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Search of human proteins with 16905517
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16905517 FUS interacting protein (serine-arginine rich) 1
isoform 2 [Homo sapiens]
(262 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16905517 FUS interacting protein (serine-arginine rich) 1 iso... 533 e-152
gi|5730079 FUS interacting protein (serine-arginine rich) 1 isof... 342 3e-94
gi|169161980 PREDICTED: similar to FUS interacting protein (seri... 335 2e-92
gi|148612890 serine-arginine repressor protein [Homo sapiens] 241 4e-64
gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens] 129 3e-30
gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] 128 6e-30
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 111 6e-25
gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens] 110 1e-24
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 104 7e-23
gi|4506901 splicing factor, arginine/serine-rich 3 [Homo sapiens] 97 2e-20
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi... 92 5e-19
gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens] 89 4e-18
gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens] 89 4e-18
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 86 4e-17
gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens] 85 6e-17
gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ... 81 1e-15
gi|20911035 peptidylprolyl isomerase-like 4 [Homo sapiens] 80 2e-15
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 78 9e-15
gi|9558733 transformer-2 alpha [Homo sapiens] 75 4e-14
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 75 6e-14
gi|4502847 cold inducible RNA binding protein [Homo sapiens] 75 8e-14
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 73 3e-13
gi|52426743 cisplatin resistance-associated overexpressed protei... 72 5e-13
gi|19923485 cisplatin resistance-associated overexpressed protei... 72 5e-13
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 72 6e-13
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 71 8e-13
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 71 8e-13
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 70 2e-12
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 70 2e-12
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 70 2e-12
>gi|16905517 FUS interacting protein (serine-arginine rich) 1
isoform 2 [Homo sapiens]
Length = 262
Score = 533 bits (1372), Expect = e-152
Identities = 262/262 (100%), Positives = 262/262 (100%)
Query: 1 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 60
MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED
Sbjct: 1 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 60
Query: 61 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 120
VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR
Sbjct: 61 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 120
Query: 121 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSR 180
SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSR
Sbjct: 121 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSR 180
Query: 181 SRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSR 240
SRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSR
Sbjct: 181 SRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSR 240
Query: 241 SQSRSRSKSRSRSWTSPKSSGH 262
SQSRSRSKSRSRSWTSPKSSGH
Sbjct: 241 SQSRSRSKSRSRSWTSPKSSGH 262
>gi|5730079 FUS interacting protein (serine-arginine rich) 1 isoform
1 [Homo sapiens]
Length = 183
Score = 342 bits (876), Expect = 3e-94
Identities = 164/164 (100%), Positives = 164/164 (100%)
Query: 1 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 60
MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED
Sbjct: 1 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 60
Query: 61 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 120
VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR
Sbjct: 61 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 120
Query: 121 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDR 164
SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDR
Sbjct: 121 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDR 164
Score = 28.9 bits (63), Expect = 4.8
Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
Query: 206 RGTSKTDSKTHYKSGSRYEKESRKKEPPR-SKSQSRSQSRSRSKSRSRSWTSPKS 259
+G KT ++ K G SR + R +S+SRS R RS+SRS + +S
Sbjct: 87 QGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRS 141
>gi|169161980 PREDICTED: similar to FUS interacting protein
(serine-arginine rich) 1, partial [Homo sapiens]
Length = 181
Score = 335 bits (860), Expect = 2e-92
Identities = 163/164 (99%), Positives = 163/164 (99%), Gaps = 1/164 (0%)
Query: 1 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 60
MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED
Sbjct: 1 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 60
Query: 61 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 120
VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR
Sbjct: 61 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 120
Query: 121 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDR 164
SRSYERRRSRSRSFDYNYRRSYSPRN RPTGRPRRSRSHSDNDR
Sbjct: 121 SRSYERRRSRSRSFDYNYRRSYSPRN-RPTGRPRRSRSHSDNDR 163
Score = 28.9 bits (63), Expect = 4.8
Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
Query: 206 RGTSKTDSKTHYKSGSRYEKESRKKEPPR-SKSQSRSQSRSRSKSRSRSWTSPKS 259
+G KT ++ K G SR + R +S+SRS R RS+SRS + +S
Sbjct: 87 QGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRS 141
