Guide to the Human Genome
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Search of human proteins with 239741731

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239741731 PREDICTED: hypothetical protein XP_002342307 [Homo
sapiens]
         (316 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239741731 PREDICTED: hypothetical protein XP_002342307 [Homo ...   672   0.0  
gi|239755710 PREDICTED: hypothetical protein [Homo sapiens]           487   e-138
gi|239757987 PREDICTED: hypothetical protein [Homo sapiens]           201   5e-52
gi|239746104 PREDICTED: hypothetical protein XP_002344198 [Homo ...    96   3e-20
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    65   6e-11
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    62   7e-10
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 60   2e-09
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    58   1e-08
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          58   1e-08
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          58   1e-08
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          58   1e-08
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     57   3e-08
gi|169215850 PREDICTED: transmembrane protein 46-like [Homo sapi...    56   4e-08
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       55   6e-08
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                55   1e-07
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    54   2e-07
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    54   2e-07
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 54   2e-07
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         54   2e-07
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    54   2e-07
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     53   3e-07
gi|169162152 PREDICTED: hypothetical protein [Homo sapiens]            53   4e-07
gi|169161145 PREDICTED: hypothetical protein [Homo sapiens]            53   4e-07
gi|110431370 espin [Homo sapiens]                                      52   5e-07
gi|40353727 synaptopodin isoform A [Homo sapiens]                      52   7e-07
gi|150170670 piccolo isoform 2 [Homo sapiens]                          52   7e-07
gi|150378539 piccolo isoform 1 [Homo sapiens]                          52   7e-07
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      52   9e-07
gi|134244285 Notch homolog 3 [Homo sapiens]                            52   9e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   9e-07

>gi|239741731 PREDICTED: hypothetical protein XP_002342307 [Homo
           sapiens]
          Length = 316

 Score =  672 bits (1733), Expect = 0.0
 Identities = 316/316 (100%), Positives = 316/316 (100%)

Query: 1   MEEFREGATFLTPYKVLATCQAPFPYIVSVQLPTLDKQETLVAEERRGWKQRGRNGAPGT 60
           MEEFREGATFLTPYKVLATCQAPFPYIVSVQLPTLDKQETLVAEERRGWKQRGRNGAPGT
Sbjct: 1   MEEFREGATFLTPYKVLATCQAPFPYIVSVQLPTLDKQETLVAEERRGWKQRGRNGAPGT 60

Query: 61  QRGVREVGSPTRDQEIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQSPGPCAPQALA 120
           QRGVREVGSPTRDQEIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQSPGPCAPQALA
Sbjct: 61  QRGVREVGSPTRDQEIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQSPGPCAPQALA 120

Query: 121 SLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTV 180
           SLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTV
Sbjct: 121 SLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTV 180

Query: 181 PGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPP 240
           PGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPP
Sbjct: 181 PGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPP 240

Query: 241 PAPPGPNAAAHPPLRPPRARLQDPVDPERCPGGPSRGPGHGTHAHSELPTCTRLPSVVFR 300
           PAPPGPNAAAHPPLRPPRARLQDPVDPERCPGGPSRGPGHGTHAHSELPTCTRLPSVVFR
Sbjct: 241 PAPPGPNAAAHPPLRPPRARLQDPVDPERCPGGPSRGPGHGTHAHSELPTCTRLPSVVFR 300

Query: 301 ASGRPYPCFLLCRPSS 316
           ASGRPYPCFLLCRPSS
Sbjct: 301 ASGRPYPCFLLCRPSS 316


>gi|239755710 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 402

 Score =  487 bits (1254), Expect = e-138
 Identities = 231/243 (95%), Positives = 236/243 (97%)

Query: 1   MEEFREGATFLTPYKVLATCQAPFPYIVSVQLPTLDKQETLVAEERRGWKQRGRNGAPGT 60
           MEEFREGATFLTPYKVLATCQAPFPY+VSVQLPTLDKQETLVAEE+RGWKQRGRNGAPGT
Sbjct: 1   MEEFREGATFLTPYKVLATCQAPFPYLVSVQLPTLDKQETLVAEEKRGWKQRGRNGAPGT 60

Query: 61  QRGVREVGSPTRDQEIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQSPGPCAPQALA 120
           QRGVREVGSPTRDQE+RAGSSCGRAARGFPEPGRGGKTQ+WGGGTGTPQSPGPCAPQALA
Sbjct: 61  QRGVREVGSPTRDQELRAGSSCGRAARGFPEPGRGGKTQKWGGGTGTPQSPGPCAPQALA 120

Query: 121 SLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTV 180
           SLLGPGKAGCR RLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTV
Sbjct: 121 SLLGPGKAGCRTRLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTV 180

Query: 181 PGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPP 240
           PGLPPASLQPLR+PY APPGPHDPTSRGPGRLLT EPPSRKLPPPLP CRSRWVLAPPP 
Sbjct: 181 PGLPPASLQPLRLPYLAPPGPHDPTSRGPGRLLTCEPPSRKLPPPLPPCRSRWVLAPPPT 240

Query: 241 PAP 243
             P
Sbjct: 241 VRP 243


>gi|239757987 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 445

 Score =  201 bits (512), Expect = 5e-52
 Identities = 129/293 (44%), Positives = 144/293 (49%), Gaps = 57/293 (19%)

Query: 1   MEEFREGATFLTPYKVLATCQAPFPYIVSVQLPTLDKQETLVAEERRGWKQRGRNG---- 56
           MEEF EGATFLTPYKVLATCQAPFPYIVS QLPTLDKQETLVAEE+RGWKQRGRNG    
Sbjct: 1   MEEFTEGATFLTPYKVLATCQAPFPYIVSAQLPTLDKQETLVAEEKRGWKQRGRNGENAD 60

Query: 57  ---------------------------------------APGTQRGVREVGSPTRDQEIR 77
                                                   PG  +  +  G P       
Sbjct: 61  TARLFGTTVYTFEVLGALPPDRSPTPRSRVSPGVTGLAVGPGNPKRCQRSGVPYEGPGAP 120

Query: 78  AGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGG 137
            G    ++    P    G +     G    P  PG   P +L     P +AG + ++QG 
Sbjct: 121 GGQQLRKSRARLPRTRPGREDAAVRGRNRDPAEPGSLRPTSLGF---PARAG-QGQVQGA 176

Query: 138 SSG----ASPRRLPGGRGPAAAFAVEPGTGQRPRNT--SLAQASRSGTVPGLPPASLQPL 191
           + G      P+  PG  GP+    V  G G R       L         PG PPA L P 
Sbjct: 177 APGRRLRGEPKTPPGRSGPSG--GVRSGAGHRAATAEHQLGAGFSVRNGPG-PPARLPPA 233

Query: 192 RV-PYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAP 243
              P   P  PH+PTSRGPGRLLT EPPSRKLPPPLPLCRSRWVLAPPP   P
Sbjct: 234 PPGPPLRPARPHNPTSRGPGRLLTCEPPSRKLPPPLPLCRSRWVLAPPPTVRP 286



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 84/297 (28%), Positives = 106/297 (35%), Gaps = 53/297 (17%)

Query: 52  RGRNGAPGTQRGVR--EVGSPTRDQEIRA-GSSCGRAARGFPE--PGRGGKTQEWGGGTG 106
           RGRN  P     +R   +G P R  + +  G++ GR  RG P+  PGR G +     G G
Sbjct: 145 RGRNRDPAEPGSLRPTSLGFPARAGQGQVQGAAPGRRLRGEPKTPPGRSGPSGGVRSGAG 204

Query: 107 TPQSPGPCAPQALASLL-GPGKAGCRARLQGGSSGASPRRL----PGGRGPAAAFAVEPG 161
              +       A  S+  GPG     ARL     G   R      P  RGP      EP 
Sbjct: 205 HRAATAEHQLGAGFSVRNGPGPP---ARLPPAPPGPPLRPARPHNPTSRGPGRLLTCEPP 261

Query: 162 TGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPP----------GPHDPTSR---- 207
           + + P    L    RS  V   PP     LRV    PP          G   P++R    
Sbjct: 262 SRKLPPPLPLC---RSRWVLAPPPTVRPRLRV--LTPPFTLLCALPERGSRTPSTRSAVL 316

Query: 208 -----GPGRLLTREPPSRKLPPPLPLCRSRWVLA----------PPPP---PAPPGPNAA 249
                G G  LT  P SR+     PL   R              P PP   P+ P P A 
Sbjct: 317 VDRVAGLGTELTLTPSSRRAHGSHPLSSERQAAPTRAFCSADPLPRPPSFVPSLPSPQAQ 376

Query: 250 AHPPLRPP--RARLQDPVDPERCPG-GPSRGPGHGTHAHSELPTCTRLPSVVFRASG 303
                +P   RA L       R P  GP   P    ++ +  P    LP +VF + G
Sbjct: 377 GQAVRQPRLLRAALALGAPRGRTPSPGPGPAPALQPYSLTRFPASLSLPDLVFTSVG 433


>gi|239746104 PREDICTED: hypothetical protein XP_002344198 [Homo
           sapiens]
          Length = 398

 Score = 96.3 bits (238), Expect = 3e-20
 Identities = 72/196 (36%), Positives = 87/196 (44%), Gaps = 20/196 (10%)

Query: 58  PGTQRGVREVGSPTRDQEIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQSPGPCAPQ 117
           PG     +  G P        G    ++    P   +G +    G     P  PG   P 
Sbjct: 54  PGNPTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQGREDAGVGRRNRDPAEPGSLRPT 113

Query: 118 ALASLLGPGKAGCRARLQGGSSG----ASPRRLPGGRGPAAAFAVEPGTGQRP----RNT 169
           +L     P +AG + R+QG + G      P+  PG  GP+    V  G G R        
Sbjct: 114 SLGF---PARAG-QGRVQGAAPGRKLRGEPKTPPGRSGPSGG--VRSGAGHRAAAAEHQL 167

Query: 170 SLAQASRSGTVPG--LPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLP 227
               + R+G  P   LPPA   PL  P   PP P+ P  R P    T EPPSRKLPPPLP
Sbjct: 168 GAGFSVRNGPGPPARLPPAPPGPLLRPA-RPPRPYFPRPRTPP---TCEPPSRKLPPPLP 223

Query: 228 LCRSRWVLAPPPPPAP 243
           LCRSRWVLAPPPP  P
Sbjct: 224 LCRSRWVLAPPPPVRP 239



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 56/199 (28%), Positives = 69/199 (34%), Gaps = 36/199 (18%)

Query: 103 GGTGTPQSPGP---CAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVE 159
           G     +SP P    +P   +  +GPG      R Q           PGG+    + A  
Sbjct: 29  GALPPDRSPTPRSRVSPGVTSLAVGPGNP---TRCQRSGVPYEGPGAPGGQQLRKSRARL 85

Query: 160 PGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPS 219
           P T Q   +  + + +R    PG    SL+P  + + A  G        PGR L  EP  
Sbjct: 86  PRTRQGREDAGVGRRNRDPAEPG----SLRPTSLGFPARAGQGRVQGAAPGRKLRGEP-- 139

Query: 220 RKLPP----PLPLCRSRW----------------VLAPPPPPA--PPGPNAAAHPPLRPP 257
            K PP    P    RS                  V   P PPA  PP P      P RPP
Sbjct: 140 -KTPPGRSGPSGGVRSGAGHRAAAAEHQLGAGFSVRNGPGPPARLPPAPPGPLLRPARPP 198

Query: 258 RARLQDPVDPERCPGGPSR 276
           R     P  P  C   PSR
Sbjct: 199 RPYFPRPRTPPTCE-PPSR 216


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 65.5 bits (158), Expect = 6e-11
 Identities = 70/257 (27%), Positives = 87/257 (33%), Gaps = 47/257 (18%)

Query: 57  APGTQRGVREVGSPTRDQEIRAGSSCGRAARG-----------FPEPGRGGKTQEWGGGT 105
           AP T   VR   +      + +GS  G A  G            PEP   G+ +  GGG 
Sbjct: 44  APRTPE-VRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGG- 101

Query: 106 GTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQR 165
             PQ PGP +P+      GP     + R     S  S   +P     AA     P    +
Sbjct: 102 --PQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAK 159

Query: 166 PRNTSLAQASRSGTVPGLPPASLQPLRVPYFAP-PGPHDPTSRG---------------- 208
           P   + A A+R+G  PG  P            P PGP  P   G                
Sbjct: 160 PAGPA-ALAARAGPGPGPGPGP---------GPGPGPGKPAGPGAAQTLNGSAALLNSHH 209

Query: 209 ---PGRLLTREPPSRKLPPPLPLCRSRWVLAPP--PPPAPPGPNAAAHPPLRPPRARLQD 263
              P   L    P+  LP P P      +  PP     APP P A + P    P A    
Sbjct: 210 AAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAA 269

Query: 264 PVDPERCPGGPSRGPGH 280
           P  P   P   +R PGH
Sbjct: 270 PPPPPPAPATLARPPGH 286



 Score = 35.4 bits (80), Expect = 0.067
 Identities = 49/173 (28%), Positives = 63/173 (36%), Gaps = 26/173 (15%)

Query: 102 GGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPG 161
           G  T  P  P P A Q   S    G A   A   GG +G S +  PG    A A  V+  
Sbjct: 289 GPPTAAPAVPPPAAAQNGGSA---GAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAE 345

Query: 162 TGQR------PRNTSLAQASRSGTV------PGLPPASLQPLRVPYFAPPGPHDPTSRGP 209
           + +R      P   +LA +  + T       P +  A   P  VP   PP P  PT    
Sbjct: 346 SPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP---PPAPGTPTGLPK 402

Query: 210 G------RLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRP 256
           G      + L+R P +        L  +  VLAP  P  P  P    +  L P
Sbjct: 403 GAAGAVTQSLSRTPTATTSGIRATLTPT--VLAPRLPQPPQNPTNIQNFQLPP 453



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 52/194 (26%), Positives = 63/194 (32%), Gaps = 26/194 (13%)

Query: 78  AGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGG 137
           AG   G    G P PG        G    +P+     AP A  +L   G A   A +  G
Sbjct: 319 AGGPAG--VSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIG 376

Query: 138 --------SSGASPRRLPG---GRGPAAAFAVEPGTGQRP-RNTSLAQASRSGTV--PGL 183
                   S  A P   PG   G    AA AV     + P   TS  +A+ + TV  P L
Sbjct: 377 PTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRL 436

Query: 184 PPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAP 243
           P     P  +  F  P         PG +L R    + L  P          A   P   
Sbjct: 437 PQPPQNPTNIQNFQLP---------PGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTT 487

Query: 244 PGPNAAAHPPLRPP 257
             P  A  P   PP
Sbjct: 488 MAPRPAT-PTSAPP 500


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 63/210 (30%), Positives = 73/210 (34%), Gaps = 20/210 (9%)

Query: 75  EIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARL 134
           E +AG   G +   FP+ GRG + +  G   G  + PGP  P         G+   R  L
Sbjct: 183 EGKAGPPGGSSRAAFPQGGRG-RGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPL 241

Query: 135 QGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTVP--GLPPASLQPLR 192
                   P   P G+      A  P  G RP    L      G  P   LPP    P  
Sbjct: 242 GPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPP-- 299

Query: 193 VPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPP----PPPAPPGPNA 248
           VP + PP    P  +GP       PP    PP     R    L PP    PPP  PGP  
Sbjct: 300 VPGYGPPPGPPPPQQGP------PPPPGPFPP-----RPPGPLGPPLTLAPPPHLPGPPP 348

Query: 249 AAHPPLRPPRARLQDPVDPERCPGGPSRGP 278
            A PP          P      P   SRGP
Sbjct: 349 GAPPPAPHVNPAFFPPPTNSGMPTSDSRGP 378



 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 68/214 (31%), Positives = 75/214 (35%), Gaps = 44/214 (20%)

Query: 125 PGKAGCRARLQGGSS-GASPRRLPGGR---GPAAAFAVEPG--TGQRPRNTSLAQASRSG 178
           PG +   A  QGG   G  P  +PGG    GPA      P    GQ P    L      G
Sbjct: 189 PGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPG 248

