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Search of human proteins with 217272870
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|217272870 solute carrier family 26, member 9 isoform c [Homo
sapiens]
(459 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|217272870 solute carrier family 26, member 9 isoform c [Homo ... 914 0.0
gi|16418413 solute carrier family 26, member 9 isoform a [Homo s... 914 0.0
gi|217272867 solute carrier family 26, member 9 isoform b [Homo ... 914 0.0
gi|94721259 solute carrier family 26, member 6 isoform 4 [Homo s... 259 3e-69
gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo s... 259 3e-69
gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo s... 258 1e-68
gi|39752683 prestin isoform a [Homo sapiens] 256 2e-68
gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo s... 250 2e-66
gi|45827800 prestin isoform b [Homo sapiens] 232 6e-61
gi|4505697 pendrin [Homo sapiens] 216 3e-56
gi|4557535 solute carrier family 26, member 3 [Homo sapiens] 206 4e-53
gi|100913030 solute carrier family 26 member 2 [Homo sapiens] 169 6e-42
gi|16418457 solute carrier family 26, member 8 isoform a [Homo s... 166 3e-41
gi|20336285 solute carrier family 26, member 8 isoform b [Homo s... 166 3e-41
gi|45827802 prestin isoform c [Homo sapiens] 152 5e-37
gi|47131207 solute carrier family 26, member 1 isoform a [Homo s... 127 2e-29
gi|20336272 solute carrier family 26, member 1 isoform a [Homo s... 127 2e-29
gi|16306483 solute carrier family 26, member 7 isoform a [Homo s... 112 5e-25
gi|20336282 solute carrier family 26, member 7 isoform b [Homo s... 112 5e-25
gi|65506789 solute carrier family 26, member 10 [Homo sapiens] 80 4e-15
gi|85540447 solute carrier family 26, member 11 [Homo sapiens] 63 5e-10
gi|119943102 CREB binding protein isoform b [Homo sapiens] 35 0.11
gi|119943104 CREB binding protein isoform a [Homo sapiens] 35 0.11
gi|150170729 microtubule associated serine/threonine kinase 3 [H... 34 0.32
gi|50054477 olfactory receptor, family 5, subfamily AS, member 1... 34 0.32
gi|122891870 melanoma inhibitory activity family, member 3 [Homo... 33 0.41
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 33 0.41
gi|226498466 T-cell immunoglobulin and mucin domain containing 4... 33 0.54
gi|24233580 synaptonemal complex protein 3 [Homo sapiens] 33 0.54
gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precurso... 33 0.71
>gi|217272870 solute carrier family 26, member 9 isoform c [Homo
sapiens]
Length = 459
Score = 914 bits (2361), Expect = 0.0
Identities = 459/459 (100%), Positives = 459/459 (100%)
Query: 1 MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS 60
MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS
Sbjct: 1 MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS 60
Query: 61 VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP 120
VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP
Sbjct: 61 VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP 120
Query: 121 YYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD 180
YYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD
Sbjct: 121 YYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD 180
Query: 181 IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQ 240
IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQ
Sbjct: 181 IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQ 240
Query: 241 EKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSS 300
EKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSS
Sbjct: 241 EKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSS 300
Query: 301 SPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGK 360
SPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGK
Sbjct: 301 SPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGK 360
Query: 361 IGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQANARDVTPGHNFQG 420
IGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQANARDVTPGHNFQG
Sbjct: 361 IGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQANARDVTPGHNFQG 420
Query: 421 APGDAELSLYDSEEDIRSYWDLEQEMFGSMFHAETLTAL 459
APGDAELSLYDSEEDIRSYWDLEQEMFGSMFHAETLTAL
Sbjct: 421 APGDAELSLYDSEEDIRSYWDLEQEMFGSMFHAETLTAL 459
>gi|16418413 solute carrier family 26, member 9 isoform a [Homo
sapiens]
Length = 791
Score = 914 bits (2361), Expect = 0.0
Identities = 459/459 (100%), Positives = 459/459 (100%)
Query: 1 MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS 60
MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS
Sbjct: 333 MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS 392
Query: 61 VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP 120
VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP
Sbjct: 393 VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP 452
