Search of human proteins with 21314600

Search of human proteins with 21314600

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21314600 carcinoembryonic antigen-related cell adhesion
molecule 8 [Homo sapiens]
         (349 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21314600 carcinoembryonic antigen-related cell adhesion molec...   713   0.0  
gi|40255013 carcinoembryonic antigen-related cell adhesion molec...   548   e-156
gi|68161541 carcinoembryonic antigen-related cell adhesion molec...   529   e-150
gi|19923195 carcinoembryonic antigen-related cell adhesion molec...   529   e-150
gi|98986445 carcinoembryonic antigen-related cell adhesion molec...   494   e-140
gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2 [...   385   e-107
gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo sapi...   382   e-106
gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo sapi...   379   e-105
gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo sapi...   379   e-105
gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1...   377   e-104
gi|5901930 carcinoembryonic antigen-related cell adhesion molecu...   322   4e-88
gi|194328710 pregnancy specific beta-1-glycoprotein 8 isoform b ...   301   7e-82
gi|51510887 pregnancy specific beta-1-glycoprotein 8 isoform a [...   301   7e-82
gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens]   300   1e-81
gi|157805480 pregnancy specific beta-1-glycoprotein 7 precursor ...   300   1e-81
gi|42560235 pregnancy specific beta-1-glycoprotein 4 isoform 1 [...   296   1e-80
gi|156616284 pregnancy specific beta-1-glycoprotein 9 [Homo sapi...   294   7e-80
gi|109240546 pregnancy specific beta-1-glycoprotein 3 [Homo sapi...   293   2e-79
gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [H...   283   2e-76
gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b [...   283   2e-76
gi|194328712 pregnancy specific beta-1-glycoprotein 8 isoform c ...   244   8e-65
gi|164663826 pregnancy specific beta-1-glycoprotein 11 isoform 2...   220   2e-57
gi|164663824 pregnancy specific beta-1-glycoprotein 11 isoform 2...   220   2e-57
gi|52317156 carcinoembryonic antigen-related cell adhesion molec...   206   2e-53
gi|148612793 carcinoembryonic antigen-related cell adhesion mole...   204   7e-53
gi|121114300 carcinoembryonic antigen-related cell adhesion mole...   202   4e-52
gi|85861202 carcinoembryonic antigen-related cell adhesion molec...   164   8e-41
gi|71143132 carcinoembryonic antigen-related cell adhesion molec...   159   4e-39
gi|156564378 carcinoembryonic antigen-related cell adhesion mole...   117   2e-26
gi|156564393 carcinoembryonic antigen-related cell adhesion mole...   117   2e-26

>gi|21314600 carcinoembryonic antigen-related cell adhesion molecule
           8 [Homo sapiens]
          Length = 349

 Score =  713 bits (1841), Expect = 0.0
 Identities = 349/349 (100%), Positives = 349/349 (100%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ
Sbjct: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
           DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY
Sbjct: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120

Query: 121 TLQVIKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWV 180
           TLQVIKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWV
Sbjct: 121 TLQVIKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWV 180

Query: 181 NGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAP 240
           NGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAP
Sbjct: 181 NGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAP 240

Query: 241 TISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYACH 300
           TISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYACH
Sbjct: 241 TISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYACH 300

Query: 301 TTNSATGRNRTTVRMITVSDALVQGSSPGLSARATVSIMIGVLARVALI 349
           TTNSATGRNRTTVRMITVSDALVQGSSPGLSARATVSIMIGVLARVALI
Sbjct: 301 TTNSATGRNRTTVRMITVSDALVQGSSPGLSARATVSIMIGVLARVALI 349


>gi|40255013 carcinoembryonic antigen-related cell adhesion molecule
           6 (non-specific cross reacting antigen) [Homo sapiens]
          Length = 344

 Score =  548 bits (1413), Expect = e-156
 Identities = 273/349 (78%), Positives = 292/349 (83%), Gaps = 5/349 (1%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MGP SAP CR  +PW+ +LLTASL TFWNPPTTA+LTIE+ P N AEGKEVLLL HNLPQ
Sbjct: 1   MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
           +  GY+WYKGE VD N  I+GYVI  QQ TPGPAYS RETIYPNASLL++NVT+NDTG Y
Sbjct: 61  NRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFY 120

Query: 121 TLQVIKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWV 180
           TLQVIK +L++EE TGQF V+PE PKPSISSNNSNPVEDKDAVAFTCEPE QNTTYLWWV
Sbjct: 121 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWV 180

Query: 181 NGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAP 240
           NGQSLPVSPRLQLSNGN TLTLLSV RND G YECEIQNPASAN SDPVTLNVLYGPD P
Sbjct: 181 NGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDGP 240

Query: 241 TISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYACH 300
           TISPS   Y  G NLNLSCHAASNPP+QYSW +NGTFQQ TQ+LFIPNIT  NSGSY C 
Sbjct: 241 TISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQ 300

Query: 301 TTNSATGRNRTTVRMITVSDALVQGSSPGLSARATVSIMIGVLARVALI 349
             NSATG NRTTV MITVS     GS+P LSA ATV I IGVLARVALI
Sbjct: 301 AHNSATGLNRTTVTMITVS-----GSAPVLSAVATVGITIGVLARVALI 344


>gi|68161541 carcinoembryonic antigen-related cell adhesion molecule
           1 isoform 2 precursor [Homo sapiens]
          Length = 464

 Score =  529 bits (1363), Expect = e-150
 Identities = 255/335 (76%), Positives = 281/335 (83%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MG +SAP  R R+PWQGLLLTASL TFWNPPTTAQLT E++P N AEGKEVLLLVHNLPQ
Sbjct: 1   MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
              GY+WYKGE VD NR+I+GY I  QQ TPGPA S RETIYPNASLL++NVT+NDTG Y
Sbjct: 61  QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120

Query: 121 TLQVIKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWV 180
           TLQVIK +L++EE TGQF V+PE PKPSISSNNSNPVEDKDAVAFTCEPETQ+TTYLWW+
Sbjct: 121 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI 180

Query: 181 NGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAP 240
           N QSLPVSPRLQLSNGNRTLTLLSVTRND GPYECEIQNP SAN SDPVTLNV YGPD P
Sbjct: 181 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP 240

Query: 241 TISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYACH 300
           TISPSDTYY  G NL+LSC+AASNPP+QYSW +NGTFQQ TQ+LFIPNIT  NSGSY CH
Sbjct: 241 TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH 300

Query: 301 TTNSATGRNRTTVRMITVSDALVQGSSPGLSARAT 335
             NS TG NRTTV+ I V++     + P + A  T
Sbjct: 301 ANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKT 335



 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 54/144 (37%), Positives = 74/144 (51%), Gaps = 6/144 (4%)

Query: 107 LLMRNVTRNDTGSYTLQ----VIKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDA 162
           L + N+T N++GSYT      V   N  + +      + P   KP I ++ +    DKD+
Sbjct: 284 LFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDS 343

Query: 163 VAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPAS 222
           V  TC       +  W+   QSLP S R++LS GN TL++  V R D G Y CE+ NP S
Sbjct: 344 VNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPIS 403

Query: 223 ANFSDPVTLNVLYG--PDAPTISP 244
            N SDP+ LNV Y   P    +SP
Sbjct: 404 KNQSDPIMLNVNYNALPQENGLSP 427


>gi|19923195 carcinoembryonic antigen-related cell adhesion molecule
           1 isoform 1 precursor [Homo sapiens]
          Length = 526

 Score =  529 bits (1363), Expect = e-150
 Identities = 255/335 (76%), Positives = 281/335 (83%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MG +SAP  R R+PWQGLLLTASL TFWNPPTTAQLT E++P N AEGKEVLLLVHNLPQ
Sbjct: 1   MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
              GY+WYKGE VD NR+I+GY I  QQ TPGPA S RETIYPNASLL++NVT+NDTG Y
Sbjct: 61  QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY 120

Query: 121 TLQVIKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWV 180
           TLQVIK +L++EE TGQF V+PE PKPSISSNNSNPVEDKDAVAFTCEPETQ+TTYLWW+
Sbjct: 121 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI 180

Query: 181 NGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAP 240
           N QSLPVSPRLQLSNGNRTLTLLSVTRND GPYECEIQNP SAN SDPVTLNV YGPD P
Sbjct: 181 NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP 240

Query: 241 TISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYACH 300
           TISPSDTYY  G NL+LSC+AASNPP+QYSW +NGTFQQ TQ+LFIPNIT  NSGSY CH
Sbjct: 241 TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH 300

Query: 301 TTNSATGRNRTTVRMITVSDALVQGSSPGLSARAT 335
             NS TG NRTTV+ I V++     + P + A  T
Sbjct: 301 ANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKT 335



 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 54/144 (37%), Positives = 74/144 (51%), Gaps = 6/144 (4%)

Query: 107 LLMRNVTRNDTGSYTLQ----VIKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDA 162
           L + N+T N++GSYT      V   N  + +      + P   KP I ++ +    DKD+
Sbjct: 284 LFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDS 343

Query: 163 VAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPAS 222
           V  TC       +  W+   QSLP S R++LS GN TL++  V R D G Y CE+ NP S
Sbjct: 344 VNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPIS 403

