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Search of human proteins with 221316769
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
(383 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens] 766 0.0
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens] 731 0.0
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens] 729 0.0
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens] 729 0.0
gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens] 721 0.0
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila... 655 0.0
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens] 588 e-168
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens] 582 e-166
gi|38201714 ELAV-like 1 [Homo sapiens] 487 e-138
gi|4506447 RNA binding motif, single stranded interacting protei... 116 4e-26
gi|8400718 RNA binding motif, single stranded interacting protei... 116 4e-26
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 115 7e-26
gi|51317355 RNA binding motif, single stranded interacting prote... 113 3e-25
gi|51317353 RNA binding motif, single stranded interacting prote... 113 3e-25
gi|51317351 RNA binding motif, single stranded interacting prote... 113 3e-25
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 107 1e-23
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 107 1e-23
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 107 1e-23
gi|4506449 RNA binding motif, single stranded interacting protei... 107 2e-23
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 107 2e-23
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 104 2e-22
gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 103 3e-22
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens] 100 4e-21
gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 99 6e-21
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 99 8e-21
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 93 5e-19
gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Hom... 91 2e-18
gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo... 91 2e-18
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 87 3e-17
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 87 3e-17
>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
Length = 383
Score = 766 bits (1979), Expect = 0.0
Identities = 383/383 (100%), Positives = 383/383 (100%)
Query: 1 MRLLLLREIVINESRNCSFMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDD 60
MRLLLLREIVINESRNCSFMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDD
Sbjct: 1 MRLLLLREIVINESRNCSFMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDD 60
Query: 61 SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 120
SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA
Sbjct: 61 SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 120
Query: 121 INTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRI 180
INTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRI
Sbjct: 121 INTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRI 180
Query: 181 LVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLS 240
LVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLS
Sbjct: 181 LVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLS 240
Query: 241 QLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGW 300
QLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGW
Sbjct: 241 QLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGW 300
Query: 301 CIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIAS 360
CIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIAS
Sbjct: 301 CIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIAS 360
Query: 361 LNGYRLGDRVLQVSFKTNKAHKS 383
LNGYRLGDRVLQVSFKTNKAHKS
Sbjct: 361 LNGYRLGDRVLQVSFKTNKAHKS 383
>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
Length = 366
Score = 731 bits (1886), Expect = 0.0
Identities = 364/364 (100%), Positives = 364/364 (100%)
Query: 20 MIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEF 79
MIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEF
Sbjct: 3 MIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEF 62
Query: 80 RSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYA 139
RSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYA
Sbjct: 63 RSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYA 122
Query: 140 RPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDK 199
RPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDK
Sbjct: 123 RPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDK 182
Query: 200 RIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQ 259
RIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQ
Sbjct: 183 RIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQ 242
Query: 260 RFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQL 319
RFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQL
Sbjct: 243 RFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQL 302
Query: 320 FGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 379
FGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK
Sbjct: 303 FGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 362
Query: 380 AHKS 383
AHKS
Sbjct: 363 AHKS 366
>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
Length = 369
Score = 729 bits (1881), Expect = 0.0
Identities = 363/363 (100%), Positives = 363/363 (100%)
Query: 21 IISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFR 80
IISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFR
Sbjct: 7 IISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFR 66
Query: 81 SLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR 140
SLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR
Sbjct: 67 SLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR 126
Query: 141 PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR 200
PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR
Sbjct: 127 PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR 186
Query: 201 IEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQR 260
IEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQR
Sbjct: 187 IEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQR 246
Query: 261 FRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLF 320
FRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLF
Sbjct: 247 FRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLF 306
Query: 321 GPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKA 380
GPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKA
Sbjct: 307 GPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKA 366
Query: 381 HKS 383
HKS
Sbjct: 367 HKS 369
>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
Length = 366
Score = 729 bits (1881), Expect = 0.0
Identities = 363/363 (100%), Positives = 363/363 (100%)
Query: 21 IISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFR 80
IISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFR
Sbjct: 4 IISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFR 63
Query: 81 SLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR 140
SLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR
Sbjct: 64 SLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR 123
Query: 141 PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR 200
PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR
Sbjct: 124 PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR 183
Query: 201 IEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQR 260
IEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQR
Sbjct: 184 IEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQR 243
Query: 261 FRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLF 320
FRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLF
Sbjct: 244 FRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLF 303
Query: 321 GPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKA 380
GPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKA
Sbjct: 304 GPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKA 363
Query: 381 HKS 383
HKS
Sbjct: 364 HKS 366
>gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
Length = 380
Score = 721 bits (1861), Expect = 0.0
Identities = 364/378 (96%), Positives = 364/378 (96%), Gaps = 14/378 (3%)
