Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 186700625

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|186700625 Rab-like GTP-binding protein 1 isoform 2 [Homo
sapiens]
         (520 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|186700625 Rab-like GTP-binding protein 1 isoform 2 [Homo sapi...  1084   0.0  
gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi...   735   0.0  
gi|157168329 formin 1 [Homo sapiens]                                   54   5e-07
gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo sap...    50   7e-06
gi|40548415 dishevelled associated activator of morphogenesis 2 ...    49   1e-05
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     49   1e-05
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     49   1e-05
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    49   1e-05
gi|5453555 ras-related nuclear protein [Homo sapiens]                  48   2e-05
gi|7662302 TBK1 binding protein 1 [Homo sapiens]                       47   4e-05
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     47   4e-05
gi|237757312 synaptojanin 1 isoform c [Homo sapiens]                   46   7e-05
gi|237757310 synaptojanin 1 isoform a [Homo sapiens]                   46   7e-05
gi|237757308 synaptojanin 1 isoform b [Homo sapiens]                   46   7e-05
gi|237757326 synaptojanin 1 isoform d [Homo sapiens]                   46   7e-05
gi|34147513 RAB7, member RAS oncogene family [Homo sapiens]            46   7e-05
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    46   9e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    46   9e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    46   9e-05
gi|4758996 Ras-related protein Rab-33A [Homo sapiens]                  46   9e-05
gi|33356148 formin-like 1 [Homo sapiens]                               46   9e-05
gi|7661922 RAB21, member RAS oncogene family [Homo sapiens]            45   1e-04
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         45   2e-04
gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]                     45   2e-04
gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]                     45   2e-04
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             45   2e-04
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   45   2e-04
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   45   2e-04
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   45   2e-04
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    45   2e-04

>gi|186700625 Rab-like GTP-binding protein 1 isoform 2 [Homo
           sapiens]
          Length = 520

 Score = 1084 bits (2804), Expect = 0.0
 Identities = 520/520 (100%), Positives = 520/520 (100%)

Query: 1   MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALW 60
           MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALW
Sbjct: 1   MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALW 60

Query: 61  HRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDP 120
           HRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDP
Sbjct: 61  HRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDP 120

Query: 121 QEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDM 180
           QEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDM
Sbjct: 121 QEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDM 180

Query: 181 GEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLL 240
           GEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLL
Sbjct: 181 GEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLL 240

Query: 241 RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP 300
           RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP
Sbjct: 241 RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP 300

Query: 301 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR 360
           VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR
Sbjct: 301 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR 360

Query: 361 PPPWGWRLRGALGRRGQWPPWGGGRACHCLGRHLPLYHRLCRCPVAAVCASELEEAGHWW 420
           PPPWGWRLRGALGRRGQWPPWGGGRACHCLGRHLPLYHRLCRCPVAAVCASELEEAGHWW
Sbjct: 361 PPPWGWRLRGALGRRGQWPPWGGGRACHCLGRHLPLYHRLCRCPVAAVCASELEEAGHWW 420

Query: 421 SPGWALQVLGLQAQCEPALQEGRGQLASARLGGHPGPLGAEPPVFLRDVTEAQEGPVRVC 480
           SPGWALQVLGLQAQCEPALQEGRGQLASARLGGHPGPLGAEPPVFLRDVTEAQEGPVRVC
Sbjct: 421 SPGWALQVLGLQAQCEPALQEGRGQLASARLGGHPGPLGAEPPVFLRDVTEAQEGPVRVC 480

Query: 481 LQRLGRGRLAVGCALPRHLLALRAHLGPQHAYGSASGREP 520
           LQRLGRGRLAVGCALPRHLLALRAHLGPQHAYGSASGREP
Sbjct: 481 LQRLGRGRLAVGCALPRHLLALRAHLGPQHAYGSASGREP 520


>gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo
           sapiens]
          Length = 729

 Score =  735 bits (1897), Expect = 0.0
 Identities = 360/360 (100%), Positives = 360/360 (100%)

Query: 1   MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALW 60
           MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALW
Sbjct: 1   MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALW 60

Query: 61  HRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDP 120
           HRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDP
Sbjct: 61  HRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDP 120

Query: 121 QEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDM 180
           QEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDM
Sbjct: 121 QEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDM 180

Query: 181 GEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLL 240
           GEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLL
Sbjct: 181 GEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLL 240

Query: 241 RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP 300
           RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP
Sbjct: 241 RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP 300

Query: 301 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR 360
           VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR
Sbjct: 301 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR 360


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 51/161 (31%), Positives = 69/161 (42%), Gaps = 20/161 (12%)

Query: 225 KFFNIPFLQLQRETLLRQLET-------NQLDMD----ATLEELSVQQETEDQNYGIF-L 272
           K F    +Q  RET L+  E+       NQL       ++L +LS   + +D +  +  +
Sbjct: 575 KTFRNVCVQTDRETFLKPCESESKTTRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPM 634

Query: 273 EMMEARSRGHASPLAANGQSPSP-----GSQSPVVPAGAVSTGSSSPGTPQPAPQLP--L 325
           E M +  +    P  A+   P P     GS SP  P   VS G   P  P P P LP   
Sbjct: 635 EGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPS 694

Query: 326 NAAPPSSVPPVP-PSEALPPPACPSAPAPRRSIISRPPPWG 365
           +A PP   PP P P+   PP      PAP    ++ PPP G
Sbjct: 695 SAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPG 735


>gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo
           sapiens]
          Length = 205

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 39/182 (21%), Positives = 83/182 (45%), Gaps = 39/182 (21%)

Query: 42  YNMKIVIRGDRNTGKTALWHRLQGRPFVEEYIPT--QEIQVTSIHWSYKTTDDIVKVEVW 99
           Y  K+++ GD   GK+ L  R     + E YI T   + ++ +I    KT    +K+++W
Sbjct: 10  YLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKT----IKLQIW 65

Query: 100 DVVDKGKCKKRGDGLKMENDPQEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYIL 159
           D   + + +                    + + +   Y+  +G+++++D+T Q +FN + 
Sbjct: 66  DTAGQERFR-------------------TITSSY---YRGAHGIIVVYDVTDQESFNNVK 103

Query: 160 RELPKVPTH----VPVCVLGNYRDMGEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMK 215
           + L ++  +    V   ++GN  D+   +V+     ++F D+L  P       + E+S K
Sbjct: 104 QWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIP-------FLETSAK 156

Query: 216 NS 217
           N+
Sbjct: 157 NA 158


>gi|40548415 dishevelled associated activator of morphogenesis 2
           [Homo sapiens]
          Length = 1067

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 37/115 (32%), Positives = 49/115 (42%), Gaps = 5/115 (4%)

Query: 239 LLRQLETNQLDMDA-TLEELSVQQETEDQNYGIFLEMMEAR-SRGHASPLAANGQSPSPG 296
           L+ +LE  + + +  TLE+  + +        +  E  E R +RG  + L A     S G
Sbjct: 458 LVSRLERKERECETKTLEKEEMMRTLNKMKDKLARESQELRQARGQVAELVAQLSELSTG 517

Query: 297 SQSPVVPAGAVSTGSSSPGT---PQPAPQLPLNAAPPSSVPPVPPSEALPPPACP 348
             S   P G   T SSS  T   P P P LP    PP   PP+PP     PP  P
Sbjct: 518 PVSSPPPPGGPLTLSSSMTTNDLPPPPPPLPFACCPPPPPPPLPPGGPPTPPGAP 572


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 38/125 (30%), Positives = 58/125 (46%), Gaps = 10/125 (8%)

Query: 241 RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP 300
           +Q+ T + D++A + +L+ +         +  E+ +A+    +   AA    PS  S++P
Sbjct: 519 QQIATEKQDLEAEVSQLTGEVAK------LTKELEDAKKEMASLSAAAITVPPSVPSRAP 572

Query: 301 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAP--APRRSII 358
           V PA  +   S +   P PAP       PP   PP PP   LP   C S+P   P  + I
Sbjct: 573 VPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPP--PLPGGVCISSPPSLPGGTAI 630

Query: 359 SRPPP 363
           S PPP
Sbjct: 631 SPPPP 635



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 10/82 (12%)

Query: 285 PLAANGQSPSPGSQSPVVPAGA-VSTGSSSPGTPQ--PAPQLPLNAAPPSSVPPVPPSEA 341
           PL+ +   P P    P +P G  + + SS PG     P P LP +A  P   PP+P S  
Sbjct: 635 PLSGDATIPPP----PPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAG 690

Query: 342 LPPPACPSAPAPRRSIISRPPP 363
           +PP   P  P P  + +  PPP
Sbjct: 691 IPP---PPPPLPGEAGMPPPPP 709



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 8/84 (9%)

Query: 293 PSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP----PACP 348
           P PGS + + P      GS+  G P P P LP  A  P   PP+P    +PP    P  P
Sbjct: 671 PLPGS-ARIPPPPPPLPGSA--GIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 727

Query: 349 SAPAPRRSI-ISRPPPWGWRLRGA 371
             P P   + +  PPP+G+ +  A
Sbjct: 728 GIPPPPPGMGMPPPPPFGFGVPAA 751



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 30/86 (34%), Positives = 37/86 (43%), Gaps = 15/86 (17%)

Query: 285 PLAANGQSPSPGSQSPVVPAG-AVSTGSSSPGT---PQPAPQLPLNAAPPSSVPPVPPSE 340
           PL      PSP S    +P G A+      PG+   P P P LP +A  P   PP+P   
Sbjct: 647 PLPEGVGIPSPSS----LPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEA 702

Query: 341 ALPPPA--CPSAPAPRRSIISRPPPW 364
            +PPP    P  P      I  PPP+
Sbjct: 703 GMPPPPPPLPGGPG-----IPPPPPF 723



 Score = 36.2 bits (82), Expect = 0.075
 Identities = 37/118 (31%), Positives = 44/118 (37%), Gaps = 32/118 (27%)

Query: 293 PSPGSQSPVVPAGA-VSTGSSSPG--------------TPQPAPQLPLNAAPPS------ 331
           P P    P +P G  +S+  S PG              T  P P LP     PS      
Sbjct: 603 PPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG 662

Query: 332 --SVPPVPP---SEALPPPACPSAPAPRRSIISRPPPWGWRLRGALGRRGQWPPWGGG 384
             ++PP PP   S  +PP   P  P P  + I  PPP    L G  G     PP  GG
Sbjct: 663 GTAIPPPPPLPGSARIPP---PPPPLPGSAGIPPPPP---PLPGEAGMPPPPPPLPGG 714


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 38/125 (30%), Positives = 58/125 (46%), Gaps = 10/125 (8%)

Query: 241 RQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSP 300
           +Q+ T + D++A + +L+ +         +  E+ +A+    +   AA    PS  S++P
Sbjct: 528 QQIATEKQDLEAEVSQLTGEVAK------LTKELEDAKKEMASLSAAAITVPPSVPSRAP 581

Query: 301 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAP--APRRSII 358
           V PA  +   S +   P PAP       PP   PP PP   LP   C S+P   P  + I
Sbjct: 582 VPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPP--PLPGGVCISSPPSLPGGTAI 639

Query: 359 SRPPP 363
           S PPP
Sbjct: 640 SPPPP 644



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 10/82 (12%)

Query: 285 PLAANGQSPSPGSQSPVVPAGA-VSTGSSSPGTPQ--PAPQLPLNAAPPSSVPPVPPSEA 341
           PL+ +   P P    P +P G  + + SS PG     P P LP +A  P   PP+P S  
Sbjct: 644 PLSGDATIPPP----PPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAG 699

