BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|119829187 alpha 1 type XVII collagen [Homo sapiens] (1497 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 3103 0.0 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 508 e-143 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 499 e-140 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 498 e-140 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 496 e-140 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 495 e-139 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 494 e-139 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 493 e-139 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 493 e-139 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 493 e-139 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 493 e-139 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 492 e-138 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 488 e-137 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 488 e-137 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 488 e-137 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 487 e-137 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 487 e-137 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 487 e-137 gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 473 e-133 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 468 e-131 gi|48762934 alpha 2 type I collagen [Homo sapiens] 454 e-127 gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 453 e-127 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 453 e-127 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 453 e-127 gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 453 e-127 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 452 e-126 gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 449 e-126 gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 437 e-122 gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 435 e-121 gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens] 435 e-121 >gi|119829187 alpha 1 type XVII collagen [Homo sapiens] Length = 1497 Score = 3103 bits (8045), Expect = 0.0 Identities = 1497/1497 (100%), Positives = 1497/1497 (100%) Query: 1 MDVTKKNKRDGTEVTERIVTETVTTRLTSLPPKGGTSNGYAKTASLGGGSRLEKQSLTHG 60 MDVTKKNKRDGTEVTERIVTETVTTRLTSLPPKGGTSNGYAKTASLGGGSRLEKQSLTHG Sbjct: 1 MDVTKKNKRDGTEVTERIVTETVTTRLTSLPPKGGTSNGYAKTASLGGGSRLEKQSLTHG 60 Query: 61 SSGYINSTGSTRGHASTSSYRRAHSPASTLPNSPGSTFERKTHVTRHAYEGSSSGNSSPE 120 SSGYINSTGSTRGHASTSSYRRAHSPASTLPNSPGSTFERKTHVTRHAYEGSSSGNSSPE Sbjct: 61 SSGYINSTGSTRGHASTSSYRRAHSPASTLPNSPGSTFERKTHVTRHAYEGSSSGNSSPE 120 Query: 121 YPRKEFASSSTRGRSQTRESEIRVRLQSASPSTRWTELDDVKRLLKGSRSASVSPTRNSS 180 YPRKEFASSSTRGRSQTRESEIRVRLQSASPSTRWTELDDVKRLLKGSRSASVSPTRNSS Sbjct: 121 YPRKEFASSSTRGRSQTRESEIRVRLQSASPSTRWTELDDVKRLLKGSRSASVSPTRNSS 180 Query: 181 NTLPIPKKGTVETKIVTASSQSVSGTYDATILDANLPSHVWSSTLPAGSSMGTYHNNMTT 240 NTLPIPKKGTVETKIVTASSQSVSGTYDATILDANLPSHVWSSTLPAGSSMGTYHNNMTT Sbjct: 181 NTLPIPKKGTVETKIVTASSQSVSGTYDATILDANLPSHVWSSTLPAGSSMGTYHNNMTT 240 Query: 241 QSSSLLNTNAYSAGSVFGVPNNMASCSPTLHPGLSTSSSVFGMQNNLAPSLTTLSHGTTT 300 QSSSLLNTNAYSAGSVFGVPNNMASCSPTLHPGLSTSSSVFGMQNNLAPSLTTLSHGTTT Sbjct: 241 QSSSLLNTNAYSAGSVFGVPNNMASCSPTLHPGLSTSSSVFGMQNNLAPSLTTLSHGTTT 300 Query: 301 TSTAYGVKKNMPQSPAAVNTGVSTSAACTTSVQSDDLLHKDCKFLILEKDNTPAKKEMEL 360 TSTAYGVKKNMPQSPAAVNTGVSTSAACTTSVQSDDLLHKDCKFLILEKDNTPAKKEMEL Sbjct: 301 TSTAYGVKKNMPQSPAAVNTGVSTSAACTTSVQSDDLLHKDCKFLILEKDNTPAKKEMEL 360 Query: 361 LIMTKDSGKVFTASPASIAATSFSEDTLKKEKQAAYNADSGLKAEANGDLKTVSTKGKTT 420 LIMTKDSGKVFTASPASIAATSFSEDTLKKEKQAAYNADSGLKAEANGDLKTVSTKGKTT Sbjct: 361 LIMTKDSGKVFTASPASIAATSFSEDTLKKEKQAAYNADSGLKAEANGDLKTVSTKGKTT 420 Query: 421 TADIHSYGSSGGGGSGGGGGVGGAGGGPWGPAPAWCPCGSCCSWWKWLLGLLLTWLLLLG 480 TADIHSYGSSGGGGSGGGGGVGGAGGGPWGPAPAWCPCGSCCSWWKWLLGLLLTWLLLLG Sbjct: 421 TADIHSYGSSGGGGSGGGGGVGGAGGGPWGPAPAWCPCGSCCSWWKWLLGLLLTWLLLLG 480 Query: 481 LLFGLIALAEEVRKLKARVDELERIRRSILPYGDSMDRIEKDRLQGMAPAAGADLDKIGL 540 LLFGLIALAEEVRKLKARVDELERIRRSILPYGDSMDRIEKDRLQGMAPAAGADLDKIGL Sbjct: 481 LLFGLIALAEEVRKLKARVDELERIRRSILPYGDSMDRIEKDRLQGMAPAAGADLDKIGL 540 Query: 541 HSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPG 600 HSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPG Sbjct: 541 HSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPG 600 Query: 601 PQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGV 660 PQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGV Sbjct: 601 PQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGV 660 Query: 661 PGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGL 720 PGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGL Sbjct: 661 PGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGL 720 Query: 721 TGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGL 780 TGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGL Sbjct: 721 TGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGL 780 Query: 781 TGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGP 840 TGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGP Sbjct: 781 TGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGP 840 Query: 841 AGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNS 900 AGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNS Sbjct: 841 AGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNS 900 Query: 901 ETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQG 960 ETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQG Sbjct: 901 ETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQG 960 Query: 961 PKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISE 1020 PKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISE Sbjct: 961 PKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISE 1020 Query: 1021 YMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSS 1080 YMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSS Sbjct: 1021 YMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSS 1080 Query: 1081 SISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSS 1140 SISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSS Sbjct: 1081 SISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSS 1140 Query: 1141 SGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVED 1200 SGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVED Sbjct: 1141 SGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVED 1200 Query: 1201 LSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVR 1260 LSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVR Sbjct: 1201 LSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVR 1260 Query: 1261 SFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGS 1320 SFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGS Sbjct: 1261 SFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGS 1320 Query: 1321 LGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRV 1380 LGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRV Sbjct: 1321 LGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRV 1380 Query: 1381 SESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPP 1440 SESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPP Sbjct: 1381 SESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPP 1440 Query: 1441 GQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 GQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP Sbjct: 1441 GQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 508 bits (1307), Expect = e-143 Identities = 359/964 (37%), Positives = 416/964 (43%), Gaps = 197/964 (20%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGR 625 RG PG +G +G G G RG G PG PGP+G G G G G+ G G GP G RG Sbjct: 338 RGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGP 397 Query: 626 EGPMGPRGEAGPPG----SGEKGERGAAGEPGPHGPPGVPGSVGPKGSS---GSPGPQGP 678 EGP G RGE GPPG G G G G PG GP G PG+ GP GS+ GSPGPQG Sbjct: 398 EGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGS 457 Query: 679 PGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQ------GEKGPRGLTGEPGMRGLPGA 732 GP G++G G+ G+PG KG+ GP G PGP G Q GE+G RG G+PG G PG Sbjct: 458 TGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGP 517 Query: 733 VGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGT 792 VGE GA G G G DG GP+G QG G G GP G GDPG+PG G G +GL G Sbjct: 518 VGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGN 577 Query: 793 P------------GRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGP 840 P G PG G PG PG I + PG G PG G G PG PG Sbjct: 578 PGVQGPEGKLGPLGAPGEDGRPGPPGSI------GIRGQPGSMGLPGPKGSSGDPGKPGE 631 Query: 841 AGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPG----EGLPGPPGPPGSF 896 AG AG+PG + G GP GP GPPG + G G +GPPG +GLPGPPGPPG Sbjct: 632 AGNAGVPGQRGAPGKDGEVGPSGPVGPPG--LAGERGEQGPPGPTGFQGLPGPPGPPGEG 689 Query: 897 LSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPP 956 + + G PG GP GP+G++G PG RG G GLPG GP GP Sbjct: 690 GKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGG------HGPDGPK 743 Query: 957 GPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQ 1016 G GP G GD G PG G+P G G PGP G G I G E Sbjct: 744 GSPGPSGTPGDTGPPGLQGMPG------------ERGIAGTPGPKGDRGGIGEKGAE--- 788 Query: 1017 YISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVS 1076 +D R G+ GP GPPGP GP TGE + Sbjct: 789 ---GTAGNDGAR----GLPGPLGPPGPAGP----TGEKGE-------------------- 817 Query: 1077 LFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILS 1136 GPRG GPPG+ G+ SR Sbjct: 818 ----------------------------PGPRGLVGPPGSRGNP----------GSR--G 837 Query: 1137 YMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEF----RGIVGPPGPPGPPGIPGNV 1192 +G ++G GP GP G PG E +G +G+ G PGP GP G+PG Sbjct: 838 ENGPTG-AVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPG-- 894 Query: 1193 WSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELIS 1252 ++ G + PG G GPPGP G PG +G L E R + S Sbjct: 895 -----LKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGS 949 Query: 1253 YLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMS 1312 + D GPPG PG +G PG+ D ++ G M Sbjct: 950 HGRVGDRGP--AGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMP 1007 Query: 1313 TGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMY--AGNGGLLGADFAGD 1370 G AG+ G G G A GD+GP G +GP G G E G AGN G G D A Sbjct: 1008 GLPGPAGTPGKVGPTG-ATGDKGPPG-PVGPPGSNGPVGEPGPEGPAGNDGTPGRDGA-- 1063 Query: 1371 LDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFF 1430 V E R GP G PG QG PG Sbjct: 1064 ---------VGERGDRGD---------PGPAGLPGSQGAPG------------------- 1086 Query: 1431 QTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGH------PGPPGPRGHKGEKGDKGDQVY 1484 GP G G+ G G G RGP GPPG PGP GPRG KG+ GD+GD+ Sbjct: 1087 -----TPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQ 1141 Query: 1485 AGRR 1488 G R Sbjct: 1142 KGHR 1145 Score = 486 bits (1250), Expect = e-137 Identities = 362/1018 (35%), Positives = 435/1018 (42%), Gaps = 186/1018 (18%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGRE 626 G+PG G GSPG +G G PG PG+ G GH G +GPKG+ G+ G G GP G G Sbjct: 273 GNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAM 332 Query: 627 GPMGPRG------EAGPPGS-GEKGERGAAGEPGPHGPPGVPGS------------VGPK 667 GP+GPRG GP G+ G++G G G+PGP GP G+PGS GP Sbjct: 333 GPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPT 392 Query: 668 GSSGSPGPQG------PPGPVGLQGLRGEVGLPGVKGDKGPMG------------PPGPK 709 G+ G GPQG PPGPVG GL G +G G G KGP G PPG Sbjct: 393 GARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSP 452 Query: 710 GDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGA---------MGPAGPDGHQGPRGEQGLT 760 G QG GP+G+ G+PG G+PG GE G KG +GP G +G +GPRG+ G Sbjct: 453 GPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTV 512 Query: 761 GMPGI---RGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSML 817 G PG RG PG G PG GL GP+G QG G G G KG G PG+ Sbjct: 513 GPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGR---------- 562 Query: 818 TVPGPPGPPGAMGPPGPPGAPGPAG---PAGLPGHQEVLNLQGPPGPPGPRGPPGP-SIP 873 PG PG PGA G G PG GP G P G PG GPPG G RG PG +P Sbjct: 563 --PGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGED---GRPGPPGSIGIRGQPGSMGLP 617 Query: 874 GPPGPRGPPGE-------GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPR 926 GP G G PG+ G+PG G PG + E SGP GPPG G +G+QGPPGP Sbjct: 618 GPKGSSGDPGKPGEAGNAGVPGQRGAPGK---DGEVGPSGPVGPPGLAGERGEQGPPGPT 674 Query: 927 GHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSS 986 G QG G PG G + G PG GP GP+G++G+PG G GI P E G + Sbjct: 675 GFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMA 734 Query: 987 STMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGP 1046 GP G PGP G PG G L G+ G G G PGP Sbjct: 735 GGHGPDGPKGSPGPSGTPGDTGPPG-------------------LQGMPGERGIAGTPGP 775 Query: 1047 VTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMG 1106 G I + D R L G Sbjct: 776 KGDRGG-----------------------------IGEKGAEGTAGNDGARG-----LPG 801 Query: 1107 PRGPPGPPGASGDGS------LLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTS 1160 P GPPGP G +G+ L+ + + +G ++G GP GP G PG Sbjct: 802 PLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTG-AVGFAGPQGPDGQPGVK 860 Query: 1161 YEELLSLLRGSEF----RGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGP 1216 E +G +G+ G PGP GP G+PG ++ G + PG Sbjct: 861 GEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPG-------LKGGRGTQGPPGATGFPGS 913 Query: 1217 PGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPP 1276 G GPPGP G PG +G L E R + S+ D GPPG PG +G P Sbjct: 914 AGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGP--AGPPGGPGDKGDP 971 Query: 1277 GDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGP 1336 G+ D ++ G M G AG+ G G G A GD+GP Sbjct: 972 GEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTG-ATGDKGP 1030 Query: 1337 YGTDIGPGGGYGAAAEGGMY--AGNGGLLGADFA----GDL-DYNELAVRVSESMQ-RQG 1388 G +GP G G E G AGN G G D A GD D + S+ G Sbjct: 1031 PGP-VGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPG 1089 Query: 1389 LLQGMAYTVQ----------GPPGQ------PGPQGPPGISKVFSAYSNVTADLMDFFQT 1432 + Q GPPG+ PGPQGP G + F Sbjct: 1090 PVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTG 1149 Query: 1433 YGAIQGPPGQKGEMGT---PGPKGDRGPAGP------PGHPGPPGPRGHKGEKGDKGD 1481 + GPPG GE G+ PGP G RGP GP G+PGP GP G G +G G+ Sbjct: 1150 LQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGE 1207 Score = 443 bits (1140), Expect = e-124 Identities = 353/1004 (35%), Positives = 415/1004 (41%), Gaps = 203/1004 (20%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 +RG PGP G GS GP+G+RG G PG GPQG G+ G G PG GP G Sbjct: 127 IRGRPGPAGPPGSQGPRGERGPKGRPG------PRGPQGIDGEPGVPGQPGAPGPPGHPS 180 Query: 625 REGPMG------------------------PRGEAGPPG-SGEKGERGAAGEPGPHGPPG 659 GP G G GP G G +G +G G GP GPPG Sbjct: 181 HPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPG 240 Query: 660 VPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRG 719 PG GP G GS GP+GPPG G G G G P G+ G G PG +G G G G Sbjct: 241 EPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNP---GEVGFAGSPGARGFPGAPGLPG 297 Query: 720 LTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGK-- 777 L G G +GL G GE GA G+ G AGP G G G G GMPG RG GP G PG+ Sbjct: 298 LKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRG 357 Query: 778 ----PGLTGPQGPQGLPGT---PGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMG 830 PG GP GP G+PG+ PG PG+KGE G G GPPGP G+ G Sbjct: 358 AHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPG 417 Query: 831 PP---GPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGP---------RGPPG-PSIPGPPG 877 P G G PG GP G PG GPPG PGP RG PG P +PG G Sbjct: 418 LPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKG 477 Query: 878 PRGPPGE----GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQG 933 GP GE G+ GP GPPG + G PG GPPGP G++G PG RG G G Sbjct: 478 EAGPKGEPGPHGIQGPIGPPG---EEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDG 534 Query: 934 LPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGD------PGVPGALGIPSGPSEGGSSS 987 LPG QG GP G GPKG +GD PG+PGA G+ P G Sbjct: 535 LPG---------PKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEG 585 Query: 988 TMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPV 1047 + G PG G PGPPGSI G++G PG G PGP Sbjct: 586 KLGPLGAPGEDGRPGPPGSI-------------------------GIRGQPGSMGLPGPK 620 Query: 1048 TTITGETFDYSELASHVVSYLR-TSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMG 1106 + +G+ E + V R G + S LA + + G Sbjct: 621 GS-SGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGE----------QG 669 Query: 1107 PRGP------PGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTS 1160 P GP PGPPG G+G + + G G PG G PG+ G Sbjct: 670 PPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRG-ERGNPGERGEPGITGLP 728 Query: 1161 YEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPP 1220 E+ ++ G + GP G PGP G PG+ GL +PG G Sbjct: 729 GEKGMAGGHGPD-----GPKGSPGPSGTPGDT-------------GPPGLQGMPGERGIA 770 Query: 1221 GPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGP---QGPPG 1277 G PGP+G G G +D R L P +GPPGP GP +G PG Sbjct: 771 GTPGPKGDRGGIGEKGAEGTAGNDGARG-----LPGP------LGPPGPAGPTGEKGEPG 819 Query: 1278 DSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPY 1337 L+ SRG+ S RG + + G G G G GE G+ G Sbjct: 820 PRGLVGPPG--SRGNPGS-------RGENGPTGAVGFAGPQGPDGQPGVKGE-PGEPGQK 869 Query: 1338 GTDIGPGGGYGAAAEGGMYAGNG--GLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAY 1395 G D G G G A G + NG GL G R ++ G A Sbjct: 870 G-DAGSPGPQGLAGSPGPHGPNGVPGLKGG-------------RGTQGPPGATGFPGSAG 915 Query: 1396 TV--QGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKG 1453 V GP G PGP GP G +GPPG +G+ G+ G G Sbjct: 916 RVGPPGPAGAPGPAGPLG---------------------EPGKEGPPGLRGDPGSHGRVG 954 Query: 1454 DRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 DRGPAGPPG PG G G G+ G G AG +R I P Sbjct: 955 DRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMP 998 Score = 419 bits (1078), Expect = e-117 Identities = 275/711 (38%), Positives = 323/711 (45%), Gaps = 171/711 (24%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPG------IPGPLGHPGPQGPKGQKGSVGDPGMEGPM 620 G GP G +G PG G+RG G PG +PGP G PG G G +G GDPG GP+ Sbjct: 648 GEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPL 707 Query: 621 GQRGREGPMGPRGEAGPPG-------------SGEKGERGAAGEPGPHGPPGVPGSVGPK 667 G RG G G RGE G G G KG G +G PG GPPG+ G G + Sbjct: 708 GPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGER 767 Query: 668 GSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKG---PRGLTGEP 724 G +G+PGP+G G +G +G G G G +G GP+GPPGP G GEKG PRGL G P Sbjct: 768 GIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPP 827 Query: 725 GMRGLPGAVGEPGAKGAMG---PAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLT 781 G RG PG+ GE G GA+G P GPDG G +GE G G G G PGP G G PG Sbjct: 828 GSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPG-- 885 Query: 782 GPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPA 841 P GP G+PG G G +G PGA G PG G +GPPGP GAPGPA Sbjct: 886 -PHGPNGVPGLKGGRGTQGPPGATGF---------------PGSAGRVGPPGPAGAPGPA 929 Query: 842 GPAGLPGHQEVLNLQGPPGPPG---PRGPPGPSIPGPPGPRGPPGE-GLPGPPGPPGSFL 897 GP G PG + L+G PG G RGP GP PG PG +G PGE G PGP GPPG Sbjct: 930 GPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGP--PGGPGDKGDPGEDGQPGPDGPPGPAG 987 Query: 898 SNSETFLSGPPGP------PGPPGPKGDQGPPGPRGHQGEQGLPG-FSTSGSSSFGLNLQ 950 + + + G PG PG PGP G G GP G G++G PG GS+ Sbjct: 988 TTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSN------- 1040 Query: 951 GPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSS 1010 GP G PGP+GP G+ G PG GA+G + G + G PG PGP G PG Sbjct: 1041 GPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQR 1100 Query: 1011 GQEIQQYISEYMQSDSIRSYLSGVQGPPGP------PGPPGPVTTITGETFDYSELASHV 1064 G + G GPPG PGP GP G+ D+ + Sbjct: 1101 GDPGSR----------------GPIGPPGRAGKRGLPGPQGP----RGDKGDHGD----- 1135 Query: 1065 VSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLS 1124 R D Q + G +G PGPPG +G+ Sbjct: 1136 ----------------------------RGDRGQKGHRGFTGLQGLPGPPGPNGEQG--- 1164 Query: 1125 LDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPG 1184 S G+PGP GP G PG + S G GP GP G Sbjct: 1165 -------------------SAGIPGPFGPRGPPGP--------VGPSGKEGNPGPLGPIG 1197 Query: 1185 PPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGAL 1235 PPG+ G+V + GP GPPG PGP GPPG G L Sbjct: 1198 PPGVRGSVGEA-------------------GPEGPPGEPGPPGPPGPPGHL 1229 Score = 410 bits (1055), Expect = e-114 Identities = 297/822 (36%), Positives = 351/822 (42%), Gaps = 169/822 (20%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 +RG PG G G G G +G PG GI GP+G PG +G +G +G G G GP+G+RG Sbjct: 463 IRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERG 522 Query: 625 REGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGP------PGVPGSVGPKGSSGSPGPQG 677 G G G G PG G +GERG G GP G PG PG G +G +G+PG QG Sbjct: 523 APGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQG 582 Query: 678 PPGPVGLQGLRGEVGLP------GVKGDKGPMGPPGPK---GDQGEKGPRGLTGEPGMRG 728 P G +G G GE G P G++G G MG PGPK GD G+ G G G PG RG Sbjct: 583 PEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRG 642 Query: 729 LPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGD---------PGKPG 779 PG GE G G +GP G G +G +G G TG G+ GPPGP G+ PG PG Sbjct: 643 APGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPG 702 Query: 780 LTGPQGPQGLPGTP---GRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPG 836 GP GP+G G P G PGI G PG G PGP G PG GPPG G Sbjct: 703 AVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQG 762 Query: 837 APGPAGPAGLP------------------GHQEVLNLQGPPGPPGPRGP------PGP-S 871 PG G AG P G+ L GP GPPGP GP PGP Sbjct: 763 MPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRG 822 Query: 872 IPGPPGPRGPPG-------------------EGLPGPPGPPGSFLSNSETFLSGPPGPPG 912 + GPPG RG PG +G PG G PG + GP G G Sbjct: 823 LVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAG 882 Query: 913 PPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGD-------- 964 PGP G G PG +G +G QG PG + S+ + GP G PGP GP G+ Sbjct: 883 SPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPG 942 Query: 965 -KGDPGVPGALGI--PSGPSEG-GSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISE 1020 +GDPG G +G P+GP G G G PGP GPPGP G+ G Sbjct: 943 LRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRG-------IV 995 Query: 1021 YMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSS 1080 M + G+ GP G PG GP TG T D V ++G Sbjct: 996 GMPGQRGERGMPGLPGPAGTPGKVGP----TGATGDKGPPGP--VGPPGSNG-------- 1041 Query: 1081 SISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSS 1140 P G PGP G +G+ D A Sbjct: 1042 --------------------------PVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGP 1075 Query: 1141 SGI--SIGLPGPPGPPGLPGTSYEELLSLLRGSE-FRGIVGPPGPPGPPGIPGNVWSSIS 1197 +G+ S G PG PGP G PG + + RG RG +GPPG G G+PG Sbjct: 1076 AGLPGSQGAPGTPGPVGAPGDAGQ------RGDPGSRGPIGPPGRAGKRGLPGPQGPRGD 1129 Query: 1198 VED--------LSSYLHTAGLSFIPGPPGP---------PGPPGPRGPPGVSGALATYAA 1240 D + GL +PGPPGP PGP GPRGPPG G Sbjct: 1130 KGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVG------- 1182 Query: 1241 ENSDSFRSELISYLTSPDVRSFI-----VGPPGPPGPQGPPG 1277 + + + P VR + GPPG PGP GPPG Sbjct: 1183 PSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPG 1224 Score = 397 bits (1019), Expect = e-110 Identities = 229/518 (44%), Positives = 268/518 (51%), Gaps = 71/518 (13%) Query: 565 LRGSPGPKGDMGSPGPKGDRGF------------PGTPGIPGPLGHPGPQGPKGQKGS-- 610 L+G PG +G G+PGPKGDRG G G+PGPLG PGP GP G+KG Sbjct: 760 LQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPG 819 Query: 611 ----VGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGP 666 VG PG G G RG GP G G AGP G G+ G GEPG G G GS GP Sbjct: 820 PRGLVGPPGSRGNPGSRGENGPTGAVGFAGP--QGPDGQPGVKGEPGEPGQKGDAGSPGP 877 Query: 667 KGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGM 726 +G +GSPGP GP G GL+G RG G PG G G G GP G G GP G GEPG Sbjct: 878 QGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGK 937 Query: 727 RGLPGAVGEPGAKGAMG---PAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGP 783 G PG G+PG+ G +G PAGP G G +G+ G G PG GPPGP+G G+ G+ G Sbjct: 938 EGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGM 997 Query: 784 QGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGP 843 G +G G PG PG G PGK+ + + PGP GPPG+ GP G PG GPAG Sbjct: 998 PGQRGERGMPGLPG---PAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGN 1054 Query: 844 AGLPGHQEVLNLQGPPGPPGPRGPPGPS-IPGPPGPRGPPGE-------GLPGPPGPPGS 895 G PG + +G G PGP G PG PG PGP G PG+ G GP GPPG Sbjct: 1055 DGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGR 1114 Query: 896 FLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGP 955 +G G PGP GP+GD+G G RG +G++G GF+ LQG PGP Sbjct: 1115 ---------AGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFT---------GLQGLPGP 1156 Query: 956 PGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQ 1015 PGP G ++G G+PG G P G S GP GP GPPG GS+ +G E Sbjct: 1157 PGPNG---EQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGP 1213 Query: 1016 QYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGE 1053 G GPPGPPGPPG +T G+ Sbjct: 1214 P----------------GEPGPPGPPGPPGHLTAALGD 1235 Score = 381 bits (979), Expect = e-105 Identities = 326/968 (33%), Positives = 380/968 (39%), Gaps = 216/968 (22%) Query: 628 PMGPRGEAGPPGSGEKGERGAA-------GEPGPHGPPGVPGSVGPKGSSGSPGPQGPPG 680 P G G G+KGE G G PGP GPPG G G +G G PGP+GP G Sbjct: 100 PGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQG 159 Query: 681 PVGLQGLRGEVGLPGVKGDKGPMGP---------------------------PGPKGDQG 713 G G+ G+ G PG G GP PG G G Sbjct: 160 IDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVG 219 Query: 714 EKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSG 773 +GP+GL G+ G G G GEPG G MGP G G +GP G+ G G PG G PG G Sbjct: 220 PRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVG 279 Query: 774 DPGKPGLTGPQGPQGLPGTPGR------PGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPG 827 G PG G G GLPG G G KGE GAPG S+G + GP GP G Sbjct: 280 FAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPG----SKGEA-----GPTGPMG 330 Query: 828 AMGPPGPPGAPGP---AGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS-IPGPP------- 876 AMGP GP G PG GP G PG + + G PGP GP G PG S PG P Sbjct: 331 AMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAG 390 Query: 877 -----GPRGPPGE-GLPGPPGP---------------PGSFLSNSETFLSGPP---GPPG 912 GP GP G+ G GPPGP PG+ SGPP GPPG Sbjct: 391 PTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPG 450 Query: 913 PPGPKGDQGPPGPRGHQGEQGLPGFSTSG---SSSFGLNLQGPPGPPGPQGPKGDKGDPG 969 PGP+G GP G RG G+ G+PGF +QGP GPPG +G +G +GDPG Sbjct: 451 SPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPG 510 Query: 970 V---PGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDS 1026 PG +G P G + G PGP G G G + SSG + Sbjct: 511 TVGPPGPVGERGAPGNRGFPGS---DGLPGPKGAQGERGPVGSSGPK------------- 554 Query: 1027 IRSYLSGVQGPPGPPGPPG--PVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISS 1084 G QG PG PG PG +TG GV Sbjct: 555 ------GSQGDPGRPGEPGLPGARGLTGNP-------------------GVQ------GP 583 Query: 1085 EDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGIS 1144 E L L G G PGPPG+ G + S Sbjct: 584 EGKLGPLGAP-----------GEDGRPGPPGSIG-------------------IRGQPGS 613 Query: 1145 IGLPGP---PGPPGLPGTSYEELLSLLRGSEFR-GIVGPPGPPGPPGIPGNVWSSISVED 1200 +GLPGP G PG PG + + RG+ + G VGP GP GPPG+ G Sbjct: 614 MGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGE-------RG 666 Query: 1201 LSSYLHTAGLSFIPGPPGPP---GPPGPRGPPGVSGALATYAAENSDSFRSEL----ISY 1253 G +PGPPGPP G PG +G PG GA+ E I+ Sbjct: 667 EQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITG 726 Query: 1254 LTSPDVRSFIVGPPGP---PGPQGPPGDSRLLSTDA-SHSRGSSSSSHSSSVRRGSSYSS 1309 L + GP GP PGP G PGD+ RG + + R G Sbjct: 727 LPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKG 786 Query: 1310 SMSTGG--------GGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGG 1361 + T G G G G G GE G+ GP G +GP G G G NG Sbjct: 787 AEGTAGNDGARGLPGPLGPPGPAGPTGE-KGEPGPRGL-VGPPGSRG---NPGSRGENGP 841 Query: 1362 LLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSN 1421 FAG + E + + QG G PGP GP G+ + Sbjct: 842 TGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGT 901 Query: 1422 VTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGP---PGHPGPPGPRGHKGEKGD 1478 Q G PG G +G PGP G GPAGP PG GPPG RG G G Sbjct: 902 ---------QGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGR 952 Query: 1479 KGDQVYAG 1486 GD+ AG Sbjct: 953 VGDRGPAG 960 Score = 348 bits (892), Expect = 3e-95 Identities = 217/501 (43%), Positives = 247/501 (49%), Gaps = 89/501 (17%) Query: 562 NGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGP------------------LGHPGPQG 603 N RG PGP G G GP G++G PG G+ GP +G GPQG Sbjct: 793 NDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQG 852 Query: 604 PKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPG----SGEKGERGAAGEPGPHGPPG 659 P GQ G G+PG G G G GP G G GP G G KG RG G PG G PG Sbjct: 853 PDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPG 912 Query: 660 VPGSVGPKGSSGSPGPQGP---PGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGE-- 714 G VGP G +G+PGP GP PG G GLRG+ G G GD+GP GPPG GD+G+ Sbjct: 913 SAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPG 972 Query: 715 ----------KGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPG 764 GP G TG+ G+ G+PG GE G G GPAG G GP G G G PG Sbjct: 973 EDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPG 1032 Query: 765 IRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGP-- 822 GPPG +G G+P GP+GP G GTPGR G GE G G PGP Sbjct: 1033 PVGPPGSNGPVGEP---GPEGPAGNDGTPGRDGAVGERGDRGD------------PGPAG 1077 Query: 823 -PGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGP 881 PG GA G PGP GAPG AG G PG +GP GPPG G G +PGP GPRG Sbjct: 1078 LPGSQGAPGTPGPVGAPGDAGQRGDPGS------RGPIGPPGRAGKRG--LPGPQGPRGD 1129 Query: 882 PGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSG 941 G+ G G G T L G PGPPGP G +G G PGP G +G G G S Sbjct: 1130 KGD--HGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPS--- 1184 Query: 942 SSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPP 1001 +G PGP GP GP G +G G G P GP G PGPPGPP Sbjct: 1185 ------GKEGNPGPLGPIGPPGVRGSVGEAG----PEGP-----------PGEPGPPGPP 1223 Query: 1002 GPPGSISSSGQEIQQYISEYM 1022 GPPG ++++ +I + E M Sbjct: 1224 GPPGHLTAALGDIMGHYDESM 1244 Score = 187 bits (475), Expect = 7e-47 Identities = 203/687 (29%), Positives = 251/687 (36%), Gaps = 118/687 (17%) Query: 850 QEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPG 909 Q+VL+ P PPG P PG G G G G G PG L T + G PG Sbjct: 77 QDVLDCADPVTPPGECCPVCSQTPG--GGNTNFGRGRKGQKGEPG--LVPVVTGIRGRPG 132 Query: 910 PPGPPG---PKGDQGP---PGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKG 963 P GPPG P+G++GP PGPRG QG G P G PG PG GP G Sbjct: 133 PAGPPGSQGPRGERGPKGRPGPRGPQGIDGEP---------------GVPGQPGAPGPPG 177 Query: 964 DKGDPGVPGALGIPSGPSEGG-------SSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQ 1016 PG P L P G S + G GP GP GP G G Sbjct: 178 HPSHPG-PDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGG---- 232 Query: 1017 YISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTI--------TGETFDYSELASHVVSYL 1068 +G GPPG PG PGP+ I G+ + E Sbjct: 233 ---------------AGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPG------- 270 Query: 1069 RTSGYGVSLFSSSISSEDILAVLQRDDVRQYL-RQYLMGPRGPPGPPGASGD-------G 1120 R G F+ S + ++ + + L GP+G G PG+ G+ G Sbjct: 271 RNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMG 330 Query: 1121 SLLSLDYAELSSR--ILSYMSSSGI--SIGLPGPPGP------------PGLPGTSYEEL 1164 ++ L + L + G + G+PG PGP PG PG E Sbjct: 331 AMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAG 390 Query: 1165 LSLLRGSE----FRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPP 1220 + RG E RG GPPGP G PG+PG + + + G S PG GPP Sbjct: 391 PTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTD-GTPGAKGPTGSPGTSGPPGSAGPP 449 Query: 1221 GPPGPRGPPGVSGALATYAAENSDSFRSEL-ISYLTSPDVRSFIVGPPGPPGPQGPPGDS 1279 G PGP+G G G F+ E P +GPPG G +GP GD Sbjct: 450 GSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDP 509 Query: 1280 RLLSTDAS-HSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYG 1338 + RG+ + RG S + G G G G+ G G +G G Sbjct: 510 GTVGPPGPVGERGAPGN-------RGFPGSDGLPGPKGAQGERGPVGSSG-PKGSQGDPG 561 Query: 1339 TDIGPG--GGYGAAAEGGMYAGNG--GLLGADFAGDLDYNELAVRVSESMQRQGLLQGMA 1394 PG G G G+ G G LGA ++ + GL Sbjct: 562 RPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGL----- 616 Query: 1395 YTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGD 1454 GP G G G PG + A D GPPG GE G GP G Sbjct: 617 ---PGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGP 673 Query: 1455 RGPAGPPGHPGPPGPRGHKGEKGDKGD 1481 G G PG PGPPG G G++G GD Sbjct: 674 TGFQGLPGPPGPPGEGGKPGDQGVPGD 700 Score = 92.4 bits (228), Expect = 3e-18 Identities = 89/292 (30%), Positives = 105/292 (35%), Gaps = 54/292 (18%) Query: 1213 IPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRS-ELISYLTSPDVRSFIVGPPGPPG 1271 +P G G PGP GPPG G + R + I + GPPG P Sbjct: 121 VPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPS 180 Query: 1272 PQGPPGDSRLLST-----DASHSRGSSSSSHSSSVRR-GSSYSSSMSTGGGGAGSLGAGG 1325 GP G SR S D GS SV G + GGAG G G Sbjct: 181 HPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPG 240 Query: 1326 AFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQ 1385 G+ G GP G+ GP G G E G NG FAG Sbjct: 241 EPGD-PGPMGPIGSR-GPEGPPGKPGEDGEPGRNGNPGEVGFAGS--------------- 283 Query: 1386 RQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGE 1445 G G PG G PG+ + + +G G KGE Sbjct: 284 ------------PGARGFPGAPGLPGL------------------KGHRGHKGLEGPKGE 313 Query: 1446 MGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 +G PG KG+ GP GP G GP GPRG GE+G G Q G+R + KP Sbjct: 314 VGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKP 365 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 499 bits (1284), Expect = e-140 Identities = 355/977 (36%), Positives = 421/977 (43%), Gaps = 191/977 (19%) Query: 559 EQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPG---PLGHPGPQGPKGQKGSVGDPG 615 +Q N +G PGP+G +G+PG KG G PG PG+PG PLGHPG +GP G+KG+ G PG Sbjct: 642 QQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPG 701 Query: 616 MEGP------------MGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPG 662 GP G RG +G G +GE G PG G+ G +G G+PG GP G G Sbjct: 702 SAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDG 761 Query: 663 SVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGP---PGPKGDQGEKGPRG 719 GPKG +G G +GPPG G +G G GLPG G GP G PGP G GEKG G Sbjct: 762 PEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSG 821 Query: 720 LTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPG 779 TG+PG+ G G G G +G G G G +G G+ G G+PG +G PG G PG PG Sbjct: 822 KTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPG 881 Query: 780 LTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPG 839 GP G QG G PG PG +GE G G+ + +L G G G +G GPPG PG Sbjct: 882 PKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPG 941 Query: 840 PAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS-IPGPPGPRGPPGE----GLPGPPGPPG 894 P G GLPG + +G GPPGP G GP+ + G PGP+G PG+ GL G GPPG Sbjct: 942 PPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPG 1001 Query: 895 SFLSNSETFLSGPPGP------PGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLN 948 +N GP GP PG G +G GP G +G +GE+G PG + L Sbjct: 1002 PVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLG 1061 Query: 949 LQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSIS 1008 GPPG GP G +GDKGD G PG G + G + GP G PGPPG G Sbjct: 1062 PLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADG--- 1118 Query: 1009 SSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYL 1068 + G+ + D +R ++ GV GPPG G PGP GE D + H Sbjct: 1119 AQGRRGPPGLFGQKGDDGVRGFV-GVIGPPGLQGLPGPPGE-KGEVGDVGSMGPHGAP-- 1174 Query: 1069 RTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYA 1128 GPRGP GP G+ G Sbjct: 1175 -------------------------------------GPRGPQGPTGSEG---------- 1187 Query: 1129 ELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGI 1188 + GLPG G PG G E RG G PGPPG PGI Sbjct: 1188 ---------------TPGLPGGVGQPGAVGEKGE-----------RGDAGDPGPPGAPGI 1221 Query: 1189 PGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRS 1248 PG G GP G GPPG +GPPG GA + Sbjct: 1222 PGPKGD-------------IGEKGDSGPSGAAGPPGKKGPPGEDGAKGS----------- 1257 Query: 1249 ELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDAS-HSRGSSSSSHSSSVRRGSSY 1307 VGP G PG GPPGD + D S +G S Sbjct: 1258 ---------------VGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGE 1302 Query: 1308 SSSMSTGG--GGAGSLGAGGAFGE--AAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLL 1363 + G G +G +G G GE A G+ GP G G G GA G G GL Sbjct: 1303 PGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPP-GRTGPMGARGPPGR-VGPEGLR 1360 Query: 1364 GADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVT 1423 G + + GLL A GPPG GP G PG+ Sbjct: 1361 G---------------IPGPVGEPGLLG--APGQMGPPGPLGPSGLPGLKGDTGPKGE-- 1401 Query: 1424 ADLMDFFQTYGAIQGPPGQKGE---------MGTPGPKGDRGPAGP---PGHPGPPGPRG 1471 G I GPPG+ GE G PGPKGD GP GP GHPGPPG G Sbjct: 1402 ---KGHIGLIGLI-GPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAG 1457 Query: 1472 HKGEKGDKGDQVYAGRR 1488 G+KG KG G R Sbjct: 1458 PLGQKGSKGSPGSMGPR 1474 Score = 479 bits (1232), Expect = e-134 Identities = 369/1047 (35%), Positives = 447/1047 (42%), Gaps = 193/1047 (18%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGP---------LGHPGPQGPKGQKGSVGDPGME 617 G+ G +G G GPKGDRGF G PG+PG +G PGP G G++G+ G PG Sbjct: 533 GADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPT 592 Query: 618 GPMGQRGREGPMGPRGEAGPPG----SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSP 673 G G+ G G +GPRG GP G +G G GA G GP G PG PG G GS G P Sbjct: 593 GQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLP 652 Query: 674 GPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGE------PGMR 727 GPQG G G +G G G+PG+ G GP+G PG +G GEKG +G G PG R Sbjct: 653 GPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPR 712 Query: 728 GLPGAVGEPGAKGAMGPAGPDGHQG------PRGEQGLTGMPGIRGPPGPSGDPGKPGLT 781 G+ G G G +G G G DG G +G+QG G PG RG GP G G+ G Sbjct: 713 GVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQA 772 Query: 782 GPQGPQG------------LPGTPGRPGIKGEPGAPGKI--VTSEGSSMLTVP------- 820 G +GP G LPG PGRPG KG G PG + + +G S T Sbjct: 773 GEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGER 832 Query: 821 GPPGP------PGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG----P 870 GPPG PGA G PGP G G G G+PG + + LQGPPG PGP+GPPG Sbjct: 833 GPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKD 892 Query: 871 SIPGPPGPRGPPG-EGLPGPPGPPGSFLSNSETFL------SGPPGPPGPPGP------- 916 PG PG RG G +G GPPGP G +T GPPGPPGPPG Sbjct: 893 GRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLE 952 Query: 917 -----KGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVP 971 KG+ GPPGP G +G GL GF +G PG PGP G KGDKG PG Sbjct: 953 GREGAKGELGPPGPLGKEGPAGLRGFPGP---------KGGPGDPGPTGLKGDKGPPGPV 1003 Query: 972 GALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYL 1031 GA G P G + + + G G GP GP G S G+ + + + Sbjct: 1004 GANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPP-------GPTGKDGI 1056 Query: 1032 SGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVL 1091 G GP GPPG GP +GE D ++ + + + G Sbjct: 1057 PGPLGPLGPPGAAGP----SGEEGDKGDVGAP--GHKGSKG------------------- 1091 Query: 1092 QRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGIS--IGLPG 1149 + D + + GP G PGPPGA G + G+ +G+ G Sbjct: 1092 DKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRG------PPGLFGQKGDDGVRGFVGVIG 1145 Query: 1150 PPGPPGLPGTSYEE-LLSLLRGSEFRGIVGPPGPPGP------PGIPGNVWSSISVEDLS 1202 PPG GLPG E+ + + G GP GP GP PG+PG V +V + Sbjct: 1146 PPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKG 1205 Query: 1203 SYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSF 1262 G + PGPPG PG PGP+G G G A + D Sbjct: 1206 E----RGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGP-----PGEDGAKG 1256 Query: 1263 IVGPPGPPGPQGPPGDSRLLSTDASHS-RGSSSSSHSSSVRRGSSYSSSMSTGG--GGAG 1319 VGP G PG GPPGD + D S +G S + G G +G Sbjct: 1257 SVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSG 1316 Query: 1320 SLGAGGAFGEAAGDRGPYGTDIGPG--GGYGAAAEGGMYAGNGGLLGADFAGDLDYNELA 1377 +G G GE G +G G D PG G GA G G GL G Sbjct: 1317 HMGREGREGEK-GAKGEPGPDGPPGRTGPMGARGPPGR-VGPEGLRG------------- 1361 Query: 1378 VRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVT-ADLMDFFQTYG-- 1434 + + GLL GPPG GP G PG+ L+ G Sbjct: 1362 --IPGPVGEPGLLGAPGQ--MGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEA 1417 Query: 1435 ---------AIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGD---KGDQ 1482 +QGPPG KG+ G PGP G G GPPG GP G +G KG G +GD Sbjct: 1418 GEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDT 1477 Query: 1483 VYAG--------------RRRRRSIAV 1495 AG RRRRR + V Sbjct: 1478 GPAGPPGPPGAPAELHGLRRRRRFVPV 1504 Score = 449 bits (1154), Expect = e-125 Identities = 352/996 (35%), Positives = 417/996 (41%), Gaps = 186/996 (18%) Query: 557 MMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGM 616 +++Q +++G PGP G G PGP G PG PG+ G G GPQGP+G +G G PG Sbjct: 469 VLQQTQLSMKGPPGPVGLTGRPGPVG---LPGHPGLKGEEGAEGPQGPRGLQGPHGPPGR 525 Query: 617 EGPMGQRGREGPMGPRGEAGPPGS----------GEKGERGA---AGEPGP--------- 654 G MG+ G +G G G+ GP G GEKG+RG G+PGP Sbjct: 526 VGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGA 585 Query: 655 HGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGE 714 GPPG G G G G GP+G PGP G G+ G G PG KG+ GP G PGP G QG Sbjct: 586 EGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGN 645 Query: 715 KG------PRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGP 768 G P+GL G PG +G PG G PG G+ GP G GH+GP GE+G G PG GP Sbjct: 646 HGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGP 705 Query: 769 PG---PSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGP 825 PG P G G G G QG +G G G PG KG+ G G +G PG PGP Sbjct: 706 PGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKG----DQGK-----PGAPGP 756 Query: 826 PGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS----IPGPPGPRGP 881 G GP GP G G AG G PG G PG PG G PGP PGP GP G Sbjct: 757 RGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGE 816 Query: 882 PGE-------GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGL 934 G+ GL G GPPGS G PG G PGPKGD G G G GE+GL Sbjct: 817 KGKSGKTGQPGLEGERGPPGSRGER------GQPGATGQPGPKGDVGQDGAPGIPGEKGL 870 Query: 935 PGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGP 994 PG LQGPPG PGP+GP G +G G PG P + G +GP Sbjct: 871 PG------------LQGPPGFPGPKGPPGHQGKDGRPGH------PGQRGELGFQGQTGP 912 Query: 995 PGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGET 1054 PGP G GP G G ++ G GPPGPPG G + + G Sbjct: 913 PGPAGVLGPQGKTGEVGPLGER----------------GPPGPPGPPGEQG-LPGLEGRE 955 Query: 1055 FDYSELASHVVSYLRTSG-YGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGP 1113 EL L G G+ F L G +GPPGP Sbjct: 956 GAKGELGPP--GPLGKEGPAGLRGFPGPKGGPGDPGPTG-----------LKGDKGPPGP 1002 Query: 1114 PGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPG------PPGPPGLPGTSYEELLSL 1167 GA+G S + +G IGLPG P GP G G+ E Sbjct: 1003 VGANG------------SPGERGPLGPAG-GIGLPGQSGSEGPVGPAGKKGSRGERGPPG 1049 Query: 1168 LRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLH--TAGLSFIPGPPGPPGPPGP 1225 G + GI GP GP GPPG G D+ + H + G GPPG PG GP Sbjct: 1050 PTGKD--GIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGP 1107 Query: 1226 RGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFI--VGPPGPPGPQGPPGDSRLLS 1283 G PG GA L VR F+ +GPPG G GPPG+ + Sbjct: 1108 AGHPGPPGADGAQGRRGPPG----LFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVG 1163 Query: 1284 TDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTD--I 1341 S + GS + + G G G++G G G+A GD GP G Sbjct: 1164 DVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDA-GDPGPPGAPGIP 1222 Query: 1342 GPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPP 1401 GP G G + G +G G G D + +V GP Sbjct: 1223 GPKGDIGEKGDSGP-SGAAGPPGKKGPPGEDGAKGSV--------------------GPT 1261 Query: 1402 GQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPP 1461 G PG GPPG V I G PG+KG+ GD G GPP Sbjct: 1262 GLPGDLGPPGDPGV------------------SGIDGSPGEKGD------PGDVGGPGPP 1297 Query: 1462 GHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 G G PG G G++G G GR + +P Sbjct: 1298 GASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEP 1333 Score = 428 bits (1101), Expect = e-119 Identities = 337/972 (34%), Positives = 396/972 (40%), Gaps = 158/972 (16%) Query: 570 GPKGDMGSPG--PKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREG 627 G KG G P KG + F G PG PGP G GP GP G G GDPG GP G G G Sbjct: 373 GEKGAKGEPAVIEKGQQ-FEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPG 431 Query: 628 PMGPRGEAG----------------PPGS------------------GEKGERGAAGEPG 653 G RG G PP S G G G G PG Sbjct: 432 IDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPG 491 Query: 654 PHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQG 713 P G PG PG G +G+ G GP+G GP G G G++G PG G +G G GPKGD+G Sbjct: 492 PVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRG 551 Query: 714 EKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGP---PG 770 G GL GE G RG G VG+PG G G G +G GP G+ G G G+ GP PG Sbjct: 552 FDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPG 611 Query: 771 PSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMG 830 P+G PG G+ G G +G G PG PG G+ G G ++ PG GPP G Sbjct: 612 PTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPP---G 668 Query: 831 PPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPG----EGL 886 PG PG PG GP G PGH+ +G GPPG GPPG PGP G +G G +G Sbjct: 669 NPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPG--YPGPRGVKGTSGNRGLQGE 726 Query: 887 PGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFG 946 G G G + L G G PG PGP+G+ GP GP+G G+ G G S Sbjct: 727 KGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGK 786 Query: 947 LNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGS 1006 L + G PG PG GPKG G PG G +G + G GPPG G G PG+ Sbjct: 787 LGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGA 846 Query: 1007 ISSSGQ--EIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGP-----VTTITGETFDYSE 1059 G ++ Q + + + L G+QGPPG PGP GP G E Sbjct: 847 TGQPGPKGDVGQDGAPGIPGE---KGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGE 903 Query: 1060 LASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGD 1119 L F VL + +G RGPPGPPG G+ Sbjct: 904 LG----------------FQGQTGPPGPAGVLGPQGKTGEVGP--LGERGPPGPPGPPGE 945 Query: 1120 GSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGP 1179 L L+ E + G GPPGP G G + LRG F G G Sbjct: 946 QGLPGLEGREGAK-------------GELGPPGPLGKEGPAG------LRG--FPGPKGG 984 Query: 1180 PGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYA 1239 PG PGP G+ G+ V G + PG GP GP G G PG SG+ Sbjct: 985 PGDPGPTGLKGDKGPPGPV----------GANGSPGERGPLGPAGGIGLPGQSGSEGPVG 1034 Query: 1240 AENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSS 1299 R E P + G PGP GP GPPG + + + S Sbjct: 1035 PAGKKGSRGE-----RGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGS 1089 Query: 1300 SVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGT-----DIGPGGGYGAAAEGG 1354 +G + G AG G GA G A G RGP G D G G G G Sbjct: 1090 KGDKGDAGPPGQPGIRGPAGHPGPPGADG-AQGRRGPPGLFGQKGDDGVRGFVGVIGPPG 1148 Query: 1355 MYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISK 1414 + G GD+ GP G PGP+GP G Sbjct: 1149 LQGLPGPPGEKGEVGDVG------------------------SMGPHGAPGPRGPQG--- 1181 Query: 1415 VFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKG 1474 S T L G GQ G +G G +GD G GPPG PG PGP+G G Sbjct: 1182 --PTGSEGTPGL----------PGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIG 1229 Query: 1475 EKGDKGDQVYAG 1486 EKGD G AG Sbjct: 1230 EKGDSGPSGAAG 1241 Score = 380 bits (977), Expect = e-105 Identities = 235/559 (42%), Positives = 264/559 (47%), Gaps = 74/559 (13%) Query: 559 EQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEG 618 EQ L G G KG++G PGP G G G G PGP G PG GP G KG G PG G Sbjct: 945 EQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVG 1004 Query: 619 PMGQRGREGPMGPRGEAGPPG----------SGEKGERGAAGEPGPHGPPGVPGSVGP-- 666 G G GP+GP G G PG +G+KG RG G PGP G G+PG +GP Sbjct: 1005 ANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLG 1064 Query: 667 ----------------------KGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMG 704 KGS G G GPPG G++G G G PG G +G G Sbjct: 1065 PPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRG 1124 Query: 705 PPG---PKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTG 761 PPG KGD G +G G+ G PG++GLPG GE G G +G GP G GPRG QG TG Sbjct: 1125 PPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTG 1184 Query: 762 MPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVP- 820 G G PG G PG G G +G G PG PG PGI G G G+ S S P Sbjct: 1185 SEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPG 1244 Query: 821 --GPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG-------PS 871 GPPG GA G GP G PG GP G PG + G G PG G PG P Sbjct: 1245 KKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPG 1304 Query: 872 IPGPPGPRGPPG----EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRG 927 PGPPG RGP G EG G G G GP GPPG GP G +GPPG G Sbjct: 1305 APGPPGKRGPSGHMGREGREGEKGAKGE---------PGPDGPPGRTGPMGARGPPGRVG 1355 Query: 928 HQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQ---------GPKGDKGDPGVPGALGIPS 978 +G +G+PG GPPGP GP GPKG+KG G+ G +G P Sbjct: 1356 PEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPG 1415 Query: 979 GPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYM-QSDSIRSYLS----G 1033 E G V GPPGP G PGPPG I S G ++ + Q S S S G Sbjct: 1416 EAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRG 1475 Query: 1034 VQGPPGPPGPPGPVTTITG 1052 GP GPPGPPG + G Sbjct: 1476 DTGPAGPPGPPGAPAELHG 1494 Score = 213 bits (543), Expect = 9e-55 Identities = 224/733 (30%), Positives = 269/733 (36%), Gaps = 179/733 (24%) Query: 826 PGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPP---GPRGPPG----PSIPGPPGP 878 PGA G GA G PA + Q+ G PGP GP GPPG P PGPPGP Sbjct: 370 PGA----GEKGAKGE--PAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGP 423 Query: 879 RGPPG----EGLPGPP----------------GPPGSF--------LSNSETFLSGPPGP 910 G PG +G+ GPP GPP SF L ++ + GPPGP Sbjct: 424 AGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGP 483 Query: 911 ------------PGPPGPKGD---QGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGP 955 PG PG KG+ +GP GPRG QG G PG +G PG Sbjct: 484 VGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGD 543 Query: 956 PGPQGPKGDKGDPGVPGA---------LGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGS 1006 GP+G +G G PG+PG +G P P E G GP G G PGP G Sbjct: 544 TGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGL 603 Query: 1007 ISSSGQEIQQYISEYMQSDSIRSYLSGVQGPP------GPPGPPGPVTTITGETFDY-SE 1059 + G + R ++G+ G P GPPG PGP G+ ++ S+ Sbjct: 604 LGPRGS----------PGPTGRPGVTGIDGAPGAKGNVGPPGEPGP----PGQQGNHGSQ 649 Query: 1060 LASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGD 1119 + T G GP G PG PG G Sbjct: 650 GLPGPQGLIGTPGE-------------------------------KGPPGNPGIPGLPGS 678 Query: 1120 GSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGP 1179 L E + G S G PG PGP G+ GTS RG+ G Sbjct: 679 DGPLGHPGHEGPTGEKGAQGPPG-SAGPPGYPGPRGVKGTSGN-----------RGLQGE 726 Query: 1180 PGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYA 1239 G G G PG + G PG PGP G GP GP G +G Sbjct: 727 KGEKGEDGFPG----------FKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEG 776 Query: 1240 AENSDSFRSEL-ISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHS 1298 S + +L + L R G G PGP GP G+ Sbjct: 777 PPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPG 836 Query: 1299 SSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAA--GDRGPYGTDIGPGGGYGAAAEGGM- 1355 S RG ++ G G GA G GE G +GP G GP G G + G Sbjct: 837 SRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFP-GPKGPPGHQGKDGRP 895 Query: 1356 -YAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQ-GPPGQPGPQGPPGIS 1413 + G G LG F G A G+L T + GP G+ GP GPPG Sbjct: 896 GHPGQRGELG--FQGQTGPPGPA----------GVLGPQGKTGEVGPLGERGPPGPPGPP 943 Query: 1414 KVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPA------GPPGHPGPP 1467 Q ++G G KGE+G PGP G GPA GP G PG P Sbjct: 944 GE---------------QGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDP 988 Query: 1468 GPRGHKGEKGDKG 1480 GP G KG+KG G Sbjct: 989 GPTGLKGDKGPPG 1001 Score = 115 bits (288), Expect = 3e-25 Identities = 124/406 (30%), Positives = 151/406 (37%), Gaps = 98/406 (24%) Query: 1118 GDGSLLSLDY--AELSSRILSYMSSSGISIGLPGPP----------GPPGLPGTSYEELL 1165 GD S + D+ AE SR + G G P GPPG PG Sbjct: 346 GDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGP------ 399 Query: 1166 SLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGP------ 1219 +G+VGP GPPGPPG PG+ PGPPGP Sbjct: 400 --------QGVVGPSGPPGPPGFPGD----------------------PGPPGPAGLPGI 429 Query: 1220 PGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTS------PDVRSFIVGPPGP---- 1269 PG G RGPPG + A SF+ +S+ + + + GPPGP Sbjct: 430 PGIDGIRGPPGTVIMMPFQFA--GGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLT 487 Query: 1270 --PGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAF 1327 PGP G PG L + + RG G G GA GA Sbjct: 488 GRPGPVGLPGHPGLKGEEGAEGPQGP---------RGLQGPHGPPGRVGKMGRPGADGAR 538 Query: 1328 GEAAGDRGPYGTDIGPGGGYGAAAEGGM-----YAGNGGLLGADFAGDLDYNELAVRVSE 1382 G GD GP G D G G G E G + G G G D + + Sbjct: 539 G-LPGDTGPKG-DRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAG 596 Query: 1383 SMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVF---SAYSNV---TADLMDFFQTYGAI 1436 +GLL GP G PGP G PG++ + A NV Q Sbjct: 597 EPGPRGLL--------GPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGS 648 Query: 1437 QGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQ 1482 QG PG +G +GTPG KG G G PG PG GP GH G +G G++ Sbjct: 649 QGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEK 694 Score = 112 bits (280), Expect = 3e-24 Identities = 114/416 (27%), Positives = 143/416 (34%), Gaps = 114/416 (27%) Query: 1102 QYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGT-- 1159 Q ++GP GPPGPPG GD G PGP G PG+PG Sbjct: 400 QGVVGPSGPPGPPGFPGDP-------------------------GPPGPAGLPGIPGIDG 434 Query: 1160 ------SYEELLSLLRGSEFRG--------------------IVGPPGPPGPPGIPGNVW 1193 + + G F+G + GPPGP G G PG V Sbjct: 435 IRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPV- 493 Query: 1194 SSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISY 1253 L + G GP GP G GP GPPG G + A+ + + Sbjct: 494 ------GLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGD---- 543 Query: 1254 LTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMST 1313 T P G PG PG +G GD + + G + Sbjct: 544 -TGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRG 602 Query: 1314 GGGGAGSLGAGGAFGEAAGDRGPYGT-DIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLD 1372 G GS G G G D P ++GP G G + G + G+ GL G Sbjct: 603 LLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNH-GSQGLPGP------- 654 Query: 1373 YNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQT 1432 QGL+ G PG+ GP G PGI + + Sbjct: 655 --------------QGLI--------GTPGEKGPPGNPGIPGLPGS-------------- 678 Query: 1433 YGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRR 1488 GP G G G G KG +GP G G PG PGPRG KG G++G Q G + Sbjct: 679 ----DGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEK 730 Score = 54.7 bits (130), Expect = 7e-07 Identities = 30/77 (38%), Positives = 37/77 (48%), Gaps = 12/77 (15%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGI------------PGPLGHPGPQGPKGQKGSVG 612 ++G PGPKGD G PGP G G PG PG+ PG +G G GP G G G Sbjct: 1428 VQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPG 1487 Query: 613 DPGMEGPMGQRGREGPM 629 P + +R R P+ Sbjct: 1488 APAELHGLRRRRRFVPV 1504 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 498 bits (1282), Expect = e-140 Identities = 374/1012 (36%), Positives = 429/1012 (42%), Gaps = 189/1012 (18%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGH---PGPQGP---------KGQKGSVGDP 614 GS G +G G GPKGDRGF G G+PG GH PGP GP +G G VG Sbjct: 613 GSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPR 672 Query: 615 GMEGPMGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSP 673 G+ G G RG GP GP G GPPG +G G+ G G GP G PG PG G G+ G P Sbjct: 673 GLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLP 732 Query: 674 GPQGPPGPVGLQGLRGEVGLPGVKG---------------DKGPMGPPGPKGDQGEKGPR 718 GPQG GP G +G G+ GLPG+ G +KG GPPGP+G G GPR Sbjct: 733 GPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPR 792 Query: 719 GLTGEPGMRGLPGAVGE------PGAKGAMG------------PAGPDGHQGPRGEQGLT 760 G+ G G+RGL G GE PG KG MG P G DG +GP+G G Sbjct: 793 GVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPN 852 Query: 761 GMPGIRGPPGPSGD---PGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSML 817 G PG GPPG G PG PG G QGP+G G PG PG GE G G Sbjct: 853 GDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRG----------- 901 Query: 818 TVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS----IP 873 PG PGP G GP GP G GP G G PG + GP GPPG RGP GP P Sbjct: 902 -TPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFP 960 Query: 874 GPPGPRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQG-- 930 GP GP GPPG +GLPG PG G +T GPPG GP GP G+ GP G RGH G Sbjct: 961 GPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPP 1020 Query: 931 ----EQGLPGFS----TSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSE 982 EQGLPG + T G L G GPPG +G GD+G PG GALG+ Sbjct: 1021 GPPGEQGLPGLAGKEGTKGDPG-PAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGN--- 1076 Query: 983 GGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPG 1042 GPPGPPGP G PG +G + G+ G PGP G Sbjct: 1077 ---------EGPPGPPGPAGSPGERGPAGA----------------AGPIGIPGRPGPQG 1111 Query: 1043 PPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQ 1102 PPGP GE E RD ++ + Sbjct: 1112 PPGPA----GEKGAPGEKGPQ-------------------------GPAGRDGLQGPVG- 1141 Query: 1103 YLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGIS-----IGLPGPPGPPGLP 1157 L GP GP GPPG GD + + S G + IG PGP G G P Sbjct: 1142 -LPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEP 1200 Query: 1158 GTSYEELLSLLRGSEF-RGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGP 1216 G ++ L +G E RG GPPGP G G+PG D+ GP Sbjct: 1201 GPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQM----------GP 1250 Query: 1217 PGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPP 1276 PGPPGP GP G PG G + E P G PG PG GPP Sbjct: 1251 PGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEK----GEPGE----AGEPGLPGEGGPP 1302 Query: 1277 GDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAA--GDR 1334 G RG S S G G GS G G G+ G+ Sbjct: 1303 GPKG--------ERGEKGESGPSGAA-GPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEP 1353 Query: 1335 GPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMA 1394 GP G D GP G G E G G+ G G + RQG Sbjct: 1354 GPAGQD-GPPGDKGDDGEPGQ-TGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKG 1411 Query: 1395 YT-VQGPPGQPGPQGP------PGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMG 1447 ++GPPG+ GP GP PG + V + GPPG G G Sbjct: 1412 EAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSP---GPDGPPGPMGPPG 1468 Query: 1448 TPGPKGDRGPAGPPGHPG------PPGPRGHKGEKGDKGDQVYAGRRRRRSI 1493 PG KGD GP G GHPG PPG +G KG++G G Q +G + + I Sbjct: 1469 LPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGI 1520 Score = 497 bits (1279), Expect = e-140 Identities = 362/1017 (35%), Positives = 420/1017 (41%), Gaps = 272/1017 (26%) Query: 559 EQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPG---PLGHPGPQGPKGQKGSVGDPG 615 +Q N +G PGP+G +G PG KG G PG PG+PG P GHPG +GP G+KG G PG Sbjct: 722 QQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPG 781 Query: 616 MEGPMGQ------------RGREGPMGPRGEAGPPG----SGEKGERGAAGEPGPHGPPG 659 +GP+G RG +G G +GE G PG G KG+RG G PGP G G Sbjct: 782 PQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDG 841 Query: 660 VPGSVGPKGSSGSPGPQGPPGP------------VGLQGLRGEV---GLPGVKGDKGPMG 704 G G G +G PGP GPPG G QG +G + G PG G+KG G Sbjct: 842 PEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRG 901 Query: 705 PPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPG 764 PG G +G++GP G GE G RG+ G G G G GPAGP G +GP G QG TG PG Sbjct: 902 TPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPG 961 Query: 765 IRGPPGP---------------------SGDPGKPGLTGPQGP---------QGLPGTPG 794 +GPPGP +G PG PG+ GPQGP +G PG PG Sbjct: 962 PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPG 1021 Query: 795 RPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLN 854 PG +G PG GK T +PG GPPG G PG G PGP G GL G+ Sbjct: 1022 PPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGN----- 1076 Query: 855 LQGPPGPPGPRGPPGP----------SIPGPPGPRGPPG----EGLP---GPPGPPGSFL 897 +GPPGPPGP G PG IPG PGP+GPPG +G P GP GP G Sbjct: 1077 -EGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1135 Query: 898 SNSETFLSGPPGPPGPP------------------GPKGDQGPPGPRGHQGEQGLPGFST 939 L GP GP GPP G KG+QGPPGP G QG G PG S Sbjct: 1136 LQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSG 1195 Query: 940 SGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPG 999 + QG G G +GP+G G PG G G+P P E G + + GPPGPPG Sbjct: 1196 ADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPG 1255 Query: 1000 PPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSE 1059 P GP G+ + G QGPPG G PG V GE + E Sbjct: 1256 PRGPSGAPGADGP----------------------QGPPGGIGNPGAV----GEKGEPGE 1289 Query: 1060 LASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGD 1119 L G GPPGP G G+ Sbjct: 1290 AG---------------------------------------EPGLPGEGGPPGPKGERGE 1310 Query: 1120 GSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGP 1179 SG S G GPPGP G PG +GS G VG Sbjct: 1311 ------------------KGESGPS-GAAGPPGPKGPPGDDGP------KGSP--GPVGF 1343 Query: 1180 PGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGP---PGPPGPPGPRGPPGVSGALA 1236 PG PGPPG PG D G + PGP PGP GPPG RGPPG +G Sbjct: 1344 PGDPGPPGEPGPAGQDGPPGDKGDD-GEPGQTGSPGPTGEPGPSGPPGKRGPPGPAG--- 1399 Query: 1237 TYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSS 1296 P+ R G G G +GPPG + + + + Sbjct: 1400 --------------------PEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGL 1439 Query: 1297 HSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPG--GGYGAAAEGG 1354 G G G +G G G GD GP G PG G G E G Sbjct: 1440 RGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPG-LKGDSGPKGEKGHPGLIGLIGPPGEQG 1498 Query: 1355 MYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISK 1414 G+ GL G + S QG + GP G GP GPPG Sbjct: 1499 -EKGDRGLPGPQGS------------SGPKGEQG--------ITGPSGPIGPPGPPG--- 1534 Query: 1415 VFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRG 1471 + GPPG KG G+ GP G +G AG PG PGPPGP G Sbjct: 1535 ---------------------LPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570 Score = 486 bits (1252), Expect = e-137 Identities = 384/1124 (34%), Positives = 451/1124 (40%), Gaps = 263/1124 (23%) Query: 532 GADLDKIGLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPG 591 G D G +QE + + +++Q LRG GP G G PGP G G G G Sbjct: 529 GGDAGSKGPMVSAQES-----QAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKG 583 Query: 592 IPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQ---RGREGPMGPRGEAGPPG-SGEKGERG 647 PG +G GP+G +G G G PG G G RG G GP+G+ G G +G GE+G Sbjct: 584 EPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKG 643 Query: 648 AAGEPGPHGPPGVPGS---------VGPKGSSGSPGPQG---------PPGPVGLQGLRG 689 G+PGP GPPG PG VGP+G G PGP+G PPGP G+ G+ G Sbjct: 644 HRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDG 703 Query: 690 EVGLPGVKGDKGPMGPPGPKGDQGEKGPRGL---------------TGEPGMRGLPGAVG 734 + PG KG+ GP G PGP G QG G +GL G+PG+ G+PGA G Sbjct: 704 Q---PGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADG 760 Query: 735 EPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIR---------------------------- 766 PG G GP G G QGP G QG G PG R Sbjct: 761 PPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKG 820 Query: 767 -----------GPP---------------GPSGDP---GKPGLTGPQGPQGLPGTPGRPG 797 GPP GP+GDP G PG G G GLPG PGR G Sbjct: 821 DMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQG 880 Query: 798 IKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQG 857 KG G PG + PG PGP G GP GP G GP G G PG + G Sbjct: 881 PKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDG 940 Query: 858 PPGPPGPRGPPGP----SIPGPPGPRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPPG 912 P GPPG RGP GP PGP GP GPPG +GLPG PG G +T GPPG G Sbjct: 941 PAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVG 1000 Query: 913 PPGPKGDQGP------PGPRGHQGEQGLPGFS----TSGSSSFGLNLQGPPGPPGPQGPK 962 P GP G+ GP PGP G GEQGLPG + T G L G GPPG +G Sbjct: 1001 PQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPG-PAGLPGKDGPPGLRGFP 1059 Query: 963 GDKGDPGVPGALGI--------PSGPS-------EGGSSSTMYVSGPPGPPGPPGPPGSI 1007 GD+G PG GALG+ P GP+ G++ + + G PGP GPPGP G Sbjct: 1060 GDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEK 1119 Query: 1008 SSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSY 1067 + G+ + Q + R L G G PGP GP GP GE D E+ Sbjct: 1120 GAPGE-------KGPQGPAGRDGLQGPVGLPGPAGPVGP----PGEDGDKGEIGEP---- 1164 Query: 1068 LRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDY 1127 S D G +GPPGP G G Sbjct: 1165 -----------GQKGSKGD------------------KGEQGPPGPTGPQG--------- 1186 Query: 1128 AELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEF-RGIVGPPGPPGPP 1186 IG PGP G G PG ++ L +G E RG GPPGP G Sbjct: 1187 ----------------PIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQ 1230 Query: 1187 GIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSG-----------AL 1235 G+PG D+ GPPGPPGP GP G PG G Sbjct: 1231 GLPGPPGEKGETGDVGQM----------GPPGPPGPRGPSGAPGADGPQGPPGGIGNPGA 1280 Query: 1236 ATYAAENSDSFRSELISYLTSPDVR--------SFIVGPPGPPGPQGPPGDSRLLSTDAS 1287 E ++ L P + S G GPPGP+GPPGD + Sbjct: 1281 VGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGP 1340 Query: 1288 HSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAA-----GDRGPYGT--D 1340 G G G G+ G GE G RGP G Sbjct: 1341 VGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGP 1400 Query: 1341 IGPGGGYGAAAEGGMYA--GNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQ 1398 G G GA E G+ G G +G A + + + QGL Sbjct: 1401 EGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGS-----P 1455 Query: 1399 GPPGQPGPQGPPGISKVFSAYSNVTAD-----LMDFFQTYG-----------AIQGPPGQ 1442 GP G PGP GPPG+ + S + L+ G QG G Sbjct: 1456 GPDGPPGPMGPPGLPGL-KGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGP 1514 Query: 1443 KGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 KGE G GP G GP GPPG PGPPGP+G KG G G + AG Sbjct: 1515 KGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAG 1558 Score = 483 bits (1242), Expect = e-136 Identities = 365/1071 (34%), Positives = 428/1071 (39%), Gaps = 256/1071 (23%) Query: 565 LRGSPGPKGDMGSPGPKG------------DRGFPGTPGIPGPLGHPGPQGPK------- 605 + G PGP+G G PGP G +RG PG PG+PG G PGP G Sbjct: 467 IEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRF 526 Query: 606 ---GQKGSVGDP--------------------GMEGPMGQRGREGPMGPRGEAGPPGS-- 640 G GS G G GPMG GR GP+GP G G G Sbjct: 527 GGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPG 586 Query: 641 --GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKG 698 G +G RG G PGP G PG G G G+ G PG GP G G GL G G G +G Sbjct: 587 DVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRG 646 Query: 699 DKGPMGPPGPKGDQGEKG------PRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQG 752 D GP GPPGP GD GE+G PRGL GEPG RGL G G PG G G G DG G Sbjct: 647 DPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPG 706 Query: 753 PRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQG---------PQGLPGTPGRPGIKGEPG 803 P+G G G PG PPG G+PG GL GPQG P G PG PG PG G PG Sbjct: 707 PKGNVGPQGEPG---PPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPG 763 Query: 804 APGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPG--- 860 PGK GPPG G GPPGP G G GP G+ G + L+G G Sbjct: 764 HPGK------------EGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKG 811 Query: 861 ---------------------PPGPRGPPGPSIP-------GPPGPRGPPGE----GLPG 888 PPGPRG GP P G PGP GPPGE G+PG Sbjct: 812 EDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPG 871 Query: 889 PPGPPGSFLSNSETFLSGPPGP---------PGPPGPKGDQGPPGPRGHQGEQGLPGFST 939 PG PG G PG PG PGP+G +GP GPRG +G +G+ G Sbjct: 872 LPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPG 931 Query: 940 SGSSSFGLNLQGPPGPPGPQGPKGD------KGDPGVPGALGIPSGPSEGGSSSTMYVSG 993 +S G GPPG GP GP+G KG PG PG G+P P + G + +G Sbjct: 932 PKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 991 Query: 994 PPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGE 1053 PPGPPG GP G +G ++ G GPPGPPG G + + G+ Sbjct: 992 PPGPPGVVGPQGPTGETGPMGER----------------GHPGPPGPPGEQG-LPGLAGK 1034 Query: 1054 TFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGP 1113 + + + G+ F + L L G GPPGP Sbjct: 1035 EGTKGDPGPAGLPG-KDGPPGLRGFPGDRGLPGPVGALG-----------LKGNEGPPGP 1082 Query: 1114 PGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSE- 1172 PG +G + + IG+PG PGP G PG + E+ +G + Sbjct: 1083 PGPAGSPGERG-------------PAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQG 1129 Query: 1173 ------FRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPR 1226 +G VG PGP GP G PG + + + G GPPGP GP GP Sbjct: 1130 PAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGE-PGQKGSKGDKGEQGPPGPTGPQGPI 1188 Query: 1227 GPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQG---PPGDSRLLS 1283 G PG SGA E + L R F GPPGP G QG PPG+ Sbjct: 1189 GQPGPSGA----DGEPGPRGQQGLFGQKGDEGPRGF-PGPPGPVGLQGLPGPPGEKGETG 1243 Query: 1284 TDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAA-----GDRGPYG 1338 S G+ G G G++G G GEA G+ GP G Sbjct: 1244 DVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPG 1303 Query: 1339 T--------DIGPGGGYGAAAEGGMYAGNGGLLGAD----FAGDLDYNELAVRVSESMQR 1386 + GP G G G G+ G G+ F GD Sbjct: 1304 PKGERGEKGESGPSGAAGPPGPKGP-PGDDGPKGSPGPVGFPGD---------------- 1346 Query: 1387 QGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEM 1446 GPPG+PGP G GPPG KG+ Sbjct: 1347 -----------PGPPGEPGPAGQ---------------------------DGPPGDKGDD 1368 Query: 1447 GTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 G PG G GP G PG GPPG RG G G +G Q G + + P Sbjct: 1369 GEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPP 1419 Score = 472 bits (1215), Expect = e-132 Identities = 370/1086 (34%), Positives = 438/1086 (40%), Gaps = 279/1086 (25%) Query: 563 GNLRGSPGPKGDM----------GSPGPKGDRGFPGTPGIPGP---LGHPGPQGPKGQKG 609 G RG G KG+ G PGP+G G PG PG GP +G PG +GP G+ G Sbjct: 446 GGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPG 505 Query: 610 SVGDPGMEGPMGQR----GREGPMGPRGEAGPPGSGEKGERGAA---------GEPGPHG 656 G G+ GP G R G G G GP S ++ + A G GP G Sbjct: 506 LPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMG 565 Query: 657 PPGVPGSVGPKGSSGSPGP------------QGPPGPVGLQGLRGE-------------- 690 G PG VGP GS G G QGPPGP G G RG Sbjct: 566 LTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTG 625 Query: 691 ----------VGLPGVK---GDKGPMGPPGPKGDQGEK------GPRGLTGEPGMRGLPG 731 GLPG K GD GP GPPGP GD GE+ GPRGL GEPG RGL G Sbjct: 626 PKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLG 685 Query: 732 AVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQ------- 784 G PG G G G DG GP+G G G P GPPG G+PG GL GPQ Sbjct: 686 PKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEP---GPPGQQGNPGAQGLPGPQGAIGPPG 742 Query: 785 --GPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAG 842 GP G PG PG PG G PG PGK GPPG G GPPGP G G G Sbjct: 743 EKGPLGKPGLPGMPGADGPPGHPGK------------EGPPGEKGGQGPPGPQGPIGYPG 790 Query: 843 PAGLPGHQEVLNLQGPP------------------------GPPGPRGPPGPSIP----- 873 P G+ G + L+G GPPGPRG GP P Sbjct: 791 PRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGG 850 Query: 874 --GPPGPRGPPGE----GLPGPPGPPGSFLSNSETFLSGPP---------GPPGPPGPKG 918 G PGP GPPGE G+PG PG PG G P G PG PGP+G Sbjct: 851 PNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRG 910 Query: 919 DQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPP---GPPGPQGP---KGDKGDPGVPG 972 +GP GPRG +G +G+ G +S G GPP GP GPQGP G KG PG PG Sbjct: 911 QRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPG 970 Query: 973 ALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLS 1032 G+P P + G + +GPPGPPG GP G +G Sbjct: 971 KDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGP-------------------M 1011 Query: 1033 GVQGPPGPPGPPGP--VTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAV 1090 G +G PGPPGPPG + + G+ + + + G+ F + Sbjct: 1012 GERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPG-KDGPPGLRGFPGDRGLPGPVGA 1070 Query: 1091 LQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGP 1150 L L G GPPGPPG +G + + IG+PG Sbjct: 1071 LG-----------LKGNEGPPGPPGPAGSPGERG-------------PAGAAGPIGIPGR 1106 Query: 1151 PGPPGLPGTSYEELLSLLRGSE-------FRGIVGPPGPPGPPGIPGNVWSSISVEDLSS 1203 PGP G PG + E+ +G + +G VG PGP GP G PG + + Sbjct: 1107 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGE-PG 1165 Query: 1204 YLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFI 1263 + G GPPGP GP GP G PG SGA E + L R F Sbjct: 1166 QKGSKGDKGEQGPPGPTGPQGPIGQPGPSGA----DGEPGPRGQQGLFGQKGDEGPRGF- 1220 Query: 1264 VGPPGPPGPQ---GPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGS 1320 GPPGP G Q GPPG+ S G+ G G G+ Sbjct: 1221 PGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGA 1280 Query: 1321 LGAGGAFGEAA-----GDRGPYGT--------DIGPGGGYGAAAEGGMYAGNGGLLGA-- 1365 +G G GEA G+ GP G + GP G G G G+ G G+ Sbjct: 1281 VGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGP-PGDDGPKGSPG 1339 Query: 1366 --DFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGP---QGPPGISKVFSAYS 1420 F GD GPPG+PGP GPPG Sbjct: 1340 PVGFPGD---------------------------PGPPGEPGPAGQDGPPG--------- 1363 Query: 1421 NVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKG 1480 +G G+ G+ G+PGP G+ GP+GPPG GPPGP G +G +G+KG Sbjct: 1364 ---------------DKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKG 1408 Query: 1481 DQVYAG 1486 + AG Sbjct: 1409 AKGEAG 1414 Score = 427 bits (1098), Expect = e-119 Identities = 278/694 (40%), Positives = 326/694 (46%), Gaps = 79/694 (11%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGRE 626 G PGP+G G GP+G+RG G G PGP G+ G GP G G G G +GP G G + Sbjct: 904 GKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPK 963 Query: 627 GPMGPRGEAGPPGS-GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQ 685 GP GP G+ G PG G++GE G G+ GP GPPGV G GP G +G G +G PGP G Sbjct: 964 GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPP 1023 Query: 686 GLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPA 745 G E GLPG+ G +G G PGP G G+ GP GL G PG RGLPG VG G KG GP Sbjct: 1024 G---EQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPP 1080 Query: 746 GPDGHQGPRGEQG---------LTGMPGIRGPPGPSGDPGKPGLTGPQGPQG-------- 788 GP G G GE+G + G PG +GPPGP+G+ G PG GPQGP G Sbjct: 1081 GPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPV 1140 Query: 789 -LPGT------PGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGA---P 838 LPG PG G KGE G PG+ + PGP GP G +G PGP GA P Sbjct: 1141 GLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEP 1200 Query: 839 GPAG------------PAGLPGHQEVLNLQGPPGPPGPRGPPGP----SIPGPPGPRGPP 882 GP G P G PG + LQG PGPPG +G G PGPPGPRGP Sbjct: 1201 GPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPS 1260 Query: 883 GE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSG 941 G G GP GPPG + G PG G PG G+ GPPGP+G +GE+G G S Sbjct: 1261 GAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPS--- 1317 Query: 942 SSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPP 1001 G GPPGP+GP GD G G PG +G P P G GPPG G Sbjct: 1318 ---------GAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDD 1368 Query: 1002 GPPGSISSSGQEIQQYIS--------------EYMQSDSIRSYLSGVQGPPGPPGPPGPV 1047 G PG S G + S E Q + +G++GPPG GP GP Sbjct: 1369 GEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQ 1428 Query: 1048 TTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQY--LM 1105 D V G L L+ D + + + L+ Sbjct: 1429 GAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLI 1488 Query: 1106 GPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELL 1165 G GPPG G GD L + SG IG PGPPG PG PG + Sbjct: 1489 GLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSG-PIGPPGPPGLPGPPGPKGAKGS 1547 Query: 1166 SLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVE 1199 S G +G G PGPPGPPG PG V + ++ Sbjct: 1548 SGPTGP--KGEAGHPGPPGPPGPPGEVIQPLPIQ 1579 Score = 400 bits (1029), Expect = e-111 Identities = 240/549 (43%), Positives = 270/549 (49%), Gaps = 81/549 (14%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGH---------PGPQGPKGQKGSVGDPGM 616 +G PGP G G GP G RGFPG G+PGP+G PGP GP G G G G Sbjct: 1038 KGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGA 1097 Query: 617 EGPMGQRGREGPMGPRGEAGPPGS-GEKGERGAAGEPGPHGPPGVPGSVGP--------- 666 GP+G GR GP GP G AG G+ GEKG +G AG G GP G+PG GP Sbjct: 1098 AGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGD 1157 Query: 667 ---------KGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGP 717 KGS G G QGPPGP G QG G+ G G G+ GP G G G +G++GP Sbjct: 1158 KGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGP 1217 Query: 718 RGLTGEP---GMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGD 774 RG G P G++GLPG GE G G +G GP G GPRG G G G +GPPG G+ Sbjct: 1218 RGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGN 1277 Query: 775 PGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGP--- 831 PG G G G G PG PG G G G G+ S S PGP GPPG GP Sbjct: 1278 PGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGS 1337 Query: 832 ---------PGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPP 882 PGPPG PGPAG G PG + G G PGP G PGPS GPPG RGPP Sbjct: 1338 PGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPS--GPPGKRGPP 1395 Query: 883 GEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQ------GEQGLPG 936 G GP G G + E L GPPG GP GP+G G PGP G + GEQGLPG Sbjct: 1396 GPA--GPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPG 1453 Query: 937 FSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIP-----------------SG 979 + G PG G GPKG+KG PG+ G +G P SG Sbjct: 1454 SPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSG 1513 Query: 980 P-SEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPP 1038 P E G + GPPGPPG PGPPG + G + +G GPP Sbjct: 1514 PKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGS----------SGPTGPKGEAGHPGPP 1563 Query: 1039 GPPGPPGPV 1047 GPPGPPG V Sbjct: 1564 GPPGPPGEV 1572 Score = 254 bits (650), Expect = 3e-67 Identities = 136/264 (51%), Positives = 152/264 (57%), Gaps = 22/264 (8%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGP---QGPKGQKGSVGDPGMEGPMGQR 623 G PGPKG G GPKG G G PG PGP G PGP GP G KG G+PG G G Sbjct: 1321 GPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPT 1380 Query: 624 GREGPMGPRGEAGPPG----SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGP---Q 676 G GP GP G+ GPPG G +GE+GA GE G GPPG G +GP+G+ G PGP + Sbjct: 1381 GEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLR 1440 Query: 677 GPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEP 736 G PGPVG QGL G PG G GPMGPPG G +G+ GP+G G PG+ GL G GE Sbjct: 1441 GIPGPVGEQGLPGS---PGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQ 1497 Query: 737 GAKGAMGPAGPDGHQGPRGEQGLTGM---------PGIRGPPGPSGDPGKPGLTGPQGPQ 787 G KG G GP G GP+GEQG+TG PG+ GPPGP G G G TGP+G Sbjct: 1498 GEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEA 1557 Query: 788 GLPGTPGRPGIKGEPGAPGKIVTS 811 G PG PG PG GE P I S Sbjct: 1558 GHPGPPGPPGPPGEVIQPLPIQAS 1581 Score = 209 bits (532), Expect = 2e-53 Identities = 161/489 (32%), Positives = 192/489 (39%), Gaps = 125/489 (25%) Query: 671 GSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLP 730 G P P P G E+ P D P P +G G E +R L Sbjct: 360 GEENPDQPTDP----GAGAEI--PTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLD 413 Query: 731 GAVGEP-----GAKGAMGPAGP-------DGHQGPRGEQGLTGMPG-------IRGPPGP 771 +P + +GP P +G GPRGE+G G P I GPPGP Sbjct: 414 ENYYDPYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGP 473 Query: 772 SGD---PGKPGLTGP---------QGPQGLPGTPGRPGIKGEP----------------G 803 G PG PG GP +GP G PG PG G+ G P G Sbjct: 474 EGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAG 533 Query: 804 APGKIVTSEGSSMLTV--------------------PGPPGPPGA---------MGPPGP 834 + G +V+++ S + PGP GPPG+ +GP GP Sbjct: 534 SKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGP 593 Query: 835 PGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGP----------------SIPGPPGP 878 G GP GPAG PG + G G PG GP G PGP GP Sbjct: 594 RGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGP 653 Query: 879 RGPPGE-------------GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGP 925 GPPG+ GLPG PGP G GPPGPPGPPG G G PGP Sbjct: 654 PGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGP------KGPPGPPGPPGVTGMDGQPGP 707 Query: 926 RGHQGEQGLPGFSTSGSSSFGLNLQGPP---GPPGPQGPKGDKGDPGVPGALGIPSGPSE 982 +G+ G QG PG + L GP GPPG +GP G G PG+PGA G P P + Sbjct: 708 KGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGK 767 Query: 983 GGSSSTMYVSGPPGPPGP---PGPPGSISSSGQEIQQYISEYMQSDSIRSYLS--GVQGP 1037 G GPPGP GP PGP G + G + D + G++G Sbjct: 768 EGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGD 827 Query: 1038 PGPPGPPGP 1046 G GPPGP Sbjct: 828 RGEIGPPGP 836 Score = 163 bits (412), Expect = 1e-39 Identities = 185/672 (27%), Positives = 237/672 (35%), Gaps = 169/672 (25%) Query: 883 GEGLPGPPGPPGSFL----SNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFS 938 GE P P PG+ S ++T S P PP PG +G G E+ + Sbjct: 360 GEENPDQPTDPGAGAEIPTSTADTSNSSNPAPP--PG----EGADDLEGEFTEETIRNLD 413 Query: 939 ----------TSGSSSFGLNLQGPP-----GPPGPQGPKGDKGDPGV--PGALGIPSGPS 981 TS S G + G GP+G KG KG+P + PG Sbjct: 414 ENYYDPYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPG--------- 464 Query: 982 EGGSSSTMYVSGPPGPPGP---PGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPP 1038 M + GPPGP GP PGPPG++ +GQ G +GPP Sbjct: 465 -------MLIEGPPGPEGPAGLPGPPGTMGPTGQVGDP----------------GERGPP 501 Query: 1039 GPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQ 1098 G PG PG + G + ++ R G G S+ + Q + Sbjct: 502 GRPGLPG-ADGLPGPP------GTMLMLPFRFGGGG------DAGSKGPMVSAQESQAQA 548 Query: 1099 YLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPG 1158 L+Q + RGP GP G + G PGP GPPG G Sbjct: 549 ILQQARLALRGPAGPMGLT----------------------------GRPGPVGPPGSGG 580 Query: 1159 TSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWS--------SISVEDLSSYLHTAGL 1210 E +G RG+ GPPGP G PG G S + + AGL Sbjct: 581 LKGEPGDVGPQGP--RGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGL 638 Query: 1211 SFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPP 1270 G G PGP GP GPPG G E D P R ++GP GPP Sbjct: 639 PGEKGHRGDPGPSGPPGPPGDDG-------ERGDDGEVGPRGLPGEPGPRG-LLGPKGPP 690 Query: 1271 GPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGE- 1329 GP GPPG + + ++G+ + + G G G G G+ Sbjct: 691 GPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKP 750 Query: 1330 -------AAGDRGPYGTDIGPG--GGYGAAAEGGM--YAGNGGLLGAD------------ 1366 A G G G + PG GG G G Y G G+ GAD Sbjct: 751 GLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEK 810 Query: 1367 -------FAGDL----DYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKV 1415 F GD+ D E+ +G GP G PGP GPPG Sbjct: 811 GEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRG----GPNGDPGPLGPPGEKGK 866 Query: 1416 FSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGE 1475 + Y QGP G G G PG G++G G PG PGP G RG G Sbjct: 867 LG---------VPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGP 917 Query: 1476 KGDKGDQVYAGR 1487 +G++G + G+ Sbjct: 918 RGERGPRGITGK 929 Score = 133 bits (334), Expect = 1e-30 Identities = 72/150 (48%), Positives = 86/150 (57%), Gaps = 20/150 (13%) Query: 565 LRGSPGPKGDM---GSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMG 621 LRG PGP G+ GSPGP G G G PG+PG G GP+G KG G +G G G G Sbjct: 1439 LRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQG 1498 Query: 622 QRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGP 681 ++G G GP+G +GP GE+G G +G GP GPPG+PG GPKG+ GS GP GP Sbjct: 1499 EKGDRGLPGPQGSSGP--KGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGP--- 1553 Query: 682 VGLQGLRGEVGLPGVKGDKGPMGPPGPKGD 711 +GE G P GP GPPGP G+ Sbjct: 1554 ------KGEAGHP------GPPGPPGPPGE 1571 Score = 90.1 bits (222), Expect = 1e-17 Identities = 51/115 (44%), Positives = 55/115 (47%), Gaps = 29/115 (25%) Query: 565 LRGSPGPKGDMGSPG------------PKGDRGFPGTPGIPGPLGHPG---PQGPKGQKG 609 L+G GPKG+ G PG KGDRG PG G GP G G P GP G G Sbjct: 1472 LKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPG 1531 Query: 610 SVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSV 664 G PG GP G +G GP GP+GE AG PGP GPPG PG V Sbjct: 1532 PPGLPGPPGPKGAKGSSGPTGPKGE--------------AGHPGPPGPPGPPGEV 1572 Score = 75.9 bits (185), Expect = 3e-13 Identities = 114/451 (25%), Positives = 146/451 (32%), Gaps = 148/451 (32%) Query: 1082 ISSEDILAVLQRDDVRQYLRQYLMGPRGPPGP--PGASGDGSLLSLDYAELSSRILSYMS 1139 + SED DD+ Y G P P PGA AE+ + + Sbjct: 341 VPSEDYYTPSPYDDLT-----YGEGEENPDQPTDPGAG----------AEIPTSTADTSN 385 Query: 1140 SSGISIGLPGPP---GPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGP--PGIPGNVWS 1194 SS P PP G L G EE + L + + P P PG+P N Sbjct: 386 SSN-----PAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIGPGMPAN--- 437 Query: 1195 SISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYL 1254 +D + G GP G G +G P + Sbjct: 438 ----QD----------TIYEGIGGPRGEKGQKGEPAII---------------------- 461 Query: 1255 TSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTG 1314 + I GPPGP GP G PG Sbjct: 462 ---EPGMLIEGPPGPEGPAGLPGPP----------------------------------- 483 Query: 1315 GGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYN 1374 G++G G G+ G+RGP G PG G M +L F G D Sbjct: 484 ----GTMGPTGQVGDP-GERGPPGRPGLPGADGLPGPPGTML-----MLPFRFGGGGDAG 533 Query: 1375 ELAVRVS-ESMQRQGLLQGMAYTVQGPPG------QPGPQGPPGISKVFSAYSNVTADLM 1427 VS + Q Q +LQ ++GP G +PGP GPPG + +V Sbjct: 534 SKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGP--- 590 Query: 1428 DFFQTYGAIQGPPGQKGEMGT---------------PGPKGDRG------PAGPPGHPGP 1466 Q +QGPPG G+ G GPKGDRG G GH G Sbjct: 591 ---QGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGD 647 Query: 1467 PGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 PGP G G GD G++ G R + +P Sbjct: 648 PGPSGPPGPPGDDGERGDDGEVGPRGLPGEP 678 Score = 39.3 bits (90), Expect = 0.029 Identities = 21/43 (48%), Positives = 23/43 (53%), Gaps = 6/43 (13%) Query: 565 LRGSPGPKGDMGSPGPKGDRGF------PGTPGIPGPLGHPGP 601 L G PGPKG GS GP G +G PG PG PG + P P Sbjct: 1535 LPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLP 1577 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 496 bits (1278), Expect = e-140 Identities = 368/971 (37%), Positives = 423/971 (43%), Gaps = 151/971 (15%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGR 625 RG PG +G G+PGP G RG G G GP G GP GP G G+VG G GP G RG Sbjct: 304 RGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGS 363 Query: 626 EGPMGPRGEAGPPG----SGEKGERGAAGEPGP---HGPPGVPGSVGPKGSSGSPGPQGP 678 EGP G RGE GPPG +G G GA G+PG +G PG+ G+ G G+ G GPQGP Sbjct: 364 EGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGP 423 Query: 679 PGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGP------RGLTGEPGMRGLPGA 732 GP G +G GE G PG KGD G G PGP G QG GP RG GEPG GLPG Sbjct: 424 GGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGP 483 Query: 733 VGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGT 792 GE G G+ G G DG GP+G G G PG GP G G+ G+PG G G +GL G+ Sbjct: 484 PGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGS 543 Query: 793 PGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEV 852 PG PG G+ G PG +G PGPPGPPGA G G G PGP G AG PG Sbjct: 544 PGSPGPDGKTGPPGP-AGQDGR-----PGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGE 597 Query: 853 LNLQGPPGPPGP---------RGPPGPSIP----GPPGPRGPPG-EGLPGPPGPPGSFLS 898 + GPPG GP +GPPGP+ P G GP G PG +GLPGP GPPG Sbjct: 598 RGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGE--- 654 Query: 899 NSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGP 958 G PG G GD G PGP G +GE+G PG +QGPPGP GP Sbjct: 655 ---------AGKPGEQGVPGDLGAPGPSGARGERGFPGER---------GVQGPPGPAGP 696 Query: 959 QGP---------KGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISS 1009 +G KGD G PG PG+ G P G + GP G G GP G+ S Sbjct: 697 RGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGS 756 Query: 1010 SGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPG---------PPGPV--TTITGETFDYS 1058 G+ D +R L+G GPPGP G P GP T G D Sbjct: 757 PGK------------DGVRG-LTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRG 803 Query: 1059 ELASHVVSYLRTSGYGVSLFSSSISSEDILAVL-QRDDVRQYLRQYLMGPRGPPGPPGAS 1117 E G + F+ ++ + D GP GP GPPG Sbjct: 804 EPGPP----------GPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPI 853 Query: 1118 GDGSLLSLDYAELSSRILSYMSSSGIS--IGLPGPPG---PPGLPGTSYEELLSLLRGSE 1172 G+ A S+ G + +G PGP G PPG PG + +E RG Sbjct: 854 GNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGET 913 Query: 1173 FR----GIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGP 1228 G VGPPGPPGP G G+ + GP G PG PGP+G Sbjct: 914 GPAGRPGEVGPPGPPGPAGEKGSPGAD-------------------GPAGAPGTPGPQGI 954 Query: 1229 PGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPG------PPGPQGPPGDSRLL 1282 G G + F L P GP G PPGP GPPG L Sbjct: 955 AGQRGVVGLPGQRGERGFPG-----LPGPSGEPGKQGPSGASGERGPPGPMGPPG---LA 1006 Query: 1283 STDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGT--D 1340 R + + S R GS + G AG GA GA G A G GP G D Sbjct: 1007 GPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPG-APGPVGPAGKSGD 1065 Query: 1341 IGPGGGYGAAAEGGMYAGNGGLLGADFAGDL-DYNELAVRVSESMQRQGLLQGMAYTVQG 1399 G G G A G G GD + E R + + LQG G Sbjct: 1066 RGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPP----G 1121 Query: 1400 PPGQPGPQGPPGISKVFSAYS---NVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRG 1456 PPG PG QGP G S + A D GPPG +G G GP G G Sbjct: 1122 PPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPG 1181 Query: 1457 PAGPPGHPGPP 1467 P GPPG PGPP Sbjct: 1182 PPGPPGPPGPP 1192 Score = 495 bits (1274), Expect = e-139 Identities = 372/1037 (35%), Positives = 442/1037 (42%), Gaps = 193/1037 (18%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKG----------------QKG 609 +G GP+G G GP G G PG PG+PGP G PGP GP G G Sbjct: 114 KGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTG 173 Query: 610 SVGDPGMEGPMGQRGREGP---MGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGP 666 + PG GP G RG GP GP+G GPP GE GE GA+G GP GPPG PG G Sbjct: 174 GISVPGPMGPSGPRGLPGPPGAPGPQGFQGPP--GEPGEPGASGPMGPRGPPGPPGKNGD 231 Query: 667 KGSSGS---PGPQGPPGPVGLQGLRGEVGLPGVKGD---------KGPMGPPGPKGDQGE 714 G +G PG +GPPGP G +GL G GLPG+KG KG GP GPKG+ G Sbjct: 232 DGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGS 291 Query: 715 KGPRGLTGEPGMRGLPGAVGEP------------GAKGAMGPAGPDGHQGP--------- 753 G G G+ G RGLPG G P GA GA GP GP G GP Sbjct: 292 PGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGA 351 Query: 754 RGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEG 813 +GE G G G GP G G+PG PG G GP G PG G+PG KG GAPG I + G Sbjct: 352 KGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPG-IAGAPG 410 Query: 814 SSMLTVP----GPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPP------G 863 P GP GPPG G G PGAPG G G G + +QGPPGP G Sbjct: 411 FPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRG 470 Query: 864 PRGPPGPS-IPGPPGPRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQG 921 RG PGP+ +PGPPG RG PG G PG G G GP G G PGP G +G Sbjct: 471 ARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGP---------KGPAGERGSPGPAGPKG 521 Query: 922 PPGPRGHQGEQGLP---GFSTSGSSSFGLNLQGPPGP------PGPQGPKGDKGDPGVPG 972 PG G GE GLP G + S S GPPGP PGP GP G +G GV G Sbjct: 522 SPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMG 581 Query: 973 ALGIPSGPSEGGSSSTMYVSGPPGPPGP---------PGPPGSISSSGQEIQQYISEYMQ 1023 G E G + V GPPG GP GPPG +G+ +Q Sbjct: 582 FPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQG------ 635 Query: 1024 SDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSIS 1083 + G QG PGP GPPG GE +L + S R G F Sbjct: 636 ----PAGSPGFQGLPGPAGPPGEAGK-PGEQGVPGDLGAPGPSGAR----GERGFPG--- 683 Query: 1084 SEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGI 1143 + + GP GP GP GA+G D A+ + S G Sbjct: 684 -----------------ERGVQGPPGPAGPRGANG---APGNDGAKGDAGAPGAPGSQGA 723 Query: 1144 S--IGLPGPPGPPGLPGTSYEELLSLLRGSE-------FRGIVGPPGPPGPPGIPGNVWS 1194 G+PG G GLPG + + +G++ RG+ GP GPPGP G PG+ Sbjct: 724 PGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGE 783 Query: 1195 SISVEDLSSYLHTAGLSFIPGPPGPPGPPGP---RGPPGVSGALATYAAENSDSFRSELI 1251 S S G PG G PGPPGP GPPG G + + Sbjct: 784 S----GPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGD-- 837 Query: 1252 SYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSM 1311 GPPGP GP GPPG + + S+ ++ G++ Sbjct: 838 ------------AGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGP 885 Query: 1312 STGGGGAGSLGAGGAFGEAA-----GDRGPYGT--DIGPGGGYGAAAEGGMYAGNG--GL 1362 G AG G G G+ G+ GP G ++GP G G A E G +G G Sbjct: 886 PGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGA 945 Query: 1363 LGADFAGDLDYNELAVRVSESMQRQGL--LQGMAYT--VQGPP------GQPGPQGPPGI 1412 G + V + +G L G + QGP G PGP GPPG+ Sbjct: 946 PGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGL 1005 Query: 1413 SKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGP---PGHPGPPGP 1469 + A +G PG+ G G G +G+ GPAGP PG PG PGP Sbjct: 1006 AGPPGESGREGAP---------GAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGP 1056 Query: 1470 RGHKGEKGDKGDQVYAG 1486 G G+ GD+G+ AG Sbjct: 1057 VGPAGKSGDRGETGPAG 1073 Score = 495 bits (1274), Expect = e-139 Identities = 354/1005 (35%), Positives = 420/1005 (41%), Gaps = 203/1005 (20%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGH------------PGPQGPKGQKGSVGD- 613 G PG G+ G PGP+G RG PGT G+PG GH GP GPKG+ GS G+ Sbjct: 236 GKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGEN 295 Query: 614 -----------------PGMEGPMGQRGRE------GPMGPRGEAGPPG----------S 640 PG GP G RG + GP GP G AGPPG + Sbjct: 296 GAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEA 355 Query: 641 GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDK 700 G +G RG+ G G G PG PG G G +G+PG G PG G G G G PG G + Sbjct: 356 GPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGAR 415 Query: 701 GPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQ--- 757 GP GP GP G G KG G G PG +G GA GEPG G GP GP G +G RG + Sbjct: 416 GPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEP 475 Query: 758 ---GLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEP---GAPGKIVTS 811 GL G PG RG PG G PG G+ GP+GP G G+PG G KG P G PG+ Sbjct: 476 GPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLP 535 Query: 812 EGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS 871 + PG PGP G GPPGP G G GP G PG + + G PGP G G PG + Sbjct: 536 GAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA 595 Query: 872 ----IPGPPGPRGPPGE----GLPGPPGPPGSFLSNSETFLSGPP---GPPGPPGPKGDQ 920 +PGPPG GP G+ G GPPGP G E +G P G PGP GP G+ Sbjct: 596 GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEA 655 Query: 921 GPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGP 980 G PG +G G+ G PG S + +G GPPGP GP+G G PG GA G P Sbjct: 656 GKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAP 715 Query: 981 SEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGP 1040 GS + G PG G G PG G + D +R L+G GPPGP Sbjct: 716 GAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRG-LTGPIGPPGP 774 Query: 1041 PGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYL 1100 G PG GE+ T G Sbjct: 775 AGAPGD----KGESGPSGPAGP-------TGARGAP------------------------ 799 Query: 1101 RQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTS 1160 G RG PGPPG +G D + + G G PGP GP G PG Sbjct: 800 -----GDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKG-DAGPPGPAGPAGPPGPI 853 Query: 1161 YEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPP 1220 +G+ RG GPPG G PG G V GPPGP Sbjct: 854 GNVGAPGAKGA--RGSAGPPGATGFPGAAGRV----------------------GPPGPS 889 Query: 1221 GPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSR 1280 G GP GPPG +G E R E T P R VGPPGPPGP G G Sbjct: 890 GNAGPPGPPGPAG------KEGGKGPRGE-----TGPAGRPGEVGPPGPPGPAGEKG--- 935 Query: 1281 LLSTDASHSRGSSSSSHSSSV-----------RRGSSYSSSMSTGGGGAGSLGAGGAFGE 1329 S A G+ + + +RG + G G G G Sbjct: 936 --SPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSG---- 989 Query: 1330 AAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGL 1389 A+G+RGP G +GP G G E +G G GA+ + D + A Sbjct: 990 ASGERGPPG-PMGPPGLAGPPGE----SGREGAPGAEGSPGRDGSPGA------------ 1032 Query: 1390 LQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTP 1449 +G G+ GP GPPG A V GP G+ G+ G Sbjct: 1033 --------KGDRGETGPAGPPGAPGAPGAPGPV---------------GPAGKSGDRGET 1069 Query: 1450 GPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIA 1494 GP G GP GP G GP GP+G +G+KG+ G+Q G + R + Sbjct: 1070 GPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFS 1114 Score = 461 bits (1186), Expect = e-129 Identities = 355/980 (36%), Positives = 423/980 (43%), Gaps = 166/980 (16%) Query: 561 ENGNLRGSPGPKGDMGSPGPKGDRGFPG--TPGIPGPLGHPGPQGPKGQKGSVGDPGMEG 618 E N G+ P+G+ P G T G+ GP G GP+GP+G G PG +G Sbjct: 77 ETKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGP---AGPPGRDG 133 Query: 619 PMGQRGREGPMGPRGEAGPPGSGEK--GERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQ 676 GQ G GP GP G GPPG G + + G VPG +GP G G PGP Sbjct: 134 IPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPP 193 Query: 677 GPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEP 736 G PGP G QG GE G PG G GP GPPGP G G+ G G G PG RG PG Sbjct: 194 GAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGP---Q 250 Query: 737 GAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPG---LTGPQGPQGLPGTP 793 GA+G G AG G +G RG GL G G GP GP G+PG PG G GP+GLPG Sbjct: 251 GARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGER 310 Query: 794 GRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGA---PGPAGPAGLPGHQ 850 GRPG G GA G ++G++ GPPGP G GPPG PGA G AGP G G + Sbjct: 311 GRPGAPGPAGARG----NDGAT--GAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSE 364 Query: 851 EVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPG 909 ++G PGPPGP G GP+ G PG G PG +G G PG G+ G PG Sbjct: 365 GPQGVRGEPGPPGPAGAAGPA--GNPGADGQPGAKGANGAPGIAGA---------PGFPG 413 Query: 910 PPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFG----LNLQGPPGPPGPQGPKGDK 965 GP GP+G GPPGP+G+ GE G PG S + + G + +QGPPGP G +G +G + Sbjct: 414 ARGPSGPQGPGGPPGPKGNSGEPGAPG-SKGDTGAKGEPGPVGVQGPPGPAGEEGKRGAR 472 Query: 966 GDP---GVPGALGIPSGPSEGGSSSTMYVSGPPGP------PGPPGPPGSISSSGQEIQQ 1016 G+P G+PG G GP G V+GP GP PGP GP GS +G+ + Sbjct: 473 GEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEA 532 Query: 1017 YI--SEYMQSDSIRSYLSGVQGPPGP------PGPPGPVTTITGET----FDYSELASHV 1064 + ++ + G GPPGP PGPPGP G+ F + A+ Sbjct: 533 GLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGP-PGARGQAGVMGFPGPKGAAGE 591 Query: 1065 VSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLS 1124 G + + +D A Q GP GP GP G G+ Sbjct: 592 PGKAGERGVPGPPGAVGPAGKDGEAGAQ-------------GPPGPAGPAGERGE----- 633 Query: 1125 LDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELL---------SLLRGSE--- 1172 S G GLPGP GPPG G E+ + S RG Sbjct: 634 ----------QGPAGSPGFQ-GLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFP 682 Query: 1173 -FRGIVGPPGPPGP---PGIPGN--VWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPR 1226 RG+ GPPGP GP G PGN GL +PG G G PGP+ Sbjct: 683 GERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPK 742 Query: 1227 GPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDA 1286 G G +G + D R + GP GPPGP G PGD Sbjct: 743 GDRGDAGPKGADGSPGKDGVRG--------------LTGPIGPPGPAGAPGDK---GESG 785 Query: 1287 SHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGG 1346 + + + RG + G G+ G GA GE GD G G D GP G Sbjct: 786 PSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGE-PGDAGAKG-DAGPPGP 843 Query: 1347 YGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGP 1406 G A G GN G GA A R S G A V GPPG G Sbjct: 844 AGPAGPPGP-IGNVGAPGAKGA----------RGSAGPPGATGFPGAAGRV-GPPGPSGN 891 Query: 1407 QGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGP 1466 GPP GPPG G+ G GP+G+ GPAG PG GP Sbjct: 892 AGPP---------------------------GPPGPAGKEGGKGPRGETGPAGRPGEVGP 924 Query: 1467 PGPRGHKGEKGDKGDQVYAG 1486 PGP G GEKG G AG Sbjct: 925 PGPPGPAGEKGSPGADGPAG 944 Score = 428 bits (1101), Expect = e-119 Identities = 297/786 (37%), Positives = 351/786 (44%), Gaps = 127/786 (16%) Query: 559 EQENGNLRGSPGPKGDMGSPGPK---GDRGFPGTPGIPGP------LGHPGPQGPKGQKG 609 E+ RG PGP G G PG + G RGFPG G+ GP G PGP GPKG G Sbjct: 465 EEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPG 524 Query: 610 SVGDP---GMEGPMGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVG 665 G P G+ G G G G GP G+ GPPG +G+ G G G PG G GV G G Sbjct: 525 EAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPG 584 Query: 666 PKGSSGSP---GPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTG 722 PKG++G P G +G PGP G G G+ G G +G GP GP G +G+QG G G G Sbjct: 585 PKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQG 644 Query: 723 EPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTG 782 PG G PG G+PG +G G G G G RGE+G G G++GPPGP+G G G G Sbjct: 645 LPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPG 704 Query: 783 PQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAP---- 838 G +G G PG PG +G PG G + G++ L PGP G G GP G G+P Sbjct: 705 NDGAKGDAGAPGAPGSQGAPGLQG-MPGERGAAGL--PGPKGDRGDAGPKGADGSPGKDG 761 Query: 839 --------GPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG----PSIPGPPGPRGPPG-EG 885 GP GPAG PG + GP GP G RG PG P PGP G GPPG +G Sbjct: 762 VRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADG 821 Query: 886 LPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSF 945 PG G PG + + GP GP GPPGP G+ G PG +G +G G PG +T + Sbjct: 822 QPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPG-ATGFPGAA 880 Query: 946 G-------LNLQGPPGPPGP------QGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVS 992 G GPPGPPGP +GP+G+ G G PG +G P P G + Sbjct: 881 GRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGAD 940 Query: 993 GPPGPPGPPGPP------GSISSSGQEIQQYI-----SEYMQSDSIRSYLSGVQGPPGPP 1041 GP G PG PGP G + GQ ++ S SG +GPPGP Sbjct: 941 GPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPM 1000 Query: 1042 GPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLR 1101 GPPG LA R G S A R + Sbjct: 1001 GPPG--------------LAGPPGESGREGAPGAEGSPGRDGSPG--AKGDRGET----- 1039 Query: 1102 QYLMGPRGPPGPPGASGDGSLL-----SLDYAELSSRILSYMSSSGISIGLPGPPGPPGL 1156 GP GPPG PGA G + S