Guide to the Human Genome
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Search of human proteins with 238550202

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|238550202 tubby like protein 3 isoform 2 [Homo sapiens]
         (501 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|238550202 tubby like protein 3 isoform 2 [Homo sapiens]           1019   0.0  
gi|21536436 tubby like protein 3 isoform 1 [Homo sapiens]             878   0.0  
gi|29826279 tubby isoform b [Homo sapiens]                            446   e-125
gi|19923167 tubby isoform a [Homo sapiens]                            445   e-125
gi|157266334 tubby like protein 1 [Homo sapiens]                      355   7e-98
gi|238859545 tubby like protein 2 [Homo sapiens]                      274   2e-73
gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens]              74   4e-13
gi|157504499 ankyrin repeat domain 47 [Homo sapiens]                   35   0.21 
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa...    35   0.21 
gi|34452709 bromodomain containing 8 isoform 3 [Homo sapiens]          34   0.35 
gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens]          34   0.35 
gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens]          34   0.35 
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    33   0.46 
gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]            33   0.46 
gi|221136781 S1 RNA binding domain 1 [Homo sapiens]                    33   0.79 
gi|27886561 nuclear factor of activated T-cells, cytoplasmic, ca...    32   1.0  
gi|4505101 microtubule-associated protein 7 [Homo sapiens]             32   1.0  
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa...    32   1.3  
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa...    32   1.3  
gi|9966761 choroideremia isoform a [Homo sapiens]                      31   2.3  
gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens]           31   2.3  
gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]              31   3.0  
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa...    31   3.0  
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa...    31   3.0  
gi|55953102 tubby like protein 4 isoform 2 [Homo sapiens]              31   3.0  
gi|49170034 integrin, alpha 8 [Homo sapiens]                           31   3.0  
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    30   3.9  
gi|37595553 ring finger protein 111 [Homo sapiens]                     30   3.9  
gi|149773449 zinc finger protein 862 [Homo sapiens]                    30   3.9  
gi|53832014 choroideremia-like Rab escort protein 2 [Homo sapiens]     30   3.9  

>gi|238550202 tubby like protein 3 isoform 2 [Homo sapiens]
          Length = 501

 Score = 1019 bits (2634), Expect = 0.0
 Identities = 501/501 (100%), Positives = 501/501 (100%)

Query: 1   MEASRCRLSPSGDSVFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRA 60
           MEASRCRLSPSGDSVFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRA
Sbjct: 1   MEASRCRLSPSGDSVFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRA 60

Query: 61  KPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTAS 120
           KPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTAS
Sbjct: 61  KPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTAS 120

Query: 121 KPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTSGSATAAQPADN 180
           KPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTSGSATAAQPADN
Sbjct: 121 KPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTSGSATAAQPADN 180

Query: 181 LLGDIDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARK 240
           LLGDIDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARK
Sbjct: 181 LLGDIDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARK 240

Query: 241 RKKSKTANYLISIDPVDLSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHTR 300
           RKKSKTANYLISIDPVDLSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHTR
Sbjct: 241 RKKSKTANYLISIDPVDLSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHTR 300

Query: 301 QELAAISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQNNHDSLLSRWQNRTMENLVE 360
           QELAAISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQNNHDSLLSRWQNRTMENLVE
Sbjct: 301 QELAAISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQNNHDSLLSRWQNRTMENLVE 360

Query: 361 LHNKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNY 420
           LHNKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNY
Sbjct: 361 LHNKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNY 420

Query: 421 PLCAVQAFGIGLSSFDKCIQTLRMQELCELHRQHHSAASLVHRTVCQRWVGHPWRLLPQT 480
           PLCAVQAFGIGLSSFDKCIQTLRMQELCELHRQHHSAASLVHRTVCQRWVGHPWRLLPQT
Sbjct: 421 PLCAVQAFGIGLSSFDKCIQTLRMQELCELHRQHHSAASLVHRTVCQRWVGHPWRLLPQT 480

Query: 481 SLLWTDLSPPPVVPAPHQISM 501
           SLLWTDLSPPPVVPAPHQISM
Sbjct: 481 SLLWTDLSPPPVVPAPHQISM 501


>gi|21536436 tubby like protein 3 isoform 1 [Homo sapiens]
          Length = 442

 Score =  878 bits (2269), Expect = 0.0
 Identities = 436/436 (100%), Positives = 436/436 (100%)

Query: 1   MEASRCRLSPSGDSVFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRA 60
           MEASRCRLSPSGDSVFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRA
Sbjct: 1   MEASRCRLSPSGDSVFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRA 60

Query: 61  KPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTAS 120
           KPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTAS
Sbjct: 61  KPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTAS 120

Query: 121 KPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTSGSATAAQPADN 180
           KPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTSGSATAAQPADN
Sbjct: 121 KPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTSGSATAAQPADN 180

Query: 181 LLGDIDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARK 240
           LLGDIDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARK
Sbjct: 181 LLGDIDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARK 240

Query: 241 RKKSKTANYLISIDPVDLSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHTR 300
           RKKSKTANYLISIDPVDLSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHTR
Sbjct: 241 RKKSKTANYLISIDPVDLSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHTR 300

Query: 301 QELAAISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQNNHDSLLSRWQNRTMENLVE 360
           QELAAISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQNNHDSLLSRWQNRTMENLVE
Sbjct: 301 QELAAISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQNNHDSLLSRWQNRTMENLVE 360

Query: 361 LHNKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNY 420
           LHNKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNY
Sbjct: 361 LHNKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNY 420