Query: 342 LPPPACPSAPAPRRSIISRPPP 363
           +PP   P  P P  + +  PPP
Sbjct: 700 IPP---PPPPLPGEAGMPPPPP 718



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 8/84 (9%)

Query: 293 PSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP----PACP 348
           P PGS + + P      GS+  G P P P LP  A  P   PP+P    +PP    P  P
Sbjct: 680 PLPGS-ARIPPPPPPLPGSA--GIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 736

Query: 349 SAPAPRRSI-ISRPPPWGWRLRGA 371
             P P   + +  PPP+G+ +  A
Sbjct: 737 GIPPPPPGMGMPPPPPFGFGVPAA 760



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 30/86 (34%), Positives = 37/86 (43%), Gaps = 15/86 (17%)

Query: 285 PLAANGQSPSPGSQSPVVPAG-AVSTGSSSPGT---PQPAPQLPLNAAPPSSVPPVPPSE 340
           PL      PSP S    +P G A+      PG+   P P P LP +A  P   PP+P   
Sbjct: 656 PLPEGVGIPSPSS----LPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEA 711

Query: 341 ALPPPA--CPSAPAPRRSIISRPPPW 364
            +PPP    P  P      I  PPP+
Sbjct: 712 GMPPPPPPLPGGPG-----IPPPPPF 732



 Score = 36.2 bits (82), Expect = 0.075
 Identities = 37/118 (31%), Positives = 44/118 (37%), Gaps = 32/118 (27%)

Query: 293 PSPGSQSPVVPAGA-VSTGSSSPG--------------TPQPAPQLPLNAAPPS------ 331
           P P    P +P G  +S+  S PG              T  P P LP     PS      
Sbjct: 612 PPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG 671

Query: 332 --SVPPVPP---SEALPPPACPSAPAPRRSIISRPPPWGWRLRGALGRRGQWPPWGGG 384
             ++PP PP   S  +PP   P  P P  + I  PPP    L G  G     PP  GG
Sbjct: 672 GTAIPPPPPLPGSARIPP---PPPPLPGSAGIPPPPP---PLPGEAGMPPPPPPLPGG 723


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 42/134 (31%), Positives = 51/134 (38%), Gaps = 21/134 (15%)

Query: 283 ASPLAANGQSPSPG---------SQSPVVPAGAVSTGSSSPG-TPQPAPQL---PLNAAP 329
           + P+ A G  P+PG         S  P  P  + +   S PG TP P P +   P  A P
Sbjct: 107 SKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPP 166

Query: 330 P----SSVPPVPPSEALPPPACPSAPAPRRSIISRPPPWGWRLRGALGRRGQWPPWGGGR 385
           P    S VP  PP    PPP   + P P       P P G +     G+    P  GGG 
Sbjct: 167 PTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPK----GGKMPGGPKPGGGP 222

Query: 386 ACHCLGRHLPLYHR 399
                G H    HR
Sbjct: 223 GLSTPGGHPKPPHR 236



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 18/86 (20%)

Query: 282 HASPLAANGQSPSP-GSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPP--SSVPPV-P 337
           H  P       P P  S  PVV  G           P PAP +   +APP  SS PP  P
Sbjct: 90  HPQPHQQQQPPPPPQDSSKPVVAQG-----------PGPAPGV--GSAPPASSSAPPATP 136

Query: 338 PSEALPPPACPS-APAPRRSIISRPP 362
           P+   PP + P   P P  ++ S PP
Sbjct: 137 PTSGAPPGSGPGPTPTPPPAVTSAPP 162



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 22/80 (27%), Positives = 26/80 (32%), Gaps = 8/80 (10%)

Query: 290 GQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPP-------SSVPPVPPSEAL 342
           G  P      P +P          P   QP PQ P    PP          PP PP ++ 
Sbjct: 48  GPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDS- 106

Query: 343 PPPACPSAPAPRRSIISRPP 362
             P     P P   + S PP
Sbjct: 107 SKPVVAQGPGPAPGVGSAPP 126



 Score = 33.9 bits (76), Expect = 0.37
 Identities = 19/59 (32%), Positives = 23/59 (38%), Gaps = 5/59 (8%)

Query: 310 GSSSPGTPQPAPQLPLNAAPPSSV-----PPVPPSEALPPPACPSAPAPRRSIISRPPP 363
           G   PG  Q  P+ P+   PP        P  PP +  PP   P  P P +     PPP
Sbjct: 45  GPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPP 103


>gi|5453555 ras-related nuclear protein [Homo sapiens]
          Length = 216

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 48/202 (23%), Positives = 81/202 (40%), Gaps = 43/202 (21%)

Query: 41  QYNMKIVIRGDRNTGKTALWHRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWD 100
           Q   K+V+ GD  TGKT    R     F ++Y+ T  ++V  +   + T    +K  VWD
Sbjct: 8   QVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPL--VFHTNRGPIKFNVWD 65

Query: 101 VVDKGKCKKRGDGLKMENDPQEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYI-- 158
              + K     DG                       Y      ++MFD+T + T+  +  
Sbjct: 66  TAGQEKFGGLRDG----------------------YYIQAQCAIIMFDVTSRVTYKNVPN 103

Query: 159 -LRELPKVPTHVPVCVLGNYRDMGEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNS 217
             R+L +V  ++P+ + GN  D+ + +V     V     NL         +Y + S K++
Sbjct: 104 WHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNL---------QYYDISAKSN 154

Query: 218 FGLKYLHKFFNIPFLQLQRETL 239
           +        F  PFL L R+ +
Sbjct: 155 YN-------FEKPFLWLARKLI 169


>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
          Length = 615

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 35/105 (33%), Positives = 43/105 (40%), Gaps = 17/105 (16%)

Query: 276 EARSRGHASPLAANGQSPSPGSQSPVVPAGAVST---------GSSSPGTPQPAPQLPLN 326
           +ARS G      +   SP+P   SP  PA A               SP  P P+PQ   +
Sbjct: 326 QARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRS 385

Query: 327 AAPPSSVPPVPPSEALPPPACPSAPAPRRSII--------SRPPP 363
            A PS   PVP   +  PP+C S    RRS +         RPPP
Sbjct: 386 PASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPP 430



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 47/195 (24%), Positives = 62/195 (31%), Gaps = 62/195 (31%)

Query: 283 ASPLAANGQSPSPGSQSPVVPAGAVSTGSS--SPGTPQPAPQ------------------ 322
           A+P     QSP P  +SPV P  +     S  SP  P P PQ                  
Sbjct: 356 AAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRS 415

Query: 323 -LPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR---PPPWGWRLRGALGRR--- 375
            +P +   P   PP PP            P   R++  R    PP      G  GRR   
Sbjct: 416 PVPPSCPAPQPRPPPPP------------PPGERTLAERAYAKPPSHHVKAGFQGRRSYS 463

Query: 376 ---------GQWPPWGGGRACHCLGRHLPLYHRLCRCPVAAVCASELEEAGHWWSPGWAL 426
                    G  PPW              L       P      SEL   G   SP  A 
Sbjct: 464 ELAEGAAYAGASPPW--------------LQAEAATLPKPRAYGSELYGPGRPLSPRRAF 509

Query: 427 QVLGLQAQCEPALQE 441
           + + L+ + +P+ ++
Sbjct: 510 EGIRLRFEKQPSEED 524


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 36/115 (31%), Positives = 43/115 (37%), Gaps = 33/115 (28%)

Query: 280 RGHASPLAANGQSPSPGSQSPVVP------------AGAVSTGSSSPGTPQPAPQL---- 323
           RG  +  AA    P+P    P  P            A A +T   SPG  QP P+     
Sbjct: 116 RGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAA 175

Query: 324 ------PLNAAPPSSVPPVPPSEALPP---------PACPSAPAPRRSIISRPPP 363
                 P  AAPP+  PP  P  A PP         P  P  PAP +    +PPP
Sbjct: 176 PLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQ--QQPPP 228



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 10/87 (11%)

Query: 287 AANGQSPSPGSQSPVVP-----AGAVSTGSSSPGTPQPAPQ-LPLNAAPPSSVPPVPPSE 340
           AA  Q P  G+  P  P     A A +  ++ P TP P P   P+ AA P+  P    + 
Sbjct: 96  AARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAA 155

Query: 341 ALPPPAC-PSAPAP---RRSIISRPPP 363
           A  PP+  P+ P P   R + ++ PPP
Sbjct: 156 ATAPPSPGPAQPGPRAQRAAPLAAPPP 182



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 28/91 (30%), Positives = 34/91 (37%), Gaps = 16/91 (17%)

Query: 277 ARSRGHASPLAANGQSPSPGSQSP------------VVPAGAVSTGSSSPGTPQPAPQLP 324
           A +R   +  AA    PSPG   P              PA A     + P  P+ AP   
Sbjct: 144 APARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPA 203

Query: 325 LNAA----PPSSVPPVPPSEALPPPACPSAP 351
           + A     PP   PP PP +  PPP  P  P
Sbjct: 204 VAAREPPLPPPPQPPAPPQQQQPPPPQPQPP 234



 Score = 36.6 bits (83), Expect = 0.057
 Identities = 29/101 (28%), Positives = 39/101 (38%), Gaps = 22/101 (21%)

Query: 284 SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSS----------- 332
           +P AA   + +P S  P  P G  +  ++    P PAP  P   APP+            
Sbjct: 148 APRAAAAAATAPPSPGPAQP-GPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAA 206

Query: 333 ----VPPVPPSEALPPPACPSAPAPRRSIISRPPPWGWRLR 369
               +PP P   A P    P  P P      +PPP G  +R
Sbjct: 207 REPPLPPPPQPPAPPQQQQPPPPQP------QPPPEGGAVR 241



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 22/64 (34%), Positives = 27/64 (42%), Gaps = 4/64 (6%)

Query: 283 ASPLAANGQSPS--PGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSE 340
           A+PLAA   +P+  P    P  P  A     ++   P P P  P   APP    P PP  
Sbjct: 174 AAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQP--PAPPQQQQPPPPQP 231

Query: 341 ALPP 344
             PP
Sbjct: 232 QPPP 235


>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
          Length = 1295

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 33/101 (32%), Positives = 46/101 (45%), Gaps = 20/101 (19%)

Query: 282  HASPLAANGQSPSPGS-------QSPVVPAGAVST--------GSSSPGTPQPAPQLPLN 326
            H  P +++G   SP S       QSP +  G V +         S +PG P  A   P++
Sbjct: 1029 HLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS-AQSSPID 1087

Query: 327  AAPPSSVPPVPPSEAL----PPPACPSAPAPRRSIISRPPP 363
            A P + +P   P++ L    PPP  P AP  R +   RPPP
Sbjct: 1088 AQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPP 1128



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 41/150 (27%), Positives = 55/150 (36%), Gaps = 16/150 (10%)

Query: 249  DMDATLEELSVQQETEDQNYGIFLEMMEA-RSRGHASPLAANGQSPS-------PGSQSP 300
            D  A +EEL  Q      + G+      + R+    SP  + G  PS         S++P
Sbjct: 1017 DYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTP 1076

Query: 301  VVPAGAVSTGSSSPGTPQPA--PQLPLNAAPPSSVPPVPPSE------ALPPPACPSAPA 352
              P+   S   + P TP P   P  PL    P    PV P          PPP+   +PA
Sbjct: 1077 GPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPA 1136

