BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|186700625 Rab-like GTP-binding protein 1 isoform 2 [Homo sapiens] (520 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|186700625 Rab-like GTP-binding protein 1 isoform 2 [Homo sapi... 1084 0.0 gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi... 735 0.0 gi|157168329 formin 1 [Homo sapiens] 54 5e-07 gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo sap... 50 7e-06 gi|40548415 dishevelled associated activator of morphogenesis 2 ... 49 1e-05 gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 49 1e-05 gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 49 1e-05 gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 49 1e-05 gi|5453555 ras-related nuclear protein [Homo sapiens] 48 2e-05 gi|7662302 TBK1 binding protein 1 [Homo sapiens] 47 4e-05 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 47 4e-05 gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 46 7e-05 gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 46 7e-05 gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 46 7e-05 gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 46 7e-05 gi|34147513 RAB7, member RAS oncogene family [Homo sapiens] 46 7e-05 gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 46 9e-05 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 46 9e-05 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 46 9e-05 gi|4758996 Ras-related protein Rab-33A [Homo sapiens] 46 9e-05 gi|33356148 formin-like 1 [Homo sapiens] 46 9e-05 gi|7661922 RAB21, member RAS oncogene family [Homo sapiens] 45 1e-04 gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 45 2e-04 gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] 45 2e-04 gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] 45 2e-04 gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 45 2e-04 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 45 2e-04 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 45 2e-04 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 45 2e-04 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 45 2e-04 >gi|186700625 Rab-like GTP-binding protein 1 isoform 2 [Homo sapiens] Length = 520 Score = 1084 bits (2804), Expect = 0.0 Identities = 520/520 (100%), Positives = 520/520 (100%) Query: 1 MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALW 60 MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALW Sbjct: 1 MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALW 60 Query: 61 HRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDP 120 HRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDP Sbjct: 61 HRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDP 120 Query: 121 QEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDM 180 QEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDM Sbjct: 121 QEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDM 180 Query: 181 GEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLL 240 GEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLL Sbjct: 181 GEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLL 240 Query: 241 RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP 300 RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP Sbjct: 241 RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP 300 Query: 301 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR 360 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR Sbjct: 301 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR 360 Query: 361 PPPWGWRLRGALGRRGQWPPWGGGRACHCLGRHLPLYHRLCRCPVAAVCASELEEAGHWW 420 PPPWGWRLRGALGRRGQWPPWGGGRACHCLGRHLPLYHRLCRCPVAAVCASELEEAGHWW Sbjct: 361 PPPWGWRLRGALGRRGQWPPWGGGRACHCLGRHLPLYHRLCRCPVAAVCASELEEAGHWW 420 Query: 421 SPGWALQVLGLQAQCEPALQEGRGQLASARLGGHPGPLGAEPPVFLRDVTEAQEGPVRVC 480 SPGWALQVLGLQAQCEPALQEGRGQLASARLGGHPGPLGAEPPVFLRDVTEAQEGPVRVC Sbjct: 421 SPGWALQVLGLQAQCEPALQEGRGQLASARLGGHPGPLGAEPPVFLRDVTEAQEGPVRVC 480 Query: 481 LQRLGRGRLAVGCALPRHLLALRAHLGPQHAYGSASGREP 520 LQRLGRGRLAVGCALPRHLLALRAHLGPQHAYGSASGREP Sbjct: 481 LQRLGRGRLAVGCALPRHLLALRAHLGPQHAYGSASGREP 520 >gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapiens] Length = 729 Score = 735 bits (1897), Expect = 0.0 Identities = 360/360 (100%), Positives = 360/360 (100%) Query: 1 MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALW 60 MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALW Sbjct: 1 MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALW 60 Query: 61 HRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDP 120 HRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDP Sbjct: 61 HRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDP 120 Query: 121 QEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDM 180 QEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDM Sbjct: 121 QEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDM 180 Query: 181 GEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLL 240 GEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLL Sbjct: 181 GEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLL 240 Query: 241 RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP 300 RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP Sbjct: 241 RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP 300 Query: 301 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR 360 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR Sbjct: 301 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR 360 >gi|157168329 formin 1 [Homo sapiens] Length = 1196 Score = 53.5 bits (127), Expect = 5e-07 Identities = 51/161 (31%), Positives = 69/161 (42%), Gaps = 20/161 (12%) Query: 225 KFFNIPFLQLQRETLLRQLET-------NQLDMD----ATLEELSVQQETEDQNYGIF-L 272 K F +Q RET L+ E+ NQL ++L +LS + +D + + + Sbjct: 575 KTFRNVCVQTDRETFLKPCESESKTTRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPM 634 Query: 273 EMMEARSRGHASPLAANGQSPSP-----GSQSPVVPAGAVSTGSSSPGTPQPAPQLP--L 325 E M + + P A+ P P GS SP P VS G P P P P LP Sbjct: 635 EGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPS 694 Query: 326 NAAPPSSVPPVP-PSEALPPPACPSAPAPRRSIISRPPPWG 365 +A PP PP P P+ PP PAP ++ PPP G Sbjct: 695 SAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPG 735 >gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo sapiens] Length = 205 Score = 49.7 bits (117), Expect = 7e-06 Identities = 39/182 (21%), Positives = 83/182 (45%), Gaps = 39/182 (21%) Query: 42 YNMKIVIRGDRNTGKTALWHRLQGRPFVEEYIPT--QEIQVTSIHWSYKTTDDIVKVEVW 99 Y K+++ GD GK+ L R + E YI T + ++ +I KT +K+++W Sbjct: 10 YLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKT----IKLQIW 65 Query: 100 DVVDKGKCKKRGDGLKMENDPQEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYIL 159 D + + + + + + Y+ +G+++++D+T Q +FN + Sbjct: 66 DTAGQERFR-------------------TITSSY---YRGAHGIIVVYDVTDQESFNNVK 103 Query: 160 RELPKVPTH----VPVCVLGNYRDMGEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMK 215 + L ++ + V ++GN D+ +V+ ++F D+L P + E+S K Sbjct: 104 QWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIP-------FLETSAK 156 Query: 216 NS 217 N+ Sbjct: 157 NA 158 >gi|40548415 dishevelled associated activator of morphogenesis 2 [Homo sapiens] Length = 1067 Score = 48.9 bits (115), Expect = 1e-05 Identities = 37/115 (32%), Positives = 49/115 (42%), Gaps = 5/115 (4%) Query: 239 LLRQLETNQLDMDA-TLEELSVQQETEDQNYGIFLEMMEAR-SRGHASPLAANGQSPSPG 296 L+ +LE + + + TLE+ + + + E E R +RG + L A S G Sbjct: 458 LVSRLERKERECETKTLEKEEMMRTLNKMKDKLARESQELRQARGQVAELVAQLSELSTG 517 Query: 297 SQSPVVPAGAVSTGSSSPGT---PQPAPQLPLNAAPPSSVPPVPPSEALPPPACP 348 S P G T SSS T P P P LP PP PP+PP PP P Sbjct: 518 PVSSPPPPGGPLTLSSSMTTNDLPPPPPPLPFACCPPPPPPPLPPGGPPTPPGAP 572 >gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] Length = 1263 Score = 48.5 bits (114), Expect = 1e-05 Identities = 38/125 (30%), Positives = 58/125 (46%), Gaps = 10/125 (8%) Query: 241 RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP 300 +Q+ T + D++A + +L+ + + E+ +A+ + AA PS S++P Sbjct: 519 QQIATEKQDLEAEVSQLTGEVAK------LTKELEDAKKEMASLSAAAITVPPSVPSRAP 572 Query: 301 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAP--APRRSII 358 V PA + S + P PAP PP PP PP LP C S+P P + I Sbjct: 573 VPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPP--PLPGGVCISSPPSLPGGTAI 630 Query: 359 SRPPP 363 S PPP Sbjct: 631 SPPPP 635 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 10/82 (12%) Query: 285 PLAANGQSPSPGSQSPVVPAGA-VSTGSSSPGTPQ--PAPQLPLNAAPPSSVPPVPPSEA 341 PL+ + P P P +P G + + SS PG P P LP +A P PP+P S Sbjct: 635 PLSGDATIPPP----PPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAG 690 Query: 342 LPPPACPSAPAPRRSIISRPPP 363 +PP P P P + + PPP Sbjct: 691 IPP---PPPPLPGEAGMPPPPP 709 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 8/84 (9%) Query: 293 PSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP----PACP 348 P PGS + + P GS+ G P P P LP A P PP+P +PP P P Sbjct: 671 PLPGS-ARIPPPPPPLPGSA--GIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 727 Query: 349 SAPAPRRSI-ISRPPPWGWRLRGA 371 P P + + PPP+G+ + A Sbjct: 728 GIPPPPPGMGMPPPPPFGFGVPAA 751 Score = 38.5 bits (88), Expect = 0.015 Identities = 30/86 (34%), Positives = 37/86 (43%), Gaps = 15/86 (17%) Query: 285 PLAANGQSPSPGSQSPVVPAG-AVSTGSSSPGT---PQPAPQLPLNAAPPSSVPPVPPSE 340 PL PSP S +P G A+ PG+ P P P LP +A P PP+P Sbjct: 647 PLPEGVGIPSPSS----LPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEA 702 Query: 341 ALPPPA--CPSAPAPRRSIISRPPPW 364 +PPP P P I PPP+ Sbjct: 703 GMPPPPPPLPGGPG-----IPPPPPF 723 Score = 36.2 bits (82), Expect = 0.075 Identities = 37/118 (31%), Positives = 44/118 (37%), Gaps = 32/118 (27%) Query: 293 PSPGSQSPVVPAGA-VSTGSSSPG--------------TPQPAPQLPLNAAPPS------ 331 P P P +P G +S+ S PG T P P LP PS Sbjct: 603 PPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG 662 Query: 332 --SVPPVPP---SEALPPPACPSAPAPRRSIISRPPPWGWRLRGALGRRGQWPPWGGG 384 ++PP PP S +PP P P P + I PPP L G G PP GG Sbjct: 663 GTAIPPPPPLPGSARIPP---PPPPLPGSAGIPPPPP---PLPGEAGMPPPPPPLPGG 714 >gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] Length = 1272 Score = 48.5 bits (114), Expect = 1e-05 Identities = 38/125 (30%), Positives = 58/125 (46%), Gaps = 10/125 (8%) Query: 241 RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP 300 +Q+ T + D++A + +L+ + + E+ +A+ + AA PS S++P Sbjct: 528 QQIATEKQDLEAEVSQLTGEVAK------LTKELEDAKKEMASLSAAAITVPPSVPSRAP 581 Query: 301 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAP--APRRSII 358 V PA + S + P PAP PP PP PP LP C S+P P + I Sbjct: 582 VPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPP--PLPGGVCISSPPSLPGGTAI 639 Query: 359 SRPPP 363 S PPP Sbjct: 640 SPPPP 644 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 10/82 (12%) Query: 285 PLAANGQSPSPGSQSPVVPAGA-VSTGSSSPGTPQ--PAPQLPLNAAPPSSVPPVPPSEA 341 PL+ + P P P +P G + + SS PG P P LP +A P PP+P S Sbjct: 644 PLSGDATIPPP----PPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAG 699 Query: 342 LPPPACPSAPAPRRSIISRPPP 363 +PP P P P + + PPP Sbjct: 700 IPP---PPPPLPGEAGMPPPPP 718 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 8/84 (9%) Query: 293 PSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP----PACP 348 P PGS + + P GS+ G P P P LP A P PP+P +PP P P Sbjct: 680 PLPGS-ARIPPPPPPLPGSA--GIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 736 Query: 349 SAPAPRRSI-ISRPPPWGWRLRGA 371 P P + + PPP+G+ + A Sbjct: 737 GIPPPPPGMGMPPPPPFGFGVPAA 760 Score = 38.5 bits (88), Expect = 0.015 Identities = 30/86 (34%), Positives = 37/86 (43%), Gaps = 15/86 (17%) Query: 285 PLAANGQSPSPGSQSPVVPAG-AVSTGSSSPGT---PQPAPQLPLNAAPPSSVPPVPPSE 340 PL PSP S +P G A+ PG+ P P P LP +A P PP+P Sbjct: 656 PLPEGVGIPSPSS----LPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEA 711 Query: 341 ALPPPA--CPSAPAPRRSIISRPPPW 364 +PPP P P I PPP+ Sbjct: 712 GMPPPPPPLPGGPG-----IPPPPPF 732 Score = 36.2 bits (82), Expect = 0.075 Identities = 37/118 (31%), Positives = 44/118 (37%), Gaps = 32/118 (27%) Query: 293 PSPGSQSPVVPAGA-VSTGSSSPG--------------TPQPAPQLPLNAAPPS------ 331 P P P +P G +S+ S PG T P P LP PS Sbjct: 612 PPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG 671 Query: 332 --SVPPVPP---SEALPPPACPSAPAPRRSIISRPPPWGWRLRGALGRRGQWPPWGGG 384 ++PP PP S +PP P P P + I PPP L G G PP GG Sbjct: 672 GTAIPPPPPLPGSARIPP---PPPPLPGSAGIPPPPP---PLPGEAGMPPPPPPLPGG 723 >gi|4826998 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) [Homo sapiens] Length = 707 Score = 48.5 bits (114), Expect = 1e-05 Identities = 42/134 (31%), Positives = 51/134 (38%), Gaps = 21/134 (15%) Query: 283 ASPLAANGQSPSPG---------SQSPVVPAGAVSTGSSSPG-TPQPAPQL---PLNAAP 329 + P+ A G P+PG S P P + + S PG TP P P + P A P Sbjct: 107 SKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPP 166 Query: 330 P----SSVPPVPPSEALPPPACPSAPAPRRSIISRPPPWGWRLRGALGRRGQWPPWGGGR 385 P S VP PP PPP + P P P P G + G+ P GGG Sbjct: 167 PTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPK----GGKMPGGPKPGGGP 222 Query: 386 ACHCLGRHLPLYHR 399 G H HR Sbjct: 223 GLSTPGGHPKPPHR 236 Score = 35.4 bits (80), Expect = 0.13 Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 18/86 (20%) Query: 282 HASPLAANGQSPSP-GSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPP--SSVPPV-P 337 H P P P S PVV G P PAP + +APP SS PP P Sbjct: 90 HPQPHQQQQPPPPPQDSSKPVVAQG-----------PGPAPGV--GSAPPASSSAPPATP 136 Query: 338 PSEALPPPACPS-APAPRRSIISRPP 362 P+ PP + P P P ++ S PP Sbjct: 137 PTSGAPPGSGPGPTPTPPPAVTSAPP 162 Score = 35.0 bits (79), Expect = 0.17 Identities = 22/80 (27%), Positives = 26/80 (32%), Gaps = 8/80 (10%) Query: 290 GQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPP-------SSVPPVPPSEAL 342 G P P +P P QP PQ P PP PP PP ++ Sbjct: 48 GPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDS- 106 Query: 343 PPPACPSAPAPRRSIISRPP 362 P P P + S PP Sbjct: 107 SKPVVAQGPGPAPGVGSAPP 126 Score = 33.9 bits (76), Expect = 0.37 Identities = 19/59 (32%), Positives = 23/59 (38%), Gaps = 5/59 (8%) Query: 310 GSSSPGTPQPAPQLPLNAAPPSSV-----PPVPPSEALPPPACPSAPAPRRSIISRPPP 363 G PG Q P+ P+ PP P PP + PP P P P + PPP Sbjct: 45 GPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPP 103 >gi|5453555 ras-related nuclear protein [Homo sapiens] Length = 216 Score = 48.1 bits (113), Expect = 2e-05 Identities = 48/202 (23%), Positives = 81/202 (40%), Gaps = 43/202 (21%) Query: 41 QYNMKIVIRGDRNTGKTALWHRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWD 100 Q K+V+ GD TGKT R F ++Y+ T ++V + + T +K VWD Sbjct: 8 QVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPL--VFHTNRGPIKFNVWD 65 Query: 101 VVDKGKCKKRGDGLKMENDPQEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYI-- 158 + K DG Y ++MFD+T + T+ + Sbjct: 66 TAGQEKFGGLRDG----------------------YYIQAQCAIIMFDVTSRVTYKNVPN 103 Query: 159 -LRELPKVPTHVPVCVLGNYRDMGEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNS 217 R+L +V ++P+ + GN D+ + +V V NL +Y + S K++ Sbjct: 104 WHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNL---------QYYDISAKSN 154 Query: 218 FGLKYLHKFFNIPFLQLQRETL 239 + F PFL L R+ + Sbjct: 155 YN-------FEKPFLWLARKLI 169 >gi|7662302 TBK1 binding protein 1 [Homo sapiens] Length = 615 Score = 47.0 bits (110), Expect = 4e-05 Identities = 35/105 (33%), Positives = 43/105 (40%), Gaps = 17/105 (16%) Query: 276 EARSRGHASPLAANGQSPSPGSQSPVVPAGAVST---------GSSSPGTPQPAPQLPLN 326 +ARS G + SP+P SP PA A SP P P+PQ + Sbjct: 326 QARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRS 385 Query: 327 AAPPSSVPPVPPSEALPPPACPSAPAPRRSII--------SRPPP 363 A PS PVP + PP+C S RRS + RPPP Sbjct: 386 PASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPP 430 Score = 31.6 bits (70), Expect = 1.8 Identities = 47/195 (24%), Positives = 62/195 (31%), Gaps = 62/195 (31%) Query: 283 ASPLAANGQSPSPGSQSPVVPAGAVSTGSS--SPGTPQPAPQ------------------ 322 A+P QSP P +SPV P + S SP P P PQ Sbjct: 356 AAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRS 415 Query: 323 -LPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR---PPPWGWRLRGALGRR--- 375 +P + P PP PP P R++ R PP G GRR Sbjct: 416 PVPPSCPAPQPRPPPPP------------PPGERTLAERAYAKPPSHHVKAGFQGRRSYS 463 Query: 376 ---------GQWPPWGGGRACHCLGRHLPLYHRLCRCPVAAVCASELEEAGHWWSPGWAL 426 G PPW L P SEL G SP A Sbjct: 464 ELAEGAAYAGASPPW--------------LQAEAATLPKPRAYGSELYGPGRPLSPRRAF 509 Query: 427 QVLGLQAQCEPALQE 441 + + L+ + +P+ ++ Sbjct: 510 EGIRLRFEKQPSEED 524 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 47.0 bits (110), Expect = 4e-05 Identities = 36/115 (31%), Positives = 43/115 (37%), Gaps = 33/115 (28%) Query: 280 RGHASPLAANGQSPSPGSQSPVVP------------AGAVSTGSSSPGTPQPAPQL---- 323 RG + AA P+P P P A A +T SPG QP P+ Sbjct: 116 RGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAA 175 Query: 324 ------PLNAAPPSSVPPVPPSEALPP---------PACPSAPAPRRSIISRPPP 363 P AAPP+ PP P A PP P P PAP + +PPP Sbjct: 176 PLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQ--QQPPP 228 Score = 40.8 bits (94), Expect = 0.003 Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 10/87 (11%) Query: 287 AANGQSPSPGSQSPVVP-----AGAVSTGSSSPGTPQPAPQ-LPLNAAPPSSVPPVPPSE 340 AA Q P G+ P P A A + ++ P TP P P P+ AA P+ P + Sbjct: 96 AARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAA 155 Query: 341 ALPPPAC-PSAPAP---RRSIISRPPP 363 A PP+ P+ P P R + ++ PPP Sbjct: 156 ATAPPSPGPAQPGPRAQRAAPLAAPPP 182 Score = 38.5 bits (88), Expect = 0.015 Identities = 28/91 (30%), Positives = 34/91 (37%), Gaps = 16/91 (17%) Query: 277 ARSRGHASPLAANGQSPSPGSQSP------------VVPAGAVSTGSSSPGTPQPAPQLP 324 A +R + AA PSPG P PA A + P P+ AP Sbjct: 144 APARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPA 203 Query: 325 LNAA----PPSSVPPVPPSEALPPPACPSAP 351 + A PP PP PP + PPP P P Sbjct: 204 VAAREPPLPPPPQPPAPPQQQQPPPPQPQPP 234 Score = 36.6 bits (83), Expect = 0.057 Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 22/101 (21%) Query: 284 SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSS----------- 332 +P AA + +P S P P G + ++ P PAP P APP+ Sbjct: 148 APRAAAAAATAPPSPGPAQP-GPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAA 206 Query: 333 ----VPPVPPSEALPPPACPSAPAPRRSIISRPPPWGWRLR 369 +PP P A P P P P +PPP G +R Sbjct: 207 REPPLPPPPQPPAPPQQQQPPPPQP------QPPPEGGAVR 241 Score = 32.3 bits (72), Expect = 1.1 Identities = 22/64 (34%), Positives = 27/64 (42%), Gaps = 4/64 (6%) Query: 283 ASPLAANGQSPS--PGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSE 340 A+PLAA +P+ P P P A ++ P P P P APP P PP Sbjct: 174 AAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQP--PAPPQQQQPPPPQP 231 Query: 341 ALPP 344 PP Sbjct: 232 QPPP 235 >gi|237757312 synaptojanin 1 isoform c [Homo sapiens] Length = 1295 Score = 46.2 bits (108), Expect = 7e-05 Identities = 33/101 (32%), Positives = 46/101 (45%), Gaps = 20/101 (19%) Query: 282 HASPLAANGQSPSPGS-------QSPVVPAGAVST--------GSSSPGTPQPAPQLPLN 326 H P +++G SP S QSP + G V + S +PG P A P++ Sbjct: 1029 HLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS-AQSSPID 1087 Query: 327 AAPPSSVPPVPPSEAL----PPPACPSAPAPRRSIISRPPP 363 A P + +P P++ L PPP P AP R + RPPP Sbjct: 1088 AQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPP 1128 Score = 39.7 bits (91), Expect = 0.007 Identities = 41/150 (27%), Positives = 55/150 (36%), Gaps = 16/150 (10%) Query: 249 DMDATLEELSVQQETEDQNYGIFLEMMEA-RSRGHASPLAANGQSPS-------PGSQSP 300 D A +EEL Q + G+ + R+ SP + G PS S++P Sbjct: 1017 DYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTP 1076 Query: 301 VVPAGAVSTGSSSPGTPQPA--PQLPLNAAPPSSVPPVPPSE------ALPPPACPSAPA 352 P+ S + P TP P P PL P PV P PPP+ +PA Sbjct: 1077 GPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPA 1136 Query: 353 PRRSIISRPPPWGWRLRGALGRRGQWPPWG 382 P R P G + +GR P G Sbjct: 1137 PTRKEFGAPKSPGTTRKDNIGRSQPSPQAG 1166 Score = 35.0 bits (79), Expect = 0.17 Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 9/81 (11%) Query: 291 QSPSPGSQSPVVPAGAVSTGSSSPG-TPQPAPQLPLNAAPPSSVPPVPPSEALPPPACP- 348 QS + S + P T +S G T P P P A PP S P PP++ L P P Sbjct: 1193 QSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLP-PPAQRLQEPLVPV 1251 Query: 349 ------SAPAPRRSIISRPPP 363 S P P +PPP Sbjct: 1252 AAPMPQSGPQPNLETPPQPPP 1272 >gi|237757310 synaptojanin 1 isoform a [Homo sapiens] Length = 1612 Score = 46.2 bits (108), Expect = 7e-05 Identities = 33/101 (32%), Positives = 46/101 (45%), Gaps = 20/101 (19%) Query: 282 HASPLAANGQSPSPGS-------QSPVVPAGAVST--------GSSSPGTPQPAPQLPLN 326 H P +++G SP S QSP + G V + S +PG P A P++ Sbjct: 1068 HLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS-AQSSPID 1126 Query: 327 AAPPSSVPPVPPSEAL----PPPACPSAPAPRRSIISRPPP 363 A P + +P P++ L PPP P AP R + RPPP Sbjct: 1127 AQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPP 1167 Score = 37.7 bits (86), Expect = 0.026 Identities = 40/136 (29%), Positives = 53/136 (38%), Gaps = 19/136 (13%) Query: 249 DMDATLEELSVQQETEDQNYGIFLEMMEA-RSRGHASPLAANGQSPS-------PGSQSP 300 D A +EEL Q + G+ + R+ SP + G PS S++P Sbjct: 1056 DYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTP 1115 Query: 301 VVPAGAVSTGSSSPGTPQPA--PQLPLNAA-PPSSVPPVPPSEALPP-----PACPSAPA 352 P+ S + P TP P P PL PP P PP+ PP P+ +PA Sbjct: 1116 GPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPA 1175 Query: 353 PRRSI---ISRPPPWG 365 P R I PP G Sbjct: 1176 PTRKEFGGIGAPPSPG 1191 Score = 35.0 bits (79), Expect = 0.17 Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 9/81 (11%) Query: 291 QSPSPGSQSPVVPAGAVSTGSSSPG-TPQPAPQLPLNAAPPSSVPPVPPSEALPPPACP- 348 QS + S + P T +S G T P P P A PP S P PP++ L P P Sbjct: 1248 QSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLP-PPAQRLQEPLVPV 1306 Query: 349 ------SAPAPRRSIISRPPP 363 S P P +PPP Sbjct: 1307 AAPMPQSGPQPNLETPPQPPP 1327 Score = 30.8 bits (68), Expect = 3.1 Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 10/89 (11%) Query: 264 EDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSS---PGTPQPA 320 E++++G+ + +S+ S L N S GS + T S P P Sbjct: 1525 EEEDFGV-----KGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPP 1579 Query: 321 PQLPLNAAPPSSVPPVPPSEALPPPACPS 349 P +PL PP + PPV P L A P+ Sbjct: 1580 PPVPL--LPPGTSPPVDPFTTLASKASPT 1606 >gi|237757308 synaptojanin 1 isoform b [Homo sapiens] Length = 1350 Score = 46.2 bits (108), Expect = 7e-05 Identities = 33/101 (32%), Positives = 46/101 (45%), Gaps = 20/101 (19%) Query: 282 HASPLAANGQSPSPGS-------QSPVVPAGAVST--------GSSSPGTPQPAPQLPLN 326 H P +++G SP S QSP + G V + S +PG P A P++ Sbjct: 1068 HLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS-AQSSPID 1126 Query: 327 AAPPSSVPPVPPSEAL----PPPACPSAPAPRRSIISRPPP 363 A P + +P P++ L PPP P AP R + RPPP Sbjct: 1127 AQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPP 1167 Score = 37.7 bits (86), Expect = 0.026 Identities = 40/136 (29%), Positives = 53/136 (38%), Gaps = 19/136 (13%) Query: 249 DMDATLEELSVQQETEDQNYGIFLEMMEA-RSRGHASPLAANGQSPS-------PGSQSP 300 D A +EEL Q + G+ + R+ SP + G PS S++P Sbjct: 1056 DYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTP 1115 Query: 301 VVPAGAVSTGSSSPGTPQPA--PQLPLNAA-PPSSVPPVPPSEALPP-----PACPSAPA 352 P+ S + P TP P P PL PP P PP+ PP P+ +PA Sbjct: 1116 GPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPA 1175 Query: 353 PRRSI---ISRPPPWG 365 P R I PP G Sbjct: 1176 PTRKEFGGIGAPPSPG 1191 Score = 35.0 bits (79), Expect = 0.17 Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 9/81 (11%) Query: 291 QSPSPGSQSPVVPAGAVSTGSSSPG-TPQPAPQLPLNAAPPSSVPPVPPSEALPPPACP- 348 QS + S + P T +S G T P P P A PP S P PP++ L P P Sbjct: 1248 QSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLP-PPAQRLQEPLVPV 1306 Query: 349 ------SAPAPRRSIISRPPP 363 S P P +PPP Sbjct: 1307 AAPMPQSGPQPNLETPPQPPP 1327 >gi|237757326 synaptojanin 1 isoform d [Homo sapiens] Length = 1526 Score = 46.2 bits (108), Expect = 7e-05 Identities = 33/101 (32%), Positives = 46/101 (45%), Gaps = 20/101 (19%) Query: 282 HASPLAANGQSPSPGS-------QSPVVPAGAVST--------GSSSPGTPQPAPQLPLN 326 H P +++G SP S QSP + G V + S +PG P A P++ Sbjct: 1024 HLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS-AQSSPID 1082 Query: 327 AAPPSSVPPVPPSEAL----PPPACPSAPAPRRSIISRPPP 363 A P + +P P++ L PPP P AP R + RPPP Sbjct: 1083 AQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPP 1123 Score = 37.0 bits (84), Expect = 0.044 Identities = 36/125 (28%), Positives = 48/125 (38%), Gaps = 14/125 (11%) Query: 249 DMDATLEELSVQQETEDQNYGIFLEMMEA-RSRGHASPLAANGQSPS-------PGSQSP 300 D A +EEL Q + G+ + R+ SP + G PS S++P Sbjct: 1012 DYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTP 1071 Query: 301 VVPAGAVSTGSSSPGTPQPA--PQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSII 358 P+ S + P TP P P PL P PV P PP P P+ R Sbjct: 1072 GPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGR---- 1127 Query: 359 SRPPP 363 S+P P Sbjct: 1128 SQPSP 1132 Score = 35.0 bits (79), Expect = 0.17 Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 9/81 (11%) Query: 291 QSPSPGSQSPVVPAGAVSTGSSSPG-TPQPAPQLPLNAAPPSSVPPVPPSEALPPPACP- 348 QS + S + P T +S G T P P P A PP S P PP++ L P P Sbjct: 1162 QSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLP-PPAQRLQEPLVPV 1220 Query: 349 ------SAPAPRRSIISRPPP 363 S P P +PPP Sbjct: 1221 AAPMPQSGPQPNLETPPQPPP 1241 Score = 30.8 bits (68), Expect = 3.1 Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 10/89 (11%) Query: 264 EDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSS---PGTPQPA 320 E++++G+ + +S+ S L N S GS + T S P P Sbjct: 1439 EEEDFGV-----KGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPP 1493 Query: 321 PQLPLNAAPPSSVPPVPPSEALPPPACPS 349 P +PL PP + PPV P L A P+ Sbjct: 1494 PPVPL--LPPGTSPPVDPFTTLASKASPT 1520 >gi|34147513 RAB7, member RAS oncogene family [Homo sapiens] Length = 207 Score = 46.2 bits (108), Expect = 7e-05 Identities = 32/150 (21%), Positives = 62/150 (41%), Gaps = 32/150 (21%) Query: 44 MKIVIRGDRNTGKTALWHRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVD 103 +K++I GD GKT+L ++ + F +Y T I + D +V +++WD Sbjct: 9 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKAT--IGADFLTKEVMVDDRLVTMQIWDTAG 66 Query: 104 KGKCKKRGDGLKMENDPQEAESEMALDAEFLDVYKNCNGVVMMFDIT--------KQWTF 155 + + + G + Y+ + V++FD+T W Sbjct: 67 QERFQSLG----------------------VAFYRGADCCVLVFDVTAPNTFKTLDSWRD 104 Query: 156 NYILRELPKVPTHVPVCVLGNYRDMGEHRV 185 ++++ P+ P + P VLGN D+ +V Sbjct: 105 EFLIQASPRDPENFPFVVLGNKIDLENRQV 134 >gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sapiens] Length = 505 Score = 45.8 bits (107), Expect = 9e-05 Identities = 31/89 (34%), Positives = 37/89 (41%), Gaps = 2/89 (2%) Query: 277 ARSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPV 336 AR RG P + + +P P P+ AV + P P P LP +A PS PP Sbjct: 304 ARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSA--PSGPPPP 361 Query: 337 PPSEALPPPACPSAPAPRRSIISRPPPWG 365 PPS P P P P PPP G Sbjct: 362 PPSVLGVGPVAPPPPPPPPPPPGPPPPPG 390 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/128 (29%), Positives = 46/128 (35%), Gaps = 11/128 (8%) Query: 246 NQLDMDATLEELSVQQETEDQNYGIF-----LEMMEARSRGHASPLAANGQSPSPGSQSP 300 N DM E +ET Y +E ++ R A P + P P Sbjct: 234 NLFDMCGISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPP 293 Query: 301 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPA-----CPSAPAPRR 355 +G + G P P P AAPP PP PS A+PPP P PA Sbjct: 294 PHNSGPPPPPARGRGAPPPPPSRAPTAAPPPP-PPSRPSVAVPPPPPNRMYPPPPPALPS 352 Query: 356 SIISRPPP 363 S S PPP Sbjct: 353 SAPSGPPP 360 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 45.8 bits (107), Expect = 9e-05 Identities = 28/77 (36%), Positives = 35/77 (45%), Gaps = 9/77 (11%) Query: 293 PSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSE------ALPPPA 346 PSP Q+P P + SP P+ P AAPP VPP PP+ A PPP Sbjct: 444 PSPPVQAPFSPPASPPV---SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500 Query: 347 CPSAPAPRRSIISRPPP 363 P A +++PPP Sbjct: 501 APPPLAAPPLQLAKPPP 517 Score = 40.4 bits (93), Expect = 0.004 Identities = 34/109 (31%), Positives = 47/109 (43%), Gaps = 23/109 (21%) Query: 272 LEMMEARSRGHASPLAANGQSPSPGS---------QSPVVPAGAVSTGSSSPGTPQPAPQ 322 L ++A ASP + +PSP + Q+P P S +P +P +P Sbjct: 402 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP--SPPVQAPFSPPASPP 459 Query: 323 LPLNAAPPSSVPP--------VPPSEALPPPACPSAPAPRRSIISRPPP 363 + +A PPS PP VPPS PP PSA P ++ PPP Sbjct: 460 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA----PPP 504 Score = 38.5 bits (88), Expect = 0.015 Identities = 29/83 (34%), Positives = 35/83 (42%), Gaps = 4/83 (4%) Query: 284 SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPV--PPSE- 340 SP A+ SPS S P+ A P P P P PP + PP+ PP + Sbjct: 453 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512 Query: 341 ALPPPACPSAPA-PRRSIISRPP 362 A PPP P A A P + PP Sbjct: 513 AKPPPQAPPALATPPLQALPSPP 535 Score = 36.6 bits (83), Expect = 0.057 Identities = 36/98 (36%), Positives = 46/98 (46%), Gaps = 21/98 (21%) Query: 283 ASPLAANGQSPSPGSQS-PVVPAGAVSTGSSSPGTPQPAPQLPL----NAAPPS-----S 332 +SPLA S + SQ+ P +PA T SS T Q A LPL +APPS S Sbjct: 301 SSPLATPSPSAALQSQAPPTLPA----TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS 356 Query: 333 VPPVPPSEALPPPACPS-------APAPRRSIISRPPP 363 P PPS+A P+ P+P S ++ PPP Sbjct: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 394 Score = 36.2 bits (82), Expect = 0.075 Identities = 34/106 (32%), Positives = 42/106 (39%), Gaps = 27/106 (25%) Query: 285 PLAANGQSPSPGSQS-PVVPAGAVSTGSSSPGTPQ--------PAPQLPLNAAPPSSVPP 335 PLA S P Q+ P PA S ++S G+P P+P L A PP PP Sbjct: 339 PLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP 398 Query: 336 ---VPPSEALPPP---------ACPSAPAPRRSIIS------RPPP 363 +PP +A P P A PS AP + PPP Sbjct: 399 ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 444 Score = 35.8 bits (81), Expect = 0.097 Identities = 28/76 (36%), Positives = 35/76 (46%), Gaps = 7/76 (9%) Query: 285 PLAANGQSPS--PGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPP-SEA 341 PL A P+ PG Q+P P+ ++ + PQ P L AAP VPP PP S Sbjct: 527 PLQALPSPPASFPG-QAPFSPSASLPMSPLATPPPQAPPVL---AAPLLQVPPSPPASPT 582 Query: 342 LPPPACPSAPAPRRSI 357 L P P P P S+ Sbjct: 583 LQAPRRPPTPGPDTSV 598 Score = 34.3 bits (77), Expect = 0.28 Identities = 33/91 (36%), Positives = 39/91 (42%), Gaps = 26/91 (28%) Query: 285 PLAANG-QSPSPGSQSPVVPAGAVSTGSSSPGTP---------QPAPQLPLN--AAPPSS 332 PLAA Q P Q+P PA A + P P P+ LP++ A PP Sbjct: 504 PLAAPPLQLAKPPPQAP--PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 561 Query: 333 VPP--------VPPSEALPPPACPSAPAPRR 355 PP VPPS PPA P+ APRR Sbjct: 562 APPVLAAPLLQVPPS----PPASPTLQAPRR 588 Score = 32.3 bits (72), Expect = 1.1 Identities = 30/95 (31%), Positives = 37/95 (38%), Gaps = 16/95 (16%) Query: 284 SPLAANGQSPS---PGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNA--APPSSVP---P 335 SP A+ SPS P P + A + P P PL A +PP+S P P Sbjct: 484 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543 Query: 336 VPPSEALP--------PPACPSAPAPRRSIISRPP 362 PS +LP P A P AP + PP Sbjct: 544 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 578 Score = 30.8 bits (68), Expect = 3.1 Identities = 27/96 (28%), Positives = 32/96 (33%), Gaps = 7/96 (7%) Query: 288 ANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPAC 347 A G P P +G G SS T P ++ P PP +A Sbjct: 608 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 667 Query: 348 PSAPAPRRSIISRPPPWGWRLRGALGRRGQWPPWGG 383 P+A SR P RGA G WPP G Sbjct: 668 PAA-------WSRGPAPPLAFRGAPGAPLPWPPATG 696 Score = 30.4 bits (67), Expect = 4.1 Identities = 22/77 (28%), Positives = 29/77 (37%), Gaps = 3/77 (3%) Query: 283 ASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEAL 342 A A G++ +S + T +PGTP PA AA P P A Sbjct: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 197 Query: 343 PPPACPSAPAPRRSIIS 359 P P PR+S+ S Sbjct: 198 PR---PPTEGPRKSVSS 211 Score = 29.6 bits (65), Expect = 7.0 Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 13/89 (14%) Query: 287 AANGQSPSPGSQSPVVPAGAVSTGSSSP----------GTPQPAPQLPLNAAPPSSVPPV 336 +A + P+ G + V A ST SP G +PA + ++A P S P Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254 Query: 337 --PPSEALP-PPACPSAPAPRRSIISRPP 362 P + P PA PS P P+ RPP Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPP 283 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 45.8 bits (107), Expect = 9e-05 Identities = 28/77 (36%), Positives = 35/77 (45%), Gaps = 9/77 (11%) Query: 293 PSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSE------ALPPPA 346 PSP Q+P P + SP P+ P AAPP VPP PP+ A PPP Sbjct: 405 PSPPVQAPFSPPASPPV---SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461 Query: 347 CPSAPAPRRSIISRPPP 363 P A +++PPP Sbjct: 462 APPPLAAPPLQLAKPPP 478 Score = 40.4 bits (93), Expect = 0.004 Identities = 34/109 (31%), Positives = 47/109 (43%), Gaps = 23/109 (21%) Query: 272 LEMMEARSRGHASPLAANGQSPSPGS---------QSPVVPAGAVSTGSSSPGTPQPAPQ 322 L ++A ASP + +PSP + Q+P P S +P +P +P Sbjct: 363 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP--SPPVQAPFSPPASPP 420 Query: 323 LPLNAAPPSSVPP--------VPPSEALPPPACPSAPAPRRSIISRPPP 363 + +A PPS PP VPPS PP PSA P ++ PPP Sbjct: 421 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA----PPP 465 Score = 38.5 bits (88), Expect = 0.015 Identities = 29/83 (34%), Positives = 35/83 (42%), Gaps = 4/83 (4%) Query: 284 SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPV--PPSE- 340 SP A+ SPS S P+ A P P P P PP + PP+ PP + Sbjct: 414 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 473 Query: 341 ALPPPACPSAPA-PRRSIISRPP 362 A PPP P A A P + PP Sbjct: 474 AKPPPQAPPALATPPLQALPSPP 496 Score = 35.8 bits (81), Expect = 0.097 Identities = 28/76 (36%), Positives = 35/76 (46%), Gaps = 7/76 (9%) Query: 285 PLAANGQSPS--PGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPP-SEA 341 PL A P+ PG Q+P P+ ++ + PQ P L AAP VPP PP S Sbjct: 488 PLQALPSPPASFPG-QAPFSPSASLPMSPLATPPPQAPPVL---AAPLLQVPPSPPASPT 543 Query: 342 LPPPACPSAPAPRRSI 357 L P P P P S+ Sbjct: 544 LQAPRRPPTPGPDTSV 559 Score = 35.4 bits (80), Expect = 0.13 Identities = 34/107 (31%), Positives = 42/107 (39%), Gaps = 27/107 (25%) Query: 284 SPLAANGQSPSPGSQS-PVVPAGAVSTGSSSPGTPQ--------PAPQLPLNAAPPSSVP 334 SP A S P Q+ P PA S ++S G+P P+P L A PP P Sbjct: 299 SPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 358 Query: 335 P---VPPSEALPPP---------ACPSAPAPRRSIIS------RPPP 363 P +PP +A P P A PS AP + PPP Sbjct: 359 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 405 Score = 34.3 bits (77), Expect = 0.28 Identities = 33/91 (36%), Positives = 39/91 (42%), Gaps = 26/91 (28%) Query: 285 PLAANG-QSPSPGSQSPVVPAGAVSTGSSSPGTP---------QPAPQLPLN--AAPPSS 332 PLAA Q P Q+P PA A + P P P+ LP++ A PP Sbjct: 465 PLAAPPLQLAKPPPQAP--PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 522 Query: 333 VPP--------VPPSEALPPPACPSAPAPRR 355 PP VPPS PPA P+ APRR Sbjct: 523 APPVLAAPLLQVPPS----PPASPTLQAPRR 549 Score = 32.3 bits (72), Expect = 1.1 Identities = 30/95 (31%), Positives = 37/95 (38%), Gaps = 16/95 (16%) Query: 284 SPLAANGQSPS---PGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNA--APPSSVP---P 335 SP A+ SPS P P + A + P P PL A +PP+S P P Sbjct: 445 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 504 Query: 336 VPPSEALP--------PPACPSAPAPRRSIISRPP 362 PS +LP P A P AP + PP Sbjct: 505 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 539 Score = 30.8 bits (68), Expect = 3.1 Identities = 27/96 (28%), Positives = 32/96 (33%), Gaps = 7/96 (7%) Query: 288 ANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPAC 347 A G P P +G G SS T P ++ P PP +A Sbjct: 569 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 628 Query: 348 PSAPAPRRSIISRPPPWGWRLRGALGRRGQWPPWGG 383 P+A SR P RGA G WPP G Sbjct: 629 PAA-------WSRGPAPPLAFRGAPGAPLPWPPATG 657 Score = 30.4 bits (67), Expect = 4.1 Identities = 22/77 (28%), Positives = 29/77 (37%), Gaps = 3/77 (3%) Query: 283 ASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEAL 342 A A G++ +S + T +PGTP PA AA P P A Sbjct: 129 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 188 Query: 343 PPPACPSAPAPRRSIIS 359 P P PR+S+ S Sbjct: 189 PR---PPTEGPRKSVSS 202 Score = 30.0 bits (66), Expect = 5.3 Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 3/70 (4%) Query: 287 AANGQSPSPGSQSPVVPAG--AVSTGSSSPGTPQPAPQL-PLNAAPPSSVPPVPPSEALP 343 +A G +P S P G A+ +P AP L PL+++P ++ P P Sbjct: 249 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA 308 Query: 344 PPACPSAPAP 353 PP+ + P+P Sbjct: 309 PPSLQTLPSP 318 Score = 30.0 bits (66), Expect = 5.3 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 17/102 (16%) Query: 278 RSRGHASPLAANG-QSPSPGSQSPVVPAGAVSTG--SSSPGTPQPAPQLPLNAAPPSSVP 334 R+ H S G Q+ P +P A + G SSSP P+P P + + P S+ Sbjct: 255 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP-LATPSPSAPPSPSAPPSLQ 313 Query: 335 PVPPSEALPPPACPSA-------------PAPRRSIISRPPP 363 +P A PP ++ P+P S ++ PPP Sbjct: 314 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 355 >gi|4758996 Ras-related protein Rab-33A [Homo sapiens] Length = 237 Score = 45.8 bits (107), Expect = 9e-05 Identities = 44/169 (26%), Positives = 72/169 (42%), Gaps = 37/169 (21%) Query: 23 AGLQSMNQALQRRFAKGVQYNM-KIVIRGDRNTGKTALWHRLQGRPFVEEYIPTQEIQVT 81 AGL S+ L + VQ + KI++ GD N GKT L R G F P + Sbjct: 17 AGLASLE--LDSSLDQYVQIRIFKIIVIGDSNVGKTCLTFRFCGGTF-----PDKTEATI 69 Query: 82 SIHWSYKTTD---DIVKVEVWDVVDKGKCKKRGDGLKMENDPQEAESEMALDAEFLDVYK 138 + + KT + + +KV+VWD + + +K + Y+ Sbjct: 70 GVDFREKTVEIEGEKIKVQVWDTAGQERFRK---------------------SMVEHYYR 108 Query: 139 NCNGVVMMFDITKQWTFNYILRELPK-----VPTHVPVCVLGNYRDMGE 182 N + VV ++D+TK +F + + + VP VP ++GN D+ E Sbjct: 109 NVHAVVFVYDVTKMTSFTNLKMWIQECNGHAVPPLVPKVLVGNKCDLRE 157 >gi|33356148 formin-like 1 [Homo sapiens] Length = 1100 Score = 45.8 bits (107), Expect = 9e-05 Identities = 37/109 (33%), Positives = 42/109 (38%), Gaps = 24/109 (22%) Query: 281 GHASPLAANGQSPSPGSQSPV------------VPAGAVSTGSSSPGTPQP--APQLPLN 