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Search of human proteins with 187607445
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|187607445 hypothetical protein LOC79137 [Homo sapiens]
(543 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|187607445 hypothetical protein LOC79137 [Homo sapiens] 1082 0.0
gi|30023820 hypothetical protein LOC162427 [Homo sapiens] 232 7e-61
gi|77917617 hypothetical protein LOC54463 isoform 1 [Homo sapiens] 173 3e-43
gi|21361617 hypothetical protein LOC54463 isoform 2 [Homo sapiens] 145 7e-35
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 54 3e-07
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 49 2e-05
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 49 2e-05
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 49 2e-05
gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens] 48 3e-05
gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens] 48 3e-05
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 47 3e-05
gi|55741677 SET domain containing 1A [Homo sapiens] 46 8e-05
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 46 8e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 46 8e-05
gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens] 45 1e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 44 3e-04
gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 44 5e-04
gi|153792074 proline rich 12 [Homo sapiens] 44 5e-04
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 43 6e-04
gi|223633941 hypothetical protein LOC389730 [Homo sapiens] 42 0.001
gi|91206406 hypothetical protein LOC642265 [Homo sapiens] 42 0.001
gi|146231958 hypothetical protein LOC647060 [Homo sapiens] 42 0.001
gi|24308007 ADP-ribosylation factor-like 6 interacting protein [... 42 0.001
gi|169174618 PREDICTED: family with sequence similarity 75, memb... 42 0.001
gi|239743732 PREDICTED: family with sequence similarity 75, memb... 42 0.001
gi|153791826 hypothetical protein LOC26165 [Homo sapiens] 42 0.001
gi|133892686 hypothetical protein LOC727830 [Homo sapiens] 42 0.001
gi|165377334 hypothetical protein LOC727905 [Homo sapiens] 42 0.001
gi|33356148 formin-like 1 [Homo sapiens] 41 0.002
gi|83367077 mucin 16 [Homo sapiens] 41 0.003
>gi|187607445 hypothetical protein LOC79137 [Homo sapiens]
Length = 543
Score = 1082 bits (2797), Expect = 0.0
Identities = 543/543 (100%), Positives = 543/543 (100%)
Query: 1 MASGGGGGNTGAGGGPGMGLSLGLGLGLSLGMSEATSEAEEEAATAEAVGRLATTLWLRL 60
MASGGGGGNTGAGGGPGMGLSLGLGLGLSLGMSEATSEAEEEAATAEAVGRLATTLWLRL
Sbjct: 1 MASGGGGGNTGAGGGPGMGLSLGLGLGLSLGMSEATSEAEEEAATAEAVGRLATTLWLRL 60
Query: 61 RGWEAVLAAAQRLLVWEKPLHSLVTAAALNGLFWLLSSSSLRPFFLLSVSLLAYFLLDLW 120
RGWEAVLAAAQRLLVWEKPLHSLVTAAALNGLFWLLSSSSLRPFFLLSVSLLAYFLLDLW
Sbjct: 61 RGWEAVLAAAQRLLVWEKPLHSLVTAAALNGLFWLLSSSSLRPFFLLSVSLLAYFLLDLW 120
Query: 121 QPRFLPDVSASSPEEPHSDSEGAGSGARPHLLSVPELCRYLAESWLTFQIHLQELLQYKR 180
QPRFLPDVSASSPEEPHSDSEGAGSGARPHLLSVPELCRYLAESWLTFQIHLQELLQYKR
Sbjct: 121 QPRFLPDVSASSPEEPHSDSEGAGSGARPHLLSVPELCRYLAESWLTFQIHLQELLQYKR 180
Query: 181 QNPAQFCVRVCSGCAVLAVLGHYVPGIMISYIVLLSILLWPLVVYHELIQRMYTRLEPLL 240
QNPAQFCVRVCSGCAVLAVLGHYVPGIMISYIVLLSILLWPLVVYHELIQRMYTRLEPLL
Sbjct: 181 QNPAQFCVRVCSGCAVLAVLGHYVPGIMISYIVLLSILLWPLVVYHELIQRMYTRLEPLL 240
Query: 241 MQLDYSMKAEANALHHKHDKRKRQGKNAPPGGDEPLAETESESEAELAGFSPVVDVKKTA 300
MQLDYSMKAEANALHHKHDKRKRQGKNAPPGGDEPLAETESESEAELAGFSPVVDVKKTA
Sbjct: 241 MQLDYSMKAEANALHHKHDKRKRQGKNAPPGGDEPLAETESESEAELAGFSPVVDVKKTA 300
Query: 301 LALAITDSELSDEEASILESGGFSVSRATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEG 360
LALAITDSELSDEEASILESGGFSVSRATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEG
Sbjct: 301 LALAITDSELSDEEASILESGGFSVSRATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEG 360
Query: 361 EEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPD 420
EEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPD
Sbjct: 361 EEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPD 420
Query: 421 GVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPA 480
GVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPA
Sbjct: 421 GVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPA 480
Query: 481 PEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPPLGPDIHSLVQSDQEAQAV 540
PEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPPLGPDIHSLVQSDQEAQAV
Sbjct: 481 PEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPPLGPDIHSLVQSDQEAQAV 540
Query: 541 AEP 543
AEP
Sbjct: 541 AEP 543
>gi|30023820 hypothetical protein LOC162427 [Homo sapiens]
Length = 466
Score = 232 bits (591), Expect = 7e-61
Identities = 154/451 (34%), Positives = 231/451 (51%), Gaps = 49/451 (10%)
Query: 63 WEAVLAAAQRLLVWEKPLHSLVTAAALNGLFWLLSSSSLRPFFLLSVSLLAYFLLDLWQP 122
+E +L+ Q LVWE+P S + LN FW + +SLR FLL+ L+ +D W+
Sbjct: 49 YEPLLSRVQAALVWERPARSALWCLGLNAAFWFFALTSLRLVFLLAFGLMIIVCIDQWKN 108
Query: 123 RFLPDVSASSPEEPHSDSEGAGSGARPHLLSVPELCRYLAESWLTFQIHLQELLQYKRQN 182
+ P++ P+ ++S G P LLSVPELC ++AE W++ I ++ +L +K+QN
Sbjct: 109 KIWPEIKVPRPDALDNESWGF---VHPRLLSVPELCHHVAEVWVSGTIFIRNVLLFKKQN 165
Query: 183 PAQFCVRVCSGCAVLAVLGHYVPGIMISYIVLLSILLWPLVVYHELIQRMYTRLEPLLMQ 242
P +FC+ C LAVLG YVPG+++SY++L+++++WPL VYH L R Y RL+P L +
Sbjct: 166 PGKFCLLSCGILTFLAVLGRYVPGLLLSYLMLVTVMMWPLAVYHRLWDRAYVRLKPALQR 225
Query: 243 LDYSMKAEANALHHKHDKRKRQGKNAPPGGDEPLAETESESEAELAGFSPVVDVKKTALA 302
LD+S++ + + R+R E + S+SE ELA F P +D A
Sbjct: 226 LDFSVRGYMMSKQRERQLRRRALH------PERAMDNHSDSEEELAAFCPQLDDSTVARE 279
Query: 303 LAITDSELSDEEASILESGGFSVSRATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEGEE 362
LAITDSE SD E S ++G F++SR TP LT+ SEDLD S +PEE+ +RDL +
Sbjct: 280 LAITDSEHSDAEVSCTDNGTFNLSRGQTP-LTEGSEDLDGHS---DPEESFARDLPDFPS 335
Query: 363 GELAPP------EDLLGRPQALSRQALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAG 416
+ P + +G P + R +EE + A+++ A
Sbjct: 336 INMDPAGLDDEDDTSIGMPSLMYRSPPGAEEPQAPPASRDE-----------------AA 378
Query: 417 SPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCLVG-SDPAPSPSILPPVPQDSP 475
P + P G ++ L +L L L G S P PS + P + +
Sbjct: 379 LPELLLGALPVG-------SNLTSNLASLVSQGMIQLALSGASQPGPSGA---PAQRATR 428
Query: 476 QPLPAPEEEEALTTE--DFELLDQGELEQLN 504
L +P + E DFELLDQ EL QL+
Sbjct: 429 GFLRSPSSDLDTDAEGDDFELLDQSELSQLD 459
>gi|77917617 hypothetical protein LOC54463 isoform 1 [Homo sapiens]
Length = 497
Score = 173 bits (439), Expect = 3e-43
Identities = 143/498 (28%), Positives = 232/498 (46%), Gaps = 84/498 (16%)
Query: 23 GLGLGLSLGMSEATSEAEEEAATAEAVGRLATTLWLRLRGWEAVLAAAQRLLVWEKPLHS 82
G G L + EA A AA +G LWL R A LL W++PL S
Sbjct: 48 GAAEGAGLQVEEAAGRAA--AAVTWLLGE--PVLWLGCR--------ADELLSWKRPLRS 95