Query: 179 TVPGLPPASLQPLRVPYFAPPGPHD---PTSRGPGRLLTREPPSRKLPPPLPLCRSRWVL 235
             PG PP   Q L  P   PP   D   P    PG+    +PP   LPP  P        
Sbjct: 249 P-PGPPPPG-QVLPPPLAGPPNRGDRPPPPVLFPGQPFG-QPPLGPLPPGPP-------- 297

Query: 236 APP-----PPPAPPGPNAAAHP-----------PLRPPRARLQDPVDPERCPGGPSRGPG 279
            PP     PPP PP P     P           PL PP      P  P   PG P   P 
Sbjct: 298 -PPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAP- 355

Query: 280 HGTHAHSELPTCTRLPSVVFRAS------GRPYP 307
           H   A    PT + +P+   R        GRP P
Sbjct: 356 HVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 48/169 (28%), Positives = 54/169 (31%), Gaps = 36/169 (21%)

Query: 113 PCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTSLA 172
           PC  Q L+      +   ++    G   A P   PGG   AA      G G+ P      
Sbjct: 158 PCNKQFLSQFEMQSRKTTQSGQMSGEGKAGP---PGGSSRAAFPQGGRGRGRFP------ 208

Query: 173 QASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSR 232
                G VPG                PGP  P    P     + PP   L PP       
Sbjct: 209 -----GAVPGGDRF------------PGPAGPGGPPPPFPAGQTPPRPPLGPP------- 244

Query: 233 WVLAPPPPPAPPGPNAAAHPPLRPPRARLQDPVDPERCPGGPSRGPGHG 281
               PP PP PP P     PPL  P  R   P  P   PG P   P  G
Sbjct: 245 ---GPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG 290



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 35/122 (28%), Positives = 41/122 (33%), Gaps = 14/122 (11%)

Query: 90  PEPGRGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGG 149
           P PG G          G P  PGP  P+       PG  G    L      A P  LPG 
Sbjct: 299 PVPGYGPPPGPPPPQQGPPPPPGPFPPRP------PGPLGPPLTL------APPPHLPGP 346

Query: 150 R--GPAAAFAVEPGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSR 207
               P  A  V P     P N+ +  +   G  P  P     P     + PPG    T+R
Sbjct: 347 PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTAR 406

Query: 208 GP 209
            P
Sbjct: 407 TP 408


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 73/219 (33%), Positives = 82/219 (37%), Gaps = 30/219 (13%)

Query: 52  RGRNGAPGTQRGVREVGSPTRDQEIR-AGSSCGRAARGFPEPGRGGKTQEWG--GGTGTP 108
           RG  G PG +     VG P     +  AG    +  RG  E G  G     G  G +G P
Sbjct: 718 RGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRG--EQGLTGMPGIRGPPGPSGDP 775

Query: 109 QSPGPCAPQALASLLG-PGKAGCRARLQGG-----SSGASPRRLPGGRGPAAAFAVEPGT 162
             PG   PQ    L G PG+ G +           S G+S   +PG  GP  A    PG 
Sbjct: 776 GKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMG-PPGP 834

Query: 163 GQRPRNTSLAQASRSGTVPGL--PPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSR 220
              P     A       V  L  PP    P       PPGP  P   GP     R PP  
Sbjct: 835 PGAPGPAGPAGLPGHQEVLNLQGPPGPPGPR-----GPPGPSIPGPPGP-----RGPPGE 884

Query: 221 KLP-PPLP----LCRSRWVLAPPP-PPAPPGPNAAAHPP 253
            LP PP P    L  S   L+ PP PP PPGP     PP
Sbjct: 885 GLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPP 923



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 79/260 (30%), Positives = 96/260 (36%), Gaps = 45/260 (17%)

Query: 51  QRGRNGAPGTQRGVREVGSPTRDQEIRAGSSCGRAARGFPE-PGRGGKTQEWGGGTGTPQ 109
           QRGR G  G  RG  E G P   ++   G++      G P  PG  G      G +G+P 
Sbjct: 622 QRGREGPMGP-RG--EAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPK----GSSGSPG 674

Query: 110 SPGPCAPQALASLLG----PGKAGCRARL-----QGGSSGASPRRL---PGGRGPAAAFA 157
             GP  P  L  L G    PG  G +  +     +G      PR L   PG RG   A  
Sbjct: 675 PQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVG 734

Query: 158 VEPGT--GQRPRNTSLAQASRSGT----VPGL---PPASLQPLRVPYFAPPGPHD----- 203
            EPG      P      Q  R       +PG+   P  S  P +     P GP       
Sbjct: 735 -EPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTP 793

Query: 204 --PTSRG----PGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPP 257
             P  +G    PG+++T E  S    P  P       + PP PP  PGP   A  P    
Sbjct: 794 GRPGIKGEPGAPGKIVTSEGSSMLTVPGPP--GPPGAMGPPGPPGAPGPAGPAGLPGHQE 851

Query: 258 RARLQDPVDP--ERCPGGPS 275
              LQ P  P   R P GPS
Sbjct: 852 VLNLQGPPGPPGPRGPPGPS 871



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 69/245 (28%), Positives = 85/245 (34%), Gaps = 55/245 (22%)

Query: 52  RGRNGAPGTQRGVREVGSP----TRDQEIRAGSSCGRAARGFP----EPGRGGKTQEWGG 103
           RG  G PG +     +G P     + ++   G +     RG P    EPG  G      G
Sbjct: 688 RGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAM----G 743

Query: 104 GTGTPQSPGPCAPQALASLLG----PGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVE 159
             G     GP   Q L  + G    PG +G   +  G +    P+ LPG  G       E
Sbjct: 744 PAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGK-PGLTGPQGPQGLPGTPG-RPGIKGE 801

Query: 160 PGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPS 219
           PG    P     ++ S   TVPG               PPGP       PG +    PP 
Sbjct: 802 PGA---PGKIVTSEGSSMLTVPG---------------PPGP-------PGAMGPPGPPG 836

Query: 220 RKLPP-PLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPPRARLQDPVDPERCPG----GP 274
              P  P  L   + VL    PP PPGP         PP   +  P  P   PG    GP
Sbjct: 837 APGPAGPAGLPGHQEVLNLQGPPGPPGPRG-------PPGPSIPGPPGPRGPPGEGLPGP 889

Query: 275 SRGPG 279
              PG
Sbjct: 890 PGPPG 894



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 59/232 (25%), Positives = 72/232 (31%), Gaps = 49/232 (21%)

Query: 52   RGRNGAPGTQRGVREVGSPTRDQEIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQSP 111
            +G  G PGT       G P    +I             P PG  G      G  G P +P
Sbjct: 784  QGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGP-PGPPGAM----GPPGPPGAP 838

Query: 112  GPCAP------QALASLLGP-------GKAGCRARLQGGSSGASPRRLPGGRGPAAAFAV 158
            GP  P      Q + +L GP       G  G       G  G     LPG  GP  +F  
Sbjct: 839  GPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLS 898

Query: 159  E----------------PGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPH 202
                             P   Q P      Q  +   +PG   +      +    PPGP 
Sbjct: 899  NSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQG--LPGFSTSGSSSFGLNLQGPPGPP 956

Query: 203  DPTS----RG----PGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAPPGP 246
             P      +G    PG L     PS           + +V  PP PP PPGP
Sbjct: 957  GPQGPKGDKGDPGVPGALGIPSGPSEG-----GSSSTMYVSGPPGPPGPPGP 1003



 Score = 32.7 bits (73), Expect = 0.43
 Identities = 43/158 (27%), Positives = 54/158 (34%), Gaps = 32/158 (20%)

Query: 105  TGTPQSPGPCAPQALASLLGP----GKAGCRARLQGGSSG-----ASPRRLPGGRGPAAA 155
            +G P  PGP  P+      GP    G+ G       GSS        P   PG +GP   
Sbjct: 905  SGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGD 964

Query: 156  FAVE--PGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLL 213
                  PG    P   S   +S +  V G P             PPGP  P    PG + 
Sbjct: 965  KGDPGVPGALGIPSGPSEGGSSSTMYVSGPP------------GPPGPPGP----PGSIS 1008

Query: 214  T-----REPPSRKLPPPLPLCRSRWVLAPPPPPAPPGP 246
            +     ++  S  +           V  PP PP PPGP
Sbjct: 1009 SSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGP 1046



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 40/138 (28%), Positives = 48/138 (34%), Gaps = 25/138 (18%)

Query: 111  PGPCAPQALASLLGPGKAGCRARLQG--GSSGASPRRLPGGRGPAAAFAVEPGTGQRPRN 168
            PGP       SLL    A   +R+     SSG S   LPG  GP       PGT      
Sbjct: 1111 PGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIG-LPGPPGPPGL----PGTSYEELL 1165

Query: 169  TSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPL 228
            + L  +   G V                 PPGP  P    PG + +       L   L  
Sbjct: 1166 SLLRGSEFRGIV----------------GPPGPPGPPGI-PGNVWS-SISVEDLSSYLHT 1207

Query: 229  CRSRWVLAPPPPPAPPGP 246
                ++  PP PP PPGP
Sbjct: 1208 AGLSFIPGPPGPPGPPGP 1225


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 64/190 (33%), Positives = 75/190 (39%), Gaps = 22/190 (11%)

Query: 109 QSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRN 168
           Q P P  P A  + LGP         Q   S ASP   P  + PAAA    PG    P  
Sbjct: 731 QDPAPATPVAKGAGLGP---------QAPDSQASPA--PAPQIPAAAPLKGPGPSSSP-- 777

Query: 169 TSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLP- 227
            SL   +  G  P LP  S  P R P   PP      SR P        P  + PP LP 
Sbjct: 778 -SLPHQAPLGDSPHLP--SPHPTRPPS-RPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPG 833

Query: 228 LCRSRWVLAPPPPPAPPGPNAAAHPPLRPPRARLQDPVDPERCPGGPSRGPGHGTHA-HS 286
           +   +  L  PPP + P P A   PP  P R + Q P  P   P  P   P   + A  S
Sbjct: 834 IFVIQNQLGVPPPASNPAPTAPG-PPQPPLRPQSQPPEGP--LPPAPHLPPSSTSSAVAS 890

Query: 287 ELPTCTRLPS 296
              T +RLP+
Sbjct: 891 SSETSSRLPA 900



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 49/182 (26%), Positives = 64/182 (35%), Gaps = 27/182 (14%)

Query: 102  GGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPG 161
            GG  G+P      A  +L+S      A   + L     G  P R    R P   +     
Sbjct: 1251 GGAGGSPSVTWARASSSLSSSSSSSSAA--SSLDADEDGPMPSR---NRPPIKTYEARSR 1305

Query: 162  TGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRK 221
             G +     L     +G    +   +L P+  P   PP         P  L   EPP R 
Sbjct: 1306 IGLK-----LKIKQEAGLSKVVHNTALDPVHQP--PPP---------PATLKVAEPPPRP 1349

Query: 222  LPPPLPLCRSRWVLAPPPPPAPPGP--NAAAHPPLRPPRARLQD----PVDPERCPGGPS 275
             PPP P  +    +  PPP AP       A H P  P R   ++    P  PE  P G +
Sbjct: 1350 PPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRA 1409

Query: 276  RG 277
            RG
Sbjct: 1410 RG 1411



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 39/127 (30%), Positives = 49/127 (38%), Gaps = 22/127 (17%)

Query: 142 SPRRLPGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGP 201
           +P  LPG       F ++   G  P  ++ A  +     P L P S QP   P   PP P
Sbjct: 827 APPTLPG------IFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQS-QPPEGPL--PPAP 877

Query: 202 HDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAP---PGPNAAAH------- 251
           H P S     + +    S +LP P P   S + L  PP   P   P P    H       
Sbjct: 878 HLPPSSTSSAVASSSETSSRLPAPTP---SDFQLQFPPSQGPHKSPTPPPTLHLVPEPAA 934

Query: 252 PPLRPPR 258
           PP  PPR
Sbjct: 935 PPPPPPR 941



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 51/196 (26%), Positives = 64/196 (32%), Gaps = 41/196 (20%)

Query: 108 PQSPGPCA---PQALASLLGPGKAGCRARLQ-GGSSGASPRR----------LPGGRG-- 151
           PQ+P P A   PQA      PG A    ++  G    A+P            LP  R   
Sbjct: 648 PQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQ 707

Query: 152 -----------PAAAFAVEPGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPG 200
                      PA+     P   Q P   +   A  +G  P  P +   P   P      
Sbjct: 708 PLSAEGPHLSVPASVIVSAPPPAQDPAPATPV-AKGAGLGPQAPDSQASPAPAPQIPAAA 766

Query: 201 PHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAP----PPPPAPPGPNAAAHPPLRP 256
           P     +GPG        S  LP   PL  S  + +P    PP   P  P + + PP  P
Sbjct: 767 P----LKGPG-----PSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEP 817

Query: 257 PRARLQDPVDPERCPG 272
           P      P  P   PG
Sbjct: 818 PLHPCPPPQAPPTLPG 833



 Score = 35.8 bits (81), Expect = 0.051
 Identities = 36/148 (24%), Positives = 50/148 (33%), Gaps = 24/148 (16%)

Query: 166  PRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPP 225
            P +TS A AS S T   LP  +    ++ +    GPH   +  P   L  EP +   PPP
Sbjct: 881  PSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPP 940

Query: 226  --LPLCRSRWVLAPPP----------------------PPAPPGPNAAAHPPLRPPRARL 261
                +  + +   P P                       PA P  + +  P   P  + L
Sbjct: 941  RTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVL 1000

Query: 262  QDPVDPERCPGGPSRGPGHGTHAHSELP 289
                 P   P  PS  P     A + LP
Sbjct: 1001 VSGQAPSGTPTAPSHAPAPAPMAATGLP 1028



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 54/184 (29%), Positives = 60/184 (32%), Gaps = 45/184 (24%)

Query: 112 GPCAPQALASL-LGPGKAGC----------RARLQGGS--SGASPRRLPGGRGPAAAFAV 158
           GP  P  LAS  + P  AG              L G S   GA     P G       AV
Sbjct: 268 GPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAV 327

Query: 159 EPGTGQRP----------RNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRG 208
            PG G  P          R  +  Q   +G    LPP   Q    P FAP G        
Sbjct: 328 APGLGSSPLVPAPNVILHRTPTPIQPKPAGV---LPPKLYQLTPKP-FAPAGATLTIQGE 383

Query: 209 PGRLLTREPPSRKLPPPLPLCRS-----RWVLAPPPPPA--------PPGPNAAAHPPLR 255
           PG L    P   K P  L    +       VL+  P PA        PP     A PP +
Sbjct: 384 PGAL----PQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPP-Q 438

Query: 256 PPRA 259
           PP A
Sbjct: 439 PPGA 442



 Score = 29.3 bits (64), Expect = 4.8
 Identities = 26/107 (24%), Positives = 37/107 (34%), Gaps = 5/107 (4%)

Query: 147 PGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTS 206
           P   GPAA   ++ G    P   ++         P  P A+           P P  P +
Sbjct: 572 PAPAGPAATTVLQ-GVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPA 630

Query: 207 RGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAP-PGPNAAAHP 252
                 L  + P  + PP  P  ++    APP    P P P  A+ P
Sbjct: 631 VSTPLPLGLQQPQAQQPPQAPTPQA---AAPPQATTPQPSPGLASSP 674



 Score = 28.5 bits (62), Expect = 8.2
 Identities = 44/175 (25%), Positives = 62/175 (35%), Gaps = 22/175 (12%)

Query: 116 PQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTSLAQAS 175
           P +L  +L P      A +      A+P ++  G+       V    G  P  +  A A 
Sbjct: 523 PLSLGPVLAPHSGAHSAHILS----AAPIQV--GQPALFQMPVSLAAGSLPTQSQPAPAG 576