326 G SP A P+PG+ P P A PG+P+P AP LP + Sbjct: 524 GSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGD 583 Query: 327 AAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRPPPWGWRLRGALGRR 375 PP PP PP P P P P PPP G ALGRR Sbjct: 584 LPPPPPPPPPPPGTDGPVPPPPPPPP--------PPPGG--PPDALGRR 622 Score = 44.7 bits (104), Expect = 2e-04 Identities = 29/81 (35%), Positives = 37/81 (45%), Gaps = 7/81 (8%) Query: 288 ANGQSPSPG----SQSPVVPAGAVSTGSSSPGTPQPAPQLPL-NAAPPSSVPPVPPSEAL 342 + G +P+PG S SP + A ++P P P P LP APPS+ P PP Sbjct: 512 SGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGS 571 Query: 343 PPPACPSAPAPRRSIISRPPP 363 P P P AP + PPP Sbjct: 572 PEP--PPAPPLPGDLPPPPPP 590 Score = 36.6 bits (83), Expect = 0.057 Identities = 29/72 (40%), Positives = 34/72 (47%), Gaps = 8/72 (11%) Query: 300 PVVPAGAVSTGSSSPGTP--QPAPQLPLNA--APPSSVPPVPPSEALPPP--ACPSAP-- 351 PV A + +PG P P+P L A AP ++ PP PP LP P A PSAP Sbjct: 505 PVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQ 564 Query: 352 APRRSIISRPPP 363 AP PPP Sbjct: 565 APPLPGSPEPPP 576 Score = 29.3 bits (64), Expect = 9.1 Identities = 41/187 (21%), Positives = 61/187 (32%), Gaps = 46/187 (24%) Query: 222 YLHKFFNIPFLQLQRET---LLRQLETNQLDM--------DATLEELSVQQETEDQNYGI 270 YL F++ L ET +L +E Q + DA E ++ E E Q Sbjct: 377 YLDNIFDVGALLEDTETKNAVLEHMEELQEQVALLTERLRDAENESMAKIAELEKQLSQA 436 Query: 271 FLEMMEARSR-GHASPLAANGQSPSPGSQSPVVPAGAVSTGSS--------------SPG 315 E+ R R ++ + A+ + P P P P + PG Sbjct: 437 RKELETLRERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPG 496 Query: 316 TPQPAPQLPLNAAPPS--------------------SVPPVPPSEALPPPACPSAPAPRR 355 LP+ A PS + P P + PPP P P+P+ Sbjct: 497 DAVSIEILPVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQE 556 Query: 356 SIISRPP 362 + S PP Sbjct: 557 APPSAPP 563 >gi|7661922 RAB21, member RAS oncogene family [Homo sapiens] Length = 225 Score = 45.4 bits (106), Expect = 1e-04 Identities = 47/217 (21%), Positives = 96/217 (44%), Gaps = 46/217 (21%) Query: 37 AKGVQYNMKIVIRGDRNTGKTALWHRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKV 96 A G Y+ K+V+ G+ GKT+L R F +++I T +Q + + V + Sbjct: 13 AAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITT--LQASFLTKKLNIGGKRVNL 70 Query: 97 EVWDVVDKGKCKKRGDGLKMENDPQEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFN 156 +WD + + G Y++ NG ++++DIT + +F Sbjct: 71 AIWDTAGQERFHALGP----------------------IYYRDSNGAILVYDITDEDSFQ 108 Query: 157 YI---LRELPK-VPTHVPVCVLGNYRDMGEHRVILPDDVRDFIDNLDRPPGSSYFRYAES 212 + ++EL K + + +C++GN D+ + R + + + +++ G+ ++ + Sbjct: 109 KVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESV----GAKHY---HT 161 Query: 213 SMKNSFGLKYLHKFFNIPFLQLQRETLLRQLETNQLD 249 S K + G++ L FL L + R +ET Q+D Sbjct: 162 SAKQNKGIEEL-------FLDLCK----RMIETAQVD 187 >gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] Length = 1682 Score = 45.1 bits (105), Expect = 2e-04 Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 7/76 (9%) Query: 288 ANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPAC 347 A+ QSP P +P A AV+ +++ T PP ++PP PP PPP+ Sbjct: 730 ASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQ 789 Query: 348 PSAPAPRRSIISRPPP 363 P P P PPP Sbjct: 790 PQPPPP-------PPP 798 Score = 37.0 bits (84), Expect = 0.044 Identities = 33/104 (31%), Positives = 41/104 (39%), Gaps = 22/104 (21%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSS------PGTPQPAPQLPLNAAPPSSVPPVPP 338 P A +G P + + P G G +S PG P P P LP PP PP PP Sbjct: 211 PAALSG----PSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLP---PPP---PPPPP 260 Query: 339 SEALPPPACPSAPAPRRSIISRPPPWGWRLRGALG--RRGQWPP 380 PPP P +++P W A G R+G PP Sbjct: 261 ----PPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP 300 Score = 33.1 bits (74), Expect = 0.63 Identities = 31/95 (32%), Positives = 38/95 (40%), Gaps = 17/95 (17%) Query: 279 SRGHASPLAANGQSPSPG---SQSPVVPAGAVS----TGSSSPGTPQPAPQLPLNAAPPS 331 S +S G P+PG + PA VS G S+ + +P P A P Sbjct: 401 SSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPA-ATPHL 459 Query: 332 SVPPVPPSEALPPPACPSAPAPRRSIISRPPPWGW 366 S+PP P S PPP CP P PPP W Sbjct: 460 SLPPGPSSP--PPPPCPRLLRP-------PPPPAW 485 Score = 30.8 bits (68), Expect = 3.1 Identities = 18/54 (33%), Positives = 21/54 (38%), Gaps = 1/54 (1%) Query: 283 ASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGT-PQPAPQLPLNAAPPSSVPP 335 A+P A PS S S +G G P P P P PP S+PP Sbjct: 853 AAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPP 906 Score = 30.4 bits (67), Expect = 4.1 Identities = 16/52 (30%), Positives = 24/52 (46%), Gaps = 2/52 (3%) Query: 309 TGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR 360 TG++ P P P + PPS +PP+ A P+ +P P S S+ Sbjct: 821 TGAAVSTRPGPLPTTQYSPGPPSGATALPPTSA--APSAQGSPQPSASSSSQ 870 Score = 30.4 bits (67), Expect = 4.1 Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 12/70 (17%) Query: 310 GSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALP----------PPACPSAPAPRRSIIS 359 G +S P AP P +AP S P PPS ++P PP A + +S Sbjct: 1039 GGASKAKPPTAPAPP--SAPAPSAQPTPPSASVPGKKAREEAPGPPGVSRADMLKLRSLS 1096 Query: 360 RPPPWGWRLR 369 PP ++R Sbjct: 1097 EGPPKELKIR 1106 Score = 30.0 bits (66), Expect = 5.3 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 11/76 (14%) Query: 275 MEARSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVP 334 +E G P A + + P G+ + P ++ G SSP P P P+L + Sbjct: 430 LEVSHHGRLGPSAHSSRKPFLGAPA-ATPHLSLPPGPSSP-PPPPCPRL---------LR 478 Query: 335 PVPPSEALPPPACPSA 350 P PP L PAC +A Sbjct: 479 PPPPPAWLKGPACRAA 494 >gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] Length = 1096 Score = 45.1 bits (105), Expect = 2e-04 Identities = 39/130 (30%), Positives = 54/130 (41%), Gaps = 17/130 (13%) Query: 255 EELSVQQET--EDQNYGIFLEMMEA---RSRGHASPLAANGQSPSPGSQSPVVPAGAVST 309 EE + +QE E Q ++ +EA + R A L+++ P P + P+ G Sbjct: 506 EEFTARQEAQAELQKRDEKIKELEAEIQQLRTQAQVLSSSSGIPGPPAAPPLPGVG---- 561 Query: 310 GSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACP----SAPAPRRSIISRPPPWG 365 P P PAP LP A P PP+P +PPP P P P + PPP G Sbjct: 562 ----PPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLLFGGPPPPPPLGGVPPPPG 617 Query: 366 WRLRGALGRR 375 L G + Sbjct: 618 ISLNLPYGMK 627 >gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] Length = 1101 Score = 45.1 bits (105), Expect = 2e-04 Identities = 39/130 (30%), Positives = 54/130 (41%), Gaps = 17/130 (13%) Query: 255 EELSVQQET--EDQNYGIFLEMMEA---RSRGHASPLAANGQSPSPGSQSPVVPAGAVST 309 EE + +QE E Q ++ +EA + R A L+++ P P + P+ G Sbjct: 506 EEFTARQEAQAELQKRDEKIKELEAEIQQLRTQAQVLSSSSGIPGPPAAPPLPGVG---- 561 Query: 310 GSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACP----SAPAPRRSIISRPPPWG 365 P P PAP LP A P PP+P +PPP P P P + PPP G Sbjct: 562 ----PPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLLFGGPPPPPPLGGVPPPPG 617 Query: 366 WRLRGALGRR 375 L G + Sbjct: 618 ISLNLPYGMK 627 >gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] Length = 2817 Score = 45.1 bits (105), Expect = 2e-04 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 6/90 (6%) Query: 274 MMEARSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSV 333 + +A+S PLA+ +P P S S VPA ST + P T P P P S++ Sbjct: 1737 IQQAQSSASVPPLAS---APLPPSTSASVPA---STSAPLPATLTPVPASTSAPVPASTL 1790 Query: 334 PPVPPSEALPPPACPSAPAPRRSIISRPPP 363 PV S + P PA P AP + +S P Sbjct: 1791 APVLASTSAPVPASPLAPVSASASVSASVP 1820 Score = 41.2 bits (95), Expect = 0.002 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 8/86 (9%) Query: 284 SPLAANGQSPSPGS--QSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVP---P 338 +P+ A+ +P+ + S +P A + S+S TP PA P AAP + P +P P Sbjct: 1841 TPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSP--AAPVITAPTIPASAP 1898 Query: 339 SEALP-PPACPSAPAPRRSIISRPPP 363 + ++P PA SAPAP + +S P P Sbjct: 1899 TASVPLAPASASAPAPAPTPVSAPNP 1924 Score = 36.6 bits (83), Expect = 0.057 Identities = 27/80 (33%), Positives = 40/80 (50%), Gaps = 6/80 (7%) Query: 283 ASPLAA-NGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEA 341 AS LA+ + +P+P + SP P V T + P + P +PL A S+ P P + Sbjct: 1865 ASALASTSAPTPAPAASSPAAP---VITAPTIPASA-PTASVPLAPASASAPAPAPTPVS 1920 Query: 342 LPPPACPSAPAPRRSIISRP 361 P PA P APA ++ +P Sbjct: 1921 APNPA-PPAPAQTQAQTHKP 1939 Score = 35.0 bits (79), Expect = 0.17 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 5/85 (5%) Query: 283 ASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPA-PQLPLNAAP--PSSVPPVPPS 339 ++PL A +P P S S VPA ++ +S P PA P P++A+ +SVP + Sbjct: 1767 SAPLPAT-LTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSA 1825 Query: 340 EALPPPACP-SAPAPRRSIISRPPP 363 A+ + P SAPAP + S P Sbjct: 1826 AAITSSSAPASAPAPTPILASVSTP 1850 Score = 33.5 bits (75), Expect = 0.48 Identities = 26/124 (20%), Positives = 45/124 (36%), Gaps = 10/124 (8%) Query: 232 LQLQRETLLRQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQ 291 L+ +RE L ++E + +++ +E+ + + +F RS A+P+ + Sbjct: 589 LEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETE 648 Query: 292 SPSPGSQSPVVPAGAVSTGSSS----------PGTPQPAPQLPLNAAPPSSVPPVPPSEA 341 S P V +G S Q Q P +VP P S Sbjct: 649 PESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSST 708 Query: 342 LPPP 345 +PPP Sbjct: 709 VPPP 712 Score = 30.4 bits (67), Expect = 4.1 Identities = 18/63 (28%), Positives = 32/63 (50%), Gaps = 2/63 (3%) Query: 284 SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALP 343 +P+ A+ +P P S P+ P A ++ S+S A + ++AP S+ P P ++ Sbjct: 