Guide to the Human Genome
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Search of human proteins with 122939208

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens]
         (885 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens]          1821   0.0  
gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]           1424   0.0  
gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens]      566   e-161
gi|134133279 SP140 nuclear body protein-like [Homo sapiens]           407   e-113
gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens]      358   1e-98
gi|190343010 SP110 nuclear body protein isoform a [Homo sapiens]      317   2e-86
gi|190343008 SP110 nuclear body protein isoform b [Homo sapiens]      206   6e-53
gi|52487277 SP140 nuclear body protein isoform 2 [Homo sapiens]       117   6e-26
gi|47419911 transcriptional intermediary factor 1 alpha isoform ...   100   1e-20
gi|47419909 transcriptional intermediary factor 1 alpha isoform ...   100   1e-20
gi|74027251 tripartite motif-containing 33 protein isoform beta ...    95   3e-19
gi|74027249 tripartite motif-containing 33 protein isoform alpha...    94   4e-19
gi|209977097 tripartite motif-containing 66 [Homo sapiens]             79   1e-14
gi|4557291 autoimmune regulator isoform 1 [Homo sapiens]               69   2e-11
gi|38016945 deformed epidermal autoregulatory factor 1 [Homo sap...    67   1e-10
gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]       62   2e-09
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa...    60   9e-09
gi|4557293 autoimmune regulator isoform 2 [Homo sapiens]               56   1e-07
gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo ...    56   2e-07
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ...    55   4e-07
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ...    55   4e-07
gi|158420731 chromodomain helicase DNA binding protein 3 isoform...    55   4e-07
gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo ...    54   6e-07
gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo ...    54   6e-07
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa...    53   1e-06
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    52   2e-06
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     50   1e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        49   2e-05
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]                47   8e-05
gi|217330641 IWS1 homolog [Homo sapiens]                               46   1e-04

>gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens]
          Length = 885

 Score = 1821 bits (4716), Expect = 0.0
 Identities = 885/885 (100%), Positives = 885/885 (100%)

Query: 1   MAGGGGDLSTRRLNECISPVANEMNHLPAHSHDLQRMFTEDQGVDDRLLYDIVFKHFKRN 60
           MAGGGGDLSTRRLNECISPVANEMNHLPAHSHDLQRMFTEDQGVDDRLLYDIVFKHFKRN
Sbjct: 1   MAGGGGDLSTRRLNECISPVANEMNHLPAHSHDLQRMFTEDQGVDDRLLYDIVFKHFKRN 60

Query: 61  KVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNLVPVQRVVYNVLSELEKTFNLP 120
           KVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNLVPVQRVVYNVLSELEKTFNLP
Sbjct: 61  KVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNLVPVQRVVYNVLSELEKTFNLP 120

Query: 121 VLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEEEREERSGLQLSLEQGTGENS 180
           VLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEEEREERSGLQLSLEQGTGENS
Sbjct: 121 VLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEEEREERSGLQLSLEQGTGENS 180

Query: 181 FRSLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAKRKDTTSDKDDSLGSQQTNEQCAQ 240
           FRSLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAKRKDTTSDKDDSLGSQQTNEQCAQ
Sbjct: 181 FRSLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAKRKDTTSDKDDSLGSQQTNEQCAQ 240

Query: 241 KAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEAELHNHGIQINSCSVRLVDIKKEK 300
           KAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEAELHNHGIQINSCSVRLVDIKKEK
Sbjct: 241 KAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEAELHNHGIQINSCSVRLVDIKKEK 300

Query: 301 PFSNSKVECQAQARTHHNQASDIIVISSEDSEGSTDVDEPLEVFISAPRSEPVINNDNPL 360
           PFSNSKVECQAQARTHHNQASDIIVISSEDSEGSTDVDEPLEVFISAPRSEPVINNDNPL
Sbjct: 301 PFSNSKVECQAQARTHHNQASDIIVISSEDSEGSTDVDEPLEVFISAPRSEPVINNDNPL 360

Query: 361 ESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASS 420
           ESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASS
Sbjct: 361 ESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASS 420

Query: 421 GALRSKHGEKAPMTSRSTSTWRIPSRKRRFSSSDFSDLSNGEELQETCSSSLRRGSGSQP 480
           GALRSKHGEKAPMTSRSTSTWRIPSRKRRFSSSDFSDLSNGEELQETCSSSLRRGSGSQP
Sbjct: 421 GALRSKHGEKAPMTSRSTSTWRIPSRKRRFSSSDFSDLSNGEELQETCSSSLRRGSGSQP 480

Query: 481 QEPENKKCSCVMCFPKGVPRSQEARTESSQASDMMDTMDVENNSTLEKHSGKRRKKRRHR 540
           QEPENKKCSCVMCFPKGVPRSQEARTESSQASDMMDTMDVENNSTLEKHSGKRRKKRRHR
Sbjct: 481 QEPENKKCSCVMCFPKGVPRSQEARTESSQASDMMDTMDVENNSTLEKHSGKRRKKRRHR 540

Query: 541 SKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRKRGPRIPKDENINF 600
           SKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRKRGPRIPKDENINF
Sbjct: 541 SKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRKRGPRIPKDENINF 600

Query: 601 KQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKWFTPREFEIEGDRGASKNWKLSIR 660
           KQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKWFTPREFEIEGDRGASKNWKLSIR
Sbjct: 601 KQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKWFTPREFEIEGDRGASKNWKLSIR 660

Query: 661 CGGYTLKVLMENKFLPEPPSTRKKRILESHNNTLVDPCPENSNICEVCNKWGRLFCCDTC 720
           CGGYTLKVLMENKFLPEPPSTRKKRILESHNNTLVDPCPENSNICEVCNKWGRLFCCDTC
Sbjct: 661 CGGYTLKVLMENKFLPEPPSTRKKRILESHNNTLVDPCPENSNICEVCNKWGRLFCCDTC 720

Query: 721 PRSFHEHCHIPSVEANKNPWSCIFCRIKTIQERCPESQSGHQESEVLMRQMLPEEQLKCE 780
           PRSFHEHCHIPSVEANKNPWSCIFCRIKTIQERCPESQSGHQESEVLMRQMLPEEQLKCE
Sbjct: 721 PRSFHEHCHIPSVEANKNPWSCIFCRIKTIQERCPESQSGHQESEVLMRQMLPEEQLKCE 780

Query: 781 FLLLKVYCDSKSCFFASEPYYNREGSQGPQKPMWLNKVKTSLNEQMYTRVEGFVQDMRLI 840
           FLLLKVYCDSKSCFFASEPYYNREGSQGPQKPMWLNKVKTSLNEQMYTRVEGFVQDMRLI
Sbjct: 781 FLLLKVYCDSKSCFFASEPYYNREGSQGPQKPMWLNKVKTSLNEQMYTRVEGFVQDMRLI 840

Query: 841 FHNHKEFYREDKFTRLGIQVQDIFEKNFRNIFAIQETSKNIIMFI 885
           FHNHKEFYREDKFTRLGIQVQDIFEKNFRNIFAIQETSKNIIMFI
Sbjct: 841 FHNHKEFYREDKFTRLGIQVQDIFEKNFRNIFAIQETSKNIIMFI 885


>gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]
          Length = 879

 Score = 1424 bits (3685), Expect = 0.0
 Identities = 699/701 (99%), Positives = 700/701 (99%)

Query: 1   MAGGGGDLSTRRLNECISPVANEMNHLPAHSHDLQRMFTEDQGVDDRLLYDIVFKHFKRN 60
           MAGGGGDLSTRRLNECISPVANEMNHLPAHSHDLQRMFTEDQGVDDRLLYDIVFKHFKRN
Sbjct: 1   MAGGGGDLSTRRLNECISPVANEMNHLPAHSHDLQRMFTEDQGVDDRLLYDIVFKHFKRN 60

Query: 61  KVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNLVPVQRVVYNVLSELEKTFNLP 120
           KVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNLVPVQRVVYNVLSELEKTFNLP
Sbjct: 61  KVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNLVPVQRVVYNVLSELEKTFNLP 120

Query: 121 VLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEEEREERSGLQLSLEQGTGENS 180
           VLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEEEREERSGLQLSLEQGTGENS
Sbjct: 121 VLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEEEREERSGLQLSLEQGTGENS 180

Query: 181 FRSLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAKRKDTTSDKDDSLGSQQTNEQCAQ 240
           FRSLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAKRKDTTSDKDDSLGSQQTNEQCAQ
Sbjct: 181 FRSLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAKRKDTTSDKDDSLGSQQTNEQCAQ 240

Query: 241 KAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEAELHNHGIQINSCSVRLVDIKKEK 300
           KAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEAELHNHGIQINSCSVRLVDIKKEK
Sbjct: 241 KAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEAELHNHGIQINSCSVRLVDIKKEK 300

Query: 301 PFSNSKVECQAQARTHHNQASDIIVISSEDSEGSTDVDEPLEVFISAPRSEPVINNDNPL 360
           PFSNSKVECQAQARTHHNQASDIIVISSEDSEGSTDVDEPLEVFISAPRSEPVINNDNPL
Sbjct: 301 PFSNSKVECQAQARTHHNQASDIIVISSEDSEGSTDVDEPLEVFISAPRSEPVINNDNPL 360

Query: 361 ESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASS 420
           ESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASS
Sbjct: 361 ESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASS 420

Query: 421 GALRSKHGEKAPMTSRSTSTWRIPSRKRRFSSSDFSDLSNGEELQETCSSSLRRGSGSQP 480
           GALRSKHGEKAPMTSRSTSTWRIPSRKRRFSSSDFSDLSNGEELQETCSSSLRRGSGSQP
Sbjct: 421 GALRSKHGEKAPMTSRSTSTWRIPSRKRRFSSSDFSDLSNGEELQETCSSSLRRGSGSQP 480

