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Search of human proteins with 119393899
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|119393899 GLI-Kruppel family member GLI3 [Homo sapiens]
(1580 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|119393899 GLI-Kruppel family member GLI3 [Homo sapiens] 3221 0.0
gi|86991432 GLI-Kruppel family member GLI2 [Homo sapiens] 1177 0.0
gi|4885279 GLI family zinc finger 1 isoform 1 [Homo sapiens] 514 e-145
gi|229892345 GLI family zinc finger 1 isoform 2 [Homo sapiens] 452 e-127
gi|109637784 GLIS family zinc finger 3 isoform a [Homo sapiens] 261 4e-69
gi|109637782 GLIS family zinc finger 3 isoform b [Homo sapiens] 261 4e-69
gi|166706915 GLIS family zinc finger 1 [Homo sapiens] 225 2e-58
gi|110431364 GLIS family zinc finger 2 [Homo sapiens] 194 6e-49
gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens] 185 3e-46
gi|22547201 zinc finger protein of the cerebellum 4 [Homo sapiens] 181 6e-45
gi|4507973 zinc finger protein of the cerebellum 3 [Homo sapiens] 176 2e-43
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens] 175 4e-43
gi|22547182 zinc finger protein of the cerebellum 1 [Homo sapiens] 174 5e-43
gi|116014328 zinc finger protein 143 [Homo sapiens] 134 9e-31
gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens] 126 1e-28
gi|21361146 zinc finger protein 76 (expressed in testis) [Homo s... 121 5e-27
gi|10863995 zinc finger protein 410 [Homo sapiens] 113 2e-24
gi|115583660 zinc finger protein 391 [Homo sapiens] 110 8e-24
gi|156415988 zinc finger and BTB domain containing 7B [Homo sapi... 105 3e-22
gi|239752951 PREDICTED: similar to kruppel-related zinc finger p... 105 3e-22
gi|239752949 PREDICTED: similar to kruppel-related zinc finger p... 105 3e-22
gi|239752947 PREDICTED: similar to kruppel-related zinc finger p... 105 3e-22
gi|147905620 PR domain containing 9 [Homo sapiens] 105 5e-22
gi|4508035 zinc finger protein 7 [Homo sapiens] 104 8e-22
gi|55769561 zinc finger protein 21 isoform 2 [Homo sapiens] 103 1e-21
gi|55769559 zinc finger protein 21 isoform 1 [Homo sapiens] 103 1e-21
gi|122937229 zinc finger protein 629 [Homo sapiens] 103 1e-21
gi|64368880 zinc finger and SCAN domain containing 25 [Homo sapi... 103 1e-21
gi|117956407 zinc finger protein 568 [Homo sapiens] 103 2e-21
gi|65507817 Wilms tumor 1 isoform B [Homo sapiens] 102 3e-21
>gi|119393899 GLI-Kruppel family member GLI3 [Homo sapiens]
Length = 1580
Score = 3221 bits (8350), Expect = 0.0
Identities = 1580/1580 (100%), Positives = 1580/1580 (100%)
Query: 1 MEAQSHSSTTTEKKKVENSIVKCSTRTDVSEKAVASSTTSNEDESPGQTYHRERRNAITM 60
MEAQSHSSTTTEKKKVENSIVKCSTRTDVSEKAVASSTTSNEDESPGQTYHRERRNAITM
Sbjct: 1 MEAQSHSSTTTEKKKVENSIVKCSTRTDVSEKAVASSTTSNEDESPGQTYHRERRNAITM 60
Query: 61 QPQNVQGLSKVSEEPSTSSDERASLIKKEIHGSLPHVAEPSVPYRGTVFAMDPRNGYMEP 120
QPQNVQGLSKVSEEPSTSSDERASLIKKEIHGSLPHVAEPSVPYRGTVFAMDPRNGYMEP
Sbjct: 61 QPQNVQGLSKVSEEPSTSSDERASLIKKEIHGSLPHVAEPSVPYRGTVFAMDPRNGYMEP 120
Query: 121 HYHPPHLFPAFHPPVPIDARHHEGRYHYDPSPIPPLHMTSALSSSPTYPDLPFIRISPHR 180
HYHPPHLFPAFHPPVPIDARHHEGRYHYDPSPIPPLHMTSALSSSPTYPDLPFIRISPHR
Sbjct: 121 HYHPPHLFPAFHPPVPIDARHHEGRYHYDPSPIPPLHMTSALSSSPTYPDLPFIRISPHR 180
Query: 181 NPTAASESPFSPPHPYINPYMDYIRSLHSSPSLSMISATRGLSPTDAPHAGVSPAEYYHQ 240
NPTAASESPFSPPHPYINPYMDYIRSLHSSPSLSMISATRGLSPTDAPHAGVSPAEYYHQ
Sbjct: 181 NPTAASESPFSPPHPYINPYMDYIRSLHSSPSLSMISATRGLSPTDAPHAGVSPAEYYHQ 240
Query: 241 MALLTGQRSPYADIIPSAATAGTGAIHMEYLHAMDSTRFSSPRLSARPSRKRTLSISPLS 300
MALLTGQRSPYADIIPSAATAGTGAIHMEYLHAMDSTRFSSPRLSARPSRKRTLSISPLS
Sbjct: 241 MALLTGQRSPYADIIPSAATAGTGAIHMEYLHAMDSTRFSSPRLSARPSRKRTLSISPLS 300
Query: 301 DHSFDLQTMIRTSPNSLVTILNNSRSSSSASGSYGHLSASAISPALSFTYSSAPVSLHMH 360
DHSFDLQTMIRTSPNSLVTILNNSRSSSSASGSYGHLSASAISPALSFTYSSAPVSLHMH
Sbjct: 301 DHSFDLQTMIRTSPNSLVTILNNSRSSSSASGSYGHLSASAISPALSFTYSSAPVSLHMH 360
Query: 361 QQILSRQQSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLNPVQVSSGPSESSQNKPTSE 420
QQILSRQQSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLNPVQVSSGPSESSQNKPTSE
Sbjct: 361 QQILSRQQSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLNPVQVSSGPSESSQNKPTSE 420
Query: 421 SAVSSTGDPMHNKRSKIKPDEDLPSPGARGQQEQPEGTTLVKEEGDKDESKQEPEVIYET 480
SAVSSTGDPMHNKRSKIKPDEDLPSPGARGQQEQPEGTTLVKEEGDKDESKQEPEVIYET
Sbjct: 421 SAVSSTGDPMHNKRSKIKPDEDLPSPGARGQQEQPEGTTLVKEEGDKDESKQEPEVIYET 480
Query: 481 NCHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRH 540
NCHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRH
Sbjct: 481 NCHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRH 540
Query: 541 TGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRT 600
TGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRT
Sbjct: 541 TGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRT 600
Query: 601 HSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGSHS 660
HSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGSHS
Sbjct: 601 HSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGSHS 660
Query: 661 QSRSPGRPTQGALGEQQDLSNTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPI 720
QSRSPGRPTQGALGEQQDLSNTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPI
Sbjct: 661 QSRSPGRPTQGALGEQQDLSNTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPI 720
Query: 721 SNYSNSGLELPLTDGGSIGDLSAIDETPIMDSTISTATTALALQARRNPAGTKWMEHVKL 780
SNYSNSGLELPLTDGGSIGDLSAIDETPIMDSTISTATTALALQARRNPAGTKWMEHVKL
Sbjct: 721 SNYSNSGLELPLTDGGSIGDLSAIDETPIMDSTISTATTALALQARRNPAGTKWMEHVKL 780
Query: 781 ERLKQVNGMFPRLNPILPPKAPAVSPLIGNGTQSNNTCSLGGPMTLLPGRSDLSGVDVTM 840
ERLKQVNGMFPRLNPILPPKAPAVSPLIGNGTQSNNTCSLGGPMTLLPGRSDLSGVDVTM
Sbjct: 781 ERLKQVNGMFPRLNPILPPKAPAVSPLIGNGTQSNNTCSLGGPMTLLPGRSDLSGVDVTM 840
Query: 841 LNMLNRRDSSASTISSAYLSSRRSSGISPCFSSRRSSEASQAEGRPQNVSVADSYDPIST 900
LNMLNRRDSSASTISSAYLSSRRSSGISPCFSSRRSSEASQAEGRPQNVSVADSYDPIST
Sbjct: 841 LNMLNRRDSSASTISSAYLSSRRSSGISPCFSSRRSSEASQAEGRPQNVSVADSYDPIST 900
Query: 901 DASRRSSEASQSDGLPSLLSLTPAQQYRLKAKYAAATGGPPPTPLPNMERMSLKTRLALL 960
DASRRSSEASQSDGLPSLLSLTPAQQYRLKAKYAAATGGPPPTPLPNMERMSLKTRLALL
Sbjct: 901 DASRRSSEASQSDGLPSLLSLTPAQQYRLKAKYAAATGGPPPTPLPNMERMSLKTRLALL 960
Query: 961 GDALEPGVALPPVHAPRRCSDGGAHGYGRRHLQPHDAPGHGVRRASDPVRTGSEGLALPR 1020
GDALEPGVALPPVHAPRRCSDGGAHGYGRRHLQPHDAPGHGVRRASDPVRTGSEGLALPR
Sbjct: 961 GDALEPGVALPPVHAPRRCSDGGAHGYGRRHLQPHDAPGHGVRRASDPVRTGSEGLALPR 1020
Query: 1021 VPRFSSLSSCNPPAMATSAEKRSLVLQNYTRPEGGQSRNFHSSPCPPSITENVTLESLTM 1080
VPRFSSLSSCNPPAMATSAEKRSLVLQNYTRPEGGQSRNFHSSPCPPSITENVTLESLTM
Sbjct: 1021 VPRFSSLSSCNPPAMATSAEKRSLVLQNYTRPEGGQSRNFHSSPCPPSITENVTLESLTM 1080
Query: 1081 DADANLNDEDFLPDDVVQYLNSQNQAGYEQHFPSALPDDSKVPHGPGDFDAPGLPDSHAG 1140
DADANLNDEDFLPDDVVQYLNSQNQAGYEQHFPSALPDDSKVPHGPGDFDAPGLPDSHAG
Sbjct: 1081 DADANLNDEDFLPDDVVQYLNSQNQAGYEQHFPSALPDDSKVPHGPGDFDAPGLPDSHAG 1140
Query: 1141 QQFHALEQPCPEGSKTDLPIQWNEVSSGSADLSSSKLKCGPRPAVPQTRAFGFCNGMVVH 1200
QQFHALEQPCPEGSKTDLPIQWNEVSSGSADLSSSKLKCGPRPAVPQTRAFGFCNGMVVH
Sbjct: 1141 QQFHALEQPCPEGSKTDLPIQWNEVSSGSADLSSSKLKCGPRPAVPQTRAFGFCNGMVVH 1200
Query: 1201 PQNPLRSGPAGGYQTLGENSNPYGGPEHLMLHNSPGSGTSGNAFHEQPCKAPQYGNCLNR 1260
PQNPLRSGPAGGYQTLGENSNPYGGPEHLMLHNSPGSGTSGNAFHEQPCKAPQYGNCLNR
Sbjct: 1201 PQNPLRSGPAGGYQTLGENSNPYGGPEHLMLHNSPGSGTSGNAFHEQPCKAPQYGNCLNR 1260
Query: 1261 QPVAPGALDGACGAGIQASKLKSTPMQGSGGQLNFGLPVAPNESAGSMVNGMQNQDPVGQ 1320
QPVAPGALDGACGAGIQASKLKSTPMQGSGGQLNFGLPVAPNESAGSMVNGMQNQDPVGQ
Sbjct: 1261 QPVAPGALDGACGAGIQASKLKSTPMQGSGGQLNFGLPVAPNESAGSMVNGMQNQDPVGQ 1320
Query: 1321 GYLAHQLLGDSMQHPGAGRPGQQMLGQISATSHINIYQGPESCLPGAHGMGSQPSSLAVV 1380
GYLAHQLLGDSMQHPGAGRPGQQMLGQISATSHINIYQGPESCLPGAHGMGSQPSSLAVV
Sbjct: 1321 GYLAHQLLGDSMQHPGAGRPGQQMLGQISATSHINIYQGPESCLPGAHGMGSQPSSLAVV 1380
Query: 1381 RGYQPCASFGGSRRQAMPRDSLALQSGQLSDTSQTCRVNGIKMEMKGQPHPLCSNLQNYS 1440
RGYQPCASFGGSRRQAMPRDSLALQSGQLSDTSQTCRVNGIKMEMKGQPHPLCSNLQNYS
Sbjct: 1381 RGYQPCASFGGSRRQAMPRDSLALQSGQLSDTSQTCRVNGIKMEMKGQPHPLCSNLQNYS 1440
Query: 1441 GQFYDQTVGFSQQDTKAGSFSISDASCLLQGTSAKNSELLSPGANQVTSTVDSLDSHDLE 1500
GQFYDQTVGFSQQDTKAGSFSISDASCLLQGTSAKNSELLSPGANQVTSTVDSLDSHDLE
Sbjct: 1441 GQFYDQTVGFSQQDTKAGSFSISDASCLLQGTSAKNSELLSPGANQVTSTVDSLDSHDLE 1500
Query: 1501 GVQIDFDAIIDDGDHSSLMSGALSPSIIQNLSHSSSRLTTPRASLPFPALSMSTTNMAIG 1560
GVQIDFDAIIDDGDHSSLMSGALSPSIIQNLSHSSSRLTTPRASLPFPALSMSTTNMAIG
Sbjct: 1501 GVQIDFDAIIDDGDHSSLMSGALSPSIIQNLSHSSSRLTTPRASLPFPALSMSTTNMAIG 1560
Query: 1561 DMSSLLTSLAEESKFLAVMQ 1580
DMSSLLTSLAEESKFLAVMQ
Sbjct: 1561 DMSSLLTSLAEESKFLAVMQ 1580
>gi|86991432 GLI-Kruppel family member GLI2 [Homo sapiens]
Length = 1586
Score = 1177 bits (3044), Expect = 0.0
Identities = 739/1573 (46%), Positives = 927/1573 (58%), Gaps = 155/1573 (9%)
Query: 124 PPHLFPAFHPPVPIDARHHEGRYHYDPSPIPPLHMTSALSSSPTYPDLPFIRISPHRNPT 183
P HL P FH P+PID RH EGRYHY+P + +H ALS SP D+ IR+SPH P
Sbjct: 51 PQHLLPPFHAPLPIDMRHQEGRYHYEPHSVHGVHGPPALSGSPVISDISLIRLSPH--PA 108
Query: 184 AASESPFSPPHPYINPYMD-YIRSLHSSPSLSMISATRGLSPTDA-------------PH 229
ESPF+ PHPY+NP+M+ Y+RS+HSSP+LSMISA RGLSP D P
Sbjct: 109 GPGESPFNAPHPYVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQEHLKERGLFGLPA 168
Query: 230 AGVSPAEYYHQMALLTGQRSPYADIIPSAATAGTGAIHMEYLHAMDSTRFSSPRLSARPS 289
G +P++YYHQM L+ G +PY D++ + A + +YL+ +D +RFSSPR++ R S
Sbjct: 169 PGTTPSDYYHQMTLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDVSRFSSPRVTPRLS 228
Query: 290 RKRTLSISPLSDHSFDLQTMIRTSPNSLVTILNNSRSSSSASGSYGHLSASAISPALSFT 349
RKR LSISPLSD S DLQ MIRTSPNSLV +NNSRSSS+ASGSYGHLSA A+SPA +F
Sbjct: 229 RKRALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFP 288
Query: 350 YSSAPVSLHMHQQILSRQQSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLNPVQVSSGP 409
+ PV+ +QQILS+Q+ LGSAFGH+PPLI P+PTF Q+P+ P Q+SS
Sbjct: 289 HPINPVA---YQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSINATPTQLSSSS 345
