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Search of human proteins with 117938251
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117938251 BCL2-associated transcription factor 1 isoform 2
[Homo sapiens]
(869 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117938251 BCL2-associated transcription factor 1 isoform 2 [H... 1750 0.0
gi|169218320 PREDICTED: similar to BCL2-associated transcription... 1724 0.0
gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Hom... 1722 0.0
gi|239756568 PREDICTED: similar to BCL2-associated transcription... 1713 0.0
gi|117938254 BCL2-associated transcription factor 1 isoform 3 [H... 711 0.0
gi|167234419 thyroid hormone receptor associated protein 3 [Homo... 438 e-123
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 105 2e-22
gi|115511057 hypothetical protein LOC256643 [Homo sapiens] 104 3e-22
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 98 3e-20
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 91 6e-18
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 87 5e-17
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 87 5e-17
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 87 5e-17
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 86 1e-16
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 86 2e-16
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 85 3e-16
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 84 6e-16
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 82 3e-15
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 82 3e-15
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 81 4e-15
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 80 8e-15
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 79 1e-14
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 79 2e-14
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 79 2e-14
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 79 2e-14
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 76 2e-13
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 75 3e-13
gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] 75 3e-13
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 73 1e-12
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 72 2e-12
>gi|117938251 BCL2-associated transcription factor 1 isoform 2 [Homo
sapiens]
Length = 869
Score = 1750 bits (4533), Expect = 0.0
Identities = 869/869 (100%), Positives = 869/869 (100%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR 60
MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR
Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR 60
Query: 61 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 120
NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS
Sbjct: 61 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 120
Query: 121 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK 180
QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK
Sbjct: 121 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK 180
Query: 181 SQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSC 240
SQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSC
Sbjct: 181 SQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSC 240
Query: 241 SDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA 300
SDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA
Sbjct: 241 SDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA 300
Query: 301 KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK 360
KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK
Sbjct: 301 KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK 360
Query: 361 EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS 420
EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS
Sbjct: 361 EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS 420
Query: 421 FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEED 480
FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEED
Sbjct: 421 FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEED 480
Query: 481 KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS 540
KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS
Sbjct: 481 KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS 540
Query: 541 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS 600
HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS
Sbjct: 541 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS 600
Query: 601 ESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL 660
ESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL
Sbjct: 601 ESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL 660
Query: 661 RKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRK 720
RKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRK
Sbjct: 661 RKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRK 720
Query: 721 QEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHE 780
QEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHE
Sbjct: 721 QEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHE 780
Query: 781 MKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDK 840
MKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDK
Sbjct: 781 MKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDK 840
Query: 841 YQGDGIVEDEEETMENNEEKKDRRKEEKE 869
YQGDGIVEDEEETMENNEEKKDRRKEEKE
Sbjct: 841 YQGDGIVEDEEETMENNEEKKDRRKEEKE 869
>gi|169218320 PREDICTED: similar to BCL2-associated transcription
factor 1 isoform 2 [Homo sapiens]
Length = 869
Score = 1724 bits (4466), Expect = 0.0
Identities = 859/869 (98%), Positives = 860/869 (98%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR 60
MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR
Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR 60
Query: 61 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 120
NNR MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS
Sbjct: 61 NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 120
Query: 121 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK 180
QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK
Sbjct: 121 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK 180
Query: 181 SQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSC 240
SQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSC
Sbjct: 181 SQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSC 240
Query: 241 SDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA 300
SDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA
Sbjct: 241 SDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA 300
Query: 301 KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK 360
KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK
Sbjct: 301 KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK 360
Query: 361 EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS 420
EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS
Sbjct: 361 EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS 420
Query: 421 FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEED 480
FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN K KETGYVVERPSTTKDKHKEED
Sbjct: 421 FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEED 480
Query: 481 KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS 540
KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS
Sbjct: 481 KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS 540
Query: 541 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS 600
HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS
Sbjct: 541 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS 600
Query: 601 ESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL 660
ESFIQHIVSLVHHVKEQYFKSAAMTL+ERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL
Sbjct: 601 ESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL 660
Query: 661 RKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRK 720
RK TRLAGEERVFKEENQKGDKKLRCDSADLRHDID RRKERSKERGDSKGSRES GSRK
Sbjct: 661 RKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRK 720
Query: 721 QEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHE 780
QEKTPKDYKEYKSYKDDSKHKREQDHS SSSSSASPSSPSSREEKESKKEREEEFKTHHE
Sbjct: 721 QEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHE 780
Query: 781 MKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDK 840
MKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKW HDK
Sbjct: 781 MKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDK 840
Query: 841 YQGDGIVEDEEETMENNEEKKDRRKEEKE 869
YQGDGIVEDEEETMENNEEKKDR KEEKE
Sbjct: 841 YQGDGIVEDEEETMENNEEKKDRCKEEKE 869
>gi|7661958 BCL2-associated transcription factor 1 isoform 1 [Homo
sapiens]
Length = 920
Score = 1722 bits (4460), Expect = 0.0
Identities = 869/920 (94%), Positives = 869/920 (94%), Gaps = 51/920 (5%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY--RSRSRTYSRSRSRDRMYSRDYRRD 58
MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY RSRSRTYSRSRSRDRMYSRDYRRD
Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
Query: 59 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 118
YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
Sbjct: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
Query: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 178
SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
Sbjct: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
Query: 179 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 238
SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
Sbjct: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
Query: 239 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 298
SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
Sbjct: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300
Query: 299 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA 358
PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA
Sbjct: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEA 360
Query: 359 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG 418
SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG
Sbjct: 361 SKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQG 420
Query: 419 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE 478
KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE
Sbjct: 421 KSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKE 480
Query: 479 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS 538
EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS
Sbjct: 481 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS 540
Query: 539 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 598
DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
Sbjct: 541 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 600
Query: 599 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 658
TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
Sbjct: 601 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 660
Query: 659 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 718
TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
Sbjct: 661 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 720
Query: 719 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 778
RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
Sbjct: 721 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 780
Query: 779 HEMKEYSGFAGVSRPRGTF----------------------------------------- 797
HEMKEYSGFAGVSRPRGTF
Sbjct: 781 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT 840
Query: 798 --------HDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED 849
HDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
Sbjct: 841 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED 900
Query: 850 EEETMENNEEKKDRRKEEKE 869
EEETMENNEEKKDRRKEEKE
Sbjct: 901 EEETMENNEEKKDRRKEEKE 920
>gi|239756568 PREDICTED: similar to BCL2-associated transcription
factor 1 [Homo sapiens]
Length = 869
Score = 1713 bits (4436), Expect = 0.0
Identities = 855/869 (98%), Positives = 856/869 (98%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR 60
MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR
Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR 60
Query: 61 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 120
NNR MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS
Sbjct: 61 NNRAMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 120
Query: 121 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK 180
QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGE QEESPLKSK
Sbjct: 121 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGELQEESPLKSK 180
Query: 181 SQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSC 240
SQEEPKDTFEHD SESIDEFNKSSAT GDIWPGLSAYD SPRSPHSPSPIATPPSQSSSC
Sbjct: 181 SQEEPKDTFEHDSSESIDEFNKSSATCGDIWPGLSAYDXSPRSPHSPSPIATPPSQSSSC 240
Query: 241 SDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA 300
SDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA
Sbjct: 241 SDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPA 300
Query: 301 KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK 360
KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK
Sbjct: 301 KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASK 360
Query: 361 EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS 420
EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS
Sbjct: 361 EKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKS 420
Query: 421 FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEED 480
FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN K KETGYVVERPSTTKDKHKEED
Sbjct: 421 FATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNDKHKETGYVVERPSTTKDKHKEED 480
Query: 481 KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS 540
KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS
Sbjct: 481 KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS 540
Query: 541 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS 600
HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS
Sbjct: 541 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS 600
Query: 601 ESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL 660
ESFIQHIVSLVHHVKEQYFKSAAMTL+ERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL
Sbjct: 601 ESFIQHIVSLVHHVKEQYFKSAAMTLSERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL 660
Query: 661 RKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRK 720
RK TRLAGEERVFKEENQKGDKKLRCDSADLRHDID RRKERSKERGDSKGSRES GSRK
Sbjct: 661 RKDTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDHRRKERSKERGDSKGSRESRGSRK 720
Query: 721 QEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHE 780
QEKTPKDYKEYKSYKDDSKHKREQDHS SSSSSASPSSPSSREEKESKKEREEEFKTHHE
Sbjct: 721 QEKTPKDYKEYKSYKDDSKHKREQDHSLSSSSSASPSSPSSREEKESKKEREEEFKTHHE 780
Query: 781 MKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDK 840
MKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKW HDK
Sbjct: 781 MKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWNHDK 840
Query: 841 YQGDGIVEDEEETMENNEEKKDRRKEEKE 869
YQGDGIVEDEEETMENNEEKKDR KEEKE
Sbjct: 841 YQGDGIVEDEEETMENNEEKKDRCKEEKE 869
>gi|117938254 BCL2-associated transcription factor 1 isoform 3 [Homo
sapiens]
Length = 747
Score = 711 bits (1835), Expect = 0.0
Identities = 418/740 (56%), Positives = 466/740 (62%), Gaps = 110/740 (14%)
Query: 235 SQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERS------------------------ 270
S+S S S + S HS K S S S +S RS
Sbjct: 13 SKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYG 72
Query: 271 ----GSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP--------RDESRGRSS 318
G G G RY P+ + RSP + + +P R SR R S
Sbjct: 73 YRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 132
Query: 319 FYPDGGDQETAKTGK-------FLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEG 371
+ + ++ KR +E + + G +++ K K E+ +
Sbjct: 133 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE-GEPQEESPLKSKSQEEPKDTF 191
Query: 372 EWEDQEALDYFSDKES-------GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATA 424
E + E++D F+ + G +++S + +S +T
Sbjct: 192 EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTV 251
Query: 425 -SHRNTEEE---GLKYKSKVSLKGN--RESDGFREEKNYKLKETGYVVERPSTTKDKHKE 478
S +NT + +++ + S G+ S + +N + T ++
Sbjct: 252 HSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP 311
Query: 479 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIAS 538
D++ R + + E K+ K F SPPLHKNLDAREKSTFREESPLRIKMIAS
Sbjct: 312 RDESRGRSSFYPDGGDQETAKTGK----FLKSPPLHKNLDAREKSTFREESPLRIKMIAS 367
Query: 539 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 598
DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS
Sbjct: 368 DSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKS 427
Query: 599 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 658
TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS
Sbjct: 428 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 487
Query: 659 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 718
TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS
Sbjct: 488 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS 547
Query: 719 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 778
RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH
Sbjct: 548 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 607
Query: 779 HEMKEYSGFAGVSRPRGTF----------------------------------------- 797
HEMKEYSGFAGVSRPRGTF
Sbjct: 608 HEMKEYSGFAGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYT 667
Query: 798 --------HDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED 849
HDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED
Sbjct: 668 PKSKKYFLHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED 727
Query: 850 EEETMENNEEKKDRRKEEKE 869
EEETMENNEEKKDRRKEEKE
Sbjct: 728 EEETMENNEEKKDRRKEEKE 747
Score = 677 bits (1748), Expect = 0.0
Identities = 336/338 (99%), Positives = 336/338 (99%), Gaps = 2/338 (0%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY--RSRSRTYSRSRSRDRMYSRDYRRD 58
MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY RSRSRTYSRSRSRDRMYSRDYRRD
Sbjct: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRD 60
Query: 59 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 118
YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV
Sbjct: 61 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 120
Query: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 178
SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK
Sbjct: 121 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 180
Query: 179 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 238
SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS
Sbjct: 181 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 240
Query: 239 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 298
SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS
Sbjct: 241 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS 300
Query: 299 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 336
PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK
Sbjct: 301 PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 338
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/111 (27%), Positives = 48/111 (43%), Gaps = 25/111 (22%)
Query: 735 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFK---------THHEMKEYS 785
+ +S+ + SRS SSS S S SR+++ S + R + + ++Y
Sbjct: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYR 62
Query: 786 GFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKW 836
G+ RP G RGRGRG +Q G GR++ + G P W
Sbjct: 63 NNRGMRRPYG--------------YRGRGRGYYQGGGGRYH--RGGYRPVW 97
Score = 42.0 bits (97), Expect = 0.002
Identities = 52/225 (23%), Positives = 92/225 (40%), Gaps = 26/225 (11%)
Query: 631 TSYQKATEEHSTRQKSPEIHRRIDISP-STLRKHTRLAGEERVFKEENQKGDKKLRCDSA 689
+S K+ + S+R +S R+ S S R ++R +R++ + ++ + R
Sbjct: 10 SSRSKSRSQSSSRSRSRSHSRKKRYSSRSRSRTYSRSRSRDRMYSRDYRRDYRNNR---- 65
Query: 690 DLRHDIDRRRKERSKERG--------------DSKGSRESSGSRKQEKTPKDYKEYKSYK 735
+R R + R +G + + SR R + ++PK + S +
Sbjct: 66 GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVSSQR 124
Query: 736 DDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT---HHEMKEYSGFAGVSR 792
S+ +R SRS SS+S SS + SK+ +E +T E +E S S+
Sbjct: 125 SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQ 184
Query: 793 --PRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRF-NFKKSGSSP 834
P+ TF D + +D + K G G + N +S SP
Sbjct: 185 EEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSP 229
Score = 36.2 bits (82), Expect = 0.14
Identities = 41/195 (21%), Positives = 74/195 (37%), Gaps = 24/195 (12%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
+ +S+ + SRS SSS S S SR+++ + R + + ++Y
Sbjct: 564 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER-------EEEFKTHHEMKEYSGF 616
Query: 63 RGMRRPYGY------RGRGRGYYQG-------GGGRYHRGGYRPVWNRRHSRSPRRGRSR 109
G+ RP G RGR RG + G + + W+ + +P+ +
Sbjct: 617 AGVSRPRGTFFRIRGRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEY--TPKSKKYF 674
Query: 110 SRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG 169
+ V R R R +++ R + SSP K K +G + ++
Sbjct: 675 LHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP--KWTHDKYQGDGIVEDEEETM 732
Query: 170 EPQEESPLKSKSQEE 184
E EE + K ++E
Sbjct: 733 ENNEEKKDRRKEEKE 747
Score = 33.5 bits (75), Expect = 0.88
Identities = 43/186 (23%), Positives = 77/186 (41%), Gaps = 25/186 (13%)
Query: 10 SSRSKSRSQSSSRSRSRS-HSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNR----G 64
+S K+ + S+R +S H R S R ++R +R++ + ++ + R
Sbjct: 460 TSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSAD 519
Query: 65 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKR-RSVSSQRS 123
+R R + R +G + + SR R + ++PK + S +
Sbjct: 520 LRHDIDRRRKERSKERG--------------DSKGSRESSGSRKQEKTPKDYKEYKSYKD 565
Query: 124 RSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQE 183
S+ +R SRS SS+S SS + SK+ +E +T E +E S S+
Sbjct: 566 DSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT---HHEMKEYSGFAGVSR- 621
Query: 184 EPKDTF 189
P+ TF
Sbjct: 622 -PRGTF 626
Score = 30.4 bits (67), Expect = 7.4
Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 20/99 (20%)
Query: 2 GRSNSR---SHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRD 58
GR +R + ++ + S ++ + R + Y +S+ Y RD DY
Sbjct: 631 GRGRARGVFAGTNTGPNNSNTTFQKRPKEEEWDPEYTPKSKKYFLHDDRDD--GVDY--- 685
Query: 59 YRNNRGMRRPYGYRGRGRGYYQGGGGRYH--RGGYRPVW 95
+ RGRGRG +Q G GR++ + G P W
Sbjct: 686 ----------WAKRGRGRGTFQRGRGRFNFKKSGSSPKW 714
>gi|167234419 thyroid hormone receptor associated protein 3 [Homo
sapiens]
Length = 955
Score = 438 bits (1127), Expect = e-123
Identities = 363/970 (37%), Positives = 497/970 (51%), Gaps = 143/970 (14%)
Query: 2 GRSNSRSHS-SRSKSRSQSSSRSRSRS--HSRKKRY--RSRSRTYSRSRSRDRMYSRDYR 56
G +SRS S SRS+SRS S SRSRSRS SRK+R RSRSR+YS + +R+R + R Y+
Sbjct: 10 GSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQ 69
Query: 57 -RDYR-NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGY---RPVW-NRRHSRSPRRGRSRS 110
RD+R +NRG RRPY +RGR RG+Y G +Y+RGGY R W N R + SPRRGRSRS
Sbjct: 70 NRDFRGHNRGYRRPYYFRGRNRGFYPWG--QYNRGGYGNYRSNWQNYRQAYSPRRGRSRS 127
Query: 111 RSPKRRSVSSQRSRSRSRRSYRSS--RSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 168
RSPKRRS S RSRS SR S +SS RS RSSSSRSSS +S+ SKR+ ++EK++ +
Sbjct: 128 RSPKRRS-PSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSKD 186
Query: 169 GEPQEESPLKSKSQEEPKDTF------EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPR 222
P + + ++ E + TF + SES + ++ +G + + SPR
Sbjct: 187 SRPSQAAG-DNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPR 245
Query: 223 --SPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS--GSVGNG 278
SP SP+ + + S +P+ +T S + +SG+ G +G
Sbjct: 246 ERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHG 305
Query: 279 SSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRF 338
S SPS+ SP+ +SP T + + + E S GG A T ++L+
Sbjct: 306 SGSLSPSKKSPVG-----KSPPSTGSTYGSSQKEESAAS-----GG---AAYTKRYLEEQ 352
Query: 339 TDEESRVFLLDRGNTRDKEASKEKGS--EKGRAEGEWEDQEALDYFSDKESGKQKFNDSE 396
E + + NT DKE KEKGS + G +G+ + D F+ K ++ F S+
Sbjct: 353 KTENGKDKEQKQTNT-DKEKIKEKGSFSDTGLGDGKMKS----DSFAPKTDSEKPFRGSQ 407
Query: 397 GDDTEETED-----YRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGF 451
+ D F K + DQ K A + ++ K+ SKV + N+ +
Sbjct: 408 SPKRYKLRDDFEKKMADFHKEEMDDQDKDKAKGRKESEFDDEPKFMSKV-IGANKNQE-- 464
Query: 452 REEKNYKLKETGYVVERPSTTKDKHKEE-DKNSERITVKKETQS-----------PEQ-- 497
EEK+ K + G V P K + EE ++ S KKE + PE+
Sbjct: 465 -EEKSGKWE--GLVYAPPGKEKQRKTEELEEESFPERSKKEDRGKRSEGGHRGFVPEKNF 521
Query: 498 -VKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDD 556
V + K SPP K ++R+K + + P K S + +V ++M D
Sbjct: 522 RVTAYKAVQEKSSSPPPRKTSESRDKLGAKGDFPTG-KSSFSITREAQVNVRMDSFDEDL 580
Query: 557 SNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKE 616
+ L ++R L LVHS KKEQEFRSIF HI+ Q+ +S SE F QHIV++VHHVKE
Sbjct: 581 ARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKE 640
Query: 617 QYFKSAAMTLNERFTSYQK--ATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFK 674
+F S+ MTL+ERFT Y K +E + +KSPEIHRRIDISPST RKH E + +
Sbjct: 641 HHFGSSGMTLHERFTKYLKRGTEQEAAKNKKSPEIHRRIDISPSTFRKHGLAHDEMKSPR 700
Query: 675 EENQKGDKKLRCDSADLRHDIDRRR--KERSKERGDSK---GSRESSGSRKQ--EKTPKD 727
E K + K + D DLR DI+RR+ KER +RG S+ SR+SS SR++ EKT K
Sbjct: 701 EPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSAEKTEKT 760
Query: 728 YKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHE-----MK 782
+K K K KH+R +D SRSSSSS+ S EE + E EE T + K
Sbjct: 761 HKGSKKQK---KHRRARDRSRSSSSSSQSSHSYKAEEYTEETEEREESTTGFDKSRLGTK 817
Query: 783 EYSGFA--GVSRPRGTF------------------------------------------- 797
++ G + G R RGTF
Sbjct: 818 DFVGPSERGGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRNREEEWDPEYTPKS 877
Query: 798 -----HDDRD-DGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQG-DGIVEDE 850
HDDR+ +G D W RGRGRG F RGRGRF F+KS +SPKW HDK+ G +G +ED+
Sbjct: 878 KKYYLHDDREGEGSDKWVSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDD 937
Query: 851 EETMENNEEK 860
E EN EEK
Sbjct: 938 ESGTENREEK 947
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 105 bits (261), Expect = 2e-22
Identities = 119/350 (34%), Positives = 152/350 (43%), Gaps = 53/350 (15%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKK-RYRSRSRTYSRSRSRDRMYSR----DYR 56
GRS+SRS ++R +SRS++ +R R RS SR R RSRSRT +R RSR R +R R
Sbjct: 560 GRSHSRSPATRGRSRSRTPAR-RGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSR 618
Query: 57 RDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-RRGRSRSRSPKR 115
R R P R R R + G R R R SR+P RRGRSRSR+P R
Sbjct: 619 TPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARR--GRSRSRTPARRGRSRSRTPAR 676
Query: 116 RSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEES 175
RS S RSR+ +RR SR+PR SRS S RRG +T + G S
Sbjct: 677 RSGRS-RSRTPARRGRSRSRTPRRGRSRSRS-------LVRRGRSHSRTPQRRGRSGSSS 728
Query: 176 PLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSP----------- 224
K+KS+ + S S E KS +S S +SPRS
Sbjct: 729 ERKNKSRTSQR----RSRSNSSPEMKKSRISS-----RRSRSLSSPRSKAKSRLSLRRSL 779
Query: 225 --HSPSP---IATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGS 279
SP P TPP +S S S P + TP + S S P + S +
Sbjct: 780 SGSSPCPKQKSQTPPRRSRSGSSQP-----KAKSRTPPRRSRSSSSPPPKQKSKT----P 830
Query: 280 SRYSPSQNSPIHHIPSRRSP--AKTIAPQNAPRDESRGRSSFYPDGGDQE 327
SR S S +SP + S P +PQ + + R S + D E
Sbjct: 831 SRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPE 880
Score = 101 bits (251), Expect = 3e-21
Identities = 111/359 (30%), Positives = 147/359 (40%), Gaps = 56/359 (15%)
Query: 2 GRSNSRSHSSRSKSRSQSSSR--SRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDY 59
GRS SR+ + R +SRS++ +R RSRS + +R RSRSRT R RSR R R
Sbjct: 656 GRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVR------ 709
Query: 60 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNR-RHSRSPRRGRSRSRSPKRRSV 118
RG + RGR G + R R R + SP +SR S + RS+
Sbjct: 710 ---RGRSHSRTPQRRGRS----GSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSL 762
Query: 119 SSQRSRSRSRRSYRSSRS-------------PRSSSSRSSSPYSKS--PVSKRRGSQEKQ 163
SS RS+++SR S R S S PR S S SS P +KS P + R S
Sbjct: 763 SSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPP 822
Query: 164 TKKAEGEPQEESPLKSKSQEEPKD-TFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP- 221
K+ P +S S + K T S + + N+ S T S +++SP
Sbjct: 823 PKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTP----QRRSCFESSPD 878
Query: 222 -----RSPH-------SPSPI--ATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSP 267
R+P SP + +TPP QS S S +P HS S SP
Sbjct: 879 PELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSP 938
Query: 268 ERSGSGSVGNGSSRYSPSQNSPIHHIP-----SRRSPAKTIAPQNAPRDESRGRSSFYP 321
R S + S SP N +P SP + P+ PR G S YP
Sbjct: 939 SRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYP 997
Score = 91.3 bits (225), Expect = 4e-18
Identities = 108/346 (31%), Positives = 141/346 (40%), Gaps = 46/346 (13%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRS-----HSRKKRYRSRSRT-----YSRSRSRDRMY 51
GRS SR+ + R SRS+S RSRS SR + R RSR+ +SRSR+ R
Sbjct: 493 GRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQR-- 550
Query: 52 SRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSR 111
R R R R R RGR R GR P R SR+P R RSRSR
Sbjct: 551 -RGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSR--SRTPARRRSRSRTPTRRRSRSR 607
Query: 112 SPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSP-----YSKSPVSKRRGSQEKQTKK 166
+P RR S RSR+ +RR R +RSP SRS SP S+S RRG +T
Sbjct: 608 TPARRGRS--RSRTPARRRSR-TRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPA 664
Query: 167 AEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHS 226
G + +P + + + S S S + + G S HS
Sbjct: 665 RRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRS---------HS 715
Query: 227 PSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQ 286
+P S SSS K+ SQ SPE S SSR S S
Sbjct: 716 RTPQRRGRSGSSS---------ERKNKSRTSQRRSRSNSSPEMKKS----RISSRRSRSL 762
Query: 287 NSPIHHIPSRRSPAKTIAPQN-APRDESRGRSSFYPDGGDQETAKT 331
+SP SR S ++++ + P+ +S+ G Q AK+
Sbjct: 763 SSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKS 808
Score = 88.6 bits (218), Expect = 2e-17
Identities = 103/328 (31%), Positives = 140/328 (42%), Gaps = 25/328 (7%)
Query: 4 SNSRSH--SSRSKSRSQSSSR--SRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDY 59
S +RSH + R KS S + SR RSRS + KR RSRSRT ++ R R S +RR
Sbjct: 459 SKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTK-RGHSRSRSPQWRRSR 517
Query: 60 RNNR-GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSV 118
R G R RGR R + G R R R SRS RRGRS SRSP R
Sbjct: 518 SAQRWGRSRSPQRRGRSRSPQRPGWSRS-----RNTQRRGRSRSARRGRSHSRSPATRGR 572
Query: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSP---YSKSPVSKRRGSQEKQTKKAEGEPQEES 175
S RSR+ +RR SR+P SRS +P S+S RRG +T A + S
Sbjct: 573 S--RSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRT-PARRRSRTRS 629
Query: 176 PLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPS 235
P++ +S+ S S + + S + +P S TP
Sbjct: 630 PVRRRSRSR-SPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPAR 688
Query: 236 QSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPE---RSGSGSVGNGSSRYSP--SQNSPI 290
+ S S P S SHS +P+ RSGS S SR S S+++
Sbjct: 689 RGRSRSRTPRRGRSRSRSLVRRGRSHS--RTPQRRGRSGSSSERKNKSRTSQRRSRSNSS 746
Query: 291 HHIPSRRSPAKTIAPQNAPRDESRGRSS 318
+ R ++ ++PR +++ R S
Sbjct: 747 PEMKKSRISSRRSRSLSSPRSKAKSRLS 774
Score = 68.2 bits (165), Expect = 3e-11
Identities = 107/389 (27%), Positives = 146/389 (37%), Gaps = 67/389 (17%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRS-RSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
++ R S K R SRSRS R +R R R RS + S+S SR R SR R R
Sbjct: 1756 TSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGS-SQSTSRRRQRSRSRSRVTRRR 1814
Query: 63 RG-------------MRRPYGYRGRGRGYYQGGGGRYHRGGYRPV-WNRRHSRS--PRRG 106
RG R R RGR + R P W R SR+
Sbjct: 1815 RGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHR 1874
Query: 107 RSRSRSP---KRRS------VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRR 157
RSRSR+P +RRS VS +RSRSR+ + R SRS S SR S PV++RR
Sbjct: 1875 RSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRR 1934
Query: 158 GSQEKQT--KKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLS 215
T +++ + +S+S+ P S +S + + + S
Sbjct: 1935 SRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRS 1994
Query: 216 AYDNSP----RSPHSPSPIA-------TPPS-QSSSCSDAPMLSTVHSAKNTP------- 256
SP RS SP+ TPP+ + S S P+L S +P
Sbjct: 1995 RSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRS 2054
Query: 257 -------SQHSHSIQHSP----ERSGSGSVGNGSSRYSP--------SQNSPIHHIPSRR 297
++ S+ SP RS SGS + S +P S+ P+ SR
Sbjct: 2055 RSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRM 2114
Query: 298 SPAKTIAPQNAPRDESRGRSSFYPDGGDQ 326
S + P D R P G +
Sbjct: 2115 SCFSRPSMSPTPLDRCRSPGMLEPLGSSR 2143
Score = 64.3 bits (155), Expect = 5e-10
Identities = 85/337 (25%), Positives = 129/337 (38%), Gaps = 55/337 (16%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRS-------RSRTYSRSRSRDRMYSRD 54
GR + S R + +S + RS S S+K+++RS +S+ R RSR +
Sbjct: 197 GRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPK 256
Query: 55 YRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPK 114
RR +R+ R R R + H+ + GRS S +
Sbjct: 257 SRRAHRSTSADSASSSDTSRSRS--------------RSAAAKTHT-TALAGRSPSPASG 301
Query: 115 RRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPY-----SKSPVSKRRGSQEKQTKKAEG 169
RR S + SP +++ + SSPY K S R S +
Sbjct: 302 RRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGP 361
Query: 170 EPQEESPLKSK---SQEEPKDTFE------HDPSESIDEFNKSSATSGDIWPGLSAYDNS 220
EP +PL ++ +P T + PSE+ ++S S + P S+ ++S
Sbjct: 362 EPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESS 421
Query: 221 PRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSS 280
P PSP T S+ +S S+ S K P+ SH S S + S G
Sbjct: 422 P-----PSPQPTKVSRHAS-------SSPESPKPAPAPGSHREISSSPTSKNRSHGRAKR 469
Query: 281 RYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRS 317
S S H PSRR ++ +P A R SR R+
Sbjct: 470 DKSHS------HTPSRRM-GRSRSPATAKRGRSRSRT 499
Score = 55.5 bits (132), Expect = 2e-07
Identities = 56/160 (35%), Positives = 71/160 (44%), Gaps = 19/160 (11%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKK---RYRSRSRTYSRSRSRDRMYSRDYRRDY 59
RS SR+ ++R +SRS++ +R RS SR R RSRSRT +R R R + R
Sbjct: 1934 RSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTR-- 1991
Query: 60 RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRR-------------HSRSPRRG 106
R +R P R R R R R P RR SRSP
Sbjct: 1992 RRSRSRTSPVTRR-RSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAI 2050
Query: 107 RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSS 146
R RSRS R+ +RS +RS + R + SSS RS S
Sbjct: 2051 RRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRS 2090
Score = 55.5 bits (132), Expect = 2e-07
Identities = 58/210 (27%), Positives = 78/210 (37%), Gaps = 18/210 (8%)
Query: 109 RSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA- 167
RS S S SS S S S S SS S S S SS P KR S K+A
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590
Query: 168 -EGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHS 226
EG P E +P K K + + S S + SS++S S+ +S S S
Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
Query: 227 P------------SPIATPPSQSSSCSDAPMLSTVHSAKNTP----SQHSHSIQHSPERS 270
P SP PP + S S + ++ +++ + S Q SP
Sbjct: 2651 PAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQ 2710
Query: 271 GSGSVGNGSSRYSPSQNSPIHHIPSRRSPA 300
S S GS R + H R +P+
Sbjct: 2711 QSSSSERGSRRGQRGDSRSPSHKRRRETPS 2740
Score = 53.5 bits (127), Expect = 8e-07
Identities = 154/761 (20%), Positives = 264/761 (34%), Gaps = 124/761 (16%)
Query: 96 NRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSK 155
++ HS +P R RSRSP RSR+ ++R + SRSP+ SRS+ + +S +
Sbjct: 470 DKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQ 529
Query: 156 RRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLS 215
RRG PQ +S++ + + S ++S AT G
Sbjct: 530 RRGRSR--------SPQRPGWSRSRNTQRRGRSRSARRGRS---HSRSPATRGRSRSRTP 578
Query: 216 AYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS--- 272
A RS P++ S S P + S TP++ S +P R S
Sbjct: 579 ARRGRSRS--------RTPARRRSRSRTP--TRRRSRSRTPARRGRSRSRTPARRRSRTR 628
Query: 273 GSVGNGSSRYSPSQNS--PIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAK 330
V S SP++ S P+RR +++ P R SR + + A+
Sbjct: 629 SPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPAR 688
Query: 331 TGKFL----KRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKE 386
G+ +R + R ++R + GS R Q S E
