Search of human proteins with 189217895

Search of human proteins with 189217895

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189217895 KH domain-containing, RNA-binding, signal
transduction-associated protein 2 [Homo sapiens]
         (349 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189217895 KH domain-containing, RNA-binding, signal transduct...   716   0.0  
gi|5730073 KH domain containing, RNA binding, signal transductio...   446   e-125
gi|5730027 KH domain containing, RNA binding, signal transductio...   429   e-120
gi|45827712 quaking homolog, KH domain RNA binding isoform HQK-7...   141   1e-33
gi|45827710 quaking homolog, KH domain RNA binding isoform HQK-7...   141   1e-33
gi|45827708 quaking homolog, KH domain RNA binding isoform HQK-6...   141   1e-33
gi|45827706 quaking homolog, KH domain RNA binding isoform HQK-5...   141   1e-33
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]                 81   2e-15
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 81   2e-15
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 81   2e-15
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    48   1e-05
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    47   2e-05
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    47   2e-05
gi|56699409 RNA binding motif protein, X-linked [Homo sapiens]         47   3e-05
gi|160707881 formin 2 [Homo sapiens]                                   45   1e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni...    45   1e-04
gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]                     44   2e-04
gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]                     44   2e-04
gi|38150007 small nuclear ribonucleoprotein polypeptide B/B' iso...    44   2e-04
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]             44   3e-04
gi|148536848 carboxyl ester lipase precursor [Homo sapiens]            43   4e-04
gi|170016069 zinc finger, CCHC domain containing 2 [Homo sapiens]      43   4e-04
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     42   6e-04
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     42   6e-04
gi|157168329 formin 1 [Homo sapiens]                                   42   8e-04
gi|116292174 fidgetin-like 2 [Homo sapiens]                            42   8e-04
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo...    42   8e-04
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         42   8e-04
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    42   0.001
gi|33356148 formin-like 1 [Homo sapiens]                               42   0.001

>gi|189217895 KH domain-containing, RNA-binding, signal
           transduction-associated protein 2 [Homo sapiens]
          Length = 349

 Score =  716 bits (1848), Expect = 0.0
 Identities = 349/349 (100%), Positives = 349/349 (100%)

Query: 1   MEEEKYLPELMAEKDSLDPSFVHASRLLAEEIEKFQGSDGKKEDEEKKYLDVISNKNIKL 60
           MEEEKYLPELMAEKDSLDPSFVHASRLLAEEIEKFQGSDGKKEDEEKKYLDVISNKNIKL
Sbjct: 1   MEEEKYLPELMAEKDSLDPSFVHASRLLAEEIEKFQGSDGKKEDEEKKYLDVISNKNIKL 60

Query: 61  SERVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRKSG 120
           SERVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRKSG
Sbjct: 61  SERVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRKSG 120

Query: 121 EAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLRELSYLNG 180
           EAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLRELSYLNG
Sbjct: 121 EAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLRELSYLNG 180

Query: 181 SEDSGRGRGIRGRGIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVAR 240
           SEDSGRGRGIRGRGIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVAR
Sbjct: 181 SEDSGRGRGIRGRGIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVAR 240

Query: 241 GVPTPRARGAPTVPGYRAPPPPAHEAYEEYGYDDGYGGEYDDQTYETYDNSYATQTQSVP 300
           GVPTPRARGAPTVPGYRAPPPPAHEAYEEYGYDDGYGGEYDDQTYETYDNSYATQTQSVP
Sbjct: 241 GVPTPRARGAPTVPGYRAPPPPAHEAYEEYGYDDGYGGEYDDQTYETYDNSYATQTQSVP 300

Query: 301 EYYDYGHGVSEDAYDSYAPEEWATTRSSLKAPPQRSARGGYREHPYGRY 349
           EYYDYGHGVSEDAYDSYAPEEWATTRSSLKAPPQRSARGGYREHPYGRY
Sbjct: 301 EYYDYGHGVSEDAYDSYAPEEWATTRSSLKAPPQRSARGGYREHPYGRY 349


>gi|5730073 KH domain containing, RNA binding, signal transduction
           associated 3 [Homo sapiens]
          Length = 346

 Score =  446 bits (1148), Expect = e-125
 Identities = 234/355 (65%), Positives = 271/355 (76%), Gaps = 18/355 (5%)

Query: 3   EEKYLPELMAEKDSLDPSFVHASRLLAEEIEKFQGSDGKKEDEEKKYLDVISNKNIKLSE 62
           EEKYLPELMAEKDSLDPSF HA RL+ +EIEKFQ  +GK   +E+KY+DV+ NKN+KL +
Sbjct: 2   EEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGK---DEEKYIDVVINKNMKLGQ 58

Query: 63  RVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRKSGEA 122
           +VLIPVKQ+PKFNFVGKLLGPRGNSLKRLQEET  KMSILGKGSMRDKAKEEELRKSGEA
Sbjct: 59  KVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEA 118

Query: 123 KYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLRELSYLNGSE 182
           KY HL+D+LHVLIEVFAPP EAY+RM HALEEIKKFL+PDYNDEIRQ QL+EL+YLNG  
Sbjct: 119 KYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGS 178

Query: 183 DSGRGRGIRG----RGIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPV-PP 237
           ++     +RG    R   +   A +RGRGG    P     GV+ PRG+   RG L    P
Sbjct: 179 ENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPV----GVVVPRGTPTPRGVLSTRGP 234

Query: 238 VA--RGVPTPRARGAPTVPGYR-APPPPAHEAYEEYGYDDGYGGEYDDQTYETYDNSYAT 294
           V+  RG+ TPRARG P   GYR  PPPP  E Y EY YDDGYG  YD+Q+Y++YDNSY+T
Sbjct: 235 VSRGRGLLTPRARGVPPT-GYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYST 293

Query: 295 QTQSVPEYYDYGHGVSEDAYDSYAPEEWATTRSSLKAPPQRSARGGYREHPYGRY 349
             QS  +YYDYGHG+SE+ YDSY  EEW  T S  KAP  R+A+G YR+ PYGRY
Sbjct: 294 PAQSGADYYDYGHGLSEETYDSYGQEEW--TNSRHKAPSARTAKGVYRDQPYGRY 346


>gi|5730027 KH domain containing, RNA binding, signal transduction
           associated 1 [Homo sapiens]
          Length = 443

 Score =  429 bits (1102), Expect = e-120
 Identities = 223/355 (62%), Positives = 261/355 (73%), Gaps = 19/355 (5%)

Query: 3   EEKYLPELMAEKDSLDPSFVHASRLLAEEIEKFQGSDGKKEDEEKKYLDVISNKNIKLSE 62
           E KYLPELMAEKDSLDPSF HA +LL  EIEK Q  D KK+DEE  YLD+ S+KN+KL E
Sbjct: 100 ENKYLPELMAEKDSLDPSFTHAMQLLTAEIEKIQKGDSKKDDEEN-YLDLFSHKNMKLKE 158

Query: 63  RVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRKSGEA 122
           RVLIPVKQYPKFNFVGK+LGP+GN++KRLQEETGAK+S+LGKGSMRDKAKEEELRK G+ 
Sbjct: 159 RVLIPVKQYPKFNFVGKILGPQGNTIKRLQEETGAKISVLGKGSMRDKAKEEELRKGGDP 218

Query: 123 KYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLRELSYLNGSE 182
           KYAHL+ +LHV IEVF PP EAY+ M+HA+EE+KKFLVPD  D+I QEQ  ELSYLNG  
Sbjct: 219 KYAHLNMDLHVFIEVFGPPCEAYALMAHAMEEVKKFLVPDMMDDICQEQFLELSYLNGVP 278

Query: 183 DSGRGRGIRGRGIRIAPTAPSRGRGGAIPPP------PPPGRGVLTPRGSTVTRGALPVP 236
           +  RGRG+  RG   AP  P   RG  + PP        P RG +T RG+TVTRG +P P
Sbjct: 279 EPSRGRGVPVRGRGAAPPPPPVPRGRGVGPPRGALVRGTPVRGAIT-RGATVTRG-VPPP 336

Query: 237 PVARGVPTPRAR--GAPTVPGYRAPPPPAHEAYEEYGYDDGYGGEYDDQTYETYDNSYAT 294
           P  RG P PRAR  G   +P    PPPPA E YEEYGYDD Y     +Q+YE Y+  Y +
Sbjct: 337 PTVRGAPAPRARTAGIQRIP---LPPPPAPETYEEYGYDDTYA----EQSYEGYE-GYYS 388

Query: 295 QTQSVPEYYDYGHGVSEDAYDSYAPEEWATTRSSLKAPPQRSARGGYREHPYGRY 349
           Q+Q   EYYDYGHG  +D+Y++Y  ++W  TR SLKAPP R  +G YREHPYGRY
Sbjct: 389 QSQGDSEYYDYGHGEVQDSYEAYGQDDWNGTRPSLKAPPARPVKGAYREHPYGRY 443


>gi|45827712 quaking homolog, KH domain RNA binding isoform HQK-7B
           [Homo sapiens]
          Length = 319

 Score =  141 bits (355), Expect = 1e-33
 Identities = 103/287 (35%), Positives = 148/287 (51%), Gaps = 33/287 (11%)

Query: 6   YLPELMAEKDSLD--PSFV----HASRLLAEEIEKFQGS------DGKKEDEEKKYLDVI 53
           YL +LM +K  +   P+F     H  RLL EEI + +        +G  E    +  D +
Sbjct: 17  YLMQLMNDKKLMSSLPNFCGIFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELPDAV 76

Query: 54  SNKNIKLSERVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKE 113
               ++L E++ +PVK+YP FNFVG++LGPRG + K+L+ ETG K+ + GKGSMRDK KE
Sbjct: 77  G-PIVQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKE 135

