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Search of human proteins with 117168273
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117168273 coiled-coil domain containing 33 isoform 1 [Homo
sapiens]
(755 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117168273 coiled-coil domain containing 33 isoform 1 [Homo sa... 1486 0.0
gi|117168269 coiled-coil domain containing 33 isoform 2 [Homo sa... 530 e-150
gi|221139761 zinc finger protein 853 [Homo sapiens] 54 7e-07
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 50 6e-06
gi|48762942 huntingtin interacting protein-1-related [Homo sapiens] 50 1e-05
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 50 1e-05
gi|239750456 PREDICTED: similar to KIAA0655 protein [Homo sapiens] 50 1e-05
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 50 1e-05
gi|32698688 citron [Homo sapiens] 49 1e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 49 2e-05
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 49 2e-05
gi|148746195 trichohyalin [Homo sapiens] 48 3e-05
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 48 4e-05
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 48 4e-05
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 47 5e-05
gi|31982906 cingulin-like 1 [Homo sapiens] 47 5e-05
gi|239745087 PREDICTED: similar to Golgin subfamily A member 8-l... 47 7e-05
gi|39930479 DIX domain containing 1 isoform b [Homo sapiens] 47 9e-05
gi|83816971 DIX domain containing 1 isoform a [Homo sapiens] 47 9e-05
gi|21687020 ecotropic viral integration site 5-like isoform 2 [H... 46 1e-04
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom... 46 1e-04
gi|109659849 filamin A interacting protein 1-like isoform 2 [Hom... 46 1e-04
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom... 46 1e-04
gi|153945715 myosin VC [Homo sapiens] 46 1e-04
gi|229577000 ecotropic viral integration site 5-like isoform 1 [... 46 1e-04
gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] 46 1e-04
gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] 46 1e-04
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 45 2e-04
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 45 2e-04
gi|55749678 ninein-like [Homo sapiens] 45 3e-04
>gi|117168273 coiled-coil domain containing 33 isoform 1 [Homo
sapiens]
Length = 755
Score = 1486 bits (3846), Expect = 0.0
Identities = 755/755 (100%), Positives = 755/755 (100%)
Query: 1 MGLKNKKNTEDPEEPLIASQSTEPEIGHLSPSKKETIMVTLHGATNLPACKDGSEPWPYV 60
MGLKNKKNTEDPEEPLIASQSTEPEIGHLSPSKKETIMVTLHGATNLPACKDGSEPWPYV
Sbjct: 1 MGLKNKKNTEDPEEPLIASQSTEPEIGHLSPSKKETIMVTLHGATNLPACKDGSEPWPYV 60
Query: 61 VVKSTSEEKNNQSSKAVTSVTSEPTRAPIWGDTVNVEIQAEDAGQEDVILKVVDNRKKQE 120
VVKSTSEEKNNQSSKAVTSVTSEPTRAPIWGDTVNVEIQAEDAGQEDVILKVVDNRKKQE
Sbjct: 61 VVKSTSEEKNNQSSKAVTSVTSEPTRAPIWGDTVNVEIQAEDAGQEDVILKVVDNRKKQE 120
Query: 121 LLSYKIPIKYLRVFHPYHFELVKPTESGKADEATAKTQLYATVVRKSSFIPRYIGCNHMA 180
LLSYKIPIKYLRVFHPYHFELVKPTESGKADEATAKTQLYATVVRKSSFIPRYIGCNHMA
Sbjct: 121 LLSYKIPIKYLRVFHPYHFELVKPTESGKADEATAKTQLYATVVRKSSFIPRYIGCNHMA 180
Query: 181 LEIFLRGVNEPLANNPNPIVVIARVVPNYKEFKVSQANRDLASVGLPITPLSFPIPSMMN 240
LEIFLRGVNEPLANNPNPIVVIARVVPNYKEFKVSQANRDLASVGLPITPLSFPIPSMMN
Sbjct: 181 LEIFLRGVNEPLANNPNPIVVIARVVPNYKEFKVSQANRDLASVGLPITPLSFPIPSMMN 240
Query: 241 FDVPRVSQNGCPQLSKPGGPPEQPLWNQSFLFQGRDGATSFSEDTALVLEYYSSTSMKGS 300
FDVPRVSQNGCPQLSKPGGPPEQPLWNQSFLFQGRDGATSFSEDTALVLEYYSSTSMKGS
Sbjct: 241 FDVPRVSQNGCPQLSKPGGPPEQPLWNQSFLFQGRDGATSFSEDTALVLEYYSSTSMKGS 300
Query: 301 QPWTLNQPLGISVLPLKSRLYQKMLTGKGLDGLHVERLPIMDTSLKTINDEAPTVALSFQ 360
QPWTLNQPLGISVLPLKSRLYQKMLTGKGLDGLHVERLPIMDTSLKTINDEAPTVALSFQ
Sbjct: 301 QPWTLNQPLGISVLPLKSRLYQKMLTGKGLDGLHVERLPIMDTSLKTINDEAPTVALSFQ 360
Query: 361 LLSSERPENFLTPNNSKALPTLDPKILDKKLRTIQESWSKDTVSSTMDLSTSTPREAEEE 420
LLSSERPENFLTPNNSKALPTLDPKILDKKLRTIQESWSKDTVSSTMDLSTSTPREAEEE
Sbjct: 361 LLSSERPENFLTPNNSKALPTLDPKILDKKLRTIQESWSKDTVSSTMDLSTSTPREAEEE 420
Query: 421 PLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKAS 480
PLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKAS
Sbjct: 421 PLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKAS 480
Query: 481 EAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQY 540
EAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQY
Sbjct: 481 EAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQY 540
Query: 541 QGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGL 600
QGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGL
Sbjct: 541 QGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGL 600
Query: 601 PLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDKFNLLA 660
PLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDKFNLLA
Sbjct: 601 PLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDKFNLLA 660
Query: 661 KLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPSALTHSM 720
KLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPSALTHSM
Sbjct: 661 KLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPSALTHSM 720
Query: 721 DLKQPSELEPLLPSSDSKLNKPLSPQKETANSQQT 755
DLKQPSELEPLLPSSDSKLNKPLSPQKETANSQQT
Sbjct: 721 DLKQPSELEPLLPSSDSKLNKPLSPQKETANSQQT 755
>gi|117168269 coiled-coil domain containing 33 isoform 2 [Homo
sapiens]
Length = 367
Score = 530 bits (1364), Expect = e-150
Identities = 283/318 (88%), Positives = 284/318 (89%), Gaps = 34/318 (10%)
Query: 430 TEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMK 489
+EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMK
Sbjct: 23 SEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMK 82
Query: 490 QKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKA 549
QKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKA
Sbjct: 83 QKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKA 142
Query: 550 LEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENL 609
LEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENL
Sbjct: 143 LEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENL 202
Query: 610 PVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALP----------------------- 646
PVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALP
Sbjct: 203 PVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPVDPGELGAGGDLTERLQETHGPG 262
Query: 647 -----------DLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQ 695
DLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQ
Sbjct: 263 HSECTETLPAQDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQ 322
Query: 696 EQEKGFRHPSNSIIIEQP 713
EQEKGFRHPSNSIIIEQP
Sbjct: 323 EQEKGFRHPSNSIIIEQP 340
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 53.5 bits (127), Expect = 7e-07
Identities = 64/311 (20%), Positives = 136/311 (43%), Gaps = 34/311 (10%)
Query: 394 IQESWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQA 453
+Q+ +D L + + L PE+ M+ ++ + ++ L++Q
Sbjct: 118 LQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQL---MHQQQQLQPQQVQEQQRLQQQQ 174
Query: 454 SILEGENRILRSRLAQQEEEEGQGKASEA--QNTVSMKQKLLLSE---LDMKKLRDRVQH 508
L+ + + L QQE+ + Q + + Q ++Q+ LL + L ++ + + +
Sbjct: 175 EQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQ 234
Query: 509 LQNE----LIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKM 564
LQ + L+++ + ++ LL Q Q Q LL+Q Q +LQ+ L++ + Q++ +++
Sbjct: 235 LQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQL 294
Query: 565 ERVLEDRLQDRS-KPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAK 623
+ +++LQ + +PPPL ++ E + +EL V L +
Sbjct: 295 LQQQQEQLQQQQLQPPPLEPEE--------------------EEEVELELMPVDLGSEQE 334
Query: 624 LRTELDKNRHQQAPIILQQQALPDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRW 683
L + + QQ + QQ+ L + L +LE Q ++ E QLE +
Sbjct: 335 LEQQRQELERQQ-ELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVEL 393
Query: 684 GREKQDLATRL 694
G ++Q++ L
Sbjct: 394 GAQQQEVQLEL 404
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 50.4 bits (119), Expect = 6e-06
Identities = 73/341 (21%), Positives = 141/341 (41%), Gaps = 49/341 (14%)
Query: 363 SSERPENFLTPNNSKALPTLDPKILDKKL---RTIQESWSKDTVSSTMDLSTSTPREAEE 419
++E E + K+ L+ K L +KL + + +T+ M RE E+
Sbjct: 189 NAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEK 248
Query: 420 EPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKA 479
+ E + R KM E +RRQ L + + LR +QE+E + K
Sbjct: 249 KIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELR----EQEKELREQKK 304
Query: 480 SEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQ 539
Q +Q+ + E + +K+R++ + + + R ++EK++ Q + Q + +
Sbjct: 305 LREQEEQMQEQEEKMWEQE-EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE 363
Query: 540 YQGKLQKMKALEETVRHQEKVIEKMERVLED-RLQDRSKPPPLNRQQGKPYTGFPMLSAS 598
+L++ EE +R QEK+ E+ E++ E+ R+++R K
Sbjct: 364 QDERLREK---EERMREQEKMWEQEEKMQEEERIREREK--------------------- 399
Query: 599 GLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDKFNL 658
M E + E + + ++N +Q QQQ LP+ +K
Sbjct: 400 -----KMREE------EETMREQEEKMQKQEENMWEQEEKEWQQQRLPE----QKEKLWE 444
Query: 659 LAKLEHAQSRILSLESQLEDSARRWGREKQD-LATRLQEQE 698
K++ + +I E ++ D WG+EK+ +++EQE
Sbjct: 445 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 485
Score = 47.8 bits (112), Expect = 4e-05
Identities = 53/282 (18%), Positives = 116/282 (41%), Gaps = 44/282 (15%)
Query: 466 RLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLL 525
RLA+ E+ E Q E + + + K LL ++ L++ + + EL ++EK++
Sbjct: 197 RLAESEKSEIQLNVKELKRKLE-RAKFLLPQVQTNTLQEEMWRQEEEL---REQEKKIRK 252
Query: 526 LYQAQQPQAALLKQYQGKL----QKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPL 581
+ Q L++ +GK+ +KM+ E+ +R QEK + + E+ L ++ + R + +
Sbjct: 253 QEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQM 312
Query: 582 NRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQ 641
Q+ K + + K+R + +K Q+ + Q
Sbjct: 313 QEQEEK-----------------------------MWEQEEKMREQEEKMWRQEERLWEQ 343
Query: 642 QQALPDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGR-EKQDLATRLQEQEKG 700
++ + + D+ ++ R+ E ++ + + W + EK R++E+EK
Sbjct: 344 EKQMREQEQKMRDQEE---RMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKK 400
Query: 701 FRHPSNSIIIEQPSALTHSMDLKQPSELE---PLLPSSDSKL 739
R ++ ++ ++ + E E LP KL
Sbjct: 401 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 442
Score = 35.4 bits (80), Expect = 0.20
Identities = 34/183 (18%), Positives = 81/183 (44%), Gaps = 9/183 (4%)
Query: 415 REAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASIL-EGENRILRSRLAQQEEE 473
RE EE E + R +KM E ++ Q + E E ++ + +E
Sbjct: 570 REEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQE 629
Query: 474 EGQGKASEAQNTVSMKQKLLLSELDMK----KLRDRVQHLQNELIRKNDREKELLLLYQA 529
+ + + + ++K+ E M+ K+R++ + +Q + + ++E+++ +
Sbjct: 630 QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEK 689
Query: 530 QQPQAALLKQYQGKL----QKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQ 585
+ Q ++ + K+ +KM EE + QE++ EK ER+ + + + + + P +
Sbjct: 690 MREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERC 749
Query: 586 GKP 588
+P
Sbjct: 750 SEP 752
Score = 34.7 bits (78), Expect = 0.34
Identities = 54/321 (16%), Positives = 132/321 (41%), Gaps = 31/321 (9%)
Query: 388 DKKLRTIQESWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAMQKMAEDIL 447
++K+R +E W ++ + RE E++ E + ++M E
Sbjct: 459 EEKIRDQEEMWGQEKKMWRQEKM----REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDE 514
Query: 448 SLRRQASILEGENRIL-RSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRV 506
LR E E R+ + ++ QQEE+ + K ++ Q + Q+ + E + + R++
Sbjct: 515 RLR------EKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKK 568
Query: 507 QHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMER 566
+ E++R+ + + Q Q +++ + K+ + + E+ +EK+ E+ E+
Sbjct: 569 MREEEEMMREQEEK---------MQEQEEKMREQEEKMWEQE--EKMQEQEEKMWEQEEK 617
Query: 567 VLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRT 626
+ E +D+ + Q+ + + + E + E + + K++
Sbjct: 618 MWEQEEEDK-----MQEQEEMMWEQEEKMQEQEEKMWEQEEKMR-EQEEKMREQEEKMQG 671
Query: 627 ELDKNRHQQAPIILQQQAL---PDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRW 683
+ +K R Q+ + Q++ + + + G +K + Q + + ++ + R
Sbjct: 672 QEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERI 731
Query: 684 GREKQDLATRLQEQEKGFRHP 704
+K+ + RL E E+ P
Sbjct: 732 RDQKEKMQERLPEHEERCSEP 752
Score = 32.3 bits (72), Expect = 1.7
