Guide to the Human Genome
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Search of human proteins with 38348215

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38348215 embigin [Homo sapiens]
         (327 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38348215 embigin [Homo sapiens]                                    662   0.0  
gi|9257240 neuroplastin isoform a precursor [Homo sapiens]             69   6e-12
gi|6912646 neuroplastin isoform b precursor [Homo sapiens]             69   6e-12
gi|38372919 basigin isoform 1 precursor [Homo sapiens]                 67   2e-11
gi|38372925 basigin isoform 2 precursor [Homo sapiens]                 67   2e-11
gi|238624149 neuroplastin isoform d precursor [Homo sapiens]           67   2e-11
gi|238624147 neuroplastin isoform c precursor [Homo sapiens]           67   2e-11
gi|38372923 basigin isoform 4 [Homo sapiens]                           62   9e-10
gi|110349719 titin isoform N2-A [Homo sapiens]                         51   1e-06
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]         47   3e-05
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    47   3e-05
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ...    47   3e-05
gi|157168355 CD22 molecule [Homo sapiens]                              42   7e-04
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42...    42   7e-04
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                    41   0.001
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]                    41   0.001
gi|118572606 hemicentin 1 [Homo sapiens]                               41   0.001
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi...    39   0.006
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap...    39   0.006
gi|54607118 leucine-rich repeats and immunoglobulin-like domains...    39   0.008
gi|33519481 neural cell adhesion molecule 2 precursor [Homo sapi...    38   0.014
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact...    37   0.018
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac...    37   0.018
gi|4507875 vascular cell adhesion molecule 1 isoform a precursor...    36   0.041
gi|166295173 kin of IRRE like [Homo sapiens]                           36   0.041
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]             36   0.053
gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo sap...    36   0.053
gi|7657361 contactin 6 [Homo sapiens]                                  36   0.053
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa...    35   0.091
gi|9624969 butyrophilin-like 2 [Homo sapiens]                          35   0.12 

>gi|38348215 embigin [Homo sapiens]
          Length = 327

 Score =  662 bits (1707), Expect = 0.0
 Identities = 327/327 (100%), Positives = 327/327 (100%)

Query: 1   MRALPGLLEARARTPRLLLLQCLLAAARPSSADGSAPDSPFTSPPLREEIMANNFSLESH 60
           MRALPGLLEARARTPRLLLLQCLLAAARPSSADGSAPDSPFTSPPLREEIMANNFSLESH
Sbjct: 1   MRALPGLLEARARTPRLLLLQCLLAAARPSSADGSAPDSPFTSPPLREEIMANNFSLESH 60

Query: 61  NISLTEHSSMPVEKNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATG 120
           NISLTEHSSMPVEKNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATG
Sbjct: 61  NISLTEHSSMPVEKNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATG 120

Query: 121 STLYTQYRFTIINSKQMGSYSCFFREEKEQRGTFNFKVPELHGKNKPLISYVGDSTVLTC 180
           STLYTQYRFTIINSKQMGSYSCFFREEKEQRGTFNFKVPELHGKNKPLISYVGDSTVLTC
Sbjct: 121 STLYTQYRFTIINSKQMGSYSCFFREEKEQRGTFNFKVPELHGKNKPLISYVGDSTVLTC 180

Query: 181 KCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRAL 240
           KCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRAL
Sbjct: 181 KCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRAL 240

Query: 241 FQLGESEEHIELVVLSYLVPLKPFLVIVAEVILLVATILLCEKYTQKKKKHSDEGKEFEQ 300
           FQLGESEEHIELVVLSYLVPLKPFLVIVAEVILLVATILLCEKYTQKKKKHSDEGKEFEQ
Sbjct: 241 FQLGESEEHIELVVLSYLVPLKPFLVIVAEVILLVATILLCEKYTQKKKKHSDEGKEFEQ 300

Query: 301 IEQLKSDDSNGIENNVPRHRKNESLGQ 327
           IEQLKSDDSNGIENNVPRHRKNESLGQ
Sbjct: 301 IEQLKSDDSNGIENNVPRHRKNESLGQ 327


>gi|9257240 neuroplastin isoform a precursor [Homo sapiens]
          Length = 282

 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 63/242 (26%), Positives = 101/242 (41%), Gaps = 17/242 (7%)

Query: 84  VNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYT-QYRFTIINSKQMGSYSC 142
           V L C  T+S      +  W K+G +L      SAT       +YR     ++  G Y C
Sbjct: 50  VTLQCNLTSSSHTLTYSY-WTKNGVEL------SATRKNASNMEYRINKPRAEDSGEYHC 102

Query: 143 FFREEKEQRGTFNFKV---PELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSS-NGS 198
            +      +     +V   P++ G  +      G    + CK       +W W    NG 
Sbjct: 103 VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGM 162

Query: 199 VKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVLSYL 258
               V      ++IN     E  +   Q+ E+ GE Y C A   +G +     L V S+L
Sbjct: 163 PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGE-YECNATNAIGSASVVTVLRVRSHL 221

Query: 259 VPLKPFLVIVAEVILLVATILLCEKYTQKKKKHSDEGKEFEQIEQLKSDDSNGIENNVPR 318
            PL PFL I+AE+I+LV  I++ E    K+K+  +   + E    +K++ +N  ++   R
Sbjct: 222 APLWPFLGILAEIIILVVIIVVYE----KRKRPDEVPDDDEPAGPMKTNSTNNHKDKNLR 277

Query: 319 HR 320
            R
Sbjct: 278 QR 279


>gi|6912646 neuroplastin isoform b precursor [Homo sapiens]
          Length = 398

 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 63/242 (26%), Positives = 101/242 (41%), Gaps = 17/242 (7%)

Query: 84  VNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYT-QYRFTIINSKQMGSYSC 142
           V L C  T+S      +  W K+G +L      SAT       +YR     ++  G Y C
Sbjct: 166 VTLQCNLTSSSHTLTYSY-WTKNGVEL------SATRKNASNMEYRINKPRAEDSGEYHC 218

Query: 143 FFREEKEQRGTFNFKV---PELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSS-NGS 198
            +      +     +V   P++ G  +      G    + CK       +W W    NG 
Sbjct: 219 VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGM 278

Query: 199 VKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVLSYL 258
               V      ++IN     E  +   Q+ E+ GE Y C A   +G +     L V S+L
Sbjct: 279 PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGE-YECNATNAIGSASVVTVLRVRSHL 337

Query: 259 VPLKPFLVIVAEVILLVATILLCEKYTQKKKKHSDEGKEFEQIEQLKSDDSNGIENNVPR 318
            PL PFL I+AE+I+LV  I++ E    K+K+  +   + E    +K++ +N  ++   R
Sbjct: 338 APLWPFLGILAEIIILVVIIVVYE----KRKRPDEVPDDDEPAGPMKTNSTNNHKDKNLR 393

Query: 319 HR 320
            R
Sbjct: 394 QR 395


>gi|38372919 basigin isoform 1 precursor [Homo sapiens]
          Length = 385

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 66/216 (30%), Positives = 96/216 (44%), Gaps = 33/216 (15%)

Query: 82  SNVNLTCQFTTSGDLNAVNVT---WKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMG 138
           S + LTC    S    A  VT   W K G  L+ + L          +  F + +  Q G
Sbjct: 151 SKILLTCSLNDS----ATEVTGHRWLKGGVVLKEDALPGQ-------KTEFKVDSDDQWG 199

Query: 139 SYSCFFREEKEQRGTFNFKVPELHGKNKPLISYV--------GDSTVLTCKCQNCFPL-N 189
            YSC F  E    GT N    +LHG   P +  V        G++ +L CK ++  P+ +
Sbjct: 200 EYSCVFLPEP--MGTANI---QLHGP--PRVKAVKSSEHINEGETAMLVCKSESVPPVTD 252

Query: 190 WTWYSSNGSV-KVPVGVQMNKYVINGTYANETKLKITQL-LEEDGESYWCRALFQLGESE 247
           W WY    S  K  +    +++ ++ +    ++L I  L +E D   Y C      G  +
Sbjct: 253 WAWYKITDSEDKALMNGSESRFFVSSSQGR-SELHIENLNMEADPGQYRCNGTSSKGSDQ 311

Query: 248 EHIELVVLSYLVPLKPFLVIVAEVILLVATILLCEK 283
             I L V S+L  L PFL IVAEV++LV  I + EK
Sbjct: 312 AIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEK 347


>gi|38372925 basigin isoform 2 precursor [Homo sapiens]
          Length = 269

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 66/216 (30%), Positives = 96/216 (44%), Gaps = 33/216 (15%)

Query: 82  SNVNLTCQFTTSGDLNAVNVT---WKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMG 138
           S + LTC    S    A  VT   W K G  L+ + L          +  F + +  Q G
Sbjct: 35  SKILLTCSLNDS----ATEVTGHRWLKGGVVLKEDALPGQ-------KTEFKVDSDDQWG 83

Query: 139 SYSCFFREEKEQRGTFNFKVPELHGKNKPLISYV--------GDSTVLTCKCQNCFPL-N 189
            YSC F  E    GT N    +LHG   P +  V        G++ +L CK ++  P+ +
Sbjct: 84  EYSCVFLPEP--MGTANI---QLHGP--PRVKAVKSSEHINEGETAMLVCKSESVPPVTD 136

Query: 190 WTWYSSNGSV-KVPVGVQMNKYVINGTYANETKLKITQL-LEEDGESYWCRALFQLGESE 247
           W WY    S  K  +    +++ ++ +    ++L I  L +E D   Y C      G  +
Sbjct: 137 WAWYKITDSEDKALMNGSESRFFVSSSQGR-SELHIENLNMEADPGQYRCNGTSSKGSDQ 195

Query: 248 EHIELVVLSYLVPLKPFLVIVAEVILLVATILLCEK 283
             I L V S+L  L PFL IVAEV++LV  I + EK
Sbjct: 196 AIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEK 231


>gi|238624149 neuroplastin isoform d precursor [Homo sapiens]
          Length = 278

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 65/249 (26%), Positives = 101/249 (40%), Gaps = 29/249 (11%)