Query: 353  PRRSIISRPPPWGWRLRGALGRRGQWPPWG 382
            P R     P   G   +  +GR    P  G
Sbjct: 1137 PTRKEFGAPKSPGTTRKDNIGRSQPSPQAG 1166



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 9/81 (11%)

Query: 291  QSPSPGSQSPVVPAGAVSTGSSSPG-TPQPAPQLPLNAAPPSSVPPVPPSEALPPPACP- 348
            QS +  S   + P     T  +S G T  P P  P  A PP S  P PP++ L  P  P 
Sbjct: 1193 QSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLP-PPAQRLQEPLVPV 1251

Query: 349  ------SAPAPRRSIISRPPP 363
                  S P P      +PPP
Sbjct: 1252 AAPMPQSGPQPNLETPPQPPP 1272


>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
          Length = 1612

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 33/101 (32%), Positives = 46/101 (45%), Gaps = 20/101 (19%)

Query: 282  HASPLAANGQSPSPGS-------QSPVVPAGAVST--------GSSSPGTPQPAPQLPLN 326
            H  P +++G   SP S       QSP +  G V +         S +PG P  A   P++
Sbjct: 1068 HLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS-AQSSPID 1126

Query: 327  AAPPSSVPPVPPSEAL----PPPACPSAPAPRRSIISRPPP 363
            A P + +P   P++ L    PPP  P AP  R +   RPPP
Sbjct: 1127 AQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPP 1167



 Score = 37.7 bits (86), Expect = 0.026
 Identities = 40/136 (29%), Positives = 53/136 (38%), Gaps = 19/136 (13%)

Query: 249  DMDATLEELSVQQETEDQNYGIFLEMMEA-RSRGHASPLAANGQSPS-------PGSQSP 300
            D  A +EEL  Q      + G+      + R+    SP  + G  PS         S++P
Sbjct: 1056 DYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTP 1115

Query: 301  VVPAGAVSTGSSSPGTPQPA--PQLPLNAA-PPSSVPPVPPSEALPP-----PACPSAPA 352
              P+   S   + P TP P   P  PL    PP   P  PP+   PP     P+   +PA
Sbjct: 1116 GPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPA 1175

Query: 353  PRRSI---ISRPPPWG 365
            P R     I  PP  G
Sbjct: 1176 PTRKEFGGIGAPPSPG 1191



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 9/81 (11%)

Query: 291  QSPSPGSQSPVVPAGAVSTGSSSPG-TPQPAPQLPLNAAPPSSVPPVPPSEALPPPACP- 348
            QS +  S   + P     T  +S G T  P P  P  A PP S  P PP++ L  P  P 
Sbjct: 1248 QSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLP-PPAQRLQEPLVPV 1306

Query: 349  ------SAPAPRRSIISRPPP 363
                  S P P      +PPP
Sbjct: 1307 AAPMPQSGPQPNLETPPQPPP 1327



 Score = 30.8 bits (68), Expect = 3.1
 Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 10/89 (11%)

Query: 264  EDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSS---PGTPQPA 320
            E++++G+     + +S+   S L  N  S   GS   +       T  S    P    P 
Sbjct: 1525 EEEDFGV-----KGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPP 1579

Query: 321  PQLPLNAAPPSSVPPVPPSEALPPPACPS 349
            P +PL   PP + PPV P   L   A P+
Sbjct: 1580 PPVPL--LPPGTSPPVDPFTTLASKASPT 1606


>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
          Length = 1350

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 33/101 (32%), Positives = 46/101 (45%), Gaps = 20/101 (19%)

Query: 282  HASPLAANGQSPSPGS-------QSPVVPAGAVST--------GSSSPGTPQPAPQLPLN 326
            H  P +++G   SP S       QSP +  G V +         S +PG P  A   P++
Sbjct: 1068 HLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS-AQSSPID 1126

Query: 327  AAPPSSVPPVPPSEAL----PPPACPSAPAPRRSIISRPPP 363
            A P + +P   P++ L    PPP  P AP  R +   RPPP
Sbjct: 1127 AQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPP 1167



 Score = 37.7 bits (86), Expect = 0.026
 Identities = 40/136 (29%), Positives = 53/136 (38%), Gaps = 19/136 (13%)

Query: 249  DMDATLEELSVQQETEDQNYGIFLEMMEA-RSRGHASPLAANGQSPS-------PGSQSP 300
            D  A +EEL  Q      + G+      + R+    SP  + G  PS         S++P
Sbjct: 1056 DYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTP 1115

Query: 301  VVPAGAVSTGSSSPGTPQPA--PQLPLNAA-PPSSVPPVPPSEALPP-----PACPSAPA 352
              P+   S   + P TP P   P  PL    PP   P  PP+   PP     P+   +PA
Sbjct: 1116 GPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPA 1175

Query: 353  PRRSI---ISRPPPWG 365
            P R     I  PP  G
Sbjct: 1176 PTRKEFGGIGAPPSPG 1191



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 9/81 (11%)

Query: 291  QSPSPGSQSPVVPAGAVSTGSSSPG-TPQPAPQLPLNAAPPSSVPPVPPSEALPPPACP- 348
            QS +  S   + P     T  +S G T  P P  P  A PP S  P PP++ L  P  P 
Sbjct: 1248 QSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLP-PPAQRLQEPLVPV 1306

Query: 349  ------SAPAPRRSIISRPPP 363
                  S P P      +PPP
Sbjct: 1307 AAPMPQSGPQPNLETPPQPPP 1327


>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
          Length = 1526

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 33/101 (32%), Positives = 46/101 (45%), Gaps = 20/101 (19%)

Query: 282  HASPLAANGQSPSPGS-------QSPVVPAGAVST--------GSSSPGTPQPAPQLPLN 326
            H  P +++G   SP S       QSP +  G V +         S +PG P  A   P++
Sbjct: 1024 HLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS-AQSSPID 1082

Query: 327  AAPPSSVPPVPPSEAL----PPPACPSAPAPRRSIISRPPP 363
            A P + +P   P++ L    PPP  P AP  R +   RPPP
Sbjct: 1083 AQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPP 1123



 Score = 37.0 bits (84), Expect = 0.044
 Identities = 36/125 (28%), Positives = 48/125 (38%), Gaps = 14/125 (11%)

Query: 249  DMDATLEELSVQQETEDQNYGIFLEMMEA-RSRGHASPLAANGQSPS-------PGSQSP 300
            D  A +EEL  Q      + G+      + R+    SP  + G  PS         S++P
Sbjct: 1012 DYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTP 1071

Query: 301  VVPAGAVSTGSSSPGTPQPA--PQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSII 358
              P+   S   + P TP P   P  PL    P    PV P     PP  P  P+ R    
Sbjct: 1072 GPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGR---- 1127

Query: 359  SRPPP 363
            S+P P
Sbjct: 1128 SQPSP 1132



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 9/81 (11%)

Query: 291  QSPSPGSQSPVVPAGAVSTGSSSPG-TPQPAPQLPLNAAPPSSVPPVPPSEALPPPACP- 348
            QS +  S   + P     T  +S G T  P P  P  A PP S  P PP++ L  P  P 
Sbjct: 1162 QSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLP-PPAQRLQEPLVPV 1220

Query: 349  ------SAPAPRRSIISRPPP 363
                  S P P      +PPP
Sbjct: 1221 AAPMPQSGPQPNLETPPQPPP 1241



 Score = 30.8 bits (68), Expect = 3.1
 Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 10/89 (11%)

Query: 264  EDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSS---PGTPQPA 320
            E++++G+     + +S+   S L  N  S   GS   +       T  S    P    P 
Sbjct: 1439 EEEDFGV-----KGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPP 1493

Query: 321  PQLPLNAAPPSSVPPVPPSEALPPPACPS 349
            P +PL   PP + PPV P   L   A P+
Sbjct: 1494 PPVPL--LPPGTSPPVDPFTTLASKASPT 1520


>gi|34147513 RAB7, member RAS oncogene family [Homo sapiens]
          Length = 207

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 32/150 (21%), Positives = 62/150 (41%), Gaps = 32/150 (21%)

Query: 44  MKIVIRGDRNTGKTALWHRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVD 103
           +K++I GD   GKT+L ++   + F  +Y  T  I    +       D +V +++WD   
Sbjct: 9   LKVIILGDSGVGKTSLMNQYVNKKFSNQYKAT--IGADFLTKEVMVDDRLVTMQIWDTAG 66

Query: 104 KGKCKKRGDGLKMENDPQEAESEMALDAEFLDVYKNCNGVVMMFDIT--------KQWTF 155
           + + +  G                      +  Y+  +  V++FD+T          W  
Sbjct: 67  QERFQSLG----------------------VAFYRGADCCVLVFDVTAPNTFKTLDSWRD 104

Query: 156 NYILRELPKVPTHVPVCVLGNYRDMGEHRV 185
            ++++  P+ P + P  VLGN  D+   +V
Sbjct: 105 EFLIQASPRDPENFPFVVLGNKIDLENRQV 134


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 31/89 (34%), Positives = 37/89 (41%), Gaps = 2/89 (2%)

Query: 277 ARSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPV 336
           AR RG   P  +   + +P    P  P+ AV     +   P P P LP +A  PS  PP 
Sbjct: 304 ARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSA--PSGPPPP 361

Query: 337 PPSEALPPPACPSAPAPRRSIISRPPPWG 365
           PPS     P  P  P P       PPP G
Sbjct: 362 PPSVLGVGPVAPPPPPPPPPPPGPPPPPG 390



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 38/128 (29%), Positives = 46/128 (35%), Gaps = 11/128 (8%)

Query: 246 NQLDMDATLEELSVQQETEDQNYGIF-----LEMMEARSRGHASPLAANGQSPSPGSQSP 300
           N  DM    E     +ET    Y        +E ++   R  A P     +   P    P
Sbjct: 234 NLFDMCGISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPP 293

Query: 301 VVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPA-----CPSAPAPRR 355
              +G     +   G P P P     AAPP   PP  PS A+PPP       P  PA   
Sbjct: 294 PHNSGPPPPPARGRGAPPPPPSRAPTAAPPPP-PPSRPSVAVPPPPPNRMYPPPPPALPS 352

Query: 356 SIISRPPP 363
           S  S PPP
Sbjct: 353 SAPSGPPP 360


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 28/77 (36%), Positives = 35/77 (45%), Gaps = 9/77 (11%)

Query: 293 PSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSE------ALPPPA 346
           PSP  Q+P  P  +      SP    P+   P  AAPP  VPP PP+       A PPP 
Sbjct: 444 PSPPVQAPFSPPASPPV---SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500

Query: 347 CPSAPAPRRSIISRPPP 363
            P   A     +++PPP
Sbjct: 501 APPPLAAPPLQLAKPPP 517



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 34/109 (31%), Positives = 47/109 (43%), Gaps = 23/109 (21%)

Query: 272 LEMMEARSRGHASPLAANGQSPSPGS---------QSPVVPAGAVSTGSSSPGTPQPAPQ 322
           L  ++A     ASP  +   +PSP +         Q+P  P    S    +P +P  +P 
Sbjct: 402 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP--SPPVQAPFSPPASPP 459

Query: 323 LPLNAAPPSSVPP--------VPPSEALPPPACPSAPAPRRSIISRPPP 363
           +  +A PPS  PP        VPPS    PP  PSA  P ++    PPP
Sbjct: 460 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA----PPP 504



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 29/83 (34%), Positives = 35/83 (42%), Gaps = 4/83 (4%)

