BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|190341087 spondin 2, extracellular matrix protein [Homo sapiens] (331 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|190341087 spondin 2, extracellular matrix protein [Homo sapiens] 682 0.0 gi|6912682 spondin 2, extracellular matrix protein [Homo sapiens] 682 0.0 gi|110347423 spondin 1, extracellular matrix protein [Homo sapiens] 173 2e-43 gi|122937257 thrombospondin, type I, domain containing 7B [Homo ... 59 8e-09 gi|150170672 thrombospondin, type I, domain containing 7A [Homo ... 55 7e-08 gi|209969800 RPE-spondin [Homo sapiens] 49 8e-06 gi|134031945 SCO-spondin [Homo sapiens] 43 4e-04 gi|84490388 R-spondin1 [Homo sapiens] 42 8e-04 gi|18490982 R-spondin 3 [Homo sapiens] 41 0.002 gi|222446611 R-spondin family, member 2 [Homo sapiens] 40 0.002 gi|4557391 complement component 8, beta polypeptide preproprotei... 38 0.011 gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [... 38 0.011 gi|145699139 cartilage intermediate layer protein 2 [Homo sapiens] 37 0.024 gi|192449445 cartilage intermediate layer protein [Homo sapiens] 36 0.042 gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens] 35 0.071 gi|118572606 hemicentin 1 [Homo sapiens] 35 0.093 gi|209977117 unc-5 homolog D [Homo sapiens] 35 0.12 gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens] 34 0.21 gi|4505737 complement factor properdin precursor [Homo sapiens] 33 0.35 gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens] 33 0.35 gi|223671861 complement factor properdin precursor [Homo sapiens] 33 0.35 gi|4502511 complement component 9 precursor [Homo sapiens] 33 0.46 gi|158187511 T-box 22 isoform 2 [Homo sapiens] 33 0.46 gi|158187509 T-box 22 isoform 1 [Homo sapiens] 33 0.46 gi|18375603 T-box 22 isoform 1 [Homo sapiens] 33 0.46 gi|122937388 MAX gene associated [Homo sapiens] 33 0.46 gi|16933525 unc5C [Homo sapiens] 32 0.78 gi|110611170 ADAM metallopeptidase with thrombospondin type 1 mo... 32 0.78 gi|40317626 thrombospondin 1 precursor [Homo sapiens] 32 1.0 gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 32 1.0 >gi|190341087 spondin 2, extracellular matrix protein [Homo sapiens] Length = 331 Score = 682 bits (1759), Expect = 0.0 Identities = 331/331 (100%), Positives = 331/331 (100%) Query: 1 MENPSPAAALGKALCALLLATLGAAGQPLGGESICSARAPAKYSITFTGKWSQTAFPKQY 60 MENPSPAAALGKALCALLLATLGAAGQPLGGESICSARAPAKYSITFTGKWSQTAFPKQY Sbjct: 1 MENPSPAAALGKALCALLLATLGAAGQPLGGESICSARAPAKYSITFTGKWSQTAFPKQY 60 Query: 61 PLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEIEAAGEALQSV 120 PLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEIEAAGEALQSV Sbjct: 61 PLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEIEAAGEALQSV 120 Query: 121 HAVFSAPAVPSGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGDRWREQA 180 HAVFSAPAVPSGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGDRWREQA Sbjct: 121 HAVFSAPAVPSGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGDRWREQA 180 Query: 181 ALDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYPRLKALPPIARVT 240 ALDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYPRLKALPPIARVT Sbjct: 181 ALDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYPRLKALPPIARVT 240 Query: 241 LVRLRQSPRAFIPPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKS 300 LVRLRQSPRAFIPPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKS Sbjct: 241 LVRLRQSPRAFIPPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKS 300 Query: 301 RTRYVRVQPANNGSPCPELEEEAECVPDNCV 331 RTRYVRVQPANNGSPCPELEEEAECVPDNCV Sbjct: 301 RTRYVRVQPANNGSPCPELEEEAECVPDNCV 331 >gi|6912682 spondin 2, extracellular matrix protein [Homo sapiens] Length = 331 Score = 682 bits (1759), Expect = 0.0 Identities = 331/331 (100%), Positives = 331/331 (100%) Query: 1 MENPSPAAALGKALCALLLATLGAAGQPLGGESICSARAPAKYSITFTGKWSQTAFPKQY 60 MENPSPAAALGKALCALLLATLGAAGQPLGGESICSARAPAKYSITFTGKWSQTAFPKQY Sbjct: 1 MENPSPAAALGKALCALLLATLGAAGQPLGGESICSARAPAKYSITFTGKWSQTAFPKQY 60 Query: 61 PLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEIEAAGEALQSV 120 PLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEIEAAGEALQSV Sbjct: 61 PLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEIEAAGEALQSV 120 Query: 121 HAVFSAPAVPSGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGDRWREQA 180 HAVFSAPAVPSGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGDRWREQA Sbjct: 121 HAVFSAPAVPSGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGDRWREQA 180 Query: 181 ALDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYPRLKALPPIARVT 240 ALDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYPRLKALPPIARVT Sbjct: 181 ALDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYPRLKALPPIARVT 240 Query: 241 LVRLRQSPRAFIPPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKS 300 LVRLRQSPRAFIPPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKS Sbjct: 241 LVRLRQSPRAFIPPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKS 300 Query: 301 RTRYVRVQPANNGSPCPELEEEAECVPDNCV 331 RTRYVRVQPANNGSPCPELEEEAECVPDNCV Sbjct: 301 RTRYVRVQPANNGSPCPELEEEAECVPDNCV 331 >gi|110347423 spondin 1, extracellular matrix protein [Homo sapiens] Length = 807 Score = 173 bits (439), Expect = 2e-43 Identities = 113/331 (34%), Positives = 164/331 (49%), Gaps = 21/331 (6%) Query: 9 ALGKALCALLLATLGAAGQPLGGESICSARAPAKYSITFTGKWSQTAFPKQYPLFRPPAQ 68 +L K LC G +P+ C A AKY +TF G WS+ PK YP R Sbjct: 176 SLTKKLCEQDSTFDGVTDKPILD---CCACGTAKYRLTFYGNWSEKTHPKDYP--RRANH 230 Query: 69 WSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEI-EAAGEALQSVHAVFSAP 127 WS+++G +HS +Y +W Y S G++ AE G + +EI + + E L + A P Sbjct: 231 WSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWP 290 Query: 128 AVP--SGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGD-RWREQAALDL 184 A + SAE V R L+SF+ + PSPDW VG+ + DLC + W ++ DL Sbjct: 291 AWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDL 350 Query: 185 YPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYPRLKALPPIARVTLVRL 244 P+DAGTDSG T+ SPN TIPQ+ + +TS HP + FY P ++ +ARV + R+ Sbjct: 351 IPWDAGTDSGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERI 408 Query: 245 -RQSPRAFIPPAPVLPSRDNEIVDSA----SVPETPLDCEVSLWSSWGLCGGHCGRLGTK 299 R+ + I P V D+ + D A +TP C S WS W C G + Sbjct: 409 ARKGEQCNIVPDNV----DDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKR 464 Query: 300 SRTRYVRVQPANNGSPCPELEEEAECVPDNC 330 R R ++ Q + PCP+ ++ C+ C Sbjct: 465 MRQRMLKAQ-LDLSVPCPDTQDFQPCMGPGC 494 Score = 63.9 bits (154), Expect = 2e-10 Identities = 27/72 (37%), Positives = 42/72 (58%), Gaps = 1/72 (1%) Query: 260 SRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPEL 319 + D E V+ +PE P+DCE++ WS W C CG+ G RTR ++++P G+PCPE Sbjct: 651 NEDLEQVEKCMLPECPIDCELTEWSQWSECNKSCGK-GHVIRTRMIQMEPQFGGAPCPET 709 Query: 320 EEEAECVPDNCV 331 + +C C+ Sbjct: 710 VQRKKCRIRKCL 721 Score = 40.0 bits (92), Expect = 0.003 Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 9/61 (14%) Query: 278 CEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEA-------ECVPDNC 330 C +S W +W C CG +G +SR RYV+ P +GS C EE EC P +C Sbjct: 502 CTMSEWITWSPCSISCG-MGMRSRERYVKQFP-EDGSVCTLPTEETEKCTVNEECSPSSC 559 Query: 331 V 331 + Sbjct: 560 L 560 Score = 39.3 bits (90), Expect = 0.005 Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 3/58 (5%) Query: 274 TPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAE-CVPDNC 330 +P C ++ W W C CG +G K R R +++ PA +GS C +AE C+ C Sbjct: 555 SPSSCLMTEWGEWDECSATCG-MGMKKRHRMIKMNPA-DGSMCKAETSQAEKCMMPEC 610 Score = 31.6 bits (70), Expect = 1.0 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 2/55 (3%) Query: 276 LDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAECVPDNC 330 + C +S WS W C CG+ G ++R R ++ A G +LE+ +C+ C Sbjct: 613 IPCLLSPWSEWSDCSVTCGK-GMRTRQRMLK-SLAELGDCNEDLEQVEKCMLPEC 665 >gi|122937257 thrombospondin, type I, domain containing 7B [Homo sapiens] Length = 1577 Score = 58.5 bits (140), Expect = 8e-09 Identities = 26/68 (38%), Positives = 40/68 (58%), Gaps = 2/68 (2%) Query: 253 PPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANN 312 P P S I + +P