Sbjct: 689 RGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPE 748
Query: 387 SGKQKFNDSEGDDTEETEDYRQFRKSVL--------ADQGKSFATASHRNTEEEGLKYKS 438
K + + + R S+ + KS + K KS
Sbjct: 749 MKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKS 808
Query: 439 KVSLKGNRESDGFREEKNYKLK--------------ETGYVVERPSTTKDKHKEEDKNSE 484
+ + +R S ++ K ++G + S T + E+ +
Sbjct: 809 RTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQ 868
Query: 485 RITVKKETQSPE-QVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPL-RIKMIASDSHR 542
R + + + PE + ++ SPP K+ +S R SP ++K I S R
Sbjct: 869 RRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQR 928
Query: 543 PEVKLKMAPVPLDDSNR----------PASLTKDRLL-------ASTLVHSVKKEQEFR- 584
+P P ++R P S + RLL +S+ VK E R
Sbjct: 929 SH-SGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQ 987
Query: 585 ----SIFDHIKL---------------PQASKSTSESFIQHI---VSLVHHVK------E 616
SI + K+ P + + +S +Q +SL VK E
Sbjct: 988 SHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGE 1047
Query: 617 QYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEE 676
YF +++ L + + +H + SPE+ + SPS + +
Sbjct: 1048 SYFGVSSLQLK----GQSQTSPDHRSDTSSPEVRQSHSESPS--------------LQSK 1089
Query: 677 NQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGS--RESSGSRKQEKTPKDYKEYKSY 734
+Q K R S+ ++ R R ++RG+ S +S S +Q + D Y +
Sbjct: 1090 SQTSPKGGRSRSSSPVTELASRSPIR-QDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTV 1148
Query: 735 KDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEF 775
DS Q ++ S + P + S ++++F
Sbjct: 1149 --DSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKF 1187
Score = 52.8 bits (125), Expect = 1e-06
Identities = 97/409 (23%), Positives = 147/409 (35%), Gaps = 61/409 (14%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRS--RSHSRKKRYRSRSRTYSRSRS---------RDRM 50
GR S SS ++S + +SR+ R +++SRT R RS + R+
Sbjct: 1644 GRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARL 1703
Query: 51 YSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPR----RG 106
R R P +R R R R RR + SPR
Sbjct: 1704 SRRSRSASSSPETRSRTPPRHR-RSPSVSSPEPAEKSRSSRR----RRSASSPRTKTTSR 1758
Query: 107 RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSP------------------- 147
R RS SPK R + RSRSR ++ + R RS SS+S+S
Sbjct: 1759 RGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGS 1818
Query: 148 --YSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSA 205
+S+SP + + ++ S +S+S+ P S +S +
Sbjct: 1819 GYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRS 1878
Query: 206 TSGDIWPGLSAYDNSP---RSPHSPSPI--------ATPPSQSSSCSDAPMLSTVHSAKN 254
+ I S SP R S + + A+P S+ S S P ++ S
Sbjct: 1879 RTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSR 1938
Query: 255 TPSQHSHSIQHSP---ERSGSGSVGNGSSRYSPSQNSPI--HHIPSRRSPA--KTIAPQN 307
TP+ S +P R + R S S+ SPI SR SP + +
Sbjct: 1939 TPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRT 1998
Query: 308 APRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDK 356
+P R RS P + ++T ++R SR LL R +R +
Sbjct: 1999 SPVTRRRSRSRTSPVTRRRSRSRTPPAIRR--RSRSRTPLLPRKRSRSR 2045
Score = 52.4 bits (124), Expect = 2e-06
Identities = 102/391 (26%), Positives = 145/391 (37%), Gaps = 55/391 (14%)
Query: 3 RSNSRSHSS-RSKSRSQSSSRSRSRSHSRKKRYRSR-SRTYSRSRSRDRMYSRDYRRDYR 60
RS S S S R S SSS S H K R R SR+ +++ R R RR R
Sbjct: 1635 RSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPR--RRSSR 1692
Query: 61 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRR-SVS 119
++ + R R R R P R S S +SRS +RR S S
Sbjct: 1693 SSPELTRKARLSRRSRS---ASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSAS 1749
Query: 120 SQRSRSRSRRSYRSSRSPRS-SSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 178
S R+++ SRR S PR SRS S K+ ++RR G Q S +
Sbjct: 1750 SPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRR--------DRSGSSQSTSRRR 1801
Query: 179 SKSQEEPKDTFE-------HDPSESIDEFNKSSATSGDIWPGLS----AYDNSPRSPHSP 227
+S+ + T H S + E SS TS G S RS SP
Sbjct: 1802 QRSRSRSRVTRRRRGGSGYHSRSPARQE---SSRTSSRRRRGRSRTPPTSRKRSRSRTSP 1858
Query: 228 SP------IATPPSQSSSCSDAPMLSTVHSAKNTP------SQHSHSIQHSPERSGSGSV 275
+P A+P + S S P++S S T S+ S+ RS + V
Sbjct: 1859 APWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPV 1918
Query: 276 GNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFL 335
S R S S+ P + RRS ++T P R RS P + ++T
Sbjct: 1919 ---SRRRSRSRTPP---VTRRRSRSRT------PTTRRRSRSRTPPVTRRRSRSRTPPVT 1966
Query: 336 KRFTDEESRVFLLDRGNTRDKEASKEKGSEK 366
+R + + R +R ++ + +
Sbjct: 1967 RRRSRSRTSPITRRRSRSRTSPVTRRRSRSR 1997
Score = 48.9 bits (115), Expect = 2e-05
Identities = 92/343 (26%), Positives = 127/343 (37%), Gaps = 55/343 (16%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRY---RSRSRTYSRSRSRDRMYSRDYRRDY 59
RS+ S S S + + S ++S S R+ SR S S S M R
Sbjct: 1377 RSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPS 1436
Query: 60 RNNRGMRRPYGYRGRGRGYYQGGG--GRYHRGGYRPVWNRRHSRSPRRGRSR-SRSPKRR 116
R +R G G G G R+ G P + R+P RGRS SP+ +
Sbjct: 1437 RRSRS--------GSSPGLRDGSGTPSRHSLSGSSPGM-KDIPRTPSRGRSECDSSPEPK 1487
Query: 117 SV-SSQRSRSRSRRSYRSSR---SPRSSSSRSSSPYSKSPVSK-------RRGSQEKQTK 165
++ + R RSRS S + +P+ S S S + V++ R GS ++
Sbjct: 1488 ALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV 1547
Query: 166 KAEGEPQEESPLKSKSQEEPKDTF---EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPR 222
K PQE S S + K + S S E + S S P S +SP
Sbjct: 1548 KPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLS----PRRSRSGSSPE 1603
Query: 223 SPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNG---S 279
P A P +QS S S +P + + + P RS SGS G S
Sbjct: 1604 VKDKPR--AAPRAQSGSDS-------------SPEPKAPAPRALPRRSRSGSSSKGRGPS 1648
Query: 280 SRYSPSQNSPIHHIP----SRRSPAKTIAPQNAPRDESRGRSS 318
S S S H P +RR + P+ R R RSS
Sbjct: 1649 PEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSS 1691
Score = 48.9 bits (115), Expect = 2e-05
Identities = 62/231 (26%), Positives = 92/231 (39%), Gaps = 23/231 (9%)
Query: 93 PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 152
P + + SPR S R+ R+RSR + R +S R+ SP
Sbjct: 2373 PALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSP----- 2427
Query: 153 VSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPK----DTFEHDPSESIDEFNKSSATS- 207
S R G Q+ + Q SP+ S ++ + T S+S+ ++ TS
Sbjct: 2428 -SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSS 2486
Query: 208 -GDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHS 266
GD LS +P PH S + PP+ S+ L+ + AK S S S S
Sbjct: 2487 AGDHNGMLSV--PAPGVPH--SDVGEPPA-STGAQQPSALAALQPAKERRSSSSSSSSSS 2541
Query: 267 PERSGSGSVGNGSSRYSPSQNSPIHHIP------SRRSPAKTIAPQNAPRD 311
S S S + SS S S +S +P +R P+ T AP+ A R+
Sbjct: 2542 SSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVRE 2592
Score = 48.9 bits (115), Expect = 2e-05
Identities = 57/214 (26%), Positives = 82/214 (38%), Gaps = 16/214 (7%)
Query: 113 PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEP- 171
P + + Q S + + + RS SSSS SSS S S S S + +EG
Sbjct: 2509 PPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSL 2568
Query: 172 --QEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSP 229
Q E LK P P E++ E T S+ +S S S S
Sbjct: 2569 PVQPEVALKRVPSPTPA------PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSS 2622
Query: 230 IATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSP 289
++ S SSS S + S+ S+ ++PS Q P+ + G R S S P
Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERR-SRSPRKP 2681
Query: 290 IHHIPSRRS------PAKTIAPQNAPRDESRGRS 317
I + RS + +PQ +PRD+ S
Sbjct: 2682 IDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSS 2715
Score = 48.9 bits (115), Expect = 2e-05
Identities = 50/166 (30%), Positives = 61/166 (36%), Gaps = 23/166 (13%)
Query: 102 SPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQE 161
+P + + RS S S SS S S S S SS S SSSS SSS S SP + G Q
Sbjct: 2599 TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ- 2657
Query: 162 KQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP 221
P+ SP K P + P + ID S + S SP
Sbjct: 2658 -------ALPKPASPKK----PPPGERRSRSPRKPIDSLRDSRSLS-----------YSP 2695
Query: 222 RSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSP 267
PSP +P Q SS S+ +PS SP
Sbjct: 2696 VERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSP 2741
Score = 48.1 bits (113), Expect = 3e-05
Identities = 63/238 (26%), Positives = 89/238 (37%), Gaps = 46/238 (19%)
Query: 132 RSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEH 191
RSS S SSSS SSS S S S GS ++ + Q E LK P
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA----- 2585
Query: 192 DPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHS 251
P E++ E P P+P SSS S
Sbjct: 2586 -PKEAVREGR----------------------PPEPTPAKRKRRSSSSSSS--------- 2613
Query: 252 AKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRD 311
++ S S S S S S S + SS S S +SP P ++ K +P+ P
Sbjct: 2614 --SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPG 2671
Query: 312 ESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKE-ASKEKGSEKGR 368
E R RS P ++ + + L E R + + RD++ +S E+GS +G+
Sbjct: 2672 ERRSRSPRKP----IDSLRDSRSLSYSPVERRRP--SPQPSPRDQQSSSSERGSRRGQ 2723
Score = 47.8 bits (112), Expect = 4e-05
Identities = 88/383 (22%), Positives = 135/383 (35%), Gaps = 49/383 (12%)
Query: 6 SRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGM 65
S S RS+S S S++++R+ R+ RSRS + S+ R+ R R+ G
Sbjct: 1550 SASPQERSESDSSPDSKAKTRTPLRQ---RSRSGSSPEVDSKSRLSPR------RSRSGS 1600
Query: 66 RRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSR---SPKRRSVSSQR 122
+ R Q G + +PR RSR S K R S +
Sbjct: 1601 SPEVKDKPRAAPRAQSGSDSSPEP---------KAPAPRALPRRSRSGSSSKGRGPSPEG 1651
Query: 123 SRS---------RSRRSYRSSRSPRSSSSRSSSPYSK-----SPVSKRRGSQEKQTKKAE 168
S S +SR + R SRS ++S +P + SP R+ ++++ A
Sbjct: 1652 SSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSAS 1711
Query: 169 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 228
P+ S + + P + +S + SA+S P RSP SP
Sbjct: 1712 SSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASS----PRTKTTSRRGRSP-SPK 1766
Query: 229 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNS 288
P S+S S + + + S Q S RS G S Y S
Sbjct: 1767 PRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGY--HSRS 1824
Query: 289 PIHHIPSRRSPAKTIAPQNAP---RDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRV 345
P SR S + P R SR R+S P + A + SR
Sbjct: 1825 PARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRR----SRSRT 1880
Query: 346 FLLDRGNTRDKEASKEKGSEKGR 368
L+ R +R + + + + R
Sbjct: 1881 PLISRRRSRSRTSPVSRRRSRSR 1903
Score = 45.8 bits (107), Expect = 2e-04
Identities = 120/601 (19%), Positives = 201/601 (33%), Gaps = 114/601 (18%)
Query: 294 PSRRSPAKTIAPQNAPRDESR--------GRSSFYPDGGDQETAKTGKFLKRFTDEESRV 345
P +R PA T Q A +E + G S Y DG + + + K+ E +
Sbjct: 112 PGQR-PAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKP 170
Query: 346 FLLDRGNTRD-----KEASKEKGSEKGRAEGEW-------EDQEALDYFSDKESGKQKFN 393
+ L R ++ K+ K+K ++GR + + + S+ ES K+K
Sbjct: 171 YSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHR 230
Query: 394 DSEGDDTEETEDYRQFR--------------KSVLADQGKSFATASHRNTEEEGLKYKSK 439
+++D ++ R +S AD S T+ R+ + +
Sbjct: 231 SPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTA 290
Query: 440 VSLKGNRESDGFREEKNYKLKETGYV-VERPSTTKDKHKEEDKNSERITVKKETQSPEQV 498
++ + + G R E + E G +RPS+ + T K+ SP +
Sbjct: 291 LAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPE-------------TATKQPSSPYED 337
Query: 499 KSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSN 558
K + K+ P + E+S+ E P ++A L P+ + N
Sbjct: 338 KDKDKKEKSATRPS-----PSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN 392
Query: 559 RP--ASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKE 616
P AS T+DR S K E KLPQ+S S S + H
Sbjct: 393 PPSEASPTRDR--------SPPKSPE--------KLPQSSSSESSPPSPQPTKVSRHASS 436
Query: 617 QYFK-------------SAAMTLNERFTSYQKATEEHST-------RQKSPEIHRR--ID 654
S++ T R K + HS R +SP +R
Sbjct: 437 SPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSR 496
Query: 655 ISPSTLRKHTRLAGEE-----------RVFKEENQKGDKKLRCDSADLRHDIDRRRKERS 703
T R H+R + R + + + + + RR + RS
Sbjct: 497 SRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRS 556
Query: 704 KERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSRE 763
RG S ++ R + +TP +S + R + +R S S +P+ R
Sbjct: 557 ARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRS---RTPARRG 613
Query: 764 EKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRG 823
S+ +T ++ S +R G A+RGR R RG
Sbjct: 614 RSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTP------ARRGRSRSRTPARRG 667
Query: 824 R 824
R
Sbjct: 668 R 668
Score = 45.1 bits (105), Expect = 3e-04
Identities = 59/245 (24%), Positives = 97/245 (39%), Gaps = 32/245 (13%)
Query: 105 RGRSRSRSPKRRSVSSQRSRSRSRRSYRSS-RSPRSSSSRSSSPYSKSPVSKR--RGSQE 161
R S SRSP + ++ + R RRS SS R R SS+ S+S KR R
Sbjct: 175 RESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTP 234
Query: 162 KQTKKAEGEPQEESPLKS---KSQEEPKDTFEHDPSESIDEFNKS----SATSGDIWPGL 214
K +K++ + ++ S + KS+ + T S S ++S + T G
Sbjct: 235 KSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGR 294
Query: 215 SAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSA-------KNTPSQHSHSIQHSP 267
S S R +P + P + S+ +P +T + K+ + + SP
Sbjct: 295 SPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSP 354
Query: 268 ERSGSG----------SVGNGSS----RYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDES 313
ERS +G + +G S +P P++ PS SP + +P +P
Sbjct: 355 ERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNP-PSEASPTRDRSPPKSPEKLP 413
Query: 314 RGRSS 318
+ SS
Sbjct: 414 QSSSS 418
Score = 42.7 bits (99), Expect = 0.001
Identities = 161/801 (20%), Positives = 259/801 (32%), Gaps = 152/801 (18%)
Query: 107 RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPY----SKSPVSKRRGSQEK 162
RS + SP+ R S+ +S+ S SP+ SRSSSP S+SP+ + RG
Sbjct: 1068 RSDTSSPEVRQSHSESPSLQSK----SQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSA 1123
Query: 163 QTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGD---IWPGLSAYDN 219
G E+S +S S P D + + + +A S + + P A +
Sbjct: 1124 SPMLKSGMSPEQSRFQSDSSSYP----TVDSNSLLGQSRLETAESKEKMALPPQEDATAS 1179
Query: 220 SPRSPHSPSP----------------IATPPSQSSSCSDAPMLSTVHSAKNTPSQH---- 259
PR SP + TPP + S +P +SA T SQ
Sbjct: 1180 PPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELM 1239
Query: 260 --------------SHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAP 305
SH E S S + P+ + + S+ S P
Sbjct: 1240 EVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVP 1299
Query: 306 ------------------QNAP-RDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVF 346
N+P R+ S G + + G T F ++ + F
Sbjct: 1300 SMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPF 1359
Query: 347 L----------LDRGNTR-----DKEASKEKGSEKGRAEGEWEDQEALDYF---SDKESG 388
L + +TR E S + + G + + LD +E
Sbjct: 1360 LNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERS 1419
Query: 389 KQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHR-NTEEEGLKYKSKVSLKGNRE 447
+ D T R S + S + H + G+K + +G E
Sbjct: 1420 SSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSE 1479
Query: 448 SDGFREEKNYKLKETGYVVER-PSTTKDKHK----EEDKNSERITVKKET-------QSP 495
D E K L +T R PS+ + +K + +++ +V ++T Q
Sbjct: 1480 CDSSPEPK--ALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRS 1537
Query: 496 EQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLD 555
S++L SP D+ S + +PLR + + S PEV K P
Sbjct: 1538 RSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSS--PEVDSKSRLSPRR 1595
Query: 556 DSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS---------ESFIQH 606
+ + KD+ A+ S LP+ S+S S E
Sbjct: 1596 SRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSST 1655
Query: 607 IVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDIS---------- 656
S H K + + + + E T + S+R SPE+ R+ +S
Sbjct: 1656 ESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSR-SSPELTRKARLSRRSRSASSSP 1714
Query: 657 ---PSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDR---------------- 697
T +H R E + ++ R S+ R
Sbjct: 1715 ETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSR 1774
Query: 698 ----RRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKR---EQDHSRSS 750
R K R+ R D GS +S+ R+Q + + H R Q+ SR+S
Sbjct: 1775 SRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTS 1834
Query: 751 S---SSASPSSPSSREEKESK 768
S S + P+SR+ S+
Sbjct: 1835 SRRRRGRSRTPPTSRKRSRSR 1855
Score = 42.7 bits (99), Expect = 0.001
Identities = 49/153 (32%), Positives = 60/153 (39%), Gaps = 22/153 (14%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDY---- 59
S+S S SS S S S SSS S S S S S S + S S S + + +
Sbjct: 2608 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKK 2667
Query: 60 -----RNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPK 114
R +R R+P R Y PV RR S P +S S +
Sbjct: 2668 PPPGERRSRSPRKPIDSLRDSRSL-----------SYSPVERRRPSPQPSPRDQQSSSSE 2716
Query: 115 RRSVSSQR--SRSRSRRSYRSSRSPRSSSSRSS 145
R S QR SRS S + R + SPR RSS
Sbjct: 2717 RGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSS 2749
Score = 41.6 bits (96), Expect = 0.003
Identities = 136/685 (19%), Positives = 234/685 (34%), Gaps = 87/685 (12%)
Query: 114 KRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQE 173
+R +VS +S+S+ S + P +SS +S + + + E +
Sbjct: 1276 ERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRN 1335
Query: 174 ESPLKSK-----SQEEPKDT-------FEHDPSESIDEFNKSSA--TSGDIWP------G 213
PL ++ S E +D E DPS + E + S+ +S ++ P G
Sbjct: 1336 SGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAG 1395
Query: 214 LSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSG 273
+S+ + S SP + TP + SS + +P + TPS+ S S R GSG
Sbjct: 1396 MSS-NQSISSPVLDAVPRTPSRERSSSASSPEMKD--GLPRTPSRRSRSGSSPGLRDGSG 1452
Query: 274 SVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGK 333
+ SR+S S +SP ++ PR SRGRS + +++ K
Sbjct: 1453 T----PSRHSLSGSSP--------------GMKDIPRTPSRGRS-------ECDSSPEPK 1487
Query: 334 FLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFN 393
L + SR N + +E+ + + + + L S S ++
Sbjct: 1488 ALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV 1547
Query: 394 DSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFRE 453
E +E S + K+ R+ + SK L R G
Sbjct: 1548 KPSASPQERSES-----DSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSP 1602
Query: 454 EKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPL 513
E +K+ R + D E + R + + ++S K P
Sbjct: 1603 E----VKDKPRAAPRAQSGSDSSPEPKAPAPR-ALPRRSRSGSSSKGRG---------PS 1648
Query: 514 HKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTL 573
+ + E S + + S P+ K + P + P K RL +
Sbjct: 1649 PEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSR 1708
Query: 574 VHSVKKEQEFRSIFDHIKLPQAS------KSTSESFIQHIVSLVHHVKEQYFKSAAMTLN 627
S E R+ H + P S KS S + S + +S +
Sbjct: 1709 SASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPR 1768
Query: 628 --ERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLR 685
+R S + + +TR++ R S ST R+ R RV + R
Sbjct: 1769 GLQRSRSRSRREKTRTTRRRD-----RSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSR 1823
Query: 686 CDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQD 745
+ + R + RG S+ S + +P +K +S + H+R +
Sbjct: 1824 SPARQ-----ESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRS 1878
Query: 746 HSR--SSSSSASPSSPSSREEKESK 768
+ S S S +SP SR S+
Sbjct: 1879 RTPLISRRRSRSRTSPVSRRRSRSR 1903
Score = 39.3 bits (90), Expect = 0.016
Identities = 52/263 (19%), Positives = 89/263 (33%), Gaps = 21/263 (7%)
Query: 83 GGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSS 142
GG+ G RP H + + R +S S R +R + +
Sbjct: 106 GGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAP 165
Query: 143 RSSSPY--------SKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPS 194
PY S+SP K++ +K+ KK G E S + + ++ K S
Sbjct: 166 EPPKPYSLVRESSSSRSPTPKQK---KKKKKKDRGRRSESSSPRRERKKSSKKKKHRSES 222
Query: 195 ESIDEFNKSSATSGDIWPGLSAYDNSPRSPHS--PSPIATPPSQSSSCSDAPMLSTVHSA 252
ES ++S + D + S P+P + +S+S A T S
Sbjct: 223 ESKKRKHRSPTPKSK----RKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSR 278
Query: 253 KNTPSQHSHSIQ---HSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAP 309
+ + +H+ SP SG G G + +S + S + K +
Sbjct: 279 SRSAAAKTHTTALAGRSPS-PASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYED 337
Query: 310 RDESRGRSSFYPDGGDQETAKTG 332
+D+ + S E + TG
Sbjct: 338 KDKDKKEKSATRPSPSPERSSTG 360
Score = 38.5 bits (88), Expect = 0.027
Identities = 49/188 (26%), Positives = 64/188 (34%), Gaps = 46/188 (24%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
RS+S S SS S S S SSS S S S S S S + S S
Sbjct: 2606 RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA------------- 2652
Query: 63 RGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQR 122
+ G + + + P G RSRSP++ S +
Sbjct: 2653 -------------------------KPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRD 2687
Query: 123 SRSRS-----RRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL 177
SRS S RR SPR S SS S+ +RG + K E P+
Sbjct: 2688 SRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRG---QRGDSRSPSHKRRRETPSPRPM 2744
Query: 178 KSKSQEEP 185
+ +S P
Sbjct: 2745 RHRSSRSP 2752
Score = 35.4 bits (80), Expect = 0.23
Identities = 35/144 (24%), Positives = 54/144 (37%), Gaps = 27/144 (18%)
Query: 704 KERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSS----------- 752
K R +GSR S + + +TP + +S + ++ R SRS+SS
Sbjct: 1664 KSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPR 1723
Query: 753 ---SASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWA 809
S S SSP E+ S + R + G + +PRG
Sbjct: 1724 HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRG-------------L 1770
Query: 810 KRGRGRGTFQRGRGRFNFKKSGSS 833
+R R R ++ R +SGSS
Sbjct: 1771 QRSRSRSRREKTRTTRRRDRSGSS 1794
Score = 34.3 bits (77), Expect = 0.51
Identities = 39/179 (21%), Positives = 69/179 (38%), Gaps = 27/179 (15%)
Query: 697 RRRKERSKERGDSKGS------RESSGSRKQEKTPKDYKEYKSYKDDSKHKRE-QDHSRS 749
+++K++ K+RG S R+ S +K+ ++ + K+ K K KR+ +D R
Sbjct: 187 QKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRK 246
Query: 750 SSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWA 809
S S +P+ S R + + + T SR R + A
Sbjct: 247 RSRSTTPAPKSRRAHRSTSADSASSSDTSR-----------SRSRSAAAKTHTTAL---A 292
Query: 810 KRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEK 868
R + +RG G F + G++ Q E + + E KD+ K+EK
Sbjct: 293 GRSPSPASGRRGEGDAPFSEPGTT------STQRPSSPETATKQPSSPYEDKDKDKKEK 345
Score = 32.7 bits (73), Expect = 1.5
Identities = 36/164 (21%), Positives = 65/164 (39%), Gaps = 15/164 (9%)
Query: 620 KSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQK 679
+S + T R S + +R +SP + RR S R R +G R + ++
Sbjct: 603 RSRSRTPARRGRSRSRTPARRRSRTRSP-VRRR-----SRSRSPARRSGRSRS-RTPARR 655
Query: 680 GDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSK 739
G + R + R R + ++ G S+ + R + +TP+ + + S
Sbjct: 656 GRSRSRTPARRGRS----RSRTPARRSGRSRSRTPARRGRSRSRTPRRGRS----RSRSL 707
Query: 740 HKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKE 783
+R + HSR+ S S R+ K +R + EMK+
Sbjct: 708 VRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKK 751
Score = 30.0 bits (66), Expect = 9.7
Identities = 19/49 (38%), Positives = 20/49 (40%)
Query: 719 RKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES 767
R E TP K S S S SSSSS+S SS SS S
Sbjct: 2594 RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
>gi|115511057 hypothetical protein LOC256643 [Homo sapiens]
Length = 682
Score = 104 bits (260), Expect = 3e-22
Identities = 110/448 (24%), Positives = 193/448 (43%), Gaps = 55/448 (12%)
Query: 324 GDQETAKTGKFLKRFTDEESRVFLLDRGNT--RDKEASKEKGSEKGRAEGEWEDQEALDY 381
G ++ F KR+ ++ G+T R K+ + + E R +W+ + +L
Sbjct: 191 GSEDFETRSSFQKRYPEDRD---FRKYGHTSKRPKDVERYESREPAR-NPKWKPEHSLPP 246
Query: 382 FSDKES----GKQKFNDSEGDDTEETE------DYRQFRKSVLADQGKSFATA-SHRNTE 430
+ + G Q + +E + E + DYR R +L D + F+ + + +
Sbjct: 247 YQEDTDQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLL-DGDQDFSDGRTQKYCK 305
Query: 431 EEGLKYKSKVSLKG--NRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITV 488
EE KY + KG NRE D F + + ++ K+ K K+S T
Sbjct: 306 EEDRKYSFQ---KGPLNRELDCFNTGRGRETQD--------GQVKEPFKPSKKDSIACTY 354
Query: 489 KKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLK 548
+ + ++K K+ K ++ + + +K + + + +K
Sbjct: 355 SNKNDVDLRSSNDKWKEKIKKEGDCRKESNSSSNQLDKSQKLPDVKPSPINLRKKSLTVK 414
Query: 549 MAPVPLDDSNRPAS-LTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQ--ASKSTSESFIQ 605
+ D+ R AS + +R ++ LV +K + F +F+H+ Q +K T E F Q
Sbjct: 415 VDVKKTVDTFRVASSYSTERQMSHDLVAVGRKSENFHPVFEHLDSTQNTENKPTGE-FAQ 473
Query: 606 HIVSLVHHVKEQYFKSAAMTLNERFTSYQ---KATEEHSTRQKSPEIHRRIDISPSTLRK 662
I++++H VK YF S +TL+ERF++ Q KA PEIHRRID+S + L+
Sbjct: 474 EIITIIHQVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSDPEIHRRIDMSLAELQ- 532
Query: 663 HTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGD---------SKGSR 713
++ V E Q K + D DLRHDI+RRRKER + + + +
Sbjct: 533 -----SKQAVIYESEQTLIKII--DPNDLRHDIERRRKERLQNEDEHIFHIASAAERDDQ 585
Query: 714 ESSGSRKQEKTPKDYKEYKSYKDDSKHK 741
SS S+ KD +K ++ + H+
Sbjct: 586 NSSFSKNYTTQRKDIITHKPFEVEGNHR 613
Score = 36.6 bits (83), Expect = 0.10
Identities = 107/566 (18%), Positives = 196/566 (34%), Gaps = 91/566 (16%)
Query: 13 SKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYR 72
S+ QS R SR + + Y RS + + S + +Y M +P+
Sbjct: 53 SEKHGQSKPRIPSRGNIYYQSYEHRSPSPNIRNSLENVY-------------MYKPH--- 96
Query: 73 GRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYR 132
RGY G G R Y P ++ P + R+ P++ R R S +
Sbjct: 97 ---RGYSPGRGDSNRRAQYMPKYS---EGIPYKEHERNSYPQKVQGGHSPDDHRVRGSGK 150
Query: 133 SSRSPRSS---SSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTF 189
+ P+ S S R + + + +R +EK ++ ++ S + P+D
Sbjct: 151 GGKPPQRSIADSFRFEGKWHEDELRHQRIQEEKYSQSTRRGSEDFETRSSFQKRYPED-- 208
Query: 190 EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTV 249
++ +S D+ Y++ R P A P S P
Sbjct: 209 -----RDFRKYGHTSKRPKDV----ERYES--REP------ARNPKWKPEHSLPPYQEDT 251
Query: 250 HSAKNTPSQHSHSIQHSPERSGSGSVG-----------NGSSRYSPSQNSPIHHIPSRRS 298
P + H+ + PE S + V +G +S + R+
Sbjct: 252 DQWNLGPQTYRHAEREHPETSSATKVSYDYRHKRPKLLDGDQDFSDGRTQKYCKEEDRKY 311
Query: 299 PAKTIAPQNAPRD-ESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKE 357
+ P N D + GR DG +E K K ++S N D
Sbjct: 312 SFQK-GPLNRELDCFNTGRGRETQDGQVKEPFKPSK-------KDSIACTYSNKNDVDLR 363
Query: 358 ASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQ 417
+S +K EK + EG+ + S+ S + + D + R+ +V D
Sbjct: 364 SSNDKWKEKIKKEGDCRKE------SNSSSNQLDKSQKLPDVKPSPINLRKKSLTVKVDV 417
Query: 418 GK---SFATASHRNTEEEGLKYKSKVSLKGNRESDGFR-------EEKNYKLKETGYVVE 467
K +F AS +TE + S + R+S+ F +N + K TG +
Sbjct: 418 KKTVDTFRVASSYSTERQ----MSHDLVAVGRKSENFHPVFEHLDSTQNTENKPTGEFAQ 473
Query: 468 RPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDL-FDYSPPLHKNLD------AR 520
T + K S IT+ + + + + + ++ + P +H+ +D
Sbjct: 474 EIITIIHQVKANYFPSPGITLHERFSTMQDIHKADVNEIPLNSDPEIHRRIDMSLAELQS 533
Query: 521 EKSTFREESPLRIKMIASDSHRPEVK 546
+++ E IK+I + R +++
Sbjct: 534 KQAVIYESEQTLIKIIDPNDLRHDIE 559
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 98.2 bits (243), Expect = 3e-20
Identities = 99/346 (28%), Positives = 137/346 (39%), Gaps = 64/346 (18%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHS-RKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR 60
G S+ R S RS+S S + R SRS S K R RSRSR+ ++R R R S + RD
Sbjct: 379 GSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCS 438
Query: 61 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPR--RGRSRSRSPKRRSV 118
+R PY R R R + R SRSP R RSRSRSP +
Sbjct: 439 RSRS---PYKARDRSRSRSPNKARDHSR-----------SRSPNKARDRSRSRSPSKERD 484
Query: 119 SSQRSRSRSRRSYRSSRSP---------RSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG 169
SQ R +R SRSP RSSS S+SP +R+ Q + K
Sbjct: 485 HSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERD 544
Query: 170 EPQEESP--------LKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP 221
Q SP +S S+E + + E ++SS+ D +
Sbjct: 545 RSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERD--------HSRS 596
Query: 222 RSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSR 281
RSP+ S + P + S + +HS +P + G+ S SS+
Sbjct: 597 RSPNKQSGYSRPRASS-------------------KEKAHSRSRTPSKEGNHSQSRTSSK 637
Query: 282 YSPSQNSPIHHIPS-RRSPAKT--IAPQNAPRDESRGRSSFYPDGG 324
S S + P +RSP +T ++ P S S +P GG
Sbjct: 638 ESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGG 683
Score = 90.5 bits (223), Expect = 6e-18
Identities = 109/441 (24%), Positives = 169/441 (38%), Gaps = 53/441 (12%)
Query: 10 SSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDY-----RNNRG 64
SSR KS +Q+S+RSR +SHS+ + R RSR+ S+ R+ R+ S ++R++ R +G
Sbjct: 263 SSRVKSYNQASTRSRPQSHSQSRSPR-RSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKG 321
Query: 65 MRRPYGYRGRGRGYYQGGG---GRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 121
+ G + R + +G R R G W+R S+ SRS S +R S
Sbjct: 322 ILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSS 381
Query: 122 RSRSRSRRSYRSSRSPRSSSSRSSSP-------YSKSPVSKRRGSQEKQTKKAEGEPQEE 174
R S RS S + + SRS SP S+SP R S+ + KA +
Sbjct: 382 SPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSR 441
Query: 175 SPLKSKSQ---EEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIA 231
SP K++ + P +H S S ++ S + SP S +
Sbjct: 442 SPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRS------------RSPSKERDHSQLG 489
Query: 232 TPPSQ------SSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPS 285
+P + S + + S+K + S S +R S S R
Sbjct: 490 SPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSR 549
Query: 286 QNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRV 345
S RSP+K RD R RS ++E ++ + SR
Sbjct: 550 SPSEEREHRQSRSPSK-------ERDRRRWRS----PSKERERRQSRSSSEERDHSRSRS 598
Query: 346 FLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETED 405
G +R + +SKEK + R + E + S KES + D + +
Sbjct: 599 PNKQSGYSRPRASSKEKAHSRSRTPSK-EGNHSQSRTSSKESDPSQSTVPRSPDWKRSPT 657
Query: 406 YRQFRKSVLADQGKSFATASH 426
R S L+ T+SH
Sbjct: 658 ----RTSSLSQNRTPSKTSSH 674
Score = 77.4 bits (189), Expect = 5e-14
Identities = 167/776 (21%), Positives = 264/776 (34%), Gaps = 142/776 (18%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
R++ S SS ++S S+ R+ S S + R RS++RT SR + R D R +
Sbjct: 53 RNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCH 112
Query: 63 RGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQR 122
+ RR RGR G RR SRS +R SR+ +P R
Sbjct: 113 Q--RRGTHSRGRTPG-------------------RRGSRSSKRSPSRASTPGR------- 144
Query: 123 SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQ 182
R+ + +SR +P S+ S+ + +T E + L KS
Sbjct: 145 --------IRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSY 196
Query: 183 EEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATP-----PSQS 237
P + SE + + + P DN SP S + + PS+
Sbjct: 197 RPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNP--SPSSSRKVKSYGQMIIPSRE 254
Query: 238 SSCSDAPMLSTVHS---AKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIP 294
S S M S V S A SHS SP RS SGS SR S + +H
Sbjct: 255 KSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVR-SHSWKRNHSR 313
Query: 295 SRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTR 354
+R K I Q +SR S GK + +SR R +
Sbjct: 314 ARSRTRKGILSQMGRHSQSRSHSK-------------GK-----SQNQSRTPRRGRSHNW 355
Query: 355 DKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVL 414
+ SKE+ R+ + D KESG+ + G ++ + R +
Sbjct: 356 SRNPSKERSHSHSRSSSKERDHRGSSS-PRKESGRSQ----SGSPNKQRDHSRSRSPNKA 410
Query: 415 ADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKD 474
D+ +S + R+ S N+ D R YK ++ S ++
Sbjct: 411 RDRSRSRSPYKARDRSR---------SRSPNKARDCSRSRSPYKARDR-------SRSRS 454
Query: 475 KHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIK 534
+K D + R K +S + S++ +D P ++E+ R SP + +
Sbjct: 455 PNKARDHSRSRSPNKARDRSRSRSPSKE-RDHSQLGSP------SKERDHRRSRSPSKER 507
Query: 535 MIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQ 594
+ + D R S +K+R + S KE++
Sbjct: 508 QCRQSRSSSKER---------DHRRSRSPSKERQRRQS--RSPNKERD------------ 544
Query: 595 ASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRID 654
S+S S S +E+ + + ER + R S E RR
Sbjct: 545 RSQSRSPS------------EEREHRQSRSPSKER--------DRRRWRSPSKERERRQS 584
Query: 655 ISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRE 714
S S R H+R + Q G + R S + H R + S+E
Sbjct: 585 RSSSEERDHSRSRSPNK------QSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKE 638
Query: 715 SSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKE 770
S S+ D+K + R + S S S PS + + +S+ +
Sbjct: 639 SDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQAD 694
Score = 53.5 bits (127), Expect = 8e-07
Identities = 141/673 (20%), Positives = 242/673 (35%), Gaps = 78/673 (11%)
Query: 139 SSSSRSSSP-YSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESI 197
SS RSS P S +P + + + + + +P +S +P + S S
Sbjct: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61
Query: 198 DEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS 257
+ KS++T A N P S A PS+ S+ + S +
Sbjct: 62 SKSTKSTSTK-------RAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQR 114
Query: 258 QHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRS 317
+ +HS +P R GS S SR S H +R A + + + SRG+S
Sbjct: 115 RGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHG--ARPGMASRVRTPTSQQKGSRGKS 172
Query: 318 SFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQE 377
P ++E + + R ++S G R E + + K + +E
Sbjct: 173 YGRPRTSNRERSDSQP---RNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKE 229
Query: 378 ALDYFSDKESGKQKF--------NDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNT 429
D S S K K + TE + + + ++ + +S + +
Sbjct: 230 KSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRR 289
Query: 430 EEEGLKYK--SKV---SLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSE 484
G + + S+V S K N R K L + G + S +K K + + +
Sbjct: 290 SRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGI-LSQMGRHSQSRSHSKGKSQNQSRTPR 348
Query: 485 RITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPE 544
R +++P + +S +S K D R S+ R+ES S + + +
Sbjct: 349 RGRSHNWSRNPSKERSHS------HSRSSSKERDHRGSSSPRKESGR--SQSGSPNKQRD 400
Query: 545 VKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFI 604
+P D +R S K R + + S K ++ K S+S S +
Sbjct: 401 HSRSRSPNKARDRSRSRSPYKARDRSRS--RSPNKARDCSRSRSPYKARDRSRSRSPNKA 458
Query: 605 QHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHT 664
+ + R S KA + +R S E SPS R H
Sbjct: 459 RD--------------------HSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHR 498
Query: 665 RLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKG-SRESSGSRKQEK 723
R + ++ ++ R S + H RR + SKER + S R Q +
Sbjct: 499 RSRSPSK------ERQCRQSRSSSKERDH---RRSRSPSKERQRRQSRSPNKERDRSQSR 549
Query: 724 TPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKE 783
+P + +E++ + SK E+D R S S RE ++S+ EE + H +
Sbjct: 550 SPSEEREHRQSRSPSK---ERDRRRWRSPS------KERERRQSRSSSEE--RDHSRSRS 598
Query: 784 YSGFAGVSRPRGT 796
+ +G SRPR +
Sbjct: 599 PNKQSGYSRPRAS 611
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 90.5 bits (223), Expect = 6e-18
Identities = 98/286 (34%), Positives = 132/286 (46%), Gaps = 32/286 (11%)
Query: 4 SNSRSHS-SRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRD---- 58
S SRS S S S+SRS+S SRS+SRS S+K++ RS S+ SRSRS SR +D
Sbjct: 216 SKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEE 275
Query: 59 -YRNNRGMRRPYG-------------YRGRGRGYYQGGGGRYHRG-GYRPVWNRRHSRSP 103
+NN + +P R + R + G RG + SRS
Sbjct: 276 KIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSR 335
Query: 104 RRGRSRSRSPKR-RSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEK 162
+G SRSRS R +S ++ R RSR RS RS S RS SK + GS +K
Sbjct: 336 SKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKR--DSKAGSSKK 393
Query: 163 QTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESID-EFNKSSATSGDIWPGLS-AYDNS 220
+ K+ Q SP +S S+E EH SES E S +G S + NS
Sbjct: 394 KKKEDTDRSQSRSPSRSVSKER-----EHAKSESSQREGRGESENAGTNQETRSRSRSNS 448
Query: 221 PRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHS 266
P+ PS + S+S+S + + S SA +PS+ S S HS
Sbjct: 449 KSKPNLPSE-SRSRSKSASKTRSRSKSRSRSASRSPSR-SRSRSHS 492
Score = 76.6 bits (187), Expect = 9e-14
Identities = 85/319 (26%), Positives = 127/319 (39%), Gaps = 47/319 (14%)
Query: 29 SRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHR 88
SR++R SRSR++SRSRSR R + R R+ G + + R R R
Sbjct: 179 SRRRRSYSRSRSHSRSRSRSR-----HSRKSRSRSGSSKSSHSKSRSRS----------R 223
Query: 89 GGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRS-SRS----------- 136
G R +R SRS + RSRS+ K RS S ++SRSRS + +S S+S
Sbjct: 224 SGSR---SRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNN 280
Query: 137 -------PRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTF 189
