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Search of human proteins with 21264315
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21264315 EH-domain containing 4 [Homo sapiens]
(541 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21264315 EH-domain containing 4 [Homo sapiens] 1083 0.0
gi|30240932 EH-domain containing 1 [Homo sapiens] 827 0.0
gi|7657056 EH-domain containing 3 [Homo sapiens] 824 0.0
gi|21361462 EH-domain containing 2 [Homo sapiens] 745 0.0
gi|149363672 sarcalumenin [Homo sapiens] 210 3e-54
gi|4503593 epidermal growth factor receptor pathway substrate 15... 100 6e-21
gi|10864047 epidermal growth factor receptor pathway substrate 1... 96 8e-20
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 84 4e-16
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 84 4e-16
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 74 4e-13
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 74 4e-13
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 74 4e-13
gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2... 67 3e-11
gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1... 67 3e-11
gi|190886435 RALBP1 associated Eps domain containing 1 isoform a... 67 4e-11
gi|190886437 RALBP1 associated Eps domain containing 1 isoform b... 67 4e-11
gi|105990532 apolipoprotein B precursor [Homo sapiens] 36 0.078
gi|52856430 protein expressed in prostate, ovary, testis, and pl... 33 0.87
gi|40217805 nucleolar protein 9 [Homo sapiens] 33 0.87
gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Hom... 31 2.5
gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo ... 31 2.5
gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo ... 31 2.5
gi|38569411 AP1 gamma subunit binding protein 1 isoform 2 [Homo ... 30 4.3
gi|38569409 AP1 gamma subunit binding protein 1 isoform 1 [Homo ... 30 4.3
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 30 4.3
gi|15487670 nuclear RNA export factor 1 isoform 1 [Homo sapiens] 30 5.6
gi|5803029 ATP/GTP-binding protein isoform 1 [Homo sapiens] 30 5.6
gi|118498356 kinectin 1 isoform a [Homo sapiens] 30 7.3
gi|118498368 kinectin 1 isoform c [Homo sapiens] 30 7.3
gi|33620775 kinectin 1 isoform a [Homo sapiens] 30 7.3
>gi|21264315 EH-domain containing 4 [Homo sapiens]
Length = 541
Score = 1083 bits (2802), Expect = 0.0
Identities = 541/541 (100%), Positives = 541/541 (100%)
Query: 1 MFSWMGRQAGGRERAGGADAVQTVTGGLRSLYLRKVLPLEEAYRFHEFHSPALEDADFEN 60
MFSWMGRQAGGRERAGGADAVQTVTGGLRSLYLRKVLPLEEAYRFHEFHSPALEDADFEN
Sbjct: 1 MFSWMGRQAGGRERAGGADAVQTVTGGLRSLYLRKVLPLEEAYRFHEFHSPALEDADFEN 60
Query: 61 KPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVD 120
KPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVD
Sbjct: 61 KPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVD 120
Query: 121 PKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVLQW 180
PKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVLQW
Sbjct: 121 PKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVLQW 180
Query: 181 FAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALM 240
FAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALM
Sbjct: 181 FAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALM 240
Query: 241 WSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDL 300
WSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDL
Sbjct: 241 WSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDL 300
Query: 301 IKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVK 360
IKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVK
Sbjct: 301 IKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVK 360
Query: 361 AMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQEETSTPTQLVQGGAFDGT 420
AMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQEETSTPTQLVQGGAFDGT
Sbjct: 361 AMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQEETSTPTQLVQGGAFDGT 420
Query: 421 TEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLP 480
TEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLP
Sbjct: 421 TEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLP 480
Query: 481 NSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRKSLPKA 540
NSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRKSLPKA
Sbjct: 481 NSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRKSLPKA 540
Query: 541 D 541
D
Sbjct: 541 D 541
>gi|30240932 EH-domain containing 1 [Homo sapiens]
Length = 534
Score = 827 bits (2137), Expect = 0.0
Identities = 401/535 (74%), Positives = 466/535 (87%), Gaps = 3/535 (0%)
Query: 1 MFSWMGRQAGGRERAGGADAVQTVTGGLRSLYLRKVLPLEEAYRFHEFHSPALEDADFEN 60
MFSW+ + A R + QTV GLR LY +K+LPLEE YRFHEFHSPALEDADF+N
Sbjct: 1 MFSWVSKDA---RRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDN 57
Query: 61 KPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVD 120
KPM+LLVGQYSTGKTTFIR+L+EQDFPGMRIGPEPTTDSFIAVM+G TEG PGNALVVD
Sbjct: 58 KPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVD 117
Query: 121 PKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVLQW 180
P++PFRKL+ FGNAFLNRFMC+QLPN VL SIS+ID+PGILSGEKQRISRGYDF VL+W
Sbjct: 118 PRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEW 177
Query: 181 FAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALM 240
FAERVDRIILLFDAHKLDISDEFSE IKA + +DKIRVVLNKADQ++TQQLMRVYGALM
Sbjct: 178 FAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALM 237
Query: 241 WSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDL 300
WSLGK+INTPEV+RVYIGSFW+ PL DNR+LFEAE QDLF+DIQSLP+ AA+RKLNDL
Sbjct: 238 WSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDL 297
Query: 301 IKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVK 360
IKRARLAKVHAYIIS LKKEMP+VFGKE+KK+EL++ L EIY +++RE+QIS GDFP ++
Sbjct: 298 IKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLR 357
Query: 361 AMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQEETSTPTQLVQGGAFDGT 420
MQE L+ DF+KF +LKPKL++ VD+ML+N I+ LM ++ QEE+ P+Q+V+GGAFDGT
Sbjct: 358 KMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGT 417
Query: 421 TEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLP 480
GPF GYGEGA EG D+ EWVV KDKP YDE+FYTLSP+NGKI+G NAKKEMV SKLP
Sbjct: 418 MNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLP 477
Query: 481 NSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRK 535
N+VLGKIWKLAD D DG+LD+EEFALA HLIK+KL+G+ELP+ LPPHLVPPS R+
Sbjct: 478 NTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRR 532
>gi|7657056 EH-domain containing 3 [Homo sapiens]
Length = 535
Score = 824 bits (2128), Expect = 0.0
Identities = 402/535 (75%), Positives = 465/535 (86%), Gaps = 3/535 (0%)
Query: 1 MFSWMGRQAGGRERAGGADAVQTVTGGLRSLYLRKVLPLEEAYRFHEFHSPALEDADFEN 60
MFSW+G R+ + QTV+ GL+ LY K+LPLEE YRFHEFHSPALEDADF+N
Sbjct: 1 MFSWLGTDDRRRK---DPEVFQTVSEGLKKLYKSKLLPLEEHYRFHEFHSPALEDADFDN 57
Query: 61 KPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVD 120
KPM+LLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVM G+ EG PGNALVVD
Sbjct: 58 KPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDMEGIIPGNALVVD 117
Query: 121 PKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVLQW 180
PKKPFRKL+ FGNAFLNRF+C+QLPN VL+SISVID+PGILSGEKQRISRGYDF VL+W
Sbjct: 118 PKKPFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEW 177
Query: 181 FAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALM 240
FAERVDRIILLFDAHKLDISDEFSE IKA + +DK+RVVLNKADQ++TQQLMRVYGALM
Sbjct: 178 FAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALM 237
Query: 241 WSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDL 300
WSLGK++NTPEV+RVYIGSFW+ PL DNR+LFEAE QDLFRDIQSLP+ AA+RKLNDL
Sbjct: 238 WSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDL 297
Query: 301 IKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVK 360
IKRARLAKVHAYIIS LKKEMPSVFGK+NKK+EL++ L EIY +++RE+QIS GDFP +K
Sbjct: 298 IKRARLAKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPNLK 357
Query: 361 AMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQEETSTPTQLVQGGAFDGT 420
MQ+QL+ DF+KF LK KL+E VD+ML++ I+ LM L+ QEE+ P Q+V+GGAF+GT
Sbjct: 358 RMQDQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPIQMVKGGAFEGT 417
Query: 421 TEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLP 480
GPF GYGEGA EG D+ EWVVA+DKP+YDE+FYTLSP++GKI+G NAKKEMV SKLP
Sbjct: 418 LHGPFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLP 477
