BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2 [Homo sapiens] (659 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2... 1320 0.0 gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1... 1315 0.0 gi|190886437 RALBP1 associated Eps domain containing 1 isoform b... 380 e-105 gi|190886435 RALBP1 associated Eps domain containing 1 isoform a... 363 e-100 gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 91 3e-18 gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 91 3e-18 gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 91 3e-18 gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 81 3e-15 gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 81 3e-15 gi|21264315 EH-domain containing 4 [Homo sapiens] 67 4e-11 gi|4503593 epidermal growth factor receptor pathway substrate 15... 67 7e-11 gi|10864047 epidermal growth factor receptor pathway substrate 1... 64 3e-10 gi|21361462 EH-domain containing 2 [Homo sapiens] 61 4e-09 gi|30240932 EH-domain containing 1 [Homo sapiens] 57 4e-08 gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 57 5e-08 gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 55 3e-07 gi|7657056 EH-domain containing 3 [Homo sapiens] 54 6e-07 gi|24497554 homeobox A13 [Homo sapiens] 51 3e-06 gi|222418647 mucin 7, secreted precursor [Homo sapiens] 50 7e-06 gi|222418649 mucin 7, secreted precursor [Homo sapiens] 50 7e-06 gi|222418645 mucin 7, secreted precursor [Homo sapiens] 50 7e-06 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 50 9e-06 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 50 9e-06 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 50 9e-06 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 50 9e-06 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 49 1e-05 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 49 2e-05 gi|163659920 pannexin 2 isoform 1 [Homo sapiens] 48 3e-05 gi|40353727 synaptopodin isoform A [Homo sapiens] 48 3e-05 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 48 3e-05 >gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2 [Homo sapiens] Length = 659 Score = 1320 bits (3416), Expect = 0.0 Identities = 659/659 (100%), Positives = 659/659 (100%) Query: 1 MEAAAAAAAAAAAAAAAGGGCGSGPPPLLLSEGEQQCYSELFARCAGAAGGGPGSGPPEA 60 MEAAAAAAAAAAAAAAAGGGCGSGPPPLLLSEGEQQCYSELFARCAGAAGGGPGSGPPEA Sbjct: 1 MEAAAAAAAAAAAAAAAGGGCGSGPPPLLLSEGEQQCYSELFARCAGAAGGGPGSGPPEA 60 Query: 61 ARVAPGTATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQ 120 ARVAPGTATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQ Sbjct: 61 ARVAPGTATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQ 120 Query: 121 SGLPVRIESIKCELPLPRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDED 180 SGLPVRIESIKCELPLPRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDED Sbjct: 121 SGLPVRIESIKCELPLPRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDED 180 Query: 181 KQETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSSS 240 KQETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSSS Sbjct: 181 KQETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSSS 240 Query: 241 GGPGTKPLRHQASLIRSFSVERELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSFI 300 GGPGTKPLRHQASLIRSFSVERELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSFI Sbjct: 241 GGPGTKPLRHQASLIRSFSVERELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSFI 300 Query: 301 SGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLP 360 SGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLP Sbjct: 301 SGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLP 360 Query: 361 PTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVPNQDVT 420 PTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVPNQDVT Sbjct: 361 PTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVPNQDVT 420 Query: 421 SDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTPP 480 SDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTPP Sbjct: 421 SDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTPP 480 Query: 481 PRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLSR 540 PRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLSR Sbjct: 481 PRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLSR 540 Query: 541 APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTV 600 APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTV Sbjct: 541 APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTV 600 Query: 601 QKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL 659 QKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL Sbjct: 601 QKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL 659 >gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1 [Homo sapiens] Length = 660 Score = 1315 bits (3404), Expect = 0.0 Identities = 659/660 (99%), Positives = 659/660 (99%), Gaps = 1/660 (0%) Query: 1 MEAAAAAAAAAAAAAAAGGGCGSGPPPLLLSEGEQQCYSELFARCAGAAGGGPGSGPPEA 60 MEAAAAAAAAAAAAAAAGGGCGSGPPPLLLSEGEQQCYSELFARCAGAAGGGPGSGPPEA Sbjct: 1 MEAAAAAAAAAAAAAAAGGGCGSGPPPLLLSEGEQQCYSELFARCAGAAGGGPGSGPPEA 60 Query: 61 ARVAPGTATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQ 120 ARVAPGTATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQ Sbjct: 61 ARVAPGTATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQ 120 Query: 121 SGLPVRIESIKCELPLPRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDED 180 SGLPVRIESIKCELPLPRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDED Sbjct: 121 SGLPVRIESIKCELPLPRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDED 180 Query: 181 KQ-ETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSS 239 KQ ETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSS Sbjct: 181 KQQETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSS 240 Query: 240 SGGPGTKPLRHQASLIRSFSVERELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSF 299 SGGPGTKPLRHQASLIRSFSVERELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSF Sbjct: 241 SGGPGTKPLRHQASLIRSFSVERELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSF 300 Query: 300 ISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGL 359 ISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGL Sbjct: 301 ISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGL 360 Query: 360 PPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVPNQDV 419 PPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVPNQDV Sbjct: 361 PPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVPNQDV 420 Query: 420 TSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTP 479 TSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTP Sbjct: 421 TSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTP 480 Query: 480 PPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLS 539 PPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLS Sbjct: 481 PPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLS 540 Query: 540 RAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPT 599 RAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPT Sbjct: 541 RAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPT 600 Query: 600 VQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL 659 VQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL Sbjct: 601 VQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL 660 >gi|190886437 RALBP1 associated Eps domain containing 1 isoform b [Homo sapiens] Length = 769 Score = 380 bits (976), Expect = e-105 Identities = 274/792 (34%), Positives = 379/792 (47%), Gaps = 186/792 (23%) Query: 28 LLLSEGEQQCYSELFARCAGAAGGGPGSGPPEAARVAPGTATAAAGPVADLFRASQLPAE 87 L LS+ EQ+ YS+LF+ C + G V +LFRA+QLP + Sbjct: 4 LTLSDAEQKYYSDLFSYCD----------------IESTKKVVVNGRVLELFRAAQLPND 47 Query: 88 TLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSGLPVRIESIKC--ELPLPRFMMSKND 145 + QI ELCGA R+GYFG +QFYIALKL+A AQSG P+R+ESI +LPLPRF+ SKN+ Sbjct: 48 VVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNE 107 Query: 146 GEIR----FGNPAELHGT----------KVQIPYLTTEKNSFKRMDDEDKQETQSPTMSP 191 E R + + +E G+ + Q+ + ++ + D QE SP +SP Sbjct: 108 QESRHAASYSSDSENQGSYSGVIPPPPGRGQVKKGSVSHDTVQPRTSADAQEPASPVVSP 167 Query: 192 LASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSSSGG--------- 242 SPP+SP +++ H ++E+ P P + + SS G Sbjct: 168 QQSPPTSPHTWRK----HSRHPSGGNSERPLAGPGPFWSPFGEAQSGSSAGDAVWSGHSP 223 Query: 243 -------------PGTKPL--RHQASL--------IRSFSVERELQDNSSYPDEPWRITE 279 P T L H AS+ + S + E++ SS D+PW+IT+ Sbjct: 224 PPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDDPWKITD 283 Query: 280 EQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEF 339 EQR+YYVNQF+++QPD + FI GS AK FFTKSKL I ELS+IWELSD D DGALTL EF Sbjct: 284 EQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEF 343 Query: 340 CAAFHLIVARKNGYPLPEGLPPTLQPEYLQAAFPKPKWD-----------CQLFDSYSES 388 CAAFHL+VARKNGY LPE LP +L P+ + D + S S S Sbjct: 344 CAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPS 403 Query: 389 LPA------------------------------NQQPRDLNRMEKTSVKDMADLPVPNQD 418 +P+ + Q +L R + L V D Sbjct: 404 MPSLNQTWPELNQSSEDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSD 463 Query: 419 VTSDDK--QALKSTINEALPKDVSEDPATPKDSNSLKAR-PRSRSYSSTSIEEAMKRGED 475 + ++K ++K + S + D + + R RS+S TS + Sbjct: 464 LLEENKINSSVKFASGNTVADGYSSSDSFTSDPEQIGSNVTRQRSHSGTSPDNTA----- 518 Query: 476 PPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQS--------- 526 PP PPPRPQ +HSR+SSLD+N+ F + ++G++ PPA+PPRP PSQ+ Sbjct: 519 PPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVAHPPAVPPRPQPSQAPGPAVHRPV 578 Query: 527 --------------------------------------EQVSEAELLPQL---------- 538 EQ EAE P++ Sbjct: 579 DADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEKASDPA 638 Query: 539 ---------SRAPSQAAESSPA--KKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASG 587 S+ + A S+PA K PP KP+RR+ + E++ + T +G Sbjct: 639 SSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPVRRRLKSEDELRPEVDEHTQKTG 698 Query: 588 PASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALE 647 AA + P++ + K KKAIQ +IR+NKE N VLARLNSELQQQLK+V +ERI+LE Sbjct: 699 -VLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERISLE 757 Query: 648 NQLEQLRPVTVL 659 QLEQLRP + L Sbjct: 758 VQLEQLRPFSHL 769 >gi|190886435 RALBP1 associated Eps domain containing 1 isoform a [Homo sapiens] Length = 795 Score = 363 bits (931), Expect = e-100 Identities = 275/813 (33%), Positives = 385/813 (47%), Gaps = 202/813 (24%) Query: 28 LLLSEGEQQCYSELFARCAGAAGGGPGSGPPEAARVAPGTATAAAGPVADLFRASQLPAE 87 L LS+ EQ+ YS+LF+ C + G V +LFRA+QLP + Sbjct: 4 LTLSDAEQKYYSDLFSYCD----------------IESTKKVVVNGRVLELFRAAQLPND 47 Query: 88 TLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSGLPVRIESIKC--ELPLPRFMMSKND 145 + QI ELCGA R+GYFG +QFYIALKL+A AQSG P+R+ESI +LPLPRF+ SKN+ Sbjct: 48 VVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNE 107 Query: 146 GEIR----FGNPAELHGT----------KVQIPYLTTEKNSFKRMDDEDKQETQSPTMSP 191 E R + + +E G+ + Q+ + ++ + D QE SP +SP Sbjct: 108 QESRHAASYSSDSENQGSYSGVIPPPPGRGQVKKGSVSHDTVQPRTSADAQEPASPVVSP 167 Query: 192 LASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSSSGG--------- 242 SPP+SP +++ H ++E+ P P + + SS G Sbjct: 168 QQSPPTSPHTWRK----HSRHPSGGNSERPLAGPGPFWSPFGEAQSGSSAGDAVWSGHSP 223 Query: 243 -------------PGTKPL--RHQASL--------IRSFSVERELQDNSSYPDEPWRITE 279 P T L H AS+ + S + E++ SS D+PW+IT+ Sbjct: 224 PPPQENWVSFADTPPTSTLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDDPWKITD 283 Query: 280 EQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEF 339 EQR+YYVNQF+++QPD + FI GS AK FFTKSKL I ELS+IWELSD D DGALTL EF Sbjct: 284 EQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEF 343 Query: 340 CAAFHLIVARKNGYPLPEGLPPTLQPEY-------------------------------- 367 CAAFHL+VARKNGY LPE LP +L P+ Sbjct: 344 CAAFHLVVARKNGYDLPEKLPESLMPKLIDLEDSADVGDQPGEVGYSGSPAEAPPSKSPS 403 Query: 368 ---LQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADL-PVPNQDVTSD- 422 L +P+ + ++++SE ++Q + + D A + PVP + S Sbjct: 404 MPSLNQTWPELNQSSEQWETFSERSSSSQTLTQFDSNIAPADPDTAIVHPVPIRMTPSKI 463 Query: 423 --DKQALKSTINE---------ALPKDVSEDPATPK-----DSNSLKARPRSRSYS---- 462 + LK T ++ P D+ E+ N++ S S++ Sbjct: 464 HMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKINSSVKFASGNTVDGYSSSDSFTSDPE 523 Query: 463 ---STSIEEAMKRGEDP----PTP-PPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPP 514 S + G P P P PPRPQ +HSR+SSLD+N+ F + ++G++ P Sbjct: 524 QIGSNVTRQRSHSGTSPDNTAPPPPPPRPQPSHSRSSSLDMNRTFTVTTGQQQAGVVAHP 583 Query: 515 PALPPRPCPSQS-----------------------------------------------E 527 PA+PPRP PSQ+ E Sbjct: 584 PAVPPRPQPSQAPGPAVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDE 643 Query: 528 QVSEAELLPQL-------------------SRAPSQAAESSPA--KKDVLYSQPPSKPIR 566 Q EAE P++ S+ + A S+PA K PP KP+R Sbjct: 644 QDDEAEKHPEVLPAEKASDPASSLRVAKTDSKTEEKTAASAPANVSKGTTPLAPPPKPVR 703 Query: 567 RKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLA 626 R+ + E++ + T +G AA + P++ + K KKAIQ +IR+NKE N VLA Sbjct: 704 RRLKSEDELRPEVDEHTQKTG-VLAAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLA 762 Query: 627 RLNSELQQQLKEVHQERIALENQLEQLRPVTVL 659 RLNSELQQQLK+V +ERI+LE QLEQLRP + L Sbjct: 763 RLNSELQQQLKDVLEERISLEVQLEQLRPFSHL 795 >gi|194294523 intersectin 2 isoform 3 [Homo sapiens] Length = 1670 Score = 90.9 bits (224), Expect = 3e-18 Identities = 97/342 (28%), Positives = 135/342 (39%), Gaps = 39/342 (11%) Query: 77 DLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSG--LPVRIESIKCEL 134 + F S LPA L +I L + G +F IA+KLI G LPV + I + Sbjct: 47 NFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQP 106 Query: 135 PLPRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDEDKQETQSPTMSPLAS 194 P+ ++S G N + IP + T + PL Sbjct: 107 PMFSPLISARFGMGSMPN--------LSIPQPLPPAAPITSLSSA----TSGTNLPPLMM 154 Query: 195 PPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSS----SGGPGTKPLRH 250 P P L +G + L Q P PY + P GSS GG G ++ Sbjct: 155 PTPLVPSVSTSSLPNGTASLI----QPLPIPYSSS---TLPHGSSYSLMMGGFGGASIQK 207 Query: 251 QASLI-----RSFSVERELQDNSSYPD-EPWRITEEQREYYVNQFRSLQPDPSSFISGSV 304 SLI S S L NS W + + R Y +F +L S ++SG Sbjct: 208 AQSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQ 267 Query: 305 AKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQ 364 A+N +S LS +L+ IW L+D D DG L EF A HL K G PLP LPP L Sbjct: 268 ARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELV 327 Query: 365 PEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSV 406 P + + DS + +LP+ Q+ ++ +K V Sbjct: 328 PPSFRGG--------KQIDSINGTLPSYQKMQEEEPQKKLPV 361 Score = 68.6 bits (166), Expect = 2e-11 Identities = 37/90 (41%), Positives = 51/90 (56%), Gaps = 1/90 (1%) Query: 275 WRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGAL 334 W IT E+R + QF +L+P +I+G A+NFF +S L P L+ IW LSD + DG + Sbjct: 16 WAITSEERTKHDRQFDNLKPS-GGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKM 74 Query: 335 TLPEFCAAFHLIVARKNGYPLPEGLPPTLQ 364 EF A LI + G LP LPP ++ Sbjct: 75 DQQEFSIAMKLIKLKLQGQQLPVVLPPIMK 104 >gi|194294521 intersectin 2 isoform 1 [Homo sapiens] Length = 1697 Score = 90.9 bits (224), Expect = 3e-18 Identities = 97/342 (28%), Positives = 135/342 (39%), Gaps = 39/342 (11%) Query: 77 DLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSG--LPVRIESIKCEL 134 + F S LPA L +I L + G +F IA+KLI G LPV + I + Sbjct: 47 NFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQP 106 Query: 135 PLPRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDEDKQETQSPTMSPLAS 194 P+ ++S G N + IP + T + PL Sbjct: 107 PMFSPLISARFGMGSMPN--------LSIPQPLPPAAPITSLSSA----TSGTNLPPLMM 154 Query: 195 PPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSS----SGGPGTKPLRH 250 P P L +G + L Q P PY + P GSS GG G ++ Sbjct: 155 PTPLVPSVSTSSLPNGTASLI----QPLPIPYSSS---TLPHGSSYSLMMGGFGGASIQK 207 Query: 251 QASLI-----RSFSVERELQDNSSYPD-EPWRITEEQREYYVNQFRSLQPDPSSFISGSV 304 SLI S S L NS W + + R Y +F +L S ++SG Sbjct: 208 AQSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQ 267 Query: 305 AKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQ 364 A+N +S LS +L+ IW L+D D DG L EF A HL K G PLP LPP L Sbjct: 268 ARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELV 327 Query: 365 PEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSV 406 P + + DS + +LP+ Q+ ++ +K V Sbjct: 328 PPSFRGG--------KQIDSINGTLPSYQKMQEEEPQKKLPV 361 Score = 68.6 bits (166), Expect = 2e-11 Identities = 37/90 (41%), Positives = 51/90 (56%), Gaps = 1/90 (1%) Query: 275 WRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGAL 334 W IT E+R + QF +L+P +I+G A+NFF +S L P L+ IW LSD + DG + Sbjct: 16 WAITSEERTKHDRQFDNLKPS-GGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKM 74 Query: 335 TLPEFCAAFHLIVARKNGYPLPEGLPPTLQ 364 EF A LI + G LP LPP ++ Sbjct: 75 DQQEFSIAMKLIKLKLQGQQLPVVLPPIMK 104 >gi|194294525 intersectin 2 isoform 2 [Homo sapiens] Length = 1249 Score = 90.9 bits (224), Expect = 3e-18 Identities = 97/342 (28%), Positives = 135/342 (39%), Gaps = 39/342 (11%) Query: 77 DLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSG--LPVRIESIKCEL 134 + F S LPA L +I L + G +F IA+KLI G LPV + I + Sbjct: 47 NFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQP 106 Query: 135 PLPRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDEDKQETQSPTMSPLAS 194 P+ ++S G N + IP + T + PL Sbjct: 107 PMFSPLISARFGMGSMPN--------LSIPQPLPPAAPITSLSSA----TSGTNLPPLMM 154 Query: 195 PPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSS----SGGPGTKPLRH 250 P P L +G + L Q P PY + P GSS GG G ++ Sbjct: 155 PTPLVPSVSTSSLPNGTASLI----QPLPIPYSSS---TLPHGSSYSLMMGGFGGASIQK 207 Query: 251 QASLI-----RSFSVERELQDNSSYPD-EPWRITEEQREYYVNQFRSLQPDPSSFISGSV 304 SLI S S L NS W + + R Y +F +L S ++SG Sbjct: 208 AQSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPTRLKYRQKFNTLDKSMSGYLSGFQ 267 Query: 305 AKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQ 364 A+N +S LS +L+ IW L+D D DG L EF A HL K G PLP LPP L Sbjct: 268 ARNALLQSNLSQTQLATIWTLADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELV 327 Query: 365 PEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSV 406 P + + DS + +LP+ Q+ ++ +K V Sbjct: 328 PPSFRGG--------KQIDSINGTLPSYQKMQEEEPQKKLPV 361 Score = 68.6 bits (166), Expect = 2e-11 Identities = 37/90 (41%), Positives = 51/90 (56%), Gaps = 1/90 (1%) Query: 275 WRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGAL 334 W IT E+R + QF +L+P +I+G A+NFF +S L P L+ IW LSD + DG + Sbjct: 16 WAITSEERTKHDRQFDNLKPS-GGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKM 74 Query: 335 TLPEFCAAFHLIVARKNGYPLPEGLPPTLQ 364 EF A LI + G LP LPP ++ Sbjct: 75 DQQEFSIAMKLIKLKLQGQQLPVVLPPIMK 104 >gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] Length = 1220 Score = 80.9 bits (198), Expect = 3e-15 Identities = 100/394 (25%), Positives = 157/394 (39%), Gaps = 29/394 (7%) Query: 275 WRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGAL 334 W IT E+R + QF SL+P S FI+G A+NFF +S L P L+ IW L+D + DG + Sbjct: 15 WAITVEERAKHDQQFHSLKPI-SGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 73 Query: 335 TLPEFCAAFHLIVARKNGYPLPEGLPPTL--QPEYLQAAFPKPKWDCQLFDSYSESLPAN 392 EF A LI + GY LP LPP + QP + +A + P Sbjct: 74 DQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVP 133 Query: 393 QQPRDLNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSL 452 + M T V + VP + + + LP PK S+ Sbjct: 134 MGSIPVVGMSPTLVSSVPTAAVPPLANGA-------PPVIQPLPAFAHPAATLPKSSSFS 186 Query: 453 KARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLP 512 ++ P S+ +T +++A + D + PP + ++S L ++F S T SG L Sbjct: 187 RSGPGSQ--LNTKLQKA--QSFDVASVPPVAEWAVPQSSRLKYRQLFN-SHDKTMSGHLT 241 Query: 513 PPPA---LPPRPCP-SQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPI--R 566 P A L P +Q + + Q + ++ + DV S P P+ Sbjct: 242 GPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPP 301 Query: 567 RKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLA 626 P + + + S + + P ++ + + +K + K N Sbjct: 302 EYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERG 361 Query: 627 RLNSE------LQQQLKEVHQERIALENQLEQLR 