Query: 223 ANFSDPVTLNVLYG--PDAPTISP 244
            N SDP+ LNV Y   P    +SP
Sbjct: 404 KNQSDPIMLNVNYNALPQENGLSP 427


>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
           5 preproprotein [Homo sapiens]
          Length = 702

 Score =  494 bits (1272), Expect = e-140
 Identities = 241/314 (76%), Positives = 260/314 (82%)

Query: 5   SAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQDPRG 64
           SAP  RW IPWQ LLLTASL TFWNPPTTA+LTIE+ P N AEGKEVLLLVHNLPQ   G
Sbjct: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64

Query: 65  YNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSYTLQV 124
           Y+WYKGE VD NR+IIGYVI  QQ TPGPAYS RE IYPNASLL++N+ +NDTG YTL V
Sbjct: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124

Query: 125 IKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQS 184
           IK +L++EE TGQF V+PE PKPSISSNNS PVEDKDAVAFTCEPETQ+ TYLWWVN QS
Sbjct: 125 IKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQS 184

Query: 185 LPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTISP 244
           LPVSPRLQLSNGNRTLTL +VTRND   Y+CE QNP SA  SD V LNVLYGPDAPTISP
Sbjct: 185 LPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISP 244

Query: 245 SDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYACHTTNS 304
            +T Y +G NLNLSCHAASNPP+QYSW VNGTFQQ TQ+LFIPNIT  NSGSY C   NS
Sbjct: 245 LNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQAHNS 304

Query: 305 ATGRNRTTVRMITV 318
            TG NRTTV  ITV
Sbjct: 305 DTGLNRTTVTTITV 318



 Score =  307 bits (787), Expect = 8e-84
 Identities = 160/244 (65%), Positives = 179/244 (73%), Gaps = 4/244 (1%)

Query: 107 LLMRNVTRNDTGSYTLQVIK-LNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDAVAF 165
           L + N+T  ++G YT Q     +  S       +V  E PKPSISSNNS PVEDKDAVAF
Sbjct: 462 LFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAF 521

Query: 166 TCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANF 225
           TCEPE QNTTYLWWVNGQSLPVSPRLQLSNGNRTLTL +VTRND   Y C IQN  SAN 
Sbjct: 522 TCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANR 581

Query: 226 SDPVTLNVLYGPDAPTISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQKLF 285
           SDPVTL+VLYGPD P ISP D+ Y +G NLNLSCH+ASNP  QYSW +NG  QQ+TQ LF
Sbjct: 582 SDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLF 641

Query: 286 IPNITTKNSGSYACHTTNSATGRNRTTVRMITVSDALVQGSSPGLSARATVSIMIGVLAR 345
           I  IT  N+G+YAC  +N ATGRN + V+ ITVS     G+SPGLSA ATV IMIGVL  
Sbjct: 642 IAKITPNNNGTYACFVSNLATGRNNSIVKSITVS---ASGTSPGLSAGATVGIMIGVLVG 698

Query: 346 VALI 349
           VALI
Sbjct: 699 VALI 702



 Score =  302 bits (773), Expect = 3e-82
 Identities = 161/291 (55%), Positives = 190/291 (65%), Gaps = 28/291 (9%)

Query: 37  TIEAVPSNAAEGKEVLLLVHNLPQDPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYS 96
           TI  + ++   G+ + L  H     P  Y+W+   T              QQ T      
Sbjct: 241 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTF-------------QQSTQ----- 282

Query: 97  NRETIYPNASLLMRNVTRNDTGSYTLQVIKLNL-MSEEVTGQFSVHPETPKPSISSNNSN 155
                     L + N+T N++GSYT Q    +  ++       +V+ E PKP I+SNNSN
Sbjct: 283 ---------ELFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSN 333

Query: 156 PVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYEC 215
           PVED+DAVA TCEPE QNTTYLWWVN QSLPVSPRLQLSN NRTLTLLSVTRNDVGPYEC
Sbjct: 334 PVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYEC 393

Query: 216 EIQNPASANFSDPVTLNVLYGPDAPTISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNG 275
            IQN  S + SDPV LNVLYGPD PTISPS TYY  GVNL+LSCHAASNPP+QYSW ++G
Sbjct: 394 GIQNKLSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDG 453

Query: 276 TFQQYTQKLFIPNITTKNSGSYACHTTNSATGRNRTTVRMITVSDALVQGS 326
             QQ+TQ+LFI NIT KNSG Y C   NSA+G +RTTV+ ITVS  L + S
Sbjct: 454 NIQQHTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPS 504



 Score = 35.0 bits (79), Expect = 0.100
 Identities = 38/148 (25%), Positives = 62/148 (41%), Gaps = 16/148 (10%)

Query: 104 NASLLMRNVTRNDTGSYTLQV---IKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDK 160
           N +L + NVTRND  +Y   +   +  N  S+ VT      P+T  P IS  +S+ +   
Sbjct: 553 NRTLTLFNVTRNDARAYVCGIQNSVSAN-RSDPVTLDVLYGPDT--PIISPPDSSYLSGA 609

Query: 161 DAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNP 220
           +           +  Y W +NG  +P           + L +  +T N+ G Y C + N 
Sbjct: 610 NLNLSCHSASNPSPQYSWRING--IP-------QQHTQVLFIAKITPNNNGTYACFVSNL 660

Query: 221 ASA-NFSDPVTLNVLYGPDAPTISPSDT 247
           A+  N S   ++ V     +P +S   T
Sbjct: 661 ATGRNNSIVKSITVSASGTSPGLSAGAT 688


>gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2
           [Homo sapiens]
          Length = 326

 Score =  385 bits (988), Expect = e-107
 Identities = 192/322 (59%), Positives = 232/322 (72%), Gaps = 2/322 (0%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MGP+SAP C  RI W+G+LLTASL  FWNPPTTAQ+TIEA P   +EGK+VLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTQRITWKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
           +  GY WYKG+       I  YV+  Q+I  GPAYS RE +Y NASLL++NVT+ D GSY
Sbjct: 61  NLAGYIWYKGQMTYLYHYITSYVVDGQRIIYGPAYSGRERVYSNASLLIQNVTQEDAGSY 120

Query: 121 TLQVIKLNLMSEEVTGQFS--VHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLW 178
           TL +IK    +  VTG F+  +H ETPKPSISS+N NP E  +AV  TC+P T   +Y W
Sbjct: 121 TLHIIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAMEAVILTCDPATPAASYQW 180

Query: 179 WVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPD 238
           W+NGQSLP++ RLQLS  NRTL +  VT+   GPYECEI+NP SA+ SDPVTLN+L+GPD
Sbjct: 181 WMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLHGPD 240

Query: 239 APTISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYA 298
            P+I PS TYY +G NL LSC A SNP +QYSW++NG FQ   QKL IP ITTK+SG YA
Sbjct: 241 LPSIYPSFTYYRSGENLYLSCFAESNPRAQYSWTINGKFQLSGQKLSIPQITTKHSGLYA 300

Query: 299 CHTTNSATGRNRTTVRMITVSD 320
           C   NSATG+  +    + VSD
Sbjct: 301 CSVRNSATGKESSKSITVKVSD 322


>gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo
           sapiens]
          Length = 335

 Score =  382 bits (981), Expect = e-106
 Identities = 195/333 (58%), Positives = 233/333 (69%), Gaps = 2/333 (0%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MGP+SAP C   I W+GLL+TASL  FWN PTTAQ+TIEA P   +EGK+VLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTEHIKWKGLLVTASLLNFWNLPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
           +  GY WYKG+  D    I  YV+  Q I  GPAYS RET Y NASLL++NVTR D GSY
Sbjct: 61  NLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY 120

Query: 121 TLQVIKLNLMSEEVTGQFS--VHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLW 178
           TL +IK    +  VTG F+  ++ ETPKPSISS+N NP E  + V  TC+PET +T+Y W
Sbjct: 121 TLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETVILTCDPETPDTSYQW 180

Query: 179 WVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPD 238
           W+NGQSLP++ R QLS  NRTL L  VT+   GPYECEI+N  SA+ SDPVTLN+L+GPD
Sbjct: 181 WMNGQSLPMTHRFQLSETNRTLFLFGVTKYTAGPYECEIRNSGSASRSDPVTLNLLHGPD 240

Query: 239 APTISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYA 298
            P I PS T Y +G NL LSC A SNPP+QYSW++NG FQQ  Q LFIP ITTK+SG Y 
Sbjct: 241 LPRIHPSYTNYRSGDNLYLSCFANSNPPAQYSWTINGKFQQSGQNLFIPQITTKHSGLYV 300

Query: 299 CHTTNSATGRNRTTVRMITVSDALVQGSSPGLS 331
           C   NSATG   +T   + VS +   G  P L+
Sbjct: 301 CSVRNSATGEESSTSLTVKVSASTRIGLLPLLN 333


>gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo
           sapiens]
          Length = 335

 Score =  379 bits (974), Expect = e-105
 Identities = 187/321 (58%), Positives = 230/321 (71%), Gaps = 2/321 (0%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MGP+SAP C   I W+GLLLTASL  FWN P TAQ+TIEA+P   +EGK+VLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
           +  GY WYKG+ +D    I  YV+  Q    GPAY+ RET+Y NASLL++NVTR D GSY
Sbjct: 61  NLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSY 120