RS S S S+S +RR +EK+ + G QE+S +S+S+ K
Sbjct: 281 DNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGS 340
Query: 190 EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTV 249
+K S + +S S + S++ S T
Sbjct: 341 RSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTD 400
Query: 250 HSAKNTPS-----QHSHSIQHSPERSGSGSVGNGSSRY-----SPSQNSPIHHIPSRRSP 299
S +PS + H+ S +R G G N + S S + ++PS
Sbjct: 401 RSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRS 460
Query: 300 AKTIAPQNAPRDESRGRSS 318
A + R +SR RS+
Sbjct: 461 RSKSASKTRSRSKSRSRSA 479
Score = 67.8 bits (164), Expect = 4e-11
Identities = 76/286 (26%), Positives = 110/286 (38%), Gaps = 23/286 (8%)
Query: 99 HSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRG 158
+ R R + S +RRS S RS SRSR R SR RS S S S +SKS R G
Sbjct: 166 NGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSG 225
Query: 159 SQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYD 218
S+ + K+ Q S K + P S S KS + S D A +
Sbjct: 226 SRSR--SKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSA---GKSRSKSKD-----QAEE 275
Query: 219 NSPRSPHSPSPIATPPSQSSSCSDAPMLS---TVHSAKNTPSQHSHSIQHSPERSGSGSV 275
+ + P + PS+ S S + S V K S + S +S S S
Sbjct: 276 KIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSR 335
Query: 276 GNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFL 335
G SR S++ +R K ++ R SR +S G + +K G
Sbjct: 336 SKGGSR---SRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSK 392
Query: 336 KRFTDEESRVFLLDRGNTRDKEASKEK---GSEKGRAEGEWEDQEA 378
K+ ++ R + + + SKE+ SE + EG E + A
Sbjct: 393 KKKKEDTDR----SQSRSPSRSVSKEREHAKSESSQREGRGESENA 434
Score = 65.5 bits (158), Expect = 2e-10
Identities = 73/224 (32%), Positives = 96/224 (42%), Gaps = 51/224 (22%)
Query: 1 MGRSNSRS---HSSRSKSRSQSSSR----------SRSRSHS---RKKRYRSRSRTYSRS 44
+G+ SRS H S+SKSRS+S R SR RS R+ R RSRS+ SRS
Sbjct: 283 VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRS 342
Query: 45 RSRDRMYSRDYR------RDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRR 98
RSR R S+D R R+ +R R R R RG + + + +R
Sbjct: 343 RSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRS 402
Query: 99 HSRSPRRGRSRSRSPKRRSVSSQR----------------SRSRSRRSYRSSRSPRSSSS 142
SRSP R S+ R +S SSQR SRSRS S P S S
Sbjct: 403 QSRSPSRSVSKERE-HAKSESSQREGRGESENAGTNQETRSRSRS-NSKSKPNLPSESRS 460
Query: 143 RSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPK 186
RS S SK R + +++ A SP +S+S+ +
Sbjct: 461 RSKS------ASKTRSRSKSRSRSA-----SRSPSRSRSRSHSR 493
Score = 55.1 bits (131), Expect = 3e-07
Identities = 72/300 (24%), Positives = 120/300 (40%), Gaps = 37/300 (12%)
Query: 96 NRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRS---SRSPRS----SSSRSSSPY 148
+R HSRS R R SR + RS SS+ S S+SR RS SRS S SRS
Sbjct: 188 SRSHSRSRSRSR-HSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEK 246
Query: 149 SKSP-----------------VSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEH 191
S+SP SK + ++ Q G+P+ SP + KS+ + +
Sbjct: 247 SRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSR---SR 303
Query: 192 DPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHS 251
++E + S + G S + RS + S+S S
Sbjct: 304 SQERRVEEEKRGSVSRGRS-QEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSRE 362
Query: 252 AKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRD 311
+ S+ + S +R GSS+ +++ RSP+++++ + R+
Sbjct: 363 ESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDT---DRSQSRSPSRSVSKE---RE 416
Query: 312 ESRGRSSFYPDGGDQETAKTGKFL--KRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRA 369
++ SS G+ E A T + + ++ +S+ L +R K ASK + K R+
Sbjct: 417 HAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRS 476
Score = 47.0 bits (110), Expect = 8e-05
Identities = 43/171 (25%), Positives = 69/171 (40%), Gaps = 25/171 (14%)
Query: 620 KSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQK 679
KS + + ++ Q + +SP H+ + +R +ER +EE +
Sbjct: 264 KSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKS--------KSKSRSRSQERRVEEEKRG 315
Query: 680 GDKKLRCDSADLRHDIDR---------RRKERSKERGDSKG---SRESSGSRKQEKTPKD 727
+ R LR R R + RSK + KG SRE S SR + ++ +
Sbjct: 316 SVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSE 375
Query: 728 YKEYKSYKDD-----SKHKREQDHSRSSSSSASPSSPSSREEKESKKEREE 773
+ K D SK K+++D RS S S S S RE +S+ + E
Sbjct: 376 RSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQRE 426
Score = 46.6 bits (109), Expect = 1e-04
Identities = 45/206 (21%), Positives = 81/206 (39%), Gaps = 15/206 (7%)
Query: 676 ENQKGDKKLRCDSADLRHDIDRRRKERSKER----GDSKGSRESSGSRKQEKTPKDYKEY 731
E++ G ++ R S H R R S++ G SK S S SR + + K
Sbjct: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSR 233
Query: 732 KSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEM-----KEYSG 786
+ S+ K+E+ S S S S S + + +SK + EE+ + + + + S
Sbjct: 234 SRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR 293
Query: 787 FAGVSRPRGTFHDDR-DDGVDYWAKRGRG-----RGTFQRGRGRFNFKKSGSSPKWTHDK 840
S+ R + R ++ RGR R + R R + + S + DK
Sbjct: 294 HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDK 353
Query: 841 YQGDGIVEDEEETMENNEEKKDRRKE 866
+G +E + + K +R ++
Sbjct: 354 RKGRKRSREESRSRSRSRSKSERSRK 379
Score = 45.4 bits (106), Expect = 2e-04
Identities = 52/246 (21%), Positives = 91/246 (36%), Gaps = 13/246 (5%)
Query: 627 NERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRC 686
+ R SY ++ +R +S + S S+ H++ R K + +
Sbjct: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQS 238
Query: 687 DSADLRHDIDRRRKERSKERGDSKG-SRESSGSRKQEKTPKDYKEYK-SYKDDSKHKREQ 744
S + KE+S+ R S G SR S + +EK + K + S+HK
Sbjct: 239 RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHK--- 295
Query: 745 DHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDG 804
S+S S S S E++ S + K+ + + S G SR R D
Sbjct: 296 --SKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKD- 352
Query: 805 VDYWAKRGRGRGTFQ-RGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDR 863
++GR R + R R R K S + + + + ++E + ++ +
Sbjct: 353 ----KRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPS 408
Query: 864 RKEEKE 869
R KE
Sbjct: 409 RSVSKE 414
Score = 43.5 bits (101), Expect = 8e-04
Identities = 75/361 (20%), Positives = 136/361 (37%), Gaps = 51/361 (14%)
Query: 429 TEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKD--------KHKEED 480
TE G K + G+R + +++ + R S ++ K +
Sbjct: 163 TEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRS 222
Query: 481 KNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS 540
++ R K ++S + +S+K K SP ++EKS R S + + + D
Sbjct: 223 RSGSRSRSKSRSRSQSRSRSKKEKSR---SP-------SKEKSRSRSHSAGKSRSKSKDQ 272
Query: 541 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTS 600
+++ D+ +P S + R + + S +E+ + K S+ S
Sbjct: 273 AEEKIQNN------DNVGKPKSRSPSRHKSKSKSRSRSQERRV----EEEKRGSVSRGRS 322
Query: 601 ESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTL 660
+ SL K + + R S K+ ++ R++S E R S S
Sbjct: 323 QE-----KSLRQSRSRSRSKGGSRS---RSRSRSKSKDKRKGRKRSREESRSRSRSRSKS 374
Query: 661 RKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDS-----KGSRES 715
+ +R G +R K + K KK D + R KER + +S +G E+
Sbjct: 375 ER-SRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESEN 433
Query: 716 SGSRKQEKT---------PKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKE 766
+G+ ++ ++ P E +S + R + SRS S+S SPS SR
Sbjct: 434 AGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
Query: 767 S 767
S
Sbjct: 494 S 494
Score = 43.1 bits (100), Expect = 0.001
Identities = 29/53 (54%), Positives = 36/53 (67%), Gaps = 6/53 (11%)
Query: 3 RSNSRSHS---SRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYS 52
RSNS+S S S+SRS+S+S++RSRS SR RS SR+ SRSRSR S
Sbjct: 445 RSNSKSKPNLPSESRSRSKSASKTRSRSKSRS---RSASRSPSRSRSRSHSRS 494
Score = 38.5 bits (88), Expect = 0.027
Identities = 56/277 (20%), Positives = 102/277 (36%), Gaps = 31/277 (11%)
Query: 615 KEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDI---SPSTLRKHTRLAGEER 671
+ Y +S + + + + + + + S KS R S S + +R R
Sbjct: 182 RRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSR 241
Query: 672 VFKEENQKGDK---KLRCDSADLRHDIDRRRKERSKERGDSKG-----------SRESSG 717
KE+++ K + R SA + + E + D+ G S+ S
Sbjct: 242 SKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSR 301
Query: 718 SRKQEKTPKDYK-----EYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKERE 772
SR QE+ ++ K +S + + R + S+ S S S S S+++++ +K
Sbjct: 302 SRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSR 361
Query: 773 EEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGS 832
EE ++ + S SR RG+ D + K R R R + K
Sbjct: 362 EESRSRSRSRSKS---ERSRKRGSKRDSKAGSSKKKKKEDTDRSQ-SRSPSR-SVSKERE 416
Query: 833 SPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 869
K + +G G E E N+E + R + +
Sbjct: 417 HAKSESSQREGRG----ESENAGTNQETRSRSRSNSK 449
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 87.4 bits (215), Expect = 5e-17
Identities = 83/224 (37%), Positives = 103/224 (45%), Gaps = 39/224 (17%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKR----------YRSRSRTYSRSRSRDRMYS 52
R +S S SS S SR+ SSSRS SRS SR +R RSRSR++SRSRSR R YS
Sbjct: 375 RRSSSSSSSSSASRT-SSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYS 433
Query: 53 RDYRRDYRNNRG-------------MRRPYGYRGRGRGYYQGGGGRYHRGG--------- 90
R R R++ G R YG R R R G RY RGG
Sbjct: 434 RSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRS-RSHSGDRYRRGGRGLRHHSSS 492
Query: 91 -YRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSR-SSSPY 148
R W+ SRS RSRS SP S S RSRSRSR S R +R ++SP
Sbjct: 493 RSRSSWSLSPSRSRSLTRSRSHSP---SPSQSRSRSRSRSQSPSPSPAREKLTRPAASPA 549
Query: 149 SKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHD 192
+ K + K+T A+ + + LK + Q+ F+ D
Sbjct: 550 VGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKAD 593
Score = 51.6 bits (122), Expect = 3e-06
Identities = 75/262 (28%), Positives = 99/262 (37%), Gaps = 27/262 (10%)
Query: 19 SSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRGRGRGY 78
S +R S ++ KR S S + SRSRSR R+ + + + G
Sbjct: 288 SYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAA 347
Query: 79 YQG-----GGGRYHRGGYRPVWN---RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 130
G GG P N RR S S S SR+ R SS RS SRSRR
Sbjct: 348 ASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSR--SSSRSSSRSRRG 405
Query: 131 ---YRSSRSPRSSS---SRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPL------- 177
YRS R RS S SRS S + S+ RG + +G SP
Sbjct: 406 GGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGP 465
Query: 178 --KSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPS 235
+S+S+ D + + S +S + P S RS HSPSP + S
Sbjct: 466 RRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRS-HSPSP-SQSRS 523
Query: 236 QSSSCSDAPMLSTVHSAKNTPS 257
+S S S +P S P+
Sbjct: 524 RSRSRSQSPSPSPAREKLTRPA 545
Score = 42.4 bits (98), Expect = 0.002
Identities = 91/431 (21%), Positives = 156/431 (36%), Gaps = 80/431 (18%)
Query: 108 SRSRSPKRRSVSSQRSRSRSRRSYRSSR------SPRSSSSRSSSPYSKSPVSKRRGSQE 161
+++ ++ S +RSR R RR +R R SP S + R S Y S S E
Sbjct: 252 AKALEEEKAMYSGRRSR-RQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSE 310
Query: 162 KQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSP 221
+++ P E K TF S DE ++A + + +P
Sbjct: 311 SRSRSRSPTPGREE----------KITFITSFGGS-DEEAAAAAAAAAASGVTTGKPPAP 359
Query: 222 RSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNG--- 278
P P+P ++ S S S+ SA T S S S S R G G +G
Sbjct: 360 PQPGGPAPGRNASARRRSSSS----SSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHA 415
Query: 279 -------------SSRYSPSQNSPIHHIPS--------RRSPAKTIAPQNAPRDESRGRS 317
S RYS S++ H RSPA+ PR SR RS
Sbjct: 416 RSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPAR--RGGYGPRRRSRSRS 473
Query: 318 SFYPDGGDQETAKTGKFLKRFTDEESR---VFLLDRGNTRDKEASKEKGSEKGRAEGEWE 374
GD+ + G+ L+ + SR R + + S + R+
Sbjct: 474 ----HSGDR-YRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSR 528
Query: 375 DQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGL 434
Q + ++ + + + G+ ++TE GK A + T +E L
Sbjct: 529 SQSPSPSPAREKLTRPAASPAVGEKLKKTE----------PAAGKETGAAKPKLTPQEKL 578
Query: 435 KYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQS 494
K + + +L NR+ F+ +K + + +H+ +++ E + ++ +
Sbjct: 579 KLRMQKAL--NRQ---FKADKK---------AAQEKMIQQEHERQEREDELRAMARKIRM 624
Query: 495 PEQVKSEKLKD 505
E+ + EK ++
Sbjct: 625 KERERREKERE 635
Score = 39.3 bits (90), Expect = 0.016
Identities = 87/404 (21%), Positives = 138/404 (34%), Gaps = 48/404 (11%)
Query: 92 RPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRS-SRSPRSSSSRSSSPYSK 150
+ +++ R SR RR R + + R +S R +Y RSP SSS S S S+
Sbjct: 259 KAMYSGRRSRRQRR-EFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRS-RSR 316
Query: 151 SPVSKRR----------GSQEKQTKKAEG---------------EPQEESPLKSKSQEEP 185
SP R GS E+ A +P +P ++ S
Sbjct: 317 SPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRR 376
Query: 186 KDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS-PIATPPSQSSSCSDAP 244
+ S S ++SS+ S Y S R S S + S+S S +
Sbjct: 377 SSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSR 436
Query: 245 MLSTVHSAKNTPSQHSHSIQHSPERSG-------SGSVGNGSSRYSPSQNSPIHHIPSRR 297
HS S+ H SP R G S S + RY HH SR
Sbjct: 437 SRGRRHSGGG--SRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRS 494
Query: 298 SPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRG-----N 352
+ +++P R S RS + Q +++ + + +R L
Sbjct: 495 RSSWSLSPS---RSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVG 551
Query: 353 TRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTE--ETEDYRQFR 410
+ K+ G E G A+ + QE L K +Q D + + + E RQ R
Sbjct: 552 EKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQER 611
Query: 411 KSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREE 454
+ L + E+E +++ + S + S + E
Sbjct: 612 EDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSRE 655
Score = 38.1 bits (87), Expect = 0.036
Identities = 48/182 (26%), Positives = 67/182 (36%), Gaps = 37/182 (20%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHS-----RKKRYRSRSRTYSRSRSRDRM-------- 50
S+SRS SS S S S+S S +RSRSHS + R RSRS++ S S +R+++
Sbjct: 490 SSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPA 549
Query: 51 ----------------------YSRDYRRDYRNNRGMRRPY--GYRGRGRGYYQGGGGRY 86
+ + R + + R + + Q R
Sbjct: 550 VGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQ 609
Query: 87 HRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSS 146
R R+ R R + R R S Q R S S S R S SRS S
Sbjct: 610 EREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRS 669
Query: 147 PY 148
P+
Sbjct: 670 PH 671
Score = 33.5 bits (75), Expect = 0.88
Identities = 21/89 (23%), Positives = 49/89 (55%), Gaps = 8/89 (8%)
Query: 662 KHTRLAGEERVFKEENQKGDKK--LRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSR 719
K + A +E++ ++E+++ +++ LR + +R +R R+E+ +E + + SR+S
Sbjct: 591 KADKKAAQEKMIQQEHERQEREDELRAMARKIRMK-ERERREKEREEWERQYSRQS---- 645
Query: 720 KQEKTPKDYKEYKSYKDDSKHKREQDHSR 748
+ +P+ +EY S + S+ + H R
Sbjct: 646 -RSPSPRYSREYSSSRRRSRSRSRSPHYR 673
Score = 33.1 bits (74), Expect = 1.1
Identities = 105/525 (20%), Positives = 179/525 (34%), Gaps = 77/525 (14%)
Query: 355 DKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSE-GDDTEETEDYRQ----F 409
+K A K + E E D++ + D E + N + D ++ Y F
Sbjct: 176 EKAAEKPEEEESAAEEESNSDEDEVIPDIDVEVDVDELNQEQVADLNKQATTYGMADGDF 235
Query: 410 RKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEK--NYKLKETGYVVE 467
+ + D+ ++ A + EEE Y + S + RE FRE++ K+ Y
Sbjct: 236 VRMLRKDKEEAEAIKHAKALEEEKAMYSGRRSRRQRRE---FREKRLRGRKISPPSYA-R 291
Query: 468 RPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFRE 527
R S T D +K S + + ++SP + EK+ + + +
Sbjct: 292 RDSPTYDPYKRSPSESSSES-RSRSRSPTPGREEKITFITSFGGS--------------D 336
Query: 528 ESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIF 587
E A+ S K P P + + + R +S+ S + RS
Sbjct: 337 EEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRS-- 394
Query: 588 DHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSP 647
+S+S+S S Y++S + A + +S
Sbjct: 395 -------SSRSSSRS----------RRGGGYYRSG-----------RHARSRSRSWSRSR 426
Query: 648 EIHRRIDISPSTLRKHTRLAGEE--RVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKE 705
RR S S R+H+ + R + ++G R S H DR R+
Sbjct: 427 SRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGL 486
Query: 706 RGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEK 765
R S SS S ++ + +S+ R + SRS S S SP+
Sbjct: 487 RHHSSSRSRSSWSLSPSRS-RSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPA 545
Query: 766 ESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGR- 824
S E+ KT + +G A +P+ T + + + Q+ R
Sbjct: 546 ASPAVGEKLKKTEPAAGKETGAA---KPKLT-------------PQEKLKLRMQKALNRQ 589
Query: 825 FNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 869
F K + K +++ EDE M K+R + EKE
Sbjct: 590 FKADKKAAQEKMIQQEHERQE-REDELRAMARKIRMKERERREKE 633
Score = 30.8 bits (68), Expect = 5.7
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 4/70 (5%)
Query: 7 RSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRS---RTYSR-SRSRDRMYSRDYRRDYRNN 62
+ H + + + + R R++R + R R YSR SRS YSR+Y R +
Sbjct: 604 QEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRS 663
Query: 63 RGMRRPYGYR 72
R R YR
Sbjct: 664 RSRSRSPHYR 673
Score = 30.4 bits (67), Expect = 7.4
Identities = 19/30 (63%), Positives = 19/30 (63%), Gaps = 1/30 (3%)
Query: 6 SRSHSSRSKSRSQSSSRSRSRSHSRKKRYR 35
SRS S R SR SSSR RSRS SR YR
Sbjct: 645 SRSPSPRY-SREYSSSRRRSRSRSRSPHYR 673
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 87.4 bits (215), Expect = 5e-17
Identities = 94/283 (33%), Positives = 128/283 (45%), Gaps = 32/283 (11%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHS--RKKRY-RSRSRTYSRSRSRDRMYSRDYRRDYR 60
S S + SS S S S SSR+ SRS S RKKR+ RSRS T RSR R YSR R
Sbjct: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR--RIKIE 583
Query: 61 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP--RRGRSRSRSPKRRSV 118
+NR + R R + RR +RSP R RSRSRS RR+
Sbjct: 584 SNRARVKIRDRRRSNRNSIER--------------ERRRNRSPSRERRRSRSRSRDRRTN 629
Query: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ--EKQTKKAEGE-PQEES 175
+ RSRSR RR R S +S +K K+ S+ +K KK + E +E+
Sbjct: 630 RASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQD 689
Query: 176 PLKSKSQEEPKD---TFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIAT 232
K K + E KD + + D + E ++ + SG I + +D+ S S + +
Sbjct: 690 KRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSK 749
Query: 233 PPSQSS----SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSG 271
S S S S++P S AK S S++ S +RSG
Sbjct: 750 KHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKS-QRSG 791
Score = 57.0 bits (136), Expect = 7e-08
Identities = 87/399 (21%), Positives = 161/399 (40%), Gaps = 54/399 (13%)
Query: 397 GDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN 456
G + ++ED R R S +D T++E L+++ + ++ +R+EK
Sbjct: 390 GYGSGDSEDERSDRGSESSD------------TDDEELRHRIR-----QKQEAFWRKEKE 432
Query: 457 YKLKETGYVVERPSTTKDKHKEED----KNSERITVKKETQSPEQVKSEKLKDLFDYSPP 512
+L + E T+ KE + K +++ + ++ V +EK + + +
Sbjct: 433 QQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSV 492
Query: 513 LHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLAST 572
L + +EK ++ R +S S + + S+ +S R +S
Sbjct: 493 LEPKKEHKEKE---KQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT-SSR 548
Query: 573 LVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTS 632
+K++ RS IK A +S S S+ + I + A + + +R S
Sbjct: 549 SSSPKRKKRHSRSRSPTIK---ARRSRSRSYSRRI--------KIESNRARVKIRDRRRS 597
Query: 633 YQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAG----EERVFKEEN---------QK 679
+ + E R +SP RR S S R+ R + + R ++ K
Sbjct: 598 NRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHK 657
Query: 680 GDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSK 739
G+ K + + ID+ RK++ KER + R+ KQ++ KD+K + S D K
Sbjct: 658 GEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE----KQKREEKDFK-FSSQDDRLK 712
Query: 740 HKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 778
KRE + + S S S S ++SKK ++ K H
Sbjct: 713 RKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKH 751
Score = 51.6 bits (122), Expect = 3e-06
Identities = 120/624 (19%), Positives = 231/624 (37%), Gaps = 107/624 (17%)
Query: 219 NSPRSPHSPSPI-ATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGN 277
+ P P +P P+ PPS+ S+ D+ + + ++ +Q++H+ P+ G V
Sbjct: 106 DQPWMPPTPGPMDIVPPSEDSNSQDSGEFAPDN--RHIFNQNNHNFGGPPDNFAVGPVNQ 163
Query: 278 GSSRY------------------------SPSQNS---PIHHIPSRRSPAKTIAPQNAPR 310
++ +P QN P +RSP Q P+
Sbjct: 164 FDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQ 223
Query: 311 DES---RGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSE-- 365
++ R ++ +G ++ + K L++ E+ R L + ++A G
Sbjct: 224 IDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLP 283
Query: 366 ---KGRAEGEWEDQEALDYFSDKESGKQKFNDS-----EGDDTEETEDYRQFRKSVLADQ 417
K ++ E ED E ++ S SGK + S E D E TE+ ++++ +L
Sbjct: 284 QRSKFDSDEEEEDTENVEAAS---SGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLT-- 338
Query: 418 GKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTK---- 473
K T + +E + Y +K D R+ K+ S T
Sbjct: 339 -KMLLTEILLDVTDEEIYYVAK---------DAHRKATKAPAKQLAQSSALASLTGLGGL 388
Query: 474 ---DKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESP 530
ED+ S+R + +T E L + ++++ +R+E
Sbjct: 389 GGYGSGDSEDERSDRGSESSDTDDEE----------------LRHRIRQKQEAFWRKEKE 432
Query: 531 LRI---KMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKE-QEFRSI 586
++ K + + + E K + SL + R +V+ K+ E S+
Sbjct: 433 QQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSV 492
Query: 587 FD----HIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHST 642
+ H + + +S S S S S + T++ S + S+
Sbjct: 493 LEPKKEHKEKEKQGRSRSGSSSSGSSS-----SNSRTSSTSSTVSSSSYSSSSGSSRTSS 547
Query: 643 RQKSPEIHRRIDIS--PSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRK 700
R SP+ +R S P+ + +R R K E+ + K+R DRRR
Sbjct: 548 RSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIR----------DRRRS 597
Query: 701 ERSKERGDSKGSRESSGSRKQEKT-PKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSP 759
R+ + + +R S R++ ++ +D + ++ + S+ +R+ D R + S S
Sbjct: 598 NRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHK 657
Query: 760 SSREEKESKKEREEEFKTHHEMKE 783
+E+E KKER + K+
Sbjct: 658 GEAKEQERKKERSRSIDKDRKKKD 681
Score = 47.4 bits (111), Expect = 6e-05
Identities = 94/472 (19%), Positives = 170/472 (36%), Gaps = 51/472 (10%)
Query: 430 EEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTK---DKHKEEDKNSERI 486
E E K K ++ R +E+K + E G P +K D+ +E+ +N E
Sbjct: 244 EREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAA 303
Query: 487 TVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFRE----ESPLRIKMIASDSHR 542
+ K T+SP V E+ D + K E + I +A D+HR
Sbjct: 304 SSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHR 363
Query: 543 PEVKLKMAPVP-LDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSE 601
K AP L S+ ASLT L + E+ R S T +
Sbjct: 364 KATK---APAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRG--------SESSDTDD 412
Query: 602 SFIQHIVSLVHHVKEQYF---KSAAMTLNERFTSYQKATEEHSTRQKSPEIHRR------ 652
++H + K++ F + L+++ +K E T++ + IH+
Sbjct: 413 EELRHRI----RQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSL 468
Query: 653 ----------IDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKER 702
++ T + T + ++ KE+ ++G + S+ R
Sbjct: 469 LEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTS 528
Query: 703 S----KERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSS 758
S S GS +S K K + +S ++ R + +SR ++ +
Sbjct: 529 STVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRAR 588
Query: 759 PSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTF 818
R+ + S + E + + SR R D R + R R +
Sbjct: 589 VKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSR----DRRTNRASRSRSRDRRKIDD 644
Query: 819 QRGRGRFN-FKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 869
QRG N K G + + K + I +D ++ + E ++D+RKE+++
Sbjct: 645 QRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQK 696
Score = 46.6 bits (109), Expect = 1e-04
Identities = 52/207 (25%), Positives = 81/207 (39%), Gaps = 21/207 (10%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
R++ R++S S+ RSRSRS R R+ SRSRSRDR D R + N
Sbjct: 599 RNSIERERRRNRSPSRERRRSRSRSRDR------RTNRASRSRSRDRRKIDDQRGNLSGN 652
Query: 63 RGMRRPYGYRGRGRGYYQGGGGRYHRG---GYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 119
++ +G Q R + R +R + R K S
Sbjct: 653 -------SHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFS 705
Query: 120 SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR---RGSQEKQTKKAEGEPQEESP 176
SQ R + +R + S S S + SK+ + S++ + G ESP
Sbjct: 706 SQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESP 765
Query: 177 LKSKSQEEPKDTFEHDPSESIDEFNKS 203
SK ++ K +H S S+++ +S
Sbjct: 766 GSSKEKKAKKP--KHSRSRSVEKSQRS 790
Score = 44.7 bits (104), Expect = 4e-04
Identities = 77/355 (21%), Positives = 129/355 (36%), Gaps = 57/355 (16%)
Query: 163 QTKKAEGEPQEE---SPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDN 219
+ ++A+G+ E +P ++ S EPK EH E S++SG
Sbjct: 470 EAREADGDVVNEKKRTPNETTSVLEPKK--EHKEKEKQGRSRSGSSSSGSSSSNSRTSST 527
Query: 220 SPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS---QHSHSIQHSPE-------- 268
S S ++ S++SS S +P HS +P+ + S S +S
Sbjct: 528 SSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRA 587
Query: 269 ----RSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGG 324
R S N R SP RS ++ A R SR R
Sbjct: 588 RVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKI----D 643
Query: 325 DQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGS--EKGRAEGEWEDQEALDYF 382
DQ +G K +G +++E KE+ +K R + + E + D
Sbjct: 644 DQRGNLSGNSHKH------------KGEAKEQERKKERSRSIDKDRKKKDKEREREQDKR 691
Query: 383 SDKESGKQK-FNDSEGDDT--EETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSK 439
+K+ ++K F S DD + E R F +S G ++ ++ K +K
Sbjct: 692 KEKQKREEKDFKFSSQDDRLKRKRESERTFSRS-----GSISVKIIRHDSRQDSKKSTTK 746
Query: 440 VSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQS 494
S K + R E P ++K+K ++ K+S +V+K +S
Sbjct: 747 DSKKHSGSDSSGRSSS-----------ESPGSSKEKKAKKPKHSRSRSVEKSQRS 790
Score = 44.7 bits (104), Expect = 4e-04
Identities = 46/179 (25%), Positives = 73/179 (40%), Gaps = 28/179 (15%)
Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRG 64
NS H +K + + RSRS RKK+ + R R + + + + +D++ +++R
Sbjct: 652 NSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRL 711
Query: 65 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSR 124
R+ R + R G V RH SR S K+ + +
Sbjct: 712 KRKRESER------------TFSRSGSISVKIIRHD-------SRQDS-KKSTTKDSKKH 751
Query: 125 SRSRRSYR-SSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQ 182
S S S R SS SP SS + +K P R S EK + + ++ KSKS+
Sbjct: 752 SGSDSSGRSSSESPGSSKEKK----AKKPKHSRSRSVEKSQRSGKKASRKH---KSKSR 803
Score = 40.0 bits (92), Expect = 0.009
Identities = 89/422 (21%), Positives = 146/422 (34%), Gaps = 76/422 (18%)
Query: 131 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFE 190
Y S S S R S R ++KQ E +E+ L K EE K E
Sbjct: 391 YGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKE-KEQQLLHDKQMEEEKQQTE 449
Query: 191 HDPSESIDEFNKSSATSGDIWPGLSA----YDNSPRSPHSPSPIATPPSQSSSCSDAPML 246
E ++EF S + A + R+P+ + + P +
Sbjct: 450 RVTKE-MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRS 508
Query: 247 STVHSAKNTPSQHSH-SIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAP 305
+ S+ + S +S S S S S S +GSSR S +SP RS + TI
Sbjct: 509 RSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKA 568
Query: 306 QNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSE 365
+ SR RS + +R E +R R RD+ S E
Sbjct: 569 RR-----SRSRS----------------YSRRIKIESNRA----RVKIRDRRRSNRNSIE 603
Query: 366 KGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATAS 425
+ R N S + + + R++ A + +S
Sbjct: 604 RERRR----------------------NRSPSRERRRSRSRSRDRRTNRASRSRS---RD 638
Query: 426 HRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSER 485
R +++ + +L GN ++ + KE +++ KDK +E +++
Sbjct: 639 RRKIDDQ------RGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDK-- 690
Query: 486 ITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDARE-KSTFREESPLRIKMIASDSHRPE 544
+KE Q E+ KD F +S + RE + TF + +K+I DS +
Sbjct: 691 ---RKEKQKREE------KD-FKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDS 740
Query: 545 VK 546
K
Sbjct: 741 KK 742
Score = 39.7 bits (91), Expect = 0.012
Identities = 139/740 (18%), Positives = 247/740 (33%), Gaps = 125/740 (16%)
Query: 58 DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRS------- 110
DY++ P G G Y+Q G G P NRR S R R RS
Sbjct: 165 DYQHGAAFGPPQG--GFHPPYWQPGPP----GPPAPPQNRRERPSSFRDRQRSPIALPVK 218
Query: 111 RSPKRRSVSSQRSRSRSRRS--YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 168
+ P + +R+ R + R + + +S +SK+ ++K T+ AE
Sbjct: 219 QEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKK---EKKATEDAE 275
Query: 169 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 228
G P +SK F+ D E D N +A+SG + S P+ HS
Sbjct: 276 GGDGPRLPQRSK--------FDSDEEEE-DTENVEAASSGKVTRSPSPV---PQEEHSDP 323
Query: 229 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNS 288
+ + ML T T + + + +
Sbjct: 324 EMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDA---------------------- 361
Query: 289 PIHHIPSRRSPAKTIAPQNAPRDESR--GRSSFYPDGGDQETAKTGKFLKRFTDEESRVF 346
H + ++PAK +A +A + G + + E + G DEE R
Sbjct: 362 ---HRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHR 418
Query: 347 LLDRGNT-----RDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTE 401
+ + ++++ +K E+ + + E +E ++ +++ E D
Sbjct: 419 IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDV 478
Query: 402 ETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKE 461
E R ++ + K H+ E++G + +S S G+ S+ + +
Sbjct: 479 VNEKKRTPNETTSVLEPKK----EHKEKEKQG-RSRSGSSSSGSSSSNSRTSSTSSTVSS 533
Query: 462 TGYVVERPST------TKDKHKEEDKNSERITVK----KETQSPEQVKSEKLKDLFDYSP 511
+ Y S+ + K K+ S T+K + ++K E +
Sbjct: 534 SSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRD 593
Query: 512 PLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLAS 571
N ++ E+ R SP R + R S ++DR
Sbjct: 594 RRRSNRNSIERERRRNRSPSR-----------------------ERRRSRSRSRDR---R 627
Query: 572 TLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFT 631
T S + ++ R I D Q + S + K++ +S ++
Sbjct: 628 TNRASRSRSRDRRKIDD-----QRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDK 682
Query: 632 SYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADL 691
++ ++ +QK E + L++ ER F K +R
Sbjct: 683 EREREQDKRKEKQKREEKDFKFSSQDDRLKRKRE---SERTFSRSGSISVKIIR------ 733
Query: 692 RHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSS 751
HD + K +S + K S S R ++P KE K+ K KH R SRS
Sbjct: 734 -HDSRQDSK-KSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKK--PKHSR----SRSVE 785
Query: 752 SSASPSSPSSREEKESKKER 771
S +SR+ K + R
Sbjct: 786 KSQRSGKKASRKHKSKSRSR 805
Score = 32.3 bits (72), Expect = 2.0
Identities = 16/48 (33%), Positives = 27/48 (56%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDR 49
GRS+S S S + +++ SRSRS + +R ++ +S+SR R
Sbjct: 758 GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 87.4 bits (215), Expect = 5e-17
Identities = 94/283 (33%), Positives = 128/283 (45%), Gaps = 32/283 (11%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHS--RKKRY-RSRSRTYSRSRSRDRMYSRDYRRDYR 60
S S + SS S S S SSR+ SRS S RKKR+ RSRS T RSR R YSR R
Sbjct: 526 STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR--RIKIE 583
Query: 61 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP--RRGRSRSRSPKRRSV 118
+NR + R R + RR +RSP R RSRSRS RR+
Sbjct: 584 SNRARVKIRDRRRSNRNSIER--------------ERRRNRSPSRERRRSRSRSRDRRTN 629
Query: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ--EKQTKKAEGE-PQEES 175
+ RSRSR RR R S +S +K K+ S+ +K KK + E +E+
Sbjct: 630 RASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQD 689
Query: 176 PLKSKSQEEPKD---TFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIAT 232
K K + E KD + + D + E ++ + SG I + +D+ S S + +
Sbjct: 690 KRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSK 749
Query: 233 PPSQSS----SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSG 271
S S S S++P S AK S S++ S +RSG
Sbjct: 750 KHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKS-QRSG 791
Score = 57.0 bits (136), Expect = 7e-08
Identities = 87/399 (21%), Positives = 161/399 (40%), Gaps = 54/399 (13%)
Query: 397 GDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN 456
G + ++ED R R S +D T++E L+++ + ++ +R+EK
Sbjct: 390 GYGSGDSEDERSDRGSESSD------------TDDEELRHRIR-----QKQEAFWRKEKE 432
Query: 457 YKLKETGYVVERPSTTKDKHKEED----KNSERITVKKETQSPEQVKSEKLKDLFDYSPP 512
+L + E T+ KE + K +++ + ++ V +EK + + +
Sbjct: 433 QQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSV 492
Query: 513 LHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLAST 572
L + +EK ++ R +S S + + S+ +S R +S
Sbjct: 493 LEPKKEHKEKE---KQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT-SSR 548
Query: 573 LVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTS 632
+K++ RS IK A +S S S+ + I + A + + +R S
Sbjct: 549 SSSPKRKKRHSRSRSPTIK---ARRSRSRSYSRRI--------KIESNRARVKIRDRRRS 597
Query: 633 YQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAG----EERVFKEEN---------QK 679
+ + E R +SP RR S S R+ R + + R ++ K
Sbjct: 598 NRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHK 657
Query: 680 GDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSK 739
G+ K + + ID+ RK++ KER + R+ KQ++ KD+K + S D K
Sbjct: 658 GEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKE----KQKREEKDFK-FSSQDDRLK 712
Query: 740 HKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTH 778
KRE + + S S S S ++SKK ++ K H
Sbjct: 713 RKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKH 751
Score = 51.6 bits (122), Expect = 3e-06
Identities = 120/624 (19%), Positives = 231/624 (37%), Gaps = 107/624 (17%)
Query: 219 NSPRSPHSPSPI-ATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGN 277
+ P P +P P+ PPS+ S+ D+ + + ++ +Q++H+ P+ G V
Sbjct: 106 DQPWMPPTPGPMDIVPPSEDSNSQDSGEFAPDN--RHIFNQNNHNFGGPPDNFAVGPVNQ 163
Query: 278 GSSRY------------------------SPSQNS---PIHHIPSRRSPAKTIAPQNAPR 310
++ +P QN P +RSP Q P+
Sbjct: 164 FDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQ 223
Query: 311 DES---RGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSE-- 365
++ R ++ +G ++ + K L++ E+ R L + ++A G
Sbjct: 224 IDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLP 283
Query: 366 ---KGRAEGEWEDQEALDYFSDKESGKQKFNDS-----EGDDTEETEDYRQFRKSVLADQ 417
K ++ E ED E ++ S SGK + S E D E TE+ ++++ +L
Sbjct: 284 QRSKFDSDEEEEDTENVEAAS---SGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLT-- 338
Query: 418 GKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTK---- 473
K T + +E + Y +K D R+ K+ S T
Sbjct: 339 -KMLLTEILLDVTDEEIYYVAK---------DAHRKATKAPAKQLAQSSALASLTGLGGL 388
Query: 474 ---DKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESP 530
ED+ S+R + +T E L + ++++ +R+E
Sbjct: 389 GGYGSGDSEDERSDRGSESSDTDDEE----------------LRHRIRQKQEAFWRKEKE 432
Query: 531 LRI---KMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKE-QEFRSI 586
++ K + + + E K + SL + R +V+ K+ E S+
Sbjct: 433 QQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSV 492
Query: 587 FD----HIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHST 642
+ H + + +S S S S S + T++ S + S+
Sbjct: 493 LEPKKEHKEKEKQGRSRSGSSSSGSSS-----SNSRTSSTSSTVSSSSYSSSSGSSRTSS 547
Query: 643 RQKSPEIHRRIDIS--PSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRK 700
R SP+ +R S P+ + +R R K E+ + K+R DRRR
Sbjct: 548 RSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIR----------DRRRS 597
Query: 701 ERSKERGDSKGSRESSGSRKQEKT-PKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSP 759
R+ + + +R S R++ ++ +D + ++ + S+ +R+ D R + S S
Sbjct: 598 NRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHK 657
Query: 760 SSREEKESKKEREEEFKTHHEMKE 783
+E+E KKER + K+
Sbjct: 658 GEAKEQERKKERSRSIDKDRKKKD 681
Score = 47.4 bits (111), Expect = 6e-05
Identities = 94/472 (19%), Positives = 170/472 (36%), Gaps = 51/472 (10%)
Query: 430 EEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTK---DKHKEEDKNSERI 486
E E K K ++ R +E+K + E G P +K D+ +E+ +N E
Sbjct: 244 EREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAA 303
Query: 487 TVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFRE----ESPLRIKMIASDSHR 542
+ K T+SP V E+ D + K E + I +A D+HR
Sbjct: 304 SSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHR 363
Query: 543 PEVKLKMAPVP-LDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSE 601
K AP L S+ ASLT L + E+ R S T +
Sbjct: 364 KATK---APAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRG--------SESSDTDD 412
