Guide to the Human Genome
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Search of human proteins with 171460934

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|171460934 protein phosphatase 1M isoform b [Homo sapiens]
         (247 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|171460934 protein phosphatase 1M isoform b [Homo sapiens]          493   e-140
gi|171460932 protein phosphatase 1M isoform a [Homo sapiens]          493   e-140
gi|149944715 protein phosphatase 1H (PP2C domain containing) [Ho...   272   2e-73
gi|65506328 protein phosphatase 1J (PP2C domain containing) [Hom...   244   7e-65
gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens]            55   6e-08
gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens]            55   6e-08
gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens]            55   6e-08
gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens]             55   6e-08
gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens]    54   1e-07
gi|122937199 protein phosphatase 1B-like [Homo sapiens]                51   1e-06
gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens]            49   3e-06
gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens]            49   3e-06
gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens]           49   3e-06
gi|4505999 protein phosphatase 1G [Homo sapiens]                       44   1e-04
gi|29826282 protein phosphatase 1G [Homo sapiens]                      44   1e-04
gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit ...    44   2e-04
gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo...    44   2e-04
gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit...    44   2e-04
gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit...    44   2e-04
gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit...    44   2e-04
gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit...    44   2e-04
gi|13540531 integrin-linked kinase-associated protein phosphatas...    44   2e-04
gi|7661862 protein phosphatase 1F [Homo sapiens]                       39   0.004
gi|5174703 mitogen-activated protein kinase kinase kinase 7 inte...    38   0.007
gi|41281798 mitogen-activated protein kinase kinase kinase 7 int...    38   0.007
gi|167466276 protein phosphatase 1K (PP2C domain containing) [Ho...    37   0.012
gi|30089948 protein phosphatase 1E [Homo sapiens]                      34   0.13 
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]                        28   5.6  
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]                         28   5.6  
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]                         28   5.6  

>gi|171460934 protein phosphatase 1M isoform b [Homo sapiens]
          Length = 247

 Score =  493 bits (1269), Expect = e-140
 Identities = 247/247 (100%), Positives = 247/247 (100%)

Query: 1   MGGCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPETERQRIQQLAFVYPEL 60
           MGGCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPETERQRIQQLAFVYPEL
Sbjct: 1   MGGCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPETERQRIQQLAFVYPEL 60

Query: 61  LAGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLGT 120
           LAGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLGT
Sbjct: 61  LAGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLGT 120

Query: 121 LAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLSN 180
           LAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLSN
Sbjct: 121 LAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLSN 180

Query: 181 EQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDSLTEEGQVSYDDVSVFVIPLHSQ 240
           EQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDSLTEEGQVSYDDVSVFVIPLHSQ
Sbjct: 181 EQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDSLTEEGQVSYDDVSVFVIPLHSQ 240

Query: 241 GQESSDH 247
           GQESSDH
Sbjct: 241 GQESSDH 247


>gi|171460932 protein phosphatase 1M isoform a [Homo sapiens]
          Length = 298

 Score =  493 bits (1269), Expect = e-140
 Identities = 247/247 (100%), Positives = 247/247 (100%)

Query: 1   MGGCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPETERQRIQQLAFVYPEL 60
           MGGCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPETERQRIQQLAFVYPEL
Sbjct: 52  MGGCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPETERQRIQQLAFVYPEL 111

Query: 61  LAGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLGT 120
           LAGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLGT
Sbjct: 112 LAGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLGT 171

Query: 121 LAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLSN 180
           LAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLSN
Sbjct: 172 LAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLSN 231

Query: 181 EQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDSLTEEGQVSYDDVSVFVIPLHSQ 240
           EQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDSLTEEGQVSYDDVSVFVIPLHSQ
Sbjct: 232 EQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDSLTEEGQVSYDDVSVFVIPLHSQ 291

Query: 241 GQESSDH 247
           GQESSDH
Sbjct: 292 GQESSDH 298


>gi|149944715 protein phosphatase 1H (PP2C domain containing) [Homo
           sapiens]
          Length = 514

 Score =  272 bits (695), Expect = 2e-73
 Identities = 131/241 (54%), Positives = 183/241 (75%), Gaps = 5/241 (2%)

Query: 2   GGCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPETERQRIQQLAFVYPELL 61
           GGCTAL+ + L GKLY+ANAGDSRAI++R  EI P+S EFTPETERQR+Q LAF+ P LL
Sbjct: 267 GGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLL 326