Query: 421 PLCAVQAFGIGLSSFD 436
           PLCAVQAFGIGLSSFD
Sbjct: 421 PLCAVQAFGIGLSSFD 436


>gi|29826279 tubby isoform b [Homo sapiens]
          Length = 506

 Score =  446 bits (1148), Expect = e-125
 Identities = 245/491 (49%), Positives = 316/491 (64%), Gaps = 71/491 (14%)

Query: 14  SVFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRAKPRASDEQTPLVN 73
           SV  +E   +RQ KLD QR LLE++Q+KKR EP MVQ N + R R  + R S+EQ PLV 
Sbjct: 13  SVLDDEGRNLRQQKLDRQRALLEQKQKKKRQEPLMVQANADGRPRSRRARQSEEQAPLVE 72

Query: 74  CHTPHSNVILH------------------------------------------------- 84
            +   S    +                                                 
Sbjct: 73  SYLSSSGSTSYQVQEADSLASVQLGATRPTAPASAKRTKAAATAGGQGGAARKEKKGKHK 132

Query: 85  GIDGPAAVLKP-DEVHAPSVSSSVVEED-AENTVDTASKPG-------LQERLQKHDISE 135
           G  GPAA+ +   E   P    +V + D A++  +TA+  G       L+  +Q+  IS 
Sbjct: 133 GTSGPAALAEDKSEAQGPVQILTVGQSDHAQDAGETAAGGGERPSGQDLRATMQRKGISS 192

Query: 136 SVNFDE----ETDGISQSACLE---RPNSASSQNSTDTGTSGSATAA--QPADNLLGDID 186
           S++FDE    E +  S S+ L    RP+SA+S+ S     S  +  A  QP D    ++ 
Sbjct: 193 SMSFDEDEEDEEENSSSSSQLNSNTRPSSATSRKSVREAASAPSPTAPEQPVDV---EVQ 249

Query: 187 DLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARKRKKSKT 246
           DLE+F   PAPQG+T++CRI RDK+GMDRG++PTY+++L++E+ +K+FLLA RKRKKSKT
Sbjct: 250 DLEEFALRPAPQGITIKCRITRDKKGMDRGMYPTYFLHLDREDGKKVFLLAGRKRKKSKT 309

Query: 247 ANYLISIDPVDLSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHT-RQELAA 305
           +NYLIS+DP DLSR G+SY+GKLRSNLMGTKFTVYD G+ P K       + T RQELAA
Sbjct: 310 SNYLISVDPTDLSRGGDSYIGKLRSNLMGTKFTVYDNGVNPQKASSSTLESGTLRQELAA 369

Query: 306 ISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQNNHDSLLSRWQNRTMENLVELHNKA 365
           + YETNVLGFKGPRKMSVI+PGM + H+++  +P+N H++LL+RWQN+  E+++EL NK 
Sbjct: 370 VCYETNVLGFKGPRKMSVIVPGMNMVHERVSIRPRNEHETLLARWQNKNTESIIELQNKT 429

Query: 366 PVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNYPLCAV 425
           PVWN DTQSYVLNF GRVTQASVKNFQI+H NDPDYIVMQFGRVA+DVFT+DYNYPLCA+
Sbjct: 430 PVWNDDTQSYVLNFHGRVTQASVKNFQIIHGNDPDYIVMQFGRVAEDVFTMDYNYPLCAL 489

Query: 426 QAFGIGLSSFD 436
           QAF I LSSFD
Sbjct: 490 QAFAIALSSFD 500


>gi|19923167 tubby isoform a [Homo sapiens]
          Length = 561

 Score =  445 bits (1144), Expect = e-125
 Identities = 244/490 (49%), Positives = 315/490 (64%), Gaps = 71/490 (14%)

Query: 15  VFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRAKPRASDEQTPLVNC 74
           V  +E   +RQ KLD QR LLE++Q+KKR EP MVQ N + R R  + R S+EQ PLV  
Sbjct: 69  VLDDEGRNLRQQKLDRQRALLEQKQKKKRQEPLMVQANADGRPRSRRARQSEEQAPLVES 128

Query: 75  HTPHSNVILH-------------------------------------------------G 85
           +   S    +                                                 G
Sbjct: 129 YLSSSGSTSYQVQEADSLASVQLGATRPTAPASAKRTKAAATAGGQGGAARKEKKGKHKG 188

Query: 86  IDGPAAVLKP-DEVHAPSVSSSVVEED-AENTVDTASKPG-------LQERLQKHDISES 136
             GPAA+ +   E   P    +V + D A++  +TA+  G       L+  +Q+  IS S
Sbjct: 189 TSGPAALAEDKSEAQGPVQILTVGQSDHAQDAGETAAGGGERPSGQDLRATMQRKGISSS 248

Query: 137 VNFDE----ETDGISQSACLE---RPNSASSQNSTDTGTSGSATAA--QPADNLLGDIDD 187
           ++FDE    E +  S S+ L    RP+SA+S+ S     S  +  A  QP D    ++ D
Sbjct: 249 MSFDEDEEDEEENSSSSSQLNSNTRPSSATSRKSVREAASAPSPTAPEQPVDV---EVQD 305

Query: 188 LEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARKRKKSKTA 247
           LE+F   PAPQG+T++CRI RDK+GMDRG++PTY+++L++E+ +K+FLLA RKRKKSKT+
Sbjct: 306 LEEFALRPAPQGITIKCRITRDKKGMDRGMYPTYFLHLDREDGKKVFLLAGRKRKKSKTS 365

Query: 248 NYLISIDPVDLSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHT-RQELAAI 306
           NYLIS+DP DLSR G+SY+GKLRSNLMGTKFTVYD G+ P K       + T RQELAA+
Sbjct: 366 NYLISVDPTDLSRGGDSYIGKLRSNLMGTKFTVYDNGVNPQKASSSTLESGTLRQELAAV 425