D E + + G GP GP G Sbjct: 1040 ----GPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGD 1095 Query: 1157 PGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGP 1216 G + E+ ++G RG G GPPGPPG PG GP Sbjct: 1096 KGETGEQGDRGIKG--HRGFSGLQGPPGPPGSPGE----------------------QGP 1131 Query: 1217 PGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFI-----VGPPGPPG 1271 G GP GPRGPPG +G A D L + P R VGPPGPPG Sbjct: 1132 SGASGPAGPRGPPGSAG------APGKDGLNG-LPGPIGPPGPRGRTGDAGPVGPPGPPG 1184 Query: 1272 PQGPPG 1277 P GPPG Sbjct: 1185 PPGPPG 1190 Score = 425 bits (1092), Expect = e-118 Identities = 285/715 (39%), Positives = 330/715 (46%), Gaps = 112/715 (15%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGP------LGHPGPQGPKGQKGSVGDPGMEGPM 620 GSPGP G G PGP G G PG PG PG +G PGP+G G+ G G+ G+ GP Sbjct: 545 GSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPP 604 Query: 621 GQRGREGPMGPRGEAGPPG----SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQ 676 G G G G G GPPG +GE+GE+G AG PG G +PG GP G +G PG Q Sbjct: 605 GAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQG---LPGPAGPPGEAGKPGEQ 661 Query: 677 GPPGPVGL---QGLRGEVGLPGVKGDKGPMGPPGP------------KGDQGEKGPRGLT 721 G PG +G G RGE G PG +G +GP GP GP KGD G G G Sbjct: 662 GVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQ 721 Query: 722 GEPGMRGLPG---AVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKP 778 G PG++G+PG A G PG KG G AGP G G G+ G+ G+ G GPPGP+G PG Sbjct: 722 GAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDK 781 Query: 779 GLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAP 838 G +GP GP G G G PG +GEPG PG + PG G PG G G G P Sbjct: 782 GESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPP 841 Query: 839 GPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS-IPGPPGPRGPPG-EGLPGPPGPPGSF 896 GPAGPAG PG + G G G GPPG + PG G GPPG G GPPGPPG Sbjct: 842 GPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPA 901 Query: 897 LSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPP 956 GP G GP G G+ GPPGP G GE+G PG G PG P Sbjct: 902 GKEGG---KGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPA---------GAPGTP 949 Query: 957 GPQGPKGDKGDPGVPGALGI--------PSG-PSEGGSSSTMYVSGPPGPPGPPGPPGSI 1007 GPQG G +G G+PG G PSG P + G S GPPGP GPPG G Sbjct: 950 GPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPP 1009 Query: 1008 SSSGQEIQQYI--------SEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSE 1059 SG+E S + D + +G G PG PG PGPV G++ D E Sbjct: 1010 GESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGP-AGKSGDRGE 1068 Query: 1060 LASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGD 1119 G + + + +G RGP GP G GD Sbjct: 1069 T-------------GPAGPAGPVGP--------------------VGARGPAGPQGPRGD 1095 Query: 1120 GSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGP 1179 + E R + G S GL GPPGPPG PG S G GP Sbjct: 1096 KG----ETGEQGDRGIK--GHRGFS-GLQGPPGPPGSPGEQGPSGAS--------GPAGP 1140 Query: 1180 PGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGA 1234 GPPG G PG + + G + GP GPPGPPGP GPPG A Sbjct: 1141 RGPPGSAGAPGKDGLN-GLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSA 1194 Score = 278 bits (712), Expect = 2e-74 Identities = 166/392 (42%), Positives = 189/392 (48%), Gaps = 75/392 (19%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGI---PGPLGHPGPQGPKGQKGSVGDPGMEGPMGQR 623 G PG KG+ G G KGD G PG G PGP+G+ G G KG +GS G PG G G Sbjct: 821 GQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAA 880 Query: 624 GREGPMGPRGEAGPPG----------SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSP 673 GR GP GP G AGPPG G +GE G AG PG GPPG PG G KGS G+ Sbjct: 881 GRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGAD 940 Query: 674 GPQGPPG---PVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGE------- 723 GP G PG P G+ G RG VGLPG +G++G G PGP G+ G++GP G +GE Sbjct: 941 GPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPM 1000 Query: 724 -----------------------PGMRGLPGAVGE------------PGAKGAMGPAGPD 748 PG G PGA G+ PGA GA GP GP Sbjct: 1001 GPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPA 1060 Query: 749 GHQGPRGEQGLTGMPG------IRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEP 802 G G RGE G G G RGP GP G G G TG QG +G+ G G G++G P Sbjct: 1061 GKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPP 1120 Query: 803 GAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGP------PGAPGPAGPAGLPGHQEVLNLQ 856 G PG S GP GPPG+ G PG PG GP GP G G + Sbjct: 1121 GPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPP 1180 Query: 857 GPPGPPGPRGPPGPS-----IPGPPGPRGPPG 883 GPPGPPGP GPP +P PP + G Sbjct: 1181 GPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDG 1212 Score = 234 bits (596), Expect = 6e-61 Identities = 221/698 (31%), Positives = 256/698 (36%), Gaps = 159/698 (22%) Query: 820 PGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPR 879 PG P G P P G+ P QE ++GP G GPRGP GP+ GPPG Sbjct: 82 PGAEVPEGECCPVCPDGSESPTD-------QETTGVEGPKGDTGPRGPRGPA--GPPGRD 132 Query: 880 GPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFST 939 G PG+ PG PGPPG PPGPPGPPG G+ P G+ + ST Sbjct: 133 GIPGQ--PGLPGPPG------------PPGPPGPPGLGGNFAPQLSYGYDEK------ST 172 Query: 940 SGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPG 999 G S PGP GP GP+G G PG PG G P E G SGP GP G Sbjct: 173 GGISV--------PGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGA---SGPMGPRG 221 Query: 1000 PPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGP------PGPPGPVTTITGE 1053 PPGPPG G+ + + G +GPPGP PG G Sbjct: 222 PPGPPGKNGDDGE-------------AGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHR 268 Query: 1054 TFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGP 1113 F + A G S + + MGPRG PG Sbjct: 269 GFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQ-------------------MGPRGLPGE 309 Query: 1114 ---PGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGT---SYEELLSL 1167 PGA G D A + + G GP GPPG PG E Sbjct: 310 RGRPGAPGPAGARGNDGA----------TGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQG 359 Query: 1168 LRGSEF-RGIVGPPGPPGPPGIPGNVWS-----SISVEDLSSYLHTAGLSFIPGPPGPPG 1221 RGSE +G+ G PGPPGP G G + + + AG PG GP G Sbjct: 360 PRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSG 419 Query: 1222 PPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRL 1281 P GP GPPG G A S G PGP G QGPPG + Sbjct: 420 PQGPGGPPGPKGNSGEPGAPGSKGDTGAK--------------GEPGPVGVQGPPGPA-- 463 Query: 1282 LSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGT-- 1339 + G + GG GS G GA G AG +GP G Sbjct: 464 ----------GEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADG-VAGPKGPAGERG 512 Query: 1340 DIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQG 1399 GP G G+ E G G GL GA S + G A G Sbjct: 513 SPGPAGPKGSPGEAGR-PGEAGLPGAK-------GLTGSPGSPGPDGKTGPPGPA----G 560 Query: 1400 PPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAG 1459 G+PGP GPPG + + G PG KG G PG G+RG G Sbjct: 561 QDGRPGPPGPPGA------------------RGQAGVMGFPGPKGAAGEPGKAGERGVPG 602 Query: 1460 PPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 PPG GP G G G +G G AG R + A P Sbjct: 603 PPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSP 640 Score = 219 bits (558), Expect = 2e-56 Identities = 124/272 (45%), Positives = 135/272 (49%), Gaps = 47/272 (17%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGR 625 RG PG G G PG +G G G G PGP+G PG GP G+ G G PG EG G+ G Sbjct: 970 RGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGS 1029 Query: 626 EGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQ 685 G G RGE GP AG PG G PG PG VGP G SG G GP GP Sbjct: 1030 PGAKGDRGETGP-----------AGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPA--- 1075 Query: 686 GLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPA 745 G VG G +G GP GP G KG+ GE+G RG+ G G GL G G PG+ G GP+ Sbjct: 1076 ---GPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPS 1132 Query: 746 GPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAP 805 G G GP RGPPG +G PGK GL G GP G PG GR G G G P Sbjct: 1133 GASGPAGP------------RGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPP 1180 Query: 806 GKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGA 837 G PPGPP GPPGPP A Sbjct: 1181 G---------------PPGPP---GPPGPPSA 1194 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 495 bits (1275), Expect = e-139 Identities = 361/982 (36%), Positives = 430/982 (43%), Gaps = 171/982 (17%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGRE 626 G PG G G+ G +G G PG PG PG G PG G KG+ G G PG G GQRG Sbjct: 312 GLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEP 371 Query: 627 GPMG---PRGEAGPPG----SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPP 679 GP G +G GPPG G KGE G AG PG G G G GP G++G+PG +G Sbjct: 372 GPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGA 431 Query: 680 GPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAK 739 G G G +GE PG +G++G G PG G +GE G G GEPG GLPGA GE GA Sbjct: 432 GEPGKNGAKGE---PGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAP 488 Query: 740 GAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIK 799 G GPAGP+G G +G G G PG GP G +G+PG+ G+ G G +G+PG+PG PG Sbjct: 489 GFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSD 548 Query: 800 GEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPP 859 G+PG PG S+G S PGPPGP G G PG G PGP G G PG +G P Sbjct: 549 GKPGPPG----SQGES--GRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKN---GERGGP 599 Query: 860 GPPGPRGPPGPS----IPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPP---GPP 911 G PGP+GPPG + GPPGP GP G+ G GPPGP G GPP G P Sbjct: 600 GGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQG---LQGLPGTGGPPGENGKP 656 Query: 912 GPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVP 971 G PGPKGD G PG G +G+ G PG + L+G GPPGP+G KG G PG P Sbjct: 657 GEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPP 716 Query: 972 GALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYL 1031 GA G P G + GP G G PG PG+ G++ Sbjct: 717 GAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKD------------------ 758 Query: 1032 SGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVL 1091 G +GP GP GPPGP G+ D E G+ + S Sbjct: 759 -GPRGPTGPIGPPGP----AGQPGDKGE----------GGAPGLPGIAGPRGSPG----- 798 Query: 1092 QRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPP 1151 +R + GP GP G PGA G + R G G+ GPP Sbjct: 799 ERGET---------GPPGPAGFPGAPGQNG----EPGGKGERGAPGEKGEGGPPGVAGPP 845 Query: 1152 GPPGLPGTSYEELLSLLRGSE----------FRGIVGP------PGPPGPPGIPG----- 1190 G G G + + RGS RG+ GP PGPPGP G PG Sbjct: 846 GGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPP 905 Query: 1191 ------NVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSD 1244 S V G PG GPPG PGP G G++GA Sbjct: 906 GPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMP 965 Query: 1245 SFRS----ELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSS 1300 R + + + + + G GPPGPQG PG L T R + S Sbjct: 966 GPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPG---LAGTAGEPGRDGNPGSDGLP 1022 Query: 1301 VRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNG 1360 R GS G G G G+ GA G A G GP G +GP G G E G AG Sbjct: 1023 GRDGS------PGGKGDRGENGSPGAPG-APGHPGPPG-PVGPAGKSGDRGESGP-AGPA 1073 Query: 1361 GLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPG-ISKVFSAY 1419 G G G G PGPQGP G + Sbjct: 1074 GAPGP--------------------------------AGSRGAPGPQGPRGDKGETGERG 1101 Query: 1420 SNVTADLMDFFQTYGA--IQGPPGQKGEMGTPGPKGDRGPAGPPGHP------------G 1465 + F GA GP GQ+G +G+PGP G RGP GP G P G Sbjct: 1102 AAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIG 1161 Query: 1466 PPGPRGHKGEKGDKGDQVYAGR 1487 PPGPRG++GE+G +G + G+ Sbjct: 1162 PPGPRGNRGERGSEGSPGHPGQ 1183 Score = 489 bits (1259), Expect = e-138 Identities = 359/965 (37%), Positives = 411/965 (42%), Gaps = 153/965 (15%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGH---PGPQGPKGQKGSVGDPGMEGPMGQR 623 G G KG+ G+PG KG+ G PG G PGP+G PG +G G G+ G G +G G Sbjct: 270 GRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSD 329 Query: 624 GREGPMGPRGEAGPPGS-GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPV 682 G+ GP GP G AG PGS G KGE G AG PG +G PG G GP+G +G+ GP GPPG Sbjct: 330 GQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGIN 389 Query: 683 GLQGLRGEVG---LPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAK 739 G G +GE+G +PG G G GPPGP G G G RG GEPG G G G G + Sbjct: 390 GSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGER 449 Query: 740 GAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIK 799 G G G G +G G+ G G PG G PG +G+ G PG GP GP G+PG G G + Sbjct: 450 GEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGER 509 Query: 800 GEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPP 859 G PG G + G PG PG G PG PG PG G G PG Q GPP Sbjct: 510 GAPGPAGPRGAAGEPGR---DGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPP 566 Query: 860 GPPGPRGPPGP-SIPGPPGPRGPPGE-------GLPGPPGPPGSFLSNSETFLSGPPGPP 911 GP GPRG PG PGP G G PG+ G PGP GPPG N ET GPPGP Sbjct: 567 GPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGK---NGETGPQGPPGPT 623 Query: 912 GPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGP---PGPQGPKGDKGDP 968 GP G KGD GPPGP QG QGLPG GPPG PG GPKGD G P Sbjct: 624 GPGGDKGDTGPPGP---QGLQGLPGTG------------GPPGENGKPGEPGPKGDAGAP 668 Query: 969 GVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIR 1028 G PG G P E G G G GPPGP G Sbjct: 669 GAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGG---------------------- 706 Query: 1029 SYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDIL 1088 G GPPGPPG G + G + L S G Sbjct: 707 ---KGAAGPPGPPGAAG-TPGLQGMPGERGGLGSP----------GPKGDKGEPGGPGAD 752 Query: 1089 AVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLP 1148 V +D R GP GPPGP G GD G + GLP Sbjct: 753 GVPGKDGPRGPT-----GPIGPPGPAGQPGD-------------------KGEGGAPGLP 788 Query: 1149 GPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSS--YLH 1206 G GP G PG RG GPPGP G PG PG + + Sbjct: 789 GIAGPRGSPGE--------------RGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKG 834 Query: 1207 TAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGP 1266 G + GPPG GP GP GP GV G + + F L P + GP Sbjct: 835 EGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGA--RGLPGPPGSNGNPGP 892 Query: 1267 PGP---PGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGA 1323 PGP PG GPPG + +T A S G S + + G S G G LG Sbjct: 893 PGPSGSPGKDGPPGPAG--NTGAPGSPGVSGPKGDAG-QPGEKGSPGAQGPPGAPGPLGI 949 Query: 1324 GGAFGEAAGDRGPYGTDIGPGGG---YGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRV 1380 G G A G GP G GP G G E G NG +G+ Sbjct: 950 AGITG-ARGLAGPPGMP-GPRGSPGPQGVKGESGKPGANG------LSGERG-------- 993 Query: 1381 SESMQRQGLLQGMAYTVQGP--PGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQG 1438 QGL G+A T P G PG G PG + + G Sbjct: 994 --PPGPQGL-PGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPG 1050 Query: 1439 PPGQKGEMGTPGPKGDRGPAGPPGHPGP------PGPRGHKGEKGDKGDQVYAGRRRRRS 1492 PPG G G G +G+ GPAGP G PGP PGP+G +G+KG+ G++ AG + R Sbjct: 1051 PPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRG 1110 Query: 1493 IAVKP 1497 P Sbjct: 1111 FPGNP 1115 Score = 489 bits (1258), Expect = e-137 Identities = 360/1022 (35%), Positives = 414/1022 (40%), Gaps = 175/1022 (17%) Query: 563 GNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHP------GPQGPKGQKGSVGDPGM 616 G L G PGP G G PGP G G PG+PG PG G P GP GP G G++G G Sbjct: 167 GGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGP 226 Query: 617 EGPMGQRGREGPMGPRGEAGPPG----------------------SGEKGERGAAGEPGP 654 G G+ GR G G RG GPPG +GEKGE GA G G Sbjct: 227 AGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGE 286 Query: 655 HGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGP--------- 705 +G PG G+ GP G G+PG +G PG G G RG G G G GP GP Sbjct: 287 NGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGS 346 Query: 706 PGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMP-- 763 PG KG+ G G G G PG RG PG G GA+G GP G +G G +GE G G+P Sbjct: 347 PGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGA 406 Query: 764 ----GIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGE------PGAPGKIVTSEG 813 G RGPPGP+G G PGL G G G G G PG +GE PG PG Sbjct: 407 PGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGK 466 Query: 814 SSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG---- 869 PG G PGA G G PG GPAGP G+PG + +G PGP GPRG G Sbjct: 467 DGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGR 526 Query: 870 PSIPGPPGPRGPPGE----GLPGPPGPPGSFLSNSETFLSGPPGPPGP---------PGP 916 +PG PG RG PG G G PGPPG S E+ GPPGP GP PGP Sbjct: 527 DGVPGGPGMRGMPGSPGGPGSDGKPGPPG---SQGESGRPGPPGPSGPRGQPGVMGFPGP 583 Query: 917 KGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGI 976 KG+ G PG G +G G PG + QGPPGP GP G KGD G PG G G+ Sbjct: 584 KGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGL 643 Query: 977 PSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYL----- 1031 P G + GP G G PG PG +G ++ + +R Sbjct: 644 PGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGP 703 Query: 1032 SGVQGPPGPPGPPGPVTT--ITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILA 1089 G +G GPPGPPG T + G + L S G Sbjct: 704 EGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSP----------GPKGDKGEPGGPGADG 753 Query: 1090 VLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPG 1149 V +D R GP GPPGP G GD G + GLPG Sbjct: 754 VPGKDGPRG-----PTGPIGPPGPAGQPGD-------------------KGEGGAPGLPG 789 Query: 1150 PPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVW--SSISVEDLSSYLHT 1207 GP G PG RG GPPGP G PG PG Sbjct: 790 IAGPRGSPGE--------------RGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGE 835 Query: 1208 AGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPP 1267 G + GPPG GP GP GP GV G + + F L P + GPP Sbjct: 836 GGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPG--ARGLPGPPGSNGNPGPP 893 Query: 1268 GP---PGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAG 1324 GP PG GPPG + S +GS + G G G Sbjct: 894 GPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGIT 953 Query: 1325 GAFGEAA--------GDRGPYGT--DIGPGGGYGAAAEGGM--------YAGNGGLLGAD 1366 GA G A G GP G + G G G + E G AG G G D Sbjct: 954 GARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRD 1013 Query: 1367 FAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADL 1426 G+ + L R + + + G PG PGP GP G + Sbjct: 1014 --GNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPA------------- 1058 Query: 1427 MDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 G G +GE G GP G GPAG G PGP GPRG KGE G++G G Sbjct: 1059 -----------GKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKG 1107 Query: 1487 RR 1488 R Sbjct: 1108 HR 1109 Score = 457 bits (1176), Expect = e-128 Identities = 361/1003 (35%), Positives = 409/1003 (40%), Gaps = 188/1003 (18%) Query: 564 NLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQG-----PKG------QKGSVG 612 N +G GPKGD G PG G G PG PG PG G PGP G P G Q S Sbjct: 100 NGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYD 159 Query: 613 DPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGS 672 G G GP GP G GPPG+ G G+ G PG GPPG PG GP G G Sbjct: 160 VKSGVAVGGLAGYPGPAGPPGPPGPPGTS--GHPGSPGSPGYQGPPGEPGQAGPSGPPGP 217 Query: 673 PGPQGPPGPVGLQ------GLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGM 726 PG GP GP G G GE GLPG G KGP G PG G +G +G G GE G Sbjct: 218 PGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGE 277 Query: 727 RGLPGAVGE---PGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGP 783 G PG GE PG GA GP GP G G RG GL G G RG G G G+P GP Sbjct: 278 TGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQP---GP 334 Query: 784 QGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGP------PGA 837 GP G G PG PG KGE G G ++ PGP G GA GPPGP PG Sbjct: 335 PGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGG 394 Query: 838 PGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG----------PSIPGPPGPRGPPGE-GL 886 G GPAG+PG ++ +GPPGP G G PG G PGPRG GE G+ Sbjct: 395 KGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGI 454 Query: 887 PGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFG 946 PG PG G + + G PG G PG G++G PG RG G G+PG Sbjct: 455 PGVPGAKG---EDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGE--- 508 Query: 947 LNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGP-SEGGSSSTMYVSGPPGPPGP----- 1000 +G PGP GP+G G+ G GVPG G+ P S GG S G PGPPG Sbjct: 509 ---RGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGS----DGKPGPPGSQGESG 561 Query: 1001 -PGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSE 1059 PGPPG GQ +D +G +G PG PGP GP GET Sbjct: 562 RPGPPGPSGPRGQPGVMGFPGPKGNDGAPG-KNGERGGPGGPGPQGPPGK-NGET----- 614 Query: 1060 LASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGD 1119 GP+GPPGP G GD Sbjct: 615 ----------------------------------------------GPQGPPGPTGPGGD 628 Query: 1120 GSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGP 1179 D + L + +G G PG G PG PG + G +G G Sbjct: 629 KG----DTGPPGPQGLQGLPGTG---GPPGENGKPGEPGPKGDAGAPGAPGG--KGDAGA 679 Query: 1180 PGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYA 1239 PG GPPG+ G GL GPPGP G G GPPG GA T Sbjct: 680 PGERGPPGLAG----------------APGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPG 723 Query: 1240 AENSDSFRSELIS----------------YLTSPDVRSFIVGPPGPPGPQGPPGDSRLLS 1283 + R L S + D GP GPPGP G PGD Sbjct: 724 LQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGG 783 Query: 1284 TDA----SHSRGSSSSSHSSSVRRGSSYSSSMSTGG--GGAGSLGAGGAFGEAA--GDRG 1335 + RGS + + + + G GG G GA G GE G G Sbjct: 784 APGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAG 843 Query: 1336 PYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAY 1395 P G GP G G G GG A F G + + G Sbjct: 844 PPGGS-GPAGPPGPQGVKGERGSPGGPGAAGFPG-----------ARGLPGPPGSNGNP- 890 Query: 1396 TVQGPPGQPGPQGPPGISKVFSAYSN--VTADLMDFFQ-----TYGAIQGPPGQKGEMGT 1448 GP G PG GPPG + A + V+ D Q + GA QGPPG G +G Sbjct: 891 GPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGA-QGPPGAPGPLGI 949 Query: 1449 PGPKGDRGPAGPPGHPGP---PGPRGHKGEKGDKGDQVYAGRR 1488 G G RG AGPPG PGP PGP+G KGE G G +G R Sbjct: 950 AGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGER 992 Score = 453 bits (1165), Expect = e-127 Identities = 346/957 (36%), Positives = 395/957 (41%), Gaps = 244/957 (25%) Query: 560 QENGNLRGSPGPKGDMGSPGPKGD---RGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGM 616 Q + +G PGP G GSPG KG+ G PG PG+ G G PGP G G G G G Sbjct: 374 QGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGE 433 Query: 617 EGPMGQRGREGPMGPRGEAGPPG----------------------SGEKGERGAAGEPGP 654 G G +G GP G RGEAG PG G GERGA G GP Sbjct: 434 PGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGP 493 Query: 655 HGPPGVPGSVGPKGSSGSPGPQGP------PGPVGLQGLRGEVGLPGVKGDKGPMGPPGP 708 GP G+PG GP G G+PGP GP PG G+ G G G+PG G G G PGP Sbjct: 494 AGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGP 553 Query: 709 KGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKG----------AMGPAGPDGHQGPRGEQG 758 G QGE G G G G RG PG +G PG KG GP GP G QGP G+ G Sbjct: 554 PGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGP-GPQGPPGKNG 612 Query: 759 LTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGT---------PGRPGIKGEPGAPGKIV 809 TG G GP GP GD G G GPQG QGLPGT PG PG KG+ GAPG Sbjct: 613 ETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPG--- 669 Query: 810 TSEGSSMLTVPGPPGPP---------------------GAMGPPGPPGAPGPAGPAGLPG 848 G PG GPP GA GPPGPPGA G G G+PG Sbjct: 670 APGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPG 729 Query: 849 HQEVLNLQGP---------------PGPPGPRGPPGPSIPGPPGPRGPPGE-------GL 886 + L GP PG GPRGP GP GPPGP G PG+ GL Sbjct: 730 ERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPI--GPPGPAGQPGDKGEGGAPGL 787 Query: 887 PGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFG 946 PG GP GS ET GPPGP G PG G G PG +G +G G G + Sbjct: 788 PGIAGPRGSPGERGET---GPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGP 844 Query: 947 LNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSG---PSEGGSSSTMYVSGPPGPPGPPGP 1003 GP GPPGPQG KG++G PG PGA G P P GS+ GP G PG GP Sbjct: 845 PGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGP 904 Query: 1004 PGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGP--VTTITGETFDYSELA 1061 PG ++G +S + D+ + G G GPPG PGP + ITG Sbjct: 905 PGPAGNTGAPGSPGVSG-PKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITG--------- 954 Query: 1062 SHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGS 1121 + L GP G PGP G+ G Sbjct: 955 ---------------------------------------ARGLAGPPGMPGPRGSPGPQG 975 Query: 1122 LLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPG 1181 + ++G+S G GPPGP GLPG L G+ G G G Sbjct: 976 VKGES---------GKPGANGLS-GERGPPGPQGLPG---------LAGT--AGEPGRDG 1014 Query: 1182 PPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAE 1241 PG G+PG S D G PG PG PGPPGP GP G SG Sbjct: 1015 NPGSDGLPGRDGSPGGKGDRGE----NGSPGAPGAPGHPGPPGPVGPAGKSGD------- 1063 Query: 1242 NSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSV 1301 R E S P G G PGPQGP GD +G + ++ + Sbjct: 1064 -----RGE--SGPAGPAGAPGPAGSRGAPGPQGPRGD-----------KGETGERGAAGI 1105 Query: 1302 RRGSSYSSSMSTGG--GGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYA-- 1357 + + + G G AG GA G+ G AG RGP G GP G G + G Sbjct: 1106 KGHRGFPGNPGAPGSPGPAGQQGAIGSPG-PAGPRGPVGPS-GPPGKDGTSGHPGPIGPP 1163 Query: 1358 ---GNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPG 1411 GN G G++ + G PGQPGP GPPG Sbjct: 1164 GPRGNRGERGSEGS-----------------------------PGHPGQPGPPGPPG 1191 Score = 445 bits (1144), Expect = e-124 Identities = 322/823 (39%), Positives = 360/823 (43%), Gaps = 157/823 (19%) Query: 566 RGSPGPKGDMGS---------PGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGM 616 RG+PGP G G+ PG G RG PG+PG PG G PGP G +G+ G G PG Sbjct: 509 RGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGP 568 Query: 617 EGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGP- 675 GP GQ G G GP+G G PG + GERG G PGP GPPG G GP+G G GP Sbjct: 569 SGPRGQPGVMGFPGPKGNDGAPG--KNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPG 626 Query: 676 -----QGPPGPVGLQGL---------RGEVGLPGVKGDKGPMGPPGPKGDQG---EKGPR 718 GPPGP GLQGL G+ G PG KGD G G PG KGD G E+GP Sbjct: 627 GDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPP 686 Query: 719 GLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGD---- 774 GL G PG+RG G G G KGA GP GP G G G QG+ G G G PGP GD Sbjct: 687 GLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEP 746 Query: 775 --------PGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGK--IVTSEGS-SMLTVPGPP 823 PGK G GP GP G PG G+PG KGE GAPG I GS GPP Sbjct: 747 GGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPP 806 Query: 824 GPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIP-GPPGPRGPP 882 GP G G PG G PG G G PG + G GPPG GPPG S P GPPGP+G Sbjct: 807 GPAGFPGAPGQNGEPGGKGERGAPGEK------GEGGPPGVAGPPGGSGPAGPPGPQGVK 860 Query: 883 GE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSG 941 GE G PG PG G G G PGPPG G+ GPPGP G G+ G PG +G Sbjct: 861 GERGSPGGPGAAG---------FPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPG--PAG 909 Query: 942 SSSFGLNLQGPPGPPGPQGPKGDKGDPGV---PGALGIPSGPSEGGSSSTMYVSGPPGPP 998 ++ G PG PG GPKGD G PG PGA G P P G + G GPP Sbjct: 910 NT-------GAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPP 962 Query: 999 GPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYS 1058 G PGP GS G + + + LSG +GPPGP G PG T GE Sbjct: 963 GMPGPRGSPGPQGVKGES-------GKPGANGLSGERGPPGPQGLPGLAGT-AGEPGRDG 1014 Query: 1059 ELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASG 1118 S + S G + D + G G PGPPG G Sbjct: 1015 NPGSDGLPGRDGSPGG------------------KGDRGENGSPGAPGAPGHPGPPGPVG 1056 Query: 1119 DGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSE-FRGIV 1177 S D E + S G PGP GP G G + E + ++G F G Sbjct: 1057 PAGK-SGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNP 1115 Query: 1178 GPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALAT 1237 G PG PGP G G + S PGP GP GP GP GPPG G Sbjct: 1116 GAPGSPGPAGQQGAIGS-------------------PGPAGPRGPVGPSGPPGKDGT--- 1153 Query: 1238 YAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSH 1297 S GP GPPGP+G G+ RGS S Sbjct: 1154 -----------------------SGHPGPIGPPGPRGNRGE-----------RGSEGSPG 1179 Query: 1298 SSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTD 1340 + GG G+ G GE AG PY D Sbjct: 1180 HPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYGD 1222 Score = 366 bits (939), Expect = e-100 Identities = 226/508 (44%), Positives = 249/508 (49%), Gaps = 105/508 (20%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTP---GIP---------GPLGHPGPQGPKGQKGSVG 612 L+G PG +G +GSPGPKGD+G PG P G+P GP+G PGP G G KG G Sbjct: 724 LQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGG 783 Query: 613 DPGM------EGPMGQRGREGPMGPRGEAGPPGS----GEKGERGAAGEPGPHGPPGVPG 662 PG+ G G+RG GP GP G G PG G KGERGA GE G GPPGV G Sbjct: 784 APGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAG 843 Query: 663 SVGPKGSSGSPGPQ------GPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKG 716 G G +G PGPQ G PG G G G GLPG G G GPPGP G G+ G Sbjct: 844 PPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDG 903 Query: 717 P------RGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLT---------G 761 P G G PG+ G G G+PG KG+ G GP G GP G G+T G Sbjct: 904 PPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPG 963 Query: 762 MPGIRGPPGP---SGDPGKPGLT------GPQGPQGLP------GTPGRPGIKGEPGAPG 806 MPG RG PGP G+ GKPG GP GPQGLP G PGR G G G PG Sbjct: 964 MPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPG 1023 Query: 807 KIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRG 866 + + G G PG PGA G PGPPG GPAG +G G G PGP G RG Sbjct: 1024 RDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRG 1083 Query: 867 PPGPSIPGPPGPRGPPGE----------GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGP 916 PGP GP G +G GE G PG PG PGS PGP G G Sbjct: 1084 APGPQ--GPRGDKGETGERGAAGIKGHRGFPGNPGAPGS------------PGPAGQQGA 1129 Query: 917 KGDQGPPGPRGHQGEQGLPG-FSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALG 975 G GP GPRG G G PG TSG GP GPPGP+G +G++G G PG G Sbjct: 1130 IGSPGPAGPRGPVGPSGPPGKDGTSGH-------PGPIGPPGPRGNRGERGSEGSPGHPG 1182 Query: 976 IPSGPSEGGSSSTMYVSGPPGPPGPPGP 1003 P GPPGPPG PGP Sbjct: 1183 QP---------------GPPGPPGAPGP 1195 Score = 233 bits (594), Expect = 1e-60 Identities = 241/789 (30%), Positives = 285/789 (36%), Gaps = 225/789 (28%) Query: 823 PGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG-PSIPGPPGPRGP 881 P PP A P PP GP GP G PG PPG PG G PG P PG PG GP Sbjct: 89 PQPPTA--PTRPPNGQGPQGPKGDPG---------PPGIPGRNGDPGIPGQPGSPGSPGP 137 Query: 882 PG------------------------------------EGLPGPPGPPGSF---LSNSET 902 PG G PGPPGPPG+ S Sbjct: 138 PGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSP 197 Query: 903 FLSGPP------GPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPP 956 GPP GP GPPGP G GP GP G GE G PG ++GP G P Sbjct: 198 GYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIP 257 Query: 957 GPQGPK---------GDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSI 1007 G G K G+KG+ G PG G P E G+ M G PG G PG PG+ Sbjct: 258 GFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAA 317 Query: 1008 SSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSY 1067 + G +D R G G PGPPGPPG F S A V Sbjct: 318 GARG------------NDGAR----GSDGQPGPPGPPGTA------GFPGSPGAKGEVGP 355 Query: 1068 LRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDY 1127 + G A QR + Q G +GPPGPPG +G Sbjct: 356 AGSPGSNG-------------APGQRGEPGP---QGHAGAQGPPGPPGING--------- 390 Query: 1128 AELSSRILSYMSSSGIS-----IGLPGPPGP------PGLPGTSYEELLSLLRGSE---- 1172 S M +GI +G GPPGP PGL G + E + +G Sbjct: 391 ---SPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRG 447 Query: 1173 FRGIVGPPGPP---------GPPGIPG--NVWSSISVEDLSSYLHTAGLSFIPGPPGP-- 1219 RG G PG P G PG PG + + + AG + IPG GP Sbjct: 448 ERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAG 507 Query: 1220 ----PGPPGPRGP------------PGVSGALATYAAENSDSFRSELISYLTSPDVRSFI 1263 PGP GPRG PG+ G + SD P Sbjct: 508 ERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDG--------KPGPPGSQGE 559 Query: 1264 VGPPGPPGPQGPPGDSRLL------STDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGG 1317 G PGPPGP GP G ++ D + + +G + + G Sbjct: 560 SGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGP 619 Query: 1318 AGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYA-----GNGGLLGADFAGDLD 1372 G G GG G+ G GP G PG G G E G G+ G GA G D Sbjct: 620 PGPTGPGGDKGD-TGPPGPQGLQGLPGTG-GPPGENGKPGEPGPKGDAGAPGAP-GGKGD 676 Query: 1373 YNELAVRVSESMQRQGLLQGMAYTVQGPP------GQPGPQGPPGISKVFSAYSNVTADL 1426 R + L+G A GPP G GP GPPG + Sbjct: 677 AGAPGERGPPGLAGAPGLRGGA----GPPGPEGGKGAAGPPGPPGAAGT----------- 721 Query: 1427 MDFFQTYGAIQGPPGQKGEMGTPGPKGDR---------------GPAGPPGHPGPPGPRG 1471 +QG PG++G +G+PGPKGD+ GP GP G GPPGP G Sbjct: 722 -------PGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAG 774 Query: 1472 HKGEKGDKG 1480 G+KG+ G Sbjct: 775 QPGDKGEGG 783 Score = 66.6 bits (161), Expect = 2e-10 Identities = 52/168 (30%), Positives = 63/168 (37%), Gaps = 30/168 (17%) Query: 1332 GDRGPYGTDIGPGGGYGAAAEGGMYAGNG--GLLGADFAGDLDYNELAVRVSESMQRQGL 1389 GD GP G G G G + G G G+ + G +Y+ + + G+ Sbjct: 109 GDPGPPGIP-GRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSP---QYDSYDVKSGV 164 Query: 1390 LQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTP 1449 G GP G PGP GPPG S G PG G G Sbjct: 165 AVGGLAGYPGPAGPPGPPGPPGTS------------------------GHPGSPGSPGYQ 200 Query: 1450 GPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 GP G+ G AGP G PGPPG G G G G+ GR R + P Sbjct: 201 GPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPP 248 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 494 bits (1273), Expect = e-139 Identities = 353/969 (36%), Positives = 425/969 (43%), Gaps = 200/969 (20%) Query: 565 LRGSPGPKGDMGSP----------GPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDP 614 L+G G KGD G GP G G PG PG PG LG PG +G KGQ G+ G Sbjct: 467 LQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPK 526 Query: 615 GMEGPMGQRGREGPMGPRGEAGP--PGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGS 672 G+ G G G G G +GE G G KG++G G PG G PG+PG+ G G G Sbjct: 527 GLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGL 586 Query: 673 PGPQGPPGPVGLQGLRG---EVGLPGVKGDKGPMGPPG--PKGDQGEKGPRGLTGEPGMR 727 PGP+G PG + +G RG GLPG+ G+ GPMGPPG P G GEKG +G+ G PG Sbjct: 587 PGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQP 646 Query: 728 GLPGAVGEPGAK-------GAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPG- 779 G+PG G+PG G G G DG G G+ GL G PG+ G PG G+PG PG Sbjct: 647 GIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI 706 Query: 780 -LTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPG-- 836 L GP GP+G PG PG PG G PG G + GPPGPPG GP G PG Sbjct: 707 GLPGPPGPKGFPGIPGPPGAPGTPGRIG------------LEGPPGPPGFPGPKGEPGFA 754 Query: 837 APGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS-IPGPPGPRGPPG-EGLPGPPGPPG 894 PGP GP GLPG + L +G G PGP GPPG + + G PGP+G G G PGP GPPG Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814 Query: 895 SFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPG 954 + GPPGPPG PGP G G G G +G+ G PG G +G PG Sbjct: 815 L----PGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGE----RGSPG 866 Query: 955 PPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEI 1014 PG GP G G PG+PG G P G+ M + GPPGPPGP G PG G + Sbjct: 867 IPGAPGPIGPPGSPGLPGKAGASGFP---GTKGEMGMMGPPGPPGPLGIPGRSGVPGLKG 923 Query: 1015 QQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPV-TTITGETFDYSELASHVVSYLRTSGY 1073 + G +G PG PGPPGP+ + G + E + Sbjct: 924 DDGLQGQPGLPGPTGE-KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI-------- 974 Query: 1074 GVSLFSSSISSEDILAVLQRDDVRQYL--RQYLMGPRGPPGPPGASGDGSLLSLDYAELS 1131 +S L D + L + L GP GP G PG G L+ + + Sbjct: 975 ------PGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT 1028 Query: 1132 SRILSYMSSSGIS-----IGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPP 1186 + + G+ G+PG PG PGLPG ++ + G+ GP G PG P Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1088 Query: 1187 GIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSF 1246 G PGN SV D PG PG PG PG +G PG+ G T Sbjct: 1089 GYPGNPGIKGSVGD-------------PGLPGLPGTPGAKGQPGLPGFPGT--------- 1126 Query: 1247 RSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSS 1306 GPPGP G GPPG+ L Sbjct: 1127 -----------------PGPPGPKGISGPPGNPGL------------------------- 1144 Query: 1307 YSSSMSTGGGGAGSLGAGGAFGEAA--GDRGPYGTD--IGPGGGYGAAAEGGMYAGNGGL 1362 G G +G GG G+ G++G G D GP G G + G GN G Sbjct: 1145 --------PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF--GNPGP 1194 Query: 1363 LGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNV 1422 G + + G L G + G PG PGP+G PG Sbjct: 1195 PG-------------LPGLSGQKGDGGLPG----IPGNPGLPGPKGEPG----------- 1226 Query: 1423 TADLMDFFQTYGAIQGPPGQKGEMG--TPGPKGDRGPAGPPGHPGPPGPRGH-------- 1472 F + +QGPPG G G GPKG+ GP GPPG PG PGP G Sbjct: 1227 -------FHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGG 1279 Query: 1473 -KGEKGDKG 1480 KGEKG+ G Sbjct: 1280 IKGEKGNPG 1288 Score = 481 bits (1237), Expect = e-135 Identities = 366/1017 (35%), Positives = 439/1017 (43%), Gaps = 183/1017 (17%) Query: 568 SPGPKGDM-GSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGRE 626 SPG K D G G KG+RGFPG G PG G PGP+GP G +G GD G+ GP G +G Sbjct: 33 SPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIR 92 Query: 627 GPMGPRGEAGPPG-------------------SGEKGERGAAGEP------GPHGPPGVP 661 GP G G G PG +G KGERG G P GP GPPG+P Sbjct: 93 GPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP 152 Query: 662 GS------------VGPKGSSGSPGP---QGPPGPVGLQGLRGEVGLPGVKGDKGPMGPP 706 G GPKG+ G PGP QG PGP G+ G G G PG+ G GP G P Sbjct: 153 GMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLP 212 Query: 707 GPKGD--------QGEKGPRGLTGEPGM-------------------RGLPGAVGEPGAK 739 GPKG+ +GEKG +GL G PG +GLPG G PG Sbjct: 213 GPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPP 272 Query: 740 GAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIK 799 G GP GP G G +GE+G G PG RG PG G+ G+PG+ G G G PG PGR G K Sbjct: 273 GIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEK 330 Query: 800 GE------PGAPGKIVTSEGSSM-LTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEV 852 G+ PG PG ++ G+ + + G G PG G G G PG GP GLPG Sbjct: 331 GQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGA 390 Query: 853 LNLQGPPGPP---------GPRGPPGPSIPGPPGPRGPPG-EGLPGPPGPPGSFLSNSET 902 + GPPGPP G GPPG SIPGPPG G PG GLPGPPGP G + S+ Sbjct: 391 A-VMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449 Query: 903 FLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPK 962 PGPPGPPG GD+G G +G +G++G F + G + GPPG PG G Sbjct: 450 ICE--PGPPGPPGSPGDKGLQGEQGVKGDKGDTCF-----NCIGTGISGPPGQPGLPGL- 501 Query: 963 GDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYM 1022 PG PG+LG P E G + G PG PG PG PG S G+ M Sbjct: 502 -----PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGM 556 Query: 1023 QSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLR--TSGYGVSLFSS 1080 + D G G PG PG PG + G E R G+ Sbjct: 557 KGDKGELGSPGAPGLPGLPGTPGQ-DGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG 615 Query: 1081 SISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGD-GSLLSLDYAELSSRILSYMS 1139 +I V + Q + G G PG PG GD G ++ Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675 Query: 1140 SSGI--SIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSIS 1197 G+ GLPG PG PG+PG+ E G G+ GPPGP G PGIPG + + Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEP------GIPGIGLPGPPGPKGFPGIPGPPGAPGT 729 Query: 1198 VEDLSSYLHTAGLSFIPGPPGPPGP--------PGPRGPPGVSGALATYAAENSDSFRSE 1249 + GL PGPPG PGP PGP GPPG+ G + F Sbjct: 730 PGRI-------GLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGP 782 Query: 1250 LISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSS 1309 P R+ + G PGP G GP G + G + Sbjct: 783 -----PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI-------- 829 Query: 1310 SMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDI-GPGGGYGAAAEGGMYAGNGGLLGADFA 1368 G G G G GE GD GP G D+ GP G G+ G G +G + Sbjct: 830 -----PGPIGQPGLHGIPGE-KGDPGPPGLDVPGPPGERGSPG----IPGAPGPIGPPGS 879 Query: 1369 GDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMD 1428 L A + G++ GPPG PGP G PG S V Sbjct: 880 PGLPGKAGASGFPGTKGEMGMM--------GPPGPPGPLGIPGRSGV------------- 918 Query: 1429 FFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPR-----GHKGEKGDKG 1480 ++G G +G+ G PGP G++G G PG PGPPGP G KGEKG+ G Sbjct: 919 -----PGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG 970 Score = 465 bits (1197), Expect = e-130 Identities = 325/855 (38%), Positives = 389/855 (45%), Gaps = 183/855 (21%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPG---------------PLGHPGPQGPKGQ---- 607 G PG G G+ GPKGDRGFPG PG PG P G PGP GP G Sbjct: 760 GPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIG 819 Query: 608 -KGSVGDPGMEGPMGQRGREGPMGPRGEAGPPG------SGEKGERGAAGEPGPHGPPGV 660 +G G PG+ GP+GQ G G G +G+ GPPG GE+G G G PGP GPPG Sbjct: 820 VQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGS 879 Query: 661 PGSVGPKGSSGSPG---------PQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGD 711 PG G G+SG PG P GPPGP+G+ G G GL G G +G G PGP G+ Sbjct: 880 PGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE 939 Query: 712 QGEKGPRGLTGEPG-----MRGLPGAVGEPGAKGAMGPAGPDGHQ---GPRGEQGLTGMP 763 +G KG GL G PG + G G GEPG G G +GP G+Q G G+ GL+G P Sbjct: 940 KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQP 999 Query: 764 GIRGPPGPSGD---PGKPGLTGP------------QGPQGLPGTPGRPGIKGEPGAPG-- 806 G+ GPPGP G+ PG+PGL GP GPQG+ G PG G+ G+PG+PG Sbjct: 1000 GLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLP 1059 Query: 807 ---KIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPG 863 G S + +PG PGP G G PG PG PG G G PG L G PG PG Sbjct: 1060 GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPG------LPGLPGTPG 1113 Query: 864 PRGPPG----PSIPGPPGPR---GPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPG 915 +G PG P PGPPGP+ GPPG GLPG PGP G G PG PGPPG Sbjct: 1114 AKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGG---------GGHPGQPGPPG 1164 Query: 916 PK---GDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPG 972 K G G PGP G +GE G PGF GPPG PG G KGD G PG+PG Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGN----------PGPPGLPGLSGQKGDGGLPGIPG 1214 Query: 973 ALGIPSGPSEGGSSSTMYVSGPPGPPGPPGP--PGSISSSGQEIQQYISEYMQSDSIRSY 1030 G+P E G V GPPGPPG PGP G + G Q R Sbjct: 1215 NPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP----------QGPPGRPG 1264 Query: 1031 LSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAV 1090 L G +GPPG PG G I GE + + + L+ L + Sbjct: 1265 LPGPEGPPGLPGNGG----IKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNP--------- 1311 Query: 1091 LQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGP 1150 R L G +G PG PG G + S + G GL GP Sbjct: 1312 ---------GRPGLNGMKGDPGLPGVPGFPGMKG------PSGVPGSAGPEG-EPGLIGP 1355 Query: 1151 PGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGL 1210 PGPPGLPG S + ++ +G GPPG PG PG+ G Sbjct: 1356 PGPPGLPGPSGQSII-------IKGDAGPPGIPGQPGLKG-------------------- 1388 Query: 1211 SFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPP 1270 +PGP GP G PGP GPPG G + + + + P R + GPPGP Sbjct: 1389 --LPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGD-PGLPGQPGTRG-LDGPPGPD 1444 Query: 1271 GPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEA 1330 G QGPPG G+SS +H + R S + + G + G + Sbjct: 1445 GLQGPPGPP-----------GTSSVAHGFLITRHSQTTDAPQCPQGTL-QVYEGFSLLYV 1492 Query: 1331 AGDRGPYGTDIGPGG 1345 G++ +G D+G G Sbjct: 1493 QGNKRAHGQDLGTAG 1507 Score = 462 bits (1190), Expect = e-130 Identities = 369/1013 (36%), Positives = 421/1013 (41%), Gaps = 193/1013 (19%) Query: 561 ENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPM 620 E G++ PG KGD G G G G PG PG PG G PG GPKG+ G + G GP Sbjct: 546 EPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPP 605 Query: 621 GQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGS-------- 672 G G G G G GPPG G G G G G G PG PG GPKG G Sbjct: 606 GNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKP 665 Query: 673 --PGPQGPPGPVGL---QGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMR 727 PG G G VGL GL G+ GLPG+ G KG G PG G GP G G PG+ Sbjct: 666 GLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPG----IGLPGPPGPKGFPGIP 721 Query: 728 GLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQ 787 G PGA G PG G GP GP G GP+GE G + GPPGP G PG G GP+G + Sbjct: 722 GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF----ALPGPPGPPGLPGFKGALGPKGDR 777 Query: 788 GLPGTPGRPGIKGEPGAPGK--IVTSEGSSMLTVPGPPGPP-----GAMGPPGPPGAPGP 840 G PG PG PG G G PG V G PGP GPP G GPPGPPG PGP Sbjct: 778 GFPGPPGPPGRTGLDGLPGPKGDVGPNGQ-----PGPMGPPGLPGIGVQGPPGPPGIPGP 832 Query: 841 AGPAGLPGHQEVLNLQGP-----PGPPGPRGPPGPSIPGPPGPRGPPGE-GLPGPPGPPG 894 G GL G GP PGPPG RG PG IPG PGP GPPG GLPG G G Sbjct: 833 IGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPG--IPGAPGPIGPPGSPGLPGKAGASG 890 Query: 895 SFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPG 954 + E + GPPGPPGP G G G PG +G G QG PG G PG Sbjct: 891 FPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950 Query: 955 PPGPQGP-----KGDKGDPGVPGA---------LGIPSGPSEGGSSSTMYVSGPPGP--- 997 PPGP P KG+KG+PG+PG G+P P + G S + GPPGP Sbjct: 951 PPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN 1010 Query: 998 PGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTT--ITGETF 1055 PG PG PG I G ++ I + GV+GPPGP G PG + + G+ Sbjct: 1011 PGLPGQPGLIGPPG--LKGTIGDMGFPGP-----QGVEGPPGPSGVPGQPGSPGLPGQKG 1063 Query: 1056 DYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPG 1115 D + +S + G L GP+G PG PG Sbjct: 1064 DKGDPG---ISSIGLPG-------------------------------LPGPKGEPGLPG 1089 Query: 1116 ASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEF-- 1173 G+ + S+G PG PG PG PG + L G+ Sbjct: 1090 YPGNPGIKG-------------------SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPP 1130 Query: 1174 --RGIVGPPGPPGPPGIPGNVWSS--ISVEDLSSYLHTAGLSFIPGP------PGPP--G 1221 +GI GPPG PG PG PG V G IPGP PG P G Sbjct: 1131 GPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFG 1190 Query: 1222 PPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSF--IVGPPGP---------- 1269 PGP G PG+SG L P F + GPPGP Sbjct: 1191 NPGPPGLPGLSGQKGDGGLPGIPG-NPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEG 1249 Query: 1270 ----PGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGG 1325 PGPQGPPG L + G + + G G G G Sbjct: 1250 PKGNPGPQGPPGRPGLPGPEGP---------------PGLPGNGGIKGEKGNPGQPGLPG 1294 Query: 1326 AFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGA-DFAGDLDYNELAVRVSESM 1384 G GD+GP G G G GM G+ GL G F G M Sbjct: 1295 LPG-LKGDQGPPGLQ----GNPGRPGLNGM-KGDPGLPGVPGFPG--------------M 1334 Query: 1385 QRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKG 1444 + + G A +G PG GP GPPG+ + D I G PG KG Sbjct: 1335 KGPSGVPGSA-GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGP-----PGIPGQPGLKG 1388 Query: 1445 EMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 G GP+G GP GPPG PG G G G G KGD G+ R + P Sbjct: 1389 LPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPP 1441 Score = 433 bits (1113), Expect = e-121 Identities = 294/711 (41%), Positives = 342/711 (48%), Gaps = 122/711 (17%) Query: 559 EQENGNLRGSPGPKGDMGS---PGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPG 615 E+ + + G+PGP G GS PG G GFPGT G G +G PGP GP G G G PG Sbjct: 861 ERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPG 920 Query: 616 MEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGP--PGVPGSVGPKGSSGSP 673 ++G G +G+ G GP +GEKG +G G PGP GP P + GS G KG G P Sbjct: 921 LKGDDGLQGQPGLPGP--------TGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLP 972 Query: 674 GPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAV 733 G G GP G QGL G+ G PG+ G G GPPGPKG+ G G GL G PG++G G + Sbjct: 973 GIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDM 1032 Query: 734 GEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTP 793 G PG +G GP GP G G G GL G G +G PG S G PGL GP+G GLPG P Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGIS-SIGLPGLPGPKGEPGLPGYP 1091 Query: 794 GRPGIK---GEPGAPGKIVT--SEGSSMLT----VPGPPGPPGAMGPPGPPGAPGPAGPA 844 G PGIK G+PG PG T ++G L PGPPGP G GPPG PG PG GP Sbjct: 1092 GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPV 1151 Query: 845 GLPGHQEVLNLQGPPGPPGPRGPPG-PSIPGPPGPRGPPGE---GLPGPPGPPGSFLSNS 900 G GH G PGPPG +G PG IPGP G +G PG+ G PGPPG PG Sbjct: 1152 GGGGH------PGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKG 1205 Query: 901 ETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQG 960 + L G PG PG PGPKG+ G G G QG G PG S G L+GP G PGPQG Sbjct: 1206 DGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG-------SPGPALEGPKGNPGPQG 1258 Query: 961 PKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISE 1020 P G PG+PG G P P GG G PG PG PG PG G Sbjct: 1259 P---PGRPGLPGPEGPPGLPGNGGIKGE---KGNPGQPGLPGLPGLKGDQG-------PP 1305 Query: 1021 YMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSS 1080 +Q + R L+G++G PG PG PG F + S V G Sbjct: 1306 GLQGNPGRPGLNGMKGDPGLPGVPG---------FPGMKGPSGVPGSAGPEG-------- 1348 Query: 1081 SISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSS 1140 L+GP GPPG PG SG ++ D Sbjct: 1349 --------------------EPGLIGPPGPPGLPGPSGQSIIIKGDAGP-----PGIPGQ 1383 Query: 1141 SGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVED 1200 G+ GLPGP GP GLPG + GPPG PG G+PG + D Sbjct: 1384 PGLK-GLPGPQGPQGLPGPT-----------------GPPGDPGRNGLPGFDGAGGRKGD 1425 Query: 1201 --LSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVS----GALATYAAENSDS 1245 L T GL GPPGP G GP GPPG S G L T ++ +D+ Sbjct: 1426 PGLPGQPGTRGLD---GPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDA 1473 Score = 253 bits (645), Expect = 1e-66 Identities = 243/720 (33%), Positives = 273/720 (37%), Gaps = 184/720 (25%) Query: 827 GAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS-IPGPPGP---RGPP 882 G G G G PG G GLPG GP GPPGPRG G IPGPPGP RGPP Sbjct: 42 GIKGEKGERGFPGLEGHPGLPG------FPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPP 95 Query: 883 GEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGS 942 G LPG PG PG L G PG G PGP+G G G +G +G G PGF Sbjct: 96 G--LPGFPGTPG---------LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP---- 140 Query: 943 SSFGLNLQGPPGPPGPQGPKGD------------KGDPGVPGALGIPSGPSEGGSSSTMY 990 LQGPPGPPG G KG+ KG+PG PG GI P G + Sbjct: 141 -----GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIG 195 Query: 991 VSGPPG---PPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPV 1047 GPPG PPGPPG PG + G Q E G QG GPPGPPG + Sbjct: 196 PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGE-----------KGEQGLQGPPGPPGQI 244 Query: 1048 TTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGP 1107 S I Q+ D Q L G Sbjct: 245 ---------------------------------SEQKRPIDVEFQKGD------QGLPGD 265 Query: 1108 RGPPGPPGASGDGSLLSLDYAELSSR----------ILSYMSSSGISIGLPGPPGPPGLP 1157 RGPPGPPG G + E + GI GLPG PG PG P Sbjct: 266 RGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP-GLPGDPGYPGEP 324 Query: 1158 GTSYEELLSLLRGSEFRGIVGPPGPPGPPGI----PG-----NVWSSISVEDLSSYLHTA 1208 G E +G G GPPGPPG+ PG +I + L Sbjct: 325 GRDGE-----------KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGER 373 Query: 1209 GLSFIPGPPGPPGPP-----GPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFI 1263 G I GPPG PGPP GP GPPG G E L + Sbjct: 374 GFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGL 433 Query: 1264 VGP----------------PGPPGPQGPPGDSRLLSTD-ASHSRGSSSSSHSSSVRRGSS 1306 GP PGPPGP G PGD L +G + + + G Sbjct: 434 PGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPP 493 Query: 1307 YSSSMSTGGGGAGSLGAGGAFGE--AAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLG 1364 + G GSLG G GE AG GP G G G GA G G +L Sbjct: 494 GQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP-GIPGAPGAPGFPGSKGEPGDIL- 551 Query: 1365 ADFAG-DLDYNELAVRVSESMQRQGLLQGMAYT--VQGPPGQPGPQGPPGISKVFSAYSN 1421 F G D EL + L G+ T G PG PGP+G PG Sbjct: 552 -TFPGMKGDKGELGSPGAPG------LPGLPGTPGQDGLPGLPGPKGEPG---------- 594 Query: 1422 VTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGD 1481 T+ +GPPG G PG G+ GP GPPG GPPGP G KG +G G+ Sbjct: 595 --------GITFKGERGPPGNP---GLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGN 642 Score = 174 bits (442), Expect = 4e-43 Identities = 183/604 (30%), Positives = 212/604 (35%), Gaps = 194/604 (32%) Query: 912 GPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVP 971 G G KG++G PG GH G LPGF GP GPPGP+G KGD G PG P Sbjct: 42 GIKGEKGERGFPGLEGHPG---LPGFP------------GPEGPPGPRGQKGDDGIPGPP 86 Query: 972 GALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYL 1031 G GI GPPG PG PG PG G + Sbjct: 87 GPKGI---------------RGPPGLPGFPGTPGLPGMPGHD------------------ 113 Query: 1032 SGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVL 1091 G PGP G PG T F S G+ Sbjct: 114 ----GAPGPQGIPGCNGTKGERGFPGSP------------GF------------------ 139 Query: 1092 QRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPP 1151 L GP GPPG PG G E S I+S + + G PGPP Sbjct: 140 ----------PGLQGPPGPPGIPGMKG----------EPGSIIMSSLPGPKGNPGYPGPP 179 Query: 1152 GPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLS 1211 G GLPG + GI GP GPPGPPG+ G L GL+ Sbjct: 180 GIQGLPGPT--------------GIPGPIGPPGPPGLMGPP----GPPGLPGPKGNMGLN 221 Query: 1212 FIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPG 1271 F GP G G G +GPPG G + S+ R + + GPPGPPG Sbjct: 222 F-QGPKGEKGEQGLQGPPGPPGQI-------SEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273 Query: 1272 PQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAA 1331 +GPPG +RG + G G G G GE Sbjct: 274 IRGPPGPPG--------GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPG 325 Query: 1332 --GDRGPYGTDIGPGGGYGAAAEG---GMYAGNGGLLGADFAGDLDYNELAVRVSESMQR 1386 G++G G D GP G G G+ G G +G E R +Q Sbjct: 326 RDGEKGQKG-DTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLP----GEKGERGFPGIQG 380 Query: 1387 QGLLQGM-AYTVQGPPGQPG---------PQGPPGISKVFSAYSNVTADLMDFFQTYGAI 1436 L G V GPPG PG +GPPGIS I Sbjct: 381 PPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS----------------------I 418 Query: 1437 QGPPGQKGEMGTPGPKGDRGPAGP----------------PGHPGPPGPRGHKGEKGDKG 1480 GPPG G+ G PG G GPAGP PG PG G +G +G KGDKG Sbjct: 419 PGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKG 478 Query: 1481 DQVY 1484 D + Sbjct: 479 DTCF 482 Score = 59.7 bits (143), Expect = 2e-08 Identities = 37/91 (40%), Positives = 39/91 (42%), Gaps = 30/91 (32%) Query: 1399 GPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGE---MGTPGPKGDR 1455 G PG PGP+GPPG P GQKG+ G PGPKG R Sbjct: 60 GLPGFPGPEGPPG---------------------------PRGQKGDDGIPGPPGPKGIR 92 Query: 1456 GPAGPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 GP G PG PG PG G G G G Q G Sbjct: 93 GPPGLPGFPGTPGLPGMPGHDGAPGPQGIPG 123 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 493 bits (1269), Expect = e-139 Identities = 349/988 (35%), Positives = 419/988 (42%), Gaps = 211/988 (21%) Query: 559 EQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPG---PLGHPGPQGPKGQKGSVGDPG 615 +Q N +G PGP+G +G PG KG +G PG G+PG P GHPG +G G+KG++G PG Sbjct: 704 QQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPG 763 Query: 616 MEGPMGQ------------RGREGPMGPRGEAGPPG----SGEKGERGAAGEPGPHGPPG 659 +GP+G RG +G G +GE G PG G KG+RG G+ GP G G Sbjct: 764 PQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDG 823 Query: 660 VPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRG 719 G G G +G PGP G G G G+ G G PG +G KG G PG G GEKG RG Sbjct: 824 PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG 883 Query: 720 LTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPG 779 + G+PG RG G G G++GA GP G G +G G G G PG RGP GP G G PG Sbjct: 884 VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG 943 Query: 780 LTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPG 839 GP GP G G PG PG +GE G GK ++ GP G G +G G PG PG Sbjct: 944 PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 1003 Query: 840 PAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS-IPGPPGPRGPPG----------EGLPG 888 P G GLPG +G PGP G G GP+ + G PG RG PG EG G Sbjct: 1004 PPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1063 Query: 889 PPGPPGSFLSNSETFLSGP------PGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGS 942 PPGP GS +GP PGP GPPGP G++G PG +G QG G G Sbjct: 1064 PPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG------ 1117 Query: 943 SSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPG--- 999 +QGP G PGP GP G G+ G G +G P + GS +GPPGPPG Sbjct: 1118 ------VQGPVGLPGPAGPAGSPGEDGDKGEIG---EPGQKGSKGDKGENGPPGPPGLQG 1168 Query: 1000 PPGPPGSISSSGQ---EIQQYISEYMQSDSIRSYLSGVQGPPGP------PGPPGPVTTI 1050 P G PG G+ QQ + + R G GPPGP PGPPG Sbjct: 1169 PVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR----GFPGPPGPIGLQGLPGPPGE---- 1220 Query: 1051 TGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGP 1110 GE D +GP GP Sbjct: 1221 KGENGD------------------------------------------------VGPMGP 1232 Query: 1111 PGPPGASGDGSLLSLDYAELSSRILSYMSSSGIS-----IGLPGPPGPPGLPGTSYEELL 1165 PGPPG G D + + + G G PGPPG G+ G E Sbjct: 1233 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE--- 1289 Query: 1166 SLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGP 1225 RG +G GPPG GPPG G G PG PGPPG PGP Sbjct: 1290 ---RGE--KGEAGPPGAAGPPGAKGPPGDD-------GPKGNPGPVGFPGDPGPPGEPGP 1337 Query: 1226 RGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTD 1285 G GV G E+ D + P S GPPGPPG +GPPG + Sbjct: 1338 AGQDGVGGD----KGEDGDPGQP-------GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1386 Query: 1286 ASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGE-----AAGDRGPYGTD 1340 + + + G + G G G G GE AAG GP G Sbjct: 1387 GEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGP- 1445 Query: 1341 IGPGGGYGAAAEGGMYA--GNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQ 1398 +GP G G + G G+ GL+G + Sbjct: 1446 MGPPGLPGLKGDPGSKGEKGHPGLIG--------------------------------LI 1473 Query: 1399 GPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPA 1458 GPPG+ G +G G+ QG PG KG+ G PGP G GP Sbjct: 1474 GPPGEQGEKGDRGLP---------------------GTQGSPGAKGDGGIPGPAGPLGPP 1512 Query: 1459 GPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 GPPG PGP GP+G+KG G G + +G Sbjct: 1513 GPPGLPGPQGPKGNKGSTGPAGQKGDSG 1540 Score = 481 bits (1238), Expect = e-135 Identities = 377/1068 (35%), Positives = 440/1068 (41%), Gaps = 281/1068 (26%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPK-------GQKGSVGDP--- 614 + G PG +G G PG GDRG PG PG+PG G PGP G G GS G Sbjct: 464 IMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISA 523 Query: 615 -----------------GMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHG- 656 G GPMG GR GP+G GP SG KGE G G GP G Sbjct: 524 QEAQAQAILQQARIALRGPPGPMGLTGRPGPVG-----GPGSSGAKGESGDPGPQGPRGV 578 Query: 657 --PPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKG------PMGPPGP 708 PPG G G +G G+ G +G PG G +G RG GLPG+ GDKG P GPPGP Sbjct: 579 QGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGP 638 Query: 709 KGDQG------EKGPRGLTGEPGMRGL------PGAVGEPGAKGAMGPAGPDGHQGPRGE 756 GD G E GPRGL GE G RGL PGA G+PG G GP GP G+ GP+GE Sbjct: 639 PGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE 698 Query: 757 QGLTGMPGIRGPPGPSGDPGKPGLTGP---QGPQGLPGTPGRPGIKGEPGAPGKIVTSEG 813 G PG +G PGP G PG G GP +GPQG PG G PG G PG PGK S Sbjct: 699 ---PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGE 755 Query: 814 SSMLTVPGPPGPPGAMGPPGPPGA------------------PGPAGPAGLPGHQEVLNL 855 L PGP GP G GP G GA PG G GL G + + Sbjct: 756 KGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 815 Query: 856 QGPPGPPGPRGPPGPSIP-GPPGPRGPPGE----GLPGPPGPPGSFLSNSETFLSGPPGP 910 GP G GP GP G + P G PGP G GE G+PG PG PG T G PG Sbjct: 816 IGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 875 Query: 911 ---------PGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGP 961 G PGP+G +GP GPRG +G +G G +S G GPPG GPQGP Sbjct: 876 NGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGP 935 Query: 962 K------GDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGP------------------ 997 + G KG PG PG G+P P + G + +GPPGP Sbjct: 936 QGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE 995 Query: 998 ---PGPPGPP---------GSISSSGQEIQQYISEYMQSDSIRSY-----LSGVQGPP-- 1038 PGPPGPP G + G Q IS +R + L G QG P Sbjct: 996 RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGL 1055 Query: 1039 ----GPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRD 1094 GP GPPGPV + GE S + + + R Sbjct: 1056 KGGEGPQGPPGPVGS-PGE-------------------------RGSAGTAGPIGLPGRP 1089 Query: 1095 DVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGIS--IGLPGPPG 1152 GP+GPPGP G G A G+ +GLPGP G Sbjct: 1090 -----------GPQGPPGPAGEKG---------APGEKGPQGPAGRDGVQGPVGLPGPAG 1129 Query: 1153 PPGLPGTSYEELLSLLRGSE-FRGIVGPPGPPGPPGIPGNVWS-----------SISVED 1200 P G PG ++ G + +G G GPPGPPG+ G V + + Sbjct: 1130 PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQG 1189 Query: 1201 LSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVR 1260 + G PGPPGP G G GPPG G EN D P Sbjct: 1190 MFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKG-------ENGD----------VGP--- 1229 Query: 1261 SFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGS 1320 +GPPGPPGP+GP G + D S S +G + G G Sbjct: 1230 ---MGPPGPPGPRGPQGPN---GADGPQGPPGSVGSVGGVGEKGEPGEAG---NPGPPGE 1280 Query: 1321 LGAGGAFGEAA--GDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAV 1378 G GG GE G+ GP G GP G G + G GN G +G F GD Sbjct: 1281 AGVGGPKGERGEKGEAGPPGA-AGPPGAKGPPGDDGP-KGNPGPVG--FPGD-------- 1328 Query: 1379 RVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQG 1438 GPPG+PGP G G+ G +G Sbjct: 1329 -------------------PGPPGEPGPAGQDGV---------------------GGDKG 1348 Query: 1439 PPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 G G+ G PGP G+ GP GPPG GPPG G +G +G+KG + AG Sbjct: 1349 EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAG 1396 Score = 434 bits (1117), Expect = e-121 Identities = 313/835 (37%), Positives = 355/835 (42%), Gaps = 227/835 (27%) Query: 567 GSPGPKG---DMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQR 623 G GPKG G PGP G G G G+PG G+PG QGPKG G G PG G G R Sbjct: 823 GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGAR 882 Query: 624 GREGPMGPRGEAGPPGS-GEKGERGAAGEPGPHG------PPGVPGSVGPKGSSGS---P 673 G G GPRG+ GP G G +G RG G+PGP G PPG PG GP+G G P Sbjct: 883 GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFP 942 Query: 674 GPQGPPGPVGLQGL---------------------------------------------- 687 GP+GPPGP G GL Sbjct: 943 GPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPP 1002 Query: 688 --RGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPA 745 GE GLPG G +G G PGP+G G+ GP GL G PG RGLPGA G PG KG GP Sbjct: 1003 GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQ 1062 Query: 746 GPDGHQGPRGEQ---------GLTGMPGIRGPPGPSGDPGKPGLTGPQGPQ--------- 787 GP G G GE+ GL G PG +GPPGP+G+ G PG GPQGP Sbjct: 1063 GPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV 1122 Query: 788 GLP------GTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPP------ 835 GLP G+PG G KGE G PG+ S+G GPPGPPG GP G P Sbjct: 1123 GLPGPAGPAGSPGEDGDKGEIGEPGQ-KGSKGDK--GENGPPGPPGLQGPVGAPGIAGGD 1179 Query: 836 GAPGPAGPAGL------------PGHQEVLNLQGPPGPPGPR------GPPGPSIPGPPG 877 G PGP G G+ PG + LQG PGPPG + GP GP PGPPG Sbjct: 1180 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP--PGPPG 1237 Query: 878 PRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGP---PGPPGPKGDQGPPGPRGHQGEQG 933 PRGP G G GP GPPGS S G PG PGPPG G GP G RG +GE G Sbjct: 1238 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG 1297 Query: 934 LPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGAL---------GIPSGPSEGG 984 PG + + GP G PGP G GD G PG PG G P + G Sbjct: 1298 PPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG 1357 Query: 985 SSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPP 1044 +GPPGPPG GPPG+ + G+ Q + +G +GPPG GP Sbjct: 1358 PPGPSGEAGPPGPPGKRGPPGAAGAEGR----------QGEKGAKGEAGAEGPPGKTGPV 1407 Query: 1045 GPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYL 1104 GP + G+ + + + +D Sbjct: 1408 GPQGPAG-----------------KPGPEGLRGIPGPVGEQGLPGAAGQDGP-------- 1442 Query: 1105 MGPRGPPGPPGASGD-GSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEE 1163 GP GPPG PG GD GS + L IGL GPPG G G Sbjct: 1443 PGPMGPPGLPGLKGDPGSKGEKGHPGL--------------IGLIGPPGEQGEKGD---- 1484 Query: 1164 LLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPP 1223 RG G G PG G GIPG AG PGPPG PGP Sbjct: 1485 -----RG--LPGTQGSPGAKGDGGIPG----------------PAGPLGPPGPPGLPGPQ 1521 Query: 1224 GPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGD 1278 GP+G G +G A + DS G PGPPG GPPG+ Sbjct: 1522 GPKGNKGSTGP----AGQKGDS-------------------GLPGPPGSPGPPGE 1553 Score = 420 bits (1080), Expect = e-117 Identities = 350/997 (35%), Positives = 411/997 (41%), Gaps = 221/997 (22%) Query: 590 PGIPGPL--------GHPGPQGPKGQKG--SVGDPGM--EGPMGQRGREGPMGPRGEAGP 637 PG+P GH G G KGQKG +V +PGM EGP G G G MGP G GP Sbjct: 415 PGVPAETDITETSINGH-GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGP 473 Query: 638 PGS-GEKGERGAAGEPGPHGPPGVPGSVGPK-------GSSGSPGP-------------- 675 G G+ G+RG G PG G G+PG G G GS GP Sbjct: 474 TGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQ 533 Query: 676 ------QGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGL 729 +GPPGP+GL G G VG PG G KG G PGP+G +G +GP G TG+PG RG Sbjct: 534 QARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGR 593 Query: 730 PGAVGE---PGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGP 786 PGA G PG GA G G DG G G++G G G +GPPGP GD G G G GP Sbjct: 594 PGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 653 Query: 787 QGLPGTPGRPGI---KGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGP---PGPPGAPGP 840 +GLPG G G+ +G PGAPG+ M V GPPGP G MGP PGPPG G Sbjct: 654 RGLPGEAGPRGLLGPRGTPGAPGQ------PGMAGVDGPPGPKGNMGPQGEPGPPGQQGN 707 Query: 841 AGPAGLPGHQEVLNLQGPPGPPGPRGPPG-PSIPGPPGPRGPPGEGLPGPPGPPGSFLSN 899 GP GLPG QGP GPPG +GP G P + G PG GPPG PG G G Sbjct: 708 PGPQGLPGP------QGPIGPPGEKGPQGKPGLAGLPGADGPPGH--PGKEGQSG----- 754 Query: 900 SETFLSGPPGPPGP---PGPKGDQGPPGPRG------HQGEQGLPGFSTSGSSSFGLNLQ 950 E GPPGP GP PGP+G +G G RG +GE G PGF GL Sbjct: 755 -EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK----GDMGLKGD 809 Query: 951 -------GPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGP 1003 GP G GP+GPKG G G PG PSG + G + V G PG PG GP Sbjct: 810 RGEVGQIGPRGEDGPEGPKGRAGPTGDPG----PSG--QAGEKGKLGVPGLPGYPGRQGP 863 Query: 1004 PGSIS------SSGQEIQQYISEYMQSDSIRSYLS--GVQGPPGPPGPPGPVTTITGETF 1055 GS ++G++ + ++ R G +G GP G PGP T G+ Sbjct: 864 KGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 923 Query: 1056 DYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPG 1115 G+ +D L Q G GPPGP G Sbjct: 924 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLP----GHPGQRGETGFQGKTGPPGPGG 979 Query: 1116 ASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPP---GLPGTSYEE--------- 1163 G + + R G PGPPGPP GLPG + +E Sbjct: 980 VVGPQGPTG-ETGPIGER------------GHPGPPGPPGEQGLPGAAGKEGAKGDPGPQ 1026 Query: 1164 -------------------LLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSY 1204 L +G GP GPPGP G PG S+ Sbjct: 1027 GISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA--------- 1077 Query: 1205 LHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIV 1264 TAG +PG PGP GPPGP G G G D + V Sbjct: 1078 -GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP--------------V 1122 Query: 1265 GPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAG 1324 G PGP GP G PG+ ++GS + G G G Sbjct: 1123 GLPGPAGPAGSPGED------------GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPV 1170 Query: 1325 GAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESM 1384 GA G A GD P GP G G + G G G G G + L E Sbjct: 1171 GAPGIAGGDGEP-----GPRGQQGMFGQKG-DEGARGFPGP--PGPIGLQGLPGPPGEKG 1222 Query: 1385 QRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKG 1444 + + GPPG PGP+GP G + QGPPG G Sbjct: 1223 ENGDV------GPMGPPGPPGPRGPQGPNGA------------------DGPQGPPGSVG 1258 Query: 1445 EMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGD 1481 +G G KG+ G AG PG PG G G KGE+G+KG+ Sbjct: 1259 SVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGE 1295 Score = 395 bits (1014), Expect = e-109 Identities = 225/493 (45%), Positives = 251/493 (50%), Gaps = 41/493 (8%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGR 625 +G PGP G+ G+PG KG +G G G+ GP+G PGP GP G G GD G G GQ+G Sbjct: 1092 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGS 1151 Query: 626 EGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGL 684 +G G G GPPG G G G AG G GP G G G KG G+ G GPPGP+GL Sbjct: 1152 KGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL 1211 Query: 685 QGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVG------EPGA 738 QGL G G G GD GPMGPPGP G +G +GP G G G G G+VG EPG Sbjct: 1212 QGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGE 1271 Query: 739 KGAMGP---AGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGR 795 G GP AG G +G RGE+G G PG GPPG G PG G G GP G PG PG Sbjct: 1272 AGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1331 Query: 796 PGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNL 855 PG G G G PGPPGP G GPPGPPG GP G AG G Q Sbjct: 1332 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGA 1391 Query: 856 QGPPGPPGPRGPPGPSIPGPPGPRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPPGPP 914 +G G GP G GP GP GP G PG EGL G PGP G GPPGP GPP Sbjct: 1392 KGEAGAEGPPGKTGPV--GPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPP 1449 Query: 915 GPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGAL 974 G G +G PG +G +G GL G GPPG QG KGD+G +PG Sbjct: 1450 GLPGLKGDPGSKGEKGHPGLIGLI---------------GPPGEQGEKGDRG---LPGTQ 1491 Query: 975 GIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGV 1034 G P +GG GPPGPPG PGP G + G + + SG+ Sbjct: 1492 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGS----------TGPAGQKGDSGL 1541 Query: 1035 QGPPGPPGPPGPV 1047 GPPG PGPPG V Sbjct: 1542 PGPPGSPGPPGEV 1554 Score = 387 bits (995), Expect = e-107 Identities = 267/717 (37%), Positives = 314/717 (43%), Gaps = 176/717 (24%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPG---------PLGHPGPQGPKGQKGS---VGD 613 RGS G +G G PGPKG G G PG PG P+G PGP+GP G G G Sbjct: 900 RGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGH 959 Query: 614 PGMEGPMGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPG---VPGSVGPKGS 669 PG G G +G+ GP GP G GP G +GE G G G PGP GPPG +PG+ G +G+ Sbjct: 960 PGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGA 1019 Query: 670 SGSPGPQG---PPGPVGLQGLRGEVGLPG------VKGDKGPMGPPGPKGDQGEKG---- 716 G PGPQG GP GL+G GE GLPG +KG +GP GPPGP G GE+G Sbjct: 1020 KGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGT 1079 Query: 717 --PRGLTGEPGMRGLPGAVGE---PGAKGAMGPAGPDGHQGP------------------ 753 P GL G PG +G PG GE PG KG GPAG DG QGP Sbjct: 1080 AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGD 1139 Query: 754 ---------------RGEQGLTGMPGIRGP------------PGPSGDPGKPGLTGPQGP 786 +GE G G PG++GP PGP G G G G +G Sbjct: 1140 KGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA 1199 Query: 787 QGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVP-GPPGPPGAMGPPGPPGAPGPAGPAG 845 +G PG PG G++G PG PG+ +G + P GPPGPPG GP GP GA GP GP G Sbjct: 1200 RGFPGPPGPIGLQGLPGPPGE----KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPG 1255 Query: 846 LPGHQEVLNLQGPPGPPGPRGPPG-------------------PSIPGPPGPRGPPGE-- 884 G + +G PG G GPPG P GPPG +GPPG+ Sbjct: 1256 SVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDG 1315 Query: 885 --------GLPGPPGPPGSFLSNSETFLSGP------PGPPGPPGPKGDQGPPGP---RG 927 G PG PGPPG + + G PG PGPPGP G+ GPPGP RG Sbjct: 1316 PKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRG 1375 Query: 928 HQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSS 987 G G G + +GPPG GP GP+G G PG G GIP E G Sbjct: 1376 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1435 Query: 988 TMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPV 1047 GPPGP GPPG PG G + ++ G G G GPPG Sbjct: 1436 AAGQDGPPGPMGPPGLPGLKGDPGSKGEK----------------GHPGLIGLIGPPGE- 1478 Query: 1048 TTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGP 1107 GE D + + G G+ + + L GP Sbjct: 1479 ---QGEKGDRGLPGTQGSPGAKGDG-GIPGPAGPLGPPGPPG--------------LPGP 1520 Query: 1108 RGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEEL 1164 +GP G G++G G S GLPGPPG PG PG + L Sbjct: 1521 QGPKGNKGSTGPA------------------GQKGDS-GLPGPPGSPGPPGEVIQPL 1558 Score = 250 bits (638), Expect = 8e-66 Identities = 261/814 (32%), Positives = 298/814 (36%), Gaps = 179/814 (21%) Query: 768 PPGPSGDPGKPGLTG-PQGPQGLPGTPGRPGIKGEPGA--PGKIVTSEGSSMLTVPGPPG 824 PP PG P T + G G G KGEP PG +V GPPG Sbjct: 408 PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVE----------GPPG 457 Query: 825 PPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGP------ 878 P G G GPPG GP GP G PG +GPPG PG G G +PGPPG Sbjct: 458 PAGPAGIMGPPGLQGPTGPPGDPGD------RGPPGRPGLPGADG--LPGPPGTMLMLPF 509 Query: 879 ------------------------------RGPPG----EGLPGPPGPPGSFLSNSETFL 904 RGPPG G PGP G PGS + Sbjct: 510 RYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGS------SGA 563 Query: 905 SGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGF----------STSGSSSF-GL------ 947 G G PGP GP+G QGPPGP G G++G PG G F GL Sbjct: 564 KGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 623 Query: 948 -------NLQGPPGPPGPQ---------GPKGDKGDPGVPGALGIPSGPSEGGSSSTMYV 991 QGPPGPPG GP+G G+ G G LG P G V Sbjct: 624 KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 683 Query: 992 SGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGP----- 1046 GPPGP G GP G GQ Q + L G QGP GPPG GP Sbjct: 684 DGPPGPKGNMGPQGEPGPPGQ----------QGNPGPQGLPGPQGPIGPPGEKGPQGKPG 733 Query: 1047 VTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMG 1106 + + G S G I V D VR + G Sbjct: 734 LAGLPGADGPPGHPGKEGQSG-EKGALGPPGPQGPIGYPGPRGVKGADGVRGL--KGSKG 790 Query: 1107 PRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEE-LL 1165 +G G PG GD L D E+ G GP G PG G + E+ L Sbjct: 791 EKGEDGFPGFKGDMGLKG-DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 849 Query: 1166 SLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGP 1225 + + G GP G G PG PG + G++ PGP G GP GP Sbjct: 850 GVPGLPGYPGRQGPKGSTGFPGFPG----------ANGEKGARGVAGKPGPRGQRGPTGP 899 Query: 1226 ------RGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDS 1279 RGP G G T + E P VG PGP GP GPPG Sbjct: 900 RGSRGARGPTGKPGPKGTSGGDGPPGPPGE-----RGPQGPQGPVGFPGPKGPPGPPGKD 954 Query: 1280 RLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAA--GDRGPY 1337 L H +RG + + G G +G G GE G+RG Sbjct: 955 GL-------------PGHPG--QRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP 999 Query: 1338 GTDIGPG--GGYGAAAEGGMYAGNG--GLLGADFAGDLDYNELAVRVSESMQRQGLLQGM 1393 G PG G GAA + G G G+ G D L + + GL G Sbjct: 1000 GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG- 1058 Query: 1394 AYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKG 1453 +GP G PGP G PG S TA + G QGPPG GE G PG KG Sbjct: 1059 ----EGPQGPPGPVGSPG-----ERGSAGTAGPIGLPGRPGP-QGPPGPAGEKGAPGEKG 1108 Query: 1454 DRGPA------GPPGHPGPPGPRGHKGEKGDKGD 1481 +GPA GP G PGP GP G GE GDKG+ Sbjct: 1109 PQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1142 Score = 248 bits (633), Expect = 3e-65 Identities = 138/278 (49%), Positives = 154/278 (55%), Gaps = 31/278 (11%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKG---QKGSVGDPGMEGPMGQR 623 G PG KG G GPKG+ G G PG PGP G PGP G G KG GDPG GP G Sbjct: 1303 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPS 1362 Query: 624 GREGPMGPRGEAGPPGS----GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGP- 678 G GP GP G+ GPPG+ G +GE+GA GE G GPPG G VGP+G +G PGP+G Sbjct: 1363 GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR 1422 Query: 679 --PGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEP 736 PGPVG QGL G G G G GP G PG KGD G KG +G PG+ GL G GE Sbjct: 1423 GIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKG---HPGLIGLIGPPGEQ 1479 Query: 737 GAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRP 796 G KG G G G G +G+ G I GP GP G PG PGL GPQGP+G G+ G Sbjct: 1480 GEKGDRGLPGTQGSPGAKGDGG------IPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA 1533 Query: 797 GIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGP 834 G KG+ G PG PG PGPPG + P P Sbjct: 1534 GQKGDSGLPGP------------PGSPGPPGEVIQPLP 1559 Score = 188 bits (478), Expect = 3e-47 Identities = 204/715 (28%), Positives = 247/715 (34%), Gaps = 193/715 (26%) Query: 878 PRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGD----------QGPPGPRG 927 P PP E PG P +ET ++G G G G KG+ +GPPGP G Sbjct: 405 PTSPPNEEFG--PGVPAE-TDITETSINGH-GAYGEKGQKGEPAVVEPGMLVEGPPGPAG 460 Query: 928 HQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSE----- 982 G G PG LQGP GPPG G +G G PG+PGA G+P P Sbjct: 461 PAGIMGPPG------------LQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 508 Query: 983 ---GGSSST-------------------MYVSGPPGP------PGPPGPPGSISSSGQEI 1014 GG S + + GPPGP PGP G PGS + G+ Sbjct: 509 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGES- 567 Query: 1015 QQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYG 1074 D GVQGPPGP G PG + G G Sbjct: 568 ---------GDPGPQGPRGVQGPPGPTGKPGKRGRPGAD-----------------GGRG 601 Query: 1075 VSLFSSSISSE--DILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSS 1132 + + D L L D + G RGP GPPG GD + D E+ Sbjct: 602 MPGEPGAKGDRGFDGLPGLPGDKGHR-------GERGPQGPPGPPGDDGMRGED-GEIGP 653 Query: 1133 RILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGP---------P 1183 R L + +G G PG PG PG + G+ GPPGP P Sbjct: 654 RGLPGEAGPRGLLGPRGTPGAPGQPGMA--------------GVDGPPGPKGNMGPQGEP 699 Query: 1184 GPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENS 1243 GPPG GN G +PGP GP GPPG +GP G G A+ Sbjct: 700 GPPGQQGN----------------PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGP 743 Query: 1244 DSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRR 1303 + +GPPGP GP G PG + D S Sbjct: 744 PGHPGK-----EGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFP 798 Query: 1304 GSSYSSSMSTGGGGAGSLGAGGAFGEAA--------GDRGPYGT-----DIGPGGGYGAA 1350 G + G G +G G G GD GP G +G G G Sbjct: 799 GFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYP 858 Query: 1351 AEGGMYAGNG--GLLGADFAGDLDYNELAVRVSESMQR--------------------QG 1388 G G G GA+ G+ +A + QR +G Sbjct: 859 GRQGPKGSTGFPGFPGAN--GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 916 Query: 1389 LLQGMA----------YTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTY----- 1433 G QGP G PGP+GPPG + FQ Sbjct: 917 TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 976 Query: 1434 -GAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGR 1487 G + GP G GE G G +G GP GPPG G PG G +G KGD G Q +G+ Sbjct: 977 PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1031 Score = 139 bits (349), Expect = 3e-32 Identities = 156/556 (28%), Positives = 189/556 (33%), Gaps = 147/556 (26%) Query: 957 GPQGPKGDKGDPGV--PGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEI 1014 G G KG KG+P V PG L + P G + M GPPG GP GPPG G Sbjct: 432 GAYGEKGQKGEPAVVEPGML-VEGPPGPAGPAGIM---GPPGLQGPTGPPGDPGDRGPP- 486 Query: 1015 QQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYG 1074 G G PG G PGP T+ F Y G Sbjct: 487 ------------------GRPGLPGADGLPGPPGTMLMLPFRYG---------------G 513 Query: 1075 VSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRI 1134 +IS+++ A + L+Q + RGPPGP Sbjct: 514 DGSKGPTISAQEAQA-------QAILQQARIALRGPPGP--------------------- 545 Query: 1135 LSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWS 1194 +GL G PGP G PG+S +G G PGP GP G+ G Sbjct: 546 ----------MGLTGRPGPVGGPGSSGA-----------KGESGDPGPQGPRGVQG---- 580 Query: 1195 SISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYL 1254 PPGP G PG RG PG G + R L Sbjct: 581 ---------------------PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG--FDGL 617 Query: 1255 TSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHS-RGSSSSSHSSSV-----RRGSSYS 1308 G GP GP GPPGD + D RG + + G+ Sbjct: 618 PGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQ 677 Query: 1309 SSMSTGGGGAGSLGAGGAFGEAA-----GDRGPYGTDIGPGGGYGAAAEGGMYA--GNGG 1361 M+ G G G G GE G+ GP G GP G G E G G G Sbjct: 678 PGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP-GPQGPIGPPGEKGPQGKPGLAG 736 Query: 1362 LLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSN 1421 L GAD E ++ G QGP G PGP+G G V + Sbjct: 737 LPGADGPPGHPGKEGQSGEKGALGPPG--------PQGPIGYPGPRGVKGADGVRGLKGS 788 Query: 1422 VTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGD 1481 D F PG KG+MG G +G+ G GP G GP GP+G G GD G Sbjct: 789 KGEKGEDGF---------PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 839 Query: 1482 QVYAGRRRRRSIAVKP 1497 AG + + + P Sbjct: 840 SGQAGEKGKLGVPGLP 855 Score = 105 bits (263), Expect = 3e-22 Identities = 62/131 (47%), Positives = 67/131 (51%), Gaps = 14/131 (10%) Query: 559 EQENGNLRGSPGPKGDMGS---PGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPG 615 EQ G GP G MG PG KGD G G G PG +G GP G +G+KG G PG Sbjct: 1430 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1489 Query: 616 MEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGP---KGSSGS 672 +G G +G G GP G GPP G G PGP GP G GS GP KG SG Sbjct: 1490 TQGSPGAKGDGGIPGPAGPLGPP--------GPPGLPGPQGPKGNKGSTGPAGQKGDSGL 1541 Query: 673 PGPQGPPGPVG 683 PGP G PGP G Sbjct: 1542 PGPPGSPGPPG 1552 Score = 33.9 bits (76), Expect = 1.2 Identities = 19/39 (48%), Positives = 22/39 (56%), Gaps = 9/39 (23%) Query: 566 RGSPGP---KGDMGSPGPKGDRGFPGTPGIPGPLGHPGP 601 +GS GP KGD G PGP PG+PG PG + P P Sbjct: 1527 KGSTGPAGQKGDSGLPGP------PGSPGPPGEVIQPLP 1559 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 493 bits (1269), Expect = e-139 Identities = 349/988 (35%), Positives = 419/988 (42%), Gaps = 211/988 (21%) Query: 559 EQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPG---PLGHPGPQGPKGQKGSVGDPG 615 +Q N +G PGP+G +G PG KG +G PG G+PG P GHPG +G G+KG++G PG Sbjct: 653 QQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPG 712 Query: 616 MEGPMGQ------------RGREGPMGPRGEAGPPG----SGEKGERGAAGEPGPHGPPG 659 +GP+G RG +G G +GE G PG G KG+RG G+ GP G G Sbjct: 713 PQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDG 772 Query: 660 VPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRG 719 G G G +G PGP G G G G+ G G PG +G KG G PG G GEKG RG Sbjct: 773 PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG 832 Query: 720 LTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPG 779 + G+PG RG G G G++GA GP G G +G G G G PG RGP GP G G PG Sbjct: 833 VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG 892 Query: 780 LTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPG 839 GP GP G G PG PG +GE G GK ++ GP G G +G G PG PG Sbjct: 893 PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 952 Query: 840 PAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS-IPGPPGPRGPPG----------EGLPG 888 P G GLPG +G PGP G G GP+ + G PG RG PG EG G Sbjct: 953 PPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1012 Query: 889 PPGPPGSFLSNSETFLSGP------PGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGS 942 PPGP GS +GP PGP GPPGP G++G PG +G QG G G Sbjct: 1013 PPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG------ 1066 Query: 943 SSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPG--- 999 +QGP G PGP GP G G+ G G +G P + GS +GPPGPPG Sbjct: 1067 ------VQGPVGLPGPAGPAGSPGEDGDKGEIG---EPGQKGSKGDKGENGPPGPPGLQG 1117 Query: 1000 PPGPPGSISSSGQ---EIQQYISEYMQSDSIRSYLSGVQGPPGP------PGPPGPVTTI 1050 P G PG G+ QQ + + R G GPPGP PGPPG Sbjct: 1118 PVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR----GFPGPPGPIGLQGLPGPPGE---- 1169 Query: 1051 TGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGP 1110 GE D +GP GP Sbjct: 1170 KGENGD------------------------------------------------VGPMGP 1181 Query: 1111 PGPPGASGDGSLLSLDYAELSSRILSYMSSSGIS-----IGLPGPPGPPGLPGTSYEELL 1165 PGPPG G D + + + G G PGPPG G+ G E Sbjct: 1182 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE--- 1238 Query: 1166 SLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGP 1225 RG +G GPPG GPPG G G PG PGPPG PGP Sbjct: 1239 ---RGE--KGEAGPPGAAGPPGAKGPPGDD-------GPKGNPGPVGFPGDPGPPGEPGP 1286 Query: 1226 RGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTD 1285 G GV G E+ D + P S GPPGPPG +GPPG + Sbjct: 1287 AGQDGVGGD----KGEDGDPGQP-------GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1335 Query: 1286 ASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGE-----AAGDRGPYGTD 1340 + + + G + G G G G GE AAG GP G Sbjct: 1336 GEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGP- 1394 Query: 1341 IGPGGGYGAAAEGGMYA--GNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQ 1398 +GP G G + G G+ GL+G + Sbjct: 1395 MGPPGLPGLKGDPGSKGEKGHPGLIG--------------------------------LI 1422 Query: 1399 GPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPA 1458 GPPG+ G +G G+ QG PG KG+ G PGP G GP Sbjct: 1423 GPPGEQGEKGDRGLP---------------------GTQGSPGAKGDGGIPGPAGPLGPP 1461 Query: 1459 GPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 GPPG PGP GP+G+KG G G + +G Sbjct: 1462 GPPGLPGPQGPKGNKGSTGPAGQKGDSG 1489 Score = 481 bits (1238), Expect = e-135 Identities = 377/1068 (35%), Positives = 440/1068 (41%), Gaps = 281/1068 (26%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPK-------GQKGSVGDP--- 614 + G PG +G G PG GDRG PG PG+PG G PGP G G GS G Sbjct: 413 IMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISA 472 Query: 615 -----------------GMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHG- 656 G GPMG GR GP+G GP SG KGE G G GP G Sbjct: 473 QEAQAQAILQQARIALRGPPGPMGLTGRPGPVG-----GPGSSGAKGESGDPGPQGPRGV 527 Query: 657 --PPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKG------PMGPPGP 708 PPG G G +G G+ G +G PG G +G RG GLPG+ GDKG P GPPGP Sbjct: 528 QGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGP 587 Query: 709 KGDQG------EKGPRGLTGEPGMRGL------PGAVGEPGAKGAMGPAGPDGHQGPRGE 756 GD G E GPRGL GE G RGL PGA G+PG G GP GP G+ GP+GE Sbjct: 588 PGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE 647 Query: 757 QGLTGMPGIRGPPGPSGDPGKPGLTGP---QGPQGLPGTPGRPGIKGEPGAPGKIVTSEG 813 G PG +G PGP G PG G GP +GPQG PG G PG G PG PGK S Sbjct: 648 ---PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGE 704 Query: 814 SSMLTVPGPPGPPGAMGPPGPPGA------------------PGPAGPAGLPGHQEVLNL 855 L PGP GP G GP G GA PG G GL G + + Sbjct: 705 KGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 764 Query: 856 QGPPGPPGPRGPPGPSIP-GPPGPRGPPGE----GLPGPPGPPGSFLSNSETFLSGPPGP 910 GP G GP GP G + P G PGP G GE G+PG PG PG T G PG Sbjct: 765 IGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 824 Query: 911 ---------PGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGP 961 G PGP+G +GP GPRG +G +G G +S G GPPG GPQGP Sbjct: 825 NGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGP 884 Query: 962 K------GDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGP------------------ 997 + G KG PG PG G+P P + G + +GPPGP Sbjct: 885 QGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE 944 Query: 998 ---PGPPGPP---------GSISSSGQEIQQYISEYMQSDSIRSY-----LSGVQGPP-- 1038 PGPPGPP G + G Q IS +R + L G QG P Sbjct: 945 RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGL 1004 Query: 1039 ----GPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRD 1094 GP GPPGPV + GE S + + + R Sbjct: 1005 KGGEGPQGPPGPVGS-PGE-------------------------RGSAGTAGPIGLPGRP 1038 Query: 1095 DVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGIS--IGLPGPPG 1152 GP+GPPGP G G A G+ +GLPGP G Sbjct: 1039 -----------GPQGPPGPAGEKG---------APGEKGPQGPAGRDGVQGPVGLPGPAG 1078 Query: 1153 PPGLPGTSYEELLSLLRGSE-FRGIVGPPGPPGPPGIPGNVWS-----------SISVED 1200 P G PG ++ G + +G G GPPGPPG+ G V + + Sbjct: 1079 PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQG 1138 Query: 1201 LSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVR 1260 + G PGPPGP G G GPPG G EN D P Sbjct: 1139 MFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKG-------ENGD----------VGP--- 1178 Query: 1261 SFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGS 1320 +GPPGPPGP+GP G + D S S +G + G G Sbjct: 1179 ---MGPPGPPGPRGPQGPN---GADGPQGPPGSVGSVGGVGEKGEPGEAG---NPGPPGE 1229 Query: 1321 LGAGGAFGEAA--GDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAV 1378 G GG GE G+ GP G GP G G + G GN G +G F GD Sbjct: 1230 AGVGGPKGERGEKGEAGPPGA-AGPPGAKGPPGDDGP-KGNPGPVG--FPGD-------- 1277 Query: 1379 RVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQG 1438 GPPG+PGP G G+ G +G Sbjct: 1278 -------------------PGPPGEPGPAGQDGV---------------------GGDKG 1297 Query: 1439 PPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 G G+ G PGP G+ GP GPPG GPPG G +G +G+KG + AG Sbjct: 1298 EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAG 1345 Score = 434 bits (1117), Expect = e-121 Identities = 313/835 (37%), Positives = 355/835 (42%), Gaps = 227/835 (27%) Query: 567 GSPGPKG---DMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQR 623 G GPKG G PGP G G G G+PG G+PG QGPKG G G PG G G R Sbjct: 772 GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGAR 831 Query: 624 GREGPMGPRGEAGPPGS-GEKGERGAAGEPGPHG------PPGVPGSVGPKGSSGS---P 673 G G GPRG+ GP G G +G RG G+PGP G PPG PG GP+G G P Sbjct: 832 GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFP 891 Query: 674 GPQGPPGPVGLQGL---------------------------------------------- 687 GP+GPPGP G GL Sbjct: 892 GPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPP 951 Query: 688 --RGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPA 745 GE GLPG G +G G PGP+G G+ GP GL G PG RGLPGA G PG KG GP Sbjct: 952 GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQ 1011 Query: 746 GPDGHQGPRGEQ---------GLTGMPGIRGPPGPSGDPGKPGLTGPQGPQ--------- 787 GP G G GE+ GL G PG +GPPGP+G+ G PG GPQGP Sbjct: 1012 GPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV 1071 Query: 788 GLP------GTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPP------ 835 GLP G+PG G KGE G PG+ S+G GPPGPPG GP G P Sbjct: 1072 GLPGPAGPAGSPGEDGDKGEIGEPGQ-KGSKGDK--GENGPPGPPGLQGPVGAPGIAGGD 1128 Query: 836 GAPGPAGPAGL------------PGHQEVLNLQGPPGPPGPR------GPPGPSIPGPPG 877 G PGP G G+ PG + LQG PGPPG + GP GP PGPPG Sbjct: 1129 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP--PGPPG 1186 Query: 878 PRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGP---PGPPGPKGDQGPPGPRGHQGEQG 933 PRGP G G GP GPPGS S G PG PGPPG G GP G RG +GE G Sbjct: 1187 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG 1246 Query: 934 LPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGAL---------GIPSGPSEGG 984 PG + + GP G PGP G GD G PG PG G P + G Sbjct: 1247 PPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG 1306 Query: 985 SSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPP 1044 +GPPGPPG GPPG+ + G+ Q + +G +GPPG GP Sbjct: 1307 PPGPSGEAGPPGPPGKRGPPGAAGAEGR----------QGEKGAKGEAGAEGPPGKTGPV 1356 Query: 1045 GPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYL 1104 GP + G+ + + + +D Sbjct: 1357 GPQGPAG-----------------KPGPEGLRGIPGPVGEQGLPGAAGQDGP-------- 1391 Query: 1105 MGPRGPPGPPGASGD-GSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEE 1163 GP GPPG PG GD GS + L IGL GPPG G G Sbjct: 1392 PGPMGPPGLPGLKGDPGSKGEKGHPGL--------------IGLIGPPGEQGEKGD---- 1433 Query: 1164 LLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPP 1223 RG G G PG G GIPG AG PGPPG PGP Sbjct: 1434 -----RG--LPGTQGSPGAKGDGGIPG----------------PAGPLGPPGPPGLPGPQ 1470 Query: 1224 GPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGD 1278 GP+G G +G A + DS G PGPPG GPPG+ Sbjct: 1471 GPKGNKGSTGP----AGQKGDS-------------------GLPGPPGSPGPPGE 1502 Score = 420 bits (1080), Expect = e-117 Identities = 350/997 (35%), Positives = 411/997 (41%), Gaps = 221/997 (22%) Query: 590 PGIPGPL--------GHPGPQGPKGQKG--SVGDPGM--EGPMGQRGREGPMGPRGEAGP 637 PG+P GH G G KGQKG +V +PGM EGP G G G MGP G GP Sbjct: 364 PGVPAETDITETSINGH-GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGP 422 Query: 638 PGS-GEKGERGAAGEPGPHGPPGVPGSVGPK-------GSSGSPGP-------------- 675 G G+ G+RG G PG G G+PG G G GS GP Sbjct: 423 TGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQ 482 Query: 676 ------QGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGL 729 +GPPGP+GL G G VG PG G KG G PGP+G +G +GP G TG+PG RG Sbjct: 483 QARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGR 542 Query: 730 PGAVGE---PGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGP 786 PGA G PG GA G G DG G G++G G G +GPPGP GD G G G GP Sbjct: 543 PGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 602 Query: 787 QGLPGTPGRPGI---KGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGP---PGPPGAPGP 840 +GLPG G G+ +G PGAPG+ M V GPPGP G MGP PGPPG G Sbjct: 603 RGLPGEAGPRGLLGPRGTPGAPGQ------PGMAGVDGPPGPKGNMGPQGEPGPPGQQGN 656 Query: 841 AGPAGLPGHQEVLNLQGPPGPPGPRGPPG-PSIPGPPGPRGPPGEGLPGPPGPPGSFLSN 899 GP GLPG QGP GPPG +GP G P + G PG GPPG PG G G Sbjct: 657 PGPQGLPGP------QGPIGPPGEKGPQGKPGLAGLPGADGPPGH--PGKEGQSG----- 703 Query: 900 SETFLSGPPGPPGP---PGPKGDQGPPGPRG------HQGEQGLPGFSTSGSSSFGLNLQ 950 E GPPGP GP PGP+G +G G RG +GE G PGF GL Sbjct: 704 -EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK----GDMGLKGD 758 Query: 951 -------GPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGP 1003 GP G GP+GPKG G G PG PSG + G + V G PG PG GP Sbjct: 759 RGEVGQIGPRGEDGPEGPKGRAGPTGDPG----PSG--QAGEKGKLGVPGLPGYPGRQGP 812 Query: 1004 PGSIS------SSGQEIQQYISEYMQSDSIRSYLS--GVQGPPGPPGPPGPVTTITGETF 1055 GS ++G++ + ++ R G +G GP G PGP T G+ Sbjct: 813 KGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 872 Query: 1056 DYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPG 1115 G+ +D L Q G GPPGP G Sbjct: 873 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLP----GHPGQRGETGFQGKTGPPGPGG 928 Query: 1116 ASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPP---GLPGTSYEE--------- 1163 G + + R G PGPPGPP GLPG + +E Sbjct: 929 VVGPQGPTG-ETGPIGER------------GHPGPPGPPGEQGLPGAAGKEGAKGDPGPQ 975 Query: 1164 -------------------LLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSY 1204 L +G GP GPPGP G PG S+ Sbjct: 976 GISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA--------- 1026 Query: 1205 LHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIV 1264 TAG +PG PGP GPPGP G G G D + V Sbjct: 1027 -GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP--------------V 1071 Query: 1265 GPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAG 1324 G PGP GP G PG+ ++GS + G G G Sbjct: 1072 GLPGPAGPAGSPGED------------GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPV 1119 Query: 1325 GAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESM 1384 GA G A GD P GP G G + G G G G G + L E Sbjct: 1120 GAPGIAGGDGEP-----GPRGQQGMFGQKG-DEGARGFPGP--PGPIGLQGLPGPPGEKG 1171 Query: 1385 QRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKG 1444 + + GPPG PGP+GP G + QGPPG G Sbjct: 1172 ENGDV------GPMGPPGPPGPRGPQGPNGA------------------DGPQGPPGSVG 1207 Query: 1445 EMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGD 1481 +G G KG+ G AG PG PG G G KGE+G+KG+ Sbjct: 1208 SVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGE 1244 Score = 395 bits (1014), Expect = e-109 Identities = 225/493 (45%), Positives = 251/493 (50%), Gaps = 41/493 (8%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGR 625 +G PGP G+ G+PG KG +G G G+ GP+G PGP GP G G GD G G GQ+G Sbjct: 1041 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGS 1100 Query: 626 EGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGL 684 +G G G GPPG G G G AG G GP G G G KG G+ G GPPGP+GL Sbjct: 1101 KGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL 1160 Query: 685 QGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVG------EPGA 738 QGL G G G GD GPMGPPGP G +G +GP G G G G G+VG EPG Sbjct: 1161 QGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGE 1220 Query: 739 KGAMGP---AGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGR 795 G GP AG G +G RGE+G G PG GPPG G PG G G GP G PG PG Sbjct: 1221 AGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1280 Query: 796 PGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNL 855 PG G G G PGPPGP G GPPGPPG GP G AG G Q Sbjct: 1281 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGA 1340 Query: 856 QGPPGPPGPRGPPGPSIPGPPGPRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPPGPP 914 +G G GP G GP GP GP G PG EGL G PGP G GPPGP GPP Sbjct: 1341 KGEAGAEGPPGKTGPV--GPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPP 1398 Query: 915 GPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGAL 974 G G +G PG +G +G GL G GPPG QG KGD+G +PG Sbjct: 1399 GLPGLKGDPGSKGEKGHPGLIGLI---------------GPPGEQGEKGDRG---LPGTQ 1440 Query: 975 GIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGV 1034 G P +GG GPPGPPG PGP G + G + + SG+ Sbjct: 1441 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGS----------TGPAGQKGDSGL 1490 Query: 1035 QGPPGPPGPPGPV 1047 GPPG PGPPG V Sbjct: 1491 PGPPGSPGPPGEV 1503 Score = 387 bits (995), Expect = e-107 Identities = 267/717 (37%), Positives = 314/717 (43%), Gaps = 176/717 (24%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPG---------PLGHPGPQGPKGQKGS---VGD 613 RGS G +G G PGPKG G G PG PG P+G PGP+GP G G G Sbjct: 849 RGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGH 908 Query: 614 PGMEGPMGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPG---VPGSVGPKGS 669 PG G G +G+ GP GP G GP G +GE G G G PGP GPPG +PG+ G +G+ Sbjct: 909 PGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGA 968 Query: 670 SGSPGPQG---PPGPVGLQGLRGEVGLPG------VKGDKGPMGPPGPKGDQGEKG---- 716 G PGPQG GP GL+G GE GLPG +KG +GP GPPGP G GE+G Sbjct: 969 KGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGT 1028 Query: 717 --PRGLTGEPGMRGLPGAVGE---PGAKGAMGPAGPDGHQGP------------------ 753 P GL G PG +G PG GE PG KG GPAG DG QGP Sbjct: 1029 AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGD 1088 Query: 754 ---------------RGEQGLTGMPGIRGP------------PGPSGDPGKPGLTGPQGP 786 +GE G G PG++GP PGP G G G G +G Sbjct: 1089 KGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA 1148 Query: 787 QGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVP-GPPGPPGAMGPPGPPGAPGPAGPAG 845 +G PG PG G++G PG PG+ +G + P GPPGPPG GP GP GA GP GP G Sbjct: 1149 RGFPGPPGPIGLQGLPGPPGE----KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPG 1204 Query: 846 LPGHQEVLNLQGPPGPPGPRGPPG-------------------PSIPGPPGPRGPPGE-- 884 G + +G PG G GPPG P GPPG +GPPG+ Sbjct: 1205 SVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDG 1264 Query: 885 --------GLPGPPGPPGSFLSNSETFLSGP------PGPPGPPGPKGDQGPPGP---RG 927 G PG PGPPG + + G PG PGPPGP G+ GPPGP RG Sbjct: 1265 PKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRG 1324 Query: 928 HQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSS 987 G G G + +GPPG GP GP+G G PG G GIP E G Sbjct: 1325 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1384 Query: 988 TMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPV 1047 GPPGP GPPG PG G + ++ G G G GPPG Sbjct: 1385 AAGQDGPPGPMGPPGLPGLKGDPGSKGEK----------------GHPGLIGLIGPPGE- 1427 Query: 1048 TTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGP 1107 GE D + + G G+ + + L GP Sbjct: 1428 ---QGEKGDRGLPGTQGSPGAKGDG-GIPGPAGPLGPPGPPG--------------LPGP 1469 Query: 1108 RGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEEL 1164 +GP G G++G G S GLPGPPG PG PG + L Sbjct: 1470 QGPKGNKGSTGPA------------------GQKGDS-GLPGPPGSPGPPGEVIQPL 1507 Score = 250 bits (638), Expect = 8e-66 Identities = 261/814 (32%), Positives = 298/814 (36%), Gaps = 179/814 (21%) Query: 768 PPGPSGDPGKPGLTG-PQGPQGLPGTPGRPGIKGEPGA--PGKIVTSEGSSMLTVPGPPG 824 PP PG P T + G G G KGEP PG +V GPPG Sbjct: 357 PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVE----------GPPG 406 Query: 825 PPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGP------ 878 P G G GPPG GP GP G PG +GPPG PG G G +PGPPG Sbjct: 407 PAGPAGIMGPPGLQGPTGPPGDPGD------RGPPGRPGLPGADG--LPGPPGTMLMLPF 458 Query: 879 ------------------------------RGPPG----EGLPGPPGPPGSFLSNSETFL 904 RGPPG G PGP G PGS + Sbjct: 459 RYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGS------SGA 512 Query: 905 SGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGF----------STSGSSSF-GL------ 947 G G PGP GP+G QGPPGP G G++G PG G F GL Sbjct: 513 KGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 572 Query: 948 -------NLQGPPGPPGPQ---------GPKGDKGDPGVPGALGIPSGPSEGGSSSTMYV 991 QGPPGPPG GP+G G+ G G LG P G V Sbjct: 573 KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 632 Query: 992 SGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGP----- 1046 GPPGP G GP G GQ Q + L G QGP GPPG GP Sbjct: 633 DGPPGPKGNMGPQGEPGPPGQ----------QGNPGPQGLPGPQGPIGPPGEKGPQGKPG 682 Query: 1047 VTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMG 1106 + + G S G I V D VR + G Sbjct: 683 LAGLPGADGPPGHPGKEGQSG-EKGALGPPGPQGPIGYPGPRGVKGADGVRGL--KGSKG 739 Query: 1107 PRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEE-LL 1165 +G G PG GD L D E+ G GP G PG G + E+ L Sbjct: 740 EKGEDGFPGFKGDMGLKG-DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 798 Query: 1166 SLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGP 1225 + + G GP G G PG PG + G++ PGP G GP GP Sbjct: 799 GVPGLPGYPGRQGPKGSTGFPGFPG----------ANGEKGARGVAGKPGPRGQRGPTGP 848 Query: 1226 ------RGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDS 1279 RGP G G T + E P VG PGP GP GPPG Sbjct: 849 RGSRGARGPTGKPGPKGTSGGDGPPGPPGE-----RGPQGPQGPVGFPGPKGPPGPPGKD 903 Query: 1280 RLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAA--GDRGPY 1337 L H +RG + + G G +G G GE G+RG Sbjct: 904 GL-------------PGHPG--QRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP 948 Query: 1338 GTDIGPG--GGYGAAAEGGMYAGNG--GLLGADFAGDLDYNELAVRVSESMQRQGLLQGM 1393 G PG G GAA + G G G+ G D L + + GL G Sbjct: 949 GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG- 1007 Query: 1394 AYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKG 1453 +GP G PGP G PG S TA + G QGPPG GE G PG KG Sbjct: 1008 ----EGPQGPPGPVGSPG-----ERGSAGTAGPIGLPGRPGP-QGPPGPAGEKGAPGEKG 1057 Query: 1454 DRGPA------GPPGHPGPPGPRGHKGEKGDKGD 1481 +GPA GP G PGP GP G GE GDKG+ Sbjct: 1058 PQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1091 Score = 248 bits (633), Expect = 3e-65 Identities = 138/278 (49%), Positives = 154/278 (55%), Gaps = 31/278 (11%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKG---QKGSVGDPGMEGPMGQR 623 G PG KG G GPKG+ G G PG PGP G PGP G G KG GDPG GP G Sbjct: 1252 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPS 1311 Query: 624 GREGPMGPRGEAGPPGS----GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGP- 678 G GP GP G+ GPPG+ G +GE+GA GE G GPPG G VGP+G +G PGP+G Sbjct: 1312 GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR 1371 Query: 679 --PGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEP 736 PGPVG QGL G G G G GP G PG KGD G KG +G PG+ GL G GE Sbjct: 1372 GIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKG---HPGLIGLIGPPGEQ 1428 Query: 737 GAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRP 796 G KG G G G G +G+ G I GP GP G PG PGL GPQGP+G G+ G Sbjct: 1429 GEKGDRGLPGTQGSPGAKGDGG------IPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA 1482 Query: 797 GIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGP 834 G KG+ G PG PG PGPPG + P P Sbjct: 1483 GQKGDSGLPGP------------PGSPGPPGEVIQPLP 1508 Score = 188 bits (478), Expect = 3e-47 Identities = 204/715 (28%), Positives = 247/715 (34%), Gaps = 193/715 (26%) Query: 878 PRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGD----------QGPPGPRG 927 P PP E PG P +ET ++G G G G KG+ +GPPGP G Sbjct: 354 PTSPPNEEFG--PGVPAE-TDITETSINGH-GAYGEKGQKGEPAVVEPGMLVEGPPGPAG 409 Query: 928 HQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSE----- 982 G G PG LQGP GPPG G +G G PG+PGA G+P P Sbjct: 410 PAGIMGPPG------------LQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 457 Query: 983 ---GGSSST-------------------MYVSGPPGP------PGPPGPPGSISSSGQEI 1014 GG S + + GPPGP PGP G PGS + G+ Sbjct: 458 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGES- 516 Query: 1015 QQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYG 1074 D GVQGPPGP G PG + G G Sbjct: 517 ---------GDPGPQGPRGVQGPPGPTGKPGKRGRPGAD-----------------GGRG 550 Query: 1075 VSLFSSSISSE--DILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSS 1132 + + D L L D + G RGP GPPG GD + D E+ Sbjct: 551 MPGEPGAKGDRGFDGLPGLPGDKGHR-------GERGPQGPPGPPGDDGMRGED-GEIGP 602 Query: 1133 RILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGP---------P 1183 R L + +G G PG PG PG + G+ GPPGP P Sbjct: 603 RGLPGEAGPRGLLGPRGTPGAPGQPGMA--------------GVDGPPGPKGNMGPQGEP 648 Query: 1184 GPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENS 1243 GPPG GN G +PGP GP GPPG +GP G G A+ Sbjct: 649 GPPGQQGN----------------PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGP 692 Query: 1244 DSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRR 1303 + +GPPGP GP G PG + D S Sbjct: 693 PGHPGK-----EGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFP 747 Query: 1304 GSSYSSSMSTGGGGAGSLGAGGAFGEAA--------GDRGPYGT-----DIGPGGGYGAA 1350 G + G G +G G G GD GP G +G G G Sbjct: 748 GFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYP 807 Query: 1351 AEGGMYAGNG--GLLGADFAGDLDYNELAVRVSESMQR--------------------QG 1388 G G G GA+ G+ +A + QR +G Sbjct: 808 GRQGPKGSTGFPGFPGAN--GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 865 Query: 1389 LLQGMA----------YTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTY----- 1433 G QGP G PGP+GPPG + FQ Sbjct: 866 TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 925 Query: 1434 -GAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGR 1487 G + GP G GE G G +G GP GPPG G PG G +G KGD G Q +G+ Sbjct: 926 PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 980 Score = 139 bits (349), Expect = 3e-32 Identities = 156/556 (28%), Positives = 189/556 (33%), Gaps = 147/556 (26%) Query: 957 GPQGPKGDKGDPGV--PGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEI 1014 G G KG KG+P V PG L + P G + M GPPG GP GPPG G Sbjct: 381 GAYGEKGQKGEPAVVEPGML-VEGPPGPAGPAGIM---GPPGLQGPTGPPGDPGDRGPP- 435 Query: 1015 QQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYG 1074 G G PG G PGP T+ F Y G Sbjct: 436 ------------------GRPGLPGADGLPGPPGTMLMLPFRYG---------------G 462 Query: 1075 VSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRI 1134 +IS+++ A + L+Q + RGPPGP Sbjct: 463 DGSKGPTISAQEAQA-------QAILQQARIALRGPPGP--------------------- 494 Query: 1135 LSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWS 1194 +GL G PGP G PG+S +G G PGP GP G+ G Sbjct: 495 ----------MGLTGRPGPVGGPGSSGA-----------KGESGDPGPQGPRGVQG---- 529 Query: 1195 SISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYL 1254 PPGP G PG RG PG G + R L Sbjct: 530 ---------------------PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG--FDGL 566 Query: 1255 TSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHS-RGSSSSSHSSSV-----RRGSSYS 1308 G GP GP GPPGD + D RG + + G+ Sbjct: 567 PGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQ 626 Query: 1309 SSMSTGGGGAGSLGAGGAFGEAA-----GDRGPYGTDIGPGGGYGAAAEGGMYA--GNGG 1361 M+ G G G G GE G+ GP G GP G G E G G G Sbjct: 627 PGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP-GPQGPIGPPGEKGPQGKPGLAG 685 Query: 1362 LLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSN 1421 L GAD E ++ G QGP G PGP+G G V + Sbjct: 686 LPGADGPPGHPGKEGQSGEKGALGPPG--------PQGPIGYPGPRGVKGADGVRGLKGS 737 Query: 1422 VTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGD 1481 D F PG KG+MG G +G+ G GP G GP GP+G G GD G Sbjct: 738 KGEKGEDGF---------PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 788 Query: 1482 QVYAGRRRRRSIAVKP 1497 AG + + + P Sbjct: 789 SGQAGEKGKLGVPGLP 804 Score = 105 bits (263), Expect = 3e-22 Identities = 62/131 (47%), Positives = 67/131 (51%), Gaps = 14/131 (10%) Query: 559 EQENGNLRGSPGPKGDMGS---PGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPG 615 EQ G GP G MG PG KGD G G G PG +G GP G +G+KG G PG Sbjct: 1379 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1438 Query: 616 MEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGP---KGSSGS 672 +G G +G G GP G GPP G G PGP GP G GS GP KG SG Sbjct: 1439 TQGSPGAKGDGGIPGPAGPLGPP--------GPPGLPGPQGPKGNKGSTGPAGQKGDSGL 1490 Query: 673 PGPQGPPGPVG 683 PGP G PGP G Sbjct: 1491 PGPPGSPGPPG 1501 Score = 33.9 bits (76), Expect = 1.2 Identities = 19/39 (48%), Positives = 22/39 (56%), Gaps = 9/39 (23%) Query: 566 RGSPGP---KGDMGSPGPKGDRGFPGTPGIPGPLGHPGP 601 +GS GP KGD G PGP PG+PG PG + P P Sbjct: 1476 KGSTGPAGQKGDSGLPGP------PGSPGPPGEVIQPLP 1508 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 493 bits (1269), Expect = e-139 Identities = 349/988 (35%), Positives = 419/988 (42%), Gaps = 211/988 (21%) Query: 559 EQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPG---PLGHPGPQGPKGQKGSVGDPG 615 +Q N +G PGP+G +G PG KG +G PG G+PG P GHPG +G G+KG++G PG Sbjct: 692 QQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPG 751 Query: 616 MEGPMGQ------------RGREGPMGPRGEAGPPG----SGEKGERGAAGEPGPHGPPG 659 +GP+G RG +G G +GE G PG G KG+RG G+ GP G G Sbjct: 752 PQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDG 811 Query: 660 VPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRG 719 G G G +G PGP G G G G+ G G PG +G KG G PG G GEKG RG Sbjct: 812 PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG 871 Query: 720 LTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPG 779 + G+PG RG G G G++GA GP G G +G G G G PG RGP GP G G PG Sbjct: 872 VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPG 931 Query: 780 LTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPG 839 GP GP G G PG PG +GE G GK ++ GP G G +G G PG PG Sbjct: 932 PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 991 Query: 840 PAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS-IPGPPGPRGPPG----------EGLPG 888 P G GLPG +G PGP G G GP+ + G PG RG PG EG G Sbjct: 992 PPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1051 Query: 889 PPGPPGSFLSNSETFLSGP------PGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGS 942 PPGP GS +GP PGP GPPGP G++G PG +G QG G G Sbjct: 1052 PPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG------ 1105 Query: 943 SSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPG--- 999 +QGP G PGP GP G G+ G G +G P + GS +GPPGPPG Sbjct: 1106 ------VQGPVGLPGPAGPAGSPGEDGDKGEIG---EPGQKGSKGDKGENGPPGPPGLQG 1156 Query: 1000 PPGPPGSISSSGQ---EIQQYISEYMQSDSIRSYLSGVQGPPGP------PGPPGPVTTI 1050 P G PG G+ QQ + + R G GPPGP PGPPG Sbjct: 1157 PVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR----GFPGPPGPIGLQGLPGPPGE---- 1208 Query: 1051 TGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGP 1110 GE D +GP GP Sbjct: 1209 KGENGD------------------------------------------------VGPMGP 1220 Query: 1111 PGPPGASGDGSLLSLDYAELSSRILSYMSSSGIS-----IGLPGPPGPPGLPGTSYEELL 1165 PGPPG G D + + + G G PGPPG G+ G E Sbjct: 1221 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE--- 1277 Query: 1166 SLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGP 1225 RG +G GPPG GPPG G G PG PGPPG PGP Sbjct: 1278 ---RGE--KGEAGPPGAAGPPGAKGPPGDD-------GPKGNPGPVGFPGDPGPPGEPGP 1325 Query: 1226 RGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTD 1285 G GV G E+ D + P S GPPGPPG +GPPG + Sbjct: 1326 AGQDGVGGD----KGEDGDPGQP-------GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1374 Query: 1286 ASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGE-----AAGDRGPYGTD 1340 + + + G + G G G G GE AAG GP G Sbjct: 1375 GEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGP- 1433 Query: 1341 IGPGGGYGAAAEGGMYA--GNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQ 1398 +GP G G + G G+ GL+G + Sbjct: 1434 MGPPGLPGLKGDPGSKGEKGHPGLIG--------------------------------LI 1461 Query: 1399 GPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPA 1458 GPPG+ G +G G+ QG PG KG+ G PGP G GP Sbjct: 1462 GPPGEQGEKGDRGLP---------------------GTQGSPGAKGDGGIPGPAGPLGPP 1500 Query: 1459 GPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 GPPG PGP GP+G+KG G G + +G Sbjct: 1501 GPPGLPGPQGPKGNKGSTGPAGQKGDSG 1528 Score = 481 bits (1238), Expect = e-135 Identities = 377/1068 (35%), Positives = 440/1068 (41%), Gaps = 281/1068 (26%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPK-------GQKGSVGDP--- 614 + G PG +G G PG GDRG PG PG+PG G PGP G G GS G Sbjct: 452 IMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISA 511 Query: 615 -----------------GMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHG- 656 G GPMG GR GP+G GP SG KGE G G GP G Sbjct: 512 QEAQAQAILQQARIALRGPPGPMGLTGRPGPVG-----GPGSSGAKGESGDPGPQGPRGV 566 Query: 657 --PPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKG------PMGPPGP 708 PPG G G +G G+ G +G PG G +G RG GLPG+ GDKG P GPPGP Sbjct: 567 QGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGP 626 Query: 709 KGDQG------EKGPRGLTGEPGMRGL------PGAVGEPGAKGAMGPAGPDGHQGPRGE 756 GD G E GPRGL GE G RGL PGA G+PG G GP GP G+ GP+GE Sbjct: 627 PGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE 686 Query: 757 QGLTGMPGIRGPPGPSGDPGKPGLTGP---QGPQGLPGTPGRPGIKGEPGAPGKIVTSEG 813 G PG +G PGP G PG G GP +GPQG PG G PG G PG PGK S Sbjct: 687 ---PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGE 743 Query: 814 SSMLTVPGPPGPPGAMGPPGPPGA------------------PGPAGPAGLPGHQEVLNL 855 L PGP GP G GP G GA PG G GL G + + Sbjct: 744 KGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 803 Query: 856 QGPPGPPGPRGPPGPSIP-GPPGPRGPPGE----GLPGPPGPPGSFLSNSETFLSGPPGP 910 GP G GP GP G + P G PGP G GE G+PG PG PG T G PG Sbjct: 804 IGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 863 Query: 911 ---------PGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGP 961 G PGP+G +GP GPRG +G +G G +S G GPPG GPQGP Sbjct: 864 NGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGP 923 Query: 962 K------GDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGP------------------ 997 + G KG PG PG G+P P + G + +GPPGP Sbjct: 924 QGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE 983 Query: 998 ---PGPPGPP---------GSISSSGQEIQQYISEYMQSDSIRSY-----LSGVQGPP-- 1038 PGPPGPP G + G Q IS +R + L G QG P Sbjct: 984 RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGL 1043 Query: 1039 ----GPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRD 1094 GP GPPGPV + GE S + + + R Sbjct: 1044 KGGEGPQGPPGPVGS-PGE-------------------------RGSAGTAGPIGLPGRP 1077 Query: 1095 DVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGIS--IGLPGPPG 1152 GP+GPPGP G G A G+ +GLPGP G Sbjct: 1078 -----------GPQGPPGPAGEKG---------APGEKGPQGPAGRDGVQGPVGLPGPAG 1117 Query: 1153 PPGLPGTSYEELLSLLRGSE-FRGIVGPPGPPGPPGIPGNVWS-----------SISVED 1200 P G PG ++ G + +G G GPPGPPG+ G V + + Sbjct: 1118 PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQG 1177 Query: 1201 LSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVR 1260 + G PGPPGP G G GPPG G EN D P Sbjct: 1178 MFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKG-------ENGD----------VGP--- 1217 Query: 1261 SFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGS 1320 +GPPGPPGP+GP G + D S S +G + G G Sbjct: 1218 ---MGPPGPPGPRGPQGPN---GADGPQGPPGSVGSVGGVGEKGEPGEAG---NPGPPGE 1268 Query: 1321 LGAGGAFGEAA--GDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAV 1378 G GG GE G+ GP G GP G G + G GN G +G F GD Sbjct: 1269 AGVGGPKGERGEKGEAGPPGA-AGPPGAKGPPGDDGP-KGNPGPVG--FPGD-------- 1316 Query: 1379 RVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQG 1438 GPPG+PGP G G+ G +G Sbjct: 1317 -------------------PGPPGEPGPAGQDGV---------------------GGDKG 1336 Query: 1439 PPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 G G+ G PGP G+ GP GPPG GPPG G +G +G+KG + AG Sbjct: 1337 EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAG 1384 Score = 434 bits (1117), Expect = e-121 Identities = 313/835 (37%), Positives = 355/835 (42%), Gaps = 227/835 (27%) Query: 567 GSPGPKG---DMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQR 623 G GPKG G PGP G G G G+PG G+PG QGPKG G G PG G G R Sbjct: 811 GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGAR 870 Query: 624 GREGPMGPRGEAGPPGS-GEKGERGAAGEPGPHG------PPGVPGSVGPKGSSGS---P 673 G G GPRG+ GP G G +G RG G+PGP G PPG PG GP+G G P Sbjct: 871 GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFP 930 Query: 674 GPQGPPGPVGLQGL---------------------------------------------- 687 GP+GPPGP G GL Sbjct: 931 GPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPP 990 Query: 688 --RGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPA 745 GE GLPG G +G G PGP+G G+ GP GL G PG RGLPGA G PG KG GP Sbjct: 991 GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQ 1050 Query: 746 GPDGHQGPRGEQ---------GLTGMPGIRGPPGPSGDPGKPGLTGPQGPQ--------- 787 GP G G GE+ GL G PG +GPPGP+G+ G PG GPQGP Sbjct: 1051 GPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV 1110 Query: 788 GLP------GTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPP------ 835 GLP G+PG G KGE G PG+ S+G GPPGPPG GP G P Sbjct: 1111 GLPGPAGPAGSPGEDGDKGEIGEPGQ-KGSKGDK--GENGPPGPPGLQGPVGAPGIAGGD 1167 Query: 836 GAPGPAGPAGL------------PGHQEVLNLQGPPGPPGPR------GPPGPSIPGPPG 877 G PGP G G+ PG + LQG PGPPG + GP GP PGPPG Sbjct: 1168 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP--PGPPG 1225 Query: 878 PRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGP---PGPPGPKGDQGPPGPRGHQGEQG 933 PRGP G G GP GPPGS S G PG PGPPG G GP G RG +GE G Sbjct: 1226 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG 1285 Query: 934 LPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGAL---------GIPSGPSEGG 984 PG + + GP G PGP G GD G PG PG G P + G Sbjct: 1286 PPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG 1345 Query: 985 SSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPP 1044 +GPPGPPG GPPG+ + G+ Q + +G +GPPG GP Sbjct: 1346 PPGPSGEAGPPGPPGKRGPPGAAGAEGR----------QGEKGAKGEAGAEGPPGKTGPV 1395 Query: 1045 GPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYL 1104 GP + G+ + + + +D Sbjct: 1396 GPQGPAG-----------------KPGPEGLRGIPGPVGEQGLPGAAGQDGP-------- 1430 Query: 1105 MGPRGPPGPPGASGD-GSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEE 1163 GP GPPG PG GD GS + L IGL GPPG G G Sbjct: 1431 PGPMGPPGLPGLKGDPGSKGEKGHPGL--------------IGLIGPPGEQGEKGD---- 1472 Query: 1164 LLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPP 1223 RG G G PG G GIPG AG PGPPG PGP Sbjct: 1473 -----RG--LPGTQGSPGAKGDGGIPG----------------PAGPLGPPGPPGLPGPQ 1509 Query: 1224 GPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGD 1278 GP+G G +G A + DS G PGPPG GPPG+ Sbjct: 1510 GPKGNKGSTGP----AGQKGDS-------------------GLPGPPGSPGPPGE 1541 Score = 420 bits (1080), Expect = e-117 Identities = 350/997 (35%), Positives = 411/997 (41%), Gaps = 221/997 (22%) Query: 590 PGIPGPL--------GHPGPQGPKGQKG--SVGDPGM--EGPMGQRGREGPMGPRGEAGP 637 PG+P GH G G KGQKG +V +PGM EGP G G G MGP G GP Sbjct: 403 PGVPAETDITETSINGH-GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGP 461 Query: 638 PGS-GEKGERGAAGEPGPHGPPGVPGSVGPK-------GSSGSPGP-------------- 675 G G+ G+RG G PG G G+PG G G GS GP Sbjct: 462 TGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQ 521 Query: 676 ------QGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGL 729 +GPPGP+GL G G VG PG G KG G PGP+G +G +GP G TG+PG RG Sbjct: 522 QARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGR 581 Query: 730 PGAVGE---PGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGP 786 PGA G PG GA G G DG G G++G G G +GPPGP GD G G G GP Sbjct: 582 PGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 641 Query: 787 QGLPGTPGRPGI---KGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGP---PGPPGAPGP 840 +GLPG G G+ +G PGAPG+ M V GPPGP G MGP PGPPG G Sbjct: 642 RGLPGEAGPRGLLGPRGTPGAPGQ------PGMAGVDGPPGPKGNMGPQGEPGPPGQQGN 695 Query: 841 AGPAGLPGHQEVLNLQGPPGPPGPRGPPG-PSIPGPPGPRGPPGEGLPGPPGPPGSFLSN 899 GP GLPG QGP GPPG +GP G P + G PG GPPG PG G G Sbjct: 696 PGPQGLPGP------QGPIGPPGEKGPQGKPGLAGLPGADGPPGH--PGKEGQSG----- 742 Query: 900 SETFLSGPPGPPGP---PGPKGDQGPPGPRG------HQGEQGLPGFSTSGSSSFGLNLQ 950 E GPPGP GP PGP+G +G G RG +GE G PGF GL Sbjct: 743 -EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK----GDMGLKGD 797 Query: 951 -------GPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGP 1003 GP G GP+GPKG G G PG PSG + G + V G PG PG GP Sbjct: 798 RGEVGQIGPRGEDGPEGPKGRAGPTGDPG----PSG--QAGEKGKLGVPGLPGYPGRQGP 851 Query: 1004 PGSIS------SSGQEIQQYISEYMQSDSIRSYLS--GVQGPPGPPGPPGPVTTITGETF 1055 GS ++G++ + ++ R G +G GP G PGP T G+ Sbjct: 852 KGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 911 Query: 1056 DYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPG 1115 G+ +D L Q G GPPGP G Sbjct: 912 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLP----GHPGQRGETGFQGKTGPPGPGG 967 Query: 1116 ASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPP---GLPGTSYEE--------- 1163 G + + R G PGPPGPP GLPG + +E Sbjct: 968 VVGPQGPTG-ETGPIGER------------GHPGPPGPPGEQGLPGAAGKEGAKGDPGPQ 1014 Query: 1164 -------------------LLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSY 1204 L +G GP GPPGP G PG S+ Sbjct: 1015 GISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA--------- 1065 Query: 1205 LHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIV 1264 TAG +PG PGP GPPGP G G G D + V Sbjct: 1066 -GTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP--------------V 1110 Query: 1265 GPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAG 1324 G PGP GP G PG+ ++GS + G G G Sbjct: 1111 GLPGPAGPAGSPGED------------GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPV 1158 Query: 1325 GAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESM 1384 GA G A GD P GP G G + G G G G G + L E Sbjct: 1159 GAPGIAGGDGEP-----GPRGQQGMFGQKG-DEGARGFPGP--PGPIGLQGLPGPPGEKG 1210 Query: 1385 QRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKG 1444 + + GPPG PGP+GP G + QGPPG G Sbjct: 1211 ENGDV------GPMGPPGPPGPRGPQGPNGA------------------DGPQGPPGSVG 1246 Query: 1445 EMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGD 1481 +G G KG+ G AG PG PG G G KGE+G+KG+ Sbjct: 1247 SVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGE 1283 Score = 395 bits (1014), Expect = e-109 Identities = 225/493 (45%), Positives = 251/493 (50%), Gaps = 41/493 (8%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGR 625 +G PGP G+ G+PG KG +G G G+ GP+G PGP GP G G GD G G GQ+G Sbjct: 1080 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGS 1139 Query: 626 EGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGL 684 +G G G GPPG G G G AG G GP G G G KG G+ G GPPGP+GL Sbjct: 1140 KGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL 1199 Query: 685 QGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVG------EPGA 738 QGL G G G GD GPMGPPGP G +G +GP G G G G G+VG EPG Sbjct: 1200 QGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGE 1259 Query: 739 KGAMGP---AGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGR 795 G GP AG G +G RGE+G G PG GPPG G PG G G GP G PG PG Sbjct: 1260 AGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1319 Query: 796 PGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNL 855 PG G G G PGPPGP G GPPGPPG GP G AG G Q Sbjct: 1320 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGA 1379 Query: 856 QGPPGPPGPRGPPGPSIPGPPGPRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPPGPP 914 +G G GP G GP GP GP G PG EGL G PGP G GPPGP GPP Sbjct: 1380 KGEAGAEGPPGKTGPV--GPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPP 1437 Query: 915 GPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGAL 974 G G +G PG +G +G GL G GPPG QG KGD+G +PG Sbjct: 1438 GLPGLKGDPGSKGEKGHPGLIGLI---------------GPPGEQGEKGDRG---LPGTQ 1479 Query: 975 GIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGV 1034 G P +GG GPPGPPG PGP G + G + + SG+ Sbjct: 1480 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGS----------TGPAGQKGDSGL 1529 Query: 1035 QGPPGPPGPPGPV 1047 GPPG PGPPG V Sbjct: 1530 PGPPGSPGPPGEV 1542 Score = 387 bits (995), Expect = e-107 Identities = 267/717 (37%), Positives = 314/717 (43%), Gaps = 176/717 (24%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPG---------PLGHPGPQGPKGQKGS---VGD 613 RGS G +G G PGPKG G G PG PG P+G PGP+GP G G G Sbjct: 888 RGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGH 947 Query: 614 PGMEGPMGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPG---VPGSVGPKGS 669 PG G G +G+ GP GP G GP G +GE G G G PGP GPPG +PG+ G +G+ Sbjct: 948 PGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGA 1007 Query: 670 SGSPGPQG---PPGPVGLQGLRGEVGLPG------VKGDKGPMGPPGPKGDQGEKG---- 716 G PGPQG GP GL+G GE GLPG +KG +GP GPPGP G GE+G Sbjct: 1008 KGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGT 1067 Query: 717 --PRGLTGEPGMRGLPGAVGE---PGAKGAMGPAGPDGHQGP------------------ 753 P GL G PG +G PG GE PG KG GPAG DG QGP Sbjct: 1068 AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGD 1127 Query: 754 ---------------RGEQGLTGMPGIRGP------------PGPSGDPGKPGLTGPQGP 786 +GE G G PG++GP PGP G G G G +G Sbjct: 1128 KGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA 1187 Query: 787 QGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVP-GPPGPPGAMGPPGPPGAPGPAGPAG 845 +G PG PG G++G PG PG+ +G + P GPPGPPG GP GP GA GP GP G Sbjct: 1188 RGFPGPPGPIGLQGLPGPPGE----KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPG 1243 Query: 846 LPGHQEVLNLQGPPGPPGPRGPPG-------------------PSIPGPPGPRGPPGE-- 884 G + +G PG G GPPG P GPPG +GPPG+ Sbjct: 1244 SVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDG 1303 Query: 885 --------GLPGPPGPPGSFLSNSETFLSGP------PGPPGPPGPKGDQGPPGP---RG 927 G PG PGPPG + + G PG PGPPGP G+ GPPGP RG Sbjct: 1304 PKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRG 1363 Query: 928 HQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSS 987 G G G + +GPPG GP GP+G G PG G GIP E G Sbjct: 1364 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1423 Query: 988 TMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPV 1047 GPPGP GPPG PG G + ++ G G G GPPG Sbjct: 1424 AAGQDGPPGPMGPPGLPGLKGDPGSKGEK----------------GHPGLIGLIGPPGE- 1466 Query: 1048 TTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGP 1107 GE D + + G G+ + + L GP Sbjct: 1467 ---QGEKGDRGLPGTQGSPGAKGDG-GIPGPAGPLGPPGPPG--------------LPGP 1508 Query: 1108 RGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEEL 1164 +GP G G++G G S GLPGPPG PG PG + L Sbjct: 1509 QGPKGNKGSTGPA------------------GQKGDS-GLPGPPGSPGPPGEVIQPL 1546 Score = 250 bits (638), Expect = 8e-66 Identities = 261/814 (32%), Positives = 298/814 (36%), Gaps = 179/814 (21%) Query: 768 PPGPSGDPGKPGLTG-PQGPQGLPGTPGRPGIKGEPGA--PGKIVTSEGSSMLTVPGPPG 824 PP PG P T + G G G KGEP PG +V GPPG Sbjct: 396 PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVE----------GPPG 445 Query: 825 PPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGP------ 878 P G G GPPG GP GP G PG +GPPG PG G G +PGPPG Sbjct: 446 PAGPAGIMGPPGLQGPTGPPGDPGD------RGPPGRPGLPGADG--LPGPPGTMLMLPF 497 Query: 879 ------------------------------RGPPG----EGLPGPPGPPGSFLSNSETFL 904 RGPPG G PGP G PGS + Sbjct: 498 RYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGS------SGA 551 Query: 905 SGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGF----------STSGSSSF-GL------ 947 G G PGP GP+G QGPPGP G G++G PG G F GL Sbjct: 552 KGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 611 Query: 948 -------NLQGPPGPPGPQ---------GPKGDKGDPGVPGALGIPSGPSEGGSSSTMYV 991 QGPPGPPG GP+G G+ G G LG P G V Sbjct: 612 KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 671 Query: 992 SGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGP----- 1046 GPPGP G GP G GQ Q + L G QGP GPPG GP Sbjct: 672 DGPPGPKGNMGPQGEPGPPGQ----------QGNPGPQGLPGPQGPIGPPGEKGPQGKPG 721 Query: 1047 VTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMG 1106 + + G S G I V D VR + G Sbjct: 722 LAGLPGADGPPGHPGKEGQSG-EKGALGPPGPQGPIGYPGPRGVKGADGVRGL--KGSKG 778 Query: 1107 PRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEE-LL 1165 +G G PG GD L D E+ G GP G PG G + E+ L Sbjct: 779 EKGEDGFPGFKGDMGLKG-DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 837 Query: 1166 SLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGP 1225 + + G GP G G PG PG + G++ PGP G GP GP Sbjct: 838 GVPGLPGYPGRQGPKGSTGFPGFPG----------ANGEKGARGVAGKPGPRGQRGPTGP 887 Query: 1226 ------RGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDS 1279 RGP G G T + E P VG PGP GP GPPG Sbjct: 888 RGSRGARGPTGKPGPKGTSGGDGPPGPPGE-----RGPQGPQGPVGFPGPKGPPGPPGKD 942 Query: 1280 RLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAA--GDRGPY 1337 L H +RG + + G G +G G GE G+RG Sbjct: 943 GL-------------PGHPG--QRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP 987 Query: 1338 GTDIGPG--GGYGAAAEGGMYAGNG--GLLGADFAGDLDYNELAVRVSESMQRQGLLQGM 1393 G PG G GAA + G G G+ G D L + + GL G Sbjct: 988 GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG- 1046 Query: 1394 AYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKG 1453 +GP G PGP G PG S TA + G QGPPG GE G PG KG Sbjct: 1047 ----EGPQGPPGPVGSPG-----ERGSAGTAGPIGLPGRPGP-QGPPGPAGEKGAPGEKG 1096 Query: 1454 DRGPA------GPPGHPGPPGPRGHKGEKGDKGD 1481 +GPA GP G PGP GP G GE GDKG+ Sbjct: 1097 PQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1130 Score = 248 bits (633), Expect = 3e-65 Identities = 138/278 (49%), Positives = 154/278 (55%), Gaps = 31/278 (11%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKG---QKGSVGDPGMEGPMGQR 623 G PG KG G GPKG+ G G PG PGP G PGP G G KG GDPG GP G Sbjct: 1291 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPS 1350 Query: 624 GREGPMGPRGEAGPPGS----GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGP- 678 G GP GP G+ GPPG+ G +GE+GA GE G GPPG G VGP+G +G PGP+G Sbjct: 1351 GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR 1410 Query: 679 --PGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEP 736 PGPVG QGL G G G G GP G PG KGD G KG +G PG+ GL G GE Sbjct: 1411 GIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKG---HPGLIGLIGPPGEQ 1467 Query: 737 GAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRP 796 G KG G G G G +G+ G I GP GP G PG PGL GPQGP+G G+ G Sbjct: 1468 GEKGDRGLPGTQGSPGAKGDGG------IPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA 1521 Query: 797 GIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGP 834 G KG+ G PG PG PGPPG + P P Sbjct: 1522 GQKGDSGLPGP------------PGSPGPPGEVIQPLP 1547 Score = 188 bits (478), Expect = 3e-47 Identities = 204/715 (28%), Positives = 247/715 (34%), Gaps = 193/715 (26%) Query: 878 PRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGD----------QGPPGPRG 927 P PP E PG P +ET ++G G G G KG+ +GPPGP G Sbjct: 393 PTSPPNEEFG--PGVPAE-TDITETSINGH-GAYGEKGQKGEPAVVEPGMLVEGPPGPAG 448 Query: 928 HQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSE----- 982 G G PG LQGP GPPG G +G G PG+PGA G+P P Sbjct: 449 PAGIMGPPG------------LQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 496 Query: 983 ---GGSSST-------------------MYVSGPPGP------PGPPGPPGSISSSGQEI 1014 GG S + + GPPGP PGP G PGS + G+ Sbjct: 497 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGES- 555 Query: 1015 QQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYG 1074 D GVQGPPGP G PG + G G Sbjct: 556 ---------GDPGPQGPRGVQGPPGPTGKPGKRGRPGAD-----------------GGRG 589 Query: 1075 VSLFSSSISSE--DILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSS 1132 + + D L L D + G RGP GPPG GD + D E+ Sbjct: 590 MPGEPGAKGDRGFDGLPGLPGDKGHR-------GERGPQGPPGPPGDDGMRGED-GEIGP 641 Query: 1133 RILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGP---------P 1183 R L + +G G PG PG PG + G+ GPPGP P Sbjct: 642 RGLPGEAGPRGLLGPRGTPGAPGQPGMA--------------GVDGPPGPKGNMGPQGEP 687 Query: 1184 GPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENS 1243 GPPG GN G +PGP GP GPPG +GP G G A+ Sbjct: 688 GPPGQQGN----------------PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGP 731 Query: 1244 DSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRR 1303 + +GPPGP GP G PG + D S Sbjct: 732 PGHPGK-----EGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFP 786 Query: 1304 GSSYSSSMSTGGGGAGSLGAGGAFGEAA--------GDRGPYGT-----DIGPGGGYGAA 1350 G + G G +G G G GD GP G +G G G Sbjct: 787 GFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYP 846 Query: 1351 AEGGMYAGNG--GLLGADFAGDLDYNELAVRVSESMQR--------------------QG 1388 G G G GA+ G+ +A + QR +G Sbjct: 847 GRQGPKGSTGFPGFPGAN--GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 904 Query: 1389 LLQGMA----------YTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTY----- 1433 G QGP G PGP+GPPG + FQ Sbjct: 905 TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 964 Query: 1434 -GAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGR 1487 G + GP G GE G G +G GP GPPG G PG G +G KGD G Q +G+ Sbjct: 965 PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1019 Score = 139 bits (349), Expect = 3e-32 Identities = 156/556 (28%), Positives = 189/556 (33%), Gaps = 147/556 (26%) Query: 957 GPQGPKGDKGDPGV--PGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEI 1014 G G KG KG+P V PG L + P G + M GPPG GP GPPG G Sbjct: 420 GAYGEKGQKGEPAVVEPGML-VEGPPGPAGPAGIM---GPPGLQGPTGPPGDPGDRGPP- 474 Query: 1015 QQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYG 1074 G G PG G PGP T+ F Y G Sbjct: 475 ------------------GRPGLPGADGLPGPPGTMLMLPFRYG---------------G 501 Query: 1075 VSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRI 1134 +IS+++ A + L+Q + RGPPGP Sbjct: 502 DGSKGPTISAQEAQA-------QAILQQARIALRGPPGP--------------------- 533 Query: 1135 LSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWS 1194 +GL G PGP G PG+S +G G PGP GP G+ G Sbjct: 534 ----------MGLTGRPGPVGGPGSSGA-----------KGESGDPGPQGPRGVQG---- 568 Query: 1195 SISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYL 1254 PPGP G PG RG PG G + R L Sbjct: 569 ---------------------PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG--FDGL 605 Query: 1255 TSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHS-RGSSSSSHSSSV-----RRGSSYS 1308 G GP GP GPPGD + D RG + + G+ Sbjct: 606 PGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQ 665 Query: 1309 SSMSTGGGGAGSLGAGGAFGEAA-----GDRGPYGTDIGPGGGYGAAAEGGMYA--GNGG 1361 M+ G G G G GE G+ GP G GP G G E G G G Sbjct: 666 PGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP-GPQGPIGPPGEKGPQGKPGLAG 724 Query: 1362 LLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSN 1421 L GAD E ++ G QGP G PGP+G G V + Sbjct: 725 LPGADGPPGHPGKEGQSGEKGALGPPG--------PQGPIGYPGPRGVKGADGVRGLKGS 776 Query: 1422 VTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGD 1481 D F PG KG+MG G +G+ G GP G GP GP+G G GD G Sbjct: 777 KGEKGEDGF---------PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 827 Query: 1482 QVYAGRRRRRSIAVKP 1497 AG + + + P Sbjct: 828 SGQAGEKGKLGVPGLP 843 Score = 105 bits (263), Expect = 3e-22 Identities = 62/131 (47%), Positives = 67/131 (51%), Gaps = 14/131 (10%) Query: 559 EQENGNLRGSPGPKGDMGS---PGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPG 615 EQ G GP G MG PG KGD G G G PG +G GP G +G+KG G PG Sbjct: 1418 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1477 Query: 616 MEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGP---KGSSGS 672 +G G +G G GP G GPP G G PGP GP G GS GP KG SG Sbjct: 1478 TQGSPGAKGDGGIPGPAGPLGPP--------GPPGLPGPQGPKGNKGSTGPAGQKGDSGL 1529 Query: 673 PGPQGPPGPVG 683 PGP G PGP G Sbjct: 1530 PGPPGSPGPPG 1540 Score = 33.9 bits (76), Expect = 1.2 Identities = 19/39 (48%), Positives = 22/39 (56%), Gaps = 9/39 (23%) Query: 566 RGSPGP---KGDMGSPGPKGDRGFPGTPGIPGPLGHPGP 601 +GS GP KGD G PGP PG+PG PG + P P Sbjct: 1515 KGSTGPAGQKGDSGLPGP------PGSPGPPGEVIQPLP 1547 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 493 bits (1269), Expect = e-139 Identities = 351/967 (36%), Positives = 427/967 (44%), Gaps = 135/967 (13%) Query: 565 LRGSPGPKGDMGSP----------GPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDP 614 L+G G KGD G GP G G PG PG PG LG PG +G KGQ G+ G Sbjct: 467 LQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPK 526 Query: 615 GMEGPMGQRGREGPMGPRGEAGP--PGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGS 672 G+ G G G G G +GE G G KG++G G PG G PG+PG+ G G G Sbjct: 527 GLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGL 586 Query: 673 PGPQGPPGPVGLQGLRG---EVGLPGVKGDKGPMGPPG--PKGDQGEKGPRGLTGEPGMR 727 PGP+G PG + +G RG GLPG+ G+ GPMGPPG P G GEKG +G+ G PG Sbjct: 587 PGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQP 646 Query: 728 GLPGAVGEPGAK-------GAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPG- 779 G+PG G+PG G G G DG G G+ GL G PG+ G PG G+PG PG Sbjct: 647 GIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI 706 Query: 780 -LTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPG-- 836 L GP GP+G PG PG PG G PG G + GPPGPPG GP G PG Sbjct: 707 GLPGPPGPKGFPGIPGPPGAPGTPGRIG------------LEGPPGPPGFPGPKGEPGFA 754 Query: 837 APGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS-IPGPPGPRGPPG-EGLPGPPGPPG 894 PGP GP GLPG + L +G G PGP GPPG + + G PGP+G G G PGP GPPG Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814 Query: 895 SFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPG 954 + GPPGPPG PGP G G G G +G+ G PG G +G PG Sbjct: 815 L----PGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGE----RGSPG 866 Query: 955 PPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEI 1014 PG GP G G PG+PG G P G+ M + GPPGPPGP G PG G + Sbjct: 867 IPGAPGPIGPPGSPGLPGKAGASGFP---GTKGEMGMMGPPGPPGPLGIPGRSGVPGLKG 923 Query: 1015 QQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPV-TTITGETFDYSELASHVVSYLRTSGY 1073 + G +G PG PGPPGP+ + G + E + Sbjct: 924 DDGLQGQPGLPGPTGE-KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI-------- 974 Query: 1074 GVSLFSSSISSEDILAVLQRDDVRQYL--RQYLMGPRGPPGPPGASGDGSLLSLDYAELS 1131 +S L D + L + L GP GP G PG G L+ + + Sbjct: 975 ------PGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT 1028 Query: 1132 SRILSYMSSSGIS-----IGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPP 1186 + + G+ G+PG PG PGLPG ++ + G+ GP G PG P Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1088 Query: 1187 GIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSF 1246 G PGN SV D PG PG PG PG +G PG+ G T Sbjct: 1089 GYPGNPGIKGSVGD-------------PGLPGLPGTPGAKGQPGLPGFPGT--------- 1126 Query: 1247 RSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSS 1306 GPPGP G GPPG+ L G +G Sbjct: 1127 -----------------PGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKP 1169 Query: 1307 YSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGM--YAGNGGLLG 1364 + G G G G G+ GP G G G +GG+ GN GL G Sbjct: 1170 GQDGIPGPAGQKGEPGQPG-----FGNPGPPGLP----GLSGQKGDGGLPGIPGNPGLPG 1220 Query: 1365 ADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTA 1424 G+ ++ G ++GP G PGPQGPPG Sbjct: 1221 P--KGEPGFHGF----PGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGP 1274 Query: 1425 DLMDFFQTYGAIQGP---PGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGD 1481 + G I+G PGQ G G PG KGD+GP G G+PG PG G KG+ G G Sbjct: 1275 EGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGV 1334 Query: 1482 QVYAGRR 1488 + G + Sbjct: 1335 PGFPGMK 1341 Score = 481 bits (1237), Expect = e-135 Identities = 366/1017 (35%), Positives = 439/1017 (43%), Gaps = 183/1017 (17%) Query: 568 SPGPKGDM-GSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGRE 626 SPG K D G G KG+RGFPG G PG G PGP+GP G +G GD G+ GP G +G Sbjct: 33 SPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIR 92 Query: 627 GPMGPRGEAGPPG-------------------SGEKGERGAAGEP------GPHGPPGVP 661 GP G G G PG +G KGERG G P GP GPPG+P Sbjct: 93 GPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP 152 Query: 662 GS------------VGPKGSSGSPGP---QGPPGPVGLQGLRGEVGLPGVKGDKGPMGPP 706 G GPKG+ G PGP QG PGP G+ G G G PG+ G GP G P Sbjct: 153 GMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLP 212 Query: 707 GPKGD--------QGEKGPRGLTGEPGM-------------------RGLPGAVGEPGAK 739 GPKG+ +GEKG +GL G PG +GLPG G PG Sbjct: 213 GPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPP 272 Query: 740 GAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIK 799 G GP GP G G +GE+G G PG RG PG G+ G+PG+ G G G PG PGR G K Sbjct: 273 GIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEK 330 Query: 800 GE------PGAPGKIVTSEGSSM-LTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEV 852 G+ PG PG ++ G+ + + G G PG G G G PG GP GLPG Sbjct: 331 GQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGA 390 Query: 853 LNLQGPPGPP---------GPRGPPGPSIPGPPGPRGPPG-EGLPGPPGPPGSFLSNSET 902 + GPPGPP G GPPG SIPGPPG G PG GLPGPPGP G + S+ Sbjct: 391 A-VMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449 Query: 903 FLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPK 962 PGPPGPPG GD+G G +G +G++G F + G + GPPG PG G Sbjct: 450 ICE--PGPPGPPGSPGDKGLQGEQGVKGDKGDTCF-----NCIGTGISGPPGQPGLPGL- 501 Query: 963 GDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYM 1022 PG PG+LG P E G + G PG PG PG PG S G+ M Sbjct: 502 -----PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGM 556 Query: 1023 QSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLR--TSGYGVSLFSS 1080 + D G G PG PG PG + G E R G+ Sbjct: 557 KGDKGELGSPGAPGLPGLPGTPGQ-DGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG 615 Query: 1081 SISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGD-GSLLSLDYAELSSRILSYMS 1139 +I V + Q + G G PG PG GD G ++ Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675 Query: 1140 SSGI--SIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSIS 1197 G+ GLPG PG PG+PG+ E G G+ GPPGP G PGIPG + + Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEP------GIPGIGLPGPPGPKGFPGIPGPPGAPGT 729 Query: 1198 VEDLSSYLHTAGLSFIPGPPGPPGP--------PGPRGPPGVSGALATYAAENSDSFRSE 1249 + GL PGPPG PGP PGP GPPG+ G + F Sbjct: 730 PGRI-------GLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGP 782 Query: 1250 LISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSS 1309 P R+ + G PGP G GP G + G + Sbjct: 783 -----PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI-------- 829 Query: 1310 SMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDI-GPGGGYGAAAEGGMYAGNGGLLGADFA 1368 G G G G GE GD GP G D+ GP G G+ G G +G + Sbjct: 830 -----PGPIGQPGLHGIPGE-KGDPGPPGLDVPGPPGERGSPG----IPGAPGPIGPPGS 879 Query: 1369 GDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMD 1428 L A + G++ GPPG PGP G PG S V Sbjct: 880 PGLPGKAGASGFPGTKGEMGMM--------GPPGPPGPLGIPGRSGV------------- 918 Query: 1429 FFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPR-----GHKGEKGDKG 1480 ++G G +G+ G PGP G++G G PG PGPPGP G KGEKG+ G Sbjct: 919 -----PGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG 970 Score = 479 bits (1233), Expect = e-135 Identities = 399/1176 (33%), Positives = 474/1176 (40%), Gaps = 303/1176 (25%) Query: 558 MEQENGNLRGS--PGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGP-------------- 601 M+ E G++ S PGPKG+ G PGP G +G PG GIPGP+G PGP Sbjct: 154 MKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPG 213 Query: 602 ---------QGPKGQKGSVGDPGMEGPMGQ----------------------RGREGPMG 630 QGPKG+KG G G GP GQ RG GP G Sbjct: 214 PKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273 Query: 631 PRGEAGPPGSGEKGERGAAGEPGPHGPPG------------------VPGSVGPKGSSGS 672 RG GPPG GEKGE+G GEPG G PG PG G G G Sbjct: 274 IRGPPGPPG-GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQ 332 Query: 673 PGPQGPPGPVGLQ----------GLRGEVGLPGVKGDKGP-------------------- 702 G GPPGP GL G +G +GLPG+ G+KG Sbjct: 333 KGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAV 392 Query: 703 MGPPGPKGDQGEKGPRGLTGEPGMR--GLPGAVGEPGAKGAMGPAGP------------- 747 MGPPGP G GE+G +G G PG+ G PG G+PGA G GP GP Sbjct: 393 MGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452 Query: 748 ---------------DGHQGPRGEQGLT----------------GMPGIRGPPGPSGDPG 776 G QG +G++G T G+PG+ GPPG G PG Sbjct: 453 PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512 Query: 777 KPG------LTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEG----SSMLTVPGPPGPP 826 + G TGP+G G+PG PG PG G G PG I+T G L PG PG P Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572 Query: 827 GAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPG---------PRGPPG-------- 869 G G PG G PG GP G PG +GPPG PG P GPPG Sbjct: 573 GLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632 Query: 870 ----------PSIPGPPGPRGPPGE--------GLPGPPGPPGSFLSNSETFLSGPPGPP 911 P PG PGP+G PG+ GLPG PG G + L G PG P Sbjct: 633 EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP 692 Query: 912 GPPGPKGDQGPPG-----PRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKG 966 G PG KG+ G PG P G +G G+PG + + + L+GPPGPPG GPKG+ G Sbjct: 693 GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG 752 Query: 967 D--PGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGP------PGPPGSISSSGQEIQQYI 1018 PG PG G+P G GPPGPPG PGP G + +GQ Sbjct: 753 FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGP--- 809 Query: 1019 SEYMQSDSIRSYLSGVQGPPGPPGPPGPVTT-----ITGETFDYSELASHVVSYLRTSGY 1073 M + GVQGPPGPPG PGP+ I GE D V G Sbjct: 810 ---MGPPGLPGI--GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864 Query: 1074 -GVSLFSSSISSEDILAVLQRDDVRQYL----RQYLMGPRGPPGP---PGASGDGSLLSL 1125 G+ I + + + +MGP GPPGP PG SG L Sbjct: 865 PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924 Query: 1126 DYAELSSRILSYMSSSGI--SIGLPGPPGP-----------------PGLPGTSYEELLS 1166 D + + G GLPGPPGP PG+PG S + Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984 Query: 1167 LLRG-------SEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGP 1219 L G S G+ GPPGP G PG+PG I L T G PGP G Sbjct: 985 GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQP-GLIGPPGLKG---TIGDMGFPGPQGV 1040 Query: 1220 PGPPGPRGPPGVSGA--LATYAAENSDSFRSEL-ISYLTSPDVRSFIVGPPGPPGPQGPP 1276 GPPGP G PG G+ L + D S + + L P + G PG PG +G Sbjct: 1041 EGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSV 1100 Query: 1277 GDSRLL----STDASHSRGSSSSSHSSSVRRGSSYSSSMSTGG--GGAGSLGAGGAFGEA 1330 GD L + A G + S G G G +G GG G+ Sbjct: 1101 GDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQP 1160 Query: 1331 A--GDRGPYGTD--IGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQR 1386 G++G G D GP G G + G GN G G + + Sbjct: 1161 GPPGEKGKPGQDGIPGPAGQKGEPGQPGF--GNPGPPG-------------LPGLSGQKG 1205 Query: 1387 QGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEM 1446 G L G + G PG PGP+G PG F + +QGPPG G Sbjct: 1206 DGGLPG----IPGNPGLPGPKGEPG------------------FHGFPGVQGPPGPPGSP 1243 Query: 1447 G--TPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKG 1480 G GPKG+ GP GPPG PGP G +G G +G G Sbjct: 1244 GPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPG 1279 Score = 467 bits (1201), Expect = e-131 Identities = 326/857 (38%), Positives = 390/857 (45%), Gaps = 181/857 (21%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPG---------------PLGHPGPQGPKGQ---- 607 G PG G G+ GPKGDRGFPG PG PG P G PGP GP G Sbjct: 760 GPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIG 819 Query: 608 -KGSVGDPGMEGPMGQRGREGPMGPRGEAGPPG------SGEKGERGAAGEPGPHGPPGV 660 +G G PG+ GP+GQ G G G +G+ GPPG GE+G G G PGP GPPG Sbjct: 820 VQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGS 879 Query: 661 PGSVGPKGSSGSPG---------PQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGD 711 PG G G+SG PG P GPPGP+G+ G G GL G G +G G PGP G+ Sbjct: 880 PGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE 939 Query: 712 QGEKGPRGLTGEPG-----MRGLPGAVGEPGAKGAMGPAGPDGHQ---GPRGEQGLTGMP 763 +G KG GL G PG + G G GEPG G G +GP G+Q G G+ GL+G P Sbjct: 940 KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQP 999 Query: 764 GIRGPPGPSGD---PGKPGLTGP------------QGPQGLPGTPGRPGIKGEPGAPG-- 806 G+ GPPGP G+ PG+PGL GP GPQG+ G PG G+ G+PG+PG Sbjct: 1000 GLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLP 1059 Query: 807 ---KIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPG 863 G S + +PG PGP G G PG PG PG G G PG L G PG PG Sbjct: 1060 GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPG------LPGLPGTPG 1113 Query: 864 PRGPPG----PSIPGPPGPR---GPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPG 915 +G PG P PGPPGP+ GPPG GLPG PGP G G PG PGPPG Sbjct: 1114 AKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGG---------GGHPGQPGPPG 1164 Query: 916 PK---GDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPG 972 K G G PGP G +GE G PGF GPPG PG G KGD G PG+PG Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGN----------PGPPGLPGLSGQKGDGGLPGIPG 1214 Query: 973 ALGIPSGPSEGGSSSTMYVSGPPGPPGPPGP--PGSISSSGQEIQQYISEYMQSDSIRSY 1030 G+P E G V GPPGPPG PGP G + G Q R Sbjct: 1215 NPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP----------QGPPGRPG 1264 Query: 1031 LSGVQGPPGPPGPPGPVTT--ITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDIL 1088 +G QG PGP GPPG I GE + + + L+ L + Sbjct: 1265 PTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNP------- 1317 Query: 1089 AVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLP 1148 R L G +G PG PG G + S + G GL Sbjct: 1318 -----------GRPGLNGMKGDPGLPGVPGFPGMKG------PSGVPGSAGPEG-EPGLI 1359 Query: 1149 GPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTA 1208 GPPGPPGLPG S + ++ +G GPPG PG PG+ G Sbjct: 1360 GPPGPPGLPGPSGQSII-------IKGDAGPPGIPGQPGLKG------------------ 1394 Query: 1209 GLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPG 1268 +PGP GP G PGP GPPG G + + + + P R + GPPG Sbjct: 1395 ----LPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGD-PGLPGQPGTRG-LDGPPG 1448 Query: 1269 PPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFG 1328 P G QGPPG G+SS +H + R S + + G + G + Sbjct: 1449 PDGLQGPPGPP-----------GTSSVAHGFLITRHSQTTDAPQCPQGTL-QVYEGFSLL 1496 Query: 1329 EAAGDRGPYGTDIGPGG 1345 G++ +G D+G G Sbjct: 1497 YVQGNKRAHGQDLGTAG 1513 Score = 463 bits (1191), Expect = e-130 Identities = 368/1009 (36%), Positives = 421/1009 (41%), Gaps = 179/1009 (17%) Query: 561 ENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPM 620 E G++ PG KGD G G G G PG PG PG G PG GPKG+ G + G GP Sbjct: 546 EPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPP 605 Query: 621 GQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGS-------- 672 G G G G G GPPG G G G G G G PG PG GPKG G Sbjct: 606 GNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKP 665 Query: 673 --PGPQGPPGPVGL---QGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMR 727 PG G G VGL GL G+ GLPG+ G KG G PG G GP G G PG+ Sbjct: 666 GLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPG----IGLPGPPGPKGFPGIP 721 Query: 728 GLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQ 787 G PGA G PG G GP GP G GP+GE G + GPPGP G PG G GP+G + Sbjct: 722 GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF----ALPGPPGPPGLPGFKGALGPKGDR 777 Query: 788 GLPGTPGRPGIKGEPGAPGK--IVTSEGSSMLTVPGPPGPP-----GAMGPPGPPGAPGP 840 G PG PG PG G G PG V G PGP GPP G GPPGPPG PGP Sbjct: 778 GFPGPPGPPGRTGLDGLPGPKGDVGPNGQ-----PGPMGPPGLPGIGVQGPPGPPGIPGP 832 Query: 841 AGPAGLPGHQEVLNLQGP-----PGPPGPRGPPGPSIPGPPGPRGPPGE-GLPGPPGPPG 894 G GL G GP PGPPG RG PG IPG PGP GPPG GLPG G G Sbjct: 833 IGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPG--IPGAPGPIGPPGSPGLPGKAGASG 890 Query: 895 SFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPG 954 + E + GPPGPPGP G G G PG +G G QG PG G PG Sbjct: 891 FPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950 Query: 955 PPGPQGP-----KGDKGDPGVPGA---------LGIPSGPSEGGSSSTMYVSGPPGP--- 997 PPGP P KG+KG+PG+PG G+P P + G S + GPPGP Sbjct: 951 PPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN 1010 Query: 998 PGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTT--ITGETF 1055 PG PG PG I G ++ I + GV+GPPGP G PG + + G+ Sbjct: 1011 PGLPGQPGLIGPPG--LKGTIGDMGFPGP-----QGVEGPPGPSGVPGQPGSPGLPGQKG 1063 Query: 1056 DYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPG 1115 D + +S + G L GP+G PG PG Sbjct: 1064 DKGDPG---ISSIGLPG-------------------------------LPGPKGEPGLPG 1089 Query: 1116 ASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEF-- 1173 G+ + S+G PG PG PG PG + L G+ Sbjct: 1090 YPGNPGIKG-------------------SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPP 1130 Query: 1174 --RGIVGPPGPPGPPGIPGNVWSS--ISVEDLSSYLHTAGLSFIPGP------PGPP--G 1221 +GI GPPG PG PG PG V G IPGP PG P G Sbjct: 1131 GPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFG 1190 Query: 1222 PPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSF--IVGPPGPPGPQGPPGDS 1279 PGP G PG+SG L P F + GPPGPPG GP Sbjct: 1191 NPGPPGLPGLSGQKGDGGLPGIPG-NPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP---- 1245 Query: 1280 RLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGT 1339 A + R G + + G G G GG GE G+ G G Sbjct: 1246 ------ALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGE-KGNPGQPGL 1298 Query: 1340 --------DIGPGGGYGAAAEGGM--YAGNGGLLGA-DFAGDLDYNELAVRVSESMQRQG 1388 D GP G G G+ G+ GL G F G M+ Sbjct: 1299 PGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG--------------MKGPS 1344 Query: 1389 LLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGT 1448 + G A +G PG GP GPPG+ + D I G PG KG G Sbjct: 1345 GVPGSA-GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGP-----PGIPGQPGLKGLPGP 1398 Query: 1449 PGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 GP+G GP GPPG PG G G G G KGD G+ R + P Sbjct: 1399 QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPP 1447 Score = 428 bits (1100), Expect = e-119 Identities = 299/757 (39%), Positives = 342/757 (45%), Gaps = 191/757 (25%) Query: 565 LRGSPGPKGDMGSPG-----PKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGP 619 L G PG KGD G PG P G+RG PG PG PGP+G PG G G+ G+ G PG +G Sbjct: 838 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGE 897 Query: 620 MGQRGREGPMGP------------------RGEAGPPG-SGEKGERGAAGEPGPHGP--P 658 MG G GP GP +G+ G PG +GEKG +G G PGP GP P Sbjct: 898 MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDP 957 Query: 659 GVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPR 718 + GS G KG G PG G GP G QGL G+ G PG+ G G GPPGPKG+ G G Sbjct: 958 NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQP 1017 Query: 719 GLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKP 778 GL G PG++G G +G PG +G GP GP G G G GL G G +G PG S G P Sbjct: 1018 GLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI-GLP 1076 Query: 779 GLTGPQGPQGLPGTPGRPGIKG---EPGAPGKIVT--SEGSSMLT----VPGPPGPPGAM 829 GL GP+G GLPG PG PGIKG +PG PG T ++G L PGPPGP G Sbjct: 1077 GLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS 1136 Query: 830 GPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS-IPGPPGPRGPPGE---G 885 GPPG PG PG GP G GH G PGPPG +G PG IPGP G +G PG+ G Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHP------GQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFG 1190 Query: 886 LPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGD---------QGPPGP----------- 925 PGPPG PG + L G PG PG PGPKG+ QGPPGP Sbjct: 1191 NPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGP 1250 Query: 926 RGHQGEQGLPGFSTSGSSSF-GL-NLQGPPGPPGPQGPKGDKGDPGVPGALGIPS----- 978 +G+ G QG PG G + F GL +GPPG PG G KG+KG+PG PG G+P Sbjct: 1251 KGNPGPQGPPG--RPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ 1308 Query: 979 GP----SEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGV 1034 GP G + G PG PG PG PG SG L G Sbjct: 1309 GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA-------GPEGEPGLIGP 1361 Query: 1035 QGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRD 1094 GPPG PGP G I G+ Sbjct: 1362 PGPPGLPGPSGQSIIIKGDA---------------------------------------- 1381 Query: 1095 DVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPP 1154 GP G PG PG GLPGP GP Sbjct: 1382 -----------GPPGIPGQPGLK----------------------------GLPGPQGPQ 1402 Query: 1155 GLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVED--LSSYLHTAGLSF 1212 GLPG + GPPG PG G+PG + D L T GL Sbjct: 1403 GLPGPT-----------------GPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLD- 1444 Query: 1213 IPGPPGPPGPPGPRGPPGVS----GALATYAAENSDS 1245 GPPGP G GP GPPG S G L T ++ +D+ Sbjct: 1445 --GPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDA 1479 Score = 367 bits (943), Expect = e-101 Identities = 234/531 (44%), Positives = 259/531 (48%), Gaps = 111/531 (20%) Query: 564 NLRGSPGPKGDMGSPG------PKGDRGFPGTPGIPGPLGHPG---PQGPKGQKGSVGDP 614 NL GS G KG+ G PG PKG +G PG PG PG G PG P GPKG G G P Sbjct: 958 NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQP 1017 Query: 615 GMEGPMGQRGR------------EGPMGPRGEAGPPGS----GEKGERG--------AAG 650 G+ GP G +G EGP GP G G PGS G+KG++G G Sbjct: 1018 GLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG 1077 Query: 651 EPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKG 710 PGP G PG+PG G G GS G G PG G G +G+ GLPG G GP PGPKG Sbjct: 1078 LPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGP---PGPKG 1134 Query: 711 DQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPG 770 G G GL GEPG G G G+PG G G G DG GP G++G G PG G PG Sbjct: 1135 ISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF-GNPG 1193 Query: 771 PSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMG 830 P PG PGL+G +G GLPG PG PG+ G G PG V GPPGPPG+ G Sbjct: 1194 P---PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGF------HGFPGVQGPPGPPGSPG 1244 Query: 831 PP--GPPGAPGPAGPAGLPGHQEVLNLQGPPGPPG---------PRGPPG----PSIPGP 875 P GP G PGP GP G PG L GP GPPG +G PG P +PG Sbjct: 1245 PALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1304 Query: 876 PGPRGPPG-------------------------EGLPGPPGPPGSFLSNSETFLSGPPGP 910 G +GPPG G+ GP G PGS E L GPPGP Sbjct: 1305 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1364 Query: 911 PGPPGP-------KGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKG 963 PG PGP KGD GPPG G G +GLPG QGP G PGP GP G Sbjct: 1365 PGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPG------------PQGPQGLPGPTGPPG 1412 Query: 964 DKGDPGVPG---ALGIPSGPSEGGSSSTMYVSGPPGPPG---PPGPPGSIS 1008 D G G+PG A G P G T + GPPGP G PPGPPG+ S Sbjct: 1413 DPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSS 1463 Score = 329 bits (844), Expect = 1e-89 Identities = 187/407 (45%), Positives = 221/407 (54%), Gaps = 50/407 (12%) Query: 562 NGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMG 621 N ++GS G G G PG G +G PG PG PG G PGP+G G G+ G PG GP+G Sbjct: 1093 NPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVG 1152 Query: 622 QRGREGPMGPRGEAGPPGS----GEKGERGAAGEP--GPHGPPGVPGSVGPKGSSGSPGP 675 G G GP GE G PG G G++G G+P G GPPG+PG G KG G PG Sbjct: 1153 GGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGI 1212 Query: 676 QGPPGPVGLQGLRGEVGLPGVKGDKGPMGPP-----GPKGDQGEKGPRGLTGEPGMRGLP 730 G PG G +G G G PGV+G GP G P GPKG+ G +GP G G G +GLP Sbjct: 1213 PGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLP 1272 Query: 731 GAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLP 790 G G PG G G G G+ G G GL G+ G +GPPG G+PG+PGL G +G GLP Sbjct: 1273 GPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLP 1332 Query: 791 GTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQ 850 G PG PG+KG G PG GP G PG +GPPGPPG PGP+G Sbjct: 1333 GVPGFPGMKGPSGVPGS------------AGPEGEPGLIGPPGPPGLPGPSG-------- 1372 Query: 851 EVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGP 910 + + ++G GPPG G PG + G PGP+GP +GLPGP GPPG + +G PG Sbjct: 1373 QSIIIKGDAGPPGIPGQPG--LKGLPGPQGP--QGLPGPTGPPG------DPGRNGLPGF 1422 Query: 911 PGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPG 957 G G KGD G PG G +G G PG LQGPPGPPG Sbjct: 1423 DGAGGRKGDPGLPGQPGTRGLDGPPGPD---------GLQGPPGPPG 1460 Score = 253 bits (645), Expect = 1e-66 Identities = 243/720 (33%), Positives = 273/720 (37%), Gaps = 184/720 (25%) Query: 827 GAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS-IPGPPGP---RGPP 882 G G G G PG G GLPG GP GPPGPRG G IPGPPGP RGPP Sbjct: 42 GIKGEKGERGFPGLEGHPGLPG------FPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPP 95 Query: 883 GEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGS 942 G LPG PG PG L G PG G PGP+G G G +G +G G PGF Sbjct: 96 G--LPGFPGTPG---------LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP---- 140 Query: 943 SSFGLNLQGPPGPPGPQGPKGD------------KGDPGVPGALGIPSGPSEGGSSSTMY 990 LQGPPGPPG G KG+ KG+PG PG GI P G + Sbjct: 141 -----GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIG 195 Query: 991 VSGPPG---PPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPV 1047 GPPG PPGPPG PG + G Q E G QG GPPGPPG + Sbjct: 196 PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGE-----------KGEQGLQGPPGPPGQI 244 Query: 1048 TTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGP 1107 S I Q+ D Q L G Sbjct: 245 ---------------------------------SEQKRPIDVEFQKGD------QGLPGD 265 Query: 1108 RGPPGPPGASGDGSLLSLDYAELSSR----------ILSYMSSSGISIGLPGPPGPPGLP 1157 RGPPGPPG G + E + GI GLPG PG PG P Sbjct: 266 RGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP-GLPGDPGYPGEP 324 Query: 1158 GTSYEELLSLLRGSEFRGIVGPPGPPGPPGI----PG-----NVWSSISVEDLSSYLHTA 1208 G E +G G GPPGPPG+ PG +I + L Sbjct: 325 GRDGE-----------KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGER 373 Query: 1209 GLSFIPGPPGPPGPP-----GPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFI 1263 G I GPPG PGPP GP GPPG G E L + Sbjct: 374 GFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGL 433 Query: 1264 VGP----------------PGPPGPQGPPGDSRLLSTD-ASHSRGSSSSSHSSSVRRGSS 1306 GP PGPPGP G PGD L +G + + + G Sbjct: 434 PGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPP 493 Query: 1307 YSSSMSTGGGGAGSLGAGGAFGE--AAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLG 1364 + G GSLG G GE AG GP G G G GA G G +L Sbjct: 494 GQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP-GIPGAPGAPGFPGSKGEPGDIL- 551 Query: 1365 ADFAG-DLDYNELAVRVSESMQRQGLLQGMAYT--VQGPPGQPGPQGPPGISKVFSAYSN 1421 F G D EL + L G+ T G PG PGP+G PG Sbjct: 552 -TFPGMKGDKGELGSPGAPG------LPGLPGTPGQDGLPGLPGPKGEPG---------- 594 Query: 1422 VTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGD 1481 T+ +GPPG G PG G+ GP GPPG GPPGP G KG +G G+ Sbjct: 595 --------GITFKGERGPPGNP---GLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGN 642 Score = 174 bits (442), Expect = 4e-43 Identities = 183/604 (30%), Positives = 212/604 (35%), Gaps = 194/604 (32%) Query: 912 GPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVP 971 G G KG++G PG GH G LPGF GP GPPGP+G KGD G PG P Sbjct: 42 GIKGEKGERGFPGLEGHPG---LPGFP------------GPEGPPGPRGQKGDDGIPGPP 86 Query: 972 GALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYL 1031 G GI GPPG PG PG PG G + Sbjct: 87 GPKGI---------------RGPPGLPGFPGTPGLPGMPGHD------------------ 113 Query: 1032 SGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVL 1091 G PGP G PG T F S G+ Sbjct: 114 ----GAPGPQGIPGCNGTKGERGFPGSP------------GF------------------ 139 Query: 1092 QRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPP 1151 L GP GPPG PG G E S I+S + + G PGPP Sbjct: 140 ----------PGLQGPPGPPGIPGMKG----------EPGSIIMSSLPGPKGNPGYPGPP 179 Query: 1152 GPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLS 1211 G GLPG + GI GP GPPGPPG+ G L GL+ Sbjct: 180 GIQGLPGPT--------------GIPGPIGPPGPPGLMGPP----GPPGLPGPKGNMGLN 221 Query: 1212 FIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPG 1271 F GP G G G +GPPG G + S+ R + + GPPGPPG Sbjct: 222 F-QGPKGEKGEQGLQGPPGPPGQI-------SEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273 Query: 1272 PQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAA 1331 +GPPG +RG + G G G G GE Sbjct: 274 IRGPPGPPG--------GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPG 325 Query: 1332 --GDRGPYGTDIGPGGGYGAAAEG---GMYAGNGGLLGADFAGDLDYNELAVRVSESMQR 1386 G++G G D GP G G G+ G G +G E R +Q Sbjct: 326 RDGEKGQKG-DTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLP----GEKGERGFPGIQG 380 Query: 1387 QGLLQGM-AYTVQGPPGQPG---------PQGPPGISKVFSAYSNVTADLMDFFQTYGAI 1436 L G V GPPG PG +GPPGIS I Sbjct: 381 PPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS----------------------I 418 Query: 1437 QGPPGQKGEMGTPGPKGDRGPAGP----------------PGHPGPPGPRGHKGEKGDKG 1480 GPPG G+ G PG G GPAGP PG PG G +G +G KGDKG Sbjct: 419 PGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKG 478 Query: 1481 DQVY 1484 D + Sbjct: 479 DTCF 482 Score = 133 bits (335), Expect = 1e-30 Identities = 81/179 (45%), Positives = 94/179 (52%), Gaps = 27/179 (15%) Query: 561 ENGN-----LRGSPGPKGDMGSPG------------PKGDRGFPGTP---GIPGPLGHPG 600 E GN L G PG KGD G PG KGD G PG P G+ GP G PG Sbjct: 1289 EKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPG 1348 Query: 601 PQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGV 660 GP+G+ G +G PG G G G+ + +G+AGPPG G+ G G PGP GP G+ Sbjct: 1349 SAGPEGEPGLIGPPGPPGLPGPSGQS--IIIKGDAGPPGI--PGQPGLKGLPGPQGPQGL 1404 Query: 661 PGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRG 719 PG GP G PG G PG G G +G+ GLPG G +G GPPGP G QG GP G Sbjct: 1405 PGPTGP---PGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460 Score = 59.7 bits (143), Expect = 2e-08 Identities = 37/91 (40%), Positives = 39/91 (42%), Gaps = 30/91 (32%) Query: 1399 GPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGE---MGTPGPKGDR 1455 G PG PGP+GPPG P GQKG+ G PGPKG R Sbjct: 60 GLPGFPGPEGPPG---------------------------PRGQKGDDGIPGPPGPKGIR 92 Query: 1456 GPAGPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 GP G PG PG PG G G G G Q G Sbjct: 93 GPPGLPGFPGTPGLPGMPGHDGAPGPQGIPG 123 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 492 bits (1267), Expect = e-138 Identities = 352/970 (36%), Positives = 426/970 (43%), Gaps = 200/970 (20%) Query: 565 LRGSPGPKGDMGSP----------GPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDP 614 L+G G KGD G GP G G PG PG PG LG PG +G KGQ G+ G Sbjct: 467 LQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPK 526 Query: 615 GMEGPMGQRGREGPMGPRGEAGP--PGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGS 672 G+ G G G G G +GE G G KG++G G PG G PG+PG+ G G G Sbjct: 527 GLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGL 586 Query: 673 PGPQGPPGPVGLQGLRG---EVGLPGVKGDKGPMGPPG--PKGDQGEKGPRGLTGEPGMR 727 PGP+G PG + +G RG GLPG+ G+ GPMGPPG P G GEKG +G+ G PG Sbjct: 587 PGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQP 646 Query: 728 GLPGAVGEPGAK-------GAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPG- 779 G+PG G+PG G G G DG G G+ GL G PG+ G PG G+PG PG Sbjct: 647 GIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI 706 Query: 780 -LTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPG-- 836 L GP GP+G PG PG PG G PG G + GPPGPPG GP G PG Sbjct: 707 GLPGPPGPKGFPGIPGPPGAPGTPGRIG------------LEGPPGPPGFPGPKGEPGFA 754 Query: 837 APGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS-IPGPPGPRGPPG-EGLPGPPGPPG 894 PGP GP GLPG + L +G G PGP GPPG + + G PGP+G G G PGP GPPG Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPG 814 Query: 895 SFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPG 954 + GPPGPPG PGP G G G G +G+ G PG G +G PG Sbjct: 815 L----PGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGE----RGSPG 866 Query: 955 PPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEI 1014 PG GP G G PG+PG G P G+ M + GPPGPPGP G PG G + Sbjct: 867 IPGAPGPIGPPGSPGLPGKAGASGFP---GTKGEMGMMGPPGPPGPLGIPGRSGVPGLKG 923 Query: 1015 QQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPV-TTITGETFDYSELASHVVSYLRTSGY 1073 + G +G PG PGPPGP+ + G + E + Sbjct: 924 DDGLQGQPGLPGPTGE-KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI-------- 974 Query: 1074 GVSLFSSSISSEDILAVLQRDDVRQYL--RQYLMGPRGPPGPPGASGDGSLLSLDYAELS 1131 +S L D + L + L GP GP G PG G L+ + + Sbjct: 975 ------PGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT 1028 Query: 1132 SRILSYMSSSGIS-----IGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPP 1186 + + G+ G+PG PG PGLPG ++ + G+ GP G PG P Sbjct: 1029 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1088 Query: 1187 GIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSF 1246 G PGN SV D PG PG PG PG +G PG+ G T Sbjct: 1089 GYPGNPGIKGSVGD-------------PGLPGLPGTPGAKGQPGLPGFPGT--------- 1126 Query: 1247 RSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSS 1306 GPPGP G GPPG+ L Sbjct: 1127 -----------------PGPPGPKGISGPPGNPGL------------------------- 1144 Query: 1307 YSSSMSTGGGGAGSLGAGGAFGEAA--GDRGPYGTD--IGPGGGYGAAAEGGMYAGNGGL 1362 G G +G GG G+ G++G G D GP G G + G GN G Sbjct: 1145 --------PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF--GNPGP 1194 Query: 1363 LGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNV 1422 G + + G L G + G PG PGP+G PG Sbjct: 1195 PG-------------LPGLSGQKGDGGLPG----IPGNPGLPGPKGEPG----------- 1226 Query: 1423 TADLMDFFQTYGAIQGPPGQKGEMG--TPGPKGDRGPAGPPGHP---------GPPGPRG 1471 F + +QGPPG G G GPKG+ GP GPPG P GPPG G Sbjct: 1227 -------FHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPG 1279 Query: 1472 HKGEKGDKGD 1481 + G KG+KG+ Sbjct: 1280 NGGIKGEKGN 1289 Score = 481 bits (1237), Expect = e-135 Identities = 366/1017 (35%), Positives = 439/1017 (43%), Gaps = 183/1017 (17%) Query: 568 SPGPKGDM-GSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGRE 626 SPG K D G G KG+RGFPG G PG G PGP+GP G +G GD G+ GP G +G Sbjct: 33 SPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIR 92 Query: 627 GPMGPRGEAGPPG-------------------SGEKGERGAAGEP------GPHGPPGVP 661 GP G G G PG +G KGERG G P GP GPPG+P Sbjct: 93 GPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP 152 Query: 662 GS------------VGPKGSSGSPGP---QGPPGPVGLQGLRGEVGLPGVKGDKGPMGPP 706 G GPKG+ G PGP QG PGP G+ G G G PG+ G GP G P Sbjct: 153 GMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLP 212 Query: 707 GPKGD--------QGEKGPRGLTGEPGM-------------------RGLPGAVGEPGAK 739 GPKG+ +GEKG +GL G PG +GLPG G PG Sbjct: 213 GPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPP 272 Query: 740 GAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIK 799 G GP GP G G +GE+G G PG RG PG G+ G+PG+ G G G PG PGR G K Sbjct: 273 GIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEK 330 Query: 800 GE------PGAPGKIVTSEGSSM-LTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEV 852 G+ PG PG ++ G+ + + G G PG G G G PG GP GLPG Sbjct: 331 GQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGA 390 Query: 853 LNLQGPPGPP---------GPRGPPGPSIPGPPGPRGPPG-EGLPGPPGPPGSFLSNSET 902 + GPPGPP G GPPG SIPGPPG G PG GLPGPPGP G + S+ Sbjct: 391 A-VMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449 Query: 903 FLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPK 962 PGPPGPPG GD+G G +G +G++G F + G + GPPG PG G Sbjct: 450 ICE--PGPPGPPGSPGDKGLQGEQGVKGDKGDTCF-----NCIGTGISGPPGQPGLPGL- 501 Query: 963 GDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYM 1022 PG PG+LG P E G + G PG PG PG PG S G+ M Sbjct: 502 -----PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGM 556 Query: 1023 QSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLR--TSGYGVSLFSS 1080 + D G G PG PG PG + G E R G+ Sbjct: 557 KGDKGELGSPGAPGLPGLPGTPGQ-DGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG 615 Query: 1081 SISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGD-GSLLSLDYAELSSRILSYMS 1139 +I V + Q + G G PG PG GD G ++ Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675 Query: 1140 SSGI--SIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSIS 1197 G+ GLPG PG PG+PG+ E G G+ GPPGP G PGIPG + + Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEP------GIPGIGLPGPPGPKGFPGIPGPPGAPGT 729 Query: 1198 VEDLSSYLHTAGLSFIPGPPGPPGP--------PGPRGPPGVSGALATYAAENSDSFRSE 1249 + GL PGPPG PGP PGP GPPG+ G + F Sbjct: 730 PGRI-------GLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGP 782 Query: 1250 LISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSS 1309 P R+ + G PGP G GP G + G + Sbjct: 783 -----PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI-------- 829 Query: 1310 SMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDI-GPGGGYGAAAEGGMYAGNGGLLGADFA 1368 G G G G GE GD GP G D+ GP G G+ G G +G + Sbjct: 830 -----PGPIGQPGLHGIPGE-KGDPGPPGLDVPGPPGERGSPG----IPGAPGPIGPPGS 879 Query: 1369 GDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMD 1428 L A + G++ GPPG PGP G PG S V Sbjct: 880 PGLPGKAGASGFPGTKGEMGMM--------GPPGPPGPLGIPGRSGV------------- 918 Query: 1429 FFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPR-----GHKGEKGDKG 1480 ++G G +G+ G PGP G++G G PG PGPPGP G KGEKG+ G Sbjct: 919 -----PGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG 970 Score = 467 bits (1201), Expect = e-131 Identities = 325/855 (38%), Positives = 389/855 (45%), Gaps = 180/855 (21%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPG---------------PLGHPGPQGPKGQ---- 607 G PG G G+ GPKGDRGFPG PG PG P G PGP GP G Sbjct: 760 GPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIG 819 Query: 608 -KGSVGDPGMEGPMGQRGREGPMGPRGEAGPPG------SGEKGERGAAGEPGPHGPPGV 660 +G G PG+ GP+GQ G G G +G+ GPPG GE+G G G PGP GPPG Sbjct: 820 VQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGS 879 Query: 661 PGSVGPKGSSGSPG---------PQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGD 711 PG G G+SG PG P GPPGP+G+ G G GL G G +G G PGP G+ Sbjct: 880 PGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGE 939 Query: 712 QGEKGPRGLTGEPG-----MRGLPGAVGEPGAKGAMGPAGPDGHQ---GPRGEQGLTGMP 763 +G KG GL G PG + G G GEPG G G +GP G+Q G G+ GL+G P Sbjct: 940 KGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQP 999 Query: 764 GIRGPPGPSGD---PGKPGLTGP------------QGPQGLPGTPGRPGIKGEPGAPG-- 806 G+ GPPGP G+ PG+PGL GP GPQG+ G PG G+ G+PG+PG Sbjct: 1000 GLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLP 1059 Query: 807 ---KIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPG 863 G S + +PG PGP G G PG PG PG G G PG L G PG PG Sbjct: 1060 GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPG------LPGLPGTPG 1113 Query: 864 PRGPPG----PSIPGPPGPR---GPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPG 915 +G PG P PGPPGP+ GPPG GLPG PGP G G PG PGPPG Sbjct: 1114 AKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGG---------GGHPGQPGPPG 1164 Query: 916 PK---GDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPG 972 K G G PGP G +GE G PGF GPPG PG G KGD G PG+PG Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGN----------PGPPGLPGLSGQKGDGGLPGIPG 1214 Query: 973 ALGIPSGPSEGGSSSTMYVSGPPGPPGPPGP--PGSISSSGQEIQQYISEYMQSDSIRSY 1030 G+P E G V GPPGPPG PGP G + G Q R Sbjct: 1215 NPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP----------QGPPGRPG 1264 Query: 1031 LSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAV 1090 G+ GP GPPG PG I GE + + + L+ L + Sbjct: 1265 FQGLPGPEGPPGLPGN-GGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNP--------- 1314 Query: 1091 LQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGP 1150 R L G +G PG PG G + S + G GL GP Sbjct: 1315 ---------GRPGLNGMKGDPGLPGVPGFPGMKG------PSGVPGSAGPEG-EPGLIGP 1358 Query: 1151 PGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGL 1210 PGPPGLPG S + ++ +G GPPG PG PG+ G Sbjct: 1359 PGPPGLPGPSGQSII-------IKGDAGPPGIPGQPGLKG-------------------- 1391 Query: 1211 SFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPP 1270 +PGP GP G PGP GPPG G + + + + P R + GPPGP Sbjct: 1392 --LPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGD-PGLPGQPGTRG-LDGPPGPD 1447 Query: 1271 GPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEA 1330 G QGPPG G+SS +H + R S + + G + G + Sbjct: 1448 GLQGPPGPP-----------GTSSVAHGFLITRHSQTTDAPQCPQGTL-QVYEGFSLLYV 1495 Query: 1331 AGDRGPYGTDIGPGG 1345 G++ +G D+G G Sbjct: 1496 QGNKRAHGQDLGTAG 1510 Score = 462 bits (1188), Expect = e-129 Identities = 366/1001 (36%), Positives = 417/1001 (41%), Gaps = 166/1001 (16%) Query: 561 ENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPM 620 E G++ PG KGD G G G G PG PG PG G PG GPKG+ G + G GP Sbjct: 546 EPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPP 605 Query: 621 GQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGS-------- 672 G G G G G GPPG G G G G G G PG PG GPKG G Sbjct: 606 GNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKP 665 Query: 673 --PGPQGPPGPVGL---QGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMR 727 PG G G VGL GL G+ GLPG+ G KG G PG G GP G G PG+ Sbjct: 666 GLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPG----IGLPGPPGPKGFPGIP 721 Query: 728 GLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQ 787 G PGA G PG G GP GP G GP+GE G + GPPGP G PG G GP+G + Sbjct: 722 GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF----ALPGPPGPPGLPGFKGALGPKGDR 777 Query: 788 GLPGTPGRPGIKGEPGAPGK--IVTSEGSSMLTVPGPPGPP-----GAMGPPGPPGAPGP 840 G PG PG PG G G PG V G PGP GPP G GPPGPPG PGP Sbjct: 778 GFPGPPGPPGRTGLDGLPGPKGDVGPNGQ-----PGPMGPPGLPGIGVQGPPGPPGIPGP 832 Query: 841 AGPAGLPGHQEVLNLQGP-----PGPPGPRGPPGPSIPGPPGPRGPPGE-GLPGPPGPPG 894 G GL G GP PGPPG RG PG IPG PGP GPPG GLPG G G Sbjct: 833 IGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPG--IPGAPGPIGPPGSPGLPGKAGASG 890 Query: 895 SFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPG 954 + E + GPPGPPGP G G G PG +G G QG PG G PG Sbjct: 891 FPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950 Query: 955 PPGPQGP-----KGDKGDPGVPGA---------LGIPSGPSEGGSSSTMYVSGPPGP--- 997 PPGP P KG+KG+PG+PG G+P P + G S + GPPGP Sbjct: 951 PPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN 1010 Query: 998 PGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTT--ITGETF 1055 PG PG PG I G ++ I + GV+GPPGP G PG + + G+ Sbjct: 1011 PGLPGQPGLIGPPG--LKGTIGDMGFPGP-----QGVEGPPGPSGVPGQPGSPGLPGQKG 1063 Query: 1056 DYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPG 1115 D + +S + G L GP+G PG PG Sbjct: 1064 DKGDPG---ISSIGLPG-------------------------------LPGPKGEPGLPG 1089 Query: 1116 ASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEF-- 1173 G+ + S+G PG PG PG PG + L G+ Sbjct: 1090 YPGNPGIKG-------------------SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPP 1130 Query: 1174 --RGIVGPPGPPGPPGIPGNVWSS--ISVEDLSSYLHTAGLSFIPGP------PGPP--G 1221 +GI GPPG PG PG PG V G IPGP PG P G Sbjct: 1131 GPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFG 1190 Query: 1222 PPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSF--IVGPPGPPGPQGP--PG 1277 PGP G PG+SG L P F + GPPGPPG GP G Sbjct: 1191 NPGPPGLPGLSGQKGDGGLPGIPG-NPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEG 1249 Query: 1278 DSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPY 1337 R G + + G G G G G GD+GP Sbjct: 1250 PKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG-LKGDQGPP 1308 Query: 1338 GTDIGPGGGYGAAAEGGMYAGNGGLLGA-DFAGDLDYNELAVRVSESMQRQGLLQGMAYT 1396 G G G GM G+ GL G F G M+ + G A Sbjct: 1309 GLQ----GNPGRPGLNGM-KGDPGLPGVPGFPG--------------MKGPSGVPGSA-G 1348 Query: 1397 VQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRG 1456 +G PG GP GPPG+ + D I G PG KG G GP+G G Sbjct: 1349 PEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGP-----PGIPGQPGLKGLPGPQGPQGLPG 1403 Query: 1457 PAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 P GPPG PG G G G G KGD G+ R + P Sbjct: 1404 PTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPP 1444 Score = 436 bits (1121), Expect = e-122 Identities = 294/711 (41%), Positives = 342/711 (48%), Gaps = 119/711 (16%) Query: 559 EQENGNLRGSPGPKGDMGS---PGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPG 615 E+ + + G+PGP G GS PG G GFPGT G G +G PGP GP G G G PG Sbjct: 861 ERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPG 920 Query: 616 MEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGP--PGVPGSVGPKGSSGSP 673 ++G G +G+ G GP +GEKG +G G PGP GP P + GS G KG G P Sbjct: 921 LKGDDGLQGQPGLPGP--------TGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLP 972 Query: 674 GPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAV 733 G G GP G QGL G+ G PG+ G G GPPGPKG+ G G GL G PG++G G + Sbjct: 973 GIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDM 1032 Query: 734 GEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTP 793 G PG +G GP GP G G G GL G G +G PG S G PGL GP+G GLPG P Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGIS-SIGLPGLPGPKGEPGLPGYP 1091 Query: 794 GRPGIK---GEPGAPGKIVT--SEGSSMLT----VPGPPGPPGAMGPPGPPGAPGPAGPA 844 G PGIK G+PG PG T ++G L PGPPGP G GPPG PG PG GP Sbjct: 1092 GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPV 1151 Query: 845 GLPGHQEVLNLQGPPGPPGPRGPPG-PSIPGPPGPRGPPGE---GLPGPPGPPGSFLSNS 900 G GH G PGPPG +G PG IPGP G +G PG+ G PGPPG PG Sbjct: 1152 GGGGH------PGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKG 1205 Query: 901 ETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQG 960 + L G PG PG PGPKG+ G G G QG G PG S G L+GP G PGPQG Sbjct: 1206 DGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG-------SPGPALEGPKGNPGPQG 1258 Query: 961 PKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISE 1020 P G G G+PG G P P GG G PG PG PG PG G Sbjct: 1259 PPGRPGFQGLPGPEGPPGLPGNGGIKGE---KGNPGQPGLPGLPGLKGDQG-------PP 1308 Query: 1021 YMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSS 1080 +Q + R L+G++G PG PG PG F + S V G Sbjct: 1309 GLQGNPGRPGLNGMKGDPGLPGVPG---------FPGMKGPSGVPGSAGPEG-------- 1351 Query: 1081 SISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSS 1140 L+GP GPPG PG SG ++ D Sbjct: 1352 --------------------EPGLIGPPGPPGLPGPSGQSIIIKGDAGP-----PGIPGQ 1386 Query: 1141 SGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVED 1200 G+ GLPGP GP GLPG + GPPG PG G+PG + D Sbjct: 1387 PGLK-GLPGPQGPQGLPGPT-----------------GPPGDPGRNGLPGFDGAGGRKGD 1428 Query: 1201 --LSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVS----GALATYAAENSDS 1245 L T GL GPPGP G GP GPPG S G L T ++ +D+ Sbjct: 1429 PGLPGQPGTRGLD---GPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDA 1476 Score = 253 bits (645), Expect = 1e-66 Identities = 243/720 (33%), Positives = 273/720 (37%), Gaps = 184/720 (25%) Query: 827 GAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS-IPGPPGP---RGPP 882 G G G G PG G GLPG GP GPPGPRG G IPGPPGP RGPP Sbjct: 42 GIKGEKGERGFPGLEGHPGLPG------FPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPP 95 Query: 883 GEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGS 942 G LPG PG PG L G PG G PGP+G G G +G +G G PGF Sbjct: 96 G--LPGFPGTPG---------LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP---- 140 Query: 943 SSFGLNLQGPPGPPGPQGPKGD------------KGDPGVPGALGIPSGPSEGGSSSTMY 990 LQGPPGPPG G KG+ KG+PG PG GI P G + Sbjct: 141 -----GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIG 195 Query: 991 VSGPPG---PPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPV 1047 GPPG PPGPPG PG + G Q E G QG GPPGPPG + Sbjct: 196 PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGE-----------KGEQGLQGPPGPPGQI 244 Query: 1048 TTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGP 1107 S I Q+ D Q L G Sbjct: 245 ---------------------------------SEQKRPIDVEFQKGD------QGLPGD 265 Query: 1108 RGPPGPPGASGDGSLLSLDYAELSSR----------ILSYMSSSGISIGLPGPPGPPGLP 1157 RGPPGPPG G + E + GI GLPG PG PG P Sbjct: 266 RGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP-GLPGDPGYPGEP 324 Query: 1158 GTSYEELLSLLRGSEFRGIVGPPGPPGPPGI----PG-----NVWSSISVEDLSSYLHTA 1208 G E +G G GPPGPPG+ PG +I + L Sbjct: 325 GRDGE-----------KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGER 373 Query: 1209 GLSFIPGPPGPPGPP-----GPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFI 1263 G I GPPG PGPP GP GPPG G E L + Sbjct: 374 GFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGL 433 Query: 1264 VGP----------------PGPPGPQGPPGDSRLLSTD-ASHSRGSSSSSHSSSVRRGSS 1306 GP PGPPGP G PGD L +G + + + G Sbjct: 434 PGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPP 493 Query: 1307 YSSSMSTGGGGAGSLGAGGAFGE--AAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLG 1364 + G GSLG G GE AG GP G G G GA G G +L Sbjct: 494 GQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP-GIPGAPGAPGFPGSKGEPGDIL- 551 Query: 1365 ADFAG-DLDYNELAVRVSESMQRQGLLQGMAYT--VQGPPGQPGPQGPPGISKVFSAYSN 1421 F G D EL + L G+ T G PG PGP+G PG Sbjct: 552 -TFPGMKGDKGELGSPGAPG------LPGLPGTPGQDGLPGLPGPKGEPG---------- 594 Query: 1422 VTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGD 1481 T+ +GPPG G PG G+ GP GPPG GPPGP G KG +G G+ Sbjct: 595 --------GITFKGERGPPGNP---GLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGN 642 Score = 174 bits (442), Expect = 4e-43 Identities = 183/604 (30%), Positives = 212/604 (35%), Gaps = 194/604 (32%) Query: 912 GPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVP 971 G G KG++G PG GH G LPGF GP GPPGP+G KGD G PG P Sbjct: 42 GIKGEKGERGFPGLEGHPG---LPGFP------------GPEGPPGPRGQKGDDGIPGPP 86 Query: 972 GALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYL 1031 G GI GPPG PG PG PG G + Sbjct: 87 GPKGI---------------RGPPGLPGFPGTPGLPGMPGHD------------------ 113 Query: 1032 SGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVL 1091 G PGP G PG T F S G+ Sbjct: 114 ----GAPGPQGIPGCNGTKGERGFPGSP------------GF------------------ 139 Query: 1092 QRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPP 1151 L GP GPPG PG G E S I+S + + G PGPP Sbjct: 140 ----------PGLQGPPGPPGIPGMKG----------EPGSIIMSSLPGPKGNPGYPGPP 179 Query: 1152 GPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLS 1211 G GLPG + GI GP GPPGPPG+ G L GL+ Sbjct: 180 GIQGLPGPT--------------GIPGPIGPPGPPGLMGPP----GPPGLPGPKGNMGLN 221 Query: 1212 FIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPG 1271 F GP G G G +GPPG G + S+ R + + GPPGPPG Sbjct: 222 F-QGPKGEKGEQGLQGPPGPPGQI-------SEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273 Query: 1272 PQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAA 1331 +GPPG +RG + G G G G GE Sbjct: 274 IRGPPGPPG--------GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPG 325 Query: 1332 --GDRGPYGTDIGPGGGYGAAAEG---GMYAGNGGLLGADFAGDLDYNELAVRVSESMQR 1386 G++G G D GP G G G+ G G +G E R +Q Sbjct: 326 RDGEKGQKG-DTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLP----GEKGERGFPGIQG 380 Query: 1387 QGLLQGM-AYTVQGPPGQPG---------PQGPPGISKVFSAYSNVTADLMDFFQTYGAI 1436 L G V GPPG PG +GPPGIS I Sbjct: 381 PPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS----------------------I 418 Query: 1437 QGPPGQKGEMGTPGPKGDRGPAGP----------------PGHPGPPGPRGHKGEKGDKG 1480 GPPG G+ G PG G GPAGP PG PG G +G +G KGDKG Sbjct: 419 PGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKG 478 Query: 1481 DQVY 1484 D + Sbjct: 479 DTCF 482 Score = 59.7 bits (143), Expect = 2e-08 Identities = 36/103 (34%), Positives = 43/103 (41%), Gaps = 42/103 (40%) Query: 1399 GPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPA 1458 G PG PGP+GPPG P GQKG+ G PGP G +G Sbjct: 60 GLPGFPGPEGPPG---------------------------PRGQKGDDGIPGPPGPKGIR 92 Query: 1459 GPPG---------------HPGPPGPRGHKGEKGDKGDQVYAG 1486 GPPG H G PGP+G G G KG++ + G Sbjct: 93 GPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPG 135 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 488 bits (1255), Expect = e-137 Identities = 377/1030 (36%), Positives = 446/1030 (43%), Gaps = 178/1030 (17%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGH------------PGPQGPKGQKGSVGDP 614 G+ G +G G PG KGDRGF G PG+PG GH PG G +G G +G Sbjct: 455 GADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPR 514 Query: 615 GMEGPMGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSP 673 G+ G G RG GP GP G GPPG G G +G G GP G PG PG G G+ G P Sbjct: 515 GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP 574 Query: 674 GPQGPPGPVGLQGLRGEVGLPGVKGDKGPMG------PPGPKGDQGEKGPRGLTGEPGMR 727 GPQG GP G +G +G+ GLPG+ G GP G PPG KG+QG GP+G G PG R Sbjct: 575 GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 634 Query: 728 GLPGAVGEPGAKGAMGPAGPDGHQG------PRGEQGLTGMPGIRGPPGP---------S 772 G+ G G G KG G G DG G +G++G G+PG RG GP + Sbjct: 635 GVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPT 694 Query: 773 GDPGKPGLTGPQGP---QGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAM 829 GDPG PGL G +G GLPG PGR G KG G PG S + G GP G Sbjct: 695 GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER 754 Query: 830 GPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS----IPGPPGPRGPPG-E 884 GP GP G GP G G G + GP GPPG RG PGP PGP GP GPPG + Sbjct: 755 GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKD 814 Query: 885 GLPGPPGPPGSFLSNSETFLSGPPGPPGPPG------PKGDQGPPGPRGHQGEQGLPGFS 938 GLPG PG G +T GPPG GP G P G++G PGP G GEQGLPG Sbjct: 815 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPG-- 872 Query: 939 TSGSSSFGLNLQGPPGPPGPQGPKGDKGDPG---VPGALGIPS---------------GP 980 T+G + GPPG PG GP G +G PG +PG G P P Sbjct: 873 TAGKEGTKGD-PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 931 Query: 981 SEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGP 1040 E G++ + GPPG PGP GPPG+ G ++ D GVQGP G Sbjct: 932 GERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD-------GVQGPVGL 984 Query: 1041 PGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYL 1100 PGP GP + GE D E+ T G Sbjct: 985 PGPAGP-PGVAGEDGDKGEVGDP--GQKGTKG---------------------------- 1013 Query: 1101 RQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGI--SIGLPGPPGP---PG 1155 + GP GPPGP G G D + + + G + G GPPGP G Sbjct: 1014 NKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQG 1073 Query: 1156 LPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPG 1215 LPG S E +G G VGP GPPGPPG G AG + G Sbjct: 1074 LPGPSGE------KGET--GDVGPMGPPGPPGPRG----------------PAGPNGADG 1109 Query: 1216 PPGPPG------PPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGP 1269 P GPPG PPG +G PG SG+ R E S G PGP Sbjct: 1110 PQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE-----RGEKGESGQPGEPGP 1164 Query: 1270 PGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGE 1329 PGP+GP GD RG + G G G+ G GE Sbjct: 1165 PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE 1224 Query: 1330 AA-----GDRGPYGTDIGPG--GGYGAAAEGGMYAGNG--GLLG-ADFAGDLDYNELAVR 1379 G RGP G+ G GG GA + G G G +G A AG + L Sbjct: 1225 NGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR-G 1283 Query: 1380 VSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGP 1439 + S+ +QG + A GPPG GP G PG+ A + G I GP Sbjct: 1284 LPGSVGQQG--RPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGL-----IGLI-GP 1335 Query: 1440 PGQKGE---------MGTPGPKGDRG---PAGPPGHPGPPGPRGHKGEKGDKGDQVYAGR 1487 PG++GE G+PG KG+ G +GP G GPPG G G KG KG G Sbjct: 1336 PGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGP 1395 Query: 1488 RRRRSIAVKP 1497 + + + P Sbjct: 1396 KGEKGVQGPP 1405 Score = 482 bits (1241), Expect = e-135 Identities = 390/1091 (35%), Positives = 457/1091 (41%), Gaps = 244/1091 (22%) Query: 557 MMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGM 616 +++Q LRG PGP G G PGP G PG+PG+ G G GPQGP+G +G G PG Sbjct: 391 ILQQARLALRGPPGPMGYTGRPGPLGQ---PGSPGLKGESGDLGPQGPRGPQGLTGPPGK 447 Query: 617 EGPMGQRGREGPMGPRGEAGPPGS----------GEKGERG---AAGEPGPHG------- 656 G G+ G +G G G+ G G GEKG RG A G PGP G Sbjct: 448 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD 507 Query: 657 -----PPGVPGSVGPKGSSGSPGPQGPPGPVGLQGL------------RGEVGLPGVKGD 699 P G+PG GP+G G GP G PGP G++G+ +GE G PG +G Sbjct: 508 DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 567 Query: 700 KGPMGPPGPK---GDQGEKGPRGLTGEPGMRGL------PGAVGEPGAKGAMGPAGPD-- 748 G G PGP+ G GEKGP+G G PGM G PG G PG KG GP+GP Sbjct: 568 PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGP 627 Query: 749 -------------------GHQGPRGEQGL---------------TGMPGIRGPPG---- 770 GH+G +GE G G+PG RG G Sbjct: 628 LGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGP 687 Query: 771 -----PSGDPGKPGLTGPQGP---QGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGP 822 P+GDPG PGL G +G GLPG PGR G KG G PG S + G Sbjct: 688 KGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGK 747 Query: 823 PGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGP----SIPGPPGP 878 GP G GP GP G GP G G G + GP GPPG RG PGP PGP GP Sbjct: 748 SGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP 807 Query: 879 RGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPP---------GPPGPKGDQGPPGPRGH 928 GPPG +GLPG PG G +T GPPGPP G GP G++G PGP G Sbjct: 808 PGPPGKDGLPGHPGQRGEVGFQGKT---GPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 864 Query: 929 QGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDP---GVPGALGIP-------- 977 GEQGLPG T+G + GPPG PG GP G +G P G+PG G P Sbjct: 865 PGEQGLPG--TAGKEGTKGD-PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGP 921 Query: 978 -------SGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSY 1030 P E G++ + GPPG PGP GPPG+ G ++ D Sbjct: 922 SGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD----- 976 Query: 1031 LSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAV 1090 GVQGP G PGP GP + GE D E+ T G Sbjct: 977 --GVQGPVGLPGPAGP-PGVAGEDGDKGEVGD--PGQKGTKG------------------ 1013 Query: 1091 LQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGI--SIGLP 1148 + GP GPPGP G G D + + + G + G Sbjct: 1014 ----------NKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1063 Query: 1149 GPPGP---PGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYL 1205 GPPGP GLPG S E +G G VGP GPPGPPG G Sbjct: 1064 GPPGPIGLQGLPGPSGE------KGE--TGDVGPMGPPGPPGPRG--------------- 1100 Query: 1206 HTAGLSFIPGPPGPP------GPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDV 1259 AG + GP GPP GPPG +G PG SG+ R E Sbjct: 1101 -PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE-----RGEKG 1154 Query: 1260 RSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAG 1319 S G PGPPGP+GP GD RG + G G Sbjct: 1155 ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1214 Query: 1320 SLGAGGAFGE-----AAGDRGPYGTDIGPG--GGYGAAAEGGMYA--GNGGLLG-ADFAG 1369 G+ G GE G RGP G+ G GG GA + G G G +G A AG Sbjct: 1215 QPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAG 1274 Query: 1370 DLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNV-TADLMD 1428 + L + S+ +QG + A GPPG GP G PG+ A L+ Sbjct: 1275 KPGPDGLR-GLPGSVGQQG--RPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIG 1331 Query: 1429 FFQTYG-----------AIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHK---- 1473 G QG PGQKGEMG PG G GP GPPG PGP GP+G K Sbjct: 1332 LIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATG 1391 Query: 1474 --GEKGDKGDQ 1482 G KG+KG Q Sbjct: 1392 PGGPKGEKGVQ 1402 Score = 441 bits (1133), Expect = e-123 Identities = 364/1063 (34%), Positives = 426/1063 (40%), Gaps = 243/1063 (22%) Query: 558 MEQENGNLRGSPGPKGDM----------GSPGPKGDRGFPGTPGI---PGPLGHPGPQGP 604 +E+ RG G KG+ G PGP+G G G PGI PGP+G PG +GP Sbjct: 285 LEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP 344 Query: 605 KGQKGSVGDPGMEGPMGQR-----------GREGPMGPRGEAGPPGSGEKGERGAAGEPG 653 G+ G G G GP G G +GP+ EA ++ G PG Sbjct: 345 PGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPG 404 Query: 654 PHGPP------GVPGSVGPKGSSGSPGPQGPPGPVGL---------------QGLRGEVG 692 P G G PGS G KG SG GPQGP GP GL G RG G Sbjct: 405 PMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPG 464 Query: 693 LPGVKGDK------------------------GPMGPPGPKGDQGEKGPRGLTGEPGMRG 728 PGVKGD+ GP G G +GD GE GPRGL GE G RG Sbjct: 465 DPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRG 524 Query: 729 LPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQ---- 784 L G G PG G G G DG QGP+G G G P GPPG G PG GL GPQ Sbjct: 525 LLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEP---GPPGQQGTPGTQGLPGPQGAIG 581 Query: 785 -----GPQGLPGTPGRPGIKGEPGAPGKIVTSEG-SSMLTVPGPPGPPGAMGPPGPPGAP 838 GPQG PG PG PG G PG PGK EG GP GP G +G PGP G Sbjct: 582 PHGEKGPQGKPGLPGMPGSDGPPGHPGK----EGPPGTKGNQGPSGPQGPLGYPGPRGVK 637 Query: 839 GPAGPAGLPGHQ------------------------EVLNLQGPPGPPGPRGPPGPS-IP 873 G G GL GH+ V +G GP GP+G GP+ P Sbjct: 638 GVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDP 697 Query: 874 GPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPGP---------PGPPGPKGDQGPP 923 GPPG G G+ G+PG PG PG G PG G GP+G++GP Sbjct: 698 GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 757 Query: 924 GPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGP---PGPQGPK---GDKGDPGVPGALGIP 977 GPRG +G +G G S + +S G GPPG PGPQGP G KG PG PG G+P Sbjct: 758 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 817 Query: 978 SGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGP 1037 P + G +GPPGPPG GP G+ +G G +G Sbjct: 818 GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP-------------------MGERGH 858 Query: 1038 PGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVR 1097 PGPPGPPG + G +D A L+ Sbjct: 859 PGPPGPPG---------------EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 903 Query: 1098 QYLRQYLMGP-----RGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPG 1152 + L GP GP GPPG +G + SG IG PG PG Sbjct: 904 RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERG-------------AAGSGGPIGPPGRPG 950 Query: 1153 PPGLPGTSYEELLSLLRG-------SEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYL 1205 P G PG + E+ + +G +G VG PGP GPPG+ G V D Sbjct: 951 PQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGD-PGQK 1009 Query: 1206 HTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVG 1265 T G GPPGPPGP GP G PG +GA A R F G Sbjct: 1010 GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGH----FGAKGDEGTRGF-NG 1064 Query: 1266 PPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGG 1325 PPGP G QG PG S +G + G G G G Sbjct: 1065 PPGPIGLQGLPGPSG---------------------EKGETGDVGPMGPPGPPGPRGPAG 1103 Query: 1326 AFGEAAGDRGPYG--TDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSES 1383 G A G +GP G ++GP G G E +G+ G+ G E V+ Sbjct: 1104 PNG-ADGPQGPPGGVGNLGPPGEKGEPGE----SGSPGIQG----------EPGVKGPRG 1148 Query: 1384 MQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQK 1443 + + G G PG PGP+GP G V + GPPG+ Sbjct: 1149 ERGEKGESGQ----PGEPGPPGPKGPTGDDGPKGNPGPV---------GFPGDPGPPGEG 1195 Query: 1444 GEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 G G G KGDRG G PG PG PGP G G G G + AG Sbjct: 1196 GPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAG 1238 Score = 432 bits (1110), Expect = e-120 Identities = 302/811 (37%), Positives = 343/811 (42%), Gaps = 195/811 (24%) Query: 561 ENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGH---PGPQGPKGQ---------- 607 E G L G PG G G GPKG GFPG PG G G G GP+G+ Sbjct: 705 EKGKL-GVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR 763 Query: 608 -----------KGSVGDPGMEGPMGQRGREGPM------GPRGEAGPPGS----GEKGER 646 KG+ G G GP G+RG GP GP+G GPPG G G+R Sbjct: 764 GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQR 823 Query: 647 GAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPP 706 G G G GPPG PG VGP+G++G GP G G G G GE GLPG G +G G P Sbjct: 824 GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP 883 Query: 707 GPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLT------ 760 GP G G+ GP GL G PG RGLPG G PG KG GP+GP G G GE+G Sbjct: 884 GPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPI 943 Query: 761 ---GMPGIRGPPGPSGDPGKPGLTGP---------QGPQGLPGTPGRPGI------KGEP 802 G PG +GPPG +G+ G PG GP QGP GLPG G PG+ KGE Sbjct: 944 GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1003 Query: 803 GAPGKIVTSEGSSMLTVPGPPGP------PGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQ 856 G PG+ T PGPPGP PGA G G PGA GP G G G + Sbjct: 1004 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1063 Query: 857 GPPGPPGPRGPPGPS-------------IPGPPGPRGPPG-EGLPGPPGPPGSFLSNSET 902 GPPGP G +G PGPS PGPPGPRGP G G GP GPPG + Sbjct: 1064 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1123 Query: 903 FLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPK 962 G PG G PG +G+ G GPRG +GE+G G G PGPPGP+GP Sbjct: 1124 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG------------QPGEPGPPGPKGPT 1171 Query: 963 GDKGDPGVPGALGIPSG---PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYIS 1019 GD G G PG +G P P EGG G G G PG PGS +G+ Sbjct: 1172 GDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE------- 1224 Query: 1020 EYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFS 1079 GPPGP G GP + E R G G Sbjct: 1225 ---------------NGPPGPLGKRGPAGSPGSEG--------------RQGGKGAKGDP 1255 Query: 1080 SSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMS 1139 +I + GP GP GP G G L L + + Sbjct: 1256 GAIGAPG-----------------KTGPVGPAGPAGKPGPDGLRGLPGS------VGQQG 1292 Query: 1140 SSGIS--IGLPGPPGPPGLPGTSYEELLSLLRGSE-FRGIVGPPGP---------PGPPG 1187 G + G PGP GPPGLPG + +G G++GPPG PGP G Sbjct: 1293 RPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQG 1352 Query: 1188 IPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFR 1247 PG + G S GP GPPG PGP GP G GA Sbjct: 1353 SPGQ----------KGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGA------------- 1389 Query: 1248 SELISYLTSPDVRSFIVGPPGPPGPQGPPGD 1278 T P G GPPG GPPG+ Sbjct: 1390 -------TGPGGPKGEKGVQGPPGHPGPPGE 1413 Score = 408 bits (1049), Expect = e-113 Identities = 296/795 (37%), Positives = 348/795 (43%), Gaps = 169/795 (21%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGR 625 +G GP GD G PG G++G G PG+PG +PG QGPKG G G PG G G RG Sbjct: 688 KGRTGPTGDPGPPGLMGEKGKLGVPGLPG---YPGRQGPKGSLGFPGFPGASGEKGARGL 744 Query: 626 EGPMGPRGEAGPPG----------SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGP 675 G GPRGE GP G +G+ G +G +G GPHGPPG G GP+G +G PGP Sbjct: 745 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 804 Query: 676 QGPPGPVGLQGL------RGEVGL---------PGV------KGDKGPMG------PPGP 708 +GPPGP G GL RGEVG PGV G+ GPMG PPGP Sbjct: 805 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 864 Query: 709 KGDQG---------------------EKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGP 747 G+QG + GP GL G PG RGLPG G PG KG GP+GP Sbjct: 865 PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 924 Query: 748 DGHQGPRGEQGLTGM---------PGIRGPPGPSGDPGKPGLTGP---------QGPQGL 789 G G GE+G G PG +GPPG +G+ G PG GP QGP GL Sbjct: 925 PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL 984 Query: 790 PGTPGRPGI------KGEPGAPGKIVTSEGSSMLTVPGPPGP------PGAMGPPGPPGA 837 PG G PG+ KGE G PG+ T PGPPGP PGA G G PGA Sbjct: 985 PGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGA 1044 Query: 838 PGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS-------------IPGPPGPRGPPG- 883 GP G G G + GPPGP G +G PGPS PGPPGPRGP G Sbjct: 1045 RGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGP 1104 Query: 884 EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSS 943 G GP GPPG + G PG G PG +G+ G GPRG +GE+G G Sbjct: 1105 NGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG------- 1157 Query: 944 SFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPS---------------------- 981 G PGPPGP+GP GD G G PG +G P P Sbjct: 1158 -----QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGE 1212 Query: 982 --EGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPG 1039 + GS +GPPGP G GP GS S G++ + + D G GP G Sbjct: 1213 PGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQG----GKGAKGDPGAIGAPGKTGPVG 1268 Query: 1040 PPGP---PGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDV 1096 P GP PGP + G L V R G + + + + R D Sbjct: 1269 PAGPAGKPGP-DGLRG-------LPGSVGQQGRPGATGQAGPPGPVGPPGLPGL--RGDA 1318 Query: 1097 RQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGL 1156 + G G GPPG G+ L + S M G S G GP GPPGL Sbjct: 1319 GAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGAS-GPIGPGGPPGL 1377 Query: 1157 PGTSYEELLSLLRGSEF-RGIVGPPGPPGPPGIPGNVWSSISVE---------DLSSYLH 1206 PG + + G +G G GPPG PG PG V + ++ D S + Sbjct: 1378 PGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQ 1437 Query: 1207 TAGLSFIPGPPGPPG 1221 G PG PG Sbjct: 1438 EDEAIPTGGAPGSPG 1452 Score = 407 bits (1047), Expect = e-113 Identities = 335/1002 (33%), Positives = 407/1002 (40%), Gaps = 196/1002 (19%) Query: 560 QENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGI--PGPLGHPGPQGPKGQKGSVGDPGME 617 +E L S P + + GP+G +G G P + PG L GP GP+G G +G PG++ Sbjct: 272 EEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVE-GPPGPEGPAGLIGPPGIQ 330 Query: 618 GPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPG----VPGSVGPKGSSGSP 673 G GP+G GE GPPG G G G GPPG +P G G P Sbjct: 331 G------NPGPVGDPGERGPPGRA-----GLPGSDGAPGPPGTSLMLPFRFGSGGGDKGP 379 Query: 674 ---------------------GPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQ 712 GP GP G G G G+ G PG+KG+ G +GP GP+G Q Sbjct: 380 VVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQ 439 Query: 713 GEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPS 772 G GP G G G G GA G PG G G G DG G GE+G G G +G PGP Sbjct: 440 GLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPP 499 Query: 773 GDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPP 832 G+ G+ G G GP+GLPG G G+ G G PG +PGPPG G GP Sbjct: 500 GEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPG------------IPGPPGVRGMDGPQ 547 Query: 833 GPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG-------PSIPGPPGPRGPPGEG 885 GP G+ GP G G PG Q QG PGP G GP G P +PG PG GPPG Sbjct: 548 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH- 606 Query: 886 LPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSF 945 PG GPPG+ + + GP G PGP G KG G G +GH+GE+G GF Sbjct: 607 -PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIG 665 Query: 946 GLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPG 1005 +G G PG +G G +G G G G P P G + V G PG PG GP G Sbjct: 666 VKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKG 725 Query: 1006 SISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVV 1065 S+ G S G+ G GP G GP TG + Sbjct: 726 SLGFPG----------FPGASGEKGARGLSGKSGPRGERGP----TGPRGQRGPRGATGK 771 Query: 1066 SYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSL 1125 S + + G E L Q + GP+GPPGPPG G Sbjct: 772 SGAKGTSGGDGPHGPP--GERGLPGPQGPNG-------FPGPKGPPGPPGKDG------- 815 Query: 1126 DYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEF-RGIVGPPGPPG 1184 + + G +G G GPPG PG + + G RG GPPGPPG Sbjct: 816 --------LPGHPGQRG-EVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPG 866 Query: 1185 PPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSD 1244 G+PG TAG G PGPPG PG GP G+ G + E Sbjct: 867 EQGLPG----------------TAGKEGTKGDPGPPGAPGKDGPAGLRG----FPGERG- 905 Query: 1245 SFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRG 1304 L P ++ GP GPPGP G PG+ RG Sbjct: 906 -----LPGTAGGPGLKGN-EGPSGPPGPAGSPGE------------------------RG 935 Query: 1305 SSYSSSMSTGGGGAGSLGAGGAFGEAA--GDRGPYGTDIGPGGGYGAAAEGGMY--AGNG 1360 ++ S G G G GA GE G++GP IGP G G G+ AG Sbjct: 936 AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP----IGPTGRDGVQGPVGLPGPAGPP 991 Query: 1361 