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Search of human proteins with 100815975
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|100815975 CTD (carboxy-terminal domain, RNA polymerase II,
polypeptide A) small phosphatase like 2 [Homo sapiens]
(466 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|100815975 CTD (carboxy-terminal domain, RNA polymerase II, po... 930 0.0
gi|56549681 small CTD phosphatase 3 isoform 2 [Homo sapiens] 160 2e-39
gi|56549683 small CTD phosphatase 3 isoform 1 [Homo sapiens] 156 4e-38
gi|32813443 CTD (carboxy-terminal domain, RNA polymerase II, pol... 153 3e-37
gi|10864009 CTD (carboxy-terminal domain, RNA polymerase II, pol... 152 6e-37
gi|93004102 nuclear LIM interactor-interacting factor 2 [Homo sa... 151 1e-36
gi|219555649 dullard homolog [Homo sapiens] 123 4e-28
gi|31542547 dullard homolog [Homo sapiens] 123 4e-28
gi|48526509 translocase of inner mitochondrial membrane 50 homol... 76 6e-14
gi|67188550 CTD (carboxy-terminal domain, RNA polymerase II, pol... 60 3e-09
gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II, pol... 60 3e-09
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 37 0.029
gi|7019499 peroxisome proliferator-activated receptor gamma, coa... 37 0.050
gi|8923040 CDKN2A interacting protein [Homo sapiens] 36 0.085
gi|87299628 biorientation of chromosomes in cell division 1-like... 36 0.085
gi|217330574 EH domain binding protein 1 isoform 3 [Homo sapiens] 35 0.11
gi|217330572 EH domain binding protein 1 isoform 3 [Homo sapiens] 35 0.11
gi|217330570 EH domain binding protein 1 isoform 2 [Homo sapiens] 35 0.11
gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens] 35 0.11
gi|114796630 homeodomain interacting protein kinase 3 isoform 2 ... 34 0.25
gi|50962882 G patch domain containing 8 [Homo sapiens] 34 0.25
gi|40806209 WW domain containing E3 ubiquitin protein ligase 2 i... 33 0.42
gi|40806207 WW domain containing E3 ubiquitin protein ligase 2 i... 33 0.42
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 33 0.55
gi|193083197 ubiquitin-like domain containing CTD phosphatase 1 ... 33 0.72
gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens] 32 0.94
gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens] 32 0.94
gi|114796624 homeodomain interacting protein kinase 3 isoform 1 ... 32 0.94
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] 32 1.6
gi|4557719 DNA ligase I [Homo sapiens] 32 1.6
>gi|100815975 CTD (carboxy-terminal domain, RNA polymerase II,
polypeptide A) small phosphatase like 2 [Homo sapiens]
Length = 466
Score = 930 bits (2403), Expect = 0.0
Identities = 466/466 (100%), Positives = 466/466 (100%)
Query: 1 MRLRTRKASQQSNQIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGST 60
MRLRTRKASQQSNQIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGST
Sbjct: 1 MRLRTRKASQQSNQIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGST 60
Query: 61 PKEERENPSKRSRIERDIDNNLITSTPRAGEKPNKQISRVRRKSQVNGEAGSYEMTNQHV 120
PKEERENPSKRSRIERDIDNNLITSTPRAGEKPNKQISRVRRKSQVNGEAGSYEMTNQHV
Sbjct: 61 PKEERENPSKRSRIERDIDNNLITSTPRAGEKPNKQISRVRRKSQVNGEAGSYEMTNQHV 120
Query: 121 KQNGKLEDNPSSGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLD 180
KQNGKLEDNPSSGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLD
Sbjct: 121 KQNGKLEDNPSSGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLD 180
Query: 181 MEQVDEITTSTTTSTNGAAYSNQAVQVRPSLNNGLEEAEETVNRDIPPLTAPVTPDSGYS 240
