BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|34452681 ring finger protein 10 [Homo sapiens] (811 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|34452681 ring finger protein 10 [Homo sapiens] 1637 0.0 gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo s... 50 8e-06 gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo s... 50 8e-06 gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s... 48 3e-05 gi|21071052 helicase-like transcription factor [Homo sapiens] 48 3e-05 gi|21071054 helicase-like transcription factor [Homo sapiens] 48 3e-05 gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens] 46 1e-04 gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens] 46 1e-04 gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens] 46 1e-04 gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens] 46 1e-04 gi|237858656 ring finger protein 170 isoform b [Homo sapiens] 45 3e-04 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 45 3e-04 gi|237858658 ring finger protein 170 isoform c [Homo sapiens] 45 4e-04 gi|237858654 ring finger protein 170 isoform a [Homo sapiens] 45 4e-04 gi|237858650 ring finger protein 170 isoform a [Homo sapiens] 45 4e-04 gi|56605981 tripartite motif-containing 72 [Homo sapiens] 45 4e-04 gi|5902054 ring finger protein 5 [Homo sapiens] 43 0.001 gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H... 43 0.001 gi|33356174 pinin, desmosome associated protein [Homo sapiens] 43 0.001 gi|209529681 ring finger protein 185 isoform 1 [Homo sapiens] 43 0.001 gi|31542783 ring finger protein 185 isoform 1 [Homo sapiens] 43 0.001 gi|24797089 peroxisome biogenesis factor 10 isoform 1 [Homo sapi... 42 0.002 gi|4505715 peroxisome biogenesis factor 10 isoform 2 [Homo sapiens] 42 0.002 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 42 0.002 gi|153791360 ret finger protein-like 4B [Homo sapiens] 42 0.002 gi|121114298 cullin 4B isoform 1 [Homo sapiens] 41 0.004 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 40 0.007 gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 40 0.007 gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor... 40 0.007 gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 40 0.009 >gi|34452681 ring finger protein 10 [Homo sapiens] Length = 811 Score = 1637 bits (4238), Expect = 0.0 Identities = 811/811 (100%), Positives = 811/811 (100%) Query: 1 MPLSSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGS 60 MPLSSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGS Sbjct: 1 MPLSSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGS 60 Query: 61 KRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEVA 120 KRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEVA Sbjct: 61 KRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEVA 120 Query: 121 EAQRAEFSPAQFSGPKKINLNHLLNFTFEPRGQTGHFEGSGHGSWGKRNKWGHKPFNKEL 180 EAQRAEFSPAQFSGPKKINLNHLLNFTFEPRGQTGHFEGSGHGSWGKRNKWGHKPFNKEL Sbjct: 121 EAQRAEFSPAQFSGPKKINLNHLLNFTFEPRGQTGHFEGSGHGSWGKRNKWGHKPFNKEL 180 Query: 181 FLQANCQFVVSEDQDYTAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRC 240 FLQANCQFVVSEDQDYTAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRC Sbjct: 181 FLQANCQFVVSEDQDYTAHFADPDTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRC 240 Query: 241 GHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATESHQYVVGDTITMQLMKRE 300 GHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATESHQYVVGDTITMQLMKRE Sbjct: 241 GHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATESHQYVVGDTITMQLMKRE 300 Query: 301 KGVLVALPKSKWMNVDHPIHLGDEQHSQYSKLLLASKEQVLHRVVLEEKVALEQQLAEEK 360 KGVLVALPKSKWMNVDHPIHLGDEQHSQYSKLLLASKEQVLHRVVLEEKVALEQQLAEEK Sbjct: 301 KGVLVALPKSKWMNVDHPIHLGDEQHSQYSKLLLASKEQVLHRVVLEEKVALEQQLAEEK 360 Query: 361 HTPESCFIEAAIQELKTREEALSGLAGSRREVTGVVAALEQLVLMAPLAKESVFQPRKGV 420 HTPESCFIEAAIQELKTREEALSGLAGSRREVTGVVAALEQLVLMAPLAKESVFQPRKGV Sbjct: 361 HTPESCFIEAAIQELKTREEALSGLAGSRREVTGVVAALEQLVLMAPLAKESVFQPRKGV 420 Query: 421 LEYLSAFDEETTEVCSLDTPSRPLALPLVEEEEAVSEPEPEGLPEACDDLELADDNLKEG 480 LEYLSAFDEETTEVCSLDTPSRPLALPLVEEEEAVSEPEPEGLPEACDDLELADDNLKEG Sbjct: 421 LEYLSAFDEETTEVCSLDTPSRPLALPLVEEEEAVSEPEPEGLPEACDDLELADDNLKEG 480 Query: 481 