Query: 284 SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPV--PPSE- 340
           SP A+   SPS    S   P+ A       P  P   P  P    PP + PP+  PP + 
Sbjct: 453 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512

Query: 341 ALPPPACPSAPA-PRRSIISRPP 362
           A PPP  P A A P    +  PP
Sbjct: 513 AKPPPQAPPALATPPLQALPSPP 535



 Score = 36.6 bits (83), Expect = 0.057
 Identities = 36/98 (36%), Positives = 46/98 (46%), Gaps = 21/98 (21%)

Query: 283 ASPLAANGQSPSPGSQS-PVVPAGAVSTGSSSPGTPQPAPQLPL----NAAPPS-----S 332
           +SPLA    S +  SQ+ P +PA    T  SS  T Q A  LPL     +APPS     S
Sbjct: 301 SSPLATPSPSAALQSQAPPTLPA----TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS 356

Query: 333 VPPVPPSEALPPPACPS-------APAPRRSIISRPPP 363
            P  PPS+A      P+        P+P  S ++ PPP
Sbjct: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 394



 Score = 36.2 bits (82), Expect = 0.075
 Identities = 34/106 (32%), Positives = 42/106 (39%), Gaps = 27/106 (25%)

Query: 285 PLAANGQSPSPGSQS-PVVPAGAVSTGSSSPGTPQ--------PAPQLPLNAAPPSSVPP 335
           PLA    S  P  Q+ P  PA   S  ++S G+P         P+P L   A PP   PP
Sbjct: 339 PLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP 398

Query: 336 ---VPPSEALPPP---------ACPSAPAPRRSIIS------RPPP 363
              +PP +A P P         A PS  AP    +        PPP
Sbjct: 399 ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 444



 Score = 35.8 bits (81), Expect = 0.097
 Identities = 28/76 (36%), Positives = 35/76 (46%), Gaps = 7/76 (9%)

Query: 285 PLAANGQSPS--PGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPP-SEA 341
           PL A    P+  PG Q+P  P+ ++     +   PQ  P L   AAP   VPP PP S  
Sbjct: 527 PLQALPSPPASFPG-QAPFSPSASLPMSPLATPPPQAPPVL---AAPLLQVPPSPPASPT 582

Query: 342 LPPPACPSAPAPRRSI 357
           L  P  P  P P  S+
Sbjct: 583 LQAPRRPPTPGPDTSV 598



 Score = 34.3 bits (77), Expect = 0.28
 Identities = 33/91 (36%), Positives = 39/91 (42%), Gaps = 26/91 (28%)

Query: 285 PLAANG-QSPSPGSQSPVVPAGAVSTGSSSPGTP---------QPAPQLPLN--AAPPSS 332
           PLAA   Q   P  Q+P  PA A     + P  P          P+  LP++  A PP  
Sbjct: 504 PLAAPPLQLAKPPPQAP--PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 561

Query: 333 VPP--------VPPSEALPPPACPSAPAPRR 355
            PP        VPPS    PPA P+  APRR
Sbjct: 562 APPVLAAPLLQVPPS----PPASPTLQAPRR 588



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 30/95 (31%), Positives = 37/95 (38%), Gaps = 16/95 (16%)

Query: 284 SPLAANGQSPS---PGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNA--APPSSVP---P 335
           SP A+   SPS   P    P + A  +      P  P      PL A  +PP+S P   P
Sbjct: 484 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543

Query: 336 VPPSEALP--------PPACPSAPAPRRSIISRPP 362
             PS +LP        P A P   AP   +   PP
Sbjct: 544 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 578



 Score = 30.8 bits (68), Expect = 3.1
 Identities = 27/96 (28%), Positives = 32/96 (33%), Gaps = 7/96 (7%)

Query: 288 ANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPAC 347
           A G  P P        +G    G SS  T  P      ++ P       PP +A      
Sbjct: 608 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 667

Query: 348 PSAPAPRRSIISRPPPWGWRLRGALGRRGQWPPWGG 383
           P+A        SR P      RGA G    WPP  G
Sbjct: 668 PAA-------WSRGPAPPLAFRGAPGAPLPWPPATG 696



 Score = 30.4 bits (67), Expect = 4.1
 Identities = 22/77 (28%), Positives = 29/77 (37%), Gaps = 3/77 (3%)

Query: 283 ASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEAL 342
           A    A G++     +S +       T   +PGTP PA      AA      P P   A 
Sbjct: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 197

Query: 343 PPPACPSAPAPRRSIIS 359
           P    P    PR+S+ S
Sbjct: 198 PR---PPTEGPRKSVSS 211



 Score = 29.6 bits (65), Expect = 7.0
 Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 13/89 (14%)

Query: 287 AANGQSPSPGSQSPVVPAGAVSTGSSSP----------GTPQPAPQLPLNAAPPSSVPPV 336
           +A  + P+ G +  V  A   ST   SP          G  +PA +   ++A P S P  
Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254

Query: 337 --PPSEALP-PPACPSAPAPRRSIISRPP 362
             P +   P  PA PS P P+     RPP
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPP 283


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 28/77 (36%), Positives = 35/77 (45%), Gaps = 9/77 (11%)

Query: 293 PSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSE------ALPPPA 346
           PSP  Q+P  P  +      SP    P+   P  AAPP  VPP PP+       A PPP 
Sbjct: 405 PSPPVQAPFSPPASPPV---SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461

Query: 347 CPSAPAPRRSIISRPPP 363
            P   A     +++PPP
Sbjct: 462 APPPLAAPPLQLAKPPP 478



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 34/109 (31%), Positives = 47/109 (43%), Gaps = 23/109 (21%)

Query: 272 LEMMEARSRGHASPLAANGQSPSPGS---------QSPVVPAGAVSTGSSSPGTPQPAPQ 322
           L  ++A     ASP  +   +PSP +         Q+P  P    S    +P +P  +P 
Sbjct: 363 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP--SPPVQAPFSPPASPP 420

Query: 323 LPLNAAPPSSVPP--------VPPSEALPPPACPSAPAPRRSIISRPPP 363
           +  +A PPS  PP        VPPS    PP  PSA  P ++    PPP
Sbjct: 421 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA----PPP 465



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 29/83 (34%), Positives = 35/83 (42%), Gaps = 4/83 (4%)

Query: 284 SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPV--PPSE- 340
           SP A+   SPS    S   P+ A       P  P   P  P    PP + PP+  PP + 
Sbjct: 414 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 473

Query: 341 ALPPPACPSAPA-PRRSIISRPP 362
           A PPP  P A A P    +  PP
Sbjct: 474 AKPPPQAPPALATPPLQALPSPP 496



 Score = 35.8 bits (81), Expect = 0.097
 Identities = 28/76 (36%), Positives = 35/76 (46%), Gaps = 7/76 (9%)

Query: 285 PLAANGQSPS--PGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPP-SEA 341
           PL A    P+  PG Q+P  P+ ++     +   PQ  P L   AAP   VPP PP S  
Sbjct: 488 PLQALPSPPASFPG-QAPFSPSASLPMSPLATPPPQAPPVL---AAPLLQVPPSPPASPT 543

Query: 342 LPPPACPSAPAPRRSI 357
           L  P  P  P P  S+
Sbjct: 544 LQAPRRPPTPGPDTSV 559



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 34/107 (31%), Positives = 42/107 (39%), Gaps = 27/107 (25%)

Query: 284 SPLAANGQSPSPGSQS-PVVPAGAVSTGSSSPGTPQ--------PAPQLPLNAAPPSSVP 334
           SP A    S  P  Q+ P  PA   S  ++S G+P         P+P L   A PP   P
Sbjct: 299 SPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 358

Query: 335 P---VPPSEALPPP---------ACPSAPAPRRSIIS------RPPP 363
           P   +PP +A P P         A PS  AP    +        PPP
Sbjct: 359 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 405



 Score = 34.3 bits (77), Expect = 0.28
 Identities = 33/91 (36%), Positives = 39/91 (42%), Gaps = 26/91 (28%)

Query: 285 PLAANG-QSPSPGSQSPVVPAGAVSTGSSSPGTP---------QPAPQLPLN--AAPPSS 332
           PLAA   Q   P  Q+P  PA A     + P  P          P+  LP++  A PP  
Sbjct: 465 PLAAPPLQLAKPPPQAP--PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 522

Query: 333 VPP--------VPPSEALPPPACPSAPAPRR 355
            PP        VPPS    PPA P+  APRR
Sbjct: 523 APPVLAAPLLQVPPS----PPASPTLQAPRR 549



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 30/95 (31%), Positives = 37/95 (38%), Gaps = 16/95 (16%)

Query: 284 SPLAANGQSPS---PGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNA--APPSSVP---P 335
           SP A+   SPS   P    P + A  +      P  P      PL A  +PP+S P   P
Sbjct: 445 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 504

Query: 336 VPPSEALP--------PPACPSAPAPRRSIISRPP 362
             PS +LP        P A P   AP   +   PP
Sbjct: 505 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 539



 Score = 30.8 bits (68), Expect = 3.1
 Identities = 27/96 (28%), Positives = 32/96 (33%), Gaps = 7/96 (7%)

Query: 288 ANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPAC 347
           A G  P P        +G    G SS  T  P      ++ P       PP +A      
Sbjct: 569 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 628

Query: 348 PSAPAPRRSIISRPPPWGWRLRGALGRRGQWPPWGG 383
           P+A        SR P      RGA G    WPP  G
Sbjct: 629 PAA-------WSRGPAPPLAFRGAPGAPLPWPPATG 657



 Score = 30.4 bits (67), Expect = 4.1
 Identities = 22/77 (28%), Positives = 29/77 (37%), Gaps = 3/77 (3%)

Query: 283 ASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEAL 342
           A    A G++     +S +       T   +PGTP PA      AA      P P   A 
Sbjct: 129 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 188

Query: 343 PPPACPSAPAPRRSIIS 359
           P    P    PR+S+ S
Sbjct: 189 PR---PPTEGPRKSVSS 202



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 3/70 (4%)

Query: 287 AANGQSPSPGSQSPVVPAG--AVSTGSSSPGTPQPAPQL-PLNAAPPSSVPPVPPSEALP 343
           +A G   +P   S   P G  A+     +P     AP L PL+++P ++  P  P     
Sbjct: 249 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA 308

Query: 344 PPACPSAPAP 353
           PP+  + P+P
Sbjct: 309 PPSLQTLPSP 318



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 17/102 (16%)

Query: 278 RSRGHASPLAANG-QSPSPGSQSPVVPAGAVSTG--SSSPGTPQPAPQLPLNAAPPSSVP 334
           R+  H S     G Q+  P   +P     A + G  SSSP    P+P  P + + P S+ 
Sbjct: 255 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP-LATPSPSAPPSPSAPPSLQ 313

Query: 335 PVPPSEALPPPACPSA-------------PAPRRSIISRPPP 363
            +P   A PP    ++             P+P  S ++ PPP
Sbjct: 314 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 355


>gi|4758996 Ras-related protein Rab-33A [Homo sapiens]
          Length = 237

 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 44/169 (26%), Positives = 72/169 (42%), Gaps = 37/169 (21%)

Query: 23  AGLQSMNQALQRRFAKGVQYNM-KIVIRGDRNTGKTALWHRLQGRPFVEEYIPTQEIQVT 81
           AGL S+   L     + VQ  + KI++ GD N GKT L  R  G  F     P +     
Sbjct: 17  AGLASLE--LDSSLDQYVQIRIFKIIVIGDSNVGKTCLTFRFCGGTF-----PDKTEATI 69