MEQVDEITTSTTTSTNGAAYSNQAVQVRPSLNNGLEEAEETVNRDIPPLTAPVTPDSGYS
Sbjct: 181 MEQVDEITTSTTTSTNGAAYSNQAVQVRPSLNNGLEEAEETVNRDIPPLTAPVTPDSGYS 240
Query: 241 SAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVH 300
SAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVH
Sbjct: 241 SAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVH 300
Query: 301 CSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLL 360
CSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLL
Sbjct: 301 CSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLL 360
Query: 361 NILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPI 420
NILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPI
Sbjct: 361 NILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPI 420
Query: 421 ESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD 466
ESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD
Sbjct: 421 ESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD 466
>gi|56549681 small CTD phosphatase 3 isoform 2 [Homo sapiens]
Length = 265
Score = 160 bits (405), Expect = 2e-39
Identities = 89/185 (48%), Positives = 117/185 (63%), Gaps = 7/185 (3%)
Query: 264 VPPLTEEQ--LNRKPALPLKTRSTP----EFSLVLDLDETLVHCSLNELEDAALTFPVLF 317
+PPL EE L + PA L T + +V+DLDETLVH S + +A PV
Sbjct: 66 LPPLVEENGGLQKPPAKYLLPEVTVLDYGKKCVVIDLDETLVHSSFKPISNADFIVPVEI 125
Query: 318 QDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFRE 377
I+QVYV RP EFL+RM Q++E +LFTAS YAD + ++LD + + R RLFRE
Sbjct: 126 DGTIHQVYVLKRPHVDEFLQRMGQLFECVLFTASLAKYADPVADLLD-RWGVFRARLFRE 184
Query: 378 HCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIP 437
CV +GNY+KDL+ LGR+LSK II+DNSP ++ + N +P++SWF D D ELL LIP
Sbjct: 185 SCVFHRGNYVKDLSRLGRELSKVIIVDNSPASYIFHPENAVPVQSWFDDMTDTELLDLIP 244
Query: 438 FLEKL 442
F E L
Sbjct: 245 FFEGL 249
>gi|56549683 small CTD phosphatase 3 isoform 1 [Homo sapiens]
Length = 276
Score = 156 bits (394), Expect = 4e-38
Identities = 79/153 (51%), Positives = 104/153 (67%), Gaps = 1/153 (0%)
Query: 290 LVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFT 349
+V+DLDETLVH S + +A PV I+QVYV RP EFL+RM Q++E +LFT
Sbjct: 109 VVIDLDETLVHSSFKPISNADFIVPVEIDGTIHQVYVLKRPHVDEFLQRMGQLFECVLFT 168
Query: 350 ASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQA 409
AS YAD + ++LD + + R RLFRE CV +GNY+KDL+ LGR+LSK II+DNSP +
Sbjct: 169 ASLAKYADPVADLLD-RWGVFRARLFRESCVFHRGNYVKDLSRLGRELSKVIIVDNSPAS 227
Query: 410 FAYQLSNGIPIESWFMDKNDNELLKLIPFLEKL 442
+ + N +P++SWF D D ELL LIPF E L
Sbjct: 228 YIFHPENAVPVQSWFDDMTDTELLDLIPFFEGL 260
>gi|32813443 CTD (carboxy-terminal domain, RNA polymerase II,
polypeptide A) small phosphatase 1 isoform 2 [Homo
sapiens]
Length = 260
Score = 153 bits (387), Expect = 3e-37
Identities = 80/189 (42%), Positives = 117/189 (61%), Gaps = 8/189 (4%)
Query: 266 PLTEEQLNRKPALPL-------KTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQ 318
PL E+ P P+ K + + + +V+DLDETLVH S + +A PV
Sbjct: 61 PLLVEENGAIPKTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEID 120
Query: 319 DVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREH 378
V++QVYV RP EFL+RM +++E +LFTAS YAD + ++LD K R RLFRE
Sbjct: 121 GVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLD-KWGAFRARLFRES 179
Query: 379 CVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPF 438
CV +GNY+KDL+ LGRDL + +I+DNSP ++ + N +P+ SWF + +D EL L+PF
Sbjct: 180 CVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPF 239
Query: 439 LEKLVELNE 447
E+L +++
Sbjct: 240 FEQLSRVDD 248