>gi|148612890 serine-arginine repressor protein [Homo sapiens]
Length = 261
Score = 241 bits (616), Expect = 4e-64
Identities = 151/276 (54%), Positives = 172/276 (62%), Gaps = 37/276 (13%)
Query: 1 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 60
MSRY RPPNTSLF+RNVAD TR EDLRREFGRYGPIVDVY+PLDFYTRRPRGFAYVQFED
Sbjct: 1 MSRYTRPPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFED 60
Query: 61 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 120
VRDAEDAL+NL+RKW+CGRQIEIQFAQGDRKTP QMK+KE R+ S S +RRSR
Sbjct: 61 VRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKE-RHPCSPS------DHRRSR 113
Query: 121 SRSYERRRSRSRSFDYNYRR------------SYSPRNSRPTGRPRRS----RSHSDNDR 164
S S R RSRS S+ N RR SYS SR PRRS +S +
Sbjct: 114 SPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRRN 173
Query: 165 FKHRNRSFS-----RSKSNSRSRSKSQPKKEMKAKSRSRS-ASHTKTRGTSKTDSKTHYK 218
F R RS S RSKS +S+S S P+K+ + ++SRS H+ + S S Y
Sbjct: 174 FGSRGRSRSKSLQKRSKSIGKSQS-SSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYT 232
Query: 219 SGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSW 254
+ S K S RS SRSRS SW
Sbjct: 233 N-------SETKVQTAKHSHFRSHSRSRSYRHKNSW 261
Score = 37.4 bits (85), Expect = 0.013
Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 2/73 (2%)
Query: 190 EMKAKSRS--RSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRS 247
+MK+K R + H ++R S+ +++ S R + S + R + S SQS+SRS
Sbjct: 95 QMKSKERHPCSPSDHRRSRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRS 154
Query: 248 KSRSRSWTSPKSS 260
KS R TS + S
Sbjct: 155 KSLPRRSTSARQS 167
>gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]
Length = 221
Score = 129 bits (323), Expect = 3e-30
Identities = 99/253 (39%), Positives = 132/253 (52%), Gaps = 48/253 (18%)
Query: 4 YLRPPN-----TSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQF 58
Y RPP TSL V N+ T + LRR F +YG + DVY+P D YT+ RGFA+V+F
Sbjct: 3 YGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRF 62
Query: 59 EDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRR 118
D RDAEDA+ +D + GR++ +Q A+ R P+ ++ G RY RR
Sbjct: 63 HDKRDAEDAMDAMDGAVLDGRELRVQMARYGR-PPDSHHSRRGP---PPRRYGGGGYGRR 118
Query: 119 SRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSN 178
SRS RRRSRSRS RS S RSRS S R K R+R+ SRS+S
Sbjct: 119 SRS-PRRRRRSRSRS------RSRS-----------RSRSRSRYSRSKSRSRTRSRSRST 160
Query: 179 SRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQ 238
S+SRS + K + + SRSRS S +++R S PP SK +
Sbjct: 161 SKSRSARRSKSKSSSVSRSRSRSRSRSRSRS---------------------PPPVSKRE 199
Query: 239 SRSQSRSRSKSRS 251
S+S+SRS+S +S
Sbjct: 200 SKSRSRSKSPPKS 212
>gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]
Length = 282
Score = 128 bits (321), Expect = 6e-30
Identities = 93/260 (35%), Positives = 132/260 (50%), Gaps = 12/260 (4%)
Query: 11 SLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHN 70
+L V N+ T + LRR F +YG + DVY+P + +T+ PRGFA+V+F D RDA+DA
Sbjct: 15 TLKVDNLTYRTSPDSLRRVFEKYGRVGDVYIPREPHTKAPRGFAFVRFHDRRDAQDAEAA 74
Query: 71 LDRKWICGRQIEIQFAQ-GDRKTPNQMKAKE---------GRNVYSSSRYDDYDRYR-RS 119
+D + GR++ +Q A+ G R P + + GR S R R R RS
Sbjct: 75 MDGAELDGRELRVQVARYGRRDLPRSRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHRS 134
Query: 120 RSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNS 179
RSR RSRSRS R S SP + P R R SRS R++ S S+
Sbjct: 135 RSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSSG 194
Query: 180 RSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQS 239
S S+ ++ S+S S++ +++ TSK+ S KS S SR + ++S
Sbjct: 195 YSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSPP 254
Query: 240 RSQSRSRSKSRSRSWTSPKS 259
R S+ +SKSRSRS PKS
Sbjct: 255 R-VSKRKSKSRSRSKRPPKS 273
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 111 bits (278), Expect = 6e-25
Identities = 81/273 (29%), Positives = 137/273 (50%), Gaps = 40/273 (14%)
Query: 12 LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
+++ ++ R D+ R F YG I++V + G+ +V+F+D+RDA+DA++ L
Sbjct: 4 VYIGRLSYQARERDVERFFKGYGKILEVDLK--------NGYGFVEFDDLRDADDAVYEL 55
Query: 72 DRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRS 131
+ K +CG ++ ++ A+G R+ + + G Y S D Y R+ R S
Sbjct: 56 NGKDLCGERVIVEHARGPRRDGSYGSGRSGYG-YRRSGRDKYGPPTRTEYRLIVENLSSR 114
Query: 132 RSFD--YNYRRSYSPRNSRPTGRPRRSR------SHSDNDRF------------------ 165
S+ +Y R + R++ S+SD R
Sbjct: 115 CSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVE 174
Query: 166 ----KHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGS 221
R RS+SRS+S+SRSRS+S+ ++ +++S S +SH+K+R S++ S++ KS S
Sbjct: 175 DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS 234
Query: 222 RYEKESR-KKEPPRSKSQSRSQSRSRSKSRSRS 253
R + SR KKE RS S+ +S+SRS S +SRS
Sbjct: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRS 267
Score = 98.2 bits (243), Expect = 6e-21
Identities = 90/290 (31%), Positives = 137/290 (47%), Gaps = 39/290 (13%)
Query: 3 RYLRPPNTS--LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 60
+Y P T L V N++ +DL+ + G + D + R + ++F
Sbjct: 95 KYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYA----DAHKGR-KNEGVIEFVS 149
Query: 61 VRDAEDALHNLDRKWICGRQIE-IQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYR-- 117
D + AL LD + GR+I ++ G R+ + +++ S SR+ R R
Sbjct: 150 YSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSG 209
Query: 118 ---------RSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHS-------- 160
RSRSRS R RS+SRS + RS ++ P+ RSRSHS
Sbjct: 210 SSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKS 269
Query: 161 ---------DNDRF-KHRNRSFSRSKSNSRSRSKSQPKK--EMKAKSRSRSASHTKTRGT 208
+ND K ++RS SR KS S+SRS+SQ ++ E K S SR S K+
Sbjct: 270 KDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQ 329
