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Search of human proteins with 116063558
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116063558 tet oncogene family member 2 isoform b [Homo
sapiens]
(1165 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116063558 tet oncogene family member 2 isoform b [Homo sapiens] 2387 0.0
gi|187761317 tet oncogene family member 2 isoform a [Homo sapiens] 2325 0.0
gi|149944516 tet oncogene family member 3 [Homo sapiens] 68 6e-11
gi|221139761 zinc finger protein 853 [Homo sapiens] 55 3e-07
gi|33286444 mastermind-like 2 [Homo sapiens] 55 3e-07
gi|119372317 xin actin-binding repeat containing 2 isoform 1 [Ho... 55 5e-07
gi|93141033 PAX interacting protein 1 [Homo sapiens] 53 1e-06
gi|226246533 TOX high mobility group box family member 3 isoform... 51 7e-06
gi|226054295 TOX high mobility group box family member 3 isoform... 51 7e-06
gi|44890059 involucrin [Homo sapiens] 45 4e-04
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 44 7e-04
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 44 7e-04
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 44 7e-04
gi|114431248 hypothetical protein LOC205717 [Homo sapiens] 44 9e-04
gi|7657138 golgi integral membrane protein 4 [Homo sapiens] 42 0.003
gi|110347429 mediator complex subunit 12 [Homo sapiens] 41 0.006
gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens] 41 0.008
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens] 41 0.008
gi|120953251 neuron navigator 3 [Homo sapiens] 41 0.008
gi|49472835 bridging integrator 2 [Homo sapiens] 40 0.010
gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a... 40 0.013
gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b... 40 0.013
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 40 0.013
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 40 0.013
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 40 0.017
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 40 0.017
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 40 0.017
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 40 0.017
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 40 0.017
gi|148746195 trichohyalin [Homo sapiens] 39 0.022
>gi|116063558 tet oncogene family member 2 isoform b [Homo sapiens]
Length = 1165
Score = 2387 bits (6187), Expect = 0.0
Identities = 1165/1165 (100%), Positives = 1165/1165 (100%)
Query: 1 MEQDRTNHVEGNRLSPFLIPSPPICQTEPLATKLQNGSPLPERAHPEVNGDTKWHSFKSY 60
MEQDRTNHVEGNRLSPFLIPSPPICQTEPLATKLQNGSPLPERAHPEVNGDTKWHSFKSY
Sbjct: 1 MEQDRTNHVEGNRLSPFLIPSPPICQTEPLATKLQNGSPLPERAHPEVNGDTKWHSFKSY 60
Query: 61 YGIPCMKGSQNSRVSPDFTQESRGYSKCLQNGGIKRTVSEPSLSGLLQIKKLKQDQKANG 120
YGIPCMKGSQNSRVSPDFTQESRGYSKCLQNGGIKRTVSEPSLSGLLQIKKLKQDQKANG
Sbjct: 61 YGIPCMKGSQNSRVSPDFTQESRGYSKCLQNGGIKRTVSEPSLSGLLQIKKLKQDQKANG 120
Query: 121 ERRNFGVSQERNPGESSQPNVSDLSDKKESVSSVAQENAVKDFTSFSTHNCSGPENPELQ 180
ERRNFGVSQERNPGESSQPNVSDLSDKKESVSSVAQENAVKDFTSFSTHNCSGPENPELQ
Sbjct: 121 ERRNFGVSQERNPGESSQPNVSDLSDKKESVSSVAQENAVKDFTSFSTHNCSGPENPELQ 180
Query: 181 ILNEQEGKSANYHDKNIVLLKNKAVLMPNGATVSASSVEHTHGELLEKTLSQYYPDCVSI 240
ILNEQEGKSANYHDKNIVLLKNKAVLMPNGATVSASSVEHTHGELLEKTLSQYYPDCVSI
Sbjct: 181 ILNEQEGKSANYHDKNIVLLKNKAVLMPNGATVSASSVEHTHGELLEKTLSQYYPDCVSI 240
Query: 241 AVQKTTSHINAINSQATNELSCEITHPSHTSGQINSAQTSNSELPPKPAAVVSEACDADD 300
AVQKTTSHINAINSQATNELSCEITHPSHTSGQINSAQTSNSELPPKPAAVVSEACDADD
Sbjct: 241 AVQKTTSHINAINSQATNELSCEITHPSHTSGQINSAQTSNSELPPKPAAVVSEACDADD 300
Query: 301 ADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGEEFCSGSSSNL 360
ADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGEEFCSGSSSNL
Sbjct: 301 ADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGEEFCSGSSSNL 360
Query: 361 QAPGGSSERYLKQNEMNGAYFKQSSVFTKDSFSATTTPPPPSQLLLSPPPPLPQVPQLPS 420
QAPGGSSERYLKQNEMNGAYFKQSSVFTKDSFSATTTPPPPSQLLLSPPPPLPQVPQLPS
Sbjct: 361 QAPGGSSERYLKQNEMNGAYFKQSSVFTKDSFSATTTPPPPSQLLLSPPPPLPQVPQLPS 420
Query: 421 EGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERP 480
EGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERP
Sbjct: 421 EGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERP 480
Query: 481 QNNCVNRNDIQTAGTMTVPLCSEKTRPMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEI 540
QNNCVNRNDIQTAGTMTVPLCSEKTRPMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEI
Sbjct: 481 QNNCVNRNDIQTAGTMTVPLCSEKTRPMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEI 540
Query: 541 LKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAESHLKRNEASLPSILQYQPNLSNQM 600
LKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAESHLKRNEASLPSILQYQPNLSNQM
Sbjct: 541 LKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAESHLKRNEASLPSILQYQPNLSNQM 600
Query: 601 TSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQV 660
TSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQV
Sbjct: 601 TSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQV 660
Query: 661 HFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQ 720
HFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQ
Sbjct: 661 HFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQ 720
Query: 721 HKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTK 780
HKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTK
Sbjct: 721 HKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTK 780
Query: 781 VEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHL 840
VEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHL
Sbjct: 781 VEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHL 840
Query: 841 VSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYK 900
VSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYK
Sbjct: 841 VSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYK 900
Query: 901 NRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQ 960
NRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQ
Sbjct: 901 NRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQ 960
Query: 961 EQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWKKVTKQENPPASCDNVQ 1020
EQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWKKVTKQENPPASCDNVQ
Sbjct: 961 EQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWKKVTKQENPPASCDNVQ 1020
Query: 1021 QKSIIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVEMSGPVTVLTRQTTAAELDSHTPA 1080
QKSIIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVEMSGPVTVLTRQTTAAELDSHTPA
Sbjct: 1021 QKSIIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVEMSGPVTVLTRQTTAAELDSHTPA 1080
Query: 1081 LEQQTTSSEKTPTKRTAASVLNNFIESPSKLLDTPIKNLLDTPVKTQYDFPSCRCVGKCQ 1140
LEQQTTSSEKTPTKRTAASVLNNFIESPSKLLDTPIKNLLDTPVKTQYDFPSCRCVGKCQ
Sbjct: 1081 LEQQTTSSEKTPTKRTAASVLNNFIESPSKLLDTPIKNLLDTPVKTQYDFPSCRCVGKCQ 1140
Query: 1141 KCTETHGVYPELANLSSDMGFSFFF 1165
KCTETHGVYPELANLSSDMGFSFFF
Sbjct: 1141 KCTETHGVYPELANLSSDMGFSFFF 1165
>gi|187761317 tet oncogene family member 2 isoform a [Homo sapiens]
Length = 2002
Score = 2325 bits (6025), Expect = 0.0
Identities = 1136/1136 (100%), Positives = 1136/1136 (100%)
Query: 1 MEQDRTNHVEGNRLSPFLIPSPPICQTEPLATKLQNGSPLPERAHPEVNGDTKWHSFKSY 60
MEQDRTNHVEGNRLSPFLIPSPPICQTEPLATKLQNGSPLPERAHPEVNGDTKWHSFKSY
Sbjct: 1 MEQDRTNHVEGNRLSPFLIPSPPICQTEPLATKLQNGSPLPERAHPEVNGDTKWHSFKSY 60
Query: 61 YGIPCMKGSQNSRVSPDFTQESRGYSKCLQNGGIKRTVSEPSLSGLLQIKKLKQDQKANG 120
YGIPCMKGSQNSRVSPDFTQESRGYSKCLQNGGIKRTVSEPSLSGLLQIKKLKQDQKANG
Sbjct: 61 YGIPCMKGSQNSRVSPDFTQESRGYSKCLQNGGIKRTVSEPSLSGLLQIKKLKQDQKANG 120
Query: 121 ERRNFGVSQERNPGESSQPNVSDLSDKKESVSSVAQENAVKDFTSFSTHNCSGPENPELQ 180
ERRNFGVSQERNPGESSQPNVSDLSDKKESVSSVAQENAVKDFTSFSTHNCSGPENPELQ
Sbjct: 121 ERRNFGVSQERNPGESSQPNVSDLSDKKESVSSVAQENAVKDFTSFSTHNCSGPENPELQ 180
Query: 181 ILNEQEGKSANYHDKNIVLLKNKAVLMPNGATVSASSVEHTHGELLEKTLSQYYPDCVSI 240
ILNEQEGKSANYHDKNIVLLKNKAVLMPNGATVSASSVEHTHGELLEKTLSQYYPDCVSI
Sbjct: 181 ILNEQEGKSANYHDKNIVLLKNKAVLMPNGATVSASSVEHTHGELLEKTLSQYYPDCVSI 240
Query: 241 AVQKTTSHINAINSQATNELSCEITHPSHTSGQINSAQTSNSELPPKPAAVVSEACDADD 300
AVQKTTSHINAINSQATNELSCEITHPSHTSGQINSAQTSNSELPPKPAAVVSEACDADD
Sbjct: 241 AVQKTTSHINAINSQATNELSCEITHPSHTSGQINSAQTSNSELPPKPAAVVSEACDADD 300
Query: 301 ADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGEEFCSGSSSNL 360
ADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGEEFCSGSSSNL
Sbjct: 301 ADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGEEFCSGSSSNL 360
Query: 361 QAPGGSSERYLKQNEMNGAYFKQSSVFTKDSFSATTTPPPPSQLLLSPPPPLPQVPQLPS 420
QAPGGSSERYLKQNEMNGAYFKQSSVFTKDSFSATTTPPPPSQLLLSPPPPLPQVPQLPS
Sbjct: 361 QAPGGSSERYLKQNEMNGAYFKQSSVFTKDSFSATTTPPPPSQLLLSPPPPLPQVPQLPS 420
Query: 421 EGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERP 480
EGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERP
Sbjct: 421 EGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERP 480
Query: 481 QNNCVNRNDIQTAGTMTVPLCSEKTRPMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEI 540
QNNCVNRNDIQTAGTMTVPLCSEKTRPMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEI
Sbjct: 481 QNNCVNRNDIQTAGTMTVPLCSEKTRPMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEI 540
Query: 541 LKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAESHLKRNEASLPSILQYQPNLSNQM 600
LKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAESHLKRNEASLPSILQYQPNLSNQM
Sbjct: 541 LKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAESHLKRNEASLPSILQYQPNLSNQM 600
Query: 601 TSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQV 660
TSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQV
Sbjct: 601 TSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQV 660
Query: 661 HFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQ 720
HFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQ
Sbjct: 661 HFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQ 720
Query: 721 HKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTK 780
HKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTK
Sbjct: 721 HKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTK 780
Query: 781 VEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHL 840
VEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHL
Sbjct: 781 VEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHL 840
Query: 841 VSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYK 900
VSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYK
Sbjct: 841 VSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYK 900
Query: 901 NRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQ 960
NRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQ
Sbjct: 901 NRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQ 960
Query: 961 EQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWKKVTKQENPPASCDNVQ 1020
EQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWKKVTKQENPPASCDNVQ
Sbjct: 961 EQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWKKVTKQENPPASCDNVQ 1020
Query: 1021 QKSIIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVEMSGPVTVLTRQTTAAELDSHTPA 1080
QKSIIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVEMSGPVTVLTRQTTAAELDSHTPA
Sbjct: 1021 QKSIIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVEMSGPVTVLTRQTTAAELDSHTPA 1080
Query: 1081 LEQQTTSSEKTPTKRTAASVLNNFIESPSKLLDTPIKNLLDTPVKTQYDFPSCRCV 1136
LEQQTTSSEKTPTKRTAASVLNNFIESPSKLLDTPIKNLLDTPVKTQYDFPSCRCV
Sbjct: 1081 LEQQTTSSEKTPTKRTAASVLNNFIESPSKLLDTPIKNLLDTPVKTQYDFPSCRCV 1136
Score = 31.6 bits (70), Expect = 4.6