Query: 121 YYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD 180
YYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD
Sbjct: 453 YYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD 512
Query: 181 IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQ 240
IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQ
Sbjct: 513 IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQ 572
Query: 241 EKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSS 300
EKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSS
Sbjct: 573 EKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSS 632
Query: 301 SPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGK 360
SPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGK
Sbjct: 633 SPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGK 692
Query: 361 IGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQANARDVTPGHNFQG 420
IGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQANARDVTPGHNFQG
Sbjct: 693 IGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQANARDVTPGHNFQG 752
Query: 421 APGDAELSLYDSEEDIRSYWDLEQEMFGSMFHAETLTAL 459
APGDAELSLYDSEEDIRSYWDLEQEMFGSMFHAETLTAL
Sbjct: 753 APGDAELSLYDSEEDIRSYWDLEQEMFGSMFHAETLTAL 791
>gi|217272867 solute carrier family 26, member 9 isoform b [Homo
sapiens]
Length = 887
Score = 914 bits (2361), Expect = 0.0
Identities = 459/459 (100%), Positives = 459/459 (100%)
Query: 1 MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS 60
MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS
Sbjct: 333 MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS 392
Query: 61 VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP 120
VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP
Sbjct: 393 VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP 452
Query: 121 YYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD 180
YYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD
Sbjct: 453 YYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD 512
Query: 181 IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQ 240
IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQ
Sbjct: 513 IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQ 572
Query: 241 EKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSS 300
EKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSS
Sbjct: 573 EKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSS 632
Query: 301 SPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGK 360
SPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGK
Sbjct: 633 SPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGK 692
Query: 361 IGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQANARDVTPGHNFQG 420
IGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQANARDVTPGHNFQG
Sbjct: 693 IGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQANARDVTPGHNFQG 752
Query: 421 APGDAELSLYDSEEDIRSYWDLEQEMFGSMFHAETLTAL 459
APGDAELSLYDSEEDIRSYWDLEQEMFGSMFHAETLTAL
Sbjct: 753 APGDAELSLYDSEEDIRSYWDLEQEMFGSMFHAETLTAL 791
>gi|94721259 solute carrier family 26, member 6 isoform 4 [Homo
sapiens]
Length = 738
Score = 259 bits (663), Expect = 3e-69
Identities = 144/412 (34%), Positives = 240/412 (58%), Gaps = 6/412 (1%)
Query: 1 MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS 60
++G+AF++A+V + I +++G+ A +HGY VDSNQE++ALG SN G F+ + C++S
Sbjct: 323 LVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMS 382
Query: 61 VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP 120
+L + GG SQVA SL +++ ++ LG + LPK+VL A+I VNLK L+QL+D
Sbjct: 383 RSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDM 442
Query: 121 YYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD 180
LW+ ++ D IW+V+F ++ L+L G+ V V FS+L+VV +TQ + L QV DTD
Sbjct: 443 RSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTD 502
Query: 181 IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQ 240
IY + Y+ A++++G+K+ + +YFAN+E + + + G+D ++ K+K LKKQ
Sbjct: 503 IYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQ 562
Query: 241 EKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSS 300
E+ +++ Q+ L + + + + + +NN VS S D
Sbjct: 563 EQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMRSNNVEDCKMMQVS----SGDKM 618
Query: 301 SPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGK 360
A + ++AP + S + A P FH+LILD+ +SFVD + +K+L + + +
Sbjct: 619 EDATANGQEDSKAP-DGSTLKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFRE 677
Query: 361 IGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQANARDV 412
I V+V++ H+ V + + G F D S+ KH+F S+HDAV FA + R V
Sbjct: 678 IEVEVYMAACHSPVVSQLEAGHFF-DASITKKHLFASVHDAVTFALQHPRPV 728
>gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo
sapiens]
Length = 759
Score = 259 bits (663), Expect = 3e-69
Identities = 144/412 (34%), Positives = 240/412 (58%), Gaps = 6/412 (1%)