Query: 62  AGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLGTL 121
             EFT LEFPRR++  +LG+K+L+RD +M+GW+YK +E  DLK+PLI+G+G++AR++ T+
Sbjct: 327 GNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMATI 386

Query: 122 AVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLSNE 181
            V+RGLGDH L+V D+NI +KPFL S P+V + D+ + +   DDV+++ATDGLWDVLSNE
Sbjct: 387 GVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSNE 446

Query: 182 QVAWLVRSFLPG-NQEDPHRFSKLAQMLIHSTQG----KEDSLTEEGQVSYDDVSVFVIP 236
           +VA  +  FLP  + +DPHR++  AQ L+   +G    +   ++ +   S DD+SV+VIP
Sbjct: 447 EVAEAITQFLPNCDPDDPHRYTLAAQDLVMRARGVLKDRGWRISNDRLGSGDDISVYVIP 506

Query: 237 L 237
           L
Sbjct: 507 L 507


>gi|65506328 protein phosphatase 1J (PP2C domain containing) [Homo
           sapiens]
          Length = 505

 Score =  244 bits (622), Expect = 7e-65
 Identities = 126/248 (50%), Positives = 171/248 (68%), Gaps = 5/248 (2%)

Query: 2   GGCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPETERQRIQQLAFVYPELL 61
           GGC ALV + L GK+Y+ANAGDSRAI+VR  EI P+S EFTPETERQR+Q L F+ PELL
Sbjct: 258 GGCCALVVIYLLGKVYVANAGDSRAIIVRNGEIIPMSREFTPETERQRLQLLGFLKPELL 317

Query: 62  AGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLGTL 121
             EFT LEFPRR+   +LGQ++L+RD +M+GW+YK++E  DL++PL+ G+G++AR++ T+
Sbjct: 318 GSEFTHLEFPRRVLPKELGQRMLYRDQNMTGWAYKKIELEDLRFPLVCGEGKKARVMATI 377

Query: 122 AVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLSNE 181
            V+RGLGDH L+V  + + +KPFL   P+V V D+ Q E   DDV+V+ TDGLWDV ++ 
Sbjct: 378 GVTRGLGDHSLKVCSSTLPIKPFLSCFPEVRVYDLTQYEHCPDDVLVLGTDGLWDVTTDC 437

Query: 182 QVAWLVRSFLPGNQEDPH-RFSKLAQMLIHSTQGKEDS----LTEEGQVSYDDVSVFVIP 236
           +VA  V   L   + + H R++ LAQ L+   +G        L      S DD+SVFVIP
Sbjct: 438 EVAATVDRVLSAYEPNDHSRYTALAQALVLGARGTPRDRGWRLPNNKLGSGDDISVFVIP 497

Query: 237 LHSQGQES 244
           L   G  S
Sbjct: 498 LGGPGSYS 505


>gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens]
          Length = 380

 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 31/105 (29%), Positives = 60/105 (57%), Gaps = 6/105 (5%)

Query: 116 RLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLW 175
           R+ G+LAVSR LGD+  + +D     +  +   P+V  +    L  +ED+ +++A DG+W
Sbjct: 191 RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEI----LRAEEDEFIILACDGIW 246

Query: 176 DVLSNEQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDSLT 220
           DV+SNE++   V+S L  + +  +  + +    +H  +G  D+++
Sbjct: 247 DVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLH--KGSRDNMS 289


>gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens]
          Length = 327

 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 31/105 (29%), Positives = 60/105 (57%), Gaps = 6/105 (5%)

Query: 116 RLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLW 175
           R+ G+LAVSR LGD+  + +D     +  +   P+V  +    L  +ED+ +++A DG+W
Sbjct: 191 RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEI----LRAEEDEFIILACDGIW 246

Query: 176 DVLSNEQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDSLT 220
           DV+SNE++   V+S L  + +  +  + +    +H  +G  D+++
Sbjct: 247 DVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLH--KGSRDNMS 289


>gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens]
          Length = 387

 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 31/105 (29%), Positives = 60/105 (57%), Gaps = 6/105 (5%)

Query: 116 RLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLW 175
           R+ G+LAVSR LGD+  + +D     +  +   P+V  +    L  +ED+ +++A DG+W
Sbjct: 191 RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEI----LRAEEDEFIILACDGIW 246