Query: 481 QEPENKKCSCVMCFPKGVPRSQEARTESSQASDMMDTMDVENNSTLEKHSGKRRKKRRHR 540
           QEPENKKCSCVMCFPKGVPRSQEARTESSQASDMMDTMDVENNSTLEKHSGKRRKKRRHR
Sbjct: 481 QEPENKKCSCVMCFPKGVPRSQEARTESSQASDMMDTMDVENNSTLEKHSGKRRKKRRHR 540

Query: 541 SKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRKRGPRIPKDENINF 600
           SKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRKRGPRIPKDENINF
Sbjct: 541 SKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRKRGPRIPKDENINF 600

Query: 601 KQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKWFTPREFEIEGDRGASKNWKLSIR 660
           KQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKWFTPREFEIEGDRGASKNWKLSIR
Sbjct: 601 KQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKWFTPREFEIEGDRGASKNWKLSIR 660

Query: 661 CGGYTLKVLMENKFLPEPPSTRKKRILESHNNTLVDPCPEN 701
           CGGYTLKVLMENKFLPEPPSTRKKRILESHNNTLVDPC E+
Sbjct: 661 CGGYTLKVLMENKFLPEPPSTRKKRILESHNNTLVDPCEEH 701


>gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens]
          Length = 867

 Score =  567 bits (1460), Expect = e-161
 Identities = 366/908 (40%), Positives = 485/908 (53%), Gaps = 137/908 (15%)

Query: 40  EDQGVDDRLLYDIVFKHFKRNKVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNL 99
           E Q + +++  + +F+ F+ NKVEI++AI + FPFL GLRDR  I+ +M+E  Q++ RNL
Sbjct: 29  EGQNLQEQVCPEPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNL 88

Query: 100 VPVQRVVYNVLSELEKTFNLPVLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEE 159
           VPV RV+Y VLSELEKTF    LEALFS +N+  YPDL  IY+ F+NV ++  PLQ +  
Sbjct: 89  VPVTRVMYCVLSELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQNVCYEHSPLQMNNV 148

Query: 160 EEREERSGLQLSLEQGTGENSFRSLTWPPSGSPSHAGTTPP--ENGLSEHPCETEQINAK 217
            + E+R  L   L  G  ENS           P  A ++ P  E G S   CE   +   
Sbjct: 149 NDLEDRPRL---LPYGKQENSNACHEMDDIAVPQEALSSSPRCEPGFSSESCEQLALPKA 205

Query: 218 RKDTTSDKDDSLGSQQTNEQCAQKAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEA 277
                 D    L                 SC+ +A+Q++ G++  EMP  LP D E    
Sbjct: 206 GGGDAEDAPSLLPGGGV------------SCK-LAIQIDEGES-EEMPKLLPYDTEV--- 248

Query: 278 ELHNHGIQINSCSVRLVDIKKEKPFSNSKVECQAQARTHHNQASDIIVISSEDSEGSTDV 337
            L ++G+           I   + +S +  E Q +    ++         ++D E   + 
Sbjct: 249 -LESNGM-----------IDAARTYSTAPGEKQGEEEGRNSPRK-----RNQDKEKYQES 291

Query: 338 DEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKK 397
            E         R +   +   P  +N E E ++  C  P    E  D             
Sbjct: 292 PEG--------RDKETFDLKTPQVTN-EGEPEKGLCLLPGEGEEGSD------------- 329

Query: 398 RVIGQDHDFSESSEEEAPAEASS-----GALRSKHGEKAPMTSRSTSTWRIPSRKRRF-- 450
                  D SE  + E P EASS     G++     E   + +   +    P ++     
Sbjct: 330 -------DCSEMCDGEEPQEASSSLARCGSVSCLSAETFDLKTPQVTNEGEPEKELSLLP 382

Query: 451 -----SSSDFSDLSNGEELQETCSSSLRRGS----------------------------- 476
                 S D S++ +GEE QE  SS  RRGS                             
Sbjct: 383 GEGEEGSDDCSEMCDGEERQEASSSLARRGSVSSELENHPMNEEGESEELASSLLYDNVP 442

Query: 477 GSQPQEPENKKCSCVMCFPKGVPRSQEARTESSQASDMMDTMDVENNSTLEKHSGKRRKK 536
           G++    EN+KCSCVMCF + VP S EARTES QA   MDT+D+ NNSTL K   KRRKK
Sbjct: 443 GAEQSAYENEKCSCVMCFSEEVPGSPEARTESDQACGTMDTVDIANNSTLGKPKRKRRKK 502

Query: 537 RRH---RSKVNGLQRGRKKDRPR---------KHLTLNNK-VQKKRWQQRGR------KA 577
           R H   R ++   +  ++ D  +         K   +N K + K R ++RG+      ++
Sbjct: 503 RGHGWSRMRMRRQENSQQNDNSKADGQVVSSEKKANVNLKDLSKIRGRKRGKPGTRFTQS 562

Query: 578 NTRPLKRRRKRGPRIPKDENINFKQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKW 637
           +    KR R R  R  KDE ++FK   LPVTCG VKG L+K++ +QG   KCIQ+ED KW
Sbjct: 563 DRAAQKRVRSRASRKHKDETVDFKAPLLPVTCGGVKGILHKKKLQQGILVKCIQTEDGKW 622

Query: 638 FTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENKFLPEPPSTR---KKRILESHNNTL 694
           FTP EFEI+G    SKNW+LS+RCGG+ L+ LMEN FLP+PP  R   KKRIL+S NN+ 
Sbjct: 623 FTPTEFEIKGGHARSKNWRLSVRCGGWPLRWLMENGFLPDPPRIRYRKKKRILKSQNNSS 682

Query: 695 VDPCPENSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSVEANKNPWSCIFCRIKTIQERC 754
           VDPC  N + CEVC   G LFCCDTC R FHE CHIP VEA + PW+CIFCR+K      
Sbjct: 683 VDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVEAERTPWNCIFCRMK----ES 738

Query: 755 PESQSGHQESEVLMRQMLPEEQLKCEFLLLKVYCDSKSCFFASEPYYN--REGSQGPQKP 812
           P SQ   QESEVL RQM PEEQLKCEFLLLKVYC S+S FFA  PYY   RE  QG ++P
Sbjct: 739 PGSQQCCQESEVLERQMCPEEQLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEP 798

Query: 813 MWLNKVKTSLNEQMYTRVEGFVQDMRLIFHNHKEFYREDKFTRLGIQVQDIFEKNFRNIF 872
           MWL+K+K  LNE  Y +VEGFVQDMRLIF NH+  Y+   F ++G +++  FEKNF+ +F
Sbjct: 799 MWLDKIKKRLNEHGYPQVEGFVQDMRLIFQNHRASYKYKDFGQMGFRLEAEFEKNFKEVF 858

Query: 873 AIQETSKN 880
           AIQET+ N
Sbjct: 859 AIQETNGN 866


>gi|134133279 SP140 nuclear body protein-like [Homo sapiens]
          Length = 580

 Score =  407 bits (1046), Expect = e-113
 Identities = 218/407 (53%), Positives = 267/407 (65%), Gaps = 28/407 (6%)

Query: 498 VPRSQEARTESSQASDMMDTMDVENNSTLEKHSGKRRKKRRH-------RSKVNGLQRGR 550
           VP S EAR ES QA   MDT+D+ NNSTL K   KRRKK+ H       R++ N  Q   
Sbjct: 177 VPESPEARKESDQACGKMDTVDIANNSTLGKPKRKRRKKKGHGWSRMGTRTQKNNQQNDN 236

Query: 551 KKD-----RPRKHLTLNNK-VQKKRWQQRGR------KANTRPLKRRRKRGPRIPKDENI 598
            K         K   +N K + K R ++RG+      +++  P KR R R  R  KDE +
Sbjct: 237 SKADGQLVSSEKKANMNLKDLSKIRGRKRGKPGTHFTQSDRAPQKRVRSRASRKHKDETV 296

Query: 599 NFKQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKWFTPREFEIEGDRGASKNWKLS 658
           +F+   LPVTCG VKG L+KE+ +QGT  KCIQ+ED KWFTP EFEI+G    SKNW+LS
Sbjct: 297 DFQAPLLPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGGYARSKNWRLS 356

Query: 659 IRCGGYTLKVLMENKFLPEPPS---TRKKRILESHNNTLVDPCPENSNICEVCNKWGRLF 715
           +RCGG+ L+ LME   LP PP      KKRIL+S NN+ VDPC  N + CEVC   G LF
Sbjct: 357 VRCGGWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPCMRNLDECEVCRDGGELF 416

Query: 716 CCDTCPRSFHEHCHIPSVEANKNPWSCIFCRIKTIQERCPESQSGHQESEVLMRQMLPEE 775
           CCDTC R FHE CHIP VE+ K PW+CIFCR+K      P SQ   QESEVL RQM PEE
Sbjct: 417 CCDTCSRVFHEDCHIPPVESEKTPWNCIFCRMK----ESPGSQQCCQESEVLERQMCPEE 472

Query: 776 QLKCEFLLLKVYCDSKSCFFASEPYYN--REGSQGPQKPMWLNKVKTSLNEQMYTRVEGF 833
           QLKCEFLLLKVYC S+S FFA  PYY   RE  QG ++PMWL+K+K  LNE  Y +VEGF
Sbjct: 473 QLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGF 532

Query: 834 VQDMRLIFHNHKEFYREDKFTRLGIQVQDIFEKNFRNIFAIQETSKN 880
           VQDMRLIF NH+  Y+   F ++G++++  FEK+F+ +FAIQET+ N
Sbjct: 533 VQDMRLIFQNHRASYKYKDFGQMGLRLEAEFEKDFKEVFAIQETNGN 579



 Score =  285 bits (729), Expect = 1e-76
 Identities = 141/175 (80%), Positives = 156/175 (89%)

Query: 1   MAGGGGDLSTRRLNECISPVANEMNHLPAHSHDLQRMFTEDQGVDDRLLYDIVFKHFKRN 60
           MAGGG DLSTR LN  +S VANEMNHLPAHS  LQR+FTEDQ VD+ L+YD VFKHFKR+
Sbjct: 1   MAGGGSDLSTRGLNGGVSQVANEMNHLPAHSQSLQRLFTEDQDVDEGLVYDTVFKHFKRH 60