Query: 1 MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS 60
++G+AF++A+V + I +++G+ A +HGY VDSNQE++ALG SN G F+ + C++S
Sbjct: 344 LVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMS 403
Query: 61 VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP 120
+L + GG SQVA SL +++ ++ LG + LPK+VL A+I VNLK L+QL+D
Sbjct: 404 RSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDM 463
Query: 121 YYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD 180
LW+ ++ D IW+V+F ++ L+L G+ V V FS+L+VV +TQ + L QV DTD
Sbjct: 464 RSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTD 523
Query: 181 IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQ 240
IY + Y+ A++++G+K+ + +YFAN+E + + + G+D ++ K+K LKKQ
Sbjct: 524 IYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQ 583
Query: 241 EKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSS 300
E+ +++ Q+ L + + + + + +NN VS S D
Sbjct: 584 EQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMRSNNVEDCKMMQVS----SGDKM 639
Query: 301 SPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGK 360
A + ++AP + S + A P FH+LILD+ +SFVD + +K+L + + +
Sbjct: 640 EDATANGQEDSKAP-DGSTLKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFRE 698
Query: 361 IGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQANARDV 412
I V+V++ H+ V + + G F D S+ KH+F S+HDAV FA + R V
Sbjct: 699 IEVEVYMAACHSPVVSQLEAGHFF-DASITKKHLFASVHDAVTFALQHPRPV 749
>gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo
sapiens]
Length = 758
Score = 258 bits (658), Expect = 1e-68
Identities = 144/412 (34%), Positives = 240/412 (58%), Gaps = 7/412 (1%)
Query: 1 MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS 60
++G+AF++A+V + I +++G+ A +HGY VDSNQE++ALG SN G F+ + C++S
Sbjct: 344 LVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMS 403
Query: 61 VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP 120
+L + GG SQVA SL +++ ++ LG + LPK+VL A+I VNLK L+QL+D
Sbjct: 404 RSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDM 463
Query: 121 YYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD 180
LW+ ++ D IW+V+F ++ L+L G+ V V FS+L+VV +TQ + L QV DTD
Sbjct: 464 RSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTD 523
Query: 181 IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQ 240
IY + Y+ A++++G+K+ + +YFAN+E + + + G+D ++ K+K LKKQ
Sbjct: 524 IYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQ 583
Query: 241 EKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSS 300
E+ +++ Q+ L + + + + N D +N N + S D
Sbjct: 584 EQLKLKQLQKEEKLRKQAASPKGASVSINV-NTSLEDMRSN----NVEDCKMMVSSGDKM 638
Query: 301 SPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGK 360
A + ++AP + S + A P FH+LILD+ +SFVD + +K+L + + +
Sbjct: 639 EDATANGQEDSKAP-DGSTLKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFRE 697
Query: 361 IGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQANARDV 412
I V+V++ H+ V + + G F D S+ KH+F S+HDAV FA + R V
Sbjct: 698 IEVEVYMAACHSPVVSQLEAGHFF-DASITKKHLFASVHDAVTFALQHPRPV 748
>gi|39752683 prestin isoform a [Homo sapiens]
Length = 744
Score = 256 bits (655), Expect = 2e-68
Identities = 147/432 (34%), Positives = 237/432 (54%), Gaps = 41/432 (9%)
Query: 5 AFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLA 64
A ++AIV + + ++M +TLANKHGY VD NQE+IALG N GS F+ I C+LS +L
Sbjct: 343 AIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLV 402
Query: 65 VDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYYLW 124
+G GGK+Q+A SL++++ +L G LP++VL A++ VNLK Q +D + W
Sbjct: 403 QEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFW 462
Query: 125 RKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDIYVN 184
R SK++ IW+ +F+SS FL L YG+ V ++L V+++TQ + L ++ +TD+Y++
Sbjct: 463 RTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYID 522
Query: 185 PKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQEKRR 244
Y ++I GIKI +P+Y+ANS+++ + KTG++P ++ A++K ++K K
Sbjct: 523 IDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAK-- 580
Query: 245 MRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSSSPAQ 304
+ + M TV + + D E+A P+
Sbjct: 581 -----EVGNANMANATVVKADAEVDGEDAT---------------------KPEEEDGEV 614
Query: 305 SEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVK 364
PP ++ P +M +PP HT+ILD + V+F+D +G+K LA + YG +G+
Sbjct: 615 KYPPIVIKST-FPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIY 673
Query: 365 VFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQANARDVTPGHNFQGAPGD 424
V+L AQV ND++ FE+ +L + +F SIHDAVL G + A +
Sbjct: 674 VYLAGCSAQVVNDLTRNRFFENPAL-WELLFHSIHDAVL-----------GSQLREALAE 721
Query: 425 AELSLYDSEEDI 436
E S S+ED+
Sbjct: 722 QEASAPPSQEDL 733
>gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo
sapiens]
Length = 740
Score = 250 bits (639), Expect = 2e-66
