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Search of human proteins with 12025671
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|12025671 chloride channel 6 isoform ClC-6c [Homo sapiens]
(353 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|12025671 chloride channel 6 isoform ClC-6c [Homo sapiens] 726 0.0
gi|4502873 chloride channel 6 isoform ClC-6a [Homo sapiens] 652 0.0
gi|12025673 chloride channel 6 isoform ClC-6d [Homo sapiens] 485 e-137
gi|12025668 chloride channel 6 isoform ClC-6b [Homo sapiens] 485 e-137
gi|167466160 chloride channel 7 isoform b [Homo sapiens] 288 5e-78
gi|14149607 chloride channel 7 isoform a [Homo sapiens] 288 5e-78
gi|55770840 chloride channel 3 isoform e [Homo sapiens] 114 1e-25
gi|55770838 chloride channel 3 isoform b [Homo sapiens] 114 1e-25
gi|153252026 chloride channel 4 [Homo sapiens] 114 1e-25
gi|189217923 chloride channel 5 isoform a [Homo sapiens] 108 7e-24
gi|189217921 chloride channel 5 isoform a [Homo sapiens] 108 7e-24
gi|4557473 chloride channel 5 isoform b [Homo sapiens] 108 7e-24
gi|119433677 chloride channel 1, skeletal muscle [Homo sapiens] 103 3e-22
gi|156104869 chloride channel 2 [Homo sapiens] 98 1e-20
gi|155969705 chloride channel Kb [Homo sapiens] 73 3e-13
gi|112382220 chloride channel Ka isoform 1 [Homo sapiens] 73 4e-13
gi|112382222 chloride channel Ka isoform 2 [Homo sapiens] 73 4e-13
gi|13654235 regulator of G-protein signaling 20 isoform b [Homo ... 36 0.060
gi|41281805 regulator of G-protein signaling 20 isoform a [Homo ... 36 0.060
gi|169204828 PREDICTED: hypothetical protein [Homo sapiens] 35 0.13
gi|169205567 PREDICTED: hypothetical protein [Homo sapiens] 35 0.13
gi|169204182 PREDICTED: hypothetical protein [Homo sapiens] 35 0.13
gi|45504382 DnaJ (Hsp40) homolog, subfamily C, member 5 [Homo sa... 31 1.5
gi|29126218 DnaJ (Hsp40) homolog, subfamily C, member 5 beta [Ho... 31 1.5
gi|37700254 triggering receptor expressed on myeloid cells-like ... 30 4.3
gi|239755634 PREDICTED: hypothetical protein [Homo sapiens] 29 5.6
gi|239750121 PREDICTED: hypothetical protein XP_002347280 [Homo ... 29 5.6
gi|239744429 PREDICTED: hypothetical protein XP_002343157 [Homo ... 29 5.6
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] 28 9.5
gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens] 28 9.5
>gi|12025671 chloride channel 6 isoform ClC-6c [Homo sapiens]
Length = 353
Score = 726 bits (1875), Expect = 0.0
Identities = 353/353 (100%), Positives = 353/353 (100%)
Query: 1 MAGCRGSLCCCCRWCCCCGERETRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDP 60
MAGCRGSLCCCCRWCCCCGERETRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDP
Sbjct: 1 MAGCRGSLCCCCRWCCCCGERETRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDP 60
Query: 61 YLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFFVRLFTQLKFGVVQTSVEEC 120
YLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFFVRLFTQLKFGVVQTSVEEC
Sbjct: 61 YLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFFVRLFTQLKFGVVQTSVEEC 120
Query: 121 SQKGCLALSLLELLGFNLTFVFLASLLVLIEPVAAGSGIPEVKCYLNGVKVPGIVRLRTL 180
SQKGCLALSLLELLGFNLTFVFLASLLVLIEPVAAGSGIPEVKCYLNGVKVPGIVRLRTL
