Guide to the Human Genome
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Search of human proteins with 24430146

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24430146 nucleoporin 153kDa [Homo sapiens]
         (1475 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24430146 nucleoporin 153kDa [Homo sapiens]                        2928   0.0  
gi|150418007 RAN binding protein 2 [Homo sapiens]                     184   5e-46
gi|91982772 mucin 17 [Homo sapiens]                                   134   8e-31
gi|33946327 nucleoporin 214kDa [Homo sapiens]                         127   1e-28
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                       100   2e-20
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            99   2e-20
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            99   2e-20
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            99   2e-20
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            99   2e-20
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            99   2e-20
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            99   2e-20
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]            99   2e-20
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]            99   2e-20
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]            99   2e-20
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    99   3e-20
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ...    92   5e-18
gi|161016767 mucin 21 [Homo sapiens]                                   91   1e-17
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]    89   4e-17
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    87   2e-16
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]           84   8e-16
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    83   2e-15
gi|56549643 nucleoporin 98kD isoform 3 [Homo sapiens]                  78   6e-14
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        77   2e-13
gi|24497609 nucleoporin 62kDa [Homo sapiens]                           75   6e-13
gi|24497607 nucleoporin 62kDa [Homo sapiens]                           75   6e-13
gi|24497605 nucleoporin 62kDa [Homo sapiens]                           75   6e-13
gi|24497603 nucleoporin 62kDa [Homo sapiens]                           75   6e-13
gi|89276766 trophinin isoform 5 [Homo sapiens]                         75   6e-13
gi|161019170 mucin 5AC [Homo sapiens]                                  72   5e-12
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]             68   7e-11

>gi|24430146 nucleoporin 153kDa [Homo sapiens]
          Length = 1475

 Score = 2928 bits (7591), Expect = 0.0
 Identities = 1475/1475 (100%), Positives = 1475/1475 (100%)

Query: 1    MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN 60
            MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN
Sbjct: 1    MASGAGGVGGGGGGKIRTRRCHQGPIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFN 60

Query: 61   KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS 120
            KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS
Sbjct: 61   KNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTAS 120

Query: 121  NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN 180
            NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN
Sbjct: 121  NYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDN 180

Query: 181  ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS 240
            ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS
Sbjct: 181  ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS 240

Query: 241  PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS 300
            PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS
Sbjct: 241  PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS 300

Query: 301  YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ 360
            YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ
Sbjct: 301  YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQ 360

Query: 361  YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ 420
            YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ
Sbjct: 361  YPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQ 420

Query: 421  RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT 480
            RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT
Sbjct: 421  RESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPIT 480

Query: 481  SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL 540
            SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL
Sbjct: 481  SSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVL 540

Query: 541  PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPA 600
            PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPA
Sbjct: 541  PPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPA 600

Query: 601  EILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGS 660
            EILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGS
Sbjct: 601  EILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGS 660

Query: 661  SWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFK 720
            SWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFK
Sbjct: 661  SWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFK 720

Query: 721  PVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVT 780
            PVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVT
Sbjct: 721  PVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVT 780

Query: 781  TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSG 840
            TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSG
Sbjct: 781  TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSG 840

Query: 841  GSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAAS 900
            GSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAAS
Sbjct: 841  GSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAAS 900

Query: 901  SSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFK 960
            SSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFK
Sbjct: 901  SSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFK 960

Query: 961  FGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSA 1020
            FGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSA
Sbjct: 961  FGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSA 1020

Query: 1021 GFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKG 1080
            GFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKG
Sbjct: 1021 GFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKG 1080

Query: 1081 GFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQ 1140
            GFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQ
Sbjct: 1081 GFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQ 1140

Query: 1141 TKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSS 1200
            TKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSS
Sbjct: 1141 TKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSS 1200

Query: 1201 STPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKL 1260
            STPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKL
Sbjct: 1201 STPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKL 1260

Query: 1261 ATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFG 1320
            ATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFG
Sbjct: 1261 ATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFG 1320

Query: 1321 ANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380
            ANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ
Sbjct: 1321 ANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380

Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440
            SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ
Sbjct: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440

Query: 1441 SPAAFTVGSNGKNVFSSSGTSFSGRKIKTAVRRRK 1475
            SPAAFTVGSNGKNVFSSSGTSFSGRKIKTAVRRRK
Sbjct: 1441 SPAAFTVGSNGKNVFSSSGTSFSGRKIKTAVRRRK 1475


>gi|150418007 RAN binding protein 2 [Homo sapiens]
          Length = 3224

 Score =  184 bits (467), Expect = 5e-46
 Identities = 134/432 (31%), Positives = 186/432 (43%), Gaps = 74/432 (17%)

Query: 640  PAISSFSSSGIGFGESLKAG---------SSWQCDTCLLQNKVTDNKCIACQAAKLSPRD 690
            P  +SF        ++LK+G           W C +CL++N+    +C+ACQ    +P  
Sbjct: 1516 PTPASFKFGTSETSKTLKSGFEDMFAKKEGQWDCSSCLVRNEANATRCVACQ----NPDK 1571

Query: 691  TAKQTGIETPN--KSGKT-TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACET 747
             +  T +  P   K G + T  A  +GF   F    G WDC  CLV+N+  A KC+AC+ 
Sbjct: 1572 PSPSTSVPAPASFKFGTSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNEASATKCIACQN 1631

Query: 748  PKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNN 807
            P      K+  T + VS  A + T+ +          GF   F +  G W+CSVC V N 
Sbjct: 1632 PG-----KQNQTTSAVSTPASSETSKAPKS-------GFEGMFTKKEGQWDCSVCLVRNE 1679

Query: 808  AEDNKCVSCMSEKPGSSVPASSSSTVPVS-----LPSGGSLGLEKFKKPEGSWDCELCLV 862
            A   KC++C  + PG     +S+ + P S      P  G  G+  F K EG WDC +CLV
Sbjct: 1680 ASATKCIAC--QNPGKQNQTTSAVSTPASSETSKAPKSGFEGM--FTKKEGQWDCSVCLV 1735

Query: 863  QNKADSTKCLACE-----------------SAKPGTKSGFKGF--------------DTS 891
            +N+A +TKC+AC+                       KSGF+G                  
Sbjct: 1736 RNEASATKCIACQCPSKQNQTTAISTPASSEISKAPKSGFEGMFIRKGQWDCSVCCVQNE 1795

Query: 892  SSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFK 951
            SSS    A  + K      +  PS   T     K  D  G ++G    S   N   +  K
Sbjct: 1796 SSSLKCVACDASKPTHKPIAEAPS-AFTLGSEMKLHDSSGSQVGTGFKS---NFSEKASK 1851

Query: 952  FSKPIGDFKFG-VSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEK 1010
            F      FKFG V  E+ P  + + S N  FK     G S PVS   F+FG+S  G +EK
Sbjct: 1852 FGNTEQGFKFGHVDQENSPSFMFQGSSNTEFK-STKEGFSIPVSADGFKFGISEPGNQEK 1910

Query: 1011 KEELPKSSSAGF 1022
            K E P  +  GF
Sbjct: 1911 KSEKPLENGTGF 1922



 Score =  151 bits (381), Expect = 5e-36
 Identities = 156/583 (26%), Positives = 244/583 (41%), Gaps = 93/583 (15%)

Query: 657  KAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFG 716
            K    W C  CL++N+ T ++CIACQ  K             + NKSG + +  +   FG
Sbjct: 1414 KKEGHWDCSICLVRNEPTVSRCIACQNTK-------------SANKSGSSFVHQASFKFG 1460

Query: 717  --DKFKPVI-----------GTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVV 763
              D  KP+            G WDC  CLVQN+  + KC AC+ P+     K++L  T +
Sbjct: 1461 QGDLPKPINSDFRSVFSTKEGQWDCSACLVQNEGSSTKCAACQNPR-----KQSLPATSI 1515

Query: 764  SESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMS---EK 820
               A     +S   T  T   GF D F +  G W+CS C V N A   +CV+C +     
Sbjct: 1516 PTPASFKFGTSE--TSKTLKSGFEDMFAKKEGQWDCSSCLVRNEANATRCVACQNPDKPS 1573

Query: 821  PGSSVPASSSSTVPVS----LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACES 876
            P +SVPA +S     S     P  G  G+  F K EG WDC +CLV+N+A +TKC+AC++
Sbjct: 1574 PSTSVPAPASFKFGTSETSKAPKSGFEGM--FTKKEGQWDCSVCLVRNEASATKCIACQN 1631

Query: 877  AKPGTKS-GFKGFDTSSSSSNSAASSSFKFGVSSSSSG-------------PSQTLTSTG 922
              PG ++       T +SS  S A  S   G+ +   G              +    +  
Sbjct: 1632 --PGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNEASATKCIACQ 1689

Query: 923  NFKFGDQGGFKIGVSSDSGSINPMSEGFK--FSKPIGDFKFGV------SSESKPEEVKK 974
            N    +Q    +   + S +      GF+  F+K  G +   V      +S +K    + 
Sbjct: 1690 NPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNEASATKCIACQC 1749

Query: 975  DSKNDNFKFGLSSGLSNPVSLTP---FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINS 1031
             SK  N    +S+  S+ +S  P   F+      GQ +      ++ S+       V   
Sbjct: 1750 PSK-QNQTTAISTPASSEISKAPKSGFEGMFIRKGQWDCSVCCVQNESSSLKC---VACD 1805

Query: 1032 TPAPANTIVTSENKSSFNLGT---IETKSASVAPFTCKTSEAKK-EEMPATKGGFSFGNV 1087
               P +  + +E  S+F LG+   +   S S      K++ ++K  +   T+ GF FG+V
Sbjct: 1806 ASKPTHKPI-AEAPSAFTLGSEMKLHDSSGSQVGTGFKSNFSEKASKFGNTEQGFKFGHV 1864

Query: 1088 EPASLPSASVFVLGRTEEKQQE-----PVTSTSLVFG-KKADNEEPKCQPVFSFGNSEQT 1141
            +  + PS        TE K  +     PV++    FG  +  N+E K +     G   Q 
Sbjct: 1865 DQENSPSFMFQGSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKSEKPLENGTGFQA 1924

Query: 1142 KDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQG 1184
            +D +  K+       + S         +TF F     +T+ +G
Sbjct: 1925 QDISGQKNGRGVIFGQTS---------STFTFADLAKSTSGEG 1958



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 171/728 (23%), Positives = 250/728 (34%), Gaps = 110/728 (15%)

Query: 726  WDCDTCLVQNKPEAIKCVACETPKPGT--CVKRALTLTVVSESAETMTASSSSCTVTTGT 783
            W C++C ++N   A KCV+C+   P     V   L  TV +              VT   
Sbjct: 1356 WHCNSCSLKNASTAKKCVSCQNLNPSNKELVGPPLAETVFTPKTSPENVQDRFALVTP-- 1413

Query: 784  LGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSL 843
                    +  G W+CS+C V N    ++C++C + K   S   S SS V  +    G  
Sbjct: 1414 --------KKEGHWDCSICLVRNEPTVSRCIACQNTK---SANKSGSSFVHQASFKFGQG 1462

Query: 844  GLEK---------FKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSS 894
             L K         F   EG WDC  CLVQN+  STKC AC++ +            S  +
Sbjct: 1463 DLPKPINSDFRSVFSTKEGQWDCSACLVQNEGSSTKCAACQNPRK----------QSLPA 1512

Query: 895  SNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSK 954
            ++    +SFKFG S +S    +TL S     F  + G       D  S    +E    ++
Sbjct: 1513 TSIPTPASFKFGTSETS----KTLKSGFEDMFAKKEG-----QWDCSSCLVRNEA-NATR 1562

Query: 955  PIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEEL 1014
             +        +  KP          +FKFG S     P S   F+      G   KKE  
Sbjct: 1563 CVA-----CQNPDKPSPSTSVPAPASFKFGTSETSKAPKS--GFE------GMFTKKEGQ 1609

Query: 1015 PKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEE 1074
               S          +    A A   +  +N    N    +T SA   P + +TS+A K  
Sbjct: 1610 WDCSVC--------LVRNEASATKCIACQNPGKQN----QTTSAVSTPASSETSKAPKS- 1656

Query: 1075 MPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFS 1134
                  GF     +       SV ++       +   ++T  +  +    +      V +
Sbjct: 1657 ------GFEGMFTKKEGQWDCSVCLV-------RNEASATKCIACQNPGKQNQTTSAVST 1703

Query: 1135 FGNSEQTKDENSSKSTFSFSMTKPSEKES------EQPAKATFAFGAQTSTTADQGAAKP 1188
              +SE +K   + KS F    TK   +           A AT     Q  +  +Q  A  
Sbjct: 1704 PASSETSK---APKSGFEGMFTKKEGQWDCSVCLVRNEASATKCIACQCPSKQNQTTA-- 1758

Query: 1189 VFSFLNNSSSSSSTPATSAG-GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESS 1247
                ++  +SS  + A  +G  G+F                  S   V+  A   T +  
Sbjct: 1759 ----ISTPASSEISKAPKSGFEGMFIRKGQWDCSVCCVQNESSSLKCVACDASKPTHKPI 1814

Query: 1248 TSQSLLFSQDSKLATTSSTGTAV-TPFV--FGPGASSNNTTTSGFGFGATTTSSSAGSSF 1304
                  F+  S++    S+G+ V T F   F   AS    T  GF FG     +S    F
Sbjct: 1815 AEAPSAFTLGSEMKLHDSSGSQVGTGFKSNFSEKASKFGNTEQGFKFGHVDQENSPSFMF 1874

Query: 1305 VFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGT 1364
               +     S    F    +   G   G S+P   G     S   L       A    G 
Sbjct: 1875 QGSSNTEFKSTKEGFSIPVSAD-GFKFGISEP---GNQEKKSEKPLENGTGFQAQDISG- 1929

Query: 1365 VSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTP 1424
               + +  +FGQ  S   F       S   FQFG    NF     S +G   F +     
Sbjct: 1930 -QKNGRGVIFGQTSSTFTFADLAKSTSGEGFQFGKKDPNFK--GFSGAGEKLFSSQYGKM 1986

Query: 1425 AASAQPSG 1432
            A  A  SG
Sbjct: 1987 ANKANTSG 1994



 Score = 32.3 bits (72), Expect = 3.5
 Identities = 23/89 (25%), Positives = 39/89 (43%)

Query: 878  KPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS 937
            KP   S  K  DT S+S   +   SF FG S+  S      +++G+F FG +       +
Sbjct: 2815 KPVDLSTRKEIDTDSTSQGESKIVSFGFGSSTGLSFADLASSNSGDFAFGSKDKNFQWAN 2874

Query: 938  SDSGSINPMSEGFKFSKPIGDFKFGVSSE 966
            + +      S G + +  +G+ + G   E
Sbjct: 2875 TGAAVFGTQSVGTQSAGKVGEDEDGSDEE 2903


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score =  134 bits (336), Expect = 8e-31
 Identities = 317/1477 (21%), Positives = 541/1477 (36%), Gaps = 170/1477 (11%)

Query: 69   STDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTE--EPSTTSTASNYPDVL 126
            S++ S +   P      ++ + E SS+ T    T  P  + TE   P T++ AS  P   
Sbjct: 289  SSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVAT 348

Query: 127  TRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFS-LVKEIKDSTSQHDDDNISTTS 185
            +  S     L+ + +++  L    +  S+ P  +   S L   + + ++   +  +ST  
Sbjct: 349  SEMST----LSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTIL 404

Query: 186  GFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGN 245
              SS AS    T+  ++      + EA  S + ++ T+ ++  P+   +   ++  S   
Sbjct: 405  VASSEASTTS-TIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTP 463

Query: 246  SSILKTSQLGDSPFYPGK--TTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGV 303
             +  + S L  +P       TT   A+++   +++ + P   P         +S  +  V
Sbjct: 464  VASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPV 523

Query: 304  TSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPP 363
             SS A  +  +    S+P+  +    S  ++P  + +       T   ++     +  P 
Sbjct: 524  ASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIP------TSTPSEGSTPLTNMPV 577

Query: 364  VQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRES 423
              RL+     S  +         +T S E   +        ST  E    P     +R +
Sbjct: 578  STRLVVSSEASTTSTTPADSNTFVTTSSEASSS--------STTAEGTSMPTSTYSERGT 629

Query: 424  GFSYPNFSLPA-----ANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLP 478
              +  + S        A+ LS+        +        +S   E   M      + S P
Sbjct: 630  TITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTP 689

Query: 479  ITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEAN 538
            +TS  + T   +S E +T S +P+++S  +T     TS  ++ SP     + +  ST + 
Sbjct: 690  LTSMPVNTTLVASSEASTLSTTPVDTSTPVT-----TSTEASSSPTTADGASMPTSTPSE 744

Query: 539  VLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598
               P +     S+PV+KT   S  +STL      ++ H+TT    +C    P   EG   
Sbjct: 745  GSTPLT-----SMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCS---PTTTEGTSM 796

Query: 599  PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISS---FSSSGIGFGES 655
            P     EGS L  L S   +   + S  A   +T+PV    P  +S    SS     G S
Sbjct: 797  PISTPSEGSPL--LTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTS 854

Query: 656  LKAGSSWQCDTCLLQNKVTDNKCIACQAAKLS--PRDTAKQTGIETPNKSGKTTLSASGT 713
            +   +  +  T L    V+         + LS  P DT+      T  +S  TT  + GT
Sbjct: 855  MPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTT--SEGT 912

Query: 714  GF-----GDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAE 768
                   G+   P+    D  T +V ++   +     +T  P T    A +    +E   
Sbjct: 913  SMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTS 972

Query: 769  TMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPAS 828
              T++ S  T    +          + + E S   +S    D+      S +  S  P +
Sbjct: 973  IPTSTPSEGTTPLTSTPVSHTL---VANSEAST--LSTTPVDSNTPLTTSTEASSPPPTA 1027

Query: 829  SSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGF 888
              +++P S PS GS  L +             +V +   ST      +    T +    +
Sbjct: 1028 EGTSMPTSTPSEGSTPLTRM-------PVSTTMVASSETST----LSTTPADTSTPVTTY 1076

Query: 889  DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE 948
              +SSSS +A  +S      S  S P   LTS            ++ VSS++ +++  + 
Sbjct: 1077 SQASSSSTTADGTSMPTSTYSEGSTP---LTSV-------PVSTRLVVSSEASTLS--TT 1124

Query: 949  GFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSN---L 1005
                S P+       SS +  E     +   +   G +   S PVS T      +N    
Sbjct: 1125 PVDTSIPVTTSTEASSSPTTAEGTSIPTSPPS--EGTTPLASMPVSTTLVVSSEANTLST 1182

Query: 1006 GQEEKKEELPKSSSAGFSFGTGVI----NSTPAPANTIVTSENKSSFNLGTIETKSASVA 1061
               + K ++  S+ A     T  +     STP   +T +TS       + + E  + S +
Sbjct: 1183 TPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTS 1242

Query: 1062 PF---TCKTSEAKKEEMPATKGGFSF-------GNVEPASLPSASVFVLGRTEEKQQEPV 1111
            P    T  T+ A+    P T  G S        G+    S+P ++  V   T  +    +
Sbjct: 1243 PVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLV---TSPEASTLL 1299

Query: 1112 TSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATF 1171
            T+     G    + E    P  + G S  T       ST+S   T  +         A+ 
Sbjct: 1300 TTPVDTKGPVVTSNEVSSSPTPAEGTSMPT-------STYSEGRTPLTSIPVNTTLVASS 1352

Query: 1172 AFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTS-----------SSN 1220
            A    ++T  D          +  S+ + S+P TS G  +  S+ S           S+ 
Sbjct: 1353 AISILSTTPVDNSTP------VTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTT 1406

Query: 1221 PPVATFVFGQSSNPVSSSAFGNTAESSTS----------------------QSLLFSQ-- 1256
            P V++     S+ PV +S  G T+  +TS                      +S+  S   
Sbjct: 1407 PVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTP 1466

Query: 1257 --DSKLATTSSTGT-AVTPFVFGPGASSNNTTTSGFGFGATTTS--SSAGSSFVFGTGPS 1311
              +S+ +T S+T   + +P V     SS+ T   G     +T S  S+A +S    T   
Sbjct: 1467 VANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTV 1526

Query: 1312 AP----SASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQP--APPTFGTV 1365
            A     S S       TP    SQ +S P      S+ +ST  +  GS P  + P    +
Sbjct: 1527 ASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTST--YSEGSTPLTSLPVSTML 1584

Query: 1366 SSSSQPPVFGQQPSQSAFG-SGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTP 1424
              SS+       P  S    + +T  SSS    GSS T    +  SP  + T    S+TP
Sbjct: 1585 VVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSP--LLTSIPVSTTP 1642

Query: 1425 AASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTS 1461
             AS + S     P + +    T      +   + GTS
Sbjct: 1643 VASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTS 1679



 Score =  117 bits (294), Expect = 6e-26
 Identities = 293/1419 (20%), Positives = 499/1419 (35%), Gaps = 158/1419 (11%)

Query: 69   STDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTR 128
            S++ S V     +    +  + E SS+ T   +T  P    T  PS TST      V   
Sbjct: 2765 SSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMP----TSTPSETSTPLTSMPVNHT 2820

Query: 129  P--SLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSL-VKEIKDSTSQHDDDNISTTS 185
            P  S     L+ + +++       + +S+ P  + G  + +    + ++      +STT 
Sbjct: 2821 PVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTP 2880

Query: 186  GFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGN 245
              SS AS    T   +TS+P   S E   S + ++ T+     P+   +   ++  S   
Sbjct: 2881 VASSEASTLS-TTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVP 2939

Query: 246  SSILKTSQLGDSPFYPGK--TTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGV 303
             +  + S L  +P       TT   A+++   ++  + P   P  R+     +S  +  V
Sbjct: 2940 VAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPV 2999

Query: 304  TSS-----------TARRILQSLEKMSSPL-ADAKRIPSIVSSPLNSPLDRSGIDITDFQ 351
             SS           T+  +  S E  SSP  A+   IP    S  ++PL    +  T   
Sbjct: 3000 ASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVA 3059

Query: 352  AKREKVDSQYPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKN 411
                   S  P            + T+  V   P+         +     +   TG   +
Sbjct: 3060 IPEASTLSTTP------VDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVS 3113

Query: 412  MTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPV 471
             TP  +        +  + S P    +++           E T    S P E        
Sbjct: 3114 TTPVTSSAISTLSTTPVDTSTP----VTTSTEAHSSPTTSEGTSMPTSTPSEG------- 3162

Query: 472  LPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPI 531
                S P+T   + T    S E +T S +P+++S  +T   + TS ++        S+P 
Sbjct: 3163 ----STPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPS 3218

Query: 532  VKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPE 591
               T              SVPV+ T   S  +S L      S   +TT  ST    +PP 
Sbjct: 3219 EGMTPLT-----------SVPVSNTPVASSEASILSTTPVDSNTPLTT--STEASSSPP- 3264

Query: 592  DCEGPFRPAEILKEGS---VLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSS 648
              EG   P     EGS       + +   AS +  +++  P  TS  V T    S  SS 
Sbjct: 3265 TAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQAS--SSP 3322

Query: 649  GIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTL 708
             I  G S+   +  +  T L     +    ++ +A+ LS       T + T  ++  +  
Sbjct: 3323 PIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPT 3382

Query: 709  SASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAE 768
            +A GT       P  GT    +  V   P     V+ E     T    + TL   S  A 
Sbjct: 3383 TAEGTSIPTS-SPSEGTTPLASMPVSTTP----VVSSEVNTLSTTPVDSNTLVTTSTEAS 3437

Query: 769  TMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKP-GSSVPA 827
            +    +   ++ T T           GS   S+  +S     +   S +S  P  +S P 
Sbjct: 3438 SSPTIAEGTSLPTSTTS--------EGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPV 3489

Query: 828  SSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKG 887
            ++SS    S  +     +      EGS       + N   ST  +A   A          
Sbjct: 3490 TTSSPTNSSPTTAEVTSMPTSTAGEGSTP-----LTNMPVSTTPVASSEA---------- 3534

Query: 888  FDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMS 947
               S+ S+    S++F    S +SS P+    +T       +G   +     S +    S
Sbjct: 3535 ---STLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSS 3591

Query: 948  EGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQ 1007
            E    S P  D    V++ ++        +         S +S P+++ P       + +
Sbjct: 3592 EASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISE 3651

Query: 1008 EEKKEELPKSSSAGFSFGTGVINS------------TPAPANTIVTSENKSSFNLGTIET 1055
                  LP  +S      T V +S            TP+  +T +T+   S+  + + E 
Sbjct: 3652 AGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEG 3711

Query: 1056 KSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS 1115
             + S       T      E  ++            S+P   +  LG T      PVT   
Sbjct: 3712 STLSTPSVVTSTPVTTSTEAISSSATLD-STTMSVSMP-MEISTLGTTILVSTTPVT--- 3766

Query: 1116 LVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGA 1175
                +  ++  P    V++  +     + +SS +T   + T P    SE+    T    +
Sbjct: 3767 ----RFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLIS 3822

Query: 1176 QTSTTADQGAAKPVFSFLNNSSSSSSTP-ATSAGGGIFGSSTSSSNPPVATFVFGQSSNP 1234
              S  +   A     S L+     +STP  TS   G F  S  +    +   +  + S P
Sbjct: 3823 PISVMSPSEA-----STLSTPPGDTSTPLLTSTKAGSF--SIPAEVTTIRISITSERSTP 3875

Query: 1235 VSSSAFGNTAESSTSQSLLFSQ---DSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGF 1291
            +++     T  +S   + + S    D+    T ST TA TP +  P A++          
Sbjct: 3876 LTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTI--PVATT-------ISV 3926

Query: 1292 GATTTSSSAGSSFVFGTGPSAPSASPAF----GANQTPTFGQSQGASQPNPPGFGSISSS 1347
               T  S+ G++    + P   S +  F    GA  TP       +++ N P   S S++
Sbjct: 3927 SVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVI----TSTELNTPSTSSSSTT 3982

Query: 1348 TAL-------FPTGSQPAPPTFGTVSSSSQPP---VFGQQPSQSAFGSGTTPNSSSAFQF 1397
            T+         P  +  AP T+ T+S++   P     G   S S   + +TP++S++   
Sbjct: 3983 TSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTT 4042

Query: 1398 GSSTTNFNFTNNSPSGVFTF-----GANSSTPAASAQPS 1431
               T +   +  S     T       A+SSTP  ++  S
Sbjct: 4043 RPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASS 4081



 Score =  114 bits (286), Expect = 5e-25
 Identities = 317/1485 (21%), Positives = 532/1485 (35%), Gaps = 159/1485 (10%)

Query: 25   PIKPYQQGRQQHQGILSRVTESVKNIVPGWLQRYFNKNEDVCSCSTDTSEVPRWPENKED 84
            P   Y +GR     I  R T    + +   L      N    + ST+    P   E    
Sbjct: 1681 PTSTYTEGRTPLTSITVRTTPVASSAI-STLSTTPVDNSTPVTTSTEARSSPTTSEGTSM 1739

Query: 85   HLVYADEESSNITDGRITPEPAVSN-----------TEEPSTTST-ASNYPDVLTRPSLH 132
                  E ++ +T   ++  P +S+           T  P TTST A++ P      S+ 
Sbjct: 1740 PNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIP 1799

Query: 133  RSHLNFSML---ESPALHC-----QPSTSSAFPIGSSGFSLVKE-IKDSTSQHDDDNIST 183
             S L+  M     +P  H      + ST S  P+ S+   +    +  S +  +  +I+T
Sbjct: 1800 TSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAT 1859

Query: 184  TSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSL 243
            ++      +   I VS  T         +  +++LS   A +S           + + + 
Sbjct: 1860 STPSEGSTALTSIPVSTTTVA-------SSETNTLSTTPAVTSTPVTTYAQVSSSPTTAD 1912

Query: 244  GNSSILKTSQLGDSPFYP---GKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS 300
            G+S    T + G  P        TT   +      + L +T  + PV    +A      +
Sbjct: 1913 GSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADT--RTPVTTYSQASSSPTTA 1970

Query: 301  YGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDS- 359
             G +  T      S    S PL+    + S  S+   +P+D S    T  +       + 
Sbjct: 1971 DGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAG 2030

Query: 360  -----QYPPVQRLMTPKPVSIATNRSVYFKP---SLTP-SGEFRKTNQRIDNKCSTGYEK 410
                    P +R      + ++T   V  +    S TP   + + TN    +  +T    
Sbjct: 2031 GTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGS 2090

Query: 411  NMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRE--RTRFVASKPLEEE--E 466
            +MT     E      S P  + P A+  +S +             +  V+S P+  E   
Sbjct: 2091 SMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTS 2150

Query: 467  MEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQM-TSPSSTGSPMF 525
            M+         P+TS  + T   +S  I+T S +P+++S  +TN  +  +SP+++     
Sbjct: 2151 MQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSM 2210

Query: 526  KFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNC 585
              S+P   ST    +P S++      PV  T+E S  S+T  P+ +S     T V ++  
Sbjct: 2211 PTSTPSEGSTPFTSMPVSTM------PVV-TSEASTLSAT--PVDTS-----TPVTTSTE 2256

Query: 586  KKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF 645
              + P   EG   P   L EG+    L S   +   + +      +T+PV    P  +S 
Sbjct: 2257 ATSSPTTAEGTSIPTSTLSEGTTP--LTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTST 2314

Query: 646  SSSG---IGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702
             +S       G S+   +S + +T L +  V+     + + + LS       T + T ++
Sbjct: 2315 EASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQ 2374

Query: 703  SGKTTLSASGTG-----FGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRA 757
            +G +  +A  T      + +   P+         +V ++         +T  P T    A
Sbjct: 2375 AGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEA 2434

Query: 758  LTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCM 817
             +    +E     T+  S  T    ++        P+ S E     +S    D       
Sbjct: 2435 SSSPTTAEGTSIPTSPPSEGTTPLASMPVSTT---PVVSSEAGT--LSTTPVDTSTPMTT 2489

Query: 818  SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFK-------KPEGSWDCELCLVQNKADSTK 870
            S +  SS   +    VP+S  S GS  L            PE S    L      ++S  
Sbjct: 2490 STEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEAS---TLSTTPVDSNSPV 2546

Query: 871  CLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQG 930
              + E +   T +      TS+ S  S    S        +S  + TL++T         
Sbjct: 2547 VTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTT-------PV 2599

Query: 931  GFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFK-FGLSSGL 989
               I V++ + + +  +     S PI          S P EV     +       ++S  
Sbjct: 2600 DTSIPVTTSTETSSSPTTAKDTSMPI----------STPSEVSTSLTSILVSTMPVASSE 2649

Query: 990  SNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFN 1049
            ++ +S TP         +         SSS   + G+ +  STP   +T +T+   S+  
Sbjct: 2650 ASTLSTTPVDT------RTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTL 2703

Query: 1050 LGTIETKSASVAPF---TCKTSEAKKEEMPATKGGFSFGNVEPA--SLPSASVFVLGRTE 1104
            L   E  + S  P    T  T+ A+    P T  G S     P+  S P  S+ V     
Sbjct: 2704 LANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPV 2763

Query: 1105 EKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESE 1164
               +    ST+ V     D   P      +  +    +  +   ST S + T  +     
Sbjct: 2764 ASSEASTVSTTAV-----DTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVN 2818

Query: 1165 QPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG----------GGIFGS 1214
                A+   G  ++T  D   + PV      S+ +SS+P T+ G          G    +
Sbjct: 2819 HTPVASSEAGTLSTTPVD--TSTPV----TTSTKASSSPTTAEGIVVPISTASEGSTLLT 2872

Query: 1215 STSSSNPPVATFVFGQ-SSNPVSSSAFGNTA-ESSTSQSLLFSQDSKLATTSSTGTAVTP 1272
            S   S  PVA+      S+ PV +S    T+ E S+S +        ++T S   T +T 
Sbjct: 2873 SIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTS 2932

Query: 1273 FVFG--PGASSNNTTTSGFGFGA---TTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327
             +    P A S  +T S          TTS+ A SS     G S P ++P  G  +TP  
Sbjct: 2933 ILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTP--GERRTPLT 2990

Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGT 1387
              S        P   S +S+ +  P  +   P T  T +SSS     G     S    G+
Sbjct: 2991 SMSVSTM----PVASSEASTLSRTPADTS-TPVTTSTEASSSPTTAEGTGIPISTPSEGS 3045

Query: 1388 TPNSS-------SAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPA 1425
            TP +S        A    S+ +     +NSP    T  ++S TPA
Sbjct: 3046 TPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPA 3090



 Score =  108 bits (271), Expect = 3e-23
 Identities = 301/1506 (19%), Positives = 560/1506 (37%), Gaps = 238/1506 (15%)

Query: 102  TPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSA----FP 157
            +P P    T  P++TS+  N P  LTR  +  + +  +  E+  L   P+ +S     + 
Sbjct: 2318 SPPPTAEGTSMPTSTSSEGNTP--LTRMPVSTTMV--ASFETSTLSTTPADTSTPVTTYS 2373

Query: 158  IGSSGFSLVKEIKDSTSQHDDDN-------ISTTSGFSSRASDKDITVSKNTSLPPLWSP 210
               S  +   +    TS + + +       +ST    SS AS    T   +TS P   S 
Sbjct: 2374 QAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHS-TTPVDTSTPVTTST 2432

Query: 211  EAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNSSILKTSQLGDSPFYPGKTTYGGAA 270
            EA  S + ++ T+  +  P+   +   ++  S   ++ + +S+ G     P  T+     
Sbjct: 2433 EASSSPTTAEGTSIPTSPPSEGTTPLASMPVS---TTPVVSSEAGTLSTTPVDTSTPMTT 2489

Query: 271  AAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSPLADAKRIPS 330
            +    S        +P   +     +S  S G T      +L S+   ++P+A  +   +
Sbjct: 2490 STEASS--------SPTTAEDIVVPISTASEGST------LLTSIPVSTTPVASPEA-ST 2534

Query: 331  IVSSPL--NSPLDRSGIDITDFQAKREKVD---SQYPPVQRLMTPKPVS---IATNRSVY 382
            + ++P+  NSP+  S  +I+      E      S Y      +   PVS   +A++ +  
Sbjct: 2535 LSTTPVDSNSPVVTS-TEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEAST 2593

Query: 383  FKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGV 442
               +   +     T+    +  +T  + +M      E   S  S    ++P A+  +S +
Sbjct: 2594 LSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTL 2653

Query: 443  GGGGGKMRRERTRFV--ASKPLEEEEMEVPVLP--KISLPITSSSLPTFNFSSPEITTSS 498
                   R   T     +S P   E   +P     + S P+T+  + T   ++ E +T S
Sbjct: 2654 STTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLS 2713

Query: 499  PSPINSSQALTNKVQMTS-PSSTGSPMFKFSSPI---------------VKSTEANVLPP 542
             +P+++S  +T   + +S P++      + S+P                V S+EA+ +  
Sbjct: 2714 TTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVST 2773

Query: 543  SSIGFTFSVPVAKTAELSGSSSTLE------------------------PIISSSAHHVT 578
            +++    S+PV  + E S S +T E                        P+ SS A  ++
Sbjct: 2774 TAVDT--SIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLS 2831

Query: 579  T--------VNSTNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPT 630
            T        V ++    + P   EG   P     EGS L  L S   ++  + S  A   
Sbjct: 2832 TTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTL--LTSIPVSTTPVASSEASTL 2889

Query: 631  ATSPVVYTRPAISS---FSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLS 687
            +T+PV  + P  +S    SS     G S+   +  +  T L    V+       +A+ LS
Sbjct: 2890 STTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLS 2949

Query: 688  PRDTAKQTGIETPNKSGKTTLSASGTGF-----GDKFKPVIGTWDCDTCLVQNKPEAIKC 742
                  +T + T  ++  +  +A GT       G++  P+         +  ++   +  
Sbjct: 2950 TTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSR 3009

Query: 743  VACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSV- 801
               +T  P T        T    S+   TA  +   ++T + G       P+ +   ++ 
Sbjct: 3010 TPADTSTPVT--------TSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIP 3061

Query: 802  --CCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCEL 859
                +S    D+      S +  SS   +  +++P+S  S GS  L              
Sbjct: 3062 EASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVP---------- 3111

Query: 860  CLVQNKADSTKCLACESAKPGTKSGFKGFDTS---SSSSNSAASSSFKFGVSSSSSGPSQ 916
              V     ++  ++  S  P         DTS   ++S+ + +S +   G S  +S PS+
Sbjct: 3112 --VSTTPVTSSAISTLSTTP--------VDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSE 3161

Query: 917  TLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSS-ESKPEEVKKD 975
              T              + VSS+  +++  +     S P+       SS  ++   +   
Sbjct: 3162 GSTPLTYMPVSTM----LVVSSEDSTLS--ATPVDTSTPVTTSTEATSSTTAEGTSIPTS 3215

Query: 976  SKNDNFKFGLSSGLSNPVSLTPFQFGVSNL-------GQEEKKEELPKSSSAGFSFGTGV 1028
            + ++    G++   S PVS TP     +++                  SSS   + GT +
Sbjct: 3216 TPSE----GMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSM 3271

Query: 1029 INSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKT-----SEAKKE-------EMP 1076
              STP+  +T +TS   S+  + + ET + S  P    T     S+A           MP
Sbjct: 3272 PTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMP 3331

Query: 1077 A---TKGGFSFGNVEPASLP--SASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQP 1131
                ++G     N+  ++ P  S+    L  T      PVT+++          E    P
Sbjct: 3332 TSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTST----------EASLSP 3381

Query: 1132 VFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFS 1191
              + G S  T   +   +             +  P   T    ++ +T     +  PV S
Sbjct: 3382 TTAEGTSIPTSSPSEGTTPL-----------ASMPVSTTPVVSSEVNTL----STTPVDS 3426

Query: 1192 --FLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFG--NTAESS 1247
               +  S+ +SS+P  + G  +  S+TS  + P++  +   S+ PV+SS     +T    
Sbjct: 3427 NTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLS--IMPLSTTPVASSEASTLSTTPVD 3484

Query: 1248 TSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNN----TTTSGFGFGATTTSSSAGSS 1303
            TS  +  S  +  + T++  T++     G G++       +TT      A+T S++   S
Sbjct: 3485 TSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDS 3544

Query: 1304 FVFGTGPSAPSASPAF-------------GANQ------TPTFGQSQGASQPNPPGFGSI 1344
              F T  S  S+SPA              G++       + T+  S  AS P+ P     
Sbjct: 3545 NTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRS 3604

Query: 1345 SSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNF 1404
            +  T    + S P PP   T+  S+        PS+ +      P S+++     + T  
Sbjct: 3605 TPVTTSTQSNSTPTPPEVITLPMST--------PSEVSTPLTIMPVSTTSVTISEAGTAS 3656

Query: 1405 NFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFSG 1464
                ++ + V T    SS+P      +     P   S    T+  +   V SS G++ S 
Sbjct: 3657 TLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLST 3716

Query: 1465 RKIKTA 1470
              + T+
Sbjct: 3717 PSVVTS 3722



 Score =  105 bits (263), Expect = 2e-22
 Identities = 311/1426 (21%), Positives = 509/1426 (35%), Gaps = 200/1426 (14%)

Query: 101  ITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSS--AFPI 158
            +T  P  + T   S  ++ S  P V + P    S  + S   +     Q ST S  + P+
Sbjct: 1516 LTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPL 1575

Query: 159  GSSGFSLVKEIKD-----STSQHDDDN---ISTTSGFSSRASDKDITVSKN-------TS 203
             S   S +  +       ST+  D       ST +  S+ A    +T+S         TS
Sbjct: 1576 TSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTS 1635

Query: 204  LPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTL-SPSLGNSSILKTSQLGDSPFYPG 262
            +P   +P A    S    T   S  P    +   +  +P+ G S    T   G +P    
Sbjct: 1636 IPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPL-TS 1694

Query: 263  KTTYGGAAAAVRQSKLRNTPYQ--APVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSS 320
             T      A+   S L  TP     PV    +A+     S G +   +     +    S 
Sbjct: 1695 ITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSI 1754

Query: 321  PLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVSIATNRS 380
            P++    + S  S+   +P+D S    T  +A                T +  SI T+  
Sbjct: 1755 PVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPT-----------TAEGTSIPTST- 1802

Query: 381  VYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSS 440
                  +TP      ++  + N  S     + TP  +     +  +  +   PA      
Sbjct: 1803 --LSEGMTPLTSTPVSHTLVAN--SEASTLSTTPVDSNSPVVTSTAVSSSPTPA------ 1852

Query: 441  GVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPS 500
                       E T    S P E            S  +TS  + T   +S E  T S +
Sbjct: 1853 -----------EGTSIATSTPSEG-----------STALTSIPVSTTTVASSETNTLSTT 1890

Query: 501  PINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELS 560
            P  +S  +T   Q++S  +T        S +  ST     PP +     S+PV+ T   S
Sbjct: 1891 PAVTSTPVTTYAQVSSSPTTAD-----GSSMPTSTPREGRPPLT-----SIPVSTTTVAS 1940

Query: 561  GSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASP 620
               +TL   ++ +   VTT +  +   + P   +G   P     EGS    L S   ++ 
Sbjct: 1941 SEINTLSTTLADTRTPVTTYSQAS---SSPTTADGTSMPTPAYSEGSTP--LTSMPLSTT 1995

Query: 621  KIDSVAAQPTATSPVVYTRPAISSF---SSSGIGFGESLKAGSSWQCDTCLLQNKVTDNK 677
             + S  A   +T+PV  + PA +S    SS     G S++  +  +  T L    V+   
Sbjct: 1996 LVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTL 2055

Query: 678  CIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKP 737
             ++ +   LS      +T +     +  T  S+S T  G      I      + L+ + P
Sbjct: 2056 VVSSEGNTLSTTPVDSKTQV-----TNSTEASSSATAEGSSM--TISAPSEGSPLLTSIP 2108

Query: 738  EAIKCVACETPKPGTCVKRALTLTVVSESAETMTAS--SSSCTVTTGTL----GFGDKFK 791
             +   VA  +P+  T     L+ T V  ++  +T++  SSS   T GT      + D+ +
Sbjct: 2109 LSTTPVA--SPEAST-----LSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDR-R 2160

Query: 792  RPIGSWECSVCCVSNNA--------EDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSL 843
             P+ S   S   V+++A         D       S +  SS   S  +++P S PS GS 
Sbjct: 2161 TPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGST 2220

Query: 844  GLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSF 903
                           + +V ++A +      +++ P T S       +++   S  +S+ 
Sbjct: 2221 PFTSMPVST------MPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTL 2274

Query: 904  KFGVSSSSSGP-SQTLTSTGNFKFGD----QGGFKIGVSSDSGSINPMSEGFKFSKPIGD 958
              G +  +S P S TL +                    S+++ S  P +EG         
Sbjct: 2275 SEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTS- 2333

Query: 959  FKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSS 1018
                 S  + P      S      F  S+  + P   +      S  G      +     
Sbjct: 2334 -----SEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMP 2388

Query: 1019 SAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPAT 1078
            ++ +S G+  + S P     +V+SE  S+ +   ++T +    P T  T  +     P T
Sbjct: 2389 TSTYSEGSTPLTSVPVSTMPVVSSE-ASTHSTTPVDTST----PVTTSTEASSS---PTT 2440

Query: 1079 KGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNS 1138
              G S     P S PS     L         PV++T +V    ++       PV +    
Sbjct: 2441 AEGTSI----PTSPPSEGTTPLASM------PVSTTPVV---SSEAGTLSTTPVDT-STP 2486

Query: 1139 EQTKDENSSKSTFSFSMTKPSEKESEQ-------PAKATFAFGAQTST--TADQGAAKPV 1189
              T  E SS  T +  +  P    SE        P   T     + ST  T    +  PV
Sbjct: 2487 MTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPV 2546

Query: 1190 FSFLNNSSSSSSTPATSAGGGIFGS-STSSSNPPVATFVFGQS------SNPVSSSAFGN 1242
             +    SSS++S   TS     +   ST   + PV+T     S      + PV +S    
Sbjct: 2547 VTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVT 2606

Query: 1243 TA-ESSTSQSLLFSQDSKLATTSSTGTAVTPFVFG--PGASSNNTTTSGFGFGA---TTT 1296
            T+ E+S+S +        ++T S   T++T  +    P ASS  +T S          TT
Sbjct: 2607 TSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTT 2666

Query: 1297 SSSAGSSFVFGTGPSAPSASPAFGANQTP---------TFGQSQGASQPNPPGFGSISSS 1347
            S+   SS     G S P+++P  G   TP             S+ ++    P    + +S
Sbjct: 2667 STGTSSSPTTAEGSSMPTSTP--GERSTPLTNILVSTTLLANSEASTLSTTP----VDTS 2720

Query: 1348 TALFPTGSQPAPPTFGT-VSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSST----- 1401
            T +  +    + PT     S     P  G  P  S   S T P +SS     S+T     
Sbjct: 2721 TPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVS-TLPVASSEASTVSTTAVDTS 2779

Query: 1402 ---TNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAA 1444
               T     ++SP+        +STP+ ++ P  S   P N +P A
Sbjct: 2780 IPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTS--MPVNHTPVA 2823



 Score =  104 bits (260), Expect = 6e-22
 Identities = 298/1446 (20%), Positives = 502/1446 (34%), Gaps = 147/1446 (10%)

Query: 101  ITPEPAVSNTEEPSTTSTASNYP--DVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPI 158
            ++  P  S T+  ++T  +S  P  +V + P+      +  +   P  H   ++S A  +
Sbjct: 1180 LSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTL 1239

Query: 159  GSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASDKDITVSKNTSLPP----LWSPEAER 214
             +S       +  +TS     + +T  G S   S      +  TS+P     + SPEA  
Sbjct: 1240 STSPVDTSTPV--TTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEA-- 1295

Query: 215  SHSLSQHTATSSKKPAFNLSAFGTL-SPSLGNSSILKTSQLGDSPF--YPGKTTYGGAAA 271
              S    T   +K P    +   +  +P+ G S    T   G +P    P  TT   ++A
Sbjct: 1296 --STLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSA 1353

Query: 272  AVRQSKLRNTPYQ--APVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSPLADAKRIP 329
                S L  TP     PV    +A      S G +   +     +    S P++    + 
Sbjct: 1354 I---SILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVS 1410

Query: 330  SIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLM-----TPKPVSIATNRSVYFK 384
            S  S+   +P+D S    T  +A      ++   +         TP      +N  V   
Sbjct: 1411 SEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANS 1470

Query: 385  PSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNRE---QRESGFSYPNFSLPAA------ 435
             + T S     +N  +    ST    + TP +         S  S    S+P +      
Sbjct: 1471 EASTLSTTPVDSNSPVVT--STAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVAS 1528

Query: 436  ---NGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSP 492
               N LS+        +        +    +   M+     + S P+TS  + T    S 
Sbjct: 1529 SEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSS 1588

Query: 493  EITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVP 552
            E  T S +PI+S      K Q+T+ +   S      S +  ST     P        S+P
Sbjct: 1589 EANTLSTTPIDS------KTQVTASTEASSSTTAEGSSMTIST-----PSEGSPLLTSIP 1637

Query: 553  VAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPAEILKEGSVLDIL 612
            V+ T   S  +STL      S   V T    +   TP    EG   P     EG     L
Sbjct: 1638 VSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTP---AEGTSMPTSTYTEGRT--PL 1692

Query: 613  KSPGFASPKIDSVAAQPTATSPVVYTRPAISSF---SSSGIGFGESLKAGSSWQCDTCLL 669
             S    +  + S A    +T+PV  + P  +S    SS     G S+   +  +  T L 
Sbjct: 1693 TSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLT 1752

Query: 670  QNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTG-----FGDKFKPVIG 724
               V+    ++ +A+ LS       T + T  ++  +  +A GT        +   P+  
Sbjct: 1753 SIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTS 1812

Query: 725  TWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTL 784
            T    T +  ++   +     ++  P       +T T VS S     A  +S   +T + 
Sbjct: 1813 TPVSHTLVANSEASTLSTTPVDSNSP------VVTSTAVSSS--PTPAEGTSIATSTPSE 1864

Query: 785  GFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKP-------GSSVPASSSSTVPVSL 837
            G       P+     +    S+          ++  P        SS   +  S++P S 
Sbjct: 1865 GSTALTSIPVS----TTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTST 1920

Query: 838  PSGG-----SLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSS 892
            P  G     S+ +          +     + +        +  S+ P T  G     T +
Sbjct: 1921 PREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADG-TSMPTPA 1979

Query: 893  SSSNSAASSSFKFGVSSSSSGPSQTLTST-------------GNFKFGDQGGFKIGVSSD 939
             S  S   +S     +   S  + TL++T             G+      GG  I  S+ 
Sbjct: 1980 YSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTP 2039

Query: 940  SGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQ 999
            S    P++ G   S  +     G +  + P + K    N       ++   + ++++   
Sbjct: 2040 SERTTPLA-GMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPS 2098

Query: 1000 FGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANT-IVTSENKSSFNLGTIETKSA 1058
             G   L        +P S++   S     +++TP  +N+ ++TS   SS     I T+  
Sbjct: 2099 EGSPLL------TSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSS---SPIPTEGT 2149

Query: 1059 SVAPFTCKTSEAKKEEMPATKGGFSFGNVEPAS-LPSASVFVLGRTEEKQQEPVTS--TS 1115
            S+   T          MP +    +   +   S  P  +   +  + E +  P TS  TS
Sbjct: 2150 SMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTS 2209

Query: 1116 LVFGKKADNEEP-KCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFG 1174
            +     ++   P    PV           E S+ S      + P    +E  +  T A G
Sbjct: 2210 MPTSTPSEGSTPFTSMPV---STMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEG 2266

Query: 1175 AQTSTTADQGAAKPVFSF-------LNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFV 1227
                T+       P+ S         N+  S+ ST    +      S+ +SS PP A   
Sbjct: 2267 TSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAE-- 2324

Query: 1228 FGQSSNPVSSSAFGNTAES----STSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNN 1283
               +S P S+S+ GNT  +    ST+    F   +   T + T T VT +     A S+ 
Sbjct: 2325 --GTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTY---SQAGSSP 2379

Query: 1284 TT-------TSGFGFGATTTSSSAGSSF-VFGTGPSAPSASPAFGANQTPTFGQSQGASQ 1335
            TT       TS +  G+T  +S   S+  V  +  S  S +P      TP    ++ +S 
Sbjct: 2380 TTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPV--DTSTPVTTSTEASSS 2437

Query: 1336 PNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAF 1395
            P      SI +S     T    + P   T   SS+       P  ++    T+  +SS+ 
Sbjct: 2438 PTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSP 2497

Query: 1396 QFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVF 1455
                       T +  S + T    S+TP AS + S     P + +    T      +  
Sbjct: 2498 TTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSAT 2557

Query: 1456 SSSGTS 1461
            S+ GTS
Sbjct: 2558 SAEGTS 2563



 Score =  103 bits (258), Expect = 9e-22
 Identities = 304/1464 (20%), Positives = 514/1464 (35%), Gaps = 132/1464 (9%)

Query: 69   STDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYP--DVL 126
            S + S +   P + +  +V ++E SS+       P PA   T  P++T +    P   + 
Sbjct: 1292 SPEASTLLTTPVDTKGPVVTSNEVSSS-------PTPA-EGTSMPTSTYSEGRTPLTSIP 1343

Query: 127  TRPSLHRSHLNFSMLESPALHCQPSTSS----AFPIGSSGFSLVKEI-KDSTSQHDDDNI 181
               +L  S     +  +P  +  P T+S    + P  S G S+      + T+      +
Sbjct: 1344 VNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPV 1403

Query: 182  STTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSP 241
            STT   SS AS    T   +TS P   S EA  S + ++  +  +  P+   +   ++  
Sbjct: 1404 STTPVVSSEASTLSAT-PVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPV 1462

Query: 242  SLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSY 301
            S    +  + S L  +P           A +            +P   +  +  +S  S 
Sbjct: 1463 SNTPVANSEASTLSTTPVDSNSPVVTSTAVS-----------SSPTPAEGTSIAISTPSE 1511

Query: 302  GVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQY 361
            G T+ T+  +  +    SS +      P++ S+P+ +    S    T      +   S Y
Sbjct: 1512 GSTALTSIPV-STTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQT--STY 1568

Query: 362  PPVQRLMTPKPVS-IATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNM----TPGQ 416
                  +T  PVS +    S     S TP     +     +   ST  E +     TP +
Sbjct: 1569 SEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSE 1628

Query: 417  NREQRES-GFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKI 475
                  S   S    + P A+ LS+        +        +  P E   M      + 
Sbjct: 1629 GSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEG 1688

Query: 476  SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535
              P+TS ++ T   +S  I+T S +P+++S  +T     TS  +  SP     + +  ST
Sbjct: 1689 RTPLTSITVRTTPVASSAISTLSTTPVDNSTPVT-----TSTEARSSPTTSEGTSMPNST 1743

Query: 536  EANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEG 595
             +    P +     S+PV+ T  LS  +STL      ++  VTT        + P   EG
Sbjct: 1744 PSEGTTPLT-----SIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEAT---SSPTTAEG 1795

Query: 596  PFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISS---FSSSGIGF 652
               P   L EG  +  L S   +   + +  A   +T+PV    P ++S    SS     
Sbjct: 1796 TSIPTSTLSEG--MTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAE 1853

Query: 653  GESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASG 712
            G S+   +  +  T L    V+     + +   LS       T + T  +   +  +A G
Sbjct: 1854 GTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADG 1913

Query: 713  TGF-----GDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767
            +        +   P+       T +  ++   +     +T  P T   +A +    ++  
Sbjct: 1914 SSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGT 1973

Query: 768  ETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPA 827
               T + S  +    ++         + S E S   +S    D    +  S +  SS   
Sbjct: 1974 SMPTPAYSEGSTPLTSMPLSTTL---VVSSEAST--LSTTPVDTSTPATTSTEGSSSPTT 2028

Query: 828  SSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKG 887
            +  +++  S PS      E+     G       +V ++ ++      +S    T S    
Sbjct: 2029 AGGTSIQTSTPS------ERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNS---- 2078

Query: 888  FDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMS 947
              T +SSS +A  SS      S  S P  T                +  +    +   ++
Sbjct: 2079 --TEASSSATAEGSSMTISAPSEGS-PLLTSIPLSTTPVASPEASTLSTTPVDSNSPVIT 2135

Query: 948  EGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQ 1007
                 S PI      + + +  +     +        ++S   + +S TP          
Sbjct: 2136 STEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNS 2195

Query: 1008 EEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPF---T 1064
             E +      SS   S GT +  STP+  +T  TS   S+  + T E  + S  P    T
Sbjct: 2196 TEAR------SSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTST 2249

Query: 1065 CKTSEAKKEEMPATKGGFSF-------GNVEPASLP-------SASVFVLGRTEEKQQEP 1110
              T+  +    P T  G S        G     S+P       ++ V  L  T      P
Sbjct: 2250 PVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTP 2309

Query: 1111 VTSTSLVFGKKADNEEPKCQP--VFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAK 1168
             T TS          E    P    S GN+  T+   S+    SF  +  S   ++    
Sbjct: 2310 FT-TSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTP 2368

Query: 1169 ATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNP-----PV 1223
             T    A +S T     + P  ++   S+  +S P ++       +ST S+ P     PV
Sbjct: 2369 VTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPV 2428

Query: 1224 ATFVFGQSSN--------PVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGT-AVTPFV 1274
             T     SS         P S  + G T  +S   S      S+  T S+T     TP  
Sbjct: 2429 TTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMT 2488

Query: 1275 FGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPS-APSASP-AFGANQTPTFGQSQG 1332
                ASS+ TT        +T  +S GS+ +     S  P ASP A   + TP    S  
Sbjct: 2489 TSTEASSSPTTAEDIVVPIST--ASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPV 2546

Query: 1333 ASQPNPPGFGSISSSTAL----FPTGSQP--APPTFGTVSSSSQPPVFGQQPSQSAFGSG 1386
             +        + +  T++    +  GS P  + P      +SS+       P  ++    
Sbjct: 2547 VTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVT 2606

Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446
            T+  +SS+      T+    T +  S   T    S+ P AS++ S     P +      T
Sbjct: 2607 TSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTT 2666

Query: 1447 VGSNGKNVFSSSGTSFSGRKIKTA 1470
              S G    SSS T+  G  + T+
Sbjct: 2667 --STGT---SSSPTTAEGSSMPTS 2685



 Score =  103 bits (256), Expect = 2e-21
 Identities = 222/1055 (21%), Positives = 381/1055 (36%), Gaps = 120/1055 (11%)

Query: 458  ASKPLEEEEMEVPVLPKI--SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQ-M 514
            +S P   E   +P       S P+TS    T   +S E  T   +P+  S  +T   Q  
Sbjct: 195  SSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQAS 254

Query: 515  TSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSA 574
            +SP++   P    S+P   ST    +P        SV +  ++E S  S+T       +A
Sbjct: 255  SSPTTAEGPSLSNSAPSGGSTPLTRMP-------LSVMLVVSSEASTLSTT------PAA 301

Query: 575  HHVTTVNSTNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASP----KIDSVAAQPT 630
             ++  + ST    + P   EG   P     EGS   +  +P    P    ++ +++  P 
Sbjct: 302  TNIPVITSTEASSS-PTTAEGTSIPTSTYTEGST-PLTSTPASTMPVATSEMSTLSITPV 359

Query: 631  ATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRD 690
             TS +V T    SS  ++      S+   +  +  T L    V+     + +A+  S   
Sbjct: 360  DTSTLVTTSTEPSSLPTT--AEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIP 417

Query: 691  TAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKP 750
               +T + T +++  +  +A  T       P  G+    +  V   P A    +  +  P
Sbjct: 418  VDSKTFVTTASEASSSPTTAEDTSIATS-TPSEGSTPLTSMPVSTTPVASSEASNLSTTP 476

Query: 751  GTCVKRALTLTVVSES---AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNN 807
                 +  T T  S S   AE  +  +S+ +  +  L        P+ S E S   +S  
Sbjct: 477  VDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEAST--LSTT 534

Query: 808  AEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKAD 867
              D       S +  SS      +++P S PS GS  L                  N   
Sbjct: 535  PVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPL-----------------TNMPV 577

Query: 868  STKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFG 927
            ST+ +   S++  T S      T+ + SN+  ++S +   SS+++  +   TST +    
Sbjct: 578  STRLVV--SSEASTTS------TTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYS---- 625

Query: 928  DQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSS 987
             + G  I   S S ++   SE    S    D    V++ ++       ++  +      +
Sbjct: 626  -ERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYT 684

Query: 988  GLSNPVSLTPFQFGVSNLGQEEKKEELP------------KSSSAGFSFGTGVINSTPAP 1035
              S P++  P    +    +       P             SSS   + G  +  STP+ 
Sbjct: 685  EGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSE 744

Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEE---MPATKGGFSFG------- 1085
             +T +TS   S   L + E  + S  P    T      E    P T  G S         
Sbjct: 745  GSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEG 804

Query: 1086 ---------NVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKC-QPVFSF 1135
                     ++ P + P AS   L  T      PVT+++ V       E        +S 
Sbjct: 805  SPLLTSIPVSITPVTSPEAS--TLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSE 862

Query: 1136 GNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNN 1195
            G +  T    S+    + +++  S    +     T +  A++S T  +G + P      +
Sbjct: 863  GRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMP-----TS 917

Query: 1196 SSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFS 1255
            +    STP TS         +S +    AT V   +S PV++S    ++ ++   + + +
Sbjct: 918  TPGEGSTPLTSMPDSTTPVVSSEARTLSATPV--DTSTPVTTSTEATSSPTTAEGTSIPT 975

Query: 1256 QDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSA 1315
                  TT  T T V+  +     +S  +TT        TTS+ A S      G S P++
Sbjct: 976  STPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTS 1035

Query: 1316 SPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFG 1375
            +P+ G+  TP        +        S  +ST          P T  + +SSS     G
Sbjct: 1036 TPSEGS--TPLTRMPVSTTM-----VASSETSTLSTTPADTSTPVTTYSQASSSSTTADG 1088

Query: 1376 QQPSQSAFGSGTTPNS----SSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQ-- 1429
                 S +  G+TP +    S+     S  +  + T    S   T    +S+   +A+  
Sbjct: 1089 TSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGT 1148

Query: 1430 -----PSGSGGFPFNQSPAAFT-VGSNGKNVFSSS 1458
                 P   G  P    P + T V S+  N  S++
Sbjct: 1149 SIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTT 1183



 Score = 96.7 bits (239), Expect = 1e-19
 Identities = 224/1050 (21%), Positives = 373/1050 (35%), Gaps = 138/1050 (13%)

Query: 461  PLEEEEMEVPVLPK-ISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSS 519
            P   E+   P  P+   +P+++ S  + + +   ++T+      +  +LT KV M++P +
Sbjct: 130  PSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLT 189

Query: 520  TG-----SPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSA 574
            T      SP    S+ I KST +    P +     S+P +     S  + TL   +++  
Sbjct: 190  TSTQASSSPTTPESTTIPKSTNSEGSTPLT-----SMPASTMKVASSEAITL---LTTPV 241

Query: 575  HHVTTVNSTNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSP 634
               T V  +    + P   EGP         GS   + + P  +   + S  A   +T+P
Sbjct: 242  EISTPVTISAQASSSPTTAEGPSLSNSAPSGGST-PLTRMP-LSVMLVVSSEASTLSTTP 299

Query: 635  VVYTRPAISSFSSSG---IGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLS--PR 689
                 P I+S  +S       G S+   +  +  T L     +       + + LS  P 
Sbjct: 300  AATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPV 359

Query: 690  DTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749
            DT+      T   S  TT  A+          +  T    +  + N P +   VA     
Sbjct: 360  DTSTLVTTSTEPSSLPTTAEATSM--------LTSTLSEGSTPLTNMPVSTILVASSEAS 411

Query: 750  PGTCV---KRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSN 806
              + +    +    T    S+   TA  +S   +T + G       P+ +   +    SN
Sbjct: 412  TTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASN 471

Query: 807  NAE---DNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQ 863
             +    D+K     S +  SS P +  +++P S PS GS  L             + +  
Sbjct: 472  LSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVST------MPVAS 525

Query: 864  NKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGN 923
            ++A +      +++ P T           +SS +++SS+   G S  +S PS+  T   N
Sbjct: 526  SEASTLSTTPVDTSTPVT-----------TSSEASSSSTTPEGTSIPTSTPSEGSTPLTN 574

Query: 924  FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKF 983
                     ++ VSS++ + +        + P     F  +S     E    S       
Sbjct: 575  MPVST----RLVVSSEASTTS--------TTPADSNTFVTTSS----EASSSSTT----- 613

Query: 984  GLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSE 1043
              + G S P S   +    + +        L  SS A        +++TP  +NT VT+ 
Sbjct: 614  --AEGTSMPTST--YSERGTTITSMSVSTTLVASSEAS------TLSTTPVDSNTPVTTS 663

Query: 1044 NKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRT 1103
             +++ +  T E  S   + +T          MP          V    + S+    L  T
Sbjct: 664  TEATSSSTTAEGTSMPTSTYT--EGSTPLTSMP----------VNTTLVASSEASTLSTT 711

Query: 1104 EEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNS--EQTKDENSSKSTFSFSMTKPSEK 1161
                  PVT+++          E    P  + G S    T  E S+  T S  ++K    
Sbjct: 712  PVDTSTPVTTST----------EASSSPTTADGASMPTSTPSEGSTPLT-SMPVSKTLLT 760

Query: 1162 ESEQPAKATFAFGAQT----------STTADQGAAKPVF-----SFLNNSSSSSSTPATS 1206
             SE    +T      T          S T  +G + P+      S L  S   S TP TS
Sbjct: 761  SSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTS 820

Query: 1207 AGGGIFGSSTSSSNPPVATFVFGQSSN--------PVSSSAFGNTAESSTSQSLLFSQDS 1258
                   ++   SN PV T     SS         P S+ + G T  +S   S      S
Sbjct: 821  PEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATS 880

Query: 1259 KLATTSSTGTAV-TPFVFGPGASSNNTTTSGFGFGATTTS--SSAGSSFVFGTGPSAPSA 1315
             ++T S+T     TP      A S+ TT+ G     +T    S+  +S    T P   S 
Sbjct: 881  AISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSE 940

Query: 1316 SPAFGAN----QTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQP 1371
            +    A      TP    ++  S P      SI +ST    T    + P   T+ ++S+ 
Sbjct: 941  ARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEA 1000

Query: 1372 PVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPS 1431
                  P  S     T+  +SS       T+    T +  S   T    S+T  AS++ S
Sbjct: 1001 STLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETS 1060

Query: 1432 GSGGFPFNQSPAAFTVGSNGKNVFSSSGTS 1461
                 P + S    T      +  ++ GTS
Sbjct: 1061 TLSTTPADTSTPVTTYSQASSSSTTADGTS 1090



 Score = 92.0 bits (227), Expect = 4e-18
 Identities = 283/1296 (21%), Positives = 464/1296 (35%), Gaps = 177/1296 (13%)

Query: 89   ADEESSNITDGRI-TPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHL-NFSMLESPAL 146
            A  E+S ++   + T  P  ++ E  S+ +TA      ++ P   R+ L + S+   P  
Sbjct: 2941 AGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVA 3000

Query: 147  HCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASDKDITVSKNTSLPP 206
              + ST S  P  +S          +TS     + +T  G     S      +  TS+P 
Sbjct: 3001 SSEASTLSRTPADTS-------TPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPV 3053

Query: 207  LWSPEAERSHSLSQHTATSSKKPAFNLSAFGTL-SPSLGNSSILKTSQLGDSPF--YPGK 263
              +P A    S    T   S  P    +   +  +P+ G S  + T   G +P    P  
Sbjct: 3054 STTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVS 3113

Query: 264  TTYGGAAAAVRQSKLRNTPYQA--PVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSP 321
            TT   ++A    S L  TP     PV    +A      S G +  T+     +  + S+P
Sbjct: 3114 TTPVTSSAI---STLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTS-----TPSEGSTP 3165

Query: 322  LADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVSIATNRSV 381
            L        +V S  +S L  + +D +              PV         + A   S+
Sbjct: 3166 LTYMPVSTMLVVSSEDSTLSATPVDTST-------------PVTTSTEATSSTTAEGTSI 3212

Query: 382  YFKPSLTPS-GEFRKTNQRIDNKCSTGYEKNM---TPGQNREQRESGFSYPNFSLPAANG 437
               P+ TPS G    T+  + N      E ++   TP  +     +  +  + S P A G
Sbjct: 3213 ---PTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTS-TEASSSPPTAEG 3268

Query: 438  LSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFS----SPE 493
             S            E +  + S P+    +       +S     +S P   +S    SP 
Sbjct: 3269 TSMPTSTPS-----EGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPP 3323

Query: 494  ITTSSPSPINS----SQALTNKVQMTSP------SSTGSPMFKFSSPIVKSTEANVLPPS 543
            I   +  P ++    S  LTN    T+P      S+  +     S+P+  STEA++ P +
Sbjct: 3324 IADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTT 3383

Query: 544  SIGFTF--SVPVAKTAELSGSSSTLEPIISSSAHHVTT--------VNSTNCKKTPPEDC 593
            + G +   S P   T  L+    +  P++SS  + ++T        V ++    + P   
Sbjct: 3384 AEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIA 3443

Query: 594  EGPFRPAEILKEGSV-LDI--LKSPGFASPKIDSVAAQPTATS-PVVYTRPAISSFSSSG 649
            EG   P     EGS  L I  L +   AS +  +++  P  TS PV  + P  SS +++ 
Sbjct: 3444 EGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAE 3503

Query: 650  IGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLS 709
            +    S+   ++ +  T L    V+     + +A+ LS       T + + +++  +  +
Sbjct: 3504 V---TSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPAT 3560

Query: 710  ASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGT-CVKRALTLTVVSESAE 768
               T       P  G+    T L+ +        + E   P T  V R+  +T  ++S  
Sbjct: 3561 LQVTTMRMS-TPSEGSSSLTTMLLSST----YVTSSEASTPSTPSVDRSTPVTTSTQSNS 3615

Query: 769  TMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCV--------SNNAEDNKCVSCMSEK 820
            T T       V T  +    +   P+     S   V        S    D       S +
Sbjct: 3616 TPTPPE----VITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQ 3671

Query: 821  PGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPG 880
              SS      +T+P+  PS GS        P  +       V +   ST  L+  S    
Sbjct: 3672 VSSSPVTPEGTTMPIWTPSEGST-------PLTTMPVSTTRVTSSEGST--LSTPSVVTS 3722

Query: 881  TKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDS 940
            T         SSS++  + + S    +  S+ G +  +++T   +F +     I     S
Sbjct: 3723 TPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTS 3782

Query: 941  GSINPMSEGFKFSKPI-GDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVS-LTPF 998
             S+   SEG      + G     +S+ S+   +            L++ L +P+S ++P 
Sbjct: 3783 MSMTTASEGSSSPTTLEGTTTMPMSTTSERSTL------------LTTVLISPISVMSPS 3830

Query: 999  QFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI---VTSENKSSFNLGTIET 1055
            +    +    +    L  S+ AG SF      S PA   TI   +TSE  +      + T
Sbjct: 3831 EASTLSTPPGDTSTPLLTSTKAG-SF------SIPAEVTTIRISITSERSTPLTTLLVST 3883

Query: 1056 K------SASVAP---------FTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVL 1100
                    AS+A          FT  T  A    +P      S   +   S P  ++F+ 
Sbjct: 3884 TLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATT-ISVSVITEGSTPGTTIFI- 3941

Query: 1101 GRTEEKQQEPVTS-TSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTK-- 1157
                     PVTS T+ VF            PV +      T   +SS +T SFS TK  
Sbjct: 3942 ------PSTPVTSSTADVFPATTGAVST---PVIT-STELNTPSTSSSSTTTSFSTTKEF 3991

Query: 1158 --PSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPAT------SAGG 1209
              P+   +      T +    T  T  +G      +    S+  +ST  T      S+  
Sbjct: 3992 TTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSES 4051

Query: 1210 GIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTA 1269
                + TS + PP  TF    SS P ++SA   T       ++         TTS     
Sbjct: 4052 SRPSTITSHTIPP--TFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVT 4109

Query: 1270 VTPFVFGPGASSNNT-------TTSGFGFGATTTSS 1298
             T         SN T       TT+ FG G   T+S
Sbjct: 4110 TTAVPTNTTIKSNPTSTPTVPRTTTCFGDGCQNTAS 4145



 Score = 35.8 bits (81), Expect = 0.31
 Identities = 54/249 (21%), Positives = 90/249 (36%), Gaps = 45/249 (18%)

Query: 69   STDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYP---DV 125
            STDT+  P  P       V      S IT+G  TP   +     P T+STA  +P     
Sbjct: 3909 STDTASTPTIP-------VATTISVSVITEGS-TPGTTIFIPSTPVTSSTADVFPATTGA 3960

Query: 126  LTRPSLHRSHLNFSMLESPALHCQPSTSSAF---------PIGSSGFSLVKEIKDSTSQ- 175
            ++ P +  + LN     S +     ST+  F         P+     S       +TS+ 
Sbjct: 3961 VSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRG 4020

Query: 176  --------------HDDDNISTTSGFSSRASDKDITVSKNT----------SLPPLWSPE 211
                          H   +++T     S  S +  T++ +T          S PP  S  
Sbjct: 4021 CTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSAS 4080

Query: 212  AERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNSSILKTSQLGDSPFYPGKTTYGGAAA 271
            +   +  +  T T+  KP+   ++F T++ +   ++    S    +P  P  TT  G   
Sbjct: 4081 STTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPRTTTCFGDGC 4140

Query: 272  AVRQSKLRN 280
                S+ +N
Sbjct: 4141 QNTASRCKN 4149


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score =  127 bits (318), Expect = 1e-28
 Identities = 268/1096 (24%), Positives = 392/1096 (35%), Gaps = 187/1096 (17%)

Query: 507  ALTNKVQMTSPSSTGSPMFKFSSPIV-KSTEANVLPPSSIGFTFSVPVAK-TAELSGSSS 564
            A ++ V  +SP   G+ +   +S I+ +  ++ +L   ++      P    +A  + +++
Sbjct: 1036 AKSHLVHGSSPGVMGTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAA 1095

Query: 565  TLEPIISSSAHHVTTVNSTNCKKTPP-----EDCEGPFRPAEILKEGSVLDILKSPGFAS 619
             L   ++S A  V T+  +  K  P      E    P  P+  +         K+P    
Sbjct: 1096 ALRRQMASQAPAVNTLTESTLKNVPQVVNVQELKNNPATPSTAMGSSVPYSTAKTP---H 1152

Query: 620  PKIDSVAAQPTATSPVVYT-RPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKC 678
            P +  VAA       ++ + +P+  + +S  +  G+           T  ++  VT    
Sbjct: 1153 PVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASG-------TAKIETAVTSTPS 1205

Query: 679  IACQAAK---LSPRDTAKQTGIETPNKSGKTTLSASGT------GFGDKFKPVIGTWDCD 729
             + Q +K    SP  T    GI TP  S   T +   T         D F    G+    
Sbjct: 1206 ASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSY 1265

Query: 730  TCLVQNKPEA-IKCVACETP-KPGTCVKRALT-----LTVVSESAETMTASSSSCTVTTG 782
              + ++ P + I   +  TP +P     R +      L+  S   ET  +        + 
Sbjct: 1266 EAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSS 1325

Query: 783  TLG--FGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSG 840
              G   G      +G  + S    +N A      S    K  S VP+  + T P  L   
Sbjct: 1326 LAGETLGSFSGLRVGQADDSTK-PTNKASSTSLTSTQPTKT-SGVPSGFNFTAPPVLG-- 1381

Query: 841  GSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAAS 900
                 +  + P  S      +    A ST   A   + P T +G  G  +   +S SA  
Sbjct: 1382 -----KHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGK 1436