Query: 82  SIHWSYKTTD---DIVKVEVWDVVDKGKCKKRGDGLKMENDPQEAESEMALDAEFLDVYK 138
            + +  KT +   + +KV+VWD   + + +K                     +     Y+
Sbjct: 70  GVDFREKTVEIEGEKIKVQVWDTAGQERFRK---------------------SMVEHYYR 108

Query: 139 NCNGVVMMFDITKQWTFNYILRELPK-----VPTHVPVCVLGNYRDMGE 182
           N + VV ++D+TK  +F  +   + +     VP  VP  ++GN  D+ E
Sbjct: 109 NVHAVVFVYDVTKMTSFTNLKMWIQECNGHAVPPLVPKVLVGNKCDLRE 157


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 37/109 (33%), Positives = 42/109 (38%), Gaps = 24/109 (22%)

Query: 281 GHASPLAANGQSPSPGSQSPV------------VPAGAVSTGSSSPGTPQP--APQLPLN 326
           G  SP  A    P+PG+  P              P  A       PG+P+P  AP LP +
Sbjct: 524 GSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGD 583

Query: 327 AAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRPPPWGWRLRGALGRR 375
             PP   PP PP    P P  P  P         PPP G     ALGRR
Sbjct: 584 LPPPPPPPPPPPGTDGPVPPPPPPPP--------PPPGG--PPDALGRR 622



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 29/81 (35%), Positives = 37/81 (45%), Gaps = 7/81 (8%)

Query: 288 ANGQSPSPG----SQSPVVPAGAVSTGSSSPGTPQPAPQLPL-NAAPPSSVPPVPPSEAL 342
           + G +P+PG    S SP +   A     ++P  P P P LP    APPS+ P  PP    
Sbjct: 512 SGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGS 571

Query: 343 PPPACPSAPAPRRSIISRPPP 363
           P P  P AP     +   PPP
Sbjct: 572 PEP--PPAPPLPGDLPPPPPP 590



 Score = 36.6 bits (83), Expect = 0.057
 Identities = 29/72 (40%), Positives = 34/72 (47%), Gaps = 8/72 (11%)

Query: 300 PVVPAGAVSTGSSSPGTP--QPAPQLPLNA--APPSSVPPVPPSEALPPP--ACPSAP-- 351
           PV  A      + +PG P   P+P L   A  AP ++ PP PP   LP P  A PSAP  
Sbjct: 505 PVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQ 564

Query: 352 APRRSIISRPPP 363
           AP       PPP
Sbjct: 565 APPLPGSPEPPP 576



 Score = 29.3 bits (64), Expect = 9.1
 Identities = 41/187 (21%), Positives = 61/187 (32%), Gaps = 46/187 (24%)

Query: 222 YLHKFFNIPFLQLQRET---LLRQLETNQLDM--------DATLEELSVQQETEDQNYGI 270
           YL   F++  L    ET   +L  +E  Q  +        DA  E ++   E E Q    
Sbjct: 377 YLDNIFDVGALLEDTETKNAVLEHMEELQEQVALLTERLRDAENESMAKIAELEKQLSQA 436

Query: 271 FLEMMEARSR-GHASPLAANGQSPSPGSQSPVVPAGAVSTGSS--------------SPG 315
             E+   R R   ++ + A+ + P P    P  P    +                   PG
Sbjct: 437 RKELETLRERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPG 496

Query: 316 TPQPAPQLPLNAAPPS--------------------SVPPVPPSEALPPPACPSAPAPRR 355
                  LP+  A PS                    +  P P +   PPP  P  P+P+ 
Sbjct: 497 DAVSIEILPVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQE 556

Query: 356 SIISRPP 362
           +  S PP
Sbjct: 557 APPSAPP 563


>gi|7661922 RAB21, member RAS oncogene family [Homo sapiens]
          Length = 225

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 47/217 (21%), Positives = 96/217 (44%), Gaps = 46/217 (21%)

Query: 37  AKGVQYNMKIVIRGDRNTGKTALWHRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKV 96
           A G  Y+ K+V+ G+   GKT+L  R     F +++I T  +Q + +          V +
Sbjct: 13  AAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITT--LQASFLTKKLNIGGKRVNL 70

Query: 97  EVWDVVDKGKCKKRGDGLKMENDPQEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFN 156
            +WD   + +    G                         Y++ NG ++++DIT + +F 
Sbjct: 71  AIWDTAGQERFHALGP----------------------IYYRDSNGAILVYDITDEDSFQ 108

Query: 157 YI---LRELPK-VPTHVPVCVLGNYRDMGEHRVILPDDVRDFIDNLDRPPGSSYFRYAES 212
            +   ++EL K +   + +C++GN  D+ + R +   +   + +++    G+ ++    +
Sbjct: 109 KVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESV----GAKHY---HT 161

Query: 213 SMKNSFGLKYLHKFFNIPFLQLQRETLLRQLETNQLD 249
           S K + G++ L       FL L +    R +ET Q+D
Sbjct: 162 SAKQNKGIEEL-------FLDLCK----RMIETAQVD 187


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 7/76 (9%)

Query: 288 ANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPAC 347
           A+ QSP P   +P   A AV+  +++  T            PP ++PP PP    PPP+ 
Sbjct: 730 ASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQ 789

Query: 348 PSAPAPRRSIISRPPP 363
           P  P P       PPP
Sbjct: 790 PQPPPP-------PPP 798



 Score = 37.0 bits (84), Expect = 0.044
 Identities = 33/104 (31%), Positives = 41/104 (39%), Gaps = 22/104 (21%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSS------PGTPQPAPQLPLNAAPPSSVPPVPP 338
           P A +G    P  +  + P G    G +S      PG P P P LP    PP   PP PP
Sbjct: 211 PAALSG----PSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLP---PPP---PPPPP 260

Query: 339 SEALPPPACPSAPAPRRSIISRPPPWGWRLRGALG--RRGQWPP 380
               PPP  P         +++P  W      A G  R+G  PP
Sbjct: 261 ----PPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP 300



 Score = 33.1 bits (74), Expect = 0.63
 Identities = 31/95 (32%), Positives = 38/95 (40%), Gaps = 17/95 (17%)

Query: 279 SRGHASPLAANGQSPSPG---SQSPVVPAGAVS----TGSSSPGTPQPAPQLPLNAAPPS 331
           S   +S     G  P+PG   +     PA  VS     G S+  + +P    P  A P  
Sbjct: 401 SSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPA-ATPHL 459

Query: 332 SVPPVPPSEALPPPACPSAPAPRRSIISRPPPWGW 366
           S+PP P S   PPP CP    P       PPP  W
Sbjct: 460 SLPPGPSSP--PPPPCPRLLRP-------PPPPAW 485



 Score = 30.8 bits (68), Expect = 3.1
 Identities = 18/54 (33%), Positives = 21/54 (38%), Gaps = 1/54 (1%)

Query: 283 ASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGT-PQPAPQLPLNAAPPSSVPP 335
           A+P A     PS  S S    +G         G  P P P  P    PP S+PP
Sbjct: 853 AAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPP 906



 Score = 30.4 bits (67), Expect = 4.1
 Identities = 16/52 (30%), Positives = 24/52 (46%), Gaps = 2/52 (3%)

Query: 309 TGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISR 360
           TG++    P P P    +  PPS    +PP+ A   P+   +P P  S  S+
Sbjct: 821 TGAAVSTRPGPLPTTQYSPGPPSGATALPPTSA--APSAQGSPQPSASSSSQ 870



 Score = 30.4 bits (67), Expect = 4.1
 Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 12/70 (17%)

Query: 310  GSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALP----------PPACPSAPAPRRSIIS 359
            G +S   P  AP  P  +AP  S  P PPS ++P          PP    A   +   +S
Sbjct: 1039 GGASKAKPPTAPAPP--SAPAPSAQPTPPSASVPGKKAREEAPGPPGVSRADMLKLRSLS 1096

Query: 360  RPPPWGWRLR 369
              PP   ++R
Sbjct: 1097 EGPPKELKIR 1106



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 11/76 (14%)

Query: 275 MEARSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVP 334
           +E    G   P A + + P  G+ +   P  ++  G SSP  P P P+L         + 
Sbjct: 430 LEVSHHGRLGPSAHSSRKPFLGAPA-ATPHLSLPPGPSSP-PPPPCPRL---------LR 478

Query: 335 PVPPSEALPPPACPSA 350
           P PP   L  PAC +A
Sbjct: 479 PPPPPAWLKGPACRAA 494


>gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]
          Length = 1096

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 39/130 (30%), Positives = 54/130 (41%), Gaps = 17/130 (13%)

Query: 255 EELSVQQET--EDQNYGIFLEMMEA---RSRGHASPLAANGQSPSPGSQSPVVPAGAVST 309
           EE + +QE   E Q     ++ +EA   + R  A  L+++   P P +  P+   G    
Sbjct: 506 EEFTARQEAQAELQKRDEKIKELEAEIQQLRTQAQVLSSSSGIPGPPAAPPLPGVG---- 561

Query: 310 GSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACP----SAPAPRRSIISRPPPWG 365
               P  P PAP LP  A  P   PP+P    +PPP  P      P P   +   PPP G
Sbjct: 562 ----PPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLLFGGPPPPPPLGGVPPPPG 617

Query: 366 WRLRGALGRR 375
             L    G +
Sbjct: 618 ISLNLPYGMK 627


>gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]
          Length = 1101

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 39/130 (30%), Positives = 54/130 (41%), Gaps = 17/130 (13%)

Query: 255 EELSVQQET--EDQNYGIFLEMMEA---RSRGHASPLAANGQSPSPGSQSPVVPAGAVST 309
           EE + +QE   E Q     ++ +EA   + R  A  L+++   P P +  P+   G    
Sbjct: 506 EEFTARQEAQAELQKRDEKIKELEAEIQQLRTQAQVLSSSSGIPGPPAAPPLPGVG---- 561

Query: 310 GSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACP----SAPAPRRSIISRPPPWG 365
               P  P PAP LP  A  P   PP+P    +PPP  P      P P   +   PPP G
Sbjct: 562 ----PPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLLFGGPPPPPPLGGVPPPPG 617

Query: 366 WRLRGALGRR 375
             L    G +
Sbjct: 618 ISLNLPYGMK 627


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 6/90 (6%)

Query: 274  MMEARSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSV 333
            + +A+S     PLA+   +P P S S  VPA   ST +  P T  P P       P S++
Sbjct: 1737 IQQAQSSASVPPLAS---APLPPSTSASVPA---STSAPLPATLTPVPASTSAPVPASTL 1790

Query: 334  PPVPPSEALPPPACPSAPAPRRSIISRPPP 363
             PV  S + P PA P AP    + +S   P
Sbjct: 1791 APVLASTSAPVPASPLAPVSASASVSASVP 1820



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 8/86 (9%)

Query: 284  SPLAANGQSPSPGS--QSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVP---P 338
            +P+ A+  +P+  +   S  +P  A +  S+S  TP PA   P  AAP  + P +P   P
Sbjct: 1841 TPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSP--AAPVITAPTIPASAP 1898

Query: 339  SEALP-PPACPSAPAPRRSIISRPPP 363
            + ++P  PA  SAPAP  + +S P P
Sbjct: 1899 TASVPLAPASASAPAPAPTPVSAPNP 1924



 Score = 36.6 bits (83), Expect = 0.057
 Identities = 27/80 (33%), Positives = 40/80 (50%), Gaps = 6/80 (7%)