Query: 121 TLQVIKLNLMSEEVTGQFS--VHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLW 178
           TL +IK    +  VTG F+  ++ + PKP I+ NNS P E+KD +AFTCEP+++N TY+W
Sbjct: 121 TLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIW 180

Query: 179 WVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPD 238
           W+NGQSLPVSPR++    NR L L SVTRN+ GPYECEI++      SDPVTLNVLYGPD
Sbjct: 181 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPD 240

Query: 239 APTISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYA 298
            P+I PS TYY +G NL LSC A SNPP++Y W++NG FQQ  QKL IP ITTK+ G Y 
Sbjct: 241 LPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYT 300

Query: 299 CHTTNSATGRNRTTVRMITVS 319
           C   NSATG+  +    + VS
Sbjct: 301 CSVRNSATGKESSKSMTVEVS 321


>gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo
           sapiens]
          Length = 335

 Score =  379 bits (974), Expect = e-105
 Identities = 187/321 (58%), Positives = 230/321 (71%), Gaps = 2/321 (0%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MGP+SAP C   I W+GLLLTASL  FWN P TAQ+TIEA+P   +EGK+VLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
           +  GY WYKG+ +D    I  YV+  Q    GPAY+ RET+Y NASLL++NVTR D GSY
Sbjct: 61  NLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSY 120

Query: 121 TLQVIKLNLMSEEVTGQFS--VHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLW 178
           TL +IK    +  VTG F+  ++ + PKP I+ NNS P E+KD +AFTCEP+++N TY+W
Sbjct: 121 TLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIW 180

Query: 179 WVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPD 238
           W+NGQSLPVSPR++    NR L L SVTRN+ GPYECEI++      SDPVTLNVLYGPD
Sbjct: 181 WLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPD 240

Query: 239 APTISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYA 298
            P+I PS TYY +G NL LSC A SNPP++Y W++NG FQQ  QKL IP ITTK+ G Y 
Sbjct: 241 LPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYT 300

Query: 299 CHTTNSATGRNRTTVRMITVS 319
           C   NSATG+  +    + VS
Sbjct: 301 CSVRNSATGKESSKSMTVEVS 321


>gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1
           [Homo sapiens]
          Length = 335

 Score =  377 bits (967), Expect = e-104
 Identities = 190/320 (59%), Positives = 227/320 (70%), Gaps = 2/320 (0%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MGP+SAP C   I W+GLLLTA L  FWN PTTAQ+ IEA P   +EGK+VLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTEHIKWKGLLLTALLLNFWNLPTTAQVMIEAQPPKVSEGKDVLLLVHNLPQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
           +  GY WYKG+  D    I  YV+  Q I  GPAYS RET+Y NASLL++NVTR D GSY
Sbjct: 61  NLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETVYSNASLLIQNVTREDAGSY 120

Query: 121 TLQVIKLNLMSEEVTGQFS--VHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLW 178
           TL +IK    +  VTG F+  ++ ETPKPSISS+N NP E  + V  TC PET + +YLW
Sbjct: 121 TLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETVILTCNPETPDASYLW 180

Query: 179 WVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPD 238
           W+NGQSLP++ R+QLS  NRTL L  VT+   GPYECEI N  SA+ SDPVTLN+L+GPD
Sbjct: 181 WMNGQSLPMTHRMQLSETNRTLFLFGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPD 240

Query: 239 APTISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYA 298
            P I PS T Y++G NL+LSC A SNPP+QYSW++NG FQ   QKLFIP IT K++G YA
Sbjct: 241 LPRIFPSVTSYYSGENLDLSCFANSNPPAQYSWTINGKFQLSGQKLFIPQITPKHNGLYA 300

Query: 299 CHTTNSATGRNRTTVRMITV 318
           C   NSATG   +T   I V
Sbjct: 301 CSARNSATGEESSTSLTIRV 320


>gi|5901930 carcinoembryonic antigen-related cell adhesion molecule
           7 [Homo sapiens]
          Length = 265

 Score =  322 bits (824), Expect = 4e-88
 Identities = 163/236 (69%), Positives = 183/236 (77%), Gaps = 1/236 (0%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MG  SA   R  IPWQGLLLTASL TFWN P +AQ  I+ VP N AEGKEVLL+VHN  Q
Sbjct: 1   MGSPSACPYRVCIPWQGLLLTASLLTFWNLPNSAQTNIDVVPFNVAEGKEVLLVVHNESQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVIS-NQQITPGPAYSNRETIYPNASLLMRNVTRNDTGS 119
           +  GYNWYKGE V AN RIIGYV + +Q+  PGPA++ RETIYPN +LL++NVT ND G 
Sbjct: 61  NLYGYNWYKGERVHANYRIIGYVKNISQENAPGPAHNGRETIYPNGTLLIQNVTHNDAGF 120

Query: 120 YTLQVIKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWW 179
           YTL VIK NL++EEVT QF V  E PKPSI+SNN NPVE+KD V  TC+PETQNTTYLWW
Sbjct: 121 YTLHVIKENLVNEEVTRQFYVFSEPPKPSITSNNFNPVENKDIVVLTCQPETQNTTYLWW 180

Query: 180 VNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLY 235
           VN QSL VSPRL LS  NRTL LLS T+ND+GPYECEIQNP  A+ SDPVTLNV Y
Sbjct: 181 VNNQSLLVSPRLLLSTDNRTLVLLSATKNDIGPYECEIQNPVGASRSDPVTLNVRY 236



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 49/162 (30%), Positives = 67/162 (41%), Gaps = 10/162 (6%)

Query: 197 NRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTISPSDTYYHAGVNLN 256
           N TL + +VT ND G Y   +      N        V   P  P+I+ ++       ++ 
Sbjct: 105 NGTLLIQNVTHNDAGFYTLHVIKENLVNEEVTRQFYVFSEPPKPSITSNNFNPVENKDIV 164

Query: 257 LSCHAASNPPSQYSWSVNGTFQQYTQKLFIPN--------ITTKNS-GSYACHTTNSATG 307
           +         + Y W VN      + +L +            TKN  G Y C   N   G
Sbjct: 165 VLTCQPETQNTTYLWWVNNQSLLVSPRLLLSTDNRTLVLLSATKNDIGPYECEIQNPV-G 223

Query: 308 RNRTTVRMITVSDALVQGSSPGLSARATVSIMIGVLARVALI 349
            +R+    + V    VQ SSP LSA   VSIMIGVLA +ALI
Sbjct: 224 ASRSDPVTLNVRYESVQASSPDLSAGTAVSIMIGVLAGMALI 265


>gi|194328710 pregnancy specific beta-1-glycoprotein 8 isoform b
           [Homo sapiens]
          Length = 419

 Score =  301 bits (770), Expect = 7e-82
 Identities = 163/319 (51%), Positives = 206/319 (64%), Gaps = 13/319 (4%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MG +SAP C  RI W+GLLLTASL  FWNPPTTAQ+TIEA P+  +EGK+VLLLVHNLPQ
Sbjct: 1   MGLLSAPPCTQRITWKGLLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
           +  GY WYKG+  D    I  YV+  Q I  GPAYS RETIY NASLL++NVT+ D GSY
Sbjct: 61  NLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETIYSNASLLIQNVTQEDAGSY 120

Query: 121 TLQVIKLNLMSEEVTGQ--FSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLW 178
           TL +I     +  VTG   F+++ ETPKPSISS+  NP E  +AV+ TC+PET + +YLW
Sbjct: 121 TLHIIMGGDENRGVTGHFTFTLYLETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLW 180

Query: 179 WVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPD 238
           W+NGQSLP+S RLQLS  NRTL LL VT+   GPYECEI+NP SA+ SDP TLN+L    
Sbjct: 181 WMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLLPKLP 240

Query: 239 APTISPSDTYYHAGVN-LNLSCHAASNPPSQYSWSVNGTFQQYTQK---------LFIPN 288
            P I+ ++       + LN +C   S   + Y W +NG     + +         L +P+
Sbjct: 241 KPYITINNLKPRENKDVLNFTCEPKSENYT-YIWWLNGQSLPVSPRVKRPIENRILILPS 299

Query: 289 ITTKNSGSYACHTTNSATG 307
           +T   +G Y C   +   G
Sbjct: 300 VTRNETGPYQCEIRDQYGG 318



 Score =  226 bits (575), Expect = 3e-59
 Identities = 128/299 (42%), Positives = 173/299 (57%), Gaps = 24/299 (8%)

Query: 25  FTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQDPRGYNWY-KGETVDANRRIIGYV 83
           FTF     T + +I +   N  E  E + L  +       Y W+  G+++  + R+    
Sbjct: 138 FTFTLYLETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRL---- 193

Query: 84  ISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSYTLQVIKLNLMSEEVTGQFSVH-- 141
                          +    N +L +  VT+   G Y  ++   N +S   +  F+++  
Sbjct: 194 ---------------QLSETNRTLFLLGVTKYTAGPYECEI--RNPVSASRSDPFTLNLL 236

Query: 142 PETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLT 201
           P+ PKP I+ NN  P E+KD + FTCEP+++N TY+WW+NGQSLPVSPR++    NR L 
Sbjct: 237 PKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILI 296

Query: 202 LLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTISPSDTYYHAGVNLNLSCHA 261
           L SVTRN+ GPY+CEI++      S PVTLNVLYGPD P I PS TYY +G  L LSC A
Sbjct: 297 LPSVTRNETGPYQCEIRDQYGGIRSYPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSA 356