GLLGADFAGDL-DYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAY 1419 G+ G D GD + + + ++ + + GPPG PGP GP G A Sbjct: 992 GVAGED--GDKGEVGDPGQKGTKGNKGE----------HGPPGPPGPIGPVGQPGAAGAD 1039 Query: 1420 SNVTA-DLMDFFQTYG-----------------AIQGPPGQKGE------MGTPGPKGDR 1455 A F G + GP G+KGE MG PGP G R Sbjct: 1040 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1099 Query: 1456 GPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 GPAGP G GP GP G G G G++ G I +P Sbjct: 1100 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEP 1141 Score = 382 bits (980), Expect = e-105 Identities = 230/534 (43%), Positives = 268/534 (50%), Gaps = 85/534 (15%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 L+G+ GP G G G G+RG G+ G GP G PGPQGP G G G PG +GP+G G Sbjct: 915 LKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTG 974 Query: 625 REGPMGP---RGEAGPPG-SGEKGERGAAGEPGP---------HGPPGVPGSVGP----- 666 R+G GP G AGPPG +GE G++G G+PG HGPPG PG +GP Sbjct: 975 RDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPG 1034 Query: 667 -------------------KGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPG 707 KG G+ G GPPGP+GLQGL G G G GD GPMGPPG Sbjct: 1035 AAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPG 1094 Query: 708 PKGDQGEKGPRGLTGE------------PGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRG 755 P G +G GP G G PG +G PG G PG +G G GP G +G +G Sbjct: 1095 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1154 Query: 756 EQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSS 815 E G G PG GP GP+GD G G GP G G PG PG G +G+ GA G +G Sbjct: 1155 ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDR-GEDGE- 1212 Query: 816 MLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIP-G 874 PG PG PG G GPPG G GPAG PG + +G G PG G PG + P G Sbjct: 1213 ----PGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVG 1268 Query: 875 PPGPRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQG 933 P GP G PG +GL G PG G T +GPPGP GPPG G +G G +G +G G Sbjct: 1269 PAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPG 1328 Query: 934 LPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSG 993 L G +G G PGPQG G KG+ G+PGA G P GP G Sbjct: 1329 LIGLIGPPGEQ---GEKGDRGLPGPQGSPGQKGEMGIPGASG-PIGPG-----------G 1373 Query: 994 PPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPV 1047 PPG PGP GP G+ ++G + GVQGPPG PGPPG V Sbjct: 1374 PPGLPGPAGPKGAKGATGPGGPKGEK-------------GVQGPPGHPGPPGEV 1414 Score = 362 bits (930), Expect = 1e-99 Identities = 223/501 (44%), Positives = 255/501 (50%), Gaps = 51/501 (10%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGRE 626 G G KG++G PG KG +G G G PGP G GP G G G+ G+PG GP G G + Sbjct: 995 GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1054 Query: 627 GPMGPRGEAGPPGS-------GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPP 679 G G RG GPPG G GE+G G+ GP GPPG PG GP G +G+ GPQGPP Sbjct: 1055 GDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPP 1114 Query: 680 GPVGLQGLRGEVGLPGVKGDKGPMGPP---GPKGDQGEKGPRGLTGEPGMRGLPGAVGEP 736 G VG G GE G PG G G G P GP+G++GEKG G GEPG G G G+ Sbjct: 1115 GGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD 1174 Query: 737 GAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRP 796 G KG GP G G GP GE G G G +G G G+PG+PG GP G G PG G+ Sbjct: 1175 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1234 Query: 797 GIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQ 856 G G PG+ G+ +G G G PGA+G PG G GPAGPAG PG L+ Sbjct: 1235 GPAGSPGSEGR----QGGK-----GAKGDPGAIGAPGKTGPVGPAGPAGKPGPD---GLR 1282 Query: 857 GPPGPPGPRGPPGPS-IPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPG 915 G PG G +G PG + GPPGP GPP GLPG G G+ L G GPPG G Sbjct: 1283 GLPGSVGQQGRPGATGQAGPPGPVGPP--GLPGLRGDAGAKGEKGHPGLIGLIGPPGEQG 1340 Query: 916 PKGDQGPPGPR---GHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPG 972 KGD+G PGP+ G +GE G+PG SG G GPPG PGP GPKG KG G Sbjct: 1341 EKGDRGLPGPQGSPGQKGEMGIPG--ASGPIGPG----GPPGLPGPAGPKGAKGATG--- 1391 Query: 973 ALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLS 1032 P GP G GPPG PGPPG + IQ D R Sbjct: 1392 ----PGGPKG--------EKGVQGPPGHPGPPGEVIQP-LPIQMPKKTRRSVDGSRLMQE 1438 Query: 1033 GVQGPP-GPPGPPGPVTTITG 1052 P G PG PG + I G Sbjct: 1439 DEAIPTGGAPGSPGGLEEIFG 1459 Score = 326 bits (836), Expect = 9e-89 Identities = 294/973 (30%), Positives = 347/973 (35%), Gaps = 289/973 (29%) Query: 708 PKGDQGEKGPRGLTGE----------------PGMRGLPGAVGEPGAKGAMGPAGPDGHQ 751 P ++ GPRGL GE PG G G +G PG +G GP G G + Sbjct: 283 PPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGER 342 Query: 752 GPRGEQGLTGMPGIRGP------------------------------------------- 768 GP G GL G G GP Sbjct: 343 GPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGP 402 Query: 769 ---------PGPSGDPGKPGL---------TGPQGPQGLPGTPGR--------------- 795 PGP G PG PGL GP+GPQGL G PG+ Sbjct: 403 PGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGM 462 Query: 796 ---PGIKGE------PGAPGKIVTSEGSSMLTVPGPP---------------------GP 825 PG+KG+ PG PG+ + +PGPP GP Sbjct: 463 PGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGP 522 Query: 826 PGAMGPPGPPGAPGPAGPAGLPGHQ---EVLNLQGPPGPPGPRGPPG-PSIPGPPGPRGP 881 G +GP GPPG PGP G G+ G Q L QG PGPPG +G PG +PGP G GP Sbjct: 523 RGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGP 582 Query: 882 PGE----GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGP---PGPR-------- 926 GE G PG PG PGS GPPG G GP G QGP PGPR Sbjct: 583 HGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGI 642 Query: 927 -------GHQGEQGLPGFS-----------------------------TSGSSSFG---- 946 G +GE G PGF T + G Sbjct: 643 RGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGL 702 Query: 947 ------LNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGP 1000 L + G PG PG QGPKG G PG PGA G G S GP GP G Sbjct: 703 MGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQ 762 Query: 1001 PGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGP---PGPPGPPGP--VTTITGETF 1055 GP G+ SG + + L G QGP PGP GPPGP + G Sbjct: 763 RGPRGATGKSGAKGTSG-GDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPG 821 Query: 1056 DYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPG 1115 E+ F V+ MG RG PGPPG Sbjct: 822 QRGEVG----------------FQGKTGPPGPPGVVGPQGAAGETGP--MGERGHPGPPG 863 Query: 1116 ASGDGSLLSLDYAELSSRILSYMSSSGIS--IGLPGPPGPPGLPGTSYEELLSLLRGSEF 1173 G+ L E + + G GL G PG GLPGT+ G Sbjct: 864 PPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTA--------GGPGL 915 Query: 1174 RGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSG 1233 +G GP GPPGP G PG G + GP GPPG PGP+GPPG +G Sbjct: 916 KGNEGPSGPPGPAGSPGE----------------RGAAGSGGPIGPPGRPGPQGPPGAAG 959 Query: 1234 ALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSS 1293 + P R + GP G PGP GPPG + D Sbjct: 960 EKGVPGEKGP-----------IGPTGRDGVQGPVGLPGPAGPPG---VAGEDGDKGEVGD 1005 Query: 1294 SSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEG 1353 + +G G G GA GA GE G RGP G +GA + Sbjct: 1006 PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGE-PGARGPQ-------GHFGAKGDE 1057 Query: 1354 GMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGIS 1413 G NG G + L E + + GPPG PGP+GP G + Sbjct: 1058 GTRGFNGP------PGPIGLQGLPGPSGEKGETGDV------GPMGPPGPPGPRGPAGPN 1105 Query: 1414 KVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHK 1473 QGPPG G +G PG KG+ G +G PG G PG +G + Sbjct: 1106 GA------------------DGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPR 1147 Query: 1474 GEKGDKGDQVYAG 1486 GE+G+KG+ G Sbjct: 1148 GERGEKGESGQPG 1160 Score = 298 bits (762), Expect = 3e-80 Identities = 176/393 (44%), Positives = 200/393 (50%), Gaps = 66/393 (16%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 L+G PGP G+ G G G G PG PG GP G G GP+G G VG+ G G G+ G Sbjct: 1071 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1130 Query: 625 REGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVG 683 G G +GE G G GE+GE+G +G+PG GPP GPKG +G GP+G PGPVG Sbjct: 1131 ESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP------GPKGPTGDDGPKGNPGPVG 1184 Query: 684 LQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGE---PGAKG 740 GD GP G GP+G G KG RG GEPG G PG GE PG G Sbjct: 1185 F------------PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1232 Query: 741 AMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKG 800 GPAG G +G +G +G G PG G PG +G G G G GP GL G PG G +G Sbjct: 1233 KRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG 1292 Query: 801 EPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPG 860 PGA G+ GPPG +GPPG PG G AG G GH ++ L GPPG Sbjct: 1293 RPGATGQ---------------AGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG 1337 Query: 861 P---------PGPRGPPG-------PSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFL 904 PGP+G PG P GP GP GPP GLPGP GP G+ Sbjct: 1338 EQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP--GLPGPAGPKGA--------- 1386 Query: 905 SGPPGPPGPPGPKGDQGPPGPRGHQGE--QGLP 935 G GP GP G KG QGPPG G GE Q LP Sbjct: 1387 KGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1419 Score = 98.2 bits (243), Expect = 5e-20 Identities = 117/387 (30%), Positives = 139/387 (35%), Gaps = 63/387 (16%) Query: 1150 PPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAG 1209 P PG E L S L GP G G G P + + VE AG Sbjct: 263 PQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAG 322 Query: 1210 LSFIPGPPGPPGP---PGPRGPPGVSGALATYAAENSDS------FR------------- 1247 L PG G PGP PG RGPPG +G + A FR Sbjct: 323 LIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVA 382 Query: 1248 -SELISYLTSPDVRSFIVGPPGP------PGPQGPPGDSRLLSTDASHSRGSSSSSHSSS 1300 E + R + GPPGP PGP G PG L +G S Sbjct: 383 AQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGL--------KGESGDLGPQG 434 Query: 1301 VRRGSSYSSSMSTGG--GGAGSLGAGGAFGE--AAGDRGPYGT-----------DIGPGG 1345 R + G G AG+ GA G G+ GDRG G D G G Sbjct: 435 PRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQG 494 Query: 1346 GYGAAAEGGMYAGNGGLLGADFAGDL-DYNELAVRVSESMQRQGLLQGMAYTVQGPPGQP 1404 G E G +G + G+ L + + ++GM QGP G Sbjct: 495 LPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMD-GPQGPKGSL 553 Query: 1405 GPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHP 1464 GPQG PG T GAI GP G+KG G PG G G GPPGHP Sbjct: 554 GPQGEPG-----PPGQQGTPGTQGLPGPQGAI-GPHGEKGPQGKPGLPGMPGSDGPPGHP 607 Query: 1465 ---GPPGPRGHKGEKGDKGDQVYAGRR 1488 GPPG +G++G G +G Y G R Sbjct: 608 GKEGPPGTKGNQGPSGPQGPLGYPGPR 634 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 488 bits (1255), Expect = e-137 Identities = 377/1030 (36%), Positives = 446/1030 (43%), Gaps = 178/1030 (17%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGH------------PGPQGPKGQKGSVGDP 614 G+ G +G G PG KGDRGF G PG+PG GH PG G +G G +G Sbjct: 434 GADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPR 493 Query: 615 GMEGPMGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSP 673 G+ G G RG GP GP G GPPG G G +G G GP G PG PG G G+ G P Sbjct: 494 GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP 553 Query: 674 GPQGPPGPVGLQGLRGEVGLPGVKGDKGPMG------PPGPKGDQGEKGPRGLTGEPGMR 727 GPQG GP G +G +G+ GLPG+ G GP G PPG KG+QG GP+G G PG R Sbjct: 554 GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 613 Query: 728 GLPGAVGEPGAKGAMGPAGPDGHQG------PRGEQGLTGMPGIRGPPGP---------S 772 G+ G G G KG G G DG G +G++G G+PG RG GP + Sbjct: 614 GVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPT 673 Query: 773 GDPGKPGLTGPQGP---QGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAM 829 GDPG PGL G +G GLPG PGR G KG G PG S + G GP G Sbjct: 674 GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER 733 Query: 830 GPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS----IPGPPGPRGPPG-E 884 GP GP G GP G G G + GP GPPG RG PGP PGP GP GPPG + Sbjct: 734 GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKD 793 Query: 885 GLPGPPGPPGSFLSNSETFLSGPPGPPGPPG------PKGDQGPPGPRGHQGEQGLPGFS 938 GLPG PG G +T GPPG GP G P G++G PGP G GEQGLPG Sbjct: 794 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPG-- 851 Query: 939 TSGSSSFGLNLQGPPGPPGPQGPKGDKGDPG---VPGALGIPS---------------GP 980 T+G + GPPG PG GP G +G PG +PG G P P Sbjct: 852 TAGKEGTKGD-PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 910 Query: 981 SEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGP 1040 E G++ + GPPG PGP GPPG+ G ++ D GVQGP G Sbjct: 911 GERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD-------GVQGPVGL 963 Query: 1041 PGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYL 1100 PGP GP + GE D E+ T G Sbjct: 964 PGPAGP-PGVAGEDGDKGEVGDP--GQKGTKG---------------------------- 992 Query: 1101 RQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGI--SIGLPGPPGP---PG 1155 + GP GPPGP G G D + + + G + G GPPGP G Sbjct: 993 NKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQG 1052 Query: 1156 LPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPG 1215 LPG S E +G G VGP GPPGPPG G AG + G Sbjct: 1053 LPGPSGE------KGET--GDVGPMGPPGPPGPRG----------------PAGPNGADG 1088 Query: 1216 PPGPPG------PPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGP 1269 P GPPG PPG +G PG SG+ R E S G PGP Sbjct: 1089 PQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE-----RGEKGESGQPGEPGP 1143 Query: 1270 PGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGE 1329 PGP+GP GD RG + G G G+ G GE Sbjct: 1144 PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE 1203 Query: 1330 AA-----GDRGPYGTDIGPG--GGYGAAAEGGMYAGNG--GLLG-ADFAGDLDYNELAVR 1379 G RGP G+ G GG GA + G G G +G A AG + L Sbjct: 1204 NGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR-G 1262 Query: 1380 VSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGP 1439 + S+ +QG + A GPPG GP G PG+ A + G I GP Sbjct: 1263 LPGSVGQQG--RPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGL-----IGLI-GP 1314 Query: 1440 PGQKGE---------MGTPGPKGDRG---PAGPPGHPGPPGPRGHKGEKGDKGDQVYAGR 1487 PG++GE G+PG KG+ G +GP G GPPG G G KG KG G Sbjct: 1315 PGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGP 1374 Query: 1488 RRRRSIAVKP 1497 + + + P Sbjct: 1375 KGEKGVQGPP 1384 Score = 482 bits (1241), Expect = e-135 Identities = 390/1091 (35%), Positives = 457/1091 (41%), Gaps = 244/1091 (22%) Query: 557 MMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGM 616 +++Q LRG PGP G G PGP G PG+PG+ G G GPQGP+G +G G PG Sbjct: 370 ILQQARLALRGPPGPMGYTGRPGPLGQ---PGSPGLKGESGDLGPQGPRGPQGLTGPPGK 426 Query: 617 EGPMGQRGREGPMGPRGEAGPPGS----------GEKGERG---AAGEPGPHG------- 656 G G+ G +G G G+ G G GEKG RG A G PGP G Sbjct: 427 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD 486 Query: 657 -----PPGVPGSVGPKGSSGSPGPQGPPGPVGLQGL------------RGEVGLPGVKGD 699 P G+PG GP+G G GP G PGP G++G+ +GE G PG +G Sbjct: 487 DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 546 Query: 700 KGPMGPPGPK---GDQGEKGPRGLTGEPGMRGL------PGAVGEPGAKGAMGPAGPD-- 748 G G PGP+ G GEKGP+G G PGM G PG G PG KG GP+GP Sbjct: 547 PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGP 606 Query: 749 -------------------GHQGPRGEQGL---------------TGMPGIRGPPG---- 770 GH+G +GE G G+PG RG G Sbjct: 607 LGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGP 666 Query: 771 -----PSGDPGKPGLTGPQGP---QGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGP 822 P+GDPG PGL G +G GLPG PGR G KG G PG S + G Sbjct: 667 KGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGK 726 Query: 823 PGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGP----SIPGPPGP 878 GP G GP GP G GP G G G + GP GPPG RG PGP PGP GP Sbjct: 727 SGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP 786 Query: 879 RGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPP---------GPPGPKGDQGPPGPRGH 928 GPPG +GLPG PG G +T GPPGPP G GP G++G PGP G Sbjct: 787 PGPPGKDGLPGHPGQRGEVGFQGKT---GPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 843 Query: 929 QGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDP---GVPGALGIP-------- 977 GEQGLPG T+G + GPPG PG GP G +G P G+PG G P Sbjct: 844 PGEQGLPG--TAGKEGTKGD-PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGP 900 Query: 978 -------SGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSY 1030 P E G++ + GPPG PGP GPPG+ G ++ D Sbjct: 901 SGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD----- 955 Query: 1031 LSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAV 1090 GVQGP G PGP GP + GE D E+ T G Sbjct: 956 --GVQGPVGLPGPAGP-PGVAGEDGDKGEVGD--PGQKGTKG------------------ 992 Query: 1091 LQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGI--SIGLP 1148 + GP GPPGP G G D + + + G + G Sbjct: 993 ----------NKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1042 Query: 1149 GPPGP---PGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYL 1205 GPPGP GLPG S E +G G VGP GPPGPPG G Sbjct: 1043 GPPGPIGLQGLPGPSGE------KGE--TGDVGPMGPPGPPGPRG--------------- 1079 Query: 1206 HTAGLSFIPGPPGPP------GPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDV 1259 AG + GP GPP GPPG +G PG SG+ R E Sbjct: 1080 -PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE-----RGEKG 1133 Query: 1260 RSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAG 1319 S G PGPPGP+GP GD RG + G G Sbjct: 1134 ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1193 Query: 1320 SLGAGGAFGE-----AAGDRGPYGTDIGPG--GGYGAAAEGGMYA--GNGGLLG-ADFAG 1369 G+ G GE G RGP G+ G GG GA + G G G +G A AG Sbjct: 1194 QPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAG 1253 Query: 1370 DLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNV-TADLMD 1428 + L + S+ +QG + A GPPG GP G PG+ A L+ Sbjct: 1254 KPGPDGLR-GLPGSVGQQG--RPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIG 1310 Query: 1429 FFQTYG-----------AIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHK---- 1473 G QG PGQKGEMG PG G GP GPPG PGP GP+G K Sbjct: 1311 LIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATG 1370 Query: 1474 --GEKGDKGDQ 1482 G KG+KG Q Sbjct: 1371 PGGPKGEKGVQ 1381 Score = 454 bits (1168), Expect = e-127 Identities = 358/1037 (34%), Positives = 423/1037 (40%), Gaps = 224/1037 (21%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPG--------- 615 + G PGP+G G GP G +G PG G PG G PG G G G+ G PG Sbjct: 290 VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 349 Query: 616 ----------------------------MEGPMGQRGREGPMGPRGEAGPPG-SGEKGER 646 + GP G G G GP G+ G PG GE G+ Sbjct: 350 GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 409 Query: 647 GAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDK------ 700 G G GP G G PG G +G +G+ G +G PG G++G RG GLPG+ G+K Sbjct: 410 GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 469 Query: 701 ------GPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPR 754 GP G G +GD GE GPRGL GE G RGL G G PG G G G DG QGP+ Sbjct: 470 GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 529 Query: 755 GEQGLTGMPGIRGPPGPSGDPGKPGLTGPQ---------GPQGLPGTPGRPGIKGEPGAP 805 G G G P GPPG G PG GL GPQ GPQG PG PG PG G PG P Sbjct: 530 GSLGPQGEP---GPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 586 Query: 806 GKIVTSEG-SSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQ-------------- 850 GK EG GP GP G +G PGP G G G GL GH+ Sbjct: 587 GK----EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGD 642 Query: 851 ----------EVLNLQGPPGPPGPRGPPGPS-IPGPPGPRGPPGE-GLPGPPGPPGSFLS 898 V +G GP GP+G GP+ PGPPG G G+ G+PG PG PG Sbjct: 643 IGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGP 702 Query: 899 NSETFLSGPPGP---------PGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNL 949 G PG G GP+G++GP GPRG +G +G G S + +S G Sbjct: 703 KGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGP 762 Query: 950 QGPPGP---PGPQGPK---GDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGP 1003 GPPG PGPQGP G KG PG PG G+P P + G +GPPGPPG GP Sbjct: 763 HGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGP 822 Query: 1004 PGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASH 1063 G+ +G G +G PGPPGPPG Sbjct: 823 QGAAGETGP-------------------MGERGHPGPPGPPG---------------EQG 848 Query: 1064 VVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGP-----RGPPGPPGASG 1118 + G +D A L+ + L GP GP GPPG +G Sbjct: 849 LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG 908 Query: 1119 DGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRG-------S 1171 + SG IG PG PGP G PG + E+ + +G Sbjct: 909 SPGERG-------------AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD 955 Query: 1172 EFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGV 1231 +G VG PGP GPPG+ G V D T G GPPGPPGP GP G PG Sbjct: 956 GVQGPVGLPGPAGPPGVAGEDGDKGEVGD-PGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1014 Query: 1232 SGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRG 1291 +GA A R F GPPGP G QG PG S Sbjct: 1015 AGADGEPGARGPQGH----FGAKGDEGTRGF-NGPPGPIGLQGLPGPSG----------- 1058 Query: 1292 SSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYG--TDIGPGGGYGA 1349 +G + G G G G G A G +GP G ++GP G G Sbjct: 1059 ----------EKGETGDVGPMGPPGPPGPRGPAGPNG-ADGPQGPPGGVGNLGPPGEKGE 1107 Query: 1350 AAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGP 1409 E +G+ G+ G E V+ + + G G PG PGP+GP Sbjct: 1108 PGE----SGSPGIQG----------EPGVKGPRGERGEKGESGQ----PGEPGPPGPKGP 1149 Query: 1410 PGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGP 1469 G V + GPPG+ G G G KGDRG G PG PG PGP Sbjct: 1150 TGDDGPKGNPGPV---------GFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP 1200 Query: 1470 RGHKGEKGDKGDQVYAG 1486 G G G G + AG Sbjct: 1201 TGENGPPGPLGKRGPAG 1217 Score = 432 bits (1110), Expect = e-120 Identities = 302/811 (37%), Positives = 343/811 (42%), Gaps = 195/811 (24%) Query: 561 ENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGH---PGPQGPKGQ---------- 607 E G L G PG G G GPKG GFPG PG G G G GP+G+ Sbjct: 684 EKGKL-GVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR 742 Query: 608 -----------KGSVGDPGMEGPMGQRGREGPM------GPRGEAGPPGS----GEKGER 646 KG+ G G GP G+RG GP GP+G GPPG G G+R Sbjct: 743 GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQR 802 Query: 647 GAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPP 706 G G G GPPG PG VGP+G++G GP G G G G GE GLPG G +G G P Sbjct: 803 GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP 862 Query: 707 GPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLT------ 760 GP G G+ GP GL G PG RGLPG G PG KG GP+GP G G GE+G Sbjct: 863 GPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPI 922 Query: 761 ---GMPGIRGPPGPSGDPGKPGLTGP---------QGPQGLPGTPGRPGI------KGEP 802 G PG +GPPG +G+ G PG GP QGP GLPG G PG+ KGE Sbjct: 923 GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 982 Query: 803 GAPGKIVTSEGSSMLTVPGPPGP------PGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQ 856 G PG+ T PGPPGP PGA G G PGA GP G G G + Sbjct: 983 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1042 Query: 857 GPPGPPGPRGPPGPS-------------IPGPPGPRGPPG-EGLPGPPGPPGSFLSNSET 902 GPPGP G +G PGPS PGPPGPRGP G G GP GPPG + Sbjct: 1043 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1102 Query: 903 FLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPK 962 G PG G PG +G+ G GPRG +GE+G G G PGPPGP+GP Sbjct: 1103 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG------------QPGEPGPPGPKGPT 1150 Query: 963 GDKGDPGVPGALGIPSG---PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYIS 1019 GD G G PG +G P P EGG G G G PG PGS +G+ Sbjct: 1151 GDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE------- 1203 Query: 1020 EYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFS 1079 GPPGP G GP + E R G G Sbjct: 1204 ---------------NGPPGPLGKRGPAGSPGSEG--------------RQGGKGAKGDP 1234 Query: 1080 SSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMS 1139 +I + GP GP GP G G L L + + Sbjct: 1235 GAIGAPG-----------------KTGPVGPAGPAGKPGPDGLRGLPGS------VGQQG 1271 Query: 1140 SSGIS--IGLPGPPGPPGLPGTSYEELLSLLRGSE-FRGIVGPPGP---------PGPPG 1187 G + G PGP GPPGLPG + +G G++GPPG PGP G Sbjct: 1272 RPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQG 1331 Query: 1188 IPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFR 1247 PG + G S GP GPPG PGP GP G GA Sbjct: 1332 SPGQ----------KGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGA------------- 1368 Query: 1248 SELISYLTSPDVRSFIVGPPGPPGPQGPPGD 1278 T P G GPPG GPPG+ Sbjct: 1369 -------TGPGGPKGEKGVQGPPGHPGPPGE 1392 Score = 408 bits (1049), Expect = e-113 Identities = 296/795 (37%), Positives = 348/795 (43%), Gaps = 169/795 (21%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGR 625 +G GP GD G PG G++G G PG+PG +PG QGPKG G G PG G G RG Sbjct: 667 KGRTGPTGDPGPPGLMGEKGKLGVPGLPG---YPGRQGPKGSLGFPGFPGASGEKGARGL 723 Query: 626 EGPMGPRGEAGPPG----------SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGP 675 G GPRGE GP G +G+ G +G +G GPHGPPG G GP+G +G PGP Sbjct: 724 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 783 Query: 676 QGPPGPVGLQGL------RGEVGL---------PGV------KGDKGPMG------PPGP 708 +GPPGP G GL RGEVG PGV G+ GPMG PPGP Sbjct: 784 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 843 Query: 709 KGDQG---------------------EKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGP 747 G+QG + GP GL G PG RGLPG G PG KG GP+GP Sbjct: 844 PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 903 Query: 748 DGHQGPRGEQGLTGM---------PGIRGPPGPSGDPGKPGLTGP---------QGPQGL 789 G G GE+G G PG +GPPG +G+ G PG GP QGP GL Sbjct: 904 PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL 963 Query: 790 PGTPGRPGI------KGEPGAPGKIVTSEGSSMLTVPGPPGP------PGAMGPPGPPGA 837 PG G PG+ KGE G PG+ T PGPPGP PGA G G PGA Sbjct: 964 PGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGA 1023 Query: 838 PGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS-------------IPGPPGPRGPPG- 883 GP G G G + GPPGP G +G PGPS PGPPGPRGP G Sbjct: 1024 RGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGP 1083 Query: 884 EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSS 943 G GP GPPG + G PG G PG +G+ G GPRG +GE+G G Sbjct: 1084 NGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG------- 1136 Query: 944 SFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPS---------------------- 981 G PGPPGP+GP GD G G PG +G P P Sbjct: 1137 -----QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGE 1191 Query: 982 --EGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPG 1039 + GS +GPPGP G GP GS S G++ + + D G GP G Sbjct: 1192 PGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQG----GKGAKGDPGAIGAPGKTGPVG 1247 Query: 1040 PPGP---PGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDV 1096 P GP PGP + G L V R G + + + + R D Sbjct: 1248 PAGPAGKPGP-DGLRG-------LPGSVGQQGRPGATGQAGPPGPVGPPGLPGL--RGDA 1297 Query: 1097 RQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGL 1156 + G G GPPG G+ L + S M G S G GP GPPGL Sbjct: 1298 GAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGAS-GPIGPGGPPGL 1356 Query: 1157 PGTSYEELLSLLRGSEF-RGIVGPPGPPGPPGIPGNVWSSISVE---------DLSSYLH 1206 PG + + G +G G GPPG PG PG V + ++ D S + Sbjct: 1357 PGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQ 1416 Query: 1207 TAGLSFIPGPPGPPG 1221 G PG PG Sbjct: 1417 EDEAIPTGGAPGSPG 1431 Score = 406 bits (1043), Expect = e-113 Identities = 331/983 (33%), Positives = 400/983 (40%), Gaps = 196/983 (19%) Query: 579 GPKGDRGFPGTPGI--PGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAG 636 GP+G +G G P + PG L GP GP+G G +G PG++G GP+G GE G Sbjct: 270 GPRGLKGEKGEPAVLEPGMLVE-GPPGPEGPAGLIGPPGIQG------NPGPVGDPGERG 322 Query: 637 PPGSGEKGERGAAGEPGPHGPPG----VPGSVGPKGSSGSP------------------- 673 PPG G G G GPPG +P G G P Sbjct: 323 PPGRA-----GLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLA 377 Query: 674 --GPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPG 731 GP GP G G G G+ G PG+KG+ G +GP GP+G QG GP G G G G G Sbjct: 378 LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADG 437 Query: 732 AVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPG 791 A G PG G G G DG G GE+G G G +G PGP G+ G+ G G GP+GLPG Sbjct: 438 ARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPG 497 Query: 792 TPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQE 851 G G+ G G PG +PGPPG G GP GP G+ GP G G PG Q Sbjct: 498 ESGPRGLLGPKGPPG------------IPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQG 545 Query: 852 VLNLQGPPGPPGPRGPPG-------PSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFL 904 QG PGP G GP G P +PG PG GPPG PG GPPG+ + + Sbjct: 546 TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH--PGKEGPPGTKGNQGPSGP 603 Query: 905 SGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGD 964 GP G PGP G KG G G +GH+GE+G GF +G G PG +G G Sbjct: 604 QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGP 663 Query: 965 KGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQS 1024 +G G G G P P G + V G PG PG GP GS+ G Sbjct: 664 EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPG----------FPG 713 Query: 1025 DSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISS 1084 S G+ G GP G GP TG + S + + G Sbjct: 714 ASGEKGARGLSGKSGPRGERGP----TGPRGQRGPRGATGKSGAKGTSGGDGPHGPP--G 767 Query: 1085 EDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGIS 1144 E L Q + GP+GPPGPPG G + + G Sbjct: 768 ERGLPGPQGPNG-------FPGPKGPPGPPGKDG---------------LPGHPGQRG-E 804 Query: 1145 IGLPGPPGPPGLPGTSYEELLSLLRGSEF-RGIVGPPGPPGPPGIPGNVWSSISVEDLSS 1203 +G G GPPG PG + + G RG GPPGPPG G+PG Sbjct: 805 VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPG------------- 851 Query: 1204 YLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFI 1263 TAG G PGPPG PG GP G+ G + E L P ++ Sbjct: 852 ---TAGKEGTKGDPGPPGAPGKDGPAGLRG----FPGERG------LPGTAGGPGLKGN- 897 Query: 1264 VGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGA 1323 GP GPPGP G PG+ RG++ S G G G Sbjct: 898 EGPSGPPGPAGSPGE------------------------RGAAGSGGPIGPPGRPGPQGP 933 Query: 1324 GGAFGEAA--GDRGPYGTDIGPGGGYGAAAEGGMY--AGNGGLLGADFAGDL-DYNELAV 1378 GA GE G++GP IGP G G G+ AG G+ G D GD + + Sbjct: 934 PGAAGEKGVPGEKGP----IGPTGRDGVQGPVGLPGPAGPPGVAGED--GDKGEVGDPGQ 987 Query: 1379 RVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTA-DLMDFFQTYG--- 1434 + ++ + + GPPG PGP GP G A A F G Sbjct: 988 KGTKGNKGE----------HGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEG 1037 Query: 1435 --------------AIQGPPGQKGE------MGTPGPKGDRGPAGPPGHPGPPGPRGHKG 1474 + GP G+KGE MG PGP G RGPAGP G GP GP G G Sbjct: 1038 TRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVG 1097 Query: 1475 EKGDKGDQVYAGRRRRRSIAVKP 1497 G G++ G I +P Sbjct: 1098 NLGPPGEKGEPGESGSPGIQGEP 1120 Score = 382 bits (980), Expect = e-105 Identities = 230/534 (43%), Positives = 268/534 (50%), Gaps = 85/534 (15%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 L+G+ GP G G G G+RG G+ G GP G PGPQGP G G G PG +GP+G G Sbjct: 894 LKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTG 953 Query: 625 REGPMGP---RGEAGPPG-SGEKGERGAAGEPGP---------HGPPGVPGSVGP----- 666 R+G GP G AGPPG +GE G++G G+PG HGPPG PG +GP Sbjct: 954 RDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPG 1013 Query: 667 -------------------KGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPG 707 KG G+ G GPPGP+GLQGL G G G GD GPMGPPG Sbjct: 1014 AAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPG 1073 Query: 708 PKGDQGEKGPRGLTGE------------PGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRG 755 P G +G GP G G PG +G PG G PG +G G GP G +G +G Sbjct: 1074 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1133 Query: 756 EQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSS 815 E G G PG GP GP+GD G G GP G G PG PG G +G+ GA G +G Sbjct: 1134 ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDR-GEDGE- 1191 Query: 816 MLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIP-G 874 PG PG PG G GPPG G GPAG PG + +G G PG G PG + P G Sbjct: 1192 ----PGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVG 1247 Query: 875 PPGPRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQG 933 P GP G PG +GL G PG G T +GPPGP GPPG G +G G +G +G G Sbjct: 1248 PAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPG 1307 Query: 934 LPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSG 993 L G +G G PGPQG G KG+ G+PGA G P GP G Sbjct: 1308 LIGLIGPPGEQ---GEKGDRGLPGPQGSPGQKGEMGIPGASG-PIGPG-----------G 1352 Query: 994 PPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPV 1047 PPG PGP GP G+ ++G + GVQGPPG PGPPG V Sbjct: 1353 PPGLPGPAGPKGAKGATGPGGPKGEK-------------GVQGPPGHPGPPGEV 1393 Score = 362 bits (930), Expect = 1e-99 Identities = 223/501 (44%), Positives = 255/501 (50%), Gaps = 51/501 (10%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGRE 626 G G KG++G PG KG +G G G PGP G GP G G G+ G+PG GP G G + Sbjct: 974 GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1033 Query: 627 GPMGPRGEAGPPGS-------GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPP 679 G G RG GPPG G GE+G G+ GP GPPG PG GP G +G+ GPQGPP Sbjct: 1034 GDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPP 1093 Query: 680 GPVGLQGLRGEVGLPGVKGDKGPMGPP---GPKGDQGEKGPRGLTGEPGMRGLPGAVGEP 736 G VG G GE G PG G G G P GP+G++GEKG G GEPG G G G+ Sbjct: 1094 GGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD 1153 Query: 737 GAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRP 796 G KG GP G G GP GE G G G +G G G+PG+PG GP G G PG G+ Sbjct: 1154 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1213 Query: 797 GIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQ 856 G G PG+ G+ +G G G PGA+G PG G GPAGPAG PG L+ Sbjct: 1214 GPAGSPGSEGR----QGGK-----GAKGDPGAIGAPGKTGPVGPAGPAGKPGPD---GLR 1261 Query: 857 GPPGPPGPRGPPGPS-IPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPG 915 G PG G +G PG + GPPGP GPP GLPG G G+ L G GPPG G Sbjct: 1262 GLPGSVGQQGRPGATGQAGPPGPVGPP--GLPGLRGDAGAKGEKGHPGLIGLIGPPGEQG 1319 Query: 916 PKGDQGPPGPR---GHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPG 972 KGD+G PGP+ G +GE G+PG SG G GPPG PGP GPKG KG G Sbjct: 1320 EKGDRGLPGPQGSPGQKGEMGIPG--ASGPIGPG----GPPGLPGPAGPKGAKGATG--- 1370 Query: 973 ALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLS 1032 P GP G GPPG PGPPG + IQ D R Sbjct: 1371 ----PGGPKG--------EKGVQGPPGHPGPPGEVIQP-LPIQMPKKTRRSVDGSRLMQE 1417 Query: 1033 GVQGPP-GPPGPPGPVTTITG 1052 P G PG PG + I G Sbjct: 1418 DEAIPTGGAPGSPGGLEEIFG 1438 Score = 326 bits (835), Expect = 1e-88 Identities = 294/969 (30%), Positives = 345/969 (35%), Gaps = 289/969 (29%) Query: 712 QGEKGPRGLTGE----------------PGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRG 755 Q GPRGL GE PG G G +G PG +G GP G G +GP G Sbjct: 266 QAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG 325 Query: 756 EQGLTGMPGIRGP----------------------------------------------- 768 GL G G GP Sbjct: 326 RAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM 385 Query: 769 -----PGPSGDPGKPGL---------TGPQGPQGLPGTPGR------------------P 796 PGP G PG PGL GP+GPQGL G PG+ P Sbjct: 386 GYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDP 445 Query: 797 GIKGE------PGAPGKIVTSEGSSMLTVPGPP---------------------GPPGAM 829 G+KG+ PG PG+ + +PGPP GP G + Sbjct: 446 GVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 505 Query: 830 GPPGPPGAPGPAGPAGLPGHQ---EVLNLQGPPGPPGPRGPPG-PSIPGPPGPRGPPGE- 884 GP GPPG PGP G G+ G Q L QG PGPPG +G PG +PGP G GP GE Sbjct: 506 GPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEK 565 Query: 885 ---GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGP---PGPR------------ 926 G PG PG PGS GPPG G GP G QGP PGPR Sbjct: 566 GPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLK 625 Query: 927 ---GHQGEQGLPGFS-----------------------------TSGSSSFG-------- 946 G +GE G PGF T + G Sbjct: 626 GHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEK 685 Query: 947 --LNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPP 1004 L + G PG PG QGPKG G PG PGA G G S GP GP G GP Sbjct: 686 GKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPR 745 Query: 1005 GSISSSGQEIQQYISEYMQSDSIRSYLSGVQGP---PGPPGPPGP--VTTITGETFDYSE 1059 G+ SG + + L G QGP PGP GPPGP + G E Sbjct: 746 GATGKSGAKGTSG-GDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE 804 Query: 1060 LASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGD 1119 + F V+ MG RG PGPPG G+ Sbjct: 805 VG----------------FQGKTGPPGPPGVVGPQGAAGETGP--MGERGHPGPPGPPGE 846 Query: 1120 GSLLSLDYAELSSRILSYMSSSGIS--IGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIV 1177 L E + + G GL G PG GLPGT+ G +G Sbjct: 847 QGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTA--------GGPGLKGNE 898 Query: 1178 GPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALAT 1237 GP GPPGP G PG G + GP GPPG PGP+GPPG +G Sbjct: 899 GPSGPPGPAGSPGE----------------RGAAGSGGPIGPPGRPGPQGPPGAAGEKGV 942 Query: 1238 YAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSH 1297 + P R + GP G PGP GPPG + D Sbjct: 943 PGEKGP-----------IGPTGRDGVQGPVGLPGPAGPPG---VAGEDGDKGEVGDPGQK 988 Query: 1298 SSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYA 1357 + +G G G GA GA GE G RGP G +GA + G Sbjct: 989 GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGE-PGARGPQ-------GHFGAKGDEGTRG 1040 Query: 1358 GNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFS 1417 NG G + L E + + GPPG PGP+GP G + Sbjct: 1041 FNGP------PGPIGLQGLPGPSGEKGETGDV------GPMGPPGPPGPRGPAGPNGA-- 1086 Query: 1418 AYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKG 1477 QGPPG G +G PG KG+ G +G PG G PG +G +GE+G Sbjct: 1087 ----------------DGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG 1130 Query: 1478 DKGDQVYAG 1486 +KG+ G Sbjct: 1131 EKGESGQPG 1139 Score = 298 bits (762), Expect = 3e-80 Identities = 176/393 (44%), Positives = 200/393 (50%), Gaps = 66/393 (16%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 L+G PGP G+ G G G G PG PG GP G G GP+G G VG+ G G G+ G Sbjct: 1050 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1109 Query: 625 REGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVG 683 G G +GE G G GE+GE+G +G+PG GPP GPKG +G GP+G PGPVG Sbjct: 1110 ESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP------GPKGPTGDDGPKGNPGPVG 1163 Query: 684 LQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGE---PGAKG 740 GD GP G GP+G G KG RG GEPG G PG GE PG G Sbjct: 1164 F------------PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1211 Query: 741 AMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKG 800 GPAG G +G +G +G G PG G PG +G G G G GP GL G PG G +G Sbjct: 1212 KRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG 1271 Query: 801 EPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPG 860 PGA G+ GPPG +GPPG PG G AG G GH ++ L GPPG Sbjct: 1272 RPGATGQ---------------AGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG 1316 Query: 861 P---------PGPRGPPG-------PSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFL 904 PGP+G PG P GP GP GPP GLPGP GP G+ Sbjct: 1317 EQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP--GLPGPAGPKGA--------- 1365 Query: 905 SGPPGPPGPPGPKGDQGPPGPRGHQGE--QGLP 935 G GP GP G KG QGPPG G GE Q LP Sbjct: 1366 KGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1398 Score = 248 bits (634), Expect = 2e-65 Identities = 256/852 (30%), Positives = 309/852 (36%), Gaps = 212/852 (24%) Query: 777 KPGLTGPQGPQGLPGTPGRPG-------IKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAM 829 +P GP+GL G G P ++G PG G + PGP G PG Sbjct: 262 EPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGER 321 Query: 830 GPPGPPGAPGPAGPAGLPG-------------------------------HQEVLNLQGP 858 GPPG G PG G G PG Q L L+GP Sbjct: 322 GPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGP 381 Query: 859 PGP------PGPRGPPG-PSIP------GPPGPRGPPGEGLPGPPGPPGSFLSNSETFLS 905 PGP PGP G PG P + GP GPRGP +GL GPPG G Sbjct: 382 PGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP--QGLTGPPGKAG---RRGRAGAD 436 Query: 906 GPPGPPGPPGPKGDQ------GPPGPRGHQGE---QGLPGFSTSGSSSFGLNLQGPPGPP 956 G G PG PG KGD+ G PG +GH+G+ QGLPG GP G P Sbjct: 437 GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLP 496 Query: 957 GPQGPK---GDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQE 1013 G GP+ G KG PG+PG G+ G ++ G PGPPG G PG+ G + Sbjct: 497 GESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQ 556 Query: 1014 --IQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTS 1071 I + + Q + G GPPG PG GP T Sbjct: 557 GAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGT--------------------KG 596 Query: 1072 GYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAEL- 1130 G S + V D +R G +G G PG GD + D E+ Sbjct: 597 NQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH--KGEKGEDGFPGFKGDIGVKG-DRGEVG 653 Query: 1131 --SSRILSYMSSSGISIGLPGPPGPPGL------------------------------PG 1158 SR G G PGPPGL PG Sbjct: 654 VPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPG 713 Query: 1159 TSYEELLSLLRGSE----FRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIP 1214 S E+ L G RG GP G GP G G + G +P Sbjct: 714 ASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAK-GTSGGDGPHGPPGERGLP 772 Query: 1215 GPPGP---PGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGP-- 1269 GP GP PGP GP GPPG G F+ + T P +VGP G Sbjct: 773 GPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGK-----TGPPGPPGVVGPQGAAG 827 Query: 1270 ----------PGPQGPPGDSRLLSTDASHSR-------GSSSSSHSSSVR--------RG 1304 PGP GPPG+ L T G+ + +R G Sbjct: 828 ETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPG 887 Query: 1305 SSYSSSMSTGGGGAGSLGAGGAFGE--AAGDRGPYGTD--IGPGGGYGAAAEGGMYAGNG 1360 ++ + G +G G G+ GE AAG GP G GP G GAA E G+ G Sbjct: 888 TAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGV-PGEK 946 Query: 1361 GLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYS 1420 G +G R G VQGP G PGP GPPG+ + Sbjct: 947 GPIG------------------PTGRDG--------VQGPVGLPGPAGPPGV----AGED 976 Query: 1421 NVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPP------GHPGPPGPRGHKG 1474 ++ D Q +G G KGE G PGP G GP G P G PG GP+GH G Sbjct: 977 GDKGEVGDPGQ-----KGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFG 1031 Query: 1475 EKGDKGDQVYAG 1486 KGD+G + + G Sbjct: 1032 AKGDEGTRGFNG 1043 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 488 bits (1255), Expect = e-137 Identities = 377/1030 (36%), Positives = 446/1030 (43%), Gaps = 178/1030 (17%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGH------------PGPQGPKGQKGSVGDP 614 G+ G +G G PG KGDRGF G PG+PG GH PG G +G G +G Sbjct: 541 GADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPR 600 Query: 615 GMEGPMGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSP 673 G+ G G RG GP GP G GPPG G G +G G GP G PG PG G G+ G P Sbjct: 601 GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP 660 Query: 674 GPQGPPGPVGLQGLRGEVGLPGVKGDKGPMG------PPGPKGDQGEKGPRGLTGEPGMR 727 GPQG GP G +G +G+ GLPG+ G GP G PPG KG+QG GP+G G PG R Sbjct: 661 GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 720 Query: 728 GLPGAVGEPGAKGAMGPAGPDGHQG------PRGEQGLTGMPGIRGPPGP---------S 772 G+ G G G KG G G DG G +G++G G+PG RG GP + Sbjct: 721 GVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPT 780 Query: 773 GDPGKPGLTGPQGP---QGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAM 829 GDPG PGL G +G GLPG PGR G KG G PG S + G GP G Sbjct: 781 GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER 840 Query: 830 GPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS----IPGPPGPRGPPG-E 884 GP GP G GP G G G + GP GPPG RG PGP PGP GP GPPG + Sbjct: 841 GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKD 900 Query: 885 GLPGPPGPPGSFLSNSETFLSGPPGPPGPPG------PKGDQGPPGPRGHQGEQGLPGFS 938 GLPG PG G +T GPPG GP G P G++G PGP G GEQGLPG Sbjct: 901 GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPG-- 958 Query: 939 TSGSSSFGLNLQGPPGPPGPQGPKGDKGDPG---VPGALGIPS---------------GP 980 T+G + GPPG PG GP G +G PG +PG G P P Sbjct: 959 TAGKEGTKGD-PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 1017 Query: 981 SEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGP 1040 E G++ + GPPG PGP GPPG+ G ++ D GVQGP G Sbjct: 1018 GERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD-------GVQGPVGL 1070 Query: 1041 PGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYL 1100 PGP GP + GE D E+ T G Sbjct: 1071 PGPAGP-PGVAGEDGDKGEVGDP--GQKGTKG---------------------------- 1099 Query: 1101 RQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGI--SIGLPGPPGP---PG 1155 + GP GPPGP G G D + + + G + G GPPGP G Sbjct: 1100 NKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQG 1159 Query: 1156 LPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPG 1215 LPG S E +G G VGP GPPGPPG G AG + G Sbjct: 1160 LPGPSGE------KGET--GDVGPMGPPGPPGPRG----------------PAGPNGADG 1195 Query: 1216 PPGPPG------PPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGP 1269 P GPPG PPG +G PG SG+ R E S G PGP Sbjct: 1196 PQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE-----RGEKGESGQPGEPGP 1250 Query: 1270 PGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGE 1329 PGP+GP GD RG + G G G+ G GE Sbjct: 1251 PGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE 1310 Query: 1330 AA-----GDRGPYGTDIGPG--GGYGAAAEGGMYAGNG--GLLG-ADFAGDLDYNELAVR 1379 G RGP G+ G GG GA + G G G +G A AG + L Sbjct: 1311 NGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR-G 1369 Query: 1380 VSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGP 1439 + S+ +QG + A GPPG GP G PG+ A + G I GP Sbjct: 1370 LPGSVGQQG--RPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGL-----IGLI-GP 1421 Query: 1440 PGQKGE---------MGTPGPKGDRG---PAGPPGHPGPPGPRGHKGEKGDKGDQVYAGR 1487 PG++GE G+PG KG+ G +GP G GPPG G G KG KG G Sbjct: 1422 PGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGP 1481 Query: 1488 RRRRSIAVKP 1497 + + + P Sbjct: 1482 KGEKGVQGPP 1491 Score = 482 bits (1241), Expect = e-135 Identities = 390/1091 (35%), Positives = 457/1091 (41%), Gaps = 244/1091 (22%) Query: 557 MMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGM 616 +++Q LRG PGP G G PGP G PG+PG+ G G GPQGP+G +G G PG Sbjct: 477 ILQQARLALRGPPGPMGYTGRPGPLGQ---PGSPGLKGESGDLGPQGPRGPQGLTGPPGK 533 Query: 617 EGPMGQRGREGPMGPRGEAGPPGS----------GEKGERG---AAGEPGPHG------- 656 G G+ G +G G G+ G G GEKG RG A G PGP G Sbjct: 534 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD 593 Query: 657 -----PPGVPGSVGPKGSSGSPGPQGPPGPVGLQGL------------RGEVGLPGVKGD 699 P G+PG GP+G G GP G PGP G++G+ +GE G PG +G Sbjct: 594 DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 653 Query: 700 KGPMGPPGPK---GDQGEKGPRGLTGEPGMRGL------PGAVGEPGAKGAMGPAGPD-- 748 G G PGP+ G GEKGP+G G PGM G PG G PG KG GP+GP Sbjct: 654 PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGP 713 Query: 749 -------------------GHQGPRGEQGL---------------TGMPGIRGPPG---- 770 GH+G +GE G G+PG RG G Sbjct: 714 LGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGP 773 Query: 771 -----PSGDPGKPGLTGPQGP---QGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGP 822 P+GDPG PGL G +G GLPG PGR G KG G PG S + G Sbjct: 774 KGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGK 833 Query: 823 PGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGP----SIPGPPGP 878 GP G GP GP G GP G G G + GP GPPG RG PGP PGP GP Sbjct: 834 SGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP 893 Query: 879 RGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPP---------GPPGPKGDQGPPGPRGH 928 GPPG +GLPG PG G +T GPPGPP G GP G++G PGP G Sbjct: 894 PGPPGKDGLPGHPGQRGEVGFQGKT---GPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 950 Query: 929 QGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDP---GVPGALGIP-------- 977 GEQGLPG T+G + GPPG PG GP G +G P G+PG G P Sbjct: 951 PGEQGLPG--TAGKEGTKGD-PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGP 1007 Query: 978 -------SGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSY 1030 P E G++ + GPPG PGP GPPG+ G ++ D Sbjct: 1008 SGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD----- 1062 Query: 1031 LSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAV 1090 GVQGP G PGP GP + GE D E+ T G Sbjct: 1063 --GVQGPVGLPGPAGP-PGVAGEDGDKGEVGD--PGQKGTKG------------------ 1099 Query: 1091 LQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGI--SIGLP 1148 + GP GPPGP G G D + + + G + G Sbjct: 1100 ----------NKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1149 Query: 1149 GPPGP---PGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYL 1205 GPPGP GLPG S E +G G VGP GPPGPPG G Sbjct: 1150 GPPGPIGLQGLPGPSGE------KGE--TGDVGPMGPPGPPGPRG--------------- 1186 Query: 1206 HTAGLSFIPGPPGPP------GPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDV 1259 AG + GP GPP GPPG +G PG SG+ R E Sbjct: 1187 -PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE-----RGEKG 1240 Query: 1260 RSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAG 1319 S G PGPPGP+GP GD RG + G G Sbjct: 1241 ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1300 Query: 1320 SLGAGGAFGE-----AAGDRGPYGTDIGPG--GGYGAAAEGGMYA--GNGGLLG-ADFAG 1369 G+ G GE G RGP G+ G GG GA + G G G +G A AG Sbjct: 1301 QPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAG 1360 Query: 1370 DLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNV-TADLMD 1428 + L + S+ +QG + A GPPG GP G PG+ A L+ Sbjct: 1361 KPGPDGLR-GLPGSVGQQG--RPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIG 1417 Query: 1429 FFQTYG-----------AIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHK---- 1473 G QG PGQKGEMG PG G GP GPPG PGP GP+G K Sbjct: 1418 LIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATG 1477 Query: 1474 --GEKGDKGDQ 1482 G KG+KG Q Sbjct: 1478 PGGPKGEKGVQ 1488 Score = 454 bits (1168), Expect = e-127 Identities = 358/1037 (34%), Positives = 423/1037 (40%), Gaps = 224/1037 (21%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPG--------- 615 + G PGP+G G GP G +G PG G PG G PG G G G+ G PG Sbjct: 397 VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 456 Query: 616 ----------------------------MEGPMGQRGREGPMGPRGEAGPPG-SGEKGER 646 + GP G G G GP G+ G PG GE G+ Sbjct: 457 GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 516 Query: 647 GAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDK------ 700 G G GP G G PG G +G +G+ G +G PG G++G RG GLPG+ G+K Sbjct: 517 GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 576 Query: 701 ------GPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPR 754 GP G G +GD GE GPRGL GE G RGL G G PG G G G DG QGP+ Sbjct: 577 GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 636 Query: 755 GEQGLTGMPGIRGPPGPSGDPGKPGLTGPQ---------GPQGLPGTPGRPGIKGEPGAP 805 G G G P GPPG G PG GL GPQ GPQG PG PG PG G PG P Sbjct: 637 GSLGPQGEP---GPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 693 Query: 806 GKIVTSEG-SSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQ-------------- 850 GK EG GP GP G +G PGP G G G GL GH+ Sbjct: 694 GK----EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGD 749 Query: 851 ----------EVLNLQGPPGPPGPRGPPGPS-IPGPPGPRGPPGE-GLPGPPGPPGSFLS 898 V +G GP GP+G GP+ PGPPG G G+ G+PG PG PG Sbjct: 750 IGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGP 809 Query: 899 NSETFLSGPPGP---------PGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNL 949 G PG G GP+G++GP GPRG +G +G G S + +S G Sbjct: 810 KGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGP 869 Query: 950 QGPPGP---PGPQGPK---GDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGP 1003 GPPG PGPQGP G KG PG PG G+P P + G +GPPGPPG GP Sbjct: 870 HGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGP 929 Query: 1004 PGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASH 1063 G+ +G G +G PGPPGPPG Sbjct: 930 QGAAGETGP-------------------MGERGHPGPPGPPG---------------EQG 955 Query: 1064 VVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGP-----RGPPGPPGASG 1118 + G +D A L+ + L GP GP GPPG +G Sbjct: 956 LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG 1015 Query: 1119 DGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRG-------S 1171 + SG IG PG PGP G PG + E+ + +G Sbjct: 1016 SPGERG-------------AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD 1062 Query: 1172 EFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGV 1231 +G VG PGP GPPG+ G V D T G GPPGPPGP GP G PG Sbjct: 1063 GVQGPVGLPGPAGPPGVAGEDGDKGEVGD-PGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1121 Query: 1232 SGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRG 1291 +GA A R F GPPGP G QG PG S Sbjct: 1122 AGADGEPGARGPQGH----FGAKGDEGTRGF-NGPPGPIGLQGLPGPSG----------- 1165 Query: 1292 SSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYG--TDIGPGGGYGA 1349 +G + G G G G G A G +GP G ++GP G G Sbjct: 1166 ----------EKGETGDVGPMGPPGPPGPRGPAGPNG-ADGPQGPPGGVGNLGPPGEKGE 1214 Query: 1350 AAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGP 1409 E +G+ G+ G E V+ + + G G PG PGP+GP Sbjct: 1215 PGE----SGSPGIQG----------EPGVKGPRGERGEKGESGQ----PGEPGPPGPKGP 1256 Query: 1410 PGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGP 1469 G V + GPPG+ G G G KGDRG G PG PG PGP Sbjct: 1257 TGDDGPKGNPGPV---------GFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP 1307 Query: 1470 RGHKGEKGDKGDQVYAG 1486 G G G G + AG Sbjct: 1308 TGENGPPGPLGKRGPAG 1324 Score = 432 bits (1110), Expect = e-120 Identities = 302/811 (37%), Positives = 343/811 (42%), Gaps = 195/811 (24%) Query: 561 ENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGH---PGPQGPKGQ---------- 607 E G L G PG G G GPKG GFPG PG G G G GP+G+ Sbjct: 791 EKGKL-GVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR 849 Query: 608 -----------KGSVGDPGMEGPMGQRGREGPM------GPRGEAGPPGS----GEKGER 646 KG+ G G GP G+RG GP GP+G GPPG G G+R Sbjct: 850 GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQR 909 Query: 647 GAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPP 706 G G G GPPG PG VGP+G++G GP G G G G GE GLPG G +G G P Sbjct: 910 GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP 969 Query: 707 GPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLT------ 760 GP G G+ GP GL G PG RGLPG G PG KG GP+GP G G GE+G Sbjct: 970 GPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPI 1029 Query: 761 ---GMPGIRGPPGPSGDPGKPGLTGP---------QGPQGLPGTPGRPGI------KGEP 802 G PG +GPPG +G+ G PG GP QGP GLPG G PG+ KGE Sbjct: 1030 GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1089 Query: 803 GAPGKIVTSEGSSMLTVPGPPGP------PGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQ 856 G PG+ T PGPPGP PGA G G PGA GP G G G + Sbjct: 1090 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1149 Query: 857 GPPGPPGPRGPPGPS-------------IPGPPGPRGPPG-EGLPGPPGPPGSFLSNSET 902 GPPGP G +G PGPS PGPPGPRGP G G GP GPPG + Sbjct: 1150 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1209 Query: 903 FLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPK 962 G PG G PG +G+ G GPRG +GE+G G G PGPPGP+GP Sbjct: 1210 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG------------QPGEPGPPGPKGPT 1257 Query: 963 GDKGDPGVPGALGIPSG---PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYIS 1019 GD G G PG +G P P EGG G G G PG PGS +G+ Sbjct: 1258 GDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE------- 1310 Query: 1020 EYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFS 1079 GPPGP G GP + E R G G Sbjct: 1311 ---------------NGPPGPLGKRGPAGSPGSEG--------------RQGGKGAKGDP 1341 Query: 1080 SSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMS 1139 +I + GP GP GP G G L L + + Sbjct: 1342 GAIGAPG-----------------KTGPVGPAGPAGKPGPDGLRGLPGS------VGQQG 1378 Query: 1140 SSGIS--IGLPGPPGPPGLPGTSYEELLSLLRGSE-FRGIVGPPGP---------PGPPG 1187 G + G PGP GPPGLPG + +G G++GPPG PGP G Sbjct: 1379 RPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQG 1438 Query: 1188 IPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFR 1247 PG + G S GP GPPG PGP GP G GA Sbjct: 1439 SPGQ----------KGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGA------------- 1475 Query: 1248 SELISYLTSPDVRSFIVGPPGPPGPQGPPGD 1278 T P G GPPG GPPG+ Sbjct: 1476 -------TGPGGPKGEKGVQGPPGHPGPPGE 1499 Score = 408 bits (1049), Expect = e-113 Identities = 296/795 (37%), Positives = 348/795 (43%), Gaps = 169/795 (21%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGR 625 +G GP GD G PG G++G G PG+PG +PG QGPKG G G PG G G RG Sbjct: 774 KGRTGPTGDPGPPGLMGEKGKLGVPGLPG---YPGRQGPKGSLGFPGFPGASGEKGARGL 830 Query: 626 EGPMGPRGEAGPPG----------SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGP 675 G GPRGE GP G +G+ G +G +G GPHGPPG G GP+G +G PGP Sbjct: 831 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 890 Query: 676 QGPPGPVGLQGL------RGEVGL---------PGV------KGDKGPMG------PPGP 708 +GPPGP G GL RGEVG PGV G+ GPMG PPGP Sbjct: 891 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 950 Query: 709 KGDQG---------------------EKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGP 747 G+QG + GP GL G PG RGLPG G PG KG GP+GP Sbjct: 951 PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 1010 Query: 748 DGHQGPRGEQGLTGM---------PGIRGPPGPSGDPGKPGLTGP---------QGPQGL 789 G G GE+G G PG +GPPG +G+ G PG GP QGP GL Sbjct: 1011 PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL 1070 Query: 790 PGTPGRPGI------KGEPGAPGKIVTSEGSSMLTVPGPPGP------PGAMGPPGPPGA 837 PG G PG+ KGE G PG+ T PGPPGP PGA G G PGA Sbjct: 1071 PGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGA 1130 Query: 838 PGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS-------------IPGPPGPRGPPG- 883 GP G G G + GPPGP G +G PGPS PGPPGPRGP G Sbjct: 1131 RGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGP 1190 Query: 884 EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSS 943 G GP GPPG + G PG G PG +G+ G GPRG +GE+G G Sbjct: 1191 NGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG------- 1243 Query: 944 SFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPS---------------------- 981 G PGPPGP+GP GD G G PG +G P P Sbjct: 1244 -----QPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGE 1298 Query: 982 --EGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPG 1039 + GS +GPPGP G GP GS S G++ + + D G GP G Sbjct: 1299 PGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQG----GKGAKGDPGAIGAPGKTGPVG 1354 Query: 1040 PPGP---PGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDV 1096 P GP PGP + G L V R G + + + + R D Sbjct: 1355 PAGPAGKPGP-DGLRG-------LPGSVGQQGRPGATGQAGPPGPVGPPGLPGL--RGDA 1404 Query: 1097 RQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGL 1156 + G G GPPG G+ L + S M G S G GP GPPGL Sbjct: 1405 GAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGAS-GPIGPGGPPGL 1463 Query: 1157 PGTSYEELLSLLRGSEF-RGIVGPPGPPGPPGIPGNVWSSISVE---------DLSSYLH 1206 PG + + G +G G GPPG PG PG V + ++ D S + Sbjct: 1464 PGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQ 1523 Query: 1207 TAGLSFIPGPPGPPG 1221 G PG PG Sbjct: 1524 EDEAIPTGGAPGSPG 1538 Score = 406 bits (1043), Expect = e-113 Identities = 331/983 (33%), Positives = 400/983 (40%), Gaps = 196/983 (19%) Query: 579 GPKGDRGFPGTPGI--PGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAG 636 GP+G +G G P + PG L GP GP+G G +G PG++G GP+G GE G Sbjct: 377 GPRGLKGEKGEPAVLEPGMLVE-GPPGPEGPAGLIGPPGIQG------NPGPVGDPGERG 429 Query: 637 PPGSGEKGERGAAGEPGPHGPPG----VPGSVGPKGSSGSP------------------- 673 PPG G G G GPPG +P G G P Sbjct: 430 PPGRA-----GLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLA 484 Query: 674 --GPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPG 731 GP GP G G G G+ G PG+KG+ G +GP GP+G QG GP G G G G G Sbjct: 485 LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADG 544 Query: 732 AVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPG 791 A G PG G G G DG G GE+G G G +G PGP G+ G+ G G GP+GLPG Sbjct: 545 ARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPG 604 Query: 792 TPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQE 851 G G+ G G PG +PGPPG G GP GP G+ GP G G PG Q Sbjct: 605 ESGPRGLLGPKGPPG------------IPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQG 652 Query: 852 VLNLQGPPGPPGPRGPPG-------PSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFL 904 QG PGP G GP G P +PG PG GPPG PG GPPG+ + + Sbjct: 653 TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH--PGKEGPPGTKGNQGPSGP 710 Query: 905 SGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGD 964 GP G PGP G KG G G +GH+GE+G GF +G G PG +G G Sbjct: 711 QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGP 770 Query: 965 KGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQS 1024 +G G G G P P G + V G PG PG GP GS+ G Sbjct: 771 EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPG----------FPG 820 Query: 1025 DSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISS 1084 S G+ G GP G GP TG + S + + G Sbjct: 821 ASGEKGARGLSGKSGPRGERGP----TGPRGQRGPRGATGKSGAKGTSGGDGPHGPP--G 874 Query: 1085 EDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGIS 1144 E L Q + GP+GPPGPPG G + + G Sbjct: 875 ERGLPGPQGPNG-------FPGPKGPPGPPGKDG---------------LPGHPGQRG-E 911 Query: 1145 IGLPGPPGPPGLPGTSYEELLSLLRGSEF-RGIVGPPGPPGPPGIPGNVWSSISVEDLSS 1203 +G G GPPG PG + + G RG GPPGPPG G+PG Sbjct: 912 VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPG------------- 958 Query: 1204 YLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFI 1263 TAG G PGPPG PG GP G+ G + E L P ++ Sbjct: 959 ---TAGKEGTKGDPGPPGAPGKDGPAGLRG----FPGERG------LPGTAGGPGLKGN- 1004 Query: 1264 VGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGA 1323 GP GPPGP G PG+ RG++ S G G G Sbjct: 1005 EGPSGPPGPAGSPGE------------------------RGAAGSGGPIGPPGRPGPQGP 1040 Query: 1324 GGAFGEAA--GDRGPYGTDIGPGGGYGAAAEGGMY--AGNGGLLGADFAGDL-DYNELAV 1378 GA GE G++GP IGP G G G+ AG G+ G D GD + + Sbjct: 1041 PGAAGEKGVPGEKGP----IGPTGRDGVQGPVGLPGPAGPPGVAGED--GDKGEVGDPGQ 1094 Query: 1379 RVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTA-DLMDFFQTYG--- 1434 + ++ + + GPPG PGP GP G A A F G Sbjct: 1095 KGTKGNKGE----------HGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEG 1144 Query: 1435 --------------AIQGPPGQKGE------MGTPGPKGDRGPAGPPGHPGPPGPRGHKG 1474 + GP G+KGE MG PGP G RGPAGP G GP GP G G Sbjct: 1145 TRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVG 1204 Query: 1475 EKGDKGDQVYAGRRRRRSIAVKP 1497 G G++ G I +P Sbjct: 1205 NLGPPGEKGEPGESGSPGIQGEP 1227 Score = 382 bits (980), Expect = e-105 Identities = 230/534 (43%), Positives = 268/534 (50%), Gaps = 85/534 (15%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 L+G+ GP G G G G+RG G+ G GP G PGPQGP G G G PG +GP+G G Sbjct: 1001 LKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTG 1060 Query: 625 REGPMGP---RGEAGPPG-SGEKGERGAAGEPGP---------HGPPGVPGSVGP----- 666 R+G GP G AGPPG +GE G++G G+PG HGPPG PG +GP Sbjct: 1061 RDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPG 1120 Query: 667 -------------------KGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPG 707 KG G+ G GPPGP+GLQGL G G G GD GPMGPPG Sbjct: 1121 AAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPG 1180 Query: 708 PKGDQGEKGPRGLTGE------------PGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRG 755 P G +G GP G G PG +G PG G PG +G G GP G +G +G Sbjct: 1181 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1240 Query: 756 EQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSS 815 E G G PG GP GP+GD G G GP G G PG PG G +G+ GA G +G Sbjct: 1241 ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDR-GEDGE- 1298 Query: 816 MLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIP-G 874 PG PG PG G GPPG G GPAG PG + +G G PG G PG + P G Sbjct: 1299 ----PGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVG 1354 Query: 875 PPGPRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQG 933 P GP G PG +GL G PG G T +GPPGP GPPG G +G G +G +G G Sbjct: 1355 PAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPG 1414 Query: 934 LPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSG 993 L G +G G PGPQG G KG+ G+PGA G P GP G Sbjct: 1415 LIGLIGPPGEQ---GEKGDRGLPGPQGSPGQKGEMGIPGASG-PIGPG-----------G 1459 Query: 994 PPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPV 1047 PPG PGP GP G+ ++G + GVQGPPG PGPPG V Sbjct: 1460 PPGLPGPAGPKGAKGATGPGGPKGEK-------------GVQGPPGHPGPPGEV 1500 Score = 362 bits (930), Expect = 1e-99 Identities = 223/501 (44%), Positives = 255/501 (50%), Gaps = 51/501 (10%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGRE 626 G G KG++G PG KG +G G G PGP G GP G G G+ G+PG GP G G + Sbjct: 1081 GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAK 1140 Query: 627 GPMGPRGEAGPPGS-------GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPP 679 G G RG GPPG G GE+G G+ GP GPPG PG GP G +G+ GPQGPP Sbjct: 1141 GDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPP 1200 Query: 680 GPVGLQGLRGEVGLPGVKGDKGPMGPP---GPKGDQGEKGPRGLTGEPGMRGLPGAVGEP 736 G VG G GE G PG G G G P GP+G++GEKG G GEPG G G G+ Sbjct: 1201 GGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD 1260 Query: 737 GAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRP 796 G KG GP G G GP GE G G G +G G G+PG+PG GP G G PG G+ Sbjct: 1261 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1320 Query: 797 GIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQ 856 G G PG+ G+ +G G G PGA+G PG G GPAGPAG PG L+ Sbjct: 1321 GPAGSPGSEGR----QGGK-----GAKGDPGAIGAPGKTGPVGPAGPAGKPGPD---GLR 1368 Query: 857 GPPGPPGPRGPPGPS-IPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPG 915 G PG G +G PG + GPPGP GPP GLPG G G+ L G GPPG G Sbjct: 1369 GLPGSVGQQGRPGATGQAGPPGPVGPP--GLPGLRGDAGAKGEKGHPGLIGLIGPPGEQG 1426 Query: 916 PKGDQGPPGPR---GHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPG 972 KGD+G PGP+ G +GE G+PG SG G GPPG PGP GPKG KG G Sbjct: 1427 EKGDRGLPGPQGSPGQKGEMGIPG--ASGPIGPG----GPPGLPGPAGPKGAKGATG--- 1477 Query: 973 ALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLS 1032 P GP G GPPG PGPPG + IQ D R Sbjct: 1478 ----PGGPKG--------EKGVQGPPGHPGPPGEVIQP-LPIQMPKKTRRSVDGSRLMQE 1524 Query: 1033 GVQGPP-GPPGPPGPVTTITG 1052 P G PG PG + I G Sbjct: 1525 DEAIPTGGAPGSPGGLEEIFG 1545 Score = 298 bits (762), Expect = 3e-80 Identities = 176/393 (44%), Positives = 200/393 (50%), Gaps = 66/393 (16%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 L+G PGP G+ G G G G PG PG GP G G GP+G G VG+ G G G+ G Sbjct: 1157 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1216 Query: 625 REGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVG 683 G G +GE G G GE+GE+G +G+PG GPP GPKG +G GP+G PGPVG Sbjct: 1217 ESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP------GPKGPTGDDGPKGNPGPVG 1270 Query: 684 LQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGE---PGAKG 740 GD GP G GP+G G KG RG GEPG G PG GE PG G Sbjct: 1271 F------------PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1318 Query: 741 AMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKG 800 GPAG G +G +G +G G PG G PG +G G G G GP GL G PG G +G Sbjct: 1319 KRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG 1378 Query: 801 EPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPG 860 PGA G+ GPPG +GPPG PG G AG G GH ++ L GPPG Sbjct: 1379 RPGATGQ---------------AGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG 1423 Query: 861 P---------PGPRGPPG-------PSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFL 904 PGP+G PG P GP GP GPP GLPGP GP G+ Sbjct: 1424 EQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP--GLPGPAGPKGA--------- 1472 Query: 905 SGPPGPPGPPGPKGDQGPPGPRGHQGE--QGLP 935 G GP GP G KG QGPPG G GE Q LP Sbjct: 1473 KGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1505 Score = 48.5 bits (114), Expect = 5e-05 Identities = 28/59 (47%), Positives = 29/59 (49%), Gaps = 13/59 (22%) Query: 1435 AIQGPPGQKGEMGTP----------GPKGDRGPA---GPPGHPGPPGPRGHKGEKGDKG 1480 A GP G KGE G P GP G GPA GPPG G PGP G GE+G G Sbjct: 374 AAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG 432 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 487 bits (1254), Expect = e-137 Identities = 359/1032 (34%), Positives = 416/1032 (40%), Gaps = 184/1032 (17%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPG---------- 615 RG G KG+ G+PGP+G G PGTPG PGP G PGP GP G G+ Sbjct: 134 RGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGG 193 Query: 616 -----MEGPMGQRGREGPMGPRGEAGPPG----SGEKGERGAAGEPGPHGPPGVPGSVGP 666 M+GPMG G GP GP G GP G GE GE G +G GP GPPG PG G Sbjct: 194 AQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 253 Query: 667 KGSSGSP---GPQGPPGPVGLQGLRGEVGLPGVKGD------------------KGPMGP 705 G +G P G +GPPGP G +G G GLPGVKG KG G Sbjct: 254 DGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 313 Query: 706 PGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGI 765 PG G G GPRGL GE G G GA G G G GPAGP G GP G G G PG Sbjct: 314 PGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGA 373 Query: 766 RGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGP 825 +G GP+G G G GP+G G PG+PG G G PG G + + G PG Sbjct: 374 KGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 433 Query: 826 PGAMGPPGPPGAPGPAGPAGLPGHQEVLNL---QGP---PGPPGPRGPPGPS-------- 871 PG GPPGP GA GP GP G G + QGP PGP GP+G PGP+ Sbjct: 434 PGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGA 493 Query: 872 --IPGPPGPRGPPGE-------------GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGP 916 PG GP GPPGE GL GP G PG + L+GP G G PG Sbjct: 494 RGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG---ERGPSGLAGPKGANGDPGR 550 Query: 917 KGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQ------------GPKGD 964 G+ G PG RG G G G S G PGPPGPQ GPKG Sbjct: 551 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGA 610 Query: 965 KGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQS 1024 G+PG G G+P P G +G GPPGP GP G G Sbjct: 611 NGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGP--------- 661 Query: 1025 DSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISS 1084 SG QG PGPPGPPG + A +V G+ S Sbjct: 662 -------SGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG--- 711 Query: 1085 EDILAVLQRDDVRQYLRQYLMGPR---------------GPPGPPGASGDGSLLSLDYAE 1129 Q L GPR GP GPPGA G L + Sbjct: 712 ----------------AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGER 755 Query: 1130 LSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIP 1189 ++ I G +G GP G PG G RG+ GP GPPGP G Sbjct: 756 GAAGIAGPKGDRG-DVGEKGPEGAPGKDGG--------------RGLTGPIGPPGPAGAN 800 Query: 1190 GNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSE 1249 G + + G G GPPGP G GPPG G + + + Sbjct: 801 GEK-GEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD 859 Query: 1250 L-------ISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVR 1302 S P + + GP G G QGPPG + + R S+ + Sbjct: 860 AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGAT---GFPGAAGRVGPPGSNGNPGP 916 Query: 1303 RGSSYSSSMSTGGGGAGSLGAGGAFGEAA--GDRGPYGT-----DIGPGGGYGAAAEGGM 1355 G S G G G G GE G GP G D GP G G G+ Sbjct: 917 PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 976 Query: 1356 YAGNGGLLG-ADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISK 1414 AG G++G G+ + L E +QG A G G PGP GPPG++ Sbjct: 977 -AGQRGIVGLPGQRGERGFPGLPGPSGEP-GKQG-----APGASGDRGPPGPVGPPGLTG 1029 Query: 1415 VFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKG 1474 + D GPPG+ G G G +G+ G G PG PGPPG G G Sbjct: 1030 PAGEPGREGSPGAD---------GPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAG 1080 Query: 1475 EKGDKGDQVYAG 1486 G +GD+ AG Sbjct: 1081 PTGKQGDRGEAG 1092 Score = 483 bits (1242), Expect = e-136 Identities = 365/1021 (35%), Positives = 424/1021 (41%), Gaps = 203/1021 (19%) Query: 560 QENGNLRGSPGPKGDM---GSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGM 616 Q N G PG G M G PGP G G G G PG G GP GP+G +G G PG+ Sbjct: 224 QGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGL 283 Query: 617 EGPMGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVP---------GSVGP 666 G G RG G G +GEAG PG GE G G G PGP GP G+P G+ G Sbjct: 284 PGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGA 343 Query: 667 KGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEK---------GP 717 +G+ G PGP GPPGPVG G G G PG KG+ GP G GP+G QG + GP Sbjct: 344 RGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGP 403 Query: 718 RGLTGEPGMRGLPGA---------VGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGP 768 G +G PG G+PGA G PG G GP GP G GP G +G TG PGI G Sbjct: 404 AGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGF 463 Query: 769 PGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKI-------------------- 808 G G G+PG GPQG G G G+ G +GEPG G I Sbjct: 464 KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGL 523 Query: 809 ------VTSEGSSMLTVP-GPPGPPGAMGPPGPPGA------PGPAGPAGLPGHQEVLNL 855 G S L P G G PG G PG PGA PG AGP G G Sbjct: 524 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE 583 Query: 856 QGPPGPPGPRGPPG-PSIPGPPGPRGPPGE-------GLPGPPGPPGSFLSNSETFLSGP 907 G PGPPGP+G G P + G PGP+G GE GLPG PG G + ET +GP Sbjct: 584 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP 643 Query: 908 PGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGD 967 PGP GP G +G+QG PGP G QG G PG G + G G PG GP+G++G Sbjct: 644 PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 703 Query: 968 P---GVPGALGI--PSG-PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEY 1021 P G PGA G+ P G P G+ SGP GPPG GPPG G+ I+ Sbjct: 704 PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAG- 762 Query: 1022 MQSDSIRSYLSGVQGPP---------GPPGPPGPVTTITGETFDYSELASHVVSYLRTSG 1072 + D G +G P GP GPPGP G + E+ G Sbjct: 763 PKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGP----AGANGEKGEVG--------PPG 810 Query: 1073 YGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSS 1132 S + E G GPPGP G +G A+ Sbjct: 811 PAGSAGARGAPGE-------------------RGETGPPGPAGFAGPPGADGQPGAKGEQ 851 Query: 1133 RILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNV 1192 + G PGP GP G PG ++ +G+ RG GPPG G PG G V Sbjct: 852 GEAGQKGDA----GAPGPQGPSGAPGPQGPTGVTGPKGA--RGAQGPPGATGFPGAAGRV 905 Query: 1193 WSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELIS 1252 G + PGPPGPPGP G GP G G + Sbjct: 906 -------------GPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ----- 947 Query: 1253 YLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSV-----RRGSSY 1307 GP GPPG +G PGD + A G + + +RG Sbjct: 948 ------------GPAGPPGEKGEPGDDG--PSGAEGPPGPQGLAGQRGIVGLPGQRGERG 993 Query: 1308 SSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADF 1367 + G G GA G A+GDRGP G +GP G G A E G G GAD Sbjct: 994 FPGLPGPSGEPGKQGAPG----ASGDRGPPG-PVGPPGLTGPAGE----PGREGSPGADG 1044 Query: 1368 AGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLM 1427 D A V G + A GPPG PGP GP Sbjct: 1045 PPGRDG---AAGVKGDRGETGAVG--APGAPGPPGSPGPAGP------------------ 1081 Query: 1428 DFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGR 1487 G G +GE G GP G GPAG G GP GPRG KGE G+ G++ G Sbjct: 1082 ---------TGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGH 1132 Query: 1488 R 1488 R Sbjct: 1133 R 1133 Score = 478 bits (1230), Expect = e-134 Identities = 368/1031 (35%), Positives = 441/1031 (42%), Gaps = 196/1031 (19%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMG---QR 623 G PG G+ G PGP+G RGFPGTPG+PG GH G G G KG G PG++G G + Sbjct: 258 GKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN 317 Query: 624 GREGPMGPRG------EAGPPGS----GEKGERGAAGEPGPHGP---PGVPGSVGPKGSS 670 G GPMGPRG GP G+ G G+ G AG PGP GP PG PG+ G KG + Sbjct: 318 GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEA 377 Query: 671 GSPGPQGP---------------PGPVGLQGLRGEVGLPGVKGDKG------------PM 703 G G +GP PGP G G G G+PG KG G P Sbjct: 378 GPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPR 437 Query: 704 GPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGM- 762 GPPGP+G G GP+G TGEPG+ G G E G KG GPAGP G GP GE+G G Sbjct: 438 GPPGPQGATGPLGPKGQTGEPGIAGFKG---EQGPKGEPGPAGPQGAPGPAGEEGKRGAR 494 Query: 763 -----------PGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTS 811 PG RG PG G PG+ GL GP+G G G G G KG G PG+ Sbjct: 495 GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR---- 550 Query: 812 EGSSMLTVPGPPGPPGAMGPPGPPGAPGP---AGPAGLPGHQEVLNLQGPPGPPGPRGPP 868 PG PG PGA G G PG GP GP+G PG GPPGP G RG P Sbjct: 551 --------PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGED---GRPGPPGPQGARGQP 599 Query: 869 GP-SIPGPPGPRGPPGE----GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPP 923 G PGP G G PG+ GLPG PG G + ET +GPPGP GP G +G+QG P Sbjct: 600 GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAP 659 Query: 924 GPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGV---PGALGI--PS 978 GP G QG G PG G + G G PG GP+G++G PG PGA G+ P Sbjct: 660 GPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPR 719 Query: 979 G-PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQ--------------EIQQYISEYMQ 1023 G P G+ SGP GPPG GPPG G+ ++ + E Sbjct: 720 GLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAP 779 Query: 1024 SDSIRSYLSGVQGPPGPPG---------PPGPVTTI--TGETFDYSELASHVVSYLRTSG 1072 L+G GPPGP G PPGP + G + E T Sbjct: 780 GKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE----------TGP 829 Query: 1073 YGVSLFSSSISSEDILAVL-QRDDVRQYLRQYLMGPRGP---PGPPGASGDGSLLSLDYA 1128 G + F+ ++ ++ + Q GP+GP PGP G +G A Sbjct: 830 PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGA 889 Query: 1129 ELSSRILSYMSSSGISIGLPGP---PGPPGLPGTSYEELLSLLRGSEFR-------GIVG 1178 + + ++G +G PG PGPPG PG S ++ RG G+ G Sbjct: 890 QGPPGATGFPGAAG-RVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQG 948 Query: 1179 PPGPPGPPGIPGNVWSSISV-----EDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSG 1233 P GPPG G PG+ S + + L+ GL G G PG PGP G PG G Sbjct: 949 PAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQG 1008 Query: 1234 ALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSS 1293 A VGPPG GP G PG D R + Sbjct: 1009 APGASGDRGPPG-----------------PVGPPGLTGPAGEPGREGSPGADGPPGRDGA 1051 Query: 1294 SSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEG 1353 + RG + + G GS G G G+ GDRG G GP G G A Sbjct: 1052 AGVKGD---RGETGAVGAPGAPGPPGSPGPAGPTGKQ-GDRGEAGAQ-GPMGPSGPAGAR 1106 Query: 1354 GMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYT-VQGPPGQPGPQGPPGI 1412 G+ G AG+ +GL +T +QG PG PGP G G Sbjct: 1107 GIQGPQGPRGDKGEAGEPG-------------ERGLKGHRGFTGLQGLPGPPGPSGDQGA 1153 Query: 1413 SKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGP---------KGDRGPAGPPGH 1463 S G + GP G+ G G PGP G+ GPAGPPG+ Sbjct: 1154 SGPAGPSGPRGPP--------GPV-GPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGN 1204 Query: 1464 PGPPGPRGHKG 1474 PGPPGP G G Sbjct: 1205 PGPPGPPGPPG 1215 Score = 459 bits (1180), Expect = e-128 Identities = 331/926 (35%), Positives = 398/926 (42%), Gaps = 142/926 (15%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLG---HPGPQGPKGQKGSVGDPGM------ 616 +G GP G G G +G RG PGTPG PGP G +PG G G KGS G PG+ Sbjct: 374 KGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 433 Query: 617 ---EGPMGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGP---KGS 669 GP G +G GP+GP+G+ G PG +G KGE+G GEPGP GP G PG G +G+ Sbjct: 434 PGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGA 493 Query: 670 SGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGL 729 G PG GP GP G +G G G PG G GP G PG +G G GP+G G+PG G Sbjct: 494 RGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGE 553 Query: 730 PGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGL 789 PG G G G G AGP G GP G G G PG PPGP G G+PG+ G GP+G Sbjct: 554 PGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPG---PPGPQGARGQPGVMGFPGPKGA 610 Query: 790 PGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGH 849 G PG+ G KG PGAPG + +PG G GA GPPGP G G G G PG Sbjct: 611 NGEPGKAGEKGLPGAPG---------LRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGP 661 Query: 850 QEVLNLQGPPGPPGPRGPPG----------PSIPGPPGPRGPPGE-------GLPGPPGP 892 L GPPGPPG G PG P + GP G RG PGE GL GP G Sbjct: 662 SGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGL 721 Query: 893 PGSFLSNSETFLSGPPGPPGPPGPKGDQGPPG---------PRGHQGEQGLPGFSTSGSS 943 PG+ ++ SGP GPPG GP G QG PG P+G +G+ G G + Sbjct: 722 PGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGK 781 Query: 944 SFGLNLQGPPGPPGPQGPKGDKGD---PGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGP 1000 G L GP GPPGP G G+KG+ PG G+ G P E G + GPPGP G Sbjct: 782 DGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET------GPPGPAGF 835 Query: 1001 PGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSEL 1060 GPPG+ G + +Q E Q + G QGP G PGP GP T +TG Sbjct: 836 AGPPGADGQPGAKGEQ--GEAGQKGDAGA--PGPQGPSGAPGPQGP-TGVTGPKGARGAQ 890 Query: 1061 ASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASG-D 1119 + + V S+ G GPPGPPG SG D Sbjct: 891 GPPGATGFPGAAGRVGPPGSN------------------------GNPGPPGPPGPSGKD 926 Query: 1120 GSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGP 1179 G +R S GL GP GPPG G ++ G G Sbjct: 927 GPK--------GARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDD-----------GPSGA 967 Query: 1180 PGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPG------------PPGPRG 1227 GPPGP G+ G + L G +PGP G PG PPGP G Sbjct: 968 EGPPGPQGLAGQR----GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVG 1023 Query: 1228 PPGVSGALATYAAENSDSFRS----ELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLS 1283 PPG++G E S + + + + VG PG PGP G PG + Sbjct: 1024 PPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTG 1083 Query: 1284 TDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAA--GDRGPYGTD- 1340 + S G + + + G G G G GE G RG G Sbjct: 1084 KQGDRGEAGAQGPMGPS---GPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQG 1140 Query: 1341 ----IGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYT 1396 GP G GA+ G G +G N + + R + Sbjct: 1141 LPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAG 1200 Query: 1397 VQGPPGQPGPQGPPGISKVFSAYSNV 1422 G PG PGP GPPG SA++ + Sbjct: 1201 PPGNPGPPGPPGPPGPGIDMSAFAGL 1226 Score = 452 bits (1163), Expect = e-126 Identities = 333/963 (34%), Positives = 391/963 (40%), Gaps = 204/963 (21%) Query: 576 GSPGPKGDRGFPGT-PGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGE 634 G PGPKG +G PG I GP G PGPQGP G++G GD G +G +G GPRG Sbjct: 98 GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGD------RGDKGEKGAPGPRGR 151 Query: 635 AGPPGSGEKGERGAAGEPGPHGPPGVPGS------------------------VGPKGSS 670 G PG+ G G G PGP GPPG+ G+ +GP G Sbjct: 152 DGEPGT--PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPR 209 Query: 671 GSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLP 730 G PGP G PGP G QG GE G PGV G GP GPPGP G G+ G G G+ G RG P Sbjct: 210 GPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPP 269 Query: 731 GAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLP 790 G G G G G G GH+G G G G G G G SG PG+ G GP GP+GLP Sbjct: 270 GPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP 329 Query: 791 GTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGP---PGPPGAPGPAGPAGLP 847 G GR G G GA G ++G PGP GPPG +GP PG PGAPG G AG Sbjct: 330 GERGRTGPAGAAGARG----NDGQ-----PGPAGPPGPVGPAGGPGFPGAPGAKGEAGPT 380 Query: 848 GHQEVLNLQGPPGPPGPRGPPG-PSIPGPPGPRGPPG-EGLPGPPGPPGSFLSNSETFLS 905 G +GP G GPRG PG P PGP G G PG +G+PG G G+ Sbjct: 381 G------ARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA---PGIAGAP 431 Query: 906 GPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDK 965 G PGP GPPGP+G GP GP+G GE G+ GF GP G PGP G +G + Sbjct: 432 GFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 491 Query: 966 GDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSD 1025 G G PG +G P E G+ G G GP G PG SG + Sbjct: 492 GARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPK--------- 542 Query: 1026 SIRSYLSGVQGPPGPPGPPG--PVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSIS 1083 G G PG PG PG +TG D +G + S Sbjct: 543 -------GANGDPGRPGEPGLPGARGLTGRPGD--------------AGPQGKVGPSGAP 581 Query: 1084 SEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGI 1143 ED G GPPGP GA G ++ + ++ G Sbjct: 582 GED-------------------GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKG- 621 Query: 1144 SIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSS 1203 LPG PG GLPG E G GPPGP GP G G + Sbjct: 622 ---LPGAPGLRGLPGKDGET-----------GAAGPPGPAGPAGERGEQGAP-------- 659 Query: 1204 YLHTAGLSFIPGPPGPPGP---PGPRGPPGVSGALATYAAENSDSFRSELISY----LTS 1256 +G +PGPPGPPG PG +G PG +GA F E S L Sbjct: 660 --GPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQG 717 Query: 1257 P---------DVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSY 1307 P D GP GPPG QGPPG + + +G Sbjct: 718 PRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEG 777 Query: 1308 SSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADF 1367 + G G G +G G G A G++G ++GP G G+A G G Sbjct: 778 APGKDGGRGLTGPIGPPGPAG-ANGEKG----EVGPPGPAGSAGARGAPGERGET----- 827 Query: 1368 AGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLM 1427 GPPG G GPPG A Sbjct: 828 -------------------------------GPPGPAGFAGPPGADGQPGAKGE------ 850 Query: 1428 DFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGR 1487 QG GQKG+ G PGP+G G GP G G GP+G +G +G G + G Sbjct: 851 ---------QGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGA 901 Query: 1488 RRR 1490 R Sbjct: 902 AGR 904 Score = 444 bits (1143), Expect = e-124 Identities = 328/932 (35%), Positives = 381/932 (40%), Gaps = 210/932 (22%) Query: 562 NGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMG 621 N G PG KG G+PG G GFPG G PGP G GP GPKGQ G G G +G G Sbjct: 409 NPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQG 468 Query: 622 QRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGS------------------ 663 +G GP GP+G GP +GE+G+RGA GEPG GP G PG Sbjct: 469 PKGEPGPAGPQGAPGP--AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGP 526 Query: 664 ------------VGPKGSSGSPGPQGPPGPVGLQGL---------RGEVGLPGVKGDKGP 702 GPKG++G PG G PG G +GL +G+VG G G+ G Sbjct: 527 KGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGR 586 Query: 703 MGPPGPK------------------GDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGP 744 GPPGP+ G+ G+ G +GL G PG+RGLPG GE GA G GP Sbjct: 587 PGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP 646 Query: 745 AGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKP---GLTGPQGPQGLPGTPGRPGIKGE 801 AGP G +G +G G +G G+ GPPGP G+ GKP G+ G G GL G G G GE Sbjct: 647 AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 706 Query: 802 PGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGP--- 858 G+PG + PG GP GA GP GPPGA GP G G+PG + + GP Sbjct: 707 RGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGD 766 Query: 859 ------------PGPPGPRGPPGPSIPGPPGPRGPPGE-GLPGPPGPPGSFLSN---SET 902 PG G RG GP GPPGP G GE G GPPGP GS + E Sbjct: 767 RGDVGEKGPEGAPGKDGGRGLTGPI--GPPGPAGANGEKGEVGPPGPAGSAGARGAPGER 824 Query: 903 FLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPK 962 +GPPGP G GP G G PG +G QGE G G + + GP GP G GPK Sbjct: 825 GETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPK 884 Query: 963 GDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYM 1022 G +G G PGA G P G + +G PGPPGPPGP G G Sbjct: 885 GARGAQGPPGATGFPGAAGRVGPPGS---NGNPGPPGPPGPSGKDGPKG----------A 931 Query: 1023 QSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSI 1082 + DS +G G GP GPPG GE D + G Sbjct: 932 RGDSGPPGRAGEPGLQGPAGPPGE----KGEPGDDGP----------SGAEGPPGPQGLA 977 Query: 1083 SSEDILAVLQRDDVRQYLRQYLMGPRGPP---GPPGASGDGSLLSLDYAELSSRILSYMS 1139 I+ + + R + L GP G P G PGASGD Sbjct: 978 GQRGIVGLPGQRGERGF--PGLPGPSGEPGKQGAPGASGDR------------------- 1016 Query: 1140 SSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVE 1199 G PGP GPPGL G + E G G PG GPPG G Sbjct: 1017 ------GPPGPVGPPGLTGPAGEP-----------GREGSPGADGPPGRDG-------AA 1052 Query: 1200 DLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDV 1259 + G PG PGPPG PGP GP G G A+ P Sbjct: 1053 GVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQ--------------GPMG 1098 Query: 1260 RSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAG 1319 S G G GPQGP GD RG + + G +G Sbjct: 1099 PSGPAGARGIQGPQGPRGDK---------GEAGEPGERGLKGHRGFTGLQGLPGPPGPSG 1149 Query: 1320 SLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVR 1379 GA G G +G RGP G +GP G GA G G + G Sbjct: 1150 DQGASGPAG-PSGPRGPPG-PVGPSGKDGANGIPGPIGPPGPRGRSGETGP--------- 1198 Query: 1380 VSESMQRQGLLQGMAYTVQGPPGQPGPQGPPG 1411 GPPG PGP GPPG Sbjct: 1199 ------------------AGPPGNPGPPGPPG 1212 Score = 421 bits (1083), Expect = e-117 Identities = 302/790 (38%), Positives = 347/790 (43%), Gaps = 135/790 (17%) Query: 559 EQENGNLRGSPGPKGDMGSPGPKG---DRGFPGTPGIPGPLGHPGPQGPKG--------- 606 E+ RG PG G +G PG +G +RGFPG G+ GP G PG +GP G Sbjct: 487 EEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANG 546 Query: 607 QKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGS-GEKGERGAAGEPGPHGPPGVPGSVG 665 G G+PG+ G G GR G GP+G+ GP G+ GE G G G G G PGV G G Sbjct: 547 DPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPG 606 Query: 666 PKGSSGSPGPQGP---PGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTG 722 PKG++G PG G PG GL+GL G+ G G G GP GP G +G+QG GP G G Sbjct: 607 PKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQG 666 Query: 723 EPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQG------------------LTGMPG 764 PG G PG G+PG +G G AG G GPRGE+G L G PG Sbjct: 667 LPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG 726 Query: 765 IRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGI------------KGEPGAPGKIVTSE 812 GP G SG G PG GP G QG+PG G GI KG GAPGK + Sbjct: 727 TDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGK----D 782 Query: 813 GSSMLTVP-GPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS 871 G LT P GPPGP GA G G G PGPAG AG G GPPGP G GPPG Sbjct: 783 GGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGAD 842 Query: 872 IPGPPGPRGPPGE-------GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPG 924 G PG +G GE G PGP GP G+ GP GP G GPKG +G G Sbjct: 843 --GQPGAKGEQGEAGQKGDAGAPGPQGPSGA---------PGPQGPTGVTGPKGARGAQG 891 Query: 925 PRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGI-----PSG 979 P G G G G S+ GPPGP G GPKG +GD G PG G P+G Sbjct: 892 PPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAG 951 Query: 980 P----SEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSY----- 1030 P E G GPPGP G G G + GQ ++ Sbjct: 952 PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPG 1011 Query: 1031 LSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAV 1090 SG +GPPGP GPPG +T GE G S + D A Sbjct: 1012 ASGDRGPPGPVGPPG-LTGPAGE-----------------PGREGSPGADGPPGRDGAAG 1053 Query: 1091 LQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSL--DYAELSSRILSYMSSSGISIGLP 1148 ++ D +G G PGPPG+ G D E ++ S + G+ Sbjct: 1054 VKGDRG----ETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQ 1109 Query: 1149 GPPGPPGLPGTSYEELLSLLRGSE-FRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHT 1207 GP GP G G + E L+G F G+ G PGPPGP G Sbjct: 1110 GPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSG-------------------D 1150 Query: 1208 AGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPP 1267 G S GP GP GPPGP GP G GA R S T P GPP Sbjct: 1151 QGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGR--SGETGP------AGPP 1202 Query: 1268 GPPGPQGPPG 1277 G PGP GPPG Sbjct: 1203 GNPGPPGPPG 1212 Score = 419 bits (1078), Expect = e-117 Identities = 323/955 (33%), Positives = 368/955 (38%), Gaps = 181/955 (18%) Query: 627 GPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQG 686 G GP+G+ G PG + G GP GP G G GP+G G G +G PGP G G Sbjct: 98 GQPGPKGQKGEPGD----IKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDG 153 Query: 687 LRGEVGLPGVKGDKGPMGPP------------------------------GPKGDQGEKG 716 G G PG G GP GPP GP G +G G Sbjct: 154 EPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPG 213 Query: 717 PRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMP---GIRGPPGPSG 773 P G G G +G PG GEPG G MGP GP G G G+ G G P G RGPPGP G Sbjct: 214 PAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQG 273 Query: 774 DPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGP-- 831 G PG G G +G G PG G KGE GAPG V E S PG G PG MGP Sbjct: 274 ARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPG--VKGESGS----PGENGSPGPMGPRG 327 Query: 832 ----------------------PGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG 869 PGP G PGP GPAG PG +G GP G RGP G Sbjct: 328 LPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEG 387 Query: 870 -------PSIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQG 921 P PG PGP G G G G PG GS + G PGP GPPGP+G G Sbjct: 388 AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATG 447 Query: 922 PPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPS 981 P GP+G GE G+ GF GP G PGP G +G +G G PG +G P Sbjct: 448 PLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPG 507 Query: 982 EGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPP 1041 E G+ G G GP G PG SG + G G PG P Sbjct: 508 ERGAPGNRGFPGQDGLAGPKGAPGERGPSG----------------LAGPKGANGDPGRP 551 Query: 1042 GPPG--PVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQY 1099 G PG +TG D +G + S ED Sbjct: 552 GEPGLPGARGLTGRPGD--------------AGPQGKVGPSGAPGED------------- 584 Query: 1100 LRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGT 1159 G GPPGP GA G ++ + + GLPG PG GLPG Sbjct: 585 ------GRPGPPGPQGARGQPGVMGFP----GPKGANGEPGKAGEKGLPGAPGLRGLPGK 634 Query: 1160 SYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGP 1219 E G GPPGP GP G G + +G +PGPPGP Sbjct: 635 DGE-----------TGAAGPPGPAGPAGERGEQGAP----------GPSGFQGLPGPPGP 673 Query: 1220 P---GPPGPRGPPGVSGALATYAAENSDSFRSELIS----YLTSP---------DVRSFI 1263 P G PG +G PG +GA F E S L P D Sbjct: 674 PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGA 733 Query: 1264 VGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGA 1323 GP GPPG QGPPG + + +G + G G G +G Sbjct: 734 SGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGP 793 Query: 1324 GGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSES 1383 G G A G++G G GP G GA G G A FAG + E Sbjct: 794 PGPAG-ANGEKGEVGPP-GPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQ 851 Query: 1384 MQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQK 1443 + A QGP G PGPQGP G++ A F GPPG Sbjct: 852 GEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSN 911 Query: 1444 GEMGTP---------GPKGDRGPAGPPGHPGPP---GPRGHKGEKGDKGDQVYAG 1486 G G P GPKG RG +GPPG G P GP G GEKG+ GD +G Sbjct: 912 GNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSG 966 Score = 340 bits (873), Expect = 5e-93 Identities = 281/846 (33%), Positives = 341/846 (40%), Gaps = 130/846 (15%) Query: 698 GDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQ 757 G+ P+ P G+ GP+G GEPG + VG KG GP GP G QGPRG++ Sbjct: 83 GECCPICPTDLATASGQPGPKGQKGEPG--DIKDIVGP---KGPPGPQGPAGEQGPRGDR 137 Query: 758 GLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSML 817 G G G GP G G+PG PG GP GP G PG PG G A G + G+ + Sbjct: 138 GDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLG 197 Query: 818 TVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG-------P 870 + GP GP G GPPGP GAPGP G G PG + GP GP GP GPPG Sbjct: 198 VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEA 257 Query: 871 SIPGPPGPRGPPG----EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPP--- 923 PG G RGPPG G PG PG PG L G G G PG KG+ G P Sbjct: 258 GKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN 317 Query: 924 ------GPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIP 977 GPRG GE+G G + + + GP GPPGP GP G G PG PGA G Sbjct: 318 GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKG-E 376 Query: 978 SGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGP 1037 +GP+ G+ GP G PG PG PG +SG I S ++G G Sbjct: 377 AGPT--GARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG-IAGAPGF 433 Query: 1038 PGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVR 1097 PGP GPPGP G T +T G++ F Sbjct: 434 PGPRGPPGP----QGATGPLGPKG-------QTGEPGIAGFKGE---------------- 466 Query: 1098 QYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLP 1157 GP+G PGP G G E R IG PG G PG Sbjct: 467 -------QGPKGEPGPAGPQGAPG----PAGEEGKRGARGEPGGVGPIGPPGERGAPGNR 515 Query: 1158 GTSYEELLSLLRGSEFR----GIVGP------PGPPGPPGIPGNVWSSISVEDL--SSYL 1205 G ++ L+ +G+ G+ GP PG PG PG+PG + D + Sbjct: 516 GFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKV 575 Query: 1206 HTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSEL-------ISYLTSPD 1258 +G G PGPPGP G RG PGV G A E + L D Sbjct: 576 GPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKD 635 Query: 1259 VRSFIVGPPGPPGP------QGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMS 1312 + GPPGP GP QG PG S G + + + Sbjct: 636 GETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLV 695 Query: 1313 TGGGGAGSLGAGGAFGEAAGDRGPY------GTD-----IGPGGGYGAAAEGGMYAGNGG 1361 G G G G+ G A G +GP GTD GP G GA G+ G Sbjct: 696 GPRGERGFPGERGSPG-AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGE 754 Query: 1362 LLGADFAGDL-DYNELAVRVSESMQRQGLLQGMAYTVQGPP------GQPGPQGPPGISK 1414 A AG D ++ + E + +G+ + GPP G+ G GPPG + Sbjct: 755 RGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI-GPPGPAGANGEKGEVGPPGPAG 813 Query: 1415 VFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKG 1474 A +G PG++GE G PGP G GP G G PG G +G G Sbjct: 814 SAGA------------------RGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAG 855 Query: 1475 EKGDKG 1480 +KGD G Sbjct: 856 QKGDAG 861 Score = 197 bits (500), Expect = 8e-50 Identities = 186/616 (30%), Positives = 224/616 (36%), Gaps = 135/616 (21%) Query: 889 PPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGP----PGPRGHQGEQGLPGFSTSGSSS 944 P P G T L+ G PGP G KG+ G GP+G G Sbjct: 78 PEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGP------------- 124 Query: 945 FGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPP 1004 QGP G GP+G +GDKG+ G PG G P G+ GPPGPPGPPGPP Sbjct: 125 -----QGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGN------PGPPGPPGPPGPP 173 Query: 1005 GSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHV 1064 G + ++ E + + G GP GP GPPGP + F Sbjct: 174 GLGGNFAAQMAGGFDEKAGGAQL-GVMQGPMGPMGPRGPPGPAGAPGPQGF--------- 223 Query: 1065 VSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLS 1124 G +S MGPRGPPGPPG GD Sbjct: 224 ------QGNPGEPGEPGVSGP-------------------MGPRGPPGPPGKPGDDGEAG 258 Query: 1125 LDYAELSSRILSYMSSSGISIGLPGPPGP------PGLPGTSYEELLSLLRG-SEFRGIV 1177 + G G PG PG PGL G E ++G S G Sbjct: 259 KPGKAGERGPPGPQGARGFP-GTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN 317 Query: 1178 GPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALAT 1237 G PGP GP G+PG + + G PGP GPPGP GP G PG GA Sbjct: 318 GSPGPMGPRGLPGERGRT----GPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGA 373 Query: 1238 YAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSH 1297 R P+ G PG PG GP G S TD G+ S+ Sbjct: 374 KGEAGPTGAR--------GPEGAQGPRGEPGTPGSPGPAGASGNPGTDG--IPGAKGSAG 423 Query: 1298 SSSVRRGSSYSSSMSTGG--GGAGSLGAGGAFGEAA-----GDRGPYGTDIGPGGGYGAA 1350 + + + G G G LG G GE G++GP G + GP G GA Sbjct: 424 APGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG-EPGPAGPQGAP 482 Query: 1351 AEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPP 1410 AG G GA +G G+ GP G PG +G P Sbjct: 483 GP----AGEEGKRGA---------------------RGEPGGV-----GPIGPPGERGAP 512 Query: 1411 GISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPR 1470 G ++ F + +G PG++G G GPKG G G PG PG PG R Sbjct: 513 G-NRGFPGQDGLAGP-----------KGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 560 Query: 1471 GHKGEKGDKGDQVYAG 1486 G G GD G Q G Sbjct: 561 GLTGRPGDAGPQGKVG 576 Score = 196 bits (499), Expect = 1e-49 Identities = 185/614 (30%), Positives = 224/614 (36%), Gaps = 106/614 (17%) Query: 912 GPPGPKGDQGPPGP-RGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGV 970 G PGPKG +G PG + G +G PG QGP G GP+G +GDKG+ G Sbjct: 98 GQPGPKGQKGEPGDIKDIVGPKGPPG------------PQGPAGEQGPRGDRGDKGEKGA 145 Query: 971 PGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSY 1030 PG G P G+ GPPGPPGPPGPPG + ++ E + Sbjct: 146 PGPRGRDGEPGTPGNP------GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQL-GV 198 Query: 1031 LSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAV 1090 + G GP GP GPPGP + F G +S Sbjct: 199 MQGPMGPMGPRGPPGPAGAPGPQGFQ---------------GNPGEPGEPGVSGP----- 238 Query: 1091 LQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGP 1150 MGPRGPPGPPG GD + G G PG Sbjct: 239 --------------MGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFP-GTPGL 283 Query: 1151 PGP------PGLPGTSYEELLSLLRG-SEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSS 1203 PG PGL G E ++G S G G PGP GP G+PG + + Sbjct: 284 PGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRT----GPAG 339 Query: 1204 YLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFI 1263 G PGP GPPGP GP G PG GA R P+ Sbjct: 340 AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARG--------PEGAQGP 391 Query: 1264 VGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGG--GGAGSL 1321 G PG PG GP G S TD G+ S+ + + + G G G L Sbjct: 392 RGEPGTPGSPGPAGASGNPGTDGIP--GAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL 449 Query: 1322 GAGGAFGEAA-----GDRGPYGTD--IGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYN 1374 G G GE G++GP G GP G G A E G G G G Sbjct: 450 GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPP--G 507 Query: 1375 ELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYG 1434 E + Q G+A GP G PG +GP G++ A + Sbjct: 508 ERGAPGNRGFPGQ---DGLA----GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 560 Query: 1435 AIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGP------------PGPRGHKGEKGDKGDQ 1482 + G PG G G GP G G G PG PGP PGP+G GE G G++ Sbjct: 561 GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEK 620 Query: 1483 VYAGRRRRRSIAVK 1496 G R + K Sbjct: 621 GLPGAPGLRGLPGK 634 Score = 109 bits (272), Expect = 2e-23 Identities = 64/153 (41%), Positives = 75/153 (49%), Gaps = 27/153 (17%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 ++G GP+GD G G G+RG G G G G PGP GP G +G+ G GP G RG Sbjct: 1108 IQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGA---SGPAGPSGPRG 1164 Query: 625 REGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGL 684 GP+GP SG+ G G G GP GP G G GP G G+PGP GPPGP G Sbjct: 1165 PPGPVGP--------SGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG- 1215 Query: 685 QGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGP 717 PG+ D GP+ EKGP Sbjct: 1216 ---------PGI--DMSAFAGLGPR----EKGP 1233 Score = 84.3 bits (207), Expect = 8e-16 Identities = 82/280 (29%), Positives = 97/280 (34%), Gaps = 96/280 (34%) Query: 1218 GPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPG 1277 G PGP G +G PG D++ IVGP GPPGPQGP G Sbjct: 98 GQPGPKGQKGEPG---------------------------DIKD-IVGPKGPPGPQGPAG 129 Query: 1278 DSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPY 1337 + RG RG G G+ G G GE P Sbjct: 130 EQG--------PRGD----------RGDK---------GEKGAPGPRGRDGEPGTPGNP- 161 Query: 1338 GTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTV 1397 GP G G G+ GG A AG D ++ G++QG + Sbjct: 162 ----GPPGPPGPPGPPGL----GGNFAAQMAGGFDEKAGGAQL-------GVMQGPMGPM 206 Query: 1398 QGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGP 1457 GP G PGP G PG QG G GE G PG G GP Sbjct: 207 -GPRGPPGPAGAPGP------------------------QGFQGNPGEPGEPGVSGPMGP 241 Query: 1458 AGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 GPPG PG PG G G+ G G++ G + R P Sbjct: 242 RGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTP 281 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 487 bits (1254), Expect = e-137 Identities = 359/1032 (34%), Positives = 416/1032 (40%), Gaps = 184/1032 (17%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPG---------- 615 RG G