Identities = 31/129 (24%), Positives = 48/129 (37%), Gaps = 27/129 (20%)
Query: 874 PKQDLLHRCFQEQEQKSQQASVLQGYKNRNQDMSG--------QQAAQLAQQRYLIHNHA 925
P + R + ++ +++ S L+ N+N+ + A+Q Q L+
Sbjct: 1460 PVKTCRQRKLEAKKAAAEKLSSLENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSG 1519
Query: 926 NVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQEQQQTQQPQTESCHS---------Q 976
V Q + PPQ Q Q+ +QQQ PQTES +S
Sbjct: 1520 PVMQQSQQPQPLQKQPPQPQQQ----------QRPQQQQPHHPQTESVNSYSASGSTNPY 1569
Query: 977 MHRPIKVEP 985
M RP V P
Sbjct: 1570 MRRPNPVSP 1578
>gi|149944516 tet oncogene family member 3 [Homo sapiens]
Length = 1660
Score = 67.8 bits (164), Expect = 6e-11
Identities = 40/91 (43%), Positives = 50/91 (54%), Gaps = 14/91 (15%)
Query: 1049 KSQKQVKVEMSGPVTVLTRQTTAAELDSHTPALEQQTTSSEKTPTK--RTAASVLNNFIE 1106
+S KQ+K+E SG VTVL+ T + E TPTK L+ F+E
Sbjct: 617 RSPKQIKIESSGAVTVLS-----------TTCFHSEEGGQEATPTKAENPLTPTLSGFLE 665
Query: 1107 SPSKLLDTPIKNLLDTPVK-TQYDFPSCRCV 1136
SP K LDTP K+LLDTP K Q +FP+C CV
Sbjct: 666 SPLKYLDTPTKSLLDTPAKRAQAEFPTCDCV 696
Score = 32.3 bits (72), Expect = 2.7
Identities = 39/133 (29%), Positives = 54/133 (40%), Gaps = 26/133 (19%)
Query: 170 NCSGPENPELQILNEQEGKSANYHDKNIVLLKNK------AVLMPNGATVSASSVEHTHG 223
NC GPE P+ L EGK K++V+ + L P A + A S
Sbjct: 138 NCDGPECPDY--LEWLEGKI-----KSVVMEGGEERPRLPGPLPPGEAGLPAPSTR---- 186
Query: 224 ELLEKTLSQYYPD--------CVSIAVQKTTSHINAINSQATNELSCEITHPSHTSGQIN 275
LL + Q P +SIA +K S AI +A +LS + PSH++ Q
Sbjct: 187 PLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQA- 245
Query: 276 SAQTSNSELPPKP 288
S + PP P
Sbjct: 246 SCPLPEALSPPAP 258
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 55.5 bits (132), Expect = 3e-07
Identities = 90/407 (22%), Positives = 148/407 (36%), Gaps = 48/407 (11%)
Query: 689 SQTEKLMSPVLKQHLNQQASETEPFSNSHLLQH-KPHKQAAQTQPSQSSHLPQNQQQQQK 747
S++++ P + Q+ + + P S + + +P ++ Q Q Q P+ QQQ Q
Sbjct: 49 SESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQ--QLEQQPEPQQQPQH 106
Query: 748 LQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEECFHGENQYSKSSEFETHNVQMGLE 807
Q++ + L+ PQ + QQ S Q K + H E + Q+ +
Sbjct: 107 EQLQQPQPHLELQQQPQQDGQQQL--SQLQQEKHQSVHHQE--LKPELQLMHQQQQLQPQ 162
Query: 808 EVQNINRRNSPYSQTMKSSACKIQVSCSNNTHLVSENKEQTTHPELFAGNKTQNLHHMQY 867
+VQ R Q A + QV E +Q + + + L Q
Sbjct: 163 QVQEQQRLQQQQEQLQTQQAQEQQVLQQQ------EQLQQQVQEQQLLQQQQEQLQQQQL 216
Query: 868 FPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANV 927
+Q + QEQ Q+ QQ +LQ Q + QQ AQL QQ L+
Sbjct: 217 LQQQEQLQQQQFQQQ-QEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQ--LLEQQ--- 270
Query: 928 FPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQMHRPIKVEPGC 987
Q Q Q+ Q LQ+Q+QQQ Q Q E Q +P +EP
Sbjct: 271 -----QAQLQQQLLLQQQEQ---------LQQQQQQQLLQQQQEQLQQQQLQPPPLEPEE 316
Query: 988 KPHACMHTAPPENKTWKKVTKQENPPASCDNVQQKSIIETMEQHLKQFHAKSLFDHKALT 1047
+ + P + + +++ +Q + +Q+ + EQ Q +
Sbjct: 317 EEEVELELMPVDLGSEQELEQQRQ-----ELERQQELERQQEQRQLQLKLQEELQQLEQQ 371
Query: 1048 LKSQKQVKVEMSGPVTVLTRQTTAAELDSHTPALEQQTTSSEKTPTK 1094
L+ Q+Q L +Q EL +QQ E TP +
Sbjct: 372 LEQQQQ----------QLEQQEVQLELTPVELGAQQQEVQLELTPVQ 408
Score = 42.4 bits (98), Expect = 0.003
Identities = 73/343 (21%), Positives = 124/343 (36%), Gaps = 25/343 (7%)
Query: 615 LPRQAYTQKTTQLEHKSQMY-QVEMNQGQSQGTVDQHLQFQKPSHQV--HFSKTDHLPKA 671
L +Q Q+ Q E Q +E+ Q Q Q Q Q+ HQ H L
Sbjct: 94 LEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLM 153
Query: 672 HVQS-LCGTRFHFQQRADSQTEKLMSPVLKQH--LNQQASETEPFSNSHLLQHKPHKQAA 728
H Q L + QQR Q E+L + ++ L QQ + LLQ + +
Sbjct: 154 HQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQ 213
Query: 729 QTQPSQSSHLPQNQQQQQKLQIKNKEEIL----------QTFPHPQSNNDQQREGSFFGQ 778
Q Q L Q Q QQQ+ Q++ ++++L Q Q+ QQ Q
Sbjct: 214 QQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQ 273
Query: 779 TKVEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNT 838
+ + + Q + + + +Q E++Q + P + + ++++
Sbjct: 274 LQQQLLLQQQEQLQQQQQQQL--LQQQQEQLQQ-QQLQPPPLEPEEEEEVELELM---PV 327
Query: 839 HLVSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQG 898
L SE + + EL + Q L Q + Q+ L + Q+ EQ+ QQ +
Sbjct: 328 DLGSEQELEQQRQEL---ERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEV 384
Query: 899 YKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTP 941
G Q ++ + + + VP GG P
Sbjct: 385 QLELTPVELGAQQQEVQLELTPVQPELQLELVPAAGGGGAAVP 427
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 55.5 bits (132), Expect = 3e-07
Identities = 74/297 (24%), Positives = 109/297 (36%), Gaps = 37/297 (12%)
Query: 714 SNSHLLQHKPHKQAA-QTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQRE 772
S S + P QA QT S LP Q+ Q+K Q Q + Q +
Sbjct: 399 STSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQP 458
Query: 773 GSF-------------FGQTKVEECFHGENQYS-KSSEFETHNVQMGLEEVQ-NINRRNS 817
++ FGQ K+ G+ +S +SS G +V N +
Sbjct: 459 TNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAG 518
Query: 818 PYSQ------TMKSSACKIQVSCSNNTHLVSENKEQTTHPELFAGNKTQNLHHMQYFPNN 871
P +Q M+ + S NN H E ++ T P LF N Q M +
Sbjct: 519 PSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKP-LFHFNSDQANQQMP----S 573
Query: 872 VIPKQD---LLHRCFQEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVF 928
V+P Q+ LLH Q+Q+Q+ QQ Q + + Q QQ Q Q
Sbjct: 574 VLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQ---- 629
Query: 929 PVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQMHRPIKVEP 985
Q S Q+ Q+ + Q+Q+QQQ QQP ++ S +P+ P
Sbjct: 630 ---QQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSP 683
Score = 39.7 bits (91), Expect = 0.017
Identities = 37/146 (25%), Positives = 55/146 (37%), Gaps = 7/146 (4%)
Query: 608 NSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDH 667
N MP LP Q + + Q Q + Q Q Q Q Q Q+ Q S +
Sbjct: 568 NQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQ 627
Query: 668 LPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASE------TEPFSNSHL-LQ 720
+ S+ + QQ+ Q ++ +Q Q +S+ ++P S L LQ
Sbjct: 628 QQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQ 687
Query: 721 HKPHKQAAQTQPSQSSHLPQNQQQQQ 746
K Q Q QP +QQQ+Q
Sbjct: 688 QKLLLQQMQNQPIAGMGYQVSQQQRQ 713
Score = 38.5 bits (88), Expect = 0.038
Identities = 47/239 (19%), Positives = 87/239 (36%), Gaps = 11/239 (4%)
Query: 713 FSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQRE 772
F++ Q P +Q +PS + Q QQQQQ+ Q + +++ Q Q QQ++
Sbjct: 562 FNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 621
Query: 773 GSFFGQTKVEE--CFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKI 830
S Q + ++ + Q + + + Q ++ Q + +S +Q++ S
Sbjct: 622 SSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLR 681
Query: 831 QVSCSNNTHLVSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQE----- 885
L+ + + Q + ++ Q N P + C
Sbjct: 682 SPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPS-PNPCSNPNTGSG 740
Query: 886 --QEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPP 942
Q+S L G K Q +Q QL Q+ ++ + + P DQ H PP
Sbjct: 741 YMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAP-QDQINRHLSRPP 798
Score = 35.8 bits (81), Expect = 0.24
Identities = 53/237 (22%), Positives = 87/237 (36%), Gaps = 29/237 (12%)
Query: 562 PGWIELK-APRFHQAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGG---LPR 617
P W E+ A + Q ++ +++ Q+QP + + S G S P G +P
Sbjct: 425 PSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSS--AGPSPGPFGQEKIPS 482
Query: 618 QAYTQKTTQLEHKSQMYQVEMNQGQSQ---------------GTVDQHLQFQKPSHQVHF 662
++ Q+T + S M V GQS+ G +D +Q + F
Sbjct: 483 PSFGQQTFSPQ-SSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSF 541
Query: 663 SKTDHLPKAHVQSLCGTRFHFQQ-RADSQTEKLMSPVLKQHL------NQQASETEPFSN 715
H Q FHF +A+ Q ++ K L QQ + +
Sbjct: 542 INNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQ 601
Query: 716 SHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQRE 772
Q + +Q Q Q Q S + QQQQQ+ I +++ Q Q QQ++
Sbjct: 602 QQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQ 658
Score = 35.0 bits (79), Expect = 0.42
Identities = 27/118 (22%), Positives = 47/118 (39%)
Query: 653 FQKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEP 712
F S Q + LP + SL QQ+ Q ++ +Q QQ + +
Sbjct: 560 FHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 619
Query: 713 FSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQ 770
+S Q + +Q++ + Q Q QQQQQ+ Q + +++ Q P + Q
Sbjct: 620 QQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQ 677
>gi|119372317 xin actin-binding repeat containing 2 isoform 1 [Homo
sapiens]
Length = 3549
Score = 54.7 bits (130), Expect = 5e-07
Identities = 98/469 (20%), Positives = 164/469 (34%), Gaps = 77/469 (16%)
Query: 398 PPPPSQ------LLLSPPPPLPQVPQLPSEGKSTLNGGVLEEHHHYPNQSNTTLLREVKI 451
PPPPS L PPPPL P+ S + E +P + K
Sbjct: 2296 PPPPSNASSEIEFPLPPPPPLMMFPEKNGFLPSLSTEKIKAEFESFPGLPLPPPPVDEKS 2355
Query: 452 EGK-------PEAPPSQSPNPSTHVCSPSP---------MLSERPQNNCVN-RNDIQTAG 494
E + P PP+ S P+ + S +P S++ +N N + I T
Sbjct: 2356 ERESSSMFLPPPPPPTPSQKPAHLLSSSAPEKHSGDFMQQYSQKEASNSQNSQAKIITGK 2415
Query: 495 TMTVPLCSEKTRPMSEHLKHNPPIFGSSGELQDN-----CQQLMRNKEQEILKGRDKEQT 549
T +P + + +H+K N F EL + C+ +++++ E T
Sbjct: 2416 TGVLPPPTLPKPKLPKHIKDNKNDFSPKVELATSLSDMECKITTSKDQKKVMVMTSSEHT 2475
Query: 550 RDLVPPTQHYLKPGWIELKAPRFHQAE--SH------LKRNEASLPSILQYQ-PNLSNQM 600
Q+ + E K A SH R + P I + P S Q
Sbjct: 2476 E----TKQNVISKSLDERKQLSIDSANCLSHTVPGTSAPRKKQIAPLIKSHSFPESSGQQ 2531
Query: 601 TSKQYTGNSNMPGGLPRQAYTQKTTQLE---HKSQMYQVEMNQGQSQ--GTVDQHLQFQK 655
K Y P + + Y Q+ ++E +S Y + Q Q+Q V++ + QK
Sbjct: 2532 NPKPYMRKFKTPLMIAEEKYRQQKEEIEKQKQESSYYNIVKTQSQNQHITEVEKEMPLQK 2591
Query: 656 PSHQVHFSKTD-------------------------HLPKAHVQSLCGTRFHFQQRADSQ 690
+ +V S D L +++ R H A
Sbjct: 2592 TNEEVSLSGIDSECTVVQPSPGSQSNARILGVCSDNQLSTTSPETVAAKRLHHVLAASED 2651
Query: 691 TEKLMSPVLKQHLN-QQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQ 749
+K+ VL+ + Q+ SH Q +Q Q + + HLPQ++ +
Sbjct: 2652 KDKMKKEVLQSSRDIMQSKSACEIKQSH--QECSTQQTQQKKYLEQLHLPQSKPISPNFK 2709
Query: 750 IKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEECFHGENQYSKSSEFE 798
+K + L T H + D E S Q++++ + QY K+ + E
Sbjct: 2710 VKTIK--LPTLDHTLNETDHSYE-SHKQQSEIDVQTFTKKQYLKTKKTE 2755
Score = 34.3 bits (77), Expect = 0.71
Identities = 108/565 (19%), Positives = 193/565 (34%), Gaps = 79/565 (13%)
Query: 457 APPSQSPNPSTHVCSPSPMLSERPQNNCVNRNDIQTAGTMTVPLCSEKTRPMSEHLKHNP 516
+P SQS VCS + + + P+ R A + +K + E L+ +
Sbjct: 2611 SPGSQSNARILGVCSDNQLSTTSPETVAAKRLHHVLAAS------EDKDKMKKEVLQSSR 2664
Query: 517 PIFGSSGELQDNCQQLMRNKEQEILKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAE 576
I S C+ ++E + + K+ L P + P + ++K + +
Sbjct: 2665 DIMQSKSA----CEIKQSHQECSTQQTQQKKYLEQLHLPQSKPISPNF-KVKTIKLPTLD 2719
Query: 577 SHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQV 636
L + S S Q T KQY T+ +T+ HK
Sbjct: 2720 HTLNETDHSYESHKQQSEIDVQTFTKKQYLKTKK----------TEASTECSHK------ 2763
Query: 637 EMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHF---QQRADSQTEK 693
Q ++H Q K +V T LP +Q + +QR S +++
Sbjct: 2764 -------QSLAERHYQLPKKEKRV----TVQLPTESIQKNQEDKLKMVPRKQREFSGSDR 2812
Query: 694 LMSPVLKQHLNQQAS----ETEPFSNSHLLQHKPHKQAAQT--QPSQSSHLPQNQQQQQK 747
P ++ NQ S + E +H +K A + Q +HL Q Q+
Sbjct: 2813 GKLPGSEEK-NQGPSMIGRKEERLITERKHEHLKNKSAPKVVKQKVIDAHLDSQTQNFQQ 2871
Query: 748 LQIKNKEEILQTFPHPQSNNDQQ----------REGSFFGQTK--VEECFHGENQYSKSS 795
QI+ E + PQ N Q +E F TK +E ++ +S
Sbjct: 2872 TQIQTAESKAEHKKLPQPYNSLQEEKCLEVKGIQEKQVFSNTKDSKQEITQNKSFFSSVK 2931
