Guide to the Human Genome
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Search of human proteins with 38524612

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38524612 tripartite motif-containing 74 [Homo sapiens]
         (250 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38524612 tripartite motif-containing 74 [Homo sapiens]             523   e-149
gi|65285121 tripartite motif-containing 73 [Homo sapiens]             517   e-147
gi|30023818 tripartite motif protein 50A [Homo sapiens]               478   e-135
gi|56605981 tripartite motif-containing 72 [Homo sapiens]             108   4e-24
gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens]     104   6e-23
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]      104   6e-23
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]      104   6e-23
gi|51477690 tripartite motif-containing 6 and tripartite motif-c...   104   6e-23
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   100   9e-22
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   100   9e-22
gi|117938316 tripartite motif-containing 22 [Homo sapiens]            100   1e-21
gi|5730009 ret finger protein [Homo sapiens]                          100   1e-21
gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s...   100   2e-21
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]     97   1e-20
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]     97   1e-20
gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo s...    97   1e-20
gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo s...    97   1e-20
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa...    95   7e-20
gi|22749269 ring finger protein 129 [Homo sapiens]                     93   2e-19
gi|60099474 tripartite motif-containing 61 [Homo sapiens]              89   3e-18
gi|27436877 tripartite motif-containing 59 [Homo sapiens]              89   3e-18
gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens]    89   3e-18
gi|198442878 tripartite motif-containing 17 isoform 3 [Homo sapi...    88   6e-18
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]    88   6e-18
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]     88   6e-18
gi|21630277 tripartite motif-containing 11 [Homo sapiens]              88   6e-18
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]     88   8e-18
gi|55953112 ret finger protein 2 isoform 2 [Homo sapiens]              87   1e-17
gi|47132524 ret finger protein 2 isoform 1 [Homo sapiens]              87   1e-17
gi|16445412 ret finger protein 2 isoform 1 [Homo sapiens]              87   1e-17

>gi|38524612 tripartite motif-containing 74 [Homo sapiens]
          Length = 250

 Score =  523 bits (1346), Expect = e-149
 Identities = 250/250 (100%), Positives = 250/250 (100%)

Query: 1   MAWQVSLLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV 60
           MAWQVSLLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV
Sbjct: 1   MAWQVSLLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV 60

Query: 61  DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH 120
           DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH
Sbjct: 61  DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH 120

Query: 121 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ 180
           PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ
Sbjct: 121 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ 180

Query: 181 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF 240
           ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF
Sbjct: 181 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF 240

Query: 241 IWKFHSMASR 250
           IWKFHSMASR
Sbjct: 241 IWKFHSMASR 250


>gi|65285121 tripartite motif-containing 73 [Homo sapiens]
          Length = 250

 Score =  517 bits (1332), Expect = e-147
 Identities = 249/250 (99%), Positives = 249/250 (99%)

Query: 1   MAWQVSLLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV 60
           MAWQVSLLELED LQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV
Sbjct: 1   MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV 60

Query: 61  DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH 120
           DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH
Sbjct: 61  DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH 120

Query: 121 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ 180
           PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ
Sbjct: 121 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ 180

Query: 181 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF 240
           ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF
Sbjct: 181 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF 240

Query: 241 IWKFHSMASR 250
           IWKFHSMASR
Sbjct: 241 IWKFHSMASR 250


>gi|30023818 tripartite motif protein 50A [Homo sapiens]
          Length = 487

 Score =  478 bits (1229), Expect = e-135
 Identities = 234/250 (93%), Positives = 238/250 (95%)

Query: 1   MAWQVSLLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV 60
           MAWQVSLLELEDWLQCPICLEVFKE LMLQCGHSYCKGCLVSLS HLD ++RCP+C Q V
Sbjct: 1   MAWQVSLLELEDWLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAV 60

Query: 61  DGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH 120
           DGSSSLPNVSLA VIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH
Sbjct: 61  DGSSSLPNVSLARVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHH 120

Query: 121 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ 180
           PVTPVSTV SRMKEELAAL SELKQEQKKVDELIAKLV NRTRIVNESDVFSWVIRREFQ
Sbjct: 121 PVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVIRREFQ 180

Query: 181 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF 240
           EL H VDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHH+F
Sbjct: 181 ELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHKF 240

Query: 241 IWKFHSMASR 250
           I KFHSMASR
Sbjct: 241 IRKFHSMASR 250


>gi|56605981 tripartite motif-containing 72 [Homo sapiens]
          Length = 477

 Score =  108 bits (270), Expect = 4e-24
 Identities = 72/250 (28%), Positives = 118/250 (47%), Gaps = 19/250 (7%)

