BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|24430146 nucleoporin 153kDa [Homo sapiens] (1475 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|24430146 nucleoporin 153kDa [Homo sapiens] 2928 0.0 gi|150418007 RAN binding protein 2 [Homo sapiens] 184 5e-46 gi|91982772 mucin 17 [Homo sapiens] 134 8e-31 gi|33946327 nucleoporin 214kDa [Homo sapiens] 127 1e-28 gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 100 2e-20 gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 99 2e-20 gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] 99 2e-20 gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] 99 2e-20 gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] 99 2e-20 gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] 99 2e-20 gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] 99 2e-20 gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] 99 2e-20 gi|239740645 PREDICTED: hypothetical protein [Homo sapiens] 99 2e-20 gi|239513940 PREDICTED: hypothetical protein [Homo sapiens] 99 2e-20 gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ... 99 3e-20 gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ... 92 5e-18 gi|161016767 mucin 21 [Homo sapiens] 91 1e-17 gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens] 89 4e-17 gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 87 2e-16 gi|26051278 nuclear pore membrane protein 121 [Homo sapiens] 84 8e-16 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 83 2e-15 gi|56549643 nucleoporin 98kD isoform 3 [Homo sapiens] 78 6e-14 gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 77 2e-13 gi|24497609 nucleoporin 62kDa [Homo sapiens] 75 6e-13 gi|24497607 nucleoporin 62kDa [Homo sapiens] 75 6e-13 gi|24497605 nucleoporin 62kDa [Homo sapiens] 75 6e-13 gi|24497603 nucleoporin 62kDa [Homo sapiens] 75 6e-13 gi|89276766 trophinin isoform 5 [Homo sapiens] 75 6e-13 gi|161019170 mucin 5AC [Homo sapiens] 72 5e-12 gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens] 68 7e-11 >gi|24430146 nucleoporin 153kDa [Homo sapiens] Length = 1475 Score = 2928 bits (7591), Expect = 0.0 Identities = 1475/1475 (100%), Positives = 1475/1475 (100%) Query: 1 MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN 60 MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN Sbjct: 1 MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN 60 Query: 61 KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS 120 KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS Sbjct: 61 KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS 120 Query: 121 NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN 180 NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN Sbjct: 121 NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN 180 Query: 181 ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS 240 ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS Sbjct: 181 ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS 240 Query: 241 PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS 300 PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS Sbjct: 241 PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS 300 Query: 301 YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ 360 YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ Sbjct: 301 YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ 360 Query: 361 YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ 420 YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ Sbjct: 361 YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ 420 Query: 421 RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT 480 RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT Sbjct: 421 RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT 480 Query: 481 SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL 540 SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL Sbjct: 481 SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL 540 Query: 541 PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPA 600 PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPA Sbjct: 541 PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPA 600 Query: 601 EILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGS 660 EILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGS Sbjct: 601 EILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGS 660 Query: 661 SWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFK 720 SWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFK Sbjct: 661 SWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFK 720 Query: 721 PVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVT 780 PVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVT Sbjct: 721 PVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVT 780 Query: 781 TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSG 840 TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSG Sbjct: 781 TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSG 840 Query: 841 GSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAAS 900 GSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAAS Sbjct: 841 GSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAAS 900 Query: 901 SSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFK 960 SSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFK Sbjct: 901 SSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFK 960 Query: 961 FGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSA 1020 FGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSA Sbjct: 961 FGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSA 1020 Query: 1021 GFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKG 1080 GFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKG Sbjct: 1021 GFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKG 1080 Query: 1081 GFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQ 1140 GFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQ Sbjct: 1081 GFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQ 1140 Query: 1141 TKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSS 1200 TKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSS Sbjct: 1141 TKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSS 1200 Query: 1201 STPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKL 1260 STPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKL Sbjct: 1201 STPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKL 1260 Query: 1261 ATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFG 1320 ATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFG Sbjct: 1261 ATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFG 1320 Query: 1321 ANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380 ANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ Sbjct: 1321 ANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380 Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ Sbjct: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440 Query: 1441 SPAAFTVGSNGKNVFSSSGTSFSGRKIKTAVRRRK 1475 SPAAFTVGSNGKNVFSSSGTSFSGRKIKTAVRRRK Sbjct: 1441 SPAAFTVGSNGKNVFSSSGTSFSGRKIKTAVRRRK 1475 >gi|150418007 RAN binding protein 2 [Homo sapiens] Length = 3224 Score = 184 bits (467), Expect = 5e-46 Identities = 134/432 (31%), Positives = 186/432 (43%), Gaps = 74/432 (17%) Query: 640 PAISSFSSSGIGFGESLKAG---------SSWQCDTCLLQNKVTDNKCIACQAAKLSPRD 690 P +SF ++LK+G W C +CL++N+ +C+ACQ +P Sbjct: 1516 PTPASFKFGTSETSKTLKSGFEDMFAKKEGQWDCSSCLVRNEANATRCVACQ----NPDK 1571 Query: 691 TAKQTGIETPN--KSGKT-TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACET 747 + T + P K G + T A +GF F G WDC CLV+N+ A KC+AC+ Sbjct: 1572 PSPSTSVPAPASFKFGTSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNEASATKCIACQN 1631 Query: 748 PKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNN 807 P K+ T + VS A + T+ + GF F + G W+CSVC V N Sbjct: 1632 PG-----KQNQTTSAVSTPASSETSKAPKS-------GFEGMFTKKEGQWDCSVCLVRNE 1679 Query: 808 AEDNKCVSCMSEKPGSSVPASSSSTVPVS-----LPSGGSLGLEKFKKPEGSWDCELCLV 862 A KC++C + PG +S+ + P S P G G+ F K EG WDC +CLV Sbjct: 1680 ASATKCIAC--QNPGKQNQTTSAVSTPASSETSKAPKSGFEGM--FTKKEGQWDCSVCLV 1735 Query: 863 QNKADSTKCLACE-----------------SAKPGTKSGFKGF--------------DTS 891 +N+A +TKC+AC+ KSGF+G Sbjct: 1736 RNEASATKCIACQCPSKQNQTTAISTPASSEISKAPKSGFEGMFIRKGQWDCSVCCVQNE 1795 Query: 892 SSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFK 951 SSS A + K + PS T K D G ++G S N + K Sbjct: 1796 SSSLKCVACDASKPTHKPIAEAPS-AFTLGSEMKLHDSSGSQVGTGFKS---NFSEKASK 1851 Query: 952 FSKPIGDFKFG-VSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEK 1010 F FKFG V E+ P + + S N FK G S PVS F+FG+S G +EK Sbjct: 1852 FGNTEQGFKFGHVDQENSPSFMFQGSSNTEFK-STKEGFSIPVSADGFKFGISEPGNQEK 1910 Query: 1011 KEELPKSSSAGF 1022 K E P + GF Sbjct: 1911 KSEKPLENGTGF 1922 Score = 151 bits (381), Expect = 5e-36 Identities = 156/583 (26%), Positives = 244/583 (41%), Gaps = 93/583 (15%) Query: 657 KAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFG 716 K W C CL++N+ T ++CIACQ K + NKSG + + + FG Sbjct: 1414 KKEGHWDCSICLVRNEPTVSRCIACQNTK-------------SANKSGSSFVHQASFKFG 1460 Query: 717 --DKFKPVI-----------GTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVV 763 D KP+ G WDC CLVQN+ + KC AC+ P+ K++L T + Sbjct: 1461 QGDLPKPINSDFRSVFSTKEGQWDCSACLVQNEGSSTKCAACQNPR-----KQSLPATSI 1515 Query: 764 SESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMS---EK 820 A +S T T GF D F + G W+CS C V N A +CV+C + Sbjct: 1516 PTPASFKFGTSE--TSKTLKSGFEDMFAKKEGQWDCSSCLVRNEANATRCVACQNPDKPS 1573 Query: 821 PGSSVPASSSSTVPVS----LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACES 876 P +SVPA +S S P G G+ F K EG WDC +CLV+N+A +TKC+AC++ Sbjct: 1574 PSTSVPAPASFKFGTSETSKAPKSGFEGM--FTKKEGQWDCSVCLVRNEASATKCIACQN 1631 Query: 877 AKPGTKS-GFKGFDTSSSSSNSAASSSFKFGVSSSSSG-------------PSQTLTSTG 922 PG ++ T +SS S A S G+ + G + + Sbjct: 1632 --PGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNEASATKCIACQ 1689 Query: 923 NFKFGDQGGFKIGVSSDSGSINPMSEGFK--FSKPIGDFKFGV------SSESKPEEVKK 974 N +Q + + S + GF+ F+K G + V +S +K + Sbjct: 1690 NPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNEASATKCIACQC 1749 Query: 975 DSKNDNFKFGLSSGLSNPVSLTP---FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINS 1031 SK N +S+ S+ +S P F+ GQ + ++ S+ V Sbjct: 1750 PSK-QNQTTAISTPASSEISKAPKSGFEGMFIRKGQWDCSVCCVQNESSSLKC---VACD 1805 Query: 1032 TPAPANTIVTSENKSSFNLGT---IETKSASVAPFTCKTSEAKK-EEMPATKGGFSFGNV 1087 P + + +E S+F LG+ + S S K++ ++K + T+ GF FG+V Sbjct: 1806 ASKPTHKPI-AEAPSAFTLGSEMKLHDSSGSQVGTGFKSNFSEKASKFGNTEQGFKFGHV 1864 Query: 1088 EPASLPSASVFVLGRTEEKQQE-----PVTSTSLVFG-KKADNEEPKCQPVFSFGNSEQT 1141 + + PS TE K + PV++ FG + N+E K + G Q Sbjct: 1865 DQENSPSFMFQGSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKSEKPLENGTGFQA 1924 Query: 1142 KDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQG 1184 +D + K+ + S +TF F +T+ +G Sbjct: 1925 QDISGQKNGRGVIFGQTS---------STFTFADLAKSTSGEG 1958 Score = 93.2 bits (230), Expect = 2e-18 Identities = 171/728 (23%), Positives = 250/728 (34%), Gaps = 110/728 (15%) Query: 726 WDCDTCLVQNKPEAIKCVACETPKPGT--CVKRALTLTVVSESAETMTASSSSCTVTTGT 783 W C++C ++N A KCV+C+ P V L TV + VT Sbjct: 1356 WHCNSCSLKNASTAKKCVSCQNLNPSNKELVGPPLAETVFTPKTSPENVQDRFALVTP-- 1413 Query: 784 LGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSL 843 + G W+CS+C V N ++C++C + K S S SS V + G Sbjct: 1414 --------KKEGHWDCSICLVRNEPTVSRCIACQNTK---SANKSGSSFVHQASFKFGQG 1462 Query: 844 GLEK---------FKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSS 894 L K F EG WDC CLVQN+ STKC AC++ + S + Sbjct: 1463 DLPKPINSDFRSVFSTKEGQWDCSACLVQNEGSSTKCAACQNPRK----------QSLPA 1512 Query: 895 SNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSK 954 ++ +SFKFG S +S +TL S F + G D S +E ++ Sbjct: 1513 TSIPTPASFKFGTSETS----KTLKSGFEDMFAKKEG-----QWDCSSCLVRNEA-NATR 1562 Query: 955 PIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEEL 1014 + + KP +FKFG S P S F+ G KKE Sbjct: 1563 CVA-----CQNPDKPSPSTSVPAPASFKFGTSETSKAPKS--GFE------GMFTKKEGQ 1609 Query: 1015 PKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEE 1074 S + A A + +N N +T SA P + +TS+A K Sbjct: 1610 WDCSVC--------LVRNEASATKCIACQNPGKQN----QTTSAVSTPASSETSKAPKS- 1656 Query: 1075 MPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFS 1134 GF + SV ++ + ++T + + + V + Sbjct: 1657 ------GFEGMFTKKEGQWDCSVCLV-------RNEASATKCIACQNPGKQNQTTSAVST 1703 Query: 1135 FGNSEQTKDENSSKSTFSFSMTKPSEKES------EQPAKATFAFGAQTSTTADQGAAKP 1188 +SE +K + KS F TK + A AT Q + +Q A Sbjct: 1704 PASSETSK---APKSGFEGMFTKKEGQWDCSVCLVRNEASATKCIACQCPSKQNQTTA-- 1758 Query: 1189 VFSFLNNSSSSSSTPATSAG-GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESS 1247 ++ +SS + A +G G+F S V+ A T + Sbjct: 1759 ----ISTPASSEISKAPKSGFEGMFIRKGQWDCSVCCVQNESSSLKCVACDASKPTHKPI 1814 Query: 1248 TSQSLLFSQDSKLATTSSTGTAV-TPFV--FGPGASSNNTTTSGFGFGATTTSSSAGSSF 1304 F+ S++ S+G+ V T F F AS T GF FG +S F Sbjct: 1815 AEAPSAFTLGSEMKLHDSSGSQVGTGFKSNFSEKASKFGNTEQGFKFGHVDQENSPSFMF 1874 Query: 1305 VFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGT 1364 + S F + G G S+P G S L A G Sbjct: 1875 QGSSNTEFKSTKEGFSIPVSAD-GFKFGISEP---GNQEKKSEKPLENGTGFQAQDISG- 1929 Query: 1365 VSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTP 1424 + + +FGQ S F S FQFG NF S +G F + Sbjct: 1930 -QKNGRGVIFGQTSSTFTFADLAKSTSGEGFQFGKKDPNFK--GFSGAGEKLFSSQYGKM 1986 Query: 1425 AASAQPSG 1432 A A SG Sbjct: 1987 ANKANTSG 1994 Score = 32.3 bits (72), Expect = 3.5 Identities = 23/89 (25%), Positives = 39/89 (43%) Query: 878 KPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS 937 KP S K DT S+S + SF FG S+ S +++G+F FG + + Sbjct: 2815 KPVDLSTRKEIDTDSTSQGESKIVSFGFGSSTGLSFADLASSNSGDFAFGSKDKNFQWAN 2874 Query: 938 SDSGSINPMSEGFKFSKPIGDFKFGVSSE 966 + + S G + + +G+ + G E Sbjct: 2875 TGAAVFGTQSVGTQSAGKVGEDEDGSDEE 2903 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 134 bits (336), Expect = 8e-31 Identities = 317/1477 (21%), Positives = 541/1477 (36%), Gaps = 170/1477 (11%) Query: 69 STDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTE--EPSTTSTASNYPDVL 126 S++ S + P ++ + E SS+ T T P + TE P T++ AS P Sbjct: 289 SSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVAT 348 Query: 127 TRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFS-LVKEIKDSTSQHDDDNISTTS 185 + S L+ + +++ L + S+ P + S L + + ++ + +ST Sbjct: 349 SEMST----LSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTIL 404 Query: 186 GFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGN 245 SS AS T+ ++ + EA S + ++ T+ ++ P+ + ++ S Sbjct: 405 VASSEASTTS-TIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTP 463 Query: 246 SSILKTSQLGDSPFYPGK--TTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGV 303 + + S L +P TT A+++ +++ + P P +S + V Sbjct: 464 VASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPV 523 Query: 304 TSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPP 363 SS A + + S+P+ + S ++P + + T ++ + P Sbjct: 524 ASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIP------TSTPSEGSTPLTNMPV 577 Query: 364 VQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRES 423 RL+ S + +T S E + ST E P +R + Sbjct: 578 STRLVVSSEASTTSTTPADSNTFVTTSSEASSS--------STTAEGTSMPTSTYSERGT 629 Query: 424 GFSYPNFSLPA-----ANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLP 478 + + S A+ LS+ + +S E M + S P Sbjct: 630 TITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTP 689 Query: 479 ITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEAN 538 +TS + T +S E +T S +P+++S +T TS ++ SP + + ST + Sbjct: 690 LTSMPVNTTLVASSEASTLSTTPVDTSTPVT-----TSTEASSSPTTADGASMPTSTPSE 744 Query: 539 VLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598 P + S+PV+KT S +STL ++ H+TT +C P EG Sbjct: 745 GSTPLT-----SMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCS---PTTTEGTSM 796 Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISS---FSSSGIGFGES 655 P EGS L L S + + S A +T+PV P +S SS G S Sbjct: 797 PISTPSEGSPL--LTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTS 854 Query: 656 LKAGSSWQCDTCLLQNKVTDNKCIACQAAKLS--PRDTAKQTGIETPNKSGKTTLSASGT 713 + + + T L V+ + LS P DT+ T +S TT + GT Sbjct: 855 MPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTT--SEGT 912 Query: 714 GF-----GDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAE 768 G+ P+ D T +V ++ + +T P T A + +E Sbjct: 913 SMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTS 972 Query: 769 TMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPAS 828 T++ S T + + + E S +S D+ S + S P + Sbjct: 973 IPTSTPSEGTTPLTSTPVSHTL---VANSEAST--LSTTPVDSNTPLTTSTEASSPPPTA 1027 Query: 829 SSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGF 888 +++P S PS GS L + +V + ST + T + + Sbjct: 1028 EGTSMPTSTPSEGSTPLTRM-------PVSTTMVASSETST----LSTTPADTSTPVTTY 1076 Query: 889 DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE 948 +SSSS +A +S S S P LTS ++ VSS++ +++ + Sbjct: 1077 SQASSSSTTADGTSMPTSTYSEGSTP---LTSV-------PVSTRLVVSSEASTLS--TT 1124 Query: 949 GFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSN---L 1005 S P+ SS + E + + G + S PVS T +N Sbjct: 1125 PVDTSIPVTTSTEASSSPTTAEGTSIPTSPPS--EGTTPLASMPVSTTLVVSSEANTLST 1182 Query: 1006 GQEEKKEELPKSSSAGFSFGTGVI----NSTPAPANTIVTSENKSSFNLGTIETKSASVA 1061 + K ++ S+ A T + STP +T +TS + + E + S + Sbjct: 1183 TPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTS 1242 Query: 1062 PF---TCKTSEAKKEEMPATKGGFSF-------GNVEPASLPSASVFVLGRTEEKQQEPV 1111 P T T+ A+ P T G S G+ S+P ++ V T + + Sbjct: 1243 PVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLV---TSPEASTLL 1299 Query: 1112 TSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATF 1171 T+ G + E P + G S T ST+S T + A+ Sbjct: 1300 TTPVDTKGPVVTSNEVSSSPTPAEGTSMPT-------STYSEGRTPLTSIPVNTTLVASS 1352 Query: 1172 AFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTS-----------SSN 1220 A ++T D + S+ + S+P TS G + S+ S S+ Sbjct: 1353 AISILSTTPVDNSTP------VTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTT 1406 Query: 1221 PPVATFVFGQSSNPVSSSAFGNTAESSTS----------------------QSLLFSQ-- 1256 P V++ S+ PV +S G T+ +TS +S+ S Sbjct: 1407 PVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTP 1466 Query: 1257 --DSKLATTSSTGT-AVTPFVFGPGASSNNTTTSGFGFGATTTS--SSAGSSFVFGTGPS 1311 +S+ +T S+T + +P V SS+ T G +T S S+A +S T Sbjct: 1467 VANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTV 1526 Query: 1312 AP----SASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQP--APPTFGTV 1365 A S S TP SQ +S P S+ +ST + GS P + P + Sbjct: 1527 ASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTST--YSEGSTPLTSLPVSTML 1584 Query: 1366 SSSSQPPVFGQQPSQSAFG-SGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTP 1424 SS+ P S + +T SSS GSS T + SP + T S+TP Sbjct: 1585 VVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSP--LLTSIPVSTTP 1642 Query: 1425 AASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTS 1461 AS + S P + + T + + GTS Sbjct: 1643 VASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTS 1679 Score = 117 bits (294), Expect = 6e-26 Identities = 293/1419 (20%), Positives = 499/1419 (35%), Gaps = 158/1419 (11%) Query: 69 STDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTR 128 S++ S V + + + E SS+ T +T P T PS TST V Sbjct: 2765 SSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMP----TSTPSETSTPLTSMPVNHT 2820 Query: 129 P--SLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSL-VKEIKDSTSQHDDDNISTTS 185 P S L+ + +++ + +S+ P + G + + + ++ +STT Sbjct: 2821 PVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTP 2880 Query: 186 GFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGN 245 SS AS T +TS+P S E S + ++ T+ P+ + ++ S Sbjct: 2881 VASSEASTLS-TTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVP 2939 Query: 246 SSILKTSQLGDSPFYPGK--TTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGV 303 + + S L +P TT A+++ ++ + P P R+ +S + V Sbjct: 2940 VAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPV 2999 Query: 304 TSS-----------TARRILQSLEKMSSPL-ADAKRIPSIVSSPLNSPLDRSGIDITDFQ 351 SS T+ + S E SSP A+ IP S ++PL + T Sbjct: 3000 ASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVA 3059 Query: 352 AKREKVDSQYPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKN 411 S P + T+ V P+ + + TG + Sbjct: 3060 IPEASTLSTTP------VDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVS 3113 Query: 412 MTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPV 471 TP + + + S P +++ E T S P E Sbjct: 3114 TTPVTSSAISTLSTTPVDTSTP----VTTSTEAHSSPTTSEGTSMPTSTPSEG------- 3162 Query: 472 LPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPI 531 S P+T + T S E +T S +P+++S +T + TS ++ S+P Sbjct: 3163 ----STPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPS 3218 Query: 532 VKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPE 591 T SVPV+ T S +S L S +TT ST +PP Sbjct: 3219 EGMTPLT-----------SVPVSNTPVASSEASILSTTPVDSNTPLTT--STEASSSPP- 3264 Query: 592 DCEGPFRPAEILKEGS---VLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSS 648 EG P EGS + + AS + +++ P TS V T S SS Sbjct: 3265 TAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQAS--SSP 3322 Query: 649 GIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTL 708 I G S+ + + T L + ++ +A+ LS T + T ++ + Sbjct: 3323 PIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPT 3382 Query: 709 SASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAE 768 +A GT P GT + V P V+ E T + TL S A Sbjct: 3383 TAEGTSIPTS-SPSEGTTPLASMPVSTTP----VVSSEVNTLSTTPVDSNTLVTTSTEAS 3437 Query: 769 TMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKP-GSSVPA 827 + + ++ T T GS S+ +S + S +S P +S P Sbjct: 3438 SSPTIAEGTSLPTSTTS--------EGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPV 3489 Query: 828 SSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKG 887 ++SS S + + EGS + N ST +A A Sbjct: 3490 TTSSPTNSSPTTAEVTSMPTSTAGEGSTP-----LTNMPVSTTPVASSEA---------- 3534 Query: 888 FDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMS 947 S+ S+ S++F S +SS P+ +T +G + S + S Sbjct: 3535 ---STLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSS 3591 Query: 948 EGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQ 1007 E S P D V++ ++ + S +S P+++ P + + Sbjct: 3592 EASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISE 3651 Query: 1008 EEKKEELPKSSSAGFSFGTGVINS------------TPAPANTIVTSENKSSFNLGTIET 1055 LP +S T V +S TP+ +T +T+ S+ + + E Sbjct: 3652 AGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEG 3711 Query: 1056 KSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS 1115 + S T E ++ S+P + LG T PVT Sbjct: 3712 STLSTPSVVTSTPVTTSTEAISSSATLD-STTMSVSMP-MEISTLGTTILVSTTPVT--- 3766 Query: 1116 LVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGA 1175 + ++ P V++ + + +SS +T + T P SE+ T + Sbjct: 3767 ----RFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLIS 3822 Query: 1176 QTSTTADQGAAKPVFSFLNNSSSSSSTP-ATSAGGGIFGSSTSSSNPPVATFVFGQSSNP 1234 S + A S L+ +STP TS G F S + + + + S P Sbjct: 3823 PISVMSPSEA-----STLSTPPGDTSTPLLTSTKAGSF--SIPAEVTTIRISITSERSTP 3875 Query: 1235 VSSSAFGNTAESSTSQSLLFSQ---DSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGF 1291 +++ T +S + + S D+ T ST TA TP + P A++ Sbjct: 3876 LTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTI--PVATT-------ISV 3926 Query: 1292 GATTTSSSAGSSFVFGTGPSAPSASPAF----GANQTPTFGQSQGASQPNPPGFGSISSS 1347 T S+ G++ + P S + F GA TP +++ N P S S++ Sbjct: 3927 SVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVI----TSTELNTPSTSSSSTT 3982 Query: 1348 TAL-------FPTGSQPAPPTFGTVSSSSQPP---VFGQQPSQSAFGSGTTPNSSSAFQF 1397 T+ P + AP T+ T+S++ P G S S + +TP++S++ Sbjct: 3983 TSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTT 4042 Query: 1398 GSSTTNFNFTNNSPSGVFTF-----GANSSTPAASAQPS 1431 T + + S T A+SSTP ++ S Sbjct: 4043 RPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASS 4081 Score = 114 bits (286), Expect = 5e-25 Identities = 317/1485 (21%), Positives = 532/1485 (35%), Gaps = 159/1485 (10%) Query: 25 PIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFNKNEDVCSCSTDTSEVPRWPENKED 84 P Y +GR I R T + + L N + ST+ P E Sbjct: 1681 PTSTYTEGRTPLTSITVRTTPVASSAI-STLSTTPVDNSTPVTTSTEARSSPTTSEGTSM 1739 Query: 85 HLVYADEESSNITDGRITPEPAVSN-----------TEEPSTTST-ASNYPDVLTRPSLH 132 E ++ +T ++ P +S+ T P TTST A++ P S+ Sbjct: 1740 PNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIP 1799 Query: 133 RSHLNFSML---ESPALHC-----QPSTSSAFPIGSSGFSLVKE-IKDSTSQHDDDNIST 183 S L+ M +P H + ST S P+ S+ + + S + + +I+T Sbjct: 1800 TSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAT 1859 Query: 184 TSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSL 243 ++ + I VS T + +++LS A +S + + + Sbjct: 1860 STPSEGSTALTSIPVSTTTVA-------SSETNTLSTTPAVTSTPVTTYAQVSSSPTTAD 1912 Query: 244 GNSSILKTSQLGDSPFYP---GKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS 300 G+S T + G P TT + + L +T + PV +A + Sbjct: 1913 GSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADT--RTPVTTYSQASSSPTTA 1970 Query: 301 YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDS- 359 G + T S S PL+ + S S+ +P+D S T + + Sbjct: 1971 DGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAG 2030 Query: 360 -----QYPPVQRLMTPKPVSIATNRSVYFKP---SLTP-SGEFRKTNQRIDNKCSTGYEK 410 P +R + ++T V + S TP + + TN + +T Sbjct: 2031 GTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGS 2090 Query: 411 NMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRE--RTRFVASKPLEEE--E 466 +MT E S P + P A+ +S + + V+S P+ E Sbjct: 2091 SMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTS 2150 Query: 467 MEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQM-TSPSSTGSPMF 525 M+ P+TS + T +S I+T S +P+++S +TN + +SP+++ Sbjct: 2151 MQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSM 2210 Query: 526 KFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNC 585 S+P ST +P S++ PV T+E S S+T P+ +S T V ++ Sbjct: 2211 PTSTPSEGSTPFTSMPVSTM------PVV-TSEASTLSAT--PVDTS-----TPVTTSTE 2256 Query: 586 KKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF 645 + P EG P L EG+ L S + + + +T+PV P +S Sbjct: 2257 ATSSPTTAEGTSIPTSTLSEGTTP--LTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTST 2314 Query: 646 SSSG---IGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702 +S G S+ +S + +T L + V+ + + + LS T + T ++ Sbjct: 2315 EASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQ 2374 Query: 703 SGKTTLSASGTG-----FGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRA 757 +G + +A T + + P+ +V ++ +T P T A Sbjct: 2375 AGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEA 2434 Query: 758 LTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCM 817 + +E T+ S T ++ P+ S E +S D Sbjct: 2435 SSSPTTAEGTSIPTSPPSEGTTPLASMPVSTT---PVVSSEAGT--LSTTPVDTSTPMTT 2489 Query: 818 SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFK-------KPEGSWDCELCLVQNKADSTK 870 S + SS + VP+S S GS L PE S L ++S Sbjct: 2490 STEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEAS---TLSTTPVDSNSPV 2546 Query: 871 CLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQG 930 + E + T + TS+ S S S +S + TL++T Sbjct: 2547 VTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTT-------PV 2599 Query: 931 GFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFK-FGLSSGL 989 I V++ + + + + S PI S P EV + ++S Sbjct: 2600 DTSIPVTTSTETSSSPTTAKDTSMPI----------STPSEVSTSLTSILVSTMPVASSE 2649 Query: 990 SNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFN 1049 ++ +S TP + SSS + G+ + STP +T +T+ S+ Sbjct: 2650 ASTLSTTPVDT------RTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTL 2703 Query: 1050 LGTIETKSASVAPF---TCKTSEAKKEEMPATKGGFSFGNVEPA--SLPSASVFVLGRTE 1104 L E + S P T T+ A+ P T G S P+ S P S+ V Sbjct: 2704 LANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPV 2763 Query: 1105 EKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESE 1164 + ST+ V D P + + + + ST S + T + Sbjct: 2764 ASSEASTVSTTAV-----DTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVN 2818 Query: 1165 QPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG----------GGIFGS 1214 A+ G ++T D + PV S+ +SS+P T+ G G + Sbjct: 2819 HTPVASSEAGTLSTTPVD--TSTPV----TTSTKASSSPTTAEGIVVPISTASEGSTLLT 2872 Query: 1215 STSSSNPPVATFVFGQ-SSNPVSSSAFGNTA-ESSTSQSLLFSQDSKLATTSSTGTAVTP 1272 S S PVA+ S+ PV +S T+ E S+S + ++T S T +T Sbjct: 2873 SIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTS 2932 Query: 1273 FVFG--PGASSNNTTTSGFGFGA---TTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327 + P A S +T S TTS+ A SS G S P ++P G +TP Sbjct: 2933 ILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTP--GERRTPLT 2990 Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGT 1387 S P S +S+ + P + P T T +SSS G S G+ Sbjct: 2991 SMSVSTM----PVASSEASTLSRTPADTS-TPVTTSTEASSSPTTAEGTGIPISTPSEGS 3045 Query: 1388 TPNSS-------SAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPA 1425 TP +S A S+ + +NSP T ++S TPA Sbjct: 3046 TPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPA 3090 Score = 108 bits (271), Expect = 3e-23 Identities = 301/1506 (19%), Positives = 560/1506 (37%), Gaps = 238/1506 (15%) Query: 102 TPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSA----FP 157 +P P T P++TS+ N P LTR + + + + E+ L P+ +S + Sbjct: 2318 SPPPTAEGTSMPTSTSSEGNTP--LTRMPVSTTMV--ASFETSTLSTTPADTSTPVTTYS 2373 Query: 158 IGSSGFSLVKEIKDSTSQHDDDN-------ISTTSGFSSRASDKDITVSKNTSLPPLWSP 210 S + + TS + + + +ST SS AS T +TS P S Sbjct: 2374 QAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHS-TTPVDTSTPVTTST 2432 Query: 211 EAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNSSILKTSQLGDSPFYPGKTTYGGAA 270 EA S + ++ T+ + P+ + ++ S ++ + +S+ G P T+ Sbjct: 2433 EASSSPTTAEGTSIPTSPPSEGTTPLASMPVS---TTPVVSSEAGTLSTTPVDTSTPMTT 2489 Query: 271 AAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSPLADAKRIPS 330 + S +P + +S S G T +L S+ ++P+A + + Sbjct: 2490 STEASS--------SPTTAEDIVVPISTASEGST------LLTSIPVSTTPVASPEA-ST 2534 Query: 331 IVSSPL--NSPLDRSGIDITDFQAKREKVD---SQYPPVQRLMTPKPVS---IATNRSVY 382 + ++P+ NSP+ S +I+ E S Y + PVS +A++ + Sbjct: 2535 LSTTPVDSNSPVVTS-TEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEAST 2593 Query: 383 FKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGV 442 + + T+ + +T + +M E S S ++P A+ +S + Sbjct: 2594 LSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTL 2653 Query: 443 GGGGGKMRRERTRFV--ASKPLEEEEMEVPVLP--KISLPITSSSLPTFNFSSPEITTSS 498 R T +S P E +P + S P+T+ + T ++ E +T S Sbjct: 2654 STTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLS 2713 Query: 499 PSPINSSQALTNKVQMTS-PSSTGSPMFKFSSPI---------------VKSTEANVLPP 542 +P+++S +T + +S P++ + S+P V S+EA+ + Sbjct: 2714 TTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVST 2773 Query: 543 SSIGFTFSVPVAKTAELSGSSSTLE------------------------PIISSSAHHVT 578 +++ S+PV + E S S +T E P+ SS A ++ Sbjct: 2774 TAVDT--SIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLS 2831 Query: 579 T--------VNSTNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPT 630 T V ++ + P EG P EGS L L S ++ + S A Sbjct: 2832 TTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTL--LTSIPVSTTPVASSEASTL 2889 Query: 631 ATSPVVYTRPAISS---FSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLS 687 +T+PV + P +S SS G S+ + + T L V+ +A+ LS Sbjct: 2890 STTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLS 2949 Query: 688 PRDTAKQTGIETPNKSGKTTLSASGTGF-----GDKFKPVIGTWDCDTCLVQNKPEAIKC 742 +T + T ++ + +A GT G++ P+ + ++ + Sbjct: 2950 TTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSR 3009 Query: 743 VACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSV- 801 +T P T T S+ TA + ++T + G P+ + ++ Sbjct: 3010 TPADTSTPVT--------TSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIP 3061 Query: 802 --CCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCEL 859 +S D+ S + SS + +++P+S S GS L Sbjct: 3062 EASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVP---------- 3111 Query: 860 CLVQNKADSTKCLACESAKPGTKSGFKGFDTS---SSSSNSAASSSFKFGVSSSSSGPSQ 916 V ++ ++ S P DTS ++S+ + +S + G S +S PS+ Sbjct: 3112 --VSTTPVTSSAISTLSTTP--------VDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSE 3161 Query: 917 TLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSS-ESKPEEVKKD 975 T + VSS+ +++ + S P+ SS ++ + Sbjct: 3162 GSTPLTYMPVSTM----LVVSSEDSTLS--ATPVDTSTPVTTSTEATSSTTAEGTSIPTS 3215 Query: 976 SKNDNFKFGLSSGLSNPVSLTPFQFGVSNL-------GQEEKKEELPKSSSAGFSFGTGV 1028 + ++ G++ S PVS TP +++ SSS + GT + Sbjct: 3216 TPSE----GMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSM 3271 Query: 1029 INSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKT-----SEAKKE-------EMP 1076 STP+ +T +TS S+ + + ET + S P T S+A MP Sbjct: 3272 PTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMP 3331 Query: 1077 A---TKGGFSFGNVEPASLP--SASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQP 1131 ++G N+ ++ P S+ L T PVT+++ E P Sbjct: 3332 TSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTST----------EASLSP 3381 Query: 1132 VFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFS 1191 + G S T + + + P T ++ +T + PV S Sbjct: 3382 TTAEGTSIPTSSPSEGTTPL-----------ASMPVSTTPVVSSEVNTL----STTPVDS 3426 Query: 1192 --FLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFG--NTAESS 1247 + S+ +SS+P + G + S+TS + P++ + S+ PV+SS +T Sbjct: 3427 NTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLS--IMPLSTTPVASSEASTLSTTPVD 3484 Query: 1248 TSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNN----TTTSGFGFGATTTSSSAGSS 1303 TS + S + + T++ T++ G G++ +TT A+T S++ S Sbjct: 3485 TSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDS 3544 Query: 1304 FVFGTGPSAPSASPAF-------------GANQ------TPTFGQSQGASQPNPPGFGSI 1344 F T S S+SPA G++ + T+ S AS P+ P Sbjct: 3545 NTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRS 3604 Query: 1345 SSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNF 1404 + T + S P PP T+ S+ PS+ + P S+++ + T Sbjct: 3605 TPVTTSTQSNSTPTPPEVITLPMST--------PSEVSTPLTIMPVSTTSVTISEAGTAS 3656 Query: 1405 NFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFSG 1464 ++ + V T SS+P + P S T+ + V SS G++ S Sbjct: 3657 TLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLST 3716 Query: 1465 RKIKTA 1470 + T+ Sbjct: 3717 PSVVTS 3722 Score = 105 bits (263), Expect = 2e-22 Identities = 311/1426 (21%), Positives = 509/1426 (35%), Gaps = 200/1426 (14%) Query: 101 ITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSS--AFPI 158 +T P + T S ++ S P V + P S + S + Q ST S + P+ Sbjct: 1516 LTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPL 1575 Query: 159 GSSGFSLVKEIKD-----STSQHDDDN---ISTTSGFSSRASDKDITVSKN-------TS 203 S S + + ST+ D ST + S+ A +T+S TS Sbjct: 1576 TSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTS 1635 Query: 204 LPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTL-SPSLGNSSILKTSQLGDSPFYPG 262 +P +P A S T S P + + +P+ G S T G +P Sbjct: 1636 IPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPL-TS 1694 Query: 263 KTTYGGAAAAVRQSKLRNTPYQ--APVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSS 320 T A+ S L TP PV +A+ S G + + + S Sbjct: 1695 ITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSI 1754 Query: 321 PLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVSIATNRS 380 P++ + S S+ +P+D S T +A T + SI T+ Sbjct: 1755 PVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPT-----------TAEGTSIPTST- 1802 Query: 381 VYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSS 440 +TP ++ + N S + TP + + + + PA Sbjct: 1803 --LSEGMTPLTSTPVSHTLVAN--SEASTLSTTPVDSNSPVVTSTAVSSSPTPA------ 1852 Query: 441 GVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPS 500 E T S P E S +TS + T +S E T S + Sbjct: 1853 -----------EGTSIATSTPSEG-----------STALTSIPVSTTTVASSETNTLSTT 1890 Query: 501 PINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELS 560 P +S +T Q++S +T S + ST PP + S+PV+ T S Sbjct: 1891 PAVTSTPVTTYAQVSSSPTTAD-----GSSMPTSTPREGRPPLT-----SIPVSTTTVAS 1940 Query: 561 GSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASP 620 +TL ++ + VTT + + + P +G P EGS L S ++ Sbjct: 1941 SEINTLSTTLADTRTPVTTYSQAS---SSPTTADGTSMPTPAYSEGSTP--LTSMPLSTT 1995 Query: 621 KIDSVAAQPTATSPVVYTRPAISSF---SSSGIGFGESLKAGSSWQCDTCLLQNKVTDNK 677 + S A +T+PV + PA +S SS G S++ + + T L V+ Sbjct: 1996 LVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTL 2055 Query: 678 CIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKP 737 ++ + LS +T + + T S+S T G I + L+ + P Sbjct: 2056 VVSSEGNTLSTTPVDSKTQV-----TNSTEASSSATAEGSSM--TISAPSEGSPLLTSIP 2108 Query: 738 EAIKCVACETPKPGTCVKRALTLTVVSESAETMTAS--SSSCTVTTGTL----GFGDKFK 791 + VA +P+ T L+ T V ++ +T++ SSS T GT + D+ + Sbjct: 2109 LSTTPVA--SPEAST-----LSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDR-R 2160 Query: 792 RPIGSWECSVCCVSNNA--------EDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSL 843 P+ S S V+++A D S + SS S +++P S PS GS Sbjct: 2161 TPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGST 2220 Query: 844 GLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSF 903 + +V ++A + +++ P T S +++ S +S+ Sbjct: 2221 PFTSMPVST------MPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTL 2274 Query: 904 KFGVSSSSSGP-SQTLTSTGNFKFGD----QGGFKIGVSSDSGSINPMSEGFKFSKPIGD 958 G + +S P S TL + S+++ S P +EG Sbjct: 2275 SEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTS- 2333 Query: 959 FKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSS 1018 S + P S F S+ + P + S G + Sbjct: 2334 -----SEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMP 2388 Query: 1019 SAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPAT 1078 ++ +S G+ + S P +V+SE S+ + ++T + P T T + P T Sbjct: 2389 TSTYSEGSTPLTSVPVSTMPVVSSE-ASTHSTTPVDTST----PVTTSTEASSS---PTT 2440 Query: 1079 KGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNS 1138 G S P S PS L PV++T +V ++ PV + Sbjct: 2441 AEGTSI----PTSPPSEGTTPLASM------PVSTTPVV---SSEAGTLSTTPVDT-STP 2486 Query: 1139 EQTKDENSSKSTFSFSMTKPSEKESEQ-------PAKATFAFGAQTST--TADQGAAKPV 1189 T E SS T + + P SE P T + ST T + PV Sbjct: 2487 MTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPV 2546 Query: 1190 FSFLNNSSSSSSTPATSAGGGIFGS-STSSSNPPVATFVFGQS------SNPVSSSAFGN 1242 + SSS++S TS + ST + PV+T S + PV +S Sbjct: 2547 VTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVT 2606 Query: 1243 TA-ESSTSQSLLFSQDSKLATTSSTGTAVTPFVFG--PGASSNNTTTSGFGFGA---TTT 1296 T+ E+S+S + ++T S T++T + P ASS +T S TT Sbjct: 2607 TSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTT 2666 Query: 1297 SSSAGSSFVFGTGPSAPSASPAFGANQTP---------TFGQSQGASQPNPPGFGSISSS 1347 S+ SS G S P+++P G TP S+ ++ P + +S Sbjct: 2667 STGTSSSPTTAEGSSMPTSTP--GERSTPLTNILVSTTLLANSEASTLSTTP----VDTS 2720 Query: 1348 TALFPTGSQPAPPTFGT-VSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSST----- 1401 T + + + PT S P G P S S T P +SS S+T Sbjct: 2721 TPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVS-TLPVASSEASTVSTTAVDTS 2779 Query: 1402 ---TNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAA 1444 T ++SP+ +STP+ ++ P S P N +P A Sbjct: 2780 IPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTS--MPVNHTPVA 2823 Score = 104 bits (260), Expect = 6e-22 Identities = 298/1446 (20%), Positives = 502/1446 (34%), Gaps = 147/1446 (10%) Query: 101 ITPEPAVSNTEEPSTTSTASNYP--DVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPI 158 ++ P S T+ ++T +S P +V + P+ + + P H ++S A + Sbjct: 1180 LSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTL 1239 Query: 159 GSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASDKDITVSKNTSLPP----LWSPEAER 214 +S + +TS + +T G S S + TS+P + SPEA Sbjct: 1240 STSPVDTSTPV--TTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEA-- 1295 Query: 215 SHSLSQHTATSSKKPAFNLSAFGTL-SPSLGNSSILKTSQLGDSPF--YPGKTTYGGAAA 271 S T +K P + + +P+ G S T G +P P TT ++A Sbjct: 1296 --STLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSA 1353 Query: 272 AVRQSKLRNTPYQ--APVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSPLADAKRIP 329 S L TP PV +A S G + + + S P++ + Sbjct: 1354 I---SILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVS 1410 Query: 330 SIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLM-----TPKPVSIATNRSVYFK 384 S S+ +P+D S T +A ++ + TP +N V Sbjct: 1411 SEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANS 1470 Query: 385 PSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNRE---QRESGFSYPNFSLPAA------ 435 + T S +N + ST + TP + S S S+P + Sbjct: 1471 EASTLSTTPVDSNSPVVT--STAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVAS 1528 Query: 436 ---NGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSP 492 N LS+ + + + M+ + S P+TS + T S Sbjct: 1529 SEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSS 1588 Query: 493 EITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVP 552 E T S +PI+S K Q+T+ + S S + ST P S+P Sbjct: 1589 EANTLSTTPIDS------KTQVTASTEASSSTTAEGSSMTIST-----PSEGSPLLTSIP 1637 Query: 553 VAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPAEILKEGSVLDIL 612 V+ T S +STL S V T + TP EG P EG L Sbjct: 1638 VSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTP---AEGTSMPTSTYTEGRT--PL 1692 Query: 613 KSPGFASPKIDSVAAQPTATSPVVYTRPAISSF---SSSGIGFGESLKAGSSWQCDTCLL 669 S + + S A +T+PV + P +S SS G S+ + + T L Sbjct: 1693 TSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLT 1752 Query: 670 QNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTG-----FGDKFKPVIG 724 V+ ++ +A+ LS T + T ++ + +A GT + P+ Sbjct: 1753 SIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTS 1812 Query: 725 TWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTL 784 T T + ++ + ++ P +T T VS S A +S +T + Sbjct: 1813 TPVSHTLVANSEASTLSTTPVDSNSP------VVTSTAVSSS--PTPAEGTSIATSTPSE 1864 Query: 785 GFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKP-------GSSVPASSSSTVPVSL 837 G P+ + S+ ++ P SS + S++P S Sbjct: 1865 GSTALTSIPVS----TTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTST 1920 Query: 838 PSGG-----SLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSS 892 P G S+ + + + + + S+ P T G T + Sbjct: 1921 PREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADG-TSMPTPA 1979 Query: 893 SSSNSAASSSFKFGVSSSSSGPSQTLTST-------------GNFKFGDQGGFKIGVSSD 939 S S +S + S + TL++T G+ GG I S+ Sbjct: 1980 YSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTP 2039 Query: 940 SGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQ 999 S P++ G S + G + + P + K N ++ + ++++ Sbjct: 2040 SERTTPLA-GMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPS 2098 Query: 1000 FGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANT-IVTSENKSSFNLGTIETKSA 1058 G L +P S++ S +++TP +N+ ++TS SS I T+ Sbjct: 2099 EGSPLL------TSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSS---SPIPTEGT 2149 Query: 1059 SVAPFTCKTSEAKKEEMPATKGGFSFGNVEPAS-LPSASVFVLGRTEEKQQEPVTS--TS 1115 S+ T MP + + + S P + + + E + P TS TS Sbjct: 2150 SMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTS 2209 Query: 1116 LVFGKKADNEEP-KCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFG 1174 + ++ P PV E S+ S + P +E + T A G Sbjct: 2210 MPTSTPSEGSTPFTSMPV---STMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEG 2266 Query: 1175 AQTSTTADQGAAKPVFSF-------LNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFV 1227 T+ P+ S N+ S+ ST + S+ +SS PP A Sbjct: 2267 TSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAE-- 2324 Query: 1228 FGQSSNPVSSSAFGNTAES----STSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNN 1283 +S P S+S+ GNT + ST+ F + T + T T VT + A S+ Sbjct: 2325 --GTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTY---SQAGSSP 2379 Query: 1284 TT-------TSGFGFGATTTSSSAGSSF-VFGTGPSAPSASPAFGANQTPTFGQSQGASQ 1335 TT TS + G+T +S S+ V + S S +P TP ++ +S Sbjct: 2380 TTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPV--DTSTPVTTSTEASSS 2437 Query: 1336 PNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAF 1395 P SI +S T + P T SS+ P ++ T+ +SS+ Sbjct: 2438 PTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSP 2497 Query: 1396 QFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVF 1455 T + S + T S+TP AS + S P + + T + Sbjct: 2498 TTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSAT 2557 Query: 1456 SSSGTS 1461 S+ GTS Sbjct: 2558 SAEGTS 2563 Score = 103 bits (258), Expect = 9e-22 Identities = 304/1464 (20%), Positives = 514/1464 (35%), Gaps = 132/1464 (9%) Query: 69 STDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYP--DVL 126 S + S + P + + +V ++E SS+ P PA T P++T + P + Sbjct: 1292 SPEASTLLTTPVDTKGPVVTSNEVSSS-------PTPA-EGTSMPTSTYSEGRTPLTSIP 1343 Query: 127 TRPSLHRSHLNFSMLESPALHCQPSTSS----AFPIGSSGFSLVKEI-KDSTSQHDDDNI 181 +L S + +P + P T+S + P S G S+ + T+ + Sbjct: 1344 VNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPV 1403 Query: 182 STTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSP 241 STT SS AS T +TS P S EA S + ++ + + P+ + ++ Sbjct: 1404 STTPVVSSEASTLSAT-PVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPV 1462 Query: 242 SLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSY 301 S + + S L +P A + +P + + +S S Sbjct: 1463 SNTPVANSEASTLSTTPVDSNSPVVTSTAVS-----------SSPTPAEGTSIAISTPSE 1511 Query: 302 GVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQY 361 G T+ T+ + + SS + P++ S+P+ + S T + S Y Sbjct: 1512 GSTALTSIPV-STTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQT--STY 1568 Query: 362 PPVQRLMTPKPVS-IATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNM----TPGQ 416 +T PVS + S S TP + + ST E + TP + Sbjct: 1569 SEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSE 1628 Query: 417 NREQRES-GFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKI 475 S S + P A+ LS+ + + P E M + Sbjct: 1629 GSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEG 1688 Query: 476 SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535 P+TS ++ T +S I+T S +P+++S +T TS + SP + + ST Sbjct: 1689 RTPLTSITVRTTPVASSAISTLSTTPVDNSTPVT-----TSTEARSSPTTSEGTSMPNST 1743 Query: 536 EANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEG 595 + P + S+PV+ T LS +STL ++ VTT + P EG Sbjct: 1744 PSEGTTPLT-----SIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEAT---SSPTTAEG 1795 Query: 596 PFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISS---FSSSGIGF 652 P L EG + L S + + + A +T+PV P ++S SS Sbjct: 1796 TSIPTSTLSEG--MTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAE 1853 Query: 653 GESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASG 712 G S+ + + T L V+ + + LS T + T + + +A G Sbjct: 1854 GTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADG 1913 Query: 713 TGF-----GDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767 + + P+ T + ++ + +T P T +A + ++ Sbjct: 1914 SSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGT 1973 Query: 768 ETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPA 827 T + S + ++ + S E S +S D + S + SS Sbjct: 1974 SMPTPAYSEGSTPLTSMPLSTTL---VVSSEAST--LSTTPVDTSTPATTSTEGSSSPTT 2028 Query: 828 SSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKG 887 + +++ S PS E+ G +V ++ ++ +S T S Sbjct: 2029 AGGTSIQTSTPS------ERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNS---- 2078 Query: 888 FDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMS 947 T +SSS +A SS S S P T + + + ++ Sbjct: 2079 --TEASSSATAEGSSMTISAPSEGS-PLLTSIPLSTTPVASPEASTLSTTPVDSNSPVIT 2135 Query: 948 EGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQ 1007 S PI + + + + + ++S + +S TP Sbjct: 2136 STEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNS 2195 Query: 1008 EEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPF---T 1064 E + SS S GT + STP+ +T TS S+ + T E + S P T Sbjct: 2196 TEAR------SSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTST 2249 Query: 1065 CKTSEAKKEEMPATKGGFSF-------GNVEPASLP-------SASVFVLGRTEEKQQEP 1110 T+ + P T G S G S+P ++ V L T P Sbjct: 2250 PVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTP 2309 Query: 1111 VTSTSLVFGKKADNEEPKCQP--VFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAK 1168 T TS E P S GN+ T+ S+ SF + S ++ Sbjct: 2310 FT-TSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTP 2368 Query: 1169 ATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNP-----PV 1223 T A +S T + P ++ S+ +S P ++ +ST S+ P PV Sbjct: 2369 VTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPV 2428 Query: 1224 ATFVFGQSSN--------PVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGT-AVTPFV 1274 T SS P S + G T +S S S+ T S+T TP Sbjct: 2429 TTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMT 2488 Query: 1275 FGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPS-APSASP-AFGANQTPTFGQSQG 1332 ASS+ TT +T +S GS+ + S P ASP A + TP S Sbjct: 2489 TSTEASSSPTTAEDIVVPIST--ASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPV 2546 Query: 1333 ASQPNPPGFGSISSSTAL----FPTGSQP--APPTFGTVSSSSQPPVFGQQPSQSAFGSG 1386 + + + T++ + GS P + P +SS+ P ++ Sbjct: 2547 VTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVT 2606 Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446 T+ +SS+ T+ T + S T S+ P AS++ S P + T Sbjct: 2607 TSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTT 2666 Query: 1447 VGSNGKNVFSSSGTSFSGRKIKTA 1470 S G SSS T+ G + T+ Sbjct: 2667 --STGT---SSSPTTAEGSSMPTS 2685 Score = 103 bits (256), Expect = 2e-21 Identities = 222/1055 (21%), Positives = 381/1055 (36%), Gaps = 120/1055 (11%) Query: 458 ASKPLEEEEMEVPVLPKI--SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQ-M 514 +S P E +P S P+TS T +S E T +P+ S +T Q Sbjct: 195 SSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQAS 254 Query: 515 TSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSA 574 +SP++ P S+P ST +P SV + ++E S S+T +A Sbjct: 255 SSPTTAEGPSLSNSAPSGGSTPLTRMP-------LSVMLVVSSEASTLSTT------PAA 301 Query: 575 HHVTTVNSTNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASP----KIDSVAAQPT 630 ++ + ST + P EG P EGS + +P P ++ +++ P Sbjct: 302 TNIPVITSTEASSS-PTTAEGTSIPTSTYTEGST-PLTSTPASTMPVATSEMSTLSITPV 359 Query: 631 ATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRD 690 TS +V T SS ++ S+ + + T L V+ + +A+ S Sbjct: 360 DTSTLVTTSTEPSSLPTT--AEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIP 417 Query: 691 TAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKP 750 +T + T +++ + +A T P G+ + V P A + + P Sbjct: 418 VDSKTFVTTASEASSSPTTAEDTSIATS-TPSEGSTPLTSMPVSTTPVASSEASNLSTTP 476 Query: 751 GTCVKRALTLTVVSES---AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNN 807 + T T S S AE + +S+ + + L P+ S E S +S Sbjct: 477 VDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEAST--LSTT 534 Query: 808 AEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKAD 867 D S + SS +++P S PS GS L N Sbjct: 535 PVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPL-----------------TNMPV 577 Query: 868 STKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFG 927 ST+ + S++ T S T+ + SN+ ++S + SS+++ + TST + Sbjct: 578 STRLVV--SSEASTTS------TTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYS---- 625 Query: 928 DQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSS 987 + G I S S ++ SE S D V++ ++ ++ + + Sbjct: 626 -ERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYT 684 Query: 988 GLSNPVSLTPFQFGVSNLGQEEKKEELP------------KSSSAGFSFGTGVINSTPAP 1035 S P++ P + + P SSS + G + STP+ Sbjct: 685 EGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSE 744 Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEE---MPATKGGFSFG------- 1085 +T +TS S L + E + S P T E P T G S Sbjct: 745 GSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEG 804 Query: 1086 ---------NVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKC-QPVFSF 1135 ++ P + P AS L T PVT+++ V E +S Sbjct: 805 SPLLTSIPVSITPVTSPEAS--TLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSE 862 Query: 1136 GNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNN 1195 G + T S+ + +++ S + T + A++S T +G + P + Sbjct: 863 GRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMP-----TS 917 Query: 1196 SSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFS 1255 + STP TS +S + AT V +S PV++S ++ ++ + + + Sbjct: 918 TPGEGSTPLTSMPDSTTPVVSSEARTLSATPV--DTSTPVTTSTEATSSPTTAEGTSIPT 975 Query: 1256 QDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSA 1315 TT T T V+ + +S +TT TTS+ A S G S P++ Sbjct: 976 STPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTS 1035 Query: 1316 SPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFG 1375 +P+ G+ TP + S +ST P T + +SSS G Sbjct: 1036 TPSEGS--TPLTRMPVSTTM-----VASSETSTLSTTPADTSTPVTTYSQASSSSTTADG 1088 Query: 1376 QQPSQSAFGSGTTPNS----SSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQ-- 1429 S + G+TP + S+ S + + T S T +S+ +A+ Sbjct: 1089 TSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGT 1148 Query: 1430 -----PSGSGGFPFNQSPAAFT-VGSNGKNVFSSS 1458 P G P P + T V S+ N S++ Sbjct: 1149 SIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTT 1183 Score = 96.7 bits (239), Expect = 1e-19 Identities = 224/1050 (21%), Positives = 373/1050 (35%), Gaps = 138/1050 (13%) Query: 461 PLEEEEMEVPVLPK-ISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSS 519 P E+ P P+ +P+++ S + + + ++T+ + +LT KV M++P + Sbjct: 130 PSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLT 189 Query: 520 TG-----SPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSA 574 T SP S+ I KST + P + S+P + S + TL +++ Sbjct: 190 TSTQASSSPTTPESTTIPKSTNSEGSTPLT-----SMPASTMKVASSEAITL---LTTPV 241 Query: 575 HHVTTVNSTNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSP 634 T V + + P EGP GS + + P + + S A +T+P Sbjct: 242 EISTPVTISAQASSSPTTAEGPSLSNSAPSGGST-PLTRMP-LSVMLVVSSEASTLSTTP 299 Query: 635 VVYTRPAISSFSSSG---IGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLS--PR 689 P I+S +S G S+ + + T L + + + LS P Sbjct: 300 AATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPV 359 Query: 690 DTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749 DT+ T S TT A+ + T + + N P + VA Sbjct: 360 DTSTLVTTSTEPSSLPTTAEATSM--------LTSTLSEGSTPLTNMPVSTILVASSEAS 411 Query: 750 PGTCV---KRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSN 806 + + + T S+ TA +S +T + G P+ + + SN Sbjct: 412 TTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASN 471 Query: 807 NAE---DNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQ 863 + D+K S + SS P + +++P S PS GS L + + Sbjct: 472 LSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVST------MPVAS 525 Query: 864 NKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGN 923 ++A + +++ P T +SS +++SS+ G S +S PS+ T N Sbjct: 526 SEASTLSTTPVDTSTPVT-----------TSSEASSSSTTPEGTSIPTSTPSEGSTPLTN 574 Query: 924 FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKF 983 ++ VSS++ + + + P F +S E S Sbjct: 575 MPVST----RLVVSSEASTTS--------TTPADSNTFVTTSS----EASSSSTT----- 613 Query: 984 GLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSE 1043 + G S P S + + + L SS A +++TP +NT VT+ Sbjct: 614 --AEGTSMPTST--YSERGTTITSMSVSTTLVASSEAS------TLSTTPVDSNTPVTTS 663 Query: 1044 NKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRT 1103 +++ + T E S + +T MP V + S+ L T Sbjct: 664 TEATSSSTTAEGTSMPTSTYT--EGSTPLTSMP----------VNTTLVASSEASTLSTT 711 Query: 1104 EEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNS--EQTKDENSSKSTFSFSMTKPSEK 1161 PVT+++ E P + G S T E S+ T S ++K Sbjct: 712 PVDTSTPVTTST----------EASSSPTTADGASMPTSTPSEGSTPLT-SMPVSKTLLT 760 Query: 1162 ESEQPAKATFAFGAQT----------STTADQGAAKPVF-----SFLNNSSSSSSTPATS 1206 SE +T T S T +G + P+ S L S S TP TS Sbjct: 761 SSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTS 820 Query: 1207 AGGGIFGSSTSSSNPPVATFVFGQSSN--------PVSSSAFGNTAESSTSQSLLFSQDS 1258 ++ SN PV T SS P S+ + G T +S S S Sbjct: 821 PEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATS 880 Query: 1259 KLATTSSTGTAV-TPFVFGPGASSNNTTTSGFGFGATTTS--SSAGSSFVFGTGPSAPSA 1315 ++T S+T TP A S+ TT+ G +T S+ +S T P S Sbjct: 881 AISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSE 940 Query: 1316 SPAFGAN----QTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQP 1371 + A TP ++ S P SI +ST T + P T+ ++S+ Sbjct: 941 ARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEA 1000 Query: 1372 PVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPS 1431 P S T+ +SS T+ T + S T S+T AS++ S Sbjct: 1001 STLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETS 1060 Query: 1432 GSGGFPFNQSPAAFTVGSNGKNVFSSSGTS 1461 P + S T + ++ GTS Sbjct: 1061 TLSTTPADTSTPVTTYSQASSSSTTADGTS 1090 Score = 92.0 bits (227), Expect = 4e-18 Identities = 283/1296 (21%), Positives = 464/1296 (35%), Gaps = 177/1296 (13%) Query: 89 ADEESSNITDGRI-TPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHL-NFSMLESPAL 146 A E+S ++ + T P ++ E S+ +TA ++ P R+ L + S+ P Sbjct: 2941 AGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVA 3000 Query: 147 HCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASDKDITVSKNTSLPP 206 + ST S P +S +TS + +T G S + TS+P Sbjct: 3001 SSEASTLSRTPADTS-------TPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPV 3053 Query: 207 LWSPEAERSHSLSQHTATSSKKPAFNLSAFGTL-SPSLGNSSILKTSQLGDSPF--YPGK 263 +P A S T S P + + +P+ G S + T G +P P Sbjct: 3054 STTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVS 3113 Query: 264 TTYGGAAAAVRQSKLRNTPYQA--PVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSP 321 TT ++A S L TP PV +A S G + T+ + + S+P Sbjct: 3114 TTPVTSSAI---STLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTS-----TPSEGSTP 3165 Query: 322 LADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVSIATNRSV 381 L +V S +S L + +D + PV + A S+ Sbjct: 3166 LTYMPVSTMLVVSSEDSTLSATPVDTST-------------PVTTSTEATSSTTAEGTSI 3212 Query: 382 YFKPSLTPS-GEFRKTNQRIDNKCSTGYEKNM---TPGQNREQRESGFSYPNFSLPAANG 437 P+ TPS G T+ + N E ++ TP + + + + S P A G Sbjct: 3213 ---PTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTS-TEASSSPPTAEG 3268 Query: 438 LSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFS----SPE 493 S E + + S P+ + +S +S P +S SP Sbjct: 3269 TSMPTSTPS-----EGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPP 3323 Query: 494 ITTSSPSPINS----SQALTNKVQMTSP------SSTGSPMFKFSSPIVKSTEANVLPPS 543 I + P ++ S LTN T+P S+ + S+P+ STEA++ P + Sbjct: 3324 IADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTT 3383 Query: 544 SIGFTF--SVPVAKTAELSGSSSTLEPIISSSAHHVTT--------VNSTNCKKTPPEDC 593 + G + S P T L+ + P++SS + ++T V ++ + P Sbjct: 3384 AEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIA 3443 Query: 594 EGPFRPAEILKEGSV-LDI--LKSPGFASPKIDSVAAQPTATS-PVVYTRPAISSFSSSG 649 EG P EGS L I L + AS + +++ P TS PV + P SS +++ Sbjct: 3444 EGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAE 3503 Query: 650 IGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLS 709 + S+ ++ + T L V+ + +A+ LS T + + +++ + + Sbjct: 3504 V---TSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPAT 3560 Query: 710 ASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGT-CVKRALTLTVVSESAE 768 T P G+ T L+ + + E P T V R+ +T ++S Sbjct: 3561 LQVTTMRMS-TPSEGSSSLTTMLLSST----YVTSSEASTPSTPSVDRSTPVTTSTQSNS 3615 Query: 769 TMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCV--------SNNAEDNKCVSCMSEK 820 T T V T + + P+ S V S D S + Sbjct: 3616 TPTPPE----VITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQ 3671 Query: 821 PGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPG 880 SS +T+P+ PS GS P + V + ST L+ S Sbjct: 3672 VSSSPVTPEGTTMPIWTPSEGST-------PLTTMPVSTTRVTSSEGST--LSTPSVVTS 3722 Query: 881 TKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDS 940 T SSS++ + + S + S+ G + +++T +F + I S Sbjct: 3723 TPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTS 3782 Query: 941 GSINPMSEGFKFSKPI-GDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVS-LTPF 998 S+ SEG + G +S+ S+ + L++ L +P+S ++P Sbjct: 3783 MSMTTASEGSSSPTTLEGTTTMPMSTTSERSTL------------LTTVLISPISVMSPS 3830 Query: 999 QFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI---VTSENKSSFNLGTIET 1055 + + + L S+ AG SF S PA TI +TSE + + T Sbjct: 3831 EASTLSTPPGDTSTPLLTSTKAG-SF------SIPAEVTTIRISITSERSTPLTTLLVST 3883 Query: 1056 K------SASVAP---------FTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVL 1100 AS+A FT T A +P S + S P ++F+ Sbjct: 3884 TLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATT-ISVSVITEGSTPGTTIFI- 3941 Query: 1101 GRTEEKQQEPVTS-TSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTK-- 1157 PVTS T+ VF PV + T +SS +T SFS TK Sbjct: 3942 ------PSTPVTSSTADVFPATTGAVST---PVIT-STELNTPSTSSSSTTTSFSTTKEF 3991 Query: 1158 --PSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPAT------SAGG 1209 P+ + T + T T +G + S+ +ST T S+ Sbjct: 3992 TTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSES 4051 Query: 1210 GIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTA 1269 + TS + PP TF SS P ++SA T ++ TTS Sbjct: 4052 SRPSTITSHTIPP--TFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVT 4109 Query: 1270 VTPFVFGPGASSNNT-------TTSGFGFGATTTSS 1298 T SN T TT+ FG G T+S Sbjct: 4110 TTAVPTNTTIKSNPTSTPTVPRTTTCFGDGCQNTAS 4145 Score = 35.8 bits (81), Expect = 0.31 Identities = 54/249 (21%), Positives = 90/249 (36%), Gaps = 45/249 (18%) Query: 69 STDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYP---DV 125 STDT+ P P V S IT+G TP + P T+STA +P Sbjct: 3909 STDTASTPTIP-------VATTISVSVITEGS-TPGTTIFIPSTPVTSSTADVFPATTGA 3960 Query: 126 LTRPSLHRSHLNFSMLESPALHCQPSTSSAF---------PIGSSGFSLVKEIKDSTSQ- 175 ++ P + + LN S + ST+ F P+ S +TS+ Sbjct: 3961 VSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRG 4020 Query: 176 --------------HDDDNISTTSGFSSRASDKDITVSKNT----------SLPPLWSPE 211 H +++T S S + T++ +T S PP S Sbjct: 4021 CTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSAS 4080 Query: 212 AERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNSSILKTSQLGDSPFYPGKTTYGGAAA 271 + + + T T+ KP+ ++F T++ + ++ S +P P TT G Sbjct: 4081 STTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPRTTTCFGDGC 4140 Query: 272 AVRQSKLRN 280 S+ +N Sbjct: 4141 QNTASRCKN 4149 >gi|33946327 nucleoporin 214kDa [Homo sapiens] Length = 2090 Score = 127 bits (318), Expect = 1e-28 Identities = 268/1096 (24%), Positives = 392/1096 (35%), Gaps = 187/1096 (17%) Query: 507 ALTNKVQMTSPSSTGSPMFKFSSPIV-KSTEANVLPPSSIGFTFSVPVAK-TAELSGSSS 564 A ++ V +SP G+ + +S I+ + ++ +L ++ P +A + +++ Sbjct: 1036 AKSHLVHGSSPGVMGTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAA 1095 Query: 565 TLEPIISSSAHHVTTVNSTNCKKTPP-----EDCEGPFRPAEILKEGSVLDILKSPGFAS 619 L ++S A V T+ + K P E P P+ + K+P Sbjct: 1096 ALRRQMASQAPAVNTLTESTLKNVPQVVNVQELKNNPATPSTAMGSSVPYSTAKTP---H 1152 Query: 620 PKIDSVAAQPTATSPVVYT-RPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKC 678 P + VAA ++ + +P+ + +S + G+ T ++ VT Sbjct: 1153 PVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASG-------TAKIETAVTSTPS 1205 Query: 679 IACQAAK---LSPRDTAKQTGIETPNKSGKTTLSASGT------GFGDKFKPVIGTWDCD 729 + Q +K SP T GI TP S T + T D F G+ Sbjct: 1206 ASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSY 1265 Query: 730 TCLVQNKPEA-IKCVACETP-KPGTCVKRALT-----LTVVSESAETMTASSSSCTVTTG 782 + ++ P + I + TP +P R + L+ S ET + + Sbjct: 1266 EAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSS 1325 Query: 783 TLG--FGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSG 840 G G +G + S +N A S K S VP+ + T P L Sbjct: 1326 LAGETLGSFSGLRVGQADDSTK-PTNKASSTSLTSTQPTKT-SGVPSGFNFTAPPVLG-- 1381 Query: 841 GSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAAS 900 + + P S + A ST A + P T +G G + +S SA Sbjct: 1382 -----KHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGK 1436 Query: 901 SSFKFGVSSSSS-----GPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKP 955 +SF FG ++S P T +T F +SS + PMS G + Sbjct: 1437 TSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEA 1496 Query: 956 I--------GDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQ 1007 GD + S+ S EE + S PV P VSN G Sbjct: 1497 TSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQP---AVSNSGT 1553 Query: 1008 EEKKEELPKSSSAGFSFGTGV----------INSTPAPANTIVTSENKSSFNLGTIETKS 1057 L S+ TGV +S P T VT+ SS +ET S Sbjct: 1554 AASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETSS 1613 Query: 1058 ASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLV 1117 +A T A +FG V S SVF Q P S+S Sbjct: 1614 TPIASSTTSIVAPGPSAEAA-----AFGTVTSGS----SVFA--------QPPAASSSSA 1656 Query: 1118 FGKKADNEE--PKCQPVFS--FGNSEQTKDENSSKSTFSFSMTKPSEKES--EQPAKATF 1171 F + +N P PVF ++ + + ST S + P S PA T Sbjct: 1657 FNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTT 1716 Query: 1172 AFGAQTSTTADQGA--------AKPVFSFLNNSSSS--------SSTPATSAGGGIFGSS 1215 A G TT Q + A VFSF SS SSTP TS G +FG++ Sbjct: 1717 APGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTP-TSTSGSVFGAA 1775 Query: 1216 TSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKL--ATTSSTGTAVTP- 1272 +S+S+ ++F FGQSS FG + + QS F Q + T+++T TA T Sbjct: 1776 SSTSSS--SSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSG 1833 Query: 1273 --FVFGPGASSNNT--------TTSGFGFGATTTSSSA----------GSSFVFGTG--P 1310 F G S+NT +T G FG ++SSS G F G G P Sbjct: 1834 FSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKP 1893 Query: 1311 SAP--------SASPAFGANQTP------------TFG----QSQGASQPN---PPGFGS 1343 S SAS FG+ T TFG S G +P G GS Sbjct: 1894 SQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGS 1953 Query: 1344 ISSSTALFPT-------GSQP---APPTFGTVSSSSQPPVFGQQPSQSA---------FG 1384 ++S F + G+ P +PPTFG P FG P+ ++ FG Sbjct: 1954 VASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFG 2013 Query: 1385 SGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGA-NSSTPAASAQPSGSGGFPFNQSPA 1443 GT S+ F FGSS+ +F + TFG+ + T Q SG G F Sbjct: 2014 EGTAAASAGGFGFGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSG--FGSGTG 2071 Query: 1444 AFTVGSNGKNVFSSSG 1459 F+ GSN +V G Sbjct: 2072 GFSFGSNNSSVQGFGG 2087 Score = 124 bits (312), Expect = 5e-28 Identities = 291/1292 (22%), Positives = 449/1292 (34%), Gaps = 255/1292 (19%) Query: 177 DDDNISTTSGFS---------SRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSK 227 D D +S+TS S + D + V P + +P + S L H A +K Sbjct: 980 DLDEVSSTSSVSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPS--LLPHAAPFAK 1037 Query: 228 KPAFNLSAFGTLSPSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPV 287 + S+ G + S+ S+ Q DS KT GA + A + Sbjct: 1038 SHLVHGSSPGVMGTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAAL 1097 Query: 288 RRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDI 347 RRQM ++ + + +T ST + + Q + + + K P+ S+ + S + Sbjct: 1098 RRQMASQAPAVNT--LTESTLKNVPQVVN-----VQELKNNPATPSTAMGSSV------- 1143 Query: 348 TDFQAKREKVDSQYPPVQRLMTPKPV--SIATNRSVYFK--PSLTPSGEFRKTNQRIDNK 403 P TP PV +A N++ SL PSG + Q Sbjct: 1144 ---------------PYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGD 1188 Query: 404 CSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGV-----------GGGGGKMRRE 452 ++G K T + FS P P+ G + G+ G +E Sbjct: 1189 KASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKE 1248 Query: 453 RTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSP-SPINSSQALTNK 511 ++ A + +P+ S P +S P ++S P +P ++ + T+ Sbjct: 1249 SSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGTALSTTSS 1308 Query: 512 VQMTSPSSTGSPMF----------KFSSPIVKSTEANVLPP---SSIGFTFSVPVAKTAE 558 T PS G +F FS V + + P SS T + P + Sbjct: 1309 KLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGV 1368 Query: 559 LSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFA 618 SG + T P++ T ++T PP Sbjct: 1369 PSGFNFTAPPVLGKHTEPPVTSSATTTSVAPP---------------------------- 1400 Query: 619 SPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGF-GESLKAGSSWQCDTCLLQNKVTDNK 677 AA T+++ V + P S+ SS I F G SL AG T Sbjct: 1401 -------AATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGK-------------TSFS 1440 Query: 678 CIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKP 737 + Q P T TP + TLS FG T ++ Sbjct: 1441 FGSQQTNSTVPPSAPPPTTAATPLPTSFPTLS-----FGSLLSSAT-TPSLPMSAGRSTE 1494 Query: 738 EAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSW 797 EA E P A +L +SA+ A + G+ Sbjct: 1495 EATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTA 1554 Query: 798 ECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVP-------VSLPSGGSLGLEKFKK 850 S V+ +AE + + + +VP +SS +VP ++ S G + +E Sbjct: 1555 ASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETSST 1614 Query: 851 PEGSWDCELCLVQNKADSTKCLACES-----AKPGTKSGFKGFDTSSSSSNSAASSSFKF 905 P S + A++ S A+P S F+ ++++ +A S++ F Sbjct: 1615 PIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSATPVF 1674 Query: 906 GVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSS 965 G ++S+ PS FG Q G ++ + + P FS P FG ++ Sbjct: 1675 GQVAASTAPS---------LFGQQ----TGSTASTAAATPQVSSSGFSSP----AFGTTA 1717 Query: 966 ESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFG 1025 P FG + GQ + S+++ FSF Sbjct: 1718 -------------------------------PGVFGQTTFGQASVFGQSASSAASVFSFS 1746 Query: 1026 TGVINSTPA---PANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGF 1082 +S PA PA++ TS + S F + + S+S + + P T GG Sbjct: 1747 QPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSF---------SFGQSSPNTGGGL 1797 Query: 1083 SFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK 1142 FG + + F G + T+T+ G CQ FG+S Sbjct: 1798 -FGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSF------CQ-ASGFGSSNTGS 1849 Query: 1143 DENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSS---S 1199 + ST + S S FG + + G FS L S + Sbjct: 1850 VFGQAASTGGIVFGQQSSSSSGS------VFG-----SGNTGRGGGFFSGLGGKPSQDAA 1898 Query: 1200 SSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSK 1259 + P +SA GG FGS+ +S+ + +FG S + FG A SS F + Sbjct: 1899 NKNPFSSASGG-FGSTATSN----TSNLFGNS----GAKTFGGFASSS------FGEQKP 1943 Query: 1260 LATTSSTGTAVTPFVFGPGASSNNTTTSGFG----FGATTTSSSAGSSFVFGTGP---SA 1312 T SS G +V FG S+ T GFG FG+ T G S FG P SA Sbjct: 1944 TGTFSSGGGSVASQGFG---FSSPNKTGGFGAAPVFGSPPT---FGGSPGFGGVPAFGSA 1997 Query: 1313 PSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPP 1372 P+ + G+ FG+ A+ GFGS S++T+ SQ A PTFG S S Q Sbjct: 1998 PAFTSPLGSTGGKVFGEGTAAASAGGFGFGSSSNTTSFGTLASQNA-PTFG--SLSQQTS 2054 Query: 1373 VFGQQPSQ-SAFGSGTTPNSSSAFQFGSSTTN 1403 FG Q S S FGSGT F FGS+ ++ Sbjct: 2055 GFGTQSSGFSGFGSGT-----GGFSFGSNNSS 2081 Score = 104 bits (259), Expect = 7e-22 Identities = 189/729 (25%), Positives = 271/729 (37%), Gaps = 127/729 (17%) Query: 824 SVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKS 883 + P++ S+ P + SGG PE S + N A S++P S Sbjct: 1242 ATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEP--AASSSRPVAPS 1299 Query: 884 GFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSI 943 G T+SS + S + SS +G +TL S + G + S + Sbjct: 1300 G-TALSTTSSKLETPPSKLGELLFPSSLAG--ETLGSFSGLRVGQADDSTKPTNKASSTS 1356 Query: 944 NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQ---F 1000 ++ K S F F + P + K ++ ++ ++ P + + F Sbjct: 1357 LTSTQPTKTSGVPSGFNF-----TAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVF 1411 Query: 1001 G---VSNLGQEEKKEELPKSSSAG---FSFGTGVINST---PAPANTIVTSENKSSF--- 1048 G V++ G S SAG FSFG+ NST AP T + +SF Sbjct: 1412 GSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTL 1471 Query: 1049 NLGTIETKSASVA-PFTC--KTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEE 1105 + G++ + + + + P + T EA +P K G S + ASL EE Sbjct: 1472 SFGSLLSSATTPSLPMSAGRSTEEATSSALPE-KPGDSEVSASAASL----------LEE 1520 Query: 1106 KQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTK--PSEKES 1163 +Q + E QP S + + + S + T P + Sbjct: 1521 QQSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTE 1580 Query: 1164 EQPAKATFAFGAQTSTTADQ-GAAKPVFSFLNNSSSSSST-----PATSAGGGIFGSSTS 1217 P ++F+ QT+ TA +A PV +++ +SST P SA FG+ TS Sbjct: 1581 AVPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTS 1640 Query: 1218 SSN-----------------------PPVATFVFGQ------------------------ 1230 S+ P AT VFGQ Sbjct: 1641 GSSVFAQPPAASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAAT 1700 Query: 1231 ---SSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPF---------VFGPG 1278 SS+ SS AFG TA Q+ F Q S ++S+ +V F FG Sbjct: 1701 PQVSSSGFSSPAFGTTAPGVFGQT-TFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQP 1759 Query: 1279 ASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNP 1338 ASS T+TSG FGA +++SS+ SSF FG S + FG + P FGQS G Q Sbjct: 1760 ASSTPTSTSGSVFGAASSTSSS-SSFSFGQS-SPNTGGGLFGQSNAPAFGQSPGFGQGGS 1817 Query: 1339 PGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFG 1398 FG S++T T G SS+ VFGQ S G +SSS FG Sbjct: 1818 V-FGGTSAATTTAATSGFSFCQASG-FGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFG 1875 Query: 1399 SSTTNFNFTNNSPSGVFT-FGANSSTPAASAQP--SGSGGFPFNQSPAAFTVGSNGKNVF 1455 S T G F+ G S AA+ P S SGGF T SN N+F Sbjct: 1876 SGNT------GRGGGFFSGLGGKPSQDAANKNPFSSASGGF-------GSTATSNTSNLF 1922 Query: 1456 SSSGTSFSG 1464 +SG G Sbjct: 1923 GNSGAKTFG 1931 Score = 48.5 bits (114), Expect = 5e-05 Identities = 91/405 (22%), Positives = 150/405 (37%), Gaps = 58/405 (14%) Query: 1086 NVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDEN 1145 +++P+ LP A+ F V TS+ K P + TK Sbjct: 1023 SIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVA------TSASKIIPQGADSTMLATKTVK 1076 Query: 1146 SSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLN--NSSSSSSTP 1203 + S ++ P + + + A A T + K V +N ++ +TP Sbjct: 1077 HGAPSPSHPISAP-QAAAAAALRRQMASQAPAVNTLTESTLKNVPQVVNVQELKNNPATP 1135 Query: 1204 ATSAGGGIFGSSTSSSNP---PVA------------------TFVFGQSSNPVSSSAFGN 1242 +T+ G + S+ + +P PVA T GQ S+ +S Sbjct: 1136 STAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASGTAK 1195 Query: 1243 TAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS 1302 + TS Q SK + S +GT + P SSN T GAT ++ + Sbjct: 1196 IETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQ----GATPSTKESSQ 1251 Query: 1303 SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF 1362 F +G + + A + P+ S + P P + SSS + P+G+ Sbjct: 1252 PDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEP---AASSSRPVAPSGT-----AL 1303 Query: 1363 GTVSS--SSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGAN 1420 T SS + P G+ S+ +G T S S + G + + TN + Sbjct: 1304 STTSSKLETPPSKLGELLFPSSL-AGETLGSFSGLRVGQADDSTKPTNKA---------- 1352 Query: 1421 SSTPAASAQPSGSGGFP--FNQSPAAFTVGSNGKNVFSSSGTSFS 1463 SST S QP+ + G P FN + A +G + + +SS T+ S Sbjct: 1353 SSTSLTSTQPTKTSGVPSGFNFT-APPVLGKHTEPPVTSSATTTS 1396 Score = 47.4 bits (111), Expect = 1e-04 Identities = 102/424 (24%), Positives = 159/424 (37%), Gaps = 77/424 (18%) Query: 963 VSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGF 1022 + S+ E D +D+ G+ +N V +T +S+ L S+ G Sbjct: 343 LEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEIT-----ISDEKTLPPAPVLMLLSTDGV 397 Query: 1023 SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGF 1082 +IN P + I T E S G + KS P T +S+A +++ A+ Sbjct: 398 LCPFYMINQNPGVKSLIKTPERLSLE--GERQPKSPGSTPTTPTSSQAP-QKLDASAAA- 453 Query: 1083 SFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK 1142 PASLP +S P+ + SL+ A VFSFG+S Sbjct: 454 -----APASLPPSS----------PAAPIATFSLLPAGGAPT-------VFSFGSSSLKS 491 Query: 1143 DENSSKSTFSFSMTKPSEKESEQPAKATFAF-GAQTSTTADQGAAKPVFSFLNNSSSSSS 1201 + S+S S K + P +TF+F ++ A AA PV Sbjct: 492 SATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPV------------ 539 Query: 1202 TPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESST---SQSLLFSQDS 1258 A SA FGSS F S PV S + N A + S S + S Sbjct: 540 --APSAASFSFGSS---------GFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLS 588 Query: 1259 KLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPA 1318 + T ++T T V+ +S + S F ++ + +A T SAP +S Sbjct: 589 EKFTAAATSTPVS-------SSQSAPPMSPF---SSASKPAASGPLSHPTPLSAPPSSVP 638 Query: 1319 FGAN--QTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQ 1376 ++ +P+ +QG+S P P + S + P ++P P + S QP V + Sbjct: 639 LKSSVLPSPSGRSAQGSSSPVP---SMVQKSPRITPPAAKPGSPQ----AKSLQPAVAEK 691 Query: 1377 QPSQ 1380 Q Q Sbjct: 692 QGHQ 695 Score = 43.9 bits (102), Expect = 0.001 Identities = 47/174 (27%), Positives = 70/174 (40%), Gaps = 15/174 (8%) Query: 1255 SQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPS 1314 S + +AT S P VF G+SS ++ + G + +S S S G GPS S Sbjct: 462 SPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFS 521 Query: 1315 ASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF-GTVSSSSQPPV 1373 P A+ PT P ++ S A F GS PT T S P Sbjct: 522 FVPPSKASLAPT------------PAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPN 569 Query: 1374 FGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAAS 1427 +PS S N S F +++T + + ++P + +++S PAAS Sbjct: 570 IAMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPP--MSPFSSASKPAAS 621 Score = 42.0 bits (97), Expect = 0.004 Identities = 71/308 (23%), Positives = 108/308 (35%), Gaps = 25/308 (8%) Query: 1124 NEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQ 1183 N+ P + + + E KS S T S S+ P K + A ++ Sbjct: 405 NQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTS---SQAPQKLDASAAAAPASLPPS 461 Query: 1184 GAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNT 1243 A P+ +F + + T + + S+T + PP SS SS A Sbjct: 462 SPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPP------SYSSGSDSSKAAPGP 515 Query: 1244 AESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSS 1303 S+ S F SK + + A +P P A+S + +SGF +T + S+ Sbjct: 516 GPSTFS----FVPPSKASLAPTP--AASPVA--PSAASFSFGSSGFKPTLESTPVPSVSA 567 Query: 1304 FVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFG 1363 PS P ++ A N + F A+ P S S+ + P S P G Sbjct: 568 PNIAMKPSFPPSTSAVKVNLSEKF---TAAATSTP--VSSSQSAPPMSPFSSASKPAASG 622 Query: 1364 TVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSST 1423 +S P PS S P+ S GSS+ + SP S Sbjct: 623 PLS---HPTPLSAPPSSVPLKSSVLPSPSGRSAQGSSSPVPSMVQKSPRITPPAAKPGSP 679 Query: 1424 PAASAQPS 1431 A S QP+ Sbjct: 680 QAKSLQPA 687 Score = 34.3 bits (77), Expect = 0.91 Identities = 41/146 (28%), Positives = 59/146 (40%), Gaps = 17/146 (11%) Query: 1323 QTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF---GTVSSSSQPPVFGQQPS 1379 +TP +G QP PG ST PT SQ AP + +S PP P Sbjct: 415 KTPERLSLEGERQPKSPG------STPTTPTSSQ-APQKLDASAAAAPASLPPSSPAAPI 467 Query: 1380 QSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFN 1439 + F + + F FGSS+ + T ++ G++SS A PS P + Sbjct: 468 -ATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPS 526 Query: 1440 Q-----SPAAFTVGSNGKNV-FSSSG 1459 + +PAA V + + F SSG Sbjct: 527 KASLAPTPAASPVAPSAASFSFGSSG 552 >gi|239743293 PREDICTED: mucin 12 [Homo sapiens] Length = 5478 Score = 99.8 bits (247), Expect = 2e-20 Identities = 338/1582 (21%), Positives = 542/1582 (34%), Gaps = 292/1582 (18%) Query: 69 STDTSEVPRWPE----NKEDHLVYADEES-------SNITDGRITPEPAVSNTEEPSTTS 117 ST+T+ +P P +++ Y S + T ++ E + S+++ ST + Sbjct: 2504 STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT 2563 Query: 118 TASNYPDVLTRPSLHR----SH-----LNFSML-----------ESPALHCQP-STSSAF 156 TA +PD T P L R SH + ++L ES H P ST +A Sbjct: 2564 TA--FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTAL 2621 Query: 157 PIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASDKDIT-----VSKNTSLP-PLWSP 210 GS+ + + ++ST+ H + T+ F + I V +T P SP Sbjct: 2622 SPGST--TALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSP 2679 Query: 211 EAERSHSLSQHTATSSKKPAFNLSAFGTLSP-SLGNSSILKTSQLGDSPFYPGKTTYGGA 269 + S L + T PA S T SP S + + +++ SP T + + Sbjct: 2680 ASSTSPGLQGESTTFQTHPA---STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPAS 2736 Query: 270 AAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRI------LQSLEKMSSPLA 323 + S+ + +P + + G ST RI + +L ++ Sbjct: 2737 STTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPG 2796 Query: 324 DAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVSIAT------ 377 ++ + SSP + S +T E S+ P T P S T Sbjct: 2797 LSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEE 2856 Query: 378 NRSVYFK-PSLTPSGEF-RKTNQRIDNKCSTGY-------------EKNMTPGQNREQRE 422 + +VY P T + F R T + + T + E + T G E Sbjct: 2857 STTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEEST- 2915 Query: 423 SGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSS 482 ++P GL + + + E T F +S + P S + S Sbjct: 2916 ---AFPGSPASTQTGLPATLTTAD--LGEESTTFPSSSGSTGTTLS-PARSTTSGLVGES 2969 Query: 483 SLPTFNFSSPEITTSSPSPIN---SSQALTNKVQMTSPSSTGSPMFKFSSPIVK------ 533 + + SS E TT SP S ++ T SP +T SP SS + + Sbjct: 2970 TPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSH 3029 Query: 534 ----STEANVLPPSSIGFTFS-VPVAKTAELSGSSSTLEP---IISSSAHHVTTVNSTNC 585 ST P S+ S P A + + +TL P SS TT +S+ Sbjct: 3030 SQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSS-- 3087 Query: 586 KKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF 645 P D E P + + G V ++P S + T +P Sbjct: 3088 ----PGDTETTLLPDDTITSGLV-------EASTPTHSSTGSLHTTLTPA---------- 3126 Query: 646 SSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIET-----P 700 SS+ G E SW + P TA + T P Sbjct: 3127 SSTSAGLQEESTTFQSWPSSS---------------DTTPSPPGTTAAPVEVSTTYHSRP 3171 Query: 701 NKSGKTTLSASGTGFGDKFKPVI---GTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRA 757 + + T SAS T G + T L + V T P + Sbjct: 3172 SSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSP---ISSG 3228 Query: 758 LTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCM 817 T T + T S T + D P + V S + + Sbjct: 3229 STETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHT 3288 Query: 818 SEKPGS--------------SVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQ 863 + PGS S P S+ +T+ + SLG E G E L+ Sbjct: 3289 TAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLP 3348 Query: 864 NKADSTKCL-ACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTG 922 + ++ L A T S + S++ S++F+ +S + P+ T++ Sbjct: 3349 DNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSA 3408 Query: 923 NFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFK 982 + S S S P + S +G + + S P + + Sbjct: 3409 FVELST-------TSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVAT---ATTPSPA 3458 Query: 983 FGLSSGL--------SNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPA 1034 +SGL S+P S F S+ +E SS T I+S P+ Sbjct: 3459 RSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSST-----THTISSAPS 3513 Query: 1035 PANTIV---TSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPAS 1091 + +V TS + S + T +S + S A AT G + + Sbjct: 3514 TTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDAT------GTIVLPA 3567 Query: 1092 LPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTF 1151 + SV +LG E P++S S+ E P S T + +TF Sbjct: 3568 RSTTSV-LLG---ESTTSPISSGSM---------ETTALP-----GSTTTPGLSEKSTTF 3609 Query: 1152 SFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGI 1211 S P+ S PA T + ++ STT+ ++P S+ +++ P ++ G+ Sbjct: 3610 HSSPRSPATTLS--PASTTSSGVSEESTTSH---SRP------GSTHTTAFPDSTTTPGL 3658 Query: 1212 FGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSST----G 1267 ST+S + P +T + P S++ G++ ES+TS S S D+ L+ S+T G Sbjct: 3659 SRHSTTSHSSPGST---DTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFG 3715 Query: 1268 TAVTPFVFGPGAS-----SNNTTTSGFGFGATTTSSSAGS-----SFVFGTGPSAPSASP 1317 T F PG++ ++TT+SG +T SS GS S T P S Sbjct: 3716 QESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGEST 3775 Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSI-------------SSSTALFPTGS--------- 1355 AF + T + P+PP + S+ T FP S Sbjct: 3776 AFQTHPASTH------TTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKS 3829 Query: 1356 ---QPAPPTFGTVSSSSQPPVFGQQPSQSAF------------GSGTTPNSSSAFQFGSS 1400 +P GT SS+ G+ S ++ GS TTP S A S Sbjct: 3830 TIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYS 3889 Query: 1401 TTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT---VGSNGKNVFSS 1457 + T SP+ + + G + + +QP G SPA+ T + V+SS Sbjct: 3890 SPRSPTTTLSPASMTSLGVGEESTTSRSQP---GSTHSTVSPASTTTPGLSEESTTVYSS 3946 Query: 1458 S----GTSFSGRKIKTAVRRRK 1475 S T+ R T+VRR + Sbjct: 3947 SPGSTETTVFPRSTTTSVRREE 3968 Score = 97.4 bits (241), Expect = 9e-20 Identities = 312/1492 (20%), Positives = 506/1492 (33%), Gaps = 229/1492 (15%) Query: 94 SNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHR----SHLNFSMLESPALHC- 148 ++ T ++ E S + ST +TA +PD T P L R SH + ++ L Sbjct: 983 ASTTSSGVSEESTTSRSRPGSTHTTA--FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAS 1040 Query: 149 -------QPSTSSAFPIGSSGFSL-------VKEIKDSTSQHDDDNISTTSGFSSRASDK 194 Q ST+S GS+ +L + ++ST+ H + + T+ F + Sbjct: 1041 TTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSS 1100 Query: 195 DITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS----PSLGNSSILK 250 I + SP S + S + AF T + PS + + + Sbjct: 1101 GIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEE 1160 Query: 251 TSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARR 310 ++ SP T + ++ S+ + +P + + G ST R Sbjct: 1161 STTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR 1220 Query: 311 I------LQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPV 364 I + +L ++ ++ + SSP + S +T E S+ P Sbjct: 1221 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 1280 Query: 365 QRLMTPKPVSIAT------NRSVY-----------FKPSLTPSGEFRKTNQRIDNKCSTG 407 T P S T + +VY F S T S + ST Sbjct: 1281 STHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTH 1340 Query: 408 YEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEM 467 E ++P GL + + + E T F +S ++ Sbjct: 1341 TTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTAD--LGEESTTFPSSSGSTGTKL 1398 Query: 468 EVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPIN---SSQALTNKVQMTSPSSTGSPM 524 P S + S+ + SS E TT SP S ++ T SP +T SP Sbjct: 1399 S-PARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPA 1457 Query: 525 FKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELS-------GSSSTLEPIISSSAHHV 577 SS + + + + P S T T++LS S + E +S + Sbjct: 1458 TTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGS--- 1514 Query: 578 TTVNSTNCKKT----PPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATS 633 TT +S + T P D E P + + G V ++P S + T + Sbjct: 1515 TTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLV-------EASTPTHSSTGSLHTTLT 1567 Query: 634 PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAK 693 P SS+ G E SW + P TA Sbjct: 1568 PA----------SSTSAGLQEESTTFQSWPSSS---------------DTTPSPPGTTAA 1602 Query: 694 QTGIET-----PNKSGKTTLSASGTGFGDKFKPVI---GTWDCDTCLVQNKPEAIKCVAC 745 + T P+ + T SAS T G + T L + V Sbjct: 1603 PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE 1662 Query: 746 ETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVS 805 T P + T T + T S T + D P + V S Sbjct: 1663 PTTSP---ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEES 1719 Query: 806 NNAEDNKCVSCMSEKPGS--------------SVPASSSSTVPVSLPSGGSLGLEK--FK 849 + + + PGS S P S+ +T+ + SLG E F Sbjct: 1720 TTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFH 1779 Query: 850 KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSS 909 GS + L L N S A T S + S++ S++F+ SS Sbjct: 1780 SSPGSTETTL-LPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSS 1838 Query: 910 SSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKP 969 + P+ T++ + S S S P + S +G + + S P Sbjct: 1839 KDTMPAPPTTTSAFVELST-------TSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSP 1891 Query: 970 EEVKKDSKNDNFKFGLSSGL--------SNPVSLTPFQFGVSNLGQEEKKEELPKSSSAG 1021 + + +SGL S+P S F S+ +E SS Sbjct: 1892 VAT---ATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSST- 1947 Query: 1022 FSFGTGVINSTPAPANTIV---TSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPAT 1078 T I+S P+ + +V TS + S + T +S + S A AT Sbjct: 1948 ----THTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDAT 2003 Query: 1079 KGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNS 1138 G + + + SV +LG E P++S S+ E P S Sbjct: 2004 ------GTIVLPARSTTSV-LLG---ESTTSPISSGSM---------ETTALP-----GS 2039 Query: 1139 EQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSS 1198 T + +TF S P+ S PA T + ++ STT+ ++P S+ Sbjct: 2040 TTTPGLSEKSTTFHSSPRSPATTLS--PASTTSSGVSEESTTSH---SRP------GSTH 2088 Query: 1199 SSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDS 1258 +++ P ++ G+ ST+S + P +T + P S++ G + ES+TS S S D+ Sbjct: 2089 TTAFPDSTTTPGLSRHSTTSHSSPGST---DTTLLPASTTTSGPSQESTTSHSSPGSTDT 2145 Query: 1259 KLATTSST----GTAVTPFVFGPGAS-----SNNTTTSGFGFGATTTSSSAGS-----SF 1304 L+ S+T G T F PG++ ++TT+SG +T SS GS S Sbjct: 2146 ALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSP 2205 Query: 1305 VFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSI---SSSTALFPTGSQPA--- 1358 T P S AF + T + P+PP + S+T GS P Sbjct: 2206 ASSTSPGLQGESTAFQTHPASTH------TTPSPPSTATAPVEESTTYHRSPGSTPTTHF 2259 Query: 1359 PPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFG 1418 P + T S + +F P SGTTP+S+ + G + + + + + T Sbjct: 2260 PASSTTSGHSEKSTIFHSSPD----ASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP 2315 Query: 1419 ANSSTPAASAQPSGSGGFPFNQ----SPAAFT---VGSNGKNVFSSSGTSFS 1463 +++TP S + P + SPA+ T VG S G++ S Sbjct: 2316 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHS 2367 Score = 94.4 bits (233), Expect = 7e-19 Identities = 340/1570 (21%), Positives = 534/1570 (34%), Gaps = 285/1570 (18%) Query: 69 STDTSEVPRWPENK---EDHLVYADEESSNITDGRITPEPAVSNTEEPSTT------STA 119 ST+T+ PR P E+ + +S T T + S E ST ST Sbjct: 2393 STETTVFPRTPTTSVRGEEPTTFHSRPASTHTT-LFTEDSTTSGLTEESTAFPGSPASTQ 2451 Query: 120 SNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDD 179 + P LT L F P+ T+ + P S+ LV E S Sbjct: 2452 TGLPATLTTADLGEESTTF-----PSSSGSTGTTLS-PARSTTSGLVGESTPSRLSPSST 2505 Query: 180 NISTTSGFSSRAS--DKDITVSKNTSLPPLW-SPEAERSHSLSQHTATSSKKP-AFNLSA 235 +T G + S +K T + P SP S +S+ ++TS +P + + +A Sbjct: 2506 ETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTA 2565 Query: 236 F--GTLSPSLGNSSILKTSQLG--DSPFYPGKTTYGGAAAAVRQSKLRNTPYQAP--VRR 289 F T +P L S S G D+ P TT G S+ T + +P Sbjct: 2566 FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGP------SQESTTSHSSPGSTDT 2619 Query: 290 QMKAKQLSAQSYGVTSST-------ARRILQSLEKMSSPLADAK-RIPSIVSSPLNSPLD 341 + +A S+G S+T L SS + +A R+ S SP + Sbjct: 2620 ALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSP 2679 Query: 342 RSGIDITDFQAKREKVDSQYPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRID 401 S T + E Q P TP P S AT P E ++ Sbjct: 2680 ASS---TSPGLQGESTTFQTHPASTHTTPSPPSTAT----------APVEESTTYHRSPG 2726 Query: 402 NKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKP 461 + +T + + T + E+ S P+ S + S G G + Sbjct: 2727 STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES---------TTSR 2777 Query: 462 LEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTG 521 + E+ LP + S T +SSP T++ SP + + + TS S G Sbjct: 2778 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 2837 Query: 522 SPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVN 581 ST + V P S+ T LS S+T+ S Sbjct: 2838 ------------STHSTVSPAST----------TTPGLSEESTTVYSSSPGSTETTVFPR 2875 Query: 582 STNCKKTPPEDCEGPFRPAE----ILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVY 637 ST E RPA + E S L A P P +T + Sbjct: 2876 STTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFP------GSPASTQTGL- 2928 Query: 638 TRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIA-CQAAKLSPRDTAKQTG 696 PA + +++ +G + SS T L + T + + ++LSP T T Sbjct: 2929 --PA--TLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTT- 2983 Query: 697 IETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKR 756 P +LS T F + T T E + +PG+ Sbjct: 2984 --LPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEE---SSTSHSQPGSTHTT 3038 Query: 757 AL-TLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE-----D 810 A T S ++ TAS SS T TL G +G + + E D Sbjct: 3039 AFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPD 3098 Query: 811 NKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTK 870 + S + E + ++ S ++ S S GL++ SW + +D+T Sbjct: 3099 DTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSW-------PSSSDTTP 3151 Query: 871 CLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQG 930 +A P S SS+ + ++SS G S S+ + +TG F + Sbjct: 3152 SPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRS 3211 Query: 931 GFKIGV--------------------SSDSGSINPMSEGFKFS--------KPIGDFKFG 962 + V S+ + ++ S F S P G Sbjct: 3212 ATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSG 3271 Query: 963 VSSESKPEEVKKDSKNDNFKFGL--------------SSGLSNPVSLTPFQFGVSNLGQE 1008 VS ES + S + G SS S +L+P S+LG E Sbjct: 3272 VSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPE 3331 Query: 1009 E----------KKEELPKSSSAG--FSFGTGVINSTPAPANTI-----VTSENKSSFNLG 1051 + LP +++A T V +ST +P T+ T + +S+ Sbjct: 3332 STTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQS 3391 Query: 1052 TIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLP----SASVFVLGRTEEK- 1106 +K + AP T+ + E+ T G P+S P SAS LGR+EE Sbjct: 3392 WPNSKDTTPAP---PTTTSAFVELSTTSHG------SPSSTPTTHFSASSTTLGRSEEST 3442 Query: 1107 --QQEPV-----------TSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDE--------- 1144 PV T++ LV + P F S+ T Sbjct: 3443 TVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHS 3502 Query: 1145 ------NSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSS 1198 +S+ ST S + +P+ S + AT F +STT+ + +++ Sbjct: 3503 STTHTISSAPSTTSALVEEPTSYHSSPGSTATTHF-PDSSTTSGRSEESTASHSSQDATG 3561 Query: 1199 SSSTPATSAGGGIFGSSTSS---------SNPPVATFVFGQSS----------------N 1233 + PA S + G ST+S + P +T G S + Sbjct: 3562 TIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLS 3621 Query: 1234 PVSSSAFGNTAESSTSQSLLFSQD-------------SKLATTS-----STGTAVTPFVF 1275 P S+++ G + ES+TS S S S+ +TTS ST T + P Sbjct: 3622 PASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAST 3681 Query: 1276 GPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQ 1335 SS +TTS G+T T+ S GS+ G + + + G+ T F S +S Sbjct: 3682 TTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSS- 3740 Query: 1336 PNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGT----TPNS 1391 G + +ST + S +P T + +SS+ P + G+ + + T +P S Sbjct: 3741 ------GIVEASTRVH--SSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPS 3792 Query: 1392 SSAFQFGSSTTNFNFTNNSPSGVF-----TFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446 ++ STT ++P+ F T G + + + P SG P S A T Sbjct: 3793 TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTP---SSAHST 3849 Query: 1447 VGSNGKNVFS 1456 G++ S Sbjct: 3850 TSGRGESTTS 3859 Score = 91.3 bits (225), Expect = 6e-18 Identities = 307/1469 (20%), Positives = 511/1469 (34%), Gaps = 211/1469 (14%) Query: 80 ENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFS 139 E+ L + E++ + TP S +E+ +T T+ PD P+ S + Sbjct: 2968 ESTPSRLSPSSTETTTLPGSPTTP----SLSEKSTTFYTSPRSPDATLSPATTTS--SGV 3021 Query: 140 MLESPALHCQPSTS--SAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSG----------- 186 ES H QP ++ +AFP ++ L +E S S + + G Sbjct: 3022 SEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQS 3081 Query: 187 --FSSRASDKDITVSKNTSLPPLWSPEAERSHSL--SQHTATSSKKPAFNLSAFGTLSPS 242 F S D + T+ + ++ + +HS S HT + PA + SA G S Sbjct: 3082 TTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT---PASSTSA-GLQEES 3137 Query: 243 LGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYG 302 S +S SP PG T + S+ +TP + Sbjct: 3138 TTFQSWPSSSDTTPSP--PGTTAAPVEVSTTYHSRPSSTP---------------TTHFS 3180 Query: 303 VTSSTARRILQSLEKMSSPLADAKRI-------PSIVSSPLNSPLDRSGIDITDFQAKRE 355 +S+T R +S SSP A + +V P SP+ + T Sbjct: 3181 ASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTT 3240 Query: 356 KVDSQYPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMT-P 414 +P+ S T S S S E ++ R + +T + + T P Sbjct: 3241 TAGLSEKSTTFYSSPR--SPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP 3298 Query: 415 GQNREQRES-------------GFSYPNFSLPAANGLSSGVGGGGGKMRRERTR----FV 457 G ++E S G + + P + SG G + + T Sbjct: 3299 GVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLE 3358 Query: 458 ASKPLEEE--EMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMT 515 AS P+ + P S S ++ + + TT +P S+ + Sbjct: 3359 ASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHG 3418 Query: 516 SPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAH 575 SPSST + F SS + +E + SS PVA S + ST ++ S Sbjct: 3419 SPSSTPTTHFSASSTTLGRSEESTTVHSS-------PVATATTPSPARSTTSGLVEESTT 3471 Query: 576 HVTTVNSTNCKKTPPEDC-EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSP 634 + ++ ST P D G + + I +P S ++ + ++ Sbjct: 3472 YHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGS 3531 Query: 635 VVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQ 694 T SS +S G E A S Q T + + + SP + Sbjct: 3532 TATTHFPDSSTTS---GRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSM 3588 Query: 695 TGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCV 754 P + LS T F + P + P T + Sbjct: 3589 ETTALPGSTTTPGLSEKSTTF------------------HSSPRS----------PATTL 3620 Query: 755 KRALTLTV-VSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKC 813 A T + VSE + T S S +T T F D P S + S + D Sbjct: 3621 SPASTTSSGVSEESTT----SHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL 3676 Query: 814 VSCMSEKPGSSVPA----SSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869 + + GSS + SSS + +L G + L S+ E + ST Sbjct: 3677 LPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTAL--------SFGQESTTFHSSPGST 3728 Query: 870 KCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQ 929 F S++SS +S+ V SS+ P TL+ + G Q Sbjct: 3729 HTTL--------------FPDSTTSSGIVEAST---RVHSSTGSPRTTLSPASSTSPGLQ 3771 Query: 930 G---GFKIGVSSD-------SGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979 G F+ +S S + P+ E + + G S+ + + Sbjct: 3772 GESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPG------STPTTHFPASSTTSGH 3825 Query: 980 NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039 + K + + TP + G+ E S+++ S G+ I + P T Sbjct: 3826 SEKSTIFHSSPDASGTTPSSAHSTTSGRGE-------STTSRISPGSTEITTLPGSTTTP 3878 Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKG--GFSFGNVEPASLPSASV 1097 SE ++F + + + +++P + TS EE ++ G + V PAS + Sbjct: 3879 GLSEASTTF-YSSPRSPTTTLSPASM-TSLGVGEESTTSRSQPGSTHSTVSPASTTTP-- 3934 Query: 1098 FVLGRTEEK----QQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSF 1153 G +EE P ++ + VF + + +P T ++ + + Sbjct: 3935 ---GLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTS 3991 Query: 1154 SMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFG 1213 +T+ S PA A T TTAD G F + S+ + +PA S G+ G Sbjct: 3992 GLTEESTAFPGSPASTQTGLPA-TLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVG 4050 Query: 1214 SSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKL--ATTSSTGTA-- 1269 ST S P +T +P + S + +S+T + S D+ L ATT+S+G + Sbjct: 4051 ESTPSRLSPSSTETTTLPGSPTTPSL---SEKSTTFYTSPRSPDATLSPATTTSSGVSEE 4107 Query: 1270 -----VTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQT 1324 P A ++TTTSG TT+ SS GS+ P + +AS Q+ Sbjct: 4108 SSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEA-TLSPGSTTASSL--GQQS 4164 Query: 1325 PTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAF- 1383 TF S G ++ +I+S T + + + T + + G Q + F Sbjct: 4165 TTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQ 4224 Query: 1384 ----GSGTTPN--SSSAFQFGSSTTNFNFTNNSPSGVF-----TFGANSSTPAASAQPSG 1432 S TTP+ S++A STT + +++P+ F T G + + + P Sbjct: 4225 SWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGA 4284 Query: 1433 SGGFPF-NQSPAAFTVGSNGKNVFSSSGT 1460 +G F +S + VG + SS T Sbjct: 4285 TGTALFPTRSATSVLVGEPTTSPISSGST 4313 Score = 90.5 bits (223), Expect = 1e-17 Identities = 313/1496 (20%), Positives = 500/1496 (33%), Gaps = 191/1496 (12%) Query: 69 STDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTR 128 S D P ++ D S I+ G + +T +P + ++ + Sbjct: 586 SPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRS 645 Query: 129 PSLHRSHLNFSML------ESPALHCQPSTS--SAFPIGSSGFSLVKEIKDSTSQHDDDN 180 P +HL SM ES H +P ++ +AFP ++ L +E ST+ H Sbjct: 646 PDT--THLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQE---STASH---- 696 Query: 181 ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS 240 S D T+S ++ PE HS T T+ N +A G L Sbjct: 697 --------SSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPD--NTTASGLLE 746 Query: 241 PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS 300 S+ S ++ SP G TT G + AP + S S Sbjct: 747 ASMPVHSSTRSPHTTLSP--AGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTS 804 Query: 301 YGVTSS------TARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKR 354 +G SS +AR L + S+ + + P + G + T + Sbjct: 805 HGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSST 864 Query: 355 EKVDSQYPPVQRLMTPKPVSI----ATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEK 410 S P + +P S + + +F S T SG ++ ++ +TG Sbjct: 865 THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATG--- 921 Query: 411 NMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVP 470 LPA + S +G + P+ ME Sbjct: 922 ------------------TIVLPARSTTSVLLGES------------TTSPISSGSMETT 951 Query: 471 VLP-KISLPITSSSLPTFNFS--SPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKF 527 LP + P S TF+ S SP T S S +S + + + P ST + F Sbjct: 952 ALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPD 1011 Query: 528 SSPIVKSTEANVLPPSSIGFTFS--VPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNC 585 S+ + + SS G T + +P + T ST S S + ST Sbjct: 1012 STTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTA 1071 Query: 586 KKTPPEDCEGPFRPAEILKEGSVLDILKSPGF--ASPKIDSVAAQP-TATSPVVYTRPAI 642 E P D S G AS ++ S P T SP T P + Sbjct: 1072 LSFGQESTTFHSNPGS-THTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL 1130 Query: 643 SSFSSSGIGFGESL-KAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPN 701 S++ S S T ++ T ++ P + T Sbjct: 1131 QGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASST------TSG 1184 Query: 702 KSGKTTL-----SASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKR 756 S K+T+ ASGT G + T + I + T PG + Sbjct: 1185 HSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPG--LSE 1242 Query: 757 ALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSC 816 A T S + T T S +S T +LG G++ + VS + +S Sbjct: 1243 ASTTFYSSPRSPTTTLSPASMT----SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSE 1298 Query: 817 MSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACES 876 S SS S+ +TV + G E L + ++ + Sbjct: 1299 ESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEEST 1358 Query: 877 AKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPS-QTLTSTGNFKFGDQGGFKIG 935 A PG+ + + ++ ++ S F SS S+G ST + G+ ++ Sbjct: 1359 AFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLS 1418 Query: 936 VSS----------DSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGL 985 SS + S++ S F S D ++ + V ++S + + G Sbjct: 1419 PSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS-SGVSEESSTSHSQPGS 1477 Query: 986 SSGLSNPVSLTPFQFG----VSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVT 1041 + + P S T S+ Q + L S+ S G +P +T T Sbjct: 1478 THTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETT 1537 Query: 1042 SENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPA--TKGGFSFGNVEPASLPSASVFV 1099 + G +E + P T PA T G + S PS+S Sbjct: 1538 LLPDDTITSGLVEAST----PTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSS--- 1590 Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSF-------GNSEQTKDENSS----- 1147 + P T+ + V + P P F G SE++ +SS Sbjct: 1591 ----DTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATG 1646 Query: 1148 ------KSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSS 1201 +S S + +P+ + T A T TTA F S ++ Sbjct: 1647 TALFPTRSATSVLVGEPTTSPISSGSTETTALPGST-TTAGLSEKSTTFYSSPRSPDTTL 1705 Query: 1202 TPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLA 1261 +PA++ G+ ST+S + P +T ++ P S++ G + ES+ S S S D+ L+ Sbjct: 1706 SPASTTSSGVSEESTTSHSRPGSTHT---TAFPGSTTMPGVSQESTASHSSPGSTDTTLS 1762 Query: 1262 ----TTSSTGTAVTPFVFGPGASS-----NNTTTSGFGFGATTTSSSAGS---------- 1302 T SS G T F PG++ +NTT SG +T SS GS Sbjct: 1763 PGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGS 1822 Query: 1303 ------SFVFGTGPSAPSASPAFGANQTPTFGQ----SQGASQPNPPGFGSISSST---A 1349 S F + PS+ PA T F + S G+ P S SS+T + Sbjct: 1823 TTRQGESTTFQSWPSSKDTMPA-PPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRS 1881 Query: 1350 LFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNN 1409 T +P T S ++ G +A+ S +P S+ F S+T + Sbjct: 1882 EESTTVHSSPVATATTPSPARSTTSGLVEESTAYHS--SPGSTQTMHFPESSTASGRSEE 1939 Query: 1410 SPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFSGR 1465 S + +S+T S+ PS + + + GS F S T+ SGR Sbjct: 1940 SRT-----SHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTT-SGR 1989 Score = 87.8 bits (216), Expect = 7e-17 Identities = 317/1454 (21%), Positives = 499/1454 (34%), Gaps = 252/1454 (17%) Query: 113 PSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDS 172 PS++ T + P P + S H +PS++ +S +L + ++S Sbjct: 1587 PSSSDTTPSPPGTTAAP----------VEVSTTYHSRPSSTPTTHFSASSTTLGRS-EES 1635 Query: 173 TSQHDDDNISTTSGFSSRASDKDITVSKNTSLPPLWS--------PEAERSHSLSQHTAT 224 T+ H + T+ F +R++ + TS P+ S P + + LS+ + T Sbjct: 1636 TTVHSSPGATGTALFPTRSATSVLVGEPTTS--PISSGSTETTALPGSTTTAGLSEKSTT 1693 Query: 225 ---SSKKPAFNLSAFGTLSPSLGNSSILKTSQLGDS--PFYPGKTTYGGAAAAVRQSKLR 279 S + P LS T S + S S+ G + +PG TT G V Q Sbjct: 1694 FYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG----VSQESTA 1749 Query: 280 NTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLE--------------KMSSPLADA 325 + + +A S G S+T S E + S+P+ + Sbjct: 1750 SHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSS 1809 Query: 326 KRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVSIATNRSVYFKP 385 P SP S R G + T FQ+ D+ P T + + + + P Sbjct: 1810 TGSPHTTLSPAGSTT-RQG-ESTTFQSWPSSKDTMPAPP----TTTSAFVELSTTSHGSP 1863 Query: 386 SLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGG 445 S TP+ F ++ T G++ E S S P A + Sbjct: 1864 SSTPTTHFSASST--------------TLGRSEE------STTVHSSPVATATTPSPARS 1903 Query: 446 GGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSS 505 E + S P + M P+ S S + SS T SSP S+ Sbjct: 1904 TTSGLVEESTAYHSSPGSTQTMH---FPESSTASGRSEESRTSHSSTTHTISSPPSTTSA 1960 Query: 506 QALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSV--PVAKTAELSGSS 563 +SP ST + F SS +E + SS T ++ P T + Sbjct: 1961 LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGE 2020 Query: 564 STLEPIISSSAHHVTTVNSTNCKKTPPEDC---EGPFRPAEILKEGSVLDILKSPGFASP 620 ST PI S S ST + P PA L S S G + Sbjct: 2021 STTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTT----SSGVSEE 2076 Query: 621 KIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIA 680 S ++P +T + S ++ G+ + S DT LL T + Sbjct: 2077 STTS-HSRPGSTHTTAFP----DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG--- 2128 Query: 681 CQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAI 740 ++ S + +T G TT + G ++ + P + Sbjct: 2129 --PSQESTTSHSSPGSTDTALSPGSTTALSFGQ---------------ESTTFHSSPGST 2171 Query: 741 KCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECS 800 + + A T S + T S +S T + G G F+ S + Sbjct: 2172 HTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASST-SPGLQGESTAFQTHPASTHTT 2230 Query: 801 VCCVSNNAEDNKCVSCMSEKPGSS----VPASSSSTVPVSLPSGGSLGLEKF-KKPEGSW 855 S + + PGS+ PASS++ SG S F P+ S Sbjct: 2231 PSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTT-------SGHSEKSTIFHSSPDASG 2283 Query: 856 DCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPS 915 + A ST ES G T S+ + S SS P+ Sbjct: 2284 T-----TPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPT 2338 Query: 916 QTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975 TL+ G +G S + P S S P G+S ES Sbjct: 2339 TTLSPASMTSLG------VGEESTTSRSQPGSTHSTVS-PASTTTPGLSEESTTV----- 2386 Query: 976 SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035 + S G S ++ P S G+E +S PA Sbjct: 2387 -------YSSSPG-STETTVFPRTPTTSVRGEEPT-----------------TFHSRPAS 2421 Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095 +T + +E+ ++ L T E+ + +P + +T +PAT G E + PS+ Sbjct: 2422 THTTLFTEDSTTSGL-TEESTAFPGSPASTQTG------LPATLTTADLGE-ESTTFPSS 2473 Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNE-EPKCQPVFSFGNSEQTKDENSSKSTFSFS 1154 S G T ++TS + G+ + P + S T + +TF S Sbjct: 2474 S----GSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTS 2529 Query: 1155 MTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGS 1214 P S PA T + ++ S+T+ ++P S+ +++ P ++ G+ Sbjct: 2530 PRSPDATLS--PATTTSSGVSEESSTSH---SQP------GSTHTTAFPDSTTTPGLSRH 2578 Query: 1215 STSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSST----GTAV 1270 ST+S + P +T + P S++ G + ES+TS S S D+ L+ S+T G Sbjct: 2579 STTSHSSPGST---DTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQES 2635 Query: 1271 TPFVFGPGASS-----NNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTP 1325 T F PG++ ++TT+SG +T SS GS T A S SP T Sbjct: 2636 TTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRT--TLSPASSTSPGLQGEST- 2692 Query: 1326 TFGQSQGASQ---PNPPGFGSI-------------SSSTALFPTGS------------QP 1357 TF Q+ AS P+PP + S+ T FP S Sbjct: 2693 TF-QTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHS 2751 Query: 1358 APPTFGTVSSSSQPPVFGQQPSQSAF------------GSGTTPNSSSAFQFGSSTTNFN 1405 +P GT SS+ G+ S ++ GS TTP S A S+ Sbjct: 2752 SPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSP 2811 Query: 1406 FTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT---VGSNGKNVFSSS---- 1458 T SP+ + + G + + +QP G SPA+ T + V+SSS Sbjct: 2812 TTTLSPASMTSLGVGEESTTSRSQP---GSTHSTVSPASTTTPGLSEESTTVYSSSPGST 2868 Query: 1459 GTSFSGRKIKTAVR 1472 T+ R T+VR Sbjct: 2869 ETTVFPRSTTTSVR 2882 Score = 87.4 bits (215), Expect = 9e-17 Identities = 319/1497 (21%), Positives = 505/1497 (33%), Gaps = 242/1497 (16%) Query: 93 SSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPST 152 S+ T + EP ++ ST +T ++PD T RS ES A H Sbjct: 3510 SAPSTTSALVEEPTSYHSSPGSTATT--HFPDSSTTSG--RSE------ESTASHSSQDA 3559 Query: 153 SSAFPIGSSGFSLVKEIKDSTSQHDDDNISTT----SGFSSRASDKDITVSKNTSLPPLW 208 + + + + V + +TS ++ TT S + S+K T + P Sbjct: 3560 TGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATT 3619 Query: 209 -SPEAERSHSLSQHTATSSKKP-AFNLSAF--GTLSPSLGNSSILKTSQLG--DSPFYPG 262 SP + S +S+ + TS +P + + +AF T +P L S S G D+ P Sbjct: 3620 LSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 3679 Query: 263 KTTYGGAA----AAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLEKM 318 TT G++ + S +T + Q S + ST + Sbjct: 3680 STTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTS 3739 Query: 319 SSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVSIATN 378 S + + R+ S SP + S T + E Q P TP P S AT Sbjct: 3740 SGIVEASTRVHSSTGSPRTTLSPASS---TSPGLQGESTAFQTHPASTHTTPSPPSTAT- 3795 Query: 379 RSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGL 438 P E ++ + +T + + T + E+ S P+ S + Sbjct: 3796 ---------APVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSA 3846 Query: 439 SSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSS 498 S G G + + E+ LP + S T +SSP T++ Sbjct: 3847 HSTTSGRGES---------TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTT 3897 Query: 499 PSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAE 558 SP + + + TS S G ST + V P S+ T Sbjct: 3898 LSPASMTSLGVGEESTTSRSQPG------------STHSTVSPAST----------TTPG 3935 Query: 559 LSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPAE----ILKEGSVLDILKS 614 LS S+T+ S ST E RPA + E S L Sbjct: 3936 LSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTE 3995 Query: 615 PGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVT 674 A P P +T + PA + +++ +G + SS T L + T Sbjct: 3996 ESTAFP------GSPASTQTGL---PA--TLTTADLGEESTTFPSSSGSTGTKLSPARST 4044 Query: 675 DNKCIA-CQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLV 733 + + ++LSP T T P +LS T F + T T Sbjct: 4045 TSGLVGESTPSRLSPSSTETTT---LPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 4101 Query: 734 QNKPEAIKCVACETPKPGTCVKRAL-TLTVVSESAETMTASSSSCTVTTGTLGFGDKFKR 792 E + +PG+ A T S ++ T S SS T TL G Sbjct: 4102 SGVSEE---SSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTAS 4158 Query: 793 PIGSWECSVCCVSNNAE-----DNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEK 847 +G + + E D+ S + E + ++ S ++ S S GL++ Sbjct: 4159 SLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQE 4218 Query: 848 FKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGV 907 SW + +D+T +A P S SS+ + ++SS G Sbjct: 4219 ESTTFQSW-------PSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGR 4271 Query: 908 SSSSSGPSQTLTSTGNFKFGDQGGFKIGV--------------------SSDSGSINPMS 947 S S+ + +TG F + + V S+ + ++ S Sbjct: 4272 SEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKS 4331 Query: 948 EGFKFS--------KPIGDFKFGVSSESK--------------PEEVKKDSKNDNFKFGL 985 F S P GVS ES P + Sbjct: 4332 TTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASH 4391 Query: 986 SSGLSNPVSLTPFQFGVSNLGQEE----------KKEELPKSSSAG--FSFGTGVINSTP 1033 SS S +L+P S+LG E + LP +++A T V +ST Sbjct: 4392 SSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTG 4451 Query: 1034 APANTI-----VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVE 1088 +P T+ T + +S+ +K + AP T+ + E+ T G Sbjct: 4452 SPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAP---PTTTSAFVELSTTSHG------S 4502 Query: 1089 PASLP----SASVFVLGRTEEK---QQEPV-----------TSTSLVFGKKADNEEPKCQ 1130 P+S P SAS LGR+EE PV T++ LV + P Sbjct: 4503 PSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGST 4562 Query: 1131 PVFSFGNSEQTKDE---------------NSSKSTFSFSMTKPSEKESEQPAKATFAFGA 1175 F S T +S+ ST S + +P+ S + AT F Sbjct: 4563 QTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHF-P 4621 Query: 1176 QTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTS---SSNPPVATFVFGQSS 1232 +STT+ + +++ + PA S + G ST+ SS T + G ++ Sbjct: 4622 DSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTT 4681 Query: 1233 NP----------VSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSN 1282 P S S+ T S++S +L S++S +S TA TP S Sbjct: 4682 TPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTP-------SPA 4734 Query: 1283 NTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFG-ANQTPTFGQSQGASQPNPPGF 1341 +TTSG +T SS GS+ P +S A G + ++ T S + +PP Sbjct: 4735 RSTTSGLVEESTAYHSSPGSTQTM----HFPESSTASGRSEESRTSHSSTTHTISSPP-- 4788 Query: 1342 GSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGS-----GTTPNSSSAFQ 1396 S +S+ PT +P + T G+ +A S G TP + Sbjct: 4789 -STTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTT 4847 Query: 1397 FGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQP----SGSGGFPFNQSPAAFTVGS 1449 G + F + S T + ++TP SA+ S S SPA+ T S Sbjct: 4848 SGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSS 4904 Score = 82.8 bits (203), Expect = 2e-15 Identities = 305/1451 (21%), Positives = 492/1451 (33%), Gaps = 199/1451 (13%) Query: 78 WPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSH-- 135 +P + + + ++S IT ++ T P +T+TA T S RS Sbjct: 239 FPSHSATSVFVGEPKTSPITSA------SMETTALPGSTTTAGLSEKSTTFYSSPRSPDR 292 Query: 136 -LNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASDK 194 L+ + S + + +TS + P G + DST+ ST S S Sbjct: 293 TLSPARTTSSGVSEKSTTSHSRP----GPTHTIAFPDSTTMPGVSQESTAS--HSIPGST 346 Query: 195 DITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNSSILKTSQL 254 D T+S T+ P PE+ HS +T T+ L + S +L+ S Sbjct: 347 DTTLSPGTTTPSSLGPESTTFHSSPGYTKTTR------------LPDNTTTSGLLEASTP 394 Query: 255 GDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQS 314 S TT +++ + + T +Q+ +K S G TS Sbjct: 395 VHSSTGSPHTTLSPSSSTTHEGE--PTTFQS----WPSSKDTSPAPSGTTS--------- 439 Query: 315 LEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVS 374 A K + SSP ++P T E PV TP P Sbjct: 440 --------AFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPAR 491 Query: 375 IATN----------------RSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNR 418 AT+ ++++F S T SG + + ST + K+ TP Sbjct: 492 SATSGHVEESTAYHRSPGSTQTMHFPESSTTSGH---SEESATFHGSTTHTKSSTPSTTA 548 Query: 419 EQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLP 478 + + S + S G R E ++ S P + M VLP S P Sbjct: 549 ALAHTSYHSSLGSTETTHFRDSSTISG----RSEESKASHSSP---DAMATTVLPAGSTP 601 Query: 479 ------ITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIV 532 T S + + + + + S+ P S ++ T SP +T P SS + Sbjct: 602 SVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVS 661 Query: 533 KSTEANVLPPSSIGFTFSVPVAKT-----AELSGSSSTLEPIISSSAHHVTTVNSTNCKK 587 + + + P S T + P + T E + S S+ P ++ + TT +S + Sbjct: 662 EESTTSHSRPGST-HTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEY 720 Query: 588 TP----PEDCEGPFRPAEILKEG------SVLDILKSPGFASPKIDSVAAQPTATSPVVY 637 T P E P G V +SP S Q +T+ + Sbjct: 721 TTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSW 780 Query: 638 -----TRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTA 692 TRPA + +S+ + + S T + T SP T Sbjct: 781 PSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQ 840 Query: 693 KQTGIETPNKSGK---TTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749 E+ SG+ +T S S T I + T + +P + Sbjct: 841 TMHFPESDTTSGRGEESTTSHSST------THTISSAPSTTSALVEEPTSYH------SS 888 Query: 750 PG-TCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNA 808 PG T + S +E TAS SS TGT+ + + E + +S+ + Sbjct: 889 PGSTATTHFPDSSTTSGRSEESTASHSS-QDATGTIVLPARSTTSVLLGESTTSPISSGS 947 Query: 809 EDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADS 868 + + + PG S ST S P + L E +++ S Sbjct: 948 METTALPGSTTTPG----LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGS 1003 Query: 869 TKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGN----- 923 T A + T G T+S SS + ++ S+++SGPSQ T++ + Sbjct: 1004 THTTAFPDST--TTPGLSRHSTTSHSSPGSTDTTL-LPASTTTSGPSQESTTSHSSSGST 1060 Query: 924 ---FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDN 980 G G S + NP S P G+ S S Sbjct: 1061 DTALSPGSTTALSFGQESTTFHSNPGSTHTTLF-PDSTTSSGIVEASTRVHSSTGSPRTT 1119 Query: 981 FKFGLSSGLSNPVSLTPFQ---FGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPAN 1037 S+ T FQ P S + G +T PA+ Sbjct: 1120 LSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPAS 1179 Query: 1038 TIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLP---- 1093 + + ++ S + S + T+ + E +T S G+ E +LP Sbjct: 1180 STTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGE---STTSRISPGSTEITTLPGSTT 1236 Query: 1094 -------SASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDEN- 1145 S + + R+ P + TSL G+++ + S + T Sbjct: 1237 TPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL 1296 Query: 1146 SSKSTFSFSMTKPSEKESEQP-AKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPA 1204 S +ST +S ++ S + + P + T G + +T + A+ F +S++S T Sbjct: 1297 SEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEE 1356 Query: 1205 TSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTS 1264 ++A G S+ + + T G+ S SS+ + S ++S TTS Sbjct: 1357 STAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARS----------TTS 1406 Query: 1265 STGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSA--SPAFGAN 1322 TP P SS TTT G+ TT S + S F T P +P A SPA + Sbjct: 1407 GLVGESTPSRLSP--SSTETTTLP---GSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 1461 Query: 1323 QTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSA 1382 + S SQP S+ T FP + T S SQ P SQ + Sbjct: 1462 SGVSEESSTSHSQPG-------STHTTAFPDST--------TTSDLSQEPTTSHS-SQGS 1505 Query: 1383 FGSGTTPNSSSAFQFGSSTTNFNF------TNNSPSGVFTFG-ANSSTPAASAQPSGSGG 1435 + +P S++A G +T F+ T P T G +STP S+ +G Sbjct: 1506 TEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSS----TGS 1561 Query: 1436 FPFNQSPAAFT 1446 +PA+ T Sbjct: 1562 LHTTLTPASST 1572 Score = 78.6 bits (192), Expect = 4e-14 Identities = 326/1556 (20%), Positives = 520/1556 (33%), Gaps = 272/1556 (17%) Query: 94 SNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHR----SHLNFSMLESPALHC- 148 ++ T ++ E S++ ST +TA +PD T P L R SH + ++ L Sbjct: 3623 ASTTSSGVSEESTTSHSRPGSTHTTA--FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAS 3680 Query: 149 -------QPSTSSAFPIGSSGFSL-------VKEIKDSTSQHDDDNISTTSGFSSRASDK 194 Q ST+S GS+ +L + ++ST+ H + T+ F + Sbjct: 3681 TTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSS 3740 Query: 195 DITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS----PSLGNSSILK 250 I + SP S + S + AF T + PS + + + Sbjct: 3741 GIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEE 3800 Query: 251 TSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARR 310 ++ SP T + ++ S+ + +P + + G ST R Sbjct: 3801 STTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR 3860 Query: 311 I------LQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPV 364 I + +L ++ ++ + SSP + S +T E S+ P Sbjct: 3861 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 3920 Query: 365 QRLMTPKPVSIAT------NRSVYFK-PSLTPSGEF-RKTNQRIDNKCSTGY-------- 408 T P S T + +VY P T + F R T + + T + Sbjct: 3921 STHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTH 3980 Query: 409 -----EKNMTPGQNREQRESGFSYPNFSLPAANGLS----------------SGVGGGGG 447 E + T G E ++P GL S G G Sbjct: 3981 TTLFTEDSTTSGLTEEST----AFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT 4036 Query: 448 KMRRERTRFVA----SKP--LEEEEMEVPVLP-KISLPITSSSLPTFNFS--SPEITTSS 498 K+ R+ S P L E LP + P S TF S SP+ T S Sbjct: 4037 KLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSP 4096 Query: 499 PSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSV--PVAKT 556 + +S + + + P ST + F S+ ++ SS G T + P + T Sbjct: 4097 ATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTT 4156 Query: 557 AELSGSSSTLEPIISSSAHHVTTVNSTNC-------KKTPPEDCEGPFR----PAE---- 601 A G ST SS TT+ + TP G PA Sbjct: 4157 ASSLGQQSTT--FHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTST 4214 Query: 602 -ILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPA---ISSFSSSGIGFGESLK 657 + +E + S +P S A P S ++RP+ + FS+S G S + Sbjct: 4215 GLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEE 4274 Query: 658 A----GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGT 713 + S T L + + + SP + P + LS T Sbjct: 4275 STTVHSSPGATGTALFPTRSATSVLVG--EPTTSPISSGSTETTALPGSTTTAGLSEKST 4332 Query: 714 GFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRAL-TLTVVSESAETMTA 772 F + T + E +PG+ A + T + ++ TA Sbjct: 4333 TFYSSPRSPDTTLSPASTTSSGVSEES---TTSHSRPGSMHTTAFPSSTTMPGVSQESTA 4389 Query: 773 SSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE-----DNKCVSCMSEKPGSSVPA 827 S SS T TL G +G + + E DN S + E +S P Sbjct: 4390 SHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLE---ASTPV 4446 Query: 828 SSSSTVP-VSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886 SS+ P +L GS + SW N D+T A P T S F Sbjct: 4447 HSSTGSPHTTLSPAGSTTRQGESTTFQSWP-------NSKDTTP------APPTTTSAFV 4493 Query: 887 GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946 T+S S S+ ++ F SS++ G S+ T+ + S+ SG + Sbjct: 4494 ELSTTSHGSPSSTPTTH-FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEES 4552 Query: 947 SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006 + F S+ + + + + + +SS S +L + Sbjct: 4553 TTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSP 4612 Query: 1007 QEEKKEELPKSS--SAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFT 1064 P SS S T +S A ++ + + +S LG ++ +P + Sbjct: 4613 GSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLG-----ESTTSPIS 4667 Query: 1065 CKTSEAKKEEMPATKGGFSFGNV----EPASLP----SASVFVLGRTEEK---QQEPV-- 1111 + E T G S + P+S P SAS LGR+EE PV Sbjct: 4668 SGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVAT 4727 Query: 1112 ---------TSTSLVFGKKADNEEPKCQPVFSF-------GNSEQTKDENSSK------- 1148 T++ LV A + P F G SE+++ +SS Sbjct: 4728 ATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSP 4787 Query: 1149 -STFSFSMTKPSEKESEQPAKATFAFGAQTSTTA------------DQGAAKPVFSFLNN 1195 ST S + +P+ S + AT F ++T+ D P+ + Sbjct: 4788 PSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTT 4847 Query: 1196 S--------------------SSSSSTPATSAGGGIFGSS-------------TSSSNPP 1222 S +S+++TP SA I SS TSSS Sbjct: 4848 SGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISG 4907 Query: 1223 VATFVFGQSSN------PVSSSAFGNTAESSTSQSLLFSQDSKLA----TTSSTGTAVTP 1272 T ++ Q+ + P S++ G + ES+T S S ++ L+ TTSS T Sbjct: 4908 EPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTT 4967 Query: 1273 FVFGPGA-----SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327 PG+ S +TT G +TT SS GS + + AF + T + Sbjct: 4968 PHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGS-----------TETTAFSHSNTMSI 5016 Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGT 1387 Q P+ PGF + T L P T T + F S A G+ Sbjct: 5017 HSQQSTPFPDSPGF----THTVL--------PATLTTTDIGQESTAF--HSSSDATGTTP 5062 Query: 1388 TPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPA 1443 P S+A T F + + SP+ F A+SST + + + F+ SP+ Sbjct: 5063 LPARSTASDLVGEPTTF-YISPSPTYTTLFPASSSTSGLTEEST-----TFHTSPS 5112 Score = 77.4 bits (189), Expect = 9e-14 Identities = 311/1442 (21%), Positives = 494/1442 (34%), Gaps = 208/1442 (14%) Query: 113 PSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDS 172 PS++ T + P P + S H +PS++ +S +L + ++S Sbjct: 3144 PSSSDTTPSPPGTTAAP----------VEVSTTYHSRPSSTPTTHFSASSTTLGRS-EES 3192 Query: 173 TSQHDDDNISTTSGFSSRASDKDITVSKNTSLPPLWS--------PEAERSHSLSQHTAT 224 T+ H + T+ F +R++ + TS P+ S P + + LS+ + T Sbjct: 3193 TTVHSSPGATGTALFPTRSATSVLVGEPTTS--PISSGSTETTALPGSTTTAGLSEKSTT 3250 Query: 225 ---SSKKPAFNLSAFGTLSPSLGNSSILKTSQLGDS--PFYPGKTTYGGAAAAVRQSKLR 279 S + P LS T S + S S+ G + +PG TT G V Q Sbjct: 3251 FYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG----VSQESTA 3306 Query: 280 NTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLE--------------KMSSPLADA 325 + + +A S G S+T S E + S+P+ + Sbjct: 3307 SHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSS 3366 Query: 326 KRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVSIATNRSVYFKP 385 P SP S R G + T FQ+ D+ TP P T S + + Sbjct: 3367 TGSPHTTLSPAGSTT-RQG-ESTTFQSWPNSKDT---------TPAP---PTTTSAFVEL 3412 Query: 386 SLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGG 445 S T G T +T + + T E+ + S P + + S G Sbjct: 3413 STTSHGSPSSTP-------TTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSG- 3464 Query: 446 GGKMRRERTRFVASKPLEEEEMEVPVLPKIS----LPITSSSLPTFNFSSPEITTSSPSP 501 + E T + +S P + M P S TS S T SS TTS+ Sbjct: 3465 ---LVEESTTYHSS-PGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVE 3520 Query: 502 INSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSV--PVAKTAEL 559 +S +SP ST + F SS +E + SS T ++ P T + Sbjct: 3521 EPTSYH-------SSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSV 3573 Query: 560 SGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDC---EGPFRPAEILKEGSV----LDIL 612 ST PI S S ST + P PA L S + Sbjct: 3574 LLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEE 3633 Query: 613 KSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNK 672 + + P A P +T+ +R + +S SS G DT LL Sbjct: 3634 STTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG-------------STDTTLLPAS 3680 Query: 673 VTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCL 732 T + +++ S + +T G TT + G ++ Sbjct: 3681 TTTSG-----SSQESTTSHSSSGSTDTALSPGSTTALSFGQ---------------ESTT 3720 Query: 733 VQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKR 792 + P + + + A T S + T S +S T + G G F+ Sbjct: 3721 FHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASST-SPGLQGESTAFQT 3779 Query: 793 PIGSWECSVCCVSNNAEDNKCVSCMSEKPGSS----VPASSS-------STVPVSLP-SG 840 S + S + + PGS+ PASS+ ST+ S P + Sbjct: 3780 HPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 3839 Query: 841 GSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAAS 900 G+ G + + + L + PG F +S S + S Sbjct: 3840 GTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS 3899 Query: 901 --SSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGD 958 S GV S+ S++ + + G+S +S ++ S G S Sbjct: 3900 PASMTSLGVGEEST-TSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPG---STETTV 3955 Query: 959 FKFGVSSESKPEEV----KKDSKNDNFKF---GLSSGLSN-----PVSLTPFQFGV-SNL 1005 F ++ + EE + + F +SGL+ P S Q G+ + L Sbjct: 3956 FPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATL 4015 Query: 1006 GQEEKKEELPKSSSAGFSFGTGVINSTPAPANT--IVTSENKSSFNLGTIETKSASVAPF 1063 + EE S+ S GT + +PA + T +V S + + ET + +P Sbjct: 4016 TTADLGEESTTFPSSSGSTGTKL---SPARSTTSGLVGESTPSRLSPSSTETTTLPGSPT 4072 Query: 1064 TCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKAD 1123 T SE K T + PA+ S+ V T Q P ++ + F Sbjct: 4073 TPSLSE--KSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQ--PGSTHTTAFPDSTT 4128 Query: 1124 NEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKA-TFAFGAQTSTTAD 1182 +P S + T+ S ST + S+ + S P T T T+ Sbjct: 4129 TSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGL 4188 Query: 1183 QGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTS----------SSNPPVATFVFGQSS 1232 A+ P S S ++ TPA+S G+ ST+ + +PP T V + S Sbjct: 4189 VEASTPTHSS-TGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVS 4247 Query: 1233 NPVSS--SAFGNTAESSTSQSLLFSQDSKLATTS--STGTAVTPFVFGPGASSNNTTTSG 1288 S S+ T S++S +L S++S +S +TGTA+ P TTS Sbjct: 4248 TTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSP 4307 Query: 1289 FGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSST 1348 G+T T++ GS+ G + ++ TF S + + SS Sbjct: 4308 ISSGSTETTALPGSTTTAGL------------SEKSTTFYSSPRSPDTTLSPASTTSSGV 4355 Query: 1349 ALFPTGSQPAPPTFGTVS--SSSQPPVFGQQPSQSAFGSGTT-----PNSSSAFQFGSST 1401 + T S P + T + SS+ P Q+ + S G+T P S++A G + Sbjct: 4356 SEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPES 4415 Query: 1402 TNFNFTNNSPSGVFTFGANSSTPA-----ASAQPSGSGGFPFNQ-SPAAFTVGSNGKNVF 1455 T F ++SP T +T A AS S G P SPA T F Sbjct: 4416 TTF---HSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTF 4472 Query: 1456 SS 1457 S Sbjct: 4473 QS 4474 Score = 62.0 bits (149), Expect = 4e-09 Identities = 118/482 (24%), Positives = 179/482 (37%), Gaps = 93/482 (19%) Query: 984 GLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSE 1043 G + G S + L+ +E ++ + S+ +GFS TG +T NT S Sbjct: 123 GRAEGFSLGLPLSEQARAAGAREKERQETVINHSTFSGFSQITGSTVNTSIGGNTTSAST 182 Query: 1044 NKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRT 1103 SS T SV T T+ K +T G S + S P A+ L + Sbjct: 183 PSSSDPFTTFSDYGVSVTFITGSTA-TKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPS 241 Query: 1104 EEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKES 1163 ++TS+ G EPK P+ T S + + Sbjct: 242 H-------SATSVFVG------EPKTSPI-----------------------TSASMETT 265 Query: 1164 EQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPV 1223 P T A ++ STT F S + +PA + G+ ST+S + P Sbjct: 266 ALPGSTTTAGLSEKSTT---------FYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPG 316 Query: 1224 ATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLA----TTSSTGTAVTPFVFGPGA 1279 T + P S++ G + ES+ S S+ S D+ L+ T SS G T F PG Sbjct: 317 PTHTI---AFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGY 373 Query: 1280 SS-----NNTTTSGFGFGATTTSSSAGSSF----------------VFGTGPSAPSASPA 1318 + +NTTTSG +T SS GS F + PS+ SPA Sbjct: 374 TKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPA 433 Query: 1319 FGANQTPTFGQSQGA--SQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQ 1376 + T F + S P+ S+S+ + P V++++ PP Sbjct: 434 -PSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPP---- 488 Query: 1377 QPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNS-------PSGVF---TFGANSSTPAA 1426 P++SA SG S++ + ST +F +S S F T SSTP+ Sbjct: 489 -PARSA-TSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPST 546 Query: 1427 SA 1428 +A Sbjct: 547 TA 548 Score = 58.2 bits (139), Expect = 6e-08 Identities = 133/623 (21%), Positives = 234/623 (37%), Gaps = 61/623 (9%) Query: 877 AKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGV 936 A GT S F T+ SS S+ ++ F SS++ G S+ T + Sbjct: 433 APSGTTSAFVKLSTTYHSSPSSTPTTH-FSASSTTLGHSEESTPVHSSPVATATTPPPAR 491 Query: 937 SSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLT 996 S+ SG + + + F SS + + + + + SS S +L Sbjct: 492 SATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALA 551 Query: 997 PFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTP-APANTIVTSENKSSFNLGTIET 1055 + S+LG E S+ +G S + +S+P A A T++ + + S +G Sbjct: 552 HTSYH-SSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVG---- 606 Query: 1056 KSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS 1115 ++ +P + + E TK G S + S P R+ + P + TS Sbjct: 607 -DSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSP--------RSPDTTHLPASMTS 657 Query: 1116 LVFGKKA--DNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAF 1173 +++ + P +F S T S +ST S S P++ + + Sbjct: 658 SGVSEESTTSHSRPGSTHTTAFPGST-TMPGLSQESTASHSSPGPTDTTLSPGSTTASSL 716 Query: 1174 GAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSN 1233 G + +T + + +N+++S A+ S ++ +P +T G+S+ Sbjct: 717 GPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTT 776 Query: 1234 --------------PVSSSAF--GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGP 1277 P ++SAF +T + S+ + S +TTS T + P Sbjct: 777 FHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSP 836 Query: 1278 GASSN-----NTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSA----------SPAFGAN 1322 G++ + TTSG G +TT+ SS ++ + PS SA SP G+ Sbjct: 837 GSTQTMHFPESDTTSGRGEESTTSHSS--TTHTISSAPSTTSALVEEPTSYHSSP--GST 892 Query: 1323 QTPTFGQSQGASQPNPPGFGSISSSTALFPTGS--QPAPPTFGTV--SSSSQPPVFGQQP 1378 T F S S + S SS A TG+ PA T + S++ P G Sbjct: 893 ATTHFPDSSTTSGRSEESTASHSSQDA---TGTIVLPARSTTSVLLGESTTSPISSGSME 949 Query: 1379 SQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPF 1438 + + GS TTP S S+ T SP+ + G + + + ++P + F Sbjct: 950 TTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAF 1009 Query: 1439 NQSPAAFTVGSNGKNVFSSSGTS 1461 S + + SS G++ Sbjct: 1010 PDSTTTPGLSRHSTTSHSSPGST 1032 Score = 47.4 bits (111), Expect = 1e-04 Identities = 78/298 (26%), Positives = 127/298 (42%), Gaps = 27/298 (9%) Query: 1191 SFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFV-FGQSSNPVS-SSAFGNTAESST 1248 +F S + ST TS GG +ST SS+ P TF +G S ++ S+A + +SST Sbjct: 157 TFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSST 216 Query: 1249 SQSLLFSQDSKLATT--SSTGTAVTP-------FVFGPGAS---SNNTTTSGFGFGATTT 1296 + S++S ++ + +TGT + P FV P S S + T+ G+TTT Sbjct: 217 NSG--HSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALP-GSTTT 273 Query: 1297 SSSAGSSFVFGTGPSAP--SASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTG 1354 + + S F + P +P + SPA + + + S+P P + ST + P Sbjct: 274 AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTM-PGV 332 Query: 1355 SQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGV 1414 SQ + + S+ G S TT +SS + + TT N + SG+ Sbjct: 333 SQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGY---TKTTRLP-DNTTTSGL 388 Query: 1415 F--TFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVF-SSSGTSFSGRKIKT 1469 + +SST + S S P F + K+ + SGT+ + K+ T Sbjct: 389 LEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLST 446 Score = 39.3 bits (90), Expect = 0.028 Identities = 143/664 (21%), Positives = 237/664 (35%), Gaps = 113/664 (17%) Query: 94 SNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESP-ALHCQPST 152 SN T GR S T STT T S+ P + +++E P + H P + Sbjct: 4570 SNTTSGR----GEESTTSHSSTTHTISSAPSTTS-----------ALVEEPTSYHSSPGS 4614 Query: 153 SSA--FPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASDKDITVSKNTSLPPLWS- 209 ++ FP S+ +E ST+ H + + T +R++ + TS P+ S Sbjct: 4615 TATTHFPDSSTTSGRSEE---STASHSSQDATGTIVLPARSTTSVLLGESTTS--PISSG 4669 Query: 210 -------PEAERSHSLSQHTATSSKKPAFNLSA-FGTLSPSLGNSSILKTSQLGDSPFYP 261 P + + LS+ + T P+ + F S +LG S +++ + SP Sbjct: 4670 SMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSE--ESTTVHSSPVAT 4727 Query: 262 GKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSP 321 T + + + +P Q S+ + G + + + +SSP Sbjct: 4728 ATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSP 4787 Query: 322 LADAKRIPSIVSSPLNSPLDRSGIDITDFQAK-------REKVDSQYPPVQRLMTPKPVS 374 + ++V P + I T F E S P +TP P Sbjct: 4788 PSTTS---ALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAH 4844 Query: 375 ------IATNRSVYFKP-SLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNRE-------- 419 IA + + Y P S+ + T + K + Y + +P Q Sbjct: 4845 FTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSS 4904 Query: 420 ---QRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKIS 476 + S +S + A S+ G + +E T F SKP E P Sbjct: 4905 ISGEPTSLYSQAESTHTTAFPASTTTSG----LSQESTTF-HSKPGSTETTLSPG----- 4954 Query: 477 LPITSSSLP---TFNFSSPEITTSSPSPINSSQALTNKVQMT---SPSSTGSPMFKFSSP 530 IT+SS T S P S+ SP +++ ++ T SP ST + F S+ Sbjct: 4955 -SITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNT 5013 Query: 531 IVKSTEANVLPPSSIGFTFSV-PVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTP 589 + ++ + P S GFT +V P T G ST A H +S++ T Sbjct: 5014 MSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQEST--------AFH----SSSDATGTT 5061 Query: 590 PEDCEGPFRPAEILKEGSVLDILKSPGF-----ASPKIDSVAAQPTA--TSPVVYTRPAI 642 P ++++ E + I SP + AS + + T TSP +T + Sbjct: 5062 PLPARS--TASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSP-SFTSTIV 5118 Query: 643 SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702 S+ S + G + G W C+ +C LSP ++ +ETP K Sbjct: 5119 STESLETLAPG-LCQEGQIWNGKQCVCPQGYVGYQC-------LSPLESFP---VETPEK 5167 Query: 703 SGKT 706 T Sbjct: 5168 LNAT 5171 >gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 99.4 bits (246), Expect = 2e-20 Identities = 216/1057 (20%), Positives = 377/1057 (35%), Gaps = 116/1057 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 TSS + + E TT S ++ A T + T+ S+TGS M V + + Sbjct: 130 TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM-----TTVFTAGSET 184 Query: 540 LPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598 + PS+ G T +V A + + S++ E +S+AH TT ST +T G Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244 Query: 599 PAEI------------------LKEGSVLDILKSPGFASPKIDSVAAQPTATS------- 633 E S + GF + + ++PT S Sbjct: 245 TVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETT 304 Query: 634 ------PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLS 687 P SS ++ G S+ +T + ++ + ++ S Sbjct: 305 MASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETS 364 Query: 688 PRDT-------AKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPE 738 T A G ET S G + S TG + + TC ++ Sbjct: 365 TDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMT 424 Query: 739 AIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWE 798 A+ ET T +T+ S+S T ++ S T T T G K GS Sbjct: 425 AVSTTVFETTTAST-EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSET 483 Query: 799 CSVC-----------------CVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS---L 837 + S + VS SE S S ++TV + Sbjct: 484 TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543 Query: 838 PSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSS---- 892 + + GLE EGS E+ V T + E + T + G +T++ Sbjct: 544 TTVSTTGLETTTTSTEGS---EMTTVSTTGAETTTDSTEGSGT-TAASTAGSETTTVSTA 599 Query: 893 SSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKF---GDQGGFKIGVS---SDSGSINPM 946 S N+ AS++ S+S++G T ST + + +G VS S++ ++ Sbjct: 600 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659 Query: 947 SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006 + G VS+ V + ++ + VS T G Sbjct: 660 GSERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTT----GSETTT 714 Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066 + E+ +S G T + + SE S+ G+ T +++ + T Sbjct: 715 TSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTM 774 Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126 S E A+ G V AS +VF E + + ST+ Sbjct: 775 ASIMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAG 829 Query: 1127 PKCQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTAD 1182 + P + G+ + T E S +T S S T + ES + AT G++T+T + Sbjct: 830 SETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTAST 888 Query: 1183 QGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGN 1242 +G+ S + S +T A++ G I ST+ S A+ +++ + + Sbjct: 889 EGSETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELT 944 Query: 1243 TAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS 1302 T ++ S+++ S + TT +T + T G+ + +T+G TTT+S GS Sbjct: 945 TVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGS 1001 Query: 1303 --SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPP 1360 + V TG + S G T T + + G S +TA++ TGS+ Sbjct: 1002 ETTTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE---- 1052 Query: 1361 TFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGAN 1420 T T + S+ S++ S +++ GS TT + + + V+ G+ Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112 Query: 1421 SSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457 ++T + + + +++ A T GS VF++ Sbjct: 1113 TTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149 Score = 94.4 bits (233), Expect = 7e-19 Identities = 201/994 (20%), Positives = 377/994 (37%), Gaps = 100/994 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T++S F ++ T S P+ ++ + T P +T V + + Sbjct: 274 TTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET 333 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599 + S++G + T +GS +T I+ S T+ +ST +T EG Sbjct: 334 IRASTVGSETT-----TVSTTGSETTTASIMGSE----TSTDSTTGSETTTASTEGS-ET 383 Query: 600 AEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF-----SSSGIGFGE 654 EGS + + G + + ++ T T A+S+ ++S G Sbjct: 384 TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443 Query: 655 SLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-----SPRDTAKQTGIETPN--KSGKTT 707 ++ + S + T + T A K S TA TG+ET G T Sbjct: 444 TIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDT 503 Query: 708 LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767 +AS G G+ ++ + ET T T T +E + Sbjct: 504 TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLE--TTTTSTEGS 561 Query: 768 ETMTASSSSCTVTT-GTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 E T S++ TT T G G GS +V ++E+ + SE +S Sbjct: 562 EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA--DSENTTASTADSETTSASTT 619 Query: 827 ASSSSTVPVSLPSGGSLGLEKFKKPEGSW-DCELCLVQNKADSTKCLACESAKPGTKSGF 885 S ++T + + E + S D E +V + E ++ T S Sbjct: 620 GSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSA- 678 Query: 886 KGFDTSSSSSNSAASSSFKFGVSS---SSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGS 942 G +T+ S+ S ++ G + S++G T TST G +I +S +GS Sbjct: 679 TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTE--------GSEITTASITGS 730 Query: 943 --INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQF 1000 +EG + + + S+ + E S + + ++S + + ++ Sbjct: 731 ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSS-ETTMASIMGSETTMA---- 785 Query: 1001 GVSNLGQEEKKEELPKSSSAGF---SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS 1057 S +G E K S + T + ++T + T+ T+ ++ TI + Sbjct: 786 --STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE------TIPAST 837 Query: 1058 ASVAPFTCKTSEAKKEEMPATKGG-FSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSL 1116 A T ++E + +T+G + + E + +A+ T + T+T+ Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897 Query: 1117 VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQ 1176 G + + + + T E ++ ST T S + SE +T G++ Sbjct: 898 TEGSETTTASTEGSEITTVST---TGSETTTASTEGSETTTASTEGSELTTVSTT--GSE 952 Query: 1177 TSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVS 1236 T T + +G+ + + S +T A++AG ST+ S A+ + G + VS Sbjct: 953 TITVSAEGSETTTVTTMG----SETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVS 1007 Query: 1237 SSAFGNTAESST-SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATT 1295 S+ T S+T +++ + S + TT +T + T V+ G+ + T+T G TT Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG---SETT 1064 Query: 1296 TSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGS 1355 T S+ GS + A A+ T + G+ GS +T ++ TGS Sbjct: 1065 TVSTTGSE-----------TTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGS 1111 Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415 + T ++S++ S++ S T+ +++A GS T T + + V Sbjct: 1112 K-------TTTASTEG-------SEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVS 1157 Query: 1416 TFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGS 1449 T G+ ++T +A+ + + +++ A T GS Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAGS 1191 Score = 88.6 bits (218), Expect = 4e-17 Identities = 188/993 (18%), Positives = 361/993 (36%), Gaps = 105/993 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T S T + E +T S + ++ A T + T+ S+ GS S+ ++T ++ Sbjct: 349 TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598 + + + +E++ S+T+ E +S+ T+ ST+ +T EG Sbjct: 409 TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 462 Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658 + GS + G + + + T V+T I S +++ G A Sbjct: 463 TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 515 Query: 659 GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716 S+ + + + ++N ++ ++ + T TG+ET S G + S TG Sbjct: 516 VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 572 Query: 717 DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776 G+ ++ + E T T + + +ET TAS++S Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 630 Query: 777 CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836 TT + GS +V + ++E + SE+ +S S ++TV + Sbjct: 631 SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 679 Query: 837 LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896 G E EGS + + ++ E+ T+ + + S Sbjct: 680 -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732 Query: 897 SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956 + AS+ ++S+ G T ST G + SS++ + M + I Sbjct: 733 TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 788 Query: 957 GDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPK 1016 G VS+ S +N + ++S ++ + VS G E +P Sbjct: 789 GSETTKVSTASSKMTTVF---TENSETTIASTTASETTT------VSTAGSET----IPA 835 Query: 1017 SSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMP 1076 S++ T ST T ++E + T +++ + +T+ A E Sbjct: 836 STAGS---ETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSE 892 Query: 1077 ATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKK---ADNEEPKCQPVF 1133 T AS + + + T + T+T+ G + A E + V Sbjct: 893 TTTTSTEGSETTTASTEGSEITTVSTTGSE-----TTTASTEGSETTTASTEGSELTTVS 947 Query: 1134 SFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAF--GAQTSTTADQGAAKPVFS 1191 + G+ T S++T +M + S ++ T G++T+T + +G+ S Sbjct: 948 TTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVS 1007 Query: 1192 FLNN-----SSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246 + S++ + T TS G + T++ + A + G + S+ T S Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVS 1067 Query: 1247 STSQSLLFSQDSKL-----------ATTSSTGTAVTPFVFGPGA---------------- 1279 +T + + L TT+ST + T V+ G+ Sbjct: 1068 TTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127 Query: 1280 --SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPN 1337 SS TT S G TT ++ + T S + S A G+ T T + + + Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS 1187 Query: 1338 PPGFGSISSSTA--LFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAF 1395 G + ++STA T S T +S S+ S+++ S +++AF Sbjct: 1188 TAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAF 1247 Query: 1396 QFGSSTTNFNFTNNSPSGVFTFGANSSTPAASA 1428 GS TT + + P+ G+ ++T + +A Sbjct: 1248 IIGSETTIASTASLEPTATSLTGSETTTVSITA 1280 Score = 85.1 bits (209), Expect = 5e-16 Identities = 157/800 (19%), Positives = 285/800 (35%), Gaps = 65/800 (8%) Query: 691 TAKQTGIETP-NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749 TA G ET + +G T + S TG +G+ ++ ET Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146 Query: 750 PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809 T T T + +ET AS++ +TT + E + VS Sbjct: 147 VSTVGSE--TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTT--VSTAGS 202 Query: 810 DNKCVSCMSEKPGSSVPASSSSTVPVSLPSG----GSLGLEKFKKPEGSWDCELCLVQNK 865 + VS + ++ A S +T ++ S + G E GS E + Sbjct: 203 ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---ETTAASTE 259 Query: 866 ADSTKCLACESAKPGTKSGFKGFDTSSSSSNSA----ASSSFKFGVSSSSSGPSQTLTST 921 T E +K T S GF+T+++S+ + AS+ +S+ GP T ST Sbjct: 260 DSETNTAFTEDSKTTTAST-TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVST 318 Query: 922 GN------FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975 + F G + V S++ +++ + +G S+ Sbjct: 319 ASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTAST 378 Query: 976 SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035 ++ + VS T + ++ E + S T +T + Sbjct: 379 EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438 Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095 + +T + S T T+ + T SE K A G L + Sbjct: 439 EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT----AYTTGSETTTASNTGLETT 494 Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK-----DENSSKST 1150 +VF +G + T+ V ++ S SE T E ++ ST Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSE------MTTVSTEGSENTTVSTTGSETTTVST 548 Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210 T S + SE +T GA+T+T + +G S +T A++AG Sbjct: 549 TGLETTTTSTEGSEMTTVSTT--GAETTTDSTEG--------------SGTTAASTAGSE 592 Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV 1270 ST+ S A+ ++++ ++ + TA +++S++ S + TT ST + Sbjct: 593 TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652 Query: 1271 TPFVFGPGA--------SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGAN 1322 T V G+ S TT S G T ++ +G++ V TG S G+ Sbjct: 653 TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-GSE 711 Query: 1323 QTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380 T T + + + G + ++ST + T S T ++ S+ S+ Sbjct: 712 TTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771 Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440 + S ++ A GS TT + ++ + VFT + ++ + +A + + ++ Sbjct: 772 TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831 Query: 1441 SPAAFTVGSNGKNVFSSSGT 1460 + A T GS S+ G+ Sbjct: 832 TIPASTAGSETTTTTSTEGS 851 Score = 79.3 bits (194), Expect = 2e-14 Identities = 219/1063 (20%), Positives = 383/1063 (36%), Gaps = 157/1063 (14%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T S T + + E TT+ + T + T+ S+ GS + S+ ++T A+ Sbjct: 399 TGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTAST 458 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSST------LEPIISSSAHHVTTVNSTNCKKTPPEDC 593 + T + KTA +GS +T LE + TT ST +T Sbjct: 459 EGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSA 518 Query: 594 EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSP-------VVYTRPAISSFS 646 G + EGS + + G + + + + T TS V T ++ S Sbjct: 519 TGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDS 577 Query: 647 SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706 + G G + AGS +T + ++N + ++ + +A TG ET S + Sbjct: 578 TEGSGTTAASTAGS----ETTTVSTADSENTTASTADSETT---SASTTGSETTTASTTS 630 Query: 707 TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766 + + + + G + + T D +T +V T +R +T T E Sbjct: 631 SETTTASTEGSE-TTTVSTTDSETTMVST----------------TGSERTITST---EG 670 Query: 767 AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSN-----NAEDNKCVSCM---S 818 +ET T S++ T T G G GS V + + E ++ + S Sbjct: 671 SETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGS 730 Query: 819 EKPGSSVPASSSSTVPVS---LPSGGSLGLEKFKKPEGSWDCELCLVQ-NKADSTKCLAC 874 E +S S ++T S + G E S + + + ++ + Sbjct: 731 ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGS 790 Query: 875 ESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSG----PSQTLTSTGNFKFGDQG 930 E+ K T S + +S + AS++ + S++G P+ T S +G Sbjct: 791 ETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEG 850 Query: 931 GFKIGVS---SDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSS 987 S S++ + + S + IG S+E ++ Sbjct: 851 SETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG 910 Query: 988 GLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVT--SENK 1045 VS T G + E +S+ G T +++T + T+ SE Sbjct: 911 SEITTVSTT----GSETTTASTEGSETTTASTEGSELTT--VSTTGSETITVSAEGSETT 964 Query: 1046 SSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGR--- 1102 + +G+ T +++ T S A E A+ G V + +V G Sbjct: 965 TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024 Query: 1103 ---TEEKQQEPVTS----TSLVFGKKADN-----EEPKCQPVFSFGNSEQTKD----ENS 1146 TE + VT+ T+ V+ ++ E + V + G+ T E + Sbjct: 1025 ITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084 Query: 1147 SKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPAT- 1205 + ST T S SE + G++T+T + +G+ S ++ ++++ST + Sbjct: 1085 TVSTSGSGTTTASTAGSE--TTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSE 1142 Query: 1206 ----------SAGGGIFGS--STSSSNPPVATFVFGQSSNPVSSSAFGN-TAESSTSQSL 1252 + GS +TSS+ AT + S ++S G+ T +ST+ S Sbjct: 1143 MTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS- 1201 Query: 1253 LFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS----SFVFG- 1307 TT+ST + T G+ +N T+G T+T SSAGS +F+ G Sbjct: 1202 -------ETTTASTAGSETTTASTSGSETNTACTTG---SETSTPSSAGSETNTAFIIGS 1251 Query: 1308 ------TGPSAPSASPAFGANQTPTFGQSQGAS---------------------QP--NP 1338 T P+A+ G+ T + GA+ QP N Sbjct: 1252 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1311 Query: 1339 PGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFG 1398 P G+ ++ T L + S P +S++ V G + S G+ T SS+ G Sbjct: 1312 PMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHG 1371 Query: 1399 SSTTNFNFTNNSPS-----GVFTFGAN----SSTPAASAQPSG 1432 TT + + S G + G N S TP +PSG Sbjct: 1372 VRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPSG 1414 Score = 79.0 bits (193), Expect = 3e-14 Identities = 193/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%) Query: 478 PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537 P S+ T + + E TT ++ A T + T+PS TGS S + T Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 68 Query: 538 NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582 + + + + TA ++GS +T+ E + S+ TT NS Sbjct: 69 STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS 128 Query: 583 TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642 T +T G E + + + S + DS + T + T Sbjct: 129 TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180 Query: 643 SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702 S + + G S+ +T + ++ + ++ + T + Sbjct: 181 GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 240 Query: 703 SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758 +TT+S +G+ T D +T +K ET T + + Sbjct: 241 GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295 Query: 759 TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810 T+ SE+ ET S++S VTT + + +GS VS + Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 352 Query: 811 NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869 S M SE S S ++T + E + S + DS Sbjct: 353 TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412 Query: 870 KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923 C T F+T+++S+ A++S + +S+ + T+T+ G+ Sbjct: 413 TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 472 Query: 924 FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979 K G + +S++G ++ + + G VS+ ++ Sbjct: 473 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532 Query: 980 NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039 N + + VS T G+ + E+ S+ G T +ST T Sbjct: 533 NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 585 Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099 ++ + + T ++++ + + +T+ A T + AS + Sbjct: 586 ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 645 Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156 + T+ + + ST+ E + V + G+ E S +T S + T Sbjct: 646 VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 703 Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208 K S SE +T G++T+T + +G+ S + S +T A++ G Sbjct: 704 KVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 759 Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265 +ST+SS +A+ + S ++S+ T + ST+ S +F+++S+ S+ Sbjct: 760 SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817 Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317 T TA + + A S TTT+ TTT+S+ GS + T S + + Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877 Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375 G+ T + + + G + ++ST + T S T + S+ Sbjct: 878 TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937 Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435 + S+ S T + + GS TT + + T G+ ++T + + + + Sbjct: 938 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 997 Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460 +++ + GS V S++GT Sbjct: 998 IEGSETTTVSSTGSETTTV-STTGT 1021 Score = 57.8 bits (138), Expect = 8e-08 Identities = 166/870 (19%), Positives = 303/870 (34%), Gaps = 96/870 (11%) Query: 476 SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535 S T S T + +S E TT+S ++ T + T S+TGS S+ ++T Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674 Query: 536 -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586 E V S T S+ ++T ++S GS +T S+ +TT + T Sbjct: 675 TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---TTSTEGSEITTASITG-S 730 Query: 587 KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646 +T EG EGS + G ++ A T++ + + + Sbjct: 731 ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 784 Query: 647 SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706 +S IG + + +S + T +N ++ + A++ + TA I +T Sbjct: 785 ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 842 Query: 707 TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766 T + S G G+ ++ + ET T + + T T +E Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 900 Query: 767 AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 +ET TAS+ +TT + + S + S + ++V Sbjct: 901 SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 947 Query: 827 ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886 + S T+ VS EGS + + ++ + E+ T Sbjct: 948 TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993 Query: 887 GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946 + S + SS+ + S++G T+TST G + S++ ++ Sbjct: 994 TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAVYTT 1049 Query: 947 SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006 + G VS+ + + S + S + + Sbjct: 1050 GSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYIT 1109 Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTI-ETKSASVAPFTC 1065 + + S A +++T + T T+ ++ + T+ ET + S Sbjct: 1110 GSKTTTASTEGSEA------TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163 Query: 1066 KTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNE 1125 TS A E T + E + +AS T T+T+ G + Sbjct: 1164 TTSSAAGSEATTT-------STEGSETTTASTAGSETTTASTAGSETTTASTAGSETT-- 1214 Query: 1126 EPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGA 1185 + + E ++ T + PS SE F G++T T A + Sbjct: 1215 -----------TASTSGSETNTACTTGSETSTPSSAGSE--TNTAFIIGSET-TIASTAS 1260 Query: 1186 AKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF----- 1240 +P + L + S ++T + +A G S+T SS V T S P++++ Sbjct: 1261 LEPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRT 1318 Query: 1241 -GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTS 1297 G +S+S ++ D + S T + G G S+ ++TTS G TT S Sbjct: 1319 TGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGS 1378 Query: 1298 SSAGSSFVF-GTGPSAPSASPAFGANQTPT 1326 + +S F TGP + + + TPT Sbjct: 1379 TREPTSSTFQETGPVSMGTN-TVSMSHTPT 1407 Score = 41.6 bits (96), Expect = 0.006 Identities = 50/197 (25%), Positives = 80/197 (40%), Gaps = 29/197 (14%) Query: 1277 PGASSNNTTTSGFGF---------GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327 P A SN TT S G TTT+S+AGS T PS + + Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET---TTPSPTGSQTTIVSISGSEI 65 Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ-SAFGSG 1386 + A N + S +T GS+ T G S ++ + G + + SA GS Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG--SETTTVSITGTETTMVSAMGSE 123 Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446 TT NS+++ S TT + + + V T G+ ++T + +++ AA T Sbjct: 124 TTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYTAD----------SETTAAST 169 Query: 1447 VGSNGKNVFSSSGTSFS 1463 GS VF++ + + Sbjct: 170 TGSEMTTVFTAGSETIT 186 >gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] Length = 1521 Score = 99.4 bits (246), Expect = 2e-20 Identities = 207/1055 (19%), Positives = 376/1055 (35%), Gaps = 112/1055 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 TSS + + E TT S ++ A T + T+ S+TGS M + + + + Sbjct: 130 TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM----TTVFTAGSETI 185 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599 P ++ T +V A + + S++ E +S+AH TT ST +T G Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245 Query: 600 AE------------------ILKEGSVLDILKSPGFASPKIDSVAAQPTATS-------- 633 E S + GF + + ++PT S Sbjct: 246 VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTM 305 Query: 634 -----PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-- 686 P SS ++ G S+ +T + ++ + ++ Sbjct: 306 ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365 Query: 687 -----SPRDTAKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEA 739 S TA G ET S G + S TG + + TC ++ A Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425 Query: 740 IKCVACETPKPGT------------------CVKRALTLTVVSESAETMTA-SSSSCTVT 780 + ET T + + T TV + +ET TA ++ S T T Sbjct: 426 VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485 Query: 781 TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS--- 836 G IGS S + VS SE S S ++TV + Sbjct: 486 ASNTGLETTTVFTIGS---DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSE 542 Query: 837 LPSGGSLGLE-KFKKPEGS-------WDCELCLVQNKADSTKCLACESAKPGTKSGFKGF 888 + + GLE EGS E + T + ++ T S Sbjct: 543 TTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSE 602 Query: 889 DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE 948 +T++S+++S +S+ G ++++ + + T+T + + G + S++ ++ Sbjct: 603 NTTASTADSETTSASTTGSETTTASTTSSETTTASTE-GSETTTVSTTDSETTMVSTTGS 661 Query: 949 GFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQE 1008 + G VS+ V + ++ + VS T G Sbjct: 662 ERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTT----GSETTTTS 716 Query: 1009 EKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTS 1068 + E+ +S G T + + SE S+ G+ T +++ + T S Sbjct: 717 TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776 Query: 1069 EAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPK 1128 E A+ G V AS +VF E + + ST+ + Sbjct: 777 IMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAGSE 831 Query: 1129 CQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTADQG 1184 P + G+ + T E S +T S S T + ES + AT G++T+T + +G Sbjct: 832 TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTASTEG 890 Query: 1185 AAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTA 1244 + S + S +T A++ G I ST+ S A+ +++ + + T Sbjct: 891 SETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTV 946 Query: 1245 ESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-- 1302 ++ S+++ S + TT +T + T G+ + +T+G TTT+S GS Sbjct: 947 STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGSET 1003 Query: 1303 SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF 1362 + V TG + S G T T + + G S +TA++ TGS+ T Sbjct: 1004 TTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE----TT 1054 Query: 1363 GTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS 1422 T + S+ S++ S +++ GS TT + + + V+ G+ ++ Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114 Query: 1423 TPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457 T + + + +++ A T GS VF++ Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149 Score = 95.1 bits (235), Expect = 4e-19 Identities = 206/1019 (20%), Positives = 385/1019 (37%), Gaps = 104/1019 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T++S F ++ T S P+ ++ + T P +T V + + Sbjct: 274 TTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET 333 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599 + S++G + T +GS +T I+ S T+ +ST +T EG Sbjct: 334 IRASTVGSETT-----TVSTTGSETTTASIMGSE----TSTDSTTGSETTTASTEGS-ET 383 Query: 600 AEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF-----SSSGIGFGE 654 EGS + + G + + ++ T T A+S+ ++S G Sbjct: 384 TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443 Query: 655 SLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-----SPRDTAKQTGIETPN--KSGKTT 707 ++ + S + T + T A K S TA TG+ET G T Sbjct: 444 TIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDT 503 Query: 708 LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767 +AS G G+ ++ + ET T T T +E + Sbjct: 504 TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLE--TTTTSTEGS 561 Query: 768 ETMTASSSSCTVTT-GTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 E T S++ TT T G G GS +V ++E+ + SE +S Sbjct: 562 EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA--DSENTTASTADSETTSASTT 619 Query: 827 ASSSSTVPVSLPSGGSLGLEKFKKPEGSW-DCELCLVQNKADSTKCLACESAKPGTKSGF 885 S ++T + + E + S D E +V + E ++ T S Sbjct: 620 GSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSA- 678 Query: 886 KGFDTSSSSSNSAASSSFKFGVSS---SSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGS 942 G +T+ S+ S ++ G + S++G T TST G +I +S +GS Sbjct: 679 TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTE--------GSEITTASITGS 730 Query: 943 --INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQF 1000 +EG + + + S+ + E S + + ++S + + ++ Sbjct: 731 ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSS-ETTMASIMGSETTMA---- 785 Query: 1001 GVSNLGQEEKKEELPKSSSAGF---SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS 1057 S +G E K S + T + ++T + T+ T+ ++ TI + Sbjct: 786 --STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE------TIPAST 837 Query: 1058 ASVAPFTCKTSEAKKEEMPATKGG-FSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSL 1116 A T ++E + +T+G + + E + +A+ T + T+T+ Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897 Query: 1117 VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQ 1176 G + + + + T E ++ ST T S + SE +T G++ Sbjct: 898 TEGSETTTASTEGSEITTVST---TGSETTTASTEGSETTTASTEGSELTTVSTT--GSE 952 Query: 1177 TSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVS 1236 T T + +G+ + + S +T A++AG ST+ S A+ + G + VS Sbjct: 953 TITVSAEGSETTTVTTMG----SETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVS 1007 Query: 1237 SSAFGNTAESST-SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATT 1295 S+ T S+T +++ + S + TT +T + T V+ G+ + T+T G TT Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG---SETT 1064 Query: 1296 TSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGS 1355 T S+ GS + A A+ T + G+ GS +T ++ TGS Sbjct: 1065 TVSTTGSE-----------TTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGS 1111 Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415 + T ++S++ S++ S T+ +++A GS T T + + V Sbjct: 1112 K-------TTTASTEG-------SEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVS 1157 Query: 1416 TFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSG----TSFSGRKIKTA 1470 T G+ ++T +A+ + + +++ A T GS ++ S SG + TA Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTA 1216 Score = 86.7 bits (213), Expect = 2e-16 Identities = 186/973 (19%), Positives = 359/973 (36%), Gaps = 75/973 (7%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T S T + E +T S + ++ A T + T+ S+ GS S+ ++T ++ Sbjct: 349 TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598 + + + +E++ S+T+ E +S+ T+ ST+ +T EG Sbjct: 409 TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 462 Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658 + GS + G + + + T V+T I S +++ G A Sbjct: 463 TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 515 Query: 659 GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716 S+ + + + ++N ++ ++ + T TG+ET S G + S TG Sbjct: 516 VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 572 Query: 717 DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776 G+ ++ + E T T + + +ET TAS++S Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 630 Query: 777 CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836 TT + GS +V + ++E + SE+ +S S ++TV + Sbjct: 631 SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 679 Query: 837 LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896 G E EGS + + ++ E+ T+ + + S Sbjct: 680 -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732 Query: 897 SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956 + AS+ ++S+ G T ST G + SS++ + M + I Sbjct: 733 TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 788 Query: 957 GDFKFGVSS-ESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELP 1015 G VS+ SK V ++ +S + + S G E Sbjct: 789 GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT--- 845 Query: 1016 KSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEM 1075 +S+ G T + + +SE ++ +G+ T +++ T TS E Sbjct: 846 -TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904 Query: 1076 PATKGGFSFGNVEPASLPSASVFVLGR------TEEKQQEPVTST-SLVFGKKADNEEPK 1128 A+ G V + + G TE + V++T S A+ E Sbjct: 905 TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964 Query: 1129 CQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATF--AFGAQTSTTADQGAA 1186 V + G+ T S++T + + S + ++ T + G++T+T + G Sbjct: 965 T--VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1022 Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246 + S + S +T T+AG T+ S + +++ ++ + TA + Sbjct: 1023 TTITS----TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078 Query: 1247 STSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSG-------FGFGATTTSSS 1299 + ++ S TT+ST + T V+ G+ + +T G TTT+S+ Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAST 1138 Query: 1300 AGSSF--VFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTA--LFPTGS 1355 GS VF T + S G+ T + A+ + G + ++STA T S Sbjct: 1139 TGSEMTTVFTTVSETTTVS-TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1197 Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415 T +S S+ S+++ S +++AF GS TT + + P+ Sbjct: 1198 TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATS 1257 Query: 1416 TFGANSSTPAASA 1428 G+ ++T + +A Sbjct: 1258 LTGSETTTVSITA 1270 Score = 85.1 bits (209), Expect = 5e-16 Identities = 157/800 (19%), Positives = 285/800 (35%), Gaps = 65/800 (8%) Query: 691 TAKQTGIETP-NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749 TA G ET + +G T + S TG +G+ ++ ET Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146 Query: 750 PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809 T T T + +ET AS++ +TT + E + VS Sbjct: 147 VSTVGSE--TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTT--VSTAGS 202 Query: 810 DNKCVSCMSEKPGSSVPASSSSTVPVSLPSG----GSLGLEKFKKPEGSWDCELCLVQNK 865 + VS + ++ A S +T ++ S + G E GS E + Sbjct: 203 ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---ETTAASTE 259 Query: 866 ADSTKCLACESAKPGTKSGFKGFDTSSSSSNSA----ASSSFKFGVSSSSSGPSQTLTST 921 T E +K T S GF+T+++S+ + AS+ +S+ GP T ST Sbjct: 260 DSETNTAFTEDSKTTTAST-TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVST 318 Query: 922 GN------FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975 + F G + V S++ +++ + +G S+ Sbjct: 319 ASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTAST 378 Query: 976 SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035 ++ + VS T + ++ E + S T +T + Sbjct: 379 EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438 Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095 + +T + S T T+ + T SE K A G L + Sbjct: 439 EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT----AYTTGSETTTASNTGLETT 494 Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK-----DENSSKST 1150 +VF +G + T+ V ++ S SE T E ++ ST Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSE------MTTVSTEGSENTTVSTTGSETTTVST 548 Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210 T S + SE +T GA+T+T + +G S +T A++AG Sbjct: 549 TGLETTTTSTEGSEMTTVSTT--GAETTTDSTEG--------------SGTTAASTAGSE 592 Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV 1270 ST+ S A+ ++++ ++ + TA +++S++ S + TT ST + Sbjct: 593 TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652 Query: 1271 TPFVFGPGA--------SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGAN 1322 T V G+ S TT S G T ++ +G++ V TG S G+ Sbjct: 653 TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-GSE 711 Query: 1323 QTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380 T T + + + G + ++ST + T S T ++ S+ S+ Sbjct: 712 TTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771 Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440 + S ++ A GS TT + ++ + VFT + ++ + +A + + ++ Sbjct: 772 TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831 Query: 1441 SPAAFTVGSNGKNVFSSSGT 1460 + A T GS S+ G+ Sbjct: 832 TIPASTAGSETTTTTSTEGS 851 Score = 79.0 bits (193), Expect = 3e-14 Identities = 193/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%) Query: 478 PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537 P S+ T + + E TT ++ A T + T+PS TGS S + T Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 68 Query: 538 NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582 + + + + TA ++GS +T+ E + S+ TT NS Sbjct: 69 STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS 128 Query: 583 TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642 T +T G E + + + S + DS + T + T Sbjct: 129 TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180 Query: 643 SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702 S + + G S+ +T + ++ + ++ + T + Sbjct: 181 GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 240 Query: 703 SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758 +TT+S +G+ T D +T +K ET T + + Sbjct: 241 GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295 Query: 759 TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810 T+ SE+ ET S++S VTT + + +GS VS + Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 352 Query: 811 NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869 S M SE S S ++T + E + S + DS Sbjct: 353 TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412 Query: 870 KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923 C T F+T+++S+ A++S + +S+ + T+T+ G+ Sbjct: 413 TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 472 Query: 924 FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979 K G + +S++G ++ + + G VS+ ++ Sbjct: 473 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532 Query: 980 NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039 N + + VS T G+ + E+ S+ G T +ST T Sbjct: 533 NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 585 Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099 ++ + + T ++++ + + +T+ A T + AS + Sbjct: 586 ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 645 Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156 + T+ + + ST+ E + V + G+ E S +T S + T Sbjct: 646 VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 703 Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208 K S SE +T G++T+T + +G+ S + S +T A++ G Sbjct: 704 KVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 759 Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265 +ST+SS +A+ + S ++S+ T + ST+ S +F+++S+ S+ Sbjct: 760 SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817 Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317 T TA + + A S TTT+ TTT+S+ GS + T S + + Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877 Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375 G+ T + + + G + ++ST + T S T + S+ Sbjct: 878 TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937 Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435 + S+ S T + + GS TT + + T G+ ++T + + + + Sbjct: 938 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 997 Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460 +++ + GS V S++GT Sbjct: 998 IEGSETTTVSSTGSETTTV-STTGT 1021 Score = 74.3 bits (181), Expect = 8e-13 Identities = 188/936 (20%), Positives = 323/936 (34%), Gaps = 102/936 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTE--- 536 T S + T + E TT S + ++ T ++ T+ S+ GS M S+ ++T Sbjct: 519 TGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST 578 Query: 537 --ANVLPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDC 593 + S+ G T +V A + + S++ E +S+ TT ST +T Sbjct: 579 EGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAST 638 Query: 594 EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSS----G 649 EG + S ++ + G + I S T T + +S+ S Sbjct: 639 EGS-ETTTVSTTDSETTMVSTTG-SERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696 Query: 650 IGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTT 707 I E+ K ++ T T+ I + S TA G ET S G T Sbjct: 697 ITGSETTKVSTTGSETT----TTSTEGSEITTASITGSETTTASTEGSETTTASTEGSET 752 Query: 708 LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767 SAS TG + ++ ++ + ET K T + T V +E++ Sbjct: 753 TSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT--VFTENS 810 Query: 768 ETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPA 827 ET AS+++ TT + + E + + +E + SE +S + Sbjct: 811 ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTES 870 Query: 828 SSSSTVPVSLPSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886 S ++T ++G E EGS E + T + E ++ T S Sbjct: 871 SETTTAT-------TIGSETTTASTEGS---ETTTTSTEGSETTTASTEGSEITTVS--- 917 Query: 887 GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS---SDSGSI 943 ++ S + AS+ ++S+ G T ST G I VS S++ ++ Sbjct: 918 ----TTGSETTTASTEGSETTTASTEGSELTTVST-------TGSETITVSAEGSETTTV 966 Query: 944 NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVS 1003 M + G VS+ ++ + + VS T + ++ Sbjct: 967 TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTIT 1026 Query: 1004 NLGQEEKKEELPKSSSAGFSFGTG---VINSTPAPANTIVTSENKSSFNLGTIETKSASV 1060 + E S + TG ST T V++ + T + ++ +V Sbjct: 1027 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTV 1086 Query: 1061 APFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS---LV 1117 + T+ A T + AS + + T + T+ S V Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146 Query: 1118 FGKKADNEEPKC----QPVFSFGNSEQTK-----DENSSKSTFSFSMTKPSEKESEQPAK 1168 F ++ S SE T E ++ ST T S SE Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTA 1206 Query: 1169 ATFAF--------GAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSN 1220 +T G++TST + G+ + + ++ +ST +S Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAST---------------ASL 1251 Query: 1221 PPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGAS 1280 P AT + G + VS +A G TA S+T S F T +T ++ P P + Sbjct: 1252 EPTATSLTGSETTTVSITASGATAASTTVSSTTF------VLTKATDVSIQPITNTPMSG 1305 Query: 1281 SNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPG 1340 + T G T +SS + + T +A P N + + GAS Sbjct: 1306 TRTT-----GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAH 1360 Query: 1341 FGSISSSTALFPTGS---QPAPPTFG--TVSSSSQP 1371 ++ + PT S + P + G TVS S P Sbjct: 1361 GVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTP 1396 Score = 54.7 bits (130), Expect = 7e-07 Identities = 165/869 (18%), Positives = 302/869 (34%), Gaps = 104/869 (11%) Query: 476 SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535 S T S T + +S E TT+S ++ T + T S+TGS S+ ++T Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674 Query: 536 -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586 E V S T S+ ++T ++S GS +T S+ +TT + T Sbjct: 675 TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---TTSTEGSEITTASITG-S 730 Query: 587 KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646 +T EG EGS + G ++ A T++ + + + Sbjct: 731 ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 784 Query: 647 SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706 +S IG + + +S + T +N ++ + A++ + TA I +T Sbjct: 785 ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 842 Query: 707 TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766 T + S G G+ ++ + ET T + + T T +E Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 900 Query: 767 AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 +ET TAS+ +TT + + S + S + ++V Sbjct: 901 SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 947 Query: 827 ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886 + S T+ VS EGS + + ++ + E+ T Sbjct: 948 TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993 Query: 887 GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946 + S + SS+ + S++G T+TST G + S++ ++ Sbjct: 994 TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAV--- 1046 Query: 947 SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006 + SE+ + G + ++ L S G Sbjct: 1047 --------------YTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066 ++++ + TG +T + + T+ + +S T T + + Sbjct: 1093 TTTASTAGSETTTV---YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149 Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126 SE T + G+ S + S TE + T+T+ G + Sbjct: 1150 VSE--------TTTVSTIGSEATTSSAAGSEATTTSTEGSE----TTTASTAGSETTTAS 1197 Query: 1127 PKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAA 1186 + S E ++ T + PS SE F G++T T A + Sbjct: 1198 TAGSETTTASTS---GSETNTACTTGSETSTPSSAGSE--TNTAFIIGSET-TIASTASL 1251 Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF------ 1240 +P + L + S ++T + +A G S+T SS V T S P++++ Sbjct: 1252 EPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1309 Query: 1241 GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTSS 1298 G +S+S ++ D + S T + G G S+ ++TTS G TT S+ Sbjct: 1310 GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369 Query: 1299 SAGSSFVF-GTGPSAPSASPAFGANQTPT 1326 +S F TGP + + + TPT Sbjct: 1370 REPTSSTFQETGPVSMGTN-TVSMSHTPT 1397 Score = 41.6 bits (96), Expect = 0.006 Identities = 50/197 (25%), Positives = 80/197 (40%), Gaps = 29/197 (14%) Query: 1277 PGASSNNTTTSGFGF---------GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327 P A SN TT S G TTT+S+AGS T PS + + Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET---TTPSPTGSQTTIVSISGSEI 65 Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ-SAFGSG 1386 + A N + S +T GS+ T G S ++ + G + + SA GS Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG--SETTTVSITGTETTMVSAMGSE 123 Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446 TT NS+++ S TT + + + V T G+ ++T + +++ AA T Sbjct: 124 TTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYTAD----------SETTAAST 169 Query: 1447 VGSNGKNVFSSSGTSFS 1463 GS VF++ + + Sbjct: 170 TGSEMTTVFTAGSETIT 186 >gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] Length = 1612 Score = 99.4 bits (246), Expect = 2e-20 Identities = 207/1055 (19%), Positives = 376/1055 (35%), Gaps = 112/1055 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 TSS + + E TT S ++ A T + T+ S+TGS M + + + + Sbjct: 130 TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM----TTVFTAGSETI 185 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599 P ++ T +V A + + S++ E +S+AH TT ST +T G Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245 Query: 600 AE------------------ILKEGSVLDILKSPGFASPKIDSVAAQPTATS-------- 633 E S + GF + + ++PT S Sbjct: 246 VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTM 305 Query: 634 -----PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-- 686 P SS ++ G S+ +T + ++ + ++ Sbjct: 306 ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365 Query: 687 -----SPRDTAKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEA 739 S TA G ET S G + S TG + + TC ++ A Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425 Query: 740 IKCVACETPKPGT------------------CVKRALTLTVVSESAETMTA-SSSSCTVT 780 + ET T + + T TV + +ET TA ++ S T T Sbjct: 426 VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485 Query: 781 TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS--- 836 G IGS S + VS SE S S ++TV + Sbjct: 486 ASNTGLETTTVFTIGS---DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSE 542 Query: 837 LPSGGSLGLE-KFKKPEGS-------WDCELCLVQNKADSTKCLACESAKPGTKSGFKGF 888 + + GLE EGS E + T + ++ T S Sbjct: 543 TTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSE 602 Query: 889 DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE 948 +T++S+++S +S+ G ++++ + + T+T + + G + S++ ++ Sbjct: 603 NTTASTADSETTSASTTGSETTTASTTSSETTTASTE-GSETTTVSTTDSETTMVSTTGS 661 Query: 949 GFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQE 1008 + G VS+ V + ++ + VS T G Sbjct: 662 ERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTT----GSETTTTS 716 Query: 1009 EKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTS 1068 + E+ +S G T + + SE S+ G+ T +++ + T S Sbjct: 717 TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776 Query: 1069 EAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPK 1128 E A+ G V AS +VF E + + ST+ + Sbjct: 777 IMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAGSE 831 Query: 1129 CQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTADQG 1184 P + G+ + T E S +T S S T + ES + AT G++T+T + +G Sbjct: 832 TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTASTEG 890 Query: 1185 AAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTA 1244 + S + S +T A++ G I ST+ S A+ +++ + + T Sbjct: 891 SETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTV 946 Query: 1245 ESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-- 1302 ++ S+++ S + TT +T + T G+ + +T+G TTT+S GS Sbjct: 947 STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGSET 1003 Query: 1303 SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF 1362 + V TG + S G T T + + G S +TA++ TGS+ T Sbjct: 1004 TTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE----TT 1054 Query: 1363 GTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS 1422 T + S+ S++ S +++ GS TT + + + V+ G+ ++ Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114 Query: 1423 TPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457 T + + + +++ A T GS VF++ Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149 Score = 86.3 bits (212), Expect = 2e-16 Identities = 191/1007 (18%), Positives = 371/1007 (36%), Gaps = 107/1007 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T S T + E +T S + ++ A T + T+ S+ GS S+ ++T ++ Sbjct: 349 TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598 + + + +E++ S+T+ E +S+ T+ ST+ +T EG Sbjct: 409 TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 462 Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658 + GS + G + + + T V+T I S +++ G A Sbjct: 463 TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 515 Query: 659 GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716 S+ + + + ++N ++ ++ + T TG+ET S G + S TG Sbjct: 516 VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 572 Query: 717 DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776 G+ ++ + E T T + + +ET TAS++S Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 630 Query: 777 CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836 TT + GS +V + ++E + SE+ +S S ++TV + Sbjct: 631 SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 679 Query: 837 LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896 G E EGS + + ++ E+ T+ + + S Sbjct: 680 -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732 Query: 897 SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956 + AS+ ++S+ G T ST G + SS++ + M + I Sbjct: 733 TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 788 Query: 957 GDFKFGVSS-ESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELP 1015 G VS+ SK V ++ +S + + S G E Sbjct: 789 GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT--- 845 Query: 1016 KSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEM 1075 +S+ G T + + +SE ++ +G+ T +++ T TS E Sbjct: 846 -TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904 Query: 1076 PATKGGFSFGNVEPASLPSASVFVLGR------TEEKQQEPVTST-SLVFGKKADNEEPK 1128 A+ G V + + G TE + V++T S A+ E Sbjct: 905 TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964 Query: 1129 CQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATF--AFGAQTSTTADQGAA 1186 V + G+ T S++T + + S + ++ T + G++T+T + G Sbjct: 965 T--VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1022 Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246 + S + S +T T+AG T+ S + +++ ++ + TA + Sbjct: 1023 TTITS----TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078 Query: 1247 STSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVF 1306 + ++ S TT+ST + T V+ G S TT S G ATT S+++ Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSETTTVYITG--SKTTTASTEGSEATTVSTTS------ 1130 Query: 1307 GTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVS 1366 S + + G+ T F ++S +T + GS+ + Sbjct: 1131 ----SETTTASTTGSEMTTV--------------FTTVSETTTVSTIGSEATTSSAAGSE 1172 Query: 1367 SSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAA 1426 +++ + + S GS TT S++ GS TT + + + + T G+ +STP++ Sbjct: 1173 ATTTSTEGSETTTASTAGSETTTASTA----GSETTTASTSGSETNTACTTGSETSTPSS 1228 Query: 1427 SAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSS----GTSFSGRKIKT 1469 + +++ AF +GS ++S TS +G + T Sbjct: 1229 AG----------SETNTAFIIGSESTIASTASLEPTATSLTGSETTT 1265 Score = 85.1 bits (209), Expect = 5e-16 Identities = 157/800 (19%), Positives = 285/800 (35%), Gaps = 65/800 (8%) Query: 691 TAKQTGIETP-NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749 TA G ET + +G T + S TG +G+ ++ ET Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146 Query: 750 PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809 T T T + +ET AS++ +TT + E + VS Sbjct: 147 VSTVGSE--TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTT--VSTAGS 202 Query: 810 DNKCVSCMSEKPGSSVPASSSSTVPVSLPSG----GSLGLEKFKKPEGSWDCELCLVQNK 865 + VS + ++ A S +T ++ S + G E GS E + Sbjct: 203 ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---ETTAASTE 259 Query: 866 ADSTKCLACESAKPGTKSGFKGFDTSSSSSNSA----ASSSFKFGVSSSSSGPSQTLTST 921 T E +K T S GF+T+++S+ + AS+ +S+ GP T ST Sbjct: 260 DSETNTAFTEDSKTTTAST-TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVST 318 Query: 922 GN------FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975 + F G + V S++ +++ + +G S+ Sbjct: 319 ASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTAST 378 Query: 976 SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035 ++ + VS T + ++ E + S T +T + Sbjct: 379 EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438 Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095 + +T + S T T+ + T SE K A G L + Sbjct: 439 EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT----AYTTGSETTTASNTGLETT 494 Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK-----DENSSKST 1150 +VF +G + T+ V ++ S SE T E ++ ST Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSE------MTTVSTEGSENTTVSTTGSETTTVST 548 Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210 T S + SE +T GA+T+T + +G S +T A++AG Sbjct: 549 TGLETTTTSTEGSEMTTVSTT--GAETTTDSTEG--------------SGTTAASTAGSE 592 Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV 1270 ST+ S A+ ++++ ++ + TA +++S++ S + TT ST + Sbjct: 593 TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652 Query: 1271 TPFVFGPGA--------SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGAN 1322 T V G+ S TT S G T ++ +G++ V TG S G+ Sbjct: 653 TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-GSE 711 Query: 1323 QTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380 T T + + + G + ++ST + T S T ++ S+ S+ Sbjct: 712 TTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771 Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440 + S ++ A GS TT + ++ + VFT + ++ + +A + + ++ Sbjct: 772 TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831 Query: 1441 SPAAFTVGSNGKNVFSSSGT 1460 + A T GS S+ G+ Sbjct: 832 TIPASTAGSETTTTTSTEGS 851 Score = 79.0 bits (193), Expect = 3e-14 Identities = 193/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%) Query: 478 PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537 P S+ T + + E TT ++ A T + T+PS TGS S + T Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 68 Query: 538 NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582 + + + + TA ++GS +T+ E + S+ TT NS Sbjct: 69 STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS 128 Query: 583 TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642 T +T G E + + + S + DS + T + T Sbjct: 129 TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180 Query: 643 SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702 S + + G S+ +T + ++ + ++ + T + Sbjct: 181 GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 240 Query: 703 SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758 +TT+S +G+ T D +T +K ET T + + Sbjct: 241 GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295 Query: 759 TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810 T+ SE+ ET S++S VTT + + +GS VS + Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 352 Query: 811 NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869 S M SE S S ++T + E + S + DS Sbjct: 353 TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412 Query: 870 KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923 C T F+T+++S+ A++S + +S+ + T+T+ G+ Sbjct: 413 TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 472 Query: 924 FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979 K G + +S++G ++ + + G VS+ ++ Sbjct: 473 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532 Query: 980 NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039 N + + VS T G+ + E+ S+ G T +ST T Sbjct: 533 NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 585 Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099 ++ + + T ++++ + + +T+ A T + AS + Sbjct: 586 ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 645 Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156 + T+ + + ST+ E + V + G+ E S +T S + T Sbjct: 646 VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 703 Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208 K S SE +T G++T+T + +G+ S + S +T A++ G Sbjct: 704 KVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 759 Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265 +ST+SS +A+ + S ++S+ T + ST+ S +F+++S+ S+ Sbjct: 760 SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817 Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317 T TA + + A S TTT+ TTT+S+ GS + T S + + Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877 Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375 G+ T + + + G + ++ST + T S T + S+ Sbjct: 878 TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937 Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435 + S+ S T + + GS TT + + T G+ ++T + + + + Sbjct: 938 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 997 Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460 +++ + GS V S++GT Sbjct: 998 IEGSETTTVSSTGSETTTV-STTGT 1021 Score = 75.5 bits (184), Expect = 4e-13 Identities = 189/936 (20%), Positives = 323/936 (34%), Gaps = 102/936 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTE--- 536 T S + T + E TT S + ++ T ++ T+ S+ GS M S+ ++T Sbjct: 519 TGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST 578 Query: 537 --ANVLPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDC 593 + S+ G T +V A + + S++ E +S+ TT ST +T Sbjct: 579 EGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAST 638 Query: 594 EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSS----G 649 EG + S ++ + G + I S T T + +S+ S Sbjct: 639 EGS-ETTTVSTTDSETTMVSTTG-SERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696 Query: 650 IGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTT 707 I E+ K ++ T T+ I + S TA G ET S G T Sbjct: 697 ITGSETTKVSTTGSETT----TTSTEGSEITTASITGSETTTASTEGSETTTASTEGSET 752 Query: 708 LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767 SAS TG + ++ ++ + ET K T + T V +E++ Sbjct: 753 TSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT--VFTENS 810 Query: 768 ETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPA 827 ET AS+++ TT + + E + + +E + SE +S + Sbjct: 811 ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTES 870 Query: 828 SSSSTVPVSLPSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886 S ++T ++G E EGS E + T + E ++ T S Sbjct: 871 SETTTAT-------TIGSETTTASTEGS---ETTTTSTEGSETTTASTEGSEITTVS--- 917 Query: 887 GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS---SDSGSI 943 ++ S + AS+ ++S+ G T ST G I VS S++ ++ Sbjct: 918 ----TTGSETTTASTEGSETTTASTEGSELTTVST-------TGSETITVSAEGSETTTV 966 Query: 944 NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVS 1003 M + G VS+ ++ + + VS T + ++ Sbjct: 967 TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTIT 1026 Query: 1004 NLGQEEKKEELPKSSSAGFSFGTG---VINSTPAPANTIVTSENKSSFNLGTIETKSASV 1060 + E S + TG ST T V++ + T + ++ +V Sbjct: 1027 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTV 1086 Query: 1061 APFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS---LV 1117 + T+ A T + AS + + T + T+ S V Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146 Query: 1118 FGKKADNEEPKC----QPVFSFGNSEQTK-----DENSSKSTFSFSMTKPSEKESEQPAK 1168 F ++ S SE T E ++ ST T S SE Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTA 1206 Query: 1169 ATFAF--------GAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSN 1220 +T G++TST + G+ + + S+ +ST +S Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIAST---------------ASL 1251 Query: 1221 PPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGAS 1280 P AT + G + VS +A G TA S+T S F T +T ++ P P + Sbjct: 1252 EPTATSLTGSETTTVSITASGATAASTTVSSTTF------VLTKATDVSIQPITNTPMSG 1305 Query: 1281 SNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPG 1340 + T G T +SS + + T +A P N + + GAS Sbjct: 1306 TRTT-----GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAH 1360 Query: 1341 FGSISSSTALFPTGS---QPAPPTFG--TVSSSSQP 1371 ++ + PT S + P + G TVS S P Sbjct: 1361 GVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTP 1396 Score = 54.3 bits (129), Expect = 9e-07 Identities = 165/869 (18%), Positives = 302/869 (34%), Gaps = 104/869 (11%) Query: 476 SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535 S T S T + +S E TT+S ++ T + T S+TGS S+ ++T Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674 Query: 536 -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586 E V S T S+ ++T ++S GS +T S+ +TT + T Sbjct: 675 TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---TTSTEGSEITTASITG-S 730 Query: 587 KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646 +T EG EGS + G ++ A T++ + + + Sbjct: 731 ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 784 Query: 647 SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706 +S IG + + +S + T +N ++ + A++ + TA I +T Sbjct: 785 ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 842 Query: 707 TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766 T + S G G+ ++ + ET T + + T T +E Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 900 Query: 767 AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 +ET TAS+ +TT + + S + S + ++V Sbjct: 901 SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 947 Query: 827 ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886 + S T+ VS EGS + + ++ + E+ T Sbjct: 948 TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993 Query: 887 GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946 + S + SS+ + S++G T+TST G + S++ ++ Sbjct: 994 TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAV--- 1046 Query: 947 SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006 + SE+ + G + ++ L S G Sbjct: 1047 --------------YTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066 ++++ + TG +T + + T+ + +S T T + + Sbjct: 1093 TTTASTAGSETTTV---YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149 Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126 SE T + G+ S + S TE + T+T+ G + Sbjct: 1150 VSE--------TTTVSTIGSEATTSSAAGSEATTTSTEGSE----TTTASTAGSETTTAS 1197 Query: 1127 PKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAA 1186 + S E ++ T + PS SE F G++ ST A + Sbjct: 1198 TAGSETTTASTS---GSETNTACTTGSETSTPSSAGSE--TNTAFIIGSE-STIASTASL 1251 Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF------ 1240 +P + L + S ++T + +A G S+T SS V T S