Query: 796 EFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHLVSENKEQTTHPELFA 855
E + + + L V+ + +R Q + S + + + + + T L +
Sbjct: 2932 ESQRDDGKGALNIVEFLRKREE--LQQILSRVKQFEAEPNKSGLKTFQTLLNTIPGWLIS 2989
Query: 856 GNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYKNRNQD--MSGQQAAQ 913
+K + H+ N K+++ H K+Q +L Y+N Q MS +
Sbjct: 2990 EDKREYAVHIAMENNLEKVKEEITH-------IKTQAEDMLVSYENIIQTAMMSSKTGKP 3042
Query: 914 LAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQEQQQTQQPQTESC 973
+ L + V V +++ K ++ Q Q T
Sbjct: 3043 GNKPTSLDETSSKVSNVHVSNNKNSEQKENKIAKEKTV--------QHQVAAHHEATVRS 3094
Query: 974 HSQMHRPIKVEPGCKPHACMHTAPP 998
H + H+ IK++ P + T PP
Sbjct: 3095 HVKTHQEIKLDDSNIPPPSLKTRPP 3119
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 53.1 bits (126), Expect = 1e-06
Identities = 68/294 (23%), Positives = 105/294 (35%), Gaps = 63/294 (21%)
Query: 737 HLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEECFHGENQYSKSSE 796
++ N QQ + N ILQT P N +QQ S G T + + +
Sbjct: 340 NITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTP--- 396
Query: 797 FETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHLVSENK--EQTTHPELF 854
ETH +Q + Q ++ P ++Q +S+ +Q HP
Sbjct: 397 -ETHMLQQQQQAQQQ--QQQHPVLHLQPQQIMQLQ---QQQQQQISQQPYPQQPPHPFSQ 450
Query: 855 AGNKTQNLHHMQY------FPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYKNRNQ-DMS 907
+ Q H Q+ FP + LHR Q+ + QQ ++ Q + Q +
Sbjct: 451 QQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQ 510
Query: 908 GQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQEQQQTQQ 967
QQ AQL QQ LLQ+Q+QQQ QQ
Sbjct: 511 QQQLAQLQQQH------------------------------------SLLQQQQQQQIQQ 534
Query: 968 PQTESCHSQMHRPIKVEPGCKPH------ACMHTAPPENKTWKKVTKQENPPAS 1015
Q + H Q + +++ PH A H PP+ ++ +Q+ PP S
Sbjct: 535 QQLQRMHQQQQQQ-QMQSQTAPHLSQTSQALQHQVPPQQPPQQQ--QQQQPPPS 585
Score = 49.3 bits (116), Expect = 2e-05
Identities = 105/443 (23%), Positives = 152/443 (34%), Gaps = 72/443 (16%)
Query: 337 ENNIQGTTKLASGEEFCSGSSSNLQAPGGSSERYLKQNEMNGAYFKQSSVFTKDSFSATT 396
EN Q + S +E S +SS +P G + K N K +F S S+
Sbjct: 202 ENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKS---KGELMFDDSSDSS-- 256
Query: 397 TPPPPSQLLLSPPPPLPQVPQLPSEGKSTLNG---GVLEEHHHYPNQSNTTLLREVKIEG 453
P + L+ P +VPQL + + G G++ + P L EV+
Sbjct: 257 --PEKQERNLNWTPA--EVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPPEVRGNL 312
Query: 454 KPEAPPSQSPNPSTHVCSPSPMLSERPQNNCVNRNDIQTAGTMTVPLCSEKTRPMS-EHL 512
QS S + + SP + R N N DIQ + RP + H+
Sbjct: 313 MAAGQNLQSSERSEMIATWSPAV--RTLRNITNNADIQ-----------QMNRPSNVAHI 359
Query: 513 KHNPPIFGSSGELQDNCQQLMRNKEQEILKGRDKEQTRDLVPPTQHYLKPGWIELKAPRF 572
+ E Q N Q +L + K V P H L
Sbjct: 360 LQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVK------VTPETHML------------ 401
Query: 573 HQAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQ 632
Q + ++ + P +L QP Q+ +Q S P Y Q Q H
Sbjct: 402 -QQQQQAQQQQQQHP-VLHLQPQQIMQLQQQQQQQISQQP-------YPQ---QPPHPFS 449
Query: 633 MYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQRADSQTE 692
Q + Q Q LQF P Q+H + H P+ +Q FQQ+ Q +
Sbjct: 450 QQQQQQQQAHPHQFSQQQLQF--PQQQLHPPQQLHRPQQQLQP-------FQQQHALQQQ 500
Query: 693 KLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKN 752
L+QH QQ + H L + +Q Q Q Q H Q QQQ Q +
Sbjct: 501 ---FHQLQQHQLQQ-QQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPH 556
Query: 753 KEEILQTFPH---PQSNNDQQRE 772
+ Q H PQ QQ++
Sbjct: 557 LSQTSQALQHQVPPQQPPQQQQQ 579
Score = 44.3 bits (103), Expect = 7e-04
Identities = 55/257 (21%), Positives = 96/257 (37%), Gaps = 40/257 (15%)
Query: 647 VDQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVL----KQH 702
V+ Q ++ V FS+ P+ H+ QQ+ +Q ++ PVL +Q
Sbjct: 374 VNHSQQGHTNANAVLFSQVKVTPETHM---------LQQQQQAQQQQQQHPVLHLQPQQI 424
Query: 703 LNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPH 762
+ Q + + S Q PH + Q Q Q +H +Q QQ+LQ + Q P
Sbjct: 425 MQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAH--PHQFSQQQLQFPQQ----QLHPP 478
Query: 763 PQSNNDQQREGSFFGQTKVEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQT 822
Q + QQ+ F Q +++ FH + + H +Q Q + + +S
Sbjct: 479 QQLHRPQQQLQPFQQQHALQQQFH---------QLQQHQLQQ-----QQLAQLQQQHSLL 524
Query: 823 MKSSACKIQVSCSNNTHLVSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRC 882
+ +IQ H + ++ + +Q L H +P Q +
Sbjct: 525 QQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQ-------VPPQQPPQQQ 577
Query: 883 FQEQEQKSQQASVLQGY 899
Q+Q S Q L G+
Sbjct: 578 QQQQPPPSPQQHQLFGH 594
>gi|226246533 TOX high mobility group box family member 3 isoform 2
[Homo sapiens]
Length = 571
Score = 50.8 bits (120), Expect = 7e-06
Identities = 38/159 (23%), Positives = 62/159 (38%), Gaps = 19/159 (11%)
Query: 609 SNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHL 668
+ M G P TQ + ++ + Q++ Q Q Q + Q Q Q HQ+H +
Sbjct: 416 TTMVGSAPS---TQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQM 472
Query: 669 PKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAA 728
+ H Q H QQ Q + L + +Q L QQ + +QH+
Sbjct: 473 QQQHFQ------HHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPR 526
Query: 729 QTQPSQS----------SHLPQNQQQQQKLQIKNKEEIL 757
Q P S S P +QQ Q ++Q + + ++L
Sbjct: 527 QHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQVL 565
Score = 35.4 bits (80), Expect = 0.32
Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 699 LKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQ--SSHLPQN-QQQQQKLQIKNKEE 755
L+Q QQ + + L QH+ H+Q Q Q H+ Q+ QQQQQ LQ + ++
Sbjct: 440 LQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQ 499
Query: 756 ILQ 758
LQ
Sbjct: 500 QLQ 502
Score = 35.4 bits (80), Expect = 0.32
Identities = 33/129 (25%), Positives = 51/129 (39%), Gaps = 5/129 (3%)
Query: 884 QEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQ 943
Q+Q+Q+ QQ + Q QQ Q QQ++ H+ + Q Q Q
Sbjct: 441 QQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQ--HLQQQQQHLQQQINQ 498
Query: 944 KDTQKHAALRWHLLQKQEQQQTQQP---QTESCHSQMHRPIKVEPGCKPHACMHTAPPEN 1000
+ Q+ R L Q Q Q QP Q SQ+ PI +P + H + ++
Sbjct: 499 QQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQS 558
Query: 1001 KTWKKVTKQ 1009
+T +V Q
Sbjct: 559 QTQTQVLSQ 567
Score = 33.1 bits (74), Expect = 1.6
Identities = 32/148 (21%), Positives = 60/148 (40%), Gaps = 12/148 (8%)
Query: 938 TQTPPQKDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAP 997
TQ P TQ+H Q+Q+QQ Q Q + QMH+ I+ + + H H
Sbjct: 425 TQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQ-QQHFQHHMQQ 483
Query: 998 PENKTWKKVTKQENPPASCDNVQQKSIIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVE 1057
+ + + +Q N +QQ+ ++ + QH++ S H V +
Sbjct: 484 HLQQQQQHLQQQINQQQLQQQLQQRLQLQQL-QHMQHQSQPSPRQH--------SPVASQ 534
Query: 1058 MSGPVTVLTRQTTAAELDSHTPALEQQT 1085
++ P+ + A++ H ++ QT
Sbjct: 535 ITSPIPAIGSPQPASQ--QHQSQIQSQT 560
Score = 32.7 bits (73), Expect = 2.1
Identities = 21/94 (22%), Positives = 45/94 (47%), Gaps = 2/94 (2%)
Query: 727 AAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQRE--GSFFGQTKVEEC 784
+ QTQ Q Q QQQQQ++Q ++++ Q H Q Q++ Q ++
Sbjct: 430 SVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQ 489
Query: 785 FHGENQYSKSSEFETHNVQMGLEEVQNINRRNSP 818
H + Q ++ + ++ L+++Q++ ++ P
Sbjct: 490 QHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQP 523
Score = 32.3 bits (72), Expect = 2.7
Identities = 42/157 (26%), Positives = 55/157 (35%), Gaps = 12/157 (7%)
Query: 817 SPYSQTMKSSACKIQVSCSNNT--HLVSENKEQTTHPELFAGNKTQNL--HHMQYFPNNV 872
S TM SA QVS S T H + ++Q + + Q L H M
Sbjct: 412 SSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQ 471
Query: 873 IPKQDLLHRCFQEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPD 932
+ +Q H Q +Q+ Q + NQ QQ Q Q + L H P P
Sbjct: 472 MQQQHFQHHMQQHLQQQQQHLQ-----QQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPR 526
Query: 933 QG---GSHTQTPPQKDTQKHAALRWHLLQKQEQQQTQ 966
Q S +P A + H Q Q Q QTQ
Sbjct: 527 QHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQ 563
>gi|226054295 TOX high mobility group box family member 3 isoform 1
[Homo sapiens]
Length = 576
Score = 50.8 bits (120), Expect = 7e-06
Identities = 38/159 (23%), Positives = 62/159 (38%), Gaps = 19/159 (11%)
Query: 609 SNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHL 668
+ M G P TQ + ++ + Q++ Q Q Q + Q Q Q HQ+H +
Sbjct: 421 TTMVGSAPS---TQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQM 477
Query: 669 PKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAA 728
+ H Q H QQ Q + L + +Q L QQ + +QH+
Sbjct: 478 QQQHFQ------HHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPR 531
Query: 729 QTQPSQS----------SHLPQNQQQQQKLQIKNKEEIL 757
Q P S S P +QQ Q ++Q + + ++L
Sbjct: 532 QHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQVL 570
Score = 35.4 bits (80), Expect = 0.32
Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 699 LKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQ--SSHLPQN-QQQQQKLQIKNKEE 755
L+Q QQ + + L QH+ H+Q Q Q H+ Q+ QQQQQ LQ + ++
Sbjct: 445 LQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQ 504
Query: 756 ILQ 758
LQ
Sbjct: 505 QLQ 507
Score = 35.4 bits (80), Expect = 0.32
Identities = 33/129 (25%), Positives = 51/129 (39%), Gaps = 5/129 (3%)
Query: 884 QEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQ 943
Q+Q+Q+ QQ + Q QQ Q QQ++ H+ + Q Q Q
Sbjct: 446 QQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQ--HLQQQQQHLQQQINQ 503
Query: 944 KDTQKHAALRWHLLQKQEQQQTQQP---QTESCHSQMHRPIKVEPGCKPHACMHTAPPEN 1000
+ Q+ R L Q Q Q QP Q SQ+ PI +P + H + ++
Sbjct: 504 QQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQS 563
Query: 1001 KTWKKVTKQ 1009
+T +V Q
Sbjct: 564 QTQTQVLSQ 572
Score = 33.1 bits (74), Expect = 1.6
Identities = 32/148 (21%), Positives = 60/148 (40%), Gaps = 12/148 (8%)
Query: 938 TQTPPQKDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAP 997
TQ P TQ+H Q+Q+QQ Q Q + QMH+ I+ + + H H
Sbjct: 430 TQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQ-QQHFQHHMQQ 488
Query: 998 PENKTWKKVTKQENPPASCDNVQQKSIIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVE 1057
+ + + +Q N +QQ+ ++ + QH++ S H V +
Sbjct: 489 HLQQQQQHLQQQINQQQLQQQLQQRLQLQQL-QHMQHQSQPSPRQH--------SPVASQ 539
Query: 1058 MSGPVTVLTRQTTAAELDSHTPALEQQT 1085
++ P+ + A++ H ++ QT
Sbjct: 540 ITSPIPAIGSPQPASQ--QHQSQIQSQT 565
Score = 32.7 bits (73), Expect = 2.1
Identities = 21/94 (22%), Positives = 45/94 (47%), Gaps = 2/94 (2%)
Query: 727 AAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQRE--GSFFGQTKVEEC 784
+ QTQ Q Q QQQQQ++Q ++++ Q H Q Q++ Q ++
Sbjct: 435 SVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQ 494
Query: 785 FHGENQYSKSSEFETHNVQMGLEEVQNINRRNSP 818
H + Q ++ + ++ L+++Q++ ++ P
Sbjct: 495 QHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQP 528
Score = 32.3 bits (72), Expect = 2.7
Identities = 42/157 (26%), Positives = 55/157 (35%), Gaps = 12/157 (7%)
Query: 817 SPYSQTMKSSACKIQVSCSNNT--HLVSENKEQTTHPELFAGNKTQNL--HHMQYFPNNV 872
S TM SA QVS S T H + ++Q + + Q L H M
Sbjct: 417 SSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQ 476
Query: 873 IPKQDLLHRCFQEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPD 932
+ +Q H Q +Q+ Q + NQ QQ Q Q + L H P P
Sbjct: 477 MQQQHFQHHMQQHLQQQQQHLQ-----QQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPR 531
Query: 933 QG---GSHTQTPPQKDTQKHAALRWHLLQKQEQQQTQ 966
Q S +P A + H Q Q Q QTQ
Sbjct: 532 QHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQ 568