Query: 20 MIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEF 79
MIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEF
Sbjct: 3 MIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEF 62
Query: 80 RSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYA 139
RSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYA
Sbjct: 63 RSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYA 122
Query: 140 RPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDK 199
RPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDK
Sbjct: 123 RPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDK 182
Query: 200 RIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQ 259
RIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQ
Sbjct: 183 RIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQ 242
Query: 260 RFRLDNLLNMAYGVK--------------RFSPITIDGMTSLVGMNIPGHTGTGWCIFVY 305
RFRLDNLLNMAYGVK RFSPITIDGMTSLVGMNIPGHTGTGWCIFVY
Sbjct: 243 RFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVY 302
Query: 306 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 365
NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR
Sbjct: 303 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 362
Query: 366 LGDRVLQVSFKTNKAHKS 383
LGDRVLQVSFKTNKAHKS
Sbjct: 363 LGDRVLQVSFKTNKAHKS 380
>gi|115511032 ELAV (embryonic lethal, abnormal vision,
Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
Length = 359
Score = 655 bits (1689), Expect = 0.0
Identities = 324/360 (90%), Positives = 344/360 (95%), Gaps = 2/360 (0%)
Query: 25 MEPQVSNGPT-SNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLF 83
ME Q+SNGPT +NT+NGP++ N NC SP+ +G T+DSKTNLIVNYLPQNMTQEE +SLF
Sbjct: 1 METQLSNGPTCNNTANGPTTINNNCSSPVDSG-NTEDSKTNLIVNYLPQNMTQEELKSLF 59
Query: 84 GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS 143
GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS
Sbjct: 60 GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS 119
Query: 144 ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEA 203
ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTG+SRGVGFIRFDKRIEA
Sbjct: 120 ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEA 179
Query: 204 EEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRL 263
EEAIKGLNGQKP GATEPITVKFANNPSQK++QA+LSQLYQSPNRRYPGPL QAQRFRL
Sbjct: 180 EEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRL 239
Query: 264 DNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPF 323
DNLLNMAYGVKRFSP+TIDGMTSL G+NIPGH GTGWCIFVYNL+PD+DES+LWQ+FGPF
Sbjct: 240 DNLLNMAYGVKRFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPF 299
Query: 324 GAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS 383
GAV NVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK HK+
Sbjct: 300 GAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKA 359
>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
Length = 360
Score = 588 bits (1517), Expect = e-168
Identities = 299/365 (81%), Positives = 318/365 (87%), Gaps = 11/365 (3%)
Query: 21 IISTMEPQVSNGPTSNT-SNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEF 79
I+ ME QV GP NGP + T TDDSKTNLIVNYLPQNMTQ+EF
Sbjct: 5 ILGAMESQVGGGPAGPALPNGPL---------LGTNGATDDSKTNLIVNYLPQNMTQDEF 55
Query: 80 RSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYA 139
+SLFGSIG+IESCKLVRDKITGQSLGYGFVNY DP DA+KAINTLNGL+LQTKTIKVSYA
Sbjct: 56 KSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYA 115
Query: 140 RPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDK 199
RPSSASIRDANLYVSGLPKTM+QKE+EQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDK
Sbjct: 116 RPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDK 175
Query: 200 RIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQ 259
RIEAEEAIKGLNGQKP GA EPITVKFANNPSQK+ QALL+ LYQS RRY GPLHHQ Q
Sbjct: 176 RIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQ 235
Query: 260 RFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIP-GHTGTGWCIFVYNLSPDSDESVLWQ 318
RFRLDNLLNMAYGVKRFSPI IDGM+ L G+ + G G GWCIFVYNLSP++DESVLWQ
Sbjct: 236 RFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQ 295
Query: 319 LFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTN 378
LFGPFGAV NVKVIRDF TNKCKGFGFVTMTNYDEAAMAIASLNGYRLG+RVLQVSFKT+
Sbjct: 296 LFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTS 355
Query: 379 KAHKS 383
K HK+
Sbjct: 356 KQHKA 360
>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
Length = 367
Score = 582 bits (1499), Expect = e-166
Identities = 299/372 (80%), Positives = 318/372 (85%), Gaps = 18/372 (4%)
Query: 21 IISTMEPQVSNGPTSNT-SNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEF 79
I+ ME QV GP NGP + T TDDSKTNLIVNYLPQNMTQ+EF
Sbjct: 5 ILGAMESQVGGGPAGPALPNGPL---------LGTNGATDDSKTNLIVNYLPQNMTQDEF 55
Query: 80 RSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYA 139
+SLFGSIG+IESCKLVRDKITGQSLGYGFVNY DP DA+KAINTLNGL+LQTKTIKVSYA
Sbjct: 56 KSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYA 115
Query: 140 RPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDK 199
RPSSASIRDANLYVSGLPKTM+QKE+EQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDK
Sbjct: 116 RPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDK 175
Query: 200 RIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQ 259
RIEAEEAIKGLNGQKP GA EPITVKFANNPSQK+ QALL+ LYQS RRY GPLHHQ Q
Sbjct: 176 RIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQ 235
Query: 260 RFRLDNLLNMAYGVK-------RFSPITIDGMTSLVGMNIP-GHTGTGWCIFVYNLSPDS 311
RFRLDNLLNMAYGVK RFSPI IDGM+ L G+ + G G GWCIFVYNLSP++
Sbjct: 236 RFRLDNLLNMAYGVKSPLSLIARFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEA 295
Query: 312 DESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVL 371
DESVLWQLFGPFGAV NVKVIRDF TNKCKGFGFVTMTNYDEAAMAIASLNGYRLG+RVL
Sbjct: 296 DESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVL 355
Query: 372 QVSFKTNKAHKS 383
QVSFKT+K HK+
Sbjct: 356 QVSFKTSKQHKA 367
>gi|38201714 ELAV-like 1 [Homo sapiens]
Length = 326
Score = 487 bits (1253), Expect = e-138
Identities = 234/324 (72%), Positives = 273/324 (84%), Gaps = 13/324 (4%)
Query: 59 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 118
D +TNLIVNYLPQNMTQ+E RSLF SIGE+ES KL+RDK+ G SLGYGFVNY+ KDAE
Sbjct: 16 DIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAE 75
Query: 119 KAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITS 178
+AINTLNGLRLQ+KTIKVSYARPSS I+DANLY+SGLP+TMTQK++E +FS++GRII S
Sbjct: 76 RAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINS 135
Query: 179 RILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQAL 238
R+LVDQ TG+SRGV FIRFDKR EAEEAI NG KP G++EPITVKFA NP+Q + AL
Sbjct: 136 RVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVAL 195
Query: 239 LSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGT 298
LSQLY SP RR+ GP+HHQAQRF RFSP+ +D M+ L G+N+PG+ +
Sbjct: 196 LSQLYHSPARRFGGPVHHQAQRF-------------RFSPMGVDHMSGLSGVNVPGNASS 242
Query: 299 GWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAI 358
GWCIF+YNL D+DE +LWQ+FGPFGAV NVKVIRDFNTNKCKGFGFVTMTNY+EAAMAI
Sbjct: 243 GWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAI 302
Query: 359 ASLNGYRLGDRVLQVSFKTNKAHK 382
ASLNGYRLGD++LQVSFKTNK+HK
Sbjct: 303 ASLNGYRLGDKILQVSFKTNKSHK 326
Score = 59.3 bits (142), Expect = 6e-09
Identities = 54/193 (27%), Positives = 90/193 (46%), Gaps = 13/193 (6%)
Query: 139 ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFD 198
A I NL V+ LP+ MTQ EL LFS G + +++++ D+V G S G GF+ +
Sbjct: 10 AEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYV 69
Query: 199 KRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQ--KSSQALLSQLYQSPNRRYPGPLHH 256
+AE AI LNG + T I V +A S+ K + +S L ++ ++ +
Sbjct: 70 TAKDAERAINTLNGLRLQSKT--IKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFS 127
Query: 257 Q-----AQRFRLDNLLNMAYGVK--RFSPIT--IDGMTSLVGMNIPGHTGTGWCIFVYNL 307
+ R +D ++ GV RF + + +TS G PG + F N
Sbjct: 128 RFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANP 187
Query: 308 SPDSDESVLWQLF 320
+ + + ++L QL+
Sbjct: 188 NQNKNVALLSQLY 200
>gi|4506447 RNA binding motif, single stranded interacting protein 1
isoform c [Homo sapiens]
Length = 403
Score = 116 bits (290), Expect = 4e-26
Identities = 79/241 (32%), Positives = 120/241 (49%), Gaps = 32/241 (13%)
Query: 27 PQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSI 86