Identities = 144/412 (34%), Positives = 238/412 (57%), Gaps = 25/412 (6%)
Query: 1 MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS 60
++G+AF++A+V + I +++G+ A +HGY VDSNQE++ALG SN G F+ + C++S
Sbjct: 344 LVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMS 403
Query: 61 VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP 120
+L + GG SQVA SL +++ ++ LG + LPK+VL A+I VNLK L+QL+D
Sbjct: 404 RSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDM 463
Query: 121 YYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD 180
LW+ ++ D IW+V+F ++ L+L G+ V V FS+L+VV +TQ + L QV DTD
Sbjct: 464 RSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTD 523
Query: 181 IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQ 240
IY + Y+ A++++G+K+ + +YFAN+E + + + G+D ++ K+K LKKQ
Sbjct: 524 IYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQ 583
Query: 241 EKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSS 300
E+ +++ Q+ L + + L AP Q ++G D
Sbjct: 584 EQLKLKQLQKEEKLRKQAGPLLSACL------AP-------QQVSSG----------DKM 620
Query: 301 SPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGK 360
A + ++AP + S + A P FH+LILD+ +SFVD + +K+L + + +
Sbjct: 621 EDATANGQEDSKAP-DGSTLKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFRE 679
Query: 361 IGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQANARDV 412
I V+V++ H+ V + + G F D S+ KH+F S+HDAV FA + R V
Sbjct: 680 IEVEVYMAACHSPVVSQLEAGHFF-DASITKKHLFASVHDAVTFALQHPRPV 730
>gi|45827800 prestin isoform b [Homo sapiens]
Length = 685
Score = 232 bits (591), Expect = 6e-61
Identities = 125/368 (33%), Positives = 205/368 (55%), Gaps = 29/368 (7%)
Query: 5 AFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLA 64
A ++AIV + + ++M +TLANKHGY VD NQE+IALG N GS F+ I C+LS +L
Sbjct: 343 AIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLV 402
Query: 65 VDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYYLW 124
+G GGK+Q+A SL++++ +L G LP++VL A++ VNLK Q +D + W
Sbjct: 403 QEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFW 462
Query: 125 RKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDIYVN 184
R SK++ IW+ +F+SS FL L YG+ V ++L V+++TQ + L ++ +TD+Y++
Sbjct: 463 RTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYID 522
Query: 185 PKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQEKRR 244
Y ++I GIKI +P+Y+ANS+++ + KTG++P ++ A++K ++K K
Sbjct: 523 IDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAK-- 580
Query: 245 MRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSSSPAQ 304
+ + M TV + + D E+A P+
Sbjct: 581 -----EVGNANMANATVVKADAEVDGEDAT---------------------KPEEEDGEV 614
Query: 305 SEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVK 364
PP ++ P +M +PP HT+ILD + V+F+D +G+K LA + YG +G+
Sbjct: 615 KYPPIVIKST-FPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIY 673
Query: 365 VFLVNIHA 372
V+L A
Sbjct: 674 VYLAGCSA 681
>gi|4505697 pendrin [Homo sapiens]
Length = 780
Score = 216 bits (551), Expect = 3e-56
Identities = 131/410 (31%), Positives = 211/410 (51%), Gaps = 32/410 (7%)
Query: 1 MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS 60
M+ +FS+A+V+Y I +++G+ A K+ Y +D NQE IA G SN F FF V ALS
Sbjct: 349 MLAASFSIAVVAYAIAVSVGKVYATKYDYTIDGNQEFIAFGISNIFSGFFSCFVATTALS 408
Query: 61 VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP 120
T + GGK+QVA + + +VMI +L LG L PL KSVL A++ NLK QL D
Sbjct: 409 RTAVQESTGGKTQVAGIISAAIVMIAILALGKLLEPLQKSVLAAVVIANLKGMFMQLCDI 468
Query: 121 YYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD 180
LWR++K+D IWV + + S L L G+ G+ F +L VV + QF + L + TD
Sbjct: 469 PRLWRQNKIDAVIWVFTCIVSIILGLDLGLLAGLIFGLLTVVLRVQFPSWNGLGSIPSTD 528
Query: 181 IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQ 240
IY + K Y ++ QG+KI+ + SP+++ N + F++ + + G D +V + K L+K
Sbjct: 529 IYKSTKNYKNIEEPQGVKILRFSSPIFYGNVDGFKKCIKSTVGFDAIRVYNKRLKALRKI 588
Query: 241 EK----RRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFS 296
+K ++R T + + T + E +D E+ D + I
Sbjct: 589 QKLIKSGQLRAT-KNGIISDAVSTNNAFEPDEDIEDLEELDIPTKE----------IEIQ 637
Query: 297 PDSSSPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSS 356
D + SE P P P H+L+LD +SF+D++G+++L +
Sbjct: 638 VDWN----SELPVKVNVPKVP------------IHSLVLDCGAISFLDVVGVRSLRVIVK 681
Query: 357 TYGKIGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQ 406
+ +I V V+ ++ V + G F+D ++ F ++HDA+L+ Q
Sbjct: 682 EFQRIDVNVYFASLQDYVIEKLEQCGFFDD-NIRKDTFFLTVHDAILYLQ 730
>gi|4557535 solute carrier family 26, member 3 [Homo sapiens]
Length = 764
Score = 206 bits (524), Expect = 4e-53
Identities = 129/402 (32%), Positives = 204/402 (50%), Gaps = 23/402 (5%)
Query: 2 IGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSV 61
+G F +A+V++ + ++ + K+ Y +D NQE+IALG N F+ ALS
Sbjct: 340 VGDCFGIAMVAFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSR 399