>gi|44890059 involucrin [Homo sapiens]
Length = 585
Score = 45.1 bits (105), Expect = 4e-04
Identities = 138/630 (21%), Positives = 218/630 (34%), Gaps = 151/630 (23%)
Query: 396 TTPPPPS---QLLLSP---PPPLPQVP-QLPSEGKSTLNGGVLEEHHHYPNQSNTTLLRE 448
T PPP + + + P PPP +VP +LP E S EE H
Sbjct: 22 TVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQ-----EEKHM------------ 64
Query: 449 VKIEGKPEAPPSQSPNPSTHVCSPSPMLSERPQNNCVNRNDIQTAGTMTVPLCSEKTRPM 508
++G PE Q P E Q + + Q A L EKT+
Sbjct: 65 TAVKGLPEQECEQQQK--------EPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRD 116
Query: 509 SEHLKHNPPIFGSSGELQDNCQQLMRNKEQEILK-----GRDKEQTRDLVPPTQHYLKPG 563
+ K +L++ + L + +QE++K G KEQ +L + +LK
Sbjct: 117 QQLNK----------QLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLK-- 164
Query: 564 WIELKAPRFHQAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYTQK 623
HL++ E L Q + L LP Q Q
Sbjct: 165 --------------HLEQQEGQLKHPEQQEGQLE-----------------LPEQQEGQL 193
Query: 624 TTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHF 683
+ + Q+ E +GQ + Q Q + P Q LP+ L
Sbjct: 194 ELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQ---EGQLELPQQQEGQL---ELSE 247
Query: 684 QQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQT-----QPSQSSHL 738
QQ + + LK HL Q + E P +Q Q Q Q HL
Sbjct: 248 QQEGQLELSEQQEGQLK-HLEHQEGQLEV----------PEEQMGQLKYLEQQEGQLKHL 296
Query: 739 PQNQQQ-----QQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVE-ECFHGENQYS 792
Q ++Q QQ Q+K+ E+ Q + +Q+EG + E + H E Q
Sbjct: 297 DQQEKQPELPEQQMGQLKHLEQ-----QEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEG 351
Query: 793 KSSEFETHNVQMGLEEVQNIN------RRNSPYSQTMKSSACKIQVSCSNNT-HLVSEN- 844
+ E Q+GL E Q + ++ P + K V HLV +
Sbjct: 352 QLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEG 411
Query: 845 -----KEQTTHPELFAGN------KTQNLHHMQYFPNNV-IPKQDLLHRCFQEQEQKSQQ 892
+ Q H E G + L H++ + +P+Q + EQE+K Q
Sbjct: 412 QLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEK--Q 469
Query: 893 ASVLQGYKNRNQDMSGQQAA-QLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAA 951
+ + + + + + Q+A +L +Q+ H +Q H + P Q+D Q
Sbjct: 470 LELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHL------EQQEKHLEHPEQQDGQ---- 519
Query: 952 LRWHLLQKQEQQQTQQPQTESCHSQMHRPI 981
L+ EQQ+ Q E Q+ +P+
Sbjct: 520 -----LKHLEQQEGQLKDLEQQKGQLEQPV 544
Score = 41.2 bits (95), Expect = 0.006
Identities = 91/455 (20%), Positives = 160/455 (35%), Gaps = 42/455 (9%)
Query: 570 PRFHQAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQA--YTQKTTQL 627
P + + +K+ P + L ++ SKQ + GLP Q QK Q
Sbjct: 25 PPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQE 84
Query: 628 EHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKT-DHLPKAHVQSLCGTRFHFQQR 686
+ Q + + + Q +Q L+ +K +K + K Q L ++
Sbjct: 85 QELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQ 144
Query: 687 ADSQTEKLMSPVLKQ-----HLNQQASETEPFSNSHLLQHKPHKQAAQTQ--PSQSSHLP 739
+ E+L+ +Q HL QQ + + P +Q Q + Q L
Sbjct: 145 LGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLE 204
Query: 740 QNQQQQQKLQIKNKEEILQTFPHPQSNN---DQQREGSFF------GQTKVEECFHGENQ 790
+QQ+ +L++ ++E P Q QQ+EG GQ ++ E G+ +
Sbjct: 205 LPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLK 264
Query: 791 YSKSSE--FETHNVQMG-LEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHLVSENKEQ 847
+ + E E QMG L+ ++ + Q K Q HL + + Q
Sbjct: 265 HLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQ-QMGQLKHL-EQQEGQ 322
Query: 848 TTHPELFAGNKTQ----------------NLHHMQYFPNNV-IPKQDLLH-RCFQEQEQK 889
H E G Q L H+++ + +P+Q +L + ++Q+ +
Sbjct: 323 PKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQ 382
Query: 890 SQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKH 949
+ +G GQ + Q+ L V + Q G Q+ KH
Sbjct: 383 PKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKH 442
Query: 950 AALRWHLLQKQEQQQTQQPQTESCHSQMHRPIKVE 984
+ L+ EQQ Q E Q+ P + E
Sbjct: 443 LEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQE 477
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 44.3 bits (103), Expect = 7e-04
Identities = 36/130 (27%), Positives = 58/130 (44%), Gaps = 12/130 (9%)
Query: 884 QEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQ 943
Q+Q+ ++QQ+++ Q ++ Q Q Q QQ + +H N + Q Q
Sbjct: 185 QQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQ---------Q 235
Query: 944 KDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTW 1003
+ Q+ A L+ LQ+Q+QQQ QQ Q + Q PI+ P +P A P+
Sbjct: 236 QQLQRIAQLQ---LQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQ 292
Query: 1004 KKVTKQENPP 1013
T+ PP
Sbjct: 293 MHHTQHHQPP 302
Score = 38.1 bits (87), Expect = 0.049
Identities = 43/161 (26%), Positives = 64/161 (39%), Gaps = 20/161 (12%)
Query: 617 RQAYTQKTTQLEHKSQMYQVEMN--QGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHVQ 674
+QA Q+ Q + + Q +Q + + Q Q Q V Q Q Q+ Q HL K H Q
Sbjct: 173 QQAALQQQQQ-QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQ-----QQHLIKLHHQ 226
Query: 675 SLCGTRFHFQQRADSQTEKLMSPV-LKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPS 733
+ QQ+ Q ++L L+ QQ + + LQ +P Q P
Sbjct: 227 N--------QQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQP---PIQQPPM 275
Query: 734 QSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGS 774
Q P +Q Q+LQ + + Q P PQ Q + S
Sbjct: 276 QQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPS 316
Score = 32.0 bits (71), Expect = 3.5
Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 11/111 (9%)
Query: 684 QQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQH----KPHKQAAQTQPSQSSHL- 738
QQ+ Q ++ L+Q QQ + S + Q +Q Q Q Q HL
Sbjct: 162 QQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLI 221
Query: 739 ---PQNQQQ--QQKLQIKNKEEI-LQTFPHPQSNNDQQREGSFFGQTKVEE 783
QNQQQ QQ+ Q++ ++ LQ Q QQ++ + Q +++
Sbjct: 222 KLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQ 272
Score = 32.0 bits (71), Expect = 3.5
Identities = 38/186 (20%), Positives = 69/186 (37%), Gaps = 13/186 (6%)
Query: 725 KQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEEC 784
+Q Q Q Q + L Q QQQQQ+ Q + ++ +Q QQ + Q + +
Sbjct: 164 QQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKL 223
Query: 785 FHGENQYSKSSEFETHNV-QMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHLVSE 843
H Q + + + + Q+ L++ Q ++ Q + IQ
Sbjct: 224 HHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQ---------QPP 274
Query: 844 NKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYKNRN 903
++ P + Q +HH Q+ P+Q + Q Q + S Q ++
Sbjct: 275 MQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPV---AQNQPSQLPPQSQTQPLVSQA 331
Query: 904 QDMSGQ 909
Q + GQ
Sbjct: 332 QALPGQ 337
Score = 31.2 bits (69), Expect = 6.0
Identities = 35/139 (25%), Positives = 51/139 (36%), Gaps = 18/139 (12%)
Query: 626 QLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQ 685
Q+ + Q Q + Q Q Q Q Q+ Q S +A VQ QQ
Sbjct: 157 QVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQ--------QQ 208
Query: 686 RADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQ 745
+ Q ++ + H NQQ + Q + ++ AQ Q Q Q QQQQ
Sbjct: 209 QLQQQQQQQQHLIKLHHQNQQQIQQ---------QQQQLQRIAQLQLQQQQQ-QQQQQQQ 258
Query: 746 QKLQIKNKEEILQTFPHPQ 764
Q+ Q + +Q P Q
Sbjct: 259 QQQQALQAQPPIQQPPMQQ 277
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 44.3 bits (103), Expect = 7e-04
Identities = 36/130 (27%), Positives = 58/130 (44%), Gaps = 12/130 (9%)
Query: 884 QEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQ 943
Q+Q+ ++QQ+++ Q ++ Q Q Q QQ + +H N + Q Q
Sbjct: 185 QQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQ---------Q 235
Query: 944 KDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTW 1003
+ Q+ A L+ LQ+Q+QQQ QQ Q + Q PI+ P +P A P+
Sbjct: 236 QQLQRIAQLQ---LQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQ 292
Query: 1004 KKVTKQENPP 1013
T+ PP
Sbjct: 293 MHHTQHHQPP 302
Score = 38.1 bits (87), Expect = 0.049
Identities = 43/161 (26%), Positives = 64/161 (39%), Gaps = 20/161 (12%)
Query: 617 RQAYTQKTTQLEHKSQMYQVEMN--QGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHVQ 674
+QA Q+ Q + + Q +Q + + Q Q Q V Q Q Q+ Q HL K H Q
Sbjct: 173 QQAALQQQQQ-QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQ-----QQHLIKLHHQ 226
Query: 675 SLCGTRFHFQQRADSQTEKLMSPV-LKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPS 733
+ QQ+ Q ++L L+ QQ + + LQ +P Q P
Sbjct: 227 N--------QQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQP---PIQQPPM 275
Query: 734 QSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGS 774
Q P +Q Q+LQ + + Q P PQ Q + S
Sbjct: 276 QQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPS 316
Score = 35.4 bits (80), Expect = 0.32
Identities = 86/431 (19%), Positives = 146/431 (33%), Gaps = 59/431 (13%)
Query: 725 KQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEEC 784
+Q Q Q Q + L Q QQQQQ+ Q + ++ +Q QQ + Q + +
Sbjct: 164 QQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKL 223
Query: 785 FHGENQYSKSSEFETHNV-QMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHLVSE 843
H Q + + + + Q+ L++ Q ++ Q + IQ
Sbjct: 224 HHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQ---------QPP 274
Query: 844 NKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYKNRN 903
++ P + Q +HH Q+ P+Q + Q Q SQ +++
Sbjct: 275 MQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPV-----AQNQPSQLPP-----QSQT 324
Query: 904 QDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQEQQ 963
Q + Q A Q Y TQ PP K + ++ +Q Q QQ
Sbjct: 325 QPLVSQAQALPGQMLY------------------TQ-PPLKFVRAPMVVQQPPVQPQVQQ 365
Query: 964 QTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWKKVTKQENPPASCDNVQQKS 1023
Q QT + ++V P M ++P + + PP Q S
Sbjct: 366 QQTAVQTAQAAQMVAPGVQVSQSSLP---MLSSPSPGQQVQTPQSMPPPPQPSPQPGQPS 422
Query: 1024 IIETMEQHLKQFHAKSLF--------DHKALTLKSQKQVKVEMSGPVTVLTRQTTAAELD 1075
+ S F +T ++ + V GP+ ++
Sbjct: 423 SQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPA 482
Query: 1076 SHTPALEQQTTSSEKTPTK--RTAASVLNNFIESPSKLLD-TPIKNLLDTPVKTQYDFPS 1132
+ A EQQ K +K ++N ++ + D + +K+LLD PS
Sbjct: 483 GSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTD-----PS 537
Query: 1133 CRCVGK-CQKC 1142
RC K QKC
Sbjct: 538 KRCPLKTLQKC 548
Score = 32.0 bits (71), Expect = 3.5
Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 11/111 (9%)
Query: 684 QQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQH----KPHKQAAQTQPSQSSHL- 738
QQ+ Q ++ L+Q QQ + S + Q +Q Q Q Q HL
Sbjct: 162 QQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLI 221
Query: 739 ---PQNQQQ--QQKLQIKNKEEI-LQTFPHPQSNNDQQREGSFFGQTKVEE 783
QNQQQ QQ+ Q++ ++ LQ Q QQ++ + Q +++
Sbjct: 222 KLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQ 272
Score = 31.2 bits (69), Expect = 6.0
Identities = 35/139 (25%), Positives = 51/139 (36%), Gaps = 18/139 (12%)
Query: 626 QLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQ 685
Q+ + Q Q + Q Q Q Q Q+ Q S +A VQ QQ
Sbjct: 157 QVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQ--------QQ 208
Query: 686 RADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQ 745
+ Q ++ + H NQQ + Q + ++ AQ Q Q Q QQQQ
Sbjct: 209 QLQQQQQQQQHLIKLHHQNQQQIQQ---------QQQQLQRIAQLQLQQQQQ-QQQQQQQ 258
Query: 746 QKLQIKNKEEILQTFPHPQ 764
Q+ Q + +Q P Q
Sbjct: 259 QQQQALQAQPPIQQPPMQQ 277
>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
Length = 1498
Score = 44.3 bits (103), Expect = 7e-04
Identities = 106/576 (18%), Positives = 212/576 (36%), Gaps = 67/576 (11%)
