Guide to the Human Genome
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Search of human proteins with 31542673

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31542673 chromatin modifying protein 6 [Homo sapiens]
         (201 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31542673 chromatin modifying protein 6 [Homo sapiens]              384   e-107
gi|40548422 chromatin modifying protein 4A [Homo sapiens]              84   6e-17
gi|22748643 chromatin modifying protein 4C [Homo sapiens]              76   2e-14
gi|28827795 chromatin modifying protein 4B [Homo sapiens]              67   1e-11
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap...    45   4e-05
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]                45   5e-05
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]                45   5e-05
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]            44   7e-05
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    44   7e-05
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    44   7e-05
gi|221316642 nuclear distribution gene E homolog 1 [Homo sapiens]      44   9e-05
gi|8923110 nuclear distribution gene E homolog 1 [Homo sapiens]        44   9e-05
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa...    44   1e-04
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa...    44   1e-04
gi|203096856 kinesin family member 7 [Homo sapiens]                    43   2e-04
gi|157785548 PAS domain containing 1 [Homo sapiens]                    43   2e-04
gi|148746195 trichohyalin [Homo sapiens]                               42   3e-04
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom...    42   3e-04
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom...    42   3e-04
gi|94721321 coiled-coil domain containing 11 [Homo sapiens]            42   3e-04
gi|7706353 vacuolar protein sorting 24 isoform 1 [Homo sapiens]        42   4e-04
gi|153945715 myosin VC [Homo sapiens]                                  42   5e-04
gi|41281453 serine/threonine kinase 2 [Homo sapiens]                   42   5e-04
gi|205277396 dynactin 1 isoform 4 [Homo sapiens]                       41   8e-04
gi|205277392 dynactin 1 isoform 3 [Homo sapiens]                       41   8e-04
gi|13259508 dynactin 1 isoform 2 [Homo sapiens]                        41   8e-04
gi|13259510 dynactin 1 isoform 1 [Homo sapiens]                        41   8e-04
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             41   8e-04
gi|221139761 zinc finger protein 853 [Homo sapiens]                    40   0.001
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     40   0.001

>gi|31542673 chromatin modifying protein 6 [Homo sapiens]
          Length = 201

 Score =  384 bits (986), Expect = e-107
 Identities = 201/201 (100%), Positives = 201/201 (100%)

Query: 1   MGNLFGRKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERA 60
           MGNLFGRKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERA
Sbjct: 1   MGNLFGRKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERA 60

Query: 61  KLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSI 120
           KLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSI
Sbjct: 61  KLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSI 120

Query: 121 EEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLPE 180
           EEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLPE
Sbjct: 121 EEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLPE 180

Query: 181 KIPENVPVKARPRQAELVAAS 201
           KIPENVPVKARPRQAELVAAS
Sbjct: 181 KIPENVPVKARPRQAELVAAS 201


>gi|40548422 chromatin modifying protein 4A [Homo sapiens]
          Length = 265

 Score = 84.3 bits (207), Expect = 6e-17
 Identities = 54/207 (26%), Positives = 109/207 (52%), Gaps = 12/207 (5%)

Query: 1   MGNLFGRKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERA 60
           +G LFG+ K+ +    ++AI +LK+    L + Q+ + Q++++E   A++     ++   
Sbjct: 47  LGRLFGKGKKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAAL 106

Query: 61  KLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSI 120
           + L +KKR+++QL  +T+  +S+LE   ++IE      +V+  ++   + + K +Q M I
Sbjct: 107 QALRRKKRFEQQLA-QTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDI 165

Query: 121 EEVERILDETQEAVEYQRQIDELLA---GSFTQEDEDAILEELSAITQEQI--------E 169
           ++V+ ++ +  E  E  +QI + ++   G     DED +LEEL  + QE++        +
Sbjct: 166 DKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGD 225

Query: 170 LPEVPSEPLPEKIPENVPVKARPRQAE 196
             E PS  LP     ++P    P+  E
Sbjct: 226 KEEEPSVKLPSVPSTHLPAGPAPKVDE 252


>gi|22748643 chromatin modifying protein 4C [Homo sapiens]
          Length = 233

 Score = 76.3 bits (186), Expect = 2e-14
 Identities = 48/206 (23%), Positives = 104/206 (50%), Gaps = 12/206 (5%)

Query: 6   GRKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLK 65
           G  K        +A+++L++  + L + Q+ +  +++RE ALA++     ++   + L +
Sbjct: 12  GSSKSRAAPSPQEALVRLRETEEMLGKKQEYLENRIQREIALAKKHGTQNKRAALQALKR 71

Query: 66  KKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEEVER 125
           KKR+++Q L + +  +S++E   +++E +    +V+  + F  + +  +H+ M + +++ 
Sbjct: 72  KKRFEKQ-LTQIDGTLSTIEFQREALENSHTNTEVLRNMGFAAKAMKSVHENMDLNKIDD 130

Query: 126 ILDETQEAVEYQRQIDELLA---GSFTQEDEDAILEELSAITQEQ-------IELPEVPS 175
           ++ E  E  +  ++I E  +   G     DED ++ EL  + QE+       I LP VPS
Sbjct: 131 LMQEITEQQDIAQEISEAFSQRVGFGDDFDEDELMAELEELEQEELNKKMTNIRLPNVPS 190

Query: 176 EPLPEKIPENVPVKARPRQAELVAAS 201
             LP + P   P  +   +    A+S
Sbjct: 191 SSLPAQ-PNRKPGMSSTARRSRAASS 215


>gi|28827795 chromatin modifying protein 4B [Homo sapiens]
          Length = 224

 Score = 66.6 bits (161), Expect = 1e-11
 Identities = 46/199 (23%), Positives = 97/199 (48%), Gaps = 20/199 (10%)

Query: 2   GNLFGR---KKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKE 58
           G LFG    K         +AI +L+   + L + Q+ + +++E+E   A++     ++ 
Sbjct: 5   GKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRA 64

Query: 59  RAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVM 118
             + L +KKRY++QL  + +  +S++E   +++E      +V++ + +  + +   H  M
Sbjct: 65  ALQALKRKKRYEKQLA-QIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNM 123

Query: 119 SIEEVERILDETQEAVEYQRQIDELLA---GSFTQEDEDAILEELSAITQEQIE------ 169
            I++V+ ++ +  +  E   +I   ++   G   + DED ++ EL  + QE+++      
Sbjct: 124 DIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEI 183

Query: 170 -------LPEVPSEPLPEK 181
                  LP VPS  LP K
Sbjct: 184 SGPETVPLPNVPSIALPSK 202


>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 479

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 38/146 (26%), Positives = 78/146 (53%), Gaps = 7/146 (4%)

Query: 1   MGNLFGRKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERA 60
           M +L  R+++ R+ EQ++   +L +Q ++L + ++R+ +Q ER      + LR+ ++ER 
Sbjct: 189 MLSLLNRRQEERLREQEE---RLHEQEERLHEQEERLCEQEER-LCEQEERLRE-QEERL 243