Query: 262 ASNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYACHTTNSATGRNRTTVRMITVSD 320
            SNPP+QYSW++NG FQ   QKLFIP ITTK+SG YAC   NSATG+  +    + VSD
Sbjct: 357 DSNPPAQYSWTINGKFQLSGQKLFIPQITTKHSGLYACSVRNSATGKESSKSMTVKVSD 415


>gi|51510887 pregnancy specific beta-1-glycoprotein 8 isoform a
           [Homo sapiens]
          Length = 426

 Score =  301 bits (770), Expect = 7e-82
 Identities = 163/319 (51%), Positives = 206/319 (64%), Gaps = 13/319 (4%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MG +SAP C  RI W+GLLLTASL  FWNPPTTAQ+TIEA P+  +EGK+VLLLVHNLPQ
Sbjct: 1   MGLLSAPPCTQRITWKGLLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
           +  GY WYKG+  D    I  YV+  Q I  GPAYS RETIY NASLL++NVT+ D GSY
Sbjct: 61  NLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETIYSNASLLIQNVTQEDAGSY 120

Query: 121 TLQVIKLNLMSEEVTGQ--FSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLW 178
           TL +I     +  VTG   F+++ ETPKPSISS+  NP E  +AV+ TC+PET + +YLW
Sbjct: 121 TLHIIMGGDENRGVTGHFTFTLYLETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLW 180

Query: 179 WVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPD 238
           W+NGQSLP+S RLQLS  NRTL LL VT+   GPYECEI+NP SA+ SDP TLN+L    
Sbjct: 181 WMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLLPKLP 240

Query: 239 APTISPSDTYYHAGVN-LNLSCHAASNPPSQYSWSVNGTFQQYTQK---------LFIPN 288
            P I+ ++       + LN +C   S   + Y W +NG     + +         L +P+
Sbjct: 241 KPYITINNLKPRENKDVLNFTCEPKSENYT-YIWWLNGQSLPVSPRVKRPIENRILILPS 299

Query: 289 ITTKNSGSYACHTTNSATG 307
           +T   +G Y C   +   G
Sbjct: 300 VTRNETGPYQCEIRDQYGG 318



 Score =  224 bits (571), Expect = 9e-59
 Identities = 132/321 (41%), Positives = 179/321 (55%), Gaps = 35/321 (10%)

Query: 25  FTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQDPRGYNWY-KGETVDANRRIIGYV 83
           FTF     T + +I +   N  E  E + L  +       Y W+  G+++  + R+    
Sbjct: 138 FTFTLYLETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRL---- 193

Query: 84  ISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSYTLQVIKLNLMSEEVTGQFSVH-- 141
                          +    N +L +  VT+   G Y  ++   N +S   +  F+++  
Sbjct: 194 ---------------QLSETNRTLFLLGVTKYTAGPYECEI--RNPVSASRSDPFTLNLL 236

Query: 142 PETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLT 201
           P+ PKP I+ NN  P E+KD + FTCEP+++N TY+WW+NGQSLPVSPR++    NR L 
Sbjct: 237 PKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILI 296

Query: 202 LLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTISPSDTYYHAGVNLNLSCHA 261
           L SVTRN+ GPY+CEI++      S PVTLNVLYGPD P I PS TYY +G  L LSC A
Sbjct: 297 LPSVTRNETGPYQCEIRDQYGGIRSYPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSA 356

Query: 262 ASNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYACHTTNSATGRNRTTVRMITVSDA 321
            SNPP+QYSW++NG FQ   QKLFIP ITTK+SG YAC   NSATG+  +    + VS  
Sbjct: 357 DSNPPAQYSWTINGKFQLSGQKLFIPQITTKHSGLYACSVRNSATGKESSKSMTVKVS-- 414

Query: 322 LVQGSSPGLSARATVSIMIGV 342
                      R  VS+ IG+
Sbjct: 415 ---------GKRIPVSLAIGI 426


>gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens]
          Length = 426

 Score =  300 bits (769), Expect = 1e-81
 Identities = 161/311 (51%), Positives = 206/311 (66%), Gaps = 13/311 (4%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MG +SAP C  RI W+GLLLTASL  FWN PTTAQ+TIEA P+  +EGK+VLLLVHNLPQ
Sbjct: 1   MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
           +  GY WYKG+  D    I  YV+  + I  GPAYS RET Y NASLL++NVTR D GSY
Sbjct: 61  NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY 120

Query: 121 TLQVIKLNLMSEEVTGQ--FSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLW 178
           TL +IK +  +  VTG+  F++H ETPKPSISS+N NP E  +AV+ TC+PET + +YLW
Sbjct: 121 TLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLW 180

Query: 179 WVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPD 238
           W+NGQSLP++  L+LS  NRTL LL VT+   GPYECEI+NP SA+ SDPVTLN+L    
Sbjct: 181 WMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP 240

Query: 239 APTISPSDTYYHAGVN-LNLSCHAASNPPSQYSWSVNGTFQQYTQK---------LFIPN 288
            P I+ ++       + LN +C   S   + Y W +NG     + +         L +P+
Sbjct: 241 KPYITINNLNPRENKDVLNFTCEPKSENYT-YIWWLNGQSLPVSPRVKRPIENRILILPS 299

Query: 289 ITTKNSGSYAC 299
           +T   +G Y C
Sbjct: 300 VTRNETGPYQC 310



 Score =  221 bits (562), Expect = 1e-57
 Identities = 112/223 (50%), Positives = 144/223 (64%)

Query: 104 NASLLMRNVTRNDTGSYTLQVIKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDAV 163
           N +L +  VT+   G Y  ++      S       ++ P+ PKP I+ NN NP E+KD +
Sbjct: 199 NRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLPKPYITINNLNPRENKDVL 258

Query: 164 AFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASA 223
            FTCEP+++N TY+WW+NGQSLPVSPR++    NR L L SVTRN+ GPY+CEI++    
Sbjct: 259 NFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGG 318

Query: 224 NFSDPVTLNVLYGPDAPTISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQK 283
             SDPVTLNVLYGPD P I PS TYY +G  L LSC A SNPP+QYSW++N  FQ   QK
Sbjct: 319 IRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINEKFQLPGQK 378

Query: 284 LFIPNITTKNSGSYACHTTNSATGRNRTTVRMITVSDALVQGS 326
           LFI +ITTK+SG Y C   NSATG+  +    + VS   +  S
Sbjct: 379 LFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSGKWIPAS 421


>gi|157805480 pregnancy specific beta-1-glycoprotein 7 precursor
           [Homo sapiens]
          Length = 419

 Score =  300 bits (768), Expect = 1e-81
 Identities = 156/310 (50%), Positives = 201/310 (64%), Gaps = 11/310 (3%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MGP+SAP C   I W+GLLLTASL  FWNPPTTAQ+TIEA P   +EGK+VLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
           +  GY WYKG+  D    +  Y++  Q I  GPAYS RET+Y NASLL++NVT+ DTGSY
Sbjct: 61  NLTGYIWYKGQIRDLYHYVTSYIVDGQIIKYGPAYSGRETVYSNASLLIQNVTQEDTGSY 120

Query: 121 TLQVIKLNLMSEEVTGQ--FSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLW 178
           TL +IK    +  VTG+  F+++ ETPKPSISS+N NP E  +AV  TC+PET + +YLW
Sbjct: 121 TLHIIKRGDGTGGVTGRFTFTLYLETPKPSISSSNFNPREATEAVILTCDPETPDASYLW 180

Query: 179 WVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPD 238
           W+NGQSLP++  LQLS  NRTL L  VT    GPYECEI+NP SA+ SDPVTLN+L    
Sbjct: 181 WMNGQSLPMTHSLQLSETNRTLYLFGVTNYTAGPYECEIRNPVSASRSDPVTLNLLPKLP 240

Query: 239 APTISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQK---------LFIPNI 289
            P I+ ++       +++       +    Y W +NG     + +         L +P++
Sbjct: 241 KPYITINNLNPRENKDVSTFTCEPKSENYTYIWWLNGQSLPVSPRVKRRIENRILILPSV 300

Query: 290 TTKNSGSYAC 299
           T   +G Y C
Sbjct: 301 TRNETGPYQC 310



 Score =  232 bits (591), Expect = 4e-61
 Identities = 130/296 (43%), Positives = 169/296 (57%), Gaps = 18/296 (6%)

Query: 25  FTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQDPRGYNWYKGETVDANRRIIGYVI 84
           FTF     T + +I +   N  E  E ++L  +       Y W+               +
Sbjct: 138 FTFTLYLETPKPSISSSNFNPREATEAVILTCDPETPDASYLWW---------------M 182

Query: 85  SNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSYTLQVIKLNLMSEEVTGQFSVHPET 144
           + Q +    +    ET   N +L +  VT    G Y  ++      S       ++ P+ 
Sbjct: 183 NGQSLPMTHSLQLSET---NRTLYLFGVTNYTAGPYECEIRNPVSASRSDPVTLNLLPKL 239

Query: 145 PKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLS 204
           PKP I+ NN NP E+KD   FTCEP+++N TY+WW+NGQSLPVSPR++    NR L L S
Sbjct: 240 PKPYITINNLNPRENKDVSTFTCEPKSENYTYIWWLNGQSLPVSPRVKRRIENRILILPS 299