Query: 62 TLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPY 121
+ + GGK+Q+A L +++V+I +L +G L PL KSVL AL NLK L Q +
Sbjct: 400 SAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIG 459
Query: 122 YLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDI 181
LWRK K DC IW+++F+ + L L G+A VAF +L +VF+TQF LA + T+I
Sbjct: 460 RLWRKDKYDCLIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNI 519
Query: 182 YVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQE 241
Y N K Y + +G+KI SP+YFAN FR+K+I G P ++L + K L+K
Sbjct: 520 YKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFRRKLIDAVGFSPLRILRKRNKALRKIR 579
Query: 242 KRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSSS 301
K Q++ L T + + ++ D N + + + + F D +
Sbjct: 580 K------LQKQGLLQVTPKGFICTVDTIKDSDEELDNNQIEVLDQPINTTDLPFHIDWN- 632
Query: 302 PAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKI 361
+ P + E P ++ H+LILD S VSF+D+ ++ L + + +I
Sbjct: 633 ---DDLPLNIEVPK------------ISLHSLILDFSAVSFLDVSSVRGLKSILQEFIRI 677
Query: 362 GVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVL 403
V V++V ++ F DG ++ F +IHDAVL
Sbjct: 678 KVDVYIVGTDDDFIEKLNRYEFF-DGEVKSSIFFLTIHDAVL 718
>gi|100913030 solute carrier family 26 member 2 [Homo sapiens]
Length = 739
Score = 169 bits (427), Expect = 6e-42
Identities = 109/404 (26%), Positives = 190/404 (47%), Gaps = 67/404 (16%)
Query: 5 AFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLA 64
A +++I+ + I +++ A KHGY V +NQEM A+G N SFF AL+ TL
Sbjct: 386 AIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLV 445
Query: 65 VDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYYLW 124
+ G +Q++ + +LV+++ +LV+ Y L KSVLG + VNL+ +L++ D +W
Sbjct: 446 KESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVITIVNLRGALRKFRDLPKMW 505
Query: 125 RKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDIYVN 184
S++D IW V+ LSS LS G+ VGV FS+ V+ +TQ L V +++++ +
Sbjct: 506 SISRMDTVIWFVTMLSSALLSTEIGLLVGVCFSIFCVILRTQKPKSSLLGLVEESEVFES 565
Query: 185 PKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQEKRR 244
Y Q GIKI + +PLY+ N E F+ + +T ++P + +A +K K++
Sbjct: 566 VSAYKNLQIKPGIKIFRFVAPLYYINKECFKSALYKQT-VNPILIKVAWKKAAKRK---- 620
Query: 245 MRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSSSPAQ 304
+K K V+L +Q + DP
Sbjct: 621 -----------IKEKVVTLGGIQDEMSVQLSHDP-------------------------- 643
Query: 305 SEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVK 364
+ HT+++D S + F+D GI L ++ Y IG++
Sbjct: 644 -----------------------LELHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAIGIQ 680
Query: 365 VFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQAN 408
V L + V + +++G + E +F S+++A+ FA+ +
Sbjct: 681 VLLAQCNPTVRDSLTNGEYCK--KEEENLLFYSVYEAMAFAEVS 722
>gi|16418457 solute carrier family 26, member 8 isoform a [Homo
sapiens]
Length = 970
Score = 166 bits (421), Expect = 3e-41
Identities = 127/473 (26%), Positives = 225/473 (47%), Gaps = 57/473 (12%)
Query: 5 AFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLA 64
AFSL++VS + + +G+ +A+ H Y V+SNQ++IA+G N SFF+ V A++ T+
Sbjct: 361 AFSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTII 420
Query: 65 VDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYYLW 124
D +GG+ Q ASL + V+++ M+ +G + Y LP +VL +I N+ L+ +++ LW
Sbjct: 421 QDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLW 480
Query: 125 RKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDIYVN 184
R+ + DC +W+++F SS FL L G+ + V + + ++ L Q+ +T+IY +
Sbjct: 481 RQDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRS 540
Query: 185 PKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLK------ 238
Y I G+KI CS + F N + K++ + +D KV L +++
Sbjct: 541 INDYREIITIPGVKIFQCCSSITFVNVYYLKHKLLKE--VDMVKVPLKEEEIFSLFNSSD 598
Query: 239 ---------------------------KQEKRRMRPTQQRRSLFMKTKTVSLQELQQDFE 271
++ + ++ P +L + S+ Q E
Sbjct: 599 TNLQGGKICRCFCNCDDLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTSQTASE 658
Query: 272 NAPPTDPNNNQTPANGTSVSYI--TFSPDSSSPAQSEP--PASAEAPGEPSDML---ASV 324
+ P ++ G + + P++SS S P P AE+ G S + AS+
Sbjct: 659 DQVPYTVSSVSQKNQGQQYEEVEEVWLPNNSS-RNSSPGLPDVAESQGRRSLIPYSDASL 717
Query: 325 PPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVKVFLVNIHAQVYNDISHGGVF 384
P V HT+ILD S V +VD G+ L ++ + + + + + H+ + F
Sbjct: 718 LPSV--HTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFF 775
Query: 385 EDGSLECKHVFPSIHDAVLFAQANARDVTPGHNFQGAPGDAELSLYDSEEDIR 437
+ G + + +F S+HDAVLFA + + G +ELS+ +SE IR
Sbjct: 776 DAGITKTQ-LFLSVHDAVLFALS-----------RKVIGSSELSIDESETVIR 816
>gi|20336285 solute carrier family 26, member 8 isoform b [Homo
sapiens]
Length = 865
Score = 166 bits (421), Expect = 3e-41
Identities = 127/473 (26%), Positives = 225/473 (47%), Gaps = 57/473 (12%)
Query: 5 AFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLA 64
