BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|124494238 myosin IC isoform a [Homo sapiens] (1063 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|124494238 myosin IC isoform a [Homo sapiens] 2122 0.0 gi|124494247 myosin IC isoform b [Homo sapiens] 2071 0.0 gi|124494240 myosin IC isoform c [Homo sapiens] 2053 0.0 gi|254028267 myosin 1H [Homo sapiens] 1286 0.0 gi|44889481 myosin IB isoform 2 [Homo sapiens] 802 0.0 gi|4885503 myosin IA [Homo sapiens] 789 0.0 gi|194328685 myosin IB isoform 1 [Homo sapiens] 743 0.0 gi|240120050 myosin IB isoform 1 [Homo sapiens] 743 0.0 gi|51100974 myosin ID [Homo sapiens] 697 0.0 gi|239582755 myosin IG [Homo sapiens] 658 0.0 gi|27544941 myosin IF [Homo sapiens] 612 e-175 gi|55956916 myosin IE [Homo sapiens] 608 e-174 gi|122937512 myosin VIIB [Homo sapiens] 514 e-145 gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 505 e-142 gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 505 e-142 gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 505 e-142 gi|154354979 myosin X [Homo sapiens] 483 e-136 gi|153945715 myosin VC [Homo sapiens] 480 e-135 gi|118402590 myosin XV [Homo sapiens] 467 e-131 gi|215982794 myosin VA isoform 2 [Homo sapiens] 453 e-127 gi|215982791 myosin VA isoform 1 [Homo sapiens] 453 e-127 gi|122937345 myosin VB [Homo sapiens] 450 e-126 gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 444 e-124 gi|156104908 myosin heavy chain 6 [Homo sapiens] 444 e-124 gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 435 e-121 gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 434 e-121 gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 431 e-120 gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 431 e-120 gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 429 e-120 gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 429 e-120 >gi|124494238 myosin IC isoform a [Homo sapiens] Length = 1063 Score = 2122 bits (5498), Expect = 0.0 Identities = 1063/1063 (100%), Positives = 1063/1063 (100%) Query: 1 MALQVELVPTGEIIRVVHPHRPCKLALGSDGVRVTMESALTARDRVGVQDFVLLENFTSE 60 MALQVELVPTGEIIRVVHPHRPCKLALGSDGVRVTMESALTARDRVGVQDFVLLENFTSE Sbjct: 1 MALQVELVPTGEIIRVVHPHRPCKLALGSDGVRVTMESALTARDRVGVQDFVLLENFTSE 60 Query: 61 AAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFAVA 120 AAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFAVA Sbjct: 61 AAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFAVA 120 Query: 121 DTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERGGAVRDRLLQSNPV 180 DTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERGGAVRDRLLQSNPV Sbjct: 121 DTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERGGAVRDRLLQSNPV 180 Query: 181 LEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHIF 240 LEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHIF Sbjct: 181 LEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHIF 240 Query: 241 YQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALTVIDFTEDE 300 YQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALTVIDFTEDE Sbjct: 241 YQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALTVIDFTEDE 300 Query: 301 VEDLLSIVASVLHLGNIHFAANEESNAQVTTENQLKYLTRLLSVEGSTLREALTHRKIIA 360 VEDLLSIVASVLHLGNIHFAANEESNAQVTTENQLKYLTRLLSVEGSTLREALTHRKIIA Sbjct: 301 VEDLLSIVASVLHLGNIHFAANEESNAQVTTENQLKYLTRLLSVEGSTLREALTHRKIIA 360 Query: 361 KGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLASKDVESPSWRSTTVLGLL 420 KGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLASKDVESPSWRSTTVLGLL Sbjct: 361 KGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLASKDVESPSWRSTTVLGLL 420 Query: 421 DIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPVQYFNNKIIC 480 DIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPVQYFNNKIIC Sbjct: 421 DIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPVQYFNNKIIC 480 Query: 481 DLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPHFLTHKLADQRTRKSLGRG 540 DLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPHFLTHKLADQRTRKSLGRG Sbjct: 481 DLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPHFLTHKLADQRTRKSLGRG 540 Query: 541 EFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMSQCFDRSELSDKKRPETV 600 EFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMSQCFDRSELSDKKRPETV Sbjct: 541 EFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMSQCFDRSELSDKKRPETV 600 Query: 601 ATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRA 660 ATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRA Sbjct: 601 ATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRA 660 Query: 661 GFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFP 720 GFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFP Sbjct: 661 GFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFP 720 Query: 721 KTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKR 780 KTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKR Sbjct: 721 KTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKR 780 Query: 781 KWAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTSFLLNLRRQLPQNVLDTSWPTPPPAL 840 KWAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTSFLLNLRRQLPQNVLDTSWPTPPPAL Sbjct: 781 KWAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTSFLLNLRRQLPQNVLDTSWPTPPPAL 840 Query: 841 REASELLRELCIKNMVWKYCRSISPEWKQQLQQKAVASEIFKGKKDNYPQSVPRLFISTR 900 REASELLRELCIKNMVWKYCRSISPEWKQQLQQKAVASEIFKGKKDNYPQSVPRLFISTR Sbjct: 841 REASELLRELCIKNMVWKYCRSISPEWKQQLQQKAVASEIFKGKKDNYPQSVPRLFISTR 900 Query: 901 LGTDEISPRVLQALGSEPIQYAVPVVKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQRID 960 LGTDEISPRVLQALGSEPIQYAVPVVKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQRID Sbjct: 901 LGTDEISPRVLQALGSEPIQYAVPVVKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQRID 960 Query: 961 YANLTGISVSSLSDSLFVLHVQRADNKQKGDVVLQSDHVIETLTKTALSANRVNSININQ 1020 YANLTGISVSSLSDSLFVLHVQRADNKQKGDVVLQSDHVIETLTKTALSANRVNSININQ Sbjct: 961 YANLTGISVSSLSDSLFVLHVQRADNKQKGDVVLQSDHVIETLTKTALSANRVNSININQ 1020 Query: 1021 GSITFAGGPGRDGTIDFTPGSELLITKAKNGHLAVVAPRLNSR 1063 GSITFAGGPGRDGTIDFTPGSELLITKAKNGHLAVVAPRLNSR Sbjct: 1021 GSITFAGGPGRDGTIDFTPGSELLITKAKNGHLAVVAPRLNSR 1063 >gi|124494247 myosin IC isoform b [Homo sapiens] Length = 1044 Score = 2071 bits (5366), Expect = 0.0 Identities = 1038/1038 (100%), Positives = 1038/1038 (100%) Query: 26 ALGSDGVRVTMESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLV 85 ALGSDGVRVTMESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLV Sbjct: 7 ALGSDGVRVTMESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLV 66 Query: 86 SVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAG 145 SVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAG Sbjct: 67 SVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAG 126 Query: 146 KTEATKRLLQFYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQ 205 KTEATKRLLQFYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQ Sbjct: 127 KTEATKRLLQFYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQ 186 Query: 206 FDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYL 265 FDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYL Sbjct: 187 FDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYL 246 Query: 266 YLVKGQCAKVSSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEES 325 YLVKGQCAKVSSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEES Sbjct: 247 YLVKGQCAKVSSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEES 306 Query: 326 NAQVTTENQLKYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAV 385 NAQVTTENQLKYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAV Sbjct: 307 NAQVTTENQLKYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAV 366 Query: 386 YSRTFTWLVGKINRSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKL 445 YSRTFTWLVGKINRSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKL Sbjct: 367 YSRTFTWLVGKINRSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKL 426 Query: 446 QQLFIELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEAT 505 QQLFIELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEAT Sbjct: 427 QQLFIELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEAT 486 Query: 506 DLTFLEKLEDTVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDL 565 DLTFLEKLEDTVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDL Sbjct: 487 DLTFLEKLEDTVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDL 546 Query: 566 LFRNLKETMCSSKNPIMSQCFDRSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRC 625 LFRNLKETMCSSKNPIMSQCFDRSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRC Sbjct: 547 LFRNLKETMCSSKNPIMSQCFDRSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRC 606 Query: 626 IKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPT 685 IKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPT Sbjct: 607 IKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPT 666 Query: 686 WAGRPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAW 745 WAGRPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAW Sbjct: 667 WAGRPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAW 726 Query: 746 RGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPEN 805 RGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPEN Sbjct: 727 RGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPEN 786 Query: 806 AFFLDHVRTSFLLNLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISP 865 AFFLDHVRTSFLLNLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISP Sbjct: 787 AFFLDHVRTSFLLNLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISP 846 Query: 866 EWKQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQALGSEPIQYAVPV 925 EWKQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQALGSEPIQYAVPV Sbjct: 847 EWKQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQALGSEPIQYAVPV 906 Query: 926 VKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQRIDYANLTGISVSSLSDSLFVLHVQRAD 985 VKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQRIDYANLTGISVSSLSDSLFVLHVQRAD Sbjct: 907 VKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQRIDYANLTGISVSSLSDSLFVLHVQRAD 966 Query: 986 NKQKGDVVLQSDHVIETLTKTALSANRVNSININQGSITFAGGPGRDGTIDFTPGSELLI 1045 NKQKGDVVLQSDHVIETLTKTALSANRVNSININQGSITFAGGPGRDGTIDFTPGSELLI Sbjct: 967 NKQKGDVVLQSDHVIETLTKTALSANRVNSININQGSITFAGGPGRDGTIDFTPGSELLI 1026 Query: 1046 TKAKNGHLAVVAPRLNSR 1063 TKAKNGHLAVVAPRLNSR Sbjct: 1027 TKAKNGHLAVVAPRLNSR 1044 >gi|124494240 myosin IC isoform c [Homo sapiens] Length = 1028 Score = 2053 bits (5318), Expect = 0.0 Identities = 1028/1028 (100%), Positives = 1028/1028 (100%) Query: 36 MESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQI 95 MESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQI Sbjct: 1 MESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQI 60 Query: 96 YSRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQ 155 YSRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQ Sbjct: 61 YSRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQ 120 Query: 156 FYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGG 215 FYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGG Sbjct: 121 FYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGG 180 Query: 216 HILSYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKV 275 HILSYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKV Sbjct: 181 HILSYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKV 240 Query: 276 SSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQL 335 SSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQL Sbjct: 241 SSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQL 300 Query: 336 KYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVG 395 KYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVG Sbjct: 301 KYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVG 360 Query: 396 KINRSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLK 455 KINRSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLK Sbjct: 361 KINRSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLK 420 Query: 456 SEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLED 515 SEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLED Sbjct: 421 SEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLED 480 Query: 516 TVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMC 575 TVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMC Sbjct: 481 TVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMC 540 Query: 576 SSKNPIMSQCFDRSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPG 635 SSKNPIMSQCFDRSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPG Sbjct: 541 SSKNPIMSQCFDRSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPG 600 Query: 636 RFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVA 695 RFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVA Sbjct: 601 RFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVA 660 Query: 696 VLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFL 755 VLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFL Sbjct: 661 VLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFL 720 Query: 756 RVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTS 815 RVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTS Sbjct: 721 RVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTS 780 Query: 816 FLLNLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISPEWKQQLQQKA 875 FLLNLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISPEWKQQLQQKA Sbjct: 781 FLLNLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISPEWKQQLQQKA 840 Query: 876 VASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQALGSEPIQYAVPVVKYDRKGYKP 935 VASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQALGSEPIQYAVPVVKYDRKGYKP Sbjct: 841 VASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQALGSEPIQYAVPVVKYDRKGYKP 900 Query: 936 RSRQLLLTPNAVVIVEDAKVKQRIDYANLTGISVSSLSDSLFVLHVQRADNKQKGDVVLQ 995 RSRQLLLTPNAVVIVEDAKVKQRIDYANLTGISVSSLSDSLFVLHVQRADNKQKGDVVLQ Sbjct: 901 RSRQLLLTPNAVVIVEDAKVKQRIDYANLTGISVSSLSDSLFVLHVQRADNKQKGDVVLQ 960 Query: 996 SDHVIETLTKTALSANRVNSININQGSITFAGGPGRDGTIDFTPGSELLITKAKNGHLAV 1055 SDHVIETLTKTALSANRVNSININQGSITFAGGPGRDGTIDFTPGSELLITKAKNGHLAV Sbjct: 961 SDHVIETLTKTALSANRVNSININQGSITFAGGPGRDGTIDFTPGSELLITKAKNGHLAV 1020 Query: 1056 VAPRLNSR 1063 VAPRLNSR Sbjct: 1021 VAPRLNSR 1028 >gi|254028267 myosin 1H [Homo sapiens] Length = 1022 Score = 1286 bits (3329), Expect = 0.0 Identities = 624/1027 (60%), Positives = 794/1027 (77%), Gaps = 5/1027 (0%) Query: 36 MESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQI 95 ME ALTARD+VGVQDFVLL+ +TSE+AF++NLR+RF ENLIYTYIG +LVSVNPY++L I Sbjct: 1 MEGALTARDKVGVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGI 60 Query: 96 YSRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQ 155 Y+ ME Y+GV+F+E+PPH++A+AD YR + E + ++ISGESGAGKTEA+K++L+ Sbjct: 61 YTVSQMELYQGVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILE 120 Query: 156 FYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGG 215 ++A TCP + RDRLL SNPVLEAFGNA+TLRNDNSSRFGKYMD+QFDF+G PVGG Sbjct: 121 YFAVTCPMTQSLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGG 180 Query: 216 HILSYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKV 275 HI+SYL+EKSRVV+QN GERNFHIFYQLL GGEEE L LGLER+PQ Y YL +G CAK Sbjct: 181 HIISYLIEKSRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKE 240 Query: 276 SSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQL 335 SSI+DK+DWK V A +VIDFTE ++E+L I+ASVLHLGNI F +++ A + +++ Sbjct: 241 SSISDKNDWKTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPDTHEI 300 Query: 336 KYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVG 395 K++ +LL V S L EALTHRKI AK EE++ PL LE + YARDA+AKAVY RTFTWLV Sbjct: 301 KWIAKLLGVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVN 360 Query: 396 KINRSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLK 455 KIN SL +KD + TV+GLLDIYGFEVF N FEQFCINYCNEKLQQL IE TLK Sbjct: 361 KINSSLVNKD-----FTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLK 415 Query: 456 SEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLED 515 +EQ EYE EGI WEP++YFNNKIICDLVEE+ KGIISILDEEC+RPG ATDL+FLEKLE+ Sbjct: 416 AEQAEYEMEGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEE 475 Query: 516 TVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMC 575 V H HF T KLA + RK +G EFRLLHYAGEVTY GFL+KNNDLL+R+LKE +C Sbjct: 476 KVGKHAHFETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLC 535 Query: 576 SSKNPIMSQCFDRSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPG 635 SKN I+ +CF +EL +++RP TV TQFK SL L+E L SKEP+Y+RCIKPND K+P Sbjct: 536 KSKNIILRECFLLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPS 595 Query: 636 RFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVA 695 +FD+ LIRHQ+KYLGL+E+LRVRRAGFAYRRKYE FLQRYKSLCP+TWP W G P +GV Sbjct: 596 KFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVE 655 Query: 696 VLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFL 755 L++++GYKPEEYK+G+TKIFIRFP+TLFATEDA E + L +IQA ++ R++++ Sbjct: 656 RLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYV 715 Query: 756 RVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTS 815 + +++AI +++ WRG L R+ +RKWA + IR+ I+GF+ R+ P CP+N F+ VR + Sbjct: 716 KKRQAAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEFIVFVRKN 775 Query: 816 FLLNLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISPEWKQQLQQKA 875 ++LNLR LP+ VLD SW PP L AS+LLR++C++N+V KYCR I+ E K +QQK Sbjct: 776 YILNLRYHLPKTVLDKSWLRPPGILENASDLLRKMCVRNLVQKYCRGITAERKAMMQQKV 835 Query: 876 VASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQALGSEPIQYAVPVVKYDRKGYKP 935 V SEIF+G+KD Y +S+ + F+++R+ +I+P+VLQ + E IQY VPV+KYDRKG+K Sbjct: 836 VTSEIFRGRKDGYTESLNQPFVNSRIDEGDINPKVLQLISHEKIQYGVPVIKYDRKGFKA 895 Query: 936 RSRQLLLTPNAVVIVEDAKVKQRIDYANLTGISVSSLSDSLFVLHVQRADNKQKGDVVLQ 995 R RQL+LT A +VE AK+KQ+I+Y+ L G+S S+LSD + V+HV D+KQKGD VLQ Sbjct: 896 RQRQLILTQKAAYVVELAKIKQKIEYSALKGVSTSNLSDGILVIHVSPEDSKQKGDAVLQ 955 Query: 996 SDHVIETLTKTALSANRVNSININQGSITFAGGPGRDGTIDFTPGSELLITKAKNGHLAV 1055 HV E +TK + + N +N+ QGS+ F PG++GTI F G E + K KNG L V Sbjct: 956 CGHVFEAVTKLVMLVKKENIVNVVQGSLQFFISPGKEGTIVFDTGLEEQVYKNKNGQLTV 1015 Query: 1056 VAPRLNS 1062 V+ R S Sbjct: 1016 VSVRRKS 1022 >gi|44889481 myosin IB isoform 2 [Homo sapiens] Length = 1078 Score = 802 bits (2072), Expect = 0.0 Identities = 452/1014 (44%), Positives = 625/1014 (61%), Gaps = 64/1014 (6%) Query: 46 VGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYR 105 +GV D VLLE E FI NL++RF + IYTYIG V++SVNPYR L IYS + +E YR Sbjct: 15 IGVGDMVLLEPLNEET-FINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYR 73 Query: 106 GVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPE 165 +FYE+ PH+FA++D YR+LR + +DQ ++I+GESGAGKTEA+K ++ + A C Sbjct: 74 NRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGA 133 Query: 166 RGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKS 225 V+++LLQSNPVLEAFGNAKT+RNDNSSRFGKYMD++FDFKG P+GG I +YLLEKS Sbjct: 134 EVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKS 193 Query: 226 RVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWK 285 RVV Q GERNFH+FYQLL G EE L +L LER+ Y YL AKV+ ++D ++++ Sbjct: 194 RVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDS-AKVNGVDDAANFR 252 Query: 286 VVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN----AQVTTENQLKYLTRL 341 VR A+ ++ F + E E +L++VA+VL LGNI F N +++ +N+LK + L Sbjct: 253 TVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICEL 312 Query: 342 LSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL 401 ++ S L A + R + AK E++ + LN+ QA YARDALAK +YSR F+WLV +IN S+ Sbjct: 313 TGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESI 372 Query: 402 ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEY 461 ++ V+G+LDIYGFE+F+ NSFEQF INYCNEKLQQ+FIELTLK EQEEY Sbjct: 373 KAQTKVRKK-----VMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEY 427 Query: 462 EAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHP 521 E I W + YFNN IICDL+E GI+++LDEECLRPG TD TFLEKL H Sbjct: 428 IREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQ 487 Query: 522 HFLTHKLADQR--TRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKN 579 HF + R SL FR+ HYAG+V Y V GF+DKNNDLL+R+L + M + + Sbjct: 488 HFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASH 547 Query: 580 PIMSQCFDRSELS--DKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRF 637 ++ F + + KRP T +QFK S+ L++ LQ+K P Y+RCIKPND K F Sbjct: 548 ALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIF 607 Query: 638 DEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVL 697 +E L+ HQ++YLGLLEN+RVRRAG+A+R+ YE L+RYK LC +TWP W G + GV VL Sbjct: 608 NEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVL 667 Query: 698 VRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRV 757 L EEY GR+KIFIR P+TLF ED + R + LAT IQ +RG+ R FL + Sbjct: 668 FNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLM 727 Query: 758 KRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFV-------LRHAPRCPE------ 804 K+S I I +W+R +++ + K +A I+ IRG+ L+H RC E Sbjct: 728 KKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIA 787 Query: 805 ------------------NA------FFLDHVRTSFLLNLRRQLPQ-NVLDTSWPTPPPA 839 NA F L + + L ++ ++P + +D +WP+ P Sbjct: 788 AYWHGTQVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKMPSLSPIDKNWPSRPYL 847 Query: 840 LREASELLRELCIKNMVW---KYCRSISPEWKQQLQQKAVASEIFKGKKDNYPQSVPRLF 896 +++ +EL +W KY + + K ++K ASE+FK KK YP SV + F Sbjct: 848 FLDSTH--KELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPF 905 Query: 897 ISTRLGTDEISPRV--LQALGSEPIQYAVPVVKYDRKGYKPRSRQLLLTPNAVVIVE--D 952 L ++ +P+ L+ E I A V K +R K SR LLT N +++ + Sbjct: 906 QGAYLEINK-NPKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNNNLLLADQKS 964 Query: 953 AKVKQRIDYANLTGISVSSLSDSLFVLHVQR-ADNKQKGDVVLQSDHVIETLTK 1005 ++K + ++T +S+SS +D F +H++ ++ KGD + SDH+IE TK Sbjct: 965 GQIKSEVPLVDVTKVSMSSQNDGFFAVHLKEGSEAASKGDFLFSSDHLIEMATK 1018 >gi|4885503 myosin IA [Homo sapiens] Length = 1043 Score = 789 bits (2037), Expect = 0.0 Identities = 434/983 (44%), Positives = 624/983 (63%), Gaps = 31/983 (3%) Query: 46 VGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYR 105 VGV+D VLLE E+ ++NL+ R+ IYTYIG V++SVNPY+ L IY + + +Y+ Sbjct: 8 VGVEDLVLLEPLVEES-LLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQ 66 Query: 106 GVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPE 165 +FYE+ PH++A+A+ Y++LR RDQ ++I+GESG+GKTEA+K ++ + A C E Sbjct: 67 DYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGE 126 Query: 166 RGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKS 225 + +V+++LLQSNPVLEAFGNAKT+RN+NSSRFGKYMD++FDFKG+P+GG I +YLLEKS Sbjct: 127 QVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKS 186 Query: 226 RVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWK 285 R+V Q GERNFHIFYQLL G +E+ L+ L LER+ Y YL + ++V ++D S ++ Sbjct: 187 RLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYL-NHEVSRVDGMDDASSFR 245 Query: 286 VVRKALTVIDFTEDEVEDLLSIVASVLHLGNI----HFAANEESNAQVTTENQLKYLTRL 341 V+ A+ VI F+E+E+ +L + + VL LGN+ F A+ + + ++ + + Sbjct: 246 AVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIGEM 305 Query: 342 LSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL 401 + + + AL R + E++++ LN+ QA YARDALAK +YSR F W+V +IN S+ Sbjct: 306 VGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINESI 365 Query: 402 ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEY 461 E V+G+LDIYGFE+ + NSFEQF INYCNEKLQQ+FIE+TLK EQEEY Sbjct: 366 KVGIGEKKK-----VMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEY 420 Query: 462 EAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHP 521 + EGI W V YF+N IIC L+E +GI+++LDEECLRPG +D TFL KL H Sbjct: 421 KREGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHG 480 Query: 522 HFLTH--KLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKN 579 H+ + + A ++ ++G FR+ HYAG+VTY+VT F+DKNNDLLFR+L + M +++ Sbjct: 481 HYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQH 540 Query: 580 PIMSQCFDRS--ELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRF 637 P++ F + + KRP T QFK S+ L++ L SK P Y+RCIKPN+ +Q G+F Sbjct: 541 PLLRSLFPEGNPKQASLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRGQF 600 Query: 638 DEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVL 697 L+ Q +YLGLLEN+RVRRAG+A+R+ Y FL+RY+ L TWP W G ++GV + Sbjct: 601 SSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDREGVEKV 660 Query: 698 VRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRV 757 + L E G+TKIFIR PKTLF E+ +R Q LAT IQ +RG+ R + + Sbjct: 661 LGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHYQLM 720 Query: 758 KRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENA--------FFL 809 ++S I I SW+RG + ++ K K + I+ +RG+ R R + F Sbjct: 721 RKSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNYRKYFRSEAALTLADFIY 780 Query: 810 DHVRTSFLLNLRRQLPQ-NVLDTSWPTPP-PALREASELLRELCIKNMVWKYCRSISPEW 867 + FLL L+ LP NVLD +WP P L A++ L++L + ++ +SP+ Sbjct: 781 KSMVQKFLLGLKNNLPSTNVLDKTWPAAPYKCLSTANQELQQLFYQWKCKRFRDQLSPKQ 