Query: 307 SYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQNNHDSLLSRWQNRTMENLVELHNKAP 366
            YETNVLGFKGPRKMSVI+PGM + H+++  +P+N H++LL+RWQN+  E+++EL NK P
Sbjct: 426 CYETNVLGFKGPRKMSVIVPGMNMVHERVSIRPRNEHETLLARWQNKNTESIIELQNKTP 485

Query: 367 VWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNYPLCAVQ 426
           VWN DTQSYVLNF GRVTQASVKNFQI+H NDPDYIVMQFGRVA+DVFT+DYNYPLCA+Q
Sbjct: 486 VWNDDTQSYVLNFHGRVTQASVKNFQIIHGNDPDYIVMQFGRVAEDVFTMDYNYPLCALQ 545

Query: 427 AFGIGLSSFD 436
           AF I LSSFD
Sbjct: 546 AFAIALSSFD 555


>gi|157266334 tubby like protein 1 [Homo sapiens]
          Length = 542

 Score =  355 bits (910), Expect = 7e-98
 Identities = 170/278 (61%), Positives = 218/278 (78%), Gaps = 3/278 (1%)

Query: 159 SSQNSTDTGTSGSATAAQPADNLLGDIDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLF 218
           S+Q     G        + A +   ++D+  +FV  PAPQG TVRCR+ RDK+GMDRG++
Sbjct: 262 SNQKGKAKGKGKKKAKEERAPSPPVEVDEPREFVLRPAPQGRTVRCRLTRDKKGMDRGMY 321

Query: 219 PTYYMYLEKEENQKIFLLAARKRKKSKTANYLISIDPVDLSREGESYVGKLRSNLMGTKF 278
           P+Y+++L+ E+  K+FLLA RKRK+SKTANYLISIDP +LSR GE+++GKLRSNL+G +F
Sbjct: 322 PSYFLHLDTEK--KVFLLAGRKRKRSKTANYLISIDPTNLSRGGENFIGKLRSNLLGNRF 379

Query: 279 TVYDRGICPMKGRGLVGAAHTRQELAAISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQ 338
           TV+D G  P +G      A  RQELAA+ YETNVLGF+GPR+M+VIIPGM+  ++++P +
Sbjct: 380 TVFDNGQNPQRGYS-TNVASLRQELAAVIYETNVLGFRGPRRMTVIIPGMSAENERVPIR 438

Query: 339 PQNNHDSLLSRWQNRTMENLVELHNKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKND 398
           P+N  D LL RWQN+T+E+L+ELHNK PVWN D+ SY LNF+GRVTQASVKNFQIVH +D
Sbjct: 439 PRNASDGLLVRWQNKTLESLIELHNKPPVWNDDSGSYTLNFQGRVTQASVKNFQIVHADD 498

Query: 399 PDYIVMQFGRVADDVFTLDYNYPLCAVQAFGIGLSSFD 436
           PDYIV+QFGRVA+D FTLDY YPLCA+QAF I LSSFD
Sbjct: 499 PDYIVLQFGRVAEDAFTLDYRYPLCALQAFAIALSSFD 536


>gi|238859545 tubby like protein 2 [Homo sapiens]
          Length = 520

 Score =  274 bits (700), Expect = 2e-73
 Identities = 146/335 (43%), Positives = 205/335 (61%), Gaps = 9/335 (2%)

Query: 111 DAENTVDTASKPGLQ-----ERL--QKHDISESVNFDEETDGISQSACL--ERPNSASSQ 161
           DA  + +    PG+      E L  QK +  E      E+ G + SA    E   +   +
Sbjct: 186 DAHKSPNMGPNPGMDGDCVYENLAFQKEEDLEKKREASESTGTNSSAAHNEELSKALKGE 245

Query: 162 NSTDTGTSGSATAAQPADNLLGDIDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTY 221
             TD+       +        G  +D+E +V  PA  G  ++C + RDK G+D+GLFP Y
Sbjct: 246 GGTDSDHMRHEASLAIRSPCPGLEEDMEAYVLRPALPGTMMQCYLTRDKHGVDKGLFPLY 305

Query: 222 YMYLEKEENQKIFLLAARKRKKSKTANYLISIDPVDLSREGESYVGKLRSNLMGTKFTVY 281
           Y+YLE  ++ + FLLA RKR++SKT+NYLIS+DP  LSR+G+++VGK+RSN+  TKFT++
Sbjct: 306 YLYLETSDSLQRFLLAGRKRRRSKTSNYLISLDPTHLSRDGDNFVGKVRSNVFSTKFTIF 365

Query: 282 DRGICPMKGRGLVGAAHTRQELAAISYETNVLGFKGPRKMSVIIPGMTLNHKQIPYQPQN 341
           D G+ P +       A  RQEL A+ YE NVLG+ GPRKM+VI+PG    +++I  QP N
Sbjct: 366 DNGVNPDREHLTRNTARIRQELGAVCYEPNVLGYLGPRKMTVILPGTNSQNQRINVQPLN 425

Query: 342 NHDSLLSRWQNRTMENLVELHNKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDY 401
             +SLLSR+Q    + L+ LHNK P W+ +   Y LNF GRVT+ASVKNFQIV     ++
Sbjct: 426 EQESLLSRYQRGDKQGLLLLHNKTPSWDKENGVYTLNFHGRVTRASVKNFQIVDPKHQEH 485

Query: 402 IVMQFGRVADDVFTLDYNYPLCAVQAFGIGLSSFD 436
           +V+QFGRV  D FT+D+ +P   +QAF I LSSF+
Sbjct: 486 LVLQFGRVGPDTFTMDFCFPFSPLQAFSICLSSFN 520



