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Search of human proteins with 11863156
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11863156 RECK protein precursor [Homo sapiens]
(971 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11863156 RECK protein precursor [Homo sapiens] 2061 0.0
gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens] 74 5e-13
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 64 5e-10
gi|54873613 agrin [Homo sapiens] 64 9e-10
gi|148727298 keratin associated protein 10-6 [Homo sapiens] 55 2e-07
gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] 52 2e-06
gi|154759249 keratin associated protein 10-11 [Homo sapiens] 52 4e-06
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 50 1e-05
gi|38490568 keratin associated protein 10-4 [Homo sapiens] 49 2e-05
gi|32140182 keratin associated protein 10-10 [Homo sapiens] 49 2e-05
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 48 5e-05
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 48 5e-05
gi|4557679 jagged 1 precursor [Homo sapiens] 47 1e-04
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ... 46 2e-04
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ... 45 3e-04
gi|153946395 tenascin C precursor [Homo sapiens] 45 4e-04
gi|61743978 stabilin 1 precursor [Homo sapiens] 44 7e-04
gi|38490571 keratin associated protein 10-7 [Homo sapiens] 44 7e-04
gi|238859649 keratin associated protein 10-8 [Homo sapiens] 44 0.001
gi|108773804 Fraser syndrome 1 [Homo sapiens] 43 0.001
gi|148833508 notch1 preproprotein [Homo sapiens] 43 0.002
gi|161019170 mucin 5AC [Homo sapiens] 42 0.002
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens] 42 0.002
gi|63053517 keratin associated protein 10-5 [Homo sapiens] 42 0.002
gi|134031945 SCO-spondin [Homo sapiens] 41 0.005
gi|63053512 keratin associated protein 10-1 [Homo sapiens] 41 0.005
gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens] 41 0.005
gi|126012573 low density lipoprotein-related protein 2 [Homo sap... 41 0.006
gi|93102379 low density lipoprotein-related protein 1B precursor... 40 0.014
gi|29568105 transmembrane protein with EGF-like and two follista... 40 0.014
>gi|11863156 RECK protein precursor [Homo sapiens]
Length = 971
Score = 2061 bits (5339), Expect = 0.0
Identities = 971/971 (100%), Positives = 971/971 (100%)
Query: 1 MATVRASLRGALLLLLAVAGVAEVAGGLAPGSAGALCCNHSKDNQMCRDVCEQIFSSKSE 60
MATVRASLRGALLLLLAVAGVAEVAGGLAPGSAGALCCNHSKDNQMCRDVCEQIFSSKSE
Sbjct: 1 MATVRASLRGALLLLLAVAGVAEVAGGLAPGSAGALCCNHSKDNQMCRDVCEQIFSSKSE 60
Query: 61 SRLKHLLQRAPDYCPETMVEIWNCMNSSLPGVFKKSDGWVGLGCCELAIALECRQACKQA 120
SRLKHLLQRAPDYCPETMVEIWNCMNSSLPGVFKKSDGWVGLGCCELAIALECRQACKQA
Sbjct: 61 SRLKHLLQRAPDYCPETMVEIWNCMNSSLPGVFKKSDGWVGLGCCELAIALECRQACKQA 120
Query: 121 SSKNDISKVCRKEYENALFSCISRNEMGSVCCSYAGHHTNCREYCQAIFRTDSSPGPSQI 180
SSKNDISKVCRKEYENALFSCISRNEMGSVCCSYAGHHTNCREYCQAIFRTDSSPGPSQI
Sbjct: 121 SSKNDISKVCRKEYENALFSCISRNEMGSVCCSYAGHHTNCREYCQAIFRTDSSPGPSQI 180
Query: 181 KAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDHACQNACKRILMSKKTEM 240
KAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDHACQNACKRILMSKKTEM
Sbjct: 181 KAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDHACQNACKRILMSKKTEM 240
Query: 241 EIVDGLIEGCKTQPLPQDPLWQCFLESSQSVHPGVTVHPPPSTGLDGAKLHCCSKANTST 300
EIVDGLIEGCKTQPLPQDPLWQCFLESSQSVHPGVTVHPPPSTGLDGAKLHCCSKANTST
Sbjct: 241 EIVDGLIEGCKTQPLPQDPLWQCFLESSQSVHPGVTVHPPPSTGLDGAKLHCCSKANTST 300
Query: 301 CRELCTKLYSMSWGNTQSWQEFDRFCEYNPVEVSMLTCLADVREPCQLGCRNLTYCTNFN 360
CRELCTKLYSMSWGNTQSWQEFDRFCEYNPVEVSMLTCLADVREPCQLGCRNLTYCTNFN
Sbjct: 301 CRELCTKLYSMSWGNTQSWQEFDRFCEYNPVEVSMLTCLADVREPCQLGCRNLTYCTNFN 360
Query: 361 NRPTELFRSCNAQSDQGAMNDMKLWEKGSIKMPFINIPVLDIKKCQPEMWKAIACSLQIK 420
NRPTELFRSCNAQSDQGAMNDMKLWEKGSIKMPFINIPVLDIKKCQPEMWKAIACSLQIK
Sbjct: 361 NRPTELFRSCNAQSDQGAMNDMKLWEKGSIKMPFINIPVLDIKKCQPEMWKAIACSLQIK 420
Query: 421 PCHSKSRGSIICKSDCVEILKKCGDQNKFPEDHTAESICELLSPTDDLKNCIPLDTYLRP 480
PCHSKSRGSIICKSDCVEILKKCGDQNKFPEDHTAESICELLSPTDDLKNCIPLDTYLRP
Sbjct: 421 PCHSKSRGSIICKSDCVEILKKCGDQNKFPEDHTAESICELLSPTDDLKNCIPLDTYLRP 480
Query: 481 STLGNIVEEVTHPCNPNPCPANELCEVNRKGCPSGDPCLPYFCVQGCKLGEASDFIVRQG 540
STLGNIVEEVTHPCNPNPCPANELCEVNRKGCPSGDPCLPYFCVQGCKLGEASDFIVRQG
Sbjct: 481 STLGNIVEEVTHPCNPNPCPANELCEVNRKGCPSGDPCLPYFCVQGCKLGEASDFIVRQG 540
Query: 541 TLIQVPSSAGEVGCYKICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCNV 600
TLIQVPSSAGEVGCYKICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCNV
Sbjct: 541 TLIQVPSSAGEVGCYKICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCNV 600
Query: 601 CSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVG 660
CSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVG
Sbjct: 601 CSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVG 660
Query: 661 LQDHQFEFGSCMSKDPCNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLACDQVQ 720
LQDHQFEFGSCMSKDPCNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLACDQVQ
Sbjct: 661 LQDHQFEFGSCMSKDPCNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLACDQVQ 720
Query: 721 DPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGHNGETYSSVCAAYSDRVA 780
DPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGHNGETYSSVCAAYSDRVA
Sbjct: 721 DPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGHNGETYSSVCAAYSDRVA 780
Query: 781 VDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGCKPIIPPGACCPLCAGMLRVLFDKEK 840
VDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGCKPIIPPGACCPLCAGMLRVLFDKEK
Sbjct: 781 VDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGCKPIIPPGACCPLCAGMLRVLFDKEK 840
Query: 841 LDTIAKVTNKKPITVLEILQKIRMHVSVPQCDVFGYFSIESEIVILIIPVDHYPKALQIE 900
LDTIAKVTNKKPITVLEILQKIRMHVSVPQCDVFGYFSIESEIVILIIPVDHYPKALQIE
Sbjct: 841 LDTIAKVTNKKPITVLEILQKIRMHVSVPQCDVFGYFSIESEIVILIIPVDHYPKALQIE 900
Query: 901 ACNKEAEKIESLINSDSPTLASHVPLSALIISQVQVSSSVPSAGVRARPSCHSLLLPLSL 960
ACNKEAEKIESLINSDSPTLASHVPLSALIISQVQVSSSVPSAGVRARPSCHSLLLPLSL
Sbjct: 901 ACNKEAEKIESLINSDSPTLASHVPLSALIISQVQVSSSVPSAGVRARPSCHSLLLPLSL 960
Query: 961 GLALHLLWTYN 971
GLALHLLWTYN
Sbjct: 961 GLALHLLWTYN 971
>gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]
Length = 814
Score = 74.3 bits (181), Expect = 5e-13
Identities = 93/371 (25%), Positives = 127/371 (34%), Gaps = 84/371 (22%)
Query: 489 EVTHPCNPNPCPANELCEVNRKGCPSGDPCLPYFCVQGCKLG-----EASDFIVRQGTLI 543
E T CN PCP R CP C P+ C GC E F+ +
Sbjct: 163 EGTITCNQKPCP--------RGPCPEPGACCPH-CKPGCDYEGQLYEEGVTFLSSSNPCL 213
Query: 544 QVPSSAGEVGCYKICSCGQSGLLENCMEM-HCIDLQKSCIVGGKRKSHGTSFSID---CN 599
Q V C + C S E + HC + C GG HG ++ C
Sbjct: 214 QCTCLRSRVRCMAL-KCPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCR 272
Query: 600 VCSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCV 659
+C C G++ C R C S R G C D C NGR + S V
Sbjct: 273 ICRCLEGHIQCRQRECAS--LCPYPARPLPGTCCPVCDG----CFLNGREHRSG---EPV 323
Query: 660 GLQDH----QFEFGSCMSKD-PCNPNPCQKNQR----CIPKPQVC---------LTTF-- 699
G D + GS + PC P PC+ + C P C TF
Sbjct: 324 GSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRL 383
Query: 700 -DKFGCSQYECVPRQLACDQVQDPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATE 758
++ C + C +++C++ + PV C L G+ L
Sbjct: 384 QERGLCVRCSCQAGEVSCEEQECPVTP---------CALPASGRQLC------------- 421
Query: 759 PVCGHNGETYSSVCAAYSDRVAVDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGCK-P 817
P C +GE ++ V + D + V +C +V CP A C+ P
Sbjct: 422 PACELDGEEFAE---------GVQWEPDGRPCTACVCQDGVPKCGAVLCPP---APCQHP 469
Query: 818 IIPPGACCPLC 828
PPGACCP C
Sbjct: 470 TQPPGACCPSC 480
Score = 45.4 bits (106), Expect = 3e-04
Identities = 66/293 (22%), Positives = 90/293 (30%), Gaps = 73/293 (24%)
Query: 560 CGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSID-CNVCSCFAGNLVCSTRLCLSE 618
CG L +C + C G+ +G +FS D C C C G + C+ + C
Sbjct: 126 CGPQAHLPHC---------RGCSQNGQTYGNGETFSPDACTTCRCLEGTITCNQKPCPRG 176
Query: 619 HSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSA---------CIARCVGLQDHQFEFG 669
E P C P C G+ Y C+ +C L+
Sbjct: 177 PCPE---------PGACCPHCKPGCDYEGQLYEEGVTFLSSSNPCL-QCTCLRSRVRCMA 226
Query: 670 SCMSKDPCNPNPCQKNQRCIPKPQVCLT-----------TFDKFGCSQYECVPRQLACDQ 718
PC P P + C P Q C T C C+ + C Q
Sbjct: 227 LKCPPSPC-PEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQ 285
Query: 719 VQDPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGHNGETYSSVCAAYSDR 778
E +LC R G C P C C NG + S S
Sbjct: 286 ----------RECASLCPYPAR----PLPGTCCPVCDG----CFLNGREHRSGEPVGSG- 326
Query: 779 VAVDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGCK-PIIPPGACCPLCAG 830
D C+ + +C + CP + C+ P PG CCP+C G
Sbjct: 327 ---DPCSHCRCA------NGSVQCEPLPCPPV---PCRHPGKIPGQCCPVCDG 367
Score = 44.7 bits (104), Expect = 4e-04
Identities = 78/362 (21%), Positives = 113/362 (31%), Gaps = 73/362 (20%)
Query: 494 CNPNPCP---ANELCEVNRKGCPSGDPCLPYFCVQGCKLGEASDFIVRQ-GTLIQVPSSA 549
C P PCP ++ + CP D C QG + F +++ G ++ A
Sbjct: 341 CEPLPCPPVPCRHPGKIPGQCCPVCDGCE----YQGHQYQSQETFRLQERGLCVRCSCQA 396
Query: 550 GEVGCYKICSCGQSGLLENCMEMHCI------DLQKSCIVGGKRKSHGTSFSID---CNV 600
GEV C + + C C L +C + G+ + G + D C
Sbjct: 397 GEVSCEE----------QECPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTA 446
Query: 601 CSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVG 660
C C G C LC P C P P AC C
Sbjct: 447 CVCQDGVPKCGAVLCP---------------PAPCQHPTQP---------PGACCPSCDS 482
Query: 661 LQDHQFEFGSCMS----KDPCNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLAC 716
H + + + PC+ CQ TT + +C PR C
Sbjct: 483 CTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDC 542
Query: 717 DQVQDPVCDTDHMEH-NNLCT--LYQRGKSLSYKGPCQPFCRATEPVCGHNGETYSSVCA 773
++ D + H + C Q G + PC P P+ G S CA
Sbjct: 543 ILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPC-PRAPCAHPLPGTCCPNDCSGCA 601
Query: 774 ----AYSDRVAVDYYGD-CQAVGVLSEHSS--VAECASVKCPSLLAAGCKPIIPPGACCP 826
Y + D C+ LS + C + CP +P++ PG CCP
Sbjct: 602 FGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCP-------EPVLLPGECCP 654
Query: 827 LC 828
C
Sbjct: 655 QC 656
Score = 42.7 bits (99), Expect = 0.002
Identities = 59/254 (23%), Positives = 78/254 (30%), Gaps = 78/254 (30%)
Query: 581 CIVGGKRKSHGTSF---SIDCNVCSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCAD 637
C GGK G F S C +C C +GN+ C R C+ E LP C
Sbjct: 600 CAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEP-----VLLPGECCP 654
Query: 638 QFVPVCGQNGRTYPSACIARCVGLQDHQFEFGSCMSKDPCNPNPCQKNQRCIPKPQVCLT 697
Q G P A AR HQ F DPC +RC+
Sbjct: 655 QCPAAPAPAGCPRPGAAHAR------HQEYFSP--PGDPC--------RRCL-------- 690
Query: 698 TFDKFGCSQYECVPRQLACDQVQDPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRAT 757
C+ ++C ++ P H +GPC P C
Sbjct: 691 -----------CLDGSVSCQRLPCPPAPCAHPR----------------QGPCCPSCDG- 722
Query: 758 EPVCGHNGETYSSVCAAYSDRVAVDYYGDCQAVGVLSEHSSVAECASVKC-PSLLAAGCK 816
C + G+ ++S G+ + H + SV C P A
Sbjct: 723 ---CLYQGKEFAS--------------GERFPSPTAACHLCLCWEGSVSCEPKACAPALC 765
Query: 817 PIIPPGACCPLCAG 830
P G CCP C G
Sbjct: 766 PFPARGDCCPDCDG 779
Score = 39.3 bits (90), Expect = 0.018
Identities = 47/187 (25%), Positives = 64/187 (34%), Gaps = 42/187 (22%)
Query: 645 QNGRTYPSACIARCVGLQDHQFEFGSCMSKDPCNPNPCQKNQRCIPKPQVCLTTFDKFGC 704
+ R P AC A CV QD G C C +N + + TF C
Sbjct: 105 EGARWEPDACTA-CV-CQDGAAHCGPQAHLPHCRG--CSQNGQTYGNGE----TFSPDAC 156
Query: 705 SQYECVPRQLACDQVQDPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGHN 764
+ C+ + C+Q P RG G C P C+ P C +
Sbjct: 157 TTCRCLEGTITCNQKPCP-----------------RGPCPE-PGACCPHCK---PGCDYE 195
Query: 765 GETYSSVCAAYSDRVAVDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGC-KPIIPPGA 823
G+ Y S C L S C ++KCP + C +P++ PG
Sbjct: 196 GQLYEEGVTFLSSS------NPCLQCTCLR---SRVRCMALKCPP---SPCPEPVLRPGH 243
Query: 824 CCPLCAG 830
CCP C G
Sbjct: 244 CCPTCQG 250
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 64.3 bits (155), Expect = 5e-10
Identities = 94/415 (22%), Positives = 135/415 (32%), Gaps = 98/415 (23%)
Query: 454 TAESICELLSPTDDLKNCIPLDTYLRPSTLGNIVEEVTHPCNPNPCPANELCEVNRKG-- 511