Query: 209 SKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPK 258
S++ S++ S SR S+ K+ + + +SR +SRSRS+SRS+S S K
Sbjct: 330 SRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRK 379
Score = 79.7 bits (195), Expect = 2e-15
Identities = 55/171 (32%), Positives = 90/171 (52%), Gaps = 5/171 (2%)
Query: 90 RKTPNQMKAKEGRNVYSSSRYDDYDRYR-RSRSRSYERRRSRSRSFDYNYRRSYSPRNSR 148
R++ ++ ++K G S SR D+ + R RSR R RSRSRS R+ S R+S+
Sbjct: 328 RQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSK 387
Query: 149 PTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGT 208
++ + +D + ++RS SRS S R +KS+ + + ++ +TR
Sbjct: 388 AGSSKKKKKEDTD----RSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSR 443
Query: 209 SKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKS 259
S+++SK+ S S+ RS+S+SRS+S SRS SRSRS + +S
Sbjct: 444 SRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 76.3 bits (186), Expect = 3e-14
Identities = 49/136 (36%), Positives = 71/136 (52%), Gaps = 4/136 (2%)
Query: 118 RSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKS 177
+SRS S + +S+SRS R R S GR + R + + S SRS+S
Sbjct: 287 KSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRS 346
Query: 178 NSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKS 237
S+S+ K + +K + +SRSRS S +K+ + K SK K+GS +KK+ +S
Sbjct: 347 RSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGS----SKKKKKEDTDRS 402
Query: 238 QSRSQSRSRSKSRSRS 253
QSRS SRS SK R +
Sbjct: 403 QSRSPSRSVSKEREHA 418
Score = 72.4 bits (176), Expect = 4e-13
Identities = 66/182 (36%), Positives = 90/182 (49%), Gaps = 40/182 (21%)
Query: 118 RSRSRSYERRR--------SRSRSFDYNYRRSYSPRNSRPTGRPR-RSRSHSDNDRFKHR 168
+SRSRS ERR SR RS + + R+S S S+ R R RSRS S D+ K R
Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS-KDKRKGR 357
Query: 169 NRSFSRSKSNSRSRSKSQ------------------PKKEMKAKSRSRSAS--------H 202
RS S+S SRSRSKS+ KKE +S+SRS S H
Sbjct: 358 KRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREH 417
Query: 203 TKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSK----SQSRSQSRSRSKSRSRSWTSPK 258
K+ + + +G+ E SR + +SK S+SRS+S+S SK+RSRS + +
Sbjct: 418 AKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSR 477
Query: 259 SS 260
S+
Sbjct: 478 SA 479
>gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens]
Length = 238
Score = 110 bits (276), Expect = 1e-24
Identities = 99/273 (36%), Positives = 133/273 (48%), Gaps = 55/273 (20%)
Query: 1 MSRYLR-PPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFE 59
MSRY R T ++V N+ +L R F YGP+ V++ R P GFA+V+FE
Sbjct: 1 MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWI-----ARNPPGFAFVEFE 55
Query: 60 DVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDD------- 112
D RDAEDA+ LD K ICG ++ ++ + G + + R + R +
Sbjct: 56 DPRDAEDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHY 115
Query: 113 -YDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRS 171
YD +R SR RRRSRSRS RSHS + R R
Sbjct: 116 AYDCHRYSR-----RRRSRSRS-----------------------RSHS-----RSRGRR 142
Query: 172 FSRSKSNSR---SRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESR 228
+SRS+S SR SRS S + + RSRSAS ++R S S+ +++S SR SR
Sbjct: 143 YSRSRSRSRGRRSRSASPRRSRSISLRRSRSASLRRSRSGSIKGSR-YFQSPSRSRSRSR 201
Query: 229 KKEPPRSKSQSRSQSRSRSKSRSRSWT-SPKSS 260
PRS SRS+SRS S RSRS + SP+ S
Sbjct: 202 SISRPRS---SRSKSRSPSPKRSRSPSGSPRRS 231
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 104 bits (260), Expect = 7e-23
Identities = 85/292 (29%), Positives = 141/292 (48%), Gaps = 52/292 (17%)
Query: 12 LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
+++ ++ + R +D++R F YG +++V + G+ +V+FED RDA+DA++ L
Sbjct: 4 VYIGRLSYNVREKDIQRFFSGYGRLLEVDLK--------NGYGFVEFEDSRDADDAVYEL 55
Query: 72 DRKWICGRQIEIQFAQGDRKTPN--QMKAKEGRNVYSSSRYDDYDRY------------- 116
+ K +CG ++ ++ A+G R+ + ++ G YSS R D+Y
Sbjct: 56 NGKELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVE 115
Query: 117 ---------------RRSRSRSYERRRSRSRSFDYNYRRSYSPRN---SRPTG---RPRR 155
R++ +Y + RSYS + G R
Sbjct: 116 NLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRN 175
Query: 156 SRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKT 215
R D R HR RS+S S+S SRSR +S+ + ++SRSRS S +++R S++ ++
Sbjct: 176 IRLIEDKPRTSHR-RSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRS 234
Query: 216 HYKSGSRYEKESRKKEPPRSKSQSRSQSRSRS-----KSRSRSWT-SPKSSG 261
+S R + S+ K P+S S S SRSRS KSRSRS + SPK +G
Sbjct: 235 RSRSKGR-KSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENG 285
Score = 86.3 bits (212), Expect = 3e-17
Identities = 82/214 (38%), Positives = 108/214 (50%), Gaps = 32/214 (14%)
Query: 56 VQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDR 115
++F D + AL LD I GR I + + +T + R YS SR R
Sbjct: 151 IEFRSYSDMKRALDKLDGTEINGRNIRL--IEDKPRTSH-------RRSYSGSRSRSRSR 201
Query: 116 YRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRS 175
RRSRSRS RSRSRS + RS SR GR R SRS R K +++ S
Sbjct: 202 -RRSRSRSRRSSRSRSRSISKSRSRS----RSRSKGRSR-SRSKGRKSRSKSKSKPKSDR 255
Query: 176 KSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEP--- 232
S+S SRS+S+ + E K++SRSRS S K + K KS SR +SR P
Sbjct: 256 GSHSHSRSRSKDEYE-KSRSRSRSRS-------PKENGKGDIKSKSRSRSQSRSNSPLPV 307
Query: 233 PRSKSQS------RSQSRSRSKSRSRSWTSPKSS 260
P SK++S R+ SRSRS+SRS+S + +SS
Sbjct: 308 PPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSS 341
>gi|4506901 splicing factor, arginine/serine-rich 3 [Homo sapiens]
Length = 164
Score = 96.7 bits (239), Expect = 2e-20
Identities = 63/184 (34%), Positives = 93/184 (50%), Gaps = 21/184 (11%)
Query: 1 MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFED 60