Sbjct: 121 SQKGCLALSLLELLGFNLTFVFLASLLVLIEPVAAGSGIPEVKCYLNGVKVPGIVRLRTL 180
Query: 181 LCKVLGVLFSVAGGLFVGKEGPMIHSGSVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRD 240
LCKVLGVLFSVAGGLFVGKEGPMIHSGSVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRD
Sbjct: 181 LCKVLGVLFSVAGGLFVGKEGPMIHSGSVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRD 240
Query: 241 FVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWKVLFCSMSATFTLNFFRSGIQF 300
FVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWKVLFCSMSATFTLNFFRSGIQF
Sbjct: 241 FVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWKVLFCSMSATFTLNFFRSGIQF 300
Query: 301 GSWGSFQLPGLLNFGEFKSLREPPCVSGNHRGGVCGLDGVRRMPTDVLFESNR 353
GSWGSFQLPGLLNFGEFKSLREPPCVSGNHRGGVCGLDGVRRMPTDVLFESNR
Sbjct: 301 GSWGSFQLPGLLNFGEFKSLREPPCVSGNHRGGVCGLDGVRRMPTDVLFESNR 353
>gi|4502873 chloride channel 6 isoform ClC-6a [Homo sapiens]
Length = 869
Score = 652 bits (1683), Expect = 0.0
Identities = 318/318 (100%), Positives = 318/318 (100%)
Query: 1 MAGCRGSLCCCCRWCCCCGERETRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDP 60
MAGCRGSLCCCCRWCCCCGERETRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDP
Sbjct: 1 MAGCRGSLCCCCRWCCCCGERETRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDP 60
Query: 61 YLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFFVRLFTQLKFGVVQTSVEEC 120
YLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFFVRLFTQLKFGVVQTSVEEC
Sbjct: 61 YLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFFVRLFTQLKFGVVQTSVEEC 120
Query: 121 SQKGCLALSLLELLGFNLTFVFLASLLVLIEPVAAGSGIPEVKCYLNGVKVPGIVRLRTL 180
SQKGCLALSLLELLGFNLTFVFLASLLVLIEPVAAGSGIPEVKCYLNGVKVPGIVRLRTL
Sbjct: 121 SQKGCLALSLLELLGFNLTFVFLASLLVLIEPVAAGSGIPEVKCYLNGVKVPGIVRLRTL 180
Query: 181 LCKVLGVLFSVAGGLFVGKEGPMIHSGSVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRD 240
LCKVLGVLFSVAGGLFVGKEGPMIHSGSVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRD
Sbjct: 181 LCKVLGVLFSVAGGLFVGKEGPMIHSGSVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRD 240
Query: 241 FVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWKVLFCSMSATFTLNFFRSGIQF 300
FVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWKVLFCSMSATFTLNFFRSGIQF
Sbjct: 241 FVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWKVLFCSMSATFTLNFFRSGIQF 300
Query: 301 GSWGSFQLPGLLNFGEFK 318
GSWGSFQLPGLLNFGEFK
Sbjct: 301 GSWGSFQLPGLLNFGEFK 318
>gi|12025673 chloride channel 6 isoform ClC-6d [Homo sapiens]
Length = 308
Score = 485 bits (1249), Expect = e-137
Identities = 236/236 (100%), Positives = 236/236 (100%)
Query: 1 MAGCRGSLCCCCRWCCCCGERETRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDP 60
MAGCRGSLCCCCRWCCCCGERETRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDP
Sbjct: 1 MAGCRGSLCCCCRWCCCCGERETRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDP 60
Query: 61 YLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFFVRLFTQLKFGVVQTSVEEC 120
YLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFFVRLFTQLKFGVVQTSVEEC
Sbjct: 61 YLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFFVRLFTQLKFGVVQTSVEEC 120