Query: 83 LVTAAALNGLFWLLSSSSLRPFFLLSVSLLAYFLLDLWQPRFLPDVSASSPEEPHSDSEG 142
L+ A N LFW L+ + R + L+SV +L ++ + + L + S+S
Sbjct: 96 LLGFVAANLLFWFLALTPWRVYHLISVMILGRVIMQIIKDMVLSRTRGAQLWRSLSESWE 155
Query: 143 AGSGARPHLLSVPELCRYLAESWLTFQIHLQELLQYKRQNPAQFCVRVCSGCAVLAVLGH 202
++P P L +AESW+ F I LQE+ +K+Q+P +FC+ VCS C +LG
Sbjct: 156 V-INSKPD--ERPRLSHCIAESWMNFSIFLQEMSLFKQQSPGKFCLLVCSVCTFFTILGS 212
Query: 203 YVPGIMISYIVLLSILLWPLVVYHELIQRMYTRLEPLLMQLDYSMKAEANALHHKHDKRK 262
Y+PG+++SY++LL L PL +++ Q++Y++++ +L++LD+ + N ++K
Sbjct: 213 YIPGVILSYLLLLCAFLCPLFKCNDIGQKIYSKIKSVLLKLDFGIGEYIN-------QKK 265
Query: 263 RQGKNAPPGGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGG 322
R+ A + + +SE + + P + + A L+++D+++S E S ++G
Sbjct: 266 RERSEA-----DKEKSHKDDSELDFSALCPKISLTVAAKELSVSDTDVS--EVSWTDNGT 318
Query: 323 FSVSRATTPQLTDVSEDLDQQSLPSEPEETLSRDL----------GEGEEGELAPPEDLL 372
F++S TPQ TD S+DLD+ S EE SRDL G +E EL+ L
Sbjct: 319 FNLSEGYTPQ-TDTSDDLDRPS-----EEVFSRDLSDFPSLENGMGTNDEDELS-----L 367
Query: 373 GRPQALSRQALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVET 432
G P L R+ + ++ L+ PL+ T +
Sbjct: 368 GLPTELKRKKEQLDSGHRPSKETQSAAGLTLPLNSDQTFH----------------LMSN 411
Query: 433 LSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEE-EALTTED 491
L+ + ++ +T A L V Q Q P PEE+ + +D
Sbjct: 412 LAGDVITAAVT-----------------AAIKDQLEGVQQALSQAAPIPEEDTDTEEGDD 454
Query: 492 FELLDQGELEQLNAELGL 509
FELLDQ EL+Q+ +ELGL
Sbjct: 455 FELLDQSELDQIESELGL 472
>gi|21361617 hypothetical protein LOC54463 isoform 2 [Homo sapiens]
Length = 356
Score = 145 bits (367), Expect = 7e-35
Identities = 107/366 (29%), Positives = 178/366 (48%), Gaps = 69/366 (18%)
Query: 155 PELCRYLAESWLTFQIHLQELLQYKRQNPAQFCVRVCSGCAVLAVLGHYVPGIMISYIVL 214
P L +AESW+ F I LQE+ +K+Q+P +FC+ VCS C +LG Y+PG+++SY++L
Sbjct: 24 PRLSHCIAESWMNFSIFLQEMSLFKQQSPGKFCLLVCSVCTFFTILGSYIPGVILSYLLL 83
Query: 215 LSILLWPLVVYHELIQRMYTRLEPLLMQLDYSMKAEANALHHKHDKRKRQGKNAPPGGDE 274
L L PL +++ Q++Y++++ +L++LD+ + N ++KR+ A +
Sbjct: 84 LCAFLCPLFKCNDIGQKIYSKIKSVLLKLDFGIGEYIN-------QKKRERSEA-----D 131
Query: 275 PLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGGFSVSRATTPQLT 334
+ +SE + + P + + A L+++D+++S E S ++G F++S TPQ T
Sbjct: 132 KEKSHKDDSELDFSALCPKISLTVAAKELSVSDTDVS--EVSWTDNGTFNLSEGYTPQ-T 188
Query: 335 DVSEDLDQQSLPSEPEETLSRDL----------GEGEEGELAPPEDLLGRPQALSRQALD 384
D S+DLD+ S EE SRDL G +E EL+ LG P L R+
Sbjct: 189 DTSDDLDRPS-----EEVFSRDLSDFPSLENGMGTNDEDELS-----LGLPTELKRKKEQ 238
Query: 385 SEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTA 444
+ ++ L+ PL+ T + L+ + ++ +T
Sbjct: 239 LDSGHRPSKETQSAAGLTLPLNSDQTFH----------------LMSNLAGDVITAAVT- 281
Query: 445 LPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEE-EALTTEDFELLDQGELEQL 503
A L V Q Q P PEE+ + +DFELLDQ EL+Q+
Sbjct: 282 ----------------AAIKDQLEGVQQALSQAAPIPEEDTDTEEGDDFELLDQSELDQI 325
Query: 504 NAELGL 509
+ELGL
Sbjct: 326 ESELGL 331
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 54.3 bits (129), Expect = 3e-07
Identities = 74/269 (27%), Positives = 102/269 (37%), Gaps = 29/269 (10%)
Query: 268 APPGGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGGFSVSR 327
+PP + PL+ S SP+ +++ + A+ EAS L S F S
Sbjct: 495 SPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPL-SPPFEESP 553
Query: 328 ATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEGEEGELAPP--EDLLGRPQALSRQALDS 385
+ P + LP+ P SR EE ++PP E + P SR
Sbjct: 554 LSPPP----------EELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPF 603
Query: 386 EE-------EEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETV 438
EE EE ++ RLS P + PP+ SP V LSP V
Sbjct: 604 EESPLSPPPEESPLSPPPEASRLSPP-----PEDSPMSPPPEESPMSPPPEVSRLSPLPV 658
Query: 439 SGGLTALP--GTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLD 496
L+ P LSPP + P P S L P P+DSP P PE+ A + L+
Sbjct: 659 VSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTS-PPPEDSPASPPPEDSLMS 717
Query: 497 QGELEQLNAELGLEPETPPKPPDAPPLGP 525
E L EP+ P+ + P L P
Sbjct: 718 LPLEESPLLPLPEEPQLCPR-SEGPHLSP 745
Score = 45.8 bits (107), Expect = 1e-04
Identities = 61/254 (24%), Positives = 86/254 (33%), Gaps = 31/254 (12%)
Query: 314 EASILESGGFSVSRATTPQLTDVSEDLDQQSLPSEPEETL------SRDLGEGEEGELAP 367
EAS L + + P+ +S L++ L PEE+ S EE L+P
Sbjct: 463 EASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSP 522
Query: 368 PEDLLGRPQALSRQALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPG 427
PE+ P L E ++ LS P + T PP+ + SP
Sbjct: 523 PEE--SPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPT-----SPPPEASRLSPP 575
Query: 428 GPVETLSPETVSGGLTALP-----------GTLSPPLCLVGSDPAPSPSILPPVPQDSPQ 476
+SP ++ P LSPP P P S L P P+DSP
Sbjct: 576 PEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPM 635
Query: 477 PLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPP-------KPPDAPPLGPDIHS 529
P E + E L + +L+ P +PP PP+A L P
Sbjct: 636 SPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPED 695
Query: 530 LVQSDQEAQAVAEP 543
S + A P
Sbjct: 696 SPTSPPPEDSPASP 709
Score = 38.9 bits (89), Expect = 0.012
Identities = 51/190 (26%), Positives = 71/190 (37%), Gaps = 19/190 (10%)
Query: 346 PSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKETLLRLSSPL 405
P+ P SR EE +P + L + L L EE ++ SSP
Sbjct: 457 PTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPE----SSPF 512
Query: 406 HFVNTHFNGAGSPPDGVKCSPGGPVET-LSPETVSGGLTAL--PGTLSPPLCLVGSDPAP 462
+ SPP+ SP +ET LSP + L+ LSPP + + P P
Sbjct: 513 SPLE---ESPLSPPEESPPSPA--LETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPP 567
Query: 463 SPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPP------- 515
S L P P++SP P E + E L E L+ P +PP
Sbjct: 568 EASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLS 627
Query: 516 KPPDAPPLGP 525
PP+ P+ P
Sbjct: 628 PPPEDSPMSP 637
Score = 38.1 bits (87), Expect = 0.021
Identities = 37/123 (30%), Positives = 44/123 (35%), Gaps = 15/123 (12%)
Query: 418 PPDGVKCSPGGPVETLSPETVSGGLTALPGT--LSPPLCLVGSDPAPSPSILPPVPQDSP 475
PP+ SP LSP + LP LS PL P P S L P P+ SP
Sbjct: 452 PPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSP 511
Query: 476 ------QPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPP-------KPPDAPP 522
PL PEE + L E L+ P +PP PP+A
Sbjct: 512 FSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASR 571
Query: 523 LGP 525
L P
Sbjct: 572 LSP 574
Score = 37.4 bits (85), Expect = 0.035
Identities = 33/105 (31%), Positives = 43/105 (40%), Gaps = 13/105 (12%)
Query: 418 PPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPL--CLVGSDPAPSPSILPPVPQDSP 475
PP + SPG PV SP + LP SP L LV + PS P +P P
Sbjct: 997 PPMILPPSPGSPVGPASPILME----PLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVP 1052