Query: 114 EELRKSGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVP--DYNDEIRQEQ 171
           E+ R  G+  + HL+++LHVLI V      A  ++  A+EE+KK LVP  +  D +++ Q
Sbjct: 136 EQNR--GKPNWEHLNEDLHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGEDSLKKMQ 193

Query: 172 LRELSYLNGSEDSGRGRGIRGRGI--RIAPTAPSRGR--GGAIPPPPPPGRGVLTPRGST 227
           L EL+ LNG+    R   I+   +   +A TA +  R   G  P  PP      TP G T
Sbjct: 194 LMELAILNGTY---RDANIKSPALAFSLAATAQAAPRIITGPAPVLPPAALRTPTPAGPT 250

Query: 228 VTR--GALPVPPVARGVPTPRARGAPTVPGYRAPPPPAHEAYEEYGY 272
           +      +    +  G P P A   P       P P A   Y  Y Y
Sbjct: 251 IMPLIRQIQTAVMPNGTPHPTAAIVP-------PGPEAGLIYTPYEY 290


>gi|45827710 quaking homolog, KH domain RNA binding isoform HQK-7
           [Homo sapiens]
          Length = 325

 Score =  141 bits (355), Expect = 1e-33
 Identities = 103/287 (35%), Positives = 148/287 (51%), Gaps = 33/287 (11%)

Query: 6   YLPELMAEKDSLD--PSFV----HASRLLAEEIEKFQGS------DGKKEDEEKKYLDVI 53
           YL +LM +K  +   P+F     H  RLL EEI + +        +G  E    +  D +
Sbjct: 17  YLMQLMNDKKLMSSLPNFCGIFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELPDAV 76

Query: 54  SNKNIKLSERVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKE 113
               ++L E++ +PVK+YP FNFVG++LGPRG + K+L+ ETG K+ + GKGSMRDK KE
Sbjct: 77  G-PIVQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKE 135

Query: 114 EELRKSGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVP--DYNDEIRQEQ 171
           E+ R  G+  + HL+++LHVLI V      A  ++  A+EE+KK LVP  +  D +++ Q
Sbjct: 136 EQNR--GKPNWEHLNEDLHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGEDSLKKMQ 193

Query: 172 LRELSYLNGSEDSGRGRGIRGRGI--RIAPTAPSRGR--GGAIPPPPPPGRGVLTPRGST 227
           L EL+ LNG+    R   I+   +   +A TA +  R   G  P  PP      TP G T
Sbjct: 194 LMELAILNGTY---RDANIKSPALAFSLAATAQAAPRIITGPAPVLPPAALRTPTPAGPT 250

Query: 228 VTR--GALPVPPVARGVPTPRARGAPTVPGYRAPPPPAHEAYEEYGY 272
           +      +    +  G P P A   P       P P A   Y  Y Y
Sbjct: 251 IMPLIRQIQTAVMPNGTPHPTAAIVP-------PGPEAGLIYTPYEY 290


>gi|45827708 quaking homolog, KH domain RNA binding isoform HQK-6
           [Homo sapiens]
          Length = 319

 Score =  141 bits (355), Expect = 1e-33
 Identities = 103/287 (35%), Positives = 148/287 (51%), Gaps = 33/287 (11%)

Query: 6   YLPELMAEKDSLD--PSFV----HASRLLAEEIEKFQGS------DGKKEDEEKKYLDVI 53
           YL +LM +K  +   P+F     H  RLL EEI + +        +G  E    +  D +
Sbjct: 17  YLMQLMNDKKLMSSLPNFCGIFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELPDAV 76

Query: 54  SNKNIKLSERVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKE 113
               ++L E++ +PVK+YP FNFVG++LGPRG + K+L+ ETG K+ + GKGSMRDK KE
Sbjct: 77  G-PIVQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKE 135

Query: 114 EELRKSGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVP--DYNDEIRQEQ 171
           E+ R  G+  + HL+++LHVLI V      A  ++  A+EE+KK LVP  +  D +++ Q
Sbjct: 136 EQNR--GKPNWEHLNEDLHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGEDSLKKMQ 193

Query: 172 LRELSYLNGSEDSGRGRGIRGRGI--RIAPTAPSRGR--GGAIPPPPPPGRGVLTPRGST 227
           L EL+ LNG+    R   I+   +   +A TA +  R   G  P  PP      TP G T
Sbjct: 194 LMELAILNGTY---RDANIKSPALAFSLAATAQAAPRIITGPAPVLPPAALRTPTPAGPT 250

Query: 228 VTR--GALPVPPVARGVPTPRARGAPTVPGYRAPPPPAHEAYEEYGY 272
           +      +    +  G P P A   P       P P A   Y  Y Y
Sbjct: 251 IMPLIRQIQTAVMPNGTPHPTAAIVP-------PGPEAGLIYTPYEY 290


>gi|45827706 quaking homolog, KH domain RNA binding isoform HQK-5
           [Homo sapiens]
          Length = 341

 Score =  141 bits (355), Expect = 1e-33
 Identities = 103/287 (35%), Positives = 148/287 (51%), Gaps = 33/287 (11%)

Query: 6   YLPELMAEKDSLD--PSFV----HASRLLAEEIEKFQGS------DGKKEDEEKKYLDVI 53
           YL +LM +K  +   P+F     H  RLL EEI + +        +G  E    +  D +
Sbjct: 17  YLMQLMNDKKLMSSLPNFCGIFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELPDAV 76

Query: 54  SNKNIKLSERVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKE 113
               ++L E++ +PVK+YP FNFVG++LGPRG + K+L+ ETG K+ + GKGSMRDK KE
Sbjct: 77  G-PIVQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKE 135

Query: 114 EELRKSGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVP--DYNDEIRQEQ 171
           E+ R  G+  + HL+++LHVLI V      A  ++  A+EE+KK LVP  +  D +++ Q
Sbjct: 136 EQNR--GKPNWEHLNEDLHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGEDSLKKMQ 193

Query: 172 LRELSYLNGSEDSGRGRGIRGRGI--RIAPTAPSRGR--GGAIPPPPPPGRGVLTPRGST 227
           L EL+ LNG+    R   I+   +   +A TA +  R   G  P  PP      TP G T
Sbjct: 194 LMELAILNGTY---RDANIKSPALAFSLAATAQAAPRIITGPAPVLPPAALRTPTPAGPT 250

Query: 228 VTR--GALPVPPVARGVPTPRARGAPTVPGYRAPPPPAHEAYEEYGY 272
           +      +    +  G P P A   P       P P A   Y  Y Y
Sbjct: 251 IMPLIRQIQTAVMPNGTPHPTAAIVP-------PGPEAGLIYTPYEY 290


>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
          Length = 548

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 48/135 (35%), Positives = 78/135 (57%), Gaps = 16/135 (11%)

Query: 59  KLSERVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRK 118
           ++S++V+IP  +YP+ NFVG L+GPRGN+LK +++E  AK+ I GKGS+    KE ++ +
Sbjct: 135 RVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSV----KEGKVGR 190

Query: 119 SGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFL-----VPDYNDEIRQEQLR 173
                     + LH L+            +  A+E+I+  L      P+  +++R+ QLR
Sbjct: 191 KDGQMLPGEDEPLHALV-----TANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLR 245

Query: 174 ELSYLNGS--EDSGR 186
           EL+ LNG+  ED  R
Sbjct: 246 ELARLNGTLREDDNR 260



 Score = 30.0 bits (66), Expect = 3.2
 Identities = 24/74 (32%), Positives = 30/74 (40%), Gaps = 27/74 (36%)

Query: 211 PPPPPPGRGV----------------LTPRGSTVTR-----GALPVPPVARGVPTPRARG 249
           PPPPP  +G                  TP GS V R     G +P PP+   +P P    
Sbjct: 427 PPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGM-MPPP---- 481

Query: 250 APTVPGYRAPPPPA 263
            P  P  + PPPP+
Sbjct: 482 -PPPPSGQPPPPPS 494


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 48/135 (35%), Positives = 78/135 (57%), Gaps = 16/135 (11%)

Query: 59  KLSERVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRK 118
           ++S++V+IP  +YP+ NFVG L+GPRGN+LK +++E  AK+ I GKGS+    KE ++ +
Sbjct: 135 RVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSV----KEGKVGR 190

Query: 119 SGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFL-----VPDYNDEIRQEQLR 173
                     + LH L+            +  A+E+I+  L      P+  +++R+ QLR
Sbjct: 191 KDGQMLPGEDEPLHALV-----TANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLR 245

Query: 174 ELSYLNGS--EDSGR 186
           EL+ LNG+  ED  R
Sbjct: 246 ELARLNGTLREDDNR 260



 Score = 30.0 bits (66), Expect = 3.2
 Identities = 24/74 (32%), Positives = 30/74 (40%), Gaps = 27/74 (36%)

Query: 211 PPPPPPGRGV----------------LTPRGSTVTR-----GALPVPPVARGVPTPRARG 249
           PPPPP  +G                  TP GS V R     G +P PP+   +P P    
Sbjct: 427 PPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGM-MPPP---- 481

Query: 250 APTVPGYRAPPPPA 263
            P  P  + PPPP+
Sbjct: 482 -PPPPSGQPPPPPS 494



 Score = 28.9 bits (63), Expect = 7.2
 Identities = 25/92 (27%), Positives = 34/92 (36%), Gaps = 28/92 (30%)

Query: 199 PTAPSRGRGGAIPPPPPPGRGVL--TP-------RGSTVTRGALPVPP-------VARGV 242
           P  P + +    PPPPPP   +   TP         +T + G   +PP        A   
Sbjct: 496 PLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASP 555

Query: 243 PTPRARGAPTV------------PGYRAPPPP 262
             P+ +G PT+            PG   PPPP
Sbjct: 556 GAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPP 587


