2742



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 43/192 (22%), Positives = 72/192 (37%), Gaps = 21/192 (10%)

Query: 1494 EGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEE 1553
            EG+   +   +PST  + ST    P+ +   S  V    ++   ++     T+S  T++E
Sbjct: 3931 EGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKE 3990

Query: 1554 ESNLSNDFIDENGLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTV 1613
             +  +         P+         S  +T     TT  ST++                 
Sbjct: 3991 FTTPAMT----TAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSA---------------- 4030

Query: 1614 VSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLV 1673
             +ST + + S  T   T  ++ S PST  S  I      + +    T + S TT     V
Sbjct: 4031 -TSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAV 4089

Query: 1674 TSMTVSKEYSTR 1685
            T+MT   + STR
Sbjct: 4090 TTMTTRTKPSTR 4101


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 121/488 (24%), Positives = 173/488 (35%), Gaps = 39/488 (7%)

Query: 1921 EQQKPTVIATSTT---SPTSSTTSTISPAQKVMVAPISGSVT-TGTKMVLTTKVGSPATV 1976
            E   PT I T+TT   +PT ++T + +P        ++ + T TGT+   TT + +  TV
Sbjct: 1309 ENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 1368

Query: 1977 TFQQNKNFHQT-------FATWVKQGQSNSGVVQVQQKVLG----IIPSSTGTSQQTFTS 2025
            T        QT         T V    + +G        +     + P+ T T  QT T+
Sbjct: 1369 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTT 1428

Query: 2026 FQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQ 2085
              P T T T+ P  + +G        IT       +T   TP    T     I T   V 
Sbjct: 1429 -TPITTTTTVTPTPTPTGTQAPTPTAITTTST---VTPTPTPTGTQTPTTTPITTTTTVT 1484

Query: 2086 PGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQV 2145
            P  P    TQ     P  TA++   TV+ TP      + TST    ++   P     G  
Sbjct: 1485 P-TPTPTGTQT----PTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQ 1539

Query: 2146 KLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPG----QQLMQAAM 2201
              T   ++  T        +T      G  T     I    TV P P     Q      +
Sbjct: 1540 TPTPTPISTTTT-------VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLI 1592

Query: 2202 PNGTVQRFLFTPLATTATTAS--TTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQ 2259
               T      TP +T +TT +  TTTTTV+ T   TG Q  + +          T  P  
Sbjct: 1593 TTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTT 1652

Query: 2260 SSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQ 2319
             S+  P               P  +  +P      + P  ++ T +S+  P+    + A 
Sbjct: 1653 GSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAP 1712

Query: 2320 SSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQP 2379
             S P  A  +    +     P    SP  T  R +T    S    S VQTTT+      P
Sbjct: 1713 PSTP-TAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTP 1771

Query: 2380 HTSLQIPS 2387
             T L  PS
Sbjct: 1772 -TPLSTPS 1778



 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 133/544 (24%), Positives = 187/544 (34%), Gaps = 79/544 (14%)

Query: 1923 QKPTVIATSTTSPTS---STTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQ 1979
            Q  T+  T+T +PT    +TT+T++P       P S   TT T +  TT V    T T  
Sbjct: 1299 QPTTMTTTTTENPTPTPITTTTTVTPTP----TPTSTQSTTPTPITTTTTVTPTPTPTGT 1354

Query: 1980 QNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNT 2039
            Q         T                    + P+ T T  QT T+  P T T T+ P  
Sbjct: 1355 QTPTTTPITTTTT------------------VTPTPTPTGTQTPTT-TPITTTTTVTPTP 1395

Query: 2040 SGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRG 2099
            + +G  T  S  IT       +T   TP    T     I T   V P  P    TQ    
Sbjct: 1396 TPTGTQTPTSTPIT---TTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQ---- 1447

Query: 2100 QPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQP-PRPQQGQVKLTMAQLTQLTQG 2158
             P  TA++  +TV+ TP      + T+T    ++   P P P   Q     A  T  T  
Sbjct: 1448 APTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTT-- 1505

Query: 2159 HGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTP----- 2213
                  +T      G  T     I    TV P P     Q   P         TP     
Sbjct: 1506 ------VTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPT 1559

Query: 2214 -LATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQT 2272
               T  TT  TTTTTV+ T   TG Q  +     + +    T+ P  +    P   +  T
Sbjct: 1560 GTQTPTTTPITTTTTVTPTPTPTGTQTPT----TVLITTTTTMTPTPT----PTSTKSTT 1611

Query: 2273 AQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTV----SSHVPSEAQPTHAQ--------S 2320
              P       T   +P   +  T   + T TTV    +    S   PTH          +
Sbjct: 1612 VTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTT 1671

Query: 2321 SKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTP-SQLSPGQQSQVQTTTSQPIPIQP 2379
            S P     S PQ++    SP+   +   + + P+   +  +P       TTTS    + P
Sbjct: 1672 SNPP-PESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSP 1730

Query: 2380 HTSLQIPSQGQP--------QSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQ 2431
              S      G P         S P   +   T +S  T     +S+PS  +    +P P 
Sbjct: 1731 PPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPS 1790

Query: 2432 VIAV 2435
             + +
Sbjct: 1791 SVLI 1794



 Score = 75.5 bits (184), Expect = 7e-13
 Identities = 121/541 (22%), Positives = 184/541 (34%), Gaps = 75/541 (13%)

Query: 1925 PTVIATSTTSPTSSTTSTISPAQKVMVA---------PISGSVTTGTKMVLTTKVGSPAT 1975
            PT   T+TT+ T ++++ +S   K+            P SGS   G +       G+P  
Sbjct: 1178 PTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGS-DDGDRETFDGVCGAPED 1236

Query: 1976 VTFQQNKNFHQTFATWVKQGQSNSGVVQV---------QQKVLGIIPSSTGTSQQTFTS- 2025
            +  +  K+ H +     + GQ    V  V          QK  G+IP +   + +     
Sbjct: 1237 IECRSVKDPHLSLE---QLGQKVQLVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQC 1293

Query: 2026 ----FQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTP 2081
                 QP T T T   N + +  TT+ +           +T   TP    +     I T 
Sbjct: 1294 CECVTQPTTMTTTTTENPTPTPITTTTT-----------VTPTPTPTSTQSTTPTPITTT 1342

Query: 2082 VMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQ 2141
              V P  P    TQ     P +T ++   TV+ TP      + T+T    ++   P    
Sbjct: 1343 TTVTP-TPTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 1397

Query: 2142 QGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAM 2201
             G    T   +T  T        +T      G  T     I    TV P P     QA  
Sbjct: 1398 TGTQTPTSTPITTTTT-------VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPT 1450

Query: 2202 PNGTVQRFLFTP------LATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTL 2255
            P         TP        T  TT  TTTTTV+ T   TG Q  +  +    +    T+
Sbjct: 1451 PTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTA----ITTTTTV 1506

Query: 2256 PPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQP 2315
             P  +    P   Q  T+ P       T   +P   +  T   + T TTV+        P
Sbjct: 1507 TPTPT----PTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVT------PTP 1556

Query: 2316 THAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPI 2375
            T   +  P     +   +     +P   Q+P+   I  +T    +P   S   TT +   
Sbjct: 1557 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPIT 1616

Query: 2376 PIQPHTSLQIPSQGQ-----PQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQP 2430
                 T+   P+  Q     P S     + T T ++G T      S+    +L    P P
Sbjct: 1617 TTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPP 1676

Query: 2431 Q 2431
            +
Sbjct: 1677 E 1677



 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 118/522 (22%), Positives = 181/522 (34%), Gaps = 62/522 (11%)

Query: 1585 ITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENCAKSTVT--TTTTTVTKLSTPSTGG 1642
            +T+ TTMT+T  TE+ T   +      T   +  +   +T T  TTTTTVT   TP TG 
Sbjct: 1297 VTQPTTMTTTT-TENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTP-TGT 1354

Query: 1643 SVDIISVKEQSKTVV---TTTVTDSLTTTGGTLVTSMT-----VSKEYSTRDKVKLMKFS 1694
                 +    + TV    T T T + TTT  T  T++T        +  T   +      
Sbjct: 1355 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1414

Query: 1695 RPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIW 1754
             P  T +GT  P+     T +   ++   P     +      I           P     
Sbjct: 1415 TPTPTPTGTQTPTTTPITTTT---TVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQT 1471

Query: 1755 PYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSET 1814
            P  +P     IT    +    +  G          ++         P   G T+T TS T
Sbjct: 1472 PTTTP-----ITTTTTVTPTPTPTGTQTPTP---TAITTTTTVTPTPTPTG-TQTPTS-T 1521

Query: 1815 EITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLR---------SS 1865
             ITTT  +      P G ++         P  +  T   TPTP   G +         ++
Sbjct: 1522 PITTTTTVTPTPT-PTGTQTP-------TPTPISTTTTVTPTPTPTGTQTPTTTPITTTT 1573

Query: 1866 ALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKP 1925
             + P    T  QT   ++ T               +  V                  Q P
Sbjct: 1574 TVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTP 1633

Query: 1926 TVIATSTT---SPT-SSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQN 1981
            T+I  STT   +PT + TT +  P      API+          LTT    P + T Q +
Sbjct: 1634 TMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIA---------ELTTSNPPPESSTPQTS 1684

Query: 1982 KNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFT---SFQPRTATVTIRPN 2038
            +    + ++ + +  +    +    ++    P ST T+  T +   +  P  +T T  P 
Sbjct: 1685 R----STSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPG 1740

Query: 2039 TSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRT 2080
            T   G TT +S   T   ++   T   TP        +IIRT
Sbjct: 1741 TPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRT 1782



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 35/122 (28%), Positives = 55/122 (45%), Gaps = 5/122 (4%)

Query: 1583 TVITEVTTMTST---VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPS 1639
            T IT  TT+T T     T++ T + +      T   +  +   +TVT  TTT T  +TP+
Sbjct: 1567 TPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPT 1626

Query: 1640 TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKT 1699
              G+     +   + T VT T T +  +TG    TS     E +T +     + S P+ +
Sbjct: 1627 PTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPP--ESSTPQTS 1684

Query: 1700 RS 1701
            RS
Sbjct: 1685 RS 1686



 Score = 40.0 bits (92), Expect = 0.034
 Identities = 99/500 (19%), Positives = 159/500 (31%), Gaps = 64/500 (12%)

Query: 1503 TLPSTKESDSTQTTTPS--------ASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEE 1554
            T P+T  + +T+  TP+           P   S        I T+     T +P  ++  
Sbjct: 1298 TQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTP 1357

Query: 1555 SNL---SNDFIDENGLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQ 1611
            +     +   +     P              T +T   T T T  T + T I        
Sbjct: 1358 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTSTPITTTTTVTP 1416

Query: 1612 TVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGGT 1671
            T   +      +T  TTTTTVT   TP+   +    ++   S    T T T + T T   
Sbjct: 1417 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTP 1476

Query: 1672 LVTSMTVSK-------EYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLP 1724
            + T+ TV+        +  T   +       P  T +GT  P+     T +   ++   P
Sbjct: 1477 ITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTT---TVTPTP 1533

Query: 1725 NDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLML 1784
                 +      I           P     P  +P     IT    +    +  G     
Sbjct: 1534 TPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTP-----ITTTTTVTPTPTPTGTQTPT 1588

Query: 1785 RLLWASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICP 1844
             +L  +          P    T+   T+ T ITTT  +      P G ++   I     P
Sbjct: 1589 TVLITT-----TTTMTPTPTPTSTKSTTVTPITTTTTVTATPT-PTGTQTPTMI-----P 1637

Query: 1845 IGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERV 1904
            I    T   TPTP                T   TGP    +     EL        +   
Sbjct: 1638 ISTTTTVTPTPTP----------------TTGSTGPPTHTSTAPIAELTTSNPPPESSTP 1681

Query: 1905 EKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTS--------TISPAQKVMVAPISG 1956
            +  ++ +        L    P  I  ++T+P S+ T+        T+SP      +P  G
Sbjct: 1682 QTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSP-PG 1740

Query: 1957 SVTTGTKMVLTTKVGSPATV 1976
            + T GT    ++   +P+TV
Sbjct: 1741 TPTRGT-TTGSSSAPTPSTV 1759


>gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 [Homo
            sapiens]
          Length = 898

 Score = 84.3 bits (207), Expect = 2e-15
 Identities = 99/377 (26%), Positives = 155/377 (41%), Gaps = 61/377 (16%)

Query: 2174 QTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTT-A 2232
            Q T Q  L P  V V   P Q  +    P    Q+   T  +TT     +++ T+     
Sbjct: 153  QATRQSLLGPPPVGVPMNPSQFNLSGRNP----QKQARTSSSTTPNRKDSSSQTMPVEDK 208

Query: 2233 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPE 2292
            +   E  +    P+M   +D+ LPP       P +   +   P+ +P+P    + PA+  
Sbjct: 209  SDPPEGSEEAAEPRMDTPEDQDLPPC------PEDIAKEKRTPAPEPEPCEASELPAK-- 260

Query: 2293 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIR 2352
                         SS  P+E +P        Q+  ++QPQ+        R+  P QT+  
Sbjct: 261  ----------RLRSSEEPTEKEPPG------QLQVKAQPQA--------RMTVPKQTQ-- 294

Query: 2353 PSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQ 2412
              TP  L    ++QV          QP   LQ+ +Q Q Q+QP++ S+   +        
Sbjct: 295  --TPDLLPEALEAQVLPR------FQPRV-LQVQAQVQSQTQPRIPSTDTQVQPKLQKQA 345

Query: 2413 VTVSSPSRPQLQIQQPQPQV--IAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVP-QQIKL 2469
             T +SP    LQ +Q QPQ+   A PQ Q Q QV  Q  SQ   Q+Q QQ   P +Q++ 
Sbjct: 346  QTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQP 405

Query: 2470 QL----------PIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQI 2519
            Q+           +Q+Q    VQT     V T    SVQ Q     Q+  Q  ++  +Q 
Sbjct: 406  QVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQP 465

Query: 2520 EIKREHTLQASNQSEII 2536
              + + +L A  Q+ ++
Sbjct: 466  HTQPQVSLLAPEQTPVV 482



 Score = 61.6 bits (148), Expect = 1e-08
 Identities = 65/225 (28%), Positives = 93/225 (41%), Gaps = 23/225 (10%)

Query: 2177 GQLQLIPQGVTVLPGPGQ----QLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTA 2232
            GQLQ+  Q    +  P Q     L+  A+    + RF    L   A   S T   + +T 
Sbjct: 275  GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD 334

Query: 2233 AGTG----EQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSP 2288
                    +Q Q++ SP+  V Q K + P         EA+PQ  Q   Q QPQ   Q P
Sbjct: 335  TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQ-----EAEPQK-QVQPQVQPQAHSQGP 388

Query: 2289 AQPEVQTQPE----VQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQ 2344
             Q ++Q + E    VQ Q    +H     Q    Q  K QV  Q+ PQ + Q Q  V+ Q
Sbjct: 389  RQVQLQQEAEPLKQVQPQVQPQAHSQPPRQ-VQLQLQK-QVQTQTYPQVHTQAQPSVQPQ 446

Query: 2345 S--PSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHT-SLQIP 2386
               P+Q  ++P   +   P  Q QV     +  P+  H   L++P
Sbjct: 447  EHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP 491



 Score = 33.5 bits (75), Expect = 3.2
 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 16/102 (15%)

Query: 2416 SSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQ------AQQSGVPQQIKL 2469
            S   + QLQ QQ Q Q +   QLQQQ     Q+Q Q + Q+Q        Q+ +P  +  
Sbjct: 3    SQQQQQQLQQQQQQLQQLQQQQLQQQ-----QLQQQQLLQLQQLLQQSPPQAPLPMAVSR 57

Query: 2470 QLPIQIQQS-----SAVQTHQIQNVVTVQAASVQEQLQRVQQ 2506
             LP Q  Q          +  + N   +Q A + +QLQ + Q
Sbjct: 58   GLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQ 99



 Score = 32.7 bits (73), Expect = 5.4
 Identities = 96/470 (20%), Positives = 150/470 (31%), Gaps = 63/470 (13%)

Query: 1844 PIGVPETPKETP----TPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRA 1899
            P+GVP  P +       PQ++   SS+  P R ++  QT PV  ++   E   E  E R 
Sbjct: 164  PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 223

Query: 1900 FAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVT 1959
                 +++     E  AK++           ++  P     S+  P +K     +     
Sbjct: 224  DTPE-DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQ 282

Query: 1960 TGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTS 2019
               +M +  +  +P  +           F   V Q Q+     QVQ +    IPS     
Sbjct: 283  PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQA-----QVQSQTQPRIPS----- 332

Query: 2020 QQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIR 2079
              T T  QP+               T+    V+   Q++P +     P +Q         
Sbjct: 333  --TDTQVQPKL-------QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQ--------- 374

Query: 2080 TPVMVQPGA----PQQVMTQIIRGQPVSTAVS--APNTVSSTPGQKSLTSATSTSNIQSS 2133
                VQP A    P+QV  Q    +P+        P   S  P Q  L        +Q  
Sbjct: 375  VQPQVQPQAHSQGPRQVQLQ-QEAEPLKQVQPQVQPQAHSQPPRQVQL-------QLQKQ 426

Query: 2134 ASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPG 2193
                  PQ      T AQ +   Q H   Q   V +Q   QT  Q    PQ   + P   
Sbjct: 427  VQTQTYPQVH----TQAQPSVQPQEHPPAQ---VSVQPPEQTHEQPHTQPQVSLLAPEQT 479

Query: 2194 QQLM---------QAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLS 2244
              ++          A    G +++ L  P+ T  +       +      G  E R  ++ 
Sbjct: 480  PVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMP 539

Query: 2245 PQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQ 2294
                      +   QSS        P T  P       + P + + P  Q
Sbjct: 540  GVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQ 589


>gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [Homo
            sapiens]
          Length = 898

 Score = 84.3 bits (207), Expect = 2e-15
 Identities = 99/377 (26%), Positives = 155/377 (41%), Gaps = 61/377 (16%)

Query: 2174 QTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTT-A 2232
            Q T Q  L P  V V   P Q  +    P    Q+   T  +TT     +++ T+     
Sbjct: 153  QATRQSLLGPPPVGVPMNPSQFNLSGRNP----QKQARTSSSTTPNRKDSSSQTMPVEDK 208

Query: 2233 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPE 2292
            +   E  +    P+M   +D+ LPP       P +   +   P+ +P+P    + PA+  
Sbjct: 209  SDPPEGSEEAAEPRMDTPEDQDLPPC------PEDIAKEKRTPAPEPEPCEASELPAK-- 260

Query: 2293 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIR 2352
                         SS  P+E +P        Q+  ++QPQ+        R+  P QT+  
Sbjct: 261  ----------RLRSSEEPTEKEPPG------QLQVKAQPQA--------RMTVPKQTQ-- 294

Query: 2353 PSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQ 2412
              TP  L    ++QV          QP   LQ+ +Q Q Q+QP++ S+   +        
Sbjct: 295  --TPDLLPEALEAQVLPR------FQPRV-LQVQAQVQSQTQPRIPSTDTQVQPKLQKQA 345

Query: 2413 VTVSSPSRPQLQIQQPQPQV--IAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVP-QQIKL 2469
             T +SP    LQ +Q QPQ+   A PQ Q Q QV  Q  SQ   Q+Q QQ   P +Q++ 
Sbjct: 346  QTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQP 405

Query: 2470 QL----------PIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQI 2519
            Q+           +Q+Q    VQT     V T    SVQ Q     Q+  Q  ++  +Q 
Sbjct: 406  QVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQP 465

Query: 2520 EIKREHTLQASNQSEII 2536
              + + +L A  Q+ ++
Sbjct: 466  HTQPQVSLLAPEQTPVV 482



 Score = 61.6 bits (148), Expect = 1e-08
 Identities = 65/225 (28%), Positives = 93/225 (41%), Gaps = 23/225 (10%)

Query: 2177 GQLQLIPQGVTVLPGPGQ----QLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTA 2232
            GQLQ+  Q    +  P Q     L+  A+    + RF    L   A   S T   + +T 
Sbjct: 275  GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD 334

Query: 2233 AGTG----EQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSP 2288
                    +Q Q++ SP+  V Q K + P         EA+PQ  Q   Q QPQ   Q P
Sbjct: 335  TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQ-----EAEPQK-QVQPQVQPQAHSQGP 388

Query: 2289 AQPEVQTQPE----VQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQ 2344
             Q ++Q + E    VQ Q    +H     Q    Q  K QV  Q+ PQ + Q Q  V+ Q
Sbjct: 389  RQVQLQQEAEPLKQVQPQVQPQAHSQPPRQ-VQLQLQK-QVQTQTYPQVHTQAQPSVQPQ 446

Query: 2345 S--PSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHT-SLQIP 2386
               P+Q  ++P   +   P  Q QV     +  P+  H   L++P
Sbjct: 447  EHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP 491



 Score = 33.5 bits (75), Expect = 3.2
 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 16/102 (15%)

Query: 2416 SSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQ------AQQSGVPQQIKL 2469
            S   + QLQ QQ Q Q +   QLQQQ     Q+Q Q + Q+Q        Q+ +P  +  
Sbjct: 3    SQQQQQQLQQQQQQLQQLQQQQLQQQ-----QLQQQQLLQLQQLLQQSPPQAPLPMAVSR 57

Query: 2470 QLPIQIQQS-----SAVQTHQIQNVVTVQAASVQEQLQRVQQ 2506
             LP Q  Q          +  + N   +Q A + +QLQ + Q
Sbjct: 58   GLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQ 99



 Score = 32.7 bits (73), Expect = 5.4
 Identities = 96/470 (20%), Positives = 150/470 (31%), Gaps = 63/470 (13%)

Query: 1844 PIGVPETPKETP----TPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRA 1899
            P+GVP  P +       PQ++   SS+  P R ++  QT PV  ++   E   E  E R 
Sbjct: 164  PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 223

Query: 1900 FAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVT 1959
                 +++     E  AK++           ++  P     S+  P +K     +     
Sbjct: 224  DTPE-DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQ 282

Query: 1960 TGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTS 2019
               +M +  +  +P  +           F   V Q Q+     QVQ +    IPS     
Sbjct: 283  PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQA-----QVQSQTQPRIPS----- 332

Query: 2020 QQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIR 2079
              T T  QP+               T+    V+   Q++P +     P +Q         
Sbjct: 333  --TDTQVQPKL-------QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQ--------- 374

Query: 2080 TPVMVQPGA----PQQVMTQIIRGQPVSTAVS--APNTVSSTPGQKSLTSATSTSNIQSS 2133
                VQP A    P+QV  Q    +P+        P   S  P Q  L        +Q  
Sbjct: 375  VQPQVQPQAHSQGPRQVQLQ-QEAEPLKQVQPQVQPQAHSQPPRQVQL-------QLQKQ 426

Query: 2134 ASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPG 2193
                  PQ      T AQ +   Q H   Q   V +Q   QT  Q    PQ   + P   
Sbjct: 427  VQTQTYPQVH----TQAQPSVQPQEHPPAQ---VSVQPPEQTHEQPHTQPQVSLLAPEQT 479

Query: 2194 QQLM---------QAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLS 2244
              ++          A    G +++ L  P+ T  +       +      G  E R  ++ 
Sbjct: 480  PVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMP 539

Query: 2245 PQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQ 2294
                      +   QSS        P T  P       + P + + P  Q
Sbjct: 540  GVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQ 589


>gi|46399200 testis-specific bromodomain protein [Homo sapiens]
          Length = 947

 Score = 84.0 bits (206), Expect = 2e-15
 Identities = 40/94 (42%), Positives = 54/94 (57%), Gaps = 2/94 (2%)

Query: 2811 KRVLRSLQAHKMAWPFLEPVDPN--DAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVA 2868
            K VL+ L  H  +WPF  PVD      PDYY +IK PMDL T+++R++ +YY K +E + 
Sbjct: 37   KVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIE 96

Query: 2869 DMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKL 2902
            D   +F NC  YN         A+ LE  F+QKL
Sbjct: 97   DFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKL 130



 Score = 67.8 bits (164), Expect = 2e-10
 Identities = 35/91 (38%), Positives = 51/91 (56%), Gaps = 5/91 (5%)

Query: 2813 VLRSLQAHK---MAWPFLEPVDPN--DAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFV 2867
            +L+ + A K    AWPF  PVD N     +YY V+K PMDL T++E++  + Y+   +F 
Sbjct: 279  ILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFA 338

Query: 2868 ADMTKIFDNCRYYNPSDSPFYQCAEVLESFF 2898
            AD+  +F NC  YNP D      A +L+  F
Sbjct: 339  ADVRLMFMNCYKYNPPDHEVVTMARMLQDVF 369



 Score = 36.2 bits (82), Expect = 0.49
 Identities = 75/341 (21%), Positives = 134/341 (39%), Gaps = 61/341 (17%)

Query: 829  CAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPV 888
            C +K  +     RE+         +S + E+ E+VK+  K QE+ + + Q   V    P 
Sbjct: 387  CYIKTDITETTGRENTNEASSEGNSSDDSED-ERVKRLAKLQEQLKAVHQQLQVLSQVPF 445

Query: 889  -KHQVWKQKGEEYRVTGYGGWSWISKTHVYRFVPKLPGNTNVNYRKSLEGTKNNMDENMD 947
             K    K+K ++ +           K  V         N+N N RK  E  +      + 
Sbjct: 446  RKLNKKKEKSKKEK----------KKEKV--------NNSNENPRKMCEQMR------LK 481

Query: 948  ESDKRKCSRSPKKIKIEPDSEKDEVKGSDAAKGADQNE-----MDISKITEKKDQDVKEL 1002
            E  KR     PKK K +    K E    D AK  + +E     ++I+K+   K   V  +
Sbjct: 482  EKSKR---NQPKKRKQQFIGLKSE--DEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHI 536

Query: 1003 LDSDSDKPCKEEPMEVDDDMKTESHVNCQESSQVDVVNVSEGFHLRTSYKKKTKSSKLDG 1062
            + S         P E++ D +T      +E  +          ++    +K+        
Sbjct: 537  IQSREPSLSNSNPDEIEIDFETLKASTLRELEK----------YVSACLRKRPLKPPAKK 586

Query: 1063 LLERRIKQFTLEEKQRLEKIKLEGGIKGIGKTSTNSSKNLSESPVITKAKEGCQSDSMRQ 1122
            ++  + ++   ++KQ LEK  L+           NS K  ++S   T+  +  ++ S   
Sbjct: 587  IMMSK-EELHSQKKQELEKRLLD------VNNQLNSRKRQTKSDK-TQPSKAVENVSRLS 638

Query: 1123 EQSPNANNDQPEDLIQGCSESDSSVLRMSDPSHTTNKLYPK 1163
            E S ++++          SES SS L  SD S + ++++PK
Sbjct: 639  ESSSSSSSSSE-------SESSSSDLSSSDSSDSESEMFPK 672



 Score = 33.5 bits (75), Expect = 3.2
 Identities = 72/307 (23%), Positives = 118/307 (38%), Gaps = 62/307 (20%)

Query: 1370 RPVNKCSDQIKLKNTTDKKNNENRESEKKGQRTSTFQINGKDNKPK------IYLKGE-- 1421
            R +NK  ++ K +   +K NN N E+ +K       +   K N+PK      I LK E  
Sbjct: 446  RKLNKKKEKSKKEKKKEKVNNSN-ENPRKMCEQMRLKEKSKRNQPKKRKQQFIGLKSEDE 504

Query: 1422 ---CLKEISESRVVSGNV------------------EPKVNNINKIIPENDIKSLTVKES 1460
                     E R +S N+                  EP ++N N    E +I   T+K S
Sbjct: 505  DNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPSLSNSNP--DEIEIDFETLKAS 562

Query: 1461 AIRPFINGDVIMEDFNERN-SSETKSHLLSSSDAEGNYRDSLE--TLPSTKESDSTQTTT 1517
             +R       +     +R      K  ++S  +     +  LE   L    + +S +  T
Sbjct: 563  TLREL--EKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQELEKRLLDVNNQLNSRKRQT 620

Query: 1518 PSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNG 1577
             S     S +V  V  +   +S      SS  +SE ES+ S+         ++ +++ + 
Sbjct: 621  KSDKTQPSKAVENVSRLSESSS------SSSSSSESESSSSD---------LSSSDSSDS 665

Query: 1578 ESKRKTVITEVTTMTSTVATESKTVIKVEKG-----DKQTVVSSTENCAKSTVTTTTTTV 1632
            ES+     TEV    S     SK  +K  K      + +T V+    C + T T+  TT+
Sbjct: 666  ESEMFPKFTEVKPNDS----PSKENVKKMKNECILPEGRTGVTQIGYCVQDT-TSANTTL 720

Query: 1633 TKLSTPS 1639
               +TPS
Sbjct: 721  VHQTTPS 727


>gi|46399198 testis-specific bromodomain protein [Homo sapiens]
          Length = 947

 Score = 84.0 bits (206), Expect = 2e-15
 Identities = 40/94 (42%), Positives = 54/94 (57%), Gaps = 2/94 (2%)

Query: 2811 KRVLRSLQAHKMAWPFLEPVDPN--DAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVA 2868
            K VL+ L  H  +WPF  PVD      PDYY +IK PMDL T+++R++ +YY K +E + 
Sbjct: 37   KVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIE 96

Query: 2869 DMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKL 2902
            D   +F NC  YN         A+ LE  F+QKL
Sbjct: 97   DFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKL 130



 Score = 67.8 bits (164), Expect = 2e-10
 Identities = 35/91 (38%), Positives = 51/91 (56%), Gaps = 5/91 (5%)

Query: 2813 VLRSLQAHK---MAWPFLEPVDPN--DAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFV 2867
            +L+ + A K    AWPF  PVD N     +YY V+K PMDL T++E++  + Y+   +F 
Sbjct: 279  ILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFA 338

Query: 2868 ADMTKIFDNCRYYNPSDSPFYQCAEVLESFF 2898
            AD+  +F NC  YNP D      A +L+  F
Sbjct: 339  ADVRLMFMNCYKYNPPDHEVVTMARMLQDVF 369



 Score = 36.2 bits (82), Expect = 0.49
 Identities = 75/341 (21%), Positives = 134/341 (39%), Gaps = 61/341 (17%)

