Search of human proteins with 192449445

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|192449445 cartilage intermediate layer protein [Homo
sapiens]
         (1184 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|192449445 cartilage intermediate layer protein [Homo sapiens]     2440   0.0  
gi|145699139 cartilage intermediate layer protein 2 [Homo sapiens]   1188   0.0  
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]     57   1e-07
gi|239755460 PREDICTED: similar to mucin, partial [Homo sapiens]       54   1e-06
gi|161019170 mucin 5AC [Homo sapiens]                                  53   2e-06
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       53   2e-06
gi|147904700 semaphorin 5A [Homo sapiens]                              52   3e-06
gi|8923894 thrombospondin type I domain-containing 1 isoform 1 [...    52   3e-06
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]         52   3e-06
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]          52   3e-06
gi|56121815 ADAM metallopeptidase with thrombospondin type 1 mot...    51   7e-06
gi|110349719 titin isoform N2-A [Homo sapiens]                         50   1e-05
gi|134031945 SCO-spondin [Homo sapiens]                                50   1e-05
gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens]    49   2e-05
gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens]      49   3e-05
gi|110825974 ADAM metallopeptidase with thrombospondin type 1 mo...    49   3e-05
gi|40317626 thrombospondin 1 precursor [Homo sapiens]                  48   6e-05
gi|19882241 immunoglobulin superfamily, DCC subclass, member 4 [...    48   6e-05
gi|126517478 peroxidasin homolog-like [Homo sapiens]                   48   6e-05
gi|109150416 peroxidasin [Homo sapiens]                                47   1e-04
gi|164698517 MAM domain containing 1 isoform 1 [Homo sapiens]          47   1e-04
gi|11321597 kinase insert domain receptor precursor [Homo sapiens]     46   2e-04
gi|54607118 leucine-rich repeats and immunoglobulin-like domains...    46   2e-04
gi|27886566 mucosa associated lymphoid tissue lymphoma transloca...    46   2e-04
gi|5803078 mucosa associated lymphoid tissue lymphoma translocat...    46   2e-04
gi|110347423 spondin 1, extracellular matrix protein [Homo sapiens]    46   2e-04
gi|110349717 titin isoform novex-2 [Homo sapiens]                      45   3e-04
gi|110349713 titin isoform novex-1 [Homo sapiens]                      45   3e-04
gi|110349715 titin isoform N2-B [Homo sapiens]                         45   3e-04
gi|118572606 hemicentin 1 [Homo sapiens]                               45   3e-04

>gi|192449445 cartilage intermediate layer protein [Homo sapiens]
          Length = 1184

 Score = 2441 bits (6325), Expect = 0.0
 Identities = 1184/1184 (100%), Positives = 1184/1184 (100%)

Query: 1    MVGTKAWVFSFLVLEVTSVLGRQTMLTQSVRRVQPGKKNPSIFAKPADTLESPGEWTTWF 60
            MVGTKAWVFSFLVLEVTSVLGRQTMLTQSVRRVQPGKKNPSIFAKPADTLESPGEWTTWF
Sbjct: 1    MVGTKAWVFSFLVLEVTSVLGRQTMLTQSVRRVQPGKKNPSIFAKPADTLESPGEWTTWF 60

Query: 61   NIDYPGGKGDYERLDAIRFYYGDRVCARPLRLEARTTDWTPAGSTGQVVHGSPREGFWCL 120
            NIDYPGGKGDYERLDAIRFYYGDRVCARPLRLEARTTDWTPAGSTGQVVHGSPREGFWCL
Sbjct: 61   NIDYPGGKGDYERLDAIRFYYGDRVCARPLRLEARTTDWTPAGSTGQVVHGSPREGFWCL 120

Query: 121  NREQRPGQNCSNYTVRFLCPPGSLRRDTERIWSPWSPWSKCSAACGQTGVQTRTRICLAE 180
            NREQRPGQNCSNYTVRFLCPPGSLRRDTERIWSPWSPWSKCSAACGQTGVQTRTRICLAE
Sbjct: 121  NREQRPGQNCSNYTVRFLCPPGSLRRDTERIWSPWSPWSKCSAACGQTGVQTRTRICLAE 180

Query: 181  MVSLCSEASEEGQHCMGQDCTACDLTCPMGQVNADCDACMCQDFMLHGAVSLPGGAPASG 240
            MVSLCSEASEEGQHCMGQDCTACDLTCPMGQVNADCDACMCQDFMLHGAVSLPGGAPASG
Sbjct: 181  MVSLCSEASEEGQHCMGQDCTACDLTCPMGQVNADCDACMCQDFMLHGAVSLPGGAPASG 240

Query: 241  AAIYLLTKTPKLLTQTDSDGRFRIPGLCPDGKSILKITKVKFAPIVLTMPKTSLKAATIK 300
            AAIYLLTKTPKLLTQTDSDGRFRIPGLCPDGKSILKITKVKFAPIVLTMPKTSLKAATIK
Sbjct: 241  AAIYLLTKTPKLLTQTDSDGRFRIPGLCPDGKSILKITKVKFAPIVLTMPKTSLKAATIK 300

Query: 301  AEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHESK 360
            AEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHESK
Sbjct: 301  AEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHESK 360

Query: 361  LVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPVPESYLIRLPHDCFQN 420
            LVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPVPESYLIRLPHDCFQN
Sbjct: 361  LVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPVPESYLIRLPHDCFQN 420

Query: 421  ATNSFYYDVGRCPVKTCAGQQDNGIRCRDAVQNCCGISKTEEREIQCSGYTLPTKVAKEC 480
            ATNSFYYDVGRCPVKTCAGQQDNGIRCRDAVQNCCGISKTEEREIQCSGYTLPTKVAKEC
Sbjct: 421  ATNSFYYDVGRCPVKTCAGQQDNGIRCRDAVQNCCGISKTEEREIQCSGYTLPTKVAKEC 480

Query: 481  SCQRCTETRSIVRGRVSAADNGEPMRFGHVYMGNSRVSMTGYKGTFTLHVPQDTERLVLT 540
            SCQRCTETRSIVRGRVSAADNGEPMRFGHVYMGNSRVSMTGYKGTFTLHVPQDTERLVLT
Sbjct: 481  SCQRCTETRSIVRGRVSAADNGEPMRFGHVYMGNSRVSMTGYKGTFTLHVPQDTERLVLT 540

Query: 541  FVDRLQKFVNTTKVLPFNKKGSAVFHEIKMLRRKEPITLEAMETNIIPLGEVVGEDPMAE 600
            FVDRLQKFVNTTKVLPFNKKGSAVFHEIKMLRRKEPITLEAMETNIIPLGEVVGEDPMAE
Sbjct: 541  FVDRLQKFVNTTKVLPFNKKGSAVFHEIKMLRRKEPITLEAMETNIIPLGEVVGEDPMAE 600

Query: 601  LEIPSRSFYRQNGEPYIGKVKASVTFLDPRNISTATAAQTDLNFINDEGDTFPLRTYGMF 660
            LEIPSRSFYRQNGEPYIGKVKASVTFLDPRNISTATAAQTDLNFINDEGDTFPLRTYGMF
Sbjct: 601  LEIPSRSFYRQNGEPYIGKVKASVTFLDPRNISTATAAQTDLNFINDEGDTFPLRTYGMF 660

Query: 661  SVDFRDEVTSEPLNAGKVKVHLDSTQVKMPEHISTVKLWSLNPDTGLWEEEGDFKFENQR 720
            SVDFRDEVTSEPLNAGKVKVHLDSTQVKMPEHISTVKLWSLNPDTGLWEEEGDFKFENQR
Sbjct: 661  SVDFRDEVTSEPLNAGKVKVHLDSTQVKMPEHISTVKLWSLNPDTGLWEEEGDFKFENQR 720

Query: 721  RNKREDRTFLVGNLEIRERRLFNLDVPESRRCFVKVRAYRSERFLPSEQIQGVVISVINL 780
            RNKREDRTFLVGNLEIRERRLFNLDVPESRRCFVKVRAYRSERFLPSEQIQGVVISVINL
Sbjct: 721  RNKREDRTFLVGNLEIRERRLFNLDVPESRRCFVKVRAYRSERFLPSEQIQGVVISVINL 780

Query: 781  EPRTGFLSNPRAWGRFDSVITGPNGACVPAFCDDQSPDAYSAYVLASLAGEELQAVESSP 840
            EPRTGFLSNPRAWGRFDSVITGPNGACVPAFCDDQSPDAYSAYVLASLAGEELQAVESSP
Sbjct: 781  EPRTGFLSNPRAWGRFDSVITGPNGACVPAFCDDQSPDAYSAYVLASLAGEELQAVESSP 840

Query: 841  KFNPNAIGVPQPYLNKLNYRRTDHEDPRVKKTAFQISMAKPRPNSAEESNGPIYAFENLR 900
            KFNPNAIGVPQPYLNKLNYRRTDHEDPRVKKTAFQISMAKPRPNSAEESNGPIYAFENLR
Sbjct: 841  KFNPNAIGVPQPYLNKLNYRRTDHEDPRVKKTAFQISMAKPRPNSAEESNGPIYAFENLR 900

Query: 901  ACEEAPPSAAHFRFYQIEGDRYDYNTVPFNEDDPMSWTEDYLAWWPKPMEFRACYIKVKI 960
            ACEEAPPSAAHFRFYQIEGDRYDYNTVPFNEDDPMSWTEDYLAWWPKPMEFRACYIKVKI
Sbjct: 901  ACEEAPPSAAHFRFYQIEGDRYDYNTVPFNEDDPMSWTEDYLAWWPKPMEFRACYIKVKI 960

Query: 961  VGPLEVNVRSRNMGGTHRQTVGKLYGIRDVRSTRDRDQPNVSAACLEFKCSGMLYDQDRV 1020
            VGPLEVNVRSRNMGGTHRQTVGKLYGIRDVRSTRDRDQPNVSAACLEFKCSGMLYDQDRV
Sbjct: 961  VGPLEVNVRSRNMGGTHRQTVGKLYGIRDVRSTRDRDQPNVSAACLEFKCSGMLYDQDRV 1020

Query: 1021 DRTLVKVIPQGSCRRASVNPMLHEYLVNHLPLAVNNDTSEYTMLAPLDPLGHNYGIYTVT 1080
            DRTLVKVIPQGSCRRASVNPMLHEYLVNHLPLAVNNDTSEYTMLAPLDPLGHNYGIYTVT
Sbjct: 1021 DRTLVKVIPQGSCRRASVNPMLHEYLVNHLPLAVNNDTSEYTMLAPLDPLGHNYGIYTVT 1080

Query: 1081 DQDPRTAKEIALGRCFDGTSDGSSRIMKSNVGVALTFNCVERQVGRQSAFQYLQSTPAQS 1140
            DQDPRTAKEIALGRCFDGTSDGSSRIMKSNVGVALTFNCVERQVGRQSAFQYLQSTPAQS
Sbjct: 1081 DQDPRTAKEIALGRCFDGTSDGSSRIMKSNVGVALTFNCVERQVGRQSAFQYLQSTPAQS 1140

Query: 1141 PAAGTVQGRVPSRRQQRASRGGQRQGGVVASLRFPRVAQQPLIN 1184
            PAAGTVQGRVPSRRQQRASRGGQRQGGVVASLRFPRVAQQPLIN
Sbjct: 1141 PAAGTVQGRVPSRRQQRASRGGQRQGGVVASLRFPRVAQQPLIN 1184


>gi|145699139 cartilage intermediate layer protein 2 [Homo sapiens]
          Length = 1156

 Score = 1188 bits (3074), Expect = 0.0
 Identities = 578/1143 (50%), Positives = 756/1143 (66%), Gaps = 33/1143 (2%)

Query: 24   TMLTQSVRRVQPGKKNPSIFAKPADTLESPGEWTTWFNIDYPGGKGDYERLDAIRFYYGD 83
            T L    R V  G+ +P++     +  E   EWT+WFN+D+PGG GD+E L AIRFYYG 
Sbjct: 32   TALGLERRSVYTGQPSPAL-----EDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGP 86

Query: 84   -RVCARPLRLEARTTDWTPAGSTGQVVHGSPREGFWCLNREQRPGQNCSNYTVRFLCPPG 142
             RVC RPL LEARTTDW    + G+ VH +P  GFWCLNREQ  G+ CSNY VRF CP  
Sbjct: 87   ARVCPRPLALEARTTDWALPSAVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCP-- 144

Query: 143  SLRRDTERIWSPWSPWSKCSAACGQTGVQTRTRICLAEMVSLCSEASEEGQHCMGQDCTA 202
                  E  W  W PW  CS +CG  G + R R C +     C     E Q C+   C  
Sbjct: 145  -----LEASWGAWGPWGPCSGSCGP-GRRLRRRHCPSPAGDACPGRPLEAQKCVRPRCPG 198

Query: 203  CDLTCPMGQVNADCDACMCQDFMLHGAVSLPGGAPASGAAIYLLTKTPKLLTQTDSDGRF 262
            C L           D C C D +L G+V  P G P  GA + L  + P  +  +D+ G F
Sbjct: 199  CSL-----------DTCECPDHILLGSVVTPSGQPLLGARVSLRDQ-PGTVATSDAHGTF 246

Query: 263  RIPGLCPDGKSILKITKVKF-APIVLTMPKTSLKAATIKAEFVRAETPYMVMNPETKARR 321
            R+PG+C D ++ ++     F A         S+   TI  +  + E PY+V +PE++ R 
Sbjct: 247  RVPGVCADSRANIRAQMDGFSAGEAQAQANGSISVVTIILD--KLEKPYLVKHPESRVRE 304

Query: 322  AGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHESKLVLRKLQQHQAGEYFCKAQSD 381
            AGQ+V+ CCKA+G P P KY W+HN TLLD   + + + L LR L+  QAG Y CKA ++
Sbjct: 305  AGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRAHGYGAHLELRGLRPDQAGIYHCKAWNE 364

Query: 382  AGAVKSKVAQLIVIASDETPCNPVPESYLIRLPHDCFQNATNSFYYDVGRCPVKTCAGQQ 441
            AGAV+S  A+L V+A  +  C+P P  YLI+LP DC Q  +   Y DVG CP   C    
Sbjct: 365  AGAVRSGTARLTVLAPGQPACDPRPREYLIKLPEDCGQPGSGPAYLDVGLCPDTRCPSLA 424

Query: 442  DNGIRCRDAVQNCCGISKTEEREIQCSGYTLPTKVAKECSCQRCTETRSIVRGRVSAADN 501
             +  RC DA   CC + + E REI C GY LP KV  EC CQ+C   R +VRGRV AAD+
Sbjct: 425  GSSPRCGDASSRCCSVRRLERREIHCPGYVLPVKVVAECGCQKCLPPRGLVRGRVVAADS 484

Query: 502  GEPMRFGHVYMGNSRVSMTGYKGTFTLHVPQDTERLVLTFVDRLQKFVNTTKVLPFNKKG 561
            GEP+RF  + +G   +  T Y+G FT+ VP  T+RLV+TFVD   +F++  +VLPF+ +G
Sbjct: 485  GEPLRFARILLGQEPIGFTAYQGDFTIEVPPSTQRLVVTFVDPSGEFMDAVRVLPFDPRG 544

Query: 562  SAVFHEIKMLRRKEPITLEAMETNIIPLGEVVGEDPMAELEIPSRSFYRQNGEPYIGKVK 621
            + V+HE+K +R+K P+ L   ++N IPLGE+  E P+ EL +PS +F R +G+PY G V+
Sbjct: 545  AGVYHEVKAMRKKAPVILHTSQSNTIPLGELEDEAPLGELVLPSGAFRRADGKPYSGPVE 604

Query: 622  ASVTFLDPRNISTATAAQTDLNFINDEGDTFPLRTYGMFSVDFRDEVTSEPLNAGKVKVH 681
            A VTF+DPR++++A +A +DL F++ +G+  PLRTYGMFSVD R   ++E L  G V V 
Sbjct: 605  ARVTFVDPRDLTSAASAPSDLRFVDSDGELAPLRTYGMFSVDLRAPGSAEQLQVGPVAVR 664