P DC++S WSSWG C CG +G + R+++++ +P N Sbjct: 946 PVDPSFCSSSGYIQEKCVIP-CPFDCKLSDWSSWGSCSSSCG-IGVRIRSKWLKEKPYNG 1003 Query: 313 GSPCPELE 320 G PCP+L+ Sbjct: 1004 GRPCPKLD 1011 Score = 48.9 bits (115), Expect = 6e-06 Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 1/59 (1%) Query: 273 ETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCP-ELEEEAECVPDNC 330 E ++C++S W++W C CG G SRTR++ + G PCP EL +E C C Sbjct: 1214 ECVVNCQLSGWTAWTECSQTCGHGGRMSRTRFIIMPTQGEGRPCPTELTQEKTCPVTPC 1272 Score = 48.5 bits (114), Expect = 8e-06 Identities = 25/56 (44%), Positives = 30/56 (53%), Gaps = 4/56 (7%) Query: 275 PLDCEVSLWSSWGLCGGHC--GRL--GTKSRTRYVRVQPANNGSPCPELEEEAECV 326 P DCE S WSSW C C G L G +SR+R V+ G CPEL E+ C+ Sbjct: 303 PKDCETSQWSSWSPCSKTCRSGSLLPGFRSRSRNVKHMAIGGGKECPELLEKEACI 358 Score = 43.9 bits (102), Expect = 2e-04 Identities = 30/84 (35%), Positives = 40/84 (47%), Gaps = 13/84 (15%) Query: 252 IPPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLC-GGHC----GRLGTKSRTRYVR 306 + PAP LPS+ I S DC VS WS+WGLC +C G+ G ++R R+V Sbjct: 436 VGPAP-LPSQLCNIPCST-------DCIVSSWSAWGLCIHENCHDPQGKKGFRTRQRHVL 487 Query: 307 VQPANNGSPCPELEEEAECVPDNC 330 ++ CP L E C C Sbjct: 488 MESTGPAGHCPHLVESVPCEDPMC 511 Score = 40.0 bits (92), Expect = 0.003 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 8/80 (10%) Query: 258 LPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHC--GR----LGTKSRTRYVRVQPAN 311 +P +D+ + SVP P DC ++ WS W C C GR +G +SR+R +Q Sbjct: 1323 MPFQDSILKQLCSVP-CPGDCHLTEWSEWSTCELTCIDGRSFETVGRQSRSRTFIIQSFE 1381 Query: 312 NGSPCP-ELEEEAECVPDNC 330 N CP ++ E C C Sbjct: 1382 NQDSCPQQVLETRPCTGGKC 1401 Score = 39.3 bits (90), Expect = 0.005 Identities = 24/84 (28%), Positives = 35/84 (41%), Gaps = 12/84 (14%) Query: 254 PAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRL---GTKSRTRYVRVQPA 310 P P P R S +P +DC +S W+ W C C G ++R+R + Sbjct: 553 PVPPPPERK-----SCEIP-CRMDCVLSEWTEWSSCSQSCSNKNSDGKQTRSRTILALAG 606 Query: 311 NNGSPCP---ELEEEAECVPDNCV 331 G PCP L+E C +C+ Sbjct: 607 EGGKPCPPSQALQEHRLCNDHSCM 630 Score = 38.9 bits (89), Expect = 0.006 Identities = 23/65 (35%), Positives = 29/65 (44%), Gaps = 2/65 (3%) Query: 267 DSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAEC- 325 + A + P DC VS + W C CG+ + RTR V P G CP L E C Sbjct: 138 EQACLIPCPRDCVVSEFLPWSNCSKGCGK-KLQHRTRAVIAPPLFGGLQCPNLTESRACD 196 Query: 326 VPDNC 330 P +C Sbjct: 197 APISC 201 Score = 34.7 bits (78), Expect = 0.12 Identities = 22/53 (41%), Positives = 27/53 (50%), Gaps = 4/53 (7%) Query: 277 DCEVSLWSSWGLCGGHC--GRLGTK-SRTRYVRVQPANNGSPCPE-LEEEAEC 325 DC V+ +S W C C G K SR R + + AN G CP+ L EE EC Sbjct: 706 DCIVTAFSEWTPCPRMCQAGNATVKQSRYRIIIQEAANGGQECPDTLYEEREC 758 Score = 33.1 bits (74), Expect = 0.35 Identities = 17/57 (29%), Positives = 28/57 (49%), Gaps = 2/57 (3%) Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAEC-VPDNC 330 P +C +S W W C C + RTR++ ++P+ N C E + C + +NC Sbjct: 1096 PNECVMSEWGLWSKCPQSCDPHTMQRRTRHL-LRPSLNSRTCAEDSQVQPCLLNENC 1151 >gi|150170672 thrombospondin, type I, domain containing 7A [Homo sapiens] Length = 1657 Score = 55.5 bits (132), Expect = 7e-08 Identities = 22/55 (40%), Positives = 35/55 (63%), Gaps = 1/55 (1%) Query: 266 VDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELE 320 ++ A + P DC++S WS+W C CG G K R++++R +P N G PCP+L+ Sbjct: 1024 IEEACIIPCPSDCKLSEWSNWSRCSKSCGS-GVKVRSKWLREKPYNGGRPCPKLD 1077 Score = 47.0 bits (110), Expect = 2e-05 Identities = 20/62 (32%), Positives = 34/62 (54%) Query: 266 VDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAEC 325 ++++ + E P++C++S WS W C CG G R R V +G PCP L ++++ Sbjct: 1275 MNTSCMVECPVNCQLSDWSPWSECSQTCGLTGKMIRRRTVTQPFQGDGRPCPSLMDQSKP 1334 Query: 326 VP 327 P Sbjct: 1335 CP 1336 Score = 46.6 bits (109), Expect = 3e-05 Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 4/54 (7%) Query: 277 DCEVSLWSSWGLCGGHCGRL----GTKSRTRYVRVQPANNGSPCPELEEEAECV 326 +C+VS WS W C C + GT+ RTR +R P + CPE EE+ C+ Sbjct: 360 ECQVSEWSEWSPCSKTCHDMVSPAGTRVRTRTIRQFPIGSEKECPEFEEKEPCL 413 Score = 44.3 bits (103), Expect = 2e-04 Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 1/66 (1%) Query: 265 IVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAE 324 +++ A + DC VS +S+W C CG G + RTR+V P GS CP L E Sbjct: 182 LLEQACLIPCQQDCIVSEFSAWSECSKTCGS-GLQHRTRHVVAPPQFGGSGCPNLTEFQV 240 Query: 325 CVPDNC 330 C C Sbjct: 241 CQSSPC 246 Score = 40.4 bits (93), Expect = 0.002 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 7/81 (8%) Query: 257 VLPSRDNEIVDSASVPETPLDCEVSLWSSWGLC------GGHCGRLGTKSRTRYVRVQPA 310 ++ N +++ + P DC + WSSW LC G G G + R+R V +Q Sbjct: 1394 IIDGNKNMVLEESCSQPCPGDCYLKDWSSWSLCQLTCVNGEDLGFGGIQVRSRPVIIQEL 1453 Query: 311 NNGSPCPE-LEEEAECVPDNC 330 N CPE + E C C Sbjct: 1454 ENQHLCPEQMLETKSCYDGQC 1474 Score = 38.9 bits (89), Expect = 0.006 Identities = 22/64 (34%), Positives = 27/64 (42%), Gaps = 8/64 (12%) Query: 275 PLDCEVSLWSSWG-----LCGGHCGRLGTKSRTRYVRVQPANNG---SPCPELEEEAECV 326 P +CEVS WS+WG C G+ G K R R + +P CP L E C Sbjct: 510 PTECEVSPWSAWGPCTYENCNDQQGKKGFKLRKRRITNEPTGGSGVTGNCPHLLEAIPCE 569 Query: 327 PDNC 330 C Sbjct: 570 EPAC 573 Score = 38.5 bits (88), Expect = 0.008 Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 1/57 (1%) Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAEC-VPDNC 330 P DC +S W W C C + + R+ QPA+ G CP E+ C + NC Sbjct: 1163 PEDCVISEWGPWTQCVLPCNQSSFRQRSADPIRQPADEGRSCPNAVEKEPCNLNKNC 1219 Score = 33.5 bits (75), Expect = 0.27 Identities = 11/26 (42%), Positives = 17/26 (65%) Query: 277 DCEVSLWSSWGLCGGHCGRLGTKSRT 302 DC+++ WS + C G CG + T+ RT Sbjct: 906 DCQLTSWSKFSSCNGDCGAVRTRKRT 931 Score = 33.1 bits (74), Expect = 0.35 Identities = 21/60 (35%), Positives = 27/60 (45%), Gaps = 6/60 (10%) Query: 277 DCEVSLWSSWGLCGGHC----GRLGTKSRTRYVRVQPANNGSPC--PELEEEAECVPDNC 330 DC V+ +S W C C + +SR R + PAN G C P EE+A P C Sbjct: 771 DCIVTPYSDWTSCPSSCKEGDSSIRKQSRHRVIIQLPANGGRDCTDPLYEEKACEAPQAC 830 Score = 30.4 bits (67), Expect = 2.3 Identities = 19/63 (30%), Positives = 24/63 (38%), Gaps = 7/63 (11%) Query: 275 PLDCEVSLWSSWGLCGGHCG---RLGTKSRTRYVRVQPANNGS-PCPE---LEEEAECVP 327 P DC +S WS+W C C G + R R + G CP L+E C Sbjct: 632 PKDCVLSTWSTWSSCSHTCSGKTTEGKQIRARSILAYAGEEGGIRCPNSSALQEVRSCNE 691 Query: 328 DNC 330 C Sbjct: 692 HPC 694 >gi|209969800 RPE-spondin [Homo sapiens] Length = 264 Score = 48.5 bits (114), Expect = 8e-06 Identities = 22/49 (44%), Positives = 28/49 (57%), Gaps = 1/49 (2%) Query: 278 CEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAECV 326 C V WS W C C + T+ R R V+ +P N G+PCP LEE A C+ Sbjct: 75 CFVGEWSPWSGCADQC-KPTTRVRRRSVQQEPQNGGAPCPPLEERAGCL 122 >gi|134031945 SCO-spondin [Homo sapiens] Length = 5147 Score = 42.7 bits (99), Expect = 4e-04 Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 1/49 (2%) Query: 283 WSSWGLCGGHCGRLGTKSRTRY-VRVQPANNGSPCPELEEEAECVPDNC 330 WS WG C CG LGT++R+R V P +G C ++ EC +C Sbjct: 3817 WSPWGPCSRSCGGLGTRTRSRQCVLTMPTLSGQGCRGPRQDLECPSPDC 3865 Score = 39.7 bits (91), Expect = 0.004 Identities = 29/81 (35%), Positives = 36/81 (44%), Gaps = 7/81 (8%) Query: 256 PVLPS----RDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTR-YVRVQPA 310 P LP RD S V P+ ++W +WG C CG G +SR R V P Sbjct: 2530 PPLPGGSCPRDRFRSQSCFVQACPVAGAWAMWEAWGPCSVSCGG-GHQSRQRSCVDPPPK 2588 Query: 311 NNGSPCP-ELEEEAECVPDNC 330 N G+PCP +E A C C Sbjct: 2589 NGGAPCPGASQERAPCGLQPC 2609 Score = 36.2 bits (82), Expect = 0.042 Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 5/48 (10%) Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEE 322 P C S WS+W C CG G +SR R + +GS PE EE Sbjct: 4157 PTHCAWSHWSAWSPCSHSCGPRGQQSRFR-----SSTSGSWAPECREE 4199 Score = 35.4 bits (80), Expect = 0.071 Identities = 20/51 (39%), Positives = 25/51 (49%), Gaps = 2/51 (3%) Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPAN-NGSPCPELEEEAE 324 PL C S WSSW C CG G ++R R PA G+PC +E + Sbjct: 2713 PLPCGWSAWSSWAPCDRSCGS-GVRARFRSPSNPPAAWGGAPCEGDRQELQ 2762 Score = 33.9 bits (76), Expect = 0.21 Identities = 21/63 (33%), Positives = 25/63 (39%), Gaps = 10/63 (15%) Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPEL-------EEEAECVP 327 