BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21361937 proline rich 7 (synaptic) [Homo sapiens] (274 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21361937 proline rich 7 (synaptic) [Homo sapiens] 592 e-169 gi|239745032 PREDICTED: hypothetical protein XP_002343336 [Homo ... 59 5e-09 gi|239753972 PREDICTED: hypothetical protein [Homo sapiens] 57 2e-08 gi|83977459 pleckstrin homology-like domain, family A, member 1 ... 56 4e-08 gi|23308699 transcription factor MAFB [Homo sapiens] 53 3e-07 gi|239755199 PREDICTED: hypothetical protein [Homo sapiens] 53 3e-07 gi|61966923 forkhead box B2 [Homo sapiens] 53 3e-07 gi|151301053 RNA binding motif protein 33 [Homo sapiens] 51 1e-06 gi|59938776 cAMP responsive element binding protein 5 isoform de... 50 3e-06 gi|59938774 cAMP responsive element binding protein 5 isoform be... 50 3e-06 gi|59938772 cAMP responsive element binding protein 5 isoform ga... 50 3e-06 gi|59938770 cAMP responsive element binding protein 5 isoform al... 50 3e-06 gi|37595553 ring finger protein 111 [Homo sapiens] 49 6e-06 gi|239751592 PREDICTED: hypothetical protein XP_002347924 [Homo ... 48 1e-05 gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 48 1e-05 gi|239757043 PREDICTED: functional smad suppressing element 18 [... 47 1e-05 gi|239751555 PREDICTED: functional smad suppressing element 18 [... 47 1e-05 gi|239746067 PREDICTED: functional smad suppressing element 18 [... 47 1e-05 gi|239746716 PREDICTED: hypothetical protein XP_002343819 [Homo ... 47 2e-05 gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 46 3e-05 gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 46 3e-05 gi|157277988 phosphodiesterase 4D isoform 1 [Homo sapiens] 45 5e-05 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 45 7e-05 gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 45 7e-05 gi|18959210 WIRE protein [Homo sapiens] 45 7e-05 gi|12751477 forkhead box L2 [Homo sapiens] 44 2e-04 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 44 2e-04 gi|148762982 hypothetical protein LOC387640 [Homo sapiens] 44 2e-04 gi|50345831 forkhead box J3 [Homo sapiens] 44 2e-04 gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 44 2e-04 >gi|21361937 proline rich 7 (synaptic) [Homo sapiens] Length = 274 Score = 592 bits (1526), Expect = e-169 Identities = 274/274 (100%), Positives = 274/274 (100%) Query: 1 MVMSQGTYTFLTCFAGFWLIWGLIVLLCCFCSFLRRRLKRRQEERLREQNLRALELEPLE 60 MVMSQGTYTFLTCFAGFWLIWGLIVLLCCFCSFLRRRLKRRQEERLREQNLRALELEPLE Sbjct: 1 MVMSQGTYTFLTCFAGFWLIWGLIVLLCCFCSFLRRRLKRRQEERLREQNLRALELEPLE 60 Query: 61 LEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHH 120 LEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHH Sbjct: 61 LEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHH 120 Query: 121 ALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKI 180 ALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKI Sbjct: 121 ALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKI 180 Query: 181 VTPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRPAPPCPALCLQADRGRRVF 240 VTPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRPAPPCPALCLQADRGRRVF Sbjct: 181 VTPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRPAPPCPALCLQADRGRRVF 240 Query: 241 PSWTDSELSSREPLEHGAWRLPVSIPLFGRTTAV 274 PSWTDSELSSREPLEHGAWRLPVSIPLFGRTTAV Sbjct: 241 PSWTDSELSSREPLEHGAWRLPVSIPLFGRTTAV 274 >gi|239745032 PREDICTED: hypothetical protein XP_002343336 [Homo sapiens] Length = 828 Score = 58.9 bits (141), Expect = 5e-09 Identities = 54/173 (31%), Positives = 68/173 (39%), Gaps = 26/173 (15%) Query: 65 LAGSPPGLAPPQPPPHRSRLEAPAHAHS-HPHVH--VHPLLH---HGPAQPHAHAHP--H 116 LA SPPG PP H P H+ S HP +H HP +H H P P H HP H Sbjct: 11 LAVSPPGKICIHPPLH-----PPTHSPSIHPSIHPPTHPSIHPSIHPPTHPSIHTHPPIH 65 Query: 117 PHHHALPHPPPTHLSVPP--RPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTR 174 PH H P PPTH S+ P P +P S P ++ + PP +S + Sbjct: 66 PHTHP-PIHPPTHPSIHPLIHPSIHP-------SLHPPTHSSIHPSTHPPTHSSIHPSIH 117 Query: 175 GLYRKIVTPFL--SRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRPAPP 225 ++ P + S S PS PL + H P P PP Sbjct: 118 PSTHPLIHPSIHPSTHSSIHPPTHSHPSTHPL-IHPSIHPPTHSPIHPSIHPP 169 Score = 46.2 bits (108), Expect = 3e-05 Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 6/76 (7%) Query: 70 PGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLH---HGPAQPHAHAHPHPHHHALPHPP 126 P + P P S + P H+H H +HP +H H P P H HP H H Sbjct: 122 PLIHPSIHPSTHSSIHPPTHSHPSTHPLIHPSIHPPTHSPIHPSIHPPTHPPTHPSIHSS 181 Query: 127 ---PTHLSVPPRPWSY 139 PTH S+ P S+ Sbjct: 182 IHLPTHSSIHPPTHSF 197 Score = 33.9 bits (76), Expect = 0.16 Identities = 31/111 (27%), Positives = 39/111 (35%), Gaps = 23/111 (20%) Query: 70 PGLAPP-QPPPH-----------RSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHP 117 P + PP PP H S + P H+ HP +H H P P H HP Sbjct: 164 PSIHPPTHPPTHPSIHSSIHLPTHSSIHPPTHSFIHPSIHPPT---HSPIHPLTHPFIHP 220 Query: 118 HHHALPHPP------PTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEP 162 + T +S PRP P A + S PP + V A P Sbjct: 221 SDSSAASAGGVGPALQTRMSGHPRPTGSPVLALA--SHPPWHSLEVYRALP 269 >gi|239753972 PREDICTED: hypothetical protein [Homo sapiens] Length = 298 Score = 56.6 bits (135), Expect = 2e-08 Identities = 46/164 (28%), Positives = 59/164 (35%), Gaps = 14/164 (8%) Query: 70 PGLAPPQPPPHRSRLEAPAHAHSHPHVH--VHPLLHHGPAQPHAHA--HP--HPHHHALP 123 P + P PP P H +HP +H HP + P P AH HP HP H Sbjct: 83 PPIHPSTNPPIHPSTNPPIHPSTHPTIHPSTHPPSTYLPIHPSAHPLIHPFIHPLTHLFI 142 Query: 124 HPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTP 183 HPPPTH + P S PP Y + PP P+ + ++ P Sbjct: 143 HPPPTHSPIHPPTHSSIHLPTHLSIYPPTYPS---IHPPPTPHPSIHPPIHPSTHPLIHP 199 Query: 184 FLSRRDSAEKQEQPP--PSYKPLFLDRGYTSALHLPSAPRPAPP 225 S S PP P P + +H P+ P PP Sbjct: 200 --STHTSTHPPTHPPTHPPSNP-SIHSSIHPPIHPPTHPSTHPP 240 Score = 46.2 bits (108), Expect = 3e-05 Identities = 43/166 (25%), Positives = 60/166 (36%), Gaps = 18/166 (10%) Query: 70 PGLAPPQPPPHRSRLEAPAHAHSHPHVH--VHPLLHHGPAQPHAHAHPHPHHHALPHPPP 127 P + P P P H +HP +H +P +H P H HP H HPP Sbjct: 59 PPIHPSTHLPIHPSTHLPIHPSTHPPIHPSTNPPIHPS-TNPPIHPSTHPTIHPSTHPPS 117 Query: 128 