Query: 410 ---SESSQNKPTSESAVSSTGDPMH-NKRSKIKPDEDLPSPGA-----RGQQE------- 453
S+++QNK +SESAVSST +P+ +KRSK+K + + P + +GQ
Sbjct: 346 NCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQGQVSGHGSCGC 405
Query: 454 ----QPEGTTLVKEEGDKDESKQEPEV-IYETNCHWEGCAREFDTQEQLVHHINNDHIHG 508
E +KE+ D+D+ KQE EV IYETNCHWE C +E+DTQEQLVHHINN+HIHG
Sbjct: 406 ALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHG 465
Query: 509 EKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLR 568
EKKEFVCRW C+REQKPFKAQYMLVVHMRRHTGEKPHKCTFEGC+KAYSRLENLKTHLR
Sbjct: 466 EKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLR 525
Query: 569 SHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHV 628
SHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPY+CKIPGCTKRYTDPSSLRKHV
Sbjct: 526 SHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHV 585
Query: 629 KTVHGPEAHVTKKQRGDIHPRPPPPRDSGSHSQSRSPGRPTQGALGEQQDLSNTTSKREE 688
KTVHGP+AHVTKKQR D+H R P +++G PG P E + S+T+ E+
Sbjct: 586 KTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEAGTEPGGP------ESTEASSTSQAVED 639
Query: 689 CLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPISNYSN--SGLELPLTDGGSIGDLSAIDE 746
CL V+ +K E Q SPG QSSCSS+ SP+ + N SG+E+P T GS+GDL+A+D+
Sbjct: 640 CLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALDD 699
Query: 747 TPI-MDSTISTATTALALQARRNPAGTKWMEHVKLERLKQVNGMFPRLNPILPPKAPAVS 805
TP D++ A +A LQ R++ E +K E+LK + P + +
Sbjct: 700 TPPGADTSALAAPSAGGLQLRKHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRNTKLP 759
Query: 806 PLIGNGTQSNNTCSL--GGPMTLLPG--RSDLSGVDVTMLNML-NRRDSSASTISSAYLS 860
PL G+G+ N GGP LLP S+LS +VTML+ L RRDSS ST+SSAY
Sbjct: 760 PLPGSGSILENFSGSGGGGPAGLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSSAYTV 819
Query: 861 SRRSSGISPCFSSRRSSEASQ-AEGRPQNVSVADSYDPISTDASRRSSEASQSDGLPSLL 919
SRRSSGISP FSSRRSSEAS GRP N S ADSYDPISTDASRRSSEASQ G LL
Sbjct: 820 SRRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQCSGGSGLL 879
Query: 920 SLTPAQQYRLKAKYAAATGGPPPTPLPNMERMSLKTRLALLGDALEPGV--ALPPVHAPR 977
+LTPAQQY L+AKYAAATGGPPPTPLP +ERMSL+TRLALL DA E + P PR
Sbjct: 880 NLTPAQQYSLRAKYAAATGGPPPTPLPGLERMSLRTRLALL-DAPERTLPAGCPRPLGPR 938
Query: 978 RCSDGGAHGYGRRHLQ---PHDAPGHGVRRASDPVRTGSEGLALPRVPRFSSLSSCNPPA 1034
R SDG +G+G PH+APG G RRASDPVR + L+LPRV RF S + NP
Sbjct: 939 RGSDGPTYGHGHAGAAPAFPHEAPGGGARRASDPVRR-PDALSLPRVQRFHSTHNVNPGP 997
Query: 1035 MATSAEKRSLVLQNYTRPEGGQSRNFHSSPCPPSITENVTLESLTM-------DADANLN 1087
+ A++R L LQ++ +GG +R + SP PPSI+ENV +E++ +AD L
Sbjct: 998 LPPCADRRGLRLQSHPSTDGGLARGAY-SPRPPSISENVAMEAVAAGVDGAGPEADLGLP 1056
Query: 1088 DEDF-LPDDVVQYLNSQNQAGYEQHFPSALPDDSKVPHGPGDFDAPGL--------PDSH 1138
++D LPDDVVQY+ + ++ P +S +PGL DS+
Sbjct: 1057 EDDLVLPDDVVQYIKAHASGALDEGTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADSN 1116
Query: 1139 AGQQFHALEQPCPEG-------SKTDLPIQWNEVSSGSADLSSSKLKCGPRPAVPQTRAF 1191
G L C G +K ++P+QWNEVSSG+ D +S++K P P
Sbjct: 1117 VGPSAPML-GGCQLGFGAPSSLNKNNMPVQWNEVSSGTVDALASQVKPPPFPQ------- 1168
Query: 1192 GFCNGMVVHPQNPLRSGPAGGYQTLGENSNPYGGPEHLMLHNSPGSGTSGNAFHEQPCKA 1251
+ V Q P G GY G ++P GG + H P SG Q
Sbjct: 1169 ---GNLAVVQQKP-AFGQYPGYSPQGLQASP-GGLDSTQPHLQPRSGAP-----SQGIPR 1218
Query: 1252 PQYGNCLNRQPVAPGALDG--------ACGAGIQASKLKSTPMQGSGGQLNFGLPVAPNE 1303
Y L RQPVA G AC + +L + + G+ Q P
Sbjct: 1219 VNYMQQL-RQPVAGSQCPGMTTTMSPHACYGQVH-PQLSPSTISGALNQFPQSCSNMP-A 1275
Query: 1304 SAGSMVNGMQNQ---DPVGQGYLAHQ-------LLGDSMQHPGAGRPGQQMLGQISATSH 1353
G + + Q + DP G + L G HP P Q ++A+
Sbjct: 1276 KPGHLGHPQQTEVAPDPTTMGNRHRELGVPDSALAGVPPPHPVQSYP--QQSHHLAASMS 1333
Query: 1354 INIYQGPESCLPGAH---------GMGSQPSSLAVVRGYQPCASFGGSRR---------- 1394
Y S LP MG + +V+ P R
Sbjct: 1334 QEGYHQVPSLLPARQPGFMEPQTGPMGVATAGFGLVQPRPPLEPSPTGRHRGVRAVQQQL 1393
Query: 1395 ---QAMPRDSLALQSGQLSDTSQTCRVNGIKMEMKGQPHPL-CSNLQNYSGQFYDQTVGF 1450
+A A+ S Q + + G + QP P ++S +Y +
Sbjct: 1394 AYARATGHAMAAMPSSQETAEAVPKGAMGNMGSVPPQPPPQDAGGAPDHSMLYYYGQIHM 1453
Query: 1451 SQQD---TKAGSFSISDASCLLQGTSAKNSELLSPGANQVTSTVDS-LDSHDLEGVQIDF 1506
+QD GS + S Q + ++S P + + V S +DS LE QIDF
Sbjct: 1454 YEQDGGLENLGSCQVM-RSQPPQPQACQDSIQPQPLPSPGVNQVSSTVDSQLLEAPQIDF 1512
Query: 1507 DAIIDDGDHSSLMSGALSPSIIQNLSHSSSRLTTPRASLPFPALSMSTTNMAIGDMSSLL 1566
DAI+DDGDHSSL SGALSPS++ +LS +SSRLTTPR SL P++ +NMA+GDMSS+L
Sbjct: 1513 DAIMDDGDHSSLFSGALSPSLLHSLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSML 1572
Query: 1567 TSLAEESKFLAVM 1579
TSLAEESKFL +M
Sbjct: 1573 TSLAEESKFLNMM 1585
>gi|4885279 GLI family zinc finger 1 isoform 1 [Homo sapiens]
Length = 1106
Score = 514 bits (1324), Expect = e-145
Identities = 390/1019 (38%), Positives = 501/1019 (49%), Gaps = 230/1019 (22%)
Query: 231 GVSPAEYYHQMALLTGQRSPYADIIPSAATAGTGAIHMEYLHAMDSTRFSSPRLSARPSR 290
G+S + HQ L++G S ++ T G FSSPR + + ++
Sbjct: 34 GLSGPPFCHQANLMSGPHSYGPARETNSCTEGP--------------LFSSPRSAVKLTK 79
Query: 291 KRTLSISPLSDHSFDLQTMIRTSPNSLVTILNNSRSSSSASGSYGHLSASAISPALSFTY 350
KR LSISPLSD S DLQT+IRTSP+SLV +N+ +S GSYGHLS +SP+L F
Sbjct: 80 KRALSISPLSDASLDLQTVIRTSPSSLVAFINS--RCTSPGGSYGHLSIGTMSPSLGF-- 135
Query: 351 SSAPVSLHMHQQILSRQQSLGSAFGHSPPLIHPAPTFPTQ--RPIPGIPTVLNPVQVSSG 408
P ++ HQ+ P+P+F Q P + P S G
Sbjct: 136 ---PAQMN-HQK-------------------GPSPSFGVQPCGPHDSARGGMIPHPQSRG 172
Query: 409 PSESSQNKPTSESAVSSTGDPMHNKRSKIKPDEDLPSPGARGQQEQPEGTTLVKEEGDKD 468
P + Q K S D + K + + D+ SP + G Q+ G +E+ +++
Sbjct: 173 PFPTCQLK--------SELDMLVGKCREEPLEGDMSSPNSTGIQDPLLGMLDGREDLERE 224
Query: 469 ESKQEPEVIYETNCHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFK 528
E K+EPE +YET+C W+GC++EFD+QEQLVHHIN++HIHGE+KEFVC W CSRE +PFK
Sbjct: 225 E-KREPESVYETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFK 283
Query: 529 AQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFS 588
AQYMLVVHMRRHTGEKPHKCTFEGC K+YSRLENLKTHLRSHTGEKPY+CEHEGC+KAFS
Sbjct: 284 AQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFS 343
Query: 589 NASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHP 648
NASDRAKHQNRTHSNEKPYVCK+PGCTKRYTDPSSLRKHVKTVHGP+AHVTK+ RGD P
Sbjct: 344 NASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGD-GP 402
Query: 649 RPPPPRDSGSHSQSRSPGRPTQGALGEQQDLSNTTSKREECLQVKTVKAEKPMTSQPSPG 708
P P S + G P REE + E M QPSPG
Sbjct: 403 LPRAPSISTVEPKREREGGPI----------------REES---RLTVPEGAMKPQPSPG 443
Query: 709 GQSSCSSQQSPISNYSN--SGLELPLTDGGSIGDLSAIDETPIMDSTISTATTALALQAR 766
QSSCSS SP + +N SG+E+ GGS DLS++DE P + A T L+ R
Sbjct: 444 AQSSCSSDHSPAGSAANTDSGVEMTGNAGGSTEDLSSLDEGPCI------AGTGLSTLRR 497
Query: 767 RNPAGTKWMEHVKLERLKQVNGMFPRLNPILPPKAPAVSPLIGNGTQSNNTCSLGGPMTL 826
+E+++L++L Q L PI GT+ SL T
Sbjct: 498 --------LENLRLDQLHQ-------LRPI--------------GTRGLKLPSLSHTGTT 528
Query: 827 LPGRSDLSGVDVTMLNMLNRRDSSASTISSAYLSSRRSSGISPCFSSRRSSEASQAEGRP 886
+ R G V+ L RR SS+S+ISSAY SRRSS SP
Sbjct: 529 VSRR---VGPPVS----LERRSSSSSSISSAYTVSRRSSLASP----------------- 564
Query: 887 QNVSVADSYDPISTDASRRSSEASQSDGLPSLLSLTPAQQYRLKAKYAAAT-GGPPPTPL 945
+ P S +G SL L PAQ Y L+A+YA+A GG PT
Sbjct: 565 --------FPPGS----------PPENGASSLPGLMPAQHYLLRARYASARGGGTSPTAA 606
Query: 946 PNMERMSLKTRLALLGDALEPGVALPPVHAPRRCSDGGAHGYGRRHLQPHDAPGHGV-RR 1004
+++R+ G+ +PP + R P P GV RR
Sbjct: 607 SSLDRIG--------------GLPMPP--------------WRSRAEYPGYNPNAGVTRR 638
Query: 1005 ASDPVRTGSEGLALPRVPRFSSLSSCN-PPAMATSAEKRSLVLQNYTRPEGGQSRNFHSS 1063
ASDP + ++ A RV RF SL + PP +A + L S
Sbjct: 639 ASDPAQ-AADRPAPARVQRFKSLGCVHTPPTVAGGGQNFDPYLPTSV-----------YS 686
Query: 1064 PCPPSITENVTLESLTMDADANLNDE----------DFLPDDVVQYLNSQNQAGYEQHFP 1113
P PPSITEN +++ + + + DF P D + Y + A P
Sbjct: 687 PQPPSITENAAMDARGLQEEPEVGTSMVGSGLNPYMDFPPTDTLGYGGPEGAAAE----P 742
Query: 1114 SALPDDSKVPHGPGDFDAPGLPDSHAGQQFHALEQPCPEGSKTDLPIQ--WNEVSSGSAD 1171
+P GPG P ++ G PCP+ + P Q W E S S
Sbjct: 743 YGARGPGSLPLGPG-------PPTNYG------PNPCPQQASYPDPTQETWGEFPSHSGL 789
Query: 1172 LSSSKLKCGPRPAVPQTRAFGFCNGMVVHPQN--PLRSGPAGGYQTLGENSNPYGGPEH 1228
K G P+ +G + V P+ P+ S G L N++P GP H
Sbjct: 790 YPGPKALGGTYSQCPRLEHYG---QVQVKPEQGCPVGSDSTGLAPCL--NAHPSEGPPH 843
Score = 42.4 bits (98), Expect = 0.004
Identities = 37/98 (37%), Positives = 48/98 (48%), Gaps = 20/98 (20%)
Query: 1479 LLSPGANQVTSTVDSLDSHDLEGVQIDFDAIIDDGDHSSLMSGALSPSIIQNLSHSSSRL 1538
L P QV + +DSLD L+ Q+DF AI+D+ LSP + SS
Sbjct: 1025 LYPPPEGQVCNPLDSLD---LDNTQLDFVAILDEPQ-------GLSPPPSHDQRGSSGH- 1073
Query: 1539 TTPRASLPFPALSMSTTNMAIGDMSSLLTSLAEESKFL 1576
TP S P NMA+G+MS LL SL E++FL
Sbjct: 1074 -TPPPSGP--------PNMAVGNMSVLLRSLPGETEFL 1102
>gi|229892345 GLI family zinc finger 1 isoform 2 [Homo sapiens]
Length = 978
Score = 452 bits (1164), Expect = e-127
Identities = 337/867 (38%), Positives = 428/867 (49%), Gaps = 189/867 (21%)
Query: 383 PAPTFPTQR--PIPGIPTVLNPVQVSSGPSESSQNKPTSESAVSSTGDPMHNKRSKIKPD 440
P+P+F Q P + P S GP + Q K S D + K + +
Sbjct: 17 PSPSFGVQPCGPHDSARGGMIPHPQSRGPFPTCQLK--------SELDMLVGKCREEPLE 68
Query: 441 EDLPSPGARGQQEQPEGTTLVKEEGDKDESKQEPEVIYETNCHWEGCAREFDTQEQLVHH 500
D+ SP + G Q+ G +E+ +++E K+EPE +YET+C W+GC++EFD+QEQLVHH
Sbjct: 69 GDMSSPNSTGIQDPLLGMLDGREDLEREE-KREPESVYETDCRWDGCSQEFDSQEQLVHH 127
Query: 501 INNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRL 560
IN++HIHGE+KEFVC W CSRE +PFKAQYMLVVHMRRHTGEKPHKCTFEGC K+YSRL
Sbjct: 128 INSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRL 187
Query: 561 ENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTD 620
ENLKTHLRSHTGEKPY+CEHEGC+KAFSNASDRAKHQNRTHSNEKPYVCK+PGCTKRYTD
Sbjct: 188 ENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTD 247
Query: 621 PSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGSHSQSRSPGRPTQGALGEQQDLS 680
PSSLRKHVKTVHGP+AHVTK+ RGD P P P S + G P
Sbjct: 248 PSSLRKHVKTVHGPDAHVTKRHRGD-GPLPRAPSISTVEPKREREGGPI----------- 295
Query: 681 NTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPISNYSN--SGLELPLTDGGSI 738