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 21/41 (51%), Positives = 27/41 (65%)

Query: 15 VFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEA 55
          +   E+  MR  KL+ QR L EK+QR+KR E  MVQ NP+A
Sbjct: 12 ILGHELAAMRLQKLEQQRRLFEKKQRQKRQELLMVQANPDA 52


>gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens]
          Length = 1543

 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 37/72 (51%), Positives = 46/72 (63%), Gaps = 3/72 (4%)

Query: 363  NKAPVWNSDTQSYVLNFRGRVTQASVKNFQIVHKNDPDYIVMQFGRVADDVFTLDYNYPL 422
            NK P+WN  TQ Y L+F GRVTQ S KNFQI  +      VMQFGR+    + LD+ YP 
Sbjct: 1469 NKQPLWNEATQVYQLDFGGRVTQESAKNFQIELEGRQ---VMQFGRIDGSAYILDFQYPF 1525

Query: 423  CAVQAFGIGLSS 434
             AVQAF + L++
Sbjct: 1526 SAVQAFAVALAN 1537



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 13/63 (20%)

Query: 264 SYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHTRQELAAISYETNVLGFKGPRKMSV 323
           +Y+ ++ SN+ GTKF +           GL  AA     L A+ Y+T++L  + PR+M++
Sbjct: 594 NYLAQVTSNIWGTKFKIV----------GL--AAFLPTNLGAVIYKTSLLHLQ-PRQMTI 640

Query: 324 IIP 326
            +P
Sbjct: 641 YLP 643


>gi|157504499 ankyrin repeat domain 47 [Homo sapiens]
          Length = 821

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 52/208 (25%), Positives = 77/208 (37%), Gaps = 30/208 (14%)

Query: 18  EEMMKMRQAKLDYQRLLLEK-RQRKKRLEPFMVQPNPEARLRRAKPRASDEQTP------ 70
           E  +++ +A L++QR + E  R R + LE         A   RA+ R +  QTP      
Sbjct: 352 ERELELLRASLEHQRGVSELLRGRLRELEEAREAAEEAAAGARAQLREATTQTPWSCAEK 411

Query: 71  LVNCHTPHSNVILHGIDGPAAVLKPDEVHAPS--VSSSVVEEDAENTVDTASKP------ 122
                +P     L     P + +  D   AP+  + S + + D       +S P      
Sbjct: 412 AAQTESPAEAPSLTQESSPGS-MDGDRAVAPAGILKSIMKKRDGTPGAQPSSGPKSLQFV 470

Query: 123 ----GLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTSGSATAAQPA 178
               G  E     D S+S       DG S++   E P S+S       G S S T   P+
Sbjct: 471 GVLNGEYESSSSEDASDS-------DGDSENGGAEPPGSSSGSGDDSGGGSDSGTPGPPS 523

Query: 179 DNLLGDIDDLEDFVYSPAPQGVTVRCRI 206
               GDI D E    +   Q    RC +
Sbjct: 524 G---GDIRDPEPEAEAEPQQVAQGRCEL 548


>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
            sapiens]
          Length = 2881

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 26/112 (23%), Positives = 45/112 (40%), Gaps = 5/112 (4%)

Query: 86   IDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDG 145
            +D P A  +  +   P+   + V+E+ + +   + + GL+   QK  +++   FD E   
Sbjct: 2301 LDSPGAATEYSDPSVPTPPGAGVKEEHDQSTQMSKEGGLKLTFQKQGLAQKRPFDGEDGA 2360

Query: 146  ISQSACLERPNSASSQNSTD-----TGTSGSATAAQPADNLLGDIDDLEDFV 192
            + Q   L R     S + T           S T+ QP     G I D +  V
Sbjct: 2361 LGQQQYLTRLRELQSASETSLVNFPKSIPVSGTSIQPTLGANGVILDNQPIV 2412


>gi|34452709 bromodomain containing 8 isoform 3 [Homo sapiens]
          Length = 757

 Score = 33.9 bits (76), Expect = 0.35
 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 24/96 (25%)

Query: 67  EQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTASKPGLQE 126
           ++TPL N  T  S               P+ + +PS  S+ +E+  E   +T  K  + +
Sbjct: 461 DETPLTNVKTEAS---------------PESMLSPSHGSNPIEDPLE--AETQHKFEMSD 503

Query: 127 RLQKHD-------ISESVNFDEETDGISQSACLERP 155
            L++         I ++   DEE DG+S++A LE P
Sbjct: 504 SLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEP 539


>gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens]
          Length = 1235

 Score = 33.9 bits (76), Expect = 0.35
 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 24/96 (25%)

Query: 67  EQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTASKPGLQE 126
           ++TPL N  T  S               P+ + +PS  S+ +E+  E   +T  K  + +
Sbjct: 567 DETPLTNVKTEAS---------------PESMLSPSHGSNPIEDPLE--AETQHKFEMSD 609

Query: 127 RLQKHD-------ISESVNFDEETDGISQSACLERP 155
            L++         I ++   DEE DG+S++A LE P
Sbjct: 610 SLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEP 645


>gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens]
          Length = 951

 Score = 33.9 bits (76), Expect = 0.35
 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 24/96 (25%)

Query: 67  EQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTASKPGLQE 126
           ++TPL N  T  S               P+ + +PS  S+ +E+  E   +T  K  + +
Sbjct: 640 DETPLTNVKTEAS---------------PESMLSPSHGSNPIEDPLE--AETQHKFEMSD 682

Query: 127 RLQKHD-------ISESVNFDEETDGISQSACLERP 155
            L++         I ++   DEE DG+S++A LE P
Sbjct: 683 SLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEP 718