Query: 61  KVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNLVPVQRVVYNVLSELEKTFNLP 120
           K+EISNAIKKTFPFLEGLRDR+LITNKMFEDS+DSCRNLVPVQRVVYNVLSELEKTFNL 
Sbjct: 61  KLEISNAIKKTFPFLEGLRDRELITNKMFEDSEDSCRNLVPVQRVVYNVLSELEKTFNLS 120

Query: 121 VLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEEEREERSGLQLSLEQG 175
           VLEALFS+VNMQEYPDLIHIYK F+N I DKL  QES+ +EREER  ++LSL+QG
Sbjct: 121 VLEALFSEVNMQEYPDLIHIYKSFKNAIQDKLSFQESDRKEREERPDIKLSLKQG 175


>gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens]
          Length = 713

 Score =  358 bits (919), Expect = 1e-98
 Identities = 259/841 (30%), Positives = 391/841 (46%), Gaps = 150/841 (17%)

Query: 47  RLLYDIVFKHFKRNKVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNLVPVQRVV 106
           R + + +F+HF   K+ I+ AI K FPF EGL D  +IT +M+ +S ++CRNL+PV RVV
Sbjct: 6   RAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIPVSRVV 65

Query: 107 YNVLSELEKTFNLPVLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEEEREERS 166
           +N+L++LE+TFNL +L  LFS +N++EYP+L+ IY+ F+ V             ER+ R 
Sbjct: 66  HNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRV---------GASYERQSRD 116

Query: 167 GLQLSLEQGTGENSFRSLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAKRKDTTSDKD 226
              + LE  TG     SL  P +  P      PP+   S  PC                +
Sbjct: 117 -TPILLEAPTGLAEGSSLHTPLALPPPQ----PPQPSCS--PCAPRV-----------SE 158

Query: 227 DSLGSQQTNEQCAQKAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEAELHNHGIQI 286
               SQQ++E  ++   P++    +   +  G                            
Sbjct: 159 PGTSSQQSDEILSESPSPSDPVLPLPALIQEG---------------------------- 190

Query: 287 NSCSVRLVDIKKEKPFSNSKVECQAQARTHHNQASDIIVISSEDSEGSTDVDEPLEVFIS 346
            S SV    +  +        E  +   +    ASD ++    D E      +P E+  S
Sbjct: 191 RSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKE------DPQEMPHS 244

Query: 347 APRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDF 406
              S P I +++P E ND +E QE + +     P     +K        +KR I     +
Sbjct: 245 PLGSMPEIRDNSP-EPNDPEEPQEVSST-----PSDKKGKK--------RKRCI-----W 285

Query: 407 SESSEEEAPAEASSGALRSKHG--------EKAPMTSRSTSTWRIPSRKRRFSSSDFSDL 458
           S             G   S+HG        ++ P     ++       + + + ++ +  
Sbjct: 286 STPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARK 345

Query: 459 SNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFP-KGVPRSQEARTESSQASDMMDT 517
           S  EE+ +  +S +  G  SQ      ++ +     P  G+    +   + +Q  D    
Sbjct: 346 SRSEEIIDG-TSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKD---- 400

Query: 518 MDVENNSTLEKHSGKRRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKA 577
            D   NS +     K R K   +S      R ++K + +   + + +  +K   +RG+  
Sbjct: 401 -DSTWNSEVMMRVQKARTKCARKS------RSKEKKKEKDICSSSKRRFQKNIHRRGK-- 451

Query: 578 NTRPLKRRRKRGPRIPKDENINFKQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKW 637
                          PK + ++F  S+LPVTCGE KG LYK++ K G+S KCI++ED  W
Sbjct: 452 ---------------PKSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTW 496

Query: 638 FTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENKFLPEPPSTRKKRILESHNNTLVDP 697
            TP EFE+EG    +KNWK +IRC G TL  L++ K                        
Sbjct: 497 LTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKRK------------------------ 532

Query: 698 CPENSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSVEANKNPWSCIFCRIKTIQERCPES 757
              NS+ CEVC + G+L CC TCPR FHE CHIP VEA +  WSC FCR+K    R   S
Sbjct: 533 ---NSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPVEAKRMLWSCTFCRMK----RSSGS 585

Query: 758 QSGHQESEVLMRQMLPEEQLKCEFLLLKVYCDSKSCFFASEPYYNREGSQGPQKPMWLNK 817
           Q  H  S+ L RQM P++QLKCEFLLLK YC  +S FF   P+  R+  +  Q+ MWL+ 
Sbjct: 586 QQCHHVSKTLERQMQPQDQLKCEFLLLKAYCHPQSSFFTGIPFNIRDYGEPFQEAMWLDL 645

Query: 818 VKTSLNEQMYTRVEGFVQDMRLIFHNHKEFYREDKFTRLGIQVQDIFEKNFRNIFAIQET 877
           VK  L  +MYT V  FV+DMRL+F NHK FY+   F ++G+ ++  FEK+ +++    E 
Sbjct: 646 VKERLITEMYT-VAWFVRDMRLMFRNHKTFYKASDFGQVGLDLEAEFEKDLKDVLGFHEA 704

Query: 878 S 878
           +
Sbjct: 705 N 705


>gi|190343010 SP110 nuclear body protein isoform a [Homo sapiens]
          Length = 689

 Score =  317 bits (813), Expect = 2e-86
 Identities = 246/841 (29%), Positives = 377/841 (44%), Gaps = 174/841 (20%)

Query: 47  RLLYDIVFKHFKRNKVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNLVPVQRVV 106
           R + + +F+HF   K+ I+ AI K FPF EGL D  +IT +M+ +S ++CRNL+PV RVV
Sbjct: 6   RAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIPVSRVV 65

Query: 107 YNVLSELEKTFNLPVLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEEEREERS 166
           +N+L++LE+TFNL +L  LFS +N++EYP+L+ IY+ F+ V             ER+ R 
Sbjct: 66  HNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRV---------GASYERQSRD 116

Query: 167 GLQLSLEQGTGENSFRSLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAKRKDTTSDKD 226
              + LE  TG     SL  P +  P      PP+   S  PC                +
Sbjct: 117 -TPILLEAPTGLAEGSSLHTPLALPPPQ----PPQPSCS--PCAPRV-----------SE 158

Query: 227 DSLGSQQTNEQCAQKAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEAELHNHGIQI 286
               SQQ++E  ++   P++    +   +  G                            
Sbjct: 159 PGTSSQQSDEILSESPSPSDPVLPLPALIQEG---------------------------- 190

Query: 287 NSCSVRLVDIKKEKPFSNSKVECQAQARTHHNQASDIIVISSEDSEGSTDVDEPLEVFIS 346
            S SV    +  +        E  +   +    ASD ++    D E      +P E+  S
Sbjct: 191 RSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKE------DPQEMPHS 244

Query: 347 APRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDF 406
              S P I +++P E ND +E QE + +     P     +K        +KR I     +
Sbjct: 245 PLGSMPEIRDNSP-EPNDPEEPQEVSST-----PSDKKGKK--------RKRCI-----W 285

Query: 407 SESSEEEAPAEASSGALRSKHG--------EKAPMTSRSTSTWRIPSRKRRFSSSDFSDL 458
           S             G   S+HG        ++ P     ++       + + + ++ +  
Sbjct: 286 STPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARK 345

Query: 459 SNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFP-KGVPRSQEARTESSQASDMMDT 517
           S  EE+ +  +S +  G  SQ      ++ +     P  G+    +   + +Q  D    
Sbjct: 346 SRSEEIIDG-TSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKD---- 400

Query: 518 MDVENNSTLEKHSGKRRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKA 577
            D   NS +     K R K   +S      R ++K + +   + + +  +K   +RG+  
Sbjct: 401 -DSTWNSEVMMRVQKARTKCARKS------RSKEKKKEKDICSSSKRRFQKNIHRRGK-- 451

Query: 578 NTRPLKRRRKRGPRIPKDENINFKQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKW 637
                          PK + ++F  S+LPVTCGE KG LYK++ K G+S KCI++ED  W
Sbjct: 452 ---------------PKSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTW 496

Query: 638 FTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENKFLPEPPSTRKKRILESHNNTLVDP 697
            TP EFE+EG    +KNWK +IRC G TL  L++ K                        
Sbjct: 497 LTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKRK------------------------ 532

Query: 698 CPENSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSVEANKNPWSCIFCRIKTIQERCPES 757
              NS+ CEVC + G+L CC TCPR FHE CHIP VEA +  WSC FCR+K    R   S
Sbjct: 533 ---NSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPVEAKRMLWSCTFCRMK----RSSGS 585

Query: 758 QSGHQESEVLMRQMLPEEQLKCEFLLLKVYCDSKSCFFASEPYYNREGSQGPQKPMWLNK 817
           Q  H  S+ L RQM P++QL  ++                EP+         Q+ MWL+ 
Sbjct: 586 QQCHHVSKTLERQMQPQDQLIRDY---------------GEPF---------QEAMWLDL 621

Query: 818 VKTSLNEQMYTRVEGFVQDMRLIFHNHKEFYREDKFTRLGIQVQDIFEKNFRNIFAIQET 877
           VK  L  +MYT V  FV+DMRL+F NHK FY+   F ++G+ ++  FEK+ +++    E 
Sbjct: 622 VKERLITEMYT-VAWFVRDMRLMFRNHKTFYKASDFGQVGLDLEAEFEKDLKDVLGFHEA 680

Query: 878 S 878
           +
Sbjct: 681 N 681


>gi|190343008 SP110 nuclear body protein isoform b [Homo sapiens]
          Length = 549

 Score =  206 bits (525), Expect = 6e-53
 Identities = 178/652 (27%), Positives = 283/652 (43%), Gaps = 118/652 (18%)

Query: 47  RLLYDIVFKHFKRNKVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNLVPVQRVV 106
           R + + +F+HF   K+ I+ AI K FPF EGL D  +IT +M+ +S ++CRNL+PV RVV
Sbjct: 6   RAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIPVSRVV 65

Query: 107 YNVLSELEKTFNLPVLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEEEREERS 166
           +N+L++LE+TFNL +L  LFS +N++EYP+L+ IY+ F+ V             ER+ R 
Sbjct: 66  HNILTQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRV---------GASYERQSRD 116

Query: 167 GLQLSLEQGTGENSFRSLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAKRKDTTSDKD 226
              + LE  TG     SL  P +  P      PP+   S  PC                +
Sbjct: 117 -TPILLEAPTGLAEGSSLHTPLALPPPQ----PPQPSCS--PCAPRV-----------SE 158

Query: 227 DSLGSQQTNEQCAQKAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEAELHNHGIQI 286
               SQQ++E  ++   P++    +   +  G                            
Sbjct: 159 PGTSSQQSDEILSESPSPSDPVLPLPALIQEG---------------------------- 190

Query: 287 NSCSVRLVDIKKEKPFSNSKVECQAQARTHHNQASDIIVISSEDSEGSTDVDEPLEVFIS 346
            S SV    +  +        E  +   +    ASD ++    D E      +P E+  S
Sbjct: 191 RSTSVTNDKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKE------DPQEMPHS 244

Query: 347 APRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDF 406
              S P I +++P E ND +E QE + +     P     +K        +KR I     +
Sbjct: 245 PLGSMPEIRDNSP-EPNDPEEPQEVSST-----PSDKKGKK--------RKRCI-----W 285

Query: 407 SESSEEEAPAEASSGALRSKHG--------EKAPMTSRSTSTWRIPSRKRRFSSSDFSDL 458
           S             G   S+HG        ++ P     ++       + + + ++ +  
Sbjct: 286 STPKRRHKKKSLPGGTASSRHGIQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARK 345

Query: 459 SNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFP-KGVPRSQEARTESSQASDMMDT 517
           S  EE+ +  +S +  G  SQ      ++ +     P  G+    +   + +Q  D    
Sbjct: 346 SRSEEIIDG-TSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKD---- 400

Query: 518 MDVENNSTLEKHSGKRRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKA 577
            D   NS +     K R K   +S      R ++K + +   + + +  +K   +RG+  
Sbjct: 401 -DSTWNSEVMMRVQKARTKCARKS------RSKEKKKEKDICSSSKRRFQKNIHRRGK-- 451

Query: 578 NTRPLKRRRKRGPRIPKDENINFKQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKW 637
                          PK + ++F  S+LPVTCGE KG LYK++ K G+S KCI++ED  W
Sbjct: 452 ---------------PKSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTW 496

Query: 638 FTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENKFLPEPPSTRKKRILES 689
            TP EFE+EG    +KNWK +IRC G TL  L+++  L  PP    KR L S
Sbjct: 497 LTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKSGLLLCPPRINLKRELNS 548


>gi|52487277 SP140 nuclear body protein isoform 2 [Homo sapiens]
          Length = 172

 Score =  117 bits (292), Expect = 6e-26
 Identities = 57/107 (53%), Positives = 78/107 (72%)

Query: 40  EDQGVDDRLLYDIVFKHFKRNKVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNL 99
           E Q + +++  + +F+ F+ NKVEI++AI + FPFL GLRDR  I+ +M+E  Q++ RNL
Sbjct: 29  EGQNLQEQVCPEPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNL 88

Query: 100 VPVQRVVYNVLSELEKTFNLPVLEALFSDVNMQEYPDLIHIYKGFEN 146
           VPV RV+Y VLSELEKTF    LEALFS +N+  YPDL  IY+ F+N
Sbjct: 89  VPVTRVMYCVLSELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQN 135


>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
            [Homo sapiens]
          Length = 1050

 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 62/182 (34%), Positives = 94/182 (51%), Gaps = 11/182 (6%)

Query: 701  NSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSV-EANKNPWSCIFCRIKTIQE-----RC 754
            N + C VC   G L CC+ CP+ FH  CH+P++       W C FCR  +  E       
Sbjct: 825  NEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDA 884

Query: 755  PESQSGHQESEVLMRQMLPEEQLKCEFLLLKVYCDSKSCFFASE-PYYNREGSQGPQKPM 813
            P   S  +++E L++ + P ++ KCE LLL +YC   S  F    P    +  +  + PM
Sbjct: 885  PSHNSEKKKTEGLVK-LTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPM 943

Query: 814  WLNKVKTSLNE--QMYTRVEGFVQDMRLIFHNHKEFYRED-KFTRLGIQVQDIFEKNFRN 870
             L+ +K  L E   MY++ E FV D RLIF N  EF   D +    GI++++ FE+  +N
Sbjct: 944  DLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKN 1003

Query: 871  IF 872
            ++
Sbjct: 1004 LY 1005


>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
           [Homo sapiens]
          Length = 1016

 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 62/182 (34%), Positives = 94/182 (51%), Gaps = 11/182 (6%)

Query: 701 NSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSV-EANKNPWSCIFCRIKTIQE-----RC 754
           N + C VC   G L CC+ CP+ FH  CH+P++       W C FCR  +  E       
Sbjct: 791 NEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDA 850

Query: 755 PESQSGHQESEVLMRQMLPEEQLKCEFLLLKVYCDSKSCFFASE-PYYNREGSQGPQKPM 813
           P   S  +++E L++ + P ++ KCE LLL +YC   S  F    P    +  +  + PM
Sbjct: 851 PSHNSEKKKTEGLVK-LTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPM 909

Query: 814 WLNKVKTSLNE--QMYTRVEGFVQDMRLIFHNHKEFYRED-KFTRLGIQVQDIFEKNFRN 870
            L+ +K  L E   MY++ E FV D RLIF N  EF   D +    GI++++ FE+  +N
Sbjct: 910 DLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKN 969

Query: 871 IF 872
           ++
Sbjct: 970 LY 971


>gi|74027251 tripartite motif-containing 33 protein isoform beta [Homo
            sapiens]
          Length = 1110

 Score = 95.1 bits (235), Expect = 3e-19
 Identities = 93/308 (30%), Positives = 128/308 (41%), Gaps = 39/308 (12%)

Query: 594  KDENINFKQSELPVTCGEV---KGTLYKERFKQGTSKKCIQSEDKKWFTPR-----EFEI 645
            K + +  KQ   P T  E+    G + +E+ + G    C+ S  +   TP        E 
Sbjct: 769  KSDQVKVKQE--PGTEDEICSFSGGVKQEKTEDGRRSACMLSSPESSLTPPLSTNLHLES 826

Query: 646  EGDRGASKNWKLSIR-------CGGYTLKVLMENKFLPEPPSTRKKRILESHNNTLVDPC 698
            E D  AS    + I        C    L  L+  K        R  RI    NN   DP 
Sbjct: 827  ELDALASLENHVKIEPADMNESCKQSGLSSLVNGKSPIRSLMHRSARIGGDGNNKDDDP- 885

Query: 699  PENSNICEVCNKWGRLFCCDTCPRSFHEHCHIPS-VEANKNPWSCIFCR---IKTIQERC 754
              N + C VC   G L CC+ CP+ FH  CH+P+ +      W C FCR      ++  C
Sbjct: 886  --NEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYDC 943

Query: 755  PESQSGHQESEVLMRQMLPEEQLKCEFLLLKVYCDSKSCFF-----ASEPYYNREGSQGP 809
               Q  H +     + + P +Q KCE LLL +YC   S  F     AS P Y +      
Sbjct: 944  DNLQ--HSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYKI----I 997

Query: 810  QKPMWLNKVKTSL---NEQMYTRVEGFVQDMRLIFHNHKEFYRED-KFTRLGIQVQDIFE 865
            +KPM L+ VK  L   + Q Y   + FV D+RLIF N + F   D +  + G  V   FE
Sbjct: 998  KKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEADSEVAQAGKAVALYFE 1057

Query: 866  KNFRNIFA 873
                 I++
Sbjct: 1058 DKLTEIYS 1065


>gi|74027249 tripartite motif-containing 33 protein isoform alpha
            [Homo sapiens]
          Length = 1127

 Score = 94.4 bits (233), Expect = 4e-19
 Identities = 90/297 (30%), Positives = 124/297 (41%), Gaps = 38/297 (12%)

Query: 594  KDENINFKQSELPVTCGEV---KGTLYKERFKQGTSKKCIQSEDKKWFTPR-----EFEI 645
            K + +  KQ   P T  E+    G + +E+ + G    C+ S  +   TP        E 
Sbjct: 769  KSDQVKVKQE--PGTEDEICSFSGGVKQEKTEDGRRSACMLSSPESSLTPPLSTNLHLES 826

Query: 646  EGDRGASKNWKLSIR-------CGGYTLKVLMENKFLPEPPSTRKKRILESHNNTLVDPC 698
            E D  AS    + I        C    L  L+  K        R  RI    NN   DP 
Sbjct: 827  ELDALASLENHVKIEPADMNESCKQSGLSSLVNGKSPIRSLMHRSARIGGDGNNKDDDP- 885

Query: 699  PENSNICEVCNKWGRLFCCDTCPRSFHEHCHIPS-VEANKNPWSCIFCR---IKTIQERC 754
              N + C VC   G L CC+ CP+ FH  CH+P+ +      W C FCR      ++  C
Sbjct: 886  --NEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYDC 943

Query: 755  PESQSGHQESEVLMRQMLPEEQLKCEFLLLKVYCDSKSCFF-----ASEPYYNREGSQGP 809
               Q  H +     + + P +Q KCE LLL +YC   S  F     AS P Y +      
Sbjct: 944  DNLQ--HSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYKI----I 997

Query: 810  QKPMWLNKVKTSL---NEQMYTRVEGFVQDMRLIFHNHKEFYREDKFTRLGIQVQDI 863
            +KPM L+ VK  L   + Q Y   + FV D+RLIF N + F    K  ++    Q+I
Sbjct: 998  KKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMMKVVQVYADTQEI 1054


>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
          Length = 1216

 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 66/216 (30%), Positives = 98/216 (45%), Gaps = 30/216 (13%)