Identities = 37/199 (18%), Positives = 82/199 (41%), Gaps = 15/199 (7%)
Query: 388 DKKLRTIQESWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAMQKMAEDIL 447
+KK+R +E + M RE EE+ + +M M + E +
Sbjct: 566 EKKMREEEEMMREQ--EEKMQEQEEKMREQEEKM----WEQEEKMQEQEEKMWEQEEKMW 619
Query: 448 SLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMK----KLR 503
+ + E E + QE+EE + E ++K+ E M+ K+R
Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR--EQEEKMREQEEKMQGQEEKMR 677
Query: 504 DRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKL---QKMKALEETVRHQEKV 560
++ + +Q + + ++E+++ + Q + + K+ ++M+ EE +R Q++
Sbjct: 678 EQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEK 737
Query: 561 IEKMERVLEDRLQDRSKPP 579
+++ E+R + PP
Sbjct: 738 MQERLPEHEERCSEPCLPP 756
>gi|48762942 huntingtin interacting protein-1-related [Homo sapiens]
Length = 1068
Score = 49.7 bits (117), Expect = 1e-05
Identities = 79/316 (25%), Positives = 128/316 (40%), Gaps = 66/316 (20%)
Query: 431 EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQ 490
E+ R+ QK D LR + + L R AQ E E QG EA+ S +
Sbjct: 394 ELEEQRKQKQKALVDNEQLRHELAQL---------RAAQLEGERSQGLREEAERKASATE 444
Query: 491 KLLLSELDMKKLRDRVQHLQNELIRKN-DREKELLLLYQAQQPQAALLKQYQGKLQKMKA 549
+K+ + H+ EL+RKN D K+L + Q+Q+ A + +Q +++++K
Sbjct: 445 ARYNK---LKEKHSELVHVHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQVEQVKR 501
Query: 550 LEETVRHQEK--VIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGE 607
E ++ +EK +EK++R LE +K L R Q
Sbjct: 502 -ESELKLEEKSDQLEKLKRELE------AKAGELARAQ---------------------- 532
Query: 608 NLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDKFNLLAKLEHAQS 667
E S ++L + LD A D LSG + A L AQS
Sbjct: 533 ----EALSHTEQSKSELSSRLD-----------TLSAEKDALSGAVRQRE--ADLLAAQS 575
Query: 668 RILSLESQLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPSALTHSMDLKQPSE 727
+ E+ L +R +E+ +L RL E+E + ++ EQ + L + +E
Sbjct: 576 LVRETEAALSREQQRSSQEQGELQGRLAERESQEQGLRQRLLDEQFAVLRGA-----AAE 630
Query: 728 LEPLLPSSDSKLNKPL 743
+L + SKL+ PL
Sbjct: 631 AAGILQDAVSKLDDPL 646
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 49.7 bits (117), Expect = 1e-05
Identities = 64/343 (18%), Positives = 151/343 (44%), Gaps = 41/343 (11%)
Query: 381 TLDPKILDKKLRTIQESWS-KDTVSSTMDLSTSTPREAEEEP--LVPEMSHDTEMNNYRR 437
T+ + L KK +QE ++ S + L+ + E L+P++ +T R
Sbjct: 217 TITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWR 276
Query: 438 AMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEE-----GQGKASEAQNTVSMKQKL 492
+++ E +R+Q + + LR + + E+E + + E + + ++K
Sbjct: 277 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKE 336
Query: 493 LLSELDMKKLRDRVQHLQNELIRKND--REKELLLLYQAQQ--PQAALLKQYQGKL---- 544
L + ++++ +++Q + ++ + + RE+E + Q ++ Q +++ + K+
Sbjct: 337 LREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 396
Query: 545 -------QKMKALEETVRHQEKVIEKMERVLED-RLQDRSKPPPLNRQQGKPYTGFPMLS 596
++++ EE +R QEK+ E++E++ E+ ++Q++ K R Q + +
Sbjct: 397 ERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKK---TRDQEEKMQEEERIR 453
Query: 597 ASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDKF 656
+ E + E + + ++N +Q QQQ LP+ +K
Sbjct: 454 EREKKMREEEET---------MREQEEKMQKQEENMWEQEEKEWQQQRLPE----QKEKL 500
Query: 657 NLLAKLEHAQSRILSLESQLEDSARRWGREKQD-LATRLQEQE 698
K++ + +I E ++ D WG+EK+ +++EQE
Sbjct: 501 WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 543
Score = 48.9 bits (115), Expect = 2e-05
Identities = 61/299 (20%), Positives = 126/299 (42%), Gaps = 25/299 (8%)
Query: 415 REAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEE 474
R+ EE+ E + R +KM LR Q L + + LR + +E+EE
Sbjct: 289 RKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEE 348
Query: 475 GQGKASE----------AQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELL 524
+ E Q +Q+ L E + K++R++ Q ++++ R ++++ L
Sbjct: 349 QMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE-KQMREQEQKMRDQEERMWEQDERLR 407
Query: 525 LLYQAQQPQAALLKQYQ--GKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLN 582
+ + Q + +Q + + +KM+ E+ R QE+ +++ ER+ E + R + +
Sbjct: 408 EKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMR 467
Query: 583 RQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQ 642
Q+ K +M E E L E + E +K + Q+ I Q+
Sbjct: 468 EQEEKMQK----------QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE 517
Query: 643 QALPDL--LSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQEK 699
+ + D + G K K+ + ++ E ++ D ++ +++ + + QEQEK
Sbjct: 518 EKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEK 576
Score = 46.2 bits (108), Expect = 1e-04
Identities = 60/308 (19%), Positives = 127/308 (41%), Gaps = 27/308 (8%)
Query: 445 DILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQ-NTVSMKQKL-----LLSELD 498
D LSL + + E ++ Q++ + + SE Q N +K+KL LL ++
Sbjct: 207 DALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQ 266
Query: 499 MKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKL----QKMKALEETV 554
L++ + + EL ++EK++ + Q L++ +GK+ +KM E+ +
Sbjct: 267 TNTLQEEMWRQEEEL---REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRL 323
Query: 555 RHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELY 614
R QEK + + E+ L ++ + R + + Q+ K + + + E
Sbjct: 324 REQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER------ 377
Query: 615 SVLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDKFNLLAKLEHAQSRILSLES 674
L + ++R + K R Q+ + Q + L + ++ + ++E + +
Sbjct: 378 --LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMRE---EKKM 432
Query: 675 QLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPSALTHSMDLKQPSELE---PL 731
Q ++ R EK R++E+EK R ++ ++ ++ + E E
Sbjct: 433 QEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 492
Query: 732 LPSSDSKL 739
LP KL
Sbjct: 493 LPEQKEKL 500
Score = 35.0 bits (79), Expect = 0.26
Identities = 52/287 (18%), Positives = 114/287 (39%), Gaps = 9/287 (3%)
Query: 415 REAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEE 474
R E+E + E E R +KM E R Q ++ E RI +EEEE
Sbjct: 405 RLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEE 464
Query: 475 GQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQA 534
+ E KQ+ + E + K+ + + Q E + + ++ +E Q+ +
Sbjct: 465 TMREQEEKM----QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 520
Query: 535 ALLKQYQGKLQKMKALEETVRHQEKVIEKMERV--LEDRLQDRSKPPPLNRQQGKPYTGF 592
++ G+ +KM E+ ++++ E+ E++ E ++ D+ + Q+ + T
Sbjct: 521 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD 580
Query: 593 PMLSASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGT 652
E E ++ + K++ + +K + Q+ + Q++ + +
Sbjct: 581 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQE---QE 637
Query: 653 SDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQEK 699
+ K+ + ++ + E + W EK ++QEQE+
Sbjct: 638 EKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEE 684
Score = 33.9 bits (76), Expect = 0.57
Identities = 26/132 (19%), Positives = 62/132 (46%), Gaps = 3/132 (2%)
Query: 431 EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEG---QGKASEAQNTVS 487
+M + +K D +R + S+ E E ++ +E+EE Q + + Q
Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEM 750
Query: 488 MKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKM 547
+Q+ + E + K + Q E + ++++ +E +++ ++ ++ +G+ +KM
Sbjct: 751 WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKM 810
Query: 548 KALEETVRHQEK 559
+ EE +R QE+
Sbjct: 811 RGQEEKMRGQEE 822
Score = 33.5 bits (75), Expect = 0.75
Identities = 35/202 (17%), Positives = 93/202 (46%), Gaps = 21/202 (10%)
Query: 395 QESWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQAS 454
+++W ++ + + + EEE ++ E + +M MQ+ E++ ++
Sbjct: 701 KKTWDQEKMREEESMREREKKMREEEEMMREQ--EEKMQEQEEKMQEQEEEMWE--QEEK 756
Query: 455 ILEGENRIL-RSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNEL 513
+ E E ++ + RL +Q+E+ + + + Q + +++ + + + + ++ Q E
Sbjct: 757 MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEK 816
Query: 514 IRKNDRE----------KELLLLYQAQQ---PQAALLKQYQGKLQKMKALEETVRHQEKV 560
+R + + +E + Q ++ + + ++ QG+ +KM+ EE +R QE+
Sbjct: 817 MRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEK 876
Query: 561 IEKME---RVLEDRLQDRSKPP 579
+ + E R E+++ PP
Sbjct: 877 MREQEEKMRGQEEKIYCVGSPP 898
>gi|239750456 PREDICTED: similar to KIAA0655 protein [Homo sapiens]
Length = 1048
Score = 49.7 bits (117), Expect = 1e-05
Identities = 79/316 (25%), Positives = 128/316 (40%), Gaps = 66/316 (20%)
Query: 431 EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQ 490
E+ R+ QK D LR + + L R AQ E E QG EA+ S +
Sbjct: 374 ELEEQRKQKQKALVDNEQLRHELAQL---------RAAQLEGERSQGLREEAERKASATE 424
Query: 491 KLLLSELDMKKLRDRVQHLQNELIRKN-DREKELLLLYQAQQPQAALLKQYQGKLQKMKA 549
+K+ + H+ EL+RKN D K+L + Q+Q+ A + +Q +++++K
Sbjct: 425 ARYNK---LKEKHSELVHVHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQVEQVKR 481
Query: 550 LEETVRHQEK--VIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGE 607
E ++ +EK +EK++R LE +K L R Q
Sbjct: 482 -ESELKLEEKSDQLEKLKRELE------AKAGELARAQ---------------------- 512
Query: 608 NLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDKFNLLAKLEHAQS 667
E S ++L + LD A D LSG + A L AQS
Sbjct: 513 ----EALSHTEQSKSELSSRLD-----------TLSAEKDALSGAVRQRE--ADLLAAQS 555
Query: 668 RILSLESQLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPSALTHSMDLKQPSE 727
+ E+ L +R +E+ +L RL E+E + ++ EQ + L + +E
Sbjct: 556 LVRETEAALSREQQRSSQEQGELQGRLAERESQEQGLRQRLLDEQFAVLRGA-----AAE 610
Query: 728 LEPLLPSSDSKLNKPL 743
+L + SKL+ PL
Sbjct: 611 AAGILQDAVSKLDDPL 626
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 49.7 bits (117), Expect = 1e-05
Identities = 111/503 (22%), Positives = 201/503 (39%), Gaps = 81/503 (16%)
Query: 305 LNQPLGISVLPLKSRLYQKMLTGKGLDGLHVERLPIMDTSLKTINDEAPTVALSFQLLSS 364
LNQ + I K L ++ K L+ + + ++ LK + + SF L
Sbjct: 2540 LNQVITIKDSQQKQLLEVQLQQNKELENKYAK----LEEKLKESEEANEDLRRSFNALQE 2595
Query: 365 ERPENFLTPNNSKALPTLDPKI--LDKKLRTIQESWSKDTVSSTMDL------------S 410
E+ + SK + +L I L +++ +QE + + + + S
Sbjct: 2596 EKQDL------SKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFS 2649
Query: 411 TSTPREAE-EEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQ 469
+S R AE EE LV + A +K+ E L+++ L + I+R+
Sbjct: 2650 SSQKRIAELEEELVCVQ---------KEAAKKVGEIEDKLKKELKHLHHDAGIMRNETET 2700
Query: 470 QEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQ-------HLQNELIRKNDREKE 522
EE A A++ V M+QKLL+ + K L ++Q LQN N+ E
Sbjct: 2701 AEERV----AELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDE 2756
Query: 523 LLLLYQAQQPQAALLKQYQGKLQKMK--ALEETV----RHQEKVIEKMERVLEDRLQDRS 576
L Y A + A LK+ QG L + + L ET +E + +E++ + L
Sbjct: 2757 LKRKYDASLKELAQLKE-QGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDE 2815
Query: 577 KPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQA 636
+ L+ Q Y S + L + ++L EL +E K R+ Q +
Sbjct: 2816 QLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAA-----QPS 2870
Query: 637 PIILQQQALPDLLSG-TSDKFNLLAKLEHAQSRILSLESQLED--SARRWGREKQD---- 689
+ Q+L +S +D+ LL +L++ Q + L + ++ + + +E QD
Sbjct: 2871 TSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKA 2930
Query: 690 ---LATRLQEQEKGFRHPSNSIIIEQPSALTHSMDLK------------QPSELEPLLPS 734
+ L+++ ++H + + +E+ S H +K Q S L+ L+
Sbjct: 2931 FQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQLSHLQNLIRE 2990
Query: 735 --SDSKLNKPLSPQKETANSQQT 755
S S +PL Q + S +T
Sbjct: 2991 LRSSSSQTQPLKVQYQRQASPET 3013
Score = 48.5 bits (114), Expect = 2e-05
Identities = 66/314 (21%), Positives = 127/314 (40%), Gaps = 38/314 (12%)
Query: 388 DKKLRTIQESWSK-----DTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAMQKM 442
D +L+ +QE +K + + T AEEE E ++ ++
Sbjct: 1881 DGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNY 1940
Query: 443 AEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKL 502
+D+ + + +LE E + L+ +++ EEE+ Q +K+K + K+
Sbjct: 1941 CQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQ----------LVKEKTKVESEIRKEY 1990
Query: 503 RDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIE 562
+++Q Q E K+ ++ LL + QQ L K +K+ ALE TV+ E V
Sbjct: 1991 LEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQT 2050
Query: 563 KMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENA 622
+ ++ LE ++ ++ ++ F +L ++ E V LA+N
Sbjct: 2051 ESQKDLEITKENLAQAVEHRKKAQAELASFKVLL----------DDTQSEAARV-LADNL 2099