Query: 283  ASPLAA-NGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEA 341
            AS LA+ +  +P+P + SP  P   V T  + P +  P   +PL  A  S+  P P   +
Sbjct: 1865 ASALASTSAPTPAPAASSPAAP---VITAPTIPASA-PTASVPLAPASASAPAPAPTPVS 1920

Query: 342  LPPPACPSAPAPRRSIISRP 361
             P PA P APA  ++   +P
Sbjct: 1921 APNPA-PPAPAQTQAQTHKP 1939



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 283  ASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPA-PQLPLNAAP--PSSVPPVPPS 339
            ++PL A   +P P S S  VPA  ++   +S   P PA P  P++A+    +SVP    +
Sbjct: 1767 SAPLPAT-LTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSA 1825

Query: 340  EALPPPACP-SAPAPRRSIISRPPP 363
             A+   + P SAPAP   + S   P
Sbjct: 1826 AAITSSSAPASAPAPTPILASVSTP 1850



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 26/124 (20%), Positives = 45/124 (36%), Gaps = 10/124 (8%)

Query: 232 LQLQRETLLRQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQ 291
           L+ +RE L  ++E  + +++  +E+   +     +   +F      RS   A+P+    +
Sbjct: 589 LEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETE 648

Query: 292 SPSPGSQSPVVPAGAVSTGSSS----------PGTPQPAPQLPLNAAPPSSVPPVPPSEA 341
             S     P V +G       S              Q   Q       P +VP  P S  
Sbjct: 649 PESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSST 708

Query: 342 LPPP 345
           +PPP
Sbjct: 709 VPPP 712



 Score = 30.4 bits (67), Expect = 4.1
 Identities = 18/63 (28%), Positives = 32/63 (50%), Gaps = 2/63 (3%)

Query: 284  SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALP 343
            +P+ A+  +P P S  P+ P  A ++ S+S      A  +  ++AP S+  P P   ++ 
Sbjct: 1791 APVLASTSAPVPAS--PLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVS 1848

Query: 344  PPA 346
             PA
Sbjct: 1849 TPA 1851



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 7/77 (9%)

Query: 288  ANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVP-------PSE 340
            AN +  S  S+ P   A   +TG     +    P L     PPS+   VP       P+ 
Sbjct: 1714 ANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPAT 1773

Query: 341  ALPPPACPSAPAPRRSI 357
              P PA  SAP P  ++
Sbjct: 1774 LTPVPASTSAPVPASTL 1790


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 5/77 (6%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP 344
           P     + P+P   +P    G  ST S      +PAP  P   AP +   P P +   P 
Sbjct: 655 PAPTTPKKPAPKELAPTTTKGPTSTTSD-----KPAPTTPKETAPTTPKEPAPTTPKKPA 709

Query: 345 PACPSAPAPRRSIISRP 361
           P  P  P P  S +S P
Sbjct: 710 PTTPETPPPTTSEVSTP 726



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 5/70 (7%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVPPSEALP 343
           P     + P+P +     P    +T  S+P TP +PAP  P   AP +   P P +   P
Sbjct: 270 PAPTTPKEPAPTTTKEPAP----TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 325

Query: 344 PPACPSAPAP 353
            P  P  PAP
Sbjct: 326 TPTTPKEPAP 335



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 2/62 (3%)

Query: 294 SPGSQSPVVPAGAVSTGSSSPG--TPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAP 351
           +P   +P  P     T    P   T +PAP  P   AP +   P P +   P P  P  P
Sbjct: 313 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 372

Query: 352 AP 353
           AP
Sbjct: 373 AP 374



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 12/90 (13%)

Query: 284 SPLAANGQSPSPGSQSPVVPAG-AVSTGSSSPGTP---------QPAPQLPLNAAPPSSV 333
           SP      +P+    +P      A +T  S+P TP         +PAP  P   AP +  
Sbjct: 381 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 440

Query: 334 PPVPPSEALPPPACPSAPAPRRSIISRPPP 363
            P P +   P P  P  PAP  +   +P P
Sbjct: 441 KPAPTTPKEPAPTTPKEPAP--TTTKKPAP 468



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%)

Query: 291 QSPSPGSQSPVVPAGAVSTGSSSPGTPQ-PAPQLPLNAAPPSSVPPVPPSEALPPPACPS 349
           + P+P +   + P    +    +P TP+ PAP  P  AAP +   P P +   P P  P 
Sbjct: 504 EKPAPTTPEELAPT---TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 560

Query: 350 APAP 353
            PAP
Sbjct: 561 EPAP 564



 Score = 36.2 bits (82), Expect = 0.075
 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 3/69 (4%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP 344
           P     + P+P ++ P  P        ++P   +PAP  P   AP +   P P +   P 
Sbjct: 325 PTPTTPKEPAPTTKEPA-PTTPKEPAPTAP--KKPAPTTPKEPAPTTPKEPAPTTTKEPS 381

Query: 345 PACPSAPAP 353
           P  P  PAP
Sbjct: 382 PTTPKEPAP 390



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 4/73 (5%)

Query: 284 SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPG--TP-QPAPQLPLNAAPPSSVPPVPPSE 340
           +P      +P+    +P  P     T    P   TP +PAP  P    P +   P P ++
Sbjct: 279 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 338

Query: 341 ALPPPACPSAPAP 353
             P P  P  PAP
Sbjct: 339 E-PAPTTPKEPAP 350



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 6/76 (7%)

Query: 283 ASPLAANGQSPS----PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVP 337
           ++P      SP+    P   +P  PA   +    +P TP +PAP  P   AP ++  P P
Sbjct: 410 SAPTTPKEPSPTTTKEPAPTTPKEPA-PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 468

Query: 338 PSEALPPPACPSAPAP 353
            +   P P  P   AP
Sbjct: 469 TTPKEPAPTTPKETAP 484



 Score = 34.3 bits (77), Expect = 0.28
 Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 2/59 (3%)

Query: 295 PGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAP 353
           P S +P  P    +T  S+P TP+        +AP +   P P +   P P  P  PAP
Sbjct: 224 PASTTPKEPTP--TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 280



 Score = 34.3 bits (77), Expect = 0.28
 Identities = 19/76 (25%), Positives = 28/76 (36%), Gaps = 6/76 (7%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP------QPAPQLPLNAAPPSSVPPVPP 338
           P     + P+P +     P        ++P  P      +PAP  P   AP +     P 
Sbjct: 522 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT 581

Query: 339 SEALPPPACPSAPAPR 354
           +   P P  P  PAP+
Sbjct: 582 TLKEPAPTTPKKPAPK 597



 Score = 33.9 bits (76), Expect = 0.37
 Identities = 22/81 (27%), Positives = 31/81 (38%), Gaps = 11/81 (13%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTG----------SSSPGTP-QPAPQLPLNAAPPSSV 333
           P     + P+P   +P       ST            ++P TP +PAP  P   AP +  
Sbjct: 586 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 645

Query: 334 PPVPPSEALPPPACPSAPAPR 354
              P +   P P  P  PAP+
Sbjct: 646 GTAPTTLKEPAPTTPKKPAPK 666



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 23/90 (25%)

Query: 285 PLAANGQSPSPGS--QSPVVPAG-AVSTGSSSPGTP---------QPAPQLPLNAAPPSS 332
           P +   + P+P +   +P  P   A +T  S+P TP         +PAP  P   AP ++
Sbjct: 224 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 283

Query: 333 VPPVP---------PSEALPPPACPSAPAP 353
             P P         P E  P P  P  PAP
Sbjct: 284 KEPAPTTTKSAPTTPKE--PAPTTPKKPAP 311



 Score = 32.7 bits (73), Expect = 0.82
 Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 6/62 (9%)

Query: 295 PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAP--PSSVPPVPPSEALPPPACPSAP 351
           P   +P  PA   +T   +P TP +PAP  P   AP  P  + P  P +    P  P  P
Sbjct: 450 PAPTTPKEPA-PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL--APTTPEKP 506

Query: 352 AP 353
           AP
Sbjct: 507 AP 508



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 7/65 (10%)

Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQ-PAPQLPLNAAP--PSSVPPVPPSEALPPPACP 348
           +P   +P  P     T     +P TP+ PAP  P   AP  P    P  P E  P P  P
Sbjct: 478 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE--PAPTTP 535

Query: 349 SAPAP 353
            A AP
Sbjct: 536 KAAAP 540



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 22/65 (33%), Positives = 27/65 (41%), Gaps = 7/65 (10%)

Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQP-APQLPLNAAP--PSSVPPVPPSEALPPPACP 348
           +P   +P  P     T     +P TP+  AP  P   AP  P  + P  P E  P P  P
Sbjct: 470 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE--PTPTTP 527

Query: 349 SAPAP 353
             PAP
Sbjct: 528 EEPAP 532



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 19/63 (30%), Positives = 25/63 (39%), Gaps = 3/63 (4%)

Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQ-PAPQLPLNAAPPSSVPPVPPSEALPPPACPSA 350
           +P   +P  P     T     +P TP+ P P  P   AP +     P +   P P  P  
Sbjct: 494 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 553

Query: 351 PAP 353
           PAP
Sbjct: 554 PAP 556



 Score = 29.6 bits (65), Expect = 7.0
 Identities = 26/89 (29%), Positives = 35/89 (39%), Gaps = 20/89 (22%)

Query: 284 SPLAANGQSPS----PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNA----------- 327
           +P A    +P+    P   +P  PA   +T   SP TP +PAP    +A           
Sbjct: 349 APTAPKKPAPTTPKEPAPTTPKEPA-PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT 407

Query: 328 ---APPSSVPPVPPSEALPPPACPSAPAP 353
              AP +   P P +   P P  P  PAP
Sbjct: 408 TKSAPTTPKEPSPTTTKEPAPTTPKEPAP 436



 Score = 29.3 bits (64), Expect = 9.1
 Identities = 19/68 (27%), Positives = 23/68 (33%), Gaps = 8/68 (11%)

Query: 294 SPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAP-----PSSVP---PVPPSEALPPP 345
           +P   +P  P G   T    P    P    P   AP     P+S     P P +     P
Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 625

Query: 346 ACPSAPAP 353
             P  PAP
Sbjct: 626 TTPKEPAP 633


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 5/77 (6%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP 344
           P     + P+P   +P    G  ST S      +PAP  P   AP +   P P +   P 
Sbjct: 696 PAPTTPKKPAPKELAPTTTKGPTSTTSD-----KPAPTTPKETAPTTPKEPAPTTPKKPA 750

Query: 345 PACPSAPAPRRSIISRP 361
           P  P  P P  S +S P
Sbjct: 751 PTTPETPPPTTSEVSTP 767



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 5/70 (7%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVPPSEALP 343
           P     + P+P +     P    +T  S+P TP +PAP  P   AP +   P P +   P
Sbjct: 311 PAPTTPKEPAPTTTKEPAP----TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 366

Query: 344 PPACPSAPAP 353
            P  P  PAP
Sbjct: 367 TPTTPKEPAP 376



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 2/62 (3%)

Query: 294 SPGSQSPVVPAGAVSTGSSSPG--TPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAP 351
           +P   +P  P     T    P   T +PAP  P   AP +   P P +   P P  P  P
Sbjct: 354 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 413

Query: 352 AP 353
           AP
Sbjct: 414 AP 415



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 12/90 (13%)