Query: 829  CAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPV 888
            C +K  +     RE+         +S + E+ E+VK+  K QE+ + + Q   V    P 
Sbjct: 387  CYIKTDITETTGRENTNEASSEGNSSDDSED-ERVKRLAKLQEQLKAVHQQLQVLSQVPF 445

Query: 889  -KHQVWKQKGEEYRVTGYGGWSWISKTHVYRFVPKLPGNTNVNYRKSLEGTKNNMDENMD 947
             K    K+K ++ +           K  V         N+N N RK  E  +      + 
Sbjct: 446  RKLNKKKEKSKKEK----------KKEKV--------NNSNENPRKMCEQMR------LK 481

Query: 948  ESDKRKCSRSPKKIKIEPDSEKDEVKGSDAAKGADQNE-----MDISKITEKKDQDVKEL 1002
            E  KR     PKK K +    K E    D AK  + +E     ++I+K+   K   V  +
Sbjct: 482  EKSKR---NQPKKRKQQFIGLKSE--DEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHI 536

Query: 1003 LDSDSDKPCKEEPMEVDDDMKTESHVNCQESSQVDVVNVSEGFHLRTSYKKKTKSSKLDG 1062
            + S         P E++ D +T      +E  +          ++    +K+        
Sbjct: 537  IQSREPSLSNSNPDEIEIDFETLKASTLRELEK----------YVSACLRKRPLKPPAKK 586

Query: 1063 LLERRIKQFTLEEKQRLEKIKLEGGIKGIGKTSTNSSKNLSESPVITKAKEGCQSDSMRQ 1122
            ++  + ++   ++KQ LEK  L+           NS K  ++S   T+  +  ++ S   
Sbjct: 587  IMMSK-EELHSQKKQELEKRLLD------VNNQLNSRKRQTKSDK-TQPSKAVENVSRLS 638

Query: 1123 EQSPNANNDQPEDLIQGCSESDSSVLRMSDPSHTTNKLYPK 1163
            E S ++++          SES SS L  SD S + ++++PK
Sbjct: 639  ESSSSSSSSSE-------SESSSSDLSSSDSSDSESEMFPK 672



 Score = 33.5 bits (75), Expect = 3.2
 Identities = 72/307 (23%), Positives = 118/307 (38%), Gaps = 62/307 (20%)

Query: 1370 RPVNKCSDQIKLKNTTDKKNNENRESEKKGQRTSTFQINGKDNKPK------IYLKGE-- 1421
            R +NK  ++ K +   +K NN N E+ +K       +   K N+PK      I LK E  
Sbjct: 446  RKLNKKKEKSKKEKKKEKVNNSN-ENPRKMCEQMRLKEKSKRNQPKKRKQQFIGLKSEDE 504

Query: 1422 ---CLKEISESRVVSGNV------------------EPKVNNINKIIPENDIKSLTVKES 1460
                     E R +S N+                  EP ++N N    E +I   T+K S
Sbjct: 505  DNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPSLSNSNP--DEIEIDFETLKAS 562

Query: 1461 AIRPFINGDVIMEDFNERN-SSETKSHLLSSSDAEGNYRDSLE--TLPSTKESDSTQTTT 1517
             +R       +     +R      K  ++S  +     +  LE   L    + +S +  T
Sbjct: 563  TLREL--EKYVSACLRKRPLKPPAKKIMMSKEELHSQKKQELEKRLLDVNNQLNSRKRQT 620

Query: 1518 PSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNG 1577
             S     S +V  V  +   +S      SS  +SE ES+ S+         ++ +++ + 
Sbjct: 621  KSDKTQPSKAVENVSRLSESSS------SSSSSSESESSSSD---------LSSSDSSDS 665

Query: 1578 ESKRKTVITEVTTMTSTVATESKTVIKVEKG-----DKQTVVSSTENCAKSTVTTTTTTV 1632
            ES+     TEV    S     SK  +K  K      + +T V+    C + T T+  TT+
Sbjct: 666  ESEMFPKFTEVKPNDS----PSKENVKKMKNECILPEGRTGVTQIGYCVQDT-TSANTTL 720

Query: 1633 TKLSTPS 1639
               +TPS
Sbjct: 721  VHQTTPS 727


>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
            sapiens]
          Length = 1905

 Score = 83.6 bits (205), Expect = 3e-15
 Identities = 38/100 (38%), Positives = 55/100 (55%)

Query: 2813 VLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTK 2872
            +L  +++H  AWPFLEPV+P     Y  +IK PMD +TM ER+ R  Y    EF AD   
Sbjct: 1805 ILMEMESHDAAWPFLEPVNPRLVSGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAADALL 1864

Query: 2873 IFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHN 2912
            +FDNC+ +N  DS   +   ++  FF  + + F   +  N
Sbjct: 1865 VFDNCQTFNEDDSEVGKAGHIMRRFFESRWEEFYQGKQAN 1904



 Score = 55.8 bits (133), Expect = 6e-07
 Identities = 76/331 (22%), Positives = 135/331 (40%), Gaps = 40/331 (12%)

Query: 2111 TVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQ 2170
            ++++ PG++          + ++AS  P  ++   KL+  QL    +    +Q L  V  
Sbjct: 1061 SIAAVPGRRGRRDG----EVDATASSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSL 1116

Query: 2171 GQGQTTGQLQLIPQ--GVTVLPGPGQQLMQAAMPNGT------VQRFLFTPLATTATTAS 2222
            GQ +   +  ++P   G+ V    G  + +  +   T          L   L +     +
Sbjct: 1117 GQDRYRRRYWVLPYLAGIFVEGTEGNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELA 1176

Query: 2223 TTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQ 2282
             + TT S+ A   G  R++K       H              P   Q  + QP AQ QP+
Sbjct: 1177 GSNTTASSPARARGRPRKTKPGSMQPRHLKS-----------PVRGQ-DSEQPQAQLQPE 1224

Query: 2283 TQPQSPAQPEVQTQPEVQTQTTVSSHVPS-----EAQPTHAQSSKPQVAAQSQPQSNVQG 2337
             Q  +PAQP+ Q Q ++Q+         S     ++Q   +QS+     +Q+Q  S++  
Sbjct: 1225 AQLHAPAQPQPQLQLQLQSHKGFLEQEGSPLSLGQSQHDLSQSAFLSWLSQTQSHSSLLS 1284

Query: 2338 QSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIP--IQPHTSLQIPSQGQPQSQP 2395
             S V     S  ++ P+ PSQ  P ++ +     S P P  +  + S Q+P    P   P
Sbjct: 1285 SS-VLTPDSSPGKLDPA-PSQ--PPEEPEPDEAESSPDPQALWFNISAQMPCNAAPTPPP 1340

Query: 2396 QVQS-----STQTLSSGQTLNQVTVSSPSRP 2421
             V       S Q L+S + +N+ + ++P  P
Sbjct: 1341 AVSEDQPTPSPQQLASSKPMNRPSAANPCSP 1371



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 24/53 (45%), Positives = 31/53 (58%), Gaps = 5/53 (9%)

Query: 393  CRVCHKLGD----LLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPG 441
            C VC K GD    LL C+ C    H+ C +P +E VPE +W C VC+A +V G
Sbjct: 1679 CLVCRK-GDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCLAQQVEG 1730



 Score = 35.0 bits (79), Expect = 1.1
 Identities = 29/130 (22%), Positives = 60/130 (46%), Gaps = 11/130 (8%)

Query: 2505 QQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQK--KSMTPAER 2562
            Q+  +++ K K  + + K    +Q       IQ Q   K     + LKQK  K  + AE+
Sbjct: 699  QETLNEEDKAKIAKSKKKMRQKVQRGECQTTIQGQARNKRKQETKSLKQKEAKKKSKAEK 758

Query: 2563 EENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQK---RSKQNATKLSALLFKHK 2619
            E+ +         + + +K+ +E+K+  K +++EE  + K   ++ +       L  + +
Sbjct: 759  EKGKTK------QEKLKEKVKREKKEKVKMKEKEEVTKAKPACKADKTLATQRRLEERQR 812

Query: 2620 EQLRAEILKK 2629
            +Q+  E +KK
Sbjct: 813  QQMILEEMKK 822



 Score = 32.0 bits (71), Expect = 9.2
 Identities = 29/129 (22%), Positives = 53/129 (41%), Gaps = 9/129 (6%)

Query: 2318 AQSSKPQVAAQSQPQSNV----QGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQ 2373
            A  + P V  +S  Q N      G    + +  +Q+   P + +Q +P Q S +Q   + 
Sbjct: 366  ASPTSPPVLGESVLQDNSFDLNNGSDAEQEEMETQSSDFPPSLTQPAPDQSSTIQLHPAT 425

Query: 2374 PIPIQPHT----SLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVT-VSSPSRPQLQIQQP 2428
               + P T    SL +     P+  P+V  +  T+ S    + V+  SS   P + ++ P
Sbjct: 426  SPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPAVFSVVSPASSAVLPAVSLEVP 485

Query: 2429 QPQVIAVPQ 2437
                +  P+
Sbjct: 486  LTASVTSPK 494



 Score = 32.0 bits (71), Expect = 9.2
 Identities = 31/127 (24%), Positives = 54/127 (42%), Gaps = 16/127 (12%)

Query: 999  VKELLDSDSDKPCKEEPMEVDDDMKTESHVNCQESSQVDVVNVSEGF-------HLRTSY 1051
            + ELL+   ++P K+  +E  + +  E      +S +     V  G          R   
Sbjct: 681  ITELLNKTDNRPLKK--LEAQETLNEEDKAKIAKSKKKMRQKVQRGECQTTIQGQARNKR 738

Query: 1052 KKKTKSSKLDGLLERRIKQFTLEEKQRLEKIKLEGGIKGIGKTSTNSSKNLSESPVITKA 1111
            K++TKS K     E + K    +EK + ++ KL+  +K   K        + E   +TKA
Sbjct: 739  KQETKSLKQK---EAKKKSKAEKEKGKTKQEKLKEKVKREKKEKVK----MKEKEEVTKA 791

Query: 1112 KEGCQSD 1118
            K  C++D
Sbjct: 792  KPACKAD 798


>gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]
          Length = 1073

 Score = 83.2 bits (204), Expect = 3e-15
 Identities = 204/855 (23%), Positives = 324/855 (37%), Gaps = 158/855 (18%)

Query: 1925 PTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNF 1984
            PT   +S+ SP S  T+  +P+    +   S + T+    V  T VGS        N N 
Sbjct: 276  PTSAVSSSGSPASVMTNMRAPSTTGGIGINSVTGTSTVNNVNITAVGS-------FNPNV 328

Query: 1985 HQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGG 2044
              +    V    SN             IPS+ G S          T+ V +   +    G
Sbjct: 329  TSSMLGNVNISTSN-------------IPSAAGVSVGPGV-----TSGVNVNILSGMGNG 370

Query: 2045 TTSNSQVITG-PQIRPGMT--VIRTPLQQSTLGKAIIRTPVMVQPGAP----QQVMTQII 2097
            T S+S  ++  P    GMT   + +  QQ T+  +  R   +     P    +   T+  
Sbjct: 371  TISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFY 430

Query: 2098 RGQ---PVSTAV---SAPNTVSSTPGQ-KSLTSATSTSNIQSSASQPPRPQQGQVKLTMA 2150
              +   P +  V       TV   P +  S   +TS S++ SS S            T++
Sbjct: 431  EKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVS------------TLS 478

Query: 2151 QLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIP--QGVTV------LPGPGQQLMQAAMP 2202
              T+ + G G     TVV+Q Q Q   Q Q  P  QGVT+        GP Q +   ++P
Sbjct: 479  HYTE-SVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGP-QSIPAVSIP 536

Query: 2203 NGTVQRFL-----------------FTPLATTATTASTT------TTTVSTTAAGTGEQR 2239
                Q  +                   P+   AT ++ T         V  T+A  G+Q 
Sbjct: 537  QSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSA-LGQQP 595

Query: 2240 QSKLSPQMQVHQDKTLPPAQSSSVGP--------AEAQPQTAQPSAQPQPQTQPQSPAQP 2291
                  Q Q+   +  PP Q+   G          + QP  +   A    ++  Q+PA  
Sbjct: 596  SISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASE 655

Query: 2292 EVQTQPEVQTQTTVSSHVPSE------------AQPTHAQSSKPQVAAQSQPQ-SNVQGQ 2338
             VQ QP +  QT +SS  PS             AQP   Q      A  +QP  ++VQ  
Sbjct: 656  YVQQQPIL--QTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQ-- 711

Query: 2339 SPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQ 2398
             PV  Q+P+     P+     + GQQ+ + T   QP    P + +Q   QG P S  QV 
Sbjct: 712  -PVG-QAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQ---QGAPPSS-QVV 765

Query: 2399 SSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQ-IQSQ------ 2451
               QT   G     V  S+PS PQ  +   Q  ++ VP   Q V+ ++Q I SQ      
Sbjct: 766  PPAQT---GIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVS 822

Query: 2452 ---------VVAQIQAQ-QSGVPQ-QIKLQLPIQIQQSSAVQT-HQIQNVVTVQAASVQE 2499
                     V +Q+ +   SG+P     L  P  I Q+ A Q  + +Q+V      +   
Sbjct: 823  SLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNT 882

Query: 2500 QLQRVQQL----RDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKK 2555
             L   QQ+         +   Q I  + E   +A+  S +   Q +   +  +  +    
Sbjct: 883  NLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGS 942

Query: 2556 SMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALL 2615
            S + A        +   +V+      +D E++ ++       +++ K  +      S L+
Sbjct: 943  SSSLAA----SASLFPLKVLPLTTPLVDGEDESSS--GASVVAIDNKIEQAMDLVKSHLM 996

Query: 2616 FKHKEQLRAEILKK--RALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATA-VAAPCPP 2672
            +  +E++  E+LK+  + L++K+ Q+E +  L + L   +     QLAQ  A +    PP
Sbjct: 997  YAVREEV--EVLKEQIKELIEKNSQLEQENNLLKTLASPE-----QLAQFQAQLQTGSPP 1049

Query: 2673 VTPAPPAPPAPPPSP 2687
             T  P     PP  P
Sbjct: 1050 ATTQPQGTTQPPAQP 1064



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 105/447 (23%), Positives = 156/447 (34%), Gaps = 78/447 (17%)

Query: 2071 STLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNI 2130
            ST G +   TPV     AP   ++       V T + AP+T     G  S+T  ++ +N+
Sbjct: 263  STTGSSDSITPV-----APTSAVSSSGSPASVMTNMRAPSTTGGI-GINSVTGTSTVNNV 316

Query: 2131 QSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLP 2190
              +A     P      +T + L  +            V  G G T+G        V +L 
Sbjct: 317  NITAVGSFNPN-----VTSSMLGNVNISTSNIPSAAGVSVGPGVTSGV------NVNILS 365

Query: 2191 GPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQS---KLSPQM 2247
            G G         NGT+        +++A  +S        T      Q+Q      S   
Sbjct: 366  GMG---------NGTI--------SSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFR 408

Query: 2248 QVHQDKTLPPAQSSSVGPAE------AQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQT 2301
             V  D +  P +       E      A P T         +T  Q+P   EV ++ E  +
Sbjct: 409  VVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPI--EVTSERESTS 466

Query: 2302 QTTVSSHVPSEAQPTHAQSS----KPQVAAQSQPQSNVQGQSPVRVQSPS---------- 2347
             ++VSS V + +  T +  S     P V  Q Q Q   Q Q    +Q  +          
Sbjct: 467  GSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTG 526

Query: 2348 -QTRIRPSTPSQLSPGQQSQVQTTTS----------QPIPIQPHTSLQIPSQGQPQSQPQ 2396
             Q+    S P  +S  Q SQVQ  +           QP+P+Q   S     Q  P +   
Sbjct: 527  PQSIPAVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVG 586

Query: 2397 VQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQI 2456
            V S+      GQ   Q ++SS ++PQL   Q  P V          Q L   Q Q +   
Sbjct: 587  VTSAL-----GQ---QPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVST 638

Query: 2457 QAQQSGVPQQIKLQLPIQIQQSSAVQT 2483
            Q     V    +      +QQ   +QT
Sbjct: 639  QMAPGHVKSVTQNPASEYVQQQPILQT 665



 Score = 39.3 bits (90), Expect = 0.058
 Identities = 100/449 (22%), Positives = 147/449 (32%), Gaps = 80/449 (17%)

Query: 1914 QQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVA--PISGSVTTGTKMVLTTKVG 1971
            QQ      Q  P  + + T +P S         Q  M +  P S  V  GT ++    V 
Sbjct: 631  QQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVI---PVA 687

Query: 1972 SPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTA 2031
             P  +             T V    + + V  V Q    +    TG SQ      Q    
Sbjct: 688  QPQGIQLPVQP-------TAVPAQPAGASVQPVGQAPAAVSAVPTG-SQIANIGQQANIP 739

Query: 2032 TVTIRPNTSG-----SGGTTSNSQVITGPQ---IRPGMTVIRTPL-QQSTLGKAIIRTPV 2082
            T   +P+T         G   +SQV+   Q   I  G+      L QQ  +        V
Sbjct: 740  TAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTV 799

Query: 2083 MVQPGAPQQVMTQIIRGQ-------PVSTAVSAPNTVSST--------------PGQKSL 2121
              QP   + V   I+  Q       P ++++S  + VSST              P   + 
Sbjct: 800  PPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQ 859

Query: 2122 TSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQ--- 2178
            T AT   N+  S SQPP        L +AQ   L+      Q L   I  Q +   +   
Sbjct: 860  TPATQNGNLVQSVSQPPLIATN-TNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAE 918

Query: 2179 --LQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFT----PLATTATTASTTTTTVSTTA 2232
              L  +PQ ++   G    +   +  +      LF     PL T        +++ ++  
Sbjct: 919  PSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPLTTPLVDGEDESSSGASVV 978

Query: 2233 AGTG-------------------------EQRQSKLSPQMQVHQDKTLPPAQSS--SVGP 2265
            A                            EQ +  +    Q+ Q+  L    +S   +  
Sbjct: 979  AIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQ 1038

Query: 2266 AEAQPQTAQPSAQPQPQTQPQSPAQPEVQ 2294
             +AQ QT  P A  QPQ   Q PAQP  Q
Sbjct: 1039 FQAQLQTGSPPATTQPQGTTQPPAQPASQ 1067



 Score = 37.7 bits (86), Expect = 0.17
 Identities = 41/182 (22%), Positives = 69/182 (37%), Gaps = 43/182 (23%)

Query: 2256 PPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQP 2315
            PPA SS+ GP    PQ+    +Q Q Q QP +P      TQ + ++   ++S  P     
Sbjct: 68   PPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPG----GTQMKKKSGFQITSVTP----- 118

Query: 2316 THAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPI 2375
                         +Q  +++   + +   + S   +  S    LS  +   V        
Sbjct: 119  -------------AQISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSL------ 159

Query: 2376 PIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAV 2435
                       S+     +P+  SS +TL++ Q        SP++P L    PQP +  +
Sbjct: 160  -----------SRATDLGEPERSSSEETLNNFQEAETPGAVSPNQPHL----PQPHLPHL 204

Query: 2436 PQ 2437
            PQ
Sbjct: 205  PQ 206



 Score = 33.5 bits (75), Expect = 3.2
 Identities = 51/227 (22%), Positives = 89/227 (39%), Gaps = 29/227 (12%)

Query: 7   RPPKQPAAPAAERCAPAPPPPPPP--PTSGPIGGLRS--RHRGSSRGRWAAAQAEVAPKT 62
           +PP+  AA AA     A     P   P  G   G  S     G+  G  A +  +  P +
Sbjct: 3   QPPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPPPS 62

Query: 63  RLSSPRGGSSSRRKPPPPPPAPPS--TSAPGRGGRGGGGGRTGGGGGGGHLARTTAARRA 120
            L  P   +SS   P PPPP   +  + A  +      GG       G  +   T A+ +
Sbjct: 63  LLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQIS 122

Query: 121 VNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME 180
            + +  ++  +E+ E  +D+  +E   ED  + E  D       ++ E       PE   
Sbjct: 123 AS-ISSNNSIAEDTESYDDL--DESHTEDLSSSEILDVSLSRATDLGE-------PERSS 172

Query: 181 DDDDDASYCTESSFRSHSTYSSTPGR---RKPRVHRPRSPILEEKDI 224
            ++      T ++F+     + TPG     +P + +P  P L ++++
Sbjct: 173 SEE------TLNNFQE----AETPGAVSPNQPHLPQPHLPHLPQQNV 209



 Score = 33.1 bits (74), Expect = 4.1
 Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 6/79 (7%)

Query: 2671 PPVTPAPPAPPAPPPSPPPPPAVQHTGLLS------TPTLPAASQKRKREEEKDSSSKSK 2724
            PP    PP P A   S P PP  Q   LLS       P  P  +Q +K+   + +S    
Sbjct: 60   PPSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPA 119

Query: 2725 KKKMISTTSKETKKDTKLY 2743
            +     +++    +DT+ Y
Sbjct: 120  QISASISSNNSIAEDTESY 138


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 82.8 bits (203), Expect = 5e-15
 Identities = 133/747 (17%), Positives = 259/747 (34%), Gaps = 24/747 (3%)

Query: 926  NTNVNYRKSLEGTKNNMDENMDESDKRKCSRSPKKIKIEPDSEKDEVKGSDAAKGADQNE 985
            N N +  K  E   ++   + + SD      +      + DS K +   SD+      N 
Sbjct: 501  NGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNS 560

Query: 986  MDISKITEKKDQDVKELLDSDSDKPCKEEPMEVDDDMKTESHVNCQESSQVDVVNVSEGF 1045
             D S  ++    D     DSDS      +  + D    + S  +   S   D  + S+  
Sbjct: 561  SDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSS 620

Query: 1046 HLRT-SYKKKTKSSKLDGLLERRIKQFTLEEKQRLEKIKLEGGIKGIGKTSTNSSKNLSE 1104
              ++ S K ++ SS  D   +      +                      S++SS + S 
Sbjct: 621  DSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS 680

Query: 1105 SPVITKAKEGCQSDSMRQEQSPNANNDQPEDLIQGC-----SESDSSVLRMSDPSHTTNK 1159
            S     +     SDS    +S ++++    D          + SDS     SD S ++N 
Sbjct: 681  SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS 740

Query: 1160 LYPKDRVLDDVSIRSPETKCPKQNSIENDIEEKVSDLASRGQEPSKSKTKGNDFFIDDSK 1219
                D      S  S ++     +S  +D  +      S     S   +  +D       
Sbjct: 741  SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSD---SSDS 797

Query: 1220 LASADDIGTLICKNKKPLIQEESDTIVSSSKSALHSSVPKSTNDRDATPLSRAMDFEGKL 1279
              S+D   +    +       +S     SS S+  S    S++  D++  S   D +   
Sbjct: 798  SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSN 857

Query: 1280 GCDSESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLEPLKCELVSG 1339
              DS ++S   +SSD+ +  DSS+     ++SN S S    +   D +  +         
Sbjct: 858  RSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSD-SSNSSDSDSSDSSNSS--DS 914

Query: 1340 ESTGNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNNENRESEKKG 1399
              + N  D      +  N          +    +  S+     N++D  N+   +S    
Sbjct: 915  SDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS--DSSDSN 972

Query: 1400 QRTSTFQINGKDNKPKIYLKGECLKEISESRVVSGNVEPKVNNINKIIPENDIKSLTVKE 1459
               S+   N  D+              S +   S +     ++ N     N   S    +
Sbjct: 973  SSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSD 1032

Query: 1460 SAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPS 1519
            S      +      D ++ + S   S   +SSD+  +  DS ++  S+  SDS+ ++  S
Sbjct: 1033 S------SDSSDSSDSSDSSDSSDSSDSSNSSDSSDS-SDSSDSSDSSDSSDSSDSSESS 1085

Query: 1520 ASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNL--SNDFIDENGLPINKNENVNG 1577
             S   SNS +  +  +   S     +S    S + SN   S+D  D +    + N + + 
Sbjct: 1086 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS 1145

Query: 1578 ESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLST 1637
            +S   +  ++ ++ +S  +  S +    +  D      S+++   S  + ++ +     +
Sbjct: 1146 DSSESSDSSD-SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1204

Query: 1638 PSTGGSVDIISVKEQSKTVVTTTVTDS 1664
              +  S D     + S +  ++  +DS
Sbjct: 1205 SDSSDSSDSSDSSDSSDSSDSSDSSDS 1231



 Score = 74.7 bits (182), Expect = 1e-12
 Identities = 117/652 (17%), Positives = 228/652 (34%), Gaps = 20/652 (3%)

Query: 936  EGTKNNMDENMDESDKRKCSRSPKKIKIEPDSEK-DEVKGSDAAKGADQNEM-DISKITE 993
            + + +N  ++ D SD    S S         S+  D    SD++  +D ++  D S  +E
Sbjct: 641  DSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSE 700

Query: 994  KKDQ-DVKELLDSDSDKPCKEEPMEVDDDMKTESHVNCQESSQVDVVNVSEGFHLRTSYK 1052
              D  D  +   SDS         + D    ++S  +   S   D  + S       S  
Sbjct: 701  SSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD 760

Query: 1053 KKTKSSKLDGLLERRIKQFTLEEKQRLEKIKLEGGIKGIGKTSTNSSKNLSESPVITKAK 1112
                S   D          +            +         S+NSS +   S       
Sbjct: 761  SSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDS 820

Query: 1113 EGCQSDSMRQEQSPNANNDQPEDLIQGCSESDSSVLRMSDPSHTTNKLYPKDRVLDDVSI 1172
                  S   + S ++N+    D       SDS     SD S++++     D      S 
Sbjct: 821  SNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS 880

Query: 1173 RSPETKCPKQNSIENDIEEKVSDLASRGQEPSKSKTKGNDFFIDDSKLASADDIGTLICK 1232
             S ++     +S  +D        +S     S S    N    D S+ +++ D       
Sbjct: 881  DSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS--DSSESSNSSDNSNSSDS 938

Query: 1233 NKKPLIQEESDTIVSSSKS----ALHSSVPKSTNDRDATPLSRAMDF-EGKLGCDSESNS 1287
            +      + SD+  SS  S    + +SS    +N  D++  S + D  +     DS  +S
Sbjct: 939  SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS 998

Query: 1288 TLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLEPLKCELVSGESTGNCED 1347
               NSSD+    DSS+      +SN S S          +  +       S +S+ + + 
Sbjct: 999  DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD-------SSDSSDSSDS 1051

Query: 1348 RLPVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNNENRESEKKGQRTSTFQI 1407
                  ++++    S     +    +  SD  +  +++D  N+ +         +S    
Sbjct: 1052 SDSSNSSDSSDSSDSSDSS-DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSD 1110

Query: 1408 NGKDNKPKIYLKGECLKEISESRVVSGNVEPKVNNINKIIPENDIKSLTVKESAIRPFIN 1467
            +   +            + S+S   S +     ++ +    ++   S +   S      +
Sbjct: 1111 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSD 1170

Query: 1468 GDVIMEDFNERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNS 1527
                 +  N  +SS++     SS  ++ +  DS ++  S+  SDS+ ++  S S   S+S
Sbjct: 1171 SSDSSDSSNSSDSSDSSDSSDSSDSSDSS--DSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1228

Query: 1528 VNQVEDMEIETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGES 1579
             +  E  +   S     +S+   S + S+ S+   D N    +++++ NG +
Sbjct: 1229 SDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNN 1280



 Score = 73.2 bits (178), Expect = 4e-12
 Identities = 103/588 (17%), Positives = 219/588 (37%), Gaps = 42/588 (7%)

Query: 1096 TNSSKNLSESPVITKAKEGCQSDSMRQEQSPNANNDQPEDLIQGCSESDSSVLRMSDPSH 1155
            ++S K  S+S     +     SDS     S +++++   D     S+SDSS    SD S 
Sbjct: 540  SDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSD--SDSSDSDSSDSSDSDSSD 597

Query: 1156 TTNKLYPKDRVLDDVSIRSPETKCPKQNSIENDIEEKVSDLASRGQEPSKSKTKGNDFFI 1215
            ++N     D      S  S ++   K +S +++ +   SD  S   + + S +  N    
Sbjct: 598  SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSS 657

Query: 1216 DDSKLASADDIGTLICKNKKPLIQEESDTIVSSSKSALHSSVPKSTNDRDATPLSRAMDF 1275
            D S  +++ D               +S     SS S+  S+   S++  D++  S + D 
Sbjct: 658  DSSNSSNSSD-------------SSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDS 704

Query: 1276 EGKLGCDSESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLEPLKCE 1335
                  DS  +S   NS+ + S   +S +     NS++S      +   D          
Sbjct: 705  SDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNS 764

Query: 1336 LVSGESTGNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNNENRES 1395
              S +S+ + +       +++N    S     +    +  SD     +++D  ++ + +S
Sbjct: 765  SDSSDSSDSSDSSDSSNSSDSNDSSNSS----DSSDSSNSSDSSNSSDSSDSSDSSDSDS 820

Query: 1396 EKKGQRTSTFQINGKDNKPKIYLKGECLKEISESRVVSGNVEPKVNNINKIIPENDIKSL 1455
                  +++   +   N        +       S   S N     N+ +     +   S 
Sbjct: 821  SNSSDSSNSSDSSDSSNSSD---SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS 877

Query: 1456 TVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQT 1515
               +S+            D NE ++S   S   +SSD++ +         S+  SDS+ +
Sbjct: 878  DSSDSS------------DSNESSNSSDSSDSSNSSDSDSS--------DSSNSSDSSDS 917

Query: 1516 TTPSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENV 1575
            +  S S   SNS +     +   S     +S    S + SN S+     +    N +++ 
Sbjct: 918  SNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS 977

Query: 1576 NGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKL 1635
            +  +   +  +  ++ +S  +  S +    +  D     +S+++   S  + ++ +    
Sbjct: 978  DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037

Query: 1636 STPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYS 1683
             +  +  S D     + S +  ++  +DS  ++  +  +  + S E S
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESS 1085



 Score = 40.4 bits (93), Expect = 0.026
 Identities = 118/630 (18%), Positives = 228/630 (36%), Gaps = 48/630 (7%)