Query: 623 KLRTELDKNRHQQAPIILQQQALPDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARR 682
KL+ EL N+ + Q+ +L +LE A+ + L + +++
Sbjct: 2100 KLKKELQSNKESVKSQMKQKDE------------DLERRLEQAEEKHLKEKKNMQEKLDA 2147
Query: 683 WGREKQDLATRLQE 696
REK L + E
Sbjct: 2148 LRREKVHLEETIGE 2161
Score = 41.2 bits (95), Expect = 0.004
Identities = 86/382 (22%), Positives = 155/382 (40%), Gaps = 66/382 (17%)
Query: 382 LDPKILDKKLRTIQESWSKDTVSSTMDLSTSTPREAEEEPLVPEM--------SHDTEMN 433
L + D + + ++ KDTV + L + E + L+ EM S +
Sbjct: 1516 LTKSLADVESQVSAQNKEKDTVLGRLALL-----QEERDKLITEMDRSLLENQSLSSSCE 1570
Query: 434 NYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLL 493
+ + A++ + ED L ++ L+ S++A E E Q K E Q + LL
Sbjct: 1571 SLKLALEGLTEDKEKLVKEIESLKS------SKIA--ESTEWQEKHKELQKEYEI---LL 1619
Query: 494 LSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEET 553
S ++ +R+QH+ E +R+ +E LY + A K+ + K L+E
Sbjct: 1620 QSYENVSNEAERIQHVV-EAVRQEKQE-----LYGKLRSTEANKKETE------KQLQEA 1667
Query: 554 VRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVEL 613
+ E++ EKM + + + Q K L + + L A P G + E
Sbjct: 1668 EQEMEEMKEKMRKFAKSKQQ---KILELEEENDR-------LRAEVHPAGDTAK----EC 1713
Query: 614 YSVLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDKFNLLAKLEHAQSRILSLE 673
LL+ NA ++ EL++ + + + + Q+L S+K +L +++ + +I E
Sbjct: 1714 METLLSSNASMKEELERVKMEYETLSKKFQSL------MSEKDSLSEEVQDLKHQI---E 1764
Query: 674 SQLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPSALTHSMDLKQP-SELEPLL 732
+ A EK D T + E+ + SI E + SM + SE P
Sbjct: 1765 GNVSKQANLEATEKHDNQTNVTEE------GTQSIPGETEEQDSLSMSTRPTCSESVPSA 1818
Query: 733 PSSDSKLNKPLSPQKETANSQQ 754
S++ ++K S E N Q
Sbjct: 1819 KSANPAVSKDFSSHDEINNYLQ 1840
Score = 40.8 bits (94), Expect = 0.005
Identities = 94/438 (21%), Positives = 167/438 (38%), Gaps = 121/438 (27%)
Query: 416 EAEEEPLVPEMSHDTEMNNYRRAMQKMAED-----------ILSLRRQASILEGENRILR 464
E E LV + +TEM R +Q+ E+ + L+++ + E N+IL
Sbjct: 234 EDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILS 293
Query: 465 SRLAQQEEEEGQGKASEAQNTVSMKQ---KLLLS--ELDMKKLRDRVQHLQNELIRKNDR 519
+L Q E E + +NTV ++ K+LL EL++ + + +LQ E+
Sbjct: 294 QQLQQMEAEH-----NTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEM------ 342
Query: 520 EKELLLLYQAQQPQAALLKQYQGKLQKMKA-LEETVRH---------------------- 556
L QA Q QA L +Y QK KA +EE H
Sbjct: 343 HHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQN 402
Query: 557 -------QEKVIEKMERV--LEDRLQDRSKP-------PPLNRQQGKPYTGFPMLSASGL 600
E+ ++ + + LED+LQ +SK PL + + T FP + G
Sbjct: 403 SKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGT 462
Query: 601 P------LGSMGENLPVEL-------------YSVLLAENAKLRTELD----KNRHQQAP 637
+ S+ + + VEL L AEN KL +++ +NR +A
Sbjct: 463 QAVTEENIASLQKRV-VELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEAD 521
Query: 638 IILQQQALPDLLSGTSDKFN--------------------LLAKLEHAQSRILSLESQLE 677
+ + ++ D+ + S LL +++ AQ I L+ QL+
Sbjct: 522 REVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQ 581
Query: 678 DSARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPSALTHSMDLKQPSELEPLLPSSDS 737
G+ ++ + +Q++ + I + + + L+ + PL+P+ +S
Sbjct: 582 ------GKRAEEADHEVLDQKEMKQMEGEGI-----APIKMKVFLEDTGQDFPLMPNEES 630
Query: 738 KLNKPLSPQKETANSQQT 755
L Q T + +T
Sbjct: 631 SLPAVEKEQASTEHQSRT 648
Score = 40.0 bits (92), Expect = 0.008
Identities = 67/298 (22%), Positives = 124/298 (41%), Gaps = 34/298 (11%)
Query: 429 DTEMNNYRRAMQKMAEDILSLRRQASILEG-----ENRILRSRLAQQEEEE----GQGKA 479
++E+ + + + ++ + + Q LEG E I S+ + ++ E +
Sbjct: 2311 ESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELT 2370
Query: 480 SEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDRE-KELL-LLYQAQQPQAALL 537
S ++MK++ ++S L K+ + +Q EL +++D+E KEL LL Q ++ L
Sbjct: 2371 SRLHEEINMKEQKIISLLSGKE--EAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLE 2428
Query: 538 KQYQGKLQKMKALEETVR-------HQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYT 590
++ + + K L ET++ Q+ ++ + + DR + +Q + +
Sbjct: 2429 EENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHL 2488
Query: 591 GFPMLSASGLPLGSMGEN--LPVELYSV------LLAENAKLRTELDKNRHQQAPIIL-- 640
+L L + EN L E+ + L +ENAKL EL + R +I
Sbjct: 2489 SI-ILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIK 2547
Query: 641 ---QQQALPDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQ 695
Q+Q L L + N AKLE L S EKQDL+ ++
Sbjct: 2548 DSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIE 2605
Score = 38.1 bits (87), Expect = 0.030
Identities = 88/438 (20%), Positives = 169/438 (38%), Gaps = 63/438 (14%)
Query: 361 LLSSERPENF-LTPNNSKA----------LPTLDPKILDKKLRTIQESWSKDTVSSTMDL 409
LLS E EN L N KA L T+ + + +K + S ++ + D
Sbjct: 2416 LLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDR 2475
Query: 410 STSTPREAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQ 469
++ EE L + D + K+ E+I LR L EN L + L Q
Sbjct: 2476 IVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQ 2535
Query: 470 QEEEEGQGKASEAQNTVSMKQKLLLSELDM---KKLRDRVQHLQNELIRKNDREKELLLL 526
E+ Q T+ Q+ L E+ + K+L ++ L+ +L + ++L
Sbjct: 2536 YREDLNQ------VITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRS 2589
Query: 527 YQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQG 586
+ A Q + L + +++ +K + Q +++ + Q + K ++R
Sbjct: 2590 FNALQEEKQDLSK---EIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSA 2646
Query: 587 KPYTGFPMLSASGLPLGSMGENL---PVELYSVLLAENAKLRTELDKNRHQQAPIILQQQ 643
+ S+S + + E L E + KL+ EL K+ H A I+ +
Sbjct: 2647 -------LFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKEL-KHLHHDAGIMRNET 2698
Query: 644 ALPD----------------LLSGTSDKFNLLAKLEHAQSRILSLES-------QLEDSA 680
+ LL T + L A+++ + SL++ +L++
Sbjct: 2699 ETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELK 2758
Query: 681 RRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPSALTHSMDLKQPSELEPL---LPSSDS 737
R++ ++LA Q +E+G + ++ + + +S + S LE L L S D
Sbjct: 2759 RKYDASLKELA---QLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDE 2815
Query: 738 KLNKPLSPQKETANSQQT 755
+L S +++ N Q+
Sbjct: 2816 QLLHLSSQLEDSYNQVQS 2833
Score = 37.7 bits (86), Expect = 0.040
Identities = 75/368 (20%), Positives = 149/368 (40%), Gaps = 44/368 (11%)
Query: 416 EAEEEPLVPEMSHDT--------EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRL 467
EAE+ L ++S T E+ + + K +I SL+ + E L+ +L
Sbjct: 1315 EAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKL 1374
Query: 468 AQQEEE--------EGQGKASEAQNTVSMKQK---LLLSELDMKKLRDRVQHLQNELIRK 516
+ + E Q K E Q +S K++ L +L K+ + +Q E+I +
Sbjct: 1375 ESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAA--LTKIQTEIIEQ 1432
Query: 517 NDREKELLLLYQAQQPQA-ALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRL--- 572
D K L + Q + +KQ Q +L +MK E + + + ++++R L+ L
Sbjct: 1433 EDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISR 1492
Query: 573 -----QDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVEL--YSVLLAENAKLR 625
+++S L+ +G L+ + + + L ++L E KL
Sbjct: 1493 KEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLI 1552
Query: 626 TELDKNRHQQAPIILQQQALPDLLSG-TSDKFNLLAKLEHAQSRILSLESQLEDSARRWG 684
TE+D++ + + ++L L G T DK L+ ++E +S ++ ++ ++ +
Sbjct: 1553 TEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQ 1612
Query: 685 REKQDL----------ATRLQEQEKGFRHPSNSIIIEQPSALTHSMDL-KQPSELEPLLP 733
+E + L A R+Q + R + + S + + KQ E E +
Sbjct: 1613 KEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEME 1672
Query: 734 SSDSKLNK 741
K+ K
Sbjct: 1673 EMKEKMRK 1680
Score = 30.4 bits (67), Expect = 6.3
Identities = 53/265 (20%), Positives = 103/265 (38%), Gaps = 24/265 (9%)
Query: 320 LYQKMLTGKGLDGLHVERLPIMDTSLKTINDEAPTVALSFQLLSSERP------ENFLTP 373
L +++ +G + L +++ + N E TV LL ER + L
Sbjct: 1502 LQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLE 1561
Query: 374 NNSKALPTLDPKILDKKLRTIQESWSKDTVS-STMDLSTSTPREAEEEPLVPE-----MS 427
N S + K+ + L +E K+ S + ++ ST + + + L E S
Sbjct: 1562 NQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQS 1621
Query: 428 HDTEMNNYRR---AMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQN 484
++ N R ++ + ++ L + E + +L + E+E + K +
Sbjct: 1622 YENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKF 1681
Query: 485 TVSMKQKLLLSELDMKKLR-------DRVQHLQNELIRKNDREKELLLLYQAQQPQAALL 537
S +QK+L E + +LR D + L+ N KE L + + L
Sbjct: 1682 AKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKE--ELERVKMEYETLS 1739
Query: 538 KQYQGKLQKMKALEETVRHQEKVIE 562
K++Q + + +L E V+ + IE
Sbjct: 1740 KKFQSLMSEKDSLSEEVQDLKHQIE 1764
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 49.3 bits (116), Expect = 1e-05
Identities = 80/377 (21%), Positives = 155/377 (41%), Gaps = 66/377 (17%)
Query: 423 VPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQE----------- 471
+ E + ++ R M ++ ED++S RR++ + E E R SRLA +E
Sbjct: 552 IKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELR--ESRLAAEEFKRKATECQHK 609
Query: 472 --EEEGQGKASEAQ----NTVSMKQKLLLSELD------MKKLRDRVQHLQNELIRKNDR 519
+ + QGK + ++ +Q+L + EL +K + + LQN K
Sbjct: 610 LLKAKDQGKPEVGEYAKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERA 669
Query: 520 EKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVR------------------HQEKVI 561
E+EL L + + K KL + + LEE R H E+ I
Sbjct: 670 ERELEKLQNREDSSEGIRK----KLVEAEELEEKHREAQVSAQHLEVHLKQKEQHYEEKI 725
Query: 562 EKMERVLEDRLQDR-SKPPPLNRQQGKPYTGFPMLSASGLPLGSMG------ENLPVELY 614
+ ++ ++ L D+ + + R + + + +LS + +M E VEL
Sbjct: 726 KVLDNQIKKDLADKETLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELS 785
Query: 615 SV-LLAENAKLRTELD-KNRHQQAPIILQQQALPDLLSGTSDKFN-----LLAKLEHA-- 665
LA N+ L T+ + K + + + QQ+ + +G + N L K+ H
Sbjct: 786 EANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDH 845
Query: 666 --QSRILSLESQLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPSALTHSMDLK 723
++R+L LE++L + + +K +L +L E + + + + Q + L+
Sbjct: 846 SDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLR 905
Query: 724 Q-PSELEPLLPSSDSKL 739
Q +ELE ++ ++
Sbjct: 906 QAKTELEETTAEAEEEI 922
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 48.9 bits (115), Expect = 2e-05
Identities = 56/291 (19%), Positives = 124/291 (42%), Gaps = 29/291 (9%)
Query: 415 REAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASIL---EGENRILRSRLAQQE 471
+E EE+ E + RR + M E +RRQ ++ E + R L ++ +QE
Sbjct: 298 QEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 357
Query: 472 EEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDR--EKELLLLYQA 529
+ Q + + + + ++K E M + ++++ Q E IR+ + +++ + +
Sbjct: 358 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE-QEEKIREQEEMMQEQEEKMGEQ 416
Query: 530 QQPQAALLKQYQGKLQKMKALEETVRHQEKVI-EKMERVLEDRLQDRSKPPPLNRQQGKP 588
++ ++ Q + +KM+ EE +R QEK I E+ E++ E + + + Q+GK
Sbjct: 417 EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGK- 475
Query: 589 YTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPDL 648
E + + + K+R + +K R Q+ I Q++ + +
Sbjct: 476 ---------------------MCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 514
Query: 649 LSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQEK 699
++ + + E + E+ RR + ++ RL++QE+
Sbjct: 515 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEE 565
Score = 40.0 bits (92), Expect = 0.008
Identities = 30/159 (18%), Positives = 75/159 (47%), Gaps = 8/159 (5%)
Query: 416 EAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEG 475
E EE+ E + RR +K+ E +R Q + + +++ +QEE+ G
Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ----EQEEKMG 470
Query: 476 QGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHL--QNELIRKNDR--EKELLLLYQAQQ 531
+ + + M+++ +K+R++ + + Q E IR+ + +++ +++ ++
Sbjct: 471 EQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 530
Query: 532 PQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLED 570
++ Q + +KM+ EE +R QE + + E +++
Sbjct: 531 KMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 38.5 bits (88), Expect = 0.023
Identities = 61/305 (20%), Positives = 121/305 (39%), Gaps = 48/305 (15%)
Query: 447 LSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRV 506
L+ R A LE + R+ + +E +E K +++KL L E + +++ V
Sbjct: 186 LTKERDALSLE----LYRNTITDEELKEKNAK---------LQEKLQLVESEKSEIQLNV 232
Query: 507 QHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKAL---------------E 551