M R P + ++V N+ ++ +L R FG YGP+ V+V R P GFA+V+FED
Sbjct: 1 MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWV-----ARNPPGFAFVEFED 55
Query: 61 VRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSR 120
RDA DA+ LD + +CG ++ ++ + G++++ N+ + DDY R R
Sbjct: 56 PRDAADAVRELDGRTLCGCRVRVELSNGEKRSRNRGPPPS----WGRRPRDDY----RRR 107
Query: 121 SRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSR 180
S RR R RRS+S SR R RR +R +RSFSRS+S SR
Sbjct: 108 SPPPRRRSPR--------RRSFSRSRSRSLSRDRRRERSLSRERNHKPSRSFSRSRSRSR 159
Query: 181 SRSK 184
S +
Sbjct: 160 SNER 163
Score = 28.9 bits (63), Expect = 4.8
Identities = 17/49 (34%), Positives = 25/49 (51%), Gaps = 6/49 (12%)
Query: 220 GSRYEKESRKKEPP------RSKSQSRSQSRSRSKSRSRSWTSPKSSGH 262
G R + R++ PP R +S SRS+SRS S+ R R + + H
Sbjct: 97 GRRPRDDYRRRSPPPRRRSPRRRSFSRSRSRSLSRDRRRERSLSRERNH 145
>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
sapiens]
Length = 437
Score = 92.0 bits (227), Expect = 5e-19
Identities = 81/276 (29%), Positives = 115/276 (41%), Gaps = 39/276 (14%)
Query: 11 SLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHN 70
+LFV V DT LRREF YGPI +++ + +PRG+A++++E RD A +
Sbjct: 104 TLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKH 163
Query: 71 LDRKWICGRQIEIQFAQGDRK---TPNQMKAKEGR--------NVYSSSRYDDYDRY--- 116
D K I GR++ + +G P ++ G N+ S R DD RY
Sbjct: 164 ADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGR-DDTSRYDER 222
Query: 117 -------RRSRSRSYER-RRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHR 168
R R R ER RR RSR D R R SR R RRSRS +R + R
Sbjct: 223 PGPSPLPHRDRDRDRERERRERSRERDKERER----RRSRSRDRRRRSRSRDKEERRRSR 278
Query: 169 NRSFSRSKSNSR--SRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSK----------TH 216
RS + + R SRS+ + ++E + K R + D+
Sbjct: 279 ERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPD 338
Query: 217 YKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSR 252
G + R +E RS R + R R + R R
Sbjct: 339 GPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDR 374
Score = 36.2 bits (82), Expect = 0.030
Identities = 39/160 (24%), Positives = 52/160 (32%), Gaps = 42/160 (26%)
Query: 89 DRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYE-RRRSRSRSFDYNYRRSYSPRNS 147
DR+ + +++E R DR RRSRSR E RRRSR RS D + R S
Sbjct: 236 DRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRS 295
Query: 148 RPTGRPRRSRSHS----------------------------------------DNDRFKH 167
R R R R D DR +
Sbjct: 296 RERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERR 355
Query: 168 RNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRG 207
R+ R + R R + + +E K R + RG
Sbjct: 356 RSHRSERERRRDRDRDRDR-DREHKRGERGSERGRDEARG 394
>gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens]
Length = 272
Score = 89.0 bits (219), Expect = 4e-18
Identities = 78/282 (27%), Positives = 129/282 (45%), Gaps = 64/282 (22%)
Query: 12 LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
+F+ + R +D+ R F YG I D+ + RGF +V+FED RDA+DA++ L
Sbjct: 6 VFIGRLNPAAREKDVERFFKGYGRIRDIDLK--------RGFGFVEFEDPRDADDAVYEL 57
Query: 72 DRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYS---SSRYDDYDRYRRSRSRSYER-- 126
D K +C ++ I+ A+ + + GR YS SSR DR R+ R
Sbjct: 58 DGKELCSERVTIEHARA------RSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLI 111
Query: 127 -------------RRSRSRSFDYNYRRSYSPR--------------------------NS 147
+ ++ + + ++ P+ N
Sbjct: 112 VENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEING 171
Query: 148 RPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRG 207
R S+ HS + R+RS SR++S+SRSRS+S+ + K+ SRSRS S +++R
Sbjct: 172 RKIKLIEGSKRHS-----RSRSRSRSRTRSSSRSRSRSR-SRSRKSYSRSRSRSRSRSRS 225
Query: 208 TSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKS 249
S++ S++ S+ S + + P S + RS+SRSRS+S
Sbjct: 226 KSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRS 267
>gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens]
Length = 272
Score = 89.0 bits (219), Expect = 4e-18
Identities = 78/282 (27%), Positives = 129/282 (45%), Gaps = 64/282 (22%)
Query: 12 LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
+F+ + R +D+ R F YG I D+ + RGF +V+FED RDA+DA++ L
Sbjct: 6 VFIGRLNPAAREKDVERFFKGYGRIRDIDLK--------RGFGFVEFEDPRDADDAVYEL 57
Query: 72 DRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYS---SSRYDDYDRYRRSRSRSYER-- 126
D K +C ++ I+ A+ + + GR YS SSR DR R+ R
Sbjct: 58 DGKELCSERVTIEHARA------RSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLI 111
Query: 127 -------------RRSRSRSFDYNYRRSYSPR--------------------------NS 147
+ ++ + + ++ P+ N
Sbjct: 112 VENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEING 171
Query: 148 RPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRG 207
R S+ HS + R+RS SR++S+SRSRS+S+ + K+ SRSRS S +++R
Sbjct: 172 RKIKLIEGSKRHS-----RSRSRSRSRTRSSSRSRSRSR-SRSRKSYSRSRSRSRSRSRS 225
Query: 208 TSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKS 249
S++ S++ S+ S + + P S + RS+SRSRS+S
Sbjct: 226 KSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRS 267
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 85.5 bits (210), Expect = 4e-17
Identities = 66/194 (34%), Positives = 99/194 (51%), Gaps = 30/194 (15%)
Query: 89 DRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRS--------RSRSFDYNYRR 140
++ +P++ K KE V S R + Y RSRSRS ER+R RSRS RR
Sbjct: 14 EKTSPDRDKKKEQSEVSVSPRASKH-HYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRR 72
Query: 141 SYS---------------PRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKS 185
S +S GR R + S + DR K + R SR +S+SRSRS+
Sbjct: 73 HESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR- 131
