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Search of human proteins with 115334673
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo
sapiens]
(1203 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo s... 2374 0.0
gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo ... 2333 0.0
gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo sa... 2328 0.0
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 801 0.0
gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens] 649 0.0
gi|5453638 AT rich interactive domain 3B [Homo sapiens] 85 4e-16
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 84 6e-16
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 84 6e-16
gi|62865637 AT rich interactive domain 3C (BRIGHT- like) [Homo s... 83 2e-15
gi|74136549 AT rich interactive domain 5B (MRF1-like) [Homo sapi... 79 3e-14
gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein ... 75 3e-13
gi|71061468 centromere protein E [Homo sapiens] 75 3e-13
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 75 4e-13
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 75 5e-13
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 72 4e-12
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 72 4e-12
gi|47078224 AT rich interactive domain 5A [Homo sapiens] 71 5e-12
gi|56676335 RAP1 interacting factor 1 [Homo sapiens] 71 7e-12
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 70 9e-12
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 70 2e-11
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 70 2e-11
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 69 4e-11
gi|87299628 biorientation of chromosomes in cell division 1-like... 68 6e-11
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 67 8e-11
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 67 8e-11
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 65 4e-10
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 65 4e-10
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 65 5e-10
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 63 1e-09
gi|55956788 nucleolin [Homo sapiens] 63 2e-09
>gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo
sapiens]
Length = 1203
Score = 2374 bits (6152), Expect = 0.0
Identities = 1203/1203 (100%), Positives = 1203/1203 (100%)
Query: 1 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL 60
MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
Sbjct: 1 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL 60
Query: 61 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL 120
RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
Sbjct: 61 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL 120
Query: 121 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS 180
DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
Sbjct: 121 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS 180
Query: 181 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES 240
VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
Sbjct: 181 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES 240
Query: 241 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE 300
ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
Sbjct: 241 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE 300
Query: 301 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID 360
EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
Sbjct: 301 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID 360
Query: 361 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE 420
SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
Sbjct: 361 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE 420
Query: 421 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI 480
KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
Sbjct: 421 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI 480
Query: 481 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK 540
KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
Sbjct: 481 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK 540
Query: 541 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE 600
DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
Sbjct: 541 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE 600
Query: 601 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE 660
IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
Sbjct: 601 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE 660
Query: 661 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE 720
RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE
Sbjct: 661 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE 720
Query: 721 LEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTE 780
LEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTE
Sbjct: 721 LEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTE 780
Query: 781 EVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSS 840
EVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSS
Sbjct: 781 EVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSS 840
Query: 841 ATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF 900
ATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF
Sbjct: 841 ATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF 900
Query: 901 EQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCH 960
EQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCH
Sbjct: 901 EQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCH 960
Query: 961 EVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVK 1020
EVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVK
Sbjct: 961 EVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVK 1020
Query: 1021 SESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNS 1080
SESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNS
Sbjct: 1021 SESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNS 1080
Query: 1081 GLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSEDLPVLDNSNELDNMNSTERISFLQEKLQ 1140
GLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSEDLPVLDNSNELDNMNSTERISFLQEKLQ
Sbjct: 1081 GLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSEDLPVLDNSNELDNMNSTERISFLQEKLQ 1140
Query: 1141 EIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAV 1200
EIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAV
Sbjct: 1141 EIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAV 1200
Query: 1201 ECR 1203
ECR
Sbjct: 1201 ECR 1203
>gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo
sapiens]
Length = 1188
Score = 2333 bits (6046), Expect = 0.0
Identities = 1187/1203 (98%), Positives = 1188/1203 (98%), Gaps = 15/1203 (1%)
Query: 1 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL 60
MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
Sbjct: 1 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL 60
Query: 61 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL 120
RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
Sbjct: 61 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL 120
Query: 121 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS 180
DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
Sbjct: 121 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS 180
Query: 181 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES 240
VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
Sbjct: 181 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES 240
Query: 241 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE 300
ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
Sbjct: 241 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE 300
Query: 301 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID 360
EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
Sbjct: 301 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID 360
Query: 361 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE 420
SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
Sbjct: 361 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE 420
Query: 421 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI 480
KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
Sbjct: 421 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI 480
Query: 481 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK 540
KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
Sbjct: 481 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK 540
Query: 541 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE 600
DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
Sbjct: 541 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE 600
Query: 601 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE 660
IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
Sbjct: 601 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE 660
Query: 661 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE 720
RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE
Sbjct: 661 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE 720
Query: 721 LEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTE 780
LEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTE
Sbjct: 721 LEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTE 780
Query: 781 EVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSS 840
EVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSS
Sbjct: 781 EVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSS 840
Query: 841 ATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF 900
ATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF
Sbjct: 841 ATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF 900
Query: 901 EQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCH 960
EQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCH
Sbjct: 901 EQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCH 960
Query: 961 EVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVK 1020
EVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVK
Sbjct: 961 EVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVK 1020
Query: 1021 SESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNS 1080
SESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNS
Sbjct: 1021 SESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNS 1080
Query: 1081 GLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSEDLPVLDNSNELDNMNSTERISFLQEKLQ 1140
GLMAKKQKRTPKRTSAAAKNEKNGT +ELDNMNSTERISFLQEKLQ
Sbjct: 1081 GLMAKKQKRTPKRTSAAAKNEKNGT---------------DELDNMNSTERISFLQEKLQ 1125
Query: 1141 EIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAV 1200
EIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAV
Sbjct: 1126 EIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAV 1185
Query: 1201 ECR 1203
ECR
Sbjct: 1186 ECR 1188
>gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo
sapiens]
Length = 1257
Score = 2328 bits (6033), Expect = 0.0
Identities = 1195/1257 (95%), Positives = 1199/1257 (95%), Gaps = 54/1257 (4%)
Query: 1 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL 60
MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
Sbjct: 1 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL 60
Query: 61 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL 120
RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
Sbjct: 61 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL 120
Query: 121 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS 180
DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
Sbjct: 121 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS 180
Query: 181 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES 240
VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
Sbjct: 181 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES 240
Query: 241 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE 300
ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
Sbjct: 241 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE 300
Query: 301 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID 360
EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
Sbjct: 301 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID 360
Query: 361 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE 420
SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
Sbjct: 361 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE 420
Query: 421 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI 480
KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
Sbjct: 421 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI 480
Query: 481 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK 540
KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
Sbjct: 481 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK 540
Query: 541 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE 600
DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
Sbjct: 541 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE 600
Query: 601 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE 660
IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
Sbjct: 601 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE 660
Query: 661 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE 720
RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE
Sbjct: 661 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE 720
Query: 721 LEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTE 780
LEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTE
Sbjct: 721 LEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTE 780
Query: 781 EVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSS 840
EVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSS
Sbjct: 781 EVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSS 840
Query: 841 ATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF 900
ATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF
Sbjct: 841 ATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF 900
Query: 901 EQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCH 960
EQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCH
Sbjct: 901 EQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCH 960
Query: 961 EVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVK 1020
EVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVK
Sbjct: 961 EVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVK 1020
Query: 1021 SESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNS 1080
SESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNS
Sbjct: 1021 SESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNS 1080
Query: 1081 GLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSEDLPVLDNSNEL----------------- 1123
GLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSEDLPVLDNS++
Sbjct: 1081 GLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSEDLPVLDNSSKCTPVKHLNVSKPQKLARS 1140
Query: 1124 ------------------DNMNSTER-------------------ISFLQEKLQEIRKYY 1146
+ NS+ R ISFLQEKLQEIRKYY
Sbjct: 1141 PARISPHIKDGEKDKHREKHPNSSPRTYKWSFQLNELDNMNSTERISFLQEKLQEIRKYY 1200
Query: 1147 MSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAVECR 1203
MSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAVECR
Sbjct: 1201 MSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAVECR 1257
>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
Length = 1312
Score = 801 bits (2068), Expect = 0.0
Identities = 547/1346 (40%), Positives = 744/1346 (55%), Gaps = 177/1346 (13%)
Query: 1 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL 60
MKA DEP YLTVGTDVSAKYRGAFCEAKIKT KRLVKVKV + D++T VQDD +KGPL
Sbjct: 1 MKALDEPPYLTVGTDVSAKYRGAFCEAKIKTAKRLVKVKVTFRHDSSTVEVQDDHIKGPL 60
Query: 61 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL 120
+VGAIVE + DG++QEA+I+KLTDASWYTVVFDDGDE+TLRR+SLCLKGERHFAESETL
Sbjct: 61 KVGAIVEVKNLDGAYQEAVINKLTDASWYTVVFDDGDEKTLRRSSLCLKGERHFAESETL 120
Query: 121 DQLPLTNPEHFGTPVIAKKTNRGRRSS-LPVTEDEKEEESSEEEDEDKRRLNDELLGKVV 179
DQLPLTNPEHFGTPVI KKTNRGRRS+ +P +E+ SS +EDED R+ DELLGKVV
Sbjct: 121 DQLPLTNPEHFGTPVIGKKTNRGRRSNHIP---EEESSSSSSDEDEDDRKQIDELLGKVV 177
Query: 180 SVVSAT---ERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILN 236
V + ++ W+PALV+ P C+D+I VKKD LVRSF D KF S+ RKD+ E+
Sbjct: 178 CVDYISLDKKKALWFPALVVCPDCSDEIAVKKDNILVRSFKDGKFTSVPRKDVHEITSDT 237
Query: 237 LPESELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAK 296
P+ + K ++A F K+R +P NWK ++ E SS +++E+ EE D+EKEKE
Sbjct: 238 APKPDAVLKQAFEQALEFHKSRTIPANWKTELKEDSSSSEAEEEE---EEEDDEKEKEDN 294
Query: 297 KTEEEVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGC 356
+EEE E E PEER+NFLQQLYKFMEDRGTPINK PVLGY++LNLFKLFRLV+ GG
Sbjct: 295 SSEEE-EEIEPFPEERENFLQQLYKFMEDRGTPINKRPVLGYRNLNLFKLFRLVHKLGGF 353
Query: 357 DNIDSGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPK 416
DNI+SGAVWKQ+Y DLGIP+LNSAA YNVK AY+KYLYGFEEYCRSANI+F+ + E
Sbjct: 354 DNIESGAVWKQVYQDLGIPVLNSAAGYNVKCAYKKYLYGFEEYCRSANIEFQ-MALPEKV 412
Query: 417 VKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESE-REEIE----LKSPRGRR 471
V ++ K+ E E +K + E + E+K E E NI E +EIE +K G +
Sbjct: 413 VNKQCKECENVKEIKVKEENETEIKEIKMEEERNIIPREEKPIEDEIERKENIKPSLGSK 472
Query: 472 RIARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKK 531
+ + SI ++EK + K D EN D DD T + + + + + +
Sbjct: 473 K--NLLESIPTHSDQEKEVNIKKPEDNENLDDKDDDTTRVDESLNIKVEAEEEKAKSGDE 530
Query: 532 IKKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKI 591
K+ED D + EEEE+ +E EE E D + +EE+ E G KV+V+YGRGK QK+
Sbjct: 531 TNKEEDEDDEEAEEEEEEEEEEEDE---DDDDNNEEEEFECYPPGMKVQVRYGRGKNQKM 587
Query: 592 YEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDS 651
YEASIK ++++ GEVLYLVHY GWNVRYDEW+KAD+I+ P DK PK K +KK KNK D
Sbjct: 588 YEASIKDSDVEGGEVLYLVHYCGWNVRYDEWIKADKIVRPADKNVPKIKHRKKIKNKLDK 647
Query: 652 E--KDEKRDEERQKSKR-GRPPLKSTLSSNMPYGLSKT------------------ANSE 690
E KDEK + K +R +PP ++ S M L T N
Sbjct: 648 EKDKDEKYSPKNCKLRRLSKPPFQTNPSPEMVSKLDLTDAKNSDTAHIKSIEITSILNGL 707
Query: 691 GKSDSCSSDSETED----------ALEKNLINEELSLKDELEKNENLNDDKLDEENP--- 737
S+S + DSE ED E++ I+ + +++L E N L EEN
Sbjct: 708 QASESSAEDSEQEDERGAQDMDNNGKEESKIDHLTNNRNDLISKEEQNSSSLLEENKVHA 767
Query: 738 --KISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTEEVKKE-AEKSPKGKG 794
IS + K +R + + +E L + E V +K ++VKK+ +KS K +
Sbjct: 768 DLVISKPVSKSPERLR-KDIEVLSEDTDYEEDEV------TKKRKDVKKDTTDKSSKPQI 820
Query: 795 RRSKTKDLSL-EIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDEIDQCVKEK 853
+R K + + E +K S G+ E +A + E ++N + SS+ EDE + K
Sbjct: 821 KRGKRRYCNTEECLKTGSPGKKEE------KAKNKESLCMENSSNSSSDEDEEETKAKMT 874
Query: 854 KLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNFEQHFERENEGMPS 913
K K G K +R + V+++R S+ + L + +R++
Sbjct: 875 PTK-KYNGLEEKRKSLRTTGFYSGFSEVAEKRIKLLNNSD--ERLQNSRAKDRKDVWSSI 931
Query: 914 LIAESNQCIQQLTSERFDSPAEETVNIPLKED---EDAMPLIGPETLVCHEVDLDDLD-- 968
+ +++L S+ D+ A + P E+ E+++ + E V+L+
Sbjct: 932 QGQWPKKTLKELFSDS-DTEAAASPPHPAPEEGVAEESLQTVAEEESCSPSVELEKPPPV 990
Query: 969 EKDKTSIEDVAVE---------SSESNSLVSIPPALPPV-----------VQHNFSVASP 1008
D IE+ VE SS SNS+++ PP P Q + +V+ P
Sbjct: 991 NVDSKPIEEKTVEVNDRKAEFPSSGSNSVLNTPPTTPESPSSVTVTEGSRQQSSVTVSEP 1050
Query: 1009 LTLSQDESRSVKSESDITIEVDSIAEESQEGLCE-RESANGFETNVASGTCSIIVQERES 1067
L +Q+E RS+KSE+D TIEVDS+A E Q+ E S GF+ +V+S + + E E
Sbjct: 1051 LAPNQEEVRSIKSETDSTIEVDSVAGELQDLQSEGNSSPAGFDASVSSSSSN--QPEPEH 1108
Query: 1068 REK---GQKRPSDG-NSGLMAKKQKRTPKRTSAAAKNEKNGTG-QSSDSEDLPVLDNSNE 1122
EK GQKR D G +KKQKR+ K T N+K G G SSDSE+L ++ +
Sbjct: 1109 PEKACTGQKRVKDAQGGGSSSKKQKRSHKAT--VVNNKKKGKGTNSSDSEELSAGESITK 1166
Query: 1123 LDNMNST-------------------------ERISFLQEKLQEIRKYY----------- 1146
+ S ++ L+E + K Y
Sbjct: 1167 SQPVKSVSTGMKSHSTKSPARTQSPGKCGKNGDKDPDLKEPSNRLPKVYKWSFQMSDLEN 1226
Query: 1147 MSLKSEVATIDRRRKRLKK---------------------KDREVSHAGASMSSASSD-- 1183
M+ + + + + ++K K+RE + +S SS SS
Sbjct: 1227 MTSAERITILQEKLQEIRKHYLSLKSEVASIDRRRKRLKKKERESAATSSSSSSPSSSSI 1286