Query: 10  LEDWLQCPICLEVFKESLMLQCGHSYCKGCL--VSLSYHLDTKVRCPMCWQVVDGSSSLP 67
           L   L CP+CL++F   +  +CGHS+C+ CL  V+     D  V CP C       +   
Sbjct: 8   LHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALST 67

Query: 68  NVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHHPVTPVST 127
           N+ LA ++E L          C  H +PLS++CE+D+ L+CG+C  LGSH+ H + P + 
Sbjct: 68  NLQLARLVEGLAQVPQGH---CEEHLDPLSIYCEQDRALVCGVCASLGSHRGHRLLPAAE 124

Query: 128 VCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQELR---- 183
             +R+K +L     +L++   + ++ +A L      +      F   +  +  ++R    
Sbjct: 125 AHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMRVFLA 184

Query: 184 ---HPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEF 240
                +D E  R     G   R  + SL+  LEQ       L Q E VLE+  ++   EF
Sbjct: 185 ALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQ-------LRQMEKVLEEVADKPQTEF 237

Query: 241 IWKFHSMASR 250
           + K+  + SR
Sbjct: 238 LMKYCLVTSR 247


>gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens]
          Length = 270

 Score =  104 bits (260), Expect = 6e-23
 Identities = 69/234 (29%), Positives = 114/234 (48%), Gaps = 13/234 (5%)

Query: 7   LLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDT----KVRCPMCWQVVDG 62
           LL +++ + CPICLE+  E L L CGHS C+ C+   +    T    K  CP+C      
Sbjct: 6   LLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSF 65

Query: 63  SSSLPNVSLAWVIEALR---LPGDPEPK--VCVHHRNPLSLFCEKDQELICGLCGLLGSH 117
                N  LA ++E L+   L  D   K  +C HH   L LFC++D+++IC LC     H
Sbjct: 66  EHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEH 125

Query: 118 QHHPVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRR 177
           + H       V    +E+L A+   LK+E+++ ++L A + + +T    +       I+ 
Sbjct: 126 RGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQT 185

Query: 178 EFQELRHPVDEEKARCLEGIGGHTRGLVASL----DMQLEQAQGTRERLAQAEC 227
           EF +LR  ++ E+ R L+ +    +  +       D  ++Q Q  RE ++  EC
Sbjct: 186 EFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVEC 239


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  104 bits (260), Expect = 6e-23
 Identities = 69/234 (29%), Positives = 114/234 (48%), Gaps = 13/234 (5%)

Query: 7   LLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDT----KVRCPMCWQVVDG 62
           LL +++ + CPICLE+  E L L CGHS C+ C+   +    T    K  CP+C      
Sbjct: 6   LLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSF 65

Query: 63  SSSLPNVSLAWVIEALR---LPGDPEPK--VCVHHRNPLSLFCEKDQELICGLCGLLGSH 117
                N  LA ++E L+   L  D   K  +C HH   L LFC++D+++IC LC     H
Sbjct: 66  EHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEH 125

Query: 118 QHHPVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRR 177
           + H       V    +E+L A+   LK+E+++ ++L A + + +T    +       I+ 
Sbjct: 126 RGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQT 185

Query: 178 EFQELRHPVDEEKARCLEGIGGHTRGLVASL----DMQLEQAQGTRERLAQAEC 227
           EF +LR  ++ E+ R L+ +    +  +       D  ++Q Q  RE ++  EC
Sbjct: 186 EFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVEC 239


>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  104 bits (260), Expect = 6e-23
 Identities = 69/234 (29%), Positives = 114/234 (48%), Gaps = 13/234 (5%)

Query: 7   LLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDT----KVRCPMCWQVVDG 62
           LL +++ + CPICLE+  E L L CGHS C+ C+   +    T    K  CP+C      
Sbjct: 6   LLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSF 65

Query: 63  SSSLPNVSLAWVIEALR---LPGDPEPK--VCVHHRNPLSLFCEKDQELICGLCGLLGSH 117
                N  LA ++E L+   L  D   K  +C HH   L LFC++D+++IC LC     H
Sbjct: 66  EHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEH 125

Query: 118 QHHPVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRR 177
           + H       V    +E+L A+   LK+E+++ ++L A + + +T    +       I+ 
Sbjct: 126 RGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQT 185

Query: 178 EFQELRHPVDEEKARCLEGIGGHTRGLVASL----DMQLEQAQGTRERLAQAEC 227
           EF +LR  ++ E+ R L+ +    +  +       D  ++Q Q  RE ++  EC
Sbjct: 186 EFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVEC 239


>gi|51477690 tripartite motif-containing 6 and tripartite
           motif-containing 34 [Homo sapiens]
          Length = 842

 Score =  104 bits (260), Expect = 6e-23
 Identities = 69/234 (29%), Positives = 114/234 (48%), Gaps = 13/234 (5%)