THLSVPP------RPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIV 181 T+L + P P+ +P + PP + PP +S + T Sbjct: 118 TYLPIHPSAHPLIHPFIHP-LTHLFIHPPPTHSPI-----HPPTHSSIHLPTHLSIYPPT 171 Query: 182 TPFLSRRDSAEKQEQPP--PSYKPLFLDRGYTSALHLPSAPRPAPP 225 P + + PP PS PL +TS H P+ P PP Sbjct: 172 YPSIHPPPTPHPSIHPPIHPSTHPLIHPSTHTST-HPPTHPPTHPP 216 Score = 44.3 bits (103), Expect = 1e-04 Identities = 35/106 (33%), Positives = 40/106 (37%), Gaps = 20/106 (18%) Query: 69 PPGLAPPQPPPHRSRLEAPAHAHSHPHVH--VHPLLHHGPAQPHAHAHP--HPHHHALPH 124 PP P PP S + P H +P + +HP P PH HP HP H L H Sbjct: 144 PPPTHSPIHPPTHSSIHLPTHLSIYPPTYPSIHP-----PPTPHPSIHPPIHPSTHPLIH 198 Query: 125 P-------PPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPP 163 P PPTH P P S P S PP + PP Sbjct: 199 PSTHTSTHPPTH--PPTHPPSNPSIHSS--IHPPIHPPTHPSTHPP 240 Score = 39.7 bits (91), Expect = 0.003 Identities = 32/131 (24%), Positives = 45/131 (34%), Gaps = 9/131 (6%) Query: 95 HVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYE 154 H +HP H P P H HP H LP P TH + P + + P + Sbjct: 49 HPTIHPSSTHPPIHPSTHLPIHPSTH-LPIHPSTHPPIHPSTNPPIHPSTNPPIHPSTHP 107 Query: 155 EAVLMAEPPPPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSAL 214 PP Y + L + P PPP++ P+ S++ Sbjct: 108 TIHPSTHPPSTYLPIHPSAHPLIHPFIHPL------THLFIHPPPTHSPIHPPT--HSSI 159 Query: 215 HLPSAPRPAPP 225 HLP+ PP Sbjct: 160 HLPTHLSIYPP 170 Score = 39.7 bits (91), Expect = 0.003 Identities = 26/86 (30%), Positives = 32/86 (37%), Gaps = 23/86 (26%) Query: 70 PGLAPPQPPPHRSRLEAPAHAHSHPHVH----------VHPLLH-----------HGPAQ 108 P + PP P PH S + P H +HP +H HP H H P Sbjct: 173 PSIHPP-PTPHPS-IHPPIHPSTHPLIHPSTHTSTHPPTHPPTHPPSNPSIHSSIHPPIH 230 Query: 109 PHAHAHPHPHHHALPHPPPTHLSVPP 134 P H HP H+ HP + PP Sbjct: 231 PPTHPSTHPPIHSSTHPSTYFSTHPP 256 Score = 34.7 bits (78), Expect = 0.092 Identities = 25/84 (29%), Positives = 32/84 (38%), Gaps = 10/84 (11%) Query: 58 PLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHP 117 PL + + P PP PP + + H HP HP H P H+ HP Sbjct: 195 PLIHPSTHTSTHPPTHPPTHPPSNPSIHSSIHPPIHP--PTHPSTH-----PPIHSSTHP 247 Query: 118 HHHALPHPP---PTHLSVPPRPWS 138 + HPP P L RP+S Sbjct: 248 STYFSTHPPLLSPKVLQKAFRPFS 271 >gi|83977459 pleckstrin homology-like domain, family A, member 1 [Homo sapiens] Length = 401 Score = 55.8 bits (133), Expect = 4e-08 Identities = 30/94 (31%), Positives = 40/94 (42%), Gaps = 1/94 (1%) Query: 40 RRQEERLREQNLRALELEPLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVH 99 R++++ L +Q + +L+ P PQ P P HP+ H H Sbjct: 296 RQKQQHLVQQQPPSQPQPQPQLQPQPQPQPQPQPQPQSQPQPQPQPKPQPQQLHPYPHPH 355 Query: 100 PLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVP 133 P H P H H HPHPH H +PHP P S P Sbjct: 356 PHPHSHP-HSHPHPHPHPHPHQIPHPHPQPHSQP 388 Score = 52.4 bits (124), Expect = 4e-07 Identities = 23/51 (45%), Positives = 25/51 (49%), Gaps = 1/51 (1%) Query: 75 PQPPPHRSRLEAPAHAHSHPHVHVHPLLH-HGPAQPHAHAHPHPHHHALPH 124 PQP P +L H H HPH H H H H PH HPHP H+ PH Sbjct: 339 PQPKPQPQQLHPYPHPHPHPHSHPHSHPHPHPHPHPHQIPHPHPQPHSQPH 389 Score = 47.0 bits (110), Expect = 2e-05 Identities = 24/74 (32%), Positives = 30/74 (40%), Gaps = 3/74 (4%) Query: 70 PGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTH 129 P L P P + + + + P P H PH H H HPH H PHP P Sbjct: 315 PQLQPQPQPQPQPQPQPQSQPQPQPQPKPQPQQLHPYPHPHPHPHSHPHSHPHPHPHPHP 374 Query: 130 LSVP---PRPWSYP 140 +P P+P S P Sbjct: 375 HQIPHPHPQPHSQP 388 Score = 46.2 bits (108), Expect = 3e-05 Identities = 22/48 (45%), Positives = 23/48 (47%), Gaps = 8/48 (16%) Query: 75 PQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHAL 122 P P PH +H HSHPH H HP H P PH H PH H L Sbjct: 354 PHPHPH-------SHPHSHPHPHPHPHPHQIP-HPHPQPHSQPHGHRL 393 Score = 28.9 bits (63), Expect = 5.1 Identities = 22/94 (23%), Positives = 32/94 (34%), Gaps = 4/94 (4%) Query: 76 QPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPR 135 Q H + + P+ P + P P QP + P P P P P L P Sbjct: 297 QKQQHLVQQQPPSQPQPQPQLQPQPQPQPQP-QPQPQSQPQPQPQ--PKPQPQQLHPYPH 353 Query: 136 PWSYPRQAESDMSKPPCYEEAVLMAEP-PPPYSE 168 P +P P + + P P P+S+ Sbjct: 354 PHPHPHSHPHSHPHPHPHPHPHQIPHPHPQPHSQ 387 >gi|23308699 transcription factor MAFB [Homo sapiens] Length = 323 Score = 52.8 bits (125), Expect = 3e-07 Identities = 33/99 (33%), Positives = 39/99 (39%), Gaps = 8/99 (8%) Query: 47 REQNLRALELEPLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPL----- 101 ++ N AL L P + +L GS P PQP H H H H H H Sbjct: 93 QQMNPEALNLTPEDAVEALIGSHP---VPQPLQSFDSFRGAHHHHHHHHPHPHHAYPGAG 149 Query: 102 LHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSYP 140 + H PHAH H H HH A P P P S+P Sbjct: 150 VAHDELGPHAHPHHHHHHQASPPPSSAASPAQQLPTSHP 188 >gi|239755199 PREDICTED: hypothetical protein [Homo sapiens] Length = 279 Score = 52.8 bits (125), Expect = 3e-07 Identities = 37/127 (29%), Positives = 45/127 (35%), Gaps = 21/127 (16%) Query: 70 PGLAPPQPPP---------HRSRLEAPAHAHSHPHVH--VHPLLH-------HGPAQPHA 111 P + PP P H P H +HP +H +HP H H P P Sbjct: 141 PSIHPPTHPSIHASTHPLIHHPSTHPPTHPSTHPSIHPTIHPRAHPPIHPSIHSPTHPSI 200 Query: 112 HAHPHPHHHALPHP---PPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSE 168 H HP H L HP P H ++ P + PR S S C + P Sbjct: 201 HPSTHPSTHPLTHPSTYPSIHPTIHPLTYPLPRANASVDSHLQCGRSSEERKVNPARVRF 260 Query: 169 VLTDTRG 175 VLT T G Sbjct: 261 VLTSTLG 267 Score = 49.3 bits (116), Expect = 4e-06 Identities = 31/90 (34%), Positives = 38/90 (42%), Gaps = 8/90 (8%) Query: 58 PLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVH--VHPLLH---HGPAQPHAH 112 P+ EG L G+ P P P H HP +H +HP +H H P +P H Sbjct: 33 PVSGEGLLGQGAEGIGPSIHPSIHPSTHPPIHPSIHPSIHPSIHPPVHPSIHPPTRPSIH 92 Query: 113 AHPHPHHHALPHPPPTHLSVPP--RPWSYP 140 HP H H P TH S+ P P YP Sbjct: 93 PSIHPPVHLSTH-PSTHPSIHPPIHPSIYP 121 Score = 48.1 bits (113), Expect = 8e-06 Identities = 26/74 (35%), Positives = 32/74 (43%), Gaps = 7/74 (9%) Query: 74 PPQPPPHRSRLEAPAHAHSHPHVHV--HPLLHHGPAQPHAHAHPHPHHHALPHP---PPT 128 P PP + H +HP +H HPL+HH P H HP H HP PP Sbjct: 129 PSIHPPIHPFIHPSIHPPTHPSIHASTHPLIHHPSTHPPTHPSTHPSIHPTIHPRAHPPI 188 Query: 129 HLSV--PPRPWSYP 140 H S+ P P +P Sbjct: 189 HPSIHSPTHPSIHP 202 Score = 43.1 bits (100), Expect = 3e-04 Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 