TICTESSQQEPITKSGFTRLSSSPCYYFYQAEDGQHMFLHPVNVRCLVREYGSLERSPEK 540 TICTESSQQEPITKSGFTRLSSSPCYYFYQAEDGQHMFLHPVNVRCLVREYGSLERSPEK Sbjct: 481 TICTESSQQEPITKSGFTRLSSSPCYYFYQAEDGQHMFLHPVNVRCLVREYGSLERSPEK 540 Query: 541 ISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKR 600 ISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKR Sbjct: 541 ISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKR 600 Query: 601 KRQRQKKAREERRRERRIEIEENKKQGKYPEVHIPLENLQQFPAFNSYTCSSDSALGPTS 660 KRQRQKKAREERRRERRIEIEENKKQGKYPEVHIPLENLQQFPAFNSYTCSSDSALGPTS Sbjct: 601 KRQRQKKAREERRRERRIEIEENKKQGKYPEVHIPLENLQQFPAFNSYTCSSDSALGPTS 660 Query: 661 TEGHGALSISPLSRSPGSHADFLLTPLSPTASQGSPSFCVGSLEEDSPFPSFAQMLRVGK 720 TEGHGALSISPLSRSPGSHADFLLTPLSPTASQGSPSFCVGSLEEDSPFPSFAQMLRVGK Sbjct: 661 TEGHGALSISPLSRSPGSHADFLLTPLSPTASQGSPSFCVGSLEEDSPFPSFAQMLRVGK 720 Query: 721 AKADVWPKTAPKKDENSLVPPAPVDSDGESDNSDRVPVPSFQNSFSQAIEAAFMKLDTPA 780 AKADVWPKTAPKKDENSLVPPAPVDSDGESDNSDRVPVPSFQNSFSQAIEAAFMKLDTPA Sbjct: 721 AKADVWPKTAPKKDENSLVPPAPVDSDGESDNSDRVPVPSFQNSFSQAIEAAFMKLDTPA 780 Query: 781 TSDPLSEEKGGKKRKKQKQKLLFSTSVVHTK 811 TSDPLSEEKGGKKRKKQKQKLLFSTSVVHTK Sbjct: 781 TSDPLSEEKGGKKRKKQKQKLLFSTSVVHTK 811 >gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo sapiens] Length = 326 Score = 50.1 bits (118), Expect = 8e-06 Identities = 61/260 (23%), Positives = 103/260 (39%), Gaps = 43/260 (16%) Query: 221 EVPSCPICLYPPTAAKITRCGHIFCWACIL--HYLSLSEKTWSKCPICYSSVHKKDLKSV 278 E +CPICL T CGH FC AC+ H S+ +K S CP+C S ++++ Sbjct: 11 EEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPENIR-- 68 Query: 279 VATESHQYVVGDTITMQLMKREKGVLVALPKSKWMNVDHPIHLGD-------EQHSQYSK 331 +++V ++ +K + VDH G+ E Sbjct: 69 ----PNRHVANIVEKLREVKL---------SPEGQKVDHCARHGEKLLLFCQEDGKVICW 115 Query: 332 LLLASKEQVLHRVVLEEKVALEQQLAEEKHTPESCFIEAAIQELKTREEALSGLAGSRRE 391 L S+E H L E+VA E Q+ ++AA++ L+ +++ L RE Sbjct: 116 LCERSQEHRGHHTFLTEEVAQEYQVK----------LQAALEMLRQKQQEAEELEADIRE 165 Query: 392 VTGVVAALEQLVLMAPLAKESVFQPRKGVLEYLSAFDEETTEVCSLDTPSRPLALPLVEE 451 Q LA F+ + +L++ EE+ E+ +L+ + L Sbjct: 166 EKASWKTQIQYDKTNVLAD---FEQLRDILDW-----EESNELQNLEKEEEDILKSLTNS 217 Query: 452 EEAVSEPEPEGLPEACDDLE 471 E + + + + L E DLE Sbjct: 218 ETEMVQ-QTQSLRELISDLE 236 >gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo sapiens] Length = 347 Score = 50.1 bits (118), Expect = 8e-06 Identities = 61/260 (23%), Positives = 103/260 (39%), Gaps = 43/260 (16%) Query: 221 EVPSCPICLYPPTAAKITRCGHIFCWACIL--HYLSLSEKTWSKCPICYSSVHKKDLKSV 278 E +CPICL T CGH FC AC+ H S+ +K S CP+C S ++++ Sbjct: 11 EEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPENIR-- 68 Query: 279 VATESHQYVVGDTITMQLMKREKGVLVALPKSKWMNVDHPIHLGD-------EQHSQYSK 331 +++V ++ +K + VDH G+ E Sbjct: 69 ----PNRHVANIVEKLREVKL---------SPEGQKVDHCARHGEKLLLFCQEDGKVICW 115 Query: 332 LLLASKEQVLHRVVLEEKVALEQQLAEEKHTPESCFIEAAIQELKTREEALSGLAGSRRE 391 L S+E H L E+VA E Q+ ++AA++ L+ +++ L RE Sbjct: 116 LCERSQEHRGHHTFLTEEVAQEYQVK----------LQAALEMLRQKQQEAEELEADIRE 165 Query: 392 VTGVVAALEQLVLMAPLAKESVFQPRKGVLEYLSAFDEETTEVCSLDTPSRPLALPLVEE 451 Q LA F+ + +L++ EE+ E+ +L+ + L Sbjct: 166 EKASWKTQIQYDKTNVLAD---FEQLRDILDW-----EESNELQNLEKEEEDILKSLTNS 217 Query: 452 EEAVSEPEPEGLPEACDDLE 471 E + + + + L E DLE Sbjct: 218 ETEMVQ-QTQSLRELISDLE 236 >gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo sapiens] Length = 493 Score = 48.1 bits (113), Expect = 3e-05 Identities = 62/260 (23%), Positives = 106/260 (40%), Gaps = 43/260 (16%) Query: 221 EVPSCPICLYPPTAAKITRCGHIFCWACIL--HYLSLSEKTWSKCPICYSSVHKKDLKSV 278 E +CPICL T CGH FC AC+ H S+ +K S CP+C S ++++ Sbjct: 11 EEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPENIR-- 68 Query: 279 VATESHQYVVGDTITMQLMKREKGVLVALPKSKWMNVDHPIHLGD-------EQHSQYSK 331 +++V L+++ + V ++ K VDH G+ E Sbjct: 69 ----PNRHVA------NLVEKLREVKLSPEGQK---VDHCARHGEKLLLFCQEDGKVICW 115 Query: 332 LLLASKEQVLHRVVLEEKVALEQQLAEEKHTPESCFIEAAIQELKTREEALSGLAGSRRE 391 L S+E H E+VA E Q+ ++AA++ L+ +++ L RE Sbjct: 116 LCERSQEHRGHHTFPTEEVAQEYQVK----------LQAALEMLRQKQQEAEELEADIRE 165 Query: 392 VTGVVAALEQLVLMAPLAKESVFQPRKGVLEYLSAFDEETTEVCSLDTPSRPLALPLVEE 451 Q LA F+ + +L++ EE+ E+ +L+ + L Sbjct: 166 EKASWKTQIQYDKTNVLAD---FEQLRDILDW-----EESNELQNLEKEEEDILKSLTNS 217 Query: 452 EEAVSEPEPEGLPEACDDLE 471 E + + + + L E DLE Sbjct: 218 ETEMVQ-QTQSLRELISDLE 236 >gi|21071052 helicase-like transcription factor [Homo sapiens] Length = 1009 Score = 48.1 bits (113), Expect = 3e-05 Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 1/51 (1%) Query: 225 CPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDL 275 C ICL T IT C H+FC CI + +E+ +KCP+C + +H+ +L Sbjct: 760 CAICLDSLTVPVITHCAHVFCKPCICQVIQ-NEQPHAKCPLCRNDIHEDNL 809 >gi|21071054 helicase-like transcription factor [Homo sapiens] Length = 1009 Score = 48.1 bits (113), Expect = 3e-05 Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 1/51 (1%) Query: 225 CPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDL 275 C ICL T IT C H+FC CI + +E+ +KCP+C + +H+ +L Sbjct: 760 CAICLDSLTVPVITHCAHVFCKPCICQVIQ-NEQPHAKCPLCRNDIHEDNL 809 >gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens] Length = 1884 Score = 46.2 bits (108), Expect = 1e-04 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Query: 212 VEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVH 271 V+ V ++ CPICL T+C HIFC C+L L+ +K S+CP+C + + Sbjct: 11 VQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLN-QKKGPSQCPLCKNDIT 69 Query: 272 KKDLK 276 K+ L+ Sbjct: 70 KRSLQ 74 >gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens] Length = 699 Score = 46.2 bits (108), Expect = 1e-04 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Query: 212 VEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVH 271 V+ V ++ CPICL T+C HIFC C+L L+ +K S+CP+C + + Sbjct: 11 VQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLN-QKKGPSQCPLCKNDIT 69 Query: 272 KKDLK 276 K+ L+ Sbjct: 70 KRSLQ 74 >gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens] Length = 759 Score = 46.2 bits (108), Expect = 1e-04 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Query: 212 VEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVH 271 V+ V ++ CPICL T+C HIFC C+L L+ +K S+CP+C + + Sbjct: 11 VQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLN-QKKGPSQCPLCKNDIT 69 Query: 272 KKDLK 276 K+ L+ Sbjct: 70 KRSLQ 74 >gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens] Length = 1863 Score = 46.2 bits (108), Expect = 1e-04 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Query: 212 VEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVH 271 V+ V ++ CPICL T+C HIFC C+L L+ +K S+CP+C + + Sbjct: 11 VQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLN-QKKGPSQCPLCKNDIT 69 Query: 272 KKDLK 276 K+ L+ Sbjct: 70 KRSLQ 74 >gi|237858656 ring finger protein 170 isoform b [Homo sapiens] Length = 200 Score = 45.1 bits (105), Expect = 3e-04 Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 6/67 (8%) Query: 225 CPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTW---SKCPICYSSVHKKDLKSVVAT 281 CPICL+ + T CGH+FC ACI+ Y +W CPIC + S + Sbjct: 87 CPICLHQASFPVETNCGHLFCGACIIAYWRYG--SWLGAISCPIC-RQTGSSEKSSRASE 143 Query: 282 ESHQYVV 288 ++HQ V Sbjct: 144 QTHQEAV 150 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 45.1 bits (105), Expect = 3e-04 Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 3/114 (2%) Query: 4 SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRY 63 SS ++++++S +S S+SSS+SS SS P A GP KP S K G +R Sbjct: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRS 2675 Query: 64 NRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRD 117 R+ P + +++S S + + + P R SS S G R D Sbjct: 2676 RSPRK---PIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGD 2726 Score = 39.3 bits (90), Expect = 0.015 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 3/109 (2%) Query: 4 SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKS---DGKNSSGS 60 SS ++++++S +S +SSS S GSS QP + P+ PK +G+ + Sbjct: 2540 SSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPT 2599 Query: 61 KRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSS 109 ++R S + S ++ S SSS S + + SS SS Sbjct: 2600 PAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648 Score = 36.2 bits (82), Expect = 0.13 Identities = 23/97 (23%), Positives = 45/97 (46%), Gaps = 2/97 (2%) Query: 2 PLSSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSK 61 P + P + + S K G + +SS S + PP+S +A S P+ K+ + + Sbjct: 1629 PRALPRRSRSGSS-SKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPR 1687 Query: 62 RYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQ 98 R + + + + +S RS+S +T ++ PP+ Sbjct: 1688 RRSSRSSPELTRKARLSRRS-RSASSSPETRSRTPPR 1723 Score = 35.4 bits (80), Expect = 0.21 Identities = 33/106 (31%), Positives = 49/106 (46%), Gaps = 14/106 (13%) Query: 3 LSSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKR 62 LSSP + A + + S S SS K Q PPR + +G S+PK+ + Sbjct: 762 LSSPRSKAKSRLSLRRSLSGSSPCPK--QKSQTPPRRSRSG---SSQPKAKSRTPP---- 812 Query: 63 YNRKRELSYP----KNESFNNQSRRSSSQKSKTFNKMPPQRGGGSS 104 R R S P K+++ + QS SSS K + PP++G +S Sbjct: 813 -RRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITS 857 Score = 35.4 bits (80), Expect = 0.21 Identities = 29/107 (27%), Positives = 47/107 (43%), Gaps = 7/107 (6%) Query: 4 SSPNAAATASDMDKNSGSNSS------SASSGSSKGQQPPRSASAGPAGES-KPKSDGKN 56 SSP + + S S SS S SS + PR+ + G S PK G Sbjct: 1712 SSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQ 1771 Query: 57 SSGSKRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGS 103 S S+ K + ++ S ++QS Q+S++ +++ +R GGS Sbjct: 1772 RSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGS 1818 Score = 35.0 bits (79), Expect = 0.28 Identities = 37/142 (26%), Positives = 56/142 (39%), Gaps = 12/142 (8%) Query: 8 AAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYNRKR 67 +A A K S+SSS+SS SS S+S+ +G S S+G + KR Sbjct: 2519 SALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKR 2578 Query: 68 ELS---YPKN--------ESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRR 116 S PK E + +R SS S + + SS SSS + Sbjct: 2579 VPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2638 Query: 117 DEVAEAQRAEFSPAQFSGPKKI 138 + + + SPA+ GP+ + Sbjct: 2639 SSSSSSSSSSPSPAK-PGPQAL 2659 Score = 31.6 bits (70), Expect = 3.1 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 1/69 (1%) Query: 23 SSSASSGSSKGQQPPRSASAGPAGESK-PKSDGKNSSGSKRYNRKRELSYPKNESFNNQS 81 SSS+ S + K ++ + G ES P+ + K SS K++ + E K+ S +S Sbjct: 177 SSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKS 236 Query: 82 RRSSSQKSK 90 +R S K + Sbjct: 237 KRKSKDKKR 245 Score = 30.4 bits (67), Expect = 6.9 Identities = 34/144 (23%), Positives = 57/144 (39%), Gaps = 14/144 (9%) Query: 5 SPNAAATASDMDKNSGSNSSSASSGSSKGQQPP---RSASAGPA--GESKPKSDGKNSSG 59 SP + + S SA G S + P RS S PA G S+ ++ + S Sbjct: 536 SPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSR 595 Query: 60 SKRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKM-------PPQRGGGSSKLFSSSFN 112 S+ R+R S ++SR + ++S+T + + P R G S+ + + Sbjct: 596 SRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARR 655 Query: 113 GGRRDE--VAEAQRAEFSPAQFSG 134 G R + +PA+ SG Sbjct: 656 GRSRSRTPARRGRSRSRTPARRSG 679 >gi|237858658 ring finger protein 170 isoform c [Homo sapiens] Length = 174 Score = 44.7 bits (104), Expect = 4e-04 Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 5/49 (10%) Query: 225 CPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTW---SKCPICYSSV 270 CPICL+ + T CGH+FC ACI+ Y +W CPIC +V Sbjct: 3 CPICLHQASFPVETNCGHLFCGACIIAYWRYG--SWLGAISCPICRQTV 49 >gi|237858654 ring finger protein 170 isoform a [Homo sapiens] Length = 258 Score = 44.7 bits (104), Expect = 4e-04 Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 5/49 (10%) Query: 225 CPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTW---SKCPICYSSV 270 CPICL+ + T CGH+FC ACI+ Y +W CPIC +V Sbjct: 87 CPICLHQASFPVETNCGHLFCGACIIAYWRYG--SWLGAISCPICRQTV 133 >gi|237858650 ring finger protein 170 isoform a [Homo sapiens] Length = 258 Score = 44.7 bits (104), Expect = 4e-04 Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 5/49 (10%) Query: 225 CPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTW---SKCPICYSSV 270 CPICL+ + T CGH+FC ACI+ Y +W CPIC +V Sbjct: 87 CPICLHQASFPVETNCGHLFCGACIIAYWRYG--SWLGAISCPICRQTV 133 >gi|56605981 tripartite motif-containing 72 [Homo sapiens] Length = 477 Score = 44.7 bits (104), Expect = 4e-04 Identities = 59/267 (22%), Positives = 104/267 (38%), Gaps = 38/267 (14%) Query: 220 HEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWS-KCPICYSSVHKKDLKS- 277 H+ SCP+CL A CGH FC AC+ + CP C + + L + Sbjct: 9 HQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALSTN 68 Query: 278 ----------VVATESHQYVVGDTITMQLMKREKGVLVALPKSKWMNVDHPIHLGDEQHS 327 + H D +++ ++++ ++ + S + H + E H+ Sbjct: 69 LQLARLVEGLAQVPQGHCEEHLDPLSI-YCEQDRALVCGVCASLGSHRGHRLLPAAEAHA 127 Query: 328 QYSKLLLASKEQVLHRVVLEEK--VALEQQLAEEKHTPES-------------CFIEAAI 372 + L K Q+ + +EK LE QL E + T F+ A Sbjct: 128 RLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMRVFLAALE 187 Query: 373 QELKTREEALSGLAG--SRREVTGVVAALEQLVLMAPLAKESVFQPRKGVLEYLSAFDEE 430 L E + G AG RRE+ + + LEQL M + +E +P+ E+L + Sbjct: 188 GSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQ---TEFLMKYCLV 244 Query: 431 TTEVCSLDTPSRP-----LALPLVEEE 452 T+ + + S P + LP++ ++ Sbjct: 245 TSRLQKILAESPPPARLDIQLPIISDD 271 >gi|5902054 ring finger protein 5 [Homo sapiens] Length = 180 Score = 43.1 bits (100), Expect = 0.001 Identities = 15/49 (30%), Positives = 28/49 (57%), Gaps = 1/49 (2%) Query: 225 CPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKK 273 C ICL A ++ CGH++CW C+ +L + +CP+C + + ++ Sbjct: 27 CNICLETAREAVVSVCGHLYCWPCLHQWLETRPER-QECPVCKAGISRE 74 >gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo sapiens] Length = 1082 Score = 42.7 bits (99), Expect = 0.001 Identities = 37/148 (25%), Positives = 65/148 (43%), Gaps = 24/148 (16%) Query: 13 SDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYNRKRELSYP 72 SD + SG S+ S S+ + +S+S +GES +SD ++ + R E Sbjct: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSE---- 734 Query: 73 KNESFNNQSRRSSSQKSKTFNKMPPQRGGGSS--KLFSSSFNGGRRDEVAEAQRAEFSPA 130 + QS +K+K K+P ++G SS + SS + + +E++ + PA Sbjct: 735 -----SEQSEEDGKRKTK--KKVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPA 787 Query: 131 QFS-----------GPKKINLNHLLNFT 147 +S K+I+L L +FT Sbjct: 788 SWSRKTPPSSKSAPATKEISLLDLEDFT 815 >gi|33356174 pinin, desmosome associated protein [Homo sapiens] Length = 717 Score = 42.7 bits (99), Expect = 0.001 Identities = 35/121 (28%), Positives = 61/121 (50%), Gaps = 10/121 (8%) Query: 4 SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRY 63 SS ++++++S +SGS+SSS SS S S+S+ +G S S SS S+ Sbjct: 577 SSSSSSSSSSSTSSSSGSSSSSGSSSSRSSS----SSSSSTSGSSSRDSSSSTSSSSESR 632 Query: 64 NRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEVAEAQ 123 +R R + + + + RRS +K + + + +R SSK SS G +D+ + + Sbjct: 633 SRSR----GRGHNRDRKHRRSVDRKRRDTSGL--ERSHKSSKGGSSRDTKGSKDKNSRSD 686 Query: 124 R 124 R Sbjct: 687 R 687 Score = 35.0 bits (79), Expect = 0.28 Identities = 29/123 (23%), Positives = 57/123 (46%), Gaps = 5/123 (4%) Query: 4 SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRY 63 SS + ++++S + S+SSS+S+ S + S+S + ES+ +S G+ + +++ Sbjct: 589 SSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRD--SSSSTSSSSESRSRSRGRGHNRDRKH 646 Query: 64 NRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGS--SKLFSSSFNGGRRDEVAE 121 R + ++ S +S +SS S K + S + S S G+R +E Sbjct: 647 RRSVDRK-RRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSE 705 Query: 122 AQR 124 R Sbjct: 706 RDR 708 Score = 32.3 bits (72), Expect = 1.8 Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 13/89 (14%) Query: 17 KNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYNRKRELSYPKNES 76 +N S S S SS SS S+S+G + S S +SS S + + Sbjct: 567 RNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS-------------SST 613 Query: 77 FNNQSRRSSSQKSKTFNKMPPQRGGGSSK 105 + SR SSS S + RG G ++ Sbjct: 614 SGSSSRDSSSSTSSSSESRSRSRGRGHNR 642 >gi|209529681 ring finger protein 185 isoform 1 [Homo sapiens] Length = 192 Score = 42.7 bits (99), Expect = 0.001 Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%) Query: 225 CPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHK 272 C ICL A I+ CGH+FCW C+ +L + CP+C + + + Sbjct: 39 CNICLDTAKDAVISLCGHLFCWPCLHQWLE-TRPNRQVCPVCKAGISR 85 >gi|31542783 ring finger protein 185 isoform 1 [Homo sapiens] Length = 192 Score = 42.7 bits (99), Expect = 0.001 Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%) Query: 225 CPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHK 272 C ICL A I+ CGH+FCW C+ +L + CP+C + + + Sbjct: 39 CNICLDTAKDAVISLCGHLFCWPCLHQWLE-TRPNRQVCPVCKAGISR 85 >gi|24797089 peroxisome biogenesis factor 10 isoform 1 [Homo sapiens] Length = 346 Score = 42.0 bits (97), Expect = 0.002 Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 