Query: 1069 KQFTLEEKQRLEKIKLEGGIKGIGKTSTNSSKNL--SESPVITKAKEGCQS--DSMRQEQ 1124
            K F+       E+  +EG     GK  T     +   E  +     +G  S  D+     
Sbjct: 91   KSFSTYSTLANEEGNIEGWNGDTGKAETYGHDGIHGKEENITANGIQGQVSIIDNAGATN 150

Query: 1125 SPNAN-----NDQPEDLIQGCSESDSSVLRMSDP--SHTTNKLYPKDRVLDDVSIRSPET 1177
              N N     N Q  D+       D +V++   P  + + N    +D ++        E 
Sbjct: 151  RSNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEII--------EN 202

Query: 1178 KCPKQNSIENDIEEKVSDLASRGQEPSKSKTKGNDFFIDDSKLASADDIGTLICKNKKPL 1237
             C  + +  ++I  +++   +  +E   +   G D  +D+S        G    +++   
Sbjct: 203  SCRNEGNT-SEITPQINSKRNGTKEAEVTPGTGEDAGLDNS---DGSPSGNGADEDEDEG 258

Query: 1238 IQEESDTIVSSSKSALHSSVPKSTNDRDATPLSRAMDFEGKLGCDSESNSTL--ENSSDT 1295
              ++ D    + K + ++S  +   D       +  D +  +G +S+S      E   D 
Sbjct: 259  SGDDEDEEAGNGKDSSNNSKGQEGQDH-----GKEDDHDSSIGQNSDSKEYYDPEGKEDP 313

Query: 1296 VSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLEPLKCELVSGESTGNCEDRLPVKGTE 1355
             +  D  +     +NS     +    R +D + L   + + V    T   E       T 
Sbjct: 314  HNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESE-------TH 366

Query: 1356 ANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNNENRESEKKGQRTSTF-QINGKDNKP 1414
            A GK  SQ K +E +  +  +     +N T +    N   E KGQ      + N K    
Sbjct: 367  AVGK--SQDKGIEIKGPSSGN-----RNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGE 419

Query: 1415 KIYLKGECLKEISESRVVSGNVEPKVNNINKIIPENDIKSLTVKESAIRPFINGDVIMED 1474
             + ++G   K    ++V   N     N+      + D KS+   +       NG+     
Sbjct: 420  VVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANS 479

Query: 1475 FNERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDM 1534
             ++ NSS       +S +++ N   S        +SDST  T  S S    N+ N  +D 
Sbjct: 480  ESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGN--DDN 537

Query: 1535 EIETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVITEVTTMTST 1594
            +   S   K  SS   S + SN S+     +    + N + + +S          + +S 
Sbjct: 538  DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSD 597

Query: 1595 VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVT-KLSTPSTGGSVDIISVKEQS 1653
             +  S +    +  D      S+++ + S+ + + ++ +   S  S   S D     + S
Sbjct: 598  SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSS 657

Query: 1654 KTVVTTTVTDSLTTTGGTLVTSMTVSKEYS 1683
             +  ++  +DS  ++  +  +S + S   S
Sbjct: 658  DSSNSSNSSDSSDSSDSSDSSSSSDSSNSS 687



 Score = 37.7 bits (86), Expect = 0.17
 Identities = 22/118 (18%), Positives = 45/118 (38%), Gaps = 2/118 (1%)

Query: 86  STSAPGRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEE 145
           ++ + G G  G         G G   +  + +  + N    D  +S + +  +   S + 
Sbjct: 523 NSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSS--DSSDSSDSDSSDSNSSSDS 580

Query: 146 EEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSST 203
           +  D D+ ++ DS+  +     +  D SD  +  +  D   S    S   S S+ S +
Sbjct: 581 DSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDS 638



 Score = 37.7 bits (86), Expect = 0.17
 Identities = 21/81 (25%), Positives = 34/81 (41%), Gaps = 5/81 (6%)

Query: 127  DDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDD-- 184
            D  +S +  +  D  +  +  +  D+ ++ DS D  +     D  DS    +  D  D  
Sbjct: 1164 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1223

Query: 185  ---DASYCTESSFRSHSTYSS 202
               D+S   ESS  S S+ SS
Sbjct: 1224 DSSDSSDSNESSDSSDSSDSS 1244



 Score = 37.4 bits (85), Expect = 0.22
 Identities = 31/132 (23%), Positives = 55/132 (41%), Gaps = 7/132 (5%)

Query: 536 DLTNKARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKDKNETEN-DSKDAEKNR 594
           D ++  +G + S  + +++    S  +   D D+  S   ++ D +++++ DS D++ + 
Sbjct: 538 DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSS- 596

Query: 595 EEFEDQSLEKDSDDKTPDDDPEQGKSEVGDFKSEKSNGELSESPGAGKGASGSTRIITRL 654
               D S   DS D +   D     S+  D KS+ S  E   S    K  S  +      
Sbjct: 597 ----DSSNSSDSSDSSDSSDSSDS-SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSS 651

Query: 655 RNPDSKLSQLKS 666
            N DS  S   S
Sbjct: 652 DNSDSSDSSNSS 663



 Score = 37.4 bits (85), Expect = 0.22
 Identities = 20/78 (25%), Positives = 35/78 (44%), Gaps = 3/78 (3%)

Query: 128 DHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDD---EEDEMEEDDDDSDYPEEMEDDDD 184
           D +S +     D     +  +  D+ ++ DS+ D    E +  + D  SD  +    D  
Sbjct: 592 DSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSS 651

Query: 185 DASYCTESSFRSHSTYSS 202
           D S  ++SS  S+S+ SS
Sbjct: 652 DNSDSSDSSNSSNSSDSS 669



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 74/380 (19%), Positives = 123/380 (32%), Gaps = 61/380 (16%)

Query: 940  NNMDENMDESDKRKCSRSPKKIKIEPDSEKDEVKGSDAAKGADQ-NEMDISKITEKKDQ- 997
            +N  ++ D SD    S S         S+  +   SD++  +D  N  D S  ++  D  
Sbjct: 980  SNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD--SSDSSNSSDSSNSSDSSNSSDSSDSS 1037

Query: 998  DVKELLDSDSDKPCKEEPMEVDDDMKTESHVNCQESSQVDVVNVSEGFHLRTSYKKKTKS 1057
            D  +  DS       +     D    ++S  +   S   D  + SE      S      S
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS 1097

Query: 1058 SKLDGLLERRIKQFTLEEKQRLEKIKLEGGIKGIGKTSTNSSKNLSESPVITKAKEGCQS 1117
               D                                + ++ S N S+S            
Sbjct: 1098 DSSDSS-------------------DSSDSSDSSDSSDSSDSSNSSDS----------SD 1128

Query: 1118 DSMRQEQSPNANNDQPEDLIQGCSESDSSVLRMSDPSHTTNKLYPKDRVLDDVSIRSPET 1177
             S   + S ++N+    D  +    SDS     SD S +++     D      S  S ++
Sbjct: 1129 SSDSSDSSDSSNSSDSSDSSESSDSSDS-----SDSSDSSDSSDSSDSSDSSDSSNSSDS 1183

Query: 1178 KCPKQNSIENDIEEKVSDLASRGQEPSKSKTKGNDFFIDDSKLASADDIGTLICKNKKPL 1237
                 +S  +D  +  SD +        S +  +    D S  + + D            
Sbjct: 1184 SDSSDSSDSSDSSDS-SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD------------ 1230

Query: 1238 IQEESDTIVSSSKSALHSSVPKSTNDRDATPLSRAMDFEGKLGCDSESNSTLENSSDTVS 1297
              E SD+  SS  S        S+N  D++  S + D       +S+S S   N ++  S
Sbjct: 1231 SNESSDSSDSSDSS-------DSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGS 1283

Query: 1298 IQDSSEEDMIVQNSNESISE 1317
              DS  E     +SN S S+
Sbjct: 1284 DSDSDSEG---SDSNHSTSD 1300



 Score = 36.2 bits (82), Expect = 0.49
 Identities = 21/84 (25%), Positives = 35/84 (41%), Gaps = 8/84 (9%)

Query: 127  DDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDD-- 184
            D  +S E  +  D  +  +  +  D+ ++ DS D  +     D  +S    +  D  D  
Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136

Query: 185  ------DASYCTESSFRSHSTYSS 202
                  D+S  +ESS  S S+ SS
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSS 1160



 Score = 35.8 bits (81), Expect = 0.64
 Identities = 18/73 (24%), Positives = 29/73 (39%), Gaps = 4/73 (5%)

Query: 127  DDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDA 186
            D +ES +  +  D        +  D+ ++ DS  D  DE +      +      D D D 
Sbjct: 1230 DSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSD- 1288

Query: 187  SYCTESSFRSHST 199
               +E S  +HST
Sbjct: 1289 ---SEGSDSNHST 1298



 Score = 35.4 bits (80), Expect = 0.83
 Identities = 20/76 (26%), Positives = 30/76 (39%), Gaps = 1/76 (1%)

Query: 127  DDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDA 186
            D   S +     D     +  +  D+ ++ DS D        D  DS    +   D  D+
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD-SSDSSDS 1078

Query: 187  SYCTESSFRSHSTYSS 202
            S  +ESS  S S+ SS
Sbjct: 1079 SDSSESSDSSDSSNSS 1094



 Score = 35.0 bits (79), Expect = 1.1
 Identities = 26/102 (25%), Positives = 48/102 (47%), Gaps = 17/102 (16%)

Query: 564 KGDIDNVKSPEETEKDKNETENDSKDAEKNRE-----EFEDQSLEKD----SDDKTPDDD 614
           +G++ N++ P +  +  N+  + +  ++ N +     +F+D+S++ D    SD+   +DD
Sbjct: 417 QGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDD 476

Query: 615 P----EQGKSEVGDFK----SEKSNGELSESPGAGKGASGST 648
                +   S  GD        K NG  S+S GA    S ST
Sbjct: 477 ANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDST 518



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 21/88 (23%), Positives = 33/88 (37%), Gaps = 11/88 (12%)

Query: 127 DDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDD-- 184
           D  +SE +  + D  S+  +    D+ +  DS D        D  DS    +     D  
Sbjct: 625 DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSS 684

Query: 185 ---------DASYCTESSFRSHSTYSST 203
                    D+S  +ESS  S S+ S +
Sbjct: 685 NSSDSSDSSDSSNSSESSDSSDSSDSDS 712



 Score = 34.3 bits (77), Expect = 1.9
 Identities = 24/119 (20%), Positives = 44/119 (36%), Gaps = 4/119 (3%)

Query: 534 TEDLTNKARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKDKNETEN----DSKD 589
           + D ++ +  SN S  + +++    S  +   D  N     ++    N +E+    DS D
Sbjct: 650 SSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSD 709

Query: 590 AEKNREEFEDQSLEKDSDDKTPDDDPEQGKSEVGDFKSEKSNGELSESPGAGKGASGST 648
           ++ +       S   DSD     D  +   S      S+ SN   S        +S S+
Sbjct: 710 SDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768



 Score = 33.1 bits (74), Expect = 4.1
 Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 5/93 (5%)

Query: 561 RAKKGDIDNVKSPEETEKDKN-ETENDSK---DAEKNREEFEDQSLEKDSDDKTPDDDPE 616
           ++ +GD  N         D N E++N+S    DA  N +E +D     DS     DD   
Sbjct: 458 KSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDS 517

Query: 617 QGKSEVGDFKSEKSNG-ELSESPGAGKGASGST 648
              +   D     +NG + ++   +GKG S S+
Sbjct: 518 TSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSS 550



 Score = 32.7 bits (73), Expect = 5.4
 Identities = 20/116 (17%), Positives = 44/116 (37%), Gaps = 2/116 (1%)

Query: 534 TEDLTNKARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKDKNETENDSKDAEKN 593
           + D +N +  S+ S   +++        +   D  +    + ++   +   +DS D+  +
Sbjct: 554 SSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDS 613

Query: 594 REEFEDQSLEKDSDDKTPDDDPEQGKSEVGDFKSEKS--NGELSESPGAGKGASGS 647
            +  +    + DS     D      KS+  D  S  S  N + S+S  +   +  S
Sbjct: 614 SDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSS 669



 Score = 32.7 bits (73), Expect = 5.4
 Identities = 18/74 (24%), Positives = 30/74 (40%), Gaps = 1/74 (1%)

Query: 130 ESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDD-DASY 188
           +S    +  D  +  +  +  D+ +  DS+     +     D SD  +     D  D+S 
Sbjct: 825 DSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD 884

Query: 189 CTESSFRSHSTYSS 202
             ESS  S S+ SS
Sbjct: 885 SNESSNSSDSSDSS 898



 Score = 32.3 bits (72), Expect = 7.0
 Identities = 18/71 (25%), Positives = 33/71 (46%)

Query: 577 EKDKNETENDSKDAEKNREEFEDQSLEKDSDDKTPDDDPEQGKSEVGDFKSEKSNGELSE 636
           E   N   +DSK AE +  +    +   DS+    + + +  KS+ G  KS+ S+ + S+
Sbjct: 497 ESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSD 556

Query: 637 SPGAGKGASGS 647
           S  +   +  S
Sbjct: 557 SSNSSDSSDSS 567



 Score = 32.0 bits (71), Expect = 9.2
 Identities = 19/74 (25%), Positives = 31/74 (41%), Gaps = 7/74 (9%)

Query: 127 DDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDY--PEEMED--- 181
           D+   ++E+EE     +      G   +    EDD +  + ++ D  +Y  PE  ED   
Sbjct: 256 DEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHN 315

Query: 182 --DDDDASYCTESS 193
             D D  S   E+S
Sbjct: 316 EVDGDKTSKSEENS 329


>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
            sapiens]
          Length = 722

 Score = 82.8 bits (203), Expect = 5e-15
 Identities = 39/95 (41%), Positives = 56/95 (58%), Gaps = 2/95 (2%)

Query: 2810 LKRVLRSLQAHKMAWPFLEPVDPN--DAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFV 2867
            L+ VL++L  H+ AWPF +PVD    + PDYY +IK PMD+ T+++R++  YY    E +
Sbjct: 67   LRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECI 126

Query: 2868 ADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKL 2902
             D   +F NC  YN         AE LE  F+QK+
Sbjct: 127  QDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKI 161



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 64/246 (26%), Positives = 96/246 (39%), Gaps = 29/246 (11%)

Query: 2656 DLMQLAQATAVAAPCPPVTPAP-PAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKRE 2714
            DL+       V  P P  TP P P  P PPP+P P P   H  +++    P  ++K    
Sbjct: 231  DLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKK---- 286

Query: 2715 EEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGIL 2774
                   K K      TT     +   L      P +     +G    Q     R V   
Sbjct: 287  -----GVKRKADTTTPTTIDPIHEPPSL------PPEPKTTKLG----QRRESSRPVKPP 331

Query: 2775 QSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPN- 2833
            + +     ++  P+  S             K   G+ + + + +    AWPF +PVD   
Sbjct: 332  KKDVPDSQQHPAPEKSSKVSEQL-------KCCSGILKEMFAKKHAAYAWPFYKPVDVEA 384

Query: 2834 -DAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAE 2892
                DY  +IK PMD++T++ +++ R Y    EF AD+  +F NC  YNP D      A 
Sbjct: 385  LGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMAR 444

Query: 2893 VLESFF 2898
             L+  F
Sbjct: 445  KLQDVF 450



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 59/261 (22%), Positives = 97/261 (37%), Gaps = 45/261 (17%)

Query: 1283 SESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLEPLKCELVSGEST 1342
            S S+S+ ++SSD+ S  D SEE+   + +   + EQ +   + +  L   +         
Sbjct: 484  SSSDSSSDSSSDSDSSTDDSEEERAQRLA--ELQEQLKAVHEQLAALSQPQ--------- 532

Query: 1343 GNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNNENRESEK----- 1397
               +++   K  +   KK  + K+ EE   NK S   K K    KK  +N  S       
Sbjct: 533  ---QNKPKKKEKDKKEKKKEKHKRKEEVEENKKS---KAKEPPPKKTKKNNSSNSNVSKK 586

Query: 1398 -----KGQRTSTFQINGKDN-KPKIY------------LKGECLKEISESRVVSGNVEPK 1439
                 K +   T++   +D  KP  Y            L GE L  +     +  + EP 
Sbjct: 587  EPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVH---IIQSREPS 643

Query: 1440 VNNINKIIPENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRD 1499
            + N N    E +I   T+K S +R              +  +E    +  SS  +G    
Sbjct: 644  LKNSNP--DEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSS 701

Query: 1500 SLETLPSTKESDSTQTTTPSA 1520
              E+   +  SDS  + T  A
Sbjct: 702  ESESSSESSSSDSEDSETGPA 722



 Score = 33.9 bits (76), Expect = 2.4
 Identities = 41/167 (24%), Positives = 61/167 (36%), Gaps = 24/167 (14%)

Query: 2217 TATTASTTTTTVSTTAAGTGEQRQSKLS--PQMQV--HQDKTLPP---AQSSSVGPAEAQ 2269
            T T     +T  +TT A T  Q Q+     P +Q   H    + P    Q+  +     Q
Sbjct: 186  TGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQ 245

Query: 2270 PQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQT------------TVSSHVPSEAQPTH 2317
            P    P   PQPQ  P +PA   VQ+ P +   T               +  P+   P H
Sbjct: 246  PLQTPPPVPPQPQ-PPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIH 304

Query: 2318 AQSS---KPQVAAQSQPQSNVQGQSPVRVQSP-SQTRIRPSTPSQLS 2360
               S   +P+     Q + + +   P +   P SQ    P   S++S
Sbjct: 305  EPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVS 351


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 82.8 bits (203), Expect = 5e-15
 Identities = 39/95 (41%), Positives = 56/95 (58%), Gaps = 2/95 (2%)

Query: 2810 LKRVLRSLQAHKMAWPFLEPVDPN--DAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFV 2867
            L+ VL++L  H+ AWPF +PVD    + PDYY +IK PMD+ T+++R++  YY    E +
Sbjct: 67   LRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECI 126

Query: 2868 ADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKL 2902
             D   +F NC  YN         AE LE  F+QK+
Sbjct: 127  QDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKI 161



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 64/246 (26%), Positives = 96/246 (39%), Gaps = 29/246 (11%)

Query: 2656 DLMQLAQATAVAAPCPPVTPAP-PAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKRE 2714
            DL+       V  P P  TP P P  P PPP+P P P   H  +++    P  ++K    
Sbjct: 231  DLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKK---- 286

Query: 2715 EEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGIL 2774
                   K K      TT     +   L      P +     +G    Q     R V   
Sbjct: 287  -----GVKRKADTTTPTTIDPIHEPPSL------PPEPKTTKLG----QRRESSRPVKPP 331

Query: 2775 QSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPN- 2833
            + +     ++  P+  S             K   G+ + + + +    AWPF +PVD   
Sbjct: 332  KKDVPDSQQHPAPEKSSKVSEQL-------KCCSGILKEMFAKKHAAYAWPFYKPVDVEA 384

Query: 2834 -DAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAE 2892
                DY  +IK PMD++T++ +++ R Y    EF AD+  +F NC  YNP D      A 
Sbjct: 385  LGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMAR 444

Query: 2893 VLESFF 2898
             L+  F
Sbjct: 445  KLQDVF 450



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 101/461 (21%), Positives = 167/461 (36%), Gaps = 69/461 (14%)

Query: 2235 TGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQ 2294
            T  Q Q  L    +V     L P+      P    P    PS Q Q Q QP  P  P+ Q
Sbjct: 924  TSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQ 983

Query: 2295 TQPEVQTQ----------TTVSSHV-----PSEAQPTH-AQSSKPQVAAQSQPQSNVQGQ 2338
              P+ Q Q             S+H+     P   QP H     +P     ++PQ  +Q  
Sbjct: 984  PPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHH 1043

Query: 2339 SPVR-----VQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIP---IQPHTSLQIPSQGQ 2390
               R       S    R  PS P  +   Q SQ Q+ T Q  P   +QP    ++ +   
Sbjct: 1044 HSPRHHKSDPYSTGHLREAPS-PLMIHSPQMSQFQSLTHQSPPQQNVQPKKQ-ELRAASV 1101

Query: 2391 PQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQ-PQVIAVP-QLQQQVQVLSQI 2448
             Q QP V    + + S      +  S P  P L+ + P+ P+ I  P  L Q+ ++    
Sbjct: 1102 VQPQPLVVVKEEKIHS-----PIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVD 1156

Query: 2449 QSQVVAQ---------------IQAQQSGVPQQIKLQLPIQIQQS--SAVQTHQIQNVVT 2491
              + V +                Q Q+   P   K  L I+   S  S VQ H      T
Sbjct: 1157 VGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSST 1216

Query: 2492 VQAASVQ-EQLQRVQQLRDQQQK--KKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVI 2548
             +++S   EQ +R  + +++++K  K Q +   K +  L+         +  + +     
Sbjct: 1217 AKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAH 1276

Query: 2549 EHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNA 2608
            E  ++++     +R+E Q+                ++++QAA          Q    Q+ 
Sbjct: 1277 EEARRRQEQQQQQRQEQQQ----------------QQQQQAAAVAAAATPQAQSSQPQSM 1320

Query: 2609 TKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDL 2649
                  L + +EQ R       A +D + Q ++    + +L
Sbjct: 1321 LDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENL 1361



 Score = 55.8 bits (133), Expect = 6e-07
 Identities = 82/317 (25%), Positives = 117/317 (36%), Gaps = 46/317 (14%)

Query: 2279 PQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQ 2338
            PQP+  P  P  PE  T P +     VS      A P   Q S+P   A + P      +
Sbjct: 831  PQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALP--QQPSRPSNRAAALPPK--PAR 886

Query: 2339 SPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQ 2398
             P    + +QT + P  P      Q  QV     +P P  P TS+Q+  Q   Q   +VQ
Sbjct: 887  PPAVSPALTQTPLLPQPPM----AQPPQVLLEDEEP-PAPPLTSMQM--QLYLQQLQKVQ 939

Query: 2399 SSTQTLSSGQTLNQVTVSSPSRPQLQIQQ---------PQPQVIAVPQLQQQ-------- 2441
              T  L S +  +Q     P  P   +QQ         P PQ    PQ Q Q        
Sbjct: 940  PPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHL 999

Query: 2442 --VQVLSQIQSQVVAQIQ-------AQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTV 2492
              +Q  + IQ     Q Q        QQ   PQ  K Q  IQ   S         +   +
Sbjct: 1000 QPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHL 1059

Query: 2493 QAASVQEQLQRVQQLRDQ---QQKKKQQQIEIKREHTLQASNQSEIIQKQ--VVMKHNAV 2547
            + A     +   Q  + Q    Q   QQ ++ K++    AS    ++Q Q  VV+K   +
Sbjct: 1060 REAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAAS----VVQPQPLVVVKEEKI 1115

Query: 2548 IEHLKQKKSMTPAEREE 2564
               + + +  +P+ R E
Sbjct: 1116 HSPIIRSEPFSPSLRPE 1132



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 96/460 (20%), Positives = 165/460 (35%), Gaps = 77/460 (16%)

Query: 2257 PAQSSSVGPAEAQ-PQTAQPSAQPQPQT---QPQSPAQP--------EVQTQPEVQTQTT 2304
            PA+  +V PA  Q P   QP     PQ      + PA P         +Q   +VQ  T 
Sbjct: 884  PARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTP 943

Query: 2305 VSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIR-PSTPSQLSPGQ 2363
            +   V  ++QP       P  + Q Q Q       P + Q P Q + + P  P  L P  
Sbjct: 944  LLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQP-- 1001

Query: 2364 QSQVQTTTSQPIPIQ----PHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPS 2419
              Q  T   QP P Q    PH     P  GQ    PQ     Q +    +         S
Sbjct: 1002 -MQFSTHIQQPPPPQGQQPPH-----PPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYS 1055

Query: 2420 RPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQ-- 2477
               L+ + P P +I  PQ+ Q   +  Q   Q   Q + Q+      ++ Q  + +++  
Sbjct: 1056 TGHLR-EAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEK 1114

Query: 2478 --SSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKR------------ 2523
              S  +++      +  +     E ++    L    Q+ + + +++ R            
Sbjct: 1115 IHSPIIRSEPFSPSLRPEPPKHPESIKAPVHL---PQRPEMKPVDVGRPVIRPPEQNAPP 1171

Query: 2524 ------EHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKY 2577
                  +   Q        +K + +K+      L QK   TP+   ++            
Sbjct: 1172 PGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSS---------- 1221

Query: 2578 ILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLD--- 2634
              D  ++  + A +K +RE++++ +              K KE+LR E ++ R   D   
Sbjct: 1222 --DSFEQFRRAAREKEEREKALKAQAEHAE---------KEKERLRQERMRSREDEDALE 1270

Query: 2635 --KDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPP 2672
              +    E +   ++  + ++E+   Q  QA AVAA   P
Sbjct: 1271 QARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATP 1310



 Score = 42.7 bits (99), Expect = 0.005
 Identities = 120/606 (19%), Positives = 211/606 (34%), Gaps = 135/606 (22%)

Query: 2217 TATTASTTTTTVSTTAAGTGEQRQSKLS--PQMQV--HQDKTLPP---AQSSSVGPAEAQ 2269
            T T     +T  +TT A T  Q Q+     P +Q   H    + P    Q+  +     Q
Sbjct: 186  TGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQ 245

Query: 2270 PQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQT------------TVSSHVPSEAQPTH 2317
            P    P   PQPQ  P +PA   VQ+ P +   T               +  P+   P H
Sbjct: 246  PLQTPPPVPPQPQ-PPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIH 304

Query: 2318 AQSS---KPQVAAQSQPQSNVQGQSPVRVQSP-SQTRIRPSTPSQLSPGQQSQVQTTTSQ 2373
               S   +P+     Q + + +   P +   P SQ    P   S++S  +Q +  +   +
Sbjct: 305  EPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVS--EQLKCCSGILK 362

Query: 2374 PIPIQPHTSLQIPSQGQPQSQP-QVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQ----- 2427
             +  + H +   P       +   +      +     ++ +     +R     Q+     
Sbjct: 363  EMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADV 422

Query: 2428 ------------PQPQVIAVPQLQQQV------QVLSQIQSQVVAQIQAQQSGVPQQIKL 2469
                        P  +V+A+ +  Q V      ++  + +  VVA        VP   K+
Sbjct: 423  RLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVA---VSSPAVPPPTKV 479

Query: 2470 QLPIQIQQSSA-------VQTHQIQNVVTVQAASVQEQLQRVQQ----LRDQQQKKKQQQ 2518
              P     SS+         T   +     + A +QEQL+ V +    L   QQ K +++
Sbjct: 480  VAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKK 539

Query: 2519 IEIKREHTLQASNQSEIIQK-----------QVVMKHNAVIEHLKQK-----KSMTP--- 2559
             + K+E   +   + E +++           +   K+N+   ++ +K     KS  P   
Sbjct: 540  EKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTY 599

Query: 2560 -AEREENQRMIVCNQVMKYILD-------------------------------KIDKEEK 2587
             +E E+  + +   +  +  LD                               +ID E  
Sbjct: 600  ESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETL 659

Query: 2588 QAAKKRKREESVE---QKRSKQNATKLSALLFKHK----EQLRAEILKKRALLD-KDLQI 2639
            + +  R+ E  V    +K+ K  A K+  +    K        +E   + +  D +D + 
Sbjct: 660  KPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSET 719

Query: 2640 EVQEELK------RDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAP------PPSP 2687
            E+  + K      R+ K        Q+ QA A     PP  P  P PP P      PP P
Sbjct: 720  EMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPP 779

Query: 2688 PPPPAV 2693
            PPPP++
Sbjct: 780  PPPPSM 785



 Score = 36.6 bits (83), Expect = 0.37
 Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 11/57 (19%)

Query: 2650 KIKKEKDLMQLAQATAVAAPCPPVTPAPP-----------APPAPPPSPPPPPAVQH 2695
            +++K +    L  +  V +  PP  P PP            PP PPP P PPP  QH
Sbjct: 934  QLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQH 990



 Score = 35.8 bits (81), Expect = 0.64
 Identities = 13/25 (52%), Positives = 16/25 (64%)

Query: 8   PPKQPAAPAAERCAPAPPPPPPPPT 32
           PP+QP  P   +    PPPPPPPP+
Sbjct: 760 PPQQPPPPPPPQQQQQPPPPPPPPS 784



 Score = 35.0 bits (79), Expect = 1.1
 Identities = 59/261 (22%), Positives = 97/261 (37%), Gaps = 45/261 (17%)

Query: 1283 SESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLEPLKCELVSGEST 1342
            S S+S+ ++SSD+ S  D SEE+   + +   + EQ +   + +  L   +         
Sbjct: 484  SSSDSSSDSSSDSDSSTDDSEEERAQRLA--ELQEQLKAVHEQLAALSQPQ--------- 532

Query: 1343 GNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNNENRESEK----- 1397
               +++   K  +   KK  + K+ EE   NK S   K K    KK  +N  S       
Sbjct: 533  ---QNKPKKKEKDKKEKKKEKHKRKEEVEENKKS---KAKEPPPKKTKKNNSSNSNVSKK 586

Query: 1398 -----KGQRTSTFQINGKDN-KPKIY------------LKGECLKEISESRVVSGNVEPK 1439
                 K +   T++   +D  KP  Y            L GE L  +     +  + EP 
Sbjct: 587  EPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVH---IIQSREPS 643

Query: 1440 VNNINKIIPENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRD 1499
            + N N    E +I   T+K S +R              +  +E    +  SS  +G    
Sbjct: 644  LKNSNP--DEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSS 701

Query: 1500 SLETLPSTKESDSTQTTTPSA 1520
              E+   +  SDS  + T  A
Sbjct: 702  ESESSSESSSSDSEDSETEMA 722



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 19/87 (21%)

Query: 8    PPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSP 67
            P   P  P+ ++     PPPPPPP   P                   Q +  P+     P
Sbjct: 957  PLPPPPHPSVQQQLQQQPPPPPPPQPQPP---------------PQQQHQPPPRPVHLQP 1001

Query: 68   RGGSSSRRKPPPP----PPAPPSTSAP 90
               S+  ++PPPP    PP PP    P
Sbjct: 1002 MQFSTHIQQPPPPQGQQPPHPPPGQQP 1028