KG+ G+PGP+G G PGTPG PGP G PGP GP G G+ Sbjct: 65 RGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGG 124 Query: 616 -----MEGPMGQRGREGPMGPRGEAGPPG----SGEKGERGAAGEPGPHGPPGVPGSVGP 666 M+GPMG G GP GP G GP G GE GE G +G GP GPPG PG G Sbjct: 125 AQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 184 Query: 667 KGSSGSP---GPQGPPGPVGLQGLRGEVGLPGVKGD------------------KGPMGP 705 G +G P G +GPPGP G +G G GLPGVKG KG G Sbjct: 185 DGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 244 Query: 706 PGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGI 765 PG G G GPRGL GE G G GA G G G GPAGP G GP G G G PG Sbjct: 245 PGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGA 304 Query: 766 RGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGP 825 +G GP+G G G GP+G G PG+PG G G PG G + + G PG Sbjct: 305 KGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 364 Query: 826 PGAMGPPGPPGAPGPAGPAGLPGHQEVLNL---QGP---PGPPGPRGPPGPS-------- 871 PG GPPGP GA GP GP G G + QGP PGP GP+G PGP+ Sbjct: 365 PGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGA 424 Query: 872 --IPGPPGPRGPPGE-------------GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGP 916 PG GP GPPGE GL GP G PG + L+GP G G PG Sbjct: 425 RGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG---ERGPSGLAGPKGANGDPGR 481 Query: 917 KGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQ------------GPKGD 964 G+ G PG RG G G G S G PGPPGPQ GPKG Sbjct: 482 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGA 541 Query: 965 KGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQS 1024 G+PG G G+P P G +G GPPGP GP G G Sbjct: 542 NGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGP--------- 592 Query: 1025 DSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISS 1084 SG QG PGPPGPPG + A +V G+ S Sbjct: 593 -------SGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG--- 642 Query: 1085 EDILAVLQRDDVRQYLRQYLMGPR---------------GPPGPPGASGDGSLLSLDYAE 1129 Q L GPR GP GPPGA G L + Sbjct: 643 ----------------AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGER 686 Query: 1130 LSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIP 1189 ++ I G +G GP G PG G RG+ GP GPPGP G Sbjct: 687 GAAGIAGPKGDRG-DVGEKGPEGAPGKDGG--------------RGLTGPIGPPGPAGAN 731 Query: 1190 GNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSE 1249 G + + G G GPPGP G GPPG G + + + Sbjct: 732 GEK-GEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGD 790 Query: 1250 L-------ISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVR 1302 S P + + GP G G QGPPG + + R S+ + Sbjct: 791 AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGAT---GFPGAAGRVGPPGSNGNPGP 847 Query: 1303 RGSSYSSSMSTGGGGAGSLGAGGAFGEAA--GDRGPYGT-----DIGPGGGYGAAAEGGM 1355 G S G G G G GE G GP G D GP G G G+ Sbjct: 848 PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 907 Query: 1356 YAGNGGLLG-ADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISK 1414 AG G++G G+ + L E +QG A G G PGP GPPG++ Sbjct: 908 -AGQRGIVGLPGQRGERGFPGLPGPSGEP-GKQG-----APGASGDRGPPGPVGPPGLTG 960 Query: 1415 VFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKG 1474 + D GPPG+ G G G +G+ G G PG PGPPG G G Sbjct: 961 PAGEPGREGSPGAD---------GPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAG 1011 Query: 1475 EKGDKGDQVYAG 1486 G +GD+ AG Sbjct: 1012 PTGKQGDRGEAG 1023 Score = 483 bits (1242), Expect = e-136 Identities = 365/1021 (35%), Positives = 424/1021 (41%), Gaps = 203/1021 (19%) Query: 560 QENGNLRGSPGPKGDM---GSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGM 616 Q N G PG G M G PGP G G G G PG G GP GP+G +G G PG+ Sbjct: 155 QGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGL 214 Query: 617 EGPMGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVP---------GSVGP 666 G G RG G G +GEAG PG GE G G G PGP GP G+P G+ G Sbjct: 215 PGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGA 274 Query: 667 KGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEK---------GP 717 +G+ G PGP GPPGPVG G G G PG KG+ GP G GP+G QG + GP Sbjct: 275 RGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGP 334 Query: 718 RGLTGEPGMRGLPGA---------VGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGP 768 G +G PG G+PGA G PG G GP GP G GP G +G TG PGI G Sbjct: 335 AGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGF 394 Query: 769 PGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKI-------------------- 808 G G G+PG GPQG G G G+ G +GEPG G I Sbjct: 395 KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGL 454 Query: 809 ------VTSEGSSMLTVP-GPPGPPGAMGPPGPPGA------PGPAGPAGLPGHQEVLNL 855 G S L P G G PG G PG PGA PG AGP G G Sbjct: 455 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGE 514 Query: 856 QGPPGPPGPRGPPG-PSIPGPPGPRGPPGE-------GLPGPPGPPGSFLSNSETFLSGP 907 G PGPPGP+G G P + G PGP+G GE GLPG PG G + ET +GP Sbjct: 515 DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP 574 Query: 908 PGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGD 967 PGP GP G +G+QG PGP G QG G PG G + G G PG GP+G++G Sbjct: 575 PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 634 Query: 968 P---GVPGALGI--PSG-PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEY 1021 P G PGA G+ P G P G+ SGP GPPG GPPG G+ I+ Sbjct: 635 PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAG- 693 Query: 1022 MQSDSIRSYLSGVQGPP---------GPPGPPGPVTTITGETFDYSELASHVVSYLRTSG 1072 + D G +G P GP GPPGP G + E+ G Sbjct: 694 PKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGP----AGANGEKGEVG--------PPG 741 Query: 1073 YGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSS 1132 S + E G GPPGP G +G A+ Sbjct: 742 PAGSAGARGAPGE-------------------RGETGPPGPAGFAGPPGADGQPGAKGEQ 782 Query: 1133 RILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNV 1192 + G PGP GP G PG ++ +G+ RG GPPG G PG G V Sbjct: 783 GEAGQKGDA----GAPGPQGPSGAPGPQGPTGVTGPKGA--RGAQGPPGATGFPGAAGRV 836 Query: 1193 WSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELIS 1252 G + PGPPGPPGP G GP G G + Sbjct: 837 -------------GPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ----- 878 Query: 1253 YLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSV-----RRGSSY 1307 GP GPPG +G PGD + A G + + +RG Sbjct: 879 ------------GPAGPPGEKGEPGDDG--PSGAEGPPGPQGLAGQRGIVGLPGQRGERG 924 Query: 1308 SSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADF 1367 + G G GA G A+GDRGP G +GP G G A E G G GAD Sbjct: 925 FPGLPGPSGEPGKQGAPG----ASGDRGPPG-PVGPPGLTGPAGE----PGREGSPGADG 975 Query: 1368 AGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLM 1427 D A V G + A GPPG PGP GP Sbjct: 976 PPGRDG---AAGVKGDRGETGAVG--APGAPGPPGSPGPAGP------------------ 1012 Query: 1428 DFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGR 1487 G G +GE G GP G GPAG G GP GPRG KGE G+ G++ G Sbjct: 1013 ---------TGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGH 1063 Query: 1488 R 1488 R Sbjct: 1064 R 1064 Score = 477 bits (1227), Expect = e-134 Identities = 366/1029 (35%), Positives = 426/1029 (41%), Gaps = 239/1029 (23%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFP---------------GTPGIPGPLGHPGPQGPKGQKG 609 ++G G G+ GSPGP G RG P G G PGP G PGP GP G G Sbjct: 238 VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPG 297 Query: 610 SVGDPGME---GPMGQRGREGPMGPRGEAGPPGS----------------------GEKG 644 G PG + GP G RG EG GPRGE G PGS G G Sbjct: 298 FPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG 357 Query: 645 ERGAAGEPGPHGPP---GVPGSVGPKGSSGSP---------GPQGPPGPVGLQGLRGEVG 692 GA G PGP GPP G G +GPKG +G P GP+G PGP G QG G G Sbjct: 358 IAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAG 417 Query: 693 LPGVKGDK------GPMGPP------------------GPKGDQGEKGPRGLTGEPGMRG 728 G +G + GP+GPP GPKG GE+GP GL G G G Sbjct: 418 EEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANG 477 Query: 729 LPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMP---GIRGPPGPSGDPGKPGLTGPQG 785 PG GEPG GA G G G GP+G+ G +G P G GPPGP G G+PG+ G G Sbjct: 478 DPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPG 537 Query: 786 PQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAG 845 P+G G PG+ G KG PGAPG + +PG G GA GPPGP G G G G Sbjct: 538 PKGANGEPGKAGEKGLPGAPG---------LRGLPGKDGETGAAGPPGPAGPAGERGEQG 588 Query: 846 LPGHQEVLNLQGPPGPPGPRGPPG----------PSIPGPPGPRGPPGE-------GLPG 888 PG L GPPGPPG G PG P + GP G RG PGE GL G Sbjct: 589 APGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQG 648 Query: 889 PPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPP---------GPRGHQGEQGLPGFST 939 P G PG+ ++ SGP GPPG GP G QG P GP+G +G+ G G Sbjct: 649 PRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEG 708 Query: 940 SGSSSFGLNLQGPPGPPGPQGPKGDKGD---PGVPGALGIPSGPSEGGSSSTMYVSGPPG 996 + G L GP GPPGP G G+KG+ PG G+ G P E G +GPPG Sbjct: 709 APGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE------TGPPG 762 Query: 997 PPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFD 1056 P G GPPG+ G + +Q E Q + G QGP G PGP GP T +TG Sbjct: 763 PAGFAGPPGADGQPGAKGEQ--GEAGQKGDAGA--PGPQGPSGAPGPQGP-TGVTGPKGA 817 Query: 1057 YSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGA 1116 + + V S+ G GPPGPPG Sbjct: 818 RGAQGPPGATGFPGAAGRVGPPGSN------------------------GNPGPPGPPGP 853 Query: 1117 SG-DGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRG 1175 SG DG +R S GL GP GPPG G ++ G Sbjct: 854 SGKDG--------PKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDD-----------G 894 Query: 1176 IVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGAL 1235 G GPPGP G+ G + G PG PGP G PG +G PG SG Sbjct: 895 PSGAEGPPGPQGLAGQ-------RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDR 947 Query: 1236 ATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSS 1295 VGPPG GP G PG D R ++ Sbjct: 948 GPPGP-----------------------VGPPGLTGPAGEPGREGSPGADGPPGRDGAAG 984 Query: 1296 SHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGM 1355 RG + + G GS G G G+ GDRG G GP G G A G+ Sbjct: 985 VKGD---RGETGAVGAPGAPGPPGSPGPAGPTGK-QGDRGEAGAQ-GPMGPSGPAGARGI 1039 Query: 1356 YAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYT-VQGPPGQPGPQGPPGISK 1414 G AG+ +GL +T +QG PG PGP G G S Sbjct: 1040 QGPQGPRGDKGEAGE-------------PGERGLKGHRGFTGLQGLPGPPGPSGDQGASG 1086 Query: 1415 VFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGP---------KGDRGPAGPPGHPG 1465 A G + GP G+ G G PGP G+ GPAGPPG+PG Sbjct: 1087 --------PAGPSGPRGPPGPV-GPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG 1137 Query: 1466 PPGPRGHKG 1474 PPGP G G Sbjct: 1138 PPGPPGPPG 1146 Score = 459 bits (1180), Expect = e-128 Identities = 331/926 (35%), Positives = 398/926 (42%), Gaps = 142/926 (15%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLG---HPGPQGPKGQKGSVGDPGM------ 616 +G GP G G G +G RG PGTPG PGP G +PG G G KGS G PG+ Sbjct: 305 KGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 364 Query: 617 ---EGPMGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGP---KGS 669 GP G +G GP+GP+G+ G PG +G KGE+G GEPGP GP G PG G +G+ Sbjct: 365 PGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGA 424 Query: 670 SGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGL 729 G PG GP GP G +G G G PG G GP G PG +G G GP+G G+PG G Sbjct: 425 RGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGE 484 Query: 730 PGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGL 789 PG G G G G AGP G GP G G G PG PPGP G G+PG+ G GP+G Sbjct: 485 PGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPG---PPGPQGARGQPGVMGFPGPKGA 541 Query: 790 PGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGH 849 G PG+ G KG PGAPG + +PG G GA GPPGP G G G G PG Sbjct: 542 NGEPGKAGEKGLPGAPG---------LRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGP 592 Query: 850 QEVLNLQGPPGPPGPRGPPG----------PSIPGPPGPRGPPGE-------GLPGPPGP 892 L GPPGPPG G PG P + GP G RG PGE GL GP G Sbjct: 593 SGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGL 652 Query: 893 PGSFLSNSETFLSGPPGPPGPPGPKGDQGPPG---------PRGHQGEQGLPGFSTSGSS 943 PG+ ++ SGP GPPG GP G QG PG P+G +G+ G G + Sbjct: 653 PGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGK 712 Query: 944 SFGLNLQGPPGPPGPQGPKGDKGD---PGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGP 1000 G L GP GPPGP G G+KG+ PG G+ G P E G + GPPGP G Sbjct: 713 DGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET------GPPGPAGF 766 Query: 1001 PGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSEL 1060 GPPG+ G + +Q E Q + G QGP G PGP GP T +TG Sbjct: 767 AGPPGADGQPGAKGEQ--GEAGQKGDAGA--PGPQGPSGAPGPQGP-TGVTGPKGARGAQ 821 Query: 1061 ASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASG-D 1119 + + V S+ G GPPGPPG SG D Sbjct: 822 GPPGATGFPGAAGRVGPPGSN------------------------GNPGPPGPPGPSGKD 857 Query: 1120 GSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGP 1179 G +R S GL GP GPPG G ++ G G Sbjct: 858 GPK--------GARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDD-----------GPSGA 898 Query: 1180 PGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPG------------PPGPRG 1227 GPPGP G+ G + L G +PGP G PG PPGP G Sbjct: 899 EGPPGPQGLAGQR----GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVG 954 Query: 1228 PPGVSGALATYAAENSDSFRS----ELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLS 1283 PPG++G E S + + + + VG PG PGP G PG + Sbjct: 955 PPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTG 1014 Query: 1284 TDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAA--GDRGPYGTD- 1340 + S G + + + G G G G GE G RG G Sbjct: 1015 KQGDRGEAGAQGPMGPS---GPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQG 1071 Query: 1341 ----IGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYT 1396 GP G GA+ G G +G N + + R + Sbjct: 1072 LPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAG 1131 Query: 1397 VQGPPGQPGPQGPPGISKVFSAYSNV 1422 G PG PGP GPPG SA++ + Sbjct: 1132 PPGNPGPPGPPGPPGPGIDMSAFAGL 1157 Score = 452 bits (1162), Expect = e-126 Identities = 333/965 (34%), Positives = 392/965 (40%), Gaps = 204/965 (21%) Query: 574 DMGSPGPKGDRGFPGT-PGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPR 632 D+ PGPKG +G PG I GP G PGPQGP G++G GD G +G +G GPR Sbjct: 27 DVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGD------RGDKGEKGAPGPR 80 Query: 633 GEAGPPGSGEKGERGAAGEPGPHGPPGVPGS------------------------VGPKG 668 G G PG+ G G G PGP GPPG+ G+ +GP G Sbjct: 81 GRDGEPGT--PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMG 138 Query: 669 SSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRG 728 G PGP G PGP G QG GE G PGV G GP GPPGP G G+ G G G+ G RG Sbjct: 139 PRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERG 198 Query: 729 LPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQG 788 PG G G G G G GH+G G G G G G G SG PG+ G GP GP+G Sbjct: 199 PPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRG 258 Query: 789 LPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGP---PGPPGAPGPAGPAG 845 LPG GR G G GA G ++G PGP GPPG +GP PG PGAPG G AG Sbjct: 259 LPGERGRTGPAGAAGARG----NDGQ-----PGPAGPPGPVGPAGGPGFPGAPGAKGEAG 309 Query: 846 LPGHQEVLNLQGPPGPPGPRGPPG-PSIPGPPGPRGPPG-EGLPGPPGPPGSFLSNSETF 903 G +GP G GPRG PG P PGP G G PG +G+PG G G+ Sbjct: 310 PTG------ARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA---PGIAG 360 Query: 904 LSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKG 963 G PGP GPPGP+G GP GP+G GE G+ GF GP G PGP G +G Sbjct: 361 APGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEG 420 Query: 964 DKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQ 1023 +G G PG +G P E G+ G G GP G PG SG + Sbjct: 421 KRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPK------- 473 Query: 1024 SDSIRSYLSGVQGPPGPPGPPG--PVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSS 1081 G G PG PG PG +TG D +G + S Sbjct: 474 ---------GANGDPGRPGEPGLPGARGLTGRPGD--------------AGPQGKVGPSG 510 Query: 1082 ISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSS 1141 ED G GPPGP GA G ++ + ++ Sbjct: 511 APGED-------------------GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEK 551 Query: 1142 GISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDL 1201 G LPG PG GLPG E G GPPGP GP G G + Sbjct: 552 G----LPGAPGLRGLPGKDGET-----------GAAGPPGPAGPAGERGEQGAP------ 590 Query: 1202 SSYLHTAGLSFIPGPPGPPGP---PGPRGPPGVSGALATYAAENSDSFRSELISY----L 1254 +G +PGPPGPPG PG +G PG +GA F E S L Sbjct: 591 ----GPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGL 646 Query: 1255 TSP---------DVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGS 1305 P D GP GPPG QGPPG + + +G Sbjct: 647 QGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGP 706 Query: 1306 SYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGA 1365 + G G G +G G G A G++G ++GP G G+A G G Sbjct: 707 EGAPGKDGGRGLTGPIGPPGPAG-ANGEKG----EVGPPGPAGSAGARGAPGERGET--- 758 Query: 1366 DFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTAD 1425 GPPG G GPPG A Sbjct: 759 ---------------------------------GPPGPAGFAGPPGADGQPGAKGE---- 781 Query: 1426 LMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYA 1485 QG GQKG+ G PGP+G G GP G G GP+G +G +G G + Sbjct: 782 -----------QGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP 830 Query: 1486 GRRRR 1490 G R Sbjct: 831 GAAGR 835 Score = 444 bits (1143), Expect = e-124 Identities = 328/932 (35%), Positives = 381/932 (40%), Gaps = 210/932 (22%) Query: 562 NGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMG 621 N G PG KG G+PG G GFPG G PGP G GP GPKGQ G G G +G G Sbjct: 340 NPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQG 399 Query: 622 QRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGS------------------ 663 +G GP GP+G GP +GE+G+RGA GEPG GP G PG Sbjct: 400 PKGEPGPAGPQGAPGP--AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGP 457 Query: 664 ------------VGPKGSSGSPGPQGPPGPVGLQGL---------RGEVGLPGVKGDKGP 702 GPKG++G PG G PG G +GL +G+VG G G+ G Sbjct: 458 KGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGR 517 Query: 703 MGPPGPK------------------GDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGP 744 GPPGP+ G+ G+ G +GL G PG+RGLPG GE GA G GP Sbjct: 518 PGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP 577 Query: 745 AGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKP---GLTGPQGPQGLPGTPGRPGIKGE 801 AGP G +G +G G +G G+ GPPGP G+ GKP G+ G G GL G G G GE Sbjct: 578 AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 637 Query: 802 PGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGP--- 858 G+PG + PG GP GA GP GPPGA GP G G+PG + + GP Sbjct: 638 RGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGD 697 Query: 859 ------------PGPPGPRGPPGPSIPGPPGPRGPPGE-GLPGPPGPPGSFLSN---SET 902 PG G RG GP GPPGP G GE G GPPGP GS + E Sbjct: 698 RGDVGEKGPEGAPGKDGGRGLTGPI--GPPGPAGANGEKGEVGPPGPAGSAGARGAPGER 755 Query: 903 FLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPK 962 +GPPGP G GP G G PG +G QGE G G + + GP GP G GPK Sbjct: 756 GETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPK 815 Query: 963 GDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYM 1022 G +G G PGA G P G + +G PGPPGPPGP G G Sbjct: 816 GARGAQGPPGATGFPGAAGRVGPPGS---NGNPGPPGPPGPSGKDGPKG----------A 862 Query: 1023 QSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSI 1082 + DS +G G GP GPPG GE D + G Sbjct: 863 RGDSGPPGRAGEPGLQGPAGPPGE----KGEPGDDGP----------SGAEGPPGPQGLA 908 Query: 1083 SSEDILAVLQRDDVRQYLRQYLMGPRGPP---GPPGASGDGSLLSLDYAELSSRILSYMS 1139 I+ + + R + L GP G P G PGASGD Sbjct: 909 GQRGIVGLPGQRGERGF--PGLPGPSGEPGKQGAPGASGDR------------------- 947 Query: 1140 SSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVE 1199 G PGP GPPGL G + E G G PG GPPG G Sbjct: 948 ------GPPGPVGPPGLTGPAGEP-----------GREGSPGADGPPGRDG-------AA 983 Query: 1200 DLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDV 1259 + G PG PGPPG PGP GP G G A+ P Sbjct: 984 GVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQ--------------GPMG 1029 Query: 1260 RSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAG 1319 S G G GPQGP GD RG + + G +G Sbjct: 1030 PSGPAGARGIQGPQGPRGDK---------GEAGEPGERGLKGHRGFTGLQGLPGPPGPSG 1080 Query: 1320 SLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVR 1379 GA G G +G RGP G +GP G GA G G + G Sbjct: 1081 DQGASGPAG-PSGPRGPPG-PVGPSGKDGANGIPGPIGPPGPRGRSGETGP--------- 1129 Query: 1380 VSESMQRQGLLQGMAYTVQGPPGQPGPQGPPG 1411 GPPG PGP GPPG Sbjct: 1130 ------------------AGPPGNPGPPGPPG 1143 Score = 421 bits (1083), Expect = e-117 Identities = 302/790 (38%), Positives = 347/790 (43%), Gaps = 135/790 (17%) Query: 559 EQENGNLRGSPGPKGDMGSPGPKG---DRGFPGTPGIPGPLGHPGPQGPKG--------- 606 E+ RG PG G +G PG +G +RGFPG G+ GP G PG +GP G Sbjct: 418 EEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANG 477 Query: 607 QKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGS-GEKGERGAAGEPGPHGPPGVPGSVG 665 G G+PG+ G G GR G GP+G+ GP G+ GE G G G G G PGV G G Sbjct: 478 DPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPG 537 Query: 666 PKGSSGSPGPQGP---PGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTG 722 PKG++G PG G PG GL+GL G+ G G G GP GP G +G+QG GP G G Sbjct: 538 PKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQG 597 Query: 723 EPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQG------------------LTGMPG 764 PG G PG G+PG +G G AG G GPRGE+G L G PG Sbjct: 598 LPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG 657 Query: 765 IRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGI------------KGEPGAPGKIVTSE 812 GP G SG G PG GP G QG+PG G GI KG GAPGK + Sbjct: 658 TDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGK----D 713 Query: 813 GSSMLTVP-GPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS 871 G LT P GPPGP GA G G G PGPAG AG G GPPGP G GPPG Sbjct: 714 GGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGAD 773 Query: 872 IPGPPGPRGPPGE-------GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPG 924 G PG +G GE G PGP GP G+ GP GP G GPKG +G G Sbjct: 774 --GQPGAKGEQGEAGQKGDAGAPGPQGPSGA---------PGPQGPTGVTGPKGARGAQG 822 Query: 925 PRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGI-----PSG 979 P G G G G S+ GPPGP G GPKG +GD G PG G P+G Sbjct: 823 PPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAG 882 Query: 980 P----SEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSY----- 1030 P E G GPPGP G G G + GQ ++ Sbjct: 883 PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPG 942 Query: 1031 LSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAV 1090 SG +GPPGP GPPG +T GE G S + D A Sbjct: 943 ASGDRGPPGPVGPPG-LTGPAGE-----------------PGREGSPGADGPPGRDGAAG 984 Query: 1091 LQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSL--DYAELSSRILSYMSSSGISIGLP 1148 ++ D +G G PGPPG+ G D E ++ S + G+ Sbjct: 985 VKGDRG----ETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQ 1040 Query: 1149 GPPGPPGLPGTSYEELLSLLRGSE-FRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHT 1207 GP GP G G + E L+G F G+ G PGPPGP G Sbjct: 1041 GPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSG-------------------D 1081 Query: 1208 AGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPP 1267 G S GP GP GPPGP GP G GA R S T P GPP Sbjct: 1082 QGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGR--SGETGP------AGPP 1133 Query: 1268 GPPGPQGPPG 1277 G PGP GPPG Sbjct: 1134 GNPGPPGPPG 1143 Score = 194 bits (494), Expect = 4e-49 Identities = 184/612 (30%), Positives = 223/612 (36%), Gaps = 106/612 (17%) Query: 914 PGPKGDQGPPGP-RGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPG 972 PGPKG +G PG + G +G PG QGP G GP+G +GDKG+ G PG Sbjct: 31 PGPKGQKGEPGDIKDIVGPKGPPG------------PQGPAGEQGPRGDRGDKGEKGAPG 78 Query: 973 ALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLS 1032 G P G+ GPPGPPGPPGPPG + ++ E + + Sbjct: 79 PRGRDGEPGTPGNP------GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQL-GVMQ 131 Query: 1033 GVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQ 1092 G GP GP GPPGP + F G +S Sbjct: 132 GPMGPMGPRGPPGPAGAPGPQGFQ---------------GNPGEPGEPGVSGP------- 169 Query: 1093 RDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPG 1152 MGPRGPPGPPG GD + G G PG PG Sbjct: 170 ------------MGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFP-GTPGLPG 216 Query: 1153 P------PGLPGTSYEELLSLLRG-SEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYL 1205 PGL G E ++G S G G PGP GP G+PG + + Sbjct: 217 VKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRT----GPAGAA 272 Query: 1206 HTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVG 1265 G PGP GPPGP GP G PG GA R P+ G Sbjct: 273 GARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARG--------PEGAQGPRG 324 Query: 1266 PPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGG--GGAGSLGA 1323 PG PG GP G S TD G+ S+ + + + G G G LG Sbjct: 325 EPGTPGSPGPAGASGNPGTDGIP--GAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGP 382 Query: 1324 GGAFGEAA-----GDRGPYGTD--IGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNEL 1376 G GE G++GP G GP G G A E G G G G E Sbjct: 383 KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPP--GER 440 Query: 1377 AVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAI 1436 + Q G+A GP G PG +GP G++ A + + Sbjct: 441 GAPGNRGFPGQ---DGLA----GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGL 493 Query: 1437 QGPPGQKGEMGTPGPKGDRGPAGPPGHPGP------------PGPRGHKGEKGDKGDQVY 1484 G PG G G GP G G G PG PGP PGP+G GE G G++ Sbjct: 494 TGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL 553 Query: 1485 AGRRRRRSIAVK 1496 G R + K Sbjct: 554 PGAPGLRGLPGK 565 Score = 109 bits (272), Expect = 2e-23 Identities = 64/153 (41%), Positives = 75/153 (49%), Gaps = 27/153 (17%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 ++G GP+GD G G G+RG G G G G PGP GP G +G+ G GP G RG Sbjct: 1039 IQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGA---SGPAGPSGPRG 1095 Query: 625 REGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGL 684 GP+GP SG+ G G G GP GP G G GP G G+PGP GPPGP G Sbjct: 1096 PPGPVGP--------SGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG- 1146 Query: 685 QGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGP 717 PG+ D GP+ EKGP Sbjct: 1147 ---------PGI--DMSAFAGLGPR----EKGP 1164 Score = 82.4 bits (202), Expect = 3e-15 Identities = 81/278 (29%), Positives = 96/278 (34%), Gaps = 96/278 (34%) Query: 1220 PGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDS 1279 PGP G +G PG D++ IVGP GPPGPQGP G+ Sbjct: 31 PGPKGQKGEPG---------------------------DIKD-IVGPKGPPGPQGPAGEQ 62 Query: 1280 RLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGT 1339 RG RG G G+ G G GE P Sbjct: 63 G--------PRGD----------RGDK---------GEKGAPGPRGRDGEPGTPGNP--- 92 Query: 1340 DIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQG 1399 GP G G G+ GG A AG D ++ G++QG + G Sbjct: 93 --GPPGPPGPPGPPGL----GGNFAAQMAGGFDEKAGGAQL-------GVMQGPMGPM-G 138 Query: 1400 PPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAG 1459 P G PGP G PG QG G GE G PG G GP G Sbjct: 139 PRGPPGPAGAPGP------------------------QGFQGNPGEPGEPGVSGPMGPRG 174 Query: 1460 PPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 PPG PG PG G G+ G G++ G + R P Sbjct: 175 PPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTP 212 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 487 bits (1253), Expect = e-137 Identities = 386/1079 (35%), Positives = 452/1079 (41%), Gaps = 206/1079 (19%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPG---------IPGPLGHPGPQGPKGQKGSVGDPGME 617 G PGP+GD G GP+G +G PG PG +PG G PGP GP G +G +GDPG Sbjct: 1329 GLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPR 1388 Query: 618 GPMGQRGR--EGPMGPRGEAGPPGSGEKGER-------GAAGEPGPHGPPGVPGSVGPKG 668 GP G G +G G RGE GPPG GE G G G PGP GP G PG G KG Sbjct: 1389 GPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKG 1448 Query: 669 SS--GSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGM 726 S G+PG G PG G QG RG PG G KG G PGP G+ GEKG RG G G Sbjct: 1449 DSEDGAPGLPGQPGSPGEQGPRGP---PGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGS 1505 Query: 727 RGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPP--GPSGDPGKPGLTGPQ 784 RGLPG G PGAKG GP GP G QG +GE G G P + GP GP G+ G G GP+ Sbjct: 1506 RGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPR 1565 Query: 785 GPQGLPGT--------PGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPG 836 G G+ G PG PG KG+PG G I + + PG GPPG G PG PG Sbjct: 1566 GATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGP---PGDSGPPGEKGDPGRPG 1622 Query: 837 APGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGP-SIPGPPGPRGPPGE----GLPGPPG 891 PGP GP G G +GPPG PG G G + G PG RGP GE G PG G Sbjct: 1623 PPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDG 1682 Query: 892 PPGSFLSNSETFLSGPPGPPGPPG-------------PKGDQGPPGPRGHQGEQGLPGF- 937 GS S+ G PGPPGPPG GD+G GPRG +G+ GLPG Sbjct: 1683 RNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAP 1742 Query: 938 STSGSSSFGLNLQGPPGPPG------PQGPKGDKGDPGVPGALGI--------PSGPSEG 983 G F +GPPGP G P G KGD+G PG+ G G+ PSGP+ Sbjct: 1743 GERGIEGF----RGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGA 1798 Query: 984 ----------------GSSSTMYVSGPPGPPGPPGP---------------PGSISSSGQ 1012 G SGPPG PG PG PG G+ Sbjct: 1799 AGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGE 1858 Query: 1013 EIQQYISEYMQSDSIRSY-----LSGVQGPPGPPGPPGP-------VTTITGETFDYSEL 1060 + S D + + G QGPPG PGP GP V TG D E Sbjct: 1859 KGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGET 1918 Query: 1061 AS--------------------HVVSYLRTSGYGVSLFSSSI-----SSEDILAVLQRDD 1095 S +V L T+G S + SS L V +R Sbjct: 1919 GSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPER-- 1976 Query: 1096 VRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPG 1155 R+ G G GPPG G + G+++G GPPGP G Sbjct: 1977 -----RRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSG 2031 Query: 1156 L------------------------PGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGN 1191 L PG E RG + R GPPG PG PG PG Sbjct: 2032 LAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRD--GPPGLPGTPGPPGP 2089 Query: 1192 VWSSISVED----LSSYLHTAGLSFIPGPPGP---PGPPGPRGPPGVSGALATYAAENSD 1244 +SV++ LS GL G PG GP G RG PG+ G D Sbjct: 2090 PGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQD 2149 Query: 1245 S---FRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSV 1301 E + P+ + + GP GPPGP G GD A G + S + Sbjct: 2150 GNPGLPGE--RGMAGPEGKPGLQGPRGPPGPVGGHGDPG--PPGAPGLAGPAGPQGPSGL 2205 Query: 1302 RRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGG 1361 + TG G G G GA G G GP G +GP G G + G G G Sbjct: 2206 K-----GEPGETGPPGRGLTGPTGAVG-LPGPPGPSGL-VGPQGSPGLPGQVGE-TGKPG 2257 Query: 1362 LLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSN 1421 G D A D + + V S G + GP G+PGP G PG + V Sbjct: 2258 APGRDGASGKDGDRGSPGVPGSPGLPGPV--------GPKGEPGPTGAPGQAVV--GLPG 2307 Query: 1422 VTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKG 1480 + G + G PG KG+ G PGP+G++G AG G PG PG G KG G KG Sbjct: 2308 AKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKG 2366 Score = 459 bits (1181), Expect = e-129 Identities = 362/1030 (35%), Positives = 424/1030 (41%), Gaps = 261/1030 (25%) Query: 565 LRGSPGPKGD---------MGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPG 615 L G PGPKGD G GP GD G PG G PG G PGP GP+G+ G VG+ G Sbjct: 1581 LPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKG 1640 Query: 616 MEGPMGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPG 674 EGP G G G G RG G PG G GE+G G+PG G G PGS GPKG G PG Sbjct: 1641 DEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPG 1700 Query: 675 PQGPPGPV-------------------GLQGLRGEVGLPGVKGDKGP---MGPPGPKGDQ 712 P GPPG + G +G +G+ GLPG G++G GPPGP+GD Sbjct: 1701 PPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDP 1760 Query: 713 GEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGP---P 769 G +GP G G+ G GL G G G GA GP+GP+G G G+ G G+PG+RG P Sbjct: 1761 GVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLP 1820 Query: 770 GPSGDP---------GKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEG------- 813 GPSG P GKPGL G G G PG GR G KG+ GA G+ EG Sbjct: 1821 GPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGR----EGRDGPKGE 1876 Query: 814 ---SSMLTVPGPPGPPGAMGPPGP--PGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPP 868 +L GPPG PG +GPPG PG PG GP G G QG PG G RG P Sbjct: 1877 RGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEP 1936 Query: 869 G--PSI-----------------------------PGPPGPRGPPGE-GLPGPPGPPGSF 896 G P++ P P RGP G+ G GPPG G Sbjct: 1937 GSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPI 1996 Query: 897 LSNSETFLSGPPGPPGPPGPK----GDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGP 952 E L G G PGP GP G++GPPGP G GE G PG + G+ G Sbjct: 1997 GFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGR 2056 Query: 953 PGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQ 1012 PG G +G KG++G+ G G G+P G PGPPGPPGP S+ G Sbjct: 2057 PGERGERGEKGERGEQGRDGPPGLP---------------GTPGPPGPPGPKVSVDEPGP 2101 Query: 1013 EIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLR--- 1069 LSG QGPPG G G G D V ++ Sbjct: 2102 G-----------------LSGEQGPPGLKGAKGE----PGSNGDQGPKGDRGVPGIKGDR 2140 Query: 1070 -TSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYA 1128 G + + E +A + + L GPRGPPGP G GD Sbjct: 2141 GEPGPRGQDGNPGLPGERGMAGPEG-------KPGLQGPRGPPGPVGGHGD--------- 2184 Query: 1129 ELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPP-----GPP 1183 PGPPG PGL G + + S L+G G GPP GP Sbjct: 2185 -------------------PGPPGAPGLAGPAGPQGPSGLKGEP--GETGPPGRGLTGPT 2223 Query: 1184 GPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENS 1243 G G+PG G S + GP G PG PG G G GA A Sbjct: 2224 GAVGLPG----------------PPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGK 2267 Query: 1244 DSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRR 1303 D R SP V G PG PGP GP G+ G + + + V Sbjct: 2268 DGDRG-------SPGV----PGSPGLPGPVGPKGEP-----------GPTGAPGQAVVGL 2305 Query: 1304 GSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLL 1363 + + GG +G GA G+ G GP G + G G G + G G Sbjct: 2306 PGAKGEKGAPGGLAGDLVGEPGAKGD-RGLPGPRG-EKGEAGRAGEPGDPGEDGQKGAPG 2363 Query: 1364 GADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVT 1423 F GD G PG PGP GPPG+ Sbjct: 2364 PKGFKGDPGV-------------------------GVPGSPGPPGPPGVKGDLGLPGLPG 2398 Query: 1424 ADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGH---------PGPP---GPRG 1471 A + F G G +GEMG PGP G+RG AGPPG PGPP GP G Sbjct: 2399 APGVVGF------PGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPG 2452 Query: 1472 HKGEKGDKGD 1481 G KGDKGD Sbjct: 2453 ASGLKGDKGD 2462 Score = 450 bits (1158), Expect = e-126 Identities = 358/1035 (34%), Positives = 425/1035 (41%), Gaps = 223/1035 (21%) Query: 560 QENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGH---------------PGPQGP 604 Q + +RG G KGD G PG G G G PG GP G PG +G Sbjct: 1757 QGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGE 1816 Query: 605 KGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPG-------------------SGEKGE 645 +G G G PG+ G G+ G+ G G GE G PG G KGE Sbjct: 1817 QGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGE 1876 Query: 646 RGAAGEPGPHGPPGVPGSVGPKGSS--GSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPM 703 RGA G GP GPPG+PG VGP G G PG GP G G G +GE GLPG +G +G Sbjct: 1877 RGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEP 1936 Query: 704 GP---------------------------------------PGPKGDQGEKGPRGLTGE- 723 G GPKGD GE+GP G G Sbjct: 1937 GSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPI 1996 Query: 724 --PGMRGLPGAVGEPGAKG----AMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGK 777 PG RGL G G+PG +G A+G GP G G GE G G+PG+ G G G+ G+ Sbjct: 1997 GFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGR 2056 Query: 778 P------GLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSE--GSSMLTVPGPPGPPGAM 829 P G G +G QG G PG PG G PG PG V+ + G + GPPG GA Sbjct: 2057 PGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAK 2116 Query: 830 GPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG-PSIPGPPGPRGPPGE-GLP 887 G PG G GP G G+PG ++G G PGPRG G P +PG G GP G+ GL Sbjct: 2117 GEPGSNGDQGPKGDRGVPG------IKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQ 2170 Query: 888 GPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGL 947 GP GPPG + + GPPG PG GP G QGP G +G GE G PG +G + + Sbjct: 2171 GPRGPPGPVGGHGD---PGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTG-AV 2226 Query: 948 NLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSI 1007 L GPPGP G GP+G G PG G G P P G+S G PG PG PG PG + Sbjct: 2227 GLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPV 2286 Query: 1008 SSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTT----ITGETFDYSELASH 1063 G +G PGP G PG GE LA Sbjct: 2287 -------------------------GPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGD 2321 Query: 1064 VVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLL 1123 +V G + L GPRG G G +G+ Sbjct: 2322 LVGEPGAKG----------------------------DRGLPGPRGEKGEAGRAGEPGDP 2353 Query: 1124 SLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPP 1183 D + + + G +G+PG PGPPG PG + L L G+ G+VG PG Sbjct: 2354 GEDGQKGAPGPKGFKGDPG--VGVPGSPGPPGPPGVKGDLGLPGLPGAP--GVVGFPGQT 2409 Query: 1184 GPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYA--AE 1241 GP G G S G IPGP GPPGPPG GPPG SG Sbjct: 2410 GPRGEMGQPGPS----GERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGV 2465 Query: 1242 NSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSV 1301 R E P +R G G PG +GP G L S S+ Sbjct: 2466 GLPGPRGE----RGEPGIR----GEDGRPGQEGPRG---LTGPPGSRGERGEKGDVGSAG 2514 Query: 1302 RRGSSYSSSMSTGGGGAGSLGAGGAFGEAA-----GDRGPYGTDIGPGGGYGAAAEGGMY 1356 +G S++ G G GA G GE GD+GP G D G G G+ E G Sbjct: 2515 LKGDKGDSAVIL--GPPGPRGAKGDMGERGPRGLDGDKGPRG-DNGDPGDKGSKGEPG-D 2570 Query: 1357 AGNGGLLGADFAGDLDYNELAVRVSESMQRQGLL----QGMAYTVQGPPGQPGPQGPPGI 1412 G+ GL G +GLL Q A + G PG PG G PGI Sbjct: 2571 KGSAGLPGL---------------------RGLLGPQGQPGAAGIPGDPGSPGKDGVPGI 2609 Query: 1413 SKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGH 1472 D+ F ++G G KG G G KGD+G AGPPG PG G +G Sbjct: 2610 -------RGEKGDV--GFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGE 2660 Query: 1473 KGEKGDKGDQVYAGR 1487 GE G G G+ Sbjct: 2661 MGEPGVPGQSGAPGK 2675 Score = 439 bits (1129), Expect = e-122 Identities = 353/1009 (34%), Positives = 425/1009 (42%), Gaps = 190/1009 (18%) Query: 522 DRLQGMAPAAGADLDKIGLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGP- 580 DRL A + L +I D ++ V ++ + + +G PG +G +G PG Sbjct: 1943 DRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGER 2002 Query: 581 --KGDRGFPGTPGIPG-PLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGP 637 KGDRG PG G PG LG GP GP G G G PG+ G G+ G G G GE G Sbjct: 2003 GLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGE 2062 Query: 638 PG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGP--QGPPGPVGLQGLRGEVGLP 694 G GE+GE+G G PG G PG PG GPK S PGP G GP GL+G +GE G Sbjct: 2063 RGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSN 2122 Query: 695 GVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGM------------------RGLPGAV--- 733 G +G KG G PG KGD+GE GPRG G PG+ RG PG V Sbjct: 2123 GDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGH 2182 Query: 734 ---GEPGAKGAMGPAGPDGHQGPRGEQGLTGMP--GIRGPPGPSGDPGKPGLTGPQGPQG 788 G PGA G GPAGP G G +GE G TG P G+ GP G G PG PG +G GPQG Sbjct: 2183 GDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQG 2242 Query: 789 LPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPG 848 PG PG+ G G+PGAPG+ S PG PG PG GP GP G PGP G G Sbjct: 2243 SPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPG--- 2299 Query: 849 HQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPP 908 Q V+ L G G G G + G PG +G GLPGP G G +G Sbjct: 2300 -QAVVGLPGAKGEKGAPGGLAGDLVGEPGAKG--DRGLPGPRGEKGE---------AGRA 2347 Query: 909 GPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDP 968 G PG PG G +G PGP+G +G+ G + + G PGPPGP G KGD G P Sbjct: 2348 GEPGDPGEDGQKGAPGPKGFKGDPG-------------VGVPGSPGPPGPPGVKGDLGLP 2394 Query: 969 GVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIR 1028 G+PGA G+ P + G M GP G G GPPG R Sbjct: 2395 GLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPG----------------------R 2432 Query: 1029 SYLSGVQGPPGPPGPPGP--VTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSED 1086 + G GPPGPPG GP + + G+ D + G I ED Sbjct: 2433 EGIPGPLGPPGPPGSVGPPGASGLKGDKGDPG---------VGLPGPRGERGEPGIRGED 2483 Query: 1087 ILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIG 1146 R GPRG GPPG+ G+ + ++ S L G S Sbjct: 2484 -------------GRPGQEGPRGLTGPPGSRGERG----EKGDVGSAGLK--GDKGDSAV 2524 Query: 1147 LPGPPGPPGLPGTSYEELLSLLRGSEF-RGIVGPPGPPGPPGIPGNVWSSISVEDLSSYL 1205 + GPPGP G G E L G + RG G PG G G PG+ S + L L Sbjct: 2525 ILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDK-GSAGLPGLRGLL 2583 Query: 1206 HTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVG 1265 G G PG PG PG G PG+ G E D VG Sbjct: 2584 GPQGQPGAAGIPGDPGSPGKDGVPGIRG-------EKGD-------------------VG 2617 Query: 1266 PPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGG--GGAGSLGA 1323 GP G +G G D +G + + + M G G +G+ G Sbjct: 2618 FMGPRGLKGERGVKGACGLDG--EKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGK 2675 Query: 1324 GGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSES 1383 G G GDRG + GP G G E G G GG G +G+ Sbjct: 2676 EGLIG-PKGDRG-FDGQPGPKGDQGEKGERGT-PGIGGFPGP--SGN------------- 2717 Query: 1384 MQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQK 1443 G A GPPG GP+GP G+ Q +GPPG++ Sbjct: 2718 -------DGSA-GPPGPPGSVGPRGPEGL------------------QGQKGERGPPGER 2751 Query: 1444 GEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRS 1492 +G PG G G G G PGP GPRG KGE D + R+ S Sbjct: 2752 -VVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQEMS 2799 Score = 392 bits (1007), Expect = e-108 Identities = 347/1018 (34%), Positives = 400/1018 (39%), Gaps = 241/1018 (23%) Query: 619 PMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGP 678 P GQ+G G MG RG+ GPPG + G G G PGP GPPG S KG G PG G Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPG--DPGLPGRTGAPGPQGPPG---SATAKGERGFPGADGR 1306 Query: 679 PGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAV----- 733 PG G G G G PG+KG G PGP+GD GE+GPRG GEPG PG V Sbjct: 1307 PGSPGRAGNPGTPGAPGLKGSPGL---PGPRGDPGERGPRGPKGEPGA---PGQVIGGEG 1360 Query: 734 -GEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLT----------- 781 G PG KG GP+GP G +GP G+ PGP G PG PG Sbjct: 1361 PGLPGRKGDPGPSGPPGPRGPLGD------------PGPRGPPGLPGTAMKGDKGDRGER 1408 Query: 782 GPQGP---------QGLPGTPGRPGIKGEPGAPGKIVTSEGS--SMLTVPGPPGPPGAMG 830 GP GP GLPG PG PG +G G PGK S +PG PG PG G Sbjct: 1409 GPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQG 1468 Query: 831 PPGPPGA------------------------PGPAGPAGLPGHQEVLNLQGPPGPPGP-- 864 P GPPGA PGPAG GLPG +GP GPPGP Sbjct: 1469 PRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTG 1528 Query: 865 ----RGPP---------GPSIPGP------------------PGPRGPPGEGLPGPPGP- 892 +G P GP++ GP G RGPPG LPG PGP Sbjct: 1529 RQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPK 1588 Query: 893 --PGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPR------------GHQGEQGLPGFS 938 PG T +GPPG GPPG KGD G PGP G +G++G PG Sbjct: 1589 GDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDP 1648 Query: 939 TSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPP 998 + L+G PG GP G KGD+GDPG G G P GSS G PGPP Sbjct: 1649 GLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSP------GSSGPKGDRGEPGPP 1702 Query: 999 GPP-------------GPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPG 1045 GPP G PG G + + R + G +GPPGP G PG Sbjct: 1703 GPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERG-IEGFRGPPGPQGDPG 1761 Query: 1046 PVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYL----- 1100 V GE D SG ++ S + A D R L Sbjct: 1762 -VRGPAGEKGDRGPPGLD-----GRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRG 1815 Query: 1101 RQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTS 1160 Q L GP GPPG PG G+ L+ G G PG PG G Sbjct: 1816 EQGLPGPSGPPGLPGKPGEDGKPGLN-------------------GKNGEPGDPGEDGRK 1856 Query: 1161 YEELLSLLRGSEFR----------GIVGPPGPPGPPGIPGNVWSSI-SVEDLSSYLHTAG 1209 E+ S G E R GI+GP GPPG PG G V + G Sbjct: 1857 GEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRG 1916 Query: 1210 LSFIPGPPGPPGPPGPRGPPG----------VSGALATYAAENSDSFRSELISYLTSPDV 1259 + G G PG G RG PG +G A+ E +++ S+L P+ Sbjct: 1917 ETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPER 1976 Query: 1260 RSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAG 1319 R GP G G QGPPG + RG G G Sbjct: 1977 RR---GPKGDSGEQGPPGKEGPIGFPG--ERGLK----------------------GDRG 2009 Query: 1320 SLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVR 1379 G G G A G+RGP GP G G + G+ G G AG R Sbjct: 2010 DPGPQGPPGLALGERGP----PGPSGLAGEPGKPGIPGLPGRAGGVGEAG---------R 2056 Query: 1380 VSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGP 1439 E +R + GPPG PG GPPG V+ D + QGP Sbjct: 2057 PGERGERGEKGERGEQGRDGPPGLPGTPGPPG-----PPGPKVSVD--EPGPGLSGEQGP 2109 Query: 1440 PGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 PG KG G PG GD+GP G G PG G RG G +G G+ G R KP Sbjct: 2110 PGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKP 2167 Score = 194 bits (492), Expect = 7e-49 Identities = 211/706 (29%), Positives = 254/706 (35%), Gaps = 159/706 (22%) Query: 864 PRGPPGPSIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGP 922 PR P P + P G +G PGE GL G GPPG PG PG G G QGP Sbjct: 1242 PRPEPCP-VYCPKGQKGEPGEMGLRGQVGPPGD------------PGLPGRTGAPGPQGP 1288 Query: 923 PGPRGHQGEQGLPGF-------------STSGSSSF--GLNLQGPPGPPGPQGPKGDKGD 967 PG +GE+G PG T G+ L GP G PG +GP+G KG+ Sbjct: 1289 PGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGE 1348 Query: 968 PGVPGALGIPSGPSEGGSSSTMYVSGPPGP------PGPPGPPG----SISSSGQEIQQY 1017 PG PG + GP G SGPPGP PGP GPPG ++ + + Sbjct: 1349 PGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGER 1408 Query: 1018 ISEYMQSDSIRSYLSGVQGPPGPPGPPGPV--TTITGETFDYSELASHVVSYLRTSGYGV 1075 I G+ G PG PGP GPV GE D + A + + G Sbjct: 1409 GPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGE-- 1466 Query: 1076 SLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGD----GSLLSLDY---- 1127 GPRGPPG G GD G L Sbjct: 1467 -----------------------------QGPRGPPGAIGPKGDRGFPGPLGEAGEKGER 1497 Query: 1128 ---AELSSRILSYMSSSGISIGLPGPPGP---------PGLPGTSYEELLSLLRGSEFRG 1175 SR L ++ + G GPPGP PG PG ++ +G Sbjct: 1498 GPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKG 1557 Query: 1176 IVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGAL 1235 VGP GP G G+ G GL +PG PGP G PG RGP G++G Sbjct: 1558 DVGPAGPRGATGVQGE-------------RGPPGL-VLPGDPGPKGDPGDRGPIGLTGR- 1602 Query: 1236 ATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGP---------------QGPPGDSR 1280 A DS P G PGPPGP +GPPGD Sbjct: 1603 ---AGPPGDS----------GPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPG 1649 Query: 1281 LLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYG-- 1338 L + +G G GS G G GE G GP G Sbjct: 1650 LPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGE-PGPPGPPGRL 1708 Query: 1339 TDIGPG----GGYGAAAEGGMYA--GNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQG 1392 D GPG G G + G G+ GL GA ++ R Q ++G Sbjct: 1709 VDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIE----GFRGPPGPQGDPGVRG 1764 Query: 1393 MAYTV--QGPP---------GQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPG 1441 A +GPP G+PG GP G + + D + + + GP G Sbjct: 1765 PAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSG 1824 Query: 1442 QKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGR 1487 G G PG G G G G PG PG G KGEKGD G GR Sbjct: 1825 PPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGR 1870 Score = 156 bits (395), Expect = 1e-37 Identities = 174/594 (29%), Positives = 213/594 (35%), Gaps = 170/594 (28%) Query: 931 EQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMY 990 +Q + G +T+ + Q P P PKG KG+PG G G P + G Sbjct: 1223 DQAVSGLATALCQA-SFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPG------ 1275 Query: 991 VSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTT- 1049 + G G PGP GPPGS ++ G+ + +D R G G PG PG PG + Sbjct: 1276 LPGRTGAPGPQGPPGSATAKGER------GFPGADG-RPGSPGRAGNPGTPGAPGLKGSP 1328 Query: 1050 -ITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPR 1108 + G D E R I E ++ D GP Sbjct: 1329 GLPGPRGDPGERGP------RGPKGEPGAPGQVIGGEGPGLPGRKGD---------PGPS 1373 Query: 1109 GPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLL 1168 GPPGP G GD PGP GPPGLPGT+ + Sbjct: 1374 GPPGPRGPLGD----------------------------PGPRGPPGLPGTA-------M 1398 Query: 1169 RGSEFRGIVGPPGPPGP------PGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGP 1222 +G +G G GPPGP PG PG +PG PG PGP Sbjct: 1399 KGD--KGDRGERGPPGPGEGGIAPGEPG----------------------LPGLPGSPGP 1434 Query: 1223 PGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLL 1282 GP GPPG G E D S D + G PG PG QGP G + Sbjct: 1435 QGPVGPPGKKG-------EKGD-----------SEDGAPGLPGQPGSPGEQGPRGPPGAI 1476 Query: 1283 STDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIG 1342 RG G AGS G G G G +GP G G Sbjct: 1477 GPKGDRGFPGPLGEAGEKGERGPP---------GPAGSRGLPGVAGR-PGAKGPEGPP-G 1525 Query: 1343 PGGGYGAAAEGGMYAGNGGLLGADFAGDL----DYNELAVRVSESMQRQGLLQGMAYTVQ 1398 P G G E G G+ ++G AG D R + +Q + G+ Sbjct: 1526 PTGRQGEKGEPGR-PGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGD 1584 Query: 1399 -GPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGP------ 1451 GP G PG +GP G+ + + D GPPG+KG+ G PGP Sbjct: 1585 PGPKGDPGDRGPIGL----TGRAGPPGD-----------SGPPGEKGDPGRPGPPGPVGP 1629 Query: 1452 ---------KGDRGPAGPPGHP---------GPPGPRGHKGEKGDKGDQVYAGR 1487 KGD GP G PG P G PG RG GEKGD+GD GR Sbjct: 1630 RGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGR 1683 >gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] Length = 1860 Score = 473 bits (1217), Expect = e-133 Identities = 351/982 (35%), Positives = 424/982 (43%), Gaps = 149/982 (15%) Query: 566 RGSPGPKG---DMGSPGPKGD---RGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGP 619 +G PGP G + G PGP+G +G+PG G+PGP+G PGP+G +G G G G+ G Sbjct: 711 KGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGS 770 Query: 620 MGQRGREGPMGPRGEAGPPGS----GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGP 675 G+RG G G RG+ G PG GE+G G G PG G PG PG G G G GP Sbjct: 771 DGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGP 830 Query: 676 QGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGD---QGEKGPRGLTGEPGMRGLPGA 732 G PGP G++GL G VG PG+KGDKG G PG GD QG+KG +GL G PG RG PG Sbjct: 831 IGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGP 890 Query: 733 VGEPGAKGAMG---PAGPDGHQGP------RGEQGLTGMPGIRGPPGPSGDPGKPGLTGP 783 +G+ G KG++G P GP+G G G +G+ G PG RG PGP G G G GP Sbjct: 891 LGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGP 950 Query: 784 QGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGP 843 GP G PG G+PG KG PG PG + PG PG PG +G G G G G Sbjct: 951 MGPPGAPGLEGQPGRKGFPGRPGL------DGVKGEPGDPGRPGPVGEQGFMGFIGLVGE 1004 Query: 844 AGLPGHQEVLNLQGPPGPPGPRG-------PPGPSIPGPPGPRGPPG----------EGL 886 G+ G + + GPPG PGP+G P G PG PGP+GPPG +G Sbjct: 1005 PGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGR 1064 Query: 887 PGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFG 946 GP GP G L GPPGP G PG G QG G RGH G +G PG Sbjct: 1065 RGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGT 1124 Query: 947 LNLQGPPGPPGPQGP---KGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGP 1003 L G PGP GPQGP G+ G G PGA+G P P E G + G GP G PG Sbjct: 1125 KGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAG------MKGDLGPLGTPGE 1178 Query: 1004 PGSISSSGQEIQQYISEYMQSDSIRSYLS--------------GVQGPPGPPGPPGPVTT 1049 G I G+ + S M D ++ G+ G GPPGPPG VT Sbjct: 1179 QGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPG-VTG 1237 Query: 1050 ITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRG 1109 + G + RT G + + MG G Sbjct: 1238 VRGPEGKSGKQGEKG----RTGAKGAKGYQGQLGE--------------------MGVPG 1273 Query: 1110 PPGPPGASGD-GSLLSLDYAELSSRILSYMSSSGIS-----IGLPGPPGPPGLPGTSYEE 1163 PGPPG G GS SL R + G++ G+ GP GPPG G E+ Sbjct: 1274 DPGPPGTPGPKGSRGSLGPTGAPGR-MGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQ 1332 Query: 1164 LLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVED--LSSYLHTAGLSFIPGPPGPPG 1221 E GPPGPPG G G+ D GL PG G PG Sbjct: 1333 -------GEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPG 1385 Query: 1222 PPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSF--IVGPPGPPGPQGPPGDS 1279 PGPRG PG G+ + +P R + G PGP G G G Sbjct: 1386 HPGPRGWPGPKGSKGAEGPKGKQGKAG-------APGRRGVQGLQGLPGPRGVVGRQGLE 1438 Query: 1280 RLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAA--GDRGPY 1337 + D R + G + G G G GA G G+ G Sbjct: 1439 GIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLP 1498 Query: 1338 GTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMA--Y 1395 G +GP G G G+ GN G G+ D E+ GMA + Sbjct: 1499 G-QLGPPGKRGTEGRTGL-PGNQGEPGSKGQPG-DSGEMG------------FPGMAGLF 1543 Query: 1396 TVQGPPGQ------PGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTP 1449 +GPPG GP+GPPG+ + L + + GP G KG G Sbjct: 1544 GPKGPPGDIGFKGIQGPRGPPGLM----GKEGIVGPLGILGPS--GLPGPKGDKGSRGDW 1597 Query: 1450 GPKGDRGPAGPPGHPGPPGPRG 1471 G +G RGP GP G PGPPGP G Sbjct: 1598 GLQGPRGPPGPRGRPGPPGPPG 1619 Score = 469 bits (1206), Expect = e-131 Identities = 364/1012 (35%), Positives = 437/1012 (43%), Gaps = 186/1012 (18%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGI------PGPLGHPGPQGPKGQKGSVGDPGMEG 618 L G PGPKGD G PGP G G PG PG PGP G+PG GP G KG GDPG+ Sbjct: 623 LMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSP 682 Query: 619 PMGQRGREGPMGPRGEAGPPG----SGEKGERGAAGEPGPHGPPGVPGSVGPKG---SSG 671 G +G MG G +G PG G KG G AG PG G PG GS G KG G Sbjct: 683 GKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQG 742 Query: 672 SPGPQGPPGP------------VGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRG 719 PGP G PGP GL G GE GLPGV G +G MG PG G GE+GP G Sbjct: 743 LPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPG 802 Query: 720 LTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGM---PGIRGPPGPSGDPG 776 L G PG GLPG G PG G +G GP G+ GP+G +GL G PG++G G G PG Sbjct: 803 LDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPG 862 Query: 777 KPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPG 836 G G QG +G G PG PG +G+PG GK V +GS + PGPPGP G G GPPG Sbjct: 863 VSGDPGFQGDKGSQGLPGFPGARGKPGPLGK-VGDKGS--IGFPGPPGPEGFPGDIGPPG 919 Query: 837 APGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPG-EGLPGPPGPPGS 895 GP G G PG + + +G GP G GP GP PG PG G PG +G PG PG G Sbjct: 920 DNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGP--PGAPGLEGQPGRKGFPGRPGLDG- 976 Query: 896 FLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGP 955 + G PG PG PGP G+QG G G GE G+ G +G GP Sbjct: 977 --------VKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGD---------RGMMGP 1019 Query: 956 PGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQ 1015 PG GPKG G PG+PG +G P P GP GPPG GPPG + G+ Sbjct: 1020 PGVPGPKGSMGHPGMPGGMGTPGEP------------GPQGPPGSRGPPGMRGAKGRRGP 1067 Query: 1016 QYISEYMQSDSIRSYLSGVQGPPGPPGPPG--PVTTITGETFDYSELASHVVSYLRTSGY 1073 + R G++GPPGP G PG + GE +L + G+ Sbjct: 1068 RGPDGPAGEQGSR----GLKGPPGPQGRPGRPGQQGVAGER-----------GHLGSRGF 1112 Query: 1074 -GVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPP------GPPGASGDGSL---- 1122 G+ S ++ + + Q GP GPP GPPGA G+ L Sbjct: 1113 PGIPGPSGPPGTKGLPG--------EPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEA 1164 Query: 1123 -LSLDYAELSS----RILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFR-GI 1176 + D L + ++ G+ G GP GP GL G + G + + G+ Sbjct: 1165 GMKGDLGPLGTPGEQGLIGQRGEPGLE-GDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGL 1223 Query: 1177 VGPPGPPGPPGIPG-----------NVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGP 1225 +G GPPGPPG+ G + Y G +PG PGPPG PGP Sbjct: 1224 MGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGP 1283 Query: 1226 ---RGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQ--------- 1273 RG G +GA A+ L D IVGP GPPGP+ Sbjct: 1284 KGSRGSLGPTGAPGRMGAQGEPG--------LAGYDGHKGIVGPLGPPGPKGEKGEQGED 1335 Query: 1274 -------GPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGA 1326 GPPGD + +G G G G G Sbjct: 1336 GKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGP 1395 Query: 1327 FGEAAGDRGPYGTDIGPGGGYGAAAEGGMYA--GNGGLLGAD-FAGDLDYNELAVRVSES 1383 G + G GP G G G G G+ G G++G G + L R ++ Sbjct: 1396 KG-SKGAEGPKGKQ-GKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQA 1453 Query: 1384 MQRQGLLQGMAYTVQGPPGQPGPQGP------PGISKVFSAYSNVTADLMDFFQTYGAIQ 1437 Q QG QG G PGP GP PG++ + A Q Sbjct: 1454 GQ-QG--------EQGDDGDPGPMGPAGKRGNPGVAGLPGA------------------Q 1486 Query: 1438 GPPGQKGEMGTP---GPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 GPPG KGE G P GP G RG G G PG G G KG+ GD G+ + G Sbjct: 1487 GPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPG 1538 Score = 409 bits (1051), Expect = e-113 Identities = 307/861 (35%), Positives = 377/861 (43%), Gaps = 157/861 (18%) Query: 567 GSPGPKGDMGS---------PGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGME 617 G PG KGD G PG +GD+G G PG PG G PGP G G KGS+G PG Sbjct: 847 GEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPP 906 Query: 618 GPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQG 677 GP G G +GP G+ GP G KG+ GA G PGP G G G GP G G+PG +G Sbjct: 907 GP---EGFPGDIGPPGDNGPEGM--KGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEG 961 Query: 678 PPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQG---------------EKGPRGLTG 722 PG +G G GL GVKG+ G G PGP G+QG EKG RG+ G Sbjct: 962 QPGR---KGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMG 1018 Query: 723 EPGMRGLPGAVGEPGAKGAMG------PAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPG 776 PG+ G G++G PG G MG P GP G +GP G +G G G RGP GP+G+ G Sbjct: 1019 PPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQG 1078 Query: 777 KPGLTGPQGPQGLPGTPGRPGIKGE---------PGAPGKIVTSEGSSMLTVPGPPGPPG 827 GL GP GPQG PG PG+ G+ GE PG PG + PGP GP G Sbjct: 1079 SRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQG 1138 Query: 828 AMGPPG---PPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG----PSIPGPPGPRG 880 +GPPG P G PG G GLPG + GP G PG +G G P + G GP G Sbjct: 1139 PIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMG 1198 Query: 881 PPG-EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFST 939 P G +G G PGP G + L G GPPGPPG G +GP G G QGE+G G Sbjct: 1199 PDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTG--A 1256 Query: 940 SGSSSFGLNL--------QGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYV 991 G+ + L GPPG PGP+G +G G G PG +G P G + Sbjct: 1257 KGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGI 1316 Query: 992 SGPPGPPGP----------------PGPPGS---ISSSGQEIQQYISEYMQSDSIRSYLS 1032 GP GPPGP PGPPG + G + Y + ++ Sbjct: 1317 VGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRG 1376 Query: 1033 --GVQGPPGPPGP---PGPVTTITGETFDYSELASHVVSYLRTSGY-GVSLFSSSISSED 1086 G QG PG PGP PGP + E + + G G+ + + Sbjct: 1377 KPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQG 1436 Query: 1087 ILAVLQRDDVR----QYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSG 1142 + + D + Q +Q G G PGP G +G + G Sbjct: 1437 LEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGK------------------RGNPG 1478 Query: 1143 ISIGLPGPPGPPGLPGTSYEELLSLL-----RGSEFR-GIVGPPGPPGPPGIPGNVWSSI 1196 ++ GLPG GPPG G S L L RG+E R G+ G G PG G PG+ Sbjct: 1479 VA-GLPGAQGPPGFKGES--GLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGD----- 1530 Query: 1197 SVEDLSSYLHTAGLSFIPGPPGPPGP------PGPRGPPG------VSGALATYAAENSD 1244 S + G++ + GP GPPG GPRGPPG + G L Sbjct: 1531 -----SGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLP 1585 Query: 1245 SFRSELISY----LTSPDVRSFIVGPPGP---PGPQGPPGDSRLLSTDASHSRGSSSSSH 1297 + + S L P GPPGP PGP GPPG L D + + Sbjct: 1586 GPKGDKGSRGDWGLQGPR------GPPGPRGRPGPPGPPGGPIQLQQDDLGAAFQTWMDT 1639 Query: 1298 SSSVRRGS-SYSSSMSTGGGG 1317 S ++R S SY + GG Sbjct: 1640 SGALRPESYSYPDRLVLDQGG 1660 Score = 367 bits (941), Expect = e-101 Identities = 313/919 (34%), Positives = 367/919 (39%), Gaps = 203/919 (22%) Query: 658 PGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGP 717 P + G GPKG G PGP G PG G+ G RG G PG G+ G GPPG +G+KG Sbjct: 621 PLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGA---KGQKGD 677 Query: 718 RGLT------------GEPGMRGLPGAVGEPGAKGAMGPAGPDGHQ---GPRGEQGLTGM 762 GL+ G PG+ G PG G G KG GPAG G Q GP G G G Sbjct: 678 PGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGY 737 Query: 763 PGIRGPPGPSGDPGKP------------GLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVT 810 PG +G PGP GDPG GL G G +GLPG PG+ G G PG PG + Sbjct: 738 PGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPG-VFG 796 Query: 811 SEGSSMLTVPGPPGPPGAMGPPGPPGAP------GPAGPAGLPGHQEVLNLQGPPGPPGP 864 G PG G PG +G PGPPG P G GP G PG + + L G G PG Sbjct: 797 ERGP-----PGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGL 851 Query: 865 RGPPG----PSIPGPPGPRGPPG-EGLPGPP---GPPGSFLSNSETFLSGPPGPPGPPGP 916 +G G P + G PG +G G +GLPG P G PG + G PGPPGP G Sbjct: 852 KGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGF 911 Query: 917 KGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGI 976 GD GPPG G +G +G PG +G PGP G GP+GD+G G PGA G+ Sbjct: 912 PGDIGPPGDNGPEGMKGKPG------------ARGLPGPRGQLGPEGDEGPMGPPGAPGL 959 Query: 977 PSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSI-RSYLSGVQ 1035 P G + G G PG PG PG + G +I + + G+ Sbjct: 960 EGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQG--FMGFIGLVGEPGIVGEKGDRGMM 1017 Query: 1036 GPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGY-GVSLFSSSISSEDILAVLQRD 1094 GPPG PGP G S + + T G G S + R Sbjct: 1018 GPPGVPGPKG------------SMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRR 1065 Query: 1095 DVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPP 1154 R GP GP G G+ G L GPPGP Sbjct: 1066 GPR--------GPDGPAGEQGSRG----------------------------LKGPPGPQ 1089 Query: 1155 GLPGTSYEELLSLLRGS-EFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFI 1213 G PG ++ ++ RG RG G PGP GPPG G + Sbjct: 1090 GRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKG----------------------L 1127 Query: 1214 PGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSEL-----ISYLTSPDVRSFI----- 1263 PG PGP GP GP GPPG G A E + L +P + I Sbjct: 1128 PGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGE 1187 Query: 1264 ---VGPPGPPGPQGPPGDSRLLSTDASHSR----------GSSSSSHSSSVRRGSSYSSS 1310 G GP GP G GD D H G + VR S Sbjct: 1188 PGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGK 1247 Query: 1311 MSTGG--GGAGSLGAGGAFGE--AAGDRGPYGTDIGPGGGYGA----AAEGGMYA-GNGG 1361 G G G+ G G GE GD GP GT GP G G+ A G M A G G Sbjct: 1248 QGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTP-GPKGSRGSLGPTGAPGRMGAQGEPG 1306 Query: 1362 LLGAD----FAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFS 1417 L G D G L E QG +GPPG PG +GP G Sbjct: 1307 LAGYDGHKGIVGPLGPPGPKGEKGE--------QGEDGKAEGPPGPPGDRGPVG------ 1352 Query: 1418 AYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGP---PGPRGHKG 1474 D D + G PG G+ G G +G G G PGHPGP PGP+G KG Sbjct: 1353 -------DRGDRGE-----PGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKG 1400 Query: 1475 EKGDKGDQVYAGRRRRRSI 1493 +G KG Q AG RR + Sbjct: 1401 AEGPKGKQGKAGAPGRRGV 1419 Score = 348 bits (894), Expect = 2e-95 Identities = 224/550 (40%), Positives = 268/550 (48%), Gaps = 75/550 (13%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 L G G KGD+G G G++G G G PG G GP GP G KG GDPG +G G++G Sbjct: 1160 LPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKG 1219 Query: 625 REGPMGPRGEAGPPG----------------------SGEKGERGAAGEPGPHGPPGVPG 662 +EG MG G GPPG G KG +G GE G G PG PG Sbjct: 1220 QEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPG 1279 Query: 663 SVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKG----PR 718 + GPKGS GS GP G PG +G QG G G G KG GP+GPPGPKG++GE+G Sbjct: 1280 TPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAE 1339 Query: 719 GLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKP 778 G G PG RG G G+ G G G G +G QG RG+ G G PG GP G G G Sbjct: 1340 GPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSK 1399 Query: 779 GLTGPQGPQGLPGTPGRPGIKGEPGAPGK--IVTSEGSSMLT----VPGPPGPPGAMGPP 832 G GP+G QG G PGR G++G G PG +V +G + +PG G G G Sbjct: 1400 GAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQ 1459 Query: 833 GPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG-PSIPGPPGPRGPPGE-GLPGPP 890 G G PGP GPAG G+ V L G GPPG +G G P GPPG RG G GLPG Sbjct: 1460 GDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQ 1519 Query: 891 GPPGSFLSNSET---------FLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSG 941 G PGS ++ L GP GPPG G KG QGP GP G G++G+ G Sbjct: 1520 GEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVG----- 1574 Query: 942 SSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPP 1001 L + GP G PGP+G KG +GD G+ G P GP GP G PGPP Sbjct: 1575 ----PLGILGPSGLPGPKGDKGSRGDWGLQG----PRGP-----------PGPRGRPGPP 1615 Query: 1002 GPPGS-ISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSEL 1060 GPPG I ++ +M + SG P P V GE F Sbjct: 1616 GPPGGPIQLQQDDLGAAFQTWMDT-------SGALRPESYSYPDRLVLDQGGEIFKTLHY 1668 Query: 1061 ASHVVSYLRT 1070 S+++ ++T Sbjct: 1669 LSNLIQSIKT 1678 Score = 248 bits (634), Expect = 2e-65 Identities = 148/323 (45%), Positives = 169/323 (52%), Gaps = 43/323 (13%) Query: 561 ENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPM 620 E+G G PGP GD G G +GDRG PG PG P G G QG +G+ G G PG GP Sbjct: 1334 EDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYP---GQEGVQGLRGKPGQQGQPGHPGP- 1389 Query: 621 GQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPG 680 RG GP G +G GP KG++G AG PG G G+ G PGP+G G Sbjct: 1390 --RGWPGPKGSKGAEGP-----KGKQGKAGAPGRRGVQGL---------QGLPGPRGVVG 1433 Query: 681 PVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKG 740 GL+G+ G GLPG G G G G GD G GP G G PG+ GLPGA G PG KG Sbjct: 1434 RQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKG 1493 Query: 741 AMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGK------PGLTGPQGPQGLPGTPG 794 G G G G RG +G TG+PG +G PG G PG PG+ G GP+G PG G Sbjct: 1494 ESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIG 1553 Query: 795 RPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLN 854 GI+G G PG ++ EG + GP G G G PGP G G G GL G Sbjct: 1554 FKGIQGPRGPPG-LMGKEG-----IVGPLGILGPSGLPGPKGDKGSRGDWGLQG------ 1601 Query: 855 LQGPPGPPGPRGPPGPSIPGPPG 877 P GPPGPRG PGP PGPPG Sbjct: 1602 ---PRGPPGPRGRPGP--PGPPG 1619 Score = 241 bits (614), Expect = 5e-63 Identities = 236/780 (30%), Positives = 285/780 (36%), Gaps = 228/780 (29%) Query: 744 PAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPG----------------LTGPQGPQ 787 PA P P G + G + GP P KP T P Q Sbjct: 521 PAVPTPGSAPTGSKKPIGSEASK-KAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQ 579 Query: 788 GLPGTPGRPGIKGEPG---APGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPA 844 P P + P + TS G S+ + G P MGPPGP G G GP Sbjct: 580 PQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPP 639 Query: 845 GLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFL 904 GLPG + +GP GPPGP G PG +PGPPG +G G+ PG + + L Sbjct: 640 GLPGLPGIPGARGPRGPPGPYGNPG--LPGPPGAKGQKGD--PGLSPGKAHDGAKGDMGL 695 Query: 905 SGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGD 964 G G PGPPG KG +G PGP GH GEQG PG S + QG PGP G GPKG Sbjct: 696 PGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGS 755 Query: 965 KGDPGVPGALGIPSG------PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYI 1018 +G G+PG G+P P G M + G PG G GPPG Sbjct: 756 RGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPG------------- 802 Query: 1019 SEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGY----G 1074 L G G G PGPPG V + G+ + L GY G Sbjct: 803 ------------LDGNPGELGLPGPPG-VPGLIGD-----------LGVLGPIGYPGPKG 838 Query: 1075 VSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRI 1134 + S+ L G +G G PG SGD Sbjct: 839 MKGLMGSVGEPG-----------------LKGDKGEQGVPGVSGDPG------------- 868 Query: 1135 LSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWS 1194 + G S GLPG PG G PG L +G +G PGPPGP G PG++ Sbjct: 869 --FQGDKG-SQGLPGFPGARGKPGP--------LGKVGDKGSIGFPGPPGPEGFPGDI-- 915 Query: 1195 SISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYL 1254 GPPG GP G +G PG G R +L Sbjct: 916 --------------------GPPGDNGPEGMKGKPGARGLPGP---------RGQL---- 942 Query: 1255 TSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTG 1314 P+ +GPPG PG +G PG R+G + Sbjct: 943 -GPEGDEGPMGPPGAPGLEGQPG------------------------RKGFPGRPGLDGV 977 Query: 1315 GGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYN 1374 G G G G GE G G G +G G G + GM G G+ G Sbjct: 978 KGEPGDPGRPGPVGEQ-GFMGFIGL-VGEPGIVGEKGDRGMM-GPPGVPGP--------- 1025 Query: 1375 ELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYG 1434 SM G+ GM G PG+PGPQGPPG Sbjct: 1026 ------KGSMGHPGMPGGM-----GTPGEPGPQGPPGS---------------------- 1052 Query: 1435 AIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIA 1494 +GPPG +G KG RGP GP GP G +G +G KG G Q GR ++ +A Sbjct: 1053 --RGPPGMRGA------KGRRGPRGP---DGPAGEQGSRGLKGPPGPQGRPGRPGQQGVA 1101 Score = 188 bits (478), Expect = 3e-47 Identities = 212/753 (28%), Positives = 256/753 (33%), Gaps = 183/753 (24%) Query: 771 PSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAM- 829 P+ PG T P +P T G + P P + GS+ P G + Sbjct: 491 PAPTPGSTRSTRPPATM-VPPTSGTSTPRTAPAVP-----TPGSAPTGSKKPIGSEASKK 544 Query: 830 -GPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPG 888 GP P P P P + +L P P P+ PS P P + L Sbjct: 545 AGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQ----PSQQTTPALVLAPAQFLSS 600 Query: 889 PPGPPGSFLSNSETFLSGP-PGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGL 947 P P S S S P P GPPGPKGD G PGP G G G+PG Sbjct: 601 SPRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPY 660 Query: 948 NLQGPPGPPGPQGPKGD------------KGDPGVPGALGIPSGPSEGGSSSTMYVSGPP 995 G PGPPG +G KGD KGD G+PG G P P G +G P Sbjct: 661 GNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHP 720 Query: 996 GPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETF 1055 G G PGP GS G +G PG G PGPV Sbjct: 721 GEQGQPGPEGS-------------------------PGAKGYPGRQGLPGPVG------- 748 Query: 1056 DYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPG 1115 D S Y+ G LF S G RG PG PG Sbjct: 749 DPGPKGSR--GYIGLPG----LFGLPGSD---------------------GERGLPGVPG 781 Query: 1116 ASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRG 1175 G + R + + +GLPGPPG PGL G G Sbjct: 782 KRGKMGMPGFP-GVFGERGPPGLDGNPGELGLPGPPGVPGLIGDL--------------G 826 Query: 1176 IVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGAL 1235 ++GP G PGP G+ G + S+ L G+ + G PG G G +G PG GA Sbjct: 827 VLGPIGYPGPKGMKG-LMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGAR 885 Query: 1236 ATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSS 1295 + +G PGPPGP+G PGD Sbjct: 886 GKPGPLGKVGDKGS--------------IGFPGPPGPEGFPGDIG--------------- 916 Query: 1296 SHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGM 1355 G + M G G G G G GD GP +GP G G + G Sbjct: 917 ------PPGDNGPEGMKGKPGARGLPGPRGQLGPE-GDEGP----MGPPGAPGLEGQPGR 965 Query: 1356 --YAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGIS 1413 + G GL G V+G PG PG GP G Sbjct: 966 KGFPGRPGLDG--------------------------------VKGEPGDPGRPGPVGEQ 993 Query: 1414 KVFSAYSNVTADLMDFFQTYGAIQGPPG---QKGEMGTPG------PKGDRGPAGPPGHP 1464 V + + + GPPG KG MG PG G+ GP GPPG Sbjct: 994 GFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSR 1053 Query: 1465 GPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 GPPG RG KG +G +G AG + R + P Sbjct: 1054 GPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPP 1086 Score = 163 bits (413), Expect = 1e-39 Identities = 206/766 (26%), Positives = 263/766 (34%), Gaps = 117/766 (15%) Query: 756 EQGLTGMPGIRGPPGPSGDPGKPGLTGPQGP-QGLPGTPGRPGIKGEPGAPGKIVTSEGS 814 E+ + PG+ PP PS P P + + P L T + A + T + Sbjct: 423 EKPIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPP 482 Query: 815 SMLTVPGPPGP-PGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPG--PPGPRGPPGPS 871 + P P PG+ PP P P PG P G + P G Sbjct: 483 PFTALSSSPAPTPGSTRSTRPPATMVP--PTSGTSTPRTAPAVPTPGSAPTGSKKPIGSE 540 Query: 872 IPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGE 931 GP+ P + +P PG + S+ P P P P Sbjct: 541 ASKKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSS 600 Query: 932 QGLPGFSTSGSSSFGLNLQGP-PGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMY 990 P ++SG S F L P P GP GPKGD G PG PG G+P P Sbjct: 601 SPRP--TSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPG--------- 649 Query: 991 VSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTI 1050 GP GPPGP G PG + GPPG G G Sbjct: 650 ARGPRGPPGPYGNPG----------------------------LPGPPGAKGQKGDPGLS 681 Query: 1051 TGETFDYSE-------LASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYL-RQ 1102 G+ D ++ L+ + R G + + + Y RQ Sbjct: 682 PGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQ 741 Query: 1103 YLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGP------PGL 1156 L GP G PGP G+ G Y L L + S GLPG PG PG Sbjct: 742 GLPGPVGDPGPKGSRG--------YIGLPG--LFGLPGSDGERGLPGVPGKRGKMGMPGF 791 Query: 1157 PGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISV-----EDLSSYLHTAGLS 1211 PG E L G+ G +G PGPPG PG+ G++ + + + + + G Sbjct: 792 PGVFGERGPPGLDGNP--GELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEP 849 Query: 1212 FIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPG 1271 + G G G PG G PG G + R + D S +G PGPPG Sbjct: 850 GLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGS--IGFPGPPG 907 Query: 1272 PQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAA 1331 P+G PGD + + RG G G+ G G G Sbjct: 908 PEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKG 967 Query: 1332 --GDRGPYGTDIGPG--GGYGAAAEGGM-----YAGNGGLLGADFAGDLDYNELAVRVSE 1382 G G G PG G G E G G G++G + Sbjct: 968 FPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKG 1027 Query: 1383 SMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQ 1442 SM G+ GM G PG+PGPQGPPG +GPPG Sbjct: 1028 SMGHPGMPGGM-----GTPGEPGPQGPPG------------------------SRGPPGM 1058 Query: 1443 KGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRR 1488 +G G GP+G GPAG G G GP G +G G G Q AG R Sbjct: 1059 RGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGER 1104 Score = 129 bits (323), Expect = 3e-29 Identities = 206/803 (25%), Positives = 260/803 (32%), Gaps = 170/803 (21%) Query: 721 TGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGL 780 T P + LP G G P P Q + + GP P K Sbjct: 274 TATPALGSLPAGRGPRGTVAPATPTKPQRTSPTNPHQHMA----VGGPAQTPLLPAKLSA 329 Query: 781 TGPQGPQGLPGTPGRPGIKGEPGA--PGKIVTSEGSSMLTVPGPPGPPGAMGP-----PG 833 + P LP + G P A P + +T+ P P ++ P P Sbjct: 330 SNALDPM-LPASVGGSTRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPIKSPHPT 388 Query: 834 PPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPP 893 AP + LP ++V P R P P PR PP P PP Sbjct: 389 QKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTS 448 Query: 894 GS-----FLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLN 948 S L+ +E ++ P + PP PG + S Sbjct: 449 SSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRS-------- 500 Query: 949 LQGPPGP--PGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGP--P 1004 PP P G + P VP P+G + S +GP P P P P Sbjct: 501 -TRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPKSSPRKPVPLRP 559 Query: 1005 GSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHV 1064 G + LS + P P P T ++ S Sbjct: 560 GKAARDVP------------------LSDLTTRPSPRQPQPSQQTTPALVLAPAQFLS-- 599 Query: 1065 VSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLS 1124 S R + G S+F + S+ L LMGP GP G Sbjct: 600 -SSPRPTSSGYSIFHLAGSTPFPL---------------LMGPPGPKG------------ 631 Query: 1125 LDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPG 1184 GLPGPPG PGLPG + G+ RG GPPGP G Sbjct: 632 -------------------DCGLPGPPGLPGLPG---------IPGA--RGPRGPPGPYG 661 Query: 1185 PPGIPGNVWSSISVEDLSSYLHTA--------GLSFIPGPPGPPGPPGPRGPPGVSGALA 1236 PG+PG + D A GL + G PGPPG G +G PG +G Sbjct: 662 NPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPG 721 Query: 1237 TYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSS 1296 + SP + + G G PGP G PG SRG Sbjct: 722 EQGQPGPEG----------SPGAKGY-PGRQGLPGPVGDPG--------PKGSRGYIGLP 762 Query: 1297 HSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPG--GGYGAAAEGG 1354 + GS + G G +G G F G+RGP G D PG G G G Sbjct: 763 GLFGL-PGSDGERGLPGVPGKRGKMGMPG-FPGVFGERGPPGLDGNPGELGLPGPPGVPG 820 Query: 1355 MYAGNGGLLGADFAGDLDYNELAVRVSE-----SMQRQGL--------LQGMAYTVQGPP 1401 + G L + G L V E QG+ QG + QG P Sbjct: 821 LIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGS-QGLP 879 Query: 1402 GQPGPQGPPG-ISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGP 1460 G PG +G PG + KV S GPPG +G G GP GD GP G Sbjct: 880 GFPGARGKPGPLGKVGDKGSI-------------GFPGPPGPEGFPGDIGPPGDNGPEGM 926 Query: 1461 PGHPGP---PGPRGHKGEKGDKG 1480 G PG PGPRG G +GD+G Sbjct: 927 KGKPGARGLPGPRGQLGPEGDEG 949 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 468 bits (1205), Expect = e-131 Identities = 372/1066 (34%), Positives = 432/1066 (40%), Gaps = 256/1066 (24%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGI------PGPLGHPGPQGPKGQKGSVGDPGM-- 616 L+G G KG G G +G GFPG PG PGP G GPQG KG G G PG+ Sbjct: 588 LQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPG 647 Query: 617 -----EGPMGQRGREGPMGPRGEAGPPGS----------GEKGERGAAGEPGPHGPPGVP 661 EG G++G GP G +G GPPG+ G G +G G+ G GPPG+P Sbjct: 648 SVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIP 707 Query: 662 GSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLT 721 G +G +G G PG GPPGP G GL GE+G PG G GP GPPG G G GP G Sbjct: 708 GLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTK 767 Query: 722 GEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGL---TGMPGIRGP---------- 768 GEPG RG G G+PG +G +G G G G +GE GL G PG+RG Sbjct: 768 GEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGEL 827 Query: 769 --PGPSGDPGKPGLTGPQGPQGLPGT----------PGRPGIKGE---PGAPGKIVTSEG 813 PG GD G+ G GP GP GLPGT PG G KGE PG PG+ Sbjct: 828 GLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGR 887 Query: 814 SSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPP---GPPGPRGPPG- 869 L GP GPPGA G G GAPG AG G PGH GPP G PG RG PG Sbjct: 888 PGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGK 947 Query: 870 ------------PSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGP- 916 PGP GPRG P G PG PGPPG + E L G PG PGP G Sbjct: 948 DGERGEKGAAGEEGSPGPVGPRGDP--GAPGLPGPPGKG-KDGEPGLRGSPGLPGPLGTK 1004 Query: 917 -------------------KGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPG 957 KGD+G PG G G +G P G+ + GPPGP G Sbjct: 1005 AACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDP----------GIGVAGPPGPSG 1054 Query: 958 PQGPKGDKGDPGVPGALGIPSGPS-EGGSSSTMYVSGPPGPPG----------------- 999 P G KG G G+PG G P GP+ G+ GPPG PG Sbjct: 1055 PPGDKGSPGSRGLPGFPG-PQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDV 1113 Query: 1000 ----PPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETF 1055 PPGPPG G + + + + G GPPG PGPPG I G Sbjct: 1114 CNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEG-KKGEAGPPGLPGPPG----IAGPQG 1168 Query: 1056 DYSEL-ASHVVSYLRTSGY-GVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGP 1113 E A V G+ GV F MGP G PGP Sbjct: 1169 SQGERGADGEVGQKGDQGHPGVPGF--------------------------MGPPGNPGP 1202 Query: 1114 PGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEF 1173 PGA G ++ S G G PGP GP GLPG EE Sbjct: 1203 PGADGIAG---------AAGPPGIQGSPG-KEGPPGPQGPSGLPGIPGEE---------- 1242 Query: 1174 RGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSG 1233 G G G PGPPG PG AG +PGP G GPPG +G G SG Sbjct: 1243 -GKEGRDGKPGPPGEPGK----------------AGEPGLPGPEGARGPPGFKGHTGDSG 1285 Query: 1234 ALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSS 1293 A + + L D + GP GP GP+GPPG + + + Sbjct: 1286 APGPRGESGAMGLPGQ--EGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGT 1343 Query: 1294 SSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAA-----------GDRGPYGT--D 1340 S GS G G G G G+ G+RG G D Sbjct: 1344 PGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGD 1403 Query: 1341 IGPGGGYGAAAEGGM--YAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQ 1398 GP GG G + G+ + G+ GL+G QG L G V Sbjct: 1404 KGPPGGKGQPGDPGIPGHKGHTGLMGP---------------------QG-LPGENGPV- 1440 Query: 1399 GPPGQPGPQGPPGI-----------------------SKVFSAYSNVTADLMDFFQTYGA 1435 GPPG PG G PG+ +++ + + M Q Sbjct: 1441 GPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPG 1500 Query: 1436 IQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGD 1481 GPPG+ G G GP G+ G G G GP GP G KGE+G KGD Sbjct: 1501 PPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGD 1546 Score = 459 bits (1182), Expect = e-129 Identities = 356/999 (35%), Positives = 414/999 (41%), Gaps = 167/999 (16%) Query: 561 ENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKG---QKGSVGDPGME 617 E G+L G PGP G GS G +G+ G G PG+PG +G GPQGP G G VG PG++ Sbjct: 531 EKGSL-GLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQ 589 Query: 618 GPMGQRGREGPMGPRGEAGPPG-------------SGEKGERGAAGEPGPHGPPGVPGSV 664 G G++G G G RG G PG SG G +G G+ GP GPPGVPGSV Sbjct: 590 GERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSV 649 Query: 665 -------------GPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGD 711 GP+G G+PGP G GP+G +G G GL G++G KG MGPPG G Sbjct: 650 VQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGL 709 Query: 712 ---QGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGP 768 QG GP G+ G PG G PG GE G G GP GP G G G G G PG +G Sbjct: 710 LGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGE 769 Query: 769 PGPSGD---PGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGP 825 PG G+ PGKPGL G G QGL G PG G G PGAPG G G Sbjct: 770 PGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGL 829 Query: 826 PGAMGPPGPPGAPGPAGPAGLPGHQEVLN----LQGPPGPPGPRGPPGPSIPGPPGPRGP 881 PG G G G GPAGP GLPG + + G GP G +G PG +PG PG +G Sbjct: 830 PGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPG--LPGEPGLQGR 887 Query: 882 PGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTS 940 PGE G GP GPPG+ G G PG PG G GP GP G G GL G Sbjct: 888 PGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGK 947 Query: 941 GSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGP 1000 G G PGP GP+GD G PG+PG P G + G + G PG PGP Sbjct: 948 DGERGEKGAAGEEGSPGPVGPRGDPGAPGLPG----PPGKGKDGEPG---LRGSPGLPGP 1000 Query: 1001 PGPPGSISS-SGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPG-----PPGPVTTITGET 1054 G + G E + ++ D + G G G PG PPGP +G Sbjct: 1001 LGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGP----SGPP 1056 Query: 1055 FDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPP 1114 D S G+ F RD G RGPPG P Sbjct: 1057 GDKGSPGSR----------GLPGFPGPQGPAG------RDGAPGN-----PGERGPPGKP 1095 Query: 1115 GAS-----GDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLR 1169 G S GD +LL+ D PGPPG PGLPG ++ + Sbjct: 1096 GLSSLLSPGDINLLAKDVCNDCP---------------PGPPGLPGLPGFKGDKGVPGKP 1140 Query: 1170 GSEF----RGIVGPPGPPGPPGIPGNVWSS--ISVEDLSSYLHTAGLSFIPGPPGPPGPP 1223 G E +G GPPG PGPPGI G S + G +PG GPPG P Sbjct: 1141 GREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNP 1200 Query: 1224 GPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLS 1283 GP G G++GA + S G GPPGPQGP G + Sbjct: 1201 GPPGADGIAGAAGPPGIQGSP--------------------GKEGPPGPQGPSGLPGIPG 1240 Query: 1284 TDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGT---- 1339 + R + G G G G G G A G RG G Sbjct: 1241 EEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSG-APGPRGESGAMGLP 1299 Query: 1340 ----------DIGPGGGYGAAAEGGMYAGNG--GLLGADFAGDLDYNELAVRVSESMQRQ 1387 D GP G G G NG G G + + + S Sbjct: 1300 GQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLP 1359 Query: 1388 GLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMG 1447 G L +GPPG+PG +G PG V G PG KGE G Sbjct: 1360 GFLGP-----RGPPGEPGEKGVPGKEGVPGK------------------PGEPGFKGERG 1396 Query: 1448 TPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 PG KGD+GP G G PG PG GHKG G G Q G Sbjct: 1397 DPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPG 1435 Score = 448 bits (1153), Expect = e-125 Identities = 342/972 (35%), Positives = 404/972 (41%), Gaps = 215/972 (22%) Query: 570 GPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPM 629 G KG+MG GP G G G G GP+G P GPKG+KG VG GP GQ G +G Sbjct: 481 GEKGEMGVAGPMGLPGPKGDIGAIGPVGAP---GPKGEKGDVG----IGPFGQ-GEKGEK 532 Query: 630 GPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRG 689 G G GPP G G +G GEPG G PG+PG VG +G G PG GPPG VG GL+G Sbjct: 533 GSLGLPGPP--GRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQG 590 Query: 690 EVGLPGVKGDKGPM------GPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAM- 742 E G G +G+KG G PG G QG GP G+ G G +G G G PG G++ Sbjct: 591 ERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVV 650 Query: 743 ---GPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIK 799 G G G GPRG QG G PG RGP GP G G PGL G +G +G G PG PG+ Sbjct: 651 QQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLL 710 Query: 800 GEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPP 859 G + GPPGPPG GPPGP G+PG G G PG GPP Sbjct: 711 G------------------LQGPPGPPGVPGPPGPGGSPGLPGEIGFPGK------PGPP 746 Query: 860 GPPGPRGPPGPS-IPGPPGPRGPPGE----GLPGPPGPPGSFLSNSETFLSGPPGP---- 910 GP GP G GP+ PGPPG +G PGE GLPG PG G E L+G PG Sbjct: 747 GPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEI---GEQGLAGRPGEKGEA 803 Query: 911 --PGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPG-------------P 955 PG PG G +G G +G +GE GLPG GPPG Sbjct: 804 GLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRM 863 Query: 956 PGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQ 1015 PG QGPKG+KGDPG+PG G+ P E GP GP GPPG G + G Sbjct: 864 PGEQGPKGEKGDPGLPGEPGLQGRPGE---------LGPQGPTGPPGAKGQEGAHG---- 910 Query: 1016 QYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGV 1075 + G G PGP GPPG V T G Sbjct: 911 ------APGAAGNPGAPGHVGAPGPSGPPGSV---------------GAPGLRGTPGKDG 949 Query: 1076 SLFSSSISSEDIL--AVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSR 1133 + E+ V R D G G PGPPG DG L Sbjct: 950 ERGEKGAAGEEGSPGPVGPRGD---------PGAPGLPGPPGKGKDGEPGLRGSPGLPGP 1000 Query: 1134 ILS------YMSSSGISIG---LPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPG 1184 + + S ++G + G G PG+PG+ RG G+ GPPGP G Sbjct: 1001 LGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGS------RGDPGIGVAGPPGPSG 1054 Query: 1185 PPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGP------PGPPGPRGPPGVSGALATY 1238 PPG G+ S GL PGP GP PG PG RGPPG G + Sbjct: 1055 PPGDKGSPGS-------------RGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLL 1101 Query: 1239 AAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHS 1298 + + + ++ + PPGPPG G PG R + Sbjct: 1102 SPGDINLLAKDVCNDC-----------PPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKG 1150 Query: 1299 SSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTD--IGPGGGYGAAAEGGMY 1356 + G ++ G G GA G G+ GD+G G +GP G G G+ Sbjct: 1151 EAGPPGLPGPPGIAGPQGSQGERGADGEVGQ-KGDQGHPGVPGFMGPPGNPGPPGADGI- 1208 Query: 1357 AGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVF 1416 AG G G +QG PG+ GP GP G S + Sbjct: 1209 AGAAGPPG--------------------------------IQGSPGKEGPPGPQGPSGL- 1235 Query: 1417 SAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEK 1476 I G G++G G PGP G+ G AG PG PGP G RG G K Sbjct: 1236 -----------------PGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFK 1278 Query: 1477 GDKGDQVYAGRR 1488 G GD G R Sbjct: 1279 GHTGDSGAPGPR 1290 Score = 404 bits (1037), Expect = e-112 Identities = 301/828 (36%), Positives = 341/828 (41%), Gaps = 205/828 (24%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLG----------HPGPQGPKGQKGSVGDPG 615 +G G KG++G PG KGDRG G G GP G HP G +G KG GDPG Sbjct: 818 KGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPG 877 Query: 616 MEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGP 675 + G G +GR G +GP+G GPPG+ KG+ GA G PG G PG PG VG G SG PG Sbjct: 878 LPGEPGLQGRPGELGPQGPTGPPGA--KGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGS 935 Query: 676 QGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGD-----------QGEKGPRGLTGEP 724 G PG G G GE G G G++G GP GP+GD +G+ G GL G P Sbjct: 936 VGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSP 995 Query: 725 GM-----------------------------RGLPGAVGEPGAKG--------AMGPAGP 747 G+ RG PG G PG++G GP+GP Sbjct: 996 GLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGP 1055 Query: 748 DGHQGPRGEQGLTGMPGIRGP---------PGPSGDPGKPGLTG---------------- 782 G +G G +GL G PG +GP PG G PGKPGL+ Sbjct: 1056 PGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCN 1115 Query: 783 --PQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPG---A 837 P GP GLPG PG G KG PG PG+ T PG PGPPG GP G G A Sbjct: 1116 DCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGA 1175 Query: 838 PGPAGPAGLPGHQEVLNLQGPPGPPGP---------RGPPG----PSIPGPPGPRGPPG- 883 G G G GH V GPPG PGP GPPG P GPPGP+GP G Sbjct: 1176 DGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGL 1235 Query: 884 ---------EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKG---DQGPPGPRGHQGE 931 EG G PGPPG E L GP G GPPG KG D G PGPRG G Sbjct: 1236 PGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGA 1295 Query: 932 QGLPGFSTSGSSSFGLNLQGPPGPPGPQGP------------------------KGDKGD 967 GLPG GP GP GP+GP KG+ G Sbjct: 1296 MGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGS 1355 Query: 968 PGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPG---------------PPGSISSSGQ 1012 PG+PG LG P E G G PG PG PG PPG GQ Sbjct: 1356 PGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGG---KGQ 1412 Query: 1013 EIQQYISEYMQSDSIRSY--LSGVQGPPGPPGPPGP--VTTITGETFDYSELASHVVSYL 1068 I + + L G GP GPPGPPG + GE+ L + L Sbjct: 1413 PGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEEL 1472 Query: 1069 RTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYA 1128 G L E LA L + Q Y+ +G PGPPG G L Sbjct: 1473 -----GKQL-------ETRLAYL----LAQMPPAYMKSSQGRPGPPGPPGKDGLPG---- 1512 Query: 1129 ELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGI 1188 + + G GL GP GP G G + G RG +GPPG PG PG Sbjct: 1513 --RAGPMGEPGRPGQG-GLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGE 1569 Query: 1189 PGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGP------PGPRGPPG 1230 PG GL IPGP G GP PGP GPPG Sbjct: 1570 PGYA--------------KDGLPGIPGPQGETGPAGHPGLPGPPGPPG 1603 Score = 402 bits (1034), Expect = e-111 Identities = 299/874 (34%), Positives = 353/874 (40%), Gaps = 224/874 (25%) Query: 559 EQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGP-------------- 604 E+ L G+PG G G G +G++G G PG+ G G G GP Sbjct: 799 EKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFT 858 Query: 605 --------KGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHG 656 +G KG GDPG+ G G +GR G +GP+G GPPG+ KG+ GA G PG G Sbjct: 859 PHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGA--KGQEGAHGAPGAAG 916 Query: 657 PPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGD----- 711 PG PG VG G SG PG G PG G G GE G G G++G GP GP+GD Sbjct: 917 NPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPG 976 Query: 712 ------QGEKGPRGLTGEPGM-----------------------------RGLPGAVGEP 736 +G+ G GL G PG+ RG PG G P Sbjct: 977 LPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSP 1036 Query: 737 GAK--------GAMGPAGPDGHQGPRGEQGLTGMPGIRGP---------PGPSGDPGKPG 779 G++ G GP+GP G +G G +GL G PG +GP PG G PGKPG Sbjct: 1037 GSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPG 1096 Query: 780 LTG------------------PQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPG 821 L+ P GP GLPG PG G KG PG PG+ T PG Sbjct: 1097 LSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPG 1156 Query: 822 PPGPPGAMGPPGPP---GAPGPAGPAGLPGHQEVLNLQGPPGPPGP---------RGPPG 869 PGPPG GP G GA G G G GH V GPPG PGP GPPG Sbjct: 1157 LPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPG 1216 Query: 870 ----PSIPGPPGPRGPPG----------EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPG 915 P GPPGP+GP G EG G PGPPG E L GP G GPPG Sbjct: 1217 IQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG 1276 Query: 916 PK---GDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPG 972 K GD G PGPRG G GLPG GP GP GP+GP G G PG PG Sbjct: 1277 FKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPG 1336 Query: 973 ALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSY-- 1030 G P + GS G PG GP GPPG G ++ + + Sbjct: 1337 EPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERG 1396 Query: 1031 ---LSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDI 1087 + G +GPPG G PG I G G+ + + E+ Sbjct: 1397 DPGIKGDKGPPGGKGQPGD-PGIPGH-----------------KGHTGLMGPQGLPGEN- 1437 Query: 1088 LAVLQRDDVRQYLRQYLMGPRGPPGPPGASG----DGSLLSLDY----------AELSSR 1133 GP GPPGPPG G G S++ +L +R Sbjct: 1438 ------------------GPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETR 1479 Query: 1134 IL--------SYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGP 1185 + +YM SS G PGPPGPPG G G GP G PG Sbjct: 1480 LAYLLAQMPPAYMKSSQ---GRPGPPGPPGKDG--------------LPGRAGPMGEPGR 1522 Query: 1186 PGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGP--PGPRGPPGVSGALATYAAENS 1243 PG G +E S + G G PG PG G GPPG+ G Sbjct: 1523 PGQGG-------LEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPG------QPGE 1569 Query: 1244 DSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPG 1277 + + + + P + G PG PGP GPPG Sbjct: 1570 PGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPG 1603 Score = 385 bits (990), Expect = e-106 Identities = 280/744 (37%), Positives = 326/744 (43%), Gaps = 167/744 (22%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGR 625 RG G G+ GSPGP G RG PG PG+PGP G +G G+ G G PG+ GP+G + Sbjct: 951 RGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG----KGKDGEPGLRGSPGLPGPLGTKAA 1006 Query: 626 EGPM--------------GPRGEAGPPGS-GEKGERG--AAGEPGPHGPPGVPGSVGPKG 668 G + G RG G PGS G +G+ G AG PGP GPPG GS G +G Sbjct: 1007 CGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRG 1066 Query: 669 SSGSPGPQGPPGPVGLQGLRGE------------------------------------VG 692 G PGPQGP G G G GE G Sbjct: 1067 LPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPG 1126 Query: 693 LPGVKGDKGPMGPPGPKGDQGEKG---PRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDG 749 LPG KGDKG G PG +G +G+KG P GL G PG+ G G+ GE GA G +G G G Sbjct: 1127 LPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQG 1186 Query: 750 HQGPRGEQGLTGMPG---------IRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKG 800 H G G G G PG GPPG G PGK G GPQGP GLPG PG G +G Sbjct: 1187 HPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEG 1246 Query: 801 EPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPG------PPGAPGPAGPAG---LPGHQE 851 G PG PG PGP GA GPPG GAPGP G +G LPG + Sbjct: 1247 RDGKPGP---PGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEG 1303 Query: 852 VLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPG- 909 + G GP GP+GP GP GPPG G PG G PGP G PG S E G PG Sbjct: 1304 LPGKDGDTGPTGPQGPQGPR--GPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGF 1361 Query: 910 --PPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGD 967 P GPPG G++G PG G G+ G PGF ++G GPPG +G GD G Sbjct: 1362 LGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDP---GIKGDKGPPGGKGQPGDPGI 1418 Query: 968 PGVPGALGI--PSG-PSEGGSSSTMYVSGPPGPPGPPGPPG--SISSSGQEIQQYISE-- 1020 PG G G+ P G P E G GPPGPPG PG PG S S + +++ I E Sbjct: 1419 PGHKGHTGLMGPQGLPGENGPV------GPPGPPGQPGFPGLRGESPSMETLRRLIQEEL 1472 Query: 1021 ---------YMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTS 1071 Y+ + +Y+ QG PGPPGPPG + G E R Sbjct: 1473 GKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGK-DGLPGRAGPMGEPG-------RPG 1524 Query: 1072 GYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELS 1131 G+ S I + G RG G PGA G G + Sbjct: 1525 QGGLEGPSGPIGPK--------------------GERGAKGDPGAPGVGLRGEM------ 1558 Query: 1132 SRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGN 1191 G PG PG PG PG + + L + G G PG PGPPG PG Sbjct: 1559 --------------GPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604 Query: 1192 VWSSISVEDLSSYLHTAGLSFIPG 1215 D S + A L+ PG Sbjct: 1605 C-------DPSQCAYFASLAARPG 1621 Score = 340 bits (871), Expect = 8e-93 Identities = 214/522 (40%), Positives = 245/522 (46%), Gaps = 111/522 (21%) Query: 565 LRGSPGPKGDMGSPGP------KGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEG 618 L G PG KGD G PG +G +G G PG+PGP G GPQG +G++G+ G+ G +G Sbjct: 1124 LPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKG 1183 Query: 619 PMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPG---- 674 G G G MGP G GPPG+ G GAAG PG G PG G GP+G SG PG Sbjct: 1184 DQGHPGVPGFMGPPGNPGPPGAD--GIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGE 1241 Query: 675 -----PQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGL 729 G PGP G G GE GLPG +G +GP G G GD G GPRG E G GL Sbjct: 1242 EGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRG---ESGAMGL 1298 Query: 730 PGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGK---------PGL 780 PG G PG G GP GP G QGPRG G G PG G PGPSG PG+ PGL Sbjct: 1299 PGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGL 1358 Query: 781 TGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPG------PPGAMGPPGP 834 G GP+G PG PG G+ G+ G PGK PG PG PG G GP Sbjct: 1359 PGFLGPRGPPGEPGEKGVPGKEGVPGK------------PGEPGFKGERGDPGIKGDKGP 1406 Query: 835 PGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPG----------- 883 PG G G G+PGH+ L GP G PG GP GP PGPPG G PG Sbjct: 1407 PGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGP--PGPPGQPGFPGLRGESPSMETL 1464 Query: 884 -------------------------------EGLPGPPGPPGSFLSNSETFLSGPPGPPG 912 +G PGPPGPPG + +GP G PG Sbjct: 1465 RRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGK---DGLPGRAGPMGEPG 1521 Query: 913 PPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQ-GPPGPPGPQG----------- 960 PG G +GP GP G +GE+G G G+ GL + GPPG PG G Sbjct: 1522 RPGQGGLEGPSGPIGPKGERGAKG--DPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPG 1579 Query: 961 ---PKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPG 999 P+G+ G G PG G P P + S Y + PG Sbjct: 1580 IPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPG 1621 Score = 321 bits (823), Expect = 3e-87 Identities = 203/493 (41%), Positives = 237/493 (48%), Gaps = 109/493 (22%) Query: 559 EQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEG 618 +Q + + G GP G+ G PG G G G PGI G G GP GP+G G G PG EG Sbjct: 1184 DQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG 1243 Query: 619 PMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGP 678 G+ G+ GP G G+AG PG PGP G G PG G G SG+PGP+G Sbjct: 1244 KEGRDGKPGPPGEPGKAGEPGL-----------PGPEGARGPPGFKGHTGDSGAPGPRGE 1292 Query: 679 PGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGA 738 G +GL G+ GLPG GD GP GP GP QG +GP PG G PG+ GEPG Sbjct: 1293 SGAMGLP---GQEGLPGKDGDTGPTGPQGP---QGPRGP------PGKNGSPGSPGEPG- 1339 Query: 739 KGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGI 798 P+G G +G +GE G G+PG GP GP PG+PG G G +G+PG PG PG Sbjct: 1340 -----PSGTPGQKGSKGENGSPGLPGFLGPRGP---PGEPGEKGVPGKEGVPGKPGEPGF 1391 Query: 799 KGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGP 858 KGE G PG + G GPPG G PG PG PG G GL G Q L G Sbjct: 1392 KGERGDPG------------IKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQ---GLPGE 1436 Query: 859 PGPPGPRGPPGPSIPGPPGPRG-------------------------------PP----- 882 GP GP GPPG PG PG RG PP Sbjct: 1437 NGPVGPPGPPGQ--PGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKS 1494 Query: 883 GEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGS 942 +G PGPPGPPG G PG PG G +G GP GP+G +G +G PG Sbjct: 1495 SQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPG------ 1548 Query: 943 SSFGLNLQGPPGPPGPQGPKGDKGD-----PGVPGALGIPSGPSEGGSSSTMYVSGPPGP 997 + G+ L+G GPPG G G+ G PG+PG G +GP +G PG Sbjct: 1549 -APGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQG-ETGP-----------AGHPGL 1595 Query: 998 PGPPGPPGSISSS 1010 PGPPGPPG S Sbjct: 1596 PGPPGPPGQCDPS 1608 Score = 211 bits (537), Expect = 4e-54 Identities = 204/709 (28%), Positives = 251/709 (35%), Gaps = 233/709 (32%) Query: 815 SMLTVPGPPGPP-----------------GAMGPPGPPGAPGPAGPAGLPGHQEVLNLQG 857 +++T P PP PP P G G G AGP GLPG + + G Sbjct: 446 TVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIG 505 Query: 858 PPGPPGPRGPPGPSIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGP 916 P G PGP+G G GP G +G GE G G PGPPG G G G PG Sbjct: 506 PVGAPGPKGEKGDVGIGPFG-QGEKGEKGSLGLPGPPGR---------DGSKGMRGEPGE 555 Query: 917 KGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPG---PPGPQGPKGDKGDPGVPGA 973 G+ G PG G +G QG PG L GPPG PG QG +G+KG G G Sbjct: 556 LGEPGLPGEVGMRGPQGPPG------------LPGPPGRVGAPGLQGERGEKGTRGEKGE 603 Query: 974 LGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSG 1033 G+ P + G + G PGP G GP G G Sbjct: 604 RGLDGFPGKPGDTGQQ---GRPGPSGVAGPQGE-------------------------KG 635 Query: 1034 VQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQR 1093 GP GPPG PG +V+Q+ Sbjct: 636 DVGPAGPPGVPG-------------------------------------------SVVQQ 652 Query: 1094 DDVRQYLRQYLMGPR---GPPGPPGASGDGSLLSLDYAELSSRILSY---MSSSGIS--I 1145 + ++ Q GPR G PGPPGA G D + M GI + Sbjct: 653 EGLKG--EQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLL 710 Query: 1146 GLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYL 1205 GL GPPGPPG+P GPPGP G PG+PG + Sbjct: 711 GLQGPPGPPGVP--------------------GPPGPGGSPGLPGEI------------- 737 Query: 1206 HTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVG 1265 G PG PGPPGP GPPG G P+ G Sbjct: 738 ---------GFPGKPGPPGPTGPPGKDG-----------------------PN------G 759 Query: 1266 PPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGG 1325 PPGPPG +G PG+ + R G + + G G G G Sbjct: 760 PPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKG 819 Query: 1326 AFGEAA--------GDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELA 1377 GE GDRG G + GP G G ++ + + G + Sbjct: 820 DQGEKGELGLPGLKGDRGEKG-EAGPAGPPGLPGTTSLFTPHPRMPG-------EQGPKG 871 Query: 1378 VRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQ 1437 + + + LQG G G GP GPPG A+ Sbjct: 872 EKGDPGLPGEPGLQGR----PGELGPQGPTGPPGAKGQEGAH------------------ 909 Query: 1438 GPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 G PG G G PG G GP+GPPG G PG RG G+ G++G++ AG Sbjct: 910 GAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAG 958 Score = 199 bits (507), Expect = 1e-50 Identities = 201/716 (28%), Positives = 245/716 (34%), Gaps = 226/716 (31%) Query: 809 VTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGP-----------AGPAGLPGHQEVLNLQG 857 + S + V PP PP PP P PG + PAG G V G Sbjct: 438 IPSGPCQVTVVTEPPPPP----PPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMG 493 Query: 858 PPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPK 917 PGP G G GP G PGP+G G+ GP G E G G PGPPG Sbjct: 494 LPGPKGDIGAIGPV--GAPGPKGEKGDVGIGPFG-------QGEKGEKGSLGLPGPPGRD 544 Query: 918 GDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIP 977 G +G G G GE GLPG + ++GP GPPG GP G G PG+ G G Sbjct: 545 GSKGMRGEPGELGEPGLPG---------EVGMRGPQGPPGLPGPPGRVGAPGLQGERGEK 595 Query: 978 SGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGP 1037 E G G PG G G PG +G + ++ G GP Sbjct: 596 GTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEK----------------GDVGP 639 Query: 1038 PGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVR 1097 GPPG PG +V+Q++ ++ Sbjct: 640 AGPPGVPG-------------------------------------------SVVQQEGLK 656 Query: 1098 QYLRQYLMGPRG---PPGPPGASGDGSLLSLDYAELSSRILSY---MSSSGIS--IGLPG 1149 Q GPRG PGPPGA G D + M GI +GL G Sbjct: 657 G--EQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQG 714 Query: 1150 PPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAG 1209 PPGPPG+PG PPGP G PG+PG + Sbjct: 715 PPGPPGVPG--------------------PPGPGGSPGLPGEI----------------- 737 Query: 1210 LSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGP 1269 G PG PGPPGP GPPG G P+ GPPGP Sbjct: 738 -----GFPGKPGPPGPTGPPGKDG-----------------------PN------GPPGP 763 Query: 1270 PGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGE 1329 PG +G PG+ + R G + + G G G G GE Sbjct: 764 PGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGE 823 Query: 1330 AA--------GDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVS 1381 GDRG G + GP G G ++ + + G + + Sbjct: 824 KGELGLPGLKGDRGEKG-EAGPAGPPGLPGTTSLFTPHPRMPG-------EQGPKGEKGD 875 Query: 1382 ESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPG 1441 + + LQG PG+ GPQGP G PPG Sbjct: 876 PGLPGEPGLQGR-------PGELGPQGPTG---------------------------PPG 901 Query: 1442 QKGEMGTPGPKGDRGPAGPPGH---PGPPGPRGHKGEKGDKGDQVYAGRRRRRSIA 1494 KG+ G G G G G PGH PGP GP G G G +G G R + A Sbjct: 902 AKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAA 957 Score = 116 bits (291), Expect = 1e-25 Identities = 83/232 (35%), Positives = 93/232 (40%), Gaps = 61/232 (26%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMG---- 621 RG PG KGD G PG KG G PG PG G G GPQG G+ G VG PG G G Sbjct: 1395 RGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGL 1454 Query: 622 ----------------------------------------QRGREGPMGPRGEAGPPGS- 640 +GR GP GP G+ G PG Sbjct: 1455 RGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRA 1514 Query: 641 ---GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGP--QGPPGPVGLQGLRGEVG--- 692 GE G G G GP GP G G G KG G+PG +G GP G+ G GE G Sbjct: 1515 GPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAK 1574 Query: 693 --LPGVKGDKGPMGP------PGPKGDQGEKGPRGLTGEPGMRGLPGAVGEP 736 LPG+ G +G GP PGP G G+ P + PG V P Sbjct: 1575 DGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1626 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 454 bits (1167), Expect = e-127 Identities = 359/973 (36%), Positives = 416/973 (42%), Gaps = 127/973 (13%) Query: 567 GSPGPKGDMGSPGPKGDRGFPG---TPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQR 623 G G KG G+PG KG+ G PG TPG G G PG +G G G G G +G +G Sbjct: 184 GLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGP- 242 Query: 624 GREGPMGPRGEAGPPG----SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPP 679 GP GP G AGPPG G KGE GA G GP GP G G VG G SG GP G P Sbjct: 243 --VGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNP 300 Query: 680 GPVGLQGLRGEVGLPGVKGD---KGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEP 736 G GL G +G GLPGV G GP G PGP G G G RGL GEPG G G G Sbjct: 301 GANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNK 360 Query: 737 GAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRP 796 G G+ GP GP G G G++G G G GPPGP PGL G G +GLPG GR Sbjct: 361 GEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGP------PGLRGSPGSRGLPGADGRA 414 Query: 797 GIKGEPGAPGKIVTSEGSSMLTVP----GPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEV 852 G+ G PG+ G + G + + P G PG PG MGP G PG+PG GPAG G + Sbjct: 415 GVMGPPGSRG----ASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGL 470 Query: 853 LNLQGPPGPPGP---RGPPGP-SIPGPPGPRGPPGE-------GLPGPPGPPGSFLSNSE 901 + G PGP GP RG PG PGP GP G PG+ GL G G PG +N Sbjct: 471 PGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNG- 529 Query: 902 TFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGP 961 GPPGP G G KG+QGPPGP G QG G G + L G G PGP GP Sbjct: 530 --AQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGP 587 Query: 962 KGDKGDPGVPGALGI--------PSGP-------SEGGSSSTMYVSGPPGPPGPPGPPGS 1006 +G++G PG GA G PSGP E G + +GP GP G PG G+ Sbjct: 588 RGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGA 647 Query: 1007 ISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVS 1066 G + ++ ++ + G +G PG G PGP G T D E + Sbjct: 648 AGIPGGKGEKG-EPGLRGEIGNPGRDGARGAPGAVGAPGP----AGATGDRGEAGA---- 698 Query: 1067 YLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLD 1126 +G S +R +V GP G G PGA G+ Sbjct: 699 -AGPAGPAGPRGSPG----------ERGEVGPAGPNGFAGPAGAAGQPGAKGERG----- 742 Query: 1127 YAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPP 1186 A+ + +G +G GP GP G PG + GS RG GPPG G P Sbjct: 743 -AKGPKGENGVVGPTG-PVGAAGPAGPNGPPGPA---------GS--RGDGGPPGMTGFP 789 Query: 1187 GIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPP------GPRGPPGVSGALATYAA 1240 G G G S I GPPGPPGP GPRG G G A Sbjct: 790 GAAGRT-------------GPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGA 836 Query: 1241 ENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASH-SRGSSSSSHSS 1299 F E P + GPPG PGPQG G +L S RG + + Sbjct: 837 VGPPGFAGE-----KGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAV 891 Query: 1300 SVRRGSSYSSSMSTGG--GGAGSLGAGGAFGEAAGDRGPYGTDIGPG--GGYGAAAEGGM 1355 + G G GS G GA GEA D P G D PG G G E G Sbjct: 892 GEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNP-GNDGPPGRDGQPGHKGERG- 949 Query: 1356 YAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKV 1415 Y GN G +GA AG + + R G G GP GP GI Sbjct: 950 YPGNIGPVGA--AGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGD 1007 Query: 1416 FSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGE 1475 + + + +QG PG G G G G GPAGP G GP GP G G Sbjct: 1008 KGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGR 1067 Query: 1476 KGDKGDQVYAGRR 1488 G G AG R Sbjct: 1068 TGHPGTVGPAGIR 1080 Score = 450 bits (1157), Expect = e-126 Identities = 347/963 (36%), Positives = 412/963 (42%), Gaps = 122/963 (12%) Query: 565 LRGSPGPKGDMGSPGPKGDRG---FPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMG 621 L G GP G G+PGP+G +G PG PG GP G GP GP G+ G G PG G G Sbjct: 95 LMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPG 154 Query: 622 QRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPG 680 +RG GP G RG G PG G KG RG G G G PG PG KG G+PG G PG Sbjct: 155 ERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGV---KGEPGAPGENGTPG 211 Query: 681 PVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKG 740 G +GL GE G G G G G G G G GP G G PG G PG GE GA G Sbjct: 212 QTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVG 271 Query: 741 AMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKG 800 GPAGP GPRGE GL PG+ GP GP G+PG GLTG +G GLPG G PG+ G Sbjct: 272 NAGPAGP---AGPRGEVGL---PGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPG 325 Query: 801 EPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPG 860 G PG + + + + G PGP G+ G G G PG AGP G PG +GP G Sbjct: 326 PRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNG 385 Query: 861 PPGPRGPPG-PSIPGPPGPRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKG 918 G GPPG P + G PG RG PG +G G GPPGS G GP G GP G Sbjct: 386 EAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGS---------RGASGPAGVRGPNG 436 Query: 919 DQGPPGPRGHQGEQGLPG----FSTSGSSS-FGL-NLQGPPGPPGPQGPKGDKGDPGVPG 972 D G PG G G +GLPG +G GL + G PGP GP G +G+ G+ G PG Sbjct: 437 DAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPG 496 Query: 973 ALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLS 1032 G P + G ++G G PGP G G+ G + Q Sbjct: 497 PKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQ-------------GGK 543 Query: 1033 GVQGPPGP------PGPPGPVTTI--TGETFDYSELASHVVSYLR-----TSGYGVSLFS 1079 G QGPPGP PGP GP + GE + E + R G + + Sbjct: 544 GEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPT 603 Query: 1080 SSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMS 1139 I S GP GPPGP G G+ ++ Sbjct: 604 GPIGSR--------------------GPSGPPGPDGNKGEPGVVG--------------- 628 Query: 1140 SSGISIGLPGPPGPPGLPGTSYEELLSLLRGSE----FRGIVGPPGPPGPPGIPGNVWSS 1195 ++G GP GP GLPG + +G + RG +G PG G G PG V + Sbjct: 629 ----AVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAV-GA 683 Query: 1196 ISVEDLSSYLHTAGLSFIPGPPGPPGPPGPR---GPPGVSGALATYAAENSDSFRSELIS 1252 + AG + GP GP G PG R GP G +G A + E Sbjct: 684 PGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGE--R 741 Query: 1253 YLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRG---SSSSSHSSSVRRGSSYSS 1309 P + +VGP GP G GP G + S G + ++ R G S Sbjct: 742 GAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPS 801 Query: 1310 SMSTGGGGAGSLGAGGAFGEAAGDRGPYGT--DIGPGGGYGAAAEGGM--YAGNGGLLGA 1365 +S G G G G G GD+GP G ++G G G A E G AG G G Sbjct: 802 GISGPPGPPGPAGKEGLRG-PRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGT 860 Query: 1366 DFAGDLDYNELAVRVSESMQRQGLLQGMAYTV--------QGPPGQPGPQGPPGISKVFS 1417 L + + S +G L G+A V GPPG GP G G V Sbjct: 861 PGPQGLLGAPGILGLPGSRGERG-LPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNG 919 Query: 1418 AYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKG 1477 A D G PG KGE G PG G G AG PG GP GP G G +G Sbjct: 920 APGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRG 979 Query: 1478 DKG 1480 + G Sbjct: 980 ETG 982 Score = 441 bits (1133), Expect = e-123 Identities = 342/985 (34%), Positives = 415/985 (42%), Gaps = 175/985 (17%) Query: 562 NGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDP---GMEG 618 N G GP+G++G PG G G PG PG G G G G G G+ G P G+ G Sbjct: 272 NAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPG 331 Query: 619 PMGQRGREGPMGPRGEAGPPGS-GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQG 677 P+G G G G GE GP GS GE G +G G GP GPPG G G +G +G G G Sbjct: 332 PVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAG 391 Query: 678 PPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPG 737 PPGP GL+G G GLPG G G MGPPG +G G G RG G+ G G PG +G G Sbjct: 392 PPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRG 451 Query: 738 AKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLP---GTPG 794 G+ G GP G +GP G G+ G PG GP G G+PG G GP+GP G P G G Sbjct: 452 LPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKG 511 Query: 795 RPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGA------MGPPGPP---GAPGPAGPA- 844 G+ G GAPG +G++ GPPGP G GPPGPP G PGP+GPA Sbjct: 512 HAGLAGARGAPG----PDGNN--GAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAG 565 Query: 845 --GLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSE 901 G PG + + G PGP GPRG GP PG G GP G G GP GPPG + E Sbjct: 566 EVGKPGERGLHGEFGLPGPAGPRGERGP--PGESGAAGPTGPIGSRGPSGPPGPDGNKGE 623 Query: 902 TFL------SGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGP 955 + +GP GP G PG +G G PG +G +GE GL G + G G Sbjct: 624 PGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGA 683 Query: 956 PGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQ 1015 PGP G GD+G+ G G G P+GP GS GP GP G GP G+ G + + Sbjct: 684 PGPAGATGDRGEAGAAGPAG-PAGPR--GSPGERGEVGPAGPNGFAGPAGAAGQPGAKGE 740 Query: 1016 QYISEYMQSDSIRSYLS--GVQGPPGPPGPPGPVTTITGETFDYSE--LASHVVSYLRTS 1071 + + + G GP GP GPPGP G D + + RT Sbjct: 741 RGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGP----AGSRGDGGPPGMTGFPGAAGRTG 796 Query: 1072 GYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGD-GSLLSLDYAEL 1130 G S S ++ L GPRG GP G +G+ G++ +A Sbjct: 797 PPGPSGISGPPGPPGPAG-----------KEGLRGPRGDQGPVGRTGEVGAVGPPGFAGE 845 Query: 1131 SSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPG 1190 S + G PG PGP GL G GI+G PG G G+PG Sbjct: 846 KG-----PSGEAGTAGPPGTPGPQGLLGAP--------------GILGLPGSRGERGLPG 886 Query: 1191 NVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSEL 1250 AG PGP G GPPG RGPPG G Sbjct: 887 ----------------VAGAVGEPGPLGIAGPPGARGPPGAVG----------------- 913 Query: 1251 ISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSS 1310 SP V G PG G G PG+ D R G+ Sbjct: 914 -----SPGVN----GAPGEAGRDGNPGN------DGPPGRDGQPGHKGERGYPGNIGPVG 958 Query: 1311 MSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYA--GNGGLLGADFA 1368 + G G +G G G G+ GP G +GP G G G G+ G G Sbjct: 959 AAGAPGPHGPVGPAGKHGN-RGETGPSG-PVGPAGAVGPRGPSGPQGIRGDKGEPG---- 1012 Query: 1369 GDLDYNELAVRVSESMQRQGLLQGMA-----YTVQGPPGQPGPQGPPGISKVFSAYSNVT 1423 E R ++ LQG+ + QG PG GP GP G + Sbjct: 1013 ------EKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPA---------- 1056 Query: 1424 ADLMDFFQTYGAIQGPPGQKGEMGTP---------GPKGDRGPAGPPGHPGPPGPRGHKG 1474 GP G+ G G P GP+G +GPAGPPG PGPPGP G G Sbjct: 1057 -----------GPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSG 1105 Query: 1475 EKGDKG--DQVYAGRRRRRSIAVKP 1497 D G Y + R + +++P Sbjct: 1106 GGYDFGYDGDFYRADQPRSAPSLRP 1130 Score = 406 bits (1043), Expect = e-113 Identities = 278/716 (38%), Positives = 315/716 (43%), Gaps = 141/716 (19%) Query: 561 ENGNLRGSPGPKGDMGSPGPKGDRG---FPGTPGIPGPLGH---PGPQGPKGQKGSVGDP 614 E GN+ G PGPKG G PG GD+G G G PGP G+ GP GP+G +G G+ Sbjct: 488 EPGNI-GFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQ 546 Query: 615 GMEGPMGQRGREGPMGPRGEAGPPGS----GEKGERGAAGEPGPHGPPGVPGSVGPKGSS 670 G GP G +G GP GP GE G PG GE G G AG G GPPG G+ GP G Sbjct: 547 GPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPI 606 Query: 671 GSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLP 730 GS GP GPPGP G +G G VG G G GP G PG +G G G +G GEPG+RG Sbjct: 607 GSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEI 666 Query: 731 GAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGL- 789 G G GA+GA G G G G G++G G G GP GP G PG+ G GP GP G Sbjct: 667 GNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFA 726 Query: 790 --PGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPA------ 841 G G+PG KGE GA G +G + V GP GP GA GP GP G PGPA Sbjct: 727 GPAGAAGQPGAKGERGAKG----PKGEN--GVVGPTGPVGAAGPAGPNGPPGPAGSRGDG 780 Query: 842 GPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIP-------GPPGPRGPPGE----GLPGPP 890 GP G+ G GPPGP G GPPGP P GP G +GP G G GPP Sbjct: 781 GPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPP 840 Query: 891 GPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQ 950 G G + E +GPPG PGP G G G G G +GE+GLPG + Sbjct: 841 GFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVA---------GAV 891 Query: 951 GPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSS 1010 G PGP G GP G +G PG G+ G+ P E G GPPG G PG G Sbjct: 892 GEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYP 951 Query: 1011 GQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRT 1070 G I G G PGP GP GP + Sbjct: 952 GN-----IGPV-----------GAAGAPGPHGPVGPAG--------------------KH 975 Query: 1071 SGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAEL 1130 G + S + +GPRGP GP G GD Sbjct: 976 GNRGETGPSGPVGPAG-----------------AVGPRGPSGPQGIRGDK---------- 1008 Query: 1131 SSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRG-------SEFRGIVGPPGPP 1183 G PG GP GLPG L L G G VGP GP Sbjct: 1009 ---------------GEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPR 1053 Query: 1184 GPPGIPGNVWSSISVEDLSSYLHTAGLSFI------PGPPGPPGPPGPRGPPGVSG 1233 GP G G + + + T G + I GP GPPGPPGP GPPGVSG Sbjct: 1054 GPAGPSG----PAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSG 1105 Score = 400 bits (1027), Expect = e-111 Identities = 325/949 (34%), Positives = 380/949 (40%), Gaps = 207/949 (21%) Query: 622 QRGREGPMGPRGEAGPPG----SGEKGERGAAGEPGPHGPPGV----------------P 661 ++G G GPRGE GPPG GE G G G PGP GPPG+ P Sbjct: 31 RKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGP 90 Query: 662 GSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLT 721 G +G G G PG G PGP G QG GE G PG G G GP GP G GE G G Sbjct: 91 GPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKP 150 Query: 722 GEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLT 781 G PG RG+ VG GA+G G G G +G RG GL G+ G G PG G+PG PG Sbjct: 151 GRPGERGV---VGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGEN 207 Query: 782 GPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVP-GPPGPPGAMGPPGPPGAPGP 840 G G G G PG G G PG G + GS P GP GP G+ GPPG PGAPGP Sbjct: 208 GTPGQTGARGLPGERGRVGAPGPAG----ARGSDGSVGPVGPAGPIGSAGPPGFPGAPGP 263 Query: 841 AGPAGLPGHQEVLNLQGPPGPPGPRGPPG-PSIPGPPGPRGPPG---------------- 883 G G G+ GP GP GPRG G P + GP GP G PG Sbjct: 264 KGEIGAVGN------AGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGV 317 Query: 884 ---EGLPGP---PGPPGSFLSNSETFLSGPPGP---------PGPPGPKGDQGPPGPRGH 928 GLPGP PGP G+ + L G PGP G PG G QGPPGP G Sbjct: 318 AGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGE 377 Query: 929 QGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSST 988 +G++G G + S GPPGPPG +G G +G PG G G+ P G+S Sbjct: 378 EGKRGPNGEAGSA---------GPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGP 428 Query: 989 MYVSGP------------PGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQG 1036 V GP GP G PG PG+I +G+E L G+ G Sbjct: 429 AGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGP-------------VGLPGIDG 475 Query: 1037 PPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDV 1096 PGP GP G F + + G+ + D Q Sbjct: 476 RPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPG 535 Query: 1097 RQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGL 1156 Q + Q G +GPPGPPG GLPGP GP G Sbjct: 536 PQGV-QGGKGEQGPPGPPGFQ----------------------------GLPGPSGPAGE 566 Query: 1157 PGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGP 1216 G E L EF G+ GP GP G G PG ++ + S GP Sbjct: 567 VGKPGERGLH----GEF-GLPGPAGPRGERGPPGESGAAGPTGPIGS----------RGP 611 Query: 1217 PGPPGPPGPRGPPGVSGALATYAAENSDSFRSE-----------------LISYLTSPDV 1259 GPPGP G +G PGV GA+ T E L + +P Sbjct: 612 SGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPG- 670 Query: 1260 RSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAG 1319 R G PG G GP G + + + S RG + + G AG Sbjct: 671 RDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAG 730 Query: 1320 SLGAGGAFGEAAGDRGPYGTD--IGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELA 1377 + G GA GE G +GP G + +GP G GAA G NG A GD Sbjct: 731 AAGQPGAKGE-RGAKGPKGENGVVGPTGPVGAAGPAG---PNGPPGPAGSRGD------- 779 Query: 1378 VRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQ 1437 G GM G PG G GPPG S + Sbjct: 780 ----------GGPPGMT----GFPGAAGRTGPPGPSGI------------------SGPP 807 Query: 1438 GPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 GPPG G+ G GP+GD+GP G G G GP G GEKG G+ AG Sbjct: 808 GPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAG 856 Score = 353 bits (905), Expect = 9e-97 Identities = 302/876 (34%), Positives = 359/876 (40%), Gaps = 141/876 (16%) Query: 685 QGLRGEVGLPGVKGDKGPM---GPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGA--- 738 Q L+ E G GD+GP GPPGP G GE GP G G PG G PG G A Sbjct: 23 QSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYD 82 Query: 739 -KG-AMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRP 796 KG +GP GP G GPRG G G PG +G GP+G+PG+PG TGP G +G G PG+ Sbjct: 83 GKGVGLGP-GPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKA 141 Query: 797 GIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQ 856 G G PG PG+ PG G G G G PG PG G G+ GH + L+ Sbjct: 142 GEDGHPGKPGR------------PGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLK 189 Query: 857 GPPGPPGPRGPPGP----SIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSET--------- 902 G PG PG +G PG PG G RG PGE G G PGP G+ S+ Sbjct: 190 GQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPI 249 Query: 903 FLSGPPGPPGPPGPKGD------QGPPGPRGHQGEQGLPGFS--------------TSGS 942 +GPPG PG PGPKG+ GP GP G +GE GLPG S T Sbjct: 250 GSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAK 309 Query: 943 SSFGL-NLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPP 1001 + GL + G PG PGP+G G G G GA G+ P GS G PG GP Sbjct: 310 GAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQ 369 Query: 1002 GPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELA 1061 GPPG G+ +G G GPPGPPG + ++ Sbjct: 370 GPPGPSGEEGKRGP----------------NGEAGSAGPPGPPGLRGSPGSRGLPGADGR 413 Query: 1062 SHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPP------GPPG 1115 + V+ + G +S D + LMGPRG P GP G Sbjct: 414 AGVMGPPGSRG----------ASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAG 463 Query: 1116 ASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSE--- 1172 G L +D G +IG PGP GP G PG + ++ + L G+ Sbjct: 464 KEGPVGLPGIDGRPGPIGPAGARGEPG-NIGFPGPKGPTGDPGKNGDKGHAGLAGARGAP 522 Query: 1173 ----FRGIVGPP------------GPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGP 1216 G GPP GPPGPPG G S ++ GL G Sbjct: 523 GPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGK-PGERGLHGEFGL 581 Query: 1217 PGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPP 1276 PGP GP G RGPPG SG AA + S S PD G G G GP Sbjct: 582 PGPAGPRGERGPPGESG-----AAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPS 636 Query: 1277 GDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGP 1336 G S L + RG + G G++GA G G A GDRG Sbjct: 637 GPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAG-ATGDRGE 695 Query: 1337 YGT--DIGPGGGYGAAAEGGMY--AGNGGLLG-ADFAGDLDYNELAVRVSESMQRQGLLQ 1391 G GP G G+ E G AG G G A AG R ++ + + + Sbjct: 696 AGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAG--QPGAKGERGAKGPKGENGVV 753 Query: 1392 GMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGP 1451 G V G G GP GPPG A S GPPG G G G Sbjct: 754 GPTGPV-GAAGPAGPNGPPG-----PAGSRGDG-------------GPPGMTGFPGAAGR 794 Query: 1452 KGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGR 1487 G GP+G G PGPPGP G +G +G +GDQ GR Sbjct: 795 TGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGR 830 Score = 207 bits (526), Expect = 8e-53 Identities = 206/662 (31%), Positives = 240/662 (36%), Gaps = 187/662 (28%) Query: 839 GPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLS 898 GPAG G G + GPPGPPG G GP+ GPPGP GPP GPPG G+F + Sbjct: 33 GPAGDRGPRGER------GPPGPPGRDGEDGPT--GPPGPPGPP-----GPPGLGGNFAA 79 Query: 899 NSET----FLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPG 954 + GP G GP GP G G PGP+G QG G PG PG Sbjct: 80 QYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPG---------------EPG 124 Query: 955 PPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEI 1014 GP G +G G PG G G P P G + G G PG PG PG G Sbjct: 125 QTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGH-- 182 Query: 1015 QQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYG 1074 +G+ G G PG PG + GE E +G Sbjct: 183 -----------------NGLDGLKGQPGAPG----VKGEPGAPGE-----------NGTP 210 Query: 1075 VSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASG-DGSLLSLDYAELSSR 1133 + + E G G PGP GA G DGS+ + A Sbjct: 211 GQTGARGLPGE-------------------RGRVGAPGPAGARGSDGSVGPVGPAG---- 247 Query: 1134 ILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEF----RGIVGPPGPPGPPGIP 1189 IG GPPG PG PG E G RG VG PG GP G P Sbjct: 248 ----------PIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPP 297 Query: 1190 GNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGP---PGPRGPPGVSGALATYAAENSDSF 1246 GN ++ L+ AGL + G PG PGP PGP G G +GA Sbjct: 298 GNPGAN----GLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGS 353 Query: 1247 RSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSS 1306 + E S G PG GPQGPPG S + S+ RGS Sbjct: 354 KGE-----------SGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSP 402 Query: 1307 YSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGAD 1366 S + G AG +G G+ G + GP G GP G G E G+ G GL G+ Sbjct: 403 GSRGLPGADGRAGVMGPPGSRGAS----GPAGVR-GPNGDAGRPGEPGLM-GPRGLPGSP 456 Query: 1367 FAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADL 1426 G++ GP G+ GP G PGI Sbjct: 457 --GNI---------------------------GPAGKEGPVGLPGID------------- 474 Query: 1427 MDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 G G GP G RG G G PGP GP G G+ GDKG AG Sbjct: 475 -----------------GRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAG 517 Query: 1487 RR 1488 R Sbjct: 518 AR 519 Score = 63.5 bits (153), Expect = 1e-09 Identities = 37/99 (37%), Positives = 44/99 (44%), Gaps = 20/99 (20%) Query: 1399 GPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPA 1458 GPPG PGP GPPG+ F+A + KG PGP G GP Sbjct: 60 GPPGPPGPPGPPGLGGNFAAQYD--------------------GKGVGLGPGPMGLMGPR 99 Query: 1459 GPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 GPPG G PGP+G +G G+ G+ G R A P Sbjct: 100 GPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPP 138 Score = 48.1 bits (113), Expect = 6e-05 Identities = 22/49 (44%), Positives = 27/49 (55%) Query: 1432 TYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKG 1480 T ++Q +KG G GP+G+RGP GPPG G GP G G G G Sbjct: 21 TCQSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPG 69 >gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] Length = 1690 Score = 453 bits (1165), Expect = e-127 Identities = 372/1099 (33%), Positives = 433/1099 (39%), Gaps = 296/1099 (26%) Query: 561 ENGNLRGSPGPKGDMGSPG--------PKGDRGFPGTPGIPGPLGHPG-PQGPKGQKGSV 611 E G++ G PGP G +G PG P G +GFPG PG+PG G PG P G+ G Sbjct: 380 ETGDV-GPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKP 438 Query: 612 GDPGMEGPMGQRG------------REGPMGPRGEAGPPGS-GEKGERGAAG----EPGP 654 G PG+ G G +G GP G +G+ GPPG G KGE+G G EPGP Sbjct: 439 GSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGP 498 Query: 655 HGPPGVPGSVGPKGSSGS------------PGPQGPPGPVGLQGLRGEVGLPG------- 695 GPPG PG G +GS G PGP G GP GL G G G PG Sbjct: 499 MGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGD 558 Query: 696 -----VKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGE-----PGAKGAMGPA 745 VKG KG GP GP G G+ G G G G +G PG G+ PG KG GP Sbjct: 559 MVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPL 618 Query: 746 GPDGHQGP--------------RGEQGLTGMPGIRGPPGPSGDPGK-------------- 777 GP G GP RG G+ G PG+RGP G G G Sbjct: 619 GPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGP 678 Query: 778 PGLTGPQGPQGLPGTPGRPGI------KGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMG- 830 PG GP GP+G PG G PG+ KG PG PG T+E +PGPPG G MG Sbjct: 679 PGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPG---TAE------IPGPPGFRGDMGD 729 Query: 831 -------------PPGPPGAPGPAGPAGLPGHQEVLNLQGPPGP------PGPRGPPG-P 870 PPGPPG+PG G G+PG +L GPPG PG +GP G P Sbjct: 730 PGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHL-GPPGKRGLSGVPGIKGPRGDP 788 Query: 871 SIPGPPGPRGPPG-------------EGLPGPPGPPGSFLSNS------ETFLSGPPGPP 911 PG GP G PG G PG PGPPG + L G PG P Sbjct: 789 GCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSP 848 Query: 912 GPPGPKG---DQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGP------PGPPGPQGPK 962 G PG KG D GPPGP G +G GLPG + + GP PGPPGP+GP+ Sbjct: 849 GAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPR 908 Query: 963 GDKGDPGVPGALGIPSG---PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYIS 1019 G G PG PG G P P G +SG PG G G G+I G E + I Sbjct: 909 GLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAII 968 Query: 1020 EYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFS 1079 +G PG PGPPG GE D YG F Sbjct: 969 SQ-------------KGTPGEPGPPGD-DGFPGERGDKGTPGMQGRRG-EPGRYGPPGFH 1013 Query: 1080 SSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMS 1139 E + GP GPPGPPG++G + ++ Sbjct: 1014 RGEPGE----------------KGQPGPPGPPGPPGSTG---------------LRGFIG 1042 Query: 1140 SSGI--SIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSIS 1197 G+ G PG PGPPG G +G GPPGP G PG PG Sbjct: 1043 FPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHF-GPPGPKGEPGSPG------- 1094 Query: 1198 VEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSP 1257 + +G +PG GP G PG GPPG SG R + + P Sbjct: 1095 ---CPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQP-GEMGDP 1150 Query: 1258 DVRSF-----IVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSV----------- 1301 R I GPPG GP G PG + L +S H Sbjct: 1151 GPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKG 1210 Query: 1302 RRGSSYSSSMSTGG-----------GGAGSLGAGGAFGEAA---------GDRGPYGTDI 1341 RG S +S G G +G G GA G A GD+GP G D Sbjct: 1211 ERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPD- 1269 Query: 1342 GPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPP 1401 GP G G G+ LL + GD + GPP Sbjct: 1270 GPRGAPGPPG----LPGSVDLLRGE-PGDCG------------------------LPGPP 1300 Query: 1402 GQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPP 1461 G PGP GPPG ++ + G GQKG +G PGP+G G GPP Sbjct: 1301 GPPGPPGPPG------------------YKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPP 1342 Query: 1462 GHPGPPGPRGHKGEKGDKG 1480 G G PGP G KG G G Sbjct: 1343 GEKGLPGPPGRKGPTGLPG 1361 Score = 449 bits (1154), Expect = e-125 Identities = 361/1007 (35%), Positives = 423/1007 (42%), Gaps = 229/1007 (22%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPG-----IPGPLGHPGPQGPKGQKGSVGDPGM--EGP 619 G PG G G G G++G PG PG PG G PGP GP G+ G VG PG+ GP Sbjct: 578 GFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGP 637 Query: 620 MGQRGREGPMGPRGEAGPPG-SGEKGER--------------------GAAGEPGPHGPP 658 G+RG G G G GP G G+KG+ G G PGP G P Sbjct: 638 PGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAP 697 Query: 659 GVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKG--PMGPPGPKGDQGEKG 716 G+ GS G KG G+PG PGP G RG++G PG G+KG P+GPPGP G G G Sbjct: 698 GLSGSDGHKGRPGTPGTAEIPGP---PGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNG 754 Query: 717 PRGLTGEP--------------GMRGLPGAVGEPGAKGAMGPAGPDGH---QGPRGEQGL 759 +G+ G+P G+ G+ G G+PG GA GPAG G +GP+G +G Sbjct: 755 QKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGH 814 Query: 760 TGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTV 819 G PG+ GPPG S + G PG+ G G G PG+PG PG KG+PG G + M + Sbjct: 815 AGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGP---PGPAGMKGL 871 Query: 820 PGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPR 879 PG PG PGA GPPG PG PGP G GLPG PPGP GPRG PG PG PG R Sbjct: 872 PGLPGRPGAHGPPGLPGIPGPFGDDGLPG---------PPGPKGPRGLPG--FPGFPGER 920 Query: 880 GPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQG---EQGLP 935 G PG EG PG G PG E +SG PG G G KG GPPG G ++G P Sbjct: 921 GKPGAEGCPGAKGEPG------EKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTP 974 Query: 936 GFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPS--GPSEGGSSSTMYVSG 993 G GPPG G G +GDKG PG+ G G P GP G G Sbjct: 975 GEP------------GPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPP-GFHRGEPGEKG 1021 Query: 994 PPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPG--PVTTIT 1051 PGPPGPPGPPGS G +I L G QG PG PGPPG + Sbjct: 1022 QPGPPGPPGPPGSTGLRG-----FIGF--------PGLPGDQGEPGSPGPPGFSGIDGAR 1068 Query: 1052 GETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPP 1111 G + + ASH +G GP+G P Sbjct: 1069 GPKGNKGDPASH---------FGPP-----------------------------GPKGEP 1090 Query: 1112 GPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGS 1171 G PG G + + L + S G PGPPG G PG + + LRG Sbjct: 1091 GSPGCPGH-------FGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQ 1143 Query: 1172 EF-------RGIVGPPGPPGPPGIPGNVWSS--ISVEDLSSYLHTAGLSFI-----PGPP 1217 RG+ G PG PGPPGI G S + L T G S + PGP Sbjct: 1144 PGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPV 1203 Query: 1218 GPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPG 1277 G PG G RG PG G SP GPPGPPG GPPG Sbjct: 1204 GIPGLKGERGDPGSPGI---------------------SPPGPRGKKGPPGPPGSSGPPG 1242 Query: 1278 DSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPY 1337 + + G + G G G G G+ G+ G Sbjct: 1243 PAG--------ATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDC 1294 Query: 1338 GTDIGPGGGYGAAAEGGMYAGNGGLLGAD-------FAGDLDYNELAVRVSESMQRQGLL 1390 G GP G G G Y G G G D F G + E +GL Sbjct: 1295 GLP-GPPGPPGPPGPPG-YKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGE----KGL- 1347 Query: 1391 QGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPG 1450 GPPG+ GP G PG AD+ D + G + G PG +G G G Sbjct: 1348 -------PGPPGRKGPTGLPGPR----GEPGPPADVDDCPRIPG-LPGAPGMRGPEGAMG 1395 Query: 1451 PKGDRGPAGP--PGHPG---------PPGPRGHKGEKGDKGDQVYAG 1486 G RGP+GP G PG PG G G KGD G+ Y G Sbjct: 1396 LPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPG 1442 Score = 440 bits (1131), Expect = e-123 Identities = 379/1112 (34%), Positives = 442/1112 (39%), Gaps = 318/1112 (28%) Query: 567 GSPGP---KGDMGSPG---PKGDRG-------FPGTPGIPGPLGHPGPQGPKGQ------ 607 G+PGP KG +G PG PKG++G PG G PGP G PG QG KG Sbjct: 463 GNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGW 522 Query: 608 ---KGSVGDPGMEGPMGQRGREGPMGP---------------------RGEAGPPG---- 639 KG G PG EGP G G+ G GP RG GPPG Sbjct: 523 LGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQ 582 Query: 640 ---------SGEKGERGAAGE-----------PGPHGPPGVPGSVGPKGSS--GSPGPQG 677 +GEKG+ G G+ PGP GPPG G VGP G G PG +G Sbjct: 583 PGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERG 642 Query: 678 PPGPVGLQGLRGEVGLPGVKGD-----------KGPM---GPPGPKGDQGEKGPRGLTGE 723 PG G G+RG GL G KGD GP GPPGPKG G +G GL+G Sbjct: 643 HPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGS 702 Query: 724 PGMRGLPGA------VGEPGAKGAMG-----------PAGPD------------------ 748 G +G PG G PG +G MG P GP Sbjct: 703 DGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDP 762 Query: 749 --GHQGPRGEQGLTGMPGIRGP---------PGPSGDPGKPGLTGPQG------------ 785 GH GP G++GL+G+PGI+GP GP+G PG GL GP+G Sbjct: 763 AFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPG 822 Query: 786 ------PQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPG 839 +G PG PG+PG+ G PG+PG G GPPGP G G PG PG PG Sbjct: 823 PPGHSCERGAPGIPGQPGLPGYPGSPG---APGGKGQPGDVGPPGPAGMKGLPGLPGRPG 879 Query: 840 PAGPAGLPGHQEVLNLQGPPGPPGPRGPPG-PSIPGPPGPRGPPG-EGLP---------- 887 GP GLPG G PGPPGP+GP G P PG PG RG PG EG P Sbjct: 880 AHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKG 939 Query: 888 -----------------GPPGPPGSFLSNSETFLSGPPGPPGP---PGPKGDQGPPGPRG 927 GPPG G S+ G PGPPG PG +GD+G PG +G Sbjct: 940 MSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQG 999 Query: 928 HQGEQGL---PGFSTSGSSSFGL-NLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEG 983 +GE G PGF G GPPGPPG G +G G PG+PG G P P Sbjct: 1000 RRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPP 1059 Query: 984 GSSSTMYVSGPP----------GPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSG 1033 G S GP GPPGP G PGS G S L G Sbjct: 1060 GFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGH----------FGASGEQGLPG 1109 Query: 1034 VQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQR 1093 +QGP G PG PGP G + H + LR Q Sbjct: 1110 IQGPRGSPGRPGP----PGSSGPPGCPGDHGMPGLRG---------------------QP 1144 Query: 1094 DDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGI-SIGLPGPPG 1152 ++ + L G G PGPPG G L+ +SG+ +G PGP G Sbjct: 1145 GEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVG 1204 Query: 1153 PPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSS-ISVEDLSSYLHTAGLS 1211 PGL G + + RG GPPGPPG G PG ++ + +D+ Sbjct: 1205 IPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPD-------- 1256 Query: 1212 FIPGPP---GPPGPPGPR---GPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVG 1265 PGPP GPPGP GPR GPPG+ G++ E D + G Sbjct: 1257 --PGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGD----------------CGLPG 1298 Query: 1266 PPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGG 1325 PPGPPGP GPPG D ++G G G G G Sbjct: 1299 PPGPPGPPGPPGYKGFPGCDGKDG------------QKGPVGFPGPQGPHGFPGPPGEKG 1346 Query: 1326 AFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQ 1385 G G +GP G GP G G A+ GL GA +R E Sbjct: 1347 LPG-PPGRKGPTGLP-GPRGEPGPPADVDDCPRIPGLPGAP----------GMRGPEGAM 1394 Query: 1386 RQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGE 1445 L GM +GP G PG +G PG+ +G G G Sbjct: 1395 G---LPGM----RGPSG-PGCKGEPGLD---------------------GRRGVDGVPGS 1425 Query: 1446 MGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKG 1477 G PG KGD G G PG PGPPGP G G KG Sbjct: 1426 PGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKG 1457 Score = 439 bits (1130), Expect = e-123 Identities = 344/980 (35%), Positives = 404/980 (41%), Gaps = 199/980 (20%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGR 625 RG PG GD G GP G GFPG GIPG HPGP GP+G+ G G G G G G Sbjct: 97 RGPPGAAGDKGDKGPTGVPGFPGLDGIPG---HPGPPGPRGKPGMSGHNGSRGDPGFPGG 153 Query: 626 EGPMGPRGEAGPPGSGEKGERG--------AAGEPGPHGPPGVPGSVGPKGSSGSPGPQG 677 G +GP G G P GEKGE+G G G G PG+PG G G+ G GP G Sbjct: 154 RGALGPGGPLGHP--GEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTG 211 Query: 678 PPGPVGLQGLRGEVGLPGVKGD-----KGPMGPPGPKGDQGEKGPRGLT---------GE 723 PG GL G G+ G PG+KG+ KG MG PG G QG GP L GE Sbjct: 212 YPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGE 271 Query: 724 PGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGP 783 G++G+PG VG PG G G +G G +GE+G+ G PG RG PG G PG PGL G Sbjct: 272 KGIKGIPGMVGLPGPPGRKGESG----IGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGE 327 Query: 784 QGPQGLP------GTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGA 837 G G P G G PG +G PG PG +VT L + GPPG PG G G G Sbjct: 328 LGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPP----LPLKGPPGDPGFPGRYGETGD 383 Query: 838 PGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPG--EGLPGPPGPPGS 895 GP GP GL G G GPPGP+G PG +PG PG G PG + PG PG PGS Sbjct: 384 VGPPGPPGLLGRPGEA-CAGMIGPPGPQGFPG--LPGLPGEAGIPGRPDSAPGKPGKPGS 440 Query: 896 FLSNSETFLSGPPGP---------PGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFG 946 L G PG PGP G KG GPPG RG +GE+G G Sbjct: 441 PGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGP-- 498 Query: 947 LNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGS 1006 GPPGPPG G +G KGD G+PG LG P GPPG GPPG PG Sbjct: 499 ---MGPPGPPGLPGRQGSKGDLGLPGWLGTKGDP------------GPPGAEGPPGLPGK 543 Query: 1007 ISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTT-----ITGETFDYSELA 1061 +SG + M ++ + G +GP GPPG PG + GE D Sbjct: 544 HGASGPPGNKGAKGDMVVSRVKGH-KGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPG 602 Query: 1062 SHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGS 1121 H + G+ GP GPPG G G Sbjct: 603 DHEDATPGGKGF-------------------------------PGPLGPPGKAGPVGPPG 631 Query: 1122 LLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPG 1181 L G PGPPG G P G+ G PG Sbjct: 632 L-----------------------GFPGPPGERGHP-----------------GVPGHPG 651 Query: 1182 PPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGA------- 1234 GP G+ G +IS +Y G GPPGP G PGP+G PG+SG+ Sbjct: 652 VRGPDGLKGQKGDTISCN--VTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRP 709 Query: 1235 --LATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGS 1292 T FR ++ + S VGPPGPPG G G + A G Sbjct: 710 GTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGP 769 Query: 1293 SSSSHSSSV-----RRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPG--- 1344 S V RG G G LG G G G G G PG Sbjct: 770 PGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGR-EGHAGFPGVPGPPGHSC 828 Query: 1345 --GGYGAAAEGGM--YAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGP 1400 G G + G+ Y G+ G G G ++ M+ + G Sbjct: 829 ERGAPGIPGQPGLPGYPGSPGAPG----GKGQPGDVGPPGPAGMK----------GLPGL 874 Query: 1401 PGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGP 1460 PG+PG GPPG+ + + + + GPPG KG G PG G G G Sbjct: 875 PGRPGAHGPPGLPGIPGPFGD------------DGLPGPPGPKGPRGLPGFPGFPGERGK 922 Query: 1461 PGHPGPPGPRGHKGEKGDKG 1480 PG G PG +G GEKG G Sbjct: 923 PGAEGCPGAKGEPGEKGMSG 942 Score = 434 bits (1115), Expect = e-121 Identities = 297/770 (38%), Positives = 340/770 (44%), Gaps = 164/770 (21%) Query: 565 LRGSPGPKGDMGSP------------------GPKGDRGFPGTPGIPGPLGHPGPQGPKG 606 L G PG KG G P GPKG G G PG+PGP PG +G Sbjct: 775 LSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGP---PGHSCERG 831 Query: 607 QKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVG 665 G G PG+ G G G G G G+ GPPG +G KG G G PG HGPPG+PG G Sbjct: 832 APGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPG 891 Query: 666 PKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPG 725 P G G PGP GP GP +GL G G PG +G G G PG KG+ GEKG GL G+ G Sbjct: 892 PFGDDGLPGPPGPKGP---RGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRG 948 Query: 726 MRGLPGAVGEPGAKGAM------------GPAGPDGHQGPRGEQGLTGMPGIRGPPGPSG 773 +RG GA+G PG +G M GP G DG G RG++G GM G RG PG G Sbjct: 949 LRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYG 1008 Query: 774 DP----GKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPP--- 826 P G+PG G GP G PG PG G++G G PG + +G PG PGPP Sbjct: 1009 PPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPG-LPGDQGE-----PGSPGPPGFS 1062 Query: 827 ---GAMGPP----------GPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIP 873 GA GP GPPG G G G PGH QG PG GPRG PG P Sbjct: 1063 GIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGR--P 1120 Query: 874 GPPGPRGPPG----EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQ 929 GPPG GPPG G+PG G PG L G PG PGPPG KG G PG G Sbjct: 1121 GPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLH 1180 Query: 930 GEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTM 989 G +G G T G+S GL+ GPPGP G G KG++GDPG PG P GP Sbjct: 1181 GLKGQKG--TKGAS--GLHDVGPPGPVGIPGLKGERGDPGSPGI--SPPGPRG------- 1227 Query: 990 YVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTT 1049 GPPGPPG GPPG ++G+ + D G +G PGPPG PG V Sbjct: 1228 -KKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDL 1286 Query: 1050 ITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRG 1109 + GE D L GP G Sbjct: 1287 LRGEPGDCG---------------------------------------------LPGPPG 1301 Query: 1110 PPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLR 1169 PPGPPG G D + G +G PGP GP G PG E Sbjct: 1302 PPGPPGPPGYKGFPGCDGKD---------GQKG-PVGFPGPQGPHGFPGPPGE------- 1344 Query: 1170 GSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPP 1229 +G+ GPPG GP G+PG D+ GL PG PG GP G G P Sbjct: 1345 ----KGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGL---PGAPGMRGPEGAMGLP 1397 Query: 1230 GVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDS 1279 G+ G + + E D R + G PG PGP G GD+ Sbjct: 1398 GMRG-------PSGPGCKGE-----PGLDGRRGVDGVPGSPGPPGRKGDT 1435 Score = 424 bits (1090), Expect = e-118 Identities = 346/995 (34%), Positives = 411/995 (41%), Gaps = 219/995 (22%) Query: 565 LRGSPGPKGD--MGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQ 622 L G PG KG+ +G+ G KG GFPG G PG G PG G KG+ G VGDPG+ G +G Sbjct: 283 LPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGP 342 Query: 623 RGREGPMGPRGEAGPPG------------SGEKGERGAAGEPGPHGPPGVPGSVGPKGSS 670 +G G RG GPPG G+ G G GE G GPPG PG +G G + Sbjct: 343 KGDPGN---RGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEA 399 Query: 671 --GSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRG 728 G GP GP G GL GL GE G+PG P G G+ G GL G PG++G Sbjct: 400 CAGMIGPPGPQGFPGLPGLPGEAGIPG--------RPDSAPGKPGKPGSPGLPGAPGLQG 451 Query: 729 LPGA------VGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTG 782 LPG+ VG PG +G G GP G +GP+GE+G G+ PGP G PG PGL G Sbjct: 452 LPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACE--PGPMGPPGPPGLPG 509 Query: 783 PQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAG 842 QG +G G PG G KG+PG PG +EG PG PG GA GPPG GA G Sbjct: 510 RQGSKGDLGLPGWLGTKGDPGPPG----AEGP-----PGLPGKHGASGPPGNKGAKGDMV 560 Query: 843 PAGLPGHQEVLNLQGPPGPPGPRGPPG-------PSIPGPPGPRG---PPGEGLPGPPGP 892 + + GH+ GPPG PG G G PGPPG P G+G PGP GP Sbjct: 561 VSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGP 620 Query: 893 PGSFLSNSETFLSGPPGPPGP--PGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNL- 949 PG +GP GPPG PGP G++G PG GH G +G G + N+ Sbjct: 621 PGK---------AGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVT 671 Query: 950 ----QGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPG 1005 GPPG GP GPKG G G PG G G+ T + GPPG G G PG Sbjct: 672 YPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPG 731 Query: 1006 SISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVV 1065 G S GPPGPPG PG + G+ + A Sbjct: 732 FGGEKG--------------------SSPVGPPGPPGSPG----VNGQKGIPGDPA---F 764 Query: 1066 SYLRTSGY-GVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLS 1124 +L G G+S + GPRG PG PGA G + Sbjct: 765 GHLGPPGKRGLSGVPG-----------------------IKGPRGDPGCPGAEGPAGIPG 801 Query: 1125 LDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPG 1184 L G G G PG PG PG S E RG+ GI G PG PG Sbjct: 802 F---------LGLKGPKGRE-GHAGFPGVPGPPGHSCE------RGAP--GIPGQPGLPG 843 Query: 1185 PPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSD 1244 PG PG D+ AG+ +PG PG PG GP G PG+ G Sbjct: 844 YPGSPGAPGGKGQPGDVGPP-GPAGMKGLPGLPGRPGAHGPPGLPGIPG----------- 891 Query: 1245 SFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRG 1304 P + GPPGP GP+G PG + +G Sbjct: 892 ------------PFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKG 939 Query: 1305 SSYSSSMSTGGGGAGSLGAGGAFGEAA--------GDRGPYGTDIGPG--------GGYG 1348 S G G++G G GE A G+ GP G D PG G G Sbjct: 940 MSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQG 999 Query: 1349 AAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQG 1408 E G Y G G G+ +G PG PGP G Sbjct: 1000 RRGEPGRYGPPGFHRGEP--GE---------------------------KGQPGPPGPPG 1030 Query: 1409 PPGISKV--FSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRG-PA---GPPG 1462 PPG + + F + + D Q GPPG G G GPKG++G PA GPPG Sbjct: 1031 PPGSTGLRGFIGFPGLPGD-----QGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPG 1085 Query: 1463 HPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 G PG G G G G+Q G + R +P Sbjct: 1086 PKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRP 1120 Score = 418 bits (1074), Expect = e-116 Identities = 297/764 (38%), Positives = 345/764 (45%), Gaps = 142/764 (18%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPG---PQGPKGQKGSVGDPGMEGPMGQR 623 G PG +G G PG KG RG PG PG GP G PG +GPKG++G G PG+ GP G Sbjct: 768 GPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHS 827 Query: 624 ---------------------GREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVP 661 G G G G+ GPPG +G KG G G PG HGPPG+P Sbjct: 828 CERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLP 887 Query: 662 GSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLT 721 G GP G G PGP GP GP GL G G PG +G G G PG KG+ GEKG GL Sbjct: 888 GIPGPFGDDGLPGPPGPKGPRGLPGFPG---FPGERGKPGAEGCPGAKGEPGEKGMSGLP 944 Query: 722 GEPGMRGLPGAVGEPGAKGAM------------GPAGPDGHQGPRGEQGLTGMPGIRGPP 769 G+ G+RG GA+G PG +G M GP G DG G RG++G GM G RG P Sbjct: 945 GDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEP 1004 Query: 770 GPSGDPG----KPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGP 825 G G PG +PG G GP G PG PG G++G G PG + +G PG PGP Sbjct: 1005 GRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPG-LPGDQGE-----PGSPGP 1058 Query: 826 PG------AMGPPG----------PPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG 869 PG A GP G PPG G G G PGH QG PG GPRG PG Sbjct: 1059 PGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPG 1118 Query: 870 PSIPGPPGPRGPPG----EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGP 925 PGPPG GPPG G+PG G PG L G PG PGPPG KG G PG Sbjct: 1119 R--PGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGL 1176 Query: 926 RGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPG-----------------PQGPKGDKGDP 968 G G +G G T G+S GL+ GPPGP G P GP+G KG P Sbjct: 1177 NGLHGLKGQKG--TKGAS--GLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPP 1232 Query: 969 GVPGALGIPSGPS--EGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDS 1026 G PG+ G P GP+ G + + GPPG GPPGP G + G + ++ + Sbjct: 1233 GPPGSSG-PPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEP 1291 Query: 1027 IRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSED 1086 G+ GPPGPPGPPGP D + V + G F + Sbjct: 1292 GDC---GLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGF--PGPQGPHGFPGPPGEKG 1346 Query: 1087 ILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGI--- 1143 + R L GPRG PGPP D RI + G+ Sbjct: 1347 LPGPPGRKGPTG-----LPGPRGEPGPPADVDD-----------CPRIPGLPGAPGMRGP 1390 Query: 1144 --SIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDL 1201 ++GLPG GP G PG E L RG+ G PG PGPPG G+ Sbjct: 1391 EGAMGLPGMRGPSG-PGCKGEPGL-----DGRRGVDGVPGSPGPPGRKGDTGED------ 1438 Query: 1202 SSYLHTAGLSFIPGPPGPPGPPGPRG-PPGVSGALATYAAENSD 1244 G PGPPGP G PGP+G PG G +D Sbjct: 1439 -------GYPGGPGPPGPIGDPGPKGFGPGYLGGFLLVLHSQTD 1475 Score = 408 bits (1049), Expect = e-113 Identities = 325/886 (36%), Positives = 367/886 (41%), Gaps = 150/886 (16%) Query: 559 EQENGNLRGSPGPKGDMGSPGPKGD-----------RGFPGTPGIPGPLGHPGPQGPKGQ 607 E+ + + G PG +G G G KGD G PG G PGP G PGPQG G Sbjct: 640 ERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGL 699 Query: 608 KGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAA--GEPGPHGPPGVPGS-- 663 GS G G G G GP G RG+ G PG G GE+G++ G PGP G PGV G Sbjct: 700 SGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFG--GEKGSSPVGPPGPPGSPGVNGQKG 757 Query: 664 ------------VGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPM-------- 703 G +G SG PG +GP G G G G G+PG G KGP Sbjct: 758 IPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGF 817 Query: 704 -GPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGM 762 G PGP G E+G G+ G+PG+ G PG+ G PG KG G GP G G +G GL G Sbjct: 818 PGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGR 877 Query: 763 PGIRGP------PGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGA---PGKIVTSEG 813 PG GP PGP GD G PG GP+GP+GLPG PG PG +G+PGA PG Sbjct: 878 PGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGE 937 Query: 814 SSMLTVPGP---PGPPGAMGPP------------GPPGAPGPAGPAGLPGH---QEVLNL 855 M +PG G GA+GPP G PG PGP G G PG + + Sbjct: 938 KGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGM 997 Query: 856 QGPPGPPGPRGPPG--------PSIPGPPGPRGPPGE-------GLPGPPGPPGSFLSNS 900 QG G PG GPPG PGPPGP GPPG G PG PG G S Sbjct: 998 QGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPG 1057 Query: 901 ETFLSGPPGPPGPPGPKGDQ----GPPGPRGHQGEQGLPG-FSTSGSSSFGLNLQGPPGP 955 SG G GP G KGD GPPGP+G G G PG F SG +QGP G Sbjct: 1058 PPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLP-GIQGPRGS 1116 Query: 956 PGPQGPKGDKGDPGVPGALGIP---SGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQ 1012 PG GP G G PG PG G+P P E G + G PG PGPPG G S G Sbjct: 1117 PGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGL 1176 Query: 1013 EIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSG 1072 + + + S L V GPPGP G PG + GE D G Sbjct: 1177 NGLHGL-KGQKGTKGASGLHDV-GPPGPVGIPG----LKGERGDPGSPGISPPGPRGKKG 1230 Query: 1073 YGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSS 1132 SS D+ GP GP GP GA G L Sbjct: 1231 PPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGL---------P 1281 Query: 1133 RILSYMSSSGISIGLPGPPGPPGLPG-TSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGN 1191 + + GLPGPPGPPG PG Y+ +G VG PGP GP G PG Sbjct: 1282 GSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPG- 1340 Query: 1192 VWSSISVEDLSSYLHTAGLSFIPGPPGPPGP---PGPRGPPGVSGALATYAAENSDSFRS 1248 G +PGPPG GP PGPRG PG A+ D R Sbjct: 1341 ---------------PPGEKGLPGPPGRKGPTGLPGPRGEPGP-------PADVDDCPR- 1377 Query: 1249 ELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYS 1308 I G PG PG +GP G L G RRG Sbjct: 1378 --------------IPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDG-RRGVDGV 1422 Query: 1309 SSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGG 1354 G G G G G G GP G D GP G+G GG Sbjct: 1423 PGSPGPPGRKGDTGEDGYPG-GPGPPGPIG-DPGP-KGFGPGYLGG 1465 Score = 360 bits (925), Expect = 4e-99 Identities = 311/951 (32%), Positives = 384/951 (40%), Gaps = 206/951 (21%) Query: 636 GPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPG 695 GP G + E G GPPG PG GP G G+PGP G G G++G RG G G Sbjct: 45 GPCGGRDCSVCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAG 104 Query: 696 VKGDKGPMGPPG---PKGDQGEKGPRGLTGEPGMRGLPGAVGEPG---AKGAMGPAGPDG 749 KGDKGP G PG G G GP G G+PGM G G+ G+PG +GA+GP GP G Sbjct: 105 DKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLG 164 Query: 750 H--------------------QGPRGEQGLTGMPG---IRGPPGPSGDPGKPGLTGPQGP 786 H QG RG+ GL G+PG GP GP+G PG+PGL GP G Sbjct: 165 HPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQ 224 Query: 787 QGLPGTPGRPGI--KGEPGAPGKIVT--SEGSSMLTVP----------GPPGPPGAMGPP 832 G PG G PG+ KG+ G PG++ S G ++L P G G PG +G P Sbjct: 225 PGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLP 284 Query: 833 GPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG-------------PSIPGPPGPR 879 GPPG G +G G G + + GP G PG G PG P + G GP+ Sbjct: 285 GPPGRKGESG-IGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPK 343 Query: 880 GPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFST 939 G PG G PGPPG L L GPPG PG PG G+ G GP G G G PG + Sbjct: 344 GDPGNR--GHPGPPG-VLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEAC 400 Query: 940 SGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPG 999 +G GPPGPQG G PG+PG GIP P G PG PG Sbjct: 401 AGMI----------GPPGPQG---FPGLPGLPGEAGIPGRPDSA--------PGKPGKPG 439 Query: 1000 PPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSE 1059 PG PG+ G I + + + G++G GPPG GP GE Sbjct: 440 SPGLPGAPGLQGLPGSSVIYCSVGNPGPQ----GIKGKVGPPGGRGP----KGEK----- 486 Query: 1060 LASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGD 1119 +E + A MGP GPPG PG G Sbjct: 487 -----------------------GNEGLCACEPGP----------MGPPGPPGLPGRQGS 513 Query: 1120 GSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPG------------TSYEELLSL 1167 L L ++ + G G PG GPPGLPG + ++S Sbjct: 514 KGDLGLP---------GWLGTKG-DPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSR 563 Query: 1168 LRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSS-------YLHTAGLSFIPGPPGPP 1220 ++G +G GP GPPG PG PG+ + T G PGP GPP Sbjct: 564 VKGH--KGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPP 621 Query: 1221 G--------------PPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGP 1266 G PPG RG PGV G + + + IS + R G Sbjct: 622 GKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGF 681 Query: 1267 PGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGA 1326 GPPGP+G PG S S H R G+ ++ + G G +G G Sbjct: 682 DGPPGPKGFPGPQGAPGL-------SGSDGHKG--RPGTPGTAEIPGPPGFRGDMGDPGF 732 Query: 1327 FGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQR 1386 GE P G GP G G + G+ GD + L + Sbjct: 733 GGEKGSS--PVGPP-GPPGSPGVNGQKGI------------PGDPAFGHLGPPGKRGLSG 777 Query: 1387 QGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEM 1446 ++G +G PG PG +GP GI + F + GPPG E Sbjct: 778 VPGIKGP----RGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFP---GVPGPPGHSCER 830 Query: 1447 GTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 G PG G G PG+PG PG G KG+ GD G AG + + +P Sbjct: 831 GAPGIPGQ---PGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRP 878 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 453 bits (1165), Expect = e-127 Identities = 385/1131 (34%), Positives = 454/1131 (40%), Gaps = 264/1131 (23%) Query: 560 QENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPL--------GHPGPQGPKGQKG-- 609 QE G+ G+PGP G G+ GP+G G PG PG PG G PG +G KG++G Sbjct: 351 QEKGD-EGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRP 409 Query: 610 ------SVGDPGMEGPMGQRGREGPMGPRGEA----GPPGS----------GEKGERGAA 649 + G PG G G G GP GP G+ GPPG G G G Sbjct: 410 GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPK 469 Query: 650 GEPG------PH--GPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKG 701 GEPG P+ GPPG+PG G G G PG QG G G G G GLPG G G Sbjct: 470 GEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPG 529 Query: 702 PMGPPGPKGDQGEK----------GPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQ 751 G PG KG++GE G GL G+PG +GL G G PG KG GP G Sbjct: 530 AQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALS 589 Query: 752 GPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTS 811 G +G+QG G PG G PGP+G G PG GPQG GL GT G PG G PG G Sbjct: 590 GEKGDQGPPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVPGAPGPPGEAGP--RG 646 Query: 812 EGSSMLTVPGPPGPPGAMGPPGP--------------------------------PGAPG 839 E S VPGPPGPPG G PGP PG PG Sbjct: 647 ELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPG 706 Query: 840 PAGPAGLPGHQEVLN---------LQGPPGPPGPRGPPGPSIPGPPGPRGPPGE------ 884 P G G PG + L L G PG PG +G P ++PG PG G PGE Sbjct: 707 PKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGE 766 Query: 885 ----GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPG-----PRGHQG----- 930 GLPG PG PG+ L GP G PG PGP G+QGPPG PRG QG Sbjct: 767 HGEIGLPGLPGLPGT---PGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLN 823 Query: 931 ----------------EQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGAL 974 + G+PG SG G PG G GP G +G PG PG L Sbjct: 824 GLKGQQGRRGKTGPKGDPGIPGLDRSGFPG-ETGSPGIPGHQGEMGPLGQRGYPGNPGIL 882 Query: 975 GIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSG----------------------- 1011 G P G GPPGPPG PG PG S G Sbjct: 883 GPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNP 942 Query: 1012 --QEIQQYISEYMQSDSIRSY-----------------LSGVQGPPGPPGPPGPVTTITG 1052 EI I + + ++ + L G++G PGP GPPGP + G Sbjct: 943 GPSEISHVIGDKGEP-GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL-G 1000 Query: 1053 ETFDYSELASH-VVSYLRTSGY-------GVSLFSSSISSEDILAV--LQRDDVRQ-YLR 1101 T + E + + G G F + + LQ D Y Sbjct: 1001 STGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSE 1060 Query: 1102 QYLMGPRGPPGPPGASGDGSLLSLDYAELSSR-ILSYMSSSGISIGLPGPPGPPGLPGTS 1160 GP GP G PG GD E+ ++ +G G PG PG PGLPG Sbjct: 1061 GTRPGPPGPTGDPGLPGDMG----KKGEMGQPGPPGHLGPAGPE-GAPGSPGSPGLPGKP 1115 Query: 1161 YEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPP 1220 +G +G++GPPG GPPG+PG S + G IPGP G Sbjct: 1116 GPHGDLGFKG--IKGLLGPPGIRGPPGLPGFPGSPGPM----GIRGDQGRDGIPGPAGEK 1169 Query: 1221 G-------PPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQ 1273 G PPGPRG PG GA A R +G GP GP Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPG-----------RKGAMGDAGPRGPT 1218 Query: 1274 G------PPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAF 1327 G PPG + + +RG S RGS + G G+ +G G Sbjct: 1219 GIEGFPGPPGLPGAIIPGQTGNRGPPGS-------RGSPGAPG-PPGPPGSHVIGIKGDK 1270 Query: 1328 GEAA--GDRGPYGT--DIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSES 1383 G G +GP GT D+GP G GA G+ G F G V Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG----------VKGE 1320 Query: 1384 MQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYG--AIQGPPG 1441 G L + GPPG GP+GPPG+ T ++ + G G PG Sbjct: 1321 KGNPGFLGSI-----GPPGPIGPKGPPGVRG-----DPGTLKIISLPGSPGPPGTPGEPG 1370 Query: 1442 QKGEMGTPGPKGDRGPAGP------PGHPGPPGPRGHKGEKGDKGDQVYAG 1486 +GE G PGP G+ GP GP G PG PGP G KG KG KG+ AG Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAG 1421 Score = 449 bits (1156), Expect = e-126 Identities = 354/1008 (35%), Positives = 421/1008 (41%), Gaps = 185/1008 (18%) Query: 563 GNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHP---GPQGPKGQKGSVGDPGME-- 617 G+ +G+PG G G PG G GFPG+ G+ G G P G G KGQKG +G PG Sbjct: 284 GSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGP 343 Query: 618 -------------------GPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPG----- 653 GP G RG +GP GP G G PGS G RGA G PG Sbjct: 344 TEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSK 403 Query: 654 ---------PHGPPGVPGSVGPKGSSGSPGPQGPP-------GPVGLQGLRGEVGLPGVK 697 G PG PG G G GSPGP GPP GP G GL G +G PG+ Sbjct: 404 GERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIP 463 Query: 698 GDKGPMGPPGPKGDQ-----GEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQG 752 G GP G PG Q G G GL G G++G+PG G G KG+ G G G G Sbjct: 464 GVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPG 523 Query: 753 PRGEQGLTGMPGIRG-------PPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAP 805 G G G PG++G P G G PG PGL G G +GL G PG PG+KG PG Sbjct: 524 FPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPK 583 Query: 806 GKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPR 865 G++ S PG PG PG+ GP GP G PG GP G PG Q + G PGPPG Sbjct: 584 GELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGTQGVPGAPGPPGEA 642 Query: 866 GPPG-----PSIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGD 919 GP G +PGPPGP GPPG G GPPG PGS + L GP G PG PG G Sbjct: 643 GPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG-IGF 701 Query: 920 QGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGV--PGALGIP 977 GPPGP+ G+QG PG T GS G PG PG G G KG+P V PG G P Sbjct: 702 PGPPGPK---GDQGFPG--TKGSLGCP-GKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTP 755 Query: 978 SGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGP 1037 P E G+S G PG PG PG PG+ G G G Sbjct: 756 GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR-------------------GDPGQ 796 Query: 1038 PGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVR 1097 PGPPG GP G + A + G Sbjct: 797 PGPPGEQGP----PGRCIEGPRGAQGLPGLNGLKG------------------------- 827 Query: 1098 QYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLP 1157 Q R+ GP+G PG PG G S I + G +G G PG PG+ Sbjct: 828 QQGRRGKTGPKGDPGIPGLDRSG----FPGETGSPGIPGHQGEMG-PLGQRGYPGNPGIL 882 Query: 1158 GTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPP 1217 G E+ + + G F G +GPPGPPG PG PG S + + T G G Sbjct: 883 GPPGEDGVIGMMG--FPGAIGPPGPPGNPGTPGQ-RGSPGIPGVKGQRGTPGAKGEQGDK 939 Query: 1218 GPPGPP------GPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPG 1271 G PGP G +G PG+ G + + P ++ + G PGP G Sbjct: 940 GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG-------MPGLKG-LKGLPGPAG 991 Query: 1272 PQGPPGDSRLLSTDASHSRGSSSSSHSSSVR--RGSSYSSSMSTGGGGAGSLGAGGAFGE 1329 P GP GD GS+ + +R GS + M G G+LG G G Sbjct: 992 PPGPRGD-----------LGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR 1040 Query: 1330 AA--GDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQ 1387 G G G PG G G+ GL GD+ M + Sbjct: 1041 PGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL-----PGDMG-------KKGEMGQP 1088 Query: 1388 GLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMG 1447 G + GP G PG G PG+ + ++ + I+GPPG G G Sbjct: 1089 GPPGHLG--PAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPG 1146 Query: 1448 TPGPKGDRGPAGPPGHPG-------------PPGPRGHKGEKGDKGDQ 1482 +PGP G RG G G PG PPGPRG+ G +G KGD+ Sbjct: 1147 SPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDR 1194 Score = 442 bits (1137), Expect = e-123 Identities = 357/1038 (34%), Positives = 431/1038 (41%), Gaps = 205/1038 (19%) Query: 572 KGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQR--GREGPM 629 KGD G PG G +G PG PG PGP+G PGP G G G++G G +G MG+R G +G Sbjct: 170 KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGER 229 Query: 630 GPRGEAGPPG------------------SGEKGERGAAGEPGPHGPPGVPGSV--GPKGS 669 G +G GPPG GEKG++GA GEPGP GP G+PG KG+ Sbjct: 230 GVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGA 289 Query: 670 SGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTG------- 722 G PG QG PG G+ G G G+ G +G G MG G KG +G+ GP G G Sbjct: 290 PGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDT 349 Query: 723 --EPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGE-----QGLTGMPGIRGPPGPSGDP 775 E G G PG G GA+G GP+GP G G G +G G PG++G G G P Sbjct: 350 YQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRP 409 Query: 776 GKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGS-------------SMLTVPGP 822 GK + P P G G+PG PG G PG PG IV +G + V GP Sbjct: 410 GKDAMGTPGSP-GCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGP 468 Query: 823 PGPPGAM--------GPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG----- 869 G PG + GPPG PG PG G G+PG Q L+G PG PG G PG Sbjct: 469 KGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFP 528 Query: 870 ---------------------PSIPGPPGPRGPPG----EGLPGPPG------PPGSFLS 898 +PG PG RG PG +G+PG PG P G Sbjct: 529 GAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELAL 588 Query: 899 NSETFLSGPPGPPGPPGPKGDQGPPGPRGH--------QGEQGLPGF-------STSGSS 943 + E GPPG PG PG G GP GP G+ QG QG+PG G Sbjct: 589 SGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGEL 648 Query: 944 SFGLNLQGPPGPPGPQGPKGDKGDPGVPGALG------IPSGPSEGGSSSTMYVSGPPGP 997 S + GPPGPPGP G G +G PG+PG+LG +P E G + GPPGP Sbjct: 649 SVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF-PGPPGP 707 Query: 998 PGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDY 1057 G G PG+ S G G G PG PG PG + G Sbjct: 708 KGDQGFPGTKGSLG-------------------CPGKMGEPGLPGKPG----LPGAK--- 741 Query: 1058 SELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGAS 1117 E A + T G+ +S E L L + L GPRG PG PG Sbjct: 742 GEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPG-NEGLDGPRGDPGQPGPP 800 Query: 1118 GDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIV 1177 G+ G I GP G GLPG L+ L+G + G Sbjct: 801 GE------------------QGPPGRCI--EGPRGAQGLPG------LNGLKGQQ--GRR 832 Query: 1178 GPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALAT 1237 G GP G PGIPG D S + G IPG G GP G RG PG G L Sbjct: 833 GKTGPKGDPGIPG--------LDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884 Query: 1238 YAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSH 1297 + +I + P +GPPGPPG G PG + + + Sbjct: 885 PGEDG-------VIGMMGFPGA----IGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAK 933 Query: 1298 SSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPG--GGYGAAAEGGM 1355 +G+ S +S G G G G F G++G G PG G G G Sbjct: 934 GEQGDKGNPGPSEISHVIGDKGEPGLKG-FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992 Query: 1356 YAGNGGLLGADFAGDLDYNELAVRVSESMQRQGL--LQGMAYTVQGPPGQPGPQGPPGI- 1412 G L G+ + SM G+ +G T+ G PG+ G G PGI Sbjct: 993 PGPRGDLGSTGNPGEPGLR----GIPGSMGNMGMPGSKGKRGTL-GFPGRAGRPGLPGIH 1047 Query: 1413 ----SKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPG 1468 K YS T + G G+KGEMG PGP G GPAGP G PG PG Sbjct: 1048 GLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPG 1107 Query: 1469 PRGHKGEKGDKGDQVYAG 1486 G G+ G GD + G Sbjct: 1108 SPGLPGKPGPHGDLGFKG 1125 Score = 419 bits (1076), Expect = e-116 Identities = 349/1025 (34%), Positives = 410/1025 (40%), Gaps = 238/1025 (23%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGH------PGPQGPKGQKGSVGDPGMEGP 619 +G G KG G PG G +GF G G+PGP G PG G KG +G G PG G Sbjct: 45 KGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGS 104 Query: 620 MGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSP----- 673 G G G GP G G PG SG KGE+G G PG G PG+PG+ G KG G+P Sbjct: 105 PGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164 Query: 674 ---------------GPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGE---- 714 GPQG PGP G G G G PG G G MGP GPKG GE Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIG 224 Query: 715 -KGPRGLTGEPGMRGLPGAV--------------GEPGAKGAMGPAGPDGHQGPRGE--- 756 KG RG+ G G G PG V GE G KGAMG GP G G GE Sbjct: 225 HKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYG 284 Query: 757 --QGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGS 814 +G G PG++G PG G PG PG G +G +G PG G GIKG+ G G + Sbjct: 285 SEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPT 344 Query: 815 SMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGP--PGPRGPPG-PS 871 G G GPPGP GA GP GP+G PG + G PG PG RG PG P Sbjct: 345 EYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPG------VPGSPGSSRPGLRGAPGWPG 398 Query: 872 IPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGD----QGPPGPRG 927 + G G RG PG+ G PG PG S G PG PGPPGP GD +GPPG G Sbjct: 399 LKGSKGERGRPGKDAMGTPGSPGCAGS------PGLPGSPGPPGPPGDIVFRKGPPGDHG 452 Query: 928 ---HQGEQGLPGFSTSGSSSFGLNLQ-----GPPGPPGPQGPKGDKGDPGVPGALGIPSG 979 + G G+PG L Q GPPG PG G G KG PG GA G+ Sbjct: 453 LPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGS 512 Query: 980 PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSI------RSYLSG 1033 P G++ + G PG PG G PG G+ +Q + D R L G Sbjct: 513 PGSPGNTG---LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDG 569 Query: 1034 VQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQR 1093 + G PG G PGP ELA +S E Sbjct: 570 IPGTPGVKGLPGPK----------GELA--------------------LSGEK------- 592 Query: 1094 DDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGP 1153 G +GPPG PG+ G PGP GP Sbjct: 593 ------------GDQGPPGDPGSPGS----------------------------PGPAGP 612 Query: 1154 PGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFI 1213 G PG + L +G++ G+ G PGPPG G G + S V Sbjct: 613 AGPPGYGPQGEPGL-QGTQ--GVPGAPGPPGEAGPRGELSVSTPVPGP------------ 657 Query: 1214 PGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVG-----PPG 1268 PGPPGPPG PGP+GPPG+ G+L L PD I G PPG Sbjct: 658 PGPPGPPGHPGPQGPPGIPGSLGKCGDPG-----------LPGPDGEPGIPGIGFPGPPG 706 Query: 1269 PPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFG 1328 P G QG PG L +G + +M G G G G G G Sbjct: 707 PKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEP-AVAMPGGPGTPGFPGERGNSG 765 Query: 1329 EAA-----------GDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELA 1377 E G G G D GP G G G G + Sbjct: 766 EHGEIGLPGLPGLPGTPGNEGLD-GPRGDPGQPGPPGEQGPPGRCIEGP----------- 813 Query: 1378 VRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVF-SAYSNVTADL---------- 1426 R ++ + L+G QG G+ GP+G PGI + S + T Sbjct: 814 -RGAQGLPGLNGLKGQ----QGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMG 868 Query: 1427 ---MDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQV 1483 + I GPPG+ G +G G G GP GPPG+PG PG RG G G KG + Sbjct: 869 PLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRG 928 Query: 1484 YAGRR 1488 G + Sbjct: 929 TPGAK 933 Score = 418 bits (1075), Expect = e-116 Identities = 349/1036 (33%), Positives = 415/1036 (40%), Gaps = 262/1036 (25%) Query: 560 QENGNLRGSPG----PKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQG---PKGQKGSVG 612 Q + L+G G P+G +G PG G RG PG G+ G G PG +G PKG+ G Sbjct: 531 QGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSG 590 Query: 613 DPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGE---RGAAGEPGPHGPPG---------- 659 + G +GP G G G GP G AGPPG G +GE +G G PG GPPG Sbjct: 591 EKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV 650 Query: 660 ---VPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGP-----MGPPGPKGD 711 VPG GP G G PGPQGPPG G G G+ GLPG G+ G GPPGPKGD Sbjct: 651 STPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGD 710 Query: 712 QGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMG------PAGPD--------GHQGPRGEQ 757 QG G +G G PG G PG G+PG GA G P GP G+ G GE Sbjct: 711 QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770 Query: 758 GLTGMPGIRGPP------GPSGDPGKPG-----------LTGPQGPQGLP---------G 791 GL G+PG+ G P GP GDPG+PG + GP+G QGLP G Sbjct: 771 GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830 Query: 792 TPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQE 851 G+ G KG+PG PG + S PG PG G MGP G G PG G G PG Sbjct: 831 RRGKTGPKGDPGIPG-LDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889 Query: 852 VLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGP- 910 V+ + G PG GP GPPG PG PG RG P G+PG G G+ + E G PGP Sbjct: 890 VIGMMGFPGAIGPPGPPGN--PGTPGQRGSP--GIPGVKGQRGTPGAKGEQGDKGNPGPS 945 Query: 911 --------PGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGL-NLQGPPGPPGPQGP 961 G PG KG G PG +G++G G+PG GL L GP GPPGP+G Sbjct: 946 EISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLK-------GLKGLPGPAGPPGPRGD 998 Query: 962 KGDKGDPGVPGALGIPSG------PSEGGSSSTMYV------------------------ 991 G G+PG PG GIP P G T+ Sbjct: 999 LGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGY 1058 Query: 992 -----SGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGP 1046 GPPGP G PG PG + G+ Q ++ +G +G PG PG PG Sbjct: 1059 SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGP-------AGPEGAPGSPGSPG- 1110 Query: 1047 VTTITGETFDYSELA-SHVVSYLRTSGY----GVSLFSSSISSEDILAVLQRDDV----- 1096 + G+ + +L + L G G+ F S I RD + Sbjct: 1111 ---LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAG 1167 Query: 1097 ---RQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGP 1153 L + GPRG PG GA GD + G G+ G PGP Sbjct: 1168 EKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRG-PTGIEGFPGP 1226 Query: 1154 PGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPP-----GIPGNVWSSISVEDLSSYLHTA 1208 PGLPG RG G PGPPGPP GI G+ S+ TA Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK-GSMGHPGPKGPPGTA 1285 Query: 1209 GLSFIP---GPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVG 1265 G P G PG PG PGPRG PG G + + F +G Sbjct: 1286 GDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS--------------IG 1331 Query: 1266 PPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGG 1325 PPGP GP+GPPG RG G+ S+ G G+ G G Sbjct: 1332 PPGPIGPKGPPG-----------VRGDP----------GTLKIISLPGSPGPPGTPGEPG 1370 Query: 1326 AFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQ 1385 GE G GP G ++GP G G + Sbjct: 1371 MQGE-PGPPGPPG-NLGPCGPRGKPGK--------------------------------- 1395 Query: 1386 RQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGE 1445 G PG PGP G G +G PG G Sbjct: 1396 ------------DGKPGTPGPAGEKGNK---------------------GSKGEPGPAGS 1422 Query: 1446 MGTPGPKGDRGPAGPP 1461 G PG KG RG +G P Sbjct: 1423 DGLPGLKGKRGDSGSP 1438 Score = 410 bits (1055), Expect = e-114 Identities = 302/869 (34%), Positives = 365/869 (42%), Gaps = 228/869 (26%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGP------- 619 G+PG G+ G+ G G+ G PG PG+PG G+ G GP+G G G PG +GP Sbjct: 753 GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812 Query: 620 -------------MGQRGREGPMGPRGEAGPPG---------------------SGEKGE 645 GQ+GR G GP+G+ G PG G G+ Sbjct: 813 PRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ 872 Query: 646 RGAAGEPGPHGPP---------GVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGV 696 RG G PG GPP G PG++GP G G+PG G G G+ G++G+ G PG Sbjct: 873 RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932 Query: 697 KGDKGPMGPPGPK------GDQGEKGPRGLTGEP---GMRGLPGAVGEPGAKGAMGPAGP 747 KG++G G PGP GD+GE G +G G P G RG+PG G G KG GPAGP Sbjct: 933 KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992 Query: 748 DGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGK 807 G +G G G G PG+RG PG G+ G PG G +G G PG GRPG+ G G G Sbjct: 993 PGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGD 1052 Query: 808 IVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGP 867 G S T PGPPGP G G PG G G G G PGH GP GP G G Sbjct: 1053 -KGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGH------LGPAGPEGAPGS 1105 Query: 868 PG-PSIPGPPGPRGPPG----EGLPGPP---GPPGSFLSNSETFLSGPPGPPGPPGPKGD 919 PG P +PG PGP G G +GL GPP GPPG L G PG PGP G +GD Sbjct: 1106 PGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPG---------LPGFPGSPGPMGIRGD 1156 Query: 920 QGP---PGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGP---PGPQGPKGDKGDPGVPGA 973 QG PGP G +GE GL L+ PPGP PG QG KGD+G PG PG Sbjct: 1157 QGRDGIPGPAGEKGETGL--------------LRAPPGPRGNPGAQGAKGDRGAPGFPGL 1202 Query: 974 LGIPSGPSEGGSSSTMYVSGPPGPPGPPGP--PGSISSSGQEIQQYISEYMQSDSIRSYL 1031 G + G + G PGPPG PG PG + G Sbjct: 1203 PGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGP------------------- 1243 Query: 1032 SGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVL 1091 G +G PG PGPPGP SHV+ G Sbjct: 1244 PGSRGSPGAPGPPGPP-------------GSHVIGIKGDKG------------------- 1271 Query: 1092 QRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPP 1151 MG GP GPPG +GD M G +G PG P Sbjct: 1272 ------------SMGHPGPKGPPGTAGD------------------MGPPG-RLGAPGTP 1300 Query: 1152 GPPGLPGTSYEELLSLLRGSE----FRGIVGPPGPPGPPGIPG-----NVWSSISVEDLS 1202 G PG G + ++G + F G +GPPGP GP G PG IS+ Sbjct: 1301 GLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSP 1360 Query: 1203 SYLHTAGLSFIPGPPGPPGPP------GPRGPPGVSGALATYAAENSDSFRSELISYLTS 1256 T G + G PGPPGPP GPRG PG G T + Sbjct: 1361 GPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGS------- 1413 Query: 1257 PDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVR----RGSSYSSSMS 1312 G PGP G G PG RG S S + + R S ++++ Sbjct: 1414 -------KGEPGPAGSDGLPG--------LKGKRGDSGSPATWTTRGFVFTRHSQTTAIP 1458 Query: 1313 TGGGGAGSLGAGGAFGEAAGDRGPYGTDI 1341 + G L +G +F G++ +G D+ Sbjct: 1459 SCPEGTVPLYSGFSFLFVQGNQRAHGQDL 1487 Score = 379 bits (974), Expect = e-105 Identities = 272/739 (36%), Positives = 316/739 (42%), Gaps = 195/739 (26%) Query: 566 RGSPGPKGDMGSPGPKGDR-GFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 RG GPKGD G PG DR GFPG G PG GH G GP GQ+G G+PG+ GP G+ G Sbjct: 832 RGKTGPKGDPGIPGL--DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889 Query: 625 REGPMGPRGEAGPPGS----GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQ---- 676 G MG G GPPG G G+RG+ G PG G G PG+ G +G G+PGP Sbjct: 890 VIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949 Query: 677 --GPPGPVGLQGL---------RGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPG 725 G G GL+G RG G+PG+KG KG GP GP G +G+ G G GEPG Sbjct: 950 VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009 Query: 726 MRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRG--------------PPGP 771 +RG+PG++G G G+ G G G G G GL G+ G++G PPGP Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP 1069 Query: 772 SGDPG---------------KPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSM 816 +GDPG PG GP GP+G PG+PG PG+ G+PG G + Sbjct: 1070 TGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL------GF 1123 Query: 817 LTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPG----------PPGPRG 866 + G GPPG GPPG PG PG GP G+ G Q + GP G PPGPRG Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRG 1183 Query: 867 PPGPSIPGPPGPRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGP-----KGDQ 920 PG G G RG PG GLPG G G T + G PGPPG PG G++ Sbjct: 1184 NPGAQ--GAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNR 1241 Query: 921 GPPGPRGHQGEQGLPGFSTSGSSSFGLNL-QGPPGPPGPQGPKGDKGDPGVPGALGIPSG 979 GPPG RG G G PG GS G+ +G G PGP+GP G GD G PG LG P Sbjct: 1242 GPPGSRGSPGAPGPPG--PPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGT 1299 Query: 980 PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPG 1039 P G G PG G G PG + S G G +GPPG Sbjct: 1300 PGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGP----------------IGPKGPPG 1343 Query: 1040 PPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQY 1099 G PG + I+ Sbjct: 1344 VRGDPGTLKIIS------------------------------------------------ 1355 Query: 1100 LRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGT 1159 L G GPPG PG G G PGPPGPPG G Sbjct: 1356 ----LPGSPGPPGTPGEPG-------------------------MQGEPGPPGPPGNLGP 1386 Query: 1160 SYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGP 1219 RG G G PG PGP G GN G PGP G Sbjct: 1387 CGP------RGKP--GKDGKPGTPGPAGEKGN----------------KGSKGEPGPAGS 1422 Query: 1220 PGPPGPRGPPGVSGALATY 1238 G PG +G G SG+ AT+ Sbjct: 1423 DGLPGLKGKRGDSGSPATW 1441 Score = 337 bits (865), Expect = 4e-92 Identities = 234/601 (38%), Positives = 268/601 (44%), Gaps = 136/601 (22%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 L GS G +G G PG G G PGTPG GP G G G G KG G PG+ G +G G Sbjct: 86 LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145 Query: 625 REGPMGPRGEAGPPGSGE------KGERGAAGEPGPH---GPPGVPGSVGPKGSS---GS 672 G G +G+ G P E KG+ G G PGP GPPG PG VGP G G Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205 Query: 673 PGPQGPPGPV--------------GLQGLRGEVGLPGV-----------------KGDKG 701 PG GP GP G++GL G G PG KGDKG Sbjct: 206 PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265 Query: 702 PMGPPGPKG-----------DQGEKGPRGLTGEPGM---------------RGLPGAVGE 735 MG PGP G ++G G GL G+PG RG PG +GE Sbjct: 266 AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325 Query: 736 PGAKGAMGPAGPDGHQGP---------RGEQGLTGMP---GIRGPPGPSGDPGKPGLTGP 783 G KG G GP G +GP +G++G G P G RGP GPSG PG PG G Sbjct: 326 DGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385 Query: 784 QGP--QGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPG----A 837 P +G PG PG G KGE G PGK S G PG PG+ GPPGPPG Sbjct: 386 SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSP-GCAGSPGLPGSPGPPGPPGDIVFR 444 Query: 838 PGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG------PSIPGPPGPRGPPG----EGLP 887 GP G GLPG+ L G PG GP+G PG P IPGPPG G PG +G+P Sbjct: 445 KGPPGDHGLPGY---LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP 501 Query: 888 GPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGH----QGEQGLPGFSTSGSS 943 G G G S +G PG PG PG +GD G G +G +G+ G+PG Sbjct: 502 GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQ 561 Query: 944 SFGLNLQGPPGPP------------------GPQGPKGDKGDPGVPGALGIPSGPSEGGS 985 L G PG P G QGP GD G PG PG G P+GP G Sbjct: 562 PGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAG-PAGPPGYGP 620 Query: 986 SSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPG 1045 + G G PG PGPPG G+ S+ + + G GPPGPPG PG Sbjct: 621 QGEPGLQGTQGVPGAPGPPGEAGPRGEL------------SVSTPVPGPPGPPGPPGHPG 668 Query: 1046 P 1046 P Sbjct: 669 P 669 Score = 329 bits (843), Expect = 1e-89 Identities = 307/896 (34%), Positives = 360/896 (40%), Gaps = 162/896 (18%) Query: 692 GLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQ 751 G G KG+KG GPPG G +G GP GL G G +G PG G G+KG G +G G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 752 GPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGI------KGEPGAP 805 G GL G PG GP G G PG G G QG GLPGT G PGI KG+ GAP Sbjct: 103 G---SPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAP 159 Query: 806 GKIVTSEGSSMLTVPGPPGPPGAMGP---PGPPGAPGPAGPAGLPGHQEVLNLQGPPGPP 862 K E L G PG PGA GP PGPPG PGP GP G PG G GP Sbjct: 160 AK----EEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPG---FFGFPGAMGPR 212 Query: 863 GPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFL--------------SNSETFLSGPP 908 GP+G G + G G RG +GL GPPGPPG+ + + G P Sbjct: 213 GPKGHMGERVIGHKGERGV--KGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEP 270 Query: 909 GPPGPPG--------PKGDQGPPGPRGHQGEQGLPGFSTS----GSSSF-GL-------N 948 GPPGP G KG G PG +G G+ G+PGF S G+ F GL Sbjct: 271 GPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKG 330 Query: 949 LQGPPGPPGPQGP---------KGDKGDPGVPGALGI-----PSGPSEGGSSSTMYVSGP 994 +G GPPG +GP KGD+G PG PG G PSGP S G Sbjct: 331 QKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGL 390 Query: 995 PGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGET 1054 G PG PG GS G+ + + S G+ G PGPPGPPG + G Sbjct: 391 RGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGS--PGLPGSPGPPGPPGDIVFRKGPP 448 Query: 1055 FDYSELASHVVSYLRTSGY-GVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGP 1113 D+ + YL + G GV E L Q Y+ GP G PG Sbjct: 449 GDHG-----LPGYLGSPGIPGV----DGPKGEPGLLCTQ--------CPYIPGPPGLPGL 491 Query: 1114 PGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSL------ 1167 PG G + A ++G+ G PG PG G PG E+ +L Sbjct: 492 PGLHGVKGIPGRQGAAGLKGSPGSPGNTGLP-GFPGFPGAQGDPGLKGEKGETLQPEGQV 550 Query: 1168 -------LRGSEFR-GIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGP 1219 LRG R G+ G PG PG G+PG LS G PG PG Sbjct: 551 GVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELA----LSGEKGDQGPPGDPGSPGS 606 Query: 1220 PGPPGPRGPP-----------GVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPG 1268 PGP GP GPP G G R EL V + + GPPG Sbjct: 607 PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGEL-------SVSTPVPGPPG 659 Query: 1269 PPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGG--------GGAGS 1320 PPGP G PG S + G G G GS Sbjct: 660 PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719 Query: 1321 LGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRV 1380 LG G GE G G G G G A GG G G G + ++ E+ + Sbjct: 720 LGCPGKMGE-PGLPGKPGLP-GAKGEPAVAMPGG--PGTPGFPG-ERGNSGEHGEIGLPG 774 Query: 1381 SESMQRQGLLQGMAYTVQGPPGQPGP---QGPPG--ISKVFSAYSNVTADLMDFFQTYGA 1435 + +G+ +G PGQPGP QGPPG I A Q Sbjct: 775 LPGLPGTPGNEGLD-GPRGDPGQPGPPGEQGPPGRCIEGPRGA------------QGLPG 821 Query: 1436 IQGPPGQKGEMGTPGPKGDRG-----PAGPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 + G GQ+G G GPKGD G +G PG G PG GH+GE G G + Y G Sbjct: 822 LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPG 877 Score = 310 bits (795), Expect = 5e-84 Identities = 186/424 (43%), Positives = 219/424 (51%), Gaps = 47/424 (11%) Query: 563 GNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGP--- 619 G G PGP GD G PG G +G G PG PG LG GP+G G GS G PG GP Sbjct: 1061 GTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGD 1120 Query: 620 MGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSG----SPG 674 +G +G +G +GP G GPPG G G G G G G G+PG G KG +G PG Sbjct: 1121 LGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPG 1180 Query: 675 PQGPPGPVGLQGLRGEVGLPGVKGDKGPM---GPPGPKGDQGEKGPRGLTGE--PGMRGL 729 P+G PG G +G RG G PG+ G KG M GP GP G +G GP GL G PG G Sbjct: 1181 PRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGN 1240 Query: 730 PGAVGEPGAKGAMGPAGPDGHQ--GPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQ 787 G G G+ GA GP GP G G +G++G G PG +GPPG +GD G PG G G Sbjct: 1241 RGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTP 1300 Query: 788 GLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLP 847 GLPG G PG +G PG G+ G PG G++GPPGP G GP G G P Sbjct: 1301 GLPGPRGDPGFQGFPGVKGE------------KGNPGFLGSIGPPGPIGPKGPPGVRGDP 1348 Query: 848 GHQEVLNLQGPPGPPGPRGPPG----PSIPGPP------GPRGPPG-EGLPGPPGPPGSF 896 G ++++L G PGPPG G PG P PGPP GPRG PG +G PG PGP G Sbjct: 1349 GTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGE- 1407 Query: 897 LSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPP 956 G G G PGP G G PG +G +G+ G P T+ F + Q P Sbjct: 1408 --------KGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPS 1459 Query: 957 GPQG 960 P+G Sbjct: 1460 CPEG 1463 Score = 303 bits (777), Expect = 6e-82 Identities = 284/868 (32%), Positives = 335/868 (38%), Gaps = 232/868 (26%) Query: 705 PPGPKG----DQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLT 760 P KG D+G+ G GE G +G PG G PG KG GP G G QGP+G GL Sbjct: 25 PAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLP 84 Query: 761 GMPG------IRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGS 814 G+ G I G PG SG PG PG G GP GL G PG G KGE G PG Sbjct: 85 GLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGL------- 137 Query: 815 SMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNL--QGPPGPPGPRGPPGPSI 872 PG +G PG PGA G G G P +E + L +G PG PG GP G + Sbjct: 138 -----------PGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQG--L 184 Query: 873 PGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQ 932 PGPPG GP G PPGPPG F G PG GP GPKG G GH+GE+ Sbjct: 185 PGPPGFPGPVG-----PPGPPGFF---------GFPGAMGPRGPKGHMGER-VIGHKGER 229 Query: 933 GLPGFSTSGSSSFGLNLQGPPGPPGP--------------QGPKGDKG---DPGVPGALG 975 G+ G L GPPGPPG +G KGDKG +PG PG G Sbjct: 230 GVKG------------LTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSG 277 Query: 976 IPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQ 1035 +P G S G G G PG G PG S G + + M D I+ G + Sbjct: 278 LP-GESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIK----GQK 332 Query: 1036 GPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDD 1095 G GPPG GP E +D +Y G + Sbjct: 333 GDIGPPGFRGPT-----EYYD---------TYQEKGDEGTPGPPGPRGAR---------- 368 Query: 1096 VRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPG 1155 GP+GP GPPG G SSR GL G PG PG Sbjct: 369 ----------GPQGPSGPPGVPGSPG---------SSRP-----------GLRGAPGWPG 398 Query: 1156 LPGTSYE------ELLSLLRGSEFRGIVGPPGPPGPPGIPGNVW---SSISVEDLSSYLH 1206 L G+ E + + G G PG PGPPG PG++ L YL Sbjct: 399 LKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLG 458 Query: 1207 TAGLS-----------------FIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSE 1249 + G+ +IPGPPG PG PG G G+ G + S Sbjct: 459 SPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPG---- 514 Query: 1250 LISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSS 1309 SP + + G PG PG QG PG + + G +R G Sbjct: 515 ------SPG-NTGLPGFPGFPGAQGDPG-LKGEKGETLQPEGQVGVPGDPGLR-GQPGRK 565 Query: 1310 SMSTGGGGAGSLGAGGAFGEAA-----GDRGPYGTDIGPGG----------GYGAAAEGG 1354 + G G G G GE A GD+GP G PG GYG E G Sbjct: 566 GLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625 Query: 1355 MYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISK 1414 + G G+ GA E+ R L ++ V GPPG PGP G PG Sbjct: 626 LQ-GTQGVPGAPGPP-----------GEAGPRGEL--SVSTPVPGPPGPPGPPGHPGP-- 669 Query: 1415 VFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPG-----HPGPPGP 1469 QGPPG G +G G G GP G PG PGPPGP Sbjct: 670 ----------------------QGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 707 Query: 1470 RGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 +G +G G KG G+ + KP Sbjct: 708 KGDQGFPGTKGSLGCPGKMGEPGLPGKP 735 Score = 236 bits (601), Expect = 2e-61 Identities = 127/273 (46%), Positives = 154/273 (56%), Gaps = 23/273 (8%) Query: 561 ENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPG---PLGHPGPQGPKGQKGSVGDPGME 617 E G LR PGP+G+ G+ G KGDRG PG PG+PG +G GP+GP G +G G PG+ Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230 Query: 618 GPM--GQRGREGPMGPRGEAG------PPGS---GEKGERGAAGEPGPHGPPGVPGSVGP 666 G + GQ G GP G RG G PPGS G KG++G+ G PGP GPPG G +GP Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290 Query: 667 ------KGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRG- 719 G+ G PGP+G PG G G++GE G PG G GP GP GPKG G +G G Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGT 1350 Query: 720 --LTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGK 777 + PG G PG GEPG +G GP GP G+ GP G +G G G G PGP+G+ G Sbjct: 1351 LKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGN 1410 Query: 778 PGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVT 810 G G GP G G PG G +G+ G+P T Sbjct: 1411 KGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTT 1443 Score = 113 bits (282), Expect = 2e-24 Identities = 60/121 (49%), Positives = 70/121 (57%), Gaps = 8/121 (6%) Query: 559 EQENGNLRGSPGPKGDMGSPGPKGDRGFPGT------PGIPGPLGHPGPQGPKGQKGSVG 612 E+ N GS GP G +G GP G RG PGT PG PGP G PG G +G+ G G Sbjct: 1320 EKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPG 1379 Query: 613 DPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGS 672 PG GP G RG+ G G G GP +GEKG +G+ GEPGP G G+PG G +G SGS Sbjct: 1380 PPGNLGPCGPRGKPGKDGKPGTPGP--AGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGS 1437 Query: 673 P 673 P Sbjct: 1438 P 1438 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 453 bits (1165), Expect = e-127 Identities = 385/1131 (34%), Positives = 454/1131 (40%), Gaps = 264/1131 (23%) Query: 560 QENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPL--------GHPGPQGPKGQKG-- 609 QE G+ G+PGP G G+ GP+G G PG PG PG G PG +G KG++G Sbjct: 351 QEKGD-EGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRP 409 Query: 610 ------SVGDPGMEGPMGQRGREGPMGPRGEA----GPPGS----------GEKGERGAA 649 + G PG G G G GP GP G+ GPPG G G G Sbjct: 410 GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPK 469 Query: 650 GEPG------PH--GPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKG 701 GEPG P+ GPPG+PG G G G PG QG G G G G GLPG G G Sbjct: 470 GEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPG 529 Query: 702 PMGPPGPKGDQGEK----------GPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQ 751 G PG KG++GE G GL G+PG +GL G G PG KG GP G Sbjct: 530 AQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALS 589 Query: 752 GPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTS 811 G +G+QG G PG G PGP+G G PG GPQG GL GT G PG G PG G Sbjct: 590 GEKGDQGPPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVPGAPGPPGEAGP--RG 646 Query: 812 EGSSMLTVPGPPGPPGAMGPPGP--------------------------------PGAPG 839 E S VPGPPGPPG G PGP PG PG Sbjct: 647 ELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPG 706 Query: 840 PAGPAGLPGHQEVLN---------LQGPPGPPGPRGPPGPSIPGPPGPRGPPGE------ 884 P G G PG + L L G PG PG +G P ++PG PG G PGE Sbjct: 707 PKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGE 766 Query: 885 ----GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPG-----PRGHQG----- 930 GLPG PG PG+ L GP G PG PGP G+QGPPG PRG QG Sbjct: 767 HGEIGLPGLPGLPGT---PGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLN 823 Query: 931 ----------------EQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGAL 974 + G+PG SG G PG G GP G +G PG PG L Sbjct: 824 GLKGQQGRRGKTGPKGDPGIPGLDRSGFPG-ETGSPGIPGHQGEMGPLGQRGYPGNPGIL 882 Query: 975 GIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSG----------------------- 1011 G P G GPPGPPG PG PG S G Sbjct: 883 GPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNP 942 Query: 1012 --QEIQQYISEYMQSDSIRSY-----------------LSGVQGPPGPPGPPGPVTTITG 1052 EI I + + ++ + L G++G PGP GPPGP + G Sbjct: 943 GPSEISHVIGDKGEP-GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL-G 1000 Query: 1053 ETFDYSELASH-VVSYLRTSGY-------GVSLFSSSISSEDILAV--LQRDDVRQ-YLR 1101 T + E + + G G F + + LQ D Y Sbjct: 1001 STGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSE 1060 Query: 1102 QYLMGPRGPPGPPGASGDGSLLSLDYAELSSR-ILSYMSSSGISIGLPGPPGPPGLPGTS 1160 GP GP G PG GD E+ ++ +G G PG PG PGLPG Sbjct: 1061 GTRPGPPGPTGDPGLPGDMG----KKGEMGQPGPPGHLGPAGPE-GAPGSPGSPGLPGKP 1115 Query: 1161 YEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPP 1220 +G +G++GPPG GPPG+PG S + G IPGP G Sbjct: 1116 GPHGDLGFKG--IKGLLGPPGIRGPPGLPGFPGSPGPM----GIRGDQGRDGIPGPAGEK 1169 Query: 1221 G-------PPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQ 1273 G PPGPRG PG GA A R +G GP GP Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPG-----------RKGAMGDAGPRGPT 1218 Query: 1274 G------PPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAF 1327 G PPG + + +RG S RGS + G G+ +G G Sbjct: 1219 GIEGFPGPPGLPGAIIPGQTGNRGPPGS-------RGSPGAPG-PPGPPGSHVIGIKGDK 1270 Query: 1328 GEAA--GDRGPYGT--DIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSES 1383 G G +GP GT D+GP G GA G+ G F G V Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG----------VKGE 1320 Query: 1384 MQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYG--AIQGPPG 1441 G L + GPPG GP+GPPG+ T ++ + G G PG Sbjct: 1321 KGNPGFLGSI-----GPPGPIGPKGPPGVRG-----DPGTLKIISLPGSPGPPGTPGEPG 1370 Query: 1442 QKGEMGTPGPKGDRGPAGP------PGHPGPPGPRGHKGEKGDKGDQVYAG 1486 +GE G PGP G+ GP GP G PG PGP G KG KG KG+ AG Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAG 1421 Score = 449 bits (1156), Expect = e-126 Identities = 354/1008 (35%), Positives = 421/1008 (41%), Gaps = 185/1008 (18%) Query: 563 GNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHP---GPQGPKGQKGSVGDPGME-- 617 G+ +G+PG G G PG G GFPG+ G+ G G P G G KGQKG +G PG Sbjct: 284 GSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGP 343 Query: 618 -------------------GPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPG----- 653 GP G RG +GP GP G G PGS G RGA G PG Sbjct: 344 TEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSK 403 Query: 654 ---------PHGPPGVPGSVGPKGSSGSPGPQGPP-------GPVGLQGLRGEVGLPGVK 697 G PG PG G G GSPGP GPP GP G GL G +G PG+ Sbjct: 404 GERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIP 463 Query: 698 GDKGPMGPPGPKGDQ-----GEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQG 752 G GP G PG Q G G GL G G++G+PG G G KG+ G G G G Sbjct: 464 GVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPG 523 Query: 753 PRGEQGLTGMPGIRG-------PPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAP 805 G G G PG++G P G G PG PGL G G +GL G PG PG+KG PG Sbjct: 524 FPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPK 583 Query: 806 GKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPR 865 G++ S PG PG PG+ GP GP G PG GP G PG Q + G PGPPG Sbjct: 584 GELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGTQGVPGAPGPPGEA 642 Query: 866 GPPG-----PSIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGD 919 GP G +PGPPGP GPPG G GPPG PGS + L GP G PG PG G Sbjct: 643 GPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG-IGF 701 Query: 920 QGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGV--PGALGIP 977 GPPGP+ G+QG PG T GS G PG PG G G KG+P V PG G P Sbjct: 702 PGPPGPK---GDQGFPG--TKGSLGCP-GKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTP 755 Query: 978 SGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGP 1037 P E G+S G PG PG PG PG+ G G G Sbjct: 756 GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR-------------------GDPGQ 796 Query: 1038 PGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVR 1097 PGPPG GP G + A + G Sbjct: 797 PGPPGEQGP----PGRCIEGPRGAQGLPGLNGLKG------------------------- 827 Query: 1098 QYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLP 1157 Q R+ GP+G PG PG G S I + G +G G PG PG+ Sbjct: 828 QQGRRGKTGPKGDPGIPGLDRSG----FPGETGSPGIPGHQGEMG-PLGQRGYPGNPGIL 882 Query: 1158 GTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPP 1217 G E+ + + G F G +GPPGPPG PG PG S + + T G G Sbjct: 883 GPPGEDGVIGMMG--FPGAIGPPGPPGNPGTPGQ-RGSPGIPGVKGQRGTPGAKGEQGDK 939 Query: 1218 GPPGPP------GPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPG 1271 G PGP G +G PG+ G + + P ++ + G PGP G Sbjct: 940 GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG-------MPGLKG-LKGLPGPAG 991 Query: 1272 PQGPPGDSRLLSTDASHSRGSSSSSHSSSVR--RGSSYSSSMSTGGGGAGSLGAGGAFGE 1329 P GP GD GS+ + +R GS + M G G+LG G G Sbjct: 992 PPGPRGD-----------LGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR 1040 Query: 1330 AA--GDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQ 1387 G G G PG G G+ GL GD+ M + Sbjct: 1041 PGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL-----PGDMG-------KKGEMGQP 1088 Query: 1388 GLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMG 1447 G + GP G PG G PG+ + ++ + I+GPPG G G Sbjct: 1089 GPPGHLG--PAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPG 1146 Query: 1448 TPGPKGDRGPAGPPGHPG-------------PPGPRGHKGEKGDKGDQ 1482 +PGP G RG G G PG PPGPRG+ G +G KGD+ Sbjct: 1147 SPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDR 1194 Score = 442 bits (1137), Expect = e-123 Identities = 357/1038 (34%), Positives = 431/1038 (41%), Gaps = 205/1038 (19%) Query: 572 KGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQR--GREGPM 629 KGD G PG G +G PG PG PGP+G PGP G G G++G G +G MG+R G +G Sbjct: 170 KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGER 229 Query: 630 GPRGEAGPPG------------------SGEKGERGAAGEPGPHGPPGVPGSV--GPKGS 669 G +G GPPG GEKG++GA GEPGP GP G+PG KG+ Sbjct: 230 GVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGA 289 Query: 670 SGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTG------- 722 G PG QG PG G+ G G G+ G +G G MG G KG +G+ GP G G Sbjct: 290 PGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDT 349 Query: 723 --EPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGE-----QGLTGMPGIRGPPGPSGDP 775 E G G PG G GA+G GP+GP G G G +G G PG++G G G P Sbjct: 350 YQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRP 409 Query: 776 GKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGS-------------SMLTVPGP 822 GK + P P G G+PG PG G PG PG IV +G + V GP Sbjct: 410 GKDAMGTPGSP-GCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGP 468 Query: 823 PGPPGAM--------GPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG----- 869 G PG + GPPG PG PG G G+PG Q L+G PG PG G PG Sbjct: 469 KGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFP 528 Query: 870 ---------------------PSIPGPPGPRGPPG----EGLPGPPG------PPGSFLS 898 +PG PG RG PG +G+PG PG P G Sbjct: 529 GAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELAL 588 Query: 899 NSETFLSGPPGPPGPPGPKGDQGPPGPRGH--------QGEQGLPGF-------STSGSS 943 + E GPPG PG PG G GP GP G+ QG QG+PG G Sbjct: 589 SGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGEL 648 Query: 944 SFGLNLQGPPGPPGPQGPKGDKGDPGVPGALG------IPSGPSEGGSSSTMYVSGPPGP 997 S + GPPGPPGP G G +G PG+PG+LG +P E G + GPPGP Sbjct: 649 SVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF-PGPPGP 707 Query: 998 PGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDY 1057 G G PG+ S G G G PG PG PG + G Sbjct: 708 KGDQGFPGTKGSLG-------------------CPGKMGEPGLPGKPG----LPGAK--- 741 Query: 1058 SELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGAS 1117 E A + T G+ +S E L L + L GPRG PG PG Sbjct: 742 GEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPG-NEGLDGPRGDPGQPGPP 800 Query: 1118 GDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIV 1177 G+ G I GP G GLPG L+ L+G + G Sbjct: 801 GE------------------QGPPGRCI--EGPRGAQGLPG------LNGLKGQQ--GRR 832 Query: 1178 GPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALAT 1237 G GP G PGIPG D S + G IPG G GP G RG PG G L Sbjct: 833 GKTGPKGDPGIPG--------LDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884 Query: 1238 YAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSH 1297 + +I + P +GPPGPPG G PG + + + Sbjct: 885 PGEDG-------VIGMMGFPGA----IGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAK 933 Query: 1298 SSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPG--GGYGAAAEGGM 1355 +G+ S +S G G G G F G++G G PG G G G Sbjct: 934 GEQGDKGNPGPSEISHVIGDKGEPGLKG-FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992 Query: 1356 YAGNGGLLGADFAGDLDYNELAVRVSESMQRQGL--LQGMAYTVQGPPGQPGPQGPPGI- 1412 G L G+ + SM G+ +G T+ G PG+ G G PGI Sbjct: 993 PGPRGDLGSTGNPGEPGLR----GIPGSMGNMGMPGSKGKRGTL-GFPGRAGRPGLPGIH 1047 Query: 1413 ----SKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPG 1468 K YS T + G G+KGEMG PGP G GPAGP G PG PG Sbjct: 1048 GLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPG 1107 Query: 1469 PRGHKGEKGDKGDQVYAG 1486 G G+ G GD + G Sbjct: 1108 SPGLPGKPGPHGDLGFKG 1125 Score = 419 bits (1076), Expect = e-116 Identities = 349/1025 (34%), Positives = 410/1025 (40%), Gaps = 238/1025 (23%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGH------PGPQGPKGQKGSVGDPGMEGP 619 +G G KG G PG G +GF G G+PGP G PG G KG +G G PG G Sbjct: 45 KGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGS 104 Query: 620 MGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSP----- 673 G G G GP G G PG SG KGE+G G PG G PG+PG+ G KG G+P Sbjct: 105 PGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164 Query: 674 ---------------GPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGE---- 714 GPQG PGP G G G G PG G G MGP GPKG GE Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIG 224 Query: 715 -KGPRGLTGEPGMRGLPGAV--------------GEPGAKGAMGPAGPDGHQGPRGE--- 756 KG RG+ G G G PG V GE G KGAMG GP G G GE Sbjct: 225 HKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYG 284 Query: 757 --QGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGS 814 +G G PG++G PG G PG PG G +G +G PG G GIKG+ G G + Sbjct: 285 SEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPT 344 Query: 815 SMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGP--PGPRGPPG-PS 871 G G GPPGP GA GP GP+G PG + G PG PG RG PG P Sbjct: 345 EYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPG------VPGSPGSSRPGLRGAPGWPG 398 Query: 872 IPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGD----QGPPGPRG 927 + G G RG PG+ G PG PG S G PG PGPPGP GD +GPPG G Sbjct: 399 LKGSKGERGRPGKDAMGTPGSPGCAGS------PGLPGSPGPPGPPGDIVFRKGPPGDHG 452 Query: 928 ---HQGEQGLPGFSTSGSSSFGLNLQ-----GPPGPPGPQGPKGDKGDPGVPGALGIPSG 979 + G G+PG L Q GPPG PG G G KG PG GA G+ Sbjct: 453 LPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGS 512 Query: 980 PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSI------RSYLSG 1033 P G++ + G PG PG G PG G+ +Q + D R L G Sbjct: 513 PGSPGNTG---LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDG 569 Query: 1034 VQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQR 1093 + G PG G PGP ELA +S E Sbjct: 570 IPGTPGVKGLPGPK----------GELA--------------------LSGEK------- 592 Query: 1094 DDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGP 1153 G +GPPG PG+ G PGP GP Sbjct: 593 ------------GDQGPPGDPGSPGS----------------------------PGPAGP 612 Query: 1154 PGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFI 1213 G PG + L +G++ G+ G PGPPG G G + S V Sbjct: 613 AGPPGYGPQGEPGL-QGTQ--GVPGAPGPPGEAGPRGELSVSTPVPGP------------ 657 Query: 1214 PGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVG-----PPG 1268 PGPPGPPG PGP+GPPG+ G+L L PD I G PPG Sbjct: 658 PGPPGPPGHPGPQGPPGIPGSLGKCGDPG-----------LPGPDGEPGIPGIGFPGPPG 706 Query: 1269 PPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFG 1328 P G QG PG L +G + +M G G G G G G Sbjct: 707 PKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEP-AVAMPGGPGTPGFPGERGNSG 765 Query: 1329 EAA-----------GDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELA 1377 E G G G D GP G G G G + Sbjct: 766 EHGEIGLPGLPGLPGTPGNEGLD-GPRGDPGQPGPPGEQGPPGRCIEGP----------- 813 Query: 1378 VRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVF-SAYSNVTADL---------- 1426 R ++ + L+G QG G+ GP+G PGI + S + T Sbjct: 814 -RGAQGLPGLNGLKGQ----QGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMG 868 Query: 1427 ---MDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQV 1483 + I GPPG+ G +G G G GP GPPG+PG PG RG G G KG + Sbjct: 869 PLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRG 928 Query: 1484 YAGRR 1488 G + Sbjct: 929 TPGAK 933 Score = 418 bits (1075), Expect = e-116 Identities = 349/1036 (33%), Positives = 415/1036 (40%), Gaps = 262/1036 (25%) Query: 560 QENGNLRGSPG----PKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQG---PKGQKGSVG 612 Q + L+G G P+G +G PG G RG PG G+ G G PG +G PKG+ G Sbjct: 531 QGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSG 590 Query: 613 DPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGE---RGAAGEPGPHGPPG---------- 659 + G +GP G G G GP G AGPPG G +GE +G G PG GPPG Sbjct: 591 EKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV 650 Query: 660 ---VPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGP-----MGPPGPKGD 711 VPG GP G G PGPQGPPG G G G+ GLPG G+ G GPPGPKGD Sbjct: 651 STPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGD 710 Query: 712 QGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMG------PAGPD--------GHQGPRGEQ 757 QG G +G G PG G PG G+PG GA G P GP G+ G GE Sbjct: 711 QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770 Query: 758 GLTGMPGIRGPP------GPSGDPGKPG-----------LTGPQGPQGLP---------G 791 GL G+PG+ G P GP GDPG+PG + GP+G QGLP G Sbjct: 771 GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830 Query: 792 TPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQE 851 G+ G KG+PG PG + S PG PG G MGP G G PG G G PG Sbjct: 831 RRGKTGPKGDPGIPG-LDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889 Query: 852 VLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGP- 910 V+ + G PG GP GPPG PG PG RG P G+PG G G+ + E G PGP Sbjct: 890 VIGMMGFPGAIGPPGPPGN--PGTPGQRGSP--GIPGVKGQRGTPGAKGEQGDKGNPGPS 945 Query: 911 --------PGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGL-NLQGPPGPPGPQGP 961 G PG KG G PG +G++G G+PG GL L GP GPPGP+G Sbjct: 946 EISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLK-------GLKGLPGPAGPPGPRGD 998 Query: 962 KGDKGDPGVPGALGIPSG------PSEGGSSSTMYV------------------------ 991 G G+PG PG GIP P G T+ Sbjct: 999 LGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGY 1058 Query: 992 -----SGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGP 1046 GPPGP G PG PG + G+ Q ++ +G +G PG PG PG Sbjct: 1059 SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGP-------AGPEGAPGSPGSPG- 1110 Query: 1047 VTTITGETFDYSELA-SHVVSYLRTSGY----GVSLFSSSISSEDILAVLQRDDV----- 1096 + G+ + +L + L G G+ F S I RD + Sbjct: 1111 ---LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAG 1167 Query: 1097 ---RQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGP 1153 L + GPRG PG GA GD + G G+ G PGP Sbjct: 1168 EKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRG-PTGIEGFPGP 1226 Query: 1154 PGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPP-----GIPGNVWSSISVEDLSSYLHTA 1208 PGLPG RG G PGPPGPP GI G+ S+ TA Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK-GSMGHPGPKGPPGTA 1285 Query: 1209 GLSFIP---GPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVG 1265 G P G PG PG PGPRG PG G + + F +G Sbjct: 1286 GDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS--------------IG 1331 Query: 1266 PPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGG 1325 PPGP GP+GPPG RG G+ S+ G G+ G G Sbjct: 1332 PPGPIGPKGPPG-----------VRGDP----------GTLKIISLPGSPGPPGTPGEPG 1370 Query: 1326 AFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQ 1385 GE G GP G ++GP G G + Sbjct: 1371 MQGE-PGPPGPPG-NLGPCGPRGKPGK--------------------------------- 1395 Query: 1386 RQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGE 1445 G PG PGP G G +G PG G Sbjct: 1396 ------------DGKPGTPGPAGEKGNK---------------------GSKGEPGPAGS 1422 Query: 1446 MGTPGPKGDRGPAGPP 1461 G PG KG RG +G P Sbjct: 1423 DGLPGLKGKRGDSGSP 1438 Score = 413 bits (1062), Expect = e-115 Identities = 304/873 (34%), Positives = 367/873 (42%), Gaps = 228/873 (26%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGP------- 619 G+PG G+ G+ G G+ G PG PG+PG G+ G GP+G G G PG +GP Sbjct: 753 GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812 Query: 620 -------------MGQRGREGPMGPRGEAGPPG---------------------SGEKGE 645 GQ+GR G GP+G+ G PG G G+ Sbjct: 813 PRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ 872 Query: 646 RGAAGEPGPHGPP---------GVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGV 696 RG G PG GPP G PG++GP G G+PG G G G+ G++G+ G PG Sbjct: 873 RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932 Query: 697 KGDKGPMGPPGPK------GDQGEKGPRGLTGEP---GMRGLPGAVGEPGAKGAMGPAGP 747 KG++G G PGP GD+GE G +G G P G RG+PG G G KG GPAGP Sbjct: 933 KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992 Query: 748 DGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGK 807 G +G G G G PG+RG PG G+ G PG G +G G PG GRPG+ G G G Sbjct: 993 PGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGD 1052 Query: 808 IVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGP 867 G S T PGPPGP G G PG G G G G PGH GP GP G G Sbjct: 1053 -KGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGH------LGPAGPEGAPGS 1105 Query: 868 PG-PSIPGPPGPRGPPG----EGLPGPP---GPPGSFLSNSETFLSGPPGPPGPPGPKGD 919 PG P +PG PGP G G +GL GPP GPPG L G PG PGP G +GD Sbjct: 1106 PGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPG---------LPGFPGSPGPMGIRGD 1156 Query: 920 QGP---PGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGP---PGPQGPKGDKGDPGVPGA 973 QG PGP G +GE GL L+ PPGP PG QG KGD+G PG PG Sbjct: 1157 QGRDGIPGPAGEKGETGL--------------LRAPPGPRGNPGAQGAKGDRGAPGFPGL 1202 Query: 974 LGIPSGPSEGGSSSTMYVSGPPGPPGPPGP--PGSISSSGQEIQQYISEYMQSDSIRSYL 1031 G + G + G PGPPG PG PG + G Sbjct: 1203 PGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGP------------------- 1243 Query: 1032 SGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVL 1091 G +G PG PGPPGP SHV+ G Sbjct: 1244 PGSRGSPGAPGPPGPP-------------GSHVIGIKGDKG------------------- 1271 Query: 1092 QRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPP 1151 MG GP GPPG +GD M G +G PG P Sbjct: 1272 ------------SMGHPGPKGPPGTAGD------------------MGPPG-RLGAPGTP 1300 Query: 1152 GPPGLPGTSYEELLSLLRGSE----FRGIVGPPGPPGPPGIPG-----NVWSSISVEDLS 1202 G PG G + ++G + F G +GPPGP GP G PG IS+ Sbjct: 1301 GLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSP 1360 Query: 1203 SYLHTAGLSFIPGPPGPPGPP------GPRGPPGVSGALATYAAENSDSFRSELISYLTS 1256 T G + G PGPPGPP GPRG PG G T + Sbjct: 1361 GPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGS------- 1413 Query: 1257 PDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVR----RGSSYSSSMS 1312 G PGP G G PG RG S S + + R S ++++ Sbjct: 1414 -------KGEPGPAGSDGLPG--------LKGKRGDSGSPATWTTRGFVFTRHSQTTAIP 1458 Query: 1313 TGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGG 1345 + G L +G +F G++ +G D+G G Sbjct: 1459 SCPEGTVPLYSGFSFLFVQGNQRAHGQDLGTLG 1491 Score = 379 bits (974), Expect = e-105 Identities = 272/739 (36%), Positives = 316/739 (42%), Gaps = 195/739 (26%) Query: 566 RGSPGPKGDMGSPGPKGDR-GFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 RG GPKGD G PG DR GFPG G PG GH G GP GQ+G G+PG+ GP G+ G Sbjct: 832 RGKTGPKGDPGIPGL--DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889 Query: 625 REGPMGPRGEAGPPGS----GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQ---- 676 G MG G GPPG G G+RG+ G PG G G PG+ G +G G+PGP Sbjct: 890 VIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949 Query: 677 --GPPGPVGLQGL---------RGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPG 725 G G GL+G RG G+PG+KG KG GP GP G +G+ G G GEPG Sbjct: 950 VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009 Query: 726 MRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRG--------------PPGP 771 +RG+PG++G G G+ G G G G G GL G+ G++G PPGP Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP 1069 Query: 772 SGDPG---------------KPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSM 816 +GDPG PG GP GP+G PG+PG PG+ G+PG G + Sbjct: 1070 TGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL------GF 1123 Query: 817 LTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPG----------PPGPRG 866 + G GPPG GPPG PG PG GP G+ G Q + GP G PPGPRG Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRG 1183 Query: 867 PPGPSIPGPPGPRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGP-----KGDQ 920 PG G G RG PG GLPG G G T + G PGPPG PG G++ Sbjct: 1184 NPGAQ--GAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNR 1241 Query: 921 GPPGPRGHQGEQGLPGFSTSGSSSFGLNL-QGPPGPPGPQGPKGDKGDPGVPGALGIPSG 979 GPPG RG G G PG GS G+ +G G PGP+GP G GD G PG LG P Sbjct: 1242 GPPGSRGSPGAPGPPG--PPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGT 1299 Query: 980 PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPG 1039 P G G PG G G PG + S G G +GPPG Sbjct: 1300 PGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGP----------------IGPKGPPG 1343 Query: 1040 PPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQY 1099 G PG + I+ Sbjct: 1344 VRGDPGTLKIIS------------------------------------------------ 1355 Query: 1100 LRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGT 1159 L G GPPG PG G G PGPPGPPG G Sbjct: 1356 ----LPGSPGPPGTPGEPG-------------------------MQGEPGPPGPPGNLGP 1386 Query: 1160 SYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGP 1219 RG G G PG PGP G GN G PGP G Sbjct: 1387 CGP------RGKP--GKDGKPGTPGPAGEKGN----------------KGSKGEPGPAGS 1422 Query: 1220 PGPPGPRGPPGVSGALATY 1238 G PG +G G SG+ AT+ Sbjct: 1423 DGLPGLKGKRGDSGSPATW 1441 Score = 337 bits (865), Expect = 4e-92 Identities = 234/601 (38%), Positives = 268/601 (44%), Gaps = 136/601 (22%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 L GS G +G G PG G G PGTPG GP G G G G KG G PG+ G +G G Sbjct: 86 LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145 Query: 625 REGPMGPRGEAGPPGSGE------KGERGAAGEPGPH---GPPGVPGSVGPKGSS---GS 672 G G +G+ G P E KG+ G G PGP GPPG PG VGP G G Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205 Query: 673 PGPQGPPGPV--------------GLQGLRGEVGLPGV-----------------KGDKG 701 PG GP GP G++GL G G PG KGDKG Sbjct: 206 PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265 Query: 702 PMGPPGPKG-----------DQGEKGPRGLTGEPGM---------------RGLPGAVGE 735 MG PGP G ++G G GL G+PG RG PG +GE Sbjct: 266 AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325 Query: 736 PGAKGAMGPAGPDGHQGP---------RGEQGLTGMP---GIRGPPGPSGDPGKPGLTGP 783 G KG G GP G +GP +G++G G P G RGP GPSG PG PG G Sbjct: 326 DGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385 Query: 784 QGP--QGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPG----A 837 P +G PG PG G KGE G PGK S G PG PG+ GPPGPPG Sbjct: 386 SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSP-GCAGSPGLPGSPGPPGPPGDIVFR 444 Query: 838 PGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG------PSIPGPPGPRGPPG----EGLP 887 GP G GLPG+ L G PG GP+G PG P IPGPPG G PG +G+P Sbjct: 445 KGPPGDHGLPGY---LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP 501 Query: 888 GPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGH----QGEQGLPGFSTSGSS 943 G G G S +G PG PG PG +GD G G +G +G+ G+PG Sbjct: 502 GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQ 561 Query: 944 SFGLNLQGPPGPP------------------GPQGPKGDKGDPGVPGALGIPSGPSEGGS 985 L G PG P G QGP GD G PG PG G P+GP G Sbjct: 562 PGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAG-PAGPPGYGP 620 Query: 986 SSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPG 1045 + G G PG PGPPG G+ S+ + + G GPPGPPG PG Sbjct: 621 QGEPGLQGTQGVPGAPGPPGEAGPRGEL------------SVSTPVPGPPGPPGPPGHPG 668 Query: 1046 P 1046 P Sbjct: 669 P 669 Score = 329 bits (843), Expect = 1e-89 Identities = 307/896 (34%), Positives = 360/896 (40%), Gaps = 162/896 (18%) Query: 692 GLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQ 751 G G KG+KG GPPG G +G GP GL G G +G PG G G+KG G +G G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 752 GPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGI------KGEPGAP 805 G GL G PG GP G G PG G G QG GLPGT G PGI KG+ GAP Sbjct: 103 G---SPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAP 159 Query: 806 GKIVTSEGSSMLTVPGPPGPPGAMGP---PGPPGAPGPAGPAGLPGHQEVLNLQGPPGPP 862 K E L G PG PGA GP PGPPG PGP GP G PG G GP Sbjct: 160 AK----EEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPG---FFGFPGAMGPR 212 Query: 863 GPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFL--------------SNSETFLSGPP 908 GP+G G + G G RG +GL GPPGPPG+ + + G P Sbjct: 213 GPKGHMGERVIGHKGERGV--KGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEP 270 Query: 909 GPPGPPG--------PKGDQGPPGPRGHQGEQGLPGFSTS----GSSSF-GL-------N 948 GPPGP G KG G PG +G G+ G+PGF S G+ F GL Sbjct: 271 GPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKG 330 Query: 949 LQGPPGPPGPQGP---------KGDKGDPGVPGALGI-----PSGPSEGGSSSTMYVSGP 994 +G GPPG +GP KGD+G PG PG G PSGP S G Sbjct: 331 QKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGL 390 Query: 995 PGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGET 1054 G PG PG GS G+ + + S G+ G PGPPGPPG + G Sbjct: 391 RGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGS--PGLPGSPGPPGPPGDIVFRKGPP 448 Query: 1055 FDYSELASHVVSYLRTSGY-GVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGP 1113 D+ + YL + G GV E L Q Y+ GP G PG Sbjct: 449 GDHG-----LPGYLGSPGIPGV----DGPKGEPGLLCTQ--------CPYIPGPPGLPGL 491 Query: 1114 PGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSL------ 1167 PG G + A ++G+ G PG PG G PG E+ +L Sbjct: 492 PGLHGVKGIPGRQGAAGLKGSPGSPGNTGLP-GFPGFPGAQGDPGLKGEKGETLQPEGQV 550 Query: 1168 -------LRGSEFR-GIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGP 1219 LRG R G+ G PG PG G+PG LS G PG PG Sbjct: 551 GVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELA----LSGEKGDQGPPGDPGSPGS 606 Query: 1220 PGPPGPRGPP-----------GVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPG 1268 PGP GP GPP G G R EL V + + GPPG Sbjct: 607 PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGEL-------SVSTPVPGPPG 659 Query: 1269 PPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGG--------GGAGS 1320 PPGP G PG S + G G G GS Sbjct: 660 PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719 Query: 1321 LGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRV 1380 LG G GE G G G G G A GG G G G + ++ E+ + Sbjct: 720 LGCPGKMGE-PGLPGKPGLP-GAKGEPAVAMPGG--PGTPGFPG-ERGNSGEHGEIGLPG 774 Query: 1381 SESMQRQGLLQGMAYTVQGPPGQPGP---QGPPG--ISKVFSAYSNVTADLMDFFQTYGA 1435 + +G+ +G PGQPGP QGPPG I A Q Sbjct: 775 LPGLPGTPGNEGLD-GPRGDPGQPGPPGEQGPPGRCIEGPRGA------------QGLPG 821 Query: 1436 IQGPPGQKGEMGTPGPKGDRG-----PAGPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 + G GQ+G G GPKGD G +G PG G PG GH+GE G G + Y G Sbjct: 822 LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPG 877 Score = 310 bits (795), Expect = 5e-84 Identities = 186/424 (43%), Positives = 219/424 (51%), Gaps = 47/424 (11%) Query: 563 GNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGP--- 619 G G PGP GD G PG G +G G PG PG LG GP+G G GS G PG GP Sbjct: 1061 GTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGD 1120 Query: 620 MGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSG----SPG 674 +G +G +G +GP G GPPG G G G G G G G+PG G KG +G PG Sbjct: 1121 LGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPG 1180 Query: 675 PQGPPGPVGLQGLRGEVGLPGVKGDKGPM---GPPGPKGDQGEKGPRGLTGE--PGMRGL 729 P+G PG G +G RG G PG+ G KG M GP GP G +G GP GL G PG G Sbjct: 1181 PRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGN 1240 Query: 730 PGAVGEPGAKGAMGPAGPDGHQ--GPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQ 787 G G G+ GA GP GP G G +G++G G PG +GPPG +GD G PG G G Sbjct: 1241 RGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTP 1300 Query: 788 GLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLP 847 GLPG G PG +G PG G+ G PG G++GPPGP G GP G G P Sbjct: 1301 GLPGPRGDPGFQGFPGVKGE------------KGNPGFLGSIGPPGPIGPKGPPGVRGDP 1348 Query: 848 GHQEVLNLQGPPGPPGPRGPPG----PSIPGPP------GPRGPPG-EGLPGPPGPPGSF 896 G ++++L G PGPPG G PG P PGPP GPRG PG +G PG PGP G Sbjct: 1349 GTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGE- 1407 Query: 897 LSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPP 956 G G G PGP G G PG +G +G+ G P T+ F + Q P Sbjct: 1408 --------KGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPS 1459 Query: 957 GPQG 960 P+G Sbjct: 1460 CPEG 1463 Score = 303 bits (777), Expect = 6e-82 Identities = 284/868 (32%), Positives = 335/868 (38%), Gaps = 232/868 (26%) Query: 705 PPGPKG----DQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLT 760 P KG D+G+ G GE G +G PG G PG KG GP G G QGP+G GL Sbjct: 25 PAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLP 84 Query: 761 GMPG------IRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGS 814 G+ G I G PG SG PG PG G GP GL G PG G KGE G PG Sbjct: 85 GLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGL------- 137 Query: 815 SMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNL--QGPPGPPGPRGPPGPSI 872 PG +G PG PGA G G G P +E + L +G PG PG GP G + Sbjct: 138 -----------PGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQG--L 184 Query: 873 PGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQ 932 PGPPG GP G PPGPPG F G PG GP GPKG G GH+GE+ Sbjct: 185 PGPPGFPGPVG-----PPGPPGFF---------GFPGAMGPRGPKGHMGER-VIGHKGER 229 Query: 933 GLPGFSTSGSSSFGLNLQGPPGPPGP--------------QGPKGDKG---DPGVPGALG 975 G+ G L GPPGPPG +G KGDKG +PG PG G Sbjct: 230 GVKG------------LTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSG 277 Query: 976 IPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQ 1035 +P G S G G G PG G PG S G + + M D I+ G + Sbjct: 278 LP-GESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIK----GQK 332 Query: 1036 GPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDD 1095 G GPPG GP E +D +Y G + Sbjct: 333 GDIGPPGFRGPT-----EYYD---------TYQEKGDEGTPGPPGPRGAR---------- 368 Query: 1096 VRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPG 1155 GP+GP GPPG G SSR GL G PG PG Sbjct: 369 ----------GPQGPSGPPGVPGSPG---------SSRP-----------GLRGAPGWPG 398 Query: 1156 LPGTSYE------ELLSLLRGSEFRGIVGPPGPPGPPGIPGNVW---SSISVEDLSSYLH 1206 L G+ E + + G G PG PGPPG PG++ L YL Sbjct: 399 LKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLG 458 Query: 1207 TAGLS-----------------FIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSE 1249 + G+ +IPGPPG PG PG G G+ G + S Sbjct: 459 SPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPG---- 514 Query: 1250 LISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSS 1309 SP + + G PG PG QG PG + + G +R G Sbjct: 515 ------SPG-NTGLPGFPGFPGAQGDPG-LKGEKGETLQPEGQVGVPGDPGLR-GQPGRK 565 Query: 1310 SMSTGGGGAGSLGAGGAFGEAA-----GDRGPYGTDIGPGG----------GYGAAAEGG 1354 + G G G G GE A GD+GP G PG GYG E G Sbjct: 566 GLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625 Query: 1355 MYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISK 1414 + G G+ GA E+ R L ++ V GPPG PGP G PG Sbjct: 626 LQ-GTQGVPGAPGPP-----------GEAGPRGEL--SVSTPVPGPPGPPGPPGHPGP-- 669 Query: 1415 VFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPG-----HPGPPGP 1469 QGPPG G +G G G GP G PG PGPPGP Sbjct: 670 ----------------------QGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 707 Query: 1470 RGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 +G +G G KG G+ + KP Sbjct: 708 KGDQGFPGTKGSLGCPGKMGEPGLPGKP 735 Score = 236 bits (601), Expect = 2e-61 Identities = 127/273 (46%), Positives = 154/273 (56%), Gaps = 23/273 (8%) Query: 561 ENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPG---PLGHPGPQGPKGQKGSVGDPGME 617 E G LR PGP+G+ G+ G KGDRG PG PG+PG +G GP+GP G +G G PG+ Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230 Query: 618 GPM--GQRGREGPMGPRGEAG------PPGS---GEKGERGAAGEPGPHGPPGVPGSVGP 666 G + GQ G GP G RG G PPGS G KG++G+ G PGP GPPG G +GP Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290 Query: 667 ------KGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRG- 719 G+ G PGP+G PG G G++GE G PG G GP GP GPKG G +G G Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGT 1350 Query: 720 --LTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGK 777 + PG G PG GEPG +G GP GP G+ GP G +G G G G PGP+G+ G Sbjct: 1351 LKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGN 1410 Query: 778 PGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVT 810 G G GP G G PG G +G+ G+P T Sbjct: 1411 KGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTT 1443 Score = 113 bits (282), Expect = 2e-24 Identities = 60/121 (49%), Positives = 70/121 (57%), Gaps = 8/121 (6%) Query: 559 EQENGNLRGSPGPKGDMGSPGPKGDRGFPGT------PGIPGPLGHPGPQGPKGQKGSVG 612 E+ N GS GP G +G GP G RG PGT PG PGP G PG G +G+ G G Sbjct: 1320 EKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPG 1379 Query: 613 DPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGS 672 PG GP G RG+ G G G GP +GEKG +G+ GEPGP G G+PG G +G SGS Sbjct: 1380 PPGNLGPCGPRGKPGKDGKPGTPGP--AGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGS 1437 Query: 673 P 673 P Sbjct: 1438 P 1438 >gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo sapiens] Length = 1670 Score = 453 bits (1165), Expect = e-127 Identities = 385/1131 (34%), Positives = 454/1131 (40%), Gaps = 264/1131 (23%) Query: 560 QENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPL--------GHPGPQGPKGQKG-- 609 QE G+ G+PGP G G+ GP+G G PG PG PG G PG +G KG++G Sbjct: 351 QEKGD-EGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRP 409 Query: 610 ------SVGDPGMEGPMGQRGREGPMGPRGEA----GPPGS----------GEKGERGAA 649 + G PG G G G GP GP G+ GPPG G G G Sbjct: 410 GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPK 469 Query: 650 GEPG------PH--GPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKG 701 GEPG P+ GPPG+PG G G G PG QG G G G G GLPG G G Sbjct: 470 GEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPG 529 Query: 702 PMGPPGPKGDQGEK----------GPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQ 751 G PG KG++GE G GL G+PG +GL G G PG KG GP G Sbjct: 530 AQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALS 589 Query: 752 GPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTS 811 G +G+QG G PG G PGP+G G PG GPQG GL GT G PG G PG G Sbjct: 590 GEKGDQGPPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVPGAPGPPGEAGP--RG 646 Query: 812 EGSSMLTVPGPPGPPGAMGPPGP--------------------------------PGAPG 839 E S VPGPPGPPG G PGP PG PG Sbjct: 647 ELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPG 706 Query: 840 PAGPAGLPGHQEVLN---------LQGPPGPPGPRGPPGPSIPGPPGPRGPPGE------ 884 P G G PG + L L G PG PG +G P ++PG PG G PGE Sbjct: 707 PKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGE 766 Query: 885 ----GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPG-----PRGHQG----- 930 GLPG PG PG+ L GP G PG PGP G+QGPPG PRG QG Sbjct: 767 HGEIGLPGLPGLPGT---PGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLN 823 Query: 931 ----------------EQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGAL 974 + G+PG SG G PG G GP G +G PG PG L Sbjct: 824 GLKGQQGRRGKTGPKGDPGIPGLDRSGFPG-ETGSPGIPGHQGEMGPLGQRGYPGNPGIL 882 Query: 975 GIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSG----------------------- 1011 G P G GPPGPPG PG PG S G Sbjct: 883 GPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNP 942 Query: 1012 --QEIQQYISEYMQSDSIRSY-----------------LSGVQGPPGPPGPPGPVTTITG 1052 EI I + + ++ + L G++G PGP GPPGP + G Sbjct: 943 GPSEISHVIGDKGEP-GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL-G 1000 Query: 1053 ETFDYSELASH-VVSYLRTSGY-------GVSLFSSSISSEDILAV--LQRDDVRQ-YLR 1101 T + E + + G G F + + LQ D Y Sbjct: 1001 STGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSE 1060 Query: 1102 QYLMGPRGPPGPPGASGDGSLLSLDYAELSSR-ILSYMSSSGISIGLPGPPGPPGLPGTS 1160 GP GP G PG GD E+ ++ +G G PG PG PGLPG Sbjct: 1061 GTRPGPPGPTGDPGLPGDMG----KKGEMGQPGPPGHLGPAGPE-GAPGSPGSPGLPGKP 1115 Query: 1161 YEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPP 1220 +G +G++GPPG GPPG+PG S + G IPGP G Sbjct: 1116 GPHGDLGFKG--IKGLLGPPGIRGPPGLPGFPGSPGPM----GIRGDQGRDGIPGPAGEK 1169 Query: 1221 G-------PPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQ 1273 G PPGPRG PG GA A R +G GP GP Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPG-----------RKGAMGDAGPRGPT 1218 Query: 1274 G------PPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAF 1327 G PPG + + +RG S RGS + G G+ +G G Sbjct: 1219 GIEGFPGPPGLPGAIIPGQTGNRGPPGS-------RGSPGAPG-PPGPPGSHVIGIKGDK 1270 Query: 1328 GEAA--GDRGPYGT--DIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSES 1383 G G +GP GT D+GP G GA G+ G F G V Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG----------VKGE 1320 Query: 1384 MQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYG--AIQGPPG 1441 G L + GPPG GP+GPPG+ T ++ + G G PG Sbjct: 1321 KGNPGFLGSI-----GPPGPIGPKGPPGVRG-----DPGTLKIISLPGSPGPPGTPGEPG 1370 Query: 1442 QKGEMGTPGPKGDRGPAGP------PGHPGPPGPRGHKGEKGDKGDQVYAG 1486 +GE G PGP G+ GP GP G PG PGP G KG KG KG+ AG Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAG 1421 Score = 449 bits (1156), Expect = e-126 Identities = 354/1008 (35%), Positives = 421/1008 (41%), Gaps = 185/1008 (18%) Query: 563 GNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHP---GPQGPKGQKGSVGDPGME-- 617 G+ +G+PG G G PG G GFPG+ G+ G G P G G KGQKG +G PG Sbjct: 284 GSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGP 343 Query: 618 -------------------GPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPG----- 653 GP G RG +GP GP G G PGS G RGA G PG Sbjct: 344 TEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSK 403 Query: 654 ---------PHGPPGVPGSVGPKGSSGSPGPQGPP-------GPVGLQGLRGEVGLPGVK 697 G PG PG G G GSPGP GPP GP G GL G +G PG+ Sbjct: 404 GERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIP 463 Query: 698 GDKGPMGPPGPKGDQ-----GEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQG 752 G GP G PG Q G G GL G G++G+PG G G KG+ G G G G Sbjct: 464 GVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPG 523 Query: 753 PRGEQGLTGMPGIRG-------PPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAP 805 G G G PG++G P G G PG PGL G G +GL G PG PG+KG PG Sbjct: 524 FPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPK 583 Query: 806 GKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPR 865 G++ S PG PG PG+ GP GP G PG GP G PG Q + G PGPPG Sbjct: 584 GELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGTQGVPGAPGPPGEA 642 Query: 866 GPPG-----PSIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGD 919 GP G +PGPPGP GPPG G GPPG PGS + L GP G PG PG G Sbjct: 643 GPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG-IGF 701 Query: 920 QGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGV--PGALGIP 977 GPPGP+ G+QG PG T GS G PG PG G G KG+P V PG G P Sbjct: 702 PGPPGPK---GDQGFPG--TKGSLGCP-GKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTP 755 Query: 978 SGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGP 1037 P E G+S G PG PG PG PG+ G G G Sbjct: 756 GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR-------------------GDPGQ 796 Query: 1038 PGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVR 1097 PGPPG GP G + A + G Sbjct: 797 PGPPGEQGP----PGRCIEGPRGAQGLPGLNGLKG------------------------- 827 Query: 1098 QYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLP 1157 Q R+ GP+G PG PG G S I + G +G G PG PG+ Sbjct: 828 QQGRRGKTGPKGDPGIPGLDRSG----FPGETGSPGIPGHQGEMG-PLGQRGYPGNPGIL 882 Query: 1158 GTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPP 1217 G E+ + + G F G +GPPGPPG PG PG S + + T G G Sbjct: 883 GPPGEDGVIGMMG--FPGAIGPPGPPGNPGTPGQ-RGSPGIPGVKGQRGTPGAKGEQGDK 939 Query: 1218 GPPGPP------GPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPG 1271 G PGP G +G PG+ G + + P ++ + G PGP G Sbjct: 940 GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG-------MPGLKG-LKGLPGPAG 991 Query: 1272 PQGPPGDSRLLSTDASHSRGSSSSSHSSSVR--RGSSYSSSMSTGGGGAGSLGAGGAFGE 1329 P GP GD GS+ + +R GS + M G G+LG G G Sbjct: 992 PPGPRGD-----------LGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR 1040 Query: 1330 AA--GDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQ 1387 G G G PG G G+ GL GD+ M + Sbjct: 1041 PGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL-----PGDMG-------KKGEMGQP 1088 Query: 1388 GLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMG 1447 G + GP G PG G PG+ + ++ + I+GPPG G G Sbjct: 1089 GPPGHLG--PAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPG 1146 Query: 1448 TPGPKGDRGPAGPPGHPG-------------PPGPRGHKGEKGDKGDQ 1482 +PGP G RG G G PG PPGPRG+ G +G KGD+ Sbjct: 1147 SPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDR 1194 Score = 442 bits (1137), Expect = e-123 Identities = 357/1038 (34%), Positives = 431/1038 (41%), Gaps = 205/1038 (19%) Query: 572 KGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQR--GREGPM 629 KGD G PG G +G PG PG PGP+G PGP G G G++G G +G MG+R G +G Sbjct: 170 KGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGER 229 Query: 630 GPRGEAGPPG------------------SGEKGERGAAGEPGPHGPPGVPGSV--GPKGS 669 G +G GPPG GEKG++GA GEPGP GP G+PG KG+ Sbjct: 230 GVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGA 289 Query: 670 SGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTG------- 722 G PG QG PG G+ G G G+ G +G G MG G KG +G+ GP G G Sbjct: 290 PGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDT 349 Query: 723 --EPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGE-----QGLTGMPGIRGPPGPSGDP 775 E G G PG G GA+G GP+GP G G G +G G PG++G G G P Sbjct: 350 YQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRP 409 Query: 776 GKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGS-------------SMLTVPGP 822 GK + P P G G+PG PG G PG PG IV +G + V GP Sbjct: 410 GKDAMGTPGSP-GCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGP 468 Query: 823 PGPPGAM--------GPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG----- 869 G PG + GPPG PG PG G G+PG Q L+G PG PG G PG Sbjct: 469 KGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFP 528 Query: 870 ---------------------PSIPGPPGPRGPPG----EGLPGPPG------PPGSFLS 898 +PG PG RG PG +G+PG PG P G Sbjct: 529 GAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELAL 588 Query: 899 NSETFLSGPPGPPGPPGPKGDQGPPGPRGH--------QGEQGLPGF-------STSGSS 943 + E GPPG PG PG G GP GP G+ QG QG+PG G Sbjct: 589 SGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGEL 648 Query: 944 SFGLNLQGPPGPPGPQGPKGDKGDPGVPGALG------IPSGPSEGGSSSTMYVSGPPGP 997 S + GPPGPPGP G G +G PG+PG+LG +P E G + GPPGP Sbjct: 649 SVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF-PGPPGP 707 Query: 998 PGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDY 1057 G G PG+ S G G G PG PG PG + G Sbjct: 708 KGDQGFPGTKGSLG-------------------CPGKMGEPGLPGKPG----LPGAK--- 741 Query: 1058 SELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGAS 1117 E A + T G+ +S E L L + L GPRG PG PG Sbjct: 742 GEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPG-NEGLDGPRGDPGQPGPP 800 Query: 1118 GDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIV 1177 G+ G I GP G GLPG L+ L+G + G Sbjct: 801 GE------------------QGPPGRCI--EGPRGAQGLPG------LNGLKGQQ--GRR 832 Query: 1178 GPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALAT 1237 G GP G PGIPG D S + G IPG G GP G RG PG G L Sbjct: 833 GKTGPKGDPGIPG--------LDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884 Query: 1238 YAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSH 1297 + +I + P +GPPGPPG G PG + + + Sbjct: 885 PGEDG-------VIGMMGFPGA----IGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAK 933 Query: 1298 SSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPG--GGYGAAAEGGM 1355 +G+ S +S G G G G F G++G G PG G G G Sbjct: 934 GEQGDKGNPGPSEISHVIGDKGEPGLKG-FAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992 Query: 1356 YAGNGGLLGADFAGDLDYNELAVRVSESMQRQGL--LQGMAYTVQGPPGQPGPQGPPGI- 1412 G L G+ + SM G+ +G T+ G PG+ G G PGI Sbjct: 993 PGPRGDLGSTGNPGEPGLR----GIPGSMGNMGMPGSKGKRGTL-GFPGRAGRPGLPGIH 1047 Query: 1413 ----SKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPG 1468 K YS T + G G+KGEMG PGP G GPAGP G PG PG Sbjct: 1048 GLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPG 1107 Query: 1469 PRGHKGEKGDKGDQVYAG 1486 G G+ G GD + G Sbjct: 1108 SPGLPGKPGPHGDLGFKG 1125 Score = 419 bits (1076), Expect = e-116 Identities = 349/1025 (34%), Positives = 410/1025 (40%), Gaps = 238/1025 (23%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGH------PGPQGPKGQKGSVGDPGMEGP 619 +G G KG G PG G +GF G G+PGP G PG G KG +G G PG G Sbjct: 45 KGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGS 104 Query: 620 MGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSP----- 673 G G G GP G G PG SG KGE+G G PG G PG+PG+ G KG G+P Sbjct: 105 PGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164 Query: 674 ---------------GPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGE---- 714 GPQG PGP G G G G PG G G MGP GPKG GE Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIG 224 Query: 715 -KGPRGLTGEPGMRGLPGAV--------------GEPGAKGAMGPAGPDGHQGPRGE--- 756 KG RG+ G G G PG V GE G KGAMG GP G G GE Sbjct: 225 HKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYG 284 Query: 757 --QGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGS 814 +G G PG++G PG G PG PG G +G +G PG G GIKG+ G G + Sbjct: 285 SEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPT 344 Query: 815 SMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGP--PGPRGPPG-PS 871 G G GPPGP GA GP GP+G PG + G PG PG RG PG P Sbjct: 345 EYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPG------VPGSPGSSRPGLRGAPGWPG 398 Query: 872 IPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGD----QGPPGPRG 927 + G G RG PG+ G PG PG S G PG PGPPGP GD +GPPG G Sbjct: 399 LKGSKGERGRPGKDAMGTPGSPGCAGS------PGLPGSPGPPGPPGDIVFRKGPPGDHG 452 Query: 928 ---HQGEQGLPGFSTSGSSSFGLNLQ-----GPPGPPGPQGPKGDKGDPGVPGALGIPSG 979 + G G+PG L Q GPPG PG G G KG PG GA G+ Sbjct: 453 LPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGS 512 Query: 980 PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSI------RSYLSG 1033 P G++ + G PG PG G PG G+ +Q + D R L G Sbjct: 513 PGSPGNTG---LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDG 569 Query: 1034 VQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQR 1093 + G PG G PGP ELA +S E Sbjct: 570 IPGTPGVKGLPGPK----------GELA--------------------LSGEK------- 592 Query: 1094 DDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGP 1153 G +GPPG PG+ G PGP GP Sbjct: 593 ------------GDQGPPGDPGSPGS----------------------------PGPAGP 612 Query: 1154 PGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFI 1213 G PG + L +G++ G+ G PGPPG G G + S V Sbjct: 613 AGPPGYGPQGEPGL-QGTQ--GVPGAPGPPGEAGPRGELSVSTPVPGP------------ 657 Query: 1214 PGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVG-----PPG 1268 PGPPGPPG PGP+GPPG+ G+L L PD I G PPG Sbjct: 658 PGPPGPPGHPGPQGPPGIPGSLGKCGDPG-----------LPGPDGEPGIPGIGFPGPPG 706 Query: 1269 PPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFG 1328 P G QG PG L +G + +M G G G G G G Sbjct: 707 PKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEP-AVAMPGGPGTPGFPGERGNSG 765 Query: 1329 EAA-----------GDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELA 1377 E G G G D GP G G G G + Sbjct: 766 EHGEIGLPGLPGLPGTPGNEGLD-GPRGDPGQPGPPGEQGPPGRCIEGP----------- 813 Query: 1378 VRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVF-SAYSNVTADL---------- 1426 R ++ + L+G QG G+ GP+G PGI + S + T Sbjct: 814 -RGAQGLPGLNGLKGQ----QGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMG 868 Query: 1427 ---MDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQV 1483 + I GPPG+ G +G G G GP GPPG+PG PG RG G G KG + Sbjct: 869 PLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRG 928 Query: 1484 YAGRR 1488 G + Sbjct: 929 TPGAK 933 Score = 418 bits (1075), Expect = e-116 Identities = 349/1036 (33%), Positives = 415/1036 (40%), Gaps = 262/1036 (25%) Query: 560 QENGNLRGSPG----PKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQG---PKGQKGSVG 612 Q + L+G G P+G +G PG G RG PG G+ G G PG +G PKG+ G Sbjct: 531 QGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSG 590 Query: 613 DPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGE---RGAAGEPGPHGPPG---------- 659 + G +GP G G G GP G AGPPG G +GE +G G PG GPPG Sbjct: 591 EKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV 650 Query: 660 ---VPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGP-----MGPPGPKGD 711 VPG GP G G PGPQGPPG G G G+ GLPG G+ G GPPGPKGD Sbjct: 651 STPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGD 710 Query: 712 QGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMG------PAGPD--------GHQGPRGEQ 757 QG G +G G PG G PG G+PG GA G P GP G+ G GE Sbjct: 711 QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770 Query: 758 GLTGMPGIRGPP------GPSGDPGKPG-----------LTGPQGPQGLP---------G 791 GL G+PG+ G P GP GDPG+PG + GP+G QGLP G Sbjct: 771 GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830 Query: 792 TPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQE 851 G+ G KG+PG PG + S PG PG G MGP G G PG G G PG Sbjct: 831 RRGKTGPKGDPGIPG-LDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889 Query: 852 VLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGP- 910 V+ + G PG GP GPPG PG PG RG P G+PG G G+ + E G PGP Sbjct: 890 VIGMMGFPGAIGPPGPPGN--PGTPGQRGSP--GIPGVKGQRGTPGAKGEQGDKGNPGPS 945 Query: 911 --------PGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGL-NLQGPPGPPGPQGP 961 G PG KG G PG +G++G G+PG GL L GP GPPGP+G Sbjct: 946 EISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLK-------GLKGLPGPAGPPGPRGD 998 Query: 962 KGDKGDPGVPGALGIPSG------PSEGGSSSTMYV------------------------ 991 G G+PG PG GIP P G T+ Sbjct: 999 LGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGY 1058 Query: 992 -----SGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGP 1046 GPPGP G PG PG + G+ Q ++ +G +G PG PG PG Sbjct: 1059 SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGP-------AGPEGAPGSPGSPG- 1110 Query: 1047 VTTITGETFDYSELA-SHVVSYLRTSGY----GVSLFSSSISSEDILAVLQRDDV----- 1096 + G+ + +L + L G G+ F S I RD + Sbjct: 1111 ---LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAG 1167 Query: 1097 ---RQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGP 1153 L + GPRG PG GA GD + G G+ G PGP Sbjct: 1168 EKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRG-PTGIEGFPGP 1226 Query: 1154 PGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPP-----GIPGNVWSSISVEDLSSYLHTA 1208 PGLPG RG G PGPPGPP GI G+ S+ TA Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK-GSMGHPGPKGPPGTA 1285 Query: 1209 GLSFIP---GPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVG 1265 G P G PG PG PGPRG PG G + + F +G Sbjct: 1286 GDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS--------------IG 1331 Query: 1266 PPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGG 1325 PPGP GP+GPPG RG G+ S+ G G+ G G Sbjct: 1332 PPGPIGPKGPPG-----------VRGDP----------GTLKIISLPGSPGPPGTPGEPG 1370 Query: 1326 AFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQ 1385 GE G GP G ++GP G G + Sbjct: 1371 MQGE-PGPPGPPG-NLGPCGPRGKPGK--------------------------------- 1395 Query: 1386 RQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGE 1445 G PG PGP G G +G PG G Sbjct: 1396 ------------DGKPGTPGPAGEKGNK---------------------GSKGEPGPAGS 1422 Query: 1446 MGTPGPKGDRGPAGPP 1461 G PG KG RG +G P Sbjct: 1423 DGLPGLKGKRGDSGSP 1438 Score = 413 bits (1062), Expect = e-115 Identities = 304/873 (34%), Positives = 367/873 (42%), Gaps = 228/873 (26%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGP------- 619 G+PG G+ G+ G G+ G PG PG+PG G+ G GP+G G G PG +GP Sbjct: 753 GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812 Query: 620 -------------MGQRGREGPMGPRGEAGPPG---------------------SGEKGE 645 GQ+GR G GP+G+ G PG G G+ Sbjct: 813 PRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ 872 Query: 646 RGAAGEPGPHGPP---------GVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGV 696 RG G PG GPP G PG++GP G G+PG G G G+ G++G+ G PG Sbjct: 873 RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932 Query: 697 KGDKGPMGPPGPK------GDQGEKGPRGLTGEP---GMRGLPGAVGEPGAKGAMGPAGP 747 KG++G G PGP GD+GE G +G G P G RG+PG G G KG GPAGP Sbjct: 933 KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992 Query: 748 DGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGK 807 G +G G G G PG+RG PG G+ G PG G +G G PG GRPG+ G G G Sbjct: 993 PGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGD 1052 Query: 808 IVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGP 867 G S T PGPPGP G G PG G G G G PGH GP GP G G Sbjct: 1053 -KGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGH------LGPAGPEGAPGS 1105 Query: 868 PG-PSIPGPPGPRGPPG----EGLPGPP---GPPGSFLSNSETFLSGPPGPPGPPGPKGD 919 PG P +PG PGP G G +GL GPP GPPG L G PG PGP G +GD Sbjct: 1106 PGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPG---------LPGFPGSPGPMGIRGD 1156 Query: 920 QGP---PGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGP---PGPQGPKGDKGDPGVPGA 973 QG PGP G +GE GL L+ PPGP PG QG KGD+G PG PG Sbjct: 1157 QGRDGIPGPAGEKGETGL--------------LRAPPGPRGNPGAQGAKGDRGAPGFPGL 1202 Query: 974 LGIPSGPSEGGSSSTMYVSGPPGPPGPPGP--PGSISSSGQEIQQYISEYMQSDSIRSYL 1031 G + G + G PGPPG PG PG + G Sbjct: 1203 PGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGP------------------- 1243 Query: 1032 SGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVL 1091 G +G PG PGPPGP SHV+ G Sbjct: 1244 PGSRGSPGAPGPPGPP-------------GSHVIGIKGDKG------------------- 1271 Query: 1092 QRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPP 1151 MG GP GPPG +GD M G +G PG P Sbjct: 1272 ------------SMGHPGPKGPPGTAGD------------------MGPPG-RLGAPGTP 1300 Query: 1152 GPPGLPGTSYEELLSLLRGSE----FRGIVGPPGPPGPPGIPG-----NVWSSISVEDLS 1202 G PG G + ++G + F G +GPPGP GP G PG IS+ Sbjct: 1301 GLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSP 1360 Query: 1203 SYLHTAGLSFIPGPPGPPGPP------GPRGPPGVSGALATYAAENSDSFRSELISYLTS 1256 T G + G PGPPGPP GPRG PG G T + Sbjct: 1361 GPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGS------- 1413 Query: 1257 PDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVR----RGSSYSSSMS 1312 G PGP G G PG RG S S + + R S ++++ Sbjct: 1414 -------KGEPGPAGSDGLPG--------LKGKRGDSGSPATWTTRGFVFTRHSQTTAIP 1458 Query: 1313 TGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGG 1345 + G L +G +F G++ +G D+G G Sbjct: 1459 SCPEGTVPLYSGFSFLFVQGNQRAHGQDLGTLG 1491 Score = 379 bits (974), Expect = e-105 Identities = 272/739 (36%), Positives = 316/739 (42%), Gaps = 195/739 (26%) Query: 566 RGSPGPKGDMGSPGPKGDR-GFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 RG GPKGD G PG DR GFPG G PG GH G GP GQ+G G+PG+ GP G+ G Sbjct: 832 RGKTGPKGDPGIPGL--DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889 Query: 625 REGPMGPRGEAGPPGS----GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQ---- 676 G MG G GPPG G G+RG+ G PG G G PG+ G +G G+PGP Sbjct: 890 VIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949 Query: 677 --GPPGPVGLQGL---------RGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPG 725 G G GL+G RG G+PG+KG KG GP GP G +G+ G G GEPG Sbjct: 950 VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009 Query: 726 MRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRG--------------PPGP 771 +RG+PG++G G G+ G G G G G GL G+ G++G PPGP Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP 1069 Query: 772 SGDPG---------------KPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSM 816 +GDPG PG GP GP+G PG+PG PG+ G+PG G + Sbjct: 1070 TGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL------GF 1123 Query: 817 LTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPG----------PPGPRG 866 + G GPPG GPPG PG PG GP G+ G Q + GP G PPGPRG Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRG 1183 Query: 867 PPGPSIPGPPGPRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGP-----KGDQ 920 PG G G RG PG GLPG G G T + G PGPPG PG G++ Sbjct: 1184 NPGAQ--GAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNR 1241 Query: 921 GPPGPRGHQGEQGLPGFSTSGSSSFGLNL-QGPPGPPGPQGPKGDKGDPGVPGALGIPSG 979 GPPG RG G G PG GS G+ +G G PGP+GP G GD G PG LG P Sbjct: 1242 GPPGSRGSPGAPGPPG--PPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGT 1299 Query: 980 PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPG 1039 P G G PG G G PG + S G G +GPPG Sbjct: 1300 PGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGP----------------IGPKGPPG 1343 Query: 1040 PPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQY 1099 G PG + I+ Sbjct: 1344 VRGDPGTLKIIS------------------------------------------------ 1355 Query: 1100 LRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGT 1159 L G GPPG PG G G PGPPGPPG G Sbjct: 1356 ----LPGSPGPPGTPGEPG-------------------------MQGEPGPPGPPGNLGP 1386 Query: 1160 SYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGP 1219 RG G G PG PGP G GN G PGP G Sbjct: 1387 CGP------RGKP--GKDGKPGTPGPAGEKGN----------------KGSKGEPGPAGS 1422 Query: 1220 PGPPGPRGPPGVSGALATY 1238 G PG +G G SG+ AT+ Sbjct: 1423 DGLPGLKGKRGDSGSPATW 1441 Score = 337 bits (865), Expect = 4e-92 Identities = 234/601 (38%), Positives = 268/601 (44%), Gaps = 136/601 (22%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 L GS G +G G PG G G PGTPG GP G G G G KG G PG+ G +G G Sbjct: 86 LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145 Query: 625 REGPMGPRGEAGPPGSGE------KGERGAAGEPGPH---GPPGVPGSVGPKGSS---GS 672 G G +G+ G P E KG+ G G PGP GPPG PG VGP G G Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205 Query: 673 PGPQGPPGPV--------------GLQGLRGEVGLPGV-----------------KGDKG 701 PG GP GP G++GL G G PG KGDKG Sbjct: 206 PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265 Query: 702 PMGPPGPKG-----------DQGEKGPRGLTGEPGM---------------RGLPGAVGE 735 MG PGP G ++G G GL G+PG RG PG +GE Sbjct: 266 AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325 Query: 736 PGAKGAMGPAGPDGHQGP---------RGEQGLTGMP---GIRGPPGPSGDPGKPGLTGP 783 G KG G GP G +GP +G++G G P G RGP GPSG PG PG G Sbjct: 326 DGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385 Query: 784 QGP--QGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPG----A 837 P +G PG PG G KGE G PGK S G PG PG+ GPPGPPG Sbjct: 386 SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSP-GCAGSPGLPGSPGPPGPPGDIVFR 444 Query: 838 PGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG------PSIPGPPGPRGPPG----EGLP 887 GP G GLPG+ L G PG GP+G PG P IPGPPG G PG +G+P Sbjct: 445 KGPPGDHGLPGY---LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP 501 Query: 888 GPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGH----QGEQGLPGFSTSGSS 943 G G G S +G PG PG PG +GD G G +G +G+ G+PG Sbjct: 502 GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQ 561 Query: 944 SFGLNLQGPPGPP------------------GPQGPKGDKGDPGVPGALGIPSGPSEGGS 985 L G PG P G QGP GD G PG PG G P+GP G Sbjct: 562 PGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAG-PAGPPGYGP 620 Query: 986 SSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPG 1045 + G G PG PGPPG G+ S+ + + G GPPGPPG PG Sbjct: 621 QGEPGLQGTQGVPGAPGPPGEAGPRGEL------------SVSTPVPGPPGPPGPPGHPG 668 Query: 1046 P 1046 P Sbjct: 669 P 669 Score = 329 bits (843), Expect = 1e-89 Identities = 307/896 (34%), Positives = 360/896 (40%), Gaps = 162/896 (18%) Query: 692 GLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQ 751 G G KG+KG GPPG G +G GP GL G G +G PG G G+KG G +G G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 752 GPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGI------KGEPGAP 805 G GL G PG GP G G PG G G QG GLPGT G PGI KG+ GAP Sbjct: 103 G---SPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAP 159 Query: 806 GKIVTSEGSSMLTVPGPPGPPGAMGP---PGPPGAPGPAGPAGLPGHQEVLNLQGPPGPP 862 K E L G PG PGA GP PGPPG PGP GP G PG G GP Sbjct: 160 AK----EEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPG---FFGFPGAMGPR 212 Query: 863 GPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFL--------------SNSETFLSGPP 908 GP+G G + G G RG +GL GPPGPPG+ + + G P Sbjct: 213 GPKGHMGERVIGHKGERGV--KGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEP 270 Query: 909 GPPGPPG--------PKGDQGPPGPRGHQGEQGLPGFSTS----GSSSF-GL-------N 948 GPPGP G KG G PG +G G+ G+PGF S G+ F GL Sbjct: 271 GPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKG 330 Query: 949 LQGPPGPPGPQGP---------KGDKGDPGVPGALGI-----PSGPSEGGSSSTMYVSGP 994 +G GPPG +GP KGD+G PG PG G PSGP S G Sbjct: 331 QKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGL 390 Query: 995 PGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGET 1054 G PG PG GS G+ + + S G+ G PGPPGPPG + G Sbjct: 391 RGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGS--PGLPGSPGPPGPPGDIVFRKGPP 448 Query: 1055 FDYSELASHVVSYLRTSGY-GVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGP 1113 D+ + YL + G GV E L Q Y+ GP G PG Sbjct: 449 GDHG-----LPGYLGSPGIPGV----DGPKGEPGLLCTQ--------CPYIPGPPGLPGL 491 Query: 1114 PGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSL------ 1167 PG G + A ++G+ G PG PG G PG E+ +L Sbjct: 492 PGLHGVKGIPGRQGAAGLKGSPGSPGNTGLP-GFPGFPGAQGDPGLKGEKGETLQPEGQV 550 Query: 1168 -------LRGSEFR-GIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGP 1219 LRG R G+ G PG PG G+PG LS G PG PG Sbjct: 551 GVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELA----LSGEKGDQGPPGDPGSPGS 606 Query: 1220 PGPPGPRGPP-----------GVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPG 1268 PGP GP GPP G G R EL V + + GPPG Sbjct: 607 PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGEL-------SVSTPVPGPPG 659 Query: 1269 PPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGG--------GGAGS 1320 PPGP G PG S + G G G GS Sbjct: 660 PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719 Query: 1321 LGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRV 1380 LG G GE G G G G G A GG G G G + ++ E+ + Sbjct: 720 LGCPGKMGE-PGLPGKPGLP-GAKGEPAVAMPGG--PGTPGFPG-ERGNSGEHGEIGLPG 774 Query: 1381 SESMQRQGLLQGMAYTVQGPPGQPGP---QGPPG--ISKVFSAYSNVTADLMDFFQTYGA 1435 + +G+ +G PGQPGP QGPPG I A Q Sbjct: 775 LPGLPGTPGNEGLD-GPRGDPGQPGPPGEQGPPGRCIEGPRGA------------QGLPG 821 Query: 1436 IQGPPGQKGEMGTPGPKGDRG-----PAGPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 + G GQ+G G GPKGD G +G PG G PG GH+GE G G + Y G Sbjct: 822 LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPG 877 Score = 310 bits (795), Expect = 5e-84 Identities = 186/424 (43%), Positives = 219/424 (51%), Gaps = 47/424 (11%) Query: 563 GNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGP--- 619 G G PGP GD G PG G +G G PG PG LG GP+G G GS G PG GP Sbjct: 1061 GTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGD 1120 Query: 620 MGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSG----SPG 674 +G +G +G +GP G GPPG G G G G G G G+PG G KG +G PG Sbjct: 1121 LGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPG 1180 Query: 675 PQGPPGPVGLQGLRGEVGLPGVKGDKGPM---GPPGPKGDQGEKGPRGLTGE--PGMRGL 729 P+G PG G +G RG G PG+ G KG M GP GP G +G GP GL G PG G Sbjct: 1181 PRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGN 1240 Query: 730 PGAVGEPGAKGAMGPAGPDGHQ--GPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQ 787 G G G+ GA GP GP G G +G++G G PG +GPPG +GD G PG G G Sbjct: 1241 RGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTP 1300 Query: 788 GLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLP 847 GLPG G PG +G PG G+ G PG G++GPPGP G GP G G P Sbjct: 1301 GLPGPRGDPGFQGFPGVKGE------------KGNPGFLGSIGPPGPIGPKGPPGVRGDP 1348 Query: 848 GHQEVLNLQGPPGPPGPRGPPG----PSIPGPP------GPRGPPG-EGLPGPPGPPGSF 896 G ++++L G PGPPG G PG P PGPP GPRG PG +G PG PGP G Sbjct: 1349 GTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGE- 1407 Query: 897 LSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPP 956 G G G PGP G G PG +G +G+ G P T+ F + Q P Sbjct: 1408 --------KGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPS 1459 Query: 957 GPQG 960 P+G Sbjct: 1460 CPEG 1463 Score = 303 bits (777), Expect = 6e-82 Identities = 284/868 (32%), Positives = 335/868 (38%), Gaps = 232/868 (26%) Query: 705 PPGPKG----DQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLT 760 P KG D+G+ G GE G +G PG G PG KG GP G G QGP+G GL Sbjct: 25 PAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLP 84 Query: 761 GMPG------IRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGS 814 G+ G I G PG SG PG PG G GP GL G PG G KGE G PG Sbjct: 85 GLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGL------- 137 Query: 815 SMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNL--QGPPGPPGPRGPPGPSI 872 PG +G PG PGA G G G P +E + L +G PG PG GP G + Sbjct: 138 -----------PGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQG--L 184 Query: 873 PGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQ 932 PGPPG GP G PPGPPG F G PG GP GPKG G GH+GE+ Sbjct: 185 PGPPGFPGPVG-----PPGPPGFF---------GFPGAMGPRGPKGHMGER-VIGHKGER 229 Query: 933 GLPGFSTSGSSSFGLNLQGPPGPPGP--------------QGPKGDKG---DPGVPGALG 975 G+ G L GPPGPPG +G KGDKG +PG PG G Sbjct: 230 GVKG------------LTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSG 277 Query: 976 IPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQ 1035 +P G S G G G PG G PG S G + + M D I+ G + Sbjct: 278 LP-GESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIK----GQK 332 Query: 1036 GPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDD 1095 G GPPG GP E +D +Y G + Sbjct: 333 GDIGPPGFRGPT-----EYYD---------TYQEKGDEGTPGPPGPRGAR---------- 368 Query: 1096 VRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPG 1155 GP+GP GPPG G SSR GL G PG PG Sbjct: 369 ----------GPQGPSGPPGVPGSPG---------SSRP-----------GLRGAPGWPG 398 Query: 1156 LPGTSYE------ELLSLLRGSEFRGIVGPPGPPGPPGIPGNVW---SSISVEDLSSYLH 1206 L G+ E + + G G PG PGPPG PG++ L YL Sbjct: 399 LKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLG 458 Query: 1207 TAGLS-----------------FIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSE 1249 + G+ +IPGPPG PG PG G G+ G + S Sbjct: 459 SPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPG---- 514 Query: 1250 LISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSS 1309 SP + + G PG PG QG PG + + G +R G Sbjct: 515 ------SPG-NTGLPGFPGFPGAQGDPG-LKGEKGETLQPEGQVGVPGDPGLR-GQPGRK 565 Query: 1310 SMSTGGGGAGSLGAGGAFGEAA-----GDRGPYGTDIGPGG----------GYGAAAEGG 1354 + G G G G GE A GD+GP G PG GYG E G Sbjct: 566 GLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625 Query: 1355 MYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISK 1414 + G G+ GA E+ R L ++ V GPPG PGP G PG Sbjct: 626 LQ-GTQGVPGAPGPP-----------GEAGPRGEL--SVSTPVPGPPGPPGPPGHPGP-- 669 Query: 1415 VFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPG-----HPGPPGP 1469 QGPPG G +G G G GP G PG PGPPGP Sbjct: 670 ----------------------QGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 707 Query: 1470 RGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 +G +G G KG G+ + KP Sbjct: 708 KGDQGFPGTKGSLGCPGKMGEPGLPGKP 735 Score = 236 bits (601), Expect = 2e-61 Identities = 127/273 (46%), Positives = 154/273 (56%), Gaps = 23/273 (8%) Query: 561 ENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPG---PLGHPGPQGPKGQKGSVGDPGME 617 E G LR PGP+G+ G+ G KGDRG PG PG+PG +G GP+GP G +G G PG+ Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230 Query: 618 GPM--GQRGREGPMGPRGEAG------PPGS---GEKGERGAAGEPGPHGPPGVPGSVGP 666 G + GQ G GP G RG G PPGS G KG++G+ G PGP GPPG G +GP Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290 Query: 667 ------KGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRG- 719 G+ G PGP+G PG G G++GE G PG G GP GP GPKG G +G G Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGT 1350 Query: 720 --LTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGK 777 + PG G PG GEPG +G GP GP G+ GP G +G G G G PGP+G+ G Sbjct: 1351 LKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGN 1410 Query: 778 PGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVT 810 G G GP G G PG G +G+ G+P T Sbjct: 1411 KGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTT 1443 Score = 113 bits (282), Expect = 2e-24 Identities = 60/121 (49%), Positives = 70/121 (57%), Gaps = 8/121 (6%) Query: 559 EQENGNLRGSPGPKGDMGSPGPKGDRGFPGT------PGIPGPLGHPGPQGPKGQKGSVG 612 E+ N GS GP G +G GP G RG PGT PG PGP G PG G +G+ G G Sbjct: 1320 EKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPG 1379 Query: 613 DPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGS 672 PG GP G RG+ G G G GP +GEKG +G+ GEPGP G G+PG G +G SGS Sbjct: 1380 PPGNLGPCGPRGKPGKDGKPGTPGP--AGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGS 1437 Query: 673 P 673 P Sbjct: 1438 P 1438 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 452 bits (1162), Expect = e-126 Identities = 354/1030 (34%), Positives = 434/1030 (42%), Gaps = 203/1030 (19%) Query: 569 PGPKGDMGSPGPKGDRGFPGTPGI--------PGPLGHPGPQGPKGQKGSVGDPGMEGPM 620 PGP G G PGP G G PG PG PGP G GP G GQ G +G+ G +G Sbjct: 404 PGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQK 463 Query: 621 GQ----------RGREGPMGPRGEAGPPGS-GEKGERGAAGEPGPHGPPGVPGSVGPKGS 669 G+ RG GP GP GE G PG G KG+RG PG G GVPG G G Sbjct: 464 GESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGL---PGRDGVAGVPGPQGTPGL 520 Query: 670 SGSPGPQGPPGP----VGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPG 725 G PG +G PG + L+G +G+ G PG G G G PG G G GP+G G G Sbjct: 521 IGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVG 580 Query: 726 M---RGLPGAVGEPGAKGAMGPAGPDGH--QGPRGEQGLTGMPG---------------- 764 + RG PG VG PG++G GP GP G+ GP G++G G PG Sbjct: 581 LKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGK 640 Query: 765 ---IRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPG 821 + GPPG G PG PG GPQG +G PGTPGRPG+ GE GA G+ + PG Sbjct: 641 IVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQ-------PGIGFPG 693 Query: 822 PPGP------PGAMGPPGPPGAPG----PAGPA----------GLPGHQEVLNLQGPPGP 861 PPGP PG MGPPG PG PG P P GLPG + + L G PG Sbjct: 694 PPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGT 753 Query: 862 PGPRGPPG-PSIPGPPGPRGPPG----EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGP 916 PG +G G P +PG G GPPG G PGPPG PGS S + GPPG GPPG Sbjct: 754 PGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGI-GPPGARGPPGG 812 Query: 917 KGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGD---PGVPGA 973 +G G GP G +GE+G PGF GL++ GP G G QG G G PG+PG Sbjct: 813 QGPPGLSGPPGIKGEKGFPGFP-------GLDMPGPKGDKGAQGLPGITGQSGLPGLPGQ 865 Query: 974 LGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSY--L 1031 G P P GS M V G PG PG PGP G+ G++ + S R L Sbjct: 866 QGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDH---GFPGSSGPRGDPGL 922 Query: 1032 SGVQGPPGPPGPPGPVTTIT-----GETFDYSELASHVVSYLRTSGYGVSLFSSSISSED 1086 G +G G PG PG + + G+ D E + + G + + +D Sbjct: 923 KGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQ--IGPIGEKGSRGDPGTPGVPGKD 980 Query: 1087 ILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIG 1146 G G PG PG GD + S + + G Sbjct: 981 -------------------GQAGQPGQPGPKGDPGI----------------SGTPGAPG 1005 Query: 1147 LPGPPGPPG---LPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSS-------- 1195 LPGP G G LPGT E +G+ G PGP G PG+PG+ + Sbjct: 1006 LPGPKGSVGGMGLPGTPGE-----------KGVPGIPGPQGSPGLPGDKGAKGEKGQAGP 1054 Query: 1196 --ISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISY 1253 I + L G++ PG PG G G G PG+ G+ + S + Y Sbjct: 1055 PGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGS-------VGY 1107 Query: 1254 LTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMST 1313 SP G PG G +G PG + + + ++G S + Sbjct: 1108 PGSP-------GLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPG 1160 Query: 1314 GGGGAGSLGAGG----AFGEAAGDRGPYGTDIGPG-----GGYGAAAEGGMYAGNGGLLG 1364 G G G G F A GD+G G PG G G+ E G G Sbjct: 1161 SAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQ 1220 Query: 1365 ADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVT- 1423 G + + Q Q G PG PGP GPPG+ + + Sbjct: 1221 PGLPGSPGHATEGPKGDRGPQGQ----------PGLPGLPGPMGPPGLPGIDGVKGDKGN 1270 Query: 1424 -----ADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGD 1478 A + + QG PG G G G KGD GP G PG GP G G +G KGD Sbjct: 1271 PGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGD 1330 Query: 1479 KGDQVYAGRR 1488 +GDQ G + Sbjct: 1331 QGDQGVPGAK 1340 Score = 445 bits (1145), Expect = e-124 Identities = 352/994 (35%), Positives = 413/994 (41%), Gaps = 203/994 (20%) Query: 566 RGSPGPKGDMGSP---------GPKGDRGFPGTPGIPGPLGHPGPQGP---------KGQ 607 +G PG KGD G P GP G G+PG PG+PG G GP GP KG+ Sbjct: 72 QGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGE 131 Query: 608 KGSVGDPGMEGPMGQRGREGPMGPRGEAGP-----PGSGEKGERGAAGEPGPHGPPGVPG 662 +G +G PG+ G G G G G +G+ G PG KGERG G PG GPPG+PG Sbjct: 132 RGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPG 191 Query: 663 SVGPKGSSGSPGPQGPPGPVGLQGLRGEVGL-----PGVKGDKGPMGPPG--------PK 709 GP G G GP GPPGP G G +G++GL G KGD+G GPPG K Sbjct: 192 LQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEK 251 Query: 710 GDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPP 769 GD KG +G GEPG +G+PG VGE G G GP G G G +GE+G G P Sbjct: 252 GDFATKGEKGQKGEPGFQGMPG-VGEKGEPGKPGPRGKPGKDGDKGEKGSPGFP------ 304 Query: 770 GPSGDPGKPGLTGPQGPQ---GLPGTPGRPGI---------KGEPGAPGKIVTSEGSSML 817 G+PG PGL G QGPQ G G PG PGI KGE G PG Sbjct: 305 ---GEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPG----------- 350 Query: 818 TVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPG 877 PGP G PG G PG PG PGP G +PG G G G RG PG S+PGP G Sbjct: 351 -TPGPRGEPGPKGFPGLPGQPGPPG-LPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSG 408 Query: 878 PRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPG 936 G PG G PGPPG PG + + PGPPG GP G G PG G GE+G Sbjct: 409 RDGLPGPPGSPGPPGQPG----YTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKG--- 461 Query: 937 FSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPG 996 G S ++ G GPPGPQGP G+ G PG PGA G P G V+G PG Sbjct: 462 --QKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDG------VAGVPG 513 Query: 997 PPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFD 1056 P G PG G + G+ + Y ++ D +G PG PG PG +TG Sbjct: 514 PQGTPGLIGQPGAKGEPGEFYFDLRLKGD---------KGDPGFPGQPG----MTGRAGS 560 Query: 1057 YSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPP--GPP 1114 + + S V L + R D GP GPP GP Sbjct: 561 PGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDT---------GPPGPPGYGPA 611 Query: 1115 GASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFR 1174 G GD S + G + LPGPPG GLPG+ Sbjct: 612 GPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSP-------------- 657 Query: 1175 GIVGP------PGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGP---PGP 1225 G GP PG PG PG+PG + G+ F PGPPGP G PG Sbjct: 658 GFPGPQGDRGFPGTPGRPGLPGE----------KGAVGQPGIGF-PGPPGPKGVDGLPGD 706 Query: 1226 RGPPGVSGALATYAAENSDSFRSELISYLTSPDV-RSFIVGPPGPPGPQGPPGDSRLLST 1284 GPPG G + + + P V + G PG PG G PG+ + Sbjct: 707 MGPPGTPGRPGFNGLPGNPGVQGQ----KGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGV 762 Query: 1285 DASHSRGSSSSSHSSSVRRGSSYSSSM--STGGGGAGSLGAGGAFGEAAGDRGPYGTDIG 1342 + RG + S G G +G GA G G +GP G G Sbjct: 763 PGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGG-QGPPGLS-G 820 Query: 1343 PGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPG 1402 P G G G G G D G + + Q + G + G PG Sbjct: 821 PPGIKGE-------KGFPGFPGLDMPGP--------KGDKGAQGLPGITGQS----GLPG 861 Query: 1403 QPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPP- 1461 PG QG PGI G G+ G MGTPG G GP G P Sbjct: 862 LPGQQGAPGIP---------------------GFPGSKGEMGVMGTPGQPGSPGPVGAPG 900 Query: 1462 --------GHPGPPGPRGHKGEKGDKGDQVYAGR 1487 G PG GPRG G KGDKGD G+ Sbjct: 901 LPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGK 934 Score = 444 bits (1143), Expect = e-124 Identities = 376/1075 (34%), Positives = 450/1075 (41%), Gaps = 232/1075 (21%) Query: 567 GSPGPKGDMG--------SPGPKGDRGFPGTPGIPGPLGH-------------------- 598 GSPGP G G PGP GD+G PG PG PG +G Sbjct: 417 GSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYR 476 Query: 599 --PGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPG-------SGEKGE---- 645 PGPQGP G+ G G PG +G G GR+G G G G PG GE GE Sbjct: 477 GPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFD 536 Query: 646 ---RGAAGEPGPHGPPGVPGSVGPKGSSGSPG---PQGPPGPVGLQGLRGE---VGLPGV 696 +G G+PG G PG+ G G G G PG P+G PG VGL+G RG VG PG Sbjct: 537 LRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGS 596 Query: 697 KGDKGPMGPPG--PKGDQGEKGPRGLTGEPGMRGLPGAVGEPGA-------KGAMGPAGP 747 +GD GP GPPG P G G+KG G G PG GLPG GEPG GA G G Sbjct: 597 RGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGS 656 Query: 748 DGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGL--TGPQGPQGL---------PGTPGRP 796 G GP+G++G G PG G PG G G+PG+ GP GP+G+ PGTPGRP Sbjct: 657 PGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRP 716 Query: 797 GIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQ 856 G G PG PG + +G + +PG G PG G PG PG G G G+PG + Sbjct: 717 GFNGLPGNPG-VQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAI--- 772 Query: 857 GPPGPPGPRGPPGP-SIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPG 915 GPPG G RG PGP +PG G G PG G PG GPPG GPPG GPPG Sbjct: 773 GPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGG---------QGPPGLSGPPG 823 Query: 916 PKGDQG--------PPGPRGHQGEQGLPGFSTSGSSSFGL-NLQGPPGPPGPQGPKGDKG 966 KG++G PGP+G +G QGLPG T S GL QG PG PG G KG+ G Sbjct: 824 IKGEKGFPGFPGLDMPGPKGDKGAQGLPGI-TGQSGLPGLPGQQGAPGIPGFPGSKGEMG 882 Query: 967 ------DPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGP---------PGPPGSI---- 1007 PG PG +G P P E G SGP G PG PG PGS+ Sbjct: 883 VMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVD 942 Query: 1008 --SSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVV 1065 S GQ+ Q E Q I G +G PG PG PG G+ + Sbjct: 943 MGSMKGQKGDQ--GEKGQIGPIGE--KGSRGDPGTPGVPGKDGQ-AGQPGQPGPKGDPGI 997 Query: 1066 SYLRTSGY-GVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGS--- 1121 S T G G+ S+ + V + GP+G PG PG G Sbjct: 998 S--GTPGAPGLPGPKGSVGGMGLPGTPGEKGVPG-----IPGPQGSPGLPGDKGAKGEKG 1050 Query: 1122 --------LLSLDYAELSSRILSYMSSSGI-----SIGLPGPPGPPGLPGTSYEELLSLL 1168 + L + I + S G SIG+PG PG PGL G+ Sbjct: 1051 QAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSP-------- 1102 Query: 1169 RGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGP 1228 G VG PG PG PG G+ + L G + +PG PGP GP G +G Sbjct: 1103 ------GSVGYPGSPGLPGEKGDK----GLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGE 1152 Query: 1229 PGVSGALATYA-----------------AENSDSFRSEL--ISYLTSPDV-----RSFIV 1264 PG G + A+ + E+ SP + + Sbjct: 1153 PGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFM 1212 Query: 1265 GPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAG 1324 GPPGP G G PG S H++ +G G G +G Sbjct: 1213 GPPGPQGQPGLPG----------------SPGHATEGPKGDRGPQGQPGLPGLPGPMGPP 1256 Query: 1325 GAFG--EAAGDRGPYGTDIGPG--GGYGAAAEGGM--YAGNGGLLGADFAGDLDYNELAV 1378 G G GD+G G PG G G GM G+ G+ G+ GD+ Sbjct: 1257 GLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSK--GDMG----PP 1310 Query: 1379 RVSESMQRQGL--LQGMA-----YTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQ 1431 V +GL LQG+ V G G PGP GPPG + + Sbjct: 1311 GVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGP------ 1364 Query: 1432 TYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 +GPPG KG G PGPKG +G G G PGPPG G G G KG+ AG Sbjct: 1365 -----EGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAG 1414 Score = 431 bits (1107), Expect = e-120 Identities = 356/1084 (32%), Positives = 418/1084 (38%), Gaps = 302/1084 (27%) Query: 562 NGNLRGSPGPKGDMGSP------GPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGD-- 613 N L G PG G G P G KG+RG G PG+PG G+PGP G G KG G+ Sbjct: 104 NPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEIL 163 Query: 614 -----------------PGMEGPMGQRGREGPMGPRGEAGPPG-------SGEKGE---- 645 PG GP G G +GP+GP G GPPG GEKG+ Sbjct: 164 GHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLS 223 Query: 646 ----RGAAGEPGPHGPPGVPG----------------------------SVGPKGSSGSP 673 +G G+ G GPPGVPG VG KG G P Sbjct: 224 FQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKP 283 Query: 674 GPQGPPGPVGLQGLRGEVGLP------------GVKGDKGPMGPPGP------KGDQGEK 715 GP+G PG G +G +G G P G +G+KG GPPGP G GEK Sbjct: 284 GPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEK 343 Query: 716 GPRGLTGEPGMRGLPGAVGEPGAKGAMGP--------AGPDGHQGPRGEQGLTGMP---- 763 G RG G PG RG PG G PG G GP AG G G RGE+G G P Sbjct: 344 GERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSL 403 Query: 764 -------GIRGPPGPSGDPGKPGLT--------GPQGPQGLPGTPGRPGIKGEPGAPGKI 808 G+ GPPG G PG+PG T GP G QG PG PG+PG GE G G+ Sbjct: 404 PGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQ- 462 Query: 809 VTSEGSSMLTVPGPPGPPGAMGPPGP---PGAPGPAGPAGLPGHQEVLNLQGPPGPPGPR 865 E + + G GPPG GPPG PG PG G GLPG V + GP G PG Sbjct: 463 -KGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLI 521 Query: 866 GPPG--------------------PSIPGPPGPRGPPGE-------GLPGPPGPPGSFLS 898 G PG P PG PG G G GLPGP G PGS Sbjct: 522 GQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGL 581 Query: 899 NSETFLSGPPGPPGPPGPKGDQGPPGPRGHQ-----GEQGLPGFSTSGSSSFGLNLQGPP 953 E GPPG G PG +GD GPPGP G+ G++G GF G P Sbjct: 582 KGE---RGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGF------------PGGP 626 Query: 954 GPPGPQGPKGDKGD----PGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISS 1009 G PG GPKG+ G PG PGA G+P P G G PG PG PG G++ Sbjct: 627 GSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQ 686 Query: 1010 SGQEIQQYISEYMQSDSIRSYLSGVQGPPGP------PGPPGPVTTITGETFDYSELASH 1063 G G GPPGP PG GP T F+ Sbjct: 687 PG--------------------IGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPG 726 Query: 1064 VVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLL 1123 V G G+ L G G PG PG G+ + Sbjct: 727 VQGQKGEPGVGL--------------------------PGLKGLPGLPGIPGTPGEKGSI 760 Query: 1124 SLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPP 1183 + + GI G PGPPGLPG+ + + RG G GPP Sbjct: 761 GVPGVPGEHGAIGPPGLQGIR----GEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPP 816 Query: 1184 ---GPPGIPGNV----WSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALA 1236 GPPGI G + + + GL I G G PG PG +G PG+ G Sbjct: 817 GLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPG 876 Query: 1237 TYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSS 1296 + + E+ ++G PG PG GP G L H SS Sbjct: 877 S---------KGEM-----------GVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGP 916 Query: 1297 HSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMY 1356 +G + G + G G+ GD+G G IGP G G+ + Sbjct: 917 RGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQ-KGDQGEKG-QIGPIGEKGSRGD---- 970 Query: 1357 AGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVF 1416 G G+ G D G A G PGQPGP+G PGIS Sbjct: 971 PGTPGVPGKD-------------------------GQA----GQPGQPGPKGDPGISGTP 1001 Query: 1417 SAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEK 1476 A + GP G G MG PG G++G G PG G PG G KG K Sbjct: 1002 GA---------------PGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAK 1046 Query: 1477 GDKG 1480 G+KG Sbjct: 1047 GEKG 1050 Score = 426 bits (1094), Expect = e-118 Identities = 342/1009 (33%), Positives = 411/1009 (40%), Gaps = 176/1009 (17%) Query: 560 QENGNLRGSPGPKGDMGSPGPKGDRGF--PGTPGIPGPLGHPGPQGPKGQKGSVGDPGME 617 QE G+ + G KG G PG +G G G PG PGP G PG G KG+KGS G PG Sbjct: 249 QEKGDF-ATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEP 307 Query: 618 GPMGQRGREGPMGPRGEAGPPGS----------GEKGERG------AAGEPGPHGPPGVP 661 G G GR+GP G +GEAGPPG GEKGERG GEPGP G PG+P Sbjct: 308 GYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLP 367 Query: 662 GSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVK--------GDKGPMGPPGPKGDQG 713 G GP G PG G PG G +G +G+ G PG G GP G PGP G G Sbjct: 368 GQPGPPGLP-VPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPG 426 Query: 714 --------EKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPA----GPDGHQGPRGEQGLTG 761 + GP G G PG+ G PG +GE G KG G + DG++GP G QG G Sbjct: 427 YTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPG 486 Query: 762 MPGIRGPPGPSGD---PGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLT 818 G G PG GD PG+ G+ G GPQG PG G+PG KGEPG + +G Sbjct: 487 EIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDP 546 Query: 819 -VPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGP---PGPRGPPGPSIPG 874 PG PG G G PG G PG GP G PG + +GPPG PG RG GP PG Sbjct: 547 GFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGP--PG 604 Query: 875 PPG---------------PRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGD 919 PPG P GP GLPGP G PG + L GPPG G PG G Sbjct: 605 PPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVP-----LPGPPGAEGLPGSPGF 659 Query: 920 QGPPGPRGHQGEQGLPGF--STSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALG-- 975 GP G RG G G PG G+ GPPGP G G GD G PG PG G Sbjct: 660 PGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFN 719 Query: 976 -IPSGPSEGGSSSTMYVSGP-----PGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRS 1029 +P P G V P PG PG PG PG S G + E+ Sbjct: 720 GLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIG--VPGVPGEHGAIGP--P 775 Query: 1030 YLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILA 1089 L G++G PGPPG PG S+ S + Sbjct: 776 GLQGIRGEPGPPGLPG-----------------------------------SVGSPGVPG 800 Query: 1090 VLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPG 1149 + GP G GPPG G L + + + +PG Sbjct: 801 I---------------GPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFP-----GLDMPG 840 Query: 1150 PPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAG 1209 P G G G L + S G+ G G PG PG PG+ + + T G Sbjct: 841 PKGDKGAQG-----LPGITGQSGLPGLPGQQGAPGIPGFPGS-------KGEMGVMGTPG 888 Query: 1210 LSFIPGPPGPPGPP------------GPRGPPGVSGALATYAAE----NSDSFRSELISY 1253 PGP G PG P GPRG PG+ G + D + Sbjct: 889 QPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKG 948 Query: 1254 LTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMST 1313 +GP G G +G PG + D + G+ + + Sbjct: 949 QKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPG 1008 Query: 1314 GGGGAGSLGAGGAFGE--AAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDL 1371 G G +G G GE G GP G+ G G GA E G AG G+ G+ Sbjct: 1009 PKGSVGGMGLPGTPGEKGVPGIPGPQGSP-GLPGDKGAKGEKGQ-AGPPGIGIPGLRGEK 1066 Query: 1372 DYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQ 1431 +A ++ + + + G PG PG +G PG S + + + D + Sbjct: 1067 GDQGIAGFPGSPGEKG---EKGSIGIPGMPGSPGLKGSPG-SVGYPGSPGLPGEKGD--K 1120 Query: 1432 TYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKG 1480 + G PG KGE G PG G GPAG G PG G G GEKG+ G Sbjct: 1121 GLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPG 1169 Score = 424 bits (1089), Expect = e-118 Identities = 334/978 (34%), Positives = 400/978 (40%), Gaps = 252/978 (25%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPG-----------PLGHPGPQGPKGQKGSVGD-- 613 G+ G G G PGP+GDRGFPGTPG PG +G PGP GPKG G GD Sbjct: 649 GAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMG 708 Query: 614 -PGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGS 672 PG G G G G G +G+ G PG G G +G G P G PG PG G G G Sbjct: 709 PPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLP---GIPGTPGEKGSIGVPGV 765 Query: 673 PGPQGPPGPVGLQGLRGEVGLPGVKGDKGP-----MGPPGPKGDQGEKGPRGLTGEPGMR 727 PG G GP GLQG+RGE G PG+ G G +GPPG +G G +GP GL+G PG++ Sbjct: 766 PGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIK 825 Query: 728 GLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQ 787 G G G PG + GP G +G +G G+TG G+ G PG G PG PG G +G Sbjct: 826 GEKGFPGFPG----LDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEM 881 Query: 788 GLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGP---PGAMGPPGPPGAPGPAGPA 844 G+ GTPG+PG G GAPG +PG G PG+ GP G PG G G Sbjct: 882 GVMGTPGQPGSPGPVGAPG------------LPGEKGDHGFPGSSGPRGDPGLKGDKGDV 929 Query: 845 GLP------------------GHQEVLNLQGPPGPPGPRGPPG-PSIPGPPGPRGPPGEG 885 GLP G Q GP G G RG PG P +PG G G PG+ Sbjct: 930 GLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQ- 988 Query: 886 LPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSF 945 PGP G PG +SG PG PG PGPKG G G G GE+G+PG Sbjct: 989 -PGPKGDPG---------ISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIP------- 1031 Query: 946 GLNLQGPPGPPGPQGPKGDKGDPGVP--------------GALGIPSGPSEGGSSSTMYV 991 QG PG PG +G KG+KG G P G G P P E G ++ + Sbjct: 1032 --GPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGI 1089 Query: 992 SGPPGPPGPPGPPGSI---SSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVT 1048 G PG PG G PGS+ S G ++ D I GV+G G PG PGP Sbjct: 1090 PGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGI----PGVKGEAGLPGTPGP-- 1143 Query: 1049 TITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPR 1108 TG E S + S+ E L R Sbjct: 1144 --TGPAGQKGEPGSDGIP-----------GSAGEKGEPGLP-----------------GR 1173 Query: 1109 GPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLL 1168 G PG PGA GD S +G PG G PG+PG+ E+ Sbjct: 1174 GFPGFPGAKGD-------------------KGSKGEVGFPGLAGSPGIPGSKGEQ----- 1209 Query: 1169 RGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGP---PGPPGPPGP 1225 G +GPPGP G PG+PG+ + T G GP PG PG PGP Sbjct: 1210 ------GFMGPPGPQGQPGLPGSPGHA-----------TEGPKGDRGPQGQPGLPGLPGP 1252 Query: 1226 RGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTD 1285 GPPG+ G + + + G PG PGP+G PG + Sbjct: 1253 MGPPGLPGIDGVKGDKGNPGW-----------------PGAPGVPGPKGDPGFQGMPGIG 1295 Query: 1286 ASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGG 1345 S S +G + G G G G G+ GD+G G G G Sbjct: 1296 GSPGITGS---------KGDMGPPGVPGFQGPKGLPGLQGIKGD-QGDQGVPGAK-GLPG 1344 Query: 1346 GYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPG 1405 G + G GL G + L +G G PG Sbjct: 1345 PPGPPGPYDIIKGEPGLPGPEGPPGL--------------------------KGLQGLPG 1378 Query: 1406 PQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPP---G 1462 P+G G++ + I GPPG G G PG KG+ GPAGP G Sbjct: 1379 PKGQQGVTGLV------------------GIPGPPGIPGFDGAPGQKGEMGPAGPTGPRG 1420 Query: 1463 HPGPPGPRGHKGEKGDKG 1480 PGPPGP G G G G Sbjct: 1421 FPGPPGPDGLPGSMGPPG 1438 Score = 404 bits (1038), Expect = e-112 Identities = 333/970 (34%), Positives = 405/970 (41%), Gaps = 227/970 (23%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPG--------------IPGPLGHPGPQGPKGQKGS 610 L+G GP G +G PG +GD G PG PG PG G PG GPKG+ G Sbjct: 581 LKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGK 640 Query: 611 V----GDPGMEGPMGQRGREGPMGPRGEAGPPGS-GEKGERGAAGEPG--------PHGP 657 + G PG EG G G GP G RG G PG G GE+GA G+PG P G Sbjct: 641 IVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGV 700 Query: 658 PGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGE--VGLPGVKG------------DKGPM 703 G+PG +GP G+ G PG G PG G+QG +GE VGLPG+KG +KG + Sbjct: 701 DGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSI 760 Query: 704 GPPGPKGDQGEKGP---RGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLT 760 G PG G+ G GP +G+ GEPG GLPG+VG PG G +GP G G G +G GL+ Sbjct: 761 GVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPG-IGPPGARGPPGGQGPPGLS 819 Query: 761 GMPGIRGP-----------PGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIV 809 G PGI+G PGP GD G GL G G GLPG PG+ G G PG PG Sbjct: 820 GPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPG--- 876 Query: 810 TSEGS-SMLTVPGPPGPPGAMGPPGPPGA------PGPAGPAGLPGHQEVLNLQGPPGPP 862 S+G ++ PG PG PG +G PG PG PG +GP G PG + G PG P Sbjct: 877 -SKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKP 935 Query: 863 GP------------------------------RGPPG-PSIPGPPGPRGPPGEGLPGPPG 891 G RG PG P +PG G G PG+ PGP G Sbjct: 936 GSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQ--PGPKG 993 Query: 892 PPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQG 951 PG +SG PG PG PGPKG G G G GE+G+PG QG Sbjct: 994 DPG---------ISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGP---------QG 1035 Query: 952 PPGPPGPQGPKGDKGDPGVPGA--------------LGIPSGPSEGGSSSTMYVSGPPGP 997 PG PG +G KG+KG G PG G P P E G ++ + G PG Sbjct: 1036 SPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGS 1095 Query: 998 PGPPGPPGSIS---SSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGET 1054 PG G PGS+ S G ++ D I GV+G G PG PGP TG Sbjct: 1096 PGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGI----PGVKGEAGLPGTPGP----TGPA 1147 Query: 1055 FDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPP 1114 E S + S+ E L RG PG P Sbjct: 1148 GQKGEPGSDGIPG-----------SAGEKGEPGLP-----------------GRGFPGFP 1179 Query: 1115 GASGD-GSLLSLDYAEL--SSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLL--R 1169 GA GD GS + + L S I G +G PGP G PGLPG+ R Sbjct: 1180 GAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGF-MGPPGPQGQPGLPGSPGHATEGPKGDR 1238 Query: 1170 GSEFR-GIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGP 1228 G + + G+ G PGP GPPG+PG ++ + G PG PGP G PG +G Sbjct: 1239 GPQGQPGLPGLPGPMGPPGLPG-------IDGVKGDKGNPGWPGAPGVPGPKGDPGFQGM 1291 Query: 1229 PGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASH 1288 PG+ G+ ++ +GPPG PG QGP G L Sbjct: 1292 PGIGGSPGITGSKGD--------------------MGPPGVPGFQGPKGLPGLQGI---- 1327 Query: 1289 SRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYG 1348 +G + G G G G + G+ G G + GP G G Sbjct: 1328 --------------KGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPE-GPPGLKG 1372 Query: 1349 AAAEGGMYAGNG--GLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYT-VQGPPGQPG 1405 G G GL+G + + A M G + GP G PG Sbjct: 1373 LQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPG 1432 Query: 1406 PQGPPGISKV 1415 GPPG V Sbjct: 1433 SMGPPGTPSV 1442 Score = 394 bits (1013), Expect = e-109 Identities = 300/835 (35%), Positives = 357/835 (42%), Gaps = 151/835 (18%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGRE 626 G+PG KG +G PG G+ G G PG+ G G PGP G G GS G PG+ GP G RG Sbjct: 752 GTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGI-GPPGARGPP 810 Query: 627 GPMGPRGEAGPPG-SGEKGERGAAG--EPGPHGPPG---VPGSVGPKGSSGSPGPQGPPG 680 G GP G +GPPG GEKG G G PGP G G +PG G G G PG QG PG Sbjct: 811 GGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPG 870 Query: 681 PVGLQGLRGEVGLPGVKGDKGPMGP------PGPKGDQGEKGPRGLTGEPGMRGLPGAVG 734 G G +GE+G+ G G G GP PG KGD G G G G+PG++G G VG Sbjct: 871 IPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVG 930 Query: 735 EPGAKGAM------------GPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTG 782 PG G+M G G G GP GE+G G PG G PG G G+PG G Sbjct: 931 LPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPG 990 Query: 783 PQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAP---- 838 P+G G+ GTPG PG+ G G+ G G + PG G PG GP G PG P Sbjct: 991 PKGDPGISGTPGAPGLPGPKGSVG------GMGLPGTPGEKGVPGIPGPQGSPGLPGDKG 1044 Query: 839 -----GPAGP-----AGLPGHQEVLNLQGPPGPPGPRGPPG----PSIPGPPGPRGPPGE 884 G AGP GL G + + G PG PG +G G P +PG PG +G PG Sbjct: 1045 AKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGS 1104 Query: 885 -GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGE---QGLPGFSTS 940 G PG PG PG L G PG G G G GP GP G +GE G+PG S Sbjct: 1105 VGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPG-SAG 1163 Query: 941 GSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGP 1000 GL +G PG PG +G KG KG+ G PG G P P G M GPPGP G Sbjct: 1164 EKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFM---GPPGPQGQ 1220 Query: 1001 PGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSEL 1060 PG PGS + +E + D G+ G PGP GPPG + I G D Sbjct: 1221 PGLPGS--------PGHATEGPKGDRGPQGQPGLPGLPGPMGPPG-LPGIDGVKGDKGNP 1271 Query: 1061 ----ASHVVSYLRTSGY----GVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPG 1112 A V G+ G+ S+ G GPPG Sbjct: 1272 GWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSK--------------------GDMGPPG 1311 Query: 1113 PPGASGDGSLLSLDYAELSSRILSYMSSSGI--SIGLPGPPGPPGLPGTSYEELLSLLRG 1170 PG G L L I G+ + GLPGPPGPPG Y+ + Sbjct: 1312 VPGFQGPKGLPGL------QGIKGDQGDQGVPGAKGLPGPPGPPG----PYDII------ 1355 Query: 1171 SEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPG 1230 +G G PGP GPPG+ G ++ L G++ + G PGPPG PG G PG Sbjct: 1356 ---KGEPGLPGPEGPPGLKG-------LQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPG 1405 Query: 1231 VSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSR 1290 G + F PGPPGP G PG + Sbjct: 1406 QKGEMGPAGPTGPRGF--------------------PGPPGPDGLPG--------SMGPP 1437 Query: 1291 GSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGG 1345 G+ S H V R S G L G + G+ +G D+G G Sbjct: 1438 GTPSVDHGFLVTRHSQTIDDPQC-PSGTKILYHGYSLLYVQGNERAHGQDLGTAG 1491 Score = 367 bits (941), Expect = e-101 Identities = 225/557 (40%), Positives = 275/557 (49%), Gaps = 92/557 (16%) Query: 559 EQENGNLRGSPGPKGDM---------GSPGPKGDRGFPGT------PGIPGPLGHPGPQG 603 +Q + G PG KG+M GSPGP G G PG PG GP G PG +G Sbjct: 865 QQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKG 924 Query: 604 PKGQKGSVGDP------------GMEGPMGQRGREGPMGPRGEAGPPGS-GEKGERGAAG 650 KG G G P G +G G++G+ GP+G +G G PG+ G G+ G AG Sbjct: 925 DKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAG 984 Query: 651 EPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKG 710 +PG GP G PG G G+ G PGP+G G +GL G GE G+PG+ GP G PG G Sbjct: 985 QPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGI---PGPQGSPGLPG 1041 Query: 711 DQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGM---PGIRG 767 D+G KG +G G PG+ G+PG GE G +G G G G +G +G G+ GM PG++G Sbjct: 1042 DKGAKGEKGQAGPPGI-GIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKG 1100 Query: 768 PPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPG 827 PG G PG PGL G +G +GLPG G PG+KGE G PG + + PG G PG Sbjct: 1101 SPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPG 1160 Query: 828 AMGPPGPPGAPGP-----------------------AGPAGLPGHQEVLNLQGPPGP--- 861 + G G PG PG AG G+PG + GPPGP Sbjct: 1161 SAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQ 1220 Query: 862 PGPRGPPGPSIPGPPGPRGPPGE----GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPK 917 PG G PG + GP G RGP G+ GLPGP GPPG + G G G PG Sbjct: 1221 PGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGL------PGIDGVKGDKGNPGWP 1274 Query: 918 GDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGP---------KGDKGDP 968 G G PGP+G G QG+PG S + GPPG PG QGP KGD+GD Sbjct: 1275 GAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQ 1334 Query: 969 GVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIR 1028 GVPGA G+P P G + G PG PGP GPPG G + + Sbjct: 1335 GVPGAKGLPGPPGPPGPYD--IIKGEPGLPGPEGPPGLKGLQG----------LPGPKGQ 1382 Query: 1029 SYLSGVQGPPGPPGPPG 1045 ++G+ G PGPPG PG Sbjct: 1383 QGVTGLVGIPGPPGIPG 1399 Score = 345 bits (885), Expect = 2e-94 Identities = 221/537 (41%), Positives = 266/537 (49%), Gaps = 94/537 (17%) Query: 557 MMEQENGNLRGSPGPKGDMGSPGP---KGDRGFPGTPGIPGP---LGHPGPQGPKGQ--- 607 M + + G+++G G +G+ G GP KG RG PGTPG+PG G PG GPKG Sbjct: 938 MDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGI 997 Query: 608 ------------KGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGS-GEKGERGAAGEPGP 654 KGSVG G+ G G++G G GP+G G PG G KGE+G AG PG Sbjct: 998 SGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGI 1057 Query: 655 HGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGE 714 G PG+ G G +G +G PG G G G G+ G G PG+KG G +G PG G GE Sbjct: 1058 -GIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGE 1116 Query: 715 KGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGD 774 KG +GL G G+ G+ G G PG G GPA G +GE G G+PG G G G Sbjct: 1117 KGDKGLPGLDGIPGVKGEAGLPGTPGPTGPA------GQKGEPGSDGIPGSAGEKGEPGL 1170 Query: 775 PGK--PGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPP 832 PG+ PG G +G +G G G PG+ G PG PG S+G G GPPG G P Sbjct: 1171 PGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPG----SKGEQ-----GFMGPPGPQGQP 1221 Query: 833 GPPGAPGPA--GPAGLPGHQEVLNLQGPPGPPGPRGPPG-------------PSIPGPPG 877 G PG+PG A GP G G Q L G PGP GP G PG P PG PG Sbjct: 1222 GLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPG 1281 Query: 878 PRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPG 936 P+G PG +G+PG G PG S + GPPG PG GPKG G G +G QG+QG+PG Sbjct: 1282 PKGDPGFQGMPGIGGSPGITGSKGD---MGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPG 1338 Query: 937 FSTSGSSSFGLNLQGPPGPPGP-------QGPKGDKGDPGVPGALGIPSGPSEGGSSSTM 989 L GPPGPPGP G G +G PG+ G G+P + G + + Sbjct: 1339 ---------AKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLV 1389 Query: 990 YVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGP 1046 + GPPG PG G PG G +G GP G PGPPGP Sbjct: 1390 GIPGPPGIPGFDGAPGQKGEMGP-------------------AGPTGPRGFPGPPGP 1427 Score = 345 bits (884), Expect = 2e-94 Identities = 309/939 (32%), Positives = 370/939 (39%), Gaps = 197/939 (20%) Query: 668 GSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMR 727 G G +G G GL GL+G +G PG++G +GP GPPG K G+ G GL G G R Sbjct: 37 GKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQK---GDTGEPGLPGTKGTR 93 Query: 728 GLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQ 787 G PGA G PG G G G DG GP G G G G RGP GP PG PG G GP Sbjct: 94 GPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGP---PGLPGFAGNPGPP 150 Query: 788 GLPGTPGRPG----------IKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGA 837 GLPG G PG +KGE G PG T + + GP GPPG GPPGPPG Sbjct: 151 GLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGP 210 Query: 838 PGP-----------------------AGPAGLPGHQEVLNL--------QGPPGPPGPRG 866 PGP +GP G+PG +V +G G PG +G Sbjct: 211 PGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQG 270 Query: 867 PPG---PSIPGPPGPRGPPGE----------GLPGPPGPPGSFLSNS---ETFLSGPPGP 910 PG PG PGPRG PG+ G PG PG PG E +GPPGP Sbjct: 271 MPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGP 330 Query: 911 PG------PPGPKGDQG---PPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGP 961 PG P G KG++G PGPRG G +G PG GL + G G PG G Sbjct: 331 PGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPP-GLPVPGQAGAPGFPGE 389 Query: 962 KGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEY 1021 +G+KGD G PG S G S + GPPG PGPPG PG + I E Sbjct: 390 RGEKGDRGFPGT-------SLPGPSGRDGLPGPPGSPGPPGQPGYTNG--------IVEC 434 Query: 1022 MQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSE--LASHVVSYLRTSGY----GV 1075 G QGPPG PG PG + I GE E L + Y G G Sbjct: 435 QPGPP------GDQGPPGIPGQPGFIGEI-GEKGQKGESCLICDIDGYRGPPGPQGPPGE 487 Query: 1076 SLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPG---PPGASGDGSLLSLDYAELSS 1132 F ++ + RD V + GP+G PG PGA G+ D Sbjct: 488 IGFPGQPGAKGDRGLPGRDGVAG-----VPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGD 542 Query: 1133 R-ILSYMSSSGIS--IGLPGPPGPPGLPGTSYEELLSLLRGSE-------FRGIVGPPGP 1182 + + G++ G PG G PGLPG L+G F G G GP Sbjct: 543 KGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGP 602 Query: 1183 PGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAEN 1242 PGPPG + + G + PG PG PG PGP+G PG Sbjct: 603 PGPPGYGP-----------AGPIGDKGQAGFPGGPGSPGLPGPKGEPGK----------- 640 Query: 1243 SDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVR 1302 IV PGPPG +G PG + Sbjct: 641 --------------------IVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGE 680 Query: 1303 RGSSYSSSMSTGGGGAGSLGAGGAFGEAA--GDRGPYGTDIGPG--------GGYGAAAE 1352 +G+ G G G G G G GD GP GT PG G G E Sbjct: 681 KGA-------VGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGE 733 Query: 1353 GGM-YAGNGGLLGADFAGDLDYNELAVRVSESMQRQGL-----LQGMAYTVQGPPGQPGP 1406 G+ G GL G + ++ V G LQG+ GPPG PG Sbjct: 734 PGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGE-PGPPGLPGS 792 Query: 1407 QGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMG--------TPGPKGDRGPA 1458 G PG+ + + Q + GPPG KGE G PGPKGD+G Sbjct: 793 VGSPGVPGIGPPGARGPPG----GQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQ 848 Query: 1459 GPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 G PG G G G G++G G + G + + P Sbjct: 849 GLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTP 887 Score = 207 bits (528), Expect = 5e-53 Identities = 134/317 (42%), Positives = 157/317 (49%), Gaps = 58/317 (18%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGT--PGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQR 623 +G PG G GS G KG+ G PG PG PG G G +G G G G PG+ G G++ Sbjct: 1150 KGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQ 1209 Query: 624 GREGPMGPRGEAGPPGS------GEKGERGAAGEPG------PHGPPGVPGSVGPKGSSG 671 G GP GP+G+ G PGS G KG+RG G+PG P GPPG+PG G KG G Sbjct: 1210 GFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKG 1269 Query: 672 SPG------PQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTG--- 722 +PG GP G G QG+ G G PG+ G KG MGPPG G QG KG GL G Sbjct: 1270 NPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKG 1329 Query: 723 ------EPGMRGLPGAVGEPGA-------KGAMGPAGPDGHQG------PRGEQGLTGMP 763 PG +GLPG G PG G GP GP G +G P+G+QG+TG+ Sbjct: 1330 DQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLV 1389 Query: 764 GIRGPPGPSGDPGKPGL---------TGPQG---PQGLPGTPGRPGIKGEPGAP-GKIVT 810 GI GPPG G G PG TGP+G P G G PG G G P G +VT Sbjct: 1390 GIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSVDHGFLVT 1449 Query: 811 SEGSSMLTVPGPPGPPG 827 T+ P P G Sbjct: 1450 RHSQ---TIDDPQCPSG 1463 >gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo sapiens] Length = 1424 Score = 449 bits (1156), Expect = e-126 Identities = 354/1008 (35%), Positives = 421/1008 (41%), Gaps = 185/1008 (18%) Query: 563 GNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHP---GPQGPKGQKGSVGDPGME-- 617 G+ +G+PG G G PG G GFPG+ G+ G G P G G KGQKG +G PG Sbjct: 284 GSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGP 343 Query: 618 -------------------GPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPG----- 653 GP G RG +GP GP G G PGS G RGA G PG Sbjct: 344 TEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSK 403 Query: 654 ---------PHGPPGVPGSVGPKGSSGSPGPQGPP-------GPVGLQGLRGEVGLPGVK 697 G PG PG G G GSPGP GPP GP G GL G +G PG+ Sbjct: 404 GERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIP 463 Query: 698 GDKGPMGPPGPKGDQ-----GEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQG 752 G GP G PG Q G G GL G G++G+PG G G KG+ G G G G Sbjct: 464 GVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPG 523 Query: 753 PRGEQGLTGMPGIRG-------PPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAP 805 G G G PG++G P G G PG PGL G G +GL G PG PG+KG PG Sbjct: 524 FPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPK 583 Query: 806 GKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPR 865 G++ S PG PG PG+ GP GP G PG GP G PG Q + G PGPPG Sbjct: 584 GELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGTQGVPGAPGPPGEA 642 Query: 866 GPPG-----PSIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGD 919 GP G +PGPPGP GPPG G GPPG PGS + L GP G PG PG G Sbjct: 643 GPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG-IGF 701 Query: 920 QGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGV--PGALGIP 977 GPPGP+ G+QG PG T GS G PG PG G G KG+P V PG G P Sbjct: 702 PGPPGPK---GDQGFPG--TKGSLGCP-GKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTP 755 Query: 978 SGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGP 1037 P E G+S G PG PG PG PG+ G G G Sbjct: 756 GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR-------------------GDPGQ 796 Query: 1038 PGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVR 1097 PGPPG GP G + A + G Sbjct: 797 PGPPGEQGP----PGRCIEGPRGAQGLPGLNGLKG------------------------- 827 Query: 1098 QYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLP 1157 Q R+ GP+G PG PG G S I + G +G G PG PG+ Sbjct: 828 QQGRRGKTGPKGDPGIPGLDRSG----FPGETGSPGIPGHQGEMG-PLGQRGYPGNPGIL 882 Query: 1158 GTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPP 1217 G E+ + + G F G +GPPGPPG PG PG S + + T G G Sbjct: 883 GPPGEDGVIGMMG--FPGAIGPPGPPGNPGTPGQ-RGSPGIPGVKGQRGTPGAKGEQGDK 939 Query: 1218 GPPGPP------GPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPG 1271 G PGP G +G PG+ G + + P ++ + G PGP G Sbjct: 940 GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG-------MPGLKG-LKGLPGPAG 991 Query: 1272 PQGPPGDSRLLSTDASHSRGSSSSSHSSSVR--RGSSYSSSMSTGGGGAGSLGAGGAFGE 1329 P GP GD GS+ + +R GS + M G G+LG G G Sbjct: 992 PPGPRGD-----------LGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR 1040 Query: 1330 AA--GDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQ 1387 G G G PG G G+ GL GD+ M + Sbjct: 1041 PGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL-----PGDMG-------KKGEMGQP 1088 Query: 1388 GLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMG 1447 G + GP G PG G PG+ + ++ + I+GPPG G G Sbjct: 1089 GPPGHLG--PAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPG 1146 Query: 1448 TPGPKGDRGPAGPPGHPG-------------PPGPRGHKGEKGDKGDQ 1482 +PGP G RG G G PG PPGPRG+ G +G KGD+ Sbjct: 1147 SPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDR 1194 Score = 449 bits (1155), Expect = e-126 Identities = 380/1134 (33%), Positives = 453/1134 (39%), Gaps = 263/1134 (23%) Query: 560 QENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPL--------GHPGPQGPKGQKG-- 609 QE G+ G+PGP G G+ GP+G G PG PG PG G PG +G KG++G Sbjct: 351 QEKGD-EGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRP 409 Query: 610 ------SVGDPGMEGPMGQRGREGPMGPRGEA----GPPGS----------GEKGERGAA 649 + G PG G G G GP GP G+ GPPG G G G Sbjct: 410 GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPK 469 Query: 650 GEPG------PH--GPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKG 701 GEPG P+ GPPG+PG G G G PG QG G G G G GLPG G G Sbjct: 470 GEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPG 529 Query: 702 PMGPPGPKGDQGEK----------GPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQ 751 G PG KG++GE G GL G+PG +GL G G PG KG GP G Sbjct: 530 AQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALS 589 Query: 752 GPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTS 811 G +G+QG G PG G PGP+G G PG GPQG GL GT G PG G PG G Sbjct: 590 GEKGDQGPPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVPGAPGPPGEAGP--RG 646 Query: 812 EGSSMLTVPGPPGPPGAMGPPGP--------------------------------PGAPG 839 E S VPGPPGPPG G PGP PG PG Sbjct: 647 ELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPG 706 Query: 840 PAGPAGLPGHQEVLN---------LQGPPGPPGPRGPPGPSIPGPPGPRGPPGE------ 884 P G G PG + L L G PG PG +G P ++PG PG G PGE Sbjct: 707 PKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGE 766 Query: 885 ----GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPG-----PRGHQG----- 930 GLPG PG PG+ L GP G PG PGP G+QGPPG PRG QG Sbjct: 767 HGEIGLPGLPGLPGT---PGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLN 823 Query: 931 ----------------EQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGAL 974 + G+PG SG G PG G GP G +G PG PG L Sbjct: 824 GLKGQQGRRGKTGPKGDPGIPGLDRSGFPG-ETGSPGIPGHQGEMGPLGQRGYPGNPGIL 882 Query: 975 GIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSG----------------------- 1011 G P G GPPGPPG PG PG S G Sbjct: 883 GPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNP 942 Query: 1012 --QEIQQYISEYMQSDSIRSY-----------------LSGVQGPPGPPGPPGPVTTITG 1052 EI I + + ++ + L G++G PGP GPPGP + G Sbjct: 943 GPSEISHVIGDKGEP-GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL-G 1000 Query: 1053 ETFDYSELASH-VVSYLRTSGY-------GVSLFSSSISSEDILAV--LQRDDVRQ-YLR 1101 T + E + + G G F + + LQ D Y Sbjct: 1001 STGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSE 1060 Query: 1102 QYLMGPRGPPGPPGASGDGSLLSLDYAELSSR-ILSYMSSSGISIGLPGPPGPPGLPGTS 1160 GP GP G PG GD E+ ++ +G G PG PG PGLPG Sbjct: 1061 GTRPGPPGPTGDPGLPGDMG----KKGEMGQPGPPGHLGPAGPE-GAPGSPGSPGLPGKP 1115 Query: 1161 YEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPP 1220 +G +G++GPPG GPPG+PG S + G IPGP G Sbjct: 1116 GPHGDLGFKG--IKGLLGPPGIRGPPGLPGFPGSPGPM----GIRGDQGRDGIPGPAGEK 1169 Query: 1221 G-------PPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQ 1273 G PPGPRG PG GA A R +G GP GP Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPG-----------RKGAMGDAGPRGPT 1218 Query: 1274 G------PPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAF 1327 G PPG + + +RG S RGS + G G+ +G G Sbjct: 1219 GIEGFPGPPGLPGAIIPGQTGNRGPPGS-------RGSPGAPG-PPGPPGSHVIGIKGDK 1270 Query: 1328 GEAA--GDRGPYGT--DIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSES 1383 G G +GP GT D+GP G GA G+ G F G V Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG----------VKGE 1320 Query: 1384 MQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQK 1443 G L + GPPG GP+GPPG+ ++ + G PG Sbjct: 1321 KGNPGFLGSI-----GPPGPIGPKGPPGVRGDPGTLKIIS------------LPGSPGPP 1363 Query: 1444 GEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 G G PG +G+ GP GPPG+ GP GPRG G+ G G AG + + +P Sbjct: 1364 GTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEP 1417 Score = 419 bits (1076), Expect = e-116 Identities = 350/1027 (34%), Positives = 412/1027 (40%), Gaps = 240/1027 (23%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGH------PGPQGPKGQKGSVGDPGMEGP 619 +G G KG G PG G +GF G G+PGP G PG G KG +G G PG G Sbjct: 45 KGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGS 104 Query: 620 MGQRGREGPMGPRGEAGPPG-SGEKGERGAAGEPGPHGPPGVPGSVGPKGSS-------- 670 G G G GP G G PG SG KGE+G G PG G PG+PG+ G KG Sbjct: 105 PGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164 Query: 671 ------------GSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGE---- 714 G+PGPQG PGP G G G G PG G G MGP GPKG GE Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIG 224 Query: 715 -KGPRGLTGEPGMRGLPGAV--------------GEPGAKGAMGPAGPDGHQGPRG---- 755 KG RG+ G G G