Query: 476 QPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDA 520
PL + ++ D+ EL ++ E EPE P P A
Sbjct: 1053 SPLSPIGKVVGVS-------DEAELHEMETEKVSEPECPALEPSA 1090
Score = 34.3 bits (77), Expect = 0.30
Identities = 74/308 (24%), Positives = 106/308 (34%), Gaps = 49/308 (15%)
Query: 230 QRMYTRLEPLLMQLDYSMKAEANALHH-KHDKRKRQGKNAPPGGDEPLAETESESEAELA 288
QR RL LL++ + + N L K G PPG AE S + +L+
Sbjct: 2680 QRQRQRLRELLIR----QQIQRNTLRQEKETAAAAAGAVGPPGSWG--AEPSSPAFEQLS 2733
Query: 289 -GFSPVVDVKKTALALAITDSELSDEEASILESGGFSVSRATT---PQLTDVSEDLDQQS 344
G +P + + + + S+LS IL G F + P T S D++ +
Sbjct: 2734 RGQTPFAGTQDKSSLVGLPPSKLS---GPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQ 2790
Query: 345 LPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKETLL---RL 401
L + R G + L + QA + ++ + L L
Sbjct: 2791 LVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQAL 2850
Query: 402 SSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLS-PETVSGGLTALPGTLSPPLCLVGSDP 460
SPL ++T G G P G P GP + + V GL G
Sbjct: 2851 GSPLAGISTRLPGPGEPVPG----PAGPAQFIELRHNVQKGL--------------GPGG 2892
Query: 461 APSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDA 520
P P PP P+ P E+ L E L A GL P+ P PP A
Sbjct: 2893 TPFPGQGPP---QRPRFYPVSEDPHRLAPEGLRGL---------AVSGLPPQKPSAPP-A 2939
Query: 521 PPLGPDIH 528
P L +H
Sbjct: 2940 PELNNSLH 2947
Score = 33.1 bits (74), Expect = 0.67
Identities = 26/84 (30%), Positives = 33/84 (39%), Gaps = 2/84 (2%)
Query: 460 PAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPD 519
P P S L P P++SP P E L+ EL E L+ LE PP+
Sbjct: 442 PPPEESPLSPPPEESPTS--PPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPE 499
Query: 520 APPLGPDIHSLVQSDQEAQAVAEP 543
PL P S S E ++ P
Sbjct: 500 ESPLSPPPESSPFSPLEESPLSPP 523
Score = 33.1 bits (74), Expect = 0.67
Identities = 39/134 (29%), Positives = 50/134 (37%), Gaps = 27/134 (20%)
Query: 418 PPDGVKCSPGGP---VETLSPETVSGGL----TALPG-TLSPPLCLVGSDPAPSPSILPP 469
P G PGG +E SP+T L LPG TL L IL
Sbjct: 4830 PKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQL-----------DILSL 4878
Query: 470 VPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPPLGPDIHS 529
+ Q+SP P P + + ++ QL+A EP PP P P P
Sbjct: 4879 LKQESPAPEPPTQHSYTYNVSNLDV------RQLSAPPPEEPSPPPSPLAPSPASPPTEP 4932
Query: 530 LVQSDQEAQAVAEP 543
LV+ E +AEP
Sbjct: 4933 LVELPTE--PLAEP 4944
Score = 32.3 bits (72), Expect = 1.1
Identities = 32/104 (30%), Positives = 45/104 (43%), Gaps = 13/104 (12%)
Query: 449 LSPPLCLVGSDPAPSPSILPPVPQDSP-QPLP------APEEEEALT--TEDFELLDQGE 499
LSPP + P P S L P P++ P PLP P EE L+ E+ L E
Sbjct: 449 LSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPE 508
Query: 500 LEQLNAELGLEPETPPKPPDAPPLGPDIHSLVQSDQEAQAVAEP 543
+ LE E+P PP+ P P + + + EA ++ P
Sbjct: 509 SSPFSP---LE-ESPLSPPEESPPSPALETPLSPPPEASPLSPP 548
Score = 32.0 bits (71), Expect = 1.5
Identities = 66/223 (29%), Positives = 80/223 (35%), Gaps = 37/223 (16%)
Query: 331 PQLTDVSEDLDQQSLPSEPEETLSRDLGEGEEGELAPPED---LLGRPQALSRQALDSEE 387
PQL SE P EP + EE L+P + L +P+ A+ E
Sbjct: 732 PQLCPRSEGPHLSPRPEEPHLS-----PRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEP 786
Query: 388 EEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVET-LSPETVSGGLTALP 446
A L LH SP C P E+ LSP++ L+ P
Sbjct: 787 HLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRP 846
Query: 447 --GTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEE--------EEALTTEDFE--L 494
LSP L P SP P P + P PAPEE E +L+ E L
Sbjct: 847 EESHLSPEL----EKPPLSPR--PEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPAL 900
Query: 495 LDQGE--LEQLNAELGLEPETPPK------PPDA--PPLGPDI 527
+ GE L L EL L P P PPD PPL P I
Sbjct: 901 SEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPII 943
Score = 29.3 bits (64), Expect = 9.6
Identities = 19/69 (27%), Positives = 23/69 (33%), Gaps = 5/69 (7%)
Query: 414 GAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGT-----LSPPLCLVGSDPAPSPSILP 468
GAG P + P G + P PGT P+ PS+ P
Sbjct: 2490 GAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKP 2549
Query: 469 PVPQDSPQP 477
PVPQ P
Sbjct: 2550 PVPQPGLPP 2558
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 48.5 bits (114), Expect = 2e-05
Identities = 62/265 (23%), Positives = 101/265 (38%), Gaps = 44/265 (16%)
Query: 262 KRQGKNAPPGGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESG 321
+ G+N+P ++++E+ + A VK+ A + ++ ++ AS E
Sbjct: 53 RSSGRNSPSAASTSSNDSKAETVKKSAK-----KVKEEASSPLKSNKRQREKVASDTEEA 107
Query: 322 GFSVSRATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEGEEGELAPPE-DLLGRPQALSR 380
+ S+ T Q ++ + + PSE E S +EG P + D R + S
Sbjct: 108 DRTSSKKTKTQ------EISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSI 161
Query: 381 QALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSG 440
+ E + D +A++ +L+ P A P GV +P
Sbjct: 162 PSPQDNESDSDSSAQQQMLQAQPP----------ALQAPTGVTPAPS------------- 198
Query: 441 GLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGEL 500
+A PGT P P P+PS PQ SP AP + +A T Q +
Sbjct: 199 --SAPPGTPQLPT------PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQ-QA 249
Query: 501 EQLNAELGLEPETPPKPPDAPPLGP 525
L+ + P PP P PPL P
Sbjct: 250 PALHPQRPPSPHPPPHPSPHPPLQP 274
Score = 34.3 bits (77), Expect = 0.30
Identities = 37/125 (29%), Positives = 46/125 (36%), Gaps = 34/125 (27%)
Query: 415 AGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCLVGSDP--APSPSILPP--- 469
A PP G+ P P V GG P ++PP C S P P S PP
Sbjct: 464 ASHPPTGLHQVAPQPPFAQHP-FVPGG----PPPITPPTCPSTSTPPAGPGTSAQPPCSG 518
Query: 470 -------VPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPP 522
+ S PLP + +E E LD E EPE+PP PP +P
Sbjct: 519 AAASGGSIAGGSSCPLPTVQIKE-------EALDDAE----------EPESPPPPPRSPS 561
Query: 523 LGPDI 527
P +
Sbjct: 562 PEPTV 566
Score = 29.6 bits (65), Expect = 7.4
Identities = 28/102 (27%), Positives = 37/102 (36%), Gaps = 11/102 (10%)
Query: 429 PVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSIL--------PPVPQDSPQPLPA 480
P L P T S G + P PPL G P P P L P PQ P A
Sbjct: 268 PHPPLQPLTGSAGQPSAPSHAQPPLH--GQGP-PGPHSLQAGPLLQHPGPPQPFGLPPQA 324
Query: 481 PEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPP 522
+ + L T L+ ++ L+ + PP+ PP
Sbjct: 325 SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 366
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 48.5 bits (114), Expect = 2e-05
Identities = 62/265 (23%), Positives = 101/265 (38%), Gaps = 44/265 (16%)
Query: 262 KRQGKNAPPGGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESG 321
+ G+N+P ++++E+ + A VK+ A + ++ ++ AS E
Sbjct: 607 RSSGRNSPSAASTSSNDSKAETVKKSAK-----KVKEEASSPLKSNKRQREKVASDTEEA 661