Query: 176 DVLSNEQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDSLT 220
           DV+SNE++   V+S L  + +  +  + +    +H  +G  D+++
Sbjct: 247 DVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLH--KGSRDNMS 289


>gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens]
          Length = 479

 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 31/105 (29%), Positives = 60/105 (57%), Gaps = 6/105 (5%)

Query: 116 RLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLW 175
           R+ G+LAVSR LGD+  + +D     +  +   P+V  +    L  +ED+ +++A DG+W
Sbjct: 191 RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEI----LRAEEDEFIILACDGIW 246

Query: 176 DVLSNEQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDSLT 220
           DV+SNE++   V+S L  + +  +  + +    +H  +G  D+++
Sbjct: 247 DVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLH--KGSRDNMS 289


>gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens]
          Length = 360

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 70/221 (31%)

Query: 3   GCTALVAVSLQGKLYMANAGDSRAILVRRD-EIRPLSFEFTPET--ERQRIQQLAFVYPE 59
           G T L+A+     L +AN GDSR +L  +D    PLS +  P    ER+RI++       
Sbjct: 192 GTTCLIALLSDKDLTVANVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRIKR------- 244

Query: 60  LLAGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLG 119
             AG F                           W                      R+ G
Sbjct: 245 --AGGFISFN---------------------GSW----------------------RVQG 259

Query: 120 TLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLS 179
            LA+SR LGD+ L+ L+        ++  P +   D+D+L+    + +++A+DGLWD  S
Sbjct: 260 ILAMSRSLGDYPLKNLNV-------VIPDPDILTFDLDKLQ---PEFMILASDGLWDAFS 309

Query: 180 NEQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDSLT 220
           NE+    ++  L    ++PH F   + +L    +G  D++T
Sbjct: 310 NEEAVRFIKERL----DEPH-FGAKSIVLQSFYRGCPDNIT 345


>gi|122937199 protein phosphatase 1B-like [Homo sapiens]
          Length = 430

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 51/192 (26%), Positives = 76/192 (39%), Gaps = 61/192 (31%)

Query: 2   GGCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTP--ETERQRIQQLAFVYPE 59
           GGCTA+V +     LY+A+ GDSRA+L R   +   + +  P    ER+RI         
Sbjct: 161 GGCTAVVLLVSPRFLYLAHCGDSRAVLSRAGAVAFSTEDHRPLRPRERERI--------- 211

Query: 60  LLAGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLG 119
                                        H +G                 G  R+ R+ G
Sbjct: 212 -----------------------------HAAG-----------------GTIRRRRVEG 225

Query: 120 TLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLS 179
           +LAVSR LGD   +           + + P+V  L        ED+ +++A+DG+WD +S
Sbjct: 226 SLAVSRALGDFTYKEAPGRPPELQLVSAEPEVAAL----ARQAEDEFMLLASDGVWDTVS 281

Query: 180 NEQVAWLVRSFL 191
              +A LV S L
Sbjct: 282 GAALAGLVASRL 293


>gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens]
          Length = 382

 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 27/76 (35%), Positives = 46/76 (60%), Gaps = 3/76 (3%)

Query: 116 RLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLW 175
           R+ G+LAVSR LGD   + +      +  +   P+V   D+++ E ++D  +++A DG+W
Sbjct: 186 RVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVH--DIERSE-EDDQFIILACDGIW 242

Query: 176 DVLSNEQVAWLVRSFL 191
           DV+ NE++   VRS L
Sbjct: 243 DVMGNEELCDFVRSRL 258


>gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens]
          Length = 324

 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 27/76 (35%), Positives = 46/76 (60%), Gaps = 3/76 (3%)

Query: 116 RLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLW 175
           R+ G+LAVSR LGD   + +      +  +   P+V   D+++ E ++D  +++A DG+W
Sbjct: 186 RVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVH--DIERSE-EDDQFIILACDGIW 242

Query: 176 DVLSNEQVAWLVRSFL 191
           DV+ NE++   VRS L
Sbjct: 243 DVMGNEELCDFVRSRL 258


>gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens]
          Length = 455

 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 27/76 (35%), Positives = 46/76 (60%), Gaps = 3/76 (3%)