 Score = 33.1 bits (74), Expect = 4.1
 Identities = 15/38 (39%), Positives = 17/38 (44%)

Query: 2668 APCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLP 2705
            AP P     PP P  PPP PPP    Q       P++P
Sbjct: 749  APAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMP 786



 Score = 32.0 bits (71), Expect = 9.2
 Identities = 15/33 (45%), Positives = 17/33 (51%), Gaps = 6/33 (18%)

Query: 9   PKQPAAPAAERCAPAPP------PPPPPPTSGP 35
           P+QP  P  +   P PP      PPPPPP S P
Sbjct: 754 PQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMP 786



 Score = 32.0 bits (71), Expect = 9.2
 Identities = 24/81 (29%), Positives = 30/81 (37%), Gaps = 7/81 (8%)

Query: 8    PPKQPAAPAAERCAPAPPPPP---PPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRL 64
            PP  P+     +  P PPPPP   PPP        R  H    +      Q       + 
Sbjct: 960  PPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQP 1019

Query: 65   SSPRGGSSSRRKPPPPPPAPP 85
              P  G    ++PPPP PA P
Sbjct: 1020 PHPPPG----QQPPPPQPAKP 1036


>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
            [Homo sapiens]
          Length = 1050

 Score = 82.4 bits (202), Expect = 6e-15
 Identities = 66/222 (29%), Positives = 98/222 (44%), Gaps = 29/222 (13%)

Query: 2702 PTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDR 2761
            P L   +    + E  D S KS     +  T KE   +     +C+   +     + C++
Sbjct: 790  PGLHQDNSSNGKSEWLDPSQKSPLH--VGETRKEDDPNEDWCAVCQNGGE----LLCCEK 843

Query: 2762 CQNWYHGRC-VGILQSEAELIDEYVCPQCQ-----------------STEDAMTVLTPLT 2803
            C   +H  C V  L +      E++C  C+                 S +     L  LT
Sbjct: 844  CPKVFHLSCHVPTLTNFPS--GEWICTFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKLT 901

Query: 2804 EKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRY--YE 2861
              D    +R+L  L  H+M+  F +PV P   PDYY +IK PMDL+T+++R+Q  Y  Y 
Sbjct: 902  PIDKRKCERLLLFLYCHEMSLAFQDPV-PLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYS 960

Query: 2862 KLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLK 2903
            K  +FVAD   IF NC  +N  DS        LE++F + LK
Sbjct: 961  KPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLK 1002



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 34/90 (37%), Positives = 42/90 (46%), Gaps = 6/90 (6%)

Query: 390 DDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVT-DCVA- 447
           +D C VC   G+LLCCE C  V+HL C  P L   P  EW C  C     P V  DC A 
Sbjct: 826 EDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAP 885

Query: 448 ----EIQKNKPYIRHEPIGYDRSRRKYWFL 473
               E +K +  ++  PI   +  R   FL
Sbjct: 886 SHNSEKKKTEGLVKLTPIDKRKCERLLLFL 915


>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
            [Homo sapiens]
          Length = 1016

 Score = 82.4 bits (202), Expect = 6e-15
 Identities = 66/222 (29%), Positives = 98/222 (44%), Gaps = 29/222 (13%)

Query: 2702 PTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDR 2761
            P L   +    + E  D S KS     +  T KE   +     +C+   +     + C++
Sbjct: 756  PGLHQDNSSNGKSEWLDPSQKSPLH--VGETRKEDDPNEDWCAVCQNGGE----LLCCEK 809

Query: 2762 CQNWYHGRC-VGILQSEAELIDEYVCPQCQ-----------------STEDAMTVLTPLT 2803
            C   +H  C V  L +      E++C  C+                 S +     L  LT
Sbjct: 810  CPKVFHLSCHVPTLTNFPS--GEWICTFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKLT 867

Query: 2804 EKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRY--YE 2861
              D    +R+L  L  H+M+  F +PV P   PDYY +IK PMDL+T+++R+Q  Y  Y 
Sbjct: 868  PIDKRKCERLLLFLYCHEMSLAFQDPV-PLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYS 926

Query: 2862 KLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLK 2903
            K  +FVAD   IF NC  +N  DS        LE++F + LK
Sbjct: 927  KPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLK 968



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 34/90 (37%), Positives = 42/90 (46%), Gaps = 6/90 (6%)

Query: 390 DDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVT-DCVA- 447
           +D C VC   G+LLCCE C  V+HL C  P L   P  EW C  C     P V  DC A 
Sbjct: 792 EDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAP 851

Query: 448 ----EIQKNKPYIRHEPIGYDRSRRKYWFL 473
               E +K +  ++  PI   +  R   FL
Sbjct: 852 SHNSEKKKTEGLVKLTPIDKRKCERLLLFL 881


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 82.0 bits (201), Expect = 8e-15
 Identities = 213/957 (22%), Positives = 337/957 (35%), Gaps = 109/957 (11%)

Query: 1483 TKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSEVK 1542
            T S    SS  E  +  ++ T  +T    +    TPS++   +++       ++ T+   
Sbjct: 3199 TMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTT------KVLTTTTT 3252

Query: 1543 KVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVITE--VTTMTSTVATESK 1600
              T++P +S   +     +I     P  +   V   S   T  T   +TT T+TVAT S 
Sbjct: 3253 GFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSM 3312

Query: 1601 TVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTT 1660
                       T  S T +      TT TT    LS PS+  +V        S T+ TT 
Sbjct: 3313 AT-----PSSSTQTSGTTHTPPVPNTTATTHGRSLS-PSSPHTVRTAWTSATSGTLGTTH 3366

Query: 1661 VTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKT--RSGTALPSYRKFV------ 1712
            +T+  T T  T   + T + ++ST         SR  ++    GT  P + +        
Sbjct: 3367 ITEPSTGTSHTPAAT-TGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTAT 3425

Query: 1713 -TKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIW---PYPSPRPTFGITWR 1768
             T S  ++  +LP+           I  V       + A   W    YP P P+ G    
Sbjct: 3426 ATPSKTRTSTLLPSSPTS-----APITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDT 3480

Query: 1769 YRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRT-ETSETEITTTEIIKRRD- 1826
            Y    +++ AG ++  + L    R     A+A PG       +  E  +    + + R+ 
Sbjct: 3481 Y--SNIRA-AGGAVCEQPLGLECR-----AQAQPGVPLRELGQVVECSLDFGLVCRNREQ 3532

Query: 1827 VGPYGIRSEYCIRKIICPIG-VPETP--KETPTPQRKGLRSSALRPKRPE--TPKQTGPV 1881
            VG + +   Y IR   C  G  P TP    T TP      +  L  +     T   TG  
Sbjct: 3533 VGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGST 3592

Query: 1882 IIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTT- 1940
             I +           + + A       ++A    +  R     P + +T+T S  +S T 
Sbjct: 3593 AIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSP-RTATTLPVLTSTATKSTATSFTP 3651

Query: 1941 ---------------STISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFH 1985
                           +T   A    + P S   TT T  VLTTK  +    T   +    
Sbjct: 3652 IPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKA-TTTRATSSMSTPSS 3710

Query: 1986 QTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRT-ATVTIRPNTSGSGG 2044
                TW+    + +              S+ GT   T+   +P T ATVT+    +GS  
Sbjct: 3711 TPGTTWILTELTTAATTTAATGPTATPSSTPGT---TWILTEPSTTATVTV---PTGSTA 3764

Query: 2045 TTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVST 2104
            T S+++   G  ++   +   TP   S+       TP      A      +     P +T
Sbjct: 3765 TASSTRATAGT-LKVLTSTATTPTVISSRA-----TPSSSPGTATALPALRSTATTPTAT 3818

Query: 2105 AVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQG 2164
            +V+A  + S       L+  T+ +   S+A+    P+       +   T  T+  G +  
Sbjct: 3819 SVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATG-SVA 3877

Query: 2165 LTVVIQGQGQTTGQLQLIPQGVTVLPG--PGQQLMQ----AAMPNGTVQRFLFTPLATTA 2218
                  G   TT        G T  P   PG  L      +     T +    TP +   
Sbjct: 3878 TPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPG 3937

Query: 2219 TTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQ 2278
            TT + T  T +TT   TG       S   Q       PP  +++   A    ++  PS+ 
Sbjct: 3938 TTHTATVLTTTTTTVATGSMATP--SSSTQTSGTTHTPPVPNTT---ATTHGRSLPPSS- 3991

Query: 2279 PQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQ 2338
            P       + A   +     +   +TV+SH P+    T  Q S P   A S P  +    
Sbjct: 3992 PHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTST-TQHSTP---ALSSPHPS---- 4043

Query: 2339 SPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQP 2395
                    S+T   P +P   +PG       TT+   P +  TS  +PS   P S P
Sbjct: 4044 --------SRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPS--SPTSAP 4090



 Score = 69.7 bits (169), Expect = 4e-11
 Identities = 196/924 (21%), Positives = 315/924 (34%), Gaps = 142/924 (15%)

Query: 1483 TKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSEVK 1542
            T S    SS  E  +  ++ T  +T    +    TPS++   +++       ++ T+   
Sbjct: 4346 TMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTT------KVPTTTTT 4399

Query: 1543 KVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVITE--VTTMTSTVATESK 1600
              T +P +S   +     +I     P      V   S   T  T   +TT T+TVAT S 
Sbjct: 4400 GFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSM 4459

Query: 1601 TVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTT 1660
                       T  S T +      TT TT    LS PS+  +V        S T+ TT 
Sbjct: 4460 AT-----PSSSTQTSGTTHTPPVPNTTATTHGRSLS-PSSPHTVRTAWTSATSGTLGTTH 4513

Query: 1661 VTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKT--RSGTALPSYRKFVTKSSKK 1718
            +T+  T T  T   + T + ++ST         SR  ++    GT  P +    T +S+ 
Sbjct: 4514 ITEPSTGTSHTPAAT-TGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGH---TTATSRT 4569

Query: 1719 SIFVLPNDD-----LKKLARKGGIREVPYFNYNAKPALDIW---PYPSPRPTFGITWRYR 1770
            +    P+       L        I  V       + A   W    YP P P+ G    Y 
Sbjct: 4570 TATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTY- 4628

Query: 1771 LQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRT-ETSETEITTTEIIKRRD-VG 1828
               +++ AG ++  + L    R     A+A PG       +  E  +    + + R+ VG
Sbjct: 4629 -SNIRA-AGGAVCEQPLGLECR-----AQAQPGVPLGELGQVVECSLDFGLVCRNREQVG 4681

Query: 1829 PYGIRSEYCIRKIICPIG-VPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWV 1887
             + +   Y IR   C  G  P TP  +         S+A+    P T          TW+
Sbjct: 4682 KFKMCFNYEIRVFCCNYGHCPSTPATS---------STAMPSSTPGT----------TWI 4722

Query: 1888 AEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQ 1947
              E                                       T+T + T+ST ST +P+ 
Sbjct: 4723 LTE--------------------------------------LTTTATTTASTGSTATPSS 4744

Query: 1948 --------KVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNS 1999
                    KV+ +P +    T +K    T   SP T T         T +T      S +
Sbjct: 4745 TPGTAPPPKVLTSPATTPTATSSK---ATSSSSPRTATTLPVLTSTATKST----ATSVT 4797

Query: 2000 GVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNT--SGSGGTTSNSQVITGPQI 2057
             +        G +P  T T   T ++  P +   T   +T  +    TT  +   + P  
Sbjct: 4798 PIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSS 4857

Query: 2058 RPGMTVIRTPL-QQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTP 2116
             PG T I T L   +T   A   T           ++T++      + +  +  T SSTP
Sbjct: 4858 TPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTP 4917

Query: 2117 GQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQG--HGGNQGLTVVIQGQGQ 2174
            G   + +  ST+   ++ + P            A  TQ T G  H      T  +     
Sbjct: 4918 GTTWILTEPSTT---ATVTVPTG------STATASSTQATAGTPHVSTTATTPTVTSSKA 4968

Query: 2175 TTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTP---LATTATTASTTTTTVSTT 2231
            T       P   T LP      +++     T   F   P   L TT T  S TTT  +T 
Sbjct: 4969 TPSS---SPGTATALPA-----LRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATM 5020

Query: 2232 AAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQ----TQPQS 2287
            +  T       +     +    T   A + SV    + P TA  +  P       T   S
Sbjct: 5021 STATPSSTPETVHTSTVLTATATTTGA-TGSVATPSSTPGTAHTTKVPTTTTTGFTATPS 5079

Query: 2288 PAQPEVQTQPEVQTQTTVSS-HVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSP 2346
             +     T P     +T+S+ H  S  + TH  +     A  ++  ++    S     + 
Sbjct: 5080 SSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTR 5139

Query: 2347 SQTRIRPSTPSQLSPGQQSQVQTT 2370
              T +  +  +  + G  + + +T
Sbjct: 5140 ILTELTTTATTTAATGSTATLSST 5163



 Score = 60.8 bits (146), Expect = 2e-08
 Identities = 99/422 (23%), Positives = 143/422 (33%), Gaps = 62/422 (14%)

Query: 2010 GIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRT-PL 2068
            G  PS+  TS     S  P T  +     T+ +  TT ++     P   PG T I T P 
Sbjct: 3050 GHCPSTPATSSTAMPSSTPGTTWILTELTTTAT--TTESTGSTATPSSTPGTTWILTEPS 3107

Query: 2069 QQSTL----GKAIIRTPVMVQPGAPQQVMTQII------RGQPVS-----TAVSAPNTVS 2113
              +T+    G     +      G P    T         +  P S     TA+ A  + +
Sbjct: 3108 TTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTA 3167

Query: 2114 STPGQKSLT--------------SATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGH 2159
            +TP   S T              S T+T     S + P    +     T+   T  T G 
Sbjct: 3168 TTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGA 3227

Query: 2160 GGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPG--PGQQ----LMQAAMPNGTVQRFLFTP 2213
             G+        G   TT  L     G T  P   PG      +  +     T +    TP
Sbjct: 3228 TGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTP 3287

Query: 2214 LATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTA 2273
             +   TT + T  T +TT   TG       S   Q       PP  +++   A    ++ 
Sbjct: 3288 SSIPGTTHTPTVLTTTTTTVATGSMATP--SSSTQTSGTTHTPPVPNTT---ATTHGRSL 3342

Query: 2274 QPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQS 2333
             PS+    +T   S     + T   +   +T +SH P+    T  Q S P   A S P  
Sbjct: 3343 SPSSPHTVRTAWTSATSGTLGTT-HITEPSTGTSHTPAATTGT-TQHSTP---ALSSPHP 3397

Query: 2334 NVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQS 2393
            +            S+T   P +P   +PG       TT+   P +  TS  +PS   P S
Sbjct: 3398 S------------SRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPS--SPTS 3443

Query: 2394 QP 2395
             P
Sbjct: 3444 AP 3445



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 106/472 (22%), Positives = 156/472 (33%), Gaps = 80/472 (16%)

Query: 1925 PTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNF 1984
            P+  ATS+T+  SST  T     K+         TT T    T   GS AT +       
Sbjct: 4200 PSTPATSSTATPSSTPGTTWILTKL--------TTTATT---TESTGSTATPSSTPG--- 4245

Query: 1985 HQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTS-GSG 2043
                 TW+    S +  V V         S+  T+     S    T TVT    T   S 
Sbjct: 4246 ----TTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSP 4301

Query: 2044 GTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVS 2103
            GT +    +      P  T   T +  S+LG    R      P A     T         
Sbjct: 4302 GTATALPALRSTATTPTATSF-TAIPSSSLGTTWTRLSQTTTPTATMSTAT--------- 4351

Query: 2104 TAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQ 2163
                 P++   T    ++ + T+T+   + +   P    G    T    T  T       
Sbjct: 4352 -----PSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTT------- 4399

Query: 2164 GLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTAST 2223
            G TV       T     +     T     G  +  +++P  T    + T   TT  T S 
Sbjct: 4400 GFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSM 4459

Query: 2224 TTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQT 2283
             T + ST  +GT                    PP  +++   A    ++  PS+    +T
Sbjct: 4460 ATPSSSTQTSGTTHT-----------------PPVPNTT---ATTHGRSLSPSSPHTVRT 4499

Query: 2284 QPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRV 2343
               S     + T   +   +T +SH P+    T  Q S P   A S P  +         
Sbjct: 4500 AWTSATSGTLGTT-HITEPSTGTSHTPAATTGT-TQHSTP---ALSSPHPS--------- 4545

Query: 2344 QSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQP 2395
               S+T   P +P   +PG  +    TT+   P +  TS  +PS   P S P
Sbjct: 4546 ---SRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPS--SPTSAP 4592



 Score = 59.3 bits (142), Expect = 5e-08
 Identities = 90/395 (22%), Positives = 136/395 (34%), Gaps = 42/395 (10%)

Query: 2013 PSSTGTSQQTFTSFQPRTATVTIRPNTSGS-----GGT-TSNSQVITGPQIRPGMTVIRT 2066
            PS+  TS     S  P T  +  +P T+ +     G T T  S + T P  +   T   T
Sbjct: 2579 PSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATT 2638

Query: 2067 PLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATS 2126
            P   S+       TP      A      +     P +T+V+   + S       L+  T+
Sbjct: 2639 PTVTSSKA-----TPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTT 2693

Query: 2127 TSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGV 2186
             +   S+A+    P+      T+   T  T G  G+        G   TT        G 
Sbjct: 2694 PTATMSTATPSSTPETAHTS-TVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGF 2752

Query: 2187 TVLPG--PGQQLMQ----AAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQ 2240
            T  P   PG  L      +     T +    TP +   TT + T  T +TT   TG    
Sbjct: 2753 TATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMAT 2812

Query: 2241 SKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQ 2300
               S Q       T  P   +++     +   + P + P       + A   +     + 
Sbjct: 2813 PSSSTQTS---GTTHTPPVPNTMATTHGR---SLPPSSPHTVRTAWTSATSGILGTTHIT 2866

Query: 2301 TQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLS 2360
              +TV+SH  +    T  Q S P   A S P  +            S+T   P +P   +
Sbjct: 2867 EPSTVTSHTLAATTGT-TQHSTP---ALSSPHPS------------SRTTESPPSPGTTT 2910

Query: 2361 PGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQP 2395
            PG  +    TT+   P +  TS  +PS   P S P
Sbjct: 2911 PGHTTATSRTTATATPSKTRTSTLLPS--SPTSAP 2943



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 187/977 (19%), Positives = 325/977 (33%), Gaps = 134/977 (13%)

Query: 1480 SSETKSHLLSSSDAEGNYRDSLETLPS-TKESDSTQTTTPSASCPESNSVNQVEDMEIET 1538
            S+ TKS   S +        +  TLP  T    +T +T   +S PE+   + V   +  T
Sbjct: 3639 STATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATT 3698

Query: 1539 SEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKT--VITEV-TTMTSTV 1595
            +      S+P ++   + +  +                  S   T  ++TE  TT T TV
Sbjct: 3699 TRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTV 3758

Query: 1596 ATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPST--GGSVDIISVKEQS 1653
             T S       +    T+   T      +  TT T ++  +TPS+  G +  + +++  +
Sbjct: 3759 PTGSTATASSTRATAGTLKVLT------STATTPTVISSRATPSSSPGTATALPALRSTA 3812

Query: 1654 KTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVT 1713
             T   T+VT   +++ GT  T ++      T      M  + P  T       +     T
Sbjct: 3813 TTPTATSVTAIPSSSLGTAWTRLS-----QTTTPTATMSTATPSSTPETVHTSTVLTTTT 3867

Query: 1714 KSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQT 1773
             +++ +  V         A    +       + A P        S  P   +T    + T
Sbjct: 3868 TTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATP--------SSSPGTALTPPVWIST 3919

Query: 1774 VKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIR 1833
              +             + R   +   + PG  TT T T  T  TTT       V    + 
Sbjct: 3920 TTT------------PTTRGSTVTPSSIPG--TTHTATVLTTTTTT-------VATGSMA 3958

Query: 1834 SEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELE 1893
            +     +       P  P  T T   + L  S+    R      T  ++  T + E    
Sbjct: 3959 TPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTV 4018

Query: 1894 LWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATST---TSPTSSTTSTISPAQKVM 1950
                 A      +    A+          + P    T+T   T  TS TT+T +P++   
Sbjct: 4019 TSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSK--- 4075

Query: 1951 VAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLG 2010
                    T  + ++ ++   +P T            ++ W+                  
Sbjct: 4076 --------TRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYP------------- 4114

Query: 2011 IIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQ 2070
             +P  +G    T+++ +     V  +P      G    +Q   G  +R    V+   L  
Sbjct: 4115 -MPGPSGGDFDTYSNIRAAGGAVCEQPL-----GLECRAQAQPGVPLRELGQVVECSLDF 4168

Query: 2071 STLGKAIIRTPVMVQPGAPQQVMTQIIR-------GQPVSTAVSAPNTVSSTPGQ----- 2118
              + +         Q G  +      IR         P + A S+  T SSTPG      
Sbjct: 4169 GLVCRN------REQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILT 4222

Query: 2119 KSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQ 2178
            K  T+AT+T +  S+A+    P    +    +    +T   G     T        T G 
Sbjct: 4223 KLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGS----TATASSTQATAGT 4278

Query: 2179 LQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTT-TTVSTTAAGTGE 2237
                P   T    P     +A   +          L +TATT + T+ T + +++ GT  
Sbjct: 4279 ----PHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTW 4334

Query: 2238 QRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSA-------QPQPQTQPQSPAQ 2290
             R S+           T P A  S+  P+   P+TA  S          +      +P+ 
Sbjct: 4335 TRLSQT----------TTPTATMSTATPSST-PETAHTSTVLTTTATTTRATGSVATPSS 4383

Query: 2291 -PEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQT 2349
             P      +V T TT    V   + P  A++    ++  + P ++    +P  V   + T
Sbjct: 4384 TPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHT 4443

Query: 2350 -------RIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQ 2402
                       +T S  +P   +Q   TT  P P+ P+T+     +    S P    +  
Sbjct: 4444 PTVLTTTTTTVATGSMATPSSSTQTSGTTHTP-PV-PNTTATTHGRSLSPSSPHTVRTAW 4501

Query: 2403 TLSSGQTLNQVTVSSPS 2419
            T ++  TL    ++ PS
Sbjct: 4502 TSATSGTLGTTHITEPS 4518



 Score = 54.3 bits (129), Expect = 2e-06
 Identities = 174/803 (21%), Positives = 272/803 (33%), Gaps = 114/803 (14%)

Query: 1483 TKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSEVK 1542
            T S    SS  E  +  ++ T  +T    +    TPS++   +++       ++ T+   
Sbjct: 2697 TMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTT------KVPTTTTT 2750

Query: 1543 KVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTV--ITEVTTMTSTVATESK 1600
              T++P +S   +     +I     P  +   V   S   T    T +TT T+TVAT   
Sbjct: 2751 GFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVAT--- 2807

Query: 1601 TVIKVEKGDKQTVVSSTENCAKSTV----TTTTTTVTKLSTPSTGGSVDIISVKEQSKTV 1656
                   G   T  SST+    +       T  TT  +   PS+  +V        S  +
Sbjct: 2808 -------GSMATPSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGIL 2860

Query: 1657 VTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKT--RSGTALPSYRKFVTK 1714
             TT +T+  T T  TL  + T + ++ST         SR  ++    GT  P +    T 
Sbjct: 2861 GTTHITEPSTVTSHTLAAT-TGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGH---TTA 2916

Query: 1715 SSKKSIFVLPNDD-----LKKLARKGGIREVPYFNYNAKPALDIW---PYPSPRPTFGIT 1766
            +S+ +    P+       L        I  V       + A   W    YP P P+ G  
Sbjct: 2917 TSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDF 2976

Query: 1767 WRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRT-ETSETEITTTEIIKRR 1825
              Y    +++ AG ++  + L    R     A+A PG       +  E  +    + + R
Sbjct: 2977 DTY--SNIRA-AGGAVCEQPLGLECR-----AQAQPGVPLRELGQVVECSLDFGLVCRNR 3028

Query: 1826 D-VGPYGIRSEYCIRKIICPIG-VPETPKETPTPQRKG----------LRSSALRPKRPE 1873
            + VG + +   Y IR   C  G  P TP  + T               L ++A   +   
Sbjct: 3029 EQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTG 3088

Query: 1874 TPKQTGPVIIETWVAEEELELWEIRA-FAERVEKEKAQAVEQQAKKRLEQQKPTVIA--- 1929
            +          TW+  E      +             QA             PTV +   
Sbjct: 3089 STATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKA 3148

Query: 1930 -------TSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNK 1982
                   T+T  P   +T+T   A      P S   TT T++  TT     AT++     
Sbjct: 3149 TPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTT--PTATMSTATPS 3206

Query: 1983 NFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFT-SFQPRTATVTIRPNTSG 2041
            +  +T  T                 VL    ++TG +    T S  P TA  T    T+ 
Sbjct: 3207 STPETVHT---------------STVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTT 3251

Query: 2042 SGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQP 2101
            +G T +       P   PG T    P+  ST      R   +     P    T  +    
Sbjct: 3252 TGFTAT-------PSSSPG-TARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTT 3303

Query: 2102 VSTAVSAPNTVSSTPGQKSLTSAT-----STSNIQSSASQPPRPQQGQVKLTMAQLTQLT 2156
             +T  +      S+  Q S T+ T     +T+     +  P  P   +   T A     T
Sbjct: 3304 TTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSA-----T 3358

Query: 2157 QGHGGNQGLTVVIQGQGQ----TTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFT 2212
             G  G   +T    G       TTG  Q     ++  P P  +  ++    GT      T
Sbjct: 3359 SGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALS-SPHPSSRTTESPPSPGTT-----T 3412

Query: 2213 PLATTATTASTTTTTVSTTAAGT 2235
            P  T AT+ +T T T S T   T
Sbjct: 3413 PGHTRATSRTTATATPSKTRTST 3435



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 121/586 (20%), Positives = 189/586 (32%), Gaps = 97/586 (16%)

Query: 1505 PSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNL--SNDFI 1562
            P    S +T  T  S+    S+S      + + TS   K T++ +T    S L  +    
Sbjct: 4752 PKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLP 4811

Query: 1563 DENGLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENCAK 1622
            ++   P+     ++  S  +T  T     T    T + +          T    TE    
Sbjct: 4812 EQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTE---L 4868

Query: 1623 STVTTTTTTVTKLSTPS-TGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKE 1681
            +T  TTT      +TPS T G+  I++  E + T  TT  T S  T   T  T+  +++ 
Sbjct: 4869 TTAATTTAATGPTATPSSTPGTTWILT--ELTTTATTTASTGSTATPSSTPGTTWILTEP 4926

Query: 1682 YSTRD-KVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREV 1740
             +T    V     +    T++    P      T  +  S    P+         G    +
Sbjct: 4927 STTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSS------PGTATAL 4980

Query: 1741 PYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKA 1800
            P     A           P  + G TW    QT    A +S                A  
Sbjct: 4981 PALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMS---------------TATP 5025

Query: 1801 PPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKET--PTPQ 1858
                 T  T T  T   TT        G  G         +  P   P T   T  PT  
Sbjct: 5026 SSTPETVHTSTVLTATATT-------TGATG--------SVATPSSTPGTAHTTKVPTTT 5070

Query: 1859 RKGLRSS-ALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAK 1917
              G  ++ +  P    TP  T P+   + +                              
Sbjct: 5071 TTGFTATPSSSPGTALTPPTTTPMSTMSTI---------------------------HTS 5103

Query: 1918 KRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVT 1977
               E    + + T+T + T +T ST +P+  +    I   +T  T    T   GS AT++
Sbjct: 5104 STPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELT--TTATTTAATGSTATLS 5161

Query: 1978 FQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTS---QQTFTSFQPRTATVT 2034
                        TW+    S    V V         S+ GT+   +   T     TAT +
Sbjct: 5162 STPG-------TTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATAS 5214

Query: 2035 IRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRT 2080
              P++S + GTT    V+  P   P  +V       ST+  +++ T
Sbjct: 5215 TVPSSS-TVGTTRTPAVL--PSSLPTFSV-------STVSSSVLTT 5250



 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 76/337 (22%), Positives = 116/337 (34%), Gaps = 64/337 (18%)

Query: 2101 PVSTAVSAPNTVSSTPGQ-----KSLTSATSTSNIQSSASQP------PRPQQGQVKLTM 2149
            P + A S+  T SSTPG      K  T+AT+T++  S+A+        P P+      T 
Sbjct: 2579 PSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATT 2638

Query: 2150 AQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQ-------QLMQAAMP 2202
              +T        + G    +     T       P   +V P P         +L Q   P
Sbjct: 2639 PTVTSSKATPSSSPGTATALPALRSTA----TTPTATSVTPIPSSSLGTTWTRLSQTTTP 2694

Query: 2203 NGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSS 2262
              T+     +    TA T++  T T +TT A TG       +P            A ++ 
Sbjct: 2695 TATMSTATPSSTPETAHTSTVLTATATTTGA-TGSVATPSSTPGT----------AHTTK 2743

Query: 2263 VGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSK 2322
            V        TA PS+ P     P  P      T P  +  T   S +P     TH  +  
Sbjct: 2744 VPTTTTTGFTATPSSSPGTALTP--PVWISTTTTPTTRGSTVTPSSIPGT---THTAT-- 2796

Query: 2323 PQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTS 2382
                                V + + T +  +T S  +P   +Q   TT  P P+ P+T 
Sbjct: 2797 --------------------VLTTTTTTV--ATGSMATPSSSTQTSGTTHTP-PV-PNTM 2832

Query: 2383 LQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPS 2419
                 +  P S P    +  T ++   L    ++ PS
Sbjct: 2833 ATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPS 2869



 Score = 48.9 bits (115), Expect = 7e-05
 Identities = 81/343 (23%), Positives = 120/343 (34%), Gaps = 42/343 (12%)

Query: 1924 KPTVIATST--TSPTSSTTSTI--SPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQ 1979
            KPT  AT+T  T  T++ TST+  +P  KV+    +    T +K    T   SP T T  
Sbjct: 2602 KPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSK---ATPSSSPGTATAL 2658

Query: 1980 QNKNFHQTF---------------ATWVKQGQSNSGVVQVQQKVLGIIPSSTGTS----- 2019
                   T                 TW +  Q+ +    +        P +  TS     
Sbjct: 2659 PALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTA 2718