Query: 602 SFIQHIVSLVHHVKEQYF---KSAAMTLNERFTSYQKATEEHSTRQKSPEIHRR------ 652
++H + K++ F + L+++ +K E T++ + IH+
Sbjct: 413 EELRHRI----RQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSL 468
Query: 653 ----------IDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKER 702
++ T + T + ++ KE+ ++G + S+ R
Sbjct: 469 LEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTS 528
Query: 703 S----KERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSS 758
S S GS +S K K + +S ++ R + +SR ++ +
Sbjct: 529 STVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRAR 588
Query: 759 PSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTF 818
R+ + S + E + + SR R D R + R R +
Sbjct: 589 VKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSR----DRRTNRASRSRSRDRRKIDD 644
Query: 819 QRGRGRFN-FKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 869
QRG N K G + + K + I +D ++ + E ++D+RKE+++
Sbjct: 645 QRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQK 696
Score = 46.6 bits (109), Expect = 1e-04
Identities = 52/207 (25%), Positives = 81/207 (39%), Gaps = 21/207 (10%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
R++ R++S S+ RSRSRS R R+ SRSRSRDR D R + N
Sbjct: 599 RNSIERERRRNRSPSRERRRSRSRSRDR------RTNRASRSRSRDRRKIDDQRGNLSGN 652
Query: 63 RGMRRPYGYRGRGRGYYQGGGGRYHRG---GYRPVWNRRHSRSPRRGRSRSRSPKRRSVS 119
++ +G Q R + R +R + R K S
Sbjct: 653 -------SHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFS 705
Query: 120 SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR---RGSQEKQTKKAEGEPQEESP 176
SQ R + +R + S S S + SK+ + S++ + G ESP
Sbjct: 706 SQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESP 765
Query: 177 LKSKSQEEPKDTFEHDPSESIDEFNKS 203
SK ++ K +H S S+++ +S
Sbjct: 766 GSSKEKKAKKP--KHSRSRSVEKSQRS 790
Score = 44.7 bits (104), Expect = 4e-04
Identities = 77/355 (21%), Positives = 129/355 (36%), Gaps = 57/355 (16%)
Query: 163 QTKKAEGEPQEE---SPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDN 219
+ ++A+G+ E +P ++ S EPK EH E S++SG
Sbjct: 470 EAREADGDVVNEKKRTPNETTSVLEPKK--EHKEKEKQGRSRSGSSSSGSSSSNSRTSST 527
Query: 220 SPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS---QHSHSIQHSPE-------- 268
S S ++ S++SS S +P HS +P+ + S S +S
Sbjct: 528 SSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRA 587
Query: 269 ----RSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGG 324
R S N R SP RS ++ A R SR R
Sbjct: 588 RVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKI----D 643
Query: 325 DQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGS--EKGRAEGEWEDQEALDYF 382
DQ +G K +G +++E KE+ +K R + + E + D
Sbjct: 644 DQRGNLSGNSHKH------------KGEAKEQERKKERSRSIDKDRKKKDKEREREQDKR 691
Query: 383 SDKESGKQK-FNDSEGDDT--EETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSK 439
+K+ ++K F S DD + E R F +S G ++ ++ K +K
Sbjct: 692 KEKQKREEKDFKFSSQDDRLKRKRESERTFSRS-----GSISVKIIRHDSRQDSKKSTTK 746
Query: 440 VSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQS 494
S K + R E P ++K+K ++ K+S +V+K +S
Sbjct: 747 DSKKHSGSDSSGRSSS-----------ESPGSSKEKKAKKPKHSRSRSVEKSQRS 790
Score = 44.7 bits (104), Expect = 4e-04
Identities = 46/179 (25%), Positives = 73/179 (40%), Gaps = 28/179 (15%)
Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRG 64
NS H +K + + RSRS RKK+ + R R + + + + +D++ +++R
Sbjct: 652 NSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRL 711
Query: 65 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSR 124
R+ R + R G V RH SR S K+ + +
Sbjct: 712 KRKRESER------------TFSRSGSISVKIIRHD-------SRQDS-KKSTTKDSKKH 751
Query: 125 SRSRRSYR-SSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQ 182
S S S R SS SP SS + +K P R S EK + + ++ KSKS+
Sbjct: 752 SGSDSSGRSSSESPGSSKEKK----AKKPKHSRSRSVEKSQRSGKKASRKH---KSKSR 803
Score = 40.0 bits (92), Expect = 0.009
Identities = 89/422 (21%), Positives = 146/422 (34%), Gaps = 76/422 (18%)
Query: 131 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFE 190
Y S S S R S R ++KQ E +E+ L K EE K E
Sbjct: 391 YGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKE-KEQQLLHDKQMEEEKQQTE 449
Query: 191 HDPSESIDEFNKSSATSGDIWPGLSA----YDNSPRSPHSPSPIATPPSQSSSCSDAPML 246
E ++EF S + A + R+P+ + + P +
Sbjct: 450 RVTKE-MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRS 508
Query: 247 STVHSAKNTPSQHSH-SIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAP 305
+ S+ + S +S S S S S S +GSSR S +SP RS + TI
Sbjct: 509 RSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKA 568
Query: 306 QNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSE 365
+ SR RS + +R E +R R RD+ S E
Sbjct: 569 RR-----SRSRS----------------YSRRIKIESNRA----RVKIRDRRRSNRNSIE 603
Query: 366 KGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATAS 425
+ R N S + + + R++ A + +S
Sbjct: 604 RERRR----------------------NRSPSRERRRSRSRSRDRRTNRASRSRS---RD 638
Query: 426 HRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSER 485
R +++ + +L GN ++ + KE +++ KDK +E +++
Sbjct: 639 RRKIDDQ------RGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDK-- 690
Query: 486 ITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDARE-KSTFREESPLRIKMIASDSHRPE 544
+KE Q E+ KD F +S + RE + TF + +K+I DS +
Sbjct: 691 ---RKEKQKREE------KD-FKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDS 740
Query: 545 VK 546
K
Sbjct: 741 KK 742
Score = 39.7 bits (91), Expect = 0.012
Identities = 139/740 (18%), Positives = 247/740 (33%), Gaps = 125/740 (16%)
Query: 58 DYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRS------- 110
DY++ P G G Y+Q G G P NRR S R R RS
Sbjct: 165 DYQHGAAFGPPQG--GFHPPYWQPGPP----GPPAPPQNRRERPSSFRDRQRSPIALPVK 218
Query: 111 RSPKRRSVSSQRSRSRSRRS--YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 168
+ P + +R+ R + R + + +S +SK+ ++K T+ AE
Sbjct: 219 QEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKK---EKKATEDAE 275
Query: 169 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 228
G P +SK F+ D E D N +A+SG + S P+ HS
Sbjct: 276 GGDGPRLPQRSK--------FDSDEEEE-DTENVEAASSGKVTRSPSPV---PQEEHSDP 323
Query: 229 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNS 288
+ + ML T T + + + +
Sbjct: 324 EMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDA---------------------- 361
Query: 289 PIHHIPSRRSPAKTIAPQNAPRDESR--GRSSFYPDGGDQETAKTGKFLKRFTDEESRVF 346
H + ++PAK +A +A + G + + E + G DEE R
Sbjct: 362 ---HRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHR 418
Query: 347 LLDRGNT-----RDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTE 401
+ + ++++ +K E+ + + E +E ++ +++ E D
Sbjct: 419 IRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDV 478
Query: 402 ETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKE 461
E R ++ + K H+ E++G + +S S G+ S+ + +
Sbjct: 479 VNEKKRTPNETTSVLEPKK----EHKEKEKQG-RSRSGSSSSGSSSSNSRTSSTSSTVSS 533
Query: 462 TGYVVERPST------TKDKHKEEDKNSERITVK----KETQSPEQVKSEKLKDLFDYSP 511
+ Y S+ + K K+ S T+K + ++K E +
Sbjct: 534 SSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRD 593
Query: 512 PLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLAS 571
N ++ E+ R SP R + R S ++DR
Sbjct: 594 RRRSNRNSIERERRRNRSPSR-----------------------ERRRSRSRSRDR---R 627
Query: 572 TLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFT 631
T S + ++ R I D Q + S + K++ +S ++
Sbjct: 628 TNRASRSRSRDRRKIDD-----QRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDK 682
Query: 632 SYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADL 691
++ ++ +QK E + L++ ER F K +R
Sbjct: 683 EREREQDKRKEKQKREEKDFKFSSQDDRLKRKRE---SERTFSRSGSISVKIIR------ 733
Query: 692 RHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSS 751
HD + K +S + K S S R ++P KE K+ K KH R SRS
Sbjct: 734 -HDSRQDSK-KSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKK--PKHSR----SRSVE 785
Query: 752 SSASPSSPSSREEKESKKER 771
S +SR+ K + R
Sbjct: 786 KSQRSGKKASRKHKSKSRSR 805
Score = 32.3 bits (72), Expect = 2.0
Identities = 16/48 (33%), Positives = 27/48 (56%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDR 49
GRS+S S S + +++ SRSRS + +R ++ +S+SR R
Sbjct: 758 GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 86.3 bits (212), Expect = 1e-16
Identities = 197/936 (21%), Positives = 347/936 (37%), Gaps = 110/936 (11%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
RS SRS S S S SS + S+S S R RS SR++SRS SR S Y R
Sbjct: 681 RSFSRSKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYP---RRG 737
Query: 63 RGMRRPYGYRGRGRGYYQGGGGRYHRGGYR-PVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 121
RG R Y R R G YHR R P + R HSRS R +SP +R+V
Sbjct: 738 RGKSRNYRSRSRSHG--------YHRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQG 789
Query: 122 RSRSRSRRSYRSSRSPRSSSS-RSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK 180
+ YR P + S + P K R +E + K E + +
Sbjct: 790 ETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKER-YREWERKYREWYEKYYKGYAAG 848
Query: 181 SQEEPKDTFEHDPSESIDEFN--KSSATSG--DIWPGLSAYDNSPRSPHSPSPIATPPSQ 236
+Q P E+ E N S T G + + G ++ + + P ++
Sbjct: 849 AQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGH 908
Query: 237 SSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVG---------NGSSR----YS 283
+ + +A + H +H R G S G + SR
Sbjct: 909 NQKDNTKSKEKESENAPGDGKGNKHK-KHRKRRKGEESEGFLNPELLETSRKSREPTGVE 967
Query: 284 PSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKT-GKFLKRFTD-- 340
++ + +PS R A + + + +S D +++ K G KR D
Sbjct: 968 ENKTDSLFVLPS-RDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGS 1026
Query: 341 ---EESRVFLLDRG------NTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKE----S 387
++ + +G R++ E +K + E D S K+
Sbjct: 1027 AVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITG 1086
Query: 388 GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRE 447
+K + + +ET+ ++ + V D K + EE+ K K N+
Sbjct: 1087 TPRKAHSKSAKEHQETKPVKE--EKVKKDYSKDVKSEKLTTKEEKAKKPNEK-----NKP 1139
Query: 448 SDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKL--KD 505
D E++ K +E G + S++ K E + + K++ + P+ K ++ KD
Sbjct: 1140 LDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKME-PDTEKMDRTPEKD 1198
Query: 506 LFDYSPPLH---------KNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDD 556
S P K + + E + +E +++ +S + +VK K+
Sbjct: 1199 KISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGT 1258
Query: 557 SNRPASLTKDRLLASTLVHSVKKEQE----FRSIFDHIKLPQASKSTSESFIQHIVSLVH 612
++L +ST V+K +E R++ IK + + + + + ++ ++
Sbjct: 1259 EGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTV---IKTMEEYNNDNTAPAEDVIIMIQ 1315
Query: 613 HVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERV 672
+ ++ K + E K+T+ S+ K + + + PS + K+ E
Sbjct: 1316 VPQSKWDKDDFESEEEDV----KSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEP-- 1369
Query: 673 FKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKG------SRESSGSRKQEKTPK 726
E+ QK K + + ++H++ + S E+G +K +E+ RK P+
Sbjct: 1370 -SEKIQKFTKDVSHEI--IQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPE 1426
Query: 727 ---------DYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKT 777
+ +KS SK R D S+ +S++ +R++K RE
Sbjct: 1427 KESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSK 1486
Query: 778 HHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP--- 834
+ K ++R + + ++D K R ++G G + KKS SSP
Sbjct: 1487 RRDEKN-----ELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTG--DSKKSNSSPSRD 1539
Query: 835 KWTHD-KYQGDGIVEDEEETMENNEEKKDRRKEEKE 869
+ HD K D +EE + KDR K E
Sbjct: 1540 RKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLE 1575
Score = 76.3 bits (186), Expect = 1e-13
Identities = 147/749 (19%), Positives = 295/749 (39%), Gaps = 110/749 (14%)
Query: 101 RSPRRG----RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSP--------- 147
RSPR +++ +PK + +S S S++ + + +PR + S+S+
Sbjct: 1051 RSPRSEPPIKKAKEETPK---TDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKE 1107
Query: 148 ------YSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFN 201
YSK S++ ++E++ KK ++ PL +K ++ + T E + +D+
Sbjct: 1108 EKVKKDYSKDVKSEKLTTKEEKAKKPN---EKNKPLDNKGEKRKRKTEE----KGVDKDF 1160
Query: 202 KSSATSGDIWPGLSAYDNSPR---SPHSPSPIATPPSQSSSCSDAPM------------L 246
+SS+ SP+ P + TP S S AP +
Sbjct: 1161 ESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLS-APAKKIKLNRETGKKI 1219
Query: 247 STVHSAKNT--PSQHSHS---------IQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPS 295
+ + NT PS+ S ++ R +G+ G+ S+ + S P
Sbjct: 1220 GSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPV 1279
Query: 296 RRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRD 355
R+S KT D R + + TA + +S+ + D
Sbjct: 1280 RKSEEKT--------DTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSK------WDKDD 1325
Query: 356 KEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLA 415
E+ +E + + S K S K+ + E +E +E ++F K V
Sbjct: 1326 FESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKE---SEPSEKIQKFTKDVSH 1382
Query: 416 D-------QGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNY-KLKETGYVVE 467
+ K+ A++ T++ K + + + S +E N +L E G
Sbjct: 1383 EIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKS 1442
Query: 468 RPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFRE 527
++K+ + +S R + K+ K++ D +YS K D + + T R+
Sbjct: 1443 LSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDY--DTREYSSS--KRRDEKNELTRRK 1498
Query: 528 ESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIF 587
+SP R K AS P ++ + P T D +++ +K + ++ +
Sbjct: 1499 DSPSRNKDSASGQKNK---------PREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATY 1549
Query: 588 DHIKLPQASKSTSESFIQ----HIVSLVHHVKEQYFKSAAMTLNERFTSYQK----ATEE 639
D + + +KS ++ + H++ ++ KE LN T +K +
Sbjct: 1550 DTKRPNEETKSVDKNPCKDREKHVLEARNN-KESSGNKLLYILNPPETQVEKEQITGQID 1608
Query: 640 HSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCD--SADLRHDIDR 697
ST + P++ +S S L + T A E + E + + + ++ + S ++ D+
Sbjct: 1609 KSTVKPKPQLSHSSRLS-SDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKD 1667
Query: 698 RRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPS 757
+ E++KE D+ + SR Q + +S+ R S SSS+S++ S
Sbjct: 1668 KIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTR----SHSSSASSAES 1723
Query: 758 SPSSREEKESKKEREEEFKTHHEMKEYSG 786
S +++K+ +K++ ++ K H + K+++G
Sbjct: 1724 QDSKKKKKKKEKKKHKKHKKHKKHKKHAG 1752
Score = 47.0 bits (110), Expect = 8e-05
Identities = 82/434 (18%), Positives = 168/434 (38%), Gaps = 60/434 (13%)
Query: 94 VWNRRHSRSPRRGRSRSR--------SPKRRSVSSQRSRSRS-----RRSYRSSRSPRSS 140
V + ++S S +G+++ R +P++R S+Q + + + S S S
Sbjct: 1389 VKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSK 1448
Query: 141 SSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEF 200
+R+S + + S + + KK + + +E S K + ++ + PS
Sbjct: 1449 EARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSR----- 1503
Query: 201 NKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNT----- 255
NK SA S N PR T S+ S+ S + H K T
Sbjct: 1504 NKDSA---------SGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKP-HDHKATYDTKR 1553
Query: 256 PSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRG 315
P++ + S+ +P + V + S N ++ + +P +T +++ G
Sbjct: 1554 PNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYIL----NPPET----QVEKEQITG 1605
Query: 316 ---RSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGE 372
+S+ P +++ L R TDE + + ++ + KE+ S G +
Sbjct: 1606 QIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESS-GNISKD 1664
Query: 373 WEDQ------EALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASH 426
+D+ E+LD + + G + + + S Q +S ++++
Sbjct: 1665 LKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSH-----SPSGSQTRSHSSSAS 1719
Query: 427 RNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERI 486
++ K K K K +++ ++ K K G VE + K KHK++ +
Sbjct: 1720 SAESQDSKKKKKKKEKKKHKKHKKHKKHK----KHAGTEVELEKSQKHKHKKKKSKKNKD 1775
Query: 487 TVKKETQSPEQVKS 500
K++ + ++VKS
Sbjct: 1776 KEKEKEKDDQKVKS 1789
Score = 45.1 bits (105), Expect = 3e-04
Identities = 66/299 (22%), Positives = 114/299 (38%), Gaps = 27/299 (9%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSH-----SRKKRYRSRSRTYSRSRSRDRMYSRDYR 56
G S S SS+ S +R+ S+ +R K+ +R YS S+ RD R
Sbjct: 1438 GNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRR 1497
Query: 57 RD--YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPK 114
+D RN R + G G + P +R+ ++ + +
Sbjct: 1498 KDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEE 1557
Query: 115 RRSVSSQRSRSRSRRSYRSSRSPRSSSSR----SSSPYSKSPVSKRRGSQEKQTKKAEGE 170
+SV + R + + + SS ++ + P ++ + G +K T K + +
Sbjct: 1558 TKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQ 1617
Query: 171 PQEESPLKSK-SQEEPKDTFEHDPSESIDEFN---KSSATSGDIWPGL--SAYDNSPRSP 224
S L S ++E + FE D +ES E N K +SG+I L + + S
Sbjct: 1618 LSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESL 1677
Query: 225 HSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYS 283
+ + + S++ S HS+ + SHS S RS S S + S+ S
Sbjct: 1678 DTAAVVQVGISRNQS----------HSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDS 1726
Score = 40.0 bits (92), Expect = 0.009
Identities = 114/639 (17%), Positives = 224/639 (35%), Gaps = 83/639 (12%)
Query: 132 RSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEH 191
+ R+P S+P K +++ G + T+ + L+S S + ++ +
Sbjct: 1190 KMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKG 1249
Query: 192 DPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHS 251
+ SS+T D + S SP+ ++ + ++
Sbjct: 1250 KVRRKVTGTEGSSST---------LVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYN 1300
Query: 252 AKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIA--PQNAP 309
NT I +S S PI + S K ++ P N
Sbjct: 1301 NDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIV 1360
Query: 310 RDESRGRSSFYPDGGDQETAKTGKFLKRFTDE--------ESRVFLLDRGNTRDKEAS-- 359
+ YP+ + + K KF K + E ++G T+D++ S
Sbjct: 1361 K---------YPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVL 1411
Query: 360 KEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGK 419
+++ EK + + E + LD +++ + K S+ T + D S A K
Sbjct: 1412 EKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHD------STRASSNK 1465
Query: 420 SFATASHRNTEEEGLKYKS-------------KVSLKGNRESDGF-----REEKNYKLKE 461
F + T+ + +Y S K S N++S REE++ K
Sbjct: 1466 DFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKG 1525
Query: 462 TGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDARE 521
TG + S+ K D + T K+ + + V KD + L+AR
Sbjct: 1526 TGDSKKSNSSPSRDRKPHDHKATYDT-KRPNEETKSVDKNPCKDREKHV------LEARN 1578
Query: 522 KSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQ 581
+E S ++ I + PE +++ + ++ K +L S+ + S +
Sbjct: 1579 N---KESSGNKLLYILNP---PETQVEKEQIT-GQIDKSTVKPKPQLSHSSRLSSDLTRE 1631
Query: 582 EFRSIFDHIKLPQASKSTSESFI-----QHIVSLVHHVKEQYFKSAAMTLNERFTSYQKA 636
+ F+ P ++S SES + + ++ +K++ + A +L+
Sbjct: 1632 TDEAAFE----PDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGI 1687
Query: 637 TEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGE------ERVFKEENQKGDKKLRCDSAD 690
+ S S R S S R H+ A ++ K++ +K KK +
Sbjct: 1688 SRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKH 1747
Query: 691 LRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYK 729
+H E+S++ K + + +++EK D K
Sbjct: 1748 KKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQK 1786
Score = 34.7 bits (78), Expect = 0.39
Identities = 78/417 (18%), Positives = 136/417 (32%), Gaps = 49/417 (11%)
Query: 7 RSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSR--DYRRDYRNNRG 64
+ + + K+ +Q S + + ++S S++ +R+ D+ S +D+ NR
Sbjct: 1413 KENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRD 1472
Query: 65 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSR 124
+ Y R RR ++ R S S + S S Q+++
Sbjct: 1473 KKTDYDTREYSSS------------------KRRDEKNELTRRKDSPSRNKDSASGQKNK 1514
Query: 125 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEE 184
R R + S S SS + P + K+ P EE+ KS +
Sbjct: 1515 PREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKR-------PNEET--KSVDKNP 1565
Query: 185 PKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAP 244
KD +H + E + +SG+ Y +P T S+ P
Sbjct: 1566 CKDREKH-----VLEARNNKESSGN----KLLYILNPPETQVEKEQITGQIDKSTVKPKP 1616
Query: 245 MLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGN-------GSSRYSPSQNSPIHHIPSRR 297
LS + ++ + P+ + S S N S S I
Sbjct: 1617 QLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKES 1676
Query: 298 SPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLD-RGNTRDK 356
+ R++S S P + + +G + + S D + + K
Sbjct: 1677 LDTAAVVQVGISRNQSHSSPSVSPS---RSHSPSGSQTRSHSSSASSAESQDSKKKKKKK 1733
Query: 357 EASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSV 413
E K K +K + + E S K K+K + D +E E Q KSV
Sbjct: 1734 EKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSV 1790
Score = 30.8 bits (68), Expect = 5.7
Identities = 17/65 (26%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Query: 1 MGRSNSRSHSSRS--KSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRD 58
+G S ++SHSS S SRS S S S++RSHS + + + +++ + +++
Sbjct: 1685 VGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKH 1744
Query: 59 YRNNR 63
++ +
Sbjct: 1745 KKHKK 1749
Score = 30.0 bits (66), Expect = 9.7
Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 10/101 (9%)
Query: 511 PPLHKNLDAREKSTF-REESPLRIKMIASDSH-RPEVKLKMA-------PVPLDDSNRPA 561
P + +NL +S R++ PL I + +S +H P + + PV + S+ PA
Sbjct: 348 PLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLAPPVSGNPSSAPA 407
Query: 562 SLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSES 602
+ S VHS K + FR D+ LP A+ ++ S
Sbjct: 408 PVPDITATVSISVHSEKSDGPFRD-SDNKILPAAALASEHS 447
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 85.5 bits (210), Expect = 2e-16
Identities = 62/195 (31%), Positives = 94/195 (48%), Gaps = 6/195 (3%)
Query: 11 SRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYG 70
SRS+ R +S SRSR R R+ R R R + R R RDR Y ++ + R R
Sbjct: 330 SRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERS 389
Query: 71 YRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRS 130
R RG + + + R ++R S+ ++ SRSRS +R+ S RSR+ +RS
Sbjct: 390 KEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKK-HSRSRSRERKHRSRSRSRNAGKRS 448
Query: 131 YRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKD--- 187
SRS SS + KS R GSQ + + + +E SP K KS++ +
Sbjct: 449 --RSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKER 506
Query: 188 TFEHDPSESIDEFNK 202
+ + D S+S D+ +K
Sbjct: 507 SHKRDHSDSKDQSDK 521
Score = 57.8 bits (138), Expect = 4e-08
Identities = 55/185 (29%), Positives = 78/185 (42%), Gaps = 22/185 (11%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRD------RMYSRDY 55
GR R + K R + R RS R K RSR + D R RD
Sbjct: 363 GRRRDRDYD---KERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDS 419
Query: 56 RRDYRNNRGMRRPYGYRGRGRGYYQGGGGRY--------HRGGYRPVWNRRHSRSPRRGR 107
+++ +++R R +R R R G R H+ + N+R SRS +GR
Sbjct: 420 KKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKR-SRSGSQGR 478
Query: 108 SRS--RSPKR-RSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYS-KSPVSKRRGSQEKQ 163
+ S +S KR S S ++SR RSR RS + S S S + + S + SQEKQ
Sbjct: 479 TDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQ 538
Query: 164 TKKAE 168
K +
Sbjct: 539 HKNKD 543
Score = 55.1 bits (131), Expect = 3e-07
Identities = 57/266 (21%), Positives = 113/266 (42%), Gaps = 23/266 (8%)
Query: 613 HVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERV 672
HV+ + +S +L+ R + + + H HR S S R+ R +R+
Sbjct: 254 HVERRRSRSPRRSLSPRRSPRRSRSRSH---------HREGHGSSSFDRELEREKERQRL 304
Query: 673 FKEENQKGDKKLRCDSADLRHDIDRRR-----KERSKERG-DSKGSRESSGSRKQEKTPK 726
+E ++ ++ R S D ++RRR + RS+ R D KG R ++++ +
Sbjct: 305 EREAKEREKERRRSRSID--RGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENER 362
Query: 727 DYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSG 786
+ + Y + ++RE++ RS S S EEK+ K+++++ + H + K S
Sbjct: 363 GRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDD--RRHRDDKRDSK 420
Query: 787 FA---GVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQG 843
SR R H R + KR R R + + + K+ + + + +
Sbjct: 421 KEKKHSRSRSRERKHRSRSRSRNA-GKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRT 479
Query: 844 DGIVEDEEETMENNEEKKDRRKEEKE 869
D + + ++ ++EK +R KE
Sbjct: 480 DSVEKSKKREHSPSKEKSRKRSRSKE 505
Score = 53.9 bits (128), Expect = 6e-07
Identities = 60/254 (23%), Positives = 103/254 (40%), Gaps = 22/254 (8%)
Query: 292 HIPSRRS--PAKTIAPQNAPRD--------ESRGRSSFYPD-GGDQETAKTGKFLKRFTD 340
H+ RRS P ++++P+ +PR E G SSF + ++E + + K
Sbjct: 254 HVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREK 313
Query: 341 EESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDT 400
E R +DRG R + S+E+ + R+ D+ D +KE+ + + D + D
Sbjct: 314 ERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKE 373
Query: 401 EETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLK 460
E ++ +S + +S S EE+ K K R D R+ K K
Sbjct: 374 RGNEREKERERS----RERSKEQRSRGEVEEK----KHKEDKDDRRHRDDKRDSKKEKKH 425
Query: 461 ETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAR 520
ER ++ + + K S + +K ++ + K + K S D+
Sbjct: 426 SRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGS---QGRTDSV 482
Query: 521 EKSTFREESPLRIK 534
EKS RE SP + K
Sbjct: 483 EKSKKREHSPSKEK 496
Score = 50.1 bits (118), Expect = 9e-06
Identities = 70/315 (22%), Positives = 127/315 (40%), Gaps = 46/315 (14%)
Query: 499 KSEKLKDLFDYSP-PLHKNLDAREKSTFR----------EESPLRIKMIASDSHRPEVKL 547
K E LF P P+ KN+D + K+ R EE ++ S S R +
Sbjct: 210 KLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSP 269
Query: 548 KMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHI 607
+ +P +R S ++ +S+ +++E+E + + K + + S S + +
Sbjct: 270 RRSP----RRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGL 325
Query: 608 VSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLA 667
+E++ +S + + + + + E ++ R D R+ R
Sbjct: 326 ERRRSRSRERH-RSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERER 384
Query: 668 GEERVFKEENQKGD---KKLRCDSADLRHDIDRR---------------RKERSKERGDS 709
ER KE+ +G+ KK + D D RH D+R RK RS+ R +
Sbjct: 385 SRERS-KEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRN 443
Query: 710 KGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPS-----SPSSREE 764
G R S SR +EK+ K +K+ + +KR + S+ + S S SPS +
Sbjct: 444 AGKR--SRSRSKEKSSK----HKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKS 497
Query: 765 KESKKEREEEFKTHH 779
++ + +E K H
Sbjct: 498 RKRSRSKERSHKRDH 512
Score = 48.1 bits (113), Expect = 3e-05
Identities = 71/313 (22%), Positives = 111/313 (35%), Gaps = 24/313 (7%)
Query: 18 QSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRGRGRG 77
Q + + ++ RK + + R +R SR RR R RR R R
Sbjct: 226 QKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRR-----SRSRS 280
Query: 78 YYQGGGGR--YHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRS-S 134
+++ G G + R R +R R + R + +R RSRSR +RS S
Sbjct: 281 HHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRS 340
Query: 135 RSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPS 194
RS R + ++R +++ K G +E K +E ++ + S
Sbjct: 341 RSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNERE------KERERSRERSKEQRS 394
Query: 195 ESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCS-DAPMLSTVHSAK 253
E K D D+ HS S +S S S +A S S +
Sbjct: 395 RGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKE 454
Query: 254 NTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDES 313
+ + S + S +RS SGS G S ++ H PS+ K R +
Sbjct: 455 KSSKHKNESKEKSNKRSRSGSQGRTD---SVEKSKKREHSPSKEKSRK------RSRSKE 505
Query: 314 RGRSSFYPDGGDQ 326
R + D DQ
Sbjct: 506 RSHKRDHSDSKDQ 518
Score = 43.5 bits (101), Expect = 8e-04
Identities = 55/267 (20%), Positives = 110/267 (41%), Gaps = 21/267 (7%)
Query: 249 VHSAKNTPSQHSHSIQHSPERSGSGS---VGNGSSRYSPSQNSPIHHIPSRRSPAKTIAP 305
V ++ + S S + SP RS S S G+GSS + R +
Sbjct: 255 VERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKE 314
Query: 306 QNAPRDESRG----RSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKE 361
+ R RG RS + ++ K +R D E R +RG RD++ KE
Sbjct: 315 RRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRE-REKENERGRRRDRDYDKE 373
Query: 362 KGSEKG----RAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQF-------R 410
+G+E+ R+ ++Q + +K+ + K + DD +++ ++ R
Sbjct: 374 RGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRER 433
Query: 411 KSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPS 470
K + ++ S ++E+ K+K++ K N+ S + + ++++ PS
Sbjct: 434 KHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPS 493
Query: 471 TTKDKHKEEDKNSERITVKKETQSPEQ 497
K+K ++ ++ ER + + S +Q
Sbjct: 494 --KEKSRKRSRSKERSHKRDHSDSKDQ 518
Score = 43.1 bits (100), Expect = 0.001
Identities = 31/146 (21%), Positives = 60/146 (41%), Gaps = 6/146 (4%)
Query: 638 EEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGD----KKLRCDSADLRH 693
E+ K HR +KH+R ER + ++ + + R +H
Sbjct: 400 EKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKH 459
Query: 694 DIDRRRKERSKERGDSKGSRES-SGSRKQEKTP-KDYKEYKSYKDDSKHKREQDHSRSSS 751
+ + K + R S+G +S S+K+E +P K+ +S + HKR+ S+ S
Sbjct: 460 KNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQS 519
Query: 752 SSASPSSPSSREEKESKKEREEEFKT 777
S E++ +K+ + + +T
Sbjct: 520 DKHDRRRSQSIEQESQEKQHKNKDET 545
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/182 (20%), Positives = 78/182 (42%), Gaps = 8/182 (4%)
Query: 691 LRHDIDRRRKERSKE-RGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRS 749
++ +ID++ K R ++ + D K E + + + + S + + R + H R
Sbjct: 225 VQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHRE 284
Query: 750 SSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWA 809
S+S RE++ + ERE + + + S G+ R R +
Sbjct: 285 GHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRS-----R 339
Query: 810 KRGRGRGTFQRGRGRFNFKKS--GSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEE 867
R R R +R R R K++ G +DK +G+ ++ E + E ++E++ R + E
Sbjct: 340 SRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVE 399
Query: 868 KE 869
++
Sbjct: 400 EK 401
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 85.1 bits (209), Expect = 3e-16
Identities = 192/955 (20%), Positives = 345/955 (36%), Gaps = 171/955 (17%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSR-----------KKRYRSRSRTYSRSRSRDRMYS 52
S SRS S+RS+S S+S SRS SRS+SR + YRSRSR++ RSR R S
Sbjct: 669 SKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSR--S 726
Query: 53 RDYRRDYRNNRGMRRPYGYRGRG---RGYYQGGGGRYHRGGYRPV--------------- 94
YRR + +R P +RG+ R QG R + YR V
Sbjct: 727 PPYRRYHSRSRS---PQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVD 783
Query: 95 -------------------WNRRHSRSPRRGRSRSRSPKRRSVSSQR-----------SR 124
W ++ + G S R + S +R +R
Sbjct: 784 FRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTR 843
Query: 125 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEE 184
R R Y +S RS + S+ P +S R G +K K++ + E +P K +
Sbjct: 844 GR-REDYVGGQSHRSRNIGSNYP---EKLSARDGHNQKDNTKSKEKESENAPGDGKGNKH 899
Query: 185 PKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSP-----HSPSPIATPPSQ--S 237
K + K + G + P L R P + + PS+ +
Sbjct: 900 KKHR----------KRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDA 949
Query: 238 SSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRR 297
+ D PM + + K+ + + N S S +N
Sbjct: 950 TPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKEN---------- 999
Query: 298 SPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKE 357
+ P P+++ DG + + ++ +K+ +E + NT+
Sbjct: 1000 ----IVKPAKGPQEK--------VDGERERSPRSEPPIKKAKEETPKT-----DNTKSSS 1042
Query: 358 ASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQ 417
+S++ G + + A ++ K ++K D + K ++
Sbjct: 1043 SSQKDEKITGTPR-KAHSKSAKEHQETKPVKEEKVKKDYSKDVKS-------EKLTTKEE 1094
Query: 418 GKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHK 477
++ + +G K K K KG + K KL+ T V P K K +
Sbjct: 1095 KAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSP---KRKME 1151
Query: 478 EEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIA 537
+ + +R K + K KL + K + + E + +E +++ +
Sbjct: 1152 PDTEKMDRTPEKDKISLSAPAKKIKL------NRETGKKIGSTENISNTKEPSEKLESTS 1205
Query: 538 SDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQE----FRSIFDHIKLP 593
S + +VK K+ ++L +ST V+K +E R++ IK
Sbjct: 1206 SKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTV---IKTM 1262
Query: 594 QASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRI 653
+ + + + + ++ ++ + ++ K + E K+T+ S+ K + + +
Sbjct: 1263 EEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDV----KSTQPISSVGKPASVIKNV 1318
Query: 654 DISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKG-- 711
PS + K+ E E+ QK K + + ++H++ + S E+G +K
Sbjct: 1319 STKPSNIVKYPEKESEP---SEKIQKFTKDVSHEI--IQHEVKSSKNSASSEKGKTKDRD 1373
Query: 712 ----SRESSGSRKQEKTPK---------DYKEYKSYKDDSKHKREQDHSRSSSSSASPSS 758
+E+ RK P+ + +KS SK R D S+ +S++
Sbjct: 1374 YSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDF 1433
Query: 759 PSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTF 818
+R++K RE + K ++R + + ++D K R
Sbjct: 1434 TPNRDKKTDYDTREYSSSKRRDEKN-----ELTRRKDSPSRNKDSASGQKNKPREERDLP 1488
Query: 819 QRGRGRFNFKKSGSSP---KWTHD-KYQGDGIVEDEEETMENNEEKKDRRKEEKE 869
++G G + KKS SSP + HD K D +EE + KDR K E
Sbjct: 1489 KKGTG--DSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLE 1541
Score = 76.3 bits (186), Expect = 1e-13
Identities = 147/749 (19%), Positives = 295/749 (39%), Gaps = 110/749 (14%)
Query: 101 RSPRRG----RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSP--------- 147
RSPR +++ +PK + +S S S++ + + +PR + S+S+
Sbjct: 1017 RSPRSEPPIKKAKEETPK---TDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKE 1073
Query: 148 ------YSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFN 201
YSK S++ ++E++ KK ++ PL +K ++ + T E + +D+
Sbjct: 1074 EKVKKDYSKDVKSEKLTTKEEKAKKPN---EKNKPLDNKGEKRKRKTEE----KGVDKDF 1126
Query: 202 KSSATSGDIWPGLSAYDNSPR---SPHSPSPIATPPSQSSSCSDAPM------------L 246
+SS+ SP+ P + TP S S AP +
Sbjct: 1127 ESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLS-APAKKIKLNRETGKKI 1185
Query: 247 STVHSAKNT--PSQHSHS---------IQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPS 295
+ + NT PS+ S ++ R +G+ G+ S+ + S P
Sbjct: 1186 GSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPV 1245
Query: 296 RRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRD 355
R+S KT D R + + TA + +S+ + D
Sbjct: 1246 RKSEEKT--------DTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSK------WDKDD 1291
Query: 356 KEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLA 415
E+ +E + + S K S K+ + E +E +E ++F K V
Sbjct: 1292 FESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKE---SEPSEKIQKFTKDVSH 1348
Query: 416 D-------QGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNY-KLKETGYVVE 467
+ K+ A++ T++ K + + + S +E N +L E G
Sbjct: 1349 EIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKS 1408
Query: 468 RPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFRE 527
++K+ + +S R + K+ K++ D +YS K D + + T R+
Sbjct: 1409 LSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDY--DTREYSSS--KRRDEKNELTRRK 1464
Query: 528 ESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIF 587
+SP R K AS P ++ + P T D +++ +K + ++ +
Sbjct: 1465 DSPSRNKDSASGQKNK---------PREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATY 1515
Query: 588 DHIKLPQASKSTSESFIQ----HIVSLVHHVKEQYFKSAAMTLNERFTSYQK----ATEE 639
D + + +KS ++ + H++ ++ KE LN T +K +
Sbjct: 1516 DTKRPNEETKSVDKNPCKDREKHVLEARNN-KESSGNKLLYILNPPETQVEKEQITGQID 1574
Query: 640 HSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCD--SADLRHDIDR 697
ST + P++ +S S L + T A E + E + + + ++ + S ++ D+
Sbjct: 1575 KSTVKPKPQLSHSSRLS-SDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKD 1633
Query: 698 RRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPS 757
+ E++KE D+ + SR Q + +S+ R S SSS+S++ S
Sbjct: 1634 KIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTR----SHSSSASSAES 1689
Query: 758 SPSSREEKESKKEREEEFKTHHEMKEYSG 786
S +++K+ +K++ ++ K H + K+++G
Sbjct: 1690 QDSKKKKKKKEKKKHKKHKKHKKHKKHAG 1718
Score = 63.9 bits (154), Expect = 6e-10
Identities = 153/715 (21%), Positives = 259/715 (36%), Gaps = 123/715 (17%)
Query: 97 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 156
+ S+SP G S SRS S + +SRS S RS SRS S SRS YS+SP R
Sbjct: 649 KEESKSPYSGSSYSRS----SYTYSKSRSGSTRSRSYSRSFSRSHSRS---YSRSPPYPR 701
Query: 157 RGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSA 216
RG + + ++ + +S+S+ P + H S S F S ++ G +
Sbjct: 702 RGRGKSRNYRSRS--RSHGYHRSRSRSPPYRRY-HSRSRSPQAFRGQSPNKRNVPQGETE 758
Query: 217 YDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVG 276
+ R P P S K + + E+ G
Sbjct: 759 REYFNRYREVPPPYDMKAYYGRSVDFRDPFE-----KERYREWERKYREWYEKYYKGYAA 813
Query: 277 NGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLK 336