Query: 84  VNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYT-QYRFTIINSKQMGSYSC 142
           V L C  T+S      +  W K+G +L      SAT       +YR     ++  G Y C
Sbjct: 50  VTLQCNLTSSSHTLTYSY-WTKNGVEL------SATRKNASNMEYRINKPRAEDSGEYHC 102

Query: 143 FFREEKEQRGTFNFKV---PELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSS-NGS 198
            +      +     +V   P++ G  +      G    + CK       +W W    NG 
Sbjct: 103 VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGM 162

Query: 199 VKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVLSYL 258
               V      ++IN     E  +   Q+ E+ GE Y C A   +G +     L V S+L
Sbjct: 163 PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGE-YECNATNAIGSASVVTVLRVRSHL 221

Query: 259 VPLKPFLVIVAEVILLVATILLCEKYTQKKKKHSDEGKEFEQIEQLKSDDSNGIENNVPR 318
            PL PFL I+AE+I+LV  I++ E     K+K  DE             D+  ++ N   
Sbjct: 222 APLWPFLGILAEIIILVVIIVVYE-----KRKRPDE-----------VPDAGPMKTNSTN 265

Query: 319 HRKNESLGQ 327
           + K+++L Q
Sbjct: 266 NHKDKNLRQ 274


>gi|238624147 neuroplastin isoform c precursor [Homo sapiens]
          Length = 394

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 65/249 (26%), Positives = 101/249 (40%), Gaps = 29/249 (11%)

Query: 84  VNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYT-QYRFTIINSKQMGSYSC 142
           V L C  T+S      +  W K+G +L      SAT       +YR     ++  G Y C
Sbjct: 166 VTLQCNLTSSSHTLTYSY-WTKNGVEL------SATRKNASNMEYRINKPRAEDSGEYHC 218

Query: 143 FFREEKEQRGTFNFKV---PELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSS-NGS 198
            +      +     +V   P++ G  +      G    + CK       +W W    NG 
Sbjct: 219 VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGM 278

Query: 199 VKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVLSYL 258
               V      ++IN     E  +   Q+ E+ GE Y C A   +G +     L V S+L
Sbjct: 279 PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGE-YECNATNAIGSASVVTVLRVRSHL 337

Query: 259 VPLKPFLVIVAEVILLVATILLCEKYTQKKKKHSDEGKEFEQIEQLKSDDSNGIENNVPR 318
            PL PFL I+AE+I+LV  I++ E     K+K  DE             D+  ++ N   
Sbjct: 338 APLWPFLGILAEIIILVVIIVVYE-----KRKRPDE-----------VPDAGPMKTNSTN 381

Query: 319 HRKNESLGQ 327
           + K+++L Q
Sbjct: 382 NHKDKNLRQ 390


>gi|38372923 basigin isoform 4 [Homo sapiens]
          Length = 205

 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 52/159 (32%), Positives = 76/159 (47%), Gaps = 19/159 (11%)

Query: 136 QMGSYSCFFREEKEQRGTFNFKVPELHGKNKPLISYV--------GDSTVLTCKCQNCFP 187
           Q G YSC F  E    GT N    +LHG   P +  V        G++ +L CK ++  P
Sbjct: 17  QWGEYSCVFLPEP--MGTANI---QLHGP--PRVKAVKSSEHINEGETAMLVCKSESVPP 69

Query: 188 L-NWTWYSSNGSV-KVPVGVQMNKYVINGTYANETKLKITQL-LEEDGESYWCRALFQLG 244
           + +W WY    S  K  +    +++ ++ +    ++L I  L +E D   Y C      G
Sbjct: 70  VTDWAWYKITDSEDKALMNGSESRFFVSSSQGR-SELHIENLNMEADPGQYRCNGTSSKG 128

Query: 245 ESEEHIELVVLSYLVPLKPFLVIVAEVILLVATILLCEK 283
             +  I L V S+L  L PFL IVAEV++LV  I + EK
Sbjct: 129 SDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEK 167


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 52/207 (25%), Positives = 81/207 (39%), Gaps = 22/207 (10%)

Query: 84   VNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMGSYSCF 143
            V+L CQ         V VTW KDG++L                    +   K  G+Y C 
Sbjct: 3661 VHLECQVDED---RKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCT 3717

Query: 144  FREEKEQRG---TFNFKVPELHGK--NKPLISYVGDSTVLTCKCQNCFPLNWTWYSSNGS 198
               E        T   + P    K  +   +   G+S  L CK +    +  TW+ +N  
Sbjct: 3718 ASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKE 3777

Query: 199  VKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVL--- 255
            +     V+M  Y +N    +E  L IT +  ED  SY C A+  +G      E+V+    
Sbjct: 3778 LSESNTVRM--YFVN----SEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPP 3831

Query: 256  SYLVPLKPFLVIVAEVILLVATILLCE 282
            S++  L+P     A+++     +L CE
Sbjct: 3832 SFIKTLEP-----ADIVRGTNALLQCE 3853



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 50/187 (26%), Positives = 76/187 (40%), Gaps = 26/187 (13%)

Query: 64   LTEHSSMPVEKNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTL 123
            L++HS  P  K+I LE           T +G L  ++VTWKKDG  +  +   +    T 
Sbjct: 5992 LSDHSVEP-GKSIILES----------TYTGTL-PISVTWKKDGFNITTSEKCNIV--TT 6037

Query: 124  YTQYRFTIINS--KQMGSYSCFFREE--KEQRGTF--NFKVPELHGKNKPLISYVGDSTV 177
                   I+NS  +  G YSC    E  ++  G      + P    + +PL + VGDS  
Sbjct: 6038 EKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVS 6097

Query: 178  LTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWC 237
            L C+      +  +WY   G  K+    +   Y  N    N   L   ++   D   Y C
Sbjct: 6098 LQCQVAGTPEITVSWY--KGDTKLRPTPEYRTYFTN----NVATLVFNKVNINDSGEYTC 6151

Query: 238  RALFQLG 244
            +A   +G
Sbjct: 6152 KAENSIG 6158



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 41/207 (19%), Positives = 81/207 (39%), Gaps = 30/207 (14%)

Query: 88   CQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMGSYSCFFREE 147
            C  +T      + + W K  ++L +      T   L +     ++ +   G+Y+C     
Sbjct: 4224 CLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNV 4283

Query: 148  K-----------EQRGTFNFKVPELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSSN 196
                        ++  TF  K+       K      GD+T L CK     P+  TW++++
Sbjct: 4284 AGGVECSANLFVKEPATFVEKLEPSQLLKK------GDATQLACKVTGTPPIKITWFAND 4337

Query: 197  GSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVLS 256
              +K     + +K+ ++   +    L++T +  ED   Y C A  + G   +H   +V+ 
Sbjct: 4338 REIK-----ESSKHRMSFVESTAV-LRLTDVGIEDSGEYMCEAQNEAG--SDHCSSIVIV 4389

Query: 257  YLVP-----LKPFLVIVAEVILLVATI 278
               P      KP  V+    ++L+A +
Sbjct: 4390 KESPYFTKEFKPIEVLKEYDVMLLAEV 4416



 Score = 36.6 bits (83), Expect = 0.031
 Identities = 48/204 (23%), Positives = 76/204 (37%), Gaps = 36/204 (17%)

Query: 72   VEKNITLERPSNVNLTCQFT-----TSGDLNAVNVTWKKDGEQL--ENNYLVS----ATG 120
            +E    +E+P ++ +T   T     T      ++  W KDG++L  +N Y +S     +G
Sbjct: 7583 LEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSG 7642

Query: 121  STLYTQ-------YRFTIINSKQMGSYSCFFREEKEQRG---TFNFKVPELHGKNKPLIS 170
              +          Y F + N   +G  SC    +   R    +F  K+ E +G +     
Sbjct: 7643 LKIINVAPSDSGVYSFEVQNP--VGKDSCTASLQVSDRTVPPSFTRKLKETNGLS----- 7695

Query: 171  YVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEE 230
              G S V+ CK     P++ +W+     +         KY    T  N   L +  L E 
Sbjct: 7696 --GSSVVMECKVYGSPPISVSWFHEGNEIS-----SGRKYQTTLT-DNTCALTVNMLEES 7747

Query: 231  DGESYWCRALFQLGESEEHIELVV 254
            D   Y C A    G  E    L V
Sbjct: 7748 DSGDYTCIATNMAGSDECSAPLTV 7771



 Score = 35.8 bits (81), Expect = 0.053
 Identities = 34/167 (20%), Positives = 64/167 (38%), Gaps = 12/167 (7%)

Query: 99   VNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMGSYSCFFREEKEQRGTFNFKV 158
            ++VTWKK+G  +  +   + T +             +  G Y+C+  E    + + + ++
Sbjct: 7897 ISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYI-ENASGKDSCSAQI 7955

Query: 159  -----PELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVIN 213
                 P    + +P+   VGDS  L C+      +  +WY  +  ++     +M+     
Sbjct: 7956 LILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMH----- 8010

Query: 214  GTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVLSYLVP 260
                N   L   Q+   D   Y C+A   +GE      L V    +P
Sbjct: 8011 -FRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLP 8056



 Score = 35.0 bits (79), Expect = 0.091
 Identities = 34/170 (20%), Positives = 66/170 (38%), Gaps = 15/170 (8%)

Query: 99   VNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMGSYSCFFREEKEQRGTFNFKV 158
            ++V+W KDG+ L+++  V  +             +    G YSC          + + ++
Sbjct: 8086 ISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASS-SARL 8144

Query: 159  PELHGKNKPLI--------SYVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKY 210
                GKN P          + VG+S    C      P+  +W   +  ++        KY
Sbjct: 8145 ILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIR-----SGGKY 8199

Query: 211  VINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVLSYLVP 260
             I+    N   L + ++ + D   Y C A+ ++G+     +L +   L+P
Sbjct: 8200 QIS-YLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIP 8248



 Score = 33.1 bits (74), Expect = 0.35
 Identities = 42/219 (19%), Positives = 81/219 (36%), Gaps = 23/219 (10%)

Query: 52   ANNFSLESHNISLTEHSSMPV---EKNITLERP--------SNVNLTCQFTTSGDLNAVN 100
            + +++ E+HN + +  SS  +   E  I  ++P        ++V+L C+   +   +   
Sbjct: 7373 SGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFH--- 7429