AFSL++VS + + +G+ +A+ H Y V+SNQ++IA+G N SFF+ V A++ T+
Sbjct: 256 AFSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTII 315
Query: 65 VDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYYLW 124
D +GG+ Q ASL + V+++ M+ +G + Y LP +VL +I N+ L+ +++ LW
Sbjct: 316 QDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLW 375
Query: 125 RKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDIYVN 184
R+ + DC +W+++F SS FL L G+ + V + + ++ L Q+ +T+IY +
Sbjct: 376 RQDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRS 435
Query: 185 PKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLK------ 238
Y I G+KI CS + F N + K++ + +D KV L +++
Sbjct: 436 INDYREIITIPGVKIFQCCSSITFVNVYYLKHKLLKE--VDMVKVPLKEEEIFSLFNSSD 493
Query: 239 ---------------------------KQEKRRMRPTQQRRSLFMKTKTVSLQELQQDFE 271
++ + ++ P +L + S+ Q E
Sbjct: 494 TNLQGGKICRCFCNCDDLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTSQTASE 553
Query: 272 NAPPTDPNNNQTPANGTSVSYI--TFSPDSSSPAQSEP--PASAEAPGEPSDML---ASV 324
+ P ++ G + + P++SS S P P AE+ G S + AS+
Sbjct: 554 DQVPYTVSSVSQKNQGQQYEEVEEVWLPNNSS-RNSSPGLPDVAESQGRRSLIPYSDASL 612
Query: 325 PPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVKVFLVNIHAQVYNDISHGGVF 384
P V HT+ILD S V +VD G+ L ++ + + + + + H+ + F
Sbjct: 613 LPSV--HTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFF 670
Query: 385 EDGSLECKHVFPSIHDAVLFAQANARDVTPGHNFQGAPGDAELSLYDSEEDIR 437
+ G + + +F S+HDAVLFA + + G +ELS+ +SE IR
Sbjct: 671 DAGITKTQ-LFLSVHDAVLFALS-----------RKVIGSSELSIDESETVIR 711
>gi|45827802 prestin isoform c [Homo sapiens]
Length = 516
Score = 152 bits (385), Expect = 5e-37
Identities = 71/162 (43%), Positives = 107/162 (66%)
Query: 5 AFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLA 64
A ++AIV + + ++M +TLANKHGY VD NQE+IALG N GS F+ I C+LS +L
Sbjct: 343 AIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLV 402
Query: 65 VDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYYLW 124
+G GGK+Q+A SL++++ +L G LP++VL A++ VNLK Q +D + W
Sbjct: 403 QEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFW 462
Query: 125 RKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQ 166
R SK++ IW+ +F+SS FL L YG+ V ++L V+++TQ
Sbjct: 463 RTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQ 504
>gi|47131207 solute carrier family 26, member 1 isoform a [Homo
sapiens]
Length = 701
Score = 127 bits (319), Expect = 2e-29
Identities = 66/221 (29%), Positives = 119/221 (53%)
Query: 5 AFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLA 64
A +LA+V+ ++++ A HGY V +NQE++A+GC N +F AL+ +L
Sbjct: 345 AVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLV 404
Query: 65 VDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYYLW 124
G ++Q++S+ + VV++ +L L + L +SVL +I V+L+ +L+++ D LW
Sbjct: 405 KTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRLW 464
Query: 125 RKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDIYVN 184
R S D +W + + +S G+ GV S+L + +TQ LA++ DT Y +
Sbjct: 465 RMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYED 524
Query: 185 PKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMD 225
+ G+++ + PLY+AN + F Q + + TG+D
Sbjct: 525 ATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLD 565
Score = 62.4 bits (150), Expect = 8e-10
Identities = 36/108 (33%), Positives = 56/108 (51%), Gaps = 3/108 (2%)
Query: 308 PASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVKVFL 367
PA E G S A VP FHT+++D + + F+D G+ L L YG +G+ + L
Sbjct: 587 PAQGEDLGPVSTRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLL 646
Query: 368 VNIHAQVYNDISHGGVFEDG---SLECKHVFPSIHDAVLFAQANARDV 412
V + +S GG +G + E + +F S+HDAV A+A R++
Sbjct: 647 ACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTARARHREL 694
>gi|20336272 solute carrier family 26, member 1 isoform a [Homo
sapiens]
Length = 701
Score = 127 bits (319), Expect = 2e-29
Identities = 66/221 (29%), Positives = 119/221 (53%)
Query: 5 AFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLA 64
A +LA+V+ ++++ A HGY V +NQE++A+GC N +F AL+ +L
Sbjct: 345 AVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLV 404
Query: 65 VDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYYLW 124
G ++Q++S+ + VV++ +L L + L +SVL +I V+L+ +L+++ D LW
Sbjct: 405 KTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRLW 464
Query: 125 RKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDIYVN 184
R S D +W + + +S G+ GV S+L + +TQ LA++ DT Y +
Sbjct: 465 RMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYED 524
Query: 185 PKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMD 225
+ G+++ + PLY+AN + F Q + + TG+D
Sbjct: 525 ATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLD 565
Score = 62.4 bits (150), Expect = 8e-10
Identities = 36/108 (33%), Positives = 56/108 (51%), Gaps = 3/108 (2%)
Query: 308 PASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVKVFL 367