Query: 682  LDSTQVKMPEHISTVKLWSLNPDTGLWEEEGDFKFENQR--RNKREDRTFLVGNLEIRER 739
            + ++Q+ MP H+  +KLWSLNP+TGLWEEE  F+ E     R +RE+R FLVGN+EIRER
Sbjct: 665  VAASQIHMPGHVEALKLWSLNPETGLWEEESGFRREGSSGPRVRREERVFLVGNVEIRER 724

Query: 740  RLFNLDVPESRRCFVKVRAYRSERFLPSEQIQGVVISVINLEPRTGFLSNPRAWGRFDSV 799
            RLFNLDVPE RRCFVKVRAY +++F PSEQ++GVV++++NLEP  GF +NPRAWGRFDS 
Sbjct: 725  RLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSA 784

Query: 800  ITGPNGACVPAFCDDQSPDAYSAYVLASLAGEELQAVESSPKFNPNAIGVPQPYLNKLNY 859
            +TGPNGAC+PAFCD   PDAY+A V A+L GEEL+   S P+  P  +GV QPYL++L Y
Sbjct: 785  VTGPNGACLPAFCDADRPDAYTALVTATLGGEELEPAPSLPRPLPATVGVTQPYLDRLGY 844

Query: 860  RRTDHEDPRVKKTAFQISMAKPRPNSAEESNGPIYAFENLRACEEAPPSAAHFRFYQIEG 919
            RRTDH+DP  K+  F+I++AKPRP    E+NGP+Y + +LR C+ AP +A+HFRF ++E 
Sbjct: 845  RRTDHDDPAFKRNGFRINLAKPRPGDPAEANGPVYPWRSLRECQGAPVTASHFRFARVEA 904

Query: 920  DRYDYNTVPFNEDDPMSWTEDYLAWWPKPMEFRACYIKVKIVGPLEVNVRSRNMGGTHRQ 979
            D+Y+YN VPF E  P SWT D LAWWP P EFRAC++KVKI GP E  VRS N GG+H +
Sbjct: 905  DKYEYNVVPFREGTPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNAGGSHPR 964

Query: 980  TVGKLYGIRDVRSTRDRDQPNVSAACLEFKCSGMLYDQDRVDRTLVKVIPQGSCRRASVN 1039
            T G+LYG+RD RS RD ++P  SAAC+EFKCSGML+DQ +VDRTLV ++PQGSCRR +VN
Sbjct: 965  TRGQLYGLRDARSVRDPERPGTSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVN 1024

Query: 1040 PMLHEYLVNHLPLAVNNDTSEYTMLAPLDPLGHNYGIYTVTDQDPRTAKEIALGRCFDGT 1099
             +L +YL  H P     D + ++MLAPLDPLGHNYG+YTVTDQ PR AKEIA+GRCFDG+
Sbjct: 1025 GLLRDYLTRHPPPVPAEDPAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGS 1084

Query: 1100 SDGSSRIMKSNVGVALTFNCVERQVGRQSAFQYLQSTPAQSPAAGTVQGRVPSRRQQRAS 1159
            SDG SR MK++ G A+TF C E   GR S FQ L  +PA   A G ++  +    Q +A 
Sbjct: 1085 SDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLLESPA--TALGDIRREMSEAAQAQAR 1142

Query: 1160 RGG 1162
              G
Sbjct: 1143 ASG 1145


>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
          Length = 2013

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 34/89 (38%), Positives = 45/89 (50%), Gaps = 7/89 (7%)

Query: 56   WTTWFNIDYPG---GKGDYERLDAIRFYYGDRVCARPLRLEARTTD--WTPAGSTGQVVH 110
            W+ W ++  PG     GD++ L+ +R + G RVC  P  +E R  D    P  + GQ V 
Sbjct: 1389 WSPWMDVSRPGRGTDSGDFDTLENLRAH-GYRVCESPRSVECRAEDAPGVPLRALGQRVQ 1447

Query: 111  GSPREGFWCLNREQRPGQNCSNYTVRFLC 139
             SP  G  C NREQ  G  C NY +R  C
Sbjct: 1448 CSPDVGLTCRNREQASGL-CYNYQIRVQC 1475



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 34/93 (36%), Positives = 48/93 (51%), Gaps = 10/93 (10%)

Query: 56   WTTWFNIDYPG---GKGDYERLDAIRFYYGDRVCARP-----LRLEARTTDWTPAGSTGQ 107
            WT WF++D+P      GD E  + I    G+++C RP     L+  A++         GQ
Sbjct: 1749 WTKWFDVDFPSPGPHGGDKETYNNI-IRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQ 1807

Query: 108  VVHGSPREGFWCLNREQR-PGQNCSNYTVRFLC 139
            VV  S  EG  C N++Q+ P + C NY VR LC
Sbjct: 1808 VVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLC 1840



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 30/89 (33%), Positives = 39/89 (43%), Gaps = 7/89 (7%)

Query: 56   WTTWFNIDYPG---GKGDYERLDAIRFYYGDRVCARPLRLEARTTDW--TPAGSTGQVVH 110
            WT W +  YP      GD++    +R   G   C  P  ++ R   +  TP    GQ V 
Sbjct: 1584 WTEWIDGSYPAPGINGGDFDTFQNLRDE-GYTFCESPRSVQCRAESFPNTPLADLGQDVI 1642

Query: 111  GSPREGFWCLNREQRPGQNCSNYTVRFLC 139
             S  EG  CLN+ Q P   C NY +R  C
Sbjct: 1643 CSHTEGLICLNKNQLP-PICYNYEIRIQC 1670


>gi|239755460 PREDICTED: similar to mucin, partial [Homo sapiens]
          Length = 1064

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 35/93 (37%), Positives = 47/93 (50%), Gaps = 10/93 (10%)

Query: 56  WTTWFNIDYPG---GKGDYERLDAIRFYYGDRVCARP---LRLEARTTDWTPAG--STGQ 107
           WT WF++D+P      GD E  + I    G+++C RP    RL+ R            GQ
Sbjct: 107 WTKWFDVDFPSPGPHGGDKETYNNI-IRSGEKICRRPEEITRLQCRAESHPEVNIEHLGQ 165

Query: 108 VVHGSPREGFWCLNREQR-PGQNCSNYTVRFLC 139
           VV  S  EG  C N++Q+ P + C NY VR LC
Sbjct: 166 VVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLC 198


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 7/91 (7%)

Query: 55   EWTTWFNIDYPG---GKGDYERLDAIRFYYGDRVCARPLRLEARTTDWTPAG--STGQVV 109
            EWT WF++D+P      GD E  + IR   G ++C  P  +E R  ++        GQV+
Sbjct: 2482 EWTEWFDVDFPTSGVAGGDMETFENIR-AAGGKMCWAPKSIECRAENYPEVSIDQVGQVL 2540

Query: 110  HGSPREGFWCLNREQRPGQN-CSNYTVRFLC 139
              S   G  C N +Q    N C NY VR LC
Sbjct: 2541 TCSLETGLTCKNEDQTGRFNMCFNYNVRVLC 2571



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 42/129 (32%), Positives = 57/129 (44%), Gaps = 11/129 (8%)

Query: 18   SVLGRQTMLTQSVRRVQPGKKNPSIFAKPADTLESPGEWTTWFNIDYPGGK---GDYERL 74
            S+     + +Q+     P    PS  A    T +   +WT WF+ DYP  +   GD E  
Sbjct: 2166 SIRSTAALTSQTGSSSGPVTVTPS--APGTTTCQPRCQWTEWFDEDYPKSEQLGGDVESY 2223

Query: 75   DAIRFYYGDRVCARPLRLEART---TDWTPAGSTGQVVHGSPREGFWCLNREQR-PGQNC 130
            D IR   G  +C +P  +E +     +WT A   GQ VH     G  C N EQ    + C
Sbjct: 2224 DKIR-AAGGHLCQQPKDIECQAESFPNWTLA-QVGQKVHCDVHFGLVCRNWEQEGVFKMC 2281

Query: 131  SNYTVRFLC 139
             NY +R LC
Sbjct: 2282 YNYRIRVLC 2290



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 43/140 (30%), Positives = 57/140 (40%), Gaps = 18/140 (12%)

Query: 17   TSVLGRQTMLTQSVRRVQPGKKNPSIF------AKPADTLESPG-----EWTTWFNIDYP 65
            T+  G  T  +++     P K   S        + P  T+ + G      W+ W +  YP
Sbjct: 4557 TTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYP 4616

Query: 66   ---GGKGDYERLDAIRFYYGDRVCARPLRLEARTT--DWTPAGSTGQVVHGSPREGFWCL 120
                  GD++    IR   G  VC +PL LE R       P G  GQVV  S   G  C 
Sbjct: 4617 MPGPSGGDFDTYSNIRAA-GGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCR 4675

Query: 121  NREQ-RPGQNCSNYTVRFLC 139
            NREQ    + C NY +R  C
Sbjct: 4676 NREQVGKFKMCFNYEIRVFC 4695



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 42/140 (30%), Positives = 56/140 (40%), Gaps = 18/140 (12%)

Query: 17   TSVLGRQTMLTQSVRRVQPGKKNPSIF------AKPADTLESPG-----EWTTWFNIDYP 65
            T+  G  T  +++     P K   S        + P  T+ + G      W+ W +  YP
Sbjct: 2908 TTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYP 2967

Query: 66   ---GGKGDYERLDAIRFYYGDRVCARPLRLEARTT--DWTPAGSTGQVVHGSPREGFWCL 120
                  GD++    IR   G  VC +PL LE R       P    GQVV  S   G  C 
Sbjct: 2968 MPGPSGGDFDTYSNIRAA-GGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCR 3026

Query: 121  NREQ-RPGQNCSNYTVRFLC 139
            NREQ    + C NY +R  C
Sbjct: 3027 NREQVGKFKMCFNYEIRVFC 3046



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 33/90 (36%), Positives = 40/90 (44%), Gaps = 7/90 (7%)

Query: 56   WTTWFNIDYP---GGKGDYERLDAIRFYYGDRVCARPLRLEARTT--DWTPAGSTGQVVH 110
            W+ W +  YP      GD++    IR   G  VC +PL LE R       P    GQVV 
Sbjct: 3460 WSEWLDYSYPMPGPSGGDFDTYSNIRAA-GGAVCEQPLGLECRAQAQPGVPLRELGQVVE 3518

Query: 111  GSPREGFWCLNREQ-RPGQNCSNYTVRFLC 139
             S   G  C NREQ    + C NY +R  C
Sbjct: 3519 CSLDFGLVCRNREQVGKFKMCFNYEIRVFC 3548



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 33/90 (36%), Positives = 40/90 (44%), Gaps = 7/90 (7%)

Query: 56   WTTWFNIDYP---GGKGDYERLDAIRFYYGDRVCARPLRLEARTT--DWTPAGSTGQVVH 110
            W+ W +  YP      GD++    IR   G  VC +PL LE R       P    GQVV 
Sbjct: 4105 WSEWLDYSYPMPGPSGGDFDTYSNIRAA-GGAVCEQPLGLECRAQAQPGVPLRELGQVVE 4163

Query: 111  GSPREGFWCLNREQ-RPGQNCSNYTVRFLC 139
             S   G  C NREQ    + C NY +R  C
Sbjct: 4164 CSLDFGLVCRNREQVGKFKMCFNYEIRVFC 4193


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 7/91 (7%)

Query: 55   EWTTWFNIDYPG---GKGDYERLDAIRFYYGDRVCARPLRLEARTTDWTPAG--STGQVV 109
            EWT WF++D+P      GD E  + IR   G ++C  P  +E R  ++        GQV+
Sbjct: 1792 EWTEWFDVDFPTSGVAGGDMETFENIR-AAGGKMCWAPKSIECRAENYPEVSIDQVGQVL 1850

Query: 110  HGSPREGFWCLNREQRPGQN-CSNYTVRFLC 139
              S   G  C N +Q    N C NY VR LC
Sbjct: 1851 TCSLETGLTCKNEDQTGRFNMCFNYNVRVLC 1881



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 42/129 (32%), Positives = 57/129 (44%), Gaps = 11/129 (8%)

Query: 18   SVLGRQTMLTQSVRRVQPGKKNPSIFAKPADTLESPGEWTTWFNIDYPGGK---GDYERL 74
            S+     + +Q+     P    PS  A    T +   +WT WF+ DYP  +   GD E  
Sbjct: 1476 SIRSTAALTSQTGSSSGPVTVTPS--APGTTTCQPRCQWTEWFDEDYPKSEQLGGDVESY 1533

Query: 75   DAIRFYYGDRVCARPLRLEART---TDWTPAGSTGQVVHGSPREGFWCLNREQR-PGQNC 130
            D IR   G  +C +P  +E +     +WT A   GQ VH     G  C N EQ    + C
Sbjct: 1534 DKIR-AAGGHLCQQPKDIECQAESFPNWTLA-QVGQKVHCDVHFGLVCRNWEQEGVFKMC 1591

Query: 131  SNYTVRFLC 139
             NY +R LC
Sbjct: 1592 YNYRIRVLC 1600



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 43/140 (30%), Positives = 57/140 (40%), Gaps = 18/140 (12%)

Query: 17   TSVLGRQTMLTQSVRRVQPGKKNPSIF------AKPADTLESPG-----EWTTWFNIDYP 65
            T+  G  T  +++     P K   S        + P  T+ + G      W+ W +  YP
Sbjct: 4087 TTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYP 4146

Query: 66   ---GGKGDYERLDAIRFYYGDRVCARPLRLEARTT--DWTPAGSTGQVVHGSPREGFWCL 120
                  GD++    IR   G  VC +PL LE R       P G  GQVV  S   G  C 
Sbjct: 4147 MPGPSGGDFDTYSNIRAA-GGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCR 4205

Query: 121  NREQ-RPGQNCSNYTVRFLC 139
            NREQ    + C NY +R  C
Sbjct: 4206 NREQVGKFKMCFNYEIRVFC 4225



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 42/140 (30%), Positives = 56/140 (40%), Gaps = 18/140 (12%)

Query: 17   TSVLGRQTMLTQSVRRVQPGKKNPSIF------AKPADTLESPG-----EWTTWFNIDYP 65
            T+  G  T  +++     P K   S        + P  T+ + G      W+ W +  YP
Sbjct: 2273 TTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYP 2332

Query: 66   ---GGKGDYERLDAIRFYYGDRVCARPLRLEARTT--DWTPAGSTGQVVHGSPREGFWCL 120
                  GD++    IR   G  VC +PL LE R       P    GQVV  S   G  C 
Sbjct: 2333 MPGPSGGDFDTYSNIRAA-GGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCR 2391

Query: 121  NREQ-RPGQNCSNYTVRFLC 139
            NREQ    + C NY +R  C
Sbjct: 2392 NREQVGKFKMCFNYEIRVFC 2411



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 33/90 (36%), Positives = 40/90 (44%), Gaps = 7/90 (7%)

Query: 56   WTTWFNIDYP---GGKGDYERLDAIRFYYGDRVCARPLRLEARTT--DWTPAGSTGQVVH 110
            W+ W +  YP      GD++    IR   G  VC +PL LE R       P    GQVV 
Sbjct: 2880 WSEWLDYSYPMPGPSGGDFDTYSNIRAA-GGAVCEQPLGLECRAQAQPGVPLRELGQVVE 2938

Query: 111  GSPREGFWCLNREQ-RPGQNCSNYTVRFLC 139
             S   G  C NREQ    + C NY +R  C
Sbjct: 2939 CSLDFGLVCRNREQVGKFKMCFNYEIRVFC 2968



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 33/90 (36%), Positives = 40/90 (44%), Gaps = 7/90 (7%)

Query: 56   WTTWFNIDYP---GGKGDYERLDAIRFYYGDRVCARPLRLEARTT--DWTPAGSTGQVVH 110
            W+ W +  YP      GD++    IR   G  VC +PL LE R       P    GQVV 
Sbjct: 3580 WSEWLDYSYPMPGPSGGDFDTYSNIRAA-GGAVCEQPLGLECRAQAQPGVPLRELGQVVE 3638

Query: 111  GSPREGFWCLNREQ-RPGQNCSNYTVRFLC 139
             S   G  C NREQ    + C NY +R  C
Sbjct: 3639 CSLDFGLVCRNREQVGKFKMCFNYEIRVFC 3668


>gi|147904700 semaphorin 5A [Homo sapiens]
          Length = 1074

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 35/121 (28%), Positives = 50/121 (41%), Gaps = 22/121 (18%)