>gi|10864009 CTD (carboxy-terminal domain, RNA polymerase II,
polypeptide A) small phosphatase 1 isoform 1 [Homo
sapiens]
Length = 261
Score = 152 bits (384), Expect = 6e-37
Identities = 75/167 (44%), Positives = 110/167 (65%), Gaps = 1/167 (0%)
Query: 281 KTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMS 340
K + + + +V+DLDETLVH S + +A PV V++QVYV RP EFL+RM
Sbjct: 84 KAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMG 143
Query: 341 QMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKT 400
+++E +LFTAS YAD + ++LD K R RLFRE CV +GNY+KDL+ LGRDL +
Sbjct: 144 ELFECVLFTASLAKYADPVADLLD-KWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRV 202
Query: 401 IIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNE 447
+I+DNSP ++ + N +P+ SWF + +D EL L+PF E+L +++
Sbjct: 203 LILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPFFEQLSRVDD 249
>gi|93004102 nuclear LIM interactor-interacting factor 2 [Homo
sapiens]
Length = 271
Score = 151 bits (382), Expect = 1e-36
Identities = 80/179 (44%), Positives = 110/179 (61%), Gaps = 14/179 (7%)
Query: 264 VPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQ 323
+P +TEE R +V+DLDETLVH S + +A P+ + +Q
Sbjct: 91 LPEVTEEDQGR-------------ICVVIDLDETLVHSSFKPINNADFIVPIEIEGTTHQ 137
Query: 324 VYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQ 383
VYV RP+ EFL RM +++E +LFTAS YAD + ++LD + + R RLFRE CV Q
Sbjct: 138 VYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLD-RCGVFRARLFRESCVFHQ 196
Query: 384 GNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKL 442
G Y+KDL+ LGRDL KT+I+DNSP ++ + N +P++SWF D D ELL LIP E+L
Sbjct: 197 GCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMADTELLNLIPIFEEL 255
>gi|219555649 dullard homolog [Homo sapiens]
Length = 244
Score = 123 bits (308), Expect = 4e-28
Identities = 79/226 (34%), Positives = 116/226 (51%), Gaps = 18/226 (7%)
Query: 252 WEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFS------LVLDLDETLVHCSLNE 305
W F Y + + + + Q R LPL S + LVLDLDETL+H +
Sbjct: 21 WSFFI-YLLRRQIRTVIQYQTVRYDILPLSPVSRNRLAQVKRKILVLDLDETLIHSHHDG 79
Query: 306 LEDAALTFPVLFQDVIYQV---------YVRLRPFFREFLERMSQMYEIILFTASKKVYA 356
+ + P D I +V +V RP FLE +SQ YE+++FTAS ++Y
Sbjct: 80 VLRPTVR-PGTPPDFILKVVIDKHPVRFFVHKRPHVDFFLEVVSQWYELVVFTASMEIYG 138
Query: 357 DKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSN 416
+ + LD + +++ R +R+HC G+YIKDL+++ DLS +I+DNSP A+ N
Sbjct: 139 SAVADKLDNSRSILKRRYYRQHCTLELGSYIKDLSVVHSDLSSIVILDNSPGAYRSHPDN 198
Query: 417 GIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDL 462
IPI+SWF D +D LL L+P L+ L DVR + H L
Sbjct: 199 AIPIKSWFSDPSDTALLNLLPMLDAL-RFTADVRSVLSRNLHQHRL 243
>gi|31542547 dullard homolog [Homo sapiens]
Length = 244
Score = 123 bits (308), Expect = 4e-28
Identities = 79/226 (34%), Positives = 116/226 (51%), Gaps = 18/226 (7%)
Query: 252 WEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFS------LVLDLDETLVHCSLNE 305
W F Y + + + + Q R LPL S + LVLDLDETL+H +
Sbjct: 21 WSFFI-YLLRRQIRTVIQYQTVRYDILPLSPVSRNRLAQVKRKILVLDLDETLIHSHHDG 79
Query: 306 LEDAALTFPVLFQDVIYQV---------YVRLRPFFREFLERMSQMYEIILFTASKKVYA 356
+ + P D I +V +V RP FLE +SQ YE+++FTAS ++Y
Sbjct: 80 VLRPTVR-PGTPPDFILKVVIDKHPVRFFVHKRPHVDFFLEVVSQWYELVVFTASMEIYG 138
Query: 357 DKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSN 416
+ + LD + +++ R +R+HC G+YIKDL+++ DLS +I+DNSP A+ N
Sbjct: 139 SAVADKLDNSRSILKRRYYRQHCTLELGSYIKDLSVVHSDLSSIVILDNSPGAYRSHPDN 198
Query: 417 GIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDL 462