Query: 176 RSGTVP----GLPPASLQPLRVP--YFAPPGPHDPTSRGPGRLLTRE----PPSRKLPPP 225
            + T       LPP+++  L  P     P  P   T      L  +     PP+   P P
Sbjct: 577 PAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLP 636

Query: 226 LPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPPRARLQDPVDPERCPGG--PSRGP 278
           L L + +       PP  P P AAA P    P+        PE+   G  PS  P
Sbjct: 637 LGLQQPQ----AQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATP 687


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 63/233 (27%), Positives = 88/233 (37%), Gaps = 35/233 (15%)

Query: 90  PEPGRGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGS----------- 138
           P P      Q   G  G P +P    P     L G G  G  + LQ G            
Sbjct: 264 PHPSPHPPLQPLTGSAGQPSAPSHAQPP----LHGQGPPGPHS-LQAGPLLQHPGPPQPF 318

Query: 139 ---SGASPRRLPGGRGPAAAFAVEPGTG-QRPRNTSLAQASRSGTVPGLPPASLQPLRVP 194
                AS  + P G  PAAA+   P T  Q P + S  Q+ +      LPPA   PL +P
Sbjct: 319 GLPPQASQGQAPLGTSPAAAY---PHTSLQLPASQSALQSQQPPREQPLPPA---PLAMP 372

Query: 195 YFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAAAH--P 252
           +  PP P  P  + P     + PP    P P  +  +     PPPP   P  + + H  P
Sbjct: 373 HIKPP-PTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN----LPPPPALKPLSSLSTHHPP 427

Query: 253 PLRPPRARLQDPVDPERCPGGPSRGPGHGTHAHSELPTCTRLPSVVFRASGRP 305
              PP  +L     P   P  P++ PG     +   P  +  P+ + + + +P
Sbjct: 428 SAHPPPLQLMPQSQP--LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQP 478



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 42/174 (24%), Positives = 58/174 (33%), Gaps = 26/174 (14%)

Query: 105 TGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVE-PGTG 163
           T  PQ P P A +    L GP      A L            P    P ++ +   P + 
Sbjct: 380 TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP----------PPALKPLSSLSTHHPPSA 429

Query: 164 QRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLP 223
             P    + Q+    + P  PP   Q   +P   PP  H PT               ++ 
Sbjct: 430 HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLP--PPPASHPPTGL------------HQVA 475

Query: 224 PPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPPRARLQDPVDPERCPGGPSRG 277
           P  P  +  +V   PPP  PP   + + PP  P  +  Q P       GG   G
Sbjct: 476 PQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTS-AQPPCSGAAASGGSIAG 528



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 30/104 (28%), Positives = 40/104 (38%), Gaps = 10/104 (9%)

Query: 184 PPASLQPLRVPYFAPPGPHDPTSRGP--GRLLTREPPSRKLPPPLPLCRSRWVLAP---- 237
           P  S  P   P    PGP    +  P  G     + P++   P  P+  +    AP    
Sbjct: 195 PAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHP 254

Query: 238 --PPPPAPPGPNAAAHPPLRPPRARLQDPVDPERC-PGGPSRGP 278
             PP P PP P+ + HPPL+P       P  P    P    +GP
Sbjct: 255 QRPPSPHPP-PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP 297



 Score = 35.8 bits (81), Expect = 0.051
 Identities = 44/137 (32%), Positives = 51/137 (37%), Gaps = 28/137 (20%)

Query: 147 PGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTVP--GLPPASLQPLRVPYFAPPGPHDP 204
           P G  PA + A  PGT Q P       A+    VP  G P AS  P +      P PH  
Sbjct: 190 PTGVTPAPSSA-PPGTPQLPTPGPTPSAT---AVPPQGSPTASQAPNQPQAPTAPVPHTH 245

Query: 205 TSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAP-------PGPNAAAHPPLRPP 257
             + P  L  + PPS   PPP P        +P PP  P       P   + A PPL   
Sbjct: 246 IQQAPA-LHPQRPPSPH-PPPHP--------SPHPPLQPLTGSAGQPSAPSHAQPPLHG- 294

Query: 258 RARLQDPVDPERCPGGP 274
               Q P  P     GP
Sbjct: 295 ----QGPPGPHSLQAGP 307


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 63/233 (27%), Positives = 88/233 (37%), Gaps = 35/233 (15%)

Query: 90   PEPGRGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGS----------- 138
            P P      Q   G  G P +P    P     L G G  G  + LQ G            
Sbjct: 818  PHPSPHPPLQPLTGSAGQPSAPSHAQPP----LHGQGPPGPHS-LQAGPLLQHPGPPQPF 872

Query: 139  ---SGASPRRLPGGRGPAAAFAVEPGTG-QRPRNTSLAQASRSGTVPGLPPASLQPLRVP 194
                 AS  + P G  PAAA+   P T  Q P + S  Q+ +      LPPA   PL +P
Sbjct: 873  GLPPQASQGQAPLGTSPAAAY---PHTSLQLPASQSALQSQQPPREQPLPPA---PLAMP 926

Query: 195  YFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAAAH--P 252
            +  PP P  P  + P     + PP    P P  +  +     PPPP   P  + + H  P
Sbjct: 927  HIKPP-PTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN----LPPPPALKPLSSLSTHHPP 981

Query: 253  PLRPPRARLQDPVDPERCPGGPSRGPGHGTHAHSELPTCTRLPSVVFRASGRP 305
               PP  +L     P   P  P++ PG     +   P  +  P+ + + + +P
Sbjct: 982  SAHPPPLQLMPQSQP--LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQP 1032



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 42/174 (24%), Positives = 58/174 (33%), Gaps = 26/174 (14%)

Query: 105  TGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVE-PGTG 163
            T  PQ P P A +    L GP      A L            P    P ++ +   P + 
Sbjct: 934  TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP----------PPALKPLSSLSTHHPPSA 983

Query: 164  QRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLP 223
              P    + Q+    + P  PP   Q   +P   PP  H PT               ++ 
Sbjct: 984  HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLP--PPPASHPPTGL------------HQVA 1029

Query: 224  PPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPPRARLQDPVDPERCPGGPSRG 277
            P  P  +  +V   PPP  PP   + + PP  P  +  Q P       GG   G
Sbjct: 1030 PQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTS-AQPPCSGAAASGGSIAG 1082



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 30/104 (28%), Positives = 40/104 (38%), Gaps = 10/104 (9%)

Query: 184 PPASLQPLRVPYFAPPGPHDPTSRGP--GRLLTREPPSRKLPPPLPLCRSRWVLAP---- 237
           P  S  P   P    PGP    +  P  G     + P++   P  P+  +    AP    
Sbjct: 749 PAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHP 808

Query: 238 --PPPPAPPGPNAAAHPPLRPPRARLQDPVDPERC-PGGPSRGP 278
             PP P PP P+ + HPPL+P       P  P    P    +GP
Sbjct: 809 QRPPSPHPP-PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP 851



 Score = 35.8 bits (81), Expect = 0.051
 Identities = 44/137 (32%), Positives = 51/137 (37%), Gaps = 28/137 (20%)

Query: 147 PGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTVP--GLPPASLQPLRVPYFAPPGPHDP 204
           P G  PA + A  PGT Q P       A+    VP  G P AS  P +      P PH  
Sbjct: 744 PTGVTPAPSSA-PPGTPQLPTPGPTPSAT---AVPPQGSPTASQAPNQPQAPTAPVPHTH 799

Query: 205 TSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAP-------PGPNAAAHPPLRPP 257
             + P  L  + PPS   PPP P        +P PP  P       P   + A PPL   
Sbjct: 800 IQQAPA-LHPQRPPSPH-PPPHP--------SPHPPLQPLTGSAGQPSAPSHAQPPLHG- 848

Query: 258 RARLQDPVDPERCPGGP 274
               Q P  P     GP
Sbjct: 849 ----QGPPGPHSLQAGP 861


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 63/233 (27%), Positives = 88/233 (37%), Gaps = 35/233 (15%)

Query: 90   PEPGRGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGS----------- 138
            P P      Q   G  G P +P    P     L G G  G  + LQ G            
Sbjct: 818  PHPSPHPPLQPLTGSAGQPSAPSHAQPP----LHGQGPPGPHS-LQAGPLLQHPGPPQPF 872

Query: 139  ---SGASPRRLPGGRGPAAAFAVEPGTG-QRPRNTSLAQASRSGTVPGLPPASLQPLRVP 194
                 AS  + P G  PAAA+   P T  Q P + S  Q+ +      LPPA   PL +P
Sbjct: 873  GLPPQASQGQAPLGTSPAAAY---PHTSLQLPASQSALQSQQPPREQPLPPA---PLAMP 926

Query: 195  YFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAAAH--P 252
            +  PP P  P  + P     + PP    P P  +  +     PPPP   P  + + H  P
Sbjct: 927  HIKPP-PTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN----LPPPPALKPLSSLSTHHPP 981

Query: 253  PLRPPRARLQDPVDPERCPGGPSRGPGHGTHAHSELPTCTRLPSVVFRASGRP 305
               PP  +L     P   P  P++ PG     +   P  +  P+ + + + +P
Sbjct: 982  SAHPPPLQLMPQSQP--LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQP 1032



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 42/174 (24%), Positives = 58/174 (33%), Gaps = 26/174 (14%)

Query: 105  TGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVE-PGTG 163
            T  PQ P P A +    L GP      A L            P    P ++ +   P + 
Sbjct: 934  TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP----------PPALKPLSSLSTHHPPSA 983

Query: 164  QRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLP 223
              P    + Q+    + P  PP   Q   +P   PP  H PT               ++ 
Sbjct: 984  HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLP--PPPASHPPTGL------------HQVA 1029

Query: 224  PPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPPRARLQDPVDPERCPGGPSRG 277
            P  P  +  +V   PPP  PP   + + PP  P  +  Q P       GG   G
Sbjct: 1030 PQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTS-AQPPCSGAAASGGSIAG 1082



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 30/104 (28%), Positives = 40/104 (38%), Gaps = 10/104 (9%)

Query: 184 PPASLQPLRVPYFAPPGPHDPTSRGP--GRLLTREPPSRKLPPPLPLCRSRWVLAP---- 237
           P  S  P   P    PGP    +  P  G     + P++   P  P+  +    AP    
Sbjct: 749 PAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHP 808

Query: 238 --PPPPAPPGPNAAAHPPLRPPRARLQDPVDPERC-PGGPSRGP 278
             PP P PP P+ + HPPL+P       P  P    P    +GP
Sbjct: 809 QRPPSPHPP-PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP 851



 Score = 35.8 bits (81), Expect = 0.051
 Identities = 44/137 (32%), Positives = 51/137 (37%), Gaps = 28/137 (20%)

Query: 147 PGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTVP--GLPPASLQPLRVPYFAPPGPHDP 204
           P G  PA + A  PGT Q P       A+    VP  G P AS  P +      P PH  
Sbjct: 744 PTGVTPAPSSA-PPGTPQLPTPGPTPSAT---AVPPQGSPTASQAPNQPQAPTAPVPHTH 799

Query: 205 TSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAP-------PGPNAAAHPPLRPP 257
             + P  L  + PPS   PPP P        +P PP  P       P   + A PPL   
Sbjct: 800 IQQAPA-LHPQRPPSPH-PPPHP--------SPHPPLQPLTGSAGQPSAPSHAQPPLHG- 848

Query: 258 RARLQDPVDPERCPGGP 274
               Q P  P     GP
Sbjct: 849 ----QGPPGPHSLQAGP 861


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 59/201 (29%), Positives = 77/201 (38%), Gaps = 17/201 (8%)

Query: 92  PGRGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGG-R 150
           P +GG   +     G PQ P P       S   P         QGG+    P   PG  +
Sbjct: 205 PPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 264

Query: 151 GPAAAFAVEPG--------TGQRPRNTSLAQASRS--GTVPGLPP-ASLQPLRVPYFAPP 199
           GP      +P          G  P+  S +++SRS  G   G PP    QP   P   PP
Sbjct: 265 GPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPP--PPP 322

Query: 200 G-PHDPTSRGPGRLLTREPPSRKL-PPPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPP 257
           G P  P  +G  +     PP +   PPP    +SR   +PP  P  P P    + P  PP
Sbjct: 323 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGP-PQQEGNNPQGPP 381

Query: 258 RARLQDPVDPERCPGGPSRGP 278
                +P  P+  P G  +GP
Sbjct: 382 PPAGGNPQQPQAPPAGQPQGP 402



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 68/255 (26%), Positives = 89/255 (34%), Gaps = 33/255 (12%)

Query: 58  PGTQRGVREVGSPTRDQEIRAGSSCGRAARGF-------PEPGR-------GGKTQEWGG 103
           PG  +G    G  +R      G   G   +G        P PG+       GG   +   
Sbjct: 95  PGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 154

Query: 104 GTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGG-RGPAAAFAVEPG- 161
             G PQ P P       S   P         QGG+    P   PG  +GP      +P  
Sbjct: 155 PPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 214

Query: 162 -------TGQRPRNTSLAQASRS--GTVPGLPP-ASLQPLRVPYFAPPG-PHDPTSRGPG 210
                   G  P+  + +Q++RS  G   G PP    QP   P   PPG P  P  +G  
Sbjct: 215 PPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPP--PPPGKPQGPPPQGGN 272

Query: 211 RLLTREPPSRKL-PPPLPLCRSRWVLAPPPPPA---PPGPNAAAHPPLRPPRARLQDPVD 266
           +     PP +   PPP    +SR   +PP  P    P G N    PP  P + +   P  
Sbjct: 273 KPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 332

Query: 267 PERCPGGPSRGPGHG 281
             +  G P  G   G
Sbjct: 333 GNKPQGPPPPGKPQG 347



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 58/207 (28%), Positives = 80/207 (38%), Gaps = 20/207 (9%)

Query: 92  PGRGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGG-R 150
           P +GG   +     G PQ P P   ++ +    PGK       QGG+    P   PG  +
Sbjct: 82  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP-QGGNQPQGPPPPPGKPQ 140

Query: 151 GPAAAFAVEPG--------TGQRPRNTSLAQASRS--GTVPGLPP-ASLQPLRVPYFAPP 199
           GP      +P          G  P+  + +++SRS  G   G PP    QP   P   PP
Sbjct: 141 GPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPP--PPP 198

Query: 200 G-PHDPTSRGPGRLLTREPPSRKL-PPPLPLCRSRWVLAPPPPPA---PPGPNAAAHPPL 254
           G P  P  +G  +     PP +   PPP    +S+   +PP  P    P G N    PP 
Sbjct: 199 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPP 258

Query: 255 RPPRARLQDPVDPERCPGGPSRGPGHG 281
            P + +   P    +  G P  G   G
Sbjct: 259 PPGKPQGPPPQGGNKPQGPPPPGKPQG 285



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 58/220 (26%), Positives = 75/220 (34%), Gaps = 14/220 (6%)

Query: 70  PTRDQEIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAG 129
           P  D + R+  S     +G P P  G + Q      G PQ P P           PGK  
Sbjct: 164 PQGDNKSRSSRSPPGKPQG-PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 222

Query: 130 CRARLQGGSSGASPRRLPGG-RGPAAAFAVEPGTGQRPRNTSLAQASRSGTVPGLPPASL 188
                QG +   S R  PG  +GP      +P     P         + G  P  PP   
Sbjct: 223 GPPP-QGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 281

Query: 189 QPLRVP---------YFAPPG-PHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPP 238
           +P   P           +PPG P  P  +G  +     PP  K   P P   ++    PP
Sbjct: 282 KPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK-PQGPP 340

Query: 239 PPPAPPGPNAAAHPPLRPPRARLQDPVDPERCPGGPSRGP 278
           PP  P GP        R  R+    P  P +  G   +GP
Sbjct: 341 PPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGP 380



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 44/168 (26%), Positives = 56/168 (33%), Gaps = 22/168 (13%)