Query: 7   LLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDT----KVRCPMCWQVVDG 62
           LL +++ + CPICLE+  E L L CGHS C+ C+   +    T    K  CP+C      
Sbjct: 360 LLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSF 419

Query: 63  SSSLPNVSLAWVIEALR---LPGDPEPK--VCVHHRNPLSLFCEKDQELICGLCGLLGSH 117
                N  LA ++E L+   L  D   K  +C HH   L LFC++D+++IC LC     H
Sbjct: 420 EHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEH 479

Query: 118 QHHPVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRR 177
           + H       V    +E+L A+   LK+E+++ ++L A + + +T    +       I+ 
Sbjct: 480 RGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQT 539

Query: 178 EFQELRHPVDEEKARCLEGIGGHTRGLVASL----DMQLEQAQGTRERLAQAEC 227
           EF +LR  ++ E+ R L+ +    +  +       D  ++Q Q  RE ++  EC
Sbjct: 540 EFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVEC 593



 Score = 97.1 bits (240), Expect = 1e-20
 Identities = 58/198 (29%), Positives = 98/198 (49%), Gaps = 9/198 (4%)

Query: 7   LLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHL----DTKVRCPMCWQVVDG 62
           L+++ + + CPICLE+  E L + CGHS+C+ C+           + +  CP+C      
Sbjct: 34  LVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQP 93

Query: 63  SSSLPNVSLAWVIEALRL----PGDPEPKV-CVHHRNPLSLFCEKDQELICGLCGLLGSH 117
            +  PN  LA ++  LR     PG     V C  H   L LFC++D ++IC LC     H
Sbjct: 94  GNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEH 153

Query: 118 QHHPVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRR 177
           + H    V  V    +E+      +LK E+++ ++L A + + +T   N+ +     I+ 
Sbjct: 154 RGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQT 213

Query: 178 EFQELRHPVDEEKARCLE 195
           EF +LR+ +D  + R L+
Sbjct: 214 EFNQLRNILDRVEQRELK 231


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  100 bits (250), Expect = 9e-22
 Identities = 61/230 (26%), Positives = 103/230 (44%), Gaps = 5/230 (2%)

Query: 6   SLLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVVDGSSS 65
           +L  L+    C +CLE  KE ++++CGH++CK C+      L+    CP+C +     S 
Sbjct: 19  ALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSL 78

Query: 66  LPNVSLAWVIEALRLPGDPEPKV-----CVHHRNPLSLFCEKDQELICGLCGLLGSHQHH 120
            PN  L  ++E  +     + K+     C  H   LSLFC +DQE +C +C +  +H+ H
Sbjct: 79  RPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAH 138

Query: 121 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ 180
            V P+       KE+L      L+Q+ +++    +   K    +    +     I REF+
Sbjct: 139 TVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFE 198

Query: 181 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLE 230
           EL   +DEE+   L  +    + ++  L          R  LA     +E
Sbjct: 199 ELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVE 248


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  100 bits (250), Expect = 9e-22
 Identities = 61/230 (26%), Positives = 103/230 (44%), Gaps = 5/230 (2%)

Query: 6   SLLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVVDGSSS 65
           +L  L+    C +CLE  KE ++++CGH++CK C+      L+    CP+C +     S 
Sbjct: 19  ALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSL 78

Query: 66  LPNVSLAWVIEALRLPGDPEPKV-----CVHHRNPLSLFCEKDQELICGLCGLLGSHQHH 120
            PN  L  ++E  +     + K+     C  H   LSLFC +DQE +C +C +  +H+ H
Sbjct: 79  RPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAH 138

Query: 121 PVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQ 180
            V P+       KE+L      L+Q+ +++    +   K    +    +     I REF+
Sbjct: 139 TVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFE 198

Query: 181 ELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLE 230
           EL   +DEE+   L  +    + ++  L          R  LA     +E
Sbjct: 199 ELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVE 248


>gi|117938316 tripartite motif-containing 22 [Homo sapiens]
          Length = 498

 Score =  100 bits (249), Expect = 1e-21
 Identities = 65/222 (29%), Positives = 108/222 (48%), Gaps = 13/222 (5%)

Query: 8   LELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVR----CPMCWQVVDGS 63
           +++E  + CPICLE+  E L L CGHS+C+ C+ +         R    CP+C       
Sbjct: 7   VDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPG 66

Query: 64  SSLPNVSLAWVIEALR----LPGDPEPK-VCVHHRNPLSLFCEKDQELICGLCGLLGSHQ 118
           +  PN  LA ++E ++     P + + + VC HH   L +FC++D ++IC +C L   HQ
Sbjct: 67  NLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCELSQEHQ 126