Query: 121 SQKGCLALSLLELLGFNLTFVFLASLLVLIEPVAAGSGIPEVKCYLNGVKVPGIVRLRTL 180
SQKGCLALSLLELLGFNLTFVFLASLLVLIEPVAAGSGIPEVKCYLNGVKVPGIVRLRTL
Sbjct: 121 SQKGCLALSLLELLGFNLTFVFLASLLVLIEPVAAGSGIPEVKCYLNGVKVPGIVRLRTL 180
Query: 181 LCKVLGVLFSVAGGLFVGKEGPMIHSGSVVGAGLPQFQSISLRKIQFNFPYFRSDR 236
LCKVLGVLFSVAGGLFVGKEGPMIHSGSVVGAGLPQFQSISLRKIQFNFPYFRSDR
Sbjct: 181 LCKVLGVLFSVAGGLFVGKEGPMIHSGSVVGAGLPQFQSISLRKIQFNFPYFRSDR 236
>gi|12025668 chloride channel 6 isoform ClC-6b [Homo sapiens]
Length = 320
Score = 485 bits (1249), Expect = e-137
Identities = 236/236 (100%), Positives = 236/236 (100%)
Query: 1 MAGCRGSLCCCCRWCCCCGERETRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDP 60
MAGCRGSLCCCCRWCCCCGERETRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDP
Sbjct: 1 MAGCRGSLCCCCRWCCCCGERETRTPEELTILGETQEEEDEILPRKDYESLDYDRCINDP 60
Query: 61 YLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFFVRLFTQLKFGVVQTSVEEC 120
YLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFFVRLFTQLKFGVVQTSVEEC
Sbjct: 61 YLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFFVRLFTQLKFGVVQTSVEEC 120
Query: 121 SQKGCLALSLLELLGFNLTFVFLASLLVLIEPVAAGSGIPEVKCYLNGVKVPGIVRLRTL 180
SQKGCLALSLLELLGFNLTFVFLASLLVLIEPVAAGSGIPEVKCYLNGVKVPGIVRLRTL
Sbjct: 121 SQKGCLALSLLELLGFNLTFVFLASLLVLIEPVAAGSGIPEVKCYLNGVKVPGIVRLRTL 180
Query: 181 LCKVLGVLFSVAGGLFVGKEGPMIHSGSVVGAGLPQFQSISLRKIQFNFPYFRSDR 236
LCKVLGVLFSVAGGLFVGKEGPMIHSGSVVGAGLPQFQSISLRKIQFNFPYFRSDR
Sbjct: 181 LCKVLGVLFSVAGGLFVGKEGPMIHSGSVVGAGLPQFQSISLRKIQFNFPYFRSDR 236
>gi|167466160 chloride channel 7 isoform b [Homo sapiens]
Length = 781
Score = 288 bits (737), Expect = 5e-78
Identities = 149/273 (54%), Positives = 193/273 (70%), Gaps = 2/273 (0%)
Query: 48 YESLDYDRCINDPYLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFFVRLFTQ 107
YESLDYD N +LE +++ R E +W++ IG+ TGLV F+D V
Sbjct: 70 YESLDYDNSENQLFLEEERRINHTAFRTVEIKRWVICALIGILTGLVACFIDIVVENLAG 129
Query: 108 LKFGVVQTSVEECSQKGCLALSLLELLGFNLTFVFLASLLV-LIEPVAAGSGIPEVKCYL 166
LK+ V++ ++++ ++KG L+ SLL N FV + S++V IEPVAAGSGIP++KC+L
Sbjct: 130 LKYRVIKGNIDKFTEKGGLSFSLLLWATLNAAFVLVGSVIVAFIEPVAAGSGIPQIKCFL 189
Query: 167 NGVKVPGIVRLRTLLCKVLGVLFSVAGGLFVGKEGPMIHSGSVVGAGLPQFQSISLRKIQ 226
NGVK+P +VRL+TL+ KV GV+ SV GGL VGKEGPMIHSGSV+ AG+ Q +S SL++
Sbjct: 190 NGVKIPHVVRLKTLVIKVSGVILSVVGGLAVGKEGPMIHSGSVIAAGISQGRSTSLKRDF 249
Query: 227 FNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWKVLFCSMS 286
F YFR D +KRDFVSAGAAAGV+AAFGAP+GG LFSLEEG+SFWNQ LTW++ F SM
Sbjct: 250 KIFEYFRRDTEKRDFVSAGAAAGVSAAFGAPVGGVLFSLEEGASFWNQFLTWRIFFASMI 309
Query: 287 ATFTLNFFRSGIQFGSWGSFQLPGLLNFGEFKS 319
+TFTLNF S I G+ PGL+NFG F S
Sbjct: 310 STFTLNFVLS-IYHGNMWDLSSPGLINFGRFDS 341
>gi|14149607 chloride channel 7 isoform a [Homo sapiens]
Length = 805
Score = 288 bits (737), Expect = 5e-78
Identities = 149/273 (54%), Positives = 193/273 (70%), Gaps = 2/273 (0%)
Query: 48 YESLDYDRCINDPYLEVLETMDNKKGRRYEAVKWMVVFAIGVCTGLVGLFVDFFVRLFTQ 107
YESLDYD N +LE +++ R E +W++ IG+ TGLV F+D V
Sbjct: 94 YESLDYDNSENQLFLEEERRINHTAFRTVEIKRWVICALIGILTGLVACFIDIVVENLAG 153
Query: 108 LKFGVVQTSVEECSQKGCLALSLLELLGFNLTFVFLASLLV-LIEPVAAGSGIPEVKCYL 166
LK+ V++ ++++ ++KG L+ SLL N FV + S++V IEPVAAGSGIP++KC+L