Query: 284 SPLAANGQSPSPGSQSPVVPAG-AVSTGSSSPGTP---------QPAPQLPLNAAPPSSV 333
           SP      +P+    +P      A +T  S+P TP         +PAP  P   AP +  
Sbjct: 422 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 481

Query: 334 PPVPPSEALPPPACPSAPAPRRSIISRPPP 363
            P P +   P P  P  PAP  +   +P P
Sbjct: 482 KPAPTTPKEPAPTTPKEPAP--TTTKKPAP 509



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%)

Query: 291 QSPSPGSQSPVVPAGAVSTGSSSPGTPQ-PAPQLPLNAAPPSSVPPVPPSEALPPPACPS 349
           + P+P +   + P    +    +P TP+ PAP  P  AAP +   P P +   P P  P 
Sbjct: 545 EKPAPTTPEELAPT---TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 601

Query: 350 APAP 353
            PAP
Sbjct: 602 EPAP 605



 Score = 36.2 bits (82), Expect = 0.075
 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 3/69 (4%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP 344
           P     + P+P ++ P  P        ++P   +PAP  P   AP +   P P +   P 
Sbjct: 366 PTPTTPKEPAPTTKEPA-PTTPKEPAPTAP--KKPAPTTPKEPAPTTPKEPAPTTTKEPS 422

Query: 345 PACPSAPAP 353
           P  P  PAP
Sbjct: 423 PTTPKEPAP 431



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 4/73 (5%)

Query: 284 SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPG--TP-QPAPQLPLNAAPPSSVPPVPPSE 340
           +P      +P+    +P  P     T    P   TP +PAP  P    P +   P P ++
Sbjct: 320 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 379

Query: 341 ALPPPACPSAPAP 353
             P P  P  PAP
Sbjct: 380 E-PAPTTPKEPAP 391



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 6/76 (7%)

Query: 283 ASPLAANGQSPS----PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVP 337
           ++P      SP+    P   +P  PA   +    +P TP +PAP  P   AP ++  P P
Sbjct: 451 SAPTTPKEPSPTTTKEPAPTTPKEPA-PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 509

Query: 338 PSEALPPPACPSAPAP 353
            +   P P  P   AP
Sbjct: 510 TTPKEPAPTTPKETAP 525



 Score = 34.3 bits (77), Expect = 0.28
 Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 2/59 (3%)

Query: 295 PGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAP 353
           P S +P  P    +T  S+P TP+        +AP +   P P +   P P  P  PAP
Sbjct: 265 PASTTPKEPTP--TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 321



 Score = 34.3 bits (77), Expect = 0.28
 Identities = 19/76 (25%), Positives = 28/76 (36%), Gaps = 6/76 (7%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP------QPAPQLPLNAAPPSSVPPVPP 338
           P     + P+P +     P        ++P  P      +PAP  P   AP +     P 
Sbjct: 563 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT 622

Query: 339 SEALPPPACPSAPAPR 354
           +   P P  P  PAP+
Sbjct: 623 TLKEPAPTTPKKPAPK 638



 Score = 33.9 bits (76), Expect = 0.37
 Identities = 22/81 (27%), Positives = 31/81 (38%), Gaps = 11/81 (13%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTG----------SSSPGTP-QPAPQLPLNAAPPSSV 333
           P     + P+P   +P       ST            ++P TP +PAP  P   AP +  
Sbjct: 627 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 686

Query: 334 PPVPPSEALPPPACPSAPAPR 354
              P +   P P  P  PAP+
Sbjct: 687 GTAPTTLKEPAPTTPKKPAPK 707



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 23/90 (25%)

Query: 285 PLAANGQSPSPGS--QSPVVPAG-AVSTGSSSPGTP---------QPAPQLPLNAAPPSS 332
           P +   + P+P +   +P  P   A +T  S+P TP         +PAP  P   AP ++
Sbjct: 265 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 324

Query: 333 VPPVP---------PSEALPPPACPSAPAP 353
             P P         P E  P P  P  PAP
Sbjct: 325 KEPAPTTTKSAPTTPKE--PAPTTPKKPAP 352



 Score = 32.7 bits (73), Expect = 0.82
 Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 6/62 (9%)

Query: 295 PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAP--PSSVPPVPPSEALPPPACPSAP 351
           P   +P  PA   +T   +P TP +PAP  P   AP  P  + P  P +    P  P  P
Sbjct: 491 PAPTTPKEPA-PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL--APTTPEKP 547

Query: 352 AP 353
           AP
Sbjct: 548 AP 549



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 7/65 (10%)

Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQ-PAPQLPLNAAP--PSSVPPVPPSEALPPPACP 348
           +P   +P  P     T     +P TP+ PAP  P   AP  P    P  P E  P P  P
Sbjct: 519 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE--PAPTTP 576

Query: 349 SAPAP 353
            A AP
Sbjct: 577 KAAAP 581



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 22/65 (33%), Positives = 27/65 (41%), Gaps = 7/65 (10%)

Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQP-APQLPLNAAP--PSSVPPVPPSEALPPPACP 348
           +P   +P  P     T     +P TP+  AP  P   AP  P  + P  P E  P P  P
Sbjct: 511 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE--PTPTTP 568

Query: 349 SAPAP 353
             PAP
Sbjct: 569 EEPAP 573



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 19/63 (30%), Positives = 25/63 (39%), Gaps = 3/63 (4%)

Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQ-PAPQLPLNAAPPSSVPPVPPSEALPPPACPSA 350
           +P   +P  P     T     +P TP+ P P  P   AP +     P +   P P  P  
Sbjct: 535 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 594

Query: 351 PAP 353
           PAP
Sbjct: 595 PAP 597



 Score = 29.6 bits (65), Expect = 7.0
 Identities = 26/89 (29%), Positives = 35/89 (39%), Gaps = 20/89 (22%)

Query: 284 SPLAANGQSPS----PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNA----------- 327
           +P A    +P+    P   +P  PA   +T   SP TP +PAP    +A           
Sbjct: 390 APTAPKKPAPTTPKEPAPTTPKEPA-PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT 448

Query: 328 ---APPSSVPPVPPSEALPPPACPSAPAP 353
              AP +   P P +   P P  P  PAP
Sbjct: 449 TKSAPTTPKEPSPTTTKEPAPTTPKEPAP 477



 Score = 29.3 bits (64), Expect = 9.1
 Identities = 19/68 (27%), Positives = 23/68 (33%), Gaps = 8/68 (11%)

Query: 294 SPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAP-----PSSVP---PVPPSEALPPP 345
           +P   +P  P G   T    P    P    P   AP     P+S     P P +     P
Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 666

Query: 346 ACPSAPAP 353
             P  PAP
Sbjct: 667 TTPKEPAP 674


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 5/77 (6%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP 344
           P     + P+P   +P    G  ST S      +PAP  P   AP +   P P +   P 
Sbjct: 748 PAPTTPKKPAPKELAPTTTKGPTSTTSD-----KPAPTTPKETAPTTPKEPAPTTPKKPA 802

Query: 345 PACPSAPAPRRSIISRP 361
           P  P  P P  S +S P
Sbjct: 803 PTTPETPPPTTSEVSTP 819



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 5/70 (7%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVPPSEALP 343
           P     + P+P +     P    +T  S+P TP +PAP  P   AP +   P P +   P
Sbjct: 363 PAPTTPKEPAPTTTKEPAP----TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 418

Query: 344 PPACPSAPAP 353
            P  P  PAP
Sbjct: 419 TPTTPKEPAP 428



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 2/62 (3%)

Query: 294 SPGSQSPVVPAGAVSTGSSSPG--TPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAP 351
           +P   +P  P     T    P   T +PAP  P   AP +   P P +   P P  P  P
Sbjct: 406 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 465

Query: 352 AP 353
           AP
Sbjct: 466 AP 467



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 12/90 (13%)

Query: 284 SPLAANGQSPSPGSQSPVVPAG-AVSTGSSSPGTP---------QPAPQLPLNAAPPSSV 333
           SP      +P+    +P      A +T  S+P TP         +PAP  P   AP +  
Sbjct: 474 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 533

Query: 334 PPVPPSEALPPPACPSAPAPRRSIISRPPP 363
            P P +   P P  P  PAP  +   +P P
Sbjct: 534 KPAPTTPKEPAPTTPKEPAP--TTTKKPAP 561



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%)

Query: 291 QSPSPGSQSPVVPAGAVSTGSSSPGTPQ-PAPQLPLNAAPPSSVPPVPPSEALPPPACPS 349
           + P+P +   + P    +    +P TP+ PAP  P  AAP +   P P +   P P  P 
Sbjct: 597 EKPAPTTPEELAPT---TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 653

Query: 350 APAP 353
            PAP
Sbjct: 654 EPAP 657



 Score = 36.2 bits (82), Expect = 0.075
 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 3/69 (4%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP 344
           P     + P+P ++ P  P        ++P   +PAP  P   AP +   P P +   P 
Sbjct: 418 PTPTTPKEPAPTTKEPA-PTTPKEPAPTAP--KKPAPTTPKEPAPTTPKEPAPTTTKEPS 474

Query: 345 PACPSAPAP 353
           P  P  PAP
Sbjct: 475 PTTPKEPAP 483



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 4/73 (5%)

Query: 284 SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPG--TP-QPAPQLPLNAAPPSSVPPVPPSE 340
           +P      +P+    +P  P     T    P   TP +PAP  P    P +   P P ++
Sbjct: 372 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 431

Query: 341 ALPPPACPSAPAP 353
             P P  P  PAP
Sbjct: 432 E-PAPTTPKEPAP 443



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 6/76 (7%)

Query: 283 ASPLAANGQSPS----PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVP 337
           ++P      SP+    P   +P  PA   +    +P TP +PAP  P   AP ++  P P
Sbjct: 503 SAPTTPKEPSPTTTKEPAPTTPKEPA-PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 561

Query: 338 PSEALPPPACPSAPAP 353
            +   P P  P   AP
Sbjct: 562 TTPKEPAPTTPKETAP 577



 Score = 34.3 bits (77), Expect = 0.28
 Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 2/59 (3%)

Query: 295 PGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAP 353
           P S +P  P    +T  S+P TP+        +AP +   P P +   P P  P  PAP
Sbjct: 317 PASTTPKEPTP--TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 373



 Score = 34.3 bits (77), Expect = 0.28
 Identities = 19/76 (25%), Positives = 28/76 (36%), Gaps = 6/76 (7%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP------QPAPQLPLNAAPPSSVPPVPP 338
           P     + P+P +     P        ++P  P      +PAP  P   AP +     P 
Sbjct: 615 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT 674

Query: 339 SEALPPPACPSAPAPR 354
           +   P P  P  PAP+
Sbjct: 675 TLKEPAPTTPKKPAPK 690



 Score = 33.9 bits (76), Expect = 0.37
 Identities = 22/81 (27%), Positives = 31/81 (38%), Gaps = 11/81 (13%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTG----------SSSPGTP-QPAPQLPLNAAPPSSV 333
           P     + P+P   +P       ST            ++P TP +PAP  P   AP +  
Sbjct: 679 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 738

Query: 334 PPVPPSEALPPPACPSAPAPR 354
              P +   P P  P  PAP+
Sbjct: 739 GTAPTTLKEPAPTTPKKPAPK 759



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 23/90 (25%)

Query: 285 PLAANGQSPSPGS--QSPVVPAG-AVSTGSSSPGTP---------QPAPQLPLNAAPPSS 332
           P +   + P+P +   +P  P   A +T  S+P TP         +PAP  P   AP ++
Sbjct: 317 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 376