Query: 1184 ------TGMSPSSSSPPQNVLAVECR 1203
T PS SS QN ++VECR
Sbjct: 1287 TAAVMLTLAEPSMSSASQNGMSVECR 1312
>gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens]
Length = 1226
Score = 649 bits (1674), Expect = 0.0
Identities = 481/1313 (36%), Positives = 685/1313 (52%), Gaps = 197/1313 (15%)
Query: 1 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL 60
MKA DEP YLTVGTDVSAKYRGAFCEAKIKT KRLVKVKV + D++T VQDD +KGPL
Sbjct: 1 MKALDEPPYLTVGTDVSAKYRGAFCEAKIKTAKRLVKVKVTFRHDSSTVEVQDDHIKGPL 60
Query: 61 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL 120
+VGAIVE + DG++QEA+I+KLTDASWYTVVFDDGDE+TLRR+SLCLKGERHFAESETL
Sbjct: 61 KVGAIVEVKNLDGAYQEAVINKLTDASWYTVVFDDGDEKTLRRSSLCLKGERHFAESETL 120
Query: 121 DQLPLTNPEHFGTPVIAKKTNRGRRSS-LPVTEDEKEEESSEEEDEDKRRLNDELLGKVV 179
DQLPLTNPEHFGTPVI KKTNRGRRS+ +P +E+ SS +EDED R+ DELLGKVV
Sbjct: 121 DQLPLTNPEHFGTPVIGKKTNRGRRSNHIP---EEESSSSSSDEDEDDRKQIDELLGKVV 177
Query: 180 SVVSAT---ERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILN 236
V + ++ W+PALV+ P C+D+I VKKD LVRSF D KF S+ RKD+ E+
Sbjct: 178 CVDYISLDKKKALWFPALVVCPDCSDEIAVKKDNILVRSFKDGKFTSVPRKDVHEITSDT 237
Query: 237 LPESELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAK 296
P+ + K ++A F K+R +P NWK ++ E SS +++E+ EE D+EKEKE
Sbjct: 238 APKPDAVLKQAFEQALEFHKSRTIPANWKTELKEDSSSSEAEEEE---EEEDDEKEKEDN 294
Query: 297 KTEEEVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGC 356
+EEE E E PEER+NFLQQLYKFMEDRGTPINK PVLGY++LNLFKLFRLV+ GG
Sbjct: 295 SSEEE-EEIEPFPEERENFLQQLYKFMEDRGTPINKRPVLGYRNLNLFKLFRLVHKLGGF 353
Query: 357 DNIDSGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPK 416
DNI+SGAVWKQ+Y DLGIP+LNSAA YNVK AY+KYLYGFEEYCRSANI+F+ + E
Sbjct: 354 DNIESGAVWKQVYQDLGIPVLNSAAGYNVKCAYKKYLYGFEEYCRSANIEFQ-MALPEKV 412
Query: 417 VKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESE-REEIE----LKSPRGRR 471
V ++ K+ E E +K + E + E+K E E NI E +EIE +K G +
Sbjct: 413 VNKQCKECENVKEIKVKEENETEIKEIKMEEERNIIPREEKPIEDEIERKENIKPSLGSK 472
Query: 472 RIARDVNSIKKEIEEEKTEDKLKDNDTEN-KDVDDDYETAEKKENELLLGRKNTPKQKEK 530
+ + SI ++EK + K D EN D DDD ++ N + + K
Sbjct: 473 K--NLLESIPTHSDQEKEVNIKKPEDNENLDDKDDDTTRVDESLNIKVEAEEEKAKSGYD 530
Query: 531 KIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEE-DMEPCLTGTKVKVKYGRGKTQ 589
+ K + + +D+ K + R++ ++K D E ++DE+ + C K + +
Sbjct: 531 EWIKADKIVRPADKNVPKIKHRKKIKNKLDKEKDKDEKYSPKNCKLRRLSKPPFQTNPSP 590
Query: 590 KIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKE 649
++ + ++ D + H +K+ I L+ + + E
Sbjct: 591 EM----VSKLDLTDAKNSDTAH-----------IKSIEITSILN------GLQASESSAE 629
Query: 650 DSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKN 709
DSE++++R + + L++N +SK + + LE+N
Sbjct: 630 DSEQEDERGAQDMDNNGKEESKIDHLTNNRNDLISK------------EEQNSSSLLEEN 677
Query: 710 LINEELSLKDELEKN-ENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQI 768
++ +L + + K+ E L D +E L + E
Sbjct: 678 KVHADLVISKPVSKSPERLRKD------------------------IEVLSEDTDYEEDE 713
Query: 769 VQIFGNKMEKTEEVKKE-AEKSPKGKGRRSKTKDLSL-EIIKISSFGQNEAGSEPHIEAH 826
V +K ++VKK+ +KS K + +R K + + E +K S G+ E +A
Sbjct: 714 V------TKKRKDVKKDTTDKSSKPQIKRGKRRYCNTEECLKTGSPGKKEE------KAK 761
Query: 827 SLELSSLDNKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERT 886
+ E ++N + SS+ EDE + K K K G K +R + V+++R
Sbjct: 762 NKESLCMENSSNSSSDEDEEETKAKMTPTK-KYNGLEEKRKSLRTTGFYSGFSEVAEKRI 820
Query: 887 SDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKED- 945
S+ + L + +R++ + +++L S+ D+ A + P E+
Sbjct: 821 KLLNNSD--ERLQNSRAKDRKDVWSSIQGQWPKKTLKELFSDS-DTEAAASPPHPAPEEG 877
Query: 946 --EDAMPLIGPETLVCHEVDLDDLD--EKDKTSIEDVAVE---------SSESNSLVSIP 992
E+++ + E V+L+ D IE+ VE SS SNS+++ P
Sbjct: 878 VAEESLQTVAEEESCSPSVELEKPPPVNVDSKPIEEKTVEVNDRKAEFPSSGSNSVLNTP 937
Query: 993 PALPPV-----------VQHNFSVASPLTLSQDESRSVKSESDITIEVDSIAEESQEGLC 1041
P P Q + +V+ PL +Q+E RS+KSE+D TIEVDS+A E Q+
Sbjct: 938 PTTPESPSSVTVTEGSRQQSSVTVSEPLAPNQEEVRSIKSETDSTIEVDSVAGELQDLQS 997
Query: 1042 E-RESANGFETNVASGTCSIIVQERESREK---GQKRPSDG-NSGLMAKKQKRTPKRTSA 1096
E S GF+ +V+S + + E E EK GQKR D G +KKQKR+ K T
Sbjct: 998 EGNSSPAGFDASVSSSSSN--QPEPEHPEKACTGQKRVKDAQGGGSSSKKQKRSHKAT-- 1053
Query: 1097 AAKNEKNGTG-QSSDSEDLPVLDNSNELDNMNST-------------------------E 1130
N+K G G SSDSE+L ++ + + S +
Sbjct: 1054 VVNNKKKGKGTNSSDSEELSAGESITKSQPVKSVSTGMKSHSTKSPARTQSPGKCGKNGD 1113
Query: 1131 RISFLQEKLQEIRKYY-----------MSLKSEVATIDRRRKRLKK-------------- 1165
+ L+E + K Y M+ + + + + ++K
Sbjct: 1114 KDPDLKEPSNRLPKVYKWSFQMSDLENMTSAERITILQEKLQEIRKHYLSLKSEVASIDR 1173
Query: 1166 -------KDREVSHAGASMSSASSD--------TGMSPSSSSPPQNVLAVECR 1203
K+RE + +S SS SS T PS SS QN ++VECR
Sbjct: 1174 RRKRLKKKERESAATSSSSSSPSSSSITAAVMLTLAEPSMSSASQNGMSVECR 1226
>gi|5453638 AT rich interactive domain 3B [Homo sapiens]
Length = 560
Score = 85.1 bits (209), Expect = 4e-16
Identities = 61/198 (30%), Positives = 101/198 (51%), Gaps = 32/198 (16%)
Query: 219 SKFYSIARKDIKEVDILNLPESELSTKPGL---------------QKASIFLKTRVVPDN 263
SK++ + + + D P S L PGL KAS + T P N
Sbjct: 119 SKYFHVQK--VARQDPRVAPMSNLLPAPGLPPHGQQAKEDHTKDASKASPSVSTAGQP-N 175
Query: 264 WKMDISEILESSS----SDDEDGPAEENDEEKEKEAKKTEEEVPEEELDPEERDNFLQQL 319
W +D E L+ + SDD DG + +E + ++ E + DPE ++ FL L
Sbjct: 176 WNLD--EQLKQNGGLAWSDDADGG-------RGREISRDFAKLYELDGDPERKE-FLDDL 225
Query: 320 YKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNIDSGAVWKQIYMDLGIPILNS 379
+ FM+ RGTPIN+ P++ + L+L+ L++LV +GG I + +W++I L +P +
Sbjct: 226 FVFMQKRGTPINRIPIMAKQILDLYMLYKLVTEKGGLVEIINKKIWREITKGLNLPTSIT 285
Query: 380 AASYNVKTAYRKYLYGFE 397
+A++ ++T Y KYLY +E
Sbjct: 286 SAAFTLRTQYMKYLYAYE 303
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 84.3 bits (207), Expect = 6e-16
Identities = 136/685 (19%), Positives = 257/685 (37%), Gaps = 141/685 (20%)
Query: 409 TVHHHEPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPR 468
T H K + K++ ++ +E+ K +E + ++K E ENI ++ +SE + + +
Sbjct: 713 TKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEE-RENIPTDKDSEFTSLGMSAIE 771
Query: 469 GRRRIARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQK 528
+ ++ ++KEI+ EK E +K++ K
Sbjct: 772 E----SIGLHLVEKEIDIEKQEKHIKES-------------------------------K 796
Query: 529 EKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKT 588
EK K+ + +KD ++ E K+ E+E+ + K + + E+D+ D+ C+ K K K T
Sbjct: 797 EKPEKRSQIKEKDIEKMERKTFEKEK-KIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHT 855
Query: 589 QKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNK 648
+K ++ KS + K ++K ++K K
Sbjct: 856 EKCHKEGEKSKNTA----------------------------AIKKTDDREKSREKMDRK 887
Query: 649 EDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEK 708
D EK EK + ++ K+ S N Y S+ ++ K ++ D
Sbjct: 888 HDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESI 947
Query: 709 NLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLET----------- 757
N+ N + +++E +K+ ++ +K E P L ++T+ +PL+T
Sbjct: 948 NITNSK-HIQEE-KKSSIVDGNKAQHEKP------LSLKEKTKDEPLKTPDGKEKDKKDK 999
Query: 758 ---LKLEVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQ 814
E +++ +QI K+E K + + SP K R K K L + + +SF
Sbjct: 1000 DIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSF-- 1057
Query: 815 NEAGSEPHIEAHSLELSSLDNKNFSSATEDEIDQ-----CVKEK---KLKRKILGQSSPE 866
E + LE+ K+ + E ++ C++ K K K K S
Sbjct: 1058 -----ERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKN 1112
Query: 867 KKIRIENGMEMTNTVSQERTSD----------------CIGSEGMKNLNFEQHFERENEG 910
K++ E+T+ ++E+ +G + N R
Sbjct: 1113 KELTRSKSSEVTDAYTKEKQPKDAVSNRSQSVDTKNVMTLGKSSFVSDNSLNRSPRSENE 1172
Query: 911 MPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCHEVDLDDLDEK 970
P L + S I +SE T P++ D D M L E +
Sbjct: 1173 KPGLSSRSVSMISVASSEDSCHTTVTTPRPPVEYDSDFM-------LESSESQMSFSQSP 1225
Query: 971 DKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVKSESDITIEV- 1029
+ + A+ E +SL +P + P + S + + S ++ + + SE TIEV
Sbjct: 1226 FLSIAKSPALHERELDSLADLPERIKPPYANRLSTSHLRSSSVEDVKLIISEGRPTIEVR 1285
Query: 1030 ---------------DSIAEESQEG 1039
+I+EES +G
Sbjct: 1286 RCSMPSVICEHTKQFQTISEESNQG 1310
Score = 57.4 bits (137), Expect = 8e-08
Identities = 162/829 (19%), Positives = 297/829 (35%), Gaps = 170/829 (20%)
Query: 419 EEKKDLEESMEEALKLDQEMPLT----------EVKSEPEENIDSNSESEREEIELKSPR 468
E D+ E+ E L L +E+PL+ E +S ++D N +SE E+ L
Sbjct: 262 ERPVDVAETEELELLLKREVPLSDDDESYTDSEEAQSVNPSSVDENIDSETEKDSLICE- 320
Query: 469 GRRRIARDVNSIKKEIEEEKTEDKLKDNDTE--NKDVDDDY--ETAEKKENELLLGRKNT 524
++ + K + E + KD+D E NK +DD + ++KENE + +
Sbjct: 321 -----SKQILPSKTPLPSALDEYEFKDDDDEEINKMIDDRHILRKEQRKENEPEAEKTHL 375
Query: 525 PKQKEK-------KIKKQEDSD---KDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCL 574
++EK K KKQ+ S ++ +E++ + ++ + C E DM+
Sbjct: 376 FAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQ--- 432
Query: 575 TGTKVKVKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDK 634
T+K Y S GE
Sbjct: 433 -------------TKKEYVVS--------GE----------------------------- 442
Query: 635 GGPKKKQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKST-LSSNMPYGLSKTANSEGKS 693
KQK K K K ++ K ++E ++ K G+ + T L+ N S+ EG
Sbjct: 443 ----HKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNF 498
Query: 694 DSCSSDSETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQ 753
S + + +L I+ S K +E K S + +E+ +T +
Sbjct: 499 RKSFSPKD-DTSLHLFHISTGKSPKHSCGLSE------------KQSTPLKQEHTKTCLS 545
Query: 754 PLETLKLEVGENEQIVQIFGNKMEKTEE---VKKEAEKSPKGKGRRSKTKDLSLEIIKIS 810
P G +E +Q + + TE + + KS K K + KD LE + S
Sbjct: 546 P--------GSSEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQKDFHLEFGEKS 597
Query: 811 SFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDEIDQCVKEK-KLKRKILGQSSP---- 865
+ + P E L +D K + + ++ +EK K K++I G+
Sbjct: 598 NAKIKDEDHSPTFENSDCTLKKMD-KEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTK 656
Query: 866 ------EKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF-----------------EQ 902
++ + + N + T D + ++L E+
Sbjct: 657 DSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEK 716
Query: 903 HFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPL---IGPETLVC 959
H +E + + E+ EE NIP +D + L E++
Sbjct: 717 HVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGL 776
Query: 960 HEVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSV 1019
H V+ + EK + I++ + E E S + + + + F + + E +S
Sbjct: 777 HLVEKEIDIEKQEKHIKE-SKEKPEKRSQIK-EKDIEKMERKTFEKEKKI---KHEHKSE 831
Query: 1020 KSESDITIEVDSIAEESQ-----EGLCERESANGFETNVASGTCSIIVQERESREKGQKR 1074
K + D++ VD I E+ + C +E T T + K K
Sbjct: 832 KDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKE 891
Query: 1075 PSDGNSGLMAKKQKRTPKRTSAAAKN---EKNGTGQSSDSE-DLPVLDNSNELDNMNSTE 1130
+ L K+K ++ + + N K+ G++ + + +L + S + +++N T
Sbjct: 892 KPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITN 951
Query: 1131 RISFLQEKLQEI-------RKYYMSLKSE-----VATIDRRRKRLKKKD 1167
+EK I + +SLK + + T D + K K KD
Sbjct: 952 SKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKD 1000
Score = 44.7 bits (104), Expect = 5e-04
Identities = 96/490 (19%), Positives = 173/490 (35%), Gaps = 92/490 (18%)
Query: 418 KEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDV 477
K E+ D+ + M+E + +++P T S EE RD
Sbjct: 42 KIERSDVSKEMKEKSSMKRKLPFTISPSRNEE-------------------------RDS 76
Query: 478 NSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLL----------GRKNTPKQ 527
++ K+ E++KT+ + + + + Y +E+K+ LL+ N P Q
Sbjct: 77 DTEKEGPEKKKTKKEAGNKKSTPVSILFGYPLSERKQMALLMQMTARDNSPDSTPNHPSQ 136
Query: 528 KEKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVK----- 582
KK S ++ K ER ET + + ++ E G V VK
Sbjct: 137 TTPAQKKTPSSSSRQKDKVNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGW 196
Query: 583 -----------YGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWP 631
Y K A + + +DD L+ G D +
Sbjct: 197 TPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSG---------HRDIVKLL 247
Query: 632 LDKGGPKKKQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEG 691
L GG + K + D + EE + + PL S +++ N
Sbjct: 248 LRHGGNPFQANKHGERPVDVAE----TEELELLLKREVPLSDDDESYTDSEEAQSVNPSS 303
Query: 692 KSDSCSSDSETEDAL--EKNLINEELSLKDELEKNENLNDDKLDEENPKI--SAHILKEN 747
++ S++E + + K ++ + L L++ E +DD DEE K+ HIL++
Sbjct: 304 VDENIDSETEKDSLICESKQILPSKTPLPSALDEYEFKDDD--DEEINKMIDDRHILRKE 361
Query: 748 DRTQMQPLETLKLEVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEII 807
R + +P + EKT K+ EK+ K +SK + S +
Sbjct: 362 QRKENEP--------------------EAEKTHLFAKQ-EKAFYPKSFKSKKQKPSRVLY 400
Query: 808 KISSFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDEIDQCVKEK-KLKRKILGQSSPE 866
+ EA I + N + + E + K+K K+KRK+ Q+ +
Sbjct: 401 SSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLKNQNKNK 460
Query: 867 KKIRIENGME 876
+ ++ E
Sbjct: 461 ENQELKQEKE 470
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 84.3 bits (207), Expect = 6e-16
Identities = 136/685 (19%), Positives = 257/685 (37%), Gaps = 141/685 (20%)
Query: 409 TVHHHEPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPR 468
T H K + K++ ++ +E+ K +E + ++K E ENI ++ +SE + + +
Sbjct: 736 TKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEE-RENIPTDKDSEFTSLGMSAIE 794
Query: 469 GRRRIARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQK 528
+ ++ ++KEI+ EK E +K++ K
Sbjct: 795 E----SIGLHLVEKEIDIEKQEKHIKES-------------------------------K 819
Query: 529 EKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKT 588
EK K+ + +KD ++ E K+ E+E+ + K + + E+D+ D+ C+ K K K T
Sbjct: 820 EKPEKRSQIKEKDIEKMERKTFEKEK-KIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHT 878
Query: 589 QKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNK 648
+K ++ KS + K ++K ++K K
Sbjct: 879 EKCHKEGEKSKNTA----------------------------AIKKTDDREKSREKMDRK 910
Query: 649 EDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEK 708
D EK EK + ++ K+ S N Y S+ ++ K ++ D
Sbjct: 911 HDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESI 970
Query: 709 NLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLET----------- 757
N+ N + +++E +K+ ++ +K E P L ++T+ +PL+T
Sbjct: 971 NITNSK-HIQEE-KKSSIVDGNKAQHEKP------LSLKEKTKDEPLKTPDGKEKDKKDK 1022
Query: 758 ---LKLEVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQ 814
E +++ +QI K+E K + + SP K R K K L + + +SF
Sbjct: 1023 DIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSF-- 1080
Query: 815 NEAGSEPHIEAHSLELSSLDNKNFSSATEDEIDQ-----CVKEK---KLKRKILGQSSPE 866
E + LE+ K+ + E ++ C++ K K K K S
Sbjct: 1081 -----ERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKN 1135
Query: 867 KKIRIENGMEMTNTVSQERTSD----------------CIGSEGMKNLNFEQHFERENEG 910
K++ E+T+ ++E+ +G + N R
Sbjct: 1136 KELTRSKSSEVTDAYTKEKQPKDAVSNRSQSVDTKNVMTLGKSSFVSDNSLNRSPRSENE 1195
Query: 911 MPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCHEVDLDDLDEK 970
P L + S I +SE T P++ D D M L E +
Sbjct: 1196 KPGLSSRSVSMISVASSEDSCHTTVTTPRPPVEYDSDFM-------LESSESQMSFSQSP 1248
Query: 971 DKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVKSESDITIEV- 1029
+ + A+ E +SL +P + P + S + + S ++ + + SE TIEV
Sbjct: 1249 FLSIAKSPALHERELDSLADLPERIKPPYANRLSTSHLRSSSVEDVKLIISEGRPTIEVR 1308
Query: 1030 ---------------DSIAEESQEG 1039
+I+EES +G
Sbjct: 1309 RCSMPSVICEHTKQFQTISEESNQG 1333
Score = 57.4 bits (137), Expect = 8e-08
Identities = 162/829 (19%), Positives = 297/829 (35%), Gaps = 170/829 (20%)
Query: 419 EEKKDLEESMEEALKLDQEMPLT----------EVKSEPEENIDSNSESEREEIELKSPR 468
E D+ E+ E L L +E+PL+ E +S ++D N +SE E+ L
Sbjct: 285 ERPVDVAETEELELLLKREVPLSDDDESYTDSEEAQSVNPSSVDENIDSETEKDSLICE- 343
Query: 469 GRRRIARDVNSIKKEIEEEKTEDKLKDNDTE--NKDVDDDY--ETAEKKENELLLGRKNT 524
++ + K + E + KD+D E NK +DD + ++KENE + +
Sbjct: 344 -----SKQILPSKTPLPSALDEYEFKDDDDEEINKMIDDRHILRKEQRKENEPEAEKTHL 398
Query: 525 PKQKEK-------KIKKQEDSD---KDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCL 574
++EK K KKQ+ S ++ +E++ + ++ + C E DM+
Sbjct: 399 FAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQ--- 455
Query: 575 TGTKVKVKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDK 634
T+K Y S GE
Sbjct: 456 -------------TKKEYVVS--------GE----------------------------- 465
Query: 635 GGPKKKQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKST-LSSNMPYGLSKTANSEGKS 693
KQK K K K ++ K ++E ++ K G+ + T L+ N S+ EG
Sbjct: 466 ----HKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNF 521
Query: 694 DSCSSDSETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQ 753
S + + +L I+ S K +E K S + +E+ +T +
Sbjct: 522 RKSFSPKD-DTSLHLFHISTGKSPKHSCGLSE------------KQSTPLKQEHTKTCLS 568
Query: 754 PLETLKLEVGENEQIVQIFGNKMEKTEE---VKKEAEKSPKGKGRRSKTKDLSLEIIKIS 810
P G +E +Q + + TE + + KS K K + KD LE + S
Sbjct: 569 P--------GSSEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQKDFHLEFGEKS 620
Query: 811 SFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDEIDQCVKEK-KLKRKILGQSSP---- 865
+ + P E L +D K + + ++ +EK K K++I G+
Sbjct: 621 NAKIKDEDHSPTFENSDCTLKKMD-KEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTK 679
Query: 866 ------EKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF-----------------EQ 902
++ + + N + T D + ++L E+
Sbjct: 680 DSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEK 739
Query: 903 HFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPL---IGPETLVC 959
H +E + + E+ EE NIP +D + L E++
Sbjct: 740 HVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGL 799
Query: 960 HEVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSV 1019
H V+ + EK + I++ + E E S + + + + F + + E +S
Sbjct: 800 HLVEKEIDIEKQEKHIKE-SKEKPEKRSQIK-EKDIEKMERKTFEKEKKI---KHEHKSE 854
Query: 1020 KSESDITIEVDSIAEESQ-----EGLCERESANGFETNVASGTCSIIVQERESREKGQKR 1074
K + D++ VD I E+ + C +E T T + K K
Sbjct: 855 KDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKE 914
Query: 1075 PSDGNSGLMAKKQKRTPKRTSAAAKN---EKNGTGQSSDSE-DLPVLDNSNELDNMNSTE 1130
+ L K+K ++ + + N K+ G++ + + +L + S + +++N T
Sbjct: 915 KPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITN 974
Query: 1131 RISFLQEKLQEI-------RKYYMSLKSE-----VATIDRRRKRLKKKD 1167
+EK I + +SLK + + T D + K K KD
Sbjct: 975 SKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKD 1023
Score = 50.4 bits (119), Expect = 1e-05
Identities = 98/491 (19%), Positives = 180/491 (36%), Gaps = 71/491 (14%)
Query: 418 KEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIAR-D 476
K E+ D+ + M+E + +++P T P N + +S+++ + G R I+
Sbjct: 42 KIERSDVSKEMKEKSSMKRKLPFT---ISPSRNEERDSDTDSDPGHTSENWGERLISSYR 98
Query: 477 VNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLL----------GRKNTPK 526
S K+ E++KT+ + + + + Y +E+K+ LL+ N P
Sbjct: 99 TYSEKEGPEKKKTKKEAGNKKSTPVSILFGYPLSERKQMALLMQMTARDNSPDSTPNHPS 158
Query: 527 QKEKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVK---- 582
Q KK S ++ K ER ET + + ++ E G V VK
Sbjct: 159 QTTPAQKKTPSSSSRQKDKVNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAG 218
Query: 583 ------------YGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIW 630
Y K A + + +DD L+ G D +
Sbjct: 219 WTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSG---------HRDIVKL 269
Query: 631 PLDKGGPKKKQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSE 690
L GG + K + D + EE + + PL S +++ N
Sbjct: 270 LLRHGGNPFQANKHGERPVDVAE----TEELELLLKREVPLSDDDESYTDSEEAQSVNPS 325
Query: 691 GKSDSCSSDSETEDAL--EKNLINEELSLKDELEKNENLNDDKLDEENPKI--SAHILKE 746
++ S++E + + K ++ + L L++ E +DD DEE K+ HIL++
Sbjct: 326 SVDENIDSETEKDSLICESKQILPSKTPLPSALDEYEFKDDD--DEEINKMIDDRHILRK 383
Query: 747 NDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEI 806
R + +P + EKT K+ EK+ K +SK + S +
Sbjct: 384 EQRKENEP--------------------EAEKTHLFAKQ-EKAFYPKSFKSKKQKPSRVL 422
Query: 807 IKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDEIDQCVKEK-KLKRKILGQSSP 865
+ EA I + N + + E + K+K K+KRK+ Q+
Sbjct: 423 YSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLKNQNKN 482
Query: 866 EKKIRIENGME 876
++ ++ E
Sbjct: 483 KENQELKQEKE 493
>gi|62865637 AT rich interactive domain 3C (BRIGHT- like) [Homo
sapiens]
Length = 412