10/72 (13%) Query: 70 PGLAPPQPPPHRSRLEAPAHAHSHPHVH--VHPLLH-------HGPAQPHAHAHPHPHHH 120 P + PP P + P H +HP H +HP +H H P H HP H Sbjct: 81 PSIHPPTRPSIHPSIHPPVHLSTHPSTHPSIHPPIHPSIYPSIHLSTHPSIHPPIHPFIH 140 Query: 121 ALPHPPPTHLSV 132 H PPTH S+ Sbjct: 141 PSIH-PPTHPSI 151 >gi|61966923 forkhead box B2 [Homo sapiens] Length = 432 Score = 52.8 bits (125), Expect = 3e-07 Identities = 40/132 (30%), Positives = 47/132 (35%), Gaps = 29/132 (21%) Query: 32 SFLRRRLKRRQEERLREQNLRALELEPLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAH 91 SFLRRR + + L + L S PG P H H Sbjct: 101 SFLRRR-----------KRFKVLRADHTHLHAGSTKSAPGAGPG------------GHLH 137 Query: 92 SHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPP 151 H H H H HH HA AH H HHH P PPP PP Y Q +PP Sbjct: 138 PHHHHHPHHHHHH-----HAAAHHHHHHHP-PQPPPPPPPPPPHMVHYFHQQPPTAPQPP 191 Query: 152 CYEEAVLMAEPP 163 + + +PP Sbjct: 192 PHLPSQPPQQPP 203 >gi|151301053 RNA binding motif protein 33 [Homo sapiens] Length = 1170 Score = 51.2 bits (121), Expect = 1e-06 Identities = 32/94 (34%), Positives = 41/94 (43%), Gaps = 13/94 (13%) Query: 72 LAPPQPPPHRSRLEAPAHA----HSHPHVHVH-------PLLHHGPAQPHAHAHPHPHHH 120 L PP PPPH+ + + P H PH H P H P P H H H HHH Sbjct: 582 LHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHH 641 Query: 121 -ALPHPPPTHLSVPP-RPWSYPRQAESDMSKPPC 152 ++P PP +S P RP Q ++ S+ C Sbjct: 642 LSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQC 675 Score = 38.5 bits (88), Expect = 0.006 Identities = 29/101 (28%), Positives = 38/101 (37%), Gaps = 9/101 (8%) Query: 70 PGLAPPQPPP--HRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHP-- 125 P L PP P H S+ P A + P + GP QP H P+ HP Sbjct: 530 PALQPPGPVGILHFSQ---PGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPL 586 Query: 126 PPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPY 166 PP H P +P P +PP + +PPP + Sbjct: 587 PPPHQPQPQQPQQQPPPQHQPPHQPP--HQPPPQHQPPPQH 625 Score = 32.0 bits (71), Expect = 0.60 Identities = 51/207 (24%), Positives = 65/207 (31%), Gaps = 60/207 (28%) Query: 63 GSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVH-VHPLLHHGPAQPHAHAHPHPHHHA 121 G + P L P QPP +AP P + L P QP HPHH Sbjct: 299 GRMKDHRPALLPTQPPVVP---QAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQ-HPHH-- 352 Query: 122 LPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIV 181 P PP M PP E +M PPP V Sbjct: 353 -PSPP------------------QGMHMPPQLETPRMMMTPPP----------------V 377 Query: 182 TPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRPAPPCPALCLQADRGRRVFP 241 TP +QP + + + +P P P+ P PA+ Q G FP Sbjct: 378 TP-----------QQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFP 426 Query: 242 SWTDSELSS------REPLEHGAWRLP 262 T + + R PL+ WR P Sbjct: 427 QHTPGPVPNSFSQPPRLPLQ-DQWRAP 452 Score = 32.0 bits (71), Expect = 0.60 Identities = 42/171 (24%), Positives = 61/171 (35%), Gaps = 39/171 (22%) Query: 69 PPGLAPPQ----PPPHRSRLEAPAHAHSHPHVH------VHPLLHHGPAQPHAHAHPH-- 116 PP L P+ PPP + P + H +PH V L P+QP P Sbjct: 362 PPQLETPRMMMTPPPVTP--QQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRF 419 Query: 117 ------PHHHALPHPPPTHLSVPPR-----PWSYPRQAES------DMSKPPCYEEAVLM 159 P H P P P S PPR W P + +S P + + + Sbjct: 420 PGPPEFPQH--TPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFL 477 Query: 160 AE----PPPPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPP--PSYKPL 204 + PPPP +L + + + PF + +Q Q P P +P+ Sbjct: 478 EQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPV 528 Score = 32.0 bits (71), Expect = 0.60 Identities = 35/130 (26%), Positives = 47/130 (36%), Gaps = 16/130 (12%) Query: 47 REQNLRALELEPLELEGSLAGSPPGLAPPQP--PPHRSRLEAPAHAH--SHPHVHVHPLL 102 RE+ +R L+P G L S PG A +P PP + L P +H ++ L Sbjct: 524 RERPVRPA-LQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPL 582 Query: 103 HHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPP-------CYEE 155 H PH P PPP H P P Q + PP + Sbjct: 583 HPPLPPPHQPQPQQPQQQ----PPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHH 638 Query: 156 AVLMAEPPPP 165 ++ PPPP Sbjct: 639 HHHLSVPPPP 648 >gi|59938776 cAMP responsive element binding protein 5 isoform delta [Homo sapiens] Length = 369 Score = 49.7 bits (117), Expect = 3e-06 Identities = 36/135 (26%), Positives = 53/135 (39%), Gaps = 23/135 (17%) Query: 79 PHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWS 138 PH+ + P H H +PH H HP H P H HPH H H+ H P H P P Sbjct: 139 PHQHQT-LPPH-HPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPL 196 Query: 139 YPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPP 198 + ++ +S + +PP P T G R++V ++ P Sbjct: 197 HTGN-QAQVSPATQQMQPTQTIQPPQP-------TGGRRRRVV-------------DEDP 235 Query: 199 PSYKPLFLDRGYTSA 213 + FL+R +A Sbjct: 236 DERRRKFLERNRAAA 250 Score = 49.7 bits (117), Expect = 3e-06 Identities = 29/81 (35%), Positives = 31/81 (38%), Gaps = 26/81 (32%) Query: 78 PPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPH----AHAHPHP-HHHALPHPP------ 126 PPH H H HP H HP HH PH +H H HP HH PHPP Sbjct: 146 PPHHPY----PHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHTGNQ 201 Query: 127 -----------PTHLSVPPRP 136 PT PP+P Sbjct: 202 AQVSPATQQMQPTQTIQPPQP 222 Score = 47.8 bits (112), Expect = 1e-05 Identities = 24/58 (41%), Positives = 27/58 (46%), Gaps = 4/58 (6%) Query: 82 SRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSY 139 SR + H H H H H H L P P+ H H HP HH PHP P H P S+ Sbjct: 125 SRQDQTPHHHMHSHPHQHQTL--PPHHPYPHQHQHPAHH--PHPQPHHQQNHPHHHSH 178 Score = 32.7 bits (73), Expect = 0.35 Identities = 17/53 (32%), Positives = 22/53 (41%), Gaps = 1/53 (1%) Query: 110 HAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEP 162 H H+HPH H PH P H P +P Q + P + + L A P Sbjct: 134 HMHSHPHQHQTLPPHHPYPHQHQHPAHHPHP-QPHHQQNHPHHHSHSHLHAHP 185 >gi|59938774 cAMP responsive element binding protein 5 isoform beta [Homo sapiens] Length = 501 Score = 49.7 bits (117), Expect = 3e-06 Identities = 36/135 (26%), Positives = 53/135 (39%), Gaps = 23/135 (17%) Query: 79 PHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWS 138 PH+ + P H H +PH H HP H P H HPH H H+ H P H P P Sbjct: 271 PHQHQT-LPPH-HPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPL 328 Query: 139 YPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPP 198 + ++ +S + +PP P T G R++V ++ P Sbjct: 329 HTGN-QAQVSPATQQMQPTQTIQPPQP-------TGGRRRRVV-------------DEDP 367 Query: 199 PSYKPLFLDRGYTSA 213 + FL+R +A Sbjct: 368 DERRRKFLERNRAAA 382 Score = 49.7 bits (117), Expect = 3e-06 Identities = 29/81 (35%), Positives = 31/81 (38%), Gaps = 26/81 (32%) Query: 78 PPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPH----AHAHPHP-HHHALPHPP------ 126 PPH H H HP H HP HH PH +H H HP HH PHPP Sbjct: 278 PPHHPY----PHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHTGNQ 333 Query: 127 -----------PTHLSVPPRP 136 PT PP+P Sbjct: 334 AQVSPATQQMQPTQTIQPPQP 354 Score = 47.8 bits (112), Expect = 1e-05 Identities = 24/58 (41%), Positives = 27/58 (46%), Gaps = 4/58 (6%) Query: 82 SRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSY 139 SR + H H H H H H L P P+ H H HP HH PHP P H P S+ Sbjct: 257 SRQDQTPHHHMHSHPHQHQTL--PPHHPYPHQHQHPAHH--PHPQPHHQQNHPHHHSH 310 Score = 32.7 bits (73), Expect = 0.35 Identities = 17/53 (32%), Positives = 22/53 (41%), Gaps = 1/53 (1%) Query: 110 HAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEP 162 H H+HPH H PH P H P +P Q + P + + L A P Sbjct: 266 HMHSHPHQHQTLPPHHPYPHQHQHPAHHPHP-QPHHQQNHPHHHSHSHLHAHP 317 >gi|59938772 cAMP responsive element binding protein 5 isoform gamma [Homo sapiens] Length = 475 Score = 49.7 bits (117), Expect = 3e-06 Identities = 36/135 (26%), Positives = 53/135 (39%), Gaps = 23/135 (17%) Query: 79 PHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWS 138 PH+ + P H H +PH H HP H P H HPH H H+ H P H P P Sbjct: 245 PHQHQT-LPPH-HPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPL 302 Query: 139 YPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPP 198 + ++ +S + +PP P T G R++V ++ P Sbjct: 303 HTGN-QAQVSPATQQMQPTQTIQPPQP-------TGGRRRRVV-------------DEDP 341 Query: 199 PSYKPLFLDRGYTSA 213 + FL+R +A Sbjct: 342 DERRRKFLERNRAAA 356 Score = 49.7 bits (117), Expect = 3e-06 Identities = 29/81 (35%), Positives = 31/81 (38%), Gaps = 26/81 (32%) Query: 78 PPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPH----AHAHPHP-HHHALPHPP------ 126 PPH H H HP H HP HH PH +H H HP HH PHPP Sbjct: 252 PPHHPY----PHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHTGNQ 307 Query: 127 -----------PTHLSVPPRP 136 PT PP+P Sbjct: 308 AQVSPATQQMQPTQTIQPPQP 328 Score = 47.8 bits (112), Expect = 1e-05 Identities = 24/58 (41%), Positives = 27/58 (46%), Gaps = 4/58 (6%) Query: 82 SRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSY 139 SR + H H H H H H L P P+ H H HP HH PHP P H P S+ Sbjct: 231 SRQDQTPHHHMHSHPHQHQTL--PPHHPYPHQHQHPAHH--PHPQPHHQQNHPHHHSH 284 Score = 32.7 bits (73), Expect = 0.35 Identities = 17/53 (32%), Positives = 22/53 (41%), Gaps = 1/53 (1%) Query: 110 HAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEP 162 H H+HPH H PH P H P +P Q + P + + L A P Sbjct: 240 HMHSHPHQHQTLPPHHPYPHQHQHPAHHPHP-QPHHQQNHPHHHSHSHLHAHP 291 >gi|59938770 cAMP responsive element binding protein 5 isoform alpha [Homo sapiens] Length = 508 Score = 49.7 bits (117), Expect = 3e-06 Identities = 36/135 (26%), Positives = 53/135 (39%), Gaps = 23/135 (17%) Query: 79 PHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWS 138 PH+ + P H H +PH H HP H P H HPH H H+ H P H P P Sbjct: 278 PHQHQT-LPPH-HPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPL 335 Query: 139 YPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPP 198 + ++ +S + +PP P T G R++V ++ P Sbjct: 336 HTGN-QAQVSPATQQMQPTQTIQPPQP-------TGGRRRRVV-------------DEDP 374 Query: 199 PSYKPLFLDRGYTSA 213 + FL+R +A Sbjct: 375 DERRRKFLERNRAAA 389 Score = 49.7 bits (117), Expect = 3e-06 Identities = 29/81 (35%), Positives = 31/81 (38%), Gaps = 26/81 (32%) Query: 78 PPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPH----AHAHPHP-HHHALPHPP------ 126 PPH H H HP H HP HH PH +H H HP HH PHPP Sbjct: 285 PPHHPY----PHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHTGNQ 340 Query: 127 -----------PTHLSVPPRP 136 PT PP+P Sbjct: 341 AQVSPATQQMQPTQTIQPPQP 361 Score = 47.8 bits (112), Expect = 1e-05 Identities = 24/58 (41%), Positives = 27/58 (46%), Gaps = 4/58 (6%) Query: 82 SRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSY 139 SR + H H H H H H L P P+ H H HP HH PHP P H P S+ Sbjct: 264 SRQDQTPHHHMHSHPHQHQTL--PPHHPYPHQHQHPAHH--PHPQPHHQQNHPHHHSH 317 Score = 32.7 bits (73), Expect = 0.35 Identities = 17/53 (32%), Positives = 22/53 (41%), Gaps = 1/53 (1%) Query: 110 HAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEP 162 H H+HPH H PH P H P +P Q + P + + L A P Sbjct: 273 HMHSHPHQHQTLPPHHPYPHQHQHPAHHPHP-QPHHQQNHPHHHSHSHLHAHP 324 >gi|37595553 ring finger protein 111 [Homo sapiens] Length = 986 Score = 48.5 bits (114), Expect = 6e-06 Identities = 53/200 (26%), Positives = 73/200 (36%), Gaps = 35/200 (17%) Query: 64 SLAGSPPGLAPPQP---------PPHRSRLEAPAH--AHSHPHVHVHPLLHHGPAQPHAH 112 S+ P PPQP PP + L P H A + PH H +P P + Sbjct: 624 SMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQASACPHSHGNPPPQTQPPPQVDY 683 Query: 113 AHPHPHH--------HALPHP----PPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMA 160 PHP H HA HP PPTHL+ P P+ PP ++ Sbjct: 684 VIPHPVHAFHSQISSHATSHPVAPPPPTHLASTAAP--IPQHL------PPTHQPISHHI 735 Query: 161 EPPPPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLP--- 217 P ++ L + R V + E+PPP + + G+ +H+P Sbjct: 736 PATAPPAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHRMHPNYGHGHHIHVPQTM 795 Query: 218 -SAPRPAPPCPALCLQADRG 236 S PR AP A L + G Sbjct: 796 SSHPRQAPERSAWELGIEAG 815 Score = 41.2 bits (95), Expect = 0.001 Identities = 30/94 (31%), Positives = 37/94 (39%), Gaps = 9/94 (9%) Query: 58 PLELEGSLAGSPPGLAPP-QPPPHRSRLEAPAHAHSHPH-------VHVHPLLHHGPAQP 109 P L + A P L P QP H AP HPH V ++ H P + Sbjct: 710 PTHLASTAAPIPQHLPPTHQPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQH-PTRA 768 Query: 110 HAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQA 143 H PHPH + H+ VP S+PRQA Sbjct: 769 HERPPPHPHRMHPNYGHGHHIHVPQTMSSHPRQA 802 Score = 33.1 bits (74), Expect = 0.27 Identities = 30/110 (27%), Positives = 42/110 (38%), Gaps = 