IPI+SWF D +D LL L+P L+ L DVR + H L
Sbjct: 199 AIPIKSWFSDPSDTALLNLLPMLDAL-RFTADVRSVLSRNLHQHRL 243
>gi|48526509 translocase of inner mitochondrial membrane 50 homolog
[Homo sapiens]
Length = 456
Score = 76.3 bits (186), Expect = 6e-14
Identities = 52/178 (29%), Positives = 94/178 (52%), Gaps = 20/178 (11%)
Query: 286 PEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEI 345
P ++LVL+L L+H + +L F+ RP ++++ +YEI
Sbjct: 249 PPYTLVLELTGVLLH------PEWSLATGWRFKK---------RPGIETLFQQLAPLYEI 293
Query: 346 ILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDN 405
++FT+ + A L++ +DP + +RLFR+ + G+++KD++ L RD ++ +++D
Sbjct: 294 VIFTSETGMTAFPLIDSVDPHG-FISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDC 352
Query: 406 SPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELN--EDVRPHIRDRFRLHD 461
+AF Q NG+ + W + +D LL L FL K + LN EDVR + + + L D
Sbjct: 353 KKEAFRLQPYNGVALRPWDGNSDDRVLLDLSAFL-KTIALNGVEDVRT-VLEHYALED 408
>gi|67188550 CTD (carboxy-terminal domain, RNA polymerase II,
polypeptide A) phosphatase, subunit 1 isoform FCP1b
[Homo sapiens]
Length = 867
Score = 60.5 bits (145), Expect = 3e-09
Identities = 37/114 (32%), Positives = 65/114 (57%), Gaps = 5/114 (4%)
Query: 270 EQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQ--VYVR 327
EQL R+ L + L++DLD+TL+H + + + FQ + ++ R
Sbjct: 167 EQLGREDQQRLHRNR--KLVLMVDLDQTLIHTTEQHCQQMSNKGIFHFQLGRGEPMLHTR 224
Query: 328 LRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHR-LFREHCV 380
LRP ++FLE+++++YE+ +FT ++YA + LDP+K+L HR L R+ C+
Sbjct: 225 LRPHCKDFLEKIAKLYELHVFTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECI 278
>gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II,
polypeptide A) phosphatase, subunit 1 isoform FCP1a
[Homo sapiens]
Length = 961
Score = 60.5 bits (145), Expect = 3e-09
Identities = 37/114 (32%), Positives = 65/114 (57%), Gaps = 5/114 (4%)
Query: 270 EQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQ--VYVR 327
EQL R+ L + L++DLD+TL+H + + + FQ + ++ R
Sbjct: 167 EQLGREDQQRLHRNR--KLVLMVDLDQTLIHTTEQHCQQMSNKGIFHFQLGRGEPMLHTR 224
Query: 328 LRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHR-LFREHCV 380
LRP ++FLE+++++YE+ +FT ++YA + LDP+K+L HR L R+ C+
Sbjct: 225 LRPHCKDFLEKIAKLYELHVFTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECI 278
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 37.4 bits (85), Expect = 0.029
Identities = 52/253 (20%), Positives = 92/253 (36%), Gaps = 38/253 (15%)
Query: 12 SNQIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTP----KEEREN 67
S ++ + + RKYSE SL + + S+ +K +G K+E+
Sbjct: 783 SKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNR 842
Query: 68 PSKRSRIERDIDNNLITSTPRAGEKPNKQISRVRRKSQVNGEAGSYEMTNQHVKQNGKLE 127
++S+ ER+ ++ + + S+ +RK+ + S + + V +N K +
Sbjct: 843 GEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKND 902
Query: 128 DNPSSGS--------------------PPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPG 167
+PSS P T P N ++K TS SDS G
Sbjct: 903 SHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEG 962
Query: 168 QAVEAE--------------EIVKQLDMEQVDEITTSTTTSTNGAAYSNQAVQVRPSLNN 213
+E E +K+ ++V E + A QA +P L
Sbjct: 963 SCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEF 1022
Query: 214 GLEEAEETVNRDI 226
G EE EE ++ +
Sbjct: 1023 GEEEEEEIDDKQV 1035
>gi|7019499 peroxisome proliferator-activated receptor gamma,
coactivator 1 alpha [Homo sapiens]
Length = 798
Score = 36.6 bits (83), Expect = 0.050