REE + E M QPSPG QSSCSS SP + +N SG+E+ GGS
Sbjct: 296 -----REES---RLTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGST 347
Query: 739 GDLSAIDETPIMDSTISTATTALALQARRNPAGTKWMEHVKLERLKQVNGMFPRLNPILP 798
DLS++DE P + A T L+ R +E+++L++L Q L PI
Sbjct: 348 EDLSSLDEGPCI------AGTGLSTLRR--------LENLRLDQLHQ-------LRPI-- 384
Query: 799 PKAPAVSPLIGNGTQSNNTCSLGGPMTLLPGRSDLSGVDVTMLNMLNRRDSSASTISSAY 858
GT+ SL T + R G V+ L RR SS+S+ISSAY
Sbjct: 385 ------------GTRGLKLPSLSHTGTTVSRR---VGPPVS----LERRSSSSSSISSAY 425
Query: 859 LSSRRSSGISPCFSSRRSSEASQAEGRPQNVSVADSYDPISTDASRRSSEASQSDGLPSL 918
SRRSS SP + P S +G SL
Sbjct: 426 TVSRRSSLASP-------------------------FPPGS----------PPENGASSL 450
Query: 919 LSLTPAQQYRLKAKYAAAT-GGPPPTPLPNMERMSLKTRLALLGDALEPGVALPPVHAPR 977
L PAQ Y L+A+YA+A GG PT +++R+ G+ +PP
Sbjct: 451 PGLMPAQHYLLRARYASARGGGTSPTAASSLDRIG--------------GLPMPP----- 491
Query: 978 RCSDGGAHGYGRRHLQPHDAPGHGV-RRASDPVRTGSEGLALPRVPRFSSLSSCN-PPAM 1035
+ R P P GV RRASDP + ++ A RV RF SL + PP +
Sbjct: 492 ---------WRSRAEYPGYNPNAGVTRRASDPAQ-AADRPAPARVQRFKSLGCVHTPPTV 541
Query: 1036 ATSAEKRSLVLQNYTRPEGGQSRNFHSSPCPPSITENVTLESLTMDADANLNDE------ 1089
A + L SP PPSITEN +++ + + +
Sbjct: 542 AGGGQNFDPYLPTSV-----------YSPQPPSITENAAMDARGLQEEPEVGTSMVGSGL 590
Query: 1090 ----DFLPDDVVQYLNSQNQAGYEQHFPSALPDDSKVPHGPGDFDAPGLPDSHAGQQFHA 1145
DF P D + Y + A P +P GPG P ++ G
Sbjct: 591 NPYMDFPPTDTLGYGGPEGAAAE----PYGARGPGSLPLGPG-------PPTNYG----- 634
Query: 1146 LEQPCPEGSKTDLPIQ--WNEVSSGSADLSSSKLKCGPRPAVPQTRAFGFCNGMVVHPQN 1203
PCP+ + P Q W E S S K G P+ +G + V P+
Sbjct: 635 -PNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALGGTYSQCPRLEHYG---QVQVKPEQ 690
Query: 1204 --PLRSGPAGGYQTLGENSNPYGGPEH 1228
P+ S G L N++P GP H
Sbjct: 691 GCPVGSDSTGLAPCL--NAHPSEGPPH 715
Score = 42.4 bits (98), Expect = 0.004
Identities = 37/98 (37%), Positives = 48/98 (48%), Gaps = 20/98 (20%)
Query: 1479 LLSPGANQVTSTVDSLDSHDLEGVQIDFDAIIDDGDHSSLMSGALSPSIIQNLSHSSSRL 1538
L P QV + +DSLD L+ Q+DF AI+D+ LSP + SS
Sbjct: 897 LYPPPEGQVCNPLDSLD---LDNTQLDFVAILDEPQ-------GLSPPPSHDQRGSSGH- 945
Query: 1539 TTPRASLPFPALSMSTTNMAIGDMSSLLTSLAEESKFL 1576
TP S P NMA+G+MS LL SL E++FL
Sbjct: 946 -TPPPSGP--------PNMAVGNMSVLLRSLPGETEFL 974
>gi|109637784 GLIS family zinc finger 3 isoform a [Homo sapiens]
Length = 930
Score = 261 bits (667), Expect = 4e-69
Identities = 194/503 (38%), Positives = 243/503 (48%), Gaps = 47/503 (9%)
Query: 262 GTGAIHMEYLHAMDSTRFSSPRLSARPSRKRTLSISPLSDH-SFDLQTMIRTSPNSLVTI 320
GT + H Y S R SS R + S+KR LS+SPLSD D T+IRTSP SLV
Sbjct: 275 GTESSHSPY----PSPRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAY 330
Query: 321 LNNSRSSSSASGSYGHLSASAISPALSFTYSSAPVSLHMHQQILSRQQSLGSAFGHSPPL 380
+N SR+S + + + S PV +++ A+G L
Sbjct: 331 INGSRASPANLSPQPEVYGHFLGVRGSCIPQPRPVPGSQKGVLVAPGGLALPAYGEDGAL 390
Query: 381 IHPAPTFPTQRPIPGI-PTVLNPVQVSSG-PSESSQNK-----PTSESAVSSTGD-PMHN 432
H Q G+ P ++N + V G P SQ+ E ST D P
Sbjct: 391 EHERMQ---QLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPPAP 447
Query: 433 KRSKIKPDEDLPSP-GARGQQEQPE----GTTLVKEEGDKDESKQEPEVIYETNCHWEGC 487
+ P P P A PE L + D+ + + + C W C
Sbjct: 448 PLPPLPPPPGPPPPYHAHAHLHHPELGPHAQQLALPQATLDDDGEMDGIGGKHCCRWIDC 507
Query: 488 AREFDTQEQLVHHINNDHIHGEKKE-FVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
+ +D QE+LV HI HI K E F C W C R KPF A+Y L++HMR H+GEKP+
Sbjct: 508 SALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPN 567
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
KCTFEGC KA+SRLENLK HLRSHTGEKPY+C+H GC KAFSN+SDRAKHQ RTH + KP
Sbjct: 568 KCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQ-RTHLDTKP 626
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRG--DIHP-------------RPP 651
Y C+IPGCTKRYTDPSSLRKHVK E KK R ++HP
Sbjct: 627 YACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELHPDLLTDCLTVQSLQPAT 686
Query: 652 PPRDSGSH-SQSRSPGRPTQGALGEQQDLSNTTSKREECLQVKTVKAEKPMTSQPSPG-- 708
PRD+ + + RSPG P SN +S+ V P+ S PSPG
Sbjct: 687 SPRDAAAEGTVGRSPG-PGPDLYSAPIFSSNYSSRSGTA--AGAVPPPHPV-SHPSPGHN 742
Query: 709 --GQSSCSSQQSPISNYSNSGLE 729
G S Q P ++G E
Sbjct: 743 VQGSPHNPSSQLPPLTAVDAGAE 765
>gi|109637782 GLIS family zinc finger 3 isoform b [Homo sapiens]
Length = 775
Score = 261 bits (667), Expect = 4e-69
Identities = 194/503 (38%), Positives = 243/503 (48%), Gaps = 47/503 (9%)
Query: 262 GTGAIHMEYLHAMDSTRFSSPRLSARPSRKRTLSISPLSDH-SFDLQTMIRTSPNSLVTI 320
GT + H Y S R SS R + S+KR LS+SPLSD D T+IRTSP SLV
Sbjct: 120 GTESSHSPY----PSPRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAY 175
Query: 321 LNNSRSSSSASGSYGHLSASAISPALSFTYSSAPVSLHMHQQILSRQQSLGSAFGHSPPL 380
+N SR+S + + + S PV +++ A+G L
Sbjct: 176 INGSRASPANLSPQPEVYGHFLGVRGSCIPQPRPVPGSQKGVLVAPGGLALPAYGEDGAL 235
Query: 381 IHPAPTFPTQRPIPGI-PTVLNPVQVSSG-PSESSQNK-----PTSESAVSSTGD-PMHN 432
H Q G+ P ++N + V G P SQ+ E ST D P
Sbjct: 236 EHERMQ---QLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPPAP 292
Query: 433 KRSKIKPDEDLPSP-GARGQQEQPE----GTTLVKEEGDKDESKQEPEVIYETNCHWEGC 487
+ P P P A PE L + D+ + + + C W C
Sbjct: 293 PLPPLPPPPGPPPPYHAHAHLHHPELGPHAQQLALPQATLDDDGEMDGIGGKHCCRWIDC 352
Query: 488 AREFDTQEQLVHHINNDHIHGEKKE-FVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
+ +D QE+LV HI HI K E F C W C R KPF A+Y L++HMR H+GEKP+
Sbjct: 353 SALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPN 412
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
KCTFEGC KA+SRLENLK HLRSHTGEKPY+C+H GC KAFSN+SDRAKHQ RTH + KP
Sbjct: 413 KCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQ-RTHLDTKP 471
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRG--DIHP-------------RPP 651
Y C+IPGCTKRYTDPSSLRKHVK E KK R ++HP
Sbjct: 472 YACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELHPDLLTDCLTVQSLQPAT 531
Query: 652 PPRDSGSH-SQSRSPGRPTQGALGEQQDLSNTTSKREECLQVKTVKAEKPMTSQPSPG-- 708
PRD+ + + RSPG P SN +S+ V P+ S PSPG
Sbjct: 532 SPRDAAAEGTVGRSPG-PGPDLYSAPIFSSNYSSRSGTA--AGAVPPPHPV-SHPSPGHN 587
Query: 709 --GQSSCSSQQSPISNYSNSGLE 729
G S Q P ++G E
Sbjct: 588 VQGSPHNPSSQLPPLTAVDAGAE 610
>gi|166706915 GLIS family zinc finger 1 [Homo sapiens]
Length = 620
Score = 225 bits (574), Expect = 2e-58
Identities = 106/175 (60%), Positives = 123/175 (70%), Gaps = 6/175 (3%)
Query: 482 CHWEGCAREFDTQEQLVHHINNDHIHGEKKE-FVCRWLDCSREQKPFKAQYMLVVHMRRH 540
C W C ++ QE+LV HI HI K E F C W C R KPF A+Y L++HMR H
Sbjct: 197 CRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVH 256
Query: 541 TGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRT 600
+GEKP+KC FEGC+KA+SRLENLK HLRSHTGEKPY+C+H GC KAFSN+SDRAKHQ RT
Sbjct: 257 SGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQ-RT 315
Query: 601 HSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRD 655
H + KPY C+IPGC+KRYTDPSSLRKHVK E V KK +H P D
Sbjct: 316 HLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKK----LHAGPDTEAD 366
>gi|110431364 GLIS family zinc finger 2 [Homo sapiens]
Length = 524
Score = 194 bits (493), Expect = 6e-49
Identities = 90/173 (52%), Positives = 118/173 (68%), Gaps = 5/173 (2%)
Query: 482 CHWEGCAREFDTQEQLVHHINNDHIHGEKKE-FVCRWLDCSREQKPFKAQYMLVVHMRRH 540
C W C + F+ + LV H+N+ H+ EK + C W C+R + F A+Y +++H+R H
Sbjct: 170 CRWAKCNQLFELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTH 229
Query: 541 TGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRT 600
T EKPH+C C+K++SRLENLK H RSHTGEKPYVC +EGCNK +SN+SDR KH RT
Sbjct: 230 TNEKPHRCPT--CSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKH-TRT 286
Query: 601 HSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPP 653
H +KPY CK+PGC KRYTDPSSLRKH+K HG +++ + P P PP
Sbjct: 287 HYVDKPYYCKMPGCHKRYTDPSSLRKHIK-AHGHFVSHEQQELLQLRPPPKPP 338
>gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]
Length = 663
Score = 185 bits (470), Expect = 3e-46
Identities = 93/201 (46%), Positives = 121/201 (60%), Gaps = 20/201 (9%)
Query: 487 CAREFDTQEQLVHHINNDHIHG-EKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKP 545
C++ F T +LV+H+ +H+ G E+ VC W DC RE KPFKA+Y L+ H+R HTGEKP
Sbjct: 431 CSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKP 490
Query: 546 HKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 605
C F GC K ++R ENLK H R+HTGEKP+ CE +GC++ F+N+SDR KH + H+++K
Sbjct: 491 FPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKH-SHVHTSDK 549
Query: 606 PYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDS--GSHSQSR 663
PY CKI GC K YT PSSLRKH+K IH + PPP G S
Sbjct: 550 PYYCKIRGCDKSYTHPSSLRKHMK----------------IHCKSPPPSPGPLGYSSVGT 593
Query: 664 SPGRPTQGALGEQQDLSNTTS 684
G P L + S+T S
Sbjct: 594 PVGAPLSPVLDPARSHSSTLS 614
>gi|22547201 zinc finger protein of the cerebellum 4 [Homo sapiens]
Length = 334
Score = 181 bits (458), Expect = 6e-45
Identities = 88/183 (48%), Positives = 115/183 (62%), Gaps = 21/183 (11%)
Query: 487 CAREFDTQEQLVHHINNDHIHG-EKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKP 545
C++ F T +LV H+ +H+ G E+ +C W +C R+ KPFKA+Y LV H+R HTGEKP
Sbjct: 144 CSKTFSTMHELVTHVTVEHVGGPEQANHICFWEECPRQGKPFKAKYKLVNHIRVHTGEKP 203
Query: 546 HKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 605
C F GC K ++R ENLK H R+HTGEKP+ CE EGC + F+N+SDR KH + H+++K
Sbjct: 204 FPCPFPGCGKVFARSENLKIHKRTHTGEKPFRCEFEGCERRFANSSDRKKH-SHVHTSDK 262
Query: 606 PYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPR---DSGSHSQS 662
PY CK+ GC K YT PSSLRKH+K +H R PPP DS + S
Sbjct: 263 PYTCKVRGCDKCYTHPSSLRKHMK----------------VHGRSPPPSSGYDSATPSAL 306
Query: 663 RSP 665
SP
Sbjct: 307 VSP 309
Score = 94.4 bits (233), Expect = 8e-19
Identities = 47/128 (36%), Positives = 67/128 (52%), Gaps = 10/128 (7%)
Query: 482 CHWEGCARE---FDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMR 538
C WE C R+ F + +LV+HI +H +K F C + C K F L +H R