Query: 481 NSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRK 535
NSVLGKIWKLAD D DGMLD++EFALA HLIK+KL+G+ELP+ LP HL+PPS RK
Sbjct: 478 NSVLGKIWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRK 532
>gi|21361462 EH-domain containing 2 [Homo sapiens]
Length = 543
Score = 745 bits (1923), Expect = 0.0
Identities = 372/546 (68%), Positives = 443/546 (81%), Gaps = 8/546 (1%)
Query: 1 MFSWMGRQAGGRERAGGADAVQTVTGGLRSLYLRKVLPLEEAYRFHEFHSPALEDADFEN 60
MFSW+ R G R +A++TVT L+ LY K+LPLEE YRF FHSPALEDADF+
Sbjct: 1 MFSWLKR---GGARGQQPEAIRTVTSALKELYRTKLLPLEEHYRFGAFHSPALEDADFDG 57
Query: 61 KPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVD 120
KPM+L+ GQYSTGKT+FI+YLLEQ+ PG R+GPEPTTD F+AVM+G+TEG+ PGNALVVD
Sbjct: 58 KPMVLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGDTEGTVPGNALVVD 117
Query: 121 PKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVLQW 180
P KPFRKL+ FGN FLNRFMC+QLPNQVL+SIS+ID+PGILSG KQR+SRGYDF VL+W
Sbjct: 118 PDKPFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRW 177
Query: 181 FAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALM 240
FAERVD IILLFDAHKL+ISDEFSEAI A RG +DKIRVVLNKAD V+TQQLMRVYGALM
Sbjct: 178 FAERVDLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALM 237
Query: 241 WSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDL 300
W+LGKV+ TPEVLRVYIGSFW+QPL DNRRLFE E QDLFRDIQ LP+ AA+RKLNDL
Sbjct: 238 WALGKVVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDL 297
Query: 301 IKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVK 360
+KRARL +VHAYIISYLKKEMPSVFGKENKK++LI +LP I+ ++Q E+ IS GDFP+ +
Sbjct: 298 VKRARLVRVHAYIISYLKKEMPSVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQ 357
Query: 361 AMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQEETSTPTQLVQGGAFDGT 420
MQE L +DFTKFHSLKPKL+EA+D ML++ I+ LM L+ QEE + VQGGAF+GT
Sbjct: 358 KMQELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESTEVGVQGGAFEGT 417
Query: 421 TEGPF-----NQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMV 475
GPF ++ +G + DE EWVV KDK YDE+FY L+P +GK+SG AK MV
Sbjct: 418 HMGPFVERGPDEAMEDGEEGSDDEAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMV 477
Query: 476 TSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRK 535
+KLPNSVLG+IWKL+D D DGMLD+EEFALA HLI+ KL+G+ LP++LP LVPPS R+
Sbjct: 478 GTKLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRR 537
Query: 536 SLPKAD 541
A+
Sbjct: 538 HKGSAE 543
>gi|149363672 sarcalumenin [Homo sapiens]
Length = 473
Score = 210 bits (534), Expect = 3e-54
Identities = 117/355 (32%), Positives = 192/355 (54%), Gaps = 9/355 (2%)
Query: 18 ADAVQTVTGGLRSLYLRKVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTF 77
+D V LR +Y + PLE++Y+++E + D + +KPM+L +G +S GK+T
Sbjct: 50 SDDYSAVLQRLRKIYHSSIKPLEQSYKYNELRQHEITDGEITSKPMVLFLGPWSVGKSTM 109
Query: 78 IRYLL--EQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVDPKKPFRKLSRFGNAF 135
I YLL E + G EPTT F +M+G + G + D + F L +FG F
Sbjct: 110 INYLLGLENTRYQLYTGAEPTTSEFTVLMHGPKLKTIEGIVMAADSARSFSPLEKFGQNF 169
Query: 136 LNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAH 195
L + + ++P+++L+ ++ +D+PGI+ KQ+ RGY F V QWF +R D I ++FD
Sbjct: 170 LEKLIGIEVPHKLLERVTFVDTPGIIENRKQQ-ERGYPFNDVCQWFIDRADLIFVVFDPT 228
Query: 196 KLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRV 255
KLD+ E + +G++ +IR++LNKAD + TQ LMRVYGAL WSL +IN E RV
Sbjct: 229 KLDVGLELEMLFRQLKGRESQIRIILNKADNLATQMLMRVYGALFWSLAPLINVTEPPRV 288
Query: 256 YIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIIS 315
Y+ SFW Q + ++ LF E L D+ + + K+ + + A ++HA ++
Sbjct: 289 YVSSFWPQEYKPDTHQELFLQEEISLLEDLNQVIENRLENKIAFIRQHAIRVRIHALLVD 348
Query: 316 -YL---KKEMPSVFGKENKKRELISRLPEIYI--QLQREYQISAGDFPEVKAMQE 364
YL K +M E ++++ + YI + + +S D P +A ++
Sbjct: 349 RYLQTYKDKMTFFSDGELVFKDIVEDPDKFYIFKTILAKTNVSKFDLPNREAYKD 403
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 99.8 bits (247), Expect = 6e-21
Identities = 50/101 (49%), Positives = 68/101 (67%), Gaps = 1/101 (0%)
Query: 437 ADEEEWVVA-KDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDC 495
A E W V +DK YD +F +LSP+NG +SG K ++ SKLP +LG++W+L+D D
Sbjct: 117 AAELPWAVKPEDKAKYDAIFDSLSPVNGFLSGDKVKPVLLNSKLPVDILGRVWELSDIDH 176