Query: 97  TDWTPAGSTGQV---------VHGSPREGFWCLNREQRPGQNCSNYTVRFLCPPGSLRRD 147
           T W+P  +T  +          + +PR G      + R  + C+ +    LCPP      
Sbjct: 602 TSWSPCSTTCGIGFQVRQRSCSNPTPRHGGRVCVGQNREERYCNEH---LLCPP------ 652

Query: 148 TERIWSPWSPWSKCSAACGQTGVQTRTRICLAEMVSLCSEASEEGQHCMGQDCTACDLTC 207
               W+ W PW +C+A CG  G+Q R RIC  E    C+  + E Q C    C     T 
Sbjct: 653 -HMFWTGWGPWERCTAQCG-GGIQARRRIC--ENGPDCAGCNVEYQSCNTNPCPELKKTT 708

Query: 208 P 208
           P
Sbjct: 709 P 709



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 17/27 (62%), Positives = 19/27 (70%), Gaps = 1/27 (3%)

Query: 151 IWSPWSPWSKCSAACGQTGVQTRTRIC 177
           +WS WSPW+KCSA CG  G   RTR C
Sbjct: 843 VWSCWSPWTKCSATCG-GGHYMRTRSC 868



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 57/224 (25%), Positives = 79/224 (35%), Gaps = 44/224 (19%)

Query: 46  PADTLESPGEWTTWFNIDYPGGKGDYERLDAIRFYYGDRV-CARPLRLEARTTDWTPAGS 104
           P   L+    WT W  ++     G YE+    RF Y  +   A P  LE           
Sbjct: 700 PCPELKKTTPWTPWTPVNISDNGGHYEQ----RFRYTCKARLADPNLLEV---------- 745

Query: 105 TGQVVHGSPREGFWCLNREQRPGQNCSNYTVRFLCPPGSLRRDTERIWSPWSPWSKCSAA 164
                 G  R      + +   G +    +  FL             WS W+ WS+CS  
Sbjct: 746 ------GRQRIEMRYCSSDGTSGCSTDGLSGDFLRAGRYSAHTVNGAWSAWTSWSQCSRD 799

Query: 165 CGQTGVQTRTRICLAEMVSLCSEASEEGQHCMG-----QDCTACDLTCPMGQVNA----- 214
           C + G++ R R+C         E    G  C+G     Q+C    L CP+  V +     
Sbjct: 800 CSR-GIRNRKRVCNN------PEPKYGGMPCLGPSLEYQECNI--LPCPVDGVWSCWSPW 850

Query: 215 -DCDA-CMCQDFMLHGAVSLPGGAPASGAAIYLLTKTPKLLTQT 256
             C A C    +M   + S P  APA G  I L   T + L  T
Sbjct: 851 TKCSATCGGGHYMRTRSCSNP--APAYGGDICLGLHTEEALCNT 892



 Score = 38.9 bits (89), Expect = 0.029
 Identities = 21/47 (44%), Positives = 26/47 (55%), Gaps = 6/47 (12%)

Query: 152 WSPWSPWSKCSAACGQTGVQTRTRIC--LAEMVSLCSEASEEGQHCM 196
           WS WS WS+C A    +GVQ R R C  L  M S CS  + E + C+
Sbjct: 899 WSEWSDWSECEA----SGVQVRARQCILLFPMGSQCSGNTTESRPCV 941



 Score = 38.5 bits (88), Expect = 0.038
 Identities = 28/84 (33%), Positives = 33/84 (39%), Gaps = 15/84 (17%)

Query: 99  WTPAGSTGQVVHGSPREGFWCLNREQR---PGQNCSNYTVRFLCPPGSLRRDTERI--WS 153
           WTP   T     GS      CL R +    P   C  +       PG    +  R   W+
Sbjct: 549 WTPCTHTDGSAVGS------CLCRTRSCDSPAPQCGGWQCE---GPGMEIANCSRNGGWT 599

Query: 154 PWSPWSKCSAACGQTGVQTRTRIC 177
           PW+ WS CS  CG  G Q R R C
Sbjct: 600 PWTSWSPCSTTCG-IGFQVRQRSC 622


>gi|8923894 thrombospondin type I domain-containing 1 isoform 1
           [Homo sapiens]
          Length = 852

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 27/67 (40%), Positives = 37/67 (55%), Gaps = 4/67 (5%)

Query: 144 LRRDTERIWSPWSPWSKCSAACGQTGVQTRTRICLAEMVS--LCSEASEEGQHCMGQDCT 201
           ++R+TE  W  W PWS+CSA CG  GV+ R R+CL    S  +C   S E   C  ++C 
Sbjct: 336 IQRNTET-WGLWQPWSQCSATCGD-GVRERRRVCLTSFPSSPVCPGMSLEASLCSLEECA 393

Query: 202 ACDLTCP 208
           A   + P
Sbjct: 394 AFQPSSP 400


>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
          Length = 398

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 39/130 (30%), Positives = 60/130 (46%), Gaps = 13/130 (10%)

Query: 269 PDGKSILKITKVKF--------APIVLTMPKTSLKAATIKAEFVRAE---TPYMVMNPET 317
           P+GK+    + V F        A IV ++   SLK A  ++   R E   TP  ++ P+ 
Sbjct: 183 PNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGAD-RSTSQRIEVLYTPTAMIRPDP 241

Query: 318 KARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHESKLVLRKLQQHQAGEYFCK 377
              R GQ + L C+  G P P +Y W   +  + P     ES L+   L +  +G Y C 
Sbjct: 242 PHPREGQKLLLHCEGRGNPVPQQYLW-EKEGSVPPLKMTQESALIFPFLNKSDSGTYGCT 300

Query: 378 AQSDAGAVKS 387
           A S+ G+ K+
Sbjct: 301 ATSNMGSYKA 310


>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
          Length = 432

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 39/130 (30%), Positives = 60/130 (46%), Gaps = 13/130 (10%)

Query: 269 PDGKSILKITKVKF--------APIVLTMPKTSLKAATIKAEFVRAE---TPYMVMNPET 317
           P+GK+    + V F        A IV ++   SLK A  ++   R E   TP  ++ P+ 
Sbjct: 217 PNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGAD-RSTSQRIEVLYTPTAMIRPDP 275

Query: 318 KARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHESKLVLRKLQQHQAGEYFCK 377
              R GQ + L C+  G P P +Y W   +  + P     ES L+   L +  +G Y C 
Sbjct: 276 PHPREGQKLLLHCEGRGNPVPQQYLW-EKEGSVPPLKMTQESALIFPFLNKSDSGTYGCT 334

Query: 378 AQSDAGAVKS 387
           A S+ G+ K+
Sbjct: 335 ATSNMGSYKA 344


>gi|56121815 ADAM metallopeptidase with thrombospondin type 1 motif,
           10 preproprotein [Homo sapiens]
          Length = 1103

 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 37/139 (26%), Positives = 55/139 (39%), Gaps = 32/139 (23%)

Query: 107 QVVHGSPREGFWCLNREQR---------PGQNCSNYTV-------RFLCPPGSLRRDTER 150
           Q  +G      WCL++  R          G  C  +T+       R   P GS     + 
Sbjct: 489 QCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDG 548

Query: 151 IWSPWSPWSKCSAACGQTGVQTRTRICLAEMVSLCSEASEEGQHCMGQ-----DCTACDL 205
            W PW+PW  CS  CG  GV + +R C +   ++       G++C+G+      C   D 
Sbjct: 549 AWGPWTPWGDCSRTCG-GGVSSSSRHCDSPRPTI------GGKYCLGERRRHRSCNTDD- 600

Query: 206 TCPMGQVNADCDACMCQDF 224
            CP G  + D     C +F
Sbjct: 601 -CPPG--SQDFREVQCSEF 616


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 31/88 (35%), Positives = 40/88 (45%), Gaps = 7/88 (7%)

Query: 307  ETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPS------LYKHESK 360
            E PY V   E      G SVSL C+  G P      WY  DT L P+         + + 
Sbjct: 6077 EPPYFVTELEPLEAAVGDSVSLQCQVAGTPEIT-VSWYKGDTKLRPTPEYRTYFTNNVAT 6135

Query: 361  LVLRKLQQHQAGEYFCKAQSDAGAVKSK 388
            LV  K+  + +GEY CKA++  G   SK
Sbjct: 6136 LVFNKVNINDSGEYTCKAENSIGTASSK 6163



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 7/93 (7%)

Query: 301  AEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSL-YK--- 356
            A+ +  E PY V   E      G S SL C+  G P      WY  DT L P+  YK   
Sbjct: 7953 AQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIG-VSWYKGDTKLRPTTTYKMHF 8011

Query: 357  --HESKLVLRKLQQHQAGEYFCKAQSDAGAVKS 387
              + + LV  ++  + +GEY CKA++  G V +
Sbjct: 8012 RNNVATLVFNQVDINDSGEYICKAENSVGEVSA 8044



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 36/156 (23%), Positives = 62/156 (39%), Gaps = 9/156 (5%)

Query: 259   DGRFRIPGLCPDGKSILKITKVKFAPIVLTMPKTSLKAATIKAEFVRAETPYMVMNPETK 318
             D +F I GL    +   ++    FA     + +    A +IK +    E P +    +  
Sbjct: 30487 DKQFTIGGLLEATEYEFRV----FAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDV 30542

Query: 319   ARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHES-----KLVLRKLQQHQAGE 373
               + G++  L C+  G+P PD  ++     L+    YK  S      L +   +Q   G 
Sbjct: 30543 TTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGV 30602

Query: 374   YFCKAQSDAGAVKSKVAQLIVIASDETPCNPVPESY 409
             Y C A ++ G V++    L+       P  P+ E Y
Sbjct: 30603 YTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKY 30638



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 7/93 (7%)

Query: 307  ETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPS-LYKHESK----- 360
            E PY +   E      G+  +L CK  G P   +  WY   T L  +  YK + K     
Sbjct: 7018 EPPYFIEPLEHVEAVIGEPATLQCKVDGTPEI-RISWYKEHTKLRSAPAYKMQFKNNVAS 7076

Query: 361  LVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLI 393
            LV+ K+     GEY CKA +  GAV S    +I
Sbjct: 7077 LVINKVDHSDVGEYSCKADNSVGAVASSAVLVI 7109



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 9/89 (10%)

Query: 303  FVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKH----- 357
            FV+    ++     ++  + G +  L CK TG P P K  W+ ND  +  S  KH     
Sbjct: 4294 FVKEPATFVEKLEPSQLLKKGDATQLACKVTGTP-PIKITWFANDREIKESS-KHRMSFV 4351

Query: 358  ESKLVLRKLQQ--HQAGEYFCKAQSDAGA 384
            ES  VLR        +GEY C+AQ++AG+
Sbjct: 4352 ESTAVLRLTDVGIEDSGEYMCEAQNEAGS 4380



 Score = 38.5 bits (88), Expect = 0.038
 Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 8/91 (8%)

Query: 307  ETPYMVMNPE-TKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLL------DPSLYKHES 359
            E P  V   E +K  + G+S+ L CK +G P   K  W+ ND+ L      + S     +
Sbjct: 6362 EPPKFVKKLEASKVAKQGESIQLECKISGSPE-IKVSWFRNDSELHESWKYNMSFINSVA 6420

Query: 360  KLVLRKLQQHQAGEYFCKAQSDAGAVKSKVA 390
             L + +     +G+Y C+A +  G      A
Sbjct: 6421 LLTINEASAEDSGDYICEAHNGVGDASCSTA 6451



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 23/106 (21%), Positives = 47/106 (44%), Gaps = 7/106 (6%)

Query: 307  ETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSL---YKHESK--- 360
            E P ++   +    ++G+    C   +G+P+P K  WY  + LL       + H+ +   
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCAVISGRPQP-KISWYKEEQLLSTGFKCKFLHDGQEYT 3295

Query: 361  LVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPVP 406
            L+L +     A  Y C+A++D G   +  +  + +    +P   +P
Sbjct: 3296 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP 3341



 Score = 36.2 bits (82), Expect = 0.19
 Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 8/83 (9%)

Query: 323  GQSVSLCCKATGKPRPDKYFWYHNDTLLDPSL------YKHESKLVLRKLQQHQAGEYFC 376
            G+SV+L C  +G P P    WY  D  ++ S+          ++L++R+     +G + C
Sbjct: 957  GESVTLECHISGYPSPT-VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTC 1015

Query: 377  KAQSDAGAVKSKVAQLIVIASDE 399
             A ++AG V S    L V  S+E
Sbjct: 1016 SAVNEAGTV-STSCYLAVQVSEE 1037



 Score = 35.8 bits (81), Expect = 0.25
 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 8/106 (7%)

Query: 306   AETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHND------TLLDPSLYKHES 359
             ++ P  +  P ++    GQ+V   C+ +G+P P+   W+ N+      + +  S  ++  
Sbjct: 33131 SDAPAFISQPRSQNINEGQNVLFTCEISGEPSPE-IEWFKNNLPISISSNVSISRSRNVY 33189

Query: 360   KLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPV 405
              L +R      +G+Y  KA++  G   S  A L+V+   E P   V
Sbjct: 33190 SLEIRNASVSDSGKYTIKAKNFRGQC-SATASLMVLPLVEEPSREV 33234



 Score = 35.4 bits (80), Expect = 0.32
 Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 10/101 (9%)

Query: 297  ATIKAEFVRAETPYMVMNPE-TKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLY 355
            AT KA     E P  +  P      R GQS +  C+ TG P+  +  WY +   +  ++ 
Sbjct: 4849 ATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKI-RVSWYLDGNEIT-AIQ 4906

Query: 356  KHESKLV-------LRKLQQHQAGEYFCKAQSDAGAVKSKV 389
            KH    +       +   +   +G Y C+A++DAG     +
Sbjct: 4907 KHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSI 4947



 Score = 34.7 bits (78), Expect = 0.55
 Identities = 40/152 (26%), Positives = 61/152 (40%), Gaps = 18/152 (11%)

Query: 258 SDGRFRIPGLCPDGKSILKITKVKFAPIVLTMPKTSLKAATIKAEFVRAET--PYMVMNP 315
           SDGR ++        +I  +TK       L     S +A +     V+AET  P  V   
Sbjct: 59  SDGRAKL--------TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRL 110

Query: 316 ETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHESK------LVLRKLQQH 369
           ++   R G  V L  + TG P P   F Y +   +  SL    S+      L++ +    
Sbjct: 111 QSMTVRQGSQVRLQVRVTGIPTPVVKF-YRDGAEIQSSLDFQISQEGDLYSLLIAEAYPE 169

Query: 370 QAGEYFCKAQSDAGAVKSKVAQLIVIASDETP 401
            +G Y   A +  G   S  A+L+V   +E P
Sbjct: 170 DSGTYSVNATNSVGRATS-TAELLVQGEEEVP 200



 Score = 34.7 bits (78), Expect = 0.55
 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 10/95 (10%)

Query: 307  ETPYMVMNPE-TKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHESKLV--- 362
            E P  V   E +K  +AG S  L CK  G P   +  W+ N+  L P+  K+    +   
Sbjct: 5421 EPPKFVKKLEASKIVKAGDSSRLECKIAGSPEI-RVVWFRNEHEL-PASDKYRMTFIDSV 5478

Query: 363  ----LRKLQQHQAGEYFCKAQSDAGAVKSKVAQLI 393
                +  L    +G++ C+AQ+ AG+       ++
Sbjct: 5479 AVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIV 5513



 Score = 34.3 bits (77), Expect = 0.72
 Identities = 26/116 (22%), Positives = 52/116 (44%), Gaps = 12/116 (10%)

Query: 298  TIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKH 357
            T +++  R   P  V+ P +     GQ+     K  G+P P+  FW+H+   +  + Y H
Sbjct: 1446 TDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPET-FWFHDGQQI-VNDYTH 1503

Query: 358  E--------SKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPV 405
            +          L++       +GE+   AQ+ AG  +S ++ ++ + + E    P+
Sbjct: 1504 KVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAG--RSSISVILTVEAVEHQVKPM 1557



 Score = 33.9 bits (76), Expect = 0.94
 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 6/88 (6%)