Sbjct: 173 CFWEECPRQGKPFKAKYKLVNHI---RVHTGEKPFPCPFPGCG---KVFARSENLKIHKR 226
Query: 539 RHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQN 598
HTGEKP +C FEGC + ++ + K H HT +KPY C+ GC+K +++ S KH
Sbjct: 227 THTGEKPFRCEFEGCERRFANSSDRKKHSHVHTSDKPYTCKVRGCDKCYTHPSSLRKHM- 285
Query: 599 RTHSNEKP 606
+ H P
Sbjct: 286 KVHGRSPP 293
>gi|4507973 zinc finger protein of the cerebellum 3 [Homo sapiens]
Length = 467
Score = 176 bits (445), Expect = 2e-43
Identities = 87/194 (44%), Positives = 119/194 (61%), Gaps = 15/194 (7%)
Query: 479 ETNCHW----------EGCAREFDTQEQLVHHINNDHIHG-EKKEFVCRWLDCSREQKPF 527
E +C W + C R F T +LV H+ +H+ G E+ VC W +C RE K F
Sbjct: 250 ELSCKWIDEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSF 309
Query: 528 KAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAF 587
KA+Y LV H+R HTGEKP C F GC K ++R ENLK H R+HTGEKP+ CE EGC++ F
Sbjct: 310 KAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRF 369
Query: 588 SNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIH 647
+N+SDR KH + H+++KPY+CK+ C K YT PSSLRKH+K VH + + +
Sbjct: 370 ANSSDRKKHMH-VHTSDKPYICKV--CDKSYTHPSSLRKHMK-VHESQGSDSSPAASSGY 425
Query: 648 PRPPPPRDSGSHSQ 661
PP + ++S+
Sbjct: 426 ESSTPPAIASANSK 439
>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
Length = 532
Score = 175 bits (443), Expect = 4e-43
Identities = 91/198 (45%), Positives = 121/198 (61%), Gaps = 17/198 (8%)
Query: 485 EGCAREFDTQEQLVHHINNDHIHG-EKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGE 543
+ C + F T +LV H++ +H+ G E+ VC W +C RE KPFKA+Y LV H+R HTGE
Sbjct: 271 KSCNKTFSTMHELVTHVSVEHVGGPEQSNHVCFWEECPREGKPFKAKYKLVNHIRVHTGE 330
Query: 544 KPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSN 603
KP C F GC K ++R ENLK H R+HTGEKP+ CE EGC++ F+N+SDR KH + H++
Sbjct: 331 KPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMH-VHTS 389
Query: 604 EKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGSHSQSR 663
+KPY+CK+ C K YT PSSLRKH+K H + Q + P S + S
Sbjct: 390 DKPYLCKM--CDKSYTHPSSLRKHMK------VHESSPQGSE-----SSPAASSGYESST 436
Query: 664 SPGRPTQGALGEQQDLSN 681
PG + A E Q SN
Sbjct: 437 PPGLVSPSA--EPQSSSN 452
Score = 89.0 bits (219), Expect = 3e-17
Identities = 45/118 (38%), Positives = 66/118 (55%), Gaps = 11/118 (9%)
Query: 482 CHWEGCARE---FDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMR 538
C WE C RE F + +LV+HI +H +K F C + C K F L +H R
Sbjct: 302 CFWEECPREGKPFKAKYKLVNHI---RVHTGEKPFPCPFPGCG---KVFARSENLKIHKR 355
Query: 539 RHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKH 596
HTGEKP +C FEGC + ++ + K H+ HT +KPY+C+ C+K++++ S KH
Sbjct: 356 THTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKM--CDKSYTHPSSLRKH 411
>gi|22547182 zinc finger protein of the cerebellum 1 [Homo sapiens]
Length = 447
Score = 174 bits (442), Expect = 5e-43
Identities = 91/207 (43%), Positives = 122/207 (58%), Gaps = 20/207 (9%)
Query: 485 EGCAREFDTQEQLVHHINNDHIHG-EKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGE 543
+ C + F T +LV H+ +H+ G E+ +C W +C RE KPFKA+Y LV H+R HTGE
Sbjct: 240 KSCNKTFSTMHELVTHVTVEHVGGPEQSNHICFWEECPREGKPFKAKYKLVNHIRVHTGE 299
Query: 544 KPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSN 603
KP C F GC K ++R ENLK H R+HTGEKP+ CE EGC++ F+N+SDR KH + H++
Sbjct: 300 KPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMH-VHTS 358
Query: 604 EKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGSHSQ-- 661
+KPY+CK+ C K YT PSSLRKH+K H + Q +P P SG S
Sbjct: 359 DKPYLCKM--CDKSYTHPSSLRKHMK------VHESSSQGS----QPSPAASSGYESSTP 406
Query: 662 ----SRSPGRPTQGALGEQQDLSNTTS 684
S S PT +L + T+
Sbjct: 407 PTIVSPSTDNPTTSSLSPSSSAVHHTA 433
Score = 90.9 bits (224), Expect = 9e-18
Identities = 47/127 (37%), Positives = 69/127 (54%), Gaps = 11/127 (8%)
Query: 482 CHWEGCARE---FDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMR 538
C WE C RE F + +LV+HI +H +K F C + C K F L +H R
Sbjct: 271 CFWEECPREGKPFKAKYKLVNHI---RVHTGEKPFPCPFPGCG---KVFARSENLKIHKR 324
Query: 539 RHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQN 598
HTGEKP KC FEGC + ++ + K H+ HT +KPY+C+ C+K++++ S KH
Sbjct: 325 THTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKM--CDKSYTHPSSLRKHMK 382
Query: 599 RTHSNEK 605
S+ +
Sbjct: 383 VHESSSQ 389
>gi|116014328 zinc finger protein 143 [Homo sapiens]
Length = 638
Score = 134 bits (336), Expect = 9e-31
Identities = 93/292 (31%), Positives = 136/292 (46%), Gaps = 27/292 (9%)
Query: 482 CHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHT 541
C GC + F T L H+ H +K + C +C+ K FK L H+R HT
Sbjct: 269 CEHAGCGKAFATGYGLKSHVRT---HTGEKPYRCSEDNCT---KSFKTSGDLQKHIRTHT 322
Query: 542 GEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTH 601
GE+P KC FEGC ++++ K H+R+HTGE+PY C GC +AF++A++ H R H
Sbjct: 323 GERPFKCPFEGCGRSFTTSNIRKVHVRTHTGERPYYCTEPGCGRAFASATNYKNHV-RIH 381
Query: 602 SNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGSHSQ 661
+ EKPYVC +PGC KR+T+ SSL KH H K H + S
Sbjct: 382 TGEKPYVCTVPGCDKRFTEYSSLYKH------HVVHTHSKPYNCNHCGKTYKQISTLAMH 435
Query: 662 SRSPGRPTQGALGEQQDL-------SNTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCS 714
R+ T+ EQ+ K + V V+ + +++Q + QS S
Sbjct: 436 KRTAHNDTEPIEEEQEAFFEPPPGQGEDVLKGSQITYVTGVEGDDVVSTQVATVTQSGLS 495
Query: 715 SQQSPISNYSNSGLELPLTDGGSIGDLSAI---DETPIM----DSTISTATT 759
Q + IS + + D +IG+ + D TPI D+ IS+A T
Sbjct: 496 QQVTLISQDGTQHVNISQADMQAIGNTITMVTQDGTPITVPAHDAVISSAGT 547
Score = 105 bits (263), Expect = 3e-22
Identities = 49/124 (39%), Positives = 73/124 (58%), Gaps = 4/124 (3%)
Query: 510 KKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRS 569
+K F C + C K + + L VH R HTG++P++C GC KA++ LK+H+R+
Sbjct: 234 EKAFRCEYDGCG---KLYTTAHHLKVHERSHTGDRPYQCEHAGCGKAFATGYGLKSHVRT 290
Query: 570 HTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVK 629
HTGEKPY C + C K+F + D KH RTH+ E+P+ C GC + +T + + HV+
Sbjct: 291 HTGEKPYRCSEDNCTKSFKTSGDLQKH-IRTHTGERPFKCPFEGCGRSFTTSNIRKVHVR 349
Query: 630 TVHG 633
T G
Sbjct: 350 THTG 353
Score = 99.8 bits (247), Expect = 2e-20
Identities = 49/112 (43%), Positives = 63/112 (56%), Gaps = 7/112 (6%)
Query: 528 KAQYMLVVHMRRHT------GEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHE 581
K Q +L H R T GEK +C ++GC K Y+ +LK H RSHTG++PY CEH
Sbjct: 213 KMQIVLQGHATRVTAKSQQSGEKAFRCEYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHA 272
Query: 582 GCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHG 633
GC KAF+ H RTH+ EKPY C CTK + L+KH++T G
Sbjct: 273 GCGKAFATGYGLKSHV-RTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTG 323
Score = 55.8 bits (133), Expect = 3e-07
Identities = 47/163 (28%), Positives = 74/163 (45%), Gaps = 26/163 (15%)
Query: 571 TGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKT 630
+GEK + CE++GC K ++ A H+ R+H+ ++PY C+ GC K + L+ HV+T
Sbjct: 232 SGEKAFRCEYDGCGKLYTTAHHLKVHE-RSHTGDRPYQCEHAGCGKAFATGYGLKSHVRT 290
Query: 631 VHG------PEAHVTK--KQRGDIHPRPPPPRDSGSHSQSRSPGRPTQGALGEQQDLSNT 682
G E + TK K GD+ + +H+ R P +G S T
Sbjct: 291 HTGEKPYRCSEDNCTKSFKTSGDLQ------KHIRTHTGERPFKCPFEGC-----GRSFT 339
Query: 683 TSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPISNYSN 725
TS + + V+T E+P PG C + +NY N
Sbjct: 340 TSNIRK-VHVRTHTGERPYYC-TEPG----CGRAFASATNYKN 376
>gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]
Length = 753
Score = 126 bits (317), Expect = 1e-28
Identities = 105/353 (29%), Positives = 154/353 (43%), Gaps = 58/353 (16%)
Query: 478 YETNCHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHM 537
Y C+ EGC + F T L H+ +H ++K F C C +K F Y L H
Sbjct: 168 YTFVCNQEGCGKAFLTSYSLRIHVR---VHTKEKPFECDVQGC---EKAFNTLYRLKAHQ 221
Query: 538 RRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQ 597
R HTG K C EGC+K ++ L +L+ H+R+HTGEKP+ C+H+GC KAF+ AS K
Sbjct: 222 RLHTG-KTFNCESEGCSKYFTTLSDLRKHIRTHTGEKPFRCDHDGCGKAFA-ASHHLKTH 279
Query: 598 NRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSG 657
RTH+ E+P+ C GC K ++ SL+ H+K H K H P+ +G
Sbjct: 280 VRTHTGERPFFCPSNGCEKTFSTQYSLKSHMK------GHDNKG-----HSYNALPQHNG 328
Query: 658 SHSQSRSPGRPTQGALGEQQDLSNTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQ 717
S + S L + LS + RE T + + T P+ +S
Sbjct: 329 SEDTNHSL------CLSDLSLLSTDSELRENS---STTQGQDLSTISPAIIFESM----- 374
Query: 718 SPISNYSNSGLELPLTDGGSIGDLSAIDETPIMDSTISTATTALALQARRNPAGTKWMEH 777
+ NS D +AI E P ++++ + A P T
Sbjct: 375 -----FQNS-------------DDTAIQEDPQQTASLTESFNGDAESVSDVPPSTGNSAS 416
Query: 778 VKLERLKQVNGMFPRLNPILP---PKAPAVSPLIGNGTQSNNTCSLGGPMTLL 827
+ L + Q G+ P+LP P AP +P +G G+Q + G P LL
Sbjct: 417 LSLPLVLQ-PGLSEPPQPLLPASAPSAPPPAPSLGPGSQQ---AAFGNPPALL 465
Score = 81.6 bits (200), Expect = 5e-15
Identities = 36/84 (42%), Positives = 49/84 (58%), Gaps = 1/84 (1%)
Query: 544 KPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSN 603
K ++CTFEGC + YS NL+TH ++H GE +VC EGC KAF + H R H+
Sbjct: 138 KRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHV-RVHTK 196
Query: 604 EKPYVCKIPGCTKRYTDPSSLRKH 627
EKP+ C + GC K + L+ H
Sbjct: 197 EKPFECDVQGCEKAFNTLYRLKAH 220
Score = 32.7 bits (73), Expect = 2.9
Identities = 20/77 (25%), Positives = 28/77 (36%), Gaps = 5/77 (6%)
Query: 566 HLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLR 625
HL + G P EG + K + K Y C GC + Y+ +LR
Sbjct: 104 HLTINPGSTPMPRNIEGATLTLQSECPETKRKE-----VKRYQCTFEGCPRTYSTAGNLR 158
Query: 626 KHVKTVHGPEAHVTKKQ 642
H KT G V ++
Sbjct: 159 THQKTHRGEYTFVCNQE 175
>gi|21361146 zinc finger protein 76 (expressed in testis) [Homo
sapiens]
Length = 570
Score = 121 bits (304), Expect = 5e-27
Identities = 60/146 (41%), Positives = 84/146 (57%), Gaps = 7/146 (4%)
Query: 482 CHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHT 541
C + C + F T L H+ H +K + C CS K FK L H+R HT
Sbjct: 197 CDFPSCGKAFATGYGLKSHVRT---HTGEKPYKCPEELCS---KAFKTSGDLQKHVRTHT 250