27/110 (24%) Query: 56 LEPLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQ-PHAHA- 113 ++ +E++ P A +PPPH R+ P + H H H+HV + P Q P A Sbjct: 751 MQRMEVQRRRMMQHPTRAHERPPPHPHRMH-PNYGHGH-HIHVPQTMSSHPRQAPERSAW 808 Query: 114 ------------------HPHPHHHALPHPPPT--HLSVPPRPWSYPRQA 143 HPH H+ H PP HL + P P A Sbjct: 809 ELGIEAGVTAATYTPGALHPHLAHY---HAPPRLHHLQLGALPLMVPDMA 855 Score = 31.6 bits (70), Expect = 0.78 Identities = 20/57 (35%), Positives = 23/57 (40%), Gaps = 4/57 (7%) Query: 89 HAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAES 145 HA HPH HG H H H H H A+P P S P P P Q ++ Sbjct: 495 HALGHPHTSCFQ--QHGHHFQHHHHHHHTPHPAVPVSP--SFSDPACPVERPPQVQA 547 Score = 29.3 bits (64), Expect = 3.9 Identities = 21/64 (32%), Positives = 23/64 (35%), Gaps = 9/64 (14%) Query: 78 PPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHA-----HAHPHPHHHALPHPPPTHLSV 132 PP RL P+ H HH PH H H HHH H P H +V Sbjct: 471 PPAMPRL--PSCCPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHHTP--HPAV 526 Query: 133 PPRP 136 P P Sbjct: 527 PVSP 530 >gi|239751592 PREDICTED: hypothetical protein XP_002347924 [Homo sapiens] Length = 475 Score = 47.8 bits (112), Expect = 1e-05 Identities = 42/171 (24%), Positives = 55/171 (32%), Gaps = 30/171 (17%) Query: 70 PGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLH-------HGPAQPHAHAHPHPHHHAL 122 P + PP + H HS H +HP +H H P H HP H Sbjct: 82 PSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPSIHPF 141 Query: 123 PHP---PPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRK 179 HP PP HL + P P S P + + PP + T R Sbjct: 142 IHPPVHPPIHLHIHP-----PIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRP 196 Query: 180 IVTPFLSRRDSAEKQEQP---PPSYKPLFLDRGYTSALHLPSAPRPAPPCP 227 V P S P PP + P+ ++H + P PP P Sbjct: 197 PVHP------STHPSTHPLIHPPIHPPIH------PSIHPSTHPPTHPPVP 235 Score = 43.5 bits (101), Expect = 2e-04 Identities = 26/69 (37%), Positives = 30/69 (43%), Gaps = 7/69 (10%) Query: 70 PGLAPP-QPPPHRSR---LEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHP 125 P + PP P H S + P H +HP H PL+H P P H HP H HP Sbjct: 176 PSIHPPIHPSTHLSTHPSIRPPVHPSTHPSTH--PLIHP-PIHPPIHPSIHPSTHPPTHP 232 Query: 126 PPTHLSVPP 134 P H S P Sbjct: 233 PVPHPSTHP 241 >gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] Length = 424 Score = 47.8 bits (112), Expect = 1e-05 Identities = 43/144 (29%), Positives = 48/144 (33%), Gaps = 49/144 (34%) Query: 69 PPGLAPPQPPPHRSRLEA--------------PAHAHSHPHVH-----VHP------LLH 103 PPG+ P PPP A P H HSHPH HP L H Sbjct: 254 PPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAH 313 Query: 104 HGPAQPHAHAHPHP------------HHHALPHPPPTHLSVPPR--PWSYPRQAESDM-- 147 HG PH HPH +PHP P + +PPR P+ P M Sbjct: 314 HG---PHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPP 370 Query: 148 ----SKPPCYEEAVLMAEP-PPPY 166 PP P PPPY Sbjct: 371 HGMRGPPPLMPPHGYTGPPRPPPY 394 Score = 34.7 bits (78), Expect = 0.092 Identities = 24/74 (32%), Positives = 27/74 (36%), Gaps = 14/74 (18%) Query: 69 PPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPT 128 PPG+ P PPP P P+ H GP PH P P PP Sbjct: 338 PPGMPHPGPPPMGMPPRGPPFGS--------PMGHPGPMPPHGMRGPPPLM------PPH 383 Query: 129 HLSVPPRPWSYPRQ 142 + PPRP Y Q Sbjct: 384 GYTGPPRPPPYGYQ 397 >gi|239757043 PREDICTED: functional smad suppressing element 18 [Homo sapiens] Length = 996 Score = 47.4 bits (111), Expect = 1e-05 Identities = 29/86 (33%), Positives = 34/86 (39%), Gaps = 24/86 (27%) Query: 80 HRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSY 139 H + AP A +HPH H HP H H HHH P PP L +PP+P Sbjct: 640 HGASAGAPHSAQTHPHHHHHP-------------HHHHHHHHPPQPPSPLLLLPPQP-DE 685 Query: 140 PRQAESDMSKPPCYEEAVLMAEPPPP 165 P + PP PPPP Sbjct: 686 PGSERHHPAPPP----------PPPP 701 Score = 38.5 bits (88), Expect = 0.006 Identities = 29/84 (34%), Positives = 33/84 (39%), Gaps = 24/84 (28%) Query: 60 ELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAH---AHPH 116 +L G+ AG+P Q PH H HPH H H HH P QP + P Sbjct: 638 KLHGASAGAPHSA---QTHPHH---------HHHPHHHHH---HHHPPQPPSPLLLLPPQ 682 Query: 117 P------HHHALPHPPPTHLSVPP 134 P HH P PPP PP Sbjct: 683 PDEPGSERHHPAPPPPPPPPPPPP 706 Score = 28.5 bits (62), Expect = 6.6 Identities = 13/27 (48%), Positives = 15/27 (55%), Gaps = 2/27 (7%) Query: 65 LAGSPPGLAPPQPPPHRSRLEAPAHAH 91 L G+PP PP PPP + L HAH Sbjct: 281 LLGAPP--PPPPPPPPLAELAGAPHAH 305 >gi|239751555 PREDICTED: functional smad suppressing element 18 [Homo sapiens] Length = 1252 Score = 47.4 bits (111), Expect = 1e-05 Identities = 29/86 (33%), Positives = 34/86 (39%), Gaps = 24/86 (27%) Query: 80 HRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSY 139 H + AP A +HPH H HP H H HHH P PP L +PP+P Sbjct: 640 HGASAGAPHSAQTHPHHHHHP-------------HHHHHHHHPPQPPSPLLLLPPQP-DE 685 Query: 140 PRQAESDMSKPPCYEEAVLMAEPPPP 165 P + PP PPPP Sbjct: 686 PGSERHHPAPPP----------PPPP 701 Score = 38.5 bits (88), Expect = 0.006 Identities = 29/84 (34%), Positives = 33/84 (39%), Gaps = 24/84 (28%) Query: 60 ELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAH---AHPH 116 +L G+ AG+P Q PH H HPH H H HH P QP + P Sbjct: 638 KLHGASAGAPHSA---QTHPHH---------HHHPHHHHH---HHHPPQPPSPLLLLPPQ 682 Query: 117 P------HHHALPHPPPTHLSVPP 134 P HH P PPP PP Sbjct: 683 PDEPGSERHHPAPPPPPPPPPPPP 706 Score = 28.5 bits (62), Expect = 6.6 Identities = 13/27 (48%), Positives = 15/27 (55%), Gaps = 2/27 (7%) Query: 65 LAGSPPGLAPPQPPPHRSRLEAPAHAH 91 L G+PP PP PPP + L HAH Sbjct: 281 LLGAPP--PPPPPPPPLAELAGAPHAH 305 >gi|239746067 PREDICTED: functional smad suppressing element 18 [Homo sapiens] Length = 1252 Score = 47.4 bits (111), Expect = 1e-05 Identities = 29/86 (33%), Positives = 34/86 (39%), Gaps = 24/86 (27%) Query: 80 HRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSY 139 H + AP A +HPH H HP H H HHH P PP L +PP+P Sbjct: 640 HGASAGAPHSAQTHPHHHHHP-------------HHHHHHHHPPQPPSPLLLLPPQP-DE 685 Query: 140 PRQAESDMSKPPCYEEAVLMAEPPPP 165 P + PP PPPP Sbjct: 686 PGSERHHPAPPP----------PPPP 701 Score = 38.5 bits (88), Expect = 0.006 Identities = 29/84 (34%), Positives = 33/84 (39%), Gaps = 24/84 (28%) Query: 60 ELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAH---AHPH 116 +L G+ AG+P Q PH H