Score = 82.8 bits (203), Expect = 2e-15
Identities = 52/171 (30%), Positives = 84/171 (49%), Gaps = 34/171 (19%)
Query: 260 VPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEEEVPEE-------------- 305
+PD+ + E + +E+ AEE DEEK +EA EE E
Sbjct: 32 LPDHRTLQAPEGALGNVGAEEEEDAEE-DEEKREEAGAEEEAAEESRPGAQGPSSPSSQP 90
Query: 306 ------------------ELDPE-ERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKL 346
ELD + +R FL L+ FM+ RGTP+N+ P++ + L+L+ L
Sbjct: 91 PGLHPHEWTYEEQFKQLYELDADPKRKEFLDDLFSFMQKRGTPVNRVPIMAKQVLDLYAL 150
Query: 347 FRLVYHQGGCDNIDSGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFE 397
FRLV +GG + + VW+++ L +P ++A++ ++T Y KYLY +E
Sbjct: 151 FRLVTAKGGLVEVINRKVWREVTRGLSLPTTITSAAFTLRTQYMKYLYPYE 201
>gi|74136549 AT rich interactive domain 5B (MRF1-like) [Homo
sapiens]
Length = 1188
Score = 78.6 bits (192), Expect = 3e-14
Identities = 65/285 (22%), Positives = 124/285 (43%), Gaps = 66/285 (23%)
Query: 296 KKTEEEVPEEELDPEERDN---FLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYH 352
K + EE P+ + E R + FL LYK+M++R TPI + P LG+K +NL+ +F+
Sbjct: 302 KVSNEEKPKVAIGEECRADEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQK 361
Query: 353 QGGCDNIDSGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHH 412
GG + I + WK IY +LG +++A+ + Y + + +E +
Sbjct: 362 LGGYETITARRQWKHIYDELGGNPGSTSAATCTRRHYERLILPYERF------------- 408
Query: 413 HEPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRR 472
+K +++ PL +K +EN +E++ + G +R
Sbjct: 409 -------------------IKGEEDKPLPPIKPRKQENSSQENENKTK------VSGTKR 443
Query: 473 IARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPK-----Q 527
I ++ KKE K+N + +D + + ++KE E L+ +K+ P+
Sbjct: 444 IKHEIPKSKKE----------KENAPKPQDA-AEVSSEQEKEQETLISQKSIPEPLPAAD 492
Query: 528 KEKKIKKQED---------SDKDSDEEEEKSQEREETESKCDSEG 563
+KKI+ ++ D + D E ++ E+ + +G
Sbjct: 493 MKKKIEGYQEFSAKPLASRVDPEKDNETDQGSNSEKVAEEAGEKG 537
>gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein
[Homo sapiens]
Length = 593
Score = 75.5 bits (184), Expect = 3e-13
Identities = 38/115 (33%), Positives = 70/115 (60%), Gaps = 5/115 (4%)
Query: 283 PAEENDEEKEKEAKKTEEEVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLN 342
P + D E++ K ++ E + DP+ ++ FL L+ FM+ RGTP+N+ P++ + L+
Sbjct: 217 PPDHGDWTYEEQFK----QLYELDGDPKRKE-FLDDLFSFMQKRGTPVNRIPIMAKQVLD 271
Query: 343 LFKLFRLVYHQGGCDNIDSGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFE 397
LF L+ LV +GG + + +W++I L +P ++A++ ++T Y KYLY +E
Sbjct: 272 LFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYE 326
Score = 32.0 bits (71), Expect = 3.6
Identities = 18/67 (26%), Positives = 31/67 (46%)
Query: 505 DDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGE 564
+D ++E+ G +P + + ++ D SDE+ + E EE E + E
Sbjct: 82 EDGPPGSEEEDAAREGTPGSPGRGREGPGEEHFEDMASDEDMKPKWEEEEMEEDLGEDEE 141
Query: 565 EDEEDME 571
E+EED E
Sbjct: 142 EEEEDYE 148
Score = 30.8 bits (68), Expect = 8.1
Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 11/48 (22%)
Query: 525 PKQKEKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEP 572
PK +E+++ +ED +D +EEEE ++ EE EEDEE + P
Sbjct: 125 PKWEEEEM--EEDLGEDEEEEEEDYEDEEE---------EEDEEGLGP 161
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 75.5 bits (184), Expect = 3e-13
Identities = 198/1047 (18%), Positives = 417/1047 (39%), Gaps = 205/1047 (19%)
Query: 229 IKEVDILNLP-ESELSTKPGL--------QKASIFLKTRVVPDNWKMDISEILESSSSDD 279
+K ++ N E+ELS+K L +K ++ ++ + +N KMD+S LES
Sbjct: 563 VKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKL-ENIKMDLSYSLESIEDPK 621
Query: 280 EDGPAEENDEEKEKEAKKTEEEVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYK 339
+ + E +AK+ + E L+ +E+ L YK ME+
Sbjct: 622 QMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMEN-------------- 667
Query: 340 DLNLFKLFRLVYHQGGCDNIDSGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEY 399
D+ L++ K++ +DL + +++N T + G
Sbjct: 668 DIQLYQ--------------SQLEAKKKMQVDLEKEL---QSAFNEITKLTSLIDGKVPK 710
Query: 400 CRSANIQFRTVHHHEPKVKEEKKDLEESMEEALKLDQEMPL-TEVKSEPEE--NIDSNSE 456
N++ E K+ + +K+L + +EE L +E+ L +E+KS P E + +
Sbjct: 711 DLLCNLEL------EGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQ 764
Query: 457 SEREEIELKSPRGRRRIARDVNS---IKKEIEE-EKTEDKLKDNDTENKDVDDDYETAE- 511
+ EE+ + + + + V+ ++ +EE KT+D L + K D +++ +
Sbjct: 765 DKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKT 824
Query: 512 -----KKENELLLGRKNTPKQKEKKIKKQEDSDKDS------------DEEEEKSQEREE 554
+++ +++L Q+ + K+ S E +EK++E +E
Sbjct: 825 LHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQE 884
Query: 555 TESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYG 614
++ + E+ E T + K Q + E + E DD + L
Sbjct: 885 RLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQL------- 937
Query: 615 WNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRD--EERQKSKRGRPPLK 672
E ++ +R K N +++ R+ E ++ + LK
Sbjct: 938 -----QESLQIER--------DQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLK 984
Query: 673 STLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLIN----EELSLKDELEKNENLN 728
S +S + L N+ ET+D ++ ++ ++L K+ ++
Sbjct: 985 SKISEEVSRNLHMEENT----------GETKDEFQQKMVGIDKKQDLEAKNTQTLTADVK 1034
Query: 729 DDKLDEENPKISAHILKENDRTQM-----QPLETLKLEVGEN-------EQIVQIFGNKM 776
D+++ E+ KI + I ++N+ QM E LK ++ EN ++ +++ G+++
Sbjct: 1035 DNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDEL 1094
Query: 777 EKTEEV---------KKEAEKSP------------KGKGRRSKTKDLSL----------- 804
+K +E+ KKE E S K K ++ + K L
Sbjct: 1095 KKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQ 1154
Query: 805 ----EIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDEIDQCVKEKKLKRKIL 860
EI + + +N+ + H+E LEL+ N+N+ +E+ KE+K+ +++
Sbjct: 1155 KKINEIENLKNELKNKELTLEHMETERLELAQKLNENY-----EEVKSITKERKVLKEL- 1208
Query: 861 GQSSPEKKIRIENG----MEMTNTVSQERTSDCIGSEGMKNLNFEQHFERENEGMPSLIA 916
Q S E + G +E T ++E + +++ ++H E +E S+
Sbjct: 1209 -QKSFETERDHLRGYIREIEATGLQTKEELK-------IAHIHLKEHQETIDELRRSVSE 1260
Query: 917 ESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLI-----GPETLVCHEVDLDDLDEKD 971
++ Q I E+ + +E + + L E+++ +P + ET+ E+ + KD
Sbjct: 1261 KTAQIINTQDLEKSHTKLQEEIPV-LHEEQELLPNVKEVSETQETMNELELLTEQSTTKD 1319
Query: 972 KTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVKSESDITIEVDS 1031
T++ + +E N Q + LT +D +++K + ++ D
Sbjct: 1320 STTLARIEMERLRLNE----------KFQESQEEIKSLTKERDNLKTIKEA--LEVKHDQ 1367
Query: 1032 IAEESQEGLCERESANGFETNVASGTCSIIVQERESR------EKGQKRPSDGNSGLMAK 1085
+ E +E L + + + + S+ ++E+++ E Q +P D +
Sbjct: 1368 LKEHIRETLAKIQESQSKQEQ------SLNMKEKDNETTKIVSEMEQFKPKDSALLRIEI 1421
Query: 1086 KQKRTPKRTSAAAKNEKNGTGQSSDSEDL-PVLDNSNELDNMNSTERISFLQEKLQEIRK 1144
+ KR + K+ + D + L VL + ++ N E ++ E +E++
Sbjct: 1422 EMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKV 1481
Query: 1145 YYMSLKSEVATIDRRRKRLKKKDREVS 1171
+ LK + TI+ R L +K+ E+S
Sbjct: 1482 AHCCLKEQEETINELRVNLSEKETEIS 1508
Score = 73.9 bits (180), Expect = 8e-13
Identities = 155/780 (19%), Positives = 317/780 (40%), Gaps = 102/780 (13%)
Query: 419 EEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVN 478
+EK +L++ +E + ++E T++K E I++ E ELK + + +A++ N
Sbjct: 1050 QEKNELQQMLESVIA-EKEQLKTDLKENIEMTIENQEELRLLGDELK--KQQEIVAQEKN 1106
Query: 479 -SIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQED 537
+IKKE E +T D+L + E K + + EK++ LL + + +KKI + E+
Sbjct: 1107 HAIKKEGELSRTCDRLAE--VEEKLKEKSQQLQEKQQQ--LLNVQEEMSEMQKKINEIEN 1162
Query: 538 SDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIK 597
+ +E + E + + E+ E+++ KV + QK +E
Sbjct: 1163 LKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKEL-----QKSFE---- 1213
Query: 598 STEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKR 657
TE D H G+ I ++ G + K++ K + E E
Sbjct: 1214 -TERD--------HLRGY-------------IREIEATGLQTKEELKIAHIHLKEHQETI 1251
Query: 658 DEERQKSKRGRPPLKSTLS-----SNMPYGLSKTANSEGKSDSCSSDSETEDAL-EKNLI 711
DE R+ + +T + + + + + SET++ + E L+
Sbjct: 1252 DELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELL 1311
Query: 712 NEELSLKDE-----LEKNENLNDDKLDEENPKISAHILKEND--RTQMQPLET----LKL 760
E+ + KD +E ++K E +I + + KE D +T + LE LK
Sbjct: 1312 TEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKS-LTKERDNLKTIKEALEVKHDQLKE 1370
Query: 761 EVGENEQIVQIFGNKMEKTEEVKKEAEKSPK--GKGRRSKTKDLSLEIIKISSFGQNEAG 818
+ E +Q +K E++ +K++ ++ K + + K KD +L I+I G ++
Sbjct: 1371 HIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRL 1430
Query: 819 SEPHIEAHSLELSSLDNKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGM--E 876
E H E S+ D + + E DQ ++ +K + E+++++ + E
Sbjct: 1431 QESHDEMKSVAKEKDDLQRLQEVLQSESDQL--KENIKEIVAKHLETEEELKVAHCCLKE 1488
Query: 877 MTNTVSQERTSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEE 936
T+++ R + + + + ++ E N+ + + I E + +Q ++ S +E
Sbjct: 1489 QEETINELRVN--LSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQI-SEVQE 1545
Query: 937 TVNIPLKEDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALP 996
VN +L E K +D A++S ES L L
Sbjct: 1546 KVN-----------------------ELKQFKEHRKA--KDSALQSIESKML-----ELT 1575
Query: 997 PVVQHNFSVASPLTLSQDESRSVKSESDITIEVDSIAEESQEGLCERESANGFETNVASG 1056
+Q + + ++E + V+ + IE D + E ++E + + + + E
Sbjct: 1576 NRLQESQEEIQIMIKEKEEMKRVQEA--LQIERDQLKENTKEIVAKMKESQEKEYQFLKM 1633
Query: 1057 TCSIIVQERESREKGQKRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSEDLPV 1116
T QE+ + K + + + + T +N + + + +DL
Sbjct: 1634 TAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRS 1693
Query: 1117 LDNSNELDN----MNSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSH 1172
++ + +++ N E I+ EK +E++ +M LK TID+ R + +K E+S+
Sbjct: 1694 VEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISN 1753
Score = 62.0 bits (149), Expect = 3e-09
Identities = 161/828 (19%), Positives = 332/828 (40%), Gaps = 111/828 (13%)
Query: 414 EPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDS----------NSESEREEI- 462
E K+KE+ + L+E ++ L + +EM + K EN+ + + E+ER E+
Sbjct: 1126 EEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELA 1185
Query: 463 --------ELKSPRGRRRIARDVNSIKKEIEEEK----------------TEDKLKDNDT 498
E+KS R++ ++ ++K E E+ T+++LK
Sbjct: 1186 QKLNENYEEVKSITKERKVLKE---LQKSFETERDHLRGYIREIEATGLQTKEELKIAHI 1242
Query: 499 ENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDKDSDEEE-----EKSQERE 553
K+ + + + +E NT ++ K QE+ +E+E ++ E +
Sbjct: 1243 HLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQ 1302
Query: 554 ETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYY 613
ET ++ + E+ L +++ K Q+ E IKS + + +
Sbjct: 1303 ETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQE-EIKSLTKERDNLKTIKE-- 1359
Query: 614 GWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKS 673
V++D+ + I L K ++ Q K+ ++ EKD + + + ++ +P +
Sbjct: 1360 ALEVKHDQ--LKEHIRETLAK--IQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSA 1415
Query: 674 TLSSNMP-YGLSK-TANSEGKSDSCSSDSETEDALEKNLINEELSLKDELEKNENLNDDK 731
L + GLSK S + S + + + L++ L +E LK+ ++ E +
Sbjct: 1416 LLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIK--EIVAKHL 1473
Query: 732 LDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTEEVKKEAEKSPK 791
EE K++ LKE + T + L++ + E E + ++E + + +
Sbjct: 1474 ETEEELKVAHCCLKEQEET----INELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIY 1529
Query: 792 GKGRRSKTKDLSLEIIKISSFGQ-NEAGSEPHIEAHSLELSSLDNKNFSSATEDEIDQCV 850
K + K +S K++ Q E S+E L+ N +++EI +
Sbjct: 1530 EKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMI 1589
Query: 851 KEKKLKRKILGQSSPEKKIRIENGMEMTNTV--SQERTSDCIGSEGM------------- 895
KEK+ +++ E+ EN E+ + SQE+ + +
Sbjct: 1590 KEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHL 1649
Query: 896 ------KNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFD-SPAEETVNIPLKEDEDA 948
+ LN E + E EN + ++ E+ + ++ +T ER D EET LK + D
Sbjct: 1650 KEQFETQKLNLE-NIETENIRLTQILHENLEEMRSVTKERDDLRSVEET----LKVERDQ 1704
Query: 949 MPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASP 1008
+ ET+ DL+++++ I + ++ + L +V + S
Sbjct: 1705 LKENLRETIT------RDLEKQEELKIVHMHLKEHQETI-----DKLRGIVSEKTNEISN 1753
Query: 1009 LTLSQDESRSVKSESDITIEVD-SIA----EESQEGLCERESANGFETNVASGTCSIIVQ 1063
+ + S D+ I+ + IA +E QE + + +T+ S +
Sbjct: 1754 MQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLEN 1813
Query: 1064 ER-ESREKGQKRPSDGNSGLMAKKQ-KRTPKRTSAAAKNEKNGTGQSSDSEDLPVLDNSN 1121
+ +EK Q+ ++ + + KK T K+ S + +K QS L
Sbjct: 1814 SNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKL------- 1866
Query: 1122 ELDNMNSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDRE 1169
E++N+N +++ E+++ + K +L+ T+ R +LK+ +E
Sbjct: 1867 EIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQE 1914
Score = 40.8 bits (94), Expect = 0.008
Identities = 39/147 (26%), Positives = 69/147 (46%), Gaps = 13/147 (8%)
Query: 417 VKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARD 476
V E +K + E ME+ K ++ LT K E E N++ + E+KS R R
Sbjct: 1839 VNETQKKVSE-MEQLKKQIKDQSLTLSKLEIE-NLNLAQKLHENLEEMKSVMKERDNLRR 1896
Query: 477 VNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKK-- 534
V K +E ++ ++ L++ + ++ + +TA E ++ K +EK +K
Sbjct: 1897 VEETLK-LERDQLKESLQETKARDLEIQQELKTARMLSKE---HKETVDKLREKISEKTI 1952
Query: 535 -----QEDSDKDSDEEEEKSQEREETE 556
Q+D DK DE ++K QE ++ E
Sbjct: 1953 QISDIQKDLDKSKDELQKKIQELQKKE 1979
Score = 35.4 bits (80), Expect = 0.33
Identities = 137/731 (18%), Positives = 274/731 (37%), Gaps = 89/731 (12%)
Query: 478 NSIKKEIEEEKTEDKLKDNDTENKDVDDDYET--AEKKENELLLGRKN-----------T 524
N K + +E E +L + ++ DYE EK+E EL L KN T
Sbjct: 485 NPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKT 544
Query: 525 PKQKEKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYG 584
K +E ++ + + K+ + E + E E E ++ED K++
Sbjct: 545 KKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIK-----KLQEYID 599
Query: 585 RGKTQKI-YEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKK 643
K + I + S I+D + + + V D K + + K+K K+
Sbjct: 600 SQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALD--AKRESAFLRSENLELKEKMKE 657
Query: 644 KAKNKEDSEKD-EKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSET 702
A + E D + + + K+ + L+ L S T+ +GK D
Sbjct: 658 LATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGK---VPKDLLC 714
Query: 703 EDALEKNLINEELSLKDELEKNENLNDD--------KLDEENPKISAHILKENDRTQMQP 754
LE + + + L E+E+NE L ++ L E ++ I +++ +
Sbjct: 715 NLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIIT 774
Query: 755 LETLKL--EVGENEQIVQIFGNKMEKTEE---VKKEAEKSPKGKGRRSKTKDLSLEIIKI 809
E KL EV E VQ ++ KT++ + KS + + KT + E
Sbjct: 775 SEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYK 834
Query: 810 SSFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDEID-QCVKEKKLKRKILGQSSPEKK 868
+NE ++ + S E D+ + TE Q ++EK + + + K
Sbjct: 835 MVLEENERMNQEIVNL-SKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLK 893
Query: 869 IRIENGMEMTNTVSQERTSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSE 928
++EN TV +E+T I + + L + +E + + L Q Q+ +
Sbjct: 894 EQLENRDSTLQTVEREKT--LITEKLQQTLEEVKTLTQEKDDLKQL-----QESLQIERD 946
Query: 929 RFDSPAEETVNIPLKEDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIE-DVAVESSESNS 987
+ S +TVN+ + E + E+L H+ ++ L K + ++ +E + +
Sbjct: 947 QLKSDIHDTVNMNIDTQEQLRNAL--ESLKQHQETINTLKSKISEEVSRNLHMEENTGET 1004
Query: 988 LVSIPPALPPV-VQHNFSVASPLTLSQDESRSVKSESDITI-----EVDSIAEESQEGLC 1041
+ + + + + TL+ D + E I E + + + + +
Sbjct: 1005 KDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIA 1064
Query: 1042 ERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNSGLMAKKQKRTPKRTSAAAKNE 1101
E+E +T++ I + E R G + + K+Q+ + + A K E
Sbjct: 1065 EKEQ---LKTDLKENIEMTIENQEELRLLGDE---------LKKQQEIVAQEKNHAIKKE 1112
Query: 1102 KNGTGQSSDSEDLPVLDNSNELDNMNSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRK 1161
G+ S + +R++ ++EKL+E + + ++ +
Sbjct: 1113 ----GELS-----------------RTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMS 1151
Query: 1162 RLKKKDREVSH 1172
++KK E+ +
Sbjct: 1152 EMQKKINEIEN 1162
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 75.1 bits (183), Expect = 4e-13
Identities = 161/842 (19%), Positives = 334/842 (39%), Gaps = 108/842 (12%)
Query: 416 KVKEEKKDLEESMEEALKLDQEMPLTEV--KSEPEENIDSNSESEREEIELKSPRGRRRI 473
K++ +++LEE E+ L QE+ E+ K +EN++ S++ + R
Sbjct: 259 KIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREK 318
Query: 474 ARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIK 533
A V+ ++ E+ K ++L D + V++ K++N++LL K + + + +
Sbjct: 319 AVRVDKLESEVSRYK--ERLHDIEFYKARVEE-----LKEDNQVLLETKTMLEDQLEGTR 371
Query: 534 KQEDSDKDSDEEEEKSQER-EETESKCDSEGEEDEEDMEPCLTGTKVKVKYGR------- 585
+ D + ++E + + + + E + D + ++ EE ME +T ++ K
Sbjct: 372 ARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMT-LEMAQKQSMDESLHLG 430
Query: 586 ------GKTQKIYEASIKST--EIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGP 637
+T ++ EA KS E+++ L+ N + V+ R +G
Sbjct: 431 WELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNA 490
Query: 638 KKKQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCS 697
K K + +N+ S+K E + E + K+ ++ LSK D
Sbjct: 491 SKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQN---------LSK--------DLMK 533
Query: 698 SDSETEDALEKNLINEELSLKDELEKNENLNDDKLD-EENPKISAH-----------ILK 745
++ E +E N E +K ++NE+LN + +ISA IL
Sbjct: 534 EKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILH 593
Query: 746 ENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTEEVKKEAEKSPK-GKGRRSKTKDLSL 804
E+ + L ++ E + ++ ++ + K E+ EE++ E K + + K +L +
Sbjct: 594 ESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKI 653
Query: 805 EIIKISSFGQNEAGSEPH-----------------IEAHSLELSSLDNKNFSSATEDEID 847
KI + Q + E +E+ E S LD +N E
Sbjct: 654 TCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESL 713
Query: 848 QCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNFEQHFERE 907
+C K + ++ + +K +++ G+E+ ++ + +G+ + E
Sbjct: 714 KCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGL---------DIE 764
Query: 908 NEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCHEVDLDDL 967
N+ + + SN+ IQQL SE D E N L+++ + + + L+ L
Sbjct: 765 NQRLQKTLENSNKKIQQLESELQDLEME---NQTLQKNLEELKISSKR--------LEQL 813
Query: 968 DEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESR--SVKSESDI 1025
++++K+ ++ + + L L + TL ++ + +++ E+
Sbjct: 814 EKENKSLEQETSQLEKDKKQLEKENKRLRQQAE-----IKDTTLEENNVKIGNLEKENKT 868
Query: 1026 TIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNSGLMAK 1085
+ I +ES L E E N A+ +V RE + + N+ L
Sbjct: 869 LSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDL--- 925
Query: 1086 KQKRTPKRTSAAAKNEKNGTGQSSDSEDLPVLDNSNELDNMNSTE----RISFLQEKLQE 1141
+K T + E+ + S + +L++ E S E +I+ L+ +L+E
Sbjct: 926 -EKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEE 984
Query: 1142 IRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAVE 1201
Y L+ E+ T+ + + LK++ E +S + D S + +L V+
Sbjct: 985 STNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVK 1044
Query: 1202 CR 1203
R
Sbjct: 1045 DR 1046
Score = 43.5 bits (101), Expect = 0.001
Identities = 102/483 (21%), Positives = 195/483 (40%), Gaps = 40/483 (8%)
Query: 704 DALEKNLINEELSLKDELEK-NENLNDD-KLDEENPKISAHILKENDRTQMQPLETLKLE 761
D + N + +++ K E ++ N+ +N+D L N I +K + +Q L + L
Sbjct: 44 DGVFLNQVMLQINPKLESQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLP 103
Query: 762 VGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEP 821
N I+ + TEEVKK G + + K+ +E I+ F +A
Sbjct: 104 ---NVLIIGKNPFSEQGTEEVKKLLLLL-LGCAVQCQKKEEFIERIQGLDF-DTKAAVAA 158
Query: 822 HIE--AHSLE-LSSLDNKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRI------E 872
HI+ H+ E + L + ++++I+ +K L K L E I
Sbjct: 159 HIQEVTHNQENVFDLQWMEVTDMSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEER 218
Query: 873 NGMEMTNTVSQERTSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDS 932
+G+ S S C GS GMK QH E + I Q +++ T + D
Sbjct: 219 DGLHFLPHASSSAQSPC-GSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDC 277
Query: 933 PAE-ETVNIPLK--EDEDAMPLIGPETLVCHEVDLDDLDEK----DKTSIEDVAVESSES 985
