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Search of human proteins with 122937205
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937205 carcinoembryonic antigen-related cell adhesion
molecule 18 [Homo sapiens]
(398 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937205 carcinoembryonic antigen-related cell adhesion mole... 814 0.0
gi|40255013 carcinoembryonic antigen-related cell adhesion molec... 119 6e-27
gi|21314600 carcinoembryonic antigen-related cell adhesion molec... 117 2e-26
gi|68161541 carcinoembryonic antigen-related cell adhesion molec... 114 2e-25
gi|19923195 carcinoembryonic antigen-related cell adhesion molec... 114 2e-25
gi|98986445 carcinoembryonic antigen-related cell adhesion molec... 112 6e-25
gi|85861202 carcinoembryonic antigen-related cell adhesion molec... 104 1e-22
gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo sapi... 92 8e-19
gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo sapi... 92 8e-19
gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2 [... 89 5e-18
gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1... 85 1e-16
gi|5901930 carcinoembryonic antigen-related cell adhesion molecu... 85 1e-16
gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo sapi... 80 3e-15
gi|156564378 carcinoembryonic antigen-related cell adhesion mole... 80 4e-15
gi|156564393 carcinoembryonic antigen-related cell adhesion mole... 80 4e-15
gi|52317156 carcinoembryonic antigen-related cell adhesion molec... 74 2e-13
gi|148612793 carcinoembryonic antigen-related cell adhesion mole... 74 2e-13
gi|156564390 carcinoembryonic antigen-related cell adhesion mole... 74 2e-13
gi|156564388 carcinoembryonic antigen-related cell adhesion mole... 74 2e-13
gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [H... 69 7e-12
gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b [... 69 7e-12
gi|194328710 pregnancy specific beta-1-glycoprotein 8 isoform b ... 66 6e-11
gi|51510887 pregnancy specific beta-1-glycoprotein 8 isoform a [... 66 6e-11
gi|109240546 pregnancy specific beta-1-glycoprotein 3 [Homo sapi... 65 8e-11
gi|42560235 pregnancy specific beta-1-glycoprotein 4 isoform 1 [... 65 1e-10
gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens] 64 2e-10
gi|157805480 pregnancy specific beta-1-glycoprotein 7 precursor ... 57 3e-08
gi|156616284 pregnancy specific beta-1-glycoprotein 9 [Homo sapi... 55 1e-07
gi|121114300 carcinoembryonic antigen-related cell adhesion mole... 55 1e-07
gi|71143132 carcinoembryonic antigen-related cell adhesion molec... 54 2e-07
>gi|122937205 carcinoembryonic antigen-related cell adhesion
molecule 18 [Homo sapiens]
Length = 398
Score = 814 bits (2103), Expect = 0.0
Identities = 398/398 (100%), Positives = 398/398 (100%)
Query: 1 MEVSGCPTPAGQSAPWGGKAALKAGRRDRQPLCQETQVLEGAEEVAVSLEGPLLLEDPRQ 60
MEVSGCPTPAGQSAPWGGKAALKAGRRDRQPLCQETQVLEGAEEVAVSLEGPLLLEDPRQ
Sbjct: 1 MEVSGCPTPAGQSAPWGGKAALKAGRRDRQPLCQETQVLEGAEEVAVSLEGPLLLEDPRQ 60
Query: 61 LMDLSRPRWSLWRRVFLMASLLACGICQASGQIFITQTLGIKGYRTVVALDKVPEDVQEY 120
LMDLSRPRWSLWRRVFLMASLLACGICQASGQIFITQTLGIKGYRTVVALDKVPEDVQEY
Sbjct: 61 LMDLSRPRWSLWRRVFLMASLLACGICQASGQIFITQTLGIKGYRTVVALDKVPEDVQEY 120
Query: 121 SWYWGANDSAGNMIISHKPPSAQQPGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVVA 180
SWYWGANDSAGNMIISHKPPSAQQPGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVVA
Sbjct: 121 SWYWGANDSAGNMIISHKPPSAQQPGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVVA 180
Query: 181 GNETQRATGWLEVLELGSNLGISVNASSLVENMDSVAADCLTNVTNITWYVNDVPTSSSD 240
GNETQRATGWLEVLELGSNLGISVNASSLVENMDSVAADCLTNVTNITWYVNDVPTSSSD
Sbjct: 181 GNETQRATGWLEVLELGSNLGISVNASSLVENMDSVAADCLTNVTNITWYVNDVPTSSSD 240
Query: 241 RMTISPDGKTLVILRVSRYDRTIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDF 300
RMTISPDGKTLVILRVSRYDRTIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDF
Sbjct: 241 RMTISPDGKTLVILRVSRYDRTIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDF 300
Query: 301 NGIVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVE 360
NGIVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVE
Sbjct: 301 NGIVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVE 360
Query: 361 NPVTQLIMYMDVRIQAPHECSSSPPGSCFAHLPASMPC 398
NPVTQLIMYMDVRIQAPHECSSSPPGSCFAHLPASMPC
Sbjct: 361 NPVTQLIMYMDVRIQAPHECSSSPPGSCFAHLPASMPC 398
>gi|40255013 carcinoembryonic antigen-related cell adhesion molecule
6 (non-specific cross reacting antigen) [Homo sapiens]
Length = 344
Score = 119 bits (297), Expect = 6e-27
Identities = 90/302 (29%), Positives = 140/302 (46%), Gaps = 15/302 (4%)
Query: 72 WRRVFLMASLLACGICQASGQIFITQTLG--IKGYRTVVALDKVPEDVQEYSWYWGANDS 129
W+ V L ASLL + ++ I T +G ++ +P++ YSWY G
Sbjct: 15 WKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQNRIGYSWYKGERVD 74
Query: 130 AGNMIISHKPPSAQQ-PGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVVAGN-ETQRA 187
++I+ + + Q PGP Y+GRE + SLLI+ NDTG YT++V+ + + A
Sbjct: 75 GNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEA 134
Query: 188 TGWLEVLELGSNLGISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSDRMTIS 245
TG V IS N S+ VE+ D+VA C V N T W+VN S R+ +S
Sbjct: 135 TGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWVNGQSLPVSPRLQLS 194
Query: 246 PDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNGIV 304
TL +L V R D + +C I++ P RS+ ++L V YGPD + + ++
Sbjct: 195 NGNMTLTLLSVKRNDAGSYECEIQN-PASANRSDPVTLNVLYGPDGPTISPSKANYRP-- 251
Query: 305 TAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENPVT 364
G + + C S +Y W NG+ S ++ + ++ G Y C N T
Sbjct: 252 ----GENLNLSCHAASNPPAQYSWFINGTFQQ-STQELFIPNITVNNSGSYMCQAHNSAT 306
Query: 365 QL 366
L
Sbjct: 307 GL 308
>gi|21314600 carcinoembryonic antigen-related cell adhesion molecule
8 [Homo sapiens]
Length = 349
Score = 117 bits (292), Expect = 2e-26
Identities = 90/305 (29%), Positives = 143/305 (46%), Gaps = 16/305 (5%)
Query: 68 RWSL-WRRVFLMASLLACGICQASGQIFI--TQTLGIKGYRTVVALDKVPEDVQEYSWYW 124
RW + W+ + L ASL + Q+ I + +G ++ + +P+D + Y+WY
Sbjct: 10 RWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQDPRGYNWYK 69
Query: 125 GANDSAGNMIISHKPPSAQ-QPGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVVAGN- 182
G A II + + Q PGP Y+ RE + SLL+R NDTG+YT++V+ N
Sbjct: 70 GETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSYTLQVIKLNL 129
Query: 183 ETQRATGWLEVLELGSNLGISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSD 240
++ TG V IS N S+ VE+ D+VA C N T W+VN S
Sbjct: 130 MSEEVTGQFSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSP 189