P P++ +SN SS++ N SKTNL + LP + T ++ L
Sbjct: 33 PMAPPSPSTTSSNNNSSSSSN-------SGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPY 85
Query: 87 GEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASI 146
G+I S K + DK T + GYGFV++ P A+KA++ L +Q + K P+
Sbjct: 86 GKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPT---- 141
Query: 147 RDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEA 206
NLY+S LP +M ++ELE + +G++I++RIL D +G SRGVGF R + + E
Sbjct: 142 ---NLYISNLPLSMDEQELENMLKPFGQVISTRILRDS-SGTSRGVGFARMESTEKCEAV 197
Query: 207 IKGLNG---QKPSGA---TEPITVKFANNPSQKSSQALLSQLYQSPNRRYPG--PLHHQA 258
I NG + P G TEP+ KFA+ +K Q+PN+ P P H +
Sbjct: 198 IGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKR---------QNPNKYIPNGRPWHREG 248
Query: 259 Q 259
+
Sbjct: 249 E 249
Score = 45.4 bits (106), Expect = 8e-05
Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 291 NIPGHTGTGWC------IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFG 344
N + +GW +++ L P + + L +L P+G + + K I D TNKCKG+G
Sbjct: 47 NSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYG 106
Query: 345 FVTMTNYDEAAMAIASL 361
FV + A A+++L
Sbjct: 107 FVDFDSPAAAQKAVSAL 123
Score = 37.0 bits (84), Expect = 0.030
Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
+++ NL DE L + PFG V + +++RD ++ +G GF M + ++ I
Sbjct: 143 LYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARMESTEKCEAVIGHF 201
Query: 362 NG 363
NG
Sbjct: 202 NG 203
>gi|8400718 RNA binding motif, single stranded interacting protein 1
isoform a [Homo sapiens]
Length = 406
Score = 116 bits (290), Expect = 4e-26
Identities = 79/241 (32%), Positives = 120/241 (49%), Gaps = 32/241 (13%)
Query: 27 PQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSI 86
P P++ +SN SS++ N SKTNL + LP + T ++ L
Sbjct: 33 PMAPPSPSTTSSNNNSSSSSN-------SGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPY 85
Query: 87 GEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASI 146
G+I S K + DK T + GYGFV++ P A+KA++ L +Q + K P+
Sbjct: 86 GKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPT---- 141
Query: 147 RDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEA 206
NLY+S LP +M ++ELE + +G++I++RIL D +G SRGVGF R + + E
Sbjct: 142 ---NLYISNLPLSMDEQELENMLKPFGQVISTRILRDS-SGTSRGVGFARMESTEKCEAV 197
Query: 207 IKGLNG---QKPSGA---TEPITVKFANNPSQKSSQALLSQLYQSPNRRYPG--PLHHQA 258
I NG + P G TEP+ KFA+ +K Q+PN+ P P H +
Sbjct: 198 IGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKR---------QNPNKYIPNGRPWHREG 248
Query: 259 Q 259
+
Sbjct: 249 E 249
Score = 45.4 bits (106), Expect = 8e-05
Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 291 NIPGHTGTGWC------IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFG 344
N + +GW +++ L P + + L +L P+G + + K I D TNKCKG+G
Sbjct: 47 NSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYG 106
Query: 345 FVTMTNYDEAAMAIASL 361
FV + A A+++L
Sbjct: 107 FVDFDSPAAAQKAVSAL 123
Score = 37.0 bits (84), Expect = 0.030
Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
+++ NL DE L + PFG V + +++RD ++ +G GF M + ++ I
Sbjct: 143 LYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARMESTEKCEAVIGHF 201
Query: 362 NG 363
NG
Sbjct: 202 NG 203
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 115 bits (288), Expect = 7e-26
Identities = 85/327 (25%), Positives = 153/327 (46%), Gaps = 60/327 (18%)
Query: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
N+ + L ++ + F + G I SCK+ D+ S G+GFV++ + A++AINT
Sbjct: 100 NIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQQAINT 157
Query: 124 LNGLRLQTKTIKVSY--------ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRI 175
+NG+ L + + V + A + ++ N+YV LP + ++ L+ LFSQ+G++
Sbjct: 158 MNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKM 217
Query: 176 ITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSS 235
++ +++ D +G SR GF+ F+K EA++A+ +NG++ SG
Sbjct: 218 LSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSG------------------ 258
Query: 236 QALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGH 295
Y G + +R N L +RF + D + G+N
Sbjct: 259 -----------RLLYAGRAQKRVER---QNELK-----RRFEQMKQDRLRRYQGVN---- 295
Query: 296 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 355
++V NL D+ L + F P+G + + KV+ + KGFGFV ++ +EA
Sbjct: 296 ------LYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEAT 347
Query: 356 MAIASLNGYRLGDRVLQVSFKTNKAHK 382
A+ +NG +G + L V+ K +
Sbjct: 348 KAVTEMNGRIVGTKPLYVALAQRKEER 374
Score = 82.4 bits (202), Expect = 6e-16
Identities = 46/151 (30%), Positives = 83/151 (54%), Gaps = 4/151 (2%)
Query: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
+L V L ++T+ F G I S ++ RD T +SLGY ++N+ P DAE+A++T
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
Query: 124 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 181
+N L+ + I++ +++ P N+++ L ++ K L FS +G I++ ++
Sbjct: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVA 131
Query: 182 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 212
D+ SRG GF+ F+ A++AI +NG
Sbjct: 132 CDE--HGSRGFGFVHFETHEAAQQAINTMNG 160
Score = 74.7 bits (182), Expect = 1e-13
Identities = 53/199 (26%), Positives = 99/199 (49%), Gaps = 25/199 (12%)
Query: 63 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 122
TN+ V LP ++ ++ + LF G++ S K++RD +G S +GFVN+ ++A+KA+
Sbjct: 191 TNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVV 249
Query: 123 TLNGLRLQTKTIKVSYA------------------RPSSASIRDANLYVSGLPKTMTQKE 164
+NG + + + A + + NLYV L ++ +
Sbjct: 250 HMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDK 309
Query: 165 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 224
L + FS YG I +++++ + G S+G GF+ F EA +A+ +NG+ T+P+ V
Sbjct: 310 LRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEATKAVTEMNGR--IVGTKPLYV 365
Query: 225 KFANNPSQKSSQALLSQLY 243
A ++ +A+L+ Y
Sbjct: 366 ALAQRKEER--KAILTNQY 382
Score = 46.2 bits (108), Expect = 5e-05
Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
IF+ NL D L+ F FG + + KV D + ++ GFGFV ++ A AI ++
Sbjct: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSR--GFGFVHFETHEAAQQAINTM 158
Query: 362 NGYRLGDRVLQVS-FKTNKAHKS 383
NG L DR + V FK+ + ++
Sbjct: 159 NGMLLNDRKVFVGHFKSRREREA 181
Score = 42.0 bits (97), Expect = 0.001
Identities = 19/70 (27%), Positives = 41/70 (58%), Gaps = 3/70 (4%)
Query: 296 TGTGW---CIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYD 352
+G+G+ ++V +L PD E++L++ F P G + +++V RD T + G+ ++
Sbjct: 4 SGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPA 63
Query: 353 EAAMAIASLN 362
+A A+ ++N
Sbjct: 64 DAERALDTMN 73
>gi|51317355 RNA binding motif, single stranded interacting protein
3 isoform 1 [Homo sapiens]
Length = 437
Score = 113 bits (283), Expect = 3e-25
Identities = 75/213 (35%), Positives = 110/213 (51%), Gaps = 23/213 (10%)
Query: 27 PQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSI 86
P P++N+S+ SSNN + SKTNL + LP T ++ L
Sbjct: 34 PMAPPSPSTNSSSNNSSNN---------SSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPY 84
Query: 87 GEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASI 146
G+I S K + DK T Q GYGFV++ P A+KA+ +L +Q + K P+
Sbjct: 85 GKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPT---- 140
Query: 147 RDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEA 206
NLY+S LP +M ++ELE + +G +I++RIL D GVSRGVGF R + + E
Sbjct: 141 ---NLYISNLPISMDEQELENMLKPFGHVISTRILRD-ANGVSRGVGFARMESTEKCEVV 196
Query: 207 IKGLNG---QKPSG---ATEPITVKFANNPSQK 233
I+ NG + P G +EP+ KFA+ +K
Sbjct: 197 IQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKK 229
Score = 48.1 bits (113), Expect = 1e-05
Identities = 23/60 (38%), Positives = 36/60 (60%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
+++ L P + + L +L P+G + + K I D NTN+CKG+GFV + A A+ASL
Sbjct: 63 LYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASL 122
Score = 37.4 bits (85), Expect = 0.023
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
+++ NL DE L + PFG V + +++RD N +G GF M + ++ + I
Sbjct: 142 LYISNLPISMDEQELENMLKPFGHVISTRILRDAN-GVSRGVGFARMESTEKCEVVIQHF 200
Query: 362 NG 363
NG
Sbjct: 201 NG 202
>gi|51317353 RNA binding motif, single stranded interacting protein
3 isoform 3 [Homo sapiens]
Length = 419
Score = 113 bits (283), Expect = 3e-25
Identities = 75/213 (35%), Positives = 110/213 (51%), Gaps = 23/213 (10%)