Query: 61  KLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSI 120
           +   ++   QE+ L   E ++   E  +   E    + +++E ++   E   +  +   +
Sbjct: 244 REQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERL 303

Query: 121 EEVERILDETQEAVEYQ--RQIDELL 144
            E ER+LDE +E +E +  RQ DE L
Sbjct: 304 LERERLLDEVEELLEQERLRQQDERL 329


>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
          Length = 1220

 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 49/184 (26%), Positives = 90/184 (48%), Gaps = 24/184 (13%)

Query: 7   RKKQSRVTEQDKAILQLKQQRDKLRQYQKR---IAQQLERERALARQLLRDGRK-----E 58
           RK+Q R+ + ++A  Q +++R++  Q +KR   + +QLE++R L RQ   + RK     E
Sbjct: 377 RKEQERLAQLERAE-QERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERRE 435

Query: 59  RAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLN-KMHQV 117
            AK  L+++R  E   +R +  ++      + I   + + K +E   F  E LN K HQ 
Sbjct: 436 AAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLE---FELEALNDKKHQ- 491

Query: 118 MSIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEP 177
                +E  L + +  +  QRQ  E      T +  +  + E++ + Q+  E  ++    
Sbjct: 492 -----LEGKLQDIRCRLTTQRQEIE-----STNKSRELRIAEITHLQQQLQESQQMLGRL 541

Query: 178 LPEK 181
           +PEK
Sbjct: 542 IPEK 545


>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
          Length = 1721

 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 49/184 (26%), Positives = 90/184 (48%), Gaps = 24/184 (13%)

Query: 7   RKKQSRVTEQDKAILQLKQQRDKLRQYQKR---IAQQLERERALARQLLRDGRK-----E 58
           RK+Q R+ + ++A  Q +++R++  Q +KR   + +QLE++R L RQ   + RK     E
Sbjct: 377 RKEQERLAQLERAE-QERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERRE 435

Query: 59  RAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLN-KMHQV 117
            AK  L+++R  E   +R +  ++      + I   + + K +E   F  E LN K HQ 
Sbjct: 436 AAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLE---FELEALNDKKHQ- 491

Query: 118 MSIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEP 177
                +E  L + +  +  QRQ  E      T +  +  + E++ + Q+  E  ++    
Sbjct: 492 -----LEGKLQDIRCRLTTQRQEIE-----STNKSRELRIAEITHLQQQLQESQQMLGRL 541

Query: 178 LPEK 181
           +PEK
Sbjct: 542 IPEK 545


>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 523

 Score = 44.3 bits (103), Expect = 7e-05
 Identities = 41/181 (22%), Positives = 86/181 (47%), Gaps = 14/181 (7%)

Query: 6   GRKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLK 65
           GR+ Q+ V       L  ++Q ++LR+ ++R+ +Q ER R    +L    ++ER +   +
Sbjct: 177 GRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCE--QEERLREQEE 234

Query: 66  KKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEEVER 125
           + R QE+ L   E ++   E  +   E    E +  E L+   E L++  + +  E+ ER
Sbjct: 235 RLREQEERLCEQEERLREHEERLCEQEERLCEQE--ERLREQEERLHEQEERL-CEQEER 291

Query: 126 ILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLPEKIPEN 185
           + ++ +   E + ++         +E E+ + E+   + +++  L E    P  E++ E 
Sbjct: 292 LREQEERLCEQEERL---------REQEERLCEQEERLREQEERLCEQEKLPGQERLLEE 342

Query: 186 V 186
           V
Sbjct: 343 V 343



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 38/158 (24%), Positives = 79/158 (50%), Gaps = 15/158 (9%)

Query: 7   RKKQSRVTEQDKAILQ----LKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKL 62
           R+ + R+ EQ++ + +    L++Q ++L + ++R+ +Q ER R    +L    ++ER   
Sbjct: 251 REHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCE--QEERL-- 306

Query: 63  LLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEE 122
                R QE+ L   E ++   E  +   E    + +++E ++   E   +  +   + E
Sbjct: 307 -----REQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLE 361

Query: 123 VERILDETQEAVEYQ--RQIDELLAGSFTQEDEDAILE 158
            ER+L+E +E +E +  RQ DE L    T ++ + + E
Sbjct: 362 RERLLEEVEELLEQERLRQQDERLWQQETLQELERLRE 399



 Score = 30.8 bits (68), Expect = 0.81
 Identities = 30/156 (19%), Positives = 70/156 (44%), Gaps = 6/156 (3%)

Query: 22  QLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKKKRYQEQLLDRTENQI 81
           QL+ + + LR+  + + +QL+ E    + L    R++  +L  +++R +EQ  +R   Q 
Sbjct: 161 QLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQ-EERLREQE 219

Query: 82  SSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEEVERILDETQEAVEYQRQID 141
             L    + +   +  ++  E      E   + H+    E+ ER+ ++ +   E + ++ 
Sbjct: 220 ERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLH 279

Query: 142 ELLAGSFTQED-----EDAILEELSAITQEQIELPE 172
           E       QE+     E+ + E+   + +++  L E
Sbjct: 280 EQEERLCEQEERLREQEERLCEQEERLREQEERLCE 315


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 44.3 bits (103), Expect = 7e-05
 Identities = 42/183 (22%), Positives = 93/183 (50%), Gaps = 9/183 (4%)

Query: 8   KKQSRVTEQDKAI----LQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLL 63
           +++ ++ EQ++ +    L++++Q +K+ + ++++ +Q E+ R    ++ R   K R +  
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQE- 359

Query: 64  LKKKRYQEQLLDRTENQISSLEAMVQSIE--FTQIEMKVMEGLQFGNECLNKMHQVMSIE 121
            +K R QE+ + R E +I   +  +Q  E    + E K+ E  +   E + +  + M  E
Sbjct: 360 -EKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMR-E 417

Query: 122 EVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLPEK 181
           + E+I ++ +E    + +I EL      QE++   +EE     +E+++  E   +   EK
Sbjct: 418 QDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEK 477

Query: 182 IPE 184
           I E
Sbjct: 478 IQE 480


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 44.3 bits (103), Expect = 7e-05
 Identities = 42/183 (22%), Positives = 93/183 (50%), Gaps = 9/183 (4%)

Query: 8   KKQSRVTEQDKAI----LQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLL 63
           +++ ++ EQ++ +    L++++Q +K+ + ++++ +Q E+ R    ++ R   K R +  
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQE- 359

Query: 64  LKKKRYQEQLLDRTENQISSLEAMVQSIE--FTQIEMKVMEGLQFGNECLNKMHQVMSIE 121
            +K R QE+ + R E +I   +  +Q  E    + E K+ E  +   E + +  + M  E
Sbjct: 360 -EKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMR-E 417

Query: 122 EVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLPEK 181
           + E+I ++ +E    + +I EL      QE++   +EE     +E+++  E   +   EK
Sbjct: 418 QDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEK 477

Query: 182 IPE 184
           I E
Sbjct: 478 IQE 480


>gi|221316642 nuclear distribution gene E homolog 1 [Homo sapiens]
          Length = 335