PA E G S A VP FHT+++D + + F+D G+ L L YG +G+ + L
Sbjct: 587 PAQGEDLGPVSTRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLL 646
Query: 368 VNIHAQVYNDISHGGVFEDG---SLECKHVFPSIHDAVLFAQANARDV 412
V + +S GG +G + E + +F S+HDAV A+A R++
Sbjct: 647 ACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTARARHREL 694
>gi|16306483 solute carrier family 26, member 7 isoform a [Homo
sapiens]
Length = 656
Score = 112 bits (281), Expect = 5e-25
Identities = 69/214 (32%), Positives = 111/214 (51%), Gaps = 2/214 (0%)
Query: 1 MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS 60
+I AF +A+V YV +LA+ + A K Y +D NQE +A G SN SFF A+
Sbjct: 308 VITEAFGVALVGYVASLALAQGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAMG 367
Query: 61 VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP 120
T + G K+QVA L + V+I + +G LY LP VL ++I V LK L Q D
Sbjct: 368 RTAGLYSTGAKTQVACLISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDL 427
Query: 121 YYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD 180
W K+D IWV +++ + + G+ GV ++ +V+ + ++ + + +
Sbjct: 428 KKYWNVDKIDWGIWVSTYVFTICFAANVGLLFGVVCTIAIVIGRFPRAMTVSIKNMKEME 487
Query: 181 IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIF 214
V KT ++ +Q +KII+ +PL F N++ F
Sbjct: 488 FKV--KTEMDSETLQQVKIISINNPLVFLNAKKF 519
>gi|20336282 solute carrier family 26, member 7 isoform b [Homo
sapiens]
Length = 663
Score = 112 bits (281), Expect = 5e-25
Identities = 69/214 (32%), Positives = 111/214 (51%), Gaps = 2/214 (0%)
Query: 1 MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS 60
+I AF +A+V YV +LA+ + A K Y +D NQE +A G SN SFF A+
Sbjct: 308 VITEAFGVALVGYVASLALAQGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAMG 367
Query: 61 VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP 120
T + G K+QVA L + V+I + +G LY LP VL ++I V LK L Q D
Sbjct: 368 RTAGLYSTGAKTQVACLISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDL 427
Query: 121 YYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD 180
W K+D IWV +++ + + G+ GV ++ +V+ + ++ + + +
Sbjct: 428 KKYWNVDKIDWGIWVSTYVFTICFAANVGLLFGVVCTIAIVIGRFPRAMTVSIKNMKEME 487
Query: 181 IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIF 214
V KT ++ +Q +KII+ +PL F N++ F
Sbjct: 488 FKV--KTEMDSETLQQVKIISINNPLVFLNAKKF 519
>gi|65506789 solute carrier family 26, member 10 [Homo sapiens]
Length = 563
Score = 80.1 bits (196), Expect = 4e-15
Identities = 43/135 (31%), Positives = 74/135 (54%)
Query: 1 MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS 60
++ + +A+VS+ ++ ++ A+K+ Y +DSNQE +A G SN S F L+
Sbjct: 279 ILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLISSLFSCFPNSATLA 338
Query: 61 VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP 120
T + AGGK+Q+A L VV+ +L LG + Y LPK+VL + +++ Q+ +
Sbjct: 339 TTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSMRQVFCQMQEL 398
Query: 121 YYLWRKSKLDCCIWV 135
LW S++D + V
Sbjct: 399 PQLWHISRVDFLLQV 413
Score = 30.0 bits (66), Expect = 4.6
Identities = 19/77 (24%), Positives = 38/77 (49%), Gaps = 6/77 (7%)
Query: 333 LILDMSGVSFVDLMG----IKALAKLSSTYGKIGVKVFLVNIHAQVYNDISHGGVFEDGS 388
++LD SGV+F D G ++ +L+S +++ L +A V ++ G+ +
Sbjct: 467 VVLDFSGVTFADAAGAREVVQVRERLASRCRDARIRLLLAQCNALVQGTLTRVGLLD--R 524
Query: 389 LECKHVFPSIHDAVLFA 405
+ +F S+ DA +A
Sbjct: 525 VTPDQLFVSVQDAAAYA 541
>gi|85540447 solute carrier family 26, member 11 [Homo sapiens]
Length = 606
Score = 63.2 bits (152), Expect = 5e-10
Identities = 40/150 (26%), Positives = 78/150 (52%), Gaps = 8/150 (5%)
Query: 16 NLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVA 75
++A+ + A+++ Y +D+NQE++A+G +N GS + + + T +G +
Sbjct: 321 SIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAG 380
Query: 76 SLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYY---LWRKSKLDCC 132
L ++V++++ L Y +PKS L A+I + ++ L D LWR +LD
Sbjct: 381 GLVTGVLVLLSLDYLTSLFYYIPKSALAAVIIM----AVAPLFDTKIFRTLWRVKRLDLL 436
Query: 133 IWVVSFLSSFFLSLPYGVAVGVAFSVLVVV 162
V+FL F+ + YG+ G S+L+++
Sbjct: 437 PLCVTFLLCFW-EVQYGILAGALVSLLMLL 465
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 35.4 bits (80), Expect = 0.11
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 9/102 (8%)
Query: 233 KQKYLKKQEKRRMRPTQ--QRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSV 290
K K ++Q + R++ Q +RR M T+ V Q L P T TP
Sbjct: 1809 KHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPP 1868
Query: 291 SYITFSPDSSSP------AQSEPPASAEAPGEPSDMLASVPP 326
+ SP S SP A+++PP + + G+P+ + + PP
Sbjct: 1869 AQPQPSPVSMSPAGFPSVARTQPPTTV-STGKPTSQVPAPPP 1909
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 35.4 bits (80), Expect = 0.11
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 9/102 (8%)
Query: 233 KQKYLKKQEKRRMRPTQ--QRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSV 290