Query: 205 VTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTISPSDTYYHAGVNLNLSCHAASN 264
           VTRN+ GPY+CEI++      SDPVTLNVLYGPD P I PS TYYH+G NL LSC A SN
Sbjct: 300 VTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYHSGQNLYLSCFADSN 359

Query: 265 PPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYACHTTNSATGRNRTTVRMITVSD 320
           PP+QYSW++NG FQ   QKL IP ITTK+SG YAC   NSATG+  +    + VSD
Sbjct: 360 PPAQYSWTINGKFQLSGQKLSIPQITTKHSGLYACSVRNSATGKESSKSVTVRVSD 415


>gi|42560235 pregnancy specific beta-1-glycoprotein 4 isoform 1
           [Homo sapiens]
          Length = 419

 Score =  296 bits (759), Expect = 1e-80
 Identities = 158/311 (50%), Positives = 200/311 (64%), Gaps = 13/311 (4%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MGP+SAP C  RI W+G+LLTASL  FWNPPTTAQ+TIEA P   +EGK+VLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTQRITWKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
           +  GY WYKG+       I  YV+  Q+I  GPAYS RE +Y NASLL++NVT+ D GSY
Sbjct: 61  NLAGYIWYKGQMTYLYHYITSYVVDGQRIIYGPAYSGRERVYSNASLLIQNVTQEDAGSY 120

Query: 121 TLQVIKLNLMSEEVTGQ--FSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLW 178
           TL +IK    +  VTG   F++H ETPKPSISS+N NP E  +AV  TC+P T   +Y W
Sbjct: 121 TLHIIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAMEAVILTCDPATPAASYQW 180

Query: 179 WVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPD 238
           W+NGQSLP++ RLQLS  NRTL +  VT+   GPYECEI+NP SA+ SDPVTLN+L    
Sbjct: 181 WMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLS 240

Query: 239 APTISPSDTYYHAGVN-LNLSCHAASNPPSQYSWSVNGTFQQYTQK---------LFIPN 288
            P I+ ++       + L  +C   S   + Y W +NG     + +         L +PN
Sbjct: 241 KPYITINNLNPRENKDVLTFTCEPKSKNYT-YIWWLNGQSLPVSPRVKRPIENRILILPN 299

Query: 289 ITTKNSGSYAC 299
           +T   +G Y C
Sbjct: 300 VTRNETGPYQC 310



 Score =  225 bits (573), Expect = 5e-59
 Identities = 125/297 (42%), Positives = 169/297 (56%), Gaps = 20/297 (6%)

Query: 25  FTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQDPRGYNWY-KGETVDANRRIIGYV 83
           FTF     T + +I +   N  E  E ++L  +       Y W+  G+++    R+    
Sbjct: 138 FTFTLHLETPKPSISSSNLNPREAMEAVILTCDPATPAASYQWWMNGQSLPMTHRL---- 193

Query: 84  ISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSYTLQVIKLNLMSEEVTGQFSVHPE 143
                          +    N +L +  VT+   G Y  ++      S       ++ P+
Sbjct: 194 ---------------QLSKTNRTLFIFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPK 238

Query: 144 TPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLL 203
             KP I+ NN NP E+KD + FTCEP+++N TY+WW+NGQSLPVSPR++    NR L L 
Sbjct: 239 LSKPYITINNLNPRENKDVLTFTCEPKSKNYTYIWWLNGQSLPVSPRVKRPIENRILILP 298

Query: 204 SVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTISPSDTYYHAGVNLNLSCHAAS 263
           +VTRN+ GPY+CEI++      SDPVTLNVLYGPD P+I PS TYY +G NL LSC A S
Sbjct: 299 NVTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPSIYPSFTYYRSGENLYLSCFAES 358

Query: 264 NPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYACHTTNSATGRNRTTVRMITVSD 320
           NP +QYSW++NG FQ   QKL IP ITTK+SG YAC   NSATG+  +    + VSD
Sbjct: 359 NPRAQYSWTINGKFQLSGQKLSIPQITTKHSGLYACSVRNSATGKESSKSITVKVSD 415


>gi|156616284 pregnancy specific beta-1-glycoprotein 9 [Homo
           sapiens]
          Length = 426

 Score =  294 bits (753), Expect = 7e-80
 Identities = 158/311 (50%), Positives = 201/311 (64%), Gaps = 13/311 (4%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MGP+ APSC  RI W+GLLLTASL  FWNPPTTA++TIEA P   +EGK+VLLLVHNLPQ
Sbjct: 1   MGPLPAPSCTQRITWKGLLLTASLLNFWNPPTTAEVTIEAQPPKVSEGKDVLLLVHNLPQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
           +  GY WYKGE  D    II Y++  + I  GPAYS RET+Y NASLL++NVTR D G+Y
Sbjct: 61  NLPGYFWYKGEMTDLYHYIISYIVDGKIIIYGPAYSGRETVYSNASLLIQNVTRKDAGTY 120

Query: 121 TLQVIKLNLMSEEVTGQ--FSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLW 178
           TL +IK    + E      F+++ ETPKP ISS+N NP E  +AV   C+PET + +YLW
Sbjct: 121 TLHIIKRGDETREEIRHFTFTLYLETPKPYISSSNLNPREAMEAVRLICDPETLDASYLW 180

Query: 179 WVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPD 238
           W+NGQSLPV+ RLQLS  NRTL L  VT+   GPYECEI+NP SA+ SDPVTLN+L    
Sbjct: 181 WMNGQSLPVTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP 240

Query: 239 APTISPSDTYYHAGVN-LNLSCHAASNPPSQYSWSVNGTFQQYT---------QKLFIPN 288
            P I+ ++       + L  +C   S   + Y W +NG     +         + L +P+
Sbjct: 241 IPYITINNLNPRENKDVLAFTCEPKSENYT-YIWWLNGQSLPVSPGVKRPIENRILILPS 299

Query: 289 ITTKNSGSYAC 299
           +T   +G Y C
Sbjct: 300 VTRNETGPYQC 310



 Score =  216 bits (550), Expect = 2e-56
 Identities = 108/216 (50%), Positives = 141/216 (65%)

Query: 104 NASLLMRNVTRNDTGSYTLQVIKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDAV 163
           N +L +  VT+   G Y  ++      S       ++ P+ P P I+ NN NP E+KD +
Sbjct: 199 NRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPIPYITINNLNPRENKDVL 258

Query: 164 AFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASA 223
           AFTCEP+++N TY+WW+NGQSLPVSP ++    NR L L SVTRN+ GPY+CEI++    
Sbjct: 259 AFTCEPKSENYTYIWWLNGQSLPVSPGVKRPIENRILILPSVTRNETGPYQCEIRDRYGG 318

Query: 224 NFSDPVTLNVLYGPDAPTISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQK 283
             S+PV LNVLYGPD P I PS TYY +G NL+LSC   SNPP++Y W++NG FQQ  QK
Sbjct: 319 LRSNPVILNVLYGPDLPRIYPSFTYYRSGENLDLSCFTESNPPAEYFWTINGKFQQSGQK 378

Query: 284 LFIPNITTKNSGSYACHTTNSATGRNRTTVRMITVS 319
           LFIP IT  +SG YAC   NSATG+  +    + VS
Sbjct: 379 LFIPQITRNHSGLYACSVHNSATGKEISKSMTVKVS 414


>gi|109240546 pregnancy specific beta-1-glycoprotein 3 [Homo
           sapiens]
          Length = 428

 Score =  293 bits (749), Expect = 2e-79
 Identities = 156/311 (50%), Positives = 201/311 (64%), Gaps = 13/311 (4%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MGP+SAP C  RI W+GLLLTA L  FWN PTTAQ+TIEA P+  ++GK+VLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTQRITWKGLLLTALLLNFWNLPTTAQVTIEAEPTKVSKGKDVLLLVHNLPQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
           +  GY WYKG+  D    I  YV+  Q I  GPAYS RET+Y NASLL++NVTR D GSY
Sbjct: 61  NLAGYIWYKGQMKDLYHYITSYVVDGQIIIYGPAYSGRETVYSNASLLIQNVTREDAGSY 120

Query: 121 TLQVIKLNLMSEEVTGQ--FSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLW 178
           TL ++K    +   TG   F+++ ETPKPSISS+N  P ED +AV+ TC+PET + +YLW
Sbjct: 121 TLHIVKRGDGTRGETGHFTFTLYLETPKPSISSSNLYPREDMEAVSLTCDPETPDASYLW 180

Query: 179 WVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPD 238
           W+NGQSLP++  LQLS   RTL L  VT+   GPYECEI+NP SA+ SDPVTLN+L    
Sbjct: 181 WMNGQSLPMTHSLQLSKNKRTLFLFGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP 240

Query: 239 APTISPSDTYYHAGVN-LNLSCHAASNPPSQYSWSVNGTFQQYTQK---------LFIPN 288
            P I+ ++       + L  +C   S   + Y W +NG     + +         L +P+
Sbjct: 241 KPYITINNLNPRENKDVLAFTCEPKSENYT-YIWWLNGQSLPVSPRVKRPIENRILILPS 299

Query: 289 ITTKNSGSYAC 299
           +T   +G Y C
Sbjct: 300 VTRNETGPYQC 310



 Score =  235 bits (599), Expect = 5e-62
 Identities = 119/226 (52%), Positives = 149/226 (65%)