4/44 (9%) Query: 223 PSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPIC 266 P C +CL T CGH+FCW CI + S + ++CP+C Sbjct: 291 PLCTLCLEERRHPTATPCGHLFCWECITAWCS----SKAECPLC 330 >gi|4505715 peroxisome biogenesis factor 10 isoform 2 [Homo sapiens] Length = 326 Score = 42.0 bits (97), Expect = 0.002 Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 4/44 (9%) Query: 223 PSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPIC 266 P C +CL T CGH+FCW CI + S + ++CP+C Sbjct: 271 PLCTLCLEERRHPTATPCGHLFCWECITAWCS----SKAECPLC 310 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 42.0 bits (97), Expect = 0.002 Identities = 38/140 (27%), Positives = 55/140 (39%), Gaps = 11/140 (7%) Query: 5 SPNAAATASDMDKNSGSNSS----------SASSGSSKGQQPPRSASAGPAGESKPKSDG 54 S N++ ++ D N SNSS S SS SS S+++ + ES SD Sbjct: 873 SSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN 932 Query: 55 KNSSGSKRYNRKRELSYPKNES-FNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNG 113 NSS S + + S N S +N S S+S S N SS SS + Sbjct: 933 SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992 Query: 114 GRRDEVAEAQRAEFSPAQFS 133 D + ++ S + S Sbjct: 993 DSSDSSDSSNSSDSSDSSDS 1012 Score = 41.2 bits (95), Expect = 0.004 Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 2/116 (1%) Query: 4 SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRY 63 S+ + ++ +SD +S S+SSS SS SS S+++ + +S SD +S S Sbjct: 660 SNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSS 719 Query: 64 NRKRELSYPKNESFNNQSRRS--SSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRD 117 N S N S ++ S S SS S + N SS SS + D Sbjct: 720 NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSD 775 Score = 40.8 bits (94), Expect = 0.005 Identities = 35/114 (30%), Positives = 49/114 (42%), Gaps = 8/114 (7%) Query: 4 SSPNAAATASDMDKNSGSNS-------SSASSGSSKGQQPPRSASAGPAGESKPKSDGKN 56 SS ++ + +SD +S SNS SS SS SS S+ + + +S SD N Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763 Query: 57 SSGSKRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSS 110 SS S + + S N S +N S +SS S + N SS SS Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDS-SNSSDSSDSSNSSDSSNSSDSSDSSDSS 816 Score = 40.0 bits (92), Expect = 0.009 Identities = 33/117 (28%), Positives = 50/117 (42%), Gaps = 2/117 (1%) Query: 4 SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSA--SAGPAGESKPKSDGKNSSGSK 61 SS ++ ++ SD +S S++SS SS SS S+ S G +S +SD NSS S Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS 868 Query: 62 RYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDE 118 + S + S +N+S SS + + +S S S N E Sbjct: 869 DSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSE 925 Score = 40.0 bits (92), Expect = 0.009 Identities = 31/121 (25%), Positives = 49/121 (40%), Gaps = 2/121 (1%) Query: 4 SSPNAAATASDMDKNSGSNS--SSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSK 61 S + ++ +SD D + SNS SS SS SS + S+ + +S SD +SS S Sbjct: 892 SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951 Query: 62 RYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEVAE 121 + S N S ++ S S S S + S S S N + ++ Sbjct: 952 NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011 Query: 122 A 122 + Sbjct: 1012 S 1012 Score = 37.4 bits (85), Expect = 0.056 Identities = 30/130 (23%), Positives = 51/130 (39%), Gaps = 4/130 (3%) Query: 4 SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRY 63 SS + ++ +SD D + SNSS +S S S+ + + +SK S S S Sbjct: 582 SSDSDSSDSSDSDSSDSSNSSDSSDSSDSSD----SSDSSDSSDSKSDSSKSESDSSDSD 637 Query: 64 NRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEVAEAQ 123 ++ ++S +N SS S + + SS SS + D + Sbjct: 638 SKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSN 697 Query: 124 RAEFSPAQFS 133 +E S + S Sbjct: 698 SSESSDSSDS 707 Score = 37.0 bits (84), Expect = 0.073 Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 5/107 (4%) Query: 4 SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRY 63 S+ + ++ +SD + SNSS +S+ S S+++ + +S SDG +S S R Sbjct: 804 SNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD----SSNSSDSSDSSDSSDGSDSDSSNRS 859 Query: 64 NRKREL-SYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSS 109 + S ++S N+ SS +++ N SS SS Sbjct: 860 DSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSS 906 Score = 37.0 bits (84), Expect = 0.073 Identities = 22/86 (25%), Positives = 40/86 (46%) Query: 4 SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRY 63 S + ++ +SD +S S+ SS SS SS S + + +S SD NSS S Sbjct: 1196 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDS 1255 Query: 64 NRKRELSYPKNESFNNQSRRSSSQKS 89 + + + N+ ++QS+ + + Sbjct: 1256 SDSSDSTSDSNDESDSQSKSGNGNNN 1281 Score = 36.2 bits (82), Expect = 0.13 Identities = 30/133 (22%), Positives = 51/133 (38%), Gaps = 4/133 (3%) Query: 5 SPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGES----KPKSDGKNSSGS 60 S + +SD D + SNSS +S S S+S + +S SD +SS S Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNS 601 Query: 61 KRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEVA 120 + + S + S ++ S+ SS+ + + S SS N D Sbjct: 602 SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN 661 Query: 121 EAQRAEFSPAQFS 133 + ++ S + S Sbjct: 662 SSNSSDSSDSSDS 674 Score = 36.2 bits (82), Expect = 0.13 Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 2/115 (1%) Query: 5 SPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYN 64 S +++ ++ D + S+SS +S S +S S +SK S NSS S + Sbjct: 595 SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNS 654 Query: 65 RKRELSYPKNESFNNQSRRS--SSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRD 117 + S N S ++ S S SS S + N SS SS + D Sbjct: 655 DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSD 709 Score = 35.0 bits (79), Expect = 0.28 Identities = 25/113 (22%), Positives = 46/113 (40%), Gaps = 4/113 (3%) Query: 5 SPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYN 64 S +++ +++ D N SNSS +S S+ S+++ + +S SD +S+ S N Sbjct: 773 SSDSSDSSNSSDSNDSSNSSDSSDSSNSSD----SSNSSDSSDSSDSSDSDSSNSSDSSN 828 Query: 65 RKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRD 117 + ++ S S S + N+ SS SS + D Sbjct: 829 SSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSD 881 Score = 31.6 bits (70), Expect = 3.1 Identities = 24/106 (22%), Positives = 41/106 (38%), Gaps = 3/106 (2%) Query: 5 SPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYN 64 S N +++ D NS + + + SKG + S S S +G N + N Sbjct: 481 SDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDD---N 537 Query: 65 RKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSS 110 K + K++S ++ S SS+ + + SS SS Sbjct: 538 DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSS 583 >gi|153791360 ret finger protein-like 4B [Homo sapiens] Length = 263 Score = 42.0 bits (97), Expect = 0.002 Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 6/72 (8%) Query: 224 SCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATES 283 SCP+CL + + C H+FC+ CI Y+ + + CP+C +D+ V A E Sbjct: 10 SCPVCLDFFSCSISLSCTHVFCFDCIQRYILENHDFRAMCPLC------RDVVKVPALEE 63 Query: 284 HQYVVGDTITMQ 295 Q V +T Q Sbjct: 64 WQVSVLTLMTKQ 75 >gi|121114298 cullin 4B isoform 1 [Homo sapiens] Length = 913 Score = 41.2 bits (95), Expect = 0.004 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 3/100 (3%) Query: 15 MDKNSGS---NSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYNRKRELSY 71 M ++SGS N A++ G P ++A A E + +DG S+ +KR+L+ Sbjct: 2 MSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61 Query: 72 PKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSF 111 + S N+ + R + + + PP + S+ +SSF Sbjct: 62 SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSF 101 Score = 30.0 bits (66), Expect = 9.0 Identities = 19/74 (25%), Positives = 36/74 (48%), Gaps = 1/74 (1%) Query: 5 SPNAAATASDM-DKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRY 63 SP+AAA A ++ G+ S++ + + K + S+S+ + + D +SS S Sbjct: 28 SPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPP 87 Query: 64 NRKRELSYPKNESF 77 + R+ + P SF Sbjct: 88 LQPRDSASPSTSSF 101 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 40.4 bits (93), Expect = 0.007 Identities = 52/226 (23%), Positives = 82/226 (36%), Gaps = 28/226 (12%) Query: 587 KETLEMFSDDIEKRKRQRQKKAREERRRERRIEIEENKKQ------------GKYPEVHI 634 KE E + E + +A+EE++ E + E K++ K P Sbjct: 561 KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS 620 Query: 635 PLENLQQFPAFNSYTCSSDSALGPTSTEGHGALSISPLSRSPGSHADFLLTPLSPTASQG 694 P+E + P S P +G SP+ +SP P SP +G Sbjct: 621 