Query: 496 DGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRKS 536
DGMLD +EFA+A L+ L+ +P SLPP LVPPS RK+
Sbjct: 177 DGMLDRDEFAVAMFLVYCALEKEPVPMSLPPALVPPSKRKT 217
Score = 70.1 bits (170), Expect = 5e-12
Identities = 41/101 (40%), Positives = 61/101 (60%), Gaps = 3/101 (2%)
Query: 442 WVVAK-DKPVYDELFY-TLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGML 499
WVV+ +K YDE+F T ++G +SG+ ++ + + LP+++L IW L D G L
Sbjct: 218 WVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIWSLCDTKDCGKL 277
Query: 500 DEEEFALAKHLIKIKL-DGYELPSSLPPHLVPPSHRKSLPK 539
+++FALA HLI KL G + P L P ++PPS R SL K
Sbjct: 278 SKDQFALAFHLISQKLIKGIDPPHVLTPEMIPPSDRASLQK 318
Score = 52.8 bits (125), Expect = 8e-07
Identities = 30/89 (33%), Positives = 50/89 (56%), Gaps = 1/89 (1%)
Query: 444 VAKDKPVYDELFYTLSPIN-GKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEE 502
++ PVY++ + + N G++ +A + S LP+ +LGKIW LAD D G+L+++
Sbjct: 12 LSSGNPVYEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQ 71
Query: 503 EFALAKHLIKIKLDGYELPSSLPPHLVPP 531
EF +A L+ +G E+ S VPP
Sbjct: 72 EFFVALRLVACAQNGLEVSLSSLNLAVPP 100
>gi|10864047 epidermal growth factor receptor pathway substrate
15-like 1 [Homo sapiens]
Length = 864
Score = 95.9 bits (237), Expect = 8e-20
Identities = 47/98 (47%), Positives = 65/98 (66%), Gaps = 1/98 (1%)
Query: 439 EEEWVV-AKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDG 497
E W V ++K +D +F +L PING +SG K ++ SKLP VLG++W L+D D DG
Sbjct: 118 EAHWAVRVEEKAKFDGIFESLLPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDG 177
Query: 498 MLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRK 535
LD +EFA+A HL+ L+ +PS+LPP L+PPS RK
Sbjct: 178 HLDRDEFAVAMHLVYRALEKEPVPSALPPSLIPPSKRK 215
Score = 60.8 bits (146), Expect = 3e-09
Identities = 38/96 (39%), Positives = 55/96 (57%), Gaps = 3/96 (3%)
Query: 442 WVV-AKDKPVYDELFY-TLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGML 499
WVV DK +DE+F T ++G +SG K+ + S L ++L IW LAD G L
Sbjct: 269 WVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKL 328
Query: 500 DEEEFALAKHLIKIKLD-GYELPSSLPPHLVPPSHR 534
+++FALA + I+ K+ G + P L P +VPPS R
Sbjct: 329 SKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSER 364
Score = 43.9 bits (102), Expect = 4e-04
Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 9/95 (9%)
Query: 450 VYDELFYTLSPI-NGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAK 508
+Y+ + + P G++ A + S L + +LGKIW LAD + G LD++ F +A
Sbjct: 18 LYESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVAL 77
Query: 509 HLIKIKLDGYE-----LPSSLPPHLVPPSHRKSLP 538
L+ G+E L S+PP P H S P
Sbjct: 78 RLVACAQSGHEVTLSNLNLSMPP---PKFHDTSSP 109
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 83.6 bits (205), Expect = 4e-16
Identities = 40/92 (43%), Positives = 61/92 (66%), Gaps = 1/92 (1%)
Query: 436 GADEEEWVVA-KDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCD 494
G + W + +++ +D+ F++L PI+G I+G A+ S LP VL +IW LAD +
Sbjct: 9 GGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMN 68
Query: 495 CDGMLDEEEFALAKHLIKIKLDGYELPSSLPP 526
DG +D+ EF++A LIK+KL GY+LPS+LPP
Sbjct: 69 NDGRMDQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 74.3 bits (181), Expect = 3e-13
Identities = 39/97 (40%), Positives = 56/97 (57%), Gaps = 2/97 (2%)
Query: 441 EWVVAKDKPV-YDELFYTLSP-INGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGM 498
EW V + + Y +LF + ++G ++G A+ ++ S LP + L IW L+D D DG
Sbjct: 214 EWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGK 273
Query: 499 LDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRK 535
L EEF LA HLI + + G LP LPP +PPS R+
Sbjct: 274 LTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRR 310
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 83.6 bits (205), Expect = 4e-16
Identities = 40/92 (43%), Positives = 61/92 (66%), Gaps = 1/92 (1%)
Query: 436 GADEEEWVVA-KDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCD 494
G + W + +++ +D+ F++L PI+G I+G A+ S LP VL +IW LAD +
Sbjct: 9 GGSLDIWAITVEERAKHDQQFHSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMN 68
Query: 495 CDGMLDEEEFALAKHLIKIKLDGYELPSSLPP 526
DG +D+ EF++A LIK+KL GY+LPS+LPP