Query: 566 ELKAPRFH----QAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYT 621
E + R H Q H+ E L S + + + + S Q+ + +A
Sbjct: 898 EAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALK 957
Query: 622 QKTTQLEHKSQMYQVEMNQGQSQ--GTVDQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGT 679
++ +L+ +++ E Q + + + K H+ + + L + ++L
Sbjct: 958 KQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAA- 1016
Query: 680 RFHFQQRADSQTEKLMSP------VLKQHLNQQASETEPFSNSH---LLQHKPHKQAAQT 730
++ AD++ +L + L H QA E E + SH LL+ + + A T
Sbjct: 1017 ----KEAADAELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKELQEVIALT 1072
Query: 731 ----QPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEECFH 786
+ S+ L + Q+ + K + L+ + + +G G +
Sbjct: 1073 SQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALR 1132
Query: 787 GENQYSKSS--EFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHLVSEN 844
N +++ + E VQ+ L+ VQ + +R + MK +Q S V+
Sbjct: 1133 EHNSILETALAKREADLVQLNLQ-VQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSL 1191
Query: 845 KEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYKNRNQ 904
KEQ ++ AG H+ ++F + L +E + K LQ + Q
Sbjct: 1192 KEQVAAAKVEAG------HNRRHFKAASLE----LSEVKKELQAKEHLVQKLQAEADDLQ 1241
Query: 905 DMSGQQAAQLAQ-QRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQEQQ 963
G+ + ++AQ Q L A + + Q P Q+ L+W + QK+ +
Sbjct: 1242 IREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQP-VGNQEMENLKWEVDQKEREI 1300
Query: 964 QTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWKKVTKQENPPASCDNVQQKS 1023
Q+ + Q + Q + ++ G + +N + + Q+
Sbjct: 1301 QSLKQQLDLTEQQGRKELE---GLQ------------------QLLQNVKSELEMAQEDL 1339
Query: 1024 IIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVEMSGPVTVLTRQTTAAELDSHTPALEQ 1083
+ ++ + Q L ++ L+ +Q+K+++ TR+ E S PA
Sbjct: 1340 SMTQKDKFMLQAKVSELKNNMKTLLQQNQQLKLDLRRG-AAKTRKEPKGEASSSNPA--- 1395
Query: 1084 QTTSSEKTPTKRTAASVLNNFIESPSKLLDTPIKNL 1119
+ K P AS+L + P + P+KNL
Sbjct: 1396 ---TPIKIPDCPVPASLLEELLRPPPAVSKEPLKNL 1428
>gi|114431248 hypothetical protein LOC205717 [Homo sapiens]
Length = 2245
Score = 43.9 bits (102), Expect = 9e-04
Identities = 124/546 (22%), Positives = 192/546 (35%), Gaps = 92/546 (16%)
Query: 399 PPPSQLLLSPPPPLPQVPQLPSEGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAP 458
P + LL PP Q+P+ G++ PN+ N+ E +E +P
Sbjct: 1164 PSEASLLEGDPPFKSQIPKESGTGQAEAT----------PNEFNSQGSIEATME-RPLEK 1212
Query: 459 PSQSPNPSTHVCSPSPMLSERPQNNCVNRNDIQTAGTMTVPLCS---------EKTRPMS 509
PS S T S S+ P ++ N++ +++ PL S + T P +
Sbjct: 1213 PSCSLGIKTSNASLQDSTSQPPSITSLSVNNLIHQSSISHPLASCAGLSPTSEQTTVPAT 1272
Query: 510 EHLKHNPPIFGSSGELQDNCQQLMRNKEQEILKGRDKEQTRDLVPPTQHYLKPGWIELKA 569
+L + +GS Q LM QE L + + LKP K
Sbjct: 1273 VNLTVSSSSYGS----QPPGPSLMTEYSQEQLNTMTSTIPNSQIQ--EPLLKPSHESRKD 1326
Query: 570 PRFHQAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYTQKTTQLEH 629
+ L + A Q P M+ T P + Q + +
Sbjct: 1327 SAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRT-----PDTISDQTQMMVSQIPPN 1381
Query: 630 KSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQRADS 689
S N G + PS+ T L + VQ CG++ ++ +
Sbjct: 1382 SSNSVVPVSNPAHGDGLT----RLFPPSNNF---VTPALRQTEVQ--CGSQPSVAEQQQT 1432
Query: 690 QTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQ 749
Q + + L+QH+ Q SHL H H Q Q Q Q QQQQQ Q
Sbjct: 1433 QASQHLQ-ALQQHVPAQGV-------SHL--HSNHLYIKQQQQQQQQQ-QQQQQQQQAGQ 1481
Query: 750 IKNKEEILQT---FPHPQS-------NNDQQR---------------EGSFFGQTKVEEC 784
++ + + Q PH +S N QQR +G+ Q ++
Sbjct: 1482 LRERHHLYQMQHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQTSQLSLQPK 1541
Query: 785 FHGENQ-YSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHLVSE 843
HG +Q SK+ + H+ QM + Q+ SQT KS C+ S S N H +
Sbjct: 1542 HHGTDQSRSKTGQPHPHHQQMQQQMQQHFGS-----SQTEKS--CE-NPSTSRNHHNHPQ 1593
Query: 844 N--KEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYKN 901
N + H + G++ Q + P Q LL EQ+ SQ + V
Sbjct: 1594 NHLNQDIMHQQQDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQQMVSQPSIV-----T 1648
Query: 902 RNQDMS 907
R+ DM+
Sbjct: 1649 RSSDMT 1654
Score = 31.2 bits (69), Expect = 6.0
Identities = 87/447 (19%), Positives = 154/447 (34%), Gaps = 58/447 (12%)
Query: 574 QAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNM-PGGLPRQAYTQKTTQ--LEHK 630
QA+ ++ S S+L+ P +Q+ + TG + P Q + T + LE
Sbjct: 1154 QADIREVASKPSEASLLEGDPPFKSQIPKESGTGQAEATPNEFNSQGSIEATMERPLEKP 1213
Query: 631 SQMYQVEMNQGQSQGTVDQHLQFQKPS--HQVHFSKTDH-------LPKAHVQSLCGTRF 681
S ++ + Q + Q S + +H S H L Q+
Sbjct: 1214 SCSLGIKTSNASLQDSTSQPPSITSLSVNNLIHQSSISHPLASCAGLSPTSEQTTVPATV 1273
Query: 682 HFQQRADSQTEKLMSPVLKQHLNQQASET-----------EPFSN-SHLLQHKPHKQAAQ 729
+ + S + P L +Q+ T EP SH + K+A Q
Sbjct: 1274 NLTVSSSSYGSQPPGPSLMTEYSQEQLNTMTSTIPNSQIQEPLLKPSHESRKDSAKRAVQ 1333
Query: 730 TQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQR-------EGSFFGQTKVE 782
SS Q Q L++++ + +T P + +DQ + S V
Sbjct: 1334 DDLLLSSAKRQKHCQPAPLRLESMSLMSRT---PDTISDQTQMMVSQIPPNSSNSVVPVS 1390
Query: 783 ECFHGENQ---YSKSSEFETH-----NVQMGLEE--VQNINRRNSPYSQTMKSSACKIQV 832
HG+ + S+ F T VQ G + + + S + Q ++ V
Sbjct: 1391 NPAHGDGLTRLFPPSNNFVTPALRQTEVQCGSQPSVAEQQQTQASQHLQALQQHVPAQGV 1450
Query: 833 SCSNNTHLV-----SENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQE 887
S ++ HL + ++Q + + + HH+ ++V + +H
Sbjct: 1451 SHLHSNHLYIKQQQQQQQQQQQQQQQQQAGQLRERHHLYQMQHHVPHAESSVHSQPHNVH 1510
Query: 888 QKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQ 947
Q+ +Q K RN + G Q +QL+ Q +H DQ S T P Q
Sbjct: 1511 QQRTLQQEVQMQKKRNL-VQGTQTSQLSLQP---KHHGT-----DQSRSKTGQPHPHHQQ 1561
Query: 948 KHAALRWHLLQKQEQQQTQQPQTESCH 974
++ H Q ++ + P T H
Sbjct: 1562 MQQQMQQHFGSSQTEKSCENPSTSRNH 1588
Score = 31.2 bits (69), Expect = 6.0
Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 16/104 (15%)
Query: 909 QQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQEQQQTQQP 968
QQ Q +Q + H VP QG SH + H ++ Q+Q+QQQ QQ
Sbjct: 1429 QQQTQASQHLQALQQH-----VPAQGVSHLHS-------NHLYIKQQQQQQQQQQQQQQQ 1476
Query: 969 QTESCHSQMHRPIKVEPGCKPHA--CMHTAPPENKTWKKVTKQE 1010
Q + H +++ PHA +H + P N ++ +QE
Sbjct: 1477 QQAGQLRERHHLYQMQHHV-PHAESSVH-SQPHNVHQQRTLQQE 1518
>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
Length = 696
Score = 42.0 bits (97), Expect = 0.003
Identities = 91/472 (19%), Positives = 168/472 (35%), Gaps = 84/472 (17%)
Query: 572 FHQAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYTQKTTQLEHKS 631
+++ ++ L++ EA Q+Q +LS Q+ Y S + L ++ +LEHK
Sbjct: 33 YYELQTQLRKAEAVALKYQQHQESLSAQL-QVVYEHRSRLEKSLQKE-------RLEHKK 84
Query: 632 Q-----MYQVEMNQGQSQGTVDQHLQFQ--KPSHQVHFSKTDHLPKAHVQSLCGTR---- 680
+Y++E + ++G D + ++ HQ+ S+ + L K H R
Sbjct: 85 AKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQMLKSQHEELKKQHSDLEEEHRKQGE 144
Query: 681 -------------FHFQQRADSQTEKLMSPVLK-QHLNQQASETEPFSNSHLL----QHK 722
QQ + + KL V + N+Q + ++ L QHK
Sbjct: 145 DFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLREENRQLRKAHQDIHTQLQDVKQQHK 204
Query: 723 ----PHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQ 778
H+Q T S L Q Q + K ++ L P + + + Q
Sbjct: 205 NLLSEHEQLVVTLEDHKSALAA--AQTQVAEYKQLKDTLNRIPSLRKPDPAE-------Q 255
Query: 779 TKVEECFHGENQYSKSSEFETHNVQ---------MGLEEVQNINRRNSPYSQTMKSSACK 829
V + H Y+ + E T VQ E V Y+ T K + +
Sbjct: 256 QNVTQVAHSPQGYNTAREKPTREVQEVSRNNDVWQNHEAVPGRAEDTKLYAPTHKEAEFQ 315
Query: 830 IQ---VSCSNNTHLVSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQ 886
+ E++ + H + + + + ++ P + R ++EQ
Sbjct: 316 APPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEEHDPSPEEQDREWKEQ 375
Query: 887 EQKSQQASVLQGYKNRNQDMSGQQAA--------QLAQQRYLIHNHANVFPVPDQGGSHT 938
++ + A++L+G+ S + QL QQR + Q
Sbjct: 376 HEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQ----------QVEEAQ 425
Query: 939 QTPPQKDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQMHRPIKVEPGCKPH 990
Q ++ L+ HLL++QEQQQ Q + + R ++E G H
Sbjct: 426 QLREHQEALHQQRLQGHLLRQQEQQQQQVAR----EMALQRQAELEEGRPQH 473
Score = 34.7 bits (78), Expect = 0.54
Identities = 64/306 (20%), Positives = 115/306 (37%), Gaps = 46/306 (15%)
Query: 628 EHKSQMYQVEMNQ-GQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQR 686
EH+ + + EM Q GQ++ ++H P Q K H + L G
Sbjct: 338 EHRKALEEEEMEQVGQAEHLEEEH--DPSPEEQDREWKEQHEQREAANLLEGHARAEVYP 395
Query: 687 ADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQ 746
+ K SP +Q L QQ + + L+ H++A Q Q L Q +QQQQ
Sbjct: 396 SAKPMIKFQSPYEEQ-LEQQRLAVQQVEEAQQLRE--HQEALHQQRLQGHLLRQQEQQQQ 452
Query: 747 KL---------------QIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEECFHGENQY 791
++ + +++E++ Q + +ND + G E + +NQ+
Sbjct: 453 QVAREMALQRQAELEEGRPQHQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQH 512
Query: 792 SKSSEFETHNVQMGLEE---------------VQNINRRNSPYSQTMKSSACKIQVSCSN 836
+E + N E+ V++IN + P +Q QV N
Sbjct: 513 QDEAEGDPGNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREEN 572
Query: 837 NTHLVSENKEQTTHPELFAGNKTQNLHHMQY--FPNNVIPKQDLLHRCFQEQEQKSQQAS 894
L EN+EQ + K +N ++ N ++D + +QE+ ++ Q
Sbjct: 573 ---LPDENEEQKQ-----SNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQED 624
Query: 895 VLQGYK 900
+ + K
Sbjct: 625 LTEEKK 630
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 41.2 bits (95), Expect = 0.006
Identities = 54/220 (24%), Positives = 82/220 (37%), Gaps = 36/220 (16%)
Query: 552 LVPPTQHYLK--PGWIELKAPRFHQAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNS 609
LV PT+H + G++ +AP + + +R LQ P +S MT G
Sbjct: 1984 LVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQT---LQQTPMIST-MTPMSAQGV- 2038
Query: 610 NMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLP 669
QA + T L + Q Q + Q Q Q Q Q Q+ Q H +
Sbjct: 2039 --------QAGVRSTAILPEQQQQQQQQQQQQQQQ----QQQQQQQQQQQYHIRQQQQQQ 2086
Query: 670 KAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQ 729
Q QQ+ Q ++ +Q QQ + + Q P + Q
Sbjct: 2087 ILRQQQ--------QQQQQQQQQQ------QQQQQQQQQQQQQHQQQQQQQAAPPQPQPQ 2132
Query: 730 TQPS-QSSHLPQNQQQQQKLQIKNK--EEILQTFPHPQSN 766
+QP Q L Q QQQQQ + + +++ T P P +N
Sbjct: 2133 SQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPSTN 2172
Score = 40.0 bits (92), Expect = 0.013
Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 1/90 (1%)
Query: 684 QQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQ 743
QQ+ Q ++ +Q QQ +L+ + +Q Q Q Q Q QQ
Sbjct: 2053 QQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQ-QQQQQ 2111
Query: 744 QQQKLQIKNKEEILQTFPHPQSNNDQQREG 773
QQQ+ Q + +++ P PQS QR+G
Sbjct: 2112 QQQQHQQQQQQQAAPPQPQPQSQPQFQRQG 2141
Score = 38.1 bits (87), Expect = 0.049
Identities = 56/252 (22%), Positives = 95/252 (37%), Gaps = 18/252 (7%)
Query: 570 PRFHQAESHLKRNEASL--PSILQYQPNLSNQM-TSKQYTGNSNMPGGLPRQAYTQKTTQ 626
P+ + L++++ L S+ Q P+ S + TS+ YT + G
Sbjct: 1906 PQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVP 1965
Query: 627 LEHKSQMYQVEMNQGQSQGTVD--QHLQFQKPSHQVHFSKTDHLPKAHVQSLCGT-RFHF 683
+ SQ YQ + + VD +HLQ Q+PS VH + L T RF
Sbjct: 1966 PSYSSQPYQ-STHPSTNPTLVDPTRHLQ-QRPSGYVH-----QQAPTYGHGLTSTQRFSH 2018
Query: 684 QQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQN-- 741
Q + M+P+ Q + T Q + +Q Q Q Q Q
Sbjct: 2019 QTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYH 2078
Query: 742 ---QQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEECFHGENQYSKSSEFE 798
QQQQQ L+ + +++ Q Q QQ++ Q + ++ + Q +F+
Sbjct: 2079 IRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQ 2138
