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Search of human proteins with 209977023
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|209977023 secretory protein LOC348174 [Homo sapiens]
(446 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|227497624 secretory protein LOC348174 [Homo sapiens] 959 0.0
gi|209977023 secretory protein LOC348174 [Homo sapiens] 959 0.0
gi|58866695 mannose receptor-like [Homo sapiens] 954 0.0
gi|194018451 C-type lectin domain family 18, member B [Homo sapi... 942 0.0
gi|70780384 protease inhibitor 16 precursor [Homo sapiens] 97 3e-20
gi|13899332 cysteine-rich secretory protein LCCL domain containi... 94 3e-19
gi|7705676 protease inhibitor 15 preproprotein [Homo sapiens] 93 4e-19
gi|22749527 GLI pathogenesis-related 1 like 1 [Homo sapiens] 92 7e-19
gi|30425410 R3H domain containing-like [Homo sapiens] 91 2e-18
gi|5174675 cysteine-rich secretory protein 3 [Homo sapiens] 91 3e-18
gi|13899303 cysteine-rich secretory protein LCCL domain containi... 87 4e-17
gi|215422434 cysteine-rich secretory protein 2 [Homo sapiens] 84 3e-16
gi|215422430 cysteine-rich secretory protein 2 [Homo sapiens] 84 3e-16
gi|4507671 cysteine-rich secretory protein 2 [Homo sapiens] 84 3e-16
gi|215490058 cysteine-rich secretory protein 2 [Homo sapiens] 84 3e-16
gi|215490018 cysteine-rich secretory protein 2 [Homo sapiens] 84 3e-16
gi|110825980 GLI pathogenesis-related 1 precursor [Homo sapiens] 83 6e-16
gi|25121982 acidic epididymal glycoprotein-like 1 isoform 1 prec... 80 5e-15
gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens] 71 2e-12
gi|25121984 acidic epididymal glycoprotein-like 1 isoform 2 prec... 70 4e-12
gi|4505245 mannose receptor C type 1 precursor [Homo sapiens] 69 7e-12
gi|57546917 mannose receptor, C type 1-like 1 [Homo sapiens] 69 7e-12
gi|187607300 versican isoform 2 [Homo sapiens] 67 3e-11
gi|21361116 versican isoform 1 [Homo sapiens] 66 6e-11
gi|22748923 GLI pathogenesis-related 1 like 2 [Homo sapiens] 66 7e-11
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 63 6e-10
gi|116235485 delta-notch-like EGF repeat-containing transmembran... 59 7e-09
gi|148833508 notch1 preproprotein [Homo sapiens] 59 1e-08
gi|126090892 aggrecan isoform 2 precursor [Homo sapiens] 58 2e-08
gi|156627579 C-type lectin domain family 3, member B [Homo sapiens] 58 2e-08
>gi|227497624 secretory protein LOC348174 [Homo sapiens]
Length = 446
Score = 959 bits (2480), Expect = 0.0
Identities = 446/446 (100%), Positives = 446/446 (100%)
Query: 1 MLHPETSPGRGHLLAVLLALLGTAWAEVWPPQLQEQAPMAGALNRKESFLLLSLHNRLRS 60
MLHPETSPGRGHLLAVLLALLGTAWAEVWPPQLQEQAPMAGALNRKESFLLLSLHNRLRS
Sbjct: 1 MLHPETSPGRGHLLAVLLALLGTAWAEVWPPQLQEQAPMAGALNRKESFLLLSLHNRLRS 60
Query: 61 WVQPPAADMRRLDWSDSLAQLAQARAALCGTPTPSLASGLWRTLQVGWNMQLLPAGLVSF 120
WVQPPAADMRRLDWSDSLAQLAQARAALCGTPTPSLASGLWRTLQVGWNMQLLPAGLVSF
Sbjct: 61 WVQPPAADMRRLDWSDSLAQLAQARAALCGTPTPSLASGLWRTLQVGWNMQLLPAGLVSF 120
Query: 121 VEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQAAIEAFVC 180
VEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQAAIEAFVC
Sbjct: 121 VEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQAAIEAFVC 180
Query: 181 AYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHG 240
AYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHG
Sbjct: 181 AYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHG 240
Query: 241 RLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFH 300
RLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFH
Sbjct: 241 RLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFH 300
Query: 301 TCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVI 360
TCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVI
Sbjct: 301 TCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVI 360
Query: 361 DSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNHGFGNCVELQASAAFNWN 420
DSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNHGFGNCVELQASAAFNWN
Sbjct: 361 DSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNHGFGNCVELQASAAFNWN 420
Query: 421 DQRCKTRNRYICQFAQEHISRWGPGS 446
DQRCKTRNRYICQFAQEHISRWGPGS
Sbjct: 421 DQRCKTRNRYICQFAQEHISRWGPGS 446
>gi|209977023 secretory protein LOC348174 [Homo sapiens]
Length = 446
Score = 959 bits (2480), Expect = 0.0
Identities = 446/446 (100%), Positives = 446/446 (100%)
Query: 1 MLHPETSPGRGHLLAVLLALLGTAWAEVWPPQLQEQAPMAGALNRKESFLLLSLHNRLRS 60
MLHPETSPGRGHLLAVLLALLGTAWAEVWPPQLQEQAPMAGALNRKESFLLLSLHNRLRS
Sbjct: 1 MLHPETSPGRGHLLAVLLALLGTAWAEVWPPQLQEQAPMAGALNRKESFLLLSLHNRLRS 60
Query: 61 WVQPPAADMRRLDWSDSLAQLAQARAALCGTPTPSLASGLWRTLQVGWNMQLLPAGLVSF 120
WVQPPAADMRRLDWSDSLAQLAQARAALCGTPTPSLASGLWRTLQVGWNMQLLPAGLVSF
Sbjct: 61 WVQPPAADMRRLDWSDSLAQLAQARAALCGTPTPSLASGLWRTLQVGWNMQLLPAGLVSF 120
Query: 121 VEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQAAIEAFVC 180
VEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQAAIEAFVC
Sbjct: 121 VEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQAAIEAFVC 180
Query: 181 AYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHG 240
AYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHG
Sbjct: 181 AYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHG 240
Query: 241 RLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFH 300
RLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFH
Sbjct: 241 RLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFH 300
Query: 301 TCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVI 360
TCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVI
Sbjct: 301 TCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVI 360
Query: 361 DSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNHGFGNCVELQASAAFNWN 420
DSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNHGFGNCVELQASAAFNWN
Sbjct: 361 DSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNHGFGNCVELQASAAFNWN 420
Query: 421 DQRCKTRNRYICQFAQEHISRWGPGS 446
DQRCKTRNRYICQFAQEHISRWGPGS
Sbjct: 421 DQRCKTRNRYICQFAQEHISRWGPGS 446
>gi|58866695 mannose receptor-like [Homo sapiens]
Length = 446
Score = 954 bits (2465), Expect = 0.0
Identities = 443/446 (99%), Positives = 444/446 (99%)
Query: 1 MLHPETSPGRGHLLAVLLALLGTAWAEVWPPQLQEQAPMAGALNRKESFLLLSLHNRLRS 60
MLHPETSPGRGHLLAVLLALLGTAWAEVWPPQLQEQAPMAGALNRKESFLLLSLHNRLRS
Sbjct: 1 MLHPETSPGRGHLLAVLLALLGTAWAEVWPPQLQEQAPMAGALNRKESFLLLSLHNRLRS 60
Query: 61 WVQPPAADMRRLDWSDSLAQLAQARAALCGTPTPSLASGLWRTLQVGWNMQLLPAGLVSF 120
WVQPPAADMRRLDWSDSLAQLAQARAALCG PTPSLASGLWRTLQVGWNMQLLPAGL SF
Sbjct: 61 WVQPPAADMRRLDWSDSLAQLAQARAALCGIPTPSLASGLWRTLQVGWNMQLLPAGLASF 120
Query: 121 VEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQAAIEAFVC 180
VEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQAAIEAFVC
Sbjct: 121 VEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQAAIEAFVC 180
Query: 181 AYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHG 240
AYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHG
Sbjct: 181 AYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHG 240
Query: 241 RLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFH 300
RLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFH
Sbjct: 241 RLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFH 300
Query: 301 TCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVI 360
TCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVI
Sbjct: 301 TCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVI 360
Query: 361 DSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNHGFGNCVELQASAAFNWN 420
DSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNHGFGNCVELQASAAFNWN
Sbjct: 361 DSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNHGFGNCVELQASAAFNWN 420
Query: 421 DQRCKTRNRYICQFAQEHISRWGPGS 446
+QRCKTRNRYICQFAQEHISRWGPGS
Sbjct: 421 NQRCKTRNRYICQFAQEHISRWGPGS 446
>gi|194018451 C-type lectin domain family 18, member B [Homo
sapiens]
Length = 455
Score = 942 bits (2434), Expect = 0.0
Identities = 440/455 (96%), Positives = 441/455 (96%), Gaps = 9/455 (1%)
Query: 1 MLHPETSPGRGHLLAVLLALLGTAWAEVWPPQLQEQAPMAGALNRKESFLLLSLHNRLRS 60
MLHPETSPGRGHLLAVLLALLGT WAEVWPPQLQEQAPMAGALNRKESFLLLSLHNRLRS
Sbjct: 1 MLHPETSPGRGHLLAVLLALLGTTWAEVWPPQLQEQAPMAGALNRKESFLLLSLHNRLRS 60
Query: 61 WVQPPAADMRRLDWSDSLAQLAQARAALCGTPTPSLASGLWRTLQVGWNMQLLPAGLVSF 120
WVQPPAADMRRLDWSDSLAQLAQARAALCG PTPSLASGLWRTLQVGWNMQLLPAGL SF
Sbjct: 61 WVQPPAADMRRLDWSDSLAQLAQARAALCGIPTPSLASGLWRTLQVGWNMQLLPAGLASF 120
Query: 121 VEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQAAIEAFVC 180
VEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQ AIEAFVC
Sbjct: 121 VEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQTAIEAFVC 180
Query: 181 AYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHG 240
AYSP GNWEVNGKTI+PYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHG
Sbjct: 181 AYSPGGNWEVNGKTIIPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHG 240
Query: 241 RLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFH 300
RLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFH
Sbjct: 241 RLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFH 300
Query: 301 TCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVI 360
TCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVI
Sbjct: 301 TCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVI 360
Query: 361 DSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNH---------GFGNCVEL 411
DSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNH GFGNCVEL
Sbjct: 361 DSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNHGLVWLSAAMGFGNCVEL 420
Query: 412 QASAAFNWNDQRCKTRNRYICQFAQEHISRWGPGS 446
QASAAFNWNDQRCKTRNRYICQFAQEHISRWGPGS
Sbjct: 421 QASAAFNWNDQRCKTRNRYICQFAQEHISRWGPGS 455
>gi|70780384 protease inhibitor 16 precursor [Homo sapiens]
Length = 463
Score = 97.1 bits (240), Expect = 3e-20
Identities = 60/175 (34%), Positives = 82/175 (46%), Gaps = 22/175 (12%)
Query: 41 GALNRKESFLLLSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALC----GTPTPSL 96
GAL +E L++ LHN R+ V P A+DM + W + LA A+A A C
Sbjct: 26 GALTDEEKRLMVELHNLYRAQVSPTASDMLHMRWDEELAAFAKAYARQCVWGHNKERGRR 85
Query: 97 ASGLWRTLQVGWNMQLLPAGLVSFVEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWA 156
L+ G ++ L + W E + Y+ +A C+ C HYTQ+VWA
Sbjct: 86 GENLFAITDEGMDVPL----------AMEEWHHEREHYNLSAATCSPGQMCGHYTQVVWA 135
Query: 157 TSSQLGCGRHLCSAGQAA----IEAFVCAYSPRGNWEVNGKTIVPYKKGAWCSLC 207
+ ++GCG H C Q IE VC Y P GN V GK PY++G CS C
Sbjct: 136 KTERIGCGSHFCEKLQGVEETNIELLVCNYEPPGN--VKGKR--PYQEGTPCSQC 186
>gi|13899332 cysteine-rich secretory protein LCCL domain containing
2 [Homo sapiens]
Length = 497
Score = 93.6 bits (231), Expect = 3e-19
Identities = 66/189 (34%), Positives = 90/189 (47%), Gaps = 28/189 (14%)
Query: 42 ALNRKESFLLLSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALC---GTPTPSLAS 98
A+ R++ +L LHN+LR VQP A++M + W D L + A A A+ C PT SL
Sbjct: 50 AIPREDKEEILMLHNKLRGQVQPQASNMEYMTWDDELEKSAAAWASQCIWEHGPT-SLLV 108
Query: 99 GLWRTLQVGWNMQLLPAGLVSFVEVVSLWFAEGQRYSHA-AGEC-------ARNATCTHY 150
+ + L W P V W+ E + Y++ EC CTHY
Sbjct: 109 SIGQNLGAHWGRYRSPG------FHVQSWYDEVKDYTYPYPSECNPWCPERCSGPMCTHY 162
Query: 151 TQLVWATSSQLGCGRHLCSA----GQAAIEA--FVCAYSPRGNWEVNGKTIVPYKKGAWC 204
TQ+VWAT++++GC + C G+ A FVC YSP+GNW PYK G C
Sbjct: 163 TQIVWATTNKIGCAVNTCRKMTVWGEVWENAVYFVCNYSPKGNWIGE----APYKNGRPC 218
Query: 205 SLCTASVSG 213
S C S G
Sbjct: 219 SECPPSYGG 227
>gi|7705676 protease inhibitor 15 preproprotein [Homo sapiens]
Length = 258
Score = 93.2 bits (230), Expect = 4e-19
Identities = 63/187 (33%), Positives = 93/187 (49%), Gaps = 26/187 (13%)
Query: 43 LNRKESFLLLSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALC-GTPTPSLASGLW 101
+++ + +L HN++R V PPAA+M + W ++LA+ A+A AA C PS L
Sbjct: 62 ISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAEAWAATCIWDHGPSY---LL 118
Query: 102 RTLQVGWNMQLLPAGLVSFVEVVSLWFAEGQRYSHAAGECAR--------NATCTHYTQL 153
R L G N+ + S +++V W+ E + Y+ + CTHYTQ+
Sbjct: 119 RFL--GQNLSVRTGRYRSILQLVKPWYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQM 176
Query: 154 VWATSSQLGCGRHLC-------SAGQAAIEAFVCAYSPRGNWEVNGKTIVPYKKGAWCSL 206
VWATS+++GC H C S + A+ VC Y+P+GNW PYK G CS
Sbjct: 177 VWATSNRIGCAIHTCQNMNVWGSVWRRAV-YLVCNYAPKGNWIGE----APYKVGVPCSS 231
Query: 207 CTASVSG 213
C S G
Sbjct: 232 CPPSYGG 238
>gi|22749527 GLI pathogenesis-related 1 like 1 [Homo sapiens]
Length = 233
Score = 92.4 bits (228), Expect = 7e-19
Identities = 59/164 (35%), Positives = 82/164 (50%), Gaps = 15/164 (9%)
Query: 52 LSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALCGTPTPSLASGLWRTL----QVG 107
+ HN R V PPAADM+ + W LA++A+A A C ++ VG
Sbjct: 38 IEAHNEWRGKVNPPAADMKYMIWDKGLAKMAKAWANQCKFEHNDCLDKSYKCYAAFEYVG 97
Query: 108 WNMQLLPAGLVSFV--EVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGR 165
N+ L G+ SF ++ W+ E Q Y + C+R C HYTQLVWA S +GC
Sbjct: 98 ENIWL--GGIKSFTPRHAITAWYNETQFYDFDSLSCSR--VCGHYTQLVWANSFYVGCAV 153
Query: 166 HLC-SAGQAAIEAFVCAYSPRGNWEVNGKTIVPYKKGAWCSLCT 208
+C + G A+ FVC Y P GN+ + PY +G CSLC+
Sbjct: 154 AMCPNLGGASTAIFVCNYGPAGNF----ANMPPYVRGESCSLCS 193
>gi|30425410 R3H domain containing-like [Homo sapiens]
Length = 253
Score = 90.9 bits (224), Expect = 2e-18
Identities = 66/188 (35%), Positives = 88/188 (46%), Gaps = 32/188 (17%)
Query: 51 LLSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALCGTPTPSLASGLWRTLQ-VGWN 109
