BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|170784831 chromosome 1 open reading frame 9 protein isoform 2 [Homo sapiens] (1210 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|170784831 chromosome 1 open reading frame 9 protein isoform 2... 2389 0.0 gi|7656940 chromosome 1 open reading frame 9 protein isoform 1 [... 2364 0.0 gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 46 2e-04 gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa... 45 3e-04 gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa... 45 3e-04 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 42 0.005 gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 42 0.005 gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens] 41 0.006 gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens] 41 0.006 gi|133778961 testis expressed 15 [Homo sapiens] 40 0.010 gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 40 0.013 gi|109255236 centrosomal protein 63 isoform d [Homo sapiens] 40 0.013 gi|109255226 centrosomal protein 63 isoform c [Homo sapiens] 40 0.013 gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 40 0.013 gi|242117996 hypothetical protein LOC392307 [Homo sapiens] 40 0.018 gi|109255234 centrosomal protein 290kDa [Homo sapiens] 40 0.018 gi|51988900 XPG-complementing protein [Homo sapiens] 40 0.018 gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom... 40 0.018 gi|109659849 filamin A interacting protein 1-like isoform 2 [Hom... 40 0.018 gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom... 40 0.018 gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 39 0.023 gi|14165274 golgi-associated microtubule-binding protein HOOK3 [... 39 0.023 gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 39 0.030 gi|213385278 TNF receptor-associated factor 3 interacting protei... 39 0.030 gi|91982772 mucin 17 [Homo sapiens] 39 0.030 gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 39 0.039 gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 39 0.039 gi|222537714 taxilin beta [Homo sapiens] 38 0.051 gi|20070262 TNF receptor-associated factor 3 interacting protein... 38 0.051 gi|83716024 kinesin family member 21B [Homo sapiens] 38 0.051 >gi|170784831 chromosome 1 open reading frame 9 protein isoform 2 [Homo sapiens] Length = 1210 Score = 2389 bits (6192), Expect = 0.0 Identities = 1210/1210 (100%), Positives = 1210/1210 (100%) Query: 1 MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKKN 60 MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKKN Sbjct: 1 MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKKN 60 Query: 61 TESKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIP 120 TESKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIP Sbjct: 61 TESKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIP 120 Query: 121 IAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEF 180 IAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEF Sbjct: 121 IAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEF 180 Query: 181 ESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKK 240 ESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKK Sbjct: 181 ESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKK 240 Query: 241 VMEVEKEKSQSMHASSNGGSHATKKVQKNRNNYASVECGAKILAANPEAKSTSAILIENM 300 VMEVEKEKSQSMHASSNGGSHATKKVQKNRNNYASVECGAKILAANPEAKSTSAILIENM Sbjct: 241 VMEVEKEKSQSMHASSNGGSHATKKVQKNRNNYASVECGAKILAANPEAKSTSAILIENM 300 Query: 301 DLYMLNPCSTKIWFVIELCEPIQVKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGT 360 DLYMLNPCSTKIWFVIELCEPIQVKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGT Sbjct: 301 DLYMLNPCSTKIWFVIELCEPIQVKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGT 360 Query: 361 FHGRDERNVQSFPLDEQMYAKYVKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQ 420 FHGRDERNVQSFPLDEQMYAKYVKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQ Sbjct: 361 FHGRDERNVQSFPLDEQMYAKYVKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQ 420 Query: 421 YHSERQELFDEDYDYPLDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGN 480 YHSERQELFDEDYDYPLDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGN Sbjct: 421 YHSERQELFDEDYDYPLDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGN 480 Query: 481 KSISENATATAAPKMPESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEE 540 KSISENATATAAPKMPESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEE Sbjct: 481 KSISENATATAAPKMPESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEE 540 Query: 541 EEEASPSTVTLLGSGEQEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALY 600 EEEASPSTVTLLGSGEQEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALY Sbjct: 541 EEEASPSTVTLLGSGEQEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALY 600 Query: 601 RQRSRTALSKGKDYLVLAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSS 660 RQRSRTALSKGKDYLVLAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSS Sbjct: 601 RQRSRTALSKGKDYLVLAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSS 660 Query: 661 SMHQDDLVNHTVDAVELEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPV 720 SMHQDDLVNHTVDAVELEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPV Sbjct: 661 SMHQDDLVNHTVDAVELEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPV 720 Query: 721 IPQESSVEIDNETEQKSESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETI 780 IPQESSVEIDNETEQKSESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETI Sbjct: 721 IPQESSVEIDNETEQKSESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETI 780 Query: 781 VPPINTATVPDNEDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTA 840 VPPINTATVPDNEDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTA Sbjct: 781 VPPINTATVPDNEDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTA 840 Query: 841 TDFYAELQNSTDLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYR 900 TDFYAELQNSTDLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYR Sbjct: 841 TDFYAELQNSTDLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYR 900 Query: 901 KQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELK 960 KQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELK Sbjct: 901 KQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELK 960 Query: 961 REVSDRQSYLVISLVLCVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYD 1020 REVSDRQSYLVISLVLCVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYD Sbjct: 961 REVSDRQSYLVISLVLCVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYD 1020 Query: 1021 DMNLKRRTSFPLMRSKSLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPE 1080 DMNLKRRTSFPLMRSKSLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPE Sbjct: 1021 DMNLKRRTSFPLMRSKSLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPE 1080 Query: 1081 EPLHPIANGDIKGRKPFTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISAC 1140 EPLHPIANGDIKGRKPFTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISAC Sbjct: 1081 EPLHPIANGDIKGRKPFTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISAC 1140 Query: 1141 TSLCNGQSQKTKTEKRALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGT 1200 TSLCNGQSQKTKTEKRALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGT Sbjct: 1141 TSLCNGQSQKTKTEKRALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGT 1200 Query: 1201 FGVTAVSGHI 1210 FGVTAVSGHI Sbjct: 1201 FGVTAVSGHI 1210 >gi|7656940 chromosome 1 open reading frame 9 protein isoform 1 [Homo sapiens] Length = 1254 Score = 2364 bits (6126), Expect = 0.0 Identities = 1210/1254 (96%), Positives = 1210/1254 (96%), Gaps = 44/1254 (3%) Query: 1 MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKK- 59 MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKK Sbjct: 1 MKKHRRALALVSCLFLCSLVWLPSWRVCCKESSSASASSYYSQDDNCALENEDVQFQKKD 60 Query: 60 ------------------------------------NTESKKLSPPVVETLPTVDLHEES 83 NTESKKLSPPVVETLPTVDLHEES Sbjct: 61 EREGPINAESLGKSGSNLPISPKEHKLKDDSIVDVQNTESKKLSPPVVETLPTVDLHEES 120 Query: 84 SNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDAS 143 SNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDAS Sbjct: 121 SNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDAS 180 Query: 144 APIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDN 203 APIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDN Sbjct: 181 APIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDN 240 Query: 204 LKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHAT 263 LKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHAT Sbjct: 241 LKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHAT 300 Query: 264 KKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQ 323 KKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQ Sbjct: 301 KKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQ 360 Query: 324 VKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYV 383 VKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYV Sbjct: 361 VKQLDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYV 420 Query: 384 -------KVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYHSERQELFDEDYDYP 436 KVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYHSERQELFDEDYDYP Sbjct: 421 KMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYHSERQELFDEDYDYP 480 Query: 437 LDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATAAPKMP 496 LDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATAAPKMP Sbjct: 481 LDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATAAPKMP 540 Query: 497 ESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEEEEEASPSTVTLLGSGE 556 ESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEEEEEASPSTVTLLGSGE Sbjct: 541 ESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEEEEEASPSTVTLLGSGE 600 Query: 557 QEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLV 616 QEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLV Sbjct: 601 QEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLV 660 Query: 617 LAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVE 676 LAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVE Sbjct: 661 LAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVE 720 Query: 677 LEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQK 736 LEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQK Sbjct: 721 LEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQK 780 Query: 737 SESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGE 796 SESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGE Sbjct: 781 SESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGE 840 Query: 797 AKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYA 856 AKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYA Sbjct: 841 AKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYA 900 Query: 857 NGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK 916 NGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK Sbjct: 901 NGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK 960 Query: 917 LQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVL 976 LQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVL Sbjct: 961 LQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVL 1020 Query: 977 CVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSK 1036 CVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSK Sbjct: 1021 CVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSK 1080 Query: 1037 SLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPEEPLHPIANGDIKGRKP 1096 SLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPEEPLHPIANGDIKGRKP Sbjct: 1081 SLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKIEKIETIKPEEPLHPIANGDIKGRKP 1140 Query: 1097 FTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQSQKTKTEKR 1156 FTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQSQKTKTEKR Sbjct: 1141 FTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQSQKTKTEKR 1200 Query: 1157 ALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVSGHI 1210 ALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVSGHI Sbjct: 1201 ALKRRRSKVQDQGKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVSGHI 1254 >gi|34878904 synaptonemal complex protein 1 [Homo sapiens] Length = 976 Score = 45.8 bits (107), Expect = 2e-04 Identities = 44/200 (22%), Positives = 90/200 (45%), Gaps = 33/200 (16%) Query: 796 EAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGY 855 E K I D KQ + ++ ++ E+E +D L L + D +L+ T L Sbjct: 256 EYKKEINDKEKQVSLLLI------QITEKENKMKD--LTFLLEESRDKVNQLEEKTKLQS 307 Query: 856 AN-----GNLVHGSNQKESVFMRLNNRI---KALEVNMSLSGRYLEELSQRYRKQMEEMQ 907 N H + + E + + L + KALE ++ ++ + + +L++ QMEE Sbjct: 308 ENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESN 367 Query: 908 KA----------FNKTIVKLQNTSRIAEEQDQRQTEAIQLL-------QAQLTNMTQLVS 950 KA F T+ L+ R +++ ++ + +++L ++L MT+L + Sbjct: 368 KARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTN 427 Query: 951 NLSATVAELKREVSDRQSYL 970 N + ELK+ + ++++ L Sbjct: 428 NKEVELEELKKVLGEKETLL 447 Score = 36.2 bits (82), Expect = 0.19 Identities = 75/391 (19%), Positives = 158/391 (40%), Gaps = 41/391 (10%) Query: 566 ESETQIFCSELTTICCISSFSEYIYKWCSVRVALYRQRSRTALSKGKDYLVLAQPPLLLP 625 E ETQ+ S +E+ CS+ L ++ R L K +D L + L Sbjct: 358 EKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQR--LEKNEDQLKILTMELQKK 415 Query: 626 AESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVELEPSHSQTL 685 + S L+ ++ N +E E VLG+ + ++++ + EL+ + + + Sbjct: 416 S-----SELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAE--ELKGTEQELI 468 Query: 686 SQSLLLDITPEINPLP--KIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQKSESFS-- 741 LL E++ L ++ S +Y + + ++ E++NE + +E S Sbjct: 469 G--LLQAREKEVHDLEIQLTAITTSEQYYSKEV------KDLKTELENEKLKNTELTSHC 520 Query: 742 ---SIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGEAK 798 S+E +T ET+ + + N +ED+N+ + K E ++ I + + Sbjct: 521 NKLSLENKELTQETSDMTLELKNQ-QEDINNNK---KQEERMLKQIENLQETETQ----L 572 Query: 799 MNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYANG 858 N + ++ L D K EE LR + ELQ G Sbjct: 573 RNELEYVREELKQKRDEVKCKLDKSEENCNN---LRKQVENKNKYIEELQQENKALKKKG 629 Query: 859 NLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQ 918 +++ +V+ ++ LE+ + + + E++ Y+K++E+ + + + +++ Sbjct: 630 T---AESKQLNVY---EIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVE 683 Query: 919 NTSRIAEEQDQRQTEAIQLLQAQLTNMTQLV 949 IA+E + Q E + Q ++ M L+ Sbjct: 684 KAKVIADEAVKLQKEIDKRCQHKIAEMVALM 714 Score = 32.3 bits (72), Expect = 2.8 Identities = 81/381 (21%), Positives = 147/381 (38%), Gaps = 61/381 (16%) Query: 721 IPQESSVEIDNETEQKSESFSSIEKPSITYETNKVNELMDNI--IKEDVNSMQIFTKL-S 777 + QE EI+++ +Q S + IT + NK+ +L + ++ VN ++ TKL S Sbjct: 253 LEQEYKKEINDKEKQVS-----LLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQS 307 Query: 778 ETIVPPINTA--TVPDNEDGEAKMNIADTAKQTL-----ISVVDSSSLPEVKEEEQSPED 830 E + I + ED + + + + ++ L I+ L E KE + + Sbjct: 308 ENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESN 367 Query: 831 ALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGR 890 T+F + + +L ++ + +++K L + + Sbjct: 368 KARAAHSFVVTEFETTVCSLEEL----------LRTEQQRLEKNEDQLKILTMELQKKSS 417 Query: 891 YLEE---LSQRYRKQMEEMQKAFNKTIVKLQNTS---RIAEEQDQRQTEAIQLLQA---- 940 LEE L+ ++EE++K + L +IAEE + E I LLQA Sbjct: 418 ELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQAREKE 477 Query: 941 ------QLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVLCVVLGLMLCMQRCRNTSQ 994 QLT +T S V +LK E+ + + C L L + +Q Sbjct: 478 VHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSL-----ENKELTQ 532 Query: 995 FDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLMRSKSLQLTGKEVDPNDLYIVE 1054 D +L + D N K++ L + ++LQ T ++ Y+ E Sbjct: 533 ETSDMTLELKNQQE-----------DINNNKKQEERMLKQIENLQETETQLRNELEYVRE 581 Query: 1055 PLKFSPEKKKKRCKYKIEKIE 1075 LK +K+ K K++K E Sbjct: 582 ELK----QKRDEVKCKLDKSE 598 >gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sapiens] Length = 1782 Score = 45.4 bits (106), Expect = 3e-04 Identities = 59/261 (22%), Positives = 105/261 (40%), Gaps = 33/261 (12%) Query: 24 SWRVCCKESSSASASSYYSQDDNCALENEDVQFQKKNTESKKLSPPVVETLPTVDLHEES 83 S ++ E + + + + + E E V+ + S P + P + Sbjct: 347 SEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEEQVSGSQGPSEEKPAPLATEVFDE 406 Query: 84 SNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPI-------AKPSETEQSET---- 132 V E V + S+ E T K + E +G++P A+P E E ++ Sbjct: 407 KIEVHQEEVVAEVHVSTVEERTEEQKTEVEETAGSVPAEELVEMDAEPQEAEPAKELVKL 466 Query: 133 --DCDVGEALDASAPIEQPSFV--SPPDSLVGQHIENVSSSHG---KGKITKSEFES--- 182 C GE A + V PP+ +V + +E +SS +G K F S Sbjct: 467 KETCVSGEDPTQGADLSPDEKVLSKPPEGVVSE-VEMLSSQERMKVQGSPLKKLFTSTGL 525 Query: 183 -KVSASEQ----GGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEW 237 K+S +Q GGGD +S + + S + G+ +S +SP++PE+I + Sbjct: 526 KKLSGKKQKGKRGGGDEESGEHTQVPADSPDSQEEQKGE---SSASSPEEPEEITCLE-- 580 Query: 238 KKKVMEVEKEKSQSMHASSNG 258 K + EV+++ A+S+G Sbjct: 581 -KGLAEVQQDGEAEEGATSDG 600 >gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sapiens] Length = 1684 Score = 45.4 bits (106), Expect = 3e-04 Identities = 59/261 (22%), Positives = 105/261 (40%), Gaps = 33/261 (12%) Query: 24 SWRVCCKESSSASASSYYSQDDNCALENEDVQFQKKNTESKKLSPPVVETLPTVDLHEES 83 S ++ E + + + + + E E V+ + S P + P + Sbjct: 249 SEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEEQVSGSQGPSEEKPAPLATEVFDE 308 Query: 84 SNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPI-------AKPSETEQSET---- 132 V E V + S+ E T K + E +G++P A+P E E ++ Sbjct: 309 KIEVHQEEVVAEVHVSTVEERTEEQKTEVEETAGSVPAEELVEMDAEPQEAEPAKELVKL 368 Query: 133 --DCDVGEALDASAPIEQPSFV--SPPDSLVGQHIENVSSSHG---KGKITKSEFES--- 182 C GE A + V PP+ +V + +E +SS +G K F S Sbjct: 369 KETCVSGEDPTQGADLSPDEKVLSKPPEGVVSE-VEMLSSQERMKVQGSPLKKLFTSTGL 427 Query: 183 -KVSASEQ----GGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEW 237 K+S +Q GGGD +S + + S + G+ +S +SP++PE+I + Sbjct: 428 KKLSGKKQKGKRGGGDEESGEHTQVPADSPDSQEEQKGE---SSASSPEEPEEITCLE-- 482 Query: 238 KKKVMEVEKEKSQSMHASSNG 258 K + EV+++ A+S+G Sbjct: 483 -KGLAEVQQDGEAEEGATSDG 502 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 41.6 bits (96), Expect = 0.005 Identities = 52/243 (21%), Positives = 95/243 (39%), Gaps = 9/243 (3%) Query: 33 SSASASSYYSQDDNCALENEDVQFQKKNTESKKLSPPVVETLPTVDLHEESSNAVVDSET 92 SS S+ S S D + + E+ D +++S S ++ + D + S ++ DS Sbjct: 1066 SSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSS----DSSDSSDSSDSSDSS--DSSD 1119 Query: 93 VENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDASAPIEQPSFV 152 N S SS S + S D S + ++ S++ S D ++ D+S + Sbjct: 1120 SSNSSDSSDSSDSSDSS-DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1178 Query: 153 SPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDNLKNESSDYT 212 + DS + S S + S S S S S+ ++ + NESSD + Sbjct: 1179 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSS 1238 Query: 213 KPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHATKKVQKNRNN 272 D +S +S D D + + +S+S + ++NG + + N+ Sbjct: 1239 DSSDSSDSSNSS--DSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNH 1296 Query: 273 YAS 275 S Sbjct: 1297 STS 1299 Score = 37.4 bits (85), Expect = 0.087 Identities = 42/229 (18%), Positives = 94/229 (41%), Gaps = 17/229 (7%) Query: 32 SSSASASSYYSQDDNCALENEDVQFQKKNTESKKLSPPVVETLPTVDLHEESSNAVVDSE 91 S S S++S S D + + ++ D +++S S + +SS++ S+ Sbjct: 724 SDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSS--------DSSDSSDSSD 775 Query: 92 TVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDASAPIEQPSF 151 + ++ +SS +++ + S + S + S +D D + D+S + Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDS 835 Query: 152 VSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDNLKNESSDY 211 + DS ++ SS G + + +S S+ D ++ ++SD+ ++S++ Sbjct: 836 SNSSDS-----SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS--SDSNES 888 Query: 212 TKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGS 260 + D +S +S D D + + S+S ++S N S Sbjct: 889 SNSSDSSDSSNSSDSDSSDSSNSSD--SSDSSNSSDSSESSNSSDNSNS 935 Score = 36.6 bits (83), Expect = 0.15 Identities = 46/233 (19%), Positives = 90/233 (38%), Gaps = 6/233 (2%) Query: 33 SSASASSYYSQDDNCALENEDVQFQKKNTESKKLSPPVVETLPTVDLHEESSNAVVDSET 92 SS S+ S S+ D+ E++ K+ S S + + D SSN+ S++ Sbjct: 613 SSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSD-SSNSSNSSDSSDS 671 Query: 93 VENISSSSTSEITPIS-KLDEIEKSGTIPIAKPSETEQSETDCDVGEALDASAPIEQPSF 151 ++ SSS+S+ + S D + S + + S++ S++ + S+ + + Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNS 731 Query: 152 VSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDNLKNESSDY 211 DS + S S + S S S S S+ +++ + N+SS+ Sbjct: 732 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNS 791 Query: 212 TKPGD----IDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGS 260 + D D ++ + D D D + S S ++S + S Sbjct: 792 SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS 844 Score = 35.8 bits (81), Expect = 0.25 Identities = 39/195 (20%), Positives = 76/195 (38%), Gaps = 5/195 (2%) Query: 31 ESSSASASSYYSQDDNCALENEDVQFQKKNTESKKLSPPVVETLPTVDLHEESSNAVVDS 90 +SS++S SS S + N ++ S ++ + D + S+ DS Sbjct: 802 DSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS 861 Query: 91 ETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDASAPIEQPS 150 + S SS S + D + S + + S++ S D + +++ S Sbjct: 862 SNSSDSSDSSDSS----NSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDS 917 Query: 151 FVSPPDSLVGQHIENVSSSHGKGKITKSEF-ESKVSASEQGGGDPKSALNASDNLKNESS 209 S S +N +SS S+ +S S+ D ++ ++SD+ ++SS Sbjct: 918 SNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS 977 Query: 210 DYTKPGDIDPTSVAS 224 D + D +S +S Sbjct: 978 DSSNSSDSSDSSDSS 992 Score = 35.0 bits (79), Expect = 0.43 Identities = 38/213 (17%), Positives = 79/213 (37%), Gaps = 6/213 (2%) Query: 82 ESSNAVVDSETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALD 141 +S DS ++ SS++S+ + S D + + + + ++ +D ++ D Sbjct: 541 DSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS---SDSDSSDSDSSDSSDSDSSD 597 Query: 142 ASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNAS 201 +S + DS + S K + S+ +SK +S+ D ++S Sbjct: 598 SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSS 657 Query: 202 DNLKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSH 261 D+ N S+ D + +S D + + D E S S +S + S Sbjct: 658 DS-SNSSNSSDSSDSSDSSDSSSSSDSSN--SSDSSDSSDSSNSSESSDSSDSSDSDSSD 714 Query: 262 ATKKVQKNRNNYASVECGAKILAANPEAKSTSA 294 ++ N ++ S ++N S S+ Sbjct: 715 SSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS 747 Score = 34.3 bits (77), Expect = 0.74 Identities = 43/246 (17%), Positives = 94/246 (38%), Gaps = 18/246 (7%) Query: 32 SSSASASSYYSQDDNCALENEDVQFQKKNTESKKLSPPVVETLPTVDLHEESSNAVVDSE 91 +SS S+ S S D + + ++ +++S S +SSN+ S+ Sbjct: 697 NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDS-----------SDSSNSSDSSD 745 Query: 92 TVENISSSSTSEITPISKL----DEIEKSGTIPIAKPSETEQSETDCDVGEALDASAPIE 147 + ++ +SS +S+ + S D + S + + S++ S D ++ ++S Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805 Query: 148 QPSFVSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDNLK-N 206 DS + SS+ S +S+ G + N SD+ + Sbjct: 806 SSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSS 865 Query: 207 ESSDYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHATKKV 266 +SSD + + +S +S D + + + + S S ++S + S + Sbjct: 866 DSSDSSDSSNSSDSSDSS--DSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDS 923 Query: 267 QKNRNN 272 ++ N+ Sbjct: 924 SESSNS 929 >gi|114155142 nuclear pore complex-associated protein TPR [Homo sapiens] Length = 2363 Score = 41.6 bits (96), Expect = 0.005 Identities = 57/292 (19%), Positives = 115/292 (39%), Gaps = 28/292 (9%) Query: 707 ESVEYEAGHIPSPVIPQESSVEIDNET-EQKSESFSSIEKPSITYETNKVNELMDNIIKE 765 E +E E + + + V++ +T Q E E ++ ETNK+ +++ Sbjct: 1229 ELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQ 1288 Query: 766 DVNSMQIFTKLSETIVPPINTATVPDNE-----DGEAKMNIADTAK-----QTLISVVDS 815 D+ MQ + E + P+ A +E E K+ D + Q L+S Sbjct: 1289 DLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKD 1348 Query: 816 SSLPEVKE--EEQSPEDALLRGLQRTATDFYAELQNSTDLGYANGNLVHG--------SN 865 E ++ E+ ++ L AE+ S N NL+ Sbjct: 1349 PDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRT 1408 Query: 866 QKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAE 925 +KE++ L+ +I ++ + + ++++ +RY+ Q EE++ +K + +S + Sbjct: 1409 EKETIQKDLDAKIIDIQEKVKTITQ-VKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQ 1467 Query: 926 EQD------QRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLV 971 EQ Q E + + + ++ V NL T++E + E + Q V Sbjct: 1468 EQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTV 1519 Score = 37.7 bits (86), Expect = 0.067 Identities = 98/503 (19%), Positives = 186/503 (36%), Gaps = 104/503 (20%) Query: 485 ENATATAAPKMPE-STPVSTPVPSP-----EYVTTEVHTHDMEPSTPDTPKESPIVQLVQ 538 ++ + + PK P S VSTP P P E + + ++ + KE + +Q Sbjct: 634 DDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQ 693 Query: 539 EEEEEASPSTVTLLGSGEQEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVRVA 598 E+ E VT L S+ T I F+ Y+ V Sbjct: 694 NEQLEKLQEQVTDLR--------------------SQNTKISTQLDFASKRYEMLQDNVE 733 Query: 599 LYRQRSRTALSKGKDYLVLAQPPLLLPAESVDVSVLQPLSG--------ELENTNIEREA 650 YR+ + + + Q E + ++ Q L G E+ N+++E Sbjct: 734 GYRREITSLHERNQKLTATTQ-----KQEQIINTMTQDLRGANEKLAVAEVRAENLKKEK 788 Query: 651 ETVVLGDLSSSMHQDDLVNHTVDAVELEPSHSQTLSQSLLLDITPEINPLPKIEVSESVE 710 E + L ++ S ++ L+ ++ Q+LLL I + +E SE+ Sbjct: 789 EMLKLSEVRLSQQRESLL-------------AEQRGQNLLLTNLQTIQGI--LERSET-- 831 Query: 711 YEAGHIPSPVIPQESSVEIDNETEQKSESFSSIEKPSITYETNKVNELMDNIIKEDVNSM 770 E+ + ++ E+ S ++K + E + + L N+ DV + Sbjct: 832 -------------ETKQRLSSQIEKLEHEISHLKK-KLENEVEQRHTLTRNL---DVQLL 874 Query: 771 QIFTKLSETIVPPINTATVPDNEDGEAKMNIADTAKQTL----ISVVDSSSLPEVKEEEQ 826 +L +NT + N A+ IA T KQ L + V SS K + Sbjct: 875 DTKRQLDTETNLHLNTKELLKN----AQKEIA-TLKQHLSNMEVQVASQSSQRTGKGQPS 929 Query: 827 SPED-----ALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSNQKESVFMRLNNRIKAL 881 + ED + LR + D L+ ST SN ++ M + +L Sbjct: 930 NKEDVDDLVSQLRQTEEQVNDLKERLKTST------------SNVEQYQAM-----VTSL 972 Query: 882 EVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIQLLQAQ 941 E +++ + EE+ + +++E + + KL + +E + AI+ ++ Q Sbjct: 973 EESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQ 1032 Query: 942 LTNMTQLVSNLSATVAELKREVS 964 L+ + + +S++ V E + S Sbjct: 1033 LSELKKTLSSVQNEVQEALQRAS 1055 >gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens] Length = 1280 Score = 41.2 bits (95), Expect = 0.006 Identities = 33/179 (18%), Positives = 81/179 (45%), Gaps = 17/179 (9%) Query: 793 EDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTD 852 ++G + +++++ + V + + ++ + + A + ++RTA Q D Sbjct: 1054 QNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEED 1113 Query: 853 LGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNK 912 + NL + + + I L+ + +S R LEE +R Q ++MQK + Sbjct: 1114 VEETEQNLDEAKHAE-----KYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLE 1168 Query: 913 TIVKLQNT-SRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYL 970 +L+++ R+ +Q+++ ++ M ++S L A ELK++ ++ Q+ + Sbjct: 1169 YKARLEDSEERLRRQQEEKDSQ-----------MKSIISRLMAVEEELKKDHAEMQAVI 1216 >gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens] Length = 1139 Score = 41.2 bits (95), Expect = 0.006 Identities = 33/179 (18%), Positives = 81/179 (45%), Gaps = 17/179 (9%) Query: 793 EDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTD 852 ++G + +++++ + V + + ++ + + A + ++RTA Q D Sbjct: 913 QNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEED 972 Query: 853 LGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNK 912 + NL + + + I L+ + +S R LEE +R Q ++MQK + Sbjct: 973 VEETEQNLDEAKHAE-----KYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLE 1027 Query: 913 TIVKLQNT-SRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYL 970 +L+++ R+ +Q+++ ++ M ++S L A ELK++ ++ Q+ + Sbjct: 1028 YKARLEDSEERLRRQQEEKDSQ-----------MKSIISRLMAVEEELKKDHAEMQAVI 1075 >gi|133778961 testis expressed 15 [Homo sapiens] Length = 2789 Score = 40.4 bits (93), Expect = 0.010 Identities = 52/229 (22%), Positives = 82/229 (35%), Gaps = 52/229 (22%) Query: 63 SKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSSSTSEITP----ISKLDEIEKSGT 118 SKK S P + D ESS + +D + + + S + S P + E+ K+ Sbjct: 1329 SKKYSIPQLSAAAVTDSEGESSKSYLDKQRILTVDSFAASSTVPHCEQSCREKELLKTEQ 1388 Query: 119 IPIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSHGKGKITKS 178 T+ +ET+ LD ++ E+ D G++I +SSS Sbjct: 1389 CSSGNCLHTDGNETNVTENYELDVASGTEE-------DKSYGENIVELSSS--------- 1432 Query: 179 EFESKVSASEQGGGDPKSALNASDNLKNESSDYTKPGDIDPTSVASPKDPEDIPTFDEWK 238 S+L DN+K SS+ + KD ED T+ Sbjct: 1433 ----------------DSSLLLKDNVKGSSSE----------TCIVKKDTEDRITW---- 1462 Query: 239 KKVMEVEKEKSQSMHASSNGGSHATKKVQKNRNNYASVEC-GAKILAAN 286 KV + EK K S GS + + +N + C KI+ N Sbjct: 1463 -KVKQAEKAKDSVYKRSMTEGSTVNTEYKNQKNQISEESCLNEKIITTN 1510 Score = 33.5 bits (75), Expect = 1.3 Identities = 43/159 (27%), Positives = 67/159 (42%), Gaps = 17/159 (10%) Query: 1058 FSPEKKKKRCKYKIEK----IETIKPEEPLHPIANGDIKGRKPFTNQRDFSNMGEVYHSS 1113 ++ K KK + +I K I + P + I GRK +D S E + S Sbjct: 903 YNDTKNKKEVESRISKRKLHISSRDQNIPHKDLRRHKIYGRKRRLTSQDSS---ECFSSL 959 Query: 1114 YKGPPSEGSSETSSQSEE---SYFCGISACTSLCNGQSQKTKTEKRA--LKRRRSKVQDQ 1168 S+G +T SQSE+ S +S SLC + K +K LK+ +V Sbjct: 960 -----SQGRIKTFSQSEKHIKSVLNILSDEASLCKSKCLSRKLDKAVVHLKKAHRRVHTS 1014 Query: 1169 GKLIKTLIQTKSGSLPSLHDIIKGNKEITVGTFGVTAVS 1207 +LI + + + G LP + II N + G ++VS Sbjct: 1015 LQLITKVGEERKGPLPKSYAIICNNFWESCDLQGYSSVS 1053 >gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] Length = 1411 Score = 40.0 bits (92), Expect = 0.013 Identities = 118/595 (19%), Positives = 224/595 (37%), Gaps = 77/595 (12%) Query: 623 LLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMH--QDDLVNHTVDAVELEPS 680 LL ++S+L+ +L E ET VL L H Q+ + T S Sbjct: 531 LLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSES 590 Query: 681 HSQTLSQSLLLDITPEINPLPKIEVSE--SVEYEAGHIPSPVIPQESSV-EIDNETEQKS 737 H Q +Q L D E + S+E + S + + V ++D + + K+ Sbjct: 591 HKQ--AQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKT 648 Query: 738 ESFSSIEKPSITY--------------------ETNKVNELMDNIIKE----DVNSMQIF 773 E S E E NK+ +D + + + Q+ Sbjct: 649 ELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLE 708 Query: 774 TKLSETIVPPINTATVPDNEDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALL 833 + L E ++ + +G+ K AD+ + + +L +++++ Q D L Sbjct: 709 SHLKEYKEKYLSLEQKTEELEGQIKKLEADSLE---VKASKEQALQDLQQQRQLNTDLEL 765 Query: 834 RGLQRTAT-DFYAELQNSTDLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYL 892 R + + + E+ +ST L +L S ES+ +L + E + + Sbjct: 766 RATELSKQLEMEKEIVSSTRL-----DLQKKSEALESIKQKLTKQ----EEEKQILKQDF 816 Query: 893 EELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNL 952 E LSQ + Q EE+ T+ +LQ ++ E++ TE L ++++ +L Sbjct: 817 ETLSQETKIQHEELNNRIQTTVTELQ---KVKMEKEALMTE----LSTVKDKLSKVSDSL 869 Query: 953 SATVAELKREVSDRQSYLVISLVLCVVLGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSP 1012 + +E ++E ++ ++ C L L +Q NT + + L K + Sbjct: 870 KNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQ-MENTLKEQKELKKSLEKEKEASHQ 928 Query: 1013 -KRCFSSYDDMNLKRRTSFPLMRSKSLQLTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKI 1071 K +S + ++ + + + QL G + LK S E+KKK Sbjct: 929 LKLELNSMQEQLIQAQNTLKQNEKEEQQLQGN---------INELKQSSEQKKK------ 973 Query: 1072 EKIETIKPEEPLHPIANGDIKGR-KPFTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSE 1130 +IE ++ E + + +++ + + Q E S E S ET Q + Sbjct: 974 -QIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQ 1032 Query: 1131 ESYFCGISACTSLCNGQSQKTKTEKRALKR-----RRSKVQDQGKLIKTLIQTKS 1180 ++ S L Q K+ EK +L + R+++ +Q KLI+ L K+ Sbjct: 1033 SDFYGRESEL--LATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKA 1085 Score = 36.6 bits (83), Expect = 0.15 Identities = 58/325 (17%), Positives = 125/325 (38%), Gaps = 35/325 (10%) Query: 676 ELEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEI-DNETE 734 EL+ S Q Q L +I L K E+ ++ + + ++ + + N E Sbjct: 963 ELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYE 1022 Query: 735 QKSESFSSIEKPSITYETNKVNELMD--------NIIKEDVNSMQIFTKLSETIVPPINT 786 + E+F ++ E+ + D ++ +ED+ S + ++ + T Sbjct: 1023 KSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKT 1082 Query: 787 ATVPDNEDGEAKMN--------IADTAKQTLIS----VVDSSSLPEVKEEEQSPEDALLR 834 A +D K + D K+ + V + S L E++E + E + + Sbjct: 1083 AKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITK 1142 Query: 835 GLQRTATDFYAELQNSTDLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEE 894 + + ++ T+L A L+ QK + L + +L+ + R + Sbjct: 1143 LNEELKSHKLESIKEITNLKDAKQLLIQ---QK----LELQGKADSLKAAVEQEKRNQQI 1195 Query: 895 LSQRYRKQMEEMQKAFNKTIVKLQNT-------SRIAEEQDQRQTEAIQLLQAQLTNMTQ 