Identities = 42/181 (23%), Positives = 69/181 (38%), Gaps = 8/181 (4%)
Query: 5 TRKASQQSNQIQTQRTARAKR-KYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTPKE 63
+ KA Q + QR ++ KY +D P KP++N K T +
Sbjct: 190 SNKAKSICQQQKPQRRPCSELLKYLTTNDDPPH--TKPTENRNSSRDKCTSKKKSHTQSQ 247
Query: 64 ERENPSKRSRIERDIDNNLITSTPRAGEKPNKQISRVRRKSQVNGEAGSYEMTNQHVKQN 123
+ +K + + + + P+ NK I R +++G AG T K N
Sbjct: 248 SQHLQAKPTTLSLPLTPES-PNDPKGSPFENKTIERTL-SVELSGTAGLTPPTTPPHKAN 305
Query: 124 GKLEDNPSSGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQ 183
+DNP SP + T+ P + +GT G++S + E E+ QL
Sbjct: 306 ---QDNPFRASPKLKSSCKTVVPPPSKKPRYSESSGTQGNNSTKKGPEQSELYAQLSKSS 362
Query: 184 V 184
V
Sbjct: 363 V 363
>gi|8923040 CDKN2A interacting protein [Homo sapiens]
Length = 580
Score = 35.8 bits (81), Expect = 0.085
Identities = 49/228 (21%), Positives = 87/228 (38%), Gaps = 30/228 (13%)
Query: 8 ASQQSNQIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETG-----LLSSIKKFIKGSTPK 62
+SQ S+ + +Q T K SE E P K+ + L SS+ + ST
Sbjct: 211 SSQSSSSVSSQVTTAGSGKASEA--------EAPDKHGSASFVSLLKSSVNSHMTQSTDS 262
Query: 63 EERENPSKRSRIE----------RDIDNNLITST-------PRAGEKPNKQISRVRRKSQ 105
++ K+S +E +I+ L+ S+ P KP+ + + S+
Sbjct: 263 RQQSGSPKKSALEGSSASASQSSSEIEVPLLGSSGSSEVELPLLSSKPSSETASSGLTSK 322
Query: 106 VNGEAGSYEMTNQHVKQNGKLEDNPSSGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDS 165
+ EA ++ +G P S S T+LL + + A+K+ + S S
Sbjct: 323 TSSEASVSSSVAKNSSSSGTSLLTPKSSSSTNTSLLTSKSTSQVAASLLASKSSSQTSGS 382
Query: 166 PGQAVEAEEIVKQLDMEQVDEITTSTTTSTNGAAYSNQAVQVRPSLNN 213
+ V QL + + +TS S + + S +V+ L N
Sbjct: 383 LVSKSTSLASVSQLASKSSSQTSTSQLPSKSTSQSSESSVKFSCKLTN 430
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 35.8 bits (81), Expect = 0.085
Identities = 38/153 (24%), Positives = 65/153 (42%), Gaps = 22/153 (14%)
Query: 5 TRKASQQSNQIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLL-------SSIKKFIK 57
T K+ ++ I +R RKY V+ +L + SK +TG++ SS K ++
Sbjct: 2859 TIKSQEEDQPIIIKRKRGRPRKYP-VETTLKMKDD--SKTDTGIVTVEQSPSSSKLKVMQ 2915
Query: 58 GSTPKEERENPSKRSRIERDIDNNLITSTPRAGEKPNKQIS-----------RVRRKSQV 106
+E N +RS D + ++TS R G KP + ++ R R+KS
Sbjct: 2916 TDESNKETANLQERSISNDDGEEKIVTSVRRRGRKPKRSLTVSDDAESSEPERKRQKSVS 2975
Query: 107 NGEAGSYEMTNQHVKQNGKLEDNPSSGSPPRTT 139
+ E + ++ + ED PS + TT
Sbjct: 2976 DPVEDKKEQESDEEEEEEE-EDEPSGATTRSTT 3007
>gi|217330574 EH domain binding protein 1 isoform 3 [Homo sapiens]
Length = 1160
Score = 35.4 bits (80), Expect = 0.11
Identities = 45/161 (27%), Positives = 70/161 (43%), Gaps = 27/161 (16%)
Query: 150 NFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEIT-TSTTTSTNGAAYSN-----Q 203
NF A K+ + + +P +A E+ D + + IT T++ T + Y+N +
Sbjct: 218 NFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFK 277
Query: 204 AVQVRPSLNNGLEEAEETVN-RDIPPLTA------PVTPDSGYSSAHAEATYEEDWEVFD 256
VQ P N +E E V +D PP + PV S Y A + T EE+ + +
Sbjct: 278 EVQT-PQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDM-SKYLYADSSKTEEEELDESN 335
Query: 257 PYYFIKHVPP-----------LTEEQLNRK-PALPLKTRST 285
P+Y K PP TE ++ RK PA P+ + T
Sbjct: 336 PFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKT 376
>gi|217330572 EH domain binding protein 1 isoform 3 [Homo sapiens]
Length = 1160
Score = 35.4 bits (80), Expect = 0.11
Identities = 45/161 (27%), Positives = 70/161 (43%), Gaps = 27/161 (16%)
Query: 150 NFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEIT-TSTTTSTNGAAYSN-----Q 203
NF A K+ + + +P +A E+ D + + IT T++ T + Y+N +