Query: 2020 QQTFTSFQPRTATVTIRPNTSGSG--GTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAI 2077
              T T      AT +  P T+ +    TT+ +     P   PG T +  P+  ST     
Sbjct: 2719 TATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPG-TALTPPVWISTTTTPT 2777

Query: 2078 IRTPVMVQPGAPQQVMTQIIRGQPVST----AVSAPNTVSSTPGQKSLTSATSTSNIQSS 2133
             R   +     P    T  +     +T    +++ P++ + T G        +T      
Sbjct: 2778 TRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHG 2837

Query: 2134 ASQPP-RPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGP 2192
             S PP  P   +   T A    L   H   +  TV       TTG  Q     ++  P P
Sbjct: 2838 RSLPPSSPHTVRTAWTSATSGILGTTH-ITEPSTVTSHTLAATTGTTQHSTPALS-SPHP 2895

Query: 2193 GQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGT 2235
              +  ++    GT      TP  TTAT+ +T T T S T   T
Sbjct: 2896 SSRTTESPPSPGTT-----TPGHTTATSRTTATATPSKTRTST 2933



 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 111/568 (19%), Positives = 186/568 (32%), Gaps = 100/568 (17%)

Query: 1918 KRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVT 1977
            + L    P  + T+ TS TS    T    +   V   + + TTGT    T  + SP   +
Sbjct: 2838 RSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSS 2897

Query: 1978 FQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRP 2037
                    +T  +    G +  G              +T TS+ T T+   +T T T+ P
Sbjct: 2898 --------RTTESPPSPGTTTPG-------------HTTATSRTTATATPSKTRTSTLLP 2936

Query: 2038 NTSGSGGTTSNSQVITGPQIR-------------PGMTVIRTPLQQSTLGKAIIRTPV-- 2082
            ++  S   T+   +   PQ               P      T       G A+   P+  
Sbjct: 2937 SSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGL 2996

Query: 2083 ----MVQPGAPQQVMTQIIRGQ----------------------------------PVST 2104
                  QPG P + + Q++                                     P + 
Sbjct: 2997 ECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTP 3056

Query: 2105 AVSAPNTVSSTPGQKSL-----TSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGH 2159
            A S+    SSTPG   +     T+AT+T +  S+A+    P    +    +    +T   
Sbjct: 3057 ATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPT 3116

Query: 2160 GGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTAT 2219
            G     T        T G     P   T    P     +A   +          L +TAT
Sbjct: 3117 GS----TATASSTQATAGT----PHVSTTATTPTVTSSKATPFSSPGTATALPALRSTAT 3168

Query: 2220 TASTTT-TTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQ 2278
            T + T+ T + +++ GT   R S+ +         T P +   +V  +     TA  +  
Sbjct: 3169 TPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTAT-PSSTPETVHTSTVLTTTATTTGA 3227

Query: 2279 PQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQ 2338
                  P S   P      +V T TT        + P  A++    ++  + P +     
Sbjct: 3228 TGSVATPSST--PGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTV 3285

Query: 2339 SPVRVQSPSQT-------RIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQP 2391
            +P  +   + T           +T S  +P   +Q   TT  P P+ P+T+     +   
Sbjct: 3286 TPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTP-PV-PNTTATTHGRSLS 3343

Query: 2392 QSQPQVQSSTQTLSSGQTLNQVTVSSPS 2419
             S P    +  T ++  TL    ++ PS
Sbjct: 3344 PSSPHTVRTAWTSATSGTLGTTHITEPS 3371



 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 85/369 (23%), Positives = 131/369 (35%), Gaps = 40/369 (10%)

Query: 1930 TSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFA 1989
            T+T + T+ST ST +P   +  AP           VLTT   +P   + +   +     A
Sbjct: 2604 TTTATTTASTGSTATPTSTLRTAP--------PPKVLTTTATTPTVTSSKATPSSSPGTA 2655

Query: 1990 TWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNS 2049
            T +   +S +        V  I  SS GT+    +     TAT++     S +  T   S
Sbjct: 2656 TALPALRS-TATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMS-TATPSSTPETAHTS 2713

Query: 2050 QVITGPQIRPGMT-VIRTPLQQSTLGKA-IIRTPVMVQPGAPQQVMTQIIRGQPVSTAVS 2107
             V+T      G T  + TP   ST G A   + P     G               +T  S
Sbjct: 2714 TVLTATATTTGATGSVATP--SSTPGTAHTTKVPTTTTTGF-------------TATPSS 2758

Query: 2108 APNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTV 2167
            +P T  + P   S T+  +T     + S  P        LT    T  T       G   
Sbjct: 2759 SPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVAT-------GSMA 2811

Query: 2168 VIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTT 2227
                  QT+G     P   T+    G+ L  ++ P+     +         TT  T  +T
Sbjct: 2812 TPSSSTQTSGTTHTPPVPNTMATTHGRSLPPSS-PHTVRTAWTSATSGILGTTHITEPST 2870

Query: 2228 VS--TTAAGTGEQRQSK---LSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQ 2282
            V+  T AA TG  + S     SP       ++ P   +++ G   A  +T   +   + +
Sbjct: 2871 VTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTR 2930

Query: 2283 TQPQSPAQP 2291
            T    P+ P
Sbjct: 2931 TSTLLPSSP 2939



 Score = 45.4 bits (106), Expect = 8e-04
 Identities = 178/872 (20%), Positives = 266/872 (30%), Gaps = 176/872 (20%)

Query: 1589 TTMTSTVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTK--LSTPSTGGSVDI 1646
            T  TS+ AT S T        K T  ++T     ST T ++T  T   L+ PST  +V +
Sbjct: 4202 TPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTV 4261

Query: 1647 ISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALP 1706
                       +T    S   T GT   S T +    T  K     FS P    + TALP
Sbjct: 4262 --------PTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT--PFSSPG---TATALP 4308

Query: 1707 SYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGIT 1766
            + R   T  +  S   +                                   P  + G T
Sbjct: 4309 ALRSTATTPTATSFTAI-----------------------------------PSSSLGTT 4333

Query: 1767 WRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRD 1826
            W    QT    A +S                  A P   T  T  + T +TTT    R  
Sbjct: 4334 WTRLSQTTTPTATMST-----------------ATPSS-TPETAHTSTVLTTTATTTR-- 4373

Query: 1827 VGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETW 1886
                          +  P   P T   T  P       +      P T + T PV I T 
Sbjct: 4374 ----------ATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTAR-TPPVWISTT 4422

Query: 1887 VAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPA 1946
                                                  P+ +  +T +PT  TT+T + A
Sbjct: 4423 TTPTTSG---------------------------STVTPSSVPGTTHTPTVLTTTTTTVA 4455

Query: 1947 QKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQN---KNFHQTFATWVKQGQSNSGVVQ 2003
               M  P S + T+GT    T  V +    T  ++    + H     W        G   
Sbjct: 4456 TGSMATPSSSTQTSGTTH--TPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTH 4513

Query: 2004 VQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTV 2063
            +             T   T TS  P   T T + +T        +S+    P   PG T 
Sbjct: 4514 I-------------TEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPP-SPGTTT 4559

Query: 2064 ----IRTPLQQSTLGKAIIRTPVMVQPGAPQQ--VMTQIIRGQPVSTAVSAPNTVSSTPG 2117
                  T    +T   +  RT  ++ P +P    + T +  G     A S     S    
Sbjct: 4560 PGHTTATSRTTATATPSKTRTSTLL-PSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMP 4618

Query: 2118 QKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQ----LTQLTQGHGGNQGLTVVIQGQG 2173
              S     + SNI+++         G      AQ    L +L Q    +    +V + + 
Sbjct: 4619 GPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNRE 4678

Query: 2174 QTTGQLQLIPQGVTVL----------PGPGQQLMQAAMPNGTVQRFLFTPLATTATTAST 2223
            Q           + V           P      M ++ P  T   ++ T L TTATT   
Sbjct: 4679 QVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTT---WILTELTTTATT--- 4732

Query: 2224 TTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTA---------- 2273
               T ST +  T         P   +    T P A +SS   + + P+TA          
Sbjct: 4733 ---TASTGSTATPSSTPGTAPPPKVLTSPATTPTA-TSSKATSSSSPRTATTLPVLTSTA 4788

Query: 2274 ----QPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQS 2329
                  S  P P +   +      QT   V T +T+  H  S  + TH  +     A  +
Sbjct: 4789 TKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTI--HPSSTPETTHTSTVLTTKATTT 4846

Query: 2330 QPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTT--TSQPIPIQPHTSLQIPS 2387
            +  S+    S     +   T +  +  +  + G  +   +T  T+  +     T+    S
Sbjct: 4847 RATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTAS 4906

Query: 2388 QGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPS 2419
             G   +      +T  L+   T   VTV + S
Sbjct: 4907 TGSTATPSSTPGTTWILTEPSTTATVTVPTGS 4938



 Score = 37.4 bits (85), Expect = 0.22
 Identities = 102/474 (21%), Positives = 165/474 (34%), Gaps = 67/474 (14%)

Query: 1967 TTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPS-STGTSQQTFTS 2025
            TT++ +  T T Q        F+T   Q  S+ G+ +        +P+ S G +   +TS
Sbjct: 2306 TTELETATTTTTQA------LFST--PQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTS 2357

Query: 2026 FQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQ 2085
                    T+   T+G   T + S   T P +       R+ L  +T G      P    
Sbjct: 2358 --------TLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTT-GSLGTWRPSQPP 2408

Query: 2086 PGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQV 2145
              AP  + T   R +P  TA +A     +T    +LTS  STS  ++S    PR      
Sbjct: 2409 TLAPTTMATS--RARPTGTASTASKEPLTTSLAPTLTSELSTSQAETST---PR-----T 2458

Query: 2146 KLTMAQLTQLTQGHG---------GNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQL 2196
            + TM+ LT  T   G           +   V     G   G ++        +   G ++
Sbjct: 2459 ETTMSPLTNTTTSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFEN----IRAAGGKM 2514

Query: 2197 MQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLP 2256
              A  P     R    P  +        T ++ T      E +  + +     +  + L 
Sbjct: 2515 CWA--PKSIECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFN-YNVRVLC 2571

Query: 2257 PAQSSSVGPAEAQPQTAQPSAQPQPQ---TQPQSPAQPEVQTQPEVQTQTTVSSHVPSEA 2313
                S      A   TA PS+ P      T+P + A     T       +T+ +  P + 
Sbjct: 2572 CDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKV 2631

Query: 2314 QPTHAQSSKPQVAAQSQPQSNVQGQSPV------RVQSPSQTRIRPSTPSQLSPGQQSQV 2367
              T A  + P V +     S+  G +           +P+ T + P   S L        
Sbjct: 2632 LTTTA--TTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLS 2689

Query: 2368 QTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVT--VSSPS 2419
            QTTT       P  ++   S   P S P+   ++  L++  T    T  V++PS
Sbjct: 2690 QTTT-------PTATM---STATPSSTPETAHTSTVLTATATTTGATGSVATPS 2733



 Score = 36.6 bits (83), Expect = 0.37
 Identities = 52/229 (22%), Positives = 81/229 (35%), Gaps = 23/229 (10%)

Query: 1483 TKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTT--TPSASCPESNSVNQVEDMEIETSE 1540
            T +   +S+ +      +L T P  K   +T TT    S+    S+S      +    S 
Sbjct: 2605 TTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRST 2664

Query: 1541 VKKVTSSPITSEEESNLSNDF--IDENGLPINKNENVNGESKRKTVITEVTTMTSTVATE 1598
                T++ +T    S+L   +  + +   P          S  +T  T  T +T+T  T 
Sbjct: 2665 ATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTS-TVLTATATTT 2723

Query: 1599 SKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVT 1658
              T             SST   A +T   TTTT    +TPS+              T +T
Sbjct: 2724 GAT-------GSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPG-----------TALT 2765

Query: 1659 TTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPS 1707
              V  S TTT  T  +++T S    T     ++  +         A PS
Sbjct: 2766 PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPS 2814



 Score = 36.2 bits (82), Expect = 0.49
 Identities = 51/233 (21%), Positives = 85/233 (36%), Gaps = 22/233 (9%)

Query: 1477 ERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEI 1536
            E +++ T +    S+    + R +  TL     + +T T   S + P S+S      +  
Sbjct: 3749 EPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATP-SSSPGTATALPA 3807

Query: 1537 ETSEVKKVTSSPITSEEESNLSNDF--IDENGLPINKNENVNGESKRKTVITEVTTMTST 1594
              S     T++ +T+   S+L   +  + +   P          S  +TV T     T+T
Sbjct: 3808 LRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTT 3867

Query: 1595 VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSK 1654
              T +   +           SST   A +T   TTTT    +TPS+              
Sbjct: 3868 TTTRATGSVATP--------SSTPGTAHTTKVPTTTTTGFTATPSSSPG----------- 3908

Query: 1655 TVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPS 1707
            T +T  V  S TTT  T  +++T S    T     ++  +         A PS
Sbjct: 3909 TALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPS 3961



 Score = 33.9 bits (76), Expect = 2.4
 Identities = 37/160 (23%), Positives = 59/160 (36%), Gaps = 15/160 (9%)

Query: 2270 PQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQS 2329
            P T   S+   P + P +      QT     T TT S+ +PS    T   +  P+V   +
Sbjct: 3555 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSS---TPGTAPPPKVLTST 3611

Query: 2330 QPQSNVQGQSPVRVQSPSQTRIRP--------STPSQLSPGQQSQVQTTTSQPIPIQPHT 2381
                           SP      P        ST +  +P     + TT +  +P Q  T
Sbjct: 3612 ATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGT--LPEQTTT 3669

Query: 2382 SLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVT--VSSPS 2419
             +   S   P S P+   ++  L++  T  + T  +S+PS
Sbjct: 3670 PMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPS 3709



 Score = 32.0 bits (71), Expect = 9.2
 Identities = 41/200 (20%), Positives = 77/200 (38%), Gaps = 13/200 (6%)

Query: 1480 SSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETS 1539
            ++ T   + SS     +   +   LP+ + + +T T T     P S+       +   T+
Sbjct: 2634 TTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTT 2693

Query: 1540 EVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVI--TEVTTMTSTVAT 1597
                ++++  +S  E+  ++  +           +V   S        T+V T T+T  T
Sbjct: 2694 PTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFT 2753

Query: 1598 ESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVV 1657
             + +            +S+T     +T TT  +TVT  S P T  +  +++      T  
Sbjct: 2754 ATPSSSPGTALTPPVWISTT-----TTPTTRGSTVTPSSIPGTTHTATVLT------TTT 2802

Query: 1658 TTTVTDSLTTTGGTLVTSMT 1677
            TT  T S+ T   +  TS T
Sbjct: 2803 TTVATGSMATPSSSTQTSGT 2822



 Score = 32.0 bits (71), Expect = 9.2
 Identities = 37/213 (17%), Positives = 79/213 (37%), Gaps = 7/213 (3%)

Query: 1479 NSSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIET 1538
            +++ T   + SS     +   +   LP+ + + +T T T   + P S+       +   T
Sbjct: 4955 STTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTT 5014

Query: 1539 SEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKR-------KTVITEVTTM 1591
            +    ++++  +S  E+  ++  +           +V   S         K   T  T  
Sbjct: 5015 TPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGF 5074

Query: 1592 TSTVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKE 1651
            T+T ++   T +        + +S+    +    T T+T +T  +T +   +        
Sbjct: 5075 TATPSSSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSST 5134

Query: 1652 QSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYST 1684
               T + T +T + TTT  T  T+   S   +T
Sbjct: 5135 LGTTRILTELTTTATTTAATGSTATLSSTPGTT 5167


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 79.3 bits (194), Expect = 5e-14
 Identities = 280/1426 (19%), Positives = 471/1426 (33%), Gaps = 202/1426 (14%)

Query: 1124 QSPNANNDQPEDLIQGCSESDSSVLRMSDPSHTTNKLYPKDRVLDDVSIRSPETKCPKQN 1183
            +SP+A          G SE  S+       +HTT   +P      D+S + P T    Q 
Sbjct: 1448 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTT--AFPDSTTTSDLS-QEPTTSHSSQG 1504

Query: 1184 SIENDIEEKVSDLASRGQEPSKSKTKGNDFFIDDSKLASADDIGTLICKNKKP------- 1236
            S E  +    +  +S GQ+ +   +   D    ++ L   D I + + +   P       
Sbjct: 1505 STEATLSPGSTTASSLGQQSTTFHSSPGD---TETTLLPDDTITSGLVEASTPTHSSTGS 1561

Query: 1237 ----LIQEESDTIVSSSKSALHSSVPKSTNDRDATPLSRAMDFEGKLGCDSESNSTLEN- 1291
                L    S +     +S    S P S++   + P + A   E      S  +ST    
Sbjct: 1562 LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTH 1621

Query: 1292 -SSDTVSIQDSSEEDMIVQNSNESISEQFRTREQ-DVEVLEPLKCELVSGESTGNCEDRL 1349
             S+ + ++  S E   +  +   + +  F TR    V V EP    + SG +     +  
Sbjct: 1622 FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGST-----ETT 1676

Query: 1350 PVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNNENRESEKKGQRTSTFQING 1409
             + G+        +       P +  +       T+   + E+  S  +   T T    G
Sbjct: 1677 ALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPG 1736

Query: 1410 KDNKPKIYLKGECLKEISESRVVSGNVEPKVNNINKIIPENDI--KSLTVKESAIRPF-I 1466
                P +    E     S        + P     + + PE+     S    E+ + P   
Sbjct: 1737 STTMPGV--SQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNT 1794

Query: 1467 NGDVIMEDFNERNSSETKSHLLSS---SDAEGNYRDSLETLPSTKESDSTQTTTPSASCP 1523
                ++E     +SS    H   S   S        + ++ PS+K++     TT SA   
Sbjct: 1795 TASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFV- 1853

Query: 1524 ESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKT 1583
            E ++ +        T+     +++   SEE + + +  +     P       +G  +  T
Sbjct: 1854 ELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEEST 1913

Query: 1584 VITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTK-LSTPSTGG 1642
                    T T+     +       + +T  SST +   S  +TT+  V +  S  S+ G
Sbjct: 1914 AYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPG 1973

Query: 1643 SVDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKV--------KLMKFS 1694
            S              TT   DS TT+G +  ++ + S + +T   V         L+  S
Sbjct: 1974 ST------------ATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGES 2021

Query: 1695 RPKKTRSG----TALPSYRKFVTKSSKKSIF-VLPNDDLKKLA----RKGGIREVPYFNY 1745
                  SG    TALP        S K + F   P      L+       G+ E    ++
Sbjct: 2022 TTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSH 2081

Query: 1746 NAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASL-----RWDDMAAKA 1800
            +   +     +P    T G++   R  T    +  S    LL AS        +   + +
Sbjct: 2082 SRPGSTHTTAFPDSTTTPGLS---RHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHS 2138

Query: 1801 PPG--------GGTTRTETSETEIT--TTEIIKRRDVGPYGIRSEYCIR---KIICPIGV 1847
             PG        G TT     +   T  ++       + P    S   +    ++    G 
Sbjct: 2139 SPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS 2198

Query: 1848 PET---PKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERV 1904
            P T   P  + +P  +G  S+A +     T     P    T   EE              
Sbjct: 2199 PRTTLSPASSTSPGLQG-ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT 2257

Query: 1905 EKEKAQAVEQQAKK-RLEQQKPTVIATSTTSPTS-------STTSTISPAQKVMVAPISG 1956
                +      ++K  +    P    T+ +S  S       STTS ISP    +      
Sbjct: 2258 HFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGS 2317

Query: 1957 SVTTGTKMVLTTKVGSPATVTFQQNKNF-------HQTFATWVKQGQSNSGVVQVQQKVL 2009
            + T G     TT   SP + T   +           ++  +  + G ++S V        
Sbjct: 2318 TTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTP 2377

Query: 2010 GIIPSST----GTSQQTFTSFQPRTATVTIR---PNTSGSGGTTSNSQVITGPQIRPGMT 2062
            G+   ST     +   T T+  PRT T ++R   P T  S   ++++ + T      G+T
Sbjct: 2378 GLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLT 2437

Query: 2063 VIRT-----------------------------------------PLQQSTLGKAIIRTP 2081
               T                                         P + +T G     TP
Sbjct: 2438 EESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTP 2497

Query: 2082 VMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQK---SLTSATSTSNIQSSASQPP 2138
              + P + +   T  + G P + ++S  +T   T  +    +L+ AT+TS+  S  S   
Sbjct: 2498 SRLSPSSTE---TTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTS 2554

Query: 2139 RPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQ 2198
              Q G    T    +  T G   +   +    G   TT    L+P   T   GP Q+   
Sbjct: 2555 HSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTT----LLPASTTT-SGPSQESTT 2609

Query: 2199 AAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPA 2258
            +    G+    L +P +TTA +    +TT  ++   T                  TL P 
Sbjct: 2610 SHSSPGSTDTAL-SPGSTTALSFGQESTTFHSSPGST----------------HTTLFPD 2652

Query: 2259 QSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHA 2318
             ++S G  EA  +    +  P+    P S   P +Q +      TT  +H  S    TH 
Sbjct: 2653 STTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGE-----STTFQTHPAS----THT 2703

Query: 2319 QSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQ-SQVQTTTSQPIPI 2377
              S P  A     +S    +SP             STP+   P    +   +  S     
Sbjct: 2704 TPSPPSTATAPVEESTTYHRSP------------GSTPTTHFPASSTTSGHSEKSTIFHS 2751

Query: 2378 QPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQL 2423
             P  S   PS     +  + +S+T  +S G T       S + P L
Sbjct: 2752 SPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGL 2797



 Score = 69.7 bits (169), Expect = 4e-11
 Identities = 126/541 (23%), Positives = 199/541 (36%), Gaps = 89/541 (16%)

Query: 1931 STTSPTSS--TTSTISPAQKV---MVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFH 1985
            STT P+SS  T + +SPA+     +V   + S  + +    TT  GSP T +  +     
Sbjct: 4024 STTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKST-- 4081

Query: 1986 QTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSF-QPRTATVTIRPNTSGSGG 2044
             TF T  +   +                +S+G S+++ TS  QP +   T  P+++ + G
Sbjct: 4082 -TFYTSPRSPDATLSPATT---------TSSGVSEESSTSHSQPGSTHTTAFPDSTTTSG 4131

Query: 2045 ------TTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIR 2098
                  T+ +SQ  T   + PG T   +  QQST   +           +P    T ++ 
Sbjct: 4132 LSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHS-----------SPGDTETTLLP 4180

Query: 2099 GQPVSTAV---SAPNTVSSTPGQKSLTSATSTS-----------NIQSSASQPPRPQQGQ 2144
               +++ +   S P   S+     +LT A+STS           +  SS+   P P    
Sbjct: 4181 DDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPS-- 4238

Query: 2145 VKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNG 2204
               T A   +++  +      T        +T  L    +  TV   PG           
Sbjct: 4239 ---TTAVPVEVSTTYHSRPSSTPTTHFSASST-TLGRSEESTTVHSSPGATGTALFPTRS 4294

Query: 2205 TVQRFLFTPLATTATTASTTTTTV--STTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSS 2262
                 +  P  +  ++ ST TT +  STT AG  E+  +  S       D TL PA ++S
Sbjct: 4295 ATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRS--PDTTLSPASTTS 4352

Query: 2263 VGPAE------AQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVS------SHVP 2310
             G +E      ++P +   +A P   T P    +          T TT+S      S + 
Sbjct: 4353 SGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLG 4412

Query: 2311 SEAQPTHAQSSKPQ------------VAAQSQPQSNVQGQSPVRVQSP--SQTRIRPSTP 2356
             E+   H+     +            +   S P  +  G SP    SP  S TR   ST 
Sbjct: 4413 PESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTG-SPHTTLSPAGSTTRQGESTT 4471

Query: 2357 SQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVS 2416
             Q  P  +    TT + P        L   S G P S P    S  + + G++    TV 
Sbjct: 4472 FQSWPNSK---DTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVH 4528

Query: 2417 S 2417
            S
Sbjct: 4529 S 4529



 Score = 67.0 bits (162), Expect = 3e-10
 Identities = 280/1451 (19%), Positives = 482/1451 (33%), Gaps = 202/1451 (13%)

Query: 1124 QSPNANNDQPEDLIQGCSESDSSVLRMSDPSHTTNKLYPKDRVLDDVSIRSPETKCPKQN 1183
            +SP+A          G SE  S+       +HTT   +P       +S + P      Q 
Sbjct: 3005 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTT--AFPDSTTTSGLS-QEPTASHSSQG 3061

Query: 1184 SIENDIEEKVSDLASRGQEPSKSKTKGNDFFIDDSKLASADDIGTLICKNKKP------- 1236
            S E  +    +  +S GQ+ +   +   D    ++ L   D I + + +   P       
Sbjct: 3062 STEATLSPGSTTASSLGQQSTTFHSSPGD---TETTLLPDDTITSGLVEASTPTHSSTGS 3118

Query: 1237 ----LIQEESDTIVSSSKSALHSSVPKSTNDRDATPLSRAMDFEGKLGCDSESNSTLEN- 1291
                L    S +     +S    S P S++   + P + A   E      S  +ST    
Sbjct: 3119 LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTH 3178

Query: 1292 -SSDTVSIQDSSEEDMIVQNSNESISEQFRTREQ-DVEVLEPLKCELVSGESTGNCEDRL 1349
             S+ + ++  S E   +  +   + +  F TR    V V EP    + SG +     +  
Sbjct: 3179 FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGST-----ETT 3233

Query: 1350 PVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNNENRESEKKGQRTSTFQING 1409
             + G+        +       P +  +       T+   + E+  S  +   T T    G
Sbjct: 3234 ALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPG 3293

Query: 1410 KDNKPKIYLKGECLKEISESRVVSGNVEPKVNNINKIIPENDIKSL---TVKESAIRPFI 1466
                P +    E     S        + P     + + PE+        + + + +    
Sbjct: 3294 STTMPGV--SQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNT 3351

Query: 1467 NGDVIMEDFNERNSSETKSHLLSS---SDAEGNYRDSLETLPSTKESDSTQTTTPSASCP 1523
                ++E     +SS    H   S   S        + ++ P++K++     TT SA   
Sbjct: 3352 TASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAF-- 3409

Query: 1524 ESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKT 1583
                      +E+ T+     +S+P T    S+ +    +E+         V+       
Sbjct: 3410 ----------VELSTTSHGSPSSTPTTHFSASSTTLGRSEES-------TTVHSSPVATA 3452

Query: 1584 VITEVTTMTSTVATESKTVIKVEKGDKQTVV-----SSTENCAKSTVTTTTTTVTKLSTP 1638
                    T++   E  T      G  QT+      +++    +ST + ++TT T  S P
Sbjct: 3453 TTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAP 3512

Query: 1639 STGGSV--DIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKV-------- 1688
            ST  ++  +  S      +  TT   DS TT+G +  ++ + S + +T   V        
Sbjct: 3513 STTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTS 3572

Query: 1689 KLMKFSRPKKTRSG----TALPSYRKFVTKSSKKSIF-VLPNDDLKKLA----RKGGIRE 1739
             L+  S      SG    TALP        S K + F   P      L+       G+ E
Sbjct: 3573 VLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSE 3632

Query: 1740 VPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAK 1799
                +++   +     +P    T G++   R  T    +  S    LL AS      + +
Sbjct: 3633 ESTTSHSRPGSTHTTAFPDSTTTPGLS---RHSTTSHSSPGSTDTTLLPASTTTSGSSQE 3689

Query: 1800 APPGGGTT-RTETSETEITTTEIIKRRD--------------VGPYGIRSEYCIR---KI 1841
            +     ++  T+T+ +  +TT +   ++              + P    S   +    ++
Sbjct: 3690 STTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRV 3749

Query: 1842 ICPIGVPET---PKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIR 1898
                G P T   P  + +P  +G  S+A +     T     P    T   EE        
Sbjct: 3750 HSSTGSPRTTLSPASSTSPGLQG-ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSP 3808

Query: 1899 AFAERVEKEKAQAVEQQAKK-RLEQQKPTVIATSTTSPTS-------STTSTISPAQKVM 1950
                      +      ++K  +    P    T+ +S  S       STTS ISP    +
Sbjct: 3809 GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI 3868

Query: 1951 VAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNF-------HQTFATWVKQGQSNSGVVQ 2003
                  + T G     TT   SP + T   +           ++  +  + G ++S V  
Sbjct: 3869 TTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSP 3928

Query: 2004 VQQKVLGIIPSST----GTSQQTFTSFQPRTATVTIR---PNTSGSGGTTSNSQVITGPQ 2056
                  G+   ST     +   T T+  PR+ T ++R   P T  S   ++++ + T   
Sbjct: 3929 ASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDS 3988

Query: 2057 IRPGMTVIRT-----------------------------------------PLQQSTLGK 2075
               G+T   T                                         P + +T G 
Sbjct: 3989 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 4048

Query: 2076 AIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQK---SLTSATSTSNIQS 2132
                TP  + P + +   T  + G P + ++S  +T   T  +    +L+ AT+TS+  S
Sbjct: 4049 VGESTPSRLSPSSTE---TTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVS 4105

Query: 2133 SASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGP 2192
              S     Q G    T       T   G +Q  T     QG T   L     G T     
Sbjct: 4106 EESSTSHSQPGSTHTT--AFPDSTTTSGLSQEPTTSHSSQGSTEATLS---PGSTTASSL 4160

Query: 2193 GQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQD 2252
            GQQ        G  +  L      T+     +T T S+T +               +H  
Sbjct: 4161 GQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGS---------------LH-- 4203

Query: 2253 KTLPPAQSSSVG-PAEAQPQTAQPSAQPQPQTQPQSPAQP-EVQTQPEVQTQTTVSSHVP 2310
             TL PA S+S G   E+    + PS+     + P + A P EV T    +  +T ++H  
Sbjct: 4204 TTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHF- 4262

Query: 2311 SEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTT 2370
              A  T    S+      S P +      P R  S +   +   T S +S G        
Sbjct: 4263 -SASSTTLGRSEESTTVHSSPGATGTALFPTR--SATSVLVGEPTTSPISSGSTETTALP 4319