LL HN +R+ V PPAA+M + W LA+ A+A A C A G + ++ VG N
Sbjct: 66 LLDYHNHIRASVYPPAANMEYMVWDKRLARAAEAWATQC-----IWAHGPSQLMRYVGQN 120
Query: 110 MQLLPAGLVSFVEVVSLWFAEGQRY---------SHAAGECARNATCTHYTQLVWATSSQ 160
+ + S V+++ W E Y H C TC+HYTQ+VWA+S++
Sbjct: 121 LSIHSGQYRSVVDLMKSWSEEKWHYLFPAPRDCNPHCPWRCD-GPTCSHYTQMVWASSNR 179
Query: 161 LGCGRHLCSA----GQAAIEA--FVCAYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSG- 213
LGC H CS+ G A VC Y+ +GNW PYK G CS C S G
Sbjct: 180 LGCAIHTCSSISVWGNTWHRAAYLVCNYAIKGNWIGES----PYKMGKPCSSCPPSYQGS 235
Query: 214 -----CFK 216
CFK
Sbjct: 236 CNSNMCFK 243
>gi|5174675 cysteine-rich secretory protein 3 [Homo sapiens]
Length = 245
Score = 90.5 bits (223), Expect = 3e-18
Identities = 52/157 (33%), Positives = 77/157 (49%), Gaps = 4/157 (2%)
Query: 51 LLSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALCGTPTPSLASGLWRTLQVGWNM 110
+++ HN LR V PPA +M +++W+ A AQ A C S +L+ G N+
Sbjct: 42 IVNKHNELRRAVSPPARNMLKMEWNKEAAANAQKWANQCNY-RHSNPKDRMTSLKCGENL 100
Query: 111 QLLPAGLVSFVEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSA 170
+ A S+ + + WF E + G NA HYTQ+VW +S +GCG C
Sbjct: 101 YMSSASS-SWSQAIQSWFDEYNDFDFGVGPKTPNAVVGHYTQVVWYSSYLVGCGNAYCPN 159
Query: 171 GQAAIEAFVCAYSPRGNWEVNGKTIVPYKKGAWCSLC 207
+ +VC Y P GNW + VPY++GA C+ C
Sbjct: 160 QKVLKYYYVCQYCPAGNWA--NRLYVPYEQGAPCASC 194
>gi|13899303 cysteine-rich secretory protein LCCL domain containing
1 [Homo sapiens]
Length = 500
Score = 86.7 bits (213), Expect = 4e-17
Identities = 62/179 (34%), Positives = 84/179 (46%), Gaps = 26/179 (14%)
Query: 51 LLSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALC--GTPTPSLASGLWRTLQVGW 108
+L LHN+LRS V P A++M + W L + A++ A C SL + + L W
Sbjct: 65 ILDLHNKLRSQVYPTASNMEYMTWDVELERSAESWAESCLWEHGPASLLPSIGQNLGAHW 124
Query: 109 NMQLLPAGLVSFVEVVSLWFAEGQRYSHA-AGEC-------ARNATCTHYTQLVWATSSQ 160
P V W+ E + +S+ EC CTHYTQ+VWATS++
Sbjct: 125 GRYRPPTFHVQS------WYDEVKDFSYPYEHECNPYCPFRCSGPVCTHYTQVVWATSNR 178
Query: 161 LGCGRHLCSA----GQAAIEA--FVCAYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSG 213
+GC +LC GQ +A VC YSP+GNW + PYK G CS C S G
Sbjct: 179 IGCAINLCHNMNIWGQIWPKAVYLVCNYSPKGNWWGH----APYKHGRPCSACPPSFGG 233
>gi|215422434 cysteine-rich secretory protein 2 [Homo sapiens]
Length = 243
Score = 83.6 bits (205), Expect = 3e-16
Identities = 60/201 (29%), Positives = 95/201 (47%), Gaps = 19/201 (9%)
Query: 51 LLSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALCGTPTPSLASGLWRTLQVGWNM 110
+++ HN LR V PPA++M +++WS + AQ A C T S + + G N+
Sbjct: 40 IVNKHNELRKAVSPPASNMLKMEWSREVTTNAQRWANKC-TLQHSDPEDRKTSTRCGENL 98
Query: 111 QLLPAGLVSFVEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSA 170
+ + S+ + W+ E + + G + NA HYTQLVW ++ Q+GCG C
Sbjct: 99 YM-SSDPTSWSSAIQSWYDEILDFVYGVGPKSPNAVVGHYTQLVWYSTYQVGCGIAYCPN 157
Query: 171 GQAAIEAFVCAYSPRGNWEVNGKTIVPYKKGAWCS---------LCTAS------VSGCF 215
+ +VC Y P GN +N K PY++G C+ LCT S +S C
Sbjct: 158 QDSLKYYYVCQYCPAGN-NMNRKN-TPYQQGTPCAGCPDDCDKGLCTNSCQYQDLLSNCD 215
Query: 216 KAWDHAGGLCEVPRNPCRMSC 236
+ AG E+ + C+ +C
Sbjct: 216 SLKNTAGCEHELLKEKCKATC 236
>gi|215422430 cysteine-rich secretory protein 2 [Homo sapiens]
Length = 243
Score = 83.6 bits (205), Expect = 3e-16
Identities = 60/201 (29%), Positives = 95/201 (47%), Gaps = 19/201 (9%)
Query: 51 LLSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALCGTPTPSLASGLWRTLQVGWNM 110
+++ HN LR V PPA++M +++WS + AQ A C T S + + G N+
Sbjct: 40 IVNKHNELRKAVSPPASNMLKMEWSREVTTNAQRWANKC-TLQHSDPEDRKTSTRCGENL 98
Query: 111 QLLPAGLVSFVEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSA 170
+ + S+ + W+ E + + G + NA HYTQLVW ++ Q+GCG C
Sbjct: 99 YM-SSDPTSWSSAIQSWYDEILDFVYGVGPKSPNAVVGHYTQLVWYSTYQVGCGIAYCPN 157
Query: 171 GQAAIEAFVCAYSPRGNWEVNGKTIVPYKKGAWCS---------LCTAS------VSGCF 215
+ +VC Y P GN +N K PY++G C+ LCT S +S C
Sbjct: 158 QDSLKYYYVCQYCPAGN-NMNRKN-TPYQQGTPCAGCPDDCDKGLCTNSCQYQDLLSNCD 215
Query: 216 KAWDHAGGLCEVPRNPCRMSC 236
+ AG E+ + C+ +C
Sbjct: 216 SLKNTAGCEHELLKEKCKATC 236
>gi|4507671 cysteine-rich secretory protein 2 [Homo sapiens]
Length = 243
Score = 83.6 bits (205), Expect = 3e-16
Identities = 60/201 (29%), Positives = 95/201 (47%), Gaps = 19/201 (9%)
Query: 51 LLSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALCGTPTPSLASGLWRTLQVGWNM 110
+++ HN LR V PPA++M +++WS + AQ A C T S + + G N+
Sbjct: 40 IVNKHNELRKAVSPPASNMLKMEWSREVTTNAQRWANKC-TLQHSDPEDRKTSTRCGENL 98
Query: 111 QLLPAGLVSFVEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSA 170
+ + S+ + W+ E + + G + NA HYTQLVW ++ Q+GCG C
Sbjct: 99 YM-SSDPTSWSSAIQSWYDEILDFVYGVGPKSPNAVVGHYTQLVWYSTYQVGCGIAYCPN 157
Query: 171 GQAAIEAFVCAYSPRGNWEVNGKTIVPYKKGAWCS---------LCTAS------VSGCF 215
+ +VC Y P GN +N K PY++G C+ LCT S +S C
Sbjct: 158 QDSLKYYYVCQYCPAGN-NMNRKN-TPYQQGTPCAGCPDDCDKGLCTNSCQYQDLLSNCD 215
Query: 216 KAWDHAGGLCEVPRNPCRMSC 236
+ AG E+ + C+ +C
Sbjct: 216 SLKNTAGCEHELLKEKCKATC 236
>gi|215490058 cysteine-rich secretory protein 2 [Homo sapiens]
Length = 243
Score = 83.6 bits (205), Expect = 3e-16
Identities = 60/201 (29%), Positives = 95/201 (47%), Gaps = 19/201 (9%)
Query: 51 LLSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALCGTPTPSLASGLWRTLQVGWNM 110
+++ HN LR V PPA++M +++WS + AQ A C T S + + G N+
Sbjct: 40 IVNKHNELRKAVSPPASNMLKMEWSREVTTNAQRWANKC-TLQHSDPEDRKTSTRCGENL 98
Query: 111 QLLPAGLVSFVEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSA 170
+ + S+ + W+ E + + G + NA HYTQLVW ++ Q+GCG C
Sbjct: 99 YM-SSDPTSWSSAIQSWYDEILDFVYGVGPKSPNAVVGHYTQLVWYSTYQVGCGIAYCPN 157
Query: 171 GQAAIEAFVCAYSPRGNWEVNGKTIVPYKKGAWCS---------LCTAS------VSGCF 215
+ +VC Y P GN +N K PY++G C+ LCT S +S C
Sbjct: 158 QDSLKYYYVCQYCPAGN-NMNRKN-TPYQQGTPCAGCPDDCDKGLCTNSCQYQDLLSNCD 215
Query: 216 KAWDHAGGLCEVPRNPCRMSC 236
+ AG E+ + C+ +C
Sbjct: 216 SLKNTAGCEHELLKEKCKATC 236
>gi|215490018 cysteine-rich secretory protein 2 [Homo sapiens]
Length = 243
Score = 83.6 bits (205), Expect = 3e-16
Identities = 60/201 (29%), Positives = 95/201 (47%), Gaps = 19/201 (9%)
Query: 51 LLSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALCGTPTPSLASGLWRTLQVGWNM 110
+++ HN LR V PPA++M +++WS + AQ A C T S + + G N+
Sbjct: 40 IVNKHNELRKAVSPPASNMLKMEWSREVTTNAQRWANKC-TLQHSDPEDRKTSTRCGENL 98
Query: 111 QLLPAGLVSFVEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSA 170
+ + S+ + W+ E + + G + NA HYTQLVW ++ Q+GCG C
Sbjct: 99 YM-SSDPTSWSSAIQSWYDEILDFVYGVGPKSPNAVVGHYTQLVWYSTYQVGCGIAYCPN 157
Query: 171 GQAAIEAFVCAYSPRGNWEVNGKTIVPYKKGAWCS---------LCTAS------VSGCF 215
+ +VC Y P GN +N K PY++G C+ LCT S +S C
Sbjct: 158 QDSLKYYYVCQYCPAGN-NMNRKN-TPYQQGTPCAGCPDDCDKGLCTNSCQYQDLLSNCD 215
Query: 216 KAWDHAGGLCEVPRNPCRMSC 236
+ AG E+ + C+ +C
Sbjct: 216 SLKNTAGCEHELLKEKCKATC 236