Query: 333 VPPVP---------PSEALPPPACPSAPAP 353
             P P         P E  P P  P  PAP
Sbjct: 377 KEPAPTTTKSAPTTPKE--PAPTTPKKPAP 404



 Score = 32.7 bits (73), Expect = 0.82
 Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 6/62 (9%)

Query: 295 PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAP--PSSVPPVPPSEALPPPACPSAP 351
           P   +P  PA   +T   +P TP +PAP  P   AP  P  + P  P +    P  P  P
Sbjct: 543 PAPTTPKEPA-PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL--APTTPEKP 599

Query: 352 AP 353
           AP
Sbjct: 600 AP 601



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 7/65 (10%)

Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQ-PAPQLPLNAAP--PSSVPPVPPSEALPPPACP 348
           +P   +P  P     T     +P TP+ PAP  P   AP  P    P  P E  P P  P
Sbjct: 571 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE--PAPTTP 628

Query: 349 SAPAP 353
            A AP
Sbjct: 629 KAAAP 633



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 22/65 (33%), Positives = 27/65 (41%), Gaps = 7/65 (10%)

Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQP-APQLPLNAAP--PSSVPPVPPSEALPPPACP 348
           +P   +P  P     T     +P TP+  AP  P   AP  P  + P  P E  P P  P
Sbjct: 563 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE--PTPTTP 620

Query: 349 SAPAP 353
             PAP
Sbjct: 621 EEPAP 625



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 19/63 (30%), Positives = 25/63 (39%), Gaps = 3/63 (4%)

Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQ-PAPQLPLNAAPPSSVPPVPPSEALPPPACPSA 350
           +P   +P  P     T     +P TP+ P P  P   AP +     P +   P P  P  
Sbjct: 587 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 646

Query: 351 PAP 353
           PAP
Sbjct: 647 PAP 649



 Score = 29.6 bits (65), Expect = 7.0
 Identities = 26/89 (29%), Positives = 35/89 (39%), Gaps = 20/89 (22%)

Query: 284 SPLAANGQSPS----PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNA----------- 327
           +P A    +P+    P   +P  PA   +T   SP TP +PAP    +A           
Sbjct: 442 APTAPKKPAPTTPKEPAPTTPKEPA-PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT 500

Query: 328 ---APPSSVPPVPPSEALPPPACPSAPAP 353
              AP +   P P +   P P  P  PAP
Sbjct: 501 TKSAPTTPKEPSPTTTKEPAPTTPKEPAP 529



 Score = 29.3 bits (64), Expect = 9.1
 Identities = 19/68 (27%), Positives = 23/68 (33%), Gaps = 8/68 (11%)

Query: 294 SPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAP-----PSSVP---PVPPSEALPPP 345
           +P   +P  P G   T    P    P    P   AP     P+S     P P +     P
Sbjct: 659 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718

Query: 346 ACPSAPAP 353
             P  PAP
Sbjct: 719 TTPKEPAP 726


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 5/77 (6%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP 344
           P     + P+P   +P    G  ST S      +PAP  P   AP +   P P +   P 
Sbjct: 789 PAPTTPKKPAPKELAPTTTKGPTSTTSD-----KPAPTTPKETAPTTPKEPAPTTPKKPA 843

Query: 345 PACPSAPAPRRSIISRP 361
           P  P  P P  S +S P
Sbjct: 844 PTTPETPPPTTSEVSTP 860



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 5/70 (7%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVPPSEALP 343
           P     + P+P +     P    +T  S+P TP +PAP  P   AP +   P P +   P
Sbjct: 404 PAPTTPKEPAPTTTKEPAP----TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 459

Query: 344 PPACPSAPAP 353
            P  P  PAP
Sbjct: 460 TPTTPKEPAP 469



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 2/62 (3%)

Query: 294 SPGSQSPVVPAGAVSTGSSSPG--TPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAP 351
           +P   +P  P     T    P   T +PAP  P   AP +   P P +   P P  P  P
Sbjct: 447 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 506

Query: 352 AP 353
           AP
Sbjct: 507 AP 508



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 12/90 (13%)

Query: 284 SPLAANGQSPSPGSQSPVVPAG-AVSTGSSSPGTP---------QPAPQLPLNAAPPSSV 333
           SP      +P+    +P      A +T  S+P TP         +PAP  P   AP +  
Sbjct: 515 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 574

Query: 334 PPVPPSEALPPPACPSAPAPRRSIISRPPP 363
            P P +   P P  P  PAP  +   +P P
Sbjct: 575 KPAPTTPKEPAPTTPKEPAP--TTTKKPAP 602



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%)

Query: 291 QSPSPGSQSPVVPAGAVSTGSSSPGTPQ-PAPQLPLNAAPPSSVPPVPPSEALPPPACPS 349
           + P+P +   + P    +    +P TP+ PAP  P  AAP +   P P +   P P  P 
Sbjct: 638 EKPAPTTPEELAPT---TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 694

Query: 350 APAP 353
            PAP
Sbjct: 695 EPAP 698



 Score = 36.2 bits (82), Expect = 0.075
 Identities = 20/69 (28%), Positives = 29/69 (42%), Gaps = 3/69 (4%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPP 344
           P     + P+P ++ P  P        ++P   +PAP  P   AP +   P P +   P 
Sbjct: 459 PTPTTPKEPAPTTKEPA-PTTPKEPAPTAP--KKPAPTTPKEPAPTTPKEPAPTTTKEPS 515

Query: 345 PACPSAPAP 353
           P  P  PAP
Sbjct: 516 PTTPKEPAP 524



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 4/73 (5%)

Query: 284 SPLAANGQSPSPGSQSPVVPAGAVSTGSSSPG--TP-QPAPQLPLNAAPPSSVPPVPPSE 340
           +P      +P+    +P  P     T    P   TP +PAP  P    P +   P P ++
Sbjct: 413 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTK 472

Query: 341 ALPPPACPSAPAP 353
             P P  P  PAP
Sbjct: 473 E-PAPTTPKEPAP 484



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 6/76 (7%)

Query: 283 ASPLAANGQSPS----PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAPPSSVPPVP 337
           ++P      SP+    P   +P  PA   +    +P TP +PAP  P   AP ++  P P
Sbjct: 544 SAPTTPKEPSPTTTKEPAPTTPKEPA-PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 602

Query: 338 PSEALPPPACPSAPAP 353
            +   P P  P   AP
Sbjct: 603 TTPKEPAPTTPKETAP 618



 Score = 34.3 bits (77), Expect = 0.28
 Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 2/59 (3%)

Query: 295 PGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAP 353
           P S +P  P    +T  S+P TP+        +AP +   P P +   P P  P  PAP
Sbjct: 358 PASTTPKEPTP--TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 414



 Score = 34.3 bits (77), Expect = 0.28
 Identities = 19/76 (25%), Positives = 28/76 (36%), Gaps = 6/76 (7%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTP------QPAPQLPLNAAPPSSVPPVPP 338
           P     + P+P +     P        ++P  P      +PAP  P   AP +     P 
Sbjct: 656 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT 715

Query: 339 SEALPPPACPSAPAPR 354
           +   P P  P  PAP+
Sbjct: 716 TLKEPAPTTPKKPAPK 731



 Score = 33.9 bits (76), Expect = 0.37
 Identities = 22/81 (27%), Positives = 31/81 (38%), Gaps = 11/81 (13%)

Query: 285 PLAANGQSPSPGSQSPVVPAGAVSTG----------SSSPGTP-QPAPQLPLNAAPPSSV 333
           P     + P+P   +P       ST            ++P TP +PAP  P   AP +  
Sbjct: 720 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 779

Query: 334 PPVPPSEALPPPACPSAPAPR 354
              P +   P P  P  PAP+
Sbjct: 780 GTAPTTLKEPAPTTPKKPAPK 800



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 23/90 (25%)

Query: 285 PLAANGQSPSPGS--QSPVVPAG-AVSTGSSSPGTP---------QPAPQLPLNAAPPSS 332
           P +   + P+P +   +P  P   A +T  S+P TP         +PAP  P   AP ++
Sbjct: 358 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 417

Query: 333 VPPVP---------PSEALPPPACPSAPAP 353
             P P         P E  P P  P  PAP
Sbjct: 418 KEPAPTTTKSAPTTPKE--PAPTTPKKPAP 445



 Score = 32.7 bits (73), Expect = 0.82
 Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 6/62 (9%)

Query: 295 PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNAAP--PSSVPPVPPSEALPPPACPSAP 351
           P   +P  PA   +T   +P TP +PAP  P   AP  P  + P  P +    P  P  P
Sbjct: 584 PAPTTPKEPA-PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL--APTTPEKP 640

Query: 352 AP 353
           AP
Sbjct: 641 AP 642



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 7/65 (10%)

Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQ-PAPQLPLNAAP--PSSVPPVPPSEALPPPACP 348
           +P   +P  P     T     +P TP+ PAP  P   AP  P    P  P E  P P  P
Sbjct: 612 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE--PAPTTP 669

Query: 349 SAPAP 353
            A AP
Sbjct: 670 KAAAP 674



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 22/65 (33%), Positives = 27/65 (41%), Gaps = 7/65 (10%)

Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQP-APQLPLNAAP--PSSVPPVPPSEALPPPACP 348
           +P   +P  P     T     +P TP+  AP  P   AP  P  + P  P E  P P  P
Sbjct: 604 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE--PTPTTP 661

Query: 349 SAPAP 353
             PAP
Sbjct: 662 EEPAP 666



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 19/63 (30%), Positives = 25/63 (39%), Gaps = 3/63 (4%)

Query: 294 SPGSQSPVVPAGAVSTGSS--SPGTPQ-PAPQLPLNAAPPSSVPPVPPSEALPPPACPSA 350
           +P   +P  P     T     +P TP+ P P  P   AP +     P +   P P  P  
Sbjct: 628 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 687

Query: 351 PAP 353
           PAP
Sbjct: 688 PAP 690



 Score = 29.6 bits (65), Expect = 7.0
 Identities = 26/89 (29%), Positives = 35/89 (39%), Gaps = 20/89 (22%)

Query: 284 SPLAANGQSPS----PGSQSPVVPAGAVSTGSSSPGTP-QPAPQLPLNA----------- 327
           +P A    +P+    P   +P  PA   +T   SP TP +PAP    +A           
Sbjct: 483 APTAPKKPAPTTPKEPAPTTPKEPA-PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT 541

Query: 328 ---APPSSVPPVPPSEALPPPACPSAPAP 353
              AP +   P P +   P P  P  PAP
Sbjct: 542 TKSAPTTPKEPSPTTTKEPAPTTPKEPAP 570



 Score = 29.3 bits (64), Expect = 9.1
 Identities = 19/68 (27%), Positives = 23/68 (33%), Gaps = 8/68 (11%)

Query: 294 SPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAP-----PSSVP---PVPPSEALPPP 345
           +P   +P  P G   T    P    P    P   AP     P+S     P P +     P
Sbjct: 700 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759

Query: 346 ACPSAPAP 353
             P  PAP
Sbjct: 760 TTPKEPAP 767


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,642,348
Number of Sequences: 37866
Number of extensions: 1488942
Number of successful extensions: 26750
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 517
Number of HSP's successfully gapped in prelim test: 1407
Number of HSP's that attempted gapping in prelim test: 11892
Number of HSP's gapped (non-prelim): 9636
length of query: 520
length of database: 18,247,518
effective HSP length: 107
effective length of query: 413
effective length of database: 14,195,856
effective search space: 5862888528
effective search space used: 5862888528
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press