Query: 119 HHPVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRRE 178
            H    ++ V    +E+L      L +E ++ ++L   + + RT   N   +    I + 
Sbjct: 127 GHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQKILKG 186

Query: 179 FQELRHPVDEEKARCL----EGIGGHTRGLVASLDMQLEQAQ 216
           F E+R  +D E+ R L    EG       L A+ D  ++Q Q
Sbjct: 187 FNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQ 228


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  100 bits (249), Expect = 1e-21
 Identities = 68/248 (27%), Positives = 107/248 (43%), Gaps = 7/248 (2%)

Query: 10  LEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVVDGSSSLPNV 69
           L+    CP+CL+ F E +ML CGH+ C  CL       +T V CP C +        PN 
Sbjct: 10  LQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMRPNR 69

Query: 70  SLAWVIEALR-----LPGDP--EPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHHPV 122
            LA V + ++      P  P  E  VC  HR PL L+CE+DQ  IC +C     H+ H V
Sbjct: 70  HLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHSV 129

Query: 123 TPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQEL 182
            P+       KE++      LK+ +       A+  + R  +++ + +    I  EF++L
Sbjct: 130 LPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQL 189

Query: 183 RHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEFIW 242
            H + E + R L  +      +  S++  + Q       L+     LE+   +   E + 
Sbjct: 190 YHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQ 249

Query: 243 KFHSMASR 250
                 SR
Sbjct: 250 DIGDTLSR 257


>gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
           sapiens]
          Length = 493

 Score =  100 bits (248), Expect = 2e-21
 Identities = 64/231 (27%), Positives = 112/231 (48%), Gaps = 11/231 (4%)

Query: 7   LLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVS--LSYHLDT-KVRCPMCWQVVDGS 63
           L+ +++ + CPICLE+  + L L CGHS+C+ CL +      LD  +  CP+C       
Sbjct: 6   LVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPE 65

Query: 64  SSLPNVSLAWVIEALR----LPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQH 119
           +  PN  +A ++E LR     P   +   C  H   L LFC++D ++IC LC     H+ 
Sbjct: 66  NIRPNRHVANLVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQEHRG 125

Query: 120 HPVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREF 179
           H   P   V    + +L A    L+Q+Q++ +EL A + + +     +       +  +F
Sbjct: 126 HHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVLADF 185

Query: 180 QELRHPVDEEKARCLEGIGGHTRGLVASL----DMQLEQAQGTRERLAQAE 226
           ++LR  +D E++  L+ +      ++ SL       ++Q Q  RE ++  E
Sbjct: 186 EQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLE 236


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score = 97.1 bits (240), Expect = 1e-20
 Identities = 58/198 (29%), Positives = 98/198 (49%), Gaps = 9/198 (4%)

Query: 7   LLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHL----DTKVRCPMCWQVVDG 62
           L+++ + + CPICLE+  E L + CGHS+C+ C+           + +  CP+C      
Sbjct: 6   LVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQP 65

Query: 63  SSSLPNVSLAWVIEALRL----PGDPEPKV-CVHHRNPLSLFCEKDQELICGLCGLLGSH 117
            +  PN  LA ++  LR     PG     V C  H   L LFC++D ++IC LC     H
Sbjct: 66  GNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEH 125

Query: 118 QHHPVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRR 177
           + H    V  V    +E+      +LK E+++ ++L A + + +T   N+ +     I+ 
Sbjct: 126 RGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQT 185

Query: 178 EFQELRHPVDEEKARCLE 195
           EF +LR+ +D  + R L+
Sbjct: 186 EFNQLRNILDRVEQRELK 203


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score = 97.1 bits (240), Expect = 1e-20
 Identities = 58/198 (29%), Positives = 98/198 (49%), Gaps = 9/198 (4%)

Query: 7   LLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHL----DTKVRCPMCWQVVDG 62
           L+++ + + CPICLE+  E L + CGHS+C+ C+           + +  CP+C      
Sbjct: 34  LVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQP 93

Query: 63  SSSLPNVSLAWVIEALRL----PGDPEPKV-CVHHRNPLSLFCEKDQELICGLCGLLGSH 117
            +  PN  LA ++  LR     PG     V C  H   L LFC++D ++IC LC     H
Sbjct: 94  GNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEH 153

Query: 118 QHHPVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRR 177
           + H    V  V    +E+      +LK E+++ ++L A + + +T   N+ +     I+ 
Sbjct: 154 RGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQT 213

Query: 178 EFQELRHPVDEEKARCLE 195
           EF +LR+ +D  + R L+
Sbjct: 214 EFNQLRNILDRVEQRELK 231


>gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo
           sapiens]
          Length = 326

 Score = 97.1 bits (240), Expect = 1e-20
 Identities = 63/231 (27%), Positives = 111/231 (48%), Gaps = 11/231 (4%)