P+D E S WS W +C C GT +R R P N G C L + C Sbjct: 1748 PVDGEWSTWSPWSVCSEPC--RGTMTRQRQCH-SPQNGGRTCAALPGGLHSTRQTKPCPQ 1804 Query: 328 DNC 330 D C Sbjct: 1805 DGC 1807 Score = 32.7 bits (73), Expect = 0.46 Identities = 18/61 (29%), Positives = 26/61 (42%), Gaps = 2/61 (3%) Query: 272 PETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYV-RVQPANNGSPCPELEEEA-ECVPDN 329 P+ +DC S WS W C G CG + R +P+ G C + +A C + Sbjct: 1904 PDCAVDCGWSSWSPWAKCLGPCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEP 1963 Query: 330 C 330 C Sbjct: 1964 C 1964 Score = 31.2 bits (69), Expect = 1.3 Identities = 19/59 (32%), Positives = 23/59 (38%), Gaps = 12/59 (20%) Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVR-----------VQPANNGSPCPELEEE 322 P C+ SLW W C C G + R R Q + NG PCPE E + Sbjct: 4613 PDSCQWSLWGPWSPCQVPCSG-GFRLRWREAEALCGGGCREPWAQESCNGGPCPECEAQ 4670 Score = 30.8 bits (68), Expect = 1.7 Identities = 19/52 (36%), Positives = 23/52 (44%), Gaps = 3/52 (5%) Query: 281 SLWSSWGLCGGHCGRLGTKSRTRYVRVQPA-NNGSPCPELEEEAE-CVPDNC 330 S WS W C CG G R+R P+ N G+PC +A C P C Sbjct: 4008 SRWSPWSWCDRSCGG-GQSLRSRSCSSPPSKNGGAPCAGERHQARLCNPMPC 4058 Score = 30.0 bits (66), Expect = 3.0 Identities = 15/42 (35%), Positives = 19/42 (45%), Gaps = 2/42 (4%) Query: 276 LDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCP 317 +DC ++ WS W C CG T R +R P G CP Sbjct: 2499 VDCVLAPWSVWSSCSRSCGLGLTFQRQELLR--PPLPGGSCP 2538 Score = 29.6 bits (65), Expect = 3.9 Identities = 15/35 (42%), Positives = 19/35 (54%), Gaps = 1/35 (2%) Query: 281 SLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSP 315 +LWSSW C CG G + RTR R ++ SP Sbjct: 4257 TLWSSWSDCPVSCGG-GNQVRTRACRAAAPHHRSP 4290 Score = 28.9 bits (63), Expect = 6.6 Identities = 18/51 (35%), Positives = 23/51 (45%), Gaps = 2/51 (3%) Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPAN-NGSPCPELEEEAE 324 P+ C S W+ W LC C +G + R R PA G+ C EAE Sbjct: 2983 PVACGWSPWTLWSLCSCSC-NVGIRRRFRAGTAPPAAFGGAECQGPTMEAE 3032 Score = 28.5 bits (62), Expect = 8.7 Identities = 21/61 (34%), Positives = 27/61 (44%), Gaps = 10/61 (16%) Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANN----GSPCPELEEE-AECVPDN 329 P +C S WSSW C C L + RY PA+ G+PC L+ C+ N Sbjct: 4363 PEECVWSSWSSWTRCS--CRVL---VQQRYRHQGPASRGARAGAPCTRLDGHFRPCLISN 4417 Query: 330 C 330 C Sbjct: 4418 C 4418 Score = 28.5 bits (62), Expect = 8.7 Identities = 15/48 (31%), Positives = 18/48 (37%), Gaps = 1/48 (2%) Query: 283 WSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAECVPDNC 330 WS+W C CG GT R R P + E+ EC C Sbjct: 4769 WSAWSSCSAPCGG-GTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPC 4815 >gi|84490388 R-spondin1 [Homo sapiens] Length = 263 Score = 42.0 bits (97), Expect = 8e-04 Identities = 26/77 (33%), Positives = 36/77 (46%), Gaps = 8/77 (10%) Query: 253 PPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGH---CG-RLGTKSRTRYVRVQ 308 P P S N ++ +S P CE+S WS WG C CG R G++ RTR V Sbjct: 127 PACPEGSSAANGTMECSS----PAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVLHA 182 Query: 309 PANNGSPCPELEEEAEC 325 P + + C + +E C Sbjct: 183 PVGDHAACSDTKETRRC 199 >gi|18490982 R-spondin 3 [Homo sapiens] Length = 272 Score = 40.8 bits (94), Expect = 0.002 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 4/52 (7%) Query: 278 CEVSLWSSWGLC---GGHCG-RLGTKSRTRYVRVQPANNGSPCPELEEEAEC 325 CEVS W+ W C G CG + GT++R R + P+ G+ CP E +C Sbjct: 148 CEVSEWNPWSPCTKKGKTCGFKRGTETRVREIIQHPSAKGNLCPPTNETRKC 199 >gi|222446611 R-spondin family, member 2 [Homo sapiens] Length = 243 Score = 40.4 bits (93), Expect = 0.002 Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 4/52 (7%) Query: 278 CEVSLWSSWGLCGGH---CG-RLGTKSRTRYVRVQPANNGSPCPELEEEAEC 325 CEV WS WG C + CG + G ++RTR + +P + CP + E C Sbjct: 145 CEVGHWSEWGTCSRNNRTCGFKWGLETRTRQIVKKPVKDTILCPTIAESRRC 196 >gi|4557391 complement component 8, beta polypeptide preproprotein [Homo sapiens] Length = 591 Score = 38.1 bits (87), Expect = 0.011 Identities = 26/62 (41%), Positives = 33/62 (53%), Gaps = 8/62 (12%) Query: 268 SASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYV-RVQPAN-NGSPCPELEEEAE- 324 S V P+DCE+S WSSW C C K R RY +QP+ +G PC ++E E Sbjct: 55 SVDVTLMPIDCELSSWSSWTTC-DPC----QKKRYRYAYLLQPSQFHGEPCNFSDKEVED 109 Query: 325 CV 326 CV Sbjct: 110 CV 111 Score = 33.1 bits (74), Expect = 0.35 Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 6/44 (13%) Query: 274 TPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYV-RVQPANNGSPC 316 TP+D + + WS+W C G K+R R P N GSPC Sbjct: 542 TPIDGKWNCWSNWSSCSGR-----RKTRQRQCNNPPPQNGGSPC 580 >gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo sapiens] Length = 1584 Score = 38.1 bits (87), Expect = 0.011 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 4/66 (6%) Query: 259 PSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPE 318 P R+ + ++++V P+ WS W LC CGR G + RTR R P G+PC Sbjct: 393 PLREQRLCNNSAV--CPVHGAWDEWSPWSLCSSTCGR-GFRDRTRTCR-PPQFGGNPCEG 448 Query: 319 LEEEAE 324 E++ + Sbjct: 449 PEKQTK 454 Score = 34.7 bits (78), Expect = 0.12 Identities = 20/50 (40%), Positives = 24/50 (48%), Gaps = 2/50 (4%) Query: 282 LWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCP-ELEEEAECVPDNC 330 LWS WG C CG G ++RTR P G C LEE +C + C Sbjct: 266 LWSLWGECTRDCGG-GLQTRTRTCLPAPGVEGGGCEGVLEEGRQCNREAC 314 Score = 32.7 bits (73), Expect = 0.46 Identities = 20/73 (27%), Positives = 30/73 (41%), Gaps = 3/73 (4%) Query: 259 PSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCP- 317 P + + + A P +D + WSSW C C + G + RTR P+ G+ C Sbjct: 449 PEKQTKFCNIALCPGRAVDGNWNEWSSWSACSASCSQ-GRQQRTRECN-GPSYGGAECQG 506 Query: 318 ELEEEAECVPDNC 330 E +C C Sbjct: 507 HWVETRDCFLQQC 519 Score = 31.6 bits (70), Expect = 1.0 Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 3/59 (5%) Query: 273 ETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEE-AECVPDNC 330 + P+D + W+SWG C CG G++ R R V P G+ C ++E +C C Sbjct: 518 QCPVDGKWQAWASWGSCSVTCG-AGSQRRER-VCSGPFFGGAACQGPQDEYRQCGTQRC 574 >gi|145699139 cartilage intermediate layer protein 2 [Homo sapiens] Length = 1156 Score = 37.0 bits (84), Expect = 0.024 Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 5/57 (8%) Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAE-CVPDNC 330 PL+ W WG C G CG G + R R+ P+ G CP EA+ CV C Sbjct: 144 PLEASWGAWGPWGPCSGSCGP-GRRLRRRHC---PSPAGDACPGRPLEAQKCVRPRC 196 >gi|192449445 cartilage intermediate layer protein [Homo sapiens] Length = 1184 Score = 36.2 bits (82), Expect = 0.042 Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 4/51 (7%) Query: 281 SLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAE-CVPDNC 330 S WS W C CG+ G ++RT R+ A S C E EE + C+ +C Sbjct: 153 SPWSPWSKCSAACGQTGVQTRT---RICLAEMVSLCSEASEEGQHCMGQDC 200 >gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens] Length = 1585 Score = 35.4 bits (80), Expect = 0.071 Identities = 19/40 (47%), Positives = 23/40 (57%), Gaps = 4/40 (10%) Query: 283 WSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPC--PELE 320 W SW LC CGR G++SR R V P + G C PEL+ Sbjct: 370 WGSWSLCSRSCGR-GSRSRMR-TCVPPQHGGKACEGPELQ 407 >gi|118572606 hemicentin 1 [Homo sapiens] Length = 5635 Score = 35.0 bits (79), Expect = 0.093 Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 3/52 (5%) Query: 281 SLWSSWGLCGGHCGRLGTKSRTRYV-RVQPANNGSPCPELEEEAE-CVPDNC 330 S W WG C CG+ GT++R R PA GS C E + + C NC Sbjct: 4647 SAWQPWGTCSESCGK-GTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNC 4697 Score = 33.5 bits (75), Expect = 0.27 Identities = 17/44 (38%), Positives = 19/44 (43%), Gaps = 2/44 (4%) Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYV-RVQPANNGSPCP 317 P+D W SW C CG G K+R R P G PCP Sbjct: 4812 PVDGSWGSWHSWSQCSASCGG-GEKTRKRLCDHPVPVKGGRPCP 4854 Score = 33.1 bits (74), Expect = 0.35 Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 2/37 (5%) Query: 281 SLWSSWGLCGGHCGRLGTKSRTRYV-RVQPANNGSPC 316 S WS+W C CG+ G + R+R + PAN G PC Sbjct: 4533 SQWSAWRACSVTCGK-GIQKRSRLCNQPLPANGGKPC 4568 Score = 30.0 bits (66), Expect = 3.0 Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 2/43 (4%) Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGS-PC 