E E + I LK + E+ L + + +LD L EK DK E V+
Sbjct: 278 KQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESE-VSRYKERL 336
Query: 986 NSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVKSESDITIEVDSIAEESQEGLCERES 1045
+ + + + + N + T+ +D+ ++ SD E++ + + L + E
Sbjct: 337 HDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDME- 395
Query: 1046 ANGFETNVASGTCSIIVQERESREKGQKRPSDG--NSGLMAKKQKRTPKRTSAAAKNEKN 1103
E ++ +++E + E QK+ D + G ++ RT + + A K+ +
Sbjct: 396 ---MERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGH 452
Query: 1104 GTGQSSDSEDLPVLDNSNELDNMNSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKRL 1163
+ + S L + E++N + T+ + L+ + + S++ +++ +RL
Sbjct: 453 EVNELTSSRLLKL-----EMENQSLTKTVEELRTTVDSVE----GNASKILKMEKENQRL 503
Query: 1164 KKK 1166
KK
Sbjct: 504 SKK 506
Score = 33.9 bits (76), Expect = 0.96
Identities = 98/538 (18%), Positives = 192/538 (35%), Gaps = 66/538 (12%)
Query: 289 EEKEKEAKKTEEEVPEEELDPEERDNFLQQLYKFMEDRGTPI--NKPPVLGYKDLNLFKL 346
E+ EKE K E+E + E D ++ + ++L + E + T + N + + N
Sbjct: 811 EQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLS 870
Query: 347 FRLVYHQGGCDNI-----DSGAVWKQIYMDLG--IPILNSAASYNVKT-AYRKYLYGFEE 398
+ ++ C + ++ + K+ +D+ + + S +KT L
Sbjct: 871 KEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTH 930
Query: 399 YCRSANIQFRTVHHHEPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESE 458
+ + H E + K LE +E LK E+ ++ + +S + ++
Sbjct: 931 ELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQ 990
Query: 459 REEIELKSPRGRRRIARDVNSIKKEIEEEKTEDKL-----KDNDTENKDVDDDYETAEKK 513
+ ELK+ + ++ ++K+ +EE+ +DN E + + E + K
Sbjct: 991 QLRQELKT------VKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVK 1044
Query: 514 ENELLLGRKNTPKQKEKKIKKQEDSDKDSDEEEEKSQ-----------EREETESKCDSE 562
+ + + R N Q EK+ K + ++ ++Q + + T + +
Sbjct: 1045 DRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNA 1104
Query: 563 GEEDE----EDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE---------IDDGEVLYL 609
+ E L ++ + + E+ IK E I D E L L
Sbjct: 1105 KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLEL 1164
Query: 610 VHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKD-EKRDEERQKSKRGR 668
+H +A + K G K KN E +D E R + K K
Sbjct: 1165 LHER----------QASEYESLISKHGTLKSAH---KNLEVEHRDLEDRYNQLLKQKGQL 1211
Query: 669 PPLKSTLSSNMPYGLSKTANSEGKSDS----CSSDSETEDALEKNLINEELSLKDELEKN 724
L+ L L + N E + C + + L E+ D
Sbjct: 1212 EDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLK 1271
Query: 725 ENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTEEV 782
LN+ KL E ++ A K ++ Q + + KL + E + Q+ GN E+ +
Sbjct: 1272 SLLNNSKL--EQTRLEAEFSKLKEQYQQLDITSTKLN-NQCELLSQLKGNLEEENRHL 1326
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 74.7 bits (182), Expect = 5e-13
Identities = 163/843 (19%), Positives = 335/843 (39%), Gaps = 109/843 (12%)
Query: 416 KVKEEKKDLEESMEEALKLDQEMPLTEV--KSEPEENIDSNSESEREEIELKSPRGRRRI 473
K++ +++LEE E+ L QE+ E+ K +EN++ S++ + R
Sbjct: 259 KIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREK 318
Query: 474 ARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIK 533
A V+ ++ E+ K ++L D + V++ K++N++LL K + + + +
Sbjct: 319 AVRVDKLESEVSRYK--ERLHDIEFYKARVEE-----LKEDNQVLLETKTMLEDQLEGTR 371
Query: 534 KQEDSDKDSDEEEEKSQER-EETESKCDSEGEEDEEDMEPCLTGTKVKVKYGR------- 585
+ D + ++E + + + + E + D + ++ EE ME +T ++ K
Sbjct: 372 ARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMT-LEMAQKQSMDESLHLG 430
Query: 586 ------GKTQKIYEASIKST--EIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGP 637
+T ++ EA KS E+++ L+ N + V+ R +G
Sbjct: 431 WELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNA 490
Query: 638 KKKQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCS 697
K K + +N+ S+K E + E + K+ ++ LSK D
Sbjct: 491 SKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQN---------LSK--------DLMK 533
Query: 698 SDSETEDALEKNLINEELSLKDELEKNENLNDDKLD-EENPKISAH-----------ILK 745
++ E +E N E +K ++NE+LN + +ISA IL
Sbjct: 534 EKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILH 593
Query: 746 ENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTEEVKKEAEKSPK-GKGRRSKTKDLSL 804
E+ + L ++ E + ++ ++ + K E+ EE++ E K + + K +L +
Sbjct: 594 ESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKI 653
Query: 805 EIIKISSFGQNEAGSEPH-----------------IEAHSLELSSLDNKNFSSATEDEID 847
KI + Q + E +E+ E S LD +N E
Sbjct: 654 TCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESL 713
Query: 848 QCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNFEQHFERE 907
+C K + ++ + +K +++ G+E+ ++ + +G+ + E
Sbjct: 714 KCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGL---------DIE 764
Query: 908 NEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCHEVDLDDL 967
N+ + + SN+ IQQL SE D E N L+++ + + + L+ L
Sbjct: 765 NQRLQKTLENSNKKIQQLESELQDLEME---NQTLQKNLEELKISSKR--------LEQL 813
Query: 968 DEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESR--SVKSESDI 1025
++++K+ ++ + + L L + TL ++ + +++ E+
Sbjct: 814 EKENKSLEQETSQLEKDKKQLEKENKRLRQQAE-----IKDTTLEENNVKIGNLEKENKT 868
Query: 1026 TIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNSGLMAK 1085
+ I +ES L E E N A+ +V RE + + N+ L
Sbjct: 869 LSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDL--- 925
Query: 1086 KQKRTPKRTSAAAKNEKN-GTGQSSDSEDLPVLDNSNELDNMNSTE----RISFLQEKLQ 1140
+K T + E+ QS+D +L++ E S E +I+ L+ +L+
Sbjct: 926 -EKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLE 984
Query: 1141 EIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAV 1200
E Y L+ E+ T+ + + LK++ E +S + D S + +L V
Sbjct: 985 ESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKV 1044
Query: 1201 ECR 1203
+ R
Sbjct: 1045 KDR 1047
Score = 43.5 bits (101), Expect = 0.001
Identities = 102/483 (21%), Positives = 195/483 (40%), Gaps = 40/483 (8%)
Query: 704 DALEKNLINEELSLKDELEK-NENLNDD-KLDEENPKISAHILKENDRTQMQPLETLKLE 761
D + N + +++ K E ++ N+ +N+D L N I +K + +Q L + L
Sbjct: 44 DGVFLNQVMLQINPKLESQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLP 103
Query: 762 VGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEP 821
N I+ + TEEVKK G + + K+ +E I+ F +A
Sbjct: 104 ---NVLIIGKNPFSEQGTEEVKKLLLLL-LGCAVQCQKKEEFIERIQGLDF-DTKAAVAA 158
Query: 822 HIE--AHSLE-LSSLDNKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRI------E 872
HI+ H+ E + L + ++++I+ +K L K L E I
Sbjct: 159 HIQEVTHNQENVFDLQWMEVTDMSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEER 218
Query: 873 NGMEMTNTVSQERTSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDS 932
+G+ S S C GS GMK QH E + I Q +++ T + D
Sbjct: 219 DGLHFLPHASSSAQSPC-GSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDC 277
Query: 933 PAE-ETVNIPLK--EDEDAMPLIGPETLVCHEVDLDDLDEK----DKTSIEDVAVESSES 985
E E + I LK + E+ L + + +LD L EK DK E V+
Sbjct: 278 KQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESE-VSRYKERL 336
Query: 986 NSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVKSESDITIEVDSIAEESQEGLCERES 1045
+ + + + + N + T+ +D+ ++ SD E++ + + L + E
Sbjct: 337 HDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDME- 395
Query: 1046 ANGFETNVASGTCSIIVQERESREKGQKRPSDG--NSGLMAKKQKRTPKRTSAAAKNEKN 1103
E ++ +++E + E QK+ D + G ++ RT + + A K+ +
Sbjct: 396 ---MERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGH 452
Query: 1104 GTGQSSDSEDLPVLDNSNELDNMNSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKRL 1163
+ + S L + E++N + T+ + L+ + + S++ +++ +RL
Sbjct: 453 EVNELTSSRLLKL-----EMENQSLTKTVEELRTTVDSVE----GNASKILKMEKENQRL 503
Query: 1164 KKK 1166
KK
Sbjct: 504 SKK 506
Score = 32.0 bits (71), Expect = 3.6
Identities = 77/409 (18%), Positives = 144/409 (35%), Gaps = 56/409 (13%)
Query: 408 RTVHHHEPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSP 467
R +H + K LE +E LK E+ ++ + +S + +++ ELK+
Sbjct: 941 RLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKT- 999
Query: 468 RGRRRIARDVNSIKKEIEEEKTEDKL-----KDNDTENKDVDDDYETAEKKENELLLGRK 522
+ ++ ++K+ +EE+ +DN E + + E + K+ + + R
Sbjct: 1000 -----VKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERN 1054
Query: 523 NTPKQKEKKIKKQEDSDKDSDEEEEKSQ-----------EREETESKCDSEGEEDE---- 567
N Q EK+ K + ++ ++Q + + T + + + E
Sbjct: 1055 NATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1114
Query: 568 EDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE---------IDDGEVLYLVHYYGWNVR 618
L ++ + + E+ IK E I D E L L+H
Sbjct: 1115 NSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHER----- 1169
Query: 619 YDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKD-EKRDEERQKSKRGRPPLKSTLSS 677
+A + K G K KN E +D E R + K K L+ L
Sbjct: 1170 -----QASEYESLISKHGTLKSAH---KNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKV 1221
Query: 678 NMPYGLSKTANSEGKSDS----CSSDSETEDALEKNLINEELSLKDELEKNENLNDDKLD 733
L + N E + C + + L E+ D LN+ KL
Sbjct: 1222 EQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKL- 1280
Query: 734 EENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTEEV 782
E ++ A K ++ Q + + KL + E + Q+ GN E+ +
Sbjct: 1281 -EQTRLEAEFSKLKEQYQQLDITSTKLN-NQCELLSQLKGNLEEENRHL 1327
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 71.6 bits (174), Expect = 4e-12
Identities = 110/452 (24%), Positives = 188/452 (41%), Gaps = 63/452 (13%)
Query: 415 PKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIA 474
PK+K + K +EE +EE K++ E KSE EE + + +E +A
Sbjct: 444 PKLKVQHKFVEEIIEET-KVEDE------KSEMEEALTAITE---------------ELA 481
Query: 475 RDVNSIKKEIEEEKTED-KLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIK 533
+ KKE EEK E+ + ++ + K E KE E G K + +E+ +
Sbjct: 482 VSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEE---GEKEEEEGQEE--E 536
Query: 534 KQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYE 593
++ED SD+ EE E+E + K EGE++E + E G + + K + +K E
Sbjct: 537 EEEDEGAKSDQAEEGGSEKEGSSEK--EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEE 594
Query: 594 ASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEK 653
+ K + D + V E K+ P+++ G K + K S
Sbjct: 595 VATKEELVADAK-----------VEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 643
Query: 654 DEKRDEERQKS--------KRGRPPL-KSTLSSNMPYGLSKTANSEGKSDSCSSDSETED 704
+ EE+ KS ++G+ P+ KS + + K+ E KS + E ++
Sbjct: 644 PKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKE 703
Query: 705 ALEKNLINEELSLKDELEKNENLNDD---KLDEENPKISAHILKENDRTQMQPLETLKLE 761
EK + +E ++++EK E D K E+P + + T+ + L+ E
Sbjct: 704 EEEKEV--KEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVH-LEKE 760
Query: 762 VGENEQIVQIFGNKMEKTEEVKKEAEKSPKG-KGRRSKTKDLSLEIIKISSFGQ--NEAG 818
E + +Q K + E E E S KG KG R + ++ E+ Q E G
Sbjct: 761 TKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKG 820
Query: 819 S----EPHIEAHSLELSSLDNKNFSSATEDEI 846
S E + + L+LS D K +E+++
Sbjct: 821 SGREEEKGVVTNGLDLSPADEKKGGDKSEEKV 852
Score = 53.5 bits (127), Expect = 1e-06
Identities = 79/409 (19%), Positives = 162/409 (39%), Gaps = 69/409 (16%)
Query: 414 EPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRI 473
E K E+K+ E EE ++ P+ E +E E E +E E + G +
Sbjct: 487 EKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSD 546
Query: 474 ARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQ--KEKK 531
+ +KE EK E + ++ +TE + ++ E E+K+ E T ++ + K
Sbjct: 547 QAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAK 606
Query: 532 IKKQEDS----DKDSDEEEEKS-------QEREETESKCDSEGEEDEEDMEPCLTGTKVK 580
++K E + K EE+ KS +E+ ++ E+ + + K K
Sbjct: 607 VEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGK 666
Query: 581 VKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKK 640
+ ++ ++ + + +++ + KA+ + KG K++
Sbjct: 667 SPVSKSPVEEKAKSPVPKSPVEEAK-----------------SKAE-----VGKGEQKEE 704
Query: 641 QKKKAKNKEDSEKDEKRDEERQ---KSKRGRPPLKS-------TLSSNMPYGLSKTANSE 690
++K+ K EK EK++E+ + + K+ P+K T++ ++ L K E
Sbjct: 705 EEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEE 764
Query: 691 GK-----------SDSCSSDSETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKI 739
GK S+ E D K E++++ E+E E + + +
Sbjct: 765 GKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKE------ 818
Query: 740 SAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTEEVKKEAEK 788
K + R + + + T L++ ++ + G+K E+ V K EK
Sbjct: 819 -----KGSGREEEKGVVTNGLDLSPADE--KKGGDKSEEKVVVTKTVEK 860
Score = 52.8 bits (125), Expect = 2e-06
Identities = 89/430 (20%), Positives = 173/430 (40%), Gaps = 48/430 (11%)
Query: 473 IARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKI 532
I+ + K E + K + K + E V+D E +E +E + + KE+K
Sbjct: 432 ISSKIQKPKVEAPKLKVQHKFVEEIIEETKVED--EKSEMEEALTAITEELAVSMKEEKK 489
Query: 533 KKQEDSDKDSDEEEEK------------SQEREETESKCDSEGEEDEEDMEPCLTGTKVK 580
+ E+ +++ + EEE+ + +EE K + EG+E+EE+ + + +
Sbjct: 490 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE 549
Query: 581 ----VKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGG 636
K G + ++ + ++ +GE + +E + ++
Sbjct: 550 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK 609
Query: 637 PKKKQ----KKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGK 692
P+K + K + K S + EE+ KS + P++ S +P +GK
Sbjct: 610 PEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVP---KSPVEEKGK 666
Query: 693 SDSCSS--DSETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRT 750
S S + + + + K+ + EE K E+ K E +++ + + + K+ ++
Sbjct: 667 SPVSKSPVEEKAKSPVPKSPV-EEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKP 725
Query: 751 QMQPLETLKLEVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKIS 810
+ P E K E E+ V + T+ VK EK K +G K L E K
Sbjct: 726 KDVP-EKKKAESPVKEEAV---AEVVTITKSVKVHLEKETKEEG-----KPLQQEKEKEK 776
Query: 811 SFGQNEAGSEPHIEAHSLELSSLDNKNFSSATE--DEIDQCVKEKKLKRKILGQSSPEKK 868
+ G E GSE + S ++ + E +E++Q KEK G E+K
Sbjct: 777 AGG--EGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEK-------GSGREEEK 827
Query: 869 IRIENGMEMT 878
+ NG++++
Sbjct: 828 GVVTNGLDLS 837
Score = 31.6 bits (70), Expect = 4.8
Identities = 40/165 (24%), Positives = 74/165 (44%), Gaps = 12/165 (7%)
Query: 151 TEDEKEEESSEEEDEDKRRLNDELLGKVVSVVSATERTEWYPALVISPSCNDDITVKKDQ 210
TE E E E +E ++E K E + +V+ + + P SP + K
Sbjct: 571 TEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK--PEKAKSPVPKSPVEEKGKS 628
Query: 211 CLVRSFIDSKFYS-IARKDIKEVDILNLPESELSTKPGLQKASIFLKTRVVPDNWKMDIS 269
+ +S ++ K S + + ++E +P+S P +K + V + K +
Sbjct: 629 PVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS-----PVEEKGKSPVSKSPVEEKAKSPVP 683
Query: 270 EI-LESSSSDDEDGPAEENDEEKEKEAKKT--EEEVPEEELDPEE 311
+ +E + S E G E+ +EE EKE K+ EE+V ++E P++
Sbjct: 684 KSPVEEAKSKAEVGKGEQKEEE-EKEVKEAPKEEKVEKKEEKPKD 727
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 71.6 bits (174), Expect = 4e-12
Identities = 110/452 (24%), Positives = 188/452 (41%), Gaps = 63/452 (13%)
Query: 415 PKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIA 474
PK+K + K +EE +EE K++ E KSE EE + + +E +A
Sbjct: 68 PKLKVQHKFVEEIIEET-KVEDE------KSEMEEALTAITE---------------ELA 105
Query: 475 RDVNSIKKEIEEEKTED-KLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIK 533
+ KKE EEK E+ + ++ + K E KE E G K + +E+ +
Sbjct: 106 VSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEE---GEKEEEEGQEE--E 160
Query: 534 KQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYE 593
++ED SD+ EE E+E + K EGE++E + E G + + K + +K E
Sbjct: 161 EEEDEGAKSDQAEEGGSEKEGSSEK--EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEE 218
Query: 594 ASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEK 653
+ K + D + V E K+ P+++ G K + K S
Sbjct: 219 VATKEELVADAK-----------VEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 267
Query: 654 DEKRDEERQKS--------KRGRPPL-KSTLSSNMPYGLSKTANSEGKSDSCSSDSETED 704
+ EE+ KS ++G+ P+ KS + + K+ E KS + E ++
Sbjct: 268 PKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKE 327
Query: 705 ALEKNLINEELSLKDELEKNENLNDD---KLDEENPKISAHILKENDRTQMQPLETLKLE 761
EK + +E ++++EK E D K E+P + + T+ + L+ E
Sbjct: 328 EEEKEV--KEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVH-LEKE 384
Query: 762 VGENEQIVQIFGNKMEKTEEVKKEAEKSPKG-KGRRSKTKDLSLEIIKISSFGQ--NEAG 818
E + +Q K + E E E S KG KG R + ++ E+ Q E G
Sbjct: 385 TKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKG 444
Query: 819 S----EPHIEAHSLELSSLDNKNFSSATEDEI 846
S E + + L+LS D K +E+++
Sbjct: 445 SGREEEKGVVTNGLDLSPADEKKGGDKSEEKV 476
Score = 53.5 bits (127), Expect = 1e-06
Identities = 79/409 (19%), Positives = 162/409 (39%), Gaps = 69/409 (16%)
Query: 414 EPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRI 473
E K E+K+ E EE ++ P+ E +E E E +E E + G +
Sbjct: 111 EKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSD 170
Query: 474 ARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQ--KEKK 531
+ +KE EK E + ++ +TE + ++ E E+K+ E T ++ + K
Sbjct: 171 QAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAK 230
Query: 532 IKKQEDS----DKDSDEEEEKS-------QEREETESKCDSEGEEDEEDMEPCLTGTKVK 580
++K E + K EE+ KS +E+ ++ E+ + + K K
Sbjct: 231 VEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGK 290
Query: 581 VKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKK 640
+ ++ ++ + + +++ + KA+ + KG K++
Sbjct: 291 SPVSKSPVEEKAKSPVPKSPVEEAK-----------------SKAE-----VGKGEQKEE 328
Query: 641 QKKKAKNKEDSEKDEKRDEERQ---KSKRGRPPLKS-------TLSSNMPYGLSKTANSE 690
++K+ K EK EK++E+ + + K+ P+K T++ ++ L K E
Sbjct: 329 EEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEE 388
Query: 691 GK-----------SDSCSSDSETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKI 739
GK S+ E D K E++++ E+E E + + +
Sbjct: 389 GKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKE------ 442
Query: 740 SAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTEEVKKEAEK 788
K + R + + + T L++ ++ + G+K E+ V K EK
Sbjct: 443 -----KGSGREEEKGVVTNGLDLSPADE--KKGGDKSEEKVVVTKTVEK 484
Score = 52.8 bits (125), Expect = 2e-06
Identities = 89/430 (20%), Positives = 173/430 (40%), Gaps = 48/430 (11%)
Query: 473 IARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKI 532
I+ + K E + K + K + E V+D E +E +E + + KE+K
Sbjct: 56 ISSKIQKPKVEAPKLKVQHKFVEEIIEETKVED--EKSEMEEALTAITEELAVSMKEEKK 113
Query: 533 KKQEDSDKDSDEEEEK------------SQEREETESKCDSEGEEDEEDMEPCLTGTKVK 580
+ E+ +++ + EEE+ + +EE K + EG+E+EE+ + + +
Sbjct: 114 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE 173
Query: 581 ----VKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGG 636
K G + ++ + ++ +GE + +E + ++
Sbjct: 174 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK 233
Query: 637 PKKKQ----KKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGK 692
P+K + K + K S + EE+ KS + P++ S +P +GK
Sbjct: 234 PEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVP---KSPVEEKGK 290
Query: 693 SDSCSS--DSETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRT 750
S S + + + + K+ + EE K E+ K E +++ + + + K+ ++
Sbjct: 291 SPVSKSPVEEKAKSPVPKSPV-EEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKP 349
Query: 751 QMQPLETLKLEVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKIS 810
+ P E K E E+ V + T+ VK EK K +G K L E K
Sbjct: 350 KDVP-EKKKAESPVKEEAV---AEVVTITKSVKVHLEKETKEEG-----KPLQQEKEKEK 400
Query: 811 SFGQNEAGSEPHIEAHSLELSSLDNKNFSSATE--DEIDQCVKEKKLKRKILGQSSPEKK 868
+ G E GSE + S ++ + E +E++Q KEK G E+K
Sbjct: 401 AGG--EGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEK-------GSGREEEK 451
Query: 869 IRIENGMEMT 878
+ NG++++
Sbjct: 452 GVVTNGLDLS 461
Score = 31.6 bits (70), Expect = 4.8
Identities = 40/165 (24%), Positives = 74/165 (44%), Gaps = 12/165 (7%)
Query: 151 TEDEKEEESSEEEDEDKRRLNDELLGKVVSVVSATERTEWYPALVISPSCNDDITVKKDQ 210
TE E E E +E ++E K E + +V+ + + P SP + K
Sbjct: 195 TEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK--PEKAKSPVPKSPVEEKGKS 252
Query: 211 CLVRSFIDSKFYS-IARKDIKEVDILNLPESELSTKPGLQKASIFLKTRVVPDNWKMDIS 269
+ +S ++ K S + + ++E +P+S P +K + V + K +
Sbjct: 253 PVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS-----PVEEKGKSPVSKSPVEEKAKSPVP 307
Query: 270 EI-LESSSSDDEDGPAEENDEEKEKEAKKT--EEEVPEEELDPEE 311
+ +E + S E G E+ +EE EKE K+ EE+V ++E P++
Sbjct: 308 KSPVEEAKSKAEVGKGEQKEEE-EKEVKEAPKEEKVEKKEEKPKD 351