Query: 901  SSFKFGVSSSSS-----GPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKP 955
            +SF FG   ++S      P  T  +T          F   +SS +    PMS G    + 
Sbjct: 1437 TSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEA 1496

Query: 956  I--------GDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQ 1007
                     GD +   S+ S  EE +             S    PV   P    VSN G 
Sbjct: 1497 TSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQP---AVSNSGT 1553

Query: 1008 EEKKEELPKSSSAGFSFGTGV----------INSTPAPANTIVTSENKSSFNLGTIETKS 1057
                  L   S+      TGV           +S   P  T VT+   SS     +ET S
Sbjct: 1554 AASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETSS 1613

Query: 1058 ASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLV 1117
              +A  T            A     +FG V   S    SVF         Q P  S+S  
Sbjct: 1614 TPIASSTTSIVAPGPSAEAA-----AFGTVTSGS----SVFA--------QPPAASSSSA 1656

Query: 1118 FGKKADNEE--PKCQPVFS--FGNSEQTKDENSSKSTFSFSMTKPSEKES--EQPAKATF 1171
            F +  +N    P   PVF     ++  +     + ST S +   P    S    PA  T 
Sbjct: 1657 FNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTT 1716

Query: 1172 AFGAQTSTTADQGA--------AKPVFSFLNNSSSS--------SSTPATSAGGGIFGSS 1215
            A G    TT  Q +        A  VFSF     SS        SSTP TS  G +FG++
Sbjct: 1717 APGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTP-TSTSGSVFGAA 1775

Query: 1216 TSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKL--ATTSSTGTAVTP- 1272
            +S+S+   ++F FGQSS       FG +   +  QS  F Q   +   T+++T TA T  
Sbjct: 1776 SSTSSS--SSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSG 1833

Query: 1273 --FVFGPGASSNNT--------TTSGFGFGATTTSSSA----------GSSFVFGTG--P 1310
              F    G  S+NT        +T G  FG  ++SSS           G  F  G G  P
Sbjct: 1834 FSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKP 1893

Query: 1311 SAP--------SASPAFGANQTP------------TFG----QSQGASQPN---PPGFGS 1343
            S          SAS  FG+  T             TFG     S G  +P      G GS
Sbjct: 1894 SQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGS 1953

Query: 1344 ISSSTALFPT-------GSQP---APPTFGTVSSSSQPPVFGQQPSQSA---------FG 1384
            ++S    F +       G+ P   +PPTFG        P FG  P+ ++         FG
Sbjct: 1954 VASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFG 2013

Query: 1385 SGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGA-NSSTPAASAQPSGSGGFPFNQSPA 1443
             GT   S+  F FGSS+   +F   +     TFG+ +  T     Q SG  G  F     
Sbjct: 2014 EGTAAASAGGFGFGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSG--FGSGTG 2071

Query: 1444 AFTVGSNGKNVFSSSG 1459
             F+ GSN  +V    G
Sbjct: 2072 GFSFGSNNSSVQGFGG 2087



 Score =  124 bits (312), Expect = 5e-28
 Identities = 291/1292 (22%), Positives = 449/1292 (34%), Gaps = 255/1292 (19%)

Query: 177  DDDNISTTSGFS---------SRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSK 227
            D D +S+TS  S         +   D +  V      P + +P  + S  L  H A  +K
Sbjct: 980  DLDEVSSTSSVSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPS--LLPHAAPFAK 1037

Query: 228  KPAFNLSAFGTLSPSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPV 287
                + S+ G +  S+  S+     Q  DS     KT   GA +             A +
Sbjct: 1038 SHLVHGSSPGVMGTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAAL 1097

Query: 288  RRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDI 347
            RRQM ++  +  +  +T ST + + Q +      + + K  P+  S+ + S +       
Sbjct: 1098 RRQMASQAPAVNT--LTESTLKNVPQVVN-----VQELKNNPATPSTAMGSSV------- 1143

Query: 348  TDFQAKREKVDSQYPPVQRLMTPKPV--SIATNRSVYFK--PSLTPSGEFRKTNQRIDNK 403
                           P     TP PV   +A N++       SL PSG    + Q     
Sbjct: 1144 ---------------PYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGD 1188

Query: 404  CSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGV-----------GGGGGKMRRE 452
             ++G  K  T   +       FS P    P+  G + G+             G     +E
Sbjct: 1189 KASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKE 1248

Query: 453  RTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSP-SPINSSQALTNK 511
             ++  A       +     +P+ S P   +S        P  ++S P +P  ++ + T+ 
Sbjct: 1249 SSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGTALSTTSS 1308

Query: 512  VQMTSPSSTGSPMF----------KFSSPIVKSTEANVLPP---SSIGFTFSVPVAKTAE 558
               T PS  G  +F           FS   V   + +  P    SS   T + P   +  
Sbjct: 1309 KLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGV 1368

Query: 559  LSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFA 618
             SG + T  P++        T ++T     PP                            
Sbjct: 1369 PSGFNFTAPPVLGKHTEPPVTSSATTTSVAPP---------------------------- 1400

Query: 619  SPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGF-GESLKAGSSWQCDTCLLQNKVTDNK 677
                   AA  T+++ V  + P  S+ SS  I F G SL AG              T   
Sbjct: 1401 -------AATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGK-------------TSFS 1440

Query: 678  CIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKP 737
              + Q     P      T   TP  +   TLS     FG        T        ++  
Sbjct: 1441 FGSQQTNSTVPPSAPPPTTAATPLPTSFPTLS-----FGSLLSSAT-TPSLPMSAGRSTE 1494

Query: 738  EAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSW 797
            EA      E P        A +L    +SA+   A   +                  G+ 
Sbjct: 1495 EATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTA 1554

Query: 798  ECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVP-------VSLPSGGSLGLEKFKK 850
              S   V+ +AE     + + +    +VP +SS +VP        ++ S G + +E    
Sbjct: 1555 ASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETSST 1614

Query: 851  PEGSWDCELCLVQNKADSTKCLACES-----AKPGTKSGFKGFDTSSSSSNSAASSSFKF 905
            P  S    +      A++       S     A+P   S    F+  ++++ +A S++  F
Sbjct: 1615 PIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSATPVF 1674

Query: 906  GVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSS 965
            G  ++S+ PS          FG Q     G ++ + +  P      FS P     FG ++
Sbjct: 1675 GQVAASTAPS---------LFGQQ----TGSTASTAAATPQVSSSGFSSP----AFGTTA 1717

Query: 966  ESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFG 1025
                                           P  FG +  GQ     +   S+++ FSF 
Sbjct: 1718 -------------------------------PGVFGQTTFGQASVFGQSASSAASVFSFS 1746

Query: 1026 TGVINSTPA---PANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGF 1082
                +S PA   PA++  TS + S F   +  + S+S          +  +  P T GG 
Sbjct: 1747 QPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSF---------SFGQSSPNTGGGL 1797

Query: 1083 SFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK 1142
             FG     +   +  F  G +        T+T+   G         CQ    FG+S    
Sbjct: 1798 -FGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSF------CQ-ASGFGSSNTGS 1849

Query: 1143 DENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSS---S 1199
                + ST      + S   S         FG     + + G     FS L    S   +
Sbjct: 1850 VFGQAASTGGIVFGQQSSSSSGS------VFG-----SGNTGRGGGFFSGLGGKPSQDAA 1898

Query: 1200 SSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSK 1259
            +  P +SA GG FGS+ +S+     + +FG S     +  FG  A SS      F +   
Sbjct: 1899 NKNPFSSASGG-FGSTATSN----TSNLFGNS----GAKTFGGFASSS------FGEQKP 1943

Query: 1260 LATTSSTGTAVTPFVFGPGASSNNTTTSGFG----FGATTTSSSAGSSFVFGTGP---SA 1312
              T SS G +V    FG    S+   T GFG    FG+  T    G S  FG  P   SA
Sbjct: 1944 TGTFSSGGGSVASQGFG---FSSPNKTGGFGAAPVFGSPPT---FGGSPGFGGVPAFGSA 1997

Query: 1313 PSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPP 1372
            P+ +   G+     FG+   A+     GFGS S++T+     SQ A PTFG  S S Q  
Sbjct: 1998 PAFTSPLGSTGGKVFGEGTAAASAGGFGFGSSSNTTSFGTLASQNA-PTFG--SLSQQTS 2054

Query: 1373 VFGQQPSQ-SAFGSGTTPNSSSAFQFGSSTTN 1403
             FG Q S  S FGSGT       F FGS+ ++
Sbjct: 2055 GFGTQSSGFSGFGSGT-----GGFSFGSNNSS 2081



 Score =  104 bits (259), Expect = 7e-22
 Identities = 189/729 (25%), Positives = 271/729 (37%), Gaps = 127/729 (17%)

Query: 824  SVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKS 883
            + P++  S+ P +  SGG         PE S    +    N        A  S++P   S
Sbjct: 1242 ATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEP--AASSSRPVAPS 1299

Query: 884  GFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSI 943
            G     T+SS   +  S   +    SS +G  +TL S    + G         +  S + 
Sbjct: 1300 G-TALSTTSSKLETPPSKLGELLFPSSLAG--ETLGSFSGLRVGQADDSTKPTNKASSTS 1356

Query: 944  NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQ---F 1000
               ++  K S     F F     + P  + K ++        ++ ++ P + +      F
Sbjct: 1357 LTSTQPTKTSGVPSGFNF-----TAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVF 1411

Query: 1001 G---VSNLGQEEKKEELPKSSSAG---FSFGTGVINST---PAPANTIVTSENKSSF--- 1048
            G   V++ G          S SAG   FSFG+   NST    AP  T   +   +SF   
Sbjct: 1412 GSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTL 1471

Query: 1049 NLGTIETKSASVA-PFTC--KTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEE 1105
            + G++ + + + + P +    T EA    +P  K G S  +   ASL           EE
Sbjct: 1472 SFGSLLSSATTPSLPMSAGRSTEEATSSALPE-KPGDSEVSASAASL----------LEE 1520

Query: 1106 KQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTK--PSEKES 1163
            +Q   +             E    QP  S   +  +     + S  +   T   P  +  
Sbjct: 1521 QQSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTE 1580

Query: 1164 EQPAKATFAFGAQTSTTADQ-GAAKPVFSFLNNSSSSSST-----PATSAGGGIFGSSTS 1217
              P  ++F+   QT+ TA    +A PV    +++  +SST     P  SA    FG+ TS
Sbjct: 1581 AVPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTS 1640

Query: 1218 SSN-----------------------PPVATFVFGQ------------------------ 1230
             S+                        P AT VFGQ                        
Sbjct: 1641 GSSVFAQPPAASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAAT 1700

Query: 1231 ---SSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPF---------VFGPG 1278
               SS+  SS AFG TA     Q+  F Q S    ++S+  +V  F          FG  
Sbjct: 1701 PQVSSSGFSSPAFGTTAPGVFGQT-TFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQP 1759

Query: 1279 ASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNP 1338
            ASS  T+TSG  FGA +++SS+ SSF FG   S  +    FG +  P FGQS G  Q   
Sbjct: 1760 ASSTPTSTSGSVFGAASSTSSS-SSFSFGQS-SPNTGGGLFGQSNAPAFGQSPGFGQGGS 1817

Query: 1339 PGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFG 1398
              FG  S++T    T         G   SS+   VFGQ  S      G   +SSS   FG
Sbjct: 1818 V-FGGTSAATTTAATSGFSFCQASG-FGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFG 1875

Query: 1399 SSTTNFNFTNNSPSGVFT-FGANSSTPAASAQP--SGSGGFPFNQSPAAFTVGSNGKNVF 1455
            S  T          G F+  G   S  AA+  P  S SGGF         T  SN  N+F
Sbjct: 1876 SGNT------GRGGGFFSGLGGKPSQDAANKNPFSSASGGF-------GSTATSNTSNLF 1922

Query: 1456 SSSGTSFSG 1464
             +SG    G
Sbjct: 1923 GNSGAKTFG 1931



 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 91/405 (22%), Positives = 150/405 (37%), Gaps = 58/405 (14%)

Query: 1086 NVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDEN 1145
            +++P+ LP A+ F            V  TS+           K  P  +      TK   
Sbjct: 1023 SIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVA------TSASKIIPQGADSTMLATKTVK 1076

Query: 1146 SSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLN--NSSSSSSTP 1203
                + S  ++ P +  +    +   A  A    T  +   K V   +N     ++ +TP
Sbjct: 1077 HGAPSPSHPISAP-QAAAAAALRRQMASQAPAVNTLTESTLKNVPQVVNVQELKNNPATP 1135

Query: 1204 ATSAGGGIFGSSTSSSNP---PVA------------------TFVFGQSSNPVSSSAFGN 1242
            +T+ G  +  S+  + +P   PVA                  T   GQ S+   +S    
Sbjct: 1136 STAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASGTAK 1195

Query: 1243 TAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS 1302
               + TS      Q SK  + S +GT     +  P  SSN T       GAT ++  +  
Sbjct: 1196 IETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQ----GATPSTKESSQ 1251

Query: 1303 SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF 1362
               F +G  +  +  A   +  P+   S   + P  P   + SSS  + P+G+       
Sbjct: 1252 PDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEP---AASSSRPVAPSGT-----AL 1303

Query: 1363 GTVSS--SSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGAN 1420
             T SS   + P   G+    S+  +G T  S S  + G +  +   TN +          
Sbjct: 1304 STTSSKLETPPSKLGELLFPSSL-AGETLGSFSGLRVGQADDSTKPTNKA---------- 1352

Query: 1421 SSTPAASAQPSGSGGFP--FNQSPAAFTVGSNGKNVFSSSGTSFS 1463
            SST   S QP+ + G P  FN + A   +G + +   +SS T+ S
Sbjct: 1353 SSTSLTSTQPTKTSGVPSGFNFT-APPVLGKHTEPPVTSSATTTS 1396



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 102/424 (24%), Positives = 159/424 (37%), Gaps = 77/424 (18%)

Query: 963  VSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGF 1022
            +   S+ E    D  +D+   G+    +N V +T     +S+         L   S+ G 
Sbjct: 343  LEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEIT-----ISDEKTLPPAPVLMLLSTDGV 397

Query: 1023 SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGF 1082
                 +IN  P   + I T E  S    G  + KS    P T  +S+A  +++ A+    
Sbjct: 398  LCPFYMINQNPGVKSLIKTPERLSLE--GERQPKSPGSTPTTPTSSQAP-QKLDASAAA- 453

Query: 1083 SFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK 1142
                  PASLP +S             P+ + SL+    A         VFSFG+S    
Sbjct: 454  -----APASLPPSS----------PAAPIATFSLLPAGGAPT-------VFSFGSSSLKS 491

Query: 1143 DENSSKSTFSFSMTKPSEKESEQPAKATFAF-GAQTSTTADQGAAKPVFSFLNNSSSSSS 1201
                +    S+S    S K +  P  +TF+F     ++ A   AA PV            
Sbjct: 492  SATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPV------------ 539

Query: 1202 TPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESST---SQSLLFSQDS 1258
              A SA    FGSS          F     S PV S +  N A   +   S S +    S
Sbjct: 540  --APSAASFSFGSS---------GFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLS 588

Query: 1259 KLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPA 1318
            +  T ++T T V+       +S +    S F   ++ +  +A       T  SAP +S  
Sbjct: 589  EKFTAAATSTPVS-------SSQSAPPMSPF---SSASKPAASGPLSHPTPLSAPPSSVP 638

Query: 1319 FGAN--QTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQ 1376
              ++   +P+   +QG+S P P     +  S  + P  ++P  P     + S QP V  +
Sbjct: 639  LKSSVLPSPSGRSAQGSSSPVP---SMVQKSPRITPPAAKPGSPQ----AKSLQPAVAEK 691

Query: 1377 QPSQ 1380
            Q  Q
Sbjct: 692  QGHQ 695



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 47/174 (27%), Positives = 70/174 (40%), Gaps = 15/174 (8%)

Query: 1255 SQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPS 1314
            S  + +AT S       P VF  G+SS  ++ +  G   + +S S  S    G GPS  S
Sbjct: 462  SPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFS 521

Query: 1315 ASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF-GTVSSSSQPPV 1373
              P   A+  PT            P    ++ S A F  GS    PT   T   S   P 
Sbjct: 522  FVPPSKASLAPT------------PAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPN 569

Query: 1374 FGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAAS 1427
               +PS     S    N S  F   +++T  + + ++P    +  +++S PAAS
Sbjct: 570  IAMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPP--MSPFSSASKPAAS 621



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 71/308 (23%), Positives = 108/308 (35%), Gaps = 25/308 (8%)

Query: 1124 NEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQ 1183
            N+ P  + +         + E   KS  S   T  S   S+ P K   +  A  ++    
Sbjct: 405  NQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTS---SQAPQKLDASAAAAPASLPPS 461

Query: 1184 GAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNT 1243
              A P+ +F    +  + T  +     +  S+T +  PP        SS   SS A    
Sbjct: 462  SPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPP------SYSSGSDSSKAAPGP 515

Query: 1244 AESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSS 1303
              S+ S    F   SK +   +   A +P    P A+S +  +SGF     +T   + S+
Sbjct: 516  GPSTFS----FVPPSKASLAPTP--AASPVA--PSAASFSFGSSGFKPTLESTPVPSVSA 567

Query: 1304 FVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFG 1363
                  PS P ++ A   N +  F     A+   P    S  S+  + P  S   P   G
Sbjct: 568  PNIAMKPSFPPSTSAVKVNLSEKF---TAAATSTP--VSSSQSAPPMSPFSSASKPAASG 622

Query: 1364 TVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSST 1423
             +S    P      PS     S   P+ S     GSS+   +    SP          S 
Sbjct: 623  PLS---HPTPLSAPPSSVPLKSSVLPSPSGRSAQGSSSPVPSMVQKSPRITPPAAKPGSP 679

Query: 1424 PAASAQPS 1431
             A S QP+
Sbjct: 680  QAKSLQPA 687



 Score = 34.3 bits (77), Expect = 0.91
 Identities = 41/146 (28%), Positives = 59/146 (40%), Gaps = 17/146 (11%)

Query: 1323 QTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF---GTVSSSSQPPVFGQQPS 1379
            +TP     +G  QP  PG      ST   PT SQ AP         + +S PP     P 
Sbjct: 415  KTPERLSLEGERQPKSPG------STPTTPTSSQ-APQKLDASAAAAPASLPPSSPAAPI 467

Query: 1380 QSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFN 1439
             + F       + + F FGSS+   + T       ++ G++SS  A    PS     P +
Sbjct: 468  -ATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPS 526

Query: 1440 Q-----SPAAFTVGSNGKNV-FSSSG 1459
            +     +PAA  V  +  +  F SSG
Sbjct: 527  KASLAPTPAASPVAPSAASFSFGSSG 552


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 338/1582 (21%), Positives = 542/1582 (34%), Gaps = 292/1582 (18%)

Query: 69   STDTSEVPRWPE----NKEDHLVYADEES-------SNITDGRITPEPAVSNTEEPSTTS 117
            ST+T+ +P  P     +++    Y    S       +  T   ++ E + S+++  ST +
Sbjct: 2504 STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT 2563

Query: 118  TASNYPDVLTRPSLHR----SH-----LNFSML-----------ESPALHCQP-STSSAF 156
            TA  +PD  T P L R    SH      + ++L           ES   H  P ST +A 
Sbjct: 2564 TA--FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTAL 2621

Query: 157  PIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASDKDIT-----VSKNTSLP-PLWSP 210
              GS+  + +   ++ST+ H     + T+ F    +   I      V  +T  P    SP
Sbjct: 2622 SPGST--TALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSP 2679

Query: 211  EAERSHSLSQHTATSSKKPAFNLSAFGTLSP-SLGNSSILKTSQLGDSPFYPGKTTYGGA 269
             +  S  L   + T    PA   S   T SP S   + + +++    SP     T +  +
Sbjct: 2680 ASSTSPGLQGESTTFQTHPA---STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPAS 2736

Query: 270  AAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRI------LQSLEKMSSPLA 323
            +     S+     + +P           + + G   ST  RI      + +L   ++   
Sbjct: 2737 STTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPG 2796

Query: 324  DAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVSIAT------ 377
             ++   +  SSP +     S   +T      E   S+  P     T  P S  T      
Sbjct: 2797 LSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEE 2856

Query: 378  NRSVYFK-PSLTPSGEF-RKTNQRIDNKCSTGY-------------EKNMTPGQNREQRE 422
            + +VY   P  T +  F R T   +  +  T +             E + T G   E   
Sbjct: 2857 STTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEEST- 2915

Query: 423  SGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSS 482
               ++P        GL + +      +  E T F +S       +  P     S  +  S
Sbjct: 2916 ---AFPGSPASTQTGLPATLTTAD--LGEESTTFPSSSGSTGTTLS-PARSTTSGLVGES 2969

Query: 483  SLPTFNFSSPEITTSSPSPIN---SSQALTNKVQMTSPSSTGSPMFKFSSPIVK------ 533
            +    + SS E TT   SP     S ++ T      SP +T SP    SS + +      
Sbjct: 2970 TPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSH 3029

Query: 534  ----STEANVLPPSSIGFTFS-VPVAKTAELSGSSSTLEP---IISSSAHHVTTVNSTNC 585
                ST     P S+     S  P A  +    + +TL P     SS     TT +S+  
Sbjct: 3030 SQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSS-- 3087

Query: 586  KKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF 645
                P D E    P + +  G V         ++P   S  +  T  +P           
Sbjct: 3088 ----PGDTETTLLPDDTITSGLV-------EASTPTHSSTGSLHTTLTPA---------- 3126

Query: 646  SSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIET-----P 700
            SS+  G  E      SW   +                     P  TA    + T     P
Sbjct: 3127 SSTSAGLQEESTTFQSWPSSS---------------DTTPSPPGTTAAPVEVSTTYHSRP 3171

Query: 701  NKSGKTTLSASGTGFGDKFKPVI---GTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRA 757
            + +  T  SAS T  G   +            T L   +      V   T  P   +   
Sbjct: 3172 SSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSP---ISSG 3228

Query: 758  LTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCM 817
             T T     + T    S   T    +    D    P  +    V   S  +      +  
Sbjct: 3229 STETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHT 3288

Query: 818  SEKPGS--------------SVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQ 863
            +  PGS              S P S+ +T+     +  SLG E      G    E  L+ 
Sbjct: 3289 TAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLP 3348

Query: 864  NKADSTKCL-ACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTG 922
            +   ++  L A       T S       + S++    S++F+   +S  + P+   T++ 
Sbjct: 3349 DNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSA 3408

Query: 923  NFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFK 982
              +           S  S S  P +     S  +G  +   +  S P      +   +  
Sbjct: 3409 FVELST-------TSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVAT---ATTPSPA 3458

Query: 983  FGLSSGL--------SNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPA 1034
               +SGL        S+P S     F  S+      +E     SS      T  I+S P+
Sbjct: 3459 RSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSST-----THTISSAPS 3513

Query: 1035 PANTIV---TSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPAS 1091
              + +V   TS + S  +  T     +S      + S A      AT      G +   +
Sbjct: 3514 TTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDAT------GTIVLPA 3567

Query: 1092 LPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTF 1151
              + SV +LG   E    P++S S+         E    P      S  T   +   +TF
Sbjct: 3568 RSTTSV-LLG---ESTTSPISSGSM---------ETTALP-----GSTTTPGLSEKSTTF 3609

Query: 1152 SFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGI 1211
              S   P+   S  PA  T +  ++ STT+    ++P       S+ +++ P ++   G+
Sbjct: 3610 HSSPRSPATTLS--PASTTSSGVSEESTTSH---SRP------GSTHTTAFPDSTTTPGL 3658

Query: 1212 FGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSST----G 1267
               ST+S + P +T     +  P S++  G++ ES+TS S   S D+ L+  S+T    G
Sbjct: 3659 SRHSTTSHSSPGST---DTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFG 3715

Query: 1268 TAVTPFVFGPGAS-----SNNTTTSGFGFGATTTSSSAGS-----SFVFGTGPSAPSASP 1317
               T F   PG++      ++TT+SG    +T   SS GS     S    T P     S 
Sbjct: 3716 QESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGEST 3775

Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSI-------------SSSTALFPTGS--------- 1355
            AF  +   T       + P+PP   +              S+ T  FP  S         
Sbjct: 3776 AFQTHPASTH------TTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKS 3829

Query: 1356 ---QPAPPTFGTVSSSSQPPVFGQQPSQSAF------------GSGTTPNSSSAFQFGSS 1400
                 +P   GT  SS+     G+  S ++             GS TTP  S A     S
Sbjct: 3830 TIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYS 3889

Query: 1401 TTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT---VGSNGKNVFSS 1457
            +     T  SP+ + + G    +  + +QP   G      SPA+ T   +      V+SS
Sbjct: 3890 SPRSPTTTLSPASMTSLGVGEESTTSRSQP---GSTHSTVSPASTTTPGLSEESTTVYSS 3946

Query: 1458 S----GTSFSGRKIKTAVRRRK 1475
            S     T+   R   T+VRR +
Sbjct: 3947 SPGSTETTVFPRSTTTSVRREE 3968



 Score = 97.4 bits (241), Expect = 9e-20
 Identities = 312/1492 (20%), Positives = 506/1492 (33%), Gaps = 229/1492 (15%)

Query: 94   SNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHR----SHLNFSMLESPALHC- 148
            ++ T   ++ E   S +   ST +TA  +PD  T P L R    SH +    ++  L   
Sbjct: 983  ASTTSSGVSEESTTSRSRPGSTHTTA--FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAS 1040

Query: 149  -------QPSTSSAFPIGSSGFSL-------VKEIKDSTSQHDDDNISTTSGFSSRASDK 194
                   Q ST+S    GS+  +L       +   ++ST+ H +   + T+ F    +  
Sbjct: 1041 TTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSS 1100

Query: 195  DITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS----PSLGNSSILK 250
             I  +         SP    S + S       +  AF      T +    PS   + + +
Sbjct: 1101 GIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEE 1160

Query: 251  TSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARR 310
            ++    SP     T +  ++     S+     + +P           + + G   ST  R
Sbjct: 1161 STTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR 1220

Query: 311  I------LQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPV 364
            I      + +L   ++    ++   +  SSP +     S   +T      E   S+  P 
Sbjct: 1221 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 1280

Query: 365  QRLMTPKPVSIAT------NRSVY-----------FKPSLTPSGEFRKTNQRIDNKCSTG 407
                T  P S  T      + +VY           F  S T S    +         ST 
Sbjct: 1281 STHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTH 1340

Query: 408  YEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEM 467
                          E   ++P        GL + +      +  E T F +S      ++
Sbjct: 1341 TTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTAD--LGEESTTFPSSSGSTGTKL 1398

Query: 468  EVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPIN---SSQALTNKVQMTSPSSTGSPM 524
              P     S  +  S+    + SS E TT   SP     S ++ T      SP +T SP 
Sbjct: 1399 S-PARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPA 1457

Query: 525  FKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELS-------GSSSTLEPIISSSAHHV 577
               SS + + +  +   P S   T       T++LS        S  + E  +S  +   
Sbjct: 1458 TTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGS--- 1514

Query: 578  TTVNSTNCKKT----PPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATS 633
            TT +S   + T     P D E    P + +  G V         ++P   S  +  T  +
Sbjct: 1515 TTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLV-------EASTPTHSSTGSLHTTLT 1567

Query: 634  PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAK 693
            P           SS+  G  E      SW   +                     P  TA 
Sbjct: 1568 PA----------SSTSAGLQEESTTFQSWPSSS---------------DTTPSPPGTTAA 1602

Query: 694  QTGIET-----PNKSGKTTLSASGTGFGDKFKPVI---GTWDCDTCLVQNKPEAIKCVAC 745
               + T     P+ +  T  SAS T  G   +            T L   +      V  
Sbjct: 1603 PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE 1662

Query: 746  ETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVS 805
             T  P   +    T T     + T    S   T    +    D    P  +    V   S
Sbjct: 1663 PTTSP---ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEES 1719

Query: 806  NNAEDNKCVSCMSEKPGS--------------SVPASSSSTVPVSLPSGGSLGLEK--FK 849
              +      +  +  PGS              S P S+ +T+     +  SLG E   F 
Sbjct: 1720 TTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFH 1779

Query: 850  KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSS 909
               GS +  L L  N   S    A       T S       + S++    S++F+   SS
Sbjct: 1780 SSPGSTETTL-LPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSS 1838

Query: 910  SSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKP 969
              + P+   T++   +           S  S S  P +     S  +G  +   +  S P
Sbjct: 1839 KDTMPAPPTTTSAFVELST-------TSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSP 1891

Query: 970  EEVKKDSKNDNFKFGLSSGL--------SNPVSLTPFQFGVSNLGQEEKKEELPKSSSAG 1021
                  +   +     +SGL        S+P S     F  S+      +E     SS  
Sbjct: 1892 VAT---ATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSST- 1947

Query: 1022 FSFGTGVINSTPAPANTIV---TSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPAT 1078
                T  I+S P+  + +V   TS + S  +  T     +S      + S A      AT
Sbjct: 1948 ----THTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDAT 2003

Query: 1079 KGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNS 1138
                  G +   +  + SV +LG   E    P++S S+         E    P      S
Sbjct: 2004 ------GTIVLPARSTTSV-LLG---ESTTSPISSGSM---------ETTALP-----GS 2039

Query: 1139 EQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSS 1198
              T   +   +TF  S   P+   S  PA  T +  ++ STT+    ++P       S+ 
Sbjct: 2040 TTTPGLSEKSTTFHSSPRSPATTLS--PASTTSSGVSEESTTSH---SRP------GSTH 2088

Query: 1199 SSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDS 1258
            +++ P ++   G+   ST+S + P +T     +  P S++  G + ES+TS S   S D+
Sbjct: 2089 TTAFPDSTTTPGLSRHSTTSHSSPGST---DTTLLPASTTTSGPSQESTTSHSSPGSTDT 2145

Query: 1259 KLATTSST----GTAVTPFVFGPGAS-----SNNTTTSGFGFGATTTSSSAGS-----SF 1304
             L+  S+T    G   T F   PG++      ++TT+SG    +T   SS GS     S 
Sbjct: 2146 ALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSP 2205

Query: 1305 VFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSI---SSSTALFPTGSQPA--- 1358
               T P     S AF  +   T       + P+PP   +     S+T     GS P    
Sbjct: 2206 ASSTSPGLQGESTAFQTHPASTH------TTPSPPSTATAPVEESTTYHRSPGSTPTTHF 2259

Query: 1359 PPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFG 1418
            P +  T   S +  +F   P      SGTTP+S+ +   G   +  +  +   + + T  
Sbjct: 2260 PASSTTSGHSEKSTIFHSSPD----ASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP 2315

Query: 1419 ANSSTPAASAQPSGSGGFPFNQ----SPAAFT---VGSNGKNVFSSSGTSFS 1463
             +++TP  S   +     P +     SPA+ T   VG       S  G++ S
Sbjct: 2316 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHS 2367



 Score = 94.4 bits (233), Expect = 7e-19
 Identities = 340/1570 (21%), Positives = 534/1570 (34%), Gaps = 285/1570 (18%)

Query: 69   STDTSEVPRWPENK---EDHLVYADEESSNITDGRITPEPAVSNTEEPSTT------STA 119
            ST+T+  PR P      E+   +    +S  T    T +   S   E ST       ST 
Sbjct: 2393 STETTVFPRTPTTSVRGEEPTTFHSRPASTHTT-LFTEDSTTSGLTEESTAFPGSPASTQ 2451

Query: 120  SNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDD 179
            +  P  LT   L      F     P+      T+ + P  S+   LV E   S       
Sbjct: 2452 TGLPATLTTADLGEESTTF-----PSSSGSTGTTLS-PARSTTSGLVGESTPSRLSPSST 2505

Query: 180  NISTTSGFSSRAS--DKDITVSKNTSLPPLW-SPEAERSHSLSQHTATSSKKP-AFNLSA 235
              +T  G  +  S  +K  T   +   P    SP    S  +S+ ++TS  +P + + +A
Sbjct: 2506 ETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTA 2565

Query: 236  F--GTLSPSLGNSSILKTSQLG--DSPFYPGKTTYGGAAAAVRQSKLRNTPYQAP--VRR 289
            F   T +P L   S    S  G  D+   P  TT  G       S+   T + +P     
Sbjct: 2566 FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGP------SQESTTSHSSPGSTDT 2619

Query: 290  QMKAKQLSAQSYGVTSST-------ARRILQSLEKMSSPLADAK-RIPSIVSSPLNSPLD 341
             +     +A S+G  S+T           L      SS + +A  R+ S   SP  +   
Sbjct: 2620 ALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSP 2679

Query: 342  RSGIDITDFQAKREKVDSQYPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRID 401
             S    T    + E    Q  P     TP P S AT           P  E    ++   
Sbjct: 2680 ASS---TSPGLQGESTTFQTHPASTHTTPSPPSTAT----------APVEESTTYHRSPG 2726

Query: 402  NKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKP 461
            +  +T +  + T   + E+     S P+ S    +   S   G G            +  
Sbjct: 2727 STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES---------TTSR 2777

Query: 462  LEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTG 521
            +     E+  LP  +     S   T  +SSP   T++ SP + +     +   TS S  G
Sbjct: 2778 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 2837

Query: 522  SPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVN 581
                        ST + V P S+           T  LS  S+T+      S        
Sbjct: 2838 ------------STHSTVSPAST----------TTPGLSEESTTVYSSSPGSTETTVFPR 2875

Query: 582  STNCKKTPPEDCEGPFRPAE----ILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVY 637
            ST       E      RPA     +  E S    L     A P        P +T   + 
Sbjct: 2876 STTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFP------GSPASTQTGL- 2928

Query: 638  TRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIA-CQAAKLSPRDTAKQTG 696
              PA  + +++ +G   +    SS    T L   + T +  +     ++LSP  T   T 
Sbjct: 2929 --PA--TLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTT- 2983

Query: 697  IETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKR 756
               P      +LS   T F    +    T    T       E     +    +PG+    
Sbjct: 2984 --LPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEE---SSTSHSQPGSTHTT 3038

Query: 757  AL-TLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE-----D 810
            A    T  S  ++  TAS SS   T  TL  G      +G    +      + E     D
Sbjct: 3039 AFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPD 3098

Query: 811  NKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTK 870
            +   S + E    +  ++ S    ++  S  S GL++      SW        + +D+T 
Sbjct: 3099 DTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSW-------PSSSDTTP 3151

Query: 871  CLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQG 930
                 +A P   S       SS+ +   ++SS   G S  S+    +  +TG   F  + 
Sbjct: 3152 SPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRS 3211

Query: 931  GFKIGV--------------------SSDSGSINPMSEGFKFS--------KPIGDFKFG 962
               + V                    S+ +  ++  S  F  S         P      G
Sbjct: 3212 ATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSG 3271

Query: 963  VSSESKPEEVKKDSKNDNFKFGL--------------SSGLSNPVSLTPFQFGVSNLGQE 1008
            VS ES     +  S +     G               SS  S   +L+P     S+LG E
Sbjct: 3272 VSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPE 3331

Query: 1009 E----------KKEELPKSSSAG--FSFGTGVINSTPAPANTI-----VTSENKSSFNLG 1051
                       +   LP +++A       T V +ST +P  T+      T + +S+    
Sbjct: 3332 STTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQS 3391

Query: 1052 TIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLP----SASVFVLGRTEEK- 1106
               +K  + AP    T+ +   E+  T  G       P+S P    SAS   LGR+EE  
Sbjct: 3392 WPNSKDTTPAP---PTTTSAFVELSTTSHG------SPSSTPTTHFSASSTTLGRSEEST 3442

Query: 1107 --QQEPV-----------TSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDE--------- 1144
                 PV           T++ LV      +  P       F  S+ T            
Sbjct: 3443 TVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHS 3502

Query: 1145 ------NSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSS 1198
                  +S+ ST S  + +P+   S   + AT  F   +STT+ +           +++ 
Sbjct: 3503 STTHTISSAPSTTSALVEEPTSYHSSPGSTATTHF-PDSSTTSGRSEESTASHSSQDATG 3561

Query: 1199 SSSTPATSAGGGIFGSSTSS---------SNPPVATFVFGQSS----------------N 1233
            +   PA S    + G ST+S         +  P +T   G S                 +
Sbjct: 3562 TIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLS 3621

Query: 1234 PVSSSAFGNTAESSTSQSLLFSQD-------------SKLATTS-----STGTAVTPFVF 1275
            P S+++ G + ES+TS S   S               S+ +TTS     ST T + P   
Sbjct: 3622 PASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAST 3681

Query: 1276 GPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQ 1335
                SS  +TTS    G+T T+ S GS+     G  + +   + G+  T  F  S  +S 
Sbjct: 3682 TTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSS- 3740

Query: 1336 PNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGT----TPNS 1391
                  G + +ST +    S  +P T  + +SS+ P + G+  +     + T    +P S
Sbjct: 3741 ------GIVEASTRVH--SSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPS 3792

Query: 1392 SSAFQFGSSTTNFNFTNNSPSGVF-----TFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446
            ++      STT      ++P+  F     T G +  +    + P  SG  P   S A  T
Sbjct: 3793 TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTP---SSAHST 3849

Query: 1447 VGSNGKNVFS 1456
                G++  S
Sbjct: 3850 TSGRGESTTS 3859



 Score = 91.3 bits (225), Expect = 6e-18
 Identities = 307/1469 (20%), Positives = 511/1469 (34%), Gaps = 211/1469 (14%)

Query: 80   ENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFS 139
            E+    L  +  E++ +     TP    S +E+ +T  T+   PD    P+   S  +  
Sbjct: 2968 ESTPSRLSPSSTETTTLPGSPTTP----SLSEKSTTFYTSPRSPDATLSPATTTS--SGV 3021

Query: 140  MLESPALHCQPSTS--SAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSG----------- 186
              ES   H QP ++  +AFP  ++   L +E   S S       + + G           
Sbjct: 3022 SEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQS 3081

Query: 187  --FSSRASDKDITVSKNTSLPPLWSPEAERSHSL--SQHTATSSKKPAFNLSAFGTLSPS 242
              F S   D + T+  + ++       +  +HS   S HT  +   PA + SA G    S
Sbjct: 3082 TTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT---PASSTSA-GLQEES 3137

Query: 243  LGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYG 302
                S   +S    SP  PG T      +    S+  +TP                  + 
Sbjct: 3138 TTFQSWPSSSDTTPSP--PGTTAAPVEVSTTYHSRPSSTP---------------TTHFS 3180

Query: 303  VTSSTARRILQSLEKMSSPLADAKRI-------PSIVSSPLNSPLDRSGIDITDFQAKRE 355
             +S+T  R  +S    SSP A    +         +V  P  SP+     + T       
Sbjct: 3181 ASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTT 3240

Query: 356  KVDSQYPPVQRLMTPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMT-P 414
                         +P+  S  T  S     S   S E   ++ R  +  +T +  + T P
Sbjct: 3241 TAGLSEKSTTFYSSPR--SPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP 3298

Query: 415  GQNREQRES-------------GFSYPNFSLPAANGLSSGVGGGGGKMRRERTR----FV 457
            G ++E   S             G +  +   P +    SG G     +  + T       
Sbjct: 3299 GVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLE 3358

Query: 458  ASKPLEEE--EMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMT 515
            AS P+          + P  S      S    ++ + + TT +P    S+    +     
Sbjct: 3359 ASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHG 3418

Query: 516  SPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAH 575
            SPSST +  F  SS  +  +E +    SS       PVA     S + ST   ++  S  
Sbjct: 3419 SPSSTPTTHFSASSTTLGRSEESTTVHSS-------PVATATTPSPARSTTSGLVEESTT 3471

Query: 576  HVTTVNSTNCKKTPPEDC-EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSP 634
            + ++  ST     P  D   G    +      +   I  +P   S  ++   +  ++   
Sbjct: 3472 YHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGS 3531

Query: 635  VVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQ 694
               T    SS +S   G  E   A  S Q  T  +         +    +  SP  +   
Sbjct: 3532 TATTHFPDSSTTS---GRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSM 3588

Query: 695  TGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCV 754
                 P  +    LS   T F                   + P +          P T +
Sbjct: 3589 ETTALPGSTTTPGLSEKSTTF------------------HSSPRS----------PATTL 3620

Query: 755  KRALTLTV-VSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKC 813
              A T +  VSE + T    S S   +T T  F D    P  S   +    S  + D   
Sbjct: 3621 SPASTTSSGVSEESTT----SHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL 3676

Query: 814  VSCMSEKPGSSVPA----SSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869
            +   +   GSS  +    SSS +   +L  G +  L        S+  E     +   ST
Sbjct: 3677 LPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTAL--------SFGQESTTFHSSPGST 3728

Query: 870  KCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQ 929
                              F  S++SS    +S+    V SS+  P  TL+   +   G Q
Sbjct: 3729 HTTL--------------FPDSTTSSGIVEAST---RVHSSTGSPRTTLSPASSTSPGLQ 3771

Query: 930  G---GFKIGVSSD-------SGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979
            G    F+   +S        S +  P+ E   + +  G      S+ +        +   
Sbjct: 3772 GESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPG------STPTTHFPASSTTSGH 3825

Query: 980  NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039
            + K  +     +    TP     +  G+ E       S+++  S G+  I + P    T 
Sbjct: 3826 SEKSTIFHSSPDASGTTPSSAHSTTSGRGE-------STTSRISPGSTEITTLPGSTTTP 3878

Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKG--GFSFGNVEPASLPSASV 1097
              SE  ++F   +  + + +++P +  TS    EE   ++   G +   V PAS  +   
Sbjct: 3879 GLSEASTTF-YSSPRSPTTTLSPASM-TSLGVGEESTTSRSQPGSTHSTVSPASTTTP-- 3934

Query: 1098 FVLGRTEEK----QQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSF 1153
               G +EE        P ++ + VF +       + +P         T     ++ + + 
Sbjct: 3935 ---GLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTS 3991

Query: 1154 SMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFG 1213
             +T+ S      PA       A T TTAD G     F   + S+ +  +PA S   G+ G
Sbjct: 3992 GLTEESTAFPGSPASTQTGLPA-TLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVG 4050

Query: 1214 SSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKL--ATTSSTGTA-- 1269
             ST S   P +T       +P + S    + +S+T  +   S D+ L  ATT+S+G +  
Sbjct: 4051 ESTPSRLSPSSTETTTLPGSPTTPSL---SEKSTTFYTSPRSPDATLSPATTTSSGVSEE 4107

Query: 1270 -----VTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQT 1324
                   P      A  ++TTTSG     TT+ SS GS+      P + +AS      Q+
Sbjct: 4108 SSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEA-TLSPGSTTASSL--GQQS 4164

Query: 1325 PTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAF- 1383
             TF  S G ++       +I+S      T +  +  +  T  + +     G Q   + F 
Sbjct: 4165 TTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQ 4224

Query: 1384 ----GSGTTPN--SSSAFQFGSSTTNFNFTNNSPSGVF-----TFGANSSTPAASAQPSG 1432
                 S TTP+  S++A     STT  +  +++P+  F     T G +  +    + P  
Sbjct: 4225 SWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGA 4284

Query: 1433 SGGFPF-NQSPAAFTVGSNGKNVFSSSGT 1460
            +G   F  +S  +  VG    +  SS  T
Sbjct: 4285 TGTALFPTRSATSVLVGEPTTSPISSGST 4313



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 313/1496 (20%), Positives = 500/1496 (33%), Gaps = 191/1496 (12%)

Query: 69   STDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTR 128
            S D       P      ++  D   S I+ G +       +T +P  +  ++ +      
Sbjct: 586  SPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRS 645

Query: 129  PSLHRSHLNFSML------ESPALHCQPSTS--SAFPIGSSGFSLVKEIKDSTSQHDDDN 180
            P    +HL  SM       ES   H +P ++  +AFP  ++   L +E   ST+ H    
Sbjct: 646  PDT--THLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQE---STASH---- 696

Query: 181  ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS 240
                    S     D T+S  ++      PE    HS    T T+      N +A G L 
Sbjct: 697  --------SSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPD--NTTASGLLE 746

Query: 241  PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS 300
             S+   S  ++     SP   G TT  G +              AP        + S  S
Sbjct: 747  ASMPVHSSTRSPHTTLSP--AGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTS 804

Query: 301  YGVTSS------TARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKR 354
            +G  SS      +AR     L + S+    +      +  P +      G + T   +  
Sbjct: 805  HGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSST 864

Query: 355  EKVDSQYPPVQRLMTPKPVSI----ATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEK 410
                S  P     +  +P S      +  + +F  S T SG   ++     ++ +TG   
Sbjct: 865  THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATG--- 921

Query: 411  NMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVP 470
                                 LPA +  S  +G               + P+    ME  
Sbjct: 922  ------------------TIVLPARSTTSVLLGES------------TTSPISSGSMETT 951

Query: 471  VLP-KISLPITSSSLPTFNFS--SPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKF 527
             LP   + P  S    TF+ S  SP  T S  S  +S  +  +    + P ST +  F  
Sbjct: 952  ALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPD 1011

Query: 528  SSPIVKSTEANVLPPSSIGFTFS--VPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNC 585
            S+     +  +    SS G T +  +P + T       ST     S S     +  ST  
Sbjct: 1012 STTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTA 1071

Query: 586  KKTPPEDCEGPFRPAEILKEGSVLDILKSPGF--ASPKIDSVAAQP-TATSPVVYTRPAI 642
                 E       P          D   S G   AS ++ S    P T  SP   T P +
Sbjct: 1072 LSFGQESTTFHSNPGS-THTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL 1130

Query: 643  SSFSSSGIGFGESL-KAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPN 701
               S++      S     S     T  ++   T ++          P  +       T  
Sbjct: 1131 QGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASST------TSG 1184

Query: 702  KSGKTTL-----SASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKR 756
             S K+T+      ASGT          G  +  T  +      I  +   T  PG  +  
Sbjct: 1185 HSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPG--LSE 1242

Query: 757  ALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSC 816
            A T    S  + T T S +S T    +LG G++          +   VS  +     +S 
Sbjct: 1243 ASTTFYSSPRSPTTTLSPASMT----SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSE 1298

Query: 817  MSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACES 876
             S    SS   S+ +TV     +    G E              L    + ++      +
Sbjct: 1299 ESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEEST 1358

Query: 877  AKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPS-QTLTSTGNFKFGDQGGFKIG 935
            A PG+ +  +    ++ ++      S  F  SS S+G       ST +   G+    ++ 
Sbjct: 1359 AFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLS 1418

Query: 936  VSS----------DSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGL 985
             SS           + S++  S  F  S    D     ++ +    V ++S   + + G 
Sbjct: 1419 PSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS-SGVSEESSTSHSQPGS 1477

Query: 986  SSGLSNPVSLTPFQFG----VSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVT 1041
            +   + P S T          S+  Q   +  L   S+   S G        +P +T  T
Sbjct: 1478 THTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETT 1537

Query: 1042 SENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPA--TKGGFSFGNVEPASLPSASVFV 1099
                 +   G +E  +    P    T        PA  T  G    +    S PS+S   
Sbjct: 1538 LLPDDTITSGLVEAST----PTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSS--- 1590

Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSF-------GNSEQTKDENSS----- 1147
                +     P T+ + V      +  P   P   F       G SE++   +SS     
Sbjct: 1591 ----DTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATG 1646

Query: 1148 ------KSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSS 1201
                  +S  S  + +P+       +  T A    T TTA        F     S  ++ 
Sbjct: 1647 TALFPTRSATSVLVGEPTTSPISSGSTETTALPGST-TTAGLSEKSTTFYSSPRSPDTTL 1705

Query: 1202 TPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLA 1261
            +PA++   G+   ST+S + P +T     ++ P S++  G + ES+ S S   S D+ L+
Sbjct: 1706 SPASTTSSGVSEESTTSHSRPGSTHT---TAFPGSTTMPGVSQESTASHSSPGSTDTTLS 1762

Query: 1262 ----TTSSTGTAVTPFVFGPGASS-----NNTTTSGFGFGATTTSSSAGS---------- 1302
                T SS G   T F   PG++      +NTT SG    +T   SS GS          
Sbjct: 1763 PGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGS 1822

Query: 1303 ------SFVFGTGPSAPSASPAFGANQTPTFGQ----SQGASQPNPPGFGSISSST---A 1349
                  S  F + PS+    PA     T  F +    S G+    P    S SS+T   +
Sbjct: 1823 TTRQGESTTFQSWPSSKDTMPA-PPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRS 1881

Query: 1350 LFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNN 1409
               T    +P    T  S ++    G     +A+ S  +P S+    F  S+T    +  
Sbjct: 1882 EESTTVHSSPVATATTPSPARSTTSGLVEESTAYHS--SPGSTQTMHFPESSTASGRSEE 1939

Query: 1410 SPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFSGR 1465
            S +       +S+T   S+ PS +       +    + GS     F  S T+ SGR
Sbjct: 1940 SRT-----SHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTT-SGR 1989



 Score = 87.8 bits (216), Expect = 7e-17
 Identities = 317/1454 (21%), Positives = 499/1454 (34%), Gaps = 252/1454 (17%)

Query: 113  PSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDS 172
            PS++ T  + P     P          +  S   H +PS++      +S  +L +  ++S
Sbjct: 1587 PSSSDTTPSPPGTTAAP----------VEVSTTYHSRPSSTPTTHFSASSTTLGRS-EES 1635

Query: 173  TSQHDDDNISTTSGFSSRASDKDITVSKNTSLPPLWS--------PEAERSHSLSQHTAT 224
            T+ H     + T+ F +R++   +     TS  P+ S        P +  +  LS+ + T
Sbjct: 1636 TTVHSSPGATGTALFPTRSATSVLVGEPTTS--PISSGSTETTALPGSTTTAGLSEKSTT 1693

Query: 225  ---SSKKPAFNLSAFGTLSPSLGNSSILKTSQLGDS--PFYPGKTTYGGAAAAVRQSKLR 279
               S + P   LS   T S  +   S    S+ G +    +PG TT  G    V Q    
Sbjct: 1694 FYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG----VSQESTA 1749

Query: 280  NTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLE--------------KMSSPLADA 325
            +          +     +A S G  S+T      S E              + S+P+  +
Sbjct: 1750 SHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSS 1809

Query: 326  KRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVSIATNRSVYFKP 385
               P    SP  S   R G + T FQ+     D+   P     T     +  + + +  P
Sbjct: 1810 TGSPHTTLSPAGSTT-RQG-ESTTFQSWPSSKDTMPAPP----TTTSAFVELSTTSHGSP 1863

Query: 386  SLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGG 445
            S TP+  F  ++               T G++ E      S    S P A   +      
Sbjct: 1864 SSTPTTHFSASST--------------TLGRSEE------STTVHSSPVATATTPSPARS 1903

Query: 446  GGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSS 505
                  E +    S P   + M     P+ S     S     + SS   T SSP    S+
Sbjct: 1904 TTSGLVEESTAYHSSPGSTQTMH---FPESSTASGRSEESRTSHSSTTHTISSPPSTTSA 1960

Query: 506  QALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSV--PVAKTAELSGSS 563
                     +SP ST +  F  SS     +E +    SS   T ++  P   T  +    
Sbjct: 1961 LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGE 2020

Query: 564  STLEPIISSSAHHVTTVNSTNCKKTPPEDC---EGPFRPAEILKEGSVLDILKSPGFASP 620
            ST  PI S S        ST       +       P  PA  L   S      S G +  
Sbjct: 2021 STTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTT----SSGVSEE 2076

Query: 621  KIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIA 680
               S  ++P +T    +      S ++ G+    +    S    DT LL    T +    
Sbjct: 2077 STTS-HSRPGSTHTTAFP----DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG--- 2128

Query: 681  CQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAI 740
               ++ S    +     +T    G TT  + G                ++    + P + 
Sbjct: 2129 --PSQESTTSHSSPGSTDTALSPGSTTALSFGQ---------------ESTTFHSSPGST 2171

Query: 741  KCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECS 800
                       + +  A T    S  +   T S +S T + G  G    F+    S   +
Sbjct: 2172 HTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASST-SPGLQGESTAFQTHPASTHTT 2230

Query: 801  VCCVSNNAEDNKCVSCMSEKPGSS----VPASSSSTVPVSLPSGGSLGLEKF-KKPEGSW 855
                S      +  +     PGS+     PASS++       SG S     F   P+ S 
Sbjct: 2231 PSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTT-------SGHSEKSTIFHSSPDASG 2283

Query: 856  DCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPS 915
                    + A ST     ES       G     T   S+ +   S       SS   P+
Sbjct: 2284 T-----TPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPT 2338

Query: 916  QTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975
             TL+       G      +G  S +    P S     S P      G+S ES        
Sbjct: 2339 TTLSPASMTSLG------VGEESTTSRSQPGSTHSTVS-PASTTTPGLSEESTTV----- 2386

Query: 976  SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035
                   +  S G S   ++ P     S  G+E                     +S PA 
Sbjct: 2387 -------YSSSPG-STETTVFPRTPTTSVRGEEPT-----------------TFHSRPAS 2421

Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095
             +T + +E+ ++  L T E+ +   +P + +T       +PAT      G  E  + PS+
Sbjct: 2422 THTTLFTEDSTTSGL-TEESTAFPGSPASTQTG------LPATLTTADLGE-ESTTFPSS 2473

Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNE-EPKCQPVFSFGNSEQTKDENSSKSTFSFS 1154
            S    G T        ++TS + G+   +   P      +   S  T   +   +TF  S
Sbjct: 2474 S----GSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTS 2529

Query: 1155 MTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGS 1214
               P    S  PA  T +  ++ S+T+    ++P       S+ +++ P ++   G+   
Sbjct: 2530 PRSPDATLS--PATTTSSGVSEESSTSH---SQP------GSTHTTAFPDSTTTPGLSRH 2578

Query: 1215 STSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSST----GTAV 1270
            ST+S + P +T     +  P S++  G + ES+TS S   S D+ L+  S+T    G   
Sbjct: 2579 STTSHSSPGST---DTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQES 2635

Query: 1271 TPFVFGPGASS-----NNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTP 1325
            T F   PG++      ++TT+SG    +T   SS GS     T   A S SP      T 
Sbjct: 2636 TTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRT--TLSPASSTSPGLQGEST- 2692

Query: 1326 TFGQSQGASQ---PNPPGFGSI-------------SSSTALFPTGS------------QP 1357
            TF Q+  AS    P+PP   +              S+ T  FP  S              
Sbjct: 2693 TF-QTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHS 2751

Query: 1358 APPTFGTVSSSSQPPVFGQQPSQSAF------------GSGTTPNSSSAFQFGSSTTNFN 1405
            +P   GT  SS+     G+  S ++             GS TTP  S A     S+    
Sbjct: 2752 SPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSP 2811

Query: 1406 FTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT---VGSNGKNVFSSS---- 1458
             T  SP+ + + G    +  + +QP   G      SPA+ T   +      V+SSS    
Sbjct: 2812 TTTLSPASMTSLGVGEESTTSRSQP---GSTHSTVSPASTTTPGLSEESTTVYSSSPGST 2868

Query: 1459 GTSFSGRKIKTAVR 1472
             T+   R   T+VR
Sbjct: 2869 ETTVFPRSTTTSVR 2882



 Score = 87.4 bits (215), Expect = 9e-17
 Identities = 319/1497 (21%), Positives = 505/1497 (33%), Gaps = 242/1497 (16%)

Query: 93   SSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPST 152
            S+  T   +  EP   ++   ST +T  ++PD  T     RS       ES A H     
Sbjct: 3510 SAPSTTSALVEEPTSYHSSPGSTATT--HFPDSSTTSG--RSE------ESTASHSSQDA 3559

Query: 153  SSAFPIGSSGFSLVKEIKDSTSQHDDDNISTT----SGFSSRASDKDITVSKNTSLPPLW 208
            +    + +   + V   + +TS     ++ TT    S  +   S+K  T   +   P   
Sbjct: 3560 TGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATT 3619

Query: 209  -SPEAERSHSLSQHTATSSKKP-AFNLSAF--GTLSPSLGNSSILKTSQLG--DSPFYPG 262
             SP +  S  +S+ + TS  +P + + +AF   T +P L   S    S  G  D+   P 
Sbjct: 3620 LSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 3679

Query: 263  KTTYGGAA----AAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLEKM 318
             TT  G++     +   S   +T         +   Q S   +    ST   +       
Sbjct: 3680 STTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTS 3739

Query: 319  SSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVSIATN 378
            S  +  + R+ S   SP  +    S    T    + E    Q  P     TP P S AT 
Sbjct: 3740 SGIVEASTRVHSSTGSPRTTLSPASS---TSPGLQGESTAFQTHPASTHTTPSPPSTAT- 3795

Query: 379  RSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGL 438
                      P  E    ++   +  +T +  + T   + E+     S P+ S    +  
Sbjct: 3796 ---------APVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSA 3846

Query: 439  SSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSS 498
             S   G G            +  +     E+  LP  +     S   T  +SSP   T++
Sbjct: 3847 HSTTSGRGES---------TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTT 3897

Query: 499  PSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAE 558
             SP + +     +   TS S  G            ST + V P S+           T  
Sbjct: 3898 LSPASMTSLGVGEESTTSRSQPG------------STHSTVSPAST----------TTPG 3935

Query: 559  LSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPAE----ILKEGSVLDILKS 614
            LS  S+T+      S        ST       E      RPA     +  E S    L  
Sbjct: 3936 LSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTE 3995

Query: 615  PGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVT 674
               A P        P +T   +   PA  + +++ +G   +    SS    T L   + T
Sbjct: 3996 ESTAFP------GSPASTQTGL---PA--TLTTADLGEESTTFPSSSGSTGTKLSPARST 4044

Query: 675  DNKCIA-CQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLV 733
             +  +     ++LSP  T   T    P      +LS   T F    +    T    T   
Sbjct: 4045 TSGLVGESTPSRLSPSSTETTT---LPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 4101

Query: 734  QNKPEAIKCVACETPKPGTCVKRAL-TLTVVSESAETMTASSSSCTVTTGTLGFGDKFKR 792
                E     +    +PG+    A    T  S  ++  T S SS   T  TL  G     
Sbjct: 4102 SGVSEE---SSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTAS 4158

Query: 793  PIGSWECSVCCVSNNAE-----DNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEK 847
             +G    +      + E     D+   S + E    +  ++ S    ++  S  S GL++
Sbjct: 4159 SLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQE 4218

Query: 848  FKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGV 907
                  SW        + +D+T      +A P   S       SS+ +   ++SS   G 
Sbjct: 4219 ESTTFQSW-------PSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGR 4271

Query: 908  SSSSSGPSQTLTSTGNFKFGDQGGFKIGV--------------------SSDSGSINPMS 947
            S  S+    +  +TG   F  +    + V                    S+ +  ++  S
Sbjct: 4272 SEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKS 4331

Query: 948  EGFKFS--------KPIGDFKFGVSSESK--------------PEEVKKDSKNDNFKFGL 985
              F  S         P      GVS ES               P        +       
Sbjct: 4332 TTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASH 4391

Query: 986  SSGLSNPVSLTPFQFGVSNLGQEE----------KKEELPKSSSAG--FSFGTGVINSTP 1033
            SS  S   +L+P     S+LG E           +   LP +++A       T V +ST 
Sbjct: 4392 SSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTG 4451

Query: 1034 APANTI-----VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVE 1088
            +P  T+      T + +S+       +K  + AP    T+ +   E+  T  G       
Sbjct: 4452 SPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAP---PTTTSAFVELSTTSHG------S 4502

Query: 1089 PASLP----SASVFVLGRTEEK---QQEPV-----------TSTSLVFGKKADNEEPKCQ 1130
            P+S P    SAS   LGR+EE       PV           T++ LV      +  P   
Sbjct: 4503 PSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGST 4562

Query: 1131 PVFSFGNSEQTKDE---------------NSSKSTFSFSMTKPSEKESEQPAKATFAFGA 1175
                F  S  T                  +S+ ST S  + +P+   S   + AT  F  
Sbjct: 4563 QTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHF-P 4621

Query: 1176 QTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTS---SSNPPVATFVFGQSS 1232
             +STT+ +           +++ +   PA S    + G ST+   SS     T + G ++
Sbjct: 4622 DSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTT 4681

Query: 1233 NP----------VSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSN 1282
             P           S S+   T  S++S +L  S++S    +S   TA TP       S  
Sbjct: 4682 TPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTP-------SPA 4734

Query: 1283 NTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFG-ANQTPTFGQSQGASQPNPPGF 1341
             +TTSG    +T   SS GS+         P +S A G + ++ T   S   +  +PP  
Sbjct: 4735 RSTTSGLVEESTAYHSSPGSTQTM----HFPESSTASGRSEESRTSHSSTTHTISSPP-- 4788

Query: 1342 GSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGS-----GTTPNSSSAFQ 1396
             S +S+    PT    +P +  T          G+    +A  S     G TP  +    
Sbjct: 4789 -STTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTT 4847

Query: 1397 FGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQP----SGSGGFPFNQSPAAFTVGS 1449
             G    +  F  +  S   T  + ++TP  SA+     S S       SPA+ T  S
Sbjct: 4848 SGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSS 4904



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 305/1451 (21%), Positives = 492/1451 (33%), Gaps = 199/1451 (13%)

Query: 78   WPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSH-- 135
            +P +    +   + ++S IT        ++  T  P +T+TA       T  S  RS   
Sbjct: 239  FPSHSATSVFVGEPKTSPITSA------SMETTALPGSTTTAGLSEKSTTFYSSPRSPDR 292

Query: 136  -LNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASDK 194
             L+ +   S  +  + +TS + P    G +      DST+       ST S   S     
Sbjct: 293  TLSPARTTSSGVSEKSTTSHSRP----GPTHTIAFPDSTTMPGVSQESTAS--HSIPGST 346

Query: 195  DITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNSSILKTSQL 254
            D T+S  T+ P    PE+   HS   +T T+             L  +   S +L+ S  
Sbjct: 347  DTTLSPGTTTPSSLGPESTTFHSSPGYTKTTR------------LPDNTTTSGLLEASTP 394

Query: 255  GDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQS 314
              S      TT   +++   + +   T +Q+       +K  S    G TS         
Sbjct: 395  VHSSTGSPHTTLSPSSSTTHEGE--PTTFQS----WPSSKDTSPAPSGTTS--------- 439

Query: 315  LEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVS 374
                    A  K   +  SSP ++P        T      E       PV    TP P  
Sbjct: 440  --------AFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPAR 491

Query: 375  IATN----------------RSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNR 418
             AT+                ++++F  S T SG    + +      ST + K+ TP    
Sbjct: 492  SATSGHVEESTAYHRSPGSTQTMHFPESSTTSGH---SEESATFHGSTTHTKSSTPSTTA 548

Query: 419  EQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLP 478
                + +     S    +   S    G    R E ++   S P   + M   VLP  S P
Sbjct: 549  ALAHTSYHSSLGSTETTHFRDSSTISG----RSEESKASHSSP---DAMATTVLPAGSTP 601

Query: 479  ------ITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIV 532
                   T S + + +  +  +  S+  P  S ++ T      SP +T  P    SS + 
Sbjct: 602  SVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVS 661

Query: 533  KSTEANVLPPSSIGFTFSVPVAKT-----AELSGSSSTLEPIISSSAHHVTTVNSTNCKK 587
            + +  +   P S   T + P + T      E + S S+  P  ++ +   TT +S   + 
Sbjct: 662  EESTTSHSRPGST-HTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEY 720

Query: 588  TP----PEDCEGPFRPAEILKEG------SVLDILKSPGFASPKIDSVAAQPTATSPVVY 637
            T     P   E    P      G       V    +SP        S   Q  +T+   +
Sbjct: 721  TTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSW 780

Query: 638  -----TRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTA 692
                 TRPA  + +S+ +    +     S    T +     T            SP  T 
Sbjct: 781  PSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQ 840

Query: 693  KQTGIETPNKSGK---TTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749
                 E+   SG+   +T S S T         I +    T  +  +P +          
Sbjct: 841  TMHFPESDTTSGRGEESTTSHSST------THTISSAPSTTSALVEEPTSYH------SS 888

Query: 750  PG-TCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNA 808
            PG T        +  S  +E  TAS SS    TGT+    +    +   E +   +S+ +
Sbjct: 889  PGSTATTHFPDSSTTSGRSEESTASHSS-QDATGTIVLPARSTTSVLLGESTTSPISSGS 947

Query: 809  EDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADS 868
             +   +   +  PG     S  ST   S P   +  L            E    +++  S
Sbjct: 948  METTALPGSTTTPG----LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGS 1003

Query: 869  TKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGN----- 923
            T   A   +   T  G     T+S SS  +  ++     S+++SGPSQ  T++ +     
Sbjct: 1004 THTTAFPDST--TTPGLSRHSTTSHSSPGSTDTTL-LPASTTTSGPSQESTTSHSSSGST 1060

Query: 924  ---FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDN 980
                  G       G  S +   NP S       P      G+   S        S    
Sbjct: 1061 DTALSPGSTTALSFGQESTTFHSNPGSTHTTLF-PDSTTSSGIVEASTRVHSSTGSPRTT 1119

Query: 981  FKFGLSSGLSNPVSLTPFQ---FGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPAN 1037
                 S+        T FQ                  P   S  +    G   +T  PA+
Sbjct: 1120 LSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPAS 1179

Query: 1038 TIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLP---- 1093
            +  +  ++ S    +    S +       T+  + E   +T    S G+ E  +LP    
Sbjct: 1180 STTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGE---STTSRISPGSTEITTLPGSTT 1236

Query: 1094 -------SASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDEN- 1145
                   S + +   R+      P + TSL  G+++     +     S  +   T     
Sbjct: 1237 TPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL 1296

Query: 1146 SSKSTFSFSMTKPSEKESEQP-AKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPA 1204
            S +ST  +S ++ S + +  P +  T   G + +T   + A+     F  +S++S  T  
Sbjct: 1297 SEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEE 1356

Query: 1205 TSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTS 1264
            ++A  G   S+ +     + T   G+ S    SS+     + S ++S          TTS
Sbjct: 1357 STAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARS----------TTS 1406

Query: 1265 STGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSA--SPAFGAN 1322
                  TP    P  SS  TTT     G+ TT S +  S  F T P +P A  SPA   +
Sbjct: 1407 GLVGESTPSRLSP--SSTETTTLP---GSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 1461

Query: 1323 QTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSA 1382
               +   S   SQP        S+ T  FP  +        T S  SQ P      SQ +
Sbjct: 1462 SGVSEESSTSHSQPG-------STHTTAFPDST--------TTSDLSQEPTTSHS-SQGS 1505

Query: 1383 FGSGTTPNSSSAFQFGSSTTNFNF------TNNSPSGVFTFG-ANSSTPAASAQPSGSGG 1435
              +  +P S++A   G  +T F+       T   P    T G   +STP  S+    +G 
Sbjct: 1506 TEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSS----TGS 1561

Query: 1436 FPFNQSPAAFT 1446
                 +PA+ T
Sbjct: 1562 LHTTLTPASST 1572



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 326/1556 (20%), Positives = 520/1556 (33%), Gaps = 272/1556 (17%)

Query: 94   SNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHR----SHLNFSMLESPALHC- 148
            ++ T   ++ E   S++   ST +TA  +PD  T P L R    SH +    ++  L   
Sbjct: 3623 ASTTSSGVSEESTTSHSRPGSTHTTA--FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAS 3680

Query: 149  -------QPSTSSAFPIGSSGFSL-------VKEIKDSTSQHDDDNISTTSGFSSRASDK 194
                   Q ST+S    GS+  +L       +   ++ST+ H     + T+ F    +  
Sbjct: 3681 TTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSS 3740

Query: 195  DITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS----PSLGNSSILK 250
             I  +         SP    S + S       +  AF      T +    PS   + + +
Sbjct: 3741 GIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEE 3800

Query: 251  TSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARR 310
            ++    SP     T +  ++     S+     + +P           + + G   ST  R
Sbjct: 3801 STTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR 3860

Query: 311  I------LQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPV 364
            I      + +L   ++    ++   +  SSP +     S   +T      E   S+  P 
Sbjct: 3861 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 3920

Query: 365  QRLMTPKPVSIAT------NRSVYFK-PSLTPSGEF-RKTNQRIDNKCSTGY-------- 408
                T  P S  T      + +VY   P  T +  F R T   +  +  T +        
Sbjct: 3921 STHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTH 3980

Query: 409  -----EKNMTPGQNREQRESGFSYPNFSLPAANGLS----------------SGVGGGGG 447
                 E + T G   E      ++P        GL                 S  G  G 
Sbjct: 3981 TTLFTEDSTTSGLTEEST----AFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT 4036

Query: 448  KMRRERTRFVA----SKP--LEEEEMEVPVLP-KISLPITSSSLPTFNFS--SPEITTSS 498
            K+   R+        S P  L     E   LP   + P  S    TF  S  SP+ T S 
Sbjct: 4037 KLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSP 4096

Query: 499  PSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSV--PVAKT 556
             +  +S  +  +    + P ST +  F  S+     ++      SS G T +   P + T
Sbjct: 4097 ATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTT 4156

Query: 557  AELSGSSSTLEPIISSSAHHVTTVNSTNC-------KKTPPEDCEGPFR----PAE---- 601
            A   G  ST     SS     TT+   +          TP     G       PA     
Sbjct: 4157 ASSLGQQSTT--FHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTST 4214

Query: 602  -ILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPA---ISSFSSSGIGFGESLK 657
             + +E +      S    +P   S  A P   S   ++RP+    + FS+S    G S +
Sbjct: 4215 GLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEE 4274

Query: 658  A----GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGT 713
            +     S     T L   +   +  +       SP  +        P  +    LS   T
Sbjct: 4275 STTVHSSPGATGTALFPTRSATSVLVG--EPTTSPISSGSTETTALPGSTTTAGLSEKST 4332

Query: 714  GFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRAL-TLTVVSESAETMTA 772
             F    +    T    +       E          +PG+    A  + T +   ++  TA
Sbjct: 4333 TFYSSPRSPDTTLSPASTTSSGVSEES---TTSHSRPGSMHTTAFPSSTTMPGVSQESTA 4389

Query: 773  SSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE-----DNKCVSCMSEKPGSSVPA 827
            S SS   T  TL  G      +G    +      + E     DN   S + E   +S P 
Sbjct: 4390 SHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLE---ASTPV 4446

Query: 828  SSSSTVP-VSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886
             SS+  P  +L   GS   +       SW        N  D+T       A P T S F 
Sbjct: 4447 HSSTGSPHTTLSPAGSTTRQGESTTFQSWP-------NSKDTTP------APPTTTSAFV 4493

Query: 887  GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946
               T+S  S S+  ++  F  SS++ G S+  T+  +             S+ SG +   
Sbjct: 4494 ELSTTSHGSPSSTPTTH-FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEES 4552

Query: 947  SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006
            +             F  S+ +     +  + + +    +SS  S   +L        +  
Sbjct: 4553 TTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSP 4612

Query: 1007 QEEKKEELPKSS--SAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFT 1064
                    P SS  S      T   +S  A    ++ + + +S  LG      ++ +P +
Sbjct: 4613 GSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLG-----ESTTSPIS 4667

Query: 1065 CKTSEAKKEEMPATKGGFSFGNV----EPASLP----SASVFVLGRTEEK---QQEPV-- 1111
              + E        T  G S  +      P+S P    SAS   LGR+EE       PV  
Sbjct: 4668 SGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVAT 4727

Query: 1112 ---------TSTSLVFGKKADNEEPKCQPVFSF-------GNSEQTKDENSSK------- 1148
                     T++ LV    A +  P       F       G SE+++  +SS        
Sbjct: 4728 ATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSP 4787

Query: 1149 -STFSFSMTKPSEKESEQPAKATFAFGAQTSTTA------------DQGAAKPVFSFLNN 1195
             ST S  + +P+   S   + AT  F   ++T+             D     P+ +    
Sbjct: 4788 PSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTT 4847

Query: 1196 S--------------------SSSSSTPATSAGGGIFGSS-------------TSSSNPP 1222
            S                    +S+++TP  SA   I  SS             TSSS   
Sbjct: 4848 SGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISG 4907

Query: 1223 VATFVFGQSSN------PVSSSAFGNTAESSTSQSLLFSQDSKLA----TTSSTGTAVTP 1272
              T ++ Q+ +      P S++  G + ES+T  S   S ++ L+    TTSS     T 
Sbjct: 4908 EPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTT 4967

Query: 1273 FVFGPGA-----SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327
                PG+     S  +TT  G    +TT  SS GS           + + AF  + T + 
Sbjct: 4968 PHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGS-----------TETTAFSHSNTMSI 5016

Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGT 1387
               Q    P+ PGF    + T L        P T  T     +   F    S  A G+  
Sbjct: 5017 HSQQSTPFPDSPGF----THTVL--------PATLTTTDIGQESTAF--HSSSDATGTTP 5062

Query: 1388 TPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPA 1443
             P  S+A       T F + + SP+    F A+SST   + + +      F+ SP+
Sbjct: 5063 LPARSTASDLVGEPTTF-YISPSPTYTTLFPASSSTSGLTEEST-----TFHTSPS 5112



 Score = 77.4 bits (189), Expect = 9e-14
 Identities = 311/1442 (21%), Positives = 494/1442 (34%), Gaps = 208/1442 (14%)

Query: 113  PSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDS 172
            PS++ T  + P     P          +  S   H +PS++      +S  +L +  ++S
Sbjct: 3144 PSSSDTTPSPPGTTAAP----------VEVSTTYHSRPSSTPTTHFSASSTTLGRS-EES 3192

Query: 173  TSQHDDDNISTTSGFSSRASDKDITVSKNTSLPPLWS--------PEAERSHSLSQHTAT 224
            T+ H     + T+ F +R++   +     TS  P+ S        P +  +  LS+ + T
Sbjct: 3193 TTVHSSPGATGTALFPTRSATSVLVGEPTTS--PISSGSTETTALPGSTTTAGLSEKSTT 3250