Query: 116 RLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLW 175
           R+ G+LAVSR LGD   + +      +  +   P+V   D+++ E ++D  +++A DG+W
Sbjct: 259 RVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVH--DIERSE-EDDQFIILACDGIW 315

Query: 176 DVLSNEQVAWLVRSFL 191
           DV+ NE++   VRS L
Sbjct: 316 DVMGNEELCDFVRSRL 331


>gi|4505999 protein phosphatase 1G [Homo sapiens]
          Length = 546

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 46/198 (23%), Positives = 82/198 (41%), Gaps = 62/198 (31%)

Query: 3   GCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPETERQRIQQLAFVYPELLA 62
           G TA+VA+    +L +ANAGDSR ++    +   +S++  PE E                
Sbjct: 328 GTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEV--------------- 372

Query: 63  GEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLGTLA 122
            E  R++        + G KV                                R+ G L 
Sbjct: 373 -ELARIK--------NAGGKVTM----------------------------DGRVNGGLN 395

Query: 123 VSRGLGDHQLRVLDTNIQLKP---FLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLS 179
           +SR +GDH  +    N  L P    + ++P + VL +      + + +V+A DG+W+V+S
Sbjct: 396 LSRAIGDHFYK---RNKNLPPEEQMISALPDIKVLTLTD----DHEFMVIACDGIWNVMS 448

Query: 180 NEQVAWLVRSFLPGNQED 197
           +++V   ++S +    E+
Sbjct: 449 SQEVVDFIQSKISQRDEN 466


>gi|29826282 protein phosphatase 1G [Homo sapiens]
          Length = 546

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 46/198 (23%), Positives = 82/198 (41%), Gaps = 62/198 (31%)

Query: 3   GCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPETERQRIQQLAFVYPELLA 62
           G TA+VA+    +L +ANAGDSR ++    +   +S++  PE E                
Sbjct: 328 GTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEV--------------- 372

Query: 63  GEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLGTLA 122
            E  R++        + G KV                                R+ G L 
Sbjct: 373 -ELARIK--------NAGGKVTM----------------------------DGRVNGGLN 395

Query: 123 VSRGLGDHQLRVLDTNIQLKP---FLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLS 179
           +SR +GDH  +    N  L P    + ++P + VL +      + + +V+A DG+W+V+S
Sbjct: 396 LSRAIGDHFYK---RNKNLPPEEQMISALPDIKVLTLTD----DHEFMVIACDGIWNVMS 448

Query: 180 NEQVAWLVRSFLPGNQED 197
           +++V   ++S +    E+
Sbjct: 449 SQEVVDFIQSKISQRDEN 466


>gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit 1
           isoform 3 precursor [Homo sapiens]
          Length = 537

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 55/203 (27%), Positives = 88/203 (43%), Gaps = 46/203 (22%)

Query: 3   GCTALVAVSLQGKLYMANAGDSRAILVRRDE-----IRPLSFEFTPETERQRIQQLAFVY 57
           G TA VA      L++AN GDSRA+L  ++E        LS +   + ER+ +++L   +
Sbjct: 271 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERE-LERLKLEH 329

Query: 58  PELLAGEFTR------LEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQ 111
           P+  A    +      L  P R  GD     V F+      WS       DL+  +I   
Sbjct: 330 PKSEAKSVVKQDRLLGLLMPFRAFGD-----VKFK------WSI------DLQKRVIESG 372

Query: 112 GRQARLLGTLAVSRGLGDHQL-RVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMA 170
             Q            L D++  + +  N    P+L + P+VT   +      +D  +V+A
Sbjct: 373 PDQ------------LNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRP----QDKFLVLA 416

Query: 171 TDGLWDVLSNEQVAWLVRSFLPG 193
           TDGLW+ +  + V  +V  +L G
Sbjct: 417 TDGLWETMHRQDVVRIVGEYLTG 439


>gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo
           sapiens]
          Length = 529

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 40/131 (30%), Positives = 59/131 (45%), Gaps = 35/131 (26%)

Query: 84  LFRDHHMSGWSYKRVEKSDLKYPLIHGQGR----QARLLGTLAVSRGLGDHQLR------ 133
           L RDH+    ++ + E S LK      + R    + RLLG L   R  GD QL+      
Sbjct: 305 LTRDHN----AWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ 360