Sbjct: 154 LKYRVIKGNIDKFTEKGGLSFSLLLWATLNAAFVLVGSVIVAFIEPVAAGSGIPQIKCFL 213
Query: 167 NGVKVPGIVRLRTLLCKVLGVLFSVAGGLFVGKEGPMIHSGSVVGAGLPQFQSISLRKIQ 226
NGVK+P +VRL+TL+ KV GV+ SV GGL VGKEGPMIHSGSV+ AG+ Q +S SL++
Sbjct: 214 NGVKIPHVVRLKTLVIKVSGVILSVVGGLAVGKEGPMIHSGSVIAAGISQGRSTSLKRDF 273
Query: 227 FNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWKVLFCSMS 286
F YFR D +KRDFVSAGAAAGV+AAFGAP+GG LFSLEEG+SFWNQ LTW++ F SM
Sbjct: 274 KIFEYFRRDTEKRDFVSAGAAAGVSAAFGAPVGGVLFSLEEGASFWNQFLTWRIFFASMI 333
Query: 287 ATFTLNFFRSGIQFGSWGSFQLPGLLNFGEFKS 319
+TFTLNF S I G+ PGL+NFG F S
Sbjct: 334 STFTLNFVLS-IYHGNMWDLSSPGLINFGRFDS 365
>gi|55770840 chloride channel 3 isoform e [Homo sapiens]
Length = 866
Score = 114 bits (286), Expect = 1e-25
Identities = 80/246 (32%), Positives = 120/246 (48%), Gaps = 46/246 (18%)
Query: 81 WMVVFAIGVCTGLVGLFVDFFVRLFTQLKFGVV----------------QTSVEE---CS 121
W+VV G+ +G + +D T LK G+ +T+ EE C
Sbjct: 129 WLVVTLTGLASGALAGLIDIAADWMTDLKEGICLSALWYNHEQCCWGSNETTFEERDKCP 188
Query: 122 Q--------------KGCLALSLLELLGFNLTFVFLA-SLLVLIEPVAAGSGIPEVKCYL 166
Q G ++ + + + L+F FLA SL+ + P A GSGIPE+K L
Sbjct: 189 QWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGSGIPEIKTIL 248
Query: 167 NGVKVPGIVRLRTLLCKVLGVLFSVAGGLFVGKEGPMIHSGSVVGAGLPQFQSISLRKIQ 226
+G + G + TL+ K + ++ +VA GL +GKEGP++H G
Sbjct: 249 SGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVACCCG-----------NIFS 297
Query: 227 FNFP-YFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWKVLFCSM 285
+ FP Y ++ KR+ +SA +AAGV+ AFGAPIGG LFSLEE S ++ W+ F ++
Sbjct: 298 YLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAAL 357
Query: 286 SATFTL 291
A F L
Sbjct: 358 VAAFVL 363
>gi|55770838 chloride channel 3 isoform b [Homo sapiens]
Length = 818
Score = 114 bits (286), Expect = 1e-25
Identities = 80/246 (32%), Positives = 120/246 (48%), Gaps = 46/246 (18%)
Query: 81 WMVVFAIGVCTGLVGLFVDFFVRLFTQLKFGVV----------------QTSVEE---CS 121
W+VV G+ +G + +D T LK G+ +T+ EE C
Sbjct: 129 WLVVTLTGLASGALAGLIDIAADWMTDLKEGICLSALWYNHEQCCWGSNETTFEERDKCP 188
Query: 122 Q--------------KGCLALSLLELLGFNLTFVFLA-SLLVLIEPVAAGSGIPEVKCYL 166
Q G ++ + + + L+F FLA SL+ + P A GSGIPE+K L
Sbjct: 189 QWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGSGIPEIKTIL 248
Query: 167 NGVKVPGIVRLRTLLCKVLGVLFSVAGGLFVGKEGPMIHSGSVVGAGLPQFQSISLRKIQ 226
+G + G + TL+ K + ++ +VA GL +GKEGP++H G
Sbjct: 249 SGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVACCCG-----------NIFS 297
Query: 227 FNFP-YFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWKVLFCSM 285
+ FP Y ++ KR+ +SA +AAGV+ AFGAPIGG LFSLEE S ++ W+ F ++
Sbjct: 298 YLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAAL 357
Query: 286 SATFTL 291
A F L
Sbjct: 358 VAAFVL 363
>gi|153252026 chloride channel 4 [Homo sapiens]
Length = 760
Score = 114 bits (285), Expect = 1e-25
Identities = 85/245 (34%), Positives = 121/245 (49%), Gaps = 44/245 (17%)
Query: 81 WMVVFAIGVCTGLVGLFVDFFVRLFTQLKFGVVQT----SVEEC---------------- 120
W+V+ IG+ G + +D V T LK GV + S E+C
Sbjct: 71 WVVMLLIGLLAGTLAGVIDLAVDWMTDLKEGVCLSAFWYSHEQCCWTSNETTFEDRDKCP 130
Query: 121 -----------SQKGCLA--LSLLELLGFNLTFVFLA-SLLVLIEPVAAGSGIPEVKCYL 166