 Score = 43.9 bits (102), Expect = 9e-05
 Identities = 43/168 (25%), Positives = 82/168 (48%), Gaps = 12/168 (7%)

Query: 22  QLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKKKRYQEQLLDRTENQI 81
           +L++ ++  R+Y+  +  QL++     R LL +  + R +L   K++++ Q       QI
Sbjct: 35  ELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ-HSEGYRQI 93

Query: 82  SSLE-AMVQSIEFTQIEMKVMEGLQFGNECLN--KMHQVMSIEEVERILDETQEAVEY-Q 137
           S+LE  + Q+        K +  L+  N+ L   K   +MS+E+ E+ L++  E   + +
Sbjct: 94  SALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLE 153

Query: 138 RQIDE---LLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLPEKI 182
            ++DE   LL      +DE   L +  A+ Q+Q    E P  P+P  +
Sbjct: 154 SELDEKENLLESVQRLKDEARDLRQELAVQQKQ----EKPRTPMPSSV 197


>gi|8923110 nuclear distribution gene E homolog 1 [Homo sapiens]
          Length = 335

 Score = 43.9 bits (102), Expect = 9e-05
 Identities = 43/168 (25%), Positives = 82/168 (48%), Gaps = 12/168 (7%)

Query: 22  QLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKKKRYQEQLLDRTENQI 81
           +L++ ++  R+Y+  +  QL++     R LL +  + R +L   K++++ Q       QI
Sbjct: 35  ELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ-HSEGYRQI 93

Query: 82  SSLE-AMVQSIEFTQIEMKVMEGLQFGNECLN--KMHQVMSIEEVERILDETQEAVEY-Q 137
           S+LE  + Q+        K +  L+  N+ L   K   +MS+E+ E+ L++  E   + +
Sbjct: 94  SALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLE 153

Query: 138 RQIDE---LLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLPEKI 182
            ++DE   LL      +DE   L +  A+ Q+Q    E P  P+P  +
Sbjct: 154 SELDEKENLLESVQRLKDEARDLRQELAVQQKQ----EKPRTPMPSSV 197


>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
           sapiens]
          Length = 1268

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 46/186 (24%), Positives = 81/186 (43%), Gaps = 16/186 (8%)

Query: 9   KQSRVTEQDKAILQLKQQRDKLRQYQKR---IAQQLERE--RALARQLLRDGRKERAKLL 63
           K+  + E+ K I + K+QR +L + Q+R   + +Q ERE  R    Q+ R+  + RA+  
Sbjct: 384 KRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHE 443

Query: 64  LKKKRYQ---EQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSI 120
            + KR Q   ++  +R + Q+      + S++  + E + +E      + L    + MS 
Sbjct: 444 QEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVE-----KKPLYHYKEGMSP 498

Query: 121 EEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAIL---EELSAITQEQIELPEVPSEP 177
            E      E    V  + Q   L A     E     L   +E   +T  ++E+P   S+P
Sbjct: 499 SEKPAWAKEIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDP 558

Query: 178 LPEKIP 183
             E  P
Sbjct: 559 TSENPP 564


>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
           sapiens]
          Length = 1276

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 46/186 (24%), Positives = 81/186 (43%), Gaps = 16/186 (8%)

Query: 9   KQSRVTEQDKAILQLKQQRDKLRQYQKR---IAQQLERE--RALARQLLRDGRKERAKLL 63
           K+  + E+ K I + K+QR +L + Q+R   + +Q ERE  R    Q+ R+  + RA+  
Sbjct: 384 KRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHE 443

Query: 64  LKKKRYQ---EQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSI 120
            + KR Q   ++  +R + Q+      + S++  + E + +E      + L    + MS 
Sbjct: 444 QEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVE-----KKPLYHYKEGMSP 498

Query: 121 EEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAIL---EELSAITQEQIELPEVPSEP 177
            E      E    V  + Q   L A     E     L   +E   +T  ++E+P   S+P
Sbjct: 499 SEKPAWAKEIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDP 558

Query: 178 LPEKIP 183
             E  P
Sbjct: 559 TSENPP 564


>gi|203096856 kinesin family member 7 [Homo sapiens]
          Length = 1343

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 40/163 (24%), Positives = 77/163 (47%), Gaps = 22/163 (13%)

Query: 8   KKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKKK 67
           + + R+ E ++ +  ++QQ+ +L   Q+R+ ++ E++R L  ++ +  R+ R K L  K 
Sbjct: 816 QSEKRLQELERNVQLMRQQQGQL---QRRLREETEQKRRLEAEMSK--RQHRVKELELKH 870

Query: 68  RYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEEVERIL 127
             Q+++L             +++ E    + K   G    N  +  + Q   IEE ++ L
Sbjct: 871 EQQQKILK------------IKTEEIAAFQRKRRSG---SNGSVVSLEQQQKIEEQKKWL 915

Query: 128 DETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIEL 170
           D+  E V  QR+  E L         +AIL +  A+ QE+  L
Sbjct: 916 DQEMEKVLQQRRALEELGEEL--HKREAILAKKEALMQEKTGL 956


>gi|157785548 PAS domain containing 1 [Homo sapiens]
          Length = 773

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 38/174 (21%), Positives = 83/174 (47%), Gaps = 10/174 (5%)

Query: 7   RKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKK 66
           +++Q ++ EQ   + QL++QR   +Q + +  ++L+ ++   ++ L++ R+++ K L ++
Sbjct: 490 KEQQRQLREQ---LQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQER 546

Query: 67  KRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVM--SIEEVE 124
           K++Q Q+L +   +    E   Q ++   ++  V+ G +    CL     V         
Sbjct: 547 KKWQGQMLQKEPEE----EQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVSVPLCNHPV 602

Query: 125 RILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPL 178
           R L + Q  V  QR  ++  +G +  E+     +E  +   E  + P V   PL
Sbjct: 603 RFL-QAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQSFYPEAYQGPPVNQLPL 655


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 48/195 (24%), Positives = 87/195 (44%), Gaps = 5/195 (2%)

Query: 7   RKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKK 66
           R +Q    EQ++   QL ++ ++ R  Q+R  Q+L+RE+   R  L    +ER +  LK+
Sbjct: 533 RSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592

Query: 67  KRYQ--EQLLDRTE-NQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEEV 123
           ++ +  EQ L R E  ++   E   Q ++  + E +  + L    E   +  Q +  E+ 
Sbjct: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652

Query: 124 ERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIE--LPEVPSEPLPEK 181
           ER     +   E +R    L      +  E  + EE     +E+I+  +P+   +   E 
Sbjct: 653 ERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEA 712

Query: 182 IPENVPVKARPRQAE 196
                 V +RPR+ E
Sbjct: 713 DARQSKVYSRPRKQE 727



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 39/175 (22%), Positives = 90/175 (51%), Gaps = 8/175 (4%)

Query: 8    KKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKKK 67
            +K+ ++ ++++  LQ +++  + RQ Q+R  ++ E+ +    QLLR+ R++R +   +++
Sbjct: 900  RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959