R PS N + P R P +N+P +RGR Y G + G
Sbjct: 814 GAQPR--PSANRE-NFSPERFLPLNI---RNSP--FTRGRREDYVGGQSHRSRNIG---- 861
Query: 337 RFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSE 396
++ ++ D N +D SKEK SE +G+ + K ++K +SE
Sbjct: 862 --SNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHK-------KHRKRRKGEESE 912
Query: 397 GD-DTEETEDYRQFRKSVLADQGKS---FATASHRNT--------EEEGLKYKSKVSLKG 444
G + E E R+ R+ ++ K+ F S + + E + +KS VS K
Sbjct: 913 GFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKS-VSEKD 971
Query: 445 NRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLK 504
RE D +P DK K ++ S ++ K+ P + EK
Sbjct: 972 KRERD------------------KPKAKGDKTKRKNDGS-AVSKKENIVKPAKGPQEK-- 1010
Query: 505 DLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLT 564
+D + + R E P++ K K D++ +S
Sbjct: 1011 ------------VDGERERSPRSEPPIK-------------KAKEETPKTDNTKSSSSSQ 1045
Query: 565 KDRLLAST--LVH--SVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFK 620
KD + T H S K+ QE + P + + + + + S KE+ K
Sbjct: 1046 KDEKITGTPRKAHSKSAKEHQETK--------PVKEEKVKKDYSKDVKSEKLTTKEEKAK 1097
Query: 621 SAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRK----HTRLAGEERVFKEE 676
NE+ E+ + + + + + S + K +R + +
Sbjct: 1098 KP----NEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPD 1153
Query: 677 NQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQ--EKTPKDYKEYKSY 734
+K D+ D L ++ + ++E G GS E+ + K+ EK + K
Sbjct: 1154 TEKMDRTPEKDKISL--SAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQE 1211
Query: 735 KDDSKHKREQDHSRSSSSS----ASPSSPSSREEKESKKEREEEFKTHHEMKEYS 785
K K +R+ + SSS+ S SS ++S+++ + + M+EY+
Sbjct: 1212 KVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYN 1266
Score = 47.0 bits (110), Expect = 8e-05
Identities = 82/434 (18%), Positives = 168/434 (38%), Gaps = 60/434 (13%)
Query: 94 VWNRRHSRSPRRGRSRSR--------SPKRRSVSSQRSRSRS-----RRSYRSSRSPRSS 140
V + ++S S +G+++ R +P++R S+Q + + + S S S
Sbjct: 1355 VKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSK 1414
Query: 141 SSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEF 200
+R+S + + S + + KK + + +E S K + ++ + PS
Sbjct: 1415 EARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSR----- 1469
Query: 201 NKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNT----- 255
NK SA S N PR T S+ S+ S + H K T
Sbjct: 1470 NKDSA---------SGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKP-HDHKATYDTKR 1519
Query: 256 PSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRG 315
P++ + S+ +P + V + S N ++ + +P +T +++ G
Sbjct: 1520 PNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYIL----NPPET----QVEKEQITG 1571
Query: 316 ---RSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGE 372
+S+ P +++ L R TDE + + ++ + KE+ S G +
Sbjct: 1572 QIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESS-GNISKD 1630
Query: 373 WEDQ------EALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASH 426
+D+ E+LD + + G + + + S Q +S ++++
Sbjct: 1631 LKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSH-----SPSGSQTRSHSSSAS 1685
Query: 427 RNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERI 486
++ K K K K +++ ++ K K G VE + K KHK++ +
Sbjct: 1686 SAESQDSKKKKKKKEKKKHKKHKKHKKHK----KHAGTEVELEKSQKHKHKKKKSKKNKD 1741
Query: 487 TVKKETQSPEQVKS 500
K++ + ++VKS
Sbjct: 1742 KEKEKEKDDQKVKS 1755
Score = 40.0 bits (92), Expect = 0.009
Identities = 114/639 (17%), Positives = 224/639 (35%), Gaps = 83/639 (12%)
Query: 132 RSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEH 191
+ R+P S+P K +++ G + T+ + L+S S + ++ +
Sbjct: 1156 KMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKG 1215
Query: 192 DPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHS 251
+ SS+T D + S SP+ ++ + ++
Sbjct: 1216 KVRRKVTGTEGSSST---------LVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYN 1266
Query: 252 AKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIA--PQNAP 309
NT I +S S PI + S K ++ P N
Sbjct: 1267 NDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIV 1326
Query: 310 RDESRGRSSFYPDGGDQETAKTGKFLKRFTDE--------ESRVFLLDRGNTRDKEAS-- 359
+ YP+ + + K KF K + E ++G T+D++ S
Sbjct: 1327 K---------YPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVL 1377
Query: 360 KEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGK 419
+++ EK + + E + LD +++ + K S+ T + D S A K
Sbjct: 1378 EKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHD------STRASSNK 1431
Query: 420 SFATASHRNTEEEGLKYKS-------------KVSLKGNRESDGF-----REEKNYKLKE 461
F + T+ + +Y S K S N++S REE++ K
Sbjct: 1432 DFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKG 1491
Query: 462 TGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDARE 521
TG + S+ K D + T K+ + + V KD + L+AR
Sbjct: 1492 TGDSKKSNSSPSRDRKPHDHKATYDT-KRPNEETKSVDKNPCKDREKHV------LEARN 1544
Query: 522 KSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQ 581
+E S ++ I + PE +++ + ++ K +L S+ + S +
Sbjct: 1545 N---KESSGNKLLYILNP---PETQVEKEQIT-GQIDKSTVKPKPQLSHSSRLSSDLTRE 1597
Query: 582 EFRSIFDHIKLPQASKSTSESFI-----QHIVSLVHHVKEQYFKSAAMTLNERFTSYQKA 636
+ F+ P ++S SES + + ++ +K++ + A +L+
Sbjct: 1598 TDEAAFE----PDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGI 1653
Query: 637 TEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGE------ERVFKEENQKGDKKLRCDSAD 690
+ S S R S S R H+ A ++ K++ +K KK +
Sbjct: 1654 SRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKH 1713
Query: 691 LRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYK 729
+H E+S++ K + + +++EK D K
Sbjct: 1714 KKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQK 1752
Score = 34.7 bits (78), Expect = 0.39
Identities = 78/417 (18%), Positives = 136/417 (32%), Gaps = 49/417 (11%)
Query: 7 RSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSR--DYRRDYRNNRG 64
+ + + K+ +Q S + + ++S S++ +R+ D+ S +D+ NR
Sbjct: 1379 KENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRD 1438
Query: 65 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSR 124
+ Y R RR ++ R S S + S S Q+++
Sbjct: 1439 KKTDYDTREYSSS------------------KRRDEKNELTRRKDSPSRNKDSASGQKNK 1480
Query: 125 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEE 184
R R + S S SS + P + K+ P EE+ KS +
Sbjct: 1481 PREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKR-------PNEET--KSVDKNP 1531
Query: 185 PKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAP 244
KD +H + E + +SG+ Y +P T S+ P
Sbjct: 1532 CKDREKH-----VLEARNNKESSGN----KLLYILNPPETQVEKEQITGQIDKSTVKPKP 1582
Query: 245 MLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGN-------GSSRYSPSQNSPIHHIPSRR 297
LS + ++ + P+ + S S N S S I
Sbjct: 1583 QLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKES 1642
Query: 298 SPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLD-RGNTRDK 356
+ R++S S P + + +G + + S D + + K
Sbjct: 1643 LDTAAVVQVGISRNQSHSSPSVSPS---RSHSPSGSQTRSHSSSASSAESQDSKKKKKKK 1699
Query: 357 EASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSV 413
E K K +K + + E S K K+K + D +E E Q KSV
Sbjct: 1700 EKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSV 1756
Score = 30.8 bits (68), Expect = 5.7
Identities = 17/65 (26%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Query: 1 MGRSNSRSHSSRS--KSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRD 58
+G S ++SHSS S SRS S S S++RSHS + + + +++ + +++
Sbjct: 1651 VGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKH 1710
Query: 59 YRNNR 63
++ +
Sbjct: 1711 KKHKK 1715
Score = 30.0 bits (66), Expect = 9.7
Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 10/101 (9%)
Query: 511 PPLHKNLDAREKSTF-REESPLRIKMIASDSH-RPEVKLKMA-------PVPLDDSNRPA 561
P + +NL +S R++ PL I + +S +H P + + PV + S+ PA
Sbjct: 348 PLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQSSLAPPVSGNPSSAPA 407
Query: 562 SLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSES 602
+ S VHS K + FR D+ LP A+ ++ S
Sbjct: 408 PVPDITATVSISVHSEKSDGPFRD-SDNKILPAAALASEHS 447
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 84.0 bits (206), Expect = 6e-16
Identities = 167/741 (22%), Positives = 274/741 (36%), Gaps = 94/741 (12%)
Query: 97 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPR-SSSSRSSSP----YSKS 151
R SRSPRR +SRS SP+RRS +R R RS SRSPR + SRS SP K+
Sbjct: 166 RERSRSPRRRKSRSPSPRRRSSPVRRERKRSH-----SRSPRHRTKSRSPSPAPEKKEKT 220
Query: 152 P------VSKRRGSQEKQTKKAE----------GEPQEESPLKSKSQEEPKDTFEHDPSE 195
P V + S ++ T ++ EP+E SP K+ +E+ K E
Sbjct: 221 PELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEK--------E 272
Query: 196 SIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNT 255
++S + S S PR H + P + S P +
Sbjct: 273 KTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRM 332
Query: 256 PSQHSHSIQHSP----ERSGSGSVGNGSSRYSPSQNSPIHHIPSRRS--PAKT--IAPQN 307
P H SP RS + G+ SS S SP P R S P KT ++P
Sbjct: 333 PPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSA 392
Query: 308 APRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKG 367
+P R R S P +T + + +SRV + G T K +K KG+EK
Sbjct: 393 SP-PRRRHRPS-PPATPPPKTRHSPTPQQSNRTRKSRV-SVSPGRTSGK-VTKHKGTEKR 448
Query: 368 RAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFAT---- 423
+ ++ +E K + D ++ YR+ + +D G S ++
Sbjct: 449 ESPSPAPKPRKVELSESEEDKGGKM--AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDER 506
Query: 424 --ASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEE-- 479
SH E G + + S R + ++ + G PS + +
Sbjct: 507 PKRSHVKNGEVGRRRRHSPS----RSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPS 562
Query: 480 ----DKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREES-PLRIK 534
+ T ++P + YSPP+ + R S P K
Sbjct: 563 PAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPK 622
Query: 535 MIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQ 594
AS S P+ ++ +P P R + +TK R + + H K RS + + PQ
Sbjct: 623 RRASPSPPPKRRVSHSPPP---KQRSSPVTKRRSPSLSSKHR-KGSSPSRSTRE-ARSPQ 677
Query: 595 ASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRID 654
+K S S + A + +R S +T ++PE ++I
Sbjct: 678 PNKRHSPSPRPRAPQT--SSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPE-PKKIK 734
Query: 655 ISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHD-----------IDRRRKERS 703
+ S + R R + KK + ++ + + +
Sbjct: 735 KAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTP 794
Query: 704 KERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPS--- 760
+E G +K++K K +K+ K +K KHK+E+ + +++++ +P++ +
Sbjct: 795 SPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAAT 854
Query: 761 ---SREE----KESKKEREEE 774
++EE E KKE E E
Sbjct: 855 TTLAQEEPVAAPEPKKETESE 875
Score = 73.6 bits (179), Expect = 8e-13
Identities = 83/316 (26%), Positives = 121/316 (38%), Gaps = 45/316 (14%)
Query: 18 QSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRGRGRG 77
+ S S+ K++ R RSR+ S+SRSR R S + R R +R R Y R R
Sbjct: 258 EPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRR--- 314
Query: 78 YYQGGGGRYHRGGYRPVWNRRHSRSPRRGRS-RSRSPKRR---SVSSQRSRSRSRRSYRS 133
SPRR S R R+P RR +RSRS RR RS
Sbjct: 315 -----------------------PSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRS 351
Query: 134 SRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDT----F 189
S S SSS SSS S+SP K +K SP + + + P T
Sbjct: 352 SASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKT 411
Query: 190 EHDPSESIDEFNKSSATSGDIWPGLSA----YDNSPRSPHSPSPIATPPSQSSSCSDAPM 245
H P+ + N++ + + PG ++ SPSP P S S+
Sbjct: 412 RHSPTP--QQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDK 469
Query: 246 LSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRR--SPAKTI 303
+ +A + + + Q+ S SGS + + + RR SP+++
Sbjct: 470 GGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSA 529
Query: 304 APQNAPRDES---RGR 316
+P R + RGR
Sbjct: 530 SPSPRKRQKETSPRGR 545
Score = 57.8 bits (138), Expect = 4e-08
Identities = 88/330 (26%), Positives = 118/330 (35%), Gaps = 37/330 (11%)
Query: 8 SHSSRSKSRSQSSSRS-RSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMR 66
S S K +++ S + R R++ +S S + S S S D R + ++ R R
Sbjct: 463 SESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRR 522
Query: 67 ----RPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQR 122
R R R GR R P RR S SP R R+P R
Sbjct: 523 HSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTP----TPPPR 578
Query: 123 SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQ 182
R+ S R S SPR S YS SP KRR + K P SP
Sbjct: 579 RRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASP---SP------ 629
Query: 183 EEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSD 242
PK H P +SS + P LS+ SP S+S+ +
Sbjct: 630 -PPKRRVSHSPPPK----QRSSPVTKRRSPSLSSKHRKGSSP----------SRSTREAR 674
Query: 243 APMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNS-PIHHIPSRRSPAK 301
+P + HS P S P R G+ S + R SPS ++ PI + P K
Sbjct: 675 SPQPNKRHSPSPRPRAPQTSSSPPPVRRGASS--SPQRRQSPSPSTRPIRRVSRTPEPKK 732
Query: 302 -TIAPQNAPRDESRGRSSFYPDGGDQETAK 330
A +P+ R SS G + AK
Sbjct: 733 IKKAASPSPQSVRRVSSSRSVSGSPEPAAK 762
Score = 53.1 bits (126), Expect = 1e-06
Identities = 79/280 (28%), Positives = 111/280 (39%), Gaps = 36/280 (12%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNR 63
S S S S R + + S R RS S R RS + + R R + RR +
Sbjct: 526 SRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPP 585
Query: 64 GMRRPYGYRGRG----RGYYQGGGGRYHRGGYRPVWNRRHSRSP--RRGRSRSRSPKRRS 117
RR R R Y + P RR S SP +R S S PK+RS
Sbjct: 586 PRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRS 645
Query: 118 --VSSQRSRSRSR---------RSYRSSRSPRSSSSRSSSPY------SKSPVSKRRGSQ 160
V+ +RS S S RS R +RSP+ + S SP S SP RRG+
Sbjct: 646 SPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGAS 705
Query: 161 EKQTKKAEGEPQEESPLK--SKSQEEPKDTFEHDPS-ESIDEFNKSSATSGDIWPGLSAY 217
++ P P++ S++ E K PS +S+ + S + SG P
Sbjct: 706 SSPQRRQSPSPSTR-PIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPA---- 760
Query: 218 DNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS 257
+ + P PSP+ SQS S + +P + + TPS
Sbjct: 761 --AKKPPAPPSPV---QSQSPSTNWSPAVPVKKAKSPTPS 795
Score = 52.0 bits (123), Expect = 2e-06
Identities = 83/378 (21%), Positives = 132/378 (34%), Gaps = 45/378 (11%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
R SRS S R RS R R RSHSR R+R++SR+ S + + +
Sbjct: 174 RRKSRSPSPRR--RSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVK-- 229
Query: 63 RGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQR 122
++ P P+ + + + K R S R
Sbjct: 230 --VKEPSVQEATSTSDI------LKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSR 281
Query: 123 SRSRSRRSYRS-----SRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEP-----Q 172
S+SRSR RS R S SRS SP + P +RR S ++T P +
Sbjct: 282 SKSRSRTRSRSPSHTRPRRRHRSRSRSYSP-RRRPSPRRRPSPRRRTPPRRMPPPPRHRR 340
Query: 173 EESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIAT 232
SP++ + + S S+ + SS++S P P+ P P ++
Sbjct: 341 SRSPVRRRRRS----------SASLSGSSSSSSSSRSRSP--------PKKP--PKRTSS 380
Query: 233 PPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHH 292
PP ++ S + + P+ +HSP S SP + S
Sbjct: 381 PPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTS--GK 438
Query: 293 IPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGN 352
+ + K +P AP+ S D G + A +R +++ D G+
Sbjct: 439 VTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGS 498
Query: 353 TRDKEASKEKGSEKGRAE 370
+ E + K S E
Sbjct: 499 SSSSEDERPKRSHVKNGE 516
Score = 37.4 bits (85), Expect = 0.061
Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 11/121 (9%)
Query: 654 DISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLR------HDIDRRRKERSKERG 707
++ P L +AG F E ++ K+ + + L D D+R KE KE
Sbjct: 104 ELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEE-KESS 162
Query: 708 DSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES 767
K R S R++ ++P + + +R++ HSRS SPS EK+
Sbjct: 163 REKRERSRSPRRRKSRSPSPRRR----SSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKE 218
Query: 768 K 768
K
Sbjct: 219 K 219
Score = 35.4 bits (80), Expect = 0.23
Identities = 49/205 (23%), Positives = 75/205 (36%), Gaps = 25/205 (12%)
Query: 599 TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPS 658
+++ I I S +K++ K + E+ S +K E+ R K + S
Sbjct: 111 SAQENIAGIPSAFLELKKEEIKQRQIE-QEKLASMKKQDEDKDKRDKEEK--------ES 161
Query: 659 TLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGD---SKGSRES 715
+ K R R +K R S R RR ++RS R +K S
Sbjct: 162 SREKRERSRSPRR----------RKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPS 211
Query: 716 SGSRKQEKTPKDYKEYKSYKDDSKHKREQ--DHSRSSSSSASPSSPSSREEKESKKEREE 773
K+EKTP+ + K+ S + D + P EK SKKE+E+
Sbjct: 212 PAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEK 271
Query: 774 EFKTHHEMKEYSGFAGVSRPRGTFH 798
E KT + S +R R H
Sbjct: 272 E-KTRPRSRSRSKSRSRTRSRSPSH 295
Score = 33.9 bits (76), Expect = 0.67
Identities = 69/310 (22%), Positives = 104/310 (33%), Gaps = 30/310 (9%)
Query: 486 ITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEV 545
+ +KKE Q++ EKL + K D EK + RE+ S P
Sbjct: 124 LELKKEEIKQRQIEQEKLASMKKQDEDKDKR-DKEEKESSREKRERSRSPRRRKSRSPSP 182
Query: 546 KLKMAPVPLD----DSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSE 601
+ + +PV + S P TK R S +K E +K P ++TS
Sbjct: 183 RRRSSPVRRERKRSHSRSPRHRTKSRS-PSPAPEKKEKTPELPEPSVKVKEPSVQEATST 241
Query: 602 SFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLR 661
S I + + E K + N + ++ T S R +S R SPS R
Sbjct: 242 SDILKVPK-PEPIPEP--KEPSPEKNSKKEKEKEKTRPRS-RSRSKSRSRTRSRSPSHTR 297
Query: 662 KHTRLAGEERVFKEENQKGDKKL---------RCDSADLRHDIDR----RRKERSKERGD 708
R R + + ++ R RH R RR+ S
Sbjct: 298 PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSG 357
Query: 709 SKGSRESSGSRKQEKTPKDYKEYKSYK----DDSKHKREQDHSRSSSSSASPS---SPSS 761
S S SS SR K P K S + H S ++ P SP+
Sbjct: 358 SSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTP 417
Query: 762 REEKESKKER 771
++ ++K R
Sbjct: 418 QQSNRTRKSR 427
Score = 32.0 bits (71), Expect = 2.6
Identities = 71/332 (21%), Positives = 107/332 (32%), Gaps = 80/332 (24%)
Query: 466 VERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTF 525
+++ KDK +E+K S R ++ ++SP + KS SP + RE+
Sbjct: 144 MKKQDEDKDKRDKEEKESSR-EKRERSRSPRRRKSRSP------SPRRRSSPVRRERKRS 196
Query: 526 REESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRS 585
SP S S PE K K +P P+ K+ QE S
Sbjct: 197 HSRSPRHRTKSRSPSPAPEKKEKTPELP-----EPSVKVKE-----------PSVQEATS 240
Query: 586 IFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQK 645
D +K+P+ + + E++S ++K
Sbjct: 241 TSDILKVPKPEPIPEPK-------------------------------EPSPEKNSKKEK 269
Query: 646 SPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKE 705
E R S S R TR S H RRR RS+
Sbjct: 270 EKEKTRPRSRSRSKSRSRTR----------------------SRSPSHTRPRRR-HRSRS 306
Query: 706 RGDSKGSRESSGSR---KQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSR 762
R S R S R ++ P+ ++ R + S +S S +S SS SSR
Sbjct: 307 RSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSR 366
Query: 763 EEKESKKEREEEFKTHHEMKEYSGFAGVSRPR 794
KK + + + S A R R
Sbjct: 367 SRSPPKKPPKRTSSPPRKTRRLSPSASPPRRR 398
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 81.6 bits (200), Expect = 3e-15
Identities = 87/332 (26%), Positives = 133/332 (40%), Gaps = 50/332 (15%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRN 61
G+SN R RS+S ++S SRS S+SHSR+KR +S+ R+ S +RSR R ++
Sbjct: 298 GKSNERK-GGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQ---------KD 347
Query: 62 NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 121
R + P+ R + R R +R HSR R+ K R
Sbjct: 348 RRRSKSPHKKRSKSR-------------ERRKSRSRSHSRDKRKDTREKIKEKERVKEKD 394
Query: 122 RSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKS 181
R + R R R R + K + +E++ +K + +++ K K
Sbjct: 395 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE--KEKE 452
Query: 182 QEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCS 241
Q++ K+ E D S+ IDE K S P S Y+ S RS S S+SSS S
Sbjct: 453 QDKEKER-EKDRSKEIDEKRKKDKKSRT--PPRS-YNASRRSRSSSRERRRRRSRSSSRS 508
Query: 242 DAPMLSTVHSAKNTPSQHSHS------------IQHSPERSGSGSVGNGSS--------- 280
+ + +PS S + I ER S S+ S+
Sbjct: 509 PRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLE 568
Query: 281 RYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDE 312
+ S S H+ S +K + ++APR E
Sbjct: 569 KNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 600
Score = 54.7 bits (130), Expect = 4e-07
Identities = 76/367 (20%), Positives = 135/367 (36%), Gaps = 42/367 (11%)
Query: 213 GLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS 272
G+ D + HS + I PP + + + + + S S +I+ PE S
Sbjct: 243 GVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIE--PESGKS 300
Query: 273 GSVGNGSSRY---SPSQNSPIHHIPSRRSPAKTIA-----PQNAPRDESRGRSSFYPDGG 324
G SR S S++S H +RS +K + ++ +D R +S
Sbjct: 301 NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 360
Query: 325 DQETAKTG---------KFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWED 375
+E K+ K + E+ RV DR R++E +EK E+G+ + ++
Sbjct: 361 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 420
Query: 376 QEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLK 435
+E D+E K+K D E + +E E R K D+ K + +E+ K
Sbjct: 421 RE-----KDREKDKEK--DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK 473
Query: 436 YK-----------SKVSLKGNRESDGFREEKNYKLKETGYVVER-----PSTTKDKHKEE 479
K S+ S +RE R + + T ++R PS K++
Sbjct: 474 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 533
Query: 480 DKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASD 539
+ ER + + + K + D L KN + ++ +E + D
Sbjct: 534 KREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDD 593
Query: 540 SHRPEVK 546
P +
Sbjct: 594 KDAPRTE 600
Score = 50.1 bits (118), Expect = 9e-06
Identities = 51/233 (21%), Positives = 89/233 (38%), Gaps = 5/233 (2%)
Query: 634 QKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRH 693
+ +++ HS R++S HR + S R+ R + K + +K R S
Sbjct: 317 RSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK 376
Query: 694 DIDRRRKERSKER---GDSKGSRESSGSRKQEK-TPKDYKEYKSYKDDSKHKREQDHSRS 749
D R K + KER D + RE R++EK K+ K + D + +E+D R
Sbjct: 377 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE 436
Query: 750 SSSSASPSSPSSRE-EKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYW 808
+E E++ +KERE++ + K + PR R
Sbjct: 437 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRE 496
Query: 809 AKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKK 861
+R R R + + R K+ S + + D E E + + E++
Sbjct: 497 RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERE 549
Score = 49.3 bits (116), Expect = 2e-05
Identities = 74/355 (20%), Positives = 125/355 (35%), Gaps = 42/355 (11%)
Query: 93 PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 152
P + + R R RS +RS R S S R RS+ +RS RS S + SKSP
Sbjct: 295 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 354
Query: 153 VSKRRGSQEKQTKKAEGEPQEE-----SPLKSKSQEEPKDTFEHDPSESIDEFNKSSATS 207
KR S+E++ ++ +++ +K K + + KD + E E K +
Sbjct: 355 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 414
Query: 208 GDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSP 267
D D + ++ + +
Sbjct: 415 KD-------RDKEREKDRE--------KDKEKDREREREKEHEKDRDKEKEKEQDKEKER 459
Query: 268 ERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQE 327
E+ S + + S+ P + SRRS +++ R+ R RS
Sbjct: 460 EKDRSKEIDEKRKKDKKSRTPPRSYNASRRS-------RSSSRERRRRRSR-----SSSR 507
Query: 328 TAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKES 387
+ +T K +KR + SR N +DK+ KE+ R E E ++ S+
Sbjct: 508 SPRTSKTIKR---KSSRSPSPRSRNKKDKKREKERDHISERRER--ERSTSMRKSSNDRD 562
Query: 388 GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSL 442
GK+K + +E E ++ SV K TEE +++ L
Sbjct: 563 GKEKL-EKNSTSLKEKEHNKEPDSSV----SKEVDDKDAPRTEENKIQHNGNCQL 612
Score = 48.9 bits (115), Expect = 2e-05
Identities = 60/267 (22%), Positives = 101/267 (37%), Gaps = 15/267 (5%)
Query: 519 AREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVK 578
+ E+ R S R K +S K + NR S KDR + +
Sbjct: 300 SNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRS 359
Query: 579 KEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATE 638
K +E R K T E + VKE+ + ER +K
Sbjct: 360 KSRERRKSRSRSHSRDKRKDTREKIKEK-----ERVKEKDREKEREREKER--EKEKERG 412
Query: 639 EHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRR 698
++ R K E R D R+ + ++R ++E ++ +K R D +ID +
Sbjct: 413 KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER--EKDRSKEIDEK 470
Query: 699 RKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSS 758
RK+ K R R + SR+ + ++ + +S + + R SS S S
Sbjct: 471 RKKDKKSR---TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS---PS 524
Query: 759 PSSREEKESKKEREEEFKTHHEMKEYS 785
P SR +K+ K+E+E + + +E S
Sbjct: 525 PRSRNKKDKKREKERDHISERRERERS 551
Score = 43.1 bits (100), Expect = 0.001
Identities = 75/368 (20%), Positives = 136/368 (36%), Gaps = 50/368 (13%)
Query: 417 QGKSFATA-----SHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPST 471
+ +SF +A S ++ E +G + +S K S K + K S
Sbjct: 284 EAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSR-----SH 338
Query: 472 TKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPL 531
+ + +++D+ + KK ++S E+ KS D K D REK +E+ +
Sbjct: 339 NRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRD------KRKDTREK--IKEKERV 390
Query: 532 RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIK 591
+ K + R + + K + R + +D+ +K++E +H K
Sbjct: 391 KEKDREKEREREKEREK-------EKERGKNKDRDKEREKDREKDKEKDREREREKEHEK 443
Query: 592 LPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHR 651
K + +++ K + ++E+ +K ++ T +S R
Sbjct: 444 DRDKEKEKEQD-----------KEKEREKDRSKEIDEK----RKKDKKSRTPPRSYNASR 488
Query: 652 RIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKG 711
R S S R+ R R + K R S R+ D K+R KER
Sbjct: 489 R-SRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD---KKREKERDHISE 544
Query: 712 SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER 771
RE S K+ D + + +S +E++H++ P S S+E + R
Sbjct: 545 RRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNK------EPDSSVSKEVDDKDAPR 598
Query: 772 EEEFKTHH 779
EE K H
Sbjct: 599 TEENKIQH 606
Score = 39.7 bits (91), Expect = 0.012
Identities = 54/238 (22%), Positives = 88/238 (36%), Gaps = 44/238 (18%)
Query: 635 KATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHD 694
K EE R + + I P + + + R G R + K
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSH--------- 323
Query: 695 IDRRRKERSKERGDSKG-SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSS 753
RR++ +SK R S SR R++ K+P K +R + SRS S
Sbjct: 324 -SRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK-------KRSKSRERRKSRSRSHSRD 375
Query: 754 ASPSSPSSREEKE--SKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKR 811
+ +EKE +K+RE+E + E ++ + RG + DRD
Sbjct: 376 KRKDTREKIKEKERVKEKDREKEREREKEREK-------EKERGK-NKDRDK-------- 419
Query: 812 GRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 869
+R + R K+ + +++ D E E+E + E +KDR KE E
Sbjct: 420 -------EREKDREKDKEK-DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 469
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 81.6 bits (200), Expect = 3e-15
Identities = 87/332 (26%), Positives = 133/332 (40%), Gaps = 50/332 (15%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRN 61
G+SN R RS+S ++S SRS S+SHSR+KR +S+ R+ S +RSR R ++
Sbjct: 182 GKSNERK-GGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQ---------KD 231
Query: 62 NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 121
R + P+ R + R R +R HSR R+ K R
Sbjct: 232 RRRSKSPHKKRSKSR-------------ERRKSRSRSHSRDKRKDTREKIKEKERVKEKD 278
Query: 122 RSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKS 181
R + R R R R + K + +E++ +K + +++ K K
Sbjct: 279 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE--KEKE 336
Query: 182 QEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCS 241
Q++ K+ E D S+ IDE K S P S Y+ S RS S S+SSS S
Sbjct: 337 QDKEKER-EKDRSKEIDEKRKKDKKSRT--PPRS-YNASRRSRSSSRERRRRRSRSSSRS 392
Query: 242 DAPMLSTVHSAKNTPSQHSHS------------IQHSPERSGSGSVGNGSS--------- 280
+ + +PS S + I ER S S+ S+
Sbjct: 393 PRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLE 452
Query: 281 RYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDE 312
+ S S H+ S +K + ++APR E
Sbjct: 453 KNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 484
Score = 54.7 bits (130), Expect = 4e-07
Identities = 76/367 (20%), Positives = 135/367 (36%), Gaps = 42/367 (11%)
Query: 213 GLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS 272
G+ D + HS + I PP + + + + + S S +I+ PE S
Sbjct: 127 GVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIE--PESGKS 184
Query: 273 GSVGNGSSRY---SPSQNSPIHHIPSRRSPAKTIA-----PQNAPRDESRGRSSFYPDGG 324
G SR S S++S H +RS +K + ++ +D R +S
Sbjct: 185 NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 244
Query: 325 DQETAKTG---------KFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWED 375
+E K+ K + E+ RV DR R++E +EK E+G+ + ++
Sbjct: 245 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 304
Query: 376 QEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLK 435
+E D+E K+K D E + +E E R K D+ K + +E+ K
Sbjct: 305 RE-----KDREKDKEK--DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK 357
Query: 436 YK-----------SKVSLKGNRESDGFREEKNYKLKETGYVVER-----PSTTKDKHKEE 479
K S+ S +RE R + + T ++R PS K++
Sbjct: 358 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 417
Query: 480 DKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASD 539
+ ER + + + K + D L KN + ++ +E + D
Sbjct: 418 KREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDD 477
Query: 540 SHRPEVK 546
P +
Sbjct: 478 KDAPRTE 484
Score = 50.1 bits (118), Expect = 9e-06
Identities = 51/233 (21%), Positives = 89/233 (38%), Gaps = 5/233 (2%)
Query: 634 QKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRH 693
+ +++ HS R++S HR + S R+ R + K + +K R S
Sbjct: 201 RSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK 260
Query: 694 DIDRRRKERSKER---GDSKGSRESSGSRKQEK-TPKDYKEYKSYKDDSKHKREQDHSRS 749
D R K + KER D + RE R++EK K+ K + D + +E+D R
Sbjct: 261 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE 320
Query: 750 SSSSASPSSPSSRE-EKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYW 808
+E E++ +KERE++ + K + PR R
Sbjct: 321 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRE 380
Query: 809 AKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKK 861
+R R R + + R K+ S + + D E E + + E++
Sbjct: 381 RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERE 433
Score = 49.3 bits (116), Expect = 2e-05
Identities = 74/355 (20%), Positives = 125/355 (35%), Gaps = 42/355 (11%)
Query: 93 PVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 152
P + + R R RS +RS R S S R RS+ +RS RS S + SKSP
Sbjct: 179 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 238
Query: 153 VSKRRGSQEKQTKKAEGEPQEE-----SPLKSKSQEEPKDTFEHDPSESIDEFNKSSATS 207
KR S+E++ ++ +++ +K K + + KD + E E K +
Sbjct: 239 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 298
Query: 208 GDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSP 267
D D + ++ + +
Sbjct: 299 KD-------RDKEREKDRE--------KDKEKDREREREKEHEKDRDKEKEKEQDKEKER 343
Query: 268 ERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQE 327
E+ S + + S+ P + SRRS +++ R+ R RS
Sbjct: 344 EKDRSKEIDEKRKKDKKSRTPPRSYNASRRS-------RSSSRERRRRRSR-----SSSR 391
Query: 328 TAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKES 387
+ +T K +KR + SR N +DK+ KE+ R E E ++ S+
Sbjct: 392 SPRTSKTIKR---KSSRSPSPRSRNKKDKKREKERDHISERRER--ERSTSMRKSSNDRD 446
Query: 388 GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSL 442
GK+K + +E E ++ SV K TEE +++ L
Sbjct: 447 GKEKL-EKNSTSLKEKEHNKEPDSSV----SKEVDDKDAPRTEENKIQHNGNCQL 496
Score = 48.9 bits (115), Expect = 2e-05
Identities = 60/267 (22%), Positives = 101/267 (37%), Gaps = 15/267 (5%)
Query: 519 AREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVK 578
+ E+ R S R K +S K + NR S KDR + +
Sbjct: 184 SNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRS 243
Query: 579 KEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATE 638
K +E R K T E + VKE+ + ER +K
Sbjct: 244 KSRERRKSRSRSHSRDKRKDTREKIKEK-----ERVKEKDREKEREREKER--EKEKERG 296
Query: 639 EHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRR 698
++ R K E R D R+ + ++R ++E ++ +K R D +ID +
Sbjct: 297 KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER--EKDRSKEIDEK 354
Query: 699 RKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSS 758
RK+ K R R + SR+ + ++ + +S + + R SS S S
Sbjct: 355 RKKDKKSR---TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS---PS 408
Query: 759 PSSREEKESKKEREEEFKTHHEMKEYS 785
P SR +K+ K+E+E + + +E S
Sbjct: 409 PRSRNKKDKKREKERDHISERRERERS 435
Score = 43.1 bits (100), Expect = 0.001
Identities = 75/368 (20%), Positives = 136/368 (36%), Gaps = 50/368 (13%)
Query: 417 QGKSFATA-----SHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPST 471
+ +SF +A S ++ E +G + +S K S K + K S
Sbjct: 168 EAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSR-----SH 222
Query: 472 TKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPL 531
+ + +++D+ + KK ++S E+ KS D K D REK +E+ +
Sbjct: 223 NRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRD------KRKDTREK--IKEKERV 274
Query: 532 RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIK 591
+ K + R + + K + R + +D+ +K++E +H K
Sbjct: 275 KEKDREKEREREKEREK-------EKERGKNKDRDKEREKDREKDKEKDREREREKEHEK 327
Query: 592 LPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHR 651
K + +++ K + ++E+ +K ++ T +S R
Sbjct: 328 DRDKEKEKEQD-----------KEKEREKDRSKEIDEK----RKKDKKSRTPPRSYNASR 372
Query: 652 RIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKG 711
R S S R+ R R + K R S R+ D K+R KER
Sbjct: 373 R-SRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD---KKREKERDHISE 428
Query: 712 SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKER 771
RE S K+ D + + +S +E++H++ P S S+E + R
Sbjct: 429 RRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNK------EPDSSVSKEVDDKDAPR 482
Query: 772 EEEFKTHH 779
EE K H
Sbjct: 483 TEENKIQH 490
Score = 39.7 bits (91), Expect = 0.012
Identities = 54/238 (22%), Positives = 88/238 (36%), Gaps = 44/238 (18%)
Query: 635 KATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHD 694
K EE R + + I P + + + R G R + K
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSH--------- 207
Query: 695 IDRRRKERSKERGDSKG-SRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSS 753
RR++ +SK R S SR R++ K+P K +R + SRS S
Sbjct: 208 -SRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK-------KRSKSRERRKSRSRSHSRD 259
Query: 754 ASPSSPSSREEKE--SKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKR 811
+ +EKE +K+RE+E + E ++ + RG + DRD
Sbjct: 260 KRKDTREKIKEKERVKEKDREKEREREKEREK-------EKERGK-NKDRDK-------- 303
Query: 812 GRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 869
+R + R K+ + +++ D E E+E + E +KDR KE E
Sbjct: 304 -------EREKDREKDKEK-DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 353
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 81.3 bits (199), Expect = 4e-15
Identities = 71/202 (35%), Positives = 88/202 (43%), Gaps = 40/202 (19%)
Query: 1 MGRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR 60
MGR SR + RS SR +S SRSRSRS S K+ R R SRSR RDR R RD R
Sbjct: 1 MGRE-SRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRR-SRSRDRDRRRERSRSRDKR 58
Query: 61 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSS 120
+R R R R R R R R RSRS RR
Sbjct: 59 RSRSRDRKRLRRSRSR-----------------------ERDRSRERRRSRSRDRR---R 92
Query: 121 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSK 180
RSRSR RR SRSSSP +KS ++ R +++T E +++ K
Sbjct: 93 SRSRSRGRR------------SRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDK 140
Query: 181 SQEEPKDTFEHDPSESIDEFNK 202
E+ KD D ++ +E K
Sbjct: 141 EDEKEKDAGNFDQNKLEEEMRK 162
Score = 63.9 bits (154), Expect = 6e-10
Identities = 59/203 (29%), Positives = 81/203 (39%), Gaps = 25/203 (12%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
RS SR R + RS+S + RSRS RK+ RSRSR RSR R R SRD RR +
Sbjct: 39 RSRSRDRDRR-RERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRS 97
Query: 63 RGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQR 122
RG R G + NR S+ G S+ K+ +
Sbjct: 98 RGRRSRSSSPGNKS---------------KKTENRSRSKEKTDGGESSKEKKKDKDDKED 142
Query: 123 SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQ---EESPLKS 179
+ + ++ ++ R K V K R Q K+ + GE + EE
Sbjct: 143 EKEKDAGNFDQNKLEEEMRKR------KERVEKWREEQRKKAMENIGELKKEIEEMKQGK 196
Query: 180 KSQEEPKDTFEHDPSESIDEFNK 202
K E D E DP+E+ E N+
Sbjct: 197 KWSLEDDDDDEDDPAEAEKEGNE 219
Score = 48.1 bits (113), Expect = 3e-05
Identities = 45/192 (23%), Positives = 81/192 (42%), Gaps = 21/192 (10%)
Query: 629 RFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDK---KLR 685
R S +++ R +S + RR + S S ++ +R +R+ + +++ D+ + R