Query: 27 PQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSI 86
P P++N+S+ SSNN + SKTNL + LP T ++ L
Sbjct: 33 PMAPPSPSTNSSSNNSSNN---------SSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPY 83
Query: 87 GEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASI 146
G+I S K + DK T Q GYGFV++ P A+KA+ +L +Q + K P+
Sbjct: 84 GKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPT---- 139
Query: 147 RDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEA 206
NLY+S LP +M ++ELE + +G +I++RIL D GVSRGVGF R + + E
Sbjct: 140 ---NLYISNLPISMDEQELENMLKPFGHVISTRILRD-ANGVSRGVGFARMESTEKCEVV 195
Query: 207 IKGLNG---QKPSG---ATEPITVKFANNPSQK 233
I+ NG + P G +EP+ KFA+ +K
Sbjct: 196 IQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKK 228
Score = 48.1 bits (113), Expect = 1e-05
Identities = 23/60 (38%), Positives = 36/60 (60%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
+++ L P + + L +L P+G + + K I D NTN+CKG+GFV + A A+ASL
Sbjct: 62 LYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASL 121
Score = 37.4 bits (85), Expect = 0.023
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
+++ NL DE L + PFG V + +++RD N +G GF M + ++ + I
Sbjct: 141 LYISNLPISMDEQELENMLKPFGHVISTRILRDAN-GVSRGVGFARMESTEKCEVVIQHF 199
Query: 362 NG 363
NG
Sbjct: 200 NG 201
>gi|51317351 RNA binding motif, single stranded interacting protein
3 isoform 2 [Homo sapiens]
Length = 420
Score = 113 bits (283), Expect = 3e-25
Identities = 75/213 (35%), Positives = 110/213 (51%), Gaps = 23/213 (10%)
Query: 27 PQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSI 86
P P++N+S+ SSNN + SKTNL + LP T ++ L
Sbjct: 34 PMAPPSPSTNSSSNNSSNN---------SSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPY 84
Query: 87 GEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASI 146
G+I S K + DK T Q GYGFV++ P A+KA+ +L +Q + K P+
Sbjct: 85 GKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPT---- 140
Query: 147 RDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEA 206
NLY+S LP +M ++ELE + +G +I++RIL D GVSRGVGF R + + E
Sbjct: 141 ---NLYISNLPISMDEQELENMLKPFGHVISTRILRD-ANGVSRGVGFARMESTEKCEVV 196
Query: 207 IKGLNG---QKPSG---ATEPITVKFANNPSQK 233
I+ NG + P G +EP+ KFA+ +K
Sbjct: 197 IQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKK 229
Score = 48.1 bits (113), Expect = 1e-05
Identities = 23/60 (38%), Positives = 36/60 (60%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
+++ L P + + L +L P+G + + K I D NTN+CKG+GFV + A A+ASL
Sbjct: 63 LYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASL 122
Score = 37.4 bits (85), Expect = 0.023
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
+++ NL DE L + PFG V + +++RD N +G GF M + ++ + I
Sbjct: 142 LYISNLPISMDEQELENMLKPFGHVISTRILRDAN-GVSRGVGFARMESTEKCEVVIQHF 200
Query: 362 NG 363
NG
Sbjct: 201 NG 202
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 107 bits (268), Expect = 1e-23
Identities = 90/377 (23%), Positives = 163/377 (43%), Gaps = 72/377 (19%)
Query: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
+L V L ++T+ F G + S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 124 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 181
+N ++ K I++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 182 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ------------------------KPSG 217
D+ S+G F+ F+ + A++AI+ +NG K
Sbjct: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
Query: 218 ATEPITVKFANNPSQKSSQALLSQ--------LYQSPNRRYPG------PLHHQAQRF-- 261
T F +S + L SQ + + PN + G H A +
Sbjct: 190 FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVE 249
Query: 262 ---------------RLDNLLNMAYGVKR-FSPITIDGMTSLVGMNIPGHTGTGWCIFVY 305
R + +KR F + + ++ G+N+ ++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNL----------YIK 299
Query: 306 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 365
NL D+ L + F PFG++ + KV+ + KGFGFV ++ +EA A+ +NG
Sbjct: 300 NLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRI 357
Query: 366 LGDRVLQVSFKTNKAHK 382
+G + L V+ K +
Sbjct: 358 VGSKPLYVALAQRKEER 374
Score = 80.1 bits (196), Expect = 3e-15
Identities = 51/191 (26%), Positives = 94/191 (49%), Gaps = 23/191 (12%)
Query: 63 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 122
TN+ + + + E + LF G+ S K++RD G+S G+GFV+Y +DA KA+
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
Query: 123 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 164
+NG + K I V A+ + + NLY+ L T+ ++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
Query: 165 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 224
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ ++P+ V
Sbjct: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IVGSKPLYV 365
Query: 225 KFANNPSQKSS 235
A ++ +
Sbjct: 366 ALAQRKEERKA 376
Score = 46.2 bits (108), Expect = 5e-05
Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
+F+ NL D L+ F FG + + KV+ D N KG+ FV + A AI +
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
Query: 362 NGYRLGDRVLQVS-FKTNKAHKS 383
NG L DR + V FK+ K ++
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREA 181
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 107 bits (268), Expect = 1e-23
Identities = 90/377 (23%), Positives = 163/377 (43%), Gaps = 72/377 (19%)
Query: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
+L V L ++T+ F G + S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 124 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 181
+N ++ K I++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 182 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ------------------------KPSG 217
D+ S+G F+ F+ + A++AI+ +NG K
Sbjct: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
Query: 218 ATEPITVKFANNPSQKSSQALLSQ--------LYQSPNRRYPG------PLHHQAQRF-- 261
T F +S + L SQ + + PN + G H A +
Sbjct: 190 FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVE 249
Query: 262 ---------------RLDNLLNMAYGVKR-FSPITIDGMTSLVGMNIPGHTGTGWCIFVY 305
R + +KR F + + ++ G+N+ ++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNL----------YIK 299
Query: 306 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 365
NL D+ L + F PFG++ + KV+ + KGFGFV ++ +EA A+ +NG
Sbjct: 300 NLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRI 357
Query: 366 LGDRVLQVSFKTNKAHK 382
+G + L V+ K +
Sbjct: 358 VGSKPLYVALAQRKEER 374
Score = 80.1 bits (196), Expect = 3e-15
Identities = 51/191 (26%), Positives = 94/191 (49%), Gaps = 23/191 (12%)
Query: 63 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 122
TN+ + + + E + LF G+ S K++RD G+S G+GFV+Y +DA KA+
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
Query: 123 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 164
+NG + K I V A+ + + NLY+ L T+ ++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
Query: 165 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 224
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ ++P+ V
Sbjct: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IVGSKPLYV 365
Query: 225 KFANNPSQKSS 235
A ++ +
Sbjct: 366 ALAQRKEERKA 376
Score = 46.2 bits (108), Expect = 5e-05
Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
+F+ NL D L+ F FG + + KV+ D N KG+ FV + A AI +
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
Query: 362 NGYRLGDRVLQVS-FKTNKAHKS 383
NG L DR + V FK+ K ++
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREA 181
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 107 bits (268), Expect = 1e-23
Identities = 90/377 (23%), Positives = 163/377 (43%), Gaps = 72/377 (19%)
Query: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
+L V L ++T+ F G + S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 124 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 181
+N ++ K I++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 182 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ------------------------KPSG 217
D+ S+G F+ F+ + A++AI+ +NG K
Sbjct: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
Query: 218 ATEPITVKFANNPSQKSSQALLSQ--------LYQSPNRRYPG------PLHHQAQRF-- 261
T F +S + L SQ + + PN + G H A +
Sbjct: 190 FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVE 249
Query: 262 ---------------RLDNLLNMAYGVKR-FSPITIDGMTSLVGMNIPGHTGTGWCIFVY 305
R + +KR F + + ++ G+N+ ++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNL----------YIK 299