316 P+D S WS W C CGR G ++RTR +G PC Sbjct: 4584 PVDGSWSEWSLWEECTRSCGR-GNQTRTRTCNNPSVQHGGRPC 4625 >gi|209977117 unc-5 homolog D [Homo sapiens] Length = 953 Score = 34.7 bits (78), Expect = 0.12 Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 4/58 (6%) Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAE-CVPDNCV 331 P+D +WS W +C C L + T P N G C L +E+E C C+ Sbjct: 306 PVDGSWEVWSEWSVCSPECEHLRIRECT---APPPRNGGKFCEGLSQESENCTDGLCI 360 Score = 28.9 bits (63), Expect = 6.6 Identities = 12/36 (33%), Positives = 14/36 (38%) Query: 281 SLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPC 316 S W+ W C CGR K P N G+ C Sbjct: 256 SSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFC 291 >gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens] Length = 1989 Score = 33.9 bits (76), Expect = 0.21 Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 23/104 (22%) Query: 181 ALDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYY------------- 227 +LD P D+G G + N+ + DT +E +S +PS F+ Sbjct: 510 SLDKQPTDSG---GGIYQYDNYEEVAMDTDSETSSPAPSPVQPPFFSECSLGYFSPAPSL 566 Query: 228 -----PRLKALPPIARVTLVRLRQS--PRAFIPPAPVLPSRDNE 264 P++ +LPP+++ + L S P +PP P LP D E Sbjct: 567 SLPPPPQVSSLPPLSQPYVEGLCVSLEPLPPLPPLPPLPPEDPE 610 >gi|4505737 complement factor properdin precursor [Homo sapiens] Length = 469 Score = 33.1 bits (74), Expect = 0.35 Identities = 15/34 (44%), Positives = 19/34 (55%) Query: 270 SVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTR 303 S+ PL S WS+WGLC CG T++R R Sbjct: 372 SIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQR 405 >gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens] Length = 1522 Score = 33.1 bits (74), Expect = 0.35 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 4/58 (6%) Query: 259 PSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPC 316 P R++ + ++ ++ P+ WS W LC CGR G ++RTR P G PC Sbjct: 329 PLRESRVCNNTAL--CPVHGVWEEWSPWSLCSFTCGR-GQRTRTRSC-TPPQYGGRPC 382 Score = 32.0 bits (71), Expect = 0.78 Identities = 20/57 (35%), Positives = 25/57 (43%), Gaps = 3/57 (5%) Query: 275 PLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPC-PELEEEAECVPDNC 330 P+D + WSSW C C GT+ R+R A+ GS C E EC C Sbjct: 398 PVDGQWQEWSSWSQCSVTCSN-GTQQRSRQC-TAAAHGGSECRGPWAESRECYNPEC 452 >gi|223671861 complement factor properdin precursor [Homo sapiens] Length = 469 Score = 33.1 bits (74), Expect = 0.35 Identities = 15/34 (44%), Positives = 19/34 (55%) Query: 270 SVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTR 303 S+ PL S WS+WGLC CG T++R R Sbjct: 372 SIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQR 405 >gi|4502511 complement component 9 precursor [Homo sapiens] Length = 559 Score = 32.7 bits (73), Expect = 0.46 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 5/69 (7%) Query: 260 SRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPE- 318 S D E+ +S+ + +DC +S WS W C C L R+R + V NG C + Sbjct: 26 SYDPELTESSG-SASHIDCRMSPWSEWSQC-DPC--LRQMFRSRSIEVFGQFNGKRCTDA 81 Query: 319 LEEEAECVP 327 + + +CVP Sbjct: 82 VGDRRQCVP 90 >gi|158187511 T-box 22 isoform 2 [Homo sapiens] Length = 400 Score = 32.7 bits (73), Expect = 0.46 Identities = 39/144 (27%), Positives = 58/144 (40%), Gaps = 9/144 (6%) Query: 176 WREQAALDLYPYDAGTDSGFTFSSP----NFATIPQDTVTEITSSSPSH--PANSFYYPR 229 WR LD + A T SG + SSP A P +++ SP P +S P Sbjct: 180 WRPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPC 239 Query: 230 LKALPPIARVTLVRLRQSPRAFIPPAP-VLPSRDNEIVDSASVPETPLDCEVSLWSSWGL 288 +A P + L + P F P VLP+ + ++S PL EV + SS G+ Sbjct: 240 PEAYLPNVNLPLC-YKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGV 298 Query: 289 CGGHCGRLGTKSRTRYVRVQPANN 312 G S +Y++ + N Sbjct: 299 TNSKSGS-SEDSSDQYLQAPNSTN 321 >gi|158187509 T-box 22 isoform 1 [Homo sapiens] Length = 520 Score = 32.7 bits (73), Expect = 0.46 Identities = 39/144 (27%), Positives = 58/144 (40%), Gaps = 9/144 (6%) Query: 176 WREQAALDLYPYDAGTDSGFTFSSP----NFATIPQDTVTEITSSSPSH--PANSFYYPR 229 WR LD + A T SG + SSP A P +++ SP P +S P Sbjct: 300 WRPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPC 359 Query: 230 LKALPPIARVTLVRLRQSPRAFIPPAP-VLPSRDNEIVDSASVPETPLDCEVSLWSSWGL 288 +A P + L + P F P VLP+ + ++S PL EV + SS G+ Sbjct: 360 PEAYLPNVNLPLC-YKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGV 418 Query: 289 CGGHCGRLGTKSRTRYVRVQPANN 312 G S +Y++ + N Sbjct: 419 TNSKSGS-SEDSSDQYLQAPNSTN 441 >gi|18375603 T-box 22 isoform 1 [Homo sapiens] Length = 520 Score = 32.7 bits (73), Expect = 0.46 Identities = 39/144 (27%), Positives = 58/144 (40%), Gaps = 9/144 (6%) Query: 176 WREQAALDLYPYDAGTDSGFTFSSP----NFATIPQDTVTEITSSSPSH--PANSFYYPR 229 WR LD + A T SG + SSP A P +++ SP P +S P Sbjct: 300 WRPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPC 359 Query: 230 LKALPPIARVTLVRLRQSPRAFIPPAP-VLPSRDNEIVDSASVPETPLDCEVSLWSSWGL 288 +A P + L + P F P VLP+ + ++S PL EV + SS G+ Sbjct: 360 PEAYLPNVNLPLC-YKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGV 418 Query: 289 CGGHCGRLGTKSRTRYVRVQPANN 312 G S +Y++ + N Sbjct: 419 TNSKSGS-SEDSSDQYLQAPNSTN 441 >gi|122937388 MAX gene associated [Homo sapiens] Length = 3114 Score = 32.7 bits (73), Expect = 0.46 Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 18/114 (15%) Query: 213 ITSSSPSHPANSFYYPRLKALPPIARVTLVRLRQSPRAFIP-PAPVLPSRDNEIVDSASV 271 I + S P P+ + L P + L+ +SPR++ P P PV+ D + Sbjct: 1174 IPTPSVIEPMKPLLLPQPEVLSPTVKGKLLTGIKSPRSYTPKPNPVIREEDKD------- 1226 Query: 272 PETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAEC 325 V L+ + C R+ R + + QP+++ SP P +++ C Sbjct: 1227 -------PVYLYFESMMT---CARVRVYERKKEDQRQPSSSSSPSPSFQQQTSC 1270 >gi|16933525 unc5C [Homo sapiens] Length = 931 Score = 32.0 bits (71), Expect = 0.78 Identities = 15/37 (40%), Positives = 19/37 (51%), Gaps = 2/37 (5%) Query: 281 SLWSSWGLCGGHCGRLGTKSRTR-YVRVQPANNGSPC 316 S W+ W +C CGR G + RTR P N G+ C Sbjct: 264 STWTEWSVCNSRCGR-GYQKRTRTCTNPAPLNGGAFC 299 >gi|110611170 ADAM metallopeptidase with thrombospondin type 1 motif, 17 preproprotein [Homo sapiens] Length = 1095 Score = 32.0 bits (71), Expect = 0.78 Identities = 19/66 (28%), Positives = 27/66 (40%), Gaps = 2/66 (3%) Query: 261 RDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELE 320 R E V +PE +D + S W +W +C CG + + P G+ CP Sbjct: 528 RAGECVSKTPIPEH-VDGDWSPWGAWSMCSRTCGTGARFRQRKCDNPPPGPGGTHCPGAS 586 Query: 321 -EEAEC 325 E A C Sbjct: 587 VEHAVC 592 >gi|40317626 thrombospondin 1 precursor [Homo sapiens] Length = 1170 Score = 31.6 bits (70), Expect = 1.0 Identities = 20/52 (38%), Positives = 21/52 (40%), Gaps = 3/52 (5%) Query: 281 SLWSSWGLCGGHCGRLGTKSRTRYVR-VQPANNGSPCP-ELEEEAECVPDNC 330 S WS W C CG G +R R P NG PC E E C D C Sbjct: 439 SHWSPWSSCSVTCGD-GVITRIRLCNSPSPQMNGKPCEGEARETKACKKDAC 489 >gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] Length = 3664 Score = 31.6 bits (70), Expect = 1.0 Identities = 33/131 (25%), Positives = 54/131 (41%), Gaps = 16/131 (12%) Query: 129 VPSGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGDRWREQAALDLYPYD 188 +PS T +S E+ V+ R + V +P P VD R+R + ++ P Sbjct: 2405 IPS-TENSSQEISVEERTPTKASVPPDLPPPPQPAPVDEEPQA---RFRVHSIIESDPV- 2459 Query: 189 AGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYPRLKALPPIARVTLVRLRQSP 248 + P+ +IP T+ +T++ S P S P PP + ++ P Sbjct: 2460 ---------TPPSDPSIPIPTLPSVTAAKLSPPVASGGIPHQS--PPTKVTEWITRQEEP 2508 Query: 249 RAFIPPAPVLP 259 RA P+P LP Sbjct: 2509 RAQSTPSPALP 2519 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.132 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,326,583 Number of Sequences: 37866 Number of extensions: 768851 Number of successful extensions: 2393 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 25 Number of HSP's successfully gapped in prelim test: 54 Number of HSP's that attempted gapping in prelim test: 2261 Number of HSP's gapped (non-prelim): 165 length of query: 331 length of database: 18,247,518 effective HSP length: 103 effective length of query: 228 effective length of database: 14,347,320 effective search space: 3271188960 effective search space used: 3271188960 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.