Sbjct: 25 RSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRR 84
Query: 686 CDSADLRHDIDRRRKERSKERGDSKGSRESSG-SRKQEKTP--KDYKEYKSYKDDSKHKR 742
S D R R R RS+ S+++ SR +EKT + KE K KDD + ++
Sbjct: 85 SRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEK 144
Query: 743 EQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSR--------PR 794
E+D + EE +KER E+++ K + + +
Sbjct: 145 EKDAGNFDQNKL-------EEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKK 197
Query: 795 GTFHDDRDDGVD 806
+ DD DD D
Sbjct: 198 WSLEDDDDDEDD 209
Score = 43.5 bits (101), Expect = 8e-04
Identities = 43/213 (20%), Positives = 85/213 (39%), Gaps = 15/213 (7%)
Query: 656 SPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKER-GDSKGSRE 714
SPS K ++ + R + + ++ R DR+R RS+ R D R
Sbjct: 26 SPSD--KRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERR 83
Query: 715 SSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEE 774
S SR + ++ + +S +K ++ +RS S + SS+E+K+ K ++E+E
Sbjct: 84 RSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDE 143
Query: 775 FKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSP 834
+ + + R R + V+ W + R + G + ++
Sbjct: 144 KEKDAGNFDQNKLEEEMR-------KRKERVEKWREEQRKKAMENIGELKKEIEEMKQGK 196
Query: 835 KWTHDKYQGDGIVEDEEETMENNEEKKDRRKEE 867
KW+ + +DE++ E +E + EE
Sbjct: 197 KWSLEDDD-----DDEDDPAEAEKEGNEMEGEE 224
Score = 35.8 bits (81), Expect = 0.18
Identities = 67/313 (21%), Positives = 117/313 (37%), Gaps = 67/313 (21%)
Query: 295 SRRSPAKTIAPQN-APRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNT 353
SR +++ +P N + + E+R RS DGG+ K K+ D++ D GN
Sbjct: 97 SRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEK-----KKDKDDKEDEKEKDAGNF 151
Query: 354 RDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSV 413
+ +E K R E +W +++ ++K ++ G+ +E E+ +Q +K
Sbjct: 152 DQNKLEEEMRKRKERVE-KWREEQ-----------RKKAMENIGELKKEIEEMKQGKKWS 199
Query: 414 LADQGKSF---ATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPS 470
L D A A E EG + D + EE ++K+
Sbjct: 200 LEDDDDDEDDPAEAEKEGNEMEGEELD---------PLDAYMEEVKEEVKKFNM-----R 245
Query: 471 TTKDKHKEEDKNSERIT--VKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREE 528
+ K E K+ +T V T V S+K K + + DA E S+ EE
Sbjct: 246 SVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKK-----GELMENDQDAMEYSSEEEE 300
Query: 529 SPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFD 588
L+ + TK R L + H + + FR F
Sbjct: 301 VDLQTALTGYQ------------------------TKQRKLLEPVDHGKIEYEPFRKNF- 335
Query: 589 HIKLPQASKSTSE 601
++++P+ +K + E
Sbjct: 336 YVEVPELAKMSQE 348
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 80.1 bits (196), Expect = 8e-15
Identities = 191/839 (22%), Positives = 315/839 (37%), Gaps = 138/839 (16%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNR 63
S+ ++S S S+SS RSRSRS SRSR+YSRS +R R + + R
Sbjct: 673 SDQSTYSKYSDRSSESSPRSRSRS--------SRSRSYSRSYTRSRSLASSHSRS----- 719
Query: 64 GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRS 123
R R R Y Y + + R+ RR RS S K+ SVS ++
Sbjct: 720 ---RSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRS---SGKKNSVSHKKH 773
Query: 124 RSRSRRSY---------RSSRSPRSSSSRSSSPYSK-SPVSKRRGSQEKQTKKAEGEPQE 173
S S ++ RSS + S SRSS YS S S + +Q Q K+ +G+ +
Sbjct: 774 SSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMER 833
Query: 174 ESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATP 233
+ K++ E K E + S K ++ L R ++ S
Sbjct: 834 THNKQEKNRGEEKSKSERECPHS-----KKRTLKENLSDHLRNGSKPKRKNYAGSKW--- 885
Query: 234 PSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIH-- 291
S+S+S D ++KN H S + E + S S+ S IH
Sbjct: 886 DSESNSERD-----VTKNSKN--DSHPSSDKEEGEATSD----------SESEVSEIHIK 928
Query: 292 HIPSRRSPAKTIAP-QNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDR 350
P+ +S T P N S+ R+S G ++ + + S+ L
Sbjct: 929 VKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKRE 988
Query: 351 GNTRDKEASKEKGSEKGRAE--------------GEWEDQEALDYFSDKESGKQKFNDSE 396
+ KE K K +K +A GE E++E D +ES ++K SE
Sbjct: 989 HTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKV--SE 1046
Query: 397 GDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN 456
++T + ++ + KS D T + + ++ K SK+S+ + EE
Sbjct: 1047 NNETIK-DNILKTEKSSEEDLSGKHDTVTVSSDLDQFTKDDSKLSISPTALN---TEENV 1102
Query: 457 YKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKN 516
L+ +V E + + D N E T + SP +V+ + SP +
Sbjct: 1103 ACLQNIQHVEESVPNGVEDVLQTDDNMEICT--PDRSSPAKVE--------ETSPLGNAR 1152
Query: 517 LDARE-----KSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPA------SLTK 565
LD + K E P + +++ +S E K+ + V DS+ + S K
Sbjct: 1153 LDTPDINIVLKQDMATEHP-QAEVVKQESSMSESKV-LGEVGKQDSSSASLASAGESTGK 1210
Query: 566 DRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMT 625
+ + ++ + K+ + ++ P A +TS + +++ V +K Q + +
Sbjct: 1211 KEVAEKSQINLIDKKWKPLQGVGNLAAPNA--ATSSAVEVKVLTTVPEMKPQGLRIEIKS 1268
Query: 626 LNE-----RFTSYQKA--------TEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERV 672
N+ F +K +E S+ +++P R D S S +R E +
Sbjct: 1269 KNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPS---RDDDSQSRSPSRSRSKSETK- 1324
Query: 673 FKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYK 732
+ R S H R R S R S S G + +T Y+
Sbjct: 1325 ---------SRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYR 1375
Query: 733 SYKDDSKHKREQDHSRSSSSSASPSSPS------SREEKESKKEREEEFKTHHEMKEYS 785
SYK R SRS SSS P S S S + + R + ++H + Y+
Sbjct: 1376 SYKS----HRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYN 1430
Score = 77.4 bits (189), Expect = 5e-14
Identities = 188/857 (21%), Positives = 312/857 (36%), Gaps = 137/857 (15%)
Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRG 64
NS S S S SS S RS SR R RS SR+Y+RSRS +SR
Sbjct: 670 NSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRS---------- 719
Query: 65 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSR 124
R R R Y Y + + R+ RR RS S K+ SVS ++
Sbjct: 720 --RSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRS---SGKKNSVSHKKHS 774
Query: 125 SRSRRSY---------RSSRSPRSSSSRSSSPYSK-SPVSKRRGSQEKQTKKAEGEPQEE 174
S S ++ RSS + S SRSS YS S S + +Q Q K+ +G+ +
Sbjct: 775 SSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERT 834
Query: 175 SPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATP- 233
+ K++ E K E + S K + LS + + P + +
Sbjct: 835 HNKQEKNRGEEKSKSERECPHSKKRTLKEN---------LSDHLRNGSKPKRKNYAGSKW 885
Query: 234 PSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHI 293
S+S+S D KN+ + SH E + S S+ S IH
Sbjct: 886 DSESNSERDV--------TKNSKND-SHPSSDKEEGEATSD--------SESEVSEIHIK 928
Query: 294 --PSRRSPAKTIAPQ-NAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDR 350
P+ +S T P N S+ R+S G ++ + + S+ L
Sbjct: 929 VKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKRE 988
Query: 351 GNTRDKEASKEKGSEKGRAE--------------GEWEDQEALDYFSDKESGKQKFNDSE 396
+ KE K K +K +A GE E++E D +ES ++K SE
Sbjct: 989 HTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKV--SE 1046
Query: 397 GDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKN 456
++T + ++ + KS D T + + ++ K SK+S+ + EE
Sbjct: 1047 NNETIK-DNILKTEKSSEEDLSGKHDTVTVSSDLDQFTKDDSKLSISPTALNT---EENV 1102
Query: 457 YKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKN 516
L+ +V E + + D N E T + SP +V+ + SP +
Sbjct: 1103 ACLQNIQHVEESVPNGVEDVLQTDDNMEICT--PDRSSPAKVE--------ETSPLGNAR 1152
Query: 517 LDARE-----KSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPA------SLTK 565
LD + K E P + +++ +S E K+ + V DS+ + S K
Sbjct: 1153 LDTPDINIVLKQDMATEHP-QAEVVKQESSMSESKV-LGEVGKQDSSSASLASAGESTGK 1210
Query: 566 DRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMT 625
+ + ++ + K+ + ++ P A+ TS + +++ V +K Q + +
Sbjct: 1211 KEVAEKSQINLIDKKWKPLQGVGNLAAPNAA--TSSAVEVKVLTTVPEMKPQGLRIEIKS 1268
Query: 626 LNE-----------------RFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAG 668
N+ R Q+++ + T + + R SPS R +
Sbjct: 1269 KNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSR---SPSRSRSKSETKS 1325
Query: 669 EERVFKEENQKGDKKLRCDSADLRHDIDRRRKER-------SKERGDS----KGSRESSG 717
R + R ++ R R + R ++ R S K R SS
Sbjct: 1326 RHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSR 1385
Query: 718 SRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKE------SKKER 771
SR + + + +SY DS + R + SRS S + S S E
Sbjct: 1386 SRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSES 1445
Query: 772 EEEFKTHHEMKEYSGFA 788
+ + H E S ++
Sbjct: 1446 DRSYSHHRSPSESSRYS 1462
Score = 74.3 bits (181), Expect = 4e-13
Identities = 67/176 (38%), Positives = 85/176 (48%), Gaps = 18/176 (10%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNR 63
S+ ++ S S+S+S SRSRS+S + K R+R+RS +YS SRSR R + YR
Sbjct: 1298 SDEQTPSRDDDSQSRSPSRSRSKSET-KSRHRTRSVSYSHSRSRSRSSTSSYRS------ 1350
Query: 64 GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVS---- 119
R Y R R RG+Y G R YR + R S S R RS S P RS S
Sbjct: 1351 ---RSYS-RSRSRGWYSRGRTRSRSSSYRSYKSHRTS-SRSRSRSSSYDPHSRSRSYTYD 1405
Query: 120 SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEES 175
S SRSRSR RS RS RS + S+S S S+ ++ P E S
Sbjct: 1406 SYYSRSRSRS--RSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESS 1459
Score = 67.8 bits (164), Expect = 4e-11
Identities = 154/714 (21%), Positives = 265/714 (37%), Gaps = 93/714 (13%)
Query: 109 RSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 168
+ R S S S + S S SS S + + P KR + K+ +E
Sbjct: 187 KKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSE 246
Query: 169 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 228
EP+ + + K E DT E +S + K +I P +
Sbjct: 247 -EPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPP----VPENRFLLRRDM 301
Query: 229 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQ-------HSPERSGSGSVG--NGS 279
P+ T + AP++S K + S+ I+ H+P RS S S + S
Sbjct: 302 PVVTAEPEPKIPDVAPIVS---DQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDS 358
Query: 280 SRYSPSQNSPIHHIPSRRSPA--------KTIAPQNAPRDE----SRGRS-SFYPDGGDQ 326
S P + + + R P+ K P ++ DE R RS S+ D
Sbjct: 359 SETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDL 418
Query: 327 ETAK-TGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDK 385
TA+ +G KR +E +V +G + K + K ++K R + SD
Sbjct: 419 STARHSGHHKKR--RKEKKVKHKKKGK-KQKHCRRHKQTKKRR----------ILIPSDI 465
Query: 386 ESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTE-EEGLKYKSKVSLKG 444
ES K + E R R S L+ S S + + + L + S+ S +
Sbjct: 466 ESSKSSTRRMKSSCDRE----RSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRS 521
Query: 445 NRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLK 504
S + + T S ++ K + K+ R K+ ++SP + S+
Sbjct: 522 KSHSQSY--SRGSSRSRTASKSSSHSRSRSKSRSSSKSGHR---KRASKSPRKTASQ--- 573
Query: 505 DLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDS--HRPEVKLKMAPVPLDDSNRPAS 562
L +N + + PLR M +++ +P V + +PL DS P+
Sbjct: 574 --------LSENKPVKTE-------PLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSR 618
Query: 563 LTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSA 622
+ S ++ QE ++ H+ LP S + + + S +H +E+ +S
Sbjct: 619 WKPGQ---KPWKPSYERIQEMKAKTTHL-LPIQSTYSLANIKETGSSSSYHKREKNSESD 674
Query: 623 AMTLNERFTSYQKATEEHSTR-----QKSPEIHRRIDISPSTLRKHTRLAGEERVFKEEN 677
T ++ Y + E S R +S R S S H+R N
Sbjct: 675 QST----YSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRN 730
Query: 678 QKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKD--YKEYKSYK 735
+ D +C + I R+K R S G + S +K + + + +Y +
Sbjct: 731 KYSDHS-QCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGR 789
Query: 736 DDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEE---FKTHHEMKEYSG 786
D S R+ SRSS +S S SS + +S +E+E++ +TH++ ++ G
Sbjct: 790 DRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRG 843
Score = 64.7 bits (156), Expect = 4e-10
Identities = 58/143 (40%), Positives = 67/143 (46%), Gaps = 11/143 (7%)
Query: 3 RSNSRSHSSRSKSRSQSSS-RSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRN 61
RS S SHS RS+SRS +SS RSRS S SR + + SR RT SRS S R Y+ +
Sbjct: 1330 RSVSYSHS-RSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSS-----YRSYKSHRTS 1383
Query: 62 NRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQ 121
+R R Y R Y R R R RS R RS + + RS S
Sbjct: 1384 SRSRSRSSSYDPHSRSRSYTYDSYYSRSRSR----SRSQRSDSYHRGRSYNRRSRSCRSY 1439
Query: 122 RSRSRSRRSYRSSRSPRSSSSRS 144
S S S RSY RSP SS S
Sbjct: 1440 GSDSESDRSYSHHRSPSESSRYS 1462
Score = 57.4 bits (137), Expect = 6e-08
Identities = 132/582 (22%), Positives = 204/582 (35%), Gaps = 115/582 (19%)
Query: 2 GRSNSRSHSS-RSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYR 60
GR R H+ RS+S S+S S + K R R Y R S ++ D D
Sbjct: 335 GRGTIRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAY-RPPSGEKWSKGDKLSDPC 393
Query: 61 NNRGMRRPYGYRGRG---RGYYQGGGGRYHRG----------------GYRPVWNRRHSR 101
++R R R R GYY H G G + RRH +
Sbjct: 394 SSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQ 453
Query: 102 -----------------SPRRGRS---RSRSPKRRSVSSQRSRSR--------------- 126
S RR +S R RS + S+SS S R
Sbjct: 454 TKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTH 513
Query: 127 -SRRSYRS---SRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQ 182
SR SYRS S+S SSRS + S S+ R +K + +SP K+ SQ
Sbjct: 514 SSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQ 573
Query: 183 EEPKDTFEHDPSESIDEFNKSSATS---GDIWPGLSAYDNSPRSPHSPSPIATPPS---- 235
+ +P + N++ + P + D+ P S P PS
Sbjct: 574 LSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERI 633
Query: 236 ---QSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYS--PSQNSPI 290
++ + P+ ST +S N S S H E++ S S + S+YS S++SP
Sbjct: 634 QEMKAKTTHLLPIQST-YSLANIKETGSSSSYHKREKN-SESDQSTYSKYSDRSSESSPR 691
Query: 291 HHIPSRRSP------------AKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRF 338
S RS A + + +P S R+ + + +++ +
Sbjct: 692 SRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKY---SDHSQCSRSSSYTSIS 748
Query: 339 TDEESRVFLLDRGNTRDKEASKEKGSE-----------KGRAEGEW-----EDQEALDYF 382
+D+ R R + + S +K S KGR E + +LDY
Sbjct: 749 SDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYS 808
Query: 383 SDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSL 442
SD E + S + ++ + R K Q K+ ++ E + K +L
Sbjct: 809 SDSEQSSVQATQSAQEKEKQGQMERTHNK-----QEKN--RGEEKSKSERECPHSKKRTL 861
Query: 443 KGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSE 484
K N SD R K K Y + + + ++ KNS+
Sbjct: 862 KENL-SDHLR--NGSKPKRKNYAGSKWDSESNSERDVTKNSK 900
Score = 55.8 bits (133), Expect = 2e-07
Identities = 168/822 (20%), Positives = 289/822 (35%), Gaps = 138/822 (16%)
Query: 8 SHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRR 67
+HS S S S SSS S S S S + RSR R + R R S+ R++ ++ R
Sbjct: 193 THSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKR--SKKRRKEASSSEEPRN 250
Query: 68 PYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRS 127
+H+ +P+ RS + ++RSV S S R
Sbjct: 251 ------------------------------KHAMNPKGHSERSDTNEKRSVDS--SAKRE 278
Query: 128 RRSYRSSRSPRSSSSR----------SSSPYSKSP-----VSKRRGSQEKQTKKAEGEP- 171
+ R P +R ++ P K P VS ++ S K +K +G
Sbjct: 279 KPVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGT 338
Query: 172 -QEESPLKSKS--QEEPKDTFEHDP--SESIDEFNKSSATSGDIW--------PGLSAYD 218
+ +P +S+S + + D+ E P E + SG+ W P S +D
Sbjct: 339 IRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWD 398
Query: 219 NSPRSPHSPSPIATPPSQSSSCSDAPMLSTV-HSAKNTPSQHSHSIQHSPERSGSGSVGN 277
S S S S + SD LST HS + + ++H + G
Sbjct: 399 ERSLSQRSRSW-----SYNGYYSD---LSTARHSGHHKKRRKEKKVKHKKK----GKKQK 446
Query: 278 GSSRYSPSQNSPI---HHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKF 334
R+ ++ I I S +S + + SR S ++ +K+ K
Sbjct: 447 HCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKD 506
Query: 335 LKRFTDEESRVFL--------LDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKE 386
++ SR RG++R + ASK + R++ + + K
Sbjct: 507 VQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKS 566
Query: 387 SGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSL--KG 444
K SE + R ++ ++ N L S G
Sbjct: 567 PRKTASQLSENKPVKT----EPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPG 622
Query: 445 NRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLK 504
+ E +T +++ ST + +E +S +++ +Q K
Sbjct: 623 QKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYS 682
Query: 505 DLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLT 564
D S P ++ +R +S R S R + +AS R S+R S
Sbjct: 683 DRSSESSPRSRSRSSRSRSYSR--SYTRSRSLASSHSRSR----------SPSSRSHSRN 730
Query: 565 K----DRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFK 620
K + S+ S+ + R+ +L + K S S +H S + +Y K
Sbjct: 731 KYSDHSQCSRSSSYTSISSDDGRRA---KRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVK 787
Query: 621 SAAMTLNERFTSYQKATEEHSTRQKSPEIHRR-IDISPSTLRKHTRLAGEERVFKEENQK 679
+R + +K +E S+ S + + + + S K + E K+E +
Sbjct: 788 G-----RDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNR 842
Query: 680 GDKKLRCDSADLRHDIDRRRKERSKE--RGDSKGSRESSGSRKQEKTPKDYKEYKSYKDD 737
G++K + + + H R KE + R SK R K Y K D
Sbjct: 843 GEEKSKSER-ECPHSKKRTLKENLSDHLRNGSKPKR---------------KNYAGSKWD 886
Query: 738 SKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHH 779
S+ E+D +++S + + PS S +EE E+ + E E H
Sbjct: 887 SESNSERDVTKNSKNDSHPS--SDKEEGEATSDSESEVSEIH 926
Score = 55.1 bits (131), Expect = 3e-07
Identities = 163/794 (20%), Positives = 296/794 (37%), Gaps = 106/794 (13%)
Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHS----------RKKRYRSRSRTYSRSRSRDRMYSRD 54
+ R R R + RSRS S S K R R Y R S ++ D
Sbjct: 329 SGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAY-RPPSGEKWSKGD 387
Query: 55 YRRDYRNNRGMRRPYGYRGRG---RGYYQGGGGRYHRGGY------RPVWNRRHSRSPRR 105
D ++R R R R GYY H G + + V +++ + +
Sbjct: 388 KLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKH 447
Query: 106 GRSRSRSPKRR-----SVSSQRSRSRSRRS----YRSSRSPRSSSSRSSS-PYSKS--PV 153
R ++ KRR + S +S +R +S RSSRS SS SS +SKS V
Sbjct: 448 CRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDV 507
Query: 154 SKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPG 213
+ + +++ Q S S+S+ K + H S S ++SS+ SG
Sbjct: 508 QSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSS-SHSRSRS---KSRSSSKSG----- 558
Query: 214 LSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQH--SHSIQHSPERSG 271
+ R+ SP A+ S++ P+ +T+ +N Q + +I P
Sbjct: 559 -----HRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPL--- 610
Query: 272 SGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKT 331
S SR+ P Q P + S + I A S Y +ET +
Sbjct: 611 --SDSPPPSRWKPGQK------PWKPS-YERIQEMKAKTTHLLPIQSTYSLANIKETGSS 661
Query: 332 GKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQK 391
+ KR + ES + + R E+S S R+ S S +
Sbjct: 662 SSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSR------------SYSRSYTRS 709
Query: 392 FNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRN-TEEEGLKYKSKVSLKGNRESDG 450
+ + + R ++ +D + ++S+ + + ++G + K ++ G + S
Sbjct: 710 RSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVS 769
Query: 451 FRE--EKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFD 508
++ + K + YV R ++ + E ++S + E S + +S + K +
Sbjct: 770 HKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEK---E 826
Query: 509 YSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRL 568
+ + + +EK+ E+S S+ P K + L D R S K +
Sbjct: 827 KQGQMERTHNKQEKNRGEEKS-------KSERECPHSKKRTLKENLSDHLRNGSKPKRKN 879
Query: 569 LASTLVHS-VKKEQEFRSIFDHIKLPQASKSTSE--SFIQHIVSLVHHVKEQYFKSAAMT 625
A + S E++ + P + K E S + VS +H + KS+ T
Sbjct: 880 YAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNT 939
Query: 626 LNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLR 685
K++++ ++ S + + +KH + +E + +E +K +KL+
Sbjct: 940 SLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKH-KHGSKENLKREHTKKVKEKLK 998
Query: 686 CDSADLRHDIDRRR------------KERSKERGDSKGSRESSGSRKQE--KTPKD--YK 729
D +H +R+ +E +E D + ++ES + E +T KD K
Sbjct: 999 -GKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILK 1057
Query: 730 EYKSYKDDSKHKRE 743
KS ++D K +
Sbjct: 1058 TEKSSEEDLSGKHD 1071
Score = 43.1 bits (100), Expect = 0.001
Identities = 41/140 (29%), Positives = 53/140 (37%), Gaps = 12/140 (8%)
Query: 704 KERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSS-SASPSSPSSR 762
KE G S SS ++++ + D Y Y D S + SRSS S S S S SR
Sbjct: 656 KETGSS-----SSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSR 710
Query: 763 EEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGR 822
S H +YS + SR DDG +R + R +
Sbjct: 711 SLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDG-----RRAKRRLRSSGKK 765
Query: 823 GRFNFKK-SGSSPKWTHDKY 841
+ KK S SS K H KY
Sbjct: 766 NSVSHKKHSSSSEKTLHSKY 785
Score = 40.0 bits (92), Expect = 0.009
Identities = 92/436 (21%), Positives = 160/436 (36%), Gaps = 80/436 (18%)
Query: 386 ESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKV--SLK 443
E ++K SEG D+ S + + S + H + K + KV S K
Sbjct: 186 EKKRKKPTHSEGSDSSSN--------SSSSSESSSESELEHERSRRRKHKRRPKVKRSKK 237
Query: 444 GNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKL 503
+E+ E +N ER T + + + E+ V+ PE++
Sbjct: 238 RRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVR-----PEEI----- 287
Query: 504 KDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLK-MAPVPLDDSNRPAS 562
PP+ +N + R + P+ + PE K+ +AP+ S++ S
Sbjct: 288 -------PPVPEN-----RFLLRRDMPVV-------TAEPEPKIPDVAPIV---SDQKPS 325
Query: 563 LTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKE--QYFK 620
++K S +K + +I H P S+S SES H KE Q +
Sbjct: 326 VSK----------SGRKIKGRGTIRYHT--PPRSRSCSESDDDDSSETPPHWKEEMQRLR 373
Query: 621 SAAMTLNERFTSYQKATEEHSTRQKSPEIHRRI----------DISPSTLRKHTRLAGEE 670
+ E+++ K ++ S+R + +R D+S + H + +E
Sbjct: 374 AYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKE 433
Query: 671 RVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGS--RKQEKTPKDY 728
+ K + +KG K+ C RR K+ K R ESS S R+ + +
Sbjct: 434 KKVKHK-KKGKKQKHC----------RRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRE 482
Query: 729 KEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFA 788
+ +S S H ++D S+S S + SSR+ SK + + + S +
Sbjct: 483 RSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSS 542
Query: 789 GVSRPRGTFHDDRDDG 804
SR R G
Sbjct: 543 SHSRSRSKSRSSSKSG 558
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 79.3 bits (194), Expect = 1e-14
Identities = 160/754 (21%), Positives = 271/754 (35%), Gaps = 58/754 (7%)
Query: 2 GRSNSRSHSSRSKSRS-----QSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYR 56
GR R R K RS Q S SR HS + S + +S S R R S Y+
Sbjct: 301 GRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQ 360
Query: 57 RDYRNN-RGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSR-SPRRGRSRSRSPK 114
R R PY + R HR R H R S R R
Sbjct: 361 RTLTPPLRRSASPYPSHSLSSPQRKQSPPR-HRSPMREKGRHDHERTSQSHDRRHERRED 419
Query: 115 RRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEE 174
R + SR R Y +S P R +++++ + + ++
Sbjct: 420 TRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDS 479
Query: 175 SPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPP 234
++ S++ + D + D + D Y RS + + +
Sbjct: 480 REMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRS-YGRNHLREES 538
Query: 235 SQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIP 294
S++ +++ S + + + PE+ GS GS S S NS H
Sbjct: 539 SRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGS--RGSQIDSHSSNSNYHDSW 596
Query: 295 SRRS--PAKTIAPQNAPRDESRGRSSFYPDGGDQETAKT--------------GKFLKRF 338
RS P + P+ RD++R SSF G+++ G+ +
Sbjct: 597 ETRSSYPERDRYPERDNRDQARD-SSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELE 655
Query: 339 TDEESRVFLLDRGNTRDKEASKEKGSEKGR-AEGEWEDQEALDYFSDKESGKQKFNDSEG 397
DE +DR + R E ++E+ E+ R E E E + D +KE ++ E
Sbjct: 656 RDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARER 715
Query: 398 DDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNY 457
+ E E R+ + D+ + R E E + + + + RE + RE +
Sbjct: 716 EREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERE 775
Query: 458 KLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSE---KLKDLFDYSPPLH 514
+ +E ER +DK K D E+ +E ++P E K + + SP
Sbjct: 776 RARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPR 835
Query: 515 KNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSN--RPASLTKDRLLAST 572
++ R RE SP + D + +L V +S P+ LT+DR
Sbjct: 836 QSPKRR-----REHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDR----- 885
Query: 573 LVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQ--YFKSAAMTLNERF 630
KE++ + + ++S+ E ++ VS V +EQ +S+ M +
Sbjct: 886 --QGRWKEEDRKP-----ERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDII 938
Query: 631 TSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTR-LAGEERVFKEENQKGDKKLRCDSA 689
+Q E S R E ++ I ++K G ER E + +
Sbjct: 939 GHHQSEDRETSDRAHD-ENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKG 997
Query: 690 DLRHDIDRRRKERSKERGDSKGSRESSGSRKQEK 723
+ I+++RK K +GDS S E + + ++K
Sbjct: 998 QKKKSIEKKRK---KSKGDSDISDEEAAQQSKKK 1028
Score = 69.3 bits (168), Expect = 1e-11
Identities = 157/744 (21%), Positives = 267/744 (35%), Gaps = 91/744 (12%)
Query: 107 RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKK 166
R S+SPKR+S S S+ R + SP R+ SK+ SK++G +T
Sbjct: 213 RKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRN----SKTNQSKKKG---PRTPS 265
Query: 167 AEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSP-- 224
E+ L K +E+ K + I+E + G + + PRS
Sbjct: 266 PPPPIPEDIALGKKYKEKYK------VKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSP 319
Query: 225 ----HSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPS-QHSHSIQHSPERSGSGSVGNGS 279
HSP S S S S S K TPS + ++ RS S +
Sbjct: 320 AGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSL 379
Query: 280 SRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFT 339
S Q+ P H P R R + S + ++ GK +
Sbjct: 380 SSPQRKQSPPRHRSPMREK----------GRHDHERTSQSHDRRHERREDTRGKRDREKD 429
Query: 340 DEESRVFLLDRGNTRDKEASKEKGSEKGRAEG-EWEDQEALDYFSDKESGKQKFNDSEGD 398
E R + D+ ++RD +E + R + + D+ L D ++ + S
Sbjct: 430 SREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSR-- 487
Query: 399 DTEETEDYRQFRKSVLA-DQGKSFATASHRNTE---EEGLKY--------KSKVSLKGNR 446
DT+E+ D R R + A D +HR + EE Y S+ ++
Sbjct: 488 DTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNES 547
Query: 447 ESDGFREEKNYKL-KETGYVVERP--------STTKDKHKE----EDKNSERITVKKETQ 493
++ E +N ++ + G V E P + D H D R + + +
Sbjct: 548 RNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDR 607
Query: 494 SPEQVKSEKLKD-LFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPV 552
PE+ ++ +D F+ D RE+ R SP+R + + R E + +
Sbjct: 608 YPERDNRDQARDSSFERRHGERDRRDNRERDQ-RPSSPIRHQGRNDELERDERREERRVD 666
Query: 553 PLDD------SNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQH 606
+DD R +DR +E+E + + + + + +
Sbjct: 667 RVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRE 726
Query: 607 IVSLVHHVKEQYFKSAAMTLNERFTSYQKATE-EHSTRQKSPEIHRRIDISPSTLRKHTR 665
H +E+ ER +K E E R++ E R + R+ R
Sbjct: 727 RDRDRDHDRERE--------RERERDREKEREREREERERERERERERERERERERERAR 778
Query: 666 LAGEERVFK---EENQKGDKKLRCDSADLRHDIDRR-----RKERSKERGDSKGSRESSG 717
+ER + E+ KG R ++R D + R RK + + R + S S
Sbjct: 779 ERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSP 838
Query: 718 SRKQEKTPKDYKEYKSYKD-DSKHK------REQDHSRSSSSSASPSSPSSREEKESKKE 770
R++E +P D Y S D + KH+ R Q+ S S + +E++ K E
Sbjct: 839 KRRREHSP-DSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPE 897
Query: 771 REEEFKTHHEMKEYSGFAGVSRPR 794
R+E + + E + + V + R
Sbjct: 898 RKESSRRYEEQELKEKVSSVDKQR 921
Score = 57.0 bits (136), Expect = 7e-08
Identities = 164/842 (19%), Positives = 298/842 (35%), Gaps = 133/842 (15%)
Query: 99 HSRSPR-RGRSRS--RSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSK 155
H SPR +G S + RSP+R + R R +++R + + ++ SSSP K
Sbjct: 61 HGPSPRGKGYSSNYRRSPERPT-GDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRG 119
Query: 156 RRGSQE--KQTKKAEGEPQEES-----------------------PLKSKSQEEPKDTF- 189
R +E K TK+ E +EE+ L+ K Q+ ++
Sbjct: 120 RHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMK 179
Query: 190 -EHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLST 248
E + E +E S ++ RS SPSP S+S +P S+
Sbjct: 180 LEQENMEKREEIIIKKEVSPEV----------VRSKLSPSPSLRKSSKSPKRKSSPKSSS 229
Query: 249 VHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNA 308
S S + S + N S + P SP IP + K +
Sbjct: 230 ASKKDRKTSAVSSPLLDQQRNSKT----NQSKKKGPRTPSPPPPIPEDIALGKKYKEKYK 285
Query: 309 PRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGR 368
+D +E + GK DRG RD E +EK +
Sbjct: 286 VKDRI------------EEKTRDGK---------------DRG--RDFERQREKRDKPRS 316
Query: 369 AEGEWEDQEALD---YFSDKESGK--QKFNDSEGDDTEETEDYRQ-----FRKSV----- 413
+ + + S +SG Q+ + S + Y++ R+S
Sbjct: 317 TSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPS 376
Query: 414 --LADQGKSFATASHRNT-EEEGLKYKSKVSLKGNRESD------GFREEKNYKLKETGY 464
L+ + + HR+ E+G + S +R + G R+ + +E Y
Sbjct: 377 HSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREY 436
Query: 465 VVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEK----LKDLFDYSPPLHKNLDAR 520
++ S+ + E ++ ++T+ +++ + +++ DYS ++ D R
Sbjct: 437 EQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPR 496
Query: 521 EKSTFREESPLRIKMIASDSHR-----PEVKLKMAPVPLDDSNRPASLTKDRLLASTLVH 575
+ + R+ R + D+HR PE L + + + + S
Sbjct: 497 DSRSTRDAHDYRDRE-GRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESR--S 553
Query: 576 SVKKEQEFRSIFDHIKLPQASK--STSESFIQHIVSLVHH----VKEQYFKSAAMTLNER 629
++ ++ RS +LP+ S H + +H + Y + +
Sbjct: 554 EIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDN 613
Query: 630 FTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGE-ERVFKEENQKGDK-----K 683
+ ++ E ++ +R D PS+ +H E ER + E ++ D+
Sbjct: 614 RDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRD 673
Query: 684 LRCDSADLRHDIDRRR-KERSKERG-DSKGSRESSGSRKQEKTPKDYKEYKSYKD-DSKH 740
R D + DR R +ER +ER + + RE R +E+ + KE +D D H
Sbjct: 674 ERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDH 733
Query: 741 KREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDD 800
RE++ R E+E ++ERE E + E +E + R R +D
Sbjct: 734 DRERERERERDREKEREREREERERERERERERERERERE-RERARERDKERERQRDWED 792
Query: 801 RDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEK 860
+D G D R R + R + G + + +Y+ +G + E
Sbjct: 793 KDKGRD---DRREKREEIREDRN----PRDGHDERKSKKRYRNEGSPSPRQSPKRRREHS 845
Query: 861 KD 862
D
Sbjct: 846 PD 847
Score = 54.7 bits (130), Expect = 4e-07
Identities = 158/826 (19%), Positives = 276/826 (33%), Gaps = 152/826 (18%)
Query: 7 RSHSSRSKSRSQSSSRSRSRSHSRKK-RYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGM 65
R +R + R + R R R R++ R R + R R R+R+R R+ RD +R
Sbjct: 672 RDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRD- 730
Query: 66 RRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRS 125
R H +R R R R + R +R +R R
Sbjct: 731 -------------------RDH--------DRERERERERDREKEREREREERERERERE 763
Query: 126 RSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEP 185
R R R R+ + K +G +++ K+ E + P
Sbjct: 764 RERERERERERERARERDKERERQRDWEDKDKGRDDRREKREE----------IREDRNP 813
Query: 186 KDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPM 245
+D HD +S + R+ SPSP +P + D+
Sbjct: 814 RDG--HDERKSKKRY---------------------RNEGSPSPRQSPKRRREHSPDSDA 850
Query: 246 LSTVHSAKNTPSQHSHSIQHSPERSGSGS--VGNGSSRYSPSQNSPIHHIPSRRSPAKTI 303
++ S ++ RS S S + R+ P SRR + +
Sbjct: 851 YNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQEL 910
Query: 304 APQNAPRDESRGRSSFYPDGGDQETAKTGKFLK--RFTDEESRVFLLDRGNTRDKEASKE 361
+ + D+ R ++ + G R T + + + + K K+
Sbjct: 911 KEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKK 970
Query: 362 KGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRK--SVLADQGK 419
K + G G E + E G Q F+ +G + E R+ K S ++D+
Sbjct: 971 KEDDVGIERGNIE--------TTSEDG-QVFSPKKGQKKKSIEKKRKKSKGDSDISDEEA 1021
Query: 420 SFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHK-E 478
+ + R + K ++ N ++ G E+ K ++T + D+ +
Sbjct: 1022 AQQSKKKRGPRTPPITTKEELVEMCNGKN-GILEDSQKK-EDTAFSDWSDEDVPDRTEVT 1079
Query: 479 EDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFR----------EE 528
E +++ T T SP L L PP+ +T
Sbjct: 1080 EAEHTATATTPGSTPSP-------LSSLLPPPPPVATATATTVPATLAATTAAAATSFST 1132
Query: 529 SPLRIKMIAS------------DSHR------------PEVKLKMAP--VPLDD------ 556
S + I A+ DSHR P V ++ A P+D
Sbjct: 1133 SAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSL 1192
Query: 557 ----SNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVH 612
SNR + + R ++ H +Q R H K+ S S +
Sbjct: 1193 GSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRID 1252
Query: 613 HVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERV 672
+K + + T ++R S HS+R+ SPE R++ + RL +R
Sbjct: 1253 QLKRG--EPSRSTSSDRQDS-----RSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRY 1305
Query: 673 ---FKEENQKGDKKLRCDSADLRHDIDRRR-KERSKERGDSKGSRESSGSRKQEKTPKDY 728
+ E ++ D + R D D R R ++R +ER RE ++++ D
Sbjct: 1306 EHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRER-----ERERERDKRRD---LDR 1357
Query: 729 KEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEE 774
+ + D + R++D R+ SS S + E + ER+ E
Sbjct: 1358 ERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLE 1403
Score = 48.1 bits (113), Expect = 3e-05
Identities = 129/656 (19%), Positives = 233/656 (35%), Gaps = 129/656 (19%)
Query: 307 NAPRDESRGRSSFY------PDGGDQETAKTGKF------LKRFTDEESRVFLLD--RGN 352
+ P +G SS Y P G +E K + KR T+E S + RG
Sbjct: 61 HGPSPRGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGR 120
Query: 353 TRDKE---ASKEKGSEKGRAEGEWE------DQEALDY-FSDKESGKQKFNDSEGDDTEE 402
R+KE +KE+ E EWE D ++Y + + S + K + + +
Sbjct: 121 HREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKL 180
Query: 403 TEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKET 462
++ + R+ ++ + S + + L+ SK + + +K+ K
Sbjct: 181 EQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAV 240
Query: 463 GYVV---ERPSTTKDKHKEEDKNS-------ERITVKKETQSPEQVKS---EKLKDLFDY 509
+ +R S T K+ + E I + K+ + +VK EK +D D
Sbjct: 241 SSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDR 300
Query: 510 SPPLHKNLDAREKSTF-----REESPLRIKMIASDS--------HRPEVKLKMAPVPLDD 556
+ + R+K + SP+ + +S S H P + K P P
Sbjct: 301 GRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSP--S 358
Query: 557 SNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKE 616
R + R + HS+ Q +S H + P K H E
Sbjct: 359 YQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRH-RSPMREKG-------------RHDHE 404
Query: 617 QYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEE 676
+ +S ++R ++ T R+K R + S+ R H +++
Sbjct: 405 RTSQS-----HDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDH----------RDD 449
Query: 677 NQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYK------E 730
+ D + R D+ D R DRR S++ DS+ R+ S K+ + P+D + +
Sbjct: 450 REPRDGRDRRDARDTR---DRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHD 506
Query: 731 YKSYKDDSKHKRE-----------QDHSRSSSSSASPSSPSSRE---------------- 763
Y+ + H++E ++H R SS + S E
Sbjct: 507 YRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGR 566
Query: 764 -----EKESKKEREEEFKTHHEMKEY-----SGFAGVSRPRGTFHDDRDDGVDYWAKRGR 813
EK S+ R + +H Y + + R R D+RD D +R
Sbjct: 567 VPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRH 626
Query: 814 GRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVEDEEETMENNEEKKDRRKEEKE 869
G + R R S + +D+ + D EE ++ ++++D R E++
Sbjct: 627 GERDRRDNRERDQRPSSPIRHQGRNDELERD--ERREERRVDRVDDRRDERARERD 680
Score = 43.5 bits (101), Expect = 8e-04
Identities = 59/204 (28%), Positives = 77/204 (37%), Gaps = 39/204 (19%)
Query: 15 SRSQSSSRSRSRSHS-RKKRYRSRSRTYSRSRS---RDRMYSRDYRRDYRNNRGMRRPYG 70
SRS SS R SRSHS R+ S + +SRS S RDR+ RD R RR
Sbjct: 1260 SRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTR 1319
Query: 71 YRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRS-PKRRSVSSQRSRSRSRR 129
R R + W R R R R R R KRR + +R R S
Sbjct: 1320 QREWDRDADKD-------------WPRNRDRDRLRERERERERDKRRDLDRERERLISDS 1366
Query: 130 SYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG--EPQEESPLKSKSQEE--- 184
R R + S SQ + K+ E E + E L+S S++
Sbjct: 1367 VERDRDRDRDRTFES--------------SQIESVKRCEAKLEGEHERDLESTSRDSLAL 1412
Query: 185 PKDTFEHD--PSESIDEFNKSSAT 206
K+ + D + +E NKS T
Sbjct: 1413 DKERMDKDLGSVQGFEETNKSERT 1436
Score = 30.4 bits (67), Expect = 7.4
Identities = 26/139 (18%), Positives = 53/139 (38%), Gaps = 6/139 (4%)
Query: 736 DDSKHKREQDHSRSSS-----SSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGV 790
+D++H++ D RSSS S+ S +S R R + ++ + +SG
Sbjct: 1176 EDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDR 1235
Query: 791 SRPRG-TFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGDGIVED 849
+ + +R +D + R T + + SSP+ + G +
Sbjct: 1236 EKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDS 1295
Query: 850 EEETMENNEEKKDRRKEEK 868
+ E + + DR +E +