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 48/135 (35%), Positives = 78/135 (57%), Gaps = 16/135 (11%)

Query: 59  KLSERVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRK 118
           ++S++V+IP  +YP+ NFVG L+GPRGN+LK +++E  AK+ I GKGS+    KE ++ +
Sbjct: 135 RVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSV----KEGKVGR 190

Query: 119 SGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFL-----VPDYNDEIRQEQLR 173
                     + LH L+            +  A+E+I+  L      P+  +++R+ QLR
Sbjct: 191 KDGQMLPGEDEPLHALV-----TANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLR 245

Query: 174 ELSYLNGS--EDSGR 186
           EL+ LNG+  ED  R
Sbjct: 246 ELARLNGTLREDDNR 260



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 22/59 (37%), Positives = 24/59 (40%), Gaps = 10/59 (16%)

Query: 208 GAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVP----TPRARGAPTVPGYRAPPPP 262
           GA PPPPPP      P GS     A P PP     P    T    G   +P +  PP P
Sbjct: 580 GAPPPPPPP------PPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAP 632



 Score = 30.0 bits (66), Expect = 3.2
 Identities = 24/74 (32%), Positives = 30/74 (40%), Gaps = 27/74 (36%)

Query: 211 PPPPPPGRGV----------------LTPRGSTVTR-----GALPVPPVARGVPTPRARG 249
           PPPPP  +G                  TP GS V R     G +P PP+   +P P    
Sbjct: 427 PPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGM-MPPP---- 481

Query: 250 APTVPGYRAPPPPA 263
            P  P  + PPPP+
Sbjct: 482 -PPPPSGQPPPPPS 494



 Score = 28.9 bits (63), Expect = 7.2
 Identities = 25/92 (27%), Positives = 34/92 (36%), Gaps = 28/92 (30%)

Query: 199 PTAPSRGRGGAIPPPPPPGRGVL--TP-------RGSTVTRGALPVPP-------VARGV 242
           P  P + +    PPPPPP   +   TP         +T + G   +PP        A   
Sbjct: 496 PLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASP 555

Query: 243 PTPRARGAPTV------------PGYRAPPPP 262
             P+ +G PT+            PG   PPPP
Sbjct: 556 GAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPP 587


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 32/92 (34%), Positives = 36/92 (39%), Gaps = 15/92 (16%)

Query: 182 EDSGRGRGIRGRGIRIAPTAPSRGRGGAIPPPPPP-----------GRGVLTPRGSTVTR 230
           E +G    ++    R AP  P   RGG  PPPPPP           GRG   P  S    
Sbjct: 260 EKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPT 319

Query: 231 GALPVPPVARGVPTPRARGAPTVPGYRAPPPP 262
            A P PP +R    P     P  P    PPPP
Sbjct: 320 AAPPPPPPSR----PSVAVPPPPPNRMYPPPP 347



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 25/71 (35%), Positives = 26/71 (36%), Gaps = 9/71 (12%)

Query: 206 RGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTV---------PGY 256
           R  A PPPPP   G   P       G  P P   RG P P    APT          P  
Sbjct: 273 RRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSV 332

Query: 257 RAPPPPAHEAY 267
             PPPP +  Y
Sbjct: 333 AVPPPPPNRMY 343



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 29/84 (34%), Positives = 30/84 (35%), Gaps = 7/84 (8%)

Query: 186 RGRGIR----GRGIRIAPTAPSRGRGGAIPPPPPPGRGVLTP---RGSTVTRGALPVPPV 238
           RGRG       R    AP  P   R     PPPPP R    P     S+   G  P PP 
Sbjct: 305 RGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPS 364

Query: 239 ARGVPTPRARGAPTVPGYRAPPPP 262
             GV        P  P    PPPP
Sbjct: 365 VLGVGPVAPPPPPPPPPPPGPPPP 388



 Score = 30.0 bits (66), Expect = 3.2
 Identities = 22/63 (34%), Positives = 26/63 (41%), Gaps = 6/63 (9%)

Query: 199 PTAPSRGRGGAIPPPPPP---GRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPG 255
           P  PS    G  PPPPPP   G G + P          P PP   G+P+      PT  G
Sbjct: 348 PALPSSAPSG--PPPPPPSVLGVGPVAPPPPPPPPPP-PGPPPPPGLPSDGDHQVPTTAG 404

Query: 256 YRA 258
            +A
Sbjct: 405 NKA 407


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 34/98 (34%), Positives = 40/98 (40%), Gaps = 22/98 (22%)

Query: 199 PTAPSRGRGGAIPPPP----------PPGRGVLTPRGSTVTRG--------ALPVPPVAR 240
           P  PS GR G +PPPP          PPGR    P    V+R         A P  P   
Sbjct: 346 PPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRS 405

Query: 241 GVPTPRARGAPTVPGYR----APPPPAHEAYEEYGYDD 274
           GV +PR+   P +P  R    APPPP        G+ D
Sbjct: 406 GVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQD 443



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 5/64 (7%)

Query: 199 PTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPGYRA 258
           P  PSR      PPPPPP          ++ R A+P PP     P   +   P+      
Sbjct: 253 PPTPSRALDDKPPPPPPP-----VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAP 307

Query: 259 PPPP 262
           PPPP
Sbjct: 308 PPPP 311



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 30/84 (35%), Positives = 35/84 (41%), Gaps = 12/84 (14%)

Query: 181 SEDSGRGR-GIRGRGIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVA 239
           S  SG GR  +   G R  P  P R R   +PPP P         GS       PVP   
Sbjct: 142 SPPSGPGRFPVPSPGHRSGPPEPQRNR---MPPPRPDV-------GSKPDSIPPPVPSTP 191

Query: 240 RGVPT-PRARGAPTVPGYRAPPPP 262
           R + + P  RG+P VPG    P P
Sbjct: 192 RPIQSSPHNRGSPPVPGGPRQPSP 215



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 27/92 (29%), Positives = 28/92 (30%), Gaps = 30/92 (32%)

Query: 199 PTAPSRGRGGAIPPPPP----PGRGVLTPRG------------------------STVTR 230
           P+ P        PPPPP    PG   L P                          S    
Sbjct: 295 PSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRS 354

Query: 231 GALPVPPVARGVPTPRARGAPTVPGYRAPPPP 262
           G LP PP  R  P P  R  P   G   PPPP
Sbjct: 355 GPLPPPPSER--PPPPVRDPPGRSGPLPPPPP 384



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 24/87 (27%), Positives = 30/87 (34%), Gaps = 18/87 (20%)

Query: 193 RGIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGAL----------PVPPVARGV 242
           RG    P  P +   G  PPP P  RG     GS + +  L          P+PP     
Sbjct: 201 RGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGS-IRQSPLSSSSPFSNRPPLPPTPSRA 259

Query: 243 -------PTPRARGAPTVPGYRAPPPP 262
                  P P     P++     PPPP
Sbjct: 260 LDDKPPPPPPPVGNRPSIHREAVPPPP 286


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 34/98 (34%), Positives = 40/98 (40%), Gaps = 22/98 (22%)

Query: 199 PTAPSRGRGGAIPPPP----------PPGRGVLTPRGSTVTRG--------ALPVPPVAR 240
           P  PS GR G +PPPP          PPGR    P    V+R         A P  P   
Sbjct: 346 PPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRS 405

Query: 241 GVPTPRARGAPTVPGYR----APPPPAHEAYEEYGYDD 274
           GV +PR+   P +P  R    APPPP        G+ D
Sbjct: 406 GVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQD 443



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 5/64 (7%)

Query: 199 PTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPGYRA 258
           P  PSR      PPPPPP          ++ R A+P PP     P   +   P+      
Sbjct: 253 PPTPSRALDDKPPPPPPP-----VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAP 307

Query: 259 PPPP 262
           PPPP
Sbjct: 308 PPPP 311



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 30/84 (35%), Positives = 35/84 (41%), Gaps = 12/84 (14%)

Query: 181 SEDSGRGR-GIRGRGIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVA 239
           S  SG GR  +   G R  P  P R R   +PPP P         GS       PVP   
Sbjct: 142 SPPSGPGRFPVPSPGHRSGPPEPQRNR---MPPPRPDV-------GSKPDSIPPPVPSTP 191

Query: 240 RGVPT-PRARGAPTVPGYRAPPPP 262
           R + + P  RG+P VPG    P P
Sbjct: 192 RPIQSSPHNRGSPPVPGGPRQPSP 215



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 27/92 (29%), Positives = 28/92 (30%), Gaps = 30/92 (32%)

Query: 199 PTAPSRGRGGAIPPPPP----PGRGVLTPRG------------------------STVTR 230
           P+ P        PPPPP    PG   L P                          S    
Sbjct: 295 PSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRS 354

Query: 231 GALPVPPVARGVPTPRARGAPTVPGYRAPPPP 262
           G LP PP  R  P P  R  P   G   PPPP
Sbjct: 355 GPLPPPPSER--PPPPVRDPPGRSGPLPPPPP 384



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 24/87 (27%), Positives = 30/87 (34%), Gaps = 18/87 (20%)

Query: 193 RGIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGAL----------PVPPVARGV 242
           RG    P  P +   G  PPP P  RG     GS + +  L          P+PP     
Sbjct: 201 RGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGS-IRQSPLSSSSPFSNRPPLPPTPSRA 259

Query: 243 -------PTPRARGAPTVPGYRAPPPP 262
                  P P     P++     PPPP
Sbjct: 260 LDDKPPPPPPPVGNRPSIHREAVPPPP 286


>gi|56699409 RNA binding motif protein, X-linked [Homo sapiens]
          Length = 391

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 55/189 (29%), Positives = 71/189 (37%), Gaps = 61/189 (32%)