Query: 307  ETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPS-----LYKHESKL 361
            + P +V+ PE      G++    C+ TG P+P K  WY N  L+  S      Y     L
Sbjct: 1839 QKPDIVLYPEPVRVLEGETARFRCRVTGYPQP-KVNWYLNGQLIRKSKRFRVRYDGIHYL 1897

Query: 362  VLRKLQQHQAGEYFCKAQSDAGAVKSKV 389
             +   + +  GE    A++  G ++ KV
Sbjct: 1898 DIVDCKSYDTGEVKVTAENPEGVIEHKV 1925



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 7/84 (8%)

Query: 307  ETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSL-YKHESK----- 360
            E P     P          VSL C+ +G P P +  WY +   L  S  YK  SK     
Sbjct: 5515 EPPVFSSFPPIVETLKNAEVSLECELSGTP-PFEVVWYKDKRQLRSSKKYKIASKNFHTS 5573

Query: 361  LVLRKLQQHQAGEYFCKAQSDAGA 384
            + +  +     GEY CKAQ++ G+
Sbjct: 5574 IHILNVDTSDIGEYHCKAQNEVGS 5597



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 46/194 (23%), Positives = 73/194 (37%), Gaps = 41/194 (21%)

Query: 316  ETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPS-----LYKHESKLV-LRKLQQH 369
            ET     G S  L  +  G  +P    WY N+  + P+      +K+ + ++ +RK   +
Sbjct: 8257 ETVEETEGNSFKLEGRVAGS-QPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMN 8315

Query: 370  QAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPVPESYLIRLPHDCFQNATNSFYYDV 429
             AG Y CK  +DAG+  +     IVI   + P  PV + +L                   
Sbjct: 8316 DAGLYTCKVSNDAGS--ALCTSSIVIKEPKKP--PVFDQHL------------------- 8352

Query: 430  GRCPVKTCAGQQDNGIRCRDAVQNCCGISKTEEREIQCSGYTLPTKVAKECSCQRCTETR 489
               PV    G+          VQ  C +  +E   IQ        K +  CS    + T 
Sbjct: 8353 --TPVTVSEGEY---------VQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTA 8401

Query: 490  SIVRGRVSAADNGE 503
             +    V+ AD+G+
Sbjct: 8402 VLELRDVAKADSGD 8415



 Score = 32.7 bits (73), Expect = 2.1
 Identities = 31/123 (25%), Positives = 51/123 (41%), Gaps = 8/123 (6%)

Query: 287   LTMPKTSLKAATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHN 346
             ++ P       TI AE V       V        +AG +V L     GKP P    W  +
Sbjct: 19274 ISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP-TVSWKKD 19332

Query: 347   DTLLDP------SLYKHESKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDET 400
              TLL P      ++ ++   L L  + +  +G+Y   A++ +G+ KS   +L V+     
Sbjct: 19333 GTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGS-KSATIKLKVLDKPGP 19391

Query: 401   PCN 403
             P +
Sbjct: 19392 PAS 19394



 Score = 32.0 bits (71), Expect = 3.6
 Identities = 24/91 (26%), Positives = 34/91 (37%), Gaps = 7/91 (7%)

Query: 309  PYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYK-------HESKL 361
            PY +  P  +    G SV   C+  G P+P  Y+      L     YK        E KL
Sbjct: 1082 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1141

Query: 362  VLRKLQQHQAGEYFCKAQSDAGAVKSKVAQL 392
            V+       AGEY    ++  G   +  + L
Sbjct: 1142 VISMTFADDAGEYTIVVRNKHGETSASASLL 1172



 Score = 32.0 bits (71), Expect = 3.6
 Identities = 30/123 (24%), Positives = 46/123 (37%), Gaps = 6/123 (4%)

Query: 288   TMPKTSLKAATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHND 347
             T   T  +    KA    +  P +V   +     +        KATG+PRP   +     
Sbjct: 32831 TTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGK 32890

Query: 348   TLLDPSLYK-HESK----LVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPC 402
              +     YK  E K    L + K     +G Y C  ++ AG+V S   +L + A  +T  
Sbjct: 32891 AITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSS-CKLTIKAIKDTEA 32949

Query: 403   NPV 405
               V
Sbjct: 32950 QKV 32952



 Score = 31.6 bits (70), Expect = 4.7
 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 13/95 (13%)

Query: 296  AATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPS-- 353
            A T+KA       P     P       G  V L C+ +G P P +  W  +   +  S  
Sbjct: 6451 ALTVKAP------PVFTQKPSPVGALKGSDVILQCEISGTP-PFEVVWVKDRKQVRNSKK 6503

Query: 354  ---LYKH-ESKLVLRKLQQHQAGEYFCKAQSDAGA 384
                 KH ++ L +  L+    GEY CKA ++ G+
Sbjct: 6504 FKITSKHFDTSLHILNLEASDVGEYHCKATNEVGS 6538



 Score = 31.6 bits (70), Expect = 4.7
 Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 10/99 (10%)

Query: 294  LKAATIKAEFVRAE---TPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLL 350
            L  A+  A+ + +E    P+  + P +     G+S +  C  TG   P K  W  ++  +
Sbjct: 7194 LGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTA-PIKITWAKDNREI 7252

Query: 351  DP------SLYKHESKLVLRKLQQHQAGEYFCKAQSDAG 383
             P      +L ++ + L + K+ +  AG+Y C A + AG
Sbjct: 7253 RPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAG 7291



 Score = 31.6 bits (70), Expect = 4.7
 Identities = 19/69 (27%), Positives = 32/69 (46%), Gaps = 7/69 (10%)

Query: 322  AGQSVSLCCKATGKPRPDKYFWYHNDTLLDP------SLYKHESKLVLRKLQQHQAGEYF 375
            +G SV + CK  G P P    W+H    +        +L  +   L +  L++  +G+Y 
Sbjct: 7695 SGSSVVMECKVYGSP-PISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYT 7753

Query: 376  CKAQSDAGA 384
            C A + AG+
Sbjct: 7754 CIATNMAGS 7762



 Score = 31.6 bits (70), Expect = 4.7
 Identities = 26/121 (21%), Positives = 50/121 (41%), Gaps = 6/121 (4%)

Query: 290   PKTSLKAATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTL 349
             P+ ++ A T++   V        M  +T    AG+ V L     G+P P   +++    L
Sbjct: 29720 PRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKL 29779

Query: 350   LDPSLYKHE-----SKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNP 404
              +      E     +KL +R+      GEY  + ++  G   S+  ++I++     P  P
Sbjct: 29780 RESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTT-SETIKVIILDKPGPPTGP 29838

Query: 405   V 405
             +
Sbjct: 29839 I 29839



 Score = 31.2 bits (69), Expect = 6.1
 Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 21/116 (18%)

Query: 311  MVMNPETKARRAG-------QSVSLCCKATGKPRPDKYFWYHNDTLLDPS------LYKH 357
            MV+ P     +AG       ++ +L CK  G P      WY +  LL  S       Y  
Sbjct: 5699 MVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVE-WYKDGKLLTSSQKHKFSFYNK 5757

Query: 358  ESKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPVPESYLIRL 413
             S L +  +++  AG Y  + Q++ G  KS    ++ ++        VP S+  RL
Sbjct: 5758 ISSLRILSVERQDAGTYTFQVQNNVG--KSSCTAVVDVSD-----RAVPPSFTRRL 5806



 Score = 31.2 bits (69), Expect = 6.1
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 7/84 (8%)

Query: 307  ETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDP------SLYKHESK 360
            E P     P++     G S++      G P P K  W+     L P      SL    ++
Sbjct: 6832 EPPSFEQTPDSVEVLPGMSLTFTSVIRGTP-PFKVKWFKGSRELVPGESCNISLEDFVTE 6890

Query: 361  LVLRKLQQHQAGEYFCKAQSDAGA 384
            L L ++Q  ++G+Y C   +DAG+
Sbjct: 6891 LELFEVQPLESGDYSCLVTNDAGS 6914



 Score = 31.2 bits (69), Expect = 6.1
 Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 5/93 (5%)

Query: 316   ETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLY---KHESKLVLRKLQQHQAG 372
             +T   RAG S+ L    +G+P P   +      L   ++    +  S L++ K+ ++ AG
Sbjct: 29454 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAG 29513

Query: 373   EYFCKAQSDAGAVKSKVAQLIVIASDETPCNPV 405
             +Y  +A++ +G  K     L+ +     PC  V
Sbjct: 29514 KYTIEAENQSG--KKSATVLVKVYDTPGPCPSV 29544



 Score = 30.8 bits (68), Expect = 8.0
 Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 14/88 (15%)

Query: 303  FVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPS------LYK 356
            FV+   P  +M P       G+S  L CK  G P   +  W+ N+  L  S         
Sbjct: 3739 FVKKVDPSYLMLP-------GESARLHCKLKGSP-VIQVTWFKNNKELSESNTVRMYFVN 3790

Query: 357  HESKLVLRKLQQHQAGEYFCKAQSDAGA 384
             E+ L +  ++   +G Y C+A +D G+
Sbjct: 3791 SEAILDITDVKVEDSGSYSCEAVNDVGS 3818


>gi|134031945 SCO-spondin [Homo sapiens]
          Length = 5147

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 30/84 (35%), Positives = 39/84 (46%), Gaps = 15/84 (17%)

Query: 152  WSPWSPWSKCSAACGQTGVQTRTRICLAEMVSLCSEASEEGQHCMGQDCTACDLTCPMGQ 211
            + PWSPW  CS +CG  G +TR+R C+  M +L       GQ C G      DL CP   
Sbjct: 3814 FGPWSPWGPCSRSCGGLGTRTRSRQCVLTMPTL------SGQGCRG---PRQDLECP--- 3861

Query: 212  VNADCDACMCQDFMLHGAVSLPGG 235
             + DC     +   +     LPGG
Sbjct: 3862 -SPDCPG--AEGSTVEPVTGLPGG 3882



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 27/71 (38%), Positives = 34/71 (47%), Gaps = 6/71 (8%)

Query: 151  IWSPWSPWSKCSAACGQTGVQTRTRIC--LAEMVSLCSEASEEGQHCMGQDCTACDLTCP 208
            IW  W+PWS CSA C   G+QTR R C  LA   + C     + + C  Q CTA    CP
Sbjct: 2832 IWGLWAPWSTCSAPC-DGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQPCTA---QCP 2887

Query: 209  MGQVNADCDAC 219
               +    + C
Sbjct: 2888 ENMLFRSAEQC 2898



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 34/97 (35%), Positives = 44/97 (45%), Gaps = 13/97 (13%)

Query: 128  QNCSNYTVRFLCPPGSLRRDTERIWSPWSPWSKCSAACGQTGVQTRTRICL-AEMVSLC- 185
            QNC+      +CP          +  PWS WS CSA CG  G   R R C     V+ C 
Sbjct: 4747 QNCTCVNESLVCPHQECP-----VLGPWSAWSSCSAPCG-GGTMERHRTCEGGPGVAPCQ 4800

Query: 186  SEASEEGQHCMGQDCTACDLTCPMGQVNADC-DACMC 221
            ++ +E+ Q C  Q C      CP GQV + C  +C C
Sbjct: 4801 AQDTEQRQECNLQPCP----ECPPGQVLSACATSCPC 4833



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 30/108 (27%), Positives = 39/108 (36%), Gaps = 7/108 (6%)

Query: 121  NREQRPGQNCSNYTVRFLCPPGSLRRDTERIWSPWSPWSKCSAACGQTGVQTRTRICLA- 179
            ++ Q    NCS    +  C        T   WS WS WS CS +CG  G Q+R R   + 
Sbjct: 4131 SQHQDACNNCSCQAGQLSCTAQPCPPPTHCAWSHWSAWSPCSHSCGPRGQQSRFRSSTSG 4190

Query: 180  EMVSLCSEASEEGQHCMGQDCTACDL------TCPMGQVNADCDACMC 221
                 C E   + Q C    C    L      T     +  +C  C C
Sbjct: 4191 SWAPECREEQSQSQPCPQPSCPPLCLQGTRSRTLGDSWLQGECQRCSC 4238



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 5/69 (7%)

Query: 152  WSPWSPWSKCSAACGQTGVQTRTRIC----LAEMVSLCSEASEEGQHCMGQDCTACDLTC 207
            W PW PWS CS +CG  G+++RTR C       +   C     +G+ C    C   + T 
Sbjct: 3255 WGPWGPWSHCSRSCG-GGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALPCPVTNCTA 3313

Query: 208  PMGQVNADC 216
              G   + C
Sbjct: 3314 IEGAEYSPC 3322



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 38/139 (27%), Positives = 57/139 (41%), Gaps = 30/139 (21%)

Query: 151  IWSPWSPWSKCSAACGQTGVQTRTRICLAEMVSLCSEASEEGQHCMGQDCTACDLTCPMG 210
            +WS W PW  CS +CG  G Q R+R C       C   + + + C  Q C   +  CP G
Sbjct: 3647 VWSSWGPWEDCSVSCG-GGEQLRSRRCARPP---CPGPARQSRTCSTQVCR--EAGCPAG 3700

Query: 211  QVNADCDACMCQDFMLHGAVSLPG-GAPASGAAIYLLTKTPKLLTQTDSDGRFRIPGLCP 269
            ++  +C                PG G P S A +   T+     ++   +G       CP
Sbjct: 3701 RLYRECQ---------------PGEGCPFSCAHV---TQQVGCFSEGCEEGCH-----CP 3737

Query: 270  DGKSILKITKVKFAPIVLT 288
            +G    ++  V+  P VLT
Sbjct: 3738 EGTFQHRLACVQECPCVLT 3756



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 31/99 (31%), Positives = 39/99 (39%), Gaps = 31/99 (31%)

Query: 125  RPGQNCSNYTVRFLCPPGSLRR-------DTERIWSPWSPWSKCSAACGQTGVQTRTRIC 177
            RP +NCS       C  G +         + E  WSPW+PWS+CSA+CG      R R C
Sbjct: 3159 RPCENCS-------CVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPARCH-RHRFC 3210

Query: 178  L----------------AEMVSLCSEASEEGQHCMGQDC 200
                             A    LCS    E + C+ Q C
Sbjct: 3211 ARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPCLLQGC 3249



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 40/139 (28%), Positives = 52/139 (37%), Gaps = 22/139 (15%)

Query: 140  PPGSLRRDTE----RIWSPWSPWSKCSAACGQTGVQTRTRICLAEMVSLCSEASEEGQHC 195
            P G +  DTE      W+ WS WS C  +CG  G Q RTR C A      +        C
Sbjct: 4240 PEGVICEDTECAVPEAWTLWSSWSDCPVSCG-GGNQVRTRACRA------AAPHHRSPPC 4292

Query: 196  MGQDCTACDLTCPMGQVNADCDACMCQDFMLHGAVSLPGGAPASGAAIYLLTKTPKLLTQ 255
            +G D       CP        +AC    +        PG A  SG+   L+ K       
Sbjct: 4293 LGPDTQTRQQPCP-----GLLEACSWGPWGPCSRSCGPGLASRSGSCPCLMAKADPTCNS 4347

Query: 256  T----DSDGRFRIPGLCPD 270
            T    D+ G +   G CP+
Sbjct: 4348 TFLHLDTQGCY--SGPCPE 4364



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 7/73 (9%)

Query: 152  WSPWSPWSKCSAAC----GQTGVQTRTRICLAEMVSLCSEASEEGQHCMGQDC---TACD 204
            W+PW+ WS CS +C    G  G ++R+R+C +   S C   + + + C    C   +   
Sbjct: 2775 WTPWTSWSSCSQSCLAPGGGPGWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWG 2834

Query: 205  LTCPMGQVNADCD 217
            L  P    +A CD
Sbjct: 2835 LWAPWSTCSAPCD 2847



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 6/72 (8%)

Query: 152  WSPWSPWSKCSAACGQTGVQTRTRICL----AEMVSLCSEASEEGQHCMGQDCTACDLTC 207
            W+ W  W  CS +CG  G Q+R R C+        + C  AS+E   C  Q C+     C
Sbjct: 2558 WAMWEAWGPCSVSCG-GGHQSRQRSCVDPPPKNGGAPCPGASQERAPCGLQPCSG-GTDC 2615

Query: 208  PMGQVNADCDAC 219
             +G+V    D C
Sbjct: 2616 ELGRVYVSADLC 2627



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 30/115 (26%), Positives = 39/115 (33%), Gaps = 22/115 (19%)