Sbjct: 1296 RDRLQERDRYEHDRERERE 1314
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 78.6 bits (192), Expect = 2e-14
Identities = 127/660 (19%), Positives = 213/660 (32%), Gaps = 15/660 (2%)
Query: 110 SRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEG 169
S S S SS S S S SS S S SS SS S S S + K++
Sbjct: 567 SDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDS 626
Query: 170 EPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSP 229
E S S+ + D+ D S++ D + S++++ + D+S S S S
Sbjct: 627 SKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS-----DSSDSSDSSDSSSSS 681
Query: 230 IATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSP 289
++ S SS SD+ S + ++ S S + S S + SS S S NS
Sbjct: 682 DSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS- 740
Query: 290 IHHIPSRRSPAKTIAPQNAPRDES-RGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLL 348
S S + + + D S SS D D + D +
Sbjct: 741 -----SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSS 795
Query: 349 DRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQ 408
D N+ D S + ++ + + SD + S+ D+ + D
Sbjct: 796 DSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDS 855
Query: 409 FRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVER 468
+S ++ S ++ N+ + S S + SD + +
Sbjct: 856 SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSS 915
Query: 469 PSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPL-HKNLDAREKSTFRE 527
S+ E +S+ + S + S + D S N S +
Sbjct: 916 DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD 975
Query: 528 ESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIF 587
S +SDS + + +S + D +S +S S
Sbjct: 976 SSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS-S 1034
Query: 588 DHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSP 647
D +S S+ S + ++ + + +S + + S S
Sbjct: 1035 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSS 1094
Query: 648 EIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERG 707
+ D S S+ + + + + D DS+D + D S +
Sbjct: 1095 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154
Query: 708 DSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES 767
DS S +SS S D + + D S D S SS SS S S S + +S
Sbjct: 1155 DSSDSSDSSDS-SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1213
Score = 78.2 bits (191), Expect = 3e-14
Identities = 144/710 (20%), Positives = 241/710 (33%), Gaps = 33/710 (4%)
Query: 100 SRSPRRGRSRSRSPKRRSVS-SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRG 158
S + S+S S S S S S S S S +S S SS+S +SS S S S
Sbjct: 619 SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSS 678
Query: 159 SQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSA-----TSGDIWPG 213
S + ++ +S S+S + D+ + D S+S D N +S+ S D
Sbjct: 679 SSSDSSNSSDSSDSSDSSNSSESSDS-SDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS 737
Query: 214 LSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSG 273
++ D+S S S S ++ S SS+ SD+ S+ ++ S S + S + S S
Sbjct: 738 SNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS-----DSSDSSDSSDSSNSSDSNDSSNS- 791
Query: 274 SVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGK 333
S + SS S S NS S S + + ++ SS D D + G
Sbjct: 792 SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS 851
Query: 334 FLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFN 393
+D +R D N+ D S + + ++ ++ S+ N
Sbjct: 852 ----DSDSSNR---SDSSNSSDSSDSSDSSNSSDSSDSSDSNES-----SNSSDSSDSSN 899
Query: 394 DSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFRE 453
S+ D ++ + S +D +S ++ + N+ + S S + SD
Sbjct: 900 SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNS 959
Query: 454 EKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPL 513
+ ++ S+ + +S+ + S S D D S
Sbjct: 960 SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS--- 1016
Query: 514 HKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTL 573
+ D+ S S +SDS + + +S + D +S
Sbjct: 1017 -NSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1075
Query: 574 VHSVKKEQEFRSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSY 633
S E D +S S+ S +++ + + +S
Sbjct: 1076 SDS-SDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1134
Query: 634 QKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRH 693
+ S S E D S S+ + + + + + D DS+D
Sbjct: 1135 SSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1194
Query: 694 DIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSS 753
D S + DS S +SS S D + D S D S SS S
Sbjct: 1195 SSDSSDSSDSSDSSDSSDSSDSSDS-SDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDS- 1252
Query: 754 ASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDD 803
S SS SS +S E + + K+ + S S + H DD
Sbjct: 1253 -SDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 73.9 bits (180), Expect = 6e-13
Identities = 151/766 (19%), Positives = 240/766 (31%), Gaps = 66/766 (8%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNR 63
SNS S S S S S SS S S S S + S S D S D + D
Sbjct: 574 SNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSD---SSDSKSD----- 625
Query: 64 GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRS 123
+ + + +S S S + S S S S
Sbjct: 626 --------SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDS 677
Query: 124 RSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQE 183
S S S S S S SS SS S S S + + + S S +
Sbjct: 678 SSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSD----SSNSSD 733
Query: 184 EPKDTFEHDPSESIDEFNKS-SATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSD 242
+ D S+S D N S S+ S D + D+S S S S ++ + SS+ SD
Sbjct: 734 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSD 793
Query: 243 APMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKT 302
+ S + N+ S S S S S + S + SS S S NS S S
Sbjct: 794 SSDSSNSSDSSNS-SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSD 852
Query: 303 IAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEK 362
N R +S SS D D + + + D N+ D ++S
Sbjct: 853 SDSSN--RSDS-SNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSS 909
Query: 363 GSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFA 422
S D SD + N S+ D+ ++ + S + +
Sbjct: 910 NSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 969
Query: 423 TASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKN 482
++ ++ + S S + SD + ++ + +++ + + N
Sbjct: 970 DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029
Query: 483 SERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHR 542
S + S + S D D S + + D+ + S + S +SDS
Sbjct: 1030 S-----SDSSDSSDSSDSSDSSDSSDSSDSSNSS-DSSDSSDSSDSSDSSDSSDSSDSSE 1083
Query: 543 PEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSES 602
D S+ S S+ + D +S S+ S
Sbjct: 1084 SS----------DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1133
Query: 603 FIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRK 662
++ + N +S + + S S + D S S+
Sbjct: 1134 ------------------DSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSS 1175
Query: 663 HTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQE 722
+ + + + + D DS+D D S + DS S +SS S +
Sbjct: 1176 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNES- 1234
Query: 723 KTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESK 768
+ D S D S SS SS S S + + +SK
Sbjct: 1235 ------SDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274
Score = 63.2 bits (152), Expect = 1e-09
Identities = 125/651 (19%), Positives = 217/651 (33%), Gaps = 33/651 (5%)
Query: 133 SSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHD 192
+S S +SSSR + Y+ S SK G+ +K AE + + + + S +D
Sbjct: 478 NSESDNNSSSRGDASYN-SDESKDNGNGS-DSKGAEDDDSDSTSDTNNSDSNGNGNNGND 535
Query: 193 PSESIDEFN-KSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHS 251
++ D KS ++ D ++ D+S S S S SSS SD+ + S
Sbjct: 536 DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSS-----DSNSSSDSDSSDSDSSDS 590
Query: 252 AKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRD 311
+ + S S+S S S S + S S S +S S + ++ D
Sbjct: 591 SDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSS------KSESDSSDSDSKSDSSD 644
Query: 312 ESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRD----KEASKEKGSEKG 367
+ SS D D + +D D N+ D ++S S
Sbjct: 645 SNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDS 704
Query: 368 RAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATASHR 427
+ + ++ D + S N S+ D+ + D S ++ S ++
Sbjct: 705 SDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS--SNSSDSSDSSDSS 762
Query: 428 NTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERIT 487
N+ + S S + SD + ++ + +++ + +S+
Sbjct: 763 NSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSN 822
Query: 488 VKKETQSPEQVKSEKLKDLFDYS-------PPLHKNLDAREKSTFREESPLRIKMIASDS 540
+ S + S D D S D+ S + S +SDS
Sbjct: 823 SSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS 882
Query: 541 HRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKK--EQEFRSIFDHIKLPQASKS 598
+ D SN S + D +S S E + D+ +S S
Sbjct: 883 SDSNESSNSSD-SSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNS 941
Query: 599 --TSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDIS 656
+S+S S + + S + N +S + + S S + D S
Sbjct: 942 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1001
Query: 657 PSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESS 716
S+ + + + + + D DS+D D S + DS S +SS
Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061
Query: 717 GSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKES 767
S D + D S+ D S SS SS S S S + +S
Sbjct: 1062 DS-SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDS 1111
Score = 62.8 bits (151), Expect = 1e-09
Identities = 106/527 (20%), Positives = 168/527 (31%), Gaps = 16/527 (3%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYR-RDYRNN 62
S+ S SS S S SS+ S S S S + S S D S D D N+
Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823
Query: 63 RGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQR 122
G NR S + S S S
Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS 883
Query: 123 SRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQ 182
+ S S SS S SS S SS + S S S + +E ++ S S
Sbjct: 884 DSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDS----SESSNSSDNSNSSDSS 939
Query: 183 EEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSD 242
+ D S S D N S +++ ++ D+S S S S ++ S SS SD
Sbjct: 940 NSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSD 999
Query: 243 APMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKT 302
+ S + ++ + S + S + S + SS S S +S S S +
Sbjct: 1000 SSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1059
Query: 303 IAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEK 362
+ + D S SS D D + +D D ++ D S +
Sbjct: 1060 SSDSSDSSDSS--DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117
Query: 363 GSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFA 422
++ D SD + + SE D+ ++ D S +D S
Sbjct: 1118 SDSSNSSDS--SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDS--SDSSDSSD 1173
Query: 423 TASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKN 482
++ N+ + S S + SD + ++ + S + D D N
Sbjct: 1174 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD-SSDSSDSSDSSDSN 1232
Query: 483 SERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREES 529
+ S + S D D S D+ ++S + +S
Sbjct: 1233 ES----SDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKS 1275
Score = 60.8 bits (146), Expect = 5e-09
Identities = 125/664 (18%), Positives = 212/664 (31%), Gaps = 51/664 (7%)
Query: 109 RSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAE 168
+S S K +S SS S S S SS S S SS S+S S S + + +
Sbjct: 539 KSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNS-------SSDSDSSDSDSSDSS 591
Query: 169 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 228
+S S S + + D S+S D + SS + D S S S
Sbjct: 592 DSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD-------------SSDSDS 638
Query: 229 PIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNS 288
+ S SS SD S + N+ + S S S S + SS S S +S
Sbjct: 639 KSDSSDSNSSDSSDN---SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDS 695
Query: 289 PIHHIPSRRSPA----KTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESR 344
S S + + + ++ + S SS D D + ++
Sbjct: 696 SNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDS 755
Query: 345 VFLLDRGNTRD-KEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEET 403
D N+ D ++S S + D SD + N S+ D+ ++
Sbjct: 756 SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDS 815
Query: 404 EDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETG 463
D S ++ S +++ ++ + S NR + + ++
Sbjct: 816 SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS----DSS 871
Query: 464 YVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKS 523
++ E NS + + + S D D S + D+ E S
Sbjct: 872 DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS----NSSDSSESS 927
Query: 524 TFREESPLRIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEF 583
+ S +SDS DS+ ++ + + + S +
Sbjct: 928 NSSDNSNSSDSSNSSDS--------------SDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973
Query: 584 RSIFDHIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTR 643
D +S S+ S + ++ + N +S + S
Sbjct: 974 SDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS 1033
Query: 644 QKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERS 703
S + D S S+ + + + + + D DS+D D S
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNS 1093
Query: 704 KERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSRE 763
+ DS S +SS S D + + D S D S SS+SS S S S +
Sbjct: 1094 SDSSDSSDSSDSSDS-SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSD 1152
Query: 764 EKES 767
+S
Sbjct: 1153 SSDS 1156
Score = 53.5 bits (127), Expect = 8e-07
Identities = 87/395 (22%), Positives = 119/395 (30%), Gaps = 25/395 (6%)
Query: 5 NSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRG 64
NS S S + S S SS S + S S S S S S S D S + ++
Sbjct: 932 NSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS 991
Query: 65 MRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSR 124
N S + S S S
Sbjct: 992 SDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1051
Query: 125 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEE 184
S S S SS S SS S SS S S S + ++ +S S S +
Sbjct: 1052 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDS 1111
Query: 185 PKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAP 244
+ D S S D + S+ S D ++ D+S S S S ++ S SS SD+
Sbjct: 1112 SDSSDSSDSSNSSD--SSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169
Query: 245 MLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIA 304
S + N+ S S S + SS S S +S S S + +
Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229
Query: 305 PQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGS 364
N D S D D + +D +T D + S
Sbjct: 1230 DSNESSDSS--------DSSDSSDSSNSSDSSDSSDSSD--------STSDSNDESDSQS 1273
Query: 365 EKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDD 399
+ G D SD +S N S DD
Sbjct: 1274 KSGNGNNNGSD-------SDSDSEGSDSNHSTSDD 1301
Score = 30.4 bits (67), Expect = 7.4
Identities = 29/130 (22%), Positives = 43/130 (33%), Gaps = 29/130 (22%)
Query: 673 FKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGD----------------SKGSRE-- 714
F +++ +GD D ++ D + S RGD SKG+ +
Sbjct: 455 FDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDD 514
Query: 715 -----------SSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSRE 763
S+G+ D + K DS D S SS SS S S SS
Sbjct: 515 SDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDS 574
Query: 764 EKESKKEREE 773
S + +
Sbjct: 575 NSSSDSDSSD 584
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 78.6 bits (192), Expect = 2e-14
Identities = 78/217 (35%), Positives = 104/217 (47%), Gaps = 22/217 (10%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRS-RSRTYSRSRSRDRMYSRDYRRDYR- 60
RS SRS R SRS+S SR R RS S++KR RS + R+ SR R R R SRD R+ R
Sbjct: 1862 RSRSRSRRRRRSSRSRSKSRGR-RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRA 1920
Query: 61 -----NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-RRGRS---RSR 111
+ R R R R GR P R SR+P RR R+ RSR
Sbjct: 1921 RSRTPSRRSRSHTPSRRRRSRSV-----GRRRSFSISP---SRRSRTPSRRSRTPSRRSR 1972
Query: 112 SPKRRS-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGE 170
+P RRS S+RSR+ SRRS SR RS S +S SPV RR + + +
Sbjct: 1973 TPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSP 2032
Query: 171 PQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATS 207
+ + S+ PK + D ++ + E K++A +
Sbjct: 2033 IRRKRSRSSERGRSPKRLTDLDKAQLL-EIAKANAAA 2068
Score = 71.6 bits (174), Expect = 3e-12
Identities = 73/210 (34%), Positives = 97/210 (46%), Gaps = 32/210 (15%)
Query: 3 RSNSRSHSSR---SKSRSQSSSRS-RSRSHSRKKRYRSRSRTY---SRSRSRD---RMYS 52
RS S H SR S+SRS++ RS +S+SH + R RSRSR SRSRS+ R S
Sbjct: 1828 RSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVS 1887
Query: 53 RDYR----------RDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRS 102
++ R R+ + R R R R R H RR SRS
Sbjct: 1888 KEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS-----RRRRSRS 1942
Query: 103 PRRGRSRSRSPKRRS-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSP--YSKSPVSKRRGS 159
R RS S SP RRS S+RSR+ SRRS SR R+ S RS +P S++P +RR
Sbjct: 1943 VGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSR 2002
Query: 160 QEKQTKKAEGEP----QEESPLKSKSQEEP 185
+ + P + +PL+ + P
Sbjct: 2003 SVVRRRSFSISPVRLRRSRTPLRRRFSRSP 2032
Score = 65.5 bits (158), Expect = 2e-10
Identities = 67/196 (34%), Positives = 91/196 (46%), Gaps = 30/196 (15%)
Query: 4 SNSRSHSSRSKSRSQSSSRSR-----SRSHSRKKRYRS---RSRTYSRSRSRDRMYSRDY 55
S+ RS S RSKS S +SR SRS +RK+ +S RS+T SRSRSR R S
Sbjct: 1820 SSLRSRSKRSKS---SEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRS 1876
Query: 56 RRDYRNNRGM---RRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRS 112
R R R + +R + R + + R + V R SR+P R RSRS +
Sbjct: 1877 RSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTV--RARSRTPSR-RSRSHT 1933
Query: 113 PKRRSVS-------------SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGS 159
P RR S S+RSR+ SRRS SR R+ S RS +P +S RR
Sbjct: 1934 PSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSR 1993
Query: 160 QEKQTKKAEGEPQEES 175
+ +++ + S
Sbjct: 1994 TPSRRRRSRSVVRRRS 2009
Score = 59.3 bits (142), Expect = 1e-08
Identities = 65/222 (29%), Positives = 91/222 (40%), Gaps = 14/222 (6%)
Query: 98 RHSRSPRRGRSRSRSPKRRSVSSQ-RSRSRSRRSYRSSRS-PRSSSSRSSSPYSKSPVSK 155
R S R R+R RS K +S SQ RSRSRSRR RSSRS +S RS S + K
Sbjct: 1837 RKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPK 1896
Query: 156 RRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLS 215
R ++ +K ++++S+ + + H PS + S I P
Sbjct: 1897 HRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRR 1956
Query: 216 AYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSV 275
+ S RS +PS + PS+ S T TPS+ S + S R V
Sbjct: 1957 SRTPSRRS-RTPSRRSRTPSRRS--------RTPSRRSRTPSRRSRT--PSRRRRSRSVV 2005
Query: 276 GNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRS 317
S SP + P RR +++ + R RGRS
Sbjct: 2006 RRRSFSISPVRLRR-SRTPLRRRFSRSPIRRKRSRSSERGRS 2046
Score = 52.0 bits (123), Expect = 2e-06
Identities = 58/195 (29%), Positives = 80/195 (41%), Gaps = 44/195 (22%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTY-SRSRSRDRMY-SRDYRRDYR 60
++ +R + K R SS RSRS+ S+ ++SR RT SRSR+R R S+ +R R
Sbjct: 1805 KNKNRDKGEKEKKRD-SSLRSRSK-RSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTR 1862
Query: 61 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGR--------SRSRS 112
+ RR RR SRS + R R RS
Sbjct: 1863 SRSRSRR----------------------------RRRSSRSRSKSRGRRSVSKEKRKRS 1894
Query: 113 PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKS--PVSKRRGSQEKQTKKAEGE 170
PK RS S +R R RS S R +R + SR+ S S+S P +RR + +
Sbjct: 1895 PKHRSKSRERKRKRS--SSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSIS 1952
Query: 171 PQEESPLKSKSQEEP 185
P S S+ P
Sbjct: 1953 PSRRSRTPSRRSRTP 1967
Score = 41.2 bits (95), Expect = 0.004
Identities = 74/314 (23%), Positives = 114/314 (36%), Gaps = 39/314 (12%)
Query: 466 VERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTF 525
+E P KD H + N+ V K+T+ P VK L L +E S
Sbjct: 1655 IEGPLPAKDIHLDLPSNNN--LVSKDTEEPLPVKES--------DQTLAALLSPKESSGG 1704
Query: 526 REESPLRIKMIASDSHRP-------EVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVK 578
+E P K DS E L + P+ D R SL + + L V
Sbjct: 1705 EKEVPPPPKETLPDSGFSANIEDINEADL-VRPLLPKDMERLTSL-RAGIEGPLLASDVG 1762
Query: 579 KEQEFRSIFDHIKLPQASKSTSESFIQHIVSL-VHHVKEQYFKSAAMTLNERFTSYQKAT 637
+++ S +AS+S+SE + + + V E+ K+ E+ +
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 638 EEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDR 697
S R KS E R S S R R + K ++ + + R S R R
Sbjct: 1823 RSRSKRSKSSEHKSRKRTSESRSRARKRSS------KSKSHRSQTRSRSRSRRRR----R 1872
Query: 698 RRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPS 757
+ RSK RG R S K++++PK ++S + K KR + A
Sbjct: 1873 SSRSRSKSRG-----RRSVSKEKRKRSPK----HRSKSRERKRKRSSSRDNRKTVRARSR 1923
Query: 758 SPSSREEKESKKER 771
+PS R + R
Sbjct: 1924 TPSRRSRSHTPSRR 1937
Score = 40.0 bits (92), Expect = 0.009
Identities = 54/234 (23%), Positives = 87/234 (37%), Gaps = 6/234 (2%)
Query: 109 RSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKS-PVSKRRGSQEKQTKKA 167
RSRS KR S +SR R+ S RS RSS S+S ++S S+RR + K+
Sbjct: 1823 RSRS-KRSKSSEHKSRKRTSES-RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKS 1880
Query: 168 EGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSP 227
G + +S + + E S N+ + + P + ++P
Sbjct: 1881 RGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRS 1940
Query: 228 SPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQN 287
+ +S S S + T TPS+ S + S +PS+
Sbjct: 1941 RSVGR--RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRR 1998
Query: 288 SPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQ-ETAKTGKFLKRFTD 340
+ RRS + + R R R S P + +++ G+ KR TD
Sbjct: 1999 RRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTD 2052
Score = 35.4 bits (80), Expect = 0.23
Identities = 26/144 (18%), Positives = 57/144 (39%), Gaps = 3/144 (2%)
Query: 634 QKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRH 693
++A+E S + EI ++ + +K+ E+ K ++ + R S++ +
Sbjct: 1777 ERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHK- 1835
Query: 694 DIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSS 753
R+R S+ R + S+ S + + + +S + SK + + S+
Sbjct: 1836 --SRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKR 1893
Query: 754 ASPSSPSSREEKESKKEREEEFKT 777
+ SRE K + + KT
Sbjct: 1894 SPKHRSKSRERKRKRSSSRDNRKT 1917
Score = 35.4 bits (80), Expect = 0.23
Identities = 33/149 (22%), Positives = 52/149 (34%), Gaps = 15/149 (10%)
Query: 674 KEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKS 733
K+ ++K K D + D + RSK S+ S + + K + KS
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKS 1856
Query: 734 YKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRP 793
++ ++ + R SS S S S KE +K + E K R
Sbjct: 1857 HRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERK---------RK 1907
Query: 794 RGTFHDDRDDGVDYWAKRGRGRGTFQRGR 822
R + D+R R R R +R R
Sbjct: 1908 RSSSRDNRK------TVRARSRTPSRRSR 1930
Score = 34.3 bits (77), Expect = 0.51
Identities = 33/131 (25%), Positives = 57/131 (43%), Gaps = 6/131 (4%)
Query: 125 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEE 184
SR R P S K +K++ ++++ KK + +P EES K+KS ++
Sbjct: 87 SRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQP-EESESKTKSHDD 145
Query: 185 PKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAP 244
E D D ++ SA + ++ A+ S + SP+ + PP S S+
Sbjct: 146 GNIDLESDSFLKFD--SEPSAVALEL--PTRAFGPS-ETNESPAVVLEPPVVSMEVSEPH 200
Query: 245 MLSTVHSAKNT 255
+L T+ A T
Sbjct: 201 ILETLKPATKT 211
Score = 31.6 bits (70), Expect = 3.3
Identities = 44/181 (24%), Positives = 75/181 (41%), Gaps = 22/181 (12%)
Query: 422 ATASHRNTEEEGLKYKSKVSLKGNRESD---------GFREEK--NYKLKETGYVVERPS 470
A AS R+ E + K + L G +++ G R+ + + + T + + S
Sbjct: 49 AAASARSLPNEEIVQKIEEVLSGVLDTELRYKPDLKEGSRKSRCVSVQTDPTDEIPTKKS 108
Query: 471 TTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAR---EKSTFRE 527
KHK + K ++ KK + PE+ +S K K D + L + + E S
Sbjct: 109 KKHKKHKNKKKKKKKEKEKKYKRQPEESES-KTKSHDDGNIDLESDSFLKFDSEPSAVAL 167
Query: 528 ESPLRIKMIASDSHRPEVKLKMAPVPLDDSN-------RPASLTKDRLLASTLVHSVKKE 580
E P R + + P V L+ V ++ S +PA+ T + + ST V S + E
Sbjct: 168 ELPTRAFGPSETNESPAVVLEPPVVSMEVSEPHILETLKPATKTAELSVVSTSVISEQSE 227
Query: 581 Q 581
Q
Sbjct: 228 Q 228
Score = 31.2 bits (69), Expect = 4.4
Identities = 16/75 (21%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Query: 673 FKEENQKGDKKLRCDSA--DLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKE 730
+K + ++G +K RC S D +I ++ ++ K+ + K ++ +K ++ P++ +
Sbjct: 79 YKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESES 138
Query: 731 YKSYKDDSKHKREQD 745
DD E D
Sbjct: 139 KTKSHDDGNIDLESD 153
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 78.6 bits (192), Expect = 2e-14
Identities = 78/217 (35%), Positives = 104/217 (47%), Gaps = 22/217 (10%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRS-RSRTYSRSRSRDRMYSRDYRRDYR- 60
RS SRS R SRS+S SR R RS S++KR RS + R+ SR R R R SRD R+ R
Sbjct: 1862 RSRSRSRRRRRSSRSRSKSRGR-RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRA 1920
Query: 61 -----NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP-RRGRS---RSR 111
+ R R R R GR P R SR+P RR R+ RSR
Sbjct: 1921 RSRTPSRRSRSHTPSRRRRSRSV-----GRRRSFSISP---SRRSRTPSRRSRTPSRRSR 1972
Query: 112 SPKRRS-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGE 170
+P RRS S+RSR+ SRRS SR RS S +S SPV RR + + +
Sbjct: 1973 TPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSP 2032
Query: 171 PQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATS 207
+ + S+ PK + D ++ + E K++A +
Sbjct: 2033 IRRKRSRSSERGRSPKRLTDLDKAQLL-EIAKANAAA 2068
Score = 71.6 bits (174), Expect = 3e-12
Identities = 73/210 (34%), Positives = 97/210 (46%), Gaps = 32/210 (15%)
Query: 3 RSNSRSHSSR---SKSRSQSSSRS-RSRSHSRKKRYRSRSRTY---SRSRSRD---RMYS 52
RS S H SR S+SRS++ RS +S+SH + R RSRSR SRSRS+ R S
Sbjct: 1828 RSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVS 1887
Query: 53 RDYR----------RDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRS 102
++ R R+ + R R R R R H RR SRS
Sbjct: 1888 KEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS-----RRRRSRS 1942
Query: 103 PRRGRSRSRSPKRRS-VSSQRSRSRSRRSYRSSRSPRSSSSRSSSP--YSKSPVSKRRGS 159
R RS S SP RRS S+RSR+ SRRS SR R+ S RS +P S++P +RR
Sbjct: 1943 VGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSR 2002
Query: 160 QEKQTKKAEGEP----QEESPLKSKSQEEP 185
+ + P + +PL+ + P
Sbjct: 2003 SVVRRRSFSISPVRLRRSRTPLRRRFSRSP 2032
Score = 65.5 bits (158), Expect = 2e-10
Identities = 67/196 (34%), Positives = 91/196 (46%), Gaps = 30/196 (15%)
Query: 4 SNSRSHSSRSKSRSQSSSRSR-----SRSHSRKKRYRS---RSRTYSRSRSRDRMYSRDY 55
S+ RS S RSKS S +SR SRS +RK+ +S RS+T SRSRSR R S
Sbjct: 1820 SSLRSRSKRSKS---SEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRS 1876
Query: 56 RRDYRNNRGM---RRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRS 112
R R R + +R + R + + R + V R SR+P R RSRS +
Sbjct: 1877 RSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTV--RARSRTPSR-RSRSHT 1933
Query: 113 PKRRSVS-------------SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGS 159
P RR S S+RSR+ SRRS SR R+ S RS +P +S RR
Sbjct: 1934 PSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSR 1993
Query: 160 QEKQTKKAEGEPQEES 175
+ +++ + S
Sbjct: 1994 TPSRRRRSRSVVRRRS 2009
Score = 59.3 bits (142), Expect = 1e-08
Identities = 65/222 (29%), Positives = 91/222 (40%), Gaps = 14/222 (6%)
Query: 98 RHSRSPRRGRSRSRSPKRRSVSSQ-RSRSRSRRSYRSSRS-PRSSSSRSSSPYSKSPVSK 155
R S R R+R RS K +S SQ RSRSRSRR RSSRS +S RS S + K
Sbjct: 1837 RKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPK 1896
Query: 156 RRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLS 215
R ++ +K ++++S+ + + H PS + S I P
Sbjct: 1897 HRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRR 1956
Query: 216 AYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSV 275
+ S RS +PS + PS+ S T TPS+ S + S R V
Sbjct: 1957 SRTPSRRS-RTPSRRSRTPSRRS--------RTPSRRSRTPSRRSRT--PSRRRRSRSVV 2005
Query: 276 GNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRS 317
S SP + P RR +++ + R RGRS
Sbjct: 2006 RRRSFSISPVRLRR-SRTPLRRRFSRSPIRRKRSRSSERGRS 2046
Score = 52.0 bits (123), Expect = 2e-06
Identities = 58/195 (29%), Positives = 80/195 (41%), Gaps = 44/195 (22%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTY-SRSRSRDRMY-SRDYRRDYR 60
++ +R + K R SS RSRS+ S+ ++SR RT SRSR+R R S+ +R R
Sbjct: 1805 KNKNRDKGEKEKKRD-SSLRSRSK-RSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTR 1862
Query: 61 NNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGR--------SRSRS 112
+ RR RR SRS + R R RS
Sbjct: 1863 SRSRSRR----------------------------RRRSSRSRSKSRGRRSVSKEKRKRS 1894
Query: 113 PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKS--PVSKRRGSQEKQTKKAEGE 170
PK RS S +R R RS S R +R + SR+ S S+S P +RR + +
Sbjct: 1895 PKHRSKSRERKRKRS--SSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSIS 1952
Query: 171 PQEESPLKSKSQEEP 185
P S S+ P
Sbjct: 1953 PSRRSRTPSRRSRTP 1967
Score = 41.2 bits (95), Expect = 0.004
Identities = 74/314 (23%), Positives = 114/314 (36%), Gaps = 39/314 (12%)
Query: 466 VERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTF 525
+E P KD H + N+ V K+T+ P VK L L +E S
Sbjct: 1655 IEGPLPAKDIHLDLPSNNN--LVSKDTEEPLPVKES--------DQTLAALLSPKESSGG 1704
Query: 526 REESPLRIKMIASDSHRP-------EVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVK 578
+E P K DS E L + P+ D R SL + + L V
Sbjct: 1705 EKEVPPPPKETLPDSGFSANIEDINEADL-VRPLLPKDMERLTSL-RAGIEGPLLASDVG 1762
Query: 579 KEQEFRSIFDHIKLPQASKSTSESFIQHIVSL-VHHVKEQYFKSAAMTLNERFTSYQKAT 637
+++ S +AS+S+SE + + + V E+ K+ E+ +
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 638 EEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDR 697
S R KS E R S S R R + K ++ + + R S R R
Sbjct: 1823 RSRSKRSKSSEHKSRKRTSESRSRARKRSS------KSKSHRSQTRSRSRSRRRR----R 1872
Query: 698 RRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPS 757
+ RSK RG R S K++++PK ++S + K KR + A
Sbjct: 1873 SSRSRSKSRG-----RRSVSKEKRKRSPK----HRSKSRERKRKRSSSRDNRKTVRARSR 1923
Query: 758 SPSSREEKESKKER 771
+PS R + R
Sbjct: 1924 TPSRRSRSHTPSRR 1937
Score = 40.0 bits (92), Expect = 0.009
Identities = 54/234 (23%), Positives = 87/234 (37%), Gaps = 6/234 (2%)
Query: 109 RSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKS-PVSKRRGSQEKQTKKA 167
RSRS KR S +SR R+ S RS RSS S+S ++S S+RR + K+
Sbjct: 1823 RSRS-KRSKSSEHKSRKRTSES-RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKS 1880
Query: 168 EGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSP 227
G + +S + + E S N+ + + P + ++P
Sbjct: 1881 RGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRS 1940
Query: 228 SPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQN 287
+ +S S S + T TPS+ S + S +PS+
Sbjct: 1941 RSVGR--RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRR 1998
Query: 288 SPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQ-ETAKTGKFLKRFTD 340
+ RRS + + R R R S P + +++ G+ KR TD
Sbjct: 1999 RRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTD 2052
Score = 35.4 bits (80), Expect = 0.23
Identities = 26/144 (18%), Positives = 57/144 (39%), Gaps = 3/144 (2%)
Query: 634 QKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRH 693
++A+E S + EI ++ + +K+ E+ K ++ + R S++ +
Sbjct: 1777 ERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHK- 1835
Query: 694 DIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSS 753
R+R S+ R + S+ S + + + +S + SK + + S+
Sbjct: 1836 --SRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKR 1893
Query: 754 ASPSSPSSREEKESKKEREEEFKT 777
+ SRE K + + KT
Sbjct: 1894 SPKHRSKSRERKRKRSSSRDNRKT 1917
Score = 35.4 bits (80), Expect = 0.23
Identities = 33/149 (22%), Positives = 52/149 (34%), Gaps = 15/149 (10%)
Query: 674 KEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKS 733
K+ ++K K D + D + RSK S+ S + + K + KS
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKS 1856
Query: 734 YKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRP 793
++ ++ + R SS S S S KE +K + E K R
Sbjct: 1857 HRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERK---------RK 1907
Query: 794 RGTFHDDRDDGVDYWAKRGRGRGTFQRGR 822
R + D+R R R R +R R
Sbjct: 1908 RSSSRDNRK------TVRARSRTPSRRSR 1930
Score = 34.3 bits (77), Expect = 0.51
Identities = 33/131 (25%), Positives = 57/131 (43%), Gaps = 6/131 (4%)
Query: 125 SRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEE 184
SR R P S K +K++ ++++ KK + +P EES K+KS ++
Sbjct: 87 SRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQP-EESESKTKSHDD 145
Query: 185 PKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAP 244
E D D ++ SA + ++ A+ S + SP+ + PP S S+
Sbjct: 146 GNIDLESDSFLKFD--SEPSAVALEL--PTRAFGPS-ETNESPAVVLEPPVVSMEVSEPH 200
Query: 245 MLSTVHSAKNT 255
+L T+ A T
Sbjct: 201 ILETLKPATKT 211
Score = 31.6 bits (70), Expect = 3.3
Identities = 44/181 (24%), Positives = 75/181 (41%), Gaps = 22/181 (12%)
Query: 422 ATASHRNTEEEGLKYKSKVSLKGNRESD---------GFREEK--NYKLKETGYVVERPS 470
A AS R+ E + K + L G +++ G R+ + + + T + + S
Sbjct: 49 AAASARSLPNEEIVQKIEEVLSGVLDTELRYKPDLKEGSRKSRCVSVQTDPTDEIPTKKS 108
Query: 471 TTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAR---EKSTFRE 527
KHK + K ++ KK + PE+ +S K K D + L + + E S
Sbjct: 109 KKHKKHKNKKKKKKKEKEKKYKRQPEESES-KTKSHDDGNIDLESDSFLKFDSEPSAVAL 167
Query: 528 ESPLRIKMIASDSHRPEVKLKMAPVPLDDSN-------RPASLTKDRLLASTLVHSVKKE 580
E P R + + P V L+ V ++ S +PA+ T + + ST V S + E
Sbjct: 168 ELPTRAFGPSETNESPAVVLEPPVVSMEVSEPHILETLKPATKTAELSVVSTSVISEQSE 227
Query: 581 Q 581
Q
Sbjct: 228 Q 228
Score = 31.2 bits (69), Expect = 4.4
Identities = 16/75 (21%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Query: 673 FKEENQKGDKKLRCDSA--DLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKE 730
+K + ++G +K RC S D +I ++ ++ K+ + K ++ +K ++ P++ +
Sbjct: 79 YKPDLKEGSRKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESES 138
Query: 731 YKSYKDDSKHKREQD 745
DD E D
Sbjct: 139 KTKSHDDGNIDLESD 153
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 75.9 bits (185), Expect = 2e-13
Identities = 63/149 (42%), Positives = 70/149 (46%), Gaps = 29/149 (19%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
RS SRS SRS SRS S S SRSRS RSRSR+ S S+SR R SR+
Sbjct: 203 RSKSRSSHSRSSSRSSSPSSSRSRS-------RSRSRSSSSSQSRSRSSSRE-------- 247
Query: 63 RGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWN--RRHSRSPRRGRSRSRSPKRRSVSS 120
R R RG R HRG P S SP R R RSRS S
Sbjct: 248 ---------RSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDR 298
Query: 121 QRSRSRSR---RSYRSSRSPRSSSSRSSS 146
++ R+RSR R +RSS S SRSSS
Sbjct: 299 KKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
Score = 52.8 bits (125), Expect = 1e-06
Identities = 36/93 (38%), Positives = 47/93 (50%), Gaps = 9/93 (9%)
Query: 100 SRSPRRGRSRSRSPKRRSVSSQ---------RSRSRSRRSYRSSRSPRSSSSRSSSPYSK 150
S SP RSRSRS R S SSQ RSRSR +S SSRS R SSS YS
Sbjct: 217 SSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSS 276
Query: 151 SPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQE 183
S S R + +++ + +++ +S+S E
Sbjct: 277 SSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPE 309
Score = 49.7 bits (117), Expect = 1e-05
Identities = 49/218 (22%), Positives = 85/218 (38%), Gaps = 12/218 (5%)
Query: 627 NERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDK-KLR 685
N + +++ E+ + + +R + P+++ K E ++E++ K KL
Sbjct: 111 NVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLD 170
Query: 686 CDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQD 745
D + D+ + + S+E DS + + SR + ++ +S S R +
Sbjct: 171 EDEDEDDADLSKYNLDASEEE-DSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRS 229
Query: 746 HSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGV 805
SRSSSSS S S SSRE S+ + H G S PR +
Sbjct: 230 RSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHR--------GSSSPRKRSYSSSSSSP 281
Query: 806 DYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQG 843
+ KR R R + R + + SP+ H G
Sbjct: 282 ERNRKRSRSRSSSSGDRKK--RRTRSRSPERRHRSSSG 317
Score = 47.4 bits (111), Expect = 6e-05
Identities = 35/87 (40%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
Query: 101 RSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQ 160
+S RR RS+SRS RS SS+ S S RS SRS SSSS+S S S S+ RGS+
Sbjct: 197 KSNRRSRSKSRSSHSRS-SSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSK 255
Query: 161 EKQTKKA---EGEPQEESPLKSKSQEE 184
+ + ++ P++ S S S E
Sbjct: 256 SRSSSRSHRGSSSPRKRSYSSSSSSPE 282
Score = 47.4 bits (111), Expect = 6e-05
Identities = 41/124 (33%), Positives = 51/124 (41%), Gaps = 1/124 (0%)