Query: 187 GRGIRGRGIRIAP-TAPSRGRGGAIPPPPP----PGRGVLTPRGST-------------- 227
           G+ + G+ I++   T PS   G   PPPPP    P RG+   RG +              
Sbjct: 71  GKSLDGKAIKVEQATKPSFESGRRGPPPPPRSRGPPRGLRGGRGGSGGTRGPPSRGGHMD 130

Query: 228 -----------VTRGALPV---PPVARGVPTPRARGAPTVP-------GYRAP------- 259
                       +RG LPV   PP   G P P+ R AP+ P       G RAP       
Sbjct: 131 DGGYSMNFNMSSSRGPLPVKRGPPPRSGGPPPK-RSAPSGPVRSSSGMGGRAPVSRGRDS 189

Query: 260 --------PPPAHEAYEEYGYDDGYGGEYDDQTYETYDNSYATQTQSVPE----YYDYGH 307
                   P P+         DDGY  + D  +   Y +S  T+  + P     Y DYGH
Sbjct: 190 YGGPPRREPLPSRRDVYLSPRDDGYSTK-DSYSSRDYPSSRDTRDYAPPPRDYTYRDYGH 248

Query: 308 GVSEDAYDS 316
             S D Y S
Sbjct: 249 SSSRDDYPS 257


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 19/72 (26%)

Query: 193 RGIRIAPTAPSRGRGGAIPPPPP-PGRGVLTPRGSTVTRGALPVPPV-ARGVPTPRARGA 250
           +G  + P  P    G  IPPPPP PG G+            LP+PP+   G+P P     
Sbjct: 903 QGTEMLPPPPPPLPGAGIPPPPPLPGAGI------------LPLPPLPGAGIPPP----- 945

Query: 251 PTVPGYRAPPPP 262
           P +PG   PPPP
Sbjct: 946 PPLPGAAIPPPP 957



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 24/58 (41%), Positives = 31/58 (53%), Gaps = 10/58 (17%)

Query: 208 GAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARG---VPTPRARGAPTVPGYRAPPPP 262
           G +PPPPPP  G+  P   T+   A+P PP  +G   +P P     P +PG   PPPP
Sbjct: 874 GMVPPPPPPLPGMTVP---TLPSTAIPQPPPLQGTEMLPPP----PPPLPGAGIPPPP 924



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 28/79 (35%), Positives = 33/79 (41%), Gaps = 15/79 (18%)

Query: 194 GIRIAPTAPSRGRG--------GAIPPPPPPGRGVLTPRGSTVTRGALPVPP--VARGVP 243
           G  I P  P  G G        GA  PPPPP  G   P    +    +P+PP     G+P
Sbjct: 917 GAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIP 976

Query: 244 TPRARGAPTVPGYRAPPPP 262
            P     P +PG   PPPP
Sbjct: 977 PP-----PPLPGAGIPPPP 990



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 27/73 (36%), Positives = 32/73 (43%), Gaps = 12/73 (16%)

Query: 192  GRGIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPP--VARGVPTPRARG 249
            G GI + P  P     GA  PPPPP  G   P    +    +P PP     G+P P    
Sbjct: 961  GAGIPLPPPLP-----GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP---- 1011

Query: 250  APTVPGYRAPPPP 262
             P +PG   PPPP
Sbjct: 1012 -PPLPGAGIPPPP 1023



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 29/79 (36%), Positives = 33/79 (41%), Gaps = 15/79 (18%)

Query: 194  GIRIAPTAPSRGRG--------GAIPPPPPPGRGVLTPRGSTVTRGALPVPP--VARGVP 243
            G  I P  P  G G        GA  PPPPP  GV  P    +    +P PP     G+P
Sbjct: 1071 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIP 1130

Query: 244  TPRARGAPTVPGYRAPPPP 262
             P     P +PG   PPPP
Sbjct: 1131 PP-----PPLPGAGIPPPP 1144



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 28/79 (35%), Positives = 32/79 (40%), Gaps = 15/79 (18%)

Query: 194  GIRIAPTAPSRGRG--------GAIPPPPPPGRGVLTPRGSTVTRGALPVPP--VARGVP 243
            G  I P  P  G G        GA  PPPPP  G   P    +    +P PP     G+P
Sbjct: 928  GAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIP 987

Query: 244  TPRARGAPTVPGYRAPPPP 262
             P     P +PG   PPPP
Sbjct: 988  PP-----PPLPGAGIPPPP 1001



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 31/85 (36%), Positives = 34/85 (40%), Gaps = 16/85 (18%)

Query: 194  GIRIAPTAPSRGRG--------GAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGV--- 242
            G  I P  P  G G        GA  PPPPP  G   P    +    +P PP   GV   
Sbjct: 1049 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIP 1108

Query: 243  PTPRARGA-----PTVPGYRAPPPP 262
            P P   GA     P +PG   PPPP
Sbjct: 1109 PPPPLPGAGIPPPPPLPGAGIPPPP 1133



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 28/71 (39%), Positives = 33/71 (46%), Gaps = 10/71 (14%)

Query: 194  GIRIAPTAPSRGRGGAIPPPPPPGRGV-LTPRGSTVTRGALPVPPVAR-GVPTPRARGAP 251
            G+ I P  P  G G    PPPPP  G  + P       G  P PP+ R G+P P     P
Sbjct: 1104 GVGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPP-----P 1155

Query: 252  TVPGYRAPPPP 262
             +PG   PPPP
Sbjct: 1156 PLPGAGIPPPP 1166



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 28/79 (35%), Positives = 32/79 (40%), Gaps = 15/79 (18%)

Query: 194  GIRIAPTAPSRGRG--------GAIPPPPPPGRGVLTPRGSTVTRGALPVPP--VARGVP 243
            G  I P  P  G G        GA  PPPPP  G   P    +    +P PP     G+P
Sbjct: 1038 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1097

Query: 244  TPRARGAPTVPGYRAPPPP 262
             P     P +PG   PPPP
Sbjct: 1098 PP-----PPLPGVGIPPPP 1111



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 27/70 (38%), Positives = 30/70 (42%), Gaps = 4/70 (5%)

Query: 194  GIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAP-T 252
            G  I P  P  G G    PPPPP  GV  P    +    +P PP   G+  P A   P  
Sbjct: 1170 GAGIPPPPPLPGVG---IPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLP 1226

Query: 253  VPGYRAPPPP 262
             PG   PPPP
Sbjct: 1227 PPGTGIPPPP 1236



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 28/79 (35%), Positives = 32/79 (40%), Gaps = 15/79 (18%)

Query: 194  GIRIAPTAPSRGRG--------GAIPPPPPPGRGVLTPRGSTVTRGALPVPP--VARGVP 243
            G  I P  P  G G        GA  PPPPP  G   P    +    +P PP     G+P
Sbjct: 972  GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1031

Query: 244  TPRARGAPTVPGYRAPPPP 262
             P     P +PG   PPPP
Sbjct: 1032 PP-----PPLPGAGIPPPP 1045



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 28/79 (35%), Positives = 32/79 (40%), Gaps = 15/79 (18%)

Query: 194  GIRIAPTAPSRGRG--------GAIPPPPPPGRGVLTPRGSTVTRGALPVPP--VARGVP 243
            G  I P  P  G G        GA  PPPPP  G   P    +    +P PP     G+P
Sbjct: 983  GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1042

Query: 244  TPRARGAPTVPGYRAPPPP 262
             P     P +PG   PPPP
Sbjct: 1043 PP-----PPLPGAGIPPPP 1056



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 28/79 (35%), Positives = 32/79 (40%), Gaps = 15/79 (18%)

Query: 194  GIRIAPTAPSRGRG--------GAIPPPPPPGRGVLTPRGSTVTRGALPVPP--VARGVP 243
            G  I P  P  G G        GA  PPPPP  G   P    +    +P PP     G+P
Sbjct: 994  GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1053

Query: 244  TPRARGAPTVPGYRAPPPP 262
             P     P +PG   PPPP
Sbjct: 1054 PP-----PPLPGAGIPPPP 1067



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 28/79 (35%), Positives = 32/79 (40%), Gaps = 15/79 (18%)

Query: 194  GIRIAPTAPSRGRG--------GAIPPPPPPGRGVLTPRGSTVTRGALPVPP--VARGVP 243
            G  I P  P  G G        GA  PPPPP  G   P    +    +P PP     G+P
Sbjct: 1005 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1064

Query: 244  TPRARGAPTVPGYRAPPPP 262
             P     P +PG   PPPP
Sbjct: 1065 PP-----PPLPGAGIPPPP 1078



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 27/77 (35%), Positives = 30/77 (38%), Gaps = 11/77 (14%)

Query: 194  GIRIAPTAPSRGRGGAIPPP--------PPPGRGVLTPRGSTVTRGALPVPPVARGVPTP 245
            G  I P  P  G G   PPP        PPP  G   P    +    +P PP   GV  P
Sbjct: 1126 GAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIP 1185

Query: 246  RARGAPTVPGYRAPPPP 262
                 P +PG   PPPP
Sbjct: 1186 ---PPPPLPGVGIPPPP 1199



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 25/68 (36%), Positives = 29/68 (42%), Gaps = 6/68 (8%)

Query: 195  IRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVP 254
            + I P  P  G G    PPPPP  G   P    +    +P PP   GV  P     P +P
Sbjct: 1149 VGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIP---PPPPLP 1202

Query: 255  GYRAPPPP 262
            G   PPPP
Sbjct: 1203 GAGIPPPP 1210



 Score = 32.3 bits (72), Expect = 0.65
 Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 17/78 (21%)

Query: 192  GRGIRIAPTAPSRGRGGA-IPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGA 250
            G GI   P  P  G   A  PP PPPG G+  P          P+ PV+ G P     G+
Sbjct: 1203 GAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPP----------PLLPVS-GPPLLPQVGS 1251