Query: 241 RMTISPDGKTLVILRVSRYD-RTIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDD 299
R+ +S +TL +L V+R D +C I++ P S+ ++L V YGPD + +P D
Sbjct: 190 RLQLSNGNRTLTLLSVTRNDVGPYECEIQN-PASANFSDPVTLNVLYGPDAPTI--SPSD 246
Query: 300 FNGIVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTV 359
G + + C S +Y W NG+ ++ K+ + ++ + G Y C
Sbjct: 247 ----TYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQ-KLFIPNITTKNSGSYACHT 301
Query: 360 ENPVT 364
N T
Sbjct: 302 TNSAT 306
>gi|68161541 carcinoembryonic antigen-related cell adhesion molecule
1 isoform 2 precursor [Homo sapiens]
Length = 464
Score = 114 bits (285), Expect = 2e-25
Identities = 88/301 (29%), Positives = 143/301 (47%), Gaps = 17/301 (5%)
Query: 72 WRRVFLMASLLACGICQASGQIFITQTLGI---KGYRTVVALDKVPEDVQEYSWYWGAND 128
W+ + L ASLL + Q+ T+++ +G ++ + +P+ + YSWY G
Sbjct: 15 WQGLLLTASLLTFWNPPTTAQL-TTESMPFNVAEGKEVLLLVHNLPQQLFGYSWYKGERV 73
Query: 129 SAGNMIISHKPPSAQQ-PGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVVAGN-ETQR 186
I+ + + Q PGP +GRE + SLLI+ NDTG YT++V+ + +
Sbjct: 74 DGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEE 133
Query: 187 ATGWLEVLELGSNLGISVNASSLVENMDSVAADC--LTNVTNITWYVNDVPTSSSDRMTI 244
ATG V IS N S+ VE+ D+VA C T T W++N+ S R+ +
Sbjct: 134 ATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQL 193
Query: 245 SPDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNGI 303
S +TL +L V+R D +C I++ P RS+ ++L V YGPD + +P D
Sbjct: 194 SNGNRTLTLLSVTRNDTGPYECEIQN-PVSANRSDPVTLNVTYGPDTPTI--SPSD---- 246
Query: 304 VTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENPV 363
G+ + + C S +Y W+ NG+ S ++ + ++ G Y C N V
Sbjct: 247 TYYRPGANLSLSCYAASNPPAQYSWLINGTFQQ-STQELFIPNITVNNSGSYTCHANNSV 305
Query: 364 T 364
T
Sbjct: 306 T 306
Score = 39.3 bits (90), Expect = 0.006
Identities = 42/136 (30%), Positives = 62/136 (45%), Gaps = 13/136 (9%)
Query: 161 LLIRPTALNDTGNYTVR----VVAGNETQRATGWLEVLELGSNLG---ISVNASSLVENM 213
L I +N++G+YT V N T T + V EL + I + +++ +
Sbjct: 284 LFIPNITVNNSGSYTCHANNSVTGCNRTTVKT--IIVTELSPVVAKPQIKASKTTVTGDK 341
Query: 214 DSVAADCLTNVTNIT--WYVNDVPTSSSDRMTISPDGKTLVILRVSRYDR-TIQCMIESF 270
DSV C TN T I+ W+ + SS+RM +S TL I V R D T C + +
Sbjct: 342 DSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFN- 400
Query: 271 PEIFQRSERISLTVAY 286
P +S+ I L V Y
Sbjct: 401 PISKNQSDPIMLNVNY 416
>gi|19923195 carcinoembryonic antigen-related cell adhesion molecule
1 isoform 1 precursor [Homo sapiens]
Length = 526
Score = 114 bits (285), Expect = 2e-25
Identities = 88/301 (29%), Positives = 143/301 (47%), Gaps = 17/301 (5%)
Query: 72 WRRVFLMASLLACGICQASGQIFITQTLGI---KGYRTVVALDKVPEDVQEYSWYWGAND 128
W+ + L ASLL + Q+ T+++ +G ++ + +P+ + YSWY G
Sbjct: 15 WQGLLLTASLLTFWNPPTTAQL-TTESMPFNVAEGKEVLLLVHNLPQQLFGYSWYKGERV 73
Query: 129 SAGNMIISHKPPSAQQ-PGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVVAGN-ETQR 186
I+ + + Q PGP +GRE + SLLI+ NDTG YT++V+ + +
Sbjct: 74 DGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEE 133
Query: 187 ATGWLEVLELGSNLGISVNASSLVENMDSVAADC--LTNVTNITWYVNDVPTSSSDRMTI 244
ATG V IS N S+ VE+ D+VA C T T W++N+ S R+ +
Sbjct: 134 ATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQL 193
Query: 245 SPDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNGI 303
S +TL +L V+R D +C I++ P RS+ ++L V YGPD + +P D
Sbjct: 194 SNGNRTLTLLSVTRNDTGPYECEIQN-PVSANRSDPVTLNVTYGPDTPTI--SPSD---- 246
Query: 304 VTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENPV 363
G+ + + C S +Y W+ NG+ S ++ + ++ G Y C N V
Sbjct: 247 TYYRPGANLSLSCYAASNPPAQYSWLINGTFQQ-STQELFIPNITVNNSGSYTCHANNSV 305
Query: 364 T 364
T
Sbjct: 306 T 306
Score = 39.3 bits (90), Expect = 0.006
Identities = 42/136 (30%), Positives = 62/136 (45%), Gaps = 13/136 (9%)
Query: 161 LLIRPTALNDTGNYTVR----VVAGNETQRATGWLEVLELGSNLG---ISVNASSLVENM 213
L I +N++G+YT V N T T + V EL + I + +++ +
Sbjct: 284 LFIPNITVNNSGSYTCHANNSVTGCNRTTVKT--IIVTELSPVVAKPQIKASKTTVTGDK 341
Query: 214 DSVAADCLTNVTNIT--WYVNDVPTSSSDRMTISPDGKTLVILRVSRYDR-TIQCMIESF 270
DSV C TN T I+ W+ + SS+RM +S TL I V R D T C + +
Sbjct: 342 DSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFN- 400
Query: 271 PEIFQRSERISLTVAY 286
P +S+ I L V Y
Sbjct: 401 PISKNQSDPIMLNVNY 416
>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
5 preproprotein [Homo sapiens]
Length = 702
Score = 112 bits (280), Expect = 6e-25
Identities = 88/306 (28%), Positives = 134/306 (43%), Gaps = 14/306 (4%)
Query: 68 RWSL-WRRVFLMASLLACGICQASGQIFITQTLG--IKGYRTVVALDKVPEDVQEYSWYW 124
RW + W+R+ L ASLL + ++ I T +G ++ + +P+ + YSWY
Sbjct: 10 RWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFGYSWYK 69
Query: 125 GANDSAGNMIISHKPPSAQQ-PGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVVAGN- 182
G II + + Q PGP Y+GRE + SLLI+ NDTG YT+ V+ +
Sbjct: 70 GERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHVIKSDL 129
Query: 183 ETQRATGWLEVLELGSNLGISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSD 240
+ ATG V IS N S VE+ D+VA C + T W+VN+ S
Sbjct: 130 VNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSP 189
Query: 241 RMTISPDGKTLVILRVSRYDRTIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDF 300
R+ +S +TL + V+R D P +RS+ + L V YGPD + +
Sbjct: 190 RLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSY 249
Query: 301 NGIVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVE 360
G + + C S +Y W NG+ S ++ + ++ G Y C
Sbjct: 250 RS------GENLNLSCHAASNPPAQYSWFVNGTFQQ-STQELFIPNITVNNSGSYTCQAH 302
Query: 361 NPVTQL 366
N T L
Sbjct: 303 NSDTGL 308
Score = 62.0 bits (149), Expect = 9e-10
Identities = 55/208 (26%), Positives = 94/208 (45%), Gaps = 17/208 (8%)
Query: 161 LLIRPTALNDTGNYTVRV----VAGNETQRATGWLEVLELGSNLGISVNASSLVENMDSV 216
L I +N++G+YT + N T T + V I+ N S+ VE+ D+V
Sbjct: 284 LFIPNITVNNSGSYTCQAHNSDTGLNRTTVTT--ITVYAEPPKPFITSNNSNPVEDEDAV 341
Query: 217 AADCLTNVTNIT--WYVNDVPTSSSDRMTISPDGKTLVILRVSRYD-RTIQCMIESFPEI 273
A C + N T W+VN+ S R+ +S D +TL +L V+R D +C I++ +
Sbjct: 342 ALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSV 401
Query: 274 FQRSERISLTVAYGPDYVLLRSNPDDFNGIVTAEIGSQVEMECICYSFLDLKYHWIHNGS 333
S+ + L V YGPD +P G + + C S +Y W+ +G+
Sbjct: 402 -DHSDPVILNVLYGPD------DPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGN 454
Query: 334 LLNFSDAKMNLSSLAWEQMGRYRCTVEN 361
+ + ++ +S++ + G Y C N
Sbjct: 455 IQQHTQ-ELFISNITEKNSGLYTCQANN 481
Score = 58.5 bits (140), Expect = 1e-08
Identities = 50/166 (30%), Positives = 75/166 (45%), Gaps = 11/166 (6%)