Query: 322 GFSVSRATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEGEEGELAPPE-DLLGRPQALSR 380
+ S+ T Q ++ + + PSE E S +EG P + D R + S
Sbjct: 662 DRTSSKKTKTQ------EISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSI 715
Query: 381 QALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSG 440
+ E + D +A++ +L+ P A P GV +P
Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPP----------ALQAPTGVTPAPS------------- 752
Query: 441 GLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGEL 500
+A PGT P P P+PS PQ SP AP + +A T Q +
Sbjct: 753 --SAPPGTPQLPT------PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQ-QA 803
Query: 501 EQLNAELGLEPETPPKPPDAPPLGP 525
L+ + P PP P PPL P
Sbjct: 804 PALHPQRPPSPHPPPHPSPHPPLQP 828
Score = 34.3 bits (77), Expect = 0.30
Identities = 37/125 (29%), Positives = 46/125 (36%), Gaps = 34/125 (27%)
Query: 415 AGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCLVGSDP--APSPSILPP--- 469
A PP G+ P P V GG P ++PP C S P P S PP
Sbjct: 1018 ASHPPTGLHQVAPQPPFAQHP-FVPGG----PPPITPPTCPSTSTPPAGPGTSAQPPCSG 1072
Query: 470 -------VPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPP 522
+ S PLP + +E E LD E EPE+PP PP +P
Sbjct: 1073 AAASGGSIAGGSSCPLPTVQIKE-------EALDDAE----------EPESPPPPPRSPS 1115
Query: 523 LGPDI 527
P +
Sbjct: 1116 PEPTV 1120
Score = 29.6 bits (65), Expect = 7.4
Identities = 28/102 (27%), Positives = 37/102 (36%), Gaps = 11/102 (10%)
Query: 429 PVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSIL--------PPVPQDSPQPLPA 480
P L P T S G + P PPL G P P P L P PQ P A
Sbjct: 822 PHPPLQPLTGSAGQPSAPSHAQPPLH--GQGP-PGPHSLQAGPLLQHPGPPQPFGLPPQA 878
Query: 481 PEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPP 522
+ + L T L+ ++ L+ + PP+ PP
Sbjct: 879 SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 920
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 48.5 bits (114), Expect = 2e-05
Identities = 62/265 (23%), Positives = 101/265 (38%), Gaps = 44/265 (16%)
Query: 262 KRQGKNAPPGGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESG 321
+ G+N+P ++++E+ + A VK+ A + ++ ++ AS E
Sbjct: 607 RSSGRNSPSAASTSSNDSKAETVKKSAK-----KVKEEASSPLKSNKRQREKVASDTEEA 661
Query: 322 GFSVSRATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEGEEGELAPPE-DLLGRPQALSR 380
+ S+ T Q ++ + + PSE E S +EG P + D R + S
Sbjct: 662 DRTSSKKTKTQ------EISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSI 715
Query: 381 QALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSG 440
+ E + D +A++ +L+ P A P GV +P
Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPP----------ALQAPTGVTPAPS------------- 752
Query: 441 GLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGEL 500
+A PGT P P P+PS PQ SP AP + +A T Q +
Sbjct: 753 --SAPPGTPQLPT------PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQ-QA 803
Query: 501 EQLNAELGLEPETPPKPPDAPPLGP 525
L+ + P PP P PPL P
Sbjct: 804 PALHPQRPPSPHPPPHPSPHPPLQP 828
Score = 34.3 bits (77), Expect = 0.30
Identities = 37/125 (29%), Positives = 46/125 (36%), Gaps = 34/125 (27%)
Query: 415 AGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCLVGSDP--APSPSILPP--- 469
A PP G+ P P V GG P ++PP C S P P S PP
Sbjct: 1018 ASHPPTGLHQVAPQPPFAQHP-FVPGG----PPPITPPTCPSTSTPPAGPGTSAQPPCSG 1072
Query: 470 -------VPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPP 522
+ S PLP + +E E LD E EPE+PP PP +P
Sbjct: 1073 AAASGGSIAGGSSCPLPTVQIKE-------EALDDAE----------EPESPPPPPRSPS 1115
Query: 523 LGPDI 527
P +
Sbjct: 1116 PEPTV 1120
Score = 29.6 bits (65), Expect = 7.4
Identities = 28/102 (27%), Positives = 37/102 (36%), Gaps = 11/102 (10%)
Query: 429 PVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSIL--------PPVPQDSPQPLPA 480
P L P T S G + P PPL G P P P L P PQ P A
Sbjct: 822 PHPPLQPLTGSAGQPSAPSHAQPPLH--GQGP-PGPHSLQAGPLLQHPGPPQPFGLPPQA 878
Query: 481 PEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPP 522
+ + L T L+ ++ L+ + PP+ PP
Sbjct: 879 SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 920
>gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]
Length = 374
Score = 47.8 bits (112), Expect = 3e-05
Identities = 38/107 (35%), Positives = 47/107 (43%), Gaps = 16/107 (14%)
Query: 427 GGPVETLSPETVSGGLTALP------GTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPA 480
G P +P + + A P G PP L G D P +LPP P P P+
Sbjct: 58 GRPSPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPP--PPPPVLL 115
Query: 481 PEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPPLGPDI 527
P EEEA L+ +LEQL+ L P PP PP AP GP +
Sbjct: 116 PSEEEAPAPMGASLI--ADLEQLH----LSP--PPPPPQAPAEGPSV 154
>gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]
Length = 373
Score = 47.8 bits (112), Expect = 3e-05
Identities = 38/107 (35%), Positives = 47/107 (43%), Gaps = 16/107 (14%)
Query: 427 GGPVETLSPETVSGGLTALP------GTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPA 480
G P +P + + A P G PP L G D P +LPP P P P+
Sbjct: 58 GRPSPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPP--PPPPVLL 115
Query: 481 PEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPPLGPDI 527
P EEEA L+ +LEQL+ L P PP PP AP GP +
Sbjct: 116 PSEEEAPAPMGASLI--ADLEQLH----LSP--PPPPPQAPAEGPSV 154
>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
Length = 1444
Score = 47.4 bits (111), Expect = 3e-05
Identities = 64/268 (23%), Positives = 100/268 (37%), Gaps = 26/268 (9%)
Query: 270 PGGDEPL-AETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGGFSVSRA 328
P ++PL AET + S + AG V + + + LS E + LE
Sbjct: 536 PEEEKPLGAETSAASVPKKAGLEDAKAVPEAPGTVECSKG-LSQEPGAHLEE-------K 587
Query: 329 TTPQLTDVSEDLDQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALDSEEE 388
TP+ + S+ L++ PE+ + EG E L P+A + L E +
Sbjct: 588 KTPESSLSSQHLNELEKRPNPEKVVE----EGREAGEMESSTLQESPRARAEAVLLHEMD 643
Query: 389 EEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLS-----PETVSGGLT 443
E+D+A + L + + + PP +K SP P+ S P G L
Sbjct: 644 EDDLANALIWPEIQQELKIIESEEELSSLPPPALKTSPIQPILESSLGPFIPSEPPGSLP 703
Query: 444 --ALPGTLSPPLCLVGSDPA--PSPSILPPVPQDSPQPLPAPEEEEA----LTTEDFELL 495
+ P +S PL + DPA + ++ P+P + A L FE
Sbjct: 704 CGSFPAPVSTPLEVWTRDPANQSTQGASTAASREKPEPEQGLHPDLASLAPLEIVPFEKA 763
Query: 496 DQGELEQLNAELGLEPETPPKPPDAPPL 523
++ L P PP PP PL
Sbjct: 764 SPQATVEVGGPGNLSPPLPPAPPPPTPL 791
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 46.2 bits (108), Expect = 8e-05
Identities = 64/265 (24%), Positives = 95/265 (35%), Gaps = 30/265 (11%)
Query: 269 PPGGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGGFSVSRA 328
PP DE +T+ + A S + + + + + + DEE E +
Sbjct: 941 PPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREE-----AVD 995
Query: 329 TTPQLTDVSEDLDQQSLPSEPEETLSRDLGEG------EEGELAPPEDLLGRPQALSRQA 382