654 L E L+QQ KE QER+A + EQ R Sbjct: 362 NLELEKRRQALLEQQRKE--QERLAQLERAEQER 393 Score = 77.8 bits (190), Expect = 3e-14 Identities = 85/301 (28%), Positives = 115/301 (38%), Gaps = 43/301 (14%) Query: 77 DLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSGLPVRIESIKCELPL 136 + F S LP L QI L G +F IA+KLI ++++ + L Sbjct: 46 NFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIK-------LKLQGYQLPSAL 98 Query: 137 PRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDEDKQETQSPTMSPLASPP 196 P M K PA G +P LT +P P+ S P Sbjct: 99 PPVM--KQQPVAISSAPAFGMGGIASMPPLTAV----------------APV--PMGSIP 138 Query: 197 ---SSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSS--SGGPGTKPLRHQ 251 SP VP + + + P P A P+ SS GPG++ L + Sbjct: 139 VVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQ-LNTK 197 Query: 252 ASLIRSFSVERELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTK 311 +SF V S P W + + R Y F S S ++G A+ + Sbjct: 198 LQKAQSFDVA------SVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQ 251 Query: 312 SKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQPEYLQAA 371 S L +L+ IW LSD D DG LT EF A HLI +G P LPP L PEY+ + Sbjct: 252 SSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQP----LPPVLPPEYIPPS 307 Query: 372 F 372 F Sbjct: 308 F 308 >gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] Length = 1721 Score = 80.9 bits (198), Expect = 3e-15 Identities = 100/394 (25%), Positives = 157/394 (39%), Gaps = 29/394 (7%) Query: 275 WRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGAL 334 W IT E+R + QF SL+P S FI+G A+NFF +S L P L+ IW L+D + DG + Sbjct: 15 WAITVEERAKHDQQFHSLKPI-SGFITGDQARNFFFQSGLPQPVLAQIWALADMNNDGRM 73 Query: 335 TLPEFCAAFHLIVARKNGYPLPEGLPPTL--QPEYLQAAFPKPKWDCQLFDSYSESLPAN 392 EF A LI + GY LP LPP + QP + +A + P Sbjct: 74 DQVEFSIAMKLIKLKLQGYQLPSALPPVMKQQPVAISSAPAFGMGGIASMPPLTAVAPVP 133 Query: 393 QQPRDLNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSL 452 + M T V + VP + + + LP PK S+ Sbjct: 134 MGSIPVVGMSPTLVSSVPTAAVPPLANGA-------PPVIQPLPAFAHPAATLPKSSSFS 186 Query: 453 KARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLP 512 ++ P S+ +T +++A + D + PP + ++S L ++F S T SG L Sbjct: 187 RSGPGSQ--LNTKLQKA--QSFDVASVPPVAEWAVPQSSRLKYRQLFN-SHDKTMSGHLT 241 Query: 513 PPPA---LPPRPCP-SQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPI--R 566 P A L P +Q + + Q + ++ + DV S P P+ Sbjct: 242 GPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPP 301 Query: 567 RKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLA 626 P + + + S + + P ++ + + +K + K N Sbjct: 302 EYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERG 361 Query: 627 RLNSE------LQQQLKEVHQERIALENQLEQLR 654 L E L+QQ KE QER+A + EQ R Sbjct: 362 NLELEKRRQALLEQQRKE--QERLAQLERAEQER 393 Score = 77.8 bits (190), Expect = 3e-14 Identities = 85/301 (28%), Positives = 115/301 (38%), Gaps = 43/301 (14%) Query: 77 DLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSGLPVRIESIKCELPL 136 + F S LP L QI L G +F IA+KLI ++++ + L Sbjct: 46 NFFFQSGLPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIK-------LKLQGYQLPSAL 98 Query: 137 PRFMMSKNDGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDEDKQETQSPTMSPLASPP 196 P M K PA G +P LT +P P+ S P Sbjct: 99 PPVM--KQQPVAISSAPAFGMGGIASMPPLTAV----------------APV--PMGSIP 138 Query: 197 ---SSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSS--SGGPGTKPLRHQ 251 SP VP + + + P P A P+ SS GPG++ L + Sbjct: 139 VVGMSPTLVSSVPTAAVPPLANGAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQ-LNTK 197 Query: 252 ASLIRSFSVERELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTK 311 +SF V S P W + + R Y F S S ++G A+ + Sbjct: 198 LQKAQSFDVA------SVPPVAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQ 251 Query: 312 SKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQPEYLQAA 371 S L +L+ IW LSD D DG LT EF A HLI +G P LPP L PEY+ + Sbjct: 252 SSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQP----LPPVLPPEYIPPS 307 Query: 372 F 372 F Sbjct: 308 F 308 >gi|21264315 EH-domain containing 4 [Homo sapiens] Length = 541 Score = 67.4 bits (163), Expect = 4e-11 Identities = 41/103 (39%), Positives = 53/103 (51%), Gaps = 2/103 (1%) Query: 272 DEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCD 331 +E W + ++ + Y F +L P ISG AK SKL L IW+L+D DCD Sbjct: 439 EEEWVVAKD-KPVYDELFYTLSPINGK-ISGVNAKKEMVTSKLPNSVLGKIWKLADCDCD 496 Query: 332 GALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQPEYLQAAFPK 374 G L EF A HLI + +GY LP LPP L P + + PK Sbjct: 497 GMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRKSLPK 539 >gi|4503593 epidermal growth factor receptor pathway substrate 15 isoform A [Homo sapiens] Length = 896 Score = 66.6 bits (161), Expect = 7e-11 Identities = 82/366 (22%), Positives = 143/366 (39%), Gaps = 59/366 (16%) Query: 67 TATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSGLPVR 126 T A A + S LP L +I +L G +F++AL+L+A AQ+GL V Sbjct: 31 TGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALRLVACAQNGLEVS 90 Query: 127 IESIKCELPLPRFMMSKNDGEIRFGNPAELHGTKV-QIPYLTTEKNSFKRMDDEDKQETQ 185 + S+ +P PRF + + P + GT ++P+ + +D+ K + Sbjct: 91 LSSLNLAVPPPRFHDTSS--------PLLISGTSAAELPWAV-------KPEDKAKYDAI 135 Query: 186 SPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLV------QPEGSS 239 ++SP+ +G+ S +++ P ++ P+ + Sbjct: 136 FDSLSPV----------------NGFL----SGDKVKPVLLNSKLPVDILGRVWELSDID 175 Query: 240 SGGPGTKPLRHQASLIRSFSVERELQDNSSYPD-------EPWRITEEQREYYVNQFRSL 292 G + A + ++E+E S P + W ++ ++ Y F Sbjct: 176 HDGMLDRDEFAVAMFLVYCALEKEPVPMSLPPALVPPSKRKTWVVSPAEKAKYDEIFLKT 235 Query: 293 QPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARK-N 351 D F+SG + F K+ L L++IW L D G L+ +F AFHLI + Sbjct: 236 DKDMDGFVSGLEVREIFLKTGLPSTLLAHIWSLCDTKDCGKLSKDQFALAFHLISQKLIK 295 Query: 352 GYPLPEGLPPTLQPEYLQAAFPK------PKWDCQLFDSYSESLPANQQPRDLNRMEKTS 405 G P L P + P +A+ K P D F + E N + DL R + Sbjct: 296 GIDPPHVLTPEMIPPSDRASLQKNIIGSSPVAD---FSAIKELDTLNNEIVDLQREKNNV 352 Query: 406 VKDMAD 411 +D+ + Sbjct: 353 EQDLKE 358 Score = 39.3 bits (90), Expect = 0.012 Identities = 38/155 (24%), Positives = 55/155 (35%), Gaps = 9/155 (5%) Query: 285 YVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFH 344 Y +R + + + S A F KS L L IW+L+D D G L EF A Sbjct: 19 YEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALR 78 Query: 345 LIVARKNGYPLPEGLPPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKT 404 L+ +NG + L A P P++ A + P + +K Sbjct: 79 LVACAQNGL--------EVSLSSLNLAVPPPRFHDTSSPLLISGTSAAELPWAVKPEDKA 130 Query: 405 SVKDMADLPVPNQDVTSDDKQALKSTINEALPKDV 439 + D P S DK +N LP D+ Sbjct: 131 KYDAIFDSLSPVNGFLSGDK-VKPVLLNSKLPVDI 164 Score = 31.2 bits (69), Expect = 3.2 Identities = 51/214 (23%), Positives = 81/214 (37%), Gaps = 16/214 (7%) Query: 75 VADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQ-SGL-PVRIESIKC 132 V ++F + LP+ L I LC K G QF +A LI+ G+ P + + + Sbjct: 248 VREIFLKTGLPSTLLAHIWSLCDTKDCGKLSKDQFALAFHLISQKLIKGIDPPHVLTPEM 307 Query: 133 ELPLPRFMMSKN----DGEIRFGNPAELHGTKVQIPYLTTEKNSFKRMDDEDKQETQSPT 188 P R + KN F EL +I L EKN+ ++D +E + Sbjct: 308 IPPSDRASLQKNIIGSSPVADFSAIKELDTLNNEIVDLQREKNNV----EQDLKEKEDTI 363 Query: 189 MSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSSSGGPGTKPL 248 + QR + KL++ +Q+ E + Q E K Sbjct: 364 KQRTSEVQDLQDEVQRE--NTNLQKLQAQKQQVQELLDELDEQKAQLEEQLK--EVRKKC 419 Query: 249 RHQASLIRSFSVERELQDN--SSYPDEPWRITEE 280 +A LI S E Q++ S+Y +E + EE Sbjct: 420 AEEAQLISSLKAELTSQESQISTYEEELAKAREE 453 Score = 30.4 bits (67), Expect = 5.4 Identities = 29/130 (22%), Positives = 49/130 (37%), Gaps = 20/130 (15%) Query: 511 LPPPPALPPRPCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFR 570 LPP P RPCP LP R+ ++ P K + + P ++ Sbjct: 771 LPPKIGTPTRPCP-----------LPPGKRSINKLDSPDPFKLNDPFQPFPGNDSPKEKD 819 Query: 571 PE---NQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLAR 627 PE + T + + P++ A +P+ + K+ +E LAR Sbjct: 820 PEIFCDPFTSATTTTNKEADPSNFANFSAYPSEEDMIEWAKR------ESEREEEQRLAR 873 Query: 628 LNSELQQQLK 637 LN + Q+ L+ Sbjct: 874 LNQQEQEDLE 883 >gi|10864047 epidermal growth factor receptor pathway substrate 15-like 1 [Homo sapiens] Length = 864 Score = 64.3 bits (155), Expect = 3e-10 Identities = 47/156 (30%), Positives = 65/156 (41%), Gaps = 13/156 (8%) Query: 275 WRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGAL 334 W + E++ + F SL P + +SG K SKL + L +W+LSD D DG L Sbjct: 121 WAVRVEEKAKFDGIFESLLPI-NGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHL 179 Query: 335 TLPEFCAAFHLIVARKNGYPLPEGLPPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQ 394 EF A HL+ P+P LPP+L P K +F LPA+ Sbjct: 180 DRDEFAVAMHLVYRALEKEPVPSALPPSL--------IPPSKRKKTVFPGAVPVLPASPP 231 Query: 395 PRDLNRMEKTSVKDMADLPVPNQDVTSDDKQALKST 430 P+D R S + N + K +LK T Sbjct: 232 PKDSLR----STPSHGSVSSLNSTGSLSPKHSLKQT 263 Score = 42.0 bits (97), Expect = 0.002 Identities = 23/73 (31%), Positives = 36/73 (49%) Query: 67 TATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSGLPVR 126 T A A + S L L +I +L + G+ FY+AL+L+A AQSG V Sbjct: 31 TGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVALRLVACAQSGHEVT 90 Query: 127 IESIKCELPLPRF 139 + ++ +P P+F Sbjct: 91 LSNLNLSMPPPKF 103 Score = 39.3 bits (90), Expect = 0.012 Identities = 66/279 (23%), Positives = 104/279 (37%), Gaps = 52/279 (18%) Query: 285 YVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFH 344 Y + ++ + P + + S A F KS LS L IW+L+D + G L F A Sbjct: 19 YESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVALR 78 Query: 345 LIVARKNGYPLPEGLPPTLQPEYLQAAFPKPKWDCQLFDSYSESL----PANQQPRDLNR 400 L+ ++G+ + TL L + P PK F S L P+ + + Sbjct: 79 LVACAQSGHEV------TL--SNLNLSMPPPK-----FHDTSSPLMVTPPSAEAHWAVRV 125 Query: 401 MEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALP----------KDVSEDPATPKDSN 450 EK + + +P + S DK +N LP D+ +D +D Sbjct: 126 EEKAKFDGIFESLLPINGLLSGDK-VKPVLMNSKLPLDVLGRVWDLSDIDKDGHLDRDEF 184 Query: 451 SLKARPRSRSYSSTSIEEAMKRGEDPPT--PPPRPQKTHSRASSLDLNKVFQPSVPATKS 508 ++ R+ + A+ PP+ PP + +KT VF +VP + Sbjct: 