Query: 306 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 365
NL D+ L + F PFG++ + KV+ + KGFGFV ++ +EA A+ +NG
Sbjct: 300 NLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRI 357
Query: 366 LGDRVLQVSFKTNKAHK 382
+G + L V+ K +
Sbjct: 358 VGSKPLYVALAQRKEER 374
Score = 80.1 bits (196), Expect = 3e-15
Identities = 51/191 (26%), Positives = 94/191 (49%), Gaps = 23/191 (12%)
Query: 63 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 122
TN+ + + + E + LF G+ S K++RD G+S G+GFV+Y +DA KA+
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
Query: 123 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 164
+NG + K I V A+ + + NLY+ L T+ ++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
Query: 165 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 224
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ ++P+ V
Sbjct: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IVGSKPLYV 365
Query: 225 KFANNPSQKSS 235
A ++ +
Sbjct: 366 ALAQRKEERKA 376
Score = 46.2 bits (108), Expect = 5e-05
Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
+F+ NL D L+ F FG + + KV+ D N KG+ FV + A AI +
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
Query: 362 NGYRLGDRVLQVS-FKTNKAHKS 383
NG L DR + V FK+ K ++
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREA 181
>gi|4506449 RNA binding motif, single stranded interacting protein 2
[Homo sapiens]
Length = 407
Score = 107 bits (267), Expect = 2e-23
Identities = 74/235 (31%), Positives = 115/235 (48%), Gaps = 25/235 (10%)
Query: 14 SRNCSFMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQN 73
+RN +S + P+++T N S +N N SKTNL + L
Sbjct: 17 NRNNKKPYVSLAQQMAPPSPSNSTPNSSSGSNGN----------DQLSKTNLYIRGLQPG 66
Query: 74 MTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKT 133
T ++ L G+I S K + DK T + GYGFV++ P A+KA+ L +Q +
Sbjct: 67 TTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQM 126
Query: 134 IKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVG 193
K P+ NLY+S LP +M ++ELE + +G++I++RIL D +G SRGVG
Sbjct: 127 AKQQEQDPT-------NLYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGTSRGVG 178
Query: 194 FIRFDKRIEAEEAIKGLNG---QKPSGA---TEPITVKFAN-NPSQKSSQALLSQ 241
F R + + E I NG + P G ++P+ KFA+ P ++ +Q Q
Sbjct: 179 FARMESTEKCEAIITHFNGKYIKTPPGVPAPSDPLLCKFADGGPKKRQNQGKFVQ 233
Score = 45.8 bits (107), Expect = 6e-05
Identities = 21/60 (35%), Positives = 34/60 (56%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
+++ L P + + L +L P+G + + K I D TNKCKG+GFV + A A+ +L
Sbjct: 58 LYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTAL 117
Score = 35.4 bits (80), Expect = 0.087
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
+++ NL DE L + PFG V + +++RD + +G GF M + ++ I
Sbjct: 137 LYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGTSRGVGFARMESTEKCEAIITHF 195
Query: 362 NG 363
NG
Sbjct: 196 NG 197
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 107 bits (266), Expect = 2e-23
Identities = 81/329 (24%), Positives = 152/329 (46%), Gaps = 64/329 (19%)
Query: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
N+ + L +++ + F + G I SCK+V D+ S GYGFV++ + AE+AI
Sbjct: 100 NIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEK 157
Query: 124 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 173
+NG+ L + KV R S R+A N+Y+ + M + L+ LF ++G
Sbjct: 158 MNGMLLNDR--KVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFG 215
Query: 174 RIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQK 233
++ +++ D+ +G S+G GF+ F++ +A++A+ +NG++ +G + I V A ++
Sbjct: 216 PALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNG--KQIYVGRAQKKVER 272
Query: 234 SSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIP 293
++ ++F + D +T G+N
Sbjct: 273 QTEL-----------------------------------KRKFEQMKQDRITRYQGVN-- 295
Query: 294 GHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDE 353
++V NL D+ L + F PFG + + KV+ + + KGFGFV ++ +E
Sbjct: 296 --------LYVKNLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEE 345
Query: 354 AAMAIASLNGYRLGDRVLQVSFKTNKAHK 382
A A+ +NG + + L V+ K +
Sbjct: 346 ATKAVTEMNGRIVATKPLYVALAQRKEER 374
Score = 89.7 bits (221), Expect = 4e-18
Identities = 49/151 (32%), Positives = 88/151 (58%), Gaps = 4/151 (2%)
Query: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
+L V L ++T+ F G I S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 124 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 181
+N ++ K +++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 182 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 212
D+ S+G GF+ F+ + AE AI+ +NG
Sbjct: 132 CDE--NGSKGYGFVHFETQEAAERAIEKMNG 160
Score = 83.2 bits (204), Expect = 4e-16
Identities = 61/213 (28%), Positives = 105/213 (49%), Gaps = 28/213 (13%)
Query: 63 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 122
TN+ + ++M E + LFG G S K++ D+ +G+S G+GFV++ +DA+KA++
Sbjct: 191 TNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVD 249
Query: 123 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 164
+NG L K I V A+ + NLYV L + +
Sbjct: 250 EMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDER 309
Query: 165 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 224
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ AT+P+ V
Sbjct: 310 LRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGR--IVATKPLYV 365
Query: 225 KFANNPSQKSSQALLSQLY---QSPNRRYPGPL 254
A ++ QA L+ Y + R P P+
Sbjct: 366 ALAQRKEER--QAHLTNQYMQRMASVRAVPNPV 396
Score = 49.3 bits (116), Expect = 6e-06
Identities = 30/83 (36%), Positives = 42/83 (50%), Gaps = 3/83 (3%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
IF+ NL D L+ F FG + + KV+ D N KG+GFV + A AI +
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYGFVHFETQEAAERAIEKM 158
Query: 362 NGYRLGDRVLQVS-FKTNKAHKS 383
NG L DR + V FK+ K ++
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREA 181
Score = 45.4 bits (106), Expect = 8e-05
Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Query: 141 PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR 200
PS+ S A+LYV L +T+ L + FS G I++ R+ D +T S G ++ F +
Sbjct: 3 PSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQP 62
Query: 201 IEAEEAIKGLNGQKPSGATEPITVKFA-NNPSQKSS 235
+AE A+ +N G +P+ + ++ +PS + S
Sbjct: 63 ADAERALDTMNFDVIKG--KPVRIMWSQRDPSLRKS 96
Score = 42.0 bits (97), Expect = 0.001
Identities = 18/61 (29%), Positives = 36/61 (59%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
++V +L PD E++L++ F P G + +++V RD T + G+ +V +A A+ ++
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 362 N 362
N
Sbjct: 73 N 73
>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
Length = 375
Score = 104 bits (259), Expect = 2e-22
Identities = 74/318 (23%), Positives = 144/318 (45%), Gaps = 55/318 (17%)
Query: 59 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 118
D L V L +++T+ LF IG +SCK++ + + Y FV + + +DA
Sbjct: 5 DGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAA 62
Query: 119 KAINTLNGLRLQTKTIKVSYARPSSASIRDA----NLYVSGLPKTMTQKELEQLFSQYGR 174
A+ +NG ++ K +KV++A S+ +D +++V L +T ++++ F+ +G+
Sbjct: 63 AALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGK 122
Query: 175 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKS 234
I +R++ D TG S+G GF+ F +++AE AI + GQ G P+ KS
Sbjct: 123 ISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKS 182
Query: 235 SQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPG 294
+Q + ++ R ++++N + SP
Sbjct: 183 TQ------------------ENNTKQLRFEDVVNQS------SP---------------- 202
Query: 295 HTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEA 354
++ ++ + ++ Q F PFG + ++V + KG+ FV + ++ A
Sbjct: 203 ---KNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESA 253
Query: 355 AMAIASLNGYRLGDRVLQ 372
A AI S+NG + V++
Sbjct: 254 AHAIVSVNGTTIEGHVVK 271
Score = 59.3 bits (142), Expect = 6e-09
Identities = 29/84 (34%), Positives = 48/84 (57%)
Query: 296 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 355
T + +FV +LSP+ + F PFG +++ +V++D T K KG+GFV+ N +A
Sbjct: 93 TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAE 152
Query: 356 MAIASLNGYRLGDRVLQVSFKTNK 379
AI + G LG R ++ ++ T K
Sbjct: 153 NAIVHMGGQWLGGRQIRTNWATRK 176
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/76 (30%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