Query: 106 SLLMRNVTRNDTGSYTLQVIKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDAVAF 165
           +L +  VT+   G Y  ++      S       ++ P+ PKP I+ NN NP E+KD +AF
Sbjct: 201 TLFLFGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLPKPYITINNLNPRENKDVLAF 260

Query: 166 TCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANF 225
           TCEP+++N TY+WW+NGQSLPVSPR++    NR L L SVTRN+ GPY+CEIQ+      
Sbjct: 261 TCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIQDRYGGIR 320

Query: 226 SDPVTLNVLYGPDAPTISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQKLF 285
           S PVTLNVLYGPD P I PS TYYH+G NL LSC A SNPP++YSW++NG FQ   QKLF
Sbjct: 321 SYPVTLNVLYGPDLPRIYPSFTYYHSGENLYLSCFADSNPPAEYSWTINGKFQLSGQKLF 380

Query: 286 IPNITTKNSGSYACHTTNSATGRNRTTVRMITVSDALVQGSSPGLS 331
           IP ITTK+SG YAC   NSATG   +    + VS     G  PGL+
Sbjct: 381 IPQITTKHSGLYACSVRNSATGMESSKSMTVKVSAPSGTGHLPGLN 426



 Score = 35.4 bits (80), Expect = 0.077
 Identities = 40/157 (25%), Positives = 69/157 (43%), Gaps = 28/157 (17%)

Query: 104 NASLLMRNVTRNDTGSYTLQVIKL--NLMSEEVTGQFSVHPETPK--PSISSNNSNPVED 159
           N  L++ +VTRN+TG Y  ++      + S  VT      P+ P+  PS +  +S     
Sbjct: 292 NRILILPSVTRNETGPYQCEIQDRYGGIRSYPVTLNVLYGPDLPRIYPSFTYYHSG---- 347

Query: 160 KDAVAFTCEPETQ-NTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQ 218
            + +  +C  ++     Y W +NG       + QLS   + L +  +T    G Y C ++
Sbjct: 348 -ENLYLSCFADSNPPAEYSWTING-------KFQLS--GQKLFIPQITTKHSGLYACSVR 397

Query: 219 NPASA-NFSDPVTLNVLYGPDAPTISPSDTYYHAGVN 254
           N A+    S  +T+ V         +PS T +  G+N
Sbjct: 398 NSATGMESSKSMTVKV--------SAPSGTGHLPGLN 426


>gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [Homo
           sapiens]
          Length = 435

 Score =  283 bits (724), Expect = 2e-76
 Identities = 157/311 (50%), Positives = 199/311 (63%), Gaps = 14/311 (4%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MGP+SAP C   I W+GLLLTASL  FWN PTTAQ+ IEA P   +EGK+VLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
           +  GY WYKG+  D    I  YV+  Q I  GPAYS RET+Y NASLL++NVT+ D GSY
Sbjct: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQ-IIYGPAYSGRETVYSNASLLIQNVTQEDAGSY 119

Query: 121 TLQVIKLNLMSEEVTGQFSV--HPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLW 178
           TL +IK    +  VTG F+V  + ETPKPSISS+N NP E  +AV   C+PET + +YLW
Sbjct: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179

Query: 179 WVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPD 238
            +NGQ+LP++ RLQLS  NRTL L  VT+   GPYECEI+NP SA+ SDPVTLN+L    
Sbjct: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP 239

Query: 239 APTISPSDTYYHAGVN-LNLSCHAASNPPSQYSWSVNGTFQQYTQK---------LFIPN 288
            P I+ ++       + L  +C   S   + Y W +NG     + +         L +P+
Sbjct: 240 MPYITINNLNPREKKDVLAFTCEPKSRNYT-YIWWLNGQSLPVSPRVKRPIENRILILPS 298

Query: 289 ITTKNSGSYAC 299
           +T   +G Y C
Sbjct: 299 VTRNETGPYQC 309


>gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b
           [Homo sapiens]
          Length = 424

 Score =  283 bits (724), Expect = 2e-76
 Identities = 157/311 (50%), Positives = 199/311 (63%), Gaps = 14/311 (4%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MGP+SAP C   I W+GLLLTASL  FWN PTTAQ+ IEA P   +EGK+VLLLVHNLPQ
Sbjct: 1   MGPLSAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
           +  GY WYKG+  D    I  YV+  Q I  GPAYS RET+Y NASLL++NVT+ D GSY
Sbjct: 61  NLTGYIWYKGQMTDLYHYITSYVVHGQ-IIYGPAYSGRETVYSNASLLIQNVTQEDAGSY 119

Query: 121 TLQVIKLNLMSEEVTGQFSV--HPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLW 178
           TL +IK    +  VTG F+V  + ETPKPSISS+N NP E  +AV   C+PET + +YLW
Sbjct: 120 TLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLW 179

Query: 179 WVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPD 238
            +NGQ+LP++ RLQLS  NRTL L  VT+   GPYECEI+NP SA+ SDPVTLN+L    
Sbjct: 180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLP 239

Query: 239 APTISPSDTYYHAGVN-LNLSCHAASNPPSQYSWSVNGTFQQYTQK---------LFIPN 288
            P I+ ++       + L  +C   S   + Y W +NG     + +         L +P+
Sbjct: 240 MPYITINNLNPREKKDVLAFTCEPKSRNYT-YIWWLNGQSLPVSPRVKRPIENRILILPS 298

Query: 289 ITTKNSGSYAC 299
           +T   +G Y C
Sbjct: 299 VTRNETGPYQC 309



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 17/123 (13%)

Query: 104 NASLLMRNVTRNDTGSYTLQVIKL--NLMSEEVTGQFSVHPETPK--PSISSNNSNPVED 159
           N  L++ +VTRN+TG Y  ++      + S  VT      P+ P+  PS +   S    D
Sbjct: 291 NRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLD 350

Query: 160 KDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQN 219
               A +  P      Y W +NG       + QLS   + L +  +T N  G Y C ++N
Sbjct: 351 LSCFADSNPP----AEYSWTING-------KFQLSG--QKLFIPQITTNHSGLYACSVRN 397

Query: 220 PAS 222
            A+
Sbjct: 398 SAT 400


>gi|194328712 pregnancy specific beta-1-glycoprotein 8 isoform c
           [Homo sapiens]
          Length = 297

 Score =  244 bits (623), Expect = 8e-65
 Identities = 139/323 (43%), Positives = 186/323 (57%), Gaps = 33/323 (10%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MG +SAP C  RI W+GLLLT           T + +I +   N  E  E + L  +   
Sbjct: 1   MGLLSAPPCTQRITWKGLLLTVE---------TPKPSISSSKLNPREAMEAVSLTCDPET 51

Query: 61  DPRGYNWY-KGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGS 119
               Y W+  G+++  + R+                   +    N +L +  VT+   G 
Sbjct: 52  PDASYLWWMNGQSLPMSHRL-------------------QLSETNRTLFLLGVTKYTAGP 92

Query: 120 YTLQVIKLNLMSEEVTGQFSVH--PETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYL 177
           Y  ++   N +S   +  F+++  P+ PKP I+ NN  P E+KD + FTCEP+++N TY+
Sbjct: 93  YECEI--RNPVSASRSDPFTLNLLPKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYI 150

Query: 178 WWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGP 237
           WW+NGQSLPVSPR++    NR L L SVTRN+ GPY+CEI++      S PVTLNVLYGP
Sbjct: 151 WWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNVLYGP 210

Query: 238 DAPTISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSY 297
           D P I PS TYY +G  L LSC A SNPP+QYSW++NG FQ   QKLFIP ITTK+SG Y
Sbjct: 211 DLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINGKFQLSGQKLFIPQITTKHSGLY 270

Query: 298 ACHTTNSATGRNRTTVRMITVSD 320
           AC   NSATG+  +    + VSD
Sbjct: 271 ACSVRNSATGKESSKSMTVKVSD 293


>gi|164663826 pregnancy specific beta-1-glycoprotein 11 isoform 2
           [Homo sapiens]
          Length = 213

 Score =  220 bits (560), Expect = 2e-57
 Identities = 107/176 (60%), Positives = 128/176 (72%)

Query: 143 ETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTL 202
           ETPKPSISS+N NP E  + V  TC PET + +YLWW+NGQSLP++ R+QLS  NRTL L
Sbjct: 23  ETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFL 82

Query: 203 LSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTISPSDTYYHAGVNLNLSCHAA 262
             VT+   GPYECEI N  SA+ SDPVTLN+L+GPD P I PS T Y++G NL+LSC A 
Sbjct: 83  FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDLSCFAN 142

Query: 263 SNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYACHTTNSATGRNRTTVRMITV 318
           SNPP+QYSW++NG FQ   QKLFIP IT K++G YAC   NSATG   +T   I V
Sbjct: 143 SNPPAQYSWTINGKFQLSGQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRV 198



 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 62/249 (24%), Positives = 97/249 (38%), Gaps = 47/249 (18%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MGP+SAP C   I W+GLLLT           T + +I +   N  E  E ++L  N   
Sbjct: 1   MGPLSAPPCTEHIKWKGLLLTVE---------TPKPSISSSNLNPREAMETVILTCNPET 51