K K ++Q + R++ Q +RR M T+ V Q L P T TP
Sbjct: 1847 KHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPP 1906
Query: 291 SYITFSPDSSSP------AQSEPPASAEAPGEPSDMLASVPP 326
+ SP S SP A+++PP + + G+P+ + + PP
Sbjct: 1907 AQPQPSPVSMSPAGFPSVARTQPPTTV-STGKPTSQVPAPPP 1947
>gi|150170729 microtubule associated serine/threonine kinase 3 [Homo
sapiens]
Length = 1309
Score = 33.9 bits (76), Expect = 0.32
Identities = 30/108 (27%), Positives = 50/108 (46%), Gaps = 20/108 (18%)
Query: 226 PQKVLLAKQKYLKKQEKRRMRPTQQRR-SLFMK-TKTVSLQELQQDFEN----------A 273
P + +AK + ++ ++ R R TQ RR SLF K +K S+ + F + +
Sbjct: 1046 PARKNVAKGRMARRSKRSRRRETQDRRKSLFKKISKQTSVLHTSRSFSSGLHHSLSSSES 1105
Query: 274 PPTDPNNNQTPANGTSV--------SYITFSPDSSSPAQSEPPASAEA 313
P P ++ +P+ T + T SP S+SP+ S P + A A
Sbjct: 1106 LPGSPTHSLSPSPTTPCRSPAPDVPADTTASPPSASPSSSSPASPAAA 1153
>gi|50054477 olfactory receptor, family 5, subfamily AS, member 1
[Homo sapiens]
Length = 324
Score = 33.9 bits (76), Expect = 0.32
Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 5/72 (6%)
Query: 30 DVDSNQEMIALGCSNFFGSFFKIHVIC--CALSVTLAVDGAGGKSQVASLCVSLVVMITM 87
D NQ ++ CS S F + I C L L++ +GG+S+ S C S ++ +T+
Sbjct: 191 DTQINQLLLFALCSFIQTSTFVVIFISYFCILITVLSIKSSGGRSKTFSTCASHLIAVTL 250
Query: 88 L---VLGIYLYP 96
+L +YL P
Sbjct: 251 FYGALLFMYLQP 262
>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
sapiens]
Length = 1907
Score = 33.5 bits (75), Expect = 0.41
Identities = 21/92 (22%), Positives = 35/92 (38%), Gaps = 6/92 (6%)
Query: 232 AKQKYLKKQEKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAP------PTDPNNNQTPA 285
A + +LK + R ++R + ++ K + L + + P P PN P
Sbjct: 1598 AHENWLKARAAERAIAEEKREAANLRHKLLELTQKMAMLQEEPVIVKPMPGKPNTQNPPR 1657
Query: 286 NGTSVSYITFSPDSSSPAQSEPPASAEAPGEP 317
G +F P S + PP + E P P
Sbjct: 1658 RGPLSQNGSFGPSPVSGGECSPPLTVEPPVRP 1689
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 33.5 bits (75), Expect = 0.41
Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 2/65 (3%)
Query: 261 VSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSSSPAQSEPPASAEAPGEPSDM 320
+ LQ+ QQ + PP N + PA + S P +P Q PPAS + P P+
Sbjct: 184 LQLQQQQQQQQQQPPPSTNQHPQPAP-QAPSQSQQQPLQPTPPQQPPPASQQPPA-PTSQ 241
Query: 321 LASVP 325
L P
Sbjct: 242 LQQAP 246
>gi|226498466 T-cell immunoglobulin and mucin domain containing 4
isoform 2 [Homo sapiens]
Length = 350
Score = 33.1 bits (74), Expect = 0.54
Identities = 26/123 (21%), Positives = 49/123 (39%), Gaps = 1/123 (0%)
Query: 266 LQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSSSPAQSEPPASAEAPGEPSDMLASVP 325
L + E P+D ++ + +V + + D++ P Q++ + + G P M +P
Sbjct: 224 LTAESETVLPSDSWSSVESTSADTVLLTSKASDTAVPEQNKTTKTGQMDGIPMSMKNEMP 283
Query: 326 PFVTFHTLILDMSGVSFVDLMGIKALAKLSSTY-GKIGVKVFLVNIHAQVYNDISHGGVF 384
+ + V F + KL TY + ++ + V ND+ HG
Sbjct: 284 ISQLLMIIAPSLGFVLFALFVAFLLRGKLMETYCSQKHTRLDYIGDSKNVLNDVQHGRED 343
Query: 385 EDG 387
EDG
Sbjct: 344 EDG 346
>gi|24233580 synaptonemal complex protein 3 [Homo sapiens]
Length = 236
Score = 33.1 bits (74), Expect = 0.54
Identities = 17/55 (30%), Positives = 30/55 (54%)
Query: 216 QKVIAKTGMDPQKVLLAKQKYLKKQEKRRMRPTQQRRSLFMKTKTVSLQELQQDF 270
Q ++ G+D K LLAK+K L+ K ++ + Q+ KT+ Q+L Q++
Sbjct: 71 QNMLEGVGVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQKLNQEY 125
>gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precursor
[Homo sapiens]
Length = 554
Score = 32.7 bits (73), Expect = 0.71
Identities = 52/226 (23%), Positives = 91/226 (40%), Gaps = 28/226 (12%)
Query: 99 KSVLGALIAVNLKNSLKQLTDPYYLWRKSKLDCCIWVVSFLSSFFL---SLPYGVAVGVA 155
KS+ G I + + L++ Y ++ + C + V+ SF++ S+P G+
Sbjct: 237 KSITGEYIVMTVYFHLRRKMG--YFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGIT 294
Query: 156 FSVLVVVFQTQFRNGY---ALAQVMDTDIYVNPKTYNRAQDIQGIKIITYCSPLYFANSE 212
+ + R+ + A MD I V A +I + + YF N +
Sbjct: 295 TVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSA-------LIEFAAVNYFTNIQ 347
Query: 213 IFRQKVIAKTGMDPQKVLLAKQKYLKKQEKRRMRPTQQRRS-LFMKTKTVSLQELQQDFE 271
+ +K KT PQ+V A + +EK P Q + L M+ +T +L + D
Sbjct: 348 M--EKAKRKTSKPPQEVPAAPVQ----REKHPEAPLQNTNANLNMRKRTNALVHSESDVG 401
Query: 272 NAPPTDPNNN------QTPANGTSVSYITFSPDSSSPAQSEPPASA 311
N +++ Q + GT SY+ SP+ S A + SA
Sbjct: 402 NRTEVGNHSSKSSTVVQESSKGTPRSYLASSPNPFSRANAAETISA 447
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,936,264
Number of Sequences: 37866
Number of extensions: 765222
Number of successful extensions: 4220
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 4069
Number of HSP's gapped (non-prelim): 150
length of query: 459
length of database: 18,247,518
effective HSP length: 106
effective length of query: 353
effective length of database: 14,233,722
effective search space: 5024503866
effective search space used: 5024503866
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.