TT + T+VS+ D++S S + GE E + + S +
Sbjct: 996 TTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSS 1055
Query: 383 LDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGG- 441
SE ED +E L S A PP V PVE PE V+G
Sbjct: 1056 SSSESSSEDEEEEERPAALPS-----------ASPPPREVPVPTPAPVEVPVPERVAGSP 1104
Query: 442 LTALPGTLSPPLCLVG--SDPAPSPSILPPVPQDSPQ-PLPAPEEEEALTTEDFELLDQG 498
+T LP + P G + PS + PP P P P P P+E + LL
Sbjct: 1105 VTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDER---PSSPIPLLPPP 1161
Query: 499 ELEQLNAEL-GLEPETPPKPPDAPP 522
+ + +E P+PP A P
Sbjct: 1162 KKRRKTVSFSAIEVVPAPEPPPATP 1186
Score = 38.5 bits (88), Expect = 0.016
Identities = 49/197 (24%), Positives = 68/197 (34%), Gaps = 22/197 (11%)
Query: 344 SLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSR-----QALDSEEEEEDVAAKETL 398
+L SE EE E +E + E+ R +A+ + D E+EE D ++K +L
Sbjct: 960 ALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSL 1019
Query: 399 LRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGL--------TALPGTLS 450
S + + + S S + S + S ALP
Sbjct: 1020 YADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASP 1079
Query: 451 PPLCLVGSDPAPSPSILPPVPQDSP-QPLPAPEEEEALTTEDFELLDQGELEQLNAELGL 509
PP + PAP +P SP PLP E A G E+ L
Sbjct: 1080 PPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPA--------GPTEESPPSAPL 1131
Query: 510 EPETPPKPPDAPPLGPD 526
P PP P AP PD
Sbjct: 1132 RPPEPPAGPPAPAPRPD 1148
Score = 35.8 bits (81), Expect = 0.10
Identities = 66/290 (22%), Positives = 95/290 (32%), Gaps = 30/290 (10%)
Query: 262 KRQGKNAPPGGDEPLAETESES-EAELAGFSPVVDVKKTALALAITDSELSDEEASILES 320
+R + PPG P AE +E + P + T SE E E
Sbjct: 385 RRATREEPPGA--PFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPP--EP 440
Query: 321 GGFSVSRATTPQLTDVSEDLDQQSLPSEPE-------ETLSRDLGEGEEGELAPPEDLLG 373
GG +P+ E++ P+ P ET + + + L ++L
Sbjct: 441 GGGGGGGGPSPE----REEVRTSPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLL 496
Query: 374 RPQALSRQALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPP-------DGVKCSP 426
+ Q L S+ EEE+ + L + + +G +PP D
Sbjct: 497 KEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGS 556
Query: 427 GGPVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEEEA 486
G P T +G A P + + + D SP P PQ P P P P
Sbjct: 557 GEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPP 616
Query: 487 LTTEDFELLDQGELEQLNAE-LGLEPETPPKP--PDAPPLGPDIHSLVQS 533
L G A L P+ PP P P PP P I+ V S
Sbjct: 617 YLAS----LPLGYPPHQPAYLLPPRPDGPPPPEYPPPPPPPPHIYDFVNS 662
Score = 31.2 bits (69), Expect = 2.5
Identities = 41/168 (24%), Positives = 57/168 (33%), Gaps = 9/168 (5%)
Query: 360 GEEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPP 419
G E +LA DL P AL + E+ E + R L + N A +
Sbjct: 1248 GTEVDLAVLADLALTPARRGLPALPAVEDSEATETSDEAERPRPLLSHILLEHNYALA-- 1305
Query: 420 DGVKCSPGGP-VETLSPETVSGGLTALPG--TLSPPLCLVGSDPAPSPSILPPVPQDSPQ 476
VK +P P + P L + P L P +V P P L ++ +
Sbjct: 1306 --VKPTPPAPALRPPEPVPAPAALFSSPADEVLEAPEVVVAEAEEPKPQQLQQQREEGEE 1363
Query: 477 PLPAPEEEEALTTEDFELLDQGE--LEQLNAELGLEPETPPKPPDAPP 522
EEE + D GE L + + PP PP PP
Sbjct: 1364 EGEEEGEEEEEESSDSSSSSDGEGALRRRSLRSHARRRRPPPPPPPPP 1411
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 46.2 bits (108), Expect = 8e-05
Identities = 79/328 (24%), Positives = 129/328 (39%), Gaps = 35/328 (10%)
Query: 222 LVVYHELIQRMY--TRLEPLLMQLDYSMKA--EANALHHKHDKRKRQGKNAPPGGDEPLA 277
L V H+ ++ + T++E +++ ++ A E A+ K +K++ +E
Sbjct: 446 LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKE--------AAEEKEE 497
Query: 278 ETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGGFSVSRATTPQLTDVS 337
E E+E E A SPV K TA + + E +EE E + D
Sbjct: 498 EPEAEEEEVAAKKSPV---KATAPEVKEEEGEKEEEEGQEEE------------EEEDEG 542
Query: 338 EDLDQ-QSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKE 396
DQ + SE E + ++ GE EEGE + +A +++ EE+ E+VA KE
Sbjct: 543 AKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAE---GEEAEAKEEKKVEEKSEEVATKE 599
Query: 397 TLLRLSSPLHFVNTHFNGAGSPPD--GVKCSPGGPVETLSPETVSGGLTALPGTLSPPLC 454
L+ + SP + G P PVE V G P
Sbjct: 600 ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS 659
Query: 455 LVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETP 514
V + SP PV + + P+P EEA + + +Q E E+ + + E
Sbjct: 660 PV-EEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKV 718
Query: 515 PKPPDAPPLGPDIHSLVQSDQEAQAVAE 542
K + P P+ +S + +AVAE
Sbjct: 719 EKKEEKPKDVPE-KKKAESPVKEEAVAE 745
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 46.2 bits (108), Expect = 8e-05
Identities = 79/328 (24%), Positives = 129/328 (39%), Gaps = 35/328 (10%)
Query: 222 LVVYHELIQRMY--TRLEPLLMQLDYSMKA--EANALHHKHDKRKRQGKNAPPGGDEPLA 277
L V H+ ++ + T++E +++ ++ A E A+ K +K++ +E
Sbjct: 70 LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKE--------AAEEKEE 121
Query: 278 ETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGGFSVSRATTPQLTDVS 337
E E+E E A SPV K TA + + E +EE E + D
Sbjct: 122 EPEAEEEEVAAKKSPV---KATAPEVKEEEGEKEEEEGQEEE------------EEEDEG 166
Query: 338 EDLDQ-QSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKE 396
DQ + SE E + ++ GE EEGE + +A +++ EE+ E+VA KE
Sbjct: 167 AKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAE---GEEAEAKEEKKVEEKSEEVATKE 223
Query: 397 TLLRLSSPLHFVNTHFNGAGSPPD--GVKCSPGGPVETLSPETVSGGLTALPGTLSPPLC 454
L+ + SP + G P PVE V G P
Sbjct: 224 ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS 283
Query: 455 LVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETP 514
V + SP PV + + P+P EEA + + +Q E E+ + + E
Sbjct: 284 PV-EEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKV 342
Query: 515 PKPPDAPPLGPDIHSLVQSDQEAQAVAE 542
K + P P+ +S + +AVAE
Sbjct: 343 EKKEEKPKDVPE-KKKAESPVKEEAVAE 369
>gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]
Length = 1388
Score = 45.4 bits (106), Expect = 1e-04
Identities = 73/270 (27%), Positives = 114/270 (42%), Gaps = 37/270 (13%)
Query: 274 EPLAETESESEAELAGFSPVVDVKKTALALA-ITDSELSDEEASILESGGFSVSRATTPQ 332
+P+ ++ S + A L + ++ TA LA + S + EAS + +GG ++S +T
Sbjct: 336 DPITDSGSGAGAFL-DIAEEKNLAATAAGLAEVPISTAGEAEASSVPTGGPTLSMSTENP 394
Query: 333 LTDVSEDLDQQ----SLPSEPEETLSRDLGEGEEGELAPPE-DLLGRPQALSRQAL--DS 385
V+ D + + + E L+ GE E +AP E DL Q+L +A S
Sbjct: 395 EEGVTPGPDNEERLAATAAGEAEALASMPGEVEASGVAPGELDLSMSAQSLGEEATVGPS 454
Query: 386 EEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVE-TLSPETVSGGLTA 444
E+ AA T + LS+ F + +G P DG+ P+ T++PE +T+
Sbjct: 455 SEDSLTTAAAATEVSLST---FEDEEASGV--PTDGL-----APLTATMAPERA---VTS 501
Query: 445 LPG--------TLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLD 496
PG T PL G + + SP P P PLP E +T E +