+G A L+ L + + L F FLA SL+ + P A GSGIPE+K L
Sbjct: 131 LWQKWSELLVNQSEGASAYILNYLMYILWALLFAFLAVSLVRVFAPYACGSGIPEIKTIL 190
Query: 167 NGVKVPGIVRLRTLLCKVLGVLFSVAGGLFVGKEGPMIHSGSVVGAGLPQFQSISLRKIQ 226
+G + G + TLL K + ++ V+ GL +GKEGP++H G F S K
Sbjct: 191 SGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVACCCG----NFFSSLFSK-- 244
Query: 227 FNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEEGSSFWNQGLTWKVLFCSMS 286
Y +++ +R+ +SA AAAGV+ AFGAPIGG LFSLEE S ++ W+ F ++
Sbjct: 245 ----YSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALV 300
Query: 287 ATFTL 291
A FTL
Sbjct: 301 AAFTL 305
>gi|189217923 chloride channel 5 isoform a [Homo sapiens]
Length = 816
Score = 108 bits (270), Expect = 7e-24
Identities = 75/197 (38%), Positives = 105/197 (53%), Gaps = 27/197 (13%)
Query: 138 LTFVFLA-SLLVLIEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGGLF 196
L F FLA SL+ + P A GSGIPE+K L+G + G + TL+ K + ++ +V+ GL
Sbjct: 218 LLFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLS 277
Query: 197 VGKEGPMIHSGSVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGA 256
+GKEGP++H G L FN Y +++ +R+ +SA AAAGV+ AFGA
Sbjct: 278 LGKEGPLVHVACCCGNILCHC---------FN-KYRKNEAKRREVLSAAAAAGVSVAFGA 327
Query: 257 PIGGTLFSLEEGSSFWNQGLTWKVLFCSMSATFTLNFFRSGIQFGS-------------W 303
PIGG LFSLEE S ++ W+ F ++ A FTL RS FG+ W
Sbjct: 328 PIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTL---RSINPFGNSRLVLFYVEFHTPW 384
Query: 304 GSFQLPGLLNFGEFKSL 320
F+L + G F L
Sbjct: 385 HLFELVPFILLGIFGGL 401
>gi|189217921 chloride channel 5 isoform a [Homo sapiens]
Length = 816
Score = 108 bits (270), Expect = 7e-24
Identities = 75/197 (38%), Positives = 105/197 (53%), Gaps = 27/197 (13%)
Query: 138 LTFVFLA-SLLVLIEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGGLF 196
L F FLA SL+ + P A GSGIPE+K L+G + G + TL+ K + ++ +V+ GL
Sbjct: 218 LLFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLS 277
Query: 197 VGKEGPMIHSGSVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGA 256
+GKEGP++H G L FN Y +++ +R+ +SA AAAGV+ AFGA
Sbjct: 278 LGKEGPLVHVACCCGNILCHC---------FN-KYRKNEAKRREVLSAAAAAGVSVAFGA 327
Query: 257 PIGGTLFSLEEGSSFWNQGLTWKVLFCSMSATFTLNFFRSGIQFGS-------------W 303
PIGG LFSLEE S ++ W+ F ++ A FTL RS FG+ W
Sbjct: 328 PIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTL---RSINPFGNSRLVLFYVEFHTPW 384
Query: 304 GSFQLPGLLNFGEFKSL 320
F+L + G F L
Sbjct: 385 HLFELVPFILLGIFGGL 401
>gi|4557473 chloride channel 5 isoform b [Homo sapiens]
Length = 746
Score = 108 bits (270), Expect = 7e-24
Identities = 75/197 (38%), Positives = 105/197 (53%), Gaps = 27/197 (13%)
Query: 138 LTFVFLA-SLLVLIEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGGLF 196
L F FLA SL+ + P A GSGIPE+K L+G + G + TL+ K + ++ +V+ GL
Sbjct: 148 LLFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLS 207
Query: 197 VGKEGPMIHSGSVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGA 256
+GKEGP++H G L FN Y +++ +R+ +SA AAAGV+ AFGA
Sbjct: 208 LGKEGPLVHVACCCGNILCHC---------FN-KYRKNEAKRREVLSAAAAAGVSVAFGA 257
Query: 257 PIGGTLFSLEEGSSFWNQGLTWKVLFCSMSATFTLNFFRSGIQFGS-------------W 303