Query: 186 QPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRS 245
++ +++SR R S +++R K+ S++ + SR RK+ R +S+SRS+SR
Sbjct: 132 --ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR---RIRSRSRSRSRH 186
Query: 246 RSKSRSRSWTSPKS 259
R ++RSRS T +S
Sbjct: 187 RHRTRSRSRTRSRS 200
Score = 66.2 bits (160), Expect = 3e-11
Identities = 57/160 (35%), Positives = 83/160 (51%), Gaps = 16/160 (10%)
Query: 89 DRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRN-- 146
DR + K+ GR+ +S SR R RR RSRS ER++SRSRS + RS S
Sbjct: 110 DRHKRKERKSSRGRS-HSRSR----SRERRHRSRSRERKKSRSRSRERKKSRSRSRERKK 164
Query: 147 --SRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSK----SQPKKEMKAKSRSRSA 200
SR R RR RS S R +HR+R+ SRS++ SRSR + +P++ ++ SR+ S
Sbjct: 165 SRSRSRERKRRIRSRS-RSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSP 223
Query: 201 SHTKTRGTSKTDSKTHYKSGSRYEK--ESRKKEPPRSKSQ 238
+ R T+ + + R +K E R+KE + Q
Sbjct: 224 PPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ 263
Score = 62.8 bits (151), Expect = 3e-10
Identities = 52/167 (31%), Positives = 80/167 (47%), Gaps = 20/167 (11%)
Query: 87 QGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRN 146
+ + + + +GR +SS + R+ R S R SRSRS + +R R
Sbjct: 84 KSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRER- 142
Query: 147 SRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTR 206
++SRS S +R K R+RS R KS SRSR + K+ ++++SRSRS +TR
Sbjct: 143 -------KKSRSRS-RERKKSRSRSRERKKSRSRSRER---KRRIRSRSRSRSRHRHRTR 191
Query: 207 GTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRS 253
S+T SR ++ E PR S+S S++ S R R+
Sbjct: 192 SRSRT--------RSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRN 230
Score = 37.0 bits (84), Expect = 0.017
Identities = 33/134 (24%), Positives = 56/134 (41%), Gaps = 5/134 (3%)
Query: 94 NQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRP 153
++ +++E + S SR RSRSRS R R+RSRS + R R +P
Sbjct: 155 SRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFS 214
Query: 154 RRSRSHSDNDRFKHRNRSFSRSKSNSR-----SRSKSQPKKEMKAKSRSRSASHTKTRGT 208
R F+ RN + ++ +R + + Q +KEM K + + + G
Sbjct: 215 RSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGG 274
Query: 209 SKTDSKTHYKSGSR 222
S + SG++
Sbjct: 275 SVLNVAALLASGTQ 288
>gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]
Length = 288
Score = 85.1 bits (209), Expect = 6e-17
Identities = 68/182 (37%), Positives = 88/182 (48%), Gaps = 19/182 (10%)
Query: 8 PNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDA 67
PN L V ++ T DLR F +YGPI DV + D +RR RGFA+V FE+V DA++A
Sbjct: 116 PNCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEA 175
Query: 68 LHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERR 127
+ + GR+I + F+ R GR Y SSR DY Y R R Y+ R
Sbjct: 176 KERANGMELDGRRIRVDFSITKRPHTPTPGIYMGRPTYGSSRRRDY--YDRGYDRGYDDR 233
Query: 128 RSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRS----FSRSKSNSRSRS 183
DY Y RSY G R+ D D+ +R RS +SR SRSRS
Sbjct: 234 -------DY-YSRSYRGGGGGGGG----WRAAQDRDQI-YRRRSPSPYYSRGGYRSRSRS 280
Query: 184 KS 185
+S
Sbjct: 281 RS 282
Score = 51.6 bits (122), Expect = 7e-07
Identities = 38/99 (38%), Positives = 50/99 (50%), Gaps = 13/99 (13%)
Query: 170 RSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSK-THYKSGSRYEKESR 228
+++ +S S SRS S A +SA HT R SK DS+ + KS SR E SR
Sbjct: 7 QNYGERESRSASRSGS-------AHGSGKSARHTPARSRSKEDSRRSRSKSRSRSESRSR 59
Query: 229 KKEPPR-----SKSQSRSQSRSRSKSRSRSWTSPKSSGH 262
+ R S+S+SRS RSRS+S SR + S H
Sbjct: 60 SRRSSRRHYTRSRSRSRSHRRSRSRSYSRDYRRRHSHSH 98
Score = 48.5 bits (114), Expect = 6e-06
Identities = 41/117 (35%), Positives = 57/117 (48%), Gaps = 19/117 (16%)
Query: 119 SRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGR--PRRSRSHSDNDRFKHRNRSFSRSK 176
S ++Y R SRS S RS S S + R P RSRS D+ R SRSK
Sbjct: 4 SGEQNYGERESRSAS------RSGSAHGSGKSARHTPARSRSKEDSRR--------SRSK 49
Query: 177 SNSRSRSKSQPKKEMK---AKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKK 230
S SRS S+S+ ++ + +SRSRS SH ++R S + S S +R++
Sbjct: 50 SRSRSESRSRSRRSSRRHYTRSRSRSRSHRRSRSRSYSRDYRRRHSHSHSPMSTRRR 106
Score = 44.7 bits (104), Expect = 8e-05
Identities = 35/93 (37%), Positives = 47/93 (50%), Gaps = 18/93 (19%)
Query: 115 RYRRSRSRSYE-RRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFS 173
R+ +RSRS E RRSRS+S + RS S R+SR +H RS S
Sbjct: 31 RHTPARSRSKEDSRRSRSKSRSRSESRSRSRRSSR-----------------RHYTRSRS 73
Query: 174 RSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTR 206
RS+S+ RSRS+S + + S S S T+ R
Sbjct: 74 RSRSHRRSRSRSYSRDYRRRHSHSHSPMSTRRR 106
Score = 44.3 bits (103), Expect = 1e-04
Identities = 26/70 (37%), Positives = 38/70 (54%)
Query: 94 NQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRP 153
++ K++ S SR Y RSRSRS RRSRSRS+ +YRR +S +S + R
Sbjct: 46 SRSKSRSRSESRSRSRRSSRRHYTRSRSRSRSHRRSRSRSYSRDYRRRHSHSHSPMSTRR 105
Query: 154 RRSRSHSDND 163
R + ++ D
Sbjct: 106 RHVGNRANPD 115
Score = 41.6 bits (96), Expect = 7e-04
Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
Query: 114 DRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFS 173
+R RS SRS S +S + RS S +SR + RSRS S + + R ++
Sbjct: 11 ERESRSASRSGSAHGS-GKSARHTPARSRSKEDSRRSRSKSRSRSESRSRSRRSSRRHYT 69
Query: 174 RSKSNSRSRSKSQPKKEMKAKSRSRSASHT 203
RS+S SRS +S+ + + R S SH+
Sbjct: 70 RSRSRSRSHRRSRSRSYSRDYRRRHSHSHS 99
Score = 37.0 bits (84), Expect = 0.017
Identities = 31/78 (39%), Positives = 43/78 (55%), Gaps = 14/78 (17%)
Query: 181 SRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSR 240
S S Q E +++S SRS S G+ K S H + SR +++SR+ SR
Sbjct: 2 SDSGEQNYGERESRSASRSGS---AHGSGK--SARHTPARSRSKEDSRR---------SR 47
Query: 241 SQSRSRSKSRSRSWTSPK 258