Query: 225  ---SSKKPAFNLSAFGTLSPSLGNSSILKTSQLGDS--PFYPGKTTYGGAAAAVRQSKLR 279
               S + P   LS   T S  +   S    S+ G +    +PG TT  G    V Q    
Sbjct: 3251 FYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG----VSQESTA 3306

Query: 280  NTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLE--------------KMSSPLADA 325
            +          +     +A S G  S+T      S E              + S+P+  +
Sbjct: 3307 SHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSS 3366

Query: 326  KRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVSIATNRSVYFKP 385
               P    SP  S   R G + T FQ+     D+         TP P    T  S + + 
Sbjct: 3367 TGSPHTTLSPAGSTT-RQG-ESTTFQSWPNSKDT---------TPAP---PTTTSAFVEL 3412

Query: 386  SLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGG 445
            S T  G    T        +T +  + T     E+  +  S P  +    +   S   G 
Sbjct: 3413 STTSHGSPSSTP-------TTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSG- 3464

Query: 446  GGKMRRERTRFVASKPLEEEEMEVPVLPKIS----LPITSSSLPTFNFSSPEITTSSPSP 501
               +  E T + +S P   + M  P     S       TS S  T   SS   TTS+   
Sbjct: 3465 ---LVEESTTYHSS-PGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVE 3520

Query: 502  INSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSV--PVAKTAEL 559
              +S         +SP ST +  F  SS     +E +    SS   T ++  P   T  +
Sbjct: 3521 EPTSYH-------SSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSV 3573

Query: 560  SGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDC---EGPFRPAEILKEGSV----LDIL 612
                ST  PI S S        ST       +       P  PA  L   S     +   
Sbjct: 3574 LLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEE 3633

Query: 613  KSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNK 672
             +   + P      A P +T+    +R + +S SS G               DT LL   
Sbjct: 3634 STTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG-------------STDTTLLPAS 3680

Query: 673  VTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCL 732
             T +      +++ S    +     +T    G TT  + G                ++  
Sbjct: 3681 TTTSG-----SSQESTTSHSSSGSTDTALSPGSTTALSFGQ---------------ESTT 3720

Query: 733  VQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKR 792
              + P +            + +  A T    S  +   T S +S T + G  G    F+ 
Sbjct: 3721 FHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASST-SPGLQGESTAFQT 3779

Query: 793  PIGSWECSVCCVSNNAEDNKCVSCMSEKPGSS----VPASSS-------STVPVSLP-SG 840
               S   +    S      +  +     PGS+     PASS+       ST+  S P + 
Sbjct: 3780 HPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 3839

Query: 841  GSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAAS 900
            G+          G  +     +   +     L   +  PG       F +S  S  +  S
Sbjct: 3840 GTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS 3899

Query: 901  --SSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGD 958
              S    GV   S+  S++   + +           G+S +S ++   S G   S     
Sbjct: 3900 PASMTSLGVGEEST-TSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPG---STETTV 3955

Query: 959  FKFGVSSESKPEEV----KKDSKNDNFKF---GLSSGLSN-----PVSLTPFQFGV-SNL 1005
            F    ++  + EE      + +      F     +SGL+      P S    Q G+ + L
Sbjct: 3956 FPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATL 4015

Query: 1006 GQEEKKEELPKSSSAGFSFGTGVINSTPAPANT--IVTSENKSSFNLGTIETKSASVAPF 1063
               +  EE     S+  S GT +   +PA + T  +V     S  +  + ET +   +P 
Sbjct: 4016 TTADLGEESTTFPSSSGSTGTKL---SPARSTTSGLVGESTPSRLSPSSTETTTLPGSPT 4072

Query: 1064 TCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKAD 1123
            T   SE  K     T        + PA+  S+ V     T   Q  P ++ +  F     
Sbjct: 4073 TPSLSE--KSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQ--PGSTHTTAFPDSTT 4128

Query: 1124 NEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKA-TFAFGAQTSTTAD 1182
                  +P  S  +   T+   S  ST + S+ + S      P    T      T T+  
Sbjct: 4129 TSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGL 4188

Query: 1183 QGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTS----------SSNPPVATFVFGQSS 1232
              A+ P  S    S  ++ TPA+S   G+   ST+          + +PP  T V  + S
Sbjct: 4189 VEASTPTHSS-TGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVS 4247

Query: 1233 NPVSS--SAFGNTAESSTSQSLLFSQDSKLATTS--STGTAVTPFVFGPGASSNNTTTSG 1288
                S  S+   T  S++S +L  S++S    +S  +TGTA+ P            TTS 
Sbjct: 4248 TTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSP 4307

Query: 1289 FGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSST 1348
               G+T T++  GS+   G             + ++ TF  S  +         + SS  
Sbjct: 4308 ISSGSTETTALPGSTTTAGL------------SEKSTTFYSSPRSPDTTLSPASTTSSGV 4355

Query: 1349 ALFPTGSQPAPPTFGTVS--SSSQPPVFGQQPSQSAFGSGTT-----PNSSSAFQFGSST 1401
            +   T S   P +  T +  SS+  P   Q+ + S    G+T     P S++A   G  +
Sbjct: 4356 SEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPES 4415

Query: 1402 TNFNFTNNSPSGVFTFGANSSTPA-----ASAQPSGSGGFPFNQ-SPAAFTVGSNGKNVF 1455
            T F   ++SP    T     +T A     AS     S G P    SPA  T        F
Sbjct: 4416 TTF---HSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTF 4472

Query: 1456 SS 1457
             S
Sbjct: 4473 QS 4474



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 118/482 (24%), Positives = 179/482 (37%), Gaps = 93/482 (19%)

Query: 984  GLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSE 1043
            G + G S  + L+          +E ++  +  S+ +GFS  TG   +T    NT   S 
Sbjct: 123  GRAEGFSLGLPLSEQARAAGAREKERQETVINHSTFSGFSQITGSTVNTSIGGNTTSAST 182

Query: 1044 NKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRT 1103
              SS    T      SV   T  T+  K     +T  G S  +    S P A+   L  +
Sbjct: 183  PSSSDPFTTFSDYGVSVTFITGSTA-TKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPS 241

Query: 1104 EEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKES 1163
                    ++TS+  G      EPK  P+                       T  S + +
Sbjct: 242  H-------SATSVFVG------EPKTSPI-----------------------TSASMETT 265

Query: 1164 EQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPV 1223
              P   T A  ++ STT         F     S   + +PA +   G+   ST+S + P 
Sbjct: 266  ALPGSTTTAGLSEKSTT---------FYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPG 316

Query: 1224 ATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLA----TTSSTGTAVTPFVFGPGA 1279
             T      + P S++  G + ES+ S S+  S D+ L+    T SS G   T F   PG 
Sbjct: 317  PTHTI---AFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGY 373

Query: 1280 SS-----NNTTTSGFGFGATTTSSSAGSSF----------------VFGTGPSAPSASPA 1318
            +      +NTTTSG    +T   SS GS                   F + PS+   SPA
Sbjct: 374  TKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPA 433

Query: 1319 FGANQTPTFGQSQGA--SQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQ 1376
              +  T  F +      S P+       S+S+       +  P     V++++ PP    
Sbjct: 434  -PSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPP---- 488

Query: 1377 QPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNS-------PSGVF---TFGANSSTPAA 1426
             P++SA  SG    S++  +   ST   +F  +S        S  F   T    SSTP+ 
Sbjct: 489  -PARSA-TSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPST 546

Query: 1427 SA 1428
            +A
Sbjct: 547  TA 548



 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 133/623 (21%), Positives = 234/623 (37%), Gaps = 61/623 (9%)

Query: 877  AKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGV 936
            A  GT S F    T+  SS S+  ++  F  SS++ G S+  T   +             
Sbjct: 433  APSGTTSAFVKLSTTYHSSPSSTPTTH-FSASSTTLGHSEESTPVHSSPVATATTPPPAR 491

Query: 937  SSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLT 996
            S+ SG +   +   +         F  SS +     +  + + +     SS  S   +L 
Sbjct: 492  SATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALA 551

Query: 997  PFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTP-APANTIVTSENKSSFNLGTIET 1055
               +  S+LG  E       S+ +G S  +   +S+P A A T++ + +  S  +G    
Sbjct: 552  HTSYH-SSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVG---- 606

Query: 1056 KSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS 1115
              ++ +P +  + E        TK G S  +    S P        R+ +    P + TS
Sbjct: 607  -DSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSP--------RSPDTTHLPASMTS 657

Query: 1116 LVFGKKA--DNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAF 1173
                +++   +  P      +F  S  T    S +ST S S   P++      +    + 
Sbjct: 658  SGVSEESTTSHSRPGSTHTTAFPGST-TMPGLSQESTASHSSPGPTDTTLSPGSTTASSL 716

Query: 1174 GAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSN 1233
            G + +T   +  +       +N+++S    A+        S  ++ +P  +T   G+S+ 
Sbjct: 717  GPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTT 776

Query: 1234 --------------PVSSSAF--GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGP 1277
                          P ++SAF   +T    +  S+  +  S  +TTS      T +   P
Sbjct: 777  FHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSP 836

Query: 1278 GASSN-----NTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSA----------SPAFGAN 1322
            G++       + TTSG G  +TT+ SS  ++    + PS  SA          SP  G+ 
Sbjct: 837  GSTQTMHFPESDTTSGRGEESTTSHSS--TTHTISSAPSTTSALVEEPTSYHSSP--GST 892

Query: 1323 QTPTFGQSQGASQPNPPGFGSISSSTALFPTGS--QPAPPTFGTV--SSSSQPPVFGQQP 1378
             T  F  S   S  +     S SS  A   TG+   PA  T   +   S++ P   G   
Sbjct: 893  ATTHFPDSSTTSGRSEESTASHSSQDA---TGTIVLPARSTTSVLLGESTTSPISSGSME 949

Query: 1379 SQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPF 1438
            + +  GS TTP  S       S+     T  SP+   + G +  +  + ++P  +    F
Sbjct: 950  TTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAF 1009

Query: 1439 NQSPAAFTVGSNGKNVFSSSGTS 1461
              S     +  +     SS G++
Sbjct: 1010 PDSTTTPGLSRHSTTSHSSPGST 1032



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 78/298 (26%), Positives = 127/298 (42%), Gaps = 27/298 (9%)

Query: 1191 SFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFV-FGQSSNPVS-SSAFGNTAESST 1248
            +F   S  + ST  TS GG    +ST SS+ P  TF  +G S   ++ S+A  +  +SST
Sbjct: 157  TFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSST 216

Query: 1249 SQSLLFSQDSKLATT--SSTGTAVTP-------FVFGPGAS---SNNTTTSGFGFGATTT 1296
            +     S++S ++ +   +TGT + P       FV  P  S   S +  T+    G+TTT
Sbjct: 217  NSG--HSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALP-GSTTT 273

Query: 1297 SSSAGSSFVFGTGPSAP--SASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTG 1354
            +  +  S  F + P +P  + SPA   +   +   +   S+P P    +   ST + P  
Sbjct: 274  AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTM-PGV 332

Query: 1355 SQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGV 1414
            SQ +  +     S+      G     S     TT +SS  +   + TT     N + SG+
Sbjct: 333  SQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGY---TKTTRLP-DNTTTSGL 388

Query: 1415 F--TFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVF-SSSGTSFSGRKIKT 1469
               +   +SST +     S S        P  F    + K+   + SGT+ +  K+ T
Sbjct: 389  LEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLST 446



 Score = 39.3 bits (90), Expect = 0.028
 Identities = 143/664 (21%), Positives = 237/664 (35%), Gaps = 113/664 (17%)

Query: 94   SNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESP-ALHCQPST 152
            SN T GR       S T   STT T S+ P   +           +++E P + H  P +
Sbjct: 4570 SNTTSGR----GEESTTSHSSTTHTISSAPSTTS-----------ALVEEPTSYHSSPGS 4614

Query: 153  SSA--FPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASDKDITVSKNTSLPPLWS- 209
            ++   FP  S+     +E   ST+ H   + + T    +R++   +     TS  P+ S 
Sbjct: 4615 TATTHFPDSSTTSGRSEE---STASHSSQDATGTIVLPARSTTSVLLGESTTS--PISSG 4669

Query: 210  -------PEAERSHSLSQHTATSSKKPAFNLSA-FGTLSPSLGNSSILKTSQLGDSPFYP 261
                   P +  +  LS+ + T    P+   +  F   S +LG S   +++ +  SP   
Sbjct: 4670 SMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSE--ESTTVHSSPVAT 4727

Query: 262  GKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLEKMSSP 321
              T     +      +     + +P   Q      S+ + G +  +      +   +SSP
Sbjct: 4728 ATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSP 4787

Query: 322  LADAKRIPSIVSSPLNSPLDRSGIDITDFQAK-------REKVDSQYPPVQRLMTPKPVS 374
             +      ++V  P +       I  T F           E   S   P    +TP P  
Sbjct: 4788 PSTTS---ALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAH 4844

Query: 375  ------IATNRSVYFKP-SLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNRE-------- 419
                  IA + + Y  P S+  +     T   +  K +  Y  + +P Q           
Sbjct: 4845 FTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSS 4904

Query: 420  ---QRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKIS 476
               +  S +S    +   A   S+   G    + +E T F  SKP   E    P      
Sbjct: 4905 ISGEPTSLYSQAESTHTTAFPASTTTSG----LSQESTTF-HSKPGSTETTLSPG----- 4954

Query: 477  LPITSSSLP---TFNFSSPEITTSSPSPINSSQALTNKVQMT---SPSSTGSPMFKFSSP 530
              IT+SS     T   S P    S+ SP +++    ++   T   SP ST +  F  S+ 
Sbjct: 4955 -SITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNT 5013

Query: 531  IVKSTEANVLPPSSIGFTFSV-PVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTP 589
            +   ++ +   P S GFT +V P   T    G  ST        A H    +S++   T 
Sbjct: 5014 MSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQEST--------AFH----SSSDATGTT 5061

Query: 590  PEDCEGPFRPAEILKEGSVLDILKSPGF-----ASPKIDSVAAQPTA--TSPVVYTRPAI 642
            P         ++++ E +   I  SP +     AS     +  + T   TSP  +T   +
Sbjct: 5062 PLPARS--TASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSP-SFTSTIV 5118

Query: 643  SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702
            S+ S   +  G   + G  W    C+        +C       LSP ++     +ETP K
Sbjct: 5119 STESLETLAPG-LCQEGQIWNGKQCVCPQGYVGYQC-------LSPLESFP---VETPEK 5167

Query: 703  SGKT 706
               T
Sbjct: 5168 LNAT 5171


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 216/1057 (20%), Positives = 377/1057 (35%), Gaps = 116/1057 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            TSS     + +  E TT S     ++ A T   + T+ S+TGS M       V +  +  
Sbjct: 130  TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM-----TTVFTAGSET 184

Query: 540  LPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598
            + PS+ G  T +V  A +   + S++  E   +S+AH  TT  ST   +T      G   
Sbjct: 185  ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244

Query: 599  PAEI------------------LKEGSVLDILKSPGFASPKIDSVAAQPTATS------- 633
                                    E S      + GF +    +  ++PT  S       
Sbjct: 245  TVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETT 304

Query: 634  ------PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLS 687
                  P        SS  ++    G      S+   +T  +    ++    +   ++ S
Sbjct: 305  MASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETS 364

Query: 688  PRDT-------AKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPE 738
               T       A   G ET   S  G    + S TG       +  +    TC   ++  
Sbjct: 365  TDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMT 424

Query: 739  AIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWE 798
            A+     ET    T     +T+   S+S  T  ++  S T T  T G   K     GS  
Sbjct: 425  AVSTTVFETTTAST-EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSET 483

Query: 799  CSVC-----------------CVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS---L 837
             +                     S    +   VS   SE    S   S ++TV  +    
Sbjct: 484  TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 838  PSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSS---- 892
             +  + GLE      EGS   E+  V      T   + E +   T +   G +T++    
Sbjct: 544  TTVSTTGLETTTTSTEGS---EMTTVSTTGAETTTDSTEGSGT-TAASTAGSETTTVSTA 599

Query: 893  SSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKF---GDQGGFKIGVS---SDSGSINPM 946
             S N+ AS++     S+S++G   T  ST + +      +G     VS   S++  ++  
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 947  SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006
                  +   G     VS+      V  +         ++   +  VS T    G     
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTT----GSETTT 714

Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066
               +  E+  +S  G    T     +     +   SE  S+   G+  T +++ +  T  
Sbjct: 715  TSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTM 774

Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126
             S    E   A+  G     V  AS    +VF      E  +  + ST+           
Sbjct: 775  ASIMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAG 829

Query: 1127 PKCQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTAD 1182
             +  P  + G+  +  T  E S  +T S   S T  +  ES +   AT   G++T+T + 
Sbjct: 830  SETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTAST 888

Query: 1183 QGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGN 1242
            +G+     S    +  S +T A++ G  I   ST+ S    A+    +++   +  +   
Sbjct: 889  EGSETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELT 944

Query: 1243 TAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS 1302
            T  ++ S+++  S +    TT +T  + T      G+ +   +T+G     TTT+S  GS
Sbjct: 945  TVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGS 1001

Query: 1303 --SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPP 1360
              + V  TG    + S   G   T T  +    +     G    S +TA++ TGS+    
Sbjct: 1002 ETTTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE---- 1052

Query: 1361 TFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGAN 1420
            T  T +  S+        S++   S     +++    GS TT  +   +  + V+  G+ 
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 1421 SSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457
            ++T +     + +     +++  A T GS    VF++
Sbjct: 1113 TTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149



 Score = 94.4 bits (233), Expect = 7e-19
 Identities = 201/994 (20%), Positives = 377/994 (37%), Gaps = 100/994 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T++S   F  ++   T S P+  ++  + T       P +T           V +  +  
Sbjct: 274  TTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET 333

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599
            +  S++G   +     T   +GS +T   I+ S     T+ +ST   +T     EG    
Sbjct: 334  IRASTVGSETT-----TVSTTGSETTTASIMGSE----TSTDSTTGSETTTASTEGS-ET 383

Query: 600  AEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF-----SSSGIGFGE 654
                 EGS    + + G  +  +    ++ T T        A+S+      ++S  G   
Sbjct: 384  TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443

Query: 655  SLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-----SPRDTAKQTGIETPN--KSGKTT 707
            ++ + S  +  T   +   T     A    K      S   TA  TG+ET      G  T
Sbjct: 444  TIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDT 503

Query: 708  LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767
             +AS  G         G+         ++   +     ET    T      T T  +E +
Sbjct: 504  TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLE--TTTTSTEGS 561

Query: 768  ETMTASSSSCTVTT-GTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
            E  T S++    TT  T G G       GS   +V     ++E+    +  SE   +S  
Sbjct: 562  EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA--DSENTTASTADSETTSASTT 619

Query: 827  ASSSSTVPVSLPSGGSLGLEKFKKPEGSW-DCELCLVQNKADSTKCLACESAKPGTKSGF 885
             S ++T   +     +   E  +    S  D E  +V          + E ++  T S  
Sbjct: 620  GSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSA- 678

Query: 886  KGFDTSSSSSNSAASSSFKFGVSS---SSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGS 942
             G +T+ S+  S  ++    G  +   S++G   T TST         G +I  +S +GS
Sbjct: 679  TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTE--------GSEITTASITGS 730

Query: 943  --INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQF 1000
                  +EG + +    +     S+ +   E    S   + +  ++S + +  ++     
Sbjct: 731  ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSS-ETTMASIMGSETTMA---- 785

Query: 1001 GVSNLGQEEKKEELPKSSSAGF---SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS 1057
              S +G E  K     S        +  T + ++T +   T+ T+ ++      TI   +
Sbjct: 786  --STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE------TIPAST 837

Query: 1058 ASVAPFTCKTSEAKKEEMPATKGG-FSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSL 1116
            A     T  ++E  +    +T+G   +  + E +   +A+      T    +   T+T+ 
Sbjct: 838  AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897

Query: 1117 VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQ 1176
              G +      +   + +      T  E ++ ST     T  S + SE    +T   G++
Sbjct: 898  TEGSETTTASTEGSEITTVST---TGSETTTASTEGSETTTASTEGSELTTVSTT--GSE 952

Query: 1177 TSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVS 1236
            T T + +G+     + +     S +T A++AG      ST+ S    A+ + G  +  VS
Sbjct: 953  TITVSAEGSETTTVTTMG----SETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVS 1007

Query: 1237 SSAFGNTAESST-SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATT 1295
            S+    T  S+T +++ + S +    TT +T  + T  V+  G+ +  T+T G     TT
Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG---SETT 1064

Query: 1296 TSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGS 1355
            T S+ GS             + A  A+   T   + G+        GS   +T ++ TGS
Sbjct: 1065 TVSTTGSE-----------TTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGS 1111

Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415
            +       T ++S++        S++   S T+  +++A   GS  T    T +  + V 
Sbjct: 1112 K-------TTTASTEG-------SEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVS 1157

Query: 1416 TFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGS 1449
            T G+ ++T +A+   + +     +++  A T GS
Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAGS 1191



 Score = 88.6 bits (218), Expect = 4e-17
 Identities = 188/993 (18%), Positives = 361/993 (36%), Gaps = 105/993 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T S   T +    E +T S +   ++ A T   + T+ S+ GS     S+   ++T  ++
Sbjct: 349  TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598
                +     +    + +E++  S+T+ E   +S+     T+ ST+  +T     EG   
Sbjct: 409  TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 462

Query: 599  PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658
               +   GS      + G  +    +   + T     V+T   I S +++    G    A
Sbjct: 463  TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 515

Query: 659  GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716
             S+   +   +  + ++N  ++   ++ +   T   TG+ET   S  G    + S TG  
Sbjct: 516  VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 572

Query: 717  DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776
                   G+         ++   +     E     T      T +  +  +ET TAS++S
Sbjct: 573  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 630

Query: 777  CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836
               TT +           GS   +V   + ++E     +  SE+  +S   S ++TV  +
Sbjct: 631  SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 679

Query: 837  LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896
                   G E     EGS    + +  ++         E+    T+       + + S  
Sbjct: 680  -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 897  SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956
            + AS+      ++S+ G   T  ST     G +       SS++   + M      +  I
Sbjct: 733  TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 788

Query: 957  GDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPK 1016
            G     VS+ S           +N +  ++S  ++  +       VS  G E     +P 
Sbjct: 789  GSETTKVSTASSKMTTVF---TENSETTIASTTASETTT------VSTAGSET----IPA 835

Query: 1017 SSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMP 1076
            S++      T    ST     T  ++E   +    T  +++ +      +T+ A  E   
Sbjct: 836  STAGS---ETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSE 892

Query: 1077 ATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKK---ADNEEPKCQPVF 1133
             T           AS   + +  +  T  +     T+T+   G +   A  E  +   V 
Sbjct: 893  TTTTSTEGSETTTASTEGSEITTVSTTGSE-----TTTASTEGSETTTASTEGSELTTVS 947

Query: 1134 SFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAF--GAQTSTTADQGAAKPVFS 1191
            + G+   T     S++T   +M   +   S   ++ T     G++T+T + +G+     S
Sbjct: 948  TTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVS 1007

Query: 1192 FLNN-----SSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246
               +     S++ + T  TS  G    + T++ +   A +  G  +   S+     T  S
Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVS 1067

Query: 1247 STSQSLLFSQDSKL-----------ATTSSTGTAVTPFVFGPGA---------------- 1279
            +T      +  + L            TT+ST  + T  V+  G+                
Sbjct: 1068 TTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1280 --SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPN 1337
              SS  TT S  G   TT  ++   +    T  S  + S A G+  T T  +    +  +
Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS 1187

Query: 1338 PPGFGSISSSTA--LFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAF 1395
              G  + ++STA     T S     T    +S S+        S+++  S     +++AF
Sbjct: 1188 TAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAF 1247

Query: 1396 QFGSSTTNFNFTNNSPSGVFTFGANSSTPAASA 1428
              GS TT  +  +  P+     G+ ++T + +A
Sbjct: 1248 IIGSETTIASTASLEPTATSLTGSETTTVSITA 1280



 Score = 85.1 bits (209), Expect = 5e-16
 Identities = 157/800 (19%), Positives = 285/800 (35%), Gaps = 65/800 (8%)

Query: 691  TAKQTGIETP-NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749
            TA   G ET  + +G  T + S TG        +G+         ++         ET  
Sbjct: 87   TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146

Query: 750  PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809
              T      T T  +  +ET  AS++   +TT      +         E +   VS    
Sbjct: 147  VSTVGSE--TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTT--VSTAGS 202

Query: 810  DNKCVSCMSEKPGSSVPASSSSTVPVSLPSG----GSLGLEKFKKPEGSWDCELCLVQNK 865
            +   VS    +  ++  A S +T   ++ S      + G E      GS   E      +
Sbjct: 203  ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---ETTAASTE 259

Query: 866  ADSTKCLACESAKPGTKSGFKGFDTSSSSSNSA----ASSSFKFGVSSSSSGPSQTLTST 921
               T     E +K  T S   GF+T+++S+  +    AS+       +S+ GP  T  ST
Sbjct: 260  DSETNTAFTEDSKTTTAST-TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVST 318

Query: 922  GN------FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975
             +      F  G +      V S++ +++        +  +G      S+          
Sbjct: 319  ASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTAST 378

Query: 976  SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035
              ++          +  VS T  +    ++   E      + S       T    +T + 
Sbjct: 379  EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438

Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095
              + +T  + S     T  T+ +     T   SE K     A   G          L + 
Sbjct: 439  EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT----AYTTGSETTTASNTGLETT 494

Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK-----DENSSKST 1150
            +VF +G          + T+ V    ++          S   SE T       E ++ ST
Sbjct: 495  TVFTIGSDTTTASTEGSETTAVSATGSE------MTTVSTEGSENTTVSTTGSETTTVST 548

Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210
                 T  S + SE    +T   GA+T+T + +G              S +T A++AG  
Sbjct: 549  TGLETTTTSTEGSEMTTVSTT--GAETTTDSTEG--------------SGTTAASTAGSE 592

Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV 1270
                ST+ S    A+    ++++  ++ +   TA +++S++   S +    TT ST  + 
Sbjct: 593  TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652

Query: 1271 TPFVFGPGA--------SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGAN 1322
            T  V   G+         S  TT S  G   T ++  +G++ V  TG      S   G+ 
Sbjct: 653  TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-GSE 711

Query: 1323 QTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380
             T T  +    +  +  G  + ++ST  +   T S     T    ++ S+        S+
Sbjct: 712  TTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771

Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440
            +   S     ++ A   GS TT  +  ++  + VFT  + ++  + +A  + +     ++
Sbjct: 772  TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 1441 SPAAFTVGSNGKNVFSSSGT 1460
            +  A T GS      S+ G+
Sbjct: 832  TIPASTAGSETTTTTSTEGS 851



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 219/1063 (20%), Positives = 383/1063 (36%), Gaps = 157/1063 (14%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T S   T + +  E TT+       +   T   + T+ S+ GS +   S+   ++T A+ 
Sbjct: 399  TGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTAST 458

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSST------LEPIISSSAHHVTTVNSTNCKKTPPEDC 593
                +   T +    KTA  +GS +T      LE     +    TT  ST   +T     
Sbjct: 459  EGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSA 518

Query: 594  EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSP-------VVYTRPAISSFS 646
             G      +  EGS    + + G  +  + +   + T TS        V  T    ++ S
Sbjct: 519  TGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDS 577

Query: 647  SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706
            + G G   +  AGS    +T  +    ++N   +   ++ +   +A  TG ET   S  +
Sbjct: 578  TEGSGTTAASTAGS----ETTTVSTADSENTTASTADSETT---SASTTGSETTTASTTS 630

Query: 707  TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766
            + + + +  G +    + T D +T +V                  T  +R +T T   E 
Sbjct: 631  SETTTASTEGSE-TTTVSTTDSETTMVST----------------TGSERTITST---EG 670

Query: 767  AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSN-----NAEDNKCVSCM---S 818
            +ET T S++    T  T G G       GS    V    +     + E ++  +     S
Sbjct: 671  SETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGS 730

Query: 819  EKPGSSVPASSSSTVPVS---LPSGGSLGLEKFKKPEGSWDCELCLVQ-NKADSTKCLAC 874
            E   +S   S ++T         S  + G E       S +  +  +  ++      +  
Sbjct: 731  ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGS 790

Query: 875  ESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSG----PSQTLTSTGNFKFGDQG 930
            E+ K  T S       + +S  + AS++     + S++G    P+ T  S        +G
Sbjct: 791  ETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEG 850

Query: 931  GFKIGVS---SDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSS 987
                  S   S++ + +  S     +  IG      S+E           ++        
Sbjct: 851  SETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG 910

Query: 988  GLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVT--SENK 1045
                 VS T    G        +  E   +S+ G    T  +++T +   T+    SE  
Sbjct: 911  SEITTVSTT----GSETTTASTEGSETTTASTEGSELTT--VSTTGSETITVSAEGSETT 964

Query: 1046 SSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGR--- 1102
            +   +G+  T +++    T   S A  E   A+  G     V      + +V   G    
Sbjct: 965  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024

Query: 1103 ---TEEKQQEPVTS----TSLVFGKKADN-----EEPKCQPVFSFGNSEQTKD----ENS 1146
               TE  +   VT+    T+ V+   ++      E  +   V + G+   T      E +
Sbjct: 1025 ITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084

Query: 1147 SKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPAT- 1205
            + ST     T  S   SE      +  G++T+T + +G+     S  ++ ++++ST  + 
Sbjct: 1085 TVSTSGSGTTTASTAGSE--TTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSE 1142

Query: 1206 ----------SAGGGIFGS--STSSSNPPVATFVFGQSSNPVSSSAFGN-TAESSTSQSL 1252
                      +      GS  +TSS+    AT    + S   ++S  G+ T  +ST+ S 
Sbjct: 1143 MTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS- 1201

Query: 1253 LFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS----SFVFG- 1307
                     TT+ST  + T      G+ +N   T+G     T+T SSAGS    +F+ G 
Sbjct: 1202 -------ETTTASTAGSETTTASTSGSETNTACTTG---SETSTPSSAGSETNTAFIIGS 1251

Query: 1308 ------TGPSAPSASPAFGANQTPTFGQSQGAS---------------------QP--NP 1338
                  T    P+A+   G+  T     + GA+                     QP  N 
Sbjct: 1252 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1311

Query: 1339 PGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFG 1398
            P  G+ ++ T L  + S    P     +S++   V G   + S  G+ T   SS+    G
Sbjct: 1312 PMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHG 1371

Query: 1399 SSTTNFNFTNNSPS-----GVFTFGAN----SSTPAASAQPSG 1432
              TT  +    + S     G  + G N    S TP    +PSG
Sbjct: 1372 VRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPSG 1414



 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 193/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%)

Query: 478  PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537
            P   S+  T + +  E TT       ++ A T   + T+PS TGS     S    + T  
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 68

Query: 538  NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582
            +     +   + +     TA ++GS +T+               E  + S+    TT NS
Sbjct: 69   STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS 128

Query: 583  TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642
            T   +T      G         E + +  + S    +   DS     + T   + T    
Sbjct: 129  TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 643  SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702
             S + +    G      S+   +T  +    ++    +   ++ +   T      +    
Sbjct: 181  GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 240

Query: 703  SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758
              +TT+S +G+           T D +T       +K         ET    T   +  +
Sbjct: 241  GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295

Query: 759  TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810
              T+ SE+        ET   S++S  VTT      +  +   +GS       VS    +
Sbjct: 296  ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 352

Query: 811  NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869
                S M SE    S   S ++T         +   E  +    S         +  DS 
Sbjct: 353  TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412

Query: 870  KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923
                C      T      F+T+++S+       A++S  +   +S+    + T+T+ G+ 
Sbjct: 413  TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 472

Query: 924  FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979
             K     G +   +S++G    ++  +      +   G     VS+            ++
Sbjct: 473  TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532

Query: 980  NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039
            N     +   +  VS T    G+       +  E+   S+ G    T   +ST     T 
Sbjct: 533  NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 585

Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099
             ++    +  + T ++++ + +    +T+ A       T    +      AS   +    
Sbjct: 586  ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 645

Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156
            +  T+   +  + ST+         E  +   V + G+      E S  +T S +    T
Sbjct: 646  VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 703

Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208
            K S   SE    +T           G++T+T + +G+     S    +  S +T A++ G
Sbjct: 704  KVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 759

Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265
                 +ST+SS   +A+ +   S   ++S+    T + ST+ S    +F+++S+    S+
Sbjct: 760  SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817

Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317
            T        TA +  +    A S  TTT+      TTT+S+ GS +    T  S  + + 
Sbjct: 818  TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877

Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375
              G+  T    +    +  +  G  + ++ST  +   T S     T    +  S+     
Sbjct: 878  TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937

Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435
             + S+    S T   + +    GS TT      +  +   T G+ ++T + +   + +  
Sbjct: 938  TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 997

Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460
               +++    + GS    V S++GT
Sbjct: 998  IEGSETTTVSSTGSETTTV-STTGT 1021



 Score = 57.8 bits (138), Expect = 8e-08
 Identities = 166/870 (19%), Positives = 303/870 (34%), Gaps = 96/870 (11%)

Query: 476  SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535
            S   T S   T + +S E TT+S     ++   T   + T  S+TGS     S+   ++T
Sbjct: 615  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 536  -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586
                   E  V    S   T S+  ++T ++S  GS +T     S+    +TT + T   
Sbjct: 675  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---TTSTEGSEITTASITG-S 730

Query: 587  KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646
            +T     EG         EGS      + G      ++  A  T++   + +     +  
Sbjct: 731  ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 784

Query: 647  SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706
            +S IG   +  + +S +  T   +N  ++    +  A++ +   TA    I       +T
Sbjct: 785  ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 707  TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766
            T + S  G         G+         ++      +  ET    T  + + T T  +E 
Sbjct: 843  TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 900

Query: 767  AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
            +ET TAS+    +TT            + +        S    +    S    +  ++V 
Sbjct: 901  SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 947

Query: 827  ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886
             + S T+ VS               EGS    +  + ++  +      E+    T     
Sbjct: 948  TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 887  GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946
               +   S  +  SS+     + S++G   T+TST     G +        S++ ++   
Sbjct: 994  TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAVYTT 1049

Query: 947  SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006
                  +   G     VS+          +  +      S   +   S    +     + 
Sbjct: 1050 GSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYIT 1109

Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTI-ETKSASVAPFTC 1065
              +      + S A        +++T +   T  T+ ++ +    T+ ET + S      
Sbjct: 1110 GSKTTTASTEGSEA------TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163

Query: 1066 KTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNE 1125
             TS A   E   T       + E +   +AS      T        T+T+   G +    
Sbjct: 1164 TTSSAAGSEATTT-------STEGSETTTASTAGSETTTASTAGSETTTASTAGSETT-- 1214

Query: 1126 EPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGA 1185
                        +  +  E ++  T     + PS   SE      F  G++T T A   +
Sbjct: 1215 -----------TASTSGSETNTACTTGSETSTPSSAGSE--TNTAFIIGSET-TIASTAS 1260

Query: 1186 AKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF----- 1240
             +P  + L  + S ++T + +A G    S+T SS   V T     S  P++++       
Sbjct: 1261 LEPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRT 1318

Query: 1241 -GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTS 1297
             G    +S+S ++    D   +  S T   +     G G S+   ++TTS  G   TT S
Sbjct: 1319 TGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGS 1378

Query: 1298 SSAGSSFVF-GTGPSAPSASPAFGANQTPT 1326
            +   +S  F  TGP +   +     + TPT
Sbjct: 1379 TREPTSSTFQETGPVSMGTN-TVSMSHTPT 1407



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 50/197 (25%), Positives = 80/197 (40%), Gaps = 29/197 (14%)

Query: 1277 PGASSNNTTTSGFGF---------GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327
            P A SN TT S  G            TTT+S+AGS     T PS   +     +      
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET---TTPSPTGSQTTIVSISGSEI 65

Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ-SAFGSG 1386
              +  A   N     + S +T     GS+    T G  S ++   + G + +  SA GS 
Sbjct: 66   TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG--SETTTVSITGTETTMVSAMGSE 123

Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446
            TT NS+++    S TT  +   +  + V T G+ ++T   +           +++ AA T
Sbjct: 124  TTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYTAD----------SETTAAST 169

Query: 1447 VGSNGKNVFSSSGTSFS 1463
             GS    VF++   + +
Sbjct: 170  TGSEMTTVFTAGSETIT 186


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 207/1055 (19%), Positives = 376/1055 (35%), Gaps = 112/1055 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            TSS     + +  E TT S     ++ A T   + T+ S+TGS M    + +  +    +
Sbjct: 130  TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM----TTVFTAGSETI 185

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599
             P ++   T +V  A +   + S++  E   +S+AH  TT  ST   +T      G    
Sbjct: 186  TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 600  AE------------------ILKEGSVLDILKSPGFASPKIDSVAAQPTATS-------- 633
                                   E S      + GF +    +  ++PT  S        
Sbjct: 246  VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTM 305

Query: 634  -----PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-- 686
                 P        SS  ++    G      S+   +T  +    ++    +   ++   
Sbjct: 306  ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365

Query: 687  -----SPRDTAKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEA 739
                 S   TA   G ET   S  G    + S TG       +  +    TC   ++  A
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 740  IKCVACETPKPGT------------------CVKRALTLTVVSESAETMTA-SSSSCTVT 780
            +     ET    T                    + + T TV +  +ET TA ++ S T T
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485

Query: 781  TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS--- 836
                G        IGS        S    +   VS   SE    S   S ++TV  +   
Sbjct: 486  ASNTGLETTTVFTIGS---DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSE 542

Query: 837  LPSGGSLGLE-KFKKPEGS-------WDCELCLVQNKADSTKCLACESAKPGTKSGFKGF 888
              +  + GLE      EGS          E      +   T   +   ++  T S     
Sbjct: 543  TTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSE 602

Query: 889  DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE 948
            +T++S+++S  +S+   G  ++++  + + T+T + + G +        S++  ++    
Sbjct: 603  NTTASTADSETTSASTTGSETTTASTTSSETTTASTE-GSETTTVSTTDSETTMVSTTGS 661

Query: 949  GFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQE 1008
                +   G     VS+      V  +         ++   +  VS T    G       
Sbjct: 662  ERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTT----GSETTTTS 716

Query: 1009 EKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTS 1068
             +  E+  +S  G    T     +     +   SE  S+   G+  T +++ +  T   S
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 1069 EAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPK 1128
                E   A+  G     V  AS    +VF      E  +  + ST+            +
Sbjct: 777  IMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAGSE 831

Query: 1129 CQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTADQG 1184
              P  + G+  +  T  E S  +T S   S T  +  ES +   AT   G++T+T + +G
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTASTEG 890

Query: 1185 AAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTA 1244
            +     S    +  S +T A++ G  I   ST+ S    A+    +++   +  +   T 
Sbjct: 891  SETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTV 946

Query: 1245 ESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-- 1302
             ++ S+++  S +    TT +T  + T      G+ +   +T+G     TTT+S  GS  
Sbjct: 947  STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGSET 1003

Query: 1303 SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF 1362
            + V  TG    + S   G   T T  +    +     G    S +TA++ TGS+    T 
Sbjct: 1004 TTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE----TT 1054

Query: 1363 GTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS 1422
             T +  S+        S++   S     +++    GS TT  +   +  + V+  G+ ++
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114

Query: 1423 TPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457
            T +     + +     +++  A T GS    VF++
Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149



 Score = 95.1 bits (235), Expect = 4e-19
 Identities = 206/1019 (20%), Positives = 385/1019 (37%), Gaps = 104/1019 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T++S   F  ++   T S P+  ++  + T       P +T           V +  +  
Sbjct: 274  TTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET 333

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599
            +  S++G   +     T   +GS +T   I+ S     T+ +ST   +T     EG    
Sbjct: 334  IRASTVGSETT-----TVSTTGSETTTASIMGSE----TSTDSTTGSETTTASTEGS-ET 383

Query: 600  AEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF-----SSSGIGFGE 654
                 EGS    + + G  +  +    ++ T T        A+S+      ++S  G   
Sbjct: 384  TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443

Query: 655  SLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-----SPRDTAKQTGIETPN--KSGKTT 707
            ++ + S  +  T   +   T     A    K      S   TA  TG+ET      G  T
Sbjct: 444  TIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDT 503

Query: 708  LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767
             +AS  G         G+         ++   +     ET    T      T T  +E +
Sbjct: 504  TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLE--TTTTSTEGS 561

Query: 768  ETMTASSSSCTVTT-GTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
            E  T S++    TT  T G G       GS   +V     ++E+    +  SE   +S  
Sbjct: 562  EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA--DSENTTASTADSETTSASTT 619

Query: 827  ASSSSTVPVSLPSGGSLGLEKFKKPEGSW-DCELCLVQNKADSTKCLACESAKPGTKSGF 885
             S ++T   +     +   E  +    S  D E  +V          + E ++  T S  
Sbjct: 620  GSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSA- 678

Query: 886  KGFDTSSSSSNSAASSSFKFGVSS---SSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGS 942
             G +T+ S+  S  ++    G  +   S++G   T TST         G +I  +S +GS
Sbjct: 679  TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTE--------GSEITTASITGS 730

Query: 943  --INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQF 1000
                  +EG + +    +     S+ +   E    S   + +  ++S + +  ++     
Sbjct: 731  ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSS-ETTMASIMGSETTMA---- 785

Query: 1001 GVSNLGQEEKKEELPKSSSAGF---SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS 1057
              S +G E  K     S        +  T + ++T +   T+ T+ ++      TI   +
Sbjct: 786  --STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE------TIPAST 837

Query: 1058 ASVAPFTCKTSEAKKEEMPATKGG-FSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSL 1116
            A     T  ++E  +    +T+G   +  + E +   +A+      T    +   T+T+ 
Sbjct: 838  AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897

Query: 1117 VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQ 1176
              G +      +   + +      T  E ++ ST     T  S + SE    +T   G++
Sbjct: 898  TEGSETTTASTEGSEITTVST---TGSETTTASTEGSETTTASTEGSELTTVSTT--GSE 952

Query: 1177 TSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVS 1236
            T T + +G+     + +     S +T A++AG      ST+ S    A+ + G  +  VS
Sbjct: 953  TITVSAEGSETTTVTTMG----SETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVS 1007

Query: 1237 SSAFGNTAESST-SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATT 1295
            S+    T  S+T +++ + S +    TT +T  + T  V+  G+ +  T+T G     TT
Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG---SETT 1064

Query: 1296 TSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGS 1355
            T S+ GS             + A  A+   T   + G+        GS   +T ++ TGS
Sbjct: 1065 TVSTTGSE-----------TTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGS 1111

Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415
            +       T ++S++        S++   S T+  +++A   GS  T    T +  + V 
Sbjct: 1112 K-------TTTASTEG-------SEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVS 1157

Query: 1416 TFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSG----TSFSGRKIKTA 1470
            T G+ ++T +A+   + +     +++  A T GS      ++       S SG +  TA
Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTA 1216



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 186/973 (19%), Positives = 359/973 (36%), Gaps = 75/973 (7%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T S   T +    E +T S +   ++ A T   + T+ S+ GS     S+   ++T  ++
Sbjct: 349  TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598
                +     +    + +E++  S+T+ E   +S+     T+ ST+  +T     EG   
Sbjct: 409  TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 462

Query: 599  PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658
               +   GS      + G  +    +   + T     V+T   I S +++    G    A
Sbjct: 463  TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 515

Query: 659  GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716
             S+   +   +  + ++N  ++   ++ +   T   TG+ET   S  G    + S TG  
Sbjct: 516  VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 572

Query: 717  DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776
                   G+         ++   +     E     T      T +  +  +ET TAS++S
Sbjct: 573  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 630

Query: 777  CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836
               TT +           GS   +V   + ++E     +  SE+  +S   S ++TV  +
Sbjct: 631  SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 679

Query: 837  LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896
                   G E     EGS    + +  ++         E+    T+       + + S  
Sbjct: 680  -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 897  SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956
            + AS+      ++S+ G   T  ST     G +       SS++   + M      +  I
Sbjct: 733  TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 788

Query: 957  GDFKFGVSS-ESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELP 1015
            G     VS+  SK   V  ++         +S  +   +        S  G E       
Sbjct: 789  GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT--- 845

Query: 1016 KSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEM 1075
             +S+ G    T     +     +  +SE  ++  +G+  T +++    T  TS    E  
Sbjct: 846  -TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 1076 PATKGGFSFGNVEPASLPSASVFVLGR------TEEKQQEPVTST-SLVFGKKADNEEPK 1128
             A+  G     V      + +    G       TE  +   V++T S      A+  E  
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 1129 CQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATF--AFGAQTSTTADQGAA 1186
               V + G+   T     S++T   +    +   S + ++ T   + G++T+T +  G  
Sbjct: 965  T--VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1022

Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246
              + S    +  S +T  T+AG       T+ S     +    +++   ++ +   TA +
Sbjct: 1023 TTITS----TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078

Query: 1247 STSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSG-------FGFGATTTSSS 1299
            +  ++   S      TT+ST  + T  V+  G+ +   +T G            TTT+S+
Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAST 1138

Query: 1300 AGSSF--VFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTA--LFPTGS 1355
             GS    VF T     + S   G+  T +      A+  +  G  + ++STA     T S
Sbjct: 1139 TGSEMTTVFTTVSETTTVS-TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1197

Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415
                 T    +S S+        S+++  S     +++AF  GS TT  +  +  P+   
Sbjct: 1198 TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATS 1257

Query: 1416 TFGANSSTPAASA 1428
              G+ ++T + +A
Sbjct: 1258 LTGSETTTVSITA 1270



 Score = 85.1 bits (209), Expect = 5e-16
 Identities = 157/800 (19%), Positives = 285/800 (35%), Gaps = 65/800 (8%)

Query: 691  TAKQTGIETP-NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749
            TA   G ET  + +G  T + S TG        +G+         ++         ET  
Sbjct: 87   TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146

Query: 750  PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809
              T      T T  +  +ET  AS++   +TT      +         E +   VS    
Sbjct: 147  VSTVGSE--TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTT--VSTAGS 202

Query: 810  DNKCVSCMSEKPGSSVPASSSSTVPVSLPSG----GSLGLEKFKKPEGSWDCELCLVQNK 865
            +   VS    +  ++  A S +T   ++ S      + G E      GS   E      +
Sbjct: 203  ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---ETTAASTE 259

Query: 866  ADSTKCLACESAKPGTKSGFKGFDTSSSSSNSA----ASSSFKFGVSSSSSGPSQTLTST 921
               T     E +K  T S   GF+T+++S+  +    AS+       +S+ GP  T  ST
Sbjct: 260  DSETNTAFTEDSKTTTAST-TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVST 318

Query: 922  GN------FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975
             +      F  G +      V S++ +++        +  +G      S+          
Sbjct: 319  ASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTAST 378

Query: 976  SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035
              ++          +  VS T  +    ++   E      + S       T    +T + 
Sbjct: 379  EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438

Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095
              + +T  + S     T  T+ +     T   SE K     A   G          L + 
Sbjct: 439  EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT----AYTTGSETTTASNTGLETT 494

Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK-----DENSSKST 1150
            +VF +G          + T+ V    ++          S   SE T       E ++ ST
Sbjct: 495  TVFTIGSDTTTASTEGSETTAVSATGSE------MTTVSTEGSENTTVSTTGSETTTVST 548

Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210
                 T  S + SE    +T   GA+T+T + +G              S +T A++AG  
Sbjct: 549  TGLETTTTSTEGSEMTTVSTT--GAETTTDSTEG--------------SGTTAASTAGSE 592

Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV 1270
                ST+ S    A+    ++++  ++ +   TA +++S++   S +    TT ST  + 
Sbjct: 593  TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652

Query: 1271 TPFVFGPGA--------SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGAN 1322
            T  V   G+         S  TT S  G   T ++  +G++ V  TG      S   G+ 
Sbjct: 653  TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-GSE 711

Query: 1323 QTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380
             T T  +    +  +  G  + ++ST  +   T S     T    ++ S+        S+
Sbjct: 712  TTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771

Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440
            +   S     ++ A   GS TT  +  ++  + VFT  + ++  + +A  + +     ++
Sbjct: 772  TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 1441 SPAAFTVGSNGKNVFSSSGT 1460
            +  A T GS      S+ G+
Sbjct: 832  TIPASTAGSETTTTTSTEGS 851



 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 193/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%)

Query: 478  PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537
            P   S+  T + +  E TT       ++ A T   + T+PS TGS     S    + T  
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 68

Query: 538  NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582
            +     +   + +     TA ++GS +T+               E  + S+    TT NS
Sbjct: 69   STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS 128

Query: 583  TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642
            T   +T      G         E + +  + S    +   DS     + T   + T    
Sbjct: 129  TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 643  SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702
             S + +    G      S+   +T  +    ++    +   ++ +   T      +    
Sbjct: 181  GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 240

Query: 703  SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758
              +TT+S +G+           T D +T       +K         ET    T   +  +
Sbjct: 241  GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295

Query: 759  TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810
              T+ SE+        ET   S++S  VTT      +  +   +GS       VS    +
Sbjct: 296  ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 352

Query: 811  NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869
                S M SE    S   S ++T         +   E  +    S         +  DS 
Sbjct: 353  TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412

Query: 870  KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923
                C      T      F+T+++S+       A++S  +   +S+    + T+T+ G+ 
Sbjct: 413  TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 472

Query: 924  FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979
             K     G +   +S++G    ++  +      +   G     VS+            ++
Sbjct: 473  TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532

Query: 980  NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039
            N     +   +  VS T    G+       +  E+   S+ G    T   +ST     T 
Sbjct: 533  NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 585

Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099
             ++    +  + T ++++ + +    +T+ A       T    +      AS   +    
Sbjct: 586  ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 645

Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156
            +  T+   +  + ST+         E  +   V + G+      E S  +T S +    T
Sbjct: 646  VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 703

Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208
            K S   SE    +T           G++T+T + +G+     S    +  S +T A++ G
Sbjct: 704  KVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 759

Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265
                 +ST+SS   +A+ +   S   ++S+    T + ST+ S    +F+++S+    S+
Sbjct: 760  SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817

Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317
            T        TA +  +    A S  TTT+      TTT+S+ GS +    T  S  + + 
Sbjct: 818  TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877

Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375
              G+  T    +    +  +  G  + ++ST  +   T S     T    +  S+     
Sbjct: 878  TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937

Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435
             + S+    S T   + +    GS TT      +  +   T G+ ++T + +   + +  
Sbjct: 938  TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 997

Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460
               +++    + GS    V S++GT
Sbjct: 998  IEGSETTTVSSTGSETTTV-STTGT 1021



 Score = 74.3 bits (181), Expect = 8e-13
 Identities = 188/936 (20%), Positives = 323/936 (34%), Gaps = 102/936 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTE--- 536
            T S + T +    E TT S +   ++   T  ++ T+ S+ GS M   S+   ++T    
Sbjct: 519  TGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST 578

Query: 537  --ANVLPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDC 593
              +     S+ G  T +V  A +   + S++  E   +S+    TT  ST   +T     
Sbjct: 579  EGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAST 638

Query: 594  EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSS----G 649
            EG      +    S   ++ + G +   I S     T T     +   +S+  S      
Sbjct: 639  EGS-ETTTVSTTDSETTMVSTTG-SERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696

Query: 650  IGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTT 707
            I   E+ K  ++    T       T+   I   +   S   TA   G ET   S  G  T
Sbjct: 697  ITGSETTKVSTTGSETT----TTSTEGSEITTASITGSETTTASTEGSETTTASTEGSET 752

Query: 708  LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767
             SAS TG          +      ++ ++      +  ET K  T   +  T  V +E++
Sbjct: 753  TSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT--VFTENS 810

Query: 768  ETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPA 827
            ET  AS+++   TT +    +         E +    +  +E     +  SE   +S  +
Sbjct: 811  ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTES 870

Query: 828  SSSSTVPVSLPSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886
            S ++T         ++G E      EGS   E      +   T   + E ++  T S   
Sbjct: 871  SETTTAT-------TIGSETTTASTEGS---ETTTTSTEGSETTTASTEGSEITTVS--- 917

Query: 887  GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS---SDSGSI 943
                ++ S  + AS+      ++S+ G   T  ST        G   I VS   S++ ++
Sbjct: 918  ----TTGSETTTASTEGSETTTASTEGSELTTVST-------TGSETITVSAEGSETTTV 966

Query: 944  NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVS 1003
              M      +   G     VS+            ++      +   +  VS T  +  ++
Sbjct: 967  TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTIT 1026

Query: 1004 NLGQEEKKEELPKSSSAGFSFGTG---VINSTPAPANTIVTSENKSSFNLGTIETKSASV 1060
            +    E        S     + TG      ST     T V++    +    T + ++ +V
Sbjct: 1027 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTV 1086

Query: 1061 APFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS---LV 1117
            +     T+ A       T    +      AS   +    +  T  +     T+ S    V
Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146

Query: 1118 FGKKADNEEPKC----QPVFSFGNSEQTK-----DENSSKSTFSFSMTKPSEKESEQPAK 1168
            F   ++              S   SE T       E ++ ST     T  S   SE    
Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTA 1206

Query: 1169 ATFAF--------GAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSN 1220
            +T           G++TST +  G+       + + ++ +ST               +S 
Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAST---------------ASL 1251

Query: 1221 PPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGAS 1280
             P AT + G  +  VS +A G TA S+T  S  F        T +T  ++ P    P + 
Sbjct: 1252 EPTATSLTGSETTTVSITASGATAASTTVSSTTF------VLTKATDVSIQPITNTPMSG 1305

Query: 1281 SNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPG 1340
            +  T     G   T +SS   +  +  T  +A    P    N +     + GAS      
Sbjct: 1306 TRTT-----GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAH 1360

Query: 1341 FGSISSSTALFPTGS---QPAPPTFG--TVSSSSQP 1371
                ++ +   PT S   +  P + G  TVS S  P
Sbjct: 1361 GVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTP 1396



 Score = 54.7 bits (130), Expect = 7e-07
 Identities = 165/869 (18%), Positives = 302/869 (34%), Gaps = 104/869 (11%)

Query: 476  SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535
            S   T S   T + +S E TT+S     ++   T   + T  S+TGS     S+   ++T
Sbjct: 615  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 536  -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586
                   E  V    S   T S+  ++T ++S  GS +T     S+    +TT + T   
Sbjct: 675  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---TTSTEGSEITTASITG-S 730

Query: 587  KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646
            +T     EG         EGS      + G      ++  A  T++   + +     +  
Sbjct: 731  ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 784

Query: 647  SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706
            +S IG   +  + +S +  T   +N  ++    +  A++ +   TA    I       +T
Sbjct: 785  ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 707  TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766
            T + S  G         G+         ++      +  ET    T  + + T T  +E 
Sbjct: 843  TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 900

Query: 767  AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
            +ET TAS+    +TT            + +        S    +    S    +  ++V 
Sbjct: 901  SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 947

Query: 827  ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886
             + S T+ VS               EGS    +  + ++  +      E+    T     
Sbjct: 948  TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 887  GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946
               +   S  +  SS+     + S++G   T+TST     G +        S++ ++   
Sbjct: 994  TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAV--- 1046

Query: 947  SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006
                          +   SE+     +          G  +  ++   L       S  G
Sbjct: 1047 --------------YTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066
                     ++++    + TG   +T +   +  T+ + +S    T  T  + +      
Sbjct: 1093 TTTASTAGSETTTV---YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149

Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126
             SE        T    + G+    S  + S      TE  +    T+T+   G +     
Sbjct: 1150 VSE--------TTTVSTIGSEATTSSAAGSEATTTSTEGSE----TTTASTAGSETTTAS 1197

Query: 1127 PKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAA 1186
                   +   S     E ++  T     + PS   SE      F  G++T T A   + 
Sbjct: 1198 TAGSETTTASTS---GSETNTACTTGSETSTPSSAGSE--TNTAFIIGSET-TIASTASL 1251

Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF------ 1240
            +P  + L  + S ++T + +A G    S+T SS   V T     S  P++++        
Sbjct: 1252 EPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1309

Query: 1241 GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTSS 1298
            G    +S+S ++    D   +  S T   +     G G S+   ++TTS  G   TT S+
Sbjct: 1310 GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369

Query: 1299 SAGSSFVF-GTGPSAPSASPAFGANQTPT 1326
               +S  F  TGP +   +     + TPT
Sbjct: 1370 REPTSSTFQETGPVSMGTN-TVSMSHTPT 1397



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 50/197 (25%), Positives = 80/197 (40%), Gaps = 29/197 (14%)

Query: 1277 PGASSNNTTTSGFGF---------GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327
            P A SN TT S  G            TTT+S+AGS     T PS   +     +      
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET---TTPSPTGSQTTIVSISGSEI 65

Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ-SAFGSG 1386
              +  A   N     + S +T     GS+    T G  S ++   + G + +  SA GS 
Sbjct: 66   TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG--SETTTVSITGTETTMVSAMGSE 123

Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446
            TT NS+++    S TT  +   +  + V T G+ ++T   +           +++ AA T
Sbjct: 124  TTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYTAD----------SETTAAST 169

Query: 1447 VGSNGKNVFSSSGTSFS 1463
             GS    VF++   + +
Sbjct: 170  TGSEMTTVFTAGSETIT 186


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 207/1055 (19%), Positives = 376/1055 (35%), Gaps = 112/1055 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            TSS     + +  E TT S     ++ A T   + T+ S+TGS M    + +  +    +
Sbjct: 130  TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM----TTVFTAGSETI 185

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599
             P ++   T +V  A +   + S++  E   +S+AH  TT  ST   +T      G    
Sbjct: 186  TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 600  AE------------------ILKEGSVLDILKSPGFASPKIDSVAAQPTATS-------- 633
                                   E S      + GF +    +  ++PT  S        
Sbjct: 246  VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTM 305

Query: 634  -----PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-- 686
                 P        SS  ++    G      S+   +T  +    ++    +   ++   
Sbjct: 306  ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365

Query: 687  -----SPRDTAKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEA 739
                 S   TA   G ET   S  G    + S TG       +  +    TC   ++  A
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 740  IKCVACETPKPGT------------------CVKRALTLTVVSESAETMTA-SSSSCTVT 780
            +     ET    T                    + + T TV +  +ET TA ++ S T T
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485

Query: 781  TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS--- 836
                G        IGS        S    +   VS   SE    S   S ++TV  +   
Sbjct: 486  ASNTGLETTTVFTIGS---DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSE 542

Query: 837  LPSGGSLGLE-KFKKPEGS-------WDCELCLVQNKADSTKCLACESAKPGTKSGFKGF 888
              +  + GLE      EGS          E      +   T   +   ++  T S     
Sbjct: 543  TTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSE 602

Query: 889  DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE 948
            +T++S+++S  +S+   G  ++++  + + T+T + + G +        S++  ++    
Sbjct: 603  NTTASTADSETTSASTTGSETTTASTTSSETTTASTE-GSETTTVSTTDSETTMVSTTGS 661

Query: 949  GFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQE 1008
                +   G     VS+      V  +         ++   +  VS T    G       
Sbjct: 662  ERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTT----GSETTTTS 716

Query: 1009 EKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTS 1068
             +  E+  +S  G    T     +     +   SE  S+   G+  T +++ +  T   S
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 1069 EAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPK 1128
                E   A+  G     V  AS    +VF      E  +  + ST+            +
Sbjct: 777  IMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAGSE 831

Query: 1129 CQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTADQG 1184
              P  + G+  +  T  E S  +T S   S T  +  ES +   AT   G++T+T + +G
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTASTEG 890

Query: 1185 AAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTA 1244
            +     S    +  S +T A++ G  I   ST+ S    A+    +++   +  +   T 
Sbjct: 891  SETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTV 946

Query: 1245 ESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-- 1302
             ++ S+++  S +    TT +T  + T      G+ +   +T+G     TTT+S  GS  
Sbjct: 947  STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGSET 1003

Query: 1303 SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF 1362
            + V  TG    + S   G   T T  +    +     G    S +TA++ TGS+    T 
Sbjct: 1004 TTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE----TT 1054

Query: 1363 GTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS 1422
             T +  S+        S++   S     +++    GS TT  +   +  + V+  G+ ++
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114

Query: 1423 TPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457
            T +     + +     +++  A T GS    VF++
Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 191/1007 (18%), Positives = 371/1007 (36%), Gaps = 107/1007 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T S   T +    E +T S +   ++ A T   + T+ S+ GS     S+   ++T  ++
Sbjct: 349  TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598
                +     +    + +E++  S+T+ E   +S+     T+ ST+  +T     EG   
Sbjct: 409  TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 462

Query: 599  PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658
               +   GS      + G  +    +   + T     V+T   I S +++    G    A
Sbjct: 463  TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 515

Query: 659  GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716
             S+   +   +  + ++N  ++   ++ +   T   TG+ET   S  G    + S TG  
Sbjct: 516  VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 572

Query: 717  DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776
                   G+         ++   +     E     T      T +  +  +ET TAS++S
Sbjct: 573  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 630

Query: 777  CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836
               TT +           GS   +V   + ++E     +  SE+  +S   S ++TV  +
Sbjct: 631  SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 679

Query: 837  LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896
                   G E     EGS    + +  ++         E+    T+       + + S  
Sbjct: 680  -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 897  SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956
            + AS+      ++S+ G   T  ST     G +       SS++   + M      +  I
Sbjct: 733  TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 788

Query: 957  GDFKFGVSS-ESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELP 1015
            G     VS+  SK   V  ++         +S  +   +        S  G E       
Sbjct: 789  GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT--- 845

Query: 1016 KSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEM 1075
             +S+ G    T     +     +  +SE  ++  +G+  T +++    T  TS    E  
Sbjct: 846  -TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 1076 PATKGGFSFGNVEPASLPSASVFVLGR------TEEKQQEPVTST-SLVFGKKADNEEPK 1128
             A+  G     V      + +    G       TE  +   V++T S      A+  E  
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 1129 CQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATF--AFGAQTSTTADQGAA 1186
               V + G+   T     S++T   +    +   S + ++ T   + G++T+T +  G  
Sbjct: 965  T--VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1022

Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246
              + S    +  S +T  T+AG       T+ S     +    +++   ++ +   TA +
Sbjct: 1023 TTITS----TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078

Query: 1247 STSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVF 1306
            +  ++   S      TT+ST  + T  V+  G  S  TT S  G  ATT S+++      
Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSETTTVYITG--SKTTTASTEGSEATTVSTTS------ 1130

Query: 1307 GTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVS 1366
                S  + +   G+  T                F ++S +T +   GS+    +     
Sbjct: 1131 ----SETTTASTTGSEMTTV--------------FTTVSETTTVSTIGSEATTSSAAGSE 1172

Query: 1367 SSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAA 1426
            +++      +  + S  GS TT  S++    GS TT  + + +  +   T G+ +STP++
Sbjct: 1173 ATTTSTEGSETTTASTAGSETTTASTA----GSETTTASTSGSETNTACTTGSETSTPSS 1228

Query: 1427 SAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSS----GTSFSGRKIKT 1469
            +           +++  AF +GS      ++S     TS +G +  T
Sbjct: 1229 AG----------SETNTAFIIGSESTIASTASLEPTATSLTGSETTT 1265



 Score = 85.1 bits (209), Expect = 5e-16
 Identities = 157/800 (19%), Positives = 285/800 (35%), Gaps = 65/800 (8%)

Query: 691  TAKQTGIETP-NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749
            TA   G ET  + +G  T + S TG        +G+         ++         ET  
Sbjct: 87   TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146

Query: 750  PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809
              T      T T  +  +ET  AS++   +TT      +         E +   VS    
Sbjct: 147  VSTVGSE--TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTT--VSTAGS 202

Query: 810  DNKCVSCMSEKPGSSVPASSSSTVPVSLPSG----GSLGLEKFKKPEGSWDCELCLVQNK 865
            +   VS    +  ++  A S +T   ++ S      + G E      GS   E      +
Sbjct: 203  ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---ETTAASTE 259

Query: 866  ADSTKCLACESAKPGTKSGFKGFDTSSSSSNSA----ASSSFKFGVSSSSSGPSQTLTST 921
               T     E +K  T S   GF+T+++S+  +    AS+       +S+ GP  T  ST
Sbjct: 260  DSETNTAFTEDSKTTTAST-TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVST 318

Query: 922  GN------FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975
             +      F  G +      V S++ +++        +  +G      S+          
Sbjct: 319  ASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTAST 378

Query: 976  SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035
              ++          +  VS T  +    ++   E      + S       T    +T + 
Sbjct: 379  EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438

Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095
              + +T  + S     T  T+ +     T   SE K     A   G          L + 
Sbjct: 439  EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT----AYTTGSETTTASNTGLETT 494

Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK-----DENSSKST 1150
            +VF +G          + T+ V    ++          S   SE T       E ++ ST
Sbjct: 495  TVFTIGSDTTTASTEGSETTAVSATGSE------MTTVSTEGSENTTVSTTGSETTTVST 548

Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210
                 T  S + SE    +T   GA+T+T + +G              S +T A++AG  
Sbjct: 549  TGLETTTTSTEGSEMTTVSTT--GAETTTDSTEG--------------SGTTAASTAGSE 592

Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV 1270
                ST+ S    A+    ++++  ++ +   TA +++S++   S +    TT ST  + 
Sbjct: 593  TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652

Query: 1271 TPFVFGPGA--------SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGAN 1322
            T  V   G+         S  TT S  G   T ++  +G++ V  TG      S   G+ 
Sbjct: 653  TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-GSE 711

Query: 1323 QTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380
             T T  +    +  +  G  + ++ST  +   T S     T    ++ S+        S+
Sbjct: 712  TTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771

Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440
            +   S     ++ A   GS TT  +  ++  + VFT  + ++  + +A  + +     ++
Sbjct: 772  TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 1441 SPAAFTVGSNGKNVFSSSGT 1460
            +  A T GS      S+ G+
Sbjct: 832  TIPASTAGSETTTTTSTEGS 851



 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 193/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%)

Query: 478  PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537
            P   S+  T + +  E TT       ++ A T   + T+PS TGS     S    + T  
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 68

Query: 538  NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582
            +     +   + +     TA ++GS +T+               E  + S+    TT NS
Sbjct: 69   STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS 128

Query: 583  TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642
            T   +T      G         E + +  + S    +   DS     + T   + T    
Sbjct: 129  TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 643  SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702
             S + +    G      S+   +T  +    ++    +   ++ +   T      +    
Sbjct: 181  GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 240

Query: 703  SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758
              +TT+S +G+           T D +T       +K         ET    T   +  +
Sbjct: 241  GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295

Query: 759  TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810
              T+ SE+        ET   S++S  VTT      +  +   +GS       VS    +
Sbjct: 296  ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 352

Query: 811  NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869
                S M SE    S   S ++T         +   E  +    S         +  DS 
Sbjct: 353  TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412

Query: 870  KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923
                C      T      F+T+++S+       A++S  +   +S+    + T+T+ G+ 
Sbjct: 413  TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 472

Query: 924  FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979
             K     G +   +S++G    ++  +      +   G     VS+            ++
Sbjct: 473  TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532

Query: 980  NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039
            N     +   +  VS T    G+       +  E+   S+ G    T   +ST     T 
Sbjct: 533  NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 585

Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099
             ++    +  + T ++++ + +    +T+ A       T    +      AS   +    
Sbjct: 586  ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 645

Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156
            +  T+   +  + ST+         E  +   V + G+      E S  +T S +    T
Sbjct: 646  VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 703

Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208
            K S   SE    +T           G++T+T + +G+     S    +  S +T A++ G
Sbjct: 704  KVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 759

Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265
                 +ST+SS   +A+ +   S   ++S+    T + ST+ S    +F+++S+    S+
Sbjct: 760  SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817

Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317
            T        TA +  +    A S  TTT+      TTT+S+ GS +    T  S  + + 
Sbjct: 818  TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877

Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375
              G+  T    +    +  +  G  + ++ST  +   T S     T    +  S+     
Sbjct: 878  TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937

Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435
             + S+    S T   + +    GS TT      +  +   T G+ ++T + +   + +  
Sbjct: 938  TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 997

Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460
               +++    + GS    V S++GT
Sbjct: 998  IEGSETTTVSSTGSETTTV-STTGT 1021



 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 189/936 (20%), Positives = 323/936 (34%), Gaps = 102/936 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTE--- 536
            T S + T +    E TT S +   ++   T  ++ T+ S+ GS M   S+   ++T    
Sbjct: 519  TGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST 578

Query: 537  --ANVLPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDC 593
              +     S+ G  T +V  A +   + S++  E   +S+    TT  ST   +T     
Sbjct: 579  EGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAST 638

Query: 594  EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSS----G 649
            EG      +    S   ++ + G +   I S     T T     +   +S+  S      
Sbjct: 639  EGS-ETTTVSTTDSETTMVSTTG-SERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696

Query: 650  IGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTT 707
            I   E+ K  ++    T       T+   I   +   S   TA   G ET   S  G  T
Sbjct: 697  ITGSETTKVSTTGSETT----TTSTEGSEITTASITGSETTTASTEGSETTTASTEGSET 752

Query: 708  LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767
             SAS TG          +      ++ ++      +  ET K  T   +  T  V +E++
Sbjct: 753  TSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT--VFTENS 810

Query: 768  ETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPA 827
            ET  AS+++   TT +    +         E +    +  +E     +  SE   +S  +
Sbjct: 811  ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTES 870

Query: 828  SSSSTVPVSLPSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886
            S ++T         ++G E      EGS   E      +   T   + E ++  T S   
Sbjct: 871  SETTTAT-------TIGSETTTASTEGS---ETTTTSTEGSETTTASTEGSEITTVS--- 917

Query: 887  GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS---SDSGSI 943
                ++ S  + AS+      ++S+ G   T  ST        G   I VS   S++ ++
Sbjct: 918  ----TTGSETTTASTEGSETTTASTEGSELTTVST-------TGSETITVSAEGSETTTV 966

Query: 944  NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVS 1003
              M      +   G     VS+            ++      +   +  VS T  +  ++
Sbjct: 967  TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTIT 1026

Query: 1004 NLGQEEKKEELPKSSSAGFSFGTG---VINSTPAPANTIVTSENKSSFNLGTIETKSASV 1060
            +    E        S     + TG      ST     T V++    +    T + ++ +V
Sbjct: 1027 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTV 1086

Query: 1061 APFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS---LV 1117
            +     T+ A       T    +      AS   +    +  T  +     T+ S    V
Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146

Query: 1118 FGKKADNEEPKC----QPVFSFGNSEQTK-----DENSSKSTFSFSMTKPSEKESEQPAK 1168
            F   ++              S   SE T       E ++ ST     T  S   SE    
Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTA 1206

Query: 1169 ATFAF--------GAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSN 1220
            +T           G++TST +  G+       + + S+ +ST               +S 
Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIAST---------------ASL 1251

Query: 1221 PPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGAS 1280
             P AT + G  +  VS +A G TA S+T  S  F        T +T  ++ P    P + 
Sbjct: 1252 EPTATSLTGSETTTVSITASGATAASTTVSSTTF------VLTKATDVSIQPITNTPMSG 1305

Query: 1281 SNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPG 1340
            +  T     G   T +SS   +  +  T  +A    P    N +     + GAS      
Sbjct: 1306 TRTT-----GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAH 1360

Query: 1341 FGSISSSTALFPTGS---QPAPPTFG--TVSSSSQP 1371
                ++ +   PT S   +  P + G  TVS S  P
Sbjct: 1361 GVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTP 1396



 Score = 54.3 bits (129), Expect = 9e-07
 Identities = 165/869 (18%), Positives = 302/869 (34%), Gaps = 104/869 (11%)

Query: 476  SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535
            S   T S   T + +S E TT+S     ++   T   + T  S+TGS     S+   ++T
Sbjct: 615  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 536  -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586
                   E  V    S   T S+  ++T ++S  GS +T     S+    +TT + T   
Sbjct: 675  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---TTSTEGSEITTASITG-S 730

Query: 587  KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646
            +T     EG         EGS      + G      ++  A  T++   + +     +  
Sbjct: 731  ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 784

Query: 647  SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706
            +S IG   +  + +S +  T   +N  ++    +  A++ +   TA    I       +T
Sbjct: 785  ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 707  TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766
            T + S  G         G+         ++      +  ET    T  + + T T  +E 
Sbjct: 843  TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 900

Query: 767  AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
            +ET TAS+    +TT            + +        S    +    S    +  ++V 
Sbjct: 901  SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 947

Query: 827  ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886
             + S T+ VS               EGS    +  + ++  +      E+    T     
Sbjct: 948  TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 887  GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946
               +   S  +  SS+     + S++G   T+TST     G +        S++ ++   
Sbjct: 994  TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAV--- 1046

Query: 947  SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006
                          +   SE+     +          G  +  ++   L       S  G
Sbjct: 1047 --------------YTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066
                     ++++    + TG   +T +   +  T+ + +S    T  T  + +      
Sbjct: 1093 TTTASTAGSETTTV---YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149

Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126
             SE        T    + G+    S  + S      TE  +    T+T+   G +     
Sbjct: 1150 VSE--------TTTVSTIGSEATTSSAAGSEATTTSTEGSE----TTTASTAGSETTTAS 1197

Query: 1127 PKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAA 1186
                   +   S     E ++  T     + PS   SE      F  G++ ST A   + 
Sbjct: 1198 TAGSETTTASTS---GSETNTACTTGSETSTPSSAGSE--TNTAFIIGSE-STIASTASL 1251

Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF------ 1240
            +P  + L  + S ++T + +A G    S+T SS   V T     S  P++++        
Sbjct: 1252 EPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1309

Query: 1241 GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTSS 1298
            G    +S+S ++    D   +  S T   +     G G S+   ++TTS  G   TT S+
Sbjct: 1310 GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369

Query: 1299 SAGSSFVF-GTGPSAPSASPAFGANQTPT 1326
               +S  F  TGP +   +     + TPT
Sbjct: 1370 REPTSSTFQETGPVSMGTN-TVSMSHTPT 1397