Query: 134 --VLDTNIQLK---------------PFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWD 176
             +L+     +               P+L + P+VT   +      +D  +V+A+DGLWD
Sbjct: 361 RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRP----QDKFLVLASDGLWD 416

Query: 177 VLSNEQVAWLV 187
           +LSNE V  LV
Sbjct: 417 MLSNEDVVRLV 427


>gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit 1
           isoform 3 precursor [Homo sapiens]
          Length = 537

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 55/203 (27%), Positives = 88/203 (43%), Gaps = 46/203 (22%)

Query: 3   GCTALVAVSLQGKLYMANAGDSRAILVRRDE-----IRPLSFEFTPETERQRIQQLAFVY 57
           G TA VA      L++AN GDSRA+L  ++E        LS +   + ER+ +++L   +
Sbjct: 271 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERE-LERLKLEH 329

Query: 58  PELLAGEFTR------LEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQ 111
           P+  A    +      L  P R  GD     V F+      WS       DL+  +I   
Sbjct: 330 PKSEAKSVVKQDRLLGLLMPFRAFGD-----VKFK------WSI------DLQKRVIESG 372

Query: 112 GRQARLLGTLAVSRGLGDHQL-RVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMA 170
             Q            L D++  + +  N    P+L + P+VT   +      +D  +V+A
Sbjct: 373 PDQ------------LNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRP----QDKFLVLA 416

Query: 171 TDGLWDVLSNEQVAWLVRSFLPG 193
           TDGLW+ +  + V  +V  +L G
Sbjct: 417 TDGLWETMHRQDVVRIVGEYLTG 439


>gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit 1
           isoform 2 [Homo sapiens]
          Length = 562

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 55/203 (27%), Positives = 88/203 (43%), Gaps = 46/203 (22%)

Query: 3   GCTALVAVSLQGKLYMANAGDSRAILVRRDE-----IRPLSFEFTPETERQRIQQLAFVY 57
           G TA VA      L++AN GDSRA+L  ++E        LS +   + ER+ +++L   +
Sbjct: 296 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERE-LERLKLEH 354

Query: 58  PELLAGEFTR------LEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQ 111
           P+  A    +      L  P R  GD     V F+      WS       DL+  +I   
Sbjct: 355 PKSEAKSVVKQDRLLGLLMPFRAFGD-----VKFK------WSI------DLQKRVIESG 397

Query: 112 GRQARLLGTLAVSRGLGDHQL-RVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMA 170
             Q            L D++  + +  N    P+L + P+VT   +      +D  +V+A
Sbjct: 398 PDQ------------LNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRP----QDKFLVLA 441

Query: 171 TDGLWDVLSNEQVAWLVRSFLPG 193
           TDGLW+ +  + V  +V  +L G
Sbjct: 442 TDGLWETMHRQDVVRIVGEYLTG 464


>gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit 1
           isoform 2 [Homo sapiens]
          Length = 562

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 55/203 (27%), Positives = 88/203 (43%), Gaps = 46/203 (22%)

Query: 3   GCTALVAVSLQGKLYMANAGDSRAILVRRDE-----IRPLSFEFTPETERQRIQQLAFVY 57
           G TA VA      L++AN GDSRA+L  ++E        LS +   + ER+ +++L   +
Sbjct: 296 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERE-LERLKLEH 354

Query: 58  PELLAGEFTR------LEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQ 111
           P+  A    +      L  P R  GD     V F+      WS       DL+  +I   
Sbjct: 355 PKSEAKSVVKQDRLLGLLMPFRAFGD-----VKFK------WSI------DLQKRVIESG 397

Query: 112 GRQARLLGTLAVSRGLGDHQL-RVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMA 170
             Q            L D++  + +  N    P+L + P+VT   +      +D  +V+A
Sbjct: 398 PDQ------------LNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRP----QDKFLVLA 441

Query: 171 TDGLWDVLSNEQVAWLVRSFLPG 193
           TDGLW+ +  + V  +V  +L G
Sbjct: 442 TDGLWETMHRQDVVRIVGEYLTG 464


>gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit 1
           isoform 1 [Homo sapiens]
          Length = 596

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 55/203 (27%), Positives = 88/203 (43%), Gaps = 46/203 (22%)

Query: 3   GCTALVAVSLQGKLYMANAGDSRAILVRRDE-----IRPLSFEFTPETERQRIQQLAFVY 57
           G TA VA      L++AN GDSRA+L  ++E        LS +   + ER+ +++L   +
Sbjct: 330 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERE-LERLKLEH 388