Query: 7   LLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVS--LSYHLDT-KVRCPMCWQVVDGS 63
           L+ +++ + CPICLE+  + L L CGHS+C+ CL +      LD  +  CP+C       
Sbjct: 6   LVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPE 65

Query: 64  SSLPNVSLAWVIEALR----LPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQH 119
           +  PN  +A ++E LR     P   +   C  H   L LFC++D ++IC LC     H+ 
Sbjct: 66  NIRPNRHVANIVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQEHRG 125

Query: 120 HPVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREF 179
           H       V    + +L A    L+Q+Q++ +EL A + + +     +       +  +F
Sbjct: 126 HHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVLADF 185

Query: 180 QELRHPVDEEKARCLEGIGGHTRGLVASL----DMQLEQAQGTRERLAQAE 226
           ++LR  +D E++  L+ +      ++ SL       ++Q Q  RE ++  E
Sbjct: 186 EQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLE 236


>gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo
           sapiens]
          Length = 347

 Score = 97.1 bits (240), Expect = 1e-20
 Identities = 63/231 (27%), Positives = 111/231 (48%), Gaps = 11/231 (4%)

Query: 7   LLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVS--LSYHLDT-KVRCPMCWQVVDGS 63
           L+ +++ + CPICLE+  + L L CGHS+C+ CL +      LD  +  CP+C       
Sbjct: 6   LVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPE 65

Query: 64  SSLPNVSLAWVIEALR----LPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQH 119
           +  PN  +A ++E LR     P   +   C  H   L LFC++D ++IC LC     H+ 
Sbjct: 66  NIRPNRHVANIVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQEHRG 125

Query: 120 HPVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREF 179
           H       V    + +L A    L+Q+Q++ +EL A + + +     +       +  +F
Sbjct: 126 HHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVLADF 185

Query: 180 QELRHPVDEEKARCLEGIGGHTRGLVASL----DMQLEQAQGTRERLAQAE 226
           ++LR  +D E++  L+ +      ++ SL       ++Q Q  RE ++  E
Sbjct: 186 EQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLE 236


>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
           sapiens]
          Length = 474

 Score = 94.7 bits (234), Expect = 7e-20
 Identities = 58/184 (31%), Positives = 90/184 (48%), Gaps = 2/184 (1%)

Query: 9   ELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVVDGSSSLPN 68
           ++++ L CPICL+ F++ + ++CGH++C+GCL            CP C      ++  PN
Sbjct: 5   DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPN 64

Query: 69  VSLAWVIEAL--RLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHHPVTPVS 126
            +LA + E    R  G   P +C  H  PL LFCE DQ  +C +C     HQ H + P+ 
Sbjct: 65  WALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPID 124

Query: 127 TVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQELRHPV 186
                 +E+L      L  + KKV  L    VKN T+  ++       I  EF +L + +
Sbjct: 125 EAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFL 184

Query: 187 DEEK 190
            EE+
Sbjct: 185 VEEE 188


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 56/220 (25%), Positives = 96/220 (43%), Gaps = 8/220 (3%)

Query: 1   MAWQVSLLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV 60
           M +  +L+ L++   CPICLE  K+ + + CGH++C+ CL      LD    CP+C    
Sbjct: 1   MEFVTALVNLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDDTFPCPVCRFCF 60

Query: 61  DGSS--------SLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCG 112
              S        +L  ++    I   +     E  +C  H   L+LFC KD E++C  C 
Sbjct: 61  PYKSFRRNPQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCS 120

Query: 113 LLGSHQHHPVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFS 172
               HQ H + P+    S  +E L      L+   ++V+++I         +  + +   
Sbjct: 121 FSTKHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKR 180

Query: 173 WVIRREFQELRHPVDEEKARCLEGIGGHTRGLVASLDMQL 212
             I  EF+++R  +  E+   L  I      ++A L+  L
Sbjct: 181 EEINSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENL 220


>gi|60099474 tripartite motif-containing 61 [Homo sapiens]
          Length = 209

 Score = 89.4 bits (220), Expect = 3e-18
 Identities = 51/171 (29%), Positives = 77/171 (45%), Gaps = 12/171 (7%)

Query: 1   MAWQVSLLELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVV 60
           M +  +L +L     CPICL+  K+ + + CGH++C  C++     L     CP C    
Sbjct: 1   MEFVTALADLRAEASCPICLDYLKDPVTISCGHNFCLSCIIMSWKDLHDSFPCPFCHFCC 60

Query: 61  DGSSSLPNVSLAWVIE--------ALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCG 112
                + N  L  + E        + +     E  VC  H   L+ FC+KD EL+C  C 
Sbjct: 61  PERKFISNPQLGSLTEIAKQLQIRSKKRKRQEEKHVCKKHNQVLTFFCQKDLELLCPRCS 120