Query: 101  VTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMGSYSCFFREEKEQR---GTFNFK 157
            V+W KD  +L +            T      +++  +G Y C    +       G+   K
Sbjct: 7430 VSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALK 7489

Query: 158  VPELHGKNKPLIS-YVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTY 216
             P    K    IS  VG    L    +   P++  W+   G +     V+ +  +     
Sbjct: 7490 APPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEI-----VRESDNIWISYS 7544

Query: 217  ANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVL 255
             N   L+ +++   +   Y C+     G  E    L VL
Sbjct: 7545 ENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVL 7583



 Score = 32.3 bits (72), Expect = 0.59
 Identities = 33/184 (17%), Positives = 66/184 (35%), Gaps = 18/184 (9%)

Query: 64   LTEHSSMPVEKNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTL 123
            L +  +  VEK  +++      +T +   +G    + V W KDG+Q+  +   S +    
Sbjct: 5136 LVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPE-LKVKWLKDGKQIVPSRYFSMSFENN 5194

Query: 124  YTQYRFTIINSKQMGSYSCFFREEKE---------QRGTFNFKVPELHGKNKPLISYVGD 174
               +R   +  +  G Y+  F+ E +          R       P    K   +   +G 
Sbjct: 5195 VASFRIQSVMKQDSGQYT--FKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGS 5252

Query: 175  STVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGES 234
            S  + CK     P++  W+     +      ++        +     L++  L  ED  +
Sbjct: 5253 SIHMECKVSGSLPISAQWFKDGKEISTSAKYRL------VCHERSVSLEVNNLELEDTAN 5306

Query: 235  YWCR 238
            Y C+
Sbjct: 5307 YTCK 5310



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 27/122 (22%), Positives = 44/122 (36%), Gaps = 7/122 (5%)

Query: 82   SNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMGSYS 141
            S+V L C+ + +     V   W KD +Q+ N+     T     T      + +  +G Y 
Sbjct: 6473 SDVILQCEISGTPPFEVV---WVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYH 6529

Query: 142  CFFREEKEQ---RGTFNFKVPELHGKN-KPLISYVGDSTVLTCKCQNCFPLNWTWYSSNG 197
            C    E        +  FK P    K      + +GD+  L    +   P++  W    G
Sbjct: 6530 CKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRG 6589

Query: 198  SV 199
             V
Sbjct: 6590 EV 6591



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 38/180 (21%), Positives = 59/180 (32%), Gaps = 22/180 (12%)

Query: 83   NVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMGSYSC 142
            +V+L CQ   + +   + V+W K   +L          +       F  +N    G Y+C
Sbjct: 6095 SVSLQCQVAGTPE---ITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTC 6151

Query: 143  FFREEKEQRGTFNFKV----------PELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTW 192
               + +   GT + K           P    + K +   VG    LTC+     P+   W
Sbjct: 6152 ---KAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCW 6208

Query: 193  YSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIEL 252
            Y     ++    +Q           N   LKI Q        Y C A   LG +     L
Sbjct: 6209 YRDGVLLRDDENLQ------TSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARL 6262



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 38/182 (20%), Positives = 66/182 (36%), Gaps = 14/182 (7%)

Query: 94   GDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMGSYSCFFREE----KE 149
            G    + + W KD ++L +    S       T        +   G+Y C    +      
Sbjct: 4792 GGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATS 4851

Query: 150  QRGTFNFKVPELHGKNKP-LISYVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMN 208
            +   F  + P+   K  P L+   G ST   C+      +  +WY     +       + 
Sbjct: 4852 KATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEI-----TAIQ 4906

Query: 209  KYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVL---SYLVPLKPFL 265
            K+ I+      T  +I+    E+  +Y C A    G +   IEL V    +++  LKP  
Sbjct: 4907 KHGISFIDGLAT-FQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVE 4965

Query: 266  VI 267
            V+
Sbjct: 4966 VV 4967



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 39/176 (22%), Positives = 64/176 (36%), Gaps = 11/176 (6%)

Query: 89   QFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMGSYSCFFREEK 148
            Q T  G L  + VTW KD +++  +  +  T          + I  K  G Y C  + + 
Sbjct: 4506 QATLKGSL-PITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDA 4564

Query: 149  E-QRGTFNFKVPELHGKNKPLISY---VGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVG 204
              QR +    V E     +  +S     GD   L  K      +   W+     + +   
Sbjct: 4565 GIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLG-- 4622

Query: 205  VQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVLSYLVP 260
               +KY I+ T    + LKI    ++D   Y       +G S     + VL  ++P
Sbjct: 4623 ---SKYKISVT-DTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIP 4674



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 46/237 (19%), Positives = 79/237 (33%), Gaps = 20/237 (8%)

Query: 82   SNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMGSYS 141
            + V+L C+ + +     V   W KD  QL ++          +T      +++  +G Y 
Sbjct: 5532 AEVSLECELSGTPPFEVV---WYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYH 5588

Query: 142  CFFREEKEQRG---TFNFK-VPELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSSNG 197
            C  + E        T   K  P    K   L    G+   L    +   P+   W     
Sbjct: 5589 CKAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKE 5648

Query: 198  SVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVLSY 257
             V     ++ ++ +      N   L+  +    +   Y C+     G  E    L+VL  
Sbjct: 5649 EV-----IRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEP 5703

Query: 258  LVPLK---PFLVIVAEVILLVATI-----LLCEKYTQKKKKHSDEGKEFEQIEQLKS 306
             V ++   P  V V E   L   +     L  E Y   K   S +  +F    ++ S
Sbjct: 5704 AVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISS 5760



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 29/124 (23%), Positives = 43/124 (34%), Gaps = 16/124 (12%)

Query: 86   LTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMGSYSCFFR 145
            L C  T + +L+A    W KDG +L  +     T        +         G YS    
Sbjct: 6664 LECVVTGTPELSA---KWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSF--- 6717

Query: 146  EEKEQRGTFNFKV----------PELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSS 195
            E K   G  N  V          P    K K + + +G S VL C+     P++  W+  
Sbjct: 6718 EVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQD 6777

Query: 196  NGSV 199
               +
Sbjct: 6778 GNEI 6781



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 27/100 (27%), Positives = 40/100 (40%), Gaps = 23/100 (23%)

Query: 62    ISLTEHSSMPVEK--NITLERPSNVN-------------LTCQFTTSGDLNAVNVTWKKD 106
             +S TE    P EK  ++ +  P  +              LTC    S  L A  VTW KD
Sbjct: 32696 VSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTC-VVESSVLRAKEVTWYKD 32754

Query: 107   GEQLENN----YLVSATGSTLYTQYRFTIINSKQMGSYSC 142
             G++L+ N    +  SA G+    + +   +     G Y C
Sbjct: 32755 GKKLKENGHFQFHYSADGT---YELKINNLTESDQGEYVC 32791



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 5/63 (7%)

Query: 191   TWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHI 250
             TWY     +K     Q + Y  +GTY    +LKI  L E D   Y C    + G S+ ++
Sbjct: 32750 TWYKDGKKLKENGHFQFH-YSADGTY----ELKINNLTESDQGEYVCEISGEGGTSKTNL 32804

Query: 251   ELV 253
             + +
Sbjct: 32805 QFM 32807


>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
          Length = 1215

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 37/160 (23%), Positives = 69/160 (43%), Gaps = 20/160 (12%)

Query: 100 NVTWKKDGEQLENNYLVSATGS-TLYTQYRFTIINSKQMGSYSCFFREE----KEQRGTF 154
           +++W ++ + L+ +  +      TL  Q     +  +  G+YSC    E    +E    +
Sbjct: 521 HISWSRESQALQEDSRIHVDAQGTLIIQG----VAPEDAGNYSCQATNEVGTDQETVTLY 576

Query: 155 NFKVPELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVING 214
               P +   N  ++  VG+  VL C+     P    WY          G++M   ++  
Sbjct: 577 YTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRG--------GLEM---ILAP 625

Query: 215 TYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVV 254
             ++  KL+I    E D  +Y CRA+ +LG++   I+L V
Sbjct: 626 EGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 665


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 37/160 (23%), Positives = 69/160 (43%), Gaps = 20/160 (12%)

Query: 100 NVTWKKDGEQLENNYLVSATGS-TLYTQYRFTIINSKQMGSYSCFFREE----KEQRGTF 154
           +++W ++ + L+ +  +      TL  Q     +  +  G+YSC    E    +E    +
Sbjct: 638 HISWSRESQALQEDSRIHVDAQGTLIIQG----VAPEDAGNYSCQATNEVGTDQETVTLY 693

Query: 155 NFKVPELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVING 214
               P +   N  ++  VG+  VL C+     P    WY          G++M   ++  
Sbjct: 694 YTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRG--------GLEM---ILAP 742

Query: 215 TYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVV 254
             ++  KL+I    E D  +Y CRA+ +LG++   I+L V
Sbjct: 743 EGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 782



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 47/192 (24%), Positives = 77/192 (40%), Gaps = 28/192 (14%)

Query: 79   ERPSNVNLTCQFTTSGDLNAVN-----VTWKKDGEQL--ENNYLVSATGSTLYTQYRFTI 131
            E P+ V++      + + NA       VTW++DG+ +  E    +   G +L+ +     
Sbjct: 2263 EPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERA--- 2319

Query: 132  INSKQMGSYSCFFREEKEQRGTFNFKV-----PELHGKNKPLISYVG---DSTVLTCKCQ 183
              +   G YSC   E    R    F++     PEL G   PL +          L C+  
Sbjct: 2320 -QAAHTGRYSCV-AENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAM 2377

Query: 184  NCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQL 243
               P    W+      + PV    + Y++ G +     LK+TQ  E+D   Y C A  + 
Sbjct: 2378 GIPPPAIRWFRG----EEPVSPGEDTYLLAGGWM----LKMTQTQEQDSGLYSCLASNEA 2429

Query: 244  GESEEHIELVVL 255
            GE+  +  + VL
Sbjct: 2430 GEARRNFSVEVL 2441