+ EL RK +R K LL Q Q L K+ Q K++A E
Sbjct: 233 K----ELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 288
Query: 552 ETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPV 611
+ R +EK+ E+ E++ E + R + + RQ+ + + + E +
Sbjct: 289 KMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK--I 346
Query: 612 ELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDKFNLLAKLEHAQSRILS 671
+ E K+R + +K + ++ I +Q+ + + + K+ + +I
Sbjct: 347 RELEEKMHEQEKIREQEEKRQEEEK--IREQEKRQE---QEAKMWRQEEKIREQEEKIRE 401
Query: 672 LESQLEDSARRWGREKQDL---ATRLQEQEKGFRHPSNSI------IIEQPSALTHSMDL 722
E +++ + G +++ + +QEQE+ R I I EQ + ++
Sbjct: 402 QEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 461
Query: 723 KQPSE 727
Q E
Sbjct: 462 MQEQE 466
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 48.5 bits (114), Expect = 2e-05
Identities = 132/567 (23%), Positives = 226/567 (39%), Gaps = 110/567 (19%)
Query: 222 ASVGLPITPLSFP---IPSMMNFDVPRVSQNGCPQLSKPGGPPEQPLWNQSFLFQGRDGA 278
A+ G + PL P +PS+ +P + + L P P + L G G
Sbjct: 143 ATSGTNLPPLMMPTPLVPSVSTSSLPNGTASLIQPLPIPYSSSTLPHGSSYSLMMGGFGG 202
Query: 279 TSFSEDTALV-LEYYSSTS----MKGSQP------WTLNQPLGISVLPLKSRLYQKMLTG 327
S + +L+ L SSTS + G+ P W + QP + K K ++G
Sbjct: 203 ASIQKAQSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPTRLKYRQ-KFNTLDKSMSG 261
Query: 328 KGLDGLHVERLPIMD----TSLKTINDEAPTVALSFQLLSSERPENFLTPNNSKA---LP 380
L G + T L TI A V QL + E + +KA LP
Sbjct: 262 Y-LSGFQARNALLQSNLSQTQLATIWTLAD-VDGDGQLKAEEFILAMHLTDMAKAGQPLP 319
Query: 381 -TLDPKILDKKLRTIQESWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAM 439
TL P+++ R ++ D+++ T+ S +E E + +P D NY R
Sbjct: 320 LTLPPELVPPSFRGGKQI---DSINGTLP-SYQKMQEEEPQKKLPVTFEDKRKANYERGN 375
Query: 440 QKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQ----KLLLS 495
++ + RRQA ++E + R R AQ+E+EE + K E Q KQ K L
Sbjct: 376 MELEK-----RRQA-LMEQQQREAE-RKAQKEKEEWERKQRELQEQEWKKQLELEKRLEK 428
Query: 496 ELDMKKLRD----------------------------RVQHL-------QNELIRKNDRE 520
+ ++++ R+ R Q L Q E++R N ++
Sbjct: 429 QRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRLNSKK 488
Query: 521 KELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEK------ME-RVLEDRLQ 573
K L L +A + +Q G+LQ ++ ++T + + +V++K ME + L+ LQ
Sbjct: 489 KNLHLELEALNGKH---QQISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEIKQLQQELQ 545
Query: 574 DRS--------KPPPLNRQ------QGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLA 619
+ + LN + P +G +L L + + L +L L
Sbjct: 546 EYQNKLIYLVPEKQLLNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQL-DALEK 604
Query: 620 ENAKLRTELDKNRHQ----QAPIILQQQALPDLLSGTSDKFNLLAKLEHAQSRILSLESQ 675
E A +E+D +Q + QQ AL L DK L ++E + ++ +
Sbjct: 605 ETASKLSEMDSFNNQLKELRETYNTQQLALEQLYKIKRDK---LKEIERKRLELMQKKKL 661
Query: 676 LEDSARRWGREKQDL---ATRLQEQEK 699
+++AR+ + K++L R +E+EK
Sbjct: 662 EDEAARKAKQGKENLWKENLRKEEEEK 688
Score = 32.3 bits (72), Expect = 1.7
Identities = 27/130 (20%), Positives = 63/130 (48%), Gaps = 16/130 (12%)
Query: 430 TEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMK 489
+EM+++ ++++ E + Q LE +I R +L + E + + +
Sbjct: 611 SEMDSFNNQLKELRE---TYNTQQLALEQLYKIKRDKLKEIERKR-----------LELM 656
Query: 490 QKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKA 549
QK L + +K + ++L E +RK + EK+ L Q ++ Q + ++ + +K +
Sbjct: 657 QKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRL--QEEKTQEKIQEEERKAEEKQRK 714
Query: 550 LEETVRHQEK 559
++T++ +EK
Sbjct: 715 DKDTLKAEEK 724
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 48.1 bits (113), Expect = 3e-05
Identities = 68/301 (22%), Positives = 129/301 (42%), Gaps = 38/301 (12%)
Query: 416 EAEEEPLVPEMSHDTEMNNYRRA------MQKMAEDILSLRRQASILEGENRILRSRLA- 468
+ EEE L+ E + R +Q+ E +L R+ L+ R R
Sbjct: 997 QQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEEL 1056
Query: 469 QQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQ 528
QQEEE+ G+ E + ++++ E ++++ +++ + E R+ +RE++ +
Sbjct: 1057 QQEEEQLLGEERETRRRQELERQYRKEE-ELQQEEEQLLREEPEKRRRQERERQCREEEE 1115
Query: 529 AQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKP 588
QQ + LL++ + K ++ + LE R +E+V ++ E++L + + R + L RQ +
Sbjct: 1116 LQQEEEQLLREEREKRRRQE-LERQYREEEEVQQEEEQLLREEPEKRRRQE-LERQYREE 1173
Query: 589 YTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQ--QALP 646
E L E +L E K R E ++ ++ + Q+ Q
Sbjct: 1174 ------------------EELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYR 1215
Query: 647 DLLSGTSDKFNLLAKLEHA--------QSRILSLESQLEDSARRWGREKQDLATRLQEQE 698
D + K+ + E+A + R QLEDS R + +QDL L EQ+
Sbjct: 1216 DEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQ 1275
Query: 699 K 699
+
Sbjct: 1276 E 1276
Score = 40.0 bits (92), Expect = 0.008
Identities = 61/318 (19%), Positives = 128/318 (40%), Gaps = 46/318 (14%)
Query: 415 REAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEE 474
R+ E+ +PE + RR +K + LE E ++ R AQQ +EE
Sbjct: 803 RQQREQRFLPEEEEKEQRRRQRREREK----------ELQFLEEEEQLQRRERAQQLQEE 852
Query: 475 GQGKASEAQNTVSMKQKLLLSELDMK---KLRDRVQHLQNELIRKNDREKELLLLYQAQQ 531
G + + S +Q+ D K +L + + ++ L K +++L Q Q
Sbjct: 853 EDGLQEDQERRRSQEQR-----RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQ 907
Query: 532 PQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTG 591
+ L++ + + ++ + E R +E++ ++ E++L + + R + +++ + Y
Sbjct: 908 EEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRR-----QERERQYRK 962
Query: 592 FPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSG 651
L + LL E + R ++ + + LQQ+ LL
Sbjct: 963 DKKLQ---------------QKEEQLLGEEPEKRRRQEREKKYREEEELQQEE-EQLLRE 1006
Query: 652 TSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIE 711
+K + R + +L+ + RE+++ RLQE+E+ +R + E
Sbjct: 1007 EREK-----RRRQEWERQYRKKDELQQEEEQLLREERE-KRRLQERERQYRE-EEELQQE 1059
Query: 712 QPSALTHSMDLKQPSELE 729
+ L + ++ ELE
Sbjct: 1060 EEQLLGEERETRRRQELE 1077
Score = 39.7 bits (91), Expect = 0.010
Identities = 56/297 (18%), Positives = 124/297 (41%), Gaps = 31/297 (10%)
Query: 436 RRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLS 495
RR ++ E L + + L+ R + +QEE Q E + + +++
Sbjct: 508 RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL 567
Query: 496 ELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVR 555
+ + ++ RD++ L R+ +R ++ L Q ++ + L ++ +L++ + E+ ++
Sbjct: 568 KREQEERRDQL------LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLK 621
Query: 556 HQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYS 615
+E E+ +++L+ Q+ + L R+Q + + L E
Sbjct: 622 REEPEEERRQQLLKSEEQEERRQQQLRREQQE----------------RREQRLKREEEE 665
Query: 616 VLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSD-KFNLLAKLEHAQSRILSLES 674
L + K R ++ R Q+ Q+QA + S ++ L ++ + QS++ S
Sbjct: 666 ERLEQRLK-REHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPR 724
Query: 675 QLEDSARRWGRE----KQDLATRLQEQEKGFRHPSNSIIIEQPSALTHSMDLKQPSE 727
+ E RR +E +++ + QE+E+ R EQ T ++ SE
Sbjct: 725 KQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE---EQRRDFTWQWQAEEKSE 778
Score = 38.9 bits (89), Expect = 0.018
Identities = 71/357 (19%), Positives = 140/357 (39%), Gaps = 50/357 (14%)
Query: 360 QLLSSERPENFLTPNNSKALPTLDPKILDKKLRTIQESWSKDTVSSTMDLSTSTPREAEE 419
Q L +R F + D K +++ + ++ + + L R+ E
Sbjct: 1406 QQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFRE 1465
Query: 420 EPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQ---EEEEGQ 476
E + + + +++ R +K E+ LRRQ + + LRS+ ++ EEE+
Sbjct: 1466 EEQLLQEREEQQLHRQERD-RKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524
Query: 477 GKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAAL 536
+ + + +Q+L E ++ +DR + + E + +RE++ L
Sbjct: 1525 HRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQL------------ 1572
Query: 537 LKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLS 596
Q + +K + E+ VR QE+ + ME E +L+ + L +++ + + L
Sbjct: 1573 --SRQERDRKFRLEEQKVRRQEQERKFMED--EQQLRRQEGQQQLRQERDRKFREDEQL- 1627
Query: 597 ASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDKF 656
+ E +L+ R E D+ ++ P + +Q+ L KF
Sbjct: 1628 --------LQEREEQQLH----------RQERDRKFLEEEPQLRRQEREQQLRHDRDRKF 1669
Query: 657 ----NLLAKLEHAQSRILSLESQL---EDSARRWGREK----QDLATRLQEQEKGFR 702
LL + E Q R + + E RR RE+ ++ R QE E+ FR
Sbjct: 1670 REEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFR 1726
Score = 36.6 bits (83), Expect = 0.088
Identities = 41/199 (20%), Positives = 85/199 (42%), Gaps = 9/199 (4%)
Query: 388 DKKLRTIQESWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYR-RAMQKMAEDI 446
+++LR Q+ + + L E+E E H+ E R + Q+ D
Sbjct: 398 EQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDW 457
Query: 447 LSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRV 506
L + E E R + +L + +EEE + + + + +Q+ E ++LR
Sbjct: 458 LKREEETERHEQERR--KQQLKRDQEEERRERWLKLEEEERREQQ----ERREQQLRREQ 511
Query: 507 QHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMER 566
+ + + +++ + E+ L +++Q +Q + + Q +K EE QE+ ++++R
Sbjct: 512 EERREQRLKRQEEEERLQQRLRSEQQLRR--EQEERREQLLKREEEKRLEQERREQRLKR 569
Query: 567 VLEDRLQDRSKPPPLNRQQ 585
E+R K RQQ
Sbjct: 570 EQEERRDQLLKREEERRQQ 588
Score = 35.8 bits (81), Expect = 0.15
Identities = 42/191 (21%), Positives = 86/191 (45%), Gaps = 28/191 (14%)
Query: 415 REAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRR------QASILEGENRIL----- 463
R AEEE L H+TE + Q ++L LRR Q E ++R+
Sbjct: 186 RRAEEEQLQSCKGHETE--EFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEE 243
Query: 464 -----RSRLAQQEEEEGQGKASEAQNTVSMKQKLL--LSELDMKKLRDRVQHLQNELIRK 516
R + ++EEE+ Q + + Q + +++ L L ++++ R + Q L R+
Sbjct: 244 KEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE 303
Query: 517 ND--REKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQD 574
R++E + ++ Q +Q + + Q+ + E+ +R +++ E+ E+ L ++
Sbjct: 304 QQLRRKQE----EERREQQEERREQQERREQQEERREQQLRREQE--ERREQQLRREQEE 357
Query: 575 RSKPPPLNRQQ 585
+ L R+Q
Sbjct: 358 ERREQQLRREQ 368
Score = 34.3 bits (77), Expect = 0.44
Identities = 34/158 (21%), Positives = 69/158 (43%), Gaps = 8/158 (5%)
Query: 429 DTEMNNYRRAMQKMAEDILSLR-RQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVS 487
D + + +Q+ E L + R LE E ++ R QQ + K E + +
Sbjct: 1618 DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQ 1677
Query: 488 MKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKM 547
++ L + RDR + + +R+ +RE++ L Q + Q K + + +
Sbjct: 1678 EGEEQQLRRQE----RDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQ 1733
Query: 548 KALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQ 585
+ +E +R QE+ + +E E++L+ + L RQ+
Sbjct: 1734 ETEQEQLRRQERYRKILE---EEQLRPEREEQQLRRQE 1768
Score = 33.5 bits (75), Expect = 0.75
Identities = 35/146 (23%), Positives = 68/146 (46%), Gaps = 8/146 (5%)
Query: 431 EMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQ 490
E RR Q+ E R Q E E R +L +++EEE + + + ++
Sbjct: 316 EQQEERREQQERREQQEERREQQLRREQEER-REQQLRREQEEERREQQLRREQEEERRE 374
Query: 491 KLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKAL 550
+ L E ++ R Q L+ E ++ RE++L Q ++ Q +Q + Q+++
Sbjct: 375 QQLRREQQLR----REQQLRRE--QQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428
Query: 551 EETVRHQEK-VIEKMERVLEDRLQDR 575
+E RH++K E+ E+ L+ ++R
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEER 454
Score = 31.6 bits (70), Expect = 2.8
Identities = 42/200 (21%), Positives = 77/200 (38%), Gaps = 18/200 (9%)
Query: 388 DKKLRTIQESWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAMQKMAEDIL 447
D +LR Q S+ + + RE E H E R QK A+
Sbjct: 1255 DSQLRDRQ---SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAK--- 1308
Query: 448 SLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMK--QKLLLSELDMKKLRDR 505
RR E + + R ++ +E K E + + + Q L E D K +
Sbjct: 1309 --RRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEE 1366
Query: 506 VQHLQN--------ELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQ 557
++H + + +R+ +RE++ L Q + Q + Q + +K + E+ + Q
Sbjct: 1367 LRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQ 1426
Query: 558 EKVIEKMERVLEDRLQDRSK 577
E+ + E + R Q+R +
Sbjct: 1427 ERDRKFREEEQQVRRQERER 1446
Score = 31.6 bits (70), Expect = 2.8
Identities = 37/177 (20%), Positives = 77/177 (43%), Gaps = 21/177 (11%)
Query: 413 TPREAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEE 472
T R+ EE + + + + R + E++ + LE E R+ R +E