PIGG LFSLEE S ++ W+ F ++ A FTL RS FG+ W
Sbjct: 258 PIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTL---RSINPFGNSRLVLFYVEFHTPW 314
Query: 304 GSFQLPGLLNFGEFKSL 320
F+L + G F L
Sbjct: 315 HLFELVPFILLGIFGGL 331
>gi|119433677 chloride channel 1, skeletal muscle [Homo sapiens]
Length = 988
Score = 103 bits (256), Expect = 3e-22
Identities = 77/265 (29%), Positives = 124/265 (46%), Gaps = 21/265 (7%)
Query: 35 TQEEEDEILPRKDYESLDYDRCINDPYLEVLETMDN--KKGRRYEAVKWMVVFAIGVCTG 92
+ E+D +P+K S D D Y + + + + RR W+ + +G+
Sbjct: 70 SDREQDIGMPKKTGSSSTVDSKDEDHYSKCQDCIHRLGQVVRRKLGEDWIFLVLLGLLMA 129
Query: 93 LVGLFVDFF-VRLFTQLKFGVVQTSVEECSQKGCLALSLLELLGFNLTFVFLASLLV-LI 150
LV +D+ + K+ Q + L L L + F L + ++L LI
Sbjct: 130 LVSWSMDYVSAKSLQAYKWSYAQ-------MQPSLPLQFLVWVTFPLVLILFSALFCHLI 182
Query: 151 EPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGGLFVGKEGPMIHSGSVV 210
P A GSGIPE+K L GV + + ++ + KV+ + + G+ VGKEGP +H S+
Sbjct: 183 SPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIASIC 242
Query: 211 GAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEEGSS 270
A L +F S+ + PY+ S D ++ G A GV FG P+GG LFS+E S+
Sbjct: 243 AAVLSKFMSVFCG--VYEQPYYYS-----DILTVGCAVGVGCCFGTPLGGVLFSIEVTST 295
Query: 271 FWNQGLTWKVLFCSMSATFTLNFFR 295
++ W+ F +ATF+ FR
Sbjct: 296 YFAVRNYWRGFF---AATFSAFVFR 317
>gi|156104869 chloride channel 2 [Homo sapiens]
Length = 898
Score = 97.8 bits (242), Expect = 1e-20
Identities = 67/219 (30%), Positives = 107/219 (48%), Gaps = 23/219 (10%)
Query: 81 WMVVFAIGVCTGLVGLFVDFFVRLFTQLKFGVVQTSVEECSQKGCLALSLLELLGFN--- 137
W+ + +G+ LV +D+ + Q ++ +G LL+ L +
Sbjct: 91 WIFLVLLGLLMALVSWVMDYAIAACLQ---------AQQWMSRGLNTSILLQYLAWVTYP 141
Query: 138 -LTFVFLASLLVLIEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGGLF 196
+ F A ++ P A GSGIPE+K L GV + + L+T + KV+G+ ++ G+
Sbjct: 142 VVLITFSAGFTQILAPQAVGSGIPEMKTILRGVVLKEYLTLKTFIAKVIGLTCALGSGMP 201
Query: 197 VGKEGPMIHSGSVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGA 256
+GKEGP +H S+ A L +F S+ F Y R+ + ++A A GV F A
Sbjct: 202 LGKEGPFVHIASMCAALLSKFLSL------FGGIYENESRN-TEMLAAACAVGVGCCFAA 254
Query: 257 PIGGTLFSLEEGSSFWNQGLTWKVLFCSMSATFTLNFFR 295
PIGG LFS+E S+F+ W+ F +ATF+ FR
Sbjct: 255 PIGGVLFSIEVTSTFFAVRNYWRGFF---AATFSAFIFR 290
>gi|155969705 chloride channel Kb [Homo sapiens]
Length = 687
Score = 73.2 bits (178), Expect = 3e-13
Identities = 46/142 (32%), Positives = 75/142 (52%), Gaps = 9/142 (6%)
Query: 150 IEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGG--LFVGKEGPMIHSG 207
I P + GSGIPEVK L GV + + ++ KV+G+ ++A G LF+GK GP +H
Sbjct: 114 ITPSSGGSGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLFLGKVGPFVHLS 173
Query: 208 SVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEE 267
++ A L + ++ ++ + + + + + + A AA GVA F AP G LFS+E
Sbjct: 174 VMMAAYLGRVRTTTIGEPE-------NKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEV 226
Query: 268 GSSFWNQGLTWKVLFCSMSATF 289
SS ++ W+ F + F
Sbjct: 227 MSSHFSVWDYWRGFFAATCGAF 248
>gi|112382220 chloride channel Ka isoform 1 [Homo sapiens]
Length = 687
Score = 72.8 bits (177), Expect = 4e-13
Identities = 45/142 (31%), Positives = 75/142 (52%), Gaps = 9/142 (6%)