Query: 799 THNVQMGLEEVQ 810
+Q ++ Q
Sbjct: 2139 RQGLQQTQQQQQ 2150
Score = 36.6 bits (83), Expect = 0.14
Identities = 33/146 (22%), Positives = 55/146 (37%), Gaps = 27/146 (18%)
Query: 885 EQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQK 944
EQ+Q+ QQ + + Q QQ Q QQ+Y I Q+
Sbjct: 2050 EQQQQQQQ-------QQQQQQQQQQQQQQQQQQQYHIR--------------------QQ 2082
Query: 945 DTQKHAALRWHLLQKQEQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWK 1004
Q+ + Q+Q+QQQ QQ Q + Q H+ + + P + P +
Sbjct: 2083 QQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGL 2142
Query: 1005 KVTKQENPPASCDNVQQKSIIETMEQ 1030
+ T+Q+ A+ Q+ + T Q
Sbjct: 2143 QQTQQQQQTAALVRQLQQQLSNTQPQ 2168
>gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]
Length = 1424
Score = 40.8 bits (94), Expect = 0.008
Identities = 180/845 (21%), Positives = 291/845 (34%), Gaps = 159/845 (18%)
Query: 55 HSFKSYYGIPCMKGSQNSRVSPDFTQESRGYSKCLQNG---GIKRTVSEPS--LSGLLQI 109
H F G+ S + + F+ S + + G + T+S P L +
Sbjct: 495 HQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAISEGVGTSLLSTLSSPGPKLDNSPNM 554
Query: 110 KKLKQDQKANGERRN-FGVSQERNPGESS--QPNVSD-LSDKKESVSSVAQENAVKDFTS 165
+ + +N + ++ G ++NP ESS Q N D LSDK+ SSV +
Sbjct: 555 NITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGPLE 614
Query: 166 FSTHN-------CSGPENPELQILNEQEGKSANYHDKNIVLLKNKAVLMPNGATVSAS-- 216
H CS + + N S + +V P+G + S S
Sbjct: 615 SKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKE--------SSVSVTSPSGVSSSTSGG 666
Query: 217 --SVEHTHGELLEKTLSQYYPDCVSIAVQKTTSHINAINSQATNELSCEITHPSHTSGQI 274
S + HG LL++ + + + + + I ++AT + + IT S G +
Sbjct: 667 VSSTSNMHGSLLQEKHRILHK---LLQNGNSPAEVAKITAEATGKDTSSIT--SCGDGNV 721
Query: 275 NSAQTSNSELPPKPA---AVVSEACDADDADNASKLAAMLNTCSFQKPEQLQQQKSVFEI 331
+L PK A++ D DD +A S + Q++ +
Sbjct: 722 ----VKQEQLSPKKKENNALLRYLLDRDDPSDA---------LSKELQPQVEGVDNKMSQ 768
Query: 332 CPS---PAENNIQGTTKLASGEEFCSGSSSNLQAPGG---SSERYLKQNEMNGAYF--KQ 383
C S P+ + + E SG NL A G SS+ Y NG++ KQ
Sbjct: 769 CTSSTIPSSSQEKDPKIKTETSEEGSGDLDNLDAILGDLTSSDFYNNSISSNGSHLGTKQ 828
Query: 384 ------SSVFTKDSFSATTTPPP-------PSQLLLSPPPPLPQVPQLPSEGKSTLNGG- 429
+S+ K S S + PP S + + PP+ + P K + GG
Sbjct: 829 QVFQGTNSLGLKSSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGN 888
Query: 430 --VLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERPQNNCVNR 487
+++ +Y + R V + P + PN P S N
Sbjct: 889 PRMMDSQENYGSSMGGPN-RNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNT 947
Query: 488 NDIQTAGTMTVPLCSEKTRPMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEILKGRDKE 547
+ + A ++P T P+ + I G+ LQ QQ+++ + EI G
Sbjct: 948 SLPRPALGGSIP-----TLPLRSN-----SIPGARPVLQQQ-QQMLQMRPGEIPMGMGAN 996
Query: 548 QTRDLVPPTQHYLKP-GWIELKAPRFHQAESHLKRNE----ASLPSILQYQPN------- 595
Q P G + ++ L RN PS L+ Q +
Sbjct: 997 PYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQ 1056
Query: 596 LSNQMTSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQ-----VEMNQ-----GQS-- 643
L +++ TG + L + LE K +Q V M+Q GQ+
Sbjct: 1057 LHTLLSNTDATGLEEIDRALGIPELVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYP 1116
Query: 644 -QGTVDQ---HLQFQKPS---------HQVHFSKTDHLPKAHV----------------Q 674
QG Q HLQ Q PS Q +F P+A++ Q
Sbjct: 1117 AQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQ 1176
Query: 675 SLCGTRFHFQQRADSQTEKLMSP------VLKQHLNQQASETEPFSNS------------ 716
L G +F Q R + K+ +P V++ + Q S + F N+
Sbjct: 1177 RLQGQQFLNQSRQALEL-KMENPTAGGAAVMRPMMQPQVSSQQGFLNAQMVAQRSRELLS 1235
Query: 717 -HLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTF-PHPQSNNDQQREGS 774
H Q + Q Q Q Q QQQQQ+ Q + +++ Q F P P +G
Sbjct: 1236 HHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGL 1295
Query: 775 FFGQT 779
G T
Sbjct: 1296 LAGPT 1300
>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
Length = 2382
Score = 40.8 bits (94), Expect = 0.008
Identities = 60/281 (21%), Positives = 101/281 (35%), Gaps = 38/281 (13%)
Query: 240 IAVQKTTSHINAINSQATNELSCEITHPSHTSGQINSAQTSNSELP-PKPAAVVSEACDA 298
+++ T+ + S + +S +PS T +++ ++ P PKP AVVS+
Sbjct: 1422 VSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAG 1481
Query: 299 DDADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKL-------ASGEE 351
A+ + T QL Q S P+ AE + L +G
Sbjct: 1482 STTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLA 1541
Query: 352 FCSGSSSNLQAPGGSSERYLKQNEMNGAYFKQSSVFTKDSFSATTTPPPPSQLLLSPPPP 411
F + S+ +PG Y+ Q S + +TP P + P
Sbjct: 1542 FSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVI--------ASTPILPQAAGPTSTPL 1593
Query: 412 LPQVPQLPSEGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPN-PSTHVC 470
LPQVP +P + +N +++ I +P+ P+ PN P TH
Sbjct: 1594 LPQVPSIPPLVQPV---------------ANVPAVQQTLIHSQPQ--PALLPNQPHTH-- 1634
Query: 471 SPSPMLSERPQNNCVNRNDIQTAGTMTVPLCSEKTRPMSEH 511
P + Q +DI+T L SE + ++H
Sbjct: 1635 --CPEVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQH 1673
>gi|120953251 neuron navigator 3 [Homo sapiens]
Length = 2363
Score = 40.8 bits (94), Expect = 0.008
Identities = 79/336 (23%), Positives = 118/336 (35%), Gaps = 68/336 (20%)
Query: 232 QYYPDCVSIAVQKTTSHINAINSQATNE------LSCEITHPSHTSGQINSAQTSNSELP 285
QYY V + + T + + SQA + L+ S+ SG I ++Q + LP
Sbjct: 191 QYYQSLVELQQRVTHASPPSEASQAKTQQDMQSSLAARYATQSNHSG-IATSQKKPTRLP 249
Query: 286 -PKPAAVVSEACDADDADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTT 344
P + A N ++ + N+ KP P+ A N + ++
Sbjct: 250 GPSRVPAAGSSSKVQGASNLNRRSQSFNSIDKNKP-------------PNYANGNEKDSS 296
Query: 345 KLASGEEFCSGSSSNLQAPGG------------SSERYLKQNEMNGAYFKQSSVFTKDSF 392
K G + SG + N+Q P S+ + + MN + S++ T
Sbjct: 297 K---GPQSSSGVNGNVQPPSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQS 353
Query: 393 SATTTPPPPSQLLLSPPPPLPQVPQLPSEGKSTLNGGVLEEHHHYPNQSNTTLLREVKIE 452
S T+P P S L PP V PS KS L L + T L
Sbjct: 354 STATSPTPSSDRL--KPPVSEGVKTAPSGQKSMLEKFKLV-------NARTAL------- 397
Query: 453 GKPEAPPSQSPNPSTHVCSPSPMLSERPQNNCVNRNDIQTAGTMTVPLCSEKTRPMSEHL 512
+P PPS P+ SE + N T + P S K
Sbjct: 398 -RPPQPPSSGPSDGG---KDDDAFSESGEMEGFNSGLNSGGSTNSSPKVSPKLA------ 447
Query: 513 KHNPPIFGSSGELQDNCQQLMRNKEQEILKGRDKEQ 548
PP GS N + L++ KE+E K RDK +
Sbjct: 448 ---PPKAGSKN--LSNKKSLLQPKEKE-EKNRDKNK 477
>gi|49472835 bridging integrator 2 [Homo sapiens]
Length = 565
Score = 40.4 bits (93), Expect = 0.010
Identities = 73/350 (20%), Positives = 128/350 (36%), Gaps = 35/350 (10%)
Query: 216 SSVEHTHGELLEKTLSQYYPDCVSIAVQKTTSHINAINSQATNELSCEITHPSHTSGQIN 275
S + H E++ K Q+ + ++S + + S + S TS
Sbjct: 225 SKLNHNLYEVMSKLEKQHSNKVFVVKGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTL 284
Query: 276 SAQTSNSELPPKPAAVVSEACDADDADNASKLAAMLNTCSFQKP---EQLQQQKSVFEIC 332
S ++ + + +A A DA ++ S++ +L +K ++ C
Sbjct: 285 SLKSESESV----SATEDLAPDAAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEPLPAC 340
Query: 333 PSPAENNIQGTTKLASGEEFCSGSSSNLQAPGGS-----------SERYLKQNEMNGAYF 381
PA+ TT+ A +E SS+ +PGG+ +E L+ +
Sbjct: 341 NGPAQAQPSPTTERAKSQEEVLPSSTT-PSPGGALSPSGQPSSSATEVVLRTRTASEGSE 399
Query: 382 KQSSVFTKDSFSATTTPPPPSQLLLSPPPPLPQVPQLPSEGKSTLNGGVLEEHHHYPNQS 441
+ + SA + PPP + SP P +P P T +GG +
Sbjct: 400 QPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSP-----TASGGGSPTSPRASLGT 454
Query: 442 NTTLLREVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERPQNNCVNRNDIQTAGT-MTVPL 500
T R +E P P + P V +P +E N N ++ T+ T MT +
Sbjct: 455 GTASPR-TSLEVSPNPEPPEKP-----VRTPEAKENENIHNQ--NPEELCTSPTLMTSQV 506
Query: 501 CSE--KTRPMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEILKGRDKEQ 548
SE + + M + K N I +S E QD Q M + + +E+
Sbjct: 507 ASEPGEAKKMEDKEKDNKLISANSSEGQDQLQVSMVPENNNLTAPEPQEE 556
>gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a
[Homo sapiens]
Length = 1130
Score = 40.0 bits (92), Expect = 0.013
Identities = 65/295 (22%), Positives = 107/295 (36%), Gaps = 31/295 (10%)
Query: 267 PSHTSGQINSAQTSNSELPPKPAAVVSEACDADDADNASKLAAMLNTCSFQKPEQLQQQK 326
P +G+ S Q + + P P V AD+ ++ ++ P+ L++Q
Sbjct: 763 PRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQV 822
Query: 327 SVFEICPSPAENNIQGTTKL---ASGEEFCSGSSSNLQAPGGSSERYLKQNEMNG-AYFK 382
+V P + + L A+ E S + APGG+S+ +++ + +
Sbjct: 823 TVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSS 882
Query: 383 QSSVFTKDSFSAT--TTPPPPSQLLLSPPPPLPQVPQLPSEGKSTLNG--------GVLE 432
+S K S PPPP+ Q P + G++ L +
Sbjct: 883 ESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVN 942
Query: 433 EHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERPQNNCVNRNDIQT 492
P+Q L + V P P QS PS SP+P+ S P + D Q
Sbjct: 943 SDAAKPSQPGEGLKKPVL----PATPKPQSAKPSGTPISPAPVPSTLPSASSALAGD-QP 997
Query: 493 AGTMTVPLCSEKTRPMSEHLKHNPPIFGSSGELQDN---------CQQLMRNKEQ 538
+ T +PL S + +S PP +SG + C + RN EQ
Sbjct: 998 SSTAFIPLISTR---VSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQ 1049
>gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b
[Homo sapiens]
Length = 1149
Score = 40.0 bits (92), Expect = 0.013
Identities = 65/295 (22%), Positives = 107/295 (36%), Gaps = 31/295 (10%)
Query: 267 PSHTSGQINSAQTSNSELPPKPAAVVSEACDADDADNASKLAAMLNTCSFQKPEQLQQQK 326
P +G+ S Q + + P P V AD+ ++ ++ P+ L++Q
Sbjct: 782 PRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKDIMESSPGSSPPNLTPKPLRRQV 841
Query: 327 SVFEICPSPAENNIQGTTKL---ASGEEFCSGSSSNLQAPGGSSERYLKQNEMNG-AYFK 382
+V P + + L A+ E S + APGG+S+ +++ + +
Sbjct: 842 TVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSS 901
Query: 383 QSSVFTKDSFSAT--TTPPPPSQLLLSPPPPLPQVPQLPSEGKSTLNG--------GVLE 432
+S K S PPPP+ Q P + G++ L +
Sbjct: 902 ESPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVN 961
Query: 433 EHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERPQNNCVNRNDIQT 492
P+Q L + V P P QS PS SP+P+ S P + D Q
Sbjct: 962 SDAAKPSQPGEGLKKPVL----PATPKPQSAKPSGTPISPAPVPSTLPSASSALAGD-QP 1016
Query: 493 AGTMTVPLCSEKTRPMSEHLKHNPPIFGSSGELQDN---------CQQLMRNKEQ 538
+ T +PL S + +S PP +SG + C + RN EQ
Sbjct: 1017 SSTAFIPLISTR---VSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQ 1068
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 40.0 bits (92), Expect = 0.013
Identities = 37/144 (25%), Positives = 56/144 (38%), Gaps = 15/144 (10%)
Query: 635 QVEMNQGQSQGTVD--QHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQRADSQTE 692
Q + Q Q QG++ HLQ SH PK Q + + QQ+ Q +
Sbjct: 3858 QQQQQQHQQQGSMAGLSHLQQSLMSHSGQ-------PKLSAQPMGSLQQLQQQQQLQQQQ 3910
Query: 693 KLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKN 752
+L +Q QQ + + Q +Q Q Q Q Q QQQQQ+ Q +
Sbjct: 3911 QLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQ 3970
Query: 753 KEEIL------QTFPHPQSNNDQQ 770
+++ + +T PQ QQ
Sbjct: 3971 QQQQMGLLNQSRTLLSPQQQQQQQ 3994
Score = 35.0 bits (79), Expect = 0.42
Identities = 37/169 (21%), Positives = 62/169 (36%), Gaps = 6/169 (3%)
Query: 612 PGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKA 671
P G RQ ++ L Q + G T Q Q Q+ Q + HL ++
Sbjct: 3820 PQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQS 3879
Query: 672 HVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQ 731
+ S G Q + +Q + + +Q QQ + + L Q + +Q Q
Sbjct: 3880 -LMSHSG-----QPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQ 3933
Query: 732 PSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTK 780
Q L Q QQQQ + Q + ++ Q QQ++ Q++
Sbjct: 3934 QQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSR 3982
Score = 33.5 bits (75), Expect = 1.2
Identities = 40/170 (23%), Positives = 65/170 (38%), Gaps = 18/170 (10%)
Query: 635 QVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHV----QSLCGTRF----HFQQR 686