Query: 671  ENKFLPEPPSTRKKRILESHNNTLVDPCP-ENSNICEVCNKWGRLFCCDTCPRSFHEHCH 729
            E++ +P  P  +K             P P EN + C VC   G L CCD CP+ FH  CH
Sbjct: 949  EHRLIPRTPGAKKG-----------PPAPIENEDFCAVCLNGGELLCCDRCPKVFHLSCH 997

Query: 730  IPS-VEANKNPWSCIFCRIKTIQER---CPE---SQSGHQESEVLMRQMLPEEQLKCEFL 782
            +P+ +      W C  CR  T  E    C     +Q G + S  L       +Q KCE L
Sbjct: 998  VPALLSFPGGEWVCTLCRSLTQPEMEYDCENACYNQPGMRASPGLSMY----DQKKCEKL 1053

Query: 783  LLKVYCDSKSCFFASEPY--YNREGSQGPQKPMWLNKVKTSLNEQ---MYTRVEGFVQDM 837
            +L + C++ S  F  EP     R   Q  ++PM L+ ++  L ++    YT  E  V D+
Sbjct: 1054 VLSLCCNNLSLPF-HEPVSPLARHYYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVVSDV 1112

Query: 838  RLIFHNHKEF-YREDKFTRLGIQVQDIFEKNFRNIF 872
            RL+F N  +F Y + +    G  ++  FE   + I+
Sbjct: 1113 RLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEIY 1148


>gi|4557291 autoimmune regulator isoform 1 [Homo sapiens]
          Length = 545

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 49/169 (28%), Positives = 74/169 (43%), Gaps = 15/169 (8%)

Query: 598 INFKQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKWFTPREFEIEGDRGASKNWKL 657
           +     ++P   G V+G L ++ F+ G SKKCIQ   + ++TP +FE   D G+ KN   
Sbjct: 192 VAMSSGDVPGARGAVEGILIQQVFESGGSKKCIQVGGE-FYTPSKFE---DSGSGKN--- 244

Query: 658 SIRCGGYTLKVLMENKFLPEPPSTRKKRILESHNNTLVDPCP-------ENSNICEVCNK 710
             R       ++         P   + R+ +  +       P       +N + C VC  
Sbjct: 245 KARSSSGPKPLVRAKGAQGAAPGGGEARLGQQGSVPAPLALPSDPQLHQKNEDECAVCRD 304

Query: 711 WGRLFCCDTCPRSFHEHCHIPSV-EANKNPWSCIFCRIKTIQERCPESQ 758
            G L CCD CPR+FH  C  P + E     W C  C   T+QE  P ++
Sbjct: 305 GGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQPRAE 353



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 8/90 (8%)

Query: 60  NKVEISNAIKKTFPFLEGLRDRDLITNKMFEDS-----QDSCRNLVPVQRVVYNVLSELE 114
           ++ EI+ A+   FP L  L D D++    F+++     ++ C         + + L   +
Sbjct: 14  HRTEIAVAVDSAFPLLHALADHDVVPEDKFQETLHLKEKEGCPQAF---HALLSWLLTQD 70

Query: 115 KTFNLPVLEALFSDVNMQEYPDLIHIYKGF 144
            T  L     LF D N++ Y  L  I   F
Sbjct: 71  STAILDFWRVLFKDYNLERYGRLQPILDSF 100



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 9/81 (11%)

Query: 673 KFLPEPPSTRKKRILES---HNNTLVDPCPENSNI----CEVCNKWGRLFCCDTCPRSFH 725
           K LP PPS      L+S   H    V P  + +      C VC     +  C  C  +FH
Sbjct: 395 KHLPAPPSAAPLPGLDSSALHPLLCVGPEGQQNLAPGARCGVCGDGTDVLRCTHCAAAFH 454

Query: 726 EHCHIPSVEANKNPWSCIFCR 746
             CH P+      P + + CR
Sbjct: 455 WRCHFPA--GTSRPGTGLRCR 473


>gi|38016945 deformed epidermal autoregulatory factor 1 [Homo
           sapiens]
          Length = 565

 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 32/73 (43%), Positives = 45/73 (61%), Gaps = 1/73 (1%)

Query: 603 SELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKWFTPREFEIEGDRGASKNWKLSIRCG 662
           SELPV C  + GTLYK R   G   +CI+ + + W++P EFE    R +SK+WK SIR  
Sbjct: 201 SELPVRCRNISGTLYKNRLGSGGRGRCIK-QGENWYSPTEFEAMAGRASSKDWKRSIRYA 259

Query: 663 GYTLKVLMENKFL 675
           G  L+ L+++  L
Sbjct: 260 GRPLQCLIQDGIL 272


>gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]
          Length = 835

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 42/178 (23%), Positives = 75/178 (42%), Gaps = 5/178 (2%)

Query: 700 ENSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSV-EANKNPWSCIFCRI-KTIQERCPES 757
           +++ IC VC K G L  C+ C   FH  CH+P++ +     WSC  C +   ++E     
Sbjct: 623 DSATICRVCQKPGDLVMCNQCEFCFHLDCHLPALQDVPGEEWSCSLCHVLPDLKEEDGSL 682

Query: 758 QSGHQESEVLMRQMLPEEQLKCEFLLLKVYCDSKSCFFASEPYYNREGSQGPQKPMWLNK 817
                +S  ++ ++ P  Q KCE +LL ++C             +      P   + L  
Sbjct: 683 SLDGADSTGVVAKLSPANQRKCERVLLALFCHEPCRPLHQLATDSTFSLDQPGGTLDLTL 742

Query: 818 VKTSLNEQM---YTRVEGFVQDMRLIFHNHKEFYREDKFTRLGIQVQDIFEKNFRNIF 872
           ++  L E++   Y+  + F QD+  +F    +   +    +  I +Q  FE      F
Sbjct: 743 IRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKLTEDKADVQSIIGLQRFFETRMNEAF 800


>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
           sapiens]
          Length = 1912

 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 53/196 (27%), Positives = 84/196 (42%), Gaps = 28/196 (14%)

Query: 575 RKANTR----PLKRRRKRG-PRIPKDENINFKQ-SELPVTCGEVKGTLYKERFKQGTSKK 628
           RKA T+    P  RR+ +G PR+P  +    K+ + L +  G             G+ +K
Sbjct: 258 RKAKTKEGKGPNARRKPKGSPRVPDAKKPKPKKVAPLKIKLGGF-----------GSKRK 306

Query: 629 CIQSEDKKWFTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENKFLPEPPSTRKKRILE 688
              SED       + ++E D   +     S+  G  +       K      +T+KK+  E
Sbjct: 307 RSSSEDD------DLDVESDFDDASINSYSVSDGSTSRSSRSRKKLR----TTKKKKKGE 356

Query: 689 SHNNTLVDPCPENSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSVE-ANKNPWSCIFCRI 747
                +     ++ + CEVC + G +  CDTCPR++H  C  P +E A +  WSC  C  
Sbjct: 357 EEVTAVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHMVCLDPDMEKAPEGKWSCPHCEK 416

Query: 748 KTIQERCPESQSGHQE 763
           + IQ    E  S  +E
Sbjct: 417 EGIQWEAKEDNSEGEE 432



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 24/63 (38%), Positives = 29/63 (46%), Gaps = 1/63 (1%)

Query: 684 KRILESHNNTLVDPCPENSNICEVCNKWGRLFCCDTCPRSFHEHC-HIPSVEANKNPWSC 742
           + ILE     L +    +   C VC   G L CCDTCP S+H HC + P  E     W C
Sbjct: 431 EEILEEVGGDLEEEDDHHMEFCRVCKDGGELLCCDTCPSSYHIHCLNPPLPEIPNGEWLC 490

Query: 743 IFC 745
             C
Sbjct: 491 PRC 493



 Score = 35.4 bits (80), Expect = 0.24
 Identities = 38/186 (20%), Positives = 67/186 (36%), Gaps = 40/186 (21%)

Query: 187  PPSGSPSHAGTTPPENGLSEHPCET----EQINAKRKDTTS-DKDDSLGSQQTNEQCAQK 241
            P + +PS  G T P       P E     E+ + K +++   +K+    + +T  +C Q 
Sbjct: 1538 PKTPTPSTPGDTQPNTPAPVPPAEDGIKIEENSLKEEESIEGEKEVKSTAPETAIECTQA 1597

Query: 242  AEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEAELHNHGIQINSCSVRLVDIKKEKP 301
              P    E++ V+   G+            E+  +AE+                 + E+P
Sbjct: 1598 PAPASEDEKVVVEPPEGE------------EKVEKAEVKE---------------RTEEP 1630

Query: 302  FSNSKVECQAQARTHHNQASDIIVISSEDSEGSTDVDEPLEVFISAPRSEPVINNDNPLE 361
                        +     A D+  I  ED E   + +E  EV +         N + P +
Sbjct: 1631 METEPKGAADVEKVEEKSAIDLTPIVVEDKEEKKEEEEKKEVMLQ--------NGETPKD 1682

Query: 362  SNDEKE 367
             NDEK+
Sbjct: 1683 LNDEKQ 1688


>gi|4557293 autoimmune regulator isoform 2 [Homo sapiens]
          Length = 348

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 25/62 (40%), Positives = 32/62 (51%), Gaps = 1/62 (1%)

Query: 698 CPENSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSV-EANKNPWSCIFCRIKTIQERCPE 756
           C +N + C VC   G L CCD CPR+FH  C  P + E     W C  C   T+QE  P 
Sbjct: 95  CQKNEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQPR 154

Query: 757 SQ 758
           ++
Sbjct: 155 AE 156



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 9/81 (11%)

Query: 673 KFLPEPPSTRKKRILES---HNNTLVDPCPENSNI----CEVCNKWGRLFCCDTCPRSFH 725
           K LP PPS      L+S   H    V P  + +      C VC     +  C  C  +FH
Sbjct: 198 KHLPAPPSAAPLPGLDSSALHPLLCVGPEGQQNLAPGARCGVCGDGTDVLRCTHCAAAFH 257