Sbjct: 218 NFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFK 277
Query: 204 AVQVRPSLNNGLEEAEETVN-RDIPPLTA------PVTPDSGYSSAHAEATYEEDWEVFD 256
VQ P N +E E V +D PP + PV S Y A + T EE+ + +
Sbjct: 278 EVQT-PQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDM-SKYLYADSSKTEEEELDESN 335
Query: 257 PYYFIKHVPP-----------LTEEQLNRK-PALPLKTRST 285
P+Y K PP TE ++ RK PA P+ + T
Sbjct: 336 PFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKT 376
>gi|217330570 EH domain binding protein 1 isoform 2 [Homo sapiens]
Length = 1196
Score = 35.4 bits (80), Expect = 0.11
Identities = 45/161 (27%), Positives = 70/161 (43%), Gaps = 27/161 (16%)
Query: 150 NFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEIT-TSTTTSTNGAAYSN-----Q 203
NF A K+ + + +P +A E+ D + + IT T++ T + Y+N +
Sbjct: 218 NFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFK 277
Query: 204 AVQVRPSLNNGLEEAEETVN-RDIPPLTA------PVTPDSGYSSAHAEATYEEDWEVFD 256
VQ P N +E E V +D PP + PV S Y A + T EE+ + +
Sbjct: 278 EVQT-PQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDM-SKYLYADSSKTEEEELDESN 335
Query: 257 PYYFIKHVPP-----------LTEEQLNRK-PALPLKTRST 285
P+Y K PP TE ++ RK PA P+ + T
Sbjct: 336 PFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKT 376
>gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens]
Length = 1231
Score = 35.4 bits (80), Expect = 0.11
Identities = 45/161 (27%), Positives = 70/161 (43%), Gaps = 27/161 (16%)
Query: 150 NFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEIT-TSTTTSTNGAAYSN-----Q 203
NF A K+ + + +P +A E+ D + + IT T++ T + Y+N +
Sbjct: 253 NFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFK 312
Query: 204 AVQVRPSLNNGLEEAEETVN-RDIPPLTA------PVTPDSGYSSAHAEATYEEDWEVFD 256
VQ P N +E E V +D PP + PV S Y A + T EE+ + +
Sbjct: 313 EVQT-PQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDM-SKYLYADSSKTEEEELDESN 370
Query: 257 PYYFIKHVPP-----------LTEEQLNRK-PALPLKTRST 285
P+Y K PP TE ++ RK PA P+ + T
Sbjct: 371 PFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKT 411
>gi|114796630 homeodomain interacting protein kinase 3 isoform 2
[Homo sapiens]
Length = 1194
Score = 34.3 bits (77), Expect = 0.25
Identities = 39/201 (19%), Positives = 92/201 (45%), Gaps = 15/201 (7%)
Query: 59 STPKEERENPSKRSRIER-DIDNNLITSTPRAGEKPNKQISRVRRKSQVNGEAGSYEMTN 117
+T K+ ++ ++ + ++ +I ++ S K +++S + + N E +
Sbjct: 758 ATTKKNKQCQNRSNSLQNTNIPHSAFISPKIINGKDVEEVSCIETQDNQNSEGEARNCCE 817
Query: 118 QHVKQNGKLEDNPSSGSPPRTTLLGTIFSP---VFNFFSPANKNGTSGSDSPGQ---AVE 171
++Q+ D+ S +T ++ SP V S ++ TS S + +++
Sbjct: 818 TSIRQDS---DSSVSDKQRQTIIIADSPSPAVSVITISSDTDEEETSQRHSLRECKGSLD 874
Query: 172 AEEIVKQLDMEQVDEITT-STTTSTNGAAYSNQAVQVRPSLNNGLEEAEETVNRDIPPLT 230
E L+++++ +++ +T ST+ + S+ + RP N + + E+ + D
Sbjct: 875 CEACQSTLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRP---NSMSDEEQESSCDTVD-G 930
Query: 231 APVTPDSGYSSAHAEATYEED 251
+P + SG+ S AE+T+ ED
Sbjct: 931 SPTSDSSGHDSPFAESTFVED 951
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 34.3 bits (77), Expect = 0.25
Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 12/104 (11%)
Query: 35 PSGGEKPSKNETGLLSSIKKFIKGSTPKEERENPSKRS---RIERDIDNNLITSTPRAGE 91
P G +TG KK G + + +++ K+S + + D +S +GE
Sbjct: 647 PGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGE 706
Query: 92 KPNKQISRVRRKSQVNGEAGSYEMTNQHVKQNGKLEDNPSSGSP 135
K K+ R R+K++ + A S + G + P SGSP
Sbjct: 707 KSKKRKKRKRKKNKSSAPADS---------ERGPKPEPPGSGSP 741
>gi|40806209 WW domain containing E3 ubiquitin protein ligase 2