Query: 542 GEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTH 601
GE+P +C FEGC ++++ K H+R+HTGE+PY C C + F++A++ H R H
Sbjct: 251 GERPFQCPFEGCGRSFTTSNIRKVHVRTHTGERPYTCPEPHCGRGFTSATNYKNHV-RIH 309
Query: 602 SNEKPYVCKIPGCTKRYTDPSSLRKH 627
+ EKPYVC +PGC KR+T+ SSL KH
Sbjct: 310 TGEKPYVCTVPGCGKRFTEYSSLYKH 335
Score = 117 bits (293), Expect = 9e-26
Identities = 57/157 (36%), Positives = 89/157 (56%), Gaps = 7/157 (4%)
Query: 482 CHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHT 541
C ++GC R + T L H + H + + C + C K F Y L H+R HT
Sbjct: 167 CGYKGCGRLYTTAHHLKVH---ERAHTGDRPYRCDFPSCG---KAFATGYGLKSHVRTHT 220
Query: 542 GEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTH 601
GEKP+KC E C+KA+ +L+ H+R+HTGE+P+ C EGC ++F+ ++ R H RTH
Sbjct: 221 GEKPYKCPEELCSKAFKTSGDLQKHVRTHTGERPFQCPFEGCGRSFTTSNIRKVHV-RTH 279
Query: 602 SNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHV 638
+ E+PY C P C + +T ++ + HV+ G + +V
Sbjct: 280 TGERPYTCPEPHCGRGFTSATNYKNHVRIHTGEKPYV 316
Score = 107 bits (267), Expect = 9e-23
Identities = 53/133 (39%), Positives = 76/133 (57%), Gaps = 10/133 (7%)
Query: 511 KEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSH 570
+ F C + C R + + L VH R HTG++P++C F C KA++ LK+H+R+H
Sbjct: 163 RAFRCGYKGCGRL---YTTAHHLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHVRTH 219
Query: 571 TGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKT 630
TGEKPY C E C+KAF + D KH RTH+ E+P+ C GC + +T + + HV+T
Sbjct: 220 TGEKPYKCPEELCSKAFKTSGDLQKHV-RTHTGERPFQCPFEGCGRSFTTSNIRKVHVRT 278
Query: 631 VHG------PEAH 637
G PE H
Sbjct: 279 HTGERPYTCPEPH 291
Score = 83.2 bits (204), Expect = 2e-15
Identities = 36/95 (37%), Positives = 55/95 (57%), Gaps = 1/95 (1%)
Query: 539 RHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQN 598
+ G++ +C ++GC + Y+ +LK H R+HTG++PY C+ C KAF+ H
Sbjct: 158 QQVGDRAFRCGYKGCGRLYTTAHHLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHV- 216
Query: 599 RTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHG 633
RTH+ EKPY C C+K + L+KHV+T G
Sbjct: 217 RTHTGEKPYKCPEELCSKAFKTSGDLQKHVRTHTG 251
Score = 69.7 bits (169), Expect = 2e-11
Identities = 40/120 (33%), Positives = 53/120 (44%), Gaps = 8/120 (6%)
Query: 482 CHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHT 541
C +EGC R F T H+ H ++ + C C R F + H+R HT
Sbjct: 257 CPFEGCGRSFTTSNIRKVHVRT---HTGERPYTCPEPHCGRG---FTSATNYKNHVRIHT 310
Query: 542 GEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTH 601
GEKP+ CT GC K ++ +L H HT KPY C C K + S A H+ H
Sbjct: 311 GEKPYVCTVPGCGKRFTEYSSLYKHHVVHTHCKPYTC--STCGKTYRQTSTLAMHKRSAH 368
>gi|10863995 zinc finger protein 410 [Homo sapiens]
Length = 478
Score = 113 bits (282), Expect = 2e-24
Identities = 63/177 (35%), Positives = 86/177 (48%), Gaps = 9/177 (5%)
Query: 456 EGTTLVKEEGDKDESKQEPEVIYETNCHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVC 515
E L +G +S P+V + C EGC R F +H+ H + F+C
Sbjct: 195 ENVHLGSGDGQSKDSGPLPQVEKKLKCTVEGCDRTFVWPAHFKYHLKT---HRNDRSFIC 251
Query: 516 RWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKP 575
C K F L VHMR H GEKP C GC K ++ NLK H R HTGEKP
Sbjct: 252 PAEGCG---KSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKP 308
Query: 576 YVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVH 632
++CE +GC ++F+ S KH HS EKP+ C++ C K ++ S H++ H
Sbjct: 309 FLCEAQGCGRSFAEYSSLRKHL-VVHSGEKPHQCQV--CGKTFSQSGSRNVHMRKHH 362
Score = 101 bits (251), Expect = 7e-21
Identities = 61/184 (33%), Positives = 93/184 (50%), Gaps = 21/184 (11%)
Query: 536 HMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAK 595
H++ H ++ C EGC K++ L+ LK H+R+H GEKP++C GC K F+ A +
Sbjct: 239 HLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKN 298
Query: 596 HQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAH------VTKKQRG--DIH 647
H+ R H+ EKP++C+ GC + + + SSLRKH+ G + H T Q G ++H
Sbjct: 299 HR-RIHTGEKPFLCEAQGCGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVH 357
Query: 648 PRPPPPRDSGSHSQSRSPGRPTQGALGEQQDLSNTTSKREECLQVKTVKAEKPMTSQPSP 707
R H Q + G Q E L ++ E + K + + M SQPS
Sbjct: 358 MRK-------HHLQLGAAGSQEQEQTAE--PLMGSSLLEEASVPSKNLVS---MNSQPSL 405
Query: 708 GGQS 711
GG+S
Sbjct: 406 GGES 409
Score = 40.8 bits (94), Expect = 0.010
Identities = 19/61 (31%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Query: 573 EKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVH 632
EK C EGC++ F + K+ +TH N++ ++C GC K + L+ H++T +
Sbjct: 216 EKKLKCTVEGCDRTFVWPA-HFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHN 274
Query: 633 G 633
G
Sbjct: 275 G 275
>gi|115583660 zinc finger protein 391 [Homo sapiens]
Length = 358
Score = 110 bits (276), Expect = 8e-24
Identities = 71/201 (35%), Positives = 101/201 (50%), Gaps = 19/201 (9%)
Query: 445 SPGARGQQEQPEGT-TLVKEEGDKDES---KQEPEVIYETNCHWEGCAREFDTQEQLVHH 500
SP QQ+ P+G + + + KD S K + C C + F Q L+ H
Sbjct: 68 SPNLDAQQKIPKGHGSPISRKNSKDNSDLIKHQRLFSQRKPCKCNECEKAFSYQSDLLVH 127
Query: 501 INNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRL 560
IHG +K F +C++ K F L+ H R HTGEKP++C C KA+SR
Sbjct: 128 ---SRIHGGEKPF-----ECNKCGKSFSRSTHLIEHQRTHTGEKPYECN--ECGKAFSRS 177
Query: 561 ENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTD 620
+L H R HTGEKPY C C KAFS +++ ++HQ RTH+ E+PY C C K + D
Sbjct: 178 THLSLHQRIHTGEKPYECSE--CGKAFSRSTNLSQHQ-RTHTQERPYKCN--ECGKAFGD 232
Query: 621 PSSLRKHVKTVHGPEAHVTKK 641
S++ +H + G + K
Sbjct: 233 RSTIIQHQRIHTGENPYECSK 253
Score = 90.5 bits (223), Expect = 1e-17
Identities = 53/151 (35%), Positives = 79/151 (52%), Gaps = 15/151 (9%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C + F L H H +++ + C +C K F + ++ H R HTGE P+
Sbjct: 198 CGKAFSRSTNLSQH---QRTHTQERPYKCN--ECG---KAFGDRSTIIQHQRIHTGENPY 249
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
+C+ C KA+S + +L H R+HTGE PY C C K FS +S +HQ R HS EKP
Sbjct: 250 ECS--KCGKAFSWISSLTEHQRTHTGENPYECSE--CGKVFSRSSSLTEHQ-RIHSGEKP 304
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAH 637
+ C++ C K ++ SSL H +T G + +
Sbjct: 305 HECRV--CGKGFSRSSSLIIHQRTHTGEKPY 333
Score = 85.5 bits (210), Expect = 4e-16
Identities = 51/141 (36%), Positives = 71/141 (50%), Gaps = 15/141 (10%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C + F + ++ H IH + + +CS+ K F L H R HTGE P+
Sbjct: 226 CGKAFGDRSTIIQH---QRIHTGENPY-----ECSKCGKAFSWISSLTEHQRTHTGENPY 277
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
+C+ C K +SR +L H R H+GEKP+ C C K FS +S HQ RTH+ EKP
Sbjct: 278 ECS--ECGKVFSRSSSLTEHQRIHSGEKPHECRV--CGKGFSRSSSLIIHQ-RTHTGEKP 332
Query: 607 YVCKIPGCTKRYTDPSSLRKH 627
Y C C K + S+L +H
Sbjct: 333 YKCN--DCGKAFCQSSTLIRH 351
Score = 71.2 bits (173), Expect = 7e-12
Identities = 38/86 (44%), Positives = 48/86 (55%), Gaps = 5/86 (5%)
Query: 519 DCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVC 578
+CS K F L H R H+GEKPH+C C K +SR +L H R+HTGEKPY C
Sbjct: 278 ECSECGKVFSRSSSLTEHQRIHSGEKPHECRV--CGKGFSRSSSLIIHQRTHTGEKPYKC 335
Query: 579 EHEGCNKAFSNASDRAKHQNRTHSNE 604
C KAF +S +HQ+ H+ E
Sbjct: 336 --NDCGKAFCQSSTLIRHQH-LHTKE 358
>gi|156415988 zinc finger and BTB domain containing 7B [Homo
sapiens]
Length = 539
Score = 105 bits (262), Expect = 3e-22
Identities = 81/287 (28%), Positives = 123/287 (42%), Gaps = 23/287 (8%)
Query: 368 QSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLNPVQVSSGPSESSQNKPTSESAVSSTG 427
Q+ G+ H L+ PT P V V S G P + +A G
Sbjct: 210 QTKGARANH---LVPEVPTVPAHPLTYEEEEVAGRVGSSGGSGPGDSYSPPTGTASPPEG 266
Query: 428 DPMHNKRSKIKPDEDLPSPGARGQQEQPEGTTLVKEEGDKDESKQEPEVI-YETNCHWEG 486
+ + +E+L P A G Q G L EE DE +P+++ Y ++ H +
Sbjct: 267 PQSYEPYEGEEEEEELVYPPAYGLA-QGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDN 325
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
A D+Q++LV + +C K L HMR HTGEKP
Sbjct: 326 LAPGLDSQDKLVRKRRSQMPQ-----------ECPVCHKIIHGAGKLPRHMRTHTGEKPF 374
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
C E C ++R + LK H+R HTGE+PY C H C F ++ D H + H+ ++P
Sbjct: 375 AC--EVCGVRFTRNDKLKIHMRKHTGERPYSCPH--CPARFLHSYDLKNHMH-LHTGDRP 429
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPP 653
Y C + C K + L++H+K + E ++++ D P PPP
Sbjct: 430 YECHL--CHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDAPPHYPPP 474
>gi|239752951 PREDICTED: similar to kruppel-related zinc finger
protein hcKrox isoform 3 [Homo sapiens]
Length = 573
Score = 105 bits (262), Expect = 3e-22
Identities = 81/287 (28%), Positives = 123/287 (42%), Gaps = 23/287 (8%)
Query: 368 QSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLNPVQVSSGPSESSQNKPTSESAVSSTG 427
Q+ G+ H L+ PT P V V S G P + +A G
Sbjct: 244 QTKGARANH---LVPEVPTVPAHPLTYEEEEVAGRVGSSGGSGPGDSYSPPTGTASPPEG 300
Query: 428 DPMHNKRSKIKPDEDLPSPGARGQQEQPEGTTLVKEEGDKDESKQEPEVI-YETNCHWEG 486
+ + +E+L P A G Q G L EE DE +P+++ Y ++ H +
Sbjct: 301 PQSYEPYEGEEEEEELVYPPAYGLA-QGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDN 359
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
A D+Q++LV + +C K L HMR HTGEKP
Sbjct: 360 LAPGLDSQDKLVRKRRSQMPQ-----------ECPVCHKIIHGAGKLPRHMRTHTGEKPF 408
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
C E C ++R + LK H+R HTGE+PY C H C F ++ D H + H+ ++P
Sbjct: 409 AC--EVCGVRFTRNDKLKIHMRKHTGERPYSCPH--CPARFLHSYDLKNHMH-LHTGDRP 463
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPP 653
Y C + C K + L++H+K + E ++++ D P PPP
Sbjct: 464 YECHL--CHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDAPPHYPPP 508
>gi|239752949 PREDICTED: similar to kruppel-related zinc finger
protein hcKrox isoform 1 [Homo sapiens]
Length = 539
Score = 105 bits (262), Expect = 3e-22
Identities = 81/287 (28%), Positives = 123/287 (42%), Gaps = 23/287 (8%)
Query: 368 QSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLNPVQVSSGPSESSQNKPTSESAVSSTG 427
Q+ G+ H L+ PT P V V S G P + +A G