Sbjct: 1334 TDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR------QE 1387
Query: 473 EEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHL-----------QNELIRKNDREK 521
E + E Q +++ L + D +K R+ Q L + + +R+ +RE+
Sbjct: 1388 RERKFLKEEQQLRCQEREQQLRQDRD-RKFREEEQQLSRQERDRKFREEEQQVRRQERER 1446
Query: 522 ELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRH-QEKVIEKMERVLEDRLQDRSK 577
+ L + QQ + ++++ + Q ++ EE H QE+ + +E + R Q+R +
Sbjct: 1447 K--FLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDR 1501
Score = 31.2 bits (69), Expect = 3.7
Identities = 39/179 (21%), Positives = 81/179 (45%), Gaps = 20/179 (11%)
Query: 418 EEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQE--EEEG 475
EEEP + + ++ + R + E +L EGE + LR + ++ EEE
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQ--------EGEEQQLRRQERDRKFREEEQ 1698
Query: 476 QGKASEAQNT-VSMKQKLLLSELDMKKLRDRV---QHLQNELIRKNDREKELL---LLYQ 528
Q + E + + +Q+L EL+ +K R+ Q + E +R+ +R +++L L
Sbjct: 1699 QLRRQERERKFLQEEQQLRRQELE-RKFREEEQLRQETEQEQLRRQERYRKILEEEQLRP 1757
Query: 529 AQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVL--EDRLQDRSKPPPLNRQQ 585
++ Q ++ K ++ + L + Q+ ++ +R E++L+ + L QQ
Sbjct: 1758 EREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQ 1816
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 47.8 bits (112), Expect = 4e-05
Identities = 136/565 (24%), Positives = 229/565 (40%), Gaps = 81/565 (14%)
Query: 222 ASVGLPITPLSFP---IPSMMNFDVPRVSQNGCPQLSKPGGPPEQPLWNQSFLFQGRDGA 278
A+ G + PL P +PS+ +P + + L P P + L G G
Sbjct: 143 ATSGTNLPPLMMPTPLVPSVSTSSLPNGTASLIQPLPIPYSSSTLPHGSSYSLMMGGFGG 202
Query: 279 TSFSEDTALV-LEYYSSTS----MKGSQP------WTLNQPLGISVLPLKSRLYQKMLTG 327
S + +L+ L SSTS + G+ P W + QP + K K ++G
Sbjct: 203 ASIQKAQSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPTRLKYRQ-KFNTLDKSMSG 261
Query: 328 KGLDGLHVERLPIMD----TSLKTINDEAPTVALSFQLLSSERPENFLTPNNSKA---LP 380
L G + T L TI A V QL + E + +KA LP
Sbjct: 262 Y-LSGFQARNALLQSNLSQTQLATIWTLAD-VDGDGQLKAEEFILAMHLTDMAKAGQPLP 319
Query: 381 -TLDPKILDKKLRTIQESWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAM 439
TL P+++ R ++ D+++ T+ S +E E + +P D NY R
Sbjct: 320 LTLPPELVPPSFRGGKQI---DSINGTLP-SYQKMQEEEPQKKLPVTFEDKRKANYERGN 375
Query: 440 QKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDM 499
++ + RRQA ++E + R R AQ+E+EE + K E Q KQ L++
Sbjct: 376 MELEK-----RRQA-LMEQQQREAE-RKAQKEKEEWERKQRELQEQEWKKQ------LEL 422
Query: 500 KKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALE-ETVRHQE 558
+K ++ + L+ + R+ +R K++ A+Q +L++ + LE E +R QE
Sbjct: 423 EKRLEKQRELERQ--REEERRKDIERREAAKQ-----------ELERQRRLEWERIRRQE 469
Query: 559 KVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLL 618
++ + R E+ ++ SK L+ + L A L + + L V L
Sbjct: 470 -LLNQKNREQEEIVRLNSKKKNLHLE----------LEA----LNGKHQQISGRLQDVRL 514
Query: 619 AENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDK-FNLLAKLEHAQSRILSLE-SQL 676
+ + +TEL+ Q I++ + L L +K L+ + + RI +++ S
Sbjct: 515 KKQTQ-KTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSNT 573
Query: 677 EDSA----RRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPSALTHSMDLKQPSELEPLL 732
DS + EK++L RL+EQ + S + E S + L
Sbjct: 574 PDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKCGNMDDSVLQCL 633
Query: 733 PSSDSKLNK---PLSPQKETANSQQ 754
S S LN L +ET N+QQ
Sbjct: 634 LSLLSCLNNLFLLLKELRETYNTQQ 658
Score = 31.6 bits (70), Expect = 2.8
Identities = 42/208 (20%), Positives = 97/208 (46%), Gaps = 26/208 (12%)
Query: 362 LSSERPENFL---TPNNSKAL---PTLDPKILDKKLRTIQESWSKDTVSSTMDLSTSTPR 415
L +ER +N TP++ +L +L+ + L ++L+ ++ K+T S ++ + +
Sbjct: 560 LLNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNNQ 619
Query: 416 ----EAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQE 471
++ L +S + +NN ++++ E + Q LE +I R +L + E
Sbjct: 620 LKCGNMDDSVLQCLLSLLSCLNNLFLLLKELRE---TYNTQQLALEQLYKIKRDKLKEIE 676
Query: 472 EEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQ 531
+ + + QK L + +K + ++L E +RK + EK+ L Q ++
Sbjct: 677 RKR-----------LELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRL--QEEK 723
Query: 532 PQAALLKQYQGKLQKMKALEETVRHQEK 559
Q + ++ + +K + ++T++ +EK
Sbjct: 724 TQEKIQEEERKAEEKQRKDKDTLKAEEK 751
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 47.8 bits (112), Expect = 4e-05
Identities = 136/565 (24%), Positives = 229/565 (40%), Gaps = 81/565 (14%)
Query: 222 ASVGLPITPLSFP---IPSMMNFDVPRVSQNGCPQLSKPGGPPEQPLWNQSFLFQGRDGA 278
A+ G + PL P +PS+ +P + + L P P + L G G
Sbjct: 143 ATSGTNLPPLMMPTPLVPSVSTSSLPNGTASLIQPLPIPYSSSTLPHGSSYSLMMGGFGG 202
Query: 279 TSFSEDTALV-LEYYSSTS----MKGSQP------WTLNQPLGISVLPLKSRLYQKMLTG 327
S + +L+ L SSTS + G+ P W + QP + K K ++G
Sbjct: 203 ASIQKAQSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPTRLKYRQ-KFNTLDKSMSG 261
Query: 328 KGLDGLHVERLPIMD----TSLKTINDEAPTVALSFQLLSSERPENFLTPNNSKA---LP 380
L G + T L TI A V QL + E + +KA LP
Sbjct: 262 Y-LSGFQARNALLQSNLSQTQLATIWTLAD-VDGDGQLKAEEFILAMHLTDMAKAGQPLP 319
Query: 381 -TLDPKILDKKLRTIQESWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAM 439
TL P+++ R ++ D+++ T+ S +E E + +P D NY R
Sbjct: 320 LTLPPELVPPSFRGGKQI---DSINGTLP-SYQKMQEEEPQKKLPVTFEDKRKANYERGN 375
Query: 440 QKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDM 499
++ + RRQA ++E + R R AQ+E+EE + K E Q KQ L++
Sbjct: 376 MELEK-----RRQA-LMEQQQREAE-RKAQKEKEEWERKQRELQEQEWKKQ------LEL 422
Query: 500 KKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALE-ETVRHQE 558
+K ++ + L+ + R+ +R K++ A+Q +L++ + LE E +R QE
Sbjct: 423 EKRLEKQRELERQ--REEERRKDIERREAAKQ-----------ELERQRRLEWERIRRQE 469
Query: 559 KVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLL 618
++ + R E+ ++ SK L+ + L A L + + L V L
Sbjct: 470 -LLNQKNREQEEIVRLNSKKKNLHLE----------LEA----LNGKHQQISGRLQDVRL 514
Query: 619 AENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDK-FNLLAKLEHAQSRILSLE-SQL 676
+ + +TEL+ Q I++ + L L +K L+ + + RI +++ S
Sbjct: 515 KKQTQ-KTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSNT 573
Query: 677 EDSA----RRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPSALTHSMDLKQPSELEPLL 732
DS + EK++L RL+EQ + S + E S + L
Sbjct: 574 PDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKCGNMDDSVLQCL 633
Query: 733 PSSDSKLNK---PLSPQKETANSQQ 754
S S LN L +ET N+QQ
Sbjct: 634 LSLLSCLNNLFLLLKELRETYNTQQ 658
Score = 31.6 bits (70), Expect = 2.8
Identities = 42/208 (20%), Positives = 97/208 (46%), Gaps = 26/208 (12%)
Query: 362 LSSERPENFL---TPNNSKAL---PTLDPKILDKKLRTIQESWSKDTVSSTMDLSTSTPR 415
L +ER +N TP++ +L +L+ + L ++L+ ++ K+T S ++ + +
Sbjct: 560 LLNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNNQ 619
Query: 416 ----EAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQE 471
++ L +S + +NN ++++ E + Q LE +I R +L + E
Sbjct: 620 LKCGNMDDSVLQCLLSLLSCLNNLFLLLKELRE---TYNTQQLALEQLYKIKRDKLKEIE 676
Query: 472 EEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQ 531
+ + + QK L + +K + ++L E +RK + EK+ L Q ++
Sbjct: 677 RKR-----------LELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRL--QEEK 723
Query: 532 PQAALLKQYQGKLQKMKALEETVRHQEK 559
Q + ++ + +K + ++T++ +EK
Sbjct: 724 TQEKIQEEERKAEEKQRKDKDTLKAEEK 751
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 47.4 bits (111), Expect = 5e-05
Identities = 81/382 (21%), Positives = 157/382 (41%), Gaps = 68/382 (17%)
Query: 387 LDKKLRTIQESWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEM------NNYRRAMQ 440
LD++L+ +++ KD + + R+A+ L+ ++ D M ++
Sbjct: 323 LDERLQELEKI--KDLHMAEKTKLITQLRDAKN--LIEQLEQDKGMVIAETKRQMHETLE 378
Query: 441 KMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMK 500
E+I LR + + + LR +Q+E+ + E + +S QK +E +
Sbjct: 379 MKEEEIAQLRSRIKQMTTQGEELR----EQKEKSERAAFEELEKALSTAQK---TEEARR 431
Query: 501 KLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQ--- 557
KL+ + Q + I K E+ + L Q + + +KQ + K + E+ + Q
Sbjct: 432 KLKAEMDE-QIKTIEKTSEEERISL-----QQELSRVKQEVVDVMKKSSEEQIAKLQKLH 485
Query: 558 EKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVL 617
EK + + E+ L +LQ R + E V
Sbjct: 486 EKELARKEQELTKKLQTREREFQ-------------------------------EQMKVA 514
Query: 618 LAENAKLRTELDKNRHQQAPIILQQQALPD--LLSGTSDKF-NLLAKLEHAQSRILSLES 674
L ++ ++ + + QQ + L++ L +L+ + +K +L + E ++RIL LES
Sbjct: 515 LEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELES 574
Query: 675 QLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIE----QPSALTHSMDLKQPSELEP 730
LE S + + +DLA L E EK + ++++E + +L H D +L+
Sbjct: 575 SLEKSLQENKNQSKDLAVHL-EAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQV 633
Query: 731 L---LPSSDSKLNKPLSPQKET 749
L + KL + +KET
Sbjct: 634 LKQQYQTEMEKLREKCEQEKET 655
Score = 45.8 bits (107), Expect = 1e-04
Identities = 69/364 (18%), Positives = 159/364 (43%), Gaps = 35/364 (9%)
Query: 402 TVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENR 461
T T + E +E+ E + + E + ++ + ++ ++++ + +++S E +
Sbjct: 422 TAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSS----EEQ 477
Query: 462 ILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREK 521
I ++L + E+E K E + +++ ++ + + + ++L+ I + ++
Sbjct: 478 I--AKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLK---ISQEKEQQ 532
Query: 522 ELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEK-MERVL-EDRLQDRSKPP 579
E L L + + + A+L + + KL+ ++ ET R + +E +E+ L E++ Q +
Sbjct: 533 ESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAV 592
Query: 580 PLNRQQGKPYTGFP-MLSASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRH---QQ 635
L ++ K M+ L S+ L + +TE++K R Q+
Sbjct: 593 HLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQE 652
Query: 636 APIILQQQALPDLLSGTSDKFN--LLAKLEHAQSRILSLESQLEDSAR------------ 681
+L+ + + + ++ N L KL+ Q+ + SL S+L + +
Sbjct: 653 KETLLKDKEI--IFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVL 710
Query: 682 --RWGREKQDLATRLQEQEKGFRHPSNSIIIEQPSAL--THSMDLKQPSELEPLLPSSDS 737
+ + KQ+L ++ EQ+ + +SII E ++ T Q ++LE LL D
Sbjct: 711 KDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDK 770
Query: 738 KLNK 741
L +
Sbjct: 771 HLKE 774
Score = 41.6 bits (96), Expect = 0.003
Identities = 86/440 (19%), Positives = 184/440 (41%), Gaps = 57/440 (12%)
Query: 336 ERLPIMDTSLKTINDEAPTVALSFQLLSSERPENFLTPNNSKALPTLDPKILDKKLRTIQ 395
++L + S+ +N+E T + + E+ + + TL K+LD++ +
Sbjct: 929 QKLSAKEDSIHILNEEYET-----KFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKL-- 981
Query: 396 ESWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTE------MNNYRRAMQKMAEDILSL 449
K+ ++ ++LS +E + + EM+ ++ ++ E + +
Sbjct: 982 ---KKELENTALELSQ---KEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEV 1035
Query: 450 RRQASILEGENRILRSRLAQQEEE-----EGQGKASEAQNTVSMKQKLLLSELDMKKLRD 504
R+ L I +L QQ EE E Q + E Q +KQK+LL + +++
Sbjct: 1036 HRRE--LNDVISIWEKKLNQQAEELQEIHEIQLQEKE-QEVAELKQKILLFGCEKEEMNK 1092
Query: 505 RVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQK---------MKALEETVR 555
+ L+ E ++++ EL + + L Q + KL+ K+L+E
Sbjct: 1093 EITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTF 1152
Query: 556 HQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYS 615
QE+++E ++ + E +D+ K L + F L +S E+ +E
Sbjct: 1153 LQEQLVE-LKMLAE---EDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKK 1208
Query: 616 VLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDKFN-LLAKLEHAQSRILSLES 674
L+E ++ ++ + + L + +L++ +S K N +L+++ H Q R ++
Sbjct: 1209 --LSEELAIQLDICCKKTE----ALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKE 1262
Query: 675 QLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPSALTHSMDLKQPSELEPLLPS 734
L K + L+ Q + N++ I A TH ++ K+ ++++ +
Sbjct: 1263 AL--------LIKTCTVSELEAQLRQLTEEQNTLNISFQQA-THQLEEKE-NQIKSMKAD 1312
Query: 735 SDSKLNKPLSPQKETANSQQ 754
+S + + + QKE N QQ
Sbjct: 1313 IESLVTEKEALQKEGGNQQQ 1332
Score = 33.5 bits (75), Expect = 0.75
Identities = 39/199 (19%), Positives = 84/199 (42%), Gaps = 16/199 (8%)
Query: 382 LDPKILDKKLRTIQESWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAMQK 441
L K +++L+ +++ ++ + +L R+AE++ + ++M +K
Sbjct: 1613 LSVKSKEEELKALEDRLESESAAKLAELK----RKAEQKIAAIKKQLLSQMEEKEEQYKK 1668
Query: 442 MAEDILS-LRRQASILEGENRILRSRLAQQEEEEGQGKA--SEAQNTVSMKQKLLLSELD 498
E LS L + E E IL +L E + + A+N + ++ E D
Sbjct: 1669 GTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQ---EEAD 1725