>gi|47078224 AT rich interactive domain 5A [Homo sapiens]
Length = 594
Score = 71.2 bits (173), Expect = 5e-12
Identities = 51/204 (25%), Positives = 92/204 (45%), Gaps = 26/204 (12%)
Query: 273 ESSSSDDEDGPAEENDEEKEKEAKK--TEEEVPE------EELDPEERDNFLQQLYKFME 324
+S+ D D PA K+ + + E+ PE EE + EE FL LYKFM+
Sbjct: 11 QSTEGDALDPPASPKPAGKQNGIQNPISLEDSPEAGGEREEEQEREEEQAFLVSLYKFMK 70
Query: 325 DRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNIDSGAVWKQIYMDLGIPILNSAASYN 384
+R TPI + P LG+K +NL+K+++ V G + + +WK +Y +LG +++A+
Sbjct: 71 ERHTPIERVPHLGFKQINLWKIYKAVEKLGAYELVTGRRLWKNVYDELGGSPGSTSAATC 130
Query: 385 VKTAYRKYLYGFEEYCRSAN----------IQFRTVHHH--------EPKVKEEKKDLEE 426
+ Y + + + + + + Q++ + PK +E++ +++
Sbjct: 131 TRRHYERLVLPYVRHLKGEDDKPLPTSKPRKQYKMAKENRGDDGATERPKKAKEERRMDQ 190
Query: 427 SMEEALKLDQEMPLTEVKSEPEEN 450
M K D P EP N
Sbjct: 191 MMPGKTKADAADPAPLPSQEPPRN 214
>gi|56676335 RAP1 interacting factor 1 [Homo sapiens]
Length = 2472
Score = 70.9 bits (172), Expect = 7e-12
Identities = 154/754 (20%), Positives = 281/754 (37%), Gaps = 110/754 (14%)
Query: 419 EEKKDLEESMEEALKLDQEMP----LTEVKSEPEENIDSNSESEREEIELKSPRGRRRIA 474
E +K+ EES+E + L+ P TE S+ + ++ S S E + +LK+ +
Sbjct: 1309 EPEKNTEESVEGIVVLENNPPGLLNQTECVSDNQVHL-SESTMEHDNTKLKAATVENAVL 1367
Query: 475 RDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKK 534
+ N+++++ E E K +T + D E + ++ +K + ++ +
Sbjct: 1368 LETNTVEEKNVEINLESK---ENTPPVVISADQMVNEDSQVQITPNQKTLRRSSRRRSEV 1424
Query: 535 QEDSDKDSDEEE--EKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIY 592
E + + D+E +K + R+E E ++D+ P K + I
Sbjct: 1425 VESTTESQDKENSHQKKERRKEEEKPLQKSPLHIKDDVLP--------------KQKLIA 1470
Query: 593 EASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKA-----KN 647
E +++ I+ G L+ ++ + ++ KKKA K+
Sbjct: 1471 EQTLQENLIEKGSNLH-----------------EKTLGETSANAETEQNKKKADPENIKS 1513
Query: 648 KEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDS--ETEDA 705
+ D +D D+ +K RGR ++ +S LS NSE S + +
Sbjct: 1514 EGDGTQDIV-DKSSEKLVRGRTRYQTRRASQGL--LSSIENSESDSSEAKEEGSRKKRSG 1570
Query: 706 LEKNLINEELSLKDELEK----------NENLNDDKLDEENPKISAHILKENDRTQMQPL 755
KN NE + ++D+ EK N++ + EE+ I + I ++ D +
Sbjct: 1571 KWKNKSNESVDIQDQEEKVVKQECIKAENQSHDYKATSEEDVSIKSPICEKQDESNTVIC 1630
Query: 756 ETLKLEVGENEQIVQIFGNKMEKTEEVKKEAEKS------PKGKGRRSKTKDLSLEIIKI 809
+ + + Q+ N E+ E K AE S P+ R T++ + K
Sbjct: 1631 QDSTV-TSDLLQVPDDLPNVCEEKNETSKYAEYSFTSLPVPESNLR---TRNAIKRLHKR 1686
Query: 810 SSFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKI 869
SF G I ++SSL K F + +C Q +++
Sbjct: 1687 DSFDNCSLGESSKIGIS--DISSLSEKTFQTL------EC------------QHKRSRRV 1726
Query: 870 RIENGMEMTNTVSQERTSDCIGSEGMKNLNFE-QHFERENEGMPSLIAESNQCIQQLTSE 928
R G + SQ + IG + +N + E ++ + P +E++Q +
Sbjct: 1727 RRSKGCDCCGEKSQPQEKSLIGLKNTENNDVEISETKKADVQAPVSPSETSQANPYSEGQ 1786
Query: 929 RFDSPAEETVNIPLKEDEDAM--PLIGPETLVCHEVDLDDLDEKDKTSIEDVA-VESSES 985
D ++ LKED D + LI ET + L E++ ++SSE+
Sbjct: 1787 FLDEHHSVNFHLGLKEDNDTINDSLIVSETKSKENTMQESLPSGIVNFREEICDMDSSEA 1846
Query: 986 NSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVKSESDITIEVDSIAEESQEGLCERES 1045
SL S NF P +S++V ES T E E E +
Sbjct: 1847 MSLES-----QESPNENFKTVGPCL---GDSKNVSQESLETKEEKPEETPKMELSLENVT 1898
Query: 1046 ANG-----FETNVASGTCSIIVQERESREKGQKRPSDGNSGLMA-KKQKRTPKRTSAAAK 1099
G E+N+ + E+ GQ+R G S A ++ KR + AK
Sbjct: 1899 VEGNACKVTESNLEKAKTMELNVGNEASFHGQERTKTGISEEAAIEENKRNDDSEADTAK 1958
Query: 1100 NEKNGTGQSSDSEDLPVLDNSNELDNMNSTERIS 1133
+ D+ + DN+ + +N+ IS
Sbjct: 1959 LNAKEVATEEFNSDISLSDNTTPV-KLNAQTEIS 1991
Score = 41.2 bits (95), Expect = 0.006
Identities = 144/698 (20%), Positives = 270/698 (38%), Gaps = 102/698 (14%)
Query: 481 KKEIEEEK---TEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQED 537
+K E+ K TE+++ + +DV +D AE E L + K E
Sbjct: 1110 RKPKEDSKMMITEEQMDSDIVIPQDVTEDCGMAEHLEKSSLSNNECGSLDKTSP----EM 1165
Query: 538 SDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVK--VKYGRGKTQKIYEAS 595
S+ ++DE ++ +T ++C S E ++ T V Y + Q
Sbjct: 1166 SNSNNDERKKALISSRKTSTECASSTENSFVVSSSSVSNTTVAGTPPYPTSRRQTF---- 1221
Query: 596 IKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEK-- 653
I + D E N+ VK ++ PK KQ++ +K DSEK
Sbjct: 1222 ITLEKFDGSENRPFSPSPLNNISSTVTVKNNQETMIKTDFLPKAKQREGTFSKSDSEKIV 1281
Query: 654 -DEKRDE------ERQKSKRGRPPLKS--------------TLSSNMPYGLSKTA----N 688
KR E+ +KR +P ++S L +N P L++T N
Sbjct: 1282 NGTKRSSRRAGKAEQTGNKRSKPLMRSEPEKNTEESVEGIVVLENNPPGLLNQTECVSDN 1341
Query: 689 SEGKSDSCSSDSET-------EDA--LEKNLINEELSLKDELEKNEN-----LNDDKLDE 734
S+S T E+A LE N + EE +++ LE EN ++ D++
Sbjct: 1342 QVHLSESTMEHDNTKLKAATVENAVLLETNTV-EEKNVEINLESKENTPPVVISADQMVN 1400
Query: 735 ENPKI----SAHILKENDRTQMQPLE-TLKLEVGENEQIVQIFGNKMEKTEEVKKEAEKS 789
E+ ++ + L+ + R + + +E T + + EN K E+ +E +K +KS
Sbjct: 1401 EDSQVQITPNQKTLRRSSRRRSEVVESTTESQDKENSH------QKKERRKEEEKPLQKS 1454
Query: 790 ---------PKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSS 840
PK K +T +L I K S+ + G D +N S
Sbjct: 1455 PLHIKDDVLPKQKLIAEQTLQENL-IEKGSNLHEKTLGETSANAETEQNKKKADPENIKS 1513
Query: 841 ATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF 900
E + Q + +K ++ + G++ + + R G+ +++ + E S EG +
Sbjct: 1514 --EGDGTQDIVDKSSEKLVRGRTRYQTR-RASQGL-LSSIENSESDSSEAKEEGSRKKRS 1569
Query: 901 EQHFERENEGMPSLIAE----SNQCIQ-QLTSERFDSPAEETVNI--PLKEDEDAMPLIG 953
+ + NE + E +CI+ + S + + +EE V+I P+ E +D
Sbjct: 1570 GKWKNKSNESVDIQDQEEKVVKQECIKAENQSHDYKATSEEDVSIKSPICEKQDE----- 1624
Query: 954 PETLVCHE--VDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPL-- 1009
T++C + V D L D + +V E +E++ PV + N + +
Sbjct: 1625 SNTVICQDSTVTSDLLQVPD--DLPNVCEEKNETSKYAEYSFTSLPVPESNLRTRNAIKR 1682
Query: 1010 --TLSQDESRSVKSESDITI-EVDSIAEESQEGL-CERESANGFETNVASGTCSIIVQER 1065
++ S+ S I I ++ S++E++ + L C+ + + + C Q +
Sbjct: 1683 LHKRDSFDNCSLGESSKIGISDISSLSEKTFQTLECQHKRSRRVRRSKGCDCCGEKSQPQ 1742
Query: 1066 ESREKGQKRPSDGNSGLMAKKQKRTPKRTSAAAKNEKN 1103
E G K + + + K+ S + ++ N
Sbjct: 1743 EKSLIGLKNTENNDVEISETKKADVQAPVSPSETSQAN 1780
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 70.5 bits (171), Expect = 9e-12
Identities = 88/380 (23%), Positives = 153/380 (40%), Gaps = 56/380 (14%)
Query: 416 KVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIAR 475
K ++ K LEE + K QE+ K E + E ER E E + R R R
Sbjct: 283 KFRDTHKKLEEEKGKKEKERQEIE----KERRERERERERERERRERERERERERER--- 335
Query: 476 DVNSIKKEIEEEKTEDKLKDND-TENKDVDDDYETAEKKENELLLGR-KNTPKQKEKKIK 533
+KE E E+ ++ +D D T+ +D D D E ++ E R K+ + +EK
Sbjct: 336 -----EKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRD 390
Query: 534 KQEDSDKDSDEEEEKSQERE-ETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIY 592
++ + +++ + E E+ +ERE E E + + E E + E K K + + Y
Sbjct: 391 RERERERERERERERERERERERERERERERERERE---------KDKKRDREEDEEDAY 441
Query: 593 EASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSE 652
E ++ + E Y W +R +++K + KE
Sbjct: 442 ERRKLERKLREKEAAYQERLKNWEIR--------------------ERKKTREYEKEAER 481
Query: 653 KDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLIN 712
++E+R E +++KR LK L + K S+ + EK +
Sbjct: 482 EEERRREMAKEAKR----LKEFLED------YDDDRDDPKYYRGSALQKRLRDREKEMEA 531
Query: 713 EELSLKDELEKNENLNDDKLDEENPKISAHI--LKENDRTQMQPLETLKLEVGENEQIVQ 770
+E K E E+ E + L E +P A + +++ + QP + E E E+ Q
Sbjct: 532 DERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQ 591
Query: 771 IFGNKMEKTEEVKKEAEKSP 790
K E+ E ++E E+ P
Sbjct: 592 EKEEKREEPMEEEEEPEQKP 611
Score = 52.8 bits (125), Expect = 2e-06
Identities = 47/192 (24%), Positives = 91/192 (47%), Gaps = 34/192 (17%)
Query: 418 KEEKKDLEESMEEALKLDQ-EMPLTEVKSEPEENIDSNSESERE---EIELKSPRG---R 470
K++K+D EE E+A + + E L E ++ +E + + ER+ E E ++ R R
Sbjct: 427 KDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERR 486
Query: 471 RRIARDVNSIKKEIEE-----------------EKTEDKLKDNDTENKDVDDDYETAEKK 513
R +A++ +K+ +E+ ++ D+ K+ + + +D + E E+
Sbjct: 487 REMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEI 546
Query: 514 ENELLLGRKNTP--------KQKEKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEE 565
LL P ++ E++ + Q + +S+EEEE+ QE+EE + EE
Sbjct: 547 RQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKRE--EPMEEE 604
Query: 566 DEEDMEPCLTGT 577
+E + +PCL T
Sbjct: 605 EEPEQKPCLKPT 616
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 69.7 bits (169), Expect = 2e-11
Identities = 97/426 (22%), Positives = 186/426 (43%), Gaps = 62/426 (14%)
Query: 414 EPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRI 473
E +++E++K+L E +E + + E E EE + E RE+ E K R R+
Sbjct: 320 EKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEE-KMWRQEERL 378
Query: 474 ARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDY-ETAEKKENELLLGRKNTPKQKEKKI 532
+K++ E+ E K++D + + D+ E E+ + + + ++EKK+
Sbjct: 379 WEQ----EKQMREQ--EQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKM 432
Query: 533 KKQEDSDKDSDE---EEEKSQERE-----------ETESKCDSEGE-----EDEEDMEPC 573
++QE +D +E EEE+ +ERE E E K + E E++E +
Sbjct: 433 QEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 492
Query: 574 LTGTKVKV---KYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGW---NVRYDE---WVK 624
L K K+ + + + +KI+E + +I D E ++ W +R E W +
Sbjct: 493 LPEQKEKLWEQEKMQEQEEKIWE---QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 549
Query: 625 ADRI------IWPLDKGGPKK--KQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLS 676
+++ +W ++ KK +Q+KK ++E+ ++E+R ER+K R +
Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 609
Query: 677 SNMPYGLSKTANSEGK----SDSCSSDSETEDALEKNLINEELSL---------KDELEK 723
M K E K + E E+ + +E + K++L +
Sbjct: 610 EKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE 669
Query: 724 NENLND-DKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTEEV 782
+E + + +K+ E+ KI K +TQ Q +T E E+ ++ KM + EE+
Sbjct: 670 HEKMQEQEKMQEQEEKIWEQ-EKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM 728
Query: 783 KKEAEK 788
+E E+
Sbjct: 729 MREQEE 734
Score = 55.5 bits (132), Expect = 3e-07
Identities = 61/269 (22%), Positives = 118/269 (43%), Gaps = 44/269 (16%)
Query: 406 QFRTVHHHEPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELK 465
Q R E + EK +E M+E + E E K++ +E + E REE +
Sbjct: 657 QQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREE---E 713
Query: 466 SPRGRRRIARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEK--KENELLLGRKN 523
S R R + R+ + +E EE+ E + K + E ++ +E EK ++ E + ++
Sbjct: 714 SMREREKKMREEEEMMREQEEKMQEQEEKMQEQE----EEMWEQEEKMWEQEEKMWEQQR 769
Query: 524 TPKQKEKKIKKQEDSDKDSD-EEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVK 582
P+QKEK + ++ +++ E+EEK +++EE + + EE M
Sbjct: 770 LPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKM------------ 817
Query: 583 YGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQK 642
RG+ +K++ K W W + ++ +W ++ +K Q
Sbjct: 818 --RGQEEKMWGQEEKM----------------WGQEEKMWGQEEK-MWGQEEKMEEKMQG 858
Query: 643 KKAKNKEDSEK---DEKRDEERQKSKRGR 668
++ K +E EK E++ E+++ RG+
Sbjct: 859 QEEKMREQEEKMRGQEEKMREQEEKMRGQ 887
Score = 53.5 bits (127), Expect = 1e-06
Identities = 90/480 (18%), Positives = 207/480 (43%), Gaps = 45/480 (9%)
Query: 424 LEESM----EEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNS 479
L+E M EE + ++++ E K +E E + E E K R +R+
Sbjct: 270 LQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKE 329
Query: 480 IKKEIEEEKTEDKLKDNDTENKDVDD---DYETAEKKENELLLGRKNTPKQKEKKIKKQE 536
++++ +E + + +L++ + + ++ ++ + E +++ E + ++ ++EK++++QE
Sbjct: 330 LREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 389
Query: 537 DSDKDSD----EEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIY 592
+D + E++E+ +E+EE + + E+ E+ E + K++ KT+
Sbjct: 390 QKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMRE------EKKMQEQEKKTRDQE 443
Query: 593 EASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGG------PKKKQK---- 642
E + I + E + ++ K + +W ++ P++K+K
Sbjct: 444 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503
Query: 643 KKAKNKEDS--EKDEK-RDEER---QKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSC 696
+K + +E+ E++EK RD+E Q+ K R M K + E K
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM--- 560
Query: 697 SSDSETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKEND---RTQMQ 753
+ E+ +EK +E D+ EK + E+ + +++E + + Q +
Sbjct: 561 ---WDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 617
Query: 754 PLETLKLEVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFG 813
++ + ++ E E+ +Q KM + EE E E+ + R + K+ E K+
Sbjct: 618 KMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQE 677
Query: 814 QNEAGSEPHIEAHSLELSSLDNKNFSSATE---DEIDQCVKEKKLKRKILGQSSPEKKIR 870
+ + E E +E + + + + E +E +EKK++ + E+K++
Sbjct: 678 KMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQ 737
Score = 44.3 bits (103), Expect = 7e-04
Identities = 89/451 (19%), Positives = 184/451 (40%), Gaps = 70/451 (15%)
Query: 152 EDEKEEESSEE--EDEDKRRLNDELLGKVVSVVSATERTEWYPALVISPSCNDDITVKKD 209
E EK +E E+ E E+K R +E+ G+ E+ W + + ++D
Sbjct: 502 EQEKMQEQEEKIWEQEEKIRDQEEMWGQ--------EKKMWR---------QEKMREQED 544
Query: 210 QCLVRSFIDSKFYSIARKDIKEVDILNLPESELSTKPGLQKASIFLKTRVVPDNWKMDIS 269
Q + + K +K + + + E K Q+ + + R+ KM
Sbjct: 545 QMWEQ---EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 601
Query: 270 EILESSSSDDEDGPAEENDEEKEKEAKKTEEEVPEEELDPEERDNFLQQLYKFMEDRGTP 329
E + + E+ E++EK ++ E+ +EE E+ + +Q K E + P
Sbjct: 602 EEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 661
Query: 330 INKPPVLGYKDLNLFKLFRLVYHQGGCDNIDSGAVWKQIYMDLGIPILNSAASYNVKTAY 389
K + ++ + + + +W+Q M+ KT
Sbjct: 662 EQKEKLWEHEKMQEQEKMQ----------EQEEKIWEQEKME-------------KKTQE 698
Query: 390 RKYLYGFEEYCRSANIQFRTVHHHEPKVKEEKKDLEESMEEALKLDQEMPLTEVKS-EPE 448
++ +E R + ++ E K++EE++ + E E+ + +++M E + E E
Sbjct: 699 QEKKTWDQEKMR----EEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQE 754
Query: 449 ENIDSNSESEREEIELKSPRGRRRIARDVNSIKKEIEEEK---TEDKLKDNDTENKDVDD 505
E + E E+ L P + ++ +K E+EK E+K++D + + + ++
Sbjct: 755 EKMWEQEEKMWEQQRL--PEQKEKLWEH----EKMQEQEKIWEQEEKMRDQEEKMRGQEE 808
Query: 506 DYETAEKK---ENELLLGRKNTPKQKEKKIKKQEDSDKDSDEE-EEKSQEREETESKCDS 561
E+K + E + G++ +E+K+ QE+ +E+ EEK Q +EE + +
Sbjct: 809 KMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEE 868
Query: 562 EGEEDEEDMEPCLTGTKVKVKYGRGKTQKIY 592
+ EE M + + + RG+ +KIY
Sbjct: 869 KMRGQEEKM-------REQEEKMRGQEEKIY 892
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 69.7 bits (169), Expect = 2e-11
Identities = 100/493 (20%), Positives = 211/493 (42%), Gaps = 26/493 (5%)
Query: 406 QFRTVHHHEPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELK 465
Q + E +++E++K+L E +E + + E E EE + E RE+ E
Sbjct: 274 QEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKM 333
Query: 466 SPRGRRRIARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKK-ENELLLGRKNT 524
+ R ++ ++E + E+++ + D ++ ++ EK E E + +
Sbjct: 334 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEER 393
Query: 525 PKQKEKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKV--- 581
+++EKK++++E++ + E+EEK Q++EE + +E++E + L K K+
Sbjct: 394 IREREKKMREEEETMR---EQEEKMQKQEENMWE-----QEEKEWQQQRLPEQKEKLWEQ 445
Query: 582 KYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQ 641
+ + + +KI+E + +I D E ++ W R ++ + + +W ++ ++Q
Sbjct: 446 EKMQEQEEKIWE---QEEKIRDQEEMWGQEKKMW--RQEKMREQEDQMWEQEEKMRDQEQ 500
Query: 642 KKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSE 701
K + + E+DE+ R+K +R R K KT E K+
Sbjct: 501 KMWDQEERMWEQDERL---REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMR 557
Query: 702 TEDAL---EKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETL 758
E+ + EK + EE ++++ EK + ++K+ E+ K+ K ++ + +
Sbjct: 558 EEERMREREKKMREEEEMMREQEEKMQE-QEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 616
Query: 759 KLEVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAG 818
K+ E E +Q M + EE +E E+ + + + ++ + + GQ E
Sbjct: 617 KMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 676
Query: 819 SEPHIEAHSLELSSLDNKNFSSATEDEI-DQCVKEKKLKRKILGQSS-PEKKIRIENGME 876
E + E + + E+++ Q K + K+ GQ EK+ RI + E
Sbjct: 677 REQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKE 736
Query: 877 MTNTVSQERTSDC 889
E C
Sbjct: 737 KMQERLPEHEERC 749
Score = 57.0 bits (136), Expect = 1e-07
Identities = 59/266 (22%), Positives = 119/266 (44%), Gaps = 47/266 (17%)
Query: 414 EPKVKEEKKDLEES-----MEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPR 468
E K++EEKK E+ EE ++ ++ M E K EE + E + +E E K
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM-- 590
Query: 469 GRRRIARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQK 528
R+ E EE+ E + K + E K + + E +++ E++ ++ +++
Sbjct: 591 ------REQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQ 644
Query: 529 EKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKT 588
E+K+ +QE+ + E+EEK +E+EE + + E EE M+ + + + RG+
Sbjct: 645 EEKMWEQEEKMR---EQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQE 701
Query: 589 QKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNK 648
+K+ W W + ++ +W G ++ ++K+ + +
Sbjct: 702 EKM-----------------------WGQEEKMWGQEEK-MW-----GQEEMREKEERIR 732
Query: 649 EDSEKDEKR--DEERQKSKRGRPPLK 672
+ EK ++R + E + S+ PP K
Sbjct: 733 DQKEKMQERLPEHEERCSEPCLPPSK 758
Score = 50.1 bits (118), Expect = 1e-05
Identities = 39/181 (21%), Positives = 87/181 (48%), Gaps = 7/181 (3%)
Query: 406 QFRTVHHHEPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESER---EEI 462
Q + E K++E+++ + E E+ + +++M E K +E D E E E+
Sbjct: 579 QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE 638
Query: 463 ELKSPRGRRRIARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKK---ENELLL 519
E + + ++ ++E + + E+K++ + + ++ ++ + E+K + E +
Sbjct: 639 EKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMR 698
Query: 520 GRKNTPKQKEKKIKKQEDSDKDSDEEEEKSQE-REETESKCDSEGEEDEEDMEPCLTGTK 578
G++ +E+K+ QE+ +E EK + R++ E + E +E EPCL +K
Sbjct: 699 GQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSK 758
Query: 579 V 579
V
Sbjct: 759 V 759
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 68.6 bits (166), Expect = 4e-11
Identities = 109/511 (21%), Positives = 185/511 (36%), Gaps = 105/511 (20%)
Query: 433 KLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSIKKEIEEEKTEDK 492
KL P+ + + + DS SE EE E++ P ++ V + + + K K
Sbjct: 67 KLQANGPVAKKAKKKASSSDSEDSSEEEE-EVQGPPAKKAA---VPAKRVGLPPGKAAAK 122
Query: 493 LKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDKDSDEEEEKSQER 552
++ + + DDD E +KK+ + G K K + KK + SD DSD E
Sbjct: 123 ASESSSSEESSDDDDEEDQKKQ-PVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSE----- 176
Query: 553 EETESKCDSEGEEDEEDMEPCLTGTKVKV-------------KYGRGKTQKIYEASIKST 599
+E ++ +P +T VK K GK +S S+
Sbjct: 177 -----------DEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSS 225
Query: 600 EIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKK------------QKKKAKN 647
DD E ++ K PKK+ +K+ +
Sbjct: 226 SSDDSE-------------------EEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSS 266
Query: 648 KEDSEKDEKRDEER-QKSKRG---------RPPLKSTLSSNMPYGL----SKTANSEGKS 693
EDS DE+ ++++ K+K G PP K +L + P +SE S
Sbjct: 267 SEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSS 326
Query: 694 DSCSSDSETEDALEKNLINEELSLKD-------ELEKNENLNDDKLDEENPKISAHILKE 746
D S SE E + + + K E + + +D D+E P A K
Sbjct: 327 DESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKN 386
Query: 747 NDR--------TQMQPLETLKLEVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSK 798
+ ++P K VG ++++ + EE E+ K +K
Sbjct: 387 SSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTK 446
Query: 799 TKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDEIDQCVKEKKLKRK 858
K + + + + Q GS SS D+ + SS E+E KK +K
Sbjct: 447 PKATAKAALSLPA-KQAPQGSRD---------SSSDSDSSSSEEEEEKTSKSAVKKKPQK 496
Query: 859 ILGQSSPEKKIRIENG-MEMTNTVSQERTSD 888
+ G ++P K + G E +N+ S + +S+
Sbjct: 497 VAGGAAPSKPASAKKGKAESSNSSSSDDSSE 527
Score = 51.6 bits (122), Expect = 4e-06
Identities = 111/599 (18%), Positives = 216/599 (36%), Gaps = 96/599 (16%)