Sbjct: 210 QTKGARANH---LVPEVPTVPAHPLTYEEEEVAGRVGSSGGSGPGDSYSPPTGTASPPEG 266
Query: 428 DPMHNKRSKIKPDEDLPSPGARGQQEQPEGTTLVKEEGDKDESKQEPEVI-YETNCHWEG 486
+ + +E+L P A G Q G L EE DE +P+++ Y ++ H +
Sbjct: 267 PQSYEPYEGEEEEEELVYPPAYGLA-QGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDN 325
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
A D+Q++LV + +C K L HMR HTGEKP
Sbjct: 326 LAPGLDSQDKLVRKRRSQMPQ-----------ECPVCHKIIHGAGKLPRHMRTHTGEKPF 374
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
C E C ++R + LK H+R HTGE+PY C H C F ++ D H + H+ ++P
Sbjct: 375 AC--EVCGVRFTRNDKLKIHMRKHTGERPYSCPH--CPARFLHSYDLKNHMH-LHTGDRP 429
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPP 653
Y C + C K + L++H+K + E ++++ D P PPP
Sbjct: 430 YECHL--CHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDAPPHYPPP 474
>gi|239752947 PREDICTED: similar to kruppel-related zinc finger
protein hcKrox isoform 2 [Homo sapiens]
Length = 539
Score = 105 bits (262), Expect = 3e-22
Identities = 81/287 (28%), Positives = 123/287 (42%), Gaps = 23/287 (8%)
Query: 368 QSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLNPVQVSSGPSESSQNKPTSESAVSSTG 427
Q+ G+ H L+ PT P V V S G P + +A G
Sbjct: 210 QTKGARANH---LVPEVPTVPAHPLTYEEEEVAGRVGSSGGSGPGDSYSPPTGTASPPEG 266
Query: 428 DPMHNKRSKIKPDEDLPSPGARGQQEQPEGTTLVKEEGDKDESKQEPEVI-YETNCHWEG 486
+ + +E+L P A G Q G L EE DE +P+++ Y ++ H +
Sbjct: 267 PQSYEPYEGEEEEEELVYPPAYGLA-QGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDN 325
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
A D+Q++LV + +C K L HMR HTGEKP
Sbjct: 326 LAPGLDSQDKLVRKRRSQMPQ-----------ECPVCHKIIHGAGKLPRHMRTHTGEKPF 374
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
C E C ++R + LK H+R HTGE+PY C H C F ++ D H + H+ ++P
Sbjct: 375 AC--EVCGVRFTRNDKLKIHMRKHTGERPYSCPH--CPARFLHSYDLKNHMH-LHTGDRP 429
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPP 653
Y C + C K + L++H+K + E ++++ D P PPP
Sbjct: 430 YECHL--CHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDAPPHYPPP 474
>gi|147905620 PR domain containing 9 [Homo sapiens]
Length = 894
Score = 105 bits (261), Expect = 5e-22
Identities = 61/155 (39%), Positives = 85/155 (54%), Gaps = 15/155 (9%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C R F Q L+ H H +K +VCR +C R F Q +L+ H R HTGEKP+
Sbjct: 669 CGRGFSWQSVLLTH---QRTHTGEKPYVCR--ECGRG---FSWQSVLLTHQRTHTGEKPY 720
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
C C + +S +L H R+HTGEKPYVC C + F + S +HQ RTH+ EKP
Sbjct: 721 VC--RECGRGFSNKSHLLRHQRTHTGEKPYVCRE--CGRGFRDKSHLLRHQ-RTHTGEKP 775
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKK 641
YVC+ C + + D S+L H +T G + +V ++
Sbjct: 776 YVCR--ECGRGFRDKSNLLSHQRTHTGEKPYVCRE 808
Score = 105 bits (261), Expect = 5e-22
Identities = 60/155 (38%), Positives = 86/155 (55%), Gaps = 15/155 (9%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C R F + L+ H H +K +VCR +C R F+ + L+ H R HTGEKP+
Sbjct: 725 CGRGFSNKSHLLRH---QRTHTGEKPYVCR--ECGRG---FRDKSHLLRHQRTHTGEKPY 776
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
C C + + NL +H R+HTGEKPYVC C + FSN S +HQ RTH+ EKP
Sbjct: 777 VC--RECGRGFRDKSNLLSHQRTHTGEKPYVCRE--CGRGFSNKSHLLRHQ-RTHTGEKP 831
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKK 641
YVC+ C + + + S L +H +T G + +V ++
Sbjct: 832 YVCR--ECGRGFRNKSHLLRHQRTHTGEKPYVCRE 864
Score = 100 bits (250), Expect = 9e-21
Identities = 62/155 (40%), Positives = 83/155 (53%), Gaps = 15/155 (9%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C R F + L+ H IH +K +VCR +C R F Q +L+ H R HTGEKP+
Sbjct: 557 CGRGFSWKSHLLIH---QRIHTGEKPYVCR--ECGRG---FSWQSVLLTHQRTHTGEKPY 608
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
C C + +SR L TH R HTGEKPYVC C + FS S HQ R H+ EKP
Sbjct: 609 VC--RECGRGFSRQSVLLTHQRRHTGEKPYVCRE--CGRGFSRQSVLLTHQRR-HTGEKP 663
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKK 641
YVC+ C + ++ S L H +T G + +V ++
Sbjct: 664 YVCR--ECGRGFSWQSVLLTHQRTHTGEKPYVCRE 696
Score = 94.7 bits (234), Expect = 6e-19
Identities = 84/304 (27%), Positives = 121/304 (39%), Gaps = 52/304 (17%)
Query: 375 GHSP-PLIHPAPT----FPTQR---------------PIPGIPTVLNPVQVSSGPSESSQ 414
G P P IHP P+ F +Q+ P P +L P G Q
Sbjct: 380 GREPKPEIHPCPSCCLAFSSQKFLSQHVERNHSSQNFPGPSARKLLQPENPCPGDQNQEQ 439
Query: 415 NKPTSESAVSSTGDPMHNKRSKIKPDEDLPSPGARGQQEQPEGTT-------LVKEEGDK 467
P S T +RSK+ +R P+G + EE +
Sbjct: 440 QYPDPHSRNDKTKGQEIKERSKLLNKRTWQREISRAFSSPPKGQMGSCRVGKRIMEEESR 499
Query: 468 DESKQEPE----------VIYETNCHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVCRW 517
K P + + C + F + ++ H H +K +VCR
Sbjct: 500 TGQKVNPGNTGKLFVGVGISRIAKVKYGECGQGFSVKSDVITH---QRTHTGEKLYVCR- 555
Query: 518 LDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYV 577
+C R F + L++H R HTGEKP+ C C + +S L TH R+HTGEKPYV
Sbjct: 556 -ECGRG---FSWKSHLLIHQRIHTGEKPYVC--RECGRGFSWQSVLLTHQRTHTGEKPYV 609
Query: 578 CEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAH 637
C C + FS S HQ R H+ EKPYVC+ C + ++ S L H + G + +
Sbjct: 610 CRE--CGRGFSRQSVLLTHQRR-HTGEKPYVCR--ECGRGFSRQSVLLTHQRRHTGEKPY 664
Query: 638 VTKK 641
V ++
Sbjct: 665 VCRE 668
Score = 89.7 bits (221), Expect = 2e-17
Identities = 51/124 (41%), Positives = 67/124 (54%), Gaps = 13/124 (10%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C R F + L+ H H +K +VCR +C R F + L+ H R HTGEKP+
Sbjct: 781 CGRGFRDKSNLLSH---QRTHTGEKPYVCR--ECGRG---FSNKSHLLRHQRTHTGEKPY 832
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
C C + + +L H R+HTGEKPYVC C + FS+ S HQ RTH+ EKP
Sbjct: 833 VC--RECGRGFRNKSHLLRHQRTHTGEKPYVCRE--CGRGFSDRSSLCYHQ-RTHTGEKP 887
Query: 607 YVCK 610
YVC+
Sbjct: 888 YVCR 891
Score = 67.4 bits (163), Expect = 1e-10
Identities = 37/95 (38%), Positives = 51/95 (53%), Gaps = 10/95 (10%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C R F + L+ H H +K +VCR +C R F+ + L+ H R HTGEKP+
Sbjct: 809 CGRGFSNKSHLLRH---QRTHTGEKPYVCR--ECGRG---FRNKSHLLRHQRTHTGEKPY 860
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHE 581
C C + +S +L H R+HTGEKPYVC +
Sbjct: 861 VC--RECGRGFSDRSSLCYHQRTHTGEKPYVCRED 893
Score = 33.1 bits (74), Expect = 2.2
Identities = 27/124 (21%), Positives = 43/124 (34%), Gaps = 7/124 (5%)
Query: 605 KPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGSHSQSRS 664
KP + P C ++ L +HV+ H + R + P P P D Q
Sbjct: 384 KPEIHPCPSCCLAFSSQKFLSQHVERNHSSQNFPGPSARKLLQPENPCPGDQNQEQQYPD 443
Query: 665 PGRPTQGALGEQQDLSNTTSKREECLQVKTVKAE-KPMTSQPSPGGQSSCSSQQSPISNY 723
P G++ +R + L +T + E S P G SC + +
Sbjct: 444 PHSRNDKTKGQE------IKERSKLLNKRTWQREISRAFSSPPKGQMGSCRVGKRIMEEE 497
Query: 724 SNSG 727
S +G
Sbjct: 498 SRTG 501
>gi|4508035 zinc finger protein 7 [Homo sapiens]
Length = 686
Score = 104 bits (259), Expect = 8e-22
Identities = 65/169 (38%), Positives = 87/169 (51%), Gaps = 21/169 (12%)
Query: 478 YETNCHWEG------CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQY 531
+ NCH E C + F QL H IH +K F C +C K F+
Sbjct: 240 HTNNCHGEKPYECAECGKVFRLCSQLNQH---QRIHTGEKPFKCT--ECG---KAFRLSS 291
Query: 532 MLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNAS 591
L+ H R HTGEKP++C E C KA+ + +L H R HTGE+PY C C KAFS S
Sbjct: 292 KLIQHQRIHTGEKPYRC--EECGKAFGQSSSLIHHQRIHTGERPYGCRE--CGKAFSQQS 347
Query: 592 DRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTK 640
+HQ RTH+ E+PY CK C K ++ S+L +H + G +A + K
Sbjct: 348 QLVRHQ-RTHTGERPYPCK--ECGKAFSQSSTLAQHQRMHTGEKAQILK 393
Score = 85.5 bits (210), Expect = 4e-16
Identities = 53/137 (38%), Positives = 70/137 (51%), Gaps = 12/137 (8%)
Query: 501 INNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRL 560
+ + IH +K F C +C K F+ L H HTGEKP+KC CTKA+
Sbjct: 401 VAHQRIHAVEKPFKCD--ECG---KAFRWISRLSQHQLIHTGEKPYKCN--KCTKAFGCS 453
Query: 561 ENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTD 620
L H R+HTGEKP+ C+ C K F S +HQ R H+ EKPYVC C K ++
Sbjct: 454 SRLIRHQRTHTGEKPFKCDE--CGKGFVQGSHLIQHQ-RIHTGEKPYVCN--DCGKAFSQ 508
Query: 621 PSSLRKHVKTVHGPEAH 637
SSL H + G + +
Sbjct: 509 SSSLIYHQRIHKGEKPY 525
Score = 83.2 bits (204), Expect = 2e-15
Identities = 52/129 (40%), Positives = 65/129 (50%), Gaps = 12/129 (9%)
Query: 499 HHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYS 558
H I + IH +K +VC DC K F L+ H R H GEKP++C C KA+S
Sbjct: 483 HLIQHQRIHTGEKPYVCN--DCG---KAFSQSSSLIYHQRIHKGEKPYECL--QCGKAFS 535
Query: 559 RLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRY 618
L H R HTGE+PY C C KAFS S +HQ H+ KPY C C K +
Sbjct: 536 MSTQLTIHQRVHTGERPYKCNE--CGKAFSQNSTLFQHQ-IIHAGVKPYECS--ECGKAF 590
Query: 619 TDPSSLRKH 627
+ S L +H
Sbjct: 591 SRSSYLIEH 599
Score = 80.5 bits (197), Expect = 1e-14
Identities = 56/170 (32%), Positives = 75/170 (44%), Gaps = 28/170 (16%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYM-------------- 532
C + F Q QLV H H ++ + C+ + Q AQ+
Sbjct: 339 CGKAFSQQSQLVRH---QRTHTGERPYPCKECGKAFSQSSTLAQHQRMHTGEKAQILKAS 395
Query: 533 ----LVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFS 588
LV H R H EKP KC + C KA+ + L H HTGEKPY C C KAF
Sbjct: 396 DSPSLVAHQRIHAVEKPFKC--DECGKAFRWISRLSQHQLIHTGEKPYKCNK--CTKAFG 451
Query: 589 NASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHV 638
+S +HQ RTH+ EKP+ C C K + S L +H + G + +V
Sbjct: 452 CSSRLIRHQ-RTHTGEKPFKC--DECGKGFVQGSHLIQHQRIHTGEKPYV 498
Score = 69.7 bits (169), Expect = 2e-11
Identities = 55/195 (28%), Positives = 70/195 (35%), Gaps = 66/195 (33%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C + F L++H IH +K + C L C K F L +H R HTGE+P+
Sbjct: 502 CGKAFSQSSSLIYH---QRIHKGEKPYEC--LQCG---KAFSMSTQLTIHQRVHTGERPY 553
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQN-------- 598
KC C KA+S+ L H H G KPY C C KAFS +S +HQ
Sbjct: 554 KCN--ECGKAFSQNSTLFQHQIIHAGVKPYECSE--CGKAFSRSSYLIEHQRIHTRAQWF 609
Query: 599 --------------------------------------------RTHSNEKPYVCKIPGC 614
R H+ EKPY C C