>gi|110825980 GLI pathogenesis-related 1 precursor [Homo sapiens]
Length = 266
Score = 82.8 bits (203), Expect = 6e-16
Identities = 55/166 (33%), Positives = 79/166 (47%), Gaps = 22/166 (13%)
Query: 54 LHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALCG-------TPTPSLASGLWRTLQV 106
+HN+ RS V+P A+DM + W +LAQ+A+A A+ C P L +
Sbjct: 40 IHNKFRSEVKPTASDMLYMTWDPALAQIAKAWASNCQFSHNTRLKPPHKLHPNF---TSL 96
Query: 107 GWNMQLLPAGLVSFVEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRH 166
G N+ + S ++ W+ E Q Y C + C HYTQ+VWA S ++GC
Sbjct: 97 GENIWTGSVPIFSVSSAITNWYDEIQDYDFKTRICKK--VCGHYTQVVWADSYKVGCAVQ 154
Query: 167 LCS--AGQAAIE---AFVCAYSPRGNWEVNGKTIVPYKKGAWCSLC 207
C +G A+ F+C Y P GN+ PYK+GA CS C
Sbjct: 155 FCPKVSGFDALSNGAHFICNYGPGGNYPT-----WPYKRGATCSAC 195
>gi|25121982 acidic epididymal glycoprotein-like 1 isoform 1
precursor [Homo sapiens]
Length = 249
Score = 79.7 bits (195), Expect = 5e-15
Identities = 65/216 (30%), Positives = 96/216 (44%), Gaps = 19/216 (8%)
Query: 51 LLSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALCG-TPTPSLASGLWRTLQVGWN 109
++++HN LR V PPA++M ++ WS+ AQ A+ + C T + L L T G N
Sbjct: 44 IVNIHNALRRRVVPPASNMLKMSWSEEAAQNARIFSKYCDMTESNPLERRLPNTF-CGEN 102
Query: 110 MQLLPAGLVSFVEVVSLWFAEGQRYSHAAGECARN-ATCTHYTQLVWATSSQLGCGRHLC 168
M + VS+ V+ +W++E + H + T HYTQ+VWATS +GC C
Sbjct: 103 MHMTSYP-VSWSSVIGVWYSESTSFKHGEWTTTDDDITTDHYTQIVWATSYLIGCAIASC 161
Query: 169 SAGQAAIEAFVCAYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVP 228
+ +VC Y GN + K PYK G C C S C LC
Sbjct: 162 RQQGSPRYLYVCHYCHEGN-DPETKN-EPYKTGVPCEACP---SNC------EDKLC--- 207
Query: 229 RNPCRMSCQNHGRLNISTCHCHCPPGYTGRYCQVRC 264
NPC + + +I + C T +C+ C
Sbjct: 208 TNPC-IYYDEYFDCDIQVHYLGCNHSTTILFCKATC 242
>gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens]
Length = 1321
Score = 71.2 bits (173), Expect = 2e-12
Identities = 54/218 (24%), Positives = 86/218 (39%), Gaps = 40/218 (18%)
Query: 236 CQNHGRLNISTCH-------CHCPPGYTGRYCQVR-----CSLQCVHGRFREEECS---C 280
C+N+ L+ TC+ C C G+ G C++ CS C +G +E + C
Sbjct: 1012 CENNPCLHGGTCNANGTMYGCSCDQGFAGENCEIDIDDCLCS-PCENGGTCIDEVNGFVC 1070
Query: 281 VCDIGYGGAQCATKVHFPFHTCDL---RIDGDCFMVSSEADTYYRARMKCQRKGGVLAQI 337
+C YGG+ C CD + G C+ + + A C+R+ G L +
Sbjct: 1071 LCLPSYGGSFCEKDTE----GCDRGWHKFQGHCYRYFAHRRAWEDAEKDCRRRSGHLTSV 1126
Query: 338 KSQKVQDILAFYLGRLETTNEVIDSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAF 397
S + + + F N WIGL + + F+W F ++
Sbjct: 1127 HSPEEHSFI---------------NSFGHENTWIGLNDRIVERDFQWTDNTGLQFENWRE 1171
Query: 398 GQPDNH--GFGNCVELQASAAFNWNDQRCKTRNRYICQ 433
QPDN G +CV + A + WND C Y+C+
Sbjct: 1172 NQPDNFFAGGEDCVVMVAHESGRWNDVPCNYNLPYVCK 1209
>gi|25121984 acidic epididymal glycoprotein-like 1 isoform 2
precursor [Homo sapiens]
Length = 178
Score = 70.1 bits (170), Expect = 4e-12
Identities = 44/134 (32%), Positives = 69/134 (51%), Gaps = 4/134 (2%)
Query: 51 LLSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALCG-TPTPSLASGLWRTLQVGWN 109
++++HN LR V PPA++M ++ WS+ AQ A+ + C T + L L T G N
Sbjct: 44 IVNIHNALRRRVVPPASNMLKMSWSEEAAQNARIFSKYCDMTESNPLERRLPNTF-CGEN 102
Query: 110 MQLLPAGLVSFVEVVSLWFAEGQRYSHAAGECA-RNATCTHYTQLVWATSSQLGCGRHLC 168
M + + VS+ V+ +W++E + H + T HYTQ+VWATS +GC C
Sbjct: 103 MH-MTSYPVSWSSVIGVWYSESTSFKHGEWTTTDDDITTDHYTQIVWATSYLIGCAIASC 161
Query: 169 SAGQAAIEAFVCAY 182
+ +VC Y
Sbjct: 162 RQQGSPRYLYVCHY 175
>gi|4505245 mannose receptor C type 1 precursor [Homo sapiens]
Length = 1456
Score = 69.3 bits (168), Expect = 7e-12
Identities = 38/119 (31%), Positives = 63/119 (52%), Gaps = 10/119 (8%)
Query: 316 EADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFETRNFWIGLTY 375
E T++ +R C+ GG LA I +++ Q + RL T S + FW+GLTY
Sbjct: 669 EKKTWFESRDFCRALGGDLASINNKEEQQTI----WRLITA-----SGSYHKLFWLGLTY 719
Query: 376 KTAKDSFRWATGEHQAFTSFAFGQPDNH-GFGNCVELQASAAFNWNDQRCKTRNRYICQ 433
+ + F W+ G ++ ++A+G+P+N+ C EL+ +WND C+ N +ICQ
Sbjct: 720 GSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQ 778
Score = 52.8 bits (125), Expect = 6e-07
Identities = 37/124 (29%), Positives = 58/124 (46%), Gaps = 13/124 (10%)
Query: 311 FMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFETRNFW 370
+ S E +T AR C+R G L I+S+ + L Y+ R + + ++
Sbjct: 812 YYFSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQSA----------YF 861
Query: 371 IGLTYKTAKDSFRWATGEHQAFTSFAFGQPD-NHGFGNCVELQASAAFNWNDQRCKTRNR 429
IGL K F W G + S+A G+P+ + NCV + +++ F WND C N
Sbjct: 862 IGLLISLDK-KFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGF-WNDINCGYPNA 919
Query: 430 YICQ 433
+ICQ
Sbjct: 920 FICQ 923
Score = 47.4 bits (111), Expect = 3e-05
Identities = 36/137 (26%), Positives = 56/137 (40%), Gaps = 25/137 (18%)
Query: 310 CFMV----SSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFE 365
CF + E + AR C GG L I+++K Q L +++ DS F
Sbjct: 956 CFKIFGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMK---------DSTFS 1006
Query: 366 TRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPD------NHGFGNCVELQASA---A 416
W GL ++ +F W G +T++ G P ++ +CV + A A
Sbjct: 1007 A---WTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGGASNEA 1063
Query: 417 FNWNDQRCKTRNRYICQ 433
W D C ++ YICQ
Sbjct: 1064 GKWMDDTCDSKRGYICQ 1080
Score = 45.1 bits (105), Expect = 1e-04
Identities = 34/129 (26%), Positives = 58/129 (44%), Gaps = 15/129 (11%)
Query: 308 GDCFMVSSEADTYYR-ARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFET 366
G C+ + + R A C+++GG L I + + D + LG E +E+
Sbjct: 371 GHCYKIHRDEKKIQRDALTTCRKEGGDLTSIHTIEELDFIISQLG-YEPNDEL------- 422
Query: 367 RNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQP--DNHGFGNCVELQASAAFNWNDQRC 424
WIGL + F W+ G FT + G+P +N+ +CV ++ + W D+ C
Sbjct: 423 ---WIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGY-WADRGC 478
Query: 425 KTRNRYICQ 433
+ YIC+
Sbjct: 479 EWPLGYICK 487
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/132 (21%), Positives = 52/132 (39%), Gaps = 14/132 (10%)
Query: 310 CFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFETRNF 369
C+M+ T+ A C + L I+ + Q L ++G + F
Sbjct: 515 CYMIGHTLSTFAEANQTCNNENAYLTTIEDRYEQAFLTSFVGLRPE-----------KYF 563
Query: 370 WIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNHGFGNCVELQASAAFN-WNDQRCKTRN 428
W GL+ K +F+W E FT + P CV ++ A W+ +C +
Sbjct: 564 WTGLSDIQTKGTFQWTIEEEVRFTHWNSDMPGRK--PGCVAMRTGIAGGLWDVLKCDEKA 621
Query: 429 RYICQFAQEHIS 440
+++C+ E ++
Sbjct: 622 KFVCKHWAEGVT 633
Score = 41.6 bits (96), Expect = 0.001
Identities = 28/120 (23%), Positives = 44/120 (36%), Gaps = 12/120 (10%)
Query: 314 SSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFETRNFWIGL 373
S A T+++AR CQ++ L I Q L L T WIGL
Sbjct: 234 SKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSL------------TSGLWIGL 281