P++++ Sbjct: 1252 EPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1309 Query: 1241 GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTSS 1298 G +S+S ++ D + S T + G G S+ ++TTS G TT S+ Sbjct: 1310 GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369 Query: 1299 SAGSSFVF-GTGPSAPSASPAFGANQTPT 1326 +S F TGP + + + TPT Sbjct: 1370 REPTSSTFQETGPVSMGTN-TVSMSHTPT 1397 Score = 41.6 bits (96), Expect = 0.006 Identities = 50/197 (25%), Positives = 80/197 (40%), Gaps = 29/197 (14%) Query: 1277 PGASSNNTTTSGFGF---------GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327 P A SN TT S G TTT+S+AGS T PS + + Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET---TTPSPTGSQTTIVSISGSEI 65 Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ-SAFGSG 1386 + A N + S +T GS+ T G S ++ + G + + SA GS Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG--SETTTVSITGTETTMVSAMGSE 123 Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446 TT NS+++ S TT + + + V T G+ ++T + +++ AA T Sbjct: 124 TTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYTAD----------SETTAAST 169 Query: 1447 VGSNGKNVFSSSGTSFS 1463 GS VF++ + + Sbjct: 170 TGSEMTTVFTAGSETIT 186 >gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] Length = 1542 Score = 99.4 bits (246), Expect = 2e-20 Identities = 207/1055 (19%), Positives = 376/1055 (35%), Gaps = 112/1055 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 TSS + + E TT S ++ A T + T+ S+TGS M + + + + Sbjct: 151 TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM----TTVFTAGSETI 206 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599 P ++ T +V A + + S++ E +S+AH TT ST +T G Sbjct: 207 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 266 Query: 600 AE------------------ILKEGSVLDILKSPGFASPKIDSVAAQPTATS-------- 633 E S + GF + + ++PT S Sbjct: 267 VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTM 326 Query: 634 -----PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-- 686 P SS ++ G S+ +T + ++ + ++ Sbjct: 327 ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 386 Query: 687 -----SPRDTAKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEA 739 S TA G ET S G + S TG + + TC ++ A Sbjct: 387 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 446 Query: 740 IKCVACETPKPGT------------------CVKRALTLTVVSESAETMTA-SSSSCTVT 780 + ET T + + T TV + +ET TA ++ S T T Sbjct: 447 VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 506 Query: 781 TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS--- 836 G IGS S + VS SE S S ++TV + Sbjct: 507 ASNTGLETTTVFTIGS---DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSE 563 Query: 837 LPSGGSLGLE-KFKKPEGS-------WDCELCLVQNKADSTKCLACESAKPGTKSGFKGF 888 + + GLE EGS E + T + ++ T S Sbjct: 564 TTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSE 623 Query: 889 DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE 948 +T++S+++S +S+ G ++++ + + T+T + + G + S++ ++ Sbjct: 624 NTTASTADSETTSASTTGSETTTASTTSSETTTASTE-GSETTTVSTTDSETTMVSTTGS 682 Query: 949 GFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQE 1008 + G VS+ V + ++ + VS T G Sbjct: 683 ERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTT----GSETTTTS 737 Query: 1009 EKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTS 1068 + E+ +S G T + + SE S+ G+ T +++ + T S Sbjct: 738 TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 797 Query: 1069 EAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPK 1128 E A+ G V AS +VF E + + ST+ + Sbjct: 798 IMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAGSE 852 Query: 1129 CQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTADQG 1184 P + G+ + T E S +T S S T + ES + AT G++T+T + +G Sbjct: 853 TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTASTEG 911 Query: 1185 AAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTA 1244 + S + S +T A++ G I ST+ S A+ +++ + + T Sbjct: 912 SETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTV 967 Query: 1245 ESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-- 1302 ++ S+++ S + TT +T + T G+ + +T+G TTT+S GS Sbjct: 968 STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGSET 1024 Query: 1303 SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF 1362 + V TG + S G T T + + G S +TA++ TGS+ T Sbjct: 1025 TTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE----TT 1075 Query: 1363 GTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS 1422 T + S+ S++ S +++ GS TT + + + V+ G+ ++ Sbjct: 1076 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1135 Query: 1423 TPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457 T + + + +++ A T GS VF++ Sbjct: 1136 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1170 Score = 95.1 bits (235), Expect = 4e-19 Identities = 206/1019 (20%), Positives = 385/1019 (37%), Gaps = 104/1019 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T++S F ++ T S P+ ++ + T P +T V + + Sbjct: 295 TTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET 354 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599 + S++G + T +GS +T I+ S T+ +ST +T EG Sbjct: 355 IRASTVGSETT-----TVSTTGSETTTASIMGSE----TSTDSTTGSETTTASTEGS-ET 404 Query: 600 AEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF-----SSSGIGFGE 654 EGS + + G + + ++ T T A+S+ ++S G Sbjct: 405 TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 464 Query: 655 SLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-----SPRDTAKQTGIETPN--KSGKTT 707 ++ + S + T + T A K S TA TG+ET G T Sbjct: 465 TIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDT 524 Query: 708 LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767 +AS G G+ ++ + ET T T T +E + Sbjct: 525 TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLE--TTTTSTEGS 582 Query: 768 ETMTASSSSCTVTT-GTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 E T S++ TT T G G GS +V ++E+ + SE +S Sbjct: 583 EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA--DSENTTASTADSETTSASTT 640 Query: 827 ASSSSTVPVSLPSGGSLGLEKFKKPEGSW-DCELCLVQNKADSTKCLACESAKPGTKSGF 885 S ++T + + E + S D E +V + E ++ T S Sbjct: 641 GSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSA- 699 Query: 886 KGFDTSSSSSNSAASSSFKFGVSS---SSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGS 942 G +T+ S+ S ++ G + S++G T TST G +I +S +GS Sbjct: 700 TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTE--------GSEITTASITGS 751 Query: 943 --INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQF 1000 +EG + + + S+ + E S + + ++S + + ++ Sbjct: 752 ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSS-ETTMASIMGSETTMA---- 806 Query: 1001 GVSNLGQEEKKEELPKSSSAGF---SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS 1057 S +G E K S + T + ++T + T+ T+ ++ TI + Sbjct: 807 --STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE------TIPAST 858 Query: 1058 ASVAPFTCKTSEAKKEEMPATKGG-FSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSL 1116 A T ++E + +T+G + + E + +A+ T + T+T+ Sbjct: 859 AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 918 Query: 1117 VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQ 1176 G + + + + T E ++ ST T S + SE +T G++ Sbjct: 919 TEGSETTTASTEGSEITTVST---TGSETTTASTEGSETTTASTEGSELTTVSTT--GSE 973 Query: 1177 TSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVS 1236 T T + +G+ + + S +T A++AG ST+ S A+ + G + VS Sbjct: 974 TITVSAEGSETTTVTTMG----SETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVS 1028 Query: 1237 SSAFGNTAESST-SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATT 1295 S+ T S+T +++ + S + TT +T + T V+ G+ + T+T G TT Sbjct: 1029 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG---SETT 1085 Query: 1296 TSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGS 1355 T S+ GS + A A+ T + G+ GS +T ++ TGS Sbjct: 1086 TVSTTGSE-----------TTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGS 1132 Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415 + T ++S++ S++ S T+ +++A GS T T + + V Sbjct: 1133 K-------TTTASTEG-------SEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVS 1178 Query: 1416 TFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSG----TSFSGRKIKTA 1470 T G+ ++T +A+ + + +++ A T GS ++ S SG + TA Sbjct: 1179 TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTA 1237 Score = 87.0 bits (214), Expect = 1e-16 Identities = 173/891 (19%), Positives = 331/891 (37%), Gaps = 89/891 (9%) Query: 630 TATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLS-P 688 TA S V+ T ++SS ++ G + S+ +T + K ++ + ++ + P Sbjct: 11 TADSKVI-TASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTP 69 Query: 689 RDTAKQTGIETPNKSGKTTLSASGT--------GFGDKFKPVIGTWDCDTCLVQNKPEAI 740 T QT I + + S TT S +G+ G G + G+ + ++ + Sbjct: 70 SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGS-ESTISTAGSETTTV 128 Query: 741 KCVACETPKPGTCVKRALT-LTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWEC 799 ET T T SE+ T TA S + TV+T G + + Sbjct: 129 SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVST----VGSETTTAYTADSE 184 Query: 800 SVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCEL 859 + + +E + SE S S ++TV + ++ GS Sbjct: 185 TTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTT------GSETTTA 238 Query: 860 CLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLT 919 ++ + + E+ K T T+ S + +A++ + + + + T + Sbjct: 239 STAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAS 298 Query: 920 STGNFKFGDQGGFKIGVSSDSGS----INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975 +TG F+ +S +GS + M + IG VS+ S Sbjct: 299 TTG---------FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFA 349 Query: 976 SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035 + ++ + + VS T + +++ E + S+ G T ST Sbjct: 350 AGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTD----STTGSETTTA---STEGS 402 Query: 1036 ANTIVTSENKSSFNLGTI--ETKSASVAPFTCKTSEAKKEEMPA-------TKGGFSFGN 1086 T ++E + + T ET + S+ T+ + EM A T + G+ Sbjct: 403 ETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGS 462 Query: 1087 VEPASLPSASVFVLGRTEEKQQEPVTS------TSLVFGKK---ADNEEPKCQPVFSFGN 1137 + S S TE + VT+ T+ G + A N + VF+ G+ Sbjct: 463 EITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGS 522 Query: 1138 SEQTKDENSSKSTF----SFSMTKPSEKESEQPAKATFAF--------GAQTSTTADQGA 1185 T S++T MT S + SE +T G +T+TT+ +G+ Sbjct: 523 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGS 582 Query: 1186 AKPVFSFL------NNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSA 1239 S +++ S +T A++AG ST+ S A+ ++++ ++ + Sbjct: 583 EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGS 642 Query: 1240 FGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGA--------SSNNTTTSGFGF 1291 TA +++S++ S + TT ST + T V G+ S TT S G Sbjct: 643 ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 702 Query: 1292 GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSST--A 1349 T ++ +G++ V TG S G+ T T + + + G + ++ST + Sbjct: 703 ETTVSTEGSGTTTVSITGSETTKVSTT-GSETTTTSTEGSEITTASITGSETTTASTEGS 761 Query: 1350 LFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNN 1409 T S T ++ S+ S++ S ++ A GS TT + ++ Sbjct: 762 ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 821 Query: 1410 SPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGT 1460 + VFT + ++ + +A + + +++ A T GS S+ G+ Sbjct: 822 KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 872 Score = 86.7 bits (213), Expect = 2e-16 Identities = 186/973 (19%), Positives = 359/973 (36%), Gaps = 75/973 (7%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T S T + E +T S + ++ A T + T+ S+ GS S+ ++T ++ Sbjct: 370 TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 429 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598 + + + +E++ S+T+ E +S+ T+ ST+ +T EG Sbjct: 430 TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 483 Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658 + GS + G + + + T V+T I S +++ G A Sbjct: 484 TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 536 Query: 659 GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716 S+ + + + ++N ++ ++ + T TG+ET S G + S TG Sbjct: 537 VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 593 Query: 717 DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776 G+ ++ + E T T + + +ET TAS++S Sbjct: 594 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 651 Query: 777 CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836 TT + GS +V + ++E + SE+ +S S ++TV + Sbjct: 652 SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 700 Query: 837 LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896 G E EGS + + ++ E+ T+ + + S Sbjct: 701 -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 753 Query: 897 SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956 + AS+ ++S+ G T ST G + SS++ + M + I Sbjct: 754 TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 809 Query: 957 GDFKFGVSS-ESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELP 1015 G VS+ SK V ++ +S + + S G E Sbjct: 810 GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT--- 866 Query: 1016 KSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEM 1075 +S+ G T + + +SE ++ +G+ T +++ T TS E Sbjct: 867 -TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 925 Query: 1076 PATKGGFSFGNVEPASLPSASVFVLGR------TEEKQQEPVTST-SLVFGKKADNEEPK 1128 A+ G V + + G TE + V++T S A+ E Sbjct: 926 TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 985 Query: 1129 CQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATF--AFGAQTSTTADQGAA 1186 V + G+ T S++T + + S + ++ T + G++T+T + G Sbjct: 986 T--VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1043 Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246 + S + S +T T+AG T+ S + +++ ++ + TA + Sbjct: 1044 TTITS----TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1099 Query: 1247 STSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSG-------FGFGATTTSSS 1299 + ++ S TT+ST + T V+ G+ + +T G TTT+S+ Sbjct: 1100 ADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAST 1159 Query: 1300 AGSSF--VFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTA--LFPTGS 1355 GS VF T + S G+ T + A+ + G + ++STA T S Sbjct: 1160 TGSEMTTVFTTVSETTTVS-TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1218 Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415 T +S S+ S+++ S +++AF GS TT + + P+ Sbjct: 1219 TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATS 1278 Query: 1416 TFGANSSTPAASA 1428 G+ ++T + +A Sbjct: 1279 LTGSETTTVSITA 1291 Score = 80.5 bits (197), Expect = 1e-14 Identities = 194/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%) Query: 478 PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537 P S+ T + + E TT ++ A T + T+PS TGS S + T Sbjct: 30 PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 89 Query: 538 NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582 + + + + TA ++GS ST+ E + S+ TT NS Sbjct: 90 STAGSENTTVSSAGSGTTTASMAGSESTISTAGSETTTVSITGTETTMVSAMGSETTTNS 149 Query: 583 TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642 T +T G E + + + S + DS + T + T Sbjct: 150 TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 201 Query: 643 SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702 S + + G S+ +T + ++ + ++ + T + Sbjct: 202 GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 261 Query: 703 SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758 +TT+S +G+ T D +T +K ET T + + Sbjct: 262 GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 316 Query: 759 TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810 T+ SE+ ET S++S VTT + + +GS VS + Sbjct: 317 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 373 Query: 811 NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869 S M SE S S ++T + E + S + DS Sbjct: 374 TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 433 Query: 870 KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923 C T F+T+++S+ A++S + +S+ + T+T+ G+ Sbjct: 434 TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 493 Query: 924 FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979 K G + +S++G ++ + + G VS+ ++ Sbjct: 494 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 553 Query: 980 NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039 N + + VS T G+ + E+ S+ G T +ST T Sbjct: 554 NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 606 Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099 ++ + + T ++++ + + +T+ A T + AS + Sbjct: 607 ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 666 Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156 + T+ + + ST+ E + V + G+ E S +T S + T Sbjct: 667 VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 724 Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208 K S SE +T G++T+T + +G+ S + S +T A++ G Sbjct: 725 KVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 780 Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265 +ST+SS +A+ + S ++S+ T + ST+ S +F+++S+ S+ Sbjct: 781 SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 838 Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317 T TA + + A S TTT+ TTT+S+ GS + T S + + Sbjct: 839 TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 898 Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375 G+ T + + + G + ++ST + T S T + S+ Sbjct: 899 TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 958 Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435 + S+ S T + + GS TT + + T G+ ++T + + + + Sbjct: 959 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 1018 Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460 +++ + GS V S++GT Sbjct: 1019 IEGSETTTVSSTGSETTTV-STTGT 1042 Score = 74.3 bits (181), Expect = 8e-13 Identities = 188/936 (20%), Positives = 323/936 (34%), Gaps = 102/936 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTE--- 536 T S + T + E TT S + ++ T ++ T+ S+ GS M S+ ++T Sbjct: 540 TGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST 599 Query: 537 --ANVLPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDC 593 + S+ G T +V A + + S++ E +S+ TT ST +T Sbjct: 600 EGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAST 659 Query: 594 EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSS----G 649 EG + S ++ + G + I S T T + +S+ S Sbjct: 660 EGS-ETTTVSTTDSETTMVSTTG-SERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 717 Query: 650 IGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTT 707 I E+ K ++ T T+ I + S TA G ET S G T Sbjct: 718 ITGSETTKVSTTGSETT----TTSTEGSEITTASITGSETTTASTEGSETTTASTEGSET 773 Query: 708 LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767 SAS TG + ++ ++ + ET K T + T V +E++ Sbjct: 774 TSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT--VFTENS 831 Query: 768 ETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPA 827 ET AS+++ TT + + E + + +E + SE +S + Sbjct: 832 ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTES 891 Query: 828 SSSSTVPVSLPSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886 S ++T ++G E EGS E + T + E ++ T S Sbjct: 892 SETTTAT-------TIGSETTTASTEGS---ETTTTSTEGSETTTASTEGSEITTVS--- 938 Query: 887 GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS---SDSGSI 943 ++ S + AS+ ++S+ G T ST G I VS S++ ++ Sbjct: 939 ----TTGSETTTASTEGSETTTASTEGSELTTVST-------TGSETITVSAEGSETTTV 987 Query: 944 NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVS 1003 M + G VS+ ++ + + VS T + ++ Sbjct: 988 TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTIT 1047 Query: 1004 NLGQEEKKEELPKSSSAGFSFGTG---VINSTPAPANTIVTSENKSSFNLGTIETKSASV 1060 + E S + TG ST T V++ + T + ++ +V Sbjct: 1048 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTV 1107 Query: 1061 APFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS---LV 1117 + T+ A T + AS + + T + T+ S V Sbjct: 1108 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1167 Query: 1118 FGKKADNEEPKC----QPVFSFGNSEQTK-----DENSSKSTFSFSMTKPSEKESEQPAK 1168 F ++ S SE T E ++ ST T S SE Sbjct: 1168 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTA 1227 Query: 1169 ATFAF--------GAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSN 1220 +T G++TST + G+ + + ++ +ST +S Sbjct: 1228 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAST---------------ASL 1272 Query: 1221 PPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGAS 1280 P AT + G + VS +A G TA S+T S F T +T ++ P P + Sbjct: 1273 EPTATSLTGSETTTVSITASGATAASTTVSSTTF------VLTKATDVSIQPITNTPMSG 1326 Query: 1281 SNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPG 1340 + T G T +SS + + T +A P N + + GAS Sbjct: 1327 TRTT-----GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAH 1381 Query: 1341 FGSISSSTALFPTGS---QPAPPTFG--TVSSSSQP 1371 ++ + PT S + P + G TVS S P Sbjct: 1382 GVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTP 1417 Score = 54.7 bits (130), Expect = 7e-07 Identities = 165/869 (18%), Positives = 302/869 (34%), Gaps = 104/869 (11%) Query: 476 SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535 S T S T + +S E TT+S ++ T + T S+TGS S+ ++T Sbjct: 636 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 695 Query: 536 -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586 E V S T S+ ++T ++S GS +T S+ +TT + T Sbjct: 696 TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---TTSTEGSEITTASITG-S 751 Query: 587 KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646 +T EG EGS + G ++ A T++ + + + Sbjct: 752 ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 805 Query: 647 SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706 +S IG + + +S + T +N ++ + A++ + TA I +T Sbjct: 806 ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 863 Query: 707 TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766 T + S G G+ ++ + ET T + + T T +E Sbjct: 864 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 921 Query: 767 AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 +ET TAS+ +TT + + S + S + ++V Sbjct: 922 SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 968 Query: 827 ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886 + S T+ VS EGS + + ++ + E+ T Sbjct: 969 TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 1014 Query: 887 GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946 + S + SS+ + S++G T+TST G + S++ ++ Sbjct: 1015 TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAV--- 1067 Query: 947 SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006 + SE+ + G + ++ L S G Sbjct: 1068 --------------YTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1113 Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066 ++++ + TG +T + + T+ + +S T T + + Sbjct: 1114 TTTASTAGSETTTV---YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1170 Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126 SE T + G+ S + S TE + T+T+ G + Sbjct: 1171 VSE--------TTTVSTIGSEATTSSAAGSEATTTSTEGSE----TTTASTAGSETTTAS 1218 Query: 1127 PKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAA 1186 + S E ++ T + PS SE F G++T T A + Sbjct: 1219 TAGSETTTASTS---GSETNTACTTGSETSTPSSAGSE--TNTAFIIGSET-TIASTASL 1272 Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF------ 1240 +P + L + S ++T + +A G S+T SS V T S P++++ Sbjct: 1273 EPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1330 Query: 1241 GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTSS 1298 G +S+S ++ D + S T + G G S+ ++TTS G TT S+ Sbjct: 1331 GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1390 Query: 1299 SAGSSFVF-GTGPSAPSASPAFGANQTPT 1326 +S F TGP + + + TPT Sbjct: 1391 REPTSSTFQETGPVSMGTN-TVSMSHTPT 1418 Score = 51.6 bits (122), Expect = 6e-06 Identities = 66/271 (24%), Positives = 108/271 (39%), Gaps = 30/271 (11%) Query: 1210 GIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESST--SQSLLFSQDSKLATTSSTG 1267 G ++TS+++ V T S V+ +A NT +ST S++ + TT+ST Sbjct: 3 GSEATTTSTADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTA 62 Query: 1268 TAVTPFVFGPG------------------ASSNNTTTSGFGFGATTTSSSAGSSFVFGTG 1309 + T G A S NTT S G G TTT+S AGS T Sbjct: 63 GSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSG-TTTASMAGSESTISTA 121 Query: 1310 PSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSS 1369 S + G T + + + +STA GS+ T TV S + Sbjct: 122 GSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTA----GSETT--TVSTVGSET 175 Query: 1370 QPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQ 1429 S++ S T ++ F GS T + + + V T G+ ++T + + Sbjct: 176 TTAYTAD--SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGS 233 Query: 1430 PSGSGGFPFNQSPAAFTVGSNGKNVFSSSGT 1460 + + +++ AA T+GS V S++G+ Sbjct: 234 ETTTASTAHSETTAASTMGSETTKV-STAGS 263 Score = 47.8 bits (112), Expect = 8e-05 Identities = 57/217 (26%), Positives = 89/217 (41%), Gaps = 32/217 (14%) Query: 1257 DSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGF---------GATTTSSSAGSSFVFG 1307 DSK+ T SS + T P A SN TT S G TTT+S+AGS Sbjct: 13 DSKVITASSMSSETT---VAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSET--- 66 Query: 1308 TGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSS 1367 T PS + + + A N + S +T GS+ T G S Sbjct: 67 TTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAG--SE 124 Query: 1368 SSQPPVFGQQPSQ-SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAA 1426 ++ + G + + SA GS TT NS+++ S TT + + + V T G+ ++T Sbjct: 125 TTTVSITGTETTMVSAMGSETTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYT 180 Query: 1427 SAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463 + +++ AA T GS VF++ + + Sbjct: 181 AD----------SETTAASTTGSEMTTVFTAGSETIT 207 >gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] Length = 1612 Score = 99.4 bits (246), Expect = 2e-20 Identities = 207/1055 (19%), Positives = 376/1055 (35%), Gaps = 112/1055 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 TSS + + E TT S ++ A T + T+ S+TGS M + + + + Sbjct: 130 TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM----TTVFTAGSETI 185 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599 P ++ T +V A + + S++ E +S+AH TT ST +T G Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245 Query: 600 AE------------------ILKEGSVLDILKSPGFASPKIDSVAAQPTATS-------- 633 E S + GF + + ++PT S Sbjct: 246 VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTM 305 Query: 634 -----PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-- 686 P SS ++ G S+ +T + ++ + ++ Sbjct: 306 ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365 Query: 687 -----SPRDTAKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEA 739 S TA G ET S G + S TG + + TC ++ A Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425 Query: 740 IKCVACETPKPGT------------------CVKRALTLTVVSESAETMTA-SSSSCTVT 780 + ET T + + T TV + +ET TA ++ S T T Sbjct: 426 VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485 Query: 781 TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS--- 836 G IGS S + VS SE S S ++TV + Sbjct: 486 ASNTGLETTTVFTIGS---DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSE 542 Query: 837 LPSGGSLGLE-KFKKPEGS-------WDCELCLVQNKADSTKCLACESAKPGTKSGFKGF 888 + + GLE EGS E + T + ++ T S Sbjct: 543 TTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSE 602 Query: 889 DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE 948 +T++S+++S +S+ G ++++ + + T+T + + G + S++ ++ Sbjct: 603 NTTASTADSETTSASTTGSETTTASTTSSETTTASTE-GSETTTVSTTDSETTMVSTTGS 661 Query: 949 GFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQE 1008 + G VS+ V + ++ + VS T G Sbjct: 662 ERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTT----GSETTTTS 716 Query: 1009 EKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTS 1068 + E+ +S G T + + SE S+ G+ T +++ + T S Sbjct: 717 TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776 Query: 1069 EAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPK 1128 E A+ G V AS +VF E + + ST+ + Sbjct: 777 IMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAGSE 831 Query: 1129 CQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTADQG 1184 P + G+ + T E S +T S S T + ES + AT G++T+T + +G Sbjct: 832 TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTASTEG 890 Query: 1185 AAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTA 1244 + S + S +T A++ G I ST+ S A+ +++ + + T Sbjct: 891 SETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTV 946 Query: 1245 ESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-- 1302 ++ S+++ S + TT +T + T G+ + +T+G TTT+S GS Sbjct: 947 STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGSET 1003 Query: 1303 SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF 1362 + V TG + S G T T + + G S +TA++ TGS+ T Sbjct: 1004 TTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE----TT 1054 Query: 1363 GTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS 1422 T + S+ S++ S +++ GS TT + + + V+ G+ ++ Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114 Query: 1423 TPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457 T + + + +++ A T GS VF++ Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149 Score = 95.1 bits (235), Expect = 4e-19 Identities = 206/1019 (20%), Positives = 385/1019 (37%), Gaps = 104/1019 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T++S F ++ T S P+ ++ + T P +T V + + Sbjct: 274 TTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET 333 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599 + S++G + T +GS +T I+ S T+ +ST +T EG Sbjct: 334 IRASTVGSETT-----TVSTTGSETTTASIMGSE----TSTDSTTGSETTTASTEGS-ET 383 Query: 600 AEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF-----SSSGIGFGE 654 EGS + + G + + ++ T T A+S+ ++S G Sbjct: 384 TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443 Query: 655 SLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-----SPRDTAKQTGIETPN--KSGKTT 707 ++ + S + T + T A K S TA TG+ET G T Sbjct: 444 TIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDT 503 Query: 708 LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767 +AS G G+ ++ + ET T T T +E + Sbjct: 504 TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLE--TTTTSTEGS 561 Query: 768 ETMTASSSSCTVTT-GTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 E T S++ TT T G G GS +V ++E+ + SE +S Sbjct: 562 EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA--DSENTTASTADSETTSASTT 619 Query: 827 ASSSSTVPVSLPSGGSLGLEKFKKPEGSW-DCELCLVQNKADSTKCLACESAKPGTKSGF 885 S ++T + + E + S D E +V + E ++ T S Sbjct: 620 GSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSA- 678 Query: 886 KGFDTSSSSSNSAASSSFKFGVSS---SSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGS 942 G +T+ S+ S ++ G + S++G T TST G +I +S +GS Sbjct: 679 TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTE--------GSEITTASITGS 730 Query: 943 --INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQF 1000 +EG + + + S+ + E S + + ++S + + ++ Sbjct: 731 ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSS-ETTMASIMGSETTMA---- 785 Query: 1001 GVSNLGQEEKKEELPKSSSAGF---SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS 1057 S +G E K S + T + ++T + T+ T+ ++ TI + Sbjct: 786 --STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE------TIPAST 837 Query: 1058 ASVAPFTCKTSEAKKEEMPATKGG-FSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSL 1116 A T ++E + +T+G + + E + +A+ T + T+T+ Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897 Query: 1117 VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQ 1176 G + + + + T E ++ ST T S + SE +T G++ Sbjct: 898 TEGSETTTASTEGSEITTVST---TGSETTTASTEGSETTTASTEGSELTTVSTT--GSE 952 Query: 1177 TSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVS 1236 T T + +G+ + + S +T A++AG ST+ S A+ + G + VS Sbjct: 953 TITVSAEGSETTTVTTMG----SETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVS 1007 Query: 1237 SSAFGNTAESST-SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATT 1295 S+ T S+T +++ + S + TT +T + T V+ G+ + T+T G TT Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG---SETT 1064 Query: 1296 TSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGS 1355 T S+ GS + A A+ T + G+ GS +T ++ TGS Sbjct: 1065 TVSTTGSE-----------TTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGS 1111 Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415 + T ++S++ S++ S T+ +++A GS T T + + V Sbjct: 1112 K-------TTTASTEG-------SEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVS 1157 Query: 1416 TFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSG----TSFSGRKIKTA 1470 T G+ ++T +A+ + + +++ A T GS ++ S SG + TA Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTA 1216 Score = 86.7 bits (213), Expect = 2e-16 Identities = 186/973 (19%), Positives = 359/973 (36%), Gaps = 75/973 (7%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T S T + E +T S + ++ A T + T+ S+ GS S+ ++T ++ Sbjct: 349 TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598 + + + +E++ S+T+ E +S+ T+ ST+ +T EG Sbjct: 409 TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 462 Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658 + GS + G + + + T V+T I S +++ G A Sbjct: 463 TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 515 Query: 659 GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716 S+ + + + ++N ++ ++ + T TG+ET S G + S TG Sbjct: 516 VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 572 Query: 717 DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776 G+ ++ + E T T + + +ET TAS++S Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 630 Query: 777 CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836 TT + GS +V + ++E + SE+ +S S ++TV + Sbjct: 631 SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 679 Query: 837 LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896 G E EGS + + ++ E+ T+ + + S Sbjct: 680 -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732 Query: 897 SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956 + AS+ ++S+ G T ST G + SS++ + M + I Sbjct: 733 TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 788 Query: 957 GDFKFGVSS-ESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELP 1015 G VS+ SK V ++ +S + + S G E Sbjct: 789 GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT--- 845 Query: 1016 KSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEM 1075 +S+ G T + + +SE ++ +G+ T +++ T TS E Sbjct: 846 -TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904 Query: 1076 PATKGGFSFGNVEPASLPSASVFVLGR------TEEKQQEPVTST-SLVFGKKADNEEPK 1128 A+ G V + + G TE + V++T S A+ E Sbjct: 905 TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964 Query: 1129 CQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATF--AFGAQTSTTADQGAA 1186 V + G+ T S++T + + S + ++ T + G++T+T + G Sbjct: 965 T--VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1022 Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246 + S + S +T T+AG T+ S + +++ ++ + TA + Sbjct: 1023 TTITS----TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078 Query: 1247 STSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSG-------FGFGATTTSSS 1299 + ++ S TT+ST + T V+ G+ + +T G TTT+S+ Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAST 1138 Query: 1300 AGSSF--VFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTA--LFPTGS 1355 GS VF T + S G+ T + A+ + G + ++STA T S Sbjct: 1139 TGSEMTTVFTTVSETTTVS-TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1197 Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415 T +S S+ S+++ S +++AF GS TT + + P+ Sbjct: 1198 TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATS 1257 Query: 1416 TFGANSSTPAASA 1428 G+ ++T + +A Sbjct: 1258 LTGSETTTVSITA 1270 Score = 85.1 bits (209), Expect = 5e-16 Identities = 157/800 (19%), Positives = 285/800 (35%), Gaps = 65/800 (8%) Query: 691 TAKQTGIETP-NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749 TA G ET + +G T + S TG +G+ ++ ET Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146 Query: 750 PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809 T T T + +ET AS++ +TT + E + VS Sbjct: 147 VSTVGSE--TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTT--VSTAGS 202 Query: 810 DNKCVSCMSEKPGSSVPASSSSTVPVSLPSG----GSLGLEKFKKPEGSWDCELCLVQNK 865 + VS + ++ A S +T ++ S + G E GS E + Sbjct: 203 ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---ETTAASTE 259 Query: 866 ADSTKCLACESAKPGTKSGFKGFDTSSSSSNSA----ASSSFKFGVSSSSSGPSQTLTST 921 T E +K T S GF+T+++S+ + AS+ +S+ GP T ST Sbjct: 260 DSETNTAFTEDSKTTTAST-TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVST 318 Query: 922 GN------FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975 + F G + V S++ +++ + +G S+ Sbjct: 319 ASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTAST 378 Query: 976 SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035 ++ + VS T + ++ E + S T +T + Sbjct: 379 EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438 Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095 + +T + S T T+ + T SE K A G L + Sbjct: 439 EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT----AYTTGSETTTASNTGLETT 494 Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK-----DENSSKST 1150 +VF +G + T+ V ++ S SE T E ++ ST Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSE------MTTVSTEGSENTTVSTTGSETTTVST 548 Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210 T S + SE +T GA+T+T + +G S +T A++AG Sbjct: 549 TGLETTTTSTEGSEMTTVSTT--GAETTTDSTEG--------------SGTTAASTAGSE 592 Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV 1270 ST+ S A+ ++++ ++ + TA +++S++ S + TT ST + Sbjct: 593 TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652 Query: 1271 TPFVFGPGA--------SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGAN 1322 T V G+ S TT S G T ++ +G++ V TG S G+ Sbjct: 653 TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-GSE 711 Query: 1323 QTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380 T T + + + G + ++ST + T S T ++ S+ S+ Sbjct: 712 TTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771 Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440 + S ++ A GS TT + ++ + VFT + ++ + +A + + ++ Sbjct: 772 TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831 Query: 1441 SPAAFTVGSNGKNVFSSSGT 1460 + A T GS S+ G+ Sbjct: 832 TIPASTAGSETTTTTSTEGS 851 Score = 79.0 bits (193), Expect = 3e-14 Identities = 193/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%) Query: 478 PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537 P S+ T + + E TT ++ A T + T+PS TGS S + T Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 68 Query: 538 NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582 + + + + TA ++GS +T+ E + S+ TT NS Sbjct: 69 STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS 128 Query: 583 TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642 T +T G E + + + S + DS + T + T Sbjct: 129 TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180 Query: 643 SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702 S + + G S+ +T + ++ + ++ + T + Sbjct: 181 GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 240 Query: 703 SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758 +TT+S +G+ T D +T +K ET T + + Sbjct: 241 GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295 Query: 759 TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810 T+ SE+ ET S++S VTT + + +GS VS + Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 352 Query: 811 NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869 S M SE S S ++T + E + S + DS Sbjct: 353 TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412 Query: 870 KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923 C T F+T+++S+ A++S + +S+ + T+T+ G+ Sbjct: 413 TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 472 Query: 924 FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979 K G + +S++G ++ + + G VS+ ++ Sbjct: 473 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532 Query: 980 NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039 N + + VS T G+ + E+ S+ G T +ST T Sbjct: 533 NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 585 Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099 ++ + + T ++++ + + +T+ A T + AS + Sbjct: 586 ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 645 Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156 + T+ + + ST+ E + V + G+ E S +T S + T Sbjct: 646 VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 703 Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208 K S SE +T G++T+T + +G+ S + S +T A++ G Sbjct: 704 KVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 759 Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265 +ST+SS +A+ + S ++S+ T + ST+ S +F+++S+ S+ Sbjct: 760 SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817 Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317 T TA + + A S TTT+ TTT+S+ GS + T S + + Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877 Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375 G+ T + + + G + ++ST + T S T + S+ Sbjct: 878 TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937 Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435 + S+ S T + + GS TT + + T G+ ++T + + + + Sbjct: 938 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 997 Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460 +++ + GS V S++GT Sbjct: 998 IEGSETTTVSSTGSETTTV-STTGT 1021 Score = 74.3 bits (181), Expect = 8e-13 Identities = 188/936 (20%), Positives = 323/936 (34%), Gaps = 102/936 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTE--- 536 T S + T + E TT S + ++ T ++ T+ S+ GS M S+ ++T Sbjct: 519 TGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST 578 Query: 537 --ANVLPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDC 593 + S+ G T +V A + + S++ E +S+ TT ST +T Sbjct: 579 EGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAST 638 Query: 594 EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSS----G 649 EG + S ++ + G + I S T T + +S+ S Sbjct: 639 EGS-ETTTVSTTDSETTMVSTTG-SERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696 Query: 650 IGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTT 707 I E+ K ++ T T+ I + S TA G ET S G T Sbjct: 697 ITGSETTKVSTTGSETT----TTSTEGSEITTASITGSETTTASTEGSETTTASTEGSET 752 Query: 708 LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767 SAS TG + ++ ++ + ET K T + T V +E++ Sbjct: 753 TSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT--VFTENS 810 Query: 768 ETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPA 827 ET AS+++ TT + + E + + +E + SE +S + Sbjct: 811 ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTES 870 Query: 828 SSSSTVPVSLPSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886 S ++T ++G E EGS E + T + E ++ T S Sbjct: 871 SETTTAT-------TIGSETTTASTEGS---ETTTTSTEGSETTTASTEGSEITTVS--- 917 Query: 887 GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS---SDSGSI 943 ++ S + AS+ ++S+ G T ST G I VS S++ ++ Sbjct: 918 ----TTGSETTTASTEGSETTTASTEGSELTTVST-------TGSETITVSAEGSETTTV 966 Query: 944 NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVS 1003 M + G VS+ ++ + + VS T + ++ Sbjct: 967 TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTIT 1026 Query: 1004 NLGQEEKKEELPKSSSAGFSFGTG---VINSTPAPANTIVTSENKSSFNLGTIETKSASV 1060 + E S + TG ST T V++ + T + ++ +V Sbjct: 1027 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTV 1086 Query: 1061 APFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS---LV 1117 + T+ A T + AS + + T + T+ S V Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146 Query: 1118 FGKKADNEEPKC----QPVFSFGNSEQTK-----DENSSKSTFSFSMTKPSEKESEQPAK 1168 F ++ S SE T E ++ ST T S SE Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTA 1206 Query: 1169 ATFAF--------GAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSN 1220 +T G++TST + G+ + + ++ +ST +S Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAST---------------ASL 1251 Query: 1221 PPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGAS 1280 P AT + G + VS +A G TA S+T S F T +T ++ P P + Sbjct: 1252 EPTATSLTGSETTTVSITASGATAASTTVSSTTF------VLTKATDVSIQPITNTPMSG 1305 Query: 1281 SNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPG 1340 + T G T +SS + + T +A P N + + GAS Sbjct: 1306 TRTT-----GTRPTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAH 1360 Query: 1341 FGSISSSTALFPTGS---QPAPPTFG--TVSSSSQP 1371 ++ + PT S + P + G TVS S P Sbjct: 1361 GVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTP 1396 Score = 54.7 bits (130), Expect = 7e-07 Identities = 165/869 (18%), Positives = 302/869 (34%), Gaps = 104/869 (11%) Query: 476 SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535 S T S T + +S E TT+S ++ T + T S+TGS S+ ++T Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674 Query: 536 -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586 E V S T S+ ++T ++S GS +T S+ +TT + T Sbjct: 675 TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---TTSTEGSEITTASITG-S 730 Query: 587 KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646 +T EG EGS + G ++ A T++ + + + Sbjct: 731 ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 784 Query: 647 SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706 +S IG + + +S + T +N ++ + A++ + TA I +T Sbjct: 785 ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 842 Query: 707 TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766 T + S G G+ ++ + ET T + + T T +E Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 900 Query: 767 AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 +ET TAS+ +TT + + S + S + ++V Sbjct: 901 SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 947 Query: 827 ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886 + S T+ VS EGS + + ++ + E+ T Sbjct: 948 TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993 Query: 887 GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946 + S + SS+ + S++G T+TST G + S++ ++ Sbjct: 994 TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAV--- 1046 Query: 947 SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006 + SE+ + G + ++ L S G Sbjct: 1047 --------------YTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066 ++++ + TG +T + + T+ + +S T T + + Sbjct: 1093 TTTASTAGSETTTV---YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149 Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126 SE T + G+ S + S TE + T+T+ G + Sbjct: 1150 VSE--------TTTVSTIGSEATTSSAAGSEATTTSTEGSE----TTTASTAGSETTTAS 1197 Query: 1127 PKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAA 1186 + S E ++ T + PS SE F G++T T A + Sbjct: 1198 TAGSETTTASTS---GSETNTACTTGSETSTPSSAGSE--TNTAFIIGSET-TIASTASL 1251 Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF------ 1240 +P + L + S ++T + +A G S+T SS V T S P++++ Sbjct: 1252 EPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1309 Query: 1241 GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTSS 1298 G +S+S ++ D + S T + G G S+ ++TTS G TT S+ Sbjct: 1310 GTRPTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369 Query: 1299 SAGSSFVF-GTGPSAPSASPAFGANQTPT 1326 +S F TGP + + + TPT Sbjct: 1370 REPTSSTFQETGPVSMGTN-TVSMSHTPT 1397 Score = 41.6 bits (96), Expect = 0.006 Identities = 50/197 (25%), Positives = 80/197 (40%), Gaps = 29/197 (14%) Query: 1277 PGASSNNTTTSGFGF---------GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327 P A SN TT S G TTT+S+AGS T PS + + Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET---TTPSPTGSQTTIVSISGSEI 65 Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ-SAFGSG 1386 + A N + S +T GS+ T G S ++ + G + + SA GS Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG--SETTTVSITGTETTMVSAMGSE 123 Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446 TT NS+++ S TT + + + V T G+ ++T + +++ AA T Sbjct: 124 TTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYTAD----------SETTAAST 169 Query: 1447 VGSNGKNVFSSSGTSFS 1463 GS VF++ + + Sbjct: 170 TGSEMTTVFTAGSETIT 186 >gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] Length = 1704 Score = 99.4 bits (246), Expect = 2e-20 Identities = 207/1055 (19%), Positives = 376/1055 (35%), Gaps = 112/1055 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 TSS + + E TT S ++ A T + T+ S+TGS M + + + + Sbjct: 130 TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM----TTVFTAGSETI 185 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599 P ++ T +V A + + S++ E +S+AH TT ST +T G Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245 Query: 600 AE------------------ILKEGSVLDILKSPGFASPKIDSVAAQPTATS-------- 633 E S + GF + + ++PT S Sbjct: 246 VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTM 305 Query: 634 -----PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-- 686 P SS ++ G S+ +T + ++ + ++ Sbjct: 306 ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365 Query: 687 -----SPRDTAKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEA 739 S TA G ET S G + S TG + + TC ++ A Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425 Query: 740 IKCVACETPKPGT------------------CVKRALTLTVVSESAETMTA-SSSSCTVT 780 + ET T + + T TV + +ET TA ++ S T T Sbjct: 426 VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485 Query: 781 TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS--- 836 G IGS S + VS SE S S ++TV + Sbjct: 486 ASNTGLETTTVFTIGS---DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSE 542 Query: 837 LPSGGSLGLE-KFKKPEGS-------WDCELCLVQNKADSTKCLACESAKPGTKSGFKGF 888 + + GLE EGS E + T + ++ T S Sbjct: 543 TTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSE 602 Query: 889 DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE 948 +T++S+++S +S+ G ++++ + + T+T + + G + S++ ++ Sbjct: 603 NTTASTADSETTSASTTGSETTTASTTSSETTTASTE-GSETTTVSTTDSETTMVSTTGS 661 Query: 949 GFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQE 1008 + G VS+ V + ++ + VS T G Sbjct: 662 ERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTT----GSETTTTS 716 Query: 1009 EKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTS 1068 + E+ +S G T + + SE S+ G+ T +++ + T S Sbjct: 717 TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776 Query: 1069 EAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPK 1128 E A+ G V AS +VF E + + ST+ + Sbjct: 777 IMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAGSE 831 Query: 1129 CQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTADQG 1184 P + G+ + T E S +T S S T + ES + AT G++T+T + +G Sbjct: 832 TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTASTEG 890 Query: 1185 AAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTA 1244 + S + S +T A++ G I ST+ S A+ +++ + + T Sbjct: 891 SETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTV 946 Query: 1245 ESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-- 1302 ++ S+++ S + TT +T + T G+ + +T+G TTT+S GS Sbjct: 947 STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGSET 1003 Query: 1303 SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF 1362 + V TG + S G T T + + G S +TA++ TGS+ T Sbjct: 1004 TTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE----TT 1054 Query: 1363 GTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS 1422 T + S+ S++ S +++ GS TT + + + V+ G+ ++ Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114 Query: 1423 TPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457 T + + + +++ A T GS VF++ Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149 Score = 95.1 bits (235), Expect = 4e-19 Identities = 206/1019 (20%), Positives = 385/1019 (37%), Gaps = 104/1019 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T++S F ++ T S P+ ++ + T P +T V + + Sbjct: 274 TTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET 333 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599 + S++G + T +GS +T I+ S T+ +ST +T EG Sbjct: 334 IRASTVGSETT-----TVSTTGSETTTASIMGSE----TSTDSTTGSETTTASTEGS-ET 383 Query: 600 AEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF-----SSSGIGFGE 654 EGS + + G + + ++ T T A+S+ ++S G Sbjct: 384 TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443 Query: 655 SLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-----SPRDTAKQTGIETPN--KSGKTT 707 ++ + S + T + T A K S TA TG+ET G T Sbjct: 444 TIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDT 503 Query: 708 LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767 +AS G G+ ++ + ET T T T +E + Sbjct: 504 TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLE--TTTTSTEGS 561 Query: 768 ETMTASSSSCTVTT-GTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 E T S++ TT T G G GS +V ++E+ + SE +S Sbjct: 562 EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA--DSENTTASTADSETTSASTT 619 Query: 827 ASSSSTVPVSLPSGGSLGLEKFKKPEGSW-DCELCLVQNKADSTKCLACESAKPGTKSGF 885 S ++T + + E + S D E +V + E ++ T S Sbjct: 620 GSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSA- 678 Query: 886 KGFDTSSSSSNSAASSSFKFGVSS---SSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGS 942 G +T+ S+ S ++ G + S++G T TST G +I +S +GS Sbjct: 679 TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTE--------GSEITTASITGS 730 Query: 943 --INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQF 1000 +EG + + + S+ + E S + + ++S + + ++ Sbjct: 731 ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSS-ETTMASIMGSETTMA---- 785 Query: 1001 GVSNLGQEEKKEELPKSSSAGF---SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS 1057 S +G E K S + T + ++T + T+ T+ ++ TI + Sbjct: 786 --STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE------TIPAST 837 Query: 1058 ASVAPFTCKTSEAKKEEMPATKGG-FSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSL 1116 A T ++E + +T+G + + E + +A+ T + T+T+ Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897 Query: 1117 VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQ 1176 G + + + + T E ++ ST T S + SE +T G++ Sbjct: 898 TEGSETTTASTEGSEITTVST---TGSETTTASTEGSETTTASTEGSELTTVSTT--GSE 952 Query: 1177 TSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVS 1236 T T + +G+ + + S +T A++AG ST+ S A+ + G + VS Sbjct: 953 TITVSAEGSETTTVTTMG----SETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVS 1007 Query: 1237 SSAFGNTAESST-SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATT 1295 S+ T S+T +++ + S + TT +T + T V+ G+ + T+T G TT Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG---SETT 1064 Query: 1296 TSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGS 1355 T S+ GS + A A+ T + G+ GS +T ++ TGS Sbjct: 1065 TVSTTGSE-----------TTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGS 1111 Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415 + T ++S++ S++ S T+ +++A GS T T + + V Sbjct: 1112 K-------TTTASTEG-------SEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVS 1157 Query: 1416 TFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSG----TSFSGRKIKTA 1470 T G+ ++T +A+ + + +++ A T GS ++ S SG + TA Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTA 1216 Score = 86.7 bits (213), Expect = 2e-16 Identities = 186/973 (19%), Positives = 359/973 (36%), Gaps = 75/973 (7%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T S T + E +T S + ++ A T + T+ S+ GS S+ ++T ++ Sbjct: 349 TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598 + + + +E++ S+T+ E +S+ T+ ST+ +T EG Sbjct: 409 TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 462 Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658 + GS + G + + + T V+T I S +++ G A Sbjct: 463 TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 515 Query: 659 GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716 S+ + + + ++N ++ ++ + T TG+ET S G + S TG Sbjct: 516 VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 572 Query: 717 DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776 G+ ++ + E T T + + +ET TAS++S Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 630 Query: 777 CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836 TT + GS +V + ++E + SE+ +S S ++TV + Sbjct: 631 SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 679 Query: 837 LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896 G E EGS + + ++ E+ T+ + + S Sbjct: 680 -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732 Query: 897 SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956 + AS+ ++S+ G T ST G + SS++ + M + I Sbjct: 733 TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 788 Query: 957 GDFKFGVSS-ESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELP 1015 G VS+ SK V ++ +S + + S G E Sbjct: 789 GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT--- 845 Query: 1016 KSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEM 1075 +S+ G T + + +SE ++ +G+ T +++ T TS E Sbjct: 846 -TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904 Query: 1076 PATKGGFSFGNVEPASLPSASVFVLGR------TEEKQQEPVTST-SLVFGKKADNEEPK 1128 A+ G V + + G TE + V++T S A+ E Sbjct: 905 TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964 Query: 1129 CQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATF--AFGAQTSTTADQGAA 1186 V + G+ T S++T + + S + ++ T + G++T+T + G Sbjct: 965 T--VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1022 Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246 + S + S +T T+AG T+ S + +++ ++ + TA + Sbjct: 1023 TTITS----TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078 Query: 1247 STSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSG-------FGFGATTTSSS 1299 + ++ S TT+ST + T V+ G+ + +T G TTT+S+ Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAST 1138 Query: 1300 AGSSF--VFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTA--LFPTGS 1355 GS VF T + S G+ T + A+ + G + ++STA T S Sbjct: 1139 TGSEMTTVFTTVSETTTVS-TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1197 Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415 T +S S+ S+++ S +++AF GS TT + + P+ Sbjct: 1198 TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATS 1257 Query: 1416 TFGANSSTPAASA 1428 G+ ++T + +A Sbjct: 1258 LTGSETTTVSITA 1270 Score = 85.1 bits (209), Expect = 5e-16 Identities = 157/800 (19%), Positives = 285/800 (35%), Gaps = 65/800 (8%) Query: 691 TAKQTGIETP-NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749 TA G ET + +G T + S TG +G+ ++ ET Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146 Query: 750 PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809 T T T + +ET AS++ +TT + E + VS Sbjct: 147 VSTVGSE--TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTT--VSTAGS 202 Query: 810 DNKCVSCMSEKPGSSVPASSSSTVPVSLPSG----GSLGLEKFKKPEGSWDCELCLVQNK 865 + VS + ++ A S +T ++ S + G E GS E + Sbjct: 203 ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---ETTAASTE 259 Query: 866 ADSTKCLACESAKPGTKSGFKGFDTSSSSSNSA----ASSSFKFGVSSSSSGPSQTLTST 921 T E +K T S GF+T+++S+ + AS+ +S+ GP T ST Sbjct: 260 DSETNTAFTEDSKTTTAST-TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVST 318 Query: 922 GN------FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975 + F G + V S++ +++ + +G S+ Sbjct: 319 ASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTAST 378 Query: 976 SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035 ++ + VS T + ++ E + S T +T + Sbjct: 379 EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438 Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095 + +T + S T T+ + T SE K A G L + Sbjct: 439 EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT----AYTTGSETTTASNTGLETT 494 Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK-----DENSSKST 1150 +VF +G + T+ V ++ S SE T E ++ ST Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSE------MTTVSTEGSENTTVSTTGSETTTVST 548 Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210 T S + SE +T GA+T+T + +G S +T A++AG Sbjct: 549 TGLETTTTSTEGSEMTTVSTT--GAETTTDSTEG--------------SGTTAASTAGSE 592 Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV 1270 ST+ S A+ ++++ ++ + TA +++S++ S + TT ST + Sbjct: 593 TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652 Query: 1271 TPFVFGPGA--------SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGAN 1322 T V G+ S TT S G T ++ +G++ V TG S G+ Sbjct: 653 TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-GSE 711 Query: 1323 QTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380 T T + + + G + ++ST + T S T ++ S+ S+ Sbjct: 712 TTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771 Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440 + S ++ A GS TT + ++ + VFT + ++ + +A + + ++ Sbjct: 772 TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831 Query: 1441 SPAAFTVGSNGKNVFSSSGT 1460 + A T GS S+ G+ Sbjct: 832 TIPASTAGSETTTTTSTEGS 851 Score = 79.0 bits (193), Expect = 3e-14 Identities = 193/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%) Query: 478 PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537 P S+ T + + E TT ++ A T + T+PS TGS S + T Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 68 Query: 538 NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582 + + + + TA ++GS +T+ E + S+ TT NS Sbjct: 69 STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS 128 Query: 583 TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642 T +T G E + + + S + DS + T + T Sbjct: 129 TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180 Query: 643 SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702 S + + G S+ +T + ++ + ++ + T + Sbjct: 181 GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 240 Query: 703 SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758 +TT+S +G+ T D +T +K ET T + + Sbjct: 241 GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295 Query: 759 TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810 T+ SE+ ET S++S VTT + + +GS VS + Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 352 Query: 811 NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869 S M SE S S ++T + E + S + DS Sbjct: 353 TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412 Query: 870 KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923 C T F+T+++S+ A++S + +S+ + T+T+ G+ Sbjct: 413 TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 472 Query: 924 FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979 K G + +S++G ++ + + G VS+ ++ Sbjct: 473 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532 Query: 980 NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039 N + + VS T G+ + E+ S+ G T +ST T Sbjct: 533 NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 585 Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099 ++ + + T ++++ + + +T+ A T + AS + Sbjct: 586 ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 645 Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156 + T+ + + ST+ E + V + G+ E S +T S + T Sbjct: 646 VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 703 Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208 K S SE +T G++T+T + +G+ S + S +T A++ G Sbjct: 704 KVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 759 Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265 +ST+SS +A+ + S ++S+ T + ST+ S +F+++S+ S+ Sbjct: 760 SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817 Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317 T TA + + A S TTT+ TTT+S+ GS + T S + + Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877 Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375 G+ T + + + G + ++ST + T S T + S+ Sbjct: 878 TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937 Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435 + S+ S T + + GS TT + + T G+ ++T + + + + Sbjct: 938 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 997 Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460 +++ + GS V S++GT Sbjct: 998 IEGSETTTVSSTGSETTTV-STTGT 1021 Score = 74.3 bits (181), Expect = 8e-13 Identities = 188/936 (20%), Positives = 323/936 (34%), Gaps = 102/936 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTE--- 536 T S + T + E TT S + ++ T ++ T+ S+ GS M S+ ++T Sbjct: 519 TGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST 578 Query: 537 --ANVLPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDC 593 + S+ G T +V A + + S++ E +S+ TT ST +T Sbjct: 579 EGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAST 638 Query: 594 EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSS----G 649 EG + S ++ + G + I S T T + +S+ S Sbjct: 639 EGS-ETTTVSTTDSETTMVSTTG-SERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696 Query: 650 IGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTT 707 I E+ K ++ T T+ I + S TA G ET S G T Sbjct: 697 ITGSETTKVSTTGSETT----TTSTEGSEITTASITGSETTTASTEGSETTTASTEGSET 752 Query: 708 LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767 SAS TG + ++ ++ + ET K T + T V +E++ Sbjct: 753 TSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT--VFTENS 810 Query: 768 ETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPA 827 ET AS+++ TT + + E + + +E + SE +S + Sbjct: 811 ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTES 870 Query: 828 SSSSTVPVSLPSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886 S ++T ++G E EGS E + T + E ++ T S Sbjct: 871 SETTTAT-------TIGSETTTASTEGS---ETTTTSTEGSETTTASTEGSEITTVS--- 917 Query: 887 GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS---SDSGSI 943 ++ S + AS+ ++S+ G T ST G I VS S++ ++ Sbjct: 918 ----TTGSETTTASTEGSETTTASTEGSELTTVST-------TGSETITVSAEGSETTTV 966 Query: 944 NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVS 1003 M + G VS+ ++ + + VS T + ++ Sbjct: 967 TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTIT 1026 Query: 1004 NLGQEEKKEELPKSSSAGFSFGTG---VINSTPAPANTIVTSENKSSFNLGTIETKSASV 1060 + E S + TG ST T V++ + T + ++ +V Sbjct: 1027 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTV 1086 Query: 1061 APFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS---LV 1117 + T+ A T + AS + + T + T+ S V Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146 Query: 1118 FGKKADNEEPKC----QPVFSFGNSEQTK-----DENSSKSTFSFSMTKPSEKESEQPAK 1168 F ++ S SE T E ++ ST T S SE Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTA 1206 Query: 1169 ATFAF--------GAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSN 1220 +T G++TST + G+ + + ++ +ST +S Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAST---------------ASL 1251 Query: 1221 PPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGAS 1280 P AT + G + VS +A G TA S+T S F T +T ++ P P + Sbjct: 1252 EPTATSLTGSETTTVSITASGATAASTTVSSTTF------VLTKATDVSIQPITNTPMSG 1305 Query: 1281 SNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPG 1340 + T G T +SS + + T +A P N + + GAS Sbjct: 1306 TRTT-----GTRPTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAH 1360 Query: 1341 FGSISSSTALFPTGS---QPAPPTFG--TVSSSSQP 1371 ++ + PT S + P + G TVS S P Sbjct: 1361 GVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTP 1396 Score = 54.7 bits (130), Expect = 7e-07 Identities = 165/869 (18%), Positives = 302/869 (34%), Gaps = 104/869 (11%) Query: 476 SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535 