Query: 68   RYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNE-CLNKMHQVMSIEEVERI 126
              +++ L + E Q+   E   +  +  + + +  E LQ   E  L +  +    +E ER 
Sbjct: 960  YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWER- 1018

Query: 127  LDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLPEK 181
              + ++  E Q++ ++LL     +E E   L+E     +E+ EL +   + L E+
Sbjct: 1019 --QYRKKDELQQEEEQLL----REEREKRRLQERERQYREEEELQQEEEQLLGEE 1067



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 44/179 (24%), Positives = 88/179 (49%), Gaps = 16/179 (8%)

Query: 7    RKKQSRVTEQDKAILQLKQQR---DKLRQYQKRIAQQLERERALARQLLRDGRKERAKLL 63
            RKK     E+++ + + +++R   ++ RQY++    Q E E     QLL + R+ R +  
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEE-----QLLGEERETRRRQE 1075

Query: 64   LKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNE-CLNKMHQVMSIEE 122
            L+++  +E+ L + E Q+   E   +  +  + + +  E LQ   E  L +  +    +E
Sbjct: 1076 LERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135

Query: 123  VERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLPEK 181
            +ER   + +E  E Q++ ++LL     +E E    +EL    +E+ EL +   + L E+
Sbjct: 1136 LER---QYREEEEVQQEEEQLL----REEPEKRRRQELERQYREEEELQQEEEQLLREE 1187



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 41/155 (26%), Positives = 70/155 (45%), Gaps = 19/155 (12%)

Query: 7   RKKQ-SRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQ--LLRDGRKERAKLL 63
           RK+Q  R  E+++    LK + ++ R+ Q+R  QQL RE+   R+  L R   +ER +  
Sbjct: 472 RKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQR 531

Query: 64  LKKKRY--------QEQLLDRTENQISSLEAMVQSIEFTQIEMK--------VMEGLQFG 107
           L+ ++         +EQLL R E +    E   Q ++  Q E +             +  
Sbjct: 532 LRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK 591

Query: 108 NECLNKMHQVMSIEEVERILDETQEAVEYQRQIDE 142
            E   ++ Q +  EEVER+  E +     +R+  E
Sbjct: 592 REQEERLEQRLKREEVERLEQEERREQRLKREEPE 626



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 38/160 (23%), Positives = 79/160 (49%), Gaps = 13/160 (8%)

Query: 8    KKQSRVTEQDKAILQLKQ----QRDKLRQYQKRIAQQLERERALARQLLRDGRKE--RAK 61
            ++Q R  EQ++   Q +     + ++L + +++ A++ +R+    +QLLR+ R+E  R +
Sbjct: 1273 EQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQ 1332

Query: 62   LLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIE 121
               +K R +EQLL   E Q   L    +  +F + E++  E    G + L +  ++   E
Sbjct: 1333 ETDRKFREEEQLLQEREEQ--PLRRQERDRKFREEELRHQEQ---GRKFLEEEQRLRRQE 1387

Query: 122  EVERILDETQE--AVEYQRQIDELLAGSFTQEDEDAILEE 159
               + L E Q+    E ++Q+ +     F +E++    +E
Sbjct: 1388 RERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQE 1427



 Score = 37.4 bits (85), Expect = 0.009
 Identities = 37/161 (22%), Positives = 78/161 (48%), Gaps = 11/161 (6%)

Query: 7   RKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALAR--------QLLRDGRKE 58
           R++Q R  +Q +   QL++++   R+ Q R  QQL RE+ L R        QL R+  +E
Sbjct: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE 432

Query: 59  RAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVM 118
           R +   +++R +++L    E +   L+   ++    Q   K  + L+   E   +  + +
Sbjct: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRK--QQLKRDQE-EERRERWL 489

Query: 119 SIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEE 159
            +EE ER   + +   + +R+ +E       +++E+  L++
Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530



 Score = 37.4 bits (85), Expect = 0.009
 Identities = 44/178 (24%), Positives = 82/178 (46%), Gaps = 20/178 (11%)

Query: 8    KKQSRVTEQDKAILQLKQQRD-KLRQYQKRIAQQLERERALARQLLRDGRKERAKLLL-- 64
            ++Q R  E+++   QL+Q RD K R+ ++++++Q ER+R    +  +  R+ER +  L  
Sbjct: 1396 EQQLRCQEREQ---QLRQDRDRKFREEEQQLSRQ-ERDRKFREEEQQVRRQERERKFLEE 1451

Query: 65   ---------KKKRYQEQLL-DRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKM 114
                     +K R +EQLL +R E Q+   E   + +E  Q   +     +F  + L   
Sbjct: 1452 EQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQ 1511

Query: 115  HQVMSIEEVERILDETQ---EAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIE 169
                   E E+ L   Q   + ++ ++Q+     G   ++D D    E   + QE+ E
Sbjct: 1512 EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE 1569



 Score = 36.2 bits (82), Expect = 0.019
 Identities = 40/159 (25%), Positives = 70/159 (44%), Gaps = 15/159 (9%)

Query: 7   RKKQSRVTEQDKAIL------QLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERA 60
           R+K+ +  E+++ +       QL+++ D L++ Q+R   Q +R     R  L + RK R 
Sbjct: 827 REKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRR 886

Query: 61  KLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSI 120
             L  K   QEQL  R E Q+   E      E  +   +  +  Q+  E      Q+   
Sbjct: 887 HTLYAKPALQEQL--RKEQQLLQEEEEELQREEREKRRRQEQERQYREE-----EQLQ-- 937

Query: 121 EEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEE 159
           +E E++L E +E    Q +  +       Q+ E+ +L E
Sbjct: 938 QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGE 976



 Score = 35.0 bits (79), Expect = 0.043
 Identities = 37/149 (24%), Positives = 74/149 (49%), Gaps = 16/149 (10%)

Query: 4    LFGRKKQSR----VTEQDKAILQLKQQRDKL--RQYQKRIAQQLERE-------RALARQ 50
            L G ++++R    +  Q +   +L+Q+ ++L   + +KR  Q+ ER+       +    Q
Sbjct: 1063 LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQ 1122

Query: 51   LLRDGRKERAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNEC 110
            LLR+ R++R +  L+++  +E+ + + E Q+   E   +  +  + + +  E LQ   E 
Sbjct: 1123 LLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQ 1182

Query: 111  LNKMHQVMSIEEVERILDETQEAVEYQRQ 139
            L +  Q    +E ER   + +E  E QRQ
Sbjct: 1183 LLREEQEKRRQERER---QYREEEELQRQ 1208



 Score = 34.7 bits (78), Expect = 0.056
 Identities = 34/165 (20%), Positives = 77/165 (46%), Gaps = 7/165 (4%)

Query: 7   RKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALAR--QLLRDGRKERAKLLL 64
           RK++    EQ +   + ++Q+++  Q ++R  QQL RE+   R  QL R+  +ER +  L
Sbjct: 308 RKQEEERREQQE---ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQL 364

Query: 65  KKKRYQEQLLD--RTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEE 122
           ++++ +E+     R E Q+   + + +  +  + +    E      + L +  Q+   ++
Sbjct: 365 RREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 424