Query: 2371 TSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQP 2430
             S         S    S   P+S     S   T SSG  +++ + +S SRP        P
Sbjct: 4320 GSTTTAGLSEKSTTFYS--SPRSPDTTLSPASTTSSG--VSEESTTSHSRPGSMHTTAFP 4375

Query: 2431 QVIAVPQLQQQ 2441
                +P + Q+
Sbjct: 4376 SSTTMPGVSQE 4386



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 123/545 (22%), Positives = 183/545 (33%), Gaps = 97/545 (17%)

Query: 1931 STTSPTSS--TTSTISPAQKV---MVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFH 1985
            STT P+SS  T + +SPA+     +V   + S  + +    TT  GSP T +  +     
Sbjct: 1384 STTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTF 1443

Query: 1986 QTF----------ATWVKQG---QSNSGVVQVQQKVLGIIPSSTGTS---QQTFTSFQPR 2029
             T           AT    G   +S++   Q         P ST TS   Q+  TS   +
Sbjct: 1444 YTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQ 1503

Query: 2030 TAT-VTIRPNTS-----GSGGTTSNSQ-------VITGPQIRPGMTVIRTPLQQSTLGKA 2076
             +T  T+ P ++     G   TT +S        ++    I  G+    TP   ST    
Sbjct: 1504 GSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLH 1563

Query: 2077 IIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQ 2136
               TP        Q+  T         T  S P++  +TP     T+A     ++ S + 
Sbjct: 1564 TTLTPASSTSAGLQEEST---------TFQSWPSSSDTTPSPPGTTAAP----VEVSTTY 1610

Query: 2137 PPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGP---- 2192
              RP         A  T L    G ++  T V    G T   L       +VL G     
Sbjct: 1611 HSRPSSTPTTHFSASSTTL----GRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTS 1666

Query: 2193 ---GQQLMQAAMPNGTVQRFLF---TPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQ 2246
                      A+P  T    L    T   ++  +  TT +  STT++G  E+  +  S  
Sbjct: 1667 PISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRP 1726

Query: 2247 MQVH--------------QDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPE 2292
               H              Q+ T   +   S     +   T   S  P+  T   SP   E
Sbjct: 1727 GSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTE 1786

Query: 2293 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIR 2352
                P+     T +S +   + P H+ +  P         +  QG+S      PS     
Sbjct: 1787 TTLLPD----NTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTM 1842

Query: 2353 PSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQ 2412
            P+ P            TTTS          L   S G P S P    S  + + G++   
Sbjct: 1843 PAPP------------TTTS------AFVELSTTSHGSPSSTPTTHFSASSTTLGRSEES 1884

Query: 2413 VTVSS 2417
             TV S
Sbjct: 1885 TTVHS 1889



 Score = 65.5 bits (158), Expect = 8e-10
 Identities = 119/546 (21%), Positives = 186/546 (34%), Gaps = 76/546 (13%)

Query: 1913 EQQAKKRLEQQKPTVIATSTTSPTS----STTSTISPAQKVMVAPISGSVTTGTKMVLT- 1967
            E  A   +     T ++  TT+P+S    STT   SP           + T+G     T 
Sbjct: 335  ESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTP 394

Query: 1968 --TKVGSPATVTFQQNKNFHQ----TFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQ 2021
              +  GSP T     +   H+    TF +W     ++              PS T ++  
Sbjct: 395  VHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPA------------PSGTTSAFV 442

Query: 2022 TFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQS-TLGKAIIRT 2080
              ++    + + T   + S S  T  +S+  T     P  T    P  +S T G     T
Sbjct: 443  KLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEEST 502

Query: 2081 PVMVQPGAPQQVM---TQIIRGQPVSTAV---SAPNTVSSTPGQKSLTSATSTSNIQSSA 2134
                 PG+ Q +    +    G    +A    S  +T SSTP   S T+A + ++  SS 
Sbjct: 503  AYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTP---STTAALAHTSYHSSL 559

Query: 2135 SQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQ 2194
                            +  +    H     +   +   G T     ++    T  P    
Sbjct: 560  GSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPS---VLVGDSTPSPISSG 616

Query: 2195 QLMQAAMPNGTVQRFLF---TPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQ 2251
             +   A+P  T +  L    T   ++  +  TT    S T++G  E+  +  S     H 
Sbjct: 617  SMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHT 676

Query: 2252 -----DKTLP------PAQSSSVGPAE---AQPQTAQPSAQPQPQTQPQSPAQPEVQTQP 2297
                   T+P       A  SS GP +   +   T   S  P+  T    P   E    P
Sbjct: 677  TAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLP 736

Query: 2298 EVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPS 2357
            +     T +S +   + P H+ +  P         +  QG+S      PS    RP+ P 
Sbjct: 737  D----NTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPP- 791

Query: 2358 QLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTV-S 2416
                       TTTS    ++P T+    S G P S P    S ++ +SG      T  S
Sbjct: 792  -----------TTTS--AFVEPSTT----SHGSPSSIPTTHISARSTTSGLVEESTTYHS 834

Query: 2417 SPSRPQ 2422
            SP   Q
Sbjct: 835  SPGSTQ 840



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 125/575 (21%), Positives = 201/575 (34%), Gaps = 101/575 (17%)

Query: 1925 PTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNF 1984
            P+   ++T+    STTS ISP    +      + T G     TT   SP + T   +   
Sbjct: 2760 PSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPAS 2819

Query: 1985 -------HQTFATWVKQGQSNSGVVQVQQKVLGIIPSST----GTSQQTFTSFQPRTATV 2033
                    ++  +  + G ++S V        G+   ST     +   T T+  PR+ T 
Sbjct: 2820 MTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTT 2879

Query: 2034 TIR---PNTSGSGGTTSNSQVITGPQIRPGMTVIRT------------------------ 2066
            ++R   P T  S   ++++ + T      G+T   T                        
Sbjct: 2880 SVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGE 2939

Query: 2067 -----------------PLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAP 2109
                             P + +T G     TP  + P + +   T  + G P + ++S  
Sbjct: 2940 ESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTE---TTTLPGSPTTPSLSEK 2996

Query: 2110 NTVSSTPGQK---SLTSATSTSNIQSSASQPPRPQQGQV-------KLTMAQLTQLTQGH 2159
            +T   T  +    +L+ AT+TS+  S  S     Q G           T + L+Q     
Sbjct: 2997 STTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTAS 3056

Query: 2160 GGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLF---TPLAT 2216
              +QG T      G TT    L  Q  T    PG       +P+ T+   L    TP  +
Sbjct: 3057 HSSQGSTEATLSPGSTTAS-SLGQQSTTFHSSPG-DTETTLLPDDTITSGLVEASTPTHS 3114

Query: 2217 TATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAE-AQPQTAQP 2275
            +  +  TT T  S+T+AG  E+     + Q       T P    ++  P E +    ++P
Sbjct: 3115 STGSLHTTLTPASSTSAGLQEE---STTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRP 3171

Query: 2276 SAQP------QPQTQPQSPAQPEVQTQP--------EVQTQTTVSSHVPSEAQPTHAQSS 2321
            S+ P         T  +S     V + P          ++ T+V    P+   P  + S+
Sbjct: 3172 SSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPT-TSPISSGST 3230

Query: 2322 KPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHT 2381
            +      S   + +  +S     SP       S  S  S G     ++TTS   P   HT
Sbjct: 3231 ETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSE--ESTTSHSRPGSTHT 3288

Query: 2382 -----SLQIP--SQGQPQSQPQVQSSTQTLSSGQT 2409
                 S  +P  SQ    S     S+  TLS G T
Sbjct: 3289 TAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGST 3323



 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 124/525 (23%), Positives = 188/525 (35%), Gaps = 77/525 (14%)

Query: 1925 PTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNF 1984
            P  ++T+  S  SST +T   A          S T G     TT   SP          F
Sbjct: 4243 PVEVSTTYHSRPSSTPTTHFSAS---------STTLGRSEESTTVHSSPGATG---TALF 4290

Query: 1985 HQTFATWVKQGQSNSGVVQVQQKVLGIIPSST---GTSQQTFTSFQ-PRTATVTIRPNTS 2040
                AT V  G+  +  +         +P ST   G S+++ T +  PR+   T+ P ++
Sbjct: 4291 PTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPAST 4350

Query: 2041 GSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQ 2100
             S G +  S   T    RPG ++  T    ST             PG  Q+         
Sbjct: 4351 TSSGVSEES---TTSHSRPG-SMHTTAFPSST-----------TMPGVSQESTASHSSPG 4395

Query: 2101 PVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHG 2160
               T +S  +T +S+ G +S T  +S  + +++         G ++ +       T  H 
Sbjct: 4396 STDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEAS-------TPVHS 4448

Query: 2161 GNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTA-- 2218
                    +   G TT Q     +  T    P  +    A P  T     F  L+TT+  
Sbjct: 4449 STGSPHTTLSPAGSTTRQ----GESTTFQSWPNSKDTTPAPPTTTSA---FVELSTTSHG 4501

Query: 2219 TTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAE------AQPQT 2272
            + +ST TT  S ++   G   +S       V    T  PA+S++ G  E      + P +
Sbjct: 4502 SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGS 4561

Query: 2273 AQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEA-----QPTHAQSSKPQVAA 2327
             Q    P+  T   +  + E  T     T  T+SS  PS       +PT   SS    A 
Sbjct: 4562 TQTMHFPESNT---TSGRGEESTTSHSSTTHTISS-APSTTSALVEEPTSYHSSPGSTAT 4617

Query: 2328 QSQPQSN-VQGQSPVRVQSPSQ-----TRIRP--STPSQL------SPGQQSQVQTTTSQ 2373
               P S+   G+S     S S      T + P  ST S L      SP     ++TT   
Sbjct: 4618 THFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALP 4677

Query: 2374 PIPIQPHTSLQIPS-QGQPQSQPQVQSSTQTLSSGQTLNQVTVSS 2417
                 P  S +  +    P S P    S  + + G++    TV S
Sbjct: 4678 GSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHS 4722



 Score = 58.9 bits (141), Expect = 7e-08
 Identities = 110/515 (21%), Positives = 177/515 (34%), Gaps = 42/515 (8%)

Query: 1931 STTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVG--SPATVTFQQNKNFHQTF 1988
            +T SP S+T S++ P      +   GS  T      TT  G    +T       + H T 
Sbjct: 4399 TTLSPGSTTASSLGPESTTFHSS-PGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTL 4457

Query: 1989 A---TWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGT 2045
            +   +  +QG+S +       K     P +T ++    ++    + + T   + S S  T
Sbjct: 4458 SPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTT 4517

Query: 2046 TSNSQVITGPQIRPGMTVIR-TPLQQSTLGKAIIRTPVMVQPGAPQQVM-----TQIIRG 2099
               S+  T     P  T    +P + +T G     T     PG+ Q +      T   RG
Sbjct: 4518 LGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRG 4577

Query: 2100 QPVSTAVSAP-NTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQG 2158
            +  +T+ S+  +T+SS P   S      TS   SS              T  +  + T  
Sbjct: 4578 EESTTSHSSTTHTISSAPSTTSALVEEPTS-YHSSPGSTATTHFPDSSTTSGRSEESTAS 4636

Query: 2159 HGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTA 2218
            H        ++     TT  L       T  P     +   A+P  T    L     T  
Sbjct: 4637 HSSQDATGTIVLPARSTTSVLL---GESTTSPISSGSMETTALPGSTTTPGLSEKSTTFH 4693

Query: 2219 TTASTTTTT-VSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSA 2277
            ++ S+T TT  S ++   G   +S       V    T  PA+S++ G  E          
Sbjct: 4694 SSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPG 4753

Query: 2278 QPQ----PQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEA---QPTHAQSSKPQVAAQSQ 2330
              Q    P++   S    E +T     T T  S    + A   +PT   SS   +A    
Sbjct: 4754 STQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHF 4813

Query: 2331 PQS-----------------NVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQ 2373
            P+S                 +  G +P+     +  RI  ST   +SPG       +T+ 
Sbjct: 4814 PESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTAT 4873

Query: 2374 PIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQ 2408
               +   +++   S   P       S T +  SG+
Sbjct: 4874 TPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGE 4908



 Score = 57.8 bits (138), Expect = 2e-07
 Identities = 124/551 (22%), Positives = 195/551 (35%), Gaps = 76/551 (13%)

Query: 1930 TSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKN------ 1983
            TS ++P+SS   T      V V  I+GS  T   +  +T  G     T   +        
Sbjct: 178  TSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEESTVSHSGPGATGTT 237

Query: 1984 -FHQTFATWVKQGQSNSGVVQVQQKVLGIIPSST---GTSQQTFTSFQ-PRTATVTIRPN 2038
             F    AT V  G+  +  +         +P ST   G S+++ T +  PR+   T+ P 
Sbjct: 238  LFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPA 297

Query: 2039 TSGSGGTTSNSQVITGPQIRPGMT-VIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQII 2097
             + S G +  S   T    RPG T  I  P   +  G +   T     PG+    ++   
Sbjct: 298  RTTSSGVSEKS---TTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLS--- 351

Query: 2098 RGQPVSTAVSA----PNTVSSTPGQKSLTSA---TSTSNIQSSASQPPRPQQGQVKLTMA 2150
               P +T  S+      T  S+PG    T     T+TS +   AS P     G    T++
Sbjct: 352  ---PGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLE-ASTPVHSSTGSPHTTLS 407

Query: 2151 QLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFL 2210
              +  T               +G+ T   Q  P      P P          +GT   F+
Sbjct: 408  PSSSTTH--------------EGEPT-TFQSWPSSKDTSPAP----------SGTTSAFV 442

Query: 2211 FTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAE--- 2267
                   ++ +ST TT  S ++   G   +S       V    T PPA+S++ G  E   
Sbjct: 443  KLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEEST 502

Query: 2268 ---AQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQ 2324
                 P + Q    P+  T      +          T+++  S   + A  ++  S    
Sbjct: 503  AYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGST 562

Query: 2325 VAAQSQPQSNVQGQSPVRVQSPSQ-----TRIRP--STPSQL------SPGQQSQVQTTT 2371
                 +  S + G+S     S S      T + P  STPS L      SP     ++TT 
Sbjct: 563  ETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTA 622

Query: 2372 SQPIPIQPHTSLQIPS-QGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQP 2430
                  +P  S +  +    P+S           SSG  +++ + +S SRP        P
Sbjct: 623  LPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSG--VSEESTTSHSRPGSTHTTAFP 680

Query: 2431 QVIAVPQLQQQ 2441
                +P L Q+
Sbjct: 681  GSTTMPGLSQE 691



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 120/579 (20%), Positives = 201/579 (34%), Gaps = 108/579 (18%)

Query: 1926 TVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFH 1985
            T    STT P  S  ST S +      P   +++ G+    T     P   TF       
Sbjct: 677  TAFPGSTTMPGLSQESTASHSSP---GPTDTTLSPGST---TASSLGPEYTTFHSRPGST 730

Query: 1986 QTFATWVKQGQSNSGVVQVQQKVLG--------IIPSSTGTSQQTFTSFQ---------- 2027
            +T  T +    + SG+++    V          + P+ + T Q   T+F           
Sbjct: 731  ET--TLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRP 788

Query: 2028 --PRTATVTIRPNTSGSGGTTS------NSQVITGPQIR--------PGMT-VIRTPLQQ 2070
              P T +  + P+T+  G  +S      +++  T   +         PG T  +  P   
Sbjct: 789  APPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESD 848

Query: 2071 STLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTA--VSAPNTVSSTPGQKSLT-----S 2123
            +T G+    T             T  I   P +T+  V  P +  S+PG  + T     S
Sbjct: 849  TTSGRGEEST-------TSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSS 901

Query: 2124 ATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIP 2183
             TS  + +S+AS   +   G + L     T +  G      ++    G  +TT     +P
Sbjct: 902  TTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPIS---SGSMETTA----LP 954

Query: 2184 QGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTAS---------------TTTTTV 2228
             G T  PG    L + +    +  R   T L+  +TT+S               T TT  
Sbjct: 955  -GSTTTPG----LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAF 1009

Query: 2229 STTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSP 2288
              +    G  R S  S       D TL PA +++ GP++    +   S        P S 
Sbjct: 1010 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGST 1069

Query: 2289 AQPEV------------QTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQ--VAAQSQPQSN 2334
                              T   +   +T SS +   +   H+ +  P+  ++  S     
Sbjct: 1070 TALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPG 1129

Query: 2335 VQGQSPVRVQSPSQTRIRPSTPS-QLSPGQQSQV--QTTTSQPIPIQP-------HTSLQ 2384
            +QG+S      P+ T   PS PS   +P ++S    ++  S P    P       H+   
Sbjct: 1130 LQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKS 1189

Query: 2385 IPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQL 2423
                  P +     SS  + +SG+  +  +  SP   ++
Sbjct: 1190 TIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI 1228



 Score = 57.0 bits (136), Expect = 3e-07
 Identities = 127/575 (22%), Positives = 195/575 (33%), Gaps = 101/575 (17%)

Query: 1925 PTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTT---------------- 1968
            P+   ++T+    STTS ISP    +      + T G     TT                
Sbjct: 1203 PSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPAS 1262

Query: 1969 ----KVGSPATVTFQQNKNFHQTF--ATWVKQGQSNSGVVQVQQK----VLGIIPSSTGT 2018
                 VG  +T +  Q  + H T   A+    G S                 + P ST T
Sbjct: 1263 MTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTT 1322

Query: 2019 S----QQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITG--PQIRPGMTVIRT------ 2066
            S    + T    +P +   T+    S + G T  S    G     + G+    T      
Sbjct: 1323 SVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGE 1382

Query: 2067 -----------------PLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAP 2109
                             P + +T G     TP  + P + +   T  + G P + ++S  
Sbjct: 1383 ESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTE---TTTLPGSPTTPSLSEK 1439

Query: 2110 NTVSSTPGQK---SLTSATSTSNIQSSASQPPRPQQGQV-------KLTMAQLTQLTQGH 2159
            +T   T  +    +L+ AT+TS+  S  S     Q G           T + L+Q     
Sbjct: 1440 STTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTS 1499

Query: 2160 GGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLF---TPLAT 2216
              +QG T      G TT    L  Q  T    PG       +P+ T+   L    TP  +
Sbjct: 1500 HSSQGSTEATLSPGSTTAS-SLGQQSTTFHSSPG-DTETTLLPDDTITSGLVEASTPTHS 1557

Query: 2217 TATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAE-AQPQTAQP 2275
            +  +  TT T  S+T+AG  E+     + Q       T P    ++  P E +    ++P
Sbjct: 1558 STGSLHTTLTPASSTSAGLQEE---STTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRP 1614

Query: 2276 SAQP------QPQTQPQSPAQPEVQTQP--------EVQTQTTVSSHVPSEAQPTHAQSS 2321
            S+ P         T  +S     V + P          ++ T+V    P+   P  + S+
Sbjct: 1615 SSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPT-TSPISSGST 1673

Query: 2322 KPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHT 2381
            +      S   + +  +S     SP       S  S  S G     ++TTS   P   HT
Sbjct: 1674 ETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSE--ESTTSHSRPGSTHT 1731

Query: 2382 -----SLQIP--SQGQPQSQPQVQSSTQTLSSGQT 2409
                 S  +P  SQ    S     S+  TLS G T
Sbjct: 1732 TAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGST 1766



 Score = 42.0 bits (97), Expect = 0.009
 Identities = 108/474 (22%), Positives = 173/474 (36%), Gaps = 61/474 (12%)

Query: 1929 ATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVT----FQQNKNF 1984
            +T+  S  SST +T   A    +     S T  +  V T    SPA  T     +++  +
Sbjct: 4689 STTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAY 4748

Query: 1985 H----QTFATWVKQGQSNSGVVQVQQ-------KVLGIIPSSTGTSQQTFTSF--QPRTA 2031
            H     T      +  + SG  +  +         +   PS+T    +  TS+   P + 
Sbjct: 4749 HSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSI 4808

Query: 2032 TVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQ 2091
              T  P +S + G +  S          G+T +  P   +T G+    T   + PG+   
Sbjct: 4809 ATTHFPESSTTSGRSEESTASHSSPDTNGITPL--PAHFTTSGRIAESTTFYISPGS--- 4863

Query: 2092 VMTQIIRGQPVSTAVSAPNTV---SSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLT 2148
             M   +     +  +SA +T+   SS    ++L+ A+ TS   SS S  P     Q + T
Sbjct: 4864 -METTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTS---SSISGEPTSLYSQAEST 4919

Query: 2149 -MAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQ 2207
                    T   G +Q  T      G T  +  L P  +T      +     + P   + 
Sbjct: 4920 HTTAFPASTTTSGLSQESTTFHSKPGST--ETTLSPGSITTSSFAQEFTTPHSQPGSALS 4977

Query: 2208 RFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLP----PAQSSSV 2263
                +P +TT    S  +TT   ++ G+ E      S  M +H  ++ P    P  + +V
Sbjct: 4978 --TVSPASTTVPGLSEESTTF-YSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTV 5034

Query: 2264 GPAE------AQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTH 2317
             PA        Q  TA  S+     T P     P   T  ++  + T     PS   PT+
Sbjct: 5035 LPATLTTTDIGQESTAFHSSSDATGTTP----LPARSTASDLVGEPTTFYISPS---PTY 5087

Query: 2318 AQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPS--QLSPG--QQSQV 2367
                   +   S   S +  +S     SPS T    ST S   L+PG  Q+ Q+
Sbjct: 5088 T-----TLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAPGLCQEGQI 5136



 Score = 38.1 bits (87), Expect = 0.13
 Identities = 56/243 (23%), Positives = 92/243 (37%), Gaps = 24/243 (9%)

Query: 1478 RNSSETKSHLLSSSDAEGNYRDSLETLPSTKES--DSTQTTTPSASCPESNSVNQVEDME 1535
            R+ + T S    +S   G    +  + P +  S      TTTP  S  ES +V       
Sbjct: 2809 RSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLS-EESTTVYSSSPGS 2867

Query: 1536 IETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVI--TEVTTMTS 1593
             ET+   + T++ +  EE +   +     +     ++   +G ++  T    +  +T T 
Sbjct: 2868 TETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTG 2927

Query: 1594 TVAT-------ESKTVIKVEKGDKQTVVSSTENCAKSTV---TTTTTTVTKLSTPSTGGS 1643
              AT       E  T      G   T +S   +     V   T +  + +   T +  GS
Sbjct: 2928 LPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS 2987

Query: 1644 VDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGT 1703
                S+ E+S T  T+  +   T +  T  TS  VS+E ST         S+P  T + T
Sbjct: 2988 PTTPSLSEKSTTFYTSPRSPDATLSPAT-TTSSGVSEESST-------SHSQPGSTHT-T 3038

Query: 1704 ALP 1706
            A P
Sbjct: 3039 AFP 3041



 Score = 37.4 bits (85), Expect = 0.22
 Identities = 44/195 (22%), Positives = 73/195 (37%), Gaps = 9/195 (4%)

Query: 1475 FNERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDM 1534
            ++    S    H   S    G   +S  +  ST  + S+  +T SA   E  S +     
Sbjct: 832  YHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGS 891

Query: 1535 EIETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVITEVTTMTST 1594
               T      T+S     EES  S+   D  G  +     +   S    ++ E TT  S 
Sbjct: 892  TATTHFPDSSTTSG--RSEESTASHSSQDATGTIV-----LPARSTTSVLLGESTT--SP 942

Query: 1595 VATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSK 1654
            +++ S     +        +S       S+  +  TT++  ST S+G S +  + + +  
Sbjct: 943  ISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPG 1002

Query: 1655 TVVTTTVTDSLTTTG 1669
            +  TT   DS TT G
Sbjct: 1003 STHTTAFPDSTTTPG 1017



 Score = 35.4 bits (80), Expect = 0.83
 Identities = 56/243 (23%), Positives = 91/243 (37%), Gaps = 24/243 (9%)

Query: 1478 RNSSETKSHLLSSSDAEGNYRDSLETLPSTKES--DSTQTTTPSASCPESNSVNQVEDME 1535
            R+ + T S    +S   G    +  + P +  S      TTTP  S  ES +V       
Sbjct: 1252 RSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLS-EESTTVYSSSRGS 1310

Query: 1536 IETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVI--TEVTTMTS 1593
             ET+     T++ +  EE +   +     +     ++   +G ++  T    +  +T T 
Sbjct: 1311 TETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTG 1370

Query: 1594 TVAT-------ESKTVIKVEKGDKQTVVSSTENCAKSTV---TTTTTTVTKLSTPSTGGS 1643
              AT       E  T      G   T +S   +     V   T +  + +   T +  GS
Sbjct: 1371 LPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS 1430

Query: 1644 VDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGT 1703
                S+ E+S T  T+  +   T +  T  TS  VS+E ST         S+P  T + T
Sbjct: 1431 PTTPSLSEKSTTFYTSPRSPDATLSPAT-TTSSGVSEESST-------SHSQPGSTHT-T 1481

Query: 1704 ALP 1706
            A P
Sbjct: 1482 AFP 1484


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 79.0 bits (193), Expect = 7e-14
 Identities = 205/988 (20%), Positives = 348/988 (35%), Gaps = 120/988 (12%)

Query: 1794 DDMAAKAPPGGGTTRTETS---------ETEITTTEIIKRRDVGPYGIRSEYCIRKIICP 1844
            + +AA A  GGG +   +          E +++     +RR +     R++   +     
Sbjct: 14   EGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKG---- 69

Query: 1845 IGVPETPKETPTPQRKGLRSSALRPK---------RPETPKQTGPVIIETWVAEEELELW 1895
              VP    E+P+  RK    S+  PK         RP  P  +     +T+ +E++L   
Sbjct: 70   -SVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGR 128

Query: 1896 EIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPIS 1955
                 + +  K +    E+     +      V A S  S   S  +  +P   +  +  S
Sbjct: 129  SPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVS---SVVNKFNPFDLISDSEAS 185

Query: 1956 GSVTTGTKMVLTTKVGSPATVTF-----QQNKNFHQTFATW---VKQGQSNSGVVQVQQK 2007
               TT  + V+  + G P  +       Q  K   +        ++Q  +   +   Q +
Sbjct: 186  QEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPE 245

Query: 2008 VLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGM-TVIRT 2066
             +   P  TG   Q  T   P+T    +      S   T  + ++ G  ++P + +  + 
Sbjct: 246  KIKSQPPGTGKPIQGPTQ-TPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKP 304

Query: 2067 PLQQSTLGKAIIRTP--VMVQPG-----APQQVMTQIIRGQP--VSTAVSAPNTVSSTPG 2117
            P+QQ T GK   + P     QPG     A    +T+ +  QP  V   V  P T    P 
Sbjct: 305  PIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK--PP 362

Query: 2118 QKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTG 2177
             + L  A   +  Q+ + +P   Q G   L                       G G+T  
Sbjct: 363  AQPLGPAKPPAQ-QTGSEKPSSEQPGPKALAQPP-------------------GVGKTPA 402

Query: 2178 QLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTP-LATTATTASTTTTTVSTTAAGTG 2236
            Q           PGP +   Q     GT +     P L + A     T T V     G  
Sbjct: 403  QQ----------PGPAKPPTQQV---GTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449

Query: 2237 EQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQ 2296
              +Q+            T PP+Q    GPA+  PQ   P A+P PQ QP S   P  Q  
Sbjct: 450  PAQQAGPGKTSAQQTGPTKPPSQLP--GPAKPPPQQPGP-AKPPPQ-QPGSAKPPSQQP- 504

Query: 2297 PEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTP 2356
                      S  P   QP  A+ S PQ    ++P S   G +    Q PS        P
Sbjct: 505  ---------GSTKPPPQQPGPAKPS-PQQPGSTKPPSQQPGSAKPSAQQPS--------P 546

Query: 2357 SQLSPGQQSQVQTTTSQPIPIQPHT----SLQIPSQGQPQSQPQVQSSTQTL---SSGQT 2409
            ++ S  Q ++  + T    P+QP T    + Q PSQG P++   + ++T+ L        
Sbjct: 547  AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN 606

Query: 2410 LNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKL 2469
             N  T    +   L    P P +  V    ++   L+    + +    A     PQ    
Sbjct: 607  FNTCTECQTTVCSLCGFNPNPHLTEV----KEWLCLNCQMKRALGGDLAPVPSSPQPKLK 662

Query: 2470 QLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQA 2529
              P+    + +  + Q Q     + A+ ++ L +  + +      KQ  +        + 
Sbjct: 663  TAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQ 722

Query: 2530 SNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQA 2589
              +++ + K    K  +V    +Q K+    ++ +  +M+     +        K +  +
Sbjct: 723  PPEADSLSKPAPPKEPSVPS--EQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780

Query: 2590 AKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDL 2649
            +K + + E       K ++ K S       E++     K       D +I        + 
Sbjct: 781  SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES 840

Query: 2650 KIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPP-PAVQHTGLLSTPTLPAAS 2708
            K +K+ D +Q  +    A     ++P P A P P  SP PP P       + TP      
Sbjct: 841  KGQKQVDPVQKKEEPKKAQ--TKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKP 898

Query: 2709 QKRKREEEKDSSSKSKKKKMISTTSKET 2736
            Q++ R    +  S +   K   TT +ET
Sbjct: 899  QEQSRRFSLNLGSITDAPKSQPTTPQET 926



 Score = 53.1 bits (126), Expect = 4e-06
 Identities = 171/788 (21%), Positives = 266/788 (33%), Gaps = 134/788 (17%)

Query: 2037 PNTSGSGGTTSNSQVITGPQIRPGMTV--IRTPLQQSTLGKAIIRTPVMVQPGAPQQVMT 2094
            P      G TS  Q  TGP   P       + P QQ    K   + P   +P + Q   T
Sbjct: 450  PAQQAGPGKTSAQQ--TGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST 507

Query: 2095 QIIRGQPVSTAVSAPNTVSST--PGQK---SLTSATSTSNIQSSASQPPRP--QQGQVKL 2147
            +    QP   A  +P    ST  P Q+   +  SA   S  + SA Q  +P  Q G  K 
Sbjct: 508  KPPPQQP-GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKP 566

Query: 2148 TMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGV----------TVL------PG 2191
                    +     +QGL   I     TT  L  +P+            TV       P 
Sbjct: 567  LQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPN 626