Query: 499 MKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLK------QYQGKLQKMKALEE 552
+ + + ++++N EKE LL Q+ + + QYQ +L K++ E
Sbjct: 1726 SQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEA 1785
Query: 553 TVRHQEKVIEKMERVLEDR 571
+ +I ++ LE++
Sbjct: 1786 KQHEDQSMIGHLQEELEEK 1804
Score = 31.6 bits (70), Expect = 2.8
Identities = 43/242 (17%), Positives = 94/242 (38%), Gaps = 32/242 (13%)
Query: 341 MDTSLKTINDEAPTVALSFQLLSSERPENFLTPNNSKALPTLDPKILDKKLRTIQESWSK 400
++T L+ E + + + S + E + P ++K + + +E+ S+
Sbjct: 1677 LNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQ---------EEADSQ 1727
Query: 401 DTVSSTMDLSTSTPRE--AEEEPLVPEMSHDTE----------------MNNYRRAMQKM 442
V T + S + E+E L+ + + E + A K
Sbjct: 1728 GCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQ 1787
Query: 443 AEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVS-----MKQKLLLSEL 497
ED + LE +N+ +AQ E+EG +A+ + +++ L EL
Sbjct: 1788 HEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKEL 1847
Query: 498 DMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQ 557
+ L +++ L + L+R+ + + + ++ + L+Q G+ + + LEE +
Sbjct: 1848 TCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEK 1907
Query: 558 EK 559
K
Sbjct: 1908 SK 1909
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 47.4 bits (111), Expect = 5e-05
Identities = 61/289 (21%), Positives = 125/289 (43%), Gaps = 50/289 (17%)
Query: 428 HDTEMNNYRRAMQKMAE--DILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNT 485
+D E+ R ++++ + ++L+ R S + +R +L Q+E E+ QG++ E +
Sbjct: 785 YDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERR 844
Query: 486 VSMKQKLL--------LSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALL 537
V+ Q+ + ++ +KK ++ L+ L+ EKE + +A + + L
Sbjct: 845 VAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENE---L 901
Query: 538 KQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSA 597
+ QG L +T + Q+++ EK++ E + Q R + ++
Sbjct: 902 EAAQGN------LSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWH---------- 945
Query: 598 SGLPLGSMGENLPVELYSVLLAENA---KLRTELD----KNRHQQAPIILQQQALPDLLS 650
LG E L E+ ++ A +L+ +LD KNR + A +Q+Q L
Sbjct: 946 ----LGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAE--MQRQLKEKTLE 999
Query: 651 GTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQEK 699
++K L A + R+ +E+ R + R + + T+ Q E+
Sbjct: 1000 --AEKSRLTAMKMQDEMRL------MEEELRDYQRAQDEALTKRQLLEQ 1040
>gi|239745087 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 1 [Homo sapiens]
Length = 547
Score = 47.0 bits (110), Expect = 7e-05
Identities = 81/377 (21%), Positives = 159/377 (42%), Gaps = 58/377 (15%)
Query: 348 INDEAPTVALSFQLLSSERPENFLTPNNSKALPTLDPKILDKKLRTIQESWSKDTVSSTM 407
I+ E+PT + + + L S E + P++ R+++ S K+T+ S
Sbjct: 73 IHGESPTSSATLKDLESPCQELAVVPDS----------------RSVKVSQLKNTIKSLK 116
Query: 408 DLSTSTPREAEEEPLV----PEMSHDTEMNNYRRAMQK--MAEDILSLRRQASILEGENR 461
+ EEE + + E+ R +QK + D+ +R E E++
Sbjct: 117 QQKKQVVHQLEEEKKANNEKQKAERELEVQIQRLNIQKGKLNTDLYHTKRSLRYFEEESK 176
Query: 462 ILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDR---VQHLQNELIRKND 518
L RL + +G+ + + + T + K+K K R Q ++ + + K
Sbjct: 177 DLAVRLQHSLQRKGELERALSAVTATQKKKAERQFSSRSKARTEWKLEQSMREQALLKAQ 236
Query: 519 --REKELLLLYQAQQPQ-AALLK----QYQGKLQKMK----ALEETVRHQEKVIEKMERV 567
+ KE L Q ++ + A LK ++Q +++KM +L++ +H + +E +ER
Sbjct: 237 LTQLKESLKEVQLERDEYAEHLKGERARWQQRMRKMSQEVCSLKKEKKHDKYRVETLERS 296
Query: 568 LEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKL--- 624
L L Q +P P +P + ++L EL V A A++
Sbjct: 297 LS----------KLKNQMAEPLPPEP----PAVPSEAELQHLRKELERVAGALQAQVEYN 342
Query: 625 -RTELDKNRHQQAPIILQQQALP---DLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSA 680
R L N Q+ + QQ+ LP + L ++ N +L + +L LE Q+++
Sbjct: 343 QRISL-LNEGQKERLREQQERLPEQEERLQQLAEPQNSFKELNNENKSVLQLEQQVKELQ 401
Query: 681 RRWGREKQDLATRLQEQ 697
+ G+E+ + A++ ++Q
Sbjct: 402 EKLGKERLEAASQQKQQ 418
>gi|39930479 DIX domain containing 1 isoform b [Homo sapiens]
Length = 472
Score = 46.6 bits (109), Expect = 9e-05
Identities = 45/170 (26%), Positives = 82/170 (48%), Gaps = 29/170 (17%)
Query: 409 LSTSTPREAEEEPLV-------PE---MSHDTEMNNYRRAMQKMAEDILSLRRQASILEG 458
L+ S P + +E PL PE + + ++ Q + +++L +++A L+G
Sbjct: 99 LNGSLPEDEQERPLALCEPGVNPEEQLIIIQSRLDQSMEENQDLKKELLKCKQEARNLQG 158
Query: 459 ENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQN-ELIRKN 517
L+ RL QQ+ + + +KQ+LL + +D +L H QN +L RK
Sbjct: 159 IKDALQQRLTQQD-----------TSVLQLKQELLRANMDKDEL-----HNQNVDLQRKL 202
Query: 518 DREKELLLLYQAQQPQA-ALLKQYQGKLQK-MKALEETVRHQEKVIEKME 565
D LL Y+ + Q LL+Q+Q KL++ ++ L + HQ + ++E
Sbjct: 203 DERNRLLGEYKKELGQKDRLLQQHQAKLEEALRKLSDVSYHQVDLERELE 252
>gi|83816971 DIX domain containing 1 isoform a [Homo sapiens]
Length = 683
Score = 46.6 bits (109), Expect = 9e-05
Identities = 45/170 (26%), Positives = 82/170 (48%), Gaps = 29/170 (17%)
Query: 409 LSTSTPREAEEEPLV-------PE---MSHDTEMNNYRRAMQKMAEDILSLRRQASILEG 458
L+ S P + +E PL PE + + ++ Q + +++L +++A L+G
Sbjct: 310 LNGSLPEDEQERPLALCEPGVNPEEQLIIIQSRLDQSMEENQDLKKELLKCKQEARNLQG 369
Query: 459 ENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQN-ELIRKN 517
L+ RL QQ+ + + +KQ+LL + +D +L H QN +L RK
Sbjct: 370 IKDALQQRLTQQD-----------TSVLQLKQELLRANMDKDEL-----HNQNVDLQRKL 413
Query: 518 DREKELLLLYQAQQPQA-ALLKQYQGKLQK-MKALEETVRHQEKVIEKME 565
D LL Y+ + Q LL+Q+Q KL++ ++ L + HQ + ++E
Sbjct: 414 DERNRLLGEYKKELGQKDRLLQQHQAKLEEALRKLSDVSYHQVDLERELE 463
>gi|21687020 ecotropic viral integration site 5-like isoform 2 [Homo
sapiens]
Length = 794
Score = 46.2 bits (108), Expect = 1e-04
Identities = 86/402 (21%), Positives = 170/402 (42%), Gaps = 76/402 (18%)
Query: 362 LSSERPENFLTPNNSKALPTLDPKILDKKLRTIQESWSKDTVSSTMDLSTSTPREAEEEP 421
L +R E ++A + ++ ++L +++ S + + + + ST R+ +E+
Sbjct: 390 LLKQRIETLEKGQVTRAQEAEENYVIKRELAVVRQQCS--SAAEDLQKAQSTIRQLQEQQ 447
Query: 422 LVPEMSHD------TEMNNYRR-------AMQKMAEDILSLRRQASILEGENRILRSRLA 468
P ++ D TE+ R A+++M + +L + ++ S L EN + A
Sbjct: 448 ENPRLTEDFVSHLETELEQSRLRETETLGALREMQDKVLDMEKRNSSLPDENNV-----A 502
Query: 469 QQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQ-HLQNELIRKNDREKELLLLY 527
Q +EE K E Q S ++ +L +++L D Q HL + R KE
Sbjct: 503 QLQEELKALKVREGQAVASTREL----KLQLQELSDTWQAHLA-----RGGRWKE----- 548
Query: 528 QAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGK 587
P+ ++ + Q +L ++ E + + E +RV+E QD LNR + +
Sbjct: 549 ---SPRKLVVGELQDELMSVRLREAQALAEGR--ELRQRVVELETQDHIHRNLLNRVEAE 603
Query: 588 PYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPD 647
++ E L L A+N L+T+L ++R +QA + ++ +
Sbjct: 604 R--------------AALQEKL-----QYLAAQNKGLQTQLSESRRKQAE--AECKSKEE 642
Query: 648 LLSGTSDKFNLLAKLEHAQSRILSLESQLED----------SARRWGREKQDLATRLQEQ 697
+++ + + +A + + RI LE Q E+ + ++ RE +D L+ +
Sbjct: 643 VMAVRLREADSMAAVAEMRQRIAELEIQREEGRIQGQLNHSDSSQYIRELKDQIEELKAE 702
Query: 698 EKGFRHPSNSIIIEQPSALTHSMDLKQPSELEPLLPSSDSKL 739
+ + P E P A + L + + E LPSSD +L
Sbjct: 703 VRLLKGPPP---FEDPLAF-DGLSLARHLD-EDSLPSSDEEL 739
>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
sapiens]
Length = 1133
Score = 46.2 bits (108), Expect = 1e-04
Identities = 99/466 (21%), Positives = 171/466 (36%), Gaps = 65/466 (13%)
Query: 316 LKSRLYQKMLTGKGLDGLHVERLPIMDTSLKTINDEA-PTVALSFQLLSSERPENFLTPN 374
L RL ++ L K L VE+L +L+ + D + + L + E T
Sbjct: 399 LNKRLERETLQSKDFK-LEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQ 457
Query: 375 NSKALPTLDPKILDKKLRTIQESWSKDTVSSTMDLS---TSTPREAEEEPLVPEMSHDTE 431
S+ L +L +I K+L I+ K + DL+ T T +E + E TE
Sbjct: 458 LSQELESLKVRI--KELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTE 515
Query: 432 MNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQK 491
+ Q E ++E R L+S+ +E+ K + +K K
Sbjct: 516 DKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERD-----DLKNK 570
Query: 492 LLLSELDMKKLRDRVQHLQNELIRKNDREKELL-------------LLYQAQQPQAALLK 538
L E L RV L+N L EK+ L L+Q L +
Sbjct: 571 LKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQ 630
Query: 539 QYQG---KLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPML 595
+ + KL+ MKA+E+ + E E +ER + +R K L+++
Sbjct: 631 EVERLKLKLKDMKAIEDDLMKTEDEYETLERRYAN---ERDKAQFLSKEL---------- 677
Query: 596 SASGLPLGSMGENLPVELYSVLLAENAKLRTE------LDKNRHQQAPIILQQQALPDLL 649
E++ +EL LAE + E L + + + + AL + +
Sbjct: 678 -----------EHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDALKEKI 726
Query: 650 SGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQ---EKGFRHPSN 706
+L+ L+ S + +Q E+ R GRE ++L L+ K R N
Sbjct: 727 HEYMATEDLICHLQGDHSVLQKKLNQQENRNRDLGREIENLTKELERYRHFSKSLRPSLN 786
Query: 707 SIIIEQPSALTHSMDLK----QPSELEPLLPSSDSKLNKPLSPQKE 748
I P + + + +P + + L+P + +N L + E
Sbjct: 787 GRRISDPQVFSKEVQTEAVDNEPPDYKSLIPLERAVINGQLYEESE 832
Score = 35.0 bits (79), Expect = 0.26
Identities = 59/314 (18%), Positives = 131/314 (41%), Gaps = 40/314 (12%)
Query: 394 IQESWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQA 453
+QE K T + +T +++ ++ +++++ N R+ QK+A +L RQ
Sbjct: 281 VQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQN--RQLQQKLA----ALSRQI 334
Query: 454 SILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNEL 513
LE NR LR + EEE Q +K+K+ E + V+ L+ +
Sbjct: 335 DELEETNRSLR-----KAEEELQ----------DIKEKISKGEYGNAGIMAEVEELRKRV 379
Query: 514 IRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQ 573
+ +++EL+ + + + L++ + + K E + + +EK+E Q
Sbjct: 380 LDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQ 439
Query: 574 D-RSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTE----- 627
+ S L +++ + L E+L V + + E+ +TE
Sbjct: 440 ECYSLKCNLEKER-----------MTTKQLSQELESLKVRIKELEAIESRLEKTEFTLKE 488
Query: 628 -LDKNRHQQAPIILQQQALPDLLSGTSDKFNLL-AKLEHAQSRILSLESQLEDSARRWGR 685
L K + + +++ + + L T DK ++L+ Q+++ ++ +L + +R +
Sbjct: 489 DLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALK 548
Query: 686 EKQDLATRLQEQEK 699
K D+ ++ K
Sbjct: 549 SKTDVEEKMYSVTK 562
>gi|109659849 filamin A interacting protein 1-like isoform 2 [Homo
sapiens]
Length = 893
Score = 46.2 bits (108), Expect = 1e-04
Identities = 99/466 (21%), Positives = 171/466 (36%), Gaps = 65/466 (13%)
Query: 316 LKSRLYQKMLTGKGLDGLHVERLPIMDTSLKTINDEA-PTVALSFQLLSSERPENFLTPN 374
L RL ++ L K L VE+L +L+ + D + + L + E T
Sbjct: 159 LNKRLERETLQSKDFK-LEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQ 217
Query: 375 NSKALPTLDPKILDKKLRTIQESWSKDTVSSTMDLS---TSTPREAEEEPLVPEMSHDTE 431
S+ L +L +I K+L I+ K + DL+ T T +E + E TE
Sbjct: 218 LSQELESLKVRI--KELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTE 275
Query: 432 MNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQK 491
+ Q E ++E R L+S+ +E+ K + +K K
Sbjct: 276 DKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERD-----DLKNK 330
Query: 492 LLLSELDMKKLRDRVQHLQNELIRKNDREKELL-------------LLYQAQQPQAALLK 538
L E L RV L+N L EK+ L L+Q L +
Sbjct: 331 LKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQ 390
Query: 539 QYQG---KLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPML 595
+ + KL+ MKA+E+ + E E +ER + +R K L+++
Sbjct: 391 EVERLKLKLKDMKAIEDDLMKTEDEYETLERRYAN---ERDKAQFLSKEL---------- 437
Query: 596 SASGLPLGSMGENLPVELYSVLLAENAKLRTE------LDKNRHQQAPIILQQQALPDLL 649
E++ +EL LAE + E L + + + + AL + +
Sbjct: 438 -----------EHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDALKEKI 486
Query: 650 SGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQ---EKGFRHPSN 706
+L+ L+ S + +Q E+ R GRE ++L L+ K R N
Sbjct: 487 HEYMATEDLICHLQGDHSVLQKKLNQQENRNRDLGREIENLTKELERYRHFSKSLRPSLN 546
Query: 707 SIIIEQPSALTHSMDLK----QPSELEPLLPSSDSKLNKPLSPQKE 748
I P + + + +P + + L+P + +N L + E
Sbjct: 547 GRRISDPQVFSKEVQTEAVDNEPPDYKSLIPLERAVINGQLYEESE 592
Score = 35.0 bits (79), Expect = 0.26
Identities = 59/314 (18%), Positives = 131/314 (41%), Gaps = 40/314 (12%)
Query: 394 IQESWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQA 453
+QE K T + +T +++ ++ +++++ N R+ QK+A +L RQ
Sbjct: 41 VQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQN--RQLQQKLA----ALSRQI 94
Query: 454 SILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNEL 513
LE NR LR + EEE Q +K+K+ E + V+ L+ +
Sbjct: 95 DELEETNRSLR-----KAEEELQ----------DIKEKISKGEYGNAGIMAEVEELRKRV 139
Query: 514 IRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQ 573
+ +++EL+ + + + L++ + + K E + + +EK+E Q