QV + Q Q G + Q P QV +++ L + Q L G R QQ+
Sbjct: 3806 QVAVLQQQHPGALGP----QGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQ 3861
Query: 687 ADSQTEKLMSPV------LKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQ 740
Q + M+ + L H Q +P + LQ + Q Q Q Q
Sbjct: 3862 QQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQ 3921
Query: 741 NQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEECFHGENQ 790
QQQ Q+ Q++ +++ Q Q QQ++ Q + ++ F + Q
Sbjct: 3922 QQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQ 3971
Score = 32.3 bits (72), Expect = 2.7
Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 19/94 (20%)
Query: 884 QEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQ 943
Q+Q+Q QQ + Q + + Q Q QL QQ+ Q Q
Sbjct: 3901 QQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQ-------------------QQQLQ 3941
Query: 944 KDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQM 977
+ Q+ + LQ+Q+QQQ QQ Q + QM
Sbjct: 3942 QQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQM 3975
Score = 31.6 bits (70), Expect = 4.6
Identities = 39/129 (30%), Positives = 53/129 (41%), Gaps = 28/129 (21%)
Query: 397 TPPPPSQLLLSPPP------PLPQVPQL--PSEGKSTLNGGVLEEHHHYPNQSNTTLLRE 448
T PPP LSPPP PLP+ L P E +S L+ E P +S+
Sbjct: 458 TSPPPEASRLSPPPEELPASPLPEALHLSRPLE-ESPLSPPPEESPLSPPPESSPF---- 512
Query: 449 VKIEGKPEAPPSQSPNPSTHVCSPSPMLSERPQNNCVNRNDIQTAGTMTVPLCSEKTRPM 508
+E P +PP +SP PS + +P LS P+ A ++ P P
Sbjct: 513 SPLEESPLSPPEESP-PSPALETP---LSPPPE-----------ASPLSPPFEESPLSPP 557
Query: 509 SEHLKHNPP 517
E L +PP
Sbjct: 558 PEELPTSPP 566
Score = 31.2 bits (69), Expect = 6.0
Identities = 30/101 (29%), Positives = 39/101 (38%), Gaps = 13/101 (12%)
Query: 397 TPPPPSQLLLSPPP------PLPQVPQLPSEGKSTLNGGVLEEHHHYPNQSNTTLLREVK 450
T PPP LSPPP P P+ + +L LEE P L +
Sbjct: 680 TSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSE 739
Query: 451 ---IEGKPEAPPSQSPNPSTHVCSP---SPMLSERPQNNCV 485
+ +PE P SP P SP P LS +P+ C+
Sbjct: 740 GPHLSPRPE-EPHLSPRPEEPHLSPQAEEPHLSPQPEEPCL 779
Score = 31.2 bits (69), Expect = 6.0
Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 24/111 (21%)
Query: 884 QEQEQKSQQASVLQGYKNRNQDM---SGQ---------QAAQLAQQRYLIHNHANVFPVP 931
Q+Q+Q+ QQ + G + Q + SGQ QL QQ+ L
Sbjct: 3858 QQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQL----------- 3906
Query: 932 DQGGSHTQTPPQKDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQMHRPIK 982
Q Q Q+ Q+ L+ LQ+Q+QQQ Q Q + Q + ++
Sbjct: 3907 -QQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQ 3956
Score = 31.2 bits (69), Expect = 6.0
Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 705 QQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQ 764
QQ + + LQ + +Q Q Q Q L QQQQQ+ Q++ +++ Q
Sbjct: 3898 QQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQL---QQQQQQQQLQQQQQQQLQQQQQQ 3954
Query: 765 SNNDQQREGSFFGQTKVEE 783
QQ++ F Q + ++
Sbjct: 3955 LQQQQQQQQQQFQQQQQQQ 3973
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 40.0 bits (92), Expect = 0.013
Identities = 59/246 (23%), Positives = 90/246 (36%), Gaps = 30/246 (12%)
Query: 533 MRNKEQEILKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAESHLKRNEASLPSILQY 592
++ E K + K + D +P T+ + P + P+ Q + + P IL
Sbjct: 337 VKASEAAAKKTQPKARLTDPIPTTETSIAPR----QRPKAGQTQPN--------PGILPI 384
Query: 593 QPNLSNQMTSK-----QYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTV 647
QP L+ + + Q G+SN PG L + Q Q + Q + Q Q+ T
Sbjct: 385 QPALTPRKRATVQPPPQAAGSSNQPGLLA--SVPQPKPQAPPSQPLPQTQAKQPQAPPTP 442
Query: 648 DQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQA 707
Q Q T H Q L F QQ+ Q QQ
Sbjct: 443 QQTPSTQAQGLPAQAQATPQ----HQQQL----FLKQQQQQQQPPPAQQQPAGTFYQQQQ 494
Query: 708 SETEPFSNSHLLQHKPH--KQAAQTQPSQSSHLPQN-QQQQQKLQIKNKEEILQTFPHPQ 764
++T+ F H +P + +Q L QN QQQQ+ Q + +++ L T H Q
Sbjct: 495 AQTQQFQAVHPATQQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQ 554
Query: 765 SNNDQQ 770
QQ
Sbjct: 555 QLMTQQ 560
Score = 34.3 bits (77), Expect = 0.71
Identities = 40/164 (24%), Positives = 61/164 (37%), Gaps = 10/164 (6%)
Query: 609 SNMPGGLPRQAYT----QKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSK 664
S GLP QA Q+ L+ + Q Q Q Q GT Q Q Q Q
Sbjct: 447 STQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPA 506
Query: 665 TDH--LPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHK 722
T + + V S G++ Q Q ++ +Q L + + + LQ K
Sbjct: 507 TQQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQK 566
Query: 723 PHKQAAQTQPSQSSHLPQNQQQQQ---KLQIKNKEEILQTFPHP 763
P A Q Q + PQ Q+ + ++ + ++ QT P P
Sbjct: 567 PTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQPKV-QTTPPP 609
Score = 32.0 bits (71), Expect = 3.5
Identities = 28/93 (30%), Positives = 37/93 (39%), Gaps = 13/93 (13%)
Query: 884 QEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQ 943
Q+Q +QQ Y+ + QA A Q+ I FPV QGGS Q
Sbjct: 475 QQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQPAIAQ----FPVVSQGGSQQQLMQN 530
Query: 944 KDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQ 976
Q+ Q+Q+QQQ QQ + H Q
Sbjct: 531 FYQQQ---------QQQQQQQQQQQLATALHQQ 554
Score = 31.6 bits (70), Expect = 4.6
Identities = 52/220 (23%), Positives = 85/220 (38%), Gaps = 22/220 (10%)
Query: 720 QHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFF--- 776
Q P QA Q P+Q+ PQ+QQQ L +K +++ Q P P QQ G+F+
Sbjct: 443 QQTPSTQA-QGLPAQAQATPQHQQQ---LFLKQQQQ--QQQPPPA---QQQPAGTFYQQQ 493
Query: 777 -GQTKVEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCS 835
QT+ + H Q ++F V G + Q + Q + + +
Sbjct: 494 QAQTQQFQAVHPATQQPAIAQFPV--VSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATAL 551
Query: 836 NNTHLVSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQA-- 893
+ L+++ P + AG + Q P P Q+ + Q+ K Q
Sbjct: 552 HQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQP---APAQEPAIQAPVRQQPKVQTTPP 608
Query: 894 SVLQGYKNRNQDMSGQQAAQLAQQRYLIHN--HANVFPVP 931
+QG K + Q A R ++ + H+ VF VP
Sbjct: 609 PAVQGQKVGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVP 648
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 39.7 bits (91), Expect = 0.017
Identities = 56/251 (22%), Positives = 100/251 (39%), Gaps = 20/251 (7%)
Query: 534 RNKEQEILKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAESHLKRNEASLPSILQYQ 593
RN+ QE+L R+KEQ +V + +E + HQ E L+ L
Sbjct: 451 RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL------- 503
Query: 594 PNLSNQMTSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQF 653
T +Q ++N L T QL+ QM + + Q DQ Q
Sbjct: 504 ------TTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILN--DQLKQV 555
Query: 654 QKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHL-NQQASETEP 712
Q+ S +H L +A +++ R H + + D ++ S + + + N Q E
Sbjct: 556 QQNS--LHRDSLVTLKRA-LEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELRE 612
Query: 713 FSNSHLLQHKPHKQAAQ-TQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQR 771
N LQ + +A + Q Q + + ++Q+++ Q + +E Q H Q ++ QR
Sbjct: 613 IHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQR 672
Query: 772 EGSFFGQTKVE 782
+ K++
Sbjct: 673 PRKLHEEEKLK 683
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 39.7 bits (91), Expect = 0.017
Identities = 56/251 (22%), Positives = 100/251 (39%), Gaps = 20/251 (7%)
Query: 534 RNKEQEILKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAESHLKRNEASLPSILQYQ 593
RN+ QE+L R+KEQ +V + +E + HQ E L+ L
Sbjct: 451 RNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL------- 503
Query: 594 PNLSNQMTSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQF 653
T +Q ++N L T QL+ QM + + Q DQ Q
Sbjct: 504 ------TTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILN--DQLKQV 555
Query: 654 QKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHL-NQQASETEP 712
Q+ S +H L +A +++ R H + + D ++ S + + + N Q E
Sbjct: 556 QQNS--LHRDSLVTLKRA-LEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELRE 612
Query: 713 FSNSHLLQHKPHKQAAQ-TQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQR 771
N LQ + +A + Q Q + + ++Q+++ Q + +E Q H Q ++ QR
Sbjct: 613 IHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQR 672
Query: 772 EGSFFGQTKVE 782
+ K++
Sbjct: 673 PRKLHEEEKLK 683
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 39.7 bits (91), Expect = 0.017
Identities = 102/546 (18%), Positives = 175/546 (32%), Gaps = 86/546 (15%)
Query: 238 VSIAVQKTTSHINAINSQATNELSCEITHPSHTSGQINSAQTSNSELPPK-PAAVVSEAC 296
+S + + +++S L T S G +++ N E P VS+
Sbjct: 1483 ISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHS 1542
Query: 297 DADDADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGEEFCSGS 356
S L ++ +T + IC + + + L+S S
Sbjct: 1543 QQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSS 1602
Query: 357 SSNLQ--APGGSSERYLKQNEMNGAY-----FKQSSVFTKDSFSATTTPPPPSQLLLSPP 409
Q A GSS ++Q+ + A QS V + + PPPP PP
Sbjct: 1603 CVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPP 1662
Query: 410 PPLPQ-VPQLPSEGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPS-- 466
PP PQ PQ P P Q + + P PP Q P S
Sbjct: 1663 PPQPQPAPQPPP-----------------PQQQPQQQPQPQPQQPPPPPPPQQQPPLSQC 1705
Query: 467 --THVCSPSPMLSERPQNNCVNRNDI--------------QTAGTMTVPLCSEKTR---- 506
+ +P+PM+ E P++ I Q + T ++ + T
Sbjct: 1706 SMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMD 1765
Query: 507 PMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEILKGRDKEQTRDLVPPTQHYLKPGWIE 566
P + H+P + + + + L + L G + Q PP
Sbjct: 1766 PHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPP----------N 1815
Query: 567 LKAPRFHQAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYTQKTTQ 626
L + + L+ N ++ + + L QM K + + LP A
Sbjct: 1816 LASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPSAA------- 1868
Query: 627 LEHKSQMY-----QVEMNQGQSQGTVDQHLQ-----FQKPSHQVHFSKTDHLPKAH---- 672
H+ Q+Y V M G V + + P++ V+ + L +
Sbjct: 1869 -AHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLNAMNSYRM 1927
Query: 673 VQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQP 732
Q + + +H +QT + + + QA +P +Q PH T P
Sbjct: 1928 TQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQP------MQPNPHGNMMYTGP 1981
Query: 733 SQSSHL 738
S S++
Sbjct: 1982 SHHSYM 1987
Score = 31.2 bits (69), Expect = 6.0
Identities = 38/215 (17%), Positives = 77/215 (35%), Gaps = 17/215 (7%)
Query: 707 ASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSN 766
AS + ++ +P + + +P S Q++++QQ+L+ EE N
Sbjct: 1252 ASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQN 1311
Query: 767 NDQQREGSFFGQTKVEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSS 826
+D + G + + E Q ++ E VQ + N+ + ++
Sbjct: 1312 DDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDA-NMQKSREKIKDKEETE 1370
Query: 827 ACKIQVSCSNNTHLVSE---------NKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQD 877
+ S++T +VSE ++ T EL + + + H + V Q
Sbjct: 1371 LDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQS 1430
Query: 878 LLHR-------CFQEQEQKSQQASVLQGYKNRNQD 905
L +Q+ E+ LQ Y ++D
Sbjct: 1431 LTQEESSEHEGAYQDCEETLAACQTLQSYTQADED 1465
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 39.7 bits (91), Expect = 0.017
Identities = 102/546 (18%), Positives = 175/546 (32%), Gaps = 86/546 (15%)
Query: 238 VSIAVQKTTSHINAINSQATNELSCEITHPSHTSGQINSAQTSNSELPPK-PAAVVSEAC 296
+S + + +++S L T S G +++ N E P VS+
Sbjct: 1483 ISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHS 1542