Query: 2192 PG-QQLMQAAMPNGTVQRFLFTPLATTATTASTT--TTTVSTTAAGTGEQRQSKLSPQ-M 2247
            P   ++ +    N  ++R L   LA   ++      T  V+TT+A       SK SPQ  
Sbjct: 627  PHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA------VSKSSPQPQ 680

Query: 2248 QVHQDKTLPPAQSSSVGPAEAQPQT--------AQPSA---QPQPQTQPQSPAQPEVQTQ 2296
            Q    K   P Q  S  P   +P            PSA   QP        PA P+  + 
Sbjct: 681  QTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSV 740

Query: 2297 PEVQTQTTVSSHVPSEAQ----PTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIR 2352
            P  Q +  V+   P + +     T   SS         P S VQ Q+  +   P +T   
Sbjct: 741  PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTD-- 798

Query: 2353 PSTPSQLSPGQQSQVQTTTSQPIP-------IQPHTSLQIPSQGQPQSQP-----QVQSS 2400
             + PSQ  P    +V    S+ IP       I  H      S+GQ Q  P     + + +
Sbjct: 799  SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKA 858

Query: 2401 TQTLSSGQTLNQVTVSSPSRPQLQIQQPQP---QVIAVPQLQQQVQVLSQIQSQVVAQIQ 2457
               +S       +   SP+ P      P+P   Q +  PQ   + Q  S+  S  +  I 
Sbjct: 859  QTKMSPKPDAKPMPKGSPTPPG-----PRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSIT 913

Query: 2458 AQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQ-------------------AASVQ 2498
                  P   +  +  ++    A    Q  N+++                     A S  
Sbjct: 914  DAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP 973

Query: 2499 EQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEH----LKQK 2554
               Q   +   Q      + I +K+E    A+ + E   +Q         E     +K  
Sbjct: 974  PTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDS 1033

Query: 2555 KSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSAL 2614
            KS+T     E Q+ ++  ++                K  K E +    +++ N       
Sbjct: 1034 KSLTA----EPQKAVLPTKL---------------EKSPKPESTCPLCKTELNIGSKDPP 1074

Query: 2615 LFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVT 2674
             F    + + ++             E+QE L  + + ++           A++     + 
Sbjct: 1075 NFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQR-----------AISGQLGDIR 1123

Query: 2675 PAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSK 2734
              PPAP  P  SP P P    +   + P  P     +K+E+E     K++ +K+I    K
Sbjct: 1124 KMPPAPSGPKASPMPVPTESSSQKTAVP--PQVKLVKKQEQE----VKTEAEKVILEKVK 1177

Query: 2735 ETKKDTKL 2742
            ET    K+
Sbjct: 1178 ETLSMEKI 1185



 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 152/726 (20%), Positives = 276/726 (38%), Gaps = 133/726 (18%)

Query: 2112 VSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQG 2171
            V S+P  K  T+  +T++  S +S  P+PQQ   K   A    L++     +   +V Q 
Sbjct: 653  VPSSPQPKLKTAPVTTTSAVSKSS--PQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQP 710

Query: 2172 --QGQTTGQLQLIPQGVTVL-PGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTV 2228
               G  + + +  P+  ++  P P ++    ++P+   +  +             TT  V
Sbjct: 711  TLHGSPSAKAKQPPEADSLSKPAPPKE---PSVPSEQDKAPVADDKPKQPKMVKPTTDLV 767

Query: 2229 STTAAGTGEQ-RQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQ------------- 2274
            S+++A T      SK+  Q +   +KT PP ++ S  P+++ P T +             
Sbjct: 768  SSSSATTKPDIPSSKVQSQAE---EKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRP 824

Query: 2275 -----------PSAQPQPQTQ------------PQSPAQPEVQTQPEVQTQTTVSSHVPS 2311
                       PS++ + Q Q             Q+   P+   +P  +   T     P+
Sbjct: 825  ASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPT 884

Query: 2312 EAQ--PTHAQSSKPQV--------------AAQSQ---PQSNVQGQ-SPVRVQSPSQTRI 2351
              Q  PT  QS KPQ               A +SQ   PQ  V G+         SQ   
Sbjct: 885  AGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASN 944

Query: 2352 RPSTPSQLSPGQQSQVQTTTSQ-PIPIQPHTSLQIP-SQGQ----PQSQPQVQSSTQTLS 2405
              ST  Q  P  QS       Q P P QP TS   P S GQ    P     V+  T+   
Sbjct: 945  LISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKA-P 1003

Query: 2406 SGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQ 2465
            + + L      +P+  + + ++  P +     L  + Q       + V   + ++S  P+
Sbjct: 1004 AAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQ-------KAVLPTKLEKSPKPE 1056

Query: 2466 Q----IKLQLPIQIQQSSAVQT-----HQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQ 2516
                  K +L I  +      T     +Q+ N+          ++Q    L  Q Q+   
Sbjct: 1057 STCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS 1116

Query: 2517 QQI-EIKREHTLQASNQSE--IIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQ 2573
             Q+ +I++     +  ++    +  +   +  AV   +K  K      + E +++I+   
Sbjct: 1117 GQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKV 1176

Query: 2574 VMKYILDKI------DKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEIL 2627
                 ++KI      D++++++  ++ +  ++++K+      K    L   +E++R+E  
Sbjct: 1177 KETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKK----LIPEEEKIRSE-- 1230

Query: 2628 KKRALL--------DKDLQIEVQ----EELKRDL-----KIKKEKDLMQLAQATAVAAPC 2670
            +K+ LL        DK L  E +    EE K DL     +I +EK   ++A  T V    
Sbjct: 1231 EKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKT-VQEGK 1289

Query: 2671 PPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAAS---------QKRKREEEKDSSS 2721
             P T     P   P S P         +   P  P  +         +K ++E++K  +S
Sbjct: 1290 QPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTS 1349

Query: 2722 KSKKKK 2727
             S++ K
Sbjct: 1350 SSQQPK 1355



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 20/40 (50%), Positives = 22/40 (55%), Gaps = 7/40 (17%)

Query: 2666 VAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLP 2705
            ++A  PP  P PP PP PPP PPPPP       L  PT P
Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPP-------LPPPTSP 2433



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 43/154 (27%), Positives = 61/154 (39%), Gaps = 19/154 (12%)

Query: 2239 RQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQ-PSAQPQPQTQPQSPAQP-----E 2292
            R +++  Q  + + +T P  + S   P + Q ++   P   P  Q Q  SPA P      
Sbjct: 3843 RPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTS 3902

Query: 2293 VQTQPEVQTQTTVSSHV-PSEAQPTH----AQSSKPQVAAQSQPQSNVQGQSPVRV--QS 2345
               Q   + QT     V P + QPT       S  PQV     PQ + Q  S + V  Q 
Sbjct: 3903 YTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQQK 3962

Query: 2346 PSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQP 2379
            P QT +       L P   S  +   +QP+ I P
Sbjct: 3963 PRQTTL------YLEPKITSNYEVIRNQPLMIAP 3990



 Score = 42.4 bits (98), Expect = 0.007
 Identities = 19/40 (47%), Positives = 20/40 (50%)

Query: 2669 PCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAAS 2708
            P PP  P PP PP PPP P PPP      +L    L  AS
Sbjct: 2408 PPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVAS 2447



 Score = 37.4 bits (85), Expect = 0.22
 Identities = 67/300 (22%), Positives = 104/300 (34%), Gaps = 50/300 (16%)

Query: 2225 TTTVSTTAAGTGEQRQSKL----SPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQ 2280
            +TT  T+    G+++ +      SP +     K  P  +SSS+  +   P    P   P 
Sbjct: 2357 STTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP 2416

Query: 2281 PQTQPQSPAQPEVQTQPE----VQTQTTVSSHVPSEAQPTHAQSSKPQVA---AQSQPQS 2333
            P   P  P      T P+     + + TV+S V +      A ++    A   +   P +
Sbjct: 2417 PPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVT 2476

Query: 2334 NVQGQSPVRV-QSPSQT--------RIRPSTPSQLSPGQQSQVQTTTSQPIPIQP----- 2379
             +   +P  V   PS          R  PS P         Q+ TTT +P  I P     
Sbjct: 2477 RICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGL 2536

Query: 2380 ------------HTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQ 2427
                            ++PS   P S P    S+   S   T   V ++ PS P      
Sbjct: 2537 SLTSSMTLNLVTSADYKLPSPTSPLS-PHSNKSSPRFSKSLTETYVVITLPSEPGTPTDS 2595

Query: 2428 PQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQ----SSAVQT 2483
               Q I    L           S+ +  ++   S VP    +++PI  +Q    S A+QT
Sbjct: 2596 SASQAITSWPLGS--------PSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQT 2647



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 138/716 (19%), Positives = 245/716 (34%), Gaps = 130/716 (18%)

Query: 2079 RTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPP 2138
            + P MV+P       T ++     +T    P++   +  ++  T    T + + S S PP
Sbjct: 755  KQPKMVKP------TTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPP 808

Query: 2139 R-----PQQGQVKLTMAQLTQLTQGHG------GNQGLTVVIQGQGQTTGQLQL------ 2181
                  P   +     A  +++    G      G + +  V + +     Q ++      
Sbjct: 809  TGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868

Query: 2182 --IPQGVTVLPGP----GQQL---MQAAMPNGTVQRFLFTPLATTATTASTTTT---TVS 2229
              +P+G    PGP    GQ +    Q+  P    +RF     + T    S  TT   TV+
Sbjct: 869  KPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVT 928

Query: 2230 TTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPA 2289
                G G    S+ S  +         P   S  GP     Q   PS  P  Q  P+S  
Sbjct: 929  GKLFGFGASIFSQASNLISTAGQ----PGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTG 984

Query: 2290 QPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQT 2349
            Q               +   P+++ P   ++  P  A + +P++    Q+P   ++ ++ 
Sbjct: 985  Q---------------APPAPAKSIPVKKETKAP-AAEKLEPKAE---QAPTVKRTETEK 1025

Query: 2350 RIRPSTPSQ-LSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQ 2408
            +  P   S+ L+   Q  V  T  +  P    T     ++    S+     +T T    +
Sbjct: 1026 KPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCT----E 1081

Query: 2409 TLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQ-VLSQIQSQ-------------VVA 2454
              NQV       P   + + Q  +    Q Q+ +   L  I+               V  
Sbjct: 1082 CKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPT 1141

Query: 2455 QIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKK 2514
            +  +Q++ VP Q+KL      +Q   V+T      V ++       ++++  +    QK+
Sbjct: 1142 ESSSQKTAVPPQVKLVK----KQEQEVKTE--AEKVILEKVKETLSMEKIPPMVTTDQKQ 1195

Query: 2515 KQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQV 2574
            ++ ++E  +   LQ                    + L ++K + P E +      + ++ 
Sbjct: 1196 EESKLEKDKASALQEK------------------KPLPEEKKLIPEEEK------IRSEE 1231

Query: 2575 MKYILD--KIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRAL 2632
             K +L+  K   E+K+   + K     EQK            L K + Q+  E L+ R +
Sbjct: 1232 KKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD----------LLKSQVQIAEEKLEGR-V 1280

Query: 2633 LDKDLQIEVQEELKRD-------LKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPP 2685
              K +Q   Q + K +         + KE D       T    P PP T  P        
Sbjct: 1281 APKTVQEGKQPQTKMEGLPSGTPQSLPKEDD---KTTKTIKEQPQPPCTAKPDQVEPGKE 1337

Query: 2686 SPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTK 2741
                      T     P  P          +  SSS  +   +I T  K+  K  K
Sbjct: 1338 KTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLK 1393



 Score = 36.6 bits (83), Expect = 0.37
 Identities = 38/152 (25%), Positives = 59/152 (38%), Gaps = 12/152 (7%)

Query: 2258 AQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTT--VSSHVPSEAQP 2315
            ++ SS  P   + Q      +  PQT+      P+ QT+ ++   T+        S A P
Sbjct: 3837 SEVSSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALP 3896

Query: 2316 THAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQP- 2374
            T A +S  Q +   Q     Q  SP + Q   Q     S   Q+ P       T T QP 
Sbjct: 3897 TQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQP-------TPTPQPS 3949

Query: 2375 --IPIQPHTSLQIPSQGQPQSQPQVQSSTQTL 2404
              +P Q     Q P Q     +P++ S+ + +
Sbjct: 3950 YQLPSQMMVIQQKPRQTTLYLEPKITSNYEVI 3981



 Score = 35.0 bits (79), Expect = 1.1
 Identities = 22/115 (19%), Positives = 66/115 (57%), Gaps = 12/115 (10%)

Query: 2557 MTPAEREENQRMIVCNQVMKY-------ILDKIDKEEKQAAKKRKREESVEQKRSKQNAT 2609
            + P E ++ Q++ +  ++++          ++++ E ++  + R++E+ + QK+ ++  +
Sbjct: 3203 IVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQKKLEELQS 3262

Query: 2610 KLSALLFKHKEQLRAE-ILKKRALLDKDLQIE----VQEELKRDLKIKKEKDLMQ 2659
                LLF+ +E+ +A+ ++++  L  + LQ+E    +Q++L + L+ +K + + Q
Sbjct: 3263 MKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQIYQ 3317



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 36/154 (23%), Positives = 55/154 (35%), Gaps = 14/154 (9%)

Query: 2671 PPVTPAP--PAPPAPPPSPPP---PPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKK 2725
            PP  P P  P+P  P  + PP   P + + +    +P  P+A Q  K    +  S K  +
Sbjct: 510  PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTK-PVSQTGSGKPLQ 568

Query: 2726 KKMISTTSKETKKD--TKLYC-ICKTP-----YDESKFYIGCDRCQNWYHGRCVGILQSE 2777
               +S ++K+       K  C +C T        E   +  C  CQ      C       
Sbjct: 569  PPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPH 628

Query: 2778 AELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLK 2811
               + E++C  CQ        L P+       LK
Sbjct: 629  LTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLK 662



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 16/29 (55%), Positives = 16/29 (55%), Gaps = 1/29 (3%)

Query: 2661 AQATAVAAPCPPVTPAPPAPPAPPPSPPP 2689
            AQ      P PP  P PP PP PPP PPP
Sbjct: 2403 AQPPPPPPPPPPPPPPPPPPP-PPPLPPP 2430



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 5/87 (5%)

Query: 8    PPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSS- 66
            PP  P  P      P PPPPP PP + P   +  + + +       A       T L + 
Sbjct: 2406 PPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETT 2465

Query: 67   ----PRGGSSSRRKPPPPPPAPPSTSA 89
                  G   +R     PPP PP  S+
Sbjct: 2466 AVLRSNGLPVTRICTTAPPPVPPKPSS 2492



 Score = 34.3 bits (77), Expect = 1.9
 Identities = 34/168 (20%), Positives = 71/168 (42%), Gaps = 26/168 (15%)

Query: 503  LIDCLDKDYWEAELCKILEEMREEIHRHMDITEDLTNKARGSNKSFLAAANEEILESIRA 562
            L + L+    E E+ +  EE ++   +  D  +D+ +      KS       E ++ I  
Sbjct: 1455 LSETLEITISEEEIKESQEERKDTFKK--DSQQDIPSSKDHKEKS-------EFVDDITT 1505

Query: 563  KKGDIDNVKSPEETEKD-----KNETENDSKDAEKNREEFEDQSLEKDS----------- 606
            ++   D+V+   E+E       K  T   S  +++ ++E    S E++            
Sbjct: 1506 RREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSA 1565

Query: 607  -DDKTPDDDPEQGKSEVGDFKSEKSNGELSESPGAGKGASGSTRIITR 653
             +D +  +D E  ++++ +  S   + +  E+ G GK  +G  R +TR
Sbjct: 1566 DEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTR 1613



 Score = 33.1 bits (74), Expect = 4.1
 Identities = 30/116 (25%), Positives = 40/116 (34%), Gaps = 28/116 (24%)

Query: 7   RPPKQ---PAAPAAERCAPAPPPP-----------------PPPPTSGPI-------GGL 39
           +PP Q   PA P  ++  PA PPP                 PPP   GP        G  
Sbjct: 468 KPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGST 527

Query: 40  RSRHRGSSRGRWAAAQAEVA-PKTRLSSPRGGSSSRRKPPPPPPAPPSTSAPGRGG 94
           +   +     + +A Q   A P  + S+     +   KP  PP   PS   P   G
Sbjct: 528 KPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQG 583



 Score = 32.7 bits (73), Expect = 5.4
 Identities = 22/91 (24%), Positives = 35/91 (38%), Gaps = 9/91 (9%)

Query: 7   RPPKQPAA---PAAERCAPAPPPPPPP----PTSGPIGGLRSRHRGSSRGRWAAAQAEVA 59
           +PP QP+    P A++     PP  PP    P + P+G   ++      G    +  +  
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLG--PAKPPAQQTGSEKPSSEQPG 387

Query: 60  PKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP 90
           PK     P  G +  ++P P  P       P
Sbjct: 388 PKALAQPPGVGKTPAQQPGPAKPPTQQVGTP 418



 Score = 32.0 bits (71), Expect = 9.2
 Identities = 13/25 (52%), Positives = 13/25 (52%)

Query: 11   QPAAPAAERCAPAPPPPPPPPTSGP 35
            QP  P      P PPPPPPPP   P
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLP 2428


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 79.0 bits (193), Expect = 7e-14
 Identities = 205/988 (20%), Positives = 348/988 (35%), Gaps = 120/988 (12%)

Query: 1794 DDMAAKAPPGGGTTRTETS---------ETEITTTEIIKRRDVGPYGIRSEYCIRKIICP 1844
            + +AA A  GGG +   +          E +++     +RR +     R++   +     
Sbjct: 14   EGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKG---- 69

Query: 1845 IGVPETPKETPTPQRKGLRSSALRPK---------RPETPKQTGPVIIETWVAEEELELW 1895
              VP    E+P+  RK    S+  PK         RP  P  +     +T+ +E++L   
Sbjct: 70   -SVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGR 128

Query: 1896 EIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPIS 1955
                 + +  K +    E+     +      V A S  S   S  +  +P   +  +  S
Sbjct: 129  SPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVS---SVVNKFNPFDLISDSEAS 185

Query: 1956 GSVTTGTKMVLTTKVGSPATVTF-----QQNKNFHQTFATW---VKQGQSNSGVVQVQQK 2007
               TT  + V+  + G P  +       Q  K   +        ++Q  +   +   Q +
Sbjct: 186  QEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPE 245

Query: 2008 VLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGM-TVIRT 2066
             +   P  TG   Q  T   P+T    +      S   T  + ++ G  ++P + +  + 
Sbjct: 246  KIKSQPPGTGKPIQGPTQ-TPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKP 304

Query: 2067 PLQQSTLGKAIIRTP--VMVQPG-----APQQVMTQIIRGQP--VSTAVSAPNTVSSTPG 2117
            P+QQ T GK   + P     QPG     A    +T+ +  QP  V   V  P T    P 
Sbjct: 305  PIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK--PP 362

Query: 2118 QKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTG 2177
             + L  A   +  Q+ + +P   Q G   L                       G G+T  
Sbjct: 363  AQPLGPAKPPAQ-QTGSEKPSSEQPGPKALAQPP-------------------GVGKTPA 402

Query: 2178 QLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTP-LATTATTASTTTTTVSTTAAGTG 2236
            Q           PGP +   Q     GT +     P L + A     T T V     G  
Sbjct: 403  QQ----------PGPAKPPTQQV---GTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449

Query: 2237 EQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQ 2296
              +Q+            T PP+Q    GPA+  PQ   P A+P PQ QP S   P  Q  
Sbjct: 450  PAQQAGPGKTSAQQTGPTKPPSQLP--GPAKPPPQQPGP-AKPPPQ-QPGSAKPPSQQP- 504

Query: 2297 PEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTP 2356
                      S  P   QP  A+ S PQ    ++P S   G +    Q PS        P
Sbjct: 505  ---------GSTKPPPQQPGPAKPS-PQQPGSTKPPSQQPGSAKPSAQQPS--------P 546

Query: 2357 SQLSPGQQSQVQTTTSQPIPIQPHT----SLQIPSQGQPQSQPQVQSSTQTL---SSGQT 2409
            ++ S  Q ++  + T    P+QP T    + Q PSQG P++   + ++T+ L        
Sbjct: 547  AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN 606

Query: 2410 LNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKL 2469
             N  T    +   L    P P +  V    ++   L+    + +    A     PQ    
Sbjct: 607  FNTCTECQTTVCSLCGFNPNPHLTEV----KEWLCLNCQMKRALGGDLAPVPSSPQPKLK 662

Query: 2470 QLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQA 2529
              P+    + +  + Q Q     + A+ ++ L +  + +      KQ  +        + 
Sbjct: 663  TAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQ 722

Query: 2530 SNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQA 2589
              +++ + K    K  +V    +Q K+    ++ +  +M+     +        K +  +
Sbjct: 723  PPEADSLSKPAPPKEPSVPS--EQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780

Query: 2590 AKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDL 2649
            +K + + E       K ++ K S       E++     K       D +I        + 
Sbjct: 781  SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES 840

Query: 2650 KIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPP-PAVQHTGLLSTPTLPAAS 2708
            K +K+ D +Q  +    A     ++P P A P P  SP PP P       + TP      
Sbjct: 841  KGQKQVDPVQKKEEPKKAQ--TKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKP 898

Query: 2709 QKRKREEEKDSSSKSKKKKMISTTSKET 2736
            Q++ R    +  S +   K   TT +ET
Sbjct: 899  QEQSRRFSLNLGSITDAPKSQPTTPQET 926



 Score = 53.1 bits (126), Expect = 4e-06
 Identities = 171/788 (21%), Positives = 266/788 (33%), Gaps = 134/788 (17%)

Query: 2037 PNTSGSGGTTSNSQVITGPQIRPGMTV--IRTPLQQSTLGKAIIRTPVMVQPGAPQQVMT 2094
            P      G TS  Q  TGP   P       + P QQ    K   + P   +P + Q   T
Sbjct: 450  PAQQAGPGKTSAQQ--TGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST 507

Query: 2095 QIIRGQPVSTAVSAPNTVSST--PGQK---SLTSATSTSNIQSSASQPPRP--QQGQVKL 2147
            +    QP   A  +P    ST  P Q+   +  SA   S  + SA Q  +P  Q G  K 
Sbjct: 508  KPPPQQP-GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKP 566

Query: 2148 TMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGV----------TVL------PG 2191
                    +     +QGL   I     TT  L  +P+            TV       P 
Sbjct: 567  LQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPN 626

Query: 2192 PG-QQLMQAAMPNGTVQRFLFTPLATTATTASTT--TTTVSTTAAGTGEQRQSKLSPQ-M 2247
            P   ++ +    N  ++R L   LA   ++      T  V+TT+A       SK SPQ  
Sbjct: 627  PHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA------VSKSSPQPQ 680

Query: 2248 QVHQDKTLPPAQSSSVGPAEAQPQT--------AQPSA---QPQPQTQPQSPAQPEVQTQ 2296
            Q    K   P Q  S  P   +P            PSA   QP        PA P+  + 
Sbjct: 681  QTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSV 740

Query: 2297 PEVQTQTTVSSHVPSEAQ----PTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIR 2352
            P  Q +  V+   P + +     T   SS         P S VQ Q+  +   P +T   
Sbjct: 741  PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTD-- 798

Query: 2353 PSTPSQLSPGQQSQVQTTTSQPIP-------IQPHTSLQIPSQGQPQSQP-----QVQSS 2400
             + PSQ  P    +V    S+ IP       I  H      S+GQ Q  P     + + +
Sbjct: 799  SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKA 858

Query: 2401 TQTLSSGQTLNQVTVSSPSRPQLQIQQPQP---QVIAVPQLQQQVQVLSQIQSQVVAQIQ 2457
               +S       +   SP+ P      P+P   Q +  PQ   + Q  S+  S  +  I 
Sbjct: 859  QTKMSPKPDAKPMPKGSPTPPG-----PRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSIT 913

Query: 2458 AQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQ-------------------AASVQ 2498
                  P   +  +  ++    A    Q  N+++                     A S  
Sbjct: 914  DAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP 973

Query: 2499 EQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEH----LKQK 2554
               Q   +   Q      + I +K+E    A+ + E   +Q         E     +K  
Sbjct: 974  PTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDS 1033

Query: 2555 KSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSAL 2614
            KS+T     E Q+ ++  ++                K  K E +    +++ N       
Sbjct: 1034 KSLTA----EPQKAVLPTKL---------------EKSPKPESTCPLCKTELNIGSKDPP 1074

Query: 2615 LFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVT 2674
             F    + + ++             E+QE L  + + ++           A++     + 
Sbjct: 1075 NFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQR-----------AISGQLGDIR 1123

Query: 2675 PAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSK 2734
              PPAP  P  SP P P    +   + P  P     +K+E+E     K++ +K+I    K
Sbjct: 1124 KMPPAPSGPKASPMPVPTESSSQKTAVP--PQVKLVKKQEQE----VKTEAEKVILEKVK 1177

Query: 2735 ETKKDTKL 2742
            ET    K+
Sbjct: 1178 ETLSMEKI 1185



 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 152/726 (20%), Positives = 276/726 (38%), Gaps = 133/726 (18%)

Query: 2112 VSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQG 2171
            V S+P  K  T+  +T++  S +S  P+PQQ   K   A    L++     +   +V Q 
Sbjct: 653  VPSSPQPKLKTAPVTTTSAVSKSS--PQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQP 710

Query: 2172 --QGQTTGQLQLIPQGVTVL-PGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTV 2228
               G  + + +  P+  ++  P P ++    ++P+   +  +             TT  V
Sbjct: 711  TLHGSPSAKAKQPPEADSLSKPAPPKE---PSVPSEQDKAPVADDKPKQPKMVKPTTDLV 767

Query: 2229 STTAAGTGEQ-RQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQ------------- 2274
            S+++A T      SK+  Q +   +KT PP ++ S  P+++ P T +             
Sbjct: 768  SSSSATTKPDIPSSKVQSQAE---EKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRP 824

Query: 2275 -----------PSAQPQPQTQ------------PQSPAQPEVQTQPEVQTQTTVSSHVPS 2311
                       PS++ + Q Q             Q+   P+   +P  +   T     P+
Sbjct: 825  ASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPT 884

Query: 2312 EAQ--PTHAQSSKPQV--------------AAQSQ---PQSNVQGQ-SPVRVQSPSQTRI 2351
              Q  PT  QS KPQ               A +SQ   PQ  V G+         SQ   
Sbjct: 885  AGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASN 944

Query: 2352 RPSTPSQLSPGQQSQVQTTTSQ-PIPIQPHTSLQIP-SQGQ----PQSQPQVQSSTQTLS 2405
              ST  Q  P  QS       Q P P QP TS   P S GQ    P     V+  T+   
Sbjct: 945  LISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKA-P 1003

Query: 2406 SGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQ 2465
            + + L      +P+  + + ++  P +     L  + Q       + V   + ++S  P+
Sbjct: 1004 AAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQ-------KAVLPTKLEKSPKPE 1056

Query: 2466 Q----IKLQLPIQIQQSSAVQT-----HQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQ 2516
                  K +L I  +      T     +Q+ N+          ++Q    L  Q Q+   
Sbjct: 1057 STCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS 1116

Query: 2517 QQI-EIKREHTLQASNQSE--IIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQ 2573
             Q+ +I++     +  ++    +  +   +  AV   +K  K      + E +++I+   
Sbjct: 1117 GQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKV 1176

Query: 2574 VMKYILDKI------DKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEIL 2627
                 ++KI      D++++++  ++ +  ++++K+      K    L   +E++R+E  
Sbjct: 1177 KETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKK----LIPEEEKIRSE-- 1230

Query: 2628 KKRALL--------DKDLQIEVQ----EELKRDL-----KIKKEKDLMQLAQATAVAAPC 2670
            +K+ LL        DK L  E +    EE K DL     +I +EK   ++A  T V    
Sbjct: 1231 EKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKT-VQEGK 1289

Query: 2671 PPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAAS---------QKRKREEEKDSSS 2721
             P T     P   P S P         +   P  P  +         +K ++E++K  +S
Sbjct: 1290 QPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTS 1349

Query: 2722 KSKKKK 2727
             S++ K
Sbjct: 1350 SSQQPK 1355



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 20/40 (50%), Positives = 22/40 (55%), Gaps = 7/40 (17%)

Query: 2666 VAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLP 2705
            ++A  PP  P PP PP PPP PPPPP       L  PT P
Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPP-------LPPPTSP 2433



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 43/154 (27%), Positives = 61/154 (39%), Gaps = 19/154 (12%)

Query: 2239 RQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQ-PSAQPQPQTQPQSPAQP-----E 2292
            R +++  Q  + + +T P  + S   P + Q ++   P   P  Q Q  SPA P      
Sbjct: 3843 RPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTS 3902

Query: 2293 VQTQPEVQTQTTVSSHV-PSEAQPTH----AQSSKPQVAAQSQPQSNVQGQSPVRV--QS 2345
               Q   + QT     V P + QPT       S  PQV     PQ + Q  S + V  Q 
Sbjct: 3903 YTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQQK 3962

Query: 2346 PSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQP 2379
            P QT +       L P   S  +   +QP+ I P
Sbjct: 3963 PRQTTL------YLEPKITSNYEVIRNQPLMIAP 3990



 Score = 42.4 bits (98), Expect = 0.007
 Identities = 19/40 (47%), Positives = 20/40 (50%)

Query: 2669 PCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAAS 2708
            P PP  P PP PP PPP P PPP      +L    L  AS
Sbjct: 2408 PPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVAS 2447



 Score = 37.4 bits (85), Expect = 0.22
 Identities = 67/300 (22%), Positives = 104/300 (34%), Gaps = 50/300 (16%)

Query: 2225 TTTVSTTAAGTGEQRQSKL----SPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQ 2280
            +TT  T+    G+++ +      SP +     K  P  +SSS+  +   P    P   P 
Sbjct: 2357 STTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP 2416

Query: 2281 PQTQPQSPAQPEVQTQPE----VQTQTTVSSHVPSEAQPTHAQSSKPQVA---AQSQPQS 2333
            P   P  P      T P+     + + TV+S V +      A ++    A   +   P +
Sbjct: 2417 PPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVT 2476