Query: 135 QGGSSGASPRRLPGG-RGPAAAFAVEPGTGQRPRNTSLAQASRSGTVPGLPPASLQPL-- 191
           QGG+    P   PG  +GP      +P     P         + G  P  PP   +P   
Sbjct: 42  QGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 101

Query: 192 -------RVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAPP 244
                  R P   P  P  P  +G  +     PP  K   P P   ++    PPPP  P 
Sbjct: 102 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK-PQGPPPPGKPQ 160

Query: 245 GP--------NAAAHPPLR---PPRARLQDPVDPERCPGGPSRGPGHG 281
           GP         ++  PP +   PP      P  P   PG P   P  G
Sbjct: 161 GPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 208



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 52/200 (26%), Positives = 64/200 (32%), Gaps = 25/200 (12%)

Query: 90  PEPGRGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGG 149
           P P  G + Q      G PQ P P           PGK   +     G    SPR  PG 
Sbjct: 60  PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP--QGPPPQGDKSRSPRSPPGK 117

Query: 150 -RGPAAAFAVEPGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRG 208
            +GP      +P     P         + G  P  PP   +P       PP   D  SR 
Sbjct: 118 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ-----GPPPQGDNKSRS 172

Query: 209 PGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPPRA--RLQDPVD 266
                +R PP +   PP              P  PP P      P  PP+   + Q P  
Sbjct: 173 -----SRSPPGKPQGPPPQ--------GGNQPQGPPPPPGKPQGP--PPQGGNKPQGPPP 217

Query: 267 PERCPGGPSRGPGHGTHAHS 286
           P +  G P +G      A S
Sbjct: 218 PGKPQGPPPQGDNKSQSARS 237



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 60/204 (29%), Positives = 72/204 (35%), Gaps = 26/204 (12%)

Query: 87  RGFPEPGRGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRL 146
           +G P  G G K Q      G PQ P    PQ      GP          G   G  P+  
Sbjct: 37  QGAPPQG-GNKPQGPPSPPGKPQGP---PPQGGNQPQGPPPP------PGKPQGPPPQ-- 84

Query: 147 PGGRGPAAAFAVEPGTGQRPR---NTSLAQASRSGTVPGLPP-ASLQPLRVPYFAPPG-P 201
            GG  P       PG  Q P    + S +  S  G   G PP    QP   P   PPG P
Sbjct: 85  -GGNKPQGP--PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP--PPPGKP 139

Query: 202 HDPTSRGPGRLLTREPPSRKL-PPPLPLCRSRWVLAPPPPPA---PPGPNAAAHPPLRPP 257
             P  +G  +     PP +   PPP    +SR   +PP  P    P G N    PP  P 
Sbjct: 140 QGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG 199

Query: 258 RARLQDPVDPERCPGGPSRGPGHG 281
           + +   P    +  G P  G   G
Sbjct: 200 KPQGPPPQGGNKPQGPPPPGKPQG 223



 Score = 36.6 bits (83), Expect = 0.030
 Identities = 29/105 (27%), Positives = 36/105 (34%), Gaps = 2/105 (1%)

Query: 177 SGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLA 236
           +G   G PP      + P   P  P  P  +G  +     PP  K   P P   ++    
Sbjct: 33  AGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 92

Query: 237 PPP--PPAPPGPNAAAHPPLRPPRARLQDPVDPERCPGGPSRGPG 279
           PPP  P  PP     +  P  PP      P      P GP   PG
Sbjct: 93  PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPG 137


>gi|169215850 PREDICTED: transmembrane protein 46-like [Homo
           sapiens]
          Length = 547

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 75/241 (31%), Positives = 87/241 (36%), Gaps = 37/241 (15%)

Query: 44  EERRGWKQRGRNGAPGTQRGVREVGSPTRDQE--IRAGSSCGRAARGFPEPGRGGKTQEW 101
           E+R G + R  NG PG+ R     G    D E  +  G    R +   P+  R       
Sbjct: 268 EDRLGSQPRPENGPPGSHRTASGRGLRRGDSEGGVNRGIGPSRVSLLAPDKKRLNNAPRG 327

Query: 102 GGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPR------RLPGGRGPAAA 155
               G P+ P      +L   L P  A            A PR      RLP   GP   
Sbjct: 328 SAAPGPPRGPRLQGGGSLT--LQPDYAKYATFKAAALKAAVPRARRSANRLPRPSGPRPR 385

Query: 156 FAVEPGTGQRPRNTS---LAQASRSG-TVPGLPPASLQPLRVPYFAP---PGPHDPTSRG 208
            A      Q P  T    L+  +R G T+P   PA   P       P   P P  P +R 
Sbjct: 386 PAPARSPSQSPAGTPCPVLSLGARRGVTLPCPVPAEAAPRDFCQRFPALEPSPRQPPARA 445

Query: 209 PGRLLTREPPSRKLPPPLPLCRSRWVLAPP--PPPAPPGPNAA------AHP-PLRPPRA 259
           P        PS  LP PL  C   W  APP   PPA PGP AA      A P PL  P A
Sbjct: 446 PR-------PSPDLPAPLDACP--W--APPVYAPPAAPGPYAAWTSSRPARPAPLSHPTA 494

Query: 260 R 260
           R
Sbjct: 495 R 495



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 57/204 (27%), Positives = 70/204 (34%), Gaps = 44/204 (21%)

Query: 92  PGRGGKTQ-EWGGGT--GTPQ-SPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLP 147
           P  GG  Q + G G   G+P  S GP  P+ LA    PG+   R    G ++ A+ R   
Sbjct: 198 PPLGGCVQVQMGDGLPRGSPHNSAGPRTPR-LARASPPGEPFMRVAPPGLAAAAAARDSE 256

Query: 148 GGRGPAAAFAVEPGTGQRPR---------NTSLAQASRSGTVPGLPPASLQPLRVPYFAP 198
            G  P A    E   G +PR          T+  +  R G   G     + P RV   AP
Sbjct: 257 PGPVPGAGGCGEDRLGSQPRPENGPPGSHRTASGRGLRRGDSEGGVNRGIGPSRVSLLAP 316

Query: 199 --------------PGPHDPTSRGP----GRLLTREPPSRK--------LPPPLPLCRSR 232
                         PGP     RGP    G  LT +P   K        L   +P  R  
Sbjct: 317 DKKRLNNAPRGSAAPGP----PRGPRLQGGGSLTLQPDYAKYATFKAAALKAAVPRARRS 372

Query: 233 WVLAPPPPPAPPGPNAAAHPPLRP 256
               P P    P P  A  P   P
Sbjct: 373 ANRLPRPSGPRPRPAPARSPSQSP 396


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 75/263 (28%), Positives = 89/263 (33%), Gaps = 41/263 (15%)

Query: 52  RGRNGAPGTQRGVREVGSPTRDQEIRAGSSCGRAARGFPE----PGRGGKTQEWG----- 102
           RG  G PG      E G      E+    S G  ARGFP     PG  G     G     
Sbjct: 254 RGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPG--ARGFPGAPGLPGLKGHRGHKGLEGPK 311

Query: 103 ---GGTGTPQSPGPCAPQALASLLGP-GKAGCRARL--QGGSSGASPRRLPGGRGPAAAF 156
              G  G+    GP  P      LGP G  G R RL  QG         +PG  GP    
Sbjct: 312 GEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPL 371

Query: 157 AVEPGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGP-------------HD 203
            + PG+   P N  +     +G      P   Q  R     PPGP               
Sbjct: 372 GI-PGSSGFPGNPGMK--GEAGPTGARGPEGPQGQRGET-GPPGPVGSPGLPGAIGTDGT 427

Query: 204 PTSRGP-GRLLTREPPSRKLPPPLPLCRS----RWVLAPPPPPAPPGPNAAAHPPLRPPR 258
           P ++GP G   T  PP    PP  P  +     + +   P  P  PG    A P   P  
Sbjct: 428 PGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGP 487

Query: 259 ARLQDPVDP--ERCPGGPSRGPG 279
             +Q P+ P  E    GP   PG
Sbjct: 488 HGIQGPIGPPGEEGKRGPRGDPG 510



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 65/222 (29%), Positives = 80/222 (36%), Gaps = 54/222 (24%)

Query: 53   GRNGAPGTQRGVREVGSPTRDQEIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQSPG 112
            G  G PG +      G+P RD     G+   R  RG  +PG  G      G  G P +PG
Sbjct: 1041 GPVGEPGPEGPAGNDGTPGRD-----GAVGERGDRG--DPGPAGLP----GSQGAPGTPG 1089

Query: 113  PCAPQALASLLGPGKAGCRARLQGGSSG-------ASPRRLPGGRGPAAAFAVEPGTGQR 165
            P           PG AG R     GS G       A  R LPG +GP          G R
Sbjct: 1090 PVG--------APGDAGQRG--DPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDR 1139

Query: 166  PRNTSLAQASRSGTVPGLPPASLQP----LRVPYF--APPGPHDPTSR--GPGRLLTREP 217
             +          G +PG P  + +     +  P+    PPGP  P+ +   PG L    P
Sbjct: 1140 GQKGHRGFTGLQG-LPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGP 1198

Query: 218  PSRKL---------PPPLPLCRSRWVLAPPPPPAPPGPNAAA 250
            P  +          PP  P         PP PP PPG   AA
Sbjct: 1199 PGVRGSVGEAGPEGPPGEP--------GPPGPPGPPGHLTAA 1232



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 74/266 (27%), Positives = 81/266 (30%), Gaps = 40/266 (15%)

Query: 51   QRGRNGAPGTQRGVREVGSPTRDQEIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQS 110
            Q G  G PG      + GSP    +  AGS       G P    G  TQ   G TG P S
Sbjct: 856  QPGVKGEPGEPGQKGDAGSP--GPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGS 913

Query: 111  PGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTS 170
             G   P   A   GP               A P   PG  GP      +PG+  R  +  
Sbjct: 914  AGRVGPPGPAGAPGP---------------AGPLGEPGKEGPPGLRG-DPGSHGRVGDRG 957

Query: 171  LAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTS-RG----PGRLLTREPPSRKLPPP 225
             A         G P    QP       PPGP   T  RG    PG+   R  P    P  
Sbjct: 958  PAGPPGGPGDKGDPGEDGQP---GPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAG 1014

Query: 226  LP----LCRSRWVLAPPPPPAPPGPNAAAHPPLRPPRARLQDPVDPERCPGGPSRGPGHG 281
             P       +     PP P  PPG N     P          P  P    G P R    G
Sbjct: 1015 TPGKVGPTGATGDKGPPGPVGPPGSNGPVGEP---------GPEGPAGNDGTPGRDGAVG 1065

Query: 282  THAHSELPTCTRLPSVVFRASGRPYP 307
                   P    LP     A G P P
Sbjct: 1066 ERGDRGDPGPAGLPGSQ-GAPGTPGP 1090



 Score = 35.8 bits (81), Expect = 0.051
 Identities = 52/203 (25%), Positives = 65/203 (32%), Gaps = 24/203 (11%)

Query: 87  RGFPEPGRGGKTQEWGGGTGTPQSPGPCAPQALASLLG-PGKAGCRARLQGGSSGASPRR 145
           RG P P     +Q   G  G    PGP  PQ +    G PG+ G       G  G     
Sbjct: 128 RGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGA-----PGPPGHPSH- 181

Query: 146 LPGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPT 205
            PG  G +  F+ +           L + S  G+  GL P S+ P+      P GP    
Sbjct: 182 -PGPDGLSRPFSAQ--------MAGLDEKSGLGSQVGLMPGSVGPV-----GPRGPQGLQ 227

Query: 206 SRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPPRARLQDPV 265
            +  G   T  P     P P+    SR    P  PP  PG +        P         
Sbjct: 228 GQQGGAGPTGPPGEPGDPGPMGPIGSR---GPEGPPGKPGEDGEPGRNGNPGEVGFAGSP 284

Query: 266 DPERCPGGPSRGPGHGTHAHSEL 288
                PG P      G   H  L
Sbjct: 285 GARGFPGAPGLPGLKGHRGHKGL 307



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 61/230 (26%), Positives = 73/230 (31%), Gaps = 42/230 (18%)

Query: 51  QRGRNGAPGTQRGVREVGSPTRDQEIRAGSSCGRAARGFPEP-GRGGKTQEWG--GGTGT 107
           + G  G PG       +G P        G    R  RG P   G  G   E G  G  G 
Sbjct: 478 EAGPKGEPGPHGIQGPIGPP--------GEEGKRGPRGDPGTVGPPGPVGERGAPGNRGF 529

Query: 108 PQSPGPCAPQALASLLGP-GKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRP 166
           P S G   P+      GP G +G +   QG         LPG RG      V+   G+  
Sbjct: 530 PGSDGLPGPKGAQGERGPVGSSGPKGS-QGDPGRPGEPGLPGARGLTGNPGVQGPEGKLG 588

Query: 167 RNTSLAQASRSGTVPGLPPASL----QPLRVPYFAPPGPHD-------------PTSRGP 209
              +  +  R G     PP S+    QP  +    P G                P  RG 
Sbjct: 589 PLGAPGEDGRPG-----PPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGA 643

Query: 210 GRLLTREPPSRKLPPPLPLCRSRWVLAPPPP------PAPPGPNAAAHPP 253
                   PS  + PP  L   R    PP P      P PPGP      P
Sbjct: 644 PGKDGEVGPSGPVGPP-GLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKP 692


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 69/237 (29%), Positives = 80/237 (33%), Gaps = 40/237 (16%)

Query: 53  GRNGAPGTQRGVREVGSPTRDQEIRAGSSCGRAARGFP-------EPGRGGKTQEWG--- 102
           G  G PGT+     +G          G    R   G P       EPG  G+  E G   
Sbjct: 296 GAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQG 355

Query: 103 --------GGTGTPQSPGPCAPQALASLLGP-GKAGCR-----ARLQGGSSGASPRRLPG 148
                   G  G P   GP  P+  A   GP G  G R     + L G       R LPG
Sbjct: 356 LGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPG 415

Query: 149 GRGPAAAFAV--EPGTGQRPRNTSLAQASRSGTVPGLP--PASLQPLRVPYF-APPGPHD 203
             GP        EPG   RP    +A A       GLP  P    P  +P    P GP  
Sbjct: 416 AHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIG 475

Query: 204 PTS----RG-------PGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAA 249
           P      +G       PG     EP +     P  +  S  +  PP PP PPGP  A
Sbjct: 476 PQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGA 532



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 69/243 (28%), Positives = 84/243 (34%), Gaps = 57/243 (23%)

Query: 53  GRNGAPGTQR--GVREVGSPTRDQEIRAGSSCGRAARGFP-EPGRGGKTQEWG--GGTGT 107
           G+ GAPG     G   +G P  D              G P  PG  G++   G  G  G 
Sbjct: 220 GQGGAPGPPGLPGPAGLGKPGLD--------------GLPGAPGDKGESGPPGVPGPRGE 265

Query: 108 PQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPR 167
           P + GP  P  +  +  PG AG                LPG +GP+ A   EPGT   P 
Sbjct: 266 PGAVGPKGPPGVDGVGVPGAAG----------------LPGPQGPSGAKG-EPGTRGPP- 307

Query: 168 NTSLAQASRSGTVPGLP-------PASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSR 220
              L   +  G +PGLP       PA +  L      P    +P  +GP  L        
Sbjct: 308 --GLIGPTGYG-MPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGL-------- 356

Query: 221 KLPPPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPPRARLQDPVDPERCPGGPSRGPGH 280
             PP LP   S  +     PP P G      PP  P     Q P      PG P      
Sbjct: 357 GGPPGLP--GSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLP 414

Query: 281 GTH 283
           G H
Sbjct: 415 GAH 417



 Score = 35.8 bits (81), Expect = 0.051
 Identities = 62/208 (29%), Positives = 71/208 (34%), Gaps = 30/208 (14%)

Query: 91  EPG----RGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQG-----GSSGA 141
           EPG    RG K     G  G P +PG         L GP   G +  L G     G  G 
Sbjct: 195 EPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLG-KPGLDGLPGAPGDKGE 253