S T S T + +S E TT+S ++ T + T S+TGS S+ ++T Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674 Query: 536 -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586 E V S T S+ ++T ++S GS +T S+ +TT + T Sbjct: 675 TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---TTSTEGSEITTASITG-S 730 Query: 587 KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646 +T EG EGS + G ++ A T++ + + + Sbjct: 731 ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 784 Query: 647 SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706 +S IG + + +S + T +N ++ + A++ + TA I +T Sbjct: 785 ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 842 Query: 707 TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766 T + S G G+ ++ + ET T + + T T +E Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 900 Query: 767 AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 +ET TAS+ +TT + + S + S + ++V Sbjct: 901 SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 947 Query: 827 ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886 + S T+ VS EGS + + ++ + E+ T Sbjct: 948 TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993 Query: 887 GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946 + S + SS+ + S++G T+TST G + S++ ++ Sbjct: 994 TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAV--- 1046 Query: 947 SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006 + SE+ + G + ++ L S G Sbjct: 1047 --------------YTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066 ++++ + TG +T + + T+ + +S T T + + Sbjct: 1093 TTTASTAGSETTTV---YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149 Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126 SE T + G+ S + S TE + T+T+ G + Sbjct: 1150 VSE--------TTTVSTIGSEATTSSAAGSEATTTSTEGSE----TTTASTAGSETTTAS 1197 Query: 1127 PKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAA 1186 + S E ++ T + PS SE F G++T T A + Sbjct: 1198 TAGSETTTASTS---GSETNTACTTGSETSTPSSAGSE--TNTAFIIGSET-TIASTASL 1251 Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF------ 1240 +P + L + S ++T + +A G S+T SS V T S P++++ Sbjct: 1252 EPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1309 Query: 1241 GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTSS 1298 G +S+S ++ D + S T + G G S+ ++TTS G TT S+ Sbjct: 1310 GTRPTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369 Query: 1299 SAGSSFVF-GTGPSAPSASPAFGANQTPT 1326 +S F TGP + + + TPT Sbjct: 1370 REPTSSTFQETGPVSMGTN-TVSMSHTPT 1397 Score = 41.6 bits (96), Expect = 0.006 Identities = 50/197 (25%), Positives = 80/197 (40%), Gaps = 29/197 (14%) Query: 1277 PGASSNNTTTSGFGF---------GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327 P A SN TT S G TTT+S+AGS T PS + + Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET---TTPSPTGSQTTIVSISGSEI 65 Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ-SAFGSG 1386 + A N + S +T GS+ T G S ++ + G + + SA GS Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG--SETTTVSITGTETTMVSAMGSE 123 Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446 TT NS+++ S TT + + + V T G+ ++T + +++ AA T Sbjct: 124 TTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYTAD----------SETTAAST 169 Query: 1447 VGSNGKNVFSSSGTSFS 1463 GS VF++ + + Sbjct: 170 TGSEMTTVFTAGSETIT 186 >gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 99.4 bits (246), Expect = 2e-20 Identities = 216/1057 (20%), Positives = 377/1057 (35%), Gaps = 116/1057 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 TSS + + E TT S ++ A T + T+ S+TGS M V + + Sbjct: 130 TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM-----TTVFTAGSET 184 Query: 540 LPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598 + PS+ G T +V A + + S++ E +S+AH TT ST +T G Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244 Query: 599 PAEI------------------LKEGSVLDILKSPGFASPKIDSVAAQPTATS------- 633 E S + GF + + ++PT S Sbjct: 245 TVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETT 304 Query: 634 ------PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLS 687 P SS ++ G S+ +T + ++ + ++ S Sbjct: 305 MASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETS 364 Query: 688 PRDT-------AKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPE 738 T A G ET S G + S TG + + TC ++ Sbjct: 365 TDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMT 424 Query: 739 AIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWE 798 A+ ET T +T+ S+S T ++ S T T T G K GS Sbjct: 425 AVSTTVFETTTAST-EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSET 483 Query: 799 CSVC-----------------CVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS---L 837 + S + VS SE S S ++TV + Sbjct: 484 TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543 Query: 838 PSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSS---- 892 + + GLE EGS E+ V T + E + T + G +T++ Sbjct: 544 TTVSTTGLETTTTSTEGS---EMTTVSTTGAETTTDSTEGSGT-TAASTAGSETTTVSTA 599 Query: 893 SSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKF---GDQGGFKIGVS---SDSGSINPM 946 S N+ AS++ S+S++G T ST + + +G VS S++ ++ Sbjct: 600 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659 Query: 947 SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006 + G VS+ V + ++ + VS T G Sbjct: 660 GSERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTT----GSETTT 714 Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066 + E+ +S G T + + SE S+ G+ T +++ + T Sbjct: 715 TSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTM 774 Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126 S E A+ G V AS +VF E + + ST+ Sbjct: 775 ASIMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAG 829 Query: 1127 PKCQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTAD 1182 + P + G+ + T E S +T S S T + ES + AT G++T+T + Sbjct: 830 SETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTAST 888 Query: 1183 QGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGN 1242 +G+ S + S +T A++ G I ST+ S A+ +++ + + Sbjct: 889 EGSETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELT 944 Query: 1243 TAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS 1302 T ++ S+++ S + TT +T + T G+ + +T+G TTT+S GS Sbjct: 945 TVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGS 1001 Query: 1303 --SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPP 1360 + V TG + S G T T + + G S +TA++ TGS+ Sbjct: 1002 ETTTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE---- 1052 Query: 1361 TFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGAN 1420 T T + S+ S++ S +++ GS TT + + + V+ G+ Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112 Query: 1421 SSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457 ++T + + + +++ A T GS VF++ Sbjct: 1113 TTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149 Score = 94.4 bits (233), Expect = 7e-19 Identities = 201/994 (20%), Positives = 377/994 (37%), Gaps = 100/994 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T++S F ++ T S P+ ++ + T P +T V + + Sbjct: 274 TTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET 333 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599 + S++G + T +GS +T I+ S T+ +ST +T EG Sbjct: 334 IRASTVGSETT-----TVSTTGSETTTASIMGSE----TSTDSTTGSETTTASTEGS-ET 383 Query: 600 AEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF-----SSSGIGFGE 654 EGS + + G + + ++ T T A+S+ ++S G Sbjct: 384 TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443 Query: 655 SLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-----SPRDTAKQTGIETPN--KSGKTT 707 ++ + S + T + T A K S TA TG+ET G T Sbjct: 444 TIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDT 503 Query: 708 LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767 +AS G G+ ++ + ET T T T +E + Sbjct: 504 TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLE--TTTTSTEGS 561 Query: 768 ETMTASSSSCTVTT-GTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 E T S++ TT T G G GS +V ++E+ + SE +S Sbjct: 562 EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA--DSENTTASTADSETTSASTT 619 Query: 827 ASSSSTVPVSLPSGGSLGLEKFKKPEGSW-DCELCLVQNKADSTKCLACESAKPGTKSGF 885 S ++T + + E + S D E +V + E ++ T S Sbjct: 620 GSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSA- 678 Query: 886 KGFDTSSSSSNSAASSSFKFGVSS---SSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGS 942 G +T+ S+ S ++ G + S++G T TST G +I +S +GS Sbjct: 679 TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTE--------GSEITTASITGS 730 Query: 943 --INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQF 1000 +EG + + + S+ + E S + + ++S + + ++ Sbjct: 731 ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSS-ETTMASIMGSETTMA---- 785 Query: 1001 GVSNLGQEEKKEELPKSSSAGF---SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS 1057 S +G E K S + T + ++T + T+ T+ ++ TI + Sbjct: 786 --STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE------TIPAST 837 Query: 1058 ASVAPFTCKTSEAKKEEMPATKGG-FSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSL 1116 A T ++E + +T+G + + E + +A+ T + T+T+ Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897 Query: 1117 VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQ 1176 G + + + + T E ++ ST T S + SE +T G++ Sbjct: 898 TEGSETTTASTEGSEITTVST---TGSETTTASTEGSETTTASTEGSELTTVSTT--GSE 952 Query: 1177 TSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVS 1236 T T + +G+ + + S +T A++AG ST+ S A+ + G + VS Sbjct: 953 TITVSAEGSETTTVTTMG----SETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVS 1007 Query: 1237 SSAFGNTAESST-SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATT 1295 S+ T S+T +++ + S + TT +T + T V+ G+ + T+T G TT Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG---SETT 1064 Query: 1296 TSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGS 1355 T S+ GS + A A+ T + G+ GS +T ++ TGS Sbjct: 1065 TVSTTGSE-----------TTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGS 1111 Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415 + T ++S++ S++ S T+ +++A GS T T + + V Sbjct: 1112 K-------TTTASTEG-------SEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVS 1157 Query: 1416 TFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGS 1449 T G+ ++T +A+ + + +++ A T GS Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAGS 1191 Score = 88.6 bits (218), Expect = 4e-17 Identities = 188/993 (18%), Positives = 361/993 (36%), Gaps = 105/993 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T S T + E +T S + ++ A T + T+ S+ GS S+ ++T ++ Sbjct: 349 TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598 + + + +E++ S+T+ E +S+ T+ ST+ +T EG Sbjct: 409 TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 462 Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658 + GS + G + + + T V+T I S +++ G A Sbjct: 463 TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 515 Query: 659 GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716 S+ + + + ++N ++ ++ + T TG+ET S G + S TG Sbjct: 516 VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 572 Query: 717 DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776 G+ ++ + E T T + + +ET TAS++S Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 630 Query: 777 CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836 TT + GS +V + ++E + SE+ +S S ++TV + Sbjct: 631 SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 679 Query: 837 LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896 G E EGS + + ++ E+ T+ + + S Sbjct: 680 -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732 Query: 897 SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956 + AS+ ++S+ G T ST G + SS++ + M + I Sbjct: 733 TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 788 Query: 957 GDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPK 1016 G VS+ S +N + ++S ++ + VS G E +P Sbjct: 789 GSETTKVSTASSKMTTVF---TENSETTIASTTASETTT------VSTAGSET----IPA 835 Query: 1017 SSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMP 1076 S++ T ST T ++E + T +++ + +T+ A E Sbjct: 836 STAGS---ETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSE 892 Query: 1077 ATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKK---ADNEEPKCQPVF 1133 T AS + + + T + T+T+ G + A E + V Sbjct: 893 TTTTSTEGSETTTASTEGSEITTVSTTGSE-----TTTASTEGSETTTASTEGSELTTVS 947 Query: 1134 SFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAF--GAQTSTTADQGAAKPVFS 1191 + G+ T S++T +M + S ++ T G++T+T + +G+ S Sbjct: 948 TTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVS 1007 Query: 1192 FLNN-----SSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246 + S++ + T TS G + T++ + A + G + S+ T S Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVS 1067 Query: 1247 STSQSLLFSQDSKL-----------ATTSSTGTAVTPFVFGPGA---------------- 1279 +T + + L TT+ST + T V+ G+ Sbjct: 1068 TTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127 Query: 1280 --SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPN 1337 SS TT S G TT ++ + T S + S A G+ T T + + + Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS 1187 Query: 1338 PPGFGSISSSTA--LFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAF 1395 G + ++STA T S T +S S+ S+++ S +++AF Sbjct: 1188 TAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAF 1247 Query: 1396 QFGSSTTNFNFTNNSPSGVFTFGANSSTPAASA 1428 GS TT + + P+ G+ ++T + +A Sbjct: 1248 IIGSETTIASTASLEPTATSLTGSETTTVSITA 1280 Score = 85.1 bits (209), Expect = 5e-16 Identities = 157/800 (19%), Positives = 285/800 (35%), Gaps = 65/800 (8%) Query: 691 TAKQTGIETP-NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749 TA G ET + +G T + S TG +G+ ++ ET Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146 Query: 750 PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809 T T T + +ET AS++ +TT + E + VS Sbjct: 147 VSTVGSE--TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTT--VSTAGS 202 Query: 810 DNKCVSCMSEKPGSSVPASSSSTVPVSLPSG----GSLGLEKFKKPEGSWDCELCLVQNK 865 + VS + ++ A S +T ++ S + G E GS E + Sbjct: 203 ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---ETTAASTE 259 Query: 866 ADSTKCLACESAKPGTKSGFKGFDTSSSSSNSA----ASSSFKFGVSSSSSGPSQTLTST 921 T E +K T S GF+T+++S+ + AS+ +S+ GP T ST Sbjct: 260 DSETNTAFTEDSKTTTAST-TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVST 318 Query: 922 GN------FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975 + F G + V S++ +++ + +G S+ Sbjct: 319 ASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTAST 378 Query: 976 SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035 ++ + VS T + ++ E + S T +T + Sbjct: 379 EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438 Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095 + +T + S T T+ + T SE K A G L + Sbjct: 439 EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT----AYTTGSETTTASNTGLETT 494 Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK-----DENSSKST 1150 +VF +G + T+ V ++ S SE T E ++ ST Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSE------MTTVSTEGSENTTVSTTGSETTTVST 548 Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210 T S + SE +T GA+T+T + +G S +T A++AG Sbjct: 549 TGLETTTTSTEGSEMTTVSTT--GAETTTDSTEG--------------SGTTAASTAGSE 592 Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV 1270 ST+ S A+ ++++ ++ + TA +++S++ S + TT ST + Sbjct: 593 TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652 Query: 1271 TPFVFGPGA--------SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGAN 1322 T V G+ S TT S G T ++ +G++ V TG S G+ Sbjct: 653 TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-GSE 711 Query: 1323 QTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380 T T + + + G + ++ST + T S T ++ S+ S+ Sbjct: 712 TTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771 Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440 + S ++ A GS TT + ++ + VFT + ++ + +A + + ++ Sbjct: 772 TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831 Query: 1441 SPAAFTVGSNGKNVFSSSGT 1460 + A T GS S+ G+ Sbjct: 832 TIPASTAGSETTTTTSTEGS 851 Score = 79.3 bits (194), Expect = 2e-14 Identities = 219/1063 (20%), Positives = 383/1063 (36%), Gaps = 157/1063 (14%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T S T + + E TT+ + T + T+ S+ GS + S+ ++T A+ Sbjct: 399 TGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTAST 458 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSST------LEPIISSSAHHVTTVNSTNCKKTPPEDC 593 + T + KTA +GS +T LE + TT ST +T Sbjct: 459 EGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSA 518 Query: 594 EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSP-------VVYTRPAISSFS 646 G + EGS + + G + + + + T TS V T ++ S Sbjct: 519 TGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDS 577 Query: 647 SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706 + G G + AGS +T + ++N + ++ + +A TG ET S + Sbjct: 578 TEGSGTTAASTAGS----ETTTVSTADSENTTASTADSETT---SASTTGSETTTASTTS 630 Query: 707 TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766 + + + + G + + T D +T +V T +R +T T E Sbjct: 631 SETTTASTEGSE-TTTVSTTDSETTMVST----------------TGSERTITST---EG 670 Query: 767 AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSN-----NAEDNKCVSCM---S 818 +ET T S++ T T G G GS V + + E ++ + S Sbjct: 671 SETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGS 730 Query: 819 EKPGSSVPASSSSTVPVS---LPSGGSLGLEKFKKPEGSWDCELCLVQ-NKADSTKCLAC 874 E +S S ++T S + G E S + + + ++ + Sbjct: 731 ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGS 790 Query: 875 ESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSG----PSQTLTSTGNFKFGDQG 930 E+ K T S + +S + AS++ + S++G P+ T S +G Sbjct: 791 ETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEG 850 Query: 931 GFKIGVS---SDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSS 987 S S++ + + S + IG S+E ++ Sbjct: 851 SETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG 910 Query: 988 GLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVT--SENK 1045 VS T G + E +S+ G T +++T + T+ SE Sbjct: 911 SEITTVSTT----GSETTTASTEGSETTTASTEGSELTT--VSTTGSETITVSAEGSETT 964 Query: 1046 SSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGR--- 1102 + +G+ T +++ T S A E A+ G V + +V G Sbjct: 965 TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024 Query: 1103 ---TEEKQQEPVTS----TSLVFGKKADN-----EEPKCQPVFSFGNSEQTKD----ENS 1146 TE + VT+ T+ V+ ++ E + V + G+ T E + Sbjct: 1025 ITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084 Query: 1147 SKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPAT- 1205 + ST T S SE + G++T+T + +G+ S ++ ++++ST + Sbjct: 1085 TVSTSGSGTTTASTAGSE--TTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSE 1142 Query: 1206 ----------SAGGGIFGS--STSSSNPPVATFVFGQSSNPVSSSAFGN-TAESSTSQSL 1252 + GS +TSS+ AT + S ++S G+ T +ST+ S Sbjct: 1143 MTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS- 1201 Query: 1253 LFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS----SFVFG- 1307 TT+ST + T G+ +N T+G T+T SSAGS +F+ G Sbjct: 1202 -------ETTTASTAGSETTTASTSGSETNTACTTG---SETSTPSSAGSETNTAFIIGS 1251 Query: 1308 ------TGPSAPSASPAFGANQTPTFGQSQGAS---------------------QP--NP 1338 T P+A+ G+ T + GA+ QP N Sbjct: 1252 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1311 Query: 1339 PGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFG 1398 P G+ ++ T L + S P +S++ V G + S G+ T SS+ G Sbjct: 1312 PMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHG 1371 Query: 1399 SSTTNFNFTNNSPS-----GVFTFGAN----SSTPAASAQPSG 1432 TT + + S G + G N S TP +PSG Sbjct: 1372 VRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPSG 1414 Score = 79.0 bits (193), Expect = 3e-14 Identities = 193/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%) Query: 478 PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537 P S+ T + + E TT ++ A T + T+PS TGS S + T Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 68 Query: 538 NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582 + + + + TA ++GS +T+ E + S+ TT NS Sbjct: 69 STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS 128 Query: 583 TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642 T +T G E + + + S + DS + T + T Sbjct: 129 TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180 Query: 643 SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702 S + + G S+ +T + ++ + ++ + T + Sbjct: 181 GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 240 Query: 703 SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758 +TT+S +G+ T D +T +K ET T + + Sbjct: 241 GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295 Query: 759 TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810 T+ SE+ ET S++S VTT + + +GS VS + Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 352 Query: 811 NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869 S M SE S S ++T + E + S + DS Sbjct: 353 TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412 Query: 870 KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923 C T F+T+++S+ A++S + +S+ + T+T+ G+ Sbjct: 413 TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 472 Query: 924 FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979 K G + +S++G ++ + + G VS+ ++ Sbjct: 473 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532 Query: 980 NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039 N + + VS T G+ + E+ S+ G T +ST T Sbjct: 533 NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 585 Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099 ++ + + T ++++ + + +T+ A T + AS + Sbjct: 586 ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 645 Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156 + T+ + + ST+ E + V + G+ E S +T S + T Sbjct: 646 VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 703 Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208 K S SE +T G++T+T + +G+ S + S +T A++ G Sbjct: 704 KVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 759 Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265 +ST+SS +A+ + S ++S+ T + ST+ S +F+++S+ S+ Sbjct: 760 SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817 Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317 T TA + + A S TTT+ TTT+S+ GS + T S + + Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877 Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375 G+ T + + + G + ++ST + T S T + S+ Sbjct: 878 TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937 Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435 + S+ S T + + GS TT + + T G+ ++T + + + + Sbjct: 938 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 997 Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460 +++ + GS V S++GT Sbjct: 998 IEGSETTTVSSTGSETTTV-STTGT 1021 Score = 57.8 bits (138), Expect = 8e-08 Identities = 166/870 (19%), Positives = 303/870 (34%), Gaps = 96/870 (11%) Query: 476 SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535 S T S T + +S E TT+S ++ T + T S+TGS S+ ++T Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674 Query: 536 -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586 E V S T S+ ++T ++S GS +T S+ +TT + T Sbjct: 675 TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---TTSTEGSEITTASITG-S 730 Query: 587 KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646 +T EG EGS + G ++ A T++ + + + Sbjct: 731 ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 784 Query: 647 SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706 +S IG + + +S + T +N ++ + A++ + TA I +T Sbjct: 785 ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 842 Query: 707 TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766 T + S G G+ ++ + ET T + + T T +E Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 900 Query: 767 AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 +ET TAS+ +TT + + S + S + ++V Sbjct: 901 SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 947 Query: 827 ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886 + S T+ VS EGS + + ++ + E+ T Sbjct: 948 TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993 Query: 887 GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946 + S + SS+ + S++G T+TST G + S++ ++ Sbjct: 994 TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAVYTT 1049 Query: 947 SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006 + G VS+ + + S + S + + Sbjct: 1050 GSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYIT 1109 Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTI-ETKSASVAPFTC 1065 + + S A +++T + T T+ ++ + T+ ET + S Sbjct: 1110 GSKTTTASTEGSEA------TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163 Query: 1066 KTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNE 1125 TS A E T + E + +AS T T+T+ G + Sbjct: 1164 TTSSAAGSEATTT-------STEGSETTTASTAGSETTTASTAGSETTTASTAGSETT-- 1214 Query: 1126 EPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGA 1185 + + E ++ T + PS SE F G++T T A + Sbjct: 1215 -----------TASTSGSETNTACTTGSETSTPSSAGSE--TNTAFIIGSET-TIASTAS 1260 Query: 1186 AKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF----- 1240 +P + L + S ++T + +A G S+T SS V T S P++++ Sbjct: 1261 LEPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRT 1318 Query: 1241 -GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTS 1297 G +S+S ++ D + S T + G G S+ ++TTS G TT S Sbjct: 1319 TGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGS 1378 Query: 1298 SSAGSSFVF-GTGPSAPSASPAFGANQTPT 1326 + +S F TGP + + + TPT Sbjct: 1379 TREPTSSTFQETGPVSMGTN-TVSMSHTPT 1407 Score = 41.6 bits (96), Expect = 0.006 Identities = 50/197 (25%), Positives = 80/197 (40%), Gaps = 29/197 (14%) Query: 1277 PGASSNNTTTSGFGF---------GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327 P A SN TT S G TTT+S+AGS T PS + + Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET---TTPSPTGSQTTIVSISGSEI 65 Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ-SAFGSG 1386 + A N + S +T GS+ T G S ++ + G + + SA GS Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG--SETTTVSITGTETTMVSAMGSE 123 Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446 TT NS+++ S TT + + + V T G+ ++T + +++ AA T Sbjct: 124 TTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYTAD----------SETTAAST 169 Query: 1447 VGSNGKNVFSSSGTSFS 1463 GS VF++ + + Sbjct: 170 TGSEMTTVFTAGSETIT 186 >gi|239740645 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 99.4 bits (246), Expect = 2e-20 Identities = 216/1057 (20%), Positives = 377/1057 (35%), Gaps = 116/1057 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 TSS + + E TT S ++ A T + T+ S+TGS M V + + Sbjct: 130 TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM-----TTVFTAGSET 184 Query: 540 LPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598 + PS+ G T +V A + + S++ E +S+AH TT ST +T G Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244 Query: 599 PAEI------------------LKEGSVLDILKSPGFASPKIDSVAAQPTATS------- 633 E S + GF + + ++PT S Sbjct: 245 TVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETT 304 Query: 634 ------PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLS 687 P SS ++ G S+ +T + ++ + ++ S Sbjct: 305 MASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETS 364 Query: 688 PRDT-------AKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPE 738 T A G ET S G + S TG + + TC ++ Sbjct: 365 TDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMT 424 Query: 739 AIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWE 798 A+ ET T +T+ S+S T ++ S T T T G K GS Sbjct: 425 AVSTTVFETTTAST-EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSET 483 Query: 799 CSVC-----------------CVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS---L 837 + S + VS SE S S ++TV + Sbjct: 484 TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543 Query: 838 PSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSS---- 892 + + GLE EGS E+ V T + E + T + G +T++ Sbjct: 544 TTVSTTGLETTTTSTEGS---EMTTVSTTGAETTTDSTEGSGT-TAASTAGSETTTVSTA 599 Query: 893 SSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKF---GDQGGFKIGVS---SDSGSINPM 946 S N+ AS++ S+S++G T ST + + +G VS S++ ++ Sbjct: 600 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659 Query: 947 SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006 + G VS+ V + ++ + VS T G Sbjct: 660 GSERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTT----GSETTT 714 Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066 + E+ +S G T + + SE S+ G+ T +++ + T Sbjct: 715 TSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTM 774 Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126 S E A+ G V AS +VF E + + ST+ Sbjct: 775 ASIMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAG 829 Query: 1127 PKCQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTAD 1182 + P + G+ + T E S +T S S T + ES + AT G++T+T + Sbjct: 830 SETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTAST 888 Query: 1183 QGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGN 1242 +G+ S + S +T A++ G I ST+ S A+ +++ + + Sbjct: 889 EGSETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELT 944 Query: 1243 TAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS 1302 T ++ S+++ S + TT +T + T G+ + +T+G TTT+S GS Sbjct: 945 TVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGS 1001 Query: 1303 --SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPP 1360 + V TG + S G T T + + G S +TA++ TGS+ Sbjct: 1002 ETTTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE---- 1052 Query: 1361 TFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGAN 1420 T T + S+ S++ S +++ GS TT + + + V+ G+ Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112 Query: 1421 SSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457 ++T + + + +++ A T GS VF++ Sbjct: 1113 TTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149 Score = 94.4 bits (233), Expect = 7e-19 Identities = 201/994 (20%), Positives = 377/994 (37%), Gaps = 100/994 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T++S F ++ T S P+ ++ + T P +T V + + Sbjct: 274 TTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET 333 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599 + S++G + T +GS +T I+ S T+ +ST +T EG Sbjct: 334 IRASTVGSETT-----TVSTTGSETTTASIMGSE----TSTDSTTGSETTTASTEGS-ET 383 Query: 600 AEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF-----SSSGIGFGE 654 EGS + + G + + ++ T T A+S+ ++S G Sbjct: 384 TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443 Query: 655 SLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-----SPRDTAKQTGIETPN--KSGKTT 707 ++ + S + T + T A K S TA TG+ET G T Sbjct: 444 TIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDT 503 Query: 708 LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767 +AS G G+ ++ + ET T T T +E + Sbjct: 504 TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLE--TTTTSTEGS 561 Query: 768 ETMTASSSSCTVTT-GTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 E T S++ TT T G G GS +V ++E+ + SE +S Sbjct: 562 EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA--DSENTTASTADSETTSASTT 619 Query: 827 ASSSSTVPVSLPSGGSLGLEKFKKPEGSW-DCELCLVQNKADSTKCLACESAKPGTKSGF 885 S ++T + + E + S D E +V + E ++ T S Sbjct: 620 GSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSA- 678 Query: 886 KGFDTSSSSSNSAASSSFKFGVSS---SSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGS 942 G +T+ S+ S ++ G + S++G T TST G +I +S +GS Sbjct: 679 TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTE--------GSEITTASITGS 730 Query: 943 --INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQF 1000 +EG + + + S+ + E S + + ++S + + ++ Sbjct: 731 ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSS-ETTMASIMGSETTMA---- 785 Query: 1001 GVSNLGQEEKKEELPKSSSAGF---SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS 1057 S +G E K S + T + ++T + T+ T+ ++ TI + Sbjct: 786 --STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE------TIPAST 837 Query: 1058 ASVAPFTCKTSEAKKEEMPATKGG-FSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSL 1116 A T ++E + +T+G + + E + +A+ T + T+T+ Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897 Query: 1117 VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQ 1176 G + + + + T E ++ ST T S + SE +T G++ Sbjct: 898 TEGSETTTASTEGSEITTVST---TGSETTTASTEGSETTTASTEGSELTTVSTT--GSE 952 Query: 1177 TSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVS 1236 T T + +G+ + + S +T A++AG ST+ S A+ + G + VS Sbjct: 953 TITVSAEGSETTTVTTMG----SETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVS 1007 Query: 1237 SSAFGNTAESST-SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATT 1295 S+ T S+T +++ + S + TT +T + T V+ G+ + T+T G TT Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG---SETT 1064 Query: 1296 TSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGS 1355 T S+ GS + A A+ T + G+ GS +T ++ TGS Sbjct: 1065 TVSTTGSE-----------TTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGS 1111 Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415 + T ++S++ S++ S T+ +++A GS T T + + V Sbjct: 1112 K-------TTTASTEG-------SEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVS 1157 Query: 1416 TFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGS 1449 T G+ ++T +A+ + + +++ A T GS Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAGS 1191 Score = 88.6 bits (218), Expect = 4e-17 Identities = 188/993 (18%), Positives = 361/993 (36%), Gaps = 105/993 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T S T + E +T S + ++ A T + T+ S+ GS S+ ++T ++ Sbjct: 349 TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598 + + + +E++ S+T+ E +S+ T+ ST+ +T EG Sbjct: 409 TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 462 Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658 + GS + G + + + T V+T I S +++ G A Sbjct: 463 TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 515 Query: 659 GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716 S+ + + + ++N ++ ++ + T TG+ET S G + S TG Sbjct: 516 VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 572 Query: 717 DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776 G+ ++ + E T T + + +ET TAS++S Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 630 Query: 777 CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836 TT + GS +V + ++E + SE+ +S S ++TV + Sbjct: 631 SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 679 Query: 837 LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896 G E EGS + + ++ E+ T+ + + S Sbjct: 680 -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732 Query: 897 SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956 + AS+ ++S+ G T ST G + SS++ + M + I Sbjct: 733 TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 788 Query: 957 GDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPK 1016 G VS+ S +N + ++S ++ + VS G E +P Sbjct: 789 GSETTKVSTASSKMTTVF---TENSETTIASTTASETTT------VSTAGSET----IPA 835 Query: 1017 SSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMP 1076 S++ T ST T ++E + T +++ + +T+ A E Sbjct: 836 STAGS---ETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSE 892 Query: 1077 ATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKK---ADNEEPKCQPVF 1133 T AS + + + T + T+T+ G + A E + V Sbjct: 893 TTTTSTEGSETTTASTEGSEITTVSTTGSE-----TTTASTEGSETTTASTEGSELTTVS 947 Query: 1134 SFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAF--GAQTSTTADQGAAKPVFS 1191 + G+ T S++T +M + S ++ T G++T+T + +G+ S Sbjct: 948 TTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVS 1007 Query: 1192 FLNN-----SSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246 + S++ + T TS G + T++ + A + G + S+ T S Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVS 1067 Query: 1247 STSQSLLFSQDSKL-----------ATTSSTGTAVTPFVFGPGA---------------- 1279 +T + + L TT+ST + T V+ G+ Sbjct: 1068 TTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127 Query: 1280 --SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPN 1337 SS TT S G TT ++ + T S + S A G+ T T + + + Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS 1187 Query: 1338 PPGFGSISSSTA--LFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAF 1395 G + ++STA T S T +S S+ S+++ S +++AF Sbjct: 1188 TAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAF 1247 Query: 1396 QFGSSTTNFNFTNNSPSGVFTFGANSSTPAASA 1428 GS TT + + P+ G+ ++T + +A Sbjct: 1248 IIGSETTIASTASLEPTATSLTGSETTTVSITA 1280 Score = 85.1 bits (209), Expect = 5e-16 Identities = 157/800 (19%), Positives = 285/800 (35%), Gaps = 65/800 (8%) Query: 691 TAKQTGIETP-NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749 TA G ET + +G T + S TG +G+ ++ ET Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146 Query: 750 PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809 T T T + +ET AS++ +TT + E + VS Sbjct: 147 VSTVGSE--TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTT--VSTAGS 202 Query: 810 DNKCVSCMSEKPGSSVPASSSSTVPVSLPSG----GSLGLEKFKKPEGSWDCELCLVQNK 865 + VS + ++ A S +T ++ S + G E GS E + Sbjct: 203 ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---ETTAASTE 259 Query: 866 ADSTKCLACESAKPGTKSGFKGFDTSSSSSNSA----ASSSFKFGVSSSSSGPSQTLTST 921 T E +K T S GF+T+++S+ + AS+ +S+ GP T ST Sbjct: 260 DSETNTAFTEDSKTTTAST-TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVST 318 Query: 922 GN------FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975 + F G + V S++ +++ + +G S+ Sbjct: 319 ASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTAST 378 Query: 976 SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035 ++ + VS T + ++ E + S T +T + Sbjct: 379 EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438 Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095 + +T + S T T+ + T SE K A G L + Sbjct: 439 EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT----AYTTGSETTTASNTGLETT 494 Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK-----DENSSKST 1150 +VF +G + T+ V ++ S SE T E ++ ST Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSE------MTTVSTEGSENTTVSTTGSETTTVST 548 Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210 T S + SE +T GA+T+T + +G S +T A++AG Sbjct: 549 TGLETTTTSTEGSEMTTVSTT--GAETTTDSTEG--------------SGTTAASTAGSE 592 Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV 1270 ST+ S A+ ++++ ++ + TA +++S++ S + TT ST + Sbjct: 593 TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652 Query: 1271 TPFVFGPGA--------SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGAN 1322 T V G+ S TT S G T ++ +G++ V TG S G+ Sbjct: 653 TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-GSE 711 Query: 1323 QTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380 T T + + + G + ++ST + T S T ++ S+ S+ Sbjct: 712 TTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771 Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440 + S ++ A GS TT + ++ + VFT + ++ + +A + + ++ Sbjct: 772 TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831 Query: 1441 SPAAFTVGSNGKNVFSSSGT 1460 + A T GS S+ G+ Sbjct: 832 TIPASTAGSETTTTTSTEGS 851 Score = 79.3 bits (194), Expect = 2e-14 Identities = 219/1063 (20%), Positives = 383/1063 (36%), Gaps = 157/1063 (14%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T S T + + E TT+ + T + T+ S+ GS + S+ ++T A+ Sbjct: 399 TGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTAST 458 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSST------LEPIISSSAHHVTTVNSTNCKKTPPEDC 593 + T + KTA +GS +T LE + TT ST +T Sbjct: 459 EGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSA 518 Query: 594 EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSP-------VVYTRPAISSFS 646 G + EGS + + G + + + + T TS V T ++ S Sbjct: 519 TGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDS 577 Query: 647 SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706 + G G + AGS +T + ++N + ++ + +A TG ET S + Sbjct: 578 TEGSGTTAASTAGS----ETTTVSTADSENTTASTADSETT---SASTTGSETTTASTTS 630 Query: 707 TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766 + + + + G + + T D +T +V T +R +T T E Sbjct: 631 SETTTASTEGSE-TTTVSTTDSETTMVST----------------TGSERTITST---EG 670 Query: 767 AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSN-----NAEDNKCVSCM---S 818 +ET T S++ T T G G GS V + + E ++ + S Sbjct: 671 SETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGS 730 Query: 819 EKPGSSVPASSSSTVPVS---LPSGGSLGLEKFKKPEGSWDCELCLVQ-NKADSTKCLAC 874 E +S S ++T S + G E S + + + ++ + Sbjct: 731 ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGS 790 Query: 875 ESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSG----PSQTLTSTGNFKFGDQG 930 E+ K T S + +S + AS++ + S++G P+ T S +G Sbjct: 791 ETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEG 850 Query: 931 GFKIGVS---SDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSS 987 S S++ + + S + IG S+E ++ Sbjct: 851 SETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG 910 Query: 988 GLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVT--SENK 1045 VS T G + E +S+ G T +++T + T+ SE Sbjct: 911 SEITTVSTT----GSETTTASTEGSETTTASTEGSELTT--VSTTGSETITVSAEGSETT 964 Query: 1046 SSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGR--- 1102 + +G+ T +++ T S A E A+ G V + +V G Sbjct: 965 TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024 Query: 1103 ---TEEKQQEPVTS----TSLVFGKKADN-----EEPKCQPVFSFGNSEQTKD----ENS 1146 TE + VT+ T+ V+ ++ E + V + G+ T E + Sbjct: 1025 ITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084 Query: 1147 SKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPAT- 1205 + ST T S SE + G++T+T + +G+ S ++ ++++ST + Sbjct: 1085 TVSTSGSGTTTASTAGSE--TTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSE 1142 Query: 1206 ----------SAGGGIFGS--STSSSNPPVATFVFGQSSNPVSSSAFGN-TAESSTSQSL 1252 + GS +TSS+ AT + S ++S G+ T +ST+ S Sbjct: 1143 MTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS- 1201 Query: 1253 LFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS----SFVFG- 1307 TT+ST + T G+ +N T+G T+T SSAGS +F+ G Sbjct: 1202 -------ETTTASTAGSETTTASTSGSETNTACTTG---SETSTPSSAGSETNTAFIIGS 1251 Query: 1308 ------TGPSAPSASPAFGANQTPTFGQSQGAS---------------------QP--NP 1338 T P+A+ G+ T + GA+ QP N Sbjct: 1252 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1311 Query: 1339 PGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFG 1398 P G+ ++ T L + S P +S++ V G + S G+ T SS+ G Sbjct: 1312 PMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHG 1371 Query: 1399 SSTTNFNFTNNSPS-----GVFTFGAN----SSTPAASAQPSG 1432 TT + + S G + G N S TP +PSG Sbjct: 1372 VRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPSG 1414 Score = 79.0 bits (193), Expect = 3e-14 Identities = 193/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%) Query: 478 PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537 P S+ T + + E TT ++ A T + T+PS TGS S + T Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 68 Query: 538 NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582 + + + + TA ++GS +T+ E + S+ TT NS Sbjct: 69 STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS 128 Query: 583 TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642 T +T G E + + + S + DS + T + T Sbjct: 129 TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180 Query: 643 SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702 S + + G S+ +T + ++ + ++ + T + Sbjct: 181 GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 240 Query: 703 SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758 +TT+S +G+ T D +T +K ET T + + Sbjct: 241 GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295 Query: 759 TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810 T+ SE+ ET S++S VTT + + +GS VS + Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 352 Query: 811 NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869 S M SE S S ++T + E + S + DS Sbjct: 353 TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412 Query: 870 KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923 C T F+T+++S+ A++S + +S+ + T+T+ G+ Sbjct: 413 TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 472 Query: 924 FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979 K G + +S++G ++ + + G VS+ ++ Sbjct: 473 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532 Query: 980 NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039 N + + VS T G+ + E+ S+ G T +ST T Sbjct: 533 NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 585 Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099 ++ + + T ++++ + + +T+ A T + AS + Sbjct: 586 ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 645 Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156 + T+ + + ST+ E + V + G+ E S +T S + T Sbjct: 646 VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 703 Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208 K S SE +T G++T+T + +G+ S + S +T A++ G Sbjct: 704 KVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 759 Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265 +ST+SS +A+ + S ++S+ T + ST+ S +F+++S+ S+ Sbjct: 760 SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817 Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317 T TA + + A S TTT+ TTT+S+ GS + T S + + Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877 Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375 G+ T + + + G + ++ST + T S T + S+ Sbjct: 878 TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937 Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435 + S+ S T + + GS TT + + T G+ ++T + + + + Sbjct: 938 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 997 Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460 +++ + GS V S++GT Sbjct: 998 IEGSETTTVSSTGSETTTV-STTGT 1021 Score = 57.8 bits (138), Expect = 8e-08 Identities = 166/870 (19%), Positives = 303/870 (34%), Gaps = 96/870 (11%) Query: 476 SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535 S T S T + +S E TT+S ++ T + T S+TGS S+ ++T Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674 Query: 536 -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586 E V S T S+ ++T ++S GS +T S+ +TT + T Sbjct: 675 TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---TTSTEGSEITTASITG-S 730 Query: 587 KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646 +T EG EGS + G ++ A T++ + + + Sbjct: 731 ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 784 Query: 647 SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706 +S IG + + +S + T +N ++ + A++ + TA I +T Sbjct: 785 ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 842 Query: 707 TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766 T + S G G+ ++ + ET T + + T T +E Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 900 Query: 767 AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 +ET TAS+ +TT + + S + S + ++V Sbjct: 901 SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 947 Query: 827 ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886 + S T+ VS EGS + + ++ + E+ T Sbjct: 948 TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993 Query: 887 GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946 + S + SS+ + S++G T+TST G + S++ ++ Sbjct: 994 TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAVYTT 1049 Query: 947 SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006 + G VS+ + + S + S + + Sbjct: 1050 GSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYIT 1109 Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTI-ETKSASVAPFTC 1065 + + S A +++T + T T+ ++ + T+ ET + S Sbjct: 1110 GSKTTTASTEGSEA------TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163 Query: 1066 KTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNE 1125 TS A E T + E + +AS T T+T+ G + Sbjct: 1164 TTSSAAGSEATTT-------STEGSETTTASTAGSETTTASTAGSETTTASTAGSETT-- 1214 Query: 1126 EPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGA 1185 + + E ++ T + PS SE F G++T T A + Sbjct: 1215 -----------TASTSGSETNTACTTGSETSTPSSAGSE--TNTAFIIGSET-TIASTAS 1260 Query: 1186 AKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF----- 1240 +P + L + S ++T + +A G S+T SS V T S P++++ Sbjct: 1261 LEPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRT 1318 Query: 1241 -GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTS 1297 G +S+S ++ D + S T + G G S+ ++TTS G TT S Sbjct: 1319 TGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGS 1378 Query: 1298 SSAGSSFVF-GTGPSAPSASPAFGANQTPT 1326 + +S F TGP + + + TPT Sbjct: 1379 TREPTSSTFQETGPVSMGTN-TVSMSHTPT 1407 Score = 41.6 bits (96), Expect = 0.006 Identities = 50/197 (25%), Positives = 80/197 (40%), Gaps = 29/197 (14%) Query: 1277 PGASSNNTTTSGFGF---------GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327 P A SN TT S G TTT+S+AGS T PS + + Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET---TTPSPTGSQTTIVSISGSEI 65 Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ-SAFGSG 1386 + A N + S +T GS+ T G S ++ + G + + SA GS Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG--SETTTVSITGTETTMVSAMGSE 123 Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446 TT NS+++ S TT + + + V T G+ ++T + +++ AA T Sbjct: 124 TTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYTAD----------SETTAAST 169 Query: 1447 VGSNGKNVFSSSGTSFS 1463 GS VF++ + + Sbjct: 170 TGSEMTTVFTAGSETIT 186 >gi|239513940 PREDICTED: hypothetical protein [Homo sapiens] Length = 1521 Score = 99.4 bits (246), Expect = 2e-20 Identities = 207/1055 (19%), Positives = 376/1055 (35%), Gaps = 112/1055 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 TSS + + E TT S ++ A T + T+ S+TGS M + + + + Sbjct: 130 TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM----TTVFTAGSETI 185 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599 P ++ T +V A + + S++ E +S+AH TT ST +T G Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245 Query: 600 AE------------------ILKEGSVLDILKSPGFASPKIDSVAAQPTATS-------- 633 E S + GF + + ++PT S Sbjct: 246 VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTM 305 Query: 634 -----PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-- 686 P SS ++ G S+ +T + ++ + ++ Sbjct: 306 ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365 Query: 687 -----SPRDTAKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEA 739 S TA G ET S G + S TG + + TC ++ A Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425 Query: 740 IKCVACETPKPGT------------------CVKRALTLTVVSESAETMTA-SSSSCTVT 780 + ET T + + T TV + +ET TA ++ S T T Sbjct: 426 VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485 Query: 781 TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS--- 836 G IGS S + VS SE S S ++TV + Sbjct: 486 ASNTGLETTTVFTIGS---DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSE 542 Query: 837 LPSGGSLGLE-KFKKPEGS-------WDCELCLVQNKADSTKCLACESAKPGTKSGFKGF 888 + + GLE EGS E + T + ++ T S Sbjct: 543 TTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSE 602 Query: 889 DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE 948 +T++S+++S +S+ G ++++ + + T+T + + G + S++ ++ Sbjct: 603 NTTASTADSETTSASTTGSETTTASTTSSETTTASTE-GSETTTVSTTDSETTMVSTTGS 661 Query: 949 GFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQE 1008 + G VS+ V + ++ + VS T G Sbjct: 662 ERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTT----GSETTTTS 716 Query: 1009 EKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTS 1068 + E+ +S G T + + SE S+ G+ T +++ + T S Sbjct: 717 TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776 Query: 1069 EAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPK 1128 E A+ G V AS +VF E + + ST+ + Sbjct: 777 IMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAGSE 831 Query: 1129 CQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTADQG 1184 P + G+ + T E S +T S S T + ES + AT G++T+T + +G Sbjct: 832 TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTASTEG 890 Query: 1185 AAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTA 1244 + S + S +T A++ G I ST+ S A+ +++ + + T Sbjct: 891 SETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTV 946 Query: 1245 ESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-- 1302 ++ S+++ S + TT +T + T G+ + +T+G TTT+S GS Sbjct: 947 STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGSET 1003 Query: 1303 SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF 1362 + V TG + S G T T + + G S +TA++ TGS+ T Sbjct: 1004 TTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE----TT 1054 Query: 1363 GTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS 1422 T + S+ S++ S +++ GS TT + + + V+ G+ ++ Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114 Query: 1423 TPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457 T + + + +++ A T GS VF++ Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149 Score = 86.3 bits (212), Expect = 2e-16 Identities = 191/1007 (18%), Positives = 371/1007 (36%), Gaps = 107/1007 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T S T + E +T S + ++ A T + T+ S+ GS S+ ++T ++ Sbjct: 349 TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598 + + + +E++ S+T+ E +S+ T+ ST+ +T EG Sbjct: 409 TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 462 Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658 + GS + G + + + T V+T I S +++ G A Sbjct: 463 TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 515 Query: 659 GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716 S+ + + + ++N ++ ++ + T TG+ET S G + S TG Sbjct: 516 VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 572 Query: 717 DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776 G+ ++ + E T T + + +ET TAS++S Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 630 Query: 777 CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836 TT + GS +V + ++E + SE+ +S S ++TV + Sbjct: 631 SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 679 Query: 837 LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896 G E EGS + + ++ E+ T+ + + S Sbjct: 680 -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732 Query: 897 SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956 + AS+ ++S+ G T ST G + SS++ + M + I Sbjct: 733 TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 788 Query: 957 GDFKFGVSS-ESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELP 1015 G VS+ SK V ++ +S + + S G E Sbjct: 789 GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT--- 845 Query: 1016 KSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEM 1075 +S+ G T + + +SE ++ +G+ T +++ T TS E Sbjct: 846 -TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904 Query: 1076 PATKGGFSFGNVEPASLPSASVFVLGR------TEEKQQEPVTST-SLVFGKKADNEEPK 1128 A+ G V + + G TE + V++T S A+ E Sbjct: 905 TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964 Query: 1129 CQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATF--AFGAQTSTTADQGAA 1186 V + G+ T S++T + + S + ++ T + G++T+T + G Sbjct: 965 T--VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1022 Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246 + S + S +T T+AG T+ S + +++ ++ + TA + Sbjct: 1023 TTITS----TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078 Query: 1247 STSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVF 1306 + ++ S TT+ST + T V+ G S TT S G ATT S+++ Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSETTTVYITG--SKTTTASTEGSEATTVSTTS------ 1130 Query: 1307 GTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVS 1366 S + + G+ T F ++S +T + GS+ + Sbjct: 1131 ----SETTTASTTGSEMTTV--------------FTTVSETTTVSTIGSEATTSSAAGSE 1172 Query: 1367 SSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAA 1426 +++ + + S GS TT S++ GS TT + + + + T G+ +STP++ Sbjct: 1173 ATTTSTEGSETTTASTAGSETTTASTA----GSETTTASTSGSETNTACTTGSETSTPSS 1228 Query: 1427 SAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSS----GTSFSGRKIKT 1469 + +++ AF +GS ++S TS +G + T Sbjct: 1229 AG----------SETNTAFIIGSESTIASTASLEPTATSLTGSETTT 1265 Score = 85.1 bits (209), Expect = 5e-16 Identities = 157/800 (19%), Positives = 285/800 (35%), Gaps = 65/800 (8%) Query: 691 TAKQTGIETP-NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749 TA G ET + +G T + S TG +G+ ++ ET Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146 Query: 750 PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809 T T T + +ET AS++ +TT + E + VS Sbjct: 147 VSTVGSE--TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTT--VSTAGS 202 Query: 810 DNKCVSCMSEKPGSSVPASSSSTVPVSLPSG----GSLGLEKFKKPEGSWDCELCLVQNK 865 + VS + ++ A S +T ++ S + G E GS E + Sbjct: 203 ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---ETTAASTE 259 Query: 866 ADSTKCLACESAKPGTKSGFKGFDTSSSSSNSA----ASSSFKFGVSSSSSGPSQTLTST 921 T E +K T S GF+T+++S+ + AS+ +S+ GP T ST Sbjct: 260 DSETNTAFTEDSKTTTAST-TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVST 318 Query: 922 GN------FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975 + F G + V S++ +++ + +G S+ Sbjct: 319 ASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTAST 378 Query: 976 SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035 ++ + VS T + ++ E + S T +T + Sbjct: 379 EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438 Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095 + +T + S T T+ + T SE K A G L + Sbjct: 439 EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT----AYTTGSETTTASNTGLETT 494 Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK-----DENSSKST 1150 +VF +G + T+ V ++ S SE T E ++ ST Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSE------MTTVSTEGSENTTVSTTGSETTTVST 548 Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210 T S + SE +T GA+T+T + +G S +T A++AG Sbjct: 549 TGLETTTTSTEGSEMTTVSTT--GAETTTDSTEG--------------SGTTAASTAGSE 592 Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV 1270 ST+ S A+ ++++ ++ + TA +++S++ S + TT ST + Sbjct: 593 TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652 Query: 1271 TPFVFGPGA--------SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGAN 1322 T V G+ S TT S G T ++ +G++ V TG S G+ Sbjct: 653 TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-GSE 711 Query: 1323 QTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380 T T + + + G + ++ST + T S T ++ S+ S+ Sbjct: 712 TTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771 Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440 + S ++ A GS TT + ++ + VFT + ++ + +A + + ++ Sbjct: 772 TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831 Query: 1441 SPAAFTVGSNGKNVFSSSGT 1460 + A T GS S+ G+ Sbjct: 832 TIPASTAGSETTTTTSTEGS 851 Score = 79.0 bits (193), Expect = 3e-14 Identities = 193/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%) Query: 478 PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537 P S+ T + + E TT ++ A T + T+PS TGS S + T Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 68 Query: 538 NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582 + + + + TA ++GS +T+ E + S+ TT NS Sbjct: 69 STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS 128 Query: 583 TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642 T +T G E + + + S + DS + T + T Sbjct: 129 TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180 Query: 643 SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702 S + + G S+ +T + ++ + ++ + T + Sbjct: 181 GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 240 Query: 703 SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758 +TT+S +G+ T D +T +K ET T + + Sbjct: 241 GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295 Query: 759 TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810 T+ SE+ ET S++S VTT + + +GS VS + Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 352 Query: 811 NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869 S M SE S S ++T + E + S + DS Sbjct: 353 TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412 Query: 870 KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923 C T F+T+++S+ A++S + +S+ + T+T+ G+ Sbjct: 413 TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 472 Query: 924 FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979 K G + +S++G ++ + + G VS+ ++ Sbjct: 473 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532 Query: 980 NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039 N + + VS T G+ + E+ S+ G T +ST T Sbjct: 533 NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 585 Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099 ++ + + T ++++ + + +T+ A T + AS + Sbjct: 586 ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 645 Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156 + T+ + + ST+ E + V + G+ E S +T S + T Sbjct: 646 VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 703 Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208 K S SE +T G++T+T + +G+ S + S +T A++ G Sbjct: 704 KVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 759 Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265 +ST+SS +A+ + S ++S+ T + ST+ S +F+++S+ S+ Sbjct: 760 SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817 Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317 T TA + + A S TTT+ TTT+S+ GS + T S + + Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877 Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375 G+ T + + + G + ++ST + T S T + S+ Sbjct: 878 TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937 Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435 + S+ S T + + GS TT + + T G+ ++T + + + + Sbjct: 938 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 997 Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460 +++ + GS V S++GT Sbjct: 998 IEGSETTTVSSTGSETTTV-STTGT 1021 Score = 75.5 bits (184), Expect = 4e-13 Identities = 189/936 (20%), Positives = 323/936 (34%), Gaps = 102/936 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTE--- 536 T S + T + E TT S + ++ T ++ T+ S+ GS M S+ ++T Sbjct: 519 TGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST 578 Query: 537 --ANVLPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDC 593 + S+ G T +V A + + S++ E +S+ TT ST +T Sbjct: 579 EGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAST 638 Query: 594 EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSS----G 649 EG + S ++ + G + I S T T + +S+ S Sbjct: 639 EGS-ETTTVSTTDSETTMVSTTG-SERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696 Query: 650 IGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTT 707 I E+ K ++ T T+ I + S TA G ET S G T Sbjct: 697 ITGSETTKVSTTGSETT----TTSTEGSEITTASITGSETTTASTEGSETTTASTEGSET 752 Query: 708 LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767 SAS TG + ++ ++ + ET K T + T V +E++ Sbjct: 753 TSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT--VFTENS 810 Query: 768 ETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPA 827 ET AS+++ TT + + E + + +E + SE +S + Sbjct: 811 ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTES 870 Query: 828 SSSSTVPVSLPSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886 S ++T ++G E EGS E + T + E ++ T S Sbjct: 871 SETTTAT-------TIGSETTTASTEGS---ETTTTSTEGSETTTASTEGSEITTVS--- 917 Query: 887 GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS---SDSGSI 943 ++ S + AS+ ++S+ G T ST G I VS S++ ++ Sbjct: 918 ----TTGSETTTASTEGSETTTASTEGSELTTVST-------TGSETITVSAEGSETTTV 966 Query: 944 NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVS 1003 M + G VS+ ++ + + VS T + ++ Sbjct: 967 TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTIT 1026 Query: 1004 NLGQEEKKEELPKSSSAGFSFGTG---VINSTPAPANTIVTSENKSSFNLGTIETKSASV 1060 + E S + TG ST T V++ + T + ++ +V Sbjct: 1027 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTV 1086 Query: 1061 APFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS---LV 1117 + T+ A T + AS + + T + T+ S V Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146 Query: 1118 FGKKADNEEPKC----QPVFSFGNSEQTK-----DENSSKSTFSFSMTKPSEKESEQPAK 1168 F ++ S SE T E ++ ST T S SE Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTA 1206 Query: 1169 ATFAF--------GAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSN 1220 +T G++TST + G+ + + S+ +ST +S Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIAST---------------ASL 1251 Query: 1221 PPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGAS 1280 P AT + G + VS +A G TA S+T S F T +T ++ P P + Sbjct: 1252 EPTATSLTGSETTTVSITASGATAASTTVSSTTF------VLTKATDVSIQPITNTPMSG 1305 Query: 1281 SNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPG 1340 + T G T +SS + + T +A P N + + GAS Sbjct: 1306 TRTT-----GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAH 1360 Query: 1341 FGSISSSTALFPTGS---QPAPPTFG--TVSSSSQP 1371 ++ + PT S + P + G TVS S P Sbjct: 1361 GVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTP 1396 Score = 54.3 bits (129), Expect = 9e-07 Identities = 165/869 (18%), Positives = 302/869 (34%), Gaps = 104/869 (11%) Query: 476 SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535 S T S T + +S E TT+S ++ T + T S+TGS S+ ++T Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674 Query: 536 -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586 E V S T S+ ++T ++S GS +T S+ +TT + T Sbjct: 675 TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---TTSTEGSEITTASITG-S 730 Query: 587 KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646 +T EG EGS + G ++ A T++ + + + Sbjct: 731 ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 784 Query: 647 SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706 +S IG + + +S + T +N ++ + A++ + TA I +T Sbjct: 785 ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 842 Query: 707 TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766 T + S G G+ ++ + ET T + + T T +E Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 900 Query: 767 AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 +ET TAS+ +TT + + S + S + ++V Sbjct: 901 SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 947 Query: 827 ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886 + S T+ VS EGS + + ++ + E+ T Sbjct: 948 TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993 Query: 887 GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946 + S + SS+ + S++G T+TST G + S++ ++ Sbjct: 994 TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAV--- 1046 Query: 947 SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006 + SE+ + G + ++ L S G Sbjct: 1047 --------------YTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066 ++++ + TG +T + + T+ + +S T T + + Sbjct: 1093 TTTASTAGSETTTV---YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149 Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126 SE T + G+ S + S TE + T+T+ G + Sbjct: 1150 VSE--------TTTVSTIGSEATTSSAAGSEATTTSTEGSE----TTTASTAGSETTTAS 1197 Query: 1127 PKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAA 1186 + S E ++ T + PS SE F G++ ST A + Sbjct: 1198 TAGSETTTASTS---GSETNTACTTGSETSTPSSAGSE--TNTAFIIGSE-STIASTASL 