Sbjct: 69 NDGRMDQVEFSIAMKLIKLKLQGYQLPSALPP 100
Score = 74.3 bits (181), Expect = 3e-13
Identities = 39/97 (40%), Positives = 56/97 (57%), Gaps = 2/97 (2%)
Query: 441 EWVVAKDKPV-YDELFYTLSP-INGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGM 498
EW V + + Y +LF + ++G ++G A+ ++ S LP + L IW L+D D DG
Sbjct: 214 EWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGK 273
Query: 499 LDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRK 535
L EEF LA HLI + + G LP LPP +PPS R+
Sbjct: 274 LTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRR 310
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 73.6 bits (179), Expect = 4e-13
Identities = 45/107 (42%), Positives = 57/107 (53%), Gaps = 4/107 (3%)
Query: 430 GEGAKEGADEEEWVVAKDKPV-YDELFYTLSP-INGKISGVNAKKEMVTSKLPNSVLGKI 487
G K G E W V + + Y + F TL ++G +SG A+ ++ S L + L I
Sbjct: 228 GNSPKTGTSE--WAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATI 285
Query: 488 WKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHR 534
W LAD D DG L EEF LA HL + G LP +LPP LVPPS R
Sbjct: 286 WTLADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVPPSFR 332
Score = 73.2 bits (178), Expect = 6e-13
Identities = 35/89 (39%), Positives = 55/89 (61%)
Query: 443 VVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEE 502
+ ++++ +D F L P G I+G A+ + S LP VL +IW L+D + DG +D++
Sbjct: 18 ITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQ 77
Query: 503 EFALAKHLIKIKLDGYELPSSLPPHLVPP 531
EF++A LIK+KL G +LP LPP + P
Sbjct: 78 EFSIAMKLIKLKLQGQQLPVVLPPIMKQP 106
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 73.6 bits (179), Expect = 4e-13
Identities = 45/107 (42%), Positives = 57/107 (53%), Gaps = 4/107 (3%)
Query: 430 GEGAKEGADEEEWVVAKDKPV-YDELFYTLSP-INGKISGVNAKKEMVTSKLPNSVLGKI 487
G K G E W V + + Y + F TL ++G +SG A+ ++ S L + L I
Sbjct: 228 GNSPKTGTSE--WAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATI 285
Query: 488 WKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHR 534
W LAD D DG L EEF LA HL + G LP +LPP LVPPS R
Sbjct: 286 WTLADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVPPSFR 332
Score = 73.2 bits (178), Expect = 6e-13
Identities = 35/89 (39%), Positives = 55/89 (61%)
Query: 443 VVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEE 502
+ ++++ +D F L P G I+G A+ + S LP VL +IW L+D + DG +D++
Sbjct: 18 ITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQ 77
Query: 503 EFALAKHLIKIKLDGYELPSSLPPHLVPP 531
EF++A LIK+KL G +LP LPP + P
Sbjct: 78 EFSIAMKLIKLKLQGQQLPVVLPPIMKQP 106
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 73.6 bits (179), Expect = 4e-13
Identities = 45/107 (42%), Positives = 57/107 (53%), Gaps = 4/107 (3%)
Query: 430 GEGAKEGADEEEWVVAKDKPV-YDELFYTLSP-INGKISGVNAKKEMVTSKLPNSVLGKI 487
G K G E W V + + Y + F TL ++G +SG A+ ++ S L + L I
Sbjct: 228 GNSPKTGTSE--WAVPQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATI 285
Query: 488 WKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHR 534
W LAD D DG L EEF LA HL + G LP +LPP LVPPS R
Sbjct: 286 WTLADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVPPSFR 332
Score = 73.2 bits (178), Expect = 6e-13
Identities = 35/89 (39%), Positives = 55/89 (61%)
Query: 443 VVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEE 502
+ ++++ +D F L P G I+G A+ + S LP VL +IW L+D + DG +D++
Sbjct: 18 ITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLAEIWALSDLNKDGKMDQQ 77
Query: 503 EFALAKHLIKIKLDGYELPSSLPPHLVPP 531
EF++A LIK+KL G +LP LPP + P
Sbjct: 78 EFSIAMKLIKLKLQGQQLPVVLPPIMKQP 106
>gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2
[Homo sapiens]
Length = 659
Score = 67.4 bits (163), Expect = 3e-11
Identities = 41/103 (39%), Positives = 53/103 (51%), Gaps = 2/103 (1%)
Query: 439 EEEWVVAKD-KPVYDELFYTLSPINGK-ISGVNAKKEMVTSKLPNSVLGKIWKLADCDCD 496
+E W + ++ + Y F +L P ISG AK SKL L IW+L+D DCD
Sbjct: 272 DEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCD 331
Query: 497 GMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRKSLPK 539
G L EF A HLI + +GY LP LPP L P + + PK
Sbjct: 332 GALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQPEYLQAAFPK 374
>gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1
[Homo sapiens]