Query: 202 ISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSDRMTISPDGKTLVILRVSRY 259
IS N S VE+ D+VA C N T W+VN S R+ +S +TL + V+R
Sbjct: 505 ISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRN 564
Query: 260 D-RTIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNGIVTAEIGSQVEMECIC 318
D R C I++ RS+ ++L V YGPD ++ S PD + G+ + + C
Sbjct: 565 DARAYVCGIQNSVSA-NRSDPVTLDVLYGPDTPII-SPPDS-----SYLSGANLNLSCHS 617
Query: 319 YSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENPVT 364
S +Y W NG + + ++ + G Y C V N T
Sbjct: 618 ASNPSPQYSWRINGIPQQHTQV-LFIAKITPNNNGTYACFVSNLAT 662
>gi|85861202 carcinoembryonic antigen-related cell adhesion molecule
16 [Homo sapiens]
Length = 484
Score = 104 bits (260), Expect = 1e-22
Identities = 80/307 (26%), Positives = 139/307 (45%), Gaps = 9/307 (2%)
Query: 68 RWSLWRRVFLMASLLACGICQASGQIFIT--QTLGIKGYRTVVALDKVPEDVQEYSWYWG 125
RWS LL+ +I IT +G + + + ++ YSWY G
Sbjct: 56 RWSFMALTGYSWLLLSATFLNVGAEISITLEPAQPSEGDNVTLVVHGLSGELLAYSWYAG 115
Query: 126 ANDSAGNMIISHKPPSAQQ-PGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVVAGN-E 183
S ++ S+ + + PGP +TGRE V +GSL I+ +G Y ++ +
Sbjct: 116 PTLSVSYLVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQ 175
Query: 184 TQRATGWLEVLELGSNLGISVNASSLVENMDSVAADCLTN--VTNITWYVNDVPTSSSDR 241
T+ G ++V E+ + + N+++LVE D++ C + + W+ N + R
Sbjct: 176 TEVGYGHVQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALR 235
Query: 242 MTISPDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDF 300
+ +SPDG+ L + R + QC + + P RSE I+LTV +GP+ V + +
Sbjct: 236 LGLSPDGRVLARHGIRREEAGAYQCEVWN-PVSVSRSEPINLTVYFGPERVAILQDSTTR 294
Query: 301 NGI-VTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTV 359
G + + + + + C+ S + +Y W NG L +N+SS+ Q G Y C
Sbjct: 295 TGCTIKVDFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIA 354
Query: 360 ENPVTQL 366
+N T L
Sbjct: 355 KNTKTLL 361
Score = 49.7 bits (117), Expect = 5e-06
Identities = 35/101 (34%), Positives = 50/101 (49%), Gaps = 11/101 (10%)
Query: 98 TLGIKGYRTVVALDKVPEDVQEYSWYWGANDSAGNMIISHKPPSAQQPGPMYTGRERVNR 157
TL ++GY P+D+ Y+WY G S N ++S P GP +TGRE
Sbjct: 394 TLTVQGY---------PKDLLVYAWYRGP-ASEPNRLLSQLPSGTWIAGPAHTGREVGFP 443
Query: 158 EGSLLIRPTALNDTGNYTVR-VVAGNETQRATGWLEVLELG 197
SLL++ L DTG YT++ V +T+ L+V LG
Sbjct: 444 NCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQVAPLG 484
>gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo
sapiens]
Length = 335
Score = 92.0 bits (227), Expect = 8e-19
Identities = 87/319 (27%), Positives = 139/319 (43%), Gaps = 23/319 (7%)
Query: 72 WRRVFLMASLLACGICQASGQIFITQTLGIK---GYRTVVALDKVPEDVQEYSWYWGAND 128
W+ + L ASLL + Q+ I + L K G ++ + +P+++ Y WY G
Sbjct: 15 WKGLLLTASLLNFWNLPITAQVTI-EALPPKVSEGKDVLLLVHNLPQNLAGYIWYKGQLM 73
Query: 129 SAGNMIISHKPPSAQQP-GPMYTGRERVNREGSLLIRPTALNDTGNYTVRVV-AGNETQR 186
+ I S+ GP YTGRE V SLLI+ D G+YT+ ++ G+ T+
Sbjct: 74 DLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSYTLHIIKRGDRTRG 133
Query: 187 ATGWLE---VLELGSNLGISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSDR 241
TG+ L+L I++N S EN D +A C N T W++N S R
Sbjct: 134 VTGYFTFNLYLKLPKPY-ITINNSKPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPR 192
Query: 242 MTISPDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDF 300
+ + + L++ V+R + +C I + RS+ ++L V YGPD P +
Sbjct: 193 VKRPIENRILILPSVTRNETGPYECEIRD-RDGGMRSDPVTLNVLYGPDL------PSIY 245
Query: 301 NGIVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVE 360
G + + C S +Y W NG S K+++ + + G Y C+V
Sbjct: 246 PSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQ-SGQKLSIPQITTKHRGLYTCSVR 304
Query: 361 NPVT--QLIMYMDVRIQAP 377
N T + M V + AP
Sbjct: 305 NSATGKESSKSMTVEVSAP 323
>gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo
sapiens]
Length = 335
Score = 92.0 bits (227), Expect = 8e-19
Identities = 87/319 (27%), Positives = 139/319 (43%), Gaps = 23/319 (7%)
Query: 72 WRRVFLMASLLACGICQASGQIFITQTLGIK---GYRTVVALDKVPEDVQEYSWYWGAND 128
W+ + L ASLL + Q+ I + L K G ++ + +P+++ Y WY G
Sbjct: 15 WKGLLLTASLLNFWNLPITAQVTI-EALPPKVSEGKDVLLLVHNLPQNLAGYIWYKGQLM 73
Query: 129 SAGNMIISHKPPSAQQP-GPMYTGRERVNREGSLLIRPTALNDTGNYTVRVV-AGNETQR 186
+ I S+ GP YTGRE V SLLI+ D G+YT+ ++ G+ T+
Sbjct: 74 DLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSYTLHIIKRGDRTRG 133
Query: 187 ATGWLE---VLELGSNLGISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSDR 241
TG+ L+L I++N S EN D +A C N T W++N S R
Sbjct: 134 VTGYFTFNLYLKLPKPY-ITINNSKPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPR 192
Query: 242 MTISPDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDF 300
+ + + L++ V+R + +C I + RS+ ++L V YGPD P +
Sbjct: 193 VKRPIENRILILPSVTRNETGPYECEIRD-RDGGMRSDPVTLNVLYGPDL------PSIY 245
Query: 301 NGIVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVE 360
G + + C S +Y W NG S K+++ + + G Y C+V
Sbjct: 246 PSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQ-SGQKLSIPQITTKHRGLYTCSVR 304
Query: 361 NPVT--QLIMYMDVRIQAP 377
N T + M V + AP
Sbjct: 305 NSATGKESSKSMTVEVSAP 323
>gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2
[Homo sapiens]
Length = 326
Score = 89.4 bits (220), Expect = 5e-18
Identities = 79/302 (26%), Positives = 133/302 (44%), Gaps = 17/302 (5%)
Query: 72 WRRVFLMASLLACGICQASGQIFI-TQTLGI-KGYRTVVALDKVPEDVQEYSWYWGANDS 129
W+ V L ASLL + Q+ I Q + +G ++ + +P+++ Y WY G
Sbjct: 15 WKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLAGYIWYKGQMTY 74
Query: 130 AGNMIISHKPPSAQQP-GPMYTGRERVNREGSLLIRPTALNDTGNYTVRVVAGNE-TQRA 187
+ I S+ + GP Y+GRERV SLLI+ D G+YT+ ++ + T
Sbjct: 75 LYHYITSYVVDGQRIIYGPAYSGRERVYSNASLLIQNVTQEDAGSYTLHIIKRRDGTGGV 134
Query: 188 TGWLEVLELGSNLGISVNASSL--VENMDSVAADC--LTNVTNITWYVNDVPTSSSDRMT 243
TG S+++S+L E M++V C T + W++N + R+
Sbjct: 135 TGHFTFTLHLETPKPSISSSNLNPREAMEAVILTCDPATPAASYQWWMNGQSLPMTHRLQ 194
Query: 244 ISPDGKTLVILRVSRY-DRTIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNG 302
+S +TL I V++Y +C I + P RS+ ++L + +GPD P +
Sbjct: 195 LSKTNRTLFIFGVTKYIAGPYECEIRN-PVSASRSDPVTLNLLHGPDL------PSIYPS 247
Query: 303 IVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENP 362
G + + C S +Y W NG S K+++ + + G Y C+V N
Sbjct: 248 FTYYRSGENLYLSCFAESNPRAQYSWTINGK-FQLSGQKLSIPQITTKHSGLYACSVRNS 306
Query: 363 VT 364
T
Sbjct: 307 AT 308
>gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1
[Homo sapiens]
Length = 335
Score = 85.1 bits (209), Expect = 1e-16
Identities = 79/317 (24%), Positives = 140/317 (44%), Gaps = 19/317 (5%)
Query: 72 WRRVFLMASLLACGICQASGQIFI-TQTLGI-KGYRTVVALDKVPEDVQEYSWYWGANDS 129