Query: 142 S-PRRLPGGRGPAAAFAVEPGT--GQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAP 198
           S P  +PG RG       EPG    + P          +  +PG    S          P
Sbjct: 254 SGPPGVPGPRG-------EPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGP 306

Query: 199 PGPHDPTSRG-PGRLLTREPPSRKLPPPLP-LCRSRWVLAPPPPPAPPGPNAAAHPPLRP 256
           PG   PT  G PG      P   + P  +P L   R        P   GP     PP  P
Sbjct: 307 PGLIGPTGYGMPG---LPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLP 363

Query: 257 PRARL---QDPVDP--ERCPGGPSRGPG 279
             A L   + P  P  E  PGGP   PG
Sbjct: 364 GSAGLPGRRGPPGPKGEAGPGGPPGVPG 391



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 2/80 (2%)

Query: 196 FAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLR 255
           +AP     P  +GP     RE   + L  PLPL     +   P PP  PGP     PP  
Sbjct: 38  YAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMD-LKGEPGPPGKPGPRGPPGPPGF 96

Query: 256 PPRARLQDP-VDPERCPGGP 274
           P +  +  P +  +  P GP
Sbjct: 97  PGKPGMGKPGLHGQPGPAGP 116


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 54/193 (27%), Positives = 68/193 (35%), Gaps = 14/193 (7%)

Query: 87  RGFPEPGRGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRL 146
           R  P+      T + GGG+   +  G   P  L  L   G    R   Q   +G    + 
Sbjct: 68  RSAPQIESSKGTNKEGGGSANTR--GASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQG 125

Query: 147 PGGRGPAAAFAVE-------PGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPP 199
           PG R P+     +       P    R  NTS A  +     P     +  P   P   PP
Sbjct: 126 PGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPP 185

Query: 200 GPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPPRA 259
            P    S  P +     PP       LP+       APPPPP PP P     PP  PP +
Sbjct: 186 LPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPT----PPPLPPAS 241

Query: 260 RLQD-PVDPERCP 271
            L D  V P+  P
Sbjct: 242 VLSDKAVKPQLAP 254



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 38/106 (35%), Positives = 44/106 (41%), Gaps = 22/106 (20%)

Query: 179 TVPGLPPAS----------LQPLRVPYFAPPGPHDPTSRGPGRLL--------TREPPSR 220
           T P LPPAS          L PL +P   PP P  P    PG            +EPP+ 
Sbjct: 233 TPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAP 292

Query: 221 KLPPPLPLCRSRWVLAPPPPPAPPGPNAAAH--PPLRPPRARLQDP 264
             PPPLP   S    A  P P  PG N+++   PPL P     Q P
Sbjct: 293 --PPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAP 336



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 64/238 (26%), Positives = 80/238 (33%), Gaps = 44/238 (18%)

Query: 52  RGRNGAPGTQRGVREVGSPTRDQEIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGT---P 108
           +G N   G     R   +P    ++ AG        GFP     G+    GG TG     
Sbjct: 77  KGTNKEGGGSANTRGASTPPTLGDLFAG--------GFPVLRPAGQRDVAGGKTGQGPGS 128

Query: 109 QSPGPCAPQALAS--LLGPG--KAGCRARLQGGSSGASPR-RLPGGRGPAAAFAVEPGTG 163
           ++P P  P    S  L+ P   + G  +   G +  A PR  +P    P       P   
Sbjct: 129 RAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPT------PPPP 182

Query: 164 QRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREP--PSRK 221
             P    L  +S   T    PP  L    +P  APP P  P    P    T  P  P+  
Sbjct: 183 PPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASV 242

Query: 222 L-----------------PPPLPL---CRSRWVLAPPPPPAPPGPNAAAHPPLRPPRA 259
           L                 PPPLPL   C    + A P  PA       A PP  PP A
Sbjct: 243 LSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYA 300



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 37/142 (26%), Positives = 45/142 (31%), Gaps = 30/142 (21%)

Query: 160 PGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPS 219
           PG    P + +          P LPP +    R    APP P   +S      L  + PS
Sbjct: 273 PGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPS 332

Query: 220 RKLPPPLPLCRSRWVLAPPPPPAPPGP-------------------NAAAHPPLRPPRAR 260
            + PP     +     A P PPAPPG                    N    PP R P   
Sbjct: 333 FQAPP-----QKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTE 387

Query: 261 LQDPVD------PERCPGGPSR 276
           L           P + PGG  R
Sbjct: 388 LSSKSQQATAWTPTQQPGGQLR 409



 Score = 32.7 bits (73), Expect = 0.43
 Identities = 13/23 (56%), Positives = 13/23 (56%)

Query: 237 PPPPPAPPGPNAAAHPPLRPPRA 259
           PPPPP PP P     PP  PP A
Sbjct: 6   PPPPPLPPPPPPLGAPPPPPPSA 28



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 18/37 (48%), Positives = 18/37 (48%), Gaps = 16/37 (43%)

Query: 223 PPPLPLCRSRWVLAPPPPP--APPGPNAAAHPPLRPP 257
           PPPLP         PPPPP  APP P     PP  PP
Sbjct: 8   PPPLP---------PPPPPLGAPPPP-----PPSAPP 30



 Score = 28.9 bits (63), Expect = 6.2
 Identities = 14/30 (46%), Positives = 14/30 (46%), Gaps = 6/30 (20%)

Query: 217 PPSRKLPPPLPLCRSRWVLAPPPPPAPPGP 246
           PP   LPPP P       L  PPPP P  P
Sbjct: 6   PPPPPLPPPPP------PLGAPPPPPPSAP 29


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 56/186 (30%), Positives = 69/186 (37%), Gaps = 32/186 (17%)

Query: 131 RARLQGGSSGASPRRLPGG-RGPAAAF-AVEPGTG----QRPRNTSLAQASRSGTVPGLP 184
           R R +GG  G   RR  GG RG    F +  PG G    + P      Q+     +P  P
Sbjct: 5   RFRSRGGGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPP 64

Query: 185 PASLQPLRVPYFAPPG---PHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPP 241
           P   Q    P   PP    PH P           +P  ++ PPP P   S+ V+A  P P
Sbjct: 65  PHQQQQQPPPQQPPPQQPPPHQPPPHP-------QPHQQQQPPPPPQDSSKPVVAQGPGP 117

Query: 242 APPGPNAAAHPPLRPPRARLQDPVDPERCPGGPSRGPGHGTHAHSELPTCTRLPSVVFRA 301
           AP   +A       PP +    P  P      P  GPG         PT T  P+V    
Sbjct: 118 APGVGSA-------PPASSSAPPATPPTSGAPPGSGPG---------PTPTPPPAVTSAP 161

Query: 302 SGRPYP 307
            G P P
Sbjct: 162 PGAPPP 167



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 43/164 (26%), Positives = 50/164 (30%), Gaps = 23/164 (14%)

Query: 124 GPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTVPGL 183
           GPG A         SS A P   P    P  +     G G  P       ++  G  P  
Sbjct: 114 GPGPAPGVGSAPPASSSAPPATPPTSGAPPGS-----GPGPTPTPPPAVTSAPPGAPPPT 168

Query: 184 PPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAP 243
           PP+S  P   P    P P      GPG      P  ++ P P           P     P
Sbjct: 169 PPSSGVPTTPPQAGGPPPPPAAVPGPG------PGPKQGPGP---------GGPKGGKMP 213

Query: 244 PGPNAAAHPPLRPPRARLQDPVDPERCPGGPSRGPGHGTHAHSE 287
            GP     P L  P      P  P R  G P  G  H    H +
Sbjct: 214 GGPKPGGGPGLSTPGGH---PKPPHRGGGEPRGGRQHHPPYHQQ 254



 Score = 28.5 bits (62), Expect = 8.2
 Identities = 24/81 (29%), Positives = 30/81 (37%), Gaps = 1/81 (1%)

Query: 72  RDQEIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCR 131
           R++++R G   G    G P    G K    GGG G      P  P A  S    G     
Sbjct: 606 RERDMRMGGG-GAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATMSGSMMGSDMRT 664

Query: 132 ARLQGGSSGASPRRLPGGRGP 152
            R   G +G    + P G GP
Sbjct: 665 ERFGQGGAGPVGGQGPRGMGP 685


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 50/154 (32%), Positives = 58/154 (37%), Gaps = 13/154 (8%)

Query: 136 GGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTSLAQASRS-GTVPGLPPASLQPLRVP 194
           G S+ +S ++ P    P +     P  G  P     A   R  G   GLPP    P   P
Sbjct: 382 GTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGP-PPGAPP 440

Query: 195 YFAPPGPHDPTSRGP-GRLLTREPPSRKLPPPLPLCRSRWVLAPPP--------PPAPPG 245
           +  PPG   P  RGP  RLL   PP  + P P P         PPP        PPAPPG
Sbjct: 441 FLRPPGM--PGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPG 498

Query: 246 PNAAAHPPLRPPRARLQDPVDPERCPGGPSRGPG 279
                   +RPP      P  P   P  P   PG
Sbjct: 499 IPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPG 532



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 41/114 (35%), Positives = 47/114 (41%), Gaps = 20/114 (17%)

Query: 169 TSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPL 228
           TS A + +      +PP+ +Q       APP P  P   GP       PP+  L PP P 
Sbjct: 383 TSTASSQQQAPPQSVPPSQIQ-------APPMP-GPPPLGP-------PPAPPLRPPGPP 427

Query: 229 CRSRWVLAPPPPP-APPGPNAAAHPPLRPPRARLQDPVDPERCPGGPSRGPGHG 281
                 L P PPP APP       P LR P  RL  P  P   P GP  GP  G
Sbjct: 428 TG----LPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPG 477



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 55/171 (32%), Positives = 59/171 (34%), Gaps = 56/171 (32%)

Query: 102 GGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPG 161
           G  TG P  P P AP  L     PG  G R        G  PR LP G          P 
Sbjct: 425 GPPTGLPPGPPPGAPPFLRP---PGMPGLR--------GPLPRLLPPG----------PP 463

Query: 162 TGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRK 221
            G+ P           G  PG PP            PPGP  P    P RL    PP   
Sbjct: 464 PGRPP-----------GPPPGPPPG----------LPPGP--PPRGPPPRLPPPAPPG-- 498

Query: 222 LPPPLPLCRSRWVLAPPPPPAPPG---------PNAAAHPPLRPPRARLQD 263
           +PPP P    R  L PP  PAPPG         P   + PP    R +  D
Sbjct: 499 IPPPRP-GMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADD 548


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 64/198 (32%), Positives = 75/198 (37%), Gaps = 41/198 (20%)

Query: 92  PGRGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARL-----QGGSSGASPRRL 146
           P R   T    GG G+     P   QA  +L GPG      RL      GGSS  SPR L
Sbjct: 148 PCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGL-FPPRLADPVPSGGSS--SPRFL 204

Query: 147 PGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTS 206
           P G  P+ A    P       + +   A RS  VP               +PP PH  +S
Sbjct: 205 PRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPS-----------DLGSPPAPHASSS 253

Query: 207 RGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAAAH--PPLRPP--RARLQ 262
                     PPS    PPL  C      A  PPP PP  N  AH  P  +PP   A + 
Sbjct: 254 ----------PPS---DPPLFHCSD----ALTPPPLPPSNNLPAHPGPASQPPVSSATMH 296

Query: 263 DPVDPERCPGGPS-RGPG 279
            P+      G P+  GPG
Sbjct: 297 LPLVLGPLGGAPTVEGPG 314



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 52/177 (29%), Positives = 62/177 (35%), Gaps = 55/177 (31%)

Query: 179 TVPGLPPASLQPLRVPYFAP---------PGPHD-----PTSRGPGRLLTREPPSRKLPP 224
           TV   PP++  P RVP   P         P P       PT  GPG L    PP    P 
Sbjct: 137 TVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLF---PPRLADPV 193

Query: 225 PLPLCRSRWVL--------APPPPPA-------------------------PPGPNAAAH 251
           P     S   L        APPPPPA                         PP P+A++ 
Sbjct: 194 PSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSS 253

Query: 252 PPLRPPRARLQDPVDPERCPGGPSRG-PGH-GTHAHSELPTCT-RLPSVVFRASGRP 305
           PP  PP     D + P   P  PS   P H G  +   + + T  LP V+    G P
Sbjct: 254 PPSDPPLFHCSDALTPPPLP--PSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAP 308



 Score = 37.0 bits (84), Expect = 0.023
 Identities = 48/167 (28%), Positives = 67/167 (40%), Gaps = 20/167 (11%)

Query: 146 LPGGRGPAAAFAVEPGTGQRP--RNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHD 203
           LP   GP        G G  P   ++ L+ A+++   P  PP++LQ  R    AP   H 
Sbjct: 297 LPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHS 356

Query: 204 PTSRGPGRLLTREPPS--RKLPPPLPLCRSRWVLAPPPPPAP-PGPNAAAHP--PLRPPR 258
            + R P +   R PP+  R L    P    R   + P  PAP P P +   P  P+ P  
Sbjct: 357 SSLR-PSQRRPRRPPTVFRLLEGRGPQTPRR---SRPRAPAPVPQPFSLPEPSQPILPSV 412

Query: 259 ARLQDPVDPERCPGGPSRGPGHGTHAHSELPTCTRLPSVVFRASGRP 305
             L          G P+ GP H   + + L +   LP     +SG P
Sbjct: 413 LSLL---------GLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSP 450



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 67/229 (29%), Positives = 73/229 (31%), Gaps = 41/229 (17%)

Query: 108 PQSPGPCAPQALASL-LGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGT-GQR 165
           P  P P        L +G G A     L GG +   P    G     A F   PG  G  
Sbjct: 485 PVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGF---PGMLGAL 541

Query: 166 PRNTSLAQASRSGTVPG-----LPPASLQPLRVPYFAPPGPHDPT-----SRGPGRLLTR 215
           P   SL Q   S  +       L     QP   P   PPG   P        GP  L+  
Sbjct: 542 PLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVAS 601

Query: 216 EPPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPPRARLQDPVDPERCPGGPS 275
             P    PPP  L         PPP APP    A+  PL        D        GGPS
Sbjct: 602 LLP----PPPSDLL--------PPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPS 649

Query: 276 RGPGHGTHAHSEL--------PTCTRLPSVVFRA-----SGR-PYPCFL 310
             P  G    S L        PT   L S +  A     SG  P PC L
Sbjct: 650 GEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVL 698



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 59/217 (27%), Positives = 71/217 (32%), Gaps = 27/217 (12%)

Query: 90  PEPGRG-GKTQEWGGGTGTPQSP-GPCAPQALASLLGPG-----KAGCRARLQGGSSGAS 142
           P  G G G  +  GG +G P S  G  +P     L  P       +   A      SG  
Sbjct: 633 PTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTP 692

Query: 143 PRRLPGGRGPAAAFAVEPG--TGQRPRNTSLAQASRSGTVP---GLPPASLQPLRVPYFA 197
           P+       P    A +PG  T      T+   AS  G  P   G PP  L PL      
Sbjct: 693 PQ-------PCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLL 745

Query: 198 PPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPP 257
             G     +  PG L     PS  L PP PL   +  L   P    P P + A  PL   
Sbjct: 746 --GDLSSLTSSPGAL-----PSL-LQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACL 797

Query: 258 RARLQDPVDPERCPGGPSRGPGHGTHAHSELPTCTRL 294
              LQ P +    P  P   P          P  + L
Sbjct: 798 LQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSAL 834


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 62/235 (26%), Positives = 78/235 (33%), Gaps = 16/235 (6%)

Query: 53  GRNGAPGTQRGVREVGSPTRDQEIRAGSSCGRAARGF-------PEPGRGGKTQEWGGGT 105
           G+   P  Q G +  G P R      G   G+  +G        P PG+       GG  
Sbjct: 76  GKPEGPPPQGGNQSQGPPPRP-----GKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQ 130

Query: 106 GTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQR 165
                P P  P+      G    G   R  G   G  P+     +GP        G   +
Sbjct: 131 SQGPPPRPGKPEGPPPQGGNQSQGPPPR-PGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQ 189