185 AVAMHLVYRALEKEPVPSAL-----PPSLIPPSKRKKT-----------VFPGAVPVLPA 228 Query: 509 GLLPPPPALPPRPCPSQ---SEQVSEAELLPQLSRAPSQ 544 PPP R PS S S L P+ S +Q Sbjct: 229 S---PPPKDSLRSTPSHGSVSSLNSTGSLSPKHSLKQTQ 264 Score = 38.9 bits (89), Expect = 0.015 Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 1/96 (1%) Query: 271 PDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADC 330 P W + + + F D ++SG K F S L+ L++IW L+D Sbjct: 265 PTVNWVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQ 324 Query: 331 DGALTLPEFCAAFHLIVAR-KNGYPLPEGLPPTLQP 365 G L+ +F A + I + G P+ L P + P Sbjct: 325 TGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVP 360 >gi|21361462 EH-domain containing 2 [Homo sapiens] Length = 543 Score = 60.8 bits (146), Expect = 4e-09 Identities = 53/176 (30%), Positives = 81/176 (46%), Gaps = 16/176 (9%) Query: 203 QRVPLSHGYSKLRS-------SAEQMHPAPYEARQPLVQPEGSSSGGPGTKPLRHQASLI 255 Q + ++H ++K S + ++M PL++ E S G + + + + Sbjct: 360 QELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESTEVGVQGGAFEGTHM 419 Query: 256 RSFSVER------ELQDNSSYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFF 309 F VER E + S + W +T+++ +Y F +L P +SGS AK + Sbjct: 420 GPF-VERGPDEAMEDGEEGSDDEAEWVVTKDKSKYD-EIFYNLAPADGK-LSGSKAKTWM 476 Query: 310 TKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQP 365 +KL L IW+LSD D DG L EF A HLI A+ G+ LP LP L P Sbjct: 477 VGTKLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVP 532 >gi|30240932 EH-domain containing 1 [Homo sapiens] Length = 534 Score = 57.4 bits (137), Expect = 4e-08 Identities = 37/94 (39%), Positives = 48/94 (51%), Gaps = 2/94 (2%) Query: 272 DEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCD 331 D W + + + Y F +L P + I+G+ AK KSKL L IW+L+D D D Sbjct: 436 DVEW-VVGKDKPTYDEIFYTLSP-VNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDKD 493 Query: 332 GALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQP 365 G L EF A HLI + G+ LP LPP L P Sbjct: 494 GLLDDEEFALANHLIKVKLEGHELPADLPPHLVP 527 >gi|116256464 hypothetical protein LOC343990 [Homo sapiens] Length = 962 Score = 57.0 bits (136), Expect = 5e-08 Identities = 59/246 (23%), Positives = 97/246 (39%), Gaps = 27/246 (10%) Query: 390 PANQQPRDLNRME-KTSVKDMADLPVPNQDVTSDDKQALKSTINE---ALPKDVSED--- 442 P NQ+ + R+ + + ++DL ++ +++K L+ + E + +DV+ D Sbjct: 232 PRNQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGP 291 Query: 443 ----PAT---PKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDL 495 PA P + + +AR + S + S+EE GEDP + P P+ Sbjct: 292 EPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPE----------- 340 Query: 496 NKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDV 555 + +P T P PP PP P P +Q EA + A +A E A +DV Sbjct: 341 --LAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDV 398 Query: 556 LYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAI 615 P + P PE E +A GP + + PT ++K A Sbjct: 399 ASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAP 458 Query: 616 RKNKEA 621 +EA Sbjct: 459 EPEREA 464 >gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax homolog 2 [Homo sapiens] Length = 1210 Score = 54.7 bits (130), Expect = 3e-07 Identities = 110/511 (21%), Positives = 177/511 (34%), Gaps = 110/511 (21%) Query: 178 DEDKQETQSPTMS-PLASPPSSPPH--YQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQ 234 D + SP +S P PP SP H Q +P + G SK+ Sbjct: 191 DSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVH------------------- 231 Query: 235 PEGSSSGGPGTKPLRHQASLIRSFSVERELQDNSSYPDEPWRIT-------------EEQ 281 GSS+ G P + L + QD+ P +P T +++ Sbjct: 232 --GSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQK 289 Query: 282 REYYVNQFRSLQPDPSSF-----ISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTL 336 YV PS + + F K+ L +P + + +L T Sbjct: 290 PTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTY 349 Query: 337 P-EFCAAFHLIVARKNGYPLPEGL---PPTLQPEYLQAAFPKPKWDCQLFDSYSESLPAN 392 E ++ + +P P P T +P + FP P D Q + S+ N Sbjct: 350 SNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEP----SKFPFPTKDSQ----HVSSVTQN 401 Query: 393 QQPRDL------NRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSE---DP 443 Q+ D N + TS DL + + + SD +Q + + + P + +P Sbjct: 402 QKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSE-DSDSEQTPEKPPSSSAPPSAPQSLPEP 460 Query: 444 ATPKDSNSLKARPRSRSYSSTSIEEAMKRGE-------DPPTPPPRPQKTHSRASSLDLN 496 S+S ++ S S SS+ E + + P P P P T+ L Sbjct: 461 VASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLT 520 Query: 497 KVFQPSVPATKSGLLPPPPALPPRPCPSQ---SEQVSEAELLPQLS-----RAPSQA--- 545 KV QP+ P PP P S S++ SE++ P S RAP +A Sbjct: 521 KVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHP 580 Query: 546 ---------AESSPAKKDVLYSQPPSKPIRRKFRPENQA------------------TEN 578 A+ P ++ + ++ P KP++ R ++ T Sbjct: 581 GKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSK 640 Query: 579 QEPSTAASG-PASAATMKPHPTVQKQSSKQK 608 +P G P +AA+ +P P V S K+K Sbjct: 641 DKPKVKTKGRPRAAASNEPKPAVPPSSEKKK 671 Score = 35.4 bits (80), Expect = 0.17 Identities = 50/244 (20%), Positives = 94/244 (38%), Gaps = 44/244 (18%) Query: 434 ALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPP-TPPPRPQKTHSRASS 492 +LP V P +P SN + PR++ S +G P +P K H + + Sbjct: 203 SLPSPVP--PLSPIHSNQ-QTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETP 259 Query: 493 LDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLSRAPSQAAE----- 547 D + P+ P +++ PPP+LP + Q + + + +APS++ E Sbjct: 260 QD--SLVAPAQPPSQTF---PPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLP 314 Query: 548 -------------SSPAKKDVLYSQPPSKPIRRKFRPENQATEN---------QEPSTAA 585 PAK + + PS+ + + + E E P TA Sbjct: 315 EDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAI 374 Query: 586 SGPASAATMK-PHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERI 644 P++A K P PT Q +++ +N++ ++ +S QQ + ++ + Sbjct: 375 HTPSTAEPSKFPFPTKDSQH-------VSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDL 427 Query: 645 ALEN 648 L + Sbjct: 428 QLSD 431 Score = 35.4 bits (80), Expect = 0.17 Identities = 52/251 (20%), Positives = 93/251 (37%), Gaps = 30/251 (11%) Query: 363 LQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVP----NQD 418 +Q + + P P D +L P P + M K ++ ++ +P P ++ Sbjct: 730 VQEDSRKDRLPLPLRDTKLLS------PLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQ 783 Query: 419 VTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPT 478 ++DKQ A K SE ++ DS+S A+ R + ++ ++ + Sbjct: 784 RKAEDKQP------PAGKKHSSEKRSS--DSSSKLAKKRKGEAERDCDNKKIRLEKEIKS 835 Query: 479 PPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQL 538 +H +S K +PS ++K +LPPPP S S Q L + Sbjct: 836 QSSSSSSSHKESSK---TKPSRPSSQSSKKEMLPPPPV-------SSSSQKPAKPALKRS 885 Query: 539 SRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHP 598 R + P S I ++ R E + + + +SG A P P Sbjct: 886 RREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSG--DTANPFPVP 943 Query: 599 TVQKQSSKQKK 609 ++ +SK K Sbjct: 944 SLPNGNSKPGK 954 Score = 32.7 bits (73), Expect = 1.1 Identities = 100/483 (20%), Positives = 172/483 (35%), Gaps = 60/483 (12%) Query: 177 DDEDKQETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPE 236 D ED Q+P P +S P S P P++ +S SSAE + ++ + E Sbjct: 431 DSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHS---SSAESESTSDSDSSSD-SESE 486 Query: 237 GSSSGGPGTKPLRHQASLIRSFSVERELQDN-------SSYPDEPWRITEEQREYYVNQF 289 SSS +PL A + + DN + P E R TE R + ++ Sbjct: 487 SSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKG 546 Query: 290 RSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVAR 349 S D ++ S +K+ KS P +A G + + A + Sbjct: 547 SS---DSATSQEHSESKDPPPKSSSKAPRAP-----PEAPHPGKRSCQKSPAQQEPPQRQ 598 Query: 350 KNGYPLPE---------GLPPTLQPEYLQAAFPKPKWDCQLFDS---YSESLP---ANQQ 394 G P+ G +LQ E P D D ++ P A+ + Sbjct: 599 TVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNE 658 Query: 395 PRDLNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKA 454 P+ K + LP P++ ++ + K + + P+ + P T + Sbjct: 659 PKPAVPPSSEKKKHKSSLPAPSKALSG--PEPAKDNVEDRTPEHFALVPLTES-----QG 711 Query: 455 RPRSRSYSSTS-------IEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATK 507 P S S S TS ++E ++ P P R K S + + Sbjct: 712 PPHSGSGSRTSGCRQAVVVQEDSRKDRLP--LPLRDTKLLSPLRDTPPPQSLMVKITLDL 769 Query: 508 SGLLPPPPALPPRPCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRR 567 +P PP R ++ +Q + R+ +++ + +K +K IR Sbjct: 770 LSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRL 829 Query: 568 KFRPENQATEN-----QEPSTAASGPASAATMK---PHPTVQKQSSKQKKAIQTAIRKNK 619 + ++Q++ + + T S P+S ++ K P P V SS QK A R + Sbjct: 830 EKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPV--SSSSQKPAKPALKRSRR 887 Query: 620 EAN 622 EA+ Sbjct: 888 EAD 890 >gi|7657056 EH-domain containing 3 [Homo sapiens] Length = 535 Score = 53.5 bits (127), Expect = 6e-07 Identities = 35/94 (37%), Positives = 46/94 (48%), Gaps = 2/94 (2%) Query: 272 DEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCD 331 D W + + + Y F +L P I+G+ AK +SKL L IW+L+D D D Sbjct: 436 DAEWVVARD-KPMYDEIFYTLSPVDGK-ITGANAKKEMVRSKLPNSVLGKIWKLADIDKD 493 Query: 332 GALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQP 365 G L EF A HLI + G+ LP LP L P Sbjct: 494 GMLDDDEFALANHLIKVKLEGHELPNELPAHLLP 527 >gi|24497554 homeobox A13 [Homo sapiens] Length = 388 Score = 51.2 bits (121), Expect = 3e-06 Identities = 39/98 (39%), Positives = 41/98 (41%), Gaps = 22/98 (22%) Query: 1 MEAAAAAAAAAAAAAAAGGGCGSGPPPLLLSEG----------------EQQCY------ 38 ME AAAAAAAAAAAAAAG G G P P + G QC Sbjct: 35 MEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHP 94 Query: 39 SELFARCAGAAGGGPGSGPPEAARVAPGTATAAAGPVA 76 + L A A PG PP AA A A AAA A Sbjct: 95 APLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAAAAAA 132 Score = 41.2 bits (95), Expect = 0.003 Identities = 39/104 (37%), Positives = 47/104 (45%), Gaps = 25/104 (24%) Query: 3 AAAAAAAAAAAAAAAGGGCGSGPPPLLLSEGEQQCYSELFARCAGAA--GGGP------- 53 AAAAAAAAAAAAAAA G GP +E +QC + C+ AA GP Sbjct: 119 AAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQC-----SPCSAAAQSSSGPAALPYGY 173 Query: 54 -GSGPPEAARVAP----------GTATAAAGPVADLFRASQLPA 86 GSG AR+ P + AAA AD + + PA Sbjct: 174 FGSGYYPCARMGPHPNAIKSCAQPASAAAAAAFADKYMDTAGPA 217 >gi|222418647 mucin 7, secreted precursor [Homo sapiens] Length = 377 Score = 50.1 bits (118), Expect = 7e-06 Identities = 44/200 (22%), Positives = 75/200 (37%), Gaps = 26/200 (13%) Query: 417 QDVTSDDKQALKSTINEALPKDVSEDPATPK-------------DSNSLKARPRSRSYSS 463 ++V + A + +N P+D + P TP ++ + P + + + Sbjct: 143 ENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAP 202 Query: 464 TSIEEAMKRGEDPPTPP---PRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPP-ALPP 519 S + PPTPP P P + + + + PA S PP A+PP Sbjct: 203 PSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPP 262 Query: 520 RPCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQ 579 P + + S A P+ + AP + ++PA PPS P ++ T N Sbjct: 263 TPSATTLDP-SSASAPPETTAAPPTPSATTPA--------PPSSPAPQETTAAPITTPNS 313 Query: 580 EPSTAASGPASAATMKPHPT 599 P+T A + + H T Sbjct: 314 SPTTLAPDTSETSAAPTHQT 333 >gi|222418649 mucin 7, secreted precursor [Homo sapiens] Length = 377 Score = 50.1 bits (118), Expect = 7e-06 Identities = 44/200 (22%), Positives = 75/200 (37%), Gaps = 26/200 (13%) Query: 417 QDVTSDDKQALKSTINEALPKDVSEDPATPK-------------DSNSLKARPRSRSYSS 463 ++V + A + +N P+D + P TP ++ + P + + + Sbjct: 143 ENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAP 202 Query: 464 TSIEEAMKRGEDPPTPP---PRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPP-ALPP 519 S + PPTPP P P + + + + PA S PP A+PP Sbjct: 203 PSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPP 262 Query: 520 RPCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQ 579 P + + S A P+ + AP + ++PA PPS P ++ T N Sbjct: 263 TPSATTLDP-SSASAPPETTAAPPTPSATTPA--------PPSSPAPQETTAAPITTPNS 313 Query: 580 EPSTAASGPASAATMKPHPT 599 P+T A + + H T Sbjct: 314 SPTTLAPDTSETSAAPTHQT 333 >gi|222418645 mucin 7, secreted precursor [Homo sapiens] Length = 377 Score = 50.1 bits (118), Expect = 7e-06 Identities = 44/200 (22%), Positives = 75/200 (37%), Gaps = 26/200 (13%) Query: 417 QDVTSDDKQALKSTINEALPKDVSEDPATPK-------------DSNSLKARPRSRSYSS 463 ++V + A + +N P+D + P TP ++ + P + + + Sbjct: 143 ENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAP 202 Query: 464 TSIEEAMKRGEDPPTPP---PRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPP-ALPP 519 S + PPTPP P P + + + + PA S PP A+PP Sbjct: 203 PSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPP 262 Query: 520 RPCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQ 579 P + + S A P+ + AP + ++PA PPS P ++ T N Sbjct: 263 TPSATTLDP-SSASAPPETTAAPPTPSATTPA--------PPSSPAPQETTAAPITTPNS 313 Query: 580 EPSTAASGPASAATMKPHPT 599 P+T A + + H T Sbjct: 314 SPTTLAPDTSETSAAPTHQT 333 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 49.7 bits (117), Expect = 9e-06 Identities = 58/272 (21%), Positives = 89/272 (32%), Gaps = 54/272 (19%) Query: 396 RDLNRMEKTSVKDMAD--------------------LPVPNQDVTSDDKQALKSTINEAL 435 ++ +EKTS KD+A L P + + K+ +T E Sbjct: 174 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 233 Query: 436 PKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDP-PTPP--PRPQKTHSRASS 492 P + P TPK+ A ++S +T E A ++P PT P P P T A + Sbjct: 234 PTTIKSAPTTPKEP----APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 289 Query: 493 LDLNKVFQPSVPATKSGLLPPP---------------PALPPRPCPSQSEQV--SEAELL 535 + P PA + P P P P P P+ E + E Sbjct: 290 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 349 Query: 536 PQLSRAPSQAAESSPAKKDVLYSQP----------PSKPIRRKFRPENQATENQEPSTAA 585 P + P+ PA P P +P + T+ P+T Sbjct: 350 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 409 Query: 586 SGPASAATMKPHPTVQKQSSKQKKAIQTAIRK 617 S P + P T + + K+ T +K Sbjct: 410 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK 441 Score = 48.5 bits (114), Expect = 2e-05 Identities = 57/255 (22%), Positives = 90/255 (35%), Gaps = 21/255 (8%) Query: 360 PPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADL------P 413 P P +++A PK + + P P T+ K+ A P Sbjct: 229 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 288 Query: 414 VPNQDVTSDDKQALKSTINEALPKDVSED-PATPKDSNSLKARPRSRSYSSTSIEEAMKR 472 + + K+ +T + P E P TPK+ + + T+ E A Sbjct: 289 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA----PTTKEPAPTT 344 Query: 473 GEDP-PTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPS--QSEQV 529 ++P PT P +P T + + K +P+ TK P P P P P+ +S Sbjct: 345 PKEPAPTAPKKPAPTTPKEPAPTTPK--EPAPTTTKE----PSPTTPKEPAPTTTKSAPT 398 Query: 530 SEAELLPQLSR-APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGP 588 + E P ++ AP+ E SP P +P + T + T P Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 458 Query: 589 ASAATMKPHPTVQKQ 603 A T KP PT K+ Sbjct: 459 APTTTKKPAPTTPKE 473 Score = 44.7 bits (104), Expect = 3e-04 Identities = 42/191 (21%), Positives = 67/191 (35%), Gaps = 21/191 (10%) Query: 415 PNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGE 474 P + + K+ +T E P P TPK+ P+ + ++ E Sbjct: 314 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP--APTAPKKPAPTTPK--------E 363 Query: 475 DPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAEL 534 PT P P T ++ S K +P+ TKS P P P ++S + E Sbjct: 364 PAPTTPKEPAPTTTKEPSPTTPK--EPAPTTTKSA---PTTTKEPAPTTTKSAPTTPKEP 418 Query: 535 LPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATM 594 P ++ P+ PA P KP + T + T PA Sbjct: 419 SPTTTKEPAPTTPKEPAPTT------PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 472 Query: 595 KPHPTVQKQSS 605 +P PT K+++ Sbjct: 473 EPAPTTPKETA 483 Score = 43.9 bits (102), Expect = 5e-04 Identities = 60/272 (22%), Positives = 88/272 (32%), Gaps = 49/272 (18%) Query: 356 PEGLPPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVP 415 PE L PT E +P + + P P T+ K+ A P Sbjct: 511 PEELAPTTPEEPTPTTPEEP----------APTTPKAAAPNTPKEPAPTTPKEPAPT-TP 559 Query: 416 NQDVTSDDKQALKSTINEALPKDVSED-PATPKDSNSLKARPRSRSYSSTSIEEAMKRGE 474 + + K+ +T P + E P TPK +P + + T+ +E Sbjct: 560 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK-------KPAPKELAPTTTKEPTSTTC 612 Query: 475 DPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLP-----PPPALPPRPCPSQSEQV 529 D P P P+ T + P T G P P P P +P P Sbjct: 613 DKPAPTT-PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK----- 666 Query: 530 SEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPS-TAASGP 588 EL P ++ P+ PA P+ P E T +EP+ T P Sbjct: 667 ---ELAPTTTKGPTSTTSDKPA---------PTTP------KETAPTTPKEPAPTTPKKP 708 Query: 589 ASAATMKPHPTVQKQSSKQKKAIQTAIRKNKE 620 A P PT + S+ T I K+ + Sbjct: 709 APTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 740 Score = 43.1 bits (100), Expect = 8e-04 Identities = 41/186 (22%), Positives = 65/186 (34%), Gaps = 16/186 (8%) Query: 415 PNQDVTSDDKQALKSTINEALPKDVSE-DPATPKDSNSLKARPRSRSYSSTSIEEAMKRG 473 P + + K+ +T E P E P TPK+ A ++S +T+ E A Sbjct: 353 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP----APTTTKSAPTTTKEPAPTTT 408 Query: 474 EDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAE 533 + PT P P T ++ + K P+ P P P P P P+ ++ + Sbjct: 409 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK------PAPTTPKEPAPTTPKEPA--- 459 Query: 534 LLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAAT 593 P ++ P+ PA + P + PE A E + A T Sbjct: 460 --PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 517 Query: 594 MKPHPT 599 PT Sbjct: 518 TPEEPT 523 Score = 42.4 bits (98), Expect = 0.001 Identities = 42/197 (21%), Positives = 73/197 (37%), Gaps = 12/197 (6%) Query: 413 PVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKR 472 P P+ SD + T+N+ + E T K +++ + + + SIE+ + Sbjct: 126 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 185 Query: 473 GEDPPT-----PPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSE 527 P + P P+ + T ++ +L K P+ P + P P P +S Sbjct: 186 DLAPTSKVLAKPTPKAETT-TKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIKSA 240 Query: 528 QVSEAELLPQLSR-APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAAS 586 + E P ++ AP+ E +P P +P + T P+T Sbjct: 241 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 300 Query: 587 GPASAATMKPHPTVQKQ 603 PA KP PT K+ Sbjct: 301 -PAPTTPKKPAPTTPKE 316 Score = 39.7 bits (91), Expect = 0.009 Identities = 45/232 (19%), Positives = 73/232 (31%), Gaps = 25/232 (10%) Query: 390 PANQQPRDLNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDS 449 P P T+ K + T+ +K A T E L E+P Sbjct: 471 PKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA--PTTPEELAPTTPEEPTPTTPE 528 Query: 450 NSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSG 509 P++ + ++ E PT P P T + ++ K P+ Sbjct: 529 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT------ 582 Query: 510 LLPPPPALPPRPCPSQSEQVSEAE----------------LLPQLSRAPSQAAESSPAKK 553 L P P P +P P + + E P + P+ PA Sbjct: 583 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 642 Query: 554 DVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSS 605 + P + P+ A + P+T GP S + KP PT K+++ Sbjct: 643 TPKGTAPTTLKEPAPTTPKKPAPKELAPTT-TKGPTSTTSDKPAPTTPKETA 693 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 49.7 bits (117), Expect = 9e-06 Identities = 58/272 (21%), Positives = 89/272 (32%), Gaps = 54/272 (19%) Query: 396 RDLNRMEKTSVKDMAD--------------------LPVPNQDVTSDDKQALKSTINEAL 435 ++ +EKTS KD+A L P + + K+ +T E Sbjct: 215 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 274 Query: 436 PKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDP-PTPP--PRPQKTHSRASS 492 P + P TPK+ A ++S +T E A ++P PT P P P T A + Sbjct: 275 PTTIKSAPTTPKEP----APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 330 Query: 493 LDLNKVFQPSVPATKSGLLPPP---------------PALPPRPCPSQSEQV--SEAELL 535 + P PA + P P P P P P+ E + E Sbjct: 331 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 390 Query: 536 PQLSRAPSQAAESSPAKKDVLYSQP----------PSKPIRRKFRPENQATENQEPSTAA 585 P + P+ PA P P +P + T+ P+T Sbjct: 391 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 450 Query: 586 SGPASAATMKPHPTVQKQSSKQKKAIQTAIRK 