947 L + +K+ EE++K F + KL + + EE + + T I L L + + Sbjct: 1196 LKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKK 1255 Query: 948 LVSNLSATVAELKREVSDRQSYLVI 972 + V+EL+++ D + + + Sbjct: 1256 EWQSSQRRVSELEKQTDDLRGEIAV 1280 Score = 31.2 bits (69), Expect = 6.2 Identities = 49/247 (19%), Positives = 92/247 (37%), Gaps = 34/247 (13%) Query: 751 ETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGEAKMNIADTAKQTLI 810 E +V LMDN+ E + KL + + + + + +A ++ + Sbjct: 229 ELVQVQTLMDNMTLERERESE---KLKDECKKLQSQYASSEATISQLRSELAKGPQEVAV 285 Query: 811 SVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSNQKESV 870 V + L E L L + D+ + + + N+ +QK+ Sbjct: 286 YVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLD 345 Query: 871 FMRLNNRIKALE-------VNMSLSG----RYLEELS----------------QRYRKQM 903 +L +R+ A E V +S G + EELS Q+ R++ Sbjct: 346 CQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEK 405 Query: 904 E----EMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAEL 959 E ++Q N+ KL T R E R E QL +L + Q V++L ++ L Sbjct: 406 EQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRL 465 Query: 960 KREVSDR 966 + ++ ++ Sbjct: 466 EEQLKEK 472 >gi|109255236 centrosomal protein 63 isoform d [Homo sapiens] Length = 475 Score = 40.0 bits (92), Expect = 0.013 Identities = 37/160 (23%), Positives = 73/160 (45%), Gaps = 22/160 (13%) Query: 822 KEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSN-QKESVFMRLNNRIKA 880 KEE+ + LL LQ + A LQ+ NL+H + QKE +L ++KA Sbjct: 251 KEEKLRESEKLLEALQEEKRELKAALQSQE-------NLIHEARIQKE----KLQEKVKA 299 Query: 881 LEVNMSLSGRYLE-------ELSQRYRKQMEEMQKAF---NKTIVKLQNTSRIAEEQDQR 930 ++ LE +LSQ ++ EE+++ N+ +++ + +Q Sbjct: 300 TNTQHAVEAISLESVSATCKQLSQELMEKYEELKRMEAHNNEYKAEIKKLKEQILQGEQS 359 Query: 931 QTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYL 970 + A++ ++ +++++TQ + T+A K SD + L Sbjct: 360 YSSALEGMKMEISHLTQELHQRDITIASTKGSSSDMEKRL 399 >gi|109255226 centrosomal protein 63 isoform c [Homo sapiens] Length = 495 Score = 40.0 bits (92), Expect = 0.013 Identities = 37/160 (23%), Positives = 73/160 (45%), Gaps = 22/160 (13%) Query: 822 KEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSN-QKESVFMRLNNRIKA 880 KEE+ + LL LQ + A LQ+ NL+H + QKE +L ++KA Sbjct: 251 KEEKLRESEKLLEALQEEKRELKAALQSQE-------NLIHEARIQKE----KLQEKVKA 299 Query: 881 LEVNMSLSGRYLE-------ELSQRYRKQMEEMQKAF---NKTIVKLQNTSRIAEEQDQR 930 ++ LE +LSQ ++ EE+++ N+ +++ + +Q Sbjct: 300 TNTQHAVEAISLESVSATCKQLSQELMEKYEELKRMEAHNNEYKAEIKKLKEQILQGEQS 359 Query: 931 QTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYL 970 + A++ ++ +++++TQ + T+A K SD + L Sbjct: 360 YSSALEGMKMEISHLTQELHQRDITIASTKGSSSDMEKRL 399 >gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 [Homo sapiens] Length = 3259 Score = 40.0 bits (92), Expect = 0.013 Identities = 38/170 (22%), Positives = 76/170 (44%), Gaps = 7/170 (4%) Query: 798 KMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYAN 857 K+ + DT + + + SSLP V++E+ S E + + D EL+++ G + Sbjct: 612 KVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKS 671 Query: 858 GNLVHGSNQ-KESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK 916 + V Q + RL ++I LE+N + E+ K++ + + + Sbjct: 672 LSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKN 731 Query: 917 LQNTS----RIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKRE 962 N S ++EE+DQ ++ +L + +T + V L +AE +R+ Sbjct: 732 ADNNSSAFTALSEERDQLLSQVKEL--SMVTELRAQVKQLEMNLAEAERQ 779 Score = 36.2 bits (82), Expect = 0.19 Identities = 45/230 (19%), Positives = 93/230 (40%), Gaps = 26/230 (11%) Query: 751 ETNKVNELMDNIIKEDVNSMQIFTKLSE------TIVPPINTATVPDNEDGEAKMNIADT 804 E + +N+L++ K N+ FT LSE + V ++ T + + +MN+A+ Sbjct: 717 EISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEA 776 Query: 805 AKQTLISVVDSSSLPEVKEE-------EQSPEDALLRGLQRTATDFYAELQNSTDLGYAN 857 +Q + ++ + E E +D + LQ D + + L Sbjct: 777 ERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTL---I 833 Query: 858 GNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVK- 916 +L KES + R++ + +EELSQ ++ E+ K + K Sbjct: 834 RSLQSQLQNKESEVLEGAERVRHISSK-------VEELSQALSQKELEITKMDQLLLEKK 886 Query: 917 --LQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVS 964 ++ + EE+DQ+ TE + ++ + + +L + LK +++ Sbjct: 887 RDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLN 936 Score = 32.0 bits (71), Expect = 3.7 Identities = 21/88 (23%), Positives = 47/88 (53%), Gaps = 10/88 (11%) Query: 890 RYLEELSQ------RYRKQMEEMQKAFNKTI----VKLQNTSRIAEEQDQRQTEAIQLLQ 939 +Y E+L+Q +KQ+ E+Q NK + KL+ + +EE ++ + LQ Sbjct: 2535 QYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQ 2594 Query: 940 AQLTNMTQLVSNLSATVAELKREVSDRQ 967 + ++++ + +L ++++L R+V+ Q Sbjct: 2595 EEKQDLSKEIESLKVSISQLTRQVTALQ 2622 Score = 31.2 bits (69), Expect = 6.2 Identities = 33/156 (21%), Positives = 68/156 (43%), Gaps = 8/156 (5%) Query: 806 KQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSN 865 K+ L+ ++S ++ E + E + LQ+ +N ++ ++V Sbjct: 1583 KEKLVKEIESLKSSKIAESTEWQEKH--KELQKEYEILLQSYENVSNEAERIQHVVEAVR 1640 Query: 866 QKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAE 925 Q++ L ++++ E N + + L+E Q + E+M+K F K+ K Q + E Sbjct: 1641 QEKQ---ELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRK-FAKS--KQQKILELEE 1694 Query: 926 EQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKR 961 E D+ + E M L+S+ ++ EL+R Sbjct: 1695 ENDRLRAEVHPAGDTAKECMETLLSSNASMKEELER 1730 >gi|242117996 hypothetical protein LOC392307 [Homo sapiens] Length = 402 Score = 39.7 bits (91), Expect = 0.018 Identities = 39/137 (28%), Positives = 57/137 (41%), Gaps = 21/137 (15%) Query: 474 EDLTEGNKSISENATATAAPKMPESTPVSTPVPSPEYVTTEVHTHD--MEPSTPDTPKES 531 EDL E + S S +T+ + T S VPSP + E H+ + EPS +TP E+ Sbjct: 28 EDLQENHISESFLKPSTSETPLEPHTSESPLVPSPSQIPLEAHSPETHQEPSISETPSET 87 Query: 532 PI--------VQLVQEEEEEASPST--VTLLGSGE--QEDESS-------PWFESETQIF 572 P + +V E+ P + L S + +ED SS PW T + Sbjct: 88 PTYEASLDSPISVVPEKHLTLPPQSRDYVCLSSSDTLKEDLSSESSSNEVPWTRRSTHLS 147 Query: 573 CSELTTICCISSFSEYI 589 SE C+S S + Sbjct: 148 ESESLPEHCLSGPSSQV 164 >gi|109255234 centrosomal protein 290kDa [Homo sapiens] Length = 2479 Score = 39.7 bits (91), Expect = 0.018 Identities = 74/368 (20%), Positives = 156/368 (42%), Gaps = 35/368 (9%) Query: 612 KDYLVLAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNH- 670 KD +++ + L E ++S L ++E+ N E E L + + Q+ + + Sbjct: 982 KDNMLVQRTSNLEHLECENIS----LKEQVESINKELEITKEKLHTIEQAWEQETKLGNE 1037 Query: 671 -TVDAVELEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEI 729 ++D + ++S +S S + + E+ L + + +E + H+ + + E E Sbjct: 1038 SSMDKAKKSITNSDIVSISKKITML-EMKELNERQRAEHCQKMYEHLRTSLKQME---ER 1093 Query: 730 DNETEQKSESFSSIEKPSITYETNKVNELMDNIIK--EDVNSMQIFTKLSETIVPPINTA 787 + E E K + I + E +EL D++ K D + +I + + + Sbjct: 1094 NFELETKFAELTKINLDAQKVEQMLRDELADSVSKAVSDADRQRILELEKNEMELKVEVS 1153 Query: 788 TVPDNED-GEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAE 846 + + D ++ I + +Q+ V+S + + + QS E +L+ L + + Sbjct: 1154 KLREISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKLHQHNVSL--Q 1211 Query: 847 LQNSTDLGYANGNLVHGSNQKESVFMRLNNRIKALEVNM---SLSGR----YLEELSQRY 899 L +T LG ++ + E+ +RL ++ E + L GR +L + Q Sbjct: 1212 LSEATALGKLE-SITSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSL 1270 Query: 900 RKQME-----EMQKAFNKTIVKLQNTS-RIAEEQDQRQTEAIQL------LQAQLTNMTQ 947 R+Q Q+ F+KT+++LQN +I +E Q E + ++ +L + + Sbjct: 1271 RRQFSGALPLAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEE 1330 Query: 948 LVSNLSAT 955 L+S L T Sbjct: 1331 LISTLKDT 1338 >gi|51988900 XPG-complementing protein [Homo sapiens] Length = 1186 Score = 39.7 bits (91), Expect = 0.018 Identities = 60/254 (23%), Positives = 103/254 (40%), Gaps = 45/254 (17%) Query: 40 YYSQDDNCALENEDVQFQKKNTESKKLSPPVVETLPTVDLHEESSNAVVDSETV---ENI 96 Y S+ D+ L ++D K N+ S+ + P V L E SS V SE V EN+ Sbjct: 552 YESKFDSSLLSSDDETKCKPNSASEVIGP--------VSLQETSSIVSVPSEAVDNVENV 603 Query: 97 SSSSTSE----ITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDASAPIEQPSFV 152 S + E + I + E +G I+ P E E D + E+ D S IE S + Sbjct: 604 VSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESES-DGSF-IEVQSVI 661 Query: 153 SPPDSLVGQHIENVSSSHGKGKITKSEF-ESKVSASEQGGGDPKSALNASDNLKNES--S 