840 Query: 868 KQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQALGSE--PIQYAVPV 925 + L++K ASE+FKGKK +YPQSVP F +G + +P++ + G E P+ A V Sbjct: 841 VEILREKLCASELFKGKKASYPQSVPIPFCGDYIGL-QGNPKLQKLKGGEEGPVLMAEAV 899 Query: 926 VKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQR--IDYANLTGISVSSLSDSLFVLHVQR 983 K +R K SR LLLT V++ + K + + I N+ G+SV+SL D LF LH+ Sbjct: 900 KKVNRGNGKTSSRILLLTKGHVILTDTKKSQAKIVIGLDNVAGVSVTSLKDGLFSLHLSE 959 Query: 984 ADN-KQKGDVVLQSDHVIETLTK 1005 + KGD +L S+HVIE LTK Sbjct: 960 MSSVGSKGDFLLVSEHVIELLTK 982 >gi|194328685 myosin IB isoform 1 [Homo sapiens] Length = 1136 Score = 743 bits (1919), Expect = 0.0 Identities = 389/774 (50%), Positives = 518/774 (66%), Gaps = 22/774 (2%) Query: 46 VGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYR 105 +GV D VLLE E FI NL++RF + IYTYIG V++SVNPYR L IYS + +E YR Sbjct: 15 IGVGDMVLLEPLNEET-FINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYR 73 Query: 106 GVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPE 165 +FYE+ PH+FA++D YR+LR + +DQ ++I+GESGAGKTEA+K ++ + A C Sbjct: 74 NRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGA 133 Query: 166 RGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKS 225 V+++LLQSNPVLEAFGNAKT+RNDNSSRFGKYMD++FDFKG P+GG I +YLLEKS Sbjct: 134 EVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKS 193 Query: 226 RVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWK 285 RVV Q GERNFH+FYQLL G EE L +L LER+ Y YL AKV+ ++D ++++ Sbjct: 194 RVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYL-SLDSAKVNGVDDAANFR 252 Query: 286 VVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN----AQVTTENQLKYLTRL 341 VR A+ ++ F + E E +L++VA+VL LGNI F N +++ +N+LK + L Sbjct: 253 TVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICEL 312 Query: 342 LSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL 401 ++ S L A + R + AK E++ + LN+ QA YARDALAK +YSR F+WLV +IN S Sbjct: 313 TGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINES- 371 Query: 402 ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEY 461 +++ + V+G+LDIYGFE+F+ NSFEQF INYCNEKLQQ+FIELTLK EQEEY Sbjct: 372 ----IKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEY 427 Query: 462 EAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHP 521 E I W + YFNN IICDL+E GI+++LDEECLRPG TD TFLEKL H Sbjct: 428 IREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQ 487 Query: 522 HFLTH--KLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKN 579 HF + K + SL FR+ HYAG+V Y V GF+DKNNDLL+R+L + M + + Sbjct: 488 HFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASH 547 Query: 580 PIMSQCFDRSELS--DKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRF 637 ++ F + + KRP T +QFK S+ L++ LQ+K P Y+RCIKPND K F Sbjct: 548 ALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIF 607 Query: 638 DEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVL 697 +E L+ HQ++YLGLLEN+RVRRAG+A+R+ YE L+RYK LC +TWP W G + GV VL Sbjct: 608 NEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVL 667 Query: 698 VRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRV 757 L EEY GR+KIFIR P+TLF ED + R + LAT IQ +RG+ R FL + Sbjct: 668 FNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLM 727 Query: 758 KRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGF-------VLRHAPRCPE 804 K+S I I +W+R +++ + K +A I+ IRG+ L+H RC E Sbjct: 728 KKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKE 781 Score = 94.7 bits (234), Expect = 4e-19 Identities = 85/303 (28%), Positives = 143/303 (47%), Gaps = 34/303 (11%) Query: 733 RRQSLATKIQAAWRGFHWRQKFLRVKRSA------ICIQSWWRGTLGRRKA------AKR 780 R + T I A W G R++ R+K A I ++W G+ RR+ A+R Sbjct: 778 RCKEAVTTIAAYWHGTQARRELRRLKEEARNKHAIAVIWAYWLGSKARRELKRLKEEARR 837 Query: 781 K---------WAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTSFLLNLRRQLPQ-NVLD 830 K W +RR R F +A + F L + + L ++ ++P + +D Sbjct: 838 KHAVAVIWAYWLGLKVRREYRKFFRANAGK-KIYEFTLQRIVQKYFLEMKNKMPSLSPID 896 Query: 831 TSWPTPPPALREASELLRELCIKNMVW---KYCRSISPEWKQQLQQKAVASEIFKGKKDN 887 +WP+ P +++ +EL +W KY + + K ++K ASE+FK KK Sbjct: 897 KNWPSRPYLFLDSTH--KELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKAL 954 Query: 888 YPQSVPRLFISTRLGTDEISPRV--LQALGSEPIQYAVPVVKYDRKGYKPRSRQLLLTPN 945 YP SV + F L ++ +P+ L+ E I A V K +R K SR LLT N Sbjct: 955 YPSSVGQPFQGAYLEINK-NPKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNN 1013 Query: 946 AVVIVE--DAKVKQRIDYANLTGISVSSLSDSLFVLHVQR-ADNKQKGDVVLQSDHVIET 1002 +++ + ++K + ++T +S+SS +D F +H++ ++ KGD + SDH+IE Sbjct: 1014 NLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAVHLKEGSEAASKGDFLFSSDHLIEM 1073 Query: 1003 LTK 1005 TK Sbjct: 1074 ATK 1076 >gi|240120050 myosin IB isoform 1 [Homo sapiens] Length = 1136 Score = 743 bits (1919), Expect = 0.0 Identities = 389/774 (50%), Positives = 518/774 (66%), Gaps = 22/774 (2%) Query: 46 VGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYR 105 +GV D VLLE E FI NL++RF + IYTYIG V++SVNPYR L IYS + +E YR Sbjct: 15 IGVGDMVLLEPLNEET-FINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYR 73 Query: 106 GVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPE 165 +FYE+ PH+FA++D YR+LR + +DQ ++I+GESGAGKTEA+K ++ + A C Sbjct: 74 NRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGA 133 Query: 166 RGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKS 225 V+++LLQSNPVLEAFGNAKT+RNDNSSRFGKYMD++FDFKG P+GG I +YLLEKS Sbjct: 134 EVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKS 193 Query: 226 RVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWK 285 RVV Q GERNFH+FYQLL G EE L +L LER+ Y YL AKV+ ++D ++++ Sbjct: 194 RVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYL-SLDSAKVNGVDDAANFR 252 Query: 286 VVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN----AQVTTENQLKYLTRL 341 VR A+ ++ F + E E +L++VA+VL LGNI F N +++ +N+LK + L Sbjct: 253 TVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICEL 312 Query: 342 LSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL 401 ++ S L A + R + AK E++ + LN+ QA YARDALAK +YSR F+WLV +IN S Sbjct: 313 TGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINES- 371 Query: 402 ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEY 461 +++ + V+G+LDIYGFE+F+ NSFEQF INYCNEKLQQ+FIELTLK EQEEY Sbjct: 372 ----IKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEY 427 Query: 462 EAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHP 521 E I W + YFNN IICDL+E GI+++LDEECLRPG TD TFLEKL H Sbjct: 428 IREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQ 487 Query: 522 HFLTH--KLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKN 579 HF + K + SL FR+ HYAG+V Y V GF+DKNNDLL+R+L + M + + Sbjct: 488 HFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASH 547 Query: 580 PIMSQCFDRSELS--DKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRF 637 ++ F + + KRP T +QFK S+ L++ LQ+K P Y+RCIKPND K F Sbjct: 548 ALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIF 607 Query: 638 DEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVL 697 +E L+ HQ++YLGLLEN+RVRRAG+A+R+ YE L+RYK LC +TWP W G + GV VL Sbjct: 608 NEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVL 667 Query: 698 VRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRV 757 L EEY GR+KIFIR P+TLF ED + R + LAT IQ +RG+ R FL + Sbjct: 668 FNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLM 727 Query: 758 KRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGF-------VLRHAPRCPE 804 K+S I I +W+R +++ + K +A I+ IRG+ L+H RC E Sbjct: 728 KKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKE 781 Score = 94.7 bits (234), Expect = 4e-19 Identities = 85/303 (28%), Positives = 143/303 (47%), Gaps = 34/303 (11%) Query: 733 RRQSLATKIQAAWRGFHWRQKFLRVKRSA------ICIQSWWRGTLGRRKA------AKR 780 R + T I A W G R++ R+K A I ++W G+ RR+ A+R Sbjct: 778 RCKEAVTTIAAYWHGTQARRELRRLKEEARNKHAIAVIWAYWLGSKARRELKRLKEEARR 837 Query: 781 K---------WAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTSFLLNLRRQLPQ-NVLD 830 K W +RR R F +A + F L + + L ++ ++P + +D Sbjct: 838 KHAVAVIWAYWLGLKVRREYRKFFRANAGK-KIYEFTLQRIVQKYFLEMKNKMPSLSPID 896 Query: 831 TSWPTPPPALREASELLRELCIKNMVW---KYCRSISPEWKQQLQQKAVASEIFKGKKDN 887 +WP+ P +++ +EL +W KY + + K ++K ASE+FK KK Sbjct: 897 KNWPSRPYLFLDSTH--KELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKAL 954 Query: 888 YPQSVPRLFISTRLGTDEISPRV--LQALGSEPIQYAVPVVKYDRKGYKPRSRQLLLTPN 945 YP SV + F L ++ +P+ L+ E I A V K +R K SR LLT N Sbjct: 955 YPSSVGQPFQGAYLEINK-NPKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNN 1013 Query: 946 AVVIVE--DAKVKQRIDYANLTGISVSSLSDSLFVLHVQR-ADNKQKGDVVLQSDHVIET 1002 +++ + ++K + ++T +S+SS +D F +H++ ++ KGD + SDH+IE Sbjct: 1014 NLLLADQKSGQIKSEVPLVDVTKVSMSSQNDGFFAVHLKEGSEAASKGDFLFSSDHLIEM 1073 Query: 1003 LTK 1005 TK Sbjct: 1074 ATK 1076 >gi|51100974 myosin ID [Homo sapiens] Length = 1006 Score = 697 bits (1800), Expect = 0.0 Identities = 415/961 (43%), Positives = 578/961 (60%), Gaps = 65/961 (6%) Query: 47 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 106 G DFVL++ S F+ NLR RF + IYT+IG V+VSVNPY+ L IY R +E+Y+G Sbjct: 10 GKADFVLMDT-VSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKG 68 Query: 107 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 166 YE PPHLFA+AD Y+A++ +D ++ISGESGAGKTEA+K ++Q+ A +R Sbjct: 69 RELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQR 128 Query: 167 GGA--VRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEK 224 V++ LL+SN VLEAFGNAKT RNDNSSRFGKYMD+ FDFKG P+GGHI +YLLEK Sbjct: 129 AEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188 Query: 225 SRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDW 284 SRV+ Q GER+FH FYQLL+GG E+ LR L L+++ SY Y+ G K SSIND +++ Sbjct: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLK-SSINDAAEF 247 Query: 285 KVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQLKYLTRLLSV 344 +VV A+ VI F +E++ + I+A++LHLGN+ F + ++ + + + LLS Sbjct: 248 RVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPL-IENGKVVSIIAELLST 306 Query: 345 EGSTLREALTHRKIIAKGEELLSPLNLEQ-AAYARDALAKAVYSRTFTWLVGKINRSLAS 403 + + +AL +R + A G +++ + EQ A+Y RDA AKA+Y R F W+V +IN + Sbjct: 307 KTDMVEKALLYRTV-ATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEV 365 Query: 404 KDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEA 463 K+ ++ TV+G+LDIYGFE+F +NSFEQFCINYCNEKLQQLFI+L LK EQEEY+ Sbjct: 366 KNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQR 425 Query: 464 EGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPHF 523 EGI W+ + YFNN+II DLVE++ KGII+ILD+ C+ G+ TD FLE L + H HF Sbjct: 426 EGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAHF 485 Query: 524 LTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMS 583 + KL R +FR+ HYAG+V YSV GF+DKN D LF++ K M +S NP++ Sbjct: 486 SSRKLCASDKILEFDR-DFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLK 544 Query: 584 QCFDRSELSDK---KRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEV 640 + +LS KRP T AT FK S++ LV+ L SKEP YVRCIKPND K P FD+ Sbjct: 545 NMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDE 604 Query: 641 LIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAV--LV 698 RHQV+YLGLLEN+RVRRAGFA+R+ YE FL RYK + TWP P D AV L+ Sbjct: 605 RCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNH-DLPSDKEAVKKLI 663 Query: 699 RHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRVK 758 G++ ++ G+TKIFIR P+TLF E E+R Q L Sbjct: 664 ERCGFQ-DDVAYGKTKIFIRTPRTLFTLE---ELRAQMLI-------------------- 699 Query: 759 RSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTSFLL 818 R + +Q WRGTL R + KR AA TI R R + ++ ++ + R + Sbjct: 700 RIVLFLQKVWRGTLARMRY-KRTKAALTIIRYYRRYKVK--------SYIHEVARRFHGV 750 Query: 819 NLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISPEWKQQLQQKAVAS 878 R ++V WP+PP LR E L+ + + + +SI Q++ K A Sbjct: 751 KTMRDYGKHV---KWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAV 807 Query: 879 EIFKGKKDN--YPQSVPRLFISTRLGTDEISPRVLQALGS-------EPIQYAVPVVKYD 929 E+ KG++ + ++ +++++ T + S + + ++ V K + Sbjct: 808 EMLKGQRADLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVN 867 Query: 930 RKGYKPRSRQLLLTPNAVVIVEDA---KVKQRIDYANLTGISVSSLSDSLFVLHVQRADN 986 R K R + +T + ++ KV + I NLTG+SVS+ D L V H + DN Sbjct: 868 RFS-KVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTK--DN 924 Query: 987 K 987 K Sbjct: 925 K 925 >gi|239582755 myosin IG [Homo sapiens] Length = 1018 Score = 658 bits (1698), Expect = 0.0 Identities = 409/970 (42%), Positives = 555/970 (57%), Gaps = 71/970 (7%) Query: 47 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 