Query: 123 VERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQ 167
           + R  +E +   +++++  E       +E  D +  E      EQ
Sbjct: 425 LRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQ 469



 Score = 34.3 bits (77), Expect = 0.073
 Identities = 42/190 (22%), Positives = 83/190 (43%), Gaps = 35/190 (18%)

Query: 7   RKKQSRVTEQDKAILQLKQ-QRDKLRQYQKRIAQQLERERALAR-QLLRDGRKERAKLLL 64
           R++++   EQ++   QLK+ Q ++ R+   ++ ++  RE+   R Q LR  ++ER +  L
Sbjct: 460 REEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRL 519

Query: 65  KKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEEVE 124
           K++  +E+L  R  ++                        Q   E   +  Q++  EE +
Sbjct: 520 KRQEEEERLQQRLRSE-----------------------QQLRREQEERREQLLKREEEK 556

Query: 125 RILDETQE---AVEYQRQIDELLAGS-------FTQEDEDAILEELSAITQEQIELPEVP 174
           R+  E +E     E + + D+LL            +E E+ + + L     E++E  E  
Sbjct: 557 RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERR 616

Query: 175 SEPLPEKIPE 184
            + L  + PE
Sbjct: 617 EQRLKREEPE 626



 Score = 33.5 bits (75), Expect = 0.12
 Identities = 37/161 (22%), Positives = 69/161 (42%), Gaps = 14/161 (8%)

Query: 6    GRKKQSRVTEQDKAILQLKQQ-------RDKLRQYQKRIAQQLERERALARQLLRDGRKE 58
            G ++Q R  E+D+   + +QQ       R  L++ Q+   Q+LER+     QL ++  +E
Sbjct: 1679 GEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE 1738

Query: 59   RAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVM 118
            + +   + ++  E+   R E +   L    +  +F + E    E  +   + L       
Sbjct: 1739 QLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREE---QQLRSQESDR 1795

Query: 119  SIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEE 159
               E E++  E +E     +Q D    G +  E+E   LEE
Sbjct: 1796 KFREEEQLRQEREEQQLRPQQRD----GKYRWEEEQLQLEE 1832



 Score = 32.3 bits (72), Expect = 0.28
 Identities = 32/136 (23%), Positives = 60/136 (44%), Gaps = 12/136 (8%)

Query: 7   RKKQSRVTEQDKAILQLK---QQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLL 63
           R+ + +  E+++A  Q +   Q+RD   Q+Q     +  R+R  AR  LR+ R+ + +  
Sbjct: 742 RESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAE 801

Query: 64  LKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEEV 123
            +++R Q  L +  E +    +   +  E   +E +         E L +  +   ++E 
Sbjct: 802 ERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE---------EQLQRRERAQQLQEE 852

Query: 124 ERILDETQEAVEYQRQ 139
           E  L E QE    Q Q
Sbjct: 853 EDGLQEDQERRRSQEQ 868



 Score = 32.3 bits (72), Expect = 0.28
 Identities = 57/234 (24%), Positives = 95/234 (40%), Gaps = 54/234 (23%)

Query: 7    RKKQSRVTEQDKAIL-------QLKQQRD-KLRQ----YQKRIAQQL------------- 41
            R++Q R   +D+  L       QL+Q+RD K R+     Q+R  QQL             
Sbjct: 1590 RQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEE 1649

Query: 42   ------ERERAL----------ARQLLRDGRKE--RAKLLLKKKRYQEQLLDRTENQISS 83
                  ERE+ L            QLL++G ++  R +   +K R +EQ L R E +   
Sbjct: 1650 PQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKF 1709

Query: 84   LEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEEVERILDETQEAVEYQRQIDEL 143
            L+   Q +   ++E K  E  Q   E   +  Q+   E   +IL+E Q   E + Q    
Sbjct: 1710 LQE-EQQLRRQELERKFREEEQLRQE--TEQEQLRRQERYRKILEEEQLRPEREEQ---- 1762

Query: 144  LAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLPEKIPENVPVKARPRQAEL 197
                  +++ D    E   + QE+ E  ++ S+    K  E   ++    + +L
Sbjct: 1763 ---QLRRQERDRKFREEEQLRQER-EEQQLRSQESDRKFREEEQLRQEREEQQL 1812



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 19/75 (25%), Positives = 47/75 (62%), Gaps = 2/75 (2%)

Query: 8   KKQSRVTEQDKAILQLKQQR-DKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKK 66
           ++Q  + E+++ + +L++Q   + RQ +++  Q+L RE+ L R+   + R+++ +   ++
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325

Query: 67  KRYQEQLLDRTENQI 81
           +R +EQ  +R E Q+
Sbjct: 326 ER-REQQEERREQQL 339



 Score = 29.6 bits (65), Expect = 1.8
 Identities = 15/74 (20%), Positives = 45/74 (60%)

Query: 7   RKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKK 66
           ++++ ++ + ++  L+ ++Q ++ +Q + R  QQL R++   R+  ++ R+E+ +   ++
Sbjct: 272 QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQ 331

Query: 67  KRYQEQLLDRTENQ 80
           +  +EQ L R + +
Sbjct: 332 EERREQQLRREQEE 345



 Score = 29.3 bits (64), Expect = 2.4
 Identities = 33/141 (23%), Positives = 70/141 (49%), Gaps = 21/141 (14%)

Query: 8    KKQSRVTEQDKAILQL---KQQRDKL-RQYQKRIAQQLERERALARQLLRDGRKERAKLL 63
            +++  V ++++ +L+    K++R +L RQY++    Q E E     QLLR+ +++R +  
Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEE-----QLLREEQEKRRQER 1195

Query: 64   LKKKRYQEQLLD-------RTENQISSLE-----AMVQSIEFTQIEMKVMEGLQFGNECL 111
             ++ R +E+L         R E+Q S L+         ++   ++  K  E  QF     
Sbjct: 1196 ERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED 1255

Query: 112  NKMHQVMSIEEVERILDETQE 132
            +++    S ++++ +L E QE
Sbjct: 1256 SQLRDRQSQQDLQHLLGEQQE 1276



 Score = 28.5 bits (62), Expect = 4.0
 Identities = 25/141 (17%), Positives = 69/141 (48%), Gaps = 9/141 (6%)

Query: 7   RKKQSRVTEQDKAI--------LQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKE 58
           RK+++ + ++++ +         +L+++ ++LR+ +++  ++  +E    +Q LR  ++ 
Sbjct: 247 RKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQL 306

Query: 59  RAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVM 118
           R K   +++  QE+  ++ E +    E   Q +   Q E +  + L+   E   +  Q+ 
Sbjct: 307 RRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQ-LRREQEEERREQQLR 365

Query: 119 SIEEVERILDETQEAVEYQRQ 139
             +E ER   + +   + +R+
Sbjct: 366 REQEEERREQQLRREQQLRRE 386



 Score = 28.5 bits (62), Expect = 4.0
 Identities = 35/136 (25%), Positives = 58/136 (42%), Gaps = 13/136 (9%)