Query: 58  PELLAGEFTR------LEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQ 111
           P+  A    +      L  P R  GD     V F+      WS       DL+  +I   
Sbjct: 389 PKSEAKSVVKQDRLLGLLMPFRAFGD-----VKFK------WSI------DLQKRVIESG 431

Query: 112 GRQARLLGTLAVSRGLGDHQL-RVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMA 170
             Q            L D++  + +  N    P+L + P+VT   +      +D  +V+A
Sbjct: 432 PDQ------------LNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRP----QDKFLVLA 475

Query: 171 TDGLWDVLSNEQVAWLVRSFLPG 193
           TDGLW+ +  + V  +V  +L G
Sbjct: 476 TDGLWETMHRQDVVRIVGEYLTG 498


>gi|13540531 integrin-linked kinase-associated protein phosphatase
           2C [Homo sapiens]
          Length = 392

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 50/190 (26%), Positives = 80/190 (42%), Gaps = 61/190 (32%)

Query: 3   GCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPETERQRIQQLAFVYPELLA 62
           G TA   +++   LY+AN GDSRAIL R +E            E Q+   L+      L+
Sbjct: 216 GSTATCVLAVDNILYIANLGDSRAILCRYNE------------ESQKHAALS------LS 257

Query: 63  GEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLGTLA 122
            E    ++  R+                      R++K+        G  R  R+LG L 
Sbjct: 258 KEHNPTQYEERM----------------------RIQKAG-------GNVRDGRVLGVLE 288

Query: 123 VSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDD-VVVMATDGLWDVLSNE 181
           VSR +GD Q +        +  + SVP     D+ + +L  +D  +++A DGL+ V + E
Sbjct: 289 VSRSIGDGQYK--------RCGVTSVP-----DIRRCQLTPNDRFILLACDGLFKVFTPE 335

Query: 182 QVAWLVRSFL 191
           +    + S L
Sbjct: 336 EAVNFILSCL 345


>gi|7661862 protein phosphatase 1F [Homo sapiens]
          Length = 454

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 56/235 (23%), Positives = 93/235 (39%), Gaps = 79/235 (33%)

Query: 3   GCTALVAVSLQGKLYMANAGDSRAILVRRDEIRPLSFEFTPET--ERQRIQQLAFVYPEL 60
           G T + A+     L++A  GDS+ ILV++ ++  L     PE   E+ RI+ L       
Sbjct: 254 GTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEAL------- 306

Query: 61  LAGEFTRLEFPRRLKGDDLGQKVLFRDHHMSGWSYKRVEKSDLKYPLIHGQGRQARLLGT 120
             G F                       HM  W                      R+ GT
Sbjct: 307 --GGFVS---------------------HMDCW----------------------RVNGT 321

Query: 121 LAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLWDVLSN 180
           LAVSR +GD         +  KP++            +     +D +++A DG +DV+ +
Sbjct: 322 LAVSRAIGD---------VFQKPYVSGEADAA----SRALTGSEDYLLLACDGFFDVVPH 368

Query: 181 EQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDSLTEEGQVSYDDVSVFVI 235
           ++V  LV+S L   Q    R   +A+ L+ + +       E G  S+D+++V V+
Sbjct: 369 QEVVGLVQSHLTRQQGSGLR---VAEELVAAAR-------ERG--SHDNITVMVV 411


>gi|5174703 mitogen-activated protein kinase kinase kinase 7
           interacting protein 1 isoform alpha [Homo sapiens]
          Length = 504

 Score = 38.1 bits (87), Expect = 0.007
 Identities = 23/58 (39%), Positives = 34/58 (58%), Gaps = 6/58 (10%)

Query: 2   GGCTALVAVSLQGKLYMANAGDSRAILVRRD----EIRPLSFEFTPETERQ--RIQQL 53
           GG  A+VAV L  KLY+AN G +RA+L +      ++  L+ + T E E +  R+ QL
Sbjct: 164 GGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQL 221


>gi|41281798 mitogen-activated protein kinase kinase kinase 7
           interacting protein 1 isoform beta [Homo sapiens]
          Length = 462

 Score = 38.1 bits (87), Expect = 0.007
 Identities = 23/58 (39%), Positives = 34/58 (58%), Gaps = 6/58 (10%)