++V NLS D E ++ QLF G + K+I + +N + FV + +AA A+A++
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSN--DPYCFVEFYEHRDAAAALAAM 68
Query: 362 NGYRLGDRVLQVSFKT 377
NG ++ + ++V++ T
Sbjct: 69 NGRKILGKEVKVNWAT 84
Score = 31.2 bits (69), Expect = 1.6
Identities = 17/73 (23%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 70 LPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL 129
+ +T + R F G+I ++ +K GY FV + + A AI ++NG +
Sbjct: 212 IASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVSVNGTTI 265
Query: 130 QTKTIKVSYARPS 142
+ +K + + S
Sbjct: 266 EGHVVKCYWGKES 278
>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
Length = 375
Score = 103 bits (256), Expect = 3e-22
Identities = 78/318 (24%), Positives = 145/318 (45%), Gaps = 55/318 (17%)
Query: 59 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 118
D+ L V L +++T+ LF IG ++CK++ D T + Y FV + + + A
Sbjct: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
Query: 119 KAINTLNGLRLQTKTIKVSYARPSSASIRDA----NLYVSGLPKTMTQKELEQLFSQYGR 174
A+ +NG ++ K +KV++A S+ +D +++V L +T ++++ F+ +GR
Sbjct: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGR 120
Query: 175 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKS 234
I +R++ D TG S+G GF+ F + +AE AI+ + GQ G P+ KS
Sbjct: 121 ISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKS 180
Query: 235 SQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPG 294
+ Y+S ++ D ++N + SP
Sbjct: 181 T-------YES-----------NTKQLSYDEVVNQS------SP---------------- 200
Query: 295 HTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEA 354
+ ++ ++ E ++ Q F PFG + ++V D KG+ FV +++ A
Sbjct: 201 ---SNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESA 251
Query: 355 AMAIASLNGYRLGDRVLQ 372
A AI S+NG + V++
Sbjct: 252 AHAIVSVNGTTIEGHVVK 269
Score = 58.9 bits (141), Expect = 7e-09
Identities = 29/84 (34%), Positives = 48/84 (57%)
Query: 296 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 355
T + +FV +LSP+ + F PFG +++ +V++D T K KG+GFV+ N +A
Sbjct: 91 TSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAE 150
Query: 356 MAIASLNGYRLGDRVLQVSFKTNK 379
AI + G LG R ++ ++ T K
Sbjct: 151 NAIQQMGGQWLGGRQIRTNWATRK 174
Score = 42.7 bits (99), Expect = 5e-04
Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
++V NLS D E+++ QLF G N K+I D N + FV + AA A+A++
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGN--DPYCFVEFHEHRHAAAALAAM 66
Query: 362 NGYRLGDRVLQVSFKT 377
NG ++ + ++V++ T
Sbjct: 67 NGRKIMGKEVKVNWAT 82
Score = 32.0 bits (71), Expect = 0.96
Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Query: 74 MTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKT 133
+T++ R F G+I ++ DK GY FV + + A AI ++NG ++
Sbjct: 214 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 267
Query: 134 IKVSYAR 140
+K + +
Sbjct: 268 VKCYWGK 274
>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
Length = 392
Score = 99.8 bits (247), Expect = 4e-21
Identities = 76/333 (22%), Positives = 147/333 (44%), Gaps = 68/333 (20%)
Query: 59 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRD----KITGQSLG--------- 105
D L V L +++T+ LF IG +SCK++ + + S+G
Sbjct: 5 DGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSN 64
Query: 106 --YGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDA----NLYVSGLPKT 159
Y FV + + +DA A+ +NG ++ K +KV++A S+ +D +++V L
Sbjct: 65 DPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPE 124
Query: 160 MTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGAT 219
+T ++++ F+ +G+I +R++ D TG S+G GF+ F +++AE AI + GQ G
Sbjct: 125 ITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQ 184
Query: 220 EPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPI 279
P+ KS+Q + ++ R ++++N + SP
Sbjct: 185 IRTNWATRKPPAPKSTQ------------------ENNTKQLRFEDVVNQS------SP- 219
Query: 280 TIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNK 339
++ ++ + ++ Q F PFG + ++V +
Sbjct: 220 ------------------KNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----- 256
Query: 340 CKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQ 372
KG+ FV + ++ AA AI S+NG + V++
Sbjct: 257 -KGYSFVRFSTHESAAHAIVSVNGTTIEGHVVK 288
Score = 59.3 bits (142), Expect = 6e-09
Identities = 29/84 (34%), Positives = 48/84 (57%)
Query: 296 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 355
T + +FV +LSP+ + F PFG +++ +V++D T K KG+GFV+ N +A
Sbjct: 110 TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAE 169
Query: 356 MAIASLNGYRLGDRVLQVSFKTNK 379
AI + G LG R ++ ++ T K
Sbjct: 170 NAIVHMGGQWLGGRQIRTNWATRK 193
Score = 35.0 bits (79), Expect = 0.11
Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 15/91 (16%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRD----FNTNKCKGFG-----------FV 346
++V NLS D E ++ QLF G + K+I + N GF FV
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70
Query: 347 TMTNYDEAAMAIASLNGYRLGDRVLQVSFKT 377
+ +AA A+A++NG ++ + ++V++ T
Sbjct: 71 EFYEHRDAAAALAAMNGRKILGKEVKVNWAT 101
Score = 31.2 bits (69), Expect = 1.6
Identities = 17/73 (23%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 70 LPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL 129
+ +T + R F G+I ++ +K GY FV + + A AI ++NG +
Sbjct: 229 IASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVSVNGTTI 282
Query: 130 QTKTIKVSYARPS 142
+ +K + + S
Sbjct: 283 EGHVVKCYWGKES 295
>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
Length = 386
Score = 99.0 bits (245), Expect = 6e-21
Identities = 78/329 (23%), Positives = 145/329 (44%), Gaps = 66/329 (20%)
Query: 59 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 118
D+ L V L +++T+ LF IG ++CK++ D T + Y FV + + + A
Sbjct: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
Query: 119 KAINTLNGLRLQTKTIKVSYARPSSASIRDA---------------NLYVSGLPKTMTQK 163
A+ +NG ++ K +KV++A S+ +D +++V L +T +
Sbjct: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE 120
Query: 164 ELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPIT 223
+++ F+ +GRI +R++ D TG S+G GF+ F + +AE AI+ + GQ G
Sbjct: 121 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN 180
Query: 224 VKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDG 283
P+ KS+ Y+S ++ D ++N + SP
Sbjct: 181 WATRKPPAPKST-------YES-----------NTKQLSYDEVVNQS------SP----- 211
Query: 284 MTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGF 343
+ ++ ++ E ++ Q F PFG + ++V D KG+
Sbjct: 212 --------------SNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGY 251
Query: 344 GFVTMTNYDEAAMAIASLNGYRLGDRVLQ 372
FV +++ AA AI S+NG + V++
Sbjct: 252 SFVRFNSHESAAHAIVSVNGTTIEGHVVK 280
Score = 82.8 bits (203), Expect = 5e-16
Identities = 54/204 (26%), Positives = 92/204 (45%), Gaps = 28/204 (13%)
Query: 36 NTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLV 95
N + PSS ++ S ++ V L +T E+ ++ F G I ++V
Sbjct: 79 NWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVV 138
Query: 96 RDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR---PSSASIRDAN-- 150
+D TG+S GYGFV++ + DAE AI + G L + I+ ++A P+ S ++N
Sbjct: 139 KDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTK 198
Query: 151 -----------------LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVG 193
+Y G+ +T++ + Q FS +G+I+ R+ D +G
Sbjct: 199 QLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYS 252
Query: 194 FIRFDKRIEAEEAIKGLNGQKPSG 217
F+RF+ A AI +NG G
Sbjct: 253 FVRFNSHESAAHAIVSVNGTTIEG 276
Score = 68.9 bits (167), Expect = 7e-12
Identities = 56/229 (24%), Positives = 95/229 (41%), Gaps = 52/229 (22%)
Query: 151 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 210
LYV L + +T+ + QLFSQ G ++++D T + F+ F + A A+ +
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66
Query: 211 NGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMA 270
NG+K G + + V +A PS + S + + +R H
Sbjct: 67 NGRKIMG--KEVKVNWATTPSSQKKDTSSSTVVST--QRSQDHFH--------------- 107
Query: 271 YGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVK 330
+FV +LSP+ + F PFG +++ +
Sbjct: 108 -------------------------------VFVGDLSPEITTEDIKAAFAPFGRISDAR 136
Query: 331 VIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 379
V++D T K KG+GFV+ N +A AI + G LG R ++ ++ T K
Sbjct: 137 VVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185
Score = 32.0 bits (71), Expect = 0.96
Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Query: 74 MTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKT 133