Query: 113 LLGSHQHHPVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTR 163
           L   HQHH V P+    S  +++L     E     K+  ELI K++  +TR
Sbjct: 121 LSTDHQHHCVWPIKKAASYHRKKL----EEYNAPWKERVELIEKVITMQTR 167


>gi|27436877 tripartite motif-containing 59 [Homo sapiens]
          Length = 403

 Score = 89.4 bits (220), Expect = 3e-18
 Identities = 60/249 (24%), Positives = 113/249 (45%), Gaps = 16/249 (6%)

Query: 11  EDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYH---------LDTKVRCPMCWQVVD 61
           E+ L CPIC  +F++  +L C H++C+ CL ++            L   ++CP C  + +
Sbjct: 5   EEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRSITE 64

Query: 62  ----GSSSLP-NVSLAWVIEALRLPGDPEPKVCV-HHRNPLSLFCEKDQELICGLCGLLG 115
               G  SLP N +L  +IE  +    P+   C  H+R PL+++C  D++L+CG C  +G
Sbjct: 65  IAPTGIESLPVNFALRAIIEKYQQEDHPDIVTCPEHYRQPLNVYCLLDKKLVCGHCLTIG 124

Query: 116 SHQHHPVTPVSTVCSRMKEELAALFSELKQEQ-KKVDELIAKLVKNRTRIVNESDVFSWV 174
            H  HP+  + +   + K+    L  +L       +  LI KL + ++            
Sbjct: 125 QHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQGDKEA 184

Query: 175 IRREFQELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGN 234
           + + F+EL   ++++K   L  +      +      Q+E+ +  RE+  +   +      
Sbjct: 185 VLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALTISLQE 244

Query: 235 EDHHEFIWK 243
           E   +F+ K
Sbjct: 245 ESPLKFLEK 253


>gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens]
          Length = 493

 Score = 89.4 bits (220), Expect = 3e-18
 Identities = 68/249 (27%), Positives = 112/249 (44%), Gaps = 17/249 (6%)

Query: 14  LQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVVDGSSSLPNVSLAW 73
           L C +C + F++++ L+CGH++C+GC VS  + +     CP+C      +    N +L  
Sbjct: 19  LLCAVCYDPFRDAVTLRCGHNFCRGC-VSRCWEVQVSPTCPVCKDRASPADLRTNHTLNN 77

Query: 74  VIEAL--------RLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHHPVTPV 125
           ++E L        R       +VC  HR  LSLFC +D+EL+C  C     HQ H V PV
Sbjct: 78  LVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPV 137

Query: 126 STVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDV-FSWV---IRREFQE 181
                  + +   +   L+++ K        + ++   I   + V  +W+   IR+EF +
Sbjct: 138 KDTAHDFRAKCRNMEHALREKAK----AFWAMRRSYEAIAKHNQVEAAWLEGRIRQEFDK 193

Query: 182 LRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEFI 241
           LR  +  E+   L+ +   TR      D +++Q     E LA     L+    ED   F+
Sbjct: 194 LREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFL 253

Query: 242 WKFHSMASR 250
            K  S   R
Sbjct: 254 MKHKSRKRR 262


>gi|198442878 tripartite motif-containing 17 isoform 3 [Homo
           sapiens]
          Length = 343

 Score = 88.2 bits (217), Expect = 6e-18
 Identities = 65/224 (29%), Positives = 104/224 (46%), Gaps = 25/224 (11%)

Query: 9   ELEDWLQCPICLEVFKESLMLQCGHSYCKGCL-VSLSYHLDTKVR--------CPMCWQV 59
           +L++   C ICL+ F + +M  CGH++C+ C+ +S       K R        CP C ++
Sbjct: 9   KLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREM 68

Query: 60  VDGSSSLPNVSLAWVIE-ALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQ 118
               + LPN  L  V E A + PG  +  +C  H  PL LFC+KDQ  IC +C     H+
Sbjct: 69  SPQRNLLPNRLLTKVAEMAQQHPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHR 128

Query: 119 HHPVTPVSTVCS----RMKEELAALFSEL-------KQEQKKVDELIAKLVKNRTRIVNE 167
            H V P          +++E++  L  ++        +E++ + E   K+ + R RIV E
Sbjct: 129 LHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLE 188

Query: 168 SDVFSWVIRREFQELRHPVDEEKARCLEGIGGHTRGLVASLDMQ 211
            +  +  +  E Q L   ++ E+    E      R  VA LD Q
Sbjct: 189 FEKMNLYLVEEEQRLLQALETEE----EETASRLRESVACLDRQ 228


>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score = 88.2 bits (217), Expect = 6e-18
 Identities = 65/224 (29%), Positives = 104/224 (46%), Gaps = 25/224 (11%)

