Guide to the Human Genome
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Name: ACAN Sequence: fasta or formatted (2416aa) NCBI GI: 126090892
Description:

aggrecan isoform 2 precursor

Referenced in:

Bone and Related Tissues
Protein Glycosylation
Extracellular Matrix

Other entries for this name:
alt prot [2317aa] aggrecan isoform 1 precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.9        166           3
 C cysteine            1.4         34           1
 D aspartate           4.5        108           1
 E glutamate          11.0        266           3
 F phenylalanine       2.8         68           2
 G glycine            12.0        291           2
 H histidine           1.4         33           2
 I isoleucine          3.4         82           2
 K lysine              1.2         28           2
 L leucine             7.6        183           2
 M methionine          0.5         13           1
 N asparagine          1.2         30           3
 P proline             9.1        219           2
 Q glutamine           2.6         63           2
 R arginine            3.3         79           2
 S serine             12.3        297           3
 T threonine           8.2        198           3
 V valine              7.6        184           3
 W tryptophan          1.0         25           1
 Y tyrosine            2.0         49           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   aggrecan isoform 2 precursor 
ACAN                  0.940   aggrecan isoform 1 precursor 
BCAN                  0.071   brevican isoform 2 
BCAN                  0.071   brevican isoform 1 
VCAN                  0.070   versican isoform 1 
VCAN                  0.070   versican isoform 2 
NCAN                  0.063   chondroitin sulfate proteoglycan 3 
HAPLN3                0.041   hyaluronan and proteoglycan link protein 3 
HAPLN1                0.039   hyaluronan and proteoglycan link protein 1 
HAPLN2                0.034   brain link protein-1 
HAPLN4                0.034   hyaluronan and proteoglycan link protein 4 
COL3A1                0.026   collagen type III alpha 1 preproprotein 
COL4A1                0.024   alpha 1 type IV collagen preproprotein 
COL4A6                0.024   type IV alpha 6 collagen isoform A precursor 
COL4A6                0.024   type IV alpha 6 collagen isoform B precursor 
COL5A2                0.022   alpha 2 type V collagen preproprotein 
MUC4                  0.021   mucin 4 isoform a 
COL4A5                0.021   type IV collagen alpha 5 isoform 1 precursor 
COL4A5                0.021   type IV collagen alpha 5 isoform 2 precursor 
COL4A5                0.021   type IV collagen alpha 5 isoform 3 precursor 
COL4A3                0.021   alpha 3 type IV collagen isoform 5 precursor 
COL4A3                0.021   alpha 3 type IV collagen isoform 4 precursor 
COL4A3                0.021   alpha 3 type IV collagen isoform 2 precursor 
COL4A3                0.021   alpha 3 type IV collagen isoform 1 precursor 
COL5A3                0.020   collagen, type V, alpha 3 preproprotein 
MUC12                 0.019   PREDICTED: mucin 12 
MUC12                 0.019   PREDICTED: mucin 12 
COL4A2                0.019   alpha 2 type IV collagen preproprotein 
MRC2                  0.019   mannose receptor, C type 2 
COL24A1               0.019   collagen, type XXIV, alpha 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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