+ E++ + L PT L C +E + C PCP LC G
Sbjct: 787 SGETLPDPLDPTCSLCTC----------------QEGSMRCQKKPCPP-ALCPHPSPGPC 829
Query: 512 -CPSGDPCLPYFCVQGCKLGEASDFIVRQGTLIQVPSSAGEVGCYKICSCGQSGLLENCM 570
CP CL QG + + +F G+ AG+V C ++ L+
Sbjct: 830 FCPVCHSCLS----QGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTE 885
Query: 571 EMHCIDLQKSCIVGGKRKSHGTSF---SIDCNVCSCFAGNLVCSTRLCLSEHSSEDDRRT 627
C + C+ G+ G+ + C+ C C G + C+ C+S S R+
Sbjct: 886 RGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCIS--SCAQPRQG 943
Query: 628 FTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFGSCMSKDPCN-----PNP- 681
C+D C GR Y F+ G+ DPC P P
Sbjct: 944 PHDCCPQCSD-----CEHEGRKYEPG----------ESFQPGA----DPCEVCICEPQPE 984
Query: 682 -----------------CQKNQRCIPKPQVCLTTFDKFGCSQY--ECVPRQLACDQVQDP 722
C +Q P PQ C T C++ C L +
Sbjct: 985 GPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPT-----CAEALSNCSEGLLGSELAPPD 1039
Query: 723 VCDTDHMEHNNLCTLYQRGKSLSYK--------GPCQPFCRATEPVCGHNGETYSSVCAA 774
C T + ++Q LS G C P CRA C H G +S
Sbjct: 1040 PCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVAS---- 1095
Query: 775 YSDRVAVDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGCK-PIIPPGACCPLC 828
+R VD C + + C S +C L K P + PG+CCP C
Sbjct: 1096 -GERWTVDTCTSCSCM------AGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRC 1143
Score = 58.5 bits (140), Expect = 3e-08
Identities = 74/296 (25%), Positives = 105/296 (35%), Gaps = 71/296 (23%)
Query: 559 SCGQSGLLENCMEM-HCIDLQKSCIVGGKRKSHGTSFSID---CNVCSCFAGNLVCSTRL 614
SC + LE+C C + C GG HG ++ C +C C G++ C R
Sbjct: 172 SCSELNCLESCTPPGECCPI--CCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229
Query: 615 CLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQDH----QFEFGS 670
C S R G C D C NGR + S VG D + GS
Sbjct: 230 CAS--LCPYPARPLPGTCCPVCDG----CFLNGREHRSG---EPVGSGDPCSHCRCANGS 280
Query: 671 CMSKD-PCNPNPCQKNQR----CIPKPQVC---------LTTF---DKFGCSQYECVPRQ 713
+ PC P PC+ + C P C TF ++ C + C +
Sbjct: 281 VQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGE 340
Query: 714 LACDQVQDPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGHNGETYSSVCA 773
++C++ + PV C L G+ L P C +GE ++
Sbjct: 341 VSCEEQECPVTP---------CALPASGRQLC-------------PACELDGEEFAE--- 375
Query: 774 AYSDRVAVDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGCK-PIIPPGACCPLC 828
V + D + V +C +V CP A C+ P PPGACCP C
Sbjct: 376 ------GVQWEPDGRPCTACVCQDGVPKCGAVLCPP---APCQHPTQPPGACCPSC 422
Score = 48.5 bits (114), Expect = 3e-05
Identities = 70/279 (25%), Positives = 89/279 (31%), Gaps = 72/279 (25%)
Query: 581 CIVGGKRKSHGTSF---SIDCNVCSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCAD 637
C GGK G F S C +C C +GN+ C R C+ E LP C
Sbjct: 542 CAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEP-----VLLPGECCP 596
Query: 638 QFVPVCG-----------QNGRTYPSACIARCVGLQDHQFEFGSCMSKDPCNPNPCQKNQ 686
Q G Q + P RC+ L SC + PC P PC +
Sbjct: 597 QCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSV----SC-QRLPCPPAPCAHPR 651
Query: 687 R--CIPKPQVCLTTFDKFGCSQYECVPRQLACDQVQDPVCDTDHMEHNNLCTLYQRGKSL 744
+ C P CL +F + P AC +LC ++ S
Sbjct: 652 QGPCCPSCDGCLYQGKEFASGERFPSP-TAAC----------------HLCLCWEGSVSC 694
Query: 745 SYK------------GPCQPFCRATEPVCGHNGETYSSVCAAYSDRVAVDYYGDCQAVGV 792
K G C P C C + GE+Y S++ D C
Sbjct: 695 EPKACAPALCPFPARGDCCPDCDG----CEYLGESY------LSNQEFPDPREPCNLCTC 744
Query: 793 LSEHSSVAECASVKCPSLLAAGCK-PIIPPGACCPLCAG 830
L C C GC P+IP G CCP C G
Sbjct: 745 L---GGFVTCGRRPCE---PPGCSHPLIPSGHCCPTCQG 777
Score = 45.1 bits (105), Expect = 3e-04
Identities = 97/452 (21%), Positives = 139/452 (30%), Gaps = 119/452 (26%)
Query: 421 PCHSKSRGSIICKSDCVEIL---KKCGDQNKFPEDHTAESICELLSPTDDL--KNCIPLD 475
PC G+ C +DC K+ FP +C LS + C+PL
Sbjct: 525 PCAHPLPGTC-CPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLP 583
Query: 476 TYLRPSTLGNIVEEVTHPCNPNPCPANELCEVNRKGCPSGDPCLPYFCVQGCKLGEASDF 535
G + P P P P GDPC C+ G
Sbjct: 584 CPEPVLLPGECCPQCPAPAGC-PRPGAAHARHQEYFSPPGDPCRRCLCLDG--------- 633
Query: 536 IVRQGTLIQVPSSAGEVGCYKI------CSCGQSGLLENCMEMHCIDLQKSCIVGGKRKS 589
V C ++ C+ + G C C+ GK +
Sbjct: 634 ---------------SVSCQRLPCPPAPCAHPRQG--------PCCPSCDGCLYQGKEFA 670
Query: 590 HGTSF---SIDCNVCSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQN 646
G F + C++C C+ G++ C + C R G C D C
Sbjct: 671 SGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPAR----GDCCPDCDG----CEYL 722
Query: 647 GRTYPS----------ACIARCVGLQDHQFEFGSCMSKDPCNPNPCQK----NQRCIPKP 692
G +Y S + C+G F +C + PC P C + C P
Sbjct: 723 GESYLSNQEFPDPREPCNLCTCLG------GFVTC-GRRPCEPPGCSHPLIPSGHCCPTC 775
Query: 693 QVCLTTFDKFGCSQYECVPRQLACDQVQDPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQP 752
Q C + + E +P L DP C +LCT Q G K PC P
Sbjct: 776 QGC--RYHGVTTASGETLPDPL------DPTC--------SLCTC-QEGSMRCQKKPCPP 818
Query: 753 -----------FCRATEPVCGHNGETYSSVCAAYSDRVAVDYYGDCQAVGVLSEHSSVAE 801
FC PVC +S + + ++ G + +
Sbjct: 819 ALCPHPSPGPCFC----PVC------HSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVS 868
Query: 802 CASVKCPSLLAAGCK-PIIPPGACCPLCAGML 832
C ++CP L CK + G+CCP C G L
Sbjct: 869 CVRLQCPPL---PCKLQVTERGSCCPRCRGCL 897
Score = 42.7 bits (99), Expect = 0.002
Identities = 72/291 (24%), Positives = 105/291 (36%), Gaps = 68/291 (23%)
Query: 573 HCIDLQKSCIVGGKRKSHGTSFS--ID--CNVCSCFAGNLVCSTRLC---LSEHSSEDDR 625
HC + C G + G + +D C++C+C G++ C + C L H S
Sbjct: 770 HCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSPG-- 827
Query: 626 RTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQD-HQFE--FGSC----------- 671
PC C PVC +C+++ QD +FE GSC
Sbjct: 828 ------PCFC-----PVC--------HSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVS 868
Query: 672 MSKDPCNPNPCQ----KNQRCIPKPQVCLTTFDKFGCSQYECVPRQLACDQV--QDPVCD 725
+ C P PC+ + C P+ + CL ++ VP AC + V
Sbjct: 869 CVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS-RWVPPDSACSSCVCHEGVVT 927
Query: 726 TDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGHNGETYSSVCAAYSDRVAVDYYG 785
++ + C ++G C P C C H G Y S + D
Sbjct: 928 CARIQCISSCAQPRQGPH-----DCCPQCSD----CEHEGRKYEP---GESFQPGADPCE 975
Query: 786 DCQAVGVLSEHSSVAECASVKCPSLLAAGCKP--IIPPGA--CCPLCAGML 832
C E C +CPSL+ GC P ++PPG CCP CA L
Sbjct: 976 VC-ICEPQPEGPPSLRCHRRQCPSLV--GCPPSQLLPPGPQHCCPTCAEAL 1023
Score = 35.0 bits (79), Expect = 0.34
Identities = 47/187 (25%), Positives = 67/187 (35%), Gaps = 41/187 (21%)
Query: 645 QNGRTYPSACIARCVGLQDHQFEFGSCMSKDPCNPNPCQKNQRCIPKPQVCLTTFDKFGC 704
+ R P AC A CV QD G C C +N + + TF C
Sbjct: 105 EGARWEPDACTA-CV-CQDGAAHCGPQAHLPHCRG--CSQNGQTYGNGE----TFSPDAC 156
Query: 705 SQYECVPRQLACDQVQDPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGHN 764
+ C+ + C Q P C E N L +S + G C P C +
Sbjct: 157 TTCRCLTGAVQC---QGPSCS----ELNCL-------ESCTPPGECCPICCTEGGSHWEH 202
Query: 765 GETYSSVCAAYSDRVAVDYYGD-CQAVGVLSEHSSVAECASVKCPSLLAAGCKPIIPPGA 823
G+ +++ GD C+ L H +C +C SL +P+ PG
Sbjct: 203 GQEWTTP-------------GDPCRICRCLEGH---IQCRQRECASLCPYPARPL--PGT 244
Query: 824 CCPLCAG 830
CCP+C G
Sbjct: 245 CCPVCDG 251
Score = 35.0 bits (79), Expect = 0.34
Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 11/79 (13%)
Query: 579 KSCIVGGKRKSHGTSFSID-CNVCSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCAD 637
+SC+ G+ + G +++D C CSC AG + C ++ C D + P +C
Sbjct: 1084 QSCVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALS--PGSCCP 1141
Query: 638 QFVPVCGQNGRTYPSACIA 656
+ +P P++C+A
Sbjct: 1142 RCLP--------RPASCMA 1152
Score = 33.9 bits (76), Expect = 0.76
Identities = 58/275 (21%), Positives = 78/275 (28%), Gaps = 95/275 (34%)
Query: 560 CGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSID-CNVCSCFAGNLVCSTRLCLSE 618
CG L +C + C G+ +G +FS D C C C G + C C
Sbjct: 126 CGPQAHLPHC---------RGCSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSE- 175
Query: 619 HSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFGSCMSK--DP 676
NC + P P C C +E G + DP
Sbjct: 176 --------------LNCLESCTP---------PGECCPICCTEGGSHWEHGQEWTTPGDP 212
Query: 677 CNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLACDQVQDPVCDTDHMEHNNLCT 736
C ++C C Q EC +LC
Sbjct: 213 C---------------RICRCLEGHIQCRQRECA----------------------SLCP 235
Query: 737 LYQRGKSLSYKGPCQPFCRATEPVCGHNGETYSSVCAAYSDRVAVDYYGDCQAVGVLSEH 796
R G C P C C NG + S S D C+
Sbjct: 236 YPAR----PLPGTCCPVCDG----CFLNGREHRSGEPVGSG----DPCSHCRCA------ 277
Query: 797 SSVAECASVKCPSLLAAGCK-PIIPPGACCPLCAG 830
+ +C + CP + C+ P PG CCP+C G
Sbjct: 278 NGSVQCEPLPCPPV---PCRHPGKIPGQCCPVCDG 309
Score = 32.3 bits (72), Expect = 2.2
Identities = 33/127 (25%), Positives = 47/127 (37%), Gaps = 32/127 (25%)
Query: 574 CIDLQKSCIVGGKRKSHGTSFS---IDCNVCSCFAGNLVCSTRLCLSEHSSEDDRRTFTG 630
C SC + ++G +F+ C+ C C G + CS C
Sbjct: 418 CCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDC--------------- 462
Query: 631 LPCNCADQFVPVCGQNGRTYPSACIARCVG--LQDHQFEFGSCMS--KDPCNPNPCQK-N 685
P CA Q+G P C RC L++ F G S +DPC CQ+ +
Sbjct: 463 PPTTCARP------QSG---PGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGH 513
Query: 686 QRCIPKP 692
C P+P
Sbjct: 514 AHCQPRP 520
>gi|54873613 agrin [Homo sapiens]
Length = 2045
Score = 63.5 bits (153), Expect = 9e-10
Identities = 84/364 (23%), Positives = 124/364 (34%), Gaps = 86/364 (23%)
Query: 507 VNRKGCPSGDPCLPYFCVQGCKLGEASDFIVRQGTLIQVPSSAGEVGCYKICSCGQSGLL 566
++R C S DPC C G ++D G A G + CG G
Sbjct: 237 LSRGPCGSRDPCSNVTCSFGSTCARSAD-----GLTASCLCPATCRGAPEGTVCGSDGA- 290
Query: 567 ENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCNVCSCFAGNLVCSTRLCLSEHSSEDDRR 626
C L+++C ++++ F C+ C G L +R C + R
Sbjct: 291 --DYPGECQLLRRAC---ARQENVFKKFDGPCDPCQ---GALPDPSRSCRVNPRTR--RP 340
Query: 627 TFTGLPCNCADQFVPVCGQNGRTYPSACI----ARCVGLQDHQFEFGSCMSKDPCNPNPC 682
P +C + PVCG +G TY + C+ GL + G C +D C P PC
Sbjct: 341 EMLLRPESCPARQAPVCGDDGVTYENDCVMGRSGAARGLLLQKVRSGQCQGRDQC-PEPC 399
Query: 683 QKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLACDQVQDPVCDTDHMEHNNLC------T 736
+ N C+ + + C ++ CD PVC D +++ C
Sbjct: 400 RFNAVCLSRR------------GRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAEC 447
Query: 737 LYQRGKSLSYKGPC-----------------------QPFCRAT-------EPVCGHNGE 766
QR ++GPC Q C +PVCG +G
Sbjct: 448 RQQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLYDPVCGSDGV 507
Query: 767 TYSSVCAAYSDRVAV------------DYYGDCQAVGVLSEHSSVAECASVKCPSLLAAG 814
TY S C + + D G C+ G L E AE CPS A
Sbjct: 508 TYGSACELEATACTLGREIQVARKGPCDRCGQCR-FGALCE----AETGRCVCPSECVAL 562
Query: 815 CKPI 818
+P+
Sbjct: 563 AQPV 566
Score = 57.0 bits (136), Expect = 8e-08
Identities = 60/228 (26%), Positives = 84/228 (36%), Gaps = 53/228 (23%)
Query: 635 CADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFGSCMSKDPCN--PNPCQKNQRCIPKP 692
C + PVC Q+GRTY S C + + Q + PC+ P+PC Q
Sbjct: 421 CDGAYRPVCAQDGRTYDSDCWRQ--QAECRQQRAIPSKHQGPCDQAPSPCLGVQCAFG-- 476
Query: 693 QVCLTTFDKFGCSQYECVPRQLACDQVQDPVCDTDHMEHNNLCTL------YQRGKSLSY 746
T K G + EC+ AC + DPVC +D + + + C L R ++
Sbjct: 477 ---ATCAVKNGQAACECLQ---ACSSLYDPVCGSDGVTYGSACELEATACTLGREIQVAR 530
Query: 747 KGPCQ--------PFCRA--------------TEPVCGHNGETYSSVC------AAYSDR 778
KGPC C A +PVCG +G TY S C +
Sbjct: 531 KGPCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQIS 590
Query: 779 VAVDYYGDCQAVG-VLSEHSSVAECASVKCPSLLAAGCKPIIPPGACC 825
+ V G C+ G + +V CP C+ PPG C
Sbjct: 591 LHVASAGPCETCGDAVCAFGAVCSAGQCVCPR-----CEH-PPPGPVC 632
Score = 42.4 bits (98), Expect = 0.002
Identities = 43/152 (28%), Positives = 59/152 (38%), Gaps = 31/152 (20%)
Query: 632 PCNCADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFGSCMSKDPCNPNPCQKNQRCIPK 691
P C PVCG +G TYPS C+ V HQ +S + PC
Sbjct: 556 PSECVALAQPVCGSDGHTYPSECMLH-VHACTHQ------ISLHVASAGPC--------- 599
Query: 692 PQVCLTTFDKFG--CSQYECV-PRQLACDQ-VQDPVCDTDHMEHNNLC------TLYQRG 741
+ C FG CS +CV PR C+ PVC +D + + + C L Q
Sbjct: 600 -ETCGDAVCAFGAVCSAGQCVCPR---CEHPPPGPVCGSDGVTYGSACELREAACLQQTQ 655
Query: 742 KSLSYKGPC-QPFCRATEPVCGHNGETYSSVC 772
+ GPC Q C + G +G+ +C
Sbjct: 656 IEEARAGPCEQAECGSGGSGSGEDGDCEQELC 687