Query: 9   ELEDWLQCPICLEVFKESLMLQCGHSYCKGCL-VSLSYHLDTKVR--------CPMCWQV 59
           +L++   C ICL+ F + +M  CGH++C+ C+ +S       K R        CP C ++
Sbjct: 9   KLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREM 68

Query: 60  VDGSSSLPNVSLAWVIE-ALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQ 118
               + LPN  L  V E A + PG  +  +C  H  PL LFC+KDQ  IC +C     H+
Sbjct: 69  SPQRNLLPNRLLTKVAEMAQQHPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHR 128

Query: 119 HHPVTPVSTVCS----RMKEELAALFSEL-------KQEQKKVDELIAKLVKNRTRIVNE 167
            H V P          +++E++  L  ++        +E++ + E   K+ + R RIV E
Sbjct: 129 LHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLE 188

Query: 168 SDVFSWVIRREFQELRHPVDEEKARCLEGIGGHTRGLVASLDMQ 211
            +  +  +  E Q L   ++ E+    E      R  VA LD Q
Sbjct: 189 FEKMNLYLVEEEQRLLQALETEE----EETASRLRESVACLDRQ 228


>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score = 88.2 bits (217), Expect = 6e-18
 Identities = 65/224 (29%), Positives = 104/224 (46%), Gaps = 25/224 (11%)

Query: 9   ELEDWLQCPICLEVFKESLMLQCGHSYCKGCL-VSLSYHLDTKVR--------CPMCWQV 59
           +L++   C ICL+ F + +M  CGH++C+ C+ +S       K R        CP C ++
Sbjct: 9   KLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREM 68

Query: 60  VDGSSSLPNVSLAWVIE-ALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQ 118
               + LPN  L  V E A + PG  +  +C  H  PL LFC+KDQ  IC +C     H+
Sbjct: 69  SPQRNLLPNRLLTKVAEMAQQHPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHR 128

Query: 119 HHPVTPVSTVCS----RMKEELAALFSEL-------KQEQKKVDELIAKLVKNRTRIVNE 167
            H V P          +++E++  L  ++        +E++ + E   K+ + R RIV E
Sbjct: 129 LHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLE 188

Query: 168 SDVFSWVIRREFQELRHPVDEEKARCLEGIGGHTRGLVASLDMQ 211
            +  +  +  E Q L   ++ E+    E      R  VA LD Q
Sbjct: 189 FEKMNLYLVEEEQRLLQALETEE----EETASRLRESVACLDRQ 228


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score = 88.2 bits (217), Expect = 6e-18
 Identities = 57/199 (28%), Positives = 94/199 (47%), Gaps = 14/199 (7%)

Query: 10  LEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVVDGSSSLPNV 69
           L++   C ICL+ F + +M  CGH++C+ C+       +    CP C ++    +  PN 
Sbjct: 10  LQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQRNLRPNR 69

Query: 70  SLAWVIEALRL--PGDPEPK-VCVHHRNPLSLFCEKDQELICGLCGLLGSHQHHPVTPVS 126
            LA + E  R   P  P P+ VC  HR PL+ FC  +  L+C  C   G H  H V P+ 
Sbjct: 70  PLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERSGEHWAHRVRPLQ 129

Query: 127 TVCSRMKEELAALFSELKQE-------QKKVDE---LIAKLVKN-RTRIVNESDVFSWVI 175
                +K +L      L+++       Q + DE   L  K+V++ R  ++ E +    ++
Sbjct: 130 DAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGEFERLRRLL 189

Query: 176 RREFQELRHPVDEEKARCL 194
             E Q+L   ++EE+   L
Sbjct: 190 AEEEQQLLQRLEEEELEVL 208


>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score = 87.8 bits (216), Expect = 8e-18
 Identities = 67/270 (24%), Positives = 112/270 (41%), Gaps = 28/270 (10%)

Query: 9   ELEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSL-------SYHLDTK-----VRCPMC 56
           EL+    C ICLE+F+E + ++CGHS+C+ C+          S    T+     + CP C
Sbjct: 22  ELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQC 81

Query: 57  WQVVDGSSSLPNVSLAWVIEALR-------LPGDPEPKV---------CVHHRNPLSLFC 100
            +    S   PN  LA V   LR        PG+   +          C  H  P  L+C
Sbjct: 82  REPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYC 141

Query: 101 EKDQELICGLCGLLGSHQHHPVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKN 160
           + D   IC +C     H+ H V P+       KE L +    LK+E +  +   +   K 
Sbjct: 142 QDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKE 201

Query: 161 RTRIVNESDVFSWVIRREFQELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRE 220
              ++ +       +  EFQ LR  + E++ R L  +   +R +    +  L Q      
Sbjct: 202 SKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEIT 261