Length = 660
Score = 67.4 bits (163), Expect = 3e-11
Identities = 41/103 (39%), Positives = 53/103 (51%), Gaps = 2/103 (1%)
Query: 439 EEEWVVAKD-KPVYDELFYTLSPINGK-ISGVNAKKEMVTSKLPNSVLGKIWKLADCDCD 496
+E W + ++ + Y F +L P ISG AK SKL L IW+L+D DCD
Sbjct: 273 DEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCD 332
Query: 497 GMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRKSLPK 539
G L EF A HLI + +GY LP LPP L P + + PK
Sbjct: 333 GALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQPEYLQAAFPK 375
>gi|190886435 RALBP1 associated Eps domain containing 1 isoform a
[Homo sapiens]
Length = 795
Score = 67.0 bits (162), Expect = 4e-11
Identities = 37/94 (39%), Positives = 53/94 (56%), Gaps = 2/94 (2%)
Query: 439 EEEWVVAKD-KPVYDELFYTLSP-INGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCD 496
++ W + + + Y F T+ P +NG I G AK+ SKLP L IW+L+D D D
Sbjct: 276 DDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKD 335
Query: 497 GMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVP 530
G L +EF A HL+ + +GY+LP LP L+P
Sbjct: 336 GALTLDEFCAAFHLVVARKNGYDLPEKLPESLMP 369
>gi|190886437 RALBP1 associated Eps domain containing 1 isoform b
[Homo sapiens]
Length = 769
Score = 67.0 bits (162), Expect = 4e-11
Identities = 37/94 (39%), Positives = 53/94 (56%), Gaps = 2/94 (2%)
Query: 439 EEEWVVAKD-KPVYDELFYTLSP-INGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCD 496
++ W + + + Y F T+ P +NG I G AK+ SKLP L IW+L+D D D
Sbjct: 276 DDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKD 335
Query: 497 GMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVP 530
G L +EF A HL+ + +GY+LP LP L+P
Sbjct: 336 GALTLDEFCAAFHLVVARKNGYDLPEKLPESLMP 369
>gi|105990532 apolipoprotein B precursor [Homo sapiens]
Length = 4563
Score = 36.2 bits (82), Expect = 0.078
Identities = 34/138 (24%), Positives = 64/138 (46%), Gaps = 26/138 (18%)
Query: 277 EAQDLFRDIQSLPQKAAVRKLNDL-----------IKRARLAKVHAYIISYLKKEMPSVF 325
EAQ++F+ IQSL +R L DL IK+ + K Y+I+Y++ E+ ++F
Sbjct: 4279 EAQEVFKAIQSLKTTEVLRNLQDLLQFIFQLIEDNIKQLKEMK-FTYLINYIQDEINTIF 4337
Query: 326 GK------ENKKRELISRLPEIYIQLQREYQISAGDFPEVK--AMQEQLENYD------F 371
+ K L L + +Q E Q ++ + ++ M + E +D
Sbjct: 4338 SDYIPYVFKLLKENLCLNLHKFNEFIQNELQEASQELQQIHQYIMALREEYFDPSIVGWT 4397
Query: 372 TKFHSLKPKLIEAVDNML 389
K++ L+ K++ + N+L
Sbjct: 4398 VKYYELEEKIVSLIKNLL 4415
>gi|52856430 protein expressed in prostate, ovary, testis, and
placenta 15 [Homo sapiens]
Length = 581
Score = 32.7 bits (73), Expect = 0.87
Identities = 28/117 (23%), Positives = 51/117 (43%), Gaps = 3/117 (2%)
Query: 269 DNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPSVFGKE 328
+N++ + E ++ D Q+ QK + N I + + I +KEM S
Sbjct: 456 ENQQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEMNSKLSLS 515
Query: 329 NKKRELISRLPEIYIQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAV 385
+KK E + R + L+ E + + E K + EN + S+K KL++A+
Sbjct: 516 HKKEEDLLRENSM---LREEIAMLRLELDETKHQNQLRENKILEEIESVKEKLLKAI 569
>gi|40217805 nucleolar protein 9 [Homo sapiens]
Length = 702
Score = 32.7 bits (73), Expect = 0.87
Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 10/100 (10%)
Query: 27 GLRSLYLRKVLPLEEAY--RFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQ 84
G+R RK L L E+ E + + E+ D P+IL+ G GK+TF RYL+
Sbjct: 265 GIRREKKRKGLQLTESTLSALEELVNVSCEEVD--GCPVILVCGSQDVGKSTFNRYLINH 322
Query: 85 DFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVDPKKP 124
+ P D ++ G+TE + PG +++ +P
Sbjct: 323 -----LLNSLPCVD-YLECDLGQTEFTPPGCISLLNITEP 356
>gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Homo
sapiens]
Length = 1134
Score = 31.2 bits (69), Expect = 2.5
Identities = 36/146 (24%), Positives = 65/146 (44%), Gaps = 11/146 (7%)
Query: 263 QPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKR--ARLAKVHAYIISYLKKE 320
Q L T +RL + QD R Q + ++ +++L ++ + A+L KV A LK
Sbjct: 152 QQLLATKEQRLKFLKQQDQ-RQQQQVAEQEKLKRLKEIAENQEAKLKKVRA-----LKGH 205
Query: 321 MPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPK 380
+ K E I ++ ++ Q QRE ++ E+ E L+N H +
Sbjct: 206 VEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEMLKNGRIDSHHDNQSA 265
Query: 381 LIEAVDNMLSNKISPLMNLISQEETS 406