1251 Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF------ 1240 +P + L + S ++T + +A G S+T SS V T S P++++ Sbjct: 1252 EPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1309 Query: 1241 GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTSS 1298 G +S+S ++ D + S T + G G S+ ++TTS G TT S+ Sbjct: 1310 GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369 Query: 1299 SAGSSFVF-GTGPSAPSASPAFGANQTPT 1326 +S F TGP + + + TPT Sbjct: 1370 REPTSSTFQETGPVSMGTN-TVSMSHTPT 1397 Score = 41.6 bits (96), Expect = 0.006 Identities = 50/197 (25%), Positives = 80/197 (40%), Gaps = 29/197 (14%) Query: 1277 PGASSNNTTTSGFGF---------GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327 P A SN TT S G TTT+S+AGS T PS + + Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET---TTPSPTGSQTTIVSISGSEI 65 Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ-SAFGSG 1386 + A N + S +T GS+ T G S ++ + G + + SA GS Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG--SETTTVSITGTETTMVSAMGSE 123 Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446 TT NS+++ S TT + + + V T G+ ++T + +++ AA T Sbjct: 124 TTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYTAD----------SETTAAST 169 Query: 1447 VGSNGKNVFSSSGTSFS 1463 GS VF++ + + Sbjct: 170 TGSEMTTVFTAGSETIT 186 >gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo sapiens] Length = 1521 Score = 99.0 bits (245), Expect = 3e-20 Identities = 206/1055 (19%), Positives = 379/1055 (35%), Gaps = 112/1055 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 TSS + + E TT S ++ A T + T+ S+TGS M + + + + Sbjct: 130 TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM----TTVFTAGSETI 185 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599 P ++ T +V A + + S++ E +S+AH TT ST +T G Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245 Query: 600 AE------------------ILKEGSVLDILKSPGFASPKIDSVAAQPTATS-------- 633 E S + GF + + ++PT S Sbjct: 246 VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTM 305 Query: 634 -----PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-- 686 P SS ++ G S+ +T + ++ + ++ Sbjct: 306 ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365 Query: 687 -----SPRDTAKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEA 739 S TA G ET S G + S TG + + TC ++ A Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425 Query: 740 IKCVACETPKPGT------------------CVKRALTLTVVSESAETMTA-SSSSCTVT 780 + ET T + + T TV + +ET TA ++ S T T Sbjct: 426 VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485 Query: 781 TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS--- 836 G IGS S + VS SE S S ++TV + Sbjct: 486 ASNTGLETTTVFTIGS---DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSE 542 Query: 837 LPSGGSLGLE-KFKKPEGS-------WDCELCLVQNKADSTKCLACESAKPGTKSGFKGF 888 + + GLE EGS E + T + ++ T S Sbjct: 543 TTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSE 602 Query: 889 DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE 948 +T++S+++S +S+ G ++++ + + T+T + + G + S++ ++ Sbjct: 603 NTTASTADSETTSASTTGSETTTASTTSSETTTASTE-GSETTTVSTTDSETTMVSTTGS 661 Query: 949 GFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQE 1008 + G VS+ V + ++ + VS T + +++ Sbjct: 662 ERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTTGSETTITS---- 716 Query: 1009 EKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTS 1068 + E+ +S G T + + SE S+ G+ T +++ + T S Sbjct: 717 TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776 Query: 1069 EAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPK 1128 E A+ G V AS +VF E + + ST+ + Sbjct: 777 IMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAGSE 831 Query: 1129 CQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTADQG 1184 P + G+ + T E S +T S S T + ES + AT G++T+T + +G Sbjct: 832 TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTASTEG 890 Query: 1185 AAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTA 1244 + S + S +T A++ G I ST+ S A+ +++ + + T Sbjct: 891 SETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTV 946 Query: 1245 ESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-- 1302 ++ S+++ S + TT +T + T G+ + +T+G TTT+S GS Sbjct: 947 STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGSET 1003 Query: 1303 SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF 1362 + V TG + S G T T + + G S +TA++ TGS+ T Sbjct: 1004 TTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE----TT 1054 Query: 1363 GTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS 1422 T + S+ S++ S +++ GS TT + + + V+ G+ ++ Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114 Query: 1423 TPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457 T + + + +++ A T GS VF++ Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149 Score = 96.3 bits (238), Expect = 2e-19 Identities = 206/1019 (20%), Positives = 386/1019 (37%), Gaps = 104/1019 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T++S F ++ T S P+ ++ + T P +T V + + Sbjct: 274 TTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET 333 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599 + S++G + T +GS +T I+ S T+ +ST +T EG Sbjct: 334 IRASTVGSETT-----TVSTTGSETTTASIMGSE----TSTDSTTGSETTTASTEGS-ET 383 Query: 600 AEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF-----SSSGIGFGE 654 EGS + + G + + ++ T T A+S+ ++S G Sbjct: 384 TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443 Query: 655 SLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-----SPRDTAKQTGIETPN--KSGKTT 707 ++ + S + T + T A K S TA TG+ET G T Sbjct: 444 TIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDT 503 Query: 708 LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767 +AS G G+ ++ + ET T T T +E + Sbjct: 504 TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLE--TTTTSTEGS 561 Query: 768 ETMTASSSSCTVTT-GTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 E T S++ TT T G G GS +V ++E+ + SE +S Sbjct: 562 EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA--DSENTTASTADSETTSASTT 619 Query: 827 ASSSSTVPVSLPSGGSLGLEKFKKPEGSW-DCELCLVQNKADSTKCLACESAKPGTKSGF 885 S ++T + + E + S D E +V + E ++ T S Sbjct: 620 GSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSA- 678 Query: 886 KGFDTSSSSSNSAASSSFKFGVSS---SSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGS 942 G +T+ S+ S ++ G + S++G T+TST G +I +S +GS Sbjct: 679 TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTE--------GSEITTASITGS 730 Query: 943 --INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQF 1000 +EG + + + S+ + E S + + ++S + + ++ Sbjct: 731 ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSS-ETTMASIMGSETTMA---- 785 Query: 1001 GVSNLGQEEKKEELPKSSSAGF---SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS 1057 S +G E K S + T + ++T + T+ T+ ++ TI + Sbjct: 786 --STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE------TIPAST 837 Query: 1058 ASVAPFTCKTSEAKKEEMPATKGG-FSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSL 1116 A T ++E + +T+G + + E + +A+ T + T+T+ Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897 Query: 1117 VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQ 1176 G + + + + T E ++ ST T S + SE +T G++ Sbjct: 898 TEGSETTTASTEGSEITTVST---TGSETTTASTEGSETTTASTEGSELTTVSTT--GSE 952 Query: 1177 TSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVS 1236 T T + +G+ + + S +T A++AG ST+ S A+ + G + VS Sbjct: 953 TITVSAEGSETTTVTTMG----SETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVS 1007 Query: 1237 SSAFGNTAESST-SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATT 1295 S+ T S+T +++ + S + TT +T + T V+ G+ + T+T G TT Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG---SETT 1064 Query: 1296 TSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGS 1355 T S+ GS + A A+ T + G+ GS +T ++ TGS Sbjct: 1065 TVSTTGSE-----------TTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGS 1111 Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415 + T ++S++ S++ S T+ +++A GS T T + + V Sbjct: 1112 K-------TTTASTEG-------SEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVS 1157 Query: 1416 TFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSG----TSFSGRKIKTA 1470 T G+ ++T +A+ + + +++ A T GS ++ S SG + TA Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTA 1216 Score = 85.9 bits (211), Expect = 3e-16 Identities = 186/973 (19%), Positives = 359/973 (36%), Gaps = 75/973 (7%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539 T S T + E +T S + ++ A T + T+ S+ GS S+ ++T ++ Sbjct: 349 TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408 Query: 540 LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598 + + + +E++ S+T+ E +S+ T+ ST+ +T EG Sbjct: 409 TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 462 Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658 + GS + G + + + T V+T I S +++ G A Sbjct: 463 TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 515 Query: 659 GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716 S+ + + + ++N ++ ++ + T TG+ET S G + S TG Sbjct: 516 VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 572 Query: 717 DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776 G+ ++ + E T T + + +ET TAS++S Sbjct: 573 TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 630 Query: 777 CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836 TT + GS +V + ++E + SE+ +S S ++TV + Sbjct: 631 SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 679 Query: 837 LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896 G E EGS + + ++ E+ T+ + + S Sbjct: 680 -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSET 732 Query: 897 SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956 + AS+ ++S+ G T ST G + SS++ + M + I Sbjct: 733 TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 788 Query: 957 GDFKFGVSS-ESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELP 1015 G VS+ SK V ++ +S + + S G E Sbjct: 789 GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT--- 845 Query: 1016 KSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEM 1075 +S+ G T + + +SE ++ +G+ T +++ T TS E Sbjct: 846 -TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904 Query: 1076 PATKGGFSFGNVEPASLPSASVFVLGR------TEEKQQEPVTST-SLVFGKKADNEEPK 1128 A+ G V + + G TE + V++T S A+ E Sbjct: 905 TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964 Query: 1129 CQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATF--AFGAQTSTTADQGAA 1186 V + G+ T S++T + + S + ++ T + G++T+T + G Sbjct: 965 T--VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1022 Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246 + S + S +T T+AG T+ S + +++ ++ + TA + Sbjct: 1023 TTITS----TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078 Query: 1247 STSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSG-------FGFGATTTSSS 1299 + ++ S TT+ST + T V+ G+ + +T G TTT+S+ Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAST 1138 Query: 1300 AGSSF--VFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTA--LFPTGS 1355 GS VF T + S G+ T + A+ + G + ++STA T S Sbjct: 1139 TGSEMTTVFTTVSETTTVS-TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1197 Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415 T +S S+ S+++ S +++AF GS TT + + P+ Sbjct: 1198 TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATS 1257 Query: 1416 TFGANSSTPAASA 1428 G+ ++T + +A Sbjct: 1258 LTGSETTTVSITA 1270 Score = 84.3 bits (207), Expect = 8e-16 Identities = 157/800 (19%), Positives = 285/800 (35%), Gaps = 65/800 (8%) Query: 691 TAKQTGIETP-NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749 TA G ET + +G T + S TG +G+ ++ ET Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146 Query: 750 PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809 T T T + +ET AS++ +TT + E + VS Sbjct: 147 VSTVGSE--TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTT--VSTAGS 202 Query: 810 DNKCVSCMSEKPGSSVPASSSSTVPVSLPSG----GSLGLEKFKKPEGSWDCELCLVQNK 865 + VS + ++ A S +T ++ S + G E GS E + Sbjct: 203 ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---ETTAASTE 259 Query: 866 ADSTKCLACESAKPGTKSGFKGFDTSSSSSNSA----ASSSFKFGVSSSSSGPSQTLTST 921 T E +K T S GF+T+++S+ + AS+ +S+ GP T ST Sbjct: 260 DSETNTAFTEDSKTTTAST-TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVST 318 Query: 922 GN------FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975 + F G + V S++ +++ + +G S+ Sbjct: 319 ASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTAST 378 Query: 976 SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035 ++ + VS T + ++ E + S T +T + Sbjct: 379 EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438 Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095 + +T + S T T+ + T SE K A G L + Sbjct: 439 EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT----AYTTGSETTTASNTGLETT 494 Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK-----DENSSKST 1150 +VF +G + T+ V ++ S SE T E ++ ST Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSE------MTTVSTEGSENTTVSTTGSETTTVST 548 Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210 T S + SE +T GA+T+T + +G S +T A++AG Sbjct: 549 TGLETTTTSTEGSEMTTVSTT--GAETTTDSTEG--------------SGTTAASTAGSE 592 Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV 1270 ST+ S A+ ++++ ++ + TA +++S++ S + TT ST + Sbjct: 593 TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652 Query: 1271 TPFVFGPGA--------SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGAN 1322 T V G+ S TT S G T ++ +G++ V TG S G+ Sbjct: 653 TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-GSE 711 Query: 1323 QTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380 T T + + + G + ++ST + T S T ++ S+ S+ Sbjct: 712 TTITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771 Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440 + S ++ A GS TT + ++ + VFT + ++ + +A + + ++ Sbjct: 772 TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831 Query: 1441 SPAAFTVGSNGKNVFSSSGT 1460 + A T GS S+ G+ Sbjct: 832 TIPASTAGSETTTTTSTEGS 851 Score = 78.6 bits (192), Expect = 4e-14 Identities = 193/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%) Query: 478 PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537 P S+ T + + E TT ++ A T + T+PS TGS S + T Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 68 Query: 538 NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582 + + + + TA ++GS +T+ E + S+ TT NS Sbjct: 69 STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS 128 Query: 583 TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642 T +T G E + + + S + DS + T + T Sbjct: 129 TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180 Query: 643 SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702 S + + G S+ +T + ++ + ++ + T + Sbjct: 181 GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 240 Query: 703 SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758 +TT+S +G+ T D +T +K ET T + + Sbjct: 241 GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295 Query: 759 TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810 T+ SE+ ET S++S VTT + + +GS VS + Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 352 Query: 811 NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869 S M SE S S ++T + E + S + DS Sbjct: 353 TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412 Query: 870 KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923 C T F+T+++S+ A++S + +S+ + T+T+ G+ Sbjct: 413 TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 472 Query: 924 FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979 K G + +S++G ++ + + G VS+ ++ Sbjct: 473 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532 Query: 980 NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039 N + + VS T G+ + E+ S+ G T +ST T Sbjct: 533 NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 585 Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099 ++ + + T ++++ + + +T+ A T + AS + Sbjct: 586 ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 645 Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156 + T+ + + ST+ E + V + G+ E S +T S + T Sbjct: 646 VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 703 Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208 K S SE +T G++T+T + +G+ S + S +T A++ G Sbjct: 704 KVSTTGSETTITSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 759 Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265 +ST+SS +A+ + S ++S+ T + ST+ S +F+++S+ S+ Sbjct: 760 SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817 Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317 T TA + + A S TTT+ TTT+S+ GS + T S + + Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877 Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375 G+ T + + + G + ++ST + T S T + S+ Sbjct: 878 TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937 Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435 + S+ S T + + GS TT + + T G+ ++T + + + + Sbjct: 938 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 997 Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460 +++ + GS V S++GT Sbjct: 998 IEGSETTTVSSTGSETTTV-STTGT 1021 Score = 75.1 bits (183), Expect = 5e-13 Identities = 186/934 (19%), Positives = 323/934 (34%), Gaps = 98/934 (10%) Query: 480 TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTE--- 536 T S + T + E TT S + ++ T ++ T+ S+ GS M S+ ++T Sbjct: 519 TGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST 578 Query: 537 --ANVLPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDC 593 + S+ G T +V A + + S++ E +S+ TT ST +T Sbjct: 579 EGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAST 638 Query: 594 EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFG 653 EG + S ++ + G + I S T T + +S+ S Sbjct: 639 EGS-ETTTVSTTDSETTMVSTTG-SERTITSTEGSETTTVSATGSETTVSTEGSGTTTV- 695 Query: 654 ESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL--SPRDTAKQTGIETPNKS--GKTTLS 709 S+ + + T + +T + A + S TA G ET S G T S Sbjct: 696 -SITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTS 754 Query: 710 ASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAET 769 AS TG + ++ ++ + ET K T + T V +E++ET Sbjct: 755 ASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT--VFTENSET 812 Query: 770 MTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASS 829 AS+++ TT + + E + + +E + SE +S +S Sbjct: 813 TIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSE 872 Query: 830 SSTVPVSLPSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGF 888 ++T ++G E EGS E + T + E ++ T S Sbjct: 873 TTTAT-------TIGSETTTASTEGS---ETTTTSTEGSETTTASTEGSEITTVS----- 917 Query: 889 DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS---SDSGSINP 945 ++ S + AS+ ++S+ G T ST G I VS S++ ++ Sbjct: 918 --TTGSETTTASTEGSETTTASTEGSELTTVST-------TGSETITVSAEGSETTTVTT 968 Query: 946 MSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNL 1005 M + G VS+ ++ + + VS T + +++ Sbjct: 969 MGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITST 1028 Query: 1006 GQEEKKEELPKSSSAGFSFGTG---VINSTPAPANTIVTSENKSSFNLGTIETKSASVAP 1062 E S + TG ST T V++ + T + ++ +V+ Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVST 1088 Query: 1063 FTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS---LVFG 1119 T+ A T + AS + + T + T+ S VF Sbjct: 1089 SGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFT 1148 Query: 1120 KKADNEEPKC----QPVFSFGNSEQTK-----DENSSKSTFSFSMTKPSEKESEQPAKAT 1170 ++ S SE T E ++ ST T S SE +T Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208 Query: 1171 FAF--------GAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPP 1222 G++TST + G+ + + ++ +ST +S P Sbjct: 1209 SGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAST---------------ASLEP 1253 Query: 1223 VATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSN 1282 AT + G + VS +A G TA S+T S F T +T ++ P P + + Sbjct: 1254 TATSLTGSETTTVSITASGATAASTTVSSTTF------VLTKATDVSIQPITNTPMSGTR 1307 Query: 1283 NTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFG 1342 T G T +SS + + T +A P N + + GAS Sbjct: 1308 TT-----GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGV 1362 Query: 1343 SISSSTALFPTGS---QPAPPTFG--TVSSSSQP 1371 ++ + PT S + P + G TVS S P Sbjct: 1363 RTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTP 1396 Score = 56.6 bits (135), Expect = 2e-07 Identities = 166/869 (19%), Positives = 303/869 (34%), Gaps = 104/869 (11%) Query: 476 SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535 S T S T + +S E TT+S ++ T + T S+TGS S+ ++T Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674 Query: 536 -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586 E V S T S+ ++T ++S GS +T I S+ +TT + T Sbjct: 675 TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---ITSTEGSEITTASITG-S 730 Query: 587 KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646 +T EG EGS + G ++ A T++ + + + Sbjct: 731 ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 784 Query: 647 SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706 +S IG + + +S + T +N ++ + A++ + TA I +T Sbjct: 785 ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 842 Query: 707 TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766 T + S G G+ ++ + ET T + + T T +E Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 900 Query: 767 AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 +ET TAS+ +TT + + S + S + ++V Sbjct: 901 SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 947 Query: 827 ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886 + S T+ VS EGS + + ++ + E+ T Sbjct: 948 TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993 Query: 887 GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946 + S + SS+ + S++G T+TST G + S++ ++ Sbjct: 994 TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAV--- 1046 Query: 947 SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006 + SE+ + G + ++ L S G Sbjct: 1047 --------------YTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066 ++++ + TG +T + + T+ + +S T T + + Sbjct: 1093 TTTASTAGSETTTV---YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149 Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126 SE T + G+ S + S TE + T+T+ G + Sbjct: 1150 VSE--------TTTVSTIGSEATTSSAAGSEATTTSTEGSE----TTTASTAGSETTTAS 1197 Query: 1127 PKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAA 1186 + S E ++ T + PS SE F G++T T A + Sbjct: 1198 TAGSETTTASTS---GSETNTACTTGSETSTPSSAGSE--TNTAFIIGSET-TIASTASL 1251 Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF------ 1240 +P + L + S ++T + +A G S+T SS V T S P++++ Sbjct: 1252 EPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1309 Query: 1241 GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTSS 1298 G +S+S ++ D + S T + G G S+ ++TTS G TT S+ Sbjct: 1310 GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369 Query: 1299 SAGSSFVF-GTGPSAPSASPAFGANQTPT 1326 +S F TGP + + + TPT Sbjct: 1370 REPTSSTFQETGPVSMGTN-TVSMSHTPT 1397 Score = 41.6 bits (96), Expect = 0.006 Identities = 50/197 (25%), Positives = 80/197 (40%), Gaps = 29/197 (14%) Query: 1277 PGASSNNTTTSGFGF---------GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327 P A SN TT S G TTT+S+AGS T PS + + Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET---TTPSPTGSQTTIVSISGSEI 65 Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ-SAFGSG 1386 + A N + S +T GS+ T G S ++ + G + + SA GS Sbjct: 66 TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG--SETTTVSITGTETTMVSAMGSE 123 Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446 TT NS+++ S TT + + + V T G+ ++T + +++ AA T Sbjct: 124 TTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYTAD----------SETTAAST 169 Query: 1447 VGSNGKNVFSSSGTSFS 1463 GS VF++ + + Sbjct: 170 TGSEMTTVFTAGSETIT 186 >gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo sapiens] Length = 834 Score = 91.7 bits (226), Expect = 5e-18 Identities = 145/585 (24%), Positives = 213/585 (36%), Gaps = 128/585 (21%) Query: 823 SSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKP--- 879 SS+P ++S+T P P S+G P S L K +T A + P Sbjct: 342 SSLPTTTSTTAPTFQPVFSSMG------PPAS--VPLPAPFFKQTTTPATAPTTTAPLFT 393 Query: 880 ---GTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGN-----FKFGDQGG 931 S ++S S++SA+ +F FG++S SS T TST F FG Sbjct: 394 GLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG---- 449 Query: 932 FKIGVSSDSGSINPMSEGFKFSKPIGD-FKFGVSSESKPEEVKKDSKNDNFKFGLSSGLS 990 P + F+ +G F+FG KP + + F L + + Sbjct: 450 ------------APQASAASFTPAMGSIFQFG-----KPPALPTTTTVTTFSQSLPTAVP 492 Query: 991 NPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFS-FGTGVINSTPAPANTIVTSENKSSFN 1049 S SS+A FS FG+ + S PA ++ + + +S Sbjct: 493 TATS----------------------SSAADFSGFGSTLATSAPATSSQPTLTFSNTSTP 530 Query: 1050 LGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPS-ASVFVLGRTEEKQQ 1108 I S++ +P + A +G G +PA PS S F G + Sbjct: 531 TFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQ-PPGAAKPALTPSFGSSFTFGNSAAPAA 589 Query: 1109 EPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAK 1168 P + + + QP F ++ S F T Sbjct: 590 APTPAPPSMIKIVPAHVPTPIQPTFG----------GATHSAFGLKAT------------ 627 Query: 1169 ATFAFGAQTSTTADQGAAKPVFSFLNNSSS----SSSTPATSAGGGIFGSSTSSSNPPVA 1224 AFGA S+ G + VFSF +SS ++ T ++ + +FGS+T S Sbjct: 628 -ASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPS------ 680 Query: 1225 TFVFGQSSNPVSSSAFG-NTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNN 1283 F FG S+ P S +FG N A +S ATT + F FG G S + Sbjct: 681 PFTFGGSAAPAGSGSFGINVATPGSS-----------ATTGA-------FSFGAGQSGST 722 Query: 1284 TTTSGF--GFGATTTSSSAGSS-FVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPG 1340 T++ F G G ++ S+ F F G S + P FG TPTFG + A PG Sbjct: 723 ATSTPFAGGLGQNALGTTGQSTPFAFNVG-STTESKPVFGGTATPTFGLNTPA-----PG 776 Query: 1341 FGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGS 1385 G+ S S+ F S PA G S P F G+ Sbjct: 777 VGT-SGSSLSFGASSAPAQGFVGVAPFGSAAPSFSIGAGSKTLGA 820 Score = 85.5 bits (210), Expect = 3e-16 Identities = 141/513 (27%), Positives = 197/513 (38%), Gaps = 139/513 (27%) Query: 1031 STPAPANTIVTSENKSSFNLGTIETKSAS-VAPFTCKTSEAKKEEMPATKGGFSFGNVEP 1089 S P+PA K SF GT T +S AP S K A G P Sbjct: 278 SAPSPAP-------KQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPP 330 Query: 1090 ASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKS 1149 PS S T T+TS P QPVFS S Sbjct: 331 G--PSVSA-----TAPSSSSLPTTTSTT--------APTFQPVFS-----------SMGP 364 Query: 1150 TFSFSMTKPSEKESEQPA--------------KATFAFGAQTSTT-ADQGAAKPVFSFLN 1194 S + P K++ PA AT A TS + + A+KP F F Sbjct: 365 PASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGI 424 Query: 1195 NSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLF 1254 NS SSSS T++ ++T++S P F+FG P +S+A A S Q F Sbjct: 425 NSVSSSSVSTTTS------TATAASQP----FLFGA---PQASAASFTPAMGSIFQ---F 468 Query: 1255 SQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSS----------- 1303 + L TT++ T +++++ GFG+T +S+ +S Sbjct: 469 GKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTS 528 Query: 1304 ---FVFGTGPSAPSASPAF-GANQTPTFG----QSQGASQPN-PPGFGSI-----SSSTA 1349 F G SA S P++ GAN P FG Q GA++P P FGS S++ A Sbjct: 529 TPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPA 588 Query: 1350 LFPTGSQPA-------------PPTFGTVSSS---------------SQPPVFGQQPSQS 1381 PT + P+ PTFG + S S P FG + Sbjct: 589 AAPTPAPPSMIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVF 648 Query: 1382 AFGSGTTPNSSSAFQF---GSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPF 1438 +FG+ T+ + Q GSS++ F T SP FTFG SA P+GSG F Sbjct: 649 SFGAATSSGFGATTQTASSGSSSSVFGSTTPSP---FTFG-------GSAAPAGSGSFGI 698 Query: 1439 N-------QSPAAFTVGSNGKNVFSSSGTSFSG 1464 N + AF+ G+ G++ +++ T F+G Sbjct: 699 NVATPGSSATTGAFSFGA-GQSGSTATSTPFAG 730 Score = 83.2 bits (204), Expect = 2e-15 Identities = 142/535 (26%), Positives = 196/535 (36%), Gaps = 107/535 (20%) Query: 991 NPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFS-FGTGVINST---PAPANTIVTSENKS 1046 +P F FG N S+S F T S P P V++ S Sbjct: 281 SPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVSATAPS 340 Query: 1047 SFNLGTIETKSA-SVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPS--ASVFVLGRT 1103 S +L T + +A + P +PA F PA+ P+ A +F + Sbjct: 341 SSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAP---FFKQTTTPATAPTTTAPLFTGLAS 397 Query: 1104 EEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKES 1163 P+TS S + + +P F FG + S S+ S S T + + Sbjct: 398 ATSAVAPITSAS-------PSTDSASKPAFGFGIN--------SVSSSSVSTTTSTATAA 442 Query: 1164 EQPAKATFAFGA-QTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPP 1222 QP F FGA Q S + A +F F + ++T T+ S + + P Sbjct: 443 SQP----FLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTF------SQSLPTAVP 492 Query: 1223 VATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSN 1282 AT SS+ S FG+T +TS SQ + + +ST T PF G+S+ Sbjct: 493 TAT-----SSSAADFSGFGSTL--ATSAPATSSQPTLTFSNTSTPTFNIPF----GSSAK 541 Query: 1283 NTTTSGFG------FGAT----------TTSSSAGSSFVFGTG--------PSAPSA--- 1315 + S G FGA + S GSSF FG P+ PS Sbjct: 542 SPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAAAPTPAPPSMIKI 601 Query: 1316 ---------SPAFGANQTPTFG-----QSQGASQPNPPGFGSISSSTALFPTGSQPAP-- 1359 P FG FG + GA + P FG STA+F G+ + Sbjct: 602 VPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGG---STAVFSFGAATSSGF 658 Query: 1360 -PTFGTVSSSSQPPVFGQQ-PSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTF 1417 T T SS S VFG PS FG P S +F +T + T +G F+F Sbjct: 659 GATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSAT----TGAFSF 714 Query: 1418 GANSSTPAASAQPSGSG------GFPFNQSPAAFTVGS--NGKNVFSSSGTSFSG 1464 GA S A++ P G G +P AF VGS K VF + T G Sbjct: 715 GAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFG 769 Score = 70.9 bits (172), Expect = 9e-12 Identities = 113/474 (23%), Positives = 178/474 (37%), Gaps = 78/474 (16%) Query: 1033 PAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASL 1092 PAP T+ + + T AS + A A+K F FG S+ Sbjct: 371 PAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGI---NSV 427 Query: 1093 PSASVFVLGRTEEKQQEPVTSTSLVFGK---KADNEEPKCQPVFSFGNSEQTKDENSSKS 1149 S+SV T +P +FG A + P +F FG ++ + Sbjct: 428 SSSSVSTTTSTATAASQP-----FLFGAPQASAASFTPAMGSIFQFGKPPALPT-TTTVT 481 Query: 1150 TFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGG 1209 TFS S+ + A FG+ +T+A +++P +F N S+ + + P S+ Sbjct: 482 TFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAK 541 Query: 1210 GIFGSSTSSSNPPVATFVFGQ---SSNPV------SSSAFGNTAESSTSQSLLFSQDSKL 1260 S ++ P GQ ++ P SS FGN+A + + + K+ Sbjct: 542 SPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAAAPTPAPPSMIKI 601 Query: 1261 ATTSSTGTAVTPFVFGP--GASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPA 1318 + T + P G A T S FG A++ + GS+ VF G + S Sbjct: 602 VP-AHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSG--- 657 Query: 1319 FGAN-QTPTFGQSQ---GASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVF 1374 FGA QT + G S G++ P+P FG ++ P GS T SS+ F Sbjct: 658 FGATTQTASSGSSSSVFGSTTPSPFTFGGSAA-----PAGSGSFGINVATPGSSATTGAF 712 Query: 1375 GQQPSQSAFGSGT--------------------TPNSSSAFQF-------------GSST 1401 +FG+G T S+ F F G++T Sbjct: 713 -------SFGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTAT 765 Query: 1402 TNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGF-PFNQSPAAFTVGSNGKNV 1454 F +P GV T G++ S A+SA G G PF + +F++G+ K + Sbjct: 766 PTFGLNTPAP-GVGTSGSSLSFGASSAPAQGFVGVAPFGSAAPSFSIGAGSKTL 818 Score = 66.6 bits (161), Expect = 2e-10 Identities = 134/595 (22%), Positives = 209/595 (35%), Gaps = 96/595 (16%) Query: 496 TSSPSPINSSQALTNKVQMTSPSS-------TGSPMFK--FSSPIVKSTEANVLPPSSIG 546 TS+PSP Q+ Q TSPSS + SPMFK F++P E P S+ Sbjct: 277 TSAPSPA-PKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVS 335 Query: 547 FTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPAEILKEG 606 T + S ++ T +P+ SS PP PA K+ Sbjct: 336 ATAPSSSSLPTTTSTTAPTFQPVFSSMG--------------PPASVP---LPAPFFKQT 378 Query: 607 SVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDT 666 + +P +P +A+ +A +P+ P+ S S GFG + + SS T Sbjct: 379 TTP--ATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTT 436 Query: 667 CLLQNKVTDNKCIACQAAKLSPRDTAKQTGI-ETPNKSGKTTLSASGTGFGDKFKPVIGT 725 S A Q + P S + A G+ F P + T Sbjct: 437 --------------------STATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPT 476 Query: 726 WDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLG 785 T Q+ P A+ + + L + + S++ T + S+ + T + Sbjct: 477 TTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQP-TLTFSNTSTPTFNIP 535 Query: 786 FGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASS----------SSTVPV 835 FG K P+ S+ + + A + + PG++ PA + +S P Sbjct: 536 FGSSAKSPLPSYPGANPQPAFGAAE-------GQPPGAAKPALTPSFGSSFTFGNSAAPA 588 Query: 836 SLPSGGSLGLEKFKKPEGSWDCELCL--VQNKADSTKCLACESAKPGTKSGFKGFDTSSS 893 + P+ + K + + A K A P + G T+ Sbjct: 589 AAPTPAPPSMIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVF 648 Query: 894 SSNSAASSSFKFGVSSSSSGPSQTL---TSTGNFKFGDQGGFKIGVSSDSGSINPMSEGF 950 S +A SS F ++SSG S ++ T+ F F GG S S IN + G Sbjct: 649 SFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTF---GGSAAPAGSGSFGINVATPG- 704 Query: 951 KFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGL-SSGLSNPVSLTPFQFGVSNLGQEE 1009 S G F FG + + F GL + L TPF F V + E Sbjct: 705 -SSATTGAFSFGAGQSG------STATSTPFAGGLGQNALGTTGQSTPFAFNVGS--TTE 755 Query: 1010 KKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS-ASVAPF 1063 K +++ F +TPAP + TS + SF + + VAPF Sbjct: 756 SKPVFGGTATPTFGL------NTPAPG--VGTSGSSLSFGASSAPAQGFVGVAPF 802 Score = 50.8 bits (120), Expect = 9e-06 Identities = 88/358 (24%), Positives = 137/358 (38%), Gaps = 71/358 (19%) Query: 1140 QTKDENSSKSTFSFSMTKPSEKES---EQPAKATFAFGAQTSTTADQGAAKPVFSFLNNS 1196 Q ++ S ++ S + T P + S PA A A T+ + P+ L Sbjct: 133 QALEDKSDAASNSVTETPPITQPSFTFTLPAAAP----ASPPTSLLAPSTNPLLESLKKM 188 Query: 1197 SSSSSTPATSAGGGIFGSSTSSSNPP-----VATFVFGQSSNP--VSSSAFGNTAESST- 1248 + S P G ++T + +PP + QS P + S +F + ++ Sbjct: 189 QTPPSLPPCPESAG--AATTEALSPPKTPNLLPPLGLSQSGPPGLLPSPSFDSNPPTTLL 246 Query: 1249 ----SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSF 1304 + S++ + D+K T T P ++ + F FG TS S+ ++ Sbjct: 247 GLIPAPSMVPATDTKAPPTLQAETTTKPQAT---SAPSPAPKQSFLFGTQNTSPSSPAA- 302 Query: 1305 VFGTGPSAPSASPAFGANQT-PTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFG 1363 P+A SASP F T P + +G + P P + SS++L PT + PTF Sbjct: 303 -----PAASSASPMFKPIFTAPPKSEKEGPTPPGPSVSATAPSSSSL-PTTTSTTAPTFQ 356 Query: 1364 TVSSSSQPPV-------FGQQPSQSAFGSGTT---------------------PNSSS-- 1393 V SS PP F +Q + A TT P++ S Sbjct: 357 PVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSAS 416 Query: 1394 --AFQFG------SSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPA 1443 AF FG SS + T + S F FGA ++ AAS P+ F F + PA Sbjct: 417 KPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQAS-AASFTPAMGSIFQFGKPPA 473 >gi|161016767 mucin 21 [Homo sapiens] Length = 566 Score = 90.5 bits (223), Expect = 1e-17 Identities = 107/441 (24%), Positives = 181/441 (41%), Gaps = 42/441 (9%) Query: 1018 SSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPA 1077 +S + G+ VI+S + A +S S + TI S + + T+ E Sbjct: 27 TSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNS----EFHT 82 Query: 1078 TKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGN 1137 T G S S S+ + + +E TS+ +++ P + + Sbjct: 83 TSSGISTATNSEFSTVSSGISIATNSESS----TTSSGASTATNSESSTPSSGASTATNS 138 Query: 1138 SEQTKDENSSKSTFSFSMTKPSEKESEQPAKA-TFAFGAQTSTTADQGAAKPVFSFLNNS 1196 T +S +T S S T SE + +++ T + GA T+T ++ S NS Sbjct: 139 DSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNS 198 Query: 1197 SSS-----------SSTPATSAGGGIFGSSTSSSNPPVA-TFVFGQSSNPVSSSAFGNTA 1244 SS S + TS G G +S SS+ A T +SS P S + + Sbjct: 199 ESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNS 258 Query: 1245 ESSTSQSLLFSQDSKLATTSSTGTAV-------TPFVFGPGASSNNTTTSGFGFGATTTS 1297 ESST+ S + + ++T S+G + TP A+++ ++T+ G T S Sbjct: 259 ESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNS 318 Query: 1298 SSAGSSFVFGTGPSAPSASPAFGAN---QTPTFGQSQGASQPNPPGFGSISSSTALFPTG 1354 S+ +S T ++ S++ + GA+ + + S GAS G + SS T+ T Sbjct: 319 DSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTST-ATN 377 Query: 1355 SQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGV 1414 S+ + TVSS + + + S+ S T + SS G+ST NS S Sbjct: 378 SESS-----TVSSGASTATTSESSTTSSGASTATNSESSTVSSGAST-----ATNSESST 427 Query: 1415 FTFGANSSTPAASAQPSGSGG 1435 + GAN++T + S+ S G Sbjct: 428 TSSGANTATNSGSSVTSAGSG 448 Score = 86.7 bits (213), Expect = 2e-16 Identities = 109/449 (24%), Positives = 187/449 (41%), Gaps = 59/449 (13%) Query: 986 SSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENK 1045 SSG+S + T +F + G ++S+G S T +STP+ + T+ + Sbjct: 84 SSGIS---TATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDS 140 Query: 1046 SSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEE 1105 S+ + G ++ + + + S A E T G S +S S+ +E Sbjct: 141 STTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSES 200 Query: 1106 KQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQ 1165 ST A N E + S G T NS ST S + + ES Sbjct: 201 STTSSGAST-------ATNSESRTT---SNGAGTAT---NSESSTTSSGASTATNSESST 247 Query: 1166 PAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSS-NPPVA 1224 P+ GA T+T NS SS+ TS+G G +S SS+ + ++ Sbjct: 248 PSS-----GAGTAT---------------NSESST----TSSGAGTATNSESSTVSSGIS 283 Query: 1225 TFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNT 1284 T +SS P S + +ESST+ S + + ++T+S+G + A+++ + Sbjct: 284 TVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGAST--------ATNSES 335 Query: 1285 TTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSI 1344 +T+ G T S S+ +S T ++ S++ + G + T T +S S S Sbjct: 336 STTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTS-TATNSESSTVSSGASTATTSE 394 Query: 1345 SSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNF 1404 SS+T+ +G+ A + + SS + S ++ G+ T NS GSS T+ Sbjct: 395 SSTTS---SGASTATNSESSTVSSGASTATNSESSTTSSGANTATNS------GSSVTSA 445 Query: 1405 NFTNNSPSGVFTFGANSSTPAASAQPSGS 1433 + +G+ T ++ST + A+P GS Sbjct: 446 GSGTAALTGMHTTSHSASTAVSEAKPGGS 474 Score = 81.6 bits (200), Expect = 5e-15 Identities = 102/428 (23%), Positives = 177/428 (41%), Gaps = 59/428 (13%) Query: 1041 TSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVL 1100 ++E +S N G+ S + S A T G S + +S+ S V ++ Sbjct: 24 SNETSTSANTGSSVISSGA--------STATNSGSSVTSSGVSTATISGSSVTSNGVSIV 75 Query: 1101 GRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSE 1160 +E ST A N E FS +S + NS ST S + + Sbjct: 76 TNSEFHTTSSGIST-------ATNSE------FSTVSSGISIATNSESSTTSSGASTATN 122 Query: 1161 KESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSN 1220 ES P+ GA T+T +D ++++SS ++ AT++ SST+SS Sbjct: 123 SESSTPSS-----GASTATNSD-----------SSTTSSGASTATNSD-----SSTTSSE 161 Query: 1221 PPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGAS 1280 AT +SS S ++ +ESST S + + ++T+S+G + A+ Sbjct: 162 ASTATN--SESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGAST--------AT 211 Query: 1281 SNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGA-----NQTPTFGQSQGASQ 1335 ++ + T+ G G T S S+ +S T ++ S++P+ GA +++ T G + Sbjct: 212 NSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTAT 271 Query: 1336 PNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAF 1395 + S ST S P+ +S S G + ++ S T+ +S+A Sbjct: 272 NSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTAT 331 Query: 1396 QFGSSTTN--FNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKN 1453 SSTT+ + NS S + GA+++T + S+ S N + + G++ Sbjct: 332 NSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTAT 391 Query: 1454 VFSSSGTS 1461 SS TS Sbjct: 392 TSESSTTS 399 Score = 76.6 bits (187), Expect = 2e-13 Identities = 113/462 (24%), Positives = 184/462 (39%), Gaps = 60/462 (12%) Query: 889 DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE 948 +T SS +S AS++ G S +SSG S T T +G+ V+S+ SI SE Sbjct: 32 NTGSSVISSGASTATNSGSSVTSSGVS-TATISGS-----------SVTSNGVSIVTNSE 79 Query: 949 GFKFSKPIGDFKFG-VSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQ 1007 S I S+ S + +S++ G S+ +N S TP G S Sbjct: 80 FHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTA-TNSESSTPSS-GASTATN 137 Query: 1008 EEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKT 1067 + ++S+G S T +ST + + T+ S+ + G ++ + + + Sbjct: 138 SDSS-----TTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRA 192 Query: 1068 SEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEP 1127 S A E T G S + S T + TS+ +++ P Sbjct: 193 STATNSESSTTSSGASTATNSESRTTSNGA----GTATNSESSTTSSGASTATNSESSTP 248 Query: 1128 KCQPVFSFGNSEQTKDE------NSSKSTFSFSMTKPSEKESEQPAK----------ATF 1171 + + T NS ST S ++ + ES P+ +T Sbjct: 249 SSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTT 308 Query: 1172 AFGAQTSTTADQGAAKPVFSFLNNSSSS-----------SSTPATSAGGGIF---GSSTS 1217 + GA T+T +D S NS SS S + TS+G GSST+ Sbjct: 309 SSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTT 368 Query: 1218 SSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS-LLFSQDSKLATTSSTGTAVTPFVFG 1276 SS AT +SS S ++ T+ESST+ S + +S+ +T SS + T Sbjct: 369 SSGTSTATN--SESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESS 426 Query: 1277 PGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPA 1318 +S NT T+ G++ TS+ +G++ + G ++ SAS A Sbjct: 427 TTSSGANTATNS---GSSVTSAGSGTAALTGMHTTSHSASTA 465 Score = 70.9 bits (172), Expect = 9e-12 Identities = 79/308 (25%), Positives = 140/308 (45%), Gaps = 21/308 (6%) Query: 1170 TFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFG 1229 T + G T+T ++ S NS SS+++ S SST SS AT Sbjct: 82 TTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNS-ESSTPSSGASTATN--S 138 Query: 1230 QSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV-------TPFVFGPGASSN 1282 SS S ++ ++SST+ S + + ++T+S+G + T A+++ Sbjct: 139 DSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNS 198 Query: 1283 NTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFG 1342 ++T+ G T S S +S GT ++ S++ + GA+ T T +S S Sbjct: 199 ESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGAS-TATNSESSTPSSGAGTATN 257 Query: 1343 SISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTT 1402 S SS+T+ +G+ A + + SS V + S + G+ T NS S+ ++++ Sbjct: 258 SESSTTS---SGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESS----TTSS 310 Query: 1403 NFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSF 1462 N NS S + GA+++T + S+ S SG S ++ T S+G + ++SG+S Sbjct: 311 GANTATNSDSSTTSSGASTATNSESSTTS-SGASTATNSESSTT--SSGASTATNSGSST 367 Query: 1463 SGRKIKTA 1470 + TA Sbjct: 368 TSSGTSTA 375 Score = 34.3 bits (77), Expect = 0.91 Identities = 67/312 (21%), Positives = 102/312 (32%), Gaps = 19/312 (6%) Query: 643 SSFS--SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETP 700 S FS SSGI + ++ S+ N + A S T Sbjct: 93 SEFSTVSSGISIATNSES-STTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTAT 151 Query: 701 NKSGKTTLSASGTGFGDKFKPVIG----TWDCDTCLVQNKPEAIKCVACETPKPGTCVKR 756 N TT S + T + + ++ V ++ T G Sbjct: 152 NSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTAT 211 Query: 757 ALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSC 816 S A T T S SS T + + + P + S+ + Sbjct: 212 NSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTAT 271 Query: 817 MSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST-----KC 871 SE SS +S STV S S S G E S +DS+ Sbjct: 272 NSE---SSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGAS 328 Query: 872 LACESAKPGTKSGFK-GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQG 930 A S T SG ++ SS+++S AS++ G S++SSG T T+T + Sbjct: 329 TATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSG---TSTATNSESSTVSS 385 Query: 931 GFKIGVSSDSGS 942 G +S+S + Sbjct: 386 GASTATTSESST 397 >gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens] Length = 987 Score = 88.6 bits (218), Expect = 4e-17 Identities = 149/594 (25%), Positives = 220/594 (37%), Gaps = 128/594 (21%) Query: 823 SSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKP--- 879 SS+P ++S+T P P S+G P S L K +T A + P Sbjct: 493 SSLPTTTSTTAPTFQPVFSSMG------PPAS--VPLPAPFFKQTTTPATAPTTTAPLFT 544 Query: 880 ---GTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGV 936 S ++S S++SA+ +F FG++S SS T TST F G Sbjct: 545 GLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTAT---AASQPFLFGA 601 Query: 937 SSDSGSINPMSEGFKFSKPIGD-FKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSL 995 P + F+ +G F+FG KP + + F L + + S Sbjct: 602 --------PQASAASFTPAMGSIFQFG-----KPPALPTTTTVTTFSQSLPTAVPTATS- 647 Query: 996 TPFQFGVSNLGQEEKKEELPKSSSAGFS-FGTGVINSTPAPANTIVTSENKSSFNLGTIE 1054 SS+A FS FG+ + S PA ++ + + +S I Sbjct: 648 ---------------------SSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIP 686 Query: 1055 TKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPS-ASVFVLGRTEEKQQE--PV 1111 S++ +P + A +G G +PA PS S F G + P Sbjct: 687 FGSSAKSPLPSYPGANPQPAFGAAEGQPP-GAAKPALTPSFGSSFTFGNSAAPAPATAPT 745 Query: 1112 TSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATF 1171 + + + QP F ++ S F T Sbjct: 746 PAPASTIKIVPAHVPTPIQPTFG----------GATHSAFGLKATAS------------- 782 Query: 1172 AFGAQTSTTADQGAAKPVFSFLNNSSS----SSSTPATSAGGGIFGSSTSSSNPPVATFV 1227 AFGA S+ G + VFSF +SS ++ T ++ + +FGS+T S F Sbjct: 783 AFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSP------FT 836 Query: 1228 FGQSSNPVSSSAFG-NTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTT 1286 FG S+ P S +FG N A +S ATT + F FG G S + T+ Sbjct: 837 FGGSAAPAGSGSFGINVATPGSS-----------ATTGA-------FSFGAGQSGSTATS 878 Query: 1287 SGF--GFGATTTSSSAGSS-FVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGS 1343 + F G G ++ S+ F F G S + P FG TPTFGQ+ A PG G+ Sbjct: 879 TPFTGGLGQNALGTTGQSTPFAFNVG-STTESKPVFGGTATPTFGQNTPA-----PGVGT 932 Query: 1344 ISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGT-TPNSSSAFQ 1396 S S+ F S PA G S P F + G+G+ TP + Q Sbjct: 933 -SGSSLSFGASSAPAQGFVGVGPFGSAAPSF-------SIGAGSKTPGARQRLQ 978 Score = 85.5 bits (210), Expect = 3e-16 Identities = 139/501 (27%), Positives = 195/501 (38%), Gaps = 138/501 (27%) Query: 1064 TCKTSEAKKEEMPATKGGFSFG--NVEPAS--LPSAS--------VFVLGRTEEKQQEP- 1110 T +A PA K F FG N P+S P+AS +F EK+ Sbjct: 421 TATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTP 480 Query: 1111 ----VTST---SLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKES 1163 VT+T S P QPVFS S S + P K++ Sbjct: 481 PGPSVTATAPSSSSLPTTTSTTAPTFQPVFS-----------SMGPPASVPLPAPFFKQT 529 Query: 1164 EQPA--------------KATFAFGAQTSTT-ADQGAAKPVFSFLNNSSSSSSTPATSAG 1208 PA AT A TS + + A+KP F F NS SSSS T++ Sbjct: 530 TTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTS- 588 Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGT 1268 ++T++S P F+FG P +S+A A S Q F + L TT++ T Sbjct: 589 -----TATAASQP----FLFGA---PQASAASFTPAMGSIFQ---FGKPPALPTTTTVTT 633 Query: 1269 AVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSS--------------FVFGTGPSAPS 1314 +++++ GFG+T +S+ +S F G SA S Sbjct: 634 FSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKS 693 Query: 1315 ASPAF-GANQTPTFG----QSQGASQPN-PPGFGS---ISSSTALFP-TGSQPAP----- 1359 P++ GAN P FG Q GA++P P FGS +S A P T PAP Sbjct: 694 PLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIK 753 Query: 1360 -----------PTFGTVSSS---------------SQPPVFGQQPSQSAFGSGTTPNSSS 1393 PTFG + S S P FG + +FG+ T+ + Sbjct: 754 IVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGA 813 Query: 1394 AFQF---GSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFN-------QSPA 1443 Q GSS++ F T SP FTFG SA P+GSG F N + Sbjct: 814 TTQTASSGSSSSVFGSTTPSP---FTFG-------GSAAPAGSGSFGINVATPGSSATTG 863 Query: 1444 AFTVGSNGKNVFSSSGTSFSG 1464 AF+ G+ G++ +++ T F+G Sbjct: 864 AFSFGA-GQSGSTATSTPFTG 883 Score = 71.6 bits (174), Expect = 5e-12 Identities = 113/472 (23%), Positives = 185/472 (39%), Gaps = 76/472 (16%) Query: 1033 PAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASL 1092 PAP T+ + + T AS + A A+K F FG S+ Sbjct: 522 PAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGI---NSV 578 Query: 1093 PSASVFVLGRTEEKQQEPVTSTSLVFGK---KADNEEPKCQPVFSFGNSEQTKDENSSKS 1149 S+SV T +P +FG A + P +F FG ++ + Sbjct: 579 SSSSVSTTTSTATAASQP-----FLFGAPQASAASFTPAMGSIFQFGKPPALPT-TTTVT 632 Query: 1150 TFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGG 1209 TFS S+ + A FG+ +T+A +++P +F N S+ + + P S+ Sbjct: 633 TFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAK 692 Query: 1210 GIFGSSTSSSNPPVATFVFGQ---SSNPVSSSAFGN--TAESSTSQSLLFSQDSKLATTS 1264 S ++ P GQ ++ P + +FG+ T +S + + + A+T Sbjct: 693 SPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTI 752 Query: 1265 STGTAVTPFVFGP---GASSN----NTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASP 1317 A P P GA+ + T S FG A++ + GS+ VF G + S Sbjct: 753 KIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSG-- 810 Query: 1318 AFGAN-QTPTFGQSQ---GASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPV 1373 FGA QT + G S G++ P+P FG ++ P GS T SS+ Sbjct: 811 -FGATTQTASSGSSSSVFGSTTPSPFTFGGSAA-----PAGSGSFGINVATPGSSATTGA 864 Query: 1374 FGQQPSQSAFGSGTTPNSSS----------------------AFQFGSSTTNF------- 1404 F +FG+G + ++++ AF GS+T + Sbjct: 865 F-------SFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTA 917 Query: 1405 --NFTNNSPS-GVFTFGANSSTPAASAQPSGSGGF-PFNQSPAAFTVGSNGK 1452 F N+P+ GV T G++ S A+SA G G PF + +F++G+ K Sbjct: 918 TPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAPSFSIGAGSK 969 Score = 65.9 bits (159), Expect = 3e-10 Identities = 203/927 (21%), Positives = 298/927 (32%), Gaps = 204/927 (22%) Query: 436 NGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEIT 495 N S G G+ R+ + + + S+ E++ +P P++ IT+ L +S + Sbjct: 226 NSNSQSTPGSSGQ-RKRKVQLLPSR--RGEQLTLPPPPQLGYSITAEDLDLEKKASLQWF 282 Query: 496 TSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAK 555 + + S A +N V T P T P F F+ P A PP+S+ + P+ + Sbjct: 283 NQALE--DKSDAASNSVTETPP--TTQPSFTFTLP----AAATASPPTSLLAPSTNPLLE 334 Query: 556 TAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPAEILKEGSVLDILKSP 615 + + + +L P S+ T + + KTP P L + +L SP Sbjct: 335 SLKKMQTPPSLPPCPESAG--AATTEALSPPKTP------SLLPPLGLSQSGPPGLLPSP 386 Query: 616 GFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTD 675 F S ++ A S V T KA + Q +T Sbjct: 387 SFDSKPPTTLLGLIPAPSMVPAT----------------DTKAPPTLQAETATKPQ---- 426 Query: 676 NKCIACQAAKLSPRDTAKQTGI-ETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQ 734 A +P KQ+ + T N S + + + + FKP+ T + Sbjct: 427 --------ATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIF------TAPPK 472 Query: 735 NKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPI 794 ++ E TP PG V T T S S+ T S+++ T +P+ Sbjct: 473 SEKEG------PTP-PGPSV----TATAPSSSSLPTTTSTTAPTF------------QPV 509 Query: 795 GSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASS----SSTVPVSLPSGGSLGLEKFKK 850 S S P +SVP + +T P + P+ Sbjct: 510 FS---------------------SMGPPASVPLPAPFFKQTTTPATAPT----------- 537 Query: 851 PEGSWDCELCLVQNKADSTKCLA-CESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSS 909 L A +T +A SA P T S A+ +F FG++S Sbjct: 538 ------TTAPLFTGLASATSAVAPITSASPSTDS--------------ASKPAFGFGINS 577 Query: 910 SSSGPSQTLTSTGN-----FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIG---DFKF 961 SS T TST F FG + GSI F+F KP Sbjct: 578 VSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSI------FQFGKPPALPTTTTV 631 Query: 962 GVSSESKPEEV---KKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQ--------EEK 1010 S+S P V S D FG + S P + + SN Sbjct: 632 TTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSA 691 Query: 1011 KEELPKSSSAGFSFGTGVI-NSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSE 1069 K LP A G P A +T SSF G + + AP S Sbjct: 692 KSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPAST 751 Query: 1070 AKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEP-- 1127 K + PA +P+ G + +T+ FG A ++ Sbjct: 752 IK---------------IVPAHVPTPIQPTFGGATH-SAFGLKATASAFGAPASSQPAFG 795 Query: 1128 KCQPVFS--------FGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTST 1179 VFS FG + QT SS S F + P + +FG +T Sbjct: 796 GSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVAT 855 Query: 1180 TADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSA 1239 A FSF S S++T GG G + + F F S S Sbjct: 856 PG-SSATTGAFSFGAGQSGSTATSTPFTGG--LGQNALGTTGQSTPFAFNVGSTTESKPV 912 Query: 1240 FGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSS 1299 FG TA + Q+ T + G + GASS GF S Sbjct: 913 FGGTATPTFGQN-----------TPAPGVGTSGSSLSFGASS----APAQGFVGVGPFGS 957 Query: 1300 AGSSFVFGTGPSAPSASPAFGANQTPT 1326 A SF G G P A A + T Sbjct: 958 AAPSFSIGAGSKTPGARQRLQARRQHT 984 Score = 58.9 bits (141), Expect = 3e-08 Identities = 141/619 (22%), Positives = 224/619 (36%), Gaps = 126/619 (20%) Query: 887 GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946 G + +S+ S F +S P+ + G+ K G + S +N Sbjct: 70 GQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRG------LNSQSSDDHLNKR 123 Query: 947 SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSS-GLSNPVSLTPFQFGVSNL 1005 S S G + G+ S S+ S G+S N S +PF S+ Sbjct: 124 SRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTR----GISQLWKRNGPSSSPFSSPASSR 179 Query: 1006 GQEEKK-------EELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSA 1058 Q ++ EEL SS+ STP A+ E + + ++ Sbjct: 180 SQTPERPAKKIREEELCHHSSS----------STPLAADKESQGEKAADTTPRKKQNSNS 229 Query: 1059 SVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVF 1118 P + + K + +P+ +G E +LP LG + +T+ L Sbjct: 230 QSTPGSSGQRKRKVQLLPSRRG-------EQLTLPPPPQ--LGYS-------ITAEDLDL 273 Query: 1119 GKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKES---EQPAKATFAFGA 1175 KKA S Q ++ S ++ S + T P+ + S PA AT A Sbjct: 274 EKKA-----------SLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAAT----A 318 Query: 1176 QTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVF-----GQ 1230 T+ + P+ L + S P G ++T + +PP + Q Sbjct: 319 SPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAG--AATTEALSPPKTPSLLPPLGLSQ 376 Query: 1231 SSNP--VSSSAFGNTAESST-----SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNN 1283 S P + S +F + ++ + S++ + D+K T TA P ++ + Sbjct: 377 SGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQAT---SAPSP 433 Query: 1284 TTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQT-PTFGQSQGASQPNPPGFG 1342 F FG TS S+ ++ P+A SASP F T P + +G + P P Sbjct: 434 APKQSFLFGTQNTSPSSPAA------PAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTA 487 Query: 1343 SISSSTALFPTGSQPAPPTFGTVSSSSQPPV-------FGQQPSQSAFGSGTT------- 1388 + SS++L PT + PTF V SS PP F +Q + A TT Sbjct: 488 TAPSSSSL-PTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGL 546 Query: 1389 --------------PNSSS----AFQFG------SSTTNFNFTNNSPSGVFTFGANSSTP 1424 P++ S AF FG SS + T + S F FGA ++ Sbjct: 547 ASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQAS- 605 Query: 1425 AASAQPSGSGGFPFNQSPA 1443 AAS P+ F F + PA Sbjct: 606 AASFTPAMGSIFQFGKPPA 624 >gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo sapiens] Length = 2036 Score = 86.7 bits (213), Expect = 2e-16 Identities = 301/1457 (20%), Positives = 491/1457 (33%), Gaps = 166/1457 (11%) Query: 69 STDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTR 128 S D P ++ D S I+ G + +T +P + ++ + Sbjct: 73 SPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRS 132 Query: 129 PSLHRSHLNFSML------ESPALHCQPSTS--SAFPIGSSGFSLVKEIKDSTSQHDDDN 180 P +HL SM ES H +P ++ +AFP ++ L +E ST+ H Sbjct: 133 PDT--THLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQE---STASH---- 183 Query: 181 ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS 240 S D T+S ++ PE HS T T+ N +A G L Sbjct: 184 --------SSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPD--NTTASGLLE 233 Query: 241 PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS 300 S+ S ++ SP G TT G + AP + S S Sbjct: 234 ASMPVHSSTRSPHTTLSP--AGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTS 291 Query: 301 YGVTSS------TARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKR 354 +G SS +AR L + S+ + + P + G + T + Sbjct: 292 HGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSST 351 Query: 355 EKVDSQYPPVQRLMTPKPVSI----ATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEK 410 S P + +P S + + +F S T SG ++ ++ +TG Sbjct: 352 THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATG--- 408 Query: 411 NMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVP 470 LPA + S +G + P+ ME Sbjct: 409 ------------------TIVLPARSTTSVLLGES------------TTSPISSGSMETT 438 Query: 471 VLP-KISLPITSSSLPTFNFS--SPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKF 527 LP + P S TF+ S SP T S S +S + + + P ST + F Sbjct: 439 ALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPD 498 Query: 528 SSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSS--STLEPIISSSAHHVTTVNSTNC 585 S+ + + SS G T + + + SG S ST S S + ST Sbjct: 499 STTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTA 558 Query: 586 KKTPPEDCEGPFRPAEILKEGSVLDILKSPGF--ASPKIDSVAAQPTAT-SPVVYTRPAI 642 E P D S G AS ++ S P T SP T P + Sbjct: 559 LSFGQESTTFHSNPGST-HTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL 617 Query: 643 SSFSSSGIGFGESLKAGSSWQCD-TCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPN 701 S++ S S T ++ T ++ P + T Sbjct: 618 QGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASST------TSG 671 Query: 702 KSGKTTL-----SASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKR 756 S K+T+ ASGT G + T + I + T PG + Sbjct: 672 HSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPG--LSE 729 Query: 757 ALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSC 816 A T S + T T S +S T +LG G++ + VS + +S Sbjct: 730 ASTTFYSSPRSPTTTLSPASMT----SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSE 785 Query: 817 MSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACES 876 S SS S+ +TV + G E L + ++ + Sbjct: 786 ESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEEST 845 Query: 877 AKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQT-LTSTGNFKFGDQGGFKIG 935 A PG+ + + ++ ++ S F SS S+G + ST + G+ ++ Sbjct: 846 AFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLS 905 Query: 936 VSSD----------SGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGL 985 SS + S++ S F S D ++ + V ++S + + G Sbjct: 906 PSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS-SGVSEESSTSHSQPGS 964 Query: 986 SSGLSNPVSLTPFQFG----VSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVT 1041 + + P S T S+ Q + L S+ S G +P +T T Sbjct: 965 THTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETT 1024 Query: 1042 SENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPA--TKGGFSFGNVEPASLPSASVFV 1099 + G +E + P T PA T G + S PS+S Sbjct: 1025 LLPDDTITSGLVEAST----PTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSS--- 1077 Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPS 1159 + P T+ + V + P P F S T + +T S Sbjct: 1078 ----DTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSS----- 1128 Query: 1160 EKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSS 1219 A F + TS + P+ S S+ +++ P ++ G+ ST+ Sbjct: 1129 ---PGATGTALFPTRSATSVLVGEPTTSPISS---GSTETTALPGSTTTAGLSEKSTTFY 1182 Query: 1220 NPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGA 1279 + P + + +P S+++ G + ES+TS S + TT+ G+ P V Sbjct: 1183 SSPRSP---DTTLSPASTTSSGVSEESTTSHS----RPGSTHTTAFPGSTTMPGV----- 1230 Query: 1280 SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQT---PTFGQSQGASQP 1336 S +T S G+T T+ S GS+ GP + + + G+ +T P + G + Sbjct: 1231 -SQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEA 1289 Query: 1337 NPPGFGSISS-STALFPTGS---QPAPPTFGTVSSSSQ----PPVFGQQPSQSAFGSGTT 1388 + P S S T L P GS Q TF + SS PP + + S + Sbjct: 1290 STPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGS 1349 Query: 1389 PNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVG 1448 P+S+ F +S+T + S + + A ++TP S S + G + + G Sbjct: 1350 PSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTP--SPARSTTSGLVEESTAYHSSPG 1407 Query: 1449 SNGKNVFSSSGTSFSGR 1465 S F S T+ SGR Sbjct: 1408 STQTMHFPESSTA-SGR 1423 Score = 78.2 bits (191), Expect = 6e-14 Identities = 261/1252 (20%), Positives = 444/1252 (35%), Gaps = 153/1252 (12%) Query: 256 DSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSL 315 +S + G TT+ ++ + L +T Y + + + + S ++ S Sbjct: 15 ESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSP 74 Query: 316 EKMSSPLADAKRIPSI-VSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVS 374 + M++ + A PS+ V SP+ ++ T K P + T S Sbjct: 75 DAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTK-----PGLSEKSTTFYSS 129 Query: 375 IATNRSVYFKPSLTPSG---EFRKTNQRIDNKCSTGYEKNMT-PGQNREQRESGFSYPNF 430 + + + S+T SG E ++ R + +T + + T PG ++E S S P Sbjct: 130 PRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTAS-HSSPG- 187 Query: 431 SLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFS 490 P LS G + E T F S+P E +P S + +S+P + + Sbjct: 188 --PTDTTLSPG-STTASSLGPEYTTF-HSRPGSTETTLLPDNTTAS-GLLEASMPVHSST 242 Query: 491 SPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPS--SIGFT 548 TT SP+ + Q S + P K + P +T + + PS S G Sbjct: 243 RSPHTTLSPAGSTTRQG-------ESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSP 295 Query: 549 FSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDC-EGPFRPAEILKEGS 607 S+P T +S S+T + S+ +H ++ ST P D G + + Sbjct: 296 SSIP---TTHISARSTTSGLVEESTTYH-SSPGSTQTMHFPESDTTSGRGEESTTSHSST 351 Query: 608 VLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTC 667 I +P S ++ + ++ T SS +S G E A S Q T Sbjct: 352 THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTS---GRSEESTASHSSQDATG 408 Query: 668 LLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWD 727 + + + SP + P + LS T F Sbjct: 409 TIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTF------------ 456 Query: 728 CDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTV-VSESAETMTASSSSCTVTTGTLGF 786 + P + P T + A T + VSE + T + S T T F Sbjct: 457 ------HSSPRS----------PATTLSPASTTSSGVSEESTTSRSRPGS----THTTAF 496 Query: 787 GDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPG----SSVPASSSSTVPVSLPSGGS 842 D P S + S + D + + G S+ SSS + +L G + Sbjct: 497 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGST 556 Query: 843 LGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSS 902 L S+ E + ST F S++SS +S+ Sbjct: 557 TAL--------SFGQESTTFHSNPGSTHTTL--------------FPDSTTSSGIVEAST 594 Query: 903 FKFGVSSSSSGPSQTLTSTGNFKFGDQG---GFKIGVSSD-------SGSINPMSEGFKF 952 V SS+ P TL+ + G QG F+ +S S + P+ E + Sbjct: 595 ---RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTY 651 Query: 953 SKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKE 1012 + G S+ + + + K + + TP + G+ E Sbjct: 652 HRSPG------STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGE--- 702 Query: 1013 ELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKK 1072 S+++ S G+ I + P T SE ++F + + + +++P + TS Sbjct: 703 ----STTSRISPGSTEITTLPGSTTTPGLSEASTTF-YSSPRSPTTTLSPASM-TSLGVG 756 Query: 1073 EEMPATKG--GFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQ 1130 EE ++ G + V PAS + + T T T+ VF + Sbjct: 757 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETT-VFPHSTTTSVHGEE 815 Query: 1131 PVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVF 1190 P T ++ + + +T+ S PA A T TTAD G F Sbjct: 816 PTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPA-TLTTADLGEESTTF 874 Query: 1191 SFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQ 1250 + S+ + +PA S G+ G ST S P +T +P + S + +S+T Sbjct: 875 PSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSL---SEKSTTFY 931 Query: 1251 SLLFSQDSKL--ATTSSTGTA-------VTPFVFGPGASSNNTTTSGFGFGATTTSSSAG 1301 + S D+ L ATT+S+G + P A ++TTTS TT+ SS G Sbjct: 932 TSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQG 991 Query: 1302 SSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPT 1361 S+ P + +AS Q+ TF S G ++ +I+S T + + + Sbjct: 992 STEA-TLSPGSTTASSL--GQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGS 1048 Query: 1362 FGTVSSSSQPPVFGQQPSQSAF-----GSGTTPN--SSSAFQFGSSTTNFNFTNNSPSGV 1414 T + + G Q + F S TTP+ ++A STT + +++P+ Sbjct: 1049 LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTH 1108 Query: 1415 F-----TFGANSSTPAASAQPSGSGGFPF-NQSPAAFTVGSNGKNVFSSSGT 1460 F T G + + + P +G F +S + VG + SS T Sbjct: 1109 FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGST 1160 Score = 70.9 bits (172), Expect = 9e-12 Identities = 284/1342 (21%), Positives = 457/1342 (34%), Gaps = 171/1342 (12%) Query: 93 SSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPST 152 S+ T + EP ++ ST +T ++PD T RS ES A H Sbjct: 357 SAPSTTSALVEEPTSYHSSPGSTATT--HFPDSSTTSG--RSE------ESTASHSSQDA 406 Query: 153 SSAFPIGSSGFSLVKEIKDSTSQHDDDNISTT----SGFSSRASDKDITVSKNTSLPPLW 208 + + + + V + +TS ++ TT S + S++ T + P Sbjct: 407 TGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATT 466 Query: 209 -SPEAERSHSLSQHTATSSKKP-AFNLSAF--GTLSPSLGNSSILKTSQLG--DSPFYPG 262 SP + S +S+ + TS +P + + +AF T +P L S S G D+ P Sbjct: 467 LSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 526 Query: 263 KTTYGG----AAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLEKM 318 TT G + + S +T + Q S + ST + Sbjct: 527 STTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTS 586 Query: 319 SSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVSIATN 378 S + + R+ S SP + S T + E Q P TP P S AT Sbjct: 587 SGIVEASTRVHSSTGSPRTTLSPASS---TSPGLQGESTAFQTHPASTHTTPSPPSTAT- 642 Query: 379 RSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGL 438 P E ++ + +T + + T + E+ S P+ S + Sbjct: 643 ---------APVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSA 693 Query: 439 SSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSS 498 S G G + + E+ LP + S T +SSP T++ Sbjct: 694 HSTTSGRGES---------TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTT 744 Query: 499 PSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAE 558 SP + + + TS S GS T + V P S+ T Sbjct: 745 LSPASMTSLGVGEESTTSRSQPGS------------THSTVSPASTT----------TPG 782 Query: 559 LSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPAE----ILKEGSVLDILKS 614 LS S+T+ S +ST E RPA + E S L Sbjct: 783 LSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTE 842 Query: 615 PGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVT 674 A P P +T + PA + +++ +G + SS T L + T Sbjct: 843 ESTAFP------GSPASTQTGL---PA--TLTTADLGEESTTFPSSSGSTGTKLSPARST 891 Query: 675 DNKCIA-CQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLV 733 + + ++LSP T T P +LS T F + T T Sbjct: 892 TSGLVGESTPSRLSPSSTETTT---LPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 948 Query: 734 QNKPEAIKCVACETPKPGTCVKRALT-LTVVSESAETMTASSSSCTVTTGTLGFGDKFKR 792 E + +PG+ A T S+ ++ T S SS T TL G Sbjct: 949 SGVSEES---STSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTAS 1005 Query: 793 PIGSWECSVCCVSNNAE-----DNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEK 847 +G + + E D+ S + E + ++ S ++ S S GL++ Sbjct: 1006 SLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQE 1065 Query: 848 FKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGV 907 SW + +D+T +A P S SS+ + ++SS G Sbjct: 1066 ESTTFQSWP-------SSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGR 1118 Query: 908 SSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSK--PIGDFKFGVSS 965 S S+ + +TG F + + V + S P+S G + P G+S Sbjct: 1119 SEESTTVHSSPGATGTALFPTRSATSVLVGEPTTS--PISSGSTETTALPGSTTTAGLSE 1176 Query: 966 ESKPEEVKKDSKNDNFKFG--LSSGLSNPVSLTPFQFGVSNLGQEEKKEELP---KSSSA 1020 +S S + SSG+S + + + G ++ +P + S+A Sbjct: 1177 KSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTA 1236 Query: 1021 GFSFGTGVINSTPAPANTIVTSENKSSFNL----GTIETKSASVAPFTCKTSEAKKEEMP 1076 S G ++T +P +T +S S G+ ET ++ P S + P Sbjct: 1237 SHS-SPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTET---TLLPDNTTASGLLEASTP 1292 Query: 1077 ATKGGFSFGNVEPASLPSASVFVLGRTEEKQQ----------EPVTSTSLVFGKKADNEE 1126 S G+ P+ S G + Q P T+++ V + Sbjct: 1293 VHS---STGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGS 1349 Query: 1127 PKCQPVFSFGNSEQTKDENSSKSTFSFS----MTKPSEKES-------EQPAKATFAFGA 1175 P P F S T + +T S T PS S E A + Sbjct: 1350 PSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGST 1409 Query: 1176 QT-----STTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQ 1230 QT S+TA + + S + + + SS P+T++ +S SS +AT F Sbjct: 1410 QTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHF-- 1467 Query: 1231 SSNPVSSSAFGNTAESSTSQSLLFSQDSK-------LATTSSTGTAVTPFVFGPGAS--- 1280 P SS+ G + ES+ S S S D+ TTS T F PG+ Sbjct: 1468 ---PESSTTSGRSEESTASHS---SPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETT 1521 Query: 1281 -SNNTTTSGFGFGATT--TSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPN 1337 ++ TT G +T TS G F PS P+ + F A+ + + + + Sbjct: 1522 LASTATTPGLSAKSTILYTSDLVGEPTTFYISPS-PTYTTLFPASSSTSGLTEESTTFHT 1580 Query: 1338 PPGFGSISSSTALFPTGSQPAP 1359 P F S ST T + P Sbjct: 1581 SPSFTSTIVSTESLETLAPETP 1602 Score = 52.0 bits (123), Expect = 4e-06 Identities = 108/497 (21%), Positives = 190/497 (38%), Gaps = 59/497 (11%) Query: 1003 SNLGQEEKKEELPKSSSAGFSFGTGVINSTP-APANTIVTSENKSSFNLGTIETKSASVA 1061 S+LG E S+ +G S + +S+P A A T++ + + S +G ++ + Sbjct: 44 SSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVG-----DSTPS 98 Query: 1062 PFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKK 1121 P + + E TK G S + S P R+ + P + TS ++ Sbjct: 99 PISSGSMETTALPGSTTKPGLSEKSTTFYSSP--------RSPDTTHLPASMTSSGVSEE 150 Query: 1122 A--DNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTST 1179 + + P +F S T S +ST S S P++ + + G + +T Sbjct: 151 STTSHSRPGSTHTTAFPGST-TMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTT 209 Query: 1180 TADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSN------ 1233 + + +N+++S A+ S ++ +P +T G+S+ Sbjct: 210 FHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPS 269 Query: 1234 --------PVSSSAF--GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSN- 1282 P ++SAF +T + S+ + S +TTS T + PG++ Sbjct: 270 SKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTM 329 Query: 1283 ----NTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSA----------SPAFGANQTPTFG 1328 + TTSG G +TT+ SS ++ + PS SA SP G+ T F Sbjct: 330 HFPESDTTSGRGEESTTSHSS--TTHTISSAPSTTSALVEEPTSYHSSP--GSTATTHFP 385 Query: 1329 QSQGASQPNPPGFGSISSSTALFPTGS--QPAPPTFGTV--SSSSQPPVFGQQPSQSAFG 1384 S S + S SS A TG+ PA T + S++ P G + + G Sbjct: 386 DSSTTSGRSEESTASHSSQDA---TGTIVLPARSTTSVLLGESTTSPISSGSMETTALPG 442 Query: 1385 SGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAA 1444 S TTP S S+ T SP+ + G + + + ++P + F S Sbjct: 443 STTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTT 502 Query: 1445 FTVGSNGKNVFSSSGTS 1461 + + SS G++ Sbjct: 503 PGLSRHSTTSHSSPGST 519 >gi|26051278 nuclear pore membrane protein 121 [Homo sapiens] Length = 984 Score = 84.3 bits (207), Expect = 8e-16 Identities = 142/595 (23%), Positives = 209/595 (35%), Gaps = 133/595 (22%) Query: 823 SSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKP--- 879 SS+P ++S+T P P S+G P S L K +T A + P Sbjct: 493 SSLPTTTSTTAPTFQPVFSSMG------PPAS--VPLPAPFFKQTTTPATAPTTTAPLFT 544 Query: 880 ---GTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGN-----FKFGDQGG 931 S ++S S++SA+ +F FG++S SS T TST F FG Sbjct: 545 GLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG---- 600 Query: 932 FKIGVSSDSGSINPMSEGFKFSKPIGD-FKFGVSSESKPEEVKKDSKNDNFKFGLSSGLS 990 P + F+ +G F+FG KP + + F L + + Sbjct: 601 ------------APQASAASFTPAMGSIFQFG-----KPPALPTTTTVTTFSQSLHTAVP 643 Query: 991 NPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFS-FGTGVINSTPAPANTIVTSENKSSFN 1049 S SS+A FS FG+ + S PA ++ + + +S Sbjct: 644 TATS----------------------SSAADFSGFGSTLATSAPATSSQPTLTFSNTSTP 681 Query: 1050 LGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPS-ASVFVLGRTEEKQQ 1108 I S++ +P + A +G G +PA PS S F G + Sbjct: 682 TFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQ-PPGAAKPALAPSFGSSFTFGNSAAPAA 740 Query: 1109 EPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAK 1168 P + + P+F ++ S F T Sbjct: 741 APTPAPPSMIKVVPAYVPTPIHPIFG----------GATHSAFGLKAT------------ 778 Query: 1169 ATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGG---GIFGSSTSSSNPPVAT 1225 AFGA S+ G + VF SS +T T++ G +FGS+T S Sbjct: 779 -ASAFGAPASSQPAFGGSTAVFFGAATSSGFGATTQTASSGSSSSVFGSTTPS------P 831 Query: 1226 FVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTT 1285 F FG S+ P S +FG T + T F FG G S + T Sbjct: 832 FTFGGSAAPAGSGSFGIN-----------------VATPGSSTTTGAFSFGAGQSGSTAT 874 Query: 1286 TSGF--GFGATTTSSSAGSS-FVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFG 1342 ++ F G G ++ S+ F F S + P FG TPTFG + A PG G Sbjct: 875 STPFAGGLGQNALGTTGQSTPFAFNVS-STTESKPVFGGTATPTFGLNTPA-----PGVG 928 Query: 1343 SISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGT-TPNSSSAFQ 1396 + S S+ F S PA G FG + G+G+ TP + Q Sbjct: 929 T-SGSSLSFGASSAPAQGFVGVAP-------FGSAALSFSIGAGSKTPGARQRLQ 975 Score = 83.6 bits (205), Expect = 1e-15 Identities = 138/471 (29%), Positives = 194/471 (41%), Gaps = 101/471 (21%) Query: 1064 TCKTSEAKKEEMPATKGGFSFG--NVEPAS--LPSAS--------VFVLGRTEEKQQEP- 1110 T +A PA K F FG N P+S P+AS +F EK+ Sbjct: 421 TATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSAPPMFKPIFTAPPKSEKEGPTP 480 Query: 1111 ----VTST---SLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKES 1163 VT+T S P QPVFS S S + P K++ Sbjct: 481 PGPSVTATAPSSSSLPTTTSTTAPTFQPVFS-----------SMGPPASVPLPAPFFKQT 529 Query: 1164 EQPA--------------KATFAFGAQTSTT-ADQGAAKPVFSFLNNSSSSSSTPATSAG 1208 PA AT A TS + + A+KP F F NS SSSS T++ Sbjct: 530 TTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTS- 588 Query: 1209 GGIFGSSTSSSNPPVATFVFG--QSSNPVSSSAFGNT-------AESSTSQSLLFSQDSK 1259 ++T++S P F+FG Q+S + A G+ A +T+ FSQ Sbjct: 589 -----TATAASQP----FLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLH 639 Query: 1260 LATTSSTGTAVTPFV-FGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPA 1318 A ++T ++ F FG +++ TS T S+++ +F G SA S P+ Sbjct: 640 TAVPTATSSSAADFSGFGSTLATSAPATSSQP--TLTFSNTSTPTFNIPFGSSAKSPLPS 697 Query: 1319 F-GANQTPTFG----QSQGASQPN-PPGFGSI-----SSSTALFPTGSQPAPPTFGTVSS 1367 + GAN P FG Q GA++P P FGS S++ A PT PAPP+ V Sbjct: 698 YPGANPQPAFGAAEGQPPGAAKPALAPSFGSSFTFGNSAAPAAAPT---PAPPSMIKVVP 754 Query: 1368 SSQP----PVFGQQPSQSAFGSGTTPNS-----SSAFQFGSSTTNFNFTNNSPSGVFTFG 1418 + P P+FG + SAFG T ++ SS FG ST F F + SG FG Sbjct: 755 AYVPTPIHPIFGGA-THSAFGLKATASAFGAPASSQPAFGGSTAVF-FGAATSSG---FG 809 Query: 1419 ANSSTPAASAQPSGSGG-----FPFNQSPAAFTVGSNGKNVFSSSGTSFSG 1464 A + T ++ + S G F F S A GS G NV + ++ +G Sbjct: 810 ATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSTTTG 860 Score = 67.4 bits (163), Expect = 1e-10 Identities = 113/473 (23%), Positives = 178/473 (37%), Gaps = 81/473 (17%) Query: 1033 PAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASL 1092 PAP T+ + + T AS + A A+K F FG S+ Sbjct: 522 PAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGI---NSV 578 Query: 1093 PSASVFVLGRTEEKQQEPVTSTSLVFGK---KADNEEPKCQPVFSFGNSEQTKDENSSKS 1149 S+SV T +P +FG A + P +F FG ++ + Sbjct: 579 SSSSVSTTTSTATAASQP-----FLFGAPQASAASFTPAMGSIFQFGKPPALPT-TTTVT 632 Query: 1150 TFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGG 1209 TFS S+ + A FG+ +T+A +++P +F N S+ + + P S+ Sbjct: 633 TFSQSLHTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAK 692 Query: 1210 GIFGSSTSSSNPPVATFVFGQ---SSNPV------SSSAFGNTAESSTSQSLLFSQDSKL 1260 S ++ P GQ ++ P SS FGN+A + + + K+ Sbjct: 693 SPLPSYPGANPQPAFGAAEGQPPGAAKPALAPSFGSSFTFGNSAAPAAAPTPAPPSMIKV 752 Query: 1261 ATTSSTGTAVTPFVFGPGASSN---NTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASP 1317 + T + P +FG S T S FG A++ + GS+ VF + S Sbjct: 753 VP-AYVPTPIHP-IFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVF----FGAATSS 806 Query: 1318 AFGAN-QTPTFGQSQ---GASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPV 1373 FGA QT + G S G++ P+P FG ++ P GS T SS+ Sbjct: 807 GFGATTQTASSGSSSSVFGSTTPSPFTFGGSAA-----PAGSGSFGINVATPGSSTTTGA 861 Query: 1374 FGQQPSQSAFGSGT--------------------TPNSSSAFQF-------------GSS 1400 F +FG+G T S+ F F G++ Sbjct: 862 F-------SFGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVSSTTESKPVFGGTA 914 Query: 1401 TTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGF-PFNQSPAAFTVGSNGK 1452 T F +P GV T G++ S A+SA G G PF + +F++G+ K Sbjct: 915 TPTFGLNTPAP-GVGTSGSSLSFGASSAPAQGFVGVAPFGSAALSFSIGAGSK 966 Score = 53.9 bits (128), Expect = 1e-06 Identities = 132/586 (22%), Positives = 206/586 (35%), Gaps = 79/586 (13%) Query: 496 TSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAK 555 TS+PSP Q+ Q TSPSS +P + P+ K PP S + P Sbjct: 428 TSAPSPA-PKQSFLFGTQNTSPSSPAAPAASSAPPMFKPIFT--APPKSEKEGPTPPGPS 484 Query: 556 TAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPAEILKEGSVLDILKSP 615 + SSS+L S++A V S+ PP PA K+ + +P Sbjct: 485 VTATAPSSSSLPTTTSTTAPTFQPVFSS---MGPPASVP---LPAPFFKQTTTP--ATAP 536 Query: 616 GFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTD 675 +P +A+ +A +P+ P+ S S GFG + + SS T Sbjct: 537 TTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTT--------- 587 Query: 676 NKCIACQAAKLSPRDTAKQTGI-ETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQ 734 S A Q + P S + A G+ F P + T T Q Sbjct: 588 -----------STATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQ 636 Query: 735 NKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPI 794 + A+ + + L + + S++ T + S+ + T + FG K P+ Sbjct: 637 SLHTAVPTATSSSAADFSGFGSTLATSAPATSSQP-TLTFSNTSTPTFNIPFGSSAKSPL 695 Query: 795 GSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASS----------SSTVPVSLPSGGSLG 844 S+ + + A + + PG++ PA + +S P + P+ Sbjct: 696 PSYPGANPQPAFGAAE-------GQPPGAAKPALAPSFGSSFTFGNSAAPAAAPTPAPPS 748 Query: 845 LEKFKKPEGSWDCELCL--VQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSS 902 + K + A K A P + G T + +A SS Sbjct: 749 MIKVVPAYVPTPIHPIFGGATHSAFGLKATASAFGAPASSQPAFGGST-AVFFGAATSSG 807 Query: 903 FKFGVSSSSSGPSQTL---TSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDF 959 F ++SSG S ++ T+ F F GG S S IN + G S G F Sbjct: 808 FGATTQTASSGSSSSVFGSTTPSPFTF---GGSAAPAGSGSFGINVATPG--SSTTTGAF 862 Query: 960 KFGVSSESKPEEVKKDSKNDNFKFGL-SSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSS 1018 FG + + F GL + L TPF F VS+ E K ++ Sbjct: 863 SFGAGQSG------STATSTPFAGGLGQNALGTTGQSTPFAFNVSS--TTESKPVFGGTA 914 Query: 1019 SAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS-ASVAPF 1063 + F +TPAP + TS + SF + + VAPF Sbjct: 915 TPTFGL------NTPAPG--VGTSGSSLSFGASSAPAQGFVGVAPF 952 Score = 53.5 bits (127), Expect = 1e-06 Identities = 143/607 (23%), Positives = 226/607 (37%), Gaps = 128/607 (21%) Query: 930 GGFKIGVSSDSGS--INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSS 987 G K G++S S +N S S G + G+ S S+ S G+S Sbjct: 105 GSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYASGIPSSSRNAITSSYSSTR----GISQ 160 Query: 988 -GLSNPVSLTPFQFGVSNLGQEEKK-------EELPKSSSAGFSFGTGVINSTPAPANTI 1039 N S +PF S+ Q ++ EEL SS+ STP A+ Sbjct: 161 LWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSS----------STPLAADRE 210 Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099 E + + ++ P + + K + +P+ +G E +LP Sbjct: 211 SQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRG-------EQLTLPPPPQ-- 261 Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKS-TFSFSMTKP 1158 LG + +T+ L KKA + F + + K + +S S T + +T+P Sbjct: 262 LGYS-------ITAEDLDLEKKASLQW--------FNQALEDKSDAASNSVTETPPITQP 306 Query: 1159 SEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSS 1218 S + PA A A T+ + P+ L + S P G ++T + Sbjct: 307 SFTFT-LPAAAP----ASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAG--AATTEA 359 Query: 1219 SNPPVATFVF-----GQSSNP--VSSSAFGNTAESST-----SQSLLFSQDSKLATTSST 1266 +PP + QS P + S +F + ++ + S++ + D+K T Sbjct: 360 LSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQA 419 Query: 1267 GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQT-P 1325 TA P ++ + F FG TS S+ ++ P+A SA P F T P Sbjct: 420 ETATKPQAT---SAPSPAPKQSFLFGTQNTSPSSPAA------PAASSAPPMFKPIFTAP 470 Query: 1326 TFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPV-------FGQQP 1378 + +G + P P + SS++L PT + PTF V SS PP F +Q Sbjct: 471 PKSEKEGPTPPGPSVTATAPSSSSL-PTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQT 529 Query: 1379 SQSAFGSGTT---------------------PNSSS----AFQFG------SSTTNFNFT 1407 + A TT P++ S AF FG SS + T Sbjct: 530 TTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTST 589 Query: 1408 NNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPA---AFTVGSNGKNVF-------SS 1457 + S F FGA ++ AAS P+ F F + PA TV + +++ SS Sbjct: 590 ATAASQPFLFGAPQAS-AASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLHTAVPTATSS 648 Query: 1458 SGTSFSG 1464 S FSG Sbjct: 649 SAADFSG 655 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 83.2 bits (204), Expect = 2e-15 Identities = 136/666 (20%), Positives = 264/666 (39%), Gaps = 27/666 (4%) Query: 805 SNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQN 864 S+++ DN S S SS + SS + S S S + + S E + Sbjct: 647 SSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSD 706 Query: 865 KADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNF 924 +DS + +S+ + D+S+SS +S +S+S SS SS S + S+ + Sbjct: 707 SSDSDSSDSSDSSNSNSSDS----DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 762 Query: 925 KFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFG 984 D SSDS + S + SS S DS + + Sbjct: 763 NSSDSSD-----SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817 Query: 985 LSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSEN 1044 S S+ S + SN + S + S + NS+ + ++ ++ + Sbjct: 818 SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS 877 Query: 1045 KSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTE 1104 SS + + E+ ++S + + +S++ + + N +S S++ + Sbjct: 878 DSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSS-ESSNSSDNSNSS 936 Query: 1105 EKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESE 1164 + +S S +D+ NS + D NSS S+ S + + S+ Sbjct: 937 DSSNSSDSSDSSDSSNSSDSSNSS-----DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS 991 Query: 1165 QPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVA 1224 + + + +S ++D + N+S SS+S+ ++++ S +S S+ Sbjct: 992 SDSSDS----SDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047 Query: 1225 TFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGAS-SNN 1283 + SSN SS ++++SS S S DS ++ SS + + +S S++ Sbjct: 1048 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSD 1107 Query: 1284 TTTSGFGFGATTTSSSAGSSFVFGTGPSAPS-----ASPAFGANQTPTFGQSQGASQPNP 1338 ++ S ++ +S+S+ SS + S+ S +S + ++ + S +S + Sbjct: 1108 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSD 1167 Query: 1339 PGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFG 1398 S SS ++ S + + + SS S S S+ S ++ +S S+ Sbjct: 1168 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1227 Query: 1399 SSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSS 1458 SS +N +++S S + +NSS + S+ S S ++S + G NG N S S Sbjct: 1228 SSDSN-ESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSG-NGNNNGSDS 1285 Query: 1459 GTSFSG 1464 + G Sbjct: 1286 DSDSEG 1291 Score = 81.6 bits (200), Expect = 5e-15 Identities = 118/601 (19%), Positives = 234/601 (38%), Gaps = 45/601 (7%) Query: 863 QNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTG 922 + K+DS+ + +S+ S D+S S+S+S + SS SS S S + S+ Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD 603 Query: 923 NFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFK 982 SSDS + S+ S D SS+S+ + DSK+D+ Sbjct: 604 --------------SSDSSDSSDSSDSSDSSDSKSD-----SSKSESDSSDSDSKSDSSD 644 Query: 983 FGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTS 1042 S N S SN + SSS+ S + + + +N+ +S Sbjct: 645 SNSSDSSDNSDSSD--SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESS 702 Query: 1043 ENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGR 1102 ++ S + + ++ +S S + + + N +S S S Sbjct: 703 DSSDSSDSDSSDSSDSS-------NSNSSDSDSSNSSDSSDSSNSSDSSDSSDS----SN 751 Query: 1103 TEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKE 1162 + + +S S +D+ + S N ++S S S S + Sbjct: 752 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD 811 Query: 1163 SEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPP 1222 S + + + + +S ++D + +NSS SS + +S G S+ S S+ Sbjct: 812 SSDSSDSDSSNSSDSSNSSDSSDS-------SNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864 Query: 1223 VATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSN 1282 SS+ SS ++++SS S S DS ++ SS + + S+ Sbjct: 865 ------SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS 918 Query: 1283 NTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFG 1342 N++ S ++ S+S+ SS + S+ S++ + +N + + S + + Sbjct: 919 NSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSD 978 Query: 1343 SISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTT 1402 S +SS + + S + + + +SS S ++ S + +SS++ S+ Sbjct: 979 SSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSD 1038 Query: 1403 NFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSF 1462 + + +++S S + +NSS + S+ S S + + + S+ + +SS +S Sbjct: 1039 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSD 1098 Query: 1463 S 1463 S Sbjct: 1099 S 1099 Score = 76.6 bits (187), Expect = 2e-13 Identities = 128/660 (19%), Positives = 254/660 (38%), Gaps = 39/660 (5%) Query: 805 SNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQN 864 SN++ D+ S S + SS++ S S S + + D + Sbjct: 574 SNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDS 633 Query: 865 KADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNF 924 +K + +S + D+S+SS++S +S S SSSSS S + S+ Sbjct: 634 SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD-- 691 Query: 925 KFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFG 984 SSDS + + S+ D SS+S S +D+ Sbjct: 692 ------------SSDSSNSSESSDS-------SDSSDSDSSDSSDSSNSNSSDSDSSNSS 732 Query: 985 LSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSEN 1044 SS SN + ++ + + S S+ S + +S+ + + ++ + Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792 Query: 1045 KSSFNLGTIETKSASVAPFTCKTSEA-KKEEMPATKGGFSFGNVEPASLPSASVFVLGRT 1103 SS + + ++ ++S + + +S++ ++ S + + +S G Sbjct: 793 DSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSD 852 Query: 1104 EEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKES 1163 + +S S +D+ S N ++S S S S + S S Sbjct: 853 SDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS 912 Query: 1164 EQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPV 1223 + + + +++S ++D +NSS SS++ +S SS SS++ Sbjct: 913 DSSDSSNSSDSSESSNSSDN----------SNSSDSSNSSDSSDSSDSSNSSDSSNSSDS 962 Query: 1224 ATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNN 1283 + SN SS N+++SS S S DS ++ SS + + + S+N Sbjct: 963 SNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSS-----DSSDSSN 1017 Query: 1284 TTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGS 1343 ++ S ++ +S S+ SS + S+ S+ + +N + + S +S + S Sbjct: 1018 SSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS-SDSSDSSDSSDSSDSS 1076 Query: 1344 ISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTN 1403 SS ++ S + + + SS S S S+ S + NSS + S+ + Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS-DSSDSSNSSDSSDSSDSSDS 1135 Query: 1404 FNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463 + +N+S S + ++SS + S+ S S + + + S+ + SS +S S Sbjct: 1136 SDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1195 Score = 76.3 bits (186), Expect = 2e-13 Identities = 125/646 (19%), Positives = 244/646 (37%), Gaps = 31/646 (4%) Query: 764 SESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGS 823 S+S+++ +S+SS + + D S S S+N+ D+ S S+ S Sbjct: 687 SDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDS 746 Query: 824 SVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKS 883 S ++SS + S S S + + S N +DS + S+ S Sbjct: 747 SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS------SNSSDSND--SSNSSDSSDSS 798 Query: 884 GFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSI 943 SS SS+S+ SS SS SS S + S+ + D G SDS + Sbjct: 799 NSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNR 858 Query: 944 NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVS 1003 + S S SS+S +S + + S S+ S + S Sbjct: 859 SDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS 918 Query: 1004 NLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPF 1063 N + +S++ S + + + +N+ +S + S N ++S + Sbjct: 919 NSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSD 978 Query: 1064 TCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKAD 1123 + +S++ + S + S S+ + + +S S +D Sbjct: 979 SSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSD 1038 Query: 1124 NEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQ 1183 + + +S + D + S ++ S + S S+ + + +++S ++D Sbjct: 1039 SSDSS--------DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDS 1090 Query: 1184 GAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNT 1243 + ++S SS S+ ++ + S++S S+ + SSN SS + Sbjct: 1091 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSES 1150 Query: 1244 AESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSS 1303 ++SS S S DS ++ SS + S+N++ S ++ +S S+ SS Sbjct: 1151 SDSSDSSDSSDSSDSSDSSDSSDSS-----------DSSNSSDSSDSSDSSDSSDSSDSS 1199 Query: 1304 FVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFG 1363 + S+ S+ + ++ + + S +S N S SS ++ S + + Sbjct: 1200 DSSDSSDSSDSSDSSDSSDSSDS-SDSSDSSDSNESSDSSDSSDSS---DSSNSSDSSDS 1255 Query: 1364 TVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNN 1409 + SS S + SQS G+G S S S +N + +++ Sbjct: 1256 SDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301 Score = 54.7 bits (130), Expect = 7e-07 Identities = 73/332 (21%), Positives = 144/332 (43%), Gaps = 18/332 (5%) Query: 1134 SFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFL 1193 S GN D+N KS + S+ +S + ++ + + S ++D ++ S Sbjct: 526 SNGNGNNGNDDN-DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSD 584 Query: 1194 NNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLL 1253 ++SS SS + ++ + SS SS + + S+ S + + ++SS S S Sbjct: 585 SDSSDSSDSDSSDSS----NSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKS 640 Query: 1254 FSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAP 1313 S DS + +S + ++S+N++ S ++ +SSS+ SS + S+ Sbjct: 641 DSSDSNSSDSSDNSDS------SDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSD 694 Query: 1314 S--ASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQP 1371 S +S + ++ + S + N S SS+++ S + + + SS+S Sbjct: 695 SSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSD 754 Query: 1372 PVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPS 1431 S S+ S ++ +S S+ SS +N + +N+S S + ++SS + S+ S Sbjct: 755 SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSN-DSSNSSDSSDSSNSSDSSNSSDSSDSS 813 Query: 1432 GSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463 S + S + SN + SS +S S Sbjct: 814 DSSDSDSSNS----SDSSNSSDSSDSSNSSDS 841 Score = 51.6 bits (122), Expect = 6e-06 Identities = 70/334 (20%), Positives = 143/334 (42%), Gaps = 16/334 (4%) Query: 1137 NSEQTKDE-NSSKSTFSFSMTKPSEKESEQP-AKATFAFGAQTSTTADQGAAKPVFSFLN 1194 NS+++KD N S S + S ++ + G + +D G K S + Sbjct: 494 NSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSD 553 Query: 1195 NSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLF 1254 +S SS+S+ ++ + S SSS+ + SS+ SS + N+++SS S Sbjct: 554 SSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDS-SNSSDSSDSSDSSD 612 Query: 1255 SQDSKLATTSSTGTAVTPFVFGPG-----ASSNNTTTSGFGFGATTTSSSAGSSFVFGTG 1309 S DS ++ S + ++ + +S +N++ S ++ +S+S+ SS + Sbjct: 613 SSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSS 672 Query: 1310 PSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSS 1369 S+ S+S + +N + + S ++ S SS + + S + + + S+SS Sbjct: 673 DSSDSSSSSDSSNSSDSSDSSDSSN--------SSESSDSSDSSDSDSSDSSDSSNSNSS 724 Query: 1370 QPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQ 1429 S + S + +SS + S+ + + +N+S S + ++SS + S+ Sbjct: 725 DSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 784 Query: 1430 PSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463 + S + + + SN + SS +S S Sbjct: 785 SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDS 818 Score = 39.7 bits (91), Expect = 0.022 Identities = 46/191 (24%), Positives = 84/191 (43%), Gaps = 10/191 (5%) Query: 67 SCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVL 126 S S+D+S+ ++K D + + S+ +D + + SN+ + S S +S+ + Sbjct: 608 SDSSDSSDSSDSSDSKSD----SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN-- 661 Query: 127 TRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSG 186 S + S + S S + S++S+ SS S E DS+ D D+ ++ Sbjct: 662 ---SSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDS 718 Query: 187 FSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNS 246 +S +SD D + S ++S S ++ S S S + +S + N S S S +S Sbjct: 719 SNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS-SNSSDSSDSSDSSNSSDSSDSSDSSDSS 777 Query: 247 SILKTSQLGDS 257 +S DS Sbjct: 778 DSSNSSDSNDS 788 Score = 39.7 bits (91), Expect = 0.022 Identities = 48/191 (25%), Positives = 78/191 (40%), Gaps = 9/191 (4%) Query: 67 SCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVL 126 S S+D+SE +N +SSN +D + + SN+ + S +S +SN D Sbjct: 918 SNSSDSSESSNSSDNSNS------SDSSNSSDSSDSSDS--SNSSDSSNSSDSSNSSDSS 969 Query: 127 TRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSG 186 S S + S S + S+ S+ SS S + DS++ D N S +S Sbjct: 970 DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029 Query: 187 FSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNS 246 SS +SD + + S S ++ S S + +S + + S S S +S Sbjct: 1030 -SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS 1088 Query: 247 SILKTSQLGDS 257 +S DS Sbjct: 1089 DSSNSSDSSDS 1099 Score = 35.4 bits (80), Expect = 0.41 Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 15/200 (7%) Query: 60 NKNEDVCSCSTDTSEVPRWPENKE--DHLVYADEESSNITDGRITPEPAVSNTEEPSTTS 117 + N S S+D+S+ ++ + D +D +SSN +D SN+ + S +S Sbjct: 820 SSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS--------SNSSDSSDSS 871 Query: 118 TASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHD 177 +SN D + S + +S S+ S+ SS S + +S++ D Sbjct: 872 DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931 Query: 178 DDNISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFG 237 + N S +S S + D S N+S S + S S +++ SS + N S Sbjct: 932 NSNSSDSSNSSDSSDSSD---SSNSSDSSNSSDSSNSSDSSDSNSSDSS--DSSNSSDSS 986 Query: 238 TLSPSLGNSSILKTSQLGDS 257 S S +S +S DS Sbjct: 987 DSSDSSDSSDSSDSSNSSDS 1006 Score = 34.7 bits (78), Expect = 0.70 Identities = 46/170 (27%), Positives = 77/170 (45%), Gaps = 10/170 (5%) Query: 89 ADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHC 148 +D +SSN +D + + S++ S +S +S+ D S +RS + S S + Sbjct: 816 SDSDSSNSSDSSNSSDS--SDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873 Query: 149 QPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASDKDITVSKNTSLPPLW 208 S+ S+ S+ S + DS++ D D S+ S SS +SD S N+S Sbjct: 874 SNSSDSSDSSDSNESSNSSDSSDSSNSSDSD--SSDSSNSSDSSD-----SSNSSDSSES 926 Query: 209 SPEAERSHSL-SQHTATSSKKPAFNLSAFGTLSPSLGNSSILKTSQLGDS 257 S ++ S+S S +++ SS + S+ + S NSS S DS Sbjct: 927 SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDS 976 Score = 33.1 bits (74), Expect = 2.0 Identities = 41/188 (21%), Positives = 80/188 (42%), Gaps = 4/188 (2%) Query: 60 NKNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTA 119 + N S S+D+S+ ++ +SSN ++ + + + S++ + S +S Sbjct: 662 SSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSN- 720 Query: 120 SNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDD 179 SN D S + S + S S + S++S+ SS S + DS+ D Sbjct: 721 SNSSD---SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777 Query: 180 NISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTL 239 + S +S + ++ D + S N+S S ++ S S ++ SS + S+ + Sbjct: 778 DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN 837 Query: 240 SPSLGNSS 247 S +SS Sbjct: 838 SSDSSDSS 845 Score = 32.0 bits (71), Expect = 4.5 Identities = 42/190 (22%), Positives = 81/190 (42%), Gaps = 6/190 (3%) Query: 67 SCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPA----VSNTEEPSTTSTASNY 122 S S+D+S+ ++ + +SSN +D + E + S++ + S +S +S+ Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDS 1171 Query: 123 PDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNIS 182 D + S + S + S S + S+ S+ SS S + DS+ D + S Sbjct: 1172 SD--SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229 Query: 183 TTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPS 242 ++ S + D + S N+S S ++ + + + + SK N + + S S Sbjct: 1230 DSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDS 1289 Query: 243 LGNSSILKTS 252 G+ S TS Sbjct: 1290 EGSDSNHSTS 1299 Score = 31.6 bits (70), Expect = 5.9 Identities = 43/199 (21%), Positives = 82/199 (41%), Gaps = 7/199 (3%) Query: 60 NKNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPA-VSNTEEPSTTST 118 + N S S+D+S+ ++ +SS+ +D + + + S++ + S +S Sbjct: 1000 SSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1059 Query: 119 ASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDD 178 +S+ D + S S + S S + S++S+ SS S + DS+ D Sbjct: 1060 SSDSSD--SSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117 Query: 179 DNISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGT 238 + S +S S + D + S N+S S ++ S S + +S + + S Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSS----DSSDSSESSDSSDSSDSSDSSDSSDSSDSSD 1173 Query: 239 LSPSLGNSSILKTSQLGDS 257 S S +S +S DS Sbjct: 1174 SSDSSNSSDSSDSSDSSDS 1192 >gi|56549643 nucleoporin 98kD isoform 3 [Homo sapiens] Length = 937 Score = 78.2 bits (191), Expect = 6e-14 Identities = 135/579 (23%), Positives = 210/579 (36%), Gaps = 124/579 (21%) Query: 900 SSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE-GFKFSKPIGD 958 + SF + G T T N FG G G S+ S N G +KP G Sbjct: 3 NKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGG- 61 Query: 959 FKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQE---EKKEELP 1015 FG SS S+P S + F FG S+G +N + FG ++ G + Sbjct: 62 -LFGTSSFSQPAT----STSTGFGFGTSTGTANTL------FGTASTGTSLFSSQNNAFA 110 Query: 1016 KSSSAGF-SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEE 1074 ++ GF +FGT S+ + G T + + PF Sbjct: 111 QNKPTGFGNFGT-------------------STSSGGLFGTTNTTSNPF----------- 140 Query: 1075 MPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFS 1134 + G FG P+S +A T K P + ++V + N K Q + + Sbjct: 141 --GSTSGSLFG---PSSFTAAPT----GTTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191 Query: 1135 FGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLN 1194 E E + + P + GA T+T Sbjct: 192 MKEYESKSLEELRLEDYQANRKGPQNQ-----------VGAGTTT--------------- 225 Query: 1195 NSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFG-NTAESSTSQSLL 1253 S+PATS+ G+F SST++S F +GQ+ +AFG +T T+ L Sbjct: 226 --GLFGSSPATSSATGLFSSSTTNSG-----FAYGQNK-----TAFGTSTTGFGTNPGGL 273 Query: 1254 FSQDSKLATT-------SSTGTAVTPFVFGPGASSNNTTTSGFG-FGAT----------- 1294 F Q ++ T+ +T T T F FG ++ +T+ G FG T Sbjct: 274 FGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGT 333 Query: 1295 TTSSSAGSSFVFGTGPSAPS-------ASPAFGANQTPTFGQSQGASQPNPPGFGSISSS 1347 T++S G++F GTG + S FG N+ TFG S ++ G + + Sbjct: 334 ATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGN 393 Query: 1348 TALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFT 1407 G+ FG +++S +FG +P+ G+G +A G ++ F Sbjct: 394 KPTLTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASL---FG 450 Query: 1408 NNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446 NN P G + + + GF Q+P A T Sbjct: 451 NNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALT 489 Score = 65.9 bits (159), Expect = 3e-10 Identities = 72/230 (31%), Positives = 102/230 (44%), Gaps = 28/230 (12%) Query: 1225 TFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNT 1284 T +FG S+P +SSA G + S+T+ + Q+ TS+TG P G N Sbjct: 225 TGLFG--SSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPG--GLFGQQNQQ 280 Query: 1285 TTSGFG--FGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFG 1342 TTS F FG TT+ + G SF G ++ P+ N FG +Q + G Sbjct: 281 TTSLFSKPFGQATTTQNTGFSF----GNTSTIGQPS--TNTMGLFGVTQASQPGGLFGTA 334 Query: 1343 SISSSTALFPTGSQPAPPT---FGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGS 1399 + +S+ F TG+ T FG V S+ +FG + FGS TT SA FG Sbjct: 335 TNTSTGTAFGTGTGLFGQTNTGFGAVGST----LFGNN-KLTTFGSSTT----SAPSFG- 384 Query: 1400 STTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGS 1449 TT+ N P+ T G N++T + SG F PA T+G+ Sbjct: 385 -TTSGGLFGNKPT--LTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGT 431 Score = 65.1 bits (157), Expect = 5e-10 Identities = 132/538 (24%), Positives = 195/538 (36%), Gaps = 114/538 (21%) Query: 880 GTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGN-FKFGDQGGFK---IG 935 G G F +S+++ +S K G +S SQ TST F FG G G Sbjct: 34 GGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFG 93 Query: 936 VSSDSGSI-NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVS 994 +S S+ + + F +KP G FG S+ S FG ++ SNP Sbjct: 94 TASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSS------------GGLFGTTNTTSNPFG 141 Query: 995 LTPFQ-FGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTI 1053 T FG S+ P ++ F+ TG A +T ++++++ + Sbjct: 142 STSGSLFGPSSF------TAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEY 195 Query: 1054 ETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTS 1113 E+KS E + E+ A + G P V T P TS Sbjct: 196 ESKSLE---------ELRLEDYQANRKG-----------PQNQVGAGTTTGLFGSSPATS 235 Query: 1114 TSL-VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFA 1172 ++ +F N F++G ++ ST F T P +Q + T Sbjct: 236 SATGLFSSSTTNSG------FAYGQNKTA----FGTSTTGFG-TNPGGLFGQQNQQTTSL 284 Query: 1173 FG---AQTSTTADQGAAKPVFSFLNNSSSSSSTPAT---------SAGGGIFGSSTSSSN 1220 F Q +TT + G FSF N S+ + T S GG+FG++T++S Sbjct: 285 FSKPFGQATTTQNTG-----FSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTST 339 Query: 1221 PPV---ATFVFGQSSN---PVSSSAFGN----TAESSTSQSLLFSQDS------KLATTS 1264 T +FGQ++ V S+ FGN T SST+ + F S K T Sbjct: 340 GTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTL 399 Query: 1265 STGTAVTPFVFGPGASSNNTT-------TSGFGFGATT-TSSSAGSSFVFGT-------- 1308 T T + F FG S N+ T G G GA T+ AG + +FG Sbjct: 400 GTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGP 459 Query: 1309 ---------GPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQP 1357 G + +A+ FGA Q P AS +S P G P Sbjct: 460 LGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSP 517 Score = 58.9 bits (141), Expect = 3e-08 Identities = 93/335 (27%), Positives = 136/335 (40%), Gaps = 52/335 (15%) Query: 1167 AKATFAFGAQTSTTADQGAA--KPVFSFLNNSSSSSSTPATSAGGGI-FGSSTSSSNP-- 1221 A T AFG+ +T G + KP F +SS S PATS G FG+ST ++N Sbjct: 36 AFGTSAFGSSNNTGGLFGNSQTKPGGLF---GTSSFSQPATSTSTGFGFGTSTGTANTLF 92 Query: 1222 ---PVATFVFGQSSNPVSSS---AFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVF 1275 T +F +N + + FGN S++S L + + TTS+ + + +F Sbjct: 93 GTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTN----TTSNPFGSTSGSLF 148 Query: 1276 GPGASSNNTTTSGFGFG---ATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFG-QSQ 1331 GP + + T + F T T AG S T +A + + + Sbjct: 149 GPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDY 208 Query: 1332 GASQPNPPGFGSISSSTALFPTGSQPAPPTF-GTVSSSSQPPVFGQQPSQSAFGS----- 1385 A++ P ++T LF GS PA + G SSS+ F +++AFG+ Sbjct: 209 QANRKGPQNQVGAGTTTGLF--GSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGF 266 Query: 1386 GTTP---------NSSSAFQ--FGSST----TNFNFTNNSPSG---VFTFGANSSTPAAS 1427 GT P ++S F FG +T T F+F N S G T G T A Sbjct: 267 GTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQA-- 324 Query: 1428 AQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSF 1462 +QP G G N S T G +F + T F Sbjct: 325 SQPGGLFGTATNTSTG--TAFGTGTGLFGQTNTGF 357 Score = 51.2 bits (121), Expect = 7e-06 Identities = 80/285 (28%), Positives = 116/285 (40%), Gaps = 49/285 (17%) Query: 1192 FLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS 1251 F S+ +T + GG FG+S FG S+N + FGN S T Sbjct: 17 FGTTSTFGQNTGFGTTSGGAFGTS-----------AFGSSNN--TGGLFGN---SQTKPG 60 Query: 1252 LLF--SQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTG 1309 LF S S+ AT++STG F FG + NT FG +T +S SS Sbjct: 61 GLFGTSSFSQPATSTSTG-----FGFGTSTGTANTL-----FGTASTGTSLFSSQNNAFA 110 Query: 1310 PSAPSASPAFGANQTP--TFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSS 1367 + P+ FG + + FG + S P FGS S S LF S A PT T+ Sbjct: 111 QNKPTGFGNFGTSTSSGGLFGTTNTTSNP----FGSTSGS--LFGPSSFTAAPTGTTIKF 164 Query: 1368 SSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAAS 1427 + PP + + +G + N S+ Q ++ + + + + AN P Sbjct: 165 N--PPT----GTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQ 218 Query: 1428 AQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTS--FSGRKIKTA 1470 + G F SPA S+ +FSSS T+ F+ + KTA Sbjct: 219 VGAGTTTGL-FGSSPAT----SSATGLFSSSTTNSGFAYGQNKTA 258 Score = 47.4 bits (111), Expect = 1e-04 Identities = 51/178 (28%), Positives = 75/178 (42%), Gaps = 38/178 (21%) Query: 1297 SSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPN-----PPGFGSISSSTALF 1351 + S G+ F GTG G T TFGQ+ G + FGS +++ LF Sbjct: 3 NKSFGTPFGGGTG----------GFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLF 52 Query: 1352 PTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTT--------N 1403 FGT SS SQP + + FG GT+ +++ FG+++T N Sbjct: 53 GNSQTKPGGLFGT-SSFSQPAT----STSTGFGFGTSTGTANTL-FGTASTGTSLFSSQN 106 Query: 1404 FNFTNNSPSGVFTFGANSS------TPAASAQPSGS-GGFPFNQSPAAFTVGSNGKNV 1454 F N P+G FG ++S T ++ P GS G F P++FT G + Sbjct: 107 NAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLF--GPSSFTAAPTGTTI 162 Score = 46.6 bits (109), Expect = 2e-04 Identities = 54/186 (29%), Positives = 76/186 (40%), Gaps = 23/186 (12%) Query: 1285 TTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSI 1344 T G G G T+S+ G + FGT + AFG++ G G SQ P G Sbjct: 8 TPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNT--GGLFGNSQTKPGGLFGT 65 Query: 1345 SSSTALFPTGSQPAPPT-----FGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGS 1399 SS SQPA T FGT S+ + +FG ++ G+ + ++AF Sbjct: 66 SSF-------SQPATSTSTGFGFGT-STGTANTLFG----TASTGTSLFSSQNNAFAQNK 113 Query: 1400 STTNFNF-TNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSN---GKNVF 1455 T NF T+ S G+F +S P S S G F +P T+ N G + Sbjct: 114 PTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTM 173 Query: 1456 SSSGTS 1461 +G S Sbjct: 174 VKAGVS 179 Score = 44.3 bits (103), Expect = 9e-04 Identities = 58/231 (25%), Positives = 86/231 (37%), Gaps = 42/231 (18%) Query: 1266 TGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSF--------------------- 1304 TG T FG T+ FG A +S++ G F Sbjct: 14 TGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPAT 73 Query: 1305 ----VFGTGPSAPSASPAFGANQTPT---FGQSQGASQPNPPGFGSISSSTA---LFPTG 1354 FG G S +A+ FG T T Q+ +Q P GFG+ +ST+ LF T Sbjct: 74 STSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTT 133 Query: 1355 SQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTT-----PNSSSAFQFGSSTTNFNFTNN 1409 + + P FG+ S S +FG S +A +GTT P + +TN + + Sbjct: 134 NTTSNP-FGSTSGS----LFGPS-SFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQ 187 Query: 1410 SPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGT 1460 + + + + S + P NQ A T G G + +SS T Sbjct: 188 CITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSAT 238 >gi|239754668 PREDICTED: mucin 12 [Homo sapiens] Length = 1952 Score = 76.6 bits (187), Expect = 2e-13 Identities = 321/1460 (21%), Positives = 515/1460 (35%), Gaps = 224/1460 (15%) Query: 69 STDTSEVPRW-------PENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASN 121 STDT+ P PE+ H +++ + D T ++T S+T + Sbjct: 266 STDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGS--- 322 Query: 122 YPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNI 181 P P+ +H E PS+ P S S +K ST+ H + Sbjct: 323 -PHTTLSPASSTTHEG----EPTTFQSWPSSKDTSPAPSGTTSAF--VKLSTTYHSSPSS 375 Query: 182 STTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSS---KKPAFNLSAFGT 238 + T+ FS AS + S+ S P SP A + +ATS + A++ S T Sbjct: 376 TPTTHFS--ASSTTLGHSEE-STPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGST 432 Query: 239 LSPSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSA 298 + SS + +S + G TT+ ++ + L +T Y + + + Sbjct: 433 QTMHFPESSTT-SGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDS 491 Query: 299 QSYGVTSSTARRILQSLEKMSSPLADAKRIPSI-VSSPLNSPLDRSGIDITDFQAKREKV 357 + S ++ S + M++ + A PS+ V SP+ ++ T K Sbjct: 492 STISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTK- 550 Query: 358 DSQYPPVQRLMTPKPVSIATNRSVYFKPSLTPSG---EFRKTNQRIDNKCSTGYEKNMT- 413 P + T S + + + S+T SG E ++ R + +T + + T Sbjct: 551 ----PGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTM 606 Query: 414 PGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLP 473 PG ++E S S P P LS G + E T F S+P E +P Sbjct: 607 PGLSQESTAS-HSSPG---PTDTTLSPG-STTASSLGPEYTTF-HSRPGSTETTLLPDNT 660 Query: 474 KISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVK 533 S + +S+P + + TT SP+ + Q + + PSS + P Sbjct: 661 TAS-GLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFH-SWPSSNDT------RPAPP 712 Query: 534 STEANVLPPS--SIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPE 591 +T + + PS S G S+P T +S S+T + S+ +H ++ ST P Sbjct: 713 TTTSAFVEPSTTSHGSPSSIP---TTHISARSTTSGLVEESTTYH-SSPGSTQTMHFPES 768 Query: 592 DC-EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGI 650 D G + + I +P S ++ + ++ T SS +S Sbjct: 769 DTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTS--- 825 Query: 651 GFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSA 710 G E A S Q T + + + SP + P + LS Sbjct: 826 GRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSE 885 Query: 711 SGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTV-VSESAET 769 T F + P + P T + A T + VSE + T Sbjct: 886 RSTTF------------------HSSPRS----------PATTLSPASTTSSGVSEESTT 917 Query: 770 MTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSE-----KPGSS 824 S S +T T F D P S + S + D + + +P +S Sbjct: 918 ----SHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTS 973 Query: 825 VPASSSSTVPVSLP-SGGSLGLEK----FKKPEGSWDCELCLVQNKADSTKCLACES-AK 878 P SS ST +LP S + GL + F S D L + + S ++ Sbjct: 974 -PISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSR 1032 Query: 879 PGTK--SGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGV 936 PG+ + F G T S + +S G + ++ P T S+ +G Sbjct: 1033 PGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASS------------LGP 1080 Query: 937 SSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLT 996 S + P S P G+ S P V + + + + T Sbjct: 1081 ESTTFHSGPGSTETTLL-PDNTTASGLLEASTP--VHSSTGSPRTTLSPAGSTTRQGEST 1137 Query: 997 PFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETK 1056 FQ S+ K+ +P + +F S +P++ T + SS G E Sbjct: 1138 TFQSWPSS------KDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEES 1191 Query: 1057 ----SASVAPFTC-----KTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQ 1107 S+ VAP T T+ EE A S G+ + P +S GR+EE + Sbjct: 1192 TTVHSSPVAPATTPSPARSTTSGLVEESTAYHS--SPGSTQTMHFPESST-ASGRSEESR 1248 Query: 1108 QE-----------PVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMT 1156 P T+++LV + + P F S T S +ST S S Sbjct: 1249 TSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGR-SEESTASHSSP 1307 Query: 1157 KPSEKESEQPAKATFAFGAQTSTTADQGAAKPVF-----SFLNNSSSSSSTPATSAGGGI 1211 + P A F TT+ + A F S +S+++TP SA I Sbjct: 1308 ---DTNGITPLPAHF-------TTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTI 1357 Query: 1212 FGSS-------------TSSSNPPVATFVFGQSSN------PVSSSAFGNTAESSTSQSL 1252 SS TSSS T ++ Q+ + P S++ G + ES+T S Sbjct: 1358 LYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSK 1417 Query: 1253 LFSQDSKLA----TTSSTGTAVTPFVFGPGA-----SSNNTTTSGFGFGATTTSSSAGSS 1303 S ++ L+ TTSS T PG+ S +TT G +TT SS GS Sbjct: 1418 PGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGS- 1476 Query: 1304 FVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFG 1363 + + AF + T + Q P+ PGF + T L P T Sbjct: 1477 ----------TETTAFSHSNTMSIHSQQSTPFPDSPGF----THTVL--------PATLT 1514 Query: 1364 TVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSST 1423 T + F S A G+ P S+A T F + + SP+ F A+SST Sbjct: 1515 TTDIGQESTAF--HSSSDATGTTPLPARSTASDLVGEPTTF-YISPSPTYTTLFPASSST 1571 Query: 1424 PAASAQPSGSGGFPFNQSPA 1443 + + + F+ SP+ Sbjct: 1572 SGLTEEST-----TFHTSPS 1586 Score = 71.2 bits (173), Expect = 7e-12 Identities = 302/1441 (20%), Positives = 491/1441 (34%), Gaps = 232/1441 (16%) Query: 78 WPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSH-- 135 +P + + + ++S IT ++ T P +T+TA T S RS Sbjct: 160 FPSHSATSVFVGEPKTSPITSA------SMETTALPGSTTTAGLSEKSTTFYSSPRSPDR 213 Query: 136 -LNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASDK 194 L+ + S + + +TS + P G + DST+ ST S S Sbjct: 214 TLSPARTTSSGVSEKSTTSHSRP----GPTHTIAFPDSTTMPGVSQESTAS--HSIPGST 267 Query: 195 DITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNSSILKTSQL 254 D T+S T+ P PE+ HS +T T+ L + S +L+ S Sbjct: 268 DTTLSPGTTTPSSLGPESTTFHSSPGYTKTTR------------LPDNTTTSGLLEASTP 315 Query: 255 GDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQS 314 S TT A++ + + T +Q+ +K S G TS Sbjct: 316 VHSSTGSPHTTLSPASSTTHEGE--PTTFQS----WPSSKDTSPAPSGTTS--------- 360 Query: 315 LEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVS 374 A K + SSP ++P T E PV TP P Sbjct: 361 --------AFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPAR 412 Query: 375 IATN----------------RSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNR 418 AT+ ++++F S T SG + + ST + K+ TP Sbjct: 413 SATSGHVEESTAYHRSPGSTQTMHFPESSTTSGH---SEESATFHGSTTHTKSSTPSTTA 469 Query: 419 EQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLP 478 + + S + S G R E ++ S P + M VLP S P Sbjct: 470 ALAHTSYHSSLGSTETTHFRDSSTISG----RSEESKASHSSP---DAMATTVLPAGSTP 522 Query: 479 ------ITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIV 532 T S + + + + + S+ P S ++ T SP +T P SS + Sbjct: 523 SVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVS 582 Query: 533 KSTEANVLPPSSIGFTFSVPVAKT-----AELSGSSSTLEPIISSSAHHVTTVNSTNCKK 587 + + + P S T + P + T E + S S+ P ++ + TT +S + Sbjct: 583 EESTTSHSRPGST-HTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEY 641 Query: 588 TP----PEDCEGPFRPAEILKEG------SVLDILKSPGFASPKIDSVAAQPTATSPVVY 637 T P E P G V +SP S Q +T+ + Sbjct: 642 TTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSW 701 Query: 638 -----TRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTA 692 TRPA + +S+ + + S T + T SP T Sbjct: 702 PSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQ 761 Query: 693 KQTGIETPNKSGK---TTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749 E+ SG+ +T S S T I + T + +P + Sbjct: 762 TMHFPESDTTSGRGEESTTSHSST------THTISSAPSTTSALVEEPTSYH------SS 809 Query: 750 PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809 PG+ + + + +S S TGT+ + + E + +S+ + Sbjct: 810 PGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSM 869 Query: 810 DNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869 + + + PG S ST S P + L E ++ ST Sbjct: 870 ETTALPGSTTTPG----LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGST 925 Query: 870 KCLACESAKPGTKSGFKGFDTSSSSSNS--------AASSSFKFG---VSSSSSGPSQTL 918 A + T G T+S SS A++++ G S SSG ++T Sbjct: 926 HTTAFPDST--TTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETT 983 Query: 919 TSTGNFKFGDQGGFKIGVSSDSGSI--NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDS 976 G+ G+S S + +P S S P GVS ES + S Sbjct: 984 ALPGSTT-------TAGLSEKSTTFYSSPRSPDTTLS-PASTTSSGVSEESTTSHSRPGS 1035 Query: 977 KNDNFKFGL--------------SSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGF 1022 + G SS S +L+P S+LG E S F Sbjct: 1036 THTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPE----------STTF 1085 Query: 1023 SFGTGVINSTPAPANTIVTSENKSS----FNLGTIETKSASVAPFTCKTSE--------A 1070 G G +T P NT + ++S + G+ T + S A T + E + Sbjct: 1086 HSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRT-TLSPAGSTTRQGESTTFQSWPS 1144 Query: 1071 KKEEMPA---TKGGF----SFGNVEPASLP----SASVFVLGRTEEK---QQEPV----- 1111 K+ MPA T F + + P+S+P SAS GR+EE PV Sbjct: 1145 SKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATT 1204 Query: 1112 ------TSTSLVFGKKADNEEPKCQPVFSF-------GNSEQTKDENSS--------KST 1150 T++ LV A + P F G SE+++ +SS ST Sbjct: 1205 PSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPST 1264 Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210 S + +P+ S + AT F ++STT+ + +++ + PA G Sbjct: 1265 TSALVEEPTSYHSSPGSIATTHF-PESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSG 1323 Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAF--GNTAESSTSQSLLFSQDSKLATTSSTGT 1268 ST+ P G ++S+A G +A+S+ S S D L+ S T + Sbjct: 1324 RIAESTTFYISP------GSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSS 1377 Query: 1269 AVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFG 1328 +++ + + +T T+ F +TTTS + S F + P + + + G+ T +F Sbjct: 1378 SISGEPTSLYSQAESTHTTAFP-ASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFA 1436 Query: 1329 QSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTT 1388 Q P S S + G TF + S++ F + S +T Sbjct: 1437 QEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQST 1496 Query: 1389 P 1389 P Sbjct: 1497 P 1497 Score = 60.1 bits (144), Expect = 2e-08 Identities = 113/449 (25%), Positives = 167/449 (37%), Gaps = 93/449 (20%) Query: 1017 SSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMP 1076 S+ +GFS TG +T NT S SS T SV T T+ K Sbjct: 77 STFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTA-TKHFLDS 135 Query: 1077 ATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFG 1136 +T G S + S P A+ L + ++TS+ G EPK P+ Sbjct: 136 STNSGHSEESTVSHSGPGATGTTLFPSH-------SATSVFVG------EPKTSPI---- 178 Query: 1137 NSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNS 1196 T S + + P T A ++ STT F S Sbjct: 179 -------------------TSASMETTALPGSTTTAGLSEKSTT---------FYSSPRS 210 Query: 1197 SSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQ 1256 + +PA + G+ ST+S + P T + P S++ G + ES+ S S+ S Sbjct: 211 PDRTLSPARTTSSGVSEKSTTSHSRPGPTHTI---AFPDSTTMPGVSQESTASHSIPGST 267 Query: 1257 DSKLA----TTSSTGTAVTPFVFGPGASS-----NNTTTSGFGFGATTTSSSAGSSF--- 1304 D+ L+ T SS G T F PG + +NTTTSG +T SS GS Sbjct: 268 DTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTL 327 Query: 1305 -------------VFGTGPSAPSASPAFGANQTPTFGQSQGA--SQPNPPGFGSISSSTA 1349 F + PS+ SPA + T F + S P+ S+S+ Sbjct: 328 SPASSTTHEGEPTTFQSWPSSKDTSPA-PSGTTSAFVKLSTTYHSSPSSTPTTHFSASST 386 Query: 1350 LFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNN 1409 + P V++++ PP P++SA SG S++ + ST +F + Sbjct: 387 TLGHSEESTPVHSSPVATATTPP-----PARSA-TSGHVEESTAYHRSPGSTQTMHFPES 440 Query: 1410 S-------PSGVF---TFGANSSTPAASA 1428 S S F T SSTP+ +A Sbjct: 441 STTSGHSEESATFHGSTTHTKSSTPSTTA 469 Score = 59.3 bits (142), Expect = 3e-08 Identities = 224/1061 (21%), Positives = 370/1061 (34%), Gaps = 156/1061 (14%) Query: 459 SKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTS-- 516 + P+ ME LP + S T +SSP + SP ++ + ++ TS Sbjct: 175 TSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHS 234 Query: 517 ----------PSSTGSPMFKFSSP----IVKSTEANVLP----PSSIG-----FTFSVPV 553 P ST P S I ST+ + P PSS+G F S Sbjct: 235 RPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGY 294 Query: 554 AKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPAEILKEGSVLDILK 613 KT L +++T + +S+ H +T S + +P P S D Sbjct: 295 TKTTRLPDNTTTSGLLEASTPVHSST-GSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSP 353 Query: 614 SPG---FASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQ 670 +P A K+ + +++P + S SS+ +G E S T Sbjct: 354 APSGTTSAFVKLSTTYHSSPSSTPTTHF-----SASSTTLGHSEESTPVHSSPVATATTP 408 Query: 671 ---NKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWD 727 T A SP T E+ SG + SA+ G K + Sbjct: 409 PPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTK---SSTP 465 Query: 728 CDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVT------T 781 T + + + ET T + + T++ SE ++ +S + T T Sbjct: 466 STTAALAHTSYHSSLGSTET----THFRDSSTISGRSEESKASHSSPDAMATTVLPAGST 521 Query: 782 GTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGS--SVPASSSST-VPVSLP 838 ++ GD PI S + + +SEK + S P S +T +P S+ Sbjct: 522 PSVLVGDSTPSPISSGSMETTALPGSTTKPG----LSEKSTTFYSSPRSPDTTHLPASMT 577 Query: 839 SGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTK--SGFKGFDTSSSSSN 896 S G +ST ++PG+ + F G T S Sbjct: 578 SSGV----------------------SEESTT----SHSRPGSTHTTAFPGSTTMPGLSQ 611 Query: 897 SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956 + +S SS GP+ T S G+ G S GS P Sbjct: 612 ESTASH-------SSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTL------LPD 658 Query: 957 GDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPK 1016 G+ S P V +++ + + + T F S+ + + P Sbjct: 659 NTTASGLLEASMP--VHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSS---NDTRPAPPT 713 Query: 1017 SSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMP 1076 ++SA T S +P++ T + S G +E + T +S + M Sbjct: 714 TTSAFVEPST---TSHGSPSSIPTTHISARSTTSGLVEEST------TYHSSPGSTQTMH 764 Query: 1077 ATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSF- 1135 + + G E ++ +S T P T+++LV + + P F Sbjct: 765 FPESDTTSGRGEESTTSHSST-----THTISSAPSTTSALVEEPTSYHSSPGSTATTHFP 819 Query: 1136 ------GNSEQTKDENSS-----------KSTFSFSMTKPSEKESEQPAKATFAFGAQTS 1178 G SE++ +SS +ST S + + + + T A T Sbjct: 820 DSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGST- 878 Query: 1179 TTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSS 1238 TT F S +++ +PA++ G+ ST+S + P +T ++ P S++ Sbjct: 879 TTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHT---TAFPDSTT 935 Query: 1239 AFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSS 1298 G + S+TS S S D+ L S+T V P SS +T T+ G+TTT+ Sbjct: 936 TPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSP-ISSGSTETTALP-GSTTTAG 993 Query: 1299 SAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFP-TGSQP 1357 + S F + P +P + + A+ T + + + + PG S+ T FP + + P Sbjct: 994 LSEKSTTFYSSPRSPDTTLS-PASTTSSGVSEESTTSHSRPG----STHTTAFPGSTTMP 1048 Query: 1358 APPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQF-GSSTTNFNFTNNSPSGVFT 1416 T S SS +S S P S++ GS+ T N + SG+ Sbjct: 1049 GVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLL- 1107 Query: 1417 FGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457 +STP S+ +G SPA T F S Sbjct: 1108 ---EASTPVHSS----TGSPRTTLSPAGSTTRQGESTTFQS 1141 Score = 58.5 bits (140), Expect = 5e-08 Identities = 133/623 (21%), Positives = 234/623 (37%), Gaps = 61/623 (9%) Query: 877 AKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGV 936 A GT S F T+ SS S+ ++ F SS++ G S+ T + Sbjct: 354 APSGTTSAFVKLSTTYHSSPSSTPTTH-FSASSTTLGHSEESTPVHSSPVATATTPPPAR 412 Query: 937 SSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLT 996 S+ SG + + + F SS + + + + + SS S +L Sbjct: 413 SATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALA 472 Query: 997 PFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTP-APANTIVTSENKSSFNLGTIET 1055 + S+LG E S+ +G S + +S+P A A T++ + + S +G Sbjct: 473 HTSYH-SSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVG---- 527 Query: 1056 KSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS 1115 ++ +P + + E TK G S + S P R+ + P + TS Sbjct: 528 -DSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSP--------RSPDTTHLPASMTS 578 Query: 1116 LVFGKKA--DNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAF 1173 +++ + P +F S T S +ST S S P++ + + Sbjct: 579 SGVSEESTTSHSRPGSTHTTAFPGST-TMPGLSQESTASHSSPGPTDTTLSPGSTTASSL 637 Query: 1174 GAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSN 1233 G + +T + + +N+++S A+ S ++ +P +T G+S+ Sbjct: 638 GPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTT 697 Query: 1234 --------------PVSSSAF--GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGP 1277 P ++SAF +T + S+ + S +TTS T + P Sbjct: 698 FHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSP 757 Query: 1278 GASSN-----NTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSA----------SPAFGAN 1322 G++ + TTSG G +TT+ SS ++ + PS SA SP G+ Sbjct: 758 GSTQTMHFPESDTTSGRGEESTTSHSS--TTHTISSAPSTTSALVEEPTSYHSSP--GST 813 Query: 1323 QTPTFGQSQGASQPNPPGFGSISSSTALFPTGS--QPAPPTFGTV--SSSSQPPVFGQQP 1378 T F S S + S SS A TG+ PA T + S++ P G Sbjct: 814 ATTHFPDSSTTSGRSEESIASHSSQDA---TGTIVLPARSTNSVLLGESTTSPISSGSME 870 Query: 1379 SQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPF 1438 + + GS TTP S S+ T SP+ + G + + + ++P + F Sbjct: 871 TTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAF 930 Query: 1439 NQSPAAFTVGSNGKNVFSSSGTS 1461 S + + SS G++ Sbjct: 931 PDSTTTPGLSRHSTTSHSSPGST 953 Score = 47.0 bits (110), Expect = 1e-04 Identities = 78/288 (27%), Positives = 124/288 (43%), Gaps = 42/288 (14%) Query: 1191 SFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFV-FGQSSNPVS-SSAFGNTAESST 1248 +F S + ST TS GG +ST SS+ P TF +G S ++ S+A + +SST Sbjct: 78 TFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSST 137 Query: 1249 SQSLLFSQDSKLATT--SSTGTAVTP-------FVFGPGAS---SNNTTTSGFGFGATTT 1296 + S++S ++ + +TGT + P FV P S S + T+ G+TTT Sbjct: 138 NSG--HSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALP-GSTTT 194 Query: 1297 SSSAGSSFVFGTGPSAP--SASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTG 1354 + + S F + P +P + SPA + + + S+P P + T FP Sbjct: 195 AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGP-------THTIAFPDS 247 Query: 1355 SQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNS----SSAFQFGSSTTNFNFTNNS 1410 + + + +S S P G + + G+ TTP+S S+ F S+ + T Sbjct: 248 TTMPGVSQESTASHSIP---GSTDTTLSPGT-TTPSSLGPESTTFH---SSPGYTKTTRL 300 Query: 1411 PSGVFTFG-ANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457 P T G +STP S+ +G SPA+ T F S Sbjct: 301 PDNTTTSGLLEASTPVHSS----TGSPHTTLSPASSTTHEGEPTTFQS 344 >gi|24497609 nucleoporin 62kDa [Homo sapiens] Length = 522 Score = 74.7 bits (182), Expect = 6e-13 Identities = 83/278 (29%), Positives = 119/278 (42%), Gaps = 37/278 (13%) Query: 1197 SSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQS----SNPVSSSAFGNTAESSTSQSL 1252 S ++ TPAT G FG++T +S + G S SN ++ A N + S Sbjct: 61 SLATQTPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSN 120 Query: 1253 LFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTG--- 1309 L + S TSS GTA T FVFGP +S T+ GF T S++ S F G+ Sbjct: 121 LTNAISS-TVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNS 179 Query: 1310 --PSAPSASPAFGANQTPTFGQSQGASQPNPP--------GFGSISSSTALFPTGSQPAP 1359 P+AP+ P A T + GA+QP P S+ +S A PT S Sbjct: 180 AQPTAPATLPFTPATPAAT---TAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTG 236 Query: 1360 PTFGTVSSSSQPPVFGQQ------PSQSAFGSGTTPNSSSA---FQFGSSTTNF--NFTN 1408 + T +++ P G Q P ++ S TT +++A SSTT F N Sbjct: 237 LSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKP 296 Query: 1409 NSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446 +P+G+ S+T AA P G G + +A T Sbjct: 297 LAPAGI-----PSNTAAAVTAPPGPGAAAGAAASSAMT 329 Score = 58.5 bits (140), Expect = 5e-08 Identities = 78/289 (26%), Positives = 117/289 (40%), Gaps = 52/289 (17%) Query: 1208 GGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTG 1267 GG FG++ +++ P F F S + +ST + LFS ++ T +TG Sbjct: 14 GGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTG 73 Query: 1268 ---------TAVTPFVFGPGAS----SNNTTT------SGFGFGAT--------TTSSSA 1300 + T F G GAS SN T SGFG G++ T +SS Sbjct: 74 FTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQ 133 Query: 1301 GSS---FVFGTGPSAPSASPAFGANQTPTFGQS-QGASQPNPPGFGSISSSTALFPTGSQ 1356 G++ FVFG PS S +PA T + G S G S P GF S+ + PT Sbjct: 134 GTAPTGFVFG--PSTTSVAPA-----TTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPA 186 Query: 1357 PAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFT 1416 P T T ++++ P+ +A + T P+ F S T +P+ T Sbjct: 187 TLPFTPATPAATTAGATQPAAPTPTATITSTGPS-----LFASIAT-------APTSSAT 234 Query: 1417 FGANSSTP--AASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463 G + TP A A +G+ GF AA + +++ T+ S Sbjct: 235 TGLSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTS 283 Score = 55.8 bits (133), Expect = 3e-07 Identities = 64/206 (31%), Positives = 83/206 (40%), Gaps = 34/206 (16%) Query: 1266 TGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSF--VFGTGPSAPSASPAFGANQ 1323 TG F FG ++ T +GF F +TS + G +F F S PS A Q Sbjct: 9 TGAPTGGFTFGTAKTATTTPATGFSF---STSGTGGFNFGAPFQPATSTPSTGLFSLATQ 65 Query: 1324 TP-------TFGQSQGASQPNPPGFGSISSSTALFPTGSQPA---PPTFGTVSSSSQPPV 1373 TP TFG + AS G +S L T + PA P FG SS+ + Sbjct: 66 TPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAI 125 Query: 1374 FGQQPSQSAFGSGTTPNSSSAFQFGSSTTN---------FNFTNNSPSGVFTFGANSSTP 1424 S GT P + F FG STT+ F+FT S + G N + Sbjct: 126 ----SSTVTSSQGTAP---TGFVFGPSTTSVAPATTSGGFSFTGGSTAQ--PSGFNIGSA 176 Query: 1425 AASAQPSGSGGFPFN-QSPAAFTVGS 1449 SAQP+ PF +PAA T G+ Sbjct: 177 GNSAQPTAPATLPFTPATPAATTAGA 202 Score = 47.8 bits (112), Expect = 8e-05 Identities = 51/188 (27%), Positives = 76/188 (40%), Gaps = 37/188 (19%) Query: 1287 SGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISS 1346 SGF FG T + F FGT +A + TP G S S FG+ Sbjct: 2 SGFNFGGT---GAPTGGFTFGTAKTATT---------TPATGFSFSTSGTGGFNFGA--- 46 Query: 1347 STALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNF 1406 P + P+ G S ++Q P Q + FG+ T + + F G + N Sbjct: 47 -----PFQPATSTPSTGLFSLATQTP--ATQTTGFTFGTATLASGGTGFSLGIGASKLNL 99 Query: 1407 TNN-------SPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNV---FS 1456 +N +PSG F G+++ T A S+ + S G +P F G + +V + Sbjct: 100 SNTAATPAMANPSG-FGLGSSNLTNAISSTVTSSQG----TAPTGFVFGPSTTSVAPATT 154 Query: 1457 SSGTSFSG 1464 S G SF+G Sbjct: 155 SGGFSFTG 162 Score = 45.8 bits (107), Expect = 3e-04 Identities = 86/378 (22%), Positives = 129/378 (34%), Gaps = 85/378 (22%) Query: 949 GFKFS---KPIGDFKFGVSSESKPEEVK----KDSKNDNFKFGL---------SSGLSNP 992 GF F P G F FG + + S F FG S+GL + Sbjct: 3 GFNFGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSL 62 Query: 993 VSLTP------FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKS 1046 + TP F FG + L S GFS G G + N S Sbjct: 63 ATQTPATQTTGFTFGTATLA----------SGGTGFSLGIGASKLNLSNTAATPAMANPS 112 Query: 1047 SFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFG----NVEPASLPSASVFVLGR 1102 F LG+ +A + T A GF FG +V PA+ F G Sbjct: 113 GFGLGSSNLTNAISSTVTSSQGTAPT--------GFVFGPSTTSVAPATTSGGFSFTGGS 164 Query: 1103 TEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKE 1162 T + P + S GNS Q ++ +T F+ P+ Sbjct: 165 TAQ---------------------PSGFNIGSAGNSAQP----TAPATLPFTPATPAATT 199 Query: 1163 S--EQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSST-------PATSAGGGIFG 1213 + QPA T T+T G + +F+ + + +SS+T P T+AG G Sbjct: 200 AGATQPAAPT-----PTATITSTGPS--LFASIATAPTSSATTGLSLCTPVTTAGAPTAG 252 Query: 1214 SSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPF 1273 + S P A +++ +++ T+ SST+ L + A S A Sbjct: 253 TQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKPLAPAGIPSNTAAAVTA 312 Query: 1274 VFGPGASSNNTTTSGFGF 1291 GPGA++ +S + Sbjct: 313 PPGPGAAAGAAASSAMTY 330 Score = 42.7 bits (99), Expect = 0.003 Identities = 74/345 (21%), Positives = 131/345 (37%), Gaps = 69/345 (20%) Query: 878 KPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS 937 +P T + G + ++ + + ++ F FG ++ +SG + GF +G+ Sbjct: 49 QPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGT---------------GFSLGIG 93 Query: 938 SDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTP 997 + +++ + + P G FG+ S N +SS +++ P Sbjct: 94 ASKLNLSNTAATPAMANPSG---FGLGS-------------SNLTNAISSTVTSSQGTAP 137 Query: 998 --FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIET 1055 F FG S P ++S GFSF G ST P S FN+G+ Sbjct: 138 TGFVFGPST------TSVAPATTSGGFSFTGG---STAQP----------SGFNIGSAGN 178 Query: 1056 KSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPAS-LPSASVFVLGRTEEKQQEPVTST 1114 + AP T + PAT + G +PA+ P+A++ G + ++ Sbjct: 179 SAQPTAPATLPFT-------PATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTS 231 Query: 1115 SLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFG 1174 S G C PV + G S K+ + S T + + A AT Sbjct: 232 SATTGLSL------CTPVTTAGAPTAGTQGFSLKAPGAASGTSTT---TSTAATATATTT 282 Query: 1175 AQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSS 1219 + +STT KP+ S+++++ A G G++ SS+ Sbjct: 283 SSSSTTGFALNLKPLAPAGIPSNTAAAVTAPPGPGAAAGAAASSA 327 Score = 31.2 bits (69), Expect = 7.7 Identities = 66/299 (22%), Positives = 107/299 (35%), Gaps = 33/299 (11%) Query: 369 TPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYP 428 T K + F S T F Q + STG T Q + +GF++ Sbjct: 20 TAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLAT--QTPATQTTGFTFG 77 Query: 429 NFSLPAAN-GLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSS--SLP 485 +L + G S G+G + + P + IS +TSS + P Sbjct: 78 TATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQGTAP 137 Query: 486 TFNFSSPEITTSSPSPINS-------SQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEAN 538 T P T+ +P+ + S A + + S ++ P + P +T A Sbjct: 138 TGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPA- 196 Query: 539 VLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598 ++ G T TA ++ + +L I+++ T + C TP P Sbjct: 197 ---ATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLC--TPVTTAGAP-- 249 Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLK 657 G+ LK+PG AS + + TAT A ++ SSS GF +LK Sbjct: 250 -----TAGTQGFSLKAPGAASGTSTTTSTAATAT--------ATTTSSSSTTGFALNLK 295 >gi|24497607 nucleoporin 62kDa [Homo sapiens] Length = 522 Score = 74.7 bits (182), Expect = 6e-13 Identities = 83/278 (29%), Positives = 119/278 (42%), Gaps = 37/278 (13%) Query: 1197 SSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQS----SNPVSSSAFGNTAESSTSQSL 1252 S ++ TPAT G FG++T +S + G S SN ++ A N + S Sbjct: 61 SLATQTPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSN 120 Query: 1253 LFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTG--- 1309 L + S TSS GTA T FVFGP +S T+ GF T S++ S F G+ Sbjct: 121 LTNAISS-TVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNS 179 Query: 1310 --PSAPSASPAFGANQTPTFGQSQGASQPNPP--------GFGSISSSTALFPTGSQPAP 1359 P+AP+ P A T + GA+QP P S+ +S A PT S Sbjct: 180 AQPTAPATLPFTPATPAAT---TAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTG 236 Query: 1360 PTFGTVSSSSQPPVFGQQ------PSQSAFGSGTTPNSSSA---FQFGSSTTNF--NFTN 1408 + T +++ P G Q P ++ S TT +++A SSTT F N Sbjct: 237 LSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKP 296 Query: 1409 NSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446 +P+G+ S+T AA P G G + +A T Sbjct: 297 LAPAGI-----PSNTAAAVTAPPGPGAAAGAAASSAMT 329 Score = 58.5 bits (140), Expect = 5e-08 Identities = 78/289 (26%), Positives = 117/289 (40%), Gaps = 52/289 (17%) Query: 1208 GGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTG 1267 GG FG++ +++ P F F S + +ST + LFS ++ T +TG Sbjct: 14 GGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTG 73 Query: 1268 ---------TAVTPFVFGPGAS----SNNTTT------SGFGFGAT--------TTSSSA 1300 + T F G GAS SN T SGFG G++ T +SS Sbjct: 74 FTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQ 133 Query: 1301 GSS---FVFGTGPSAPSASPAFGANQTPTFGQS-QGASQPNPPGFGSISSSTALFPTGSQ 1356 G++ FVFG PS S +PA T + G S G S P GF S+ + PT Sbjct: 134 GTAPTGFVFG--PSTTSVAPA-----TTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPA 186 Query: 1357 PAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFT 1416 P T T ++++ P+ +A + T P+ F S T +P+ T Sbjct: 187 TLPFTPATPAATTAGATQPAAPTPTATITSTGPS-----LFASIAT-------APTSSAT 234 Query: 1417 FGANSSTP--AASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463 G + TP A A +G+ GF AA + +++ T+ S Sbjct: 235 TGLSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTS 283 Score = 55.8 bits (133), Expect = 3e-07 Identities = 64/206 (31%), Positives = 83/206 (40%), Gaps = 34/206 (16%) Query: 1266 TGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSF--VFGTGPSAPSASPAFGANQ 1323 TG F FG ++ T +GF F +TS + G +F F S PS A Q Sbjct: 9 TGAPTGGFTFGTAKTATTTPATGFSF---STSGTGGFNFGAPFQPATSTPSTGLFSLATQ 65 Query: 1324 TP-------TFGQSQGASQPNPPGFGSISSSTALFPTGSQPA---PPTFGTVSSSSQPPV 1373 TP TFG + AS G +S L T + PA P FG SS+ + Sbjct: 66 TPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAI 125 Query: 1374 FGQQPSQSAFGSGTTPNSSSAFQFGSSTTN---------FNFTNNSPSGVFTFGANSSTP 1424 S GT P + F FG STT+ F+FT S + G N + Sbjct: 126 ----SSTVTSSQGTAP---TGFVFGPSTTSVAPATTSGGFSFTGGSTAQ--PSGFNIGSA 176 Query: 1425 AASAQPSGSGGFPFN-QSPAAFTVGS 1449 SAQP+ PF +PAA T G+ Sbjct: 177 GNSAQPTAPATLPFTPATPAATTAGA 202 Score = 47.8 bits (112), Expect = 8e-05 Identities = 51/188 (27%), Positives = 76/188 (40%), Gaps = 37/188 (19%) Query: 1287 SGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISS 1346 SGF FG T + F FGT +A + TP G S S FG+ Sbjct: 2 SGFNFGGT---GAPTGGFTFGTAKTATT---------TPATGFSFSTSGTGGFNFGA--- 46 Query: 1347 STALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNF 1406 P + P+ G S ++Q P Q + FG+ T + + F G + N Sbjct: 47 -----PFQPATSTPSTGLFSLATQTP--ATQTTGFTFGTATLASGGTGFSLGIGASKLNL 99 Query: 1407 TNN-------SPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNV---FS 1456 +N +PSG F G+++ T A S+ + S G +P F G + +V + Sbjct: 100 SNTAATPAMANPSG-FGLGSSNLTNAISSTVTSSQG----TAPTGFVFGPSTTSVAPATT 154 Query: 1457 SSGTSFSG 1464 S G SF+G Sbjct: 155 SGGFSFTG 162 Score = 45.8 bits (107), Expect = 3e-04 Identities = 86/378 (22%), Positives = 129/378 (34%), Gaps = 85/378 (22%) Query: 949 GFKFS---KPIGDFKFGVSSESKPEEVK----KDSKNDNFKFGL---------SSGLSNP 992 GF F P G F FG + + S F FG S+GL + Sbjct: 3 GFNFGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSL 62 Query: 993 VSLTP------FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKS 1046 + TP F FG + L S GFS G G + N S Sbjct: 63 ATQTPATQTTGFTFGTATLA----------SGGTGFSLGIGASKLNLSNTAATPAMANPS 112 Query: 1047 SFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFG----NVEPASLPSASVFVLGR 1102 F LG+ +A + T A GF FG +V PA+ F G Sbjct: 113 GFGLGSSNLTNAISSTVTSSQGTAPT--------GFVFGPSTTSVAPATTSGGFSFTGGS 164 Query: 1103 TEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKE 1162 T + P + S GNS Q ++ +T F+ P+ Sbjct: 165 TAQ---------------------PSGFNIGSAGNSAQP----TAPATLPFTPATPAATT 199 Query: 1163 S--EQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSST-------PATSAGGGIFG 1213 + QPA T T+T G + +F+ + + +SS+T P T+AG G Sbjct: 200 AGATQPAAPT-----PTATITSTGPS--LFASIATAPTSSATTGLSLCTPVTTAGAPTAG 252 Query: 1214 SSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPF 1273 + S P A +++ +++ T+ SST+ L + A S A Sbjct: 253 TQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKPLAPAGIPSNTAAAVTA 312 Query: 1274 VFGPGASSNNTTTSGFGF 1291 GPGA++ +S + Sbjct: 313 PPGPGAAAGAAASSAMTY 330 Score = 42.7 bits (99), Expect = 0.003 Identities = 74/345 (21%), Positives = 131/345 (37%), Gaps = 69/345 (20%) Query: 878 KPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS 937 +P T + G + ++ + + ++ F FG ++ +SG + GF +G+ Sbjct: 49 QPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGT---------------GFSLGIG 93 Query: 938 SDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTP 997 + +++ + + P G FG+ S N +SS +++ P Sbjct: 94 ASKLNLSNTAATPAMANPSG---FGLGS-------------SNLTNAISSTVTSSQGTAP 137 Query: 998 --FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIET 1055 F FG S P ++S GFSF G ST P S FN+G+ Sbjct: 138 TGFVFGPST------TSVAPATTSGGFSFTGG---STAQP----------SGFNIGSAGN 178 Query: 1056 KSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPAS-LPSASVFVLGRTEEKQQEPVTST 1114 + AP T + PAT + G +PA+ P+A++ G + ++ Sbjct: 179 SAQPTAPATLPFT-------PATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTS 231 Query: 1115 SLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFG 1174 S G C PV + G S K+ + S T + + A AT Sbjct: 232 SATTGLSL------CTPVTTAGAPTAGTQGFSLKAPGAASGTSTT---TSTAATATATTT 282 Query: 1175 AQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSS 1219 + +STT KP+ S+++++ A G G++ SS+ Sbjct: 283 SSSSTTGFALNLKPLAPAGIPSNTAAAVTAPPGPGAAAGAAASSA 327 Score = 31.2 bits (69), Expect = 7.7 Identities = 66/299 (22%), Positives = 107/299 (35%), Gaps = 33/299 (11%) Query: 369 TPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYP 428 T K + F S T F Q + STG T Q + +GF++ Sbjct: 20 TAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLAT--QTPATQTTGFTFG 77 Query: 429 NFSLPAAN-GLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSS--SLP 485 +L + G S G+G + + P + IS +TSS + P Sbjct: 78 TATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQGTAP 137 Query: 486 TFNFSSPEITTSSPSPINS-------SQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEAN 538 T P T+ +P+ + S A + + S ++ P + P +T A Sbjct: 138 TGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPA- 196 Query: 539 VLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598 ++ G T TA ++ + +L I+++ T + C TP P Sbjct: 197 ---ATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLC--TPVTTAGAP-- 249 Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLK 657 G+ LK+PG AS + + TAT A ++ SSS GF +LK Sbjct: 250 -----TAGTQGFSLKAPGAASGTSTTTSTAATAT--------ATTTSSSSTTGFALNLK 295 >gi|24497605 nucleoporin 62kDa [Homo sapiens] Length = 522 Score = 74.7 bits (182), Expect = 6e-13 Identities = 83/278 (29%), Positives = 119/278 (42%), Gaps = 37/278 (13%) Query: 1197 SSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQS----SNPVSSSAFGNTAESSTSQSL 1252 S ++ TPAT G FG++T +S + G S SN ++ A N + S Sbjct: 61 SLATQTPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSN 120 Query: 1253 LFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTG--- 1309 L + S TSS GTA T FVFGP +S T+ GF T S++ S F G+ Sbjct: 121 LTNAISS-TVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNS 179 Query: 1310 --PSAPSASPAFGANQTPTFGQSQGASQPNPP--------GFGSISSSTALFPTGSQPAP 1359 P+AP+ P A T + GA+QP P S+ +S A PT S Sbjct: 180 AQPTAPATLPFTPATPAAT---TAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTG 236 Query: 1360 PTFGTVSSSSQPPVFGQQ------PSQSAFGSGTTPNSSSA---FQFGSSTTNF--NFTN 1408 + T +++ P G Q P ++ S TT +++A SSTT F N Sbjct: 237 LSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKP 296 Query: 1409 NSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446 +P+G+ S+T AA P G G + +A T Sbjct: 297 LAPAGI-----PSNTAAAVTAPPGPGAAAGAAASSAMT 329 Score = 58.5 bits (140), Expect = 5e-08 Identities = 78/289 (26%), Positives = 117/289 (40%), Gaps = 52/289 (17%) Query: 1208 GGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTG 1267 GG FG++ +++ P F F S + +ST + LFS ++ T +TG Sbjct: 14 GGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTG 73 Query: 1268 ---------TAVTPFVFGPGAS----SNNTTT------SGFGFGAT--------TTSSSA 1300 + T F G GAS SN T SGFG G++ T +SS Sbjct: 74 FTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQ 133 Query: 1301 GSS---FVFGTGPSAPSASPAFGANQTPTFGQS-QGASQPNPPGFGSISSSTALFPTGSQ 1356 G++ FVFG PS S +PA T + G S G S P GF S+ + PT Sbjct: 134 GTAPTGFVFG--PSTTSVAPA-----TTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPA 186 Query: 1357 PAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFT 1416 P T T ++++ P+ +A + T P+ F S T +P+ T Sbjct: 187 TLPFTPATPAATTAGATQPAAPTPTATITSTGPS-----LFASIAT-------APTSSAT 234 Query: 1417 FGANSSTP--AASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463 G + TP A A +G+ GF AA + +++ T+ S Sbjct: 235 TGLSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTS 283 Score = 55.8 bits (133), Expect = 3e-07 Identities = 64/206 (31%), Positives = 83/206 (40%), Gaps = 34/206 (16%) Query: 1266 TGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSF--VFGTGPSAPSASPAFGANQ 1323 TG F FG ++ T +GF F +TS + G +F F S PS A Q Sbjct: 9 TGAPTGGFTFGTAKTATTTPATGFSF---STSGTGGFNFGAPFQPATSTPSTGLFSLATQ 65 Query: 1324 TP-------TFGQSQGASQPNPPGFGSISSSTALFPTGSQPA---PPTFGTVSSSSQPPV 1373 TP TFG + AS G +S L T + PA P FG SS+ + Sbjct: 66 TPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAI 125 Query: 1374 FGQQPSQSAFGSGTTPNSSSAFQFGSSTTN---------FNFTNNSPSGVFTFGANSSTP 1424 S GT P + F FG STT+ F+FT S + G N + Sbjct: 126 ----SSTVTSSQGTAP---TGFVFGPSTTSVAPATTSGGFSFTGGSTAQ--PSGFNIGSA 176 Query: 1425 AASAQPSGSGGFPFN-QSPAAFTVGS 1449 SAQP+ PF +PAA T G+ Sbjct: 177 GNSAQPTAPATLPFTPATPAATTAGA 202 Score = 47.8 bits (112), Expect = 8e-05 Identities = 51/188 (27%), Positives = 76/188 (40%), Gaps = 37/188 (19%) Query: 1287 SGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISS 1346 SGF FG T + F FGT +A + TP G S S FG+ Sbjct: 2 SGFNFGGT---GAPTGGFTFGTAKTATT---------TPATGFSFSTSGTGGFNFGA--- 46 Query: 1347 STALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNF 1406 P + P+ G S ++Q P Q + FG+ T + + F G + N Sbjct: 47 -----PFQPATSTPSTGLFSLATQTP--ATQTTGFTFGTATLASGGTGFSLGIGASKLNL 99 Query: 1407 TNN-------SPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNV---FS 1456 +N +PSG F G+++ T A S+ + S G +P F G + +V + Sbjct: 100 SNTAATPAMANPSG-FGLGSSNLTNAISSTVTSSQG----TAPTGFVFGPSTTSVAPATT 154 Query: 1457 SSGTSFSG 1464 S G SF+G Sbjct: 155 SGGFSFTG 162 Score = 45.8 bits (107), Expect = 3e-04 Identities = 86/378 (22%), Positives = 129/378 (34%), Gaps = 85/378 (22%) Query: 949 GFKFS---KPIGDFKFGVSSESKPEEVK----KDSKNDNFKFGL---------SSGLSNP 992 GF F P G F FG + + S F FG S+GL + Sbjct: 3 GFNFGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSL 62 Query: 993 VSLTP------FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKS 1046 + TP F FG + L S GFS G G + N S Sbjct: 63 ATQTPATQTTGFTFGTATLA----------SGGTGFSLGIGASKLNLSNTAATPAMANPS 112 Query: 1047 SFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFG----NVEPASLPSASVFVLGR 1102 F LG+ +A + T A GF FG +V PA+ F G Sbjct: 113 GFGLGSSNLTNAISSTVTSSQGTAPT--------GFVFGPSTTSVAPATTSGGFSFTGGS 164 Query: 1103 TEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKE 1162 T + P + S GNS Q ++ +T F+ P+ Sbjct: 165 TAQ---------------------PSGFNIGSAGNSAQP----TAPATLPFTPATPAATT 199 Query: 1163 S--EQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSST-------PATSAGGGIFG 1213 + QPA T T+T G + +F+ + + +SS+T P T+AG G Sbjct: 200 AGATQPAAPT-----PTATITSTGPS--LFASIATAPTSSATTGLSLCTPVTTAGAPTAG 252 Query: 1214 SSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPF 1273 + S P A +++ +++ T+ SST+ L + A S A Sbjct: 253 TQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKPLAPAGIPSNTAAAVTA 312 Query: 1274 VFGPGASSNNTTTSGFGF 1291 GPGA++ +S + Sbjct: 313 PPGPGAAAGAAASSAMTY 330 Score = 42.7 bits (99), Expect = 0.003 Identities = 74/345 (21%), Positives = 131/345 (37%), Gaps = 69/345 (20%) Query: 878 KPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS 937 +P T + G + ++ + + ++ F FG ++ +SG + GF +G+ Sbjct: 49 QPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGT---------------GFSLGIG 93 Query: 938 SDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTP 997 + +++ + + P G FG+ S N +SS +++ P Sbjct: 94 ASKLNLSNTAATPAMANPSG---FGLGS-------------SNLTNAISSTVTSSQGTAP 137 Query: 998 --FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIET 1055 F FG S P ++S GFSF G ST P S FN+G+ Sbjct: 138 TGFVFGPST------TSVAPATTSGGFSFTGG---STAQP----------SGFNIGSAGN 178 Query: 1056 KSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPAS-LPSASVFVLGRTEEKQQEPVTST 1114 + AP T + PAT + G +PA+ P+A++ G + ++ Sbjct: 179 SAQPTAPATLPFT-------PATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTS 231 Query: 1115 SLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFG 1174 S G C PV + G S K+ + S T + + A AT Sbjct: 232 SATTGLSL------CTPVTTAGAPTAGTQGFSLKAPGAASGTSTT---TSTAATATATTT 282 Query: 1175 AQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSS 1219 + +STT KP+ S+++++ A G G++ SS+ Sbjct: 283 SSSSTTGFALNLKPLAPAGIPSNTAAAVTAPPGPGAAAGAAASSA 327 Score = 31.2 bits (69), Expect = 7.7 Identities = 66/299 (22%), Positives = 107/299 (35%), Gaps = 33/299 (11%) Query: 369 TPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYP 428 T K + F S T F Q + STG T Q + +GF++ Sbjct: 20 TAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLAT--QTPATQTTGFTFG 77 Query: 429 NFSLPAAN-GLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSS--SLP 485 +L + G S G+G + + P + IS +TSS + P Sbjct: 78 TATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQGTAP 137 Query: 486 TFNFSSPEITTSSPSPINS-------SQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEAN 538 T P T+ +P+ + S A + + S ++ P + P +T A Sbjct: 138 TGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPA- 196 Query: 539 VLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598 ++ G T TA ++ + +L I+++ T + C TP P Sbjct: 197 ---ATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLC--TPVTTAGAP-- 249 Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLK 657 G+ LK+PG AS + + TAT A ++ SSS GF +LK Sbjct: 250 -----TAGTQGFSLKAPGAASGTSTTTSTAATAT--------ATTTSSSSTTGFALNLK 295 >gi|24497603 nucleoporin 62kDa [Homo sapiens] Length = 522 Score = 74.7 bits (182), Expect = 6e-13 Identities = 83/278 (29%), Positives = 119/278 (42%), Gaps = 37/278 (13%) Query: 1197 SSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQS----SNPVSSSAFGNTAESSTSQSL 1252 S ++ TPAT G FG++T +S + G S SN ++ A N + S Sbjct: 61 SLATQTPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSN 120 Query: 1253 LFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTG--- 1309 L + S TSS GTA T FVFGP +S T+ GF T S++ S F G+ Sbjct: 121 LTNAISS-TVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNS 179 Query: 1310 --PSAPSASPAFGANQTPTFGQSQGASQPNPP--------GFGSISSSTALFPTGSQPAP 1359 P+AP+ P A T + GA+QP P S+ +S A PT S Sbjct: 180 AQPTAPATLPFTPATPAAT---TAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTG 236 Query: 1360 PTFGTVSSSSQPPVFGQQ------PSQSAFGSGTTPNSSSA---FQFGSSTTNF--NFTN 1408 + T +++ P G Q P ++ S TT +++A SSTT F N Sbjct: 237 LSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKP 296 Query: 1409 NSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446 +P+G+ S+T AA P G G + +A T Sbjct: 297 LAPAGI-----PSNTAAAVTAPPGPGAAAGAAASSAMT 329 Score = 58.5 bits (140), Expect = 5e-08 Identities = 78/289 (26%), Positives = 117/289 (40%), Gaps = 52/289 (17%) Query: 1208 GGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTG 1267 GG FG++ +++ P F F S + +ST + LFS ++ T +TG Sbjct: 14 GGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTG 73 Query: 1268 ---------TAVTPFVFGPGAS----SNNTTT------SGFGFGAT--------TTSSSA 1300 + T F G GAS SN T SGFG G++ T +SS Sbjct: 74 FTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQ 133 Query: 1301 GSS---FVFGTGPSAPSASPAFGANQTPTFGQS-QGASQPNPPGFGSISSSTALFPTGSQ 1356 G++ FVFG PS S +PA T + G S G S P GF S+ + PT Sbjct: 134 GTAPTGFVFG--PSTTSVAPA-----TTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPA 186 Query: 1357 PAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFT 1416 P T T ++++ P+ +A + T P+ F S T +P+ T Sbjct: 187 TLPFTPATPAATTAGATQPAAPTPTATITSTGPS-----LFASIAT-------APTSSAT 234 Query: 1417 FGANSSTP--AASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463 G + TP A A +G+ GF AA + +++ T+ S Sbjct: 235 TGLSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTS 283 Score = 55.8 bits (133), Expect = 3e-07 Identities = 64/206 (31%), Positives = 83/206 (40%), Gaps = 34/206 (16%) Query: 1266 TGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSF--VFGTGPSAPSASPAFGANQ 1323 TG F FG ++ T +GF F +TS + G +F F S PS A Q Sbjct: 9 TGAPTGGFTFGTAKTATTTPATGFSF---STSGTGGFNFGAPFQPATSTPSTGLFSLATQ 65 Query: 1324 TP-------TFGQSQGASQPNPPGFGSISSSTALFPTGSQPA---PPTFGTVSSSSQPPV 1373 TP TFG + AS G +S L T + PA P FG SS+ + Sbjct: 66 TPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAI 125 Query: 1374 FGQQPSQSAFGSGTTPNSSSAFQFGSSTTN---------FNFTNNSPSGVFTFGANSSTP 1424 S GT P + F FG STT+ F+FT S + G N + Sbjct: 126 ----SSTVTSSQGTAP---TGFVFGPSTTSVAPATTSGGFSFTGGSTAQ--PSGFNIGSA 176 Query: 1425 AASAQPSGSGGFPFN-QSPAAFTVGS 1449 SAQP+ PF +PAA T G+ Sbjct: 177 GNSAQPTAPATLPFTPATPAATTAGA 202 Score = 47.8 bits (112), Expect = 8e-05 Identities = 51/188 (27%), Positives = 76/188 (40%), Gaps = 37/188 (19%) Query: 1287 SGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISS 1346 SGF FG T + F FGT +A + TP G S S FG+ Sbjct: 2 SGFNFGGT---GAPTGGFTFGTAKTATT---------TPATGFSFSTSGTGGFNFGA--- 46 Query: 1347 STALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNF 1406 P + P+ G S ++Q P Q + FG+ T + + F G + N Sbjct: 47 -----PFQPATSTPSTGLFSLATQTP--ATQTTGFTFGTATLASGGTGFSLGIGASKLNL 99 Query: 1407 TNN-------SPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNV---FS 1456 +N +PSG F G+++ T A S+ + S G +P F G + +V + Sbjct: 100 SNTAATPAMANPSG-FGLGSSNLTNAISSTVTSSQG----TAPTGFVFGPSTTSVAPATT 154 Query: 1457 SSGTSFSG 1464 S G SF+G Sbjct: 155 SGGFSFTG 162 Score = 45.8 bits (107), Expect = 3e-04 Identities = 86/378 (22%), Positives = 129/378 (34%), Gaps = 85/378 (22%) Query: 949 GFKFS---KPIGDFKFGVSSESKPEEVK----KDSKNDNFKFGL---------SSGLSNP 992 GF F P G F FG + + S F FG S+GL + Sbjct: 3 GFNFGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSL 62 Query: 993 VSLTP------FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKS 1046 + TP F FG + L S GFS G G + N S Sbjct: 63 ATQTPATQTTGFTFGTATLA----------SGGTGFSLGIGASKLNLSNTAATPAMANPS 112 Query: 1047 SFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFG----NVEPASLPSASVFVLGR 1102 F LG+ +A + T A GF FG +V PA+ F G Sbjct: 113 GFGLGSSNLTNAISSTVTSSQGTAPT--------GFVFGPSTTSVAPATTSGGFSFTGGS 164 Query: 1103 TEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKE 1162 T + P + S GNS Q ++ +T F+ P+ Sbjct: 165 TAQ---------------------PSGFNIGSAGNSAQP----TAPATLPFTPATPAATT 199 Query: 1163 S--EQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSST-------PATSAGGGIFG 1213 + QPA T T+T G + +F+ + + +SS+T P T+AG G Sbjct: 200 AGATQPAAPT-----PTATITSTGPS--LFASIATAPTSSATTGLSLCTPVTTAGAPTAG 252 Query: 1214 SSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPF 1273 + S P A +++ +++ T+ SST+ L + A S A Sbjct: 253 TQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKPLAPAGIPSNTAAAVTA 312 Query: 1274 VFGPGASSNNTTTSGFGF 1291 GPGA++ +S + Sbjct: 313 PPGPGAAAGAAASSAMTY 330 Score = 42.7 bits (99), Expect = 0.003 Identities = 74/345 (21%), Positives = 131/345 (37%), Gaps = 69/345 (20%) Query: 878 KPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS 937 +P T + G + ++ + + ++ F FG ++ +SG + GF +G+ Sbjct: 49 QPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGT---------------GFSLGIG 93 Query: 938 SDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTP 997 + +++ + + P G FG+ S N +SS +++ P Sbjct: 94 ASKLNLSNTAATPAMANPSG---FGLGS-------------SNLTNAISSTVTSSQGTAP 137 Query: 998 --FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIET 1055 F FG S P ++S GFSF G ST P S FN+G+ Sbjct: 138 TGFVFGPST------TSVAPATTSGGFSFTGG---STAQP----------SGFNIGSAGN 178 Query: 1056 KSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPAS-LPSASVFVLGRTEEKQQEPVTST 1114 + AP T + PAT + G +PA+ P+A++ G + ++ Sbjct: 179 SAQPTAPATLPFT-------PATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTS 231 Query: 1115 SLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFG 1174 S G C PV + G S K+ + S T + + A AT Sbjct: 232 SATTGLSL------CTPVTTAGAPTAGTQGFSLKAPGAASGTSTT---TSTAATATATTT 282 Query: 1175 AQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSS 1219 + +STT KP+ S+++++ A G G++ SS+ Sbjct: 283 SSSSTTGFALNLKPLAPAGIPSNTAAAVTAPPGPGAAAGAAASSA 327 Score = 31.2 bits (69), Expect = 7.7 Identities = 66/299 (22%), Positives = 107/299 (35%), Gaps = 33/299 (11%) Query: 369 TPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYP 428 T K + F S T F Q + STG T Q + +GF++ Sbjct: 20 TAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLAT--QTPATQTTGFTFG 77 Query: 429 NFSLPAAN-GLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSS--SLP 485 +L + G S G+G + + P + IS +TSS + P Sbjct: 78 TATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQGTAP 137 Query: 486 TFNFSSPEITTSSPSPINS-------SQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEAN 538 T P T+ +P+ + S A + + S ++ P + P +T A Sbjct: 138 TGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPA- 196 Query: 539 VLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598 ++ G T TA ++ + +L I+++ T + C TP P Sbjct: 197 ---ATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLC--TPVTTAGAP-- 249 Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLK 657 G+ LK+PG AS + + TAT A ++ SSS GF +LK Sbjct: 250 -----TAGTQGFSLKAPGAASGTSTTTSTAATAT--------ATTTSSSSTTGFALNLK 295 >gi|89276766 trophinin isoform 5 [Homo sapiens] Length = 1431 Score = 74.7 bits (182), Expect = 6e-13 Identities = 177/705 (25%), Positives = 250/705 (35%), Gaps = 108/705 (15%) Query: 824 SVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKS 883 S AS S+T +S GG+L S + + S++ P T + Sbjct: 764 STSASFSNTASISF--GGTLSTSSSFSSAASISFGCAHSTSTSFSSEASISFGGMPCTSA 821 Query: 884 GFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFK--------FGDQGG---- 931 F G +SS S + S++F G SS G TL++T F FG Sbjct: 822 SFSGGVSSSFSGPLSTSATFSGGASSGFGG---TLSTTAGFSGVLSTSTSFGSAPTTSTV 878 Query: 932 FKIGVSSDSGSINPMSEGFKFS-KPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLS 990 F +S+ +G +S F P FG + + + F LS+ +S Sbjct: 879 FSSALSTSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVS 938 Query: 991 -NPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSE------ 1043 S T FG G S S G FG G +N++ + + + TS Sbjct: 939 FGGSSSTSANFG----GTLSTSICFDGSPSTGAGFG-GALNTSASFGSVLNTSTGFGGAM 993 Query: 1044 NKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRT 1103 + S+ GT+ T S A GG N + S SV G Sbjct: 994 STSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSP 1053 Query: 1104 EEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSK-STFSFSMTKPSEKE 1162 STS FG + SFG + T S ST + P Sbjct: 1054 ---------STSAGFGGALNTNA-------SFGCAVSTSASFSGAVSTSACFSGAPITNP 1097 Query: 1163 SEQPAKATFA-FGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG-GGIFGSSTSSSN 1220 A +T A FG ST AD G +NS + P+TS GG G+S Sbjct: 1098 GFGGAFSTSAGFGGALSTAADFGGTP------SNSIGFGAAPSTSVSFGGAHGTSLCFGG 1151 Query: 1221 PPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGAS 1280 P + FG +SN ++ FG +S S S ++STG F FG G S Sbjct: 1152 APSTSLCFGSASN--TNLCFGGPPSTSACFSGATSPSFCDGPSTSTG-----FSFGNGLS 1204 Query: 1281 SNN------TTTSGFGFGATTTSSSAG-----SSFVFGTGPSA-----PSASPAFGANQT 1324 +N T++GFG G T++ +G S F G G SA P S FG Sbjct: 1205 TNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGFGGGLG 1264 Query: 1325 PTFGQSQGASQP--------NPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQ 1376 + G S G GFG + A F + + G +S+S FG Sbjct: 1265 TSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGGLSTSDG---FGS 1321 Query: 1377 QPSQS---------AFGSGTT--------PNSSSAFQFGSSTTNFNFTNNSPSGVFTFGA 1419 +P+ S FGSG+ P++S+ F G S+ F+ +GV F + Sbjct: 1322 RPNASFDRGLSTIIGFGSGSNTSTGFTGEPSTSTGFSSGPSSI-VGFSGGPSTGV-GFCS 1379 Query: 1420 NSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFSG 1464 ST S PS GF + A G + SG + G Sbjct: 1380 GPSTSGFSGGPSTGAGFGGGPNTGAGFGGGPSTSAGFGSGAASLG 1424 Score = 73.9 bits (180), Expect = 1e-12 Identities = 151/593 (25%), Positives = 216/593 (36%), Gaps = 117/593 (19%) Query: 960 KFGVSSESKPEEVKKDSKNDNFKFGLSS--GLSNPVSLTPFQFGVSNLGQEEKKEELPKS 1017 +F E++ +E S N NF G S+ G S+ S++ F + S Sbjct: 702 RFSFEIEARAQENADASTNVNFSRGASTRAGFSDGASIS---FNGA------------PS 746 Query: 1018 SSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS----ASVAPFTC--KTSEAK 1071 SS GFS G G+ AP+ + S S GT+ T S A+ F C TS + Sbjct: 747 SSGGFSGGPGITFGV-APSTSASFSNTASISFGGTLSTSSSFSSAASISFGCAHSTSTSF 805 Query: 1072 KEE-------MPATKGGFSFGNVEPASLP----------SASVFVLGRTEEKQQEPVTST 1114 E MP T FS G S P ++S F + V ST Sbjct: 806 SSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAGFSGVLST 865 Query: 1115 SLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFG 1174 S FG P VFS S T ++ F + S + FG Sbjct: 866 STSFGSA-----PTTSTVFSSALSTSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFG 920 Query: 1175 AQTSTTADQGAAKPVFSFLNNSSSSSS--------------TPATSAG-GGIFGSSTSSS 1219 T+ G SSS+S+ +P+T AG GG +S S Sbjct: 921 GSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDGSPSTGAGFGGALNTSASFG 980 Query: 1220 NPPVATFVFGQSSNPVSSSAFGNTAESST----SQSLLFSQDSKLATTSSTGTAV----- 1270 + + FG + + +S+ FG T +S S S S L T + G AV Sbjct: 981 SVLNTSTGFGGAMS--TSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGGAVSTNTD 1038 Query: 1271 ------TPFVFGPGASSNN------TTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPA 1318 T FG S++ T + FG +T++S +G+ AP +P Sbjct: 1039 FGGTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVSTSASFSGAVSTSACFSGAPITNPG 1098 Query: 1319 FGANQTPTFG--------QSQGASQPNPPGFGSISSS---------TALFPTGSQPAPPT 1361 FG + + G G + N GFG+ S+ T+L G+ Sbjct: 1099 FGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSVSFGGAHGTSLCFGGAPSTSLC 1158 Query: 1362 FGTVSSSSQPPVFGQQPSQSAFGSGTT-------PNSSSAFQFGSS-TTNFNFTN--NSP 1411 FG+ S+++ FG PS SA SG T P++S+ F FG+ +TN F N+ Sbjct: 1159 FGSASNTNL--CFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTNAGFGGGLNTS 1216 Query: 1412 SGVFTFGANSSTPAA-SAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463 +G FG T A S S S GF +A G G + G S Sbjct: 1217 AG---FGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGFGGGLGTS 1266 Score = 71.6 bits (174), Expect = 5e-12 Identities = 105/352 (29%), Positives = 157/352 (44%), Gaps = 51/352 (14%) Query: 1139 EQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSS 1198 E+ D+ + S FSF + +++ ++ F+ GA T GA+ SF N + Sbjct: 691 EELGDDAQAWSRFSFEIEARAQENADASTNVNFSRGASTRAGFSDGAS---ISF--NGAP 745 Query: 1199 SSSTPATSAGGGIFG--SSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESS----TSQSL 1252 SSS + G FG STS+S A+ FG + + +SS+F + A S S S Sbjct: 746 SSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLS--TSSSFSSAASISFGCAHSTST 803 Query: 1253 LFSQDSKLA------TTSSTGTAVTPFVFGP---GASSNNTTTSGFGFGATTTSSSAGSS 1303 FS ++ ++ T++S V+ GP A+ + +SGFG T S++AG S Sbjct: 804 SFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFG---GTLSTTAGFS 860 Query: 1304 FVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFG 1363 V T S SA PT ++ GFG I S++ F GS + +FG Sbjct: 861 GVLSTSTSFGSA---------PTTSTVFSSALSTSTGFGGILSTSVCF-GGSPSSSGSFG 910 Query: 1364 TVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNF---------TNNSPSGV 1414 S+S FG P S G G T ++S +F GSS+T+ NF + SPS Sbjct: 911 GTLSTS--ICFGGSPCTST-GFGGTLSTSVSFG-GSSSTSANFGGTLSTSICFDGSPSTG 966 Query: 1415 FTFGANSSTPAA-SAQPSGSGGFPFNQSPAAFTVGSNGKNVF--SSSGTSFS 1463 FG +T A+ + + S GF S +A G+ +V S GTS S Sbjct: 967 AGFGGALNTSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVS 1018 Score = 48.1 bits (113), Expect = 6e-05 Identities = 68/245 (27%), Positives = 98/245 (40%), Gaps = 20/245 (8%) Query: 1231 SSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFG 1290 S+N S A S S+ F+ + S G +T F P S++ + T+ Sbjct: 718 STNVNFSRGASTRAGFSDGASISFNGAPSSSGGFSGGPGIT-FGVAPSTSASFSNTASIS 776 Query: 1291 FGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTAL 1350 FG T ++SS+ SS + A S S +F + + +FG G + G +SSS Sbjct: 777 FGGTLSTSSSFSSAASISFGCAHSTSTSFSSEASISFG---GMPCTSASFSGGVSSSF-- 831 Query: 1351 FPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNS 1410 +G TF +SS FG S +A SG S+S FGS+ T +++ Sbjct: 832 --SGPLSTSATFSGGASSG----FGGTLSTTAGFSGVLSTSTS---FGSAPTTSTVFSSA 882 Query: 1411 PSGVFTFGANSSTPAA-SAQPSGSGGFPFNQSPAAFTVG----SNGKNVFSSSGTSFSGR 1465 S FG ST PS SG F S + G S G S+ SF G Sbjct: 883 LSTSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGS 942 Query: 1466 KIKTA 1470 +A Sbjct: 943 SSTSA 947 Score = 33.9 bits (76), Expect = 1.2 Identities = 36/154 (23%), Positives = 61/154 (39%), Gaps = 11/154 (7%) Query: 770 MTASSSSCTVTTGTLGFGDKFKRPI---GSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 + S+S +V + GFG G+ SVC + S ++ G Sbjct: 973 LNTSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGGA 1032 Query: 827 ASSSS----TVPVSLPSGGS----LGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAK 878 S+++ T+ S+ GGS G S+ C + + + + AC S Sbjct: 1033 VSTNTDFGGTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVSTSASFSGAVSTSACFSGA 1092 Query: 879 PGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSS 912 P T GF G ++S+ A S++ FG + S+S Sbjct: 1093 PITNPGFGGAFSTSAGFGGALSTAADFGGTPSNS 1126 >gi|161019170 mucin 5AC [Homo sapiens] Length = 6207 Score = 71.6 bits (174), Expect = 5e-12 Identities = 211/1005 (20%), Positives = 341/1005 (33%), Gaps = 190/1005 (18%) Query: 470 PVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSS 529 P P S T SS P + ++TT++ T+ STGS S+ Sbjct: 4200 PSTPATSSTATPSSTPGTTWILTKLTTTA----------------TTTESTGSTATPSST 4243 Query: 530 PIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKT 588 P T + PS+ T +VP TA S + +T P +S++A TT T+ K T Sbjct: 4244 P---GTTWILTEPSTTA-TVTVPTGSTATASSTQATAGTPHVSTTA---TTPTVTSSKAT 4296 Query: 589 PPEDCEGPFRPAEILKEGSVLDILKSPGFAS--PKIDSVAAQPTATSPVVYTRPAISSFS 646 P SPG A+ P + S A PTATS +T SS Sbjct: 4297 P----------------------FSSPGTATALPALRSTATTPTATS---FTAIPSSSLG 4331 Query: 647 SSGIGFGESLKAGSSWQCDT-----------CLLQNKVTDNKCIACQAAKLSPRDTAKQT 695 ++ ++ ++ T +L T + A S TA T Sbjct: 4332 TTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTT 4391 Query: 696 GIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVK 755 + T +G T +S G + PV W T P + PGT Sbjct: 4392 KVPTTTTTGFTVTPSSSPGTA-RTPPV---WISTT----TTPTTSGSTVTPSSVPGTTHT 4443 Query: 756 RALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVS 815 + T + A A+ SS T T+GT + Sbjct: 4444 PTVLTTTTTTVATGSMATPSSSTQTSGT------------------------THTPPVPN 4479 Query: 816 CMSEKPGSSVPASSSSTVPVSLPS--GGSLGLEKFKKPE-GSWDCELCLVQNKADSTKCL 872 + G S+ SS TV + S G+LG +P G+ ST L Sbjct: 4480 TTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPAL 4539 Query: 873 ACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGF 932 + T T++ +A S +++++ PS+T TST Sbjct: 4540 SSPHPSSRTTESPPSPGTTTPGHTTATSR------TTATATPSKTRTSTLLPSSPTSAPI 4593 Query: 933 KIGVSSDSGSINPMSEGFKFSKPI-----GDF----KFGVSSESKPEEVKKDSKNDNFKF 983 V++ SE +S P+ GDF + + E+ + Sbjct: 4594 TTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQP 4653 Query: 984 GLSSGLSNPVSLTPFQFGV--SNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVT 1041 G+ G V FG+ N Q K + F G STPA ++T + Sbjct: 4654 GVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMP 4713 Query: 1042 SENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLG 1101 S + + T T +A+ A+ G + + P + P V Sbjct: 4714 SSTPGTTWILTELTTTATTT---------------ASTGSTATPSSTPGTAPPPKVLT-- 4756 Query: 1102 RTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSS-----KSTFSFSMT 1156 P T+ + K + P+ S TK +S ST + T Sbjct: 4757 -------SPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGT 4809 Query: 1157 KPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSST 1216 P + + +T + TT ++ +++T ATS+ +ST Sbjct: 4810 LPEQTTTPVATMSTIHPSSTPETTHTSTVL---------TTKATTTRATSS------TST 4854 Query: 1217 SSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSSTGTAVTP- 1272 SS P + ++ +++A G TA S++ +L + TT+STG+ TP Sbjct: 4855 PSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPS 4914 Query: 1273 -------FVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTP 1325 + P ++ T +G A++T ++AG+ V T TP Sbjct: 4915 STPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTA-------------TTP 4961 Query: 1326 TFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVF---GQQPSQSA 1382 T S+ +P G+ ++ AL T + P +F + SSS + Q + +A Sbjct: 4962 TVTSSKATPSSSP---GTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTA 5018 Query: 1383 FGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAAS 1427 S TP+S+ S+ T +G + SSTP + Sbjct: 5019 TMSTATPSSTPETVHTSTVLTATATTTGATG--SVATPSSTPGTA 5061 Score = 57.8 bits (138), Expect = 8e-08 Identities = 222/1034 (21%), Positives = 342/1034 (33%), Gaps = 157/1034 (15%) Query: 470 PVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSS 529 P P S SS P + E+TT++ T+ STGS S+ Sbjct: 3053 PSTPATSSTAMPSSTPGTTWILTELTTTA----------------TTTESTGSTATPSST 3096 Query: 530 PIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKT 588 P T + PS+ T +VP TA S + +T P +S++A TT T+ K T Sbjct: 3097 P---GTTWILTEPSTTA-TVTVPTGSTATASSTQATAGTPHVSTTA---TTPTVTSSKAT 3149 Query: 589 PPEDCEGPFRPAEILKEGSVLDILKSPGFAS--PKIDSVAAQPTATSPVVYTRPAISSFS 646 P SPG A+ P + S A PTATS ++ Sbjct: 3150 P----------------------FSSPGTATALPALRSTATTPTATS--------FTAIP 3179 Query: 647 SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706 SS +G ++W + T + + T T T +G Sbjct: 3180 SSSLG--------TTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSV 3231 Query: 707 TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766 +S G K + T T + P + + T R T+T S Sbjct: 3232 ATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIP 3291 Query: 767 AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826 T T + + T TT G P S + S + + G S+ Sbjct: 3292 GTTHTPTVLTTTTTTVATG---SMATPSSSTQ-----TSGTTHTPPVPNTTATTHGRSLS 3343 Query: 827 ASSSSTVPVSLPSG--GSLGLEKFKKPE-GSWDCELCLVQNKADSTKCLACESAKPGTKS 883 SS TV + S G+LG +P G+ ST L+ T Sbjct: 3344 PSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTE 3403 Query: 884 GFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSI 943 T++ A S + ++++ PS+T TST V+ Sbjct: 3404 SPPSPGTTTPGHTRATSRT------TATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQ 3457 Query: 944 NPMSEGFKFSKPI-----GDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLS----NPVS 994 SE +S P+ GDF + + V + + G+ V Sbjct: 3458 CAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVV 3517 Query: 995 LTPFQFGV--SNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGT 1052 FG+ N Q K + F G STPA ++T S + + T Sbjct: 3518 ECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILT 3577 Query: 1053 IETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVT 1112 +T +A+ AT G + + P + P V T T Sbjct: 3578 EQTTAATTT---------------ATTGSTAIPSSTPGTAPPPKVLTSTATTP------T 3616 Query: 1113 STSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQP-AKATF 1171 +TS + PV + ++ T + +F+ T +++ P A + Sbjct: 3617 ATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMST 3676 Query: 1172 AFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG-IFGSSTSSSNPPVATFVFGQ 1230 + T T + ++SS STP+++ G I T+++ AT G Sbjct: 3677 IHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAAT---GP 3733 Query: 1231 SSNPVSSSAFGNT---AESSTSQSLLFSQDSKLATTSS----------TGTAVTPFVFGP 1277 ++ P SS G T E ST+ ++ S +S+ T TA TP V Sbjct: 3734 TATP--SSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISS 3791 Query: 1278 GA---SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGAS 1334 A SS T T+ +T T+ +A S + S +A TPT S Sbjct: 3792 RATPSSSPGTATALPALRSTATTPTATSVTAIPSS-SLGTAWTRLSQTTTPTATMSTATP 3850 Query: 1335 QPNPPGFGS----ISSSTALFPTGSQPAP-PTFGTVSSSSQPPV----FGQQPSQSA--- 1382 P + +++T TGS P T GT ++ P F PS S Sbjct: 3851 SSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTA 3910 Query: 1383 ------FGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS--TPAASAQPSGSG 1434 + TTP + + SS T + T A S TP++S Q SG+ Sbjct: 3911 LTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTT 3970 Query: 1435 GFPFNQSPAAFTVG 1448 P + A T G Sbjct: 3971 HTPPVPNTTATTHG 3984 Score = 55.1 bits (131), Expect = 5e-07 Identities = 74/293 (25%), Positives = 124/293 (42%), Gaps = 35/293 (11%) Query: 1155 MTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVF-SFLNNSSSSSSTPATSAGGGIFG 1213 +T P+ + +KAT + +T+TT PV S S+++S TP S+ G G Sbjct: 4755 LTSPATTPTATSSKATSSSSPRTATTL------PVLTSTATKSTATSVTPIPSSTLGTTG 4808 Query: 1214 SSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSST-GT---- 1268 + + PVAT + +P S+ +T+ T+++ S +T SST GT Sbjct: 4809 TLPEQTTTPVATM---STIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWIL 4865 Query: 1269 ------AVTPFVFGPGASSNNTT-TSGFGFGATTTSSSAGSSFVFGTGPSAPSAS----- 1316 A T GP A+ ++T T+ TTT+++ S+ T S P + Sbjct: 4866 TELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTE 4925 Query: 1317 PAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQ 1376 P+ A T G + AS S+TA PT T + SS P Sbjct: 4926 PSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPT------VTSSKATPSSSPGTATA 4979 Query: 1377 QPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQ 1429 P+ + + TTP ++S SS+ +T S + T +++TP+++ + Sbjct: 4980 LPALRS--TATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE 5030 Score = 48.1 bits (113), Expect = 6e-05 Identities = 210/1042 (20%), Positives = 349/1042 (33%), Gaps = 129/1042 (12%) Query: 454 TRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQ 513 T ++ ++P + VP + T ++ T P ++T++ +P +S T Sbjct: 4246 TTWILTEPSTTATVTVPTGSTATASSTQATAGT-----PHVSTTATTPTVTSSKAT---P 4297 Query: 514 MTSP-SSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISS 572 +SP ++T P + ++ +T +P SS+G T++ +++T + + ST P + Sbjct: 4298 FSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWT-RLSQTTTPTATMSTATPSSTP 4356 Query: 573 SAHHVTTVNSTNCKKT-------PPEDCEGPFRPAEI---LKEGSVLDILKSPGFA---- 618 H +TV +T T P G ++ G + SPG A Sbjct: 4357 ETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPP 4416 Query: 619 -------SPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQN 671 +P P++ +T P + + +++ + G SS Q + Sbjct: 4417 VWISTTTTPTTSGSTVTPSSVPGTTHT-PTVLTTTTTTVATGSMATPSSSTQ-TSGTTHT 4474 Query: 672 KVTDNKCIACQAAKLSPRD--TAKQTGIE-TPNKSGKTTLSASGTGFGDKFKPVIGTWDC 728 N LSP T + T G T ++ TG GT Sbjct: 4475 PPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQH 4534 Query: 729 DTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGD 788 T + + P P PGT T T S T TA+ S T TL Sbjct: 4535 STPAL-SSPHPSSRTTESPPSPGTTTPGHTTAT----SRTTATATPSK--TRTSTLLPSS 4587 Query: 789 KFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKF 848 PI + + C +P + + P+ PSGG Sbjct: 4588 PTSAPITTVVTTGC-----------------EPQCAWSEWLDYSYPMPGPSGGDFDTYSN 4630 Query: 849 KKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKG------FDTSSSSSNSAASSS 902 + G CE L +C A A+PG G G D N Sbjct: 4631 IRAAGGAVCEQPL------GLECRA--QAQPGVPLGELGQVVECSLDFGLVCRNREQVGK 4682 Query: 903 FKFGVS--------SSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSK 954 FK + + PS TS+ G I + + S G + Sbjct: 4683 FKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATP 4742 Query: 955 PIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEEL 1014 + P+ + + ++ S+P + T S + Sbjct: 4743 -----SSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVT 4797 Query: 1015 PKSSSAGFSFGTGVINSTP--APANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKK 1072 P SS + GT +T A +TI S + + T+ T A+ T TS Sbjct: 4798 PIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTS---- 4853 Query: 1073 EEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEP--------VTSTSLVFGKKADN 1124 P++ G ++ E + + + G T P +T+T+ Sbjct: 4854 --TPSSTPGTTWILTE-LTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGST 4910 Query: 1125 EEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFA-FGAQTSTTADQ 1183 P P ++ +E + + T S + ++ + P +T A TS+ A Sbjct: 4911 ATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATP 4970 Query: 1184 GAAKPVFSFLNNSSSSSSTPATSAGGGIFGSS-------TSSSNPPVATFVFGQSSNPVS 1236 ++ + L S+++TP ++ I SS S + P AT ++ P S Sbjct: 4971 SSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATM---STATPSS 5027 Query: 1237 SSAFGNTAESSTSQSLLFSQDSKLATTSST-GTAVT---PFVFGPGASSNNTTTSGFGF- 1291 + +T+ T+ + +AT SST GTA T P G ++ +++ G Sbjct: 5028 TPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALT 5087 Query: 1292 GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALF 1351 TTT S S+ + P S T T + A+ + G+ T L Sbjct: 5088 PPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSST--LGTTRILTELT 5145 Query: 1352 PTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSP 1411 T + A T T + SS P S + P S+A SST T ++P Sbjct: 5146 TTATTTA-ATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTA--TASSTLG---TAHTP 5199 Query: 1412 SGVFTFGANSSTPAASAQPSGS 1433 V T A T AS PS S Sbjct: 5200 KVVTTM-ATMPTATASTVPSSS 5220 Score = 47.8 bits (112), Expect = 8e-05 Identities = 67/286 (23%), Positives = 111/286 (38%), Gaps = 16/286 (5%) Query: 1177 TSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVS 1236 TS+TA ++ P +++ ++++T S G SST + PP ++ P + Sbjct: 4707 TSSTA-MPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLT-SPATTPTA 4764 Query: 1237 SSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTT 1296 +S+ ++ S + + L S T ST T+VTP S+ T+G TTT Sbjct: 4765 TSSKATSSSSPRTATTLPVLTS--TATKSTATSVTPI------PSSTLGTTGTLPEQTTT 4816 Query: 1297 SSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQ 1356 + S+ + P S T T S ++ + PG I + T + Sbjct: 4817 PVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTA 4876 Query: 1357 PAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFT 1416 P T + SS P + + T S+A + T + T S + T Sbjct: 4877 ATGP---TATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVT 4933 Query: 1417 FGANSSTPAASAQPSGSGGFPFNQSPAAF-TVGSNGKNVFSSSGTS 1461 S+ A+S Q + G P + A TV S+ SS GT+ Sbjct: 4934 VPTGSTATASSTQ--ATAGTPHVSTTATTPTVTSSKATPSSSPGTA 4977 Score = 45.4 bits (106), Expect = 4e-04 Identities = 79/337 (23%), Positives = 124/337 (36%), Gaps = 55/337 (16%) Query: 1161 KESEQPAKATFAFGAQTSTTADQGAAKPVFS-----FLNNSSSSSSTPATSAGGGIFGSS 1215 +E Q + + FG G K F+ F N STPATS+ ++ Sbjct: 4156 RELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSS------TA 4209 Query: 1216 TSSSNPPVATFVFGQSSNPVSSSAFGNTA-------------ESSTSQSLLFSQDSKLAT 1262 T SS P + ++ ++ + G+TA E ST+ ++ S Sbjct: 4210 TPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATA 4269 Query: 1263 TSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPS----ASPA 1318 +S+ TA TP V + T++ F + T+++ + T P+A S S + Sbjct: 4270 SSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSS 4329 Query: 1319 FG---------ANQTPTFGQSQGASQPNPPGFGSISSSTALF--PTGSQPAP-PTFGTVS 1366 G T T + +S P ++ ++TA TGS P T GT Sbjct: 4330 LGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAH 4389 Query: 1367 SSSQPPV----FGQQPSQSA---------FGSGTTPNSSSAFQFGSSTTNFNFTNNSPSG 1413 ++ P F PS S + TTP +S + SS T + Sbjct: 4390 TTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTT 4449 Query: 1414 VFTFGANSS--TPAASAQPSGSGGFPFNQSPAAFTVG 1448 T A S TP++S Q SG+ P + A T G Sbjct: 4450 TTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHG 4486 Score = 44.7 bits (104), Expect = 7e-04 Identities = 77/330 (23%), Positives = 125/330 (37%), Gaps = 35/330 (10%) Query: 1146 SSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPAT 1205 SS ++ +TKP+ + + + A T TA + +SS +TP++ Sbjct: 2591 SSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSS 2650 Query: 1206 SAGGGI-FGSSTSSSNPPVATFVFGQSSNPVSSSAFGNT-----AESSTSQSLLFSQDSK 1259 S G + S++ P AT S P+ SS+ G T ++ + ++ + S Sbjct: 2651 SPGTATALPALRSTATTPTAT-----SVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSS 2705 Query: 1260 LATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAF 1319 T+ T T +T GA+ + T S A TT ++ F + PS+SP Sbjct: 2706 TPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGF---TATPSSSPGT 2762 Query: 1320 GAN-----QTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQ---- 1370 T T ++G++ G+ ++T L T + A + T SSS+Q Sbjct: 2763 ALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGT 2822 Query: 1371 ---PPVFGQQ--------PSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGA 1419 PPV P S T S+++ G++ T S + T G Sbjct: 2823 THTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGT 2882 Query: 1420 NS-STPAASAQPSGSGGFPFNQSPAAFTVG 1448 STPA S+ S SP T G Sbjct: 2883 TQHSTPALSSPHPSSRTTESPPSPGTTTPG 2912 Score = 44.3 bits (103), Expect = 9e-04 Identities = 105/471 (22%), Positives = 180/471 (38%), Gaps = 69/471 (14%) Query: 1017 SSSAGFSFGTGVINSTPAPANTIVTS---ENKSSFNLGTIETKSASVAPFTCKTSEAKKE 1073 +S+A S T V TP P++T+ T+ +++ + T+ T S P T TS Sbjct: 4785 TSTATKSTATSV---TPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTT 4841 Query: 1074 EMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVF 1133 + T+ S P+S P + + T +T+ G A P P Sbjct: 4842 KATTTRATSSTST--PSSTPGTTWILTELTT------AATTTAATGPTAT---PSSTPGT 4890 Query: 1134 SFGNSEQTKDENSSKSTFSFS-----------MTKPSEKESEQPAKATFAFGAQTSTTAD 1182 ++ +E T ++ ST S + +T+PS + + A + T TA Sbjct: 4891 TWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAG 4950 Query: 1183 QGAAKPVFSFLNNSSSSSSTPATSAGGGI-FGSSTSSSNPPVATFVFGQSSNPVSSSAFG 1241 + +SS +TP++S G + S++ P AT S + SS+ G Sbjct: 4951 TPHVSTTAT-TPTVTSSKATPSSSPGTATALPALRSTATTPTAT-----SFTAIPSSSLG 5004 Query: 1242 NTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAG 1301 T +++ S+ T ++T + TP +S+ T + AT T++ A Sbjct: 5005 TT----------WTRLSQTTTPTATMSTATP------SSTPETVHTSTVLTATATTTGAT 5048 Query: 1302 SSFVFGTGPSAPSASPAFG-ANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPP 1360 S + PS++P + PT + + P S S TAL P + P Sbjct: 5049 GSV------ATPSSTPGTAHTTKVPTTTTTGFTATP------SSSPGTALTPPTTTPM-S 5095 Query: 1361 TFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGAN 1420 T T+ +SS P + + T +S+A + T T + + T A Sbjct: 5096 TMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTAT-TTAAT 5154 Query: 1421 SSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSS--GTSFSGRKIKT 1469 ST S+ P G+ S A + G +SS GT+ + + + T Sbjct: 5155 GSTATLSSTP-GTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTT 5204 Score = 40.8 bits (94), Expect = 0.010 Identities = 63/278 (22%), Positives = 102/278 (36%), Gaps = 34/278 (12%) Query: 1190 FSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSS-------SAFGN 1242 +S ++ ++SST S+ G T + T G ++ P S+ Sbjct: 2575 YSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTT 2634 Query: 1243 TAESSTSQSLLFSQDSKLAT-----------TSSTGTAVTPFVFGPGASSNNTTTSGFGF 1291 TA + T S + S T T+ T T+VTP P +S T T Sbjct: 2635 TATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPI---PSSSLGTTWTR---L 2688 Query: 1292 GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALF 1351 TTT ++ S+ + P S A T T A+ + PG + Sbjct: 2689 SQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTT 2748 Query: 1352 PTGSQPAPPTFGTVSSSSQPPVF-GQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNS 1410 TG P + + ++ PPV+ + + GS TP+S +T + Sbjct: 2749 TTGFTATPSS--SPGTALTPPVWISTTTTPTTRGSTVTPSS-----IPGTTHTATVLTTT 2801 Query: 1411 PSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVG 1448 + V T + +TP++S Q SG+ P + A T G Sbjct: 2802 TTTVAT--GSMATPSSSTQTSGTTHTPPVPNTMATTHG 2837 Score = 38.1 bits (87), Expect = 0.063 Identities = 79/338 (23%), Positives = 123/338 (36%), Gaps = 57/338 (16%) Query: 1161 KESEQPAKATFAFGAQTSTTADQGAAKPVFS-----FLNNSSSSSSTPATSAGGGIFGSS 1215 +E Q + + FG G K F+ F N STPATS+ SS Sbjct: 3009 RELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTA--MPSS 3066 Query: 1216 TSSSN------PPVATFVFGQSSNPVSSSAFGNT---AESSTSQSLLFSQDSKLATTSST 1266 T + AT S SS G T E ST+ ++ S +S+ Sbjct: 3067 TPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQ 3126 Query: 1267 GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSA------PSAS---- 1316 TA TP V + T++ F + T+++ + T P+A PS+S Sbjct: 3127 ATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTT 3186 Query: 1317 -PAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPP--- 1372 TPT S P ++ +ST L T + G+V++ S P Sbjct: 3187 WTRLSQTTTPTATMSTATPSSTPE---TVHTSTVLTTTATTTG--ATGSVATPSSTPGTA 3241 Query: 1373 -----------VFGQQPSQSAFGSGTTP----NSSSAFQFGSSTTNFNF--TNNSPSGVF 1415 F PS S + T P +++ GS+ T + T ++P+ + Sbjct: 3242 HTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLT 3301 Query: 1416 T-----FGANSSTPAASAQPSGSGGFPFNQSPAAFTVG 1448 T + +TP++S Q SG+ P + A T G Sbjct: 3302 TTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHG 3339 Score = 35.0 bits (79), Expect = 0.54 Identities = 37/161 (22%), Positives = 64/161 (39%), Gaps = 13/161 (8%) Query: 479 ITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEAN 538 +T SS+P ++ +TT++ + S A + TS ++ P+ ++ +T Sbjct: 3930 VTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTA----TTHGR 3985 Query: 539 VLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598 LPPSS + + T+ + G++ EP +S H ST TP P Sbjct: 3986 SLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTS-HTPAATTSTTQHSTPALSSPHP-- 4042 Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTR 639 + SPG +P ++ TAT+ TR Sbjct: 4043 ------SSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTR 4077 Score = 34.7 bits (78), Expect = 0.70 Identities = 62/272 (22%), Positives = 100/272 (36%), Gaps = 47/272 (17%) Query: 476 SLPITSSSLPTFNFSSPEITTSSPSPINSSQ---ALTNKVQMTSPSSTGSPMFKFSSPIV 532 S P T+++LP ++ T +S +PI SS T Q T+P++T S S+P Sbjct: 2650 SSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPET 2709 Query: 533 KSTE-------------ANVLPPSS---IGFTFSVPVAKTAELSGSSST-----LEPIIS 571 T +V PSS T VP T + + S+ L P + Sbjct: 2710 AHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVW 2769 Query: 572 SSAHHVTTVNSTNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTA 631 S TT +T P G A +L + + + A+P + T Sbjct: 2770 IS---TTTTPTTRGSTVTPSSIPGTTHTATVLT--TTTTTVATGSMATP------SSSTQ 2818 Query: 632 TSPVVYTRPAISSFSSSGIGFGESLKAGS------SWQCDT--CLLQNKVTDNKCIACQA 683 TS +T P ++ +++ G SL S +W T L +T+ + Sbjct: 2819 TSGTTHTPPVPNTMATT---HGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHT 2875 Query: 684 AKLSPRDTAKQT-GIETPNKSGKTTLSASGTG 714 + T T + +P+ S +TT S G Sbjct: 2876 LAATTGTTQHSTPALSSPHPSSRTTESPPSPG 2907 Score = 34.7 bits (78), Expect = 0.70 Identities = 170/830 (20%), Positives = 279/830 (33%), Gaps = 161/830 (19%) Query: 691 TAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKP 750 T + T T +G T + +S G K + T T + K + +P+ Sbjct: 3577 TEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTAT------SSKATSSSSPRT 3630 Query: 751 GTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAED 810 T + LT T +A + T S TTGTL ++ P+ + S S+ E Sbjct: 3631 ATTLP-VLTSTATKSTATSFTPIPSFTLGTTGTLP--EQTTTPMATM--STIHPSSTPET 3685 Query: 811 NKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDC-ELCLVQNKADST 869 + ++ K ++ A+SS + P S P +W EL +T Sbjct: 3686 THTSTVLTTK-ATTTRATSSMSTPSSTPGT-------------TWILTELTTAATTTAAT 3731 Query: 870 KCLACESAKPGT-----KSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNF 924 A S+ PGT + T + S + ASS+ +++G + LTST Sbjct: 3732 GPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASST------RATAGTLKVLTSTATT 3785 Query: 925 KFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFG 984 S + S G + P Sbjct: 3786 P----------TVISSRATPSSSPGTATALP----------------------------A 3807 Query: 985 LSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANT--IVTS 1042 L S + P + + S+LG + L ++++ + T +STP +T ++T+ Sbjct: 3808 LRSTATTPTATSVTAIPSSSLGTAWTR--LSQTTTPTATMSTATPSSTPETVHTSTVLTT 3865 Query: 1043 ENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGR 1102 ++ G++ T S++ P T T++ T GF+ P+S P ++ Sbjct: 3866 TTTTTRATGSVATPSST--PGTAHTTKVPT----TTTTGFT---ATPSSSPGTAL----- 3911 Query: 1103 TEEKQQEPV-TSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEK 1161 PV ST+ + P P + + T ++ + + SM PS Sbjct: 3912 -----TPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLT---TTTTTVATGSMATPSS- 3962 Query: 1162 ESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGS------S 1215 S Q + T +T G + P +S + T TSA GI G+ S Sbjct: 3963 -STQTSGTTHTPPVPNTTATTHGRSLPP-----SSPHTVRTAWTSATSGILGTTHITEPS 4016 Query: 1216 TSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVF 1275 T +S+ P AT Q S P SS ++ + + S + TS T TP Sbjct: 4017 TVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKT 4076 Query: 1276 GPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQT----------- 1324 ++ TS TT ++ S P P+ G T Sbjct: 4077 RTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAV 4136 Query: 1325 ---PTFGQSQGASQPNPP--GFGSISSSTALFPT-------------------------- 1353 P + + +QP P G + + F Sbjct: 4137 CEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNY 4196 Query: 1354 GSQPA-PPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPS 1412 G P+ P T T + SS P + + T S+A + T + T S + Sbjct: 4197 GHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTT 4256 Query: 1413 GVFTFGANSSTPAASAQPSGSGGFPFNQSPAAF-TVGSNGKNVFSSSGTS 1461 T S+ A+S Q + G P + A TV S+ FSS GT+ Sbjct: 4257 ATVTVPTGSTATASSTQ--ATAGTPHVSTTATTPTVTSSKATPFSSPGTA 4304 Score = 34.3 bits (77), Expect = 0.91 Identities = 53/227 (23%), Positives = 79/227 (34%), Gaps = 14/227 (6%) Query: 1232 SNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGF 1291 S P +SS ++ T+ +L + TT+STG+ TP PG + + Sbjct: 4703 STPATSSTAMPSSTPGTTW-ILTELTTTATTTASTGSTATP-SSTPGTAPPPKVLTSPAT 4760 Query: 1292 GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALF 1351 T TSS A SS + P + P + T + S P P S +T Sbjct: 4761 TPTATSSKATSS----SSPRTATTLPVLTSTATKSTATS---VTPIP---SSTLGTTGTL 4810 Query: 1352 PTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSP 1411 P + T T+ SS P S TT ++S+ SST + Sbjct: 4811 PEQTTTPVATMSTIHPSSTPET--THTSTVLTTKATTTRATSSTSTPSSTPGTTWILTEL 4868 Query: 1412 SGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSS 1458 + T A + A + G+ + A T S G SS Sbjct: 4869 TTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSS 4915 >gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens] Length = 587 Score = 67.8 bits (164), Expect = 7e-11 Identities = 118/499 (23%), Positives = 189/499 (37%), Gaps = 89/499 (17%) Query: 1016 KSSSAGFSFGTGVINSTPAPANTIV---TSENKSSFNLGTIETKSASVAPFTCKTSEAKK 1072 + S+ S T I+S P+ + +V TS + S + T +S + S A Sbjct: 14 EESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASH 73 Query: 1073 EEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPV 1132 AT G + + + SV +LG E P++S S+ E P Sbjct: 74 SSQDAT------GTIVLPARSTTSV-LLG---ESTTSPISSGSM---------ETTALP- 113 Query: 1133 FSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSF 1192 S T + +TF S P+ S PA T + ++ STT+ ++P Sbjct: 114 ----GSTTTPGLSEKSTTFHSSPRSPATTLS--PASTTSSGVSEESTTSH---SRP---- 160 Query: 1193 LNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSL 1252 S+ +++ P ++ G+ ST+S + P +T + P S++ G + ES+TS S Sbjct: 161 --GSTHTTAFPDSTTTPGLSRHSTTSHSSPGST---DTTLLPASTTTSGPSQESTTSHSS 215 Query: 1253 LFSQDSKLATTSST----GTAVTPFVFGPGASS-----NNTTTSGFGFGATTTSSSAGS- 1302 S D+ L+ S+T G T F PG++ ++TT+SG +T SS GS Sbjct: 216 PGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP 275 Query: 1303 ----SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSI-------------S 1345 S T P S AF + T + P+PP + S Sbjct: 276 RTTLSPASSTSPGLQGESTAFQTHPASTH------TTPSPPSTATAPVEESTTYHRSPGS 329 Query: 1346 SSTALFPTGS------------QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSS 1393 + T FP S +P GT SS+ G S S + P S+ Sbjct: 330 TPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGVSEESST--SHSQPGSTH 387 Query: 1394 AFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKN 1453 F STT + + + G+ +T + P G+ P S + S+ Sbjct: 388 TTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSSTPT 447 Query: 1454 V-FSSSGTSFSGRKIKTAV 1471 FS+S T+ + T V Sbjct: 448 THFSASSTTLGRSEESTTV 466 Score = 54.7 bits (130), Expect = 7e-07 Identities = 106/468 (22%), Positives = 175/468 (37%), Gaps = 53/468 (11%) Query: 1010 KKEELPKSSSAGFSFGTGVINSTPAPANTIVT--SENKSSFNLGTIETKSASVAPFTCKT 1067 + EE S S+ + GT V+ PA + T V S + G++ET + + T Sbjct: 65 RSEESTASHSSQDATGTIVL---PARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGL 121 Query: 1068 SEAK-----KEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKA 1122 SE PAT + PAS S+ V T + P ++ + F Sbjct: 122 SEKSTTFHSSPRSPAT-------TLSPASTTSSGVSEESTTSHSR--PGSTHTTAFPDST 172 Query: 1123 DNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTAD 1182 S + T ST + ++ S P A ++T Sbjct: 173 TTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALS 232 Query: 1183 QGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSST---SSSNPPVATFVFGQSSNPVSSSA 1239 G F S+ ++ P ++ GI +ST SS+ P T +P SS++ Sbjct: 233 FGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL------SPASSTS 286 Query: 1240 FGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPG--ASSNNTTTSGFGFGATTTS 1297 G ES+ Q+ S T S TA P S +T T+ F ++TTS Sbjct: 287 PGLQGESTAFQT---HPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFP-ASSTTS 342 Query: 1298 SSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQP 1357 + S +F + P A +P+ A+ T + + ++ + PG S+ T FP + Sbjct: 343 GHSEKSTIFHSSPDASGTTPS-SAHSTTSGVSEESSTSHSQPG----STHTTAFPDST-- 395 Query: 1358 APPTFGTVSSSSQPPV---FGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGV 1414 T S SQ P Q +++ + +P ++A STT + +++P+ Sbjct: 396 ------TTSGLSQEPTTSHSSQGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSSTPT-- 447 Query: 1415 FTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSF 1462 F A+S+T S + + P + A GS S T+F Sbjct: 448 THFSASSTTLGRSEESTTVHSSPGSTETTALP-GSTTTAGLSEKSTTF 494 Score = 52.4 bits (124), Expect = 3e-06 Identities = 122/558 (21%), Positives = 200/558 (35%), Gaps = 64/558 (11%) Query: 815 SCMSEKPGS--SVPASSSST-VPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKC 871 S + E+P S S P S+++T P S + G E+ S D +V +T Sbjct: 35 SALVEEPTSYHSSPGSTATTHFPDSSTTSGRS--EESTASHSSQDATGTIVLPARSTTSV 92 Query: 872 LACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGG 931 L ES SG S+ + S SS P+ TL+ G Sbjct: 93 LLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSG---- 148 Query: 932 FKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSN 991 VS +S + + S+P + + + S + G + Sbjct: 149 ----VSEESTTSH--------SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLL 196 Query: 992 PVSLT---PFQFGVSNLGQEEKKEE-LPKSSSAGFSFG--TGVINSTPAPANTIVTSENK 1045 P S T P Q ++ + L S+ SFG + +S+P +T + ++ Sbjct: 197 PASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDST 256 Query: 1046 SSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEE 1105 +S + T+ S T P +G + PAS T Sbjct: 257 TSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAS-----------THT 305 Query: 1106 KQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQ 1165 P T+T+ V + P P F S T +S KST S S Sbjct: 306 TPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSG-HSEKSTIFHSSPDASGTTPSS 364 Query: 1166 PAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSS--SSTPATS--AGGGIFGSSTSSSNP 1221 T ++ST+ Q + +F +++++S S P TS + G + ++ +P Sbjct: 365 AHSTTSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSP 424 Query: 1222 PVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS 1281 P G ++ PV S ++ SST + FS S S T V +S Sbjct: 425 P------GTTAAPVEVSTTYHSRPSSTPTTH-FSASSTTLGRSEESTTVH-------SSP 470 Query: 1282 NNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGF 1341 +T T+ G+TTT+ + S F + P +P + + A+ T + + + + PG Sbjct: 471 GSTETTALP-GSTTTAGLSEKSTTFYSSPRSPDTTLS-PASTTSSGVSEESTTSHSRPG- 527 Query: 1342 GSISSSTALFPTGSQPAP 1359 S+ T FP GS P Sbjct: 528 ---STHTTAFP-GSTTMP 541 Score = 48.9 bits (115), Expect = 4e-05 Identities = 82/305 (26%), Positives = 124/305 (40%), Gaps = 58/305 (19%) Query: 1176 QTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPV 1235 ++ TT+ +G S + + + SS P+T++ +S SS AT F P Sbjct: 5 ESDTTSGRGEESTT-SHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHF-----PD 58 Query: 1236 SSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATT 1295 SS+ G + ES+ S S SQD+ TGT V P +TTS G+ Sbjct: 59 SSTTSGRSEESTASHS---SQDA-------TGTIVLPARSTTSVLLGESTTSPISSGSME 108 Query: 1296 TSSSAGS---------SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISS 1346 T++ GS S F + P +P A+ A+ T + + + + PG S+ Sbjct: 109 TTALPGSTTTPGLSEKSTTFHSSPRSP-ATTLSPASTTSSGVSEESTTSHSRPG----ST 163 Query: 1347 STALFP------------TGSQPAPPTFGT----VSSSSQPPVFGQQPSQSAFGSGTT-- 1388 T FP T S +P + T S+++ P S S+ GS T Sbjct: 164 HTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTAL 223 Query: 1389 -PNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPA-----ASAQPSGSGGFP-FNQS 1441 P S++A FG +T F ++SP T ST + AS + S G P S Sbjct: 224 SPGSTTALSFGQESTTF---HSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLS 280 Query: 1442 PAAFT 1446 PA+ T Sbjct: 281 PASST 285 Score = 44.3 bits (103), Expect = 9e-04 Identities = 128/562 (22%), Positives = 211/562 (37%), Gaps = 59/562 (10%) Query: 769 TMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPAS 828 T + SS++ T+++ + P + + D+ S SE+ +S +S Sbjct: 17 TTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTAS-HSS 75 Query: 829 SSSTVPVSLPSGGSLGL---EKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGF 885 +T + LP+ + + E P S E T L + PG Sbjct: 76 QDATGTIVLPARSTTSVLLGESTTSPISSGSME----------TTALPGSTTTPGLSEKS 125 Query: 886 KGFDTS--SSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSI 943 F +S S ++ + +S+ GVS S+ ST F D G+S S + Sbjct: 126 TTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTP-GLSRHS-TT 183 Query: 944 NPMSEGFKFSK--PIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFG 1001 + S G + P G S ES S + G ++ LS T F Sbjct: 184 SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFH-- 241 Query: 1002 VSNLGQEEKKEELPKSSSAGF-SFGTGVINSTPAPANTIVTSENKSSFNLG---TIETKS 1057 S+ G ++S+G T V +ST +P T+ + + S G +T Sbjct: 242 -SSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHP 300 Query: 1058 ASV--APFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS 1115 AS P T+ A EE +T S G+ P++S G +E+ ST Sbjct: 301 ASTHTTPSPPSTATAPVEE--STTYHRSPGSTPTTHFPASST-TSGHSEK-------STI 350 Query: 1116 LVFGKKADNEEPKCQPVFSFGNSEQTKDENS---SKSTFSFSMTKPSEKESEQPAKATFA 1172 A P + G SE++ +S S T +F + + S++P + + Sbjct: 351 FHSSPDASGTTPSSAHSTTSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSS 410 Query: 1173 FGA-----QTSTTADQGAAKPVFSFLNNSSSSSSTPAT--SAGGGIFGSSTSSSNPPVAT 1225 G+ T+ + A PV S SSTP T SA G S S+ + Sbjct: 411 QGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP 470 Query: 1226 FVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTT 1285 ++ P S++ G + +S+T S S D+ L+ S+T + V S +T Sbjct: 471 GSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGV----------SEEST 520 Query: 1286 TSGFGFGATTTSSSAGSSFVFG 1307 TS G+T T++ GS+ + G Sbjct: 521 TSHSRPGSTHTTAFPGSTTMPG 542 Score = 37.0 bits (84), Expect = 0.14 Identities = 101/437 (23%), Positives = 157/437 (35%), Gaps = 58/437 (13%) Query: 94 SNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTS 153 ++ T ++ E S++ ST +TA +PD T P L R ST+ Sbjct: 142 ASTTSSGVSEESTTSHSRPGSTHTTA--FPDSTTTPGLSRH----------------STT 183 Query: 154 SAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASDKDITVSKNTSLPPLWSPEAE 213 S GS+ +L+ ST+ STTS S ++D ++ T+L Sbjct: 184 SHSSPGSTDTTLLPA---STTTSGPSQESTTSHSSPGSTDTALSPGSTTAL--------- 231 Query: 214 RSHSLSQHTATSSKKPAFNLSAFGTLSP-SLGNSSILKTSQLGDSPFYPGKTTYGGAAAA 272 S Q + T P S TL P S +S I++ S S +TT A++ Sbjct: 232 ---SFGQESTTFHSSPG---STHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASST 285 Query: 273 VRQSKLRNTPYQA-PVRRQMKAKQLSAQSYGVTSSTA-RRILQSLEKMSSPLADAKRIPS 330 + +T +Q P S + V ST R S P + S Sbjct: 286 SPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHS 345 Query: 331 IVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVSIATNRSVYFKPSLTPS 390 S+ +S D SG + + V + +P S T F S T S Sbjct: 346 EKSTIFHSSPDASGTTPSSAHSTTSGVSEE----SSTSHSQPGSTHTTA---FPDSTTTS 398 Query: 391 GEFRKTNQRIDNKCSTGYEKNMTP---GQNREQRESGFSYPN--FSLPAANGLSSGVGGG 445 G ++ ++ ST + TP G E +Y + S P + +S G Sbjct: 399 GLSQEPTTSHSSQGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLG 458 Query: 446 GGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSS 505 R E + V S P E LP + S T +SSP ++ SP +++ Sbjct: 459 ----RSEESTTVHSSP---GSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTT 511 Query: 506 QALTNKVQMTSPSSTGS 522 + ++ TS S GS Sbjct: 512 SSGVSEESTTSHSRPGS 528 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.307 0.123 0.350 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 62,421,546 Number of Sequences: 37866 Number of extensions: 3266092 Number of successful extensions: 22627 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 113 Number of HSP's successfully gapped in prelim test: 584 Number of HSP's that attempted gapping in prelim test: 13909 Number of HSP's gapped (non-prelim): 4985 length of query: 1475 length of database: 18,247,518 effective HSP length: 115 effective length of query: 1360 effective length of database: 13,892,928 effective search space: 18894382080 effective search space used: 18894382080 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.