+T++ R F G+I ++ DK GY FV + + A AI ++NG ++
Sbjct: 225 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 278
Query: 134 IKVSYAR 140
+K + +
Sbjct: 279 VKCYWGK 285
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 98.6 bits (244), Expect = 8e-21
Identities = 77/327 (23%), Positives = 147/327 (44%), Gaps = 60/327 (18%)
Query: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
N+ V L +++ + + G I SC +V D+ S GYGFV++ + AE+AI
Sbjct: 100 NIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDE--NGSKGYGFVHFETHEAAERAIKK 157
Query: 124 LNGLRL--------QTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRI 175
+NG+ L Q K+ K A + + N+Y+ + M + L+ LF ++G
Sbjct: 158 MNGMLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPA 217
Query: 176 ITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSS 235
++ +++ D+ +G S+G GF+ F++ +A++A+ +NG++ +G + I V A ++ +
Sbjct: 218 LSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNG--KQIYVGRAQKKVERQT 274
Query: 236 QALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGH 295
+ R + + R+++ NL
Sbjct: 275 EL---------KRTFEQMKQDRITRYQVVNL----------------------------- 296
Query: 296 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 355
+V NL D+ L + F PFG + + KV+ + + KGFGFV ++ +EA
Sbjct: 297 -------YVKNLDDGIDDERLRKAFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEAT 347
Query: 356 MAIASLNGYRLGDRVLQVSFKTNKAHK 382
A+ +NG + + L V+ K +
Sbjct: 348 KAVTEMNGRIVATKPLYVALAQRKEER 374
Score = 83.2 bits (204), Expect = 4e-16
Identities = 61/214 (28%), Positives = 104/214 (48%), Gaps = 33/214 (15%)
Query: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
N+ + ++M E + LFG G S K++ D+ +G+S G+GFV++ +DA+KA++
Sbjct: 192 NVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDE 250
Query: 124 LNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKEL 165
+NG L K I V A+ + NLYV L + + L
Sbjct: 251 MNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERL 310
Query: 166 EQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVK 225
+ FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ AT+P+ V
Sbjct: 311 RKAFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGR--IVATKPLYVA 366
Query: 226 FANNPSQKSSQALLSQLYQS--------PNRRYP 251
A ++ QA L+ Y PN+R P
Sbjct: 367 LAQRKEER--QAYLTNEYMQRMASVRAVPNQRAP 398
Score = 81.6 bits (200), Expect = 1e-15
Identities = 49/156 (31%), Positives = 83/156 (53%), Gaps = 4/156 (2%)
Query: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
+L V L ++T+ F G I S ++ RD IT S Y +VN+ KDAE A++T
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDT 71
Query: 124 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 181
+N ++ K +++ +++ PS N++V L K++ K L S +G I++ ++
Sbjct: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVV 131
Query: 182 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSG 217
D+ S+G GF+ F+ AE AIK +NG +G
Sbjct: 132 CDE--NGSKGYGFVHFETHEAAERAIKKMNGMLLNG 165
Score = 72.4 bits (176), Expect = 6e-13
Identities = 68/276 (24%), Positives = 116/276 (42%), Gaps = 40/276 (14%)
Query: 141 PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR 200
PS+ S A+LYV L +T+ L + FS G I++ RI D +T S ++ F
Sbjct: 3 PSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHT 62
Query: 201 IEAEEAIKGLNGQKPSGATEPITVKFA-NNPSQKSS---QALLSQLYQSPNRRYPGPLHH 256
+AE A+ +N G +P+ + ++ +PS + S + L +S N + L+
Sbjct: 63 KDAEHALDTMNFDVIKG--KPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNK---ALYD 117
Query: 257 QAQRFR--------LDNLLNMAYG-------------VKRFSPITIDGMTSLVGM----- 290
F D + YG +K+ + + ++G VG
Sbjct: 118 TVSAFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRK 177
Query: 291 ----NIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFV 346
+ +++ N D D+ L LFG FG +VKV+ D + K KGFGFV
Sbjct: 178 EREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD-ESGKSKGFGFV 236
Query: 347 TMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHK 382
+ +++A A+ +NG L + + V K +
Sbjct: 237 SFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVER 272
Score = 42.0 bits (97), Expect = 0.001
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
IFV NL + L+ FG + + V+ D N +K G+GFV ++ A AI +
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGSK--GYGFVHFETHEAAERAIKKM 158
Query: 362 NGYRL-GDRVLQVSFKTNKAHKS 383
NG L G +V FK+ K ++
Sbjct: 159 NGMLLNGRKVFVGQFKSRKEREA 181
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 92.8 bits (229), Expect = 5e-19
Identities = 79/322 (24%), Positives = 147/322 (45%), Gaps = 66/322 (20%)
Query: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
N+ + L +++ + F + G+I S K++ D S GY FV++ + A++AI
Sbjct: 99 NVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDD--QGSKGYAFVHFQNQSAADRAIEE 156
Query: 124 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 173
+NG L K KV R + R+A N+Y+ M + L+ +FS+YG
Sbjct: 157 MNGKLL--KGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYG 214
Query: 174 RIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQK 233
+ ++ +++ D +G S+G GF+ FD A++A++ +NG+ +G + F +K
Sbjct: 215 KTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEMNGRDING-----QLIFVGRAQKK 268
Query: 234 -SSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNI 292
QA L Q+++ Q +R R+ GVK
Sbjct: 269 VERQAELKQMFE------------QLKRERIRG----CQGVK------------------ 294
Query: 293 PGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYD 352
+++ NL D+ L F FG+++ VKV+++ + KGFG + ++ +
Sbjct: 295 ---------LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQE--EGQSKGFGLICFSSPE 343
Query: 353 EAAMAIASLNGYRLGDRVLQVS 374
+A A+ +NG LG + L ++
Sbjct: 344 DATKAMTEMNGRILGSKPLSIA 365
Score = 87.8 bits (216), Expect = 1e-17
Identities = 46/156 (29%), Positives = 95/156 (60%), Gaps = 4/156 (2%)
Query: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
+L V L ++T++ F ++G + S ++ RD++T +SLGY +VN++ DA+KA++T
Sbjct: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
Query: 124 LNGLRLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 181
+N ++ K+I++ +++ + R N+++ L K++ K L + FS +G+I++S+++
Sbjct: 71 MNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVM 130
Query: 182 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSG 217
D S+G F+ F + A+ AI+ +NG+ G
Sbjct: 131 SDDQG--SKGYAFVHFQNQSAADRAIEEMNGKLLKG 164
Score = 66.2 bits (160), Expect = 5e-11
Identities = 47/169 (27%), Positives = 79/169 (46%), Gaps = 21/169 (12%)
Query: 63 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 122
TN+ + +M E + +F G+ S K++ D +G+S G+GFV++ + A+KA+
Sbjct: 190 TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVE 248
Query: 123 TLNGLRLQTKTIKVSYA------------------RPSSASIRDANLYVSGLPKTMTQKE 164
+NG + + I V A R + LY+ L T+ ++
Sbjct: 249 EMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEK 308
Query: 165 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ 213
L FS +G I SR+ V Q G S+G G I F +A +A+ +NG+
Sbjct: 309 LRNEFSSFGSI--SRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGR 355
Score = 48.1 bits (113), Expect = 1e-05
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 65 LIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 124
L + L + E+ R+ F S G I K+++++ GQS G+G + + P+DA KA+ +
Sbjct: 295 LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEE--GQSKGFGLICFSSPEDATKAMTEM 352
Query: 125 NGLRLQTKTIKVSYAR 140
NG L +K + ++ A+
Sbjct: 353 NGRILGSKPLSIALAQ 368
Score = 47.0 bits (110), Expect = 3e-05
Identities = 23/81 (28%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
+++ N D D+ L +F +G +VKV+ D ++ K KGFGFV+ +++ A A+ +
Sbjct: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEM 250
Query: 362 NGYRLGDRVLQVSFKTNKAHK 382
NG + +++ V K +
Sbjct: 251 NGRDINGQLIFVGRAQKKVER 271
Score = 42.4 bits (98), Expect = 7e-04
Identities = 24/69 (34%), Positives = 40/69 (57%)
Query: 143 SASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIE 202
+A R A+LYV L +T+ L + FS G +++ RI DQVT S G ++ F + +
Sbjct: 4 AAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLAD 63
Query: 203 AEEAIKGLN 211
A++A+ +N
Sbjct: 64 AQKALDTMN 72
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
+F+ NL D L++ F FG + + KV+ D KG+ FV N A AI +
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD--DQGSKGYAFVHFQNQSAADRAIEEM 157
Query: 362 NGYRL-GDRVLQVSFKTNK 379
NG L G +V FK K