+ E +D + K L N ++QE+ +
Sbjct: 266 VAE-LDRLY--KELQLRNKLNQEQNA 288
>gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo
sapiens]
Length = 1005
Score = 31.2 bits (69), Expect = 2.5
Identities = 36/146 (24%), Positives = 65/146 (44%), Gaps = 11/146 (7%)
Query: 263 QPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKR--ARLAKVHAYIISYLKKE 320
Q L T +RL + QD R Q + ++ +++L ++ + A+L KV A LK
Sbjct: 23 QQLLATKEQRLKFLKQQDQ-RQQQQVAEQEKLKRLKEIAENQEAKLKKVRA-----LKGH 76
Query: 321 MPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPK 380
+ K E I ++ ++ Q QRE ++ E+ E L+N H +
Sbjct: 77 VEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEMLKNGRIDSHHDNQSA 136
Query: 381 LIEAVDNMLSNKISPLMNLISQEETS 406
+ E +D + K L N ++QE+ +
Sbjct: 137 VAE-LDRLY--KELQLRNKLNQEQNA 159
>gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo
sapiens]
Length = 817
Score = 31.2 bits (69), Expect = 2.5
Identities = 31/137 (22%), Positives = 63/137 (45%), Gaps = 10/137 (7%)
Query: 275 EAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPSVFGKENKKREL 334
EAE Q L R +QSL Q+ K +++A+L + + K+ M + G + + L
Sbjct: 682 EAEIQQLKRKLQSLEQE----KGRWRVEKAQLEQ----SVEENKERMEKLEGYWGEAQSL 733
Query: 335 ISRLPEIYIQLQREYQISAGDFPEVKAM--QEQLENYDFTKFHSLKPKLIEAVDNMLSNK 392
+ E + Q +YQ + + K + Q + +F K + + +++E + +
Sbjct: 734 CQAVDEHLRETQAQYQALERKYSKAKRLIKDYQQKEIEFLKKETAQRRVLEESELARKEE 793
Query: 393 ISPLMNLISQEETSTPT 409
+ L++ IS+ E + T
Sbjct: 794 MDKLLDKISELEGNLQT 810
>gi|38569411 AP1 gamma subunit binding protein 1 isoform 2 [Homo
sapiens]
Length = 1302
Score = 30.4 bits (67), Expect = 4.3
Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 474 MVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHL 528
+++S LP LG+IW LA+ G L +EE +I + G +P+ P L
Sbjct: 325 LMSSGLPRETLGQIWALANRTTPGKLTKEELYTVLAMIAVTQRG--VPAMSPDAL 377
>gi|38569409 AP1 gamma subunit binding protein 1 isoform 1 [Homo
sapiens]
Length = 1314
Score = 30.4 bits (67), Expect = 4.3
Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 474 MVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHL 528
+++S LP LG+IW LA+ G L +EE +I + G +P+ P L
Sbjct: 325 LMSSGLPRETLGQIWALANRTTPGKLTKEELYTVLAMIAVTQRG--VPAMSPDAL 377
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 30.4 bits (67), Expect = 4.3
Identities = 29/126 (23%), Positives = 59/126 (46%), Gaps = 14/126 (11%)
Query: 328 ENKKRELISRLPEIYIQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEA--- 384
E K ++ ++ +Q+ + + S DF EV ++++LE+ D + L + +A
Sbjct: 2109 EVPKEKMADEQGDMDLQISPDRKTST-DFSEV--IKQELEDNDKYQQFRLSEETEKAQLH 2165
Query: 385 VDNMLSNKISPLMNLISQEETSTPTQLVQGGAFDGTTEGPFNQGYG--------EGAKEG 436
+D +L++ + L ++ P +Q GA DG++E N+G EG +
Sbjct: 2166 LDQVLTSPFNTTFPLDYMKDEFLPALSLQSGALDGSSESLKNEGVAGSPCGSLMEGTPQI 2225
Query: 437 ADEEEW 442
+ EE +
Sbjct: 2226 SSEESY 2231
>gi|15487670 nuclear RNA export factor 1 isoform 1 [Homo sapiens]
Length = 619
Score = 30.0 bits (66), Expect = 5.6
Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 8/75 (10%)
Query: 465 ISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEF--ALAKHLIK-IKLDGYELP 521
+SG K E K+ L ++W + CD D+ + A+ + K ++LDG+ELP
Sbjct: 298 LSGNELKSERELDKIKGLKLEELWLDGNSLCDTFRDQSTYISAIRERFPKLLRLDGHELP 357
Query: 522 SSL-----PPHLVPP 531
+ P +PP
Sbjct: 358 PPIAFDVEAPTTLPP 372
>gi|5803029 ATP/GTP-binding protein isoform 1 [Homo sapiens]
Length = 425
Score = 30.0 bits (66), Expect = 5.6
Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 14/84 (16%)
Query: 31 LYLRKVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMR 90
LYL LE+ R E + E P +++VG GK+T R LL +R
Sbjct: 92 LYLNTHTALEQMRRQAE--------KEEERGPRVMVVGPTDVGKSTVCRLLLNY---AVR 140
Query: 91 IGPEPTTDSFIAVMYGETEGSTPG 114
+G PT ++ + G+ S PG
Sbjct: 141 LGRRPT---YVELDVGQGSVSIPG 161
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 29.6 bits (65), Expect = 7.3
Identities = 67/357 (18%), Positives = 133/357 (37%), Gaps = 57/357 (15%)
Query: 186 DRIILLFDAHKLDISDEFSE------AIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGAL 239
D+I LL + + +IS++ E KA + + K++ ++++ D + M +
Sbjct: 680 DKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEK--CI 737
Query: 240 MWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLND 299