Query: 726 EHCHIPSVEANKNPWSCIFCR 746
             CH P+      P + + CR
Sbjct: 258 WRCHFPA--GTSRPGTGLRCR 276


>gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo
           sapiens]
          Length = 1135

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 48/169 (28%), Positives = 74/169 (43%), Gaps = 14/169 (8%)

Query: 678 PPSTRKKRILESHNNTLVDPCPENSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSVEANK 737
           P   +KK  L + NN   D    N   C VC++ G++ CC+ CPR +H  C +      +
Sbjct: 61  PIKKKKKPGLLNSNNKEQDG--RNDFYCWVCHREGQVLCCELCPRVYHAKC-LRLTSEPE 117

Query: 738 NPWSCIFCRIKTIQERCPESQSGHQESEVLMRQMLPEEQLK--CEFLLLKVYCDSKSCFF 795
             W C  C   T+ E C E+QS           ML  EQL    +F + K+       F 
Sbjct: 118 GDWFCPECEKITVAE-CIETQS-------KAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQ 169

Query: 796 ASEPY-YNREGSQGPQKPMWLNKVKTSLNEQMYTRVEGFVQDMRLIFHN 843
              P   + + ++    PM L  ++ +  ++MY   E F+ D + I HN
Sbjct: 170 KPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHN 218


>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
           [Homo sapiens]
          Length = 2000

 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 50/198 (25%), Positives = 84/198 (42%), Gaps = 21/198 (10%)

Query: 575 RKANTR----PLKRRRKRGPRIPKDENINFKQSELPVTCGEVKGTLYKERFKQGTSKKCI 630
           R+A T+    P  +RR + PR+P        +   P+   ++K  L   + K+G S    
Sbjct: 256 RRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPL---KIKLGLLGGKRKKGGSYVFQ 312

Query: 631 QSEDKKWFTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENKFLPEPPSTRKKRILESH 690
             E  +   P   E + D G+  +        G     +   K     P  +KK++L   
Sbjct: 313 SDEGPE---PEAEESDLDSGSVHS------ASGRPDGPVRTKKLKRGRPGRKKKKVLGCP 363

Query: 691 ---NNTLVDPCP-ENSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSVE-ANKNPWSCIFC 745
                  VD    ++ + CEVC + G +  CDTCPR++H  C  P ++ A +  WSC  C
Sbjct: 364 AVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHC 423

Query: 746 RIKTIQERCPESQSGHQE 763
             + +Q    E +  ++E
Sbjct: 424 EKEGVQWEAKEEEEEYEE 441



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 1/55 (1%)

Query: 700 ENSNICEVCNKWGRLFCCDTCPRSFHEHC-HIPSVEANKNPWSCIFCRIKTIQER 753
           ++   C VC   G L CCD C  S+H HC + P  +     W C  C    ++ R
Sbjct: 454 DHMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRCTCPVLKGR 508


>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
           [Homo sapiens]
          Length = 1966

 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 50/198 (25%), Positives = 84/198 (42%), Gaps = 21/198 (10%)

Query: 575 RKANTR----PLKRRRKRGPRIPKDENINFKQSELPVTCGEVKGTLYKERFKQGTSKKCI 630
           R+A T+    P  +RR + PR+P        +   P+   ++K  L   + K+G S    
Sbjct: 256 RRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPL---KIKLGLLGGKRKKGGSYVFQ 312

Query: 631 QSEDKKWFTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENKFLPEPPSTRKKRILESH 690
             E  +   P   E + D G+  +        G     +   K     P  +KK++L   
Sbjct: 313 SDEGPE---PEAEESDLDSGSVHS------ASGRPDGPVRTKKLKRGRPGRKKKKVLGCP 363

Query: 691 ---NNTLVDPCP-ENSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSVE-ANKNPWSCIFC 745
                  VD    ++ + CEVC + G +  CDTCPR++H  C  P ++ A +  WSC  C
Sbjct: 364 AVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHC 423

Query: 746 RIKTIQERCPESQSGHQE 763
             + +Q    E +  ++E
Sbjct: 424 EKEGVQWEAKEEEEEYEE 441



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 1/55 (1%)

Query: 700 ENSNICEVCNKWGRLFCCDTCPRSFHEHC-HIPSVEANKNPWSCIFCRIKTIQER 753
           ++   C VC   G L CCD C  S+H HC + P  +     W C  C    ++ R
Sbjct: 454 DHMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRCTCPVLKGR 508


>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
           [Homo sapiens]
          Length = 2059

 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 50/198 (25%), Positives = 84/198 (42%), Gaps = 21/198 (10%)

Query: 575 RKANTR----PLKRRRKRGPRIPKDENINFKQSELPVTCGEVKGTLYKERFKQGTSKKCI 630
           R+A T+    P  +RR + PR+P        +   P+   ++K  L   + K+G S    
Sbjct: 315 RRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPL---KIKLGLLGGKRKKGGSYVFQ 371

Query: 631 QSEDKKWFTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENKFLPEPPSTRKKRILESH 690
             E  +   P   E + D G+  +        G     +   K     P  +KK++L   
Sbjct: 372 SDEGPE---PEAEESDLDSGSVHS------ASGRPDGPVRTKKLKRGRPGRKKKKVLGCP 422

Query: 691 ---NNTLVDPCP-ENSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSVE-ANKNPWSCIFC 745
                  VD    ++ + CEVC + G +  CDTCPR++H  C  P ++ A +  WSC  C
Sbjct: 423 AVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHC 482

Query: 746 RIKTIQERCPESQSGHQE 763
             + +Q    E +  ++E
Sbjct: 483 EKEGVQWEAKEEEEEYEE 500



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 1/55 (1%)

Query: 700 ENSNICEVCNKWGRLFCCDTCPRSFHEHC-HIPSVEANKNPWSCIFCRIKTIQER 753
           ++   C VC   G L CCD C  S+H HC + P  +     W C  C    ++ R
Sbjct: 513 DHMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRCTCPVLKGR 567


>gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo
           sapiens]
          Length = 1188

 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 44/155 (28%), Positives = 69/155 (44%), Gaps = 15/155 (9%)

Query: 695 VDPCPE---NSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSVEANKNPWSCIFCRIKTIQ 751
           VD  P+   N   C VC++ G++ CC+ CPR +H  C +      +  W C  C   T+ 
Sbjct: 98  VDVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKC-LRLTSEPEGDWFCPECEKITVA 156

Query: 752 ERCPESQSGHQESEVLMRQMLPEEQLK--CEFLLLKVYCDSKSCFFASEPY-YNREGSQG 808
           E C E+QS           ML  EQL    +F + K+       F    P   + + ++ 
Sbjct: 157 E-CIETQS-------KAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEY 208

Query: 809 PQKPMWLNKVKTSLNEQMYTRVEGFVQDMRLIFHN 843
              PM L  ++ +  ++MY   E F+ D + I HN
Sbjct: 209 IFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHN 243


>gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo
           sapiens]
          Length = 1160

 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 44/155 (28%), Positives = 69/155 (44%), Gaps = 15/155 (9%)

Query: 695 VDPCPE---NSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSVEANKNPWSCIFCRIKTIQ 751
           VD  P+   N   C VC++ G++ CC+ CPR +H  C +      +  W C  C   T+ 
Sbjct: 98  VDVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKC-LRLTSEPEGDWFCPECEKITVA 156

Query: 752 ERCPESQSGHQESEVLMRQMLPEEQLK--CEFLLLKVYCDSKSCFFASEPY-YNREGSQG 808
           E C E+QS           ML  EQL    +F + K+       F    P   + + ++ 
Sbjct: 157 E-CIETQS-------KAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEY 208

Query: 809 PQKPMWLNKVKTSLNEQMYTRVEGFVQDMRLIFHN 843
              PM L  ++ +  ++MY   E F+ D + I HN
Sbjct: 209 IFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHN 243


>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
           sapiens]
          Length = 1954

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 10/90 (11%)

Query: 682 RKKRILESHNNTLVDPCPENSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSVE-ANKNPW 740
           RKK+ ++  +    D    + + CEVC + G +  CDTCPR++H  C  P +E A +  W
Sbjct: 327 RKKKRIDDGDGYETD----HQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPEGKW 382

Query: 741 SCIFCRIKTIQ-----ERCPESQSGHQESE 765
           SC  C  + IQ     +   E + G +E E
Sbjct: 383 SCPHCEKEGIQWEPKDDDDEEEEGGCEEEE 412



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 19/47 (40%), Positives = 23/47 (48%), Gaps = 1/47 (2%)

Query: 700 ENSNICEVCNKWGRLFCCDTCPRSFHEHC-HIPSVEANKNPWSCIFC 745
           ++   C VC   G L CCD CP S+H HC + P  E     W C  C
Sbjct: 414 DHMEFCRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGEWLCPRC 460


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 73/384 (19%), Positives = 134/384 (34%), Gaps = 19/384 (4%)

Query: 150  DKLPLQESEEEEREERSGLQLSLEQGTGENSFRSLTWPPSGSPSHAGTTPPENGLSEHPC 209
            D     +S + +    S    S +     NS  S       S S  G+    +  S+   
Sbjct: 808  DSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS----SDSSDSSDGSDSDSSNRSDSSN 863

Query: 210  ETEQINAKRKDTTSDKDDSLGSQQTNEQCAQKAEPTESCEQIAVQVNNGDAGREMPCPLP 269
             ++  ++     +SD  DS  S +++   +  ++ + S +  +   +N     +      
Sbjct: 864  SSDSSDSSDSSNSSDSSDSSDSNESSNS-SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSD 922

Query: 270  CDEESPEAELHNHGIQINSC-SVRLVDIKKEKPFSNSKVECQAQARTHHNQASDIIVISS 328
              E S  ++  N     NS  S    D       SNS     +   +  N +      +S
Sbjct: 923  SSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNS 982

Query: 329  EDSEGSTDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKL 388
             DS  S+D  +  +   S+  S+   ++D+   SN       +  S      +  D    
Sbjct: 983  SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042