HPH H H HH P QP + P Sbjct: 638 KLHGASAGAPHSA---QTHPHH---------HHHPHHHHH---HHHPPQPPSPLLLLPPQ 682 Query: 117 P------HHHALPHPPPTHLSVPP 134 P HH P PPP PP Sbjct: 683 PDEPGSERHHPAPPPPPPPPPPPP 706 Score = 28.5 bits (62), Expect = 6.6 Identities = 13/27 (48%), Positives = 15/27 (55%), Gaps = 2/27 (7%) Query: 65 LAGSPPGLAPPQPPPHRSRLEAPAHAH 91 L G+PP PP PPP + L HAH Sbjct: 281 LLGAPP--PPPPPPPPLAELAGAPHAH 305 >gi|239746716 PREDICTED: hypothetical protein XP_002343819 [Homo sapiens] Length = 217 Score = 46.6 bits (109), Expect = 2e-05 Identities = 41/160 (25%), Positives = 60/160 (37%), Gaps = 24/160 (15%) Query: 70 PGLAPPQPPPHRSRLEAPAHAHSHP--HVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPP 127 P + P PP S + P ++ HP H H+HP +H P H H HP H P P Sbjct: 23 PSIHPCIHPPTYSSIHPPTYSSIHPSVHPHIHPSIH-----PSTHPHIHPSIH--PSIPS 75 Query: 128 THLSVPP--RPWSYPR-QAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTPF 184 H S+ P RP +Y + +S P ++ + P + + P Sbjct: 76 IHPSIHPSIRPSTYSSIHPSTHISIHPSIHPSIHLHIHPSTHI------------FIHPS 123 Query: 185 LSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRPAP 224 + A PS PLF+ + H P P+ P Sbjct: 124 IHSSIHASTHPHIHPSIYPLFIHPSIHPSTHPPIHPQIHP 163 Score = 36.6 bits (83), Expect = 0.024 Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 2/49 (4%) Query: 84 LEAPAHAHSHPHV--HVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHL 130 + + HA +HPH+ ++PL H P H HP H HP T+L Sbjct: 124 IHSSIHASTHPHIHPSIYPLFIHPSIHPSTHPPIHPQIHPSIHPLLTNL 172 >gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo sapiens] Length = 1858 Score = 46.2 bits (108), Expect = 3e-05 Identities = 47/169 (27%), Positives = 58/169 (34%), Gaps = 42/169 (24%) Query: 69 PPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPP- 127 PP PP P PH ++ P H HV +H H H+ HH P PPP Sbjct: 1628 PPPPPPPAPGPHL--VQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPG 1685 Query: 128 --THLSVPPRPWSYPRQAESD-----MSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKI 180 H PP P + + ++ S PP PPPP S VL Sbjct: 1686 PAPHHHPPPHPSTGLQGLQAQHQHVVNSAPP--------PPPPPPPSSVLASGH------ 1731 Query: 181 VTPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRP-APPCPA 228 SA+ PP PLF PS+ P PP P+ Sbjct: 1732 ------HTTSAQALHHPPHQGPPLF-----------PSSAHPTVPPYPS 1763 >gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo sapiens] Length = 1858 Score = 46.2 bits (108), Expect = 3e-05 Identities = 47/169 (27%), Positives = 58/169 (34%), Gaps = 42/169 (24%) Query: 69 PPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPP- 127 PP PP P PH ++ P H HV +H H H+ HH P PPP Sbjct: 1628 PPPPPPPAPGPHL--VQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPG 1685 Query: 128 --THLSVPPRPWSYPRQAESD-----MSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKI 180 H PP P + + ++ S PP PPPP S VL Sbjct: 1686 PAPHHHPPPHPSTGLQGLQAQHQHVVNSAPP--------PPPPPPPSSVLASGH------ 1731 Query: 181 VTPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRP-APPCPA 228 SA+ PP PLF PS+ P PP P+ Sbjct: 1732 ------HTTSAQALHHPPHQGPPLF-----------PSSAHPTVPPYPS 1763 >gi|157277988 phosphodiesterase 4D isoform 1 [Homo sapiens] Length = 809 Score = 45.4 bits (106), Expect = 5e-05 Identities = 35/107 (32%), Positives = 44/107 (41%), Gaps = 19/107 (17%) Query: 59 LELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPH 118 +E EGS A + G + L+AP H H H +PL QP HPH Sbjct: 1 MEAEGSSAPARAGSGEGSDSAGGATLKAPKHLWRHEQHHQYPL-----RQPQFRLL-HPH 54 Query: 119 HHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPP 165 HH P PPP+ P+P Q + + PP L PPPP Sbjct: 55 HHLPPPPPPS-----PQP-----QPQCPLQPPP---PPPLPPPPPPP 88 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 45.1 bits (105), Expect = 7e-05 Identities = 50/207 (24%), Positives = 66/207 (31%), Gaps = 53/207 (25%) Query: 74 PPQPPPHRSRLEAPAHAHSHPHV----------------------HVHPLLH-------- 103 PP PPP + APA S P P+LH Sbjct: 778 PPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPP 837 Query: 104 HGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKP-------PCYEEA 156 H P P PH + HA+ PP H ++P +P +A + KP P + Sbjct: 838 HLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQT 897 Query: 157 VLMAEPP-------------PPYSEVLTDTRGLY---RKIVTPFLSRRDSAEKQEQPPPS 200 L+ +PP PP + + LY + V P S + Q QPPP Sbjct: 898 PLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPP 957 Query: 201 YKPLFLDRGYTSALHLPSAPRPAPPCP 227 P P P P P P Sbjct: 958 LPPPPHPSVQQQLQQQPPPPPPPQPQP 984 Score = 44.3 bits (103), Expect = 1e-04 Identities = 54/187 (28%), Positives = 72/187 (38%), Gaps = 15/187 (8%) Query: 79 PHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLS---VPPR 135 P + P H H H + PA P P P P PPP PP Sbjct: 723 PKSKKKGHPGREQKKHHHHHHQQMQQAPA-PVPQQPPPPPQQPPPPPPPQQQQQPPPPPP 781 Query: 136 PWSYPRQAESDM--SKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTPFLSRRDSAEK 193 P S P+QA M S PP V + EP P S + D G + + + L + + Sbjct: 782 PPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGS--VFDPIGHFTQPIL-HLPQPELPPH 838 Query: 194 QEQPPPSYKPLFLDRGYT---SALH--LPSAP-RPAPPCPALCLQADRGRRVFPSWTDSE 247 QPP P L++ ALH LP P RP+ AL + R V P+ T + Sbjct: 839 LPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTP 898 Query: 248 LSSREPL 254 L + P+ Sbjct: 899 LLPQPPM 905 Score = 40.4 bits (93), Expect = 0.002 Identities = 38/145 (26%), Positives = 52/145 (35%), Gaps = 21/145 (14%) Query: 61 LEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHP--HVHVHPLLHHGPAQPHAHAHPHPH 118 ++ L PP PPQP P P H P VH+ P+ H P P Sbjct: 966 VQQQLQQQPPPPPPPQPQP------PPQQQHQPPPRPVHLQPM----QFSTHIQQPPPPQ 1015 Query: 119 HHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYR 178 PHPPP PP+P + P+Q P ++ PYS Sbjct: 1016 GQQPPHPPPGQQPPPPQP-AKPQQVIQHHHSPRHHKS--------DPYSTGHLREAPSPL 1066 Query: 179 KIVTPFLSRRDSAEKQEQPPPSYKP 203 I +P +S+ S Q P + +P Sbjct: 1067 MIHSPQMSQFQSLTHQSPPQQNVQP 1091 Score = 30.4 bits (67), Expect = 1.7 Identities = 25/102 (24%), Positives = 34/102 (33%), Gaps = 5/102 (4%) Query: 106 PAQPHAHAHPHPHHHALPH---PPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEP 162 P P A PHP P P VPP+P P PP + + P Sbjct: 213 PNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHP 272 Query: 163 