Query: 150 IEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGG--LFVGKEGPMIHSG 207
I P + GSGIPE+K L GV + + ++ KV+G+ ++A G LF+GK GP +H
Sbjct: 114 ITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLS 173
Query: 208 SVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEE 267
++ A L + ++ ++ + + + + + + A AA GVA F AP G LFS+E
Sbjct: 174 VMIAAYLGRVRTTTIGEPE-------NKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEV 226
Query: 268 GSSFWNQGLTWKVLFCSMSATF 289
SS ++ W+ F + F
Sbjct: 227 MSSHFSVRDYWRGFFAATCGAF 248
>gi|112382222 chloride channel Ka isoform 2 [Homo sapiens]
Length = 686
Score = 72.8 bits (177), Expect = 4e-13
Identities = 45/142 (31%), Positives = 75/142 (52%), Gaps = 9/142 (6%)
Query: 150 IEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGG--LFVGKEGPMIHSG 207
I P + GSGIPE+K L GV + + ++ KV+G+ ++A G LF+GK GP +H
Sbjct: 114 ITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLS 173
Query: 208 SVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEE 267
++ A L + ++ ++ + + + + + + A AA GVA F AP G LFS+E
Sbjct: 174 VMIAAYLGRVRTTTIGEPE-------NKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEV 226
Query: 268 GSSFWNQGLTWKVLFCSMSATF 289
SS ++ W+ F + F
Sbjct: 227 MSSHFSVRDYWRGFFAATCGAF 248
>gi|13654235 regulator of G-protein signaling 20 isoform b [Homo
sapiens]
Length = 241
Score = 35.8 bits (81), Expect = 0.060
Identities = 12/17 (70%), Positives = 12/17 (70%)
Query: 2 AGCRGSLCCCCRWCCCC 18
AG RGS CC WCCCC
Sbjct: 53 AGSRGSNACCFCWCCCC 69
>gi|41281805 regulator of G-protein signaling 20 isoform a [Homo
sapiens]
Length = 388
Score = 35.8 bits (81), Expect = 0.060
Identities = 12/17 (70%), Positives = 12/17 (70%)
Query: 2 AGCRGSLCCCCRWCCCC 18
AG RGS CC WCCCC
Sbjct: 200 AGSRGSNACCFCWCCCC 216
>gi|169204828 PREDICTED: hypothetical protein [Homo sapiens]
Length = 219
Score = 34.7 bits (78), Expect = 0.13
Identities = 10/15 (66%), Positives = 10/15 (66%)
Query: 4 CRGSLCCCCRWCCCC 18
C G CCCC CCCC
Sbjct: 152 CPGCCCCCCCCCCCC 166
Score = 32.0 bits (71), Expect = 0.86
Identities = 9/15 (60%), Positives = 9/15 (60%)
Query: 4 CRGSLCCCCRWCCCC 18
C CCCC WCC C
Sbjct: 158 CCCCCCCCCCWCCSC 172
Score = 28.9 bits (63), Expect = 7.3
Identities = 9/16 (56%), Positives = 9/16 (56%)
Query: 3 GCRGSLCCCCRWCCCC 18
GC CCCC CC C
Sbjct: 154 GCCCCCCCCCCCCCWC 169
>gi|169205567 PREDICTED: hypothetical protein [Homo sapiens]
Length = 219
Score = 34.7 bits (78), Expect = 0.13
Identities = 10/15 (66%), Positives = 10/15 (66%)
Query: 4 CRGSLCCCCRWCCCC 18
C G CCCC CCCC
Sbjct: 152 CPGCCCCCCCCCCCC 166
Score = 32.0 bits (71), Expect = 0.86
Identities = 9/15 (60%), Positives = 9/15 (60%)
Query: 4 CRGSLCCCCRWCCCC 18
C CCCC WCC C
Sbjct: 158 CCCCCCCCCCWCCSC 172
Score = 28.9 bits (63), Expect = 7.3
Identities = 9/16 (56%), Positives = 9/16 (56%)
Query: 3 GCRGSLCCCCRWCCCC 18
GC CCCC CC C
Sbjct: 154 GCCCCCCCCCCCCCWC 169
>gi|169204182 PREDICTED: hypothetical protein [Homo sapiens]
Length = 220
Score = 34.7 bits (78), Expect = 0.13
Identities = 10/15 (66%), Positives = 10/15 (66%)
Query: 4 CRGSLCCCCRWCCCC 18
C G CCCC CCCC
Sbjct: 152 CPGCCCCCCCCCCCC 166
Score = 32.0 bits (71), Expect = 0.86