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 33.5 bits (75), Expect = 0.46
 Identities = 17/79 (21%), Positives = 38/79 (48%)

Query: 102 SVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQ 161
           S SS     D+ N+ D++      +  +  + S++ N  + ++    S   +  NS+ S 
Sbjct: 898 SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957

Query: 162 NSTDTGTSGSATAAQPADN 180
           NS+D+  S  ++ +  +D+
Sbjct: 958 NSSDSSNSSDSSDSNSSDS 976



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 17/77 (22%), Positives = 37/77 (48%)

Query: 104 SSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNS 163
           S S    D+ ++ D+++     +     D S+S N  +  D  + S   +  NS+ S NS
Sbjct: 747 SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNS 806

Query: 164 TDTGTSGSATAAQPADN 180
           +D+  S  ++ +  +++
Sbjct: 807 SDSSDSSDSSDSDSSNS 823



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 19/85 (22%), Positives = 39/85 (45%), Gaps = 4/85 (4%)

Query: 96  DEVHAPSVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERP 155
           D  ++   S S    ++ N+ D++      +     D S+S N  + +D  + S   E  
Sbjct: 872 DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDS----DSSDSSNSSDSSDSSNSSDSSESS 927

Query: 156 NSASSQNSTDTGTSGSATAAQPADN 180
           NS+ + NS+D+  S  ++ +  + N
Sbjct: 928 NSSDNSNSSDSSNSSDSSDSSDSSN 952



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 21/87 (24%), Positives = 41/87 (47%), Gaps = 5/87 (5%)

Query: 104 SSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNS 163
           S+S    D+ N+ D++      +     D S S +  + +D  + S   +  NS+ S NS
Sbjct: 909 SNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS---DSSNSSDSSNS 965

Query: 164 TDTGTSGSATAAQPADNLLGDIDDLED 190
           +D+  S S+ ++  +++   D  D  D
Sbjct: 966 SDSSDSNSSDSSDSSNS--SDSSDSSD 990



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 18/72 (25%), Positives = 33/72 (45%)

Query: 102  SVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQ 161
            S S+S    D+ N+ D++      +     D S S +  + +D    S   +  NS+ S 
Sbjct: 969  SDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSS 1028

Query: 162  NSTDTGTSGSAT 173
            NS+D+  S  ++
Sbjct: 1029 NSSDSSDSSDSS 1040



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 2/85 (2%)

Query: 104 SSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNS 163
           S S    D+ N+ D+       +     + S+S N  + +D  S S+  +  NS+ S NS
Sbjct: 771 SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDS-SDSSDSDSSNSSDSSNS 829

Query: 164 TDTG-TSGSATAAQPADNLLGDIDD 187
           +D+  +S S+ ++  +D+  G   D
Sbjct: 830 SDSSDSSNSSDSSDSSDSSDGSDSD 854



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 18/85 (21%), Positives = 41/85 (48%)

Query: 102 SVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQ 161
           S S+S    D  ++ D+++     +     D S+S +  + ++    S   +  NS+ S 
Sbjct: 643 SDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESS 702

Query: 162 NSTDTGTSGSATAAQPADNLLGDID 186
           +S+D+  S S+ ++  +++   D D
Sbjct: 703 DSSDSSDSDSSDSSDSSNSNSSDSD 727



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 17/85 (20%), Positives = 39/85 (45%)

Query: 96  DEVHAPSVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERP 155
           D   + + S S    D+ N+ D++      +     + S+S +    +D    S   +  
Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804

Query: 156 NSASSQNSTDTGTSGSATAAQPADN 180
           NS+ S +S+D+  S S+ ++  +++
Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNS 829



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 18/76 (23%), Positives = 34/76 (44%)

Query: 96   DEVHAPSVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERP 155
            D   +   S S    D+ ++ D++      +     D S+S + +E +D    S   +  
Sbjct: 1188 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSS 1247

Query: 156  NSASSQNSTDTGTSGS 171
            NS+ S +S+D+  S S
Sbjct: 1248 NSSDSSDSSDSSDSTS 1263



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 16/72 (22%), Positives = 34/72 (47%)

Query: 102  SVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQ 161
            S SS   + ++ ++ D+++     +     D S+S +    +D    S   +  NS+ S 
Sbjct: 963  SNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSS 1022

Query: 162  NSTDTGTSGSAT 173
            NS+D+  S  ++
Sbjct: 1023 NSSDSSNSSDSS 1034



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 20/87 (22%), Positives = 40/87 (45%), Gaps = 1/87 (1%)

Query: 102 SVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQ 161
           S SS        ++ D+++     +     D SES N  + ++    S   +  +S+ S 
Sbjct: 892 SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951

Query: 162 NSTD-TGTSGSATAAQPADNLLGDIDD 187
           NS+D + +S S+ ++  +D+   D  D
Sbjct: 952 NSSDSSNSSDSSNSSDSSDSNSSDSSD 978



 Score = 29.3 bits (64), Expect = 8.7
 Identities = 16/78 (20%), Positives = 35/78 (44%)

Query: 96   DEVHAPSVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERP 155
            D   +   S S    D+ ++ D+++     +     D S+S +  + +D    S   +  
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSS 1091

Query: 156  NSASSQNSTDTGTSGSAT 173
            NS+ S +S+D+  S  ++
Sbjct: 1092 NSSDSSDSSDSSDSSDSS 1109



 Score = 29.3 bits (64), Expect = 8.7
 Identities = 21/96 (21%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 96   DEVHAPSVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERP 155
            D  ++   S S    D+ ++ +++      E     D S+S +  + +D    S   +  
Sbjct: 1119 DSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1178