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 42/187 (22%), Positives = 73/187 (39%), Gaps = 23/187 (12%)

Query: 84   VNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQM---GSY 140
            V LTC  T +    +  + W KDG  +         G  ++   R   + S +    G Y
Sbjct: 1995 VRLTCNATGAP---SPTLMWLKDGNPVSP---AGTPGLQVFPGGRVLTLASARASDSGRY 2048

Query: 141  SCF----FREEKEQRGTFNFKVPELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSSN 196
            SC       E+++         P + G+   +     +S  L C+     P   +W+   
Sbjct: 2049 SCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDG 2108

Query: 197  GSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVLS 256
              ++   GV ++        A++  L++ +    D   Y C AL Q G SE+H  L V  
Sbjct: 2109 RPLEPRPGVHLS--------ADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNV-- 2158

Query: 257  YLVPLKP 263
            ++ P+ P
Sbjct: 2159 WVAPVFP 2165



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 36/141 (25%), Positives = 58/141 (41%), Gaps = 23/141 (16%)

Query: 135  KQMGSYSCFF----REEKEQRGTFNFKVPELHGKNKPLISYVGDSTVLTCKCQNCFPLNW 190
            +++G +S  F    REE+ + G   ++      +N P   Y        C      P + 
Sbjct: 2734 QKVGDFSAAFEILSREEEARGGVTEYREIV---ENNPAYLY--------CDTNAIPPPDL 2782

Query: 191  TWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHI 250
            TWY  +     P+       V+ G       L+I  +  E+   Y C+A  ++GE   H 
Sbjct: 2783 TWYREDQ----PLSAGDEVSVLQGGRV----LQIPLVRAENAGRYSCKASNEVGEDWLHY 2834

Query: 251  ELVVLSYLVPLKPFLVIVAEV 271
            EL+VL+  V L     +V EV
Sbjct: 2835 ELLVLTPPVILGDTEELVEEV 2855



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 38/168 (22%), Positives = 63/168 (37%), Gaps = 27/168 (16%)

Query: 101  VTWKKDGEQLENN--YLVSATGSTLYTQYRFTIINSKQMGSYSCFFREEKEQRGTFNFKV 158
            +TW KDG  L     + +S  G  L         N    G YSC       ++ T +F++
Sbjct: 2477 LTWFKDGRPLARGDAHHISPDGVLLQVLQA----NLSSAGHYSCIAANAVGEK-TKHFQL 2531

Query: 159  PEL----------HGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMN 208
              L             ++ +   V +   L C+       N TW         P     N
Sbjct: 2532 SVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGA----PFEASRN 2587

Query: 209  KYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEE--HIELVV 254
              ++ GT+     L+I    +ED   Y C    +LGE+ +  H+E+++
Sbjct: 2588 IQLLPGTHG----LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLI 2631



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 41/196 (20%), Positives = 70/196 (35%), Gaps = 32/196 (16%)

Query: 73   EKNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTII 132
            E  +T+  P  ++L C+        + N+TW KDG   E +  +     T    +   I+
Sbjct: 2550 EVTVTVNNP--ISLICEALA---FPSPNITWMKDGAPFEASRNIQLLPGT----HGLQIL 2600

Query: 133  NSKQ--MGSYSCFFREEKEQRGTFNFKV----PELHGKNKPL--------ISYVGDSTVL 178
            N+++   G Y+C    E  +    N+ V    P    K+ PL         + V  +  L
Sbjct: 2601 NAQKEDAGQYTCVVTNELGE-AVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTL 2659

Query: 179  TCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCR 238
             C+     P    WY     V     +Q+              L+I      D   Y C 
Sbjct: 2660 ECESWAVPPPTIRWYKDGQPVTPSSRLQV--------LGEGRLLQIQPTQVSDSGRYLCV 2711

Query: 239  ALFQLGESEEHIELVV 254
            A    GE ++   +++
Sbjct: 2712 ATNVAGEDDQDFNVLI 2727


>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
           sapiens]
          Length = 790

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 37/160 (23%), Positives = 69/160 (43%), Gaps = 20/160 (12%)

Query: 100 NVTWKKDGEQLENNYLVSATGS-TLYTQYRFTIINSKQMGSYSCFFREE----KEQRGTF 154
           +++W ++ + L+ +  +      TL  Q     +  +  G+YSC    E    +E    +
Sbjct: 637 HISWSRESQALQEDSRIHVDAQGTLIIQG----VAPEDAGNYSCQATNEVGTDQETVTLY 692

Query: 155 NFKVPELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVING 214
               P +   N  ++  VG+  VL C+     P    WY          G++M   ++  
Sbjct: 693 YTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRG--------GLEM---ILAP 741

Query: 215 TYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVV 254
             ++  KL+I    E D  +Y CRA+ +LG++   I+L V
Sbjct: 742 EGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 781


>gi|157168355 CD22 molecule [Homo sapiens]
          Length = 847

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 39/184 (21%), Positives = 73/184 (39%), Gaps = 35/184 (19%)

Query: 82  SNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMGSYS 141
           ++V+L C F++S     V   W+K+G  L              +Q  F  I+ +  GSYS
Sbjct: 523 NSVSLQCDFSSSHP-KEVQFFWEKNGRLLGKE-----------SQLNFDSISPEDAGSYS 570

Query: 142 CFFREEKEQRGTFNFKVPELHGKNKPLISYV-------GDSTVLTCKCQNCFPLN-WTWY 193
           C+      Q  +  + +  L+   +  +S         G S  LTC+     P++ +TW+
Sbjct: 571 CWVNNSIGQTASKAWTLEVLYAPRRLRVSMSPGDQVMEGKSATLTCESDANPPVSHYTWF 630

Query: 194 SSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELV 253
             N    +P   Q              KL++  +  +   +YWC+    +G+    +  +
Sbjct: 631 DWNNQ-SLPYHSQ--------------KLRLEPVKVQHSGAYWCQGTNSVGKGRSPLSTL 675

Query: 254 VLSY 257
            + Y
Sbjct: 676 TVYY 679


>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
           precursor [Homo sapiens]
          Length = 2012

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 38/158 (24%), Positives = 65/158 (41%), Gaps = 11/158 (6%)

Query: 93  SGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMGSYSCFFREEK---E 149
           SGDL  + +TW+KDG  +  +  V+       +  R + ++    G+Y+C  R E    E
Sbjct: 621 SGDL-PITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVE 679

Query: 150 QRGTFNFKV-PELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMN 208
            +     +V P+   + +      G + +L C  +        W  S G+  VP   Q  
Sbjct: 680 HQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGA-GVP---QFQ 735

Query: 209 KYVING--TYANETKLKITQLLEEDGESYWCRALFQLG 244
              +NG     +   L I  ++EED   Y C+    +G
Sbjct: 736 PIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVG 773



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 4/67 (5%)

Query: 82  SNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMGSYS 141
           S V+L+C  T + D     ++W ++GE L     V  TG          ++ S   G+Y 
Sbjct: 329 SQVSLSCSVTGTEDQE---LSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDG-GAYQ 384

Query: 142 CFFREEK 148
           CF R++K
Sbjct: 385 CFVRKDK 391


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 47/192 (24%), Positives = 77/192 (40%), Gaps = 28/192 (14%)

Query: 79   ERPSNVNLTCQFTTSGDLNAVN-----VTWKKDGEQL--ENNYLVSATGSTLYTQYRFTI 131
            E P+ V++      + + NA       VTW++DG+ +  E    +   G +L+ +     
Sbjct: 1072 EPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERA--- 1128

Query: 132  INSKQMGSYSCFFREEKEQRGTFNFKV-----PELHGKNKPLISYVG---DSTVLTCKCQ 183
              +   G YSC   E    R    F++     PEL G   PL +          L C+  
Sbjct: 1129 -QAAHTGRYSCV-AENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAM 1186

Query: 184  NCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQL 243
               P    W+      + PV    + Y++ G +     LK+TQ  E+D   Y C A  + 
Sbjct: 1187 GIPPPAIRWFRG----EEPVSPGEDTYLLAGGWM----LKMTQTQEQDSGLYSCLASNEA 1238

Query: 244  GESEEHIELVVL 255
            GE+  +  + VL
Sbjct: 1239 GEARRNFSVEVL 1250



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 42/187 (22%), Positives = 73/187 (39%), Gaps = 23/187 (12%)

Query: 84  VNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQM---GSY 140
           V LTC  T +    +  + W KDG  +         G  ++   R   + S +    G Y
Sbjct: 804 VRLTCNATGAP---SPTLMWLKDGNPVSP---AGTPGLQVFPGGRVLTLASARASDSGRY 857

Query: 141 SCF----FREEKEQRGTFNFKVPELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSSN 196
           SC       E+++         P + G+   +     +S  L C+     P   +W+   
Sbjct: 858 SCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDG 917

Query: 197 GSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVLS 256
             ++   GV ++        A++  L++ +    D   Y C AL Q G SE+H  L V  
Sbjct: 918 RPLEPRPGVHLS--------ADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNV-- 967

Query: 257 YLVPLKP 263
           ++ P+ P
Sbjct: 968 WVAPVFP 974



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 36/141 (25%), Positives = 58/141 (41%), Gaps = 23/141 (16%)

Query: 135  KQMGSYSCFF----REEKEQRGTFNFKVPELHGKNKPLISYVGDSTVLTCKCQNCFPLNW 190
            +++G +S  F    REE+ + G   ++      +N P   Y        C      P + 
Sbjct: 1543 QKVGDFSAAFEILSREEEARGGVTEYREIV---ENNPAYLY--------CDTNAIPPPDL 1591

Query: 191  TWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHI 250
            TWY  +     P+       V+ G       L+I  +  E+   Y C+A  ++GE   H 
Sbjct: 1592 TWYREDQ----PLSAGDEVSVLQGGRV----LQIPLVRAENAGRYSCKASNEVGEDWLHY 1643

Query: 251  ELVVLSYLVPLKPFLVIVAEV 271
            EL+VL+  V L     +V EV
Sbjct: 1644 ELLVLTPPVILGDTEELVEEV 1664



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 38/168 (22%), Positives = 63/168 (37%), Gaps = 27/168 (16%)