PG V GE G KGAMG GP G G G Sbjct: 225 HKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYG 284 Query: 756 -EQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGK------- 807 E+G G PG++G PG G PG PG G +G +G PG G GIKG+ G G Sbjct: 285 SEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPT 344 Query: 808 --IVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAG--LPGHQEVLNLQGPPGPPG 863 T + PGPPGP GA GP GP G PG G G PG + G G G Sbjct: 345 EYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKG 404 Query: 864 PRGPPGP---SIPGPPGPRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGD 919 RG PG PG PG G PG G PGPPGPPG + F GPPG G PG G Sbjct: 405 ERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIV-----FRKGPPGDHGLPGYLGS 459 Query: 920 QGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSG 979 G PG G +GE GL + GPPG PG G G KG PG GA G+ Sbjct: 460 PGIPGVDGPKGEPGLLCTQCP-------YIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGS 512 Query: 980 PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSD------SIRSYLSG 1033 P G++ + G PG PG G PG G+ +Q + D R L G Sbjct: 513 PGSPGNTG---LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDG 569 Query: 1034 VQGPPGPPGPPGP--VTTITGETFDY-------SELASHVVSYLRTSGYGVSLFSSSISS 1084 + G PG G PGP ++GE D S + GYG Sbjct: 570 IPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGP-------QG 622 Query: 1085 EDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGIS 1144 E L Q G G PGPPG +G LS +S Sbjct: 623 EPGL-------------QGTQGVPGAPGPPGEAGPRGELS------------------VS 651 Query: 1145 IGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSY 1204 +PGPPGPPG P G PGP GPPGIPG+ Sbjct: 652 TPVPGPPGPPGPP--------------------GHPGPQGPPGIPGS------------- 678 Query: 1205 LHTAGLSFIPGP-----------PGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISY 1253 L G +PGP PGPPGP G +G PG G+L Sbjct: 679 LGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG-------- 730 Query: 1254 LTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMST 1313 + G PG PG +G P ++ +S G + Sbjct: 731 ---------LPGKPGLPGAKGEPA----VAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG 777 Query: 1314 GGGGAGSLGAGGAFGEAA-----GDRGPYGTDI-GPGGGYGAAAEGGMYA---------- 1357 G G+ G G G+ G++GP G I GP G G G+ Sbjct: 778 LPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGP 837 Query: 1358 -GNGGLLGAD---FAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGIS 1413 G+ G+ G D F G+ + QG + + +G PG PG GPPG Sbjct: 838 KGDPGIPGLDRSGFPGETGSPGIP-------GHQGEMGPLGQ--RGYPGNPGILGPPGED 888 Query: 1414 KVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHK 1473 V +M F GAI GPPG G GTPG +G G G G G PG +G + Sbjct: 889 GVIG--------MMGF---PGAI-GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQ 936 Query: 1474 GEKGDKG 1480 G+KG+ G Sbjct: 937 GDKGNPG 943 Score = 368 bits (944), Expect = e-101 Identities = 261/702 (37%), Positives = 302/702 (43%), Gaps = 179/702 (25%) Query: 566 RGSPGPKGDMGSPGPKGDR-GFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 RG GPKGD G PG DR GFPG G PG GH G GP GQ+G G+PG+ GP G+ G Sbjct: 832 RGKTGPKGDPGIPGL--DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889 Query: 625 REGPMGPRGEAGPPGS----GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQ---- 676 G MG G GPPG G G+RG+ G PG G G PG+ G +G G+PGP Sbjct: 890 VIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949 Query: 677 --GPPGPVGLQGL---------RGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPG 725 G G GL+G RG G+PG+KG KG GP GP G +G+ G G GEPG Sbjct: 950 VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009 Query: 726 MRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRG--------------PPGP 771 +RG+PG++G G G+ G G G G G GL G+ G++G PPGP Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP 1069 Query: 772 SGDPG---------------KPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSM 816 +GDPG PG GP GP+G PG+PG PG+ G+PG G + Sbjct: 1070 TGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL------GF 1123 Query: 817 LTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPG----------PPGPRG 866 + G GPPG GPPG PG PG GP G+ G Q + GP G PPGPRG Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRG 1183 Query: 867 PPGPSIPGPPGPRGPPG-EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGP-----KGDQ 920 PG G G RG PG GLPG G G T + G PGPPG PG G++ Sbjct: 1184 NPGAQ--GAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNR 1241 Query: 921 GPPGPRGHQGEQGLPGFSTSGSSSFGLNL-QGPPGPPGPQGPKGDKGDPGVPGALGIPSG 979 GPPG RG G G PG GS G+ +G G PGP+GP G GD G PG LG P Sbjct: 1242 GPPGSRGSPGAPGPPG--PPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGT 1299 Query: 980 PSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPG 1039 P G G PG G G PG + S G G +GPPG Sbjct: 1300 PGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGP----------------IGPKGPPG 1343 Query: 1040 PPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQY 1099 G PG + I+ Sbjct: 1344 VRGDPGTLKIIS------------------------------------------------ 1355 Query: 1100 LRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGT 1159 L G GPPG PG G G PGPPGPPG G Sbjct: 1356 ----LPGSPGPPGTPGEPG-------------------------MQGEPGPPGPPGNLGP 1386 Query: 1160 SYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDL 1201 RG G G PG PGP G GN S E L Sbjct: 1387 CGP------RGKP--GKDGKPGTPGPAGEKGNKGSKGEPESL 1420 Score = 337 bits (865), Expect = 4e-92 Identities = 234/601 (38%), Positives = 268/601 (44%), Gaps = 136/601 (22%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG 624 L GS G +G G PG G G PGTPG GP G G G G KG G PG+ G +G G Sbjct: 86 LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145 Query: 625 REGPMGPRGEAGPPGSGE------KGERGAAGEPGPH---GPPGVPGSVGPKGSS---GS 672 G G +G+ G P E KG+ G G PGP GPPG PG VGP G G Sbjct: 146 IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205 Query: 673 PGPQGPPGPV--------------GLQGLRGEVGLPGV-----------------KGDKG 701 PG GP GP G++GL G G PG KGDKG Sbjct: 206 PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265 Query: 702 PMGPPGPKG-----------DQGEKGPRGLTGEPGM---------------RGLPGAVGE 735 MG PGP G ++G G GL G+PG RG PG +GE Sbjct: 266 AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325 Query: 736 PGAKGAMGPAGPDGHQGP---------RGEQGLTGMP---GIRGPPGPSGDPGKPGLTGP 783 G KG G GP G +GP +G++G G P G RGP GPSG PG PG G Sbjct: 326 DGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385 Query: 784 QGP--QGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPG----A 837 P +G PG PG G KGE G PGK S G PG PG+ GPPGPPG Sbjct: 386 SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSP-GCAGSPGLPGSPGPPGPPGDIVFR 444 Query: 838 PGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG------PSIPGPPGPRGPPG----EGLP 887 GP G GLPG+ L G PG GP+G PG P IPGPPG G PG +G+P Sbjct: 445 KGPPGDHGLPGY---LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP 501 Query: 888 GPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGH----QGEQGLPGFSTSGSS 943 G G G S +G PG PG PG +GD G G +G +G+ G+PG Sbjct: 502 GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQ 561 Query: 944 SFGLNLQGPPGPP------------------GPQGPKGDKGDPGVPGALGIPSGPSEGGS 985 L G PG P G QGP GD G PG PG G P+GP G Sbjct: 562 PGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAG-PAGPPGYGP 620 Query: 986 SSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPG 1045 + G G PG PGPPG G+ S+ + + G GPPGPPG PG Sbjct: 621 QGEPGLQGTQGVPGAPGPPGEAGPRGEL------------SVSTPVPGPPGPPGPPGHPG 668 Query: 1046 P 1046 P Sbjct: 669 P 669 Score = 329 bits (843), Expect = 1e-89 Identities = 307/896 (34%), Positives = 360/896 (40%), Gaps = 162/896 (18%) Query: 692 GLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQ 751 G G KG+KG GPPG G +G GP GL G G +G PG G G+KG G +G G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 752 GPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGI------KGEPGAP 805 G GL G PG GP G G PG G G QG GLPGT G PGI KG+ GAP Sbjct: 103 G---SPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAP 159 Query: 806 GKIVTSEGSSMLTVPGPPGPPGAMGP---PGPPGAPGPAGPAGLPGHQEVLNLQGPPGPP 862 K E L G PG PGA GP PGPPG PGP GP G PG G GP Sbjct: 160 AK----EEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPG---FFGFPGAMGPR 212 Query: 863 GPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFL--------------SNSETFLSGPP 908 GP+G G + G G RG +GL GPPGPPG+ + + G P Sbjct: 213 GPKGHMGERVIGHKGERGV--KGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEP 270 Query: 909 GPPGPPG--------PKGDQGPPGPRGHQGEQGLPGFSTS----GSSSF-GL-------N 948 GPPGP G KG G PG +G G+ G+PGF S G+ F GL Sbjct: 271 GPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKG 330 Query: 949 LQGPPGPPGPQGP---------KGDKGDPGVPGALGI-----PSGPSEGGSSSTMYVSGP 994 +G GPPG +GP KGD+G PG PG G PSGP S G Sbjct: 331 QKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGL 390 Query: 995 PGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGET 1054 G PG PG GS G+ + + S G+ G PGPPGPPG + G Sbjct: 391 RGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGS--PGLPGSPGPPGPPGDIVFRKGPP 448 Query: 1055 FDYSELASHVVSYLRTSGY-GVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGP 1113 D+ + YL + G GV E L Q Y+ GP G PG Sbjct: 449 GDHG-----LPGYLGSPGIPGV----DGPKGEPGLLCTQ--------CPYIPGPPGLPGL 491 Query: 1114 PGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSL------ 1167 PG G + A ++G+ G PG PG G PG E+ +L Sbjct: 492 PGLHGVKGIPGRQGAAGLKGSPGSPGNTGLP-GFPGFPGAQGDPGLKGEKGETLQPEGQV 550 Query: 1168 -------LRGSEFR-GIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGP 1219 LRG R G+ G PG PG G+PG LS G PG PG Sbjct: 551 GVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELA----LSGEKGDQGPPGDPGSPGS 606 Query: 1220 PGPPGPRGPP-----------GVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPG 1268 PGP GP GPP G G R EL V + + GPPG Sbjct: 607 PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGEL-------SVSTPVPGPPG 659 Query: 1269 PPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGG--------GGAGS 1320 PPGP G PG S + G G G GS Sbjct: 660 PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719 Query: 1321 LGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRV 1380 LG G GE G G G G G A GG G G G + ++ E+ + Sbjct: 720 LGCPGKMGE-PGLPGKPGLP-GAKGEPAVAMPGG--PGTPGFPG-ERGNSGEHGEIGLPG 774 Query: 1381 SESMQRQGLLQGMAYTVQGPPGQPGP---QGPPG--ISKVFSAYSNVTADLMDFFQTYGA 1435 + +G+ +G PGQPGP QGPPG I A Q Sbjct: 775 LPGLPGTPGNEGLD-GPRGDPGQPGPPGEQGPPGRCIEGPRGA------------QGLPG 821 Query: 1436 IQGPPGQKGEMGTPGPKGDRG-----PAGPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 + G GQ+G G GPKGD G +G PG G PG GH+GE G G + Y G Sbjct: 822 LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPG 877 Score = 165 bits (418), Expect = 3e-40 Identities = 187/633 (29%), Positives = 236/633 (37%), Gaps = 139/633 (21%) Query: 912 GPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVP 971 G G KG++G PGP G G++G G P G PGPQGPKG G PG+ Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTG---------------PEGLPGPQGPKGFPGLPGLT 87 Query: 972 GALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYL 1031 G+ G+ G S + G PG PG GP G + G Sbjct: 88 GSKGVRGISGLPGFSGS---PGLPGTPGNTGPYGLVGVPG-------------------C 125 Query: 1032 SGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVL 1091 SG +G G PG PG T Y + G+ + + E+ + + Sbjct: 126 SGSKGEQGFPGLPG--------TLGYPGIPGAA---------GLKGQKGAPAKEEDIELD 168 Query: 1092 QRDDVR-------QYLR--QYLMGPRGPPGPPGASGDGSLLSL--DYAELSSRILSYMSS 1140 + D Q L GP GPPGPPG G + + R++ + Sbjct: 169 AKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGE 228 Query: 1141 SGISIGLPGPPGPPG-----LPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSS 1195 G+ GL GPPGPPG L G L +G +G +G PGPPGP G+PG + S Sbjct: 229 RGVK-GLTGPPGPPGTVIVTLTGPDNRTDLKGEKGD--KGAMGEPGPPGPSGLPGESYGS 285 Query: 1196 ISVEDLSSYLH-TAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENS---DSFRSELI 1251 L G +PG PG G G RG PG+ G + FR Sbjct: 286 EKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTE 345 Query: 1252 SYLTSPDVRSFIVGPPGPPGPQG---------PPGDSRLLSTDASHSRGSSS--SSHSSS 1300 Y T + G PGPPGP+G PPG + RG+ S Sbjct: 346 YYDTYQEKGD--EGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSK 403 Query: 1301 VRRGSSYSSSMSTGG--GGAGSLGAGGAFGEAAGDRGPYGTDI---GPGGGYGAAAEGGM 1355 RG +M T G G AGS G G+ G GP G + GP G +G Sbjct: 404 GERGRPGKDAMGTPGSPGCAGSPGLPGS----PGPPGPPGDIVFRKGPPGDHGLPG---- 455 Query: 1356 YAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKV 1415 Y G+ G+ G D GLL + GPPG PG G G+ + Sbjct: 456 YLGSPGIPGVD---------------GPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGI 500 Query: 1416 ----------FSAYSNVTADLMDFFQTYGAIQGPPGQKGE----------MGTPGPKGDR 1455 S S L F GA QG PG KGE +G PG G R Sbjct: 501 PGRQGAAGLKGSPGSPGNTGLPGFPGFPGA-QGDPGLKGEKGETLQPEGQVGVPGDPGLR 559 Query: 1456 GPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRR 1488 G G G G PG G KG G KG+ +G + Sbjct: 560 GQPGRKGLDGIPGTPGVKGLPGPKGELALSGEK 592 Score = 88.2 bits (217), Expect = 5e-17 Identities = 48/100 (48%), Positives = 56/100 (56%), Gaps = 8/100 (8%) Query: 559 EQENGNLRGSPGPKGDMGSPGPKGDRGFPGT------PGIPGPLGHPGPQGPKGQKGSVG 612 E+ N GS GP G +G GP G RG PGT PG PGP G PG G +G+ G G Sbjct: 1320 EKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPG 1379 Query: 613 DPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEP 652 PG GP G RG+ G G G GP +GEKG +G+ GEP Sbjct: 1380 PPGNLGPCGPRGKPGKDGKPGTPGP--AGEKGNKGSKGEP 1417 Score = 79.0 bits (193), Expect = 3e-14 Identities = 94/293 (32%), Positives = 107/293 (36%), Gaps = 85/293 (29%) Query: 1209 GLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPG 1268 G F G G G G GPPG SP + F GP G Sbjct: 37 GQCFCDGAKGEKGEKGFPGPPG-------------------------SPGQKGF-TGPEG 70 Query: 1269 PPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFG 1328 PGPQGP G G + S VR +S G +GS G G Sbjct: 71 LPGPQGPKG-----------FPGLPGLTGSKGVR-------GISGLPGFSGSPGLPG--- 109 Query: 1329 EAAGDRGPYGTDIGPGGGYGAAAEGGM--YAGNGGLLGADFAGDLDYNELAVRVSESMQR 1386 G+ GPYG +G G G+ E G G G G A L + A E ++ Sbjct: 110 -TPGNTGPYGL-VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIEL 167 Query: 1387 QGL----LQGM--AYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPP 1440 L G + GPPG PGP GPPG FF GA+ GP Sbjct: 168 DAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPP--------------GFFGFPGAM-GPR 212 Query: 1441 GQKGEMG--TPGPKGDRGPAGPPGHPGPPGP-----------RGHKGEKGDKG 1480 G KG MG G KG+RG G G PGPPG KGEKGDKG Sbjct: 213 GPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265 Score = 39.7 bits (91), Expect = 0.022 Identities = 18/40 (45%), Positives = 23/40 (57%) Query: 1443 KGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQ 1482 KG+ G KG++G G PG PG PG +G G +G G Q Sbjct: 36 KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQ 75 Score = 37.4 bits (85), Expect = 0.11 Identities = 16/33 (48%), Positives = 20/33 (60%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGH 598 RG PG G G+PGP G++G G+ G P L H Sbjct: 1390 RGKPGKDGKPGTPGPAGEKGNKGSKGEPESLFH 1422 >gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] Length = 1604 Score = 437 bits (1125), Expect = e-122 Identities = 375/1104 (33%), Positives = 442/1104 (40%), Gaps = 304/1104 (27%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPG---------ME 617 G PG G G PG KG++G G G G G PGP GP G KG+ G+P + Sbjct: 584 GLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQD 643 Query: 618 GPMGQRGREGPMGPRGEAGPPG---------SGEKGERGAAGEPGPHGPPGVPGSVGPKG 668 G + GP G +GE GPPG +GE+G +G G+ G G PG PG+ G G Sbjct: 644 GDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPG 703 Query: 669 SSGSPGPQGPPGPVGLQGLRGEVGLPGVKGD----KGPMGPPGPKGDQGEKGPRGLTGEP 724 SG PG QGP GP G +G G P ++G G G PGPKG+QG +G G G+P Sbjct: 704 LSGEPGVQGPAGPKGEKG-DGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGV-GRPGKP 761 Query: 725 GMRGLPGAVGEPGAKGAMGPAGPDGH--QGPRGEQGLTGMPGI------RGPPGPSGD-- 774 G GLPG G PG KG G GP G QGP+GE G G+PGI RGPPGP+G+ Sbjct: 762 GQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKG 821 Query: 775 ----PGKPGLTGPQGP-----------------QGLPGTPGRPGIKGEPGAPGKI-VTSE 812 PG G TGP GP GL GTPG G +GE G PG+ S+ Sbjct: 822 AQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQ 881 Query: 813 GSSMLTVPGPPGPPGAM-------GPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPP--- 862 G L G PG PG GP GPPG PGP GP G+PG Q V G PG P Sbjct: 882 GD--LIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLT 939 Query: 863 ----------------------GPRGPPG----------PSIPGPPG------------- 877 G R PG IPG PG Sbjct: 940 AELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLER 999 Query: 878 PR----------GPPG----EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGP---KGDQ 920 PR G PG GLPGPPG PG + G PGPPGP GP G Sbjct: 1000 PRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAV 1059 Query: 921 GPPGPRGHQGEQGLPGFS-------TSGSSSFGLNLQGPPGPPGPQGPK------GDKGD 967 G PG G QGE+GL G + G + GPPG PG +G + G+KG+ Sbjct: 1060 GSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYP-GATGPPGLPGIKGERGYTGSAGEKGE 1118 Query: 968 PGVPGALGIPSGP---------------SEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQ 1012 PG PG+ G+P P E G G PGPPGPPG PG + S G Sbjct: 1119 PGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGP 1178 Query: 1013 EIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSG 1072 Q S+ IR SG+ G PGPPGPPG Sbjct: 1179 PGPQ---AEKGSEGIRG-PSGLPGSPGPPGPPG--------------------------- 1207 Query: 1073 YGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSS 1132 I L L D + LR G GP GPPG G Sbjct: 1208 ---------IQGPAGLDGLDGKDGKPGLR----GDPGPAGPPGLMGPP------------ 1242 Query: 1133 RILSYMSSSGISIGLPGP------PGPPGLPGTSYEELLSLLRGSEFR----GIVGPPGP 1182 + +G GLPGP PGPPG G E G + R G VGPPGP Sbjct: 1243 ---GFKGKTG-HPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGP 1298 Query: 1183 PGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAEN 1242 PG PG G S++ ++ GL+ +PG PGPPG PGP G PG GA Sbjct: 1299 PGQPGPAG--ISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPG 1356 Query: 1243 SDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVR 1302 F GPPGP+G PG A+ +G + Sbjct: 1357 KQGFY--------------------GPPGPKGDPG--------AAGQKGQA--------- 1379 Query: 1303 RGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGL 1362 G + M G G +GS+G G G AG+RG G GP G G G+ G + Sbjct: 1380 -GEKGRAGMPGGPGKSGSMGPVGPPG-PAGERGHPGAP-GPSGSPGLP---GVPGSMGDM 1433 Query: 1363 LGADFAGDLDYNELAVRVSESM----QRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSA 1418 + D E+ E M R MA G PG PG G PG + Sbjct: 1434 VNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMA-AAPGRPGPPGKDGAPGRPGAPGS 1492 Query: 1419 YSNVTADLMDFFQTYGAIQGPPGQKGEM-----------GTPGPKGDRGP---------- 1457 + Q ++G PG KGE G PGP G +GP Sbjct: 1493 PGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATG 1552 Query: 1458 ----AGPPGHPGPPGPRGHKGEKG 1477 G PG PGPPGP G G+ G Sbjct: 1553 PMGQQGIPGIPGPPGPMGQPGKAG 1576 Score = 436 bits (1121), Expect = e-122 Identities = 375/1091 (34%), Positives = 448/1091 (41%), Gaps = 224/1091 (20%) Query: 566 RGSPGPKGDMGSPGPKGD-----------------RGFPGTPGIPGPLGHPGPQGPKGQK 608 RG PGP G G G +G+ +G G G GP G PG G KGQK Sbjct: 342 RGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQK 401 Query: 609 GSVGDPGMEGPMGQRGREGP------MGPRGEAGPPGSGEKGERGAAGEPGP---HGPPG 659 G GD G++G G+ GR+G +GP+G+ G PG G G AGEPGP GPPG Sbjct: 402 GEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGF--VGPEGLAGEPGPPGLPGPPG 459 Query: 660 V------------PGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLP---------GVKG 698 + PG G KGSSG PG +GP G G G++GE G P G + Sbjct: 460 IGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQN 519 Query: 699 DKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEP--------GAKGAMGPAGPDGH 750 G G PGPKG+ G+ P G+PG++G+ G GEP GA+ + G G Sbjct: 520 FVGLPGKPGPKGEPGDPVP--ARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGD 577 Query: 751 QGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVT 810 G G GL G+PG G PG G+ G G GP G G PG G GIKG G P + Sbjct: 578 VGSPG-FGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCP 636 Query: 811 SEGS------SMLTVPGPPGPPGAMGPP--GPPGAPGPAGPAGLPGHQEVLNLQGPPGPP 862 + + ++ +PGP G G GPP G PG G AG GL G + G PG P Sbjct: 637 ALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTP 696 Query: 863 GPRGPPG----PSIPGPPGPRGPPGEGL----------------PGPPGPPGSFLSNSET 902 G G PG P + GP GP+G G+G PG PGP G Sbjct: 697 GTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEG-- 754 Query: 903 FLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSG----SSSFGL----NLQGPPG 954 G PG PG PG G QGPPG +G QGE G PG G + GL L GP G Sbjct: 755 --VGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRG 812 Query: 955 PPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPP------------GPPGPPG 1002 PPGP G KG +G PGV GA G P GP G+S VSGPP G PG G Sbjct: 813 PPGPTGEKGAQGSPGVKGATG-PVGPP--GAS----VSGPPGRDGQQGQTGLRGTPGEKG 865 Query: 1003 PPGSISSSGQEIQQYISEYMQSDSI-------------RSYLSGVQGPPGPPGPPGPV-- 1047 P G G+ S Q D I S+ G QGPPG PGPPGP Sbjct: 866 PRGEKGEPGE-----CSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGV 920 Query: 1048 ---------TTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQ 1098 + G+ +EL S + SI + + QR Sbjct: 921 PGLQGVPGNNGLPGQPGLTAELGSLPIE---------QHLLKSICGDCVQG--QRAHPGY 969 Query: 1099 YLRQYLMGPRGPPGPPGASGDGS-LLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLP 1157 + + G +G PG PG LSL+ +G PG PGPPGLP Sbjct: 970 LVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLP 1029 Query: 1158 GTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLS---FIP 1214 G EE +RGS GPPGP GPPG PG V S + L GL+ P Sbjct: 1030 GQRGEEGPPGMRGSP-----GPPGPIGPPGFPGAV-GSPGLPGLQGERGLTGLTGDKGEP 1083 Query: 1215 GPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGP----- 1269 GPPG PG PG GPPG+ G S + E P + GPPGP Sbjct: 1084 GPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGE-----PGPPGSEGLPGPPGPAGPRG 1138 Query: 1270 ----------------------PGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSY 1307 PGP GPPG + + G + S +R S Sbjct: 1139 ERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPG--PPGPQAEKGSEGIRGPSGL 1196 Query: 1308 SSSMSTGG-----GGAGSLGAGGAFGEAA--GDRGPYGTD--IGPGGGYGAAAEGGMYAG 1358 S G G AG G G G+ GD GP G +GP G G G+ G Sbjct: 1197 PGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGL-PG 1255 Query: 1359 NGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKV-FS 1417 G G A +M QG + GPPG PG GP GIS V Sbjct: 1256 PKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHV--GPPGPPGQPGPAGISAVGLK 1313 Query: 1418 AYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKG 1477 T + + G PGQ G G PGP G+ G G G GPPG +G G G Sbjct: 1314 GDRGATGE--------RGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPG 1365 Query: 1478 DKGDQVYAGRR 1488 KGD AG++ Sbjct: 1366 PKGDPGAAGQK 1376 Score = 435 bits (1118), Expect = e-121 Identities = 368/1083 (33%), Positives = 436/1083 (40%), Gaps = 295/1083 (27%) Query: 563 GNLRGSPGPKGDMGS---PGPKGDRGFPGTPGIPGP------------------LGHPGP 601 G+ G PGPKGD GS PG +G G PG PG+ G +G PG Sbjct: 467 GDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGK 526 Query: 602 QGPKGQKG----SVGDPGMEGPMGQRGRE--------------GPMGPRGEAGPPGSGEK 643 GPKG+ G + GDPG++G G++G G G+ G PG G Sbjct: 527 PGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLP 586 Query: 644 GERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGE------------- 690 G G AG PG G G G GP +GSPGP GP GP G++G +GE Sbjct: 587 GLPGRAGVPGLKGEKGNFGEAGP---AGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQD 643 Query: 691 -----VGLPGVKGDKGPMGPP--------GPKGDQGEKGPRGLTGEPGMRGLPGAVGEPG 737 V LPG G+KG GPP G G++G KG +G G PG G PG G PG Sbjct: 644 GDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPG 703 Query: 738 AKGAMGPAGPDGHQGPRGEQGLTGMPGIRGP-PGPSGDPGKPGLTGPQGPQGL--PGTPG 794 G G GP G +G +G+ G T P ++G +G PG+PG G QGP+G+ PG PG Sbjct: 704 LSGEPGVQGPAGPKGEKGD-GCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPG 762 Query: 795 RPGIKGEPGAPG-KIVTSE-GSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEV 852 +PG+ G G PG K V E G V GP G PGA G PG G PGP GP G G + Sbjct: 763 QPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGA 822 Query: 853 LNLQGPPGPPGPRGPPGPSIPGPPGP---------RGPPGEGLP---------------- 887 G G GP GPPG S+ GPPG RG PGE P Sbjct: 823 QGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQG 882 Query: 888 -----GPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPG----FS 938 G PG PG ++ +S + GP GPPG PGP G G PG +G G GLPG + Sbjct: 883 DLIFSGMPGAPGLWMGSS--WQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTA 940 Query: 939 TSGS---------SSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGI------------P 977 GS S G +QG PG KG+KGD G+PG G+ P Sbjct: 941 ELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERP 1000 Query: 978 SGPSEGGSSS--TMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQ 1035 G +S G PG PGPPG PG G G++ Sbjct: 1001 RAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGP-------------------PGMR 1041 Query: 1036 GPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFS---SSISSEDILAVLQ 1092 G PGPPGP GP G+ ++ S + E L L Sbjct: 1042 GSPGPPGPIGP------------------------PGFPGAVGSPGLPGLQGERGLTGLT 1077 Query: 1093 RDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGI--------S 1144 D GP G PG PGA+G L + Y S+G S Sbjct: 1078 GDKGEP-------GPPGQPGYPGATGPPGLPGIKGER------GYTGSAGEKGEPGPPGS 1124 Query: 1145 IGLPGPPGPPGLPGTSYEELLSLLRGSE-FRGIVGPPGPPGPPGIPGNVWSSISVEDLSS 1203 GLPGPPGP G G + S +G + F+G G PGPPGPPG PG V S + Sbjct: 1125 EGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAE 1184 Query: 1204 YLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFI 1263 G I GP G PG PGP GPPG+ G + D P +R Sbjct: 1185 ----KGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDG----------KPGLRG-D 1229 Query: 1264 VGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGA 1323 GP GPPG GPPG +G + G G GS G Sbjct: 1230 PGPAGPPGLMGPPG-----------FKGKTG-------HPGLPGPKGDCGKPGPPGSTGR 1271 Query: 1324 GGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSES 1383 GA GE G GP G GP G G G G G+ GD R + Sbjct: 1272 PGAEGE-PGAMGPQGRP-GPPGHVGPPGPPGQ-PGPAGISAVGLKGD--------RGATG 1320 Query: 1384 MQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAI--QGPPG 1441 + L G GPPG PGP G PG T GA +GPPG Sbjct: 1321 ERGLAGLPGQ----PGPPGHPGPPGEPG--------------------TDGAAGKEGPPG 1356 Query: 1442 QKGEMGTPGPKGDRGPA------------------------GPPGHPGPPGPRGHKGEKG 1477 ++G G PGPKGD G A GP G PGP G RGH G G Sbjct: 1357 KQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPG 1416 Query: 1478 DKG 1480 G Sbjct: 1417 PSG 1419 Score = 429 bits (1104), Expect = e-120 Identities = 370/1085 (34%), Positives = 435/1085 (40%), Gaps = 279/1085 (25%) Query: 567 GSPGPKGDMGSP-GPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGS--------------- 610 G PG GD G P GPKGD+G G PG GP G PG G KG+KG Sbjct: 461 GLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNF 520 Query: 611 VGDPGMEGPMGQRGREGPMGPRGEAGPPG-SGEKGE-----------------RGAAGE- 651 VG PG GP G+ G P+ RG+ G G GEKGE GA+G+ Sbjct: 521 VGLPGKPGPKGEPG--DPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDV 578 Query: 652 -------PGPHGPPGVPGSVGPKGS------SGSPGPQGPPGPVGLQGLRGE-------- 690 PG G GVPG G KG+ +GSPGP GP GP G++G +GE Sbjct: 579 GSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPAL 638 Query: 691 ----------VGLPGVKGDKGPMGPPG--------PKGDQGEKGPRGLTGEPGMRGLPGA 732 V LPG G+KG GPPG G++G KG +G G PG G PG Sbjct: 639 SNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGT 698 Query: 733 VGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGP-PGPSGDPGKPGLTGPQGPQGL-- 789 G PG G G GP G +G +G+ G T P ++G +G PG+PG G QGP+G+ Sbjct: 699 TGRPGLSGEPGVQGPAGPKGEKGD-GCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGR 757 Query: 790 PGTPGRPGIKGEPGAPG-KIVTSE-GSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLP 847 PG PG+PG+ G G PG K V E G V GP G PGA G PG G PGP GP G Sbjct: 758 PGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPT 817 Query: 848 GHQEVLNLQGPPGPPGPRGPPGPSIPGPPGP---------RGPPGEGLP----------- 887 G + G G GP GPPG S+ GPPG RG PGE P Sbjct: 818 GEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECS 877 Query: 888 ----------GPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPG- 936 G PG PG ++ +S + GP GPPG PGP G G PG +G G GLPG Sbjct: 878 CPSQGDLIFSGMPGAPGLWMGSS--WQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQ 935 Query: 937 ---FSTSGS---------SSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGI-------- 976 + GS S G +QG PG KG+KGD G+PG G+ Sbjct: 936 PGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFL 995 Query: 977 ----PSGPSEGGSSSTMYVS--GPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSY 1030 P G +S G PG PGPPG PG G Sbjct: 996 SLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPP----------------- 1038 Query: 1031 LSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSI---SSEDI 1087 G++G PGPPGP GP G+ ++ S + E Sbjct: 1039 --GMRGSPGPPGPIGP------------------------PGFPGAVGSPGLPGLQGERG 1072 Query: 1088 LAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGI---- 1143 L L D GP G PG PGA+G L + Y S+G Sbjct: 1073 LTGLTGDKGEP-------GPPGQPGYPGATGPPGLPGIKGER------GYTGSAGEKGEP 1119 Query: 1144 ----SIGLPGPPGPPGLPGTSYEELLSLLRGSE-FRGIVGPPGPPGPPGIPGNVWSSISV 1198 S GLPGPPGP G G + S +G + F+G G PGPPGPPG PG V S Sbjct: 1120 GPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPP 1179 Query: 1199 EDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPD 1258 + G I GP G PG PGP GPPG+ G + D P Sbjct: 1180 GPQAE----KGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDG----------KPG 1225 Query: 1259 VRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGA 1318 +R GP GPPG GPPG + H G G Sbjct: 1226 LRGD-PGPAGPPGLMGPPGFK-------------GKTGHP-----GLPGPKGDCGKPGPP 1266 Query: 1319 GSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAV 1378 GS G GA GE G GP G GP G G G G G+ GD Sbjct: 1267 GSTGRPGAEGEP-GAMGPQGRP-GPPGHVGPPGPPGQ-PGPAGISAVGLKGD-------- 1315 Query: 1379 RVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYG---- 1434 R + + L G GPPG PGP G PG +A F+ G Sbjct: 1316 RGATGERGLAGLPGQP----GPPGHPGPPGEPGTDG--AAGKEGPPGKQGFYGPPGPKGD 1369 Query: 1435 ----------------AIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGD 1478 + G PG+ G MG GP G G G PG PGP G G G G Sbjct: 1370 PGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGS 1429 Query: 1479 KGDQV 1483 GD V Sbjct: 1430 MGDMV 1434 Score = 412 bits (1058), Expect = e-114 Identities = 301/844 (35%), Positives = 361/844 (42%), Gaps = 190/844 (22%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGP--MGQR 623 RG GP+G+ G+PG G +G PG G PGP G G QG G KG+ G G G G Sbjct: 787 RGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPP 846 Query: 624 GREGPMGPRGEAGPPGSGEKGERGAAGEPGP-----------HGPPGVPG-------SVG 665 GR+G G G G P GEKG RG GEPG G PG PG G Sbjct: 847 GRDGQQGQTGLRGTP--GEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPG 904 Query: 666 PKGSSGSPGPQGPPGPVGLQGLRGEVGLPG--------------------VKGD--KGPM 703 P+G G PGP GPPG GLQG+ G GLPG + GD +G Sbjct: 905 PQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQR 964 Query: 704 GPPGPKGDQGEKGPRGLTGEPGM------------------RGLPGAVGEPGAKGAMGPA 745 PG ++GEKG +G+ G PG+ RG + G+PG G+ G Sbjct: 965 AHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARG-DNSEGDPGCVGSPGLP 1023 Query: 746 GPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAP 805 GP G G RGE+G GM G GPPGP G PG PG G G GL G G G+ G+ G P Sbjct: 1024 GPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEP 1083 Query: 806 GKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGA------PGPAGPAGLPGHQEVLNLQGPP 859 G PG PG PGA GPPG PG G AG G PG L GPP Sbjct: 1084 GP------------PGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPP 1131 Query: 860 GPPGPRGPPG----------------PSIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSET 902 GP GPRG G P PGPPGP G PG+ G PGPPGP S Sbjct: 1132 GPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIR 1191 Query: 903 FLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPP------GPP 956 SG PG PGPPGP G QGP G G G+ G PG + L GPP G P Sbjct: 1192 GPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHP 1251 Query: 957 GPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQ 1016 G GPKGD G PG PG+ G P E G+ GPPG GPPGPPG +G I Sbjct: 1252 GLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAG--ISA 1309 Query: 1017 YISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVS 1076 + + + L+G+ G PGPPG PGP GE Sbjct: 1310 VGLKGDRGATGERGLAGLPGQPGPPGHPGP----PGE----------------------- 1342 Query: 1077 LFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILS 1136 D A + +Q GP GP G PGA+G + + + Sbjct: 1343 ------PGTDGAAGKEGPPGKQ----GFYGPPGPKGDPGAAG-------QKGQAGEKGRA 1385 Query: 1137 YMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSI 1196 M G GP GPPG G RG G GP G PG PG+PG++ + Sbjct: 1386 GMPGGPGKSGSMGPVGPPGPAGE---------RGHP--GAPGPSGSPGLPGVPGSMGDMV 1434 Query: 1197 SVEDLSSYL--------------HTAGLSF------IPGPPGPPGP------PGPRGPPG 1230 + +++ ++ +T+ + F PG PGPPG PG G PG Sbjct: 1435 NYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPG 1494 Query: 1231 VSGALATYAAENSDSFRSELISYLTSPDVRSFIVGP---PGPPGPQGPPGDSRLLSTDAS 1287 + G + + R + D+ I G PGPPGPQGPPG ++ +T Sbjct: 1495 LPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATGPM 1554 Query: 1288 HSRG 1291 +G Sbjct: 1555 GQQG 1558 Score = 402 bits (1032), Expect = e-111 Identities = 262/702 (37%), Positives = 323/702 (46%), Gaps = 111/702 (15%) Query: 543 DSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKG---DRGFPGTPGIPGPLGHP 599 D+ + ++ + + E N G PG G G PGP G RG G PG+ G G P Sbjct: 988 DNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPP 1047 Query: 600 GPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPG 659 GP GP G G+VG PG+ G G+RG G G +GE GPPG G PG GPPG Sbjct: 1048 GPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQ--------PGYPGATGPPG 1099 Query: 660 VPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRG 719 +PG G +G +GS G +G PGP G +GL PG G GP G GP+G+ GEKG +G Sbjct: 1100 LPGIKGERGYTGSAGEKGEPGPPGSEGL------PGPPGPAGPRGERGPQGNSGEKGDQG 1153 Query: 720 LTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPG 779 G+PG G PG G PG G+ GP GP +G G +G +G+PG GPPGP PG Sbjct: 1154 FQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGP------PG 1207 Query: 780 LTGPQGPQGLPGTPGRPGIKGEPGA---PGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPG 836 + GP G GL G G+PG++G+PG PG + PG PGP G G PGPPG Sbjct: 1208 IQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPG 1267 Query: 837 APGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSF 896 + G G G PG + QG PGPPG GPPGP PG PGP G GL G G G Sbjct: 1268 STGRPGAEGEPG---AMGPQGRPGPPGHVGPPGP--PGQPGPAGISAVGLKGDRGATG-- 1320 Query: 897 LSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPP 956 E L+G PG PGPPG G G PG G G++G PG GPPGP Sbjct: 1321 ----ERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQ---------GFYGPPGPK 1367 Query: 957 GPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQ 1016 G G G KG G G G+P GP + GS + GPPGP G G PG+ Sbjct: 1368 GDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPV---GPPGPAGERGHPGA---------- 1414 Query: 1017 YISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVS 1076 G G PG PG PG + G+ +Y E+ + + + Sbjct: 1415 ---------------PGPSGSPGLPGVPGSM----GDMVNYDEIKRFIRQEI------IK 1449 Query: 1077 LFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILS 1136 +F ++ + R G G PG PGA G L E Sbjct: 1450 MFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGRE------- 1502 Query: 1137 YMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSI 1196 G G PG GLPGT E+ + + G+ GPPGP GPPG G + ++ Sbjct: 1503 ---------GRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGY-GKMGAT- 1551 Query: 1197 SVEDLSSYLHTAGLSFIPGPPGP---PGPPGPRGPPGVSGAL 1235 + G+ IPGPPGP PG G P GA+ Sbjct: 1552 ------GPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAM 1587 Score = 393 bits (1010), Expect = e-109 Identities = 326/946 (34%), Positives = 383/946 (40%), Gaps = 249/946 (26%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGI---PGPLGHPGPQGPKGQKGSVGDPGMEGPMG 621 ++G PGP G G GP+G+ G PG PGI PGP G PGP G KG +GS G G GP+G Sbjct: 778 VQGEPGPPG-RGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVG 836 Query: 622 QRGRE--GPMGPRGEAGPPG----SGEKGERGAAGEPGP-----------HGPPGVPG-- 662 G GP G G+ G G GEKG RG GEPG G PG PG Sbjct: 837 PPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLW 896 Query: 663 -----SVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGP------------ 705 GP+G G PGP GPPG GLQG+ G GLPG G +G Sbjct: 897 MGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSIC 956 Query: 706 ----------PGPKGDQGEKGPRGLTGEPGM------------------RGLPGAVGEPG 737 PG ++GEKG +G+ G PG+ RG + G+PG Sbjct: 957 GDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARG-DNSEGDPG 1015 Query: 738 AKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPG 797 G+ G GP G G RGE+G GM G GPPGP G PG PG G G GL G G G Sbjct: 1016 CVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTG 1075 Query: 798 IKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQG 857 + G+ G PG PG PG PGA GPPG PG G G G G + G Sbjct: 1076 LTGDKGEPGP------------PGQPGYPGATGPPGLPGIKGERGYTGSAGEK------G 1117 Query: 858 PPGPPGPRGPPGPSIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGP 916 PGPPG G +PGPPGP GP GE G G G G + GPPGPPG PG Sbjct: 1118 EPGPPGSEG-----LPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGK 1172 Query: 917 KGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGD------------ 964 G GPPGP+ +G +G+ G S S GPPGPPG QGP G Sbjct: 1173 VGSPGPPGPQAEKGSEGIRGPSGLPGSP------GPPGPPGIQGPAGLDGLDGKDGKPGL 1226 Query: 965 KGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQS 1024 +GDPG G G+ P G + + GP G G PGPPGS G E + Sbjct: 1227 RGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEP-------- 1278 Query: 1025 DSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISS 1084 G GP G PGPPG V G + +S + G + Sbjct: 1279 --------GAMGPQGRPGPPGHV----GPPGPPGQPGPAGISAVGLKG------DRGATG 1320 Query: 1085 EDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASG-DGSLLSLDYAELSSRILSYMSSSGI 1143 E LA L GP G PGPPG G DG+ + Sbjct: 1321 ERGLAGLPGQP----------GPPGHPGPPGEPGTDGA--------------AGKEGPPG 1356 Query: 1144 SIGLPGPPGPPGLPGTSYEE-------LLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSI 1196 G GPPGP G PG + ++ + G G +GP GPPGP G G+ Sbjct: 1357 KQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGH----- 1411 Query: 1197 SVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELI----- 1251 PG PGP G PG G PG G + Y E R E+I Sbjct: 1412 -----------------PGAPGPSGSPGLPGVPGSMGDMVNY-DEIKRFIRQEIIKMFDE 1453 Query: 1252 --SYLTS----PDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGS 1305 +Y TS P + G PGPPG G PG R G+ Sbjct: 1454 RMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPG------------------------RPGA 1489 Query: 1306 SYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGA 1365 S + G G G G G G +G G DI G G A E G+ G G G Sbjct: 1490 PGSPGLPGQIGREGRQGLPGVRG-LPGTKGEKG-DI----GIGIAGENGL-PGPPGPQGP 1542 Query: 1366 DFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPG 1411 G + + M +QG + G PG PGP G PG Sbjct: 1543 PGYGKMG-------ATGPMGQQG--------IPGIPGPPGPMGQPG 1573 Score = 299 bits (765), Expect = 2e-80 Identities = 299/1019 (29%), Positives = 377/1019 (36%), Gaps = 240/1019 (23%) Query: 665 GPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRG----- 719 G K + + PP G + + G KG KG G PGP G +GEKG RG Sbjct: 304 GAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVR 363 Query: 720 LTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPG 779 ++ + ++ G GE G GA+GP+G G G +G++G G GI+G PG G G+PG Sbjct: 364 ISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPG 423 Query: 780 ---LTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPP-GPPGAMGPPGPP 835 + GP+G +G PG G G+ GEPG PG + G + PG P GPPG G G Sbjct: 424 EICVIGPKGQKGDPGFVGPEGLAGEPGPPG-LPGPPGIGLPGTPGDPGGPPGPKGDKGSS 482 Query: 836 GAPGPAGPAGLPGHQEV------------------LNLQGPPGPPGPRGPPGPSIP---- 873 G PG GP G PG V N G PG PGP+G PG +P Sbjct: 483 GIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGD 542 Query: 874 ------------------------------GPPGPRGPPGEGLPGPP---------GPPG 894 G G G PG GLPG P G G Sbjct: 543 PGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKG 602 Query: 895 SFLSNSETFLSGPPGPPGPPGPKGDQGP---------------------PGPRGHQGEQG 933 +F GPPGP GP G KG +G PGP G +GE G Sbjct: 603 NFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPG 662 Query: 934 LPGFSTSG----SSSFGL----------------------NLQGPPGPPGPQGPKGDKGD 967 PGF G + GL L G PG GP GPKG+KGD Sbjct: 663 PPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGD 722 Query: 968 ------------------PGVPGALGI--PSGPSEGGSSSTMYVSGPPGPPGPPGPPGSI 1007 PG PG G P G G + G GPPG G G Sbjct: 723 GCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEP 782 Query: 1008 SSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGET-FDYSELASHVVS 1066 G+ +Q Q + L G+QG PGP GPPGP TGE S Sbjct: 783 GPPGRGVQG-----PQGEPGAPGLPGIQGLPGPRGPPGP----TGEKGAQGSPGVKGATG 833 Query: 1067 YLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLD 1126 + G VS + + + GPRG G PG S L Sbjct: 834 PVGPPGASVSGPPGRDGQQGQTGLRGTPGEK--------GPRGEKGEPGECSCPSQGDLI 885 Query: 1127 YAELSSRILSYMSSSGI-----SIGLPGPPGPPGLPGTS--------------------- 1160 ++ + +M SS G+PGPPGPPG+PG Sbjct: 886 FSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSL 945 Query: 1161 --YEELLSLLRGS------------EFRGIVGPPGPPGPPGIPGNVWSSISVE----DLS 1202 + LL + G +G G G PG PG+ +S+E + + Sbjct: 946 PIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEA 1005 Query: 1203 SYLHTAGLSFIPGPPGPPGPP------GPRGPPGVSGALATYAAENSDSFRSEL----IS 1252 ++ G G PG PGPP G GPPG+ G+ F + + Sbjct: 1006 RGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLP 1065 Query: 1253 YLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMS 1312 L + + G G PGP G PG G++ ++ Y+ S Sbjct: 1066 GLQGERGLTGLTGDKGEPGPPGQPG-----------YPGATGPPGLPGIKGERGYTGSAG 1114 Query: 1313 TGG--GGAGSLGAGGAFGEAA--GDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFA 1368 G G GS G G G A G+RGP G G G G + G + G G G F Sbjct: 1115 EKGEPGPPGSEGLPGPPGPAGPRGERGPQGNS-GEKGDQGFQGQPG-FPGPPGPPG--FP 1170 Query: 1369 GDLDY----NELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTA 1424 G + A + SE ++ L G GPPG PG QGP G+ + Sbjct: 1171 GKVGSPGPPGPQAEKGSEGIRGPSGLPGS----PGPPGPPGIQGPAGLDGLDGKDGKPGL 1226 Query: 1425 DLMDFFQTYGAIQGPPGQKGEM---GTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKG 1480 + GPPG KG+ G PGPKGD G GPPG G PG G G G +G Sbjct: 1227 RGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQG 1285 Score = 291 bits (744), Expect = 4e-78 Identities = 272/851 (31%), Positives = 342/851 (40%), Gaps = 151/851 (17%) Query: 695 GVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGP-DGHQGP 753 G + + P GPKG +GE RGL G PG +G GA G + + P P +GP Sbjct: 322 GARDSNVTLAPSGPKGGKGE---RGLPGPPGSKGEKGARGNDCVR--ISPDAPLQCAEGP 376 Query: 754 RGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEG 813 +GE+G +G G G PG +G+ G+ G G G +G+PG PGR G PG+I Sbjct: 377 KGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDG------RPGEICVIGP 430 Query: 814 SSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPS-I 872 PG GP G G PGPPG PGP G GLPG P GPPGP+G G S I Sbjct: 431 KGQKGDPGFVGPEGLAGEPGPPGLPGPPG-IGLPGTPG-----DPGGPPGPKGDKGSSGI 484 Query: 873 PGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGP-RGHQG 930 PG GP G PG+ G+ G G P G PG PGPKG+ G P P RG G Sbjct: 485 PGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPG 544 Query: 931 EQGLPGFS----TSGSSSFGL-NLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGS 985 QG+ G S SS G +L G G G G G PG+PG G+P E G+ Sbjct: 545 IQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGF-GLPGLPGRAGVPGLKGEKGN 603 Query: 986 SSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYIS-EYMQSDSIRSYL----SGVQGPPGP 1040 +G PGPPGP GP G + G+ + + +Q +R SG +G PGP Sbjct: 604 FGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGP 663 Query: 1041 P--GPPGPVTT-----ITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQR 1093 P G PG + G+ D G + +S E Sbjct: 664 PGFGLPGKQGKAGERGLKGQKGDAGNPGD--------PGTPGTTGRPGLSGEP------- 708 Query: 1094 DDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGIS-------IG 1146 G +GP GP G GDG + + G +G Sbjct: 709 ------------GVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVG 756 Query: 1147 LPGPPGPPGLPGTSYEELLSLLRGSEF---RGIVGPPGPPGPPGIPGNVWSSISVEDLSS 1203 PG PG PGLPG L ++G RG+ GP G PG PG+PG Sbjct: 757 RPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPG------------- 803 Query: 1204 YLHTAGLSFIPGPPGPPGPPGPRGP---PGVSGALATYAAENSDSFRSELISYLTSPDVR 1260 + +PGP GPPGP G +G PGV GA T P Sbjct: 804 ------IQGLPGPRGPPGPTGEKGAQGSPGVKGA--------------------TGP--- 834 Query: 1261 SFIVGPPG-----PPGPQGPPGDSRLLSTDASHS-RGSSSSSHSSSVRRGSSYSSSMSTG 1314 VGPPG PPG G G + L T RG S S + +G Sbjct: 835 ---VGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSC---PSQGDLIFSG 888 Query: 1315 GGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFA----GD 1370 GA L G ++ G +GP G GP G G G+ GN GL G G Sbjct: 889 MPGAPGLWMGSSW--QPGPQGPPGIP-GPPGPPGVPGLQGV-PGNNGLPGQPGLTAELGS 944 Query: 1371 LDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGI------SKVFSAYSNVTA 1424 L + ++ QG Y V+ G+ G QG PG+ ++ F + A Sbjct: 945 LPIEQHLLKSICGDCVQGQRAHPGYLVE--KGEKGDQGIPGVPGLDNCAQCFLSLERPRA 1002 Query: 1425 DLMDFFQTYG--AIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQ 1482 + + G G PG G G PG +G+ GP G G PGPPGP G G G G Sbjct: 1003 EEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSP 1062 Query: 1483 VYAGRRRRRSI 1493 G + R + Sbjct: 1063 GLPGLQGERGL 1073 Score = 246 bits (628), Expect = 1e-64 Identities = 163/422 (38%), Positives = 182/422 (43%), Gaps = 108/422 (25%) Query: 565 LRGSPGPKGDMGSPGPKGDRGF------PGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEG 618 L GSPGP G G GP G G PG G PGP G PG GP G KG G PG+ G Sbjct: 1196 LPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPG 1255 Query: 619 PMGQRGREGPMGPRGEAGPPGS-GEKGERGAAGEPGPHGPPGVPGSVGPKGSS------- 670 P G G+ GP G G G G G G +G G PG GPPG PG GP G S Sbjct: 1256 PKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGD 1315 Query: 671 -------------GSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGP 717 G PGP G PGP G G G G G G +G GPPGPKGD G G Sbjct: 1316 RGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQ 1375 Query: 718 RGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQG------PRGEQGLTGMPG------- 764 +G GE G G+PG G+ G+ G +GP GP G +G P G GL G+PG Sbjct: 1376 KGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVN 1435 Query: 765 -------IR-------------------------------GPPGPSGDPGKPGLTGP--- 783 IR GPPG G PG+PG G Sbjct: 1436 YDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGL 1495 Query: 784 ------QGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPG--PP 835 +G QGLPG G PG KGE G G + E G PGPPG GPPG Sbjct: 1496 PGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGEN-------GLPGPPGPQGPPGYGKM 1548 Query: 836 GAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPG------PPGPRGPPGEGLPGP 889 GA GP G G+PG + GPPGP G G G P P + PP + + GP Sbjct: 1549 GATGPMGQQGIPG------IPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKTMKGP 1602 Query: 890 PG 891 G Sbjct: 1603 FG 1604 Score = 97.1 bits (240), Expect = 1e-19 Identities = 60/161 (37%), Positives = 75/161 (46%), Gaps = 10/161 (6%) Query: 546 EELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPK 605 +E + ++ E G PGP G G+PG G PG+PG+PG +G G QG Sbjct: 1452 DERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGA---PGSPGLPGQIGREGRQGLP 1508 Query: 606 GQKGSVGDPGMEGPMGQ--RGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGS 663 G +G G G +G +G G G GP G GPPG G+ GA G G G PG+PG Sbjct: 1509 GVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPG---YGKMGATGPMGQQGIPGIPGP 1565 Query: 664 VGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMG 704 GP G G G P G + E P +K KGP G Sbjct: 1566 PGPMGQPGKAGHCNPSDCFGAMPM--EQQYPPMKTMKGPFG 1604 Score = 41.6 bits (96), Expect = 0.006 Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 23/86 (26%) Query: 1435 AIQGPPGQKGEMGTPGPKGDRG-----------------------PAGPPGHPGPPGPRG 1471 A GP G KGE G PGP G +G P G G G GP G Sbjct: 331 APSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSG 390 Query: 1472 HKGEKGDKGDQVYAGRRRRRSIAVKP 1497 G G+KG + G + + KP Sbjct: 391 LPGSTGEKGQKGEKGDGGIKGVPGKP 416 >gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] Length = 1073 Score = 435 bits (1119), Expect = e-121 Identities = 337/955 (35%), Positives = 397/955 (41%), Gaps = 197/955 (20%) Query: 568 SPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREG 627 +PG K G PG +G+ G PG PG+ G +G G G G+KG G PG G G RG +G Sbjct: 242 APGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKG 301 Query: 628 PMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGP-KGSSGSPGPQGPPGPVGLQG 686 G +GE G PG KG+RG GE GP GPPG+PG+ PG QGP G G G Sbjct: 302 DQGEKGELGLPGL--KGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPG 359 Query: 687 LRGEVGL---PGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMR---GLPGAVGEPGAKG 740 L GE GL PG G +GP GPPG KG +G G G G PG G PG G PG+ G Sbjct: 360 LPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVG 419 Query: 741 AMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKG 800 A G G G G RGE+G G G GP GP GDPG PGL GP G G G PG++G Sbjct: 420 APGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG----KGKDGEPGLRG 475 Query: 801 EPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPG 860 PG PG + T PG PG PG+ G PG G GP GP+G PG + +G PG Sbjct: 476 SPGLPGPLGTKGDRG---APGIPGSPGSRGDPG-IGVAGPPGPSGPPGDKGSPGSRGLPG 531 Query: 861 PPGPRGPPGPS------IPG-------------PPGPRGPPG----EGLPGPPGPPGSFL 897 PGP+GP G PG PPGP G PG +G G PG PG Sbjct: 532 FPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREG 591 Query: 898 SNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPG 957 + + +GPPG PGPPG G QG G RG GE G G QG PG PG Sbjct: 592 TEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGD------------QGHPGVPG 639 Query: 958 PQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQY 1017 GP G+ G PG G G P GS GPPGP GP G PG G+E + Sbjct: 640 FMGPPGNPGPPGADGIAGAAGPPGIQGSPGK---EGPPGPQGPSGLPGIPGEEGKEGRDG 696 Query: 1018 ISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSL 1077 + ++ G+ GP G GPPG G T D S SG Sbjct: 697 -KPGPPGEPGKAGEPGLPGPEGARGPPG----FKGHTGD-----SGAPGPRGESGAMGLP 746 Query: 1078 FSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSY 1137 + +D D Q GPRGPPG G+ G Sbjct: 747 GQEGLPGKD-------GDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGE 799 Query: 1138 MSSSGIS--IGLPGPPGPP---------GLPGTSYEELLSLLRGSE-FRGIVGPP---GP 1182 S G+ +G GPPG P G+PG E RG +G GPP G Sbjct: 800 NGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQ 859 Query: 1183 PGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSG------ALA 1236 PG PGIPG+ + + + GL GP GPPGPPG G PG+ G L Sbjct: 860 PGDPGIPGH-------KGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLR 912 Query: 1237 TYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSS 1296 E ++YL + +++ G PGP GPPG L Sbjct: 913 RLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGL--------------- 957 Query: 1297 HSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMY 1356 G AG +G G G+ G GP G IGP G GA Sbjct: 958 ------------------PGRAGPMGEPGRPGQ-GGLEGPSG-PIGPKGERGA------- 990 Query: 1357 AGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVF 1416 G+ G G G++ GPPG PG G PG +K Sbjct: 991 KGDPGAPGVGLRGEM---------------------------GPPGIPGQPGEPGYAK-- 1021 Query: 1417 SAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRG 1471 G G PGP+G+ GPAG PG PGPPGP G Sbjct: 1022 --------------------------DGLPGIPGPQGETGPAGHPGLPGPPGPPG 1050 Score = 410 bits (1054), Expect = e-114 Identities = 298/793 (37%), Positives = 332/793 (41%), Gaps = 170/793 (21%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLG----------HPGPQGPKGQKGSVGDPG 615 +G G KG++G PG KGDRG G G GP G HP G +G KG GDPG Sbjct: 300 KGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPG 359 Query: 616 MEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGP 675 + G G +GR G +GP+G GPPG+ KG+ GA G PG G PG PG VG G SG PG Sbjct: 360 LPGEPGLQGRPGELGPQGPTGPPGA--KGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGS 417 Query: 676 QGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKG-----PRGLTGEPGMRGLP 730 G PG G G GE G G G++G GP GP+GD G G +G GEPG+RG P Sbjct: 418 VGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSP 477 Query: 731 GAVGEPGAKGAMGPAGPDGHQGPRGEQGL--TGMPGIRGPPGPSGDPGKPGLTG------ 782 G G G KG G G G G RG+ G+ G PG GPPG G PG GL G Sbjct: 478 GLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQG 537 Query: 783 ---------------------------PQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSS 815 P GP GLPG PG G KG PG PG+ T Sbjct: 538 PAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKG 597 Query: 816 MLTVPGPPGPPGAMGPPGPPG---APGPAGPAGLPGHQEVLNLQGPPGPPGP-------- 864 PG PGPPG GP G G A G G G GH V GPPG PGP Sbjct: 598 EAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAG 657 Query: 865 -RGPPG----PSIPGPPGPRGPPG----------EGLPGPPGPPGSFLSNSETFLSGPPG 909 GPPG P GPPGP+GP G EG G PGPPG E L GP G Sbjct: 658 AAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEG 717 Query: 910 PPGPPGPKG---DQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGP----- 961 GPPG KG D G PGPRG G GLPG GP GP GP+GP Sbjct: 718 ARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNG 777 Query: 962 -------------------KGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPG 1002 KG+ G PG+PG LG P E G G PG PG PG Sbjct: 778 SPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPG 837 Query: 1003 ---------------PPGSISSSGQEIQQYISEYMQSDSIRSY--LSGVQGPPGPPGPPG 1045 PPG GQ I + + L G GP GPPGPPG Sbjct: 838 FKGERGDPGIKGDKGPPGG---KGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPG 894 Query: 1046 P--VTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQY 1103 + GE+ L + L G L E LA L + Q Y Sbjct: 895 QPGFPGLRGESPSMETLRRLIQEEL-----GKQL-------ETRLAYL----LAQMPPAY 938 Query: 1104 LMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEE 1163 + +G PGPPG G L + + G GL GP GP G G + Sbjct: 939 MKSSQGRPGPPGPPGKDGLPG------RAGPMGEPGRPGQG-GLEGPSGPIGPKGERGAK 991 Query: 1164 LLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGP- 1222 G RG +GPPG PG PG PG GL IPGP G GP Sbjct: 992 GDPGAPGVGLRGEMGPPGIPGQPGEPGYA--------------KDGLPGIPGPQGETGPA 1037 Query: 1223 -----PGPRGPPG 1230 PGP GPPG Sbjct: 1038 GHPGLPGPPGPPG 1050 Score = 404 bits (1039), Expect = e-112 Identities = 300/864 (34%), Positives = 353/864 (40%), Gaps = 212/864 (24%) Query: 559 EQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPK---GQKGSVGDPG 615 E+ L G PG +G++G G G G G G+PG G PG +G K G+KG +G PG Sbjct: 254 ERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPG 313 Query: 616 MEGPMGQRGREGP----------------------MGPRGEAGPPG-SGEKGERGAAGEP 652 ++G G++G GP GP+GE G PG GE G +G GE Sbjct: 314 LKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGEL 373 Query: 653 GPHGPPGVPGSVGPKGSS---------------GSPGPQGPPGPVGLQGLRGEVGLPGVK 697 GP GP G PG+ G +G+ G+PGP GPPG VG GLRG G G + Sbjct: 374 GPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGER 433 Query: 698 GDKGPM------GPPGPKGDQGEKG-----PRGLTGEPGMRGLPGAVGEPGAKGAMGPAG 746 G+KG GP GP+GD G G +G GEPG+RG PG G G KG G G Sbjct: 434 GEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPG 493 Query: 747 PDGHQGPRGEQGL--TGMPGIRGPPGPSGDPGKPGLTG---------------------- 782 G G RG+ G+ G PG GPPG G PG GL G Sbjct: 494 IPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDI 553 Query: 783 -----------PQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGP 831 P GP GLPG PG G KG PG PG+ T PG PGPPG GP Sbjct: 554 NLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGP 613 Query: 832 PGPP---GAPGPAGPAGLPGHQEVLNLQGPPGPPGP---------RGPPG----PSIPGP 875 G GA G G G GH V GPPG PGP GPPG P GP Sbjct: 614 QGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGP 673 Query: 876 PGPRGPPG----------EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPK---GDQGP 922 PGP+GP G EG G PGPPG E L GP G GPPG K GD G Sbjct: 674 PGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGA 733 Query: 923 PGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSE 982 PGPRG G GLPG GP GP GP+GP G G PG PG G P + Sbjct: 734 PGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQ 793 Query: 983 GGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSY-----LSGVQGP 1037 GS G PG GP GPPG G ++ + + + G +GP Sbjct: 794 KGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGP 853 Query: 1038 PGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVR 1097 PG G PG I G G+ + + E+ Sbjct: 854 PGGKGQPGD-PGIPGH-----------------KGHTGLMGPQGLPGEN----------- 884 Query: 1098 QYLRQYLMGPRGPPGPPGASG----DGSLLSLDY----------AELSSRIL-------- 1135 GP GPPGPPG G G S++ +L +R+ Sbjct: 885 --------GPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPP 936 Query: 1136 SYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSS 1195 +YM SS G PGPPGPPG G G GP G PG PG G Sbjct: 937 AYMKSSQ---GRPGPPGPPGKDG--------------LPGRAGPMGEPGRPGQGG----- 974 Query: 1196 ISVEDLSSYLHTAGLSFIPGPPGPPGP--PGPRGPPGVSGALATYAAENSDSFRSELISY 1253 +E S + G G PG PG G GPPG+ G + + + Sbjct: 975 --LEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPG------QPGEPGYAKDGLPG 1026 Query: 1254 LTSPDVRSFIVGPPGPPGPQGPPG 1277 + P + G PG PGP GPPG Sbjct: 1027 IPGPQGETGPAGHPGLPGPPGPPG 1050 Score = 400 bits (1029), Expect = e-111 Identities = 332/977 (33%), Positives = 395/977 (40%), Gaps = 223/977 (22%) Query: 575 MGSPGPKGDRGFPGTPGI------PGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGP 628 +G+ GP R I PG G G +G+ G G PG+ G +G++G G Sbjct: 219 LGTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGR 278 Query: 629 MGPRGEAGPPGS----GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGL 684 G +GEAG PG+ G +GE+G GE G G PG+ G G KG +G GP G PG L Sbjct: 279 PGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSL 338 Query: 685 ----------QGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVG 734 QG +GE G PG+ G+ G G PG G QG GP G G+ G G PGA G Sbjct: 339 FTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAG 398 Query: 735 EPGAKGAMGPAGPDGHQGPRGEQGLTGMPGI---RGPPGPSGDPGKPGLTGPQGPQGLPG 791 PGA G +G GP G G G GL G PG RG G +G+ G PG GP+G G PG Sbjct: 399 NPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPG 458 Query: 792 TPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQE 851 PG PG KG+ G PG GS PG PGP G G G PG PG G G PG Sbjct: 459 LPGPPG-KGKDGEPGL----RGS-----PGLPGPLGTKGDRGAPGIPGSPGSRGDPGI-- 506 Query: 852 VLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPG-----SFLSNSETFL-- 904 G GPPGP GPPG G PG RG PG PGP GP G S LS + L Sbjct: 507 -----GVAGPPGPSGPPGDK--GSPGSRGLPG--FPGPQGPAGRDGLSSLLSPGDINLLA 557 Query: 905 --------SGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPP 956 GPPG PG PG KGD+G PG G +G +G G + L GPPG Sbjct: 558 KDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPG------LPGPPGIA 611 Query: 957 GPQGP------------KGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPG-------- 996 GPQG KGD+G PGVPG +G P P G+ +GPPG Sbjct: 612 GPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKE 671 Query: 997 -PPGPPGPPGSISSSGQEIQQYISEYM--QSDSIRSYLSGVQGPPGPPGPPGPVTTITGE 1053 PPGP GP G G+E ++ + ++ G+ GP G GPPG G Sbjct: 672 GPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG----FKGH 727 Query: 1054 TFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGP 1113 T D S SG + +D D Q GPRGPPG Sbjct: 728 TGD-----SGAPGPRGESGAMGLPGQEGLPGKD-------GDTGPTGPQGPQGPRGPPGK 775 Query: 1114 PGASGDGSLLSLDYAELSSRILSYMSSSGIS--IGLPGPPGPPG---------LPGTSYE 1162 G+ G S G+ +G GPPG PG +PG E Sbjct: 776 NGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGE 835 Query: 1163 ELLSLLRGSE-FRGIVGPPG---PPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPG 1218 RG +G GPPG PG PGIPG+ + + + GL GP G Sbjct: 836 PGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGH-------KGHTGLMGPQGLPGENGPVG 888 Query: 1219 PPGPPGPRGPPGVSG------ALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGP 1272 PPGPPG G PG+ G L E ++YL + +++ G PGP Sbjct: 889 PPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGP 948 Query: 1273 QGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAG 1332 GPPG L G AG +G G G+ G Sbjct: 949 PGPPGKDGL---------------------------------PGRAGPMGEPGRPGQG-G 974 Query: 1333 DRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQG 1392 GP G IGP G GA G+ G G G++ Sbjct: 975 LEGPSGP-IGPKGERGAK-------GDPGAPGVGLRGEM--------------------- 1005 Query: 1393 MAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPK 1452 GPPG PG G PG +K G PG G G GP Sbjct: 1006 ------GPPGIPGQPGEPGYAK----------------------DGLPGIPGPQGETGPA 1037 Query: 1453 GDRGPAGPPGHPGPPGP 1469 G G GPPG PG P Sbjct: 1038 GHPGLPGPPGPPGQCDP 1054 Score = 394 bits (1012), Expect = e-109 Identities = 279/712 (39%), Positives = 318/712 (44%), Gaps = 138/712 (19%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGR 625 RG G G+ GSPGP G RG PG PG+PGP G G G G +GS G PG G G RG Sbjct: 433 RGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGK-GKDGEPGLRGSPGLPGPLGTKGDRGA 491 Query: 626 EGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQ 685 G G G G PG G AG PGP GPPG GS G +G G PGPQGP G GL Sbjct: 492 PGIPGSPGSRGDPGIG------VAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLS 545 Query: 686 GLR---------------------GEVGLPGVKGDKGPMGPPGPKGDQGEKG---PRGLT 721 L G GLPG KGDKG G PG +G +G+KG P GL Sbjct: 546 SLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLP 605 Query: 722 GEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPG---------IRGPPGPS 772 G PG+ G G+ GE GA G +G G GH G G G G PG GPPG Sbjct: 606 GPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQ 665 Query: 773 GDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPP 832 G PGK G GPQGP GLPG PG G +G G PG PG PGP GA GPP Sbjct: 666 GSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGP---PGEPGKAGEPGLPGPEGARGPP 722 Query: 833 G------PPGAPGPAGPAG---LPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPG 883 G GAPGP G +G LPG + + G GP GP+GP GP GPPG G PG Sbjct: 723 GFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPR--GPPGKNGSPG 780 Query: 884 E-GLPGPPGPPGSFLSNSETFLSGPPG---PPGPPGPKGDQGPPGPRGHQGEQGLPGFST 939 G PGP G PG S E G PG P GPPG G++G PG G G+ G PGF Sbjct: 781 SPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKG 840 Query: 940 SGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGI--PSG-PSEGGSSSTMYVSGPPG 996 ++G GPPG +G GD G PG G G+ P G P E G GPPG Sbjct: 841 ERGDP---GIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPV------GPPG 891 Query: 997 PPGPPGPPG--SISSSGQEIQQYISE-----------YMQSDSIRSYLSGVQGPPGPPGP 1043 PPG PG PG S S + +++ I E Y+ + +Y+ QG PGPPGP Sbjct: 892 PPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGP 951 Query: 1044 PGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQY 1103 PG + G E R G+ S I + Sbjct: 952 PGK-DGLPGRAGPMGEPG-------RPGQGGLEGPSGPIGPK------------------ 985 Query: 1104 LMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEE 1163 G RG G PGA G G + G PG PG PG PG + + Sbjct: 986 --GERGAKGDPGAPGVGLRGEM--------------------GPPGIPGQPGEPGYAKDG 1023 Query: 1164 LLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPG 1215 L + G G PG PGPPG PG D S + A L+ PG Sbjct: 1024 LPGIPGPQGETGPAGHPGLPGPPGPPGQC-------DPSQCAYFASLAARPG 1068 Score = 370 bits (950), Expect = e-102 Identities = 317/979 (32%), Positives = 377/979 (38%), Gaps = 218/979 (22%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDP-GMEGPMGQRG 624 R P D G+ G G RG T +P + P PKG G +GP QR Sbjct: 174 RTDPWENVDQGAQGACG-RG--NTSVLPSSVA-PQCSMPKGTGHEFSAALGTQGPADQRA 229 Query: 625 REGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGL 684 R G + GEPG G G+PG G +G G G G PG Sbjct: 230 -----DARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGE--- 281 Query: 685 QGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGP 744 +GE GLPG G G G G +G++GE G GL G+ G +G G G PG G Sbjct: 282 ---KGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSL 338 Query: 745 AGPD----GHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKG 800 P G QGP+GE+G G+PG G G G+ G G TGP G +G G G PG G Sbjct: 339 FTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAG 398 Query: 801 EPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPG 860 PGAPG + PGP GPPG++G PG G PG G G G +G PG Sbjct: 399 NPGAPGHV---------GAPGPSGPPGSVGAPGLRGTPGKDGERGEKG---AAGEEGSPG 446 Query: 861 PPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQ 920 P GPRG PG PG GPPG+G G PG L G PG PGP G KGD+ Sbjct: 447 PVGPRGDPGA-----PGLPGPPGKGKDGEPG------------LRGSPGLPGPLGTKGDR 489 Query: 921 GPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGP 980 G PG G G +G PG + + GPPGP GP G KG G G+PG G P GP Sbjct: 490 GAPGIPGSPGSRGDPG----------IGVAGPPGPSGPPGDKGSPGSRGLPGFPG-PQGP 538 Query: 981 SEGGSSSTMYVSG-------------PPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSI 1027 + S++ G PPGPPG PG PG G + Sbjct: 539 AGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKG----------VPGKPG 588 Query: 1028 RSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGY-GVSLFSSSISSED 1086 R G +G GPPG PGP + A V G+ GV F Sbjct: 589 REGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGF-------- 640 Query: 1087 ILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIG 1146 MGP G PGPPGA G S G G Sbjct: 641 ------------------MGPPGNPGPPGADGIAGAAGPP---------GIQGSPGKE-G 672 Query: 1147 LPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLH 1206 PGP GP GLPG EE G G G PGPPG PG Sbjct: 673 PPGPQGPSGLPGIPGEE-----------GKEGRDGKPGPPGEPGK--------------- 706 Query: 1207 TAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGP 1266 AG +PGP G GPPG +G G SGA + + L D + GP Sbjct: 707 -AGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQ--EGLPGKDGDTGPTGP 763 Query: 1267 PGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGA 1326 GP GP+GPPG + + + S GS G G G G Sbjct: 764 QGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGV 823 Query: 1327 FGEAA-----------GDRGPYGT--DIGPGGGYGAAAEGGM--YAGNGGLLGAD----- 1366 G+ G+RG G D GP GG G + G+ + G+ GL+G Sbjct: 824 PGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGE 883 Query: 1367 -----------------FAGDLDYNELAVRVSESMQRQGLLQGMAYTV-QGPP------- 1401 G+ E R+ + + L +AY + Q PP Sbjct: 884 NGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQ 943 Query: 1402 GQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPP 1461 G+PGP GPPG G PG+ G MG PG G G GP Sbjct: 944 GRPGPPGPPGKD------------------------GLPGRAGPMGEPGRPGQGGLEGPS 979 Query: 1462 GHPGPPGPRGHKGEKGDKG 1480 G GP G RG KG+ G G Sbjct: 980 GPIGPKGERGAKGDPGAPG 998 Score = 321 bits (823), Expect = 3e-87 Identities = 203/493 (41%), Positives = 237/493 (48%), Gaps = 109/493 (22%) Query: 559 EQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEG 618 +Q + + G GP G+ G PG G G G PGI G G GP GP+G G G PG EG Sbjct: 631 DQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG 690 Query: 619 PMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGP 678 G+ G+ GP G G+AG PG PGP G G PG G G SG+PGP+G Sbjct: 691 KEGRDGKPGPPGEPGKAGEPGL-----------PGPEGARGPPGFKGHTGDSGAPGPRGE 739 Query: 679 PGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGA 738 G +GL G+ GLPG GD GP GP GP QG +GP PG G PG+ GEPG Sbjct: 740 SGAMGLP---GQEGLPGKDGDTGPTGPQGP---QGPRGP------PGKNGSPGSPGEPG- 786 Query: 739 KGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGI 798 P+G G +G +GE G G+PG GP GP PG+PG G G +G+PG PG PG Sbjct: 787 -----PSGTPGQKGSKGENGSPGLPGFLGPRGP---PGEPGEKGVPGKEGVPGKPGEPGF 838 Query: 799 KGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGP 858 KGE G PG + G GPPG G PG PG PG G GL G Q L G Sbjct: 839 KGERGDPG------------IKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQ---GLPGE 883 Query: 859 PGPPGPRGPPGPSIPGPPGPRG-------------------------------PP----- 882 GP GP GPPG PG PG RG PP Sbjct: 884 NGPVGPPGPPGQ--PGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKS 941 Query: 883 GEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGS 942 +G PGPPGPPG G PG PG G +G GP GP+G +G +G PG Sbjct: 942 SQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPG------ 995 Query: 943 SSFGLNLQGPPGPPGPQGPKGDKGD-----PGVPGALGIPSGPSEGGSSSTMYVSGPPGP 997 + G+ L+G GPPG G G+ G PG+PG G +GP +G PG Sbjct: 996 -APGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQG-ETGP-----------AGHPGL 1042 Query: 998 PGPPGPPGSISSS 1010 PGPPGPPG S Sbjct: 1043 PGPPGPPGQCDPS 1055 Score = 295 bits (754), Expect = 3e-79 Identities = 268/845 (31%), Positives = 319/845 (37%), Gaps = 166/845 (19%) Query: 674 GPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPG--PKGDQGE-KGPRGLTGEPGMRGLP 730 GP+ P QG +G G + P PKG E G G R Sbjct: 172 GPRTDPWENVDQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRADA 231 Query: 731 GAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLP 790 A AK A G +G G RGE GL G PG+RG G G G+PG +G GLP Sbjct: 232 RASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPG---EKGEAGLP 288 Query: 791 GTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQ 850 G PG PG++GE G G+ G G PG G G G GPAGP GLPG Sbjct: 289 GAPGFPGVRGEKGDQGE------------KGELGLPGLKGDRGEKGEAGPAGPPGLPGTT 336 Query: 851 EVLN----LQGPPGPPGPRGPPGPSIPGPPGPRGPPGE-GLPGPPGPPGSFLSNSETFLS 905 + + G GP G +G PG +PG PG +G PGE G GP GPPG+ Sbjct: 337 SLFTPHPRMPGEQGPKGEKGDPG--LPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAP 394 Query: 906 GPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDK 965 G G PG PG G GP GP G G GL G G G PGP GP+GD Sbjct: 395 GAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDP 454 Query: 966 GDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSD 1025 G PG+PG P G + G + G PG PGP G G + G Sbjct: 455 GAPGLPG----PPGKGKDGEPG---LRGSPGLPGPLGTKGDRGAPG-------------- 493 Query: 1026 SIRSYLSGVQGPPGPPG-----PPGPVTTITGETFDYSELASH-VVSYLRTSGYGVSLFS 1079 + G G G PG PPGP +G D S + + G Sbjct: 494 -----IPGSPGSRGDPGIGVAGPPGP----SGPPGDKGSPGSRGLPGFPGPQGPAGRDGL 544 Query: 1080 SSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMS 1139 SS+ S + +L +D GP G PG PG GD + E + Sbjct: 545 SSLLSPGDINLLAKD----VCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEG----KK 596 Query: 1140 SSGISIGLPGPPGPPGLPGTSYEELLSLLRGSE-------FRGIVGPPGPPGPPGIPGNV 1192 GLPGPPG G G+ E G + G +GPPG PGPPG G Sbjct: 597 GEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIA 656 Query: 1193 WSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELIS 1252 + AG I G PG GPPGP+GP G+ G E D Sbjct: 657 GA-------------AGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRD-------- 695 Query: 1253 YLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHS----RGSSSSSHSSSVRRGSSYS 1308 G PGPPG G G+ L + + +G + S + R G S + Sbjct: 696 ------------GKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPR-GESGA 742 Query: 1309 SSMSTGGGGAGSLGAGGAFGEAA--GDRGPYGTDIGPG-----GGYGAAAEGGMYAGNGG 1361 + G G G G G G RGP G + PG G G + G NG Sbjct: 743 MGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGS 802 Query: 1362 LLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSN 1421 F G +GPPG+PG +G PG V Sbjct: 803 PGLPGFLGP---------------------------RGPPGEPGEKGVPGKEGVPGK--- 832 Query: 1422 VTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGD 1481 G PG KGE G PG KGD+GP G G PG PG GHKG G G Sbjct: 833 ---------------PGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGP 877 Query: 1482 QVYAG 1486 Q G Sbjct: 878 QGLPG 882 Score = 169 bits (428), Expect = 2e-41 Identities = 192/683 (28%), Positives = 233/683 (34%), Gaps = 174/683 (25%) Query: 863 GPRGPPGPSIPGPPGPRGPPGEG----LPGPPGPPGSFLSNSETFLSGPPGPPGP----- 913 GPR P ++ G +G G G LP P S + S G GP Sbjct: 172 GPRTDPWENVD--QGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRA 229 Query: 914 -------------PGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQG 960 PG K G PG RG G G PG L+G G G G Sbjct: 230 DARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPG------------LRGEIGEQGLAG 277 Query: 961 PKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISE 1020 G+KG+ G+PGA G P E G G G G PG G++ Sbjct: 278 RPGEKGEAGLPGAPGFPGVRGEKGDQ---------GEKGELGLPGLKGDRGEK------- 321 Query: 1021 YMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSS 1080 G GP GPPG PG + T E G Sbjct: 322 ------------GEAGPAGPPGLPGTTSLFTPHPRMPGE-----------QGPKGEKGDP 358 Query: 1081 SISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSS 1140 + E L R +GP+GP GPPGA G A + ++ + Sbjct: 359 GLPGEPGLQG----------RPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGA 408 Query: 1141 SGIS-----IGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSS 1195 G S +G PG G PG G E+ + GS G VGP G PG PG+PG Sbjct: 409 PGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSP--GPVGPRGDPGAPGLPGPPGKG 466 Query: 1196 ISVED-------LSSYLHTAGLSFIPGPPGPPG-----------PPGPRGPPGVSGA--- 1234 E L L T G PG PG PG PPGP GPPG G+ Sbjct: 467 KDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGS 526 Query: 1235 --LATYAAENSDSFRSELISYLTSPDVRSFIVG-----PPGPPGPQGPPGDSRLLSTDAS 1287 L + + R L S L+ D+ PPGPPG G PG Sbjct: 527 RGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGK 586 Query: 1288 HSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTD--IGPGG 1345 R + + G ++ G G GA G G+ GD+G G +GP G Sbjct: 587 PGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQK-GDQGHPGVPGFMGPPG 645 Query: 1346 GYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPG 1405 G G+ AG G G +QG PG+ G Sbjct: 646 NPGPPGADGI-AGAAGPPG--------------------------------IQGSPGKEG 672 Query: 1406 PQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPG 1465 P GP G S + I G G++G G PGP G+ G AG PG PG Sbjct: 673 PPGPQGPSGL------------------PGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPG 714 Query: 1466 PPGPRGHKGEKGDKGDQVYAGRR 1488 P G RG G KG GD G R Sbjct: 715 PEGARGPPGFKGHTGDSGAPGPR 737 Score = 116 bits (291), Expect = 1e-25 Identities = 83/232 (35%), Positives = 93/232 (40%), Gaps = 61/232 (26%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMG---- 621 RG PG KGD G PG KG G PG PG G G GPQG G+ G VG PG G G Sbjct: 842 RGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGL 901 Query: 622 ----------------------------------------QRGREGPMGPRGEAGPPGS- 640 +GR GP GP G+ G PG Sbjct: 902 RGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRA 961 Query: 641 ---GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGP--QGPPGPVGLQGLRGEVG--- 692 GE G G G GP GP G G G KG G+PG +G GP G+ G GE G Sbjct: 962 GPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAK 1021 Query: 693 --LPGVKGDKGPMGP------PGPKGDQGEKGPRGLTGEPGMRGLPGAVGEP 736 LPG+ G +G GP PGP G G+ P + PG V P Sbjct: 1022 DGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1073 Score = 82.0 bits (201), Expect = 4e-15 Identities = 117/447 (26%), Positives = 148/447 (33%), Gaps = 110/447 (24%) Query: 1077 LFSSSISSEDILAV-LQRDDVRQYLRQYLMGPRGPP------GPPGASGDG--SLLSLDY 1127 L S + ++L V L+R R+ L L+GPR P G GA G G S+L Sbjct: 144 LVSQAPLDREVLRVCLERSASRESLD--LLGPRTDPWENVDQGAQGACGRGNTSVLPSSV 201 Query: 1128 AELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPG 1187 A S ++G GP S +L+ + + G PG G G Sbjct: 202 APQCSMPKGTGHEFSAALGTQGPADQRADARASC--ILAAKTAPGLKQLNGEPGERGEDG 259 Query: 1188 IPGN--VWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDS 1245 +PG + I + L+ G + +PG PG PG G +G G G L + Sbjct: 260 LPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDR- 318 Query: 1246 FRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGS 1305 G G GP GPPG S H R Sbjct: 319 -------------------GEKGEAGPAGPPGLPGTTSLFTPHPR--------------- 344 Query: 1306 SYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGA 1365 M G G G G GE G +G G ++GP G G G +G A Sbjct: 345 -----MPGEQGPKGEKGDPGLPGEP-GLQGRPG-ELGPQGPTGPPGAKGQEGAHGAPGAA 397 Query: 1366 DFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTAD 1425 G G G PGP GPPG +V A Sbjct: 398 GNPG---------------------------APGHVGAPGPSGPPG---------SVGAP 421 Query: 1426 LMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPG----------------- 1468 + +G G GE G+PGP G RG G PG PGPPG Sbjct: 422 GLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPG 481 Query: 1469 PRGHKGEKGDKGDQVYAGRRRRRSIAV 1495 P G KG++G G G R I V Sbjct: 482 PLGTKGDRGAPGIPGSPGSRGDPGIGV 508 >gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens] Length = 1712 Score = 435 bits (1119), Expect = e-121 Identities = 366/1075 (34%), Positives = 430/1075 (40%), Gaps = 296/1075 (27%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQ------KGSVGDPGMEGP 619 RG+PG G G G +G GFPG GIP GHPG GP+G+ G+ GD G +GP Sbjct: 93 RGAPGVTGPKGDVGARGVSGFPGADGIP---GHPGQGGPRGRPGYDGCNGTQGDSGPQGP 149 Query: 620 MGQRGREGPMGPRGEAGPPGS-------------GEKGERGAAGEPGPHGPPGVPGSVGP 666 G G GP GP+G G G GE GE G G GP G PG G +GP Sbjct: 150 PGSEGFTGPPGPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGP 209 Query: 667 KGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGP------------------ 708 G+ G PGP GPPGP G QG RG +G GVKG+KG +G PGP Sbjct: 210 VGAPGRPGPPGPPGPKGQQGNRG-LGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVT 268 Query: 709 ---------KGDQGE--------KGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQ 751 KG +GE KG G+ G PG+RG PG GE G+ G G G DG+Q Sbjct: 269 FHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQ 328 Query: 752 GPRGEQGLTGMPGIRGPPG-------PS------GDPGKPGLTGPQGPQGLPGTPGRPGI 798 GP G +G G G GPPG PS GDPG PG G G QG PG PG PG Sbjct: 329 GPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGP 388 Query: 799 KG--------EPGAPGKIVTSEGSSMLTVP----GPPGPPGAMGPPGPPGAPGPAGP--- 843 G G PG++ +P GPPGP G GPPGPPG PGP GP Sbjct: 389 PGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGF 448 Query: 844 -AGLPGHQEVLNLQGPPGPPGPRGPPG--------------------PSIPGP------- 875 GL G + G PG PG RGP G P +PGP Sbjct: 449 LFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGIN 508 Query: 876 -----PGPRGPPGE-GLP------------GPPGPPGSFLSNSETFLS----GPPGPPGP 913 G RG PG+ GLP G PGP G+ +S T + G PG PG Sbjct: 509 GEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGA-KGDSRTITTKGERGQPGVPGV 567 Query: 914 PGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGV--P 971 PG KGD G PG G G GLPG G ++GPPG PG G G KG PG P Sbjct: 568 PGMKGDDGSPGRDGLDGFPGLPGPPGDG-------IKGPPGDPGYPGIPGTKGTPGEMGP 620 Query: 972 GALGIPSGPSEGGSSSTMYVSGPP---GPPGPPGPPGSISSSGQEIQQYISEYMQSDSIR 1028 LG+P + G + GPP GPPGP G PG I ++++ + Q Sbjct: 621 PGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCD-TDVKRAVGGDRQEAIQP 679 Query: 1029 SYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDIL 1088 + G +G PG PGPPGP TG LR G+ F+ + Sbjct: 680 GCIGGPKGLPGLPGPPGP----TG------------AKGLR----GIPGFAGADGGP--- 716 Query: 1089 AVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLP 1148 GPRG PG G G + S G ++GLP Sbjct: 717 -----------------GPRGLPGDAGREGFPG---------PPGFIGPRGSKG-AVGLP 749 Query: 1149 GPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTA 1208 GP G PG G+ GP GPPG G+PG V L + Sbjct: 750 GPDGSPGP-----------------IGLPGPDGPPGERGLPGEV--------LGAQPGPR 784 Query: 1209 GLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPG 1268 G + +PG PG G PG RGPPG G+ + G PG Sbjct: 785 GDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPG--------------------LKGQPG 824 Query: 1269 PPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFG 1328 PGP G PG L H + G + G G GA G G Sbjct: 825 LPGPSGQPG---LYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVG 881 Query: 1329 --EAAGDRGPYG--TDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESM 1384 +GDRG G + G G G GM G GL G + +D Sbjct: 882 MKGLSGDRGDAGFTGEQGHPGSPGFKGIDGM-PGTPGLKGDRGSPGMDG----------- 929 Query: 1385 QRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKG 1444 QGM ++G PG PG +G G FF G PG KG Sbjct: 930 -----FQGMP-GLKGRPGFPGSKGEAG-----------------FF-------GIPGLKG 959 Query: 1445 EMGTPGPKGDRGPAGPPGHPGP--PGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP 1497 G PG KG RG GPPG P PG + KGEKGD+G G + I P Sbjct: 960 LAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMP 1014 Score = 433 bits (1114), Expect = e-121 Identities = 368/1081 (34%), Positives = 458/1081 (42%), Gaps = 186/1081 (17%) Query: 565 LRGSPGPKGDMGSPG------------------PKGDRGFPGTPGIP------------- 593 LRG PG G+ GSPG PKG+ G PG PG+P Sbjct: 303 LRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGAR 362 Query: 594 GPLGHPGPQGPKGQKGSVGDPGMEGPMG--------QRGREGPMGPRGEAGPPGSGEK-- 643 G G PG QG G +G GDPG+ GP G +RG G MGP+G G PG Sbjct: 363 GDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYG 422 Query: 644 GERGAAGEPGPHGPPGVPGSVGP----------KGSSGSPGPQGPPGPVGLQGLRGEVG- 692 G G G+ GP GPPG+PG GP KG +G PG G PG G +G +G+ G Sbjct: 423 GPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGE 482 Query: 693 ---------------LPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPG 737 LPG KG G G PG KGD+G+ G GL G PG++G+PG +G PG Sbjct: 483 CRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPG 542 Query: 738 AKGAMGPAGPDGHQGPRGEQGLTGMPGIR---GPPGPSGDPGKPGLTGPQGP--QGLPGT 792 KGA G + +G RG+ G+ G+PG++ G PG G G PGL GP G +G PG Sbjct: 543 PKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGD 602 Query: 793 PGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPG---- 848 PG PGI G G PG+ + G + + G G PG G PGPPG GP GPAG PG Sbjct: 603 PGYPGIPGTKGTPGE-MGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDC 661 Query: 849 -----------HQEVLN---LQGPPGPPGPRGPPGPS-------IP------GPPGPRGP 881 QE + + GP G PG GPPGP+ IP G PGPRG Sbjct: 662 DTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGL 721 Query: 882 PGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTS 940 PG+ G G PGPPG G PGP G PGP G GP GP GE+GLPG Sbjct: 722 PGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGP---PGERGLPG-EVL 777 Query: 941 GSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGP 1000 G+ G PG PG +G GD+G PG G+ G+P P G SG PG GP Sbjct: 778 GAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGP 837 Query: 1001 PGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPV--TTITGETFDYS 1058 PG G + GQE + R L G +G PG G PGPV ++G+ D Sbjct: 838 PGLHGFPGAPGQEGPLGLPGIPG----REGLPGDRGDPGDTGAPGPVGMKGLSGDRGD-- 891 Query: 1059 ELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLR--QYLMGPRGPPGPPGA 1116 + G+ S I L+ D + Q + G +G PG PG+ Sbjct: 892 ------AGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGS 945 Query: 1117 SGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPG--LPG-------TSYEELLSL 1167 G+ + + + + S G PGPPGPP LPG E + L Sbjct: 946 KGEAGFFGIPGLKGLAGEPGFKGSRGD----PGPPGPPPVILPGMKDIKGEKGDEGPMGL 1001 Query: 1168 LRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRG 1227 +GI G PG PG GIPG ++ + + G+ +PG PG GPPG G Sbjct: 1002 KGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITG 1061 Query: 1228 PPGVSGALATYAAENSDSFRSELISYLTSPDVRSFI--VGPPGPPGPQGPPGDSRLLSTD 1285 PG G+ A E+ + D+ I G PG G +G G L Sbjct: 1062 FPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFF 1121 Query: 1286 ASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAA-----GDRGPYGTD 1340 + G + G G G G+ GE G +G G Sbjct: 1122 GEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWP 1181 Query: 1341 IGPG--GGYGAAAEGGMYA-----GNGGLLGADFAGDLDY-------------NELAVRV 1380 PG G G G++ G G G+D GD + N L V Sbjct: 1182 GAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPV 1241 Query: 1381 SESMQRQGLLQGMAYTVQGPPGQPGPQGPPGI---SKVFSAYSNVTADLMDFFQTYGAIQ 1437 Q+ QG A +GPPG PG QG PGI S + A + A + + Y + Sbjct: 1242 GVPGQKGD--QG-APGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGY---R 1295 Query: 1438 GPPGQKGEMGTPGPKGDRGPAGPPGHPGP------------PGPRGHKGEKGDKGDQVYA 1485 GPPG G PG KGD G G PG PG PG G GEKG +G+Q + Sbjct: 1296 GPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFM 1355 Query: 1486 G 1486 G Sbjct: 1356 G 1356 Score = 413 bits (1061), Expect = e-115 Identities = 356/1031 (34%), Positives = 426/1031 (41%), Gaps = 192/1031 (18%) Query: 565 LRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKG------------QKGSVG 612 + G PG KGD G PG G GFPG G+PG +G PGP+G KG Q G G Sbjct: 507 INGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPG 566 Query: 613 DPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGP------ 666 PGM+G G GR+G G G GPPG G KG G G PG G G PG +GP Sbjct: 567 VPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLP 626 Query: 667 --KGSSGSPGPQGPPGPVGLQGLRGEVGLPG-----------VKGDKGPMGPPG----PK 709 KG G PG G PGP G G G G PG V GD+ PG PK Sbjct: 627 GLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPK 686 Query: 710 GDQGEKGPRGLTGEPGMRGLPG---AVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIR 766 G G GP G TG G+RG+PG A G PG +G G AG +G GP G G G G Sbjct: 687 GLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAV 746 Query: 767 GPPGPSGDPGKPGLTGPQGPQGLPGTPG-----RPGIKGEPGAPGKIVTSEGSSMLTVPG 821 G PGP G PG GL GP GP G G PG +PG +G+ G PG+ + +PG Sbjct: 747 GLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQ------PGLKGLPG 800 Query: 822 PPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPG------PPGPRGPPG-PSIPG 874 GPPG G G PG PG G GLPG L GPPG PG GP G P IPG Sbjct: 801 DRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPG 860 Query: 875 P---PGPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQG 930 PG RG PG+ G PGP G G + +G G PG PG KG G PG G +G Sbjct: 861 REGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKG 920 Query: 931 EQGLPGFSTSGSSSFGLNLQGPPG---PPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSS 987 ++G PG QG PG PG G KG+ G G+PG G+ P GS Sbjct: 921 DRGSPGMD---------GFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSR- 970 Query: 988 TMYVSGPPGPPGPP-----GPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPG 1042 G PGPPGPP G G E + Y+ + I+ + G+ G G PG Sbjct: 971 -----GDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQG-MPGIPGLSGIPG 1024 Query: 1043 PPGPVTTITGETFDYSELA-SHVVSYLRTSGY-GVSLFSSSISSE-------------DI 1087 PG I G D + + +G G++ F I S +I Sbjct: 1025 LPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEI 1084 Query: 1088 LAVLQRDDVRQYL----RQYLMGPRGPPGPPGASG----DGSLLSLDYAELSSRILSYMS 1139 A D+ + R L G RG G PG G G+ + + ++ + Sbjct: 1085 GATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITG-VTGVQG 1143 Query: 1140 SSGIS--IGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSIS 1197 G+ G PG GPPG G + L G G G PG PG PG+ G Sbjct: 1144 PPGLKGQTGFPGLTGPPGSQGELGR--IGLPGGKGDDGWPGAPGLPGFPGLRG------- 1194 Query: 1198 VEDLSSYLHTAGL-----SFIPGPPGPPGPPGPRGPPGVSGAL---ATYAAENSDSFRSE 1249 + L T G S I G PG PGPPG RG PG + L + D Sbjct: 1195 IRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQ---- 1250 Query: 1250 LISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSY-- 1307 +P R GPPG PG QG PG T S+ G+ + + Y Sbjct: 1251 -----GAPGER----GPPGSPGLQGFPG-----ITPPSNISGAPGDKGAPGIFGLKGYRG 1296 Query: 1308 ------SSSMSTGGGGAGSLGAGGAFGEA--AGDRGPYGTD--IGPGGGYGAAAEGGMYA 1357 S+++ G G+ GA G G AGD GP G G G G E G + Sbjct: 1297 PPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQG-FM 1355 Query: 1358 GNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFS 1417 GN G GA GD R + + G PG PG G PGI+ + Sbjct: 1356 GNTGPTGA--VGD--------RGPKGPKGD----------PGFPGAPGTVGAPGIAGIP- 1394 Query: 1418 AYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKG 1477 Q G G +G G PG G+ GP GPPG PG G G G +G Sbjct: 1395 -------------QKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQG 1441 Query: 1478 DKGDQVYAGRR 1488 G G R Sbjct: 1442 RGGVSAVPGFR 1452 Score = 352 bits (902), Expect = 2e-96 Identities = 311/937 (33%), Positives = 376/937 (40%), Gaps = 165/937 (17%) Query: 621 GQRGREGPMGPRGEAGPPG-------SGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSP 673 G RG+ GP+GP+G GPPG G KG++G G PG GP G VG +G SG P Sbjct: 58 GGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKG---DVGARGVSGFP 114 Query: 674 GPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAV 733 G G PG G G RG G G G +G GP GP G +G GP G G G +G P A+ Sbjct: 115 GADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYAL 174 Query: 734 ---------GEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQ 784 GEPG G +G GP G G G+ G G PG GPPGP GP+ Sbjct: 175 PKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGP---------PGPK 225 Query: 785 GPQGLPGTP--GRPGIKGEPGAPG-KIVTSEGSSMLTVP-----GPPGPPGAMGPPGPPG 836 G QG G G G KG+ G PG + S+ + P P G G G PG Sbjct: 226 GQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPG 285 Query: 837 -----APGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG-PSIPGPPGPRGPPGE-GLPGP 889 G G G PG + L G G PG +G G GP GPRGP GE G PGP Sbjct: 286 IRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGP 345 Query: 890 PGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFST-SGSSSFGLN 948 PG P S + G G PG PG +G+ G G G G G PG S G GL Sbjct: 346 PGLPA--YSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGL- 402 Query: 949 LQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSIS 1008 PG GPKG GDPG+P G P GP GPPGPPG PGPPG Sbjct: 403 -------PGEMGPKGFIGDPGIPALYGGPPGPDG--------KRGPPGPPGLPGPPG--- 444 Query: 1009 SSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGE--TFDYSELASHVVS 1066 ++ R+ G+ G PG GP G GE + E + Sbjct: 445 ------PDGFLFGLKGAKGRAGFPGLPGSPGARGPKG-WKGDAGECRCTEGDEAIKGLPG 497 Query: 1067 YLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLD 1126 G+ + I+ E R D Q+ G +G PG GA G Sbjct: 498 LPGPKGF------AGINGEPGRKG-DRGDPGQHGLPGFPGLKGVPGNIGAPGPKG----- 545 Query: 1127 YAELSSRILSYMSSSGIS--IGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPG 1184 A+ SR ++ G G+PG G G PG + L G GI GPPG PG Sbjct: 546 -AKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPG 604 Query: 1185 PPGIPGNVWS-------SISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPG-VSGALA 1236 PGIPG + + + L G + +PGPPG GPPGP G PG + Sbjct: 605 YPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTD 664 Query: 1237 TYAAENSDSFRSELISYLTSPDVRSFIVGPPGP------------------PGPQGPPGD 1278 A D + + P + GPPGP PGP+G PGD Sbjct: 665 VKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGD 724 Query: 1279 SRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRG--- 1335 + R RGS + + G G +G G G G+RG Sbjct: 725 A---------GREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDG-PPGERGLPG 774 Query: 1336 -PYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMA 1394 G GP G G + G+ GL G D R S+ M L+G Sbjct: 775 EVLGAQPGPRGDAGVPGQPGL----KGLPG-------DRGPPGFRGSQGMPGMPGLKGQP 823 Query: 1395 YTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGD 1454 + GP GQPG GPPG+ G PGQ+G +G PG G Sbjct: 824 -GLPGPSGQPGLYGPPGLH---------------------GFPGAPGQEGPLGLPGIPGR 861 Query: 1455 R---GPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRR 1488 G G PG G PGP G KG GD+GD + G + Sbjct: 862 EGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQ 898 Score = 343 bits (880), Expect = 7e-94 Identities = 273/805 (33%), Positives = 326/805 (40%), Gaps = 235/805 (29%) Query: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGRE 626 G PGP G G GP G GFPG PG GPLG PG G +G G GDPG G G G + Sbjct: 824 GLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMK 883 Query: 627 GPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGP----- 681 G G RG+AG +GE+G G+ G G G PG PG G +GS G G QG PG Sbjct: 884 GLSGDRGDAG--FTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPG 941 Query: 682 ----------VGLQGLRGEVGLPGVKGDKGPMGPPGP-----------KGDQGEKGPRGL 720 G+ GL+G G PG KG +G GPPGP KG++G++GP GL Sbjct: 942 FPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGL 1001 Query: 721 TGEPGMRGLPGAVGEPGAKGAMGPAGPDGH-QGPRGEQGLTGMPGIRGPPGPSGDPGKPG 779 G G +G+ G G PG G G G GH +G +G+ G+ G+PG+ G PG +G PG G Sbjct: 1002 KGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITG 1061 Query: 780 LTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPG 839 G G +G G PGR G+ GE GA G + + +PG PG G G G PG G Sbjct: 1062 FPGFIGSRGDKGAPGRAGLYGEIGATGDF--GDIGDTINLPGRPGLKGERGTTGIPGLKG 1119 Query: 840 ------PAGPAGLPGHQEVLNLQGPPGP------PGPRGPPG------------------ 869 G G PG V +QGPPG PG GPPG Sbjct: 1120 FFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDG 1179 Query: 870 ----PSIPGPPGPRGPPG-EGLPGP---PGPPGSFLSNSETFLSGP------------PG 909 P +PG PG RG G GLPG PG PGS + F P PG Sbjct: 1180 WPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPG 1239 Query: 910 PPGPPGPKGDQGPPGPRGHQGEQGLPGF-------STSGSSS-------FGLN-LQGPPG 954 P G PG KGDQG PG RG G GL GF + SG+ FGL +GPPG Sbjct: 1240 PVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPG 1299 Query: 955 PPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEI 1014 PPG G KGD G PGA G P G S GP G PG G PG G+ Sbjct: 1300 PPGSAALPGSKGDTGNPGAPGTPGTKGWAGDS------GPQGRPGVFGLPGEKGPRGE-- 1351 Query: 1015 QQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYG 1074 Q ++ + ++ G +GP G PG PG T+ G Sbjct: 1352 QGFMGNTGPTGAVGD--RGPKGPKGDPGFPGAPGTV--------------------GAPG 1389 Query: 1075 VSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRI 1134 ++ I+ ++ +GP+G GPPGA G+ Sbjct: 1390 IAGIPQKIA----------------VQPGTVGPQGRRGPPGAPGE--------------- 1418 Query: 1135 LSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWS 1194 GP GPPG PG FRG G GP G Sbjct: 1419 -------------MGPQGPPGEPG--------------FRGAPGKAGPQG---------- 1441 Query: 1195 SISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYL 1254 G+S +PG G GP G +GP G GA Sbjct: 1442 ------------RGGVSAVPGFRGDEGPIGHQGPIGQEGA-------------------- 1469 Query: 1255 TSPDVRSFIVGPPGPPGPQGPPGDS 1279 G PG PG G PG S Sbjct: 1470 ---------PGRPGSPGLPGMPGRS 1485 Score = 331 bits (849), Expect = 3e-90 Identities = 224/563 (39%), Positives = 260/563 (46%), Gaps = 83/563 (14%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDP-----GMEGPM 620 +G PG KG G PG KG+ GF G PG+ G G PG +G +G G G P GM+ Sbjct: 931 QGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIK 990 Query: 621 GQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGP----KGSSGSPGPQ 676 G++G EGPMG +G G KG +G G PG G PG+PG G KG G PG Sbjct: 991 GEKGDEGPMGLKGYLGA-----KGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIP 1045 Query: 677 GPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRG----------LTGEPGM 726 G PG G+ G G G PG G +G G PG G GE G G L G PG+ Sbjct: 1046 GLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGL 1105 Query: 727 RGLPGAVGEPGAKGAMGPAGPDGH------------QGPRGEQGLTGMPGIRGPPGPSGD 774 +G G G PG KG G G +G QGP G +G TG PG+ GPPG G+ Sbjct: 1106 KGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGE 1165 Query: 775 PGKPGLTGPQGPQGLPGTPGRPG------IKGEPGAPGK--IVTSEGSSMLTVPGPPGPP 826 G+ GL G +G G PG PG PG I+G G PG S GS + PG PGPP Sbjct: 1166 LGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPP 1225 Query: 827 GAMGPPGPPGA-PGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG----PSIPGPPGPRGP 881 G G PG PGP G G G Q +GPPG PG +G PG +I G PG +G Sbjct: 1226 GERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGA 1285 Query: 882 PG----EGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGF 937 PG +G GPPGPPGS +G PG PG PG KG G GP+G G GLPG Sbjct: 1286 PGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGE 1345 Query: 938 STSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVS----- 992 + GP G G +GPKG KGDPG PGA G P G + V Sbjct: 1346 KGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVG 1405 Query: 993 -----GPPGPPG------PPGPPGSISSSGQEIQQYISEYMQSDSIRSYLS--GVQGP-- 1037 GPPG PG PPG PG + G+ Q R G QGP Sbjct: 1406 PQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIG 1465 Query: 1038 ----------PGPPGPPGPVTTI 1050 PG PG PG +I Sbjct: 1466 QEGAPGRPGSPGLPGMPGRSVSI 1488 Score = 292 bits (748), Expect = 1e-78 Identities = 198/482 (41%), Positives = 220/482 (45%), Gaps = 54/482 (11%) Query: 570 GPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG----- 624 G KGD+G PG G GFPG G PG G PG G +G KG+ G G+ G +G G Sbjct: 1034 GVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDI 1093 Query: 625 --------REGPMGPRGEAGPPGS----GEKGERGAAGEPGPHGPPGVPGSVGPKGSSGS 672 R G G RG G PG GEKG G G PG G GV G G KG +G Sbjct: 1094 GDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGF 1153 Query: 673 PGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGA 732 PG GPPG QG G +GLPG KGD G G PG G G +G RGL G PG +G PG+ Sbjct: 1154 PGLTGPPGS---QGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGS 1210 Query: 733 VGE-----------PGAKGAMGPA----GPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGK 777 G PG +G G A GP G G +G+QG PG RGPPG G G Sbjct: 1211 PGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGA---PGERGPPGSPGLQGF 1267 Query: 778 PGLTGPQGPQGLPGTPGRPGI------KGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMG- 830 PG+T P G PG G PGI +G PG PG PG PG PG G Sbjct: 1268 PGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGW 1327 Query: 831 -----PPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGE- 884 P G PG G G G G Q + GP G G RGP GP G PG G PG Sbjct: 1328 AGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPK--GDPGFPGAPGTV 1385 Query: 885 GLPGPPGPPGSFLSNSETF-LSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSS 943 G PG G P T G GPPG PG G QGPPG G +G G G G Sbjct: 1386 GAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGV 1445 Query: 944 SFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGP 1003 S +G GP G QGP G +G PG PG+ G+P P S + V P P Sbjct: 1446 SAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCP 1505 Query: 1004 PG 1005 G Sbjct: 1506 VG 1507 Score = 215 bits (547), Expect = 3e-55 Identities = 226/783 (28%), Positives = 289/783 (36%), Gaps = 166/783 (21%) Query: 840 PAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPG----------EGLPGP 889 P G G + +G G PGP GP G + GPPG +G PG G PG Sbjct: 41 PCGGRDCSGGCQCYPEKGGRGQPGPVGPQGYN--GPPGLQGFPGLQGRKGDKGERGAPGV 98 Query: 890 PGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPG-FSTSGSSSFGLN 948 GP G + + G G PG PG G +G PG G G QG G GS F Sbjct: 99 TGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGF--- 155 Query: 949 LQGPPGPPGPQGPKGD------------KGDPGVPGALGIPSGPSEGGSSSTMYVSGPPG 996 GPPGP GP+G KG+ +G+PG PG +G P G M G PG Sbjct: 156 -TGPPGPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPG 214 Query: 997 PPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPG-------PVTT 1049 PGPPGPPG GQ+ + + Y + G +G G PGP G P+ Sbjct: 215 RPGPPGPPG---PKGQQGNRGLGFY--------GVKGEKGDVGQPGPNGIPSDTLHPIIA 263 Query: 1050 ITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQY---------- 1099 TG TF + S G+SL ++ +R Y Sbjct: 264 PTGVTFHPDQYKGEKGSEGEPGIRGISLKGEE-------GIMGFPGLRGYPGLSGEKGSP 316 Query: 1100 -------LRQYLMGPRGPPGPPGASGDGSLLSLD-YAELSSRILSYMSSSGI--SIGLPG 1149 L Y GP GP GP G +GD L Y+ S G + G PG Sbjct: 317 GQKGSRGLDGY-QGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPG 375 Query: 1150 PPGPPGLPGTSYEELLSLLRGSEFRGIV-------------------GPP------GPPG 1184 G PG PG LS+ G + RG+ GPP GPPG Sbjct: 376 SQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPG 435 Query: 1185 PPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGP---------------------- 1222 PPG+PG + L AG +PG PG GP Sbjct: 436 PPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGL 495 Query: 1223 ---PGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDS 1279 PGP+G G++G + D + L + P ++ + G G PGP+G GDS Sbjct: 496 PGLPGPKGFAGINGEPGR-KGDRGDPGQHGLPGF---PGLKG-VPGNIGAPGPKGAKGDS 550 Query: 1280 RLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAG--GAFGE-------- 1329 R ++T + GS + G G G G G G+ Sbjct: 551 RTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPG 610 Query: 1330 ---AAGDRGPYGTDI-GPGGGYGAAAEGGMYAGNGGLLG----ADFAGDLDYNELAVRVS 1381 G+ GP G + G G G + G+ G G LG A G +D + R Sbjct: 611 TKGTPGEMGPPGLGLPGLKGQRGFPGDAGL-PGPPGFLGPPGPAGTPGQIDCDTDVKRAV 669 Query: 1382 ESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTAD------------LMDF 1429 +++ + G +G PG PGP GP G + AD + Sbjct: 670 GGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREG 729 Query: 1430 FQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGE-----KGDKGDQVY 1484 F GP G KG +G PGP G GP G PG GPPG RG GE G +GD Sbjct: 730 FPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGV 789 Query: 1485 AGR 1487 G+ Sbjct: 790 PGQ 792 Score = 197 bits (501), Expect = 6e-50 Identities = 134/328 (40%), Positives = 149/328 (45%), Gaps = 46/328 (14%) Query: 529 PAAGADLDKIGLHSDSQEELWMFVRKKLMMEQENG--NLRGSPGPKGDMGSPGPK--GDR 584 P + +L +IGL ++ W G L G PG KG GSPG GD Sbjct: 1160 PGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDP 1219 Query: 585 GFPGTPGIPGPLGH----PGPQGPKGQKGSVGDPGMEGPMGQRGREGPMG---PRGEAGP 637 GFPG PG G G PGP G GQKG G PG GP G G +G G P +G Sbjct: 1220 GFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGA 1279 Query: 638 PGS-------GEKGERGAAGEPGPH---------GPPGVPGSVGPKGSSGSPGPQGPPGP 681 PG G KG RG G PG G PG PG+ G KG +G GPQG PG Sbjct: 1280 PGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGV 1339 Query: 682 VGLQGLRGEVGLPGVKGDKGPMG------PPGPKGDQGEKGPRGLTGEPGMRGLP----- 730 GL G +G G G G+ GP G P GPKGD G G G G PG+ G+P Sbjct: 1340 FGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAV 1399 Query: 731 --------GAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTG 782 G G PGA G MGP GP G G RG G G G G G G G G Sbjct: 1400 QPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIG 1459 Query: 783 PQGPQGLPGTPGRPGIKGEPGAPGKIVT 810 QGP G G PGRPG G PG PG+ V+ Sbjct: 1460 HQGPIGQEGAPGRPGSPGLPGMPGRSVS 1487 Score = 155 bits (392), Expect = 3e-37 Identities = 84/195 (43%), Positives = 102/195 (52%), Gaps = 26/195 (13%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRG- 624 RG PGP G PG KGD G PG PG PG G G GP+G+ G G PG +GP G++G Sbjct: 1295 RGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGF 1354 Query: 625 -----------REGPMGPRGEAGPPGS-GEKGERGAAGEP-------------GPHGPPG 659 GP GP+G+ G PG+ G G G AG P G GPPG Sbjct: 1355 MGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPG 1414 Query: 660 VPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRG 719 PG +GP+G G PG +G PG G QG G +PG +GD+GP+G GP G +G G G Sbjct: 1415 APGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPG 1474 Query: 720 LTGEPGMRGLPGAVG 734 G PGM G ++G Sbjct: 1475 SPGLPGMPGRSVSIG 1489 Score = 87.8 bits (216), Expect = 7e-17 Identities = 59/145 (40%), Positives = 66/145 (45%), Gaps = 23/145 (15%) Query: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIP----------------GPLGHPG---PQGPKG 606 RG GPKGD G PG G G PG GIP GP G PG PQGP G Sbjct: 1367 RGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPG 1426 Query: 607 QKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGS----GEKGERGAAGEPGPHGPPGVPG 662 + G G PG GP G+ G G RG+ GP G G++G G G PG G PG Sbjct: 1427 EPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSV 1486 Query: 663 SVGPKGSSGSPGPQGPPGPVGLQGL 687 S+G S Q P PVG+ L Sbjct: 1487 SIGYLLVKHSQTDQEPMCPVGMNKL 1511 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.135 0.412 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 100,120,574 Number of Sequences: 37866 Number of extensions: 8581665 Number of successful extensions: 356588 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 965 Number of HSP's successfully gapped in prelim test: 2216 Number of HSP's that attempted gapping in prelim test: 37094 Number of HSP's gapped (non-prelim): 58016 length of query: 1497 length of database: 18,247,518 effective HSP length: 115 effective length of query: 1382 effective length of database: 13,892,928 effective search space: 19200026496 effective search space used: 19200026496 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.