Sbjct: 158 NGKLLKGCKVFVGRFKNRK 176
>gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Homo
sapiens]
Length = 200
Score = 90.5 bits (223), Expect = 2e-18
Identities = 51/151 (33%), Positives = 85/151 (56%), Gaps = 4/151 (2%)
Query: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
+L V L +T+ F G I S ++ RDKIT +SLGY +VNY P DA++A+ T
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 124 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 181
LN ++ + +++ +++ PS N+++ L KT+ K L +FS +G I++ ++
Sbjct: 63 LNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVA 122
Query: 182 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 212
D+ +G GF+ F K+ AE AI +NG
Sbjct: 123 CDEKG--PKGYGFVHFQKQESAERAIDVMNG 151
Score = 43.1 bits (100), Expect = 4e-04
Identities = 23/73 (31%), Positives = 42/73 (57%), Gaps = 2/73 (2%)
Query: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
N+ + L + + + ++F + G I SCK+ D+ + GYGFV++ + AE+AI+
Sbjct: 91 NVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEKGPK--GYGFVHFQKQESAERAIDV 148
Query: 124 LNGLRLQTKTIKV 136
+NG+ L + I V
Sbjct: 149 MNGMFLNYRKIFV 161
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
+F+ NL D L+ +F FG + + KV D KG+GFV + A AI +
Sbjct: 92 VFIKNLGKTIDNKALYNIFSAFGNILSCKVACD--EKGPKGYGFVHFQKQESAERAIDVM 149
Query: 362 NGYRLGDRVLQVS-FKTNKAHKS 383
NG L R + V FK++K ++
Sbjct: 150 NGMFLNYRKIFVGRFKSHKEREA 172
>gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo
sapiens]
Length = 200
Score = 90.5 bits (223), Expect = 2e-18
Identities = 51/151 (33%), Positives = 85/151 (56%), Gaps = 4/151 (2%)
Query: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
+L V L +T+ F G I S ++ RDKIT +SLGY +VNY P DA++A+ T
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 124 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 181
LN ++ + +++ +++ PS N+++ L KT+ K L +FS +G I++ ++
Sbjct: 63 LNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVA 122
Query: 182 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 212
D+ +G GF+ F K+ AE AI +NG
Sbjct: 123 CDEKG--PKGYGFVHFQKQESAERAIDVMNG 151
Score = 43.1 bits (100), Expect = 4e-04
Identities = 23/73 (31%), Positives = 42/73 (57%), Gaps = 2/73 (2%)
Query: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
N+ + L + + + ++F + G I SCK+ D+ + GYGFV++ + AE+AI+
Sbjct: 91 NVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEKGPK--GYGFVHFQKQESAERAIDV 148
Query: 124 LNGLRLQTKTIKV 136
+NG+ L + I V
Sbjct: 149 MNGMFLNYRKIFV 161
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
+F+ NL D L+ +F FG + + KV D KG+GFV + A AI +
Sbjct: 92 VFIKNLGKTIDNKALYNIFSAFGNILSCKVACD--EKGPKGYGFVHFQKQESAERAIDVM 149
Query: 362 NGYRLGDRVLQVS-FKTNKAHKS 383
NG L R + V FK++K ++
Sbjct: 150 NGMFLNYRKIFVGRFKSHKEREA 172
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 87.0 bits (214), Expect = 3e-17
Identities = 76/320 (23%), Positives = 142/320 (44%), Gaps = 61/320 (19%)
Query: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
N+ + L +++ LF + G I SCK+V D S GY +V++ A +AI
Sbjct: 107 NIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRAIWH 164
Query: 124 LNGLRLQTKTIKVS---YARPSSASIRD------ANLYVSGLPKTMTQKELEQLFSQYGR 174
+NG+RL + + V + +A +R N++V + + ++L++LF +YG
Sbjct: 165 MNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGP 224
Query: 175 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKS 234
+ +++ D +G S+G GF+R++ A++A+ L+G+ G + +QK
Sbjct: 225 TESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYV------GRAQKK 277
Query: 235 SQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPG 294
+ L L + +R RL K P
Sbjct: 278 IERL-------------AELRRRFERLRLKE--------KSRPP---------------- 300
Query: 295 HTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEA 354
G I++ NL ++ L + F FG+++ KV+ + + KGFG V ++++EA
Sbjct: 301 ----GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEA 354
Query: 355 AMAIASLNGYRLGDRVLQVS 374
A+ +NG +G + L V+
Sbjct: 355 TKAVDEMNGRIVGSKPLHVT 374
Score = 81.3 bits (199), Expect = 1e-15
Identities = 47/164 (28%), Positives = 82/164 (50%), Gaps = 4/164 (2%)
Query: 51 PMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVN 110
P G K L V L ++T++ F G + ++ RD +T LGYG+VN
Sbjct: 6 PNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVN 65
Query: 111 YIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMTQKELEQL 168
+ P DAE A+NT+N + K ++ +++P + N+++ L K++ + L L
Sbjct: 66 FRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYL 125
Query: 169 FSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 212
FS +G I++ +++ D S+G ++ FD A AI +NG
Sbjct: 126 FSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRAIWHMNG 167
Score = 71.6 bits (174), Expect = 1e-12
Identities = 44/169 (26%), Positives = 85/169 (50%), Gaps = 21/169 (12%)
Query: 63 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 122
TN+ V + ++ E+ + LF G ES K++RD +G+S G+GFV Y + A+KA+
Sbjct: 199 TNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRYETHEAAQKAVL 257
Query: 123 TLNGLRLQTKTIKVSYARPSSASIRDAN------------------LYVSGLPKTMTQKE 164
L+G + K + V A+ + + +Y+ L +T+ ++
Sbjct: 258 DLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEK 317
Query: 165 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ 213
L++ FS +G I ++++++ G +G G + F EA +A+ +NG+
Sbjct: 318 LKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEATKAVDEMNGR 364
Score = 53.9 bits (128), Expect = 2e-07
Identities = 30/81 (37%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
+FV N+ D D+ L +LF +G +VKVIRD + K KGFGFV ++ A A+ L
Sbjct: 201 VFVKNIGDDIDDEKLKELFCEYGPTESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDL 259
Query: 362 NGYRLGDRVLQVSFKTNKAHK 382
+G + +VL V K +
Sbjct: 260 HGKSIDGKVLYVGRAQKKIER 280
Score = 36.2 bits (82), Expect = 0.051
Identities = 18/61 (29%), Positives = 33/61 (54%)
Query: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
++V +L PD E +L++ F P G + ++ RD T G+G+V +A A+ ++
Sbjct: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
Query: 362 N 362
N
Sbjct: 80 N 80
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 86.7 bits (213), Expect = 3e-17
Identities = 54/172 (31%), Positives = 92/172 (53%), Gaps = 4/172 (2%)
Query: 67 VNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNG 126
V L + +++ LF G + + + +D++TGQ GYGFV ++ +DA+ AI +N
Sbjct: 17 VGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMNM 76
Query: 127 LRLQTKTIKVSYARPSSASIR-DANLYVSGLPKTMTQKELEQLFSQYGRII-TSRILVDQ 184
++L K I+V+ A + ++ AN+++ L + +K L FS +G I+ T +I+ D
Sbjct: 77 IKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDP 136
Query: 185 VTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQ 236
TG S+G FI F ++ AI+ +NGQ PITV +A K +
Sbjct: 137 DTGNSKGYAFINFASFDASDAAIEAMNGQYL--CNRPITVSYAFKKDSKGER 186
Score = 81.6 bits (200), Expect = 1e-15
Identities = 66/245 (26%), Positives = 105/245 (42%), Gaps = 65/245 (26%)
Query: 139 ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFD 198
A P S +DA +YV GL + +++ L +LF Q G ++ + + D+VTG +G GF+ F
Sbjct: 3 AGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFL 62
Query: 199 KRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQA 258
+A+ AIK +N + +LY P R H++
Sbjct: 63 SEEDADYAIKIMN---------------------------MIKLYGKPIRVNKASAHNK- 94
Query: 259 QRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQ 318
LD VG NI F+ NL P+ DE +L+
Sbjct: 95 ---NLD-----------------------VGANI----------FIGNLDPEIDEKLLYD 118
Query: 319 LFGPFGAV-NNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKT 377
F FG + K++RD +T KG+ F+ ++D + AI ++NG L +R + VS+
Sbjct: 119 TFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAF 178
Query: 378 NKAHK 382
K K
Sbjct: 179 KKDSK 183
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,709,694
Number of Sequences: 37866
Number of extensions: 596853
Number of successful extensions: 3238
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 219
Number of HSP's successfully gapped in prelim test: 83
Number of HSP's that attempted gapping in prelim test: 1840
Number of HSP's gapped (non-prelim): 1040
length of query: 383
length of database: 18,247,518
effective HSP length: 104
effective length of query: 279
effective length of database: 14,309,454
effective search space: 3992337666
effective search space used: 3992337666
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.