Query: 101  VTWKKDGEQLENN--YLVSATGSTLYTQYRFTIINSKQMGSYSCFFREEKEQRGTFNFKV 158
            +TW KDG  L     + +S  G  L         N    G YSC       ++ T +F++
Sbjct: 1286 LTWFKDGRPLARGDAHHISPDGVLLQVLQA----NLSSAGHYSCIAANAVGEK-TKHFQL 1340

Query: 159  PEL----------HGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMN 208
              L             ++ +   V +   L C+       N TW         P     N
Sbjct: 1341 SVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGA----PFEASRN 1396

Query: 209  KYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEE--HIELVV 254
              ++ GT+     L+I    +ED   Y C    +LGE+ +  H+E+++
Sbjct: 1397 IQLLPGTHG----LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLI 1440



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 41/196 (20%), Positives = 70/196 (35%), Gaps = 32/196 (16%)

Query: 73   EKNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTII 132
            E  +T+  P  ++L C+        + N+TW KDG   E +  +     T    +   I+
Sbjct: 1359 EVTVTVNNP--ISLICEALA---FPSPNITWMKDGAPFEASRNIQLLPGT----HGLQIL 1409

Query: 133  NSKQ--MGSYSCFFREEKEQRGTFNFKV----PELHGKNKPL--------ISYVGDSTVL 178
            N+++   G Y+C    E  +    N+ V    P    K+ PL         + V  +  L
Sbjct: 1410 NAQKEDAGQYTCVVTNELGE-AVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTL 1468

Query: 179  TCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCR 238
             C+     P    WY     V     +Q+              L+I      D   Y C 
Sbjct: 1469 ECESWAVPPPTIRWYKDGQPVTPSSRLQV--------LGEGRLLQIQPTQVSDSGRYLCV 1520

Query: 239  ALFQLGESEEHIELVV 254
            A    GE ++   +++
Sbjct: 1521 ATNVAGEDDQDFNVLI 1536


>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3783

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 47/192 (24%), Positives = 77/192 (40%), Gaps = 28/192 (14%)

Query: 79   ERPSNVNLTCQFTTSGDLNAVN-----VTWKKDGEQL--ENNYLVSATGSTLYTQYRFTI 131
            E P+ V++      + + NA       VTW++DG+ +  E    +   G +L+ +     
Sbjct: 981  EPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERA--- 1037

Query: 132  INSKQMGSYSCFFREEKEQRGTFNFKV-----PELHGKNKPLISYVG---DSTVLTCKCQ 183
              +   G YSC   E    R    F++     PEL G   PL +          L C+  
Sbjct: 1038 -QAAHTGRYSCV-AENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAM 1095

Query: 184  NCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQL 243
               P    W+      + PV    + Y++ G +     LK+TQ  E+D   Y C A  + 
Sbjct: 1096 GIPPPAIRWFRG----EEPVSPGEDTYLLAGGWM----LKMTQTQEQDSGLYSCLASNEA 1147

Query: 244  GESEEHIELVVL 255
            GE+  +  + VL
Sbjct: 1148 GEARRNFSVEVL 1159



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 42/187 (22%), Positives = 73/187 (39%), Gaps = 23/187 (12%)

Query: 84  VNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQM---GSY 140
           V LTC  T +    +  + W KDG  +         G  ++   R   + S +    G Y
Sbjct: 713 VRLTCNATGAP---SPTLMWLKDGNPVSP---AGTPGLQVFPGGRVLTLASARASDSGRY 766

Query: 141 SCF----FREEKEQRGTFNFKVPELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSSN 196
           SC       E+++         P + G+   +     +S  L C+     P   +W+   
Sbjct: 767 SCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDG 826

Query: 197 GSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVLS 256
             ++   GV ++        A++  L++ +    D   Y C AL Q G SE+H  L V  
Sbjct: 827 RPLEPRPGVHLS--------ADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNV-- 876

Query: 257 YLVPLKP 263
           ++ P+ P
Sbjct: 877 WVAPVFP 883



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 41/196 (20%), Positives = 70/196 (35%), Gaps = 32/196 (16%)

Query: 73   EKNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTII 132
            E  +T+  P  ++L C+        + N+TW KDG   E +  +     T    +   I+
Sbjct: 1268 EVTVTVNNP--ISLICEALA---FPSPNITWMKDGAPFEASRNIQLLPGT----HGLQIL 1318

Query: 133  NSKQ--MGSYSCFFREEKEQRGTFNFKV----PELHGKNKPLI--------SYVGDSTVL 178
            N+++   G Y+C    E  +    N+ V    P    K+ PL         + V  +  L
Sbjct: 1319 NAQKEDAGQYTCVVTNELGE-AVKNYHVEVLIPPSISKDDPLAEVGVKEVKTKVNSTLTL 1377

Query: 179  TCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCR 238
             C+     P    WY     V     +Q+              L+I      D   Y C 
Sbjct: 1378 ECESWAVPPPTIRWYKDGQPVTPSSRLQV--------LGEGRLLQIQPTQVSDSGRYLCV 1429

Query: 239  ALFQLGESEEHIELVV 254
            A    GE ++   +++
Sbjct: 1430 ATNVAGEDDQDFNVLI 1445



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 36/141 (25%), Positives = 58/141 (41%), Gaps = 23/141 (16%)

Query: 135  KQMGSYSCFF----REEKEQRGTFNFKVPELHGKNKPLISYVGDSTVLTCKCQNCFPLNW 190
            +++G +S  F    REE+ + G   ++      +N P   Y        C      P + 
Sbjct: 1452 QKVGDFSAAFEILSREEEARGGVTEYREIV---ENNPAYLY--------CDTNAIPPPDL 1500

Query: 191  TWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHI 250
            TWY  +     P+       V+ G       L+I  +  E+   Y C+A  ++GE   H 
Sbjct: 1501 TWYREDQ----PLSAGDEVSVLQGGRV----LQIPLVRAENAGRYSCKASNEVGEDWLHY 1552

Query: 251  ELVVLSYLVPLKPFLVIVAEV 271
            EL+VL+  V L     +V EV
Sbjct: 1553 ELLVLTPPVILGDTEELVEEV 1573



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 38/168 (22%), Positives = 63/168 (37%), Gaps = 27/168 (16%)

Query: 101  VTWKKDGEQLENN--YLVSATGSTLYTQYRFTIINSKQMGSYSCFFREEKEQRGTFNFKV 158
            +TW KDG  L     + +S  G  L         N    G YSC       ++ T +F++
Sbjct: 1195 LTWFKDGRPLARGDAHHISPDGVLLQVLQA----NLSSAGHYSCIAANAVGEK-TKHFQL 1249

Query: 159  PEL----------HGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMN 208
              L             ++ +   V +   L C+       N TW         P     N
Sbjct: 1250 SVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGA----PFEASRN 1305

Query: 209  KYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEE--HIELVV 254
              ++ GT+     L+I    +ED   Y C    +LGE+ +  H+E+++
Sbjct: 1306 IQLLPGTHG----LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLI 1349


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 43/197 (21%), Positives = 78/197 (39%), Gaps = 24/197 (12%)

Query: 74   KNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIIN 133
            +++ ++   +V LTC+ T +       +TW KDG+ L+ +          + Q   T + 
Sbjct: 2487 EDVKVKEKQSVTLTCEVTGNP---VPEITWHKDGQPLQEDEAHHIISGGRFLQ--ITNVQ 2541

Query: 134  SKQMGSYSCFFRE---EKEQRGTFN-FKVPEL-----HGKNKPLISYVGDSTVLTCKCQN 184
                G Y+C        K +  + N F  P +      G  + +   +   T L C+  +
Sbjct: 2542 VPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYS 2601

Query: 185  CFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLG 244
              P   TW+        P+    N  ++ G       L+I    E++   Y C A  + G
Sbjct: 2602 YPPATITWFKDG----TPLESNRNIRILPGGRT----LQILNAQEDNAGRYSCVATNEAG 2653

Query: 245  ESEEHIELVVLSYLVPL 261
            E  +H E+ V  Y+ P+
Sbjct: 2654 EMIKHYEVKV--YIPPI 2668



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 41/162 (25%), Positives = 72/162 (44%), Gaps = 23/162 (14%)

Query: 102  TWKKDGEQL--ENNYLVSATGSTLYTQYRFTIINSK--QMGSYSCFFREEK-EQRGTFNF 156
            +W+KDG+ L  ++++   + G  L       I+N++   +G Y C         +  FN 
Sbjct: 2905 SWQKDGQPLLEDDHHKFLSNGRILQ------ILNTQITDIGRYVCVAENTAGSAKKYFNL 2958

Query: 157  KV---PELHG-KNKPLISYVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVI 212
             V   P + G K++ L   V +   LTC+     P + +W  +    + P+ +  N  ++
Sbjct: 2959 NVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKN----EQPIKLNTNTLIV 3014

Query: 213  NGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVV 254
             G       L+I +    DG  Y C A+ Q GES++   L V
Sbjct: 3015 PGGRT----LQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 36/173 (20%), Positives = 71/173 (41%), Gaps = 22/173 (12%)

Query: 84   VNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQM---GSY 140
            V L C+   +  + A ++TW KDG  + +     + G  + +  R   + S Q+   G Y
Sbjct: 2029 VRLECE---ARGIPAPSLTWLKDGSPVSS----FSNGLQVLSGGRILALTSAQISDTGRY 2081

Query: 141  SCF-FREEKEQRGTFNFKV---PELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSSN 196
            +C       E++   + +V   P + G+ + +   +  +  L C+     P   TW    
Sbjct: 2082 TCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDG 2141

Query: 197  GSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEH 249
              +    G+ +++        N + LKI     +D   Y C A    G++E++
Sbjct: 2142 HPLLKKPGLSISE--------NRSVLKIEDAQVQDTGRYTCEATNVAGKTEKN 2186



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 52/217 (23%), Positives = 82/217 (37%), Gaps = 27/217 (12%)

Query: 74   KNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIIN 133
            ++IT+ R   V L C+   S  +    +TW ++GE+L+    V       Y Q     IN
Sbjct: 3629 RDITVLRNRQVTLECK---SDAVPPPVITWLRNGERLQATPRVRILSGGRYLQ-----IN 3680