Query: 126  PGQNCSNYTVRFLCPPGSLRR-------DTERIWSPWSPWSKCSAACGQTGVQTRTRICL 178
            PGQ         +C  G  RR         +  WS WSPW+KC   CG   +Q   R   
Sbjct: 1879 PGQRIKADCQLCICQDGRPRRCRLNPDCAVDCGWSSWSPWAKCLGPCGSQSIQWSFRSSN 1938

Query: 179  AEMVS----LCSEASEEGQHCMGQDCTACDLTCPMGQVN--------ADCDACMC 221
                S     C     + + C  + C  C+     GQV+          C  C C
Sbjct: 1939 NPRPSGRGRQCRGIHRKARRCQTEPCEGCE---HQGQVHRVGERWHGGPCRVCQC 1990



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 29/97 (29%), Positives = 38/97 (39%), Gaps = 16/97 (16%)

Query: 99   WTPAGSTGQVVHG---SPREGFWCLNREQRPGQNCSNYTVRFLCP----PGSLRRDTERI 151
            W+P G   +   G     R     L      GQ C        CP    PG+     E +
Sbjct: 3817 WSPWGPCSRSCGGLGTRTRSRQCVLTMPTLSGQGCRGPRQDLECPSPDCPGAEGSTVEPV 3876

Query: 152  ------WSPWSPWSKCSAAC---GQTGVQTRTRICLA 179
                  W PWS WS CS +C    +   ++RTR+CLA
Sbjct: 3877 TGLPGGWGPWSSWSPCSRSCTDPARPAWRSRTRLCLA 3913



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 27/97 (27%), Positives = 34/97 (35%), Gaps = 14/97 (14%)

Query: 152  WSPWSPWSKCSAACGQTGVQTRTRICL---AEMVSLCSEASEEGQHCMGQDCTA---CDL 205
            W PWSPW  CS  CG  G Q R+R C      ++  C     + Q C    C        
Sbjct: 1697 WGPWSPWGPCSRTCGPWG-QGRSRRCSPLGLLVLQNCPGPEHQSQACFTAACPVDGEWST 1755

Query: 206  TCPMGQVNADCDACMCQDFMLHG-------AVSLPGG 235
              P    +  C   M +    H          +LPGG
Sbjct: 1756 WSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCAALPGG 1792



 Score = 39.7 bits (91), Expect = 0.017
 Identities = 30/102 (29%), Positives = 38/102 (37%), Gaps = 14/102 (13%)

Query: 152  WSPWSPWSKCSAAC-GQTGVQTRTRICLAEM---VSLCSEASEEGQHCMGQDCTACDLTC 207
            W PWS W+ CS  C GQT  ++R   C            EA E G     + C +   TC
Sbjct: 3411 WCPWSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSY-ATC 3469

Query: 208  PMGQV------NADCDACMCQDFMLHGAVSLP---GGAPASG 240
            P+          + CD C+ Q          P   GG P  G
Sbjct: 3470 PVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPG 3511



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 46/192 (23%), Positives = 64/192 (33%), Gaps = 56/192 (29%)

Query: 85   VCARPLRLEARTTDWTPAGSTGQVVHGSPREGFWCLNREQRPGQNCSNYTVRFLCPPGSL 144
            +C++P R + R+     A  T Q   G+P  G       Q   + C +Y     CP    
Sbjct: 3419 MCSQPCRGQTRSRSRACACPTPQH-GGAPCTGEAGEAGAQHQREACPSYAT---CP---- 3470

Query: 145  RRDTERIWSPWSPWSKCSAACGQT-------------------GVQTRTRICLAEMVSLC 185
                +  W PW PWS C    GQ+                   G  T++R C        
Sbjct: 3471 ---VDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCT 3527

Query: 186  SEASEEGQHCMGQDC-----------------TACDLT--CPMGQVNAD--C---DACMC 221
                 +  H  GQ C                   C  T  CP+GQ++ D  C     C C
Sbjct: 3528 DCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRC 3587

Query: 222  QDFMLHGAVSLP 233
            Q     GA+ +P
Sbjct: 3588 Q--YQPGAMGIP 3597



 Score = 38.5 bits (88), Expect = 0.038
 Identities = 23/72 (31%), Positives = 29/72 (40%), Gaps = 14/72 (19%)

Query: 152  WSPWSPWSKCSAACGQTGVQTRTRICLAEMVSLCSEASEEGQHCMGQDCTA-------CD 204
            WS WSPWS C  +CG  G   R+R C +        +   G  C G+   A       C+
Sbjct: 4007 WSRWSPWSWCDRSCG-GGQSLRSRSCSS------PPSKNGGAPCAGERHQARLCNPMPCE 4059

Query: 205  LTCPMGQVNADC 216
              CP G     C
Sbjct: 4060 AGCPAGMEVVTC 4071



 Score = 38.1 bits (87), Expect = 0.050
 Identities = 30/106 (28%), Positives = 42/106 (39%), Gaps = 29/106 (27%)

Query: 119  CLNREQRPGQ---------------NCSNYTVRFLCPPGSLRRDTERI-----WSPWSPW 158
            CL R Q P Q               +C+N T    C  G +   +ER      WSPW+ W
Sbjct: 2939 CLPRSQCPCQLHGQLYASGAMARLDSCNNCT----CVSGKMACTSERCPVACGWSPWTLW 2994

Query: 159  SKCSAACGQTGVQTRTRICLAEMVSL----CSEASEEGQHCMGQDC 200
            S CS +C   G++ R R   A   +     C   + E + C  + C
Sbjct: 2995 SLCSCSC-NVGIRRRFRAGTAPPAAFGGAECQGPTMEAEFCSLRPC 3039



 Score = 35.8 bits (81), Expect = 0.25
 Identities = 24/71 (33%), Positives = 30/71 (42%), Gaps = 11/71 (15%)

Query: 138  LCP-PGSLRRDTERIWSPWSPWSKCSAACGQTGVQTRTRICLAEMVSLCSEASEE---GQ 193
            LCP PG+     +  WS W PWS C   C   G + R R    E  +LC     E    +
Sbjct: 4605 LCPDPGACPDSCQ--WSLWGPWSPCQVPC-SGGFRLRWR----EAEALCGGGCREPWAQE 4657

Query: 194  HCMGQDCTACD 204
             C G  C  C+
Sbjct: 4658 SCNGGPCPECE 4668



 Score = 33.9 bits (76), Expect = 0.94
 Identities = 19/50 (38%), Positives = 23/50 (46%), Gaps = 6/50 (12%)

Query: 129  NCSNYTVR---FLCPPGSLRRDTERIWSPWSPWSKCSAACGQTGVQTRTR 175
            NCS         LC PG         WS WS W+ C  +CG +GV+ R R
Sbjct: 2694 NCSQCVCEKGELLCQPGGCPLPCG--WSAWSSWAPCDRSCG-SGVRARFR 2740



 Score = 32.7 bits (73), Expect = 2.1
 Identities = 12/24 (50%), Positives = 15/24 (62%), Gaps = 1/24 (4%)

Query: 152  WSPWSPWSKCSAACGQTGVQTRTR 175
            W+ W+PW  CS +CG  G Q R R
Sbjct: 3949 WTSWAPWEPCSRSCG-VGQQRRLR 3971



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 22/87 (25%), Positives = 30/87 (34%), Gaps = 17/87 (19%)

Query: 155  WSPWSKCSAACGQTGVQTRTR---------------ICLAEMVSLCSEASEEGQHCMGQD 199
            W PWS CS  CG  G + RTR                C   +  +C    ++   C    
Sbjct: 3046 WGPWSPCSVPCG-GGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPR-DKQWLDCAQGP 3103

Query: 200  CTACDLTCPMGQVNADCDACMCQDFML 226
             +  +L+ P G        C C   ML
Sbjct: 3104 ASCAELSAPRGTNQTCHPGCHCPSGML 3130


>gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens]
          Length = 1585

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 44/172 (25%), Positives = 62/172 (36%), Gaps = 25/172 (14%)

Query: 55  EWTTWFNIDYPGGKGDYERL-DAIRFYYGDRVCARPLRLEARTTDWTPAGSTGQVVHGSP 113
           EW +W       G+G   R+   +   +G + C  P  L+ +          GQ +   P
Sbjct: 369 EWGSWSLCSRSCGRGSRSRMRTCVPPQHGGKACEGP-ELQTKLCSMAACPVEGQWLEWGP 427

Query: 114 REGFW------CLNREQRPGQNCSNYTVRFLCPPGSLRRD----------TERIWSPWSP 157
               W      C N  Q+  + CS     +    G+L             T+  W PW+ 
Sbjct: 428 ----WGPCSTSCANGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPATDSKWGPWNA 483

Query: 158 WSKCSAACGQTGVQTRTRICLAEMVS--LCSEASEEGQHCMGQDCTACDLTC 207
           WS CS  C  TG Q R R+C A       C    EE + C  + C A    C
Sbjct: 484 WSLCSKTC-DTGWQRRFRMCQATGTQGYPCEGTGEEVKPCSEKRCPAFHEMC 534



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 24/56 (42%), Positives = 30/56 (53%), Gaps = 8/56 (14%)

Query: 155 WSPWSKCSAACGQTGVQTRTRICLAEMV-SLCSEASEEGQHCMGQDCTACDLTCPM 209
           WSPWS CS  CGQ G+Q RTR C++    +LCS    E + C          TCP+
Sbjct: 315 WSPWSVCSLTCGQ-GLQVRTRSCVSSPYGTLCSGPLRETRPCNN------SATCPV 363



 Score = 36.2 bits (82), Expect = 0.19
 Identities = 29/103 (28%), Positives = 38/103 (36%), Gaps = 28/103 (27%)

Query: 122 REQRPGQNCSNYTVRFLCPPGSLRRDTERIWSPWSPWSKCSAACGQTGVQTRTRICLAE- 180
           RE RP  N +       CP          +W  W  WS CS +CG+ G ++R R C+   
Sbjct: 350 RETRPCNNSAT------CP-------VHGVWEEWGSWSLCSRSCGR-GSRSRMRTCVPPQ 395

Query: 181 -----------MVSLCSEAS--EEGQHCMGQDCTACDLTCPMG 210
                         LCS A+   EGQ         C  +C  G
Sbjct: 396 HGGKACEGPELQTKLCSMAACPVEGQWLEWGPWGPCSTSCANG 438


>gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens]
          Length = 1522

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 55/214 (25%), Positives = 73/214 (34%), Gaps = 37/214 (17%)

Query: 15  EVTSVLGRQTMLTQSVRRVQPGKKNPSIFAKPADTLESPGE-----WTTWFNIDYPGGKG 69
           E   ++G  T+ +Q  R V   K+ P   A  A  +   GE     W+ W       G+G
Sbjct: 252 EEFGMMGDHTIKSQRPRSVHE-KRVPQEQADAAKFMAQTGESGVEEWSQWSTCSVTCGQG 310

Query: 70  DYERLDAIRFYYGDRVCARPLRLEARTT-------------DWTPAGSTGQVVHGSPREG 116
              R       YG   C+ PLR E+R               +W+P            R  
Sbjct: 311 SQVRTRTCVSPYGTH-CSGPLR-ESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRGQRTR 368

Query: 117 FWCLNREQRPGQNCSNYTVRF------LCPPGSLRRDTERIWSPWSPWSKCSAACGQTGV 170
                  Q  G+ C             LCP        +  W  WS WS+CS  C   G 
Sbjct: 369 TRSCTPPQYGGRPCEGPETHHKPCNIALCP-------VDGQWQEWSSWSQCSVTC-SNGT 420

Query: 171 QTRTRICLAEM--VSLCSEASEEGQHCMGQDCTA 202
           Q R+R C A     S C     E + C   +CTA
Sbjct: 421 QQRSRQCTAAAHGGSECRGPWAESRECYNPECTA 454



 Score = 39.7 bits (91), Expect = 0.017
 Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 3/59 (5%)

Query: 152 WSPWSPWSKCSAACGQTGVQTRTRICLAEMVS--LCSEASEEGQHCMGQDCTACDLTCP 208
           W+ W  WS CS +C   G + R R C   +++   C    EE + C  Q C A    CP
Sbjct: 458 WNQWGHWSGCSKSC-DGGWERRIRTCQGAVITGQQCEGTGEEVRRCSEQRCPAPYEICP 515


>gi|110825974 ADAM metallopeptidase with thrombospondin type 1
           motif, 2 isoform 1 preproprotein [Homo sapiens]
          Length = 1211

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 35/94 (37%), Positives = 44/94 (46%), Gaps = 13/94 (13%)

Query: 111 GSPREGFWCLNREQRPGQNCSNYTVRFLCPPGSLRRDTERIWSPWSPWSKCSAACGQTGV 170
           G P +G  C      PG++C      +L P   L+RD    W  WSP+  CS  CG TGV
Sbjct: 531 GPPLDGTMCA-----PGKHCFKGHCIWLTPD-ILKRDGS--WGAWSPFGSCSRTCG-TGV 581

Query: 171 QTRTRIC----LAEMVSLCSEASEEGQHCMGQDC 200
           + RTR C     A     CS  + + Q C  QDC
Sbjct: 582 KFRTRQCDNPHPANGGRTCSGLAYDFQLCSRQDC 615



 Score = 32.0 bits (71), Expect = 3.6
 Identities = 23/95 (24%), Positives = 39/95 (41%), Gaps = 23/95 (24%)

Query: 135 VRFLCPPGSLRRDTERIWSPWSPWSKCSAACGQTGVQTRTRICLAEM---------VSLC 185
           +R  C P   +  ++ +W     W  CS  CG+TG+Q R+  C+  +            C
Sbjct: 904 IRRACNP---QECSQPVWVT-GEWEPCSQTCGRTGMQVRSVRCIQPLHDNTTRSVHAKHC 959

Query: 186 SEASEEGQH-CMGQDC---------TACDLTCPMG 210
           ++A  E +  C  + C         + C +TC  G
Sbjct: 960 NDARPESRRACSRELCPGRWRAGPWSQCSVTCGNG 994


>gi|40317626 thrombospondin 1 precursor [Homo sapiens]
          Length = 1170

 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 20/105 (19%)

Query: 126 PGQNCSNYTVRF--LCPPGSLRRDTERIWSPWSPWSKCSAACGQTGVQTRTRICLAEMVS 183
           P   CSN TV     CP        +  WSPWS W+ CS +CG  G+Q R R C   + +
Sbjct: 354 PIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCG-NGIQQRGRSC-DSLNN 411

Query: 184 LCSEASEEGQHCMGQDC----------------TACDLTCPMGQV 212
            C  +S + + C  Q+C                ++C +TC  G +
Sbjct: 412 RCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVI 456



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 31/98 (31%), Positives = 42/98 (42%), Gaps = 19/98 (19%)

Query: 119 CLNREQRPGQNCSNYTVRFLCPPGSLRRDTERI------------WSPWSPWSKCSAACG 166
           C N  Q+ G++C +   R  C   S++  T  I            WS WSPWS CS  CG
Sbjct: 395 CGNGIQQRGRSCDSLNNR--CEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCG 452

Query: 167 QTGVQTRTRICLAEMVSL----CSEASEEGQHCMGQDC 200
             GV TR R+C +    +    C   + E + C    C
Sbjct: 453 D-GVITRIRLCNSPSPQMNGKPCEGEARETKACKKDAC 489



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 23/53 (43%), Positives = 25/53 (47%), Gaps = 5/53 (9%)

Query: 152 WSPWSPWSKCSAACGQTGVQTRTRICLAEMVSL----CSEASEEGQHCMGQDC 200
           W PWSPW  CS  CG  GVQ R+R+C           C     E Q C  QDC
Sbjct: 495 WGPWSPWDICSVTCG-GGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDC 546


>gi|19882241 immunoglobulin superfamily, DCC subclass, member 4
           [Homo sapiens]
          Length = 1250

 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 33/112 (29%), Positives = 49/112 (43%), Gaps = 6/112 (5%)

Query: 297 ATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPS--- 353
           AT  AE      P +   PE  +R    +    C+A+G+PRP    W HN   L P+   
Sbjct: 323 ATAAAELRVLAAPAITQAPEALSRTRASTARFVCRASGEPRP-ALRWLHNGAPLRPNGRV 381