Sbjct: 140 LDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQ 199
Query: 574 D-RSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTE----- 627
+ S L +++ + L E+L V + + E+ +TE
Sbjct: 200 ECYSLKCNLEKER-----------MTTKQLSQELESLKVRIKELEAIESRLEKTEFTLKE 248
Query: 628 -LDKNRHQQAPIILQQQALPDLLSGTSDKFNLL-AKLEHAQSRILSLESQLEDSARRWGR 685
L K + + +++ + + L T DK ++L+ Q+++ ++ +L + +R +
Sbjct: 249 DLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALK 308
Query: 686 EKQDLATRLQEQEK 699
K D+ ++ K
Sbjct: 309 SKTDVEEKMYSVTK 322
>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
sapiens]
Length = 1135
Score = 46.2 bits (108), Expect = 1e-04
Identities = 99/466 (21%), Positives = 171/466 (36%), Gaps = 65/466 (13%)
Query: 316 LKSRLYQKMLTGKGLDGLHVERLPIMDTSLKTINDEA-PTVALSFQLLSSERPENFLTPN 374
L RL ++ L K L VE+L +L+ + D + + L + E T
Sbjct: 399 LNKRLERETLQSKDFK-LEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQ 457
Query: 375 NSKALPTLDPKILDKKLRTIQESWSKDTVSSTMDLS---TSTPREAEEEPLVPEMSHDTE 431
S+ L +L +I K+L I+ K + DL+ T T +E + E TE
Sbjct: 458 LSQELESLKVRI--KELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTE 515
Query: 432 MNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQK 491
+ Q E ++E R L+S+ +E+ K + +K K
Sbjct: 516 DKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERD-----DLKNK 570
Query: 492 LLLSELDMKKLRDRVQHLQNELIRKNDREKELL-------------LLYQAQQPQAALLK 538
L E L RV L+N L EK+ L L+Q L +
Sbjct: 571 LKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQ 630
Query: 539 QYQG---KLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPML 595
+ + KL+ MKA+E+ + E E +ER + +R K L+++
Sbjct: 631 EVERLKLKLKDMKAIEDDLMKTEDEYETLERRYAN---ERDKAQFLSKEL---------- 677
Query: 596 SASGLPLGSMGENLPVELYSVLLAENAKLRTE------LDKNRHQQAPIILQQQALPDLL 649
E++ +EL LAE + E L + + + + AL + +
Sbjct: 678 -----------EHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDALKEKI 726
Query: 650 SGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQ---EKGFRHPSN 706
+L+ L+ S + +Q E+ R GRE ++L L+ K R N
Sbjct: 727 HEYMATEDLICHLQGDHSVLQKKLNQQENRNRDLGREIENLTKELERYRHFSKSLRPSLN 786
Query: 707 SIIIEQPSALTHSMDLK----QPSELEPLLPSSDSKLNKPLSPQKE 748
I P + + + +P + + L+P + +N L + E
Sbjct: 787 GRRISDPQVFSKEVQTEAVDNEPPDYKSLIPLERAVINGQLYEESE 832
Score = 35.0 bits (79), Expect = 0.26
Identities = 59/314 (18%), Positives = 131/314 (41%), Gaps = 40/314 (12%)
Query: 394 IQESWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQA 453
+QE K T + +T +++ ++ +++++ N R+ QK+A +L RQ
Sbjct: 281 VQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQN--RQLQQKLA----ALSRQI 334
Query: 454 SILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNEL 513
LE NR LR + EEE Q +K+K+ E + V+ L+ +
Sbjct: 335 DELEETNRSLR-----KAEEELQ----------DIKEKISKGEYGNAGIMAEVEELRKRV 379
Query: 514 IRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQ 573
+ +++EL+ + + + L++ + + K E + + +EK+E Q
Sbjct: 380 LDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQ 439
Query: 574 D-RSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTE----- 627
+ S L +++ + L E+L V + + E+ +TE
Sbjct: 440 ECYSLKCNLEKER-----------MTTKQLSQELESLKVRIKELEAIESRLEKTEFTLKE 488
Query: 628 -LDKNRHQQAPIILQQQALPDLLSGTSDKFNLL-AKLEHAQSRILSLESQLEDSARRWGR 685
L K + + +++ + + L T DK ++L+ Q+++ ++ +L + +R +
Sbjct: 489 DLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALK 548
Query: 686 EKQDLATRLQEQEK 699
K D+ ++ K
Sbjct: 549 SKTDVEEKMYSVTK 562
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 46.2 bits (108), Expect = 1e-04
Identities = 40/144 (27%), Positives = 78/144 (54%), Gaps = 26/144 (18%)
Query: 439 MQKMAEDI-LSLRRQASILEGENRILRSRLAQQEEEEG-QGKASEAQNTVSMKQKLLLSE 496
++K +D+ + L QA ++G+ L ++L + +EEEG Q KA EAQN + K+K
Sbjct: 1221 LEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEK----- 1275
Query: 497 LDMKKLRDRVQHLQ---NELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEET 553
+KL D++Q +Q + L ++ + E E+ ++ + + L + + LEE
Sbjct: 1276 ---EKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTL---------ENRDLEEE 1323
Query: 554 VRHQEKVIEKMERVLEDRLQDRSK 577
+ +++VI+K L+D+++ SK
Sbjct: 1324 LDMKDRVIKK----LQDQVKTLSK 1343
>gi|229577000 ecotropic viral integration site 5-like isoform 1
[Homo sapiens]
Length = 805
Score = 45.8 bits (107), Expect = 1e-04
Identities = 82/378 (21%), Positives = 162/378 (42%), Gaps = 76/378 (20%)
Query: 386 ILDKKLRTIQESWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHD------TEMNNYRR-- 437
++ ++L +++ S + + + + ST R+ +E+ P ++ D TE+ R
Sbjct: 425 VIKRELAVVRQQCS--SAAEDLQKAQSTIRQLQEQQENPRLTEDFVSHLETELEQSRLRE 482
Query: 438 -----AMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKL 492
A+++M + +L + ++ S L EN + AQ +EE K E Q S ++
Sbjct: 483 TETLGALREMQDKVLDMEKRNSSLPDENNV-----AQLQEELKALKVREGQAVASTREL- 536
Query: 493 LLSELDMKKLRDRVQ-HLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALE 551
+L +++L D Q HL + R KE P+ ++ + Q +L ++ E
Sbjct: 537 ---KLQLQELSDTWQAHLA-----RGGRWKE--------SPRKLVVGELQDELMSVRLRE 580
Query: 552 ETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPV 611
+ + E +RV+E QD LNR + + ++ E L
Sbjct: 581 AQALAEGR--ELRQRVVELETQDHIHRNLLNRVEAER--------------AALQEKL-- 622
Query: 612 ELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDKFNLLAKLEHAQSRILS 671
L A+N L+T+L ++R +QA + ++ ++++ + + +A + + RI
Sbjct: 623 ---QYLAAQNKGLQTQLSESRRKQAE--AECKSKEEVMAVRLREADSMAAVAEMRQRIAE 677
Query: 672 LESQLED----------SARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPSALTHSMD 721
LE Q E+ + ++ RE +D L+ + + + P E P A +
Sbjct: 678 LEIQREEGRIQGQLNHSDSSQYIRELKDQIEELKAEVRLLKGPPP---FEDPLAF-DGLS 733
Query: 722 LKQPSELEPLLPSSDSKL 739
L + + E LPSSD +L
Sbjct: 734 LARHLD-EDSLPSSDEEL 750
>gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]
Length = 971
Score = 45.8 bits (107), Expect = 1e-04
Identities = 87/354 (24%), Positives = 137/354 (38%), Gaps = 65/354 (18%)
Query: 399 SKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEG 458
+KD++ T D + E E+E E + + + KMA D+ + L
Sbjct: 470 TKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEI--KWTENLRQ 527
Query: 459 ENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKND 518
E LR L Q EE+ + +M Q L L + + RD Q +L+ +
Sbjct: 528 ECSKLREELRLQHEEDKKS---------AMSQLLQLKDREKNAARDSWQKKVEDLLNQIS 578
Query: 519 REKELLLLY------QAQQPQAALLKQYQGKLQKMKALEETVRHQEKVI----------- 561
K+ L + QQ QA ++ Q Q+++ LEE + + K +
Sbjct: 579 LLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTM 638
Query: 562 ----EKMERVLEDRLQDR--SKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYS 615
EK +R LE+ LQ + ++ L + GF + L + L EL
Sbjct: 639 EEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQEL------QTLRFELED 692
Query: 616 VLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDKFNLLAKLEHAQSRILSLESQ 675
A A LR+EL+ HQ A I DLL + AK+E LE
Sbjct: 693 EGKAMLASLRSELN---HQHAAAI-------DLLRHNHHQELAAAKME--------LERS 734
Query: 676 LEDSARRWGREKQDLATRLQEQEKGFRHPSNSI------IIEQPSALTHSMDLK 723
+ D +RR +E T LQE+ + H + + + E SALT ++ K
Sbjct: 735 I-DISRRQSKEHICRITDLQEELRHREHHISELDKEVQHLHENISALTKELEFK 787
Score = 37.7 bits (86), Expect = 0.040
Identities = 70/331 (21%), Positives = 133/331 (40%), Gaps = 56/331 (16%)
Query: 434 NYRRAMQKMAEDI----LSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQ--NTVS 487
N + +QK +D ++L + +E E R RL QQ+ + KAS
Sbjct: 215 NNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERL-QQQASDLVLKASHIGMLQATQ 273
Query: 488 MKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKM 547
M Q++ + +L+ +K R NE + + + E+ L + Q+ +Q Q L+
Sbjct: 274 MTQEVTIKDLESEKSR------VNERLSQLEEERAFL----RSKTQSLDEEQKQQILELE 323
Query: 548 KALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGE 607
K + E R Q++ E+ + L+ RL++ + LN K +
Sbjct: 324 KKVNEAKRTQQEYYERELKNLQSRLEE--EVTQLNEAHSKTLEEL-----------AWKH 370
Query: 608 NLPVE-LYSVLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDKFNLLAKLEHAQ 666
++ +E ++S + + KL+ +L++ ++ DK NL Q
Sbjct: 371 HMAIEAVHSNAIRDKKKLQMDLEEQHNK-------------------DKLNLEEDKNQLQ 411
Query: 667 SRILSLESQLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPS--ALTHSMDLKQ 724
+ +L+ LED +E L +++ E+G I Q S L + +DL +
Sbjct: 412 QELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTK 471
Query: 725 PSELEPLLPSSDSKLNKPLSPQKETANSQQT 755
S L + D+ LN ++E ++T
Sbjct: 472 DS----LKETKDALLNVEGELEQERQQHEET 498
>gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]
Length = 1140
Score = 45.8 bits (107), Expect = 1e-04
Identities = 87/354 (24%), Positives = 137/354 (38%), Gaps = 65/354 (18%)
Query: 399 SKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEG 458
+KD++ T D + E E+E E + + + KMA D+ + L
Sbjct: 590 TKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEI--KWTENLRQ 647
Query: 459 ENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKND 518
E LR L Q EE+ + +M Q L L + + RD Q +L+ +
Sbjct: 648 ECSKLREELRLQHEEDKKS---------AMSQLLQLKDREKNAARDSWQKKVEDLLNQIS 698
Query: 519 REKELLLLY------QAQQPQAALLKQYQGKLQKMKALEETVRHQEKVI----------- 561
K+ L + QQ QA ++ Q Q+++ LEE + + K +
Sbjct: 699 LLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTM 758
Query: 562 ----EKMERVLEDRLQDR--SKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYS 615
EK +R LE+ LQ + ++ L + GF + L + L EL
Sbjct: 759 EEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQEL------QTLRFELED 812
Query: 616 VLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDKFNLLAKLEHAQSRILSLESQ 675
A A LR+EL+ HQ A I DLL + AK+E LE
Sbjct: 813 EGKAMLASLRSELN---HQHAAAI-------DLLRHNHHQELAAAKME--------LERS 854
Query: 676 LEDSARRWGREKQDLATRLQEQEKGFRHPSNSI------IIEQPSALTHSMDLK 723
+ D +RR +E T LQE+ + H + + + E SALT ++ K
Sbjct: 855 I-DISRRQSKEHICRITDLQEELRHREHHISELDKEVQHLHENISALTKELEFK 907
Score = 37.7 bits (86), Expect = 0.040
Identities = 70/331 (21%), Positives = 133/331 (40%), Gaps = 56/331 (16%)
Query: 434 NYRRAMQKMAEDI----LSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQ--NTVS 487
N + +QK +D ++L + +E E R RL QQ+ + KAS
Sbjct: 335 NNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERL-QQQASDLVLKASHIGMLQATQ 393
Query: 488 MKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKM 547
M Q++ + +L+ +K R NE + + + E+ L + Q+ +Q Q L+
Sbjct: 394 MTQEVTIKDLESEKSR------VNERLSQLEEERAFL----RSKTQSLDEEQKQQILELE 443
Query: 548 KALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGE 607
K + E R Q++ E+ + L+ RL++ + LN K +
Sbjct: 444 KKVNEAKRTQQEYYERELKNLQSRLEE--EVTQLNEAHSKTLEEL-----------AWKH 490
Query: 608 NLPVE-LYSVLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSGTSDKFNLLAKLEHAQ 666
++ +E ++S + + KL+ +L++ ++ DK NL Q
Sbjct: 491 HMAIEAVHSNAIRDKKKLQMDLEEQHNK-------------------DKLNLEEDKNQLQ 531
Query: 667 SRILSLESQLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPS--ALTHSMDLKQ 724
+ +L+ LED +E L +++ E+G I Q S L + +DL +
Sbjct: 532 QELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTK 591
Query: 725 PSELEPLLPSSDSKLNKPLSPQKETANSQQT 755
S L + D+ LN ++E ++T
Sbjct: 592 DS----LKETKDALLNVEGELEQERQQHEET 618
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 45.4 bits (106), Expect = 2e-04
Identities = 57/297 (19%), Positives = 125/297 (42%), Gaps = 34/297 (11%)
Query: 415 REAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASIL---EGENRILRSRLAQQE 471
RE EE+ E + RR + M E +RRQ ++ E + R L ++ +QE
Sbjct: 392 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 451
Query: 472 EEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQ 531
+ Q + + + + ++K E M + ++++ Q E IR+ + EK + +
Sbjct: 452 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE-QEEKIREQE-EKMWRQEEKIHE 509
Query: 532 PQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTG 591
+ ++ + + ++M EE +R QE++ + E++ E + R + + RQ+ K +
Sbjct: 510 QEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHD- 568
Query: 592 FPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALPDLLSG 651
E E + + K+R + +K R Q+ I Q++ +
Sbjct: 569 --------------QEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE- 613
Query: 652 TSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQEKGFRHPSNSI 708
K+ + ++ E ++++ + R+++ +++EQEK R I
Sbjct: 614 ---------KMGEQEEKMCEQEEKMQEQEEKMRRQEE----KIREQEKKIREQEEKI 657
Score = 41.2 bits (95), Expect = 0.004
Identities = 47/228 (20%), Positives = 108/228 (47%), Gaps = 27/228 (11%)