106 G DFVLL+ T E F+ NL+ RF + IYTYIG VLVSVNPY++L +Y + + RY+G Sbjct: 10 GKPDFVLLDQVTMED-FMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIARYQG 68 Query: 107 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 166 YE PPHL+AVA+ Y+A++ RD ++ISGESGAGKTEA+K ++Q+ A +R Sbjct: 69 RELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQR 128 Query: 167 GGA--VRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEK 224 V+D LL+S VLEAFGNA+T RN NSSRFGKYMD+ FDFKG P+GGHI SYLLEK Sbjct: 129 AEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEK 188 Query: 225 SRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSIN----D 280 SRV+ Q+ GERNFH FYQLL G E++ L L LERNP Y + +G ++ + D Sbjct: 189 SRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALDSD 248 Query: 281 KSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQ-----VTTENQL 335 + + V +A+ VI F+ +EVE + I+A++LHLGNI F EE Q V E + Sbjct: 249 EQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLAVAEEALV 308 Query: 336 KYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLE-QAAYARDALAKAVYSRTFTWLV 394 ++ L + + +L R + + G EL+ + +A+YARDA AKAVY R F W+V Sbjct: 309 DHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQRLFEWVV 368 Query: 395 GKINRSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTL 454 +IN + + + TV+G+LDIYGFEVF NSFEQFCINYCNEKLQQLFI+L L Sbjct: 369 NRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQLIL 428 Query: 455 KSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLE 514 K EQEEYE EGI W+ V+YFNN I DLVE +GI+++LDE C G TD FL+ L+ Sbjct: 429 KQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDRIFLQTLD 488 Query: 515 DTVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETM 574 +HH H+ + +L GR +FR+ HYAG+VTYSV GF+DKN D LF++ K + Sbjct: 489 MHHRHHLHYTSRQLCPTDKTMEFGR-DFRIKHYAGDVTYSVEGFIDKNRDFLFQDFKRLL 547 Query: 575 CSSKNPIMSQCF-----DRSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPN 629 +S +P + + D +E++ KRP T T FK S++ LVE L SKEP YVRCIKPN Sbjct: 548 YNSTDPTLRAMWPDGQQDITEVT--KRPLTAGTLFKNSMVALVENLASKEPFYVRCIKPN 605 Query: 630 DAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWA-G 688 + K G+ DE RHQV YLGLLEN+RVRRAGFA R+ Y FL RYK C TWP G Sbjct: 606 EDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWPNHLLG 665 Query: 689 RPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGF 748 + V+ L+ G + + G +K+FIR P+TL E QS A I Sbjct: 666 SDKAAVSALLEQHGLQGD-VAFGHSKLFIRSPRTLVTLE-------QSRARLIPII---- 713 Query: 749 HWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFF 808 + +Q WRGTL R + +R A TI R R RH R Sbjct: 714 ------------VLLLQKAWRGTLARWRC-RRLRAIYTIMRWFR----RHKVRA-----H 751 Query: 809 LDHVRTSFLLNLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISPEWK 868 L ++ F RQ P D WP PP L+ + L + + ++I P Sbjct: 752 LAELQRRF--QAARQPPLYGRDLVWPLPPAVLQPFQDTCHALFCRWRARQLVKNIPPSDM 809 Query: 869 QQLQQKAVASEIFKGKKDNY--PQSVPRLFISTRLGTDEISPRVLQAL-------GSEPI 919 Q++ K A +G + ++ ++ R ++S+ S Q L G + Sbjct: 810 PQIKAKVAAMGALQGLRQDWGCRRAWARDYLSSATDNPTASSLFAQRLKTLQDKDGFGAV 869 Query: 920 QYAVPVVKYDRKGYKPRSRQLLLTPNAVVIVE---DAKVKQRIDYANLTGISVSSLSDSL 976 ++ V K +R +K R+R LLLT + ++ +V + + +TG+SV+S D L Sbjct: 870 LFSSHVRKVNR-FHKIRNRALLLTDQHLYKLDPDRQYRVMRAVPLEAVTGLSVTSGGDQL 928 Query: 977 FVLHVQRADN 986 VLH + D+ Sbjct: 929 VVLHARGQDD 938 >gi|27544941 myosin IF [Homo sapiens] Length = 1098 Score = 612 bits (1579), Expect = e-175 Identities = 334/726 (46%), Positives = 460/726 (63%), Gaps = 34/726 (4%) Query: 47 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 106 GV D VLL T E A NLR+RF ++ I+TYIG VL+SVNP++ + ++ + ++ Y+G Sbjct: 18 GVDDMVLLPQIT-EDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQG 76 Query: 107 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 166 + YE PPH++A+ D +YR + + +Q V+ISGESGAGKT A K ++ + ++ E+ Sbjct: 77 AAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEK 136 Query: 167 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSR 226 V+D +LQSNP+LEAFGNAKT+RN+NSSRFGKY ++QF G P GG I ++LLEKSR Sbjct: 137 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSR 196 Query: 227 VVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKV 286 VV QN ERNFHI+YQLLEG +E + LGL P Y YL + +V +D+SD+ Sbjct: 197 VVMQNENERNFHIYYQLLEGASQEQRQNLGL-MTPDYYYYLNQSDTYQVDGTDDRSDFGE 255 Query: 287 VRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN-AQVTTENQLKYLTRLLSVE 345 A+ VI + +L +VA +LHLGNI F E+ N A+V + + L + LL ++ Sbjct: 256 TLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFC--EDGNYARVESVDLLAFPAYLLGID 313 Query: 346 GSTLREALTHRKIIA----KGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL 401 L+E LT RK+ + + E + LN+EQAAY RDALAK +Y+R F +LV INR++ Sbjct: 314 SGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAM 373 Query: 402 ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEY 461 E +G+LDIYGFE+FQ N FEQFCIN+ NEKLQQ+FIELTLK+EQEEY Sbjct: 374 QKPQEEYS-------IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEY 426 Query: 462 EAEGIAWEPVQYFNNKIICDLVEEKFK--GIISILDEECL---RPGEATDLTFLEKLEDT 516 EGI W P+QYFNNK++CDL+E K GI+S+LD+ C G D T L+KL+ Sbjct: 427 VQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAA 486 Query: 517 VKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCS 576 V H HF S G F + HYAG+V+Y V+GF ++N D+LF +L E M + Sbjct: 487 VGTHEHF-----------NSWSAG-FVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQT 534 Query: 577 SKNPIMSQCFDRSELSDKK-RPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPG 635 S+ + F DKK RP T ++ K LV L P Y+RCIKPN+ K+P Sbjct: 535 SEQAFLRMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPR 594 Query: 636 RFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVA 695 ++E ++HQV+YLGL EN+RVRRAGFAYRR++ FLQRY L PETWP W G + GV Sbjct: 595 DWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQ 654 Query: 696 VLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFL 755 L+R + +P++Y+MG TK+F++ P++LF E+ E + A IQ AWR +K+ Sbjct: 655 HLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYE 714 Query: 756 RVKRSA 761 ++ A Sbjct: 715 EMREEA 720 Score = 68.2 bits (165), Expect = 4e-11 Identities = 46/148 (31%), Positives = 73/148 (49%), Gaps = 22/148 (14%) Query: 859 YCRSISPEWKQQL------QQKAVASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQ 912 + R+I W++ + + + AS I KK+ S+ R F+ LG +E P + Q Sbjct: 696 FARTIQKAWRRHVAVRKYEEMREEASNILLNKKERRRNSINRNFVGDYLGLEE-RPELRQ 754 Query: 913 ALGS-EPIQYAVPVVKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQ-------------R 958 LG E + +A V KYDR+ +KP R L+LTP V ++ KVK+ + Sbjct: 755 FLGKRERVDFADSVTKYDRR-FKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKK 813 Query: 959 IDYANLTGISVSSLSDSLFVLHVQRADN 986 +D L G+S+S+ D F+L AD+ Sbjct: 814 VDIQALRGVSLSTRQDDFFILQEDAADS 841 >gi|55956916 myosin IE [Homo sapiens] Length = 1108 Score = 608 bits (1569), Expect = e-174 Identities = 331/726 (45%), Positives = 467/726 (64%), Gaps = 34/726 (4%) Query: 47 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 106 GV D VLL T E + +ENL++R+ ++ I+TYIG VL+SVNP++ + + + +E Y+G Sbjct: 20 GVDDMVLLSKIT-ENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQG 78 Query: 107 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 166 + YE PPH++A+AD +YR + +R +Q V+ISGESGAGKT A K ++ + + + Sbjct: 79 AAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTK 138 Query: 167 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSR 226 V+D +LQSNP+LEAFGNAKT+RN+NSSRFGKY ++QF G P GG I ++LLEKSR Sbjct: 139 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSR 198 Query: 227 VVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKV 286 VV +N GER+FHIFYQL+EG E LG+ + Y YL KV I+D+ +++ Sbjct: 199 VVMRNPGERSFHIFYQLIEGASAEQKHSLGI-TSMDYYYYLSLSGSYKVDDIDDRREFQE 257 Query: 287 VRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN-AQVTTENQLKYLTRLLSVE 345 A+ VI +E +L IVA +LHLGNI F E N A V +E L + LL + Sbjct: 258 TLHAMNVIGIFAEEQTLVLQIVAGILHLGNISF--KEVGNYAAVESEEFLAFPAYLLGIN 315 Query: 346 GSTLREALTHRKIIA----KGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL 401 L+E LT R++ + K E + LN+EQA Y RDALAKA+++R F +LV IN+++ Sbjct: 316 QDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAM 375 Query: 402 ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEY 461 KD E + +G+LDIYGFE+FQ N FEQFCIN+ NEKLQQ+FIELTLK+EQEEY Sbjct: 376 -EKDHEEYN------IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEY 428 Query: 462 EAEGIAWEPVQYFNNKIICDLVEEKFK--GIISILDEECL---RPGEATDLTFLEKLEDT 516 EGI W P++YFNNKI+CDL+E K GI+SILD+ C GE D T L+KL+ Sbjct: 429 VQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQ 488 Query: 517 VKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCS 576 + H HF S +G F + HYAG+V+Y + GF ++N D+LF +L E M S Sbjct: 489 IGSHEHF-----------NSWNQG-FIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQS 536 Query: 577 SKNPIMSQCFDRSELSDKK-RPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPG 635 S+ P + F + +DKK RP T ++ K LV L P Y+RCIKPN+ K+P Sbjct: 537 SELPFIKSLFPENLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPR 596 Query: 636 RFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVA 695 ++E ++HQV+YLGL EN+RVRRAG+AYRR ++ FLQRY L TWP+W G + GV Sbjct: 597 DWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVL 656 Query: 696 VLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFL 755 L++ + +++++GR+K+FI+ P++LF E+ E + A IQ +WR F R+K++ Sbjct: 657 HLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYV 716 Query: 756 RVKRSA 761 +++ A Sbjct: 717 QMREEA 722 Score = 69.3 bits (168), Expect = 2e-11 Identities = 47/148 (31%), Positives = 74/148 (50%), Gaps = 22/148 (14%) Query: 859 YCRSISPEW------KQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQ 912 Y R I W K+ +Q + AS++ KK+ S+ R FI +G +E P + Q Sbjct: 698 YARVIQKSWRKFVARKKYVQMREEASDLLLNKKERRRNSINRNFIGDYIGMEE-HPELQQ 756 Query: 913 ALGS-EPIQYAVPVVKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQ-------------R 958 +G E I +A V KYDR+ +K R LLLTP + ++ KVKQ + Sbjct: 757 FVGKREKIDFADTVTKYDRR-FKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRK 815 Query: 959 IDYANLTGISVSSLSDSLFVLHVQRADN 986 I+ + +S+S++ D +F+LH Q D+ Sbjct: 816 IEIERILSVSLSTMQDDIFILHEQEYDS 843 >gi|122937512 myosin VIIB [Homo sapiens] Length = 2116 Score = 514 bits (1324), Expect = e-145 Identities = 290/759 (38%), Positives = 437/759 (57%), Gaps = 50/759 (6%) Query: 47 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 106 GV D + L + +EA + NL R++++ IYTY G +LV+VNP++ L +Y+ + ++ Y Sbjct: 66 GVDDMIRLGDL-NEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYS 124 Query: 107 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 166 E+PPH+FA+A+ Y +++ +RDQ +ISGESGAGKTE TK +LQF A + Sbjct: 125 RHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLA---TISGQ 181 Query: 167 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSR 226 + ++L++NP+LEAFGNAKT+RNDNSSRFGKY+D+ F+ G G I +LLEKSR Sbjct: 182 HSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSR 241 Query: 227 VVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKV 286 V Q ERN+HIFY +L G E + L L P Y YL G C +ND D+ Sbjct: 242 VCRQAPEERNYHIFYCMLMGVSAEDKQLLSL-GTPSEYHYLTMGNCTSCEGLNDAKDYAH 300 Query: 287 VRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN---AQVTTENQLKYLTRLLS 343 +R A+ ++ F++ E D++ ++A++LHLGN+ F A+ N + V + +LL Sbjct: 301 IRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLE 360 Query: 344 VEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLAS 403 V+ LR+ L I+ +GE + LN+ QAA RDA K +Y F W+V KIN ++ + Sbjct: 361 VQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFT 420 Query: 404 KDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEA 463 + P +GLLDI+GFE F++NSFEQ CIN+ NE LQQ F++ EQEEY + Sbjct: 421 PPAQDPK-NVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRS 479 Query: 464 EGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPHF 523 E I+W+ + Y +N+ DL+ K IIS+LDEE P + TDLT L+KL ++ F Sbjct: 480 ENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFP-QGTDLTMLQKLNSVHANNKAF 538 Query: 524 LTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMS 583 L K++ F + H+AGEV Y GFL+KN D+L ++ + SSKN + Sbjct: 539 L--------QPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLR 590 Query: 584 QCFDRSELSDK----------------------KRPETVATQFKMSLLQLVEILQSKEPA 621 + F+ K KRP T+ +QFK SL QL++IL + +P Sbjct: 591 EIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPY 650 Query: 622 YVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPE 681 ++RCIKPN+ K+P FD L Q++Y G++E + +R++GF R +E F QR+ L P Sbjct: 651 FIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPN 710 Query: 682 TWPTWAGRPQDGVAVLVRHLGYKPE-EYKMGRTKIFIRFPKTLFATEDALEVRRQSL--- 737 + + + + + + ++K G+TKIF+R + + LEV+R + Sbjct: 711 AMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQ-----DTLLEVQRSQVLDR 765 Query: 738 -ATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRR 775 A IQ RG+ +R++FLR +R+A+ +Q+WWRG RR Sbjct: 766 AALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRR 804 >gi|189083802 myosin VIIA isoform 2 [Homo sapiens] Length = 2175 Score = 505 bits (1300), Expect = e-142 Identities = 296/743 (39%), Positives = 429/743 (57%), Gaps = 47/743 (6%) Query: 47 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 106 GV+D + L + +EA + NL R+R++LIYTY G +LV+VNPY+ L IYS +H+ +Y Sbjct: 66 GVEDMIRLGDL-NEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTN 124 Query: 107 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 166 E+PPH+FA+AD Y ++ RDQ +ISGESGAGKTE+TK +LQF A + Sbjct: 125 KKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA---AISGQ 181 Query: 167 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSR 226 + ++L++ P+LEAFGNAKT+RNDNSSRFGKY+D+ F+ +GA G I YLLEKSR Sbjct: 182 HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSR 241 Query: 227 VVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKV 286 V Q ERN+H+FY +LEG E+ ++LGL + Y YL G C D ++ Sbjct: 242 VCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQ-ASDYNYLAMGNCITCEGRVDSQEYAN 300 Query: 287 VRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN---AQVTTENQLKYLTRLLS 343 +R A+ V+ FT+ E ++ ++A++LHLGN+ + A N +V L LL Sbjct: 301 IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLE 360 Query: 344 VEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL-- 401 V L LT R +I +GE + +PL+ EQA RDA K +Y R F W+V KIN ++ Sbjct: 361 VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK 420 Query: 402 -ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEE 460 S+DV++ S +GLLDI+GFE F NSFEQ CIN+ NE LQQ F+ K EQEE Sbjct: 421 PPSQDVKN----SRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEE 476 Query: 461 YEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHH 520 Y+ E I W +++ +N+ D++ K IIS++DEE P + TD T L KL K + Sbjct: 477 YDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP-KGTDTTMLHKLNSQHKLN 535 Query: 521 PHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNP 580 +++ K + +F + H+AG V Y GFL+KN D L ++ + + SS+N Sbjct: 536 ANYIPPKNNHET--------QFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNK 587 Query: 581 IMSQCFDRS---ELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRF 637 + Q F +KR T+++QFK SL L+ L + +P +VRCIKPN+ K+P F Sbjct: 588 FIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLF 647 Query: 638 DEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGV--- 694 D L Q++Y G++E +R+RRAG+ R + F++RY+ L P P + G Sbjct: 648 DRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQR 707 Query: 695 ---AVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATK----IQAAWRG 747 AVL H +++++G+TKIF++ + LEV R T +Q RG Sbjct: 708 MAEAVLGTH-----DDWQIGKTKIFLKDHHDML-----LEVERDKAITDRVILLQKVIRG 757 Query: 748 FHWRQKFLRVKRSAICIQSWWRG 770 F R FL++K +A IQ WRG Sbjct: 758 FKDRSNFLKLKNAATLIQRHWRG 780 >gi|189083800 myosin VIIA isoform 3 [Homo sapiens] Length = 1204 Score = 505 bits (1300), Expect = e-142 Identities = 296/743 (39%), Positives = 429/743 (57%), Gaps = 47/743 (6%) Query: 47 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 106 GV+D + L + +EA + NL R+R++LIYTY G +LV+VNPY+ L IYS +H+ +Y Sbjct: 66 GVEDMIRLGDL-NEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTN 124 Query: 107 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 166 E+PPH+FA+AD Y ++ RDQ +ISGESGAGKTE+TK +LQF A + Sbjct: 125 KKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA---AISGQ 181 Query: 167 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSR 226 + ++L++ P+LEAFGNAKT+RNDNSSRFGKY+D+ F+ +GA G I YLLEKSR Sbjct: 182 HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSR 241 Query: 227 VVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKV 286 V Q ERN+H+FY +LEG E+ ++LGL + Y YL G C D ++ Sbjct: 242 VCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQ-ASDYNYLAMGNCITCEGRVDSQEYAN 300 Query: 287 VRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN---AQVTTENQLKYLTRLLS 343 +R A+ V+ FT+ E ++ ++A++LHLGN+ + A N +V L LL Sbjct: 301 IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLE 360 Query: 344 VEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL-- 401 V L LT R +I +GE + +PL+ EQA RDA K +Y R F W+V KIN ++ Sbjct: 361 VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK 420 Query: 402 -ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEE 460 S+DV++ S +GLLDI+GFE F NSFEQ CIN+ NE LQQ F+ K EQEE Sbjct: 421 PPSQDVKN----SRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEE 476 Query: 461 YEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHH 520 Y+ E I W +++ +N+ D++ K IIS++DEE P + TD T L KL K + Sbjct: 477 YDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP-KGTDTTMLHKLNSQHKLN 535 Query: 521 PHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNP 580 +++ K + +F + H+AG V Y GFL+KN D L ++ + + SS+N Sbjct: 536 ANYIPPKNNHET--------QFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNK 587 Query: 581 IMSQCFDRS---ELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRF 637 + Q F +KR T+++QFK SL L+ L + +P +VRCIKPN+ K+P F Sbjct: 588 FIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLF 647 Query: 638 DEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGV--- 694 D L Q++Y G++E +R+RRAG+ R + F++RY+ L P P + G Sbjct: 648 DRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQR 707 Query: 695 ---AVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATK----IQAAWRG 747 AVL H +++++G+TKIF++ + LEV R T +Q RG Sbjct: 708 MAEAVLGTH-----DDWQIGKTKIFLKDHHDML-----LEVERDKAITDRVILLQKVIRG 757 Query: 748 FHWRQKFLRVKRSAICIQSWWRG 770 F R FL++K +A IQ WRG Sbjct: 758 FKDRSNFLKLKNAATLIQRHWRG 780 >gi|189083798 myosin VIIA isoform 1 [Homo sapiens] Length = 2215 Score = 505 bits (1300), Expect = e-142 Identities = 296/743 (39%), Positives = 429/743 (57%), Gaps = 47/743 (6%) Query: 47 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 106 GV+D + L + +EA + NL R+R++LIYTY G +LV+VNPY+ L IYS +H+ +Y Sbjct: 66 GVEDMIRLGDL-NEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTN 124 Query: 107 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 166 E+PPH+FA+AD Y ++ RDQ +ISGESGAGKTE+TK +LQF A + Sbjct: 125 KKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLA---AISGQ 181 Query: 167 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSR 226 + ++L++ P+LEAFGNAKT+RNDNSSRFGKY+D+ F+ +GA G I YLLEKSR Sbjct: 182 HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSR 241 Query: 227 VVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKV 286 V Q ERN+H+FY +LEG E+ ++LGL + Y YL G C D ++ Sbjct: 242 VCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQ-ASDYNYLAMGNCITCEGRVDSQEYAN 300 Query: 287 VRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN---AQVTTENQLKYLTRLLS 343 +R A+ V+ FT+ E ++ ++A++LHLGN+ + A N +V L LL Sbjct: 301 IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLE 360 Query: 344 VEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL-- 401 V L LT R +I +GE + +PL+ EQA RDA K +Y R F W+V KIN ++ Sbjct: 361 VNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYK 420 Query: 402 -ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEE 460 S+DV++ S +GLLDI+GFE F NSFEQ CIN+ NE LQQ F+ K EQEE Sbjct: 421 PPSQDVKN----SRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEE 476 Query: 461 YEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHH 520 Y+ E I W +++ +N+ D++ K IIS++DEE P + TD T L KL K + Sbjct: 477 YDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP-KGTDTTMLHKLNSQHKLN 535 Query: 521 PHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNP 580 +++ K + +F + H+AG V Y GFL+KN D L ++ + + SS+N Sbjct: 536 ANYIPPKNNHET--------QFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNK 587 Query: 581 IMSQCFDRS---ELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRF 637 + Q F +KR T+++QFK SL L+ L + +P +VRCIKPN+ K+P F Sbjct: 588 FIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLF 647 Query: 638 DEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGV--- 694 D L Q++Y G++E +R+RRAG+ R + F++RY+ L P P + G Sbjct: 648 DRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQR 707 Query: 695 ---AVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATK----IQAAWRG 747 AVL H +++++G+TKIF++ + LEV R T +Q RG Sbjct: 708 MAEAVLGTH-----DDWQIGKTKIFLKDHHDML-----LEVERDKAITDRVILLQKVIRG 757 Query: 748 FHWRQKFLRVKRSAICIQSWWRG 770 F R FL++K +A IQ WRG Sbjct: 758 FKDRSNFLKLKNAATLIQRHWRG 780 >gi|154354979 myosin X [Homo sapiens] Length = 2058 Score = 483 bits (1243), Expect = e-136 Identities = 300/788 (38%), Positives = 447/788 (56%), Gaps = 57/788 (7%) Query: 38 SALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQ-IY 96 +A+ + GV D L + + NL +R++ N IYTYIG +L SVNPY+ + +Y Sbjct: 55 TAMHPTNEEGVDDMASLTELHG-GSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLY 113 Query: 97 SRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQF 156 ME+Y E+PPH+FA+A+ YR L +Q ++ISGESGAGKTE+TK +L+F Sbjct: 114 EPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKF 173 Query: 157 YAETCPAP------ERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKG 210 + E+ V +L+S+P++EAFGNAKT+ N+NSSRFGK++ + KG Sbjct: 174 LSVISQQSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKG 233 Query: 211 APVGGHILSYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKG 270 GG I+ YLLEK+RVV QN GERN+HIFY LL G E E L P++Y YL + Sbjct: 234 NIQGGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLS-TPENYHYLNQS 292 Query: 271 QCAKVSSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVT 330 C + +I+D+ ++ V A+ V+ F+++EV ++ ++A +LHLGNI F AQV+ Sbjct: 293 GCVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFIT--AGGAQVS 350 Query: 331 TENQLKYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTF 390 + L LL ++ + L +ALT R + +GEE+L+PLN++QA +RD+LA A+Y+ F Sbjct: 351 FKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCF 410 Query: 391 TWLVGKIN-RSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLF 449 W++ KIN R ++D +S +G+LDI+GFE F+ N FEQF INY NEKLQ+ F Sbjct: 411 EWVIKKINSRIKGNEDFKS--------IGILDIFGFENFEVNHFEQFNINYANEKLQEYF 462 Query: 450 IELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTF 509 + EQ EY EG+ WE + + +N DL+E+K G++++++EE P +ATD T Sbjct: 463 NKHIFSLEQLEYSREGLVWEDIDWIDNGECLDLIEKKL-GLLALINEESHFP-QATDSTL 520 Query: 510 LEKLEDTVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRN 569 LEKL H H H R + F + HYAGEV Y V G L+KN D + Sbjct: 521 LEKL-----HSQHANNHFYVKPR----VAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDD 571 Query: 570 LKETMCSSKNPIMSQCF---------DRSELSDKKRPETVATQFKMSLLQLVEILQSKEP 620 L + S+ + F D + K R TV++QFK SL L+ L S P Sbjct: 572 LLNLLRESRFDFIYDLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNP 631 Query: 621 AYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCP 680 +VRCIKPN K P +FD+ ++ +Q++Y G+LE +R+R+AG+A RR ++ F +RYK L Sbjct: 632 FFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMR 691 Query: 681 ETWPTWAGRPQD---GVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQS- 736 P+D L++ E+++G+TK+F+R + E LE RR+ Sbjct: 692 N-----LALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLR-----ESLEQKLEKRREEE 741 Query: 737 ---LATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRG 793 A I+A GF R+++ +V + IQ +R L RR+ K AA ++ +RG Sbjct: 742 VSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRG 801 Query: 794 FVLRHAPR 801 + R R Sbjct: 802 QIARRVYR 809 >gi|153945715 myosin VC [Homo sapiens] Length = 1742 Score = 480 bits (1236), Expect = e-135 Identities = 291/781 (37%), Positives = 438/781 (56%), Gaps = 52/781 (6%) Query: 46 VGVQDFVLLENFTSEAAFIENLRRRFREN-LIYTYIGPVLVSVNPYRDLQIYSRQHMERY 104 VG D L ++ E A + NLR RF E+ LIYTY G +LV++NPY+ L IY + Y Sbjct: 67 VGENDLTAL-SYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAY 125 Query: 105 RGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAP 164 G + ++ PH+FAVA+ Y+ + R+Q++++SGESGAGKT + + ++++A T Sbjct: 126 SGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFA-TVSKS 184 Query: 165 ERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEK 224 V D++L SNP+ EA GNAKT RNDNSSRFGKY ++ FD + +G ++ +YLLEK Sbjct: 185 GSNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEK 244 Query: 225 SRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDW 284 SRVV Q+ ERN+HIFYQL ++ + L L + + + Y G + +ND+++ Sbjct: 245 SRVVFQSENERNYHIFYQLCASAQQSEFKHLKL-GSAEEFNYTRMGGNTVIEGVNDRAEM 303 Query: 285 KVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAA--NEESNAQVTTENQLKYLTRLL 342 +K T++ F ED D+ I+A++LHLGN+ A NE S+ ++ LK LL Sbjct: 304 VETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVS-EDDSHLKVFCELL 362 Query: 343 SVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLA 402 +E + + L +RKI+ E ++ P+ QA ARDALAK +Y+ F ++V +IN++L Sbjct: 363 GLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQ 422 Query: 403 SKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYE 462 S + T +G+LDIYGFE F NSFEQFCINY NEKLQQ F K EQEEY Sbjct: 423 F------SGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYM 476 Query: 463 AEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKL-EDTVKHHP 521 E I W + +++N+ + DL+E K GI+ +LDEECL P TD +L+KL + V +P Sbjct: 477 KEDIPWTLIDFYDNQPVIDLIEAKM-GILELLDEECLLP-HGTDENWLQKLYNNFVNRNP 534 Query: 522 HFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPI 581 F + + F + H+A +V Y GFL+KN D ++ L E + +SK + Sbjct: 535 LF---------EKPRMSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHL 585 Query: 582 MSQCFDRS--------------------ELSDKKRPETVATQFKMSLLQLVEILQSKEPA 621 + F + + + K TV ++F+ SL L+E L + P Sbjct: 586 CANFFQENPTPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPH 645 Query: 622 YVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPE 681 YVRCIKPND K P FD I Q++ G+LE +R+ + R Y F RY L + Sbjct: 646 YVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTK 705 Query: 682 TWPTWAGRPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKI 741 +++ + ++ V++ L +Y+ G+TKIF R + + + L+ RQS + Sbjct: 706 QELSFSDK-KEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQS-CVMV 763 Query: 742 QAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRK-----AAKRKWAAQTIRRLIRGFVL 796 Q RG+ R+KFLR +R+A+ IQ ++RG RK A K WAA I++ RG+++ Sbjct: 764 QKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLV 823 Query: 797 R 797 R Sbjct: 824 R 824 >gi|118402590 myosin XV [Homo sapiens] Length = 3530 Score = 467 bits (1202), Expect = e-131 Identities = 275/772 (35%), Positives = 449/772 (58%), Gaps = 50/772 (6%) Query: 47 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 106 GV+D LE+ E + NL+ RF NLIYTYIG +LVSVNPY+ IY + +++Y G Sbjct: 1223 GVEDMTQLEDL-QETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNG 1281 Query: 107 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 166 + E PPHLFAVA+ + + +++Q ++ISGESG+GKTEATK +L++ A +R Sbjct: 1282 RALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLA--AMNQKR 1339 Query: 167 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILS-YLLEKS 225 + ++L++ P+LE+FGNAKT+RNDNSSRFGK++++ + G + G I S YLLEKS Sbjct: 1340 EVMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEIFLE--GGVISGAITSQYLLEKS 1397 Query: 226 RVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWK 285 R+V Q ERN+HIFY+LL G + + L+ ++Y YL +G +++ +D D++ Sbjct: 1398 RIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQ-EAETYYYLNQGGNCEIAGKSDADDFR 1456 Query: 286 VVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANE---ESNAQVTTENQLKYLTRLL 342 + A+ V+ F+ ++ + + I+AS+LHLGN++F E + A V + +++ + LL Sbjct: 1457 RLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELL 1516 Query: 343 SVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLA 402 + L++A+T + E++ +PL +E A ARDA+AK +Y+ F+WL+ ++N ++ Sbjct: 1517 QISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALVS 1576 Query: 403 SKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYE 462 + + T + +LDIYGFE NSFEQ CINY NE LQ LF ++ + EQEEY Sbjct: 1577 PR-------QDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYI 1629 Query: 463 AEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPH 522 E I W+ + + +N+ +L+ K GI+ ILD++C P +ATD TFL+K H H Sbjct: 1630 REQIDWQEITFADNQPCINLISLKPYGILRILDDQCCFP-QATDHTFLQKC------HYH 1682 Query: 523 FLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIM 582 H ++ + EF + HYAG+VTY V FLDKN+D + +++ + S+ ++ Sbjct: 1683 ---HGANPLYSKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVV 1739 Query: 583 SQCFD-------------RSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPN 629 + F S ++ + TVA +F+ SLL LVE ++ P ++RC+KPN Sbjct: 1740 AHLFSSHAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPN 1799 Query: 630 DAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGR 689 K+PG F+ ++ Q++Y G+LE +R+R+ GF R ++ F+ RY L Sbjct: 1800 HKKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDL---- 1855 Query: 690 PQDG---VAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLAT-KIQAAW 745 P +G V+VL R P Y++G +K+F++ + L+ +++ +LA +Q Sbjct: 1856 PANGDMCVSVLSRLCKVMPNMYRVGVSKLFLK--EHLYQLLESMREHVLNLAALTLQRCL 1913 Query: 746 RGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLR 797 RGF +++F ++ I +QS RG L R++ + + + R L+ +V R Sbjct: 1914 RGFFIKRRFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSR 1965 >gi|215982794 myosin VA isoform 2 [Homo sapiens] Length = 1828 Score = 453 bits (1166), Expect = e-127 Identities = 284/787 (36%), Positives = 435/787 (55%), Gaps = 59/787 (7%) Query: 46 VGVQDFVLLENFTSEAAFIENLRRRFREN-LIYTYIGPVLVSVNPYRDLQIYSRQHMERY 104 VG D L ++ E A + NLR RF ++ LIYTY G VLV++NPY L IY + Y Sbjct: 69 VGENDLTAL-SYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAY 127 Query: 105 RGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAP 164 G + ++ PH+FAVA+ Y+ + + R+Q++++SGESGAGKT + K ++++A + Sbjct: 128 SGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA 187 Query: 165 ERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEK 224 V +++L SNP++E+ GNAKT RNDNSSRFGKY+++ FD + +G ++ +YLLEK Sbjct: 188 SEAN-VEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEK 246 Query: 225 SRVVHQNHGERNFHIFYQLLEGGE--EETLRRLGLERNPQSYLYLVKGQCAKVSSINDKS 282 SRVV Q ERN+HIFYQL + E + RLG N ++ Y +G + ++D Sbjct: 247 SRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG---NADNFNYTKQGGSPVIEGVDDAK 303 Query: 283 DWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQ-LKYLTRL 341 + R+A T++ +E + I+A +LHLGN+ F + + + + +++ L L Sbjct: 304 EMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCDL 363 Query: 342 LSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL 401 + V+ + L HRK+ E + P++ QA ARDALAK +Y++ F W+V +N++L Sbjct: 364 MGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQAL 423 Query: 402 ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEY 461 S + + + +G+LDIYGFE F+ NSFEQFCINY NEKLQQ F K EQEEY Sbjct: 424 HS------AVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEY 477 Query: 462 EAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHP 521 E I W + +++N+ +L+E K GI+ +LDEEC P + TD T+ +KL +T Sbjct: 478 MKEQIPWTLIDFYDNQPCINLIESKL-GILDLLDEECKMP-KGTDDTWAQKLYNT----- 530 Query: 522 HFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPI 581 H L + + L F + H+A +V Y GFL+KN D +F + + SSK + Sbjct: 531 HLNKCALFE---KPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKM 587 Query: 582 MSQCFDRSELS-----------------------------DKKRPETVATQFKMSLLQLV 612 + + F E + K+ +TV QF+ SL L+ Sbjct: 588 LPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLM 647 Query: 613 EILQSKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFL 672 E L + P YVRCIKPND K P FDE Q++ G+LE +R+ AGF R Y+ F Sbjct: 648 ETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFF 707 Query: 673 QRYKSLCPETWPTWAGRPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEV 732 RY+ L + + R Q VL + L ++Y+ G+TKIF R + + E Sbjct: 708 SRYRVLMKQK-DVLSDRKQTCKNVLEK-LILDKDKYQFGKTKIFFRAGQVAY-LEKLRAD 764 Query: 733 RRQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGR--RKAAKRKWAAQTIRRL 790 + ++ +IQ RG+ R+K+LR++++AI +Q + RG R K +R AA I++ Sbjct: 765 KLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKY 824 Query: 791 IRGFVLR 797 R +V+R Sbjct: 825 WRMYVVR 831 >gi|215982791 myosin VA isoform 1 [Homo sapiens] Length = 1855 Score = 453 bits (1166), Expect = e-127 Identities = 284/787 (36%), Positives = 435/787 (55%), Gaps = 59/787 (7%) Query: 46 VGVQDFVLLENFTSEAAFIENLRRRFREN-LIYTYIGPVLVSVNPYRDLQIYSRQHMERY 104 VG D L ++ E A + NLR RF ++ LIYTY G VLV++NPY L IY + Y Sbjct: 69 VGENDLTAL-SYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAY 127 Query: 105 RGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAP 164 G + ++ PH+FAVA+ Y+ + + R+Q++++SGESGAGKT + K ++++A + Sbjct: 128 SGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA 187 Query: 165 ERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEK 224 V +++L SNP++E+ GNAKT RNDNSSRFGKY+++ FD + +G ++ +YLLEK Sbjct: 188 SEAN-VEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEK 246 Query: 225 SRVVHQNHGERNFHIFYQLLEGGE--EETLRRLGLERNPQSYLYLVKGQCAKVSSINDKS 282 SRVV Q ERN+HIFYQL + E + RLG N ++ Y +G + ++D Sbjct: 247 SRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG---NADNFNYTKQGGSPVIEGVDDAK 303 Query: 283 DWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQ-LKYLTRL 341 + R+A T++ +E + I+A +LHLGN+ F + + + + +++ L L Sbjct: 304 EMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCDL 363 Query: 342 LSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL 401 + V+ + L HRK+ E + P++ QA ARDALAK +Y++ F W+V +N++L Sbjct: 364 MGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQAL 423 Query: 402 ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEY 461 S + + + +G+LDIYGFE F+ NSFEQFCINY NEKLQQ F K EQEEY Sbjct: 424 HS------AVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEY 477 Query: 462 EAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHP 521 E I W + +++N+ +L+E K GI+ +LDEEC P + TD T+ +KL +T Sbjct: 478 MKEQIPWTLIDFYDNQPCINLIESKL-GILDLLDEECKMP-KGTDDTWAQKLYNT----- 530 Query: 522 HFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPI 581 H L + + L F + H+A +V Y GFL+KN D +F + + SSK + Sbjct: 531 HLNKCALFE---KPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKM 587 Query: 582 MSQCFDRSELS-----------------------------DKKRPETVATQFKMSLLQLV 612 + + F E + K+ +TV QF+ SL L+ Sbjct: 588 LPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLM 647 Query: 613 EILQSKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFL 672 E L + P YVRCIKPND K P FDE Q++ G+LE +R+ AGF R Y+ F Sbjct: 648 ETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFF 707 Query: 673 QRYKSLCPETWPTWAGRPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEV 732 RY+ L + + R Q VL + L ++Y+ G+TKIF R + + E Sbjct: 708 SRYRVLMKQK-DVLSDRKQTCKNVLEK-LILDKDKYQFGKTKIFFRAGQVAY-LEKLRAD 764 Query: 733 RRQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGR--RKAAKRKWAAQTIRRL 790 + ++ +IQ RG+ R+K+LR++++AI +Q + RG R K +R AA I++ Sbjct: 765 KLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKY 824 Query: 791 IRGFVLR 797 R +V+R Sbjct: 825 WRMYVVR 831 >gi|122937345 myosin VB [Homo sapiens] Length = 1848 Score = 450 bits (1157), Expect = e-126 Identities = 277/782 (35%), Positives = 430/782 (54%), Gaps = 60/782 (7%) Query: 46 VGVQDFVLLENFTSEAAFIENLRRRFRE-NLIYTYIGPVLVSVNPYRDLQIYSRQHMERY 104 VG D L ++ E A + NL+ RF E N IYTY G VLV++NPY L IY + + Y Sbjct: 69 VGENDLTAL-SYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTY 127 Query: 105 RGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAP 164 G + ++ PH+FAVA+ Y+ + + ++Q++++SGESGAGKT + K ++++A T Sbjct: 128 SGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFA-TVGGS 186 Query: 165 ERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEK 224 + +++L S+P++EA GNAKT RNDNSSRFGKY+ + FD + +G ++ +YLLEK Sbjct: 187 ASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEK 246 Query: 225 SRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDW 284 SRVV Q ERN+HIFYQL + L L + + + Y +G + ++D D+ Sbjct: 247 SRVVFQADDERNYHIFYQLCAAAGLPEFKELAL-TSAEDFFYTSQGGDTSIEGVDDAEDF 305 Query: 285 KVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNA-QVTTEN-QLKYLTRLL 342 + R+A T++ E + I+AS+LHLG++ A + ++ ++ ++ L RLL Sbjct: 306 EKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNFCRLL 365 Query: 343 SVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLA 402 VE S + L HRK++ E + ++L+Q AR+ALAK +Y++ F W+V IN++L Sbjct: 366 GVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALH 425 Query: 403 SKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYE 462 + S + + +G+LDIYGFE F+ NSFEQFCINY NEKLQQ F K EQEEY Sbjct: 426 T------SLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYM 479 Query: 463 AEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPH 522 E I W + +++N+ DL+E K GI+ +LDEEC P + TD + +KL D H Sbjct: 480 