Query: 619 YDEWVKADRIIW-PLDKGGPKKKQKKKAKNKEDSEKDEKRDEERQ--KSKRGRPPLKSTL 675
Y W+K+ ++ L GP K+ KK + DSE + +EE Q +K+ P K
Sbjct: 54 YSFWLKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRV- 112
Query: 676 SSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINE-------------ELSLKDELE 722
+P G + SE S SSD + E+ +K + + + + + +
Sbjct: 113 --GLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSD 170
Query: 723 KNENLNDDKLDEENPKISAHILKENDRTQMQPLETL-KLEVGENEQIVQIFGNKMEKTEE 781
+ + D+ + PKI+ +K + +P K+ G+ + +
Sbjct: 171 SDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDS 230
Query: 782 VKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSSA 841
+++A +PK KT + K +A + P ++ S E SS D
Sbjct: 231 EEEKAAATPK------KTVPKKQVVAK----APVKAATTPTRKSSSSEDSSSDE------ 274
Query: 842 TEDEIDQCVKEK------------KLKRKILGQSSPEKKIRIENGMEMTNTVSQER---- 885
E+E + +K K +K LG P+K + + +E + S E
Sbjct: 275 -EEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSS 333
Query: 886 -------TSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQ---LTSERFDSPAE 935
T + K ++ E ++ S +E ++ + T + PA
Sbjct: 334 EEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAV 393
Query: 936 ETVNIPLK-EDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPA 994
T + +K P+ G + L+ + D +E+ SSE +
Sbjct: 394 TTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEES---------SSSEEEKTKKMVAT 444
Query: 995 LPPVVQHNFSVASPLTLSQDESRSVKSESDITIEVDSIAEESQEGLCERESANGFETNVA 1054
P +++ P + SR S+S DS + E +E + + VA
Sbjct: 445 TKPKATAKAALSLPAKQAPQGSRDSSSDS------DSSSSEEEEEKTSKSAVKKKPQKVA 498
Query: 1055 SGTCSIIVQERESREKGQKRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSEDL 1114
G + S +KG+ S+ +S ++ + E+ G+ S
Sbjct: 499 GGAAP---SKPASAKKGKAESSNSSSS------------DDSSEEEEEKLKGKGSPRPQA 543
Query: 1115 PVLDNSNELDNMNSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHA 1173
P + ++ L N + + E+ +E +K + S+ ++ +R++ K+ E A
Sbjct: 544 PKANGTSALTAQNG--KAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQA 600
Score = 32.7 bits (73), Expect = 2.1
Identities = 21/111 (18%), Positives = 49/111 (44%), Gaps = 6/111 (5%)
Query: 445 SEPEENIDSNSESEREEIELKSPRGRRRIARDVNSIKKEIEEEKTEDKLKDNDTENKDVD 504
S EE+ S E ++ + P+ + A S+ + + + D D+D+ + + +
Sbjct: 425 SSEEESSSSEEEKTKKMVATTKPKATAKAAL---SLPAKQAPQGSRDSSSDSDSSSSEEE 481
Query: 505 DDYET---AEKKENELLLGRKNTPKQKEKKIKKQEDSDKDSDEEEEKSQER 552
++ + +KK ++ G + KK K + + SD+ E+ +E+
Sbjct: 482 EEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEK 532
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 67.8 bits (164), Expect = 6e-11
Identities = 158/817 (19%), Positives = 300/817 (36%), Gaps = 151/817 (18%)
Query: 402 SANIQFRTVHHHEPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSES---- 457
S +++ + EPK ++E ++E L++++ L++ + + N++ NS+
Sbjct: 538 SVDLEESSTKSLEPKAAR----IKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQY 593
Query: 458 --------------EREEI----ELKSPRGR---RRIARDVNSIKKEIEEEKTEDKLK-- 494
E+E+I ELK + + AR ++ ++E K E KL+
Sbjct: 594 EEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKLERE 653
Query: 495 --------------DNDTENKDVDDDYETAE------KKENELLLGRKNTPKQKE----- 529
+T+ +DV E +E +K+ L K+ K
Sbjct: 654 HKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHL 713
Query: 530 KKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGE-----EDEEDMEPCLTGTKVKVKYG 584
K + K+E E EK+ ++ K +G+ DE ++ G KV+
Sbjct: 714 KSLLKKEVKSSKEKPEREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQ 773
Query: 585 RGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKK 644
+ Q + K+ + G + I D+ K+ KK+
Sbjct: 774 KQSQQTKLSSDDKTERKSKHRNERKLSVLG-----KDGKPVSEYIIKTDENVRKENNKKE 828
Query: 645 AKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKS-DSCSSDSETE 703
+ + K E + SK + L S +G++ SE S D C DS
Sbjct: 829 RRLSAEKTKAEHKSRRSSDSKIQKDSLGS-----KQHGITLQRRSESYSEDKCDMDSTNM 883
Query: 704 DALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVG 763
D+ NL EE+ K E + ++L ++KL +LK +TQ + ++ ++ E+
Sbjct: 884 DS---NLKPEEVVHK-EKRRTKSLLEEKL----------VLKSKSKTQGKQVKVVETELQ 929
Query: 764 ENEQIVQIFGNKMEKTEEVKKE--AEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEP 821
E K T + KE E++ K R+SK +D E E G EP
Sbjct: 930 EG-------ATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFE----------ETGVEP 972
Query: 822 HIE-----AHSLELSSLDNKNFSSATED-EIDQCVKEKKLKRKI--------LGQSSPEK 867
+E AHS + S A E + D+ +L+RK+ L SS +
Sbjct: 973 VLETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDI 1032
Query: 868 KIRIEN------GMEMTNTVSQERTSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQC 921
K + EN G E+ ++ + R G+ + + G SL E +
Sbjct: 1033 KKKDENKSDDKDGKEVDSSHEKAR-----GNSSLMEKKLSRRLCENRRG--SLSQEMAKG 1085
Query: 922 IQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVE 981
++L + +P+ ++ P K G TL+ + ++ E ++ +V+
Sbjct: 1086 EEKLAANTLSTPSGSSLQRPKKS--------GDMTLIPEQEPMEIDSEPGVENVFEVSKT 1137
Query: 982 SSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVKSESDITIEV-----DSIAEES 1036
N+ + + N + T+ +DE R+ ++S T + +
Sbjct: 1138 QDNRNN-----NSQQDIDSENMKQKTSATVQKDELRTCTADSKATAPAYKPGRGTGVNSN 1192
Query: 1037 QEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNSGLMAKKQKRTPKRTSA 1096
E + S + ++ S + E+E +G + +S + + P
Sbjct: 1193 SEKHADHRSTLTKKMHIQSAVSKMNPGEKEPIHRGTTEVNI-DSETVHRMLLSAPSENDR 1251
Query: 1097 AAKNEKNGTGQSSDSEDLPVLDNSNELDNMNSTERIS 1133
KN KN + ++ L++S LD+ S ++
Sbjct: 1252 VQKNLKNTAAEEHVAQGDATLEHSTNLDSSPSLSSVT 1288
Score = 65.1 bits (157), Expect = 4e-10
Identities = 197/939 (20%), Positives = 355/939 (37%), Gaps = 186/939 (19%)
Query: 150 VTEDEKEEESSEEEDEDKRRLN-------DELLGKVVSVVSATERTEWYPALVISPSCND 202
VT D EE +DE+K + N D GK SV A + + S S +D
Sbjct: 428 VTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDS-DD 486
Query: 203 DITV---------KKDQCLVRSFIDSKFYSIARKDIKEV-----------DILNLPESEL 242
++TV +K++ L+R I+ + RK E ++L ES
Sbjct: 487 ELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESST 546
Query: 243 -STKPGLQKASIFLKTRVVPDNWKMDISEILESSSSD-DEDGPAEENDEEKEKEAKKTEE 300
S +P + LK R V + K+ +S+ + S + +E+ ++ EE KE KT E
Sbjct: 547 KSLEPKAARIKEVLKERKVLEK-KVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSE 605
Query: 301 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID 360
+E++ + K + + P +KP + L++ +N +
Sbjct: 606 HCEKEKISSSKE-------LKHVHAKSEP-SKPARRLSESLHVVD-----------ENKN 646
Query: 361 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE 420
+ ++ P++ T K E C + ++ +E +K++
Sbjct: 647 ESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKD 706
Query: 421 KKD---LEESMEEALKLDQEMPLTEVKSEPEENIDSNSE-------SEREEIELKSPRGR 470
+ L+ +++ +K +E P E K+ E+ + + +E EL S
Sbjct: 707 DSETPHLKSLLKKEVKSSKEKPERE-KTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKG 765
Query: 471 RRIARDVNSIKKEIE---EEKTEDKLKDNDTENKDV--DDDYETAE---------KKENE 516
++ ++ ++ + ++KTE K K + V D +E +KEN
Sbjct: 766 LKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENN 825
Query: 517 LLLGRKNTPKQK-EKKIKKQEDSDKDSDEEEEKS-----QEREE--TESKCDSEGEEDEE 568
R + K K E K ++ DS D K Q R E +E KCD + +
Sbjct: 826 KKERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDS 885
Query: 569 DMEPCLTGTKVKVKYGRGKTQKIYEAS--IKSTEIDDGEVLYLVHYYGWNVRYDEWVKAD 626
+++P + V + +T+ + E +KS G+ + +V
Sbjct: 886 NLKP-----EEVVHKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVE--------------- 925
Query: 627 RIIWPLDKGGPK-----KKQKKKAKNKEDSEKDEK-RDEERQKSKRGRPPLKSTLSSNMP 680
L +G K K K+K + DSEK K + E++ + G P+ T SS+
Sbjct: 926 ---TELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETGVEPVLETASSS-A 981
Query: 681 YGLSK---------TANSEGKSDSCSSDSETEDALEKNLINEEL--SLKDELEKNENLND 729
+ K A + KSD S+ + E L + L S KD +K+EN +D
Sbjct: 982 HSTQKDSSHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSD 1041
Query: 730 DKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTEE-VKKEAEK 788
DK +E S+H + + M+ + L + EN + +M K EE +
Sbjct: 1042 DKDGKEVD--SSHEKARGNSSLME--KKLSRRLCENRR--GSLSQEMAKGEEKLAANTLS 1095
Query: 789 SPKGKG--RRSKTKDLSLEIIKISSFGQNEAGSEPHIE----------------AHSLEL 830
+P G R K+ D++L I E SEP +E ++
Sbjct: 1096 TPSGSSLQRPKKSGDMTL----IPEQEPMEIDSEPGVENVFEVSKTQDNRNNNSQQDIDS 1151
Query: 831 SSLDNKNFSSATEDEIDQCVKEKKL-----------------KRKILGQSSPEKKIRIEN 873
++ K ++ +DE+ C + K ++ +S+ KK+ I++
Sbjct: 1152 ENMKQKTSATVQKDELRTCTADSKATAPAYKPGRGTGVNSNSEKHADHRSTLTKKMHIQS 1211
Query: 874 GMEMTNTVSQE-----RTSDCIGSEGMKN--LNFEQHFERENEGMPSLIAESNQCIQQLT 926
+ N +E T I SE + L+ +R + + + AE + T
Sbjct: 1212 AVSKMNPGEKEPIHRGTTEVNIDSETVHRMLLSAPSENDRVQKNLKNTAAEEHVAQGDAT 1271
Query: 927 SERF----DSPAEETVN-IPLKE--DEDAMPLIGPETLV 958
E SP+ +V +PL+E D D +PL T++
Sbjct: 1272 LEHSTNLDSSPSLSSVTVVPLRESYDPDVIPLFDKRTVL 1310
Score = 61.2 bits (147), Expect = 6e-09
Identities = 155/821 (18%), Positives = 314/821 (38%), Gaps = 93/821 (11%)
Query: 426 ESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIAR--DVNSIKKE 483
++ E A K P T+ ++ E + ++ E+ + G + + + +
Sbjct: 228 KTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTAD-SGGEGLETAPKSEEFSDLPCP 286
Query: 484 IEEEKTEDKLKDN-DTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDKDS 542
+EE K K +N NKDV + + K + + ++ ++ E+K +K+E ++K
Sbjct: 287 VEEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKF 346
Query: 543 DEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTEID 602
D ++ ++ + K E E + + K K G + + S+ +++D
Sbjct: 347 DHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKE-----DFSLIDSDVD 401
Query: 603 DGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEERQ 662
+ + + ++ E + ++ + + KNK++ K + D
Sbjct: 402 GLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEG 461
Query: 663 KSKRGR------PPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELS 716
K+K R P L S S+ L+ + S E E+ L + IN E
Sbjct: 462 KTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQ------SIAKEKEERLLRRQINREKL 515
Query: 717 LKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKM 776
+ +K E K + S+ L+E+ ++P EV + ++++ K+
Sbjct: 516 EEKRKQKAEKTKSSKTKGQGR--SSVDLEESSTKSLEPKAARIKEVLKERKVLE---KKV 570
Query: 777 EKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNE--AGSEPHIEAHSLELSSLD 834
+++ KK++ + ++ + ++ S E +K S + E + S+ H+ S
Sbjct: 571 ALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSKP 630
Query: 835 NKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQER---TSDCIG 891
+ S + +D+ E KL+R+ ++S + +E E T+T +R S+
Sbjct: 631 ARRLSESLH-VVDENKNESKLEREHKRRTS--TPVIMEGVQEETDTRDVKRQVERSEICT 687
Query: 892 SEGMK---NLNFEQHFERENEGMPSL--IAESNQCIQQLTSERFDSPAEETVNIPLKEDE 946
E K L E+H ++++ P L + + + ER +P+E+ +++ K
Sbjct: 688 EEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSEDKLSVKHKYKG 747
Query: 947 DAMPLIGPETLVCH-------EVDLDDLDEKDKTSIEDVAVESSESNSLVSI-------P 992
D M G ET + E ++ ++ K S +D S+ + +
Sbjct: 748 DCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGK 807
Query: 993 PALPPVVQHNFSV-----ASPLTLSQDESRS---VKSESDITIEVDSIAEESQEGLCERE 1044
P +++ + +V LS +++++ + SD I+ DS+ + +R
Sbjct: 808 PVSEYIIKTDENVRKENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQHGITLQRR 867
Query: 1045 SANGFE-------TNVASGTCSIIVQERESR-------EKGQKRPSDGNSGLMAK----- 1085
S + E TN+ S V +E R EK + G K
Sbjct: 868 SESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVETE 927
Query: 1086 ------KQKRTPKRTSAAAKNEKNGTGQ-SSDSEDLPVLDNSNE------LDNMNSTERI 1132
KQ TPK E + Q S ED P + E + +ST++
Sbjct: 928 LQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETGVEPVLETASSSAHSTQKD 987
Query: 1133 SFLQEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHA 1173
S + KL ++ Y S K +T R+ K R + H+
Sbjct: 988 SSHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHS 1028
Score = 60.5 bits (145), Expect = 1e-08
Identities = 159/779 (20%), Positives = 308/779 (39%), Gaps = 92/779 (11%)
Query: 416 KVKEEKKDLEESMEEALKLDQEMPLTEVKS-----EPEENIDSNSESEREEIELKSPRGR 470
KVK+EK+ E+ +E +LKL E + K+ E IDS+ + +I + S
Sbjct: 357 KVKDEKQAKEKEVE-SLKLPSEKNSNKAKTVEGTKEDFSLIDSDVDG-LTDITVSSVH-- 412
Query: 471 RRIARDVNSIKKEIEEEK-TEDKLK------DNDTENKDVDDDYETAEKKENELLLGRKN 523
D++S +++ EEE T D ++ D++ +NK +T++ E + R
Sbjct: 413 ---TSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHA 469
Query: 524 TPKQKEKKIKKQEDSDKDSDEEEEK---SQEREETESKCDSEGEEDEEDMEPCLTGTKVK 580
+ K DSD + E+ + ++E+EE + E+ EE + TK
Sbjct: 470 YVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSS 529
Query: 581 VKYGRGKTQ-KIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKK 639
G+G++ + E+S KS E R E +K +++ K K
Sbjct: 530 KTKGQGRSSVDLEESSTKSLEPKAA-------------RIKEVLKERKVLEK--KVALSK 574
Query: 640 KQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSD 699
K+KK ++N E++ K +++ EE K TL ++ K ++S+ +
Sbjct: 575 KRKKDSRNVEENSKKKQQYEEDSKE---------TLKTSEHCEKEKISSSK---ELKHVH 622
Query: 700 SETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPK-ISAHILKENDRTQMQPLETL 758
+++E + ++E L + DE N N+ KL+ E+ + S ++ E + ET
Sbjct: 623 AKSEPSKPARRLSESLHVVDE-----NKNESKLEREHKRRTSTPVIMEGVQE-----ETD 672
Query: 759 KLEVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAG 818
+V + +I + +K + K + K K L + +K SS + E
Sbjct: 673 TRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVK-SSKEKPERE 731
Query: 819 SEPHIEAHSLELSSLDNKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMT 878
P + S++ + + E E+ K K++ I QS + K+ ++ E
Sbjct: 732 KTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQ-QTKLSSDDKTERK 790
Query: 879 NTVSQERTSDCIGSEGMKNLNF----EQHFERENEGMPSLIAESNQCIQQLTSERFDSPA 934
+ ER +G +G + +++ +EN ++ + + DS
Sbjct: 791 SKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEHKSRRSSDSKI 850
Query: 935 EETV------NIPLK-------EDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVE 981
++ I L+ ED+ M ++ + E + + K+ +E+ V
Sbjct: 851 QKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVL 910
Query: 982 SSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVKSESD----ITIEVDSIAEESQ 1037
S+S + + +Q + + E + +++S+ +E E
Sbjct: 911 KSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETGV 970
Query: 1038 EGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNSGLMAKKQKRTPKRTSA- 1096
E + E S++ T S + + +E K D S + +K K S
Sbjct: 971 EPVLETASSSAHSTQKDSSHRAKLPLAKEK----YKSDKDSTSTRLERKLSDGHKSRSLK 1026
Query: 1097 -AAKNEKNGTGQSSDSEDLPVLDNSNELDNMNSTERISFLQEKLQEIRKYYMSLKSEVA 1154
++K+ K SD +D +D+S+E NS+ L +L E R+ SL E+A
Sbjct: 1027 HSSKDIKKKDENKSDDKDGKEVDSSHEKARGNSSLMEKKLSRRLCENRR--GSLSQEMA 1083
Score = 47.4 bits (111), Expect = 8e-05
Identities = 58/272 (21%), Positives = 117/272 (43%), Gaps = 28/272 (10%)
Query: 417 VKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARD 476
V+ + K++EE K ++ + EP++N D +S E + + P ++
Sbjct: 2754 VEADPKEVEEEERHMPKRKRKQHYLSSEDEPDDNPDV-LDSRIETAQRQCPETEPHDTKE 2812
Query: 477 VNSIKKEIEE-EKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQ 535
NS +++EE KT + + + D+Y ++E G K P+Q + K
Sbjct: 2813 ENS--RDLEELPKTSSETNSTTSRVMEEKDEYSSSETT------GEK--PEQNDDDTIKS 2862
Query: 536 EDSDKDSDEEEEKSQERE---ET--ESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQK 590
++ D+ + ++ + R+ ET + K DS+ + +E + +K+KV ++
Sbjct: 2863 QEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTDTGIVTVEQSPSSSKLKVMQTDESNKE 2922
Query: 591 IYEASIKSTEIDDGE--VLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKA--- 645
+S DDGE ++ V G + V D + P++K++K
Sbjct: 2923 TANLQERSISNDDGEEKIVTSVRRRGRKPKRSLTVSDDA-----ESSEPERKRQKSVSDP 2977
Query: 646 -KNKEDSEKDEKRDEERQKSKRGRPPLKSTLS 676
++K++ E DE+ +EE + G +T S
Sbjct: 2978 VEDKKEQESDEEEEEEEEDEPSGATTRSTTRS 3009
Score = 45.1 bits (105), Expect = 4e-04
Identities = 80/398 (20%), Positives = 157/398 (39%), Gaps = 44/398 (11%)
Query: 224 IARKDIKEVDILNLPESELSTKPG----LQKASIFLKTRVVPDNWKMDISEILESSSSDD 279
+ ++ K +IL PES KP LQ+ + + + +N +E + S S +
Sbjct: 2676 VPSEEEKNGEILAPPESLCGGKPSGIAELQREPLLVNESLNVENSGFRTNEEIHSESYNK 2735
Query: 280 EDGPAEENDEEKEKEAKKTE---EEVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVL 336
+ + D + E +EV EEE +R +Q Y ED P + P VL
Sbjct: 2736 GEISSGRKDNAEAISGHSVEADPKEVEEEERHMPKRKR--KQHYLSSEDE--PDDNPDVL 2791
Query: 337 GYKDLNLFKLFRLVYHQGGCDNIDSGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGF 396
R+ Q C + ++ DL + +++ N T+ + +
Sbjct: 2792 DS---------RIETAQRQCPETEPHDTKEENSRDLE-ELPKTSSETNSTTS--RVMEEK 2839
Query: 397 EEYCRSANIQFRTVHHHEPKVKEEKKDLEESMEEALKLDQEMPL-TEVKSEPEENIDSNS 455
+EY S + + + +K +++D ++ ++ P+ T +K + + D+
Sbjct: 2840 DEYSSSETTGEKPEQNDDDTIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTDTGI 2899
Query: 456 ESEREEIELKSPRGRRRIARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKEN 515
+ + SP + + KE + E + ++D E K V K +
Sbjct: 2900 VTVEQ-----SPSSSKLKVMQTDESNKETANLQ-ERSISNDDGEEKIVTSVRRRGRKPKR 2953
Query: 516 ELLLG---RKNTPKQKEKKI-------KKQEDSDKDSDEEEEKSQEREETESKCDSEGEE 565
L + + P++K +K KK+++SD++ +EEEE T S SE +
Sbjct: 2954 SLTVSDDAESSEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEPSGATTRSTTRSEAQR 3013
Query: 566 DEEDMEPCLTGTKVKVKYG---RGKTQKIYEASIKSTE 600
+ + P + + G RG+ Q++ EA +K +
Sbjct: 3014 SKTQLSPSIKRKREVSPPGARTRGQ-QRVEEAPVKKAK 3050
Score = 44.7 bits (104), Expect = 5e-04
Identities = 49/216 (22%), Positives = 82/216 (37%), Gaps = 12/216 (5%)
Query: 97 DERTLRRTSLCLKGERHFAESET---LDQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTED 153
D R C + E H + E L++LP T+ E T T+R +
Sbjct: 2792 DSRIETAQRQCPETEPHDTKEENSRDLEELPKTSSETNST------TSRVMEEKDEYSSS 2845
Query: 154 EKEEESSEEEDEDKRRLNDELLGKVVSVVSATERTEWYPALVISPSCNDDITVKKDQCLV 213
E E E+ D+D + +E + + + R YP + + DD V
Sbjct: 2846 ETTGEKPEQNDDDTIKSQEE--DQPIIIKRKRGRPRKYP-VETTLKMKDDSKTDTGIVTV 2902
Query: 214 RSFIDSKFYSIARKDIKEVDILNLPESELSTKPGLQKASIFLKTRVVPDNWKMDISEILE 273
S + + D + NL E +S G +K ++ R + +S+ E
Sbjct: 2903 EQSPSSSKLKVMQTDESNKETANLQERSISNDDGEEKIVTSVRRRGRKPKRSLTVSDDAE 2962
Query: 274 SSSSDDEDGPAEENDEEKEKEAKKTEEEVPEEELDP 309
SS + + + + E +KE + EEE EEE +P
Sbjct: 2963 SSEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEP 2998
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo
sapiens]
Length = 2191
Score = 67.4 bits (163), Expect = 8e-11
Identities = 44/149 (29%), Positives = 79/149 (53%), Gaps = 6/149 (4%)
Query: 251 ASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEEEVPEE-ELDP 309
AS+ L + P K+ + + +E P E+ +K + T E++ + EL
Sbjct: 951 ASVGLADMMSPGESKLPLPL---KADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGN 1007
Query: 310 E-ERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNIDSGAVWKQI 368
E ER ++ + FME+RG+P++ P +G K L+LF+L+ V GG ++ W+++
Sbjct: 1008 EPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWREL 1067
Query: 369 YMDLGIPILNSAASYNVKTAYRKYLYGFE 397
+L + +SAAS ++K Y +YL+ FE
Sbjct: 1068 ATNLNVGTSSSAAS-SLKKQYIQYLFAFE 1095
Score = 30.8 bits (68), Expect = 8.1
Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 23/96 (23%)
Query: 265 KMDISEILESSSSDDEDGPAEENDEE----KEKEAKKTEEE--------VPEEELDPEER 312
K D + + S ++ED ++DEE +E++++KTE + P+ DP+E+
Sbjct: 1660 KDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEK 1719
Query: 313 DNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFR 348
+Q KF +K P+ K NLF + R
Sbjct: 1720 P---KQASKF--------DKLPIKIVKKNNLFVVDR 1744
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo
sapiens]
Length = 2178
Score = 67.4 bits (163), Expect = 8e-11
Identities = 44/149 (29%), Positives = 79/149 (53%), Gaps = 6/149 (4%)
Query: 251 ASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEEEVPEE-ELDP 309
AS+ L + P K+ + + +E P E+ +K + T E++ + EL
Sbjct: 938 ASVGLADMMSPGESKLPLPL---KADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGN 994
Query: 310 E-ERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNIDSGAVWKQI 368
E ER ++ + FME+RG+P++ P +G K L+LF+L+ V GG ++ W+++
Sbjct: 995 EPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWREL 1054
Query: 369 YMDLGIPILNSAASYNVKTAYRKYLYGFE 397
+L + +SAAS ++K Y +YL+ FE
Sbjct: 1055 ATNLNVGTSSSAAS-SLKKQYIQYLFAFE 1082
Score = 30.8 bits (68), Expect = 8.1
Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 23/96 (23%)
Query: 265 KMDISEILESSSSDDEDGPAEENDEE----KEKEAKKTEEE--------VPEEELDPEER 312