Query: 221 RLAQAECVLEQFGNEDHHEFIWKFHSMASR 250
           +L++    +++   +   +F+ +F S  SR
Sbjct: 262 QLSKLSSQIQETAQKPDLDFLQEFKSTLSR 291


>gi|55953112 ret finger protein 2 isoform 2 [Homo sapiens]
          Length = 410

 Score = 87.0 bits (214), Expect = 1e-17
 Identities = 60/240 (25%), Positives = 109/240 (45%), Gaps = 21/240 (8%)

Query: 10  LEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSL-------SYHLDTKVRCPMCWQVVD- 61
           LE+ L CPIC  +F +  +L C H++CK CL  +       S       +CP C +    
Sbjct: 7   LEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKETSA 66

Query: 62  -GSSSLP-NVSLAWVIEAL-RLPGDPEPKVCVHHRN-PLSLFCEKDQELICGLCGLLGSH 117
            G +SL  N SL  ++E   ++   P+  VC  H   PL++FC  D +LICG+C   G H
Sbjct: 67  TGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATRGEH 126

Query: 118 QHHPVTPVSTVCSRMKEELAALFSELKQEQK-----KVDELIAKLVKNRTRIVNESDVFS 172
             H    +    ++ ++   +LF   +  ++     ++D L     K+   +  +SD   
Sbjct: 127 TKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSD--- 183

Query: 173 WVIRREFQELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQF 232
             ++  F++L+H +D++K   L         ++ + D ++ +     +    A  + E F
Sbjct: 184 -KVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAF 242


>gi|47132524 ret finger protein 2 isoform 1 [Homo sapiens]
          Length = 407

 Score = 87.0 bits (214), Expect = 1e-17
 Identities = 60/240 (25%), Positives = 109/240 (45%), Gaps = 21/240 (8%)

Query: 10  LEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSL-------SYHLDTKVRCPMCWQVVD- 61
           LE+ L CPIC  +F +  +L C H++CK CL  +       S       +CP C +    
Sbjct: 4   LEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKETSA 63

Query: 62  -GSSSLP-NVSLAWVIEAL-RLPGDPEPKVCVHHRN-PLSLFCEKDQELICGLCGLLGSH 117
            G +SL  N SL  ++E   ++   P+  VC  H   PL++FC  D +LICG+C   G H
Sbjct: 64  TGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATRGEH 123

Query: 118 QHHPVTPVSTVCSRMKEELAALFSELKQEQK-----KVDELIAKLVKNRTRIVNESDVFS 172
             H    +    ++ ++   +LF   +  ++     ++D L     K+   +  +SD   
Sbjct: 124 TKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSD--- 180

Query: 173 WVIRREFQELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQF 232
             ++  F++L+H +D++K   L         ++ + D ++ +     +    A  + E F
Sbjct: 181 -KVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAF 239


>gi|16445412 ret finger protein 2 isoform 1 [Homo sapiens]
          Length = 407

 Score = 87.0 bits (214), Expect = 1e-17
 Identities = 60/240 (25%), Positives = 109/240 (45%), Gaps = 21/240 (8%)

Query: 10  LEDWLQCPICLEVFKESLMLQCGHSYCKGCLVSL-------SYHLDTKVRCPMCWQVVD- 61
           LE+ L CPIC  +F +  +L C H++CK CL  +       S       +CP C +    
Sbjct: 4   LEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKETSA 63

Query: 62  -GSSSLP-NVSLAWVIEAL-RLPGDPEPKVCVHHRN-PLSLFCEKDQELICGLCGLLGSH 117
            G +SL  N SL  ++E   ++   P+  VC  H   PL++FC  D +LICG+C   G H
Sbjct: 64  TGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATRGEH 123

Query: 118 QHHPVTPVSTVCSRMKEELAALFSELKQEQK-----KVDELIAKLVKNRTRIVNESDVFS 172
             H    +    ++ ++   +LF   +  ++     ++D L     K+   +  +SD   
Sbjct: 124 TKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSD--- 180

Query: 173 WVIRREFQELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQF 232
             ++  F++L+H +D++K   L         ++ + D ++ +     +    A  + E F
Sbjct: 181 -KVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAF 239


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,579,194
Number of Sequences: 37866
Number of extensions: 483076
Number of successful extensions: 2389
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 227
Number of HSP's successfully gapped in prelim test: 144
Number of HSP's that attempted gapping in prelim test: 1909
Number of HSP's gapped (non-prelim): 457
length of query: 250
length of database: 18,247,518
effective HSP length: 100
effective length of query: 150
effective length of database: 14,460,918
effective search space: 2169137700
effective search space used: 2169137700
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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