K+ E+L + Q + E L +++Q L K ND
Sbjct: 738 QEKDEKLKTVEELLETGL----IQVATKEEELNAIRTENSSLTKEVQDLKAKQ-----ND 788
Query: 300 LIKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFP-E 358
+ A L + E+ V +++ K + + L E + + + D E
Sbjct: 789 QVSFASLVE-----------ELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQE 837
Query: 359 VKAMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLIS--QEETSTPTQLVQGGA 416
+KA++E++ N K L +++K+ L NL+ +E+ +T +++
Sbjct: 838 IKALKEEIGNVQLEKAQQLS----------ITSKVQELQNLLKGKEEQMNTMKAVLEEKE 887
Query: 417 FDGTTEGPFNQGYGEGAKEGADEEEWVV------AKDKPVYDELFYTLSPINGKISGVNA 470
D G + Q E + + V A ++EL L ++ + A
Sbjct: 888 KDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEA 947
Query: 471 KKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPH 527
+ S L + K L D + +E + ++K Y+ SS PPH
Sbjct: 948 MLKERESDLSS----KTQLLQD------VQDENKLFKSQIEQLKQQNYQQASSFPPH 994
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 29.6 bits (65), Expect = 7.3
Identities = 67/357 (18%), Positives = 133/357 (37%), Gaps = 57/357 (15%)
Query: 186 DRIILLFDAHKLDISDEFSE------AIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGAL 239
D+I LL + + +IS++ E KA + + K++ ++++ D + M +
Sbjct: 680 DKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEK--CI 737
Query: 240 MWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLND 299
K+ E+L + Q + E L +++Q L K ND
Sbjct: 738 QEKDEKLKTVEELLETGL----IQVATKEEELNAIRTENSSLTKEVQDLKAKQ-----ND 788
Query: 300 LIKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFP-E 358
+ A L + E+ V +++ K + + L E + + + D E
Sbjct: 789 QVSFASLVE-----------ELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQE 837
Query: 359 VKAMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLIS--QEETSTPTQLVQGGA 416
+KA++E++ N K L +++K+ L NL+ +E+ +T +++
Sbjct: 838 IKALKEEIGNVQLEKAQQLS----------ITSKVQELQNLLKGKEEQMNTMKAVLEEKE 887
Query: 417 FDGTTEGPFNQGYGEGAKEGADEEEWVV------AKDKPVYDELFYTLSPINGKISGVNA 470
D G + Q E + + V A ++EL L ++ + A
Sbjct: 888 KDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEA 947
Query: 471 KKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPH 527
+ S L + K L D + +E + ++K Y+ SS PPH
Sbjct: 948 MLKERESDLSS----KTQLLQD------VQDENKLFKSQIEQLKQQNYQQASSFPPH 994
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 29.6 bits (65), Expect = 7.3
Identities = 67/357 (18%), Positives = 133/357 (37%), Gaps = 57/357 (15%)
Query: 186 DRIILLFDAHKLDISDEFSE------AIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGAL 239
D+I LL + + +IS++ E KA + + K++ ++++ D + M +
Sbjct: 680 DKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEK--CI 737
Query: 240 MWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLND 299
K+ E+L + Q + E L +++Q L K ND
Sbjct: 738 QEKDEKLKTVEELLETGL----IQVATKEEELNAIRTENSSLTKEVQDLKAKQ-----ND 788
Query: 300 LIKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFP-E 358
+ A L + E+ V +++ K + + L E + + + D E
Sbjct: 789 QVSFASLVE-----------ELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQE 837
Query: 359 VKAMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLIS--QEETSTPTQLVQGGA 416
+KA++E++ N K L +++K+ L NL+ +E+ +T +++
Sbjct: 838 IKALKEEIGNVQLEKAQQLS----------ITSKVQELQNLLKGKEEQMNTMKAVLEEKE 887
Query: 417 FDGTTEGPFNQGYGEGAKEGADEEEWVV------AKDKPVYDELFYTLSPINGKISGVNA 470
D G + Q E + + V A ++EL L ++ + A
Sbjct: 888 KDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEA 947
Query: 471 KKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPH 527
+ S L + K L D + +E + ++K Y+ SS PPH
Sbjct: 948 MLKERESDLSS----KTQLLQD------VQDENKLFKSQIEQLKQQNYQQASSFPPH 994
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,090,041
Number of Sequences: 37866
Number of extensions: 967104
Number of successful extensions: 2411
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 2367
Number of HSP's gapped (non-prelim): 57
length of query: 541
length of database: 18,247,518
effective HSP length: 107
effective length of query: 434
effective length of database: 14,195,856
effective search space: 6161001504
effective search space used: 6161001504
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.