Query: 2   GGCTALVAVSLQGKLYMANAGDSRAILVRRD----EIRPLSFEFTPETERQ--RIQQL 53
           GG  A+VAV L  KLY+AN G +RA+L +      ++  L+ + T E E +  R+ QL
Sbjct: 164 GGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQL 221


>gi|167466276 protein phosphatase 1K (PP2C domain containing) [Homo
           sapiens]
          Length = 372

 Score = 37.4 bits (85), Expect = 0.012
 Identities = 23/53 (43%), Positives = 35/53 (66%), Gaps = 3/53 (5%)

Query: 3   GCTALVAVSLQG-KLYMANAGDSRAILVRRDEIRPLSFEFTPE--TERQRIQQ 52
           G TA VA+   G +L +A+ GDSRAIL R+ +   L+ + TPE   E++RI++
Sbjct: 187 GTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKK 239


>gi|30089948 protein phosphatase 1E [Homo sapiens]
          Length = 755

 Score = 33.9 bits (76), Expect = 0.13
 Identities = 30/109 (27%), Positives = 53/109 (48%), Gaps = 22/109 (20%)

Query: 116 RLLGTLAVSRGLGDHQLRVLDTNIQLKPFLL--SVPQVTVLDVDQLELQEDDVVVMATDG 173
           R+ G+L+VSR +GD          + KP++   +    TVLD        +D +++A DG
Sbjct: 392 RVNGSLSVSRAIGD---------AEHKPYICGDADSASTVLD------GTEDYLILACDG 436

Query: 174 LWDVLSNEQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQ--GKEDSLT 220
            +D ++ ++   +V   L  N  D    S +A  L+ S +  G  D++T
Sbjct: 437 FYDTVNPDEAVKVVSDHLKENNGDS---SMVAHKLVASARDAGSSDNIT 482


>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
          Length = 1897

 Score = 28.5 bits (62), Expect = 5.6
 Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 23/94 (24%)

Query: 155  DVDQLELQEDDVVVM-ATDGLWDVLSNEQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQ 213
            ++  LEL EDD V   AT+GL D+L  E+        LPG++                  
Sbjct: 1655 ELGSLELVEDDTVDSDATNGLIDLLEQEE-GQRSEEKLPGSK------------------ 1695

Query: 214  GKEDSLTEEGQVSYDDVSVFVIPLHSQGQESSDH 247
             ++D  T  GQ S ++VS  ++  H +GQ    H
Sbjct: 1696 -RQDDATGAGQDSENEVS--LVSGHQRGQARITH 1726


>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
          Length = 1881

 Score = 28.5 bits (62), Expect = 5.6
 Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 23/94 (24%)

Query: 155  DVDQLELQEDDVVVM-ATDGLWDVLSNEQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQ 213
            ++  LEL EDD V   AT+GL D+L  E+        LPG++                  
Sbjct: 1614 ELGSLELVEDDTVDSDATNGLIDLLEQEE-GQRSEEKLPGSK------------------ 1654

Query: 214  GKEDSLTEEGQVSYDDVSVFVIPLHSQGQESSDH 247
             ++D  T  GQ S ++VS  ++  H +GQ    H
Sbjct: 1655 -RQDDATGAGQDSENEVS--LVSGHQRGQARITH 1685


>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
          Length = 1880

 Score = 28.5 bits (62), Expect = 5.6
 Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 23/94 (24%)

Query: 155  DVDQLELQEDDVVVM-ATDGLWDVLSNEQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQ 213
            ++  LEL EDD V   AT+GL D+L  E+        LPG++                  
Sbjct: 1614 ELGSLELVEDDTVDSDATNGLIDLLEQEE-GQRSEEKLPGSK------------------ 1654

Query: 214  GKEDSLTEEGQVSYDDVSVFVIPLHSQGQESSDH 247
             ++D  T  GQ S ++VS  ++  H +GQ    H
Sbjct: 1655 -RQDDATGAGQDSENEVS--LVSGHQRGQARITH 1685


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,863,470
Number of Sequences: 37866
Number of extensions: 372032
Number of successful extensions: 838
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 779
Number of HSP's gapped (non-prelim): 56
length of query: 247
length of database: 18,247,518
effective HSP length: 100
effective length of query: 147
effective length of database: 14,460,918
effective search space: 2125754946
effective search space used: 2125754946
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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