1791 APVLASTSAPVPAS--PLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVS 1848 Query: 344 PPA 346 PA Sbjct: 1849 TPA 1851 Score = 30.0 bits (66), Expect = 5.3 Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 7/77 (9%) Query: 288 ANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVP-------PSE 340 AN + S S+ P A +TG + P L PPS+ VP P+ Sbjct: 1714 ANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPAT 1773 Query: 341 ALPPPACPSAPAPRRSI 357 P PA SAP P ++ Sbjct: 1774 LTPVPASTSAPVPASTL 1790 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 44.7 bits (104), Expect = 2e-04 Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 5/77 (6%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP 344 P + P+P +P G ST S +PAP P AP + P P + P Sbjct: 655 PAPTTPKKPAPKELAPTTTKGPTSTTSD-----KPAPTTPKETAPTTPKEPAPTTPKKPA 709 Query: 345 PACPSAPAPRRSIISRP 361 P P P P S +S P Sbjct: 710 PTTPETPPPTTSEVSTP 726 Score = 40.8 bits (94), Expect = 0.003 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 5/70 (7%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVPPSEALP 343 P + P+P + P +T S+P TP +PAP P AP + P P + P Sbjct: 270 PAPTTPKEPAPTTTKEPAP----TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 325 Query: 344 PPACPSAPAP 353 P P PAP Sbjct: 326 TPTTPKEPAP 335 Score = 38.9 bits (89), Expect = 0.012 Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 2/62 (3%) Query: 294 SPGSQSPVVPAGAVSTGSSSPG--TPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAP 351 +P +P P T P T +PAP P AP + P P + P P P P Sbjct: 313 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 372 Query: 352 AP 353 AP Sbjct: 373 AP 374 Score = 38.1 bits (87), Expect = 0.020 Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 12/90 (13%) Query: 284 SPLAANGQSPSPGSQSPVVPAG-AVSTGSSSPGTP---------QPAPQLPLNAAPPSSV 333 SP +P+ +P A +T S+P TP +PAP P AP + Sbjct: 381 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 440 Query: 334 PPVPPSEALPPPACPSAPAPRRSIISRPPP 363 P P + P P P PAP + +P P Sbjct: 441 KPAPTTPKEPAPTTPKEPAP--TTTKKPAP 468 Score = 38.1 bits (87), Expect = 0.020 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%) Query: 291 QSPSPGSQSPVVPAGAVSTGSSSPGTPQ-PAPQLPLNAAPPSSVPPVPPSEALPPPACPS 349 + P+P + + P + +P TP+ PAP P AAP + P P + P P P Sbjct: 504 EKPAPTTPEELAPT---TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 560 Query: 350 APAP 353 PAP Sbjct: 561 EPAP 564 Score = 36.2 bits (82), Expect = 0.075 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 3/69 (4%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP 344 P + P+P ++ P P ++P +PAP P AP + P P + P Sbjct: 325 PTPTTPKEPAPTTKEPA-PTTPKEPAPTAP--KKPAPTTPKEPAPTTPKEPAPTTTKEPS 381 Query: 345 PACPSAPAP 353 P P PAP Sbjct: 382 PTTPKEPAP 390 Score = 35.0 bits (79), Expect = 0.17 Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 4/73 (5%) Query: 284 SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPG--TP-QPAPQLPLNAAPPSSVPPVPPSE 340 +P +P+ +P P T P TP +PAP P P + P P ++ Sbjct: 279 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 338 Query: 341 ALPPPACPSAPAP 353 P P P PAP Sbjct: 339 E-PAPTTPKEPAP 350 Score = 35.0 bits (79), Expect = 0.17 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 6/76 (7%) Query: 283 ASPLAANGQSPS----PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVP 337 ++P SP+ P +P PA + +P TP +PAP P AP ++ P P Sbjct: 410 SAPTTPKEPSPTTTKEPAPTTPKEPA-PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 468 Query: 338 PSEALPPPACPSAPAP 353 + P P P AP Sbjct: 469 TTPKEPAPTTPKETAP 484 Score = 34.3 bits (77), Expect = 0.28 Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 2/59 (3%) Query: 295 PGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAP 353 P S +P P +T S+P TP+ +AP + P P + P P P PAP Sbjct: 224 PASTTPKEPTP--TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 280 Score = 34.3 bits (77), Expect = 0.28 Identities = 19/76 (25%), Positives = 28/76 (36%), Gaps = 6/76 (7%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP------QPAPQLPLNAAPPSSVPPVPP 338 P + P+P + P ++P P +PAP P AP + P Sbjct: 522 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT 581 Query: 339 SEALPPPACPSAPAPR 354 + P P P PAP+ Sbjct: 582 TLKEPAPTTPKKPAPK 597 Score = 33.9 bits (76), Expect = 0.37 Identities = 22/81 (27%), Positives = 31/81 (38%), Gaps = 11/81 (13%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTG----------SSSPGTP-QPAPQLPLNAAPPSSV 333 P + P+P +P ST ++P TP +PAP P AP + Sbjct: 586 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 645 Query: 334 PPVPPSEALPPPACPSAPAPR 354 P + P P P PAP+ Sbjct: 646 GTAPTTLKEPAPTTPKKPAPK 666 Score = 33.5 bits (75), Expect = 0.48 Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 23/90 (25%) Query: 285 PLAANGQSPSPGS--QSPVVPAG-AVSTGSSSPGTP---------QPAPQLPLNAAPPSS 332 P + + P+P + +P P A +T S+P TP +PAP P AP ++ Sbjct: 224 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 283 Query: 333 VPPVP---------PSEALPPPACPSAPAP 353 P P P E P P P PAP Sbjct: 284 KEPAPTTTKSAPTTPKE--PAPTTPKKPAP 311 Score = 32.7 bits (73), Expect = 0.82 Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 6/62 (9%) Query: 295 PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAP--PSSVPPVPPSEALPPPACPSAP 351 P +P PA +T +P TP +PAP P AP P + P P + P P P Sbjct: 450 PAPTTPKEPA-PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL--APTTPEKP 506 Query: 352 AP 353 AP Sbjct: 507 AP 508 Score = 32.0 bits (71), Expect = 1.4 Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 7/65 (10%) Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQ-PAPQLPLNAAP--PSSVPPVPPSEALPPPACP 348 +P +P P T +P TP+ PAP P AP P P P E P P P Sbjct: 478 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE--PAPTTP 535 Query: 349 SAPAP 353 A AP Sbjct: 536 KAAAP 540 Score = 31.6 bits (70), Expect = 1.8 Identities = 22/65 (33%), Positives = 27/65 (41%), Gaps = 7/65 (10%) Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQP-APQLPLNAAP--PSSVPPVPPSEALPPPACP 348 +P +P P T +P TP+ AP P AP P + P P E P P P Sbjct: 470 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE--PTPTTP 527 Query: 349 SAPAP 353 PAP Sbjct: 528 EEPAP 532 Score = 31.2 bits (69), Expect = 2.4 Identities = 19/63 (30%), Positives = 25/63 (39%), Gaps = 3/63 (4%) Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQ-PAPQLPLNAAPPSSVPPVPPSEALPPPACPSA 350 +P +P P T +P TP+ P P P AP + P + P P P Sbjct: 494 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 553 Query: 351 PAP 353 PAP Sbjct: 554 PAP 556 Score = 29.6 bits (65), Expect = 7.0 Identities = 26/89 (29%), Positives = 35/89 (39%), Gaps = 20/89 (22%) Query: 284 SPLAANGQSPS----PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNA----------- 327 +P A +P+ P +P PA +T SP TP +PAP +A Sbjct: 349 APTAPKKPAPTTPKEPAPTTPKEPA-PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT 407 Query: 328 ---APPSSVPPVPPSEALPPPACPSAPAP 353 AP + P P + P P P PAP Sbjct: 408 TKSAPTTPKEPSPTTTKEPAPTTPKEPAP 436 Score = 29.3 bits (64), Expect = 9.1 Identities = 19/68 (27%), Positives = 23/68 (33%), Gaps = 8/68 (11%) Query: 294 SPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAP-----PSSVP---PVPPSEALPPP 345 +P +P P G T P P P AP P+S P P + P Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 625 Query: 346 ACPSAPAP 353 P PAP Sbjct: 626 TTPKEPAP 633 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 44.7 bits (104), Expect = 2e-04 Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 5/77 (6%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP 344 P + P+P +P G ST S +PAP P AP + P P + P Sbjct: 696 PAPTTPKKPAPKELAPTTTKGPTSTTSD-----KPAPTTPKETAPTTPKEPAPTTPKKPA 750 Query: 345 PACPSAPAPRRSIISRP 361 P P P P S +S P Sbjct: 751 PTTPETPPPTTSEVSTP 767 Score = 40.8 bits (94), Expect = 0.003 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 5/70 (7%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVPPSEALP 343 P + P+P + P +T S+P TP +PAP P AP + P P + P Sbjct: 311 PAPTTPKEPAPTTTKEPAP----TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 366 Query: 344 PPACPSAPAP 353 P P PAP Sbjct: 367 TPTTPKEPAP 376 Score = 38.9 bits (89), Expect = 0.012 Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 2/62 (3%) Query: 294 SPGSQSPVVPAGAVSTGSSSPG--TPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAP 351 +P +P P T P T +PAP P AP + P P + P P P P Sbjct: 354 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 413 Query: 352 AP 353 AP Sbjct: 414 AP 415 Score = 38.1 bits (87), Expect = 0.020 Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 12/90 (13%) Query: 284 SPLAANGQSPSPGSQSPVVPAG-AVSTGSSSPGTP---------QPAPQLPLNAAPPSSV 333 SP +P+ +P A +T S+P TP +PAP P AP + Sbjct: 422 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 481 Query: 334 PPVPPSEALPPPACPSAPAPRRSIISRPPP 363 P P + P P P PAP + +P P Sbjct: 482 KPAPTTPKEPAPTTPKEPAP--TTTKKPAP 509 Score = 38.1 bits (87), Expect = 0.020 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%) Query: 291 QSPSPGSQSPVVPAGAVSTGSSSPGTPQ-PAPQLPLNAAPPSSVPPVPPSEALPPPACPS 349 + P+P + + P + +P TP+ PAP P AAP + P P + P P P Sbjct: 545 EKPAPTTPEELAPT---TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 601 Query: 350 APAP 353 PAP Sbjct: 602 EPAP 605 Score = 36.2 bits (82), Expect = 0.075 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 3/69 (4%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP 344 P + P+P ++ P P ++P +PAP P AP + P P + P Sbjct: 366 PTPTTPKEPAPTTKEPA-PTTPKEPAPTAP--KKPAPTTPKEPAPTTPKEPAPTTTKEPS 