617 S P + P T + + K+ T +K Sbjct: 451 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK 482 Score = 48.5 bits (114), Expect = 2e-05 Identities = 57/255 (22%), Positives = 90/255 (35%), Gaps = 21/255 (8%) Query: 360 PPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADL------P 413 P P +++A PK + + P P T+ K+ A P Sbjct: 270 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 329 Query: 414 VPNQDVTSDDKQALKSTINEALPKDVSED-PATPKDSNSLKARPRSRSYSSTSIEEAMKR 472 + + K+ +T + P E P TPK+ + + T+ E A Sbjct: 330 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA----PTTKEPAPTT 385 Query: 473 GEDP-PTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPS--QSEQV 529 ++P PT P +P T + + K +P+ TK P P P P P+ +S Sbjct: 386 PKEPAPTAPKKPAPTTPKEPAPTTPK--EPAPTTTKE----PSPTTPKEPAPTTTKSAPT 439 Query: 530 SEAELLPQLSR-APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGP 588 + E P ++ AP+ E SP P +P + T + T P Sbjct: 440 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 499 Query: 589 ASAATMKPHPTVQKQ 603 A T KP PT K+ Sbjct: 500 APTTTKKPAPTTPKE 514 Score = 44.7 bits (104), Expect = 3e-04 Identities = 42/191 (21%), Positives = 67/191 (35%), Gaps = 21/191 (10%) Query: 415 PNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGE 474 P + + K+ +T E P P TPK+ P+ + ++ E Sbjct: 355 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP--APTAPKKPAPTTPK--------E 404 Query: 475 DPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAEL 534 PT P P T ++ S K +P+ TKS P P P ++S + E Sbjct: 405 PAPTTPKEPAPTTTKEPSPTTPK--EPAPTTTKSA---PTTTKEPAPTTTKSAPTTPKEP 459 Query: 535 LPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATM 594 P ++ P+ PA P KP + T + T PA Sbjct: 460 SPTTTKEPAPTTPKEPAPTT------PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 513 Query: 595 KPHPTVQKQSS 605 +P PT K+++ Sbjct: 514 EPAPTTPKETA 524 Score = 43.9 bits (102), Expect = 5e-04 Identities = 60/272 (22%), Positives = 88/272 (32%), Gaps = 49/272 (18%) Query: 356 PEGLPPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVP 415 PE L PT E +P + + P P T+ K+ A P Sbjct: 552 PEELAPTTPEEPTPTTPEEP----------APTTPKAAAPNTPKEPAPTTPKEPAPT-TP 600 Query: 416 NQDVTSDDKQALKSTINEALPKDVSED-PATPKDSNSLKARPRSRSYSSTSIEEAMKRGE 474 + + K+ +T P + E P TPK +P + + T+ +E Sbjct: 601 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK-------KPAPKELAPTTTKEPTSTTC 653 Query: 475 DPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLP-----PPPALPPRPCPSQSEQV 529 D P P P+ T + P T G P P P P +P P Sbjct: 654 DKPAPTT-PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK----- 707 Query: 530 SEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPS-TAASGP 588 EL P ++ P+ PA P+ P E T +EP+ T P Sbjct: 708 ---ELAPTTTKGPTSTTSDKPA---------PTTP------KETAPTTPKEPAPTTPKKP 749 Query: 589 ASAATMKPHPTVQKQSSKQKKAIQTAIRKNKE 620 A P PT + S+ T I K+ + Sbjct: 750 APTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 781 Score = 43.1 bits (100), Expect = 8e-04 Identities = 41/186 (22%), Positives = 65/186 (34%), Gaps = 16/186 (8%) Query: 415 PNQDVTSDDKQALKSTINEALPKDVSE-DPATPKDSNSLKARPRSRSYSSTSIEEAMKRG 473 P + + K+ +T E P E P TPK+ A ++S +T+ E A Sbjct: 394 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP----APTTTKSAPTTTKEPAPTTT 449 Query: 474 EDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAE 533 + PT P P T ++ + K P+ P P P P P P+ ++ + Sbjct: 450 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK------PAPTTPKEPAPTTPKEPA--- 500 Query: 534 LLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAAT 593 P ++ P+ PA + P + PE A E + A T Sbjct: 501 --PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 558 Query: 594 MKPHPT 599 PT Sbjct: 559 TPEEPT 564 Score = 42.4 bits (98), Expect = 0.001 Identities = 42/197 (21%), Positives = 73/197 (37%), Gaps = 12/197 (6%) Query: 413 PVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKR 472 P P+ SD + T+N+ + E T K +++ + + + SIE+ + Sbjct: 167 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 226 Query: 473 GEDPPT-----PPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSE 527 P + P P+ + T ++ +L K P+ P + P P P +S Sbjct: 227 DLAPTSKVLAKPTPKAETT-TKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIKSA 281 Query: 528 QVSEAELLPQLSR-APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAAS 586 + E P ++ AP+ E +P P +P + T P+T Sbjct: 282 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 341 Query: 587 GPASAATMKPHPTVQKQ 603 PA KP PT K+ Sbjct: 342 -PAPTTPKKPAPTTPKE 357 Score = 39.7 bits (91), Expect = 0.009 Identities = 45/232 (19%), Positives = 73/232 (31%), Gaps = 25/232 (10%) Query: 390 PANQQPRDLNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDS 449 P P T+ K + T+ +K A T E L E+P Sbjct: 512 PKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA--PTTPEELAPTTPEEPTPTTPE 569 Query: 450 NSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSG 509 P++ + ++ E PT P P T + ++ K P+ Sbjct: 570 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT------ 623 Query: 510 LLPPPPALPPRPCPSQSEQVSEAE----------------LLPQLSRAPSQAAESSPAKK 553 L P P P +P P + + E P + P+ PA Sbjct: 624 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 683 Query: 554 DVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSS 605 + P + P+ A + P+T GP S + KP PT K+++ Sbjct: 684 TPKGTAPTTLKEPAPTTPKKPAPKELAPTT-TKGPTSTTSDKPAPTTPKETA 734 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 49.7 bits (117), Expect = 9e-06 Identities = 58/272 (21%), Positives = 89/272 (32%), Gaps = 54/272 (19%) Query: 396 RDLNRMEKTSVKDMAD--------------------LPVPNQDVTSDDKQALKSTINEAL 435 ++ +EKTS KD+A L P + + K+ +T E Sbjct: 267 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 326 Query: 436 PKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDP-PTPP--PRPQKTHSRASS 492 P + P TPK+ A ++S +T E A ++P PT P P P T A + Sbjct: 327 PTTIKSAPTTPKEP----APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 382 Query: 493 LDLNKVFQPSVPATKSGLLPPP---------------PALPPRPCPSQSEQV--SEAELL 535 + P PA + P P P P P P+ E + E Sbjct: 383 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 442 Query: 536 PQLSRAPSQAAESSPAKKDVLYSQP----------PSKPIRRKFRPENQATENQEPSTAA 585 P + P+ PA P P +P + T+ P+T Sbjct: 443 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 502 Query: 586 SGPASAATMKPHPTVQKQSSKQKKAIQTAIRK 617 S P + P T + + K+ T +K Sbjct: 503 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK 534 Score = 48.5 bits (114), Expect = 2e-05 Identities = 57/255 (22%), Positives = 90/255 (35%), Gaps = 21/255 (8%) Query: 360 PPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADL------P 413 P P +++A PK + + P P T+ K+ A P Sbjct: 322 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 381 Query: 414 VPNQDVTSDDKQALKSTINEALPKDVSED-PATPKDSNSLKARPRSRSYSSTSIEEAMKR 472 + + K+ +T + P E P TPK+ + + T+ E A Sbjct: 382 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA----PTTKEPAPTT 437 Query: 473 GEDP-PTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPS--QSEQV 529 ++P PT P +P T + + K +P+ TK P P P P P+ +S Sbjct: 438 PKEPAPTAPKKPAPTTPKEPAPTTPK--EPAPTTTKE----PSPTTPKEPAPTTTKSAPT 491 Query: 530 SEAELLPQLSR-APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGP 588 + E P ++ AP+ E SP P +P + T + T P Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 551 Query: 589 ASAATMKPHPTVQKQ 603 A T KP PT K+ Sbjct: 552 APTTTKKPAPTTPKE 566 Score = 44.7 bits (104), Expect = 3e-04 Identities = 42/191 (21%), Positives = 67/191 (35%), Gaps = 21/191 (10%) Query: 415 PNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGE 474 P + + K+ +T E P P TPK+ P+ + ++ E Sbjct: 407 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP--APTAPKKPAPTTPK--------E 456 Query: 475 DPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAEL 534 PT P P T ++ S K +P+ TKS P P P ++S + E Sbjct: 457 PAPTTPKEPAPTTTKEPSPTTPK--EPAPTTTKSA---PTTTKEPAPTTTKSAPTTPKEP 511 Query: 535 LPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATM 594 P ++ P+ PA P KP + T + T PA Sbjct: 512 SPTTTKEPAPTTPKEPAPTT------PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 565 Query: 595 KPHPTVQKQSS 605 +P PT K+++ Sbjct: 566 EPAPTTPKETA 576 Score = 43.9 bits (102), Expect = 5e-04 Identities = 60/272 (22%), Positives = 88/272 (32%), Gaps = 49/272 (18%) Query: 356 PEGLPPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVP 415 PE L PT E +P + + P P T+ K+ A P Sbjct: 604 PEELAPTTPEEPTPTTPEEP----------APTTPKAAAPNTPKEPAPTTPKEPAPT-TP 652 Query: 416 NQDVTSDDKQALKSTINEALPKDVSED-PATPKDSNSLKARPRSRSYSSTSIEEAMKRGE 474 + + K+ +T P + E P TPK +P + + T+ +E Sbjct: 653 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK-------KPAPKELAPTTTKEPTSTTC 705 Query: 475 DPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLP-----PPPALPPRPCPSQSEQV 529 D P P P+ T + P T G P P P P +P P Sbjct: 706 DKPAPTT-PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK----- 759 Query: 530 SEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPS-TAASGP 588 EL P ++ P+ PA P+ P E T +EP+ T P Sbjct: 760 ---ELAPTTTKGPTSTTSDKPA---------PTTP------KETAPTTPKEPAPTTPKKP 801 Query: 589 ASAATMKPHPTVQKQSSKQKKAIQTAIRKNKE 620 A P PT + S+ T I K+ + Sbjct: 802 APTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 833 Score = 43.1 bits (100), Expect = 8e-04 Identities = 41/186 (22%), Positives = 65/186 (34%), Gaps = 16/186 (8%) Query: 415 PNQDVTSDDKQALKSTINEALPKDVSE-DPATPKDSNSLKARPRSRSYSSTSIEEAMKRG 473 P + + K+ +T E P E P TPK+ A ++S +T+ E A Sbjct: 446 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP----APTTTKSAPTTTKEPAPTTT 501 Query: 474 EDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAE 533 + PT P P T ++ + K P+ P P P P P P+ ++ + Sbjct: 502 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK------PAPTTPKEPAPTTPKEPA--- 552 Query: 534 LLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAAT 593 P ++ P+ PA + P + PE A E + A T Sbjct: 553 --PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 610 Query: 594 MKPHPT 599 PT Sbjct: 611 TPEEPT 616 Score = 42.4 bits (98), Expect = 0.001 Identities = 42/197 (21%), Positives = 73/197 (37%), Gaps = 12/197 (6%) Query: 413 PVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKR 472 P P+ SD + T+N+ + E T K +++ + + + SIE+ + Sbjct: 219 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 278 Query: 473 GEDPPT-----PPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSE 527 P + P P+ + T ++ +L K P+ P + P P P +S Sbjct: 279 DLAPTSKVLAKPTPKAETT-TKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIKSA 333 Query: 528 QVSEAELLPQLSR-APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAAS 586 + E P ++ AP+ E +P P +P + T P+T Sbjct: 334 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 393 Query: 587 GPASAATMKPHPTVQKQ 603 PA KP PT K+ Sbjct: 394 -PAPTTPKKPAPTTPKE 409 Score = 39.7 bits (91), Expect = 0.009 Identities = 45/232 (19%), Positives = 73/232 (31%), Gaps = 25/232 (10%) Query: 390 PANQQPRDLNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDS 449 P P T+ K + T+ +K A T E L E+P Sbjct: 564 PKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA--PTTPEELAPTTPEEPTPTTPE 621 Query: 450 NSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSG 509 P++ + ++ E PT P P T + ++ K P+ Sbjct: 622 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT------ 675 Query: 510 LLPPPPALPPRPCPSQSEQVSEAE----------------LLPQLSRAPSQAAESSPAKK 553 L P P P +P P + + E P + P+ PA Sbjct: 676 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 735 Query: 554 DVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSS 605 + P + P+ A + P+T GP S + KP PT K+++ Sbjct: 736 TPKGTAPTTLKEPAPTTPKKPAPKELAPTT-TKGPTSTTSDKPAPTTPKETA 786 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 49.7 bits (117), Expect = 9e-06 Identities = 58/272 (21%), Positives = 89/272 (32%), Gaps = 54/272 (19%) Query: 396 RDLNRMEKTSVKDMAD--------------------LPVPNQDVTSDDKQALKSTINEAL 435 ++ +EKTS KD+A L P + + K+ +T E Sbjct: 308 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 367 Query: 436 PKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDP-PTPP--PRPQKTHSRASS 492 P + P TPK+ A ++S +T E A ++P PT P P P T A + Sbjct: 368 PTTIKSAPTTPKEP----APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 423 Query: 493 LDLNKVFQPSVPATKSGLLPPP---------------PALPPRPCPSQSEQV--SEAELL 535 + P PA + P P P P P P+ E + E Sbjct: 424 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 483 Query: 536 PQLSRAPSQAAESSPAKKDVLYSQP----------PSKPIRRKFRPENQATENQEPSTAA 585 P + P+ PA P P +P + T+ P+T Sbjct: 484 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 543 Query: 586 SGPASAATMKPHPTVQKQSSKQKKAIQTAIRK 617 S P + P T + + K+ T +K Sbjct: 544 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK 575 Score = 48.5 bits (114), Expect = 2e-05 Identities = 57/255 (22%), Positives = 90/255 (35%), Gaps = 21/255 (8%) Query: 360 PPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADL------P 413 P P +++A PK + + P P T+ K+ A P Sbjct: 363 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 422 Query: 414 VPNQDVTSDDKQALKSTINEALPKDVSED-PATPKDSNSLKARPRSRSYSSTSIEEAMKR 472 + + K+ +T + P E P TPK+ + + T+ E A Sbjct: 423 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA----PTTKEPAPTT 478 Query: 473 GEDP-PTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPS--QSEQV 529 ++P PT P +P T + + K +P+ TK P P P P P+ +S Sbjct: 479 PKEPAPTAPKKPAPTTPKEPAPTTPK--EPAPTTTKE----PSPTTPKEPAPTTTKSAPT 532 Query: 530 SEAELLPQLSR-APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGP 588 + E P ++ AP+ E SP P +P + T + T P Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 592 Query: 589 ASAATMKPHPTVQKQ 603 A T KP PT K+ Sbjct: 593 APTTTKKPAPTTPKE 607 Score = 44.7 bits (104), Expect = 3e-04 Identities = 42/191 (21%), Positives = 67/191 (35%), Gaps = 21/191 (10%) Query: 415 PNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGE 474 P + + K+ +T E P P TPK+ P+ + ++ E Sbjct: 448 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP--APTAPKKPAPTTPK--------E 497 Query: 475 DPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAEL 534 PT P P T ++ S K +P+ TKS P P P ++S + E Sbjct: 498 PAPTTPKEPAPTTTKEPSPTTPK--EPAPTTTKSA---PTTTKEPAPTTTKSAPTTPKEP 552 Query: 535 LPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATM 594 P ++ P+ PA P KP + T + T PA Sbjct: 553 SPTTTKEPAPTTPKEPAPTT------PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 606 Query: 595 KPHPTVQKQSS 605 +P PT K+++ Sbjct: 607 EPAPTTPKETA 617 Score = 43.9 bits (102), Expect = 5e-04 Identities = 60/272 (22%), Positives = 88/272 (32%), Gaps = 49/272 (18%) Query: 356 PEGLPPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMADLPVP 415 PE L PT E +P + + P P T+ K+ A P Sbjct: 645 PEELAPTTPEEPTPTTPEEP----------APTTPKAAAPNTPKEPAPTTPKEPAPT-TP 693 Query: 416 NQDVTSDDKQALKSTINEALPKDVSED-PATPKDSNSLKARPRSRSYSSTSIEEAMKRGE 474 + + K+ +T P + E P TPK +P + + T+ +E Sbjct: 694 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK-------KPAPKELAPTTTKEPTSTTC 746 Query: 475 DPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLP-----PPPALPPRPCPSQSEQV 529 D P P P+ T + P T G P P P P +P P Sbjct: 747 DKPAPTT-PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK----- 800 Query: 530 SEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPS-TAASGP 588 EL P ++ P+ PA P+ P E T +EP+ T P Sbjct: 801 ---ELAPTTTKGPTSTTSDKPA---------PTTP------KETAPTTPKEPAPTTPKKP 842 Query: 589 ASAATMKPHPTVQKQSSKQKKAIQTAIRKNKE 620 A P PT + S+ T I K+ + Sbjct: 843 APTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 874 Score = 43.1 bits (100), Expect = 8e-04 Identities = 41/186 (22%), Positives = 65/186 (34%), Gaps = 16/186 (8%) Query: 415 PNQDVTSDDKQALKSTINEALPKDVSE-DPATPKDSNSLKARPRSRSYSSTSIEEAMKRG 473 P + + K+ +T E P E P TPK+ A ++S +T+ E A Sbjct: 487 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP----APTTTKSAPTTTKEPAPTTT 542 Query: 474 EDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAE 533 + PT P P T ++ + K P+ P P P P P P+ ++ + Sbjct: 543 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK------PAPTTPKEPAPTTPKEPA--- 593 Query: 534 LLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAAT 593 P ++ P+ PA + P + PE A E + A T Sbjct: 594 --PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 651 Query: 594 MKPHPT 599 PT Sbjct: 652 TPEEPT 657 Score = 42.4 bits (98), Expect = 0.001 Identities = 42/197 (21%), Positives = 73/197 (37%), Gaps = 12/197 (6%) Query: 413 PVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKR 472 P P+ SD + T+N+ + E T K +++ + + + SIE+ + Sbjct: 260 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 319 Query: 473 GEDPPT-----PPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSE 527 P + P P+ + T ++ +L K P+ P + P P P +S Sbjct: 320 DLAPTSKVLAKPTPKAETT-TKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIKSA 374 Query: 528 QVSEAELLPQLSR-APSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAAS 586 + E P ++ AP+ E +P P +P + T P+T Sbjct: 375 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 434 Query: 587 GPASAATMKPHPTVQKQ 603 PA KP PT K+ Sbjct: 435 -PAPTTPKKPAPTTPKE 450 Score = 39.7 bits (91), Expect = 0.009 Identities = 45/232 (19%), Positives = 73/232 (31%), Gaps = 25/232 (10%) Query: 390 PANQQPRDLNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDS 449 P P T+ K + T+ +K A T E L E+P Sbjct: 605 PKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA--PTTPEELAPTTPEEPTPTTPE 662 Query: 450 NSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSG 509 P++ + ++ E PT P P T + ++ K P+ Sbjct: 663 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT------ 716 Query: 510 LLPPPPALPPRPCPSQSEQVSEAE----------------LLPQLSRAPSQAAESSPAKK 553 L P P P +P P + + E P + P+ PA Sbjct: 717 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 776 Query: 554 DVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSS 605 + P + P+ A + P+T GP S + KP PT K+++ Sbjct: 777 TPKGTAPTTLKEPAPTTPKKPAPKELAPTT-TKGPTSTTSDKPAPTTPKETA 827 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 48.9 bits (115), Expect = 1e-05 Identities = 65/267 (24%), Positives = 99/267 (37%), Gaps = 28/267 (10%) Query: 411 DLPVPNQDVTSDDKQALKSTIN-------EALP--KDVSEDPATPKDSNSLKARPRSRSY 461 +LP P+ V Q ST + E +P K+ S + + K+ K RPRSRS Sbjct: 222 ELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSR 281 Query: 462 SSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPA-----TKSGLLPPPPA 516 S + + R P PR ++ SR+ S + P T +PPPP Sbjct: 282 SKS---RSRTRSRSPSHTRPR-RRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPR 337 Query: 517 LPPRPCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSK---------PIRR 567 P + + S A L S + S + S P K S PP K P RR Sbjct: 338 HRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRR 397 Query: 568 KFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLAR 627 + RP AT + + + S T K +V + K K + + Sbjct: 398 RHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKP 457 Query: 628 LNSELQQQLKEVHQERIALENQLEQLR 654 EL + +E ++A + ++Q R Sbjct: 458 RKVELSES-EEDKGGKMAAADSVQQRR 483 Score = 44.7 bits (104), Expect = 3e-04 Identities = 53/213 (24%), Positives = 77/213 (36%), Gaps = 19/213 (8%) Query: 428 KSTINEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDP-----PTPPPR 482 K ++ + P P T + S SL ++ R S S S EA R P P+P PR Sbjct: 632 KRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREA--RSPQPNKRHSPSPRPR 689 Query: 483 PQKTHS------RASSLDLNKVFQPSV---PATKSGLLPPPPALPPRPCPSQSEQVSEAE 533 +T S R +S + PS P + P P + PS + V Sbjct: 690 APQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSP-QSVRRVS 748 Query: 534 LLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAAT 593 +S +P AA+ PA + SQ PS + + PS + Sbjct: 749 SSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGG 808 Query: 594 MKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLA 626 K K+ K KK +K+K+ AV A Sbjct: 809 KKKKKKKDKKHKKDKK--HKKHKKHKKEKAVAA 839 Score = 43.5 bits (101), Expect = 6e-04 Identities = 100/474 (21%), Positives = 165/474 (34%), Gaps = 69/474 (14%) Query: 169 EKNSFKRMDDE-----DKQETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHP 223 EKNS K + E + ++S + + SP + P + S YS R + + P Sbjct: 262 EKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRP 321 Query: 224 APYEARQPLVQP---EGSSSGGPGTKPLRHQASLIRSFSVERELQDNSSYPDEPWRITEE 280 +P P P S P + R ASL S S + S P R + Sbjct: 322 SPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSP 381 Query: 281 QREYYVNQFRSLQPD---PSSFISGSVAKNFFTKSKLS-IPELSYIWELSDADCDGALTL 336 R+ R L P P S K++ S P+ S S T Sbjct: 382 PRKT-----RRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTS 436 Query: 337 PEFCAAFHLIVARKNGYPLPEGLPPTLQPEYLQAAFPKPKWDCQLFDSYSESLPANQQPR 396 + V + G E P +P ++ + + ++ + S QQ R Sbjct: 437 GK--------VTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSV-----QQRR 483 Query: 397 DLNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTI-NEALPKDVSEDPATPKDSNSLKAR 455 R + S D +S+D++ +S + N + + P+ + K + Sbjct: 484 QYRRQNQQSSSDSGS------SSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQ 537 Query: 456 ----PRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLL 511 PR R S S +R P PPPR ++T P+ P + Sbjct: 538 KETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRT--------------PTPPPRRRTPS 583 Query: 512 PPPPALPPRP---CPSQSEQVSEAELLPQLSRAP-----SQAAESSPAKKDVLYSQPP-- 561 PPP P P P + S + + + +P +A+ S P K+ V +S PP Sbjct: 584 PPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQ 643 Query: 562 -SKPIRRKFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTA 614 S P+ ++ P + + S + S + P P + S + +A QT+ Sbjct: 644 RSSPVTKRRSPSLSSKHRKGSSPSRS---TREARSPQPNKRHSPSPRPRAPQTS 694 Score = 34.7 bits (78), Expect = 0.29 Identities = 53/238 (22%), Positives = 96/238 (40%), Gaps = 34/238 (14%) Query: 409 MADLPVPNQDVTSDDKQALKSTINEA----LPKDVSEDPATPKDSNSLKARPRSRSYSST 464 +A + ++D DK+ +S+ + P+ +P+ +S R R RS+S + Sbjct: 141 LASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRS 200 Query: 465 SIEEAMKRGEDPPTPPPRPQKTHSRASSLDLN-KVFQPSVP---ATKSGLLPPPPALPPR 520 R +P P P+K + + KV +PSV +T L P P P Sbjct: 201 PRHRTKSR-----SPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPE 255 Query: 521 PCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPS--KPIR------RKFRPE 572 P E+ S+ E + +R S++ S ++ S+ PS +P R R + P Sbjct: 256 PKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSR---TRSRSPSHTRPRRRHRSRSRSYSPR 312 Query: 573 NQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNS 630 + + + PS P M P P ++ S +R+ + ++A L+ +S Sbjct: 313 RRPSPRRRPSPRRRTP--PRRMPPPPRHRRSRS--------PVRRRRRSSASLSGSSS 360 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 48.5 bits (114), Expect = 2e-05 Identities = 48/209 (22%), Positives = 72/209 (34%), Gaps = 4/209 (1%) Query: 386 SESLPANQQPRDLNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPAT 445 S SL ++ P S + P QAL+ + P PA Sbjct: 230 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP--QVTPPRKDAAPAL 287 Query: 446 PKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPA 505 S+S A P + S S +++ PP PP T + +L F PS P Sbjct: 288 GPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL 347 Query: 506 TKSGLLPP--PPALPPRPCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYSQPPSK 563 + PP PPAL P + + L P + +P + +S PPS Sbjct: 348 SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 407 Query: 564 PIRRKFRPENQATENQEPSTAASGPASAA 592 P++ F P + + + P S A Sbjct: 408 PVQAPFSPPASPPVSPSATPPSQAPPSLA 436 Score = 33.1 bits (74), Expect = 0.84 Identities = 40/161 (24%), Positives = 55/161 (34%), Gaps = 28/161 (17%) Query: 473 GEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEA 532 G P TP P + SRA+ ++ +P P PP PR S + + S Sbjct: 157 GPTPGTPSPAMAR-RSRAAGTEVG------LPRPAPSARPRPPTEGPRKSVSSASEHSTT 209 Query: 533 ELLPQLSRAPSQAAE-SSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASA 591 E P R PS PA + + S P S A SGP++ Sbjct: 210 EPSPAARRRPSAGGGLQRPASRSLSSSATPLS------------------SPARSGPSAR 251 Query: 592 ATMK--PHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNS 630 T + HP+ K Q K+A L L+S Sbjct: 252 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 292 Score = 32.7 bits (73), Expect = 1.1 Identities = 38/166 (22%), Positives = 52/166 (31%), Gaps = 14/166 (8%) Query: 445 TPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKV------ 498 +P+ N+L +S P +PP P T + L Sbjct: 385 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 444 Query: 499 FQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLSRAPSQAAESSPAK--KDVL 556 P+ P PPP A PP P + P L+ P QA S PA Sbjct: 445 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 504 Query: 557 YSQPPSKPIRRKFRPENQATE------NQEPSTAASGPASAATMKP 596 +S S P+ P QA Q P + + P A +P Sbjct: 505 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP 550 Score = 29.6 bits (65), Expect = 9.2 Identities = 24/73 (32%), Positives = 29/73 (39%), Gaps = 2/73 (2%) Query: 182 QETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSSSG 241 Q SP SP SP ++PP PL+ +L Q PA A PL + Sbjct: 441 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA--LATPPLQALPSPPAS 498 Query: 242 GPGTKPLRHQASL 254 PG P ASL Sbjct: 499 FPGQAPFSPSASL 511 >gi|163659920 pannexin 2 isoform 1 [Homo sapiens] Length = 677 Score = 48.1 bits (113), Expect = 3e-05 Identities = 50/204 (24%), Positives = 81/204 (39%), Gaps = 23/204 (11%) Query: 435 LPKDVSEDPATPKDSNSLKARP---RSRSYSSTSIEEAMKR--------GEDP------- 476 LP+ E A + NS +P R ++ + T I + R G DP Sbjct: 439 LPQPFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRSAHHYKGGGGDPGPGPAPA 498 Query: 477 PTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLP 536 P PPP P K H+R SLD++ P + TK PA P + +S+AE Sbjct: 499 PAPPPAPDKKHARHFSLDVH----PYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDC- 553 Query: 537 QLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASAATMKP 596 L AP+ ++ +K++ Y P++ P + + P+ A PAS +P Sbjct: 554 GLGLAPAPIKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTPASLGKAEP 613 Query: 597 HPTVQKQSSKQKKAIQTAIRKNKE 620 + + ++ I T +E Sbjct: 614 LTILSRNATHPLLHINTLYEAREE 637 >gi|40353727 synaptopodin isoform A [Homo sapiens] Length = 903 Score = 48.1 bits (113), Expect = 3e-05 Identities = 61/219 (27%), Positives = 91/219 (41%), Gaps = 19/219 (8%) Query: 390 PANQQPRDL-NRMEKTSVKDMADLPVPNQD----VTSDDKQALKST-INEALPKDVSEDP 443 PA DL + K ++ LP P++ TS + +L+ T ++ D+S P Sbjct: 590 PAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDIS--P 647 Query: 444 ATPKDSNSLKARPRSRSYSSTSIE--EAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQP 501 +P + S +A+ R ST EA R E PT PP SSLD P Sbjct: 648 VSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGP 707 Query: 502 SVPATKSGLLPPPPALPPRP-CPSQSEQVSEAELLPQL-SRAPSQAAESSPAKKDVLYSQ 559 P S + PPP PP P PS SE+ S + L P+ +R PS+ ++ A+ + ++ Sbjct: 708 WEPGRGSSMSSPPPLPPPPPMSPSWSER-SVSPLRPETEARPPSRQLQALLARNIINAAR 766 Query: 560 PPSKPIRRKFRPENQATENQEPSTAASGPASAATMKPHP 598 R+ P + EN P + P P P Sbjct: 767 ------RKSASPRSAGAENPRPFSPPRAPPPPPPPPPPP 799 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 47.8 bits (112), Expect = 3e-05 Identities = 39/154 (25%), Positives = 58/154 (37%), Gaps = 4/154 (2%) Query: 443 PATPKDSNSL--KARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQ 500 PATP S+ A P + S S +++ PP PP T + +L F Sbjct: 322 PATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL 381 Query: 501 PSVPATKSGLLPP--PPALPPRPCPSQSEQVSEAELLPQLSRAPSQAAESSPAKKDVLYS 558 PS P + PP PPAL P + + L P + +P + +S Sbjct: 382 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 441 Query: 559 QPPSKPIRRKFRPENQATENQEPSTAASGPASAA 592 PPS P++ F P + + + P S A Sbjct: 442 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 475 Score = 33.1 bits (74), Expect = 0.84 Identities = 40/161 (24%), Positives = 55/161 (34%), Gaps = 28/161 (17%) Query: 473 GEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEA 532 G P TP P + SRA+ ++ +P P PP PR S + + S Sbjct: 166 GPTPGTPSPAMAR-RSRAAGTEVG------LPRPAPSARPRPPTEGPRKSVSSASEHSTT 218 Query: 533 ELLPQLSRAPSQAAE-SSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASA 591 E P R PS PA + + S P S A SGP++ Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLS------------------SPARSGPSAR 260 Query: 592 ATMK--PHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNS 630 T + HP+ K Q K+A L L+S Sbjct: 261 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301 Score = 32.7 bits (73), Expect = 1.1 Identities = 38/166 (22%), Positives = 52/166 (31%), Gaps = 14/166 (8%) Query: 445 TPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKV------ 498 +P+ N+L +S P +PP P T + L Sbjct: 424 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 483 Query: 499 FQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLSRAPSQAAESSPAK--KDVL 556 P+ P PPP A PP P + P L+ P QA S PA Sbjct: 484 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543 Query: 557 YSQPPSKPIRRKFRPENQATE------NQEPSTAASGPASAATMKP 596 +S S P+ P QA Q P + + P A +P Sbjct: 544 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP 589 Score = 29.6 bits (65), Expect = 9.2 Identities = 24/73 (32%), Positives = 29/73 (39%), Gaps = 2/73 (2%) Query: 182 QETQSPTMSPLASPPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEARQPLVQPEGSSSG 241 Q SP SP SP ++PP PL+ +L Q PA A PL + Sbjct: 480 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA--LATPPLQALPSPPAS 537 Query: 242 GPGTKPLRHQASL 254 PG P ASL Sbjct: 538 FPGQAPFSPSASL 550 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.127 0.368 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,344,335 Number of Sequences: 37866 Number of extensions: 1887865 Number of successful extensions: 21161 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 231 Number of HSP's successfully gapped in prelim test: 1158 Number of HSP's that attempted gapping in prelim test: 14131 Number of HSP's gapped (non-prelim): 6048 length of query: 659 length of database: 18,247,518 effective HSP length: 109 effective length of query: 550 effective length of database: 14,120,124 effective search space: 7766068200 effective search space used: 7766068200 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.