Score = 42.0 bits (97), Expect = 0.003
Identities = 41/177 (23%), Positives = 58/177 (32%), Gaps = 49/177 (27%)
Query: 635 CADQFVPVCGQNGRTYPSAC-IARCVGLQDHQFEF---GSCMSKDPCNPNPCQKNQRCIP 690
C PVCG + TY + C + R Q + G C S+DPC+ C
Sbjct: 202 CPSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPCGSRDPCSNVTCSFG----- 256
Query: 691 KPQVCLTTFDKFGCSQYECVPRQLACDQVQDPVCDTDHMEHNNLCTLYQRGKS------L 744
C + D S C+ + VC +D ++ C L +R +
Sbjct: 257 --STCARSADGLTAS---CLCPATCRGAPEGTVCGSDGADYPGECQLLRRACARQENVFK 311
Query: 745 SYKGPCQP----------FCRAT-------------------EPVCGHNGETYSSVC 772
+ GPC P CR PVCG +G TY + C
Sbjct: 312 KFDGPCDPCQGALPDPSRSCRVNPRTRRPEMLLRPESCPARQAPVCGDDGVTYENDC 368
Score = 41.6 bits (96), Expect = 0.004
Identities = 44/171 (25%), Positives = 62/171 (36%), Gaps = 54/171 (31%)
Query: 635 CADQFVPVCGQNGRTYPSAC----IARCVGLQDHQFEFGSCMSKDPCNPNPCQKNQRCIP 690
C+ + PVCG +G TY SAC A +G + G C D C C+ C
Sbjct: 494 CSSLYDPVCGSDGVTYGSACELEATACTLGREIQVARKGPC---DRC--GQCRFGALCEA 548
Query: 691 KPQVCLTTFDKFGCSQYECVPRQLACDQVQDPVCDTDH-------MEHNNLCTLYQRGKS 743
+ C+ + C + PVC +D M H + CT +Q
Sbjct: 549 ETGRCVCPSE---------------CVALAQPVCGSDGHTYPSECMLHVHACT-HQISLH 592
Query: 744 LSYKGPCQ----------PFCRATE------------PVCGHNGETYSSVC 772
++ GPC+ C A + PVCG +G TY S C
Sbjct: 593 VASAGPCETCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSAC 643
Score = 35.0 bits (79), Expect = 0.34
Identities = 28/109 (25%), Positives = 41/109 (37%), Gaps = 20/109 (18%)
Query: 675 DPCNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLACDQVQDPVCDTDHMEHNNL 734
D C C C P + G + CV ++ C V PVC +D ++N
Sbjct: 170 DACRGMLCGFGAVCEPNAE---------GPGRASCVCKKSPCPSVVAPVCGSDASTYSNE 220
Query: 735 CTL------YQRGKSLSYKGPCQPFCRATEPVCGHNGETYSSVCAAYSD 777
C L QR L +GPC + C + ++ S CA +D
Sbjct: 221 CELQRAQCSQQRRIRLLSRGPC-----GSRDPCSNVTCSFGSTCARSAD 264
Score = 32.3 bits (72), Expect = 2.2
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 9/78 (11%)
Query: 752 PFCRATEPVCGHNGETYSSVC------AAYSDRVAVDYYGDCQAVGVLSEHSSVAECASV 805
P AT+ VCG +G TY + C ++++ G CQ S H + A +V
Sbjct: 929 PEANATK-VCGSDGVTYGNECQLKTIACRQGLQISIQSLGPCQEAVAPSTHPTSAS-VTV 986
Query: 806 KCPSLLAAGCKPIIPPGA 823
P LL + P PPGA
Sbjct: 987 TTPGLLLSQALP-APPGA 1003
>gi|148727298 keratin associated protein 10-6 [Homo sapiens]
Length = 365
Score = 55.5 bits (132), Expect = 2e-07
Identities = 85/354 (24%), Positives = 114/354 (32%), Gaps = 63/354 (17%)
Query: 487 VEEVTHPCNPNPCPANELCEVNRKGCPSGDPCLPYFCVQG-CKLGEASDFIVRQGTLIQV 545
V V+ PC P C + + GC S C P C Q C+L + +Q V
Sbjct: 60 VSRVSSPCCPVTCEPSPC----QSGCTSS--CTPSCCQQSSCQLACCASSPCQQACC--V 111
Query: 546 PSSAGEVGCYKICS----CGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCN-V 600
P V C +C CG S C + C Q +C + + C V
Sbjct: 112 PVCCKTVCCKPVCCVSVCCGDSSC---CQQSSC---QSACCTSSPCQQ-ACCVPVCCKPV 164
Query: 601 CSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCN--CADQFVPVCGQNGRTYPSACIARC 658
CS + + C C+S SS + PC C P C Q P+ C
Sbjct: 165 CSGISSSC-CQQSSCVSCVSSPCCQAVCEPSPCQSGCTSSCTPSCCQQSSCQPTCC---- 219
Query: 659 VGLQDHQFEFGSCMSKDPCNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLACDQ 718
+ PC C C+P V + D C Q Q +C
Sbjct: 220 --------------TSSPCQ-QACCVPVCCVPVCCVPTCSEDSSSCCQ------QSSCQ- 257
Query: 719 VQDPVCDTDHMEHNNLCTLYQRGKSLS--YKGPCQPFCRATEPVCGHNGETYSSVCAAYS 776
P C T + C G S S + CQP C C + S +C
Sbjct: 258 ---PACCTSSPCQHACCVPVCSGASTSCCQQSSCQPACCTAS--CCRPSSSVSLLCHPVC 312
Query: 777 DRVAVDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGCKPIIPPGACCPLCAG 830
C A + S C + C SLL C+P+ AC LC+G
Sbjct: 313 KSTCCVPVPSCGASASSCQPSC---CRTASCVSLL---CRPMCSRPACYSLCSG 360
>gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]
Length = 1036
Score = 52.4 bits (124), Expect = 2e-06
Identities = 58/259 (22%), Positives = 94/259 (36%), Gaps = 76/259 (29%)
Query: 584 GGKRKSHGTSFSID-CNVCSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPV 642
GG+ G +++ID C C+C +G ++C T +C P+
Sbjct: 683 GGEYFVEGETWNIDSCTQCTCHSGRVLCETEVC------------------------PPL 718
Query: 643 CGQNGRTYPSACIARCVGLQDHQFEFGSCMSKDPCNPNPCQKNQRCI------PKPQVCL 696
QN +C +C F +S++ PN C+ ++ I KP VC
Sbjct: 719 LCQNPSRTQDSCCPQCT-----DQPFRPSLSRNNSVPNYCKNDEGDIFLAAESWKPDVCT 773
Query: 697 TTFDKFGCSQYECVPRQLACDQVQDPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFC-R 755
+ C+ ++C + C + + KG C P+C
Sbjct: 774 SCI---------CIDSVISC--------------FSESCPSVSCERPVLRKGQCCPYCIE 810
Query: 756 ATEP---VCGHNGETYSSVCAAYSDRVAVDYYGDCQAVGVLSEHSSVAECASVKCPSLLA 812
T P VC +G+ Y A +R +D C + C++V CP L
Sbjct: 811 DTIPKKVVCHFSGKAY-----ADEERWDLDSCTHCYCL------QGQTLCSTVSCPPLPC 859
Query: 813 AGCKPIIPPGACCPLCAGM 831
+PI G+CCP+C M
Sbjct: 860 V--EPINVEGSCCPMCPEM 876
Score = 40.8 bits (94), Expect = 0.006
Identities = 63/279 (22%), Positives = 93/279 (33%), Gaps = 48/279 (17%)
Query: 581 CIVGGKRKSHGTSF-SIDCNVCSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQF 639
C G +HG + DC C C G C +C +T T P +
Sbjct: 403 CYANGLILAHGDRWREDDCTFCQCVNGERHCVATVC---------GQTCTN-PVKVPGEC 452
Query: 640 VPVCGQNGRTYPSACIARCVGLQDHQFEFGSCMSKDPCNPNPCQKNQRCIPKPQVC---- 695
PVC + T + C L + C++ + N C+ Q CI ++C
Sbjct: 453 CPVCEEP--TIITVDPPACGELSNCTLTGKDCINGFKRDHNGCRTCQ-CINTEELCSERK 509
Query: 696 --LTTFDKFG-------CSQYECVPRQLACDQVQ-DPVCDTDHMEHNNLCTLYQRGK--S 743
T FG C EC PR C + D C +++ + C + + K
Sbjct: 510 QGCTLNCPFGFLTDAQNCEICECRPRPKKCRPIICDKYCPLGLLKNKHGCDICRCKKCPE 569
Query: 744 LSYKGPCQP----------FCRATEPVCGHNGETYSSVCAA---YSDRVAVDYYGDCQAV 790
LS C C+ E S C + + ++ C+
Sbjct: 570 LSCSKICPLGFQQDSHGCLICKCREASASAGPPILSGTCLTVDGHHHKNEESWHDGCREC 629
Query: 791 GVLSEHSSVAECASVKCPSLLAAGCKPIIPPGACCPLCA 829
L+ CA + CP + A P I PG CCP CA
Sbjct: 630 YCLNGREM---CALITCP--VPACGNPTIHPGQCCPSCA 663
Score = 37.4 bits (85), Expect = 0.069
Identities = 60/253 (23%), Positives = 77/253 (30%), Gaps = 100/253 (39%)
Query: 635 CADQFVPVCGQN-----GRTYPSACI---ARCVGLQDHQFEFGSCMSKDPCNPNPCQKNQ 686
C QF P C ++ G P C +RCV CNP C +
Sbjct: 179 CEVQFSPRCPEDSVLIEGYAPPGECCPLPSRCV-----------------CNPAGCLRKV 221
Query: 687 RCIP------------KPQVCLTTFDKFGCSQYECVP------RQLACDQVQDPVCDTDH 728
C P KP C C YEC P R + C VQ C D
Sbjct: 222 -CQPGNLNILVSKASGKPGEC--------CDLYECKPVFGVDCRTVECPPVQQTACPPDS 272
Query: 729 MEH------NNLCTLYQRGKSLSYKGPCQ-PFCRA------------------------- 756
E + CTL R + LS G C P C
Sbjct: 273 YETQVRLTADGCCTLPTRCECLS--GLCGFPVCEVGSTPRIVSRGDGTPGKCCDVFECVN 330
Query: 757 -TEPVCGHNGETYSSVCAAYSDRVAVDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGC 815
T+P C N Y D +D C+ G ++ A+C + C
Sbjct: 331 DTKPACVFNNVEYYD-----GDMFRMDNCRFCRCQGGVAI-CFTAQCGEINCE------- 377
Query: 816 KPIIPPGACCPLC 828
+ +P G CCP+C
Sbjct: 378 RYYVPEGECCPVC 390
>gi|154759249 keratin associated protein 10-11 [Homo sapiens]
Length = 298
Score = 51.6 bits (122), Expect = 4e-06
Identities = 64/249 (25%), Positives = 85/249 (34%), Gaps = 33/249 (13%)
Query: 598 CNVCSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIAR 657
C +C +G T C + S + T PC A VPVC + P C+
Sbjct: 62 CEPSACQSGCTSSCTPSCCQQSSCQP--ACCTSSPCQQAC-CVPVCCKTVCCKPVCCVPV 118
Query: 658 CVGLQDHQFEFGSCMSKDPCNPNPCQKNQ----RCIP---KPQVCLTTFDKFG---CSQY 707
C G SC + C P C + C+P KP C++T + C Q
Sbjct: 119 CCGAA------SSCCRQSSCQPACCASSSCQPACCVPVCCKPVCCVSTCSEDSSSCCQQS 172
Query: 708 ECVPRQLACDQVQD----PV-CDTDHMEHNNLCTLYQRGKSLSYKGP-CQPFCRATEPVC 761
C P Q PV C T + + + R S + P CQP C T C
Sbjct: 173 SCQPACCTSSSYQQACCVPVCCKTVYCKPICCVPVCSRASSSRCQQPSCQPACCTTS--C 230
Query: 762 GHNGETYSSVCAAYSDRVAVDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGCKPIIPP 821
+ S +C C A + S C C SLL C+P
Sbjct: 231 CRPSSSVSLLCHPVCRSTCCVPVSSCCAPTSSCQSSC---CRPASCVSLL---CRPASSR 284
Query: 822 GACCPLCAG 830
AC LC+G
Sbjct: 285 LACYSLCSG 293
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 49.7 bits (117), Expect = 1e-05
Identities = 52/191 (27%), Positives = 68/191 (35%), Gaps = 30/191 (15%)
Query: 459 CELLSPTDDLKNCIPLDTYLRPSTLGNIVEEVTHPCNPN---PCPANELCEVNRKGCPSG 515
C+LL T C PL + P + E+ C CPA L E R G
Sbjct: 225 CQLLKSTSVFARCHPL---VDPEPFVALCEKTLCECAGGLECACPA--LLEYARTCAQEG 279
Query: 516 ---------DPCLPYFCVQGCKLGEASDFIVRQGTLIQVPSSAGEVGCYKICSCGQSGLL 566
C P C G + + R + + E C CSC + LL
Sbjct: 280 MVLYGWTDHSACSPV-CPAGMEYRQCVSPCARTCQSLHINEMCQE-RCVDGCSCPEGQLL 337
Query: 567 ENCMEMHCIDLQKS-CIVGGKRKSHGTSFSIDCNVCSCFAGNLVCSTRLCLSE------- 618
+ + C++ + C+ GKR GTS S DCN C C +CS C E
Sbjct: 338 DEGL---CVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWICSNEECPGECLVTGQS 394
Query: 619 HSSEDDRRTFT 629
H D R FT
Sbjct: 395 HFKSFDNRYFT 405
Score = 37.7 bits (86), Expect = 0.053
Identities = 104/458 (22%), Positives = 142/458 (31%), Gaps = 116/458 (25%)
Query: 428 GSIICKSDCVEILKKCGDQNKFPE----DHTAESICELLSPTDDLKNCIPLDTYLRPSTL 483
GS + + C + + + G Q++F E DH IC LS
Sbjct: 2246 GSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLS-------------------- 2285
Query: 484 GNIVEEVTHPCNPNPCPANELCEVNRKGCPSGDPCLPYFCVQGCKLGEASDFIVRQGTLI 543
G V T PC P LCEV R + C Y CV + + L
Sbjct: 2286 GRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVSCDLPPVPHCERGLQ 2345
Query: 544 QVPSSAGEVGCYKICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCN---- 599
++ GE C+C + E C + + ++ + CN
Sbjct: 2346 PTLTNPGECRPNFTCACRK----EECKRVSPPSCPPHRLPTLRKTQCCDEYECACNCVNS 2401
Query: 600 VCSCFAGNLV--------CSTRLCLSE----HSS------------------EDDRRTFT 629
SC G L C+T CL + H S D
Sbjct: 2402 TVSCPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVM 2461
Query: 630 GL--------PC--NCADQFVPVCGQN---GRTYPSAC-IARCVGLQDHQFEFGSCMSKD 675
GL PC +C F V + GR PSAC + D Q + S S+
Sbjct: 2462 GLRVAQCSQKPCEDSCRSGFTYVLHEGECCGRCLPSACEVVTGSPRGDSQSSWKSVGSQW 2521
Query: 676 PCNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLACDQVQDPVCDTDHMEHNNLC 735
NPC N+ K +V + R ++C Q++ PVC +
Sbjct: 2522 ASPENPCLINECVRVKEEVFIQ-------------QRNVSCPQLEVPVCPS--------- 2559
Query: 736 TLYQRGKSLSYK-GPCQPFCRATE-PVCGHNGETYSSVCAAYSDRVAVDYYGDCQA---V 790
G LS K C P CR C NG V +D C+ V
Sbjct: 2560 -----GFQLSCKTSACCPSCRCERMEACMLNGTVIGP-----GKTVMIDVCTTCRCMVQV 2609
Query: 791 GVLSEHSSVAECASVKCPSLLAAGCKPIIPPGACCPLC 828
GV+S EC C + G K G CC C
Sbjct: 2610 GVISGFK--LECRKTTC-NPCPLGYKEENNTGECCGRC 2644
Score = 36.2 bits (82), Expect = 0.15
Identities = 33/109 (30%), Positives = 48/109 (44%), Gaps = 15/109 (13%)
Query: 552 VGCYKICSCGQSGLLENCMEMHCIDLQKS-CIVGGKRKSHGTSFSIDCNVCSCFAGNLVC 610
+GC C C G++ + E C+ L++ C GK + G + I CN C C C
Sbjct: 802 MGCVSGCLC-PPGMVRH--ENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNC 858
Query: 611 STRLCLSEHSSEDDRR--TFTGL----PCNCADQFVPV---CGQNGRTY 650
+ +C + S+ TF GL P C Q+V V CG N T+
Sbjct: 859 TDHVCDATCSTIGMAHYLTFDGLKYLFPGEC--QYVLVQDYCGSNPGTF 905
>gi|38490568 keratin associated protein 10-4 [Homo sapiens]
Length = 401
Score = 49.3 bits (116), Expect = 2e-05
Identities = 109/437 (24%), Positives = 141/437 (32%), Gaps = 102/437 (23%)
Query: 431 ICKSDCVEILKKC------GDQNKFPEDHTAESICELLSPTDDLKNCIPLDTYLRPSTLG 484
+C SD + C + + D ES CE P C P S +
Sbjct: 3 VCSSDLSYSSRVCLPGSCDSCSDSWQVDDCPESCCE--PPCCAPSCCAPAPCL---SLVC 57
Query: 485 NIVEEVTHPCNPNPCPANELCEVNRKGCPSGDPCLPYFCVQG-CKLGEASDFIVRQGTLI 543
V V+ PC P C + + GC S C P C Q C+L + +Q
Sbjct: 58 TPVSRVSSPCCPVTCEPSPC----QSGCTSS--CTPSCCQQSSCQLACCASSPCQQACC- 110
Query: 544 QVPSSAGEVGCYKICS----CGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCN 599
VP V C +C CG S C + C Q +C + I C
Sbjct: 111 -VPVCCKTVCCKPVCCVPVCCGDSSC---CQQSSC---QSACCTSSPCQQ-ACCVPICCK 162
Query: 600 -VCSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCN--CADQFVPVCGQNGRTYPSACI- 655
VCS + + C C+S SS + PC C P C Q P+ C
Sbjct: 163 PVCSGISSSC-CQQSSCVSCVSSPCCQAVCEPSPCQSGCISSCTPSCCQQSSCQPACCTS 221
Query: 656 -----ARCVGLQDHQF--------EFGSCMSKDPCNP-----NPCQKNQRCIP---KPQV 694
A CV + + SC + C P +PCQ+ C+P KP
Sbjct: 222 SSCQQACCVPVCCKTVCCKPVCSEDSSSCCQQSSCQPACCTSSPCQQ-ACCVPVCCKPVC 280
Query: 695 CLTTFDKFGCSQYECVPRQLACDQVQ-DPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPF 753
C CS L C Q P C CT S S +G C P
Sbjct: 281 CKPVGSVPICSGAS----SLCCQQSSCQPAC----------CT-----SSQSQQGCCVPV 321