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 50/197 (25%), Positives = 80/197 (40%), Gaps = 29/197 (14%)

Query: 1277 PGASSNNTTTSGFGF---------GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327
            P A SN TT S  G            TTT+S+AGS     T PS   +     +      
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET---TTPSPTGSQTTIVSISGSEI 65

Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ-SAFGSG 1386
              +  A   N     + S +T     GS+    T G  S ++   + G + +  SA GS 
Sbjct: 66   TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG--SETTTVSITGTETTMVSAMGSE 123

Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446
            TT NS+++    S TT  +   +  + V T G+ ++T   +           +++ AA T
Sbjct: 124  TTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYTAD----------SETTAAST 169

Query: 1447 VGSNGKNVFSSSGTSFS 1463
             GS    VF++   + +
Sbjct: 170  TGSEMTTVFTAGSETIT 186


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 207/1055 (19%), Positives = 376/1055 (35%), Gaps = 112/1055 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            TSS     + +  E TT S     ++ A T   + T+ S+TGS M    + +  +    +
Sbjct: 151  TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM----TTVFTAGSETI 206

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599
             P ++   T +V  A +   + S++  E   +S+AH  TT  ST   +T      G    
Sbjct: 207  TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 266

Query: 600  AE------------------ILKEGSVLDILKSPGFASPKIDSVAAQPTATS-------- 633
                                   E S      + GF +    +  ++PT  S        
Sbjct: 267  VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTM 326

Query: 634  -----PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-- 686
                 P        SS  ++    G      S+   +T  +    ++    +   ++   
Sbjct: 327  ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 386

Query: 687  -----SPRDTAKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEA 739
                 S   TA   G ET   S  G    + S TG       +  +    TC   ++  A
Sbjct: 387  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 446

Query: 740  IKCVACETPKPGT------------------CVKRALTLTVVSESAETMTA-SSSSCTVT 780
            +     ET    T                    + + T TV +  +ET TA ++ S T T
Sbjct: 447  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 506

Query: 781  TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS--- 836
                G        IGS        S    +   VS   SE    S   S ++TV  +   
Sbjct: 507  ASNTGLETTTVFTIGS---DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSE 563

Query: 837  LPSGGSLGLE-KFKKPEGS-------WDCELCLVQNKADSTKCLACESAKPGTKSGFKGF 888
              +  + GLE      EGS          E      +   T   +   ++  T S     
Sbjct: 564  TTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSE 623

Query: 889  DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE 948
            +T++S+++S  +S+   G  ++++  + + T+T + + G +        S++  ++    
Sbjct: 624  NTTASTADSETTSASTTGSETTTASTTSSETTTASTE-GSETTTVSTTDSETTMVSTTGS 682

Query: 949  GFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQE 1008
                +   G     VS+      V  +         ++   +  VS T    G       
Sbjct: 683  ERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTT----GSETTTTS 737

Query: 1009 EKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTS 1068
             +  E+  +S  G    T     +     +   SE  S+   G+  T +++ +  T   S
Sbjct: 738  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 797

Query: 1069 EAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPK 1128
                E   A+  G     V  AS    +VF      E  +  + ST+            +
Sbjct: 798  IMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAGSE 852

Query: 1129 CQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTADQG 1184
              P  + G+  +  T  E S  +T S   S T  +  ES +   AT   G++T+T + +G
Sbjct: 853  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTASTEG 911

Query: 1185 AAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTA 1244
            +     S    +  S +T A++ G  I   ST+ S    A+    +++   +  +   T 
Sbjct: 912  SETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTV 967

Query: 1245 ESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-- 1302
             ++ S+++  S +    TT +T  + T      G+ +   +T+G     TTT+S  GS  
Sbjct: 968  STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGSET 1024

Query: 1303 SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF 1362
            + V  TG    + S   G   T T  +    +     G    S +TA++ TGS+    T 
Sbjct: 1025 TTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE----TT 1075

Query: 1363 GTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS 1422
             T +  S+        S++   S     +++    GS TT  +   +  + V+  G+ ++
Sbjct: 1076 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1135

Query: 1423 TPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457
            T +     + +     +++  A T GS    VF++
Sbjct: 1136 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1170



 Score = 95.1 bits (235), Expect = 4e-19
 Identities = 206/1019 (20%), Positives = 385/1019 (37%), Gaps = 104/1019 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T++S   F  ++   T S P+  ++  + T       P +T           V +  +  
Sbjct: 295  TTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET 354

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599
            +  S++G   +     T   +GS +T   I+ S     T+ +ST   +T     EG    
Sbjct: 355  IRASTVGSETT-----TVSTTGSETTTASIMGSE----TSTDSTTGSETTTASTEGS-ET 404

Query: 600  AEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF-----SSSGIGFGE 654
                 EGS    + + G  +  +    ++ T T        A+S+      ++S  G   
Sbjct: 405  TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 464

Query: 655  SLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-----SPRDTAKQTGIETPN--KSGKTT 707
            ++ + S  +  T   +   T     A    K      S   TA  TG+ET      G  T
Sbjct: 465  TIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDT 524

Query: 708  LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767
             +AS  G         G+         ++   +     ET    T      T T  +E +
Sbjct: 525  TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLE--TTTTSTEGS 582

Query: 768  ETMTASSSSCTVTT-GTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
            E  T S++    TT  T G G       GS   +V     ++E+    +  SE   +S  
Sbjct: 583  EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA--DSENTTASTADSETTSASTT 640

Query: 827  ASSSSTVPVSLPSGGSLGLEKFKKPEGSW-DCELCLVQNKADSTKCLACESAKPGTKSGF 885
             S ++T   +     +   E  +    S  D E  +V          + E ++  T S  
Sbjct: 641  GSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSA- 699

Query: 886  KGFDTSSSSSNSAASSSFKFGVSS---SSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGS 942
             G +T+ S+  S  ++    G  +   S++G   T TST         G +I  +S +GS
Sbjct: 700  TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTE--------GSEITTASITGS 751

Query: 943  --INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQF 1000
                  +EG + +    +     S+ +   E    S   + +  ++S + +  ++     
Sbjct: 752  ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSS-ETTMASIMGSETTMA---- 806

Query: 1001 GVSNLGQEEKKEELPKSSSAGF---SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS 1057
              S +G E  K     S        +  T + ++T +   T+ T+ ++      TI   +
Sbjct: 807  --STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE------TIPAST 858

Query: 1058 ASVAPFTCKTSEAKKEEMPATKGG-FSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSL 1116
            A     T  ++E  +    +T+G   +  + E +   +A+      T    +   T+T+ 
Sbjct: 859  AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 918

Query: 1117 VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQ 1176
              G +      +   + +      T  E ++ ST     T  S + SE    +T   G++
Sbjct: 919  TEGSETTTASTEGSEITTVST---TGSETTTASTEGSETTTASTEGSELTTVSTT--GSE 973

Query: 1177 TSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVS 1236
            T T + +G+     + +     S +T A++AG      ST+ S    A+ + G  +  VS
Sbjct: 974  TITVSAEGSETTTVTTMG----SETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVS 1028

Query: 1237 SSAFGNTAESST-SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATT 1295
            S+    T  S+T +++ + S +    TT +T  + T  V+  G+ +  T+T G     TT
Sbjct: 1029 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG---SETT 1085

Query: 1296 TSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGS 1355
            T S+ GS             + A  A+   T   + G+        GS   +T ++ TGS
Sbjct: 1086 TVSTTGSE-----------TTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGS 1132

Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415
            +       T ++S++        S++   S T+  +++A   GS  T    T +  + V 
Sbjct: 1133 K-------TTTASTEG-------SEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVS 1178

Query: 1416 TFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSG----TSFSGRKIKTA 1470
            T G+ ++T +A+   + +     +++  A T GS      ++       S SG +  TA
Sbjct: 1179 TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTA 1237



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 173/891 (19%), Positives = 331/891 (37%), Gaps = 89/891 (9%)

Query: 630  TATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLS-P 688
            TA S V+ T  ++SS ++     G +    S+   +T  +  K ++    +   ++ + P
Sbjct: 11   TADSKVI-TASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTP 69

Query: 689  RDTAKQTGIETPNKSGKTTLSASGT--------GFGDKFKPVIGTWDCDTCLVQNKPEAI 740
              T  QT I + + S  TT S +G+        G G     + G+ +       ++   +
Sbjct: 70   SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGS-ESTISTAGSETTTV 128

Query: 741  KCVACETPKPGTCVKRALT-LTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWEC 799
                 ET           T  T  SE+  T TA S + TV+T     G +      +   
Sbjct: 129  SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVST----VGSETTTAYTADSE 184

Query: 800  SVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCEL 859
            +    +  +E     +  SE    S   S ++TV  +     ++         GS     
Sbjct: 185  TTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTT------GSETTTA 238

Query: 860  CLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLT 919
                ++  +   +  E+ K  T        T+ S + +A++   +   + +    + T +
Sbjct: 239  STAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAS 298

Query: 920  STGNFKFGDQGGFKIGVSSDSGS----INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975
            +TG         F+   +S +GS     + M      +  IG     VS+ S        
Sbjct: 299  TTG---------FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFA 349

Query: 976  SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035
            + ++  +       +  VS T  +   +++   E   +    S+ G    T    ST   
Sbjct: 350  AGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTD----STTGSETTTA---STEGS 402

Query: 1036 ANTIVTSENKSSFNLGTI--ETKSASVAPFTCKTSEAKKEEMPA-------TKGGFSFGN 1086
              T  ++E   +  + T   ET + S+      T+  +  EM A       T    + G+
Sbjct: 403  ETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGS 462

Query: 1087 VEPASLPSASVFVLGRTEEKQQEPVTS------TSLVFGKK---ADNEEPKCQPVFSFGN 1137
                +  S S      TE  +   VT+      T+   G +   A N   +   VF+ G+
Sbjct: 463  EITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGS 522

Query: 1138 SEQTKDENSSKSTF----SFSMTKPSEKESEQPAKATFAF--------GAQTSTTADQGA 1185
               T     S++T        MT  S + SE    +T           G +T+TT+ +G+
Sbjct: 523  DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGS 582

Query: 1186 AKPVFSFL------NNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSA 1239
                 S        +++  S +T A++AG      ST+ S    A+    ++++  ++ +
Sbjct: 583  EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGS 642

Query: 1240 FGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGA--------SSNNTTTSGFGF 1291
               TA +++S++   S +    TT ST  + T  V   G+         S  TT S  G 
Sbjct: 643  ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 702

Query: 1292 GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSST--A 1349
              T ++  +G++ V  TG      S   G+  T T  +    +  +  G  + ++ST  +
Sbjct: 703  ETTVSTEGSGTTTVSITGSETTKVSTT-GSETTTTSTEGSEITTASITGSETTTASTEGS 761

Query: 1350 LFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNN 1409
               T S     T    ++ S+        S++   S     ++ A   GS TT  +  ++
Sbjct: 762  ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 821

Query: 1410 SPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGT 1460
              + VFT  + ++  + +A  + +     +++  A T GS      S+ G+
Sbjct: 822  KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 872



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 186/973 (19%), Positives = 359/973 (36%), Gaps = 75/973 (7%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T S   T +    E +T S +   ++ A T   + T+ S+ GS     S+   ++T  ++
Sbjct: 370  TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 429

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598
                +     +    + +E++  S+T+ E   +S+     T+ ST+  +T     EG   
Sbjct: 430  TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 483

Query: 599  PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658
               +   GS      + G  +    +   + T     V+T   I S +++    G    A
Sbjct: 484  TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 536

Query: 659  GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716
             S+   +   +  + ++N  ++   ++ +   T   TG+ET   S  G    + S TG  
Sbjct: 537  VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 593

Query: 717  DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776
                   G+         ++   +     E     T      T +  +  +ET TAS++S
Sbjct: 594  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 651

Query: 777  CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836
               TT +           GS   +V   + ++E     +  SE+  +S   S ++TV  +
Sbjct: 652  SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 700

Query: 837  LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896
                   G E     EGS    + +  ++         E+    T+       + + S  
Sbjct: 701  -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 753

Query: 897  SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956
            + AS+      ++S+ G   T  ST     G +       SS++   + M      +  I
Sbjct: 754  TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 809

Query: 957  GDFKFGVSS-ESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELP 1015
            G     VS+  SK   V  ++         +S  +   +        S  G E       
Sbjct: 810  GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT--- 866

Query: 1016 KSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEM 1075
             +S+ G    T     +     +  +SE  ++  +G+  T +++    T  TS    E  
Sbjct: 867  -TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 925

Query: 1076 PATKGGFSFGNVEPASLPSASVFVLGR------TEEKQQEPVTST-SLVFGKKADNEEPK 1128
             A+  G     V      + +    G       TE  +   V++T S      A+  E  
Sbjct: 926  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 985

Query: 1129 CQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATF--AFGAQTSTTADQGAA 1186
               V + G+   T     S++T   +    +   S + ++ T   + G++T+T +  G  
Sbjct: 986  T--VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1043

Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246
              + S    +  S +T  T+AG       T+ S     +    +++   ++ +   TA +
Sbjct: 1044 TTITS----TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1099

Query: 1247 STSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSG-------FGFGATTTSSS 1299
            +  ++   S      TT+ST  + T  V+  G+ +   +T G            TTT+S+
Sbjct: 1100 ADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAST 1159

Query: 1300 AGSSF--VFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTA--LFPTGS 1355
             GS    VF T     + S   G+  T +      A+  +  G  + ++STA     T S
Sbjct: 1160 TGSEMTTVFTTVSETTTVS-TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1218

Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415
                 T    +S S+        S+++  S     +++AF  GS TT  +  +  P+   
Sbjct: 1219 TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATS 1278

Query: 1416 TFGANSSTPAASA 1428
              G+ ++T + +A
Sbjct: 1279 LTGSETTTVSITA 1291



 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 194/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%)

Query: 478  PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537
            P   S+  T + +  E TT       ++ A T   + T+PS TGS     S    + T  
Sbjct: 30   PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 89

Query: 538  NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582
            +     +   + +     TA ++GS ST+               E  + S+    TT NS
Sbjct: 90   STAGSENTTVSSAGSGTTTASMAGSESTISTAGSETTTVSITGTETTMVSAMGSETTTNS 149

Query: 583  TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642
            T   +T      G         E + +  + S    +   DS     + T   + T    
Sbjct: 150  TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 201

Query: 643  SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702
             S + +    G      S+   +T  +    ++    +   ++ +   T      +    
Sbjct: 202  GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 261

Query: 703  SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758
              +TT+S +G+           T D +T       +K         ET    T   +  +
Sbjct: 262  GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 316

Query: 759  TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810
              T+ SE+        ET   S++S  VTT      +  +   +GS       VS    +
Sbjct: 317  ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 373

Query: 811  NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869
                S M SE    S   S ++T         +   E  +    S         +  DS 
Sbjct: 374  TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 433

Query: 870  KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923
                C      T      F+T+++S+       A++S  +   +S+    + T+T+ G+ 
Sbjct: 434  TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 493

Query: 924  FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979
             K     G +   +S++G    ++  +      +   G     VS+            ++
Sbjct: 494  TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 553

Query: 980  NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039
            N     +   +  VS T    G+       +  E+   S+ G    T   +ST     T 
Sbjct: 554  NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 606

Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099
             ++    +  + T ++++ + +    +T+ A       T    +      AS   +    
Sbjct: 607  ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 666

Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156
            +  T+   +  + ST+         E  +   V + G+      E S  +T S +    T
Sbjct: 667  VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 724

Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208
            K S   SE    +T           G++T+T + +G+     S    +  S +T A++ G
Sbjct: 725  KVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 780

Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265
                 +ST+SS   +A+ +   S   ++S+    T + ST+ S    +F+++S+    S+
Sbjct: 781  SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 838

Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317
            T        TA +  +    A S  TTT+      TTT+S+ GS +    T  S  + + 
Sbjct: 839  TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 898

Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375
              G+  T    +    +  +  G  + ++ST  +   T S     T    +  S+     
Sbjct: 899  TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 958

Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435
             + S+    S T   + +    GS TT      +  +   T G+ ++T + +   + +  
Sbjct: 959  TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 1018

Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460
               +++    + GS    V S++GT
Sbjct: 1019 IEGSETTTVSSTGSETTTV-STTGT 1042



 Score = 74.3 bits (181), Expect = 8e-13
 Identities = 188/936 (20%), Positives = 323/936 (34%), Gaps = 102/936 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTE--- 536
            T S + T +    E TT S +   ++   T  ++ T+ S+ GS M   S+   ++T    
Sbjct: 540  TGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST 599

Query: 537  --ANVLPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDC 593
              +     S+ G  T +V  A +   + S++  E   +S+    TT  ST   +T     
Sbjct: 600  EGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAST 659

Query: 594  EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSS----G 649
            EG      +    S   ++ + G +   I S     T T     +   +S+  S      
Sbjct: 660  EGS-ETTTVSTTDSETTMVSTTG-SERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 717

Query: 650  IGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTT 707
            I   E+ K  ++    T       T+   I   +   S   TA   G ET   S  G  T
Sbjct: 718  ITGSETTKVSTTGSETT----TTSTEGSEITTASITGSETTTASTEGSETTTASTEGSET 773

Query: 708  LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767
             SAS TG          +      ++ ++      +  ET K  T   +  T  V +E++
Sbjct: 774  TSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT--VFTENS 831

Query: 768  ETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPA 827
            ET  AS+++   TT +    +         E +    +  +E     +  SE   +S  +
Sbjct: 832  ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTES 891

Query: 828  SSSSTVPVSLPSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886
            S ++T         ++G E      EGS   E      +   T   + E ++  T S   
Sbjct: 892  SETTTAT-------TIGSETTTASTEGS---ETTTTSTEGSETTTASTEGSEITTVS--- 938

Query: 887  GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS---SDSGSI 943
                ++ S  + AS+      ++S+ G   T  ST        G   I VS   S++ ++
Sbjct: 939  ----TTGSETTTASTEGSETTTASTEGSELTTVST-------TGSETITVSAEGSETTTV 987

Query: 944  NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVS 1003
              M      +   G     VS+            ++      +   +  VS T  +  ++
Sbjct: 988  TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTIT 1047

Query: 1004 NLGQEEKKEELPKSSSAGFSFGTG---VINSTPAPANTIVTSENKSSFNLGTIETKSASV 1060
            +    E        S     + TG      ST     T V++    +    T + ++ +V
Sbjct: 1048 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTV 1107

Query: 1061 APFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS---LV 1117
            +     T+ A       T    +      AS   +    +  T  +     T+ S    V
Sbjct: 1108 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1167

Query: 1118 FGKKADNEEPKC----QPVFSFGNSEQTK-----DENSSKSTFSFSMTKPSEKESEQPAK 1168
            F   ++              S   SE T       E ++ ST     T  S   SE    
Sbjct: 1168 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTA 1227

Query: 1169 ATFAF--------GAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSN 1220
            +T           G++TST +  G+       + + ++ +ST               +S 
Sbjct: 1228 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAST---------------ASL 1272

Query: 1221 PPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGAS 1280
             P AT + G  +  VS +A G TA S+T  S  F        T +T  ++ P    P + 
Sbjct: 1273 EPTATSLTGSETTTVSITASGATAASTTVSSTTF------VLTKATDVSIQPITNTPMSG 1326

Query: 1281 SNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPG 1340
            +  T     G   T +SS   +  +  T  +A    P    N +     + GAS      
Sbjct: 1327 TRTT-----GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAH 1381

Query: 1341 FGSISSSTALFPTGS---QPAPPTFG--TVSSSSQP 1371
                ++ +   PT S   +  P + G  TVS S  P
Sbjct: 1382 GVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTP 1417



 Score = 54.7 bits (130), Expect = 7e-07
 Identities = 165/869 (18%), Positives = 302/869 (34%), Gaps = 104/869 (11%)

Query: 476  SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535
            S   T S   T + +S E TT+S     ++   T   + T  S+TGS     S+   ++T
Sbjct: 636  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 695

Query: 536  -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586
                   E  V    S   T S+  ++T ++S  GS +T     S+    +TT + T   
Sbjct: 696  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---TTSTEGSEITTASITG-S 751

Query: 587  KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646
            +T     EG         EGS      + G      ++  A  T++   + +     +  
Sbjct: 752  ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 805

Query: 647  SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706
            +S IG   +  + +S +  T   +N  ++    +  A++ +   TA    I       +T
Sbjct: 806  ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 863

Query: 707  TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766
            T + S  G         G+         ++      +  ET    T  + + T T  +E 
Sbjct: 864  TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 921

Query: 767  AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
            +ET TAS+    +TT            + +        S    +    S    +  ++V 
Sbjct: 922  SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 968

Query: 827  ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886
             + S T+ VS               EGS    +  + ++  +      E+    T     
Sbjct: 969  TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 1014

Query: 887  GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946
               +   S  +  SS+     + S++G   T+TST     G +        S++ ++   
Sbjct: 1015 TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAV--- 1067

Query: 947  SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006
                          +   SE+     +          G  +  ++   L       S  G
Sbjct: 1068 --------------YTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1113

Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066
                     ++++    + TG   +T +   +  T+ + +S    T  T  + +      
Sbjct: 1114 TTTASTAGSETTTV---YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1170

Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126
             SE        T    + G+    S  + S      TE  +    T+T+   G +     
Sbjct: 1171 VSE--------TTTVSTIGSEATTSSAAGSEATTTSTEGSE----TTTASTAGSETTTAS 1218

Query: 1127 PKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAA 1186
                   +   S     E ++  T     + PS   SE      F  G++T T A   + 
Sbjct: 1219 TAGSETTTASTS---GSETNTACTTGSETSTPSSAGSE--TNTAFIIGSET-TIASTASL 1272

Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF------ 1240
            +P  + L  + S ++T + +A G    S+T SS   V T     S  P++++        
Sbjct: 1273 EPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1330

Query: 1241 GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTSS 1298
            G    +S+S ++    D   +  S T   +     G G S+   ++TTS  G   TT S+
Sbjct: 1331 GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1390

Query: 1299 SAGSSFVF-GTGPSAPSASPAFGANQTPT 1326
               +S  F  TGP +   +     + TPT
Sbjct: 1391 REPTSSTFQETGPVSMGTN-TVSMSHTPT 1418



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 66/271 (24%), Positives = 108/271 (39%), Gaps = 30/271 (11%)

Query: 1210 GIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESST--SQSLLFSQDSKLATTSSTG 1267
            G   ++TS+++  V T     S   V+ +A  NT  +ST  S++      +   TT+ST 
Sbjct: 3    GSEATTTSTADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTA 62

Query: 1268 TAVTPFVFGPG------------------ASSNNTTTSGFGFGATTTSSSAGSSFVFGTG 1309
             + T      G                  A S NTT S  G G TTT+S AGS     T 
Sbjct: 63   GSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSG-TTTASMAGSESTISTA 121

Query: 1310 PSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSS 1369
             S  +     G   T         +  +     +  +STA    GS+    T  TV S +
Sbjct: 122  GSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTA----GSETT--TVSTVGSET 175

Query: 1370 QPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQ 1429
                     S++   S T    ++ F  GS T   +   +  + V T G+ ++T + +  
Sbjct: 176  TTAYTAD--SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGS 233

Query: 1430 PSGSGGFPFNQSPAAFTVGSNGKNVFSSSGT 1460
             + +     +++ AA T+GS    V S++G+
Sbjct: 234  ETTTASTAHSETTAASTMGSETTKV-STAGS 263



 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 57/217 (26%), Positives = 89/217 (41%), Gaps = 32/217 (14%)

Query: 1257 DSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGF---------GATTTSSSAGSSFVFG 1307
            DSK+ T SS  +  T     P A SN TT S  G            TTT+S+AGS     
Sbjct: 13   DSKVITASSMSSETT---VAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSET--- 66

Query: 1308 TGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSS 1367
            T PS   +     +        +  A   N     + S +T     GS+    T G  S 
Sbjct: 67   TTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAG--SE 124

Query: 1368 SSQPPVFGQQPSQ-SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAA 1426
            ++   + G + +  SA GS TT NS+++    S TT  +   +  + V T G+ ++T   
Sbjct: 125  TTTVSITGTETTMVSAMGSETTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYT 180

Query: 1427 SAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463
            +           +++ AA T GS    VF++   + +
Sbjct: 181  AD----------SETTAASTTGSEMTTVFTAGSETIT 207


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 207/1055 (19%), Positives = 376/1055 (35%), Gaps = 112/1055 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            TSS     + +  E TT S     ++ A T   + T+ S+TGS M    + +  +    +
Sbjct: 130  TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM----TTVFTAGSETI 185

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599
             P ++   T +V  A +   + S++  E   +S+AH  TT  ST   +T      G    
Sbjct: 186  TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 600  AE------------------ILKEGSVLDILKSPGFASPKIDSVAAQPTATS-------- 633
                                   E S      + GF +    +  ++PT  S        
Sbjct: 246  VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTM 305

Query: 634  -----PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-- 686
                 P        SS  ++    G      S+   +T  +    ++    +   ++   
Sbjct: 306  ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365

Query: 687  -----SPRDTAKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEA 739
                 S   TA   G ET   S  G    + S TG       +  +    TC   ++  A
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 740  IKCVACETPKPGT------------------CVKRALTLTVVSESAETMTA-SSSSCTVT 780
            +     ET    T                    + + T TV +  +ET TA ++ S T T
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485

Query: 781  TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS--- 836
                G        IGS        S    +   VS   SE    S   S ++TV  +   
Sbjct: 486  ASNTGLETTTVFTIGS---DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSE 542

Query: 837  LPSGGSLGLE-KFKKPEGS-------WDCELCLVQNKADSTKCLACESAKPGTKSGFKGF 888
              +  + GLE      EGS          E      +   T   +   ++  T S     
Sbjct: 543  TTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSE 602

Query: 889  DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE 948
            +T++S+++S  +S+   G  ++++  + + T+T + + G +        S++  ++    
Sbjct: 603  NTTASTADSETTSASTTGSETTTASTTSSETTTASTE-GSETTTVSTTDSETTMVSTTGS 661

Query: 949  GFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQE 1008
                +   G     VS+      V  +         ++   +  VS T    G       
Sbjct: 662  ERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTT----GSETTTTS 716

Query: 1009 EKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTS 1068
             +  E+  +S  G    T     +     +   SE  S+   G+  T +++ +  T   S
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 1069 EAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPK 1128
                E   A+  G     V  AS    +VF      E  +  + ST+            +
Sbjct: 777  IMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAGSE 831

Query: 1129 CQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTADQG 1184
              P  + G+  +  T  E S  +T S   S T  +  ES +   AT   G++T+T + +G
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTASTEG 890

Query: 1185 AAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTA 1244
            +     S    +  S +T A++ G  I   ST+ S    A+    +++   +  +   T 
Sbjct: 891  SETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTV 946

Query: 1245 ESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-- 1302
             ++ S+++  S +    TT +T  + T      G+ +   +T+G     TTT+S  GS  
Sbjct: 947  STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGSET 1003

Query: 1303 SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF 1362
            + V  TG    + S   G   T T  +    +     G    S +TA++ TGS+    T 
Sbjct: 1004 TTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE----TT 1054

Query: 1363 GTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS 1422
             T +  S+        S++   S     +++    GS TT  +   +  + V+  G+ ++
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114

Query: 1423 TPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457
            T +     + +     +++  A T GS    VF++
Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149



 Score = 95.1 bits (235), Expect = 4e-19
 Identities = 206/1019 (20%), Positives = 385/1019 (37%), Gaps = 104/1019 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T++S   F  ++   T S P+  ++  + T       P +T           V +  +  
Sbjct: 274  TTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET 333

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599
            +  S++G   +     T   +GS +T   I+ S     T+ +ST   +T     EG    
Sbjct: 334  IRASTVGSETT-----TVSTTGSETTTASIMGSE----TSTDSTTGSETTTASTEGS-ET 383

Query: 600  AEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF-----SSSGIGFGE 654
                 EGS    + + G  +  +    ++ T T        A+S+      ++S  G   
Sbjct: 384  TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443

Query: 655  SLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-----SPRDTAKQTGIETPN--KSGKTT 707
            ++ + S  +  T   +   T     A    K      S   TA  TG+ET      G  T
Sbjct: 444  TIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDT 503

Query: 708  LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767
             +AS  G         G+         ++   +     ET    T      T T  +E +
Sbjct: 504  TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLE--TTTTSTEGS 561

Query: 768  ETMTASSSSCTVTT-GTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
            E  T S++    TT  T G G       GS   +V     ++E+    +  SE   +S  
Sbjct: 562  EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA--DSENTTASTADSETTSASTT 619

Query: 827  ASSSSTVPVSLPSGGSLGLEKFKKPEGSW-DCELCLVQNKADSTKCLACESAKPGTKSGF 885
             S ++T   +     +   E  +    S  D E  +V          + E ++  T S  
Sbjct: 620  GSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSA- 678

Query: 886  KGFDTSSSSSNSAASSSFKFGVSS---SSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGS 942
             G +T+ S+  S  ++    G  +   S++G   T TST         G +I  +S +GS
Sbjct: 679  TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTE--------GSEITTASITGS 730

Query: 943  --INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQF 1000
                  +EG + +    +     S+ +   E    S   + +  ++S + +  ++     
Sbjct: 731  ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSS-ETTMASIMGSETTMA---- 785

Query: 1001 GVSNLGQEEKKEELPKSSSAGF---SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS 1057
              S +G E  K     S        +  T + ++T +   T+ T+ ++      TI   +
Sbjct: 786  --STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE------TIPAST 837

Query: 1058 ASVAPFTCKTSEAKKEEMPATKGG-FSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSL 1116
            A     T  ++E  +    +T+G   +  + E +   +A+      T    +   T+T+ 
Sbjct: 838  AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897

Query: 1117 VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQ 1176
              G +      +   + +      T  E ++ ST     T  S + SE    +T   G++
Sbjct: 898  TEGSETTTASTEGSEITTVST---TGSETTTASTEGSETTTASTEGSELTTVSTT--GSE 952

Query: 1177 TSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVS 1236
            T T + +G+     + +     S +T A++AG      ST+ S    A+ + G  +  VS
Sbjct: 953  TITVSAEGSETTTVTTMG----SETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVS 1007

Query: 1237 SSAFGNTAESST-SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATT 1295
            S+    T  S+T +++ + S +    TT +T  + T  V+  G+ +  T+T G     TT
Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG---SETT 1064

Query: 1296 TSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGS 1355
            T S+ GS             + A  A+   T   + G+        GS   +T ++ TGS
Sbjct: 1065 TVSTTGSE-----------TTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGS 1111

Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415
            +       T ++S++        S++   S T+  +++A   GS  T    T +  + V 
Sbjct: 1112 K-------TTTASTEG-------SEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVS 1157

Query: 1416 TFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSG----TSFSGRKIKTA 1470
            T G+ ++T +A+   + +     +++  A T GS      ++       S SG +  TA
Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTA 1216



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 186/973 (19%), Positives = 359/973 (36%), Gaps = 75/973 (7%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T S   T +    E +T S +   ++ A T   + T+ S+ GS     S+   ++T  ++
Sbjct: 349  TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598
                +     +    + +E++  S+T+ E   +S+     T+ ST+  +T     EG   
Sbjct: 409  TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 462

Query: 599  PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658
               +   GS      + G  +    +   + T     V+T   I S +++    G    A
Sbjct: 463  TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 515

Query: 659  GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716
             S+   +   +  + ++N  ++   ++ +   T   TG+ET   S  G    + S TG  
Sbjct: 516  VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 572

Query: 717  DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776
                   G+         ++   +     E     T      T +  +  +ET TAS++S
Sbjct: 573  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 630

Query: 777  CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836
               TT +           GS   +V   + ++E     +  SE+  +S   S ++TV  +
Sbjct: 631  SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 679

Query: 837  LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896
                   G E     EGS    + +  ++         E+    T+       + + S  
Sbjct: 680  -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 897  SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956
            + AS+      ++S+ G   T  ST     G +       SS++   + M      +  I
Sbjct: 733  TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 788

Query: 957  GDFKFGVSS-ESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELP 1015
            G     VS+  SK   V  ++         +S  +   +        S  G E       
Sbjct: 789  GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT--- 845

Query: 1016 KSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEM 1075
             +S+ G    T     +     +  +SE  ++  +G+  T +++    T  TS    E  
Sbjct: 846  -TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 1076 PATKGGFSFGNVEPASLPSASVFVLGR------TEEKQQEPVTST-SLVFGKKADNEEPK 1128
             A+  G     V      + +    G       TE  +   V++T S      A+  E  
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 1129 CQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATF--AFGAQTSTTADQGAA 1186
               V + G+   T     S++T   +    +   S + ++ T   + G++T+T +  G  
Sbjct: 965  T--VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1022

Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246
              + S    +  S +T  T+AG       T+ S     +    +++   ++ +   TA +
Sbjct: 1023 TTITS----TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078

Query: 1247 STSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSG-------FGFGATTTSSS 1299
            +  ++   S      TT+ST  + T  V+  G+ +   +T G            TTT+S+
Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAST 1138

Query: 1300 AGSSF--VFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTA--LFPTGS 1355
             GS    VF T     + S   G+  T +      A+  +  G  + ++STA     T S
Sbjct: 1139 TGSEMTTVFTTVSETTTVS-TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1197

Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415
                 T    +S S+        S+++  S     +++AF  GS TT  +  +  P+   
Sbjct: 1198 TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATS 1257

Query: 1416 TFGANSSTPAASA 1428
              G+ ++T + +A
Sbjct: 1258 LTGSETTTVSITA 1270



 Score = 85.1 bits (209), Expect = 5e-16
 Identities = 157/800 (19%), Positives = 285/800 (35%), Gaps = 65/800 (8%)

Query: 691  TAKQTGIETP-NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749
            TA   G ET  + +G  T + S TG        +G+         ++         ET  
Sbjct: 87   TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146

Query: 750  PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809
              T      T T  +  +ET  AS++   +TT      +         E +   VS    
Sbjct: 147  VSTVGSE--TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTT--VSTAGS 202

Query: 810  DNKCVSCMSEKPGSSVPASSSSTVPVSLPSG----GSLGLEKFKKPEGSWDCELCLVQNK 865
            +   VS    +  ++  A S +T   ++ S      + G E      GS   E      +
Sbjct: 203  ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---ETTAASTE 259

Query: 866  ADSTKCLACESAKPGTKSGFKGFDTSSSSSNSA----ASSSFKFGVSSSSSGPSQTLTST 921
               T     E +K  T S   GF+T+++S+  +    AS+       +S+ GP  T  ST
Sbjct: 260  DSETNTAFTEDSKTTTAST-TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVST 318

Query: 922  GN------FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975
             +      F  G +      V S++ +++        +  +G      S+          
Sbjct: 319  ASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTAST 378

Query: 976  SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035
              ++          +  VS T  +    ++   E      + S       T    +T + 
Sbjct: 379  EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438

Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095
              + +T  + S     T  T+ +     T   SE K     A   G          L + 
Sbjct: 439  EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT----AYTTGSETTTASNTGLETT 494

Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK-----DENSSKST 1150
            +VF +G          + T+ V    ++          S   SE T       E ++ ST
Sbjct: 495  TVFTIGSDTTTASTEGSETTAVSATGSE------MTTVSTEGSENTTVSTTGSETTTVST 548

Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210
                 T  S + SE    +T   GA+T+T + +G              S +T A++AG  
Sbjct: 549  TGLETTTTSTEGSEMTTVSTT--GAETTTDSTEG--------------SGTTAASTAGSE 592

Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV 1270
                ST+ S    A+    ++++  ++ +   TA +++S++   S +    TT ST  + 
Sbjct: 593  TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652

Query: 1271 TPFVFGPGA--------SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGAN 1322
            T  V   G+         S  TT S  G   T ++  +G++ V  TG      S   G+ 
Sbjct: 653  TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-GSE 711

Query: 1323 QTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380
             T T  +    +  +  G  + ++ST  +   T S     T    ++ S+        S+
Sbjct: 712  TTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771

Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440
            +   S     ++ A   GS TT  +  ++  + VFT  + ++  + +A  + +     ++
Sbjct: 772  TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 1441 SPAAFTVGSNGKNVFSSSGT 1460
            +  A T GS      S+ G+
Sbjct: 832  TIPASTAGSETTTTTSTEGS 851



 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 193/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%)

Query: 478  PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537
            P   S+  T + +  E TT       ++ A T   + T+PS TGS     S    + T  
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 68

Query: 538  NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582
            +     +   + +     TA ++GS +T+               E  + S+    TT NS
Sbjct: 69   STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS 128

Query: 583  TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642
            T   +T      G         E + +  + S    +   DS     + T   + T    
Sbjct: 129  TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 643  SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702
             S + +    G      S+   +T  +    ++    +   ++ +   T      +    
Sbjct: 181  GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 240

Query: 703  SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758
              +TT+S +G+           T D +T       +K         ET    T   +  +
Sbjct: 241  GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295

Query: 759  TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810
              T+ SE+        ET   S++S  VTT      +  +   +GS       VS    +
Sbjct: 296  ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 352

Query: 811  NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869
                S M SE    S   S ++T         +   E  +    S         +  DS 
Sbjct: 353  TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412

Query: 870  KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923
                C      T      F+T+++S+       A++S  +   +S+    + T+T+ G+ 
Sbjct: 413  TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 472

Query: 924  FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979
             K     G +   +S++G    ++  +      +   G     VS+            ++
Sbjct: 473  TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532

Query: 980  NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039
            N     +   +  VS T    G+       +  E+   S+ G    T   +ST     T 
Sbjct: 533  NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 585

Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099
             ++    +  + T ++++ + +    +T+ A       T    +      AS   +    
Sbjct: 586  ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 645

Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156
            +  T+   +  + ST+         E  +   V + G+      E S  +T S +    T
Sbjct: 646  VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 703

Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208
            K S   SE    +T           G++T+T + +G+     S    +  S +T A++ G
Sbjct: 704  KVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 759

Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265
                 +ST+SS   +A+ +   S   ++S+    T + ST+ S    +F+++S+    S+
Sbjct: 760  SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817

Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317
            T        TA +  +    A S  TTT+      TTT+S+ GS +    T  S  + + 
Sbjct: 818  TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877

Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375
              G+  T    +    +  +  G  + ++ST  +   T S     T    +  S+     
Sbjct: 878  TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937

Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435
             + S+    S T   + +    GS TT      +  +   T G+ ++T + +   + +  
Sbjct: 938  TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 997

Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460
               +++    + GS    V S++GT
Sbjct: 998  IEGSETTTVSSTGSETTTV-STTGT 1021



 Score = 74.3 bits (181), Expect = 8e-13
 Identities = 188/936 (20%), Positives = 323/936 (34%), Gaps = 102/936 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTE--- 536
            T S + T +    E TT S +   ++   T  ++ T+ S+ GS M   S+   ++T    
Sbjct: 519  TGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST 578

Query: 537  --ANVLPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDC 593
              +     S+ G  T +V  A +   + S++  E   +S+    TT  ST   +T     
Sbjct: 579  EGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAST 638

Query: 594  EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSS----G 649
            EG      +    S   ++ + G +   I S     T T     +   +S+  S      
Sbjct: 639  EGS-ETTTVSTTDSETTMVSTTG-SERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696

Query: 650  IGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTT 707
            I   E+ K  ++    T       T+   I   +   S   TA   G ET   S  G  T
Sbjct: 697  ITGSETTKVSTTGSETT----TTSTEGSEITTASITGSETTTASTEGSETTTASTEGSET 752

Query: 708  LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767
             SAS TG          +      ++ ++      +  ET K  T   +  T  V +E++
Sbjct: 753  TSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT--VFTENS 810

Query: 768  ETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPA 827
            ET  AS+++   TT +    +         E +    +  +E     +  SE   +S  +
Sbjct: 811  ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTES 870

Query: 828  SSSSTVPVSLPSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886
            S ++T         ++G E      EGS   E      +   T   + E ++  T S   
Sbjct: 871  SETTTAT-------TIGSETTTASTEGS---ETTTTSTEGSETTTASTEGSEITTVS--- 917

Query: 887  GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS---SDSGSI 943
                ++ S  + AS+      ++S+ G   T  ST        G   I VS   S++ ++
Sbjct: 918  ----TTGSETTTASTEGSETTTASTEGSELTTVST-------TGSETITVSAEGSETTTV 966

Query: 944  NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVS 1003
              M      +   G     VS+            ++      +   +  VS T  +  ++
Sbjct: 967  TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTIT 1026

Query: 1004 NLGQEEKKEELPKSSSAGFSFGTG---VINSTPAPANTIVTSENKSSFNLGTIETKSASV 1060
            +    E        S     + TG      ST     T V++    +    T + ++ +V
Sbjct: 1027 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTV 1086

Query: 1061 APFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS---LV 1117
            +     T+ A       T    +      AS   +    +  T  +     T+ S    V
Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146

Query: 1118 FGKKADNEEPKC----QPVFSFGNSEQTK-----DENSSKSTFSFSMTKPSEKESEQPAK 1168
            F   ++              S   SE T       E ++ ST     T  S   SE    
Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTA 1206

Query: 1169 ATFAF--------GAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSN 1220
            +T           G++TST +  G+       + + ++ +ST               +S 
Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAST---------------ASL 1251

Query: 1221 PPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGAS 1280
             P AT + G  +  VS +A G TA S+T  S  F        T +T  ++ P    P + 
Sbjct: 1252 EPTATSLTGSETTTVSITASGATAASTTVSSTTF------VLTKATDVSIQPITNTPMSG 1305

Query: 1281 SNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPG 1340
            +  T     G   T +SS   +  +  T  +A    P    N +     + GAS      
Sbjct: 1306 TRTT-----GTRPTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAH 1360

Query: 1341 FGSISSSTALFPTGS---QPAPPTFG--TVSSSSQP 1371
                ++ +   PT S   +  P + G  TVS S  P
Sbjct: 1361 GVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTP 1396



 Score = 54.7 bits (130), Expect = 7e-07
 Identities = 165/869 (18%), Positives = 302/869 (34%), Gaps = 104/869 (11%)

Query: 476  SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535
            S   T S   T + +S E TT+S     ++   T   + T  S+TGS     S+   ++T
Sbjct: 615  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 536  -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586
                   E  V    S   T S+  ++T ++S  GS +T     S+    +TT + T   
Sbjct: 675  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---TTSTEGSEITTASITG-S 730

Query: 587  KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646
            +T     EG         EGS      + G      ++  A  T++   + +     +  
Sbjct: 731  ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 784

Query: 647  SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706
            +S IG   +  + +S +  T   +N  ++    +  A++ +   TA    I       +T
Sbjct: 785  ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 707  TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766
            T + S  G         G+         ++      +  ET    T  + + T T  +E 
Sbjct: 843  TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 900

Query: 767  AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
            +ET TAS+    +TT            + +        S    +    S    +  ++V 
Sbjct: 901  SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 947

Query: 827  ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886
             + S T+ VS               EGS    +  + ++  +      E+    T     
Sbjct: 948  TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 887  GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946
               +   S  +  SS+     + S++G   T+TST     G +        S++ ++   
Sbjct: 994  TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAV--- 1046

Query: 947  SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006
                          +   SE+     +          G  +  ++   L       S  G
Sbjct: 1047 --------------YTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066
                     ++++    + TG   +T +   +  T+ + +S    T  T  + +      
Sbjct: 1093 TTTASTAGSETTTV---YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149

Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126
             SE        T    + G+    S  + S      TE  +    T+T+   G +     
Sbjct: 1150 VSE--------TTTVSTIGSEATTSSAAGSEATTTSTEGSE----TTTASTAGSETTTAS 1197

Query: 1127 PKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAA 1186
                   +   S     E ++  T     + PS   SE      F  G++T T A   + 
Sbjct: 1198 TAGSETTTASTS---GSETNTACTTGSETSTPSSAGSE--TNTAFIIGSET-TIASTASL 1251

Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF------ 1240
            +P  + L  + S ++T + +A G    S+T SS   V T     S  P++++        
Sbjct: 1252 EPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1309

Query: 1241 GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTSS 1298
            G    +S+S ++    D   +  S T   +     G G S+   ++TTS  G   TT S+
Sbjct: 1310 GTRPTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369

Query: 1299 SAGSSFVF-GTGPSAPSASPAFGANQTPT 1326
               +S  F  TGP +   +     + TPT
Sbjct: 1370 REPTSSTFQETGPVSMGTN-TVSMSHTPT 1397



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 50/197 (25%), Positives = 80/197 (40%), Gaps = 29/197 (14%)

Query: 1277 PGASSNNTTTSGFGF---------GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327
            P A SN TT S  G            TTT+S+AGS     T PS   +     +      
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET---TTPSPTGSQTTIVSISGSEI 65

Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ-SAFGSG 1386
              +  A   N     + S +T     GS+    T G  S ++   + G + +  SA GS 
Sbjct: 66   TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG--SETTTVSITGTETTMVSAMGSE 123

Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446
            TT NS+++    S TT  +   +  + V T G+ ++T   +           +++ AA T
Sbjct: 124  TTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYTAD----------SETTAAST 169

Query: 1447 VGSNGKNVFSSSGTSFS 1463
             GS    VF++   + +
Sbjct: 170  TGSEMTTVFTAGSETIT 186


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 207/1055 (19%), Positives = 376/1055 (35%), Gaps = 112/1055 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            TSS     + +  E TT S     ++ A T   + T+ S+TGS M    + +  +    +
Sbjct: 130  TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM----TTVFTAGSETI 185

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599
             P ++   T +V  A +   + S++  E   +S+AH  TT  ST   +T      G    
Sbjct: 186  TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 600  AE------------------ILKEGSVLDILKSPGFASPKIDSVAAQPTATS-------- 633
                                   E S      + GF +    +  ++PT  S        
Sbjct: 246  VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTM 305

Query: 634  -----PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-- 686
                 P        SS  ++    G      S+   +T  +    ++    +   ++   
Sbjct: 306  ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365

Query: 687  -----SPRDTAKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEA 739
                 S   TA   G ET   S  G    + S TG       +  +    TC   ++  A
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 740  IKCVACETPKPGT------------------CVKRALTLTVVSESAETMTA-SSSSCTVT 780
            +     ET    T                    + + T TV +  +ET TA ++ S T T
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485

Query: 781  TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS--- 836
                G        IGS        S    +   VS   SE    S   S ++TV  +   
Sbjct: 486  ASNTGLETTTVFTIGS---DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSE 542

Query: 837  LPSGGSLGLE-KFKKPEGS-------WDCELCLVQNKADSTKCLACESAKPGTKSGFKGF 888
              +  + GLE      EGS          E      +   T   +   ++  T S     
Sbjct: 543  TTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSE 602

Query: 889  DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE 948
            +T++S+++S  +S+   G  ++++  + + T+T + + G +        S++  ++    
Sbjct: 603  NTTASTADSETTSASTTGSETTTASTTSSETTTASTE-GSETTTVSTTDSETTMVSTTGS 661

Query: 949  GFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQE 1008
                +   G     VS+      V  +         ++   +  VS T    G       
Sbjct: 662  ERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTT----GSETTTTS 716

Query: 1009 EKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTS 1068
             +  E+  +S  G    T     +     +   SE  S+   G+  T +++ +  T   S
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 1069 EAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPK 1128
                E   A+  G     V  AS    +VF      E  +  + ST+            +
Sbjct: 777  IMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAGSE 831

Query: 1129 CQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTADQG 1184
              P  + G+  +  T  E S  +T S   S T  +  ES +   AT   G++T+T + +G
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTASTEG 890

Query: 1185 AAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTA 1244
            +     S    +  S +T A++ G  I   ST+ S    A+    +++   +  +   T 
Sbjct: 891  SETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTV 946

Query: 1245 ESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-- 1302
             ++ S+++  S +    TT +T  + T      G+ +   +T+G     TTT+S  GS  
Sbjct: 947  STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGSET 1003

Query: 1303 SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF 1362
            + V  TG    + S   G   T T  +    +     G    S +TA++ TGS+    T 
Sbjct: 1004 TTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE----TT 1054

Query: 1363 GTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS 1422
             T +  S+        S++   S     +++    GS TT  +   +  + V+  G+ ++
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114

Query: 1423 TPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457
            T +     + +     +++  A T GS    VF++
Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149



 Score = 95.1 bits (235), Expect = 4e-19
 Identities = 206/1019 (20%), Positives = 385/1019 (37%), Gaps = 104/1019 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T++S   F  ++   T S P+  ++  + T       P +T           V +  +  
Sbjct: 274  TTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET 333

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599
            +  S++G   +     T   +GS +T   I+ S     T+ +ST   +T     EG    
Sbjct: 334  IRASTVGSETT-----TVSTTGSETTTASIMGSE----TSTDSTTGSETTTASTEGS-ET 383

Query: 600  AEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF-----SSSGIGFGE 654
                 EGS    + + G  +  +    ++ T T        A+S+      ++S  G   
Sbjct: 384  TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443

Query: 655  SLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-----SPRDTAKQTGIETPN--KSGKTT 707
            ++ + S  +  T   +   T     A    K      S   TA  TG+ET      G  T
Sbjct: 444  TIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDT 503

Query: 708  LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767
             +AS  G         G+         ++   +     ET    T      T T  +E +
Sbjct: 504  TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLE--TTTTSTEGS 561

Query: 768  ETMTASSSSCTVTT-GTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
            E  T S++    TT  T G G       GS   +V     ++E+    +  SE   +S  
Sbjct: 562  EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA--DSENTTASTADSETTSASTT 619

Query: 827  ASSSSTVPVSLPSGGSLGLEKFKKPEGSW-DCELCLVQNKADSTKCLACESAKPGTKSGF 885
             S ++T   +     +   E  +    S  D E  +V          + E ++  T S  
Sbjct: 620  GSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSA- 678

Query: 886  KGFDTSSSSSNSAASSSFKFGVSS---SSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGS 942
             G +T+ S+  S  ++    G  +   S++G   T TST         G +I  +S +GS
Sbjct: 679  TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTE--------GSEITTASITGS 730

Query: 943  --INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQF 1000
                  +EG + +    +     S+ +   E    S   + +  ++S + +  ++     
Sbjct: 731  ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSS-ETTMASIMGSETTMA---- 785

Query: 1001 GVSNLGQEEKKEELPKSSSAGF---SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS 1057
              S +G E  K     S        +  T + ++T +   T+ T+ ++      TI   +
Sbjct: 786  --STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE------TIPAST 837

Query: 1058 ASVAPFTCKTSEAKKEEMPATKGG-FSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSL 1116
            A     T  ++E  +    +T+G   +  + E +   +A+      T    +   T+T+ 
Sbjct: 838  AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897

Query: 1117 VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQ 1176
              G +      +   + +      T  E ++ ST     T  S + SE    +T   G++
Sbjct: 898  TEGSETTTASTEGSEITTVST---TGSETTTASTEGSETTTASTEGSELTTVSTT--GSE 952

Query: 1177 TSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVS 1236
            T T + +G+     + +     S +T A++AG      ST+ S    A+ + G  +  VS
Sbjct: 953  TITVSAEGSETTTVTTMG----SETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVS 1007

Query: 1237 SSAFGNTAESST-SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATT 1295
            S+    T  S+T +++ + S +    TT +T  + T  V+  G+ +  T+T G     TT
Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG---SETT 1064

Query: 1296 TSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGS 1355
            T S+ GS             + A  A+   T   + G+        GS   +T ++ TGS
Sbjct: 1065 TVSTTGSE-----------TTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGS 1111

Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415
            +       T ++S++        S++   S T+  +++A   GS  T    T +  + V 
Sbjct: 1112 K-------TTTASTEG-------SEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVS 1157

Query: 1416 TFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSG----TSFSGRKIKTA 1470
            T G+ ++T +A+   + +     +++  A T GS      ++       S SG +  TA
Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTA 1216



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 186/973 (19%), Positives = 359/973 (36%), Gaps = 75/973 (7%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T S   T +    E +T S +   ++ A T   + T+ S+ GS     S+   ++T  ++
Sbjct: 349  TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598
                +     +    + +E++  S+T+ E   +S+     T+ ST+  +T     EG   
Sbjct: 409  TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 462

Query: 599  PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658
               +   GS      + G  +    +   + T     V+T   I S +++    G    A
Sbjct: 463  TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 515

Query: 659  GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716
             S+   +   +  + ++N  ++   ++ +   T   TG+ET   S  G    + S TG  
Sbjct: 516  VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 572

Query: 717  DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776
                   G+         ++   +     E     T      T +  +  +ET TAS++S
Sbjct: 573  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 630

Query: 777  CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836
               TT +           GS   +V   + ++E     +  SE+  +S   S ++TV  +
Sbjct: 631  SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 679

Query: 837  LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896
                   G E     EGS    + +  ++         E+    T+       + + S  
Sbjct: 680  -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 897  SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956
            + AS+      ++S+ G   T  ST     G +       SS++   + M      +  I
Sbjct: 733  TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 788

Query: 957  GDFKFGVSS-ESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELP 1015
            G     VS+  SK   V  ++         +S  +   +        S  G E       
Sbjct: 789  GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT--- 845

Query: 1016 KSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEM 1075
             +S+ G    T     +     +  +SE  ++  +G+  T +++    T  TS    E  
Sbjct: 846  -TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 1076 PATKGGFSFGNVEPASLPSASVFVLGR------TEEKQQEPVTST-SLVFGKKADNEEPK 1128
             A+  G     V      + +    G       TE  +   V++T S      A+  E  
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 1129 CQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATF--AFGAQTSTTADQGAA 1186
               V + G+   T     S++T   +    +   S + ++ T   + G++T+T +  G  
Sbjct: 965  T--VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1022

Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246
              + S    +  S +T  T+AG       T+ S     +    +++   ++ +   TA +
Sbjct: 1023 TTITS----TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078

Query: 1247 STSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSG-------FGFGATTTSSS 1299
            +  ++   S      TT+ST  + T  V+  G+ +   +T G            TTT+S+
Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAST 1138

Query: 1300 AGSSF--VFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTA--LFPTGS 1355
             GS    VF T     + S   G+  T +      A+  +  G  + ++STA     T S
Sbjct: 1139 TGSEMTTVFTTVSETTTVS-TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1197

Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415
                 T    +S S+        S+++  S     +++AF  GS TT  +  +  P+   
Sbjct: 1198 TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATS 1257

Query: 1416 TFGANSSTPAASA 1428
              G+ ++T + +A
Sbjct: 1258 LTGSETTTVSITA 1270



 Score = 85.1 bits (209), Expect = 5e-16
 Identities = 157/800 (19%), Positives = 285/800 (35%), Gaps = 65/800 (8%)

Query: 691  TAKQTGIETP-NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749
            TA   G ET  + +G  T + S TG        +G+         ++         ET  
Sbjct: 87   TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146

Query: 750  PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809
              T      T T  +  +ET  AS++   +TT      +         E +   VS    
Sbjct: 147  VSTVGSE--TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTT--VSTAGS 202

Query: 810  DNKCVSCMSEKPGSSVPASSSSTVPVSLPSG----GSLGLEKFKKPEGSWDCELCLVQNK 865
            +   VS    +  ++  A S +T   ++ S      + G E      GS   E      +
Sbjct: 203  ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---ETTAASTE 259

Query: 866  ADSTKCLACESAKPGTKSGFKGFDTSSSSSNSA----ASSSFKFGVSSSSSGPSQTLTST 921
               T     E +K  T S   GF+T+++S+  +    AS+       +S+ GP  T  ST
Sbjct: 260  DSETNTAFTEDSKTTTAST-TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVST 318

Query: 922  GN------FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975
             +      F  G +      V S++ +++        +  +G      S+          
Sbjct: 319  ASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTAST 378

Query: 976  SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035
              ++          +  VS T  +    ++   E      + S       T    +T + 
Sbjct: 379  EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438

Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095
              + +T  + S     T  T+ +     T   SE K     A   G          L + 
Sbjct: 439  EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT----AYTTGSETTTASNTGLETT 494

Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK-----DENSSKST 1150
            +VF +G          + T+ V    ++          S   SE T       E ++ ST
Sbjct: 495  TVFTIGSDTTTASTEGSETTAVSATGSE------MTTVSTEGSENTTVSTTGSETTTVST 548

Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210
                 T  S + SE    +T   GA+T+T + +G              S +T A++AG  
Sbjct: 549  TGLETTTTSTEGSEMTTVSTT--GAETTTDSTEG--------------SGTTAASTAGSE 592

Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV 1270
                ST+ S    A+    ++++  ++ +   TA +++S++   S +    TT ST  + 
Sbjct: 593  TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652

Query: 1271 TPFVFGPGA--------SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGAN 1322
            T  V   G+         S  TT S  G   T ++  +G++ V  TG      S   G+ 
Sbjct: 653  TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-GSE 711

Query: 1323 QTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380
             T T  +    +  +  G  + ++ST  +   T S     T    ++ S+        S+
Sbjct: 712  TTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771

Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440
            +   S     ++ A   GS TT  +  ++  + VFT  + ++  + +A  + +     ++
Sbjct: 772  TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 1441 SPAAFTVGSNGKNVFSSSGT 1460
            +  A T GS      S+ G+
Sbjct: 832  TIPASTAGSETTTTTSTEGS 851



 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 193/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%)

Query: 478  PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537
            P   S+  T + +  E TT       ++ A T   + T+PS TGS     S    + T  
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 68

Query: 538  NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582
            +     +   + +     TA ++GS +T+               E  + S+    TT NS
Sbjct: 69   STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS 128

Query: 583  TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642
            T   +T      G         E + +  + S    +   DS     + T   + T    
Sbjct: 129  TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 643  SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702
             S + +    G      S+   +T  +    ++    +   ++ +   T      +    
Sbjct: 181  GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 240

Query: 703  SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758
              +TT+S +G+           T D +T       +K         ET    T   +  +
Sbjct: 241  GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295

Query: 759  TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810
              T+ SE+        ET   S++S  VTT      +  +   +GS       VS    +
Sbjct: 296  ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 352

Query: 811  NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869
                S M SE    S   S ++T         +   E  +    S         +  DS 
Sbjct: 353  TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412

Query: 870  KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923
                C      T      F+T+++S+       A++S  +   +S+    + T+T+ G+ 
Sbjct: 413  TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 472

Query: 924  FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979
             K     G +   +S++G    ++  +      +   G     VS+            ++
Sbjct: 473  TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532

Query: 980  NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039
            N     +   +  VS T    G+       +  E+   S+ G    T   +ST     T 
Sbjct: 533  NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 585

Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099
             ++    +  + T ++++ + +    +T+ A       T    +      AS   +    
Sbjct: 586  ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 645

Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156
            +  T+   +  + ST+         E  +   V + G+      E S  +T S +    T
Sbjct: 646  VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 703

Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208
            K S   SE    +T           G++T+T + +G+     S    +  S +T A++ G
Sbjct: 704  KVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 759

Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265
                 +ST+SS   +A+ +   S   ++S+    T + ST+ S    +F+++S+    S+
Sbjct: 760  SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817

Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317
            T        TA +  +    A S  TTT+      TTT+S+ GS +    T  S  + + 
Sbjct: 818  TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877

Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375
              G+  T    +    +  +  G  + ++ST  +   T S     T    +  S+     
Sbjct: 878  TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937

Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435
             + S+    S T   + +    GS TT      +  +   T G+ ++T + +   + +  
Sbjct: 938  TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 997

Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460
               +++    + GS    V S++GT
Sbjct: 998  IEGSETTTVSSTGSETTTV-STTGT 1021



 Score = 74.3 bits (181), Expect = 8e-13
 Identities = 188/936 (20%), Positives = 323/936 (34%), Gaps = 102/936 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTE--- 536
            T S + T +    E TT S +   ++   T  ++ T+ S+ GS M   S+   ++T    
Sbjct: 519  TGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST 578

Query: 537  --ANVLPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDC 593
              +     S+ G  T +V  A +   + S++  E   +S+    TT  ST   +T     
Sbjct: 579  EGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAST 638

Query: 594  EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSS----G 649
            EG      +    S   ++ + G +   I S     T T     +   +S+  S      
Sbjct: 639  EGS-ETTTVSTTDSETTMVSTTG-SERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696

Query: 650  IGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTT 707
            I   E+ K  ++    T       T+   I   +   S   TA   G ET   S  G  T
Sbjct: 697  ITGSETTKVSTTGSETT----TTSTEGSEITTASITGSETTTASTEGSETTTASTEGSET 752

Query: 708  LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767
             SAS TG          +      ++ ++      +  ET K  T   +  T  V +E++
Sbjct: 753  TSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT--VFTENS 810

Query: 768  ETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPA 827
            ET  AS+++   TT +    +         E +    +  +E     +  SE   +S  +
Sbjct: 811  ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTES 870

Query: 828  SSSSTVPVSLPSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886
            S ++T         ++G E      EGS   E      +   T   + E ++  T S   
Sbjct: 871  SETTTAT-------TIGSETTTASTEGS---ETTTTSTEGSETTTASTEGSEITTVS--- 917

Query: 887  GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS---SDSGSI 943
                ++ S  + AS+      ++S+ G   T  ST        G   I VS   S++ ++
Sbjct: 918  ----TTGSETTTASTEGSETTTASTEGSELTTVST-------TGSETITVSAEGSETTTV 966

Query: 944  NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVS 1003
              M      +   G     VS+            ++      +   +  VS T  +  ++
Sbjct: 967  TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTIT 1026

Query: 1004 NLGQEEKKEELPKSSSAGFSFGTG---VINSTPAPANTIVTSENKSSFNLGTIETKSASV 1060
            +    E        S     + TG      ST     T V++    +    T + ++ +V
Sbjct: 1027 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTV 1086

Query: 1061 APFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS---LV 1117
            +     T+ A       T    +      AS   +    +  T  +     T+ S    V
Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146

Query: 1118 FGKKADNEEPKC----QPVFSFGNSEQTK-----DENSSKSTFSFSMTKPSEKESEQPAK 1168
            F   ++              S   SE T       E ++ ST     T  S   SE    
Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTA 1206

Query: 1169 ATFAF--------GAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSN 1220
            +T           G++TST +  G+       + + ++ +ST               +S 
Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAST---------------ASL 1251

Query: 1221 PPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGAS 1280
             P AT + G  +  VS +A G TA S+T  S  F        T +T  ++ P    P + 
Sbjct: 1252 EPTATSLTGSETTTVSITASGATAASTTVSSTTF------VLTKATDVSIQPITNTPMSG 1305

Query: 1281 SNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPG 1340
            +  T     G   T +SS   +  +  T  +A    P    N +     + GAS      
Sbjct: 1306 TRTT-----GTRPTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAH 1360

Query: 1341 FGSISSSTALFPTGS---QPAPPTFG--TVSSSSQP 1371
                ++ +   PT S   +  P + G  TVS S  P
Sbjct: 1361 GVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTP 1396



 Score = 54.7 bits (130), Expect = 7e-07
 Identities = 165/869 (18%), Positives = 302/869 (34%), Gaps = 104/869 (11%)

Query: 476  SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535
            S   T S   T + +S E TT+S     ++   T   + T  S+TGS     S+   ++T
Sbjct: 615  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 536  -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586
                   E  V    S   T S+  ++T ++S  GS +T     S+    +TT + T   
Sbjct: 675  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---TTSTEGSEITTASITG-S 730

Query: 587  KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646
            +T     EG         EGS      + G      ++  A  T++   + +     +  
Sbjct: 731  ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 784

Query: 647  SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706
            +S IG   +  + +S +  T   +N  ++    +  A++ +   TA    I       +T
Sbjct: 785  ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 707  TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766
            T + S  G         G+         ++      +  ET    T  + + T T  +E 
Sbjct: 843  TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 900

Query: 767  AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
            +ET TAS+    +TT            + +        S    +    S    +  ++V 
Sbjct: 901  SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 947

Query: 827  ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886
             + S T+ VS               EGS    +  + ++  +      E+    T     
Sbjct: 948  TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 887  GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946
               +   S  +  SS+     + S++G   T+TST     G +        S++ ++   
Sbjct: 994  TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAV--- 1046

Query: 947  SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006
                          +   SE+     +          G  +  ++   L       S  G
Sbjct: 1047 --------------YTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066
                     ++++    + TG   +T +   +  T+ + +S    T  T  + +      
Sbjct: 1093 TTTASTAGSETTTV---YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149

Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126
             SE        T    + G+    S  + S      TE  +    T+T+   G +     
Sbjct: 1150 VSE--------TTTVSTIGSEATTSSAAGSEATTTSTEGSE----TTTASTAGSETTTAS 1197

Query: 1127 PKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAA 1186
                   +   S     E ++  T     + PS   SE      F  G++T T A   + 
Sbjct: 1198 TAGSETTTASTS---GSETNTACTTGSETSTPSSAGSE--TNTAFIIGSET-TIASTASL 1251

Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF------ 1240
            +P  + L  + S ++T + +A G    S+T SS   V T     S  P++++        
Sbjct: 1252 EPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1309

Query: 1241 GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTSS 1298
            G    +S+S ++    D   +  S T   +     G G S+   ++TTS  G   TT S+
Sbjct: 1310 GTRPTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369

Query: 1299 SAGSSFVF-GTGPSAPSASPAFGANQTPT 1326
               +S  F  TGP +   +     + TPT
Sbjct: 1370 REPTSSTFQETGPVSMGTN-TVSMSHTPT 1397



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 50/197 (25%), Positives = 80/197 (40%), Gaps = 29/197 (14%)

Query: 1277 PGASSNNTTTSGFGF---------GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327
            P A SN TT S  G            TTT+S+AGS     T PS   +     +      
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET---TTPSPTGSQTTIVSISGSEI 65

Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ-SAFGSG 1386
              +  A   N     + S +T     GS+    T G  S ++   + G + +  SA GS 
Sbjct: 66   TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG--SETTTVSITGTETTMVSAMGSE 123

Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446
            TT NS+++    S TT  +   +  + V T G+ ++T   +           +++ AA T
Sbjct: 124  TTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYTAD----------SETTAAST 169

Query: 1447 VGSNGKNVFSSSGTSFS 1463
             GS    VF++   + +
Sbjct: 170  TGSEMTTVFTAGSETIT 186


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 216/1057 (20%), Positives = 377/1057 (35%), Gaps = 116/1057 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            TSS     + +  E TT S     ++ A T   + T+ S+TGS M       V +  +  
Sbjct: 130  TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM-----TTVFTAGSET 184

Query: 540  LPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598
            + PS+ G  T +V  A +   + S++  E   +S+AH  TT  ST   +T      G   
Sbjct: 185  ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244

Query: 599  PAEI------------------LKEGSVLDILKSPGFASPKIDSVAAQPTATS------- 633
                                    E S      + GF +    +  ++PT  S       
Sbjct: 245  TVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETT 304

Query: 634  ------PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLS 687
                  P        SS  ++    G      S+   +T  +    ++    +   ++ S
Sbjct: 305  MASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETS 364

Query: 688  PRDT-------AKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPE 738
               T       A   G ET   S  G    + S TG       +  +    TC   ++  
Sbjct: 365  TDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMT 424

Query: 739  AIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWE 798
            A+     ET    T     +T+   S+S  T  ++  S T T  T G   K     GS  
Sbjct: 425  AVSTTVFETTTAST-EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSET 483

Query: 799  CSVC-----------------CVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS---L 837
             +                     S    +   VS   SE    S   S ++TV  +    
Sbjct: 484  TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 838  PSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSS---- 892
             +  + GLE      EGS   E+  V      T   + E +   T +   G +T++    
Sbjct: 544  TTVSTTGLETTTTSTEGS---EMTTVSTTGAETTTDSTEGSGT-TAASTAGSETTTVSTA 599

Query: 893  SSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKF---GDQGGFKIGVS---SDSGSINPM 946
             S N+ AS++     S+S++G   T  ST + +      +G     VS   S++  ++  
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 947  SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006
                  +   G     VS+      V  +         ++   +  VS T    G     
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTT----GSETTT 714

Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066
               +  E+  +S  G    T     +     +   SE  S+   G+  T +++ +  T  
Sbjct: 715  TSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTM 774

Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126
             S    E   A+  G     V  AS    +VF      E  +  + ST+           
Sbjct: 775  ASIMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAG 829

Query: 1127 PKCQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTAD 1182
             +  P  + G+  +  T  E S  +T S   S T  +  ES +   AT   G++T+T + 
Sbjct: 830  SETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTAST 888

Query: 1183 QGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGN 1242
            +G+     S    +  S +T A++ G  I   ST+ S    A+    +++   +  +   
Sbjct: 889  EGSETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELT 944

Query: 1243 TAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS 1302
            T  ++ S+++  S +    TT +T  + T      G+ +   +T+G     TTT+S  GS
Sbjct: 945  TVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGS 1001

Query: 1303 --SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPP 1360
              + V  TG    + S   G   T T  +    +     G    S +TA++ TGS+    
Sbjct: 1002 ETTTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE---- 1052

Query: 1361 TFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGAN 1420
            T  T +  S+        S++   S     +++    GS TT  +   +  + V+  G+ 
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 1421 SSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457
            ++T +     + +     +++  A T GS    VF++
Sbjct: 1113 TTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149



 Score = 94.4 bits (233), Expect = 7e-19
 Identities = 201/994 (20%), Positives = 377/994 (37%), Gaps = 100/994 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T++S   F  ++   T S P+  ++  + T       P +T           V +  +  
Sbjct: 274  TTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET 333

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599
            +  S++G   +     T   +GS +T   I+ S     T+ +ST   +T     EG    
Sbjct: 334  IRASTVGSETT-----TVSTTGSETTTASIMGSE----TSTDSTTGSETTTASTEGS-ET 383

Query: 600  AEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF-----SSSGIGFGE 654
                 EGS    + + G  +  +    ++ T T        A+S+      ++S  G   
Sbjct: 384  TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443

Query: 655  SLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-----SPRDTAKQTGIETPN--KSGKTT 707
            ++ + S  +  T   +   T     A    K      S   TA  TG+ET      G  T
Sbjct: 444  TIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDT 503

Query: 708  LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767
             +AS  G         G+         ++   +     ET    T      T T  +E +
Sbjct: 504  TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLE--TTTTSTEGS 561

Query: 768  ETMTASSSSCTVTT-GTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
            E  T S++    TT  T G G       GS   +V     ++E+    +  SE   +S  
Sbjct: 562  EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA--DSENTTASTADSETTSASTT 619

Query: 827  ASSSSTVPVSLPSGGSLGLEKFKKPEGSW-DCELCLVQNKADSTKCLACESAKPGTKSGF 885
             S ++T   +     +   E  +    S  D E  +V          + E ++  T S  
Sbjct: 620  GSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSA- 678

Query: 886  KGFDTSSSSSNSAASSSFKFGVSS---SSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGS 942
             G +T+ S+  S  ++    G  +   S++G   T TST         G +I  +S +GS
Sbjct: 679  TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTE--------GSEITTASITGS 730

Query: 943  --INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQF 1000
                  +EG + +    +     S+ +   E    S   + +  ++S + +  ++     
Sbjct: 731  ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSS-ETTMASIMGSETTMA---- 785

Query: 1001 GVSNLGQEEKKEELPKSSSAGF---SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS 1057
              S +G E  K     S        +  T + ++T +   T+ T+ ++      TI   +
Sbjct: 786  --STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE------TIPAST 837

Query: 1058 ASVAPFTCKTSEAKKEEMPATKGG-FSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSL 1116
            A     T  ++E  +    +T+G   +  + E +   +A+      T    +   T+T+ 
Sbjct: 838  AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897

Query: 1117 VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQ 1176
              G +      +   + +      T  E ++ ST     T  S + SE    +T   G++
Sbjct: 898  TEGSETTTASTEGSEITTVST---TGSETTTASTEGSETTTASTEGSELTTVSTT--GSE 952

Query: 1177 TSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVS 1236
            T T + +G+     + +     S +T A++AG      ST+ S    A+ + G  +  VS
Sbjct: 953  TITVSAEGSETTTVTTMG----SETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVS 1007

Query: 1237 SSAFGNTAESST-SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATT 1295
            S+    T  S+T +++ + S +    TT +T  + T  V+  G+ +  T+T G     TT
Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG---SETT 1064

Query: 1296 TSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGS 1355
            T S+ GS             + A  A+   T   + G+        GS   +T ++ TGS
Sbjct: 1065 TVSTTGSE-----------TTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGS 1111

Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415
            +       T ++S++        S++   S T+  +++A   GS  T    T +  + V 
Sbjct: 1112 K-------TTTASTEG-------SEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVS 1157

Query: 1416 TFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGS 1449
            T G+ ++T +A+   + +     +++  A T GS
Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAGS 1191



 Score = 88.6 bits (218), Expect = 4e-17
 Identities = 188/993 (18%), Positives = 361/993 (36%), Gaps = 105/993 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T S   T +    E +T S +   ++ A T   + T+ S+ GS     S+   ++T  ++
Sbjct: 349  TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598
                +     +    + +E++  S+T+ E   +S+     T+ ST+  +T     EG   
Sbjct: 409  TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 462

Query: 599  PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658
               +   GS      + G  +    +   + T     V+T   I S +++    G    A
Sbjct: 463  TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 515

Query: 659  GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716
             S+   +   +  + ++N  ++   ++ +   T   TG+ET   S  G    + S TG  
Sbjct: 516  VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 572

Query: 717  DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776
                   G+         ++   +     E     T      T +  +  +ET TAS++S
Sbjct: 573  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 630

Query: 777  CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836
               TT +           GS   +V   + ++E     +  SE+  +S   S ++TV  +
Sbjct: 631  SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 679

Query: 837  LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896
                   G E     EGS    + +  ++         E+    T+       + + S  
Sbjct: 680  -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 897  SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956
            + AS+      ++S+ G   T  ST     G +       SS++   + M      +  I
Sbjct: 733  TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 788

Query: 957  GDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPK 1016
            G     VS+ S           +N +  ++S  ++  +       VS  G E     +P 
Sbjct: 789  GSETTKVSTASSKMTTVF---TENSETTIASTTASETTT------VSTAGSET----IPA 835

Query: 1017 SSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMP 1076
            S++      T    ST     T  ++E   +    T  +++ +      +T+ A  E   
Sbjct: 836  STAGS---ETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSE 892