Sbjct: 502 GPGDEEDLAAATTEEPLITAGGEESGSPP-----PDGPPLPLPTVAPERWITPAQREHVG 556
Query: 497 QGELEQLNAELGLEPETPPKPPD-APPLGP 525
E G E P PP+ + P+GP
Sbjct: 557 MKGQAGPKGEKGDAGEELPGPPEPSGPVGP 586
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 44.3 bits (103), Expect = 3e-04
Identities = 68/279 (24%), Positives = 102/279 (36%), Gaps = 31/279 (11%)
Query: 269 PPGGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGGFSVSRA 328
PP P +T + + SP + + LAL+ + S ++ + F
Sbjct: 375 PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434
Query: 329 TTPQLTDVSEDLDQQSLPSEP--EETLSRDLGEGEEGELAPPEDLLGRPQALSR-QALDS 385
Q + S + P P + LS + L+P L P + QAL S
Sbjct: 435 RQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSS 494
Query: 386 EEEEEDVAAKETLLRLSSPLHFVNTHFNGA-GSPPDGVKCSPGGPVETLSP---ETVSGG 441
A +L+ PL ++ + +PP + P + +L+P +T S
Sbjct: 495 LASHSPQAPLSSLIM--PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAP 552
Query: 442 LTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQP-------LPAPEEEEALTTEDFEL 494
LT P +PP PAP P PP P +P P P P+ AL + +
Sbjct: 553 LTT-PHLETPPC------PAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG 605
Query: 495 LDQGELEQLNAE-------LGLEP-ETPPKPPDAPPLGP 525
L L L L L P + PP PP +PPL P
Sbjct: 606 LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP 644
Score = 36.6 bits (83), Expect = 0.060
Identities = 54/199 (27%), Positives = 69/199 (34%), Gaps = 38/199 (19%)
Query: 343 QSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKETLLRLS 402
Q LPS P L+ PP PQA AL + A L L+
Sbjct: 604 QGLPSPPLSPLA-----------TPP------PQAPPXLALPPLQAPPSPPASPPLSPLA 646
Query: 403 SP---------LHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPL 453
+P +H + F+ SPP SP P + + A P +PPL
Sbjct: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP--PASPPVSPSATPPSQAPPSLAAPPL 704
Query: 454 CLVGSDPAP---SPSILPPVPQDSPQ----PLPAPEEEEALTTEDFELLDQGELEQLNAE 506
+ S PA SPS PP PQ P PL P A + L A
Sbjct: 705 QVPPSPPASPPMSPSATPP-PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAA 763
Query: 507 LGLEPETPPKPPDAPPLGP 525
L+ PP PP + P+ P
Sbjct: 764 PPLQ--VPPSPPASLPMSP 780
Score = 29.6 bits (65), Expect = 7.4
Identities = 22/66 (33%), Positives = 26/66 (39%), Gaps = 4/66 (6%)
Query: 417 SPPDGVKCSP-GGPVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSP 475
SPP + SP P P + L ALP SPP G P + LP P +P
Sbjct: 771 SPPASLPMSPLAKPPPQAPPALATPPLQALP---SPPASFPGQAPFSPSASLPMSPLATP 827
Query: 476 QPLPAP 481
P P
Sbjct: 828 PPQAPP 833
>gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
1 isoform c [Homo sapiens]
Length = 1450
Score = 43.5 bits (101), Expect = 5e-04
Identities = 39/126 (30%), Positives = 47/126 (37%), Gaps = 29/126 (23%)
Query: 426 PGGPVETLSPETVSGGLTALPG-----TLSPPLCLVG-SDPAPSPSI------------- 466
P P E L T GL A P + PP C S AP P +
Sbjct: 95 PATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELS 154
Query: 467 LPPVPQDSPQP-----LPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAP 521
+PPVP + P LP EEE L + L Q L P+ PP+PP P
Sbjct: 155 VPPVPPRTGPPRLLVSLPTKEEESLLPS-----LSSPPQPQSEEPLSTLPQGPPQPPSPP 209
Query: 522 PLGPDI 527
P P+I
Sbjct: 210 PCPPEI 215
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 43.5 bits (101), Expect = 5e-04
Identities = 63/222 (28%), Positives = 79/222 (35%), Gaps = 40/222 (18%)
Query: 346 PSEPEETLSRDLGEGEEGELAPPEDL-LGRPQALSRQALDSE------------EEEEDV 392
P+ P S G G E A E L LG P R LD E +EED
Sbjct: 1330 PAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKR--LDEELKRNLETLPSFSSDEEDS 1387
Query: 393 AAKETLLRLSSPLHFVNTHFNGAGSPP-DGVK--CSPGGPVETLSPETVSGGLTALPG-- 447
AK L+ S +++ + PP G K +P GP L+P G LPG
Sbjct: 1388 VAKNRDLQES-----ISSAISALDDPPLAGPKDTSTPDGP--PLAPAAAVPGPPPLPGLP 1440
Query: 448 ------TLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGELE 501
T PPL + P P+P PP P PQP P P + L+
Sbjct: 1441 SANSNGTPEPPL--LEEKPPPTP---PPAPTPQPQPPPPPPPPQPALPSPPPLV--APTP 1493
Query: 502 QLNAELGLEPETPPKPPDAPPLGPDIHSLVQSDQEAQAVAEP 543
L P PP P PP P + + + E A P
Sbjct: 1494 SSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSP 1535
Score = 37.7 bits (86), Expect = 0.027
Identities = 32/90 (35%), Positives = 38/90 (42%), Gaps = 13/90 (14%)
Query: 414 GAGSPPDGVKCSPGGP-----VETLSPETVSGGLTA-----LPGTLSP-PLCLVGSDPAP 462
GAG PP P GP PET GL LP T++ PL L+ S P
Sbjct: 977 GAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQ 1036
Query: 463 SPSILPPVPQDSPQPLPAPEEEEALTTEDF 492
+ PP P P P PA E + LT+ F
Sbjct: 1037 AAP--PPPPPPPPPPAPASEPKGGLTSPIF 1064
Score = 33.1 bits (74), Expect = 0.67
Identities = 67/280 (23%), Positives = 92/280 (32%), Gaps = 43/280 (15%)
Query: 268 APPGGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSE-LSDEEASILESGGFSVS 326
A PGG P AE + E + +T+ A + + +D + SGG
Sbjct: 626 AGPGG--PPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGP 683
Query: 327 RATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALDSE 386
T +L ED + L S + S D EG A E LGR + +
Sbjct: 684 PGTPYELA--KEDPQRYHLQSVIRTSASLD-----EGATAALELGLGRLKEKKKGPERGG 736
Query: 387 EEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGV---KCSPGGPVETLSPETVSGGLT 443
E E +A +S +H+ GAG+ G K P P S + GL
Sbjct: 737 ETPEGLA--------TSVVHY------GAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLL 782
Query: 444 ALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGELEQL 503
G PL L P PS+L P SP T D
Sbjct: 783 LEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRD------------ 830
Query: 504 NAELGLEPETPPKPPDAPPLGPDIHSLVQSDQEAQAVAEP 543
G PP PP PP+ + + ++S A P
Sbjct: 831 ----GAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSP 866
Score = 33.1 bits (74), Expect = 0.67
Identities = 31/98 (31%), Positives = 38/98 (38%), Gaps = 14/98 (14%)
Query: 413 NGAGSPPDGVKCSPGGP--VETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSILPP- 469
NG PP + P P T P+ P SPP + + +P P LPP
Sbjct: 1445 NGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPP 1504
Query: 470 ----VPQDSPQPLPA-------PEEEEALTTEDFELLD 496
+P P P PA PEE A + ED EL D
Sbjct: 1505 PPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPD 1542
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 43.1 bits (100), Expect = 6e-04
Identities = 41/132 (31%), Positives = 54/132 (40%), Gaps = 25/132 (18%)
Query: 401 LSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLC----LV 456
L S H +GSPP P P++ P T SG L+++PG +PP +V
Sbjct: 433 LGSDAHLPPPPTLSSGSPPQ-----PRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVV 487
Query: 457 GSDPAPSPS-----------ILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNA 505
S SPS LPP+ P P+PE+ AL+ F G L L
Sbjct: 488 PSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGF----PGMLGALPL 543
Query: 506 ELGLEPETPPKP 517