Query: 754 CR---ATEPVCGHNGETYSSVCAAYSDRVAVDYYGDCQAVGVLSEHSSVAECASVKCPSL 810
C + PVC SS C S + A C SSV SL
Sbjct: 322 CCKPVSCVPVCSGAS---SSCCQQSSCQPA------CCTTSCCRPSSSV---------SL 363
Query: 811 LAAGCKPIIPPGACCPL 827
L C+P+ P C P+
Sbjct: 364 L---CRPVCRPACCVPV 377
Score = 38.1 bits (87), Expect = 0.040
Identities = 65/247 (26%), Positives = 82/247 (33%), Gaps = 47/247 (19%)
Query: 599 NVCSCFAGNLVCSTRLCL-SEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACI-A 656
+VCS +L S+R+CL S D P +C + P C PS C A
Sbjct: 2 SVCS---SDLSYSSRVCLPGSCDSCSDSWQVDDCPESCCEP--PCCA------PSCCAPA 50
Query: 657 RCVGLQDHQFE-FGSCMSKDPCNPNPCQKNQRCIPKPQVC------LTTFDKFGCSQYEC 709
C+ L S C P+PCQ P C L C Q C
Sbjct: 51 PCLSLVCTPVSRVSSPCCPVTCEPSPCQSGCTSSCTPSCCQQSSCQLACCASSPCQQACC 110
Query: 710 VP---RQLACDQV-QDPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFC---RATEPVCG 762
VP + + C V PVC D ++ C + PCQ C +PVC
Sbjct: 111 VPVCCKTVCCKPVCCVPVCCGD----SSCCQQSSCQSACCTSSPCQQACCVPICCKPVC- 165
Query: 763 HNGETYSSVCAAYSDRVAVDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGCKP-IIPP 821
SS C S V+ CQAV C C S + C P
Sbjct: 166 ---SGISSSCCQQSSCVSCVSSPCCQAV-----------CEPSPCQSGCISSCTPSCCQQ 211
Query: 822 GACCPLC 828
+C P C
Sbjct: 212 SSCQPAC 218
>gi|32140182 keratin associated protein 10-10 [Homo sapiens]
Length = 251
Score = 49.3 bits (116), Expect = 2e-05
Identities = 62/253 (24%), Positives = 88/253 (34%), Gaps = 53/253 (20%)
Query: 598 CNVCSCFAG---NLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSAC 654
C C C LVC+ C+S PC C P Q+G Y S+C
Sbjct: 27 CEPCCCAPAPSLTLVCTPVSCVSS-------------PC-CQTACEPSACQSG--YTSSC 70
Query: 655 IARCVGLQDHQFEFGSCMSKDPCNPNPCQKNQRCIPK---PQVCLTTFDKFGCSQYECVP 711
C ++ SC D C +PCQ+ C+P P C+ +K C C
Sbjct: 71 TTPC-------YQQSSCQP-DCCTSSPCQQ-ACCVPVCCVPVCCVPVCNKPVCFVPTCSE 121
Query: 712 RQLACDQVQD--PVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGHNGETYS 769
+C Q P C T C + KS+ Y P C C
Sbjct: 122 SSPSCCQQSSCQPTCCTSS-PCQQACCVPVCSKSVCYV----PVCSGASTSCCQQSSCQP 176
Query: 770 SVCAAY----SDRVAVDYYGDCQAV--------GVLSEHSSVAECASVKCPSLLAAGCKP 817
+ C A S V++ + C++ G + + C + C SLL C+P
Sbjct: 177 ACCTASCCRPSSSVSLLCHPVCKSTCCVPVPSCGASASSCQPSCCRTASCVSLL---CRP 233
Query: 818 IIPPGACCPLCAG 830
+ AC LC+G
Sbjct: 234 VCSRPACYSLCSG 246
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 47.8 bits (112), Expect = 5e-05
Identities = 39/129 (30%), Positives = 50/129 (38%), Gaps = 16/129 (12%)
Query: 491 THPCNPNPCPANELCE--VNRKGCPSGDPCLPYFCVQGCKLG--EASDFIVRQGTLIQVP 546
T+ CNP PC +C VN C C P F C++ E G
Sbjct: 752 TNDCNPLPCYNGGICVDGVNWFRCE----CAPGFAGPDCRINIDECQSSPCAYGA----- 802
Query: 547 SSAGEVGCYKICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCNVCSCFAG 606
+ E+ Y+ CSC C E+ I +SC G HG+S+ DCN C C G
Sbjct: 803 TCVDEINGYR-CSCPPGRAGPRCQEV--IGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDG 859
Query: 607 NLVCSTRLC 615
CS C
Sbjct: 860 RRDCSKVWC 868
Score = 39.7 bits (91), Expect = 0.014
Identities = 71/332 (21%), Positives = 98/332 (29%), Gaps = 63/332 (18%)
Query: 407 PEMWKAIACSLQIKPCHSKSRGSIICKS-----DCVEILKKCGDQNKFPEDHTAESICEL 461
PE W C L + C + + CK CV G + D A S C
Sbjct: 412 PEQWVGATCQLDVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHS 471
Query: 462 LSPTDDLKNCIPLDTYLRPSTLGNIVEEVTHPCNPNPCP--------------------A 501
+DL + + G + E C P+PC
Sbjct: 472 GGLCEDLAD--GFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFG 529
Query: 502 NELCEVNRKGCPSGDPCLPYFCVQGCKLG----EASDFIVRQGTLIQVPSSAGEVGCYKI 557
+ C V R+ CP G + C G AS G + P G C I
Sbjct: 530 GKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQP--GGNFSC--I 585
Query: 558 CSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSF-SIDCNVCSCFAG--NLVCSTRL 614
C G +G +C + C+ G ++ GT +D C C +G +C T
Sbjct: 586 CDSGFTG-------TYCHENIDDCL-GQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNP 637
Query: 615 --CLSE--HSSEDDRRTFTGLPCNCADQF-------------VPVCGQNGRTYPSACIAR 657
CL + HS C C D + C G Y S R
Sbjct: 638 NDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFR 697
Query: 658 CVGLQDHQFEFGSCMSKDPCNPNPCQKNQRCI 689
C + + C PNPC C+
Sbjct: 698 CACPPGWKGSTCAVAKNSSCLPNPCVNGGTCV 729
Score = 33.9 bits (76), Expect = 0.76
Identities = 65/291 (22%), Positives = 93/291 (31%), Gaps = 69/291 (23%)
Query: 428 GSIICKSDCVEILKKCGDQNKFPEDHTAESICELLSPTDDLKNCIPLDTYLRPSTLGNIV 487
G ++C D L CG + T ++ D C D Y G
Sbjct: 300 GGLLCDKD----LNYCGSHHPCTNGGTC------INAEPDQYRCTCPDGYS-----GRNC 344
Query: 488 EEVTHPCNPNPCPANELCEVNRKG----CPSG----------DPCLPYFCVQGCKLGEAS 533
E+ H C NPC C G CPSG D C C G
Sbjct: 345 EKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAG------- 397
Query: 534 DFIVRQGTLIQVPSSAGEVGCYKICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTS 593
GT + +V ++ C C + + C ++ D + C GG K
Sbjct: 398 ------GTCVD------QVDGFE-CICPEQWVGATC-QLDVNDCRGQCQHGGTCKDLVNG 443
Query: 594 FSIDC----NVCSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFV-PVCGQN-G 647
+ C C C++ C S ED G C+C F P+C +
Sbjct: 444 YQCVCPRGFGGRHCELERDECASSPCHSGGLCED---LADGFHCHCPQGFSGPLCEVDVD 500
Query: 648 RTYPSACI--ARCVGLQDHQF-----EFGS---CMSKDPCNPNPCQKNQRC 688
PS C ARC L+ + +FG + ++PC C+ C
Sbjct: 501 LCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGC 551
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 47.8 bits (112), Expect = 5e-05
Identities = 39/129 (30%), Positives = 50/129 (38%), Gaps = 16/129 (12%)
Query: 491 THPCNPNPCPANELCE--VNRKGCPSGDPCLPYFCVQGCKLG--EASDFIVRQGTLIQVP 546
T+ CNP PC +C VN C C P F C++ E G
Sbjct: 790 TNDCNPLPCYNGGICVDGVNWFRCE----CAPGFAGPDCRINIDECQSSPCAYGA----- 840
Query: 547 SSAGEVGCYKICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCNVCSCFAG 606
+ E+ Y+ CSC C E+ I +SC G HG+S+ DCN C C G
Sbjct: 841 TCVDEINGYR-CSCPPGRAGPRCQEV--IGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDG 897
Query: 607 NLVCSTRLC 615
CS C
Sbjct: 898 RRDCSKVWC 906
Score = 37.7 bits (86), Expect = 0.053
Identities = 70/329 (21%), Positives = 98/329 (29%), Gaps = 63/329 (19%)
Query: 410 WKAIACSLQIKPCHSKSRGSIICKS-----DCVEILKKCGDQNKFPEDHTAESICELLSP 464
WK I C + + C + + CK CV G + D A S C
Sbjct: 453 WKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGL 512
Query: 465 TDDLKNCIPLDTYLRPSTLGNIVEEVTHPCNPNPCP--------------------ANEL 504
+DL + + G + E C P+PC +
Sbjct: 513 CEDLAD--GFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKN 570
Query: 505 CEVNRKGCPSGDPCLPYFCVQGCKLG----EASDFIVRQGTLIQVPSSAGEVGCYKICSC 560
C V R+ CP G + C G AS G + P G C IC
Sbjct: 571 CSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQP--GGNFSC--ICDS 626
Query: 561 GQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSF-SIDCNVCSCFAG--NLVCSTRL--C 615
G +G +C + C+ G ++ GT +D C C +G +C T C
Sbjct: 627 GFTG-------TYCHENIDDCL-GQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDC 678
Query: 616 LSE--HSSEDDRRTFTGLPCNCADQF-------------VPVCGQNGRTYPSACIARCVG 660
L + HS C C D + C G Y S RC
Sbjct: 679 LPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCAC 738
Query: 661 LQDHQFEFGSCMSKDPCNPNPCQKNQRCI 689
+ + C PNPC C+
Sbjct: 739 PPGWKGSTCAVAKNSSCLPNPCVNGGTCV 767
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 46.6 bits (109), Expect = 1e-04
Identities = 117/565 (20%), Positives = 177/565 (31%), Gaps = 155/565 (27%)
Query: 98 GWVGLGCCELAIALECRQACKQASSKNDISK----VCRKEY-----ENALFSCISRNEMG 148
GW+G C ++ I +C C+ +S D+ +C Y E + C S
Sbjct: 441 GWMGQNC-DININ-DCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNP--- 495
Query: 149 SVCCSYAGHHTNCREYCQAIFRTDSSPGPSQIKAVENYCASISPQLIHCVNNYTQSYPMR 208
C GH N Q + T S Q+ + +C N Q+
Sbjct: 496 ---CLNGGHCQNEINRFQCLCPTGFSGNLCQL------------DIDYCEPNPCQNGAQC 540
Query: 209 NPTDSLYCCDRAEDHACQNACKRILMSKKTEMEIVDGLIEGCKTQPLPQDPLWQCFLESS 268
S Y C ED+ +N + T E++D + P E
Sbjct: 541 YNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTP---------EGV 591
Query: 269 QSVHPGVTVHPPPSTGLDGAKLHC-CSKANTST-CRELCTKLYSMSWGN----------- 315
+ + V G K C C+K T T C E S N
Sbjct: 592 RYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSY 651
Query: 316 ----TQSWQEFDRFCEYNPVEVSMLTCLADVREPCQLG--CRNLT---YCTNFNNRPTEL 366
+ W+ +CE N + S + PC G CR+L YC N +
Sbjct: 652 KCICSDGWE--GAYCETNINDCS--------QNPCHNGGTCRDLVNDFYCDCKNGWKGKT 701
Query: 367 FRSCNAQSDQGAMNDM-KLWEKGSIKMPFINIPVLDIKKCQ-PEMWKAIACSLQIK---- 420
S ++Q D+ N+ +++G D KC P W+ C++
Sbjct: 702 CHSRDSQCDEATCNNGGTCYDEG------------DAFKCMCPGGWEGTTCNIARNSSCL 749
Query: 421 --PCHSKSRGSIICKSDCVEILKKCGDQNKFPEDHTAESICELLSPTDDLKNCIPLDTYL 478
PCH+ G+ + + + K G +
Sbjct: 750 PNPCHNG--GTCVVNGESFTCVCKEGWE-------------------------------- 775
Query: 479 RPSTLGNIVEEVTHPCNPNPCPANELCEVNRKGCPSGD-----PCLPYFCVQGCKLG--E 531
G I + T+ C+P+PC N C GD C P F C++ E
Sbjct: 776 -----GPICAQNTNDCSPHPC-------YNSGTCVDGDNWYRCECAPGFAGPDCRININE 823
Query: 532 ASDFIVRQGTLIQVPSSAGEVGCYK-ICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSH 590
G + E+ Y+ +C G SG C E+ + CI G
Sbjct: 824 CQSSPCAFGA-----TCVDEINGYRCVCPPGHSGA--KCQEVS----GRPCITMGSVIPD 872
Query: 591 GTSFSIDCNVCSCFAGNLVCSTRLC 615
G + DCN C C G + CS C
Sbjct: 873 GAKWDDDCNTCQCLNGRIACSKVWC 897
>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
sapiens]
Length = 2134
Score = 45.8 bits (107), Expect = 2e-04
Identities = 157/773 (20%), Positives = 266/773 (34%), Gaps = 171/773 (22%)
Query: 86 NSSLPGVFKKSDGWV------GLGCCELAIALECRQACKQASSKNDISKVCRKEY---EN 136
NS +PG + G G+ C I + K A+ ND +C EY +
Sbjct: 664 NSKIPGDCPNAVGKSYEVCEDGIQHCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRD 723
Query: 137 ALFSCISRNEMGSVCCSYA-GHHTNCREYCQAIFRTDSSP--------GPSQIKAVENYC 187
+C + +E+ +C S G + R + T P GPS C
Sbjct: 724 KTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPAT----C 779
Query: 188 ASISP-QLIHCVNNYT--QSYPMRNPTDSLYCCDRAEDHACQNACKRILMSKKTEMEIVD 244
++++P Q CV+ T + Y + + + C +AE C+++ + E+ +
Sbjct: 780 SNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAEC-PCESSG-----TVYQPGEVRE 833
Query: 245 GLIEGCKTQPLPQDPLWQCFLESSQSVHPG-VTVHPPPSTGLDGAKLHCCSKANTSTCRE 303
G C +Q QD W C ++++ PG V T DG K + C
Sbjct: 834 G---PCGSQCTCQDAKWSC----TEALCPGRCKVEGSSLTTFDGVKYNF-----PGNCHF 881
Query: 304 LCTKLYSMSWGNTQSWQEFDRFCEYNPVEVSMLTCLADVREPCQLGCRNLTYCTNFNNRP 363
L + + W + V + C + C ++T N ++ P
Sbjct: 882 LAV--------HNEDWS----------ISVELRPCPSGQTGTC---LNSVTLLLN-SSVP 919
Query: 364 TELFRSCNAQSDQGAMNDMKLWEKGSIKMPFINIPVLDIKKCQPEMWKAIACSLQIKPCH 423
+ + + G + + K+ +G I I Q E + + +QI P
Sbjct: 920 VDKY----VFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVM 975
Query: 424 SKSRGSIICKSDCVEILKKCGDQNKFPEDH--TAESICELLS------------PTDDLK 469
+ + + + CG N ED ++++I E S P +
Sbjct: 976 QLYVS--MPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKGNPS 1033
Query: 470 NCIPLDTYLRPSTLGNIVEEVTHP---CNP--NPCPANELCEVNRKGCPSGDPCLPYFC- 523
+CI ++ I+ + + P C+P NP P +E C+ C + CL
Sbjct: 1034 SCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILG 1093
Query: 524 --VQGCKLGEASDFIVRQGT-LIQVPSSAGEVGCYKICSCGQSGL--------------- 565
V+ C E +IV T L + +G V Y + +C S
Sbjct: 1094 NYVKAC--AEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVP 1151
Query: 566 LENCM---------EMHCI-DLQKSCIVGGKRKSHGTSFSIDCNVCSCFAGNLVCSTRLC 615
++ C E +C+ Q C + + G ID N C C G L+C +
Sbjct: 1152 VDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPID 1211
Query: 616 L--------SEHSSEDDRRTFTGLPCNCADQFVPVCGQN-----GRTYPSACIARCVGLQ 662
L +E+ D + C+ + +PV +N G P + G+
Sbjct: 1212 LTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGI- 1270
Query: 663 DHQFEFGSCMSKDPCNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLACDQVQDP 722
C+ + C PC R + V GC++ C+ +C Q +
Sbjct: 1271 --------CVFPNDC---PCSFGGREYDEGSV-----TSVGCNECTCIKGSWSCTQNE-- 1312
Query: 723 VCDTDHMEHNNLCTLYQR-------GKSLSYKGPCQPFCRATEPVCGHNGETY 768
C T +C +Y GKS S+ G CQ E CGH T+
Sbjct: 1313 -CQT-------ICHIYGEGHVRTFDGKSYSFDGLCQ--YSFLEDYCGHENGTF 1355
Score = 30.4 bits (67), Expect = 8.4
Identities = 53/252 (21%), Positives = 84/252 (33%), Gaps = 55/252 (21%)
Query: 560 CGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCNVCSCFAG---------NLVC 610