W+ + L A LL + Q+ I Q + +G ++ + +P+++ Y WY G
Sbjct: 15 WKGLLLTALLLNFWNLPTTAQVMIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74
Query: 130 AGNMIISHKPPSAQQP-GPMYTGRERVNREGSLLIRPTALNDTGNYTVRVV-AGNETQRA 187
+ I S+ GP Y+GRE V SLLI+ D G+YT+ ++ G+ T+
Sbjct: 75 LYHYITSYVVDGQIIIYGPAYSGRETVYSNASLLIQNVTREDAGSYTLHIIKRGDGTRGV 134
Query: 188 TGWLEVLELGSNLGISVNASSL--VENMDSVAADC--LTNVTNITWYVNDVPTSSSDRMT 243
TG+ S+++S+L E M++V C T + W++N + RM
Sbjct: 135 TGYFTFTLYLETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQ 194
Query: 244 ISPDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNG 302
+S +TL + V++Y +C I + RS+ ++L + +GPD P F
Sbjct: 195 LSETNRTLFLFGVTKYTAGPYECEIWNSGSA-SRSDPVTLNLLHGPDL------PRIFPS 247
Query: 303 IVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENP 362
+ + G +++ C S +Y W NG S K+ + + + G Y C+ N
Sbjct: 248 VTSYYSGENLDLSCFANSNPPAQYSWTINGK-FQLSGQKLFIPQITPKHNGLYACSARNS 306
Query: 363 VT--QLIMYMDVRIQAP 377
T + + +R+ AP
Sbjct: 307 ATGEESSTSLTIRVIAP 323
>gi|5901930 carcinoembryonic antigen-related cell adhesion molecule
7 [Homo sapiens]
Length = 265
Score = 85.1 bits (209), Expect = 1e-16
Identities = 67/223 (30%), Positives = 104/223 (46%), Gaps = 9/223 (4%)
Query: 72 WRRVFLMASLLACGICQASGQ--IFITQTLGIKGYRTVVALDKVPEDVQEYSWYWGANDS 129
W+ + L ASLL S Q I + +G ++ + +++ Y+WY G
Sbjct: 15 WQGLLLTASLLTFWNLPNSAQTNIDVVPFNVAEGKEVLLVVHNESQNLYGYNWYKGERVH 74
Query: 130 AGNMIISHKPPSAQQ--PGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVVAGN-ETQR 186
A II + +Q+ PGP + GRE + G+LLI+ ND G YT+ V+ N +
Sbjct: 75 ANYRIIGYVKNISQENAPGPAHNGRETIYPNGTLLIQNVTHNDAGFYTLHVIKENLVNEE 134
Query: 187 ATGWLEVLELGSNLGISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSDRMTI 244
T V I+ N + VEN D V C N T W+VN+ S R+ +
Sbjct: 135 VTRQFYVFSEPPKPSITSNNFNPVENKDIVVLTCQPETQNTTYLWWVNNQSLLVSPRLLL 194
Query: 245 SPDGKTLVILRVSRYD-RTIQCMIESFPEIFQRSERISLTVAY 286
S D +TLV+L ++ D +C I++ P RS+ ++L V Y
Sbjct: 195 STDNRTLVLLSATKNDIGPYECEIQN-PVGASRSDPVTLNVRY 236
>gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo
sapiens]
Length = 335
Score = 80.1 bits (196), Expect = 3e-15
Identities = 77/302 (25%), Positives = 133/302 (44%), Gaps = 17/302 (5%)
Query: 72 WRRVFLMASLLACGICQASGQIFI-TQTLGI-KGYRTVVALDKVPEDVQEYSWYWGANDS 129
W+ + + ASLL + Q+ I Q + +G ++ + +P+++ Y WY G
Sbjct: 15 WKGLLVTASLLNFWNLPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74
Query: 130 AGNMIISHKPPSAQQP-GPMYTGRERVNREGSLLIRPTALNDTGNYTVRVV-AGNETQRA 187
+ I S+ GP Y+GRE SLLI+ D G+YT+ ++ G+ T+
Sbjct: 75 LYHYITSYVVDGQIIIYGPAYSGRETAYSNASLLIQNVTREDAGSYTLHIIKRGDGTRGV 134
Query: 188 TGWLEVLELGSNLGISVNASSL--VENMDSVAADC--LTNVTNITWYVNDVPTSSSDRMT 243
TG+ S+++S+L E M++V C T T+ W++N + R
Sbjct: 135 TGYFTFTLYLETPKPSISSSNLNPREAMETVILTCDPETPDTSYQWWMNGQSLPMTHRFQ 194
Query: 244 ISPDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNG 302
+S +TL + V++Y +C I + RS+ ++L + +GPD L R +P N
Sbjct: 195 LSETNRTLFLFGVTKYTAGPYECEIRNSGSA-SRSDPVTLNLLHGPD--LPRIHPSYTN- 250
Query: 303 IVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENP 362
G + + C S +Y W NG S + + + + G Y C+V N
Sbjct: 251 ---YRSGDNLYLSCFANSNPPAQYSWTINGKFQQ-SGQNLFIPQITTKHSGLYVCSVRNS 306
Query: 363 VT 364
T
Sbjct: 307 AT 308
>gi|156564378 carcinoembryonic antigen-related cell adhesion
molecule 20 5L [Homo sapiens]
Length = 596
Score = 79.7 bits (195), Expect = 4e-15
Identities = 64/222 (28%), Positives = 99/222 (44%), Gaps = 20/222 (9%)
Query: 166 TALNDTGNYTVRVVAGNETQRATGWLEVLELGSNLGISVNASSLVENMDSVAADCLT--N 223
T L+ G VRV LE L + + S+N LVEN SV C T
Sbjct: 237 THLSSLGTLKVRV------------LETLTMPQVVPSSLN---LVENARSVDLTCQTVNQ 281
Query: 224 VTNITWYVNDVPTSSSDRMTISPDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISL 282
N+ W+++ P S+ + +S D +TL+I + R D C + ++ RSE + L
Sbjct: 282 SVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSR-ARSEPLEL 340
Query: 283 TVAYGPDYV-LLRSNPDDFNGIVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFSDAK 341
T+ YGPD V + R + + + AE+ S + ++C S +Y W S +
Sbjct: 341 TINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQ 400
Query: 342 MNLSSLAWEQMGRYRCTVENPVTQLIMYMDVRIQAPHECSSS 383
+ + +L WE G Y CT N +T L V ++ SSS
Sbjct: 401 LIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQSSS 442
Score = 73.9 bits (180), Expect = 2e-13
Identities = 56/169 (33%), Positives = 78/169 (46%), Gaps = 5/169 (2%)
Query: 202 ISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSDRMTISPDGKTLVILRVSRY 259
I+V+ + +E D V C T NIT W N++ +RM +S DGK L IL V R
Sbjct: 72 IAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQRE 131
Query: 260 DR-TIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNG-IVTAEIGSQVEMECI 317
D T QC + QRS+ I L V YGPD V ++ +G +V GS +
Sbjct: 132 DSGTYQCEARD-ALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAE 190
Query: 318 CYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENPVTQL 366
S Y W S+L+ + + +++ E G YRC V N T L
Sbjct: 191 TKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHL 239
>gi|156564393 carcinoembryonic antigen-related cell adhesion
molecule 20 5S [Homo sapiens]
Length = 584
Score = 79.7 bits (195), Expect = 4e-15
Identities = 64/222 (28%), Positives = 99/222 (44%), Gaps = 20/222 (9%)
Query: 166 TALNDTGNYTVRVVAGNETQRATGWLEVLELGSNLGISVNASSLVENMDSVAADCLT--N 223
T L+ G VRV LE L + + S+N LVEN SV C T
Sbjct: 237 THLSSLGTLKVRV------------LETLTMPQVVPSSLN---LVENARSVDLTCQTVNQ 281
Query: 224 VTNITWYVNDVPTSSSDRMTISPDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISL 282
N+ W+++ P S+ + +S D +TL+I + R D C + ++ RSE + L
Sbjct: 282 SVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSR-ARSEPLEL 340
Query: 283 TVAYGPDYV-LLRSNPDDFNGIVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFSDAK 341
T+ YGPD V + R + + + AE+ S + ++C S +Y W S +
Sbjct: 341 TINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQ 400
Query: 342 MNLSSLAWEQMGRYRCTVENPVTQLIMYMDVRIQAPHECSSS 383
+ + +L WE G Y CT N +T L V ++ SSS
Sbjct: 401 LIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQSSS 442
Score = 73.9 bits (180), Expect = 2e-13
Identities = 56/169 (33%), Positives = 78/169 (46%), Gaps = 5/169 (2%)
Query: 202 ISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSDRMTISPDGKTLVILRVSRY 259
I+V+ + +E D V C T NIT W N++ +RM +S DGK L IL V R
Sbjct: 72 IAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQRE 131
Query: 260 DR-TIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNG-IVTAEIGSQVEMECI 317
D T QC + QRS+ I L V YGPD V ++ +G +V GS +