S+SRSRS+SRSRS S +
Sbjct: 48 SKSRSRSESRSRSRRSSR 65
Score = 36.6 bits (83), Expect = 0.023
Identities = 31/74 (41%), Positives = 37/74 (50%), Gaps = 8/74 (10%)
Query: 90 RKTPNQMKAKEGRN---VYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRN 146
R TP + ++KE S SR + R RRS R Y R RSRS ++RRS S
Sbjct: 31 RHTPARSRSKEDSRRSRSKSRSRSESRSRSRRSSRRHYTRSRSRS----RSHRRSRSRSY 86
Query: 147 SRPTGRPRRSRSHS 160
SR R R S SHS
Sbjct: 87 SRDY-RRRHSHSHS 99
>gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
sapiens]
Length = 482
Score = 80.9 bits (198), Expect = 1e-15
Identities = 72/267 (26%), Positives = 111/267 (41%), Gaps = 57/267 (21%)
Query: 24 EDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNLDRKWICGRQIEI 83
ED+ EF G ++ V + RG YVQ++ + + AL + +W GRQ++
Sbjct: 241 EDVLPEFKNVGKVIQFKVSCNLEPHL-RGNVYVQYQSEEECQAALSLFNGRWYAGRQLQC 299
Query: 84 QFAQGDR--------------------------KTPNQMKAKEGRNVYSSSRYDDYDRYR 117
+F R + PN + R++Y S DR
Sbjct: 300 EFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYLSP-----DRTG 354
Query: 118 RSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKS 177
S ++ ERR DY Y R RN P + S+ R+
Sbjct: 355 SSFGKNSERRERMGHHDDY-YSRLRGRRNPSP-------------------DHSYKRNGE 394
Query: 178 NSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKS-GSRYEKESRKKEPPRSK 236
+ R S+ + KK K S+SR ++++RG ++ S+ + GSR SR + RS+
Sbjct: 395 SERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSR 454
Query: 237 SQSRSQSRSRSKSRS----RSWTSPKS 259
SQS S+SRSR + RS R+ SPKS
Sbjct: 455 SQSSSRSRSRGRRRSGNRDRTVQSPKS 481
>gi|20911035 peptidylprolyl isomerase-like 4 [Homo sapiens]
Length = 492
Score = 79.7 bits (195), Expect = 2e-15
Identities = 60/262 (22%), Positives = 110/262 (41%), Gaps = 20/262 (7%)
Query: 5 LRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDA 64
++PP LFV + T EDL F R+GPI V D+ T +A+++FE D
Sbjct: 235 IKPPENVLFVCKLNPVTTDEDLEIIFSRFGPIRSCEVIRDWKTGESLCYAFIEFEKEEDC 294
Query: 65 EDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDY----------- 113
E A +D I R+I + F+Q K + K K G+ Y+ S + +Y
Sbjct: 295 EKAFFKMDNVLIDDRRIHVDFSQSVAKV--KWKGKGGK--YTKSDFKEYEKEQDKPPNLV 350
Query: 114 --DRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRS 171
D+ + + Y+ + S ++ + T + D K+ N+
Sbjct: 351 LKDKVKPKQDTKYDLILDEQAEDSKSSHSHTSKKHKKKTHHCSEEKEDEDYMPIKNTNQD 410
Query: 172 FSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKE 231
R + ++ K++ R R+ + +++R + HY + + + ++ E
Sbjct: 411 IYREMGFGHYEEEESCWEKQKSEKRDRTQNRSRSRSRERDG---HYSNSHKSKYQTDLYE 467
Query: 232 PPRSKSQSRSQSRSRSKSRSRS 253
RSK + RS+S +SK + +S
Sbjct: 468 RERSKKRDRSRSPKKSKDKEKS 489
Score = 35.4 bits (80), Expect = 0.051
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 3/109 (2%)
Query: 90 RKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRP 149
+KT + + KE + Y + + D YR YE S + +R + SR
Sbjct: 387 KKTHHCSEEKEDED-YMPIKNTNQDIYREMGFGHYEEEESCWEK-QKSEKRDRTQNRSRS 444
Query: 150 TGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSR 198
R R +S++ + K++ + R +S R RS+S K + K KS+ R
Sbjct: 445 RSRERDGH-YSNSHKSKYQTDLYERERSKKRDRSRSPKKSKDKEKSKYR 492
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 77.8 bits (190), Expect = 9e-15
Identities = 49/146 (33%), Positives = 82/146 (56%), Gaps = 8/146 (5%)
Query: 117 RRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSK 176
RR RS ++ R S+ RS ++ R S R+ R + PR+ S + ++ R SRS+
Sbjct: 348 RRGRSHNWSRNPSKERSHSHS-RSSSKERDHRGSSSPRKESGRSQSGS-PNKQRDHSRSR 405
Query: 177 SNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSK 236
S +++R +S+ + KA+ RSRS S K R S+ S++ YK+ R SR + P +++
Sbjct: 406 SPNKARDRSRSRSPYKARDRSRSRSPNKARDCSR--SRSPYKARDR----SRSRSPNKAR 459
Query: 237 SQSRSQSRSRSKSRSRSWTSPKSSGH 262
SRS+S ++++ RSRS + K H
Sbjct: 460 DHSRSRSPNKARDRSRSRSPSKERDH 485
Score = 75.9 bits (185), Expect = 3e-14
Identities = 59/188 (31%), Positives = 103/188 (54%), Gaps = 22/188 (11%)
Query: 91 KTPNQMKAKEGRNVYSSSRYDDYDR---------YRRSRSRSYER--RRSRSRSFDYNYR 139
++PN KA++ S S+ D+ + +RRSRS S ER R+SRS S + ++R
Sbjct: 465 RSPN--KARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHR 522
Query: 140 RSYSP------RNSRPTGRPR-RSRSHSDNDRFKHR-NRSFSRSKSNSRSRSKSQPKKEM 191
RS SP R SR + R RS+S S ++ +HR +RS S+ + R RS S+ ++
Sbjct: 523 RSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERR 582
Query: 192 KAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRS 251
+++S S H+++R +K + ++ S+ + SR + P + + S+S++ S+ S
Sbjct: 583 QSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPS 642
Query: 252 RSWTSPKS 259
+S T P+S
Sbjct: 643 QS-TVPRS 649
Score = 75.1 bits (183), Expect = 6e-14
Identities = 57/186 (30%), Positives = 93/186 (50%), Gaps = 21/186 (11%)
Query: 97 KAKEGRNVYSSSRYDDYDRYR-------RSRSRSYERRRSRSR----SFDYNYRRSYSP- 144
KA++ S ++ D+ R R RSRSRS + R S+ S + ++RRS SP
Sbjct: 445 KARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPS 504
Query: 145 -----RNSRPTGRP---RRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSR 196
R SR + + RRSRS S +R + ++RS ++ + S+SRS S+ ++ +++S
Sbjct: 505 KERQCRQSRSSSKERDHRRSRSPS-KERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSP 563
Query: 197 SRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTS 256
S+ + R SK + +S S SR + P + SR ++ S+ K+ SRS T
Sbjct: 564 SKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTP 623
Query: 257 PKSSGH 262
K H
Sbjct: 624 SKEGNH 629
Score = 74.3 bits (181), Expect = 1e-13
Identities = 60/174 (34%), Positives = 86/174 (49%), Gaps = 12/174 (6%)
Query: 89 DRKTPNQMKAKEGRNVYSS-SRYDDYDRYR-------RSRSRSYERRRSRSRSFDYNYRR 140
D + + + + GR+ S ++ D+ R R RSRSRS + R RSRS N R
Sbjct: 376 DHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKAR 435