422 Query: 345 PACPSAPAP 353 P P PAP Sbjct: 423 PTTPKEPAP 431 Score = 35.0 bits (79), Expect = 0.17 Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 4/73 (5%) Query: 284 SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPG--TP-QPAPQLPLNAAPPSSVPPVPPSE 340 +P +P+ +P P T P TP +PAP P P + P P ++ Sbjct: 320 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 379 Query: 341 ALPPPACPSAPAP 353 P P P PAP Sbjct: 380 E-PAPTTPKEPAP 391 Score = 35.0 bits (79), Expect = 0.17 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 6/76 (7%) Query: 283 ASPLAANGQSPS----PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVP 337 ++P SP+ P +P PA + +P TP +PAP P AP ++ P P Sbjct: 451 SAPTTPKEPSPTTTKEPAPTTPKEPA-PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 509 Query: 338 PSEALPPPACPSAPAP 353 + P P P AP Sbjct: 510 TTPKEPAPTTPKETAP 525 Score = 34.3 bits (77), Expect = 0.28 Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 2/59 (3%) Query: 295 PGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAP 353 P S +P P +T S+P TP+ +AP + P P + P P P PAP Sbjct: 265 PASTTPKEPTP--TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 321 Score = 34.3 bits (77), Expect = 0.28 Identities = 19/76 (25%), Positives = 28/76 (36%), Gaps = 6/76 (7%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP------QPAPQLPLNAAPPSSVPPVPP 338 P + P+P + P ++P P +PAP P AP + P Sbjct: 563 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT 622 Query: 339 SEALPPPACPSAPAPR 354 + P P P PAP+ Sbjct: 623 TLKEPAPTTPKKPAPK 638 Score = 33.9 bits (76), Expect = 0.37 Identities = 22/81 (27%), Positives = 31/81 (38%), Gaps = 11/81 (13%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTG----------SSSPGTP-QPAPQLPLNAAPPSSV 333 P + P+P +P ST ++P TP +PAP P AP + Sbjct: 627 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 686 Query: 334 PPVPPSEALPPPACPSAPAPR 354 P + P P P PAP+ Sbjct: 687 GTAPTTLKEPAPTTPKKPAPK 707 Score = 33.5 bits (75), Expect = 0.48 Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 23/90 (25%) Query: 285 PLAANGQSPSPGS--QSPVVPAG-AVSTGSSSPGTP---------QPAPQLPLNAAPPSS 332 P + + P+P + +P P A +T S+P TP +PAP P AP ++ Sbjct: 265 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 324 Query: 333 VPPVP---------PSEALPPPACPSAPAP 353 P P P E P P P PAP Sbjct: 325 KEPAPTTTKSAPTTPKE--PAPTTPKKPAP 352 Score = 32.7 bits (73), Expect = 0.82 Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 6/62 (9%) Query: 295 PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAP--PSSVPPVPPSEALPPPACPSAP 351 P +P PA +T +P TP +PAP P AP P + P P + P P P Sbjct: 491 PAPTTPKEPA-PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL--APTTPEKP 547 Query: 352 AP 353 AP Sbjct: 548 AP 549 Score = 32.0 bits (71), Expect = 1.4 Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 7/65 (10%) Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQ-PAPQLPLNAAP--PSSVPPVPPSEALPPPACP 348 +P +P P T +P TP+ PAP P AP P P P E P P P Sbjct: 519 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE--PAPTTP 576 Query: 349 SAPAP 353 A AP Sbjct: 577 KAAAP 581 Score = 31.6 bits (70), Expect = 1.8 Identities = 22/65 (33%), Positives = 27/65 (41%), Gaps = 7/65 (10%) Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQP-APQLPLNAAP--PSSVPPVPPSEALPPPACP 348 +P +P P T +P TP+ AP P AP P + P P E P P P Sbjct: 511 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE--PTPTTP 568 Query: 349 SAPAP 353 PAP Sbjct: 569 EEPAP 573 Score = 31.2 bits (69), Expect = 2.4 Identities = 19/63 (30%), Positives = 25/63 (39%), Gaps = 3/63 (4%) Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQ-PAPQLPLNAAPPSSVPPVPPSEALPPPACPSA 350 +P +P P T +P TP+ P P P AP + P + P P P Sbjct: 535 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 594 Query: 351 PAP 353 PAP Sbjct: 595 PAP 597 Score = 29.6 bits (65), Expect = 7.0 Identities = 26/89 (29%), Positives = 35/89 (39%), Gaps = 20/89 (22%) Query: 284 SPLAANGQSPS----PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNA----------- 327 +P A +P+ P +P PA +T SP TP +PAP +A Sbjct: 390 APTAPKKPAPTTPKEPAPTTPKEPA-PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT 448 Query: 328 ---APPSSVPPVPPSEALPPPACPSAPAP 353 AP + P P + P P P PAP Sbjct: 449 TKSAPTTPKEPSPTTTKEPAPTTPKEPAP 477 Score = 29.3 bits (64), Expect = 9.1 Identities = 19/68 (27%), Positives = 23/68 (33%), Gaps = 8/68 (11%) Query: 294 SPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAP-----PSSVP---PVPPSEALPPP 345 +P +P P G T P P P AP P+S P P + P Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 666 Query: 346 ACPSAPAP 353 P PAP Sbjct: 667 TTPKEPAP 674 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 44.7 bits (104), Expect = 2e-04 Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 5/77 (6%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP 344 P + P+P +P G ST S +PAP P AP + P P + P Sbjct: 748 PAPTTPKKPAPKELAPTTTKGPTSTTSD-----KPAPTTPKETAPTTPKEPAPTTPKKPA 802 Query: 345 PACPSAPAPRRSIISRP 361 P P P P S +S P Sbjct: 803 PTTPETPPPTTSEVSTP 819 Score = 40.8 bits (94), Expect = 0.003 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 5/70 (7%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVPPSEALP 343 P + P+P + P +T S+P TP +PAP P AP + P P + P Sbjct: 363 PAPTTPKEPAPTTTKEPAP----TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 418 Query: 344 PPACPSAPAP 353 P P PAP Sbjct: 419 TPTTPKEPAP 428 Score = 38.9 bits (89), Expect = 0.012 Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 2/62 (3%) Query: 294 SPGSQSPVVPAGAVSTGSSSPG--TPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAP 351 +P +P P T P T +PAP P AP + P P + P P P P Sbjct: 406 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 465 Query: 352 AP 353 AP Sbjct: 466 AP 467 Score = 38.1 bits (87), Expect = 0.020 Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 12/90 (13%) Query: 284 SPLAANGQSPSPGSQSPVVPAG-AVSTGSSSPGTP---------QPAPQLPLNAAPPSSV 333 SP +P+ +P A +T S+P TP +PAP P AP + Sbjct: 474 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 533 Query: 334 PPVPPSEALPPPACPSAPAPRRSIISRPPP 363 P P + P P P PAP + +P P Sbjct: 534 KPAPTTPKEPAPTTPKEPAP--TTTKKPAP 561 Score = 38.1 bits (87), Expect = 0.020 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%) Query: 291 QSPSPGSQSPVVPAGAVSTGSSSPGTPQ-PAPQLPLNAAPPSSVPPVPPSEALPPPACPS 349 + P+P + + P + +P TP+ PAP P AAP + P P + P P P Sbjct: 597 EKPAPTTPEELAPT---TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 653 Query: 350 APAP 353 PAP Sbjct: 654 EPAP 657 Score = 36.2 bits (82), Expect = 0.075 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 3/69 (4%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP 344 P + P+P ++ P P ++P +PAP P AP + P P + P Sbjct: 418 PTPTTPKEPAPTTKEPA-PTTPKEPAPTAP--KKPAPTTPKEPAPTTPKEPAPTTTKEPS 474 Query: 345 PACPSAPAP 353 P P PAP Sbjct: 475 PTTPKEPAP 483 Score = 35.0 bits (79), Expect = 0.17 Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 4/73 (5%) Query: 284 SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPG--TP-QPAPQLPLNAAPPSSVPPVPPSE 340 +P +P+ +P P T P TP +PAP P P + P P ++ Sbjct: 372 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 431 Query: 341 ALPPPACPSAPAP 353 P P P PAP Sbjct: 432 E-PAPTTPKEPAP 443 Score = 35.0 bits (79), Expect = 0.17 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 6/76 (7%) Query: 283 ASPLAANGQSPS----PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVP 337 ++P SP+ P +P PA + +P TP +PAP P AP ++ P P Sbjct: 503 SAPTTPKEPSPTTTKEPAPTTPKEPA-PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 561 Query: 338 PSEALPPPACPSAPAP 353 + P P P AP Sbjct: 562 TTPKEPAPTTPKETAP 577 Score = 34.3 bits (77), Expect = 0.28 Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 2/59 (3%) Query: 295 PGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAP 353 P S +P P +T S+P TP+ +AP + P P + P P P PAP Sbjct: 317 PASTTPKEPTP--TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 373 Score = 34.3 bits (77), Expect = 0.28 Identities = 19/76 (25%), Positives = 28/76 (36%), Gaps = 6/76 (7%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP------QPAPQLPLNAAPPSSVPPVPP 338 P + P+P + P ++P P +PAP P AP + P Sbjct: 615 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT 674 Query: 339 SEALPPPACPSAPAPR 354 + P P P PAP+ Sbjct: 675 TLKEPAPTTPKKPAPK 690 Score = 33.9 bits (76), Expect = 0.37 Identities = 22/81 (27%), Positives = 31/81 (38%), Gaps = 11/81 (13%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTG----------SSSPGTP-QPAPQLPLNAAPPSSV 333 P + P+P +P ST ++P TP +PAP P AP + Sbjct: 679 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 738 Query: 334 PPVPPSEALPPPACPSAPAPR 354 P + P P P PAP+ Sbjct: 739 GTAPTTLKEPAPTTPKKPAPK 759 Score = 33.5 bits (75), Expect = 0.48 Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 23/90 (25%) Query: 285 PLAANGQSPSPGS--QSPVVPAG-AVSTGSSSPGTP---------QPAPQLPLNAAPPSS 332 P + + P+P + +P P A +T S+P TP +PAP P AP ++ Sbjct: 317 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 376 Query: 333 VPPVP---------PSEALPPPACPSAPAP 353 P P P E P P P PAP Sbjct: 377 KEPAPTTTKSAPTTPKE--PAPTTPKKPAP 404 Score = 32.7 bits (73), Expect = 0.82 Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 6/62 (9%) Query: 295 PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAP--PSSVPPVPPSEALPPPACPSAP 351 P +P PA +T +P TP +PAP P AP P + P P + P P P Sbjct: 543 PAPTTPKEPA-PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL--APTTPEKP 599 