Query: 156  NSASSQNSTDTG-TSGSATAAQPADNLLGDIDDLED 190
            NS+ S +S+D+  +S S+ ++  +D+   D  D  D
Sbjct: 1179 NSSDSSDSSDSSDSSDSSDSSDSSDS--SDSSDSSD 1212


>gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
          Length = 906

 Score = 33.5 bits (75), Expect = 0.46
 Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 23/116 (19%)

Query: 185 IDDLEDFVYSPAPQGVTVRCRIIRDKRGMDRGLFPTYYMYLEKEENQKIFLLAARKRKKS 244
           ID  E+  ++P P       +IIR + G+  G   T +     ++  +      R  K S
Sbjct: 489 IDVNENPYFAPNP-------KIIRQEEGLHAGTMLTTFT---AQDPDRYMQQNIRYTKLS 538

Query: 245 KTANYLISIDPVD--------LSREGESYVGKLRSNLMGTKFTVYDRGICPMKGRG 292
             AN+L  IDPV+        L RE  +    +++N+    F   D GI PM G G
Sbjct: 539 DPANWL-KIDPVNGQITTIAVLDRESPN----VKNNIYNATFLASDNGIPPMSGTG 589


>gi|221136781 S1 RNA binding domain 1 [Homo sapiens]
          Length = 995

 Score = 32.7 bits (73), Expect = 0.79
 Identities = 34/158 (21%), Positives = 67/158 (42%), Gaps = 16/158 (10%)

Query: 53  PEARLRRAKPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDA 112
           P +R +     +  ++ P V  + P  +      DG   V+  +E+++    +    ED 
Sbjct: 48  PRSRKQPPPKESKPKRMPRVKKNAPQIS------DGSEVVVVKEELNSSVAIADTALEDR 101

Query: 113 ENTVDT-----ASKPGLQERLQKHDI--SESVNFDEETDGISQSACLERPNSASSQNSTD 165
           +N +DT      +K   +   Q H +  ++ +  +EET   S+++ LE  +++S   ST 
Sbjct: 102 KNKLDTVQTLKTAKTKQKCAAQPHTVRRTKKLKVEEET---SKASNLEGESNSSETPSTS 158

Query: 166 TGTSGSATAAQPADNLLGDIDDLEDFVYSPAPQGVTVR 203
           T   G+    +  D+       L+       PQG  V+
Sbjct: 159 TVWGGTCKKEENDDDFTFGQSALKKIKTETYPQGQPVK 196


>gi|27886561 nuclear factor of activated T-cells, cytoplasmic,
            calcineurin-dependent 3 isoform 1 [Homo sapiens]
          Length = 1075

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 33/119 (27%), Positives = 49/119 (41%), Gaps = 9/119 (7%)

Query: 51   PNPEARLRRAKPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEE 110
            P+P  R+   +     + T       P S++I H +  PA+   PD     +VS     E
Sbjct: 963  PSPATRMHSGQHSTQAQSTGQGGLSAP-SSLICHSLCDPAS-FPPD---GATVSIKPEPE 1017

Query: 111  DAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTS 169
            D E    T    GLQ+ +   D++E +  D     +SQ A + R     S  S D G S
Sbjct: 1018 DREPNFATI---GLQD-ITLDDVNEIIGRDMSQISVSQGAGVSRQAPLPSPESLDLGRS 1072


>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
          Length = 749

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 19/147 (12%)

Query: 2   EASRCRLSPSGDSVFHEEMMKMRQAK-LDYQRLLLEKRQRKKRLEPFMVQPNPEARLRRA 60
           EA R +     ++   EE  ++RQ +   +QR   E+ +RKKRLE  M       R RR 
Sbjct: 560 EAERAQRQKEEEARVREEAERVRQEREKHFQREEQERLERKKRLEEIM------KRTRRT 613

Query: 61  KPRASDEQTPLVNCHTPHSNVILHGIDGPAAV-LKPDEVHAPS----VSSSVVEEDAENT 115
           +  A+D++T        + ++    + G   V   P   +AP     V S  V    ++ 
Sbjct: 614 E--ATDKKT----SDQRNGDIAKGALTGGTEVSALPCTTNAPGNGKPVGSPHVVTSHQSK 667

Query: 116 VDTASKPGLQERLQKHDIS-ESVNFDE 141
           V   S P L+++  ++ +S ++ NF+E
Sbjct: 668 VTVESTPDLEKQPNENGVSVQNENFEE 694


>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
           sapiens]
          Length = 1297

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 44/210 (20%), Positives = 82/210 (39%), Gaps = 32/210 (15%)

Query: 15  VFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQ----------------PNPEARLR 58
           +  ++++  +   L+Y+R  LE++++ +RL+  + Q                P  +  L 
Sbjct: 460 ILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLY 519

Query: 59  RAKPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVH------------APSVSSS 106
             K   S  + P      PH  ++     GP A+     VH            A +V+S 
Sbjct: 520 HYKEGMSPSEKPAWAKEIPH--LVAVKSQGP-ALTASQSVHEQPTKGLSGFQEALNVTSH 576

Query: 107 VVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDT 166
            VE   +N+  T+  P L  R++K D S  +  +E+              + + +NS   
Sbjct: 577 RVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGN 636

Query: 167 GTS-GSATAAQPADNLLGDIDDLEDFVYSP 195
           G++ G    +QP      D+   E  + SP
Sbjct: 637 GSALGPRLGSQPIRASNPDLRRTEPILESP 666


>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
           sapiens]
          Length = 1305

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 44/210 (20%), Positives = 82/210 (39%), Gaps = 32/210 (15%)

Query: 15  VFHEEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQ----------------PNPEARLR 58
           +  ++++  +   L+Y+R  LE++++ +RL+  + Q                P  +  L 
Sbjct: 460 ILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLY 519