P--PPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPPPSYK 202 P + + +G+ RK T + D + PP K Sbjct: 273 PIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPK 314 >gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens] Length = 2161 Score = 45.1 bits (105), Expect = 7e-05 Identities = 27/81 (33%), Positives = 31/81 (38%), Gaps = 7/81 (8%) Query: 63 GSLAGSP------PGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPH 116 G L SP PG P P + + P+ + L H GP P H PH Sbjct: 943 GRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPH 1002 Query: 117 PHHHALPHPPPTHLSV-PPRP 136 HHH P P P H PP P Sbjct: 1003 HHHHHAPPPQPHHHHAHPPHP 1023 Score = 45.1 bits (105), Expect = 7e-05 Identities = 50/157 (31%), Positives = 61/157 (38%), Gaps = 14/157 (8%) Query: 71 GLAPPQPPPHRS---RLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPP 127 G PP P P S R AP P +HV L + P P P PPP Sbjct: 1463 GTEPPAPHPGVSKPWRSAAPEEPERLP-LHVRFLENCQPRAPVTSGRGPPSEDGPGVPPP 1521 Query: 128 T-HLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTPFLS 186 + SVPP P S PR +E + L+ PPP S + D L+ + + P L Sbjct: 1522 SPRRSVPPSPTS-PRASEEN--------GLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLE 1572 Query: 187 RRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSAPRPA 223 +S EK E P P L A LP P PA Sbjct: 1573 FSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPA 1609 Score = 44.3 bits (103), Expect = 1e-04 Identities = 31/87 (35%), Positives = 37/87 (42%), Gaps = 21/87 (24%) Query: 66 AGSPPGLAPPQPPPHR--SRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHA---HPHPHHH 120 A SP P PP R SR ++ H+ P H HP HH H HA PH HH Sbjct: 964 ASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHH-----HHHAPPPQPHHHHA 1018 Query: 121 ALPHP-----------PPTHLSVPPRP 136 PHP PP L++ P+P Sbjct: 1019 HPPHPPEMETGGSPDDPPPRLALGPQP 1045 Score = 36.2 bits (82), Expect = 0.032 Identities = 34/123 (27%), Positives = 41/123 (33%), Gaps = 11/123 (8%) Query: 53 ALELEPLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAH 112 AL L+ S G PP+PP R P H PH H P+L A P Sbjct: 1356 ALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASP--- 1412 Query: 113 AHPHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAV------LMAEPPPPY 166 P P L + P S P S + + P V L EPP P+ Sbjct: 1413 --PDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPH 1470 Query: 167 SEV 169 V Sbjct: 1471 PGV 1473 >gi|18959210 WIRE protein [Homo sapiens] Length = 440 Score = 45.1 bits (105), Expect = 7e-05 Identities = 43/168 (25%), Positives = 56/168 (33%), Gaps = 27/168 (16%) Query: 69 PPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPH-PHHHALPH--- 124 PP PP P R+ + A P P + +GP+ P + P P H H Sbjct: 228 PPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKT 287 Query: 125 PPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLTDTRGLYRKIVTPF 184 P P PP P S S+ PP + A PPPP + Sbjct: 288 PGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVI--------------- 332 Query: 185 LSRRDSAEKQEQPPPSYK-----PLFLDRGYTSALHLPSAPRPAPPCP 227 R+ A PPP Y+ P + P+ P P PP P Sbjct: 333 ---RNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPP 377 Score = 35.4 bits (80), Expect = 0.054 Identities = 30/100 (30%), Positives = 36/100 (36%), Gaps = 22/100 (22%) Query: 73 APPQPPPHRSR----LEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPT 128 APP PPP R P H+ P + P P HP P PPP Sbjct: 176 APPPPPPGRRANAPPTPLPMHSSKAPAYN-----REKPLPPTPGQRLHPGREGPPAPPP- 229 Query: 129 HLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSE 168 + PP P + R S S +A PPPPY + Sbjct: 230 -VKPPPSPVNI-RTGPSGQS----------LAPPPPPYRQ 257 >gi|12751477 forkhead box L2 [Homo sapiens] Length = 376 Score = 43.9 bits (102), Expect = 2e-04 Identities = 32/84 (38%), Positives = 34/84 (40%), Gaps = 20/84 (23%) Query: 67 GSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPP 126 G PP APP PP H HPH H H L H A P P P HH PP Sbjct: 278 GGPPA-APPPPP------------HPHPHPHAHHL--HAAAAPP----PAPPHHGAAAPP 318 Query: 127 PTHLSVPPRPWSYPRQAESDMSKP 150 P LS P P + A + S P Sbjct: 319 PGQLS-PASPATAAPPAPAPTSAP 341 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 43.9 bits (102), Expect = 2e-04 Identities = 54/188 (28%), Positives = 65/188 (34%), Gaps = 31/188 (16%) Query: 51 LRALELEPLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPH 110 L +L + PLE + SLA PP L P PA + P ++ P L P Q Sbjct: 504 LSSLIMPPLETQSSLA--PPSLQTP-----------PASLTTPPLENL-PSLAPPPLQTA 549 Query: 111 AHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQ------AESDMSKPPCYEEAVLMAEPPP 164 + PH P P P L PP P + P A PP L P P Sbjct: 550 SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP 609 Query: 165 PYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPP--PSYKPLFLDRGYTS---ALHLPSA 219 P S + T + P L S PP P PL A+HL A Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPS------PPASPPLSPLATPSPQAPNALAVHLLQA 663 Query: 220 PRPAPPCP 227 P PP P Sbjct: 664 PFSPPPSP 671 Score = 36.2 bits (82), Expect = 0.032 Identities = 35/117 (29%), Positives = 41/117 (35%), Gaps = 17/117 (14%) Query: 56 LEPLELEGSLAGSPPGL-APPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAH 114 L PL SP G A P PPP + PA P PL A Sbjct: 296 LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSP-----PL-----------AT 339 Query: 115 PHPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEEAVLMAEPPPPYSEVLT 171 P P P PP+ ++P P + P QA M+ PP L PP LT Sbjct: 340 PLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLT 396 Score = 36.2 bits (82), Expect = 0.032 Identities = 61/228 (26%), Positives = 73/228 (32%), Gaps = 36/228 (15%) Query: 69 PPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQ----PHAHAHPHPHHHALPH 124 PP APP P P + P V PLL P Q P A P P Sbjct: 728 PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQ 787 Query: 125 PPPTHLSVPP------RPWSYPRQAESDMS--------------KPPCYEEAVLMAEPPP 164 PP L+ PP P S+P QA S PP +L P P Sbjct: 788 APPA-LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 846 Query: 165 PYSEVL-----TDTRGLYRKIVTPFLSRRDSAEKQEQPPPSYKPLFLDRGYTSALHLPSA 219 P S L T G + P L+ + PPPS P G A H SA Sbjct: 847 PASPTLQAPRRPPTPGPDTSVSGPRLTL--ALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 904 Query: 220 