Query: 166 PRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPP 225
             N S     R G   G PP      + P   P  P  P S+G  +     P   K   P
Sbjct: 190 GGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGP 249

Query: 226 LPLCRSRWVLAPPP--PPAPPGPNAAAHPPLRPPRARLQDPVDPERCPGGPSRGP 278
            P   ++    PPP  P  PP P      PL PP  + Q P  P +  G P R P
Sbjct: 250 PPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQ-GGRPHRPP 303



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 55/212 (25%), Positives = 72/212 (33%), Gaps = 15/212 (7%)

Query: 90  PEPGRGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGG 149
           P PG+       GG       P P  P+      G    G   R  G   G  P+     
Sbjct: 73  PRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPR-PGKPEGPPPQGGNQS 131

Query: 150 RGPAAAFAVEPGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGP 209
           +GP        G   +  N S     R G   G PP      + P   P  P  P  +G 
Sbjct: 132 QGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGG 191

Query: 210 GRLLTREPPSRKLPP--PLPLCRSRWVLAPPPPPAPPGP-----NAAAHPPLRPPRARLQ 262
            +  ++ PP R   P  P P   ++    PP P  P GP     N    PP  P + +  
Sbjct: 192 NQ--SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGP 249

Query: 263 DPVD---PER--CPGGPSRGPGHGTHAHSELP 289
            P +   P+R   PG P   P  G +    LP
Sbjct: 250 PPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLP 281



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 50/195 (25%), Positives = 62/195 (31%), Gaps = 7/195 (3%)

Query: 90  PEPGRGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGG 149
           P PG+       GG       P P  P+      G    G   R  G   G  P+     
Sbjct: 52  PPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPR-PGKPEGQPPQGGNQS 110

Query: 150 RGPAAAFAVEPGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGP 209
           +GP        G   +  N S     R G   G PP      + P   P  P  P  +G 
Sbjct: 111 QGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGG 170

Query: 210 GRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAPPGP-----NAAAHPPLRPPRARLQDP 264
            +     P   K   P P   ++    PP P  P GP     N +  PP RP +     P
Sbjct: 171 NQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPE-GPP 229

Query: 265 VDPERCPGGPSRGPG 279
                 P GP   PG
Sbjct: 230 SQGGNKPQGPPPHPG 244


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 46/147 (31%), Positives = 55/147 (37%), Gaps = 15/147 (10%)

Query: 137 GSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYF 196
           G++  +P R P G   AAA A  P T   P              P  P A+  P R P  
Sbjct: 105 GATPPAPPRAPRGAPAAAAAAAPPPTPAPPP-------------PPAPVAAAAPARAPRA 151

Query: 197 APPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPP--APPGPNAAAHPPL 254
           A      P S GP +   R   +  L  P P   +   +APP  P  APP   AA  PPL
Sbjct: 152 AAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPL 211

Query: 255 RPPRARLQDPVDPERCPGGPSRGPGHG 281
            PP      P   +  P  P   P  G
Sbjct: 212 PPPPQPPAPPQQQQPPPPQPQPPPEGG 238



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 47/147 (31%), Positives = 56/147 (38%), Gaps = 18/147 (12%)

Query: 107 TPQSPGPCAPQ---ALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTG 163
           TP +P P AP+   A A+   P             + A+P R P     AA     PG  
Sbjct: 107 TPPAP-PRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPA 165

Query: 164 QR-PRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKL 222
           Q  PR      A R+  +   PPA   P   P  APP    P    P  +  REPP    
Sbjct: 166 QPGPR------AQRAAPLAAPPPAPAAP---PAVAPPA--GPRRAPPPAVAAREPPLP-- 212

Query: 223 PPPLPLCRSRWVLAPPPPPAPPGPNAA 249
           PPP P    +    PPP P PP    A
Sbjct: 213 PPPQPPAPPQQQQPPPPQPQPPPEGGA 239



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 38/115 (33%), Positives = 42/115 (36%), Gaps = 11/115 (9%)

Query: 167 RNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPL 226
           RN +  Q  R G  P  PP +  P   P  A      PT   P       P +   P   
Sbjct: 94  RNAARVQPPRRGATPPAPPRA--PRGAPAAAAAAAPPPTPAPPP---PPAPVAAAAPARA 148

Query: 227 PLCRSRWVLAPPPP-PAPPGPNAAAHPPLR--PPRARLQDPVDPERCPGGPSRGP 278
           P   +    APP P PA PGP A    PL   PP       V P   P GP R P
Sbjct: 149 PRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAP---PAGPRRAP 200



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 33/90 (36%), Positives = 35/90 (38%), Gaps = 15/90 (16%)

Query: 216 EPPSRKLPPPLPLCRSRWV------LAPPPPPAPPGPNA--AAHPPLRPPRARLQDPVDP 267
           +PP R   PP P    R         APPP PAPP P A  AA  P R PRA       P
Sbjct: 100 QPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAP 159

Query: 268 ERCPGGPSRGPGH-GTHAHSELPTCTRLPS 296
                 PS GP   G  A    P     P+
Sbjct: 160 ------PSPGPAQPGPRAQRAAPLAAPPPA 183


>gi|169162152 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 520

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 67/223 (30%), Positives = 83/223 (37%), Gaps = 30/223 (13%)

Query: 83  GRAARGFPEPG-RGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGA 141
           GR+    P  G R GKT +W  G G+  +P P    A   L  P     R     G   A
Sbjct: 108 GRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSP-----REPTPPGRLSA 162

Query: 142 SPRRLPGGRGPAAAFAVEP--GTGQRPRNTSLAQA---------SRSGTVPGLPPASLQP 190
            PR  P  +      A  P  G+G+ PR     QA         +  G+V  L P S +P
Sbjct: 163 PPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLP-SAKP 221

Query: 191 LRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWV--------LAPPPPPA 242
            R P  AP    +  +   GR     P +R      PL R            LA  PPP 
Sbjct: 222 ARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPL 281

Query: 243 PPGPNAAAHPPLRPPRARLQDP---VDPERCPGGPSRGP-GHG 281
            P   +A+ P L  P A  + P     P RC     R P GHG
Sbjct: 282 QPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHG 324



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 57/209 (27%), Positives = 69/209 (33%), Gaps = 44/209 (21%)

Query: 68  GSPTRDQEIRAGSSCG-RAARGFPEPGRGGKTQEWGGGTGTPQSP-GPCAPQALASLLGP 125
           G P      R G   G R  RG  E    G+ Q  G   G+P  P GP AP       G 
Sbjct: 324 GLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQ--GCALGSPPIPAGPAAP----GRAGE 377

Query: 126 GKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTVPGLPP 185
            +A  + R +GG  G SPR    G G      V  G   R R +S        T  G  P
Sbjct: 378 RRAARQWRKRGGGPGVSPREGAQGEG------VRGGVTPRARGSSTCLRPSPATWQGGAP 431

Query: 186 -----ASLQPLRVPYFAP---PGPH---DPTSRGPGRLLTREPPSRKLPPPLPL------ 228
                A+   L  P       PG H   +PT        T+ P   +  P  P       
Sbjct: 432 YRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYL 491

Query: 229 -------------CRSRWVLAPPPPPAPP 244
                         RS +  +PP P  PP
Sbjct: 492 DRESGLGSVNSHPSRSPYNWSPPSPSVPP 520



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 42/134 (31%), Positives = 50/134 (37%), Gaps = 26/134 (19%)

Query: 147 PGGRGPAAAFAVEPGTGQRPRNTSLAQASRSG-------TVPGL---PPASLQPLRVPYF 196
           P  RG   A      TG +P       A R+G       T PG    P  SL P +    
Sbjct: 51  PRARGVEVASGRTRWTGPQPL-VDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGR 109

Query: 197 APPGPH-DPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAP--PPPP----APP--GPN 247
           + P P    T RG          S   P P  L   RW+ +P  P PP    APP  GP+
Sbjct: 110 SKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPH 169

Query: 248 ------AAAHPPLR 255
                  +AHPP R
Sbjct: 170 PQSFRRPSAHPPGR 183


>gi|169161145 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 520

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 67/223 (30%), Positives = 83/223 (37%), Gaps = 30/223 (13%)

Query: 83  GRAARGFPEPG-RGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGA 141
           GR+    P  G R GKT +W  G G+  +P P    A   L  P     R     G   A
Sbjct: 108 GRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSP-----REPTPPGRLSA 162

Query: 142 SPRRLPGGRGPAAAFAVEP--GTGQRPRNTSLAQA---------SRSGTVPGLPPASLQP 190
            PR  P  +      A  P  G+G+ PR     QA         +  G+V  L P S +P
Sbjct: 163 PPRHGPHPQSFRRPSAHPPGRGSGRVPRGQPEQQAWEQRSSHFLAPEGSVASLLP-SAKP 221

Query: 191 LRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWV--------LAPPPPPA 242
            R P  AP    +  +   GR     P +R      PL R            LA  PPP 
Sbjct: 222 ARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPL 281

Query: 243 PPGPNAAAHPPLRPPRARLQDP---VDPERCPGGPSRGP-GHG 281
            P   +A+ P L  P A  + P     P RC     R P GHG
Sbjct: 282 QPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHG 324



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 57/209 (27%), Positives = 69/209 (33%), Gaps = 44/209 (21%)

Query: 68  GSPTRDQEIRAGSSCG-RAARGFPEPGRGGKTQEWGGGTGTPQSP-GPCAPQALASLLGP 125
           G P      R G   G R  RG  E    G+ Q  G   G+P  P GP AP       G 
Sbjct: 324 GLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQ--GCALGSPPIPAGPAAP----GRAGE 377

Query: 126 GKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTVPGLPP 185
            +A  + R +GG  G SPR    G G      V  G   R R +S        T  G  P
Sbjct: 378 RRAARQWRKRGGGPGVSPREGAQGEG------VRGGVTPRARGSSTCLRPSPATWQGGAP 431

Query: 186 -----ASLQPLRVPYFAP---PGPH---DPTSRGPGRLLTREPPSRKLPPPLPL------ 228
                A+   L  P       PG H   +PT        T+ P   +  P  P       
Sbjct: 432 YRAIFAAGPRLSAPSAEAEEVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYL 491

Query: 229 -------------CRSRWVLAPPPPPAPP 244
                         RS +  +PP P  PP
Sbjct: 492 DRESGLGSVNSHPSRSPYNWSPPSPSVPP 520



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 42/134 (31%), Positives = 50/134 (37%), Gaps = 26/134 (19%)

Query: 147 PGGRGPAAAFAVEPGTGQRPRNTSLAQASRSG-------TVPGL---PPASLQPLRVPYF 196
           P  RG   A      TG +P       A R+G       T PG    P  SL P +    
Sbjct: 51  PRARGVEVASGRTRWTGPQPL-VDTPPARRAGELCEAPQTAPGFHFQPFLSLSPHQERGR 109

Query: 197 APPGPH-DPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAP--PPPP----APP--GPN 247
           + P P    T RG          S   P P  L   RW+ +P  P PP    APP  GP+
Sbjct: 110 SKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREPTPPGRLSAPPRHGPH 169

Query: 248 ------AAAHPPLR 255
                  +AHPP R
Sbjct: 170 PQSFRRPSAHPPGR 183


>gi|110431370 espin [Homo sapiens]
          Length = 854

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 43/127 (33%), Positives = 52/127 (40%), Gaps = 16/127 (12%)

Query: 131 RARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTVPGLPPASLQP 190
           RA  +  S+G   R+L  GR P    A  PG           Q +R+G  P L PA+   
Sbjct: 508 RAFSKQPSTGDYYRQL--GRCPGETLAARPGMAHS-EEVRARQPARAGC-PRLGPAARGS 563

Query: 191 LRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAAA 250
           L  P   P     P +  P         SR+LPPP            PPPP PP P AA+
Sbjct: 564 LEGPSAPPQAALLPGNHVPNGCAADPKASRELPPP------------PPPPPPPLPEAAS 611

Query: 251 HPPLRPP 257
            PP  PP
Sbjct: 612 SPPPAPP 618



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 29/96 (30%), Positives = 33/96 (34%), Gaps = 11/96 (11%)

Query: 168 NTSLAQASRSGTVPGLPPASLQPLRVP----YFAPPGPHDPTSRGPGRLLTREPPSRKLP 223
           N     +S S      PP  L   R      Y     P     RG     T  PP    P
Sbjct: 379 NYDSCSSSHSSIKGQHPPCGLSSARAADIQSYMDMLNPELGLPRGTIGKPTPPPPPPSFP 438

Query: 224 PPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPPRA 259
           PP P   ++    PPPPP  P P     PP+ P  A
Sbjct: 439 PPPPPPGTQ---LPPPPPGYPAPK----PPVGPQAA 467



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 27/85 (31%), Positives = 32/85 (37%), Gaps = 10/85 (11%)

Query: 200 GPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPPRA 259
           G H P      R    +     L P L L R   +  P PPP PP    +  PP  PP  
Sbjct: 392 GQHPPCGLSSARAADIQSYMDMLNPELGLPRGT-IGKPTPPPPPP----SFPPPPPPPGT 446

Query: 260 RLQDPVDPERCPGGPSRGPGHGTHA 284
           +L  P      PG P+  P  G  A
Sbjct: 447 QLPPPP-----PGYPAPKPPVGPQA 466


>gi|40353727 synaptopodin isoform A [Homo sapiens]
          Length = 903

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 58/198 (29%), Positives = 73/198 (36%), Gaps = 31/198 (15%)

Query: 103 GGTGTPQSPG----PCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFA- 157
           GG  +P SP     P A QA         AG  A+ +  S   SP   PG   P ++   
Sbjct: 642 GGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDG 701

Query: 158 -VEPGTGQRPRNTSLAQASRSGTVPGLPPA----SLQPLRVPYFAPPGPHDPTSRGPGRL 212
            V PG  +  R +S++        P + P+    S+ PLR     P     P SR    L
Sbjct: 702 WVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLR-----PETEARPPSRQLQAL 756

Query: 213 LTRE-----------PPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPPRARL 261
           L R            P S     P P    R    PPPPP PP P   +  P RP  A +
Sbjct: 757 LARNIINAARRKSASPRSAGAENPRPFSPPR-APPPPPPPPPPPPRMRSPQPARPGSAAV 815

Query: 262 QD----PVDPERCPGGPS 275
                 P+     P GPS
Sbjct: 816 PGAAFAPIPRSPLPAGPS 833


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 56/217 (25%), Positives = 78/217 (35%), Gaps = 30/217 (13%)

Query: 58  PGTQRGVREVGSPTRDQEIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQSPGPCAPQ 117
           PGT +   +   P +    + GS    +     +PG     Q  G G    Q PGP  P 
Sbjct: 356 PGTTKPPAQPLGPAKPPAQQTGSEKPSSE----QPGPKALAQPPGVGKTPAQQPGPAKPP 411

Query: 118 ALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRP-RNTSLAQASR 176
                    + G    L       SP + PG   P      +PG G+ P +     + S 
Sbjct: 412 TQ-------QVGTPKPLAQQPGLQSPAKAPG---PTKTPVQQPGPGKIPAQQAGPGKTSA 461

Query: 177 SGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPG--RLLTREPPSRKLPPPLPLCRSRWV 234
             T P  PP+ L     P    PGP  P  + PG  +  +++P S K PP  P       
Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQP------- 514

Query: 235 LAPPPPPAPPGPNAAAHPPLRP----PRARLQDPVDP 267
              P  P+P  P +   P  +P    P A+   P  P
Sbjct: 515 --GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKP 549



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 48/190 (25%), Positives = 69/190 (36%), Gaps = 21/190 (11%)

Query: 104 GTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTG 163
           GTG P       PQ   + L   +   R + +           P    P+     +P  G
Sbjct: 253 GTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPG 312