Query: 2334 NVQGQSPVRV-QSPSQT--------RIRPSTPSQLSPGQQSQVQTTTSQPIPIQP----- 2379
             +   +P  V   PS          R  PS P         Q+ TTT +P  I P     
Sbjct: 2477 RICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGL 2536

Query: 2380 ------------HTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQ 2427
                            ++PS   P S P    S+   S   T   V ++ PS P      
Sbjct: 2537 SLTSSMTLNLVTSADYKLPSPTSPLS-PHSNKSSPRFSKSLTETYVVITLPSEPGTPTDS 2595

Query: 2428 PQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQ----SSAVQT 2483
               Q I    L           S+ +  ++   S VP    +++PI  +Q    S A+QT
Sbjct: 2596 SASQAITSWPLGS--------PSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQT 2647



 Score = 37.0 bits (84), Expect = 0.29
 Identities = 138/716 (19%), Positives = 245/716 (34%), Gaps = 130/716 (18%)

Query: 2079 RTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPP 2138
            + P MV+P       T ++     +T    P++   +  ++  T    T + + S S PP
Sbjct: 755  KQPKMVKP------TTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPP 808

Query: 2139 R-----PQQGQVKLTMAQLTQLTQGHG------GNQGLTVVIQGQGQTTGQLQL------ 2181
                  P   +     A  +++    G      G + +  V + +     Q ++      
Sbjct: 809  TGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868

Query: 2182 --IPQGVTVLPGP----GQQL---MQAAMPNGTVQRFLFTPLATTATTASTTTT---TVS 2229
              +P+G    PGP    GQ +    Q+  P    +RF     + T    S  TT   TV+
Sbjct: 869  KPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVT 928

Query: 2230 TTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPA 2289
                G G    S+ S  +         P   S  GP     Q   PS  P  Q  P+S  
Sbjct: 929  GKLFGFGASIFSQASNLISTAGQ----PGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTG 984

Query: 2290 QPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQT 2349
            Q               +   P+++ P   ++  P  A + +P++    Q+P   ++ ++ 
Sbjct: 985  Q---------------APPAPAKSIPVKKETKAP-AAEKLEPKAE---QAPTVKRTETEK 1025

Query: 2350 RIRPSTPSQ-LSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQ 2408
            +  P   S+ L+   Q  V  T  +  P    T     ++    S+     +T T    +
Sbjct: 1026 KPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCT----E 1081

Query: 2409 TLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQ-VLSQIQSQ-------------VVA 2454
              NQV       P   + + Q  +    Q Q+ +   L  I+               V  
Sbjct: 1082 CKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPT 1141

Query: 2455 QIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKK 2514
            +  +Q++ VP Q+KL      +Q   V+T      V ++       ++++  +    QK+
Sbjct: 1142 ESSSQKTAVPPQVKLVK----KQEQEVKTE--AEKVILEKVKETLSMEKIPPMVTTDQKQ 1195

Query: 2515 KQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQV 2574
            ++ ++E  +   LQ                    + L ++K + P E +      + ++ 
Sbjct: 1196 EESKLEKDKASALQEK------------------KPLPEEKKLIPEEEK------IRSEE 1231

Query: 2575 MKYILD--KIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRAL 2632
             K +L+  K   E+K+   + K     EQK            L K + Q+  E L+ R +
Sbjct: 1232 KKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD----------LLKSQVQIAEEKLEGR-V 1280

Query: 2633 LDKDLQIEVQEELKRD-------LKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPP 2685
              K +Q   Q + K +         + KE D       T    P PP T  P        
Sbjct: 1281 APKTVQEGKQPQTKMEGLPSGTPQSLPKEDD---KTTKTIKEQPQPPCTAKPDQVEPGKE 1337

Query: 2686 SPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTK 2741
                      T     P  P          +  SSS  +   +I T  K+  K  K
Sbjct: 1338 KTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLK 1393



 Score = 36.6 bits (83), Expect = 0.37
 Identities = 38/152 (25%), Positives = 59/152 (38%), Gaps = 12/152 (7%)

Query: 2258 AQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTT--VSSHVPSEAQP 2315
            ++ SS  P   + Q      +  PQT+      P+ QT+ ++   T+        S A P
Sbjct: 3837 SEVSSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALP 3896

Query: 2316 THAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQP- 2374
            T A +S  Q +   Q     Q  SP + Q   Q     S   Q+ P       T T QP 
Sbjct: 3897 TQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQP-------TPTPQPS 3949

Query: 2375 --IPIQPHTSLQIPSQGQPQSQPQVQSSTQTL 2404
              +P Q     Q P Q     +P++ S+ + +
Sbjct: 3950 YQLPSQMMVIQQKPRQTTLYLEPKITSNYEVI 3981



 Score = 35.0 bits (79), Expect = 1.1
 Identities = 22/115 (19%), Positives = 66/115 (57%), Gaps = 12/115 (10%)

Query: 2557 MTPAEREENQRMIVCNQVMKY-------ILDKIDKEEKQAAKKRKREESVEQKRSKQNAT 2609
            + P E ++ Q++ +  ++++          ++++ E ++  + R++E+ + QK+ ++  +
Sbjct: 3203 IVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQKKLEELQS 3262

Query: 2610 KLSALLFKHKEQLRAE-ILKKRALLDKDLQIE----VQEELKRDLKIKKEKDLMQ 2659
                LLF+ +E+ +A+ ++++  L  + LQ+E    +Q++L + L+ +K + + Q
Sbjct: 3263 MKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQIYQ 3317



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 36/154 (23%), Positives = 55/154 (35%), Gaps = 14/154 (9%)

Query: 2671 PPVTPAP--PAPPAPPPSPPP---PPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKK 2725
            PP  P P  P+P  P  + PP   P + + +    +P  P+A Q  K    +  S K  +
Sbjct: 510  PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTK-PVSQTGSGKPLQ 568

Query: 2726 KKMISTTSKETKKD--TKLYC-ICKTP-----YDESKFYIGCDRCQNWYHGRCVGILQSE 2777
               +S ++K+       K  C +C T        E   +  C  CQ      C       
Sbjct: 569  PPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPH 628

Query: 2778 AELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLK 2811
               + E++C  CQ        L P+       LK
Sbjct: 629  LTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLK 662



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 16/29 (55%), Positives = 16/29 (55%), Gaps = 1/29 (3%)

Query: 2661 AQATAVAAPCPPVTPAPPAPPAPPPSPPP 2689
            AQ      P PP  P PP PP PPP PPP
Sbjct: 2403 AQPPPPPPPPPPPPPPPPPPP-PPPLPPP 2430



 Score = 34.7 bits (78), Expect = 1.4
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 5/87 (5%)

Query: 8    PPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSS- 66
            PP  P  P      P PPPPP PP + P   +  + + +       A       T L + 
Sbjct: 2406 PPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETT 2465

Query: 67   ----PRGGSSSRRKPPPPPPAPPSTSA 89
                  G   +R     PPP PP  S+
Sbjct: 2466 AVLRSNGLPVTRICTTAPPPVPPKPSS 2492



 Score = 34.3 bits (77), Expect = 1.9
 Identities = 34/168 (20%), Positives = 71/168 (42%), Gaps = 26/168 (15%)

Query: 503  LIDCLDKDYWEAELCKILEEMREEIHRHMDITEDLTNKARGSNKSFLAAANEEILESIRA 562
            L + L+    E E+ +  EE ++   +  D  +D+ +      KS       E ++ I  
Sbjct: 1455 LSETLEITISEEEIKESQEERKDTFKK--DSQQDIPSSKDHKEKS-------EFVDDITT 1505

Query: 563  KKGDIDNVKSPEETEKD-----KNETENDSKDAEKNREEFEDQSLEKDS----------- 606
            ++   D+V+   E+E       K  T   S  +++ ++E    S E++            
Sbjct: 1506 RREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSA 1565

Query: 607  -DDKTPDDDPEQGKSEVGDFKSEKSNGELSESPGAGKGASGSTRIITR 653
             +D +  +D E  ++++ +  S   + +  E+ G GK  +G  R +TR
Sbjct: 1566 DEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTR 1613



 Score = 33.1 bits (74), Expect = 4.1
 Identities = 30/116 (25%), Positives = 40/116 (34%), Gaps = 28/116 (24%)

Query: 7   RPPKQ---PAAPAAERCAPAPPPP-----------------PPPPTSGPI-------GGL 39
           +PP Q   PA P  ++  PA PPP                 PPP   GP        G  
Sbjct: 468 KPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGST 527

Query: 40  RSRHRGSSRGRWAAAQAEVA-PKTRLSSPRGGSSSRRKPPPPPPAPPSTSAPGRGG 94
           +   +     + +A Q   A P  + S+     +   KP  PP   PS   P   G
Sbjct: 528 KPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQG 583



 Score = 32.7 bits (73), Expect = 5.4
 Identities = 22/91 (24%), Positives = 35/91 (38%), Gaps = 9/91 (9%)

Query: 7   RPPKQPAA---PAAERCAPAPPPPPPP----PTSGPIGGLRSRHRGSSRGRWAAAQAEVA 59
           +PP QP+    P A++     PP  PP    P + P+G   ++      G    +  +  
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLG--PAKPPAQQTGSEKPSSEQPG 387

Query: 60  PKTRLSSPRGGSSSRRKPPPPPPAPPSTSAP 90
           PK     P  G +  ++P P  P       P
Sbjct: 388 PKALAQPPGVGKTPAQQPGPAKPPTQQVGTP 418



 Score = 32.0 bits (71), Expect = 9.2
 Identities = 13/25 (52%), Positives = 13/25 (52%)

Query: 11   QPAAPAAERCAPAPPPPPPPPTSGP 35
            QP  P      P PPPPPPPP   P
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLP 2428


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 78.6 bits (192), Expect = 9e-14
 Identities = 144/629 (22%), Positives = 229/629 (36%), Gaps = 83/629 (13%)

Query: 2137 PPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQL 2196
            PP PQQ    L   Q         G+Q        Q Q   Q Q  PQ V   P   Q  
Sbjct: 2514 PPPPQQPPPPLPQPQAA-------GSQPPAGPPAVQPQPQPQPQTQPQPVQA-PAKAQPA 2565

Query: 2197 M----QAAMPNGTVQRFLF-TPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQ 2251
            +     AA+  GT++  +  T + T A + +    T++   A T +    +L+  +    
Sbjct: 2566 ITTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGA 2625

Query: 2252 DKT---LPPAQSSSVGP---AEAQPQTAQPSAQPQPQTQP-------------------- 2285
              T     PAQ     P   A   P TA P       TQ                     
Sbjct: 2626 LTTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTPV 2685

Query: 2286 QSPAQ---PEVQTQPEVQT--QTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSP 2340
            Q+PA+   P+V     VQ   +T   +H     Q    Q  + Q   Q Q Q   Q Q  
Sbjct: 2686 QTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQ 2745

Query: 2341 VRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSS 2400
             +  + SQ ++        SP Q   V   T + +       LQ+P Q  P   PQ QS+
Sbjct: 2746 QQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPP---PQAQSA 2802

Query: 2401 TQTLSSGQTLNQVTVSSPSRPQLQIQQ------PQPQVIAVPQLQQQVQV-------LSQ 2447
                   Q   QV V +   PQ Q  Q      P+P  +        +QV        SQ
Sbjct: 2803 PP-----QPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVARLTRVPTSQ 2857

Query: 2448 IQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQL 2507
            +Q+Q   Q QA Q   P Q+ L  P  +   +AV +      + +  A +   + + Q+ 
Sbjct: 2858 LQAQGQMQTQAPQ---PAQVALAKPPVVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKA 2914

Query: 2508 RDQ----QQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAERE 2563
              Q    Q    QQ +++K+    QA  Q + IQ Q      AV + +  ++  TP  ++
Sbjct: 2915 AGQTVVAQPVHMQQLLKLKQ----QAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQ 2970

Query: 2564 ENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSK--QNATKLSAL--LFKHK 2619
            +           +++   I + +K A  ++ + +    K  +  Q  T ++++  +    
Sbjct: 2971 KVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQVASAS 3030

Query: 2620 EQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPA 2679
            +Q   + +          Q+++   +    ++ ++K + Q    TA A    P  P P  
Sbjct: 3031 QQASPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQVVTTASAPLQTPGAPNPAQ 3090

Query: 2680 PPAPPPSPPPPPAVQ---HTGLLSTPTLP 2705
             PA   SP   P +Q       L TPT P
Sbjct: 3091 VPASSDSPSQQPKLQMRVPAVRLKTPTKP 3119



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 122/504 (24%), Positives = 190/504 (37%), Gaps = 86/504 (17%)

Query: 2092 VMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQ 2151
            V+   I G P +T  S    ++S     +LT+   ++  Q   +QPP    G        
Sbjct: 2597 VIVNTIAGVPAATFQSINKRLASPVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPD 2656

Query: 2152 LTQLTQGHGGNQGLTVVIQGQGQT------TGQLQLIPQ----------GVTVLPG---- 2191
            L  +    G     +V       T      T    L+PQ          G T+ P     
Sbjct: 2657 LVSMATTQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQL 2716

Query: 2192 ------PGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGE-QRQSKLS 2244
                    QQ  Q        Q+        T TT+      +   A    + +   KL+
Sbjct: 2717 LRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLT 2776

Query: 2245 PQMQVHQDK---TLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQT 2301
            P+  +   K    +PP       P +AQ    QP+AQ Q QT     +QP  Q  P++  
Sbjct: 2777 PEHLIKMQKQKLQMPPQPP----PPQAQSAPPQPTAQVQVQT-----SQPPQQQSPQL-- 2825

Query: 2302 QTTVSSHVPSEAQPTHAQSSKPQVAAQSQ-PQSNVQGQSPVRVQSPSQTRIRPSTPSQL- 2359
             TTV++  P  A  T    +  QVA  ++ P S +Q Q  ++ Q+P   ++  + P  + 
Sbjct: 2826 -TTVTAPRPG-ALLTGTTVANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPPVVS 2883

Query: 2360 -------SPG------------------QQSQVQTTTSQPIPIQPHTSL-QIPSQGQPQS 2393
                   SPG                  Q++  QT  +QP+ +Q    L Q   Q Q   
Sbjct: 2884 VPAAVVSSPGVTTLPMNVAGISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAI 2943

Query: 2394 QPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQP--QPQVIAVPQLQ-QQVQVLSQIQS 2450
            QPQ       +    T  Q+T     +      QP  + Q +  P  Q Q++    Q+Q+
Sbjct: 2944 QPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPISQAQKLAGAQQVQT 3003

Query: 2451 QVVAQIQAQQSGVPQQIKLQLPI-QIQQ-SSAVQTHQIQNVVTVQAASVQEQLQRVQQL- 2507
            Q+      Q + +PQ ++ Q P+  IQQ +SA Q    Q V   QA +  +Q+Q +  + 
Sbjct: 3004 QI------QVAKLPQVVQQQTPVASIQQVASASQQASPQTVALTQATAAGQQVQMIPAVT 3057

Query: 2508 ---RDQQQKKKQQQIEIKREHTLQ 2528
               +  QQK  QQQ+       LQ
Sbjct: 3058 ATAQVVQQKLIQQQVVTTASAPLQ 3081



 Score = 70.1 bits (170), Expect = 3e-11
 Identities = 75/297 (25%), Positives = 117/297 (39%), Gaps = 36/297 (12%)

Query: 2245 PQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQS---PAQPEVQTQPEVQT 2301
            PQ Q       PP        A +QP    P+ QPQPQ QPQ+   P Q   + QP + T
Sbjct: 2509 PQPQPPPPPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITT 2568

Query: 2302 -------QTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPS 2354
                     T+ + V   + PT A S    V       + + G      QS ++    P 
Sbjct: 2569 GGSAAVLAGTIKTSVTGTSMPTGAVSGNVIV-------NTIAGVPAATFQSINKRLASPV 2621

Query: 2355 TPSQL-SPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQ------SQPQVQSSTQTLSSG 2407
             P  L +PG  +  Q   +QP    P  ++  P+   P       +Q     ++ T S+ 
Sbjct: 2622 APGALTTPGGSAPAQVVHTQP----PPRAVGSPATATPDLVSMATTQGVRAVTSVTASAV 2677

Query: 2408 QTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQI 2467
             T N   V +P+R  +      PQV     +Q   + ++    Q++ Q Q QQ    QQ 
Sbjct: 2678 VTTNLTPVQTPARSLV------PQVSQATGVQLPGKTITPAHFQLLRQQQQQQQ--QQQQ 2729

Query: 2468 KLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKRE 2524
            + Q   Q QQ    Q  Q      VQ   +Q Q Q   Q++   +   +  I+++++
Sbjct: 2730 QQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQ 2786



 Score = 60.8 bits (146), Expect = 2e-08
 Identities = 123/513 (23%), Positives = 199/513 (38%), Gaps = 91/513 (17%)

Query: 1850 TPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKA 1909
            TP +TP            R   P+  + TG  +    +     +L   +   ++ ++++ 
Sbjct: 2683 TPVQTPA-----------RSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQ 2731

Query: 1910 QAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTK 1969
            Q  +QQ +++ +QQ+     T+TTS             +V V  I G   +  ++    K
Sbjct: 2732 QQQQQQQQQQQQQQQ----QTTTTS-------------QVQVPQIQGQAQSPAQIKAVGK 2774

Query: 1970 VGSPATVTFQQNKNFHQTFATWVKQGQS--NSGVVQVQQKVLGIIPSSTGTSQQTFTSFQ 2027
            + +P  +   Q +           Q QS       QVQ      + +S    QQ+     
Sbjct: 2775 L-TPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQ------VQTSQPPQQQS----- 2822

Query: 2028 PRTATVTI-RPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQP 2086
            P+  TVT  RP    +G T +N QV           + R P  Q       ++    +Q 
Sbjct: 2823 PQLTTVTAPRPGALLTGTTVANLQV---------ARLTRVPTSQ-------LQAQGQMQT 2866

Query: 2087 GAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQV- 2145
             APQ    Q+   +P    VS P  V S+PG  +L    + + I  +  QP +     V 
Sbjct: 2867 QAPQP--AQVALAKP--PVVSVPAAVVSSPGVTTL--PMNVAGISVAIGQPQKAAGQTVV 2920

Query: 2146 --KLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPN 2203
               + M QL +L Q     Q        QG    Q ++  Q +T  PG  Q++  AA P 
Sbjct: 2921 AQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITT-PGAQQKVAYAAQPA 2979

Query: 2204 GTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSV 2263
               Q FL TP++     A                Q Q +++   QV Q +T P A    V
Sbjct: 2980 LKTQ-FLTTPISQAQKLAGAQQV-----------QTQIQVAKLPQVVQQQT-PVASIQQV 3026

Query: 2264 GPA--EAQPQTA----QPSAQPQPQTQPQSPAQPEVQTQPEVQTQ--TTVSSHVPSEAQP 2315
              A  +A PQT       +A  Q Q  P   A  +V  Q  +Q Q  TT S+ + +   P
Sbjct: 3027 ASASQQASPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQVVTTASAPLQTPGAP 3086

Query: 2316 THAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQ 2348
              AQ      +   QP+  ++  + VR+++P++
Sbjct: 3087 NPAQVPASSDSPSQQPKLQMRVPA-VRLKTPTK 3118



 Score = 55.5 bits (132), Expect = 8e-07
 Identities = 61/239 (25%), Positives = 104/239 (43%), Gaps = 22/239 (9%)

Query: 2272 TAQPSAQPQPQTQPQSPAQPEVQ--TQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQS 2329
            +A P+A+P       S     VQ   +PE +T    S+H P  A PT A S+ PQ   + 
Sbjct: 1409 SAAPAARPAAAKLKASRLFQPVQYGQKPEGRTVAFPSTHPPRTAAPTTA-SAAPQGPLRG 1467

Query: 2330 QPQSNVQGQSPVR--VQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPS 2387
            +P       +P      +P QT    ++  +  P   S    + + P  ++  T+ Q  +
Sbjct: 1468 RPPIATFSANPEAKAAAAPFQTSQASASAPRHQPASASSTAASPAHPAKLRAQTTAQAST 1527

Query: 2388 QGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQ 2447
             GQP  QPQ  S     ++GQ+     +  PS  Q Q + P  +V+ + QL       S+
Sbjct: 1528 PGQPPPQPQAPSH----AAGQSALPQRLVLPS--QAQARLPSGEVVKIAQLASITGPQSR 1581

Query: 2448 I---QSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQ-NVVTVQAASVQEQLQ 2502
            +   ++ V  Q Q  +  +          Q++Q +A Q  Q+Q +V+ + +A  Q  L+
Sbjct: 1582 VAQPETPVTLQFQGSKFTLSHS-------QLRQLTAGQPLQLQGSVLQIVSAPGQPYLR 1633



 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 68/257 (26%), Positives = 103/257 (40%), Gaps = 42/257 (16%)

Query: 2210 LFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGP---- 2265
            LF P+         T    ST    T     +  +PQ  +   +  PP  + S  P    
Sbjct: 1426 LFQPVQYGQKPEGRTVAFPSTHPPRTAAPTTASAAPQGPL---RGRPPIATFSANPEAKA 1482

Query: 2266 AEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQV 2325
            A A  QT+Q SA   P+ QP S                  SS   S A P        ++
Sbjct: 1483 AAAPFQTSQASASA-PRHQPAS-----------------ASSTAASPAHPA-------KL 1517

Query: 2326 AAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQI 2385
             AQ+  Q++  GQ P + Q+PS    + + P +L    Q+Q +  + + + I    S+  
Sbjct: 1518 RAQTTAQASTPGQPPPQPQAPSHAAGQSALPQRLVLPSQAQARLPSGEVVKIAQLASITG 1577

Query: 2386 PSQ--GQPQSQP--QVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQ 2441
            P     QP++    Q Q S  TLS  Q L Q+T   P    LQ+Q    Q+++ P  Q  
Sbjct: 1578 PQSRVAQPETPVTLQFQGSKFTLSHSQ-LRQLTAGQP----LQLQGSVLQIVSAPG-QPY 1631

Query: 2442 VQVLSQIQSQVVAQIQA 2458
            ++    +  Q V+Q  A
Sbjct: 1632 LRAPGPVVMQTVSQAGA 1648



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 45/148 (30%), Positives = 63/148 (42%), Gaps = 14/148 (9%)

Query: 2340 PVRVQSPSQTRIRPSTP--SQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQV 2397
            P++   P+     P TP  +QL+  +QSQ Q   S   P+Q   SL  P    P   P  
Sbjct: 504  PLQQLMPTAQGGMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPA 563

Query: 2398 QSSTQTLSSGQTLNQVTVSSPSRPQLQI----QQPQPQVIAVPQLQ------QQVQVLSQ 2447
               T  LSS     Q      ++ QLQI    QQP   + A P  Q      Q  Q+   
Sbjct: 564  GVPTAALSSALQFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALH 623

Query: 2448 IQSQVVAQIQAQQ-SGVPQQI-KLQLPI 2473
            + +    Q+QA Q S +PQ +   +LP+
Sbjct: 624  VPTPGKVQVQASQLSSLPQMVASTRLPV 651



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 35/117 (29%), Positives = 50/117 (42%), Gaps = 5/117 (4%)

Query: 2619 KEQLRAEILKKRAL-LDKDLQIEVQEELKRDLKIKKEKDLM---QLAQATAVAAPCPPVT 2674
            K    A +L +  +  DK L   +Q    R  +I KEK  +   Q AQ  AVA P PP  
Sbjct: 2453 KNPKHASVLAESGINYDKPLP-PIQVASLRAERIAKEKKALADQQKAQQPAVAQPPPPQP 2511

Query: 2675 PAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMIST 2731
              PP P  PPP  P P A         P +    Q + + + +   + +K +  I+T
Sbjct: 2512 QPPPPPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITT 2568



 Score = 41.2 bits (95), Expect = 0.015
 Identities = 94/445 (21%), Positives = 169/445 (37%), Gaps = 73/445 (16%)

Query: 2141 QQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQ--LQLIPQGVTVLPGPGQQLMQ 2198
            QQ      MA+ ++  +   G+QG  VV Q  G   G    QL+P     +P P  Q  Q
Sbjct: 468  QQAMPSTGMAEQSKRPRLEVGHQG--VVFQHPGADAGVPLQQLMPTAQGGMP-PTPQAAQ 524

Query: 2199 AAMPNGTVQRF--LFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLP 2256
             A    + Q++     P    A +  T    +       G    + LS  +Q  Q   + 
Sbjct: 525  LAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAA-LSSALQFAQQPQV- 582

Query: 2257 PAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPT 2316
                      EAQ Q   P    QP     +P   ++   P    Q  +    P + Q  
Sbjct: 583  ---------VEAQTQLQIPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQ 633

Query: 2317 HAQ-SSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPI 2375
             +Q SS PQ+ A +        + PV    P    +  S+ S L+P        + S P 
Sbjct: 634  ASQLSSLPQMVAST--------RLPVDPAPPCPRPLPTSSTSSLAP-------VSGSGPG 678

Query: 2376 PIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQ-PQPQVIA 2434
            P         P++  P ++P   ++            V  S+P++PQ   Q     Q  +
Sbjct: 679  P--------SPARSSPVNRPSSATNKALSPVTSRTPGVVASAPTKPQSPAQNATSSQDSS 730

Query: 2435 VPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQA 2494
               L +Q+ + +Q+  ++    + +++G+  Q +L    +  +  +   + ++ +  +  
Sbjct: 731  QDTLTEQITLENQVHQRIA---ELRKAGLWSQRRLPKLQEAPRPKSHWDYLLEEMQWMAT 787

Query: 2495 ASVQEQLQRV----------------QQLRDQQQKKKQQQIEIKREHTLQASNQSEI--- 2535
               QE+  +V                +QLR+++ KK++Q     R   + AS   EI   
Sbjct: 788  DFAQERRWKVAAAKKLVRTVVRHHEEKQLREERGKKEEQ----SRLRRIAASTAREIECF 843

Query: 2536 ---IQKQVVMKHNAVIEHLKQKKSM 2557
               I++ V +K    +E  K+KK++
Sbjct: 844  WSNIEQVVEIKLRVELEE-KRKKAL 867



 Score = 39.3 bits (90), Expect = 0.058
 Identities = 61/261 (23%), Positives = 96/261 (36%), Gaps = 35/261 (13%)

Query: 2234 GTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEV 2293
            GTG Q     + Q Q+ + +  P +        E + Q A P+  P P       A P  
Sbjct: 4    GTGPQ-----NVQHQLQRSRACPGS--------EGEEQPAHPNPPPSPAAPFAPSASPSA 50

Query: 2294 QTQPEVQTQTTVSSHVPSEAQPTH--AQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRI 2351
               P  Q Q  + +  P+  Q  +   QS  P V    Q        +P+ + SP+    
Sbjct: 51   PQSPSYQIQ-QLMNRSPATGQNVNITLQSVGPVVGGNQQIT-----LAPLPLPSPTSPGF 104

Query: 2352 RPST-PSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTL 2410
            + S  P +   G  S +Q T+     +Q  +  Q PS G  Q+   V++       G   
Sbjct: 105  QFSAQPRRFEHGSPSYIQVTSPLSQQVQTQSPTQ-PSPGPGQALQNVRAGAPGPGLG--- 160

Query: 2411 NQVTVSSPSRPQLQIQQPQPQVIAVPQ-----LQQQVQVLSQIQSQVVAQIQAQQSGVPQ 2465
              +  SSP+   +       Q+   P      + Q    L+QI     AQ+Q Q  G P 
Sbjct: 161  --LCSSSPTGGFVDASVLVRQISLSPSSGGHFVFQDGSGLTQIAQG--AQVQLQHPGTPI 216

Query: 2466 QIKLQLPIQIQQSSAVQTHQI 2486
             ++ + P Q    S    H +
Sbjct: 217  TVRERRPSQPHTQSGGTIHHL 237



 Score = 35.8 bits (81), Expect = 0.64
 Identities = 77/346 (22%), Positives = 131/346 (37%), Gaps = 59/346 (17%)

Query: 1993 KQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVI 2052
            ++ +  S V+  +Q + G + +  G++ +T   F+ + A     P+T G    +   ++ 
Sbjct: 433  EEEEEKSEVINDEQALAGSLVAGAGSTVET-DLFKRQQAM----PST-GMAEQSKRPRLE 486

Query: 2053 TGPQ----IRPGMTVIRTPLQQ--STLGKAIIRTPVMVQPGAPQQVMTQI--IRGQPVST 2104
             G Q      PG      PLQQ   T    +  TP   Q    +Q   Q     G PV  
Sbjct: 487  VGHQGVVFQHPGADA-GVPLQQLMPTAQGGMPPTPQAAQLAGQRQSQQQYDPSTGPPVQN 545

Query: 2105 AVSAPNTVSSTPGQ---KSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGG 2161
            A S    +   PG+     + +A  +S +Q +  Q P+  + Q +L +   TQ       
Sbjct: 546  AASLHTPLPQLPGRLPPAGVPTAALSSALQFA--QQPQVVEAQTQLQIPVKTQQPN---- 599

Query: 2162 NQGLTVVIQGQGQTTGQLQLIPQGVTVL----PGPGQQLMQAAMPNGTVQRFLFTPLATT 2217
                   +      + QL + P     L    P PG+  +QA+  +   Q    T L   
Sbjct: 600  -------VPIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQASQLSSLPQMVASTRLPVD 652

Query: 2218 A---------TTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEA 2268
                      T+++++   VS +  G    R S ++       +K L P  S + G   +
Sbjct: 653  PAPPCPRPLPTSSTSSLAPVSGSGPGPSPARSSPVNRPSSA-TNKALSPVTSRTPGVVAS 711

Query: 2269 QPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQ 2314
             P            T+PQSPAQ    +Q    +Q T++  +  E Q
Sbjct: 712  AP------------TKPQSPAQNATSSQD--SSQDTLTEQITLENQ 743


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.125    0.352 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 122,211,210
Number of Sequences: 37866
Number of extensions: 6747079
Number of successful extensions: 176794
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1439
Number of HSP's successfully gapped in prelim test: 2628
Number of HSP's that attempted gapping in prelim test: 57217
Number of HSP's gapped (non-prelim): 75817
length of query: 2920
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2800
effective length of database: 13,703,598
effective search space: 38370074400
effective search space used: 38370074400
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 71 (32.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.