Query: 297 DADDADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGEEFCSGS 356
S L ++ +T + IC + + + L+S S
Sbjct: 1543 QQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSS 1602
Query: 357 SSNLQ--APGGSSERYLKQNEMNGAY-----FKQSSVFTKDSFSATTTPPPPSQLLLSPP 409
Q A GSS ++Q+ + A QS V + + PPPP PP
Sbjct: 1603 CVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPP 1662
Query: 410 PPLPQ-VPQLPSEGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPS-- 466
PP PQ PQ P P Q + + P PP Q P S
Sbjct: 1663 PPQPQPAPQPPP-----------------PQQQPQQQPQPQPQQPPPPPPPQQQPPLSQC 1705
Query: 467 --THVCSPSPMLSERPQNNCVNRNDI--------------QTAGTMTVPLCSEKTR---- 506
+ +P+PM+ E P++ I Q + T ++ + T
Sbjct: 1706 SMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMD 1765
Query: 507 PMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEILKGRDKEQTRDLVPPTQHYLKPGWIE 566
P + H+P + + + + L + L G + Q PP
Sbjct: 1766 PHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPP----------N 1815
Query: 567 LKAPRFHQAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYTQKTTQ 626
L + + L+ N ++ + + L QM K + + LP A
Sbjct: 1816 LASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPSAA------- 1868
Query: 627 LEHKSQMY-----QVEMNQGQSQGTVDQHLQ-----FQKPSHQVHFSKTDHLPKAH---- 672
H+ Q+Y V M G V + + P++ V+ + L +
Sbjct: 1869 -AHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLNAMNSYRM 1927
Query: 673 VQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQP 732
Q + + +H +QT + + + QA +P +Q PH T P
Sbjct: 1928 TQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQP------MQPNPHGNMMYTGP 1981
Query: 733 SQSSHL 738
S S++
Sbjct: 1982 SHHSYM 1987
Score = 31.2 bits (69), Expect = 6.0
Identities = 38/215 (17%), Positives = 77/215 (35%), Gaps = 17/215 (7%)
Query: 707 ASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSN 766
AS + ++ +P + + +P S Q++++QQ+L+ EE N
Sbjct: 1252 ASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQN 1311
Query: 767 NDQQREGSFFGQTKVEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSS 826
+D + G + + E Q ++ E VQ + N+ + ++
Sbjct: 1312 DDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDA-NMQKSREKIKDKEETE 1370
Query: 827 ACKIQVSCSNNTHLVSE---------NKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQD 877
+ S++T +VSE ++ T EL + + + H + V Q
Sbjct: 1371 LDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQS 1430
Query: 878 LLHR-------CFQEQEQKSQQASVLQGYKNRNQD 905
L +Q+ E+ LQ Y ++D
Sbjct: 1431 LTQEESSEHEGAYQDCEETLAACQTLQSYTQADED 1465
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 39.7 bits (91), Expect = 0.017
Identities = 102/546 (18%), Positives = 175/546 (32%), Gaps = 86/546 (15%)
Query: 238 VSIAVQKTTSHINAINSQATNELSCEITHPSHTSGQINSAQTSNSELPPK-PAAVVSEAC 296
+S + + +++S L T S G +++ N E P VS+
Sbjct: 1483 ISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQGSLSAPSMQNMETSPMMDVPSVSDHS 1542
Query: 297 DADDADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGEEFCSGS 356
S L ++ +T + IC + + + L+S S
Sbjct: 1543 QQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNSSSQSSCSYGGLSSSSSLTQSS 1602
Query: 357 SSNLQ--APGGSSERYLKQNEMNGAY-----FKQSSVFTKDSFSATTTPPPPSQLLLSPP 409
Q A GSS ++Q+ + A QS V + + PPPP PP
Sbjct: 1603 CVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPPSNQQQQPPPPPPQQPQPP 1662
Query: 410 PPLPQ-VPQLPSEGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPS-- 466
PP PQ PQ P P Q + + P PP Q P S
Sbjct: 1663 PPQPQPAPQPPP-----------------PQQQPQQQPQPQPQQPPPPPPPQQQPPLSQC 1705
Query: 467 --THVCSPSPMLSERPQNNCVNRNDI--------------QTAGTMTVPLCSEKTR---- 506
+ +P+PM+ E P++ I Q + T ++ + T
Sbjct: 1706 SMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMD 1765
Query: 507 PMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEILKGRDKEQTRDLVPPTQHYLKPGWIE 566
P + H+P + + + + L + L G + Q PP
Sbjct: 1766 PHAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATMTPPP----------N 1815
Query: 567 LKAPRFHQAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYTQKTTQ 626
L + + L+ N ++ + + L QM K + + LP A
Sbjct: 1816 LASTTMNLTSPLLQCNMSATNIGIPHTQRLQGQMPVKGHISIRSKSAPLPSAA------- 1868
Query: 627 LEHKSQMY-----QVEMNQGQSQGTVDQHLQ-----FQKPSHQVHFSKTDHLPKAH---- 672
H+ Q+Y V M G V + + P++ V+ + L +
Sbjct: 1869 -AHQQQLYGRSPSAVAMQAGPRALAVQRGMNMGVNLMPTPAYNVNSMNMNTLNAMNSYRM 1927
Query: 673 VQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQP 732
Q + + +H +QT + + + QA +P +Q PH T P
Sbjct: 1928 TQPMMNSSYHSNPAYMNQTAQYPMQMQMGMMGSQAYTQQP------MQPNPHGNMMYTGP 1981
Query: 733 SQSSHL 738
S S++
Sbjct: 1982 SHHSYM 1987
Score = 31.2 bits (69), Expect = 6.0
Identities = 38/215 (17%), Positives = 77/215 (35%), Gaps = 17/215 (7%)
Query: 707 ASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSN 766
AS + ++ +P + + +P S Q++++QQ+L+ EE N
Sbjct: 1252 ASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQN 1311
Query: 767 NDQQREGSFFGQTKVEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSS 826
+D + G + + E Q ++ E VQ + N+ + ++
Sbjct: 1312 DDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDA-NMQKSREKIKDKEETE 1370
Query: 827 ACKIQVSCSNNTHLVSE---------NKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQD 877
+ S++T +VSE ++ T EL + + + H + V Q
Sbjct: 1371 LDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQS 1430
Query: 878 LLHR-------CFQEQEQKSQQASVLQGYKNRNQD 905
L +Q+ E+ LQ Y ++D
Sbjct: 1431 LTQEESSEHEGAYQDCEETLAACQTLQSYTQADED 1465
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 39.3 bits (90), Expect = 0.022
Identities = 70/371 (18%), Positives = 134/371 (36%), Gaps = 41/371 (11%)
Query: 622 QKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHVQ----SLC 677
Q+ Q + + Q+E GQ + Q + + + K + L + Q L
Sbjct: 115 QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELW 174
Query: 678 GTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSH 737
R +Q+R + + E+ K H ++ + E LL+ + K + Q +
Sbjct: 175 RQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELR-RKGREEKQQQRRER 233
Query: 738 LPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEECFHGENQYSKSSEF 797
+ Q++++ + + +E +L+ + QR+ Q + E+ E Q +
Sbjct: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQREL--QEEEEQLRKLERQELRRERQ 291
Query: 798 ETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHLVSENKEQTTHPELFAGN 857
E Q L Q + R+ + + E +EQ E
Sbjct: 292 EEEQQQQRLRREQQLRRKQEEERREQQE-----------------ERREQQERREQQEER 334
Query: 858 KTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQ 917
+ Q L Q +++ R QE+E++ QQ Q + R Q + +Q QL ++
Sbjct: 335 REQQLRREQE------ERREQQLRREQEEERREQQLRREQEEERREQQLRREQ--QLRRE 386
Query: 918 RYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQM 977
+ L Q Q ++ ++ LR Q + +QQ ++ Q E H Q
Sbjct: 387 QQLRREQ--------QLRREQQLRREQQLRREQQLRREQ-QLRREQQLRREQEEERHEQK 437
Query: 978 HRPIKVEPGCK 988
H + E K
Sbjct: 438 HEQERREQRLK 448
Score = 37.0 bits (84), Expect = 0.11
Identities = 80/489 (16%), Positives = 180/489 (36%), Gaps = 44/489 (8%)
Query: 530 QQLMRNKEQEILKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAESHLKRNEASLPSI 589
QQL R +E+E + +E+ R+ + + +L+ + + E L+R +
Sbjct: 304 QQLRRKQEEE--RREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERRE 361
Query: 590 LQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQ 649
Q + + +Q L R+ ++ QL + Q+ + + + + Q +Q
Sbjct: 362 QQLRREQEEERREQQLRREQQ----LRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 417
Query: 650 HLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQ-------RADSQTEKLMSPVLKQH 702
L+ ++ + + + + H Q R +Q + + +TE+ KQ
Sbjct: 418 QLRREQQLRREQ--EEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475
Query: 703 LNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTF-- 760
L + E L + ++ Q + Q Q ++++Q+L+ + +EE LQ
Sbjct: 476 LKRDQEEER--RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
Query: 761 PHPQSNNDQQREGSFFGQTKVEECFHGEN--QYSKSSEFETHNVQMGLEEVQNINRRNSP 818
Q +Q+ + + E+ E Q K + E + + EE + R
Sbjct: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
Query: 819 YSQTMKSSACKIQVSC-----SNNTHLVSENKEQTTHPELFAGNKTQNLHHMQYFPNNVI 873
+ ++ + +V L E E+ +L + + Q
Sbjct: 594 QEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQE 653
Query: 874 PKQDLLHRCFQEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQR---------YLIHNH 924
++ L R +E+E++ +Q + + R + ++ + A++R + + +
Sbjct: 654 RREQRLKR--EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESE 711
Query: 925 ANVF-------PVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQM 977
A+ P +G Q +K ++ + L+W ++ +QQ ++ Q Q
Sbjct: 712 ADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQW 771
Query: 978 HRPIKVEPG 986
K E G
Sbjct: 772 QAEEKSERG 780
Score = 33.1 bits (74), Expect = 1.6
Identities = 52/300 (17%), Positives = 114/300 (38%), Gaps = 36/300 (12%)
Query: 530 QQLMRNKEQEILKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAESHLKRNEASLPSI 589
QQL++ +E+E+ R++ + R + Y + ++ + + + E +R +
Sbjct: 903 QQLLQEEEEELQ--REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERER-- 958
Query: 590 LQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQ 649
QY+ + Q +Q G ++ Q K + E+ Q + Q ++
Sbjct: 959 -QYRKDKKLQQKEEQLLGEEP----------EKRRRQEREKKYREEEELQQEEEQLLREE 1007
Query: 650 HLQFQKPSHQVHFSKTDHLPKAHVQSLCGTR-----------FHFQQRADSQTEKLMSPV 698
+ ++ + + K D L + Q L R + ++ + E+L+
Sbjct: 1008 REKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEE 1067
Query: 699 L----KQHLNQQASETEPFSNSH--LLQHKPHKQAAQTQPSQSSHLPQNQQQQQKL---- 748
+Q L +Q + E LL+ +P K+ Q + Q + QQ++++L
Sbjct: 1068 RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127
Query: 749 QIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEECFHGENQYSKSSEFETHNVQMGLEE 808
+ K + + L+ + Q+ E + + E QY + E + Q+ EE
Sbjct: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187
Score = 32.7 bits (73), Expect = 2.1
Identities = 59/282 (20%), Positives = 111/282 (39%), Gaps = 33/282 (11%)
Query: 652 QFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETE 711
+ Q+ Q+ + + + + C QQ + + +Q L +Q E E
Sbjct: 1085 ELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEE 1144
Query: 712 PFSNSH--LLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQ 769
LL+ +P K+ Q Q + QQ++++L + +E+ Q Q
Sbjct: 1145 EVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEK------RRQERERQ 1198
Query: 770 QREGSFFGQTKVEECFHGENQYSKSS---EFETHNVQMGLEEVQNINRRNSPYSQTMKSS 826
RE + K ++ + E+Q S E E N +V R N + Q ++ S
Sbjct: 1199 YREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRD-NKVYCKGRENEQFRQ-LEDS 1256
Query: 827 ACKIQVSCSNNTHLVSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQ 886
+ + S + HL+ E +E+ ++ Q Q + P+++ L R Q++
Sbjct: 1257 QLRDRQSQQDLQHLLGEQQER---------DREQERRRWQQRDRH-FPEEEQLEREEQKE 1306
Query: 887 ----EQKSQQASVL----QGYKNRNQ--DMSGQQAAQLAQQR 918
++KSQ+ L + K R Q D ++ QL Q+R
Sbjct: 1307 AKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQER 1348
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.124 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,638,348
Number of Sequences: 37866
Number of extensions: 2601511
Number of successful extensions: 15423
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 325
Number of HSP's that attempted gapping in prelim test: 12141
Number of HSP's gapped (non-prelim): 2598
length of query: 1165
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1052
effective length of database: 13,968,660
effective search space: 14695030320
effective search space used: 14695030320
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.