isoform 3 [Homo sapiens]
Length = 335
Score = 33.5 bits (75), Expect = 0.42
Identities = 44/192 (22%), Positives = 69/192 (35%), Gaps = 42/192 (21%)
Query: 33 SLPSGGEKPSKNETGLLSSIKKFIKGSTPKEERENPSK-----RSRIERDIDNNLITSTP 87
+L G + PS++ +G + P+ + PS RSR R + T TP
Sbjct: 156 ALTDGSQLPSRDSSGTAVA---------PENRHQPPSTNCFGGRSRTHRHSGASART-TP 205
Query: 88 RAGEKPNKQISRVRRKSQVNGEAGSYEMTNQHVKQNGKLEDNPSSGSPPRTTLLGTIFSP 147
GE+ SR R+ + +G +G NG + D P++ + P + + SP
Sbjct: 206 ATGEQSPGARSRHRQPVKNSGHSGL---------ANGTVNDEPTTATDPEEPSVVGVTSP 256
Query: 148 VFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTSTTTSTNGAAYSNQAVQV 207
S T+ +P E EE ST+G A Q
Sbjct: 257 PAAPLSVTPNPNTTSLPAPATPAEGEE------------------PSTSGTQQLPAAAQA 298
Query: 208 RPSLNNGLEEAE 219
+L G E+ E
Sbjct: 299 PDALPAGWEQRE 310
>gi|40806207 WW domain containing E3 ubiquitin protein ligase 2
isoform 1 [Homo sapiens]
Length = 870
Score = 33.5 bits (75), Expect = 0.42
Identities = 44/192 (22%), Positives = 69/192 (35%), Gaps = 42/192 (21%)
Query: 33 SLPSGGEKPSKNETGLLSSIKKFIKGSTPKEERENPSK-----RSRIERDIDNNLITSTP 87
+L G + PS++ +G + P+ + PS RSR R + T TP
Sbjct: 156 ALTDGSQLPSRDSSGTAVA---------PENRHQPPSTNCFGGRSRTHRHSGASART-TP 205
Query: 88 RAGEKPNKQISRVRRKSQVNGEAGSYEMTNQHVKQNGKLEDNPSSGSPPRTTLLGTIFSP 147
GE+ SR R+ + +G +G NG + D P++ + P + + SP
Sbjct: 206 ATGEQSPGARSRHRQPVKNSGHSGL---------ANGTVNDEPTTATDPEEPSVVGVTSP 256
Query: 148 VFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTSTTTSTNGAAYSNQAVQV 207
S T+ +P E EE ST+G A Q
Sbjct: 257 PAAPLSVTPNPNTTSLPAPATPAEGEE------------------PSTSGTQQLPAAAQA 298
Query: 208 RPSLNNGLEEAE 219
+L G E+ E
Sbjct: 299 PDALPAGWEQRE 310
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 33.1 bits (74), Expect = 0.55
Identities = 31/138 (22%), Positives = 53/138 (38%), Gaps = 19/138 (13%)
Query: 5 TRKASQQSNQIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTPKEE 64
TR+A +Q+++ + + + KRK+ DD+ S +KP + K G P
Sbjct: 749 TREAQKQASE---KVSNKGKRKHKNEDDNRASESKKPKTED--------KNSAGHKPSSN 797
Query: 65 RENPSKRSRIERDIDNNLITSTPRAGEKPN--------KQISRVRRKSQVNGEAGSYEMT 116
RE+ + + E+D+ + P K Q S ++ S N E
Sbjct: 798 RESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKN 857
Query: 117 NQHVKQNGKLEDNPSSGS 134
+ + K E SS S
Sbjct: 858 SSSTSKQKKTEGKTSSSS 875
>gi|193083197 ubiquitin-like domain containing CTD phosphatase 1
[Homo sapiens]
Length = 318
Score = 32.7 bits (73), Expect = 0.72
Identities = 32/139 (23%), Positives = 62/139 (44%), Gaps = 20/139 (14%)
Query: 328 LRPFFREFLERMSQMYEIILFTASKKVYAD---KLLNILDPKKQLVRHRLFREHCVCVQG 384
+RP+ EFL + Y+I++++A+ + + K L + + L + V
Sbjct: 162 MRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHT 221
Query: 385 NY-----IKDLNILGRDLSK------TIIIDNSPQAFAYQLSNGIPIESWF-----MDKN 428
+K L ++ S+ TI+ D+ + F NG+ I + DK
Sbjct: 222 PRRGLIDVKPLGVIWGKFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDK- 280
Query: 429 DNELLKLIPFLEKLVELNE 447
D ELLKL +L+++ +L++
Sbjct: 281 DKELLKLTQYLKEIAKLDD 299
>gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens]
Length = 861
Score = 32.3 bits (72), Expect = 0.94
Identities = 33/128 (25%), Positives = 50/128 (39%), Gaps = 5/128 (3%)
Query: 20 TARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGS--TPKEERENP-SKRSRIER 76
T +A S + +PS KPSK +T S +K S +P ++ P S S
Sbjct: 597 TFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSS 656
Query: 77 DIDNNLITSTPRAGEKPNKQISRVRRKSQVNG--EAGSYEMTNQHVKQNGKLEDNPSSGS 134
++L TS P+K+ + S +N A Y + H NG +