K D + + S ++ED ++DEE +E++++KTE + P+ DP+E+
Sbjct: 1647 KDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEK 1706
Query: 313 DNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFR 348
+Q KF +K P+ K NLF + R
Sbjct: 1707 P---KQASKF--------DKLPIKIVKKNNLFVVDR 1731
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 65.1 bits (157), Expect = 4e-10
Identities = 136/689 (19%), Positives = 250/689 (36%), Gaps = 134/689 (19%)
Query: 441 TEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSIKKEIEEEKTEDKLKDNDTEN 500
T +K + EE I +SE+E + +EE+ E ++ + TE
Sbjct: 434 THIKVKSEEKIKVVEKSEKETVI--------------------VEEQTEETQVTEEVTEE 473
Query: 501 KDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDKDSDEEEEKSQEREETESKCD 560
++ + E +++E G + + E++ K + S E+E KS +EE +S +
Sbjct: 474 EEKEAKEEEGKEEEG----GEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAE 529
Query: 561 SEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYD 620
++ E EE P + K K K + KS E ++ +
Sbjct: 530 AKSPEKEEAKSPAEVKSPEKAK-SPAKEEAKSPPEAKSPEKEEAKS-------------- 574
Query: 621 EWVKADRIIWPLDKGGPKKKQ---KKKAKNKEDSEKDEKR----DEERQKSKRGRPPLKS 673
P + P+K + K++AK+ +++ EK EE + + P+K
Sbjct: 575 ----------PAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE 624
Query: 674 TLSS----NMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDELEKNENLND 729
S P E KS + E E+A K+ + +K E + E
Sbjct: 625 EAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEA--KSPEKAKSPVKAEAKSPEKAKS 682
Query: 730 D-KLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQI---VQIFGNKMEKTEEVKKE 785
K + ++P+ + +KE ++ + +K E E+ V+ EK + KE
Sbjct: 683 PVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKE 742
Query: 786 AEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDE 845
KSP+ K K L ++ + + + EA S F +
Sbjct: 743 EAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPA--------------DKFPEKAKSP 788
Query: 846 IDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNFEQHFE 905
+ + VK + + L + + + I E+ + V +E E+ E
Sbjct: 789 VKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEE----------------EKPQE 832
Query: 906 RENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCHEVDLD 965
+ + P E T E+ DS EE P KE P+ V E +
Sbjct: 833 VKVKEPPKKAEEEKAPATPKTEEKKDSKKEEA---PKKE--------APKPKV--EEKKE 879
Query: 966 DLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVKSESDI 1025
EK K S + E +E V P P A P ++++ K E D
Sbjct: 880 PAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKP----KEKTEVAKKEPD- 934
Query: 1026 TIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSD-GNSGLMA 1084
D+ A+E + ++E+A ++++++E+ K+P + + A
Sbjct: 935 ----DAKAKEPSKPAEKKEAA---------------PEKKDTKEEKAKKPEEKPKTEAKA 975
Query: 1085 KKQKRTPKRTSAAAKNEKNGTGQSSDSED 1113
K+ +T + + K EK S+D +D
Sbjct: 976 KEDDKTLSKEPSKPKAEKAEKSSSTDQKD 1004
Score = 57.4 bits (137), Expect = 8e-08
Identities = 119/629 (18%), Positives = 245/629 (38%), Gaps = 63/629 (10%)
Query: 376 ILNSAASYNVK-TAYRKYLYGFEEYCRSANIQFRTVH----------HHEPKVKEEKKDL 424
+LN + +++ AYRK L G E I F H + K +E+ K +
Sbjct: 388 LLNVKMALDIEIAAYRKLLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVV 447
Query: 425 EESMEEALKLDQEMPLTEVKSE--------------PEENIDSNSESEREEIELKSPRGR 470
E+S +E + ++++ T+V E EE E+E E E KSP
Sbjct: 448 EKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAE 507
Query: 471 RRIARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEK 530
+ + + EE K+ + K + E + ++ EK ++ K+ P+ K
Sbjct: 508 EAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSP 567
Query: 531 KIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEE------DEEDMEPCLTGTKVKVKYG 584
+ ++ + + E+ KS +EE +S +++ E EE P + VK +
Sbjct: 568 EKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAK 627
Query: 585 RGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKA---------DRIIWPLDKG 635
K E + T+ + + E K+ ++ P+ K
Sbjct: 628 SPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPV-KA 686
Query: 636 GPKKKQKKKAKNKEDSEKDEKR----DEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEG 691
K +K K+ KE+++ EK EE + ++ + P+K + P E
Sbjct: 687 EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKE--EAKTPEKAKSPVKEEA 744
Query: 692 KSDSCSSDSETEDALEKNLINEELSLKDELEKNENLNDDKL------DEENPKISAHILK 745
KS + E L+ + K+E + +K + ++P+ + LK
Sbjct: 745 KSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLK 804
Query: 746 ENDRT---QMQPLETLKLEVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDL 802
E+ + ++ E +K V E E+ ++ + K E +K A +PK + ++ K+
Sbjct: 805 EDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEK-APATPKTEEKKDSKKEE 863
Query: 803 SLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDEIDQCVKEKKLKRKILGQ 862
+ + K + + E EP +E + S ++ K + + ++ KE K ++
Sbjct: 864 APK--KEAPKPKVEEKKEPAVE--KPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKED 919
Query: 863 SSPEKKIRIENGMEMTNTVSQERTSDCIGSEGM-KNLNFEQHFERENEGMPSLIAESNQC 921
+ P++K + E + ++E + E + + ++ ++ E P A++ +
Sbjct: 920 AKPKEKTEVAK-KEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKED 978
Query: 922 IQQLTSERFDSPAEETVNIPLKEDEDAMP 950
+ L+ E AE+ + +D+ P
Sbjct: 979 DKTLSKEPSKPKAEKAEKSSSTDQKDSKP 1007
Score = 54.3 bits (129), Expect = 7e-07
Identities = 121/667 (18%), Positives = 252/667 (37%), Gaps = 80/667 (11%)
Query: 7 PAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPLRVGAIV 66
P +V T + K E KIK V++ K V++++ V ++ + +
Sbjct: 427 PKIPSVSTHIKVK-----SEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEE 481
Query: 67 ETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETLDQLPLT 126
E + +G +E ++ + + ++ S + + AE+++ ++
Sbjct: 482 EGKEEEGGEEEE--AEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAK 539
Query: 127 NPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEES---SEEEDEDKRRLNDELLGKVVSVVS 183
+P +P AK + S P + ++EE+ +E + +K + + K +
Sbjct: 540 SPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAK 599
Query: 184 ATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDS--KFYSIARKDIKEVDILNLPESE 241
+ E+ + P + S + + K++ + + S K S +++ K + PE E
Sbjct: 600 SPEKAK-SPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKE 658
Query: 242 LSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEEE 301
+ P K+ + + + P+ K + E+ S + P +E + K +K +
Sbjct: 659 EAKSPEKAKSPVKAEAKS-PEKAKSPVKA--EAKSPEKAKSPVKE----EAKSPEKAKSP 711
Query: 302 VPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNIDS 361
V EE PE+ + +++ K E +P+ + K +
Sbjct: 712 VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK---------------------A 750
Query: 362 GAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEEK 421
+ K +D+ P + A ++ K F E +S VKEE
Sbjct: 751 KSPEKAKTLDVKSPEAKTPAKEEARSPADK----FPEKAKSP-------------VKEEV 793
Query: 422 KDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSIK 481
K E++ + LK D + P E+ + E E + +E+++K P + + + K
Sbjct: 794 KSPEKA-KSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPK 852
Query: 482 KEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDKD 541
E +++ +++ + V++ E A +K E + K + +KK+ E
Sbjct: 853 TEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPA 912
Query: 542 SDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTEI 601
E +E ++ +E+TE + +D + EP K + + T++ E + K E
Sbjct: 913 KVEVKEDAKPKEKTE--VAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKE--EKAKKPEEK 968
Query: 602 DDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEER 661
E KA L K K K +K K+ +KD K E+
Sbjct: 969 PKTE-----------------AKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKA 1011
Query: 662 QKSKRGR 668
+ K +
Sbjct: 1012 TEDKAAK 1018
Score = 46.2 bits (108), Expect = 2e-04
Identities = 101/477 (21%), Positives = 177/477 (37%), Gaps = 57/477 (11%)
Query: 416 KVKEEKKDLEESMEEALKLDQEMPLT--EVKSEPEENIDSNSESEREEIELKSPRGRR-- 471
K K K+ +S EA ++E + EVKS PE+ E + E KSP +
Sbjct: 549 KAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKS-PEKAKSPAKEEAKSPAEAKSPEKAKSP 607
Query: 472 --RIARDVNSIKKEIEEE-------KTEDKLKDNDTENKDVDDDYETAEKKENELLLGRK 522
A+ K ++EE K+ +K K E + ++ EK+E + K
Sbjct: 608 VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAK 667
Query: 523 NTPKQKEKKIKKQEDSDK--DSDEEEEKSQEREETES--KCDSEGEEDEEDMEPCLTGTK 578
+ K + K +K + K E+ KS +EE +S K S +E+ + E + K
Sbjct: 668 SPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVK 727
Query: 579 VKVKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPK 638
+ K + E + + E + + +A P DK K
Sbjct: 728 EEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARS---PADKFPEK 784
Query: 639 KK----------QKKKAKNKEDSEKDEK------------RDEERQKSKRGRPPLKSTLS 676
K +K K+ KED++ EK ++EE+ + + + P K
Sbjct: 785 AKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEE 844
Query: 677 SNMPYGLSKTANSEGKSDSCSSDSETEDALEKNL-------INEELSLKDELEKNENLND 729
P T +E K DS ++ ++A + + + + K E +K E +
Sbjct: 845 EKAP----ATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDK 900
Query: 730 DKLDEENPKISAHILKENDRTQMQPLETLKLEVGE-NEQIVQIFGNKMEKTEEVKKEAEK 788
K+ + A + + D + E K E + + K E E K E+
Sbjct: 901 KKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEE 960
Query: 789 SPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDE 845
K + KT+ + E K S ++ +E ++ S + D+K ATED+
Sbjct: 961 KAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTD--QKDSKPPEKATEDK 1015
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 65.1 bits (157), Expect = 4e-10
Identities = 109/589 (18%), Positives = 235/589 (39%), Gaps = 86/589 (14%)
Query: 399 YCRSANIQFRTVHHHEPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEE-------NI 451
Y R+ + + + ++E+ ++ E ++ ++ + S P+E N
Sbjct: 27 YQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNT 86
Query: 452 DSNSESEREEIELKSPRGRRRIARDVNSIK--KEIEEEKTEDKLKDNDTENKDVDDDYET 509
+ E +E + R RR R +++ KE + T+ L ++ + ET
Sbjct: 87 QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENET 146
Query: 510 AEKKENELLLGRKNTPKQKEKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEED 569
EK+E K+ +Q+ +I++ E K + + + E + E K + E EE+E+
Sbjct: 147 TEKEE-------KSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDK-EKEEEEEEKP 198
Query: 570 MEPCLTGTKVKVKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRII 629
+ +V+V T+ E + S + +G++
Sbjct: 199 KRGSIGENQVEVMVEEKTTESQEETVVMS--LKNGQI----------------------- 233
Query: 630 WPLDKGGPKKKQKKKAKNKEDS--EKDEKRDEERQKSKRGR--PPLKSTLSSNMPYGLS- 684
PK++++++ + E S EK E+ D+ER +++R R + + + ++
Sbjct: 234 ---SSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIAD 290
Query: 685 KTANSEGKSDSCSSDSETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHIL 744
+ A E + + + + E +A E+ + EE E + + + EE +I
Sbjct: 291 ERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRI----- 345
Query: 745 KENDRTQMQPLETLKLEV-----------GENEQIVQIFGNKMEKTEEVKKEAEKSPKGK 793
KE ++ + + +K E E E+ ++ K K E KK A + K K
Sbjct: 346 KEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIK 405
Query: 794 GRRSKTK-------DLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDEI 846
G + + K + + K+ + + G E + + ++K E +
Sbjct: 406 GEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKD 465
Query: 847 DQCVKEKKLKRKILGQSSPEK---KIRIENGMEMTNTVSQ-ERTSDCIGSEGMKNLNFEQ 902
++ K+K+ K ++ +K +++ +NG MT+ + E T G +
Sbjct: 466 EKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVD----- 520
Query: 903 HFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPL 951
+E EG P + E+ + +++L R ++ +EE + K+ E A+ L
Sbjct: 521 --TKEAEGAPQV--EAGKRLEELRRRRGETESEEFEKLKQKQQEAALEL 565
Score = 56.2 bits (134), Expect = 2e-07
Identities = 85/470 (18%), Positives = 178/470 (37%), Gaps = 86/470 (18%)
Query: 409 TVHHHEPKVKEEKKDLEESMEEAL------KLDQEMPLTEVKSEPEENIDSNSESEREEI 462
++ ++ +V E+K E E + ++ E P E + E + S+ E EE
Sbjct: 202 SIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEED 261
Query: 463 ELKSPRGRRRIARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRK 522
+ ++ R R+ + K +++K D+ + E K + E E +E E + +
Sbjct: 262 KERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEE 321
Query: 523 NTPKQKEKKIKKQE-----DSDKDSDEE----EEKSQEREETESKCDSEGEEDEEDMEPC 573
++ ++IK++E + + +EE EE+ + +EE + + E+ E
Sbjct: 322 KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKA 381
Query: 574 LTGTKVKVKYGRGKTQKIYEASIKSTEID---DGEVLYLVHYYGWNVRYDEWVKADRIIW 630
+ + K K + E IK +++ +G+ W
Sbjct: 382 KVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGK------------------------W 417
Query: 631 PLDKGGPKKKQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSE 690
+K + K + K+ EK K +R+K + +P K E
Sbjct: 418 VNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFK---------------KEE 462
Query: 691 GKSDSCSSDSETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRT 750
K + D E ++ +K +++ + + K +N + H LK + T
Sbjct: 463 IKDEKIKKDKEPKE-----------EVKSFMDRKKGFTEVK--SQNGEFMTHKLKHTENT 509
Query: 751 QMQPLETLKLEVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKIS 810
+P ++ E E Q+ K + EE+++ RR +T+ E +K
Sbjct: 510 FSRPGGRASVDTKEAEGAPQVEAGK--RLEELRR----------RRGETESEEFEKLKQK 557
Query: 811 SFGQNEAGSE-PHIEAHSLELSSLDNKNFSSATEDEIDQCVKEKKLKRKI 859
Q EA E ++ E + + ++E D+ ++E++ KR++
Sbjct: 558 ---QQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRL 604
Score = 53.9 bits (128), Expect = 9e-07
Identities = 51/196 (26%), Positives = 90/196 (45%), Gaps = 15/196 (7%)
Query: 409 TVHHHEPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPR 468
T E K ++ KKD E E +D++ TEVKS+ E + + + E P
Sbjct: 457 TFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFM--THKLKHTENTFSRPG 514
Query: 469 GRRRIARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQK 528
GR + ++E K ++L+ E + +++E ++K+ E L + K++
Sbjct: 515 GRASVDTKEAEGAPQVEAGKRLEELRRRRGETES--EEFEKLKQKQQEAALELEELKKKR 572
Query: 529 EKKIK---------KQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKV 579
E++ K KQE++D+ EEEEK + +EE E + E+ ++ E L+ K
Sbjct: 573 EERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 632
Query: 580 KVK--YGRGKTQKIYE 593
K +G + KI E
Sbjct: 633 PFKCFTPKGSSLKIEE 648
Score = 46.6 bits (109), Expect = 1e-04
Identities = 80/431 (18%), Positives = 172/431 (39%), Gaps = 58/431 (13%)
Query: 481 KKEIEEEKTED-KLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQED-- 537
++E+ +K E+ +L+ + DDD E A ++ + KQ+E+ + + D
Sbjct: 7 RRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQV 66
Query: 538 -------------------SDKDSDEEE---EKSQEREETESKCDSEGEEDEEDMEPCLT 575
+ + D+E E+ REE K E E +++ +P +T
Sbjct: 67 EVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT 126
Query: 576 GTKVKVKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKG 635
+ + R + + + E + RY E + + + K
Sbjct: 127 DASLSLPSRRMQNDTAENETTEKEEKSESR----------QERY-EIEETETVTKSYQKN 175
Query: 636 GPKKKQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDS 695
+ ++ K KED EK+E+ +E+ ++ G ++ + +T K+
Sbjct: 176 DWRDAEENK---KEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQ 232
Query: 696 CSSDSETEDALEKNLINEELSLKDELEKNENLNDD----KLD-EENPKISAH----ILKE 746
SS+ E + E+ ++E+S +++E+ + + +L+ EE +I A I E
Sbjct: 233 ISSE-EPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADE 291
Query: 747 NDRTQMQ----PLETLKLEVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGR-RSKTKD 801
R + + E + E E E++ + E+ + +K+E +++ + + R + + K
Sbjct: 292 RARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKR 351
Query: 802 LSLEIIKISSFGQNEAGSEPHIEAHSLELSSLD----NKNFSSATEDEIDQCVKEKKLKR 857
+ E +I + A A E + ++ NK + +K +K+++
Sbjct: 352 AAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQ 411
Query: 858 KILGQSSPEKK 868
KI G+ EKK
Sbjct: 412 KIEGKWVNEKK 422
Score = 31.2 bits (69), Expect = 6.2
Identities = 43/235 (18%), Positives = 94/235 (40%), Gaps = 10/235 (4%)
Query: 100 TLRRTSLCLKGER---HFAESETLD--QLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDE 154
T+ SL L R AE+ET + + + E + T +++ E+
Sbjct: 124 TITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEEN 183
Query: 155 KEEESSEEEDEDKRRLNDELLGKVVSVVSATERTEWYPALVISPSCNDDITVKKDQCLVR 214
K+E+ +EE+E+++ + V V+ + TE V+ N I+ ++ +
Sbjct: 184 KKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPK--QE 241
Query: 215 SFIDSKFYSIARKDIKEVDILNLPESELSTKPGLQKASIFLK--TRVVPDNWKMDISEIL 272
+ I+ + E + E+E + ++ I + ++ + +++ E
Sbjct: 242 EEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKA 301
Query: 273 ESSSSDDEDGPAEENDEEKEKEAKKTEEEVPEEE-LDPEERDNFLQQLYKFMEDR 326
+ + + E E+EK A + + + EEE EER ++ + E+R
Sbjct: 302 AAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER 356
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 64.7 bits (156), Expect = 5e-10
Identities = 136/655 (20%), Positives = 252/655 (38%), Gaps = 98/655 (14%)
Query: 490 EDKLKDNDTENKDVDDDYETAE------KKENELLLGRKNTPKQKEKKIKKQEDSDKDSD 543
+ K K D+ D+D D AE KE E +K+ K+K++K K+ D D
Sbjct: 4 KQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQE---PQKSKGKKKKEKKKQDFDEDDILK 60
Query: 544 EEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTEIDD 603
E EE S E + ++ ++ + E+ E T K K +GK Q + + E D
Sbjct: 61 ELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKD 120
Query: 604 GE----VLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDE 659
+ V Y + D++ K P G +K KK E+ E + K+ +
Sbjct: 121 SKSKKTAKPKVEMYSGSDDDDDFNKL-----PKKAKGKAQKSNKKWDGSEEDEDNSKKIK 175
Query: 660 ER-----------------QKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSET 702
ER Q K + K+ N+ G ++ ++ K + +
Sbjct: 176 ERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESG-NEDDDASFKIKTVAQKKAE 234
Query: 703 EDALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEV 762
+ E+ +EE + +L++ E L K D+ K S +E ET+K +V
Sbjct: 235 KKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEE---------ETVKSKV 285
Query: 763 GENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPH 822
+ ++ K E + + E K K ++ K K E K G ++A
Sbjct: 286 TVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKK-KGEKEEKEKEKKKGPSKA----T 340
Query: 823 IEAHSLELSSLDNKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVS 882
++A L+ L E+E + +E+++KR ++ +++ R+E
Sbjct: 341 VKAMQEALAKLKE-------EEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQK 393
Query: 883 QERTSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETV--NI 940
++ + + EG K L Q R A + ++ L ++ + P+++++
Sbjct: 394 EKERKERLKKEG-KLLTKSQREAR---------ARAEATLKLLQAQGVEVPSKDSLPKKR 443
Query: 941 PLKEDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQ 1000
P+ ED+ + P+ L EV + ++ + + V E PP + P +
Sbjct: 444 PIYEDKKRKKI--PQQLESKEVS-ESMELCAAVEVMEQGVPEKEET-----PPPVEPEEE 495
Query: 1001 HNFSVASP---LTLSQDESRSVKSESDITIEVDSIAEESQEGLCERESANGFETNVASGT 1057
+ A ++ DE + + IEV EE +E E E E+
Sbjct: 496 EDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEE--EEEEEEDEES------ 547
Query: 1058 CSIIVQERESREKGQKRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSE 1112
E E E+G+ S+G+ + +K + ++ S ++K SSDSE
Sbjct: 548 ------EEEEEEEGESEGSEGDE----EDEKVSDEKDSGKTLDKKPSKEMSSDSE 592
Score = 57.8 bits (138), Expect = 6e-08
Identities = 84/342 (24%), Positives = 149/342 (43%), Gaps = 23/342 (6%)
Query: 403 ANIQFRTVHHHEPKVKE-EKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREE 461
A+ + +TV + + KE E+K +E + KL ++ L K + + +S + E E
Sbjct: 221 ASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEET 280
Query: 462 IELKSPRGRRRIARDVNSIKKEIEEEKTEDKLKDN---DTENKDVDDDYETAEKKENELL 518
++ K + D I E+ +T +D+ D + KD E+KE E
Sbjct: 281 VKSK-------VTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKK 333
Query: 519 LG-RKNTPKQKEKKIKK-QEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTG 576
G K T K ++ + K +E+ ++ EEEE+ + EE E+K E ++E E
Sbjct: 334 KGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQK 393
Query: 577 TKVKVKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGG 636
K + K K K+ S + L L+ G V + + R P+ +
Sbjct: 394 EKER-KERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKR---PIYEDK 449
Query: 637 PKKKQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSD-- 694
+KK ++ ++KE SE E + ++G P + T P T ++ G D
Sbjct: 450 KRKKIPQQLESKEVSESME-LCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDA-GLDDWE 507