Query: 61  DPRGYNWY-KGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGS 119
               Y W+  G+++    R+                   +    N +L +  VT+   G 
Sbjct: 52  PDASYLWWMNGQSLPMTHRM-------------------QLSETNRTLFLFGVTKYTAGP 92

Query: 120 YTLQVIKLN--LMSEEVTGQFSVHPETPK--PSISSNNSNPVEDKDAVAFTCEPETQNTT 175
           Y  ++        S+ VT      P+ P+  PS++S  S    D    A +  P      
Sbjct: 93  YECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDLSCFANSNPP----AQ 148

Query: 176 YLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASA-NFSDPVTLNVL 234
           Y W +NG       + QLS   + L +  +T    G Y C  +N A+    S  +T+ V+
Sbjct: 149 YSWTING-------KFQLS--GQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRVI 199

Query: 235 YGPDAPTIS 243
             P   T +
Sbjct: 200 APPGLGTFA 208


>gi|164663824 pregnancy specific beta-1-glycoprotein 11 isoform 2
           [Homo sapiens]
          Length = 213

 Score =  220 bits (560), Expect = 2e-57
 Identities = 107/176 (60%), Positives = 128/176 (72%)

Query: 143 ETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTL 202
           ETPKPSISS+N NP E  + V  TC PET + +YLWW+NGQSLP++ R+QLS  NRTL L
Sbjct: 23  ETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFL 82

Query: 203 LSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTISPSDTYYHAGVNLNLSCHAA 262
             VT+   GPYECEI N  SA+ SDPVTLN+L+GPD P I PS T Y++G NL+LSC A 
Sbjct: 83  FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDLSCFAN 142

Query: 263 SNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYACHTTNSATGRNRTTVRMITV 318
           SNPP+QYSW++NG FQ   QKLFIP IT K++G YAC   NSATG   +T   I V
Sbjct: 143 SNPPAQYSWTINGKFQLSGQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRV 198



 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 62/249 (24%), Positives = 97/249 (38%), Gaps = 47/249 (18%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MGP+SAP C   I W+GLLLT           T + +I +   N  E  E ++L  N   
Sbjct: 1   MGPLSAPPCTEHIKWKGLLLTVE---------TPKPSISSSNLNPREAMETVILTCNPET 51

Query: 61  DPRGYNWY-KGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGS 119
               Y W+  G+++    R+                   +    N +L +  VT+   G 
Sbjct: 52  PDASYLWWMNGQSLPMTHRM-------------------QLSETNRTLFLFGVTKYTAGP 92

Query: 120 YTLQVIKLN--LMSEEVTGQFSVHPETPK--PSISSNNSNPVEDKDAVAFTCEPETQNTT 175
           Y  ++        S+ VT      P+ P+  PS++S  S    D    A +  P      
Sbjct: 93  YECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDLSCFANSNPP----AQ 148

Query: 176 YLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASA-NFSDPVTLNVL 234
           Y W +NG       + QLS   + L +  +T    G Y C  +N A+    S  +T+ V+
Sbjct: 149 YSWTING-------KFQLS--GQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRVI 199

Query: 235 YGPDAPTIS 243
             P   T +
Sbjct: 200 APPGLGTFA 208


>gi|52317156 carcinoembryonic antigen-related cell adhesion molecule
           isoform 2 [Homo sapiens]
          Length = 292

 Score =  206 bits (525), Expect = 2e-53
 Identities = 111/235 (47%), Positives = 140/235 (59%), Gaps = 1/235 (0%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MGP SA   R  IPWQGLLLTASL TFWN PTTA L I + P   AEG+ V L V  LP+
Sbjct: 1   MGPPSACPHRECIPWQGLLLTASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPE 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
           +   Y WYKG+TV+ N+ I  YVI     TPGPAYS RETI P+  L  +NVT  DTG Y
Sbjct: 61  NLYSYGWYKGKTVEPNQLIAAYVIDTHVRTPGPAYSGRETISPSGDLHFQNVTLEDTGYY 120

Query: 121 TLQVIKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWV 180
            LQV   N   E+ +    V+    +PSI + +S  V +K +V  TC      T++ W  
Sbjct: 121 NLQVTYRNSQIEQASHHLRVYESVAQPSIQA-SSTTVTEKGSVVLTCHTNNTGTSFQWIF 179

Query: 181 NGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLY 235
           N Q L V+ R++LS  N  LT+  + + D G Y+CE+ NP S+N SDP+ L V Y
Sbjct: 180 NNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLKLTVKY 234


>gi|148612793 carcinoembryonic antigen-related cell adhesion
           molecule isoform 1 [Homo sapiens]
          Length = 293

 Score =  204 bits (520), Expect = 7e-53
 Identities = 110/233 (47%), Positives = 139/233 (59%), Gaps = 1/233 (0%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MGP SA   R  IPWQGLLLTASL TFWN PTTA L I + P   AEG+ V L V  LP+
Sbjct: 1   MGPPSACPHRECIPWQGLLLTASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPE 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
           +   Y WYKG+TV+ N+ I  YVI     TPGPAYS RETI P+  L  +NVT  DTG Y
Sbjct: 61  NLYSYGWYKGKTVEPNQLIAAYVIDTHVRTPGPAYSGRETISPSGDLHFQNVTLEDTGYY 120

Query: 121 TLQVIKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWV 180
            LQV   N   E+ +    V+    +PSI + +S  V +K +V  TC      T++ W  
Sbjct: 121 NLQVTYRNSQIEQASHHLRVYESVAQPSIQA-SSTTVTEKGSVVLTCHTNNTGTSFQWIF 179

Query: 181 NGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNV 233
           N Q L V+ R++LS  N  LT+  + + D G Y+CE+ NP S+N SDP+ L V
Sbjct: 180 NNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLKLTV 232


>gi|121114300 carcinoembryonic antigen-related cell adhesion
           molecule 3 precursor [Homo sapiens]
          Length = 252

 Score =  202 bits (514), Expect = 4e-52
 Identities = 101/143 (70%), Positives = 114/143 (79%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MGP SA   R  IPWQGLLLTASL  FWNPPTTA+LTIE++P + AEGKEVLLLVHNLPQ
Sbjct: 1   MGPPSASPHRECIPWQGLLLTASLLNFWNPPTTAKLTIESMPLSVAEGKEVLLLVHNLPQ 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
              GY+WYKGE VD N  I+GYVI  QQ TPG AYS RETIY NASLL++NVT+ND G Y
Sbjct: 61  HLFGYSWYKGERVDGNSLIVGYVIGTQQATPGAAYSGRETIYTNASLLIQNVTQNDIGFY 120

Query: 121 TLQVIKLNLMSEEVTGQFSVHPE 143
           TLQVIK +L++EE TGQF V+ E
Sbjct: 121 TLQVIKSDLVNEEATGQFHVYQE 143



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 20/66 (30%), Positives = 28/66 (42%), Gaps = 5/66 (7%)

Query: 284 LFIPNITTKNSGSYACHTTNSATGRNRTTVRMITVSDALVQGSSPGLSARATVSIMIGVL 343
           L I N+T  + G Y      S       T +       + Q ++PGL   A   I+ GVL
Sbjct: 107 LLIQNVTQNDIGFYTLQVIKSDLVNEEATGQF-----HVYQENAPGLPVGAVAGIVTGVL 161

Query: 344 ARVALI 349
             VAL+
Sbjct: 162 VGVALV 167


>gi|85861202 carcinoembryonic antigen-related cell adhesion molecule
           16 [Homo sapiens]
          Length = 484

 Score =  164 bits (416), Expect = 8e-41
 Identities = 97/314 (30%), Positives = 155/314 (49%), Gaps = 13/314 (4%)

Query: 18  LLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQDPRGYNWYKGETVDANR 77
           LLL+A   TF N      +T+E  P+  +EG  V L+VH L  +   Y+WY G T+  + 
Sbjct: 68  LLLSA---TFLNVGAEISITLE--PAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122

Query: 78  RIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSYTLQVIKLNLMSEEVTGQ 137
            +  Y++S    TPGPA++ RE + P+ SL ++ +    +G+Y LQ     L +E   G 
Sbjct: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGH 182

Query: 138 FSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGN 197
             VH    +P++ +N++  VE +D +   C   +      W+ NG +LPV+ RL LS   
Sbjct: 183 VQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDG 242

Query: 198 RTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTISPSDT-------YYH 250
           R L    + R + G Y+CE+ NP S + S+P+ L V +GP+   I    T          
Sbjct: 243 RVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVD 302

Query: 251 AGVNLNLSCHAASNPPSQYSWSVNG-TFQQYTQKLFIPNITTKNSGSYACHTTNSATGRN 309
              +L L C + S P  +Y W+ NG   +     L I ++T    G+Y C   N+ T  +
Sbjct: 303 FNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLS 362

Query: 310 RTTVRMITVSDALV 323
            +   ++ +S A V
Sbjct: 363 GSASVVVKLSAAAV 376



 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 37/105 (35%), Positives = 58/105 (55%), Gaps = 2/105 (1%)

Query: 38  IEAVPSNAAEGKEVLLLVHNLPQDPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSN 97
           I  VP+   EG++V L V   P+D   Y WY+G   + NR ++  + S   I  GPA++ 
Sbjct: 380 IVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNR-LLSQLPSGTWIA-GPAHTG 437