L L + PP P
Sbjct: 544 PLSL-GQPPPSP 554
Score = 30.4 bits (67), Expect = 4.3
Identities = 44/156 (28%), Positives = 63/156 (40%), Gaps = 27/156 (17%)
Query: 392 VAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCS---PGGPVETLSPETVSGGLTAL--- 445
++A TL+ L+S L T +G+PP S PG P +++ T G ++L
Sbjct: 667 LSAPPTLIALNSAL-LAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKA 725
Query: 446 -------PGTLSPPL--CLVG------SDPAPSPSILPPVPQDSPQPLPAPEEEEALTTE 490
P LSP L L+G S P PS+L P P PL + + L
Sbjct: 726 PSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQP-----PGPLLSGQLGLQLLPG 780
Query: 491 DFELLDQGELEQLNAELGLEPETPPKPPDAPPLGPD 526
E A L + PP+ P+AP L P+
Sbjct: 781 GGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPE 816
Score = 30.0 bits (66), Expect = 5.6
Identities = 33/106 (31%), Positives = 41/106 (38%), Gaps = 13/106 (12%)
Query: 427 GGPVETLSPE--TVSGGLTAL--PGTLSPPLCLVGSDPAPS-----PSILPPVPQDSPQP 477
GGP +L PE +VS L PG L PP +DP PS P LP SP P
Sbjct: 159 GGP-GSLPPEPPSVSQAFPTLAGPGGLFPPRL---ADPVPSGGSSSPRFLPRGNAPSPAP 214
Query: 478 LPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPPL 523
P P + ++ + L + P PP PPL
Sbjct: 215 PPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPL 260
Score = 30.0 bits (66), Expect = 5.6
Identities = 23/67 (34%), Positives = 26/67 (38%), Gaps = 11/67 (16%)
Query: 414 GAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSILPPVPQD 473
G PP+ + PGGP L+P G P LV S P PS L P P
Sbjct: 568 GGQPPPEPLLPPPGGPGPPLAPGEPEG-----------PSLLVASLLPPPPSDLLPPPSA 616
Query: 474 SPQPLPA 480
P L A
Sbjct: 617 PPSNLLA 623
>gi|223633941 hypothetical protein LOC389730 [Homo sapiens]
Length = 1343
Score = 42.4 bits (98), Expect = 0.001
Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 30/208 (14%)
Query: 341 DQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALD-----SEEEEEDVAAK 395
+ L S+ + L L +G+ G+L+ P+ P + +A D S E ED A
Sbjct: 93 ETSDLLSQLQSLLGPHLDKGDFGQLSGPDP----PGEVGERAPDGASQSSHEPMEDAAP- 147
Query: 396 ETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCL 455
+ SPL + PD P T SP ++ +++L + P L
Sbjct: 148 -----ILSPL-----------ASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSL 191
Query: 456 VGSDPAPSPSILPPVPQDSPQPL----PAPEEEEALTTEDFELLDQGELEQLNAELGLEP 511
P+P P L P P +P PL P P+ A D L+ + + LG P
Sbjct: 192 PLEHPSPEPPALFPHPPHTPDPLACSPPPPKGFTAPPLRDSTLITPSHCDSVALPLGTVP 251
Query: 512 ETPPKPPDAPPLGPDIHSLVQSDQEAQA 539
++ D P I L S+ A
Sbjct: 252 QSLSPHEDLVASVPAISGLGGSNSHVSA 279
>gi|91206406 hypothetical protein LOC642265 [Homo sapiens]
Length = 1347
Score = 42.4 bits (98), Expect = 0.001
Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 30/208 (14%)
Query: 341 DQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALD-----SEEEEEDVAAK 395
+ L S+ + L L +G+ G+L+ P+ P + +A D S E ED A
Sbjct: 93 ETSDLLSQLQSLLGPHLDKGDFGQLSGPDP----PGEVGERAPDGASQSSHEPMEDAAP- 147
Query: 396 ETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCL 455
+ SPL + PD P T SP ++ +++L + P L
Sbjct: 148 -----ILSPL-----------ASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSL 191
Query: 456 VGSDPAPSPSILPPVPQDSPQPL----PAPEEEEALTTEDFELLDQGELEQLNAELGLEP 511
P+P P L P P +P PL P P+ A D L+ + + LG P
Sbjct: 192 PLEHPSPEPPALFPHPPHTPDPLACSPPPPKGFTAPPLRDSTLITPSHCDSVALPLGTVP 251
Query: 512 ETPPKPPDAPPLGPDIHSLVQSDQEAQA 539
++ D P I L S+ A
Sbjct: 252 QSLSPHEDLVASVPAISGLGGSNSHVSA 279
>gi|146231958 hypothetical protein LOC647060 [Homo sapiens]
Length = 1347
Score = 42.4 bits (98), Expect = 0.001
Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 30/208 (14%)
Query: 341 DQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALD-----SEEEEEDVAAK 395
+ L S+ + L L +G+ G+L+ P+ P + +A D S E ED A
Sbjct: 93 ETSDLLSQLQSLLGPHLDKGDFGQLSGPDP----PGEVGERAPDGASQSSHEPMEDAAP- 147
Query: 396 ETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCL 455
+ SPL + PD P T SP ++ +++L + P L
Sbjct: 148 -----ILSPL-----------ASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSL 191
Query: 456 VGSDPAPSPSILPPVPQDSPQPL----PAPEEEEALTTEDFELLDQGELEQLNAELGLEP 511
P+P P L P P +P PL P P+ A D L+ + + LG P
Sbjct: 192 PLEHPSPEPPALFPHPPHTPDPLACSPPPPKGFTAPPLRDSTLITPSHCDSVALPLGTVP 251
Query: 512 ETPPKPPDAPPLGPDIHSLVQSDQEAQA 539
++ D P I L S+ A
Sbjct: 252 QSLSPHEDLVASVPAISGLGGSNSHVSA 279
>gi|24308007 ADP-ribosylation factor-like 6 interacting protein
[Homo sapiens]
Length = 203
Score = 42.4 bits (98), Expect = 0.001
Identities = 42/193 (21%), Positives = 79/193 (40%), Gaps = 16/193 (8%)
Query: 39 AEEEAATAEAVGRLATTLWLRLRGWEAVLAAAQRLLVWEKPLHSLVTAAALNGLFWLLSS 98
AE + + + +L +L+GW V+ A ++L WE+ ++ +F ++
Sbjct: 2 AEGDNRSTNLLAAETASLEEQLQGWGEVMLMADKVLRWERAWFPPAIMGVVSLVFLII-- 59
Query: 99 SSLRPFFLLSVSLLAYF--LLDLWQPRFLPDVSASSPEEPHSDSEGAGSGARPHLLSVPE 156
L P L VS F L D P P + S+ R H E
Sbjct: 60 YYLDPSVLSGVSCFVMFLCLADYLVPILAPRIFGSNKWTTEQQQ-------RFH-----E 107
Query: 157 LCRYLAESWLTFQIHLQELLQYKRQNPAQFCVRVCSGCAVLAVLGHYVPGIMISYIVLLS 216
+C L ++ + L K + P + + + A +A +G V ++++Y+++ S
Sbjct: 108 ICSNLVKTRRRAVGWWKRLFTLKEEKPKMYFMTMIVSLAAVAWVGQQVHNLLLTYLIVTS 167
Query: 217 ILLWPLVVYHELI 229
+LL P + H +I
Sbjct: 168 LLLLPGLNQHGII 180
>gi|169174618 PREDICTED: family with sequence similarity 75, member
A4 isoform 2 [Homo sapiens]
Length = 1272
Score = 42.0 bits (97), Expect = 0.001
Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 30/208 (14%)
Query: 341 DQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALD-----SEEEEEDVAAK 395
+ L S+ + L L +G+ G+L+ P+ P + +A D S E ED A
Sbjct: 18 ETSDLLSQLQSLLGPHLDKGDFGQLSGPDP----PGEVGERAPDGASQSSHEPMEDAAP- 72
Query: 396 ETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCL 455
+ SPL + PD P T SP ++ +++L + P L
Sbjct: 73 -----ILSPL-----------ASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSL 116
Query: 456 VGSDPAPSPSILPPVPQDSPQP----LPAPEEEEALTTEDFELLDQGELEQLNAELGLEP 511
P+P P L P P +P P LP P+ A D L+ + + LG P
Sbjct: 117 PLEHPSPEPPALFPHPPHTPDPLACSLPPPKGFTAPPLRDSTLITPSHCDSVAFPLGTVP 176
Query: 512 ETPPKPPDAPPLGPDIHSLVQSDQEAQA 539
++ D P I L S+ A
Sbjct: 177 QSLSPHEDLVASVPAISGLGGSNSHVSA 204
>gi|239743732 PREDICTED: family with sequence similarity 75, member
A4 isoform 1 [Homo sapiens]
Length = 1361
Score = 42.0 bits (97), Expect = 0.001
Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 30/208 (14%)
Query: 341 DQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALD-----SEEEEEDVAAK 395
+ L S+ + L L +G+ G+L+ P+ P + +A D S E ED A
Sbjct: 107 ETSDLLSQLQSLLGPHLDKGDFGQLSGPDP----PGEVGERAPDGASQSSHEPMEDAAP- 161
Query: 396 ETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCL 455
+ SPL + PD P T SP ++ +++L + P L
Sbjct: 162 -----ILSPL-----------ASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSL 205