Query: 1077 ATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKK---ADNEEPKCQPVF 1133
             T           AS   + +  +  T  +     T+T+   G +   A  E  +   V 
Sbjct: 893  TTTTSTEGSETTTASTEGSEITTVSTTGSE-----TTTASTEGSETTTASTEGSELTTVS 947

Query: 1134 SFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAF--GAQTSTTADQGAAKPVFS 1191
            + G+   T     S++T   +M   +   S   ++ T     G++T+T + +G+     S
Sbjct: 948  TTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVS 1007

Query: 1192 FLNN-----SSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246
               +     S++ + T  TS  G    + T++ +   A +  G  +   S+     T  S
Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVS 1067

Query: 1247 STSQSLLFSQDSKL-----------ATTSSTGTAVTPFVFGPGA---------------- 1279
            +T      +  + L            TT+ST  + T  V+  G+                
Sbjct: 1068 TTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1280 --SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPN 1337
              SS  TT S  G   TT  ++   +    T  S  + S A G+  T T  +    +  +
Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS 1187

Query: 1338 PPGFGSISSSTA--LFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAF 1395
              G  + ++STA     T S     T    +S S+        S+++  S     +++AF
Sbjct: 1188 TAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAF 1247

Query: 1396 QFGSSTTNFNFTNNSPSGVFTFGANSSTPAASA 1428
              GS TT  +  +  P+     G+ ++T + +A
Sbjct: 1248 IIGSETTIASTASLEPTATSLTGSETTTVSITA 1280



 Score = 85.1 bits (209), Expect = 5e-16
 Identities = 157/800 (19%), Positives = 285/800 (35%), Gaps = 65/800 (8%)

Query: 691  TAKQTGIETP-NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749
            TA   G ET  + +G  T + S TG        +G+         ++         ET  
Sbjct: 87   TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146

Query: 750  PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809
              T      T T  +  +ET  AS++   +TT      +         E +   VS    
Sbjct: 147  VSTVGSE--TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTT--VSTAGS 202

Query: 810  DNKCVSCMSEKPGSSVPASSSSTVPVSLPSG----GSLGLEKFKKPEGSWDCELCLVQNK 865
            +   VS    +  ++  A S +T   ++ S      + G E      GS   E      +
Sbjct: 203  ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---ETTAASTE 259

Query: 866  ADSTKCLACESAKPGTKSGFKGFDTSSSSSNSA----ASSSFKFGVSSSSSGPSQTLTST 921
               T     E +K  T S   GF+T+++S+  +    AS+       +S+ GP  T  ST
Sbjct: 260  DSETNTAFTEDSKTTTAST-TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVST 318

Query: 922  GN------FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975
             +      F  G +      V S++ +++        +  +G      S+          
Sbjct: 319  ASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTAST 378

Query: 976  SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035
              ++          +  VS T  +    ++   E      + S       T    +T + 
Sbjct: 379  EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438

Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095
              + +T  + S     T  T+ +     T   SE K     A   G          L + 
Sbjct: 439  EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT----AYTTGSETTTASNTGLETT 494

Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK-----DENSSKST 1150
            +VF +G          + T+ V    ++          S   SE T       E ++ ST
Sbjct: 495  TVFTIGSDTTTASTEGSETTAVSATGSE------MTTVSTEGSENTTVSTTGSETTTVST 548

Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210
                 T  S + SE    +T   GA+T+T + +G              S +T A++AG  
Sbjct: 549  TGLETTTTSTEGSEMTTVSTT--GAETTTDSTEG--------------SGTTAASTAGSE 592

Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV 1270
                ST+ S    A+    ++++  ++ +   TA +++S++   S +    TT ST  + 
Sbjct: 593  TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652

Query: 1271 TPFVFGPGA--------SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGAN 1322
            T  V   G+         S  TT S  G   T ++  +G++ V  TG      S   G+ 
Sbjct: 653  TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-GSE 711

Query: 1323 QTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380
             T T  +    +  +  G  + ++ST  +   T S     T    ++ S+        S+
Sbjct: 712  TTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771

Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440
            +   S     ++ A   GS TT  +  ++  + VFT  + ++  + +A  + +     ++
Sbjct: 772  TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 1441 SPAAFTVGSNGKNVFSSSGT 1460
            +  A T GS      S+ G+
Sbjct: 832  TIPASTAGSETTTTTSTEGS 851



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 219/1063 (20%), Positives = 383/1063 (36%), Gaps = 157/1063 (14%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T S   T + +  E TT+       +   T   + T+ S+ GS +   S+   ++T A+ 
Sbjct: 399  TGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTAST 458

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSST------LEPIISSSAHHVTTVNSTNCKKTPPEDC 593
                +   T +    KTA  +GS +T      LE     +    TT  ST   +T     
Sbjct: 459  EGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSA 518

Query: 594  EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSP-------VVYTRPAISSFS 646
             G      +  EGS    + + G  +  + +   + T TS        V  T    ++ S
Sbjct: 519  TGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDS 577

Query: 647  SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706
            + G G   +  AGS    +T  +    ++N   +   ++ +   +A  TG ET   S  +
Sbjct: 578  TEGSGTTAASTAGS----ETTTVSTADSENTTASTADSETT---SASTTGSETTTASTTS 630

Query: 707  TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766
            + + + +  G +    + T D +T +V                  T  +R +T T   E 
Sbjct: 631  SETTTASTEGSE-TTTVSTTDSETTMVST----------------TGSERTITST---EG 670

Query: 767  AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSN-----NAEDNKCVSCM---S 818
            +ET T S++    T  T G G       GS    V    +     + E ++  +     S
Sbjct: 671  SETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGS 730

Query: 819  EKPGSSVPASSSSTVPVS---LPSGGSLGLEKFKKPEGSWDCELCLVQ-NKADSTKCLAC 874
            E   +S   S ++T         S  + G E       S +  +  +  ++      +  
Sbjct: 731  ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGS 790

Query: 875  ESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSG----PSQTLTSTGNFKFGDQG 930
            E+ K  T S       + +S  + AS++     + S++G    P+ T  S        +G
Sbjct: 791  ETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEG 850

Query: 931  GFKIGVS---SDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSS 987
                  S   S++ + +  S     +  IG      S+E           ++        
Sbjct: 851  SETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG 910

Query: 988  GLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVT--SENK 1045
                 VS T    G        +  E   +S+ G    T  +++T +   T+    SE  
Sbjct: 911  SEITTVSTT----GSETTTASTEGSETTTASTEGSELTT--VSTTGSETITVSAEGSETT 964

Query: 1046 SSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGR--- 1102
            +   +G+  T +++    T   S A  E   A+  G     V      + +V   G    
Sbjct: 965  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024

Query: 1103 ---TEEKQQEPVTS----TSLVFGKKADN-----EEPKCQPVFSFGNSEQTKD----ENS 1146
               TE  +   VT+    T+ V+   ++      E  +   V + G+   T      E +
Sbjct: 1025 ITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084

Query: 1147 SKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPAT- 1205
            + ST     T  S   SE      +  G++T+T + +G+     S  ++ ++++ST  + 
Sbjct: 1085 TVSTSGSGTTTASTAGSE--TTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSE 1142

Query: 1206 ----------SAGGGIFGS--STSSSNPPVATFVFGQSSNPVSSSAFGN-TAESSTSQSL 1252
                      +      GS  +TSS+    AT    + S   ++S  G+ T  +ST+ S 
Sbjct: 1143 MTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS- 1201

Query: 1253 LFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS----SFVFG- 1307
                     TT+ST  + T      G+ +N   T+G     T+T SSAGS    +F+ G 
Sbjct: 1202 -------ETTTASTAGSETTTASTSGSETNTACTTG---SETSTPSSAGSETNTAFIIGS 1251

Query: 1308 ------TGPSAPSASPAFGANQTPTFGQSQGAS---------------------QP--NP 1338
                  T    P+A+   G+  T     + GA+                     QP  N 
Sbjct: 1252 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1311

Query: 1339 PGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFG 1398
            P  G+ ++ T L  + S    P     +S++   V G   + S  G+ T   SS+    G
Sbjct: 1312 PMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHG 1371

Query: 1399 SSTTNFNFTNNSPS-----GVFTFGAN----SSTPAASAQPSG 1432
              TT  +    + S     G  + G N    S TP    +PSG
Sbjct: 1372 VRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPSG 1414



 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 193/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%)

Query: 478  PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537
            P   S+  T + +  E TT       ++ A T   + T+PS TGS     S    + T  
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 68

Query: 538  NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582
            +     +   + +     TA ++GS +T+               E  + S+    TT NS
Sbjct: 69   STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS 128

Query: 583  TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642
            T   +T      G         E + +  + S    +   DS     + T   + T    
Sbjct: 129  TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 643  SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702
             S + +    G      S+   +T  +    ++    +   ++ +   T      +    
Sbjct: 181  GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 240

Query: 703  SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758
              +TT+S +G+           T D +T       +K         ET    T   +  +
Sbjct: 241  GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295

Query: 759  TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810
              T+ SE+        ET   S++S  VTT      +  +   +GS       VS    +
Sbjct: 296  ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 352

Query: 811  NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869
                S M SE    S   S ++T         +   E  +    S         +  DS 
Sbjct: 353  TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412

Query: 870  KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923
                C      T      F+T+++S+       A++S  +   +S+    + T+T+ G+ 
Sbjct: 413  TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 472

Query: 924  FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979
             K     G +   +S++G    ++  +      +   G     VS+            ++
Sbjct: 473  TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532

Query: 980  NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039
            N     +   +  VS T    G+       +  E+   S+ G    T   +ST     T 
Sbjct: 533  NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 585

Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099
             ++    +  + T ++++ + +    +T+ A       T    +      AS   +    
Sbjct: 586  ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 645

Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156
            +  T+   +  + ST+         E  +   V + G+      E S  +T S +    T
Sbjct: 646  VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 703

Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208
            K S   SE    +T           G++T+T + +G+     S    +  S +T A++ G
Sbjct: 704  KVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 759

Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265
                 +ST+SS   +A+ +   S   ++S+    T + ST+ S    +F+++S+    S+
Sbjct: 760  SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817

Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317
            T        TA +  +    A S  TTT+      TTT+S+ GS +    T  S  + + 
Sbjct: 818  TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877

Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375
              G+  T    +    +  +  G  + ++ST  +   T S     T    +  S+     
Sbjct: 878  TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937

Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435
             + S+    S T   + +    GS TT      +  +   T G+ ++T + +   + +  
Sbjct: 938  TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 997

Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460
               +++    + GS    V S++GT
Sbjct: 998  IEGSETTTVSSTGSETTTV-STTGT 1021



 Score = 57.8 bits (138), Expect = 8e-08
 Identities = 166/870 (19%), Positives = 303/870 (34%), Gaps = 96/870 (11%)

Query: 476  SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535
            S   T S   T + +S E TT+S     ++   T   + T  S+TGS     S+   ++T
Sbjct: 615  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 536  -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586
                   E  V    S   T S+  ++T ++S  GS +T     S+    +TT + T   
Sbjct: 675  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---TTSTEGSEITTASITG-S 730

Query: 587  KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646
            +T     EG         EGS      + G      ++  A  T++   + +     +  
Sbjct: 731  ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 784

Query: 647  SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706
            +S IG   +  + +S +  T   +N  ++    +  A++ +   TA    I       +T
Sbjct: 785  ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 707  TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766
            T + S  G         G+         ++      +  ET    T  + + T T  +E 
Sbjct: 843  TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 900

Query: 767  AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
            +ET TAS+    +TT            + +        S    +    S    +  ++V 
Sbjct: 901  SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 947

Query: 827  ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886
             + S T+ VS               EGS    +  + ++  +      E+    T     
Sbjct: 948  TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 887  GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946
               +   S  +  SS+     + S++G   T+TST     G +        S++ ++   
Sbjct: 994  TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAVYTT 1049

Query: 947  SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006
                  +   G     VS+          +  +      S   +   S    +     + 
Sbjct: 1050 GSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYIT 1109

Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTI-ETKSASVAPFTC 1065
              +      + S A        +++T +   T  T+ ++ +    T+ ET + S      
Sbjct: 1110 GSKTTTASTEGSEA------TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163

Query: 1066 KTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNE 1125
             TS A   E   T       + E +   +AS      T        T+T+   G +    
Sbjct: 1164 TTSSAAGSEATTT-------STEGSETTTASTAGSETTTASTAGSETTTASTAGSETT-- 1214

Query: 1126 EPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGA 1185
                        +  +  E ++  T     + PS   SE      F  G++T T A   +
Sbjct: 1215 -----------TASTSGSETNTACTTGSETSTPSSAGSE--TNTAFIIGSET-TIASTAS 1260

Query: 1186 AKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF----- 1240
             +P  + L  + S ++T + +A G    S+T SS   V T     S  P++++       
Sbjct: 1261 LEPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRT 1318

Query: 1241 -GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTS 1297
             G    +S+S ++    D   +  S T   +     G G S+   ++TTS  G   TT S
Sbjct: 1319 TGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGS 1378

Query: 1298 SSAGSSFVF-GTGPSAPSASPAFGANQTPT 1326
            +   +S  F  TGP +   +     + TPT
Sbjct: 1379 TREPTSSTFQETGPVSMGTN-TVSMSHTPT 1407



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 50/197 (25%), Positives = 80/197 (40%), Gaps = 29/197 (14%)

Query: 1277 PGASSNNTTTSGFGF---------GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327
            P A SN TT S  G            TTT+S+AGS     T PS   +     +      
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET---TTPSPTGSQTTIVSISGSEI 65

Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ-SAFGSG 1386
              +  A   N     + S +T     GS+    T G  S ++   + G + +  SA GS 
Sbjct: 66   TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG--SETTTVSITGTETTMVSAMGSE 123

Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446
            TT NS+++    S TT  +   +  + V T G+ ++T   +           +++ AA T
Sbjct: 124  TTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYTAD----------SETTAAST 169

Query: 1447 VGSNGKNVFSSSGTSFS 1463
             GS    VF++   + +
Sbjct: 170  TGSEMTTVFTAGSETIT 186


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 216/1057 (20%), Positives = 377/1057 (35%), Gaps = 116/1057 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            TSS     + +  E TT S     ++ A T   + T+ S+TGS M       V +  +  
Sbjct: 130  TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM-----TTVFTAGSET 184

Query: 540  LPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598
            + PS+ G  T +V  A +   + S++  E   +S+AH  TT  ST   +T      G   
Sbjct: 185  ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244

Query: 599  PAEI------------------LKEGSVLDILKSPGFASPKIDSVAAQPTATS------- 633
                                    E S      + GF +    +  ++PT  S       
Sbjct: 245  TVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETT 304

Query: 634  ------PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLS 687
                  P        SS  ++    G      S+   +T  +    ++    +   ++ S
Sbjct: 305  MASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETS 364

Query: 688  PRDT-------AKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPE 738
               T       A   G ET   S  G    + S TG       +  +    TC   ++  
Sbjct: 365  TDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMT 424

Query: 739  AIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWE 798
            A+     ET    T     +T+   S+S  T  ++  S T T  T G   K     GS  
Sbjct: 425  AVSTTVFETTTAST-EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSET 483

Query: 799  CSVC-----------------CVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS---L 837
             +                     S    +   VS   SE    S   S ++TV  +    
Sbjct: 484  TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 838  PSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSS---- 892
             +  + GLE      EGS   E+  V      T   + E +   T +   G +T++    
Sbjct: 544  TTVSTTGLETTTTSTEGS---EMTTVSTTGAETTTDSTEGSGT-TAASTAGSETTTVSTA 599

Query: 893  SSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKF---GDQGGFKIGVS---SDSGSINPM 946
             S N+ AS++     S+S++G   T  ST + +      +G     VS   S++  ++  
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 947  SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006
                  +   G     VS+      V  +         ++   +  VS T    G     
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTT----GSETTT 714

Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066
               +  E+  +S  G    T     +     +   SE  S+   G+  T +++ +  T  
Sbjct: 715  TSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTM 774

Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126
             S    E   A+  G     V  AS    +VF      E  +  + ST+           
Sbjct: 775  ASIMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAG 829

Query: 1127 PKCQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTAD 1182
             +  P  + G+  +  T  E S  +T S   S T  +  ES +   AT   G++T+T + 
Sbjct: 830  SETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTAST 888

Query: 1183 QGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGN 1242
            +G+     S    +  S +T A++ G  I   ST+ S    A+    +++   +  +   
Sbjct: 889  EGSETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELT 944

Query: 1243 TAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS 1302
            T  ++ S+++  S +    TT +T  + T      G+ +   +T+G     TTT+S  GS
Sbjct: 945  TVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGS 1001

Query: 1303 --SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPP 1360
              + V  TG    + S   G   T T  +    +     G    S +TA++ TGS+    
Sbjct: 1002 ETTTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE---- 1052

Query: 1361 TFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGAN 1420
            T  T +  S+        S++   S     +++    GS TT  +   +  + V+  G+ 
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 1421 SSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457
            ++T +     + +     +++  A T GS    VF++
Sbjct: 1113 TTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149



 Score = 94.4 bits (233), Expect = 7e-19
 Identities = 201/994 (20%), Positives = 377/994 (37%), Gaps = 100/994 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T++S   F  ++   T S P+  ++  + T       P +T           V +  +  
Sbjct: 274  TTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET 333

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599
            +  S++G   +     T   +GS +T   I+ S     T+ +ST   +T     EG    
Sbjct: 334  IRASTVGSETT-----TVSTTGSETTTASIMGSE----TSTDSTTGSETTTASTEGS-ET 383

Query: 600  AEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF-----SSSGIGFGE 654
                 EGS    + + G  +  +    ++ T T        A+S+      ++S  G   
Sbjct: 384  TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443

Query: 655  SLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-----SPRDTAKQTGIETPN--KSGKTT 707
            ++ + S  +  T   +   T     A    K      S   TA  TG+ET      G  T
Sbjct: 444  TIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDT 503

Query: 708  LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767
             +AS  G         G+         ++   +     ET    T      T T  +E +
Sbjct: 504  TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLE--TTTTSTEGS 561

Query: 768  ETMTASSSSCTVTT-GTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
            E  T S++    TT  T G G       GS   +V     ++E+    +  SE   +S  
Sbjct: 562  EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA--DSENTTASTADSETTSASTT 619

Query: 827  ASSSSTVPVSLPSGGSLGLEKFKKPEGSW-DCELCLVQNKADSTKCLACESAKPGTKSGF 885
             S ++T   +     +   E  +    S  D E  +V          + E ++  T S  
Sbjct: 620  GSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSA- 678

Query: 886  KGFDTSSSSSNSAASSSFKFGVSS---SSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGS 942
             G +T+ S+  S  ++    G  +   S++G   T TST         G +I  +S +GS
Sbjct: 679  TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTE--------GSEITTASITGS 730

Query: 943  --INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQF 1000
                  +EG + +    +     S+ +   E    S   + +  ++S + +  ++     
Sbjct: 731  ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSS-ETTMASIMGSETTMA---- 785

Query: 1001 GVSNLGQEEKKEELPKSSSAGF---SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS 1057
              S +G E  K     S        +  T + ++T +   T+ T+ ++      TI   +
Sbjct: 786  --STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE------TIPAST 837

Query: 1058 ASVAPFTCKTSEAKKEEMPATKGG-FSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSL 1116
            A     T  ++E  +    +T+G   +  + E +   +A+      T    +   T+T+ 
Sbjct: 838  AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897

Query: 1117 VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQ 1176
              G +      +   + +      T  E ++ ST     T  S + SE    +T   G++
Sbjct: 898  TEGSETTTASTEGSEITTVST---TGSETTTASTEGSETTTASTEGSELTTVSTT--GSE 952

Query: 1177 TSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVS 1236
            T T + +G+     + +     S +T A++AG      ST+ S    A+ + G  +  VS
Sbjct: 953  TITVSAEGSETTTVTTMG----SETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVS 1007

Query: 1237 SSAFGNTAESST-SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATT 1295
            S+    T  S+T +++ + S +    TT +T  + T  V+  G+ +  T+T G     TT
Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG---SETT 1064

Query: 1296 TSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGS 1355
            T S+ GS             + A  A+   T   + G+        GS   +T ++ TGS
Sbjct: 1065 TVSTTGSE-----------TTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGS 1111

Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415
            +       T ++S++        S++   S T+  +++A   GS  T    T +  + V 
Sbjct: 1112 K-------TTTASTEG-------SEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVS 1157

Query: 1416 TFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGS 1449
            T G+ ++T +A+   + +     +++  A T GS
Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAGS 1191



 Score = 88.6 bits (218), Expect = 4e-17
 Identities = 188/993 (18%), Positives = 361/993 (36%), Gaps = 105/993 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T S   T +    E +T S +   ++ A T   + T+ S+ GS     S+   ++T  ++
Sbjct: 349  TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598
                +     +    + +E++  S+T+ E   +S+     T+ ST+  +T     EG   
Sbjct: 409  TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 462

Query: 599  PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658
               +   GS      + G  +    +   + T     V+T   I S +++    G    A
Sbjct: 463  TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 515

Query: 659  GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716
             S+   +   +  + ++N  ++   ++ +   T   TG+ET   S  G    + S TG  
Sbjct: 516  VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 572

Query: 717  DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776
                   G+         ++   +     E     T      T +  +  +ET TAS++S
Sbjct: 573  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 630

Query: 777  CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836
               TT +           GS   +V   + ++E     +  SE+  +S   S ++TV  +
Sbjct: 631  SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 679

Query: 837  LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896
                   G E     EGS    + +  ++         E+    T+       + + S  
Sbjct: 680  -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 897  SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956
            + AS+      ++S+ G   T  ST     G +       SS++   + M      +  I
Sbjct: 733  TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 788

Query: 957  GDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPK 1016
            G     VS+ S           +N +  ++S  ++  +       VS  G E     +P 
Sbjct: 789  GSETTKVSTASSKMTTVF---TENSETTIASTTASETTT------VSTAGSET----IPA 835

Query: 1017 SSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMP 1076
            S++      T    ST     T  ++E   +    T  +++ +      +T+ A  E   
Sbjct: 836  STAGS---ETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSE 892

Query: 1077 ATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKK---ADNEEPKCQPVF 1133
             T           AS   + +  +  T  +     T+T+   G +   A  E  +   V 
Sbjct: 893  TTTTSTEGSETTTASTEGSEITTVSTTGSE-----TTTASTEGSETTTASTEGSELTTVS 947

Query: 1134 SFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAF--GAQTSTTADQGAAKPVFS 1191
            + G+   T     S++T   +M   +   S   ++ T     G++T+T + +G+     S
Sbjct: 948  TTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVS 1007

Query: 1192 FLNN-----SSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246
               +     S++ + T  TS  G    + T++ +   A +  G  +   S+     T  S
Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVS 1067

Query: 1247 STSQSLLFSQDSKL-----------ATTSSTGTAVTPFVFGPGA---------------- 1279
            +T      +  + L            TT+ST  + T  V+  G+                
Sbjct: 1068 TTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1280 --SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPN 1337
              SS  TT S  G   TT  ++   +    T  S  + S A G+  T T  +    +  +
Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS 1187

Query: 1338 PPGFGSISSSTA--LFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAF 1395
              G  + ++STA     T S     T    +S S+        S+++  S     +++AF
Sbjct: 1188 TAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAF 1247

Query: 1396 QFGSSTTNFNFTNNSPSGVFTFGANSSTPAASA 1428
              GS TT  +  +  P+     G+ ++T + +A
Sbjct: 1248 IIGSETTIASTASLEPTATSLTGSETTTVSITA 1280



 Score = 85.1 bits (209), Expect = 5e-16
 Identities = 157/800 (19%), Positives = 285/800 (35%), Gaps = 65/800 (8%)

Query: 691  TAKQTGIETP-NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749
            TA   G ET  + +G  T + S TG        +G+         ++         ET  
Sbjct: 87   TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146

Query: 750  PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809
              T      T T  +  +ET  AS++   +TT      +         E +   VS    
Sbjct: 147  VSTVGSE--TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTT--VSTAGS 202

Query: 810  DNKCVSCMSEKPGSSVPASSSSTVPVSLPSG----GSLGLEKFKKPEGSWDCELCLVQNK 865
            +   VS    +  ++  A S +T   ++ S      + G E      GS   E      +
Sbjct: 203  ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---ETTAASTE 259

Query: 866  ADSTKCLACESAKPGTKSGFKGFDTSSSSSNSA----ASSSFKFGVSSSSSGPSQTLTST 921
               T     E +K  T S   GF+T+++S+  +    AS+       +S+ GP  T  ST
Sbjct: 260  DSETNTAFTEDSKTTTAST-TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVST 318

Query: 922  GN------FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975
             +      F  G +      V S++ +++        +  +G      S+          
Sbjct: 319  ASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTAST 378

Query: 976  SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035
              ++          +  VS T  +    ++   E      + S       T    +T + 
Sbjct: 379  EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438

Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095
              + +T  + S     T  T+ +     T   SE K     A   G          L + 
Sbjct: 439  EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT----AYTTGSETTTASNTGLETT 494

Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK-----DENSSKST 1150
            +VF +G          + T+ V    ++          S   SE T       E ++ ST
Sbjct: 495  TVFTIGSDTTTASTEGSETTAVSATGSE------MTTVSTEGSENTTVSTTGSETTTVST 548

Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210
                 T  S + SE    +T   GA+T+T + +G              S +T A++AG  
Sbjct: 549  TGLETTTTSTEGSEMTTVSTT--GAETTTDSTEG--------------SGTTAASTAGSE 592

Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV 1270
                ST+ S    A+    ++++  ++ +   TA +++S++   S +    TT ST  + 
Sbjct: 593  TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652

Query: 1271 TPFVFGPGA--------SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGAN 1322
            T  V   G+         S  TT S  G   T ++  +G++ V  TG      S   G+ 
Sbjct: 653  TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-GSE 711

Query: 1323 QTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380
             T T  +    +  +  G  + ++ST  +   T S     T    ++ S+        S+
Sbjct: 712  TTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771

Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440
            +   S     ++ A   GS TT  +  ++  + VFT  + ++  + +A  + +     ++
Sbjct: 772  TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 1441 SPAAFTVGSNGKNVFSSSGT 1460
            +  A T GS      S+ G+
Sbjct: 832  TIPASTAGSETTTTTSTEGS 851



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 219/1063 (20%), Positives = 383/1063 (36%), Gaps = 157/1063 (14%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T S   T + +  E TT+       +   T   + T+ S+ GS +   S+   ++T A+ 
Sbjct: 399  TGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTAST 458

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSST------LEPIISSSAHHVTTVNSTNCKKTPPEDC 593
                +   T +    KTA  +GS +T      LE     +    TT  ST   +T     
Sbjct: 459  EGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSA 518

Query: 594  EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSP-------VVYTRPAISSFS 646
             G      +  EGS    + + G  +  + +   + T TS        V  T    ++ S
Sbjct: 519  TGS-EMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDS 577

Query: 647  SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706
            + G G   +  AGS    +T  +    ++N   +   ++ +   +A  TG ET   S  +
Sbjct: 578  TEGSGTTAASTAGS----ETTTVSTADSENTTASTADSETT---SASTTGSETTTASTTS 630

Query: 707  TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766
            + + + +  G +    + T D +T +V                  T  +R +T T   E 
Sbjct: 631  SETTTASTEGSE-TTTVSTTDSETTMVST----------------TGSERTITST---EG 670

Query: 767  AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSN-----NAEDNKCVSCM---S 818
            +ET T S++    T  T G G       GS    V    +     + E ++  +     S
Sbjct: 671  SETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGS 730

Query: 819  EKPGSSVPASSSSTVPVS---LPSGGSLGLEKFKKPEGSWDCELCLVQ-NKADSTKCLAC 874
            E   +S   S ++T         S  + G E       S +  +  +  ++      +  
Sbjct: 731  ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGS 790

Query: 875  ESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSG----PSQTLTSTGNFKFGDQG 930
            E+ K  T S       + +S  + AS++     + S++G    P+ T  S        +G
Sbjct: 791  ETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEG 850

Query: 931  GFKIGVS---SDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSS 987
                  S   S++ + +  S     +  IG      S+E           ++        
Sbjct: 851  SETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG 910

Query: 988  GLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVT--SENK 1045
                 VS T    G        +  E   +S+ G    T  +++T +   T+    SE  
Sbjct: 911  SEITTVSTT----GSETTTASTEGSETTTASTEGSELTT--VSTTGSETITVSAEGSETT 964

Query: 1046 SSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGR--- 1102
            +   +G+  T +++    T   S A  E   A+  G     V      + +V   G    
Sbjct: 965  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024

Query: 1103 ---TEEKQQEPVTS----TSLVFGKKADN-----EEPKCQPVFSFGNSEQTKD----ENS 1146
               TE  +   VT+    T+ V+   ++      E  +   V + G+   T      E +
Sbjct: 1025 ITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084

Query: 1147 SKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPAT- 1205
            + ST     T  S   SE      +  G++T+T + +G+     S  ++ ++++ST  + 
Sbjct: 1085 TVSTSGSGTTTASTAGSE--TTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSE 1142

Query: 1206 ----------SAGGGIFGS--STSSSNPPVATFVFGQSSNPVSSSAFGN-TAESSTSQSL 1252
                      +      GS  +TSS+    AT    + S   ++S  G+ T  +ST+ S 
Sbjct: 1143 MTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS- 1201

Query: 1253 LFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS----SFVFG- 1307
                     TT+ST  + T      G+ +N   T+G     T+T SSAGS    +F+ G 
Sbjct: 1202 -------ETTTASTAGSETTTASTSGSETNTACTTG---SETSTPSSAGSETNTAFIIGS 1251

Query: 1308 ------TGPSAPSASPAFGANQTPTFGQSQGAS---------------------QP--NP 1338
                  T    P+A+   G+  T     + GA+                     QP  N 
Sbjct: 1252 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNT 1311

Query: 1339 PGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFG 1398
            P  G+ ++ T L  + S    P     +S++   V G   + S  G+ T   SS+    G
Sbjct: 1312 PMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHG 1371

Query: 1399 SSTTNFNFTNNSPS-----GVFTFGAN----SSTPAASAQPSG 1432
              TT  +    + S     G  + G N    S TP    +PSG
Sbjct: 1372 VRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPSG 1414



 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 193/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%)

Query: 478  PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537
            P   S+  T + +  E TT       ++ A T   + T+PS TGS     S    + T  
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 68

Query: 538  NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582
            +     +   + +     TA ++GS +T+               E  + S+    TT NS
Sbjct: 69   STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS 128

Query: 583  TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642
            T   +T      G         E + +  + S    +   DS     + T   + T    
Sbjct: 129  TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 643  SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702
             S + +    G      S+   +T  +    ++    +   ++ +   T      +    
Sbjct: 181  GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 240

Query: 703  SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758
              +TT+S +G+           T D +T       +K         ET    T   +  +
Sbjct: 241  GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295

Query: 759  TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810
              T+ SE+        ET   S++S  VTT      +  +   +GS       VS    +
Sbjct: 296  ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 352

Query: 811  NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869
                S M SE    S   S ++T         +   E  +    S         +  DS 
Sbjct: 353  TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412

Query: 870  KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923
                C      T      F+T+++S+       A++S  +   +S+    + T+T+ G+ 
Sbjct: 413  TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 472

Query: 924  FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979
             K     G +   +S++G    ++  +      +   G     VS+            ++
Sbjct: 473  TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532

Query: 980  NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039
            N     +   +  VS T    G+       +  E+   S+ G    T   +ST     T 
Sbjct: 533  NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 585

Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099
             ++    +  + T ++++ + +    +T+ A       T    +      AS   +    
Sbjct: 586  ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 645

Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156
            +  T+   +  + ST+         E  +   V + G+      E S  +T S +    T
Sbjct: 646  VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 703

Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208
            K S   SE    +T           G++T+T + +G+     S    +  S +T A++ G
Sbjct: 704  KVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 759

Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265
                 +ST+SS   +A+ +   S   ++S+    T + ST+ S    +F+++S+    S+
Sbjct: 760  SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817

Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317
            T        TA +  +    A S  TTT+      TTT+S+ GS +    T  S  + + 
Sbjct: 818  TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877

Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375
              G+  T    +    +  +  G  + ++ST  +   T S     T    +  S+     
Sbjct: 878  TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937

Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435
             + S+    S T   + +    GS TT      +  +   T G+ ++T + +   + +  
Sbjct: 938  TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 997

Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460
               +++    + GS    V S++GT
Sbjct: 998  IEGSETTTVSSTGSETTTV-STTGT 1021



 Score = 57.8 bits (138), Expect = 8e-08
 Identities = 166/870 (19%), Positives = 303/870 (34%), Gaps = 96/870 (11%)

Query: 476  SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535
            S   T S   T + +S E TT+S     ++   T   + T  S+TGS     S+   ++T
Sbjct: 615  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 536  -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586
                   E  V    S   T S+  ++T ++S  GS +T     S+    +TT + T   
Sbjct: 675  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---TTSTEGSEITTASITG-S 730

Query: 587  KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646
            +T     EG         EGS      + G      ++  A  T++   + +     +  
Sbjct: 731  ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 784

Query: 647  SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706
            +S IG   +  + +S +  T   +N  ++    +  A++ +   TA    I       +T
Sbjct: 785  ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 707  TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766
            T + S  G         G+         ++      +  ET    T  + + T T  +E 
Sbjct: 843  TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 900

Query: 767  AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
            +ET TAS+    +TT            + +        S    +    S    +  ++V 
Sbjct: 901  SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 947

Query: 827  ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886
             + S T+ VS               EGS    +  + ++  +      E+    T     
Sbjct: 948  TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 887  GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946
               +   S  +  SS+     + S++G   T+TST     G +        S++ ++   
Sbjct: 994  TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAVYTT 1049

Query: 947  SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006
                  +   G     VS+          +  +      S   +   S    +     + 
Sbjct: 1050 GSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYIT 1109

Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTI-ETKSASVAPFTC 1065
              +      + S A        +++T +   T  T+ ++ +    T+ ET + S      
Sbjct: 1110 GSKTTTASTEGSEA------TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163

Query: 1066 KTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNE 1125
             TS A   E   T       + E +   +AS      T        T+T+   G +    
Sbjct: 1164 TTSSAAGSEATTT-------STEGSETTTASTAGSETTTASTAGSETTTASTAGSETT-- 1214

Query: 1126 EPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGA 1185
                        +  +  E ++  T     + PS   SE      F  G++T T A   +
Sbjct: 1215 -----------TASTSGSETNTACTTGSETSTPSSAGSE--TNTAFIIGSET-TIASTAS 1260

Query: 1186 AKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF----- 1240
             +P  + L  + S ++T + +A G    S+T SS   V T     S  P++++       
Sbjct: 1261 LEPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRT 1318

Query: 1241 -GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTS 1297
             G    +S+S ++    D   +  S T   +     G G S+   ++TTS  G   TT S
Sbjct: 1319 TGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGS 1378

Query: 1298 SSAGSSFVF-GTGPSAPSASPAFGANQTPT 1326
            +   +S  F  TGP +   +     + TPT
Sbjct: 1379 TREPTSSTFQETGPVSMGTN-TVSMSHTPT 1407



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 50/197 (25%), Positives = 80/197 (40%), Gaps = 29/197 (14%)

Query: 1277 PGASSNNTTTSGFGF---------GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327
            P A SN TT S  G            TTT+S+AGS     T PS   +     +      
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET---TTPSPTGSQTTIVSISGSEI 65

Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ-SAFGSG 1386
              +  A   N     + S +T     GS+    T G  S ++   + G + +  SA GS 
Sbjct: 66   TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG--SETTTVSITGTETTMVSAMGSE 123

Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446
            TT NS+++    S TT  +   +  + V T G+ ++T   +           +++ AA T
Sbjct: 124  TTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYTAD----------SETTAAST 169

Query: 1447 VGSNGKNVFSSSGTSFS 1463
             GS    VF++   + +
Sbjct: 170  TGSEMTTVFTAGSETIT 186


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 207/1055 (19%), Positives = 376/1055 (35%), Gaps = 112/1055 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            TSS     + +  E TT S     ++ A T   + T+ S+TGS M    + +  +    +
Sbjct: 130  TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM----TTVFTAGSETI 185

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599
             P ++   T +V  A +   + S++  E   +S+AH  TT  ST   +T      G    
Sbjct: 186  TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 600  AE------------------ILKEGSVLDILKSPGFASPKIDSVAAQPTATS-------- 633
                                   E S      + GF +    +  ++PT  S        
Sbjct: 246  VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTM 305

Query: 634  -----PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-- 686
                 P        SS  ++    G      S+   +T  +    ++    +   ++   
Sbjct: 306  ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365

Query: 687  -----SPRDTAKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEA 739
                 S   TA   G ET   S  G    + S TG       +  +    TC   ++  A
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 740  IKCVACETPKPGT------------------CVKRALTLTVVSESAETMTA-SSSSCTVT 780
            +     ET    T                    + + T TV +  +ET TA ++ S T T
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485

Query: 781  TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS--- 836
                G        IGS        S    +   VS   SE    S   S ++TV  +   
Sbjct: 486  ASNTGLETTTVFTIGS---DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSE 542

Query: 837  LPSGGSLGLE-KFKKPEGS-------WDCELCLVQNKADSTKCLACESAKPGTKSGFKGF 888
              +  + GLE      EGS          E      +   T   +   ++  T S     
Sbjct: 543  TTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSE 602

Query: 889  DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE 948
            +T++S+++S  +S+   G  ++++  + + T+T + + G +        S++  ++    
Sbjct: 603  NTTASTADSETTSASTTGSETTTASTTSSETTTASTE-GSETTTVSTTDSETTMVSTTGS 661

Query: 949  GFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQE 1008
                +   G     VS+      V  +         ++   +  VS T    G       
Sbjct: 662  ERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTT----GSETTTTS 716

Query: 1009 EKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTS 1068
             +  E+  +S  G    T     +     +   SE  S+   G+  T +++ +  T   S
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 1069 EAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPK 1128
                E   A+  G     V  AS    +VF      E  +  + ST+            +
Sbjct: 777  IMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAGSE 831

Query: 1129 CQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTADQG 1184
              P  + G+  +  T  E S  +T S   S T  +  ES +   AT   G++T+T + +G
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTASTEG 890

Query: 1185 AAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTA 1244
            +     S    +  S +T A++ G  I   ST+ S    A+    +++   +  +   T 
Sbjct: 891  SETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTV 946

Query: 1245 ESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-- 1302
             ++ S+++  S +    TT +T  + T      G+ +   +T+G     TTT+S  GS  
Sbjct: 947  STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGSET 1003

Query: 1303 SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF 1362
            + V  TG    + S   G   T T  +    +     G    S +TA++ TGS+    T 
Sbjct: 1004 TTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE----TT 1054

Query: 1363 GTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS 1422
             T +  S+        S++   S     +++    GS TT  +   +  + V+  G+ ++
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114

Query: 1423 TPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457
            T +     + +     +++  A T GS    VF++
Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 191/1007 (18%), Positives = 371/1007 (36%), Gaps = 107/1007 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T S   T +    E +T S +   ++ A T   + T+ S+ GS     S+   ++T  ++
Sbjct: 349  TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598
                +     +    + +E++  S+T+ E   +S+     T+ ST+  +T     EG   
Sbjct: 409  TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 462

Query: 599  PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658
               +   GS      + G  +    +   + T     V+T   I S +++    G    A
Sbjct: 463  TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 515

Query: 659  GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716
             S+   +   +  + ++N  ++   ++ +   T   TG+ET   S  G    + S TG  
Sbjct: 516  VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 572

Query: 717  DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776
                   G+         ++   +     E     T      T +  +  +ET TAS++S
Sbjct: 573  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 630

Query: 777  CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836
               TT +           GS   +V   + ++E     +  SE+  +S   S ++TV  +
Sbjct: 631  SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 679

Query: 837  LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896
                   G E     EGS    + +  ++         E+    T+       + + S  
Sbjct: 680  -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSET 732

Query: 897  SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956
            + AS+      ++S+ G   T  ST     G +       SS++   + M      +  I
Sbjct: 733  TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 788

Query: 957  GDFKFGVSS-ESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELP 1015
            G     VS+  SK   V  ++         +S  +   +        S  G E       
Sbjct: 789  GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT--- 845

Query: 1016 KSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEM 1075
             +S+ G    T     +     +  +SE  ++  +G+  T +++    T  TS    E  
Sbjct: 846  -TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 1076 PATKGGFSFGNVEPASLPSASVFVLGR------TEEKQQEPVTST-SLVFGKKADNEEPK 1128
             A+  G     V      + +    G       TE  +   V++T S      A+  E  
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 1129 CQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATF--AFGAQTSTTADQGAA 1186
               V + G+   T     S++T   +    +   S + ++ T   + G++T+T +  G  
Sbjct: 965  T--VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1022

Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246
              + S    +  S +T  T+AG       T+ S     +    +++   ++ +   TA +
Sbjct: 1023 TTITS----TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078

Query: 1247 STSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVF 1306
            +  ++   S      TT+ST  + T  V+  G  S  TT S  G  ATT S+++      
Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSETTTVYITG--SKTTTASTEGSEATTVSTTS------ 1130

Query: 1307 GTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVS 1366
                S  + +   G+  T                F ++S +T +   GS+    +     
Sbjct: 1131 ----SETTTASTTGSEMTTV--------------FTTVSETTTVSTIGSEATTSSAAGSE 1172

Query: 1367 SSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAA 1426
            +++      +  + S  GS TT  S++    GS TT  + + +  +   T G+ +STP++
Sbjct: 1173 ATTTSTEGSETTTASTAGSETTTASTA----GSETTTASTSGSETNTACTTGSETSTPSS 1228

Query: 1427 SAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSS----GTSFSGRKIKT 1469
            +           +++  AF +GS      ++S     TS +G +  T
Sbjct: 1229 AG----------SETNTAFIIGSESTIASTASLEPTATSLTGSETTT 1265



 Score = 85.1 bits (209), Expect = 5e-16
 Identities = 157/800 (19%), Positives = 285/800 (35%), Gaps = 65/800 (8%)

Query: 691  TAKQTGIETP-NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749
            TA   G ET  + +G  T + S TG        +G+         ++         ET  
Sbjct: 87   TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146

Query: 750  PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809
              T      T T  +  +ET  AS++   +TT      +         E +   VS    
Sbjct: 147  VSTVGSE--TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTT--VSTAGS 202

Query: 810  DNKCVSCMSEKPGSSVPASSSSTVPVSLPSG----GSLGLEKFKKPEGSWDCELCLVQNK 865
            +   VS    +  ++  A S +T   ++ S      + G E      GS   E      +
Sbjct: 203  ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---ETTAASTE 259

Query: 866  ADSTKCLACESAKPGTKSGFKGFDTSSSSSNSA----ASSSFKFGVSSSSSGPSQTLTST 921
               T     E +K  T S   GF+T+++S+  +    AS+       +S+ GP  T  ST
Sbjct: 260  DSETNTAFTEDSKTTTAST-TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVST 318

Query: 922  GN------FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975
             +      F  G +      V S++ +++        +  +G      S+          
Sbjct: 319  ASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTAST 378

Query: 976  SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035
              ++          +  VS T  +    ++   E      + S       T    +T + 
Sbjct: 379  EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438

Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095
              + +T  + S     T  T+ +     T   SE K     A   G          L + 
Sbjct: 439  EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT----AYTTGSETTTASNTGLETT 494

Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK-----DENSSKST 1150
            +VF +G          + T+ V    ++          S   SE T       E ++ ST
Sbjct: 495  TVFTIGSDTTTASTEGSETTAVSATGSE------MTTVSTEGSENTTVSTTGSETTTVST 548

Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210
                 T  S + SE    +T   GA+T+T + +G              S +T A++AG  
Sbjct: 549  TGLETTTTSTEGSEMTTVSTT--GAETTTDSTEG--------------SGTTAASTAGSE 592

Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV 1270
                ST+ S    A+    ++++  ++ +   TA +++S++   S +    TT ST  + 
Sbjct: 593  TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652

Query: 1271 TPFVFGPGA--------SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGAN 1322
            T  V   G+         S  TT S  G   T ++  +G++ V  TG      S   G+ 
Sbjct: 653  TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-GSE 711

Query: 1323 QTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380
             T T  +    +  +  G  + ++ST  +   T S     T    ++ S+        S+
Sbjct: 712  TTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771

Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440
            +   S     ++ A   GS TT  +  ++  + VFT  + ++  + +A  + +     ++
Sbjct: 772  TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 1441 SPAAFTVGSNGKNVFSSSGT 1460
            +  A T GS      S+ G+
Sbjct: 832  TIPASTAGSETTTTTSTEGS 851



 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 193/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%)

Query: 478  PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537
            P   S+  T + +  E TT       ++ A T   + T+PS TGS     S    + T  
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 68

Query: 538  NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582
            +     +   + +     TA ++GS +T+               E  + S+    TT NS
Sbjct: 69   STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS 128

Query: 583  TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642
            T   +T      G         E + +  + S    +   DS     + T   + T    
Sbjct: 129  TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 643  SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702
             S + +    G      S+   +T  +    ++    +   ++ +   T      +    
Sbjct: 181  GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 240

Query: 703  SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758
              +TT+S +G+           T D +T       +K         ET    T   +  +
Sbjct: 241  GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295

Query: 759  TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810
              T+ SE+        ET   S++S  VTT      +  +   +GS       VS    +
Sbjct: 296  ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 352

Query: 811  NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869
                S M SE    S   S ++T         +   E  +    S         +  DS 
Sbjct: 353  TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412

Query: 870  KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923
                C      T      F+T+++S+       A++S  +   +S+    + T+T+ G+ 
Sbjct: 413  TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 472

Query: 924  FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979
             K     G +   +S++G    ++  +      +   G     VS+            ++
Sbjct: 473  TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532

Query: 980  NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039
            N     +   +  VS T    G+       +  E+   S+ G    T   +ST     T 
Sbjct: 533  NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 585

Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099
             ++    +  + T ++++ + +    +T+ A       T    +      AS   +    
Sbjct: 586  ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 645

Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156
            +  T+   +  + ST+         E  +   V + G+      E S  +T S +    T
Sbjct: 646  VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 703

Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208
            K S   SE    +T           G++T+T + +G+     S    +  S +T A++ G
Sbjct: 704  KVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 759

Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265
                 +ST+SS   +A+ +   S   ++S+    T + ST+ S    +F+++S+    S+
Sbjct: 760  SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817

Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317
            T        TA +  +    A S  TTT+      TTT+S+ GS +    T  S  + + 
Sbjct: 818  TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877

Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375
              G+  T    +    +  +  G  + ++ST  +   T S     T    +  S+     
Sbjct: 878  TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937

Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435
             + S+    S T   + +    GS TT      +  +   T G+ ++T + +   + +  
Sbjct: 938  TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 997

Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460
               +++    + GS    V S++GT
Sbjct: 998  IEGSETTTVSSTGSETTTV-STTGT 1021



 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 189/936 (20%), Positives = 323/936 (34%), Gaps = 102/936 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTE--- 536
            T S + T +    E TT S +   ++   T  ++ T+ S+ GS M   S+   ++T    
Sbjct: 519  TGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST 578

Query: 537  --ANVLPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDC 593
              +     S+ G  T +V  A +   + S++  E   +S+    TT  ST   +T     
Sbjct: 579  EGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAST 638

Query: 594  EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSS----G 649
            EG      +    S   ++ + G +   I S     T T     +   +S+  S      
Sbjct: 639  EGS-ETTTVSTTDSETTMVSTTG-SERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696

Query: 650  IGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTT 707
            I   E+ K  ++    T       T+   I   +   S   TA   G ET   S  G  T
Sbjct: 697  ITGSETTKVSTTGSETT----TTSTEGSEITTASITGSETTTASTEGSETTTASTEGSET 752

Query: 708  LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767
             SAS TG          +      ++ ++      +  ET K  T   +  T  V +E++
Sbjct: 753  TSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT--VFTENS 810

Query: 768  ETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPA 827
            ET  AS+++   TT +    +         E +    +  +E     +  SE   +S  +
Sbjct: 811  ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTES 870

Query: 828  SSSSTVPVSLPSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886
            S ++T         ++G E      EGS   E      +   T   + E ++  T S   
Sbjct: 871  SETTTAT-------TIGSETTTASTEGS---ETTTTSTEGSETTTASTEGSEITTVS--- 917

Query: 887  GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS---SDSGSI 943
                ++ S  + AS+      ++S+ G   T  ST        G   I VS   S++ ++
Sbjct: 918  ----TTGSETTTASTEGSETTTASTEGSELTTVST-------TGSETITVSAEGSETTTV 966

Query: 944  NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVS 1003
              M      +   G     VS+            ++      +   +  VS T  +  ++
Sbjct: 967  TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTIT 1026

Query: 1004 NLGQEEKKEELPKSSSAGFSFGTG---VINSTPAPANTIVTSENKSSFNLGTIETKSASV 1060
            +    E        S     + TG      ST     T V++    +    T + ++ +V
Sbjct: 1027 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTV 1086

Query: 1061 APFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS---LV 1117
            +     T+ A       T    +      AS   +    +  T  +     T+ S    V
Sbjct: 1087 STSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146

Query: 1118 FGKKADNEEPKC----QPVFSFGNSEQTK-----DENSSKSTFSFSMTKPSEKESEQPAK 1168
            F   ++              S   SE T       E ++ ST     T  S   SE    
Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTA 1206

Query: 1169 ATFAF--------GAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSN 1220
            +T           G++TST +  G+       + + S+ +ST               +S 
Sbjct: 1207 STSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIAST---------------ASL 1251

Query: 1221 PPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGAS 1280
             P AT + G  +  VS +A G TA S+T  S  F        T +T  ++ P    P + 
Sbjct: 1252 EPTATSLTGSETTTVSITASGATAASTTVSSTTF------VLTKATDVSIQPITNTPMSG 1305

Query: 1281 SNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPG 1340
            +  T     G   T +SS   +  +  T  +A    P    N +     + GAS      
Sbjct: 1306 TRTT-----GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAH 1360

Query: 1341 FGSISSSTALFPTGS---QPAPPTFG--TVSSSSQP 1371
                ++ +   PT S   +  P + G  TVS S  P
Sbjct: 1361 GVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTP 1396



 Score = 54.3 bits (129), Expect = 9e-07
 Identities = 165/869 (18%), Positives = 302/869 (34%), Gaps = 104/869 (11%)

Query: 476  SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535
            S   T S   T + +S E TT+S     ++   T   + T  S+TGS     S+   ++T
Sbjct: 615  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 536  -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586
                   E  V    S   T S+  ++T ++S  GS +T     S+    +TT + T   
Sbjct: 675  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---TTSTEGSEITTASITG-S 730

Query: 587  KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646
            +T     EG         EGS      + G      ++  A  T++   + +     +  
Sbjct: 731  ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 784

Query: 647  SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706
            +S IG   +  + +S +  T   +N  ++    +  A++ +   TA    I       +T
Sbjct: 785  ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 707  TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766
            T + S  G         G+         ++      +  ET    T  + + T T  +E 
Sbjct: 843  TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 900

Query: 767  AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
            +ET TAS+    +TT            + +        S    +    S    +  ++V 
Sbjct: 901  SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 947

Query: 827  ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886
             + S T+ VS               EGS    +  + ++  +      E+    T     
Sbjct: 948  TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 887  GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946
               +   S  +  SS+     + S++G   T+TST     G +        S++ ++   
Sbjct: 994  TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAV--- 1046

Query: 947  SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006
                          +   SE+     +          G  +  ++   L       S  G
Sbjct: 1047 --------------YTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066
                     ++++    + TG   +T +   +  T+ + +S    T  T  + +      
Sbjct: 1093 TTTASTAGSETTTV---YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149

Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126
             SE        T    + G+    S  + S      TE  +    T+T+   G +     
Sbjct: 1150 VSE--------TTTVSTIGSEATTSSAAGSEATTTSTEGSE----TTTASTAGSETTTAS 1197

Query: 1127 PKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAA 1186
                   +   S     E ++  T     + PS   SE      F  G++ ST A   + 
Sbjct: 1198 TAGSETTTASTS---GSETNTACTTGSETSTPSSAGSE--TNTAFIIGSE-STIASTASL 1251

Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF------ 1240
            +P  + L  + S ++T + +A G    S+T SS   V T     S  P++++        
Sbjct: 1252 EPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1309

Query: 1241 GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTSS 1298
            G    +S+S ++    D   +  S T   +     G G S+   ++TTS  G   TT S+
Sbjct: 1310 GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369

Query: 1299 SAGSSFVF-GTGPSAPSASPAFGANQTPT 1326
               +S  F  TGP +   +     + TPT
Sbjct: 1370 REPTSSTFQETGPVSMGTN-TVSMSHTPT 1397



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 50/197 (25%), Positives = 80/197 (40%), Gaps = 29/197 (14%)

Query: 1277 PGASSNNTTTSGFGF---------GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327
            P A SN TT S  G            TTT+S+AGS     T PS   +     +      
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET---TTPSPTGSQTTIVSISGSEI 65

Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ-SAFGSG 1386
              +  A   N     + S +T     GS+    T G  S ++   + G + +  SA GS 
Sbjct: 66   TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG--SETTTVSITGTETTMVSAMGSE 123

Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446
            TT NS+++    S TT  +   +  + V T G+ ++T   +           +++ AA T
Sbjct: 124  TTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYTAD----------SETTAAST 169

Query: 1447 VGSNGKNVFSSSGTSFS 1463
             GS    VF++   + +
Sbjct: 170  TGSEMTTVFTAGSETIT 186


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
            sapiens]
          Length = 1521

 Score = 99.0 bits (245), Expect = 3e-20
 Identities = 206/1055 (19%), Positives = 379/1055 (35%), Gaps = 112/1055 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            TSS     + +  E TT S     ++ A T   + T+ S+TGS M    + +  +    +
Sbjct: 130  TSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM----TTVFTAGSETI 185

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599
             P ++   T +V  A +   + S++  E   +S+AH  TT  ST   +T      G    
Sbjct: 186  TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 600  AE------------------ILKEGSVLDILKSPGFASPKIDSVAAQPTATS-------- 633
                                   E S      + GF +    +  ++PT  S        
Sbjct: 246  VSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTM 305

Query: 634  -----PVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-- 686
                 P        SS  ++    G      S+   +T  +    ++    +   ++   
Sbjct: 306  ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365

Query: 687  -----SPRDTAKQTGIETPNKS--GKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEA 739
                 S   TA   G ET   S  G    + S TG       +  +    TC   ++  A
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 740  IKCVACETPKPGT------------------CVKRALTLTVVSESAETMTA-SSSSCTVT 780
            +     ET    T                    + + T TV +  +ET TA ++ S T T
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT 485

Query: 781  TGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCM-SEKPGSSVPASSSSTVPVS--- 836
                G        IGS        S    +   VS   SE    S   S ++TV  +   
Sbjct: 486  ASNTGLETTTVFTIGS---DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSE 542

Query: 837  LPSGGSLGLE-KFKKPEGS-------WDCELCLVQNKADSTKCLACESAKPGTKSGFKGF 888
              +  + GLE      EGS          E      +   T   +   ++  T S     
Sbjct: 543  TTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSE 602

Query: 889  DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE 948
            +T++S+++S  +S+   G  ++++  + + T+T + + G +        S++  ++    
Sbjct: 603  NTTASTADSETTSASTTGSETTTASTTSSETTTASTE-GSETTTVSTTDSETTMVSTTGS 661

Query: 949  GFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQE 1008
                +   G     VS+      V  +         ++   +  VS T  +  +++    
Sbjct: 662  ERTITSTEGSETTTVSATGSETTVSTEGSGTT-TVSITGSETTKVSTTGSETTITS---- 716

Query: 1009 EKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTS 1068
             +  E+  +S  G    T     +     +   SE  S+   G+  T +++ +  T   S
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 1069 EAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPK 1128
                E   A+  G     V  AS    +VF      E  +  + ST+            +
Sbjct: 777  IMGSETTMASTIGSETTKVSTASSKMTTVFT-----ENSETTIASTTASETTTVSTAGSE 831

Query: 1129 CQPVFSFGN--SEQTKDENSSKSTFSF--SMTKPSEKESEQPAKATFAFGAQTSTTADQG 1184
              P  + G+  +  T  E S  +T S   S T  +  ES +   AT   G++T+T + +G
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT-TIGSETTTASTEG 890

Query: 1185 AAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTA 1244
            +     S    +  S +T A++ G  I   ST+ S    A+    +++   +  +   T 
Sbjct: 891  SETTTTS----TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTV 946

Query: 1245 ESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-- 1302
             ++ S+++  S +    TT +T  + T      G+ +   +T+G     TTT+S  GS  
Sbjct: 947  STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAG---SETTTASIEGSET 1003

Query: 1303 SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTF 1362
            + V  TG    + S   G   T T  +    +     G    S +TA++ TGS+    T 
Sbjct: 1004 TTVSSTGSETTTVSTT-GTETTITSTEGSETTTVTTAG----SETTAVYTTGSE----TT 1054

Query: 1363 GTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS 1422
             T +  S+        S++   S     +++    GS TT  +   +  + V+  G+ ++
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114

Query: 1423 TPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457
            T +     + +     +++  A T GS    VF++
Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 206/1019 (20%), Positives = 386/1019 (37%), Gaps = 104/1019 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T++S   F  ++   T S P+  ++  + T       P +T           V +  +  
Sbjct: 274  TTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET 333

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRP 599
            +  S++G   +     T   +GS +T   I+ S     T+ +ST   +T     EG    
Sbjct: 334  IRASTVGSETT-----TVSTTGSETTTASIMGSE----TSTDSTTGSETTTASTEGS-ET 383

Query: 600  AEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSF-----SSSGIGFGE 654
                 EGS    + + G  +  +    ++ T T        A+S+      ++S  G   
Sbjct: 384  TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443

Query: 655  SLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL-----SPRDTAKQTGIETPN--KSGKTT 707
            ++ + S  +  T   +   T     A    K      S   TA  TG+ET      G  T
Sbjct: 444  TIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDT 503

Query: 708  LSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESA 767
             +AS  G         G+         ++   +     ET    T      T T  +E +
Sbjct: 504  TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLE--TTTTSTEGS 561

Query: 768  ETMTASSSSCTVTT-GTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
            E  T S++    TT  T G G       GS   +V     ++E+    +  SE   +S  
Sbjct: 562  EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTA--DSENTTASTADSETTSASTT 619

Query: 827  ASSSSTVPVSLPSGGSLGLEKFKKPEGSW-DCELCLVQNKADSTKCLACESAKPGTKSGF 885
             S ++T   +     +   E  +    S  D E  +V          + E ++  T S  
Sbjct: 620  GSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSA- 678

Query: 886  KGFDTSSSSSNSAASSSFKFGVSS---SSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGS 942
             G +T+ S+  S  ++    G  +   S++G   T+TST         G +I  +S +GS
Sbjct: 679  TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTE--------GSEITTASITGS 730

Query: 943  --INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQF 1000
                  +EG + +    +     S+ +   E    S   + +  ++S + +  ++     
Sbjct: 731  ETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSS-ETTMASIMGSETTMA---- 785

Query: 1001 GVSNLGQEEKKEELPKSSSAGF---SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS 1057
              S +G E  K     S        +  T + ++T +   T+ T+ ++      TI   +
Sbjct: 786  --STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE------TIPAST 837

Query: 1058 ASVAPFTCKTSEAKKEEMPATKGG-FSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSL 1116
            A     T  ++E  +    +T+G   +  + E +   +A+      T    +   T+T+ 
Sbjct: 838  AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897

Query: 1117 VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQ 1176
              G +      +   + +      T  E ++ ST     T  S + SE    +T   G++
Sbjct: 898  TEGSETTTASTEGSEITTVST---TGSETTTASTEGSETTTASTEGSELTTVSTT--GSE 952

Query: 1177 TSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVS 1236
            T T + +G+     + +     S +T A++AG      ST+ S    A+ + G  +  VS
Sbjct: 953  TITVSAEGSETTTVTTMG----SETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVS 1007

Query: 1237 SSAFGNTAESST-SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATT 1295
            S+    T  S+T +++ + S +    TT +T  + T  V+  G+ +  T+T G     TT
Sbjct: 1008 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG---SETT 1064

Query: 1296 TSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGS 1355
            T S+ GS             + A  A+   T   + G+        GS   +T ++ TGS
Sbjct: 1065 TVSTTGSE-----------TTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGS 1111

Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415
            +       T ++S++        S++   S T+  +++A   GS  T    T +  + V 
Sbjct: 1112 K-------TTTASTEG-------SEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVS 1157

Query: 1416 TFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSG----TSFSGRKIKTA 1470
            T G+ ++T +A+   + +     +++  A T GS      ++       S SG +  TA
Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTA 1216



 Score = 85.9 bits (211), Expect = 3e-16
 Identities = 186/973 (19%), Positives = 359/973 (36%), Gaps = 75/973 (7%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANV 539
            T S   T +    E +T S +   ++ A T   + T+ S+ GS     S+   ++T  ++
Sbjct: 349  TGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSI 408

Query: 540  LPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598
                +     +    + +E++  S+T+ E   +S+     T+ ST+  +T     EG   
Sbjct: 409  TDSET-----TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS-E 462

Query: 599  PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKA 658
               +   GS      + G  +    +   + T     V+T   I S +++    G    A
Sbjct: 463  TTTVTTAGSETKTAYTTGSETTTASNTGLETTT----VFT---IGSDTTTASTEGSETTA 515

Query: 659  GSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKS--GKTTLSASGTGFG 716
             S+   +   +  + ++N  ++   ++ +   T   TG+ET   S  G    + S TG  
Sbjct: 516  VSATGSEMTTVSTEGSENTTVSTTGSETT---TVSTTGLETTTTSTEGSEMTTVSTTGAE 572

Query: 717  DKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSS 776
                   G+         ++   +     E     T      T +  +  +ET TAS++S
Sbjct: 573  TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE--TTSASTTGSETTTASTTS 630

Query: 777  CTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVS 836
               TT +           GS   +V   + ++E     +  SE+  +S   S ++TV  +
Sbjct: 631  SETTTASTE---------GSETTTVS--TTDSETTMVSTTGSERTITSTEGSETTTVSAT 679

Query: 837  LPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSN 896
                   G E     EGS    + +  ++         E+    T+       + + S  
Sbjct: 680  -------GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSET 732

Query: 897  SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956
            + AS+      ++S+ G   T  ST     G +       SS++   + M      +  I
Sbjct: 733  TTASTEGSETTTASTEGSETTSASTT----GSETTTASTTSSETTMASIMGSETTMASTI 788

Query: 957  GDFKFGVSS-ESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELP 1015
            G     VS+  SK   V  ++         +S  +   +        S  G E       
Sbjct: 789  GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTT--- 845

Query: 1016 KSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEM 1075
             +S+ G    T     +     +  +SE  ++  +G+  T +++    T  TS    E  
Sbjct: 846  -TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 1076 PATKGGFSFGNVEPASLPSASVFVLGR------TEEKQQEPVTST-SLVFGKKADNEEPK 1128
             A+  G     V      + +    G       TE  +   V++T S      A+  E  
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 1129 CQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATF--AFGAQTSTTADQGAA 1186
               V + G+   T     S++T   +    +   S + ++ T   + G++T+T +  G  
Sbjct: 965  T--VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTE 1022

Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAES 1246
              + S    +  S +T  T+AG       T+ S     +    +++   ++ +   TA +
Sbjct: 1023 TTITS----TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078

Query: 1247 STSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSG-------FGFGATTTSSS 1299
            +  ++   S      TT+ST  + T  V+  G+ +   +T G            TTT+S+
Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAST 1138

Query: 1300 AGSSF--VFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTA--LFPTGS 1355
             GS    VF T     + S   G+  T +      A+  +  G  + ++STA     T S
Sbjct: 1139 TGSEMTTVFTTVSETTTVS-TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAS 1197

Query: 1356 QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVF 1415
                 T    +S S+        S+++  S     +++AF  GS TT  +  +  P+   
Sbjct: 1198 TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATS 1257

Query: 1416 TFGANSSTPAASA 1428
              G+ ++T + +A
Sbjct: 1258 LTGSETTTVSITA 1270



 Score = 84.3 bits (207), Expect = 8e-16
 Identities = 157/800 (19%), Positives = 285/800 (35%), Gaps = 65/800 (8%)

Query: 691  TAKQTGIETP-NKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749
            TA   G ET  + +G  T + S TG        +G+         ++         ET  
Sbjct: 87   TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146

Query: 750  PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809
              T      T T  +  +ET  AS++   +TT      +         E +   VS    
Sbjct: 147  VSTVGSE--TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTT--VSTAGS 202

Query: 810  DNKCVSCMSEKPGSSVPASSSSTVPVSLPSG----GSLGLEKFKKPEGSWDCELCLVQNK 865
            +   VS    +  ++  A S +T   ++ S      + G E      GS   E      +
Sbjct: 203  ETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---ETTAASTE 259

Query: 866  ADSTKCLACESAKPGTKSGFKGFDTSSSSSNSA----ASSSFKFGVSSSSSGPSQTLTST 921
               T     E +K  T S   GF+T+++S+  +    AS+       +S+ GP  T  ST
Sbjct: 260  DSETNTAFTEDSKTTTAST-TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVST 318

Query: 922  GN------FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKD 975
             +      F  G +      V S++ +++        +  +G      S+          
Sbjct: 319  ASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTAST 378

Query: 976  SKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAP 1035
              ++          +  VS T  +    ++   E      + S       T    +T + 
Sbjct: 379  EGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAST 438

Query: 1036 ANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSA 1095
              + +T  + S     T  T+ +     T   SE K     A   G          L + 
Sbjct: 439  EGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT----AYTTGSETTTASNTGLETT 494

Query: 1096 SVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTK-----DENSSKST 1150
            +VF +G          + T+ V    ++          S   SE T       E ++ ST
Sbjct: 495  TVFTIGSDTTTASTEGSETTAVSATGSE------MTTVSTEGSENTTVSTTGSETTTVST 548

Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210
                 T  S + SE    +T   GA+T+T + +G              S +T A++AG  
Sbjct: 549  TGLETTTTSTEGSEMTTVSTT--GAETTTDSTEG--------------SGTTAASTAGSE 592

Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV 1270
                ST+ S    A+    ++++  ++ +   TA +++S++   S +    TT ST  + 
Sbjct: 593  TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652

Query: 1271 TPFVFGPGA--------SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGAN 1322
            T  V   G+         S  TT S  G   T ++  +G++ V  TG      S   G+ 
Sbjct: 653  TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-GSE 711

Query: 1323 QTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ 1380
             T T  +    +  +  G  + ++ST  +   T S     T    ++ S+        S+
Sbjct: 712  TTITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE 771

Query: 1381 SAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQ 1440
            +   S     ++ A   GS TT  +  ++  + VFT  + ++  + +A  + +     ++
Sbjct: 772  TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 1441 SPAAFTVGSNGKNVFSSSGT 1460
            +  A T GS      S+ G+
Sbjct: 832  TIPASTAGSETTTTTSTEGS 851



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 193/1045 (18%), Positives = 371/1045 (35%), Gaps = 94/1045 (8%)

Query: 478  PITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEA 537
            P   S+  T + +  E TT       ++ A T   + T+PS TGS     S    + T  
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT 68

Query: 538  NVLPPSSIGFTFSVPVAKTAELSGSSSTL---------------EPIISSSAHHVTTVNS 582
            +     +   + +     TA ++GS +T+               E  + S+    TT NS
Sbjct: 69   STAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS 128

Query: 583  TNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAI 642
            T   +T      G         E + +  + S    +   DS     + T   + T    
Sbjct: 129  TTSSETTVTSTAG--------SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 643  SSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNK 702
             S + +    G      S+   +T  +    ++    +   ++ +   T      +    
Sbjct: 181  GSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA 240

Query: 703  SGKTTLSASGTGFGDKFKPVIGTWDCDTCLV---QNKPEAIKCVACETPKPGTC-VKRAL 758
              +TT+S +G+           T D +T       +K         ET    T   +  +
Sbjct: 241  GSETTVSTAGSE-----TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295

Query: 759  TLTVVSESA-------ETMTASSSSCTVTTGTLGFGDKFK-RPIGSWECSVCCVSNNAED 810
              T+ SE+        ET   S++S  VTT      +  +   +GS       VS    +
Sbjct: 296  ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS---ETTTVSTTGSE 352

Query: 811  NKCVSCM-SEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869
                S M SE    S   S ++T         +   E  +    S         +  DS 
Sbjct: 353  TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412

Query: 870  KCLACESAKPGTKSGFKGFDTSSSSSNS-----AASSSFKFGVSSSSSGPSQTLTSTGN- 923
                C      T      F+T+++S+       A++S  +   +S+    + T+T+ G+ 
Sbjct: 413  TTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSE 472

Query: 924  FKFGDQGGFKIGVSSDSG----SINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKND 979
             K     G +   +S++G    ++  +      +   G     VS+            ++
Sbjct: 473  TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532

Query: 980  NFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTI 1039
            N     +   +  VS T    G+       +  E+   S+ G    T   +ST     T 
Sbjct: 533  NTTVSTTGSETTTVSTT----GLETTTTSTEGSEMTTVSTTGAETTT---DSTEGSGTTA 585

Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099
             ++    +  + T ++++ + +    +T+ A       T    +      AS   +    
Sbjct: 586  ASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT 645

Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFS---MT 1156
            +  T+   +  + ST+         E  +   V + G+      E S  +T S +    T
Sbjct: 646  VSTTD--SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETT 703

Query: 1157 KPSEKESEQPAKAT--------FAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG 1208
            K S   SE    +T           G++T+T + +G+     S    +  S +T A++ G
Sbjct: 704  KVSTTGSETTITSTEGSEITTASITGSETTTASTEGSETTTAS----TEGSETTSASTTG 759

Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSS 1265
                 +ST+SS   +A+ +   S   ++S+    T + ST+ S    +F+++S+    S+
Sbjct: 760  SETTTASTTSSETTMASIM--GSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817

Query: 1266 T-------GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGS-SFVFGTGPSAPSASP 1317
            T        TA +  +    A S  TTT+      TTT+S+ GS +    T  S  + + 
Sbjct: 818  TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877

Query: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSST--ALFPTGSQPAPPTFGTVSSSSQPPVFG 1375
              G+  T    +    +  +  G  + ++ST  +   T S     T    +  S+     
Sbjct: 878  TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937

Query: 1376 QQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGG 1435
             + S+    S T   + +    GS TT      +  +   T G+ ++T + +   + +  
Sbjct: 938  TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTAS 997

Query: 1436 FPFNQSPAAFTVGSNGKNVFSSSGT 1460
               +++    + GS    V S++GT
Sbjct: 998  IEGSETTTVSSTGSETTTV-STTGT 1021



 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 186/934 (19%), Positives = 323/934 (34%), Gaps = 98/934 (10%)

Query: 480  TSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTE--- 536
            T S + T +    E TT S +   ++   T  ++ T+ S+ GS M   S+   ++T    
Sbjct: 519  TGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDST 578

Query: 537  --ANVLPPSSIGF-TFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDC 593
              +     S+ G  T +V  A +   + S++  E   +S+    TT  ST   +T     
Sbjct: 579  EGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAST 638

Query: 594  EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFG 653
            EG      +    S   ++ + G +   I S     T T     +   +S+  S      
Sbjct: 639  EGS-ETTTVSTTDSETTMVSTTG-SERTITSTEGSETTTVSATGSETTVSTEGSGTTTV- 695

Query: 654  ESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKL--SPRDTAKQTGIETPNKS--GKTTLS 709
             S+    + +  T   +  +T  +      A +  S   TA   G ET   S  G  T S
Sbjct: 696  -SITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTS 754

Query: 710  ASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAET 769
            AS TG          +      ++ ++      +  ET K  T   +  T  V +E++ET
Sbjct: 755  ASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT--VFTENSET 812

Query: 770  MTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASS 829
              AS+++   TT +    +         E +    +  +E     +  SE   +S  +S 
Sbjct: 813  TIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSE 872

Query: 830  SSTVPVSLPSGGSLGLEKFK-KPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGF 888
            ++T         ++G E      EGS   E      +   T   + E ++  T S     
Sbjct: 873  TTTAT-------TIGSETTTASTEGS---ETTTTSTEGSETTTASTEGSEITTVS----- 917

Query: 889  DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS---SDSGSINP 945
              ++ S  + AS+      ++S+ G   T  ST        G   I VS   S++ ++  
Sbjct: 918  --TTGSETTTASTEGSETTTASTEGSELTTVST-------TGSETITVSAEGSETTTVTT 968

Query: 946  MSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNL 1005
            M      +   G     VS+            ++      +   +  VS T  +  +++ 
Sbjct: 969  MGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITST 1028

Query: 1006 GQEEKKEELPKSSSAGFSFGTG---VINSTPAPANTIVTSENKSSFNLGTIETKSASVAP 1062
               E        S     + TG      ST     T V++    +    T + ++ +V+ 
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVST 1088

Query: 1063 FTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS---LVFG 1119
                T+ A       T    +      AS   +    +  T  +     T+ S    VF 
Sbjct: 1089 SGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFT 1148

Query: 1120 KKADNEEPKC----QPVFSFGNSEQTK-----DENSSKSTFSFSMTKPSEKESEQPAKAT 1170
              ++              S   SE T       E ++ ST     T  S   SE    +T
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208

Query: 1171 FAF--------GAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPP 1222
                       G++TST +  G+       + + ++ +ST               +S  P
Sbjct: 1209 SGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAST---------------ASLEP 1253

Query: 1223 VATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSN 1282
             AT + G  +  VS +A G TA S+T  S  F        T +T  ++ P    P + + 
Sbjct: 1254 TATSLTGSETTTVSITASGATAASTTVSSTTF------VLTKATDVSIQPITNTPMSGTR 1307

Query: 1283 NTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFG 1342
             T     G   T +SS   +  +  T  +A    P    N +     + GAS        
Sbjct: 1308 TT-----GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGV 1362

Query: 1343 SISSSTALFPTGS---QPAPPTFG--TVSSSSQP 1371
              ++ +   PT S   +  P + G  TVS S  P
Sbjct: 1363 RTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTP 1396



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 166/869 (19%), Positives = 303/869 (34%), Gaps = 104/869 (11%)