CG+ L N +M CID + C K + T + S G ++VC
Sbjct: 700 CGKVAALSNDYKMICID--EYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVC 757
Query: 611 STRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCV----GLQDHQF 666
T+ C +H ++ C C S C++ C L D
Sbjct: 758 ETQRCPEQHIYKE-----------CGPSNPATCSNVAPFQDSECVSGCTCPEGYLLDDIG 806
Query: 667 EFGSCMSKDPCNPNPCQKNQRCIPKPQV--------CLTTFDKFGCSQYECVPRQLACDQ 718
E G C+ K C PC+ + +V C K+ C++ C R C
Sbjct: 807 EKGKCVLKAEC---PCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGR---CKV 860
Query: 719 VQDPVCDTDHMEHN-----NLCTLYQRGKSLSYK-GPCQPFCRATEPVCGHNGETYSSVC 772
+ D +++N + ++ S+S + PC G G +SV
Sbjct: 861 EGSSLTTFDGVKYNFPGNCHFLAVHNEDWSISVELRPCP---------SGQTGTCLNSVT 911
Query: 773 AAYSDRVAVDYY 784
+ V VD Y
Sbjct: 912 LLLNSSVPVDKY 923
>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
sapiens]
Length = 2134
Score = 45.1 bits (105), Expect = 3e-04
Identities = 157/773 (20%), Positives = 266/773 (34%), Gaps = 171/773 (22%)
Query: 86 NSSLPGVFKKSDGWV------GLGCCELAIALECRQACKQASSKNDISKVCRKEY---EN 136
NS +PG + G G+ C I + K A+ ND +C EY +
Sbjct: 664 NSKIPGDCPNAVGKSYEVCEDGIQHCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRD 723
Query: 137 ALFSCISRNEMGSVCCSYA-GHHTNCREYCQAIFRTDSSP--------GPSQIKAVENYC 187
+C + +E+ +C S G + R + T P GPS C
Sbjct: 724 KTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPAT----C 779
Query: 188 ASISP-QLIHCVNNYT--QSYPMRNPTDSLYCCDRAEDHACQNACKRILMSKKTEMEIVD 244
++++P Q CV+ T + Y + + + C +AE C+++ + E+ +
Sbjct: 780 SNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAEC-PCESSG-----TVYQPGEVRE 833
Query: 245 GLIEGCKTQPLPQDPLWQCFLESSQSVHPG-VTVHPPPSTGLDGAKLHCCSKANTSTCRE 303
G C +Q QD W C ++++ PG V T DG K + C
Sbjct: 834 G---PCGSQCTCQDAKWSC----TEALCPGRCKVEGSSLTTFDGVKYNF-----PGNCHF 881
Query: 304 LCTKLYSMSWGNTQSWQEFDRFCEYNPVEVSMLTCLADVREPCQLGCRNLTYCTNFNNRP 363
L + + W + V + C + C ++T N ++ P
Sbjct: 882 LAV--------HNEDWS----------ISVELRPCPSGQTGTC---LNSVTLLLN-SSVP 919
Query: 364 TELFRSCNAQSDQGAMNDMKLWEKGSIKMPFINIPVLDIKKCQPEMWKAIACSLQIKPCH 423
+ + + G + + K+ +G I I Q E + + +QI P
Sbjct: 920 VDKY----VFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVM 975
Query: 424 SKSRGSIICKSDCVEILKKCGDQNKFPEDH--TAESICELLS------------PTDDLK 469
+ + + + CG N ED ++++I E S P +
Sbjct: 976 QLYVS--MPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKGNPS 1033
Query: 470 NCIPLDTYLRPSTLGNIVEEVTHP---CNP--NPCPANELCEVNRKGCPSGDPCLPYFC- 523
+CI ++ I+ + + P C+P NP P +E C+ C + CL
Sbjct: 1034 SCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILG 1093
Query: 524 --VQGCKLGEASDFIVRQGT-LIQVPSSAGEVGCYKICSCGQSGL--------------- 565
V+ C E +IV T L + +G V Y + +C S
Sbjct: 1094 NYVKAC--AEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVP 1151
Query: 566 LENCM---------EMHCI-DLQKSCIVGGKRKSHGTSFSIDCNVCSCFAGNLVCSTRLC 615
++ C E +C+ Q C + + G ID N C C G L+C +
Sbjct: 1152 VDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPID 1211
Query: 616 L--------SEHSSEDDRRTFTGLPCNCADQFVPVCGQN-----GRTYPSACIARCVGLQ 662
L +E+ D + C+ + +PV +N G P + G+
Sbjct: 1212 LTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGI- 1270
Query: 663 DHQFEFGSCMSKDPCNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLACDQVQDP 722
C+ + C PC R + V GC++ C+ +C Q +
Sbjct: 1271 --------CVFPNDC---PCSFGGREYDEGSV-----TSVGCNECTCIKGSWSCTQNE-- 1312
Query: 723 VCDTDHMEHNNLCTLYQR-------GKSLSYKGPCQPFCRATEPVCGHNGETY 768
C T +C +Y GKS S+ G CQ E CGH T+
Sbjct: 1313 -CQT-------ICHIYGEGHVRTFDGKSYSFDGLCQ--YSFLEDYCGHENGTF 1355
Score = 30.4 bits (67), Expect = 8.4
Identities = 53/252 (21%), Positives = 84/252 (33%), Gaps = 55/252 (21%)
Query: 560 CGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCNVCSCFAG---------NLVC 610
CG+ L N +M CID + C K + T + S G ++VC
Sbjct: 700 CGKVAALSNDYKMICID--EYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVC 757
Query: 611 STRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCV----GLQDHQF 666
T+ C +H ++ C C S C++ C L D
Sbjct: 758 GTQRCPEQHIYKE-----------CGPSNPATCSNVAPFQDSECVSGCTCPEGYLLDDIG 806
Query: 667 EFGSCMSKDPCNPNPCQKNQRCIPKPQV--------CLTTFDKFGCSQYECVPRQLACDQ 718
E G C+ K C PC+ + +V C K+ C++ C R C
Sbjct: 807 EKGKCVLKAEC---PCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGR---CKV 860
Query: 719 VQDPVCDTDHMEHN-----NLCTLYQRGKSLSYK-GPCQPFCRATEPVCGHNGETYSSVC 772
+ D +++N + ++ S+S + PC G G +SV
Sbjct: 861 EGSSLTTFDGVKYNFPGNCHFLAVHNEDWSISVELRPCP---------SGQTGTCLNSVT 911
Query: 773 AAYSDRVAVDYY 784
+ V VD Y
Sbjct: 912 LLLNSSVPVDKY 923
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 44.7 bits (104), Expect = 4e-04
Identities = 76/319 (23%), Positives = 110/319 (34%), Gaps = 47/319 (14%)
Query: 431 ICKSDCVEILKKCGDQNKFPEDHTAESICELLSPTD--DLKNCIPLDTYLRPSTLGNIVE 488
+C ++C + ++ E T E EL+ P D D CI Y G E
Sbjct: 283 LCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTG---E 339
Query: 489 EVTHPCNPNPCPANELCEVNRKGCP---SGDPCLPYFCVQGC-KLGEASDFIVRQGTLIQ 544
+ P P+ C CE + C +G C C C G D
Sbjct: 340 DCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGF- 398
Query: 545 VPSSAGEVGCYKICS-----------CGQSGLLENCMEMHCID--LQKSCIVGGKRKSHG 591
+ GE+ C CS C + E+C ++ C + + V GK
Sbjct: 399 TGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQ 458
Query: 592 TSFSIDCNVCSC-----FAGNLVCSTRLCLSEHSSED--DRR-----TFTGL----PCNC 635
DC+ SC G V +C ++ ED DR+ + GL C C
Sbjct: 459 GFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVC 518
Query: 636 ADQFV-PVCGQNGRTYPSACIA--RCVGLQD--HQFEFGSCMSKDPCNPNPCQKNQRCIP 690
D F P C + + P+ C RCV Q H+ G + C P+ C RC+
Sbjct: 519 EDGFTGPDCAE--LSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRC-PSDCHGQGRCVD 575
Query: 691 KPQVCLTTFDKFGCSQYEC 709
+C F C Q+ C
Sbjct: 576 GQCICHEGFTGLDCGQHSC 594
>gi|61743978 stabilin 1 precursor [Homo sapiens]
Length = 2570
Score = 43.9 bits (102), Expect = 7e-04
Identities = 48/201 (23%), Positives = 73/201 (36%), Gaps = 29/201 (14%)
Query: 594 FSIDC-NVCSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPS 652
F DC +VCSC G +C + F G DQ +PVC + +
Sbjct: 156 FGPDCQSVCSCVHG-------VCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNT 208
Query: 653 ACIAR---CVGLQDHQFEFGSCMSKDPCNPNPCQKNQRC--IPKPQVCLTTFDKFGCSQY 707
C A C L + + C + +PC P+PC +C PK Q + +
Sbjct: 209 QCSAEAPSCRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHGDGM 268
Query: 708 ECVPRQLACDQVQDPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGHNGET 767
C+P+ D + C + ++ LC Y+ P Q FC + N
Sbjct: 269 VCLPKDPCTDNLGG--CPS----NSTLCV---------YQKPGQAFCTCRPGLVSINSNA 313
Query: 768 YSSVCAAYSDRVAVDYYGDCQ 788
S+ C A+ + D CQ
Sbjct: 314 -SAGCFAFCSPFSCDRSATCQ 333
>gi|38490571 keratin associated protein 10-7 [Homo sapiens]
Length = 370
Score = 43.9 bits (102), Expect = 7e-04
Identities = 83/338 (24%), Positives = 112/338 (33%), Gaps = 80/338 (23%)
Query: 512 CPSGDPCLPYFCVQGCKLGEASDFIVRQGTLIQVPSSAGEVGCYKICS---CGQSGL-LE 567
C + PCL C ++ + S + GC C+ C QS L
Sbjct: 46 CCAPAPCLSLVCTP-------VSYVSSPCCRVTCEPSPCQSGCTSSCTPSCCQQSSCQLA 98
Query: 568 NCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCNVCSCFAGNLVCSTRLCLSEHSSEDDRRT 627
C C Q++C V K+ + C C VCS + SS
Sbjct: 99 CCASSPC---QQACCVPVCCKT------VCCKPVYCVP---VCSGDSSCCQQSSCQSA-C 145
Query: 628 FTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFGSCMS-------KDPCNPN 680
T PC A VP+C C C G+ + SC+S + C P+
Sbjct: 146 CTSSPCQQAC-CVPIC----------CKPVCSGISSSCCQQSSCVSCVSSPCCQAVCEPS 194
Query: 681 PCQKN--QRCIP--------KPQVCLTTFDKFGCSQYECVPRQLACDQVQD-PVCDTDHM 729
PCQ C P KP C ++ C Q CVP + C V P C D
Sbjct: 195 PCQSGCISSCTPSCCQQSSCKPACCTSS----PCQQACCVP--VCCKPVCCVPTCSDDS- 247
Query: 730 EHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGHNGETYSSVCAAYSDRVAVDYYGDCQA 789
+ C S S +G C P C +PVC VC+ S CQ
Sbjct: 248 --GSCCQPACCTSSQSQQGCCVPVC--CKPVC------CVPVCSGASTSC-------CQQ 290
Query: 790 VGVLSEHSSVAECASVKCPSLLAAGCKPIIPPGACCPL 827
+ + C SLL C+P+ P C P+
Sbjct: 291 SSCQPACCTTSCCRPSSSVSLL---CRPVCRPACCVPV 325
Score = 42.7 bits (99), Expect = 0.002
Identities = 60/235 (25%), Positives = 81/235 (34%), Gaps = 33/235 (14%)
Query: 608 LVCSTRLCLSEHSSEDDRRTFTGLPCNCADQF-VPVCGQNGRTYPSACIARCVGLQDHQF 666
+ ST S S R G +C+D + V C ++ P A C+ L
Sbjct: 1 MAASTMSVCSSDLSYGSRVCLPGSCDSCSDSWQVDDCPESCCEPPCCAPAPCLSLVCTPV 60
Query: 667 EF-GSCMSKDPCNPNPCQKNQRCIPKPQVC------LTTFDKFGCSQYECVP---RQLAC 716
+ S + C P+PCQ P C L C Q CVP + + C
Sbjct: 61 SYVSSPCCRVTCEPSPCQSGCTSSCTPSCCQQSSCQLACCASSPCQQACCVPVCCKTVCC 120
Query: 717 DQVQ-DPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFC---RATEPVCGHNGETYSSVC 772
V PVC D ++ C + PCQ C +PVC SS C
Sbjct: 121 KPVYCVPVCSGD----SSCCQQSSCQSACCTSSPCQQACCVPICCKPVC----SGISSSC 172
Query: 773 AAYSDRVAVDYYGDCQAVGVLS--EHSSVAECASVKCPSLLAAGCKPIIPPGACC 825
S V+ CQAV S + ++ C C + CKP ACC
Sbjct: 173 CQQSSCVSCVSSPCCQAVCEPSPCQSGCISSCTPSCCQQ---SSCKP-----ACC 219
>gi|238859649 keratin associated protein 10-8 [Homo sapiens]
Length = 259
Score = 43.5 bits (101), Expect = 0.001
Identities = 50/202 (24%), Positives = 70/202 (34%), Gaps = 39/202 (19%)
Query: 596 IDCNVCSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACI 655
+ C C +G T C + S + T PC A VPVC ++ P C+
Sbjct: 79 VSCEPSPCQSGCTDSCTPSCCQQSSCQP--ACCTSSPCQQAC-CVPVCCKSNCCKPVCCV 135
Query: 656 ARCVGLQDHQFEFGSCMSKDPCNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVP---- 711
+ C G + SC S C +PCQ+ C+P +C C CVP
Sbjct: 136 SICSGASSPCCQQSSCQSA-CCTFSPCQQ-ACCVP---IC--------CKPICCVPVCSG 182
Query: 712 -RQLACDQVQ-DPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFC-----------RATE 758
L C + P C T C SL + C+P C + +
Sbjct: 183 ASSLCCQKSSCQPACCT------TSCCRPSSSVSLLCRPVCRPACCVPVPSCCVPASSCQ 236
Query: 759 PVCGHNGETYSSVCAAYSDRVA 780
P C H S +C R+A
Sbjct: 237 PSCCHPASCLSFLCRPACSRLA 258
Score = 33.5 bits (75), Expect = 0.99
Identities = 55/244 (22%), Positives = 81/244 (33%), Gaps = 51/244 (20%)
Query: 599 NVCSCFAGNL--VCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIA 656
+VCS G++ V S C D+ + P +CA C P+ C+A
Sbjct: 18 SVCSSDVGHVSRVSSPSTCTGSSWQVDNCQESCCEPRSCASS----CCTPSCCAPAPCLA 73
Query: 657 R-CVGLQDHQFEFGSCMS--KDPCNPNPCQKNQR----CIPKP---QVCLTTFDKFGCSQ 706
C + E C S D C P+ CQ++ C P C+ K C +
Sbjct: 74 LVCAPVS---CEPSPCQSGCTDSCTPSCCQQSSCQPACCTSSPCQQACCVPVCCKSNCCK 130
Query: 707 YECVPRQLACDQVQDPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGHNGE 766
C C P C + + CT ++ C+P C PVC
Sbjct: 131 PVCCVS--ICSGASSPCCQQSSCQ-SACCTFSPCQQACCVPICCKPICCV--PVCSGA-- 183
Query: 767 TYSSVCAAYSDRVAVDYYGDCQAVGVLSEHSSVAECASVKC---PSLLAAGCKPIIPPGA 823
SS+C S CQ C + C S ++ C+P+ P
Sbjct: 184 --SSLCCQKSS---------CQPA-----------CCTTSCCRPSSSVSLLCRPVCRPAC 221
Query: 824 CCPL 827
C P+
Sbjct: 222 CVPV 225
>gi|108773804 Fraser syndrome 1 [Homo sapiens]
Length = 4011
Score = 43.1 bits (100), Expect = 0.001
Identities = 66/287 (22%), Positives = 97/287 (33%), Gaps = 76/287 (26%)
Query: 580 SCIVGGKRKSHGTSF-SIDCNVCSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQ 638
SC K HGT + S C+VCSC G + C+ + C P +C Q
Sbjct: 94 SCHHEKKIHEHGTEWASSPCSVCSCNHGEVRCTPQPC---------------PPLSCGHQ 138
Query: 639 ---FVPVCGQNGRTYPSACIARCVGL------QDHQFEFG---------SCMSKD----- 675
F+P +C CVGL + H F+ G C+ ++
Sbjct: 139 ELAFIP---------EGSCCPVCVGLGKPCSYEGHVFQDGEDWRLSRCAKCLCRNGVAQC 189
Query: 676 ---PCNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECV---PRQLACDQVQDPVCDTDHM 729
C P C +++ + P C CS V Q + + +CD +
Sbjct: 190 FTAQCQPLFCNQDETVVRVPGKCCPQCSARSCSAAGQVYEHGEQWSENACTTCICDRGEV 249
Query: 730 E-HNNLCTLYQRGKSLS---YKGPCQPFCRATEPVCGHNGETYSSVCAAYSDRVAVDYYG 785
H C + GK S G C C + C ++G Y D + +
Sbjct: 250 RCHKQACLPLRCGKGQSRARRHGQCCEECVSPAGSCSYDG------VVRYQD----EMWK 299
Query: 786 DCQAVGVLSEHSSV----AECASVKCPSLLAAGCKPIIPPGACCPLC 828
+ +H V ECA V+C A + I G CCP C
Sbjct: 300 GSACEFCMCDHGQVTCQTGECAKVEC----ARDEELIHLDGKCCPEC 342
Score = 35.4 bits (80), Expect = 0.26
Identities = 41/237 (17%), Positives = 70/237 (29%), Gaps = 70/237 (29%)
Query: 598 CNVCSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIAR 657
C C C ++C +C + + + C + C+ R