Query: 251  PTVP-----GYRAPPPPA 263
             T+P     G+  PP P+
Sbjct: 1252 STLPTPQVCGFLPPPLPS 1269



 Score = 32.0 bits (71), Expect = 0.85
 Identities = 23/60 (38%), Positives = 25/60 (41%), Gaps = 5/60 (8%)

Query: 192  GRGIRIAPTAPSRGRGGAIPPPP--PPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARG 249
            G GI  AP  P    G  IPPPP  P     L P+   V    LP P V   +P P   G
Sbjct: 1214 GMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQ---VGSSTLPTPQVCGFLPPPLPSG 1270


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 25/64 (39%), Positives = 31/64 (48%), Gaps = 6/64 (9%)

Query: 198  APTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPGYR 257
            APT P+     A PP P  G    +P+G+  T  A P  P   G+ TP  +GAPT P   
Sbjct: 1171 APTTPA-----ATPPSPKGGLATPSPKGAPTTPAATPPSPKG-GLATPSPKGAPTTPAAT 1224

Query: 258  APPP 261
             P P
Sbjct: 1225 PPSP 1228



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 25/64 (39%), Positives = 31/64 (48%), Gaps = 6/64 (9%)

Query: 198  APTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPGYR 257
            APT P+     A PP P  G    +P+G+  T  A P  P   G+ TP  +GAPT P   
Sbjct: 1194 APTTPA-----ATPPSPKGGLATPSPKGAPTTPAATPPSPKG-GLATPSPKGAPTTPAAT 1247

Query: 258  APPP 261
             P P
Sbjct: 1248 PPSP 1251



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 6/64 (9%)

Query: 198  APTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPGYR 257
            APT P+     A PP P  G     P+G+  T  A P  P   G+ TP  +GAPT P   
Sbjct: 1148 APTTPA-----ATPPSPKGGLATPPPKGAPTTPAATPPSPKG-GLATPSPKGAPTTPAAT 1201

Query: 258  APPP 261
             P P
Sbjct: 1202 PPSP 1205



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 6/64 (9%)

Query: 198  APTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPGYR 257
            APT P+     A PP P  G     P+G+  T  A P  P   G+ TP  +GAPT P   
Sbjct: 1125 APTTPA-----ATPPSPKGGLATPPPKGAPTTPAATPPSPKG-GLATPPPKGAPTTPAAT 1178

Query: 258  APPP 261
             P P
Sbjct: 1179 PPSP 1182



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 27/68 (39%), Positives = 34/68 (50%), Gaps = 7/68 (10%)

Query: 199  PTAPSRGRGGAIPP---PPPPGRGVLTP--RGSTVTRGALPVPPVARGVPTPRARGAPTV 253
            P  PS  +G  +PP   PP P  G+ TP  +G+  T  A P  P   G+ TP  +GAPT 
Sbjct: 1094 PATPSP-KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG-GLATPPPKGAPTT 1151

Query: 254  PGYRAPPP 261
            P    P P
Sbjct: 1152 PAATPPSP 1159



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 24/66 (36%), Positives = 29/66 (43%), Gaps = 8/66 (12%)

Query: 198  APTAPSRGRGGAIPPPPPPGRGVLTP--RGSTVTRGALPVPPVARGVPTPRARGAPTVPG 255
            APT P      A+ PP P G    TP  +G++    A P  P      TP  +GAPT P 
Sbjct: 1008 APTPP------AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPA 1061

Query: 256  YRAPPP 261
               P P
Sbjct: 1062 ATLPSP 1067



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 25/69 (36%), Positives = 30/69 (43%), Gaps = 6/69 (8%)

Query: 198  APTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPGYR 257
            APT P+     A PP P  G    +P+G+     A P  P   G  TP  +GAPT P   
Sbjct: 962  APTPPA-----ATPPSPKGGPATPSPKGAPTPPAATPPSPKG-GPATPSPKGAPTPPAVT 1015

Query: 258  APPPPAHEA 266
             P P    A
Sbjct: 1016 PPSPKGSPA 1024



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 12/71 (16%)

Query: 198  APTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALP-------VPPVARGVPTPRARGA 250
            APT P+     A PP P  G    +P+G+  T  A P         P  +G PTP A   
Sbjct: 1217 APTTPA-----ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP 1271

Query: 251  PTVPGYRAPPP 261
            P++ G  A PP
Sbjct: 1272 PSLKGGLATPP 1282



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 29/77 (37%), Positives = 35/77 (45%), Gaps = 14/77 (18%)

Query: 198  APTAPSRGRGGAIPP----PPPPGRGVLTPRGSTVT---RGALPVPPVAR------GVPT 244
            A T PS   G A P     P PP     +P+G   T   +GA P+PP A       G+ T
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGA-PMPPAATPPSPKGGLAT 1119

Query: 245  PRARGAPTVPGYRAPPP 261
            P  +GAPT P    P P
Sbjct: 1120 PPHKGAPTTPAATPPSP 1136



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 24/65 (36%), Positives = 30/65 (46%), Gaps = 7/65 (10%)

Query: 198  APTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPGYR 257
            APT P+     A PP P  G     P+G+     A P P +  G+ TP  +GAP  P   
Sbjct: 1240 APTTPA-----ATPPSPKGGPATPPPKGAPTPPAATP-PSLKGGLATPPHKGAPN-PAVV 1292

Query: 258  APPPP 262
             PP P
Sbjct: 1293 TPPSP 1297



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 22/69 (31%), Positives = 27/69 (39%), Gaps = 5/69 (7%)

Query: 198  APTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPGYR 257
            APT P+     A PP P  G    +P+G+       P  P      TP  +GA T P   
Sbjct: 985  APTPPA-----ATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT 1039

Query: 258  APPPPAHEA 266
             P P    A
Sbjct: 1040 PPSPKGSPA 1048



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 14/73 (19%)

Query: 198  APTAPSRGRGGAIPPPPPPGRGVLTPRGSTVT--------RGALPVPPVARGVPTPRARG 249
            APT P+     A PP P  G    +P+G+ +         +G L  PP  +G PT  A  
Sbjct: 1079 APTPPA-----ATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP-HKGAPTTPAAT 1132

Query: 250  APTVPGYRAPPPP 262
             P+  G  A PPP
Sbjct: 1133 PPSPKGGLATPPP 1145



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 29/78 (37%), Positives = 33/78 (42%), Gaps = 16/78 (20%)

Query: 198  APTAPSRGRGGAIPP-----------PPPPGRGVLT--PRGSTVTRGALPVPPVARGVP- 243
            A T PS   G A PP           PP P  G  T  P+G+     A   PP  +G P 
Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA--TPPSPKGSPG 1325

Query: 244  TPRARGAPTVPGYRAPPP 261
            TP  +GAPT P    P P
Sbjct: 1326 TPPPKGAPTPPAVTPPSP 1343



 Score = 35.8 bits (81), Expect = 0.059
 Identities = 27/76 (35%), Positives = 31/76 (40%), Gaps = 12/76 (15%)

Query: 198  APTAPSRGRGGAIPPPP----PPGR-------GVLTPRGSTVTRGALPVPPVARGVP-TP 245
            A T PS   G A PPP     PP         G+ TP        A+  PP  +G P T 
Sbjct: 1245 AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS 1304

Query: 246  RARGAPTVPGYRAPPP 261
              +GAPT P    P P
Sbjct: 1305 PPKGAPTPPAATPPSP 1320



 Score = 35.0 bits (79), Expect = 0.100
 Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 18/77 (23%)

Query: 198  APTAPSRGRGGAIPPPP----PPGRGVLTPRGSTVTRGALPVPPVARGVPTPRA------ 247
            A T PS   G A P P     PP     +P+G        P  P  +G PTP A      
Sbjct: 944  AATPPSPKGGPATPSPKWAPTPPAATPPSPKGG-------PATPSPKGAPTPPAATPPSP 996

Query: 248  RGAPTVPGYR-APPPPA 263
            +G P  P  + AP PPA
Sbjct: 997  KGGPATPSPKGAPTPPA 1013



 Score = 35.0 bits (79), Expect = 0.100
 Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 20/86 (23%)

Query: 198  APTAPSRGRGGAIPP----PPPPGRGVLTP--RGSTVTRGAL-------PVPPVARGVPT 244
            +P A    +G + PP    P P G    TP  +G+  T  A        P  P  +G PT
Sbjct: 1022 SPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPT 1081

Query: 245  PRA------RGAPTVPGYR-APPPPA 263
            P A      +G P  P  + AP PPA
Sbjct: 1082 PPAATPPSPKGGPATPSPKGAPMPPA 1107



 Score = 33.1 bits (74), Expect = 0.38
 Identities = 23/66 (34%), Positives = 29/66 (43%), Gaps = 7/66 (10%)

Query: 198  APTAPSRGRGGAIPPPPPPGRGVLTPRGST-VTRGALPVPPVARGVP-TPRARGAPTVPG 255
            AP  P    G A P      +G LTP   T V+    P     +G P TP ++G PT+P 
Sbjct: 1415 APATPVTREGAATP-----SKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPA 1469

Query: 256  YRAPPP 261
               P P
Sbjct: 1470 VTPPSP 1475



 Score = 32.7 bits (73), Expect = 0.50
 Identities = 20/67 (29%), Positives = 28/67 (41%), Gaps = 3/67 (4%)

Query: 199  PTAPSRGRGGAIPPPPPPGRG--VLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPGY 256
            P A    +GG    PP P RG  + +P+G   +   +P+ P  +   TP  R     P  
Sbjct: 1372 PAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP-KKAPATPVTREGAATPSK 1430

Query: 257  RAPPPPA 263
                PPA
Sbjct: 1431 GDLTPPA 1437



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 15/66 (22%)

Query: 197  IAPTAPSRGRGGAIPP--PPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRA------R 248
            + P +P  G   + P   P PP     +P+GS       P  P  +G PTP A      +
Sbjct: 1292 VTPPSPKGGPATSPPKGAPTPPAATPPSPKGS-------PGTPPPKGAPTPPAVTPPSPK 1344