Query: 354 -LYKHESKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNP 404
            +      LV+ ++    AG Y C A++ AG +    A L V+  +  P  P
Sbjct: 382 KVQGGGGSLVITQIGLQDAGYYQCVAENSAG-MACAAASLAVVVREGLPSAP 432


>gi|126517478 peroxidasin homolog-like [Homo sapiens]
          Length = 1463

 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 6/101 (5%)

Query: 297 ATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPS--- 353
           A++  E    ++P +   P+     +G +V   C+A G P+P+   W HN+  LD     
Sbjct: 222 ASVTVEEFNCQSPRITFEPQDVEVPSGNTVYFTCRAEGNPKPE-IIWIHNNHSLDLEDDT 280

Query: 354 --LYKHESKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQL 392
                 +  L++R  ++   G Y C A++ AG  K++ A L
Sbjct: 281 RLNVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAML 321



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 37/140 (26%), Positives = 60/140 (42%), Gaps = 6/140 (4%)

Query: 270 DGKSILKITKVKFAPIVLTMPKTSLKAATIKAEFVRAET----PYMVMNPETKARRAGQS 325
           DG  +++ T+     +   M + S   A  ++  +R  +    P  V+ P+      G S
Sbjct: 287 DGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQDTEVLIGTS 346

Query: 326 VSLCCKATGKPRPDKYFWYHNDTLLDPSLY-KHESKLVLRKLQQHQAGEYFCKAQSDAGA 384
            +L C ATG P P   +   N   LD S +    S L L+ + Q   G + C A +  G 
Sbjct: 347 TTLECMATGHPHPLITWTRDNGLELDGSRHVATSSGLYLQNITQRDHGRFTCHANNSHGT 406

Query: 385 VKSKVAQLIVIASDETPCNP 404
           V++  A +IV A  +    P
Sbjct: 407 VQA-AANIIVQAPPQFTVTP 425


>gi|109150416 peroxidasin [Homo sapiens]
          Length = 1479

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 6/110 (5%)

Query: 297 ATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYK 356
           ATI  E +  E P +   P+     +G +V   C+A G P+P+   W  N+  L      
Sbjct: 234 ATITPEELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPE-IIWLRNNNELSMKTDS 292

Query: 357 H-----ESKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETP 401
                 +  L+++  Q+   G Y C A++ AG VK++   L    S   P
Sbjct: 293 RLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARP 342



 Score = 39.7 bits (91), Expect = 0.017
 Identities = 30/100 (30%), Positives = 47/100 (47%), Gaps = 6/100 (6%)

Query: 309 PYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTL---LDPSL-YKHESKLVLR 364
           P  V+ P+      G+SV+L C ATG P P +  W   D     +DP +       L ++
Sbjct: 342 PTFVIQPQNTEVLVGESVTLECSATGHP-PPRISWTRGDRTPLPVDPRVNITPSGGLYIQ 400

Query: 365 KLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNP 404
            + Q  +GEY C A ++  +V +  A +IV A  +    P
Sbjct: 401 NVVQGDSGEYACSATNNIDSVHA-TAFIIVQALPQFTVTP 439



 Score = 30.8 bits (68), Expect = 8.0
 Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 5/89 (5%)

Query: 309 PYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPS---LYKHESKLVLRK 365
           P   + P+ +    GQ+V   C+A G P P    W    + L      L      L +  
Sbjct: 433 PQFTVTPQDRVVIEGQTVDFQCEAKGNP-PPVIAWTKGGSQLSVDRRHLVLSSGTLRISG 491

Query: 366 LQQHQAGEYFCKAQSDAGAVKSKVAQLIV 394
           +  H  G+Y C+A +  G+ K  VA L V
Sbjct: 492 VALHDQGQYECQAVNIIGSQK-VVAHLTV 519


>gi|164698517 MAM domain containing 1 isoform 1 [Homo sapiens]
          Length = 956

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 30/112 (26%), Positives = 49/112 (43%), Gaps = 16/112 (14%)

Query: 321 RAGQSVSLCCKATGKPRPD----KYFWYHNDTLLDPSLYKHESKLVLRKLQQHQAGEYFC 376
           R G+++ L C  TG PRP     K     +D   D S++    ++    +Q+HQ G Y+C
Sbjct: 53  REGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDSSVFNETLRIT--NIQRHQGGRYYC 110

Query: 377 KAQSDAGAVKSKVAQLIVIASDETPCNPVPESYLIRLPHDCFQNATNSFYYD 428
           KA++  G+   K  ++ V   D+           +   H     A   FYY+
Sbjct: 111 KAENGLGSPAIKSIRVDVYYLDDP----------VVTVHQSIGEAKEQFYYE 152



 Score = 32.7 bits (73), Expect = 2.1
 Identities = 40/154 (25%), Positives = 66/154 (42%), Gaps = 15/154 (9%)

Query: 252 LLTQTDSDGRFRIPGLCPDGKSILKITKVKFAPIVLTMPKTSLKAATIKAEFVRAETPYM 311
           ++TQTD D     PG        LK T       V ++    +   +I      +  P  
Sbjct: 387 VITQTDPDVS---PGTTNLDIIDLKFTDFGTYTCVASLKGGGISDISIDVNISSSTVPPN 443

Query: 312 VMNPETKA---RRAGQSVSLCCKATGKPRPDKYFWYHND---TLLDPSLY--KHESKLVL 363
           +  P+ K+    R G ++ L C+ TGKP+P    W   D    + D S+    ++  L +
Sbjct: 444 LTVPQEKSPLVTREGDTIELQCQVTGKPKP-IILWSRADKEVAMPDGSMQMESYDGTLRI 502

Query: 364 RKLQQHQAGEYFCK-AQSDAGAVKSKVA--QLIV 394
             + +  +G Y C+ +Q +   VK + A  QLIV
Sbjct: 503 VNVSREMSGMYRCQTSQYNGFNVKPREALVQLIV 536



 Score = 31.6 bits (70), Expect = 4.7
 Identities = 21/86 (24%), Positives = 34/86 (39%), Gaps = 7/86 (8%)

Query: 311 MVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHESKLVLRKLQQHQ 370
           +V+NP       G++++L C  TG        W  +   L      +   L +  +    
Sbjct: 252 IVVNP-------GEAITLVCVTTGGEPAPSLTWVRSFGTLPEKTVLNGGTLTIPAITSDD 304

Query: 371 AGEYFCKAQSDAGAVKSKVAQLIVIA 396
           AG Y C A ++ G    K   +IV A
Sbjct: 305 AGTYSCIANNNVGNPAKKSTNIIVRA 330


>gi|11321597 kinase insert domain receptor precursor [Homo sapiens]
          Length = 1356

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 27/95 (28%), Positives = 48/95 (50%), Gaps = 3/95 (3%)

Query: 309 PYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPS---LYKHESKLVLRK 365
           P +  N E +    G+S+ + C A+G P P   ++  N+TL++ S   L      L +R+
Sbjct: 667 PTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVLKDGNRNLTIRR 726

Query: 366 LQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDET 400
           +++   G Y C+A S  G  K +   +I  A ++T
Sbjct: 727 VRKEDEGLYTCQACSVLGCAKVEAFFIIEGAQEKT 761


>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
           [Homo sapiens]
          Length = 1093

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 33/121 (27%), Positives = 56/121 (46%), Gaps = 6/121 (4%)

Query: 279 KVKFAPIVLTMPKTSLKAATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRP 338
           K+  A +     + S  + +  A     ETP +V+  E +    G++V+L CKATG P P
Sbjct: 663 KIDDAGVYSCTAQNSAGSISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNP-P 721

Query: 339 DKYFWYHNDTLLDPSLYKH----ESKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIV 394
            +  W+  D  L  +   H       LV++ +    AG Y C+  +  G  ++  +QL V
Sbjct: 722 PRITWFKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGTERAH-SQLSV 780

Query: 395 I 395
           +
Sbjct: 781 L 781


>gi|27886566 mucosa associated lymphoid tissue lymphoma
           translocation protein 1 isoform b [Homo sapiens]
          Length = 813

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 32/99 (32%), Positives = 52/99 (52%), Gaps = 12/99 (12%)

Query: 311 MVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHESKLVLRKLQQHQ 370
           + +NPE+KA  AGQ V LCC+ATG P   +Y W+  +  +      + S+L+   +    
Sbjct: 129 ITVNPESKAVLAGQFVKLCCRATGHPFV-QYQWFKMNKEIPNG---NTSELIFNAVHVKD 184

Query: 371 AGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPVPESY 409
           AG Y C+  ++     S+ +QL V       C+ +PES+
Sbjct: 185 AGFYVCRVNNNFTFEFSQWSQLDV-------CD-IPESF 215


>gi|5803078 mucosa associated lymphoid tissue lymphoma translocation
           protein 1 isoform a [Homo sapiens]
          Length = 824

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 32/99 (32%), Positives = 52/99 (52%), Gaps = 12/99 (12%)

Query: 311 MVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHESKLVLRKLQQHQ 370
           + +NPE+KA  AGQ V LCC+ATG P   +Y W+  +  +      + S+L+   +    
Sbjct: 129 ITVNPESKAVLAGQFVKLCCRATGHPFV-QYQWFKMNKEIPNG---NTSELIFNAVHVKD 184

Query: 371 AGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPVPESY 409
           AG Y C+  ++     S+ +QL V       C+ +PES+
Sbjct: 185 AGFYVCRVNNNFTFEFSQWSQLDV-------CD-IPESF 215



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 27/90 (30%), Positives = 44/90 (48%), Gaps = 10/90 (11%)

Query: 313 MNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHESK---LVLRKLQQH 369
           + P ++    G ++ L C A G P P  Y W+ N+  L      HE+K   +V     +H
Sbjct: 231 VEPTSQKLMPGSTLVLQCVAVGSPIPH-YQWFKNELPLT-----HETKKLYMVPYVDLEH 284

Query: 370 QAGEYFCKAQSDAGAVKSKVAQLIVIASDE 399
           Q G Y+C   +D  +  SK  ++I+  +DE
Sbjct: 285 Q-GTYWCHVYNDRDSQDSKKVEIIIGRTDE 313


>gi|110347423 spondin 1, extracellular matrix protein [Homo sapiens]
          Length = 807

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 26/57 (45%), Positives = 36/57 (63%), Gaps = 5/57 (8%)

Query: 153 SPWSPWSKCSAACGQTGVQTRTRI--CLAEMVSLCSEASEEGQHCMGQDCTA-CDLT 206
           SPWS WS CS  CG+ G++TR R+   LAE+   C+E  E+ + CM  +C   C+LT
Sbjct: 618 SPWSEWSDCSVTCGK-GMRTRQRMLKSLAELGD-CNEDLEQVEKCMLPECPIDCELT 672



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 10/102 (9%)

Query: 120 LNREQRPGQNCS------NYTVRFLCPPGSLRRDTER--IWSPWSPWSKCSAACGQTGVQ 171
           + R  R G+ C+      +  V  L P      DT    I+S WSPWS CS++    G +
Sbjct: 405 IERIARKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKR 464

Query: 172 TRTRICLAEM-VSLCSEASEEGQHCMGQDCTACD-LTCPMGQ 211
            R R+  A++ +S+    +++ Q CMG  C+  D  TC M +
Sbjct: 465 MRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSE 506



 Score = 38.9 bits (89), Expect = 0.029
 Identities = 28/113 (24%), Positives = 43/113 (38%), Gaps = 26/113 (23%)

Query: 113 PREGFWCLNREQRPGQNCSNYTVRFLCPPGSLRRDTERIWSPWSPWSKCSAACGQTGVQT 172
           P +G  C      P +     TV   C P S       + + W  W +CSA CG  G++ 
Sbjct: 532 PEDGSVCT----LPTEETEKCTVNEECSPSSC------LMTEWGEWDECSATCGM-GMKK 580

Query: 173 RTRICLAEMV--SLCSEASEEGQHCMGQDC-------------TACDLTCPMG 210
           R R+        S+C   + + + CM  +C             + C +TC  G
Sbjct: 581 RHRMIKMNPADGSMCKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKG 633



 Score = 35.8 bits (81), Expect = 0.25
 Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 17/74 (22%)

Query: 153 SPWSPWSKCSAACGQTGVQTRTRIC--LAEMVSLCSEASEEGQHC-MGQDCT-------- 201
           S W  WS CS +CG  G+++R R      E  S+C+  +EE + C + ++C+        
Sbjct: 505 SEWITWSPCSISCGM-GMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLMTE 563

Query: 202 -----ACDLTCPMG 210
                 C  TC MG
Sbjct: 564 WGEWDECSATCGMG 577


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 36/156 (23%), Positives = 62/156 (39%), Gaps = 9/156 (5%)

Query: 259   DGRFRIPGLCPDGKSILKITKVKFAPIVLTMPKTSLKAATIKAEFVRAETPYMVMNPETK 318
             D +F I GL    +   ++    FA     + +    A +IK +    E P +    +  
Sbjct: 24182 DKQFTIGGLLEATEYEFRV----FAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDV 24237

Query: 319   ARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHES-----KLVLRKLQQHQAGE 373
               + G++  L C+  G+P PD  ++     L+    YK  S      L +   +Q   G 
Sbjct: 24238 TTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGV 24297

Query: 374   YFCKAQSDAGAVKSKVAQLIVIASDETPCNPVPESY 409
             Y C A ++ G V++    L+       P  P+ E Y
Sbjct: 24298 YTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKY 24333



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 23/106 (21%), Positives = 47/106 (44%), Gaps = 7/106 (6%)

Query: 307  ETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSL---YKHESK--- 360
            E P ++   +    ++G+    C   +G+P+P K  WY  + LL       + H+ +   
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAVISGRPQP-KISWYKEEQLLSTGFKCKFLHDGQEYT 3249

Query: 361  LVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPVP 406
            L+L +     A  Y C+A++D G   +  +  + +    +P   +P
Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP 3295



 Score = 36.2 bits (82), Expect = 0.19
 Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 8/83 (9%)

Query: 323 GQSVSLCCKATGKPRPDKYFWYHNDTLLDPSL------YKHESKLVLRKLQQHQAGEYFC 376
           G+SV+L C  +G P P    WY  D  ++ S+          ++L++R+     +G + C
Sbjct: 911 GESVTLECHISGYPSPT-VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTC 969

Query: 377 KAQSDAGAVKSKVAQLIVIASDE 399
            A ++AG V S    L V  S+E
Sbjct: 970 SAVNEAGTV-STSCYLAVQVSEE 991



 Score = 36.2 bits (82), Expect = 0.19
 Identities = 40/147 (27%), Positives = 52/147 (35%), Gaps = 23/147 (15%)

Query: 323  GQSVSLCCKATGKPRPDKYFWYHNDTLLDPSL-YKH-----ESKLVLRKLQQHQAGEYFC 376
            G   +L     G P+P K  W+ N  LL PS  YK      +  L++   +    GEY C
Sbjct: 3663 GDVATLSVTVIGIPKP-KIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTC 3721

Query: 377  KAQSDAGAV---------------KSKVAQLIVIASDETPCNPVPESYLIRL-PHDCFQN 420
             A +D G                 K    +  V  S E    P P  +L  L P  C Q 
Sbjct: 3722 MASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQG 3781

Query: 421  ATNSFYYDVGRCPVKTCAGQQDNGIRC 447
                F Y V   P  T    ++N   C
Sbjct: 3782 LPAIFEYTVVGEPAPTVTWFKENKQLC 3808



 Score = 35.8 bits (81), Expect = 0.25
 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 8/106 (7%)

Query: 306   AETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHND------TLLDPSLYKHES 359
             ++ P  +  P ++    GQ+V   C+ +G+P P+   W+ N+      + +  S  ++  
Sbjct: 26826 SDAPAFISQPRSQNINEGQNVLFTCEISGEPSPE-IEWFKNNLPISISSNVSISRSRNVY 26884

Query: 360   KLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPV 405
              L +R      +G+Y  KA++  G   S  A L+V+   E P   V
Sbjct: 26885 SLEIRNASVSDSGKYTIKAKNFRGQC-SATASLMVLPLVEEPSREV 26929



 Score = 34.7 bits (78), Expect = 0.55
 Identities = 40/152 (26%), Positives = 61/152 (40%), Gaps = 18/152 (11%)