Query: 476  SLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKST 535
            S   T S   T + +S E TT+S     ++   T   + T  S+TGS     S+   ++T
Sbjct: 615  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 536  -------EANVLPPSSIGFTFSVPVAKTAELS--GSSSTLEPIISSSAHHVTTVNSTNCK 586
                   E  V    S   T S+  ++T ++S  GS +T   I S+    +TT + T   
Sbjct: 675  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETT---ITSTEGSEITTASITG-S 730

Query: 587  KTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFS 646
            +T     EG         EGS      + G      ++  A  T++   + +     +  
Sbjct: 731  ETTTASTEGS-ETTTASTEGSETTSASTTG-----SETTTASTTSSETTMASIMGSETTM 784

Query: 647  SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706
            +S IG   +  + +S +  T   +N  ++    +  A++ +   TA    I       +T
Sbjct: 785  ASTIGSETTKVSTASSKMTTVFTEN--SETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 707  TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766
            T + S  G         G+         ++      +  ET    T  + + T T  +E 
Sbjct: 843  TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST--EGSETTTTSTEG 900

Query: 767  AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
            +ET TAS+    +TT            + +        S    +    S    +  ++V 
Sbjct: 901  SETTTASTEGSEITT------------VSTTGSETTTASTEGSETTTASTEGSEL-TTVS 947

Query: 827  ASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFK 886
             + S T+ VS               EGS    +  + ++  +      E+    T     
Sbjct: 948  TTGSETITVS--------------AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 887  GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946
               +   S  +  SS+     + S++G   T+TST     G +        S++ ++   
Sbjct: 994  TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTE----GSETTTVTTAGSETTAV--- 1046

Query: 947  SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLG 1006
                          +   SE+     +          G  +  ++   L       S  G
Sbjct: 1047 --------------YTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 1007 QEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCK 1066
                     ++++    + TG   +T +   +  T+ + +S    T  T  + +      
Sbjct: 1093 TTTASTAGSETTTV---YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149

Query: 1067 TSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEE 1126
             SE        T    + G+    S  + S      TE  +    T+T+   G +     
Sbjct: 1150 VSE--------TTTVSTIGSEATTSSAAGSEATTTSTEGSE----TTTASTAGSETTTAS 1197

Query: 1127 PKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAA 1186
                   +   S     E ++  T     + PS   SE      F  G++T T A   + 
Sbjct: 1198 TAGSETTTASTS---GSETNTACTTGSETSTPSSAGSE--TNTAFIIGSET-TIASTASL 1251

Query: 1187 KPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAF------ 1240
            +P  + L  + S ++T + +A G    S+T SS   V T     S  P++++        
Sbjct: 1252 EPTATSL--TGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1309

Query: 1241 GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS--NNTTTSGFGFGATTTSS 1298
            G    +S+S ++    D   +  S T   +     G G S+   ++TTS  G   TT S+
Sbjct: 1310 GTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369

Query: 1299 SAGSSFVF-GTGPSAPSASPAFGANQTPT 1326
               +S  F  TGP +   +     + TPT
Sbjct: 1370 REPTSSTFQETGPVSMGTN-TVSMSHTPT 1397



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 50/197 (25%), Positives = 80/197 (40%), Gaps = 29/197 (14%)

Query: 1277 PGASSNNTTTSGFGF---------GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTF 1327
            P A SN TT S  G            TTT+S+AGS     T PS   +     +      
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET---TTPSPTGSQTTIVSISGSEI 65

Query: 1328 GQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQ-SAFGSG 1386
              +  A   N     + S +T     GS+    T G  S ++   + G + +  SA GS 
Sbjct: 66   TTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAG--SETTTVSITGTETTMVSAMGSE 123

Query: 1387 TTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446
            TT NS+++    S TT  +   +  + V T G+ ++T   +           +++ AA T
Sbjct: 124  TTTNSTTS----SETTVTSTAGSETTTVSTVGSETTTAYTAD----------SETTAAST 169

Query: 1447 VGSNGKNVFSSSGTSFS 1463
             GS    VF++   + +
Sbjct: 170  TGSEMTTVFTAGSETIT 186


>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
            sapiens]
          Length = 834

 Score = 91.7 bits (226), Expect = 5e-18
 Identities = 145/585 (24%), Positives = 213/585 (36%), Gaps = 128/585 (21%)

Query: 823  SSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKP--- 879
            SS+P ++S+T P   P   S+G      P  S    L     K  +T   A  +  P   
Sbjct: 342  SSLPTTTSTTAPTFQPVFSSMG------PPAS--VPLPAPFFKQTTTPATAPTTTAPLFT 393

Query: 880  ---GTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGN-----FKFGDQGG 931
                  S      ++S S++SA+  +F FG++S SS    T TST       F FG    
Sbjct: 394  GLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG---- 449

Query: 932  FKIGVSSDSGSINPMSEGFKFSKPIGD-FKFGVSSESKPEEVKKDSKNDNFKFGLSSGLS 990
                         P +    F+  +G  F+FG     KP  +   +    F   L + + 
Sbjct: 450  ------------APQASAASFTPAMGSIFQFG-----KPPALPTTTTVTTFSQSLPTAVP 492

Query: 991  NPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFS-FGTGVINSTPAPANTIVTSENKSSFN 1049
               S                      SS+A FS FG+ +  S PA ++    + + +S  
Sbjct: 493  TATS----------------------SSAADFSGFGSTLATSAPATSSQPTLTFSNTSTP 530

Query: 1050 LGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPS-ASVFVLGRTEEKQQ 1108
               I   S++ +P         +    A +G    G  +PA  PS  S F  G +     
Sbjct: 531  TFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQ-PPGAAKPALTPSFGSSFTFGNSAAPAA 589

Query: 1109 EPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAK 1168
             P  +   +      +     QP F            ++ S F    T            
Sbjct: 590  APTPAPPSMIKIVPAHVPTPIQPTFG----------GATHSAFGLKAT------------ 627

Query: 1169 ATFAFGAQTSTTADQGAAKPVFSFLNNSSS----SSSTPATSAGGGIFGSSTSSSNPPVA 1224
               AFGA  S+    G +  VFSF   +SS    ++ T ++ +   +FGS+T S      
Sbjct: 628  -ASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPS------ 680

Query: 1225 TFVFGQSSNPVSSSAFG-NTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNN 1283
             F FG S+ P  S +FG N A   +S           ATT +       F FG G S + 
Sbjct: 681  PFTFGGSAAPAGSGSFGINVATPGSS-----------ATTGA-------FSFGAGQSGST 722

Query: 1284 TTTSGF--GFGATTTSSSAGSS-FVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPG 1340
             T++ F  G G     ++  S+ F F  G S   + P FG   TPTFG +  A     PG
Sbjct: 723  ATSTPFAGGLGQNALGTTGQSTPFAFNVG-STTESKPVFGGTATPTFGLNTPA-----PG 776

Query: 1341 FGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGS 1385
             G+ S S+  F   S PA    G     S  P F         G+
Sbjct: 777  VGT-SGSSLSFGASSAPAQGFVGVAPFGSAAPSFSIGAGSKTLGA 820



 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 141/513 (27%), Positives = 197/513 (38%), Gaps = 139/513 (27%)

Query: 1031 STPAPANTIVTSENKSSFNLGTIETKSAS-VAPFTCKTSEAKKEEMPATKGGFSFGNVEP 1089
            S P+PA        K SF  GT  T  +S  AP     S   K    A       G   P
Sbjct: 278  SAPSPAP-------KQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPP 330

Query: 1090 ASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKS 1149
               PS S      T        T+TS           P  QPVFS           S   
Sbjct: 331  G--PSVSA-----TAPSSSSLPTTTSTT--------APTFQPVFS-----------SMGP 364

Query: 1150 TFSFSMTKPSEKESEQPA--------------KATFAFGAQTSTT-ADQGAAKPVFSFLN 1194
              S  +  P  K++  PA               AT A    TS + +   A+KP F F  
Sbjct: 365  PASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGI 424

Query: 1195 NSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLF 1254
            NS SSSS   T++      ++T++S P    F+FG    P +S+A    A  S  Q   F
Sbjct: 425  NSVSSSSVSTTTS------TATAASQP----FLFGA---PQASAASFTPAMGSIFQ---F 468

Query: 1255 SQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSS----------- 1303
             +   L TT++  T           +++++     GFG+T  +S+  +S           
Sbjct: 469  GKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTS 528

Query: 1304 ---FVFGTGPSAPSASPAF-GANQTPTFG----QSQGASQPN-PPGFGSI-----SSSTA 1349
               F    G SA S  P++ GAN  P FG    Q  GA++P   P FGS      S++ A
Sbjct: 529  TPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPA 588

Query: 1350 LFPTGSQPA-------------PPTFGTVSSS---------------SQPPVFGQQPSQS 1381
              PT + P+              PTFG  + S               S  P FG   +  
Sbjct: 589  AAPTPAPPSMIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVF 648

Query: 1382 AFGSGTTPNSSSAFQF---GSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPF 1438
            +FG+ T+    +  Q    GSS++ F  T  SP   FTFG        SA P+GSG F  
Sbjct: 649  SFGAATSSGFGATTQTASSGSSSSVFGSTTPSP---FTFG-------GSAAPAGSGSFGI 698

Query: 1439 N-------QSPAAFTVGSNGKNVFSSSGTSFSG 1464
            N        +  AF+ G+ G++  +++ T F+G
Sbjct: 699  NVATPGSSATTGAFSFGA-GQSGSTATSTPFAG 730



 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 142/535 (26%), Positives = 196/535 (36%), Gaps = 107/535 (20%)

Query: 991  NPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFS-FGTGVINST---PAPANTIVTSENKS 1046
            +P     F FG  N            S+S  F    T    S    P P    V++   S
Sbjct: 281  SPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVSATAPS 340

Query: 1047 SFNLGTIETKSA-SVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPS--ASVFVLGRT 1103
            S +L T  + +A +  P            +PA    F      PA+ P+  A +F    +
Sbjct: 341  SSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAP---FFKQTTTPATAPTTTAPLFTGLAS 397

Query: 1104 EEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKES 1163
                  P+TS S        + +   +P F FG +        S S+ S S T  +   +
Sbjct: 398  ATSAVAPITSAS-------PSTDSASKPAFGFGIN--------SVSSSSVSTTTSTATAA 442

Query: 1164 EQPAKATFAFGA-QTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPP 1222
             QP    F FGA Q S  +   A   +F F    +  ++T  T+       S +  +  P
Sbjct: 443  SQP----FLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTF------SQSLPTAVP 492

Query: 1223 VATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSN 1282
             AT     SS+    S FG+T   +TS     SQ +   + +ST T   PF    G+S+ 
Sbjct: 493  TAT-----SSSAADFSGFGSTL--ATSAPATSSQPTLTFSNTSTPTFNIPF----GSSAK 541

Query: 1283 NTTTSGFG------FGAT----------TTSSSAGSSFVFGTG--------PSAPSA--- 1315
            +   S  G      FGA             + S GSSF FG          P+ PS    
Sbjct: 542  SPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAAAPTPAPPSMIKI 601

Query: 1316 ---------SPAFGANQTPTFG-----QSQGASQPNPPGFGSISSSTALFPTGSQPAP-- 1359
                      P FG      FG      + GA   + P FG    STA+F  G+  +   
Sbjct: 602  VPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGG---STAVFSFGAATSSGF 658

Query: 1360 -PTFGTVSSSSQPPVFGQQ-PSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTF 1417
              T  T SS S   VFG   PS   FG    P  S +F    +T   + T    +G F+F
Sbjct: 659  GATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSAT----TGAFSF 714

Query: 1418 GANSSTPAASAQPSGSG------GFPFNQSPAAFTVGS--NGKNVFSSSGTSFSG 1464
            GA  S   A++ P   G      G     +P AF VGS    K VF  + T   G
Sbjct: 715  GAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFG 769



 Score = 70.9 bits (172), Expect = 9e-12
 Identities = 113/474 (23%), Positives = 178/474 (37%), Gaps = 78/474 (16%)

Query: 1033 PAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASL 1092
            PAP     T+   +      + T  AS        + A      A+K  F FG     S+
Sbjct: 371  PAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGI---NSV 427

Query: 1093 PSASVFVLGRTEEKQQEPVTSTSLVFGK---KADNEEPKCQPVFSFGNSEQTKDENSSKS 1149
             S+SV     T     +P      +FG     A +  P    +F FG         ++ +
Sbjct: 428  SSSSVSTTTSTATAASQP-----FLFGAPQASAASFTPAMGSIFQFGKPPALPT-TTTVT 481

Query: 1150 TFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGG 1209
            TFS S+       +   A     FG+  +T+A   +++P  +F N S+ + + P  S+  
Sbjct: 482  TFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAK 541

Query: 1210 GIFGSSTSSSNPPVATFVFGQ---SSNPV------SSSAFGNTAESSTSQSLLFSQDSKL 1260
                S   ++  P      GQ   ++ P       SS  FGN+A  + + +       K+
Sbjct: 542  SPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAAAPTPAPPSMIKI 601

Query: 1261 ATTSSTGTAVTPFVFGP--GASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPA 1318
               +   T + P   G    A     T S FG  A++  +  GS+ VF  G +  S    
Sbjct: 602  VP-AHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSG--- 657

Query: 1319 FGAN-QTPTFGQSQ---GASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVF 1374
            FGA  QT + G S    G++ P+P  FG  ++     P GS        T  SS+    F
Sbjct: 658  FGATTQTASSGSSSSVFGSTTPSPFTFGGSAA-----PAGSGSFGINVATPGSSATTGAF 712

Query: 1375 GQQPSQSAFGSGT--------------------TPNSSSAFQF-------------GSST 1401
                   +FG+G                     T   S+ F F             G++T
Sbjct: 713  -------SFGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTAT 765

Query: 1402 TNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGF-PFNQSPAAFTVGSNGKNV 1454
              F     +P GV T G++ S  A+SA   G  G  PF  +  +F++G+  K +
Sbjct: 766  PTFGLNTPAP-GVGTSGSSLSFGASSAPAQGFVGVAPFGSAAPSFSIGAGSKTL 818



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 134/595 (22%), Positives = 209/595 (35%), Gaps = 96/595 (16%)

Query: 496  TSSPSPINSSQALTNKVQMTSPSS-------TGSPMFK--FSSPIVKSTEANVLPPSSIG 546
            TS+PSP    Q+     Q TSPSS       + SPMFK  F++P     E    P  S+ 
Sbjct: 277  TSAPSPA-PKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVS 335

Query: 547  FTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPAEILKEG 606
             T     +     S ++ T +P+ SS                PP        PA   K+ 
Sbjct: 336  ATAPSSSSLPTTTSTTAPTFQPVFSSMG--------------PPASVP---LPAPFFKQT 378

Query: 607  SVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDT 666
            +      +P   +P    +A+  +A +P+    P+  S S    GFG +  + SS    T
Sbjct: 379  TTP--ATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTT 436

Query: 667  CLLQNKVTDNKCIACQAAKLSPRDTAKQTGI-ETPNKSGKTTLSASGTGFGDKFKPVIGT 725
                                S    A Q  +   P  S  +   A G+ F     P + T
Sbjct: 437  --------------------STATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPT 476

Query: 726  WDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLG 785
                T   Q+ P A+      +    +     L  +  + S++  T + S+ +  T  + 
Sbjct: 477  TTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQP-TLTFSNTSTPTFNIP 535

Query: 786  FGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASS----------SSTVPV 835
            FG   K P+ S+  +    +  A +        + PG++ PA +          +S  P 
Sbjct: 536  FGSSAKSPLPSYPGANPQPAFGAAE-------GQPPGAAKPALTPSFGSSFTFGNSAAPA 588

Query: 836  SLPSGGSLGLEKFKKPEGSWDCELCL--VQNKADSTKCLACESAKPGTKSGFKGFDTSSS 893
            + P+     + K          +       + A   K  A     P +     G  T+  
Sbjct: 589  AAPTPAPPSMIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVF 648

Query: 894  SSNSAASSSFKFGVSSSSSGPSQTL---TSTGNFKFGDQGGFKIGVSSDSGSINPMSEGF 950
            S  +A SS F     ++SSG S ++   T+   F F   GG      S S  IN  + G 
Sbjct: 649  SFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTF---GGSAAPAGSGSFGINVATPG- 704

Query: 951  KFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGL-SSGLSNPVSLTPFQFGVSNLGQEE 1009
              S   G F FG             + +  F  GL  + L      TPF F V +    E
Sbjct: 705  -SSATTGAFSFGAGQSG------STATSTPFAGGLGQNALGTTGQSTPFAFNVGS--TTE 755

Query: 1010 KKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS-ASVAPF 1063
             K     +++  F        +TPAP   + TS +  SF   +   +    VAPF
Sbjct: 756  SKPVFGGTATPTFGL------NTPAPG--VGTSGSSLSFGASSAPAQGFVGVAPF 802



 Score = 50.8 bits (120), Expect = 9e-06
 Identities = 88/358 (24%), Positives = 137/358 (38%), Gaps = 71/358 (19%)

Query: 1140 QTKDENSSKSTFSFSMTKPSEKES---EQPAKATFAFGAQTSTTADQGAAKPVFSFLNNS 1196
            Q  ++ S  ++ S + T P  + S     PA A     A   T+    +  P+   L   
Sbjct: 133  QALEDKSDAASNSVTETPPITQPSFTFTLPAAAP----ASPPTSLLAPSTNPLLESLKKM 188

Query: 1197 SSSSSTPATSAGGGIFGSSTSSSNPP-----VATFVFGQSSNP--VSSSAFGNTAESST- 1248
             +  S P      G   ++T + +PP     +      QS  P  + S +F +   ++  
Sbjct: 189  QTPPSLPPCPESAG--AATTEALSPPKTPNLLPPLGLSQSGPPGLLPSPSFDSNPPTTLL 246

Query: 1249 ----SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSF 1304
                + S++ + D+K   T    T   P      ++ +      F FG   TS S+ ++ 
Sbjct: 247  GLIPAPSMVPATDTKAPPTLQAETTTKPQAT---SAPSPAPKQSFLFGTQNTSPSSPAA- 302

Query: 1305 VFGTGPSAPSASPAFGANQT-PTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFG 1363
                 P+A SASP F    T P   + +G + P P    +  SS++L PT +    PTF 
Sbjct: 303  -----PAASSASPMFKPIFTAPPKSEKEGPTPPGPSVSATAPSSSSL-PTTTSTTAPTFQ 356

Query: 1364 TVSSSSQPPV-------FGQQPSQSAFGSGTT---------------------PNSSS-- 1393
             V SS  PP        F +Q +  A    TT                     P++ S  
Sbjct: 357  PVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSAS 416

Query: 1394 --AFQFG------SSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPA 1443
              AF FG      SS +    T  + S  F FGA  ++ AAS  P+    F F + PA
Sbjct: 417  KPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQAS-AASFTPAMGSIFQFGKPPA 473


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 107/441 (24%), Positives = 181/441 (41%), Gaps = 42/441 (9%)

Query: 1018 SSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPA 1077
            +S   + G+ VI+S  + A    +S   S  +  TI   S +    +  T+     E   
Sbjct: 27   TSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNS----EFHT 82

Query: 1078 TKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGN 1137
            T  G S       S  S+ + +   +E       TS+       +++  P      +  +
Sbjct: 83   TSSGISTATNSEFSTVSSGISIATNSESS----TTSSGASTATNSESSTPSSGASTATNS 138

Query: 1138 SEQTKDENSSKSTFSFSMTKPSEKESEQPAKA-TFAFGAQTSTTADQGAAKPVFSFLNNS 1196
               T    +S +T S S T  SE  +   +++ T + GA T+T ++        S   NS
Sbjct: 139  DSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNS 198

Query: 1197 SSS-----------SSTPATSAGGGIFGSSTSSSNPPVA-TFVFGQSSNPVSSSAFGNTA 1244
             SS           S +  TS G G   +S SS+    A T    +SS P S +     +
Sbjct: 199  ESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNS 258

Query: 1245 ESSTSQSLLFSQDSKLATTSSTGTAV-------TPFVFGPGASSNNTTTSGFGFGATTTS 1297
            ESST+ S   +  +  ++T S+G +        TP      A+++ ++T+  G    T S
Sbjct: 259  ESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNS 318

Query: 1298 SSAGSSFVFGTGPSAPSASPAFGAN---QTPTFGQSQGASQPNPPGFGSISSSTALFPTG 1354
             S+ +S    T  ++ S++ + GA+    + +   S GAS     G  + SS T+   T 
Sbjct: 319  DSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTST-ATN 377

Query: 1355 SQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGV 1414
            S+ +     TVSS +      +  + S+  S  T + SS    G+ST       NS S  
Sbjct: 378  SESS-----TVSSGASTATTSESSTTSSGASTATNSESSTVSSGAST-----ATNSESST 427

Query: 1415 FTFGANSSTPAASAQPSGSGG 1435
             + GAN++T + S+  S   G
Sbjct: 428  TSSGANTATNSGSSVTSAGSG 448



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 109/449 (24%), Positives = 187/449 (41%), Gaps = 59/449 (13%)

Query: 986  SSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENK 1045
            SSG+S   + T  +F   + G          ++S+G S  T   +STP+   +  T+ + 
Sbjct: 84   SSGIS---TATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDS 140

Query: 1046 SSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEE 1105
            S+ + G     ++  +  + + S A   E   T  G S      +S  S+       +E 
Sbjct: 141  STTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSES 200

Query: 1106 KQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQ 1165
                   ST       A N E +     S G    T   NS  ST S   +  +  ES  
Sbjct: 201  STTSSGAST-------ATNSESRTT---SNGAGTAT---NSESSTTSSGASTATNSESST 247

Query: 1166 PAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSS-NPPVA 1224
            P+      GA T+T               NS SS+    TS+G G   +S SS+ +  ++
Sbjct: 248  PSS-----GAGTAT---------------NSESST----TSSGAGTATNSESSTVSSGIS 283

Query: 1225 TFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNT 1284
            T    +SS P S +     +ESST+ S   +  +  ++T+S+G +         A+++ +
Sbjct: 284  TVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGAST--------ATNSES 335

Query: 1285 TTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSI 1344
            +T+  G    T S S+ +S    T  ++ S++ + G + T T  +S   S        S 
Sbjct: 336  STTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTS-TATNSESSTVSSGASTATTSE 394

Query: 1345 SSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNF 1404
            SS+T+   +G+  A  +  +  SS        + S ++ G+ T  NS      GSS T+ 
Sbjct: 395  SSTTS---SGASTATNSESSTVSSGASTATNSESSTTSSGANTATNS------GSSVTSA 445

Query: 1405 NFTNNSPSGVFTFGANSSTPAASAQPSGS 1433
                 + +G+ T   ++ST  + A+P GS
Sbjct: 446  GSGTAALTGMHTTSHSASTAVSEAKPGGS 474



 Score = 81.6 bits (200), Expect = 5e-15
 Identities = 102/428 (23%), Positives = 177/428 (41%), Gaps = 59/428 (13%)

Query: 1041 TSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVL 1100
            ++E  +S N G+    S +        S A       T  G S   +  +S+ S  V ++
Sbjct: 24   SNETSTSANTGSSVISSGA--------STATNSGSSVTSSGVSTATISGSSVTSNGVSIV 75

Query: 1101 GRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSE 1160
              +E        ST       A N E      FS  +S  +   NS  ST S   +  + 
Sbjct: 76   TNSEFHTTSSGIST-------ATNSE------FSTVSSGISIATNSESSTTSSGASTATN 122

Query: 1161 KESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSN 1220
             ES  P+      GA T+T +D           ++++SS ++ AT++      SST+SS 
Sbjct: 123  SESSTPSS-----GASTATNSD-----------SSTTSSGASTATNSD-----SSTTSSE 161

Query: 1221 PPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGAS 1280
               AT    +SS   S ++    +ESST  S   +  +  ++T+S+G +         A+
Sbjct: 162  ASTATN--SESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGAST--------AT 211

Query: 1281 SNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGA-----NQTPTFGQSQGASQ 1335
            ++ + T+  G G  T S S+ +S    T  ++ S++P+ GA     +++ T     G + 
Sbjct: 212  NSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTAT 271

Query: 1336 PNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAF 1395
             +     S   ST      S P+       +S S     G   + ++  S T+  +S+A 
Sbjct: 272  NSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTAT 331

Query: 1396 QFGSSTTN--FNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKN 1453
               SSTT+   +   NS S   + GA+++T + S+  S       N   +  + G++   
Sbjct: 332  NSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTAT 391

Query: 1454 VFSSSGTS 1461
               SS TS
Sbjct: 392  TSESSTTS 399



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 113/462 (24%), Positives = 184/462 (39%), Gaps = 60/462 (12%)

Query: 889  DTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE 948
            +T SS  +S AS++   G S +SSG S T T +G+            V+S+  SI   SE
Sbjct: 32   NTGSSVISSGASTATNSGSSVTSSGVS-TATISGS-----------SVTSNGVSIVTNSE 79

Query: 949  GFKFSKPIGDFKFG-VSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQ 1007
                S  I        S+ S    +  +S++     G S+  +N  S TP   G S    
Sbjct: 80   FHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTA-TNSESSTPSS-GASTATN 137

Query: 1008 EEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKT 1067
             +       ++S+G S  T   +ST +   +  T+   S+ + G     ++  +  + + 
Sbjct: 138  SDSS-----TTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRA 192

Query: 1068 SEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEP 1127
            S A   E   T  G S      +   S        T    +   TS+       +++  P
Sbjct: 193  STATNSESSTTSSGASTATNSESRTTSNGA----GTATNSESSTTSSGASTATNSESSTP 248

Query: 1128 KCQPVFSFGNSEQTKDE------NSSKSTFSFSMTKPSEKESEQPAK----------ATF 1171
                  +  +   T         NS  ST S  ++  +  ES  P+           +T 
Sbjct: 249  SSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTT 308

Query: 1172 AFGAQTSTTADQGAAKPVFSFLNNSSSS-----------SSTPATSAGGGIF---GSSTS 1217
            + GA T+T +D        S   NS SS           S +  TS+G       GSST+
Sbjct: 309  SSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTT 368

Query: 1218 SSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS-LLFSQDSKLATTSSTGTAVTPFVFG 1276
            SS    AT    +SS   S ++   T+ESST+ S    + +S+ +T SS  +  T     
Sbjct: 369  SSGTSTATN--SESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESS 426

Query: 1277 PGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPA 1318
              +S  NT T+    G++ TS+ +G++ + G   ++ SAS A
Sbjct: 427  TTSSGANTATNS---GSSVTSAGSGTAALTGMHTTSHSASTA 465



 Score = 70.9 bits (172), Expect = 9e-12
 Identities = 79/308 (25%), Positives = 140/308 (45%), Gaps = 21/308 (6%)

Query: 1170 TFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFG 1229
            T + G  T+T ++        S   NS SS+++   S       SST SS    AT    
Sbjct: 82   TTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNS-ESSTPSSGASTATN--S 138

Query: 1230 QSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAV-------TPFVFGPGASSN 1282
             SS   S ++    ++SST+ S   +  +  ++T+S+G +        T       A+++
Sbjct: 139  DSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNS 198

Query: 1283 NTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFG 1342
             ++T+  G    T S S  +S   GT  ++ S++ + GA+ T T  +S   S        
Sbjct: 199  ESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGAS-TATNSESSTPSSGAGTATN 257

Query: 1343 SISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTT 1402
            S SS+T+   +G+  A  +  +  SS    V   + S  + G+ T  NS S+    ++++
Sbjct: 258  SESSTTS---SGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESS----TTSS 310

Query: 1403 NFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSF 1462
              N   NS S   + GA+++T + S+  S SG      S ++ T  S+G +  ++SG+S 
Sbjct: 311  GANTATNSDSSTTSSGASTATNSESSTTS-SGASTATNSESSTT--SSGASTATNSGSST 367

Query: 1463 SGRKIKTA 1470
            +     TA
Sbjct: 368  TSSGTSTA 375



 Score = 34.3 bits (77), Expect = 0.91
 Identities = 67/312 (21%), Positives = 102/312 (32%), Gaps = 19/312 (6%)

Query: 643 SSFS--SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETP 700
           S FS  SSGI    + ++ S+         N  +         A  S   T         
Sbjct: 93  SEFSTVSSGISIATNSES-STTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTAT 151

Query: 701 NKSGKTTLSASGTGFGDKFKPVIG----TWDCDTCLVQNKPEAIKCVACETPKPGTCVKR 756
           N    TT S + T    +            + ++  V ++          T   G     
Sbjct: 152 NSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTAT 211

Query: 757 ALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSC 816
                  S  A T T S SS T +  +     +   P      +    S+        + 
Sbjct: 212 NSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTAT 271

Query: 817 MSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST-----KC 871
            SE   SS  +S  STV  S  S  S G       E S           +DS+       
Sbjct: 272 NSE---SSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGAS 328

Query: 872 LACESAKPGTKSGFK-GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQG 930
            A  S    T SG     ++ SS+++S AS++   G S++SSG   T T+T +       
Sbjct: 329 TATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSG---TSTATNSESSTVSS 385

Query: 931 GFKIGVSSDSGS 942
           G     +S+S +
Sbjct: 386 GASTATTSESST 397


>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
          Length = 987

 Score = 88.6 bits (218), Expect = 4e-17
 Identities = 149/594 (25%), Positives = 220/594 (37%), Gaps = 128/594 (21%)

Query: 823  SSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKP--- 879
            SS+P ++S+T P   P   S+G      P  S    L     K  +T   A  +  P   
Sbjct: 493  SSLPTTTSTTAPTFQPVFSSMG------PPAS--VPLPAPFFKQTTTPATAPTTTAPLFT 544

Query: 880  ---GTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGV 936
                  S      ++S S++SA+  +F FG++S SS    T TST          F  G 
Sbjct: 545  GLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTAT---AASQPFLFGA 601

Query: 937  SSDSGSINPMSEGFKFSKPIGD-FKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSL 995
                    P +    F+  +G  F+FG     KP  +   +    F   L + +    S 
Sbjct: 602  --------PQASAASFTPAMGSIFQFG-----KPPALPTTTTVTTFSQSLPTAVPTATS- 647

Query: 996  TPFQFGVSNLGQEEKKEELPKSSSAGFS-FGTGVINSTPAPANTIVTSENKSSFNLGTIE 1054
                                 SS+A FS FG+ +  S PA ++    + + +S     I 
Sbjct: 648  ---------------------SSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIP 686

Query: 1055 TKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPS-ASVFVLGRTEEKQQE--PV 1111
              S++ +P         +    A +G    G  +PA  PS  S F  G +        P 
Sbjct: 687  FGSSAKSPLPSYPGANPQPAFGAAEGQPP-GAAKPALTPSFGSSFTFGNSAAPAPATAPT 745

Query: 1112 TSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATF 1171
             + +        +     QP F            ++ S F    T               
Sbjct: 746  PAPASTIKIVPAHVPTPIQPTFG----------GATHSAFGLKATAS------------- 782

Query: 1172 AFGAQTSTTADQGAAKPVFSFLNNSSS----SSSTPATSAGGGIFGSSTSSSNPPVATFV 1227
            AFGA  S+    G +  VFSF   +SS    ++ T ++ +   +FGS+T S       F 
Sbjct: 783  AFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSP------FT 836

Query: 1228 FGQSSNPVSSSAFG-NTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTT 1286
            FG S+ P  S +FG N A   +S           ATT +       F FG G S +  T+
Sbjct: 837  FGGSAAPAGSGSFGINVATPGSS-----------ATTGA-------FSFGAGQSGSTATS 878

Query: 1287 SGF--GFGATTTSSSAGSS-FVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGS 1343
            + F  G G     ++  S+ F F  G S   + P FG   TPTFGQ+  A     PG G+
Sbjct: 879  TPFTGGLGQNALGTTGQSTPFAFNVG-STTESKPVFGGTATPTFGQNTPA-----PGVGT 932

Query: 1344 ISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGT-TPNSSSAFQ 1396
             S S+  F   S PA    G     S  P F       + G+G+ TP +    Q
Sbjct: 933  -SGSSLSFGASSAPAQGFVGVGPFGSAAPSF-------SIGAGSKTPGARQRLQ 978



 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 139/501 (27%), Positives = 195/501 (38%), Gaps = 138/501 (27%)

Query: 1064 TCKTSEAKKEEMPATKGGFSFG--NVEPAS--LPSAS--------VFVLGRTEEKQQEP- 1110
            T    +A     PA K  F FG  N  P+S   P+AS        +F      EK+    
Sbjct: 421  TATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTP 480

Query: 1111 ----VTST---SLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKES 1163
                VT+T   S           P  QPVFS           S     S  +  P  K++
Sbjct: 481  PGPSVTATAPSSSSLPTTTSTTAPTFQPVFS-----------SMGPPASVPLPAPFFKQT 529

Query: 1164 EQPA--------------KATFAFGAQTSTT-ADQGAAKPVFSFLNNSSSSSSTPATSAG 1208
              PA               AT A    TS + +   A+KP F F  NS SSSS   T++ 
Sbjct: 530  TTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTS- 588

Query: 1209 GGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGT 1268
                 ++T++S P    F+FG    P +S+A    A  S  Q   F +   L TT++  T
Sbjct: 589  -----TATAASQP----FLFGA---PQASAASFTPAMGSIFQ---FGKPPALPTTTTVTT 633

Query: 1269 AVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSS--------------FVFGTGPSAPS 1314
                       +++++     GFG+T  +S+  +S              F    G SA S
Sbjct: 634  FSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKS 693

Query: 1315 ASPAF-GANQTPTFG----QSQGASQPN-PPGFGS---ISSSTALFP-TGSQPAP----- 1359
              P++ GAN  P FG    Q  GA++P   P FGS     +S A  P T   PAP     
Sbjct: 694  PLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIK 753

Query: 1360 -----------PTFGTVSSS---------------SQPPVFGQQPSQSAFGSGTTPNSSS 1393
                       PTFG  + S               S  P FG   +  +FG+ T+    +
Sbjct: 754  IVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGA 813

Query: 1394 AFQF---GSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFN-------QSPA 1443
              Q    GSS++ F  T  SP   FTFG        SA P+GSG F  N        +  
Sbjct: 814  TTQTASSGSSSSVFGSTTPSP---FTFG-------GSAAPAGSGSFGINVATPGSSATTG 863

Query: 1444 AFTVGSNGKNVFSSSGTSFSG 1464
            AF+ G+ G++  +++ T F+G
Sbjct: 864  AFSFGA-GQSGSTATSTPFTG 883



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 113/472 (23%), Positives = 185/472 (39%), Gaps = 76/472 (16%)

Query: 1033 PAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASL 1092
            PAP     T+   +      + T  AS        + A      A+K  F FG     S+
Sbjct: 522  PAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGI---NSV 578

Query: 1093 PSASVFVLGRTEEKQQEPVTSTSLVFGK---KADNEEPKCQPVFSFGNSEQTKDENSSKS 1149
             S+SV     T     +P      +FG     A +  P    +F FG         ++ +
Sbjct: 579  SSSSVSTTTSTATAASQP-----FLFGAPQASAASFTPAMGSIFQFGKPPALPT-TTTVT 632

Query: 1150 TFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGG 1209
            TFS S+       +   A     FG+  +T+A   +++P  +F N S+ + + P  S+  
Sbjct: 633  TFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAK 692

Query: 1210 GIFGSSTSSSNPPVATFVFGQ---SSNPVSSSAFGN--TAESSTSQSLLFSQDSKLATTS 1264
                S   ++  P      GQ   ++ P  + +FG+  T  +S + +   +     A+T 
Sbjct: 693  SPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTI 752

Query: 1265 STGTAVTPFVFGP---GASSN----NTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASP 1317
                A  P    P   GA+ +      T S FG  A++  +  GS+ VF  G +  S   
Sbjct: 753  KIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSG-- 810

Query: 1318 AFGAN-QTPTFGQSQ---GASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPV 1373
             FGA  QT + G S    G++ P+P  FG  ++     P GS        T  SS+    
Sbjct: 811  -FGATTQTASSGSSSSVFGSTTPSPFTFGGSAA-----PAGSGSFGINVATPGSSATTGA 864

Query: 1374 FGQQPSQSAFGSGTTPNSSS----------------------AFQFGSSTTNF------- 1404
            F       +FG+G + ++++                      AF  GS+T +        
Sbjct: 865  F-------SFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTA 917

Query: 1405 --NFTNNSPS-GVFTFGANSSTPAASAQPSGSGGF-PFNQSPAAFTVGSNGK 1452
               F  N+P+ GV T G++ S  A+SA   G  G  PF  +  +F++G+  K
Sbjct: 918  TPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAPSFSIGAGSK 969



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 203/927 (21%), Positives = 298/927 (32%), Gaps = 204/927 (22%)

Query: 436  NGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEIT 495
            N  S    G  G+ R+ + + + S+    E++ +P  P++   IT+  L     +S +  
Sbjct: 226  NSNSQSTPGSSGQ-RKRKVQLLPSR--RGEQLTLPPPPQLGYSITAEDLDLEKKASLQWF 282

Query: 496  TSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAK 555
              +    + S A +N V  T P  T  P F F+ P      A   PP+S+    + P+ +
Sbjct: 283  NQALE--DKSDAASNSVTETPP--TTQPSFTFTLP----AAATASPPTSLLAPSTNPLLE 334

Query: 556  TAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPAEILKEGSVLDILKSP 615
            + +   +  +L P   S+     T  + +  KTP         P   L +     +L SP
Sbjct: 335  SLKKMQTPPSLPPCPESAG--AATTEALSPPKTP------SLLPPLGLSQSGPPGLLPSP 386

Query: 616  GFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTD 675
             F S    ++     A S V  T                  KA  + Q +T         
Sbjct: 387  SFDSKPPTTLLGLIPAPSMVPAT----------------DTKAPPTLQAETATKPQ---- 426

Query: 676  NKCIACQAAKLSPRDTAKQTGI-ETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQ 734
                    A  +P    KQ+ +  T N S  +  + + +     FKP+       T   +
Sbjct: 427  --------ATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIF------TAPPK 472

Query: 735  NKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPI 794
            ++ E        TP PG  V    T T  S S+   T S+++ T             +P+
Sbjct: 473  SEKEG------PTP-PGPSV----TATAPSSSSLPTTTSTTAPTF------------QPV 509

Query: 795  GSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASS----SSTVPVSLPSGGSLGLEKFKK 850
             S                     S  P +SVP  +     +T P + P+           
Sbjct: 510  FS---------------------SMGPPASVPLPAPFFKQTTTPATAPT----------- 537

Query: 851  PEGSWDCELCLVQNKADSTKCLA-CESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSS 909
                      L    A +T  +A   SA P T S              A+  +F FG++S
Sbjct: 538  ------TTAPLFTGLASATSAVAPITSASPSTDS--------------ASKPAFGFGINS 577

Query: 910  SSSGPSQTLTSTGN-----FKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIG---DFKF 961
             SS    T TST       F FG         +   GSI      F+F KP         
Sbjct: 578  VSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSI------FQFGKPPALPTTTTV 631

Query: 962  GVSSESKPEEV---KKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQ--------EEK 1010
               S+S P  V      S  D   FG +   S P + +      SN              
Sbjct: 632  TTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSA 691

Query: 1011 KEELPKSSSAGFSFGTGVI-NSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSE 1069
            K  LP    A      G      P  A   +T    SSF  G     + + AP     S 
Sbjct: 692  KSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPAST 751

Query: 1070 AKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEP-- 1127
             K               + PA +P+      G         + +T+  FG  A ++    
Sbjct: 752  IK---------------IVPAHVPTPIQPTFGGATH-SAFGLKATASAFGAPASSQPAFG 795

Query: 1128 KCQPVFS--------FGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTST 1179
                VFS        FG + QT    SS S F  +   P           + +FG   +T
Sbjct: 796  GSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVAT 855

Query: 1180 TADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSA 1239
                 A    FSF    S S++T     GG   G +   +      F F   S   S   
Sbjct: 856  PG-SSATTGAFSFGAGQSGSTATSTPFTGG--LGQNALGTTGQSTPFAFNVGSTTESKPV 912

Query: 1240 FGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSS 1299
            FG TA  +  Q+           T + G   +      GASS        GF       S
Sbjct: 913  FGGTATPTFGQN-----------TPAPGVGTSGSSLSFGASS----APAQGFVGVGPFGS 957

Query: 1300 AGSSFVFGTGPSAPSASPAFGANQTPT 1326
            A  SF  G G   P A     A +  T
Sbjct: 958  AAPSFSIGAGSKTPGARQRLQARRQHT 984



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 141/619 (22%), Positives = 224/619 (36%), Gaps = 126/619 (20%)

Query: 887  GFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPM 946
            G +      +S+ S    F    +S  P+  +   G+ K G      +   S    +N  
Sbjct: 70   GQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRG------LNSQSSDDHLNKR 123

Query: 947  SEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSS-GLSNPVSLTPFQFGVSNL 1005
            S     S   G +  G+ S S+       S       G+S     N  S +PF    S+ 
Sbjct: 124  SRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTR----GISQLWKRNGPSSSPFSSPASSR 179

Query: 1006 GQEEKK-------EELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSA 1058
             Q  ++       EEL   SS+          STP  A+     E  +       +  ++
Sbjct: 180  SQTPERPAKKIREEELCHHSSS----------STPLAADKESQGEKAADTTPRKKQNSNS 229

Query: 1059 SVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVF 1118
               P +    + K + +P+ +G       E  +LP      LG +       +T+  L  
Sbjct: 230  QSTPGSSGQRKRKVQLLPSRRG-------EQLTLPPPPQ--LGYS-------ITAEDLDL 273

Query: 1119 GKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKES---EQPAKATFAFGA 1175
             KKA           S     Q  ++ S  ++ S + T P+ + S     PA AT    A
Sbjct: 274  EKKA-----------SLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAAT----A 318

Query: 1176 QTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVF-----GQ 1230
               T+    +  P+   L    +  S P      G   ++T + +PP    +       Q
Sbjct: 319  SPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAG--AATTEALSPPKTPSLLPPLGLSQ 376

Query: 1231 SSNP--VSSSAFGNTAESST-----SQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNN 1283
            S  P  + S +F +   ++      + S++ + D+K   T    TA  P      ++ + 
Sbjct: 377  SGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQAT---SAPSP 433

Query: 1284 TTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQT-PTFGQSQGASQPNPPGFG 1342
                 F FG   TS S+ ++      P+A SASP F    T P   + +G + P P    
Sbjct: 434  APKQSFLFGTQNTSPSSPAA------PAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTA 487

Query: 1343 SISSSTALFPTGSQPAPPTFGTVSSSSQPPV-------FGQQPSQSAFGSGTT------- 1388
            +  SS++L PT +    PTF  V SS  PP        F +Q +  A    TT       
Sbjct: 488  TAPSSSSL-PTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGL 546

Query: 1389 --------------PNSSS----AFQFG------SSTTNFNFTNNSPSGVFTFGANSSTP 1424
                          P++ S    AF FG      SS +    T  + S  F FGA  ++ 
Sbjct: 547  ASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQAS- 605

Query: 1425 AASAQPSGSGGFPFNQSPA 1443
            AAS  P+    F F + PA
Sbjct: 606  AASFTPAMGSIFQFGKPPA 624


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 301/1457 (20%), Positives = 491/1457 (33%), Gaps = 166/1457 (11%)

Query: 69   STDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTR 128
            S D       P      ++  D   S I+ G +       +T +P  +  ++ +      
Sbjct: 73   SPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRS 132

Query: 129  PSLHRSHLNFSML------ESPALHCQPSTS--SAFPIGSSGFSLVKEIKDSTSQHDDDN 180
            P    +HL  SM       ES   H +P ++  +AFP  ++   L +E   ST+ H    
Sbjct: 133  PDT--THLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQE---STASH---- 183

Query: 181  ISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLS 240
                    S     D T+S  ++      PE    HS    T T+      N +A G L 
Sbjct: 184  --------SSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPD--NTTASGLLE 233

Query: 241  PSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQS 300
             S+   S  ++     SP   G TT  G +              AP        + S  S
Sbjct: 234  ASMPVHSSTRSPHTTLSP--AGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTS 291

Query: 301  YGVTSS------TARRILQSLEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKR 354
            +G  SS      +AR     L + S+    +      +  P +      G + T   +  
Sbjct: 292  HGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSST 351

Query: 355  EKVDSQYPPVQRLMTPKPVSI----ATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEK 410
                S  P     +  +P S      +  + +F  S T SG   ++     ++ +TG   
Sbjct: 352  THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATG--- 408

Query: 411  NMTPGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVP 470
                                 LPA +  S  +G               + P+    ME  
Sbjct: 409  ------------------TIVLPARSTTSVLLGES------------TTSPISSGSMETT 438

Query: 471  VLP-KISLPITSSSLPTFNFS--SPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKF 527
             LP   + P  S    TF+ S  SP  T S  S  +S  +  +    + P ST +  F  
Sbjct: 439  ALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPD 498

Query: 528  SSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSS--STLEPIISSSAHHVTTVNSTNC 585
            S+     +  +    SS G T +  +  +   SG S  ST     S S     +  ST  
Sbjct: 499  STTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTA 558

Query: 586  KKTPPEDCEGPFRPAEILKEGSVLDILKSPGF--ASPKIDSVAAQPTAT-SPVVYTRPAI 642
                 E       P          D   S G   AS ++ S    P  T SP   T P +
Sbjct: 559  LSFGQESTTFHSNPGST-HTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL 617

Query: 643  SSFSSSGIGFGESLKAGSSWQCD-TCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPN 701
               S++      S     S     T  ++   T ++          P  +       T  
Sbjct: 618  QGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASST------TSG 671

Query: 702  KSGKTTL-----SASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKR 756
             S K+T+      ASGT          G  +  T  +      I  +   T  PG  +  
Sbjct: 672  HSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPG--LSE 729

Query: 757  ALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSC 816
            A T    S  + T T S +S T    +LG G++          +   VS  +     +S 
Sbjct: 730  ASTTFYSSPRSPTTTLSPASMT----SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSE 785

Query: 817  MSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACES 876
             S    SS   S+ +TV     +    G E              L    + ++      +
Sbjct: 786  ESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEEST 845

Query: 877  AKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQT-LTSTGNFKFGDQGGFKIG 935
            A PG+ +  +    ++ ++      S  F  SS S+G   +   ST +   G+    ++ 
Sbjct: 846  AFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLS 905

Query: 936  VSSD----------SGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGL 985
             SS           + S++  S  F  S    D     ++ +    V ++S   + + G 
Sbjct: 906  PSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS-SGVSEESSTSHSQPGS 964

Query: 986  SSGLSNPVSLTPFQFG----VSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVT 1041
            +   + P S T          S+  Q   +  L   S+   S G        +P +T  T
Sbjct: 965  THTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETT 1024

Query: 1042 SENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPA--TKGGFSFGNVEPASLPSASVFV 1099
                 +   G +E  +    P    T        PA  T  G    +    S PS+S   
Sbjct: 1025 LLPDDTITSGLVEAST----PTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSS--- 1077

Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPS 1159
                +     P T+ + V      +  P   P   F  S  T   +   +T   S     
Sbjct: 1078 ----DTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSS----- 1128

Query: 1160 EKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSS 1219
                     A F   + TS    +    P+ S    S+ +++ P ++   G+   ST+  
Sbjct: 1129 ---PGATGTALFPTRSATSVLVGEPTTSPISS---GSTETTALPGSTTTAGLSEKSTTFY 1182

Query: 1220 NPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGA 1279
            + P +      + +P S+++ G + ES+TS S    +     TT+  G+   P V     
Sbjct: 1183 SSPRSP---DTTLSPASTTSSGVSEESTTSHS----RPGSTHTTAFPGSTTMPGV----- 1230

Query: 1280 SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQT---PTFGQSQGASQP 1336
             S  +T S    G+T T+ S GS+     GP + +   + G+ +T   P    + G  + 
Sbjct: 1231 -SQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEA 1289

Query: 1337 NPPGFGSISS-STALFPTGS---QPAPPTFGTVSSSSQ----PPVFGQQPSQSAFGSGTT 1388
            + P   S  S  T L P GS   Q    TF +  SS      PP       + +  S  +
Sbjct: 1290 STPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGS 1349

Query: 1389 PNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVG 1448
            P+S+    F +S+T    +  S +   +  A ++TP  S   S + G     +    + G
Sbjct: 1350 PSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTP--SPARSTTSGLVEESTAYHSSPG 1407

Query: 1449 SNGKNVFSSSGTSFSGR 1465
            S     F  S T+ SGR
Sbjct: 1408 STQTMHFPESSTA-SGR 1423



 Score = 78.2 bits (191), Expect = 6e-14
 Identities = 261/1252 (20%), Positives = 444/1252 (35%), Gaps = 153/1252 (12%)

Query: 256  DSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSL 315
            +S  + G TT+  ++     + L +T Y + +          + +    S  ++    S 
Sbjct: 15   ESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSP 74

Query: 316  EKMSSPLADAKRIPSI-VSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVS 374
            + M++ +  A   PS+ V     SP+    ++ T       K     P +    T    S
Sbjct: 75   DAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTK-----PGLSEKSTTFYSS 129

Query: 375  IATNRSVYFKPSLTPSG---EFRKTNQRIDNKCSTGYEKNMT-PGQNREQRESGFSYPNF 430
              +  + +   S+T SG   E   ++ R  +  +T +  + T PG ++E   S  S P  
Sbjct: 130  PRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTAS-HSSPG- 187

Query: 431  SLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFS 490
              P    LS G       +  E T F  S+P   E   +P     S  +  +S+P  + +
Sbjct: 188  --PTDTTLSPG-STTASSLGPEYTTF-HSRPGSTETTLLPDNTTAS-GLLEASMPVHSST 242

Query: 491  SPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPS--SIGFT 548
                TT SP+   + Q         S +    P  K + P   +T +  + PS  S G  
Sbjct: 243  RSPHTTLSPAGSTTRQG-------ESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSP 295

Query: 549  FSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDC-EGPFRPAEILKEGS 607
             S+P   T  +S  S+T   +  S+ +H ++  ST     P  D   G    +      +
Sbjct: 296  SSIP---TTHISARSTTSGLVEESTTYH-SSPGSTQTMHFPESDTTSGRGEESTTSHSST 351

Query: 608  VLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTC 667
               I  +P   S  ++   +  ++      T    SS +S   G  E   A  S Q  T 
Sbjct: 352  THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTS---GRSEESTASHSSQDATG 408

Query: 668  LLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWD 727
             +         +    +  SP  +        P  +    LS   T F            
Sbjct: 409  TIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTF------------ 456

Query: 728  CDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTV-VSESAETMTASSSSCTVTTGTLGF 786
                   + P +          P T +  A T +  VSE + T  +   S    T T  F
Sbjct: 457  ------HSSPRS----------PATTLSPASTTSSGVSEESTTSRSRPGS----THTTAF 496

Query: 787  GDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPG----SSVPASSSSTVPVSLPSGGS 842
             D    P  S   +    S  + D   +   +   G    S+   SSS +   +L  G +
Sbjct: 497  PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGST 556

Query: 843  LGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSS 902
              L        S+  E     +   ST                  F  S++SS    +S+
Sbjct: 557  TAL--------SFGQESTTFHSNPGSTHTTL--------------FPDSTTSSGIVEAST 594

Query: 903  FKFGVSSSSSGPSQTLTSTGNFKFGDQG---GFKIGVSSD-------SGSINPMSEGFKF 952
                V SS+  P  TL+   +   G QG    F+   +S        S +  P+ E   +
Sbjct: 595  ---RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTY 651

Query: 953  SKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKE 1012
             +  G      S+ +        +   + K  +     +    TP     +  G+ E   
Sbjct: 652  HRSPG------STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGE--- 702

Query: 1013 ELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKK 1072
                S+++  S G+  I + P    T   SE  ++F   +  + + +++P +  TS    
Sbjct: 703  ----STTSRISPGSTEITTLPGSTTTPGLSEASTTF-YSSPRSPTTTLSPASM-TSLGVG 756

Query: 1073 EEMPATKG--GFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQ 1130
            EE   ++   G +   V PAS  +  +     T        T T+ VF           +
Sbjct: 757  EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETT-VFPHSTTTSVHGEE 815

Query: 1131 PVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVF 1190
            P         T     ++ + +  +T+ S      PA       A T TTAD G     F
Sbjct: 816  PTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPA-TLTTADLGEESTTF 874

Query: 1191 SFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQ 1250
               + S+ +  +PA S   G+ G ST S   P +T       +P + S    + +S+T  
Sbjct: 875  PSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSL---SEKSTTFY 931

Query: 1251 SLLFSQDSKL--ATTSSTGTA-------VTPFVFGPGASSNNTTTSGFGFGATTTSSSAG 1301
            +   S D+ L  ATT+S+G +         P      A  ++TTTS      TT+ SS G
Sbjct: 932  TSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQG 991

Query: 1302 SSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPT 1361
            S+      P + +AS      Q+ TF  S G ++       +I+S      T +  +  +
Sbjct: 992  STEA-TLSPGSTTASSL--GQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGS 1048

Query: 1362 FGTVSSSSQPPVFGQQPSQSAF-----GSGTTPN--SSSAFQFGSSTTNFNFTNNSPSGV 1414
              T  + +     G Q   + F      S TTP+   ++A     STT  +  +++P+  
Sbjct: 1049 LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTH 1108

Query: 1415 F-----TFGANSSTPAASAQPSGSGGFPF-NQSPAAFTVGSNGKNVFSSSGT 1460
            F     T G +  +    + P  +G   F  +S  +  VG    +  SS  T
Sbjct: 1109 FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGST 1160



 Score = 70.9 bits (172), Expect = 9e-12
 Identities = 284/1342 (21%), Positives = 457/1342 (34%), Gaps = 171/1342 (12%)

Query: 93   SSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPST 152
            S+  T   +  EP   ++   ST +T  ++PD  T     RS       ES A H     
Sbjct: 357  SAPSTTSALVEEPTSYHSSPGSTATT--HFPDSSTTSG--RSE------ESTASHSSQDA 406

Query: 153  SSAFPIGSSGFSLVKEIKDSTSQHDDDNISTT----SGFSSRASDKDITVSKNTSLPPLW 208
            +    + +   + V   + +TS     ++ TT    S  +   S++  T   +   P   
Sbjct: 407  TGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATT 466

Query: 209  -SPEAERSHSLSQHTATSSKKP-AFNLSAF--GTLSPSLGNSSILKTSQLG--DSPFYPG 262
             SP +  S  +S+ + TS  +P + + +AF   T +P L   S    S  G  D+   P 
Sbjct: 467  LSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 526

Query: 263  KTTYGG----AAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQSLEKM 318
             TT  G    +  +   S   +T         +   Q S   +    ST   +       
Sbjct: 527  STTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTS 586

Query: 319  SSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVSIATN 378
            S  +  + R+ S   SP  +    S    T    + E    Q  P     TP P S AT 
Sbjct: 587  SGIVEASTRVHSSTGSPRTTLSPASS---TSPGLQGESTAFQTHPASTHTTPSPPSTAT- 642

Query: 379  RSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYPNFSLPAANGL 438
                      P  E    ++   +  +T +  + T   + E+     S P+ S    +  
Sbjct: 643  ---------APVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSA 693

Query: 439  SSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSS 498
             S   G G            +  +     E+  LP  +     S   T  +SSP   T++
Sbjct: 694  HSTTSGRGES---------TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTT 744

Query: 499  PSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAE 558
             SP + +     +   TS S  GS            T + V P S+           T  
Sbjct: 745  LSPASMTSLGVGEESTTSRSQPGS------------THSTVSPASTT----------TPG 782

Query: 559  LSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPAE----ILKEGSVLDILKS 614
            LS  S+T+      S       +ST       E      RPA     +  E S    L  
Sbjct: 783  LSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTE 842

Query: 615  PGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVT 674
               A P        P +T   +   PA  + +++ +G   +    SS    T L   + T
Sbjct: 843  ESTAFP------GSPASTQTGL---PA--TLTTADLGEESTTFPSSSGSTGTKLSPARST 891

Query: 675  DNKCIA-CQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLV 733
             +  +     ++LSP  T   T    P      +LS   T F    +    T    T   
Sbjct: 892  TSGLVGESTPSRLSPSSTETTT---LPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 948

Query: 734  QNKPEAIKCVACETPKPGTCVKRALT-LTVVSESAETMTASSSSCTVTTGTLGFGDKFKR 792
                E     +    +PG+    A    T  S+ ++  T S SS   T  TL  G     
Sbjct: 949  SGVSEES---STSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTAS 1005

Query: 793  PIGSWECSVCCVSNNAE-----DNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEK 847
             +G    +      + E     D+   S + E    +  ++ S    ++  S  S GL++
Sbjct: 1006 SLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQE 1065

Query: 848  FKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGV 907
                  SW        + +D+T      +A P   S       SS+ +   ++SS   G 
Sbjct: 1066 ESTTFQSWP-------SSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGR 1118

Query: 908  SSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSK--PIGDFKFGVSS 965
            S  S+    +  +TG   F  +    + V   + S  P+S G   +   P      G+S 
Sbjct: 1119 SEESTTVHSSPGATGTALFPTRSATSVLVGEPTTS--PISSGSTETTALPGSTTTAGLSE 1176

Query: 966  ESKPEEVKKDSKNDNFKFG--LSSGLSNPVSLTPFQFGVSNLGQEEKKEELP---KSSSA 1020
            +S        S +         SSG+S   + +  + G ++         +P   + S+A
Sbjct: 1177 KSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTA 1236

Query: 1021 GFSFGTGVINSTPAPANTIVTSENKSSFNL----GTIETKSASVAPFTCKTSEAKKEEMP 1076
              S   G  ++T +P +T  +S    S       G+ ET   ++ P     S   +   P
Sbjct: 1237 SHS-SPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTET---TLLPDNTTASGLLEASTP 1292

Query: 1077 ATKGGFSFGNVEPASLPSASVFVLGRTEEKQQ----------EPVTSTSLVFGKKADNEE 1126
                  S G+      P+ S    G +   Q            P T+++ V      +  
Sbjct: 1293 VHS---STGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGS 1349

Query: 1127 PKCQPVFSFGNSEQTKDENSSKSTFSFS----MTKPSEKES-------EQPAKATFAFGA 1175
            P   P   F  S  T   +   +T   S     T PS   S       E  A  +     
Sbjct: 1350 PSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGST 1409

Query: 1176 QT-----STTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQ 1230
            QT     S+TA   + +   S  + + + SS P+T++      +S  SS   +AT  F  
Sbjct: 1410 QTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHF-- 1467

Query: 1231 SSNPVSSSAFGNTAESSTSQSLLFSQDSK-------LATTSSTGTAVTPFVFGPGAS--- 1280
               P SS+  G + ES+ S S   S D+          TTS      T F   PG+    
Sbjct: 1468 ---PESSTTSGRSEESTASHS---SPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETT 1521

Query: 1281 -SNNTTTSGFGFGATT--TSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPN 1337
             ++  TT G    +T   TS   G    F   PS P+ +  F A+ + +    +  +   
Sbjct: 1522 LASTATTPGLSAKSTILYTSDLVGEPTTFYISPS-PTYTTLFPASSSTSGLTEESTTFHT 1580

Query: 1338 PPGFGSISSSTALFPTGSQPAP 1359
             P F S   ST    T +   P
Sbjct: 1581 SPSFTSTIVSTESLETLAPETP 1602



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 108/497 (21%), Positives = 190/497 (38%), Gaps = 59/497 (11%)

Query: 1003 SNLGQEEKKEELPKSSSAGFSFGTGVINSTP-APANTIVTSENKSSFNLGTIETKSASVA 1061
            S+LG  E       S+ +G S  +   +S+P A A T++ + +  S  +G      ++ +
Sbjct: 44   SSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVG-----DSTPS 98

Query: 1062 PFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKK 1121
            P +  + E        TK G S  +    S P        R+ +    P + TS    ++
Sbjct: 99   PISSGSMETTALPGSTTKPGLSEKSTTFYSSP--------RSPDTTHLPASMTSSGVSEE 150

Query: 1122 A--DNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTST 1179
            +   +  P      +F  S  T    S +ST S S   P++      +    + G + +T
Sbjct: 151  STTSHSRPGSTHTTAFPGST-TMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTT 209

Query: 1180 TADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSN------ 1233
               +  +       +N+++S    A+        S  ++ +P  +T   G+S+       
Sbjct: 210  FHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPS 269

Query: 1234 --------PVSSSAF--GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSN- 1282
                    P ++SAF   +T    +  S+  +  S  +TTS      T +   PG++   
Sbjct: 270  SKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTM 329

Query: 1283 ----NTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSA----------SPAFGANQTPTFG 1328
                + TTSG G  +TT+ SS  ++    + PS  SA          SP  G+  T  F 
Sbjct: 330  HFPESDTTSGRGEESTTSHSS--TTHTISSAPSTTSALVEEPTSYHSSP--GSTATTHFP 385

Query: 1329 QSQGASQPNPPGFGSISSSTALFPTGS--QPAPPTFGTV--SSSSQPPVFGQQPSQSAFG 1384
             S   S  +     S SS  A   TG+   PA  T   +   S++ P   G   + +  G
Sbjct: 386  DSSTTSGRSEESTASHSSQDA---TGTIVLPARSTTSVLLGESTTSPISSGSMETTALPG 442

Query: 1385 SGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAA 1444
            S TTP  S       S+     T  SP+   + G +  +  + ++P  +    F  S   
Sbjct: 443  STTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTT 502

Query: 1445 FTVGSNGKNVFSSSGTS 1461
              +  +     SS G++
Sbjct: 503  PGLSRHSTTSHSSPGST 519


>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
          Length = 984

 Score = 84.3 bits (207), Expect = 8e-16
 Identities = 142/595 (23%), Positives = 209/595 (35%), Gaps = 133/595 (22%)

Query: 823  SSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKP--- 879
            SS+P ++S+T P   P   S+G      P  S    L     K  +T   A  +  P   
Sbjct: 493  SSLPTTTSTTAPTFQPVFSSMG------PPAS--VPLPAPFFKQTTTPATAPTTTAPLFT 544

Query: 880  ---GTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGN-----FKFGDQGG 931
                  S      ++S S++SA+  +F FG++S SS    T TST       F FG    
Sbjct: 545  GLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG---- 600

Query: 932  FKIGVSSDSGSINPMSEGFKFSKPIGD-FKFGVSSESKPEEVKKDSKNDNFKFGLSSGLS 990
                         P +    F+  +G  F+FG     KP  +   +    F   L + + 
Sbjct: 601  ------------APQASAASFTPAMGSIFQFG-----KPPALPTTTTVTTFSQSLHTAVP 643

Query: 991  NPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFS-FGTGVINSTPAPANTIVTSENKSSFN 1049
               S                      SS+A FS FG+ +  S PA ++    + + +S  
Sbjct: 644  TATS----------------------SSAADFSGFGSTLATSAPATSSQPTLTFSNTSTP 681

Query: 1050 LGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPS-ASVFVLGRTEEKQQ 1108
               I   S++ +P         +    A +G    G  +PA  PS  S F  G +     
Sbjct: 682  TFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQ-PPGAAKPALAPSFGSSFTFGNSAAPAA 740

Query: 1109 EPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAK 1168
             P  +   +             P+F            ++ S F    T            
Sbjct: 741  APTPAPPSMIKVVPAYVPTPIHPIFG----------GATHSAFGLKAT------------ 778

Query: 1169 ATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGG---GIFGSSTSSSNPPVAT 1225
               AFGA  S+    G +  VF     SS   +T  T++ G    +FGS+T S       
Sbjct: 779  -ASAFGAPASSQPAFGGSTAVFFGAATSSGFGATTQTASSGSSSSVFGSTTPS------P 831

Query: 1226 FVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTT 1285
            F FG S+ P  S +FG                     T  + T    F FG G S +  T
Sbjct: 832  FTFGGSAAPAGSGSFGIN-----------------VATPGSSTTTGAFSFGAGQSGSTAT 874

Query: 1286 TSGF--GFGATTTSSSAGSS-FVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFG 1342
            ++ F  G G     ++  S+ F F    S   + P FG   TPTFG +  A     PG G
Sbjct: 875  STPFAGGLGQNALGTTGQSTPFAFNVS-STTESKPVFGGTATPTFGLNTPA-----PGVG 928

Query: 1343 SISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGT-TPNSSSAFQ 1396
            + S S+  F   S PA    G          FG      + G+G+ TP +    Q
Sbjct: 929  T-SGSSLSFGASSAPAQGFVGVAP-------FGSAALSFSIGAGSKTPGARQRLQ 975



 Score = 83.6 bits (205), Expect = 1e-15
 Identities = 138/471 (29%), Positives = 194/471 (41%), Gaps = 101/471 (21%)

Query: 1064 TCKTSEAKKEEMPATKGGFSFG--NVEPAS--LPSAS--------VFVLGRTEEKQQEP- 1110
            T    +A     PA K  F FG  N  P+S   P+AS        +F      EK+    
Sbjct: 421  TATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSAPPMFKPIFTAPPKSEKEGPTP 480

Query: 1111 ----VTST---SLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKES 1163
                VT+T   S           P  QPVFS           S     S  +  P  K++
Sbjct: 481  PGPSVTATAPSSSSLPTTTSTTAPTFQPVFS-----------SMGPPASVPLPAPFFKQT 529

Query: 1164 EQPA--------------KATFAFGAQTSTT-ADQGAAKPVFSFLNNSSSSSSTPATSAG 1208
              PA               AT A    TS + +   A+KP F F  NS SSSS   T++ 
Sbjct: 530  TTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTS- 588

Query: 1209 GGIFGSSTSSSNPPVATFVFG--QSSNPVSSSAFGNT-------AESSTSQSLLFSQDSK 1259
                 ++T++S P    F+FG  Q+S    + A G+        A  +T+    FSQ   
Sbjct: 589  -----TATAASQP----FLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLH 639

Query: 1260 LATTSSTGTAVTPFV-FGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPA 1318
             A  ++T ++   F  FG   +++   TS       T S+++  +F    G SA S  P+
Sbjct: 640  TAVPTATSSSAADFSGFGSTLATSAPATSSQP--TLTFSNTSTPTFNIPFGSSAKSPLPS 697

Query: 1319 F-GANQTPTFG----QSQGASQPN-PPGFGSI-----SSSTALFPTGSQPAPPTFGTVSS 1367
            + GAN  P FG    Q  GA++P   P FGS      S++ A  PT   PAPP+   V  
Sbjct: 698  YPGANPQPAFGAAEGQPPGAAKPALAPSFGSSFTFGNSAAPAAAPT---PAPPSMIKVVP 754

Query: 1368 SSQP----PVFGQQPSQSAFGSGTTPNS-----SSAFQFGSSTTNFNFTNNSPSGVFTFG 1418
            +  P    P+FG   + SAFG   T ++     SS   FG ST  F F   + SG   FG
Sbjct: 755  AYVPTPIHPIFGGA-THSAFGLKATASAFGAPASSQPAFGGSTAVF-FGAATSSG---FG 809

Query: 1419 ANSSTPAASAQPSGSGG-----FPFNQSPAAFTVGSNGKNVFSSSGTSFSG 1464
            A + T ++ +  S  G      F F  S A    GS G NV +   ++ +G
Sbjct: 810  ATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSTTTG 860



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 113/473 (23%), Positives = 178/473 (37%), Gaps = 81/473 (17%)

Query: 1033 PAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASL 1092
            PAP     T+   +      + T  AS        + A      A+K  F FG     S+
Sbjct: 522  PAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGI---NSV 578

Query: 1093 PSASVFVLGRTEEKQQEPVTSTSLVFGK---KADNEEPKCQPVFSFGNSEQTKDENSSKS 1149
             S+SV     T     +P      +FG     A +  P    +F FG         ++ +
Sbjct: 579  SSSSVSTTTSTATAASQP-----FLFGAPQASAASFTPAMGSIFQFGKPPALPT-TTTVT 632

Query: 1150 TFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGG 1209
            TFS S+       +   A     FG+  +T+A   +++P  +F N S+ + + P  S+  
Sbjct: 633  TFSQSLHTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAK 692

Query: 1210 GIFGSSTSSSNPPVATFVFGQ---SSNPV------SSSAFGNTAESSTSQSLLFSQDSKL 1260
                S   ++  P      GQ   ++ P       SS  FGN+A  + + +       K+
Sbjct: 693  SPLPSYPGANPQPAFGAAEGQPPGAAKPALAPSFGSSFTFGNSAAPAAAPTPAPPSMIKV 752

Query: 1261 ATTSSTGTAVTPFVFGPGASSN---NTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASP 1317
               +   T + P +FG    S      T S FG  A++  +  GS+ VF       + S 
Sbjct: 753  VP-AYVPTPIHP-IFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVF----FGAATSS 806

Query: 1318 AFGAN-QTPTFGQSQ---GASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPV 1373
             FGA  QT + G S    G++ P+P  FG  ++     P GS        T  SS+    
Sbjct: 807  GFGATTQTASSGSSSSVFGSTTPSPFTFGGSAA-----PAGSGSFGINVATPGSSTTTGA 861

Query: 1374 FGQQPSQSAFGSGT--------------------TPNSSSAFQF-------------GSS 1400
            F       +FG+G                     T   S+ F F             G++
Sbjct: 862  F-------SFGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVSSTTESKPVFGGTA 914

Query: 1401 TTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGF-PFNQSPAAFTVGSNGK 1452
            T  F     +P GV T G++ S  A+SA   G  G  PF  +  +F++G+  K
Sbjct: 915  TPTFGLNTPAP-GVGTSGSSLSFGASSAPAQGFVGVAPFGSAALSFSIGAGSK 966



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 132/586 (22%), Positives = 206/586 (35%), Gaps = 79/586 (13%)

Query: 496  TSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAK 555
            TS+PSP    Q+     Q TSPSS  +P    + P+ K       PP S     + P   
Sbjct: 428  TSAPSPA-PKQSFLFGTQNTSPSSPAAPAASSAPPMFKPIFT--APPKSEKEGPTPPGPS 484

Query: 556  TAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPAEILKEGSVLDILKSP 615
                + SSS+L    S++A     V S+     PP        PA   K+ +      +P
Sbjct: 485  VTATAPSSSSLPTTTSTTAPTFQPVFSS---MGPPASVP---LPAPFFKQTTTP--ATAP 536

Query: 616  GFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTD 675
               +P    +A+  +A +P+    P+  S S    GFG +  + SS    T         
Sbjct: 537  TTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTT--------- 587

Query: 676  NKCIACQAAKLSPRDTAKQTGI-ETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQ 734
                       S    A Q  +   P  S  +   A G+ F     P + T    T   Q
Sbjct: 588  -----------STATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQ 636

Query: 735  NKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPI 794
            +   A+      +    +     L  +  + S++  T + S+ +  T  + FG   K P+
Sbjct: 637  SLHTAVPTATSSSAADFSGFGSTLATSAPATSSQP-TLTFSNTSTPTFNIPFGSSAKSPL 695

Query: 795  GSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASS----------SSTVPVSLPSGGSLG 844
             S+  +    +  A +        + PG++ PA +          +S  P + P+     
Sbjct: 696  PSYPGANPQPAFGAAE-------GQPPGAAKPALAPSFGSSFTFGNSAAPAAAPTPAPPS 748

Query: 845  LEKFKKPEGSWDCELCL--VQNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSS 902
            + K                  + A   K  A     P +     G  T +    +A SS 
Sbjct: 749  MIKVVPAYVPTPIHPIFGGATHSAFGLKATASAFGAPASSQPAFGGST-AVFFGAATSSG 807

Query: 903  FKFGVSSSSSGPSQTL---TSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDF 959
            F     ++SSG S ++   T+   F F   GG      S S  IN  + G   S   G F
Sbjct: 808  FGATTQTASSGSSSSVFGSTTPSPFTF---GGSAAPAGSGSFGINVATPG--SSTTTGAF 862

Query: 960  KFGVSSESKPEEVKKDSKNDNFKFGL-SSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSS 1018
             FG             + +  F  GL  + L      TPF F VS+    E K     ++
Sbjct: 863  SFGAGQSG------STATSTPFAGGLGQNALGTTGQSTPFAFNVSS--TTESKPVFGGTA 914

Query: 1019 SAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS-ASVAPF 1063
            +  F        +TPAP   + TS +  SF   +   +    VAPF
Sbjct: 915  TPTFGL------NTPAPG--VGTSGSSLSFGASSAPAQGFVGVAPF 952



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 143/607 (23%), Positives = 226/607 (37%), Gaps = 128/607 (21%)

Query: 930  GGFKIGVSSDSGS--INPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSS 987
            G  K G++S S    +N  S     S   G +  G+ S S+       S       G+S 
Sbjct: 105  GSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYASGIPSSSRNAITSSYSSTR----GISQ 160

Query: 988  -GLSNPVSLTPFQFGVSNLGQEEKK-------EELPKSSSAGFSFGTGVINSTPAPANTI 1039
                N  S +PF    S+  Q  ++       EEL   SS+          STP  A+  
Sbjct: 161  LWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSS----------STPLAADRE 210

Query: 1040 VTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFV 1099
               E  +       +  ++   P +    + K + +P+ +G       E  +LP      
Sbjct: 211  SQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRG-------EQLTLPPPPQ-- 261

Query: 1100 LGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKS-TFSFSMTKP 1158
            LG +       +T+  L   KKA  +         F  + + K + +S S T +  +T+P
Sbjct: 262  LGYS-------ITAEDLDLEKKASLQW--------FNQALEDKSDAASNSVTETPPITQP 306

Query: 1159 SEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSS 1218
            S   +  PA A     A   T+    +  P+   L    +  S P      G   ++T +
Sbjct: 307  SFTFT-LPAAAP----ASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAG--AATTEA 359

Query: 1219 SNPPVATFVF-----GQSSNP--VSSSAFGNTAESST-----SQSLLFSQDSKLATTSST 1266
             +PP    +       QS  P  + S +F +   ++      + S++ + D+K   T   
Sbjct: 360  LSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQA 419