Sbjct: 132 DSGTYQCEARD-ALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAE 190
Query: 318 CYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENPVTQL 366
S Y W S+L+ + + +++ E G YRC V N T L
Sbjct: 191 TKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHL 239
>gi|52317156 carcinoembryonic antigen-related cell adhesion molecule
isoform 2 [Homo sapiens]
Length = 292
Score = 74.3 bits (181), Expect = 2e-13
Identities = 62/222 (27%), Positives = 103/222 (46%), Gaps = 9/222 (4%)
Query: 72 WRRVFLMASLLACGICQASGQIFITQTLG--IKGYRTVVALDKVPEDVQEYSWYWGANDS 129
W+ + L ASLL + +FI +G +++ +PE++ Y WY G
Sbjct: 15 WQGLLLTASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPENLYSYGWYKGKTVE 74
Query: 130 AGNMIISHKPPS-AQQPGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVVAGN-ETQRA 187
+I ++ + + PGP Y+GRE ++ G L + L DTG Y ++V N + ++A
Sbjct: 75 PNQLIAAYVIDTHVRTPGPAYSGRETISPSGDLHFQNVTLEDTGYYNLQVTYRNSQIEQA 134
Query: 188 TGWLEVLELGSNLGISVNASSLVENMDSVAADCLTN--VTNITWYVNDVPTSSSDRMTIS 245
+ L V E + I +++++ E SV C TN T+ W N+ + RM +S
Sbjct: 135 SHHLRVYESVAQPSIQASSTTVTEK-GSVVLTCHTNNTGTSFQWIFNNQRLQVTKRMKLS 193
Query: 246 PDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISLTVAY 286
L I + + D QC + S P RS+ + LTV Y
Sbjct: 194 WFNHVLTIDPIRQEDAGEYQCEV-SNPVSSNRSDPLKLTVKY 234
>gi|148612793 carcinoembryonic antigen-related cell adhesion
molecule isoform 1 [Homo sapiens]
Length = 293
Score = 74.3 bits (181), Expect = 2e-13
Identities = 66/258 (25%), Positives = 116/258 (44%), Gaps = 18/258 (6%)
Query: 72 WRRVFLMASLLACGICQASGQIFITQTLG--IKGYRTVVALDKVPEDVQEYSWYWGANDS 129
W+ + L ASLL + +FI +G +++ +PE++ Y WY G
Sbjct: 15 WQGLLLTASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPENLYSYGWYKGKTVE 74
Query: 130 AGNMIISHKPPS-AQQPGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVVAGN-ETQRA 187
+I ++ + + PGP Y+GRE ++ G L + L DTG Y ++V N + ++A
Sbjct: 75 PNQLIAAYVIDTHVRTPGPAYSGRETISPSGDLHFQNVTLEDTGYYNLQVTYRNSQIEQA 134
Query: 188 TGWLEVLELGSNLGISVNASSLVENMDSVAADCLTN--VTNITWYVNDVPTSSSDRMTIS 245
+ L V E + I +++++ E SV C TN T+ W N+ + RM +S
Sbjct: 135 SHHLRVYESVAQPSIQASSTTVTEK-GSVVLTCHTNNTGTSFQWIFNNQRLQVTKRMKLS 193
Query: 246 PDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNGIV 304
L I + + D QC + S P RS+ + LTV +S+ + ++
Sbjct: 194 WFNHVLTIDPIRQEDAGEYQCEV-SNPVSSNRSDPLKLTV---------KSDDNTLGILI 243
Query: 305 TAEIGSQVEMECICYSFL 322
+GS + +C+ L
Sbjct: 244 GVLVGSLLVAALVCFLLL 261
>gi|156564390 carcinoembryonic antigen-related cell adhesion
molecule 20 4L [Homo sapiens]
Length = 503
Score = 73.9 bits (180), Expect = 2e-13
Identities = 56/169 (33%), Positives = 78/169 (46%), Gaps = 5/169 (2%)
Query: 202 ISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSDRMTISPDGKTLVILRVSRY 259
I+V+ + +E D V C T NIT W N++ +RM +S DGK L IL V R
Sbjct: 72 IAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQRE 131
Query: 260 DR-TIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNG-IVTAEIGSQVEMECI 317
D T QC + QRS+ I L V YGPD V ++ +G +V GS +
Sbjct: 132 DSGTYQCEARD-ALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAE 190
Query: 318 CYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENPVTQL 366
S Y W S+L+ + + +++ E G YRC V N T L
Sbjct: 191 TKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHL 239
Score = 38.1 bits (87), Expect = 0.014
Identities = 36/122 (29%), Positives = 55/122 (45%), Gaps = 19/122 (15%)
Query: 166 TALNDTGNYTVRVVAGNETQRATGWLEVLELGSNLGISVNASSLVENMDSVAADCLT--N 223
T L+ G VRV LE L + + S+N LVEN SV C T
Sbjct: 237 THLSSLGTLKVRV------------LETLTMPQVVPSSLN---LVENARSVDLTCQTVNQ 281
Query: 224 VTNITWYVNDVPTSSSDRMTISPDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISL 282
N+ W+++ P S+ + +S D +TL+I + R D C + ++ RSE + L
Sbjct: 282 SVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGS-RARSEPLEL 340
Query: 283 TV 284
T+
Sbjct: 341 TI 342
>gi|156564388 carcinoembryonic antigen-related cell adhesion
molecule 20 4S [Homo sapiens]
Length = 491
Score = 73.9 bits (180), Expect = 2e-13
Identities = 56/169 (33%), Positives = 78/169 (46%), Gaps = 5/169 (2%)
Query: 202 ISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSDRMTISPDGKTLVILRVSRY 259
I+V+ + +E D V C T NIT W N++ +RM +S DGK L IL V R
Sbjct: 72 IAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQRE 131
Query: 260 DR-TIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNG-IVTAEIGSQVEMECI 317
D T QC + QRS+ I L V YGPD V ++ +G +V GS +
Sbjct: 132 DSGTYQCEARD-ALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAE 190
Query: 318 CYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENPVTQL 366
S Y W S+L+ + + +++ E G YRC V N T L
Sbjct: 191 TKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHL 239
Score = 38.1 bits (87), Expect = 0.014
Identities = 36/122 (29%), Positives = 55/122 (45%), Gaps = 19/122 (15%)
Query: 166 TALNDTGNYTVRVVAGNETQRATGWLEVLELGSNLGISVNASSLVENMDSVAADCLT--N 223
T L+ G VRV LE L + + S+N LVEN SV C T
Sbjct: 237 THLSSLGTLKVRV------------LETLTMPQVVPSSLN---LVENARSVDLTCQTVNQ 281
Query: 224 VTNITWYVNDVPTSSSDRMTISPDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISL 282
N+ W+++ P S+ + +S D +TL+I + R D C + ++ RSE + L
Sbjct: 282 SVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGS-RARSEPLEL 340
Query: 283 TV 284
T+
Sbjct: 341 TI 342
>gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [Homo
sapiens]
Length = 435
Score = 68.9 bits (167), Expect = 7e-12
Identities = 80/327 (24%), Positives = 137/327 (41%), Gaps = 41/327 (12%)
Query: 72 WRRVFLMASLLACGICQASGQIFITQTLG--IKGYRTVVALDKVPEDVQEYSWYWGANDS 129
W+ + L ASLL + Q+ I +G ++ + +P+++ Y WY G
Sbjct: 15 WKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQMTD 74
Query: 130 AGNMIISHKPPSAQQPGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVV-AGNETQRAT 188
+ I S+ GP Y+GRE V SLLI+ D G+YT+ ++ G+ T T
Sbjct: 75 LYHYITSYVVHGQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSYTLHIIKRGDGTGGVT 134
Query: 189 GWLEVLELGSNLGISVNASSL--VENMDSVAADC--LTNVTNITWYVNDVPTSSSDRMTI 244
G+ V S+++S+L E M++V C T + W +N + R+ +
Sbjct: 135 GYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWLLNGQNLPMTHRLQL 194
Query: 245 SPDGKTLVILRVSRY-DRTIQCMIESFPEIFQRSERISLTVAYG---PDYVLLRSNPDDF 300
S +TL + V++Y +C I + P RS+ ++L + P + NP +
Sbjct: 195 SKTNRTLYLFGVTKYIAGPYECEIRN-PVSASRSDPVTLNLLPKLPMPYITINNLNPREK 253
Query: 301 NGIV--TAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFS--------DAKMNLSSLAWE 350
++ T E S+ + Y W NG L S + + L S+
Sbjct: 254 KDVLAFTCEPKSR-----------NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRN 302