Query: 134  SKQMG---SYSCFF-----REEKEQRGTFNFKVPELHGKNKPLISYVGDSTVLTCKCQNC 185
            +  +G   +Y+C       +  +E   T N   P + G  + L+  +  STVL C  +  
Sbjct: 3681 NADLGDTANYTCVASNIAGKTTREFILTVNVP-PNIKGGPQSLVILLNKSTVLECIAEGV 3739

Query: 186  FPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGE 245
                 TW        V  G      ++   + +     +T     D   Y C A    G 
Sbjct: 3740 PTPRITWRKDGA---VLAGNHARYSILENGFLHIQSAHVT-----DTGRYLCMATNAAGT 3791

Query: 246  SEEHIELVVLSYLVPLKPFLVIVAEVILLVATILLCE 282
                I+L V  ++ P          VI+ V T L CE
Sbjct: 3792 DRRRIDLQV--HVPPSIAPGPTNMTVIVNVQTTLACE 3826



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 31/124 (25%), Positives = 50/124 (40%), Gaps = 12/124 (9%)

Query: 135 KQMGSYSCFFREEK---EQRGTFNF-KVPELHGKNKPLISYVGDSTVLTCKCQNCFPLNW 190
           K  G Y C         +Q  T  + + P+L      L+  +GD TV+ CK     P   
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQV 733

Query: 191 TWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHI 250
            W+      K  + ++ + ++I        K++ TQ L  D   Y C A+ + G +   I
Sbjct: 734 KWF------KGDLELRPSTFLIIDPLLGLLKIQETQDL--DAGDYTCVAINEAGRATGKI 785

Query: 251 ELVV 254
            L V
Sbjct: 786 TLDV 789



 Score = 28.9 bits (63), Expect = 6.5
 Identities = 46/190 (24%), Positives = 72/190 (37%), Gaps = 33/190 (17%)

Query: 74   KNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLEN--NYLVSATGSTLYTQYRFTI 131
            +++T+   S  +L C+   +       +TW KDG  LE+  N  +   G TL       I
Sbjct: 2583 EDVTVILNSPTSLVCE---AYSYPPATITWFKDGTPLESNRNIRILPGGRTL------QI 2633

Query: 132  INSKQ--MGSYSCFFREEK-EQRGTFNFKV--PELHGKN---------KPLISYVGDSTV 177
            +N+++   G YSC    E  E    +  KV  P +  K          K +   V ++  
Sbjct: 2634 LNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLT 2693

Query: 178  LTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWC 237
            L C+       + +WY     +K    V +         AN   L+I +    D   Y C
Sbjct: 2694 LECEAYAIPSASLSWYKDGQPLKSDDHVNI--------AANGHTLQIKEAQISDTGRYTC 2745

Query: 238  RALFQLGESE 247
             A    GE E
Sbjct: 2746 VASNIAGEDE 2755



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 14/33 (42%), Positives = 20/33 (60%)

Query: 222  LKITQLLEEDGESYWCRALFQLGESEEHIELVV 254
            L+I + L ED   Y C A    GE+++HI+L V
Sbjct: 1883 LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915



 Score = 28.5 bits (62), Expect = 8.5
 Identities = 42/202 (20%), Positives = 77/202 (38%), Gaps = 37/202 (18%)

Query: 74   KNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQL--ENNYLVSATGSTLYTQYRFTI 131
            K + ++  + + L C+      + + +++W KDG+ L  +++  ++A G TL  +     
Sbjct: 2682 KEVKIKVNNTLTLECEAYA---IPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEA--- 2735

Query: 132  INSKQMGSYSCFFRE---EKEQRGTFNFKVPEL---------------HGKNKPLISYVG 173
                  G Y+C       E E     N +VP                 +G+ K +I  + 
Sbjct: 2736 -QISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVI--IN 2792

Query: 174  DSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGE 233
            +   L C+     P   TWY        P+       ++ G       L+I +   ED  
Sbjct: 2793 NPISLYCETNAAPPPTLTWYKDGH----PLTSSDKVLILPGGRV----LQIPRAKVEDAG 2844

Query: 234  SYWCRALFQLGESEEHIELVVL 255
             Y C A+ + GE     ++ VL
Sbjct: 2845 RYTCVAVNEAGEDSLQYDVRVL 2866


>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
           sapiens]
          Length = 848

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 44/194 (22%), Positives = 75/194 (38%), Gaps = 27/194 (13%)

Query: 75  NITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLE-----NNYLVSATGSTLYTQYRF 129
           N T     +V L C    +       ++W KDGEQ+E       Y+ S   S    Q   
Sbjct: 222 NATANLGQSVTLVCD---AEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSS----QLTI 274

Query: 130 TIINSKQMGSYSCFFREEK-EQRGTFNFKVPELHGKNKPLISYVGDST--------VLTC 180
             ++      Y C    +  EQ  T + KV       KP I+YV + T         LTC
Sbjct: 275 KKVDKNDEAEYICIAENKAGEQDATIHLKV-----FAKPKITYVENQTAMELEEQVTLTC 329

Query: 181 KCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRAL 240
           +       + TW +S  ++       ++ +++  ++A  + L +  +   D   Y C A 
Sbjct: 330 EASGDPIPSITWRTSTRNISSEEKT-LDGHMVVRSHARVSSLTLKSIQYTDAGEYICTAS 388

Query: 241 FQLGESEEHIELVV 254
             +G+  + + L V
Sbjct: 389 NTIGQDSQSMYLEV 402


>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
           sapiens]
          Length = 761

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 44/194 (22%), Positives = 75/194 (38%), Gaps = 27/194 (13%)

Query: 75  NITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLE-----NNYLVSATGSTLYTQYRF 129
           N T     +V L C    +       ++W KDGEQ+E       Y+ S   S    Q   
Sbjct: 222 NATANLGQSVTLVCD---AEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSS----QLTI 274

Query: 130 TIINSKQMGSYSCFFREEK-EQRGTFNFKVPELHGKNKPLISYVGDST--------VLTC 180
             ++      Y C    +  EQ  T + KV       KP I+YV + T         LTC
Sbjct: 275 KKVDKNDEAEYICIAENKAGEQDATIHLKV-----FAKPKITYVENQTAMELEEQVTLTC 329

Query: 181 KCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRAL 240
           +       + TW +S  ++       ++ +++  ++A  + L +  +   D   Y C A 
Sbjct: 330 EASGDPIPSITWRTSTRNISSEEKT-LDGHMVVRSHARVSSLTLKSIQYTDAGEYICTAS 388

Query: 241 FQLGESEEHIELVV 254
             +G+  + + L V
Sbjct: 389 NTIGQDSQSMYLEV 402


>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
           [Homo sapiens]
          Length = 1093

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 58/259 (22%), Positives = 92/259 (35%), Gaps = 34/259 (13%)

Query: 50  IMANNF-SLESHNISLTEH---SSMPVEKNITLERPSNVNLTCQFTTSGDLNAVNVTWKK 105
           ++ N+F S  SH   LT +   S      +IT+   +   L C  T  G  N   + W+K
Sbjct: 578 VITNHFGSTYSHKARLTVNVLPSFTKTPHDITIRTTTMARLECAAT--GHPNP-QIAWQK 634

Query: 106 DG-----EQLENNYLVSATGSTLYTQYRFTIINSKQMGSYSCFFREEK---EQRGTFN-F 156
           DG        E    V       +     T +     G YSC  +          T    
Sbjct: 635 DGGTDFPAARERRMHVMPDDDVFF----ITDVKIDDAGVYSCTAQNSAGSISANATLTVL 690

Query: 157 KVPELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTY 216
           + P L    +  +  VG++  L CK     P   TW+  +     P+ +    ++     
Sbjct: 691 ETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDR----PLSLTERHHLT---- 742

Query: 217 ANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVLSYLVPLKP------FLVIVAE 270
            +   L +  ++ ED   Y C     LG    H +L VL      K       F + V  
Sbjct: 743 PDNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLPAAGCRKDGTTVGIFTIAVVS 802

Query: 271 VILLVATILLCEKYTQKKK 289
            I+L + + +C  Y  +KK
Sbjct: 803 SIVLTSLVWVCIIYQTRKK 821


>gi|33519481 neural cell adhesion molecule 2 precursor [Homo
           sapiens]
          Length = 837

 Score = 37.7 bits (86), Expect = 0.014
 Identities = 33/143 (23%), Positives = 60/143 (41%), Gaps = 22/143 (15%)

Query: 132 INSKQMGSYSCFFREEKEQRGTFNFKVPELHGKNKPLISYV----------GDSTVLTCK 181
           IN    G Y C  R E   RG  +F+   +     P IS            G+    +C+
Sbjct: 176 INKSDEGIYRCEGRVEA--RGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCR 233

Query: 182 CQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALF 241
                    +W+ +   ++     +  KY++ G+    T+L +  ++  DG  Y CRA  
Sbjct: 234 ASGSPEPAISWFRNGKLIE-----ENEKYILKGS---NTELTVRNIINSDGGPYVCRATN 285

Query: 242 QLGESEEH--IELVVLSYLVPLK 262
           + GE E+   +++ V  +++ LK
Sbjct: 286 KAGEDEKQAFLQVFVQPHIIQLK 308


>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
            RhoGEF isoform a [Homo sapiens]
          Length = 6620

 Score = 37.4 bits (85), Expect = 0.018
 Identities = 60/253 (23%), Positives = 104/253 (41%), Gaps = 39/253 (15%)

Query: 49   EIMANNFSLESHNISLTEHSSMPVEKNI-TLERPSNVNLTCQFTTSGDLNA------VNV 101
            + +A  +S E+ +  L+ H  +   K +   E+P++  +  +  TS  L+         V
Sbjct: 1506 QAVAGEYSCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGTSATLSCEVAQAQTEV 1565

Query: 102  TWKKDGEQLENNYLV--SATGSTLYTQYRFTIINSKQ--MGSYSCFFREEKEQRGTFNFK 157
            TW KDG++L ++  V   A G T     R  +  + Q   G YSC   +  +QR +F+  
Sbjct: 1566 TWYKDGKKLSSSSKVRMEAVGCT----RRLVVQEAGQADAGEYSC---KAGDQRLSFHLH 1618