Query: 249  GAPTVP 254
            G PT+P
Sbjct: 1345 GTPTLP 1350



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 13/81 (16%)

Query: 195 IRIAPTAPSRGRGGAIP---PPPPPGRGVLTPRGSTVT--RGALPVPPVARGVPTPRA-- 247
           + +  ++P + R    P   P  P  +G  TP  +T    +G  P  P  +  PTP A  
Sbjct: 911 LSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGG-PATPSPKWAPTPPAAT 969

Query: 248 ----RGAPTVPGYR-APPPPA 263
               +G P  P  + AP PPA
Sbjct: 970 PPSPKGGPATPSPKGAPTPPA 990



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 26/84 (30%), Positives = 30/84 (35%), Gaps = 13/84 (15%)

Query: 191  RGRGIRIAPTAPS-RGRGGAIPPP-----------PPPGRGVLTPRGSTVTRGALPVPPV 238
            +G     A T PS +G   A P P           P P  G  TP            PP 
Sbjct: 1030 KGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS 1089

Query: 239  ARGVP-TPRARGAPTVPGYRAPPP 261
             +G P TP  +GAP  P    P P
Sbjct: 1090 PKGGPATPSPKGAPMPPAATPPSP 1113



 Score = 28.9 bits (63), Expect = 7.2
 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 9/66 (13%)

Query: 198  APTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPGYR 257
            APT P      A+ PP P G   L P  +  ++G  P  P ++  PTP A   P+  G  
Sbjct: 1332 APTPP------AVTPPSPKGTPTL-PATTPSSKGG-PTTPSSKEGPTPPA-ATPSHKGGP 1382

Query: 258  APPPPA 263
            A  PP+
Sbjct: 1383 AMTPPS 1388


>gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]
          Length = 1096

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 45/142 (31%), Positives = 59/142 (41%), Gaps = 17/142 (11%)

Query: 109 DKAKEEELRKSGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIR 168
           +KAK EE     E K A  S +     E F    EA + +    E+IK+        EI+
Sbjct: 486 NKAKVEE----SEQKAAEFSKKFD---EEFTARQEAQAELQKRDEKIKEL-----EAEIQ 533

Query: 169 Q--EQLRELSYLNGSEDSGRGRGIRGRGIRIAPTAPSRGRGGAIPPPPPPGRGVL---TP 223
           Q   Q + LS  +G         + G G    P AP    G  +PPPPPP  G++    P
Sbjct: 534 QLRTQAQVLSSSSGIPGPPAAPPLPGVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPP 593

Query: 224 RGSTVTRGALPVPPVARGVPTP 245
               +  G  P PP   GVP P
Sbjct: 594 PPPPLLFGGPPPPPPLGGVPPP 615



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 22/64 (34%), Positives = 25/64 (39%), Gaps = 6/64 (9%)

Query: 203 SRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPG----YRA 258
           S G  G    PP PG G   P  +    G  P+PP     P P   G P  P     +  
Sbjct: 545 SSGIPGPPAAPPLPGVGPPPPPPAPPLPGGAPLPPPP--PPLPGMMGIPPPPPPPLLFGG 602

Query: 259 PPPP 262
           PPPP
Sbjct: 603 PPPP 606


>gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]
          Length = 1101

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 45/142 (31%), Positives = 59/142 (41%), Gaps = 17/142 (11%)

Query: 109 DKAKEEELRKSGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIR 168
           +KAK EE     E K A  S +     E F    EA + +    E+IK+        EI+
Sbjct: 486 NKAKVEE----SEQKAAEFSKKFD---EEFTARQEAQAELQKRDEKIKEL-----EAEIQ 533

Query: 169 Q--EQLRELSYLNGSEDSGRGRGIRGRGIRIAPTAPSRGRGGAIPPPPPPGRGVL---TP 223
           Q   Q + LS  +G         + G G    P AP    G  +PPPPPP  G++    P
Sbjct: 534 QLRTQAQVLSSSSGIPGPPAAPPLPGVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPP 593

Query: 224 RGSTVTRGALPVPPVARGVPTP 245
               +  G  P PP   GVP P
Sbjct: 594 PPPPLLFGGPPPPPPLGGVPPP 615



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 22/64 (34%), Positives = 25/64 (39%), Gaps = 6/64 (9%)

Query: 203 SRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPG----YRA 258
           S G  G    PP PG G   P  +    G  P+PP     P P   G P  P     +  
Sbjct: 545 SSGIPGPPAAPPLPGVGPPPPPPAPPLPGGAPLPPPP--PPLPGMMGIPPPPPPPLLFGG 602

Query: 259 PPPP 262
           PPPP
Sbjct: 603 PPPP 606


>gi|38150007 small nuclear ribonucleoprotein polypeptide B/B'
           isoform B' [Homo sapiens]
          Length = 240

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 31/75 (41%), Positives = 33/75 (44%), Gaps = 15/75 (20%)

Query: 198 APTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALP-------VPP---VARGVPTPRA 247
           APT    GRGG   PPPP GRG   P       G  P       +PP      G+P P  
Sbjct: 164 APTQYPPGRGG---PPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGM 220

Query: 248 RGAPTVPGYRAPPPP 262
           R  P  PG R PPPP
Sbjct: 221 R--PPPPGMRGPPPP 233



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 31/92 (33%), Positives = 39/92 (42%), Gaps = 18/92 (19%)

Query: 185 GRGRGIRGRGIRIA---PTAPSRGRGGAIPPPPPPGRGVLTPRG------------STVT 229
           G GR   GRGI      P AP+ G  G +     P + V+TP+G            +++ 
Sbjct: 105 GIGRAA-GRGIPAGVPMPQAPA-GLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIA 162

Query: 230 RGALPVPPVARGVPTPRARGAPTVPGYRAPPP 261
                 PP   G P P  RGAP  PG   PPP
Sbjct: 163 GAPTQYPPGRGGPPPPMGRGAPP-PGMMGPPP 193


>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
          Length = 502

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 26/59 (44%), Positives = 29/59 (49%), Gaps = 7/59 (11%)

Query: 210 IPPPPPPGRGV-LTPR-----GSTVTRGALPVPPVARGVPTPRARGAPTVPGYRAPPPP 262
           +PPPPPP RG    PR     G+    G LP  P+    P P  RG P  PG   PPPP
Sbjct: 313 LPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPP-PGRGGPPPP 370



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 30/76 (39%), Positives = 31/76 (40%), Gaps = 17/76 (22%)

Query: 199 PTAPSRGRGGAIPPPPPPG-----RGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTV 253
           P  PSRG G  +P PP  G      G L P    V  G  P PP  RG P P   G P  
Sbjct: 316 PPPPSRG-GNQLPRPPIVGGNKGRSGPLPP----VPLGIAPPPPTPRGPPPPGRGGPPPP 370

Query: 254 P-------GYRAPPPP 262
           P       G   PPPP
Sbjct: 371 PPPATGRSGPLPPPPP 386



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 27/78 (34%), Positives = 31/78 (39%), Gaps = 16/78 (20%)

Query: 186 RGRGIRGRGIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTP 245
           RG    GRG    P  P+ GR G +PPPPP               G  P+PP     P P
Sbjct: 357 RGPPPPGRGGPPPPPPPATGRSGPLPPPPPGA-------------GGPPMPPPPPPPPPP 403

Query: 246 RARGAPTVPGYRAPPPPA 263
            + G    P    P PPA
Sbjct: 404 PSSGNGPAP---PPLPPA 418


>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
          Length = 756

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 31/70 (44%), Positives = 31/70 (44%), Gaps = 7/70 (10%)

Query: 198 APTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPV----ARGVPTPRARGAPTV 253
           AP  P  G  GA PP PP G     P   T   GA PVPP     A  VP     GAP V
Sbjct: 615 APPVPPTGDSGA-PPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPV 673

Query: 254 P--GYRAPPP 261
           P  G   PPP
Sbjct: 674 PPTGDAGPPP 683



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 29/70 (41%), Positives = 29/70 (41%), Gaps = 7/70 (10%)

Query: 198 APTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTP----RARGAPTV 253
           AP  P  G  GA PP PP G     P   T   GA PVPP     P P       GAP V
Sbjct: 637 APPVPPTGDSGA-PPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPV 695

Query: 254 P--GYRAPPP 261
           P  G    PP
Sbjct: 696 PPTGDSGAPP 705



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 31/72 (43%), Positives = 32/72 (44%), Gaps = 9/72 (12%)

Query: 198 APTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPV----ARGVPTPRARGAPTV 253
           AP  P+ G  GA PP PP G     P   T   GA PVPP     A  VP     GAP V
Sbjct: 583 APVPPT-GDSGA-PPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPV 640

Query: 254 P---GYRAPPPP 262
           P      APP P
Sbjct: 641 PPTGDSGAPPVP 652



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 29/79 (36%), Positives = 31/79 (39%), Gaps = 9/79 (11%)

Query: 198 APTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARG----VPTPRARGAPTV 253
           AP  P  G  G  PP PP G     P   T   GA PV P        VP     GAP V
Sbjct: 670 APPVPPTGDAGP-PPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPV 728

Query: 254 P----GYRAPPPPAHEAYE 268
           P       AP PP  ++ E
Sbjct: 729 PPTGDSEAAPVPPTDDSKE 747



 Score = 32.3 bits (72), Expect = 0.65
 Identities = 24/58 (41%), Positives = 24/58 (41%), Gaps = 7/58 (12%)

Query: 212 PPPPPGRGVLTPRGSTVTRGALPVPPV----ARGVPTPRARGAPTVP---GYRAPPPP 262
           P PP G     P   T   GA PVPP     A  VP     GAP VP      APP P
Sbjct: 573 PVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVP 630