Query: 351 QMGRYRCTV--------ENPVTQLIMY 369
+ G Y+C + NPVT ++Y
Sbjct: 303 ETGPYQCEIRDRYGGIRSNPVTLNVLY 329
Score = 48.9 bits (115), Expect = 8e-06
Identities = 43/167 (25%), Positives = 69/167 (41%), Gaps = 13/167 (7%)
Query: 202 ISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSDRMTISPDGKTLVILRVSRY 259
I++N + E D +A C N T W++N S R+ + + L++ V+R
Sbjct: 243 ITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRN 302
Query: 260 DR-TIQCMI-ESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNGIVTAEIGSQVEMECI 317
+ QC I + + I RS ++L V YGPD P + G +++ C
Sbjct: 303 ETGPYQCEIRDRYGGI--RSNPVTLNVLYGPDL------PRIYPSFTYYRSGENLDLSCF 354
Query: 318 CYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENPVT 364
S +Y W NG S K+ + + G Y C+V N T
Sbjct: 355 ADSNPPAEYSWTINGK-FQLSGQKLFIPQITTNHSGLYACSVRNSAT 400
>gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b
[Homo sapiens]
Length = 424
Score = 68.9 bits (167), Expect = 7e-12
Identities = 80/327 (24%), Positives = 137/327 (41%), Gaps = 41/327 (12%)
Query: 72 WRRVFLMASLLACGICQASGQIFITQTLG--IKGYRTVVALDKVPEDVQEYSWYWGANDS 129
W+ + L ASLL + Q+ I +G ++ + +P+++ Y WY G
Sbjct: 15 WKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQMTD 74
Query: 130 AGNMIISHKPPSAQQPGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVV-AGNETQRAT 188
+ I S+ GP Y+GRE V SLLI+ D G+YT+ ++ G+ T T
Sbjct: 75 LYHYITSYVVHGQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSYTLHIIKRGDGTGGVT 134
Query: 189 GWLEVLELGSNLGISVNASSL--VENMDSVAADC--LTNVTNITWYVNDVPTSSSDRMTI 244
G+ V S+++S+L E M++V C T + W +N + R+ +
Sbjct: 135 GYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWLLNGQNLPMTHRLQL 194
Query: 245 SPDGKTLVILRVSRY-DRTIQCMIESFPEIFQRSERISLTVAYG---PDYVLLRSNPDDF 300
S +TL + V++Y +C I + P RS+ ++L + P + NP +
Sbjct: 195 SKTNRTLYLFGVTKYIAGPYECEIRN-PVSASRSDPVTLNLLPKLPMPYITINNLNPREK 253
Query: 301 NGIV--TAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFS--------DAKMNLSSLAWE 350
++ T E S+ + Y W NG L S + + L S+
Sbjct: 254 KDVLAFTCEPKSR-----------NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRN 302
Query: 351 QMGRYRCTV--------ENPVTQLIMY 369
+ G Y+C + NPVT ++Y
Sbjct: 303 ETGPYQCEIRDRYGGIRSNPVTLNVLY 329
Score = 50.4 bits (119), Expect = 3e-06
Identities = 46/182 (25%), Positives = 76/182 (41%), Gaps = 15/182 (8%)
Query: 202 ISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSDRMTISPDGKTLVILRVSRY 259
I++N + E D +A C N T W++N S R+ + + L++ V+R
Sbjct: 243 ITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRN 302
Query: 260 DR-TIQCMI-ESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNGIVTAEIGSQVEMECI 317
+ QC I + + I RS ++L V YGPD P + G +++ C
Sbjct: 303 ETGPYQCEIRDRYGGI--RSNPVTLNVLYGPDL------PRIYPSFTYYRSGENLDLSCF 354
Query: 318 CYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENPVT--QLIMYMDVRIQ 375
S +Y W NG S K+ + + G Y C+V N T ++ M V++
Sbjct: 355 ADSNPPAEYSWTINGK-FQLSGQKLFIPQITTNHSGLYACSVRNSATGKEISKSMIVKVS 413
Query: 376 AP 377
P
Sbjct: 414 GP 415
>gi|194328710 pregnancy specific beta-1-glycoprotein 8 isoform b
[Homo sapiens]
Length = 419
Score = 65.9 bits (159), Expect = 6e-11
Identities = 82/330 (24%), Positives = 138/330 (41%), Gaps = 46/330 (13%)
Query: 72 WRRVFLMASLLACGICQASGQIFITQ--TLGIKGYRTVVALDKVPEDVQEYSWYWGANDS 129
W+ + L ASLL + Q+ I T +G ++ + +P+++ Y WY G
Sbjct: 15 WKGLLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74
Query: 130 AGNMIISHKPPSAQQP-GPMYTGRERVNREGSLLIRPTALNDTGNYTVRVV-AGNETQRA 187
+ I S+ GP Y+GRE + SLLI+ D G+YT+ ++ G+E +
Sbjct: 75 LYHYITSYVVDGQIIIYGPAYSGRETIYSNASLLIQNVTQEDAGSYTLHIIMGGDENRGV 134
Query: 188 TGWLEVLELGSNLGISVNASSL--VENMDSVAADC--LTNVTNITWYVNDVPTSSSDRMT 243
TG S+++S L E M++V+ C T + W++N S R+
Sbjct: 135 TGHFTFTLYLETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQ 194
Query: 244 ISPDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISLTV--AYGPDYVLL-----RS 295
+S +TL +L V++Y +C I + P RS+ +L + Y+ + R
Sbjct: 195 LSETNRTLFLLGVTKYTAGPYECEIRN-PVSASRSDPFTLNLLPKLPKPYITINNLKPRE 253
Query: 296 NPDDFNGIVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFS--------DAKMNLSSL 347
N D N T E S+ + Y W NG L S + + L S+
Sbjct: 254 NKDVLN--FTCEPKSE-----------NYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 300
Query: 348 AWEQMGRYRCTVEN--------PVTQLIMY 369
+ G Y+C + + PVT ++Y
Sbjct: 301 TRNETGPYQCEIRDQYGGIRSYPVTLNVLY 330
Score = 45.4 bits (106), Expect = 9e-05
Identities = 43/167 (25%), Positives = 68/167 (40%), Gaps = 13/167 (7%)
Query: 202 ISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSDRMTISPDGKTLVILRVSRY 259
I++N EN D + C N T W++N S R+ + + L++ V+R
Sbjct: 244 ITINNLKPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRN 303
Query: 260 DR-TIQCMI-ESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNGIVTAEIGSQVEMECI 317
+ QC I + + I RS ++L V YGPD P + G + + C
Sbjct: 304 ETGPYQCEIRDQYGGI--RSYPVTLNVLYGPDL------PRIYPSFTYYRSGEVLYLSCS 355
Query: 318 CYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENPVT 364
S +Y W NG S K+ + + + G Y C+V N T
Sbjct: 356 ADSNPPAQYSWTINGK-FQLSGQKLFIPQITTKHSGLYACSVRNSAT 401
>gi|51510887 pregnancy specific beta-1-glycoprotein 8 isoform a
[Homo sapiens]
Length = 426
Score = 65.9 bits (159), Expect = 6e-11
Identities = 82/330 (24%), Positives = 138/330 (41%), Gaps = 46/330 (13%)
Query: 72 WRRVFLMASLLACGICQASGQIFITQ--TLGIKGYRTVVALDKVPEDVQEYSWYWGANDS 129
W+ + L ASLL + Q+ I T +G ++ + +P+++ Y WY G
Sbjct: 15 WKGLLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74
Query: 130 AGNMIISHKPPSAQQP-GPMYTGRERVNREGSLLIRPTALNDTGNYTVRVV-AGNETQRA 187
+ I S+ GP Y+GRE + SLLI+ D G+YT+ ++ G+E +
Sbjct: 75 LYHYITSYVVDGQIIIYGPAYSGRETIYSNASLLIQNVTQEDAGSYTLHIIMGGDENRGV 134
Query: 188 TGWLEVLELGSNLGISVNASSL--VENMDSVAADC--LTNVTNITWYVNDVPTSSSDRMT 243
TG S+++S L E M++V+ C T + W++N S R+
Sbjct: 135 TGHFTFTLYLETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQ 194
Query: 244 ISPDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISLTV--AYGPDYVLL-----RS 295
+S +TL +L V++Y +C I + P RS+ +L + Y+ + R
Sbjct: 195 LSETNRTLFLLGVTKYTAGPYECEIRN-PVSASRSDPFTLNLLPKLPKPYITINNLKPRE 253
Query: 296 NPDDFNGIVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFS--------DAKMNLSSL 347
N D N T E S+ + Y W NG L S + + L S+
Sbjct: 254 NKDVLN--FTCEPKSE-----------NYTYIWWLNGQSLPVSPRVKRPIENRILILPSV 300
Query: 348 AWEQMGRYRCTVEN--------PVTQLIMY 369
+ G Y+C + + PVT ++Y
Sbjct: 301 TRNETGPYQCEIRDQYGGIRSYPVTLNVLY 330
Score = 45.4 bits (106), Expect = 9e-05