Identities = 9/15 (60%), Positives = 9/15 (60%)
Query: 4 CRGSLCCCCRWCCCC 18
C CCCC WCC C
Sbjct: 159 CCCCCCCCCCWCCSC 173
Score = 30.4 bits (67), Expect = 2.5
Identities = 8/10 (80%), Positives = 8/10 (80%)
Query: 9 CCCCRWCCCC 18
CCCC CCCC
Sbjct: 158 CCCCCCCCCC 167
>gi|45504382 DnaJ (Hsp40) homolog, subfamily C, member 5 [Homo
sapiens]
Length = 198
Score = 31.2 bits (69), Expect = 1.5
Identities = 16/50 (32%), Positives = 25/50 (50%), Gaps = 1/50 (2%)
Query: 4 CRGSLCCCCRWCCCCGERETRTPE-ELTILGETQEEEDEILPRKDYESLD 52
C C CC + CCCG+ + + PE E T + E+ + L + E+ D
Sbjct: 119 CYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVSPEDLEAQLQSDEREATD 168
>gi|29126218 DnaJ (Hsp40) homolog, subfamily C, member 5 beta [Homo
sapiens]
Length = 199
Score = 31.2 bits (69), Expect = 1.5
Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 3/52 (5%)
Query: 1 MAGCRGSLCCCCRWCCCCG--ERETRTPEE-LTILGETQEEEDEILPRKDYE 49
+ GC C CC CCCG E+ PEE + E EE+ + KD +
Sbjct: 120 LTGCYFCCCLCCCCNCCCGHCRPESSVPEEDFYVSPEDLEEQIKSDMEKDVD 171
>gi|37700254 triggering receptor expressed on myeloid cells-like 4
[Homo sapiens]
Length = 200
Score = 29.6 bits (65), Expect = 4.3
Identities = 10/20 (50%), Positives = 11/20 (55%)
Query: 10 CCCRWCCCCGERETRTPEEL 29
CC CCCC + PEEL
Sbjct: 9 CCFHLCCCCSWPQGAVPEEL 28
>gi|239755634 PREDICTED: hypothetical protein [Homo sapiens]
Length = 449
Score = 29.3 bits (64), Expect = 5.6
Identities = 10/18 (55%), Positives = 11/18 (61%)
Query: 4 CRGSLCCCCRWCCCCGER 21
C+ S C R CCCCG R
Sbjct: 22 CKPSAGRCARSCCCCGRR 39
>gi|239750121 PREDICTED: hypothetical protein XP_002347280 [Homo
sapiens]
Length = 402
Score = 29.3 bits (64), Expect = 5.6
Identities = 10/18 (55%), Positives = 11/18 (61%)
Query: 4 CRGSLCCCCRWCCCCGER 21
C+ S C R CCCCG R
Sbjct: 22 CKPSAGRCARSCCCCGRR 39
>gi|239744429 PREDICTED: hypothetical protein XP_002343157 [Homo
sapiens]
Length = 449
Score = 29.3 bits (64), Expect = 5.6
Identities = 10/18 (55%), Positives = 11/18 (61%)
Query: 4 CRGSLCCCCRWCCCCGER 21
C+ S C R CCCCG R
Sbjct: 22 CKPSAGRCARSCCCCGRR 39
>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
Length = 1040
Score = 28.5 bits (62), Expect = 9.5
Identities = 10/16 (62%), Positives = 10/16 (62%), Gaps = 2/16 (12%)
Query: 4 CRGSLCCCCRWCCCCG 19
C S CC C CCCCG
Sbjct: 751 CLASDCCLC--CCCCG 764
>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
Length = 896
Score = 28.5 bits (62), Expect = 9.5
Identities = 10/16 (62%), Positives = 10/16 (62%), Gaps = 2/16 (12%)
Query: 4 CRGSLCCCCRWCCCCG 19
C S CC C CCCCG
Sbjct: 751 CLASDCCLC--CCCCG 764
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.143 0.455
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,788,389
Number of Sequences: 37866
Number of extensions: 616871
Number of successful extensions: 2392
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2226
Number of HSP's gapped (non-prelim): 123
length of query: 353
length of database: 18,247,518
effective HSP length: 103
effective length of query: 250
effective length of database: 14,347,320
effective search space: 3586830000
effective search space used: 3586830000
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.