Query: 1267 GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQT-P 1325
             TA  P      ++ +      F FG   TS S+ ++      P+A SA P F    T P
Sbjct: 420  ETATKPQAT---SAPSPAPKQSFLFGTQNTSPSSPAA------PAASSAPPMFKPIFTAP 470

Query: 1326 TFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPV-------FGQQP 1378
               + +G + P P    +  SS++L PT +    PTF  V SS  PP        F +Q 
Sbjct: 471  PKSEKEGPTPPGPSVTATAPSSSSL-PTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQT 529

Query: 1379 SQSAFGSGTT---------------------PNSSS----AFQFG------SSTTNFNFT 1407
            +  A    TT                     P++ S    AF FG      SS +    T
Sbjct: 530  TTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTST 589

Query: 1408 NNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPA---AFTVGSNGKNVF-------SS 1457
              + S  F FGA  ++ AAS  P+    F F + PA     TV +  +++        SS
Sbjct: 590  ATAASQPFLFGAPQAS-AASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLHTAVPTATSS 648

Query: 1458 SGTSFSG 1464
            S   FSG
Sbjct: 649  SAADFSG 655


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 136/666 (20%), Positives = 264/666 (39%), Gaps = 27/666 (4%)

Query: 805  SNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQN 864
            S+++ DN   S  S    SS  + SS +   S  S  S   +     + S   E     +
Sbjct: 647  SSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSD 706

Query: 865  KADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNF 924
             +DS    + +S+   +       D+S+SS +S +S+S     SS SS  S +  S+ + 
Sbjct: 707  SSDSDSSDSSDSSNSNSSDS----DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 762

Query: 925  KFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFG 984
               D        SSDS   +  S     +          SS S       DS + +    
Sbjct: 763  NSSDSSD-----SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817

Query: 985  LSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSEN 1044
              S  S+  S +      SN        +    S +  S  +   NS+ +  ++  ++ +
Sbjct: 818  SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS 877

Query: 1045 KSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTE 1104
             SS +  + E+ ++S +  +  +S++   +   +       N   +S  S++      + 
Sbjct: 878  DSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSS-ESSNSSDNSNSS 936

Query: 1105 EKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESE 1164
            +      +S S      +D+            NS  + D NSS S+ S + +  S+    
Sbjct: 937  DSSNSSDSSDSSDSSNSSDSSNSS-----DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS 991

Query: 1165 QPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVA 1224
              +  +    + +S ++D   +       N+S SS+S+ ++++      S +S S+    
Sbjct: 992  SDSSDS----SDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047

Query: 1225 TFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGAS-SNN 1283
            +     SSN   SS   ++++SS S     S DS  ++ SS  +  +       +S S++
Sbjct: 1048 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSD 1107

Query: 1284 TTTSGFGFGATTTSSSAGSSFVFGTGPSAPS-----ASPAFGANQTPTFGQSQGASQPNP 1338
            ++ S     ++ +S+S+ SS    +  S+ S     +S +  ++ +     S  +S  + 
Sbjct: 1108 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSD 1167

Query: 1339 PGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFG 1398
                S SS ++     S  +  +  + SS S         S S+  S ++ +S S+    
Sbjct: 1168 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1227

Query: 1399 SSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSS 1458
            SS +N   +++S S   +  +NSS  + S+  S S     ++S +    G NG N  S S
Sbjct: 1228 SSDSN-ESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSG-NGNNNGSDS 1285

Query: 1459 GTSFSG 1464
             +   G
Sbjct: 1286 DSDSEG 1291



 Score = 81.6 bits (200), Expect = 5e-15
 Identities = 118/601 (19%), Positives = 234/601 (38%), Gaps = 45/601 (7%)

Query: 863  QNKADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTG 922
            + K+DS+   + +S+     S     D+S S+S+S + SS      SS S  S +  S+ 
Sbjct: 544  KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD 603

Query: 923  NFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFK 982
                          SSDS   +  S+    S    D     SS+S+ +    DSK+D+  
Sbjct: 604  --------------SSDSSDSSDSSDSSDSSDSKSD-----SSKSESDSSDSDSKSDSSD 644

Query: 983  FGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTS 1042
               S    N  S        SN        +   SSS+  S  +   + +   +N+  +S
Sbjct: 645  SNSSDSSDNSDSSD--SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESS 702

Query: 1043 ENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGR 1102
            ++  S +  + ++  +S        S +   +   +       N   +S  S S      
Sbjct: 703  DSSDSSDSDSSDSSDSS-------NSNSSDSDSSNSSDSSDSSNSSDSSDSSDS----SN 751

Query: 1103 TEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKE 1162
            + +      +S S      +D+ +       S  N      ++S  S  S S       +
Sbjct: 752  SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD 811

Query: 1163 SEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPP 1222
            S   + +  +  + +S ++D   +       +NSS SS +  +S G     S+ S S+  
Sbjct: 812  SSDSSDSDSSNSSDSSNSSDSSDS-------SNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864

Query: 1223 VATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSN 1282
                    SS+   SS   ++++SS S     S DS  ++ SS   +         + S+
Sbjct: 865  ------SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS 918

Query: 1283 NTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFG 1342
            N++ S     ++  S+S+ SS    +  S+ S++ +  +N + +   S  +   +     
Sbjct: 919  NSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSD 978

Query: 1343 SISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTT 1402
            S +SS +   + S  +  +  + +SS          S ++  S  + +SS++     S+ 
Sbjct: 979  SSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSD 1038

Query: 1403 NFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSF 1462
            + + +++S S   +  +NSS  + S+  S S     +   +  +  S+  +  +SS +S 
Sbjct: 1039 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSD 1098

Query: 1463 S 1463
            S
Sbjct: 1099 S 1099



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 128/660 (19%), Positives = 254/660 (38%), Gaps = 39/660 (5%)

Query: 805  SNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQN 864
            SN++ D+      S     S  + SS++   S  S  S   +     +   D       +
Sbjct: 574  SNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDS 633

Query: 865  KADSTKCLACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNF 924
                +K  + +S    +       D+S+SS++S +S S     SSSSS  S +  S+   
Sbjct: 634  SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD-- 691

Query: 925  KFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFG 984
                        SSDS + +  S+         D     SS+S        S +D+    
Sbjct: 692  ------------SSDSSNSSESSDS-------SDSSDSDSSDSSDSSNSNSSDSDSSNSS 732

Query: 985  LSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSEN 1044
             SS  SN    +      ++    +  +    S S+  S  +   +S+ +  +   ++ +
Sbjct: 733  DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792

Query: 1045 KSSFNLGTIETKSASVAPFTCKTSEA-KKEEMPATKGGFSFGNVEPASLPSASVFVLGRT 1103
             SS +  + ++ ++S +  +  +S++       ++    S  +   +    +S    G  
Sbjct: 793  DSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSD 852

Query: 1104 EEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKES 1163
             +      +S S      +D+         S  N      ++S  S  S S +  S   S
Sbjct: 853  SDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS 912

Query: 1164 EQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPV 1223
            +    +  +  +++S ++D           +NSS SS++  +S       SS SS++   
Sbjct: 913  DSSDSSNSSDSSESSNSSDN----------SNSSDSSNSSDSSDSSDSSNSSDSSNSSDS 962

Query: 1224 ATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNN 1283
            +       SN   SS   N+++SS S     S DS  ++ SS  +  +       + S+N
Sbjct: 963  SNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSS-----DSSDSSN 1017

Query: 1284 TTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGS 1343
            ++ S     ++ +S S+ SS    +  S+ S+  +  +N + +   S  +S  +     S
Sbjct: 1018 SSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS-SDSSDSSDSSDSSDSS 1076

Query: 1344 ISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTN 1403
             SS ++     S  +  +  + SS S         S S+  S  + NSS +     S+ +
Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS-DSSDSSNSSDSSDSSDSSDS 1135

Query: 1404 FNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463
             + +N+S S   +  ++SS  + S+  S S     +   +  +  S+  +   SS +S S
Sbjct: 1136 SDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1195



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 125/646 (19%), Positives = 244/646 (37%), Gaps = 31/646 (4%)

Query: 764  SESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGS 823
            S+S+++  +S+SS +  +      D       S   S    S+N+ D+   S  S+   S
Sbjct: 687  SDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDS 746

Query: 824  SVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKS 883
            S  ++SS +   S  S  S   +     + S         N +DS    +  S+     S
Sbjct: 747  SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS------SNSSDSND--SSNSSDSSDSS 798

Query: 884  GFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSI 943
                   SS SS+S+ SS      SS SS  S +  S+ +    D      G  SDS + 
Sbjct: 799  NSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNR 858

Query: 944  NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVS 1003
            +  S     S          SS+S       +S + +     S   S+  S +      S
Sbjct: 859  SDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS 918

Query: 1004 NLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPF 1063
            N     +      +S++  S  +   + +   +N+  +S +  S N       ++S +  
Sbjct: 919  NSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSD 978

Query: 1064 TCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKAD 1123
            +  +S++      +     S  +    S  S+       + +      +S S      +D
Sbjct: 979  SSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSD 1038

Query: 1124 NEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQ 1183
            + +          +S  + D + S ++   S +  S   S+    +  +  +++S ++D 
Sbjct: 1039 SSDSS--------DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDS 1090

Query: 1184 GAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNT 1243
              +       ++S SS S+ ++ +      S++S S+    +     SSN   SS    +
Sbjct: 1091 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSES 1150

Query: 1244 AESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSS 1303
            ++SS S     S DS  ++ SS  +            S+N++ S     ++ +S S+ SS
Sbjct: 1151 SDSSDSSDSSDSSDSSDSSDSSDSS-----------DSSNSSDSSDSSDSSDSSDSSDSS 1199

Query: 1304 FVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFG 1363
                +  S+ S+  +  ++ + +   S  +S  N     S SS ++     S  +  +  
Sbjct: 1200 DSSDSSDSSDSSDSSDSSDSSDS-SDSSDSSDSNESSDSSDSSDSS---DSSNSSDSSDS 1255

Query: 1364 TVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNN 1409
            + SS S      +  SQS  G+G    S S      S +N + +++
Sbjct: 1256 SDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301



 Score = 54.7 bits (130), Expect = 7e-07
 Identities = 73/332 (21%), Positives = 144/332 (43%), Gaps = 18/332 (5%)

Query: 1134 SFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFL 1193
            S GN     D+N  KS      +  S+ +S   + ++ +  +  S ++D  ++    S  
Sbjct: 526  SNGNGNNGNDDN-DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSD 584

Query: 1194 NNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLL 1253
            ++SS SS + ++ +      SS SS +   +       S+   S +  + ++SS S S  
Sbjct: 585  SDSSDSSDSDSSDSS----NSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKS 640

Query: 1254 FSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAP 1313
             S DS  + +S    +         ++S+N++ S     ++ +SSS+ SS    +  S+ 
Sbjct: 641  DSSDSNSSDSSDNSDS------SDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSD 694

Query: 1314 S--ASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQP 1371
            S  +S +  ++ +     S  +   N     S SS+++     S  +  +  + SS+S  
Sbjct: 695  SSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSD 754

Query: 1372 PVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPS 1431
                   S S+  S ++ +S S+    SS +N + +N+S S   +  ++SS  + S+  S
Sbjct: 755  SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSN-DSSNSSDSSDSSNSSDSSNSSDSSDSS 813

Query: 1432 GSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463
             S     + S    +  SN  +   SS +S S
Sbjct: 814  DSSDSDSSNS----SDSSNSSDSSDSSNSSDS 841



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 70/334 (20%), Positives = 143/334 (42%), Gaps = 16/334 (4%)

Query: 1137 NSEQTKDE-NSSKSTFSFSMTKPSEKESEQP-AKATFAFGAQTSTTADQGAAKPVFSFLN 1194
            NS+++KD  N S S  +      S  ++    +      G   +  +D G  K   S  +
Sbjct: 494  NSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSD 553

Query: 1195 NSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLF 1254
            +S SS+S+ ++ +       S SSS+   +      SS+  SS +  N+++SS S     
Sbjct: 554  SSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDS-SNSSDSSDSSDSSD 612

Query: 1255 SQDSKLATTSSTGTAVTPFVFGPG-----ASSNNTTTSGFGFGATTTSSSAGSSFVFGTG 1309
            S DS  ++ S + ++ +            +S +N++ S     ++ +S+S+ SS    + 
Sbjct: 613  SSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSS 672

Query: 1310 PSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSS 1369
             S+ S+S +  +N + +   S  ++        S  SS +   + S  +  +  + S+SS
Sbjct: 673  DSSDSSSSSDSSNSSDSSDSSDSSN--------SSESSDSSDSSDSDSSDSSDSSNSNSS 724

Query: 1370 QPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQ 1429
                     S  +  S  + +SS +     S+ + + +N+S S   +  ++SS  + S+ 
Sbjct: 725  DSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 784

Query: 1430 PSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463
             + S     +   +  +  SN  +   SS +S S
Sbjct: 785  SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDS 818



 Score = 39.7 bits (91), Expect = 0.022
 Identities = 46/191 (24%), Positives = 84/191 (43%), Gaps = 10/191 (5%)

Query: 67  SCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVL 126
           S S+D+S+     ++K D    + +  S+ +D     + + SN+ + S  S +S+  +  
Sbjct: 608 SDSSDSSDSSDSSDSKSD----SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN-- 661

Query: 127 TRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSG 186
              S + S  + S   S +     S++S+    SS  S   E  DS+   D D+  ++  
Sbjct: 662 ---SSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDS 718

Query: 187 FSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNS 246
            +S +SD D + S ++S     S  ++ S S S  + +S    + N S     S S  +S
Sbjct: 719 SNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS-SNSSDSSDSSDSSNSSDSSDSSDSSDSS 777

Query: 247 SILKTSQLGDS 257
               +S   DS
Sbjct: 778 DSSNSSDSNDS 788



 Score = 39.7 bits (91), Expect = 0.022
 Identities = 48/191 (25%), Positives = 78/191 (40%), Gaps = 9/191 (4%)

Query: 67   SCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVL 126
            S S+D+SE     +N          +SSN +D   + +   SN+ + S +S +SN  D  
Sbjct: 918  SNSSDSSESSNSSDNSNS------SDSSNSSDSSDSSDS--SNSSDSSNSSDSSNSSDSS 969

Query: 127  TRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSG 186
               S   S  + S   S +     S+ S+    SS  S   +  DS++  D  N S +S 
Sbjct: 970  DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029

Query: 187  FSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNS 246
             SS +SD   +   + S     S ++  S   S  + +S    + + S     S S  +S
Sbjct: 1030 -SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS 1088

Query: 247  SILKTSQLGDS 257
                +S   DS
Sbjct: 1089 DSSNSSDSSDS 1099



 Score = 35.4 bits (80), Expect = 0.41
 Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 15/200 (7%)

Query: 60   NKNEDVCSCSTDTSEVPRWPENKE--DHLVYADEESSNITDGRITPEPAVSNTEEPSTTS 117
            + N    S S+D+S+     ++ +  D    +D +SSN +D         SN+ + S +S
Sbjct: 820  SSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS--------SNSSDSSDSS 871

Query: 118  TASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHD 177
             +SN  D       + S  +    +S       S+ S+    SS  S   +  +S++  D
Sbjct: 872  DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931

Query: 178  DDNISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFG 237
            + N S +S  S  +   D   S N+S     S  +  S S   +++ SS   + N S   
Sbjct: 932  NSNSSDSSNSSDSSDSSD---SSNSSDSSNSSDSSNSSDSSDSNSSDSS--DSSNSSDSS 986

Query: 238  TLSPSLGNSSILKTSQLGDS 257
              S S  +S    +S   DS
Sbjct: 987  DSSDSSDSSDSSDSSNSSDS 1006



 Score = 34.7 bits (78), Expect = 0.70
 Identities = 46/170 (27%), Positives = 77/170 (45%), Gaps = 10/170 (5%)

Query: 89  ADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHC 148
           +D +SSN +D   + +   S++   S +S +S+  D     S +RS  + S   S +   
Sbjct: 816 SDSDSSNSSDSSNSSDS--SDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873

Query: 149 QPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASDKDITVSKNTSLPPLW 208
             S+ S+    S+  S   +  DS++  D D  S+ S  SS +SD     S N+S     
Sbjct: 874 SNSSDSSDSSDSNESSNSSDSSDSSNSSDSD--SSDSSNSSDSSD-----SSNSSDSSES 926

Query: 209 SPEAERSHSL-SQHTATSSKKPAFNLSAFGTLSPSLGNSSILKTSQLGDS 257
           S  ++ S+S  S +++ SS     + S+  + S    NSS    S   DS
Sbjct: 927 SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDS 976



 Score = 33.1 bits (74), Expect = 2.0
 Identities = 41/188 (21%), Positives = 80/188 (42%), Gaps = 4/188 (2%)

Query: 60  NKNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTA 119
           + N    S S+D+S+     ++          +SSN ++   + + + S++ + S +S  
Sbjct: 662 SSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSN- 720

Query: 120 SNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDD 179
           SN  D     S + S  + S   S +     S++S+    SS  S   +  DS+   D  
Sbjct: 721 SNSSD---SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777

Query: 180 NISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTL 239
           + S +S  +  ++  D + S N+S     S  ++ S S    ++ SS     + S+  + 
Sbjct: 778 DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN 837

Query: 240 SPSLGNSS 247
           S    +SS
Sbjct: 838 SSDSSDSS 845



 Score = 32.0 bits (71), Expect = 4.5
 Identities = 42/190 (22%), Positives = 81/190 (42%), Gaps = 6/190 (3%)

Query: 67   SCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPA----VSNTEEPSTTSTASNY 122
            S S+D+S+     ++ +        +SSN +D   + E +     S++ + S +S +S+ 
Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDS 1171

Query: 123  PDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNIS 182
             D  +  S + S  + S   S +     S+ S+    SS  S   +  DS+   D  + S
Sbjct: 1172 SD--SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229

Query: 183  TTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPS 242
             ++  S  +   D + S N+S     S  ++ +   +  + + SK    N +   + S S
Sbjct: 1230 DSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDS 1289

Query: 243  LGNSSILKTS 252
             G+ S   TS
Sbjct: 1290 EGSDSNHSTS 1299



 Score = 31.6 bits (70), Expect = 5.9
 Identities = 43/199 (21%), Positives = 82/199 (41%), Gaps = 7/199 (3%)

Query: 60   NKNEDVCSCSTDTSEVPRWPENKEDHLVYADEESSNITDGRITPEPA-VSNTEEPSTTST 118
            + N    S S+D+S+     ++          +SS+ +D   + + +  S++ + S +S 
Sbjct: 1000 SSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1059

Query: 119  ASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDD 178
            +S+  D  +  S   S  + S   S +     S++S+    SS  S   +  DS+   D 
Sbjct: 1060 SSDSSD--SSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117

Query: 179  DNISTTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGT 238
             + S +S  S  +   D + S N+S     S ++  S   S  + +S    + + S    
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSS----DSSDSSESSDSSDSSDSSDSSDSSDSSDSSD 1173

Query: 239  LSPSLGNSSILKTSQLGDS 257
             S S  +S    +S   DS
Sbjct: 1174 SSDSSNSSDSSDSSDSSDS 1192


>gi|56549643 nucleoporin 98kD isoform 3 [Homo sapiens]
          Length = 937

 Score = 78.2 bits (191), Expect = 6e-14
 Identities = 135/579 (23%), Positives = 210/579 (36%), Gaps = 124/579 (21%)

Query: 900  SSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE-GFKFSKPIGD 958
            + SF       + G   T T   N  FG   G   G S+   S N     G   +KP G 
Sbjct: 3    NKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGG- 61

Query: 959  FKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQE---EKKEELP 1015
              FG SS S+P      S +  F FG S+G +N +      FG ++ G      +     
Sbjct: 62   -LFGTSSFSQPAT----STSTGFGFGTSTGTANTL------FGTASTGTSLFSSQNNAFA 110

Query: 1016 KSSSAGF-SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEE 1074
            ++   GF +FGT                   S+ + G   T + +  PF           
Sbjct: 111  QNKPTGFGNFGT-------------------STSSGGLFGTTNTTSNPF----------- 140

Query: 1075 MPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFS 1134
               +  G  FG   P+S  +A       T  K   P  + ++V    + N   K Q + +
Sbjct: 141  --GSTSGSLFG---PSSFTAAPT----GTTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191

Query: 1135 FGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLN 1194
                E    E      +  +   P  +            GA T+T               
Sbjct: 192  MKEYESKSLEELRLEDYQANRKGPQNQ-----------VGAGTTT--------------- 225

Query: 1195 NSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFG-NTAESSTSQSLL 1253
                  S+PATS+  G+F SST++S      F +GQ+      +AFG +T    T+   L
Sbjct: 226  --GLFGSSPATSSATGLFSSSTTNSG-----FAYGQNK-----TAFGTSTTGFGTNPGGL 273

Query: 1254 FSQDSKLATT-------SSTGTAVTPFVFGPGASSNNTTTSGFG-FGAT----------- 1294
            F Q ++  T+        +T T  T F FG  ++    +T+  G FG T           
Sbjct: 274  FGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGT 333

Query: 1295 TTSSSAGSSFVFGTGPSAPS-------ASPAFGANQTPTFGQSQGASQPNPPGFGSISSS 1347
             T++S G++F  GTG    +        S  FG N+  TFG S  ++       G +  +
Sbjct: 334  ATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGN 393

Query: 1348 TALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFT 1407
                  G+      FG  +++S   +FG +P+    G+G      +A   G ++    F 
Sbjct: 394  KPTLTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASL---FG 450

Query: 1408 NNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446
            NN P      G  +         + + GF   Q+P A T
Sbjct: 451  NNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALT 489



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 72/230 (31%), Positives = 102/230 (44%), Gaps = 28/230 (12%)

Query: 1225 TFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNT 1284
            T +FG  S+P +SSA G  + S+T+    + Q+     TS+TG    P   G     N  
Sbjct: 225  TGLFG--SSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPG--GLFGQQNQQ 280

Query: 1285 TTSGFG--FGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFG 1342
            TTS F   FG  TT+ + G SF    G ++    P+   N    FG +Q +      G  
Sbjct: 281  TTSLFSKPFGQATTTQNTGFSF----GNTSTIGQPS--TNTMGLFGVTQASQPGGLFGTA 334

Query: 1343 SISSSTALFPTGSQPAPPT---FGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGS 1399
            + +S+   F TG+     T   FG V S+    +FG     + FGS TT    SA  FG 
Sbjct: 335  TNTSTGTAFGTGTGLFGQTNTGFGAVGST----LFGNN-KLTTFGSSTT----SAPSFG- 384

Query: 1400 STTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGS 1449
             TT+     N P+   T G N++T       + SG   F   PA  T+G+
Sbjct: 385  -TTSGGLFGNKPT--LTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGT 431



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 132/538 (24%), Positives = 195/538 (36%), Gaps = 114/538 (21%)

Query: 880  GTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGN-FKFGDQGGFK---IG 935
            G   G   F +S+++     +S  K G    +S  SQ  TST   F FG   G      G
Sbjct: 34   GGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFG 93

Query: 936  VSSDSGSI-NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVS 994
             +S   S+ +  +  F  +KP G   FG S+ S               FG ++  SNP  
Sbjct: 94   TASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSS------------GGLFGTTNTTSNPFG 141

Query: 995  LTPFQ-FGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTI 1053
             T    FG S+          P  ++  F+  TG      A  +T ++++++    +   
Sbjct: 142  STSGSLFGPSSF------TAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEY 195

Query: 1054 ETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTS 1113
            E+KS           E + E+  A + G           P   V     T      P TS
Sbjct: 196  ESKSLE---------ELRLEDYQANRKG-----------PQNQVGAGTTTGLFGSSPATS 235

Query: 1114 TSL-VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFA 1172
            ++  +F     N        F++G ++         ST  F  T P     +Q  + T  
Sbjct: 236  SATGLFSSSTTNSG------FAYGQNKTA----FGTSTTGFG-TNPGGLFGQQNQQTTSL 284

Query: 1173 FG---AQTSTTADQGAAKPVFSFLNNSSSSSSTPAT---------SAGGGIFGSSTSSSN 1220
            F     Q +TT + G     FSF N S+    +  T         S  GG+FG++T++S 
Sbjct: 285  FSKPFGQATTTQNTG-----FSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTST 339

Query: 1221 PPV---ATFVFGQSSN---PVSSSAFGN----TAESSTSQSLLFSQDS------KLATTS 1264
                   T +FGQ++     V S+ FGN    T  SST+ +  F   S      K   T 
Sbjct: 340  GTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTL 399

Query: 1265 STGTAVTPFVFGPGASSNNTT-------TSGFGFGATT-TSSSAGSSFVFGT-------- 1308
             T T  + F FG   S N+         T G G GA   T+  AG + +FG         
Sbjct: 400  GTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGP 459

Query: 1309 ---------GPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQP 1357
                     G +  +A+  FGA Q P       AS           +S    P G  P
Sbjct: 460  LGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSP 517



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 93/335 (27%), Positives = 136/335 (40%), Gaps = 52/335 (15%)

Query: 1167 AKATFAFGAQTSTTADQGAA--KPVFSFLNNSSSSSSTPATSAGGGI-FGSSTSSSNP-- 1221
            A  T AFG+  +T    G +  KP   F    +SS S PATS   G  FG+ST ++N   
Sbjct: 36   AFGTSAFGSSNNTGGLFGNSQTKPGGLF---GTSSFSQPATSTSTGFGFGTSTGTANTLF 92

Query: 1222 ---PVATFVFGQSSNPVSSS---AFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVF 1275
                  T +F   +N  + +    FGN   S++S  L  + +    TTS+   + +  +F
Sbjct: 93   GTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTN----TTSNPFGSTSGSLF 148

Query: 1276 GPGASSNNTTTSGFGFG---ATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFG-QSQ 1331
            GP + +   T +   F     T T   AG S    T     +A   + +        +  
Sbjct: 149  GPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDY 208

Query: 1332 GASQPNPPGFGSISSSTALFPTGSQPAPPTF-GTVSSSSQPPVFGQQPSQSAFGS----- 1385
             A++  P       ++T LF  GS PA  +  G  SSS+    F    +++AFG+     
Sbjct: 209  QANRKGPQNQVGAGTTTGLF--GSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGF 266

Query: 1386 GTTP---------NSSSAFQ--FGSST----TNFNFTNNSPSG---VFTFGANSSTPAAS 1427
            GT P          ++S F   FG +T    T F+F N S  G     T G    T A  
Sbjct: 267  GTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQA-- 324

Query: 1428 AQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSF 1462
            +QP G  G   N S    T    G  +F  + T F
Sbjct: 325  SQPGGLFGTATNTSTG--TAFGTGTGLFGQTNTGF 357



 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 80/285 (28%), Positives = 116/285 (40%), Gaps = 49/285 (17%)

Query: 1192 FLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS 1251
            F   S+   +T   +  GG FG+S            FG S+N  +   FGN   S T   
Sbjct: 17   FGTTSTFGQNTGFGTTSGGAFGTS-----------AFGSSNN--TGGLFGN---SQTKPG 60

Query: 1252 LLF--SQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTG 1309
             LF  S  S+ AT++STG     F FG    + NT      FG  +T +S  SS      
Sbjct: 61   GLFGTSSFSQPATSTSTG-----FGFGTSTGTANTL-----FGTASTGTSLFSSQNNAFA 110

Query: 1310 PSAPSASPAFGANQTP--TFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSS 1367
             + P+    FG + +    FG +   S P    FGS S S  LF   S  A PT  T+  
Sbjct: 111  QNKPTGFGNFGTSTSSGGLFGTTNTTSNP----FGSTSGS--LFGPSSFTAAPTGTTIKF 164

Query: 1368 SSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAAS 1427
            +  PP      + +   +G + N S+  Q  ++   +   +     +  + AN   P   
Sbjct: 165  N--PPT----GTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQ 218

Query: 1428 AQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTS--FSGRKIKTA 1470
                 + G  F  SPA     S+   +FSSS T+  F+  + KTA
Sbjct: 219  VGAGTTTGL-FGSSPAT----SSATGLFSSSTTNSGFAYGQNKTA 258



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 51/178 (28%), Positives = 75/178 (42%), Gaps = 38/178 (21%)

Query: 1297 SSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPN-----PPGFGSISSSTALF 1351
            + S G+ F  GTG          G   T TFGQ+ G    +        FGS +++  LF
Sbjct: 3    NKSFGTPFGGGTG----------GFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLF 52

Query: 1352 PTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTT--------N 1403
                      FGT SS SQP       + + FG GT+  +++   FG+++T        N
Sbjct: 53   GNSQTKPGGLFGT-SSFSQPAT----STSTGFGFGTSTGTANTL-FGTASTGTSLFSSQN 106

Query: 1404 FNFTNNSPSGVFTFGANSS------TPAASAQPSGS-GGFPFNQSPAAFTVGSNGKNV 1454
              F  N P+G   FG ++S      T   ++ P GS  G  F   P++FT    G  +
Sbjct: 107  NAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLF--GPSSFTAAPTGTTI 162



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 54/186 (29%), Positives = 76/186 (40%), Gaps = 23/186 (12%)

Query: 1285 TTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSI 1344
            T  G G G   T+S+ G +  FGT       + AFG++     G   G SQ  P G    
Sbjct: 8    TPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNT--GGLFGNSQTKPGGLFGT 65

Query: 1345 SSSTALFPTGSQPAPPT-----FGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGS 1399
            SS        SQPA  T     FGT S+ +   +FG     ++ G+    + ++AF    
Sbjct: 66   SSF-------SQPATSTSTGFGFGT-STGTANTLFG----TASTGTSLFSSQNNAFAQNK 113

Query: 1400 STTNFNF-TNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSN---GKNVF 1455
             T   NF T+ S  G+F     +S P  S   S  G   F  +P   T+  N   G +  
Sbjct: 114  PTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTM 173

Query: 1456 SSSGTS 1461
              +G S
Sbjct: 174  VKAGVS 179



 Score = 44.3 bits (103), Expect = 9e-04
 Identities = 58/231 (25%), Positives = 86/231 (37%), Gaps = 42/231 (18%)

Query: 1266 TGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSF--------------------- 1304
            TG   T   FG       T+   FG  A  +S++ G  F                     
Sbjct: 14   TGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPAT 73

Query: 1305 ----VFGTGPSAPSASPAFGANQTPT---FGQSQGASQPNPPGFGSISSSTA---LFPTG 1354
                 FG G S  +A+  FG   T T     Q+   +Q  P GFG+  +ST+   LF T 
Sbjct: 74   STSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTT 133

Query: 1355 SQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTT-----PNSSSAFQFGSSTTNFNFTNN 1409
            +  + P FG+ S S    +FG   S +A  +GTT     P  +        +TN +  + 
Sbjct: 134  NTTSNP-FGSTSGS----LFGPS-SFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQ 187

Query: 1410 SPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGT 1460
              + +  + + S           +   P NQ  A  T G  G +  +SS T
Sbjct: 188  CITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSAT 238


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 321/1460 (21%), Positives = 515/1460 (35%), Gaps = 224/1460 (15%)

Query: 69   STDTSEVPRW-------PENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASN 121
            STDT+  P         PE+   H      +++ + D   T     ++T   S+T +   
Sbjct: 266  STDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGS--- 322

Query: 122  YPDVLTRPSLHRSHLNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNI 181
             P     P+   +H      E       PS+    P  S   S    +K ST+ H   + 
Sbjct: 323  -PHTTLSPASSTTHEG----EPTTFQSWPSSKDTSPAPSGTTSAF--VKLSTTYHSSPSS 375

Query: 182  STTSGFSSRASDKDITVSKNTSLPPLWSPEAERSHSLSQHTATSS---KKPAFNLSAFGT 238
            + T+ FS  AS   +  S+  S P   SP A  +      +ATS    +  A++ S   T
Sbjct: 376  TPTTHFS--ASSTTLGHSEE-STPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGST 432

Query: 239  LSPSLGNSSILKTSQLGDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSA 298
             +     SS   +    +S  + G TT+  ++     + L +T Y + +          +
Sbjct: 433  QTMHFPESSTT-SGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDS 491

Query: 299  QSYGVTSSTARRILQSLEKMSSPLADAKRIPSI-VSSPLNSPLDRSGIDITDFQAKREKV 357
             +    S  ++    S + M++ +  A   PS+ V     SP+    ++ T       K 
Sbjct: 492  STISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTK- 550

Query: 358  DSQYPPVQRLMTPKPVSIATNRSVYFKPSLTPSG---EFRKTNQRIDNKCSTGYEKNMT- 413
                P +    T    S  +  + +   S+T SG   E   ++ R  +  +T +  + T 
Sbjct: 551  ----PGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTM 606

Query: 414  PGQNREQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLP 473
            PG ++E   S  S P    P    LS G       +  E T F  S+P   E   +P   
Sbjct: 607  PGLSQESTAS-HSSPG---PTDTTLSPG-STTASSLGPEYTTF-HSRPGSTETTLLPDNT 660

Query: 474  KISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVK 533
              S  +  +S+P  + +    TT SP+   + Q  +     + PSS  +       P   
Sbjct: 661  TAS-GLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFH-SWPSSNDT------RPAPP 712

Query: 534  STEANVLPPS--SIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPE 591
            +T +  + PS  S G   S+P   T  +S  S+T   +  S+ +H ++  ST     P  
Sbjct: 713  TTTSAFVEPSTTSHGSPSSIP---TTHISARSTTSGLVEESTTYH-SSPGSTQTMHFPES 768

Query: 592  DC-EGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGI 650
            D   G    +      +   I  +P   S  ++   +  ++      T    SS +S   
Sbjct: 769  DTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTS--- 825

Query: 651  GFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSA 710
            G  E   A  S Q  T  +         +    +  SP  +        P  +    LS 
Sbjct: 826  GRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSE 885

Query: 711  SGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTV-VSESAET 769
              T F                   + P +          P T +  A T +  VSE + T
Sbjct: 886  RSTTF------------------HSSPRS----------PATTLSPASTTSSGVSEESTT 917

Query: 770  MTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSE-----KPGSS 824
                S S   +T T  F D    P  S   +    S  + D   +   +      +P +S
Sbjct: 918  ----SHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTS 973

Query: 825  VPASSSSTVPVSLP-SGGSLGLEK----FKKPEGSWDCELCLVQNKADSTKCLACES-AK 878
             P SS ST   +LP S  + GL +    F     S D  L      +      +  S ++
Sbjct: 974  -PISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSR 1032

Query: 879  PGTK--SGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGV 936
            PG+   + F G  T    S  + +S    G + ++  P  T  S+            +G 
Sbjct: 1033 PGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASS------------LGP 1080

Query: 937  SSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLT 996
             S +    P S       P      G+   S P  V   + +       +   +     T
Sbjct: 1081 ESTTFHSGPGSTETTLL-PDNTTASGLLEASTP--VHSSTGSPRTTLSPAGSTTRQGEST 1137

Query: 997  PFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETK 1056
             FQ   S+      K+ +P   +   +F      S  +P++   T  + SS   G  E  
Sbjct: 1138 TFQSWPSS------KDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEES 1191

Query: 1057 ----SASVAPFTC-----KTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQ 1107
                S+ VAP T       T+    EE  A     S G+ +    P +S    GR+EE +
Sbjct: 1192 TTVHSSPVAPATTPSPARSTTSGLVEESTAYHS--SPGSTQTMHFPESST-ASGRSEESR 1248

Query: 1108 QE-----------PVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMT 1156
                         P T+++LV    + +  P       F  S  T    S +ST S S  
Sbjct: 1249 TSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGR-SEESTASHSSP 1307

Query: 1157 KPSEKESEQPAKATFAFGAQTSTTADQGAAKPVF-----SFLNNSSSSSSTPATSAGGGI 1211
               +     P  A F       TT+ + A    F     S     +S+++TP  SA   I
Sbjct: 1308 ---DTNGITPLPAHF-------TTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTI 1357

Query: 1212 FGSS-------------TSSSNPPVATFVFGQSSN------PVSSSAFGNTAESSTSQSL 1252
              SS             TSSS     T ++ Q+ +      P S++  G + ES+T  S 
Sbjct: 1358 LYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSK 1417

Query: 1253 LFSQDSKLA----TTSSTGTAVTPFVFGPGA-----SSNNTTTSGFGFGATTTSSSAGSS 1303
              S ++ L+    TTSS     T     PG+     S  +TT  G    +TT  SS GS 
Sbjct: 1418 PGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGS- 1476

Query: 1304 FVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFG 1363
                      + + AF  + T +    Q    P+ PGF    + T L        P T  
Sbjct: 1477 ----------TETTAFSHSNTMSIHSQQSTPFPDSPGF----THTVL--------PATLT 1514

Query: 1364 TVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSST 1423
            T     +   F    S  A G+   P  S+A       T F + + SP+    F A+SST
Sbjct: 1515 TTDIGQESTAF--HSSSDATGTTPLPARSTASDLVGEPTTF-YISPSPTYTTLFPASSST 1571

Query: 1424 PAASAQPSGSGGFPFNQSPA 1443
               + + +      F+ SP+
Sbjct: 1572 SGLTEEST-----TFHTSPS 1586



 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 302/1441 (20%), Positives = 491/1441 (34%), Gaps = 232/1441 (16%)

Query: 78   WPENKEDHLVYADEESSNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSH-- 135
            +P +    +   + ++S IT        ++  T  P +T+TA       T  S  RS   
Sbjct: 160  FPSHSATSVFVGEPKTSPITSA------SMETTALPGSTTTAGLSEKSTTFYSSPRSPDR 213

Query: 136  -LNFSMLESPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASDK 194
             L+ +   S  +  + +TS + P    G +      DST+       ST S   S     
Sbjct: 214  TLSPARTTSSGVSEKSTTSHSRP----GPTHTIAFPDSTTMPGVSQESTAS--HSIPGST 267

Query: 195  DITVSKNTSLPPLWSPEAERSHSLSQHTATSSKKPAFNLSAFGTLSPSLGNSSILKTSQL 254
            D T+S  T+ P    PE+   HS   +T T+             L  +   S +L+ S  
Sbjct: 268  DTTLSPGTTTPSSLGPESTTFHSSPGYTKTTR------------LPDNTTTSGLLEASTP 315

Query: 255  GDSPFYPGKTTYGGAAAAVRQSKLRNTPYQAPVRRQMKAKQLSAQSYGVTSSTARRILQS 314
              S      TT   A++   + +   T +Q+       +K  S    G TS         
Sbjct: 316  VHSSTGSPHTTLSPASSTTHEGE--PTTFQS----WPSSKDTSPAPSGTTS--------- 360

Query: 315  LEKMSSPLADAKRIPSIVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVS 374
                    A  K   +  SSP ++P        T      E       PV    TP P  
Sbjct: 361  --------AFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPAR 412

Query: 375  IATN----------------RSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNR 418
             AT+                ++++F  S T SG    + +      ST + K+ TP    
Sbjct: 413  SATSGHVEESTAYHRSPGSTQTMHFPESSTTSGH---SEESATFHGSTTHTKSSTPSTTA 469

Query: 419  EQRESGFSYPNFSLPAANGLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLP 478
                + +     S    +   S    G    R E ++   S P   + M   VLP  S P
Sbjct: 470  ALAHTSYHSSLGSTETTHFRDSSTISG----RSEESKASHSSP---DAMATTVLPAGSTP 522

Query: 479  ------ITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIV 532
                   T S + + +  +  +  S+  P  S ++ T      SP +T  P    SS + 
Sbjct: 523  SVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVS 582

Query: 533  KSTEANVLPPSSIGFTFSVPVAKT-----AELSGSSSTLEPIISSSAHHVTTVNSTNCKK 587
            + +  +   P S   T + P + T      E + S S+  P  ++ +   TT +S   + 
Sbjct: 583  EESTTSHSRPGST-HTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEY 641

Query: 588  TP----PEDCEGPFRPAEILKEG------SVLDILKSPGFASPKIDSVAAQPTATSPVVY 637
            T     P   E    P      G       V    +SP        S   Q  +T+   +
Sbjct: 642  TTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSW 701

Query: 638  -----TRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTA 692
                 TRPA  + +S+ +    +     S    T +     T            SP  T 
Sbjct: 702  PSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQ 761

Query: 693  KQTGIETPNKSGK---TTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPK 749
                 E+   SG+   +T S S T         I +    T  +  +P +          
Sbjct: 762  TMHFPESDTTSGRGEESTTSHSST------THTISSAPSTTSALVEEPTSYH------SS 809

Query: 750  PGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAE 809
            PG+        +  +      + +S S    TGT+    +    +   E +   +S+ + 
Sbjct: 810  PGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSM 869

Query: 810  DNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADST 869
            +   +   +  PG     S  ST   S P   +  L            E     ++  ST
Sbjct: 870  ETTALPGSTTTPG----LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGST 925

Query: 870  KCLACESAKPGTKSGFKGFDTSSSSSNS--------AASSSFKFG---VSSSSSGPSQTL 918
               A   +   T  G     T+S SS          A++++   G    S  SSG ++T 
Sbjct: 926  HTTAFPDST--TTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETT 983

Query: 919  TSTGNFKFGDQGGFKIGVSSDSGSI--NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDS 976
               G+           G+S  S +   +P S     S P      GVS ES     +  S
Sbjct: 984  ALPGSTT-------TAGLSEKSTTFYSSPRSPDTTLS-PASTTSSGVSEESTTSHSRPGS 1035

Query: 977  KNDNFKFGL--------------SSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGF 1022
             +     G               SS  S   +L+P     S+LG E          S  F
Sbjct: 1036 THTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPE----------STTF 1085

Query: 1023 SFGTGVINSTPAPANTIVTSENKSS----FNLGTIETKSASVAPFTCKTSE--------A 1070
              G G   +T  P NT  +   ++S     + G+  T + S A  T +  E        +
Sbjct: 1086 HSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRT-TLSPAGSTTRQGESTTFQSWPS 1144

Query: 1071 KKEEMPA---TKGGF----SFGNVEPASLP----SASVFVLGRTEEK---QQEPV----- 1111
             K+ MPA   T   F    +  +  P+S+P    SAS    GR+EE       PV     
Sbjct: 1145 SKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATT 1204

Query: 1112 ------TSTSLVFGKKADNEEPKCQPVFSF-------GNSEQTKDENSS--------KST 1150
                  T++ LV    A +  P       F       G SE+++  +SS         ST
Sbjct: 1205 PSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPST 1264

Query: 1151 FSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG 1210
             S  + +P+   S   + AT  F  ++STT+ +           +++  +  PA     G
Sbjct: 1265 TSALVEEPTSYHSSPGSIATTHF-PESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSG 1323

Query: 1211 IFGSSTSSSNPPVATFVFGQSSNPVSSSAF--GNTAESSTSQSLLFSQDSKLATTSSTGT 1268
                ST+    P      G     ++S+A   G +A+S+   S   S D  L+  S T +
Sbjct: 1324 RIAESTTFYISP------GSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSS 1377

Query: 1269 AVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFG 1328
            +++       + + +T T+ F   +TTTS  +  S  F + P +   + + G+  T +F 
Sbjct: 1378 SISGEPTSLYSQAESTHTTAFP-ASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFA 1436

Query: 1329 QSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTT 1388
            Q        P    S  S  +    G      TF +   S++   F    + S     +T
Sbjct: 1437 QEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQST 1496

Query: 1389 P 1389
            P
Sbjct: 1497 P 1497



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 113/449 (25%), Positives = 167/449 (37%), Gaps = 93/449 (20%)

Query: 1017 SSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMP 1076
            S+ +GFS  TG   +T    NT   S   SS    T      SV   T  T+  K     
Sbjct: 77   STFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTA-TKHFLDS 135

Query: 1077 ATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFG 1136
            +T  G S  +    S P A+   L  +        ++TS+  G      EPK  P+    
Sbjct: 136  STNSGHSEESTVSHSGPGATGTTLFPSH-------SATSVFVG------EPKTSPI---- 178

Query: 1137 NSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNS 1196
                               T  S + +  P   T A  ++ STT         F     S
Sbjct: 179  -------------------TSASMETTALPGSTTTAGLSEKSTT---------FYSSPRS 210

Query: 1197 SSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQ 1256
               + +PA +   G+   ST+S + P  T      + P S++  G + ES+ S S+  S 
Sbjct: 211  PDRTLSPARTTSSGVSEKSTTSHSRPGPTHTI---AFPDSTTMPGVSQESTASHSIPGST 267

Query: 1257 DSKLA----TTSSTGTAVTPFVFGPGASS-----NNTTTSGFGFGATTTSSSAGSSF--- 1304
            D+ L+    T SS G   T F   PG +      +NTTTSG    +T   SS GS     
Sbjct: 268  DTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTL 327

Query: 1305 -------------VFGTGPSAPSASPAFGANQTPTFGQSQGA--SQPNPPGFGSISSSTA 1349
                          F + PS+   SPA  +  T  F +      S P+       S+S+ 
Sbjct: 328  SPASSTTHEGEPTTFQSWPSSKDTSPA-PSGTTSAFVKLSTTYHSSPSSTPTTHFSASST 386

Query: 1350 LFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNN 1409
                  +  P     V++++ PP     P++SA  SG    S++  +   ST   +F  +
Sbjct: 387  TLGHSEESTPVHSSPVATATTPP-----PARSA-TSGHVEESTAYHRSPGSTQTMHFPES 440

Query: 1410 S-------PSGVF---TFGANSSTPAASA 1428
            S        S  F   T    SSTP+ +A
Sbjct: 441  STTSGHSEESATFHGSTTHTKSSTPSTTA 469



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 224/1061 (21%), Positives = 370/1061 (34%), Gaps = 156/1061 (14%)

Query: 459  SKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTS-- 516
            + P+    ME   LP  +     S   T  +SSP     + SP  ++ +  ++   TS  
Sbjct: 175  TSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHS 234

Query: 517  ----------PSSTGSPMFKFSSP----IVKSTEANVLP----PSSIG-----FTFSVPV 553
                      P ST  P     S     I  ST+  + P    PSS+G     F  S   
Sbjct: 235  RPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGY 294

Query: 554  AKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFRPAEILKEGSVLDILK 613
             KT  L  +++T   + +S+  H +T  S +   +P         P       S  D   
Sbjct: 295  TKTTRLPDNTTTSGLLEASTPVHSST-GSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSP 353

Query: 614  SPG---FASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQ 670
            +P     A  K+ +      +++P  +      S SS+ +G  E      S    T    
Sbjct: 354  APSGTTSAFVKLSTTYHSSPSSTPTTHF-----SASSTTLGHSEESTPVHSSPVATATTP 408

Query: 671  ---NKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWD 727
                  T        A   SP  T      E+   SG +  SA+  G     K    +  
Sbjct: 409  PPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTK---SSTP 465

Query: 728  CDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVT------T 781
              T  + +        + ET    T  + + T++  SE ++   +S  +   T      T
Sbjct: 466  STTAALAHTSYHSSLGSTET----THFRDSSTISGRSEESKASHSSPDAMATTVLPAGST 521

Query: 782  GTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGS--SVPASSSST-VPVSLP 838
             ++  GD    PI S       +  +         +SEK  +  S P S  +T +P S+ 
Sbjct: 522  PSVLVGDSTPSPISSGSMETTALPGSTTKPG----LSEKSTTFYSSPRSPDTTHLPASMT 577

Query: 839  SGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTK--SGFKGFDTSSSSSN 896
            S G                         +ST       ++PG+   + F G  T    S 
Sbjct: 578  SSGV----------------------SEESTT----SHSRPGSTHTTAFPGSTTMPGLSQ 611

Query: 897  SAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSKPI 956
             + +S        SS GP+ T  S G+      G       S  GS            P 
Sbjct: 612  ESTASH-------SSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTL------LPD 658

Query: 957  GDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPK 1016
                 G+   S P  V   +++ +     +   +     T F    S+    + +   P 
Sbjct: 659  NTTASGLLEASMP--VHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSS---NDTRPAPPT 713

Query: 1017 SSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMP 1076
            ++SA     T    S  +P++   T  +  S   G +E  +      T  +S    + M 
Sbjct: 714  TTSAFVEPST---TSHGSPSSIPTTHISARSTTSGLVEEST------TYHSSPGSTQTMH 764

Query: 1077 ATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSF- 1135
              +   + G  E ++   +S      T      P T+++LV    + +  P       F 
Sbjct: 765  FPESDTTSGRGEESTTSHSST-----THTISSAPSTTSALVEEPTSYHSSPGSTATTHFP 819

Query: 1136 ------GNSEQTKDENSS-----------KSTFSFSMTKPSEKESEQPAKATFAFGAQTS 1178
                  G SE++   +SS           +ST S  + + +       +  T A    T 
Sbjct: 820  DSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGST- 878

Query: 1179 TTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSS 1238
            TT         F     S +++ +PA++   G+   ST+S + P +T     ++ P S++
Sbjct: 879  TTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHT---TAFPDSTT 935

Query: 1239 AFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSS 1298
              G +  S+TS S   S D+ L   S+T   V      P  SS +T T+    G+TTT+ 
Sbjct: 936  TPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSP-ISSGSTETTALP-GSTTTAG 993

Query: 1299 SAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFP-TGSQP 1357
             +  S  F + P +P  + +  A+ T +    +  +  + PG    S+ T  FP + + P
Sbjct: 994  LSEKSTTFYSSPRSPDTTLS-PASTTSSGVSEESTTSHSRPG----STHTTAFPGSTTMP 1048

Query: 1358 APPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQF-GSSTTNFNFTNNSPSGVFT 1416
                  T S SS          +S   S   P S++     GS+ T     N + SG+  
Sbjct: 1049 GVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLL- 1107

Query: 1417 FGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457
                +STP  S+    +G      SPA  T        F S
Sbjct: 1108 ---EASTPVHSS----TGSPRTTLSPAGSTTRQGESTTFQS 1141



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 133/623 (21%), Positives = 234/623 (37%), Gaps = 61/623 (9%)

Query: 877  AKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGV 936
            A  GT S F    T+  SS S+  ++  F  SS++ G S+  T   +             
Sbjct: 354  APSGTTSAFVKLSTTYHSSPSSTPTTH-FSASSTTLGHSEESTPVHSSPVATATTPPPAR 412

Query: 937  SSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLT 996
            S+ SG +   +   +         F  SS +     +  + + +     SS  S   +L 
Sbjct: 413  SATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALA 472

Query: 997  PFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTP-APANTIVTSENKSSFNLGTIET 1055
               +  S+LG  E       S+ +G S  +   +S+P A A T++ + +  S  +G    
Sbjct: 473  HTSYH-SSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVG---- 527

Query: 1056 KSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS 1115
              ++ +P +  + E        TK G S  +    S P        R+ +    P + TS
Sbjct: 528  -DSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSP--------RSPDTTHLPASMTS 578

Query: 1116 LVFGKKA--DNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAF 1173
                +++   +  P      +F  S  T    S +ST S S   P++      +    + 
Sbjct: 579  SGVSEESTTSHSRPGSTHTTAFPGST-TMPGLSQESTASHSSPGPTDTTLSPGSTTASSL 637

Query: 1174 GAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSN 1233
            G + +T   +  +       +N+++S    A+        S  ++ +P  +T   G+S+ 
Sbjct: 638  GPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTT 697

Query: 1234 --------------PVSSSAF--GNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGP 1277
                          P ++SAF   +T    +  S+  +  S  +TTS      T +   P
Sbjct: 698  FHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSP 757

Query: 1278 GASSN-----NTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSA----------SPAFGAN 1322
            G++       + TTSG G  +TT+ SS  ++    + PS  SA          SP  G+ 
Sbjct: 758  GSTQTMHFPESDTTSGRGEESTTSHSS--TTHTISSAPSTTSALVEEPTSYHSSP--GST 813

Query: 1323 QTPTFGQSQGASQPNPPGFGSISSSTALFPTGS--QPAPPTFGTV--SSSSQPPVFGQQP 1378
             T  F  S   S  +     S SS  A   TG+   PA  T   +   S++ P   G   
Sbjct: 814  ATTHFPDSSTTSGRSEESIASHSSQDA---TGTIVLPARSTNSVLLGESTTSPISSGSME 870

Query: 1379 SQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPF 1438
            + +  GS TTP  S       S+     T  SP+   + G +  +  + ++P  +    F
Sbjct: 871  TTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAF 930

Query: 1439 NQSPAAFTVGSNGKNVFSSSGTS 1461
              S     +  +     SS G++
Sbjct: 931  PDSTTTPGLSRHSTTSHSSPGST 953



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 78/288 (27%), Positives = 124/288 (43%), Gaps = 42/288 (14%)

Query: 1191 SFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFV-FGQSSNPVS-SSAFGNTAESST 1248
            +F   S  + ST  TS GG    +ST SS+ P  TF  +G S   ++ S+A  +  +SST
Sbjct: 78   TFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSST 137

Query: 1249 SQSLLFSQDSKLATT--SSTGTAVTP-------FVFGPGAS---SNNTTTSGFGFGATTT 1296
            +     S++S ++ +   +TGT + P       FV  P  S   S +  T+    G+TTT
Sbjct: 138  NSG--HSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALP-GSTTT 194

Query: 1297 SSSAGSSFVFGTGPSAP--SASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTG 1354
            +  +  S  F + P +P  + SPA   +   +   +   S+P P       + T  FP  
Sbjct: 195  AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGP-------THTIAFPDS 247

Query: 1355 SQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNS----SSAFQFGSSTTNFNFTNNS 1410
            +     +  + +S S P   G   +  + G+ TTP+S    S+ F    S+  +  T   
Sbjct: 248  TTMPGVSQESTASHSIP---GSTDTTLSPGT-TTPSSLGPESTTFH---SSPGYTKTTRL 300

Query: 1411 PSGVFTFG-ANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSS 1457
            P    T G   +STP  S+    +G      SPA+ T        F S
Sbjct: 301  PDNTTTSGLLEASTPVHSS----TGSPHTTLSPASSTTHEGEPTTFQS 344


>gi|24497609 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 74.7 bits (182), Expect = 6e-13
 Identities = 83/278 (29%), Positives = 119/278 (42%), Gaps = 37/278 (13%)

Query: 1197 SSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQS----SNPVSSSAFGNTAESSTSQSL 1252
            S ++ TPAT   G  FG++T +S     +   G S    SN  ++ A  N +      S 
Sbjct: 61   SLATQTPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSN 120

Query: 1253 LFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTG--- 1309
            L +  S    TSS GTA T FVFGP  +S    T+  GF  T  S++  S F  G+    
Sbjct: 121  LTNAISS-TVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNS 179

Query: 1310 --PSAPSASPAFGANQTPTFGQSQGASQPNPP--------GFGSISSSTALFPTGSQPAP 1359
              P+AP+  P   A    T   + GA+QP  P           S+ +S A  PT S    
Sbjct: 180  AQPTAPATLPFTPATPAAT---TAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTG 236

Query: 1360 PTFGTVSSSSQPPVFGQQ------PSQSAFGSGTTPNSSSA---FQFGSSTTNF--NFTN 1408
             +  T  +++  P  G Q      P  ++  S TT  +++A       SSTT F  N   
Sbjct: 237  LSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKP 296

Query: 1409 NSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446
             +P+G+      S+T AA   P G G      + +A T
Sbjct: 297  LAPAGI-----PSNTAAAVTAPPGPGAAAGAAASSAMT 329



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 78/289 (26%), Positives = 117/289 (40%), Gaps = 52/289 (17%)

Query: 1208 GGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTG 1267
            GG  FG++ +++  P   F F  S     +        +ST  + LFS  ++   T +TG
Sbjct: 14   GGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTG 73

Query: 1268 ---------TAVTPFVFGPGAS----SNNTTT------SGFGFGAT--------TTSSSA 1300
                     +  T F  G GAS    SN   T      SGFG G++        T +SS 
Sbjct: 74   FTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQ 133

Query: 1301 GSS---FVFGTGPSAPSASPAFGANQTPTFGQS-QGASQPNPPGFGSISSSTALFPTGSQ 1356
            G++   FVFG  PS  S +PA     T + G S  G S   P GF   S+  +  PT   
Sbjct: 134  GTAPTGFVFG--PSTTSVAPA-----TTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPA 186

Query: 1357 PAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFT 1416
              P T  T ++++        P+ +A  + T P+      F S  T       +P+   T
Sbjct: 187  TLPFTPATPAATTAGATQPAAPTPTATITSTGPS-----LFASIAT-------APTSSAT 234

Query: 1417 FGANSSTP--AASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463
             G +  TP   A A  +G+ GF      AA    +      +++ T+ S
Sbjct: 235  TGLSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTS 283



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 64/206 (31%), Positives = 83/206 (40%), Gaps = 34/206 (16%)

Query: 1266 TGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSF--VFGTGPSAPSASPAFGANQ 1323
            TG     F FG   ++  T  +GF F   +TS + G +F   F    S PS      A Q
Sbjct: 9    TGAPTGGFTFGTAKTATTTPATGFSF---STSGTGGFNFGAPFQPATSTPSTGLFSLATQ 65

Query: 1324 TP-------TFGQSQGASQPNPPGFGSISSSTALFPTGSQPA---PPTFGTVSSSSQPPV 1373
            TP       TFG +  AS       G  +S   L  T + PA   P  FG  SS+    +
Sbjct: 66   TPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAI 125

Query: 1374 FGQQPSQSAFGSGTTPNSSSAFQFGSSTTN---------FNFTNNSPSGVFTFGANSSTP 1424
                 S      GT P   + F FG STT+         F+FT  S +     G N  + 
Sbjct: 126  ----SSTVTSSQGTAP---TGFVFGPSTTSVAPATTSGGFSFTGGSTAQ--PSGFNIGSA 176

Query: 1425 AASAQPSGSGGFPFN-QSPAAFTVGS 1449
              SAQP+     PF   +PAA T G+
Sbjct: 177  GNSAQPTAPATLPFTPATPAATTAGA 202



 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 51/188 (27%), Positives = 76/188 (40%), Gaps = 37/188 (19%)

Query: 1287 SGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISS 1346
            SGF FG T    +    F FGT  +A +         TP  G S   S      FG+   
Sbjct: 2    SGFNFGGT---GAPTGGFTFGTAKTATT---------TPATGFSFSTSGTGGFNFGA--- 46

Query: 1347 STALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNF 1406
                 P     + P+ G  S ++Q P    Q +   FG+ T  +  + F  G   +  N 
Sbjct: 47   -----PFQPATSTPSTGLFSLATQTP--ATQTTGFTFGTATLASGGTGFSLGIGASKLNL 99

Query: 1407 TNN-------SPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNV---FS 1456
            +N        +PSG F  G+++ T A S+  + S G     +P  F  G +  +V    +
Sbjct: 100  SNTAATPAMANPSG-FGLGSSNLTNAISSTVTSSQG----TAPTGFVFGPSTTSVAPATT 154

Query: 1457 SSGTSFSG 1464
            S G SF+G
Sbjct: 155  SGGFSFTG 162



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 86/378 (22%), Positives = 129/378 (34%), Gaps = 85/378 (22%)

Query: 949  GFKFS---KPIGDFKFGVSSESKPEEVK----KDSKNDNFKFGL---------SSGLSNP 992
            GF F     P G F FG +  +            S    F FG          S+GL + 
Sbjct: 3    GFNFGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSL 62

Query: 993  VSLTP------FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKS 1046
             + TP      F FG + L           S   GFS G G      +         N S
Sbjct: 63   ATQTPATQTTGFTFGTATLA----------SGGTGFSLGIGASKLNLSNTAATPAMANPS 112

Query: 1047 SFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFG----NVEPASLPSASVFVLGR 1102
             F LG+    +A  +  T     A          GF FG    +V PA+      F  G 
Sbjct: 113  GFGLGSSNLTNAISSTVTSSQGTAPT--------GFVFGPSTTSVAPATTSGGFSFTGGS 164

Query: 1103 TEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKE 1162
            T +                     P    + S GNS Q     ++ +T  F+   P+   
Sbjct: 165  TAQ---------------------PSGFNIGSAGNSAQP----TAPATLPFTPATPAATT 199

Query: 1163 S--EQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSST-------PATSAGGGIFG 1213
            +   QPA  T      T+T    G +  +F+ +  + +SS+T       P T+AG    G
Sbjct: 200  AGATQPAAPT-----PTATITSTGPS--LFASIATAPTSSATTGLSLCTPVTTAGAPTAG 252

Query: 1214 SSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPF 1273
            +   S   P A      +++  +++    T+ SST+   L  +    A   S   A    
Sbjct: 253  TQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKPLAPAGIPSNTAAAVTA 312

Query: 1274 VFGPGASSNNTTTSGFGF 1291
              GPGA++    +S   +
Sbjct: 313  PPGPGAAAGAAASSAMTY 330



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 74/345 (21%), Positives = 131/345 (37%), Gaps = 69/345 (20%)

Query: 878  KPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS 937
            +P T +   G  + ++ + +  ++ F FG ++ +SG +               GF +G+ 
Sbjct: 49   QPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGT---------------GFSLGIG 93

Query: 938  SDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTP 997
            +   +++  +     + P G   FG+ S              N    +SS +++     P
Sbjct: 94   ASKLNLSNTAATPAMANPSG---FGLGS-------------SNLTNAISSTVTSSQGTAP 137

Query: 998  --FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIET 1055
              F FG S           P ++S GFSF  G   ST  P          S FN+G+   
Sbjct: 138  TGFVFGPST------TSVAPATTSGGFSFTGG---STAQP----------SGFNIGSAGN 178

Query: 1056 KSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPAS-LPSASVFVLGRTEEKQQEPVTST 1114
             +   AP T   +       PAT    + G  +PA+  P+A++   G +         ++
Sbjct: 179  SAQPTAPATLPFT-------PATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTS 231

Query: 1115 SLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFG 1174
            S   G         C PV + G         S K+  + S T  +   +   A AT    
Sbjct: 232  SATTGLSL------CTPVTTAGAPTAGTQGFSLKAPGAASGTSTT---TSTAATATATTT 282

Query: 1175 AQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSS 1219
            + +STT      KP+      S+++++  A    G   G++ SS+
Sbjct: 283  SSSSTTGFALNLKPLAPAGIPSNTAAAVTAPPGPGAAAGAAASSA 327



 Score = 31.2 bits (69), Expect = 7.7
 Identities = 66/299 (22%), Positives = 107/299 (35%), Gaps = 33/299 (11%)

Query: 369 TPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYP 428
           T K  +        F  S T    F    Q   +  STG     T  Q    + +GF++ 
Sbjct: 20  TAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLAT--QTPATQTTGFTFG 77

Query: 429 NFSLPAAN-GLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSS--SLP 485
             +L +   G S G+G     +         + P         +   IS  +TSS  + P
Sbjct: 78  TATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQGTAP 137

Query: 486 TFNFSSPEITTSSPSPINS-------SQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEAN 538
           T     P  T+ +P+  +        S A  +   + S  ++  P    + P   +T A 
Sbjct: 138 TGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPA- 196

Query: 539 VLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598
               ++ G T       TA ++ +  +L   I+++     T   + C  TP      P  
Sbjct: 197 ---ATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLC--TPVTTAGAP-- 249

Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLK 657
                  G+    LK+PG AS    + +   TAT        A ++ SSS  GF  +LK
Sbjct: 250 -----TAGTQGFSLKAPGAASGTSTTTSTAATAT--------ATTTSSSSTTGFALNLK 295


>gi|24497607 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 74.7 bits (182), Expect = 6e-13
 Identities = 83/278 (29%), Positives = 119/278 (42%), Gaps = 37/278 (13%)

Query: 1197 SSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQS----SNPVSSSAFGNTAESSTSQSL 1252
            S ++ TPAT   G  FG++T +S     +   G S    SN  ++ A  N +      S 
Sbjct: 61   SLATQTPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSN 120

Query: 1253 LFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTG--- 1309
            L +  S    TSS GTA T FVFGP  +S    T+  GF  T  S++  S F  G+    
Sbjct: 121  LTNAISS-TVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNS 179

Query: 1310 --PSAPSASPAFGANQTPTFGQSQGASQPNPP--------GFGSISSSTALFPTGSQPAP 1359
              P+AP+  P   A    T   + GA+QP  P           S+ +S A  PT S    
Sbjct: 180  AQPTAPATLPFTPATPAAT---TAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTG 236

Query: 1360 PTFGTVSSSSQPPVFGQQ------PSQSAFGSGTTPNSSSA---FQFGSSTTNF--NFTN 1408
             +  T  +++  P  G Q      P  ++  S TT  +++A       SSTT F  N   
Sbjct: 237  LSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKP 296

Query: 1409 NSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446
             +P+G+      S+T AA   P G G      + +A T
Sbjct: 297  LAPAGI-----PSNTAAAVTAPPGPGAAAGAAASSAMT 329



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 78/289 (26%), Positives = 117/289 (40%), Gaps = 52/289 (17%)

Query: 1208 GGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTG 1267
            GG  FG++ +++  P   F F  S     +        +ST  + LFS  ++   T +TG
Sbjct: 14   GGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTG 73

Query: 1268 ---------TAVTPFVFGPGAS----SNNTTT------SGFGFGAT--------TTSSSA 1300
                     +  T F  G GAS    SN   T      SGFG G++        T +SS 
Sbjct: 74   FTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQ 133

Query: 1301 GSS---FVFGTGPSAPSASPAFGANQTPTFGQS-QGASQPNPPGFGSISSSTALFPTGSQ 1356
            G++   FVFG  PS  S +PA     T + G S  G S   P GF   S+  +  PT   
Sbjct: 134  GTAPTGFVFG--PSTTSVAPA-----TTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPA 186

Query: 1357 PAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFT 1416
              P T  T ++++        P+ +A  + T P+      F S  T       +P+   T
Sbjct: 187  TLPFTPATPAATTAGATQPAAPTPTATITSTGPS-----LFASIAT-------APTSSAT 234

Query: 1417 FGANSSTP--AASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463
             G +  TP   A A  +G+ GF      AA    +      +++ T+ S
Sbjct: 235  TGLSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTS 283



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 64/206 (31%), Positives = 83/206 (40%), Gaps = 34/206 (16%)

Query: 1266 TGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSF--VFGTGPSAPSASPAFGANQ 1323
            TG     F FG   ++  T  +GF F   +TS + G +F   F    S PS      A Q
Sbjct: 9    TGAPTGGFTFGTAKTATTTPATGFSF---STSGTGGFNFGAPFQPATSTPSTGLFSLATQ 65

Query: 1324 TP-------TFGQSQGASQPNPPGFGSISSSTALFPTGSQPA---PPTFGTVSSSSQPPV 1373
            TP       TFG +  AS       G  +S   L  T + PA   P  FG  SS+    +
Sbjct: 66   TPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAI 125

Query: 1374 FGQQPSQSAFGSGTTPNSSSAFQFGSSTTN---------FNFTNNSPSGVFTFGANSSTP 1424
                 S      GT P   + F FG STT+         F+FT  S +     G N  + 
Sbjct: 126  ----SSTVTSSQGTAP---TGFVFGPSTTSVAPATTSGGFSFTGGSTAQ--PSGFNIGSA 176

Query: 1425 AASAQPSGSGGFPFN-QSPAAFTVGS 1449
              SAQP+     PF   +PAA T G+
Sbjct: 177  GNSAQPTAPATLPFTPATPAATTAGA 202



 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 51/188 (27%), Positives = 76/188 (40%), Gaps = 37/188 (19%)

Query: 1287 SGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISS 1346
            SGF FG T    +    F FGT  +A +         TP  G S   S      FG+   
Sbjct: 2    SGFNFGGT---GAPTGGFTFGTAKTATT---------TPATGFSFSTSGTGGFNFGA--- 46

Query: 1347 STALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNF 1406
                 P     + P+ G  S ++Q P    Q +   FG+ T  +  + F  G   +  N 
Sbjct: 47   -----PFQPATSTPSTGLFSLATQTP--ATQTTGFTFGTATLASGGTGFSLGIGASKLNL 99

Query: 1407 TNN-------SPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNV---FS 1456
            +N        +PSG F  G+++ T A S+  + S G     +P  F  G +  +V    +
Sbjct: 100  SNTAATPAMANPSG-FGLGSSNLTNAISSTVTSSQG----TAPTGFVFGPSTTSVAPATT 154

Query: 1457 SSGTSFSG 1464
            S G SF+G
Sbjct: 155  SGGFSFTG 162



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 86/378 (22%), Positives = 129/378 (34%), Gaps = 85/378 (22%)

Query: 949  GFKFS---KPIGDFKFGVSSESKPEEVK----KDSKNDNFKFGL---------SSGLSNP 992
            GF F     P G F FG +  +            S    F FG          S+GL + 
Sbjct: 3    GFNFGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSL 62

Query: 993  VSLTP------FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKS 1046
             + TP      F FG + L           S   GFS G G      +         N S
Sbjct: 63   ATQTPATQTTGFTFGTATLA----------SGGTGFSLGIGASKLNLSNTAATPAMANPS 112

Query: 1047 SFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFG----NVEPASLPSASVFVLGR 1102
             F LG+    +A  +  T     A          GF FG    +V PA+      F  G 
Sbjct: 113  GFGLGSSNLTNAISSTVTSSQGTAPT--------GFVFGPSTTSVAPATTSGGFSFTGGS 164

Query: 1103 TEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKE 1162
            T +                     P    + S GNS Q     ++ +T  F+   P+   
Sbjct: 165  TAQ---------------------PSGFNIGSAGNSAQP----TAPATLPFTPATPAATT 199

Query: 1163 S--EQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSST-------PATSAGGGIFG 1213
            +   QPA  T      T+T    G +  +F+ +  + +SS+T       P T+AG    G
Sbjct: 200  AGATQPAAPT-----PTATITSTGPS--LFASIATAPTSSATTGLSLCTPVTTAGAPTAG 252

Query: 1214 SSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPF 1273
            +   S   P A      +++  +++    T+ SST+   L  +    A   S   A    
Sbjct: 253  TQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKPLAPAGIPSNTAAAVTA 312

Query: 1274 VFGPGASSNNTTTSGFGF 1291
              GPGA++    +S   +
Sbjct: 313  PPGPGAAAGAAASSAMTY 330



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 74/345 (21%), Positives = 131/345 (37%), Gaps = 69/345 (20%)

Query: 878  KPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS 937
            +P T +   G  + ++ + +  ++ F FG ++ +SG +               GF +G+ 
Sbjct: 49   QPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGT---------------GFSLGIG 93

Query: 938  SDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTP 997
            +   +++  +     + P G   FG+ S              N    +SS +++     P
Sbjct: 94   ASKLNLSNTAATPAMANPSG---FGLGS-------------SNLTNAISSTVTSSQGTAP 137

Query: 998  --FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIET 1055
              F FG S           P ++S GFSF  G   ST  P          S FN+G+   
Sbjct: 138  TGFVFGPST------TSVAPATTSGGFSFTGG---STAQP----------SGFNIGSAGN 178

Query: 1056 KSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPAS-LPSASVFVLGRTEEKQQEPVTST 1114
             +   AP T   +       PAT    + G  +PA+  P+A++   G +         ++
Sbjct: 179  SAQPTAPATLPFT-------PATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTS 231

Query: 1115 SLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFG 1174
            S   G         C PV + G         S K+  + S T  +   +   A AT    
Sbjct: 232  SATTGLSL------CTPVTTAGAPTAGTQGFSLKAPGAASGTSTT---TSTAATATATTT 282

Query: 1175 AQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSS 1219
            + +STT      KP+      S+++++  A    G   G++ SS+
Sbjct: 283  SSSSTTGFALNLKPLAPAGIPSNTAAAVTAPPGPGAAAGAAASSA 327



 Score = 31.2 bits (69), Expect = 7.7
 Identities = 66/299 (22%), Positives = 107/299 (35%), Gaps = 33/299 (11%)

Query: 369 TPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYP 428
           T K  +        F  S T    F    Q   +  STG     T  Q    + +GF++ 
Sbjct: 20  TAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLAT--QTPATQTTGFTFG 77

Query: 429 NFSLPAAN-GLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSS--SLP 485
             +L +   G S G+G     +         + P         +   IS  +TSS  + P
Sbjct: 78  TATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQGTAP 137

Query: 486 TFNFSSPEITTSSPSPINS-------SQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEAN 538
           T     P  T+ +P+  +        S A  +   + S  ++  P    + P   +T A 
Sbjct: 138 TGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPA- 196

Query: 539 VLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598
               ++ G T       TA ++ +  +L   I+++     T   + C  TP      P  
Sbjct: 197 ---ATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLC--TPVTTAGAP-- 249

Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLK 657
                  G+    LK+PG AS    + +   TAT        A ++ SSS  GF  +LK
Sbjct: 250 -----TAGTQGFSLKAPGAASGTSTTTSTAATAT--------ATTTSSSSTTGFALNLK 295


>gi|24497605 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 74.7 bits (182), Expect = 6e-13
 Identities = 83/278 (29%), Positives = 119/278 (42%), Gaps = 37/278 (13%)

Query: 1197 SSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQS----SNPVSSSAFGNTAESSTSQSL 1252
            S ++ TPAT   G  FG++T +S     +   G S    SN  ++ A  N +      S 
Sbjct: 61   SLATQTPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSN 120

Query: 1253 LFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTG--- 1309
            L +  S    TSS GTA T FVFGP  +S    T+  GF  T  S++  S F  G+    
Sbjct: 121  LTNAISS-TVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNS 179

Query: 1310 --PSAPSASPAFGANQTPTFGQSQGASQPNPP--------GFGSISSSTALFPTGSQPAP 1359
              P+AP+  P   A    T   + GA+QP  P           S+ +S A  PT S    
Sbjct: 180  AQPTAPATLPFTPATPAAT---TAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTG 236

Query: 1360 PTFGTVSSSSQPPVFGQQ------PSQSAFGSGTTPNSSSA---FQFGSSTTNF--NFTN 1408
             +  T  +++  P  G Q      P  ++  S TT  +++A       SSTT F  N   
Sbjct: 237  LSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKP 296