Query: 356 ALSFQLLSSERPENFLTPNNSKALPTLDPKILDKKLRTIQESWSKDTVSSTMDLSTSTPR 415
ALS +L + + L N+K L +KL+ + ES + + +L R
Sbjct: 265 ALSLELYRNTITDEELKEKNAK---------LQEKLQLV-ESEKSEIQLNVKELKRKLER 314
Query: 416 EAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEE- 474
+ L+P+ E ++ + +Q + S + QA + E E L +RL QQ+EE+
Sbjct: 315 A---KLLLPQQQLQAEADHLGKELQSV-----SAKLQAQVEENE---LWNRLNQQQEEKM 363
Query: 475 --GQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDRE--KELLLLYQAQ 530
+ K E + + +++ + + + + ++ Q E++ + + + ++ ++++ +
Sbjct: 364 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 423
Query: 531 QPQAALLKQYQGKLQKMKALEETVRHQEKVIEKME-RVLEDRLQDRSK 577
+ + K +K++ LEE + QEK+ E+ E R E++++++ K
Sbjct: 424 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 471
Score = 38.1 bits (87), Expect = 0.030
Identities = 39/199 (19%), Positives = 84/199 (42%), Gaps = 11/199 (5%)
Query: 388 DKKLRTIQESWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAMQKMAEDIL 447
++K+R +E W + + ++ E+ E HD E R +K+
Sbjct: 529 EEKIREQEEIWRQK--EKIHEQEEKIRKQEEKMWRQEEKMHDQE-EKIREQEEKVWRQEE 585
Query: 448 SLRRQAS-ILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRV 506
+R Q I E E +I QE+EE G+ E ++K+ E M++ +++
Sbjct: 586 KIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM--CEQEEKMQEQEEKMRRQEEKI 643
Query: 507 QHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMER 566
+ + ++ RE+E + Q + Q K ++ + + + E+ +EK+ + E+
Sbjct: 644 REQEKKI-----REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 698
Query: 567 VLEDRLQDRSKPPPLNRQQ 585
+ E ++ R + + Q
Sbjct: 699 MWEQEVRLRQQEEKMQEHQ 717
Score = 37.4 bits (85), Expect = 0.052
Identities = 55/264 (20%), Positives = 114/264 (43%), Gaps = 21/264 (7%)
Query: 447 LSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTV-SMKQKLLLSELDMKKLRDR 505
L+ R A LE + R+ + +E +E K E V S K ++ L+ ++K+ +R
Sbjct: 259 LTKERDALSLE----LYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 314
Query: 506 V------QHLQNELIRKNDREKELLLLYQAQQPQAALLKQY-QGKLQKMKALEETVRH-Q 557
Q LQ E + + QAQ + L + Q + +KM EE ++ +
Sbjct: 315 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 374
Query: 558 EKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVL 617
EK+ E+ E++ E + R + + RQ+ + + + E + + ++
Sbjct: 375 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ-EEMM 433
Query: 618 LAENAKLRTELDKNRHQQAPIILQQQAL--PDLLSGTSDKFNLLAKLEHAQSRILSLESQ 675
+ K+R EL++ H+Q I Q++ + + + AK+ + +I E +
Sbjct: 434 WEKEEKIR-ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 492
Query: 676 LEDSARRWGREKQDLATRLQEQEK 699
+ + + R+++ ++ EQEK
Sbjct: 493 IREQEEKMWRQEE----KIHEQEK 512
Score = 36.6 bits (83), Expect = 0.088
Identities = 36/194 (18%), Positives = 89/194 (45%), Gaps = 18/194 (9%)
Query: 388 DKKLRTIQES-WSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAMQKMAEDI 446
++K+R +E W ++ + + E+E + + E R +K+ E
Sbjct: 490 EEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQE 549
Query: 447 LSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRV 506
+R+Q E ++ R ++EE K E + V +++ + + + K+R++
Sbjct: 550 EKIRKQ------EEKMWRQEEKMHDQEE---KIREQEEKVWRQEEKIREQEE--KIREQE 598
Query: 507 QHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKME- 565
+ ++ + ++E+++ + ++ ++ Q + +KM+ EE +R QEK I + E
Sbjct: 599 EKIREQEEMTQEQEEKM---GEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEE 655
Query: 566 --RVLEDRLQDRSK 577
R E+ +Q++ +
Sbjct: 656 KIREQEEMMQEQEE 669
Score = 33.1 bits (74), Expect = 0.98
Identities = 45/211 (21%), Positives = 88/211 (41%), Gaps = 38/211 (18%)
Query: 415 REAEEEPLVPEMSHDTEMNNYRRAM------QKMAEDILSLRRQASILEGENRILRSRLA 468
R+ EE+ E + E +R+ +K+ E + RQ + + +I
Sbjct: 460 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKR 519
Query: 469 QQEEE--EGQGKASEAQNTVSMKQKLLLSELDMKKLRDRV------QHLQNELIRKND-- 518
Q++EE + K E + K+K+ E ++K +++ H Q E IR+ +
Sbjct: 520 QEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEK 579
Query: 519 ---------------REKELLLLYQAQ--QPQAALLKQYQGKL----QKMKALEETVRHQ 557
RE+E + Q + Q Q + + + K+ +KM+ EE +R Q
Sbjct: 580 VWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQ 639
Query: 558 E-KVIEKMERVLEDRLQDRSKPPPLNRQQGK 587
E K+ E+ +++ E + R + + Q+ K
Sbjct: 640 EEKIREQEKKIREQEEKIREQEEMMQEQEEK 670
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 45.1 bits (105), Expect = 2e-04
Identities = 75/332 (22%), Positives = 140/332 (42%), Gaps = 48/332 (14%)
Query: 440 QKMAEDILSLRRQASILEGENRILRSRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDM 499
Q+ E L+ + S+LE + + L +L EEE + S+ + T +Q LL +
Sbjct: 1023 QRAQEHSSRLQAEKSVLEIQGQELHRKLEVLEEEVRAARQSQ-EETRGQQQALLRDHKAL 1081
Query: 500 KKLRDRVQ-HLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQE 558
+L+ R + L+ L+R D + + L A ++ QG+ ++++A +V QE
Sbjct: 1082 AQLQRRQEAELEGLLVRHRDLKANMRALELAH-------RELQGRHEQLQAQRASVEAQE 1134
Query: 559 -KVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVL 617
++ + ER+++D + R L R Q + +L+ G L
Sbjct: 1135 VALLAERERLMQDGHRQRGLEEELRRLQSEHDRAQMLLAELSRERGE------------L 1182
Query: 618 LAENAKLRTELDKNRHQQAPIILQQQALPDL-----LSG--TSDKFNLLAKLEHAQSRIL 670
E +LR L + ++A + +Q Q L + LS + + LL +L AQ
Sbjct: 1183 QGERGELRGRLARLELERAQLEMQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQE--- 1239
Query: 671 SLESQLEDSARRWGREKQDLATR-------LQEQEKGFRHPSNSIIIEQPSALTHSMDLK 723
QL + RE ++L R L +++ + N++ E+ + MD
Sbjct: 1240 EENRQLLAEVQALSRENRELLERSLESRDHLHREQREYLDQLNALRREKQKLVEKIMD-- 1297
Query: 724 QPSELEPL-LPSSD------SKLNKPLSPQKE 748
Q LEP+ LP + K+ + + P++E
Sbjct: 1298 QYRVLEPVPLPRTKKGSWLADKVKRLMRPRRE 1329
Score = 40.8 bits (94), Expect = 0.005
Identities = 63/277 (22%), Positives = 112/277 (40%), Gaps = 27/277 (9%)
Query: 444 EDILSLRRQASILEGENRILR---SRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMK 500
E ++ L+ +A LE E LR + L ++ E Q ++ + +++ + +
Sbjct: 936 EALMELKTRALQLEEELFQLRQGPAGLGPKKRAEPQLVETQNVRLIEVERSNAMLVAEKA 995
Query: 501 KLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQ--------KMKALEE 552
L+ ++QHL+ +L R +ELLL Q Q ++ L+ + L+ K++ LEE
Sbjct: 996 ALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSVLEIQGQELHRKLEVLEE 1055
Query: 553 TVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPM-----------LSASGLP 601
VR + E+ + L+D L R+Q G + L +
Sbjct: 1056 EVRAARQSQEETRGQQQALLRDHKALAQLQRRQEAELEGLLVRHRDLKANMRALELAHRE 1115
Query: 602 LGSMGENLPVELYSVLLAENAKL--RTELDKNRHQQAPIILQQQALPDLLSGTSDKFNLL 659
L E L + SV E A L R L ++ H+Q + ++ L L S LL
Sbjct: 1116 LQGRHEQLQAQRASVEAQEVALLAERERLMQDGHRQRGL---EEELRRLQSEHDRAQMLL 1172
Query: 660 AKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQE 696
A+L + + +L R E+ L + Q+
Sbjct: 1173 AELSRERGELQGERGELRGRLARLELERAQLEMQSQQ 1209
Score = 35.0 bits (79), Expect = 0.26
Identities = 59/257 (22%), Positives = 104/257 (40%), Gaps = 50/257 (19%)
Query: 414 PREAEEEPLVPEMSH-DTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEE 472
P E L ++++ ++ R+ +++ AE +L + + LE E R LR + +
Sbjct: 248 PAEGPSHHLALQLANAKAQLRRLRQELEEKAELLLDSQAEVQGLEAEIRRLRQ---EAQA 304
Query: 473 EEGQGKASE-----AQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLY 527
GQ K +E A+ +L + ++++ R+R+Q + K+ E+E +L
Sbjct: 305 LSGQAKRAELYREEAEALRERAGRLPRLQEELRRCRERLQAAE---AYKSQLEEERVLSG 361
Query: 528 QAQQPQAALLKQYQGKLQKMKALEET--------------------VRHQEKVIEKMERV 567
+ +A L +Q + ++ L ET +RHQ + +
Sbjct: 362 VLEASKALLEEQLEAARERCARLHETQRENLLLRTRLGEAHAELDSLRHQVDQLAEENVE 421
Query: 568 LEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTE 627
LE LQ +PPP G P PL +L E V AE +LRT
Sbjct: 422 LELELQRSLEPPP-----GSP---------GEAPLAGAAPSLQDE---VREAEAGRLRTL 464
Query: 628 LDKNRHQQAPI-ILQQQ 643
+NR + + +LQ Q
Sbjct: 465 ERENRELRGLLQVLQGQ 481
Score = 33.1 bits (74), Expect = 0.98
Identities = 50/175 (28%), Positives = 80/175 (45%), Gaps = 27/175 (15%)
Query: 415 REAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILRSRLAQQEEEE 474
R EEE + HD RA +AE L R+ L+GE LR RLA+ E E
Sbjct: 1152 RGLEEELRRLQSEHD-------RAQMLLAE----LSRERGELQGERGELRGRLARLELER 1200
Query: 475 GQGKASEAQNTVSMKQKLLLSELDMK---KLRDRVQHLQNELIRKNDREKELL------L 525
Q ++Q Q+L LS + +L +++ Q E R+ E + L L
Sbjct: 1201 AQ-LEMQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQALSRENREL 1259
Query: 526 LYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKM---ERVLEDRLQDRSK 577
L ++ + + L ++ + L ++ AL R ++K++EK+ RVLE R+K
Sbjct: 1260 LERSLESRDHLHREQREYLDQLNALR---REKQKLVEKIMDQYRVLEPVPLPRTK 1311
>gi|55749678 ninein-like [Homo sapiens]
Length = 1382
Score = 44.7 bits (104), Expect = 3e-04
Identities = 49/187 (26%), Positives = 85/187 (45%), Gaps = 32/187 (17%)
Query: 418 EEEPLVPEMSHDTEMN-NYRRAMQKMAEDILSLRRQASILEGEN---RILRSRLAQQEEE 473
++E EM N NY+ + ++ +L L ++AS + +N R+ L Q EE
Sbjct: 1127 DKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEE 1186
Query: 474 ---EGQGKASEAQ---------NTVSMKQKLLLSELD--MKKLRDRVQ------------ 507
GQ ++ + Q N +L SEL +++ +D+VQ
Sbjct: 1187 VVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQ 1246
Query: 508 HLQNELIRKNDREKEL--LLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKME 565
HLQ + DR EL LL Q +Q + L Q + +++KA EE V E +++ ME
Sbjct: 1247 HLQEVRLVPQDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNME 1306
Query: 566 RVLEDRL 572
+L++++
Sbjct: 1307 MLLQEKV 1313
Score = 40.8 bits (94), Expect = 0.005
Identities = 100/486 (20%), Positives = 191/486 (39%), Gaps = 111/486 (22%)
Query: 281 FSEDTALVLEYYSSTSMKGSQPWTLNQPLGISVLPLKSRLYQKMLTGKGLDGLHVERLPI 340
FS + AL+LE SST +K S+ W+ Q +P +S G L
Sbjct: 263 FSHEPALLLE--SSTRVKPSKAWSHYQ------VPEES----------GCHTTTTSSLVS 304
Query: 341 MDTSLKTIN--DEAPTVALSFQLLSSERPENFLTPNNSKALPTLDPKILDKKLRTIQESW 398
+ +SL+ + D+ A Q+L+ E N + L +LD + D+K+ ++ +W
Sbjct: 305 LCSSLRLFSSIDDGSGFAFPDQVLAMWTQEGI--QNGREILQSLDFSV-DEKVNLLELTW 361
Query: 399 SKDTVSSTMDLSTSTP-----------REAEEEPLVPE---------------MSHDTEM 432
+ D T+D + ++ + E L E + EM
Sbjct: 362 ALDNELMTVDSAVQQAALACYHQELSYQQGQVEQLARERDKARQDLERAEKRNLEFVKEM 421
Query: 433 NNYRRAMQKMAEDILS-----LRRQASILEGENRILRSRLAQQ--------EEEEGQGKA 479
++ ++++ E + R + S+L E R +Q E + G+ +A
Sbjct: 422 DDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAERELFWEQAHRQRAALEWDVGRLQA 481
Query: 480 SEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNEL----------------IRKNDREKEL 523
EA +++KL L+ + +L+ + + +L + K+ E +
Sbjct: 482 EEA----GLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKDLEFVLKDKLEPQS 537
Query: 524 LLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNR 583
L ++ AA+LK+Y+ K + ++ + ++ + +E + L S P R
Sbjct: 538 AELLAQEERFAAVLKEYELKCRDLQDRNDELQAE---LEGLWARLPKNRHSPSWSPDGRR 594
Query: 584 QQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAK-----LRTELD--------- 629
+Q P L +G+ +G + PV + + L+ E K LRT+L+
Sbjct: 595 RQ------LPGLGPAGISF--LGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYERE 646
Query: 630 ----KNRHQQAPIILQQQALPDLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGR 685
K ++ ++Q ++ K +L E +Q I L+ QL+D+AR
Sbjct: 647 IAALKRNFEKERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGPEP 706
Query: 686 EKQDLA 691
E+ LA
Sbjct: 707 EQMGLA 712
Score = 34.3 bits (77), Expect = 0.44
Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 17/133 (12%)
Query: 473 EEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNEL-IRKNDREKELLLLYQAQQ 531
EEG+ K + + M+ KLL L D V+ L+ + +R+NDR L +
Sbjct: 1043 EEGETKIALEREKDDMETKLL-------HLEDVVRALEKHVDLRENDR-----LEFHRLS 1090
Query: 532 PQAALLKQYQGKL-QKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYT 590
+ LLK G++ Q+++A E T Q K IE +++ D+ + S+ LNRQ
Sbjct: 1091 EENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKK---DKEKACSEMEVLNRQNQNYKD 1147
Query: 591 GFPMLSASGLPLG 603
L+ L LG
Sbjct: 1148 QLSQLNVRVLQLG 1160
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,149,637
Number of Sequences: 37866
Number of extensions: 1399339
Number of successful extensions: 6449
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 572
Number of HSP's that attempted gapping in prelim test: 5191
Number of HSP's gapped (non-prelim): 1574
length of query: 755
length of database: 18,247,518
effective HSP length: 110
effective length of query: 645
effective length of database: 14,082,258
effective search space: 9083056410
effective search space used: 9083056410
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.