Query: 374 TYKTAKDSFRWATGEHQAFTSFAFGQPDNHGFGNCVELQASAAFNWNDQRCKTRNRYICQ 433
+ ++W+ + ++ G P +CV L W + C + YIC+
Sbjct: 282 NSLSFNSGWQWSDRSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQKLGYICK 341
>gi|57546917 mannose receptor, C type 1-like 1 [Homo sapiens]
Length = 1456
Score = 69.3 bits (168), Expect = 7e-12
Identities = 38/119 (31%), Positives = 63/119 (52%), Gaps = 10/119 (8%)
Query: 316 EADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFETRNFWIGLTY 375
E T++ +R C+ GG LA I +++ Q + RL T S + FW+GLTY
Sbjct: 669 EKKTWFESRDFCRALGGDLASINNKEEQQTI----WRLITA-----SGSYHKLFWLGLTY 719
Query: 376 KTAKDSFRWATGEHQAFTSFAFGQPDNH-GFGNCVELQASAAFNWNDQRCKTRNRYICQ 433
+ + F W+ G ++ ++A+G+P+N+ C EL+ +WND C+ N +ICQ
Sbjct: 720 GSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQ 778
Score = 52.8 bits (125), Expect = 6e-07
Identities = 37/124 (29%), Positives = 58/124 (46%), Gaps = 13/124 (10%)
Query: 311 FMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFETRNFW 370
+ S E +T AR C+R G L I+S+ + L Y+ R + + ++
Sbjct: 812 YYFSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQSA----------YF 861
Query: 371 IGLTYKTAKDSFRWATGEHQAFTSFAFGQPD-NHGFGNCVELQASAAFNWNDQRCKTRNR 429
IGL K F W G + S+A G+P+ + NCV + +++ F WND C N
Sbjct: 862 IGLLISLDK-KFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGF-WNDINCGYPNA 919
Query: 430 YICQ 433
+ICQ
Sbjct: 920 FICQ 923
Score = 47.4 bits (111), Expect = 3e-05
Identities = 36/137 (26%), Positives = 56/137 (40%), Gaps = 25/137 (18%)
Query: 310 CFMV----SSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFE 365
CF + E + AR C GG L I+++K Q L +++ DS F
Sbjct: 956 CFKIFGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMK---------DSTFS 1006
Query: 366 TRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPD------NHGFGNCVELQASA---A 416
W GL ++ +F W G +T++ G P ++ +CV + A A
Sbjct: 1007 A---WTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGGASNEA 1063
Query: 417 FNWNDQRCKTRNRYICQ 433
W D C ++ YICQ
Sbjct: 1064 GKWMDDTCDSKRGYICQ 1080
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/132 (21%), Positives = 52/132 (39%), Gaps = 14/132 (10%)
Query: 310 CFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFETRNF 369
C+M+ T+ A C + L I+ + Q L ++G + F
Sbjct: 515 CYMIGHTLSTFAEANQTCNNENAYLTTIEDRYEQAFLTSFVGLRPE-----------KYF 563
Query: 370 WIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNHGFGNCVELQASAAFN-WNDQRCKTRN 428
W GL+ K +F+W E FT + P CV ++ A W+ +C +
Sbjct: 564 WTGLSDIQTKGTFQWTIEEEVRFTHWNSDMPGRK--PGCVAMRTGIAGGLWDVLKCDEKA 621
Query: 429 RYICQFAQEHIS 440
+++C+ E ++
Sbjct: 622 KFVCKHWAEGVT 633
Score = 43.9 bits (102), Expect = 3e-04
Identities = 34/129 (26%), Positives = 58/129 (44%), Gaps = 15/129 (11%)
Query: 308 GDCFMVSSEADTYYR-ARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFET 366
G C+ + + R A C+++G LA I + + D + LG E +E+
Sbjct: 371 GHCYKIHRDEKKIQRDALTTCRKEGSDLASIHTIEEFDFIISQLG-YEPNDEL------- 422
Query: 367 RNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQP--DNHGFGNCVELQASAAFNWNDQRC 424
WIGL + F W+ G FT + G+P +N+ +CV ++ + W D+ C
Sbjct: 423 ---WIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGY-WADRGC 478
Query: 425 KTRNRYICQ 433
+ YIC+
Sbjct: 479 EWPLGYICK 487
Score = 41.6 bits (96), Expect = 0.001
Identities = 28/120 (23%), Positives = 44/120 (36%), Gaps = 12/120 (10%)
Query: 314 SSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFETRNFWIGL 373
S A T+++AR CQ++ L I Q L L T WIGL
Sbjct: 234 SKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSL------------TSGLWIGL 281
Query: 374 TYKTAKDSFRWATGEHQAFTSFAFGQPDNHGFGNCVELQASAAFNWNDQRCKTRNRYICQ 433
+ ++W+ + ++ G P +CV L W + C + YIC+
Sbjct: 282 NSLSFNSGWQWSDRSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQKLGYICK 341
>gi|187607300 versican isoform 2 [Homo sapiens]
Length = 655
Score = 67.0 bits (162), Expect = 3e-11
Identities = 66/244 (27%), Positives = 94/244 (38%), Gaps = 63/244 (25%)
Query: 214 CFKAWDHAGGLCEVPRNPCRMSCQNHGRLNISTCH-------CHCPPGYTGRYCQV---- 262
CFK D C++ NPC LN TC+ C C PGY+G C++
Sbjct: 345 CFKRPDR----CKM--NPC---------LNGGTCYPTETSYVCTCVPGYSGDQCELDFDE 389
Query: 263 ------RCSLQCVHG--RFREEECSCVCDIGYGGAQCATKVHFPFHTCDL---RIDGDCF 311
R CV G FR C+C Y GA C TCD + G C+
Sbjct: 390 CHSNPCRNGATCVDGFNTFR-----CLCLPSYVGALCEQDTE----TCDYGWHKFQGQCY 440
Query: 312 MVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFETRNFWI 371
+ T+ A +C+ +G L I S + Q ++ R + D++ WI
Sbjct: 441 KYFAHRRTWDAAERECRLQGAHLTSILSHEEQ----MFVNR-------VGHDYQ----WI 485
Query: 372 GLTYKTAKDSFRWATGEHQAFTSFAFGQPDN--HGFGNCVELQASAAFNWNDQRCKTRNR 429
GL K + FRW G + ++ QPD+ +CV + WND C
Sbjct: 486 GLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYHLT 545
Query: 430 YICQ 433
Y C+
Sbjct: 546 YTCK 549
>gi|21361116 versican isoform 1 [Homo sapiens]
Length = 3396
Score = 66.2 bits (160), Expect = 6e-11
Identities = 59/222 (26%), Positives = 87/222 (39%), Gaps = 48/222 (21%)
Query: 236 CQNHGRLNISTCH-------CHCPPGYTGRYCQV----------RCSLQCVHG--RFREE 276
C+ + LN TC+ C C PGY+G C++ R CV G FR
Sbjct: 3093 CKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR-- 3150
Query: 277 ECSCVCDIGYGGAQCATKVHFPFHTCDL---RIDGDCFMVSSEADTYYRARMKCQRKGGV 333
C+C Y GA C TCD + G C+ + T+ A +C+ +G
Sbjct: 3151 ---CLCLPSYVGALCEQDTE----TCDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAH 3203
Query: 334 LAQIKSQKVQDILAFYLGRLETTNEVIDSDFETRNFWIGLTYKTAKDSFRWATGEHQAFT 393
L I S + Q ++ R + D++ WIGL K + FRW G +
Sbjct: 3204 LTSILSHEEQ----MFVNR-------VGHDYQ----WIGLNDKMFEHDFRWTDGSTLQYE 3248
Query: 394 SFAFGQPDN--HGFGNCVELQASAAFNWNDQRCKTRNRYICQ 433
++ QPD+ +CV + WND C Y C+
Sbjct: 3249 NWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYHLTYTCK 3290
>gi|22748923 GLI pathogenesis-related 1 like 2 [Homo sapiens]
Length = 253
Score = 65.9 bits (159), Expect = 7e-11
Identities = 47/162 (29%), Positives = 75/162 (46%), Gaps = 13/162 (8%)
Query: 52 LSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALC----GTPTPSLASGLWRTLQVG 107
++LHN LR V P +++R + W +L++ A+A C + + +G
Sbjct: 58 VNLHNELRGDVIPRGSNLRFMTWDVALSRTARAWGKKCLFTHNIYLQDVQMVHPKFYGIG 117
Query: 108 WNMQLLPAGLVSFVEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHL 167
NM + P + + W AE + Y+ G C + C++Y QLVW S ++GC
Sbjct: 118 ENMWVGPENEFTASIAIRSWHAEKKMYNFENGSC--SGDCSNYIQLVWDHSYKVGCAVTP 175
Query: 168 CSAGQAAIEA--FVCAYSPRGNWEVNGKTIVPYKKGAWCSLC 207
CS I A F+C Y+P G T PY+ G +C+ C
Sbjct: 176 CSKIGHIIHAAIFICNYAPGGT-----LTRRPYEPGIFCTRC 212
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 62.8 bits (151), Expect = 6e-10
Identities = 50/180 (27%), Positives = 66/180 (36%), Gaps = 37/180 (20%)