Query: 1409 NSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446
             +P+G+      S+T AA   P G G      + +A T
Sbjct: 297  LAPAGI-----PSNTAAAVTAPPGPGAAAGAAASSAMT 329



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 78/289 (26%), Positives = 117/289 (40%), Gaps = 52/289 (17%)

Query: 1208 GGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTG 1267
            GG  FG++ +++  P   F F  S     +        +ST  + LFS  ++   T +TG
Sbjct: 14   GGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTG 73

Query: 1268 ---------TAVTPFVFGPGAS----SNNTTT------SGFGFGAT--------TTSSSA 1300
                     +  T F  G GAS    SN   T      SGFG G++        T +SS 
Sbjct: 74   FTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQ 133

Query: 1301 GSS---FVFGTGPSAPSASPAFGANQTPTFGQS-QGASQPNPPGFGSISSSTALFPTGSQ 1356
            G++   FVFG  PS  S +PA     T + G S  G S   P GF   S+  +  PT   
Sbjct: 134  GTAPTGFVFG--PSTTSVAPA-----TTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPA 186

Query: 1357 PAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFT 1416
              P T  T ++++        P+ +A  + T P+      F S  T       +P+   T
Sbjct: 187  TLPFTPATPAATTAGATQPAAPTPTATITSTGPS-----LFASIAT-------APTSSAT 234

Query: 1417 FGANSSTP--AASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463
             G +  TP   A A  +G+ GF      AA    +      +++ T+ S
Sbjct: 235  TGLSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTS 283



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 64/206 (31%), Positives = 83/206 (40%), Gaps = 34/206 (16%)

Query: 1266 TGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSF--VFGTGPSAPSASPAFGANQ 1323
            TG     F FG   ++  T  +GF F   +TS + G +F   F    S PS      A Q
Sbjct: 9    TGAPTGGFTFGTAKTATTTPATGFSF---STSGTGGFNFGAPFQPATSTPSTGLFSLATQ 65

Query: 1324 TP-------TFGQSQGASQPNPPGFGSISSSTALFPTGSQPA---PPTFGTVSSSSQPPV 1373
            TP       TFG +  AS       G  +S   L  T + PA   P  FG  SS+    +
Sbjct: 66   TPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAI 125

Query: 1374 FGQQPSQSAFGSGTTPNSSSAFQFGSSTTN---------FNFTNNSPSGVFTFGANSSTP 1424
                 S      GT P   + F FG STT+         F+FT  S +     G N  + 
Sbjct: 126  ----SSTVTSSQGTAP---TGFVFGPSTTSVAPATTSGGFSFTGGSTAQ--PSGFNIGSA 176

Query: 1425 AASAQPSGSGGFPFN-QSPAAFTVGS 1449
              SAQP+     PF   +PAA T G+
Sbjct: 177  GNSAQPTAPATLPFTPATPAATTAGA 202



 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 51/188 (27%), Positives = 76/188 (40%), Gaps = 37/188 (19%)

Query: 1287 SGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISS 1346
            SGF FG T    +    F FGT  +A +         TP  G S   S      FG+   
Sbjct: 2    SGFNFGGT---GAPTGGFTFGTAKTATT---------TPATGFSFSTSGTGGFNFGA--- 46

Query: 1347 STALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNF 1406
                 P     + P+ G  S ++Q P    Q +   FG+ T  +  + F  G   +  N 
Sbjct: 47   -----PFQPATSTPSTGLFSLATQTP--ATQTTGFTFGTATLASGGTGFSLGIGASKLNL 99

Query: 1407 TNN-------SPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNV---FS 1456
            +N        +PSG F  G+++ T A S+  + S G     +P  F  G +  +V    +
Sbjct: 100  SNTAATPAMANPSG-FGLGSSNLTNAISSTVTSSQG----TAPTGFVFGPSTTSVAPATT 154

Query: 1457 SSGTSFSG 1464
            S G SF+G
Sbjct: 155  SGGFSFTG 162



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 86/378 (22%), Positives = 129/378 (34%), Gaps = 85/378 (22%)

Query: 949  GFKFS---KPIGDFKFGVSSESKPEEVK----KDSKNDNFKFGL---------SSGLSNP 992
            GF F     P G F FG +  +            S    F FG          S+GL + 
Sbjct: 3    GFNFGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSL 62

Query: 993  VSLTP------FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKS 1046
             + TP      F FG + L           S   GFS G G      +         N S
Sbjct: 63   ATQTPATQTTGFTFGTATLA----------SGGTGFSLGIGASKLNLSNTAATPAMANPS 112

Query: 1047 SFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFG----NVEPASLPSASVFVLGR 1102
             F LG+    +A  +  T     A          GF FG    +V PA+      F  G 
Sbjct: 113  GFGLGSSNLTNAISSTVTSSQGTAPT--------GFVFGPSTTSVAPATTSGGFSFTGGS 164

Query: 1103 TEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKE 1162
            T +                     P    + S GNS Q     ++ +T  F+   P+   
Sbjct: 165  TAQ---------------------PSGFNIGSAGNSAQP----TAPATLPFTPATPAATT 199

Query: 1163 S--EQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSST-------PATSAGGGIFG 1213
            +   QPA  T      T+T    G +  +F+ +  + +SS+T       P T+AG    G
Sbjct: 200  AGATQPAAPT-----PTATITSTGPS--LFASIATAPTSSATTGLSLCTPVTTAGAPTAG 252

Query: 1214 SSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPF 1273
            +   S   P A      +++  +++    T+ SST+   L  +    A   S   A    
Sbjct: 253  TQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKPLAPAGIPSNTAAAVTA 312

Query: 1274 VFGPGASSNNTTTSGFGF 1291
              GPGA++    +S   +
Sbjct: 313  PPGPGAAAGAAASSAMTY 330



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 74/345 (21%), Positives = 131/345 (37%), Gaps = 69/345 (20%)

Query: 878  KPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS 937
            +P T +   G  + ++ + +  ++ F FG ++ +SG +               GF +G+ 
Sbjct: 49   QPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGT---------------GFSLGIG 93

Query: 938  SDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTP 997
            +   +++  +     + P G   FG+ S              N    +SS +++     P
Sbjct: 94   ASKLNLSNTAATPAMANPSG---FGLGS-------------SNLTNAISSTVTSSQGTAP 137

Query: 998  --FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIET 1055
              F FG S           P ++S GFSF  G   ST  P          S FN+G+   
Sbjct: 138  TGFVFGPST------TSVAPATTSGGFSFTGG---STAQP----------SGFNIGSAGN 178

Query: 1056 KSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPAS-LPSASVFVLGRTEEKQQEPVTST 1114
             +   AP T   +       PAT    + G  +PA+  P+A++   G +         ++
Sbjct: 179  SAQPTAPATLPFT-------PATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTS 231

Query: 1115 SLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFG 1174
            S   G         C PV + G         S K+  + S T  +   +   A AT    
Sbjct: 232  SATTGLSL------CTPVTTAGAPTAGTQGFSLKAPGAASGTSTT---TSTAATATATTT 282

Query: 1175 AQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSS 1219
            + +STT      KP+      S+++++  A    G   G++ SS+
Sbjct: 283  SSSSTTGFALNLKPLAPAGIPSNTAAAVTAPPGPGAAAGAAASSA 327



 Score = 31.2 bits (69), Expect = 7.7
 Identities = 66/299 (22%), Positives = 107/299 (35%), Gaps = 33/299 (11%)

Query: 369 TPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYP 428
           T K  +        F  S T    F    Q   +  STG     T  Q    + +GF++ 
Sbjct: 20  TAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLAT--QTPATQTTGFTFG 77

Query: 429 NFSLPAAN-GLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSS--SLP 485
             +L +   G S G+G     +         + P         +   IS  +TSS  + P
Sbjct: 78  TATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQGTAP 137

Query: 486 TFNFSSPEITTSSPSPINS-------SQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEAN 538
           T     P  T+ +P+  +        S A  +   + S  ++  P    + P   +T A 
Sbjct: 138 TGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPA- 196

Query: 539 VLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598
               ++ G T       TA ++ +  +L   I+++     T   + C  TP      P  
Sbjct: 197 ---ATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLC--TPVTTAGAP-- 249

Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLK 657
                  G+    LK+PG AS    + +   TAT        A ++ SSS  GF  +LK
Sbjct: 250 -----TAGTQGFSLKAPGAASGTSTTTSTAATAT--------ATTTSSSSTTGFALNLK 295


>gi|24497603 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 74.7 bits (182), Expect = 6e-13
 Identities = 83/278 (29%), Positives = 119/278 (42%), Gaps = 37/278 (13%)

Query: 1197 SSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQS----SNPVSSSAFGNTAESSTSQSL 1252
            S ++ TPAT   G  FG++T +S     +   G S    SN  ++ A  N +      S 
Sbjct: 61   SLATQTPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSN 120

Query: 1253 LFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTG--- 1309
            L +  S    TSS GTA T FVFGP  +S    T+  GF  T  S++  S F  G+    
Sbjct: 121  LTNAISS-TVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNS 179

Query: 1310 --PSAPSASPAFGANQTPTFGQSQGASQPNPP--------GFGSISSSTALFPTGSQPAP 1359
              P+AP+  P   A    T   + GA+QP  P           S+ +S A  PT S    
Sbjct: 180  AQPTAPATLPFTPATPAAT---TAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTG 236

Query: 1360 PTFGTVSSSSQPPVFGQQ------PSQSAFGSGTTPNSSSA---FQFGSSTTNF--NFTN 1408
             +  T  +++  P  G Q      P  ++  S TT  +++A       SSTT F  N   
Sbjct: 237  LSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKP 296

Query: 1409 NSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446
             +P+G+      S+T AA   P G G      + +A T
Sbjct: 297  LAPAGI-----PSNTAAAVTAPPGPGAAAGAAASSAMT 329



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 78/289 (26%), Positives = 117/289 (40%), Gaps = 52/289 (17%)

Query: 1208 GGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTG 1267
            GG  FG++ +++  P   F F  S     +        +ST  + LFS  ++   T +TG
Sbjct: 14   GGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTG 73

Query: 1268 ---------TAVTPFVFGPGAS----SNNTTT------SGFGFGAT--------TTSSSA 1300
                     +  T F  G GAS    SN   T      SGFG G++        T +SS 
Sbjct: 74   FTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQ 133

Query: 1301 GSS---FVFGTGPSAPSASPAFGANQTPTFGQS-QGASQPNPPGFGSISSSTALFPTGSQ 1356
            G++   FVFG  PS  S +PA     T + G S  G S   P GF   S+  +  PT   
Sbjct: 134  GTAPTGFVFG--PSTTSVAPA-----TTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPA 186

Query: 1357 PAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFT 1416
              P T  T ++++        P+ +A  + T P+      F S  T       +P+   T
Sbjct: 187  TLPFTPATPAATTAGATQPAAPTPTATITSTGPS-----LFASIAT-------APTSSAT 234

Query: 1417 FGANSSTP--AASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463
             G +  TP   A A  +G+ GF      AA    +      +++ T+ S
Sbjct: 235  TGLSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTS 283



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 64/206 (31%), Positives = 83/206 (40%), Gaps = 34/206 (16%)

Query: 1266 TGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSF--VFGTGPSAPSASPAFGANQ 1323
            TG     F FG   ++  T  +GF F   +TS + G +F   F    S PS      A Q
Sbjct: 9    TGAPTGGFTFGTAKTATTTPATGFSF---STSGTGGFNFGAPFQPATSTPSTGLFSLATQ 65

Query: 1324 TP-------TFGQSQGASQPNPPGFGSISSSTALFPTGSQPA---PPTFGTVSSSSQPPV 1373
            TP       TFG +  AS       G  +S   L  T + PA   P  FG  SS+    +
Sbjct: 66   TPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAI 125

Query: 1374 FGQQPSQSAFGSGTTPNSSSAFQFGSSTTN---------FNFTNNSPSGVFTFGANSSTP 1424
                 S      GT P   + F FG STT+         F+FT  S +     G N  + 
Sbjct: 126  ----SSTVTSSQGTAP---TGFVFGPSTTSVAPATTSGGFSFTGGSTAQ--PSGFNIGSA 176

Query: 1425 AASAQPSGSGGFPFN-QSPAAFTVGS 1449
              SAQP+     PF   +PAA T G+
Sbjct: 177  GNSAQPTAPATLPFTPATPAATTAGA 202



 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 51/188 (27%), Positives = 76/188 (40%), Gaps = 37/188 (19%)

Query: 1287 SGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISS 1346
            SGF FG T    +    F FGT  +A +         TP  G S   S      FG+   
Sbjct: 2    SGFNFGGT---GAPTGGFTFGTAKTATT---------TPATGFSFSTSGTGGFNFGA--- 46

Query: 1347 STALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNF 1406
                 P     + P+ G  S ++Q P    Q +   FG+ T  +  + F  G   +  N 
Sbjct: 47   -----PFQPATSTPSTGLFSLATQTP--ATQTTGFTFGTATLASGGTGFSLGIGASKLNL 99

Query: 1407 TNN-------SPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNV---FS 1456
            +N        +PSG F  G+++ T A S+  + S G     +P  F  G +  +V    +
Sbjct: 100  SNTAATPAMANPSG-FGLGSSNLTNAISSTVTSSQG----TAPTGFVFGPSTTSVAPATT 154

Query: 1457 SSGTSFSG 1464
            S G SF+G
Sbjct: 155  SGGFSFTG 162



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 86/378 (22%), Positives = 129/378 (34%), Gaps = 85/378 (22%)

Query: 949  GFKFS---KPIGDFKFGVSSESKPEEVK----KDSKNDNFKFGL---------SSGLSNP 992
            GF F     P G F FG +  +            S    F FG          S+GL + 
Sbjct: 3    GFNFGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSL 62

Query: 993  VSLTP------FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKS 1046
             + TP      F FG + L           S   GFS G G      +         N S
Sbjct: 63   ATQTPATQTTGFTFGTATLA----------SGGTGFSLGIGASKLNLSNTAATPAMANPS 112

Query: 1047 SFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFG----NVEPASLPSASVFVLGR 1102
             F LG+    +A  +  T     A          GF FG    +V PA+      F  G 
Sbjct: 113  GFGLGSSNLTNAISSTVTSSQGTAPT--------GFVFGPSTTSVAPATTSGGFSFTGGS 164

Query: 1103 TEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKE 1162
            T +                     P    + S GNS Q     ++ +T  F+   P+   
Sbjct: 165  TAQ---------------------PSGFNIGSAGNSAQP----TAPATLPFTPATPAATT 199

Query: 1163 S--EQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSST-------PATSAGGGIFG 1213
            +   QPA  T      T+T    G +  +F+ +  + +SS+T       P T+AG    G
Sbjct: 200  AGATQPAAPT-----PTATITSTGPS--LFASIATAPTSSATTGLSLCTPVTTAGAPTAG 252

Query: 1214 SSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPF 1273
            +   S   P A      +++  +++    T+ SST+   L  +    A   S   A    
Sbjct: 253  TQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKPLAPAGIPSNTAAAVTA 312

Query: 1274 VFGPGASSNNTTTSGFGF 1291
              GPGA++    +S   +
Sbjct: 313  PPGPGAAAGAAASSAMTY 330



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 74/345 (21%), Positives = 131/345 (37%), Gaps = 69/345 (20%)

Query: 878  KPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVS 937
            +P T +   G  + ++ + +  ++ F FG ++ +SG +               GF +G+ 
Sbjct: 49   QPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGT---------------GFSLGIG 93

Query: 938  SDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTP 997
            +   +++  +     + P G   FG+ S              N    +SS +++     P
Sbjct: 94   ASKLNLSNTAATPAMANPSG---FGLGS-------------SNLTNAISSTVTSSQGTAP 137

Query: 998  --FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIET 1055
              F FG S           P ++S GFSF  G   ST  P          S FN+G+   
Sbjct: 138  TGFVFGPST------TSVAPATTSGGFSFTGG---STAQP----------SGFNIGSAGN 178

Query: 1056 KSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPAS-LPSASVFVLGRTEEKQQEPVTST 1114
             +   AP T   +       PAT    + G  +PA+  P+A++   G +         ++
Sbjct: 179  SAQPTAPATLPFT-------PATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTS 231

Query: 1115 SLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFG 1174
            S   G         C PV + G         S K+  + S T  +   +   A AT    
Sbjct: 232  SATTGLSL------CTPVTTAGAPTAGTQGFSLKAPGAASGTSTT---TSTAATATATTT 282

Query: 1175 AQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSS 1219
            + +STT      KP+      S+++++  A    G   G++ SS+
Sbjct: 283  SSSSTTGFALNLKPLAPAGIPSNTAAAVTAPPGPGAAAGAAASSA 327



 Score = 31.2 bits (69), Expect = 7.7
 Identities = 66/299 (22%), Positives = 107/299 (35%), Gaps = 33/299 (11%)

Query: 369 TPKPVSIATNRSVYFKPSLTPSGEFRKTNQRIDNKCSTGYEKNMTPGQNREQRESGFSYP 428
           T K  +        F  S T    F    Q   +  STG     T  Q    + +GF++ 
Sbjct: 20  TAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLAT--QTPATQTTGFTFG 77

Query: 429 NFSLPAAN-GLSSGVGGGGGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSS--SLP 485
             +L +   G S G+G     +         + P         +   IS  +TSS  + P
Sbjct: 78  TATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQGTAP 137

Query: 486 TFNFSSPEITTSSPSPINS-------SQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEAN 538
           T     P  T+ +P+  +        S A  +   + S  ++  P    + P   +T A 
Sbjct: 138 TGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPA- 196

Query: 539 VLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598
               ++ G T       TA ++ +  +L   I+++     T   + C  TP      P  
Sbjct: 197 ---ATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLC--TPVTTAGAP-- 249

Query: 599 PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLK 657
                  G+    LK+PG AS    + +   TAT        A ++ SSS  GF  +LK
Sbjct: 250 -----TAGTQGFSLKAPGAASGTSTTTSTAATAT--------ATTTSSSSTTGFALNLK 295


>gi|89276766 trophinin isoform 5 [Homo sapiens]
          Length = 1431

 Score = 74.7 bits (182), Expect = 6e-13
 Identities = 177/705 (25%), Positives = 250/705 (35%), Gaps = 108/705 (15%)

Query: 824  SVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKS 883
            S  AS S+T  +S   GG+L          S         + + S++        P T +
Sbjct: 764  STSASFSNTASISF--GGTLSTSSSFSSAASISFGCAHSTSTSFSSEASISFGGMPCTSA 821

Query: 884  GFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFK--------FGDQGG---- 931
             F G  +SS S   + S++F  G SS   G   TL++T  F         FG        
Sbjct: 822  SFSGGVSSSFSGPLSTSATFSGGASSGFGG---TLSTTAGFSGVLSTSTSFGSAPTTSTV 878

Query: 932  FKIGVSSDSGSINPMSEGFKFS-KPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLS 990
            F   +S+ +G    +S    F   P     FG +  +          +  F   LS+ +S
Sbjct: 879  FSSALSTSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVS 938

Query: 991  -NPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSE------ 1043
                S T   FG    G          S S G  FG G +N++ +  + + TS       
Sbjct: 939  FGGSSSTSANFG----GTLSTSICFDGSPSTGAGFG-GALNTSASFGSVLNTSTGFGGAM 993

Query: 1044 NKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRT 1103
            + S+   GT+ T            S        A  GG    N +     S SV   G  
Sbjct: 994  STSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSP 1053

Query: 1104 EEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSK-STFSFSMTKPSEKE 1162
                     STS  FG   +          SFG +  T    S   ST +     P    
Sbjct: 1054 ---------STSAGFGGALNTNA-------SFGCAVSTSASFSGAVSTSACFSGAPITNP 1097

Query: 1163 SEQPAKATFA-FGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAG-GGIFGSSTSSSN 1220
                A +T A FG   ST AD G         +NS    + P+TS   GG  G+S     
Sbjct: 1098 GFGGAFSTSAGFGGALSTAADFGGTP------SNSIGFGAAPSTSVSFGGAHGTSLCFGG 1151

Query: 1221 PPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGAS 1280
             P  +  FG +SN  ++  FG    +S   S   S       ++STG     F FG G S
Sbjct: 1152 APSTSLCFGSASN--TNLCFGGPPSTSACFSGATSPSFCDGPSTSTG-----FSFGNGLS 1204

Query: 1281 SNN------TTTSGFGFGATTTSSSAG-----SSFVFGTGPSA-----PSASPAFGANQT 1324
            +N        T++GFG G  T++  +G     S F  G G SA     P  S  FG    
Sbjct: 1205 TNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGFGGGLG 1264

Query: 1325 PTFGQSQGASQP--------NPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQ 1376
             + G S G               GFG    + A F +    +    G +S+S     FG 
Sbjct: 1265 TSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGGLSTSDG---FGS 1321

Query: 1377 QPSQS---------AFGSGTT--------PNSSSAFQFGSSTTNFNFTNNSPSGVFTFGA 1419
            +P+ S          FGSG+         P++S+ F  G S+    F+    +GV  F +
Sbjct: 1322 RPNASFDRGLSTIIGFGSGSNTSTGFTGEPSTSTGFSSGPSSI-VGFSGGPSTGV-GFCS 1379

Query: 1420 NSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFSG 1464
              ST   S  PS   GF    +  A   G    +    SG +  G
Sbjct: 1380 GPSTSGFSGGPSTGAGFGGGPNTGAGFGGGPSTSAGFGSGAASLG 1424



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 151/593 (25%), Positives = 216/593 (36%), Gaps = 117/593 (19%)

Query: 960  KFGVSSESKPEEVKKDSKNDNFKFGLSS--GLSNPVSLTPFQFGVSNLGQEEKKEELPKS 1017
            +F    E++ +E    S N NF  G S+  G S+  S++   F  +             S
Sbjct: 702  RFSFEIEARAQENADASTNVNFSRGASTRAGFSDGASIS---FNGA------------PS 746

Query: 1018 SSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS----ASVAPFTC--KTSEAK 1071
            SS GFS G G+     AP+ +   S   S    GT+ T S    A+   F C   TS + 
Sbjct: 747  SSGGFSGGPGITFGV-APSTSASFSNTASISFGGTLSTSSSFSSAASISFGCAHSTSTSF 805

Query: 1072 KEE-------MPATKGGFSFGNVEPASLP----------SASVFVLGRTEEKQQEPVTST 1114
              E       MP T   FS G     S P          ++S F    +       V ST
Sbjct: 806  SSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAGFSGVLST 865

Query: 1115 SLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFG 1174
            S  FG       P    VFS   S  T       ++  F  +  S          +  FG
Sbjct: 866  STSFGSA-----PTTSTVFSSALSTSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFG 920

Query: 1175 AQTSTTADQGAAKPVFSFLNNSSSSSS--------------TPATSAG-GGIFGSSTSSS 1219
                T+   G           SSS+S+              +P+T AG GG   +S S  
Sbjct: 921  GSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDGSPSTGAGFGGALNTSASFG 980

Query: 1220 NPPVATFVFGQSSNPVSSSAFGNTAESST----SQSLLFSQDSKLATTSSTGTAV----- 1270
            +    +  FG + +  +S+ FG T  +S     S     S  S L T +  G AV     
Sbjct: 981  SVLNTSTGFGGAMS--TSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGGAVSTNTD 1038

Query: 1271 ------TPFVFGPGASSNN------TTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPA 1318
                  T   FG   S++        T + FG   +T++S +G+         AP  +P 
Sbjct: 1039 FGGTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVSTSASFSGAVSTSACFSGAPITNPG 1098

Query: 1319 FGANQTPTFG--------QSQGASQPNPPGFGSISSS---------TALFPTGSQPAPPT 1361
            FG   + + G           G +  N  GFG+  S+         T+L   G+      
Sbjct: 1099 FGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSVSFGGAHGTSLCFGGAPSTSLC 1158

Query: 1362 FGTVSSSSQPPVFGQQPSQSAFGSGTT-------PNSSSAFQFGSS-TTNFNFTN--NSP 1411
            FG+ S+++    FG  PS SA  SG T       P++S+ F FG+  +TN  F    N+ 
Sbjct: 1159 FGSASNTNL--CFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTNAGFGGGLNTS 1216

Query: 1412 SGVFTFGANSSTPAA-SAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463
            +G   FG    T A  S   S S GF      +A   G  G +     G   S
Sbjct: 1217 AG---FGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGFGGGLGTS 1266



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 105/352 (29%), Positives = 157/352 (44%), Gaps = 51/352 (14%)

Query: 1139 EQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSS 1198
            E+  D+  + S FSF +   +++ ++      F+ GA T      GA+    SF  N + 
Sbjct: 691  EELGDDAQAWSRFSFEIEARAQENADASTNVNFSRGASTRAGFSDGAS---ISF--NGAP 745

Query: 1199 SSSTPATSAGGGIFG--SSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESS----TSQSL 1252
            SSS   +   G  FG   STS+S    A+  FG + +  +SS+F + A  S     S S 
Sbjct: 746  SSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLS--TSSSFSSAASISFGCAHSTST 803

Query: 1253 LFSQDSKLA------TTSSTGTAVTPFVFGP---GASSNNTTTSGFGFGATTTSSSAGSS 1303
             FS ++ ++      T++S    V+    GP    A+ +   +SGFG    T S++AG S
Sbjct: 804  SFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFG---GTLSTTAGFS 860

Query: 1304 FVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFG 1363
             V  T  S  SA         PT      ++     GFG I S++  F  GS  +  +FG
Sbjct: 861  GVLSTSTSFGSA---------PTTSTVFSSALSTSTGFGGILSTSVCF-GGSPSSSGSFG 910

Query: 1364 TVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNF---------TNNSPSGV 1414
               S+S    FG  P  S  G G T ++S +F  GSS+T+ NF          + SPS  
Sbjct: 911  GTLSTS--ICFGGSPCTST-GFGGTLSTSVSFG-GSSSTSANFGGTLSTSICFDGSPSTG 966

Query: 1415 FTFGANSSTPAA-SAQPSGSGGFPFNQSPAAFTVGSNGKNVF--SSSGTSFS 1463
              FG   +T A+  +  + S GF    S +A   G+   +V    S GTS S
Sbjct: 967  AGFGGALNTSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVS 1018



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 68/245 (27%), Positives = 98/245 (40%), Gaps = 20/245 (8%)

Query: 1231 SSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFG 1290
            S+N   S      A  S   S+ F+     +   S G  +T F   P  S++ + T+   
Sbjct: 718  STNVNFSRGASTRAGFSDGASISFNGAPSSSGGFSGGPGIT-FGVAPSTSASFSNTASIS 776

Query: 1291 FGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTAL 1350
            FG T ++SS+ SS    +   A S S +F +  + +FG   G    +    G +SSS   
Sbjct: 777  FGGTLSTSSSFSSAASISFGCAHSTSTSFSSEASISFG---GMPCTSASFSGGVSSSF-- 831

Query: 1351 FPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNS 1410
              +G      TF   +SS     FG   S +A  SG    S+S   FGS+ T     +++
Sbjct: 832  --SGPLSTSATFSGGASSG----FGGTLSTTAGFSGVLSTSTS---FGSAPTTSTVFSSA 882

Query: 1411 PSGVFTFGANSSTPAA-SAQPSGSGGFPFNQSPAAFTVG----SNGKNVFSSSGTSFSGR 1465
             S    FG   ST       PS SG F    S +    G    S G     S+  SF G 
Sbjct: 883  LSTSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGS 942

Query: 1466 KIKTA 1470
               +A
Sbjct: 943  SSTSA 947



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 36/154 (23%), Positives = 61/154 (39%), Gaps = 11/154 (7%)

Query: 770  MTASSSSCTVTTGTLGFGDKFKRPI---GSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
            +  S+S  +V   + GFG          G+   SVC   +        S ++   G    
Sbjct: 973  LNTSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGGA 1032

Query: 827  ASSSS----TVPVSLPSGGS----LGLEKFKKPEGSWDCELCLVQNKADSTKCLACESAK 878
             S+++    T+  S+  GGS     G         S+ C +    + + +    AC S  
Sbjct: 1033 VSTNTDFGGTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVSTSASFSGAVSTSACFSGA 1092

Query: 879  PGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSS 912
            P T  GF G  ++S+    A S++  FG + S+S
Sbjct: 1093 PITNPGFGGAFSTSAGFGGALSTAADFGGTPSNS 1126


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 211/1005 (20%), Positives = 341/1005 (33%), Gaps = 190/1005 (18%)

Query: 470  PVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSS 529
            P  P  S   T SS P   +   ++TT++                T+  STGS     S+
Sbjct: 4200 PSTPATSSTATPSSTPGTTWILTKLTTTA----------------TTTESTGSTATPSST 4243

Query: 530  PIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKT 588
            P    T   +  PS+   T +VP   TA  S + +T   P +S++A   TT   T+ K T
Sbjct: 4244 P---GTTWILTEPSTTA-TVTVPTGSTATASSTQATAGTPHVSTTA---TTPTVTSSKAT 4296

Query: 589  PPEDCEGPFRPAEILKEGSVLDILKSPGFAS--PKIDSVAAQPTATSPVVYTRPAISSFS 646
            P                        SPG A+  P + S A  PTATS   +T    SS  
Sbjct: 4297 P----------------------FSSPGTATALPALRSTATTPTATS---FTAIPSSSLG 4331

Query: 647  SSGIGFGESLKAGSSWQCDT-----------CLLQNKVTDNKCIACQAAKLSPRDTAKQT 695
            ++     ++    ++    T            +L    T  +     A   S   TA  T
Sbjct: 4332 TTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTT 4391

Query: 696  GIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVK 755
             + T   +G T   +S  G   +  PV   W   T      P         +  PGT   
Sbjct: 4392 KVPTTTTTGFTVTPSSSPGTA-RTPPV---WISTT----TTPTTSGSTVTPSSVPGTTHT 4443

Query: 756  RALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVS 815
              +  T  +  A    A+ SS T T+GT                               +
Sbjct: 4444 PTVLTTTTTTVATGSMATPSSSTQTSGT------------------------THTPPVPN 4479

Query: 816  CMSEKPGSSVPASSSSTVPVSLPS--GGSLGLEKFKKPE-GSWDCELCLVQNKADSTKCL 872
              +   G S+  SS  TV  +  S   G+LG     +P  G+             ST  L
Sbjct: 4480 TTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPAL 4539

Query: 873  ACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGF 932
            +       T        T++    +A S       +++++ PS+T TST           
Sbjct: 4540 SSPHPSSRTTESPPSPGTTTPGHTTATSR------TTATATPSKTRTSTLLPSSPTSAPI 4593

Query: 933  KIGVSSDSGSINPMSEGFKFSKPI-----GDF----KFGVSSESKPEEVKKDSKNDNFKF 983
               V++        SE   +S P+     GDF        +  +  E+          + 
Sbjct: 4594 TTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQP 4653

Query: 984  GLSSGLSNPVSLTPFQFGV--SNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVT 1041
            G+  G    V      FG+   N  Q  K +         F    G   STPA ++T + 
Sbjct: 4654 GVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMP 4713

Query: 1042 SENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLG 1101
            S    +  + T  T +A+                 A+ G  +  +  P + P   V    
Sbjct: 4714 SSTPGTTWILTELTTTATTT---------------ASTGSTATPSSTPGTAPPPKVLT-- 4756

Query: 1102 RTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSS-----KSTFSFSMT 1156
                    P T+ +    K   +  P+         S  TK   +S      ST   + T
Sbjct: 4757 -------SPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGT 4809

Query: 1157 KPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSST 1216
             P +  +     +T    +   TT               ++ +++T ATS+      +ST
Sbjct: 4810 LPEQTTTPVATMSTIHPSSTPETTHTSTVL---------TTKATTTRATSS------TST 4854

Query: 1217 SSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS---LLFSQDSKLATTSSTGTAVTP- 1272
             SS P     +   ++   +++A G TA  S++     +L    +   TT+STG+  TP 
Sbjct: 4855 PSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPS 4914

Query: 1273 -------FVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTP 1325
                    +  P  ++  T  +G    A++T ++AG+  V  T               TP
Sbjct: 4915 STPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTA-------------TTP 4961

Query: 1326 TFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVF---GQQPSQSA 1382
            T   S+     +P   G+ ++  AL  T + P   +F  + SSS    +    Q  + +A
Sbjct: 4962 TVTSSKATPSSSP---GTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTA 5018

Query: 1383 FGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAAS 1427
              S  TP+S+      S+      T    +G  +    SSTP  +
Sbjct: 5019 TMSTATPSSTPETVHTSTVLTATATTTGATG--SVATPSSTPGTA 5061



 Score = 57.8 bits (138), Expect = 8e-08
 Identities = 222/1034 (21%), Positives = 342/1034 (33%), Gaps = 157/1034 (15%)

Query: 470  PVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSS 529
            P  P  S     SS P   +   E+TT++                T+  STGS     S+
Sbjct: 3053 PSTPATSSTAMPSSTPGTTWILTELTTTA----------------TTTESTGSTATPSST 3096

Query: 530  PIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTL-EPIISSSAHHVTTVNSTNCKKT 588
            P    T   +  PS+   T +VP   TA  S + +T   P +S++A   TT   T+ K T
Sbjct: 3097 P---GTTWILTEPSTTA-TVTVPTGSTATASSTQATAGTPHVSTTA---TTPTVTSSKAT 3149

Query: 589  PPEDCEGPFRPAEILKEGSVLDILKSPGFAS--PKIDSVAAQPTATSPVVYTRPAISSFS 646
            P                        SPG A+  P + S A  PTATS         ++  
Sbjct: 3150 P----------------------FSSPGTATALPALRSTATTPTATS--------FTAIP 3179

Query: 647  SSGIGFGESLKAGSSWQCDTCLLQNKVTDNKCIACQAAKLSPRDTAKQTGIETPNKSGKT 706
            SS +G        ++W   +       T +        +     T   T   T   +G  
Sbjct: 3180 SSSLG--------TTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSV 3231

Query: 707  TLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSES 766
               +S  G     K +  T    T    + P   + +        T   R  T+T  S  
Sbjct: 3232 ATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIP 3291

Query: 767  AETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVP 826
              T T +  + T TT   G       P  S +      S         +  +   G S+ 
Sbjct: 3292 GTTHTPTVLTTTTTTVATG---SMATPSSSTQ-----TSGTTHTPPVPNTTATTHGRSLS 3343

Query: 827  ASSSSTVPVSLPSG--GSLGLEKFKKPE-GSWDCELCLVQNKADSTKCLACESAKPGTKS 883
             SS  TV  +  S   G+LG     +P  G+             ST  L+       T  
Sbjct: 3344 PSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTE 3403

Query: 884  GFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSI 943
                  T++     A S +      ++++ PS+T TST              V+      
Sbjct: 3404 SPPSPGTTTPGHTRATSRT------TATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQ 3457

Query: 944  NPMSEGFKFSKPI-----GDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLS----NPVS 994
               SE   +S P+     GDF    +  +    V +       +     G+       V 
Sbjct: 3458 CAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVV 3517

Query: 995  LTPFQFGV--SNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGT 1052
                 FG+   N  Q  K +         F    G   STPA ++T   S    +  + T
Sbjct: 3518 ECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILT 3577

Query: 1053 IETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVT 1112
             +T +A+                 AT G  +  +  P + P   V     T        T
Sbjct: 3578 EQTTAATTT---------------ATTGSTAIPSSTPGTAPPPKVLTSTATTP------T 3616

Query: 1113 STSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQP-AKATF 1171
            +TS      +        PV +   ++ T    +   +F+   T    +++  P A  + 
Sbjct: 3617 ATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMST 3676

Query: 1172 AFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGG-IFGSSTSSSNPPVATFVFGQ 1230
               + T  T          +    ++SS STP+++ G   I    T+++    AT   G 
Sbjct: 3677 IHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAAT---GP 3733

Query: 1231 SSNPVSSSAFGNT---AESSTSQSLLFSQDSKLATTSS----------TGTAVTPFVFGP 1277
            ++ P  SS  G T    E ST+ ++     S    +S+          T TA TP V   
Sbjct: 3734 TATP--SSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISS 3791

Query: 1278 GA---SSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGAS 1334
             A   SS  T T+     +T T+ +A S     +  S  +A        TPT   S    
Sbjct: 3792 RATPSSSPGTATALPALRSTATTPTATSVTAIPSS-SLGTAWTRLSQTTTPTATMSTATP 3850

Query: 1335 QPNPPGFGS----ISSSTALFPTGSQPAP-PTFGTVSSSSQPPV----FGQQPSQSA--- 1382
               P    +     +++T    TGS   P  T GT  ++  P      F   PS S    
Sbjct: 3851 SSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTA 3910

Query: 1383 ------FGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSS--TPAASAQPSGSG 1434
                    + TTP +  +    SS      T    +   T  A  S  TP++S Q SG+ 
Sbjct: 3911 LTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTT 3970

Query: 1435 GFPFNQSPAAFTVG 1448
              P   +  A T G
Sbjct: 3971 HTPPVPNTTATTHG 3984



 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 74/293 (25%), Positives = 124/293 (42%), Gaps = 35/293 (11%)

Query: 1155 MTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVF-SFLNNSSSSSSTPATSAGGGIFG 1213
            +T P+   +   +KAT +   +T+TT       PV  S    S+++S TP  S+  G  G
Sbjct: 4755 LTSPATTPTATSSKATSSSSPRTATTL------PVLTSTATKSTATSVTPIPSSTLGTTG 4808

Query: 1214 SSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSST-GT---- 1268
            +    +  PVAT     + +P S+    +T+   T+++      S  +T SST GT    
Sbjct: 4809 TLPEQTTTPVATM---STIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWIL 4865

Query: 1269 ------AVTPFVFGPGASSNNTT-TSGFGFGATTTSSSAGSSFVFGTGPSAPSAS----- 1316
                  A T    GP A+ ++T  T+      TTT+++  S+    T  S P  +     
Sbjct: 4866 TELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTE 4925

Query: 1317 PAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQ 1376
            P+  A  T   G +  AS           S+TA  PT       T    + SS P     
Sbjct: 4926 PSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPT------VTSSKATPSSSPGTATA 4979

Query: 1377 QPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQ 1429
             P+  +  + TTP ++S     SS+    +T  S +   T   +++TP+++ +
Sbjct: 4980 LPALRS--TATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE 5030



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 210/1042 (20%), Positives = 349/1042 (33%), Gaps = 129/1042 (12%)

Query: 454  TRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQ 513
            T ++ ++P     + VP     +   T ++  T     P ++T++ +P  +S   T    
Sbjct: 4246 TTWILTEPSTTATVTVPTGSTATASSTQATAGT-----PHVSTTATTPTVTSSKAT---P 4297

Query: 514  MTSP-SSTGSPMFKFSSPIVKSTEANVLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISS 572
             +SP ++T  P  + ++    +T    +P SS+G T++  +++T   + + ST  P  + 
Sbjct: 4298 FSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWT-RLSQTTTPTATMSTATPSSTP 4356

Query: 573  SAHHVTTVNSTNCKKT-------PPEDCEGPFRPAEI---LKEGSVLDILKSPGFA---- 618
               H +TV +T    T        P    G     ++      G  +    SPG A    
Sbjct: 4357 ETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPP 4416

Query: 619  -------SPKIDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLKAGSSWQCDTCLLQN 671
                   +P        P++     +T P + + +++ +  G      SS Q  +     
Sbjct: 4417 VWISTTTTPTTSGSTVTPSSVPGTTHT-PTVLTTTTTTVATGSMATPSSSTQ-TSGTTHT 4474

Query: 672  KVTDNKCIACQAAKLSPRD--TAKQTGIE-TPNKSGKTTLSASGTGFGDKFKPVIGTWDC 728
                N         LSP    T +      T    G T ++   TG         GT   
Sbjct: 4475 PPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQH 4534

Query: 729  DTCLVQNKPEAIKCVACETPKPGTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGD 788
             T  + + P          P PGT      T T    S  T TA+ S     T TL    
Sbjct: 4535 STPAL-SSPHPSSRTTESPPSPGTTTPGHTTAT----SRTTATATPSK--TRTSTLLPSS 4587

Query: 789  KFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKF 848
                PI +   + C                 +P  +       + P+  PSGG       
Sbjct: 4588 PTSAPITTVVTTGC-----------------EPQCAWSEWLDYSYPMPGPSGGDFDTYSN 4630

Query: 849  KKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGFKG------FDTSSSSSNSAASSS 902
             +  G   CE  L        +C A   A+PG   G  G       D      N      
Sbjct: 4631 IRAAGGAVCEQPL------GLECRA--QAQPGVPLGELGQVVECSLDFGLVCRNREQVGK 4682

Query: 903  FKFGVS--------SSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSEGFKFSK 954
            FK   +        +    PS   TS+        G   I     + +    S G   + 
Sbjct: 4683 FKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATP 4742

Query: 955  PIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQEEKKEEL 1014
                      +   P+ +   +         ++  S+P + T      S   +       
Sbjct: 4743 -----SSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVT 4797

Query: 1015 PKSSSAGFSFGTGVINSTP--APANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKK 1072
            P  SS   + GT    +T   A  +TI  S    + +  T+ T  A+    T  TS    
Sbjct: 4798 PIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTS---- 4853

Query: 1073 EEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEP--------VTSTSLVFGKKADN 1124
               P++  G ++   E  +  + +    G T      P        +T+T+         
Sbjct: 4854 --TPSSTPGTTWILTE-LTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGST 4910

Query: 1125 EEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFA-FGAQTSTTADQ 1183
              P   P  ++  +E +     +  T S +    ++  +  P  +T A     TS+ A  
Sbjct: 4911 ATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATP 4970

Query: 1184 GAAKPVFSFLNNSSSSSSTPATSAGGGIFGSS-------TSSSNPPVATFVFGQSSNPVS 1236
             ++    + L    S+++TP  ++   I  SS        S +  P AT     ++ P S
Sbjct: 4971 SSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATM---STATPSS 5027

Query: 1237 SSAFGNTAESSTSQSLLFSQDSKLATTSST-GTAVT---PFVFGPGASSNNTTTSGFGF- 1291
            +    +T+   T+ +        +AT SST GTA T   P     G ++  +++ G    
Sbjct: 5028 TPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALT 5087

Query: 1292 GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALF 1351
              TTT  S  S+    + P     S       T T   +  A+  +    G+    T L 
Sbjct: 5088 PPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSST--LGTTRILTELT 5145

Query: 1352 PTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSP 1411
             T +  A  T  T + SS P         S   +   P  S+A    SST     T ++P
Sbjct: 5146 TTATTTA-ATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTA--TASSTLG---TAHTP 5199

Query: 1412 SGVFTFGANSSTPAASAQPSGS 1433
              V T  A   T  AS  PS S
Sbjct: 5200 KVVTTM-ATMPTATASTVPSSS 5220



 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 67/286 (23%), Positives = 111/286 (38%), Gaps = 16/286 (5%)

Query: 1177 TSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVS 1236
            TS+TA   ++ P  +++    ++++T   S G     SST  + PP        ++ P +
Sbjct: 4707 TSSTA-MPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLT-SPATTPTA 4764

Query: 1237 SSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTT 1296
            +S+   ++ S  + + L    S    T ST T+VTP        S+   T+G     TTT
Sbjct: 4765 TSSKATSSSSPRTATTLPVLTS--TATKSTATSVTPI------PSSTLGTTGTLPEQTTT 4816

Query: 1297 SSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQ 1356
              +  S+    + P     S       T T   S  ++  + PG   I +      T + 
Sbjct: 4817 PVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTA 4876

Query: 1357 PAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFT 1416
               P   T + SS P         +   + T    S+A    +  T +  T  S +   T
Sbjct: 4877 ATGP---TATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVT 4933

Query: 1417 FGANSSTPAASAQPSGSGGFPFNQSPAAF-TVGSNGKNVFSSSGTS 1461
                S+  A+S Q   + G P   + A   TV S+     SS GT+
Sbjct: 4934 VPTGSTATASSTQ--ATAGTPHVSTTATTPTVTSSKATPSSSPGTA 4977



 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 79/337 (23%), Positives = 124/337 (36%), Gaps = 55/337 (16%)

Query: 1161 KESEQPAKATFAFGAQTSTTADQGAAKPVFS-----FLNNSSSSSSTPATSAGGGIFGSS 1215
            +E  Q  + +  FG         G  K  F+     F  N     STPATS+      ++
Sbjct: 4156 RELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSS------TA 4209

Query: 1216 TSSSNPPVATFVFGQSSNPVSSSAFGNTA-------------ESSTSQSLLFSQDSKLAT 1262
            T SS P     +   ++   ++ + G+TA             E ST+ ++     S    
Sbjct: 4210 TPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATA 4269

Query: 1263 TSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPS----ASPA 1318
            +S+  TA TP V     +   T++    F +  T+++  +     T P+A S     S +
Sbjct: 4270 SSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSS 4329

Query: 1319 FG---------ANQTPTFGQSQGASQPNPPGFGSISSSTALF--PTGSQPAP-PTFGTVS 1366
             G            T T   +  +S P      ++ ++TA     TGS   P  T GT  
Sbjct: 4330 LGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAH 4389

Query: 1367 SSSQPPV----FGQQPSQSA---------FGSGTTPNSSSAFQFGSSTTNFNFTNNSPSG 1413
            ++  P      F   PS S            + TTP +S +    SS      T    + 
Sbjct: 4390 TTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTT 4449

Query: 1414 VFTFGANSS--TPAASAQPSGSGGFPFNQSPAAFTVG 1448
              T  A  S  TP++S Q SG+   P   +  A T G
Sbjct: 4450 TTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHG 4486



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 77/330 (23%), Positives = 125/330 (37%), Gaps = 35/330 (10%)

Query: 1146 SSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPAT 1205
            SS    ++ +TKP+   +   +  + A    T  TA         +     +SS +TP++
Sbjct: 2591 SSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSS 2650

Query: 1206 SAGGGI-FGSSTSSSNPPVATFVFGQSSNPVSSSAFGNT-----AESSTSQSLLFSQDSK 1259
            S G      +  S++  P AT     S  P+ SS+ G T       ++ + ++  +  S 
Sbjct: 2651 SPGTATALPALRSTATTPTAT-----SVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSS 2705

Query: 1260 LATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAF 1319
               T+ T T +T      GA+ +  T S     A TT     ++  F    + PS+SP  
Sbjct: 2706 TPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGF---TATPSSSPGT 2762

Query: 1320 GAN-----QTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQ---- 1370
                     T T   ++G++       G+  ++T L  T +  A  +  T SSS+Q    
Sbjct: 2763 ALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGT 2822

Query: 1371 ---PPVFGQQ--------PSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGA 1419
               PPV            P  S     T   S+++   G++      T  S +   T G 
Sbjct: 2823 THTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGT 2882

Query: 1420 NS-STPAASAQPSGSGGFPFNQSPAAFTVG 1448
               STPA S+    S       SP   T G
Sbjct: 2883 TQHSTPALSSPHPSSRTTESPPSPGTTTPG 2912



 Score = 44.3 bits (103), Expect = 9e-04
 Identities = 105/471 (22%), Positives = 180/471 (38%), Gaps = 69/471 (14%)

Query: 1017 SSSAGFSFGTGVINSTPAPANTIVTS---ENKSSFNLGTIETKSASVAPFTCKTSEAKKE 1073
            +S+A  S  T V   TP P++T+ T+     +++  + T+ T   S  P T  TS     
Sbjct: 4785 TSTATKSTATSV---TPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTT 4841

Query: 1074 EMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVF 1133
            +   T+   S     P+S P  +  +   T         +T+   G  A    P   P  
Sbjct: 4842 KATTTRATSSTST--PSSTPGTTWILTELTT------AATTTAATGPTAT---PSSTPGT 4890

Query: 1134 SFGNSEQTKDENSSKSTFSFS-----------MTKPSEKESEQPAKATFAFGAQTSTTAD 1182
            ++  +E T    ++ ST S +           +T+PS   +      + A  + T  TA 
Sbjct: 4891 TWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAG 4950

Query: 1183 QGAAKPVFSFLNNSSSSSSTPATSAGGGI-FGSSTSSSNPPVATFVFGQSSNPVSSSAFG 1241
                    +     +SS +TP++S G      +  S++  P AT     S   + SS+ G
Sbjct: 4951 TPHVSTTAT-TPTVTSSKATPSSSPGTATALPALRSTATTPTAT-----SFTAIPSSSLG 5004

Query: 1242 NTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAG 1301
             T          +++ S+  T ++T +  TP      +S+  T  +     AT T++ A 
Sbjct: 5005 TT----------WTRLSQTTTPTATMSTATP------SSTPETVHTSTVLTATATTTGAT 5048

Query: 1302 SSFVFGTGPSAPSASPAFG-ANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPP 1360
             S       + PS++P      + PT   +   + P      S S  TAL P  + P   
Sbjct: 5049 GSV------ATPSSTPGTAHTTKVPTTTTTGFTATP------SSSPGTALTPPTTTPM-S 5095

Query: 1361 TFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGAN 1420
            T  T+ +SS P         +   + T   +S+A    +  T    T  + +   T  A 
Sbjct: 5096 TMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTAT-TTAAT 5154

Query: 1421 SSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSS--GTSFSGRKIKT 1469
             ST   S+ P G+       S  A  +   G    +SS  GT+ + + + T
Sbjct: 5155 GSTATLSSTP-GTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTT 5204



 Score = 40.8 bits (94), Expect = 0.010
 Identities = 63/278 (22%), Positives = 102/278 (36%), Gaps = 34/278 (12%)

Query: 1190 FSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSS-------SAFGN 1242
            +S   ++ ++SST   S+  G     T  +     T   G ++ P S+            
Sbjct: 2575 YSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTT 2634

Query: 1243 TAESSTSQSLLFSQDSKLAT-----------TSSTGTAVTPFVFGPGASSNNTTTSGFGF 1291
            TA + T  S   +  S   T           T+ T T+VTP    P +S   T T     
Sbjct: 2635 TATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPI---PSSSLGTTWTR---L 2688

Query: 1292 GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALF 1351
              TTT ++  S+    + P     S    A  T T      A+  + PG    +      
Sbjct: 2689 SQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTT 2748

Query: 1352 PTGSQPAPPTFGTVSSSSQPPVF-GQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNS 1410
             TG    P +  +  ++  PPV+     + +  GS  TP+S        +T        +
Sbjct: 2749 TTGFTATPSS--SPGTALTPPVWISTTTTPTTRGSTVTPSS-----IPGTTHTATVLTTT 2801

Query: 1411 PSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVG 1448
             + V T   + +TP++S Q SG+   P   +  A T G
Sbjct: 2802 TTTVAT--GSMATPSSSTQTSGTTHTPPVPNTMATTHG 2837



 Score = 38.1 bits (87), Expect = 0.063
 Identities = 79/338 (23%), Positives = 123/338 (36%), Gaps = 57/338 (16%)

Query: 1161 KESEQPAKATFAFGAQTSTTADQGAAKPVFS-----FLNNSSSSSSTPATSAGGGIFGSS 1215
            +E  Q  + +  FG         G  K  F+     F  N     STPATS+      SS
Sbjct: 3009 RELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTA--MPSS 3066

Query: 1216 TSSSN------PPVATFVFGQSSNPVSSSAFGNT---AESSTSQSLLFSQDSKLATTSST 1266
            T  +          AT      S    SS  G T    E ST+ ++     S    +S+ 
Sbjct: 3067 TPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQ 3126

Query: 1267 GTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSA------PSAS---- 1316
             TA TP V     +   T++    F +  T+++  +     T P+A      PS+S    
Sbjct: 3127 ATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTT 3186

Query: 1317 -PAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPP--- 1372
                    TPT   S       P    ++ +ST L  T +       G+V++ S  P   
Sbjct: 3187 WTRLSQTTTPTATMSTATPSSTPE---TVHTSTVLTTTATTTG--ATGSVATPSSTPGTA 3241

Query: 1373 -----------VFGQQPSQSAFGSGTTP----NSSSAFQFGSSTTNFNF--TNNSPSGVF 1415
                        F   PS S   + T P     +++    GS+ T  +   T ++P+ + 
Sbjct: 3242 HTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLT 3301

Query: 1416 T-----FGANSSTPAASAQPSGSGGFPFNQSPAAFTVG 1448
            T        + +TP++S Q SG+   P   +  A T G
Sbjct: 3302 TTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHG 3339



 Score = 35.0 bits (79), Expect = 0.54
 Identities = 37/161 (22%), Positives = 64/161 (39%), Gaps = 13/161 (8%)

Query: 479  ITSSSLPTFNFSSPEITTSSPSPINSSQALTNKVQMTSPSSTGSPMFKFSSPIVKSTEAN 538
            +T SS+P    ++  +TT++ +    S A  +    TS ++   P+   ++    +T   
Sbjct: 3930 VTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTA----TTHGR 3985

Query: 539  VLPPSSIGFTFSVPVAKTAELSGSSSTLEPIISSSAHHVTTVNSTNCKKTPPEDCEGPFR 598
             LPPSS     +   + T+ + G++   EP   +S H      ST    TP      P  
Sbjct: 3986 SLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTS-HTPAATTSTTQHSTPALSSPHP-- 4042

Query: 599  PAEILKEGSVLDILKSPGFASPKIDSVAAQPTATSPVVYTR 639
                       +   SPG  +P      ++ TAT+    TR
Sbjct: 4043 ------SSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTR 4077



 Score = 34.7 bits (78), Expect = 0.70
 Identities = 62/272 (22%), Positives = 100/272 (36%), Gaps = 47/272 (17%)

Query: 476  SLPITSSSLPTFNFSSPEITTSSPSPINSSQ---ALTNKVQMTSPSSTGSPMFKFSSPIV 532
            S P T+++LP    ++   T +S +PI SS      T   Q T+P++T S     S+P  
Sbjct: 2650 SSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPET 2709

Query: 533  KSTE-------------ANVLPPSS---IGFTFSVPVAKTAELSGSSST-----LEPIIS 571
              T               +V  PSS      T  VP   T   + + S+     L P + 
Sbjct: 2710 AHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVW 2769

Query: 572  SSAHHVTTVNSTNCKKTPPEDCEGPFRPAEILKEGSVLDILKSPGFASPKIDSVAAQPTA 631
             S    TT  +T      P    G    A +L   +    + +   A+P      +  T 
Sbjct: 2770 IS---TTTTPTTRGSTVTPSSIPGTTHTATVLT--TTTTTVATGSMATP------SSSTQ 2818

Query: 632  TSPVVYTRPAISSFSSSGIGFGESLKAGS------SWQCDT--CLLQNKVTDNKCIACQA 683
            TS   +T P  ++ +++    G SL   S      +W   T   L    +T+   +    
Sbjct: 2819 TSGTTHTPPVPNTMATT---HGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHT 2875

Query: 684  AKLSPRDTAKQT-GIETPNKSGKTTLSASGTG 714
               +   T   T  + +P+ S +TT S    G
Sbjct: 2876 LAATTGTTQHSTPALSSPHPSSRTTESPPSPG 2907



 Score = 34.7 bits (78), Expect = 0.70
 Identities = 170/830 (20%), Positives = 279/830 (33%), Gaps = 161/830 (19%)

Query: 691  TAKQTGIETPNKSGKTTLSASGTGFGDKFKPVIGTWDCDTCLVQNKPEAIKCVACETPKP 750
            T + T   T   +G T + +S  G     K +  T    T        + K  +  +P+ 
Sbjct: 3577 TEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTAT------SSKATSSSSPRT 3630

Query: 751  GTCVKRALTLTVVSESAETMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAED 810
             T +   LT T    +A + T   S    TTGTL   ++   P+ +   S    S+  E 
Sbjct: 3631 ATTLP-VLTSTATKSTATSFTPIPSFTLGTTGTLP--EQTTTPMATM--STIHPSSTPET 3685

Query: 811  NKCVSCMSEKPGSSVPASSSSTVPVSLPSGGSLGLEKFKKPEGSWDC-ELCLVQNKADST 869
                + ++ K  ++  A+SS + P S P               +W   EL        +T
Sbjct: 3686 THTSTVLTTK-ATTTRATSSMSTPSSTPGT-------------TWILTELTTAATTTAAT 3731

Query: 870  KCLACESAKPGT-----KSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNF 924
               A  S+ PGT     +       T  + S + ASS+       +++G  + LTST   
Sbjct: 3732 GPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASST------RATAGTLKVLTSTATT 3785

Query: 925  KFGDQGGFKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFG 984
                           S +    S G   + P                             
Sbjct: 3786 P----------TVISSRATPSSSPGTATALP----------------------------A 3807

Query: 985  LSSGLSNPVSLTPFQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANT--IVTS 1042
            L S  + P + +      S+LG    +  L ++++   +  T   +STP   +T  ++T+
Sbjct: 3808 LRSTATTPTATSVTAIPSSSLGTAWTR--LSQTTTPTATMSTATPSSTPETVHTSTVLTT 3865

Query: 1043 ENKSSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGR 1102
               ++   G++ T S++  P T  T++        T  GF+     P+S P  ++     
Sbjct: 3866 TTTTTRATGSVATPSST--PGTAHTTKVPT----TTTTGFT---ATPSSSPGTAL----- 3911

Query: 1103 TEEKQQEPV-TSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEK 1161
                   PV  ST+     +     P   P  +   +  T    ++ +  + SM  PS  
Sbjct: 3912 -----TPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLT---TTTTTVATGSMATPSS- 3962

Query: 1162 ESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGS------S 1215
             S Q +  T       +T    G + P      +S  +  T  TSA  GI G+      S
Sbjct: 3963 -STQTSGTTHTPPVPNTTATTHGRSLPP-----SSPHTVRTAWTSATSGILGTTHITEPS 4016

Query: 1216 TSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVF 1275
            T +S+ P AT    Q S P  SS   ++  + +  S   +       TS T    TP   
Sbjct: 4017 TVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKT 4076

Query: 1276 GPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQT----------- 1324
                   ++ TS       TT      ++      S P   P+ G   T           
Sbjct: 4077 RTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAV 4136

Query: 1325 ---PTFGQSQGASQPNPP--GFGSISSSTALFPT-------------------------- 1353
               P   + +  +QP  P    G +   +  F                            
Sbjct: 4137 CEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNY 4196

Query: 1354 GSQPA-PPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPS 1412
            G  P+ P T  T + SS P         +   + T    S+A    +  T +  T  S +
Sbjct: 4197 GHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTT 4256

Query: 1413 GVFTFGANSSTPAASAQPSGSGGFPFNQSPAAF-TVGSNGKNVFSSSGTS 1461
               T    S+  A+S Q   + G P   + A   TV S+    FSS GT+
Sbjct: 4257 ATVTVPTGSTATASSTQ--ATAGTPHVSTTATTPTVTSSKATPFSSPGTA 4304



 Score = 34.3 bits (77), Expect = 0.91
 Identities = 53/227 (23%), Positives = 79/227 (34%), Gaps = 14/227 (6%)

Query: 1232 SNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGF 1291
            S P +SS    ++   T+  +L    +   TT+STG+  TP    PG +      +    
Sbjct: 4703 STPATSSTAMPSSTPGTTW-ILTELTTTATTTASTGSTATP-SSTPGTAPPPKVLTSPAT 4760

Query: 1292 GATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALF 1351
              T TSS A SS    + P   +  P   +  T +   S     P P    S   +T   
Sbjct: 4761 TPTATSSKATSS----SSPRTATTLPVLTSTATKSTATS---VTPIP---SSTLGTTGTL 4810

Query: 1352 PTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSP 1411
            P  +     T  T+  SS P       S       TT  ++S+    SST    +     
Sbjct: 4811 PEQTTTPVATMSTIHPSSTPET--THTSTVLTTKATTTRATSSTSTPSSTPGTTWILTEL 4868

Query: 1412 SGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSS 1458
            +   T  A +   A  +   G+       +  A T  S G     SS
Sbjct: 4869 TTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSS 4915


>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
          Length = 587

 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 118/499 (23%), Positives = 189/499 (37%), Gaps = 89/499 (17%)

Query: 1016 KSSSAGFSFGTGVINSTPAPANTIV---TSENKSSFNLGTIETKSASVAPFTCKTSEAKK 1072
            + S+   S  T  I+S P+  + +V   TS + S  +  T     +S      + S A  
Sbjct: 14   EESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASH 73

Query: 1073 EEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPV 1132
                AT      G +   +  + SV +LG   E    P++S S+         E    P 
Sbjct: 74   SSQDAT------GTIVLPARSTTSV-LLG---ESTTSPISSGSM---------ETTALP- 113

Query: 1133 FSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSF 1192
                 S  T   +   +TF  S   P+   S  PA  T +  ++ STT+    ++P    
Sbjct: 114  ----GSTTTPGLSEKSTTFHSSPRSPATTLS--PASTTSSGVSEESTTSH---SRP---- 160

Query: 1193 LNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSL 1252
               S+ +++ P ++   G+   ST+S + P +T     +  P S++  G + ES+TS S 
Sbjct: 161  --GSTHTTAFPDSTTTPGLSRHSTTSHSSPGST---DTTLLPASTTTSGPSQESTTSHSS 215

Query: 1253 LFSQDSKLATTSST----GTAVTPFVFGPGASS-----NNTTTSGFGFGATTTSSSAGS- 1302
              S D+ L+  S+T    G   T F   PG++      ++TT+SG    +T   SS GS 
Sbjct: 216  PGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP 275

Query: 1303 ----SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSI-------------S 1345
                S    T P     S AF  +   T       + P+PP   +              S
Sbjct: 276  RTTLSPASSTSPGLQGESTAFQTHPASTH------TTPSPPSTATAPVEESTTYHRSPGS 329

Query: 1346 SSTALFPTGS------------QPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSS 1393
            + T  FP  S              +P   GT  SS+     G     S   S + P S+ 
Sbjct: 330  TPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGVSEESST--SHSQPGSTH 387

Query: 1394 AFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKN 1453
               F  STT    +    +   + G+  +T   +  P G+   P   S    +  S+   
Sbjct: 388  TTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSSTPT 447

Query: 1454 V-FSSSGTSFSGRKIKTAV 1471
              FS+S T+    +  T V
Sbjct: 448  THFSASSTTLGRSEESTTV 466



 Score = 54.7 bits (130), Expect = 7e-07
 Identities = 106/468 (22%), Positives = 175/468 (37%), Gaps = 53/468 (11%)

Query: 1010 KKEELPKSSSAGFSFGTGVINSTPAPANTIVT--SENKSSFNLGTIETKSASVAPFTCKT 1067
            + EE   S S+  + GT V+   PA + T V       S  + G++ET +   +  T   
Sbjct: 65   RSEESTASHSSQDATGTIVL---PARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGL 121

Query: 1068 SEAK-----KEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKA 1122
            SE           PAT        + PAS  S+ V     T   +  P ++ +  F    
Sbjct: 122  SEKSTTFHSSPRSPAT-------TLSPASTTSSGVSEESTTSHSR--PGSTHTTAFPDST 172

Query: 1123 DNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTAD 1182
                       S  +   T       ST +   ++ S      P     A    ++T   
Sbjct: 173  TTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALS 232

Query: 1183 QGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSST---SSSNPPVATFVFGQSSNPVSSSA 1239
             G     F     S+ ++  P ++   GI  +ST   SS+  P  T       +P SS++
Sbjct: 233  FGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL------SPASSTS 286

Query: 1240 FGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPG--ASSNNTTTSGFGFGATTTS 1297
             G   ES+  Q+      S   T S   TA  P         S  +T T+ F   ++TTS
Sbjct: 287  PGLQGESTAFQT---HPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFP-ASSTTS 342

Query: 1298 SSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQP 1357
              +  S +F + P A   +P+  A+ T +    + ++  + PG    S+ T  FP  +  
Sbjct: 343  GHSEKSTIFHSSPDASGTTPS-SAHSTTSGVSEESSTSHSQPG----STHTTAFPDST-- 395

Query: 1358 APPTFGTVSSSSQPPV---FGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGV 1414
                  T S  SQ P      Q  +++   +  +P  ++A     STT  +  +++P+  
Sbjct: 396  ------TTSGLSQEPTTSHSSQGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSSTPT-- 447

Query: 1415 FTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSF 1462
              F A+S+T   S + +     P +    A   GS      S   T+F
Sbjct: 448  THFSASSTTLGRSEESTTVHSSPGSTETTALP-GSTTTAGLSEKSTTF 494



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 122/558 (21%), Positives = 200/558 (35%), Gaps = 64/558 (11%)

Query: 815  SCMSEKPGS--SVPASSSST-VPVSLPSGGSLGLEKFKKPEGSWDCELCLVQNKADSTKC 871
            S + E+P S  S P S+++T  P S  + G    E+      S D    +V     +T  
Sbjct: 35   SALVEEPTSYHSSPGSTATTHFPDSSTTSGRS--EESTASHSSQDATGTIVLPARSTTSV 92

Query: 872  LACESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGG 931
            L  ES      SG         S+ +   S       SS   P+ TL+       G    
Sbjct: 93   LLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSG---- 148

Query: 932  FKIGVSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSN 991
                VS +S + +        S+P           +    + + S   +   G +     
Sbjct: 149  ----VSEESTTSH--------SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLL 196

Query: 992  PVSLT---PFQFGVSNLGQEEKKEE-LPKSSSAGFSFG--TGVINSTPAPANTIVTSENK 1045
            P S T   P Q   ++       +  L   S+   SFG  +   +S+P   +T +  ++ 
Sbjct: 197  PASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDST 256

Query: 1046 SSFNLGTIETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEE 1105
            +S  +    T+  S       T        P  +G  +     PAS           T  
Sbjct: 257  TSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAS-----------THT 305

Query: 1106 KQQEPVTSTSLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQ 1165
                P T+T+ V      +  P   P   F  S  T   +S KST   S    S      
Sbjct: 306  TPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSG-HSEKSTIFHSSPDASGTTPSS 364

Query: 1166 PAKATFAFGAQTSTTADQGAAKPVFSFLNNSSSS--SSTPATS--AGGGIFGSSTSSSNP 1221
                T     ++ST+  Q  +    +F +++++S  S  P TS  + G    +  ++ +P
Sbjct: 365  AHSTTSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSP 424

Query: 1222 PVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASS 1281
            P      G ++ PV  S   ++  SST  +  FS  S     S   T V        +S 
Sbjct: 425  P------GTTAAPVEVSTTYHSRPSSTPTTH-FSASSTTLGRSEESTTVH-------SSP 470

Query: 1282 NNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGF 1341
             +T T+    G+TTT+  +  S  F + P +P  + +  A+ T +    +  +  + PG 
Sbjct: 471  GSTETTALP-GSTTTAGLSEKSTTFYSSPRSPDTTLS-PASTTSSGVSEESTTSHSRPG- 527

Query: 1342 GSISSSTALFPTGSQPAP 1359
               S+ T  FP GS   P
Sbjct: 528  ---STHTTAFP-GSTTMP 541



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 82/305 (26%), Positives = 124/305 (40%), Gaps = 58/305 (19%)

Query: 1176 QTSTTADQGAAKPVFSFLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPV 1235
            ++ TT+ +G      S  + + + SS P+T++      +S  SS    AT  F     P 
Sbjct: 5    ESDTTSGRGEESTT-SHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHF-----PD 58

Query: 1236 SSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATT 1295
            SS+  G + ES+ S S   SQD+       TGT V P           +TTS    G+  
Sbjct: 59   SSTTSGRSEESTASHS---SQDA-------TGTIVLPARSTTSVLLGESTTSPISSGSME 108

Query: 1296 TSSSAGS---------SFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISS 1346
            T++  GS         S  F + P +P A+    A+ T +    +  +  + PG    S+
Sbjct: 109  TTALPGSTTTPGLSEKSTTFHSSPRSP-ATTLSPASTTSSGVSEESTTSHSRPG----ST 163

Query: 1347 STALFP------------TGSQPAPPTFGT----VSSSSQPPVFGQQPSQSAFGSGTT-- 1388
             T  FP            T S  +P +  T     S+++  P      S S+ GS  T  
Sbjct: 164  HTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTAL 223

Query: 1389 -PNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPA-----ASAQPSGSGGFP-FNQS 1441
             P S++A  FG  +T F   ++SP    T     ST +     AS +   S G P    S
Sbjct: 224  SPGSTTALSFGQESTTF---HSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLS 280

Query: 1442 PAAFT 1446
            PA+ T
Sbjct: 281  PASST 285



 Score = 44.3 bits (103), Expect = 9e-04
 Identities = 128/562 (22%), Positives = 211/562 (37%), Gaps = 59/562 (10%)

Query: 769  TMTASSSSCTVTTGTLGFGDKFKRPIGSWECSVCCVSNNAEDNKCVSCMSEKPGSSVPAS 828
            T + SS++ T+++         + P           + +  D+   S  SE+  +S  +S
Sbjct: 17   TTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTAS-HSS 75

Query: 829  SSSTVPVSLPSGGSLGL---EKFKKPEGSWDCELCLVQNKADSTKCLACESAKPGTKSGF 885
              +T  + LP+  +  +   E    P  S   E          T  L   +  PG     
Sbjct: 76   QDATGTIVLPARSTTSVLLGESTTSPISSGSME----------TTALPGSTTTPGLSEKS 125

Query: 886  KGFDTS--SSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSI 943
              F +S  S ++  + +S+   GVS  S+       ST    F D      G+S  S + 
Sbjct: 126  TTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTP-GLSRHS-TT 183

Query: 944  NPMSEGFKFSK--PIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFG 1001
            +  S G   +   P      G S ES        S +     G ++ LS     T F   
Sbjct: 184  SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFH-- 241

Query: 1002 VSNLGQEEKKEELPKSSSAGF-SFGTGVINSTPAPANTIVTSENKSSFNLG---TIETKS 1057
             S+ G          ++S+G     T V +ST +P  T+  + + S    G     +T  
Sbjct: 242  -SSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHP 300

Query: 1058 ASV--APFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTS 1115
            AS    P    T+ A  EE  +T    S G+      P++S    G +E+       ST 
Sbjct: 301  ASTHTTPSPPSTATAPVEE--STTYHRSPGSTPTTHFPASST-TSGHSEK-------STI 350

Query: 1116 LVFGKKADNEEPKCQPVFSFGNSEQTKDENS---SKSTFSFSMTKPSEKESEQPAKATFA 1172
                  A    P      + G SE++   +S   S  T +F  +  +   S++P  +  +
Sbjct: 351  FHSSPDASGTTPSSAHSTTSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSS 410

Query: 1173 FGA-----QTSTTADQGAAKPVFSFLNNSSSSSSTPAT--SAGGGIFGSSTSSSNPPVAT 1225
             G+      T+ +     A PV       S  SSTP T  SA     G S  S+    + 
Sbjct: 411  QGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP 470

Query: 1226 FVFGQSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTT 1285
                 ++ P S++  G + +S+T  S   S D+ L+  S+T + V          S  +T
Sbjct: 471  GSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGV----------SEEST 520

Query: 1286 TSGFGFGATTTSSSAGSSFVFG 1307
            TS    G+T T++  GS+ + G
Sbjct: 521  TSHSRPGSTHTTAFPGSTTMPG 542



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 101/437 (23%), Positives = 157/437 (35%), Gaps = 58/437 (13%)

Query: 94  SNITDGRITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHRSHLNFSMLESPALHCQPSTS 153
           ++ T   ++ E   S++   ST +TA  +PD  T P L R                 ST+
Sbjct: 142 ASTTSSGVSEESTTSHSRPGSTHTTA--FPDSTTTPGLSRH----------------STT 183

Query: 154 SAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRASDKDITVSKNTSLPPLWSPEAE 213
           S    GS+  +L+     ST+       STTS  S  ++D  ++    T+L         
Sbjct: 184 SHSSPGSTDTTLLPA---STTTSGPSQESTTSHSSPGSTDTALSPGSTTAL--------- 231

Query: 214 RSHSLSQHTATSSKKPAFNLSAFGTLSP-SLGNSSILKTSQLGDSPFYPGKTTYGGAAAA 272
              S  Q + T    P    S   TL P S  +S I++ S    S     +TT   A++ 
Sbjct: 232 ---SFGQESTTFHSSPG---STHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASST 285

Query: 273 VRQSKLRNTPYQA-PVRRQMKAKQLSAQSYGVTSSTA-RRILQSLEKMSSPLADAKRIPS 330
               +  +T +Q  P          S  +  V  ST   R   S      P +      S
Sbjct: 286 SPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHS 345

Query: 331 IVSSPLNSPLDRSGIDITDFQAKREKVDSQYPPVQRLMTPKPVSIATNRSVYFKPSLTPS 390
             S+  +S  D SG   +   +    V  +          +P S  T     F  S T S
Sbjct: 346 EKSTIFHSSPDASGTTPSSAHSTTSGVSEE----SSTSHSQPGSTHTTA---FPDSTTTS 398

Query: 391 GEFRKTNQRIDNKCSTGYEKNMTP---GQNREQRESGFSYPN--FSLPAANGLSSGVGGG 445
           G  ++      ++ ST    + TP   G      E   +Y +   S P  +  +S    G
Sbjct: 399 GLSQEPTTSHSSQGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLG 458

Query: 446 GGKMRRERTRFVASKPLEEEEMEVPVLPKISLPITSSSLPTFNFSSPEITTSSPSPINSS 505
               R E +  V S P      E   LP  +     S   T  +SSP    ++ SP +++
Sbjct: 459 ----RSEESTTVHSSP---GSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTT 511

Query: 506 QALTNKVQMTSPSSTGS 522
            +  ++   TS S  GS
Sbjct: 512 SSGVSEESTTSHSRPGS 528


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.123    0.350 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,421,546
Number of Sequences: 37866
Number of extensions: 3266092
Number of successful extensions: 22627
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 113
Number of HSP's successfully gapped in prelim test: 584
Number of HSP's that attempted gapping in prelim test: 13909
Number of HSP's gapped (non-prelim): 4985
length of query: 1475
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1360
effective length of database: 13,892,928
effective search space: 18894382080
effective search space used: 18894382080
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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