Query: 85 RYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRS 144
R R R +R SRS SRSRS + RS SS S+SRSR S R R S SRS
Sbjct: 200 RRSRSKSRSSHSRSSSRSSSPSSSRSRS-RSRSRSSSSSQSRSRSSSRERSRSRGSKSRS 258
Query: 145 SSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSS 204
SS + S R+ S + E + S S + K E + S
Sbjct: 259 SSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGS 318
Query: 205 ATSG 208
+ SG
Sbjct: 319 SHSG 322
Score = 43.5 bits (101), Expect = 8e-04
Identities = 54/193 (27%), Positives = 82/193 (42%), Gaps = 22/193 (11%)
Query: 143 RSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNK 202
R Y V +E + K++EGE ++E SK + D E + + ++N
Sbjct: 129 RKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYK---LDEDEDEDDADLSKYNL 185
Query: 203 SSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHS---AKNTPSQH 259
++ D S S R S S + S+SSS S +P S S ++++ S
Sbjct: 186 DASEEED-----SNKKKSNRRSRSKS--RSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQ 238
Query: 260 SHSIQHSPERSGS-GSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSS 318
S S S ERS S GS SSR +SP +RS + + + R SR RSS
Sbjct: 239 SRSRSSSRERSRSRGSKSRSSSRSHRGSSSP-----RKRSYSSSSSSPERNRKRSRSRSS 293
Query: 319 FYPDGGDQETAKT 331
GD++ +T
Sbjct: 294 ---SSGDRKKRRT 303
Score = 42.7 bits (99), Expect = 0.001
Identities = 40/131 (30%), Positives = 53/131 (40%), Gaps = 8/131 (6%)
Query: 112 SPKRRSVSSQRSRSRSRRSYRSSRS--PRSSSSRSSSPYSKSPVSKRRG-SQEKQTKKAE 168
S K++S RS+SRS S SSRS P SS SRS S S S+ R S ++ ++
Sbjct: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSR 252
Query: 169 GEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPS 228
G S + P+ S S + K S + S+ D R S S
Sbjct: 253 GSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSS-----SSGDRKKRRTRSRS 307
Query: 229 PIATPPSQSSS 239
P S S S
Sbjct: 308 PERRHRSSSGS 318
Score = 41.2 bits (95), Expect = 0.004
Identities = 39/154 (25%), Positives = 59/154 (38%), Gaps = 13/154 (8%)
Query: 119 SSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLK 178
+S+ S ++S R SRS SS SS S SP S R S+ + + + + S +
Sbjct: 187 ASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSR 246
Query: 179 SKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSS 238
+S+ S + S + G P +Y +S SP + S+SS
Sbjct: 247 ERSR-----------SRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSR--SRSS 293
Query: 239 SCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS 272
S D T + + S HS RS S
Sbjct: 294 SSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSS 327
Score = 37.0 bits (84), Expect = 0.079
Identities = 34/142 (23%), Positives = 53/142 (37%), Gaps = 12/142 (8%)
Query: 638 EEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDR 697
EE S ++KS R S H+R + + + R S+
Sbjct: 190 EEDSNKKKSNRRSRSKSRS-----SHSRSSSRSSSPSSSRSRSRSRSRSSSSS-----QS 239
Query: 698 RRKERSKERGDSKGSRESSGSRKQEKTPKDYK-EYKSYKDDSKHKREQDHSRSSSSSASP 756
R + S+ER S+GS+ S SR + K Y S + R++ SR SSSS
Sbjct: 240 RSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSR-SSSSGDR 298
Query: 757 SSPSSREEKESKKEREEEFKTH 778
+R ++ R +H
Sbjct: 299 KKRRTRSRSPERRHRSSSGSSH 320
Score = 30.8 bits (68), Expect = 5.7
Identities = 25/57 (43%), Positives = 34/57 (59%), Gaps = 10/57 (17%)
Query: 3 RSNSRSHSS------RSKSRSQSS---SRSRSRSHSRKKRYRSRS-RTYSRSRSRDR 49
RS S S SS RS+SRS SS + R+RS S ++R+RS S ++S SRS +
Sbjct: 272 RSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSK 328
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 75.1 bits (183), Expect = 3e-13
Identities = 68/214 (31%), Positives = 94/214 (43%), Gaps = 21/214 (9%)
Query: 3 RSNSRSHS---SRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDY 59
R+ SRS ++ K S +R RSRS R +R RSRT+ R RSR + Y R ++Y
Sbjct: 541 RAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRV--RSRTHDRDRSRSKEYHRYREQEY 598
Query: 60 RNNRGMRRPYGYR---GRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRR 116
R RG R R GR R + R R R R+ R S+S K
Sbjct: 599 R-RRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKEN 657
Query: 117 SVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGS------QEKQTKKAEGE 170
S S +R S+SR S+ S + R SP+SK S + + K+ +K
Sbjct: 658 SESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSS 717
Query: 171 PQEESPLKSKSQE-----EPKDTFEHDPSESIDE 199
++E+ KSK QE E F+H+ S DE
Sbjct: 718 VEKENQ-KSKGQENDHVHEKNKKFDHESSPGTDE 750
Score = 66.2 bits (160), Expect = 1e-10
Identities = 121/618 (19%), Positives = 221/618 (35%), Gaps = 89/618 (14%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNR 63
S+S S S S S S S + +S RKK++R SR + + + + + + +
Sbjct: 204 SDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAEN 263
Query: 64 GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSP--------KR 115
+P R R+ P + + ++ R R R +P +R
Sbjct: 264 LEAQPQS-TVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQR 322
Query: 116 RSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA-------E 168
R + ++ R R R R+P S SR S++P R+ Q Q + +
Sbjct: 323 RLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIK 382
Query: 169 GEPQEESPLKSKSQ-----EEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRS 223
G+ E + +K + +E K T + SES + N+ D
Sbjct: 383 GDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKD-------------- 428
Query: 224 PHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYS 283
H + ++S D AK+ S S ER S+++
Sbjct: 429 -HKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKER---------DSKHN 478
Query: 284 PSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEES 343
++ + R S+GR ++++ GK +R +E
Sbjct: 479 RNE-------------------EKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEK 519
Query: 344 RVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEET 403
L + N D SKEK RA+ + D GK +N + +
Sbjct: 520 SKQLESKSNEHDHSKSKEKDR---RAQSRSRE-------CDITKGKHSYNSRTRERSRSR 569
Query: 404 EDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETG 463
+ R+ R S D+ +S + HR E+E + + + + R G K+ + +
Sbjct: 570 DRSRRVR-SRTHDRDRSRSKEYHRYREQE-YRRRGRSRSRERRTPPGRSRSKDRRRR--- 624
Query: 464 YVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKS 523
R S + ++ + + +N ++ ++ S + SE K ++ S + + ++REK
Sbjct: 625 ---RRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKK 681
Query: 524 TFREESPL-RIKMIASDSHRPEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQE 582
R++SP +IK + D+ LK S+ K + + VH K+
Sbjct: 682 ADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKK-- 739
Query: 583 FRSIFDHIKLPQASKSTS 600
FDH P + S
Sbjct: 740 ----FDHESSPGTDEDKS 753
Score = 65.5 bits (158), Expect = 2e-10
Identities = 134/667 (20%), Positives = 249/667 (37%), Gaps = 109/667 (16%)
Query: 113 PKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQ 172
PK + ++ R +S S SS S SSS S S S S + E+++KK + + +
Sbjct: 179 PKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQS---SSDSSDSESATEEKSKKRKKKHR 235
Query: 173 EESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIAT 232
+ S K +++ K + + SES E N + + P + P P + +
Sbjct: 236 KNSRKHKKEKKKRKKSKKSASSESEAE-NLEAQPQSTVRP-----EEIPPIPENRFLMRK 289
Query: 233 PPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHS--PERSGSGSVGNGSSRYSPSQNSPI 290
P ++ N P+ S Q RSG G G RY
Sbjct: 290 SPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRY-------- 341
Query: 291 HHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDR 350
R+P+++ R R R S P QE + + RV +R
Sbjct: 342 ------RTPSRS-------RSRDRFRRSETPPHWRQEMQRA---------QRMRVSSGER 379
Query: 351 GNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQFR 410
DK E E R+ ++++ D+ + ES +K N+ E
Sbjct: 380 WIKGDKSELNEI-KENQRSPVRVKERKITDHRNVSESPNRK-NEKE-------------- 423
Query: 411 KSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPS 470
K V + S RN+E++ KYK+KV + +S +EK S
Sbjct: 424 KKVKDHKSNSKERDIRRNSEKDD-KYKNKVKKRAKSKSRSKSKEK--------------S 468
Query: 471 TTKDKHKEEDKNSE-RITVKKETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREES 529
+K++ + ++N E R+ + + + E VK ++ K D++ K R S
Sbjct: 469 KSKERDSKHNRNEEKRMRSRSKGRDHENVKEKE------------KQSDSKGKDQERSRS 516
Query: 530 PLRIKMIASDSHRPE-VKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFD 588
+ K + S S+ + K K +R +TK + ++ + ++ RS
Sbjct: 517 KEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRD-RSRRV 575
Query: 589 HIKLPQASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPE 648
+ +S S+ + H +EQ ++ R S + R +S +
Sbjct: 576 RSRTHDRDRSRSKEY--------HRYREQEYR-------RRGRSRSRERRTPPGRSRSKD 620
Query: 649 IHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGD 708
RR S S+ R+ ++ +++ +E++ +K +S ++R +S++
Sbjct: 621 RRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSES-------EKRMYSKSRDHNS 673
Query: 709 SKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESK 768
S SRE R Q K + + + S + ++ + SS + S +E +
Sbjct: 674 SNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHV 733
Query: 769 KEREEEF 775
E+ ++F
Sbjct: 734 HEKNKKF 740
Score = 63.9 bits (154), Expect = 6e-10
Identities = 66/214 (30%), Positives = 93/214 (43%), Gaps = 36/214 (16%)
Query: 3 RSNSRSHSSRSKSRSQSSSRS----RSRSHSRKKRYRSRSRTYSRSRSRD---RMYSRDY 55
RS R H + + QS S+ RSRS + K+ S+S + S+S++ R SR
Sbjct: 488 RSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSR 547
Query: 56 R------------RDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP 103
R +R R R R + YHR YR RR RS
Sbjct: 548 ECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHR--YREQEYRRRGRSR 605
Query: 104 RR------GRSRSRSPKRR---SVSSQR--SRSRSRRSYRSSRSPRSSSSRSSSPYSKSP 152
R GRSRS+ +RR S SS+R S+SR++ YR+ S +SS + +S K
Sbjct: 606 SRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQES-KSSHRKENSESEKRM 664
Query: 153 VSKRR---GSQEKQTKKAEGEPQEESPLKSKSQE 183
SK R S + KKA+ + S +K SQ+
Sbjct: 665 YSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQD 698
Score = 57.0 bits (136), Expect = 7e-08
Identities = 56/217 (25%), Positives = 97/217 (44%), Gaps = 36/217 (16%)
Query: 3 RSNSRSHSS-RSKSRSQSS-----------SRSRSRSH----SRKKRYRSRSRTYSRSRS 46
+S SRS S +SKS+ + S SRS+ R H ++K+ S+ + RSRS
Sbjct: 457 KSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRS 516
Query: 47 RDR---MYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSP 103
+++ + S+ D+ ++ R R R +G + +SR+
Sbjct: 517 KEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGK-------------HSYNSRTR 563
Query: 104 RRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQ 163
R RSR RS + RS + R RSRS+ +R RS S ++P + R ++
Sbjct: 564 ERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRR 623
Query: 164 TKK-AEGEPQEESPLKSKSQ---EEPKDTFEHDPSES 196
++ + +EES ++K + +E K + + SES
Sbjct: 624 RRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSES 660
Score = 56.6 bits (135), Expect = 1e-07
Identities = 113/538 (21%), Positives = 183/538 (34%), Gaps = 85/538 (15%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHS--------------------------------- 29
R NSR H K R +S + S S +
Sbjct: 235 RKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKA 294
Query: 30 ----RKKRYRSRSRTYSRSRSRDRMYSRD--YRRDYRNNRGMRRPYGYRGRGRGYYQGGG 83
RK R R R R + S+ Y R R R +G R P YR R +
Sbjct: 295 DEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKG-RGPRRYRTPSRSRSR--- 350
Query: 84 GRYHRGGYRPVWNRRHSRSPRR-----------GRSRSRSPKRRSVSSQRSRSRSRRSYR 132
R+ R P W + R+ R +S K S R + R +R
Sbjct: 351 DRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHR 410
Query: 133 S-SRSPRSSSSRSSSPYSKSPVSK----RRGSQEKQTKKAEGEPQEESPLKSKSQEEPKD 187
+ S SP + + SK RR S++ K + + + +S +SKS+E+ K
Sbjct: 411 NVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKS 470
Query: 188 TFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLS 247
+E S + G ++N +S S + L
Sbjct: 471 KERDSKHNRNEEKRMRSRSKG------RDHENVKEKEKQSDSKGKDQERSRSKEKSKQL- 523
Query: 248 TVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQN 307
+K+ HS S + R+ S S ++ S NS R ++ + +
Sbjct: 524 ---ESKSNEHDHSKS-KEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRT 579
Query: 308 APRDESRGRSSFYPDGGDQETAKTGKFLKR-FTDEESRVFLLDRGNTRDKEASKEKGSEK 366
RD R RS Y +QE + G+ R R DR R S E+ +
Sbjct: 580 HDRD--RSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQ 637
Query: 367 GRAEGEWEDQEALDYFSDKESGKQKFNDSEGDDTEETEDYRQ---------FRKSVLADQ 417
R + ++ +QE+ + S +K S+ D + + R+ F K + Q
Sbjct: 638 SRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQ 697
Query: 418 GKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDK 475
++ +N E+E K +S V K N++S G + ++ + P T +DK
Sbjct: 698 DNELKSSMLKNKEDE--KIRSSVE-KENQKSKGQENDHVHEKNKKFDHESSPGTDEDK 752
Score = 46.2 bits (108), Expect = 1e-04
Identities = 98/474 (20%), Positives = 183/474 (38%), Gaps = 65/474 (13%)
Query: 430 EEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSERITVK 489
+EE ++KS S + SD + ++ + S T++K K+ K + + K
Sbjct: 185 KEEKKRHKSSSS-SSSSSSDSDSSSDSQSSSDSS---DSESATEEKSKKRKKKHRKNSRK 240
Query: 490 KETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREES--PL---RIKMIASDSHRPE 544
+ + ++ KS+K S +NL+A+ +ST R E P+ R M S E
Sbjct: 241 HKKEKKKRKKSKKSAS----SESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADE 296
Query: 545 VKLKMAPVPLD-----DSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKST 599
+ K + +++PAS + RLL + +K R + P S+S
Sbjct: 297 KERKNRERERERECNPPNSQPASYQR-RLLVTRSGRKIKGRGPRR-----YRTP--SRSR 348
Query: 600 SESFIQHIVSLVHHVKE-QYFKSAAMTLNERFTSYQKAT-EEHSTRQKSPEIHRRIDISP 657
S + + H +E Q + ++ ER+ K+ E Q+SP + +
Sbjct: 349 SRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSP-----VRVKE 403
Query: 658 STLRKHTRLA-GEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESS 716
+ H ++ R ++E + D K D+R + ++ K ++K + K ++ S
Sbjct: 404 RKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVK---KRAKSKS 460
Query: 717 GSRKQEKTPKDYKEYKSYKDDSKHKREQ-----------DHSRSSSSSASPSSPSSREEK 765
S+ +EK+ KS + DSKH R + DH S +E+
Sbjct: 461 RSKSKEKS-------KSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQER 513
Query: 766 ESKKEREEEFKT------HHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQ 819
KE+ ++ ++ H + KE A + +R R R +
Sbjct: 514 SRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSR 573
Query: 820 RGRGRFNFK---KSGSSPKWTHDKYQGDGIVED-EEETMENNEEKKDRRKEEKE 869
R R R + + +S ++ +Y+ G E T KDRR+ ++
Sbjct: 574 RVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRD 627
Score = 43.9 bits (102), Expect = 6e-04
Identities = 27/118 (22%), Positives = 49/118 (41%), Gaps = 9/118 (7%)
Query: 666 LAGEERVFKEENQKGD---------KKLRCDSADLRHDIDRRRKERSKERGDSKGSRESS 716
++G+E V + ENQK D + L C + + + K+R K S S S
Sbjct: 145 ISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDS 204
Query: 717 GSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEE 774
S ++ D + +S ++ KR++ H ++S + +K + E E E
Sbjct: 205 DSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAE 262
Score = 41.2 bits (95), Expect = 0.004
Identities = 46/215 (21%), Positives = 84/215 (39%), Gaps = 23/215 (10%)
Query: 674 KEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKS 733
K+E +K K S+ + S + DS+ + E ++++K K+ +++K
Sbjct: 184 KKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKK 243
Query: 734 YKDDSKHKREQDHSRSSSSS--ASPSSPSSREE------------KESKKEREEEFKTHH 779
K K ++ S S + + A P S EE K K E+E K
Sbjct: 244 EKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRE 303
Query: 780 EMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRG-----TFQRGRGRFNFKKSGSSP 834
+E S+P R V ++ +GRG T R R R F++S + P
Sbjct: 304 RERERECNPPNSQPASY---QRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPP 360
Query: 835 KWTHDKYQGDGI-VEDEEETMENNEEKKDRRKEEK 868
W + + + V E ++ ++ + + KE +
Sbjct: 361 HWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQ 395
Score = 34.3 bits (77), Expect = 0.51
Identities = 18/64 (28%), Positives = 31/64 (48%)
Query: 720 KQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHH 779
K + ++ K +KS S + D S S SS+ S S E++SKK +++ K
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSR 239
Query: 780 EMKE 783
+ K+
Sbjct: 240 KHKK 243
>gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]
Length = 282
Score = 75.1 bits (183), Expect = 3e-13
Identities = 70/180 (38%), Positives = 82/180 (45%), Gaps = 24/180 (13%)
Query: 3 RSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNN 62
RS S RS+SR S SRSRSRS R RY SRS YSRS Y +
Sbjct: 124 RSRSPRRRHRSRSRGPSCSRSRSRSRYRGSRY-SRS-PYSRS-------------PYSRS 168
Query: 63 RGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSR--SPRRGRSRSRSPKRRSVSS 120
R R PY Y GG Y GY N R+SR S R S RS S+
Sbjct: 169 RYSRSPYSRSRYRESRY--GGSHYSSSGYS---NSRYSRYHSSRSHSKSGSSTSSRSAST 223
Query: 121 QRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSP-VSKRRGSQEKQTKKAEGEPQEESPLKS 179
+S S +RRS SS S S SRSSS P VSKR+ ++K+ P+EE + S
Sbjct: 224 SKS-SSARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRSKRPPKSPEEEGQMSS 282
Score = 61.2 bits (147), Expect = 4e-09
Identities = 79/251 (31%), Positives = 104/251 (41%), Gaps = 23/251 (9%)
Query: 28 HSRKKRYRSRSRTYSRSRSRDRMYSRDYRR-DYRNNRGMRRPYGYRGRGRGYYQGGGGRY 86
H++ R + R + R ++D + D D R R YG R R GR
Sbjct: 50 HTKAPRGFAFVRFHDRRDAQDAEAAMDGAELDGRELRVQVARYGRRDLPRSRQGEPRGRS 109
Query: 87 HRGGY--RPVWNRRHSRSPRRG-RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSR 143
GGY R R SRSPRR RSRSR P S RSRSRSR YR SR RS SR
Sbjct: 110 RGGGYGRRSRSYGRRSRSPRRRHRSRSRGP-----SCSRSRSRSR--YRGSRYSRSPYSR 162
Query: 144 SSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKS 203
S PYS+S S+ S+ + + G S S S+ + S +KS
Sbjct: 163 S--PYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSR--------YSRYHSSRSHSKS 212
Query: 204 SATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSI 263
+++ S ++ RS S + S+SSS + +P V K+ S
Sbjct: 213 GSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSP--PRVSKRKSKSRSRSKRP 270
Query: 264 QHSPERSGSGS 274
SPE G S
Sbjct: 271 PKSPEEEGQMS 281
Score = 40.0 bits (92), Expect = 0.009
Identities = 60/222 (27%), Positives = 83/222 (37%), Gaps = 57/222 (25%)
Query: 98 RHSRSPRRGRSRSRSPKRRSVS-SQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 156
R + RGRSR RRS S +RSRS RR SR P S SRS S Y
Sbjct: 99 RSRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHRSRSRGPSCSRSRSRSRY-------- 150
Query: 157 RGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSA 216
RGS+ ++ P SP S
Sbjct: 151 RGSRYSRS------PYSRSPYSR-----------------------------------SR 169
Query: 217 YDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVG 276
Y RSP+S S S S + ++ +S ++ HS S + RS S S
Sbjct: 170 YS---RSPYSRSRYRESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKS 226
Query: 277 NGSSRYSPSQNSPIHHIPSR-RSPAKTIAPQNAPRDESRGRS 317
+ + R S++S + SR RS + T +P + +S+ RS
Sbjct: 227 SSARR---SKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRS 265
Score = 30.0 bits (66), Expect = 9.7
Identities = 37/142 (26%), Positives = 49/142 (34%), Gaps = 16/142 (11%)
Query: 633 YQKATEEHSTRQKSPEI-HRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADL 691
Y + + + R +SP HR PS R +R R + + S
Sbjct: 114 YGRRSRSYGRRSRSPRRRHRSRSRGPSCSRSRSR--SRYRGSRYSRSPYSRSPYSRSRYS 171
Query: 692 RHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKH-----KREQDH 746
R R R S+ G S S SR Y Y S + SK R
Sbjct: 172 RSPYSRSRYRESRYGGSHYSSSGYSNSR--------YSRYHSSRSHSKSGSSTSSRSAST 223
Query: 747 SRSSSSSASPSSPSSREEKESK 768
S+SSS+ S SS SR S+
Sbjct: 224 SKSSSARRSKSSSVSRSRSRSR 245
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 73.2 bits (178), Expect = 1e-12
Identities = 60/175 (34%), Positives = 77/175 (44%), Gaps = 16/175 (9%)
Query: 13 SKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYR 72
S RS S SRSRSRS ++R RSRSR SRSRSR SR R R R G +
Sbjct: 186 SHRRSYSGSRSRSRS---RRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRK 242
Query: 73 GRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYR 132
R + + R R + +S R RSRSRSPK +S+SRSR
Sbjct: 243 SRSKSKSKPKSDRGSHSHSRSRSKDEYEKS--RSRSRSRSPKENGKGDIKSKSRSR---- 296
Query: 133 SSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKD 187
S SRS+SP P R S + + + S +S+S+ +D
Sbjct: 297 -------SQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
Score = 71.2 bits (173), Expect = 4e-12
Identities = 63/180 (35%), Positives = 86/180 (47%), Gaps = 17/180 (9%)
Query: 99 HSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRG 158
+ R+ R + R+ RRS S RSRSRSRR RS RS RSS SRS S SKS R
Sbjct: 172 NGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRS-RSRRSSRSRSRS-ISKSRSRSRSR 229
Query: 159 SQEKQTKKAEGEPQEESPLKSKSQEEPKD---TFEHDPSESIDEFNKSSATSGDIWP--- 212
S+ + +++G +SKS+ +PK + H S S DE+ KS + S P
Sbjct: 230 SKGRSRSRSKGRKS-----RSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKEN 284
Query: 213 ---GLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPER 269
+ + S S SP+ PPS++ S S P +T S + S+ S S S R
Sbjct: 285 GKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSK-SRSRSRSSSR 343
Score = 63.2 bits (152), Expect = 1e-09
Identities = 58/154 (37%), Positives = 75/154 (48%), Gaps = 30/154 (19%)
Query: 3 RSNSRSHS-SRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRR---D 58
R +SRS S S SKSRS+S SRS+ RS SR K +SRS++ S+ +S +S R +
Sbjct: 209 RRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDE 268
Query: 59 YRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGRSRSRSP----- 113
Y +R R + G+G + S+S R +SRS SP
Sbjct: 269 YEKSRSRSRSRSPKENGKGDIK-------------------SKSRSRSQSRSNSPLPVPP 309
Query: 114 -KRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSS 146
K RSVS R+ SR R SRS S SRSSS
Sbjct: 310 SKARSVSPPPKRATSRSRSR-SRSKSRSRSRSSS 342
Score = 48.1 bits (113), Expect = 3e-05
Identities = 48/164 (29%), Positives = 64/164 (39%), Gaps = 40/164 (24%)
Query: 36 SRSRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVW 95
S R+YS SRSR R R R R++R
Sbjct: 186 SHRRSYSGSRSRSRSRRRSRSRSRRSSRS------------------------------- 214
Query: 96 NRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRS-PRS--SSSRSSSPYSKSP 152
SRS + RSRSRS RS RSRS+ R+S S+S P+S S S SK
Sbjct: 215 ---RSRSISKSRSRSRS---RSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDE 268
Query: 153 VSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSES 196
K R ++ K G+ +S +S+SQ PS++
Sbjct: 269 YEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKA 312
Score = 38.1 bits (87), Expect = 0.036
Identities = 37/149 (24%), Positives = 51/149 (34%), Gaps = 17/149 (11%)
Query: 632 SYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRLAGEERVF---KEENQKGDKKLRCDS 688
S ++ +R + R IS S R +R G R ++ K K + D
Sbjct: 196 SRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDR 255
Query: 689 ADLRHDIDRRRKERSKERGDSKG--------------SRESSGSRKQEKTPKDYKEYKSY 734
H R + E K R S+ SR S SR P + +S
Sbjct: 256 GSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSV 315
Query: 735 KDDSKHKREQDHSRSSSSSASPSSPSSRE 763
K + SRS S S S S SSR+
Sbjct: 316 SPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
Score = 37.4 bits (85), Expect = 0.061
Identities = 33/125 (26%), Positives = 52/125 (41%), Gaps = 5/125 (4%)
Query: 651 RRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRR-KERSKERGDS 709
R I+ P T H R R ++ + R S I + R + RS+ +G S
Sbjct: 177 RLIEDKPRT--SHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRS 234
Query: 710 KGSRESSGSRKQEKT-PKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESK 768
+ + SR + K+ PK + S+ S+ K E + SRS S S SP + K
Sbjct: 235 RSRSKGRKSRSKSKSKPKSDRGSHSHSR-SRSKDEYEKSRSRSRSRSPKENGKGDIKSKS 293
Query: 769 KEREE 773
+ R +
Sbjct: 294 RSRSQ 298
Score = 35.0 bits (79), Expect = 0.30
Identities = 36/134 (26%), Positives = 49/134 (36%), Gaps = 18/134 (13%)
Query: 700 KERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSP 759
K R+ R GSR S SR++ +S S R + S+S S S S S
Sbjct: 182 KPRTSHRRSYSGSRSRSRSRRRS---------RSRSRRSSRSRSRSISKSRSRSRSRSKG 232
Query: 760 SSREEKESKKEREEEFKTHHEMKEYSGFAGVSRPRGTFHDDRDDGVDYWAKRGRGRGTFQ 819
SR + +K R K+ + K G SR R D + R R R +
Sbjct: 233 RSRSRSKGRKSRS---KSKSKPKSDRGSHSHSRSRS------KDEYEKSRSRSRSRSPKE 283
Query: 820 RGRGRFNFKKSGSS 833
G+G K S
Sbjct: 284 NGKGDIKSKSRSRS 297
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 72.4 bits (176), Expect = 2e-12
Identities = 161/849 (18%), Positives = 296/849 (34%), Gaps = 153/849 (18%)
Query: 4 SNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRNNR 63
+NS S S + S+SRS S + + S + ++SRS D + ++++ ++
Sbjct: 157 NNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDH-----HSKEHQRSK 211
Query: 64 GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRS--PRRGRSRSRSPKR------ 115
R P + P + +HS P S+S S +
Sbjct: 212 SPRDP--------------DANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYV 257
Query: 116 RSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKAEGEPQ--- 172
R + Q S S S +S P SK+ ++K + + A G+
Sbjct: 258 RPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVD 317
Query: 173 ----------------EESPLKSKSQEEPKDTFE-------------HDPSESIDEFNKS 203
+P K++ + P T E ++PS++ +
Sbjct: 318 EILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSK 377
Query: 204 SATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSI 263
S D+ S + + P +TP S S H+++ + S
Sbjct: 378 SMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSH--------HNSEGADNSRDDSS 429
Query: 264 QHSPERSGSGSVGNGSSRYSPSQ-NSPIHHIPSRRSPAKT----------------IAPQ 306
HS S SGS S S S+ N P P T ++P
Sbjct: 430 SHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPA 489
Query: 307 NAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEK 366
++ + +G +Q T + +TD RD + +KGSE
Sbjct: 490 SSVDSNIPSSQGYKKEGREQGTGNS------YTDTSGPKETSSATPGRDSKTI-QKGSES 542
Query: 367 GRAEGEWEDQEALDYFSDKES-GKQKFNDSEGDDTEETEDYRQFRKSVLADQGKSFATAS 425
GR G + D + + + GK++ +E EE + D S ++
Sbjct: 543 GR--GRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSR 600
Query: 426 HRNTEEEGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVERPSTTKDKHKEEDKNSE- 484
H K + KG+R+ + +E K+ RP+ K K+K K+S+
Sbjct: 601 H------------KAATKGSRKPNIKKESKSSP---------RPTAEKKKYKSTSKSSQK 639
Query: 485 -RITVKKETQSPEQVKSEKLKDLFDYSP-PLHKNLDAREKSTFREESPLRIKMIASDSHR 542
R ++ +T S + +SE L P + S E+S R +M +
Sbjct: 640 SREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSP---- 695
Query: 543 PEVKLKMAPVPLDDSNRPASLTKDRLLASTLVHSVKKEQEFRSIFDHIKLPQASKSTSES 602
E K ++P+ D P + D L + + KE E P+ K
Sbjct: 696 MEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETE---------PPKGEKKNVPE 746
Query: 603 FIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDIS--PSTL 660
H +E +++ N+ ++ + ++ K P+ + PS+
Sbjct: 747 ---------KHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSN 797
Query: 661 RKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRK---ERSKERGDSKGSRESSG 717
R+ ++ + KE++ S D + + R++ + S + S ++E+SG
Sbjct: 798 RESSK----QSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSG 853
Query: 718 SRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSP---SSREEKESKKEREEE 774
S K + K+ + K S K ++ + SSSS+ PS+P SS+ + +
Sbjct: 854 SSKNSSSTSKQKKTEG-KTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRN 912
Query: 775 FKTHHEMKE 783
+ H ++E
Sbjct: 913 YSADHYLQE 921
Score = 60.8 bits (146), Expect = 5e-09
Identities = 178/859 (20%), Positives = 303/859 (35%), Gaps = 126/859 (14%)
Query: 38 SRTYSRSRSRDRMYSRDYRRDYRNNRGMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNR 97
S + S+ RS +R + G R Y G +G + ++
Sbjct: 116 STSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSK 175
Query: 98 RHSRSPRRGR-------SRSRSPKRRSVSSQRSRSRSRRSYRS-----SRSPRSSSSRSS 145
S SP + + S SRS S + RS+S R + SR P SS S+
Sbjct: 176 SRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHST 235
Query: 146 SPYSKSPVSKRRGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSA 205
+ S +SK +K T P+ + EPK + EH S+S + +S
Sbjct: 236 QSFPPSLMSKSNSMLQKPTAYVR-------PMDGQESMEPKLSSEHYSSQS----HGNSM 284
Query: 206 TSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPMLSTVHS------AKNTPSQH 259
T ++ P A+ + P P + S SC D + HS A +TP +
Sbjct: 285 T--ELKPSSKAHLTKLKIPSQP--LDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKT 340
Query: 260 SHSIQHSPER-SGSGSVGNGSS-RYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRS 317
S P + S + G G RY+PS+ S H S +D+ + S
Sbjct: 341 EPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSML------------KDDLKLSS 388
Query: 318 SFYPDGGDQETAKTGKFLKRFT----DEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEW 373
S DG +Q+ KT + R T E S N+RD ++S GSE
Sbjct: 389 SEDSDG-EQDCDKT---MPRSTPGSNSEPSHHNSEGADNSRD-DSSSHSGSESSSGS--- 440
Query: 374 EDQEALDYFSDKESGKQKFNDSEGDDTEETEDYR--QFRKSVLADQGKSFATASHRNTEE 431
D E+ SD E+ + + S + T ++ + V + ++
Sbjct: 441 -DSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSS 499
Query: 432 EGLKYKSKVSLKGNRESDGFREEKNYKLKETGYVVE-RPSTTKDKHKEEDKNSERITVKK 490
+G K + + GN +D KET R S T K E + ++
Sbjct: 500 QGYKKEGREQGTGNSYTDTSGP------KETSSATPGRDSKTIQKGSESGRGRQK----- 548
Query: 491 ETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVKLKMA 550
SP Q S ++ T ++ P + + A++ R +K++ +
Sbjct: 549 ---SPAQSDS------------------TTQRRTVGKKQPKKAEKAAAEEPRGGLKIE-S 586
Query: 551 PVPLDDSNRPASLTKDRLLASTLVHSVKKEQEF--RSIFDHIKLPQASKSTSES--FIQH 606
P+D ++ S + ++KKE + R + K SKS+ +S I+
Sbjct: 587 ETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIET 646
Query: 607 IVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTRQKSPEIHRRIDISPSTLRKHTRL 666
S + + ++ T ++ + + S+ ++ R+ SP
Sbjct: 647 DTSSSDSDESESLPPSSQT--PKYPESNRTPVKPSSVEEEDSFFRQRMFSPME------- 697
Query: 667 AGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPK 726
E+ + ++ D+ DL + R + KE KG +++ + + K
Sbjct: 698 --EKELLSPLSEPDDRYPLIVKIDLNL-LTRIPGKPYKETEPPKGEKKNVPEKHTREAQK 754
Query: 727 DYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSREEKESKKEREEEFKTHHEMKEYSG 786
E S K KHK E D+ S S +S K S + E
Sbjct: 755 QASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPS 814
Query: 787 FAG--VSRPRGTFHDDRDDGVDYWAKRGRGRGTFQRGRGRFNFKKSGSSPKWTHDKYQGD 844
AG S+ T H R KR + + + N + SGSS + Q
Sbjct: 815 PAGPVPSKDPKTEHGSR--------KRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQ-- 864
Query: 845 GIVEDEEETMENNEEKKDR 863
+ E +T +++E K++
Sbjct: 865 --KKTEGKTSSSSKEVKEK 881
Score = 52.4 bits (124), Expect = 2e-06
Identities = 123/569 (21%), Positives = 200/569 (35%), Gaps = 109/569 (19%)
Query: 2 GRSNSRSHSSRSKSRSQSSSRSRSRSHSRKKRYRSRSRTYSRSRSRDRMYSRDYRRDYRN 61
G NSR SS S S S+SSS S S S S + + S S + + ++ D
Sbjct: 420 GADNSRDDSS-SHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWL 478
Query: 62 NR--------------GMRRPYGYRGRGRGYYQGGGGRYHRGGYRPVWNRRHSRSPRRGR 107
N+ + GY+ GR QG G Y
Sbjct: 479 NKVNPHKVSPASSVDSNIPSSQGYKKEGRE--QGTGNSY--------------------- 515
Query: 108 SRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKKA 167
+ + PK S S + R S + S R SP ++RR +KQ KKA
Sbjct: 516 TDTSGPKETS-----SATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKA 570
Query: 168 EGEPQEE--SPLKSKSQEEPKDTFEHDPSESIDEFNKSSATSGDIWPGLSAYDNSPRSPH 225
E EE LK +S E P D PS +AT G P + S
Sbjct: 571 EKAAAEEPRGGLKIES-ETPVDLASSMPSS-----RHKAATKGSRKPNI-----KKESKS 619
Query: 226 SPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGSGSVGNGSSRYSPS 285
SP P A S+ S+ S + E S S + S PS
Sbjct: 620 SPRPTAEKKKYKST-----------------SKSSQKSREIIETDTSSSDSDESESLPPS 662
Query: 286 QNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTGKFLKRFTDEESRV 345
+P + S R+P K P + ++S R + ++E L ++ + R
Sbjct: 663 SQTP-KYPESNRTPVK---PSSVEEEDSFFRQRMFSPMEEKE------LLSPLSEPDDRY 712
Query: 346 FLLDRGNTR---------DKEASKEKGSEKGRAEGEWEDQEALDYFSDKES--GKQKFND 394
L+ + + KE KG +K E +EA S+K S GK+K +
Sbjct: 713 PLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEK--HTREAQKQASEKVSNKGKRKHKN 770
Query: 395 SEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKSKVSLKGNRESDGFREE 454
+ + E++ + K+ + S +S ++ +E S +++
Sbjct: 771 EDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGS 830
Query: 455 KNYKLKETGYVVERPSTTKDKHKEEDKNSERITVKKETQSPEQVKSEKLKDLFDYS---- 510
+ + ++ + ++ K+ KNS + +K+T+ S+++K+ S
Sbjct: 831 RKRTISQSSSLKSSSNSNKET-SGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNC 889
Query: 511 PPLHKNLDAREKSTFREESPLRIKMIASD 539
PP LD+ P R K++ D
Sbjct: 890 PPSAPTLDS--------SKPRRTKLVFDD 910
Score = 52.0 bits (123), Expect = 2e-06
Identities = 170/849 (20%), Positives = 293/849 (34%), Gaps = 150/849 (17%)
Query: 95 WNRRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSS-------- 146
+ +RH S + + P + SQ+ S + + S R+ SSS ++S
Sbjct: 95 FEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRE 154
Query: 147 PYSKSPVSKRRGSQ-----EKQTKKAEGEPQEESPLKSK----------SQEEPKDTFEH 191
Y+ S S R+ Q K + G+PQ S L S S+E +
Sbjct: 155 SYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPR 214
Query: 192 DPSESIDE-----FNKSSATSGDIWPGLSAYDNSPRSPHSPSPIATPPSQSSSCSDAPML 246
DP + D F+ ++ P L + NS P+ P S P L
Sbjct: 215 DPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNS--MLQKPTAYVRPMDGQESME--PKL 270
Query: 247 STVHSAKNT---------PSQHSH----SIQHSP-ERSGSGSVGNGSSRYSPSQNS---P 289
S+ H + + PS +H I P + S SG V +S P
Sbjct: 271 SSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPP 330
Query: 290 IH--HIPSRRSPAKTIAPQNAPRDESRGR---------------------------SSFY 320
+ H P + P+K P + + G SS
Sbjct: 331 LTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSE 390
Query: 321 PDGGDQETAKT-GKFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEAL 379
G+Q+ KT + E S N+RD ++S GSE D E+
Sbjct: 391 DSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRD-DSSSHSGSESSSG----SDSESE 445
Query: 380 DYFSDKESGKQKFNDSEGDDTEETEDYR--QFRKSVLADQGKSFATASHRNTEEEGLKYK 437
SD E+ + + S + T ++ + V + ++ +G K +
Sbjct: 446 SSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKE 505
Query: 438 SKVSLKGNRESD--GFREEKNYKLKETGYVVERPSTT----KDKHKEEDKNSERITV-KK 490
+ GN +D G +E + +++ S + + + D ++R TV KK
Sbjct: 506 GREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKK 565
Query: 491 ETQSPEQVKSEKLKDLFDYSPPLHKNLDAREKSTFREESPLRIKMIASDSHRPEVK--LK 548
+ + E+ +E+ + +L + S+ R K S +P +K K
Sbjct: 566 QPKKAEKAAAEEPRGGLKIESETPVDLASSMPSS-------RHKAATKGSRKPNIKKESK 618
Query: 549 MAPVPLDDSNRPASLTKDRLLASTLVH---SVKKEQEFRSIFDHIKLPQ----------- 594
+P P + + S +K + ++ S E S+ + P+
Sbjct: 619 SSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKP 678
Query: 595 ASKSTSESFIQHIVSLVHHVKEQYFKSAAMTLNERFTSYQKATEEHSTR---QKSPEIHR 651
+S +SF + + ++E+ S ++R+ K TR + E
Sbjct: 679 SSVEEEDSFFRQ--RMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEP 736
Query: 652 RIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKG 711
+ KHTR A ++ K N KG +K + + D R ++ K K K
Sbjct: 737 PKGEKKNVPEKHTREAQKQASEKVSN-KGKRKHK-NEDDNRASESKKPKTEDKNSAGHKP 794
Query: 712 SRESSGSRKQEKTPKDY----------KEYKSYKDDSKHKREQDHS-RSSSSSASPSSPS 760
S S++ KD K+ K+ K Q S +SSS+S +S S
Sbjct: 795 SSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGS 854
Query: 761 SREEKESKKEREEEFKTHHEMKEYSGFA--------------GVSRPRGT--FHDDRDDG 804
S+ + K+++ E KT KE A S+PR T DDR+
Sbjct: 855 SKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRNYS 914
Query: 805 VDYWAKRGR 813
D++ + +
Sbjct: 915 ADHYLQEAK 923
Score = 38.5 bits (88), Expect = 0.027
Identities = 73/346 (21%), Positives = 120/346 (34%), Gaps = 34/346 (9%)
Query: 97 RRHSRSPRRGRSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKR 156
++ S+S R + + K S SSQ+SR SS S S S SS K P S R
Sbjct: 614 KKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNR 673
Query: 157 RGSQEKQTKKAEGEPQEESPLKSKSQEEPKDTFEHDPSESIDEFNKSSATS--GDIWPGL 214
+P+K S EE F ++E S S D +P +
Sbjct: 674 ------------------TPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLI 715
Query: 215 SAYDNS--PRSPHSPSPIATPPSQSSSCSDAPMLSTVHSAKNTPSQHSHSIQHSPERSGS 272
D + R P P PP + P T + K + S+ + +
Sbjct: 716 VKIDLNLLTRIPGKPYKETEPPKGEK--KNVPEKHTREAQKQASEKVSNKGKRKHKNEDD 773
Query: 273 GSVGNGSSRYSPSQNSPIHHIPSRRSPAKTIAPQNAPRDESRGRSSFYPDGGDQETAKTG 332
+ +NS H S R +K Q+A +++ S P + G
Sbjct: 774 NRASESKKPKTEDKNSAGHKPSSNRESSK----QSAAKEKDLLPSPAGPVPSKDPKTEHG 829
Query: 333 KFLKRFTDEESRVFLLDRGNTRDKEASKEKGSEKGRAEGEWEDQEALDYFSDKESGKQKF 392
KR + S + N +SK S + + E + + S + K
Sbjct: 830 S-RKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSS----SKEVKEKAPS 884
Query: 393 NDSEGDDTEETEDYRQFRKSVLADQGKSFATASHRNTEEEGLKYKS 438
+ S + T D + R++ L +++ +A H E + LK+ +
Sbjct: 885 SSSNCPPSAPTLDSSKPRRTKLVFDDRNY-SADHYLQEAKKLKHNA 929
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.123 0.343
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,695,289
Number of Sequences: 37866
Number of extensions: 2057068
Number of successful extensions: 36750
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 453
Number of HSP's successfully gapped in prelim test: 1140
Number of HSP's that attempted gapping in prelim test: 14543
Number of HSP's gapped (non-prelim): 11600
length of query: 869
length of database: 18,247,518
effective HSP length: 111
effective length of query: 758
effective length of database: 14,044,392
effective search space: 10645649136
effective search space used: 10645649136
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.