Sbjct: 46 CQSCRCHGDIVICKPAVCRNPQCAFEKGEVLQIAANQCCPE---------------CVLR 90
Query: 658 CVGLQDHQ---FEFGSCMSKDPCNPNPCQKNQ-RCIPKPQVCLTTFDKFGCSQYECVPRQ 713
G H+ E G+ + PC+ C + RC P+P C C ++
Sbjct: 91 TPGSCHHEKKIHEHGTEWASSPCSVCSCNHGEVRCTPQP-----------CPPLSCGHQE 139
Query: 714 LACDQVQDPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGHNGETYSSVCA 773
LA +G C P C C + G +
Sbjct: 140 LA----------------------------FIPEGSCCPVCVGLGKPCSYEGHVFQD--- 168
Query: 774 AYSDRVAVDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGCKPIIP-PGACCPLCA 829
+ + C + VA+C + +C L + ++ PG CCP C+
Sbjct: 169 --GEDWRLSRCAKCLC------RNGVAQCFTAQCQPLFCNQDETVVRVPGKCCPQCS 217
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 42.7 bits (99), Expect = 0.002
Identities = 119/550 (21%), Positives = 173/550 (31%), Gaps = 111/550 (20%)
Query: 287 GAKLHCCSKANTSTCREL---CTKLYSMSWGNTQSWQEFDRFCEYNPVEVSMLTCLADVR 343
G K +C +TC + C + G + ++++ F P TC D+
Sbjct: 812 GYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDIN 871
Query: 344 EPCQLGCRNLTYCTNFNNRPTELFRSCNAQSDQGAMNDMKLWEKGSIKMPFINIPVLDIK 403
E CR+ C N T C+ Q+ N DI
Sbjct: 872 ECVLSPCRHGASCQN-----THGGYRCHCQAGYSGRNCET-----------------DID 909
Query: 404 KCQPEMWKAIACSLQIKPCH---SKSRGSIICKSDCVEILKKCGDQNKFPEDHTAESICE 460
C+P PCH S + G DC+ G + F E+ E +
Sbjct: 910 DCRPN------------PCHNGGSCTDGINTAFCDCLP-----GFRGTFCEEDINECASD 952
Query: 461 LLSPTDDLKNCIPLDTYLRPSTLGNI-VEEVTHPCNPNPCPANELCE--VNRKGCPSGDP 517
+ +C+ T P+ I E T C + C C +N C
Sbjct: 953 PCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCL---- 1008
Query: 518 CLPYFCVQGCK--LGEASDFIVRQGTLIQVPSSAGEVGCYKICSCGQSGLLENCMEM-HC 574
C P F C+ + E G Q G Y+ C+C Q NC + H
Sbjct: 1009 CPPGFTGSYCQHDVNECDSQPCLHGGTCQ-----DGCGSYR-CTCPQGYTGPNCQNLVHW 1062
Query: 575 IDLQKSCIVGGKRKSHGTSFSIDC----NVCSCFAGNLVCST----------RLCLSEHS 620
D C GGK T + +C C ++ C RLC
Sbjct: 1063 CD-SSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGL 1121
Query: 621 SEDDRRT--------FTGLPC-NCADQFVPVCGQNGRT-------YPSACIARCVGLQDH 664
D T +TG C + D+ P QNG T Y C+A G+
Sbjct: 1122 CVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGV--- 1178
Query: 665 QFEFGSCMSK-DPCNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLACDQVQDPV 723
+C + D C +PCQ C+ P + + G C C+ DPV
Sbjct: 1179 -----NCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPR-GTQGVHCEINVDDCNPPVDPV 1232
Query: 724 CDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGHNGETYSSVCAAYSDRVAV-- 781
+ +N C G Y C P E G E S+ C A + V
Sbjct: 1233 SRSPKCFNNGTCVDQVGG----YSCTCPPGF-VGERCEGDVNECLSNPCDARGTQNCVQR 1287
Query: 782 --DYYGDCQA 789
D++ +C+A
Sbjct: 1288 VNDFHCECRA 1297
Score = 35.4 bits (80), Expect = 0.26
Identities = 81/345 (23%), Positives = 111/345 (32%), Gaps = 96/345 (27%)
Query: 493 PCNPNPCPANELCEVNRKGCPSGD-----PCLPYFCVQGCK--LGEASDFIVRQGTLIQV 545
PC+P+PC C P+GD CLP F Q C+ + + + G
Sbjct: 221 PCSPSPCQNGGTCR------PTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNG----- 269
Query: 546 PSSAGEVGCYKICSCGQSGLLENCME--MHCIDLQKSCIVGGKRKSHGTSFSIDCNVC-- 601
+ V Y C C + C E C + +C GG H T +C VC
Sbjct: 270 GACVDGVNTYN-CRCPPEWTGQYCTEDVDECQLMPNACQNGG--TCHNTHGGYNC-VCVN 325
Query: 602 -----SCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIA 656
C C++ C + D +F C C +GRT
Sbjct: 326 GWTGEDCSENIDDCASAACFHGATCHDRVASFY---CEC---------PHGRT------- 366
Query: 657 RCVGLQDHQFEFGSCMSKDPCNPNPCQKNQRCIPKPQ------VCLTTFDKFGCSQYECV 710
GL C D C NPC + C P C + + CSQ
Sbjct: 367 ---GL--------LCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQ---- 411
Query: 711 PRQLACDQVQDPVCDTDHMEHNNLCTLYQRGKSLSYKG--PCQPFCRATEPVCGHN-GET 767
V + + EH GK ++ G CQ T P C + E
Sbjct: 412 -------DVDECSLGANPCEH--------AGKCINTLGSFECQCLQGYTGPRCEIDVNEC 456
Query: 768 YSSVCAAYSDRVAVDYYGDCQAV---GVLSEHSSV--AECASVKC 807
S+ C +D +D G+ Q + G H V ECAS C
Sbjct: 457 VSNPC--QNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPC 499
Score = 34.7 bits (78), Expect = 0.45
Identities = 33/136 (24%), Positives = 47/136 (34%), Gaps = 21/136 (15%)
Query: 574 CIDLQKSCIVGGKRKSHGTSFSIDCNVCSCFAGNLVCSTRLCLSEHSSED------DRRT 627
C ++C+ GGK ++ + + C F G CLS DRR
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCG--GAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRG 81
Query: 628 FTGLPCNCADQFV-PVC------------GQNGRTYPSACIARCVGLQDHQFEFGSCMSK 674
C+CA F P+C +NG T + + SC
Sbjct: 82 VADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQA 141
Query: 675 DPCNPNPCQKNQRCIP 690
DPC NPC +C+P
Sbjct: 142 DPCASNPCANGGQCLP 157
Score = 33.9 bits (76), Expect = 0.76
Identities = 53/258 (20%), Positives = 85/258 (32%), Gaps = 53/258 (20%)
Query: 479 RPSTLGNIVEEVTHPCNPNPC--------------------PANELCEVNRKGCPSGDPC 518
RP G+ E + C+ PC CE+N C S PC
Sbjct: 592 RPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCAS-SPC 650
Query: 519 LPYFCVQGCKLGEASDFIVRQGTL--IQVPSSAGEVGCYK--ICSCGQSGLLENCMEMH- 573
C+ E + G++ I + AG C+ C G +G C E +
Sbjct: 651 DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGN-PCHNGGTCEDGINGFTCRCPEGYH 709
Query: 574 ---CIDLQKSC----IVGGKRKSHGTSFSIDCNV----CSCFAGNLVCSTRLCLSEHSSE 622
C+ C V G + + DC+ +C N C + C++ + +
Sbjct: 710 DPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCK 769
Query: 623 DDRRTFTGLPCNCADQF--------VPVCGQNGRTYPSACIARCVGLQDH---QFEFGSC 671
D +G C C + F + C N CI G + + + +C
Sbjct: 770 D---MTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATC 826
Query: 672 -MSKDPCNPNPCQKNQRC 688
+ PC P+PC+ C
Sbjct: 827 EVVLAPCAPSPCRNGGEC 844
Score = 32.3 bits (72), Expect = 2.2
Identities = 64/289 (22%), Positives = 92/289 (31%), Gaps = 63/289 (21%)
Query: 489 EVTHPCNPNPCPANELCEVNRKGCPSGDPCLPYFCVQG-------CKLGEASDFIVRQGT 541
+VTH C P + CE N CP + CV G C +
Sbjct: 238 DVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVD 297
Query: 542 LIQVPSSAGEVG--CYKI-----CSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSF 594
Q+ +A + G C+ C C E+C E +C G SF
Sbjct: 298 ECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASF 357
Query: 595 SIDCN------VCSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFV-PVC---- 643
+C +C N C + C +E S+ D C C + P C
Sbjct: 358 YCECPHGRTGLLCHL---NDACISNPC-NEGSNCDTNPVNGKAICTCPSGYTGPACSQDV 413
Query: 644 -----GQNGRTYPSACI-----ARCVGLQDH-----QFEFGSCMSKDPCNPNPCQKNQRC 688
G N + CI C LQ + + + C+S NPCQ + C
Sbjct: 414 DECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVS------NPCQNDATC 467
Query: 689 IPKPQVCLTTFDKFGCSQYECVP--RQLACDQVQDPVCDTDHMEHNNLC 735
+ D+ G Q C+P + C +V C + HN C
Sbjct: 468 L----------DQIGEFQCICMPGYEGVHC-EVNTDECASSPCLHNGRC 505
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 42.4 bits (98), Expect = 0.002
Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 1/73 (1%)
Query: 544 QVPSSAGEVGCYKICSCGQSGLLENCMEMHCIDLQK-SCIVGGKRKSHGTSFSIDCNVCS 602
Q S A E C C C + +L++ + C+ + K +C+ G + G ++S DC C+
Sbjct: 358 QEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCT 417
Query: 603 CFAGNLVCSTRLC 615
C G C C
Sbjct: 418 CSGGRWSCQEVPC 430
Score = 38.1 bits (87), Expect = 0.040
Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 4/65 (6%)
Query: 553 GCYKICSCGQS-GLLENCMEMHCIDL-QKSCIVGGKRKSHGTSFSIDCNVCSCFAGNLVC 610
GC+ C G+S +L++ C+ L Q C GG+ S GTSF+ C+ C+C G C
Sbjct: 1018 GCF--CPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTCSGGLWQC 1075
Query: 611 STRLC 615
C
Sbjct: 1076 QDLPC 1080
Score = 33.1 bits (74), Expect = 1.3
Identities = 23/89 (25%), Positives = 31/89 (34%), Gaps = 21/89 (23%)
Query: 547 SSAGEVGCYKICSCGQSGLLENCMEMHCI-------------------DLQKSCIVGGKR 587
SSAG G + SC + C HC+ + C+
Sbjct: 1465 SSAGTPGAECLRSCHTLDV--GCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEAT 1522
Query: 588 KSHGTSFSIDCNVCSCFAGNLVCSTRLCL 616
G + +DCN C+C CS RLCL
Sbjct: 1523 YKPGETIRVDCNTCTCRNRRWECSHRLCL 1551
>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
Length = 2013
Score = 42.4 bits (98), Expect = 0.002
Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 1/73 (1%)
Query: 544 QVPSSAGEVGCYKICSCGQSGLLENCMEMHCIDLQK-SCIVGGKRKSHGTSFSIDCNVCS 602
Q S A E C C C + +L++ + C+ + K +C+ G + G ++S DC C+
Sbjct: 358 QEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCT 417
Query: 603 CFAGNLVCSTRLC 615
C G C C
Sbjct: 418 CSGGRWSCQEVPC 430
>gi|63053517 keratin associated protein 10-5 [Homo sapiens]
Length = 271
Score = 42.4 bits (98), Expect = 0.002
Identities = 58/236 (24%), Positives = 73/236 (30%), Gaps = 47/236 (19%)
Query: 610 CSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFG 669
C T CL T P +C P C PS C + C
Sbjct: 31 CGTAPCL----------TLVCTPVSCVSS--PCC--QAACEPSPCQSGCTSSCTP----- 71
Query: 670 SCMSKDPCNPNPCQKNQRCIP---KPQVCLTTFDKFG---CSQYECVPRQLACDQVQD-- 721
SC C +PCQ+ C+P KP CL T K C Q C P A Q
Sbjct: 72 SCCQPACCASSPCQQ-ACCVPVCCKPVCCLPTCSKDSSSCCQQSSCQPTCCASSSCQQSC 130
Query: 722 --PVCDTDHMEHNNLC---TLYQRGKSLSYKGPCQPFCRATEPVCGHNGETYSSVCAAYS 776
PVC +C T + S CQP C + P Y VC
Sbjct: 131 CVPVCCKP------VCCVPTCSEDSSSCCQHSSCQPTCCTSSPC---QQSCYVPVCCKPV 181
Query: 777 DRVAVDYYGDCQAVGV--LSEHSSVAECASVKC---PSLLAAGCKPIIPPGACCPL 827
+ C + S C + C S ++ C+PI P C P+
Sbjct: 182 CFKPICCVPVCSGASTSCCQQSSCQPACCTTSCCRPSSSVSLLCRPICRPACCVPI 237
Score = 37.4 bits (85), Expect = 0.069
Identities = 56/227 (24%), Positives = 69/227 (30%), Gaps = 45/227 (19%)
Query: 494 CNPNPCPANELCEVNRKGCPSGDPCLPYFCVQGCKLGEASDFIVRQGTLIQVPSSAGEVG 553
C P+PC + GC S C P C C VP V
Sbjct: 56 CEPSPC---------QSGCTSS--CTPSCCQPACCASSPCQ------QACCVPVCCKPVC 98
Query: 554 CYKICSCGQSGLLE--NCMEMHCID--LQKSCIVGGKRKSHGTSFSIDCNVCSCFAGNLV 609
C CS S + +C C Q+SC V + C C
Sbjct: 99 CLPTCSKDSSSCCQQSSCQPTCCASSSCQQSCCV-----------PVCCKPVCCVPTCSE 147
Query: 610 CSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFG 669
S+ C +HSS T PC +VPVC + P C+ C G
Sbjct: 148 DSSSCC--QHSSCQPT-CCTSSPCQ-QSCYVPVCCKPVCFKPICCVPVCSGAST------ 197
Query: 670 SCMSKDPCNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLAC 716
SC + C P C C P V L + C CVP C
Sbjct: 198 SCCQQSSCQP-ACCTTSCCRPSSSVSLLC--RPICRPACCVPISSCC 241
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 41.2 bits (95), Expect = 0.005
Identities = 37/127 (29%), Positives = 53/127 (41%), Gaps = 30/127 (23%)
Query: 494 CNPNPCPANELCEVNRKGCPSGDPCLPYFCVQGCKLGEASDFIVRQGTLIQVPSSAGEVG 553
CNP PC A GCP+G + C C SD +++G + Q +
Sbjct: 4053 CNPMPCEA---------GCPAGMEVVT--CANRCPR-RCSD--LQEGIVCQ-----DDQV 4093
Query: 554 CYKICSCGQSGLLEN--CMEM---HCIDLQKSCIVGGKRKSHGTSFSIDCNVCSCFAGNL 608
C K C C + L ++ C+ + C D Q G + G+ CN CSC AG L
Sbjct: 4094 CQKGCRCPKGSLEQDGGCVPIGHCDCTDAQ------GHSWAPGSQHQDACNNCSCQAGQL 4147
Query: 609 VCSTRLC 615
C+ + C
Sbjct: 4148 SCTAQPC 4154
Score = 37.0 bits (84), Expect = 0.090
Identities = 37/128 (28%), Positives = 51/128 (39%), Gaps = 23/128 (17%)
Query: 493 PCNPNPCPANELCEVNRKGCPSGDPC---LPYFCVQGCKLGEASDFIVRQGTLIQVPSSA 549
PC PC CE+ R S D C L C C +A+ S +
Sbjct: 2603 PCGLQPCSGGTDCELGRVYV-SADLCQKGLVPPCPPSCLDPKANR------------SCS 2649
Query: 550 GEVGCYKICSCGQSGLLENCMEMHCIDLQKS-CIVGGKRKSHGTSFSI-DCNVCSCFAGN 607
G C + C C LL + C+ L + C+VG + K G SF + +C+ C C G
Sbjct: 2650 GH--CVEGCRCPPGLLLH---DTRCLPLSECPCLVGEELKWPGVSFLLGNCSQCVCEKGE 2704
Query: 608 LVCSTRLC 615
L+C C
Sbjct: 2705 LLCQPGGC 2712
Score = 36.6 bits (83), Expect = 0.12
Identities = 34/131 (25%), Positives = 46/131 (35%), Gaps = 28/131 (21%)
Query: 491 THPCNPNPC----PANELCEVNRKGCPSGDPCLPYFCVQGCKLGEASDFIVRQGTLIQVP 546
T CN PC P N L + G PC P C L Q P
Sbjct: 2874 TRDCNTQPCTAQCPENMLFRSAEQCHQEGGPC-PRLC------------------LTQGP 2914
Query: 547 SSAGEVGCYKICSCGQSGLLENCMEMHCIDL-QKSCIVGGKRKSHGTSFSID-CNVCSCF 604
C C+C L N C+ Q C + G+ + G +D CN C+C
Sbjct: 2915 GIECTGFCAPGCTCPPGLFLHNAS---CLPRSQCPCQLHGQLYASGAMARLDSCNNCTCV 2971
Query: 605 AGNLVCSTRLC 615
+G + C++ C
Sbjct: 2972 SGKMACTSERC 2982
Score = 34.3 bits (77), Expect = 0.58
Identities = 41/157 (26%), Positives = 61/157 (38%), Gaps = 36/157 (22%)
Query: 546 PSSAGEVG-CYKICSCGQSGLLENCMEMHCIDLQKS-CIVGGKRKSHGTSFSIDCNVCSC 603
P GE+G C C+C GLL + E C+ C +G +R + G++ +CN C C
Sbjct: 847 PEDCGELGSCVAGCNC-PLGLLWD-PEGQCVPPSLCPCQLGARRYAPGSATMKECNRCIC 904