PRPAPPCPALCLQADRGRRVFPSWTDSELSSREPLEHGAWRLPVSIPL 267 + G P D+EL++ P AW + PL Sbjct: 905 TSTPEELRGYDSGPEGGAAASPP-PDAELAACHP---AAWSRGPAPPL 948 Score = 33.5 bits (75), Expect = 0.21 Identities = 48/185 (25%), Positives = 58/185 (31%), Gaps = 37/185 (20%) Query: 54 LELEPLELEGSLAGSPP--GLAPPQPPPHRSR----LEAPAHAHSHPHVHVHPLLHHGPA 107 L L PL+ S SPP LA P P + L+AP P V PA Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP---FSPPA 681 Query: 108 QPHAHAHPHPHHHALPHPPPTHLSVPPRPWSYPRQAES---DMSKPPCYEEAVLMAEPPP 164 P P A P L VPP P + P + S PP L P P Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741 Query: 165 PYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPPPSYKPLF----LDRGYTSALHLPSAP 220 P S ++ + PPP PL L + LP +P Sbjct: 742 PASPPMSPS---------------------ATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780 Query: 221 RPAPP 225 PP Sbjct: 781 LAKPP 785 Score = 33.1 bits (74), Expect = 0.27 Identities = 40/120 (33%), Positives = 47/120 (39%), Gaps = 16/120 (13%) Query: 53 ALELEPLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQP--H 110 +L PL++ S SPP PPP +AP + P + V P PA P Sbjct: 698 SLAAPPLQVPPSPPASPPMSPSATPPP-----QAPPPL-AAPPLQVPP---SPPASPPMS 748 Query: 111 AHAHPHPHHHALPHPPPTHLSVPPR-PWSYPRQ--AESDMSKPPCYEEAVLMAEPPPPYS 167 A P P L PP L VPP P S P A+ PP L A P PP S Sbjct: 749 PSATPPPRVPPLLAAPP--LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPAS 806 Score = 29.6 bits (65), Expect = 3.0 Identities = 52/196 (26%), Positives = 69/196 (35%), Gaps = 28/196 (14%) Query: 56 LEPLELEGSLAGSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAH-AH 114 + P+++ SL P L P P S L+A S H L P Q A Sbjct: 386 IPPIQVPHSLTS--PSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTS 443 Query: 115 PHPHHHALPHPPPTH--LSVPPRPWSYPRQ-----AESDMSKPPCYEEAVLMAE-----P 162 P P PP LS+P P P Q A S +S P ++ P Sbjct: 444 PSRPASTPPDSPPLQAPLSLPASP---PLQTSLSPAVSPLSSPLTIHPLQALSSLASHSP 500 Query: 163 PPPYSEVLTDTRGLYRKIVTPFLSRRDSAEKQEQPP----PSYKPLFLDRGYTSALHLPS 218 P S ++ + P L ++ PP PS P L T++ L + Sbjct: 501 QAPLSSLIMPPLETQSSLAPPSLQTPPAS--LTTPPLENLPSLAPPPLQ---TASAPLTT 555 Query: 219 APRPAPPCPALC-LQA 233 PPCPA C LQA Sbjct: 556 PHLETPPCPAPCPLQA 571 Score = 28.9 bits (63), Expect = 5.1 Identities = 45/185 (24%), Positives = 60/185 (32%), Gaps = 19/185 (10%) Query: 58 PLELEGSLAGSPPGLAPPQPPPHRSR--LEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHP 115 P SL SP PPQ PP + L+ P + P + P P + + P Sbjct: 812 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA-PRRPPTPGPDTSVSGP 870 Query: 116 HPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPPCYEE--------AVLMAEPPPPYS 167 P PPP P S P A S EE A PPP + Sbjct: 871 RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA 930 Query: 168 EVLTDTRGLYRKIVTPFLSRRDSAEKQEQPPPSYKP--------LFLDRGYTSALHLPSA 219 E+ + + P L+ R + PP+ P ++ G SA P A Sbjct: 931 ELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA 990 Query: 220 PRPAP 224 P P Sbjct: 991 LDPGP 995 >gi|148762982 hypothetical protein LOC387640 [Homo sapiens] Length = 908 Score = 43.9 bits (102), Expect = 2e-04 Identities = 27/70 (38%), Positives = 29/70 (41%), Gaps = 21/70 (30%) Query: 77 PPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSVPPRP 136 PPPH H H H H H H HH AQP +H PHHH P HL Sbjct: 334 PPPH--------HHHHHHHHHHH---HHHRAQPPQQSHHPPHHHR----PQPHLG----- 373 Query: 137 WSYPRQAESD 146 S+P SD Sbjct: 374 -SFPESCSSD 382 >gi|50345831 forkhead box J3 [Homo sapiens] Length = 622 Score = 43.9 bits (102), Expect = 2e-04 Identities = 25/67 (37%), Positives = 27/67 (40%), Gaps = 6/67 (8%) Query: 74 PPQPPPHRSRLEAPAHAHSHPHVHVHPLLHHGPAQPHAHAHPHPHHHALPHPPPTHLSV- 132 P PPHR P H PH HP H PH HP PH H HP H ++ Sbjct: 379 PSPHPPHRPH-GLPQHPQRSPHPAPHPQQHSQLQSPHPQ-HPSPHQHIQHHPNHQHQTLT 436 Query: 133 ---PPRP 136 PP P Sbjct: 437 HQAPPPP 443 Score = 37.7 bits (86), Expect = 0.011 Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 20/87 (22%) Query: 92 SHPHVHVHPLLH-----HG-PAQPHAHAHPHPH---HHALPHPPPTHLSVPPRPWSYPRQ 142 SHP +H P H HG P P HP PH H L P P H P P + Sbjct: 371 SHPQMHTQPSPHPPHRPHGLPQHPQRSPHPAPHPQQHSQLQSPHPQH----PSPHQH--- 423 Query: 143 AESDMSKPPCYEEAVLMAEPPPPYSEV 169 + P ++ L + PPP +V Sbjct: 424 ----IQHHPNHQHQTLTHQAPPPPQQV 446 >gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] Length = 638 Score = 43.5 bits (101), Expect = 2e-04 Identities = 49/180 (27%), Positives = 64/180 (35%), Gaps = 28/180 (15%) Query: 67 GSPPGLAPPQPPPHRSRLEAPAHAHSHPHVHVH----PL------LHHGPAQPHAHAHPH 116 G PP P PPP P H H P + + P+ LH G P Sbjct: 419 GPPPPWMQPPPPPMNQGPHPPGH-HGPPPMDQYLGSTPVGSGVYRLHQGKGMM-----PP 472 Query: 117 PHHHALPHPPPTHLSVPPRPWSYP----RQAESDMSKPPCYEEAVLMAEPPPPYSEVLTD 172 P +P PPP PP P S P +Q + PP ++ + P P T Sbjct: 473 PPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTT 532 Query: 173 TRGLYRKIVTPFLSRRDSA-----EKQEQPPPSYKPLFLDRGYTSALHLPSAPRPAPPCP 227 T + P+ ++ +A Q Q P+ P L G L P AP P PP P Sbjct: 533 TTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVP--LPPGVQPPLP-PGAPPPPPPPP 589 Score = 32.7 bits (73), Expect = 0.35 Identities = 28/107 (26%), Positives = 36/107 (33%), Gaps = 20/107 (18%) Query: 65 LAGSPPGLAPPQPPPHRSRLEAPAH---------AHSHPHVHVHPLLHHGPAQ-PHAHAH 114 LA +P AP PP S + + S P+ +H GP PH+ H Sbjct: 340 LASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPH 399 Query: 115 P----------HPHHHALPHPPPTHLSVPPRPWSYPRQAESDMSKPP 151 P HP H PPP + PP P + PP Sbjct: 400 PLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPP 446 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.138 0.463 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,361,296 Number of Sequences: 37866 Number of extensions: 1122118 Number of successful extensions: 12256 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 174 Number of HSP's successfully gapped in prelim test: 667 Number of HSP's that attempted gapping in prelim test: 7922 Number of HSP's gapped (non-prelim): 3164 length of query: 274 length of database: 18,247,518 effective HSP length: 101 effective length of query: 173 effective length of database: 14,423,052 effective search space: 2495187996 effective search space used: 2495187996 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.