Query: 24  KQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKKKRYQEQLLDRTENQISS 83
           +++R+K  Q+ +   Q   RERA   Q   DG +E      +++R QEQ  D+       
Sbjct: 824 RREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQ----ERRRSQEQRRDQKWRW--Q 877

Query: 84  LEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEEVERILDETQEAVEYQRQIDEL 143
           LE   +    T      ++      E L K  Q++  EE E +  E +E    Q Q  + 
Sbjct: 878 LEEERKRRRHTLYAKPALQ------EQLRKEQQLLQ-EEEEELQREEREKRRRQEQERQY 930

Query: 144 LAGSFTQEDEDAILEE 159
                 Q++E+ +L E
Sbjct: 931 REEEQLQQEEEQLLRE 946



 Score = 28.5 bits (62), Expect = 4.0
 Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 1/73 (1%)

Query: 9    KQSRVTEQDKAILQLK-QQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKKK 67
            ++     Q++   QL+ QQRD   ++++   Q  E+E+ L ++  R  R E      +K 
Sbjct: 1798 REEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKS 1857

Query: 68   RYQEQLLDRTENQ 80
            R +EQ L + E Q
Sbjct: 1858 RREEQELWQEEEQ 1870



 Score = 28.1 bits (61), Expect = 5.2
 Identities = 32/152 (21%), Positives = 65/152 (42%), Gaps = 16/152 (10%)

Query: 8   KKQSRVTEQDKAILQ------------LKQQRDKLR----QYQKRIAQQLERERALARQL 51
           K+Q R   QD+   +            L+++ +KL+    Q Q+ + ++ E+ R L RQ 
Sbjct: 226 KQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQE 285

Query: 52  LRDGRKERAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECL 111
           LR  R+E  +   + +R Q+    + E +    E   +  E  + + +  E      +  
Sbjct: 286 LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEE 345

Query: 112 NKMHQVMSIEEVERILDETQEAVEYQRQIDEL 143
            +  Q+   +E ER   + +   E +R+  +L
Sbjct: 346 RREQQLRREQEEERREQQLRREQEEERREQQL 377


>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
           sapiens]
          Length = 1133

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 34/145 (23%), Positives = 66/145 (45%), Gaps = 12/145 (8%)

Query: 7   RKKQSRVTEQDKAILQLKQQRDKLRQY-------QKRIAQQLERERALARQLLRDGRKER 59
           + ++ +  E++K +  LK++  KL+ +       Q+R+  QL  +R   ++L  + ++  
Sbjct: 212 KSQEEKEQEKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETH 271

Query: 60  AKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMS 119
            KL L + R QE+    T  +    E   Q+ +F Q +  +M  L   NE          
Sbjct: 272 TKLALAEARVQEEEQKATRLE---KELQTQTTKFHQDQDTIMAKLT--NEDSQNRQLQQK 326

Query: 120 IEEVERILDETQEAVEYQRQIDELL 144
           +  + R +DE +E     R+ +E L
Sbjct: 327 LAALSRQIDELEETNRSLRKAEEEL 351


>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
           sapiens]
          Length = 1135

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 34/145 (23%), Positives = 66/145 (45%), Gaps = 12/145 (8%)

Query: 7   RKKQSRVTEQDKAILQLKQQRDKLRQY-------QKRIAQQLERERALARQLLRDGRKER 59
           + ++ +  E++K +  LK++  KL+ +       Q+R+  QL  +R   ++L  + ++  
Sbjct: 212 KSQEEKEQEKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETH 271

Query: 60  AKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMS 119
            KL L + R QE+    T  +    E   Q+ +F Q +  +M  L   NE          
Sbjct: 272 TKLALAEARVQEEEQKATRLE---KELQTQTTKFHQDQDTIMAKLT--NEDSQNRQLQQK 326

Query: 120 IEEVERILDETQEAVEYQRQIDELL 144
           +  + R +DE +E     R+ +E L
Sbjct: 327 LAALSRQIDELEETNRSLRKAEEEL 351


>gi|94721321 coiled-coil domain containing 11 [Homo sapiens]
          Length = 514

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 40/154 (25%), Positives = 77/154 (50%), Gaps = 17/154 (11%)

Query: 16  QDKAILQLKQQRDKLRQ---YQKRIAQQLERERALARQLLRDGRKERAKLLLKK------ 66
           Q++A  + +++ D +R+   Y K +AQ+ E E+A  ++  R   +++AK L +K      
Sbjct: 322 QEEADKKKQKREDMIREQKIYHKYLAQRREEEKAQEKEFDRILEEDKAKKLAEKDKELRL 381

Query: 67  -KRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEEVER 125
            K  + QL+D     + + +  VQ  E  Q E K  E      + +N+  + ++ EE E 
Sbjct: 382 EKEARRQLVDEV---MCTRKLQVQ--EKLQREAKEQEERAMEQKHINESLKELNCEEKEN 436

Query: 126 ILDETQEAVEYQRQIDELLAGSFTQEDEDAILEE 159
                + A EY++Q+   +A  + Q+ ++A  EE
Sbjct: 437 FARRQRLAQEYRKQLQMQIA--YQQQSQEAEKEE 468


>gi|7706353 vacuolar protein sorting 24 isoform 1 [Homo sapiens]
          Length = 222

 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 43/190 (22%), Positives = 91/190 (47%), Gaps = 24/190 (12%)

Query: 8   KKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERA--LARQLLRDGRKERAKLLLK 65
           +K+ RV   D+ I  ++++ +K+++  K  A++ +++    LA++++R  RK  +KL   
Sbjct: 24  RKEMRVV--DRQIRDIQREEEKVKRSVKDAAKKGQKDVCIVLAKEMIRS-RKAVSKLYAS 80

Query: 66  KKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEEVER 125
           K      L+   +NQ++ L              +V   LQ   E +  M  ++ I E++ 
Sbjct: 81  KAHMNSVLMGM-KNQLAVL--------------RVAGSLQKSTEVMKAMQSLVKIPEIQA 125

Query: 126 ILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPL---PEKI 182
            + E  + +     I+E+L  +F   D+   +EE + +  ++I L E+ +  L   P K+
Sbjct: 126 TMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRI-LFEITAGALGKAPSKV 184

Query: 183 PENVPVKARP 192
            + +P    P
Sbjct: 185 TDALPEPEPP 194


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 35/167 (20%), Positives = 89/167 (53%), Gaps = 16/167 (9%)

Query: 10   QSRVTEQDKAILQLKQQRDKLR-QYQKRIAQQLERERALARQLLRDGRKERAKLLLKKKR 68
            + ++ +  K   +L+ Q+++++ + Q++  +  E+   L +QL  D +KE  + +L +K 
Sbjct: 955  EEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKS 1014

Query: 69   YQEQLLDRTENQISSLEAMVQSIEFTQIEMK-VMEGLQFGNECLNKMHQVMSIEEVERIL 127
            ++ +  D  E QI SL+  +++++  +++++ ++EG    ++ L          EV R+ 
Sbjct: 1015 FELKTQD-YEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLK--------AEVARLS 1065