Query: 604 FAGNL-VCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVG-L 661
L C+ R C S+ C + P AC+ C
Sbjct: 905 QERGLWNCTARHCPSQ----------------------AFCPRELVYAPGACLLTCDSPS 942
Query: 662 QDHQFEFGS---CMSKDPCNPNPCQKNQRCIPKPQVC 695
+H GS C+ C P ++RC+P P +C
Sbjct: 943 ANHSCPAGSTDGCV----CPPGTVLLDERCVP-PDLC 974
Score = 33.9 bits (76), Expect = 0.76
Identities = 44/180 (24%), Positives = 60/180 (33%), Gaps = 43/180 (23%)
Query: 552 VGCYKICSCGQSGLLEN--CMEMHCIDLQKSCIVGGKRKSH--GTSFSIDCNVCSCFAGN 607
V C + C C + LL C+E SC R S G+ DC C+C G
Sbjct: 1306 VACVEGCFCPEGTLLHGGACLE------PASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQ 1359
Query: 608 LVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQDHQFE 667
C H E L CA+ +C +NG P + D+Q +
Sbjct: 1360 WHCGGD---GGHCEE--------LVPACAEGEA-LCQENGHCVPHGWLC------DNQDD 1401
Query: 668 FGSCMSKDPCNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLACDQVQDPVCDTD 727
G ++ C C + Q CS C+P L CD+ D TD
Sbjct: 1402 CGDGSDEEGCAAPGCGEGQMT---------------CSSGHCLPLALLCDRQDDCGDGTD 1446
Score = 32.7 bits (73), Expect = 1.7
Identities = 69/303 (22%), Positives = 93/303 (30%), Gaps = 89/303 (29%)
Query: 473 PLDTYLRPSTLGNIVEEVTHPCNPNPCPANEL----CEVNRKGC----------PSGDPC 518
P D L S P PCP N C+ N C P G PC
Sbjct: 3483 PCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPC 3542
Query: 519 LPYFCVQGCKLGEASDFIVRQGTLIQVPSSAGEVGCYKICSCGQSGLLENCM---EMHCI 575
P C + G++ Q G VGC C C L ++ + HC
Sbjct: 3543 -PRSCQD-----------LSPGSVCQ----PGSVGCQPTCGCPLGQLSQDGLCVPPAHCR 3586
Query: 576 DLQKSCIVG---GKRKSHGTSFSI------------DCNVCSCFAGNLVCSTRLCLSEHS 620
+ +G + +S G+ FS C+ C+C AG L C
Sbjct: 3587 CQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQC---------- 3636
Query: 621 SEDDRRTFTGLPCNCADQFVPVCGQNGRTYP----SACIARCVGLQDHQFEFGSCMSKDP 676
Q VP C G C C G Q C ++ P
Sbjct: 3637 -----------------QEVPDCPDPGVWSSWGPWEDCSVSCGG--GEQLRSRRC-ARPP 3676
Query: 677 CNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQ---LACDQVQDPV-CDTDHMEHN 732
C P P ++++ C QVC G EC P + +C V V C ++ E
Sbjct: 3677 C-PGPARQSRTC--STQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEG 3733
Query: 733 NLC 735
C
Sbjct: 3734 CHC 3736
Score = 32.0 bits (71), Expect = 2.9
Identities = 52/199 (26%), Positives = 70/199 (35%), Gaps = 49/199 (24%)
Query: 491 THPCNPNPCPANELCEVNRKGCPSGDPCLPYFCVQGCKLGEASDFIVRQGTLIQVPSSAG 550
T PC + CP N C G PC P C C D I Q T G
Sbjct: 1799 TKPCPQDGCP-NATCS----GELMFQPCAP--CPLTC------DDISGQVTC-PPDWPCG 1844
Query: 551 EVGCYKICSCGQSGLLENCMEMHCI-DLQKSCIVGGKRKSHGTSFSIDCNVCSCFAGNLV 609
GC+ C + +L + E C+ Q C+V G R G DC +C C
Sbjct: 1845 SPGCW----CPEGQVLGS--EGWCVWPRQCPCLVDGARYWPGQRIKADCQLCIC------ 1892
Query: 610 CSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFG 669
+D R L +CA CG + + + C+ C G Q Q+ F
Sbjct: 1893 ------------QDGRPRRCRLNPDCAVD----CGWSSWSPWAKCLGPC-GSQSIQWSFR 1935
Query: 670 SCMSKDPCNPNPCQKNQRC 688
S NP P + ++C
Sbjct: 1936 SSN-----NPRPSGRGRQC 1949
Score = 32.0 bits (71), Expect = 2.9
Identities = 38/139 (27%), Positives = 48/139 (34%), Gaps = 33/139 (23%)
Query: 610 CSTRLCLSE---HSSEDDRRTFTGLPCNCAD-QFVPV----CGQNGRTYP---SACIARC 658
CS R+ + + H R G PC D F P C ++ T P AC + C
Sbjct: 4377 CSCRVLVQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPC 4436
Query: 659 VGLQDHQFEFGSCMSKDPCNPN-PCQKN-----QRCIPKPQVC-------------LTTF 699
GL C PC P C K CIP P+ C L
Sbjct: 4437 AGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIP-PEECNCWHTSAAGAGMTLAPG 4495
Query: 700 DK--FGCSQYECVPRQLAC 716
D+ GC + EC +L C
Sbjct: 4496 DRLQLGCKECECRRGELHC 4514
Score = 30.4 bits (67), Expect = 8.4
Identities = 18/63 (28%), Positives = 24/63 (38%), Gaps = 10/63 (15%)
Query: 701 KFGCSQYECVPRQLACDQVQDPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQ--PFCRATE 758
+F C EC PR CDQ +D +D C + PC P C + E
Sbjct: 1569 EFRCGSGECTPRGWRCDQEEDCADGSDERGCGGPCA--------PHHAPCARGPHCVSPE 1620
Query: 759 PVC 761
+C
Sbjct: 1621 QLC 1623
>gi|63053512 keratin associated protein 10-1 [Homo sapiens]
Length = 282
Score = 41.2 bits (95), Expect = 0.005
Identities = 45/167 (26%), Positives = 59/167 (35%), Gaps = 36/167 (21%)
Query: 677 CNPNPCQK--NQRCIP--------KPQVCLTTFDKFGCSQYECVPRQLACDQVQD-PVCD 725
C P+PCQ C P +P C ++ C Q CVP + C V P C
Sbjct: 62 CEPSPCQSGCTSSCTPSCCQQSSCQPACCTSS----PCQQACCVP--VCCKPVCCLPTCS 115
Query: 726 TDHME--HNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGHNGETYSSVCAAYSDRVAVDY 783
D + C S S + C P C +PVC Y C+ D +
Sbjct: 116 KDSSSCCQQSSCQPTCCASSSSQQSCCVPVC--CKPVC------YVPTCS--EDSSSCCQ 165
Query: 784 YGDCQAVGVLSEHSSVAECASVKCPSLLAAGCKPIIPPGACCPLCAG 830
C S A C V+C + CKPI C P+C+G
Sbjct: 166 QSSCHPACCTSSPCQQACCVPVRCKPVC---CKPI----CCVPVCSG 205
Score = 38.1 bits (87), Expect = 0.040
Identities = 69/283 (24%), Positives = 88/283 (31%), Gaps = 80/283 (28%)
Query: 567 ENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCNVCSCFAGNLVCSTRLCLSEHSSEDDRR 626
E+C E HC L SC C C LVC+ +S SS +
Sbjct: 24 ESCCEPHCCAL--SC----------------CAPAPCLT--LVCTP---VSRVSSPCCQA 60
Query: 627 TFTGLPCN--CADQFVPVCGQNGRTYPSACIARCVGLQDHQFEFGSCMSKDPCNPNPCQK 684
PC C P C Q S+C C C +PCQ+
Sbjct: 61 ACEPSPCQSGCTSSCTPSCCQQ-----SSCQPAC------------------CTSSPCQQ 97
Query: 685 NQRCIP---KPQVCLTTFDKFG---CSQYECVPRQLACDQVQD---------PVC--DTD 727
C+P KP CL T K C Q C P A Q PVC T
Sbjct: 98 -ACCVPVCCKPVCCLPTCSKDSSSCCQQSSCQPTCCASSSSQQSCCVPVCCKPVCYVPTC 156
Query: 728 HMEHNNLCTLYQRGKSLSYKGPCQPFCRAT---EPVCGHNGETYSSVCAAYSDRVAVDYY 784
+ ++ C + PCQ C +PVC VC+ S
Sbjct: 157 SEDSSSCCQQSSCHPACCTSSPCQQACCVPVRCKPVCC-KPICCVPVCSGASTSC----- 210
Query: 785 GDCQAVGVLSEHSSVAECASVKCPSLLAAGCKPIIPPGACCPL 827
CQ + + C SLL C+P+ P C P+
Sbjct: 211 --CQQSSCQPACCTTSCCRPSSSVSLL---CRPVCRPACCMPV 248
>gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens]
Length = 955
Score = 41.2 bits (95), Expect = 0.005
Identities = 74/306 (24%), Positives = 106/306 (34%), Gaps = 60/306 (19%)
Query: 550 GEVGCYKI-CSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSI---DCNVCSCFA 605
G+V C K+ C S + + + C C G ++ G FS +C VC C A
Sbjct: 412 GKVTCEKVRCEAACSHPIPS-RDGGCCPSCTGCFHSGVVRAEGDVFSPPNENCTVCVCLA 470
Query: 606 GNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPV-CGQNGRTYPSACI--------A 656
GN+ C + C S + C C VPV C +GR Y +
Sbjct: 471 GNVSCISPECPSGPCQTPPQTDC----CTC----VPVRCYFHGRWYADGAVFSGGGDECT 522
Query: 657 RCVGLQDHQFEFGSCMSKDPCNPNPCQKNQRCIPKPQVCLTTFD---KFGCSQYECVPRQ 713
CV Q+ + E S PC C + + + Q C T + GCS + +
Sbjct: 523 TCV-CQNGEVE----CSFMPCPELACPREEWRLGPGQCCFTCQEPTPSTGCS-LDDNGVE 576
Query: 714 LACDQVQDP-------VCDTD-HMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCG--- 762
Q+ P +C D + + + G C P C A G
Sbjct: 577 FPIGQIWSPGDPCELCICQADGSVSCKRTDCVDSCPHPIRIPGQCCPDCSAGCTYTGRIF 636
Query: 763 HNGETYSSVCAAYSDRVAVDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGCKPIIPPG 822
+N ET+ SV + + SVA C+ V CP P P G
Sbjct: 637 YNNETFPSVLD--------------PCLSCICLLGSVA-CSPVDCPITCT---YPFHPDG 678
Query: 823 ACCPLC 828
CCP+C
Sbjct: 679 ECCPVC 684
Score = 37.4 bits (85), Expect = 0.069
Identities = 68/304 (22%), Positives = 91/304 (29%), Gaps = 58/304 (19%)
Query: 574 CIDLQKSCIVGGKRKSHGTSFS---IDCNVCSCFAGNLVCSTRLCLSEHSSEDDRRTFTG 630
C + C G+ + G FS +C C C G + CS C ++ R G
Sbjct: 494 CTCVPVRCYFHGRWYADGAVFSGGGDECTTCVCQNGEVECSFMPCPELACPREEWRLGPG 553
Query: 631 LPCNCADQFVPVCG----QNGRTYPSACI-------ARCVGLQDHQFEFGSCMSKDPCNP 679
C + P G NG +P I C+ D D C P
Sbjct: 554 QCCFTCQEPTPSTGCSLDDNGVEFPIGQIWSPGDPCELCICQADGSVSCKRTDCVDSC-P 612
Query: 680 NPCQKNQRCIPKPQVCLT----------TFDKF--GCSQYECVPRQLACDQVQDPVCDTD 727
+P + +C P T TF C C+ +AC V P+ T
Sbjct: 613 HPIRIPGQCCPDCSAGCTYTGRIFYNNETFPSVLDPCLSCICLLGSVACSPVDCPITCTY 672
Query: 728 HMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGHNGETYSSVCAAYSDRVAVDYYGDC 787
+ G C P CR C + G A +D
Sbjct: 673 PFHPD---------------GECCPVCRD----CNYEGRK-----VANGQVFTLDDEPCT 708
Query: 788 QAVGVLSEHSSVAECASVKCPSLLAAGCKPIIPPGACCPLCAGMLRVLFDKEKLDTIAKV 847
+ L E S C V C A P + PG CC C L L +K+ L V
Sbjct: 709 RCTCQLGEVS----CEKVPCQRACA---DPALLPGDCCSSCPDSLSPLEEKQGLSPHGNV 761
Query: 848 TNKK 851
K
Sbjct: 762 AFSK 765
>gi|126012573 low density lipoprotein-related protein 2 [Homo
sapiens]
Length = 4655
Score = 40.8 bits (94), Expect = 0.006
Identities = 46/191 (24%), Positives = 71/191 (37%), Gaps = 40/191 (20%)
Query: 549 AGEVGCYKICSCGQSGLLENCMEMHCI------DLQKSCIVGGKRKSHGTSFSIDCNVCS 602
A E+GC + +C Q G + E CI D + C G + DC+ +
Sbjct: 57 ADEIGC-AVVTC-QQGYFKCQSEGQCIPNSWVCDQDQDCDDGSDERQ-------DCSQST 107
Query: 603 CFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQ 662
C + + CS C+ D R +C D +N YP+ C
Sbjct: 108 CSSHQITCSNGQCIPSEYRCDHVR-------DCPDG----ADENDCQYPTCEQLTC---- 152
Query: 663 DHQFEFGSCMS-KDPCNPN-PCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLACDQVQ 720
+ G+C + C+ C+ + I ++CL ++F C EC+PR CD
Sbjct: 153 ----DNGACYNTSQKCDWKVDCRDSSDEINCTEICL--HNEFSCGNGECIPRAYVCDHDN 206
Query: 721 DPVCDTDHMEH 731
D C EH
Sbjct: 207 D--CQDGSDEH 215
Score = 38.9 bits (89), Expect = 0.024
Identities = 48/215 (22%), Positives = 74/215 (34%), Gaps = 45/215 (20%)
Query: 598 CNVCSCFAGNLVCSTRLCLSEH---SSEDDRRTFTGLPCNC--------ADQFVPVCGQN 646
C +C + C++ C+ +H E D + P +C AD+F C
Sbjct: 2859 CTTHTCSSSEFQCASGRCIPQHWYCDQETDCFDASDEPASCGHSERTCLADEFK--C-DG 2915
Query: 647 GRTYPSACIAR----CVGLQD----HQFEFGSCMSKDPCNPNPCQKNQRCIPKPQVCLTT 698
GR PS I C + D HQ + +C + N ++RCIP+ VC
Sbjct: 2916 GRCIPSEWICDGDNDCGDMSDEDKRHQCQNQNCSDSEFLCVNDRPPDRRCIPQSWVCDGD 2975
Query: 699 FD-------------------KFGCSQYECVPRQLACDQVQDPVCDTDHMEHNNLCTLYQ 739
D +F C C+P+ CD+ D C E L Q
Sbjct: 2976 VDCTDGYDENQNCTRRTCSENEFTCGYGLCIPKIFRCDRHND--CGDYSDERGCLYQTCQ 3033
Query: 740 RGKSLSYKGPC--QPFCRATEPVCGHNGETYSSVC 772
+ + G C + F + CG + +C
Sbjct: 3034 QNQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLC 3068
Score = 37.4 bits (85), Expect = 0.069
Identities = 80/377 (21%), Positives = 114/377 (30%), Gaps = 86/377 (22%)
Query: 403 KKCQPEMWKAIACS-----LQIKPCHSKSR----GSIICKSD-CVEILKKCGDQNKFPED 452
K+C PE W+ + H SR G C + C+ KC N D
Sbjct: 3604 KRCIPESWQCDTFNDCEDNSDEDSSHCASRTCRPGQFRCANGRCIPQAWKCDVDNDCG-D 3662
Query: 453 HTAESICELLSPTDDLKN-----------CIP-------LDTYLRPSTLGNIVEEVTHPC 494
H+ E I E +S N CIP +D S E HP
Sbjct: 3663 HSDEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERTCHPV 3722
Query: 495 NPNPCPANELCEVNRKGCPSGDPCLPYFCVQGCKLGEASDFIVRQGTLIQVPSSAGEVGC 554
C N C R C + C + C E ++ R +PS C
Sbjct: 3723 GDFRCK-NHHCIPLRWQCDGQNDCGDNSDEENCAPRECTESEFRCVNQQCIPS---RWIC 3778
Query: 555 YKICSCGQSGLLENCMEM-------------HCIDLQKSCIVGGKRKSHGTSFSIDCNV- 600
CG + +C EM HC+ + C G S DC
Sbjct: 3779 DHYNDCGDNSDERDC-EMRTCHPEYFQCTSGHCVHSELKC--DGSADCLDASDEADCPTR 3835
Query: 601 ----CSCFAGNLVCSTRLCLSEH-----------SSEDDRRTFTGLPCNCADQFVPVCGQ 645
C A C +C+ + S+++ +PCN ++F C
Sbjct: 3836 FPDGAYCQATMFECKNHVCIPPYWKCDGDDDCGDGSDEELHLCLDVPCNSPNRFR--CDN 3893
Query: 646 NGRTYPSACIARCVGLQDHQFEFGSCMSKDPCNPNPCQKNQRCI-PKPQVCLTTFDKFGC 704
N RC+ + C D C + + C P P+ C T ++ C
Sbjct: 3894 N----------RCI------YSHEVCNGVDDCGDGTDETEEHCRKPTPKPC--TEYEYKC 3935
Query: 705 SQYECVPRQLACDQVQD 721
C+P CD D
Sbjct: 3936 GNGHCIPHDNVCDDADD 3952
Score = 34.7 bits (78), Expect = 0.45
Identities = 50/215 (23%), Positives = 65/215 (30%), Gaps = 50/215 (23%)
Query: 556 KICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCNVCSCFAGNLVCSTRLC 615
+ C GQ C + +C Q C + C C + C+ + C
Sbjct: 3551 RFCRLGQF----QCSDGNCTSPQTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCANKRC 3606
Query: 616 LSEHSSEDDRRTFTGLPCNCADQFVPVCGQ-----------NGRTYPSACIAR----CVG 660
+ E D TF N +D+ C NGR P A C
Sbjct: 3607 IPESWQCD---TFNDCEDN-SDEDSSHCASRTCRPGQFRCANGRCIPQAWKCDVDNDCGD 3662
Query: 661 LQDHQFEFGSCMSK----DPCNPNPCQKNQRCIPKPQVCLTTFD---------------- 700
D E CMS D C+ N RCIPK VC D
Sbjct: 3663 HSDEPIE--ECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERTCH 3720
Query: 701 ---KFGCSQYECVPRQLACDQVQDPVCDTDHMEHN 732
F C + C+P + CD D C + E N
Sbjct: 3721 PVGDFRCKNHHCIPLRWQCDGQND--CGDNSDEEN 3753