Sbjct: 610 YEYGNALEGSTFVSRKKVNTIKKLHQCEDCEKIFRWRSHLIIHQRIHTGEKPYKCN--DC 667
Query: 615 TKRYTDPSSLRKHVK 629
K + S L +H K
Sbjct: 668 GKAFNRSSRLTQHQK 682
Score = 47.4 bits (111), Expect = 1e-04
Identities = 22/53 (41%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 520 CSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTG 572
C +K F+ + L++H R HTGEKP+KC C KA++R L H + H G
Sbjct: 636 CEDCEKIFRWRSHLIIHQRIHTGEKPYKC--NDCGKAFNRSSRLTQHQKIHMG 686
>gi|55769561 zinc finger protein 21 isoform 2 [Homo sapiens]
Length = 620
Score = 103 bits (258), Expect = 1e-21
Identities = 61/151 (40%), Positives = 81/151 (53%), Gaps = 15/151 (9%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C + F + L+ H H E+K + C +C K F+ + L++H R HTGEKP+
Sbjct: 472 CEKAFSQKSYLIIH---QRTHTEEKPYKCN--ECG---KAFREKSKLIIHQRIHTGEKPY 523
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
+C C KA+S+ L H R+HTGEKPY C C KAF S HQ RTH+ EKP
Sbjct: 524 ECPV--CWKAFSQKSQLIIHQRTHTGEKPYACTE--CGKAFREKSTFTVHQ-RTHTGEKP 578
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAH 637
Y C C K +T S+L H +T G +AH
Sbjct: 579 YKC--TECGKAFTQKSNLIVHQRTHAGKKAH 607
Score = 94.0 bits (232), Expect = 1e-18
Identities = 55/141 (39%), Positives = 74/141 (52%), Gaps = 15/141 (10%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C F + L+ H + H KK +C+ +K F + L++H R HTGEKPH
Sbjct: 332 CGESFIQKLDLIIHHST---HTGKKPH-----ECNECKKTFSDKSTLIIHQRTHTGEKPH 383
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
KCT C K+++ L H R+HTGEKPY C + C K F+ S+ HQ RTHS EKP
Sbjct: 384 KCT--ECGKSFNEKSTLIVHQRTHTGEKPYEC--DVCGKTFTQKSNLGVHQ-RTHSGEKP 438
Query: 607 YVCKIPGCTKRYTDPSSLRKH 627
+ C C K ++ S L H
Sbjct: 439 FECN--ECEKAFSQKSYLMLH 457
Score = 92.0 bits (227), Expect = 4e-18
Identities = 53/123 (43%), Positives = 68/123 (55%), Gaps = 7/123 (5%)
Query: 519 DCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVC 578
+C+ +K F + L+VH R HTGEKP CT C KA+S+ L HLR+HTGE+P+ C
Sbjct: 216 ECTACRKTFSKKSHLIVHWRTHTGEKPFGCT--ECGKAFSQKSQLIIHLRTHTGERPFEC 273
Query: 579 EHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHV 638
C KAF S H RTH+ EKPY C C K +T S+L H KT G + +
Sbjct: 274 PE--CGKAFREKSTVIIHY-RTHTGEKPYECN--ECGKAFTQKSNLIVHQKTHTGEKTYE 328
Query: 639 TKK 641
K
Sbjct: 329 CTK 331
Score = 89.0 bits (219), Expect = 3e-17
Identities = 51/151 (33%), Positives = 81/151 (53%), Gaps = 15/151 (9%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C + F + QL+ H+ H ++ F C +C K F+ + +++H R HTGEKP+
Sbjct: 248 CGKAFSQKSQLIIHLRT---HTGERPFECP--ECG---KAFREKSTVIIHYRTHTGEKPY 299
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
+C C KA+++ NL H ++HTGEK Y C C ++F D H + TH+ +KP
Sbjct: 300 EC--NECGKAFTQKSNLIVHQKTHTGEKTYECTK--CGESFIQKLDLIIHHS-THTGKKP 354
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAH 637
+ C C K ++D S+L H +T G + H
Sbjct: 355 HECN--ECKKTFSDKSTLIIHQRTHTGEKPH 383
Score = 87.0 bits (214), Expect = 1e-16
Identities = 56/151 (37%), Positives = 74/151 (49%), Gaps = 15/151 (9%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C + F+ + L+ H H +K + +C K F + L VH R H+GEKP
Sbjct: 388 CGKSFNEKSTLIVH---QRTHTGEKPY-----ECDVCGKTFTQKSNLGVHQRTHSGEKPF 439
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
+C C KA+S+ L H R HTGEKPY C C KAFS S HQ RTH+ EKP
Sbjct: 440 ECN--ECEKAFSQKSYLMLHQRGHTGEKPYECNE--CEKAFSQKSYLIIHQ-RTHTEEKP 494
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAH 637
Y C C K + + S L H + G + +
Sbjct: 495 YKCN--ECGKAFREKSKLIIHQRIHTGEKPY 523
Score = 75.9 bits (185), Expect = 3e-13
Identities = 42/105 (40%), Positives = 59/105 (56%), Gaps = 7/105 (6%)
Query: 533 LVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASD 592
L +H R GEKP +CT C K +S+ +L H R+HTGEKP+ C C KAFS S
Sbjct: 202 LSLHQRIKNGEKPFECT--ACRKTFSKKSHLIVHWRTHTGEKPFGCTE--CGKAFSQKSQ 257
Query: 593 RAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAH 637
H RTH+ E+P+ C P C K + + S++ H +T G + +
Sbjct: 258 LIIHL-RTHTGERPFEC--PECGKAFREKSTVIIHYRTHTGEKPY 299
Score = 53.5 bits (127), Expect = 2e-06
Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 7/96 (7%)
Query: 538 RRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQ 597
+ + G KP+ ++ C K R + L H R GEKP+ C C K FS S H
Sbjct: 179 KTNPGMKPYG--YKECGKGLRRKKGLSLHQRIKNGEKPFEC--TACRKTFSKKSHLIVHW 234
Query: 598 NRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHG 633
RTH+ EKP+ C C K ++ S L H++T G
Sbjct: 235 -RTHTGEKPFGC--TECGKAFSQKSQLIIHLRTHTG 267
>gi|55769559 zinc finger protein 21 isoform 1 [Homo sapiens]
Length = 639
Score = 103 bits (258), Expect = 1e-21
Identities = 61/151 (40%), Positives = 81/151 (53%), Gaps = 15/151 (9%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C + F + L+ H H E+K + C +C K F+ + L++H R HTGEKP+
Sbjct: 491 CEKAFSQKSYLIIH---QRTHTEEKPYKCN--ECG---KAFREKSKLIIHQRIHTGEKPY 542
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
+C C KA+S+ L H R+HTGEKPY C C KAF S HQ RTH+ EKP
Sbjct: 543 ECPV--CWKAFSQKSQLIIHQRTHTGEKPYACTE--CGKAFREKSTFTVHQ-RTHTGEKP 597
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAH 637
Y C C K +T S+L H +T G +AH
Sbjct: 598 YKC--TECGKAFTQKSNLIVHQRTHAGKKAH 626
Score = 94.0 bits (232), Expect = 1e-18
Identities = 55/141 (39%), Positives = 74/141 (52%), Gaps = 15/141 (10%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C F + L+ H + H KK +C+ +K F + L++H R HTGEKPH
Sbjct: 351 CGESFIQKLDLIIHHST---HTGKKPH-----ECNECKKTFSDKSTLIIHQRTHTGEKPH 402
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
KCT C K+++ L H R+HTGEKPY C + C K F+ S+ HQ RTHS EKP
Sbjct: 403 KCT--ECGKSFNEKSTLIVHQRTHTGEKPYEC--DVCGKTFTQKSNLGVHQ-RTHSGEKP 457
Query: 607 YVCKIPGCTKRYTDPSSLRKH 627
+ C C K ++ S L H
Sbjct: 458 FECN--ECEKAFSQKSYLMLH 476
Score = 92.0 bits (227), Expect = 4e-18
Identities = 53/123 (43%), Positives = 68/123 (55%), Gaps = 7/123 (5%)
Query: 519 DCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVC 578
+C+ +K F + L+VH R HTGEKP CT C KA+S+ L HLR+HTGE+P+ C
Sbjct: 235 ECTACRKTFSKKSHLIVHWRTHTGEKPFGCT--ECGKAFSQKSQLIIHLRTHTGERPFEC 292
Query: 579 EHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHV 638
C KAF S H RTH+ EKPY C C K +T S+L H KT G + +
Sbjct: 293 PE--CGKAFREKSTVIIHY-RTHTGEKPYECN--ECGKAFTQKSNLIVHQKTHTGEKTYE 347
Query: 639 TKK 641
K
Sbjct: 348 CTK 350
Score = 89.0 bits (219), Expect = 3e-17
Identities = 51/151 (33%), Positives = 81/151 (53%), Gaps = 15/151 (9%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C + F + QL+ H+ H ++ F C +C K F+ + +++H R HTGEKP+
Sbjct: 267 CGKAFSQKSQLIIHLRT---HTGERPFECP--ECG---KAFREKSTVIIHYRTHTGEKPY 318
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
+C C KA+++ NL H ++HTGEK Y C C ++F D H + TH+ +KP
Sbjct: 319 EC--NECGKAFTQKSNLIVHQKTHTGEKTYECTK--CGESFIQKLDLIIHHS-THTGKKP 373
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAH 637
+ C C K ++D S+L H +T G + H
Sbjct: 374 HECN--ECKKTFSDKSTLIIHQRTHTGEKPH 402
Score = 87.0 bits (214), Expect = 1e-16
Identities = 56/151 (37%), Positives = 74/151 (49%), Gaps = 15/151 (9%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C + F+ + L+ H H +K + +C K F + L VH R H+GEKP
Sbjct: 407 CGKSFNEKSTLIVH---QRTHTGEKPY-----ECDVCGKTFTQKSNLGVHQRTHSGEKPF 458
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
+C C KA+S+ L H R HTGEKPY C C KAFS S HQ RTH+ EKP
Sbjct: 459 ECN--ECEKAFSQKSYLMLHQRGHTGEKPYECNE--CEKAFSQKSYLIIHQ-RTHTEEKP 513
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAH 637
Y C C K + + S L H + G + +
Sbjct: 514 YKCN--ECGKAFREKSKLIIHQRIHTGEKPY 542
Score = 75.9 bits (185), Expect = 3e-13
Identities = 42/105 (40%), Positives = 59/105 (56%), Gaps = 7/105 (6%)
Query: 533 LVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASD 592
L +H R GEKP +CT C K +S+ +L H R+HTGEKP+ C C KAFS S
Sbjct: 221 LSLHQRIKNGEKPFECT--ACRKTFSKKSHLIVHWRTHTGEKPFGCTE--CGKAFSQKSQ 276
Query: 593 RAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAH 637
H RTH+ E+P+ C P C K + + S++ H +T G + +
Sbjct: 277 LIIHL-RTHTGERPFEC--PECGKAFREKSTVIIHYRTHTGEKPY 318
Score = 53.5 bits (127), Expect = 2e-06
Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 7/96 (7%)
Query: 538 RRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQ 597
+ + G KP+ ++ C K R + L H R GEKP+ C C K FS S H
Sbjct: 198 KTNPGMKPYG--YKECGKGLRRKKGLSLHQRIKNGEKPFEC--TACRKTFSKKSHLIVHW 253
Query: 598 NRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHG 633
RTH+ EKP+ C C K ++ S L H++T G
Sbjct: 254 -RTHTGEKPFGC--TECGKAFSQKSQLIIHLRTHTG 286
>gi|122937229 zinc finger protein 629 [Homo sapiens]
Length = 869
Score = 103 bits (258), Expect = 1e-21
Identities = 65/149 (43%), Positives = 79/149 (53%), Gaps = 16/149 (10%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C + F LV H H +K + C DC K F LV H R HTGEKP+
Sbjct: 183 CGKSFTQSSHLVQH---QRTHTGEKPYKCP--DCG---KCFSWSSNLVQHQRTHTGEKPY 234
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
KCT C KA+++ NL H RSHTGEKPY C C +AF +SD +HQ TH+ EKP
Sbjct: 235 KCT--ECEKAFTQSTNLIKHQRSHTGEKPYKCGE--CRRAFYRSSDLIQHQ-ATHTGEKP 289
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPE 635
Y C P C KR+ +L KH K +H E
Sbjct: 290 YKC--PECGKRFGQNHNLLKHQK-IHAGE 315
Score = 92.4 bits (228), Expect = 3e-18
Identities = 55/159 (34%), Positives = 82/159 (51%), Gaps = 16/159 (10%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C + F L++H IH ++ ++C DC K F L+ H R HTGEKP+
Sbjct: 407 CGKSFSVSSNLINH---QRIHRGERPYICA--DCG---KSFIMSSTLIRHQRIHTGEKPY 458
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
KC+ C K++ R +L H R+HTGEKPY C C K+FS +S+ H RTH +E
Sbjct: 459 KCS--DCGKSFIRSSHLIQHRRTHTGEKPYKCPE--CGKSFSQSSNLITHV-RTHMDENL 513
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGD 645
+VC C K + + L +H + +H ++ +GD
Sbjct: 514 FVCS--DCGKAFLEAHELEQH-RVIHERGKTPARRAQGD 549
Score = 87.8 bits (216), Expect = 7e-17