Query: 128  DETQEAVEYQRQIDELLAGSF-----TQEDEDAILEELSAITQEQIE 169
             + +   E++++I+ L A         Q  +  + E++S IT++ +E
Sbjct: 1066 KQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLE 1112


>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
          Length = 1235

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 46/192 (23%), Positives = 89/192 (46%), Gaps = 34/192 (17%)

Query: 15   EQDKAILQLKQQR-DKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLK-KKRYQEQ 72
            +Q + I +L+Q+  ++LR   KRI  + E+E +  + +L++ +KE    + K  K  +++
Sbjct: 884  QQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKKEVINEVEKAPKELRKE 943

Query: 73   LLDRTENQISSLEAMVQSIEFTQIEMKVMEG-------------LQFGNECLNKMHQVMS 119
            L+ R + +++  +   Q  EF Q + + ++G                  ECLN   Q+M 
Sbjct: 944  LMKRRKEELAQSQ-HAQEQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMR 1002

Query: 120  IEEV------ERILDETQEAV------EYQRQIDELLAGSFTQEDE-----DAILEEL-S 161
              E       ER L E  + +      +Y  Q  +LL     + ++       ++EEL +
Sbjct: 1003 AREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKN 1062

Query: 162  AITQEQIELPEV 173
              TQE+  LP++
Sbjct: 1063 RQTQERARLPKI 1074


>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
          Length = 1139

 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 45/209 (21%), Positives = 95/209 (45%), Gaps = 39/209 (18%)

Query: 6   GRKKQSRVTEQDKAILQLKQQRDK--LRQYQKRIAQ---------QLERERALARQLLRD 54
           G + Q R  E+    L+LK+  DK  L++ +K   Q         +++ ++A  ++ L++
Sbjct: 85  GLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKE 144

Query: 55  GRKERAKLLLKKKRYQEQLLD-----------------RTENQISSLEAMVQSIE--FTQ 95
            RKE  + L  K+RY E++ D                 R E+    +EA+ + ++   T 
Sbjct: 145 ARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTD 204

Query: 96  IEMKVMEGLQFGNECLNKMHQVMSIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDA 155
           +E+   E  + G++     +Q+  +EE    L   ++A+   R +      S +++ E  
Sbjct: 205 LEILKAEIEEKGSDGAASSYQLKQLEEQNARL---KDALVRMRDL------SSSEKQEHV 255

Query: 156 ILEELSAITQEQIELPEVPSEPLPEKIPE 184
            L++L     +++E+     E L E++ +
Sbjct: 256 KLQKLMEKKNQELEVVRQQRERLQEELSQ 284


>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
          Length = 1253

 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 45/209 (21%), Positives = 95/209 (45%), Gaps = 39/209 (18%)

Query: 6   GRKKQSRVTEQDKAILQLKQQRDK--LRQYQKRIAQ---------QLERERALARQLLRD 54
           G + Q R  E+    L+LK+  DK  L++ +K   Q         +++ ++A  ++ L++
Sbjct: 199 GLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKE 258

Query: 55  GRKERAKLLLKKKRYQEQLLD-----------------RTENQISSLEAMVQSIE--FTQ 95
            RKE  + L  K+RY E++ D                 R E+    +EA+ + ++   T 
Sbjct: 259 ARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTD 318

Query: 96  IEMKVMEGLQFGNECLNKMHQVMSIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDA 155
           +E+   E  + G++     +Q+  +EE    L   ++A+   R +      S +++ E  
Sbjct: 319 LEILKAEIEEKGSDGAASSYQLKQLEEQNARL---KDALVRMRDL------SSSEKQEHV 369

Query: 156 ILEELSAITQEQIELPEVPSEPLPEKIPE 184
            L++L     +++E+     E L E++ +
Sbjct: 370 KLQKLMEKKNQELEVVRQQRERLQEELSQ 398


>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
          Length = 1144

 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 45/209 (21%), Positives = 95/209 (45%), Gaps = 39/209 (18%)

Query: 6   GRKKQSRVTEQDKAILQLKQQRDK--LRQYQKRIAQ---------QLERERALARQLLRD 54
           G + Q R  E+    L+LK+  DK  L++ +K   Q         +++ ++A  ++ L++
Sbjct: 85  GLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKE 144

Query: 55  GRKERAKLLLKKKRYQEQLLD-----------------RTENQISSLEAMVQSIE--FTQ 95
            RKE  + L  K+RY E++ D                 R E+    +EA+ + ++   T 
Sbjct: 145 ARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTD 204

Query: 96  IEMKVMEGLQFGNECLNKMHQVMSIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDA 155
           +E+   E  + G++     +Q+  +EE    L   ++A+   R +      S +++ E  
Sbjct: 205 LEILKAEIEEKGSDGAASSYQLKQLEEQNARL---KDALVRMRDL------SSSEKQEHV 255

Query: 156 ILEELSAITQEQIELPEVPSEPLPEKIPE 184
            L++L     +++E+     E L E++ +
Sbjct: 256 KLQKLMEKKNQELEVVRQQRERLQEELSQ 284


>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
          Length = 1278

 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 45/209 (21%), Positives = 95/209 (45%), Gaps = 39/209 (18%)

Query: 6   GRKKQSRVTEQDKAILQLKQQRDK--LRQYQKRIAQ---------QLERERALARQLLRD 54
           G + Q R  E+    L+LK+  DK  L++ +K   Q         +++ ++A  ++ L++
Sbjct: 219 GLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKE 278

Query: 55  GRKERAKLLLKKKRYQEQLLD-----------------RTENQISSLEAMVQSIE--FTQ 95
            RKE  + L  K+RY E++ D                 R E+    +EA+ + ++   T 
Sbjct: 279 ARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTD 338

Query: 96  IEMKVMEGLQFGNECLNKMHQVMSIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDA 155
           +E+   E  + G++     +Q+  +EE    L   ++A+   R +      S +++ E  
Sbjct: 339 LEILKAEIEEKGSDGAASSYQLKQLEEQNARL---KDALVRMRDL------SSSEKQEHV 389

Query: 156 ILEELSAITQEQIELPEVPSEPLPEKIPE 184
            L++L     +++E+     E L E++ +
Sbjct: 390 KLQKLMEKKNQELEVVRQQRERLQEELSQ 418


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 41/160 (25%), Positives = 79/160 (49%), Gaps = 12/160 (7%)

Query: 24  KQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKKKRYQEQL-LDRTENQIS 82
           +++R+K R+ +K + ++ E+ER   R+  R+ ++E+ K L K++  Q ++  +R + +  
Sbjct: 506 EREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEK 565

Query: 83  SLEAMVQSIEFTQIEMKVMEGLQFGNEC-LNKMHQVM--SIEEVERILDETQEAVEYQRQ 139
            LE   +  +  Q +MK  E      EC L K  + +   IE  E  L+   E  E +  
Sbjct: 566 ELERQKEKEKELQ-KMKEQE-----KECELEKEREKLEEKIEPREPNLEPMVEKQESENS 619