Score = 31.6 bits (70), Expect = 3.8
Identities = 65/265 (24%), Positives = 88/265 (33%), Gaps = 73/265 (27%)
Query: 491 THPCNPNP------CP--ANELCEVNRKGC--PSGDPCLPYFCVQGCKLGEASDFIVRQG 540
+H C P P CP N NRK C +G+ C AS F G
Sbjct: 2663 SHICAPGPNGAECQCPHEGNWYLANNRKHCIVDNGERC------------GASSFTCSNG 2710
Query: 541 TLIQVPSSAGEVGCYKICSCGQ-SGLLENCMEMH-CIDLQKSCIVGG-KRKSHGTSFSID 597
I + E C CG S +E+ +H C +C G + S+ + D
Sbjct: 2711 RCI-----SEEWKCDNDNDCGDGSDEMESVCALHTCSPTAFTCANGRCVQYSYRCDYYND 2765
Query: 598 CNVCSCFAGNL----------VCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNG 647
C S AG L +C+ R C+ R F CN D C N
Sbjct: 2766 CGDGSDEAGCLFRDCNATTEFMCNNRRCIP--------REFI---CNGVDN----CHDNN 2810
Query: 648 RTYPSACIARCVGLQDHQFEFGSCMSKDPCNP--------NPCQKNQRCIPKPQVCLT-- 697
+ C R Q + C + + C P N C N P C T
Sbjct: 2811 TSDEKNCPDRTC-----QSGYTKCHNSNICIPRVYLCDGDNDCGDNSD--ENPTYCTTHT 2863
Query: 698 -TFDKFGCSQYECVPRQLACDQVQD 721
+ +F C+ C+P+ CDQ D
Sbjct: 2864 CSSSEFQCASGRCIPQHWYCDQETD 2888
Score = 31.6 bits (70), Expect = 3.8
Identities = 51/263 (19%), Positives = 82/263 (31%), Gaps = 40/263 (15%)
Query: 494 CNPNPCPANELCEVNRKGCPSGDPCLPYFCVQG--------CKLGEASDFIVRQGTLIQV 545
C+ C + E N C G + C C G + R
Sbjct: 2707 CSNGRCISEEWKCDNDNDCGDGSDEMESVCALHTCSPTAFTCANGRCVQYSYRCDYYNDC 2766
Query: 546 PSSAGEVGC-YKICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCNVCSCF 604
+ E GC ++ C+ + C CI + C + TS +C +C
Sbjct: 2767 GDGSDEAGCLFRDCNATTEFM---CNNRRCIPREFICNGVDNCHDNNTSDEKNCPDRTCQ 2823
Query: 605 AGNLVC-STRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVGLQD 663
+G C ++ +C+ D CG N P+ C +
Sbjct: 2824 SGYTKCHNSNICIPRVYLCDGDND---------------CGDNSDENPTYCTTHTCSSSE 2868
Query: 664 HQFEFGSCMSKD-PCNP-----NPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLACD 717
Q G C+ + C+ + + C + CL D+F C C+P + CD
Sbjct: 2869 FQCASGRCIPQHWYCDQETDCFDASDEPASCGHSERTCLA--DEFKCDGGRCIPSEWICD 2926
Query: 718 QVQD--PVCDTD--HMEHNNLCT 736
D + D D H N C+
Sbjct: 2927 GDNDCGDMSDEDKRHQCQNQNCS 2949
Score = 31.2 bits (69), Expect = 4.9
Identities = 45/193 (23%), Positives = 63/193 (32%), Gaps = 43/193 (22%)
Query: 600 VCSCFAGNLVCSTRLCLSEHSSEDDRRTFTGL---PCNCADQFVPVCGQNGRTYPSACIA 656
VC C G + S L + + GL PC +NGR P+ +
Sbjct: 997 VCGCPYGMRLASNHLTCEGDPTNEPPTEQCGLFSFPC-----------KNGRCVPNYYL- 1044
Query: 657 RCVGLQDHQFEFGSCMSKDPCNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLAC 716
C D C+ N Q C C ++ F C EC+P C
Sbjct: 1045 --------------CDGVDDCHDN--SDEQLCGTLNNTCSSS--AFTCGHGECIPAHWRC 1086
Query: 717 DQVQDPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPF-CRATEPVCGHNGETYSSVCAAY 775
D+ D V +D EHN C + L + C C + VC + + C
Sbjct: 1087 DKRNDCVDGSD--EHN--CPTHAPASCLDTQYTCDNHQCISKNWVCDTDND-----CGDG 1137
Query: 776 SDRVAVDYYGDCQ 788
SD + CQ
Sbjct: 1138 SDEKNCNSTETCQ 1150
Score = 31.2 bits (69), Expect = 4.9
Identities = 26/86 (30%), Positives = 32/86 (37%), Gaps = 24/86 (27%)
Query: 702 FGCSQYECVPRQLACDQVQDPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVC 761
F CS C+ + CD D +D ME ++C L+ C T C
Sbjct: 2705 FTCSNGRCISEEWKCDNDNDCGDGSDEME--SVCALHT--------------CSPTAFTC 2748
Query: 762 GHNGETYSSVCAAYSDRVAVDYYGDC 787
NG C YS R DYY DC
Sbjct: 2749 A-NGR-----CVQYSYR--CDYYNDC 2766
Score = 31.2 bits (69), Expect = 4.9
Identities = 39/193 (20%), Positives = 56/193 (29%), Gaps = 50/193 (25%)
Query: 569 CMEMHCIDLQKSCIVGGKRKSHGTSFSIDCNVCSCFAGNLVCSTRLCL------------ 616
C CI C + + S C +C G C+ C+
Sbjct: 3601 CANKRCIPESWQCDTFNDCEDNSDEDSSHCASRTCRPGQFRCANGRCIPQAWKCDVDNDC 3660
Query: 617 SEHSSEDDRRTFTGLPCNCADQFVPV-CGQNGRTYPSACIARCVGLQDHQFEFGSCMSKD 675
+HS E + + D F C N R P + C G+ D + +
Sbjct: 3661 GDHSDEPIEECMSS--AHLCDNFTEFSCKTNYRCIPKWAV--CNGVDDCRDN----SDEQ 3712
Query: 676 PCNPNPCQ-------KNQRCIP--------------------KPQVCLTTFDKFGCSQYE 708
C C KN CIP P+ C T +F C +
Sbjct: 3713 GCEERTCHPVGDFRCKNHHCIPLRWQCDGQNDCGDNSDEENCAPREC--TESEFRCVNQQ 3770
Query: 709 CVPRQLACDQVQD 721
C+P + CD D
Sbjct: 3771 CIPSRWICDHYND 3783
>gi|93102379 low density lipoprotein-related protein 1B precursor
[Homo sapiens]
Length = 4599
Score = 39.7 bits (91), Expect = 0.014
Identities = 55/253 (21%), Positives = 79/253 (31%), Gaps = 58/253 (22%)
Query: 603 CFAGNLVCSTRLCLS------------EHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTY 650
C AG C R C+ + S ED F +C D QN R
Sbjct: 845 CKAGEFRCKNRHCIQARWKCDGDDDCLDGSDEDSVNCFNH---SCPDDQFKC--QNNRCI 899
Query: 651 PSACIARCVGLQDHQFEFGSCMSKDPCNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECV 710
P + C G D C N + NQ C + D+F C C+
Sbjct: 900 PKRWL--CDGAND-------------CGSNEDESNQTCTART----CQVDQFSCGNGRCI 940
Query: 711 PRQLACDQVQDPVCDTDHMEHNNLCT-------LYQRGKSLSYKGPCQPFCRATEPVCGH 763
PR CD+ D TD M T + + G+ +S K C ++ CG
Sbjct: 941 PRAWLCDREDDCGDQTDEMASCEFPTCEPLTQFVCKSGRCISSKWHCD-----SDDDCGD 995
Query: 764 NGETYSSVCAAYSDRV------AVDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGCK- 816
+ V + + ++ + + C + S A+ K AGC
Sbjct: 996 GSDEVGCVHSCFDNQFRCSSGRCIPGHWACDGDNDCGDFSDEAQINCTKEEIHSPAGCNG 1055
Query: 817 ---PIIPPGACCP 826
P G C P
Sbjct: 1056 NEFQCHPDGNCVP 1068
Score = 38.5 bits (88), Expect = 0.031
Identities = 82/355 (23%), Positives = 116/355 (32%), Gaps = 87/355 (24%)
Query: 496 PNPCPANELCEVNRKGCPSGDPCLPYFCVQGCK-LGEASDFIVRQGTLIQVPSSAGEVGC 554
P+ CP C+ R C +G LP F G G+ SD E+ C
Sbjct: 3349 PDDCPEFR-CQPGRFQCGTGLCALPAFICDGENDCGDNSD----------------ELNC 3391
Query: 555 -YKICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCNVCSCFAGNLVC-ST 612
+C GQ +N CI + C G+ DC SC C +T
Sbjct: 3392 DTHVCLSGQFKCTKN---QKCIPVNLRC--NGQDDCGDEEDERDCPENSCSPDYFQCKTT 3446
Query: 613 RLCLSEH--SSEDDRRTFTGLPCNCADQFVPVCGQNG-RTYPSACIA---RCVGLQDHQF 666
+ C+S+ ED NC + CG + + + CI RC D Q
Sbjct: 3447 KHCISKLWVCDEDPDCADASDEANCDKK---TCGPHEFQCKNNNCIPDHWRC----DSQN 3499
Query: 667 EFGSCMSKDPCNPNPCQ------KNQRCIPKPQVCLTTFD-----------------KFG 703
+ ++ C P C N C+ C FD +F
Sbjct: 3500 DCSDNSDEENCKPQTCTLKDFLCANGDCVSSRFWCDGDFDCADGSDERNCETSCSKDQFR 3559
Query: 704 CSQYECVPRQLACDQVQDPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGH 763
CS +C+P + CD +D C + KS P P C + E +C
Sbjct: 3560 CSNGQCIPAKWKCDGHED-------------CKYGEDEKSCE---PASPTCSSREYICAS 3603
Query: 764 NGETYSSVCAAYSDRVAVDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGCKPI 818
+G C + S + +Y DC E V EC + A C PI
Sbjct: 3604 DG------CISASLKCNGEY--DC--ADGSDEMDCVTECKEDQFRCKNKAHCIPI 3648
Score = 37.7 bits (86), Expect = 0.053
Identities = 50/209 (23%), Positives = 74/209 (35%), Gaps = 55/209 (26%)
Query: 601 CSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRT--YPSAC--IA 656
CSC ++ C++++SS CN +F CG NG Y C I
Sbjct: 2489 CSCRGDRILLEDNRCVTKNSS-----------CNAYSEFE--CG-NGECIDYQLTCDGIP 2534
Query: 657 RCVGLQDHQFEFGSCMSKDPCNPNPCQK------NQRCIPKPQVCLTTFD---------- 700
C D + + C C++ N+RCIP ++C D
Sbjct: 2535 HCKDKSDEKLLY--------CENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDC 2586
Query: 701 --------KFGCSQYECVPRQLACDQVQDPVCDTDHMEHNNL-CT-LYQRGKSLSYKGPC 750
+F C+ C+PR C+Q D +D NN CT Y+ G + C
Sbjct: 2587 KVSTCATVEFRCADGTCIPRSARCNQNIDCADASDEKNCNNTDCTHFYKLGVKTTGFIRC 2646
Query: 751 QPFCRATEPVCGHNGETYSSVCAAYSDRV 779
P +G S+ C YSD +
Sbjct: 2647 NSTSLCVLPTWICDG---SNDCGDYSDEL 2672
Score = 36.2 bits (82), Expect = 0.15
Identities = 92/440 (20%), Positives = 138/440 (31%), Gaps = 96/440 (21%)
Query: 336 LTCLADVREPCQLGCRNLTYCTNFNNRPTELFRSCNAQSDQGAMNDMKLWEKGSIKMPFI 395
L C V Q C C N R CN Q D G D + + S +
Sbjct: 3389 LNCDTHVCLSGQFKCTKNQKCIPVNLR-------CNGQDDCGDEEDERDCPENSCSPDYF 3441
Query: 396 NIPVLDIKKCQPEMWKAIACSLQIKPCHSKSRGSIICKSDCVEILKKCGDQNKFPEDHTA 455
K C ++W C + C S + K C +C + N P+
Sbjct: 3442 QCKTT--KHCISKLW---VCD-EDPDCADASDEANCDKKTCGPHEFQCKNNNCIPDHWRC 3495
Query: 456 ESICELLSPTDDLKNCIPLDTYLRPSTL--GNIVE---------EVTHPCNPNPCPANEL 504
+S + S D +NC P L+ G+ V + + C +
Sbjct: 3496 DSQNDC-SDNSDEENCKPQTCTLKDFLCANGDCVSSRFWCDGDFDCADGSDERNCETS-- 3552
Query: 505 CEVNRKGCPSGDPCLP--YFCV--QGCKLGEASDFIVRQGTLIQ----VPSSAGEVGCYK 556
C ++ C +G C+P + C + CK GE + +S G +
Sbjct: 3553 CSKDQFRCSNGQ-CIPAKWKCDGHEDCKYGEDEKSCEPASPTCSSREYICASDGCISASL 3611
Query: 557 ICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCNVCS-------------- 602
C+ G+ + EM C+ K K K+H C+
Sbjct: 3612 KCN-GEYDCADGSDEMDCVTECKEDQFRCKNKAHCIPIRWLCDGIHDCVDGSDEENCERG 3670
Query: 603 ---CFAGNLVCSTRLCLSEH---SSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIA 656
C A +C+ LC EDD CG N P C+
Sbjct: 3671 GNICRADEFLCNNSLCKLHFWVCDGEDD------------------CGDNSDEAPDMCVK 3712
Query: 657 ---------RC----VGLQDHQFEFGSCMSKDPCNPNPCQKN--QRCIPKPQVCLTTFDK 701
RC + LQ Q C D C N + + + K + C D+
Sbjct: 3713 FLCPSTRPHRCRNNRICLQSEQM----CNGIDECGDNSDEDHCGGKLTYKARPCKK--DE 3766
Query: 702 FGCSQYECVPRQLACDQVQD 721
F CS +C+P L CD++ D
Sbjct: 3767 FACSNKKCIPMDLQCDRLDD 3786
Score = 34.3 bits (77), Expect = 0.58
Identities = 92/430 (21%), Positives = 127/430 (29%), Gaps = 116/430 (26%)
Query: 414 ACSLQIKPCHSK-----------------SRGSIICK-SDCVEILKKCGDQNKFPEDHTA 455
+C KPC+++ + + CK S C + +C D P
Sbjct: 2551 SCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDCKVSTCATVEFRCADGTCIPRSARC 2610
Query: 456 ESICELLSPTDDLKNCIPLDTY----LRPSTLGNIVEEVTHPC--------NPNPCP--A 501
+ +D+ KNC D L T G I T C N C +
Sbjct: 2611 NQNIDCADASDE-KNCNNTDCTHFYKLGVKTTGFIRCNSTSLCVLPTWICDGSNDCGDYS 2669
Query: 502 NEL---------CEVNRKGCPSGDPCLPYFCVQGCKLGEASDFIVRQGTLIQVPSSAGEV 552
+EL CE N CPSG L + G K E
Sbjct: 2670 DELKCPVQNKHKCEENYFSCPSGRCILNTWICDGQK---------------DCEDGRDEF 2714
Query: 553 GCYKICSCGQSGL-LENCMEMHCI-DLQKSCIVGGKRKSHGTSFSIDCNVCSCFAGNLVC 610
C CS Q + C+ H I D + C G S C +C A C
Sbjct: 2715 HCDSSCSWNQFACSAQKCISKHWICDGEDDC---GDGLDESDSI---CGAITCAADMFSC 2768
Query: 611 -STRLCLSEH----------SSEDDRRTFTGLPCNCAD--------------QFV----P 641
+R C+ H D+ T P N D QFV
Sbjct: 2769 QGSRACVPRHWLCDGERDCPDGSDELSTAGCAPNNTCDENAFMCHNKVCIPKQFVCDHDD 2828
Query: 642 VCGQNGRTYPSACIARCVGLQDHQFEFGSCMSKD----------PCNPNPCQKNQRCIPK 691
CG P +C G ++ G C+ P + + N +C
Sbjct: 2829 DCGDGSDESPQCGYRQC-GTEEFSCADGRCLLNTQWQCDGDFDCPDHSDEAPLNPKCKSA 2887
Query: 692 PQVCLTTFDKFGCSQYECVPRQLACDQVQDPVCDTDHME-HNNLCTLYQ--------RGK 742
Q C ++F F C C+P CD D +D H N C + +
Sbjct: 2888 EQSCNSSF--FMCKNGRCIPSGGLCDNKDDCGDGSDERNCHINECLSKKVSGCSQDCQDL 2945
Query: 743 SLSYKGPCQP 752
+SYK C P
Sbjct: 2946 PVSYKCKCWP 2955
>gi|29568105 transmembrane protein with EGF-like and two
follistatin-like domains 1 [Homo sapiens]
Length = 380
Score = 39.7 bits (91), Expect = 0.014
Identities = 46/184 (25%), Positives = 68/184 (36%), Gaps = 57/184 (30%)
Query: 584 GGKRKSHGTSFSIDCNVCSCFAGNL-VCSTRLCLSEHSSEDDRRTFTGLPCNCADQ---- 638
GGK KS I+C+ + ++ VC C ++D GL C C Q
Sbjct: 56 GGKGKS------INCSELNVRESDVRVCDESSCKYGGVCKEDG---DGLKCACQFQCHTN 106
Query: 639 FVPVCGQNGRTYPSACIARCVGLQDHQFEFGSCMSKDPCNPN------------------ 680
++PVCG NG TY + C R + HQ E + +++ PC +
Sbjct: 107 YIPVCGSNGDTYQNECFLRRAACK-HQKEI-TVIARGPCYSDNGSGSGEGEEEGSGAEVH 164
Query: 681 -------PCQKNQRCIPKPQV--CLTTFDKFGCSQYECVPRQLACDQVQDPVCDTDHMEH 731
PC+ C + C+ D CS Y +PVC +D +
Sbjct: 165 RKHSKCGPCKYKAECDEDAENVGCVCNID---CSGYSF-----------NPVCASDGSSY 210
Query: 732 NNLC 735
NN C
Sbjct: 211 NNPC 214
Score = 32.7 bits (73), Expect = 1.7
Identities = 19/51 (37%), Positives = 25/51 (49%), Gaps = 5/51 (9%)
Query: 723 VCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATE-PVCGHNGETYSSVC 772
VCD ++ +C + G L K CQ C PVCG NG+TY + C
Sbjct: 76 VCDESSCKYGGVCK--EDGDGL--KCACQFQCHTNYIPVCGSNGDTYQNEC 122
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,871,243
Number of Sequences: 37866
Number of extensions: 2177738
Number of successful extensions: 6080
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 131
Number of HSP's that attempted gapping in prelim test: 5273
Number of HSP's gapped (non-prelim): 768
length of query: 971
length of database: 18,247,518
effective HSP length: 112
effective length of query: 859
effective length of database: 14,006,526
effective search space: 12031605834
effective search space used: 12031605834
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.