Sbjct: 657 SSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEP 716
Query: 135 PPRTTLLG 142
RT+L G
Sbjct: 717 SGRTSLPG 724
>gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens]
Length = 738
Score = 32.3 bits (72), Expect = 0.94
Identities = 33/128 (25%), Positives = 50/128 (39%), Gaps = 5/128 (3%)
Query: 20 TARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGS--TPKEERENP-SKRSRIER 76
T +A S + +PS KPSK +T S +K S +P ++ P S S
Sbjct: 473 TFKAPSAVSPIPAVIPSPSHKPSKTKTSKSSKVKDLSTRSDESPSNKKRKPQSSTSSSSS 532
Query: 77 DIDNNLITSTPRAGEKPNKQISRVRRKSQVNG--EAGSYEMTNQHVKQNGKLEDNPSSGS 134
++L TS P+K+ + S +N A Y + H NG +
Sbjct: 533 SSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEP 592
Query: 135 PPRTTLLG 142
RT+L G
Sbjct: 593 SGRTSLPG 600
>gi|114796624 homeodomain interacting protein kinase 3 isoform 1
[Homo sapiens]
Length = 1215
Score = 32.3 bits (72), Expect = 0.94
Identities = 35/167 (20%), Positives = 76/167 (45%), Gaps = 14/167 (8%)
Query: 92 KPNKQISRVRRKSQVNGEAGSYEMTNQHVKQNGKLEDNPSSGSPPRTTLLGTIFSP---V 148
K +++S + + N E + ++Q+ D+ S +T ++ SP V
Sbjct: 813 KDVEEVSCIETQDNQNSEGEARNCCETSIRQDS---DSSVSDKQRQTIIIADSPSPAVSV 869
Query: 149 FNFFSPANKNGTSGSDSPGQ---AVEAEEIVKQLDMEQVDEITT-STTTSTNGAAYSNQA 204
S ++ TS S + +++ E L+++++ +++ +T ST+ + S+ +
Sbjct: 870 ITISSDTDEEETSQRHSLRECKGSLDCEACQSTLNIDRMCSLSSPDSTLSTSSSGQSSPS 929
Query: 205 VQVRPSLNNGLEEAEETVNRDIPPLTAPVTPDSGYSSAHAEATYEED 251
RP N + + E+ + D +P + SG+ S AE+T+ ED
Sbjct: 930 PCKRP---NSMSDEEQESSCDTVD-GSPTSDSSGHDSPFAESTFVED 972
>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
Length = 2440
Score = 31.6 bits (70), Expect = 1.6
Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 5/75 (6%)
Query: 7 KASQQSNQIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTPKEERE 66
+ SQ S +Q Q+ + +R+ S + + P G ++P + T S + F G +P +
Sbjct: 49 EVSQASQLLQQQQQQQLRRRPSLLSEFHP-GSDRPQERRT----SYEPFHPGPSPVDHDS 103
Query: 67 NPSKRSRIERDIDNN 81
SKR R+E+ D++
Sbjct: 104 LESKRPRLEQVSDSH 118
>gi|4557719 DNA ligase I [Homo sapiens]
Length = 919
Score = 31.6 bits (70), Expect = 1.6
Identities = 51/229 (22%), Positives = 82/229 (35%), Gaps = 25/229 (10%)
Query: 53 KKFIKGSTPKEERENPSKRSRIERDID----NNLITSTPRAGEKPNKQISRVRRKSQVNG 108
KK K P++E N S+ + N +++ + ++P ++ +RV G
Sbjct: 12 KKEGKAKKPEKEASNSSRETEPPPKAALKEWNGVVSESDSPVKRPGRKAARVL------G 65
Query: 109 EAGSYEMTNQHVKQNGKLEDNPSSGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQ 168
G E + K + S SPPR SP N A+ + TS DS
Sbjct: 66 SEGEEEDEALSPAKGQKPALDCSQVSPPRPAT-----SPENN----ASLSDTSPMDSSPS 116
Query: 169 AVEAEEIV-KQLDMEQVDEITTSTTTSTNGAAYSNQAVQVRPSLNNGLEEAEETVNRDIP 227
+ KQL + E+ + + A + + + L EAE ++
Sbjct: 117 GIPKRRTARKQLPKRTIQEVLEEQSEDEDREAKRKKEEEEEETPKESLTEAEVATEKEGE 176
Query: 228 PLTAPVTPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKP 276
P TP ++ AE E V +P K L EE+ KP
Sbjct: 177 DGDQPTTPPKPLKTSKAETPTE---SVSEPEVATKQ--ELQEEEEQTKP 220
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,280,379
Number of Sequences: 37866
Number of extensions: 858051
Number of successful extensions: 2226
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 62
Number of HSP's that attempted gapping in prelim test: 2173
Number of HSP's gapped (non-prelim): 101
length of query: 466
length of database: 18,247,518
effective HSP length: 106
effective length of query: 360
effective length of database: 14,233,722
effective search space: 5124139920
effective search space used: 5124139920
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.