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 23/58 (39%), Positives = 23/58 (39%), Gaps = 7/58 (12%)

Query: 212 PPPPPGRGVLTPRGSTVTRGALPVPPV----ARGVPTPRARGAPTVP---GYRAPPPP 262
           P PP G    TP   T      PVPP     A  VP     GAP VP      APP P
Sbjct: 562 PVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVP 619


>gi|170016069 zinc finger, CCHC domain containing 2 [Homo sapiens]
          Length = 1178

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 32/78 (41%), Positives = 36/78 (46%), Gaps = 14/78 (17%)

Query: 201 APSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPT---VPGYR 257
           APSR R    PPPPPP      P G   +RG LP PP  RG+  P A GA     +PG  
Sbjct: 33  APSRRRRDCRPPPPPP-----PPAGP--SRGPLPPPPPPRGLGPPVAGGAAAGAGMPGGG 85

Query: 258 APPPPA----HEAYEEYG 271
             P  A       YE +G
Sbjct: 86  GGPSAALREQERVYEWFG 103



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 7/69 (10%)

Query: 202 PSRGRGGAIPPP--PPPGR----GVLTPRGSTVTRGALPVP-PVARGVPTPRARGAPTVP 254
           P+ G   A PP   P PG     GVL  + S+V   A   P P + G+   +A   P VP
Sbjct: 903 PAAGLSAAQPPASYPLPGSPLAAGVLPSQNSSVLSTAATSPQPASAGISQAQATVPPAVP 962

Query: 255 GYRAPPPPA 263
            +   P P+
Sbjct: 963 THTPGPAPS 971



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 22/54 (40%), Positives = 25/54 (46%), Gaps = 14/54 (25%)

Query: 199 PTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPT 252
           P  PSRG    +PPPPPP RG+    G  V  GA      A G   P   G P+
Sbjct: 50  PAGPSRG---PLPPPPPP-RGL----GPPVAGGA------AAGAGMPGGGGGPS 89


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 29/73 (39%), Positives = 35/73 (47%), Gaps = 9/73 (12%)

Query: 194 GIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRG-ALPVPPVARG---VPTPRARG 249
           G  I+P  P  G    IPPPPP   GV  P  S++  G A+P PP   G   +P P    
Sbjct: 627 GTAISPPPPLSG-DATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP---- 681

Query: 250 APTVPGYRAPPPP 262
            P +PG    PPP
Sbjct: 682 PPPLPGSAGIPPP 694



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 27/71 (38%), Positives = 30/71 (42%), Gaps = 9/71 (12%)

Query: 196 RIAPTAPSRGRGGAIPPPPP--PGRGVLTPRGSTVTRG-ALPVPPVARGVPTPRARG-AP 251
           RI P  P       IPPPPP  PG   + P    +  G  +P PP     P P   G  P
Sbjct: 677 RIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPP-----PFPGGPGIPP 731

Query: 252 TVPGYRAPPPP 262
             PG   PPPP
Sbjct: 732 PPPGMGMPPPP 742



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 17/67 (25%)

Query: 199 PTAPSRGRGGAIPPPPP-PGRGVLTPRGSTVTRGALPVPPV--ARGVPTPRARGAPTVPG 255
           P+  S   G AIPPPPP PG   + P          P PP+  + G+P P     P +PG
Sbjct: 655 PSPSSLPGGTAIPPPPPLPGSARIPP----------PPPPLPGSAGIPPP----PPPLPG 700

Query: 256 YRAPPPP 262
               PPP
Sbjct: 701 EAGMPPP 707



 Score = 35.4 bits (80), Expect = 0.077
 Identities = 47/180 (26%), Positives = 68/180 (37%), Gaps = 27/180 (15%)

Query: 107 MRDKAKEEELRKSGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIK--KFLVPDYN 164
           M DK K E+           L  EL    E+     +  S     L++++  K  +    
Sbjct: 459 MIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEK 518

Query: 165 DEI---RQEQLRELSYLNGS--------EDSGRGRG-IRGRGIRIAPTAPSRGRGGAIPP 212
            +I   +Q+   E+S L G         ED+ +    +    I + P+ PSR     +PP
Sbjct: 519 QQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSR---APVPP 575

Query: 213 PPP-PG-RGVLTPRGSTVTRGALPVPPVARGVPTPRARGA------PTVPGYRA--PPPP 262
            PP PG  G + P          P PP     P P   G       P++PG  A  PPPP
Sbjct: 576 APPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPP 635



 Score = 35.0 bits (79), Expect = 0.100
 Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 6/62 (9%)

Query: 199 PTAPSRGRGGAIPPPPP-PGRGVLTPRGSTVTRGALPVPPVARGVPTPRARG-----APT 252
           P  P  G  G  PPPPP PG   + P         +P PP   G+P P   G     AP 
Sbjct: 694 PPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPV 753

Query: 253 VP 254
           +P
Sbjct: 754 LP 755



 Score = 33.1 bits (74), Expect = 0.38
 Identities = 22/69 (31%), Positives = 25/69 (36%), Gaps = 4/69 (5%)

Query: 197 IAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPGY 256
           I P  P+ G     PPPPPP        G         +P      P P   G  T+P  
Sbjct: 586 IIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIP-- 643

Query: 257 RAPPPPAHE 265
             PPPP  E
Sbjct: 644 --PPPPLPE 650


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 29/73 (39%), Positives = 35/73 (47%), Gaps = 9/73 (12%)

Query: 194 GIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRG-ALPVPPVARG---VPTPRARG 249
           G  I+P  P  G    IPPPPP   GV  P  S++  G A+P PP   G   +P P    
Sbjct: 636 GTAISPPPPLSG-DATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP---- 690

Query: 250 APTVPGYRAPPPP 262
            P +PG    PPP
Sbjct: 691 PPPLPGSAGIPPP 703



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 27/71 (38%), Positives = 30/71 (42%), Gaps = 9/71 (12%)

Query: 196 RIAPTAPSRGRGGAIPPPPP--PGRGVLTPRGSTVTRG-ALPVPPVARGVPTPRARG-AP 251
           RI P  P       IPPPPP  PG   + P    +  G  +P PP     P P   G  P
Sbjct: 686 RIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPP-----PFPGGPGIPP 740

Query: 252 TVPGYRAPPPP 262
             PG   PPPP
Sbjct: 741 PPPGMGMPPPP 751



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 17/67 (25%)

Query: 199 PTAPSRGRGGAIPPPPP-PGRGVLTPRGSTVTRGALPVPPV--ARGVPTPRARGAPTVPG 255
           P+  S   G AIPPPPP PG   + P          P PP+  + G+P P     P +PG
Sbjct: 664 PSPSSLPGGTAIPPPPPLPGSARIPP----------PPPPLPGSAGIPPP----PPPLPG 709

Query: 256 YRAPPPP 262
               PPP
Sbjct: 710 EAGMPPP 716



 Score = 35.4 bits (80), Expect = 0.077
 Identities = 47/180 (26%), Positives = 68/180 (37%), Gaps = 27/180 (15%)

Query: 107 MRDKAKEEELRKSGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIK--KFLVPDYN 164
           M DK K E+           L  EL    E+     +  S     L++++  K  +    
Sbjct: 468 MIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMKKMESDFEQKLQDLQGEKDALHSEK 527

Query: 165 DEI---RQEQLRELSYLNGS--------EDSGRGRG-IRGRGIRIAPTAPSRGRGGAIPP 212
            +I   +Q+   E+S L G         ED+ +    +    I + P+ PSR     +PP
Sbjct: 528 QQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSR---APVPP 584

Query: 213 PPP-PG-RGVLTPRGSTVTRGALPVPPVARGVPTPRARGA------PTVPGYRA--PPPP 262
            PP PG  G + P          P PP     P P   G       P++PG  A  PPPP
Sbjct: 585 APPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPP 644



 Score = 35.0 bits (79), Expect = 0.100
 Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 6/62 (9%)

Query: 199 PTAPSRGRGGAIPPPPP-PGRGVLTPRGSTVTRGALPVPPVARGVPTPRARG-----APT 252
           P  P  G  G  PPPPP PG   + P         +P PP   G+P P   G     AP 
Sbjct: 703 PPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPV 762

Query: 253 VP 254
           +P
Sbjct: 763 LP 764



 Score = 33.1 bits (74), Expect = 0.38
 Identities = 22/69 (31%), Positives = 25/69 (36%), Gaps = 4/69 (5%)

Query: 197 IAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPGY 256
           I P  P+ G     PPPPPP        G         +P      P P   G  T+P  
Sbjct: 595 IIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIP-- 652

Query: 257 RAPPPPAHE 265
             PPPP  E
Sbjct: 653 --PPPPLPE 659


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 26/68 (38%), Positives = 28/68 (41%), Gaps = 4/68 (5%)

Query: 198 APTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARG---APTVP 254
           AP  P    G  +PPPPPP    L P  S       P PP+      P   G   AP  P
Sbjct: 668 APPMPPVSAGPPLPPPPPP-PPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPP 726

Query: 255 GYRAPPPP 262
           G   PPPP
Sbjct: 727 GLAPPPPP 734



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 38/136 (27%), Positives = 55/136 (40%), Gaps = 30/136 (22%)

Query: 136 EVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLRELSYLNGSEDSGRG----RGIR 191
           E F  P E+ S+ + + + + K        ++    L +LS  N  +D         G+ 
Sbjct: 587 ETFLKPCESESKTTRSNQLVPK--------KLNISSLSQLSPPNDHKDIHAALQPMEGMA 638

Query: 192 GRGIRIAPTAPSRGRGGAIPPPPP--PGRGVLTPRGSTVTRGALPVPPVARGVPTPRARG 249
               +  P  P+     +IPPPPP   G G L+P        A P+PPV+ G P P    
Sbjct: 639 SNQQKALPPPPA-----SIPPPPPLPSGLGSLSP--------APPMPPVSAGPPLPPPPP 685