Query: 258 SDGRFRIPGLCPDGKSILKITKVKFAPIVLTMPKTSLKAATIKAEFVRAET--PYMVMNP 315
           SDGR ++        +I  +TK       L     S +A +     V+AET  P  V   
Sbjct: 59  SDGRAKL--------TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRL 110

Query: 316 ETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHESK------LVLRKLQQH 369
           ++   R G  V L  + TG P P   F Y +   +  SL    S+      L++ +    
Sbjct: 111 QSMTVRQGSQVRLQVRVTGIPTPVVKF-YRDGAEIQSSLDFQISQEGDLYSLLIAEAYPE 169

Query: 370 QAGEYFCKAQSDAGAVKSKVAQLIVIASDETP 401
            +G Y   A +  G   S  A+L+V   +E P
Sbjct: 170 DSGTYSVNATNSVGRATS-TAELLVQGEEEVP 200



 Score = 34.3 bits (77), Expect = 0.72
 Identities = 26/116 (22%), Positives = 52/116 (44%), Gaps = 12/116 (10%)

Query: 298  TIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKH 357
            T +++  R   P  V+ P +     GQ+     K  G+P P+  FW+H+   +  + Y H
Sbjct: 1400 TDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPET-FWFHDGQQI-VNDYTH 1457

Query: 358  E--------SKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPV 405
            +          L++       +GE+   AQ+ AG  +S ++ ++ + + E    P+
Sbjct: 1458 KVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAG--RSSISVILTVEAVEHQVKPM 1511



 Score = 33.9 bits (76), Expect = 0.94
 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 6/88 (6%)

Query: 307  ETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPS-----LYKHESKL 361
            + P +V+ PE      G++    C+ TG P+P K  WY N  L+  S      Y     L
Sbjct: 1793 QKPDIVLYPEPVRVLEGETARFRCRVTGYPQP-KVNWYLNGQLIRKSKRFRVRYDGIHYL 1851

Query: 362  VLRKLQQHQAGEYFCKAQSDAGAVKSKV 389
             +   + +  GE    A++  G ++ KV
Sbjct: 1852 DIVDCKSYDTGEVKVTAENPEGVIEHKV 1879



 Score = 32.7 bits (73), Expect = 2.1
 Identities = 31/123 (25%), Positives = 51/123 (41%), Gaps = 8/123 (6%)

Query: 287   LTMPKTSLKAATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHN 346
             ++ P       TI AE V       V        +AG +V L     GKP P    W  +
Sbjct: 12969 ISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP-TVSWKKD 13027

Query: 347   DTLLDP------SLYKHESKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDET 400
              TLL P      ++ ++   L L  + +  +G+Y   A++ +G+ KS   +L V+     
Sbjct: 13028 GTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGS-KSATIKLKVLDKPGP 13086

Query: 401   PCN 403
             P +
Sbjct: 13087 PAS 13089



 Score = 32.0 bits (71), Expect = 3.6
 Identities = 24/91 (26%), Positives = 34/91 (37%), Gaps = 7/91 (7%)

Query: 309  PYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYK-------HESKL 361
            PY +  P  +    G SV   C+  G P+P  Y+      L     YK        E KL
Sbjct: 1036 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1095

Query: 362  VLRKLQQHQAGEYFCKAQSDAGAVKSKVAQL 392
            V+       AGEY    ++  G   +  + L
Sbjct: 1096 VISMTFADDAGEYTIVVRNKHGETSASASLL 1126



 Score = 32.0 bits (71), Expect = 3.6
 Identities = 30/123 (24%), Positives = 46/123 (37%), Gaps = 6/123 (4%)

Query: 288   TMPKTSLKAATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHND 347
             T   T  +    KA    +  P +V   +     +        KATG+PRP   +     
Sbjct: 26526 TTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGK 26585

Query: 348   TLLDPSLYK-HESK----LVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPC 402
              +     YK  E K    L + K     +G Y C  ++ AG+V S   +L + A  +T  
Sbjct: 26586 AITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSS-CKLTIKAIKDTEA 26644

Query: 403   NPV 405
               V
Sbjct: 26645 QKV 26647



 Score = 31.6 bits (70), Expect = 4.7
 Identities = 26/121 (21%), Positives = 50/121 (41%), Gaps = 6/121 (4%)

Query: 290   PKTSLKAATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTL 349
             P+ ++ A T++   V        M  +T    AG+ V L     G+P P   +++    L
Sbjct: 23415 PRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKL 23474

Query: 350   LDPSLYKHE-----SKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNP 404
              +      E     +KL +R+      GEY  + ++  G   S+  ++I++     P  P
Sbjct: 23475 RESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTT-SETIKVIILDKPGPPTGP 23533

Query: 405   V 405
             +
Sbjct: 23534 I 23534



 Score = 31.2 bits (69), Expect = 6.1
 Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 5/93 (5%)

Query: 316   ETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLY---KHESKLVLRKLQQHQAG 372
             +T   RAG S+ L    +G+P P   +      L   ++    +  S L++ K+ ++ AG
Sbjct: 23149 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAG 23208

Query: 373   EYFCKAQSDAGAVKSKVAQLIVIASDETPCNPV 405
             +Y  +A++ +G  K     L+ +     PC  V
Sbjct: 23209 KYTIEAENQSG--KKSATVLVKVYDTPGPCPSV 23239


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 36/156 (23%), Positives = 62/156 (39%), Gaps = 9/156 (5%)

Query: 259   DGRFRIPGLCPDGKSILKITKVKFAPIVLTMPKTSLKAATIKAEFVRAETPYMVMNPETK 318
             D +F I GL    +   ++    FA     + +    A +IK +    E P +    +  
Sbjct: 24115 DKQFTIGGLLEATEYEFRV----FAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDV 24170

Query: 319   ARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHES-----KLVLRKLQQHQAGE 373
               + G++  L C+  G+P PD  ++     L+    YK  S      L +   +Q   G 
Sbjct: 24171 TTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGV 24230

Query: 374   YFCKAQSDAGAVKSKVAQLIVIASDETPCNPVPESY 409
             Y C A ++ G V++    L+       P  P+ E Y
Sbjct: 24231 YTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKY 24266



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 23/106 (21%), Positives = 47/106 (44%), Gaps = 7/106 (6%)

Query: 307  ETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSL---YKHESK--- 360
            E P ++   +    ++G+    C   +G+P+P K  WY  + LL       + H+ +   
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAVISGRPQP-KISWYKEEQLLSTGFKCKFLHDGQEYT 3249

Query: 361  LVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPVP 406
            L+L +     A  Y C+A++D G   +  +  + +    +P   +P
Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP 3295



 Score = 36.2 bits (82), Expect = 0.19
 Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 8/83 (9%)

Query: 323 GQSVSLCCKATGKPRPDKYFWYHNDTLLDPSL------YKHESKLVLRKLQQHQAGEYFC 376
           G+SV+L C  +G P P    WY  D  ++ S+          ++L++R+     +G + C
Sbjct: 911 GESVTLECHISGYPSPT-VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTC 969

Query: 377 KAQSDAGAVKSKVAQLIVIASDE 399
            A ++AG V S    L V  S+E
Sbjct: 970 SAVNEAGTV-STSCYLAVQVSEE 991



 Score = 36.2 bits (82), Expect = 0.19
 Identities = 40/147 (27%), Positives = 52/147 (35%), Gaps = 23/147 (15%)

Query: 323  GQSVSLCCKATGKPRPDKYFWYHNDTLLDPSL-YKH-----ESKLVLRKLQQHQAGEYFC 376
            G   +L     G P+P K  W+ N  LL PS  YK      +  L++   +    GEY C
Sbjct: 3596 GDVATLSVTVIGIPKP-KIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTC 3654

Query: 377  KAQSDAGAV---------------KSKVAQLIVIASDETPCNPVPESYLIRL-PHDCFQN 420
             A +D G                 K    +  V  S E    P P  +L  L P  C Q 
Sbjct: 3655 MASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQG 3714

Query: 421  ATNSFYYDVGRCPVKTCAGQQDNGIRC 447
                F Y V   P  T    ++N   C
Sbjct: 3715 LPAIFEYTVVGEPAPTVTWFKENKQLC 3741



 Score = 35.8 bits (81), Expect = 0.25
 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 8/106 (7%)

Query: 306   AETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHND------TLLDPSLYKHES 359
             ++ P  +  P ++    GQ+V   C+ +G+P P+   W+ N+      + +  S  ++  
Sbjct: 26759 SDAPAFISQPRSQNINEGQNVLFTCEISGEPSPE-IEWFKNNLPISISSNVSISRSRNVY 26817

Query: 360   KLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPV 405
              L +R      +G+Y  KA++  G   S  A L+V+   E P   V
Sbjct: 26818 SLEIRNASVSDSGKYTIKAKNFRGQC-SATASLMVLPLVEEPSREV 26862



 Score = 34.7 bits (78), Expect = 0.55
 Identities = 40/152 (26%), Positives = 61/152 (40%), Gaps = 18/152 (11%)

Query: 258 SDGRFRIPGLCPDGKSILKITKVKFAPIVLTMPKTSLKAATIKAEFVRAET--PYMVMNP 315
           SDGR ++        +I  +TK       L     S +A +     V+AET  P  V   
Sbjct: 59  SDGRAKL--------TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRL 110

Query: 316 ETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHESK------LVLRKLQQH 369
           ++   R G  V L  + TG P P   F Y +   +  SL    S+      L++ +    
Sbjct: 111 QSMTVRQGSQVRLQVRVTGIPTPVVKF-YRDGAEIQSSLDFQISQEGDLYSLLIAEAYPE 169

Query: 370 QAGEYFCKAQSDAGAVKSKVAQLIVIASDETP 401
            +G Y   A +  G   S  A+L+V   +E P
Sbjct: 170 DSGTYSVNATNSVGRATS-TAELLVQGEEEVP 200



 Score = 34.3 bits (77), Expect = 0.72
 Identities = 26/116 (22%), Positives = 52/116 (44%), Gaps = 12/116 (10%)

Query: 298  TIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKH 357
            T +++  R   P  V+ P +     GQ+     K  G+P P+  FW+H+   +  + Y H
Sbjct: 1400 TDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPET-FWFHDGQQI-VNDYTH 1457

Query: 358  E--------SKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPV 405
            +          L++       +GE+   AQ+ AG  +S ++ ++ + + E    P+
Sbjct: 1458 KVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAG--RSSISVILTVEAVEHQVKPM 1511



 Score = 34.3 bits (77), Expect = 0.72
 Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 11/70 (15%)

Query: 323  GQSVSLCCKATGKPRPDKYFWYHNDTLLDPS----LYKHESK-----LVLRKLQQHQAGE 373
            G++V    + +G P+P+   W+HN  L+ P+     +  ES      L++    +H AG+
Sbjct: 3433 GETVRFHARVSGIPKPEIQ-WFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEH-AGQ 3490

Query: 374  YFCKAQSDAG 383
            Y CKA + AG
Sbjct: 3491 YSCKAANSAG 3500



 Score = 33.9 bits (76), Expect = 0.94
 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 6/88 (6%)

Query: 307  ETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPS-----LYKHESKL 361
            + P +V+ PE      G++    C+ TG P+P K  WY N  L+  S      Y     L
Sbjct: 1793 QKPDIVLYPEPVRVLEGETARFRCRVTGYPQP-KVNWYLNGQLIRKSKRFRVRYDGIHYL 1851

Query: 362  VLRKLQQHQAGEYFCKAQSDAGAVKSKV 389
             +   + +  GE    A++  G ++ KV
Sbjct: 1852 DIVDCKSYDTGEVKVTAENPEGVIEHKV 1879



 Score = 32.7 bits (73), Expect = 2.1
 Identities = 31/123 (25%), Positives = 51/123 (41%), Gaps = 8/123 (6%)

Query: 287   LTMPKTSLKAATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHN 346
             ++ P       TI AE V       V        +AG +V L     GKP P    W  +
Sbjct: 12902 ISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP-TVSWKKD 12960

Query: 347   DTLLDP------SLYKHESKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDET 400
              TLL P      ++ ++   L L  + +  +G+Y   A++ +G+ KS   +L V+     
Sbjct: 12961 GTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGS-KSATIKLKVLDKPGP 13019

Query: 401   PCN 403
             P +
Sbjct: 13020 PAS 13022



 Score = 32.0 bits (71), Expect = 3.6
 Identities = 24/91 (26%), Positives = 34/91 (37%), Gaps = 7/91 (7%)

Query: 309  PYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYK-------HESKL 361
            PY +  P  +    G SV   C+  G P+P  Y+      L     YK        E KL
Sbjct: 1036 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1095

Query: 362  VLRKLQQHQAGEYFCKAQSDAGAVKSKVAQL 392
            V+       AGEY    ++  G   +  + L
Sbjct: 1096 VISMTFADDAGEYTIVVRNKHGETSASASLL 1126



 Score = 32.0 bits (71), Expect = 3.6
 Identities = 30/123 (24%), Positives = 46/123 (37%), Gaps = 6/123 (4%)

Query: 288   TMPKTSLKAATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHND 347
             T   T  +    KA    +  P +V   +     +        KATG+PRP   +     
Sbjct: 26459 TTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGK 26518

Query: 348   TLLDPSLYK-HESK----LVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPC 402
              +     YK  E K    L + K     +G Y C  ++ AG+V S   +L + A  +T  
Sbjct: 26519 AITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSS-CKLTIKAIKDTEA 26577

Query: 403   NPV 405
               V
Sbjct: 26578 QKV 26580



 Score = 31.6 bits (70), Expect = 4.7
 Identities = 26/121 (21%), Positives = 50/121 (41%), Gaps = 6/121 (4%)

Query: 290   PKTSLKAATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTL 349
             P+ ++ A T++   V        M  +T    AG+ V L     G+P P   +++    L
Sbjct: 23348 PRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKL 23407

Query: 350   LDPSLYKHE-----SKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNP 404
              +      E     +KL +R+      GEY  + ++  G   S+  ++I++     P  P
Sbjct: 23408 RESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTT-SETIKVIILDKPGPPTGP 23466

Query: 405   V 405
             +
Sbjct: 23467 I 23467



 Score = 31.2 bits (69), Expect = 6.1
 Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 5/93 (5%)

Query: 316   ETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLY---KHESKLVLRKLQQHQAG 372
             +T   RAG S+ L    +G+P P   +      L   ++    +  S L++ K+ ++ AG
Sbjct: 23082 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAG 23141

Query: 373   EYFCKAQSDAGAVKSKVAQLIVIASDETPCNPV 405
             +Y  +A++ +G  K     L+ +     PC  V
Sbjct: 23142 KYTIEAENQSG--KKSATVLVKVYDTPGPCPSV 23172


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 36/156 (23%), Positives = 62/156 (39%), Gaps = 9/156 (5%)

Query: 259   DGRFRIPGLCPDGKSILKITKVKFAPIVLTMPKTSLKAATIKAEFVRAETPYMVMNPETK 318
             D +F I GL    +   ++    FA     + +    A +IK +    E P +    +  
Sbjct: 23990 DKQFTIGGLLEATEYEFRV----FAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDV 24045

Query: 319   ARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHES-----KLVLRKLQQHQAGE 373
               + G++  L C+  G+P PD  ++     L+    YK  S      L +   +Q   G 
Sbjct: 24046 TTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGV 24105

Query: 374   YFCKAQSDAGAVKSKVAQLIVIASDETPCNPVPESY 409
             Y C A ++ G V++    L+       P  P+ E Y
Sbjct: 24106 YTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKY 24141



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 23/106 (21%), Positives = 47/106 (44%), Gaps = 7/106 (6%)

Query: 307  ETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSL---YKHESK--- 360
            E P ++   +    ++G+    C   +G+P+P K  WY  + LL       + H+ +   
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAVISGRPQP-KISWYKEEQLLSTGFKCKFLHDGQEYT 3249

Query: 361  LVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPVP 406
            L+L +     A  Y C+A++D G   +  +  + +    +P   +P
Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP 3295



 Score = 36.2 bits (82), Expect = 0.19
 Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 8/83 (9%)

Query: 323 GQSVSLCCKATGKPRPDKYFWYHNDTLLDPSL------YKHESKLVLRKLQQHQAGEYFC 376
           G+SV+L C  +G P P    WY  D  ++ S+          ++L++R+     +G + C
Sbjct: 911 GESVTLECHISGYPSPT-VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTC 969