Query: 98  RETIYPNASLLMRNVTRNDTGSYTLQVIKLNLMSEEVTGQFSVHP 142
           RE  +PN SLL++ +   DTG YTL+ + +   +E +  +  V P
Sbjct: 438 REVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQVAP 482


>gi|71143132 carcinoembryonic antigen-related cell adhesion molecule
           4 [Homo sapiens]
          Length = 244

 Score =  159 bits (402), Expect = 4e-39
 Identities = 77/141 (54%), Positives = 97/141 (68%)

Query: 1   MGPISAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQ 60
           MGP SA       PWQGLL+TASL TFW+PPTT Q TIEA+PS+AAEGK+VLLL  N+ +
Sbjct: 1   MGPPSAAPRGGHRPWQGLLITASLLTFWHPPTTVQFTIEALPSSAAEGKDVLLLACNISE 60

Query: 61  DPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSY 120
             + Y W+KG+T + +  I GY+   Q   PG AYS RET+YPN SLL +N+T  D GSY
Sbjct: 61  TIQAYYWHKGKTAEGSPLIAGYITDIQANIPGAAYSGRETVYPNGSLLFQNITLEDAGSY 120

Query: 121 TLQVIKLNLMSEEVTGQFSVH 141
           TL+ I  +  S++ TGQ  VH
Sbjct: 121 TLRTINASYDSDQATGQLHVH 141



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 5/66 (7%)

Query: 284 LFIPNITTKNSGSYACHTTNSATGRNRTTVRMITVSDALVQGSSPGLSARATVSIMIGVL 343
           L   NIT +++GSY   T N++   ++ T ++      + Q + PGL   A   I+ GVL
Sbjct: 107 LLFQNITLEDAGSYTLRTINASYDSDQATGQL-----HVHQNNVPGLPVGAVAGIVTGVL 161

Query: 344 ARVALI 349
             VAL+
Sbjct: 162 VGVALV 167


>gi|156564378 carcinoembryonic antigen-related cell adhesion
           molecule 20 5L [Homo sapiens]
          Length = 596

 Score =  117 bits (293), Expect = 2e-26
 Identities = 73/210 (34%), Positives = 111/210 (52%), Gaps = 12/210 (5%)

Query: 147 PSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVT 206
           P +  ++ N VE+  +V  TC+   Q+    W+++GQ L  S  LQLS  NRTL +  + 
Sbjct: 256 PQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQ 315

Query: 207 RNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTISP-------SDTYYHAGVNLNLSC 259
           RND GPY CE+ N  S   S+P+ L + YGPD   I+        S        +L L C
Sbjct: 316 RNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQC 375

Query: 260 HAASNPPSQYSWSV-NGTFQQYTQKLFIPNITTKNSGSYACHTTNSATGRNRTTVRMITV 318
            A S P ++Y W++ + T +   ++L I  +T ++ G Y C  +NS TG  R+T  ++ V
Sbjct: 376 WAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV 435

Query: 319 SDALVQGSSPGLSARATVSIMIGVLARVAL 348
               V   S  LS+ A   I+IG+LA +A+
Sbjct: 436 ----VGPQSSSLSSGAIAGIVIGILAVIAV 461



 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 57/172 (33%), Positives = 84/172 (48%), Gaps = 8/172 (4%)

Query: 143 ETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTL 202
           E  KPSI+ +    +E KD V F C  +  N T  W  N  S+    R+QLS   + LT+
Sbjct: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125

Query: 203 LSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTI-------SPSDTYYHAGVNL 255
           L V R D G Y+CE ++   +  SDP+ L+V YGPD   I       S        G ++
Sbjct: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185

Query: 256 NLSCHAASNPPSQYSWSVNGTFQQYTQKLF-IPNITTKNSGSYACHTTNSAT 306
                  S+PP  Y+W +  +   +T + F I  ++ ++ G Y C  +NSAT
Sbjct: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSAT 237



 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 77/335 (22%), Positives = 135/335 (40%), Gaps = 47/335 (14%)

Query: 7   PSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQDPRGYN 66
           P+  W   W G+LL+ASL T W+PP  AQLT+ A P +A + ++V+L V   P+ P+ + 
Sbjct: 3   PADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHG 62

Query: 67  WYK-----------GETVDANRRIIGYVISNQ-QITPGPAYSNRETIYPNASLLMRN--- 111
             +           G  ++    +  Y  +    IT     +N   ++     L ++   
Sbjct: 63  RSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKI 122

Query: 112 -----VTRNDTGSYTLQV--IKLNLMSEEVTGQFSVHPETPKPSISSN--NSNPVEDKDA 162
                V R D+G+Y  +     L+  S+ +       P+  +  + S   +   VE  + 
Sbjct: 123 LTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEG 182

Query: 163 VAFTCEPETQN---TTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQN 219
            + T   ET++     Y W++            LS+  RT T+ +V+R   G Y C + N
Sbjct: 183 SSMTFLAETKSHPPCAYTWFLLDSI--------LSHTTRTFTIHAVSREHEGLYRCLVSN 234

Query: 220 PASANFS-DPVTLNVLYGPDAPTISPSD-TYYHAGVNLNLSCHAASNPPSQYSWSVNG-- 275
            A+   S   + + VL     P + PS         +++L+C    N      W ++G  
Sbjct: 235 SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQP 293

Query: 276 -------TFQQYTQKLFIPNITTKNSGSYACHTTN 303
                        + L I  +   ++G YAC   N
Sbjct: 294 LLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328


>gi|156564393 carcinoembryonic antigen-related cell adhesion
           molecule 20 5S [Homo sapiens]
          Length = 584

 Score =  117 bits (293), Expect = 2e-26
 Identities = 73/210 (34%), Positives = 111/210 (52%), Gaps = 12/210 (5%)

Query: 147 PSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVT 206
           P +  ++ N VE+  +V  TC+   Q+    W+++GQ L  S  LQLS  NRTL +  + 
Sbjct: 256 PQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQ 315

Query: 207 RNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTISP-------SDTYYHAGVNLNLSC 259
           RND GPY CE+ N  S   S+P+ L + YGPD   I+        S        +L L C
Sbjct: 316 RNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQC 375

Query: 260 HAASNPPSQYSWSV-NGTFQQYTQKLFIPNITTKNSGSYACHTTNSATGRNRTTVRMITV 318
            A S P ++Y W++ + T +   ++L I  +T ++ G Y C  +NS TG  R+T  ++ V
Sbjct: 376 WAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV 435

Query: 319 SDALVQGSSPGLSARATVSIMIGVLARVAL 348
               V   S  LS+ A   I+IG+LA +A+
Sbjct: 436 ----VGPQSSSLSSGAIAGIVIGILAVIAV 461



 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 57/172 (33%), Positives = 84/172 (48%), Gaps = 8/172 (4%)

Query: 143 ETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTL 202
           E  KPSI+ +    +E KD V F C  +  N T  W  N  S+    R+QLS   + LT+
Sbjct: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125

Query: 203 LSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTI-------SPSDTYYHAGVNL 255
           L V R D G Y+CE ++   +  SDP+ L+V YGPD   I       S        G ++
Sbjct: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185

Query: 256 NLSCHAASNPPSQYSWSVNGTFQQYTQKLF-IPNITTKNSGSYACHTTNSAT 306
                  S+PP  Y+W +  +   +T + F I  ++ ++ G Y C  +NSAT
Sbjct: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSAT 237



 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 77/335 (22%), Positives = 135/335 (40%), Gaps = 47/335 (14%)

Query: 7   PSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQDPRGYN 66
           P+  W   W G+LL+ASL T W+PP  AQLT+ A P +A + ++V+L V   P+ P+ + 
Sbjct: 3   PADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHG 62

Query: 67  WYK-----------GETVDANRRIIGYVISNQ-QITPGPAYSNRETIYPNASLLMRN--- 111
             +           G  ++    +  Y  +    IT     +N   ++     L ++   
Sbjct: 63  RSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKI 122

Query: 112 -----VTRNDTGSYTLQV--IKLNLMSEEVTGQFSVHPETPKPSISSN--NSNPVEDKDA 162
                V R D+G+Y  +     L+  S+ +       P+  +  + S   +   VE  + 
Sbjct: 123 LTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEG 182

Query: 163 VAFTCEPETQN---TTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQN 219
            + T   ET++     Y W++            LS+  RT T+ +V+R   G Y C + N
Sbjct: 183 SSMTFLAETKSHPPCAYTWFLLDSI--------LSHTTRTFTIHAVSREHEGLYRCLVSN 234

Query: 220 PASANFS-DPVTLNVLYGPDAPTISPSD-TYYHAGVNLNLSCHAASNPPSQYSWSVNG-- 275
            A+   S   + + VL     P + PS         +++L+C    N      W ++G  
Sbjct: 235 SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQP 293

Query: 276 -------TFQQYTQKLFIPNITTKNSGSYACHTTN 303
                        + L I  +   ++G YAC   N
Sbjct: 294 LLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.129    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,526,744
Number of Sequences: 37866
Number of extensions: 680714
Number of successful extensions: 3305
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 142
Number of HSP's successfully gapped in prelim test: 232
Number of HSP's that attempted gapping in prelim test: 1680
Number of HSP's gapped (non-prelim): 1319
length of query: 349
length of database: 18,247,518
effective HSP length: 103
effective length of query: 246
effective length of database: 14,347,320
effective search space: 3529440720
effective search space used: 3529440720
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.