Query: 59  RAKPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVH------------APSVSSS 106
             K   S  + P      PH  ++     GP A+     VH            A +V+S 
Sbjct: 520 HYKEGMSPSEKPAWAKEIPH--LVAVKSQGP-ALTASQSVHEQPTKGLSGFQEALNVTSH 576

Query: 107 VVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDT 166
            VE   +N+  T+  P L  R++K D S  +  +E+              + + +NS   
Sbjct: 577 RVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGN 636

Query: 167 GTS-GSATAAQPADNLLGDIDDLEDFVYSP 195
           G++ G    +QP      D+   E  + SP
Sbjct: 637 GSALGPRLGSQPIRASNPDLRRTEPILESP 666


>gi|9966761 choroideremia isoform a [Homo sapiens]
          Length = 653

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 7/104 (6%)

Query: 98  VHAPSVSSSVVEEDAENTVDTASKPGLQ-----ERLQKHDISESVNFD-EETDGISQSAC 151
           VH    SS    ED E+ V     P  +     E+++K  I  ++ F+  ++  IS+S  
Sbjct: 506 VHLTCTSSKTAREDLESVVQKLFVPYTEMEIENEQVEKPRILWALYFNMRDSSDISRSCY 565

Query: 152 LERPNSASSQNSTDTGTSGSATAAQPADNLLGDIDDLEDFVYSP 195
            + P++    +  D G  G+  A + A+ L  +I   EDF   P
Sbjct: 566 NDLPSNVYVCSGPDCGL-GNDNAVKQAETLFQEICPNEDFCPPP 608


>gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens]
          Length = 640

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 45/193 (23%), Positives = 79/193 (40%), Gaps = 29/193 (15%)

Query: 19  EMMKMRQAKLDYQRLLLEKRQ---RKKRLEPFMVQP-NPEARLRRAKPRASDEQTPLVNC 74
           E +K+   K+D  R +   +Q   RKK L P  + P NP   +  +KP    E T  +N 
Sbjct: 401 EGLKILSGKIDQCRTIFLNKQPNPRKKLLVPCALDPPNPNCYVCASKP----EVTVRLNV 456

Query: 75  H-----TPHSNVILHGIDGPAAVLKPDEVHAPSVSSSVVEEDAENTVDTASKPGLQE--R 127
           H     T    ++       A  ++ ++     + SS   E   N     S+ G++   R
Sbjct: 457 HKVTVLTLQDKIVKEKFAMVAPDVQIEDGKGTILISSEEGETEANNHKKLSEFGIRNGSR 516

Query: 128 LQKHDI------------SESVNFDEETDGISQSACLERPNSASSQNSTDTGTSGSATAA 175
           LQ  D             SE +  D E + +  +   E+     ++++  + T+GS   A
Sbjct: 517 LQADDFLQDYTLLINILHSEDLGKDVEFEVVGDAP--EKVGPKQAEDAAKSITNGSDDGA 574

Query: 176 QPADNLLGDIDDL 188
           QP+ +   + DD+
Sbjct: 575 QPSTSTAQEQDDV 587


>gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]
          Length = 1272

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 36/146 (24%), Positives = 56/146 (38%), Gaps = 7/146 (4%)

Query: 49  VQPNPEARLRRAKPRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVH--APSVSSS 106
           V   PE  +R A+     +Q P+ N   P  + +    D P +   PD++   + SV + 
Sbjct: 847 VDNQPEELVRSAEDDEKPDQKPVTNECVPRISTVPTQPDNPFS--HPDKLKRMSKSVPAF 904

Query: 107 VVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDT 166
           + +E  +   DTAS+   Q    K   S   N    +   S S+      S  S  S D 
Sbjct: 905 LQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSV---SGSVMSVYSGDF 961

Query: 167 GTSGSATAAQPADNLLGDIDDLEDFV 192
           G        Q A   +  + +L  FV
Sbjct: 962 GNLEVKGNIQFAIEYVESLKELHVFV 987


>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
           sapiens]
          Length = 1268

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 45/207 (21%), Positives = 80/207 (38%), Gaps = 32/207 (15%)

Query: 18  EEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQ----------------PNPEARLRRAK 61
           EE  +  + + +Y+R  LE++++ +RL+  + Q                P  +  L   K
Sbjct: 434 EEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYK 493

Query: 62  PRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVH------------APSVSSSVVE 109
              S  + P      PH  ++     GP A+     VH            A +V+S  VE
Sbjct: 494 EGMSPSEKPAWAKEIPH--LVAVKSQGP-ALTASQSVHEQPTKGLSGFQEALNVTSHRVE 550

Query: 110 EDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTS 169
              +N+  T+  P L  R++K D S  +  +E+              + + +NS   G++
Sbjct: 551 MPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSA 610

Query: 170 -GSATAAQPADNLLGDIDDLEDFVYSP 195
            G    +QP      D+   E  + SP
Sbjct: 611 LGPRLGSQPIRASNPDLRRTEPILESP 637


>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
           sapiens]
          Length = 1276

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 45/207 (21%), Positives = 80/207 (38%), Gaps = 32/207 (15%)

Query: 18  EEMMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQ----------------PNPEARLRRAK 61
           EE  +  + + +Y+R  LE++++ +RL+  + Q                P  +  L   K
Sbjct: 434 EEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYK 493

Query: 62  PRASDEQTPLVNCHTPHSNVILHGIDGPAAVLKPDEVH------------APSVSSSVVE 109
              S  + P      PH  ++     GP A+     VH            A +V+S  VE
Sbjct: 494 EGMSPSEKPAWAKEIPH--LVAVKSQGP-ALTASQSVHEQPTKGLSGFQEALNVTSHRVE 550