Query: 377 KAQSDAGAVKSKVAQLIVIASDE 399
            A ++AG V S    L V  S+E
Sbjct: 970 SAVNEAGTV-STSCYLAVQVSEE 991



 Score = 36.2 bits (82), Expect = 0.19
 Identities = 40/147 (27%), Positives = 52/147 (35%), Gaps = 23/147 (15%)

Query: 323  GQSVSLCCKATGKPRPDKYFWYHNDTLLDPSL-YKH-----ESKLVLRKLQQHQAGEYFC 376
            G   +L     G P+P K  W+ N  LL PS  YK      +  L++   +    GEY C
Sbjct: 3471 GDVATLSVTVIGIPKP-KIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTC 3529

Query: 377  KAQSDAGAV---------------KSKVAQLIVIASDETPCNPVPESYLIRL-PHDCFQN 420
             A +D G                 K    +  V  S E    P P  +L  L P  C Q 
Sbjct: 3530 MASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQG 3589

Query: 421  ATNSFYYDVGRCPVKTCAGQQDNGIRC 447
                F Y V   P  T    ++N   C
Sbjct: 3590 LPAIFEYTVVGEPAPTVTWFKENKQLC 3616



 Score = 35.8 bits (81), Expect = 0.25
 Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 8/106 (7%)

Query: 306   AETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHND------TLLDPSLYKHES 359
             ++ P  +  P ++    GQ+V   C+ +G+P P+   W+ N+      + +  S  ++  
Sbjct: 26634 SDAPAFISQPRSQNINEGQNVLFTCEISGEPSPE-IEWFKNNLPISISSNVSISRSRNVY 26692

Query: 360   KLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPV 405
              L +R      +G+Y  KA++  G   S  A L+V+   E P   V
Sbjct: 26693 SLEIRNASVSDSGKYTIKAKNFRGQC-SATASLMVLPLVEEPSREV 26737



 Score = 34.7 bits (78), Expect = 0.55
 Identities = 40/152 (26%), Positives = 61/152 (40%), Gaps = 18/152 (11%)

Query: 258 SDGRFRIPGLCPDGKSILKITKVKFAPIVLTMPKTSLKAATIKAEFVRAET--PYMVMNP 315
           SDGR ++        +I  +TK       L     S +A +     V+AET  P  V   
Sbjct: 59  SDGRAKL--------TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRL 110

Query: 316 ETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHESK------LVLRKLQQH 369
           ++   R G  V L  + TG P P   F Y +   +  SL    S+      L++ +    
Sbjct: 111 QSMTVRQGSQVRLQVRVTGIPTPVVKF-YRDGAEIQSSLDFQISQEGDLYSLLIAEAYPE 169

Query: 370 QAGEYFCKAQSDAGAVKSKVAQLIVIASDETP 401
            +G Y   A +  G   S  A+L+V   +E P
Sbjct: 170 DSGTYSVNATNSVGRATS-TAELLVQGEEEVP 200



 Score = 34.3 bits (77), Expect = 0.72
 Identities = 26/116 (22%), Positives = 52/116 (44%), Gaps = 12/116 (10%)

Query: 298  TIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKH 357
            T +++  R   P  V+ P +     GQ+     K  G+P P+  FW+H+   +  + Y H
Sbjct: 1400 TDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPET-FWFHDGQQI-VNDYTH 1457

Query: 358  E--------SKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPV 405
            +          L++       +GE+   AQ+ AG  +S ++ ++ + + E    P+
Sbjct: 1458 KVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAG--RSSISVILTVEAVEHQVKPM 1511



 Score = 33.9 bits (76), Expect = 0.94
 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 6/88 (6%)

Query: 307  ETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPS-----LYKHESKL 361
            + P +V+ PE      G++    C+ TG P+P K  WY N  L+  S      Y     L
Sbjct: 1793 QKPDIVLYPEPVRVLEGETARFRCRVTGYPQP-KVNWYLNGQLIRKSKRFRVRYDGIHYL 1851

Query: 362  VLRKLQQHQAGEYFCKAQSDAGAVKSKV 389
             +   + +  GE    A++  G ++ KV
Sbjct: 1852 DIVDCKSYDTGEVKVTAENPEGVIEHKV 1879



 Score = 32.7 bits (73), Expect = 2.1
 Identities = 31/123 (25%), Positives = 51/123 (41%), Gaps = 8/123 (6%)

Query: 287   LTMPKTSLKAATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHN 346
             ++ P       TI AE V       V        +AG +V L     GKP P    W  +
Sbjct: 12777 ISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP-TVSWKKD 12835

Query: 347   DTLLDP------SLYKHESKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDET 400
              TLL P      ++ ++   L L  + +  +G+Y   A++ +G+ KS   +L V+     
Sbjct: 12836 GTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGS-KSATIKLKVLDKPGP 12894

Query: 401   PCN 403
             P +
Sbjct: 12895 PAS 12897



 Score = 32.0 bits (71), Expect = 3.6
 Identities = 24/91 (26%), Positives = 34/91 (37%), Gaps = 7/91 (7%)

Query: 309  PYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYK-------HESKL 361
            PY +  P  +    G SV   C+  G P+P  Y+      L     YK        E KL
Sbjct: 1036 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1095

Query: 362  VLRKLQQHQAGEYFCKAQSDAGAVKSKVAQL 392
            V+       AGEY    ++  G   +  + L
Sbjct: 1096 VISMTFADDAGEYTIVVRNKHGETSASASLL 1126



 Score = 32.0 bits (71), Expect = 3.6
 Identities = 30/123 (24%), Positives = 46/123 (37%), Gaps = 6/123 (4%)

Query: 288   TMPKTSLKAATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHND 347
             T   T  +    KA    +  P +V   +     +        KATG+PRP   +     
Sbjct: 26334 TTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGK 26393

Query: 348   TLLDPSLYK-HESK----LVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPC 402
              +     YK  E K    L + K     +G Y C  ++ AG+V S   +L + A  +T  
Sbjct: 26394 AITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSS-CKLTIKAIKDTEA 26452

Query: 403   NPV 405
               V
Sbjct: 26453 QKV 26455



 Score = 31.6 bits (70), Expect = 4.7
 Identities = 26/121 (21%), Positives = 50/121 (41%), Gaps = 6/121 (4%)

Query: 290   PKTSLKAATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTL 349
             P+ ++ A T++   V        M  +T    AG+ V L     G+P P   +++    L
Sbjct: 23223 PRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKL 23282

Query: 350   LDPSLYKHE-----SKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNP 404
              +      E     +KL +R+      GEY  + ++  G   S+  ++I++     P  P
Sbjct: 23283 RESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTT-SETIKVIILDKPGPPTGP 23341

Query: 405   V 405
             +
Sbjct: 23342 I 23342



 Score = 31.2 bits (69), Expect = 6.1
 Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 5/93 (5%)

Query: 316   ETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLY---KHESKLVLRKLQQHQAG 372
             +T   RAG S+ L    +G+P P   +      L   ++    +  S L++ K+ ++ AG
Sbjct: 22957 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAG 23016

Query: 373   EYFCKAQSDAGAVKSKVAQLIVIASDETPCNPV 405
             +Y  +A++ +G  K     L+ +     PC  V
Sbjct: 23017 KYTIEAENQSG--KKSATVLVKVYDTPGPCPSV 23047


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 26/75 (34%), Positives = 35/75 (46%), Gaps = 17/75 (22%)

Query: 152  WSPWSPWSKCSAACGQTGVQTRTRIC----LAEMVSLCSEASEEGQHCMGQDC------- 200
            WS W PW  CS +CG+ G QTR R+C     A   S C  A  + Q C  ++C       
Sbjct: 4646 WSAWQPWGTCSESCGK-GTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCPIHGKWA 4704

Query: 201  -----TACDLTCPMG 210
                 +AC ++C  G
Sbjct: 4705 TWASWSACSVSCGGG 4719



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 3/67 (4%)

Query: 323  GQSVSLCCKATGKPRPDKYFWYHNDTLLDPSL--YKHESKLVLRKLQQHQAGEYFCKAQS 380
            G+ + L CKATG P P K  W  N+ ++          S+LV+ ++ +  +G Y C A++
Sbjct: 4274 GEQLRLSCKATGIPLP-KLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAEN 4332

Query: 381  DAGAVKS 387
              G VK+
Sbjct: 4333 SVGFVKA 4339



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 26/83 (31%), Positives = 38/83 (45%), Gaps = 4/83 (4%)

Query: 307 ETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPS---LYKHESKLVL 363
           E P + + P+ ++   G  VS+ C ATG P+P K  W  ND  +  S       +  L +
Sbjct: 610 EPPKVTVMPKNQSFTGGSEVSIMCSATGYPKP-KIAWTVNDMFIVGSHRYRMTSDGTLFI 668

Query: 364 RKLQQHQAGEYFCKAQSDAGAVK 386
           +      AG Y C A + AG  K
Sbjct: 669 KNAAPKDAGIYGCLASNSAGTDK 691



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 37/123 (30%), Positives = 49/123 (39%), Gaps = 43/123 (34%)

Query: 55   EWTTWFNIDYPGGKGDYERLDAIRFYYGDRVCARPLRLEARTTDWTPAGSTGQVVHGSPR 114
            +W+ W       GKG  +R          R+C +PL          PA        G P 
Sbjct: 4534 QWSAWRACSVTCGKGIQKR---------SRLCNQPL----------PANG------GKPC 4568

Query: 115  EGFWCLNREQRPGQNCSNYTVRFLCPPGSLRRDTERIWSPWSPWSKCSAACGQTGVQTRT 174
            +G    + E R   NC N      CP        +  WS WS W +C+ +CG+ G QTRT
Sbjct: 4569 QGS---DLEMR---NCQNKP----CP-------VDGSWSEWSLWEECTRSCGR-GNQTRT 4610

Query: 175  RIC 177
            R C
Sbjct: 4611 RTC 4613



 Score = 39.7 bits (91), Expect = 0.017
 Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 9/87 (10%)

Query: 307  ETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLL---DP--SLYKHESKL 361
            E PY   N   + R A Q +   C A G P+P    W HN   L   +P  S+ +  + L
Sbjct: 1268 EPPY---NTTFQERVANQRIEFPCPAKGTPKPT-IKWLHNGRELTGREPGISILEDGTLL 1323

Query: 362  VLRKLQQHQAGEYFCKAQSDAGAVKSK 388
            V+  +  +  GEY C A ++AG  + K
Sbjct: 1324 VIASVTPYDNGEYICVAVNEAGTTERK 1350



 Score = 37.4 bits (85), Expect = 0.085
 Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 5/77 (6%)

Query: 323  GQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKH----ESKLVLRKLQQHQAGEYFCKA 378
            G  V+L CKA+G P+P    W     L+  S  K     +  L +      ++GEY C A
Sbjct: 995  GIPVTLPCKASGNPKPS-VIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTA 1053

Query: 379  QSDAGAVKSKVAQLIVI 395
             + AG  K KV   + +
Sbjct: 1054 TNTAGYAKRKVQLTVYV 1070



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 5/53 (9%)

Query: 152  WSPWSPWSKCSAACGQTGVQTRTRICLAEMVS----LCSEASEEGQHCMGQDC 200
            +S WS W  CS  CG+ G+Q R+R+C   + +     C  +  E ++C  + C
Sbjct: 4532 FSQWSAWRACSVTCGK-GIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPC 4583



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 14/26 (53%), Positives = 18/26 (69%), Gaps = 1/26 (3%)

Query: 152  WSPWSPWSKCSAACGQTGVQTRTRIC 177
            W  W  WS+CSA+CG  G +TR R+C
Sbjct: 4817 WGSWHSWSQCSASCG-GGEKTRKRLC 4841



 Score = 36.2 bits (82), Expect = 0.19
 Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 5/124 (4%)

Query: 270 DGKSILKITKVKFAPIVLTMPKTSLKAATIKAEFVRAETPYMVMNPETKARRAGQSVSLC 329
           DG   +K    K A I   +   S       +     E P +++         G    + 
Sbjct: 663 DGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVME 722

Query: 330 CKATGKPRPDKYFWYHNDTLLDPSLYKHESKLV-LRKLQQHQ---AGEYFCKAQSDAGAV 385
           CK +G P P +  W+  D  L PS +     L+ L K+Q+ Q   AG+Y C A ++AG  
Sbjct: 723 CKTSGIP-PPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRA 781

Query: 386 KSKV 389
             K+
Sbjct: 782 TGKI 785



 Score = 33.9 bits (76), Expect = 0.94
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 6/90 (6%)

Query: 309 PYMVMNPETKARRAGQSVSL-CCKATGKPRPDKYFWYHNDTLLDPSLY---KHESKLVLR 364
           P + ++P       GQ ++L C    G P P++  W  N  +L  + Y   + +  L + 
Sbjct: 890 PLIGISPSVANVIEGQQLTLPCTLLAGNPIPERR-WIKNSAMLLQNPYITVRSDGSLHIE 948

Query: 365 KLQQHQAGEYFCKAQSDAGAVKSKVAQLIV 394
           ++Q    GEY C A + AG   +K   ++V
Sbjct: 949 RVQLQDGGEYTCVASNVAG-TNNKTTSVVV 977



 Score = 33.9 bits (76), Expect = 0.94
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 5/67 (7%)

Query: 321  RAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPS----LYKHESKLVLRKLQQHQAGEYFC 376
            R G SVSL C++   P P    WY N  ++  S    +      L ++K +    G+Y C
Sbjct: 3072 REGTSVSLECESNAVP-PPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVC 3130

Query: 377  KAQSDAG 383
            +A + AG
Sbjct: 3131 RAINVAG 3137



 Score = 32.7 bits (73), Expect = 2.1
 Identities = 22/90 (24%), Positives = 41/90 (45%), Gaps = 4/90 (4%)

Query: 309  PYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWY---HNDTLLDPSLYKHESKLVLRK 365
            P + + P      AG  + L C+ATG+P+P    W    H+ +  D       + L +  
Sbjct: 4440 PIITLEPVETVINAGGKIILNCQATGEPQP-TITWSRQGHSISWDDRVNVLSNNSLYIAD 4498

Query: 366  LQQHQAGEYFCKAQSDAGAVKSKVAQLIVI 395
             Q+    E+ C A++  G+V  +V  ++ +
Sbjct: 4499 AQKEDTSEFECVARNLMGSVLVRVPVIVQV 4528



 Score = 32.0 bits (71), Expect = 3.6
 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 6/78 (7%)

Query: 324  QSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHESK----LVLRKLQQHQAGEYFCKAQ 379
            QSV+L C+ TG P P+   W+ +   L      H       L +  +Q    G Y C A 
Sbjct: 2495 QSVTLTCEVTGNPVPE-ITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLAS 2553

Query: 380  SDAGAVKSKVAQLIVIAS 397
            S AG  KS+   L V  S
Sbjct: 2554 SPAGH-KSRSFSLNVFVS 2570



 Score = 32.0 bits (71), Expect = 3.6
 Identities = 13/26 (50%), Positives = 13/26 (50%), Gaps = 1/26 (3%)

Query: 152  WSPWSPWSKCSAACGQTGVQTRTRIC 177
            WSPWS W  CS  C   G   R R C
Sbjct: 4760 WSPWSGWGTCSRTC-NGGQMRRYRTC 4784



 Score = 31.6 bits (70), Expect = 4.7
 Identities = 22/66 (33%), Positives = 29/66 (43%), Gaps = 3/66 (4%)

Query: 323  GQSVSLCCKATGKPRPDKYFWYHNDTL-LDPSLY--KHESKLVLRKLQQHQAGEYFCKAQ 379
            G S S+ C   G P P   +      L LD  L    H   L L K +   +G+Y C A 
Sbjct: 3450 GSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIAS 3509

Query: 380  SDAGAV 385
            ++AG V
Sbjct: 3510 NEAGEV 3515


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,365,898
Number of Sequences: 37866
Number of extensions: 2366716
Number of successful extensions: 6534
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 69
Number of HSP's successfully gapped in prelim test: 208
Number of HSP's that attempted gapping in prelim test: 5310
Number of HSP's gapped (non-prelim): 1271
length of query: 1184
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1071
effective length of database: 13,968,660
effective search space: 14960434860
effective search space used: 14960434860
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.