Query: 695 SCSSDSETEDALEKNLINEELSLKDELEKNENLNDDKLDEEN 736
+ +SD ETE +E N ++ E+ E E+ E +++ DEE+
Sbjct: 508 AMASDEETE-KVEGNKVHIEVKENPE-EEEEEEEEEEEDEES 547
Score = 56.2 bits (134), Expect = 2e-07
Identities = 160/744 (21%), Positives = 276/744 (37%), Gaps = 165/744 (22%)
Query: 95 DGDERTLRRTSLCLKGERHFAESETLDQLPL-TNPEHFGTPVIAKKTNRGRRSSLPVTED 153
D D+ L L+ + A+ ET+ P N E F + KK +G++ S D
Sbjct: 54 DEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSF----D 109
Query: 154 EKEEESSEEEDEDKRRLNDELLGKVVSVVSATERTEWYPALVISPSCNDDITVK------ 207
+ + E E++D ++ +A + E Y S S +DD K
Sbjct: 110 DNDSEELEDKDSKSKK-------------TAKPKVEMY-----SGSDDDDDFNKLPKKAK 151
Query: 208 -KDQCLVRSFIDSKFYSIARKDIKEVDILNLPESELSTKPGLQKASIFLKTRV-VPDNWK 265
K Q + + S+ K IKE +N S+ ++ FL++R N K
Sbjct: 152 GKAQKSNKKWDGSEEDEDNSKKIKERSRIN------SSGESGDESDEFLQSRKGQKKNQK 205
Query: 266 MDISEILESSSSDDEDG-----PAEENDEEKEKEAKKTEEE-------VPEEELDPEERD 313
+ES + DD+ A++ E+KE+E KK +EE +EEL+ ++D
Sbjct: 206 NKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKD 265
Query: 314 NFLQQ--LYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNIDSGAVWKQIYMD 371
Q+ KF E+ V ++ +D
Sbjct: 266 QSKQKESQRKFEEE-------------------------------------TVKSKVTVD 288
Query: 372 LGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEEKKDLEESMEEA 431
G+ I S TA G ++ + + K K K ++M+EA
Sbjct: 289 TGV-IPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEA 347
Query: 432 L-KLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSIKKEIEEEKTE 490
L KL +E K E EE I EE+E K + R+ ++ KK+ E+E+ E
Sbjct: 348 LAKLKEEE--ERQKREEEERI-----KRLEELEAKR-KEEERLEQEKRERKKQKEKERKE 399
Query: 491 DKLKDNDTENKDVDDDYETAE------KKENELLLGRKNTPK-------QKEKKIKKQED 537
K+ K + AE + + + + + PK +K KKI +Q +
Sbjct: 400 RLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLE 459
Query: 538 SDKDSDE---------EEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKT 588
S + S+ E+ E+EET + E EED ED G
Sbjct: 460 SKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTED---------------AGLD 504
Query: 589 QKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNK 648
AS + TE +G +++ K P+++++++ + +
Sbjct: 505 DWEAMASDEETEKVEGNKVHIE----------------------VKENPEEEEEEEEEEE 542
Query: 649 EDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYG--LSKTANSEGKSDS--CSSDSETED 704
ED E +E+ +EE + +S G L K + E SDS S D T++
Sbjct: 543 EDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKE 602
Query: 705 ALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQ-MQPLETLKLEVG 763
+ + K LE ++N+N +KL + H+ + +T+ + L ++ G
Sbjct: 603 ERAYDKAKRRIE-KRRLEHSKNVNTEKLRAPIICVLGHV--DTGKTKILDKLRHTHVQDG 659
Query: 764 ENEQIVQIFGNKMEKTEEVKKEAE 787
E I Q G E + ++ +
Sbjct: 660 EAGGITQQIGATNVPLEAINEQTK 683
Score = 33.9 bits (76), Expect = 0.96
Identities = 34/135 (25%), Positives = 55/135 (40%), Gaps = 14/135 (10%)
Query: 1042 ERESANGFETNVASGTCSI---IVQERESREKGQKRPSDGNSGLMAKKQKRTPK-RTSAA 1097
++ES FE ++ ++ E + + D N G KK K+ K
Sbjct: 269 QKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEK 328
Query: 1098 AKNEKNGTGQSSDS---EDLPVLDNSNELDNMNSTERISFLQEKLQEIRKYYMSLKSEVA 1154
K +K G +++ E L L E ERI L+E L+ RK L+ E
Sbjct: 329 EKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEE-LEAKRKEEERLEQE-- 385
Query: 1155 TIDRRRKRLKKKDRE 1169
+R+R K+K++E
Sbjct: 386 ----KRERKKQKEKE 396
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 63.2 bits (152), Expect = 1e-09
Identities = 57/264 (21%), Positives = 115/264 (43%), Gaps = 28/264 (10%)
Query: 444 KSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSIKKEIEEEKTEDKLKD--NDTENK 501
K + ++N +S++E E+ + +D +KK + K +DK KD DTE+
Sbjct: 285 KKDTKKNAKKSSDAESED--------SKDAKKDSKKVKKNV---KKDDKKKDVKKDTEST 333
Query: 502 DVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDKDSDEEEEKSQEREETESKCDS 561
D + E+K+ + +K K +KK K+ D++ + K + K S
Sbjct: 334 DAESGDSKDERKDTKK--DKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKAS 391
Query: 562 EGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDE 621
+ ++ ++D + T + + ++QK + K ++ D+ + +V+ DE
Sbjct: 392 KNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKK----------SVKNDE 441
Query: 622 WVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPY 681
D P KG KK +K + K K+DS+KD+K+ + ++ ++ L + +
Sbjct: 442 -ESTDADSEP--KGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKH 498
Query: 682 GLSKTANSEGKSDSCSSDSETEDA 705
K + + D+E+ DA
Sbjct: 499 SKEKKGSKKDIKKDARKDTESTDA 522
Score = 58.9 bits (141), Expect = 3e-08
Identities = 111/569 (19%), Positives = 223/569 (39%), Gaps = 107/569 (18%)
Query: 371 DLGIPILNSAA-SYNVK----TAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEEKKDLE 425
D IPI S+ S+N K T + G + R Q H + K++E +K
Sbjct: 15 DNSIPISESSRKSWNQKHFALTFPKPLQRGTNDKSRPLKSQITVTRHDKRKLEEGQKPAH 74
Query: 426 ESMEEALKLDQEMP--------------LTEVKSEPEENIDSNSESEREEIELKSPRGRR 471
+ + + + + P L K+ ++ S+ E+ LK ++
Sbjct: 75 KWIRHSFRKILQWPPIYTAAREQTPFRHLYTSKTHLKKAEYKKSKDEKGGTPLKKDSKKK 134
Query: 472 RIARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKK 531
+ N K+I EEKT+ + N+ + + +E + K+++ N Q K
Sbjct: 135 GGSYATNPESKQIVEEKTK---RQNEADKTPLKSSHENEQSKKSK-SSSETNPESQNSKT 190
Query: 532 IKK--QEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEP---CLTGTKVKVKY--- 583
+ K + KDS ++ + E T++ + + + +P + + V +
Sbjct: 191 VSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLML 250
Query: 584 -GRGKTQKI-YEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQ 641
G+ + I ++A +++ ++ + ++++Y ++ K D K KK
Sbjct: 251 VGQSDDESINFDAWLRNYSQNNSK--------NYSLKYTKYTKKD------TKKNAKKSS 296
Query: 642 KKKAKNKEDSEKDEKRDEER-QKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSC---- 696
++++ +D++KD K+ ++ +K + + K T S++ G SK + K D
Sbjct: 297 DAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKK 356
Query: 697 ------------SSDSETEDALEKNLINEELSLK----------------------DELE 722
S+D+E+ DA K+ N+ +LK ELE
Sbjct: 357 DDKKKDTKKYPESTDTESGDA--KDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELE 414
Query: 723 KNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEK--TE 780
E+ D+K D+++ K +ND K G++++ G K EK +
Sbjct: 415 SKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPK---GDSKK-----GKKDEKKGKK 466
Query: 781 EVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSS 840
+ KK+ +K K S + LE+ K + + GS+ I+ D + +
Sbjct: 467 DSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKK--------DARKDTE 518
Query: 841 ATEDEIDQCVKEK-KLKRKILGQSSPEKK 868
+T+ E D+ K K KI G + ++
Sbjct: 519 STDAEFDESSKTGFKTSTKIKGSDTESEE 547
Score = 48.9 bits (115), Expect = 3e-05
Identities = 66/275 (24%), Positives = 115/275 (41%), Gaps = 31/275 (11%)
Query: 418 KEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDV 477
K+ KKD ++ ++ K D + +E + D+ ++S + K+ ++ +
Sbjct: 345 KDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKIT 404
Query: 478 NSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQE- 536
S E E E E + KD + KD D + + K + E + PK KK KK E
Sbjct: 405 FSTDSESELESKESQ-KDEKKDKKDSKTDNKKSVKNDEEST-DADSEPKGDSKKGKKDEK 462
Query: 537 ----DSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIY 592
DS KD D++++ + E TE + D E ++D++ + G+K +K K +
Sbjct: 463 KGKKDSKKD-DKKKDAKKNAESTEMESDLELKKDKKHSKE-KKGSKKDIKKDARKDTEST 520
Query: 593 EAS--------------IKSTEIDDGEVLYLVHYYGWNVRYDE--WVKADRIIWPLDKGG 636
+A IK ++ + E LY G + DE A+ + L+
Sbjct: 521 DAEFDESSKTGFKTSTKIKGSDTESEESLYKP---GAKKKIDESDGTSANSKMEGLES-- 575
Query: 637 PKKKQKKKAKNKEDSEKDEKRDEERQKSKRGRPPL 671
K+ + +K +EK EK R R +PPL
Sbjct: 576 -KRGFRMSSKKTTFNEKGEKASTGRVPPSREKPPL 609
Score = 47.0 bits (110), Expect = 1e-04
Identities = 92/475 (19%), Positives = 187/475 (39%), Gaps = 61/475 (12%)
Query: 108 LKGERHFAESETLDQLPLTNPEHFGTPVIAK----KTNRGRRSSLPVTEDEKEEESSEEE 163
LK +S+ TNPE + ++K K + ++S + +++ ++
Sbjct: 163 LKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKK 222
Query: 164 DEDKRRLNDELLGKVVSVVSATERTEWYPALVISPSCNDDITVKKDQCLVR-SFIDSKFY 222
D + + +++ + ++ S S ++ +DD ++ D L S +SK Y
Sbjct: 223 DLKRSKTSNDPISEICSENSLNVD------FLMLVGQSDDESINFDAWLRNYSQNNSKNY 276
Query: 223 SI-----ARKDIKEVDILNLPESELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSS 277
S+ +KD K+ + ++E +K S +K V D+ K D+ + ES+ +
Sbjct: 277 SLKYTKYTKKDTKK-NAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDA 335
Query: 278 DDEDGPAEENDEEKEKEAKKTEEEVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLG 337
+ D E D +K+K+ K +++ + + PE D K + + K
Sbjct: 336 ESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDA-KDARNDSRNLKKASKND 394
Query: 338 YKDLNLFKLFRLVYHQGGCDNIDSGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFE 397
K + K+ + ++ +S K+ D KT +K + E
Sbjct: 395 DKKKDAKKITFSTDSESELESKESQKDEKKDKKD-------------SKTDNKKSVKNDE 441
Query: 398 EYCRSANIQFRTVHHHEPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSES 457
E S + + K+EKK ++S ++ K D + K+ ++S+ E
Sbjct: 442 E---STDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAK------KNAESTEMESDLEL 492
Query: 458 EREEIELKSPRGRRR-----IARDVNSIKKEIEEE-----KTEDKLKDNDTEN------- 500
++++ K +G ++ +D S E +E KT K+K +DTE+
Sbjct: 493 KKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKP 552
Query: 501 ---KDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDKDSDEEEEKSQER 552
K +D+ T+ + E L ++ + KK E +K S S+E+
Sbjct: 553 GAKKKIDESDGTSANSKMEGLESKRGF-RMSSKKTTFNEKGEKASTGRVPPSREK 606
Score = 46.6 bits (109), Expect = 1e-04
Identities = 107/506 (21%), Positives = 204/506 (40%), Gaps = 52/506 (10%)
Query: 634 KGG-----PKKKQKKKAKNKEDSEKDE---KRDEERQKSKRGRPPLKSTLSSNMPYGLSK 685
KGG P+ KQ + K K +E D+ K E ++SK+ + ++ S +SK
Sbjct: 134 KGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSK 193
Query: 686 TANSEGKSDSCSSD-SETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHIL 744
+ + K DS +S + TE KN N + LK N+ +++ + ++
Sbjct: 194 NCSQKDKKDSKNSKKTNTEFLHTKN--NPKKDLKRSKTSNDPISEICSENSLNVDFLMLV 251
Query: 745 KENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSL 804
++D + L+ N + + K K ++ KK A+KS + SK
Sbjct: 252 GQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTK-KDTKKNAKKSSDAESEDSKDAKKDS 310
Query: 805 EIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDEIDQCVKEKKLKRKILGQSS 864
+ +K + +++ + + S + S D+K+ T+ + +KKLK+
Sbjct: 311 KKVK-KNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKD------KKKLKKD------ 357
Query: 865 PEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNFEQHFERENEGMP-SLIAESN-QCI 922
+KK + E T+T S + S +K + +++ + + S +ES +
Sbjct: 358 -DKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESK 416
Query: 923 QQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVES 982
+ E+ D +T N ++++ E + D + K S +D +
Sbjct: 417 ESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKD 476
Query: 983 SESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSV-KSESDITIEVDSIAE-ESQEGL 1040
++ N+ + + S L L +D+ S K S I+ D+ + ES +
Sbjct: 477 AKKNA-------------ESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAE 523
Query: 1041 CERESANGFETNVASGTCSIIVQERESREKGQKR--PSDGNS------GLMAKKQKR-TP 1091
+ S GF+T+ +E + +K+ SDG S GL +K+ R +
Sbjct: 524 FDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSS 583
Query: 1092 KRTSAAAKNEKNGTGQSSDSEDLPVL 1117
K+T+ K EK TG+ S + P L
Sbjct: 584 KKTTFNEKGEKASTGRVPPSREKPPL 609
Score = 43.9 bits (102), Expect = 0.001
Identities = 49/186 (26%), Positives = 86/186 (46%), Gaps = 29/186 (15%)
Query: 405 IQFRTVHHHEPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIEL 464
I F T E + KE +KD ++ +++ K D + VK++ EE+ D++SE + +
Sbjct: 403 ITFSTDSESELESKESQKDEKKDKKDS-KTDNKK---SVKND-EESTDADSEPKGD---- 453
Query: 465 KSPRGRRRIARDVNSIKKEIEEEKTEDKLKD--NDTENKDVDDDYETAEKKENELLLGRK 522
S +G++ KK ++ K +DK KD + E+ +++ D E + K++
Sbjct: 454 -SKKGKK-------DEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKH------S 499
Query: 523 NTPKQKEKKIKKQEDSDKDSDEEE--EKSQEREETESKCDSEGEEDEEDMEPCLTGTKVK 580
K +K IKK D +S + E E S+ +T +K E EE + G K K
Sbjct: 500 KEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYK--PGAKKK 557
Query: 581 VKYGRG 586
+ G
Sbjct: 558 IDESDG 563
Score = 37.0 bits (84), Expect = 0.11
Identities = 83/421 (19%), Positives = 154/421 (36%), Gaps = 88/421 (20%)
Query: 775 KMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLD 834
K K E+ +K K KG T S +I++ + QNEA P +H E S
Sbjct: 116 KKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSK-- 173
Query: 835 NKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEG 894
K K +++PE +N ++ SQ+ D S+
Sbjct: 174 ---------------------KSKSSSETNPES----QNSKTVSKNCSQKDKKD---SKN 205
Query: 895 MKNLNFEQHFERENEGMPSLIAE-SNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIG 953
K N E + N ++ SN I ++ SE ++N+ D + L+G
Sbjct: 206 SKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSEN-------SLNV------DFLMLVG 252
Query: 954 PETLVCHEVDLDDLDEKDKTSIE-DVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLS 1012
+ D SI D + + N+ N+S+
Sbjct: 253 ---------------QSDDESINFDAWLRNYSQNN------------SKNYSLKYTKYTK 285
Query: 1013 QDESRSVKSESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQ 1072
+D ++ K SD E A++ + + + + + +V T S + +S+++ +
Sbjct: 286 KDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERK 345
Query: 1073 KRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSEDLPVLDNSNELDNMNSTERI 1132
D KK K+ K K + +S+D+E D N+ N+ ++
Sbjct: 346 DTKKD------KKKLKKDDK------KKDTKKYPESTDTESGDAKDARNDSRNL---KKA 390
Query: 1133 SFLQEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSS 1192
S +K ++ +K S SE + ++ +KKD++ S + S +D + + S
Sbjct: 391 SKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTD-NKKSVKNDEESTDADSE 449
Query: 1193 P 1193
P
Sbjct: 450 P 450
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 62.8 bits (151), Expect = 2e-09
Identities = 82/388 (21%), Positives = 147/388 (37%), Gaps = 43/388 (11%)
Query: 445 SEPEENIDSNSESEREEIELKSPRGRRRIARDVNSIKKEIEEEKTEDKLKDNDTENKDVD 504
S+ EE+ DS + E +E E + A + E+E ED D D ++ + D
Sbjct: 145 SDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEED 204
Query: 505 DDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDKDSDEEEEKSQEREETESKCDSEGE 564
D E E E G+K K ED D++ D+E+E + E+ E D + E
Sbjct: 205 DSEE--EAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDE 262
Query: 565 EDEEDMEPCLTGTKVKVKYGRGKTQKIYEAS---IKSTEIDDGEVLYLVHYYGWNVRY-- 619
E+EE+ E VK G+ K + + + K +++ E + + N+ +
Sbjct: 263 EEEEEEEE----EPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNK 318
Query: 620 ----------DEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEK------------DEKR 657
D + K D + + G +K ++ ED EK + K
Sbjct: 319 SAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKALELTGLKVFGNEIKL 378
Query: 658 DEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSL 717
++ + K + ++ L+ N+PY +++ E D+ ++D K + E
Sbjct: 379 EKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRLVSKDGKSKGIAYIEFKT 438
Query: 718 KDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGN-KM 776
+ + EK ++K E S + ++ Q Q K E + N
Sbjct: 439 EADAEKT---FEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSY 495
Query: 777 EKTEEVKKEA------EKSPKGKGRRSK 798
TEE +E K P+ + +SK
Sbjct: 496 SATEETLQEVFEKATFIKVPQNQNGKSK 523
Score = 57.0 bits (136), Expect = 1e-07
Identities = 87/412 (21%), Positives = 165/412 (40%), Gaps = 49/412 (11%)
Query: 125 LTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEE--DEDKRRLNDELLGKVVSVV 182
+ P G + AK G+ + +++E++++S E+E DED+ DE+ +
Sbjct: 119 VATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAA 178
Query: 183 SATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPESEL 242
+A +E DD + D+ D E D + E +
Sbjct: 179 AAAPASE----------DEDDEDDEDDE---------------DDDDDEED--DSEEEAM 211
Query: 243 STKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEEEV 302
T P K + +VVP K + E +DED +E+DE+ + E + EEE
Sbjct: 212 ETTPAKGKKA----AKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEE 267
Query: 303 PEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLF--RLVYHQGGCDNID 360
EEE E +++ K + K V G + F LF L +++ +
Sbjct: 268 EEEEPVKEAPGKRKKEMAK--QKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNK-SAPELK 324
Query: 361 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE 420
+G ++ + +++ K Y + E+ ++ + V +E K+++
Sbjct: 325 TGI--SDVFAKNDLAVVDVRIGMTRKFGYVDF-ESAEDLEKALELTGLKVFGNEIKLEKP 381
Query: 421 K-KDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNS 479
K KD ++ + L + +P + E +E + + EI L S G+ + +
Sbjct: 382 KGKDSKKERDARTLLAKNLPYKVTQDELKEVFE-----DAAEIRLVSKDGKSKGIAYI-E 435
Query: 480 IKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKK 531
K E + EKT ++ + + + + + Y T EK +N+ G KN+ E K
Sbjct: 436 FKTEADAEKTFEEKQGTEIDGRSI-SLYYTGEKGQNQDYRGGKNSTWSGESK 486
Score = 50.1 bits (118), Expect = 1e-05
Identities = 40/149 (26%), Positives = 73/149 (48%), Gaps = 17/149 (11%)
Query: 418 KEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSE------SEREEIELKSPRGRR 471
++E +D +E A+K P +E + + ++ D + + SE E +E +G++
Sbjct: 161 EDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKK 220
Query: 472 RI----ARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQ 527
+ N + E EEE ED+ D+D E+ + DDD + E++E E K P +
Sbjct: 221 AAKVVPVKAKNVAEDEDEEEDDEDE-DDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGK 279
Query: 528 KEKKIKKQEDSDKDSDEEEEKSQEREETE 556
++K++ KQ+ + E K Q+ E TE
Sbjct: 280 RKKEMAKQKAA------PEAKKQKVEGTE 302
Score = 41.6 bits (96), Expect = 0.005
Identities = 70/353 (19%), Positives = 126/353 (35%), Gaps = 53/353 (15%)
Query: 520 GRKNTPKQKEKKIKKQEDSDKDSDEEEEKSQEREETESK------------CDSEGEEDE 567
G KN K++ ++ED D + DEE+++ ++ +E E + + E +ED+
Sbjct: 133 GAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDD 192
Query: 568 EDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADR 627
ED E + E ++++T + +V NV DE + D
Sbjct: 193 EDDE----------DDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEED- 241
Query: 628 IIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTA 687
+ + + ED E D+ D+E ++ + P+K + A
Sbjct: 242 ------------DEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKA 289
Query: 688 NSEGKSDSCSSDSETEDALEKNLINEELSL-KDELEKNENLNDDKLDEENPKISAHILKE 746
E K TE NL L+ K E ++D + + I
Sbjct: 290 APEAKKQKVEG---TEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMT 346
Query: 747 NDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEI 806
+ LE +++FGN E+K E PKGK + + +L
Sbjct: 347 RKFGYVDFESAEDLEKALELTGLKVFGN------EIKLE---KPKGKDSKKERDARTLLA 397
Query: 807 IKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSSA-----TEDEIDQCVKEKK 854
+ + E +A + L S D K+ A TE + ++ +EK+
Sbjct: 398 KNLPYKVTQDELKEVFEDAAEIRLVSKDGKSKGIAYIEFKTEADAEKTFEEKQ 450
Score = 35.8 bits (81), Expect = 0.25
Identities = 45/179 (25%), Positives = 77/179 (43%), Gaps = 25/179 (13%)
Query: 150 VTEDEKEEESSEEEDEDKRRLNDELL-----GKVVSVVSATERTEWYPALVISPSCNDDI 204
V ED ++EE SE+E++D +E++ GK + SA + +V+SP+ +
Sbjct: 24 VEEDSEDEEMSEDEEDDSS--GEEVVIPQKKGKKAAATSAKK-------VVVSPTKKVAV 74
Query: 205 TVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPESELSTK-------PGLQKASIFLKT 257
+ V + + A+K + + P + +T PG + A+I K
Sbjct: 75 ATPAKKAAVTPGKKAAA-TPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKG 133
Query: 258 RVVPDNWKMDISEILESSSS--DDEDGPAEENDEEK-EKEAKKTEEEVPEEELDPEERD 313
N K + S+ E S D+ED E+ DE++ E A K P E + +E D
Sbjct: 134 AKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDD 192
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.126 0.340
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,178,374
Number of Sequences: 37866
Number of extensions: 2431427
Number of successful extensions: 47698
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 540
Number of HSP's successfully gapped in prelim test: 1190
Number of HSP's that attempted gapping in prelim test: 15799
Number of HSP's gapped (non-prelim): 19682
length of query: 1203
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1089
effective length of database: 13,930,794
effective search space: 15170634666
effective search space used: 15170634666
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.