Identities = 43/167 (25%), Positives = 68/167 (40%), Gaps = 13/167 (7%)
Query: 202 ISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSDRMTISPDGKTLVILRVSRY 259
I++N EN D + C N T W++N S R+ + + L++ V+R
Sbjct: 244 ITINNLKPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRN 303
Query: 260 DR-TIQCMI-ESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNGIVTAEIGSQVEMECI 317
+ QC I + + I RS ++L V YGPD P + G + + C
Sbjct: 304 ETGPYQCEIRDQYGGI--RSYPVTLNVLYGPDL------PRIYPSFTYYRSGEVLYLSCS 355
Query: 318 CYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENPVT 364
S +Y W NG S K+ + + + G Y C+V N T
Sbjct: 356 ADSNPPAQYSWTINGK-FQLSGQKLFIPQITTKHSGLYACSVRNSAT 401
>gi|109240546 pregnancy specific beta-1-glycoprotein 3 [Homo
sapiens]
Length = 428
Score = 65.5 bits (158), Expect = 8e-11
Identities = 77/326 (23%), Positives = 140/326 (42%), Gaps = 38/326 (11%)
Query: 72 WRRVFLMASLLACGICQASGQIFITQ--TLGIKGYRTVVALDKVPEDVQEYSWYWGANDS 129
W+ + L A LL + Q+ I T KG ++ + +P+++ Y WY G
Sbjct: 15 WKGLLLTALLLNFWNLPTTAQVTIEAEPTKVSKGKDVLLLVHNLPQNLAGYIWYKGQMKD 74
Query: 130 AGNMIISHKPPSAQQP-GPMYTGRERVNREGSLLIRPTALNDTGNYTVRVV-AGNETQRA 187
+ I S+ GP Y+GRE V SLLI+ D G+YT+ +V G+ T+
Sbjct: 75 LYHYITSYVVDGQIIIYGPAYSGRETVYSNASLLIQNVTREDAGSYTLHIVKRGDGTRGE 134
Query: 188 TGWLEVLELGSNLGISVNASSLV--ENMDSVAADC--LTNVTNITWYVNDVPTSSSDRMT 243
TG S+++S+L E+M++V+ C T + W++N + +
Sbjct: 135 TGHFTFTLYLETPKPSISSSNLYPREDMEAVSLTCDPETPDASYLWWMNGQSLPMTHSLQ 194
Query: 244 ISPDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISLTV--AYGPDYVLLRS-NPDD 299
+S + +TL + V++Y +C I + P RS+ ++L + Y+ + + NP +
Sbjct: 195 LSKNKRTLFLFGVTKYTAGPYECEIRN-PVSASRSDPVTLNLLPKLPKPYITINNLNPRE 253
Query: 300 FNGIVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFS--------DAKMNLSSLAWEQ 351
++ + E + Y W NG L S + + L S+ +
Sbjct: 254 NKDVLAFTCEPKSE---------NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNE 304
Query: 352 MGRYRCTVEN--------PVTQLIMY 369
G Y+C +++ PVT ++Y
Sbjct: 305 TGPYQCEIQDRYGGIRSYPVTLNVLY 330
Score = 52.8 bits (125), Expect = 6e-07
Identities = 51/200 (25%), Positives = 83/200 (41%), Gaps = 20/200 (10%)
Query: 202 ISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSDRMTISPDGKTLVILRVSRY 259
I++N + EN D +A C N T W++N S R+ + + L++ V+R
Sbjct: 244 ITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRN 303
Query: 260 DR-TIQCMIES-FPEIFQRSERISLTVAYGPDYVLLRSNPDDFNGIVTAEIGSQVEMECI 317
+ QC I+ + I RS ++L V YGPD P + G + + C
Sbjct: 304 ETGPYQCEIQDRYGGI--RSYPVTLNVLYGPDL------PRIYPSFTYYHSGENLYLSCF 355
Query: 318 CYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENPVTQLIMYMDVRIQAP 377
S +Y W NG S K+ + + + G Y C+V N T + + ++
Sbjct: 356 ADSNPPAEYSWTINGK-FQLSGQKLFIPQITTKHSGLYACSVRNSATGMESSKSMTVKV- 413
Query: 378 HECSSSPPGSCFAHLPASMP 397
S+P G+ HLP P
Sbjct: 414 ----SAPSGT--GHLPGLNP 427
>gi|42560235 pregnancy specific beta-1-glycoprotein 4 isoform 1
[Homo sapiens]
Length = 419
Score = 64.7 bits (156), Expect = 1e-10
Identities = 78/326 (23%), Positives = 140/326 (42%), Gaps = 38/326 (11%)
Query: 72 WRRVFLMASLLACGICQASGQIFI-TQTLGI-KGYRTVVALDKVPEDVQEYSWYWGANDS 129
W+ V L ASLL + Q+ I Q + +G ++ + +P+++ Y WY G
Sbjct: 15 WKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLAGYIWYKGQMTY 74
Query: 130 AGNMIISHKPPSAQQP-GPMYTGRERVNREGSLLIRPTALNDTGNYTVRVVAGNE-TQRA 187
+ I S+ + GP Y+GRERV SLLI+ D G+YT+ ++ + T
Sbjct: 75 LYHYITSYVVDGQRIIYGPAYSGRERVYSNASLLIQNVTQEDAGSYTLHIIKRRDGTGGV 134
Query: 188 TGWLEVLELGSNLGISVNASSL--VENMDSVAADC--LTNVTNITWYVNDVPTSSSDRMT 243
TG S+++S+L E M++V C T + W++N + R+
Sbjct: 135 TGHFTFTLHLETPKPSISSSNLNPREAMEAVILTCDPATPAASYQWWMNGQSLPMTHRLQ 194
Query: 244 ISPDGKTLVILRVSRY-DRTIQCMIESFPEIFQRSERISLTV--AYGPDYVLLRS-NPDD 299
+S +TL I V++Y +C I + P RS+ ++L + Y+ + + NP +
Sbjct: 195 LSKTNRTLFIFGVTKYIAGPYECEIRN-PVSASRSDPVTLNLLPKLSKPYITINNLNPRE 253
Query: 300 FNGIVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFS--------DAKMNLSSLAWEQ 351
++T + + + Y W NG L S + + L ++ +
Sbjct: 254 NKDVLTFTCEPKSK---------NYTYIWWLNGQSLPVSPRVKRPIENRILILPNVTRNE 304
Query: 352 MGRYRCTV--------ENPVTQLIMY 369
G Y+C + +PVT ++Y
Sbjct: 305 TGPYQCEIRDRYGGIRSDPVTLNVLY 330
Score = 52.0 bits (123), Expect = 9e-07
Identities = 43/167 (25%), Positives = 71/167 (42%), Gaps = 13/167 (7%)
Query: 202 ISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSDRMTISPDGKTLVILRVSRY 259
I++N + EN D + C N T W++N S R+ + + L++ V+R
Sbjct: 244 ITINNLNPRENKDVLTFTCEPKSKNYTYIWWLNGQSLPVSPRVKRPIENRILILPNVTRN 303
Query: 260 DR-TIQCMI-ESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNGIVTAEIGSQVEMECI 317
+ QC I + + I RS+ ++L V YGPD P + G + + C
Sbjct: 304 ETGPYQCEIRDRYGGI--RSDPVTLNVLYGPDL------PSIYPSFTYYRSGENLYLSCF 355
Query: 318 CYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENPVT 364
S +Y W NG S K+++ + + G Y C+V N T
Sbjct: 356 AESNPRAQYSWTINGK-FQLSGQKLSIPQITTKHSGLYACSVRNSAT 401
>gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens]
Length = 426
Score = 64.3 bits (155), Expect = 2e-10
Identities = 76/326 (23%), Positives = 139/326 (42%), Gaps = 38/326 (11%)
Query: 72 WRRVFLMASLLACGICQASGQIFITQ--TLGIKGYRTVVALDKVPEDVQEYSWYWGANDS 129
W+ + L ASLL + Q+ I T +G ++ + +P+++ Y WY G
Sbjct: 15 WKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQMRD 74
Query: 130 AGNMIISHKPPSAQQP-GPMYTGRERVNREGSLLIRPTALNDTGNYTVRVVAGNE-TQRA 187
+ I S+ GP Y+GRE SLLI+ D G+YT+ ++ G++ T+
Sbjct: 75 LYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSYTLHIIKGDDGTRGV 134
Query: 188 TGWLEVLELGSNLGISVNASSL--VENMDSVAADC--LTNVTNITWYVNDVPTSSSDRMT 243
TG S+++S+L E M++V+ C T + W++N + +
Sbjct: 135 TGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLWWMNGQSLPMTHSLK 194
Query: 244 ISPDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISLTV--AYGPDYVLLRS-NPDD 299
+S +TL +L V++Y +C I + P RS+ ++L + Y+ + + NP +
Sbjct: 195 LSETNRTLFLLGVTKYTAGPYECEIRN-PVSASRSDPVTLNLLPKLPKPYITINNLNPRE 253
Query: 300 FNGIVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFS--------DAKMNLSSLAWEQ 351
++ + E + Y W NG L S + + L S+ +
Sbjct: 254 NKDVLNFTCEPKSE---------NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNE 304
Query: 352 MGRYRCTV--------ENPVTQLIMY 369
G Y+C + +PVT ++Y
Sbjct: 305 TGPYQCEIRDRYGGIRSDPVTLNVLY 330
Score = 40.8 bits (94), Expect = 0.002
Identities = 41/167 (24%), Positives = 68/167 (40%), Gaps = 13/167 (7%)
Query: 202 ISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSDRMTISPDGKTLVILRVSRY 259
I++N + EN D + C N T W++N S R+ + + L++ V+R
Sbjct: 244 ITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRN 303