Identities = 50/130 (38%), Positives = 75/130 (57%), Gaps = 12/130 (9%)
Query: 508 GEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHL 567
G +K ++C +C K F L+ H R HTGE+P+ C+ C K++++ +L H
Sbjct: 145 GAEKPYICN--ECG---KSFSQWSKLLRHQRIHTGERPNTCS--ECGKSFTQSSHLVQHQ 197
Query: 568 RSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKH 627
R+HTGEKPY C C K FS +S+ +HQ RTH+ EKPY C C K +T ++L KH
Sbjct: 198 RTHTGEKPYKC--PDCGKCFSWSSNLVQHQ-RTHTGEKPYKC--TECEKAFTQSTNLIKH 252
Query: 628 VKTVHGPEAH 637
++ G + +
Sbjct: 253 QRSHTGEKPY 262
Score = 87.4 bits (215), Expect = 1e-16
Identities = 54/147 (36%), Positives = 76/147 (51%), Gaps = 15/147 (10%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C R F L+ H H +K + C +C K F + L+ H + H GEKP+
Sbjct: 267 CRRAFYRSSDLIQH---QATHTGEKPYKCP--ECG---KRFGQNHNLLKHQKIHAGEKPY 318
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
+CT C K++ + L H R+HTGEKPY C C K+F ++S KHQ RTH E P
Sbjct: 319 RCT--ECGKSFIQSSELTQHQRTHTGEKPYECLE--CGKSFGHSSTLIKHQ-RTHLREDP 373
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHG 633
+ C P C K +T ++L +H +T G
Sbjct: 374 FKC--PVCGKTFTLSATLLRHQRTHTG 398
Score = 78.2 bits (191), Expect = 6e-14
Identities = 50/151 (33%), Positives = 71/151 (47%), Gaps = 15/151 (9%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C + F +L H H +K + C L+C K F L+ H R H E P
Sbjct: 323 CGKSFIQSSELTQH---QRTHTGEKPYEC--LECG---KSFGHSSTLIKHQRTHLREDPF 374
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
KC C K ++ L H R+HTGE+PY C C K+FS +S+ HQ R H E+P
Sbjct: 375 KCPV--CGKTFTLSATLLRHQRTHTGERPYKCPE--CGKSFSVSSNLINHQ-RIHRGERP 429
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAH 637
Y+C C K + S+L +H + G + +
Sbjct: 430 YIC--ADCGKSFIMSSTLIRHQRIHTGEKPY 458
Score = 42.0 bits (97), Expect = 0.005
Identities = 32/115 (27%), Positives = 52/115 (45%), Gaps = 19/115 (16%)
Query: 528 KAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKP------------ 575
K+ +L+ H+R G +P++C+ C ++ L H +HT EKP
Sbjct: 750 KSSSVLLEHLRSPLGARPYRCS--DCRASFLDRVALTRHQETHTQEKPPNPEDPPPEAVT 807
Query: 576 --YVCEHEGCNKAFSNASDRAKHQN-RTHSNEKPYVCKIPGCTKRYTDPSSLRKH 627
E EG + +S + QN +T EKPY+C P C +T+ ++L H
Sbjct: 808 LSTDQEGEGETPTPTESSSHGEGQNPKTLVEEKPYLC--PECGAGFTEVAALLLH 860
Score = 35.8 bits (81), Expect = 0.34
Identities = 29/114 (25%), Positives = 41/114 (35%), Gaps = 31/114 (27%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSRE-QKPFKAQYMLVVHMRRHT---- 541
C + F L+ H+ H ++ FVC DC + + + + V+H R T
Sbjct: 491 CGKSFSQSSNLITHVRT---HMDENLFVCS--DCGKAFLEAHELEQHRVIHERGKTPARR 545
Query: 542 -------------------GEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPY 576
G KPHKC C K ++ H R H GE PY
Sbjct: 546 AQGDSLLGLGDPSLLTPPPGAKPHKCLV--CGKGFNDEGIFMQHQRIHIGENPY 597
>gi|64368880 zinc finger and SCAN domain containing 25 [Homo
sapiens]
Length = 544
Score = 103 bits (257), Expect = 1e-21
Identities = 59/151 (39%), Positives = 86/151 (56%), Gaps = 16/151 (10%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C + F +E L+ H H K+ +VC S K F ++ L VH R HTGEKP+
Sbjct: 380 CGKGFTLREYLMKH---QRTHLGKRPYVC-----SECWKTFSQRHHLEVHQRSHTGEKPY 431
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
KC C K++SR ++L+ H R+HTGEKPY CE C K+FS ++ A H+ R H+ EKP
Sbjct: 432 KCG--DCWKSFSRRQHLQVHRRTHTGEKPYTCE---CGKSFSRNANLAVHR-RAHTGEKP 485
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAH 637
Y C++ C KR++ L +H + G + +
Sbjct: 486 YGCQV--CGKRFSKGERLVRHQRIHTGEKPY 514
Score = 70.5 bits (171), Expect = 1e-11
Identities = 43/118 (36%), Positives = 57/118 (48%), Gaps = 13/118 (11%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C + F ++ L H H +K + C +C K F L VH R HTGEKP+
Sbjct: 436 CWKSFSRRQHLQVHRRT---HTGEKPYTC---ECG---KSFSRNANLAVHRRAHTGEKPY 486
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNE 604
C + C K +S+ E L H R HTGEKPY C C ++F+ S +HQ H E
Sbjct: 487 GC--QVCGKRFSKGERLVRHQRIHTGEKPYHC--PACGRSFNQRSILNRHQKTQHRQE 540
>gi|117956407 zinc finger protein 568 [Homo sapiens]
Length = 644
Score = 103 bits (256), Expect = 2e-21
Identities = 60/151 (39%), Positives = 82/151 (54%), Gaps = 15/151 (9%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C + F + H+ + H +K +VC +C K F L VHMR HT EKP+
Sbjct: 395 CGKAFSQCSVFIIHMRS---HTGEKPYVCS--ECG---KAFSQSSSLTVHMRNHTAEKPY 446
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
+C + C KA+SR ENL TH + HTGEKPY C C KAF S+ +HQ R H+ EKP
Sbjct: 447 EC--KECGKAFSRKENLITHQKIHTGEKPYECSE--CGKAFIQMSNLIRHQ-RIHTGEKP 501
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAH 637
Y C + C K ++ S+L +H K G + +
Sbjct: 502 YACTV--CGKAFSQKSNLTEHEKIHTGEKPY 530
Score = 99.0 bits (245), Expect = 3e-20
Identities = 61/163 (37%), Positives = 86/163 (52%), Gaps = 16/163 (9%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C + F + L+ H + IH +K + C+ +C K F + L+ H + HTGEKP+
Sbjct: 311 CWKAFSQKSNLIEH---ERIHTGEKPYECK--ECG---KSFSQKQNLIEHEKIHTGEKPY 362
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
C C +A+SR+ ++ H+RSHTGEKPY C C KAFS S H R+H+ EKP
Sbjct: 363 ACN--ECGRAFSRMSSVTLHMRSHTGEKPYKCNK--CGKAFSQCSVFIIHM-RSHTGEKP 417
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPR 649
YVC C K ++ SSL H++ H E K+ G R
Sbjct: 418 YVCS--ECGKAFSQSSSLTVHMRN-HTAEKPYECKECGKAFSR 457
Score = 93.6 bits (231), Expect = 1e-18
Identities = 60/151 (39%), Positives = 78/151 (51%), Gaps = 16/151 (10%)
Query: 487 CAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546
C + F + L H + IH +K + C C K F + L+ H + HTGEKP
Sbjct: 507 CGKAFSQKSNLTEH---EKIHTGEKPYHCN--QCG---KAFSQRQNLLEHEKIHTGEKPF 558
Query: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606
KC C KA+SR+ +L H+RSHTGEKPY C C KAFS S H R+H+ EKP
Sbjct: 559 KCN--ECGKAFSRISSLTLHVRSHTGEKPYECNK--CGKAFSQCSLLIIHM-RSHTGEKP 613
Query: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAH 637
+ C C K ++ +SL H K H E H
Sbjct: 614 FECN--ECGKAFSQRASLSIH-KRGHTGERH 641
Score = 93.2 bits (230), Expect = 2e-18
Identities = 57/157 (36%), Positives = 83/157 (52%), Gaps = 14/157 (8%)
Query: 485 EGCAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEK 544
+GC RE + E H +V C++ + F ++ L+ H R H GEK
Sbjct: 196 KGCVREKQSNE-----FGKPFYHCAS--YVVTPFKCNQCGQDFSHKFDLIRHERIHAGEK 248
Query: 545 PHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNE 604
P++C + C KA+SR ENL TH + HTGEKPY C C KAF S+ +H +R H+ E
Sbjct: 249 PYEC--KECGKAFSRKENLITHQKIHTGEKPYKCNE--CGKAFIQMSNLIRH-HRIHTGE 303
Query: 605 KPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKK 641
KPY CK C K ++ S+L +H + G + + K+
Sbjct: 304 KPYACK--DCWKAFSQKSNLIEHERIHTGEKPYECKE 338
Score = 63.2 bits (152), Expect = 2e-09
Identities = 43/150 (28%), Positives = 67/150 (44%), Gaps = 30/150 (20%)
Query: 453 EQPEGTTLVKEEGDKDESKQEPEVIY--ETNCHWEGCAREFDTQEQLVHHINNDHIHGEK 510
E+P T+ + + + E E I+ E H C + F ++ L+ H + IH +
Sbjct: 499 EKPYACTVCGKAFSQKSNLTEHEKIHTGEKPYHCNQCGKAFSQRQNLLEH---EKIHTGE 555
Query: 511 KEFVC-----------------------RWLDCSREQKPFKAQYMLVVHMRRHTGEKPHK 547
K F C + +C++ K F +L++HMR HTGEKP +
Sbjct: 556 KPFKCNECGKAFSRISSLTLHVRSHTGEKPYECNKCGKAFSQCSLLIIHMRSHTGEKPFE 615
Query: 548 CTFEGCTKAYSRLENLKTHLRSHTGEKPYV 577
C C KA+S+ +L H R HTGE+ V
Sbjct: 616 CN--ECGKAFSQRASLSIHKRGHTGERHQV 643
>gi|65507817 Wilms tumor 1 isoform B [Homo sapiens]
Length = 514
Score = 102 bits (254), Expect = 3e-21
Identities = 49/119 (41%), Positives = 72/119 (60%), Gaps = 6/119 (5%)
Query: 509 EKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLR 568
EK+ F+C + C++ FK + L +H R+HTGEKP++C F+ C + +SR + LK H R
Sbjct: 387 EKRPFMCAYPGCNKRY--FKLSH-LQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQR 443
Query: 569 SHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKH 627
HTG KP+ C + C + FS SD K RTH+ EKP+ C+ P C K++ L +H
Sbjct: 444 RHTGVKPFQC--KTCQRKFSR-SDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRH 499
Score = 84.7 bits (208), Expect = 6e-16
Identities = 43/122 (35%), Positives = 61/122 (50%), Gaps = 8/122 (6%)
Query: 482 CHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHT 541
C + GC + + L H H +K + C + DC R F L H RRHT
Sbjct: 393 CAYPGCNKRYFKLSHLQMHSRK---HTGEKPYQCDFKDCERR---FSRSDQLKRHQRRHT 446
Query: 542 GEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTH 601
G KP +C + C + +SR ++LKTH R+HTGEKP+ C C K F+ + + +H N
Sbjct: 447 GVKPFQC--KTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ 504
Query: 602 SN 603
N
Sbjct: 505 RN 506
Score = 80.9 bits (198), Expect = 9e-15
Identities = 39/101 (38%), Positives = 56/101 (55%), Gaps = 4/101 (3%)
Query: 534 VVHMRRHTGEK-PHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASD 592
+V T EK P C + GC K Y +L +L+ H R HTGEKPY C+ + C + FS SD
Sbjct: 378 LVRSASETSEKRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSR-SD 436
Query: 593 RAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHG 633
+ K R H+ KP+ CK C ++++ L+ H +T G
Sbjct: 437 QLKRHQRRHTGVKPFQCKT--CQRKFSRSDHLKTHTRTHTG 475
Score = 33.1 bits (74), Expect = 2.2
Identities = 13/36 (36%), Positives = 21/36 (58%)
Query: 602 SNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAH 637
S ++P++C PGC KRY S L+ H + G + +
Sbjct: 386 SEKRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPY 421
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,622,424
Number of Sequences: 37866
Number of extensions: 4085793
Number of successful extensions: 39658
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 961
Number of HSP's successfully gapped in prelim test: 407
Number of HSP's that attempted gapping in prelim test: 13063
Number of HSP's gapped (non-prelim): 7733
length of query: 1580
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1464
effective length of database: 13,855,062
effective search space: 20283810768
effective search space used: 20283810768
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.