Query: 164 QRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLP 223
           + P      + S+ G  P  PPA    L  P    PG   P  + PG   T +PP++ L 
Sbjct: 313 KPPAQQPGHEKSQPG--PAKPPAQPSGLTKPLAQQPGTVKPPVQPPG---TTKPPAQPLG 367

Query: 224 PPLPLCRSRWVLAPPPPPAPPGPNAAAHP------------PLRPPRARLQDPVDPERCP 271
           P  P  +     +  P    PGP A A P            P +PP  ++  P    + P
Sbjct: 368 PAKPPAQQTG--SEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQP 425

Query: 272 G--GPSRGPG 279
           G   P++ PG
Sbjct: 426 GLQSPAKAPG 435



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 52/194 (26%), Positives = 67/194 (34%), Gaps = 14/194 (7%)

Query: 104 GTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGAS-----PRRLPGGRGPAAAFAV 158
           GT  P    P   +  A  LGP K   +   Q GS   S     P+ L    G     A 
Sbjct: 347 GTVKPPVQPPGTTKPPAQPLGPAKPPAQ---QTGSEKPSSEQPGPKALAQPPGVGKTPAQ 403

Query: 159 EPGTGQRPRNTSLAQASRSGTVPGL--PPASLQPLRVPYFAP-PGPHDPTSRGPGRLLTR 215
           +PG   +P    +         PGL  P  +  P + P   P PG       GPG+   +
Sbjct: 404 QPGPA-KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462

Query: 216 EPPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPPRARLQDPVDPERCPGGPS 275
           +    K P  LP         P P   PP    +A PP + P +    P  P   P  PS
Sbjct: 463 QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG--PAKPS 520

Query: 276 RGPGHGTHAHSELP 289
                 T   S+ P
Sbjct: 521 PQQPGSTKPPSQQP 534



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 52/208 (25%), Positives = 74/208 (35%), Gaps = 40/208 (19%)

Query: 103 GGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGT 162
           G +  P  P P  P       G   A      +     A P   P G       A +PGT
Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGL--TKPLAQQPGT 348

Query: 163 GQ---RPRNTSLAQASRSGTVPGLPPA---------SLQPLRVPYFAPPGPHDPTSRGPG 210
            +   +P  T+   A   G  P  PPA         S QP       PPG     ++ PG
Sbjct: 349 VKPPVQPPGTTKPPAQPLG--PAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPG 406

Query: 211 RLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAP-------PGP-------------NAAA 250
                +PP++++  P PL +   + +P   P P       PGP             +A  
Sbjct: 407 ---PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463

Query: 251 HPPLRPPRARLQDPVDPERCPGGPSRGP 278
             P +PP ++L  P  P     GP++ P
Sbjct: 464 TGPTKPP-SQLPGPAKPPPQQPGPAKPP 490



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 26/74 (35%), Positives = 30/74 (40%), Gaps = 16/74 (21%)

Query: 185  PASLQPLRVPYFAP-PGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAP 243
            PAS  P   P  +  P    P  R     ++ +PP    PPP           PPPPP P
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPP----PPP-----------PPPPPPP 2416

Query: 244  PGPNAAAHPPLRPP 257
            P P     PPL PP
Sbjct: 2417 PPPPPPPPPPLPPP 2430



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 21/114 (18%)

Query: 173  QASRSGTVPGLPPASL------QPLRVPYFAPP---GPHDPTSRGPGRLLTREPPSRKLP 223
            ++S S TV   PP+S+      + L   YF      G   P S+ P    +  P    LP
Sbjct: 2332 KSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLP----SGSPSVSSLP 2387

Query: 224  P-PLPLCRSRWV-------LAPPPPPAPPGPNAAAHPPLRPPRARLQDPVDPER 269
              P P  RS  +         PPPPP PP P     PP  PP    +  + P++
Sbjct: 2388 AKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKK 2441



 Score = 29.6 bits (65), Expect = 3.7
 Identities = 26/99 (26%), Positives = 35/99 (35%), Gaps = 6/99 (6%)

Query: 176  RSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRS--RW 233
            +    P  PP S  P +    APP    P    P +  T+ P + KL P      +  R 
Sbjct: 965  KQAPAPSQPPTSQGPPKSTGQAPPA---PAKSIPVKKETKAPAAEKLEPKAEQAPTVKRT 1021

Query: 234  VLAPPPPPAPPGPNAAAHPPLRPPRARLQDPVDPE-RCP 271
                 PPP     +  A P       +L+    PE  CP
Sbjct: 1022 ETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 56/217 (25%), Positives = 78/217 (35%), Gaps = 30/217 (13%)

Query: 58  PGTQRGVREVGSPTRDQEIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQSPGPCAPQ 117
           PGT +   +   P +    + GS    +     +PG     Q  G G    Q PGP  P 
Sbjct: 356 PGTTKPPAQPLGPAKPPAQQTGSEKPSSE----QPGPKALAQPPGVGKTPAQQPGPAKPP 411

Query: 118 ALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRP-RNTSLAQASR 176
                    + G    L       SP + PG   P      +PG G+ P +     + S 
Sbjct: 412 TQ-------QVGTPKPLAQQPGLQSPAKAPG---PTKTPVQQPGPGKIPAQQAGPGKTSA 461

Query: 177 SGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPG--RLLTREPPSRKLPPPLPLCRSRWV 234
             T P  PP+ L     P    PGP  P  + PG  +  +++P S K PP  P       
Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQP------- 514

Query: 235 LAPPPPPAPPGPNAAAHPPLRP----PRARLQDPVDP 267
              P  P+P  P +   P  +P    P A+   P  P
Sbjct: 515 --GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKP 549



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 48/190 (25%), Positives = 69/190 (36%), Gaps = 21/190 (11%)

Query: 104 GTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTG 163
           GTG P       PQ   + L   +   R + +           P    P+     +P  G
Sbjct: 253 GTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPG 312

Query: 164 QRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLP 223
           + P      + S+ G  P  PPA    L  P    PG   P  + PG   T +PP++ L 
Sbjct: 313 KPPAQQPGHEKSQPG--PAKPPAQPSGLTKPLAQQPGTVKPPVQPPG---TTKPPAQPLG 367

Query: 224 PPLPLCRSRWVLAPPPPPAPPGPNAAAHP------------PLRPPRARLQDPVDPERCP 271
           P  P  +     +  P    PGP A A P            P +PP  ++  P    + P
Sbjct: 368 PAKPPAQQTG--SEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQP 425

Query: 272 G--GPSRGPG 279
           G   P++ PG
Sbjct: 426 GLQSPAKAPG 435



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 52/194 (26%), Positives = 67/194 (34%), Gaps = 14/194 (7%)

Query: 104 GTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGAS-----PRRLPGGRGPAAAFAV 158
           GT  P    P   +  A  LGP K   +   Q GS   S     P+ L    G     A 
Sbjct: 347 GTVKPPVQPPGTTKPPAQPLGPAKPPAQ---QTGSEKPSSEQPGPKALAQPPGVGKTPAQ 403

Query: 159 EPGTGQRPRNTSLAQASRSGTVPGL--PPASLQPLRVPYFAP-PGPHDPTSRGPGRLLTR 215
           +PG   +P    +         PGL  P  +  P + P   P PG       GPG+   +
Sbjct: 404 QPGPA-KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462

Query: 216 EPPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPPRARLQDPVDPERCPGGPS 275
           +    K P  LP         P P   PP    +A PP + P +    P  P   P  PS
Sbjct: 463 QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG--PAKPS 520

Query: 276 RGPGHGTHAHSELP 289
                 T   S+ P
Sbjct: 521 PQQPGSTKPPSQQP 534



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 52/208 (25%), Positives = 74/208 (35%), Gaps = 40/208 (19%)

Query: 103 GGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGT 162
           G +  P  P P  P       G   A      +     A P   P G       A +PGT
Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGL--TKPLAQQPGT 348

Query: 163 GQ---RPRNTSLAQASRSGTVPGLPPA---------SLQPLRVPYFAPPGPHDPTSRGPG 210
            +   +P  T+   A   G  P  PPA         S QP       PPG     ++ PG
Sbjct: 349 VKPPVQPPGTTKPPAQPLG--PAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPG 406

Query: 211 RLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAP-------PGP-------------NAAA 250
                +PP++++  P PL +   + +P   P P       PGP             +A  
Sbjct: 407 ---PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463

Query: 251 HPPLRPPRARLQDPVDPERCPGGPSRGP 278
             P +PP ++L  P  P     GP++ P
Sbjct: 464 TGPTKPP-SQLPGPAKPPPQQPGPAKPP 490



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 26/74 (35%), Positives = 30/74 (40%), Gaps = 16/74 (21%)

Query: 185  PASLQPLRVPYFAP-PGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAP 243
            PAS  P   P  +  P    P  R     ++ +PP    PPP           PPPPP P
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPP----PPP-----------PPPPPPP 2416

Query: 244  PGPNAAAHPPLRPP 257
            P P     PPL PP
Sbjct: 2417 PPPPPPPPPPLPPP 2430



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 21/114 (18%)

Query: 173  QASRSGTVPGLPPASL------QPLRVPYFAPP---GPHDPTSRGPGRLLTREPPSRKLP 223
            ++S S TV   PP+S+      + L   YF      G   P S+ P    +  P    LP
Sbjct: 2332 KSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLP----SGSPSVSSLP 2387

Query: 224  P-PLPLCRSRWV-------LAPPPPPAPPGPNAAAHPPLRPPRARLQDPVDPER 269
              P P  RS  +         PPPPP PP P     PP  PP    +  + P++
Sbjct: 2388 AKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKK 2441



 Score = 29.6 bits (65), Expect = 3.7
 Identities = 26/99 (26%), Positives = 35/99 (35%), Gaps = 6/99 (6%)

Query: 176  RSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRS--RW 233
            +    P  PP S  P +    APP    P    P +  T+ P + KL P      +  R 
Sbjct: 965  KQAPAPSQPPTSQGPPKSTGQAPPA---PAKSIPVKKETKAPAAEKLEPKAEQAPTVKRT 1021

Query: 234  VLAPPPPPAPPGPNAAAHPPLRPPRARLQDPVDPE-RCP 271
                 PPP     +  A P       +L+    PE  CP
Sbjct: 1022 ETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 62/210 (29%), Positives = 76/210 (36%), Gaps = 35/210 (16%)

Query: 51   QRGRNGAPGTQRGVREVGSPTRDQEIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQS 110
            + GR GAPG +      GSP RD     GS   +  RG  E G  G      G  G P +
Sbjct: 1011 ESGREGAPGAE------GSPGRD-----GSPGAKGDRG--ETGPAGPP----GAPGAPGA 1053

Query: 111  PGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTS 170
            PGP  P         GK+G R    G +  A P    G RGPA         G+      
Sbjct: 1054 PGPVGPA--------GKSGDRGET-GPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGD 1104

Query: 171  LAQASRSGTV-----PGLPPASLQPLRVPYFAPPGPHDP--TSRGPGRLLTREPPSRKLP 223
                   G       PG P +  +        P GP  P  ++  PG+      P   + 
Sbjct: 1105 RGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPG-PIG 1163

Query: 224  PPLPLCRSRWVLAPPPPPAPPGPNAAAHPP 253
            PP P  R+     P  PP PPGP     PP
Sbjct: 1164 PPGPRGRTGDA-GPVGPPGPPGPPGPPGPP 1192



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 78/265 (29%), Positives = 92/265 (34%), Gaps = 51/265 (19%)

Query: 52  RGRNGAPGTQRGVREVGSPTRDQEIRAGSSCG----RAARGFPEPGRGGKTQEWGGGTGT 107
           RG NGAPG      + G+P       A    G    R A G P P +G +     G  G 
Sbjct: 697 RGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGP-KGDRGD--AGPKGA 753

Query: 108 PQSPGPCAPQALASLLGP-GKAGCRA-RLQGGSSG-ASP---RRLPGGRGPA-----AAF 156
             SPG    + L   +GP G AG    + + G SG A P   R  PG RG       A F
Sbjct: 754 DGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGF 813

Query: 157 AVEPGT-GQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPT---------- 205
           A  PG  GQ         A   G     PP    P       PPGP              
Sbjct: 814 AGPPGADGQPGAKGEPGDAGAKGDAG--PPGPAGPA-----GPPGPIGNVGAPGAKGARG 866

Query: 206 SRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAP------PGPNAAAHPPLRPPRA 259
           S GP         + ++ PP P   +     PP PP P       GP     P  RP   
Sbjct: 867 SAGPPGATGFPGAAGRVGPPGPSGNA----GPPGPPGPAGKEGGKGPRGETGPAGRPGEV 922

Query: 260 RLQDPVDP---ERCPG--GPSRGPG 279
               P  P   +  PG  GP+  PG
Sbjct: 923 GPPGPPGPAGEKGSPGADGPAGAPG 947



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 75/266 (28%), Positives = 82/266 (30%), Gaps = 31/266 (11%)

Query: 53  GRNGAPGTQRGVREVGSPTRDQEIRAGSSCGRAARGFP-EPGRGGKTQEWG-----GGTG 106
           G +GA G        G P    E  A    G   RG P E GR G     G     G TG
Sbjct: 272 GLDGAKGDAGPAGPKGEPGSPGENGAPGQMG--PRGLPGERGRPGAPGPAGARGNDGATG 329

Query: 107 TPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGP-----AAAFAVEPG 161
               PGP  P       G   A   A  QG      P+ + G  GP     AA  A  PG
Sbjct: 330 AAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPG 389

Query: 162 TGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHD-------PTSRGPGRLLT 214
              +P       A      PG P A           PPGP         P S+G      
Sbjct: 390 ADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKG 449

Query: 215 REPPSRKLPPPLPLCR--SRWVLAPPPP---PAPPGPNAAAHPPLRPPRARLQDPVDP-- 267
              P     PP P      R     P P   P PPG          P    +  P  P  
Sbjct: 450 EPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAG 509

Query: 268 ER---CPGGPSRGPGH-GTHAHSELP 289
           ER    P GP   PG  G    + LP
Sbjct: 510 ERGSPGPAGPKGSPGEAGRPGEAGLP 535



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 56/200 (28%), Positives = 62/200 (31%), Gaps = 24/200 (12%)

Query: 53   GRNGAPGTQRGVREVGSPTRDQEIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQSPG 112
            GR G PG        G P       AG   G+  RG  E G  G+     G  G P  PG
Sbjct: 881  GRVGPPGPSGNAGPPGPPGP-----AGKEGGKGPRG--ETGPAGRP----GEVGPPGPPG 929

Query: 113  PCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTSLA 172
            P   +      GP  A      QG +       LPG RG    F   PG    P     +
Sbjct: 930  PAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRG-ERGFPGLPGPSGEPGKQGPS 988

Query: 173  QASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSR 232
             AS     PG       P+  P  A P         PG       P R   P       R
Sbjct: 989  GASGERGPPG-------PMGPPGLAGPPGESGREGAPG---AEGSPGRDGSPGAK--GDR 1036

Query: 233  WVLAPPPPPAPPGPNAAAHP 252
                P  PP  PG   A  P
Sbjct: 1037 GETGPAGPPGAPGAPGAPGP 1056



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 66/232 (28%), Positives = 76/232 (32%), Gaps = 72/232 (31%)

Query: 51  QRGRNGAPGTQRGVREVGSPTRDQEIRAGSSCGRAARGFP-EPGRGGKTQEWG--GGTGT 107
           +RG  G  G +    E G P       AG    +   G P  PG  GKT   G  G  G 
Sbjct: 510 ERGSPGPAGPKGSPGEAGRPGE-----AGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGR 564

Query: 108 PQSPGPCAPQALASLLG----------PGKAGCR-----------------ARLQGGSSG 140
           P  PGP   +  A ++G          PGKAG R                 A  QG    
Sbjct: 565 PGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGP 624

Query: 141 ASPRRLPGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTVPGLP-PASLQPLRVPYFAPP 199
           A P    G +GPA +    PG                    GLP PA           PP
Sbjct: 625 AGPAGERGEQGPAGS----PG------------------FQGLPGPA----------GPP 652