Query: 456 VGSDPAPSPSILPPVPQDSPQP----LPAPEEEEALTTEDFELLDQGELEQLNAELGLEP 511
P+P P L P P +P P LP P+ A D L+ + + LG P
Sbjct: 206 PLEHPSPEPPALFPHPPHTPDPLACSLPPPKGFTAPPLRDSTLITPSHCDSVAFPLGTVP 265
Query: 512 ETPPKPPDAPPLGPDIHSLVQSDQEAQA 539
++ D P I L S+ A
Sbjct: 266 QSLSPHEDLVASVPAISGLGGSNSHVSA 293
>gi|153791826 hypothetical protein LOC26165 [Homo sapiens]
Length = 1347
Score = 42.0 bits (97), Expect = 0.001
Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 30/208 (14%)
Query: 341 DQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALD-----SEEEEEDVAAK 395
+ L S+ + L L +G+ G+L+ P+ P + +A D S E ED A
Sbjct: 93 ETSDLLSQLQSLLGPHLDKGDFGQLSGPDP----PGEVGERAPDGASQSSHEPMEDAAP- 147
Query: 396 ETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCL 455
+ SPL + PD P T SP ++ +++L + P L
Sbjct: 148 -----ILSPL-----------ASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSL 191
Query: 456 VGSDPAPSPSILPPVPQDSPQP----LPAPEEEEALTTEDFELLDQGELEQLNAELGLEP 511
P+P P L P P +P P LP P+ A D L+ + + LG P
Sbjct: 192 PLEHPSPEPPALFPHPPHTPDPLACSLPPPKGFTAPPLRDSTLITPSHCDSVAFPLGTVP 251
Query: 512 ETPPKPPDAPPLGPDIHSLVQSDQEAQA 539
++ D P I L S+ A
Sbjct: 252 QSLSPHEDLVASVPAISGLGGSNSHVSA 279
>gi|133892686 hypothetical protein LOC727830 [Homo sapiens]
Length = 1347
Score = 42.0 bits (97), Expect = 0.001
Identities = 50/208 (24%), Positives = 77/208 (37%), Gaps = 30/208 (14%)
Query: 341 DQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALD-----SEEEEEDVAAK 395
+ L S+ + L L +G+ G+L+ P+ P + +A D S E ED A
Sbjct: 93 ETSDLLSQLQSLLGPHLDKGDFGQLSGPDP----PGEVGERAPDGASQSSHEPMEDAAPI 148
Query: 396 ETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCL 455
+LL + PD P T SP ++ +++L + P L
Sbjct: 149 LSLL-----------------ASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSL 191
Query: 456 VGSDPAPSPSILPPVPQDSPQP----LPAPEEEEALTTEDFELLDQGELEQLNAELGLEP 511
P+P P L P P +P P LP P+ A D L+ + + LG P
Sbjct: 192 PLEHPSPEPPALFPHPPHTPDPLACSLPPPKGFTAPPLRDSTLITPSHCDSVALPLGTVP 251
Query: 512 ETPPKPPDAPPLGPDIHSLVQSDQEAQA 539
++ D P I L S+ A
Sbjct: 252 QSLSPHEDLVASVPAISGLGGSNSHVSA 279
>gi|165377334 hypothetical protein LOC727905 [Homo sapiens]
Length = 1347
Score = 42.0 bits (97), Expect = 0.001
Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 30/208 (14%)
Query: 341 DQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALD-----SEEEEEDVAAK 395
+ L S+ + L L +G+ G+L+ P+ P + +A D S E ED A
Sbjct: 93 ETSDLLSQLQSLLGPHLDKGDFGQLSGPDP----PGEVGERAPDGASQSSHEPMEDAAP- 147
Query: 396 ETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCL 455
+ SPL + PD P T SP ++ +++L + P L
Sbjct: 148 -----ILSPL-----------ASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSL 191
Query: 456 VGSDPAPSPSILPPVPQDSPQP----LPAPEEEEALTTEDFELLDQGELEQLNAELGLEP 511
P+P P L P P +P P LP P+ A D L+ + + LG P
Sbjct: 192 PLEHPSPEPPALFPHPPHTPDPLACSLPPPKGFTAPPLRDSTLITPSHCDSVAFPLGTVP 251
Query: 512 ETPPKPPDAPPLGPDIHSLVQSDQEAQA 539
++ D P I L S+ A
Sbjct: 252 QSLSPHEDLVASVPAISGLGGSNSHVSA 279
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 41.2 bits (95), Expect = 0.002
Identities = 59/248 (23%), Positives = 82/248 (33%), Gaps = 45/248 (18%)
Query: 309 ELSDEEASILESGGFSVSRATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEGEE--GELA 366
EL ++ A + E + A + ++E Q S + ETL E
Sbjct: 403 ELQEQVALLTER----LRDAENESMAKIAELEKQLSQARKELETLRERFSESTAMGASRR 458
Query: 367 PPEDLLGRPQALSR-QALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCS 425
PPE P A +R AL+ + EE + +LR + +P G +
Sbjct: 459 PPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPT 518
Query: 426 PGGPVETLSPETVSGGLTA----------LPGTLSPPLCLVGSDP-------APSPSILP 468
PG P + SP+ A LPG SP + P +P P P
Sbjct: 519 PGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAP 578
Query: 469 PVPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPPLGPDIH 528
P+P D P P P P P PP PP PP G
Sbjct: 579 PLPGDLPPPPPPPPPPPGTD---------------------GPVPPPPPPPPPPPGGPPD 617
Query: 529 SLVQSDQE 536
+L + D E
Sbjct: 618 ALGRRDSE 625
>gi|83367077 mucin 16 [Homo sapiens]
Length = 14507
Score = 40.8 bits (94), Expect = 0.003
Identities = 62/257 (24%), Positives = 89/257 (34%), Gaps = 25/257 (9%)
Query: 265 GKNAPPGGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGGFS 324
G P G L T + S+ S + K +L + ++ +S+E +S E
Sbjct: 9255 GITYPTGDTNVLTSTPAFSDT-----SRIQTKSKLSLTPGLMETSISEETSSATEKSTV- 9308
Query: 325 VSRATTPQLTDVSE----DLDQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSR 380
+S T T+VS + S+P + T+S D ++ P L R ++
Sbjct: 9309 LSSVPTGATTEVSRTEAISSSRTSIPGPAQSTMSSDTSMETITRISTP---LTRKESTDM 9365
Query: 381 QALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSG 440
+ L SS + TH P V +P + PE VS
Sbjct: 9366 AITPKTGPSGATSQGTFTLDSSSTASWPGTHSATTQRFPQSVVTTP----MSRGPEDVSW 9421
Query: 441 GLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGEL 500
SPP LV S SPS L P S P P T F +
Sbjct: 9422 PSPLSVEKNSPPSSLVSSSSVTSPSPLYSTPSGSSHSSPVP------VTSLFTSIMMKAT 9475
Query: 501 EQLNAELGLEPETPPKP 517
+ L+A LEPET P
Sbjct: 9476 DMLDA--SLEPETTSAP 9490
Score = 30.4 bits (67), Expect = 4.3
Identities = 47/215 (21%), Positives = 76/215 (35%), Gaps = 19/215 (8%)
Query: 275 PLAETESESEAELAGFSP-----VVDVKKTALALAITDSELSDEEASILESGGFSVSRAT 329
P+A T + ++ +P ++ ++L + + S E +S E S+S
Sbjct: 8675 PMATTSTLGNTSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATERSA-SLSGMP 8733
Query: 330 TPQLTDVSE----DLDQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQ-ALSRQALD 384
T T VS L + S P + T+S ++ ++ P G + ++ +
Sbjct: 8734 TGATTKVSRTEALSLGRTSTPGPAQSTISPEISTETITRISTPLTTTGSAEMTITPKTGH 8793
Query: 385 SEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTA 444
S + +T R S P TH P +P + PE VS
Sbjct: 8794 SGASSQGTFTLDTSSRASWP----GTHSAATHRSPHSGMTTP----MSRGPEDVSWPSRP 8845
Query: 445 LPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLP 479
SPP LV SPS L P +S P
Sbjct: 8846 SVEKTSPPSSLVSLSAVTSPSPLYSTPSESSHSSP 8880
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.132 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,808,009
Number of Sequences: 37866
Number of extensions: 1498974
Number of successful extensions: 15047
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 171
Number of HSP's successfully gapped in prelim test: 610
Number of HSP's that attempted gapping in prelim test: 10821
Number of HSP's gapped (non-prelim): 3719
length of query: 543
length of database: 18,247,518
effective HSP length: 107
effective length of query: 436
effective length of database: 14,195,856
effective search space: 6189393216
effective search space used: 6189393216
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.