Query: 136 HAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQAAIEAFVCAYSPRGNWEVNGKTI 195
H +C ATC H T G C G AF P G +
Sbjct: 192 HQRCQCQNGATCDHVT------------GECRCPPGYTG--AFCEDLCPPGKHGPQCEQR 237
Query: 196 VPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVP------RNPCRMSCQNH--GRLNISTC 247
P + G C T S C W G +C P C CQ H G + +T
Sbjct: 238 CPCQNGGVCHHVTGECS-CPSGW--MGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATG 294
Query: 248 HCHCPPGYTGRYCQVRC-----------SLQCVH-GRFREEECSCVCDIGYGGAQCATKV 295
CHC PGYTG CQ C + QCV+ G+ +C+C+ G+ G +C ++
Sbjct: 295 QCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARL 354
Score = 44.3 bits (103), Expect = 2e-04
Identities = 49/193 (25%), Positives = 65/193 (33%), Gaps = 47/193 (24%)
Query: 131 GQRYSHAAGECARNA-TCTHYTQLVWATSSQLGCGRHLCSAGQAAIEAFVCAYSPRGNWE 189
G R S +C ++ C H T L G LC+ VC P G +
Sbjct: 621 GHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGA---LCNE--------VC---PSGRFG 666
Query: 190 VNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHGRLNISTCHC 249
N I C+ S C+ W G C P P G I TC+C
Sbjct: 667 KNCAGICTCTNNGTCNPIDRSCQ-CYPGW--IGSDCSQPCPPAHW-----GPNCIHTCNC 718
Query: 250 H-------------CPPGYTGRYCQVRCSLQCVHGRFREEECSCVC------DIGYGGAQ 290
H C PG+TG YC RC L F ++C+ +C D + Q
Sbjct: 719 HNGAFCSAYDGECKCTPGWTGLYCTQRCPL-----GFYGKDCALICQCQNGADCDHISGQ 773
Query: 291 CATKVHFPFHTCD 303
C + F C+
Sbjct: 774 CTCRTGFMGRHCE 786
Score = 41.2 bits (95), Expect = 0.002
Identities = 32/110 (29%), Positives = 45/110 (40%), Gaps = 19/110 (17%)
Query: 190 VNGKTIVPY----KKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHGRLNIS 245
V+G+ I P + G + C+++ G DH G C R C+N N
Sbjct: 114 VHGRCIAPNTCQCEPGWGGTNCSSACDG-----DHWGPHCT-----SRCQCKNGALCNPI 163
Query: 246 TCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSC----VCDIGYGGAQC 291
T CHC G+ G C+ RC Q +G + C C CD G +C
Sbjct: 164 TGACHCAAGFRGWRCEDRCE-QGTYGNDCHQRCQCQNGATCDHVTGECRC 212
Score = 40.8 bits (94), Expect = 0.003
Identities = 41/155 (26%), Positives = 56/155 (36%), Gaps = 33/155 (21%)
Query: 158 SSQLGC----------GRHLCSAGQAAIEAFVCAYSPRGNWEVNGKTIVPYKKGAWCSLC 207
SS+ GC G C AG ++ + P G W G C+
Sbjct: 453 SSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRC--PSGTWGFGCNLTCQCLNGGACNTL 510
Query: 208 TASVSGCFKAWDHAGGLCEVPRNP------C--RMSCQNHGRLNISTCHCHCPPGYTGRY 259
+ + C W G CE+P C R C + + +T HC C PG++G
Sbjct: 511 DGTCT-CAPGW--RGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSG-- 565
Query: 260 CQVRCSLQCVHGRFREEECS--CVCDIGYGGAQCA 292
V C C GR+ CS C C GA C+
Sbjct: 566 --VHCDSVCAEGRW-GPNCSLPCYCK---NGASCS 594
Score = 40.0 bits (92), Expect = 0.004
Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 3/57 (5%)
Query: 239 HGRLNISTCHCHCPPGY--TGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCAT 293
HG + C PG+ +G C C+ +CVHGR +C C+ G+GG C++
Sbjct: 82 HGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIAPN-TCQCEPGWGGTNCSS 137
Score = 38.9 bits (89), Expect = 0.010
Identities = 33/99 (33%), Positives = 39/99 (39%), Gaps = 19/99 (19%)
Query: 211 VSG-CFKAWDHAGGLCEVPRNP-------CRMSCQNHGRLNISTCH-----CHCPPGYTG 257
VSG C AG CE P C C H N +CH C C PG++G
Sbjct: 335 VSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLE-NTHSCHPMSGECACKPGWSG 393
Query: 258 RYCQVRCSLQCVHGRFREEECSCV----CDIGYGGAQCA 292
YC CS +G ++ CSC CD G CA
Sbjct: 394 LYCNETCS-PGFYGEACQQICSCQNGADCDSVTGKCTCA 431
Score = 36.2 bits (82), Expect = 0.062
Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 16/74 (21%)
Query: 235 SCQNHGRLNISTCHCHCPPGYTGRYCQ---------VRCSLQCVHGRFREEEC-----SC 280
SCQN + T C C PG+ G C + CS +C G + C SC
Sbjct: 414 SCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRC--GCKNDAVCSPVDGSC 471
Query: 281 VCDIGYGGAQCATK 294
C G+ G C+ +
Sbjct: 472 TCKAGWHGVDCSIR 485
Score = 34.3 bits (77), Expect = 0.24
Identities = 32/130 (24%), Positives = 46/130 (35%), Gaps = 27/130 (20%)
Query: 184 PRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNP-------CRM-- 234
P +W N GA+CS C W GL R P C +
Sbjct: 704 PPAHWGPNCIHTCNCHNGAFCSAYDGECK-CTPGWT---GLYCTQRCPLGFYGKDCALIC 759
Query: 235 SCQNHGRLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCV------------- 281
CQN + + C C G+ GR+C+ +C +G + C C+
Sbjct: 760 QCQNGADCDHISGQCTCRTGFMGRHCEQKCP-SGTYGYGCRQICDCLNNSTCDHITGTCY 818
Query: 282 CDIGYGGAQC 291
C G+ GA+C
Sbjct: 819 CSPGWKGARC 828
Score = 33.9 bits (76), Expect = 0.31
Identities = 28/100 (28%), Positives = 35/100 (35%), Gaps = 24/100 (24%)
Query: 214 CFKAWD--HAGGLCEVPR------NPCRMSCQNHGRLNISTCHCHCPPGYTGRYCQVRCS 265
C W H +C R PC C+N + C C PG+ G CQ CS
Sbjct: 559 CLPGWSGVHCDSVCAEGRWGPNCSLPCY--CKNGASCSPDDGICECAPGFRGTTCQRICS 616
Query: 266 ------------LQCVHGRFREEECSCVCDI--GYGGAQC 291
QCVH + +CD G+ GA C
Sbjct: 617 PGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALC 656
Score = 33.5 bits (75), Expect = 0.40
Identities = 33/137 (24%), Positives = 45/137 (32%), Gaps = 27/137 (19%)
Query: 164 GRHLCSAGQAAIEAFVCAYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGG 223
G+ C+ G I+ P G + +N + K A CS S + C W
Sbjct: 426 GKCTCAPGFKGIDCSTPC--PLGTYGINCSSRCGCKNDAVCSPVDGSCT-CKAGWHGVDC 482
Query: 224 LCEVPRNP----CRMSCQ--NHGRLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEE 277
P C ++CQ N G N C C PG+ G E+
Sbjct: 483 SIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRG------------------EK 524
Query: 278 CSCVCDIGYGGAQCATK 294
C C G G CA +
Sbjct: 525 CELPCQDGTYGLNCAER 541
Score = 29.3 bits (64), Expect = 7.6
Identities = 28/94 (29%), Positives = 38/94 (40%), Gaps = 21/94 (22%)
Query: 212 SGCFKAWDHAGGLCEVPRNPCRMSCQNHGRLNISTCHCHCPPGYTGR------------- 258
S C + +G +C VP C C HGR I+ C C PG+ G
Sbjct: 92 SQCCPGFYESGEMC-VPH--CADKCV-HGRC-IAPNTCQCEPGWGGTNCSSACDGDHWGP 146
Query: 259 YCQVRCSLQCVHGRF-REEECSCVCDIGYGGAQC 291
+C RC QC +G +C C G+ G +C
Sbjct: 147 HCTSRC--QCKNGALCNPITGACHCAAGFRGWRC 178
>gi|116235485 delta-notch-like EGF repeat-containing transmembrane
[Homo sapiens]
Length = 737
Score = 59.3 bits (142), Expect = 7e-09
Identities = 54/171 (31%), Positives = 70/171 (40%), Gaps = 28/171 (16%)
Query: 146 TCTHYTQLVWATSSQL-GCGRHLCSAGQAAIEA--------FVCAYSPRGNWEVNGKTIV 196
+CT Q V + C R C + I+A F C P E+ I
Sbjct: 335 SCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKID 394
Query: 197 -----PYKKGAWCSLCTASVSG--CFKAWDHAGGLCEVPRNPCRMS-CQNHGRLNISTCH 248
P + GA C +S+SG C + G CE +PC S CQN+G + H
Sbjct: 395 YCILDPCRNGA---TCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVH 451
Query: 249 --CHCPPGYTGRYCQVR---CSLQ-CVHGRFREEECS--CVCDIGYGGAQC 291
C+C PG+TG C C+L C HG R S C+CD GY G C
Sbjct: 452 FTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPGYHGLYC 502
Score = 40.4 bits (93), Expect = 0.003
Identities = 36/127 (28%), Positives = 51/127 (40%), Gaps = 15/127 (11%)