Query: 200 G-PHDPTSRG-PGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAA 249
           G    P  +G PG L    P   +     P    R V  PP P  P G N A
Sbjct: 653 GEAGKPGEQGVPGDLGAPGPSGARGERGFP--GERGVQGPPGPAGPRGANGA 702



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 40/152 (26%), Positives = 49/152 (32%), Gaps = 23/152 (15%)

Query: 137 GSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYF 196
           GS   + +   G  GP         TG R          R G +PG P     P      
Sbjct: 98  GSESPTDQETTGVEGPKG------DTGPRGPRGPAGPPGRDG-IPGQPGLPGPP------ 144

Query: 197 APPGPHDPTSRG----PGRLLTREPPSR---KLPPPLPLCRSRWVLAPPPPPAPPGPNAA 249
            PPGP  P   G    P      +  S     +P P+     R +   P PP  PGP   
Sbjct: 145 GPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGL---PGPPGAPGPQGF 201

Query: 250 AHPPLRPPRARLQDPVDPERCPGGPSRGPGHG 281
             PP  P       P+ P   PG P +    G
Sbjct: 202 QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDG 233



 Score = 37.0 bits (84), Expect = 0.023
 Identities = 56/205 (27%), Positives = 67/205 (32%), Gaps = 44/205 (21%)

Query: 53  GRNGAPGTQRGVREVGSPTRDQEIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQSPG 112
           G  G PG Q    ++G+P        G S  R  RGFP            G  G    PG
Sbjct: 653 GEAGKPGEQGVPGDLGAP--------GPSGARGERGFP------------GERGVQGPPG 692

Query: 113 PCAPQALASLLGPGKAGCRARLQG--GSSGASPRR-LPGGRGPAAAFAVEPGTGQRPRNT 169
           P  P+      G   A   A   G  GS GA   + +PG RG A     +   G      
Sbjct: 693 PAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKG 752

Query: 170 SLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHD-PTSRGPGRLLTREPPSRKLPPPLPL 228
           +     + G V GL              PPGP   P  +G         PS    P    
Sbjct: 753 ADGSPGKDG-VRGLTGP---------IGPPGPAGAPGDKG------ESGPSGPAGPT--- 793

Query: 229 CRSRWVLAPPPPPAPPGPNAAAHPP 253
             +R        P PPGP   A PP
Sbjct: 794 -GARGAPGDRGEPGPPGPAGFAGPP 817



 Score = 36.6 bits (83), Expect = 0.030
 Identities = 54/211 (25%), Positives = 69/211 (32%), Gaps = 28/211 (13%)

Query: 75  EIRAGSSCGRAARGFPEPGRGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARL 134
           E+  G  C     G   P      QE  G  G     GP  P+  A    PG+ G   + 
Sbjct: 85  EVPEGECCPVCPDGSESP----TDQETTGVEGPKGDTGPRGPRGPAG--PPGRDGIPGQ- 137

Query: 135 QGGSSGASPRRLPGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVP 194
            G      P   PG  G    FA +   G   ++T         +VPG P     P  +P
Sbjct: 138 PGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTG------GISVPG-PMGPSGPRGLP 190

Query: 195 YFAPPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAAAHPPL 254
              PPG        PG    + PP     P      +   + P  PP PPG N       
Sbjct: 191 --GPPG-------APGPQGFQGPPGEPGEPG-----ASGPMGPRGPPGPPGKNGDDGEAG 236

Query: 255 RPPRARLQDPVDPERCPGGPSRGPGHGTHAH 285
           +P R   + P  P+   G P      G   H
Sbjct: 237 KPGRPGERGPPGPQGARGLPGTAGLPGMKGH 267



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 70/229 (30%), Positives = 81/229 (35%), Gaps = 41/229 (17%)

Query: 53   GRNGAPGTQRGVREVGSPTRDQEIRAGSSCGRAARGFPEPGRGGKTQEWG--GGTGTPQS 110
            G  GAPG  RG  E G P       AG +    A G  +PG  G+  + G  G  G P  
Sbjct: 794  GARGAPG-DRG--EPGPPGP-----AGFAGPPGADG--QPGAKGEPGDAGAKGDAGPPGP 843

Query: 111  PGPCAPQALASLLG-PGKAGCRARL----QGGSSGASPRRLPGGRGPAAAFAVEPGT--- 162
             GP  P      +G PG  G R         G  GA+ R  P G    A     PG    
Sbjct: 844  AGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGK 903

Query: 163  --GQRPRNTSLAQASRSGTV--PGLP--------PASLQPLRVPYFAPPGPHDPTS-RG- 208
              G+ PR  +   A R G V  PG P        P +  P   P    PGP      RG 
Sbjct: 904  EGGKGPRGET-GPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAP--GTPGPQGIAGQRGV 960

Query: 209  ---PGRLLTREPPSRKLPPPLPLCRS-RWVLAPPPPPAPPGPNAAAHPP 253
               PG+   R  P    P   P  +          PP P GP   A PP
Sbjct: 961  VGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPP 1009


>gi|134244285 Notch homolog 3 [Homo sapiens]
          Length = 2321

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 69/221 (31%), Positives = 86/221 (38%), Gaps = 37/221 (16%)

Query: 105  TGTPQSPGP-------CAPQALASLLGPGKAGCR-ARLQGGSSGASPRRLPGGRGPAAAF 156
            +G    PGP       C P A    L   ++G + +R   G +G  P+  P GRG     
Sbjct: 2028 SGPRSPPGPHGLGPLLCPPGAFLPGLKAAQSGSKKSRRPPGKAGLGPQG-PRGRGKKLTL 2086

Query: 157  AVEPGTGQRPRNTSLAQASRSGTVPGLPPASLQ--PLRVPYFAPPGPHDPTSR--GPGRL 212
            A            S   +  S    G PPAS    PL  PY A        ++  GPGR 
Sbjct: 2087 ACPGPLADSSVTLSPVDSLDSPRPFGGPPASPGGFPLEGPYAAATATAVSLAQLGGPGRA 2146

Query: 213  -LTREPPSRKL-------PPPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPPRARLQ-- 262
             L R+PP   +       P  +PL  +R      PPPAPPGP+     PL P    L   
Sbjct: 2147 GLGRQPPGGCVLSLGLLNPVAVPLDWARL-----PPPAPPGPSFLL--PLAPGPQLLNPG 2199

Query: 263  DPVDPERCPGGPSRGPGHGTH-----AHSELPTC--TRLPS 296
             PV P+  P      PGHG       AHS  P     R+PS
Sbjct: 2200 TPVSPQERPPPYLAVPGHGEEYPAAGAHSSPPKARFLRVPS 2240



 Score = 32.0 bits (71), Expect = 0.74
 Identities = 45/170 (26%), Positives = 55/170 (32%), Gaps = 32/170 (18%)

Query: 90   PEPGRGGKTQEWGGGTGTPQSPGPCAPQALASLLGPGKAGCRARLQGG--------SSGA 141
            P P  G      G     P +       +LA L GPG+AG   +  GG        +  A
Sbjct: 2108 PRPFGGPPASPGGFPLEGPYAAATATAVSLAQLGGPGRAGLGRQPPGGCVLSLGLLNPVA 2167

Query: 142  SP---RRLPGGRGPAAAFAVEPGTGQRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAP 198
             P    RLP    P  +F +    G +  N            PG  P S Q    PY A 
Sbjct: 2168 VPLDWARLPPPAPPGPSFLLPLAPGPQLLN------------PG-TPVSPQERPPPYLAV 2214

Query: 199  PGPHD------PTSRGPGRLLTREPPSRKLPPPLPLCRSRWVLAPPPPPA 242
            PG  +        S  P     R P       P P     W  A P PP+
Sbjct: 2215 PGHGEEYPAAGAHSSPPKARFLRVPSEHPYLTPSPESPEHW--ASPSPPS 2262


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 63/221 (28%), Positives = 74/221 (33%), Gaps = 45/221 (20%)

Query: 65  REVGSPTRDQEIRAGSSCGRAAR---GFPEPGRGGKTQEWGGGTGTPQSPGPCAPQALAS 121
           R+   PT      A +   RAA    G P P    + +        P + GP    + AS
Sbjct: 162 RDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR--------PPTEGPRKSVSSAS 213

Query: 122 ---LLGPGKAGCRARLQGG----------SSGASPRRLPGGRGPAAAFAVE-PGTGQRPR 167
                 P  A  R    GG          SS A+P   P   GP+A      P    +P+
Sbjct: 214 EHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK 273

Query: 168 NTSL-------AQASRSGTVPGLPPASLQPLRVPYFAPPG----PHDPTSRGPGRLLTRE 216
              L           R    P L P S  PL  P  +P G    P  P       L    
Sbjct: 274 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP--SPSGTKARPVPPPDNAATPLPATL 331

Query: 217 PPSRKLPPPLPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPP 257
           PPS  L  PLPL       APP P APP       PP  PP
Sbjct: 332 PPSPPLATPLPL-------APPSPSAPPSLQTLPSPPATPP 365



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 58/205 (28%), Positives = 68/205 (33%), Gaps = 37/205 (18%)

Query: 105 TGTPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQ 164
           T  PQ+P P A   L     P            S   SP   P  R P    A       
Sbjct: 721 TPPPQAPPPLAAPPLQVPPSPP----------ASPPMSPSATPPPRVPPLLAAPPLQVPP 770

Query: 165 RPRNTSLAQASRSGTVPGLPPA----SLQPLRVPYFAPPG--PHDPTSRGPGRLLTREPP 218
            P   SL  +  +   P  PPA     LQ L  P  + PG  P  P++  P   L   PP
Sbjct: 771 SPP-ASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829

Query: 219 SRKLPPPL--PLCRSRWVLAPPPPPAPPGPNAAAHPPLRPPRARLQ-----------DPV 265
             + PP L  PL +      PP PPA P   A   PP   P   +             P 
Sbjct: 830 --QAPPVLAAPLLQ-----VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 882

Query: 266 DPERCPGGPSRGPGHGTHAHSELPT 290
            P R P     GP    H+ S   T
Sbjct: 883 PPSRSPSSTLSGPDLAGHSSSATST 907



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 49/180 (27%), Positives = 61/180 (33%), Gaps = 21/180 (11%)

Query: 107 TPQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFAVEPGTGQ-- 164
           TP S     PQA  +L  P   G  +      +   P+  P    P       P      
Sbjct: 583 TPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPL 642

Query: 165 RPRNTSLAQASRSGTV-----PGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPPS 219
            P  T   QA  +  V     P  PP S  P++ P+  P  P    S  P    ++ PPS
Sbjct: 643 SPLATPSPQAPNALAVHLLQAPFSPPPS-PPVQAPFSPPASPPVSPSATPP---SQAPPS 698

Query: 220 RKLPPPLPLCRSRWVLAPPPPPA-PPGPNAAAHPPLRPPRARLQDPVDPERCPGGPSRGP 278
              PP         +  PP PPA PP   +A  PP  PP         P   P  P   P
Sbjct: 699 LAAPP---------LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSP 749



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 33/107 (30%), Positives = 38/107 (35%), Gaps = 8/107 (7%)

Query: 180 VPGLPPASLQ----PLRVPYF-APPGPHDPTSRGPGRLLTREPPSRKLPPPLPLCRSRWV 234
           +P L P  LQ    PL  P+   PP P     + P   LT  PP        P  ++   
Sbjct: 538 LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPA 597

Query: 235 LAPPPPPAPPGP---NAAAHPPLRPPRARLQDPVDPERCPGGPSRGP 278
           LA PP    P P     A  PP  PP   L     P   P  P   P
Sbjct: 598 LASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP 644



 Score = 35.4 bits (80), Expect = 0.067
 Identities = 61/231 (26%), Positives = 76/231 (32%), Gaps = 42/231 (18%)

Query: 106 GTPQSPGPCAPQALASLLGPGKAGCR--ARLQGGSSGASPRRLPGGRGPAAAFAVEPGTG 163
           G+P+ P P  P AL  L   G  G +  A   GG  GA+        GP  +       G
Sbjct: 31  GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRS------AG 84

Query: 164 QRPRNTSLAQASRSGTVPGLPPASLQPLRVPYFAPPGPHDPTSRGPGRLLTREPP----S 219
              RN     ASR       PPAS +  R P      P   +S G     TR  P     
Sbjct: 85  TSSRN----PASR-------PPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 133

Query: 220 RKLPPPLPLCRSRWVLAPP--------------PPPAPPGPNAAAHPPLRPPRARLQDPV 265
            ++     + R +   AP               P P  P P  A           L  P 
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193

Query: 266 DPERCPGGPSRGPGHGTHAHSELPTCTRLPSVVFRASGRPYPCFLLCRPSS 316
            P   P  P+ GP     + SE  T    P+    A  RP     L RP+S
Sbjct: 194 -PSARPRPPTEGPRKSVSSASEHSTTEPSPA----ARRRPSAGGGLQRPAS 239



 Score = 35.4 bits (80), Expect = 0.067
 Identities = 50/170 (29%), Positives = 65/170 (38%), Gaps = 25/170 (14%)

Query: 108 PQSPGPCAPQALASLLGPGKAGCRARLQGGSSGASPRRLPGGRGPAAAFA-VEPGTGQRP 166
           P S  P +P   A L  P     +  L   S   SP   P    P  A + +   + Q P
Sbjct: 447 PASTPPDSPPLQAPLSLPASPPLQTSL---SPAVSPLSSPLTIHPLQALSSLASHSPQAP 503

Query: 167 RNTSLA---QASRSGTVPGL--PPASLQ--PLR-VPYFAPPGPHDPTSRGPGRLLTREPP 218
            ++ +    +   S   P L  PPASL   PL  +P  APP    P       L T    
Sbjct: 504 LSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPP----PLQTASAPLTTPHLE 559

Query: 219 SRKLPPPLPLCRSRWVLAPPPP---PAPPGPNAAAHPPLRPPRARLQDPV 265
           +   P P PL       APP P   P P  P++ A PP + P A    P+
Sbjct: 560 TPPCPAPCPL------QAPPSPLTTPPPETPSSIATPPPQAPPALASPPL 603



 Score = 35.0 bits (79), Expect = 0.087
 Identities = 41/125 (32%), Positives = 46/125 (36%), Gaps = 17/125 (13%)

Query: 175 SRSGTVPGLPPASLQ--PLRVPYFAPPGPHDPTSRGPGRLLTREPPSRKLP---PPLPLC 229
           S S T P   P SL   PL+VP   P  P    S  P       PP    P   PPL + 
Sbjct: 686 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP-------PPQAPPPLAAPPLQVP 738

Query: 230 RSRWVLAPPPPPAPPGPNA---AAHPPLR-PPRARLQDPVDPERCPGGPSRGPGHGTHAH 285
            S     P  P A P P      A PPL+ PP      P+ P   P  P   P   T   
Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP-PPQAPPALATPPL 797

Query: 286 SELPT 290
             LP+
Sbjct: 798 QALPS 802



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 35/116 (30%), Positives = 40/116 (34%), Gaps = 18/116 (15%)

Query: 204 PTSRGPGRLLTREPPSRKLPPP-----LPLCRSRWVLAPPPPPAPPGPNAAAHPPLRPPR 258
           P +R PG L  R P S + PPP     L +  +   +   P     G    A  P   PR
Sbjct: 17  PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76

Query: 259 ARLQDPVDPERCPGGPSRGP-------GHGTHAHSELPTCTRLPSVVFRASGRPYP 307
           A       P R  G  SR P       G G  A     T     S   RASG   P
Sbjct: 77  A------GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.138    0.449 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,783,057
Number of Sequences: 37866
Number of extensions: 1685112
Number of successful extensions: 21174
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 489
Number of HSP's successfully gapped in prelim test: 1855
Number of HSP's that attempted gapping in prelim test: 8896
Number of HSP's gapped (non-prelim): 7639
length of query: 316
length of database: 18,247,518
effective HSP length: 102
effective length of query: 214
effective length of database: 14,385,186
effective search space: 3078429804
effective search space used: 3078429804
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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