PVEEKGKSPVPKS----------PVEEKGK-----SPVPKSPVEEKGKSPVPKSPVEEKG 665 Query: 695 SPSFCVGSLEEDSPFPSFAQMLRVGKAKADVWPKTAPKKDENSLVPPAPVDSDGESDNSD 754 +EE + P + K+KA+V K K++E V AP + E Sbjct: 666 KSPVSKSPVEEKAKSPVPKSPVEEAKSKAEV-GKGEQKEEEEKEVKEAPKEEKVEKKEEK 724 Query: 755 RVPVPSFQNSFSQAIEAAFMKLDTPATSDPLSEEKGGKKRKKQKQK 800 VP + + S E A ++ T S + EK K+ K Q+ Sbjct: 725 PKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQ 770 >gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo sapiens] Length = 540 Score = 40.4 bits (93), Expect = 0.007 Identities = 52/226 (23%), Positives = 82/226 (36%), Gaps = 28/226 (12%) Query: 587 KETLEMFSDDIEKRKRQRQKKAREERRRERRIEIEENKKQ------------GKYPEVHI 634 KE E + E + +A+EE++ E + E K++ K P Sbjct: 185 KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS 244 Query: 635 PLENLQQFPAFNSYTCSSDSALGPTSTEGHGALSISPLSRSPGSHADFLLTPLSPTASQG 694 P+E + P S P +G SP+ +SP P SP +G Sbjct: 245 PVEEKGKSPVPKS----------PVEEKGK-----SPVPKSPVEEKGKSPVPKSPVEEKG 289 Query: 695 SPSFCVGSLEEDSPFPSFAQMLRVGKAKADVWPKTAPKKDENSLVPPAPVDSDGESDNSD 754 +EE + P + K+KA+V K K++E V AP + E Sbjct: 290 KSPVSKSPVEEKAKSPVPKSPVEEAKSKAEV-GKGEQKEEEEKEVKEAPKEEKVEKKEEK 348 Query: 755 RVPVPSFQNSFSQAIEAAFMKLDTPATSDPLSEEKGGKKRKKQKQK 800 VP + + S E A ++ T S + EK K+ K Q+ Sbjct: 349 PKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQ 394 >gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 [Homo sapiens] Length = 568 Score = 40.4 bits (93), Expect = 0.007 Identities = 25/88 (28%), Positives = 49/88 (55%), Gaps = 1/88 (1%) Query: 4 SSPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKP-KSDGKNSSGSKR 62 SS ++++++S +S S+SSS+SS SS S+S+ SKP K ++ + Sbjct: 150 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSK 209 Query: 63 YNRKRELSYPKNESFNNQSRRSSSQKSK 90 +R+ + ++ + +N+S + SS+K K Sbjct: 210 DSREHKSAFKEPSRDHNKSSKESSKKPK 237 Score = 37.0 bits (84), Expect = 0.073 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 9/92 (9%) Query: 6 PNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYNR 65 PN + S +S S+SSS+SS SS S+S+ + S S +SS S +++ Sbjct: 142 PNRSIHTSSSSSSSSSSSSSSSSSSSS------SSSSSSSSSSSSSSSSSSSSSSTSFSK 195 Query: 66 KRELSYPKNESFNNQSRRSSS---QKSKTFNK 94 +L E + SR S + S+ NK Sbjct: 196 PHKLMKEHKEKPSKDSREHKSAFKEPSRDHNK 227 >gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] Length = 2968 Score = 40.0 bits (92), Expect = 0.009 Identities = 35/137 (25%), Positives = 56/137 (40%), Gaps = 10/137 (7%) Query: 4 SSPNAAATASDMDKNSGSNSSSASSGSSKGQ----QPPRSASAGPAGESKPKSDGKNSSG 59 SS + ++++S +SGS + G G R+ SA + + P S +SS Sbjct: 2562 SSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSS 2621 Query: 60 SKRYNRKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEV 119 S + S + S ++ S SSS S + + SS SSS + DE Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-----SSSSSSSSSSSSSSSTTDED 2676 Query: 120 AEAQRA-EFSPAQFSGP 135 + E +PA +GP Sbjct: 2677 SSCSSDDEAAPAPTAGP 2693 Score = 38.9 bits (89), Expect = 0.019 Identities = 33/129 (25%), Positives = 52/129 (40%), Gaps = 1/129 (0%) Query: 5 SPNAAATASDMDKNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYN 64 SP+ A D + S S+SSS SSGSS S+ + GE + +G G+ N Sbjct: 2543 SPDKAQAEQDGAEESESSSSS-SSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRN 2601 Query: 65 RKRELSYPKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSFNGGRRDEVAEAQR 124 S + + ++ S SSS S + + SS SSS + + + Sbjct: 2602 CSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2661 Query: 125 AEFSPAQFS 133 + S + S Sbjct: 2662 SSSSSSSSS 2670 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.128 0.374 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 34,754,996 Number of Sequences: 37866 Number of extensions: 1749098 Number of successful extensions: 11427 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 180 Number of HSP's successfully gapped in prelim test: 286 Number of HSP's that attempted gapping in prelim test: 9314 Number of HSP's gapped (non-prelim): 2128 length of query: 811 length of database: 18,247,518 effective HSP length: 111 effective length of query: 700 effective length of database: 14,044,392 effective search space: 9831074400 effective search space used: 9831074400 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.