Query: 250 AP---TVPGYRAPPPP 262
            P     P    PPPP
Sbjct: 686 PPPPLPPPSSAGPPPP 701


>gi|116292174 fidgetin-like 2 [Homo sapiens]
          Length = 653

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 4/86 (4%)

Query: 208 GAIPPPP-PPGRGVLTPRGSTVTRGALPVPPVARGVPT--PRARGAPTVPGYRAPPPPAH 264
           GA+PPPP PP    LTP     T    P PP A G PT  P A    ++    A   P  
Sbjct: 217 GALPPPPGPPPAPYLTPGLPAPTPLPAPAPPTAYGFPTAAPGAESGLSLKRKAADEGP-E 275

Query: 265 EAYEEYGYDDGYGGEYDDQTYETYDN 290
             Y +Y Y+       D  +Y   DN
Sbjct: 276 GRYRKYAYEPAKAPVADGASYPAADN 301



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 33/113 (29%), Positives = 43/113 (38%), Gaps = 24/113 (21%)

Query: 194 GIRIAPTAPSRGRGGAIPPPPPPGRGVLT-----PRGSTVTR---GALPVPP-------V 238
           G  + P  P+      + PPPPPG G        P G    +   GALP PP       +
Sbjct: 176 GAALPPPPPA----ALLQPPPPPGYGPSAPLYNYPAGGYAAQPGYGALPPPPGPPPAPYL 231

Query: 239 ARGVPTPRARGAPTVP---GYRAPPPPAHE--AYEEYGYDDGYGGEYDDQTYE 286
             G+P P    AP  P   G+    P A    + +    D+G  G Y    YE
Sbjct: 232 TPGLPAPTPLPAPAPPTAYGFPTAAPGAESGLSLKRKAADEGPEGRYRKYAYE 284


>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
           sapiens]
          Length = 572

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 17/120 (14%)

Query: 3   EEKYLPELMAEKDSLDPSFVHASRLLAEEIEKFQGSDGKKEDEEKKYLDVISNKNIKLSE 62
           E   +PE          S   A RLL + +++ +   G   D       + SN  I   +
Sbjct: 116 ESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHND-------IDSNSTI---Q 165

Query: 63  RVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRKSGEA 122
            +LIP  +      VG ++G  G ++K+LQE TG KM ++  G +   A ++ LR +G+A
Sbjct: 166 EILIPASK------VGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGA-DKPLRITGDA 218



 Score = 28.9 bits (63), Expect = 7.2
 Identities = 21/98 (21%), Positives = 45/98 (45%), Gaps = 7/98 (7%)

Query: 9   ELMAEKDSLDPSFVHASRLLAEEIEKFQGSDGKKEDEEKKYLDVISNKNIKLSERVLIPV 68
           ++ A+ DS+ P   +++ L+   +  +       +D     L  + ++   ++E   +P 
Sbjct: 28  QIAAKIDSI-PHLNNSTPLVDPSVYGYGVQKRPLDDGVGNQLGALVHQRTVITEEFKVPD 86

Query: 69  KQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGS 106
           K       VG ++G  G  + R+Q E+G K+ I  + S
Sbjct: 87  KM------VGFIIGRGGEQISRIQAESGCKIQIASESS 118


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 27/72 (37%), Positives = 29/72 (40%), Gaps = 4/72 (5%)

Query: 191 RGRGIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGA 250
           RGR  R     P+R R    P PPP  R   TP      R   P PP  R  P+PR    
Sbjct: 543 RGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPP----PRRRTPSPPPRRRSPSPRRYSP 598

Query: 251 PTVPGYRAPPPP 262
           P    Y   PPP
Sbjct: 599 PIQRRYSPSPPP 610



 Score = 29.3 bits (64), Expect = 5.5
 Identities = 20/67 (29%), Positives = 27/67 (40%), Gaps = 1/67 (1%)

Query: 196 RIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPG 255
           R A ++P R R    P   P  R   TP    + + A P P   R V + R+      P 
Sbjct: 702 RGASSSPQR-RQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPA 760

Query: 256 YRAPPPP 262
            + PP P
Sbjct: 761 AKKPPAP 767



 Score = 28.9 bits (63), Expect = 7.2
 Identities = 32/140 (22%), Positives = 47/140 (33%), Gaps = 10/140 (7%)

Query: 196 RIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPG 255
           R +P+ P + R  + PPPPP  R   +P      R +   PP  R  P  + R       
Sbjct: 603 RYSPSPPPKRRTAS-PPPPPKRRA--SPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSK 659

Query: 256 YRAPPPPAHEAYEEYGYDDGYGGEYDDQTYETYDNSYATQTQSVPEYYDYGHGVSEDAYD 315
           +R    P+    E             ++ +       A QT S P     G   S     
Sbjct: 660 HRKGSSPSRSTREA-------RSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQ 712

Query: 316 SYAPEEWATTRSSLKAPPQR 335
           S +P      R S    P++
Sbjct: 713 SPSPSTRPIRRVSRTPEPKK 732


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 33/96 (34%), Positives = 36/96 (37%), Gaps = 22/96 (22%)

Query: 184 SGRGRGIRGRGIRIAPTAPSRGRGGAIPPPPPPGR-----------GVLTPRGSTVTRGA 232
           SG   G  G G    P AP+ G  GA P PPP GR           G  +PR   V  G 
Sbjct: 64  SGSPAGAAGAG----PAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAG- 118

Query: 233 LPVPPVARGVPTPRARG-----APTVPGYRAPPPPA 263
            P PP A+  P P          P      A P PA
Sbjct: 119 -PAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPA 153



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 24/74 (32%), Positives = 27/74 (36%), Gaps = 13/74 (17%)

Query: 199 PTAPSRGRGGAIPPPPPPGRGVLT-----PRGSTVTRGALPVPPVARG--------VPTP 245
           P AP+     A PPPPPP    L      P G      A+P P  A+          P P
Sbjct: 258 PAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAP 317

Query: 246 RARGAPTVPGYRAP 259
            A G   V G   P
Sbjct: 318 AAGGPAGVSGQPGP 331



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 20/53 (37%), Positives = 23/53 (43%), Gaps = 6/53 (11%)

Query: 210 IPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPGYRAPPPP 262
           +P P  PG  + TP        A P  P A   P+P A  AP  P    PPPP
Sbjct: 228 LPKPAAPGTVIQTP---PFVGAAAPPAPAA---PSPPAAPAPAAPAAAPPPPP 274



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 24/69 (34%), Positives = 28/69 (40%), Gaps = 6/69 (8%)

Query: 197 IAPTAPSRGRGGAIPPPPPPGRGVLTPRGS--TVTRGALPVP-PVARGVPTPRARGAPTV 253
           I PT        A  PPP PG     P+G+   VT+     P     G+   RA   PTV
Sbjct: 375 IGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGI---RATLTPTV 431

Query: 254 PGYRAPPPP 262
              R P PP
Sbjct: 432 LAPRLPQPP 440


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 23/56 (41%), Positives = 31/56 (55%), Gaps = 6/56 (10%)

Query: 208 GAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVP-TPRARGAPTVPGYRAPPPP 262
           GA PPPPPP  G+ +P+ +  +      PP A  +P +P    AP +PG   PPPP
Sbjct: 539 GAAPPPPPPLPGLPSPQEAPPS-----APPQAPPLPGSPEPPPAPPLPGDLPPPPP 589



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 31/93 (33%), Positives = 38/93 (40%), Gaps = 13/93 (13%)

Query: 182 EDSGRGRGIRGRG----IRIAPTAPSRGRGGAIPPPPPPGRGV---LTPRGSTVTRGALP 234
           E+ G  R +RG G    I I P A +   GG  P P  P       L P        A P
Sbjct: 484 EEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPP 543

Query: 235 VPPVARGVPTPRAR------GAPTVPGYRAPPP 261
            PP   G+P+P+         AP +PG   PPP
Sbjct: 544 PPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPP 576



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 24/60 (40%), Positives = 26/60 (43%), Gaps = 7/60 (11%)

Query: 204 RGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTP-RARGAPTVPGYRAPPPP 262
           RG G A+     P   V TP G     G  P P V  G P+P  A  A   PG   PPPP
Sbjct: 493 RGPGDAVSIEILPV-AVATPSG-----GDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPP 546



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 23/67 (34%), Positives = 25/67 (37%), Gaps = 17/67 (25%)

Query: 199 PTAPSRGR---GGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPG 255
           P+AP +     G   PPP PP  G L P          P PP     P P     P  P 
Sbjct: 559 PSAPPQAPPLPGSPEPPPAPPLPGDLPP----------PPPP----PPPPPGTDGPVPPP 604

Query: 256 YRAPPPP 262
              PPPP
Sbjct: 605 PPPPPPP 611



 Score = 28.9 bits (63), Expect = 7.2
 Identities = 21/59 (35%), Positives = 22/59 (37%), Gaps = 12/59 (20%)

Query: 199 PTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPGYR 257
           P  P  G     PPPPPP  G         T G +P PP     P P   G P   G R
Sbjct: 576 PAPPLPGDLPPPPPPPPPPPG---------TDGPVPPPPPP---PPPPPGGPPDALGRR 622


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.134    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,092,062
Number of Sequences: 37866
Number of extensions: 1166289
Number of successful extensions: 10604
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 188
Number of HSP's successfully gapped in prelim test: 715
Number of HSP's that attempted gapping in prelim test: 6959
Number of HSP's gapped (non-prelim): 3090
length of query: 349
length of database: 18,247,518
effective HSP length: 103
effective length of query: 246
effective length of database: 14,347,320
effective search space: 3529440720
effective search space used: 3529440720
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.