KEQIPWTLIDFYDNQPCIDLIEAKL-GILDLLDEECKVP-KGTDQNWAQKLYDRHSSSQH 537 Query: 523 FLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIM 582 F Q+ R S F ++H+A +V Y GFL+KN D ++ + +SK P++ Sbjct: 538 F-------QKPRMS--NTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLV 588 Query: 583 SQCFDRS--------------------------ELSDKKRPETVATQFKMSLLQLVEILQ 616 + F ++S+K+ +TV QF+ SL L+E L Sbjct: 589 ADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLN 648 Query: 617 SKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYK 676 + P YVRCIKPND K P FD Q++ G+LE +R+ AG+ R Y F RY+ Sbjct: 649 ATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYR 708 Query: 677 SLCPETWPTWAGRPQDGVA-VLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQ 735 L + A + + ++ +L P++++ GRTKIF R + + E + + Sbjct: 709 VLVKKR--ELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAY-LEKLRADKFR 765 Query: 736 SLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFV 795 + IQ RG+ + K+ R+K + + +Q + RG L RR A+ +RR+ V Sbjct: 766 TATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARR-------LAEHLRRIRAAVV 818 Query: 796 LR 797 L+ Sbjct: 819 LQ 820 Score = 33.5 bits (75), Expect = 1.1 Identities = 49/209 (23%), Positives = 81/209 (38%), Gaps = 24/209 (11%) Query: 608 LLQLVEILQSKEPAYVRCIKPNDAKQPGRFD----EVLIRH-QVKYLGLLENLRVRRAGF 662 L++ E+ + + A R + N K P +F ++ R QV YL L + R A Sbjct: 710 LVKKRELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATI 769 Query: 663 AYRRKYEAFLQR--YKSLCPETWPTWAGRPQDGVAVLVRHLG------YKPEEYKMGRTK 714 ++ +LQ+ Y L T L HL + Y+M R + Sbjct: 770 MIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRAR 829 Query: 715 -----------IFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRVKRSAIC 763 + F + +F +V + AT IQ RG+ R+ F R++ +AI Sbjct: 830 QAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIV 889 Query: 764 IQSWWRGTLGRRKAAKRKWAAQTIRRLIR 792 IQ +R RR+ + A++ L R Sbjct: 890 IQCAFRMLKARRELKALRIEARSAEHLKR 918 >gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo sapiens] Length = 1935 Score = 444 bits (1142), Expect = e-124 Identities = 271/746 (36%), Positives = 408/746 (54%), Gaps = 42/746 (5%) Query: 48 VQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGV 107 ++D +L F E A + NL+ R+ +IYTY G V+VNPY+ L +Y+ + + YRG Sbjct: 87 IEDMAML-TFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGK 145 Query: 108 SFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERG 167 E PPH+F+++D Y+ + T+R +Q+++I+GESGAGKT TKR++Q++A +R Sbjct: 146 KRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRS 205 Query: 168 --------GAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILS 219 G + D+++Q+NP LEAFGNAKT+RNDNSSRFGK++ + F G I + Sbjct: 206 KKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIET 265 Query: 220 YLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSIN 279 YLLEKSRV+ Q ER++HIFYQ+L + E L L + NP Y ++ +G+ V+SI+ Sbjct: 266 YLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGE-TTVASID 324 Query: 280 DKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANE-ESNAQVTTENQLKYL 338 D + A V+ FT +E + + +++H GN+ F + E A+ + Sbjct: 325 DAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKS 384 Query: 339 TRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKIN 398 L+ + + L + L H ++ E + N++Q YA ALAKAVY R F W+V +IN Sbjct: 385 AYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRIN 444 Query: 399 RSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQ 458 +L +K +G+LDI GFE+F NSFEQ CIN+ NEKLQQ F EQ Sbjct: 445 ATLETKQPRQ------YFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQ 498 Query: 459 EEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVK 518 EEY+ EGI W + + + C + EK GI+SIL+EEC+ P +ATD+TF KL D Sbjct: 499 EEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFP-KATDMTFKAKLFD--- 554 Query: 519 HHPHFLTHKLADQRTRKSLGRGE--FRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCS 576 + L Q+ R G+ E F L+HYAG V Y++ G+L KN D L + Sbjct: 555 ---NHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQK 611 Query: 577 SKNPIMSQCF----------DRSELSDKKRP--ETVATQFKMSLLQLVEILQSKEPAYVR 624 S ++S F ++ + KK +TV+ + +L +L+ L+S P +VR Sbjct: 612 SSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVR 671 Query: 625 CIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWP 684 CI PN+ K PG D L+ HQ++ G+LE +R+ R GF R Y F QRY+ L P P Sbjct: 672 CIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIP 731 Query: 685 TWAG-RPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQA 743 + G L+ L +YK G TK+F + L E+ + R + T+IQA Sbjct: 732 EGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFK-AGLLGLLEEMRDERLSRIITRIQA 790 Query: 744 AWRGFHWRQKFLRV--KRSAICIQSW 767 RG R ++ ++ +R ++ + W Sbjct: 791 QSRGVLARMEYKKLLERRDSLLVIQW 816 >gi|156104908 myosin heavy chain 6 [Homo sapiens] Length = 1939 Score = 444 bits (1141), Expect = e-124 Identities = 271/748 (36%), Positives = 409/748 (54%), Gaps = 44/748 (5%) Query: 48 VQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGV 107 ++D +L F E A + NL+ R+ +IYTY G V+VNPY+ L +Y+ + + YRG Sbjct: 87 IEDMAML-TFLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGK 145 Query: 108 SFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERG 167 E PPH+F+++D Y+ + T+R +Q+++I+GESGAGKT TKR++Q++A +RG Sbjct: 146 KRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRG 205 Query: 168 ---------GAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHIL 218 G + D+++Q+NP LEAFGNAKT+RNDNSSRFGK++ + F G I Sbjct: 206 KKDNANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIE 265 Query: 219 SYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSI 278 +YLLEKSRV+ Q ERN+HIFYQ+L + E L L + NP Y ++ +G+ V+SI Sbjct: 266 TYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGE-VSVASI 324 Query: 279 NDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANE-ESNAQVTTENQLKY 337 +D + A V+ FT +E + + +++H GN+ F + E A+ Sbjct: 325 DDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADK 384 Query: 338 LTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKI 397 L+ + + L + L H ++ E + +++Q Y+ ALAKAVY + F W+V +I Sbjct: 385 SAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRI 444 Query: 398 NRSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSE 457 N +L +K +G+LDI GFE+F NSFEQ CIN+ NEKLQQ F E Sbjct: 445 NATLETKQPRQ------YFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLE 498 Query: 458 QEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTV 517 QEEY+ EGI W + + + C + EK GI+SIL+EEC+ P +ATD+TF KL D Sbjct: 499 QEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFP-KATDMTFKAKLYD-- 555 Query: 518 KHHPHFLTHKLADQRTRKSLGRGE--FRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMC 575 + L Q+ R G+ E F L+HYAG V Y++ G+L+KN D L + Sbjct: 556 ----NHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQ 611 Query: 576 SSKNPIMSQCFDRSELSD----------KKRP---ETVATQFKMSLLQLVEILQSKEPAY 622 S +M+ F +D KK+ +TV+ + +L +L+ L++ P + Sbjct: 612 KSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHF 671 Query: 623 VRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPET 682 VRCI PN+ K PG D L+ HQ++ G+LE +R+ R GF R Y F QRY+ L P Sbjct: 672 VRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVA 731 Query: 683 WPTWAG-RPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKI 741 P + G L+ L +YK G TK+F + L E+ + R + T++ Sbjct: 732 IPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFK-AGLLGLLEEMRDERLSRIITRM 790 Query: 742 QAAWRGFHWRQKFLRV--KRSAICIQSW 767 QA RG R +F ++ +R A+ + W Sbjct: 791 QAQARGQLMRIEFKKIVERRDALLVIQW 818 >gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] Length = 1976 Score = 435 bits (1119), Expect = e-121 Identities = 268/754 (35%), Positives = 410/754 (54%), Gaps = 46/754 (6%) Query: 59 SEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFA 118 +EA+ + NL+ R+ LIYTY G V +NPY++L IYS +E YRG +E+PPH++A Sbjct: 97 NEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYA 156 Query: 119 VADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER------GGAVRD 172 ++++ YR + +R DQ+++ +GESGAGKTE TK+++Q+ A + + G + Sbjct: 157 ISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIPGELER 216 Query: 173 RLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNH 232 +LLQ+NP+LE+FGNAKT++NDNSSRFGK++ + FD G VG +I +YLLEKSR V Q Sbjct: 217 QLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAK 276 Query: 233 GERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALT 292 ER FHIFYQLL G E L LE +Y +L G + DK +++ +A+ Sbjct: 277 DERTFHIFYQLLSGAGEHLKSDLLLE-GFNNYRFLSNGY-IPIPGQQDKDNFQETMEAMH 334 Query: 293 VIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQL-KYLTRLLSVEGSTLRE 351 ++ F+ +E+ +L +V+SVL GNI F ++ EN + + L LL + Sbjct: 335 IMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTR 394 Query: 352 ALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLASKDVESPSW 411 A+ +I + + EQA +A +ALAKA Y R F WLV +IN++L + Sbjct: 395 AILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKAL-----DRTKR 449 Query: 412 RSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPV 471 + + +G+LDI GFE+F+ NSFEQ CINY NEKLQQLF EQEEY+ EGI W + Sbjct: 450 QGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFI 509 Query: 472 QYFNNKIIC-DLVEEKFK--GIISILDEECLRPGEATDLTFLEKLEDTVKHHPHFLTHKL 528 + + C DL+E G++++LDEEC P +ATD TF+EKL H F Sbjct: 510 DFGLDLQPCIDLIERPANPPGVLALLDEECWFP-KATDKTFVEKLVQEQGSHSKF----- 563 Query: 529 ADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMSQ---- 584 Q+ R+ + +F ++HYAG+V Y +L KN D L N+ + S + +++ Sbjct: 564 --QKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKD 621 Query: 585 ----------------CFDRSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKP 628 F + + K TV +K SL +L+ L++ P +VRCI P Sbjct: 622 VDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIP 681 Query: 629 NDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAG 688 N K+ G+ D L+ Q++ G+LE +R+ R GF R ++ F QRY+ L P P Sbjct: 682 NHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFM 741 Query: 689 RPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGF 748 + ++R L P Y++G++KIF R L E+ +++ + QA RG+ Sbjct: 742 DGKQACERMIRALELDPNLYRIGQSKIFFR-AGVLAHLEEERDLKITDIIIFFQAVCRGY 800 Query: 749 HWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKW 782 R+ F + ++ ++ R K +W Sbjct: 801 LARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQW 834 >gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] Length = 1995 Score = 434 bits (1115), Expect = e-121 Identities = 279/753 (37%), Positives = 415/753 (55%), Gaps = 47/753 (6%) Query: 59 SEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFA 118 +EA+ + NLR R+ LIYTY G V +NPY+ L IY+ +E YRG +EVPPH++A Sbjct: 117 NEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYA 176 Query: 119 VADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAP----ERG--GAVRD 172 V + YR++ +R DQ+++ +GESGAGKTE TK+++Q+ A +P E G G + Sbjct: 177 VTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPGELER 236 Query: 173 RLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNH 232 +LLQ+NP+LEAFGNAKT++NDNSSRFGK++ + FD G VG +I +YLLEKSR + Q Sbjct: 237 QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAK 296 Query: 233 GERNFHIFYQLLEGGEEETLRRLGLERNPQS-YLYLVKGQCAKVSSINDKSDWKVVRKAL 291 E +FHIFYQLL G E+ L LE P S Y +L G + S ++ ++ ++L Sbjct: 297 DECSFHIFYQLLGGAGEQLKADLLLE--PCSHYRFLTNGPSS--SPGQERELFQETLESL 352 Query: 292 TVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTEN-QLKYLTRLLSVEGSTLR 350 V+ F+ +E+ +L +V++VL GNI ++ +N + L RLL + + Sbjct: 353 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 412 Query: 351 EALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLASKDVESPS 410 AL +I + + EQA +A +ALAKA Y R F WLV ++NR+L + S Sbjct: 413 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 472 Query: 411 WRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEP 470 + LG+LDI GFE+FQ NSFEQ CINY NEKLQQLF EQEEY+ EGI W Sbjct: 473 F-----LGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTF 527 Query: 471 VQYFNNKIIC-DLVEEKFK--GIISILDEECLRPGEATDLTFLEKLEDTVKHHPHFLTHK 527 + + + C DL+E G++++LDEEC P +ATD +F+EK+ HP F Sbjct: 528 LDFGLDLQPCIDLIERPANPPGLLALLDEECWFP-KATDKSFVEKVAQEQGGHPKF---- 582 Query: 528 LADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMSQCF- 586 QR R + +F +LHYAG+V Y +L KN D L N+ + S + + ++ + Sbjct: 583 ---QRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 639 Query: 587 ---------DRSELSDKK---RP-----ETVATQFKMSLLQLVEILQSKEPAYVRCIKPN 629 S L D RP TV +K SL +L+ L + P++VRCI PN Sbjct: 640 DVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPN 699 Query: 630 DAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGR 689 K+ G+ + L+ Q++ G+LE +R+ R GF R ++ F QRY+ L P P Sbjct: 700 HEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMD 759 Query: 690 PQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFH 749 + +++ L P Y++G++KIF R L E+ +++ + QAA RG+ Sbjct: 760 GKQACEKMIQALELDPNLYRVGQSKIFFR-AGVLAQLEEERDLKVTDIIVSFQAAARGYL 818 Query: 750 WRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKW 782 R+ F + ++ ++ R K +W Sbjct: 819 ARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQW 851 >gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo sapiens] Length = 1940 Score = 431 bits (1109), Expect = e-120 Identities = 269/747 (36%), Positives = 410/747 (54%), Gaps = 47/747 (6%) Query: 48 VQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGV 107 ++D +L + +E A + NL+ R+ +IYTY G V+VNPY+ L +Y+ + +E YRG Sbjct: 88 IEDMAMLTHL-NEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGK 146 Query: 108 SFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERG 167 E PPH+F+++D Y+ + T+R +Q+++I+GESGAGKT TKR++Q++A + Sbjct: 147 KRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLA 206 Query: 168 --------GAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILS 219 G + D+++ +NP+LEAFGNAKT+RNDNSSRFGK++ + F G I + Sbjct: 207 KKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 266 Query: 220 YLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSIN 279 YLLEKSRV Q ER++HIFYQ+L + E + L + NP Y ++ +G+ V+SI+ Sbjct: 267 YLLEKSRVTFQLKAERSYHIFYQILSNKKPELIELLLITTNPYDYPFISQGEIL-VASID 325 Query: 280 DKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANE-ESNAQVTTENQLKYL 338 D + A+ ++ FT +E L + +V+H GN+ F + E A+ Sbjct: 326 DAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKT 385 Query: 339 TRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKIN 398 L+ + S L +AL ++ E + ++Q +A +AL+K+VY + F W+V +IN Sbjct: 386 AYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRIN 445 Query: 399 RSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQ 458 + L D + P +G+LDI GFE+F++NS EQ CIN+ NEKLQQ F EQ Sbjct: 446 QQL---DTKLPRQH---FIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQ 499 Query: 459 EEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVK 518 EEY+ EGI W + + + C + EK GI SIL+EEC+ P +ATD +F KL D Sbjct: 500 EEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFP-KATDTSFKNKLYD--- 555 Query: 519 HHPHFLTHKLADQRTRKSLGRGE--FRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCS 576 L Q+ + GR E F L+HYAG V YSV+G+L+KN D L + Sbjct: 556 ---QHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQK 612 Query: 577 SKNPIMSQCFDRSELSD----KKRP--------ETVATQFKMSLLQLVEILQSKEPAYVR 624 S N +++ + +D KK+ +TV+ F+ +L +L+ L++ P +VR Sbjct: 613 SSNRLLAHLYATFATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVR 672 Query: 625 CIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWP 684 CI PN+ K PG + L+ HQ++ G+LE +R+ R GF R Y F QRY+ L P Sbjct: 673 CIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIP 732 Query: 685 TWAGRPQDGVAV---LVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKI 741 G+ D L+ + +YK G TK+F + L E+ + R L T+ Sbjct: 733 --EGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFK-AGLLGTLEEMRDDRLAKLITRT 789 Query: 742 QAAWRGFHWR---QKFLRVKRSAICIQ 765 QA RGF R QK ++ + S CIQ Sbjct: 790 QAVCRGFLMRVEFQKMVQRRESIFCIQ 816 >gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] Length = 2003 Score = 431 bits (1107), Expect = e-120 Identities = 279/761 (36%), Positives = 415/761 (54%), Gaps = 55/761 (7%) Query: 59 SEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFA 118 +EA+ + NLR R+ LIYTY G V +NPY+ L IY+ +E YRG +EVPPH++A Sbjct: 117 NEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYA 176 Query: 119 VADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAP----ERG------- 167 V + YR++ +R DQ+++ +GESGAGKTE TK+++Q+ A +P E G Sbjct: 177 VTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVST 236 Query: 168 ---GAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEK 224 G + +LLQ+NP+LEAFGNAKT++NDNSSRFGK++ + FD G VG +I +YLLEK Sbjct: 237 VSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEK 296 Query: 225 SRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQS-YLYLVKGQCAKVSSINDKSD 283 SR + Q E +FHIFYQLL G E+ L LE P S Y +L G + S ++ Sbjct: 297 SRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLE--PCSHYRFLTNGPSS--SPGQEREL 352 Query: 284 WKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTEN-QLKYLTRLL 342 ++ ++L V+ F+ +E+ +L +V++VL GNI ++ +N + L RLL Sbjct: 353 FQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLL 412 Query: 343 SVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLA 402 + + AL +I + + EQA +A +ALAKA Y R F WLV ++NR+L Sbjct: 413 GLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD 472 Query: 403 SKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYE 462 + S+ LG+LDI GFE+FQ NSFEQ CINY NEKLQQLF EQEEY+ Sbjct: 473 RSPRQGASF-----LGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQ 527 Query: 463 AEGIAWEPVQYFNNKIIC-DLVEEKFK--GIISILDEECLRPGEATDLTFLEKLEDTVKH 519 EGI W + + + C DL+E G++++LDEEC P +ATD +F+EK+ Sbjct: 528 REGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFP-KATDKSFVEKVAQEQGG 586 Query: 520 HPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKN 579 HP F QR R + +F +LHYAG+V Y +L KN D L N+ + S + Sbjct: 587 HPKF-------QRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTD 639 Query: 580 PIMSQCF----------DRSELSDKK---RP-----ETVATQFKMSLLQLVEILQSKEPA 621 + ++ + S L D RP TV +K SL +L+ L + P+ Sbjct: 640 RLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPS 699 Query: 622 YVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPE 681 +VRCI PN K+ G+ + L+ Q++ G+LE +R+ R GF R ++ F QRY+ L P Sbjct: 700 FVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPN 759 Query: 682 TWPTWAGRPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKI 741 P + +++ L P Y++G++KIF R L E+ +++ + Sbjct: 760 AIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFR-AGVLAQLEEERDLKVTDIIVSF 818 Query: 742 QAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKW 782 QAA RG+ R+ F + ++ ++ R K +W Sbjct: 819 QAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQW 859 >gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo sapiens] Length = 1972 Score = 429 bits (1103), Expect = e-120 Identities = 261/754 (34%), Positives = 419/754 (55%), Gaps = 46/754 (6%) Query: 59 SEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFA 118 +EA+ + NLR R+ LIYTY G V VNPY+ L IYS + ++ Y+G +E+PPH++A Sbjct: 97 NEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYA 156 Query: 119 VADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER------GGAVRD 172 +ADT YR++ +R DQ+++ +GESGAGKTE TK+++Q+ A + + G + Sbjct: 157 IADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEK 216 Query: 173 RLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNH 232 +LLQ+NP+LEAFGNAKT++NDNSSRFGK++ + FD G VG +I +YLLEKSR + Q Sbjct: 217 QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAR 276 Query: 233 GERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALT 292 ER FHIFY ++ G +E+ L LE +Y +L G + + D ++ +A+ Sbjct: 277 DERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNG-FVPIPAAQDDEMFQETVEAMA 334 Query: 293 VIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN-AQVTTENQLKYLTRLLSVEGSTLRE 351 ++ F+E+E +L +V+SVL LGNI F ++ A + + + L+ + + Sbjct: 335 IMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTR 394 Query: 352 ALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLASKDVESPSW 411 ++ +I + + EQA +A +ALAKA Y R F W++ ++N++L + S+ Sbjct: 395 SILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASF 454 Query: 412 RSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPV 471 LG+LDI GFE+F+ NSFEQ CINY NEKLQQLF EQEEY+ EGI W + Sbjct: 455 -----LGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFI 509 Query: 472 QYFNNKIIC-DLVEEKFK--GIISILDEECLRPGEATDLTFLEKLEDTVKHHPHFLTHKL 528 + + C +L+E G++++LDEEC P +ATD +F+EKL HP F Sbjct: 510 DFGLDLQPCIELIERPNNPPGVLALLDEECWFP-KATDKSFVEKLCTEQGSHPKF----- 563 Query: 529 ADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMSQCF-- 586 Q+ ++ + EF ++HYAG+V Y+ + +L KN D L N+ + +S + ++ + Sbjct: 564 --QKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKD 621 Query: 587 -DR-------SELSDKKRP----------ETVATQFKMSLLQLVEILQSKEPAYVRCIKP 628 DR +++++ P TV +K L +L+ L++ P +VRCI P Sbjct: 622 VDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIP 681 Query: 629 NDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAG 688 N K+ G+ D L+ Q++ G+LE +R+ R GF R ++ F QRY+ L P Sbjct: 682 NHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFM 741 Query: 689 RPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGF 748 + ++++ L P Y++G++KIF R L E+ +++ + QA RG+ Sbjct: 742 DGKQACILMIKALELDPNLYRIGQSKIFFR-TGVLAHLEEERDLKITDVIMAFQAMCRGY 800 Query: 749 HWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKW 782 R+ F + ++ ++ R K +W Sbjct: 801 LARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQW 834 >gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo sapiens] Length = 1938 Score = 429 bits (1103), Expect = e-120 Identities = 261/754 (34%), Positives = 419/754 (55%), Gaps = 46/754 (6%) Query: 59 SEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFA 118 +EA+ + NLR R+ LIYTY G V VNPY+ L IYS + ++ Y+G +E+PPH++A Sbjct: 97 NEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYA 156 Query: 119 VADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER------GGAVRD 172 +ADT YR++ +R DQ+++ +GESGAGKTE TK+++Q+ A + + G + Sbjct: 157 IADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEK 216 Query: 173 RLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNH 232 +LLQ+NP+LEAFGNAKT++NDNSSRFGK++ + FD G VG +I +YLLEKSR + Q Sbjct: 217 QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAR 276 Query: 233 GERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALT 292 ER FHIFY ++ G +E+ L LE +Y +L G + + D ++ +A+ Sbjct: 277 DERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNG-FVPIPAAQDDEMFQETVEAMA 334 Query: 293 VIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN-AQVTTENQLKYLTRLLSVEGSTLRE 351 ++ F+E+E +L +V+SVL LGNI F ++ A + + + L+ + + Sbjct: 335 IMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTR 394 Query: 352 ALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLASKDVESPSW 411 ++ +I + + EQA +A +ALAKA Y R F W++ ++N++L + S+ Sbjct: 395 SILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASF 454 Query: 412 RSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPV 471 LG+LDI GFE+F+ NSFEQ CINY NEKLQQLF EQEEY+ EGI W + Sbjct: 455 -----LGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFI 509 Query: 472 QYFNNKIIC-DLVEEKFK--GIISILDEECLRPGEATDLTFLEKLEDTVKHHPHFLTHKL 528 + + C +L+E G++++LDEEC P +ATD +F+EKL HP F Sbjct: 510 DFGLDLQPCIELIERPNNPPGVLALLDEECWFP-KATDKSFVEKLCTEQGSHPKF----- 563 Query: 529 ADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMSQCF-- 586 Q+ ++ + EF ++HYAG+V Y+ + +L KN D L N+ + +S + ++ + Sbjct: 564 --QKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKD 621 Query: 587 -DR-------SELSDKKRP----------ETVATQFKMSLLQLVEILQSKEPAYVRCIKP 628 DR +++++ P TV +K L +L+ L++ P +VRCI P Sbjct: 622 VDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIP 681 Query: 629 NDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAG 688 N K+ G+ D L+ Q++ G+LE +R+ R GF R ++ F QRY+ L P Sbjct: 682 NHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFM 741 Query: 689 RPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGF 748 + ++++ L P Y++G++KIF R L E+ +++ + QA RG+ Sbjct: 742 DGKQACILMIKALELDPNLYRIGQSKIFFR-TGVLAHLEEERDLKITDVIMAFQAMCRGY 800 Query: 749 HWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKW 782 R+ F + ++ ++ R K +W Sbjct: 801 LARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQW 834 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.136 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 38,734,702 Number of Sequences: 37866 Number of extensions: 1686799 Number of successful extensions: 4522 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 66 Number of HSP's successfully gapped in prelim test: 14 Number of HSP's that attempted gapping in prelim test: 3923 Number of HSP's gapped (non-prelim): 213 length of query: 1063 length of database: 18,247,518 effective HSP length: 113 effective length of query: 950 effective length of database: 13,968,660 effective search space: 13270227000 effective search space used: 13270227000 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.