Query: 110 EDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTS 169
              +N+  T+  P L  R++K D S  +  +E+              + + +NS   G++
Sbjct: 551 MPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSA 610

Query: 170 -GSATAAQPADNLLGDIDDLEDFVYSP 195
            G    +QP      D+   E  + SP
Sbjct: 611 LGPRLGSQPIRASNPDLRRTEPILESP 637


>gi|55953102 tubby like protein 4 isoform 2 [Homo sapiens]
          Length = 678

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 13/63 (20%)

Query: 264 SYVGKLRSNLMGTKFTVYDRGICPMKGRGLVGAAHTRQELAAISYETNVLGFKGPRKMSV 323
           +Y+ ++ SN+ GTKF +           GL  AA     L A+ Y+T++L  + PR+M++
Sbjct: 594 NYLAQVTSNIWGTKFKIV----------GL--AAFLPTNLGAVIYKTSLLHLQ-PRQMTI 640

Query: 324 IIP 326
            +P
Sbjct: 641 YLP 643


>gi|49170034 integrin, alpha 8 [Homo sapiens]
          Length = 1063

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 23/75 (30%), Positives = 30/75 (40%), Gaps = 11/75 (14%)

Query: 44  LEPFMVQPNPEARLRRAKPRASDEQTP-----LVNCHTPH------SNVILHGIDGPAAV 92
           L P   QPNP    +  KP AS E TP     L N   PH       +V+      PA +
Sbjct: 862 LGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSPAKI 921

Query: 93  LKPDEVHAPSVSSSV 107
           L    +    +S +V
Sbjct: 922 LNCTNIECLQISCAV 936


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 26/110 (23%), Positives = 44/110 (40%), Gaps = 12/110 (10%)

Query: 46  PFMVQPNPEARLRRAKPRASDEQTPLVNCHTPHSNVILHGID-------GPAAVLKPDEV 98
           P ++Q  P+       P+ +  QTP+V    PH+ ++L            P  V+KP  +
Sbjct: 740 PLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPLQPVPVVKPAVL 799

Query: 99  HAPSVSSSVVEEDAENTVDTASKPGLQERLQKHDISE-----SVNFDEET 143
                 S+V  + A    +   +PG        DI++      VN  EE+
Sbjct: 800 PGTKALSAVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASMAGVNLSEES 849


>gi|37595553 ring finger protein 111 [Homo sapiens]
          Length = 986

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 7/95 (7%)

Query: 90  AAVLKPDEVHAPSVSSSVVEEDAENTVDTASKPGLQERLQKHDISESVNFDEETDGISQS 149
           + V++P   +A  V    V+ED    V T S      R++    S S+N        S+ 
Sbjct: 369 STVIQPLRQNAAEVVDLTVDEDEPTVVPTTSA-----RMESQATSASIN--NSNPSTSEQ 421

Query: 150 ACLERPNSASSQNSTDTGTSGSATAAQPADNLLGD 184
           A        SSQ ST + TS + T+       +GD
Sbjct: 422 ASDTASAVTSSQPSTVSETSATLTSNSTTGTSIGD 456


>gi|149773449 zinc finger protein 862 [Homo sapiens]
          Length = 1169

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 43/163 (26%), Positives = 64/163 (39%), Gaps = 14/163 (8%)

Query: 20  MMKMRQAKLDYQRLLLEKRQRKKRLEPFMVQPNPEARL-RRAKPRASDEQTPLVNCHTPH 78
           M+  RQ +L Y+ ++    +    L P   +P+  ++L RRA P   D   P      P 
Sbjct: 349 MLDKRQKEL-YRDVMRMNYELLASLGPAAAKPDLISKLERRAAPWIKDPNGPKWGKGRPP 407

Query: 79  SN---VILHGIDGPAAVL-------KPDEVHAPSVSSSVVEE-DAENTVDTASKPGLQER 127
            N   V +   D  A+          P E  A   SSS+ EE D    +    +P   +R
Sbjct: 408 GNKKMVAVREADTQASAADSALLPGSPVEARASCCSSSICEEGDGPRRIKRTYRPRSIQR 467

Query: 128 LQKHDISESVNFDEETDGISQSACLERPNSASSQNSTDTGTSG 170
                    V   +ET  +  SAC+ERPN     +    G +G
Sbjct: 468 SWFGQFPWLVIDPKETK-LFCSACIERPNLHDKSSRLVRGYTG 509


>gi|53832014 choroideremia-like Rab escort protein 2 [Homo sapiens]
          Length = 656

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 7/104 (6%)

Query: 98  VHAPSVSSSVVEEDAENTVDTASKPGLQERLQKHDISE-----SVNFD-EETDGISQSAC 151
           VH    SS    ED E+ V     P  +  + + ++++     ++ F+  ++ GIS+S+ 
Sbjct: 508 VHLTCSSSKTAREDLESVVKKLFTPYTETEINEEELTKPRLLWALYFNMRDSSGISRSSY 567

Query: 152 LERPNSASSQNSTDTGTSGSATAAQPADNLLGDIDDLEDFVYSP 195
              P++    +  D G  G+  A + A+ L  +I   E+F   P
Sbjct: 568 NGLPSNVYVCSGPDCGL-GNEHAVKQAETLFQEIFPTEEFCPPP 610


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,245,669
Number of Sequences: 37866
Number of extensions: 930782
Number of successful extensions: 3110
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 3054
Number of HSP's gapped (non-prelim): 73
length of query: 501
length of database: 18,247,518
effective HSP length: 106
effective length of query: 395
effective length of database: 14,233,722
effective search space: 5622320190
effective search space used: 5622320190
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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