209 S + ++EF E+ SEQG + ++ES Sbjct: 662 SDEE-------------------LQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLR 702 Query: 210 DYTKPGDIDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHASSNGGSHATKKVQKN 269 D ++ D+D + KD ED + EW+ ++ E+ +++ ++ ++ K ++ Sbjct: 703 DNSERDDVDGEPQEAEKDAED--SLHEWQ----DINLEELETLESNLLAQQNSLKAQKQQ 756 Query: 270 RNNYASVECGAKIL 283 + A+ G L Sbjct: 757 QERIAATVTGQMFL 770 >gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo sapiens] Length = 1133 Score = 39.7 bits (91), Expect = 0.018 Identities = 70/331 (21%), Positives = 143/331 (43%), Gaps = 29/331 (8%) Query: 732 ETEQKSESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPD 791 +TE K ++ SS + E NKV + + +I+E +++ T + E + + + Sbjct: 513 KTEDKLQAASS----QLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMY-----SVTKE 563 Query: 792 NEDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNST 851 +D + K+ + L+S V+ ++ E +D L L + + +++T Sbjct: 564 RDDLKNKLKAEEEKGNDLLSRVNMLK-NRLQSLEAIEKDFLKNKLNQDSG------KSTT 616 Query: 852 DLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFN 911 L N + S + E + ++L + +KA+E ++ + E L +RY + ++ Q + Sbjct: 617 ALHQENNKIKELSQEVERLKLKLKD-MKAIEDDLMKTEDEYETLERRYANERDKAQ-FLS 674 Query: 912 KTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLV 971 K + ++ + ++ +T Q L +L +LS V LK ++ + Y+ Sbjct: 675 KELEHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDALKEKIHE---YMA 731 Query: 972 ISLVLCVVLG----LMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLK-R 1026 ++C + G L + + N ++ G I L K + R FS +L R Sbjct: 732 TEDLICHLQGDHSVLQKKLNQQENRNRDLGREIENLTKELE---RYRHFSKSLRPSLNGR 788 Query: 1027 RTSFPLMRSKSLQLTGKEVDPNDLYIVEPLK 1057 R S P + SK +Q + +P D + PL+ Sbjct: 789 RISDPQVFSKEVQTEAVDNEPPDYKSLIPLE 819 >gi|109659849 filamin A interacting protein 1-like isoform 2 [Homo sapiens] Length = 893 Score = 39.7 bits (91), Expect = 0.018 Identities = 70/331 (21%), Positives = 143/331 (43%), Gaps = 29/331 (8%) Query: 732 ETEQKSESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPD 791 +TE K ++ SS + E NKV + + +I+E +++ T + E + + + Sbjct: 273 KTEDKLQAASS----QLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMY-----SVTKE 323 Query: 792 NEDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNST 851 +D + K+ + L+S V+ ++ E +D L L + + +++T Sbjct: 324 RDDLKNKLKAEEEKGNDLLSRVNMLK-NRLQSLEAIEKDFLKNKLNQDSG------KSTT 376 Query: 852 DLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFN 911 L N + S + E + ++L + +KA+E ++ + E L +RY + ++ Q + Sbjct: 377 ALHQENNKIKELSQEVERLKLKLKD-MKAIEDDLMKTEDEYETLERRYANERDKAQ-FLS 434 Query: 912 KTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLV 971 K + ++ + ++ +T Q L +L +LS V LK ++ + Y+ Sbjct: 435 KELEHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDALKEKIHE---YMA 491 Query: 972 ISLVLCVVLG----LMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLK-R 1026 ++C + G L + + N ++ G I L K + R FS +L R Sbjct: 492 TEDLICHLQGDHSVLQKKLNQQENRNRDLGREIENLTKELE---RYRHFSKSLRPSLNGR 548 Query: 1027 RTSFPLMRSKSLQLTGKEVDPNDLYIVEPLK 1057 R S P + SK +Q + +P D + PL+ Sbjct: 549 RISDPQVFSKEVQTEAVDNEPPDYKSLIPLE 579 >gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo sapiens] Length = 1135 Score = 39.7 bits (91), Expect = 0.018 Identities = 70/331 (21%), Positives = 143/331 (43%), Gaps = 29/331 (8%) Query: 732 ETEQKSESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPD 791 +TE K ++ SS + E NKV + + +I+E +++ T + E + + + Sbjct: 513 KTEDKLQAASS----QLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMY-----SVTKE 563 Query: 792 NEDGEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNST 851 +D + K+ + L+S V+ ++ E +D L L + + +++T Sbjct: 564 RDDLKNKLKAEEEKGNDLLSRVNMLK-NRLQSLEAIEKDFLKNKLNQDSG------KSTT 616 Query: 852 DLGYANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFN 911 L N + S + E + ++L + +KA+E ++ + E L +RY + ++ Q + Sbjct: 617 ALHQENNKIKELSQEVERLKLKLKD-MKAIEDDLMKTEDEYETLERRYANERDKAQ-FLS 674 Query: 912 KTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLV 971 K + ++ + ++ +T Q L +L +LS V LK ++ + Y+ Sbjct: 675 KELEHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDALKEKIHE---YMA 731 Query: 972 ISLVLCVVLG----LMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLK-R 1026 ++C + G L + + N ++ G I L K + R FS +L R Sbjct: 732 TEDLICHLQGDHSVLQKKLNQQENRNRDLGREIENLTKELE---RYRHFSKSLRPSLNGR 788 Query: 1027 RTSFPLMRSKSLQLTGKEVDPNDLYIVEPLK 1057 R S P + SK +Q + +P D + PL+ Sbjct: 789 RISDPQVFSKEVQTEAVDNEPPDYKSLIPLE 819 >gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax homolog 2 [Homo sapiens] Length = 1210 Score = 39.3 bits (90), Expect = 0.023 Identities = 58/279 (20%), Positives = 100/279 (35%), Gaps = 21/279 (7%) Query: 32 SSSASASSYYSQDDNCALENEDVQFQK--KNTESKKLSPPVVETLPTVDLHEESSNAVVD 89 S+S +S +DD ++ED ++ + S P ++LP SS+A + Sbjct: 413 SNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESE 472 Query: 90 SETVENISSSSTSEITPISKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDASAPIEQP 149 S + + SS S SE + + P +P T + + D + + +AP E P Sbjct: 473 STSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGP 532 Query: 150 SFVSPP---DSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDNLKN 206 PP G S H + K + SK + P + Sbjct: 533 RSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQ 592 Query: 207 ESSDYTKPGDIDP-------------TSVASPKDPEDIP--TFDEWKKKVMEVEKEKSQS 251 E G P TS+ ++P +P + D+ K +V K K + Sbjct: 593 EPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKV-KTKGRP 651 Query: 252 MHASSNGGSHATKKVQKNRNNYASVECGAKILAANPEAK 290 A+SN A + + + +S+ +K L+ AK Sbjct: 652 RAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAK 690 Score = 35.8 bits (81), Expect = 0.25 Identities = 44/206 (21%), Positives = 81/206 (39%), Gaps = 32/206 (15%) Query: 361 FHGRDERNVQSFPLDEQMYAKYVKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQ 420 F +D ++V S +++ Y K S G+ +SM+E+ +++DS+ Sbjct: 387 FPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGT-------------SSMLEDDLQLSDSE 433 Query: 421 YHSERQELFDEDYDYPLDYNTGEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGN 480 Q T E S + SA ++ V +A+ A++E ++ + Sbjct: 434 DSDSEQ--------------TPEKPPSSSAPPSAPQSLPEPV-ASAHSSSAESESTSDSD 478 Query: 481 KSISENATATAAPKMPESTPVSTPVPSPEYVTTEVHTHD---MEPSTPDTPKESPIVQLV 537 S S++ + +++ E+ P+ TP P PE TT D + S P P E P Sbjct: 479 SS-SDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEP 537 Query: 538 QEEEEEASPSTVTLLGSGEQEDESSP 563 E+ S+ + E + P Sbjct: 538 PRRHPESKGSSDSATSQEHSESKDPP 563 >gi|14165274 golgi-associated microtubule-binding protein HOOK3 [Homo sapiens] Length = 718 Score = 39.3 bits (90), Expect = 0.023 Identities = 65/324 (20%), Positives = 136/324 (41%), Gaps = 35/324 (10%) Query: 728 EIDNETEQKSESFSSI--EKPSITYETNKVNELMDNIIKEDVNSMQIFTK---------- 775 ++D E ++ E S+ EK + E + + E ++ + Q+ T+ Sbjct: 391 KLDFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQES 450 Query: 776 ----LSETIVPPINTATVP-DNEDGEAKMNI--ADTAKQTLI-SVVDSSSLP--EVKEEE 825 +E + P I + +E+ K+N +D K L+ S++D ++L E++ E Sbjct: 451 SDSLAAEIVTPEIREKLIRLQHENKMLKLNQEGSDNEKIALLQSLLDDANLRKNELETEN 510 Query: 826 QSPEDALLR------GLQRTATDFYAELQNSTDLGYANGNLVHGSNQKESVFMRLNNRIK 879 + LL LQ++ D ++ ++S L + ++ + + I+ Sbjct: 511 RLVNQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKLEEHLEKLHEANNELQKKRAIIE 570 Query: 880 ALEVNMSLSGRYLEELSQRYRK---QMEEMQKAFNKTIVKLQNTSRIAE-EQDQRQTEAI 935 LE + S +EEL + RK +M++M++ + K + K ++ R + +Q+Q I Sbjct: 571 DLEPRFNNSSLKIEELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQGAAPEI 630 Query: 936 QLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVISLVLCVVLGLMLCMQRCRNTSQF 995 Q L+ QL +L +L + K + + Y+V + +G+ L + + Sbjct: 631 QALKNQLQERDRLFHSLEKEYEKTKSQREMEEKYIVSA---WYNMGMTLHKKAAEDRLAS 687 Query: 996 DGDYISKLPKSNQYPSPKRCFSSY 1019 G S L + Q S +R + + Sbjct: 688 TGSGQSFLARQRQATSSRRSYPGH 711 >gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] Length = 1684 Score = 38.9 bits (89), Expect = 0.030 Identities = 69/365 (18%), Positives = 140/365 (38%), Gaps = 36/365 (9%) Query: 628 SVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVE-LEPS-HSQTL 685 S D + LQ E NT +E + L + +D V + +E + P Q L Sbjct: 146 SEDKANLQKQLEEAMNTQLELSEQ------LKFQNNSEDNVKKLQEEIEKIRPGFEEQIL 