Query: 158  VPE---LHGKNKP----LISYVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKY 210
            V E   +  K +P    + +  G S  L+C+         TWY     +     V++   
Sbjct: 1619 VAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQA-QTEVTWYKDGKKLSSSSKVRVE-- 1675

Query: 211  VINGTYANETKLKITQLLEEDGESYWC-----RALFQLGESEEHIELVVLSYLVPLKPFL 265
                      +L + Q  + D   Y C     R  F+L  +E  +E  +       +P +
Sbjct: 1676 ----AVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLHVAE--LEPQISERPCRREPLV 1729

Query: 266  VIVAEVILLVATI 278
            V   E I+L AT+
Sbjct: 1730 VKEHEDIILTATL 1742



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 44/204 (21%), Positives = 75/204 (36%), Gaps = 26/204 (12%)

Query: 59   SHNISLTEHSSM-----PVEKNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENN 113
            S  + +TE   M      V   +  E  ++  L+C+   +       VTW KDG++L ++
Sbjct: 1062 SFRLHITEPKMMFAKEQSVHNEVQAEAGASAMLSCEVAQA----QTEVTWYKDGKKLSSS 1117

Query: 114  YLVSATGSTLYTQYRFTIINSKQMGSYSCFFREEKEQRGTFNFKVPELHG-------KNK 166
              V         +           G YSC   E   QR +F+  + E  G        + 
Sbjct: 1118 SKVGMEVKGCTRRLVLPQAGKADAGEYSC---EAGGQRVSFHLHITEPKGVFAKEQSVHN 1174

Query: 167  PLISYVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQ 226
             + +  G + +L+C+         TWY     +     V+M    + G      +L + Q
Sbjct: 1175 EVQAEAGTTAMLSCEVAQP-QTEVTWYKDGKKLSSSSKVRME---VKGC---TRRLVVQQ 1227

Query: 227  LLEEDGESYWCRALFQLGESEEHI 250
            + + D   Y C A  Q    + HI
Sbjct: 1228 VGKADAGEYSCEAGGQRVSFQLHI 1251



 Score = 32.3 bits (72), Expect = 0.59
 Identities = 36/175 (20%), Positives = 61/175 (34%), Gaps = 21/175 (12%)

Query: 72   VEKNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTI 131
            V   +  E  ++  L+C+   +       VTW KDG++L ++  V    +    Q     
Sbjct: 1264 VHNEVRTEAGASATLSCEVAQA----QTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQ 1319

Query: 132  INSKQMGSYSCFFREEKEQRGTFNFKVPELHG-------KNKPLISYVGDSTVLTCKCQN 184
                  G Y+C   E   QR +F+  V E           ++ + +  G    L+C+   
Sbjct: 1320 AGQADAGEYTC---EAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQ 1376

Query: 185  CFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRA 239
                  TWY     +     V+M             +L + Q  + D   Y C A
Sbjct: 1377 A-QTEVTWYKDGKKLSSSSKVRME------AVGCTRRLVVQQACQADTGEYSCEA 1424



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 46/188 (24%), Positives = 72/188 (38%), Gaps = 29/188 (15%)

Query: 74   KNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLV--SATGSTLYTQYRFTI 131
            + +  E  ++  L+C+   +       VTW KDG++L ++  V   ATG T     R  +
Sbjct: 898  RKLQAEAGASATLSCEVAQA----QTEVTWYKDGKKLSSSSKVCMEATGCT----RRLVV 949

Query: 132  INSKQ--MGSYSCFFREEKEQRGTFNFKVPE---LHGKNKPLISYV----GDSTVLTCKC 182
              + Q   G YSC   E   QR +F+  V E   +  K++   S V    G S  L+C+ 
Sbjct: 950  QQAGQADAGEYSC---EAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEV 1006

Query: 183  QNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQ 242
                     WY     +   + V +             +L + Q  + D   Y C A  Q
Sbjct: 1007 AQA-QTEVMWYKDGKKLSSSLKVHVE------AKGCRRRLVVQQAGKTDAGDYSCEARGQ 1059

Query: 243  LGESEEHI 250
                  HI
Sbjct: 1060 RVSFRLHI 1067



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 35/154 (22%), Positives = 58/154 (37%), Gaps = 21/154 (13%)

Query: 72   VEKNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTI 131
            V   +  E  +   L+C+           VTW KDG++L ++  V         +     
Sbjct: 1172 VHNEVQAEAGTTAMLSCEVAQP----QTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQ 1227

Query: 132  INSKQMGSYSCFFREEKEQRGTFNFKVPE---LHGKNKPLISYV----GDSTVLTCKCQN 184
            +     G YSC   E   QR +F   + E   +  K + + + V    G S  L+C+   
Sbjct: 1228 VGKADAGEYSC---EAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQ 1284

Query: 185  CFPLNWTWY------SSNGSVKVPVGVQMNKYVI 212
                  TWY      SS+  V++     M + V+
Sbjct: 1285 A-QTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVV 1317


>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
            RhoGEF isoform b [Homo sapiens]
          Length = 7968

 Score = 37.4 bits (85), Expect = 0.018
 Identities = 60/253 (23%), Positives = 104/253 (41%), Gaps = 39/253 (15%)

Query: 49   EIMANNFSLESHNISLTEHSSMPVEKNI-TLERPSNVNLTCQFTTSGDLNA------VNV 101
            + +A  +S E+ +  L+ H  +   K +   E+P++  +  +  TS  L+         V
Sbjct: 1506 QAVAGEYSCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGTSATLSCEVAQAQTEV 1565

Query: 102  TWKKDGEQLENNYLV--SATGSTLYTQYRFTIINSKQ--MGSYSCFFREEKEQRGTFNFK 157
            TW KDG++L ++  V   A G T     R  +  + Q   G YSC   +  +QR +F+  
Sbjct: 1566 TWYKDGKKLSSSSKVRMEAVGCT----RRLVVQEAGQADAGEYSC---KAGDQRLSFHLH 1618

Query: 158  VPE---LHGKNKP----LISYVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKY 210
            V E   +  K +P    + +  G S  L+C+         TWY     +     V++   
Sbjct: 1619 VAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQA-QTEVTWYKDGKKLSSSSKVRVE-- 1675

Query: 211  VINGTYANETKLKITQLLEEDGESYWC-----RALFQLGESEEHIELVVLSYLVPLKPFL 265
                      +L + Q  + D   Y C     R  F+L  +E  +E  +       +P +
Sbjct: 1676 ----AVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLHVAE--LEPQISERPCRREPLV 1729

Query: 266  VIVAEVILLVATI 278
            V   E I+L AT+
Sbjct: 1730 VKEHEDIILTATL 1742



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 44/204 (21%), Positives = 75/204 (36%), Gaps = 26/204 (12%)

Query: 59   SHNISLTEHSSM-----PVEKNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENN 113
            S  + +TE   M      V   +  E  ++  L+C+   +       VTW KDG++L ++
Sbjct: 1062 SFRLHITEPKMMFAKEQSVHNEVQAEAGASAMLSCEVAQA----QTEVTWYKDGKKLSSS 1117

Query: 114  YLVSATGSTLYTQYRFTIINSKQMGSYSCFFREEKEQRGTFNFKVPELHG-------KNK 166
              V         +           G YSC   E   QR +F+  + E  G        + 
Sbjct: 1118 SKVGMEVKGCTRRLVLPQAGKADAGEYSC---EAGGQRVSFHLHITEPKGVFAKEQSVHN 1174

Query: 167  PLISYVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQ 226
             + +  G + +L+C+         TWY     +     V+M    + G      +L + Q
Sbjct: 1175 EVQAEAGTTAMLSCEVAQP-QTEVTWYKDGKKLSSSSKVRME---VKGC---TRRLVVQQ 1227

Query: 227  LLEEDGESYWCRALFQLGESEEHI 250
            + + D   Y C A  Q    + HI
Sbjct: 1228 VGKADAGEYSCEAGGQRVSFQLHI 1251



 Score = 32.3 bits (72), Expect = 0.59
 Identities = 36/175 (20%), Positives = 61/175 (34%), Gaps = 21/175 (12%)

Query: 72   VEKNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTI 131
            V   +  E  ++  L+C+   +       VTW KDG++L ++  V    +    Q     
Sbjct: 1264 VHNEVRTEAGASATLSCEVAQA----QTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQ 1319

Query: 132  INSKQMGSYSCFFREEKEQRGTFNFKVPELHG-------KNKPLISYVGDSTVLTCKCQN 184
                  G Y+C   E   QR +F+  V E           ++ + +  G    L+C+   
Sbjct: 1320 AGQADAGEYTC---EAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQ 1376

Query: 185  CFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRA 239
                  TWY     +     V+M             +L + Q  + D   Y C A
Sbjct: 1377 A-QTEVTWYKDGKKLSSSSKVRME------AVGCTRRLVVQQACQADTGEYSCEA 1424



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 46/188 (24%), Positives = 72/188 (38%), Gaps = 29/188 (15%)

Query: 74   KNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLV--SATGSTLYTQYRFTI 131
            + +  E  ++  L+C+   +       VTW KDG++L ++  V   ATG T     R  +
Sbjct: 898  RKLQAEAGASATLSCEVAQA----QTEVTWYKDGKKLSSSSKVCMEATGCT----RRLVV 949

Query: 132  INSKQ--MGSYSCFFREEKEQRGTFNFKVPE---LHGKNKPLISYV----GDSTVLTCKC 182
              + Q   G YSC   E   QR +F+  V E   +  K++   S V    G S  L+C+ 
Sbjct: 950  QQAGQADAGEYSC---EAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEV 1006

Query: 183  QNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQ 242
                     WY     +   + V +             +L + Q  + D   Y C A  Q
Sbjct: 1007 AQA-QTEVMWYKDGKKLSSSLKVHVE------AKGCRRRLVVQQAGKTDAGDYSCEARGQ 1059

Query: 243  LGESEEHI 250
                  HI
Sbjct: 1060 RVSFRLHI 1067



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 6/62 (9%)