Query: 200 KGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHG-------RLNISTCHCHCP 252
KG + + + C + G CE R CQN+ + + S C C
Sbjct: 322 KGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTCVCL 381
Query: 253 PGYTGRYCQVR---CSLQ-CVHGRFREEECS---CVCDIGYGGAQCATKVHFPFHTCDLR 305
PGYTG CQ + C L C +G S C C GY G+ C KV P + +
Sbjct: 382 PGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVD-PCASSPCQ 440
Query: 306 IDGDCFM 312
+G C++
Sbjct: 441 NNGTCYV 447
Score = 33.5 bits (75), Expect = 0.40
Identities = 18/53 (33%), Positives = 22/53 (41%), Gaps = 10/53 (18%)
Query: 249 CHCPPGYTGRYCQV----RCSLQCVHGRFREEECS------CVCDIGYGGAQC 291
C CP G +G CQ+ S C HG S C+C+ GY G C
Sbjct: 80 CTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNC 132
Score = 32.7 bits (73), Expect = 0.68
Identities = 24/95 (25%), Positives = 36/95 (37%), Gaps = 24/95 (25%)
Query: 220 HAGGLCEVPRNPCRMSCQNHGRLNISTCH---CHCPPGYTGRYCQVR------------- 263
+ G LC+ + C + +G IS+ C CP GY G C+ +
Sbjct: 384 YTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNG 443
Query: 264 -CSLQCVHGRFREEECSCVCDIGYGGAQCATKVHF 297
C + VH +C C G+ G CA + F
Sbjct: 444 TCYVDGVH-------FTCNCSPGFTGPTCAQLIDF 471
Score = 32.7 bits (73), Expect = 0.68
Identities = 16/60 (26%), Positives = 26/60 (43%), Gaps = 3/60 (5%)
Query: 214 CFKAWDHAGGLCEVPRNPCRMSCQNHGRLNIST---CHCHCPPGYTGRYCQVRCSLQCVH 270
C A G C++ N C + +HG + +CHCP G+ G C++ + H
Sbjct: 567 CICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHLQWKSGH 626
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 58.5 bits (140), Expect = 1e-08
Identities = 41/119 (34%), Positives = 54/119 (45%), Gaps = 11/119 (9%)
Query: 189 EVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPC-RMSCQNHGRL--NIS 245
++N P + GA C+ C S + C +G CE C SC N G I+
Sbjct: 945 DINECASDPCRNGANCTDCVDSYT-CTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGIN 1003
Query: 246 TCHCHCPPGYTGRYCQ---VRCSLQ-CVHGRFREEECS---CVCDIGYGGAQCATKVHF 297
+ C CPPG+TG YCQ C Q C+HG ++ C C C GY G C VH+
Sbjct: 1004 SFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHW 1062
Score = 49.7 bits (117), Expect = 5e-06
Identities = 52/192 (27%), Positives = 70/192 (36%), Gaps = 49/192 (25%)
Query: 131 GQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQAAIEAFVCAYSPRGNWEV 190
G H EC + C H + Q GCG + C+ P+G
Sbjct: 1015 GSYCQHDVNECD-SQPCLH------GGTCQDGCGSYRCTC-------------PQGYTGP 1054
Query: 191 NGKTIV------PYKKGAWC-SLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQN----- 238
N + +V P K G C T C W G C+VP C ++ Q
Sbjct: 1055 NCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGW--TGLYCDVPSVSCEVAAQRQGVDV 1112
Query: 239 -----HGRLNI---STCHCHCPPGYTGRYCQ---VRCS-LQCVHGRFREEEC---SCVCD 283
HG L + +T HC C GYTG YC+ CS C +G + SC C
Sbjct: 1113 ARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCV 1172
Query: 284 IGYGGAQCATKV 295
GY G C+ ++
Sbjct: 1173 AGYHGVNCSEEI 1184
Score = 46.6 bits (109), Expect = 5e-05
Identities = 34/108 (31%), Positives = 43/108 (39%), Gaps = 24/108 (22%)
Query: 207 CTASVSG--CFKAWDHAGGLCEVPRNPCRMS-CQNHGRLNISTCH----CHCPPGYTGRY 259
C V+G C + G CEV PC S C+N G S + C CP G+ G+
Sbjct: 806 CIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQT 865
Query: 260 CQV------------RCSLQCVHGRFREEECSCVCDIGYGGAQCATKV 295
C+V S Q HG +R C C GY G C T +
Sbjct: 866 CEVDINECVLSPCRHGASCQNTHGGYR-----CHCQAGYSGRNCETDI 908
Score = 45.4 bits (106), Expect = 1e-04
Identities = 35/113 (30%), Positives = 49/113 (43%), Gaps = 10/113 (8%)
Query: 188 WEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHGRLN--IS 245
++V+ P K GA C L + C + G CEV + C ++G ++
Sbjct: 527 YDVDECASTPCKNGAKC-LDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVA 585
Query: 246 TCHCHCPPGYTGRYCQV---RCSLQ-CVHG---RFREEECSCVCDIGYGGAQC 291
T C C PGYTG +C+ CS Q C HG + R+ C C G G C
Sbjct: 586 TFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNC 638
Score = 45.1 bits (105), Expect = 1e-04
Identities = 37/122 (30%), Positives = 48/122 (39%), Gaps = 11/122 (9%)
Query: 184 PRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMS-CQNHGRL 242
PR +VN P + A C L C + G CEV + C S C ++GR
Sbjct: 447 PRCEIDVNECVSNPCQNDATC-LDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRC 505
Query: 243 --NISTCHCHCPPGYTGRYCQVR----CSLQCVHGR---FREEECSCVCDIGYGGAQCAT 293
I+ C CP G+TG CQ S C +G +CVC GY G C
Sbjct: 506 LDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEV 565
Query: 294 KV 295
+
Sbjct: 566 DI 567
Score = 43.1 bits (100), Expect = 5e-04
Identities = 30/114 (26%), Positives = 47/114 (41%), Gaps = 13/114 (11%)
Query: 189 EVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMS-CQNHGRLN--IS 245
++N + P + GA C T C ++G CE + CR + C N G I+
Sbjct: 869 DINECVLSPCRHGASCQN-THGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGIN 927
Query: 246 TCHCHCPPGYTGRYCQVRCSLQCVHGRFRE--------EECSCVCDIGYGGAQC 291
T C C PG+ G +C+ + +C R + +C C G+ G C
Sbjct: 928 TAFCDCLPGFRGTFCEEDIN-ECASDPCRNGANCTDCVDSYTCTCPAGFSGIHC 980
Score = 41.6 bits (96), Expect = 0.001
Identities = 44/170 (25%), Positives = 59/170 (34%), Gaps = 37/170 (21%)
Query: 137 AAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQAAI-----EAFVCAYSPRGNWEVN 191
A+ C ATC H + G LC A I E C +P VN
Sbjct: 340 ASAACFHGATC-HDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNP-----VN 393
Query: 192 GKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMS--CQNHGRLNISTCHC 249
GK I G C+ V C + NPC + C N + + C
Sbjct: 394 GKAICTCPSGYTGPACSQDVDEC-----------SLGANPCEHAGKCIN----TLGSFEC 438
Query: 250 HCPPGYTGRYCQVRCSLQCVHGRFREE--------ECSCVCDIGYGGAQC 291
C GYTG C++ + +CV + + E C+C GY G C
Sbjct: 439 QCLQGYTGPRCEIDVN-ECVSNPCQNDATCLDQIGEFQCICMPGYEGVHC 487
Score = 40.0 bits (92), Expect = 0.004
Identities = 40/165 (24%), Positives = 59/165 (35%), Gaps = 47/165 (28%)
Query: 163 CGRHLCSAGQAA--IEAFVCAYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDH 220
C C +G I+ + CA P G S+C ++ C H
Sbjct: 645 CASSPCDSGTCLDKIDGYECACEP----------------GYTGSMCNINIDECAGNPCH 688
Query: 221 AGGLCE---------VPR-----------NPCRMSCQNHG--RLNISTCHCHCPPGYTGR 258
GG CE P N C + HG R +++ C C PG++G
Sbjct: 689 NGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGT 748
Query: 259 YCQV---RC-SLQCVHGRFREEECS---CVCDIGYGGAQCATKVH 296
C + C S CV+G ++ S C C G+ G C T ++
Sbjct: 749 NCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNIN 793
Score = 38.9 bits (89), Expect = 0.010
Identities = 30/111 (27%), Positives = 44/111 (39%), Gaps = 12/111 (10%)
Query: 197 PYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCR-MSCQNHGRL--NISTCHCHCPP 253
P + G C C G CE + C +C+N G ++T +C CPP
Sbjct: 226 PCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPP 285