199 Query: 686 SQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIP-QESSVEIDN-ETEQKSESFSSI 743 LD T + ++ +E + H + QE +++ E+ E I Sbjct: 200 YLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQI 259 Query: 744 EKPSITYET--NKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDGE----- 796 E + +E NK+NEL +N++K+ S + K E + + AT N+D + Sbjct: 260 EASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQDNQICSIL 319 Query: 797 ------AKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAE-LQN 849 + + + K ++ + S + ++E + + L L+ A E Sbjct: 320 LQENTFVEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHE 379 Query: 850 STDLGYANGNLVHGSNQKESVFMRLNNRIKALE----VNMSLSGRYLEELSQRYRKQMEE 905 DL + L+ ++ V +L + + L + R ++ L ++++K++ E Sbjct: 380 REDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISE 439 Query: 906 MQKAFNK--------TIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVA 957 + + F + ++Q E Q + EAI ++ M L + L + Sbjct: 440 LNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQTELGESAG 499 Query: 958 ELKRE 962 ++ +E Sbjct: 500 KISQE 504 Score = 32.0 bits (71), Expect = 3.7 Identities = 72/387 (18%), Positives = 149/387 (38%), Gaps = 26/387 (6%) Query: 607 ALSKGKDYLVLAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDD 666 +L KD L + L+ AES ++L + E ++E+E + Q Sbjct: 997 SLRSEKDQLSASMRDLIQGAESYK-NLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQ-- 1053 Query: 667 LVNHTVDAVELEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESS 726 L N T+ + + L++ L ++ + +EV + + + + +E Sbjct: 1054 LRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQK 1113 Query: 727 VEIDNETEQKSESFSSIEKPSITYETNKVNELMDNI--IKEDVNS---MQIFTKLSETIV 781 ++ T + E + + E ++ + M + +K+D M + E ++ Sbjct: 1114 IKEHATTVNELEEL----QVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLM 1169 Query: 782 PPINTATVPDN---EDGEAKMNIADTAKQTLISVVDS--SSLPEVKEEEQSPEDALLRGL 836 +N N ED E ++ I ++TL + S SS+ + +E+ + L++ Sbjct: 1170 KELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTK 1229 Query: 837 QRTATDFYAELQNSTDLGYANGNLVHGSNQKESVFMRL------NNRI-KALEVNMSLSG 889 + A AE + G L Q E ++L ++I + L+ + Sbjct: 1230 KELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQ 1289 Query: 890 RYLEELSQRYRKQMEEMQ--KAFNKTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQ 947 R L QR EE + KA T+ + ++ +Q + + QA+ Q Sbjct: 1290 RTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQ 1349 Query: 948 LVSNLSATVAELKREVSDRQSYLVISL 974 +L + +LK ++ D Q+ L I++ Sbjct: 1350 EREHLEMLIDQLKIKLQDSQNNLQINV 1376 >gi|213385278 TNF receptor-associated factor 3 interacting protein 1 isoform 2 [Homo sapiens] Length = 625 Score = 38.9 bits (89), Expect = 0.030 Identities = 54/264 (20%), Positives = 110/264 (41%), Gaps = 32/264 (12%) Query: 724 ESSVEIDNETEQKSESFSSIEKPSITYETNKV-NELMDNIIK-----------------E 765 ++SVE D+ ++ + ++ + + S ET ++ NEL NI + + Sbjct: 350 KNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQD 409 Query: 766 DVNSMQIFTKLSETIVPPINTATVPDNEDGEAKMNIADTAKQTLISVVDSSSLPEVKEEE 825 + ++Q+ S V N T N D E A L + + + V+ EE Sbjct: 410 SMEALQMDRSGSGKTVS--NVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEE 467 Query: 826 QSPEDALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSNQKESVFM-----RLNNRIKA 880 + L++ + T D Y +LQ S G +L + +KE + +L I+ Sbjct: 468 EEKHGGLVKKILETKKD-YEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTSIQT 526 Query: 881 LEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTE-AIQLLQ 939 L + G+ ++ + + E+Q ++ + A +Q+QR T+ A++ L+ Sbjct: 527 LCKSALPLGKIMDYIQEDVDAMQNELQMWHSENRQHAE-----ALQQEQRITDCAVEPLK 581 Query: 940 AQLTNMTQLVSNLSATVAELKREV 963 A+L + QL+ + + +K + Sbjct: 582 AELAELEQLIKDQQDKICAVKANI 605 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 38.9 bits (89), Expect = 0.030 Identities = 73/345 (21%), Positives = 129/345 (37%), Gaps = 38/345 (11%) Query: 453 SATNAILNMVNIAANILGAKTEDLTEGNKSISENATA--TAAPKMPESTPVSTPVPSPEY 510 S T + +N + L +T +++ S TA T+ P P + STP+ S Sbjct: 1934 STTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPT-PAYSEGSTPLTSMPL 1992 Query: 511 VTTEVHTHDMEPSTPDTPKESPIVQLVQEEEEEASPSTVTLLGSGEQEDESSPWFESETQ 570 TT V + E ST T E +SP+T +G ++S E T Sbjct: 1993 STTLVVSS--EASTLSTTPVDTSTPATTSTEGSSSPTT-----AGGTSIQTSTPSERTTP 2045 Query: 571 IFCSELTTICCISSFSEYIYKW---CSVRVALYRQRSRTALSKGKDYLVLAQP---PLLL 624 + ++T +SS + +V + S +A ++G + A PLL Sbjct: 2046 LAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLT 2105 Query: 625 PAESVDVSVLQPLSGELENTNIEREAETVVLGDLSSSMHQDDLVNHTVDAVELEPSHSQT 684 V P + L T ++ + + ++SSS + E + QT Sbjct: 2106 SIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSS------------PIPTEGTSMQT 2153 Query: 685 LSQSLLLDITPEINPLPKIEVSESVEYEAGHIPSPVIPQESSVEIDNETEQKSESFSSIE 744 + S PL + VS +V + P ++S + N TE +S +S Sbjct: 2154 STYS------DRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTS-- 2205 Query: 745 KPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETI-VPPINTAT 788 + T+ +E V++M + T + T+ P++T+T Sbjct: 2206 -EGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTST 2249 Score = 34.3 bits (77), Expect = 0.74 Identities = 60/279 (21%), Positives = 101/279 (36%), Gaps = 32/279 (11%) Query: 42 SQDDNCALENEDVQFQKKNTESKKLSPPVVE--TLPTVDLHEES--------SNAVVDSE 91 S+ N + D + Q + SPP E ++PT E S S V S Sbjct: 467 SEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASS 526 Query: 92 TVENISSSSTSEITPISKLDEIEKSGT------IPIAKPSETEQSETDCDVGEALDASAP 145 +S++ TP++ E S T IP + PSE T+ V L S+ Sbjct: 527 EASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSE 586 Query: 146 IEQPSFVSPPDSLVGQHIENVSSSHGKGKITKSEFESKVSASEQGGGDPKSALNASDNL- 204 S +P DS + +SS T +E S +++ G ++++ S L Sbjct: 587 ASTTS-TTPADS----NTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLV 641 Query: 205 --KNESSDYTKPGD--------IDPTSVASPKDPEDIPTFDEWKKKVMEVEKEKSQSMHA 254 S+ T P D + TS ++ + +PT + + ++ A Sbjct: 642 ASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVA 701 Query: 255 SSNGGSHATKKVQKNRNNYASVECGAKILAANPEAKSTS 293 SS + +T V + S E + A+ + TS Sbjct: 702 SSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTS 740 Score = 33.9 bits (76), Expect = 0.96 Identities = 36/154 (23%), Positives = 57/154 (37%), Gaps = 21/154 (13%) Query: 60 NTESKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSSSTSEITPI------------ 107 N+E+ LS V+T V E+S++ +E S+ + TP+ Sbjct: 2706 NSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVAS 2765 Query: 108 ---SKLDEIEKSGTIPIAKPSETEQSETDCDVGEALDASAPIEQPSFVSPP-DSLVGQHI 163 S + +IP+ +E S T +V S P PS S P S+ H Sbjct: 2766 SEASTVSTTAVDTSIPVTTSTEASSSPTTAEV-----TSMPTSTPSETSTPLTSMPVNHT 2820 Query: 164 ENVSSSHGKGKITKSEFESKVSASEQGGGDPKSA 197 SS G T + + V+ S + P +A Sbjct: 2821 PVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTA 2854 Score = 33.5 bits (75), Expect = 1.3 Identities = 35/148 (23%), Positives = 59/148 (39%), Gaps = 11/148 (7%) Query: 61 TESKKLSPPVVETLPTVDLHEESSNAVVDSETVENISSSSTSEITPISKL---------D 111 +E LS V+T V E S+ +E ++S+ + TP++ + Sbjct: 349 SEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASS 408 Query: 112 EIEKSGTIPI-AKPSETEQSETDCDVGEALDASAPIEQPSFVSPPDSLVGQHIENVSSSH 170 E + TIP+ +K T SE A D S PS S P + + V+SS Sbjct: 409 EASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSE 468 Query: 171 GKG-KITKSEFESKVSASEQGGGDPKSA 197 T + +++V+ S + P +A Sbjct: 469 ASNLSTTPVDSKTQVTTSTEASSSPPTA 496 Score = 32.0 bits (71), Expect = 3.7 Identities = 65/315 (20%), Positives = 111/315 (35%), Gaps = 28/315 (8%) Query: 477 TEGNKSISENATATAAPKMPESTPVSTPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQL 536 TEG+ S T MP STP P + + V E ST T + Sbjct: 2904 TEGSSS----PTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPV 2959 Query: 537 VQEEEEEASPSTVTLLGSGEQEDESSPWFESETQIFCSELTTICCISSFSEYIYKWCSVR 596 E +SP+T G S+P E T + ++T+ SS + Sbjct: 2960 TTSAEASSSPTT----AEGTSMPISTPG-ERRTPLTSMSVSTMPVASSEAS--------- 3005 Query: 597 VALYRQRSRTALSKGKDYLVLAQPPLLLPAESVDVSVLQPLSGELENTNIEREAETVVLG 656 L R + T+ + P AE + + P G T+I V + Sbjct: 3006 -TLSRTPADTSTPVTTSTEASSSP---TTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIP 3061 Query: 657 DLSS-SMHQDDLVNHTVDAVELEPSHSQTLSQSLLLDITPE-INPLPKIEVSESVEYEAG 714 + S+ S D + V + E+ S + S+ + E PL + VS + + Sbjct: 3062 EASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSA 3121 Query: 715 HIPSPVIPQESSVEIDNETEQKSESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFT 774 P ++S + TE S +S + T+ +E + V++M + + Sbjct: 3122 ISTLSTTPVDTSTPVTTSTEAHSSPTTS---EGTSMPTSTPSEGSTPLTYMPVSTMLVVS 3178 Query: 775 KLSETI-VPPINTAT 788 T+ P++T+T Sbjct: 3179 SEDSTLSATPVDTST 3193 Score = 31.2 bits (69), Expect = 6.2 Identities = 24/109 (22%), Positives = 47/109 (43%), Gaps = 15/109 (13%) Query: 455 TNAILNMVNIAANILGAKTEDLTEGNKSISENATATAAPK------MPESTP------VS 502 TN ++ +A++ + + N ++ ++ A+++P M STP ++ Sbjct: 3520 TNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLT 3579 Query: 503 TPVPSPEYVTTEVHTHDMEPSTPDTPKESPIVQLVQEEEEEASPSTVTL 551 T + S YVT+ + PSTP + +P+ Q P +TL Sbjct: 3580 TMLLSSTYVTS---SEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITL 3625 >gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] Length = 3907 Score = 38.5 bits (88), Expect = 0.039 Identities = 74/361 (20%), Positives = 137/361 (37%), Gaps = 46/361 (12%) Query: 649 EAETVVLGDLSSSMHQDDLVNHTVDAVELEPSHSQTLSQSLL------LDITPEINPLPK 702 E T V + S D+ + ++ LSQ L+ +I PE L Sbjct: 1785 EEHTRVTDESIPSYSGSDMPRNDINMWSKVTEEGTELSQRLVRSGFAGTEIDPENEEL-M 1843 Query: 703 IEVSESVEYEAGHIPSPVIPQESSVEIDNETEQKSESFSSIEKPSITYETNKVNELMDNI 762 + +S ++ + + S +E T+ + S +K T EL + + Sbjct: 1844 LNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERL 1903 Query: 763 IKEDVNSMQIFTKLS--ETIVPPINTATVPDNEDGEAKMNIADTAKQTLISVVDSSSLPE 820 +E Q+ +LS E ++ + K +I D +Q L+ S+ L E Sbjct: 1904 HEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCA--SNRLQE 1961 Query: 821 VK-EEEQSPEDALLRGLQRTATDFYA---ELQNSTDLGYANGNLVHGSNQKESVFMRLNN 876 ++ E++Q E+ L Q+ A A E Q + + Q E V L Sbjct: 1962 LEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQK 2021 Query: 877 RIKALEVNMSLS-GRYLE-------------ELSQRYRKQMEEMQK-------------- 908 ++KALE+++ R++E + +Q KQ+E+M+K Sbjct: 2022 QVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERD 2081 Query: 909 AFNKTIVKLQNTSRIA---EEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSD 965 F + I KL+ ++ + + QT ++ L L T S L + +L+R++ + Sbjct: 2082 VFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQE 2141 Query: 966 R 966 R Sbjct: 2142 R 2142 >gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] Length = 3899 Score = 38.5 bits (88), Expect = 0.039 Identities = 74/361 (20%), Positives = 137/361 (37%), Gaps = 46/361 (12%) Query: 649 EAETVVLGDLSSSMHQDDLVNHTVDAVELEPSHSQTLSQSLL------LDITPEINPLPK 702 E T V + S D+ + ++ LSQ L+ +I PE L Sbjct: 1785 EEHTRVTDESIPSYSGSDMPRNDINMWSKVTEEGTELSQRLVRSGFAGTEIDPENEEL-M 1843 Query: 703 IEVSESVEYEAGHIPSPVIPQESSVEIDNETEQKSESFSSIEKPSITYETNKVNELMDNI 762 + +S ++ + + S +E T+ + S +K T EL + + Sbjct: 1844 LNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERL 1903 Query: 763 IKEDVNSMQIFTKLS--ETIVPPINTATVPDNEDGEAKMNIADTAKQTLISVVDSSSLPE 820 +E Q+ +LS E ++ + K +I D +Q L+ S+ L E Sbjct: 1904 HEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCA--SNRLQE 1961 Query: 821 VK-EEEQSPEDALLRGLQRTATDFYA---ELQNSTDLGYANGNLVHGSNQKESVFMRLNN 876 ++ E++Q E+ L Q+ A A E Q + + Q E V L Sbjct: 1962 LEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQK 2021 Query: 877 RIKALEVNMSLS-GRYLE-------------ELSQRYRKQMEEMQK-------------- 908 ++KALE+++ R++E + +Q KQ+E+M+K Sbjct: 2022 QVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERD 2081 Query: 909 AFNKTIVKLQNTSRIA---EEQDQRQTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSD 965 F + I KL+ ++ + + QT ++ L L T S L + +L+R++ + Sbjct: 2082 VFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQE 2141 Query: 966 R 966 R Sbjct: 2142 R 2142 >gi|222537714 taxilin beta [Homo sapiens] Length = 684 Score = 38.1 bits (87), Expect = 0.051 Identities = 54/295 (18%), Positives = 116/295 (39%), Gaps = 36/295 (12%) Query: 677 LEPSHSQTLSQSLLLDITPEINPLPKIEVSESVEYEAGH-IPSPVIPQESSVEIDNETEQ 735 +E +HS+ LS + + LP +E E G P+PV P E + Sbjct: 1 MEANHSEQLSAERQSTPPGDSSSLPS---HNGLEKEDGQDSPTPVQPPEKEASVH----- 52 Query: 736 KSESFSSIEKPSITYETNKVNELMDNIIKEDVNSMQIFTKLSETIVPPINTATVPDNEDG 795 P I+ E N+ E + N ++ + P A PDNEDG Sbjct: 53 ----------PDISEELNRQLEDIINTYGSAASTAGKEGSARASEQP--ENAESPDNEDG 100 Query: 796 EAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGY 855 + + + ++ + S + V +EQ E +L+GL + A +L Sbjct: 101 DCEETTEEAGREPVASGEPPTVKEPVSNKEQKLEKKILKGLGKEA-----------NLLM 149 Query: 856 ANGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIV 915 N N + +K + + + L++ + +K+ +++Q ++ I+ Sbjct: 150 QNLNKLQTPEEKFDFLFKKYAELLDEHRTEQKKLKLLQKKQVQIQKEKDQLQGEHSRAIL 209 Query: 916 ---KLQNTSRIAEEQDQR-QTEAIQLLQAQLTNMTQLVSNLSATVAELKREVSDR 966 KL++ R + ++ + EA+Q + + ++ S+ +T+ +++ ++ + Sbjct: 210 ARSKLESLCRELQRHNKTLKEEALQRAREEEEKRKEITSHFQSTLTDIQGQIEQQ 264 >gi|20070262 TNF receptor-associated factor 3 interacting protein 1 isoform 1 [Homo sapiens] Length = 691 Score = 38.1 bits (87), Expect = 0.051 Identities = 75/355 (21%), Positives = 134/355 (37%), Gaps = 50/355 (14%) Query: 649 EAETVVLGDLSSSMHQDDLVNHTVDAVELEPSHSQTLSQSLLLDITPEINPLPKIEVSES 708 E ET + S S+ + ++VE +S L I IN P E + S Sbjct: 327 ETETEISTRASKSLTTKTSKRRSKNSVE--GRKEDNISAKSLDSIVSGINNEPNQETTTS 384 Query: 709 -VEYEAGHIPSPVIPQESSVEI------DNETE-QKSESFSSIE---------KPSITYE 751 + + +I S I ++S + N TE QK +S S E K + Sbjct: 385 EIGTKEANINSTSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDAGPAGQDKSEVPET 444 Query: 752 TNKVNELMDNIIK-----------------EDVNSMQIFTKLSETIVPPINTATVPDNED 794 NEL NI + + + ++Q+ S V N T N D Sbjct: 445 PEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVS--NVITESHNSD 502 Query: 795 GEAKMNIADTAKQTLISVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLG 854 E A L + + + V+ EE+ L++ + T D Y +LQ S G Sbjct: 503 NEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKD-YEKLQQSPKPG 561 Query: 855 YANGNLVHGSNQKESVFM-----RLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKA 909 +L + +KE + +L I+ L + G+ ++ + + E+Q Sbjct: 562 EKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCKSALPLGKIMDYIQEDVDAMQNELQMW 621 Query: 910 FNKTIVKLQNTSRIAEEQDQRQTE-AIQLLQAQLTNMTQLVSNLSATVAELKREV 963 ++ + A +Q+QR T+ A++ L+A+L + QL+ + + +K + Sbjct: 622 HSENRQHAE-----ALQQEQRITDCAVEPLKAELAELEQLIKDQQDKICAVKANI 671 >gi|83716024 kinesin family member 21B [Homo sapiens] Length = 1624 Score = 38.1 bits (87), Expect = 0.051 Identities = 47/192 (24%), Positives = 79/192 (41%), Gaps = 35/192 (18%) Query: 811 SVVDSSSLPEVKEEEQSPEDALLRGLQRTATDFYAELQNSTDLGYANGNLVHGSNQKESV 870 S+VDS S PE KE + A L EL+NS L +Q E Sbjct: 617 SLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENS------QRRLQTLKHQYEEK 670 Query: 871 FMRLNNRIKALEV-------NMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQ----- 918 + L N+I+ ++ N+S Y EE + + + E+ + N+ + KLQ Sbjct: 671 LILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKE 730 Query: 919 ------NTSRIAEEQDQRQTEAIQLLQAQLTNMTQL----------VSNLSATVAELKRE 962 N SR E + Q E ++ +A++ M Q+ + + +A+LK+E Sbjct: 731 HARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKE 790 Query: 963 VSDRQSYLVISL 974 RQ + + +L Sbjct: 791 -QRRQEFQIRAL 801 Score = 30.8 bits (68), Expect = 8.2 Identities = 25/88 (28%), Positives = 44/88 (50%), Gaps = 6/88 (6%) Query: 892 LEELSQRYRKQMEEM---QKAFNKTIVKLQNTSRIAEEQDQRQTEAIQLLQAQLTNMTQL 948 LE +R K+ EE+ Q+A + +LQ S E+ Q E I++L A + + Sbjct: 936 LEADMERLIKKREELFLLQEALRRKRERLQAESPEEEKGLQELAEEIEVLAANIDYINDG 995 Query: 949 VSNLSATVAEL---KREVSDRQSYLVIS 973 +++ AT+ +L K E+ + +VIS Sbjct: 996 ITDCQATIVQLEETKEELDSTDTSVVIS 1023 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.126 0.349 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 45,560,795 Number of Sequences: 37866 Number of extensions: 2142515 Number of successful extensions: 9732 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 34 Number of HSP's successfully gapped in prelim test: 265 Number of HSP's that attempted gapping in prelim test: 9083 Number of HSP's gapped (non-prelim): 952 length of query: 1210 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1096 effective length of database: 13,930,794 effective search space: 15268150224 effective search space used: 15268150224 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.