Query: 141 SYSPRNSRPTGRPRRSRSHSDNDRFKH-RNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRS 199
S R+ P RSRS S N H R+RS ++++ SRSRS S+ + + S S+
Sbjct: 436 DCS-RSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKE 494
Query: 200 ASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRS 253
H ++R SK +S S+ R + P SK + R QSRS +K R RS
Sbjct: 495 RDHRRSRSPSKERQCRQSRSSSKERDHRRSRSP--SKERQRRQSRSPNKERDRS 546
Score = 71.2 bits (173), Expect = 8e-13
Identities = 65/187 (34%), Positives = 91/187 (48%), Gaps = 24/187 (12%)
Query: 90 RKTPNQMKAKEGRNVYSSSRYDDYDRYR---------RSRSRSYERRRSRSR--SFDYNY 138
R++ + K ++ R SSS+ D+ R R +SRS + ER RS+SR S + +
Sbjct: 498 RRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREH 557
Query: 139 RRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSR 198
R+S SP R RR RS S K R R SRS S R S+S+ + SR R
Sbjct: 558 RQSRSPSKERDR---RRWRSPS-----KERERRQSRSSSEERDHSRSRSPNKQSGYSRPR 609
Query: 199 SASHTKTRGTSKTDSKTHYKSGSR---YEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWT 255
++S K S+T SK S SR E + + PRS RS +R+ S S++R T
Sbjct: 610 ASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNR--T 667
Query: 256 SPKSSGH 262
K+S H
Sbjct: 668 PSKTSSH 674
Score = 70.9 bits (172), Expect = 1e-12
Identities = 51/179 (28%), Positives = 95/179 (53%), Gaps = 9/179 (5%)
Query: 91 KTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPT 150
++P + ++ + +S R + R SR+RS R+ S+ ++ RS+S S+
Sbjct: 285 RSPRRSRSGSQKRTHSRVRSHSWKR-NHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQ 343
Query: 151 GR-PRRSRSHSDNDRFKHRNRSFSRSKSNSRS---RSKSQPKKE---MKAKSRSRSASHT 203
R PRR RSH+ + R + RS S S+S+S+ R S P+KE ++ S ++ H+
Sbjct: 344 SRTPRRGRSHNWS-RNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHS 402
Query: 204 KTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSSGH 262
++R +K ++ +S + SR + P +++ SRS+S +++ RSRS + K+ H
Sbjct: 403 RSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDH 461
Score = 70.5 bits (171), Expect = 1e-12
Identities = 54/175 (30%), Positives = 88/175 (50%), Gaps = 19/175 (10%)
Query: 91 KTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPT 150
K+ NQ + +S SR RRSRS S +R SR RS ++++R++S SR
Sbjct: 267 KSYNQASTRSRPQSHSQSRSP-----RRSRSGSQKRTHSRVRS--HSWKRNHSRARSRTR 319
Query: 151 -------GRPRRSRSHS-----DNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSR 198
GR +SRSHS + R R RS + S++ S+ RS S + K +
Sbjct: 320 KGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRG 379
Query: 199 SASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRS 253
S+S K G S++ S + SR ++ ++ RS+S +++ RSRS+S +++
Sbjct: 380 SSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKA 434
Score = 69.7 bits (169), Expect = 2e-12
Identities = 56/172 (32%), Positives = 80/172 (46%), Gaps = 17/172 (9%)
Query: 106 SSSRYDDYDRYR---------RSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRP-RR 155
S S Y DR R SRSRS + R RSRS + R +S S R RR
Sbjct: 440 SRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRR 499
Query: 156 SRSHS-------DNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGT 208
SRS S K R+ SRS S R R +S+ + + +S+SRS S +
Sbjct: 500 SRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQ 559
Query: 209 SKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSS 260
S++ SK + R + R++ RS S+ R SRSRS ++ ++ P++S
Sbjct: 560 SRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRAS 611
Score = 68.6 bits (166), Expect = 5e-12
Identities = 53/146 (36%), Positives = 81/146 (55%), Gaps = 14/146 (9%)
Query: 119 SRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPR---RSRSHS---DNDRFKHRNRS- 171
SR +SY + +RSR ++ +S SPR SR + R R RSHS ++ R + R R
Sbjct: 264 SRVKSYNQASTRSRP--QSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKG 321
Query: 172 -FSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKK 230
S+ +S+SRS S+ K + ++++ R SH +R SK S +H +S S+ E++ R
Sbjct: 322 ILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSK-ERDHRGS 380
Query: 231 EPPR---SKSQSRSQSRSRSKSRSRS 253
PR +SQS S ++ R SRSRS
Sbjct: 381 SSPRKESGRSQSGSPNKQRDHSRSRS 406
Score = 62.8 bits (151), Expect = 3e-10
Identities = 51/170 (30%), Positives = 83/170 (48%), Gaps = 11/170 (6%)
Query: 94 NQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRP 153
N K + + SSS+ D+ R S + R +S S + ++ RS SP +R R
Sbjct: 358 NPSKERSHSHSRSSSKERDH-RGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRS 416
Query: 154 R-------RSRSHSDND-RFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKT 205
R RSRS S N R R+RS +++ SRSRS ++ + +++S +++ +++
Sbjct: 417 RSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRS 476
Query: 206 RGTSKTDSKTHYKSGSRYEKESRKKEPPRSKS--QSRSQSRSRSKSRSRS 253
R SK + S S+ R + P + + QSRS S+ R RSRS
Sbjct: 477 RSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRS 526
Score = 58.2 bits (139), Expect = 7e-09
Identities = 50/202 (24%), Positives = 90/202 (44%), Gaps = 40/202 (19%)
Query: 92 TPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSR--- 148
TP +++ R +S + + SR +SY R R+ +R + R+ S ++ R
Sbjct: 141 TPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPG 200
Query: 149 ---------------------PTGRPRRSRSHSDNDRFKHRNRSF------SRSKSNSRS 181
PTG P + +S + + + +S+ SR KS S +
Sbjct: 201 GSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPT 260
Query: 182 RSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSR- 240
S+ K +A +RSR SH+++R ++ S + ++ SR S K+ R++S++R
Sbjct: 261 EMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRK 320
Query: 241 ---------SQSRSRSKSRSRS 253
SQSRS SK +S++
Sbjct: 321 GILSQMGRHSQSRSHSKGKSQN 342
Score = 54.7 bits (130), Expect = 8e-08
Identities = 40/171 (23%), Positives = 78/171 (45%), Gaps = 6/171 (3%)