Query: 254 GYTGRYCQV---RCSLQ---CVHG---RFREEECSCVCDIGYGGAQCATKV 295
+TG+YC C L C +G +CVC G+ G C+ +
Sbjct: 286 EWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENI 336
Score = 38.9 bits (89), Expect = 0.010
Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 9/84 (10%)
Query: 222 GGLCEVPRNPCRMS-CQNHGRL--NISTCHCHCPPGYTGRYCQV---RCSLQ-CVHGRFR 274
G LC+ + C + C+N + +T C C GYTG +C+V C C +G +
Sbjct: 522 GHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCK 581
Query: 275 EEECS--CVCDIGYGGAQCATKVH 296
+ + C+C GY G C T ++
Sbjct: 582 DGVATFTCLCRPGYTGHHCETNIN 605
Score = 37.4 bits (85), Expect = 0.028
Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 11/94 (11%)
Query: 214 CFKAWDHAGGLCEVPR-NPCRMS-CQNHGRLNISTC---HCHCPPGYTGRYCQVR---CS 265
C A +G LC P N C + C+N G ++ T C CPPG++G+ CQ S
Sbjct: 87 CSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCAS 146
Query: 266 LQCVHGRF---REEECSCVCDIGYGGAQCATKVH 296
C +G E C C + G C V+
Sbjct: 147 NPCANGGQCLPFEASYICHCPPSFHGPTCRQDVN 180
Score = 37.4 bits (85), Expect = 0.028
Identities = 20/46 (43%), Positives = 24/46 (52%), Gaps = 4/46 (8%)
Query: 220 HAGGLCEVPRNPCRMS-CQNHGRLNIS---TCHCHCPPGYTGRYCQ 261
H G CE P PC S CQN G + T C C PG+TG+ C+
Sbjct: 210 HTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCE 255
Score = 36.6 bits (83), Expect = 0.047
Identities = 26/92 (28%), Positives = 36/92 (39%), Gaps = 9/92 (9%)
Query: 214 CFKAWDHAGGLCEVPRNPCRMSCQNHGRL--NISTCHCHCPPGYTGRYCQVR----CSLQ 267
CF G CE+ + C S + G I C C PGYTG C +
Sbjct: 627 CFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNP 686
Query: 268 CVHGRFREEEC---SCVCDIGYGGAQCATKVH 296
C +G E+ +C C GY C ++V+
Sbjct: 687 CHNGGTCEDGINGFTCRCPEGYHDPTCLSEVN 718
Score = 35.4 bits (80), Expect = 0.11
Identities = 46/193 (23%), Positives = 62/193 (32%), Gaps = 43/193 (22%)
Query: 141 CARNATCTHYT-----------QLVWATSSQLGCGRHLCSAGQAAIE---AFVCAYSPRG 186
C ATCT Y V + C H C G ++ + C+ PRG
Sbjct: 1154 CQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCS-CPRG 1212
Query: 187 ----NWEVN----GKTIVPYKKGAWC---SLCTASVSG--CFKAWDHAGGLCEVPRNPCR 233
+ E+N + P + C C V G C G CE N C
Sbjct: 1213 TQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECL 1272
Query: 234 MS-CQNHGRLN----ISTCHCHCPPGYTGRYCQ----------VRCSLQCVHGRFREEEC 278
+ C G N ++ HC C G+TGR C+ + C
Sbjct: 1273 SNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGF 1332
Query: 279 SCVCDIGYGGAQC 291
C C G+ GA C
Sbjct: 1333 ICKCPAGFEGATC 1345
Score = 34.7 bits (78), Expect = 0.18
Identities = 43/179 (24%), Positives = 57/179 (31%), Gaps = 32/179 (17%)
Query: 131 GQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQAAIEAFVCAYSPRGNWEV 190
G+R EC N TQ + C C AG R +
Sbjct: 1261 GERCEGDVNECLSNPCDARGTQNCVQRVNDFHCE---CRAGHTG---------RRCESVI 1308
Query: 191 NGKTIVPYKKGAWCSLCTASVSG--CFKAWDHAGGLCEVPRNPC-RMSCQNHGRL----N 243
NG P K G C++ + + G C G CE C + C N G
Sbjct: 1309 NGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPR 1368
Query: 244 ISTCHCHCPPGYTGRYCQVRCSLQCVHGR--FREEECS---------CVCDIGYGGAQC 291
TC C P +TG CQ S C+ G + + C C+C + G C
Sbjct: 1369 SPTCLCLGP--FTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLC 1425
Score = 34.3 bits (77), Expect = 0.24
Identities = 27/102 (26%), Positives = 34/102 (33%), Gaps = 31/102 (30%)
Query: 214 CFKAWDHAGGLCEVPRNPCRMSCQNHGRLNISTCH-------CHCPPGYTGRYCQV---- 262
C W G C + C + HG +TCH C CP G TG C +
Sbjct: 323 CVNGW--TGEDCSENIDDCASAACFHG----ATCHDRVASFYCECPHGRTGLLCHLNDAC 376
Query: 263 ---------RCSLQCVHGRFREEECSCVCDIGYGGAQCATKV 295
C V+G+ C C GY G C+ V
Sbjct: 377 ISNPCNEGSNCDTNPVNGK-----AICTCPSGYTGPACSQDV 413
Score = 33.1 bits (74), Expect = 0.52
Identities = 30/114 (26%), Positives = 45/114 (39%), Gaps = 17/114 (14%)
Query: 197 PYKKGAWCSLCTAS-VSGCFKAWDHAGGLCEVPRNPCRMS-CQNHGRL--NISTCHCHCP 252
P G C T+ V C + + +G C+ N C + C N G +++ C+C
Sbjct: 761 PCVNGGTCKDMTSGYVCTCREGF--SGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCL 818
Query: 253 PGYTGRYCQVRCSLQCVHGRFRE----------EECSCVCDIGYGGAQCATKVH 296
YTG C+V + C R E SCVC G+ G C ++
Sbjct: 819 LPYTGATCEVVLA-PCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDIN 871
Score = 30.0 bits (66), Expect = 4.4
Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 13/59 (22%)
Query: 249 CHCPPGYTGRYCQV---RCSL---QCVH-----GRFREEECSCVCDIGYGGAQCATKVH 296
C CP GYTG C CSL C H EC C+ GY G +C V+
Sbjct: 398 CTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCL--QGYTGPRCEIDVN 454
>gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]
Length = 2416
Score = 58.2 bits (139), Expect = 2e-08
Identities = 44/187 (23%), Positives = 72/187 (38%), Gaps = 49/187 (26%)
Query: 249 CHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFHTCDLRIDG 308
C CPPGYTG +C + ++E VC+ G+ + G
Sbjct: 2188 CLCPPGYTGEHCNI------------DQE---VCEEGWN-----------------KYQG 2215
Query: 309 DCFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFETRN 368
C+ + +T+ A +C+ + L+ I + + Q+ + N D
Sbjct: 2216 HCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFV---------NNNAQDYQ----- 2261
Query: 369 FWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNH--GFGNCVELQASAAFNWNDQRCKT 426
WIGL +T + FRW+ G F ++ QPDN +CV + WND C
Sbjct: 2262 -WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNY 2320
Query: 427 RNRYICQ 433
+ C+
Sbjct: 2321 HLPFTCK 2327
>gi|156627579 C-type lectin domain family 3, member B [Homo sapiens]
Length = 202
Score = 58.2 bits (139), Expect = 2e-08
Identities = 38/128 (29%), Positives = 57/128 (44%), Gaps = 12/128 (9%)
Query: 310 CFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFETRNF 369
CF+ ++ T++ A C +GG L ++ D L YL R NE
Sbjct: 81 CFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYL-RQSVGNEA--------EI 131
Query: 370 WIGLTYKTAKDSFRWATGEHQAFTSFAF---GQPDNHGFGNCVELQASAAFNWNDQRCKT 426
W+GL A+ ++ TG A+ ++ QPD NC L +A W D+RC+
Sbjct: 132 WLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRD 191
Query: 427 RNRYICQF 434
+ YICQF
Sbjct: 192 QLPYICQF 199
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.135 0.462
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,728,416
Number of Sequences: 37866
Number of extensions: 930069
Number of successful extensions: 4123
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 114
Number of HSP's successfully gapped in prelim test: 190
Number of HSP's that attempted gapping in prelim test: 2605
Number of HSP's gapped (non-prelim): 1086
length of query: 446
length of database: 18,247,518
effective HSP length: 105
effective length of query: 341
effective length of database: 14,271,588
effective search space: 4866611508
effective search space used: 4866611508
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.