Query: 352 AP 353 AP Sbjct: 600 AP 601 Score = 32.0 bits (71), Expect = 1.4 Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 7/65 (10%) Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQ-PAPQLPLNAAP--PSSVPPVPPSEALPPPACP 348 +P +P P T +P TP+ PAP P AP P P P E P P P Sbjct: 571 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE--PAPTTP 628 Query: 349 SAPAP 353 A AP Sbjct: 629 KAAAP 633 Score = 31.6 bits (70), Expect = 1.8 Identities = 22/65 (33%), Positives = 27/65 (41%), Gaps = 7/65 (10%) Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQP-APQLPLNAAP--PSSVPPVPPSEALPPPACP 348 +P +P P T +P TP+ AP P AP P + P P E P P P Sbjct: 563 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE--PTPTTP 620 Query: 349 SAPAP 353 PAP Sbjct: 621 EEPAP 625 Score = 31.2 bits (69), Expect = 2.4 Identities = 19/63 (30%), Positives = 25/63 (39%), Gaps = 3/63 (4%) Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQ-PAPQLPLNAAPPSSVPPVPPSEALPPPACPSA 350 +P +P P T +P TP+ P P P AP + P + P P P Sbjct: 587 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 646 Query: 351 PAP 353 PAP Sbjct: 647 PAP 649 Score = 29.6 bits (65), Expect = 7.0 Identities = 26/89 (29%), Positives = 35/89 (39%), Gaps = 20/89 (22%) Query: 284 SPLAANGQSPS----PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNA----------- 327 +P A +P+ P +P PA +T SP TP +PAP +A Sbjct: 442 APTAPKKPAPTTPKEPAPTTPKEPA-PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT 500 Query: 328 ---APPSSVPPVPPSEALPPPACPSAPAP 353 AP + P P + P P P PAP Sbjct: 501 TKSAPTTPKEPSPTTTKEPAPTTPKEPAP 529 Score = 29.3 bits (64), Expect = 9.1 Identities = 19/68 (27%), Positives = 23/68 (33%), Gaps = 8/68 (11%) Query: 294 SPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAP-----PSSVP---PVPPSEALPPP 345 +P +P P G T P P P AP P+S P P + P Sbjct: 659 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718 Query: 346 ACPSAPAP 353 P PAP Sbjct: 719 TTPKEPAP 726 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 44.7 bits (104), Expect = 2e-04 Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 5/77 (6%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP 344 P + P+P +P G ST S +PAP P AP + P P + P Sbjct: 789 PAPTTPKKPAPKELAPTTTKGPTSTTSD-----KPAPTTPKETAPTTPKEPAPTTPKKPA 843 Query: 345 PACPSAPAPRRSIISRP 361 P P P P S +S P Sbjct: 844 PTTPETPPPTTSEVSTP 860 Score = 40.8 bits (94), Expect = 0.003 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 5/70 (7%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVPPSEALP 343 P + P+P + P +T S+P TP +PAP P AP + P P + P Sbjct: 404 PAPTTPKEPAPTTTKEPAP----TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 459 Query: 344 PPACPSAPAP 353 P P PAP Sbjct: 460 TPTTPKEPAP 469 Score = 38.9 bits (89), Expect = 0.012 Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 2/62 (3%) Query: 294 SPGSQSPVVPAGAVSTGSSSPG--TPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAP 351 +P +P P T P T +PAP P AP + P P + P P P P Sbjct: 447 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 506 Query: 352 AP 353 AP Sbjct: 507 AP 508 Score = 38.1 bits (87), Expect = 0.020 Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 12/90 (13%) Query: 284 SPLAANGQSPSPGSQSPVVPAG-AVSTGSSSPGTP---------QPAPQLPLNAAPPSSV 333 SP +P+ +P A +T S+P TP +PAP P AP + Sbjct: 515 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 574 Query: 334 PPVPPSEALPPPACPSAPAPRRSIISRPPP 363 P P + P P P PAP + +P P Sbjct: 575 KPAPTTPKEPAPTTPKEPAP--TTTKKPAP 602 Score = 38.1 bits (87), Expect = 0.020 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%) Query: 291 QSPSPGSQSPVVPAGAVSTGSSSPGTPQ-PAPQLPLNAAPPSSVPPVPPSEALPPPACPS 349 + P+P + + P + +P TP+ PAP P AAP + P P + P P P Sbjct: 638 EKPAPTTPEELAPT---TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 694 Query: 350 APAP 353 PAP Sbjct: 695 EPAP 698 Score = 36.2 bits (82), Expect = 0.075 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 3/69 (4%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP 344 P + P+P ++ P P ++P +PAP P AP + P P + P Sbjct: 459 PTPTTPKEPAPTTKEPA-PTTPKEPAPTAP--KKPAPTTPKEPAPTTPKEPAPTTTKEPS 515 Query: 345 PACPSAPAP 353 P P PAP Sbjct: 516 PTTPKEPAP 524 Score = 35.0 bits (79), Expect = 0.17 Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 4/73 (5%) Query: 284 SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPG--TP-QPAPQLPLNAAPPSSVPPVPPSE 340 +P +P+ +P P T P TP +PAP P P + P P ++ Sbjct: 413 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 472 Query: 341 ALPPPACPSAPAP 353 P P P PAP Sbjct: 473 E-PAPTTPKEPAP 484 Score = 35.0 bits (79), Expect = 0.17 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 6/76 (7%) Query: 283 ASPLAANGQSPS----PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVP 337 ++P SP+ P +P PA + +P TP +PAP P AP ++ P P Sbjct: 544 SAPTTPKEPSPTTTKEPAPTTPKEPA-PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 602 Query: 338 PSEALPPPACPSAPAP 353 + P P P AP Sbjct: 603 TTPKEPAPTTPKETAP 618 Score = 34.3 bits (77), Expect = 0.28 Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 2/59 (3%) Query: 295 PGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAP 353 P S +P P +T S+P TP+ +AP + P P + P P P PAP Sbjct: 358 PASTTPKEPTP--TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 414 Score = 34.3 bits (77), Expect = 0.28 Identities = 19/76 (25%), Positives = 28/76 (36%), Gaps = 6/76 (7%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP------QPAPQLPLNAAPPSSVPPVPP 338 P + P+P + P ++P P +PAP P AP + P Sbjct: 656 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT 715 Query: 339 SEALPPPACPSAPAPR 354 + P P P PAP+ Sbjct: 716 TLKEPAPTTPKKPAPK 731 Score = 33.9 bits (76), Expect = 0.37 Identities = 22/81 (27%), Positives = 31/81 (38%), Gaps = 11/81 (13%) Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTG----------SSSPGTP-QPAPQLPLNAAPPSSV 333 P + P+P +P ST ++P TP +PAP P AP + Sbjct: 720 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 779 Query: 334 PPVPPSEALPPPACPSAPAPR 354 P + P P P PAP+ Sbjct: 780 GTAPTTLKEPAPTTPKKPAPK 800 Score = 33.5 bits (75), Expect = 0.48 Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 23/90 (25%) Query: 285 PLAANGQSPSPGS--QSPVVPAG-AVSTGSSSPGTP---------QPAPQLPLNAAPPSS 332 P + + P+P + +P P A +T S+P TP +PAP P AP ++ Sbjct: 358 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 417 Query: 333 VPPVP---------PSEALPPPACPSAPAP 353 P P P E P P P PAP Sbjct: 418 KEPAPTTTKSAPTTPKE--PAPTTPKKPAP 445 Score = 32.7 bits (73), Expect = 0.82 Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 6/62 (9%) Query: 295 PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAP--PSSVPPVPPSEALPPPACPSAP 351 P +P PA +T +P TP +PAP P AP P + P P + P P P Sbjct: 584 PAPTTPKEPA-PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL--APTTPEKP 640 Query: 352 AP 353 AP Sbjct: 641 AP 642 Score = 32.0 bits (71), Expect = 1.4 Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 7/65 (10%) Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQ-PAPQLPLNAAP--PSSVPPVPPSEALPPPACP 348 +P +P P T +P TP+ PAP P AP P P P E P P P Sbjct: 612 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE--PAPTTP 669 Query: 349 SAPAP 353 A AP Sbjct: 670 KAAAP 674 Score = 31.6 bits (70), Expect = 1.8 Identities = 22/65 (33%), Positives = 27/65 (41%), Gaps = 7/65 (10%) Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQP-APQLPLNAAP--PSSVPPVPPSEALPPPACP 348 +P +P P T +P TP+ AP P AP P + P P E P P P Sbjct: 604 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE--PTPTTP 661 Query: 349 SAPAP 353 PAP Sbjct: 662 EEPAP 666 Score = 31.2 bits (69), Expect = 2.4 Identities = 19/63 (30%), Positives = 25/63 (39%), Gaps = 3/63 (4%) Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQ-PAPQLPLNAAPPSSVPPVPPSEALPPPACPSA 350 +P +P P T +P TP+ P P P AP + P + P P P Sbjct: 628 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 687 Query: 351 PAP 353 PAP Sbjct: 688 PAP 690 Score = 29.6 bits (65), Expect = 7.0 Identities = 26/89 (29%), Positives = 35/89 (39%), Gaps = 20/89 (22%) Query: 284 SPLAANGQSPS----PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNA----------- 327 +P A +P+ P +P PA +T SP TP +PAP +A Sbjct: 483 APTAPKKPAPTTPKEPAPTTPKEPA-PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT 541 Query: 328 ---APPSSVPPVPPSEALPPPACPSAPAP 353 AP + P P + P P P PAP Sbjct: 542 TKSAPTTPKEPSPTTTKEPAPTTPKEPAP 570 Score = 29.3 bits (64), Expect = 9.1 Identities = 19/68 (27%), Positives = 23/68 (33%), Gaps = 8/68 (11%) Query: 294 SPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAP-----PSSVP---PVPPSEALPPP 345 +P +P P G T P P P AP P+S P P + P Sbjct: 700 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759 Query: 346 ACPSAPAP 353 P PAP Sbjct: 760 TTPKEPAP 767 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.136 0.434 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,642,348 Number of Sequences: 37866 Number of extensions: 1488942 Number of successful extensions: 26750 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 517 Number of HSP's successfully gapped in prelim test: 1407 Number of HSP's that attempted gapping in prelim test: 11892 Number of HSP's gapped (non-prelim): 9636 length of query: 520 length of database: 18,247,518 effective HSP length: 107 effective length of query: 413 effective length of database: 14,195,856 effective search space: 5862888528 effective search space used: 5862888528 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.