Query: 260 DR-TIQCMI-ESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNGIVTAEIGSQVEMECI 317
+ QC I + + I RS+ ++L V YGPD P + G + + C
Sbjct: 304 ETGPYQCEIRDRYGGI--RSDPVTLNVLYGPDL------PRIYPSFTYYRSGEVLYLSCS 355
Query: 318 CYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENPVT 364
S +Y W N K+ + + + G Y C+V N T
Sbjct: 356 ADSNPPAQYSWTIN-EKFQLPGQKLFIRHITTKHSGLYVCSVRNSAT 401
>gi|157805480 pregnancy specific beta-1-glycoprotein 7 precursor
[Homo sapiens]
Length = 419
Score = 57.0 bits (136), Expect = 3e-08
Identities = 75/326 (23%), Positives = 136/326 (41%), Gaps = 38/326 (11%)
Query: 72 WRRVFLMASLLACGICQASGQIFI-TQTLGI-KGYRTVVALDKVPEDVQEYSWYWGANDS 129
W+ + L ASLL + Q+ I Q + +G ++ + +P+++ Y WY G
Sbjct: 15 WKGLLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74
Query: 130 AGNMIISH-KPPSAQQPGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVV-AGNETQRA 187
+ + S+ + GP Y+GRE V SLLI+ DTG+YT+ ++ G+ T
Sbjct: 75 LYHYVTSYIVDGQIIKYGPAYSGRETVYSNASLLIQNVTQEDTGSYTLHIIKRGDGTGGV 134
Query: 188 TGWLEVLELGSNLGISVNASSL--VENMDSVAADC--LTNVTNITWYVNDVPTSSSDRMT 243
TG S+++S+ E ++V C T + W++N + +
Sbjct: 135 TGRFTFTLYLETPKPSISSSNFNPREATEAVILTCDPETPDASYLWWMNGQSLPMTHSLQ 194
Query: 244 ISPDGKTLVILRVSRYDR-TIQCMIESFPEIFQRSERISLTV--AYGPDYVLLRS-NPDD 299
+S +TL + V+ Y +C I + P RS+ ++L + Y+ + + NP +
Sbjct: 195 LSETNRTLYLFGVTNYTAGPYECEIRN-PVSASRSDPVTLNLLPKLPKPYITINNLNPRE 253
Query: 300 FNGIVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFS--------DAKMNLSSLAWEQ 351
+ T + E + Y W NG L S + + L S+ +
Sbjct: 254 NKDVSTFTCEPKSE---------NYTYIWWLNGQSLPVSPRVKRRIENRILILPSVTRNE 304
Query: 352 MGRYRCTV--------ENPVTQLIMY 369
G Y+C + +PVT ++Y
Sbjct: 305 TGPYQCEIRDRYGGIRSDPVTLNVLY 330
Score = 49.7 bits (117), Expect = 5e-06
Identities = 43/167 (25%), Positives = 70/167 (41%), Gaps = 13/167 (7%)
Query: 202 ISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSDRMTISPDGKTLVILRVSRY 259
I++N + EN D C N T W++N S R+ + + L++ V+R
Sbjct: 244 ITINNLNPRENKDVSTFTCEPKSENYTYIWWLNGQSLPVSPRVKRRIENRILILPSVTRN 303
Query: 260 DR-TIQCMI-ESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNGIVTAEIGSQVEMECI 317
+ QC I + + I RS+ ++L V YGPD P + G + + C
Sbjct: 304 ETGPYQCEIRDRYGGI--RSDPVTLNVLYGPDL------PRIYPSFTYYHSGQNLYLSCF 355
Query: 318 CYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENPVT 364
S +Y W NG S K+++ + + G Y C+V N T
Sbjct: 356 ADSNPPAQYSWTINGK-FQLSGQKLSIPQITTKHSGLYACSVRNSAT 401
>gi|156616284 pregnancy specific beta-1-glycoprotein 9 [Homo
sapiens]
Length = 426
Score = 55.1 bits (131), Expect = 1e-07
Identities = 75/326 (23%), Positives = 134/326 (41%), Gaps = 38/326 (11%)
Query: 72 WRRVFLMASLLACGICQASGQIFI-TQTLGI-KGYRTVVALDKVPEDVQEYSWYWGANDS 129
W+ + L ASLL + ++ I Q + +G ++ + +P+++ Y WY G
Sbjct: 15 WKGLLLTASLLNFWNPPTTAEVTIEAQPPKVSEGKDVLLLVHNLPQNLPGYFWYKGEMTD 74
Query: 130 AGNMIISH-KPPSAQQPGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVV-AGNETQRA 187
+ IIS+ GP Y+GRE V SLLI+ D G YT+ ++ G+ET+
Sbjct: 75 LYHYIISYIVDGKIIIYGPAYSGRETVYSNASLLIQNVTRKDAGTYTLHIIKRGDETREE 134
Query: 188 TGWLEVLELGSNLGISVNASSL--VENMDSVAADC--LTNVTNITWYVNDVPTSSSDRMT 243
+++S+L E M++V C T + W++N + R+
Sbjct: 135 IRHFTFTLYLETPKPYISSSNLNPREAMEAVRLICDPETLDASYLWWMNGQSLPVTHRLQ 194
Query: 244 ISPDGKTLVILRVSRY-DRTIQCMIESFPEIFQRSERISLTVAYG---PDYVLLRSNPDD 299
+S +TL + V++Y +C I + P RS+ ++L + P + NP +
Sbjct: 195 LSKTNRTLYLFGVTKYIAGPYECEIRN-PVSASRSDPVTLNLLPKLPIPYITINNLNPRE 253
Query: 300 FNGIVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFS--------DAKMNLSSLAWEQ 351
++ + E + Y W NG L S + + L S+ +
Sbjct: 254 NKDVLAFTCEPKSE---------NYTYIWWLNGQSLPVSPGVKRPIENRILILPSVTRNE 304
Query: 352 MGRYRCTV--------ENPVTQLIMY 369
G Y+C + NPV ++Y
Sbjct: 305 TGPYQCEIRDRYGGLRSNPVILNVLY 330
Score = 47.8 bits (112), Expect = 2e-05
Identities = 45/182 (24%), Positives = 75/182 (41%), Gaps = 15/182 (8%)
Query: 202 ISVNASSLVENMDSVAADCLTNVTNIT--WYVNDVPTSSSDRMTISPDGKTLVILRVSRY 259
I++N + EN D +A C N T W++N S + + + L++ V+R
Sbjct: 244 ITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPGVKRPIENRILILPSVTRN 303
Query: 260 DR-TIQCMI-ESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNGIVTAEIGSQVEMECI 317
+ QC I + + + RS + L V YGPD P + G +++ C
Sbjct: 304 ETGPYQCEIRDRYGGL--RSNPVILNVLYGPDL------PRIYPSFTYYRSGENLDLSCF 355
Query: 318 CYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENPVT--QLIMYMDVRIQ 375
S +Y W NG S K+ + + G Y C+V N T ++ M V++
Sbjct: 356 TESNPPAEYFWTINGKFQQ-SGQKLFIPQITRNHSGLYACSVHNSATGKEISKSMTVKVS 414
Query: 376 AP 377
P
Sbjct: 415 GP 416
>gi|121114300 carcinoembryonic antigen-related cell adhesion
molecule 3 precursor [Homo sapiens]
Length = 252
Score = 54.7 bits (130), Expect = 1e-07
Identities = 37/128 (28%), Positives = 65/128 (50%), Gaps = 4/128 (3%)
Query: 72 WRRVFLMASLLACGICQASGQIFI-TQTLGI-KGYRTVVALDKVPEDVQEYSWYWGANDS 129
W+ + L ASLL + ++ I + L + +G ++ + +P+ + YSWY G
Sbjct: 15 WQGLLLTASLLNFWNPPTTAKLTIESMPLSVAEGKEVLLLVHNLPQHLFGYSWYKGERVD 74
Query: 130 AGNMIISHKPPSAQQ-PGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVVAGN-ETQRA 187
++I+ + + Q PG Y+GRE + SLLI+ ND G YT++V+ + + A
Sbjct: 75 GNSLIVGYVIGTQQATPGAAYSGRETIYTNASLLIQNVTQNDIGFYTLQVIKSDLVNEEA 134
Query: 188 TGWLEVLE 195
TG V +
Sbjct: 135 TGQFHVYQ 142
>gi|71143132 carcinoembryonic antigen-related cell adhesion molecule
4 [Homo sapiens]
Length = 244
Score = 53.9 bits (128), Expect = 2e-07
Identities = 38/126 (30%), Positives = 59/126 (46%), Gaps = 4/126 (3%)
Query: 72 WRRVFLMASLLACGICQASGQIFITQ--TLGIKGYRTVVALDKVPEDVQEYSWYWGANDS 129
W+ + + ASLL + Q I + +G ++ + E +Q Y W+ G
Sbjct: 15 WQGLLITASLLTFWHPPTTVQFTIEALPSSAAEGKDVLLLACNISETIQAYYWHKGKTAE 74
Query: 130 AGNMIISHKPP-SAQQPGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVV-AGNETQRA 187
+I + A PG Y+GRE V GSLL + L D G+YT+R + A ++ +A
Sbjct: 75 GSPLIAGYITDIQANIPGAAYSGRETVYPNGSLLFQNITLEDAGSYTLRTINASYDSDQA 134
Query: 188 TGWLEV 193
TG L V
Sbjct: 135 TGQLHV 140
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,773,555
Number of Sequences: 37866
Number of extensions: 680951
Number of successful extensions: 2614
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 81
Number of HSP's that attempted gapping in prelim test: 2181
Number of HSP's gapped (non-prelim): 437
length of query: 398
length of database: 18,247,518
effective HSP length: 104
effective length of query: 294
effective length of database: 14,309,454
effective search space: 4206979476
effective search space used: 4206979476
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.