Query: 83   NVNLTCQFTTSGDLNAVNVTWKKDGEQLENN--YLVSATGSTLYTQYRFTIINSKQMGSY 140
            +V L CQ +      A   TW KDG  LE++   L+SAT    +      ++ ++ +G Y
Sbjct: 7479 SVTLACQVSAQP---AAQATWSKDGAPLESSSRVLISATLKN-FQLLTILVVVAEDLGVY 7534

Query: 141  SC 142
            +C
Sbjct: 7535 TC 7536



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 35/154 (22%), Positives = 58/154 (37%), Gaps = 21/154 (13%)

Query: 72   VEKNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTI 131
            V   +  E  +   L+C+           VTW KDG++L ++  V         +     
Sbjct: 1172 VHNEVQAEAGTTAMLSCEVAQP----QTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQ 1227

Query: 132  INSKQMGSYSCFFREEKEQRGTFNFKVPE---LHGKNKPLISYV----GDSTVLTCKCQN 184
            +     G YSC   E   QR +F   + E   +  K + + + V    G S  L+C+   
Sbjct: 1228 VGKADAGEYSC---EAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQ 1284

Query: 185  CFPLNWTWY------SSNGSVKVPVGVQMNKYVI 212
                  TWY      SS+  V++     M + V+
Sbjct: 1285 A-QTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVV 1317


>gi|4507875 vascular cell adhesion molecule 1 isoform a precursor
           [Homo sapiens]
          Length = 739

 Score = 36.2 bits (82), Expect = 0.041
 Identities = 45/202 (22%), Positives = 84/202 (41%), Gaps = 32/202 (15%)

Query: 66  EHSSMPVEKNITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYT 125
           +++ + V  +  L+   +V +TC   +S  L A  + W K   +L+N  L   +G+   T
Sbjct: 224 KNTVISVNPSTKLQEGGSVTMTC---SSEGLPAPEIFWSK---KLDNGNLQHLSGNATLT 277

Query: 126 QYRFTIINSKQMGSYSCFFREEKEQRGTFNFKVPELHGKNKP----------LISYVGDS 175
                + +S   G Y C    E       N K  EL  + KP          + + +GDS
Sbjct: 278 LIAMRMEDS---GIYVC----EGVNLIGKNRKEVELIVQEKPFTVEISPGPRIAAQIGDS 330

Query: 176 TVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESY 235
            +LTC    C   +++W +    +  P+  ++     N T      L ++ +  E+  SY
Sbjct: 331 VMLTCSVMGCESPSFSWRT---QIDSPLSGKVRSEGTNST------LTLSPVSFENEHSY 381

Query: 236 WCRALFQLGESEEHIELVVLSY 257
            C       + E+ I++ + S+
Sbjct: 382 LCTVTCGHKKLEKGIQVELYSF 403


>gi|166295173 kin of IRRE like [Homo sapiens]
          Length = 757

 Score = 36.2 bits (82), Expect = 0.041
 Identities = 45/205 (21%), Positives = 76/205 (37%), Gaps = 40/205 (19%)

Query: 61  NISLTEHSSMPVEKNI---TLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVS 117
           +I L  H    V  +I   T++    V  TCQ T + ++  +   W K G  +E+ +   
Sbjct: 214 SIELDVHHPPTVTLSIEPQTVQEGERVVFTCQATANPEI--LGYRWAKGGFLIEDAH--- 268

Query: 118 ATGSTLYTQYRFTIINSKQMGSYSCFFREEKEQRGTFNFKV-------PELHGKNKPLIS 170
                  ++Y   +  S      SC   E   + G+ N          P +    KP  +
Sbjct: 269 ------ESRYETNVDYSFFTEPVSC---EVHNKVGSTNVSTLVNVHFAPRIVVDPKPTTT 319

Query: 171 YVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQMNKYVINGTYANETKLKITQLLEE 230
            +G    LTC      PL  TW   +                N   +N  +L +  + + 
Sbjct: 320 DIGSDVTLTCVWVGNPPLTLTWTKKDS---------------NMVLSNSNQLLLKSVTQA 364

Query: 231 DGESYWCRALF-QLGESEEHIELVV 254
           D  +Y CRA+  ++G +E  + L V
Sbjct: 365 DAGTYTCRAIVPRIGVAEREVPLYV 389


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score = 35.8 bits (81), Expect = 0.053
 Identities = 53/239 (22%), Positives = 93/239 (38%), Gaps = 40/239 (16%)

Query: 28   RPSSADGSAPDSPFTSPPLREEIMANNFSLESHNISLTEHSSMPVEKNITLERPSNVNLT 87
            R +S  G   ++ FT      E   +++ L S  IS+   SS       T+++  + +  
Sbjct: 2992 RAASGPGPEQEASFTVTVPPSE--GSSYRLRSPVISIDPPSS-------TVQQGQDASFK 3042

Query: 88   CQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSK--QMGSYSCFFR 145
            C          +++ WK   ++LE+N  +S  GS +      TI+ ++    G+Y C   
Sbjct: 3043 CLIHDGAA--PISLEWKTRNQELEDNVHISPNGSII------TIVGTRPSNHGTYRCVAS 3094

Query: 146  EE-KEQRGTFNFKVPELHG-------KNKPLISYVGDSTVLTCKC--QNCFPLNWTWYSS 195
                  +   N  V   HG          P+   VG +  L C    +      WT  SS
Sbjct: 3095 NAYGVAQSVVNLSV---HGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISS 3151

Query: 196  NGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVV 254
                  P  ++   Y   G   +   L+I+     D  +Y C A   LG +++ +E++V
Sbjct: 3152 -----TPAKLEQRTY---GLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEVIV 3202


>gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo
           sapiens]
          Length = 858

 Score = 35.8 bits (81), Expect = 0.053
 Identities = 44/203 (21%), Positives = 75/203 (36%), Gaps = 35/203 (17%)

Query: 75  NITLERPSNVNLTCQFTTSGDLNAVNVTWKKDGEQLE-----NNYLVSATGSTLYTQYRF 129
           N T     +V L C    +       ++W KDGEQ+E       Y+ S   S    Q   
Sbjct: 222 NATANLGQSVTLVCD---AEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSS----QLTI 274

Query: 130 TIINSKQMGSYSCFFREEK-EQRGTFNFKVPELHGKNKPLISYVGDST--------VLTC 180
             ++      Y C    +  EQ  T + KV       KP I+YV + T         LTC
Sbjct: 275 KKVDKNDEAEYICIAENKAGEQDATIHLKV-----FAKPKITYVENQTAMELEEQVTLTC 329

Query: 181 KCQNCFPLNWTWYSSNGSVKVPVGVQ---------MNKYVINGTYANETKLKITQLLEED 231
           +       + TW +S  ++                ++ +++  ++A  + L +  +   D
Sbjct: 330 EASGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTD 389

Query: 232 GESYWCRALFQLGESEEHIELVV 254
              Y C A   +G+  + + L V
Sbjct: 390 AGEYICTASNTIGQDSQSMYLEV 412


>gi|7657361 contactin 6 [Homo sapiens]
          Length = 1028

 Score = 35.8 bits (81), Expect = 0.053
 Identities = 53/202 (26%), Positives = 73/202 (36%), Gaps = 28/202 (13%)

Query: 85  NLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMGSYSCFF 144
           NL  +   SG  N    TW K+GE+L     +     TL      T++N    G Y C  
Sbjct: 334 NLLWECKASGKPNPW-YTWLKNGERLNPEERIQIENGTLI----ITMLNVSDSGVYQCA- 387

Query: 145 REEKEQRGTFNFKVPELHG---------KNKPLISYVGDSTVLTCKCQNCFPLNWTWYSS 195
            E K Q    N ++  L           K K  +  VG   V+ CK  N FP        
Sbjct: 388 AENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQ-VGGDIVIGCK-PNAFP-------- 437

Query: 196 NGSVKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVL 255
             ++    G +  +         +  LKI  +   D  SY C A  Q G ++    L+V 
Sbjct: 438 RAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVK 497

Query: 256 S---YLVPLKPFLVIVAEVILL 274
                 VP     V V E I+L
Sbjct: 498 ERTVITVPPSKMDVTVGESIVL 519


>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
           sapiens]
          Length = 2113

 Score = 35.0 bits (79), Expect = 0.091
 Identities = 34/154 (22%), Positives = 59/154 (38%), Gaps = 10/154 (6%)

Query: 92  TSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYTQYRFTIINSKQMGSYSCFFREE---- 147
           +SGD+  + +TW+KDG+ + +   V+       +  + + ++ K  G+Y+C         
Sbjct: 680 SSGDM-PIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATV 738

Query: 148 KEQRGTFNFKVPELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSSNGSVKVPVGVQM 207
             +R       P    +        G + VL C      P    W  + GS       Q 
Sbjct: 739 SRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQ---QY 795

Query: 208 NKYVING--TYANETKLKITQLLEEDGESYWCRA 239
           +   + G       + L I  +LEED   Y C+A
Sbjct: 796 HPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQA 829


>gi|9624969 butyrophilin-like 2 [Homo sapiens]
          Length = 455

 Score = 34.7 bits (78), Expect = 0.12
 Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 17/92 (18%)

Query: 163 GKNKPLISYVGDSTVLTCKC---QNCFPLNWTWYSSNGSVKVPVG--------VQMNKY- 210
           G   P+++ VG+  +LTC+    +    +   WY S  S  V V         +QM +Y 
Sbjct: 33  GPAHPILAGVGEDALLTCQLLPKRTTMHVEVRWYRSEPSTPVFVHRDGVEVTEMQMEEYR 92

Query: 211 -----VINGTYANETKLKITQLLEEDGESYWC 237
                + NG       LKI  +   D   YWC
Sbjct: 93  GWVEWIENGIAKGNVALKIHNIQPSDNGQYWC 124


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,754,073
Number of Sequences: 37866
Number of extensions: 580251
Number of successful extensions: 2427
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 2133
Number of HSP's gapped (non-prelim): 330
length of query: 327
length of database: 18,247,518
effective HSP length: 103
effective length of query: 224
effective length of database: 14,347,320
effective search space: 3213799680
effective search space used: 3213799680
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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