Query: 140 IDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLP 179
            ++     FT++D +   +E + +  E    PE  S+P P
Sbjct: 620 CNKEEEPVFTRQDSNRSEKEATPVVHE--TEPESGSQPRP 657



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 41/200 (20%), Positives = 87/200 (43%), Gaps = 24/200 (12%)

Query: 8   KKQSRVTEQDKAILQLKQ-QRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKK 66
           K++ R  E +K   Q ++ +R+K R+ Q+   ++LE+E+   R++ ++ ++E+ K L ++
Sbjct: 511 KEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQ 570

Query: 67  KRYQEQLLDRTENQ-----ISSLEAMVQSIEFTQIEMKVM-EGLQFGNECLNKMHQVMSI 120
           K  +++L    E +         E + + IE  +  ++ M E  +  N C  +   V + 
Sbjct: 571 KEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTR 630

Query: 121 EEVERILDETQEAVE-----------------YQRQIDELLAGSFTQEDEDAILEELSAI 163
           ++  R   E    V                  Y +Q  + L   F ++ E    ++    
Sbjct: 631 QDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ 690

Query: 164 TQEQIELPEVPSEPLPEKIP 183
            Q+ +    VPS+P    +P
Sbjct: 691 QQQGVLPQTVPSQPSSSTVP 710


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 35/173 (20%), Positives = 83/173 (47%), Gaps = 9/173 (5%)

Query: 9   KQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKKKR 68
           +++R  +++  + QL+QQ +  +Q Q    QQ +    L +Q  +DG+++ ++L  +K +
Sbjct: 80  EETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQ 139

Query: 69  --YQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQF----GNECLNKMHQVMSIEE 122
             + ++L    +      +   Q ++  Q   +  E LQ       + L +  Q+    +
Sbjct: 140 SVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQ 199

Query: 123 VERILDETQEAVEYQ---RQIDELLAGSFTQEDEDAILEELSAITQEQIELPE 172
            +++L + QE ++ Q   +Q ++L    F Q+ E    ++   + Q+Q +L +
Sbjct: 200 EQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQ 252



 Score = 34.7 bits (78), Expect = 0.056
 Identities = 51/223 (22%), Positives = 99/223 (44%), Gaps = 41/223 (18%)

Query: 10  QSRVTEQDKAILQLKQQRDKLRQYQKRIAQQ-----------------------LERERA 46
           Q +V EQ     QL QQ+ +  Q Q+ + QQ                       L+++  
Sbjct: 195 QQQVQEQ-----QLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQ 249

Query: 47  LARQLLRDGRKERAKLLLKKK--RYQEQLLDRTENQISS------LEAMVQSIEFTQIEM 98
           L +QLL+  + +  + LL+++  + Q+QLL + + Q+        L+   + ++  Q++ 
Sbjct: 250 LQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQP 309

Query: 99  KVMEGLQFGNECLNKMH-QVMSIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAIL 157
             +E  +     L  M   + S +E+E+   E +   E +RQ ++       QE+   + 
Sbjct: 310 PPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLE 369

Query: 158 EELSAITQEQIELPEVPSEPLPEKI---PENVPVKARPRQAEL 197
           ++L    Q+Q+E  EV  E  P ++    + V ++  P Q EL
Sbjct: 370 QQLEQ-QQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPEL 411



 Score = 33.1 bits (74), Expect = 0.16
 Identities = 29/167 (17%), Positives = 81/167 (48%), Gaps = 15/167 (8%)

Query: 8   KKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERAL--------ARQLLRDGRK-E 58
           ++Q R+ +Q + +   + Q  ++ Q Q+++ QQ++ ++ L         +QLL+   + +
Sbjct: 165 QEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQ 224

Query: 59  RAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVME--GLQFGNECLNKMHQ 116
           + +   ++++ Q+Q       Q   L+  +   +  Q++ +++E    Q   + L +  +
Sbjct: 225 QQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQE 284

Query: 117 VMSIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAI 163
            +  ++ +++L + QE ++ Q    +L       E+E+ +  EL  +
Sbjct: 285 QLQQQQQQQLLQQQQEQLQQQ----QLQPPPLEPEEEEEVELELMPV 327


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 38/182 (20%), Positives = 79/182 (43%), Gaps = 5/182 (2%)

Query: 10   QSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKKKRY 69
            ++RV E+++    L+ ++ K++Q  + + +QLE E +  ++L  +     AKL   KK  
Sbjct: 921  EARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKL---KKLE 977

Query: 70   QEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNEC--LNKMHQVMSIEEVERIL 127
            +EQ++   +N   + E  +      +    + E  +       L   H+ M  +  ER+ 
Sbjct: 978  EEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLR 1037

Query: 128  DETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLPEKIPENVP 187
             E ++  E ++   +L   S    D+ A L+   A  + Q+   E   +    ++ E   
Sbjct: 1038 REEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAA 1097

Query: 188  VK 189
             K
Sbjct: 1098 QK 1099



 Score = 35.4 bits (80), Expect = 0.033
 Identities = 46/200 (23%), Positives = 88/200 (44%), Gaps = 14/200 (7%)

Query: 8    KKQSRVTEQDKAILQLKQQRDKLR---QYQKRIAQQLERERALARQLLRDGRKERAKLLL 64
            +K +   + +K   +L+Q+ D L     +Q++ A  LE+++    QLL + +   AK   
Sbjct: 1403 EKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAE 1462

Query: 65   KKKRYQEQLLDRTENQISSL----EAMVQSIEFTQIEMKV---MEGLQFGNECLNKMHQV 117
            ++ R + +  ++    +S      EAM Q  E  ++  +    ME L    + + K   V
Sbjct: 1463 ERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGK--SV 1520

Query: 118  MSIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEP 177
              +E+ +R L+  Q+  E + Q++EL       ED    LE      + Q E      + 
Sbjct: 1521 HELEKSKRALE--QQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDE 1578

Query: 178  LPEKIPENVPVKARPRQAEL 197
              E+  + +  + R  +AEL
Sbjct: 1579 QSEEKKKQLVRQVREMEAEL 1598



 Score = 30.8 bits (68), Expect = 0.81
 Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 9/85 (10%)

Query: 9    KQSRVTEQD--KAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKK 66
            KQ R TE+     +LQ+  +R    QY+ +  +   R + L RQ L +  +E  +    +
Sbjct: 1835 KQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQ-LEEAEEEAQRANASR 1893

Query: 67   KRYQEQLLDRTE------NQISSLE 85
            ++ Q +L D TE       ++SSL+
Sbjct: 1894 RKLQRELEDATETADAMNREVSSLK 1918


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.334 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,525,252
Number of Sequences: 37866
Number of extensions: 281717
Number of successful extensions: 3755
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 164
Number of HSP's successfully gapped in prelim test: 453
Number of HSP's that attempted gapping in prelim test: 2367
Number of HSP's gapped (non-prelim): 1557
length of query: 201
length of database: 18,247,518
effective HSP length: 97
effective length of query: 104
effective length of database: 14,574,516
effective search space: 1515749664
effective search space used: 1515749664
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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