Query: 389  STFRESFKKRVIGQDHDFSESSEEEAPAEASSGALRSKHGEKAPMTSRSTSTWRIPSRKR 448
            S   +S          D S+SS+    +++S  +  S   E +  +  S S+    S   
Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS 1102

Query: 449  RFS--------SSDFSDLSNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFPKGVPR 500
              S        SSD SD SN  +  ++  SS    S +     ++ + S           
Sbjct: 1103 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESS-----DSSDSS 1157

Query: 501  SQEARTESSQASDMMDTMDVENNS 524
                 ++SS +SD  D+ D  N+S
Sbjct: 1158 DSSDSSDSSDSSDSSDSSDSSNSS 1181



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 68/371 (18%), Positives = 130/371 (35%), Gaps = 6/371 (1%)

Query: 157 SEEEEREERSGLQLSLEQGTGENSFRSLTWPPSGSPSHAGTTPPENGLSEHPCETEQINA 216
           +E+++ +  S    S   G G N         SG      +    +  S     ++  ++
Sbjct: 510 AEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDS 569

Query: 217 KRKDTTSDKD-DSLGSQQTNEQCAQKAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESP 275
              D+ S  D DS  S  ++   +  ++ + S +      ++  +          D    
Sbjct: 570 DSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS 629

Query: 276 EAELHNHGIQINSCSVRLVDIKKEKPFSNSKVECQAQARTHHNQASDIIVISSEDSEGST 335
           E++  +   + +S      D       S+S     +   +  + +SD    SS DS  S+
Sbjct: 630 ESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSS--SSSDSSNSS 687

Query: 336 DVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESF 395
           D  +  +   S+  S+   ++D+    + +     ++ S      +  D    S   +S 
Sbjct: 688 DSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS 747

Query: 396 KKRVIGQDHDFSESSEEEAPAEASSGALRSKHGEKAPMTSRSTSTWRIPSRKRRFSS--S 453
                    D S+SS     +++S  +  S     +     S S+    S     SS  S
Sbjct: 748 DSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSS 807

Query: 454 DFSDLSNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFPKGVPRSQEARTESSQASD 513
           D SD S+  +   + SS     S S      +   S       G       R++SS +SD
Sbjct: 808 DSSDSSDSSDSDSSNSSDSSNSSDSSDSS-NSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866

Query: 514 MMDTMDVENNS 524
             D+ D  N+S
Sbjct: 867 SSDSSDSSNSS 877



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 69/376 (18%), Positives = 131/376 (34%), Gaps = 13/376 (3%)

Query: 156  ESEEEEREERSGLQLSLEQGTGENSFRSLTWPPSGSPSHAGTTPPENGLSEHPCETEQIN 215
            +S +      S         +  +S  S     S   S++  +   +  S++   ++  N
Sbjct: 881  DSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSN 940

Query: 216  AKRKDTTSDKDDSLGSQQTNEQCAQKAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESP 275
            +     +SD  +S  S  +++          +    +   N+ D+          D    
Sbjct: 941  SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1000

Query: 276  EAELHNHGIQINSCSVRLVDIKKEKPFSNSKVECQAQARTHHNQASDIIVISSEDSEGST 335
                 +     +S S    D       SNS     +   +  + +SD     S DS  S+
Sbjct: 1001 SNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSS--DSSDSSNSS 1058

Query: 336  DVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESF 395
            D  +  +   S+  S+   ++D+  ES+D  +   ++ S      +  D    S   +S 
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSS-ESSDSSDSSNSSDSSDS--SDSSDSSDSSDSSDSS 1115

Query: 396  KKRVIGQDHDFSESSEEEAPAEASSGALRSKHGEKAPMTSRSTSTWRIPSRKRRFSSSDF 455
                     D S+SS+    +++S+ +  S   E +  +  S S+    S      SSD 
Sbjct: 1116 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS-DSSDS 1174

Query: 456  SDLSNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFPKGVPRSQEART-------ES 508
            SD SN  +  ++  SS    S       ++   S           S  + +       ES
Sbjct: 1175 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNES 1234

Query: 509  SQASDMMDTMDVENNS 524
            S +SD  D+ D  N+S
Sbjct: 1235 SDSSDSSDSSDSSNSS 1250



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 65/369 (17%), Positives = 126/369 (34%), Gaps = 15/369 (4%)

Query: 156 ESEEEEREERSGLQLSLEQGTGENSFRSLTWPPSGSPSHAGTTPPENGLSEHPCETEQIN 215
           ES+  + + +S    S    + +NS  S +   S S   + ++   +  S         +
Sbjct: 630 ESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDS 689

Query: 216 AKRKDTTSDKDDSLGSQQTNEQCAQKAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESP 275
           +   D+++  + S  S  ++   +  ++ + S    +   N+ D+          D    
Sbjct: 690 SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS 749

Query: 276 EAELHNHGIQINSCSVRLVDIKKEKPFSNSKVECQAQARTHHNQASDIIVISSEDSEGST 335
                +     +S S    D       S+S     +   ++ + +SD    SS  S+ S 
Sbjct: 750 SNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSD----SSNSSDSSN 805

Query: 336 DVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESF 395
             D       S   S    ++ N  +S+D     +++ S         D    S    S 
Sbjct: 806 SSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSS 865

Query: 396 KKRVIGQDHDFSESSEEEAPAEASSGALRSKHGEKAPMTSRSTSTWRIPSRKRRFSSSDF 455
                    + S+SS+     E+S+ +  S     +   S  +S           +SSD 
Sbjct: 866 DSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSS-----------NSSDS 914

Query: 456 SDLSNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFPKGVPRSQEARTESSQASDMM 515
           SD SN  +  E+ +SS    S       ++   S           S  + +  S  S+  
Sbjct: 915 SDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS 974

Query: 516 DTMDVENNS 524
           D+ D  N+S
Sbjct: 975 DSSDSSNSS 983


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 55/259 (21%), Positives = 105/259 (40%), Gaps = 25/259 (9%)

Query: 364 DEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASSGAL 423
           ++ +G E    + ++V +    R+  ++  S   R   +    S  S +      SS + 
Sbjct: 158 EKLDGTEVNGRKIRLVEDKPGSRRRRSYSRS---RSHSRSRSRSRHSRKSRSRSGSSKSS 214

Query: 424 RSKHGEKAPMTSRSTSTWRIPSRKRRFSSSDFSDLSNGEELQETCSSSLRRGSGSQPQ-- 481
            SK   ++   SRS S  R  S+ R  S  + S   + E+ +    S+ +  S S+ Q  
Sbjct: 215 HSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAE 274

Query: 482 ----------EPENKKCSCVMCFPKGVPRSQEARTESSQASDMM----DTMDVENNSTLE 527
                     +P+++  S      K   RSQE R E  +   +         +  + +  
Sbjct: 275 EKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRS 334

Query: 528 KHSGKRRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRK 587
           +  G  R + R RSK    ++GRK+ R        ++ + +R ++RG K +++    ++K
Sbjct: 335 RSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKK 394

Query: 588 RGPRIPKDENINFKQSELP 606
                 K E+ +  QS  P
Sbjct: 395 ------KKEDTDRSQSRSP 407



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 59/328 (17%), Positives = 116/328 (35%), Gaps = 31/328 (9%)

Query: 283 GIQINSCSVRLVDIK----KEKPFSNSKVECQAQARTHHNQASDIIVISSEDSEGSTDVD 338
           G ++N   +RLV+ K    + + +S S+   ++++R+ H++ S     SS+ S       
Sbjct: 162 GTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSK---- 217

Query: 339 EPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKR 398
                  S  RS     + +   S      Q  + S+ +    P   +  S    + K R
Sbjct: 218 -------SRSRSR----SGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSR 266

Query: 399 VIGQDHDFSESSEEEAPAEASSGALRSKHGEKAPMTSRSTSTWRIPSRKRRFSSSDFSDL 458
                      S+++A  +  +     K   ++P   +S S  R  S++RR        +
Sbjct: 267 ---------SKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSV 317

Query: 459 SNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFPKGVPRSQEARTESSQASDMMDTM 518
           S G   +++   S  R          ++  S      KG  RS+E     S++    +  
Sbjct: 318 SRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERS 377

Query: 519 DVENNSTLEKHSGKRRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKAN 578
               +    K    ++KK+    +       R   + R+H    +  ++ R +      N
Sbjct: 378 RKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTN 437

Query: 579 TRPLKRRR---KRGPRIPKDENINFKQS 603
                R R   K  P +P +     K +
Sbjct: 438 QETRSRSRSNSKSKPNLPSESRSRSKSA 465


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 110/464 (23%), Positives = 165/464 (35%), Gaps = 74/464 (15%)

Query: 162  REERSGLQLSLEQGTGENSFRSLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAKRKDT 221
            R  RSG    L  G+G  S  SL+    G      T  P  G SE  C++         T
Sbjct: 1437 RRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRT--PSRGRSE--CDSSPEPKALPQT 1492

Query: 222  TSDKDDSLGSQQTNEQCAQKAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEAELHN 281
               +  S  S + N +C          E     V+     R    PL             
Sbjct: 1493 PRPRSRSPSSPELNNKCLTPQRERSGSES---SVDQKTVART---PL------------- 1533

Query: 282  HGIQINSCSVRLVDIK-----KEKPFSNSKVECQAQARTHHNQASDIIVISSEDSEGSTD 336
             G +  S S + +D+K     +E+  S+S  + +A+ RT   Q S         S    D
Sbjct: 1534 -GQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRS------RSGSSPEVD 1586

Query: 337  VDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFK 396
                L    S   S P +  D P  +   + G +++   P+  P P    + S    S K
Sbjct: 1587 SKSRLSPRRSRSGSSPEVK-DKPRAAPRAQSGSDSS-PEPK-APAPRALPRRSRSGSSSK 1643

Query: 397  KRVIGQDHDFSESSEEEAPAEASSGALRSKHGEKAPMTSRSTSTWRIPSR-------KRR 449
             R    +   S  S  E P ++ + A R       P T   T   R  SR       K R
Sbjct: 1644 GRGPSPEGSSSTESSPEHPPKSRT-ARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKAR 1702

Query: 450  FSSSDFSDLSNGE------------------ELQETCSSSLRRGSGSQPQ-EPENKKCSC 490
             S    S  S+ E                  E  E   SS RR S S P+ +  +++   
Sbjct: 1703 LSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRS 1762

Query: 491  VMCFPKGVPRSQ-EARTESSQASDMMDTMDVENNSTLEKHSGKRRKKRRHRSKVNGLQRG 549
                P+G+ RS+  +R E ++ +   D       S   + + +RR++ R RS+V   +RG
Sbjct: 1763 PSPKPRGLQRSRSRSRREKTRTTRRRD------RSGSSQSTSRRRQRSRSRSRVTRRRRG 1816

Query: 550  RKKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRKRGPRIP 593
                  R      +     R ++RGR + T P  R+R R    P
Sbjct: 1817 GSGYHSRSPARQESSRTSSR-RRRGR-SRTPPTSRKRSRSRTSP 1858



 Score = 38.1 bits (87), Expect = 0.036
 Identities = 58/255 (22%), Positives = 95/255 (37%), Gaps = 35/255 (13%)

Query: 380  PEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASSGALRSKHGEKAPMT----- 434
            PEP +       R S ++R        + S    +P+    G  RS+   +   T     
Sbjct: 1733 PEPAE-----KSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRR 1787

Query: 435  ------SRSTSTWRIPSR------KRRFSSSDFSDLSNGEELQETCSSSLRRGSGSQPQE 482
                  S+STS  R  SR      +RR   S +   S   +     SS  RRG    P  
Sbjct: 1788 RDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTP-- 1845

Query: 483  PENKKCSCVMCFPKGVPRSQEARTESSQASDMMDTMDVENNSTLEKHSGKRRKKRRHRSK 542
            P ++K S     P    RS+   + ++       T  +    +  + S   R++ R R+ 
Sbjct: 1846 PTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTS 1905

Query: 543  VNGLQRGRKKDRP---RKHLTLNNKVQKKRWQ------QRGRKANTRPLKRRRKRGPRIP 593
            V   +R R +  P   R+  +    V ++R +      +R  ++ T P+ RRR R  R P
Sbjct: 1906 VT-RRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRS-RTP 1963

Query: 594  KDENINFKQSELPVT 608
                   +    P+T
Sbjct: 1964 PVTRRRSRSRTSPIT 1978



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 39/185 (21%), Positives = 68/185 (36%), Gaps = 7/185 (3%)

Query: 409  SSEEEAPAEASSGALRSKHGEKAPMTSRSTSTWRIPSRKRRFSSSDFSDLSNGEELQETC 468
            +S + + +  S    +      +P T R + + R P   RR S S  S +S       T 
Sbjct: 1847 TSRKRSRSRTSPAPWKRSRSRASPATHRRSRS-RTPLISRRRSRSRTSPVSRRRSRSRTS 1905

Query: 469  SSSLRRGSGSQPQEPENKKCSCVMCFPKGVPRSQEARTESSQASDMMDTMDVENNSTLEK 528
             +  R  S + P      +       P    R   +RT +++      T  V    +  +
Sbjct: 1906 VTRRRSRSRASPVSRRRSRSRT----PPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSR 1961

Query: 529  HSGKRRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRKR 588
                 R  RR RS+ + + R R + R        ++ +     +R  ++ T P+ RRR R
Sbjct: 1962 TPPVTR--RRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSR 2019

Query: 589  GPRIP 593
                P
Sbjct: 2020 SRTPP 2024



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 36/139 (25%), Positives = 47/139 (33%), Gaps = 33/139 (23%)

Query: 153 PLQESEEEEREERSGL-QLSLEQGTGENSFRSLTWPPSGSPSHAGTTPPENGLSEHPCET 211
           P Q+S+   R  RSG  Q   +  T     RS + PP    S   +    +  S HP   
Sbjct: 786 PKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHP--- 842

Query: 212 EQINAKRKDTTSDKDDSLGSQQTNEQCAQKAEPTESCEQIAVQVNNGDAGREMPCPLPCD 271
                K K  T  +  S+ S Q NEQ                           P    C 
Sbjct: 843 -----KVKSGTPPRQGSITSPQANEQSVT------------------------PQRRSCF 873

Query: 272 EESPEAELHNHGIQINSCS 290
           E SP+ EL +     +SCS
Sbjct: 874 ESSPDPELKSRTPSRHSCS 892



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 54/262 (20%), Positives = 91/262 (34%), Gaps = 26/262 (9%)

Query: 334  STDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFR--KLSTF 391
            ST   +P  +    P  E   ++ +   S+       ++ S         D     L   
Sbjct: 2512 STGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQ 2571

Query: 392  RESFKKRVIGQDHDFSESSEEEAPAEASSGALRSKHGEKAPMTSRSTSTWRIPSRKRRFS 451
             E   KRV        E+  E  P E +    + +    +  +S S+S+    S     S
Sbjct: 2572 PEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSS 2631

Query: 452  SSDFSDLSNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFPKGVPRSQEAR--TESS 509
            SS  S  S+      +  S  + G  + P+    KK       P G  RS+  R   +S 
Sbjct: 2632 SSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKP------PPGERRSRSPRKPIDSL 2685

Query: 510  QASDMMDTMDVENNSTLEKHSGKRRKKRRHRSKVNGLQRGRKKD-RPRKHLTLNNKVQKK 568
            + S  +    VE      + S    + ++  S   G +RG++ D R   H          
Sbjct: 2686 RDSRSLSYSPVERRRPSPQPS---PRDQQSSSSERGSRRGQRGDSRSPSH---------- 2732

Query: 569  RWQQRGRKANTRPLKRRRKRGP 590
              ++R    + RP++ R  R P
Sbjct: 2733 --KRRRETPSPRPMRHRSSRSP 2752



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 30/111 (27%), Positives = 47/111 (42%), Gaps = 15/111 (13%)

Query: 470 SSLRRGSGSQPQEPENKKCSCVMCFPKGVPRSQEARTESSQASDMMDTMDVENNSTLEKH 529
           S +R  S S+   P+ KK        K   + +  R+ESS         + + +S  +KH
Sbjct: 172 SLVRESSSSRSPTPKQKK--------KKKKKDRGRRSESSSPR-----RERKKSSKKKKH 218

Query: 530 SGKRR-KKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKANT 579
             +   KKR+HRS     +R + KD+ RK         K R   R   A++
Sbjct: 219 RSESESKKRKHRSPTPKSKR-KSKDKKRKRSRSTTPAPKSRRAHRSTSADS 268



 Score = 30.0 bits (66), Expect = 9.9
 Identities = 20/92 (21%), Positives = 45/92 (48%), Gaps = 3/92 (3%)

Query: 500 RSQEART---ESSQASDMMDTMDVENNSTLEKHSGKRRKKRRHRSKVNGLQRGRKKDRPR 556
           R++EA+    E  +   ++       + T ++   K++K R  RS+ +  +R RKK   +
Sbjct: 156 RAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKK 215

Query: 557 KHLTLNNKVQKKRWQQRGRKANTRPLKRRRKR 588
           K     ++ +K++ +    K+  +   ++RKR
Sbjct: 216 KKHRSESESKKRKHRSPTPKSKRKSKDKKRKR 247


>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
          Length = 1437

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 20/48 (41%), Positives = 28/48 (58%), Gaps = 2/48 (4%)

Query: 699 PENSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSVEANKNPWSCIFCR 746
           P +S   + C K GRL CC++CP SFH  C   S+E  +  W+C  C+
Sbjct: 908 PSSSASKKKCEKGGRLLCCESCPASFHPEC--LSIEMPEGCWNCNDCK 953


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 84/371 (22%), Positives = 145/371 (39%), Gaps = 48/371 (12%)

Query: 156 ESEEEEREERSGLQLSLEQ----GTGENSFRSLTWPPSGSPS------HAGTTPPENGLS 205
           +SE EER E        E     G+   S  +   P S S +      HA  +  E+ + 
Sbjct: 94  DSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDSENED-VG 152

Query: 206 EHPCETEQINAKRKDTTSDKD--DSLGSQ----QTNEQCAQKAEPTESCEQIAVQVNNGD 259
           +HP    +I   +K   SD +  D+L  Q    ++ E    +A  +E+ E    ++++ +
Sbjct: 153 KHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSE 212

Query: 260 AGREMPCPLPCDEESPEAELHNHGIQINS--CSVRLVDIKKEKP----FSNSKVECQAQA 313
           +  E+P P   D ES E   H      N      R+ D + E P     S+S+ E   + 
Sbjct: 213 S-EELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKP 271

Query: 314 RTHHNQASDIIVISSEDSEGS---------TDVDEPLEVFISAPRSEPVINNDNPLESND 364
           R   +++ D     + DSE           ++ + P +   S   +E    +    ES+D
Sbjct: 272 RISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDD 331

Query: 365 ----EKEGQEATCSRPQIVPEP-MDFRKLSTF---RESFKKRVIGQDHDFSESSEEEAPA 416
               E +G++          +  MD +K  +     E  KK+ +  D D  E  EE+   
Sbjct: 332 DSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAK 391

Query: 417 EASSGALRSKHGEKAPMTSRSTSTWRIPSRKRRFSSSDFSDLSNGEELQETCSSSLRRGS 476
             ++    S+  EKA     S    R+ S      S   SD S   E  +T +S     +
Sbjct: 392 RKAAVLSDSEDEEKA-----SAKKSRVVSDADDSDSDAVSDKSGKRE--KTIASDSEEEA 444

Query: 477 GSQPQEPENKK 487
           G +  + +N++
Sbjct: 445 GKELSDKKNEE 455


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,467,038
Number of Sequences: 37866
Number of extensions: 1903113
Number of successful extensions: 7407
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 282
Number of HSP's that attempted gapping in prelim test: 6166
Number of HSP's gapped (non-prelim): 1158
length of query: 885
length of database: 18,247,518
effective HSP length: 111
effective length of query: 774
effective length of database: 14,044,392
effective search space: 10870359408
effective search space used: 10870359408
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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