Query: 92 TPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTG 151
TP+ K + + S + D+ + +SY + SR +SYSP
Sbjct: 213 TPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSRE------KSYSPTEMSSRV 266
Query: 152 RPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKT 211
+ S + ++RS RS+S S+ R+ S+ + ++ SR+ S T+ S+
Sbjct: 267 KSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQM 326
Query: 212 DSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSSGH 262
+ +S S+ + +++ + P R +S + S++ S+ +S S S +S K H
Sbjct: 327 GRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDH 377
Score = 39.3 bits (90), Expect = 0.004
Identities = 33/114 (28%), Positives = 50/114 (43%), Gaps = 7/114 (6%)
Query: 147 SRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTR 206
S + P RS + ++ S S SKS + +K P ++SR RS + T +R
Sbjct: 34 STKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSR 93
Query: 207 -----GTSKTDSKTHYKSGSRYEKESRKKEPPR--SKSQSRSQSRSRSKSRSRS 253
TSK + + R SR + P R S+S RS SR+ + R R+
Sbjct: 94 VSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRT 147
Score = 37.0 bits (84), Expect = 0.017
Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 1/120 (0%)
Query: 144 PRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHT 203
P + + T +RS RN S S S S + ++ + SRSR S
Sbjct: 29 PASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKA 88
Query: 204 KTRGTSKTDSKTHYKS-GSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSSGH 262
+T TD++T S S R+ R ++ R SRS +S SR+ T + H
Sbjct: 89 RTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTH 148
Score = 35.4 bits (80), Expect = 0.051
Identities = 42/151 (27%), Positives = 63/151 (41%), Gaps = 18/151 (11%)
Query: 90 RKTPNQMKAKEGRNVYSSSRYDDYDR---------YRRSRSRSYERRRSRSRSFDYNYRR 140
R+ + K +E R SSS D+ R Y R R+ S E+ SRSR+
Sbjct: 570 RRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNH 629
Query: 141 SYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSA 200
S S +S+ + S S R RS +R+ S S++R+ S K + S S
Sbjct: 630 SQSRTSSKES-----DPSQSTVPRSPDWKRSPTRTSSLSQNRTPS--KTSSHSPSTFPSG 682
Query: 201 SHTKTRGTSKTDSKTHYKS--GSRYEKESRK 229
T ++ S+ D+ T + G R S K
Sbjct: 683 GQTLSQDDSQADATTSKATLPGERSSSSSSK 713
Score = 32.0 bits (71), Expect = 0.56
Identities = 25/101 (24%), Positives = 45/101 (44%), Gaps = 1/101 (0%)
Query: 160 SDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKS 219
S R + S + S S+ + P KS + + S T+ + +S S
Sbjct: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMS-PS 60
Query: 220 GSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSS 260
S+ K + K P ++ SRS+ RS++++ SR T ++S
Sbjct: 61 SSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTS 101
>gi|9558733 transformer-2 alpha [Homo sapiens]
Length = 282
Score = 75.5 bits (184), Expect = 4e-14
Identities = 62/176 (35%), Positives = 79/176 (44%), Gaps = 38/176 (21%)
Query: 2 SRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDV 61
SR PNT L V ++ T DLR F RYGP+ V V D T R RGFA+V FE +
Sbjct: 111 SRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERI 170
Query: 62 RDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSS-------------- 107
D+++A+ + + GR+I + ++ R GR +S
Sbjct: 171 DDSKEAMERANGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTHSGGGGGGGGGGGGGGG 230
Query: 108 ----------------SRYDDYD-RY-RRSRSRSYERRRSRSRSFDYNYRRSYSPR 145
RY+DYD RY RRS S Y R RSRSRS RSYSPR
Sbjct: 231 GRRRDSYYDRGYDRGYDRYEDYDYRYRRRSPSPYYSRYRSRSRS------RSYSPR 280
Score = 45.1 bits (105), Expect = 6e-05
Identities = 32/104 (30%), Positives = 55/104 (52%), Gaps = 2/104 (1%)
Query: 158 SHSDNDRFKHR-NRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTH 216
S + + F+ R +RS S+S + + +R KS+ + ++ SR S + +R SK+ S++
Sbjct: 2 SDVEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRSR 61
Query: 217 YKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSS 260
S RY + R +S+SRS + + RSRS SP S+
Sbjct: 62 RHSHRRYTRSRSHSHSHRRRSRSRSYTPEYRRRRSRS-HSPMSN 104
Score = 45.1 bits (105), Expect = 6e-05
Identities = 42/129 (32%), Positives = 60/129 (46%), Gaps = 30/129 (23%)
Query: 123 SYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSR 182
++E R SRS+S PTG P R +S S + +RS SR +S S
Sbjct: 8 NFEGRESRSQS-------------KSPTGTPARVKSES-----RSGSRSPSRVSKHSESH 49
Query: 183 SKSQPKKEMKAKSRSRSASHTKTRGT-SKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRS 241
S+S ++KSRSRS H+ R T S++ S +H R SR P + +SRS
Sbjct: 50 SRS------RSKSRSRSRRHSHRRYTRSRSHSHSH-----RRRSRSRSYTPEYRRRRSRS 98
Query: 242 QSRSRSKSR 250
S ++ R
Sbjct: 99 HSPMSNRRR 107
Score = 43.9 bits (102), Expect = 1e-04
Identities = 27/59 (45%), Positives = 35/59 (59%), Gaps = 1/59 (1%)
Query: 106 SSSRYDDYDRYRRSRSRSYE-RRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDND 163
S SR + RY RSRS S+ RRRSRSRS+ YRR S +S + R R + S ++ D
Sbjct: 58 SRSRRHSHRRYTRSRSHSHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRANPD 116
Score = 42.7 bits (99), Expect = 3e-04
Identities = 35/108 (32%), Positives = 52/108 (48%), Gaps = 18/108 (16%)
Query: 92 TPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTG 151
TP ++K++ S SR + S S S R +SRSRS +++RR
Sbjct: 24 TPARVKSESRSGSRSPSRVS-----KHSESHSRSRSKSRSRSRRHSHRRY---------- 68
Query: 152 RPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRS 199
RSRSHS + R + R+RS++ RSRS S P + + SR+
Sbjct: 69 --TRSRSHSHSHRRRSRSRSYTPEYRRRRSRSHS-PMSNRRRHTGSRA 113
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 75.1 bits (183), Expect = 6e-14
Identities = 64/163 (39%), Positives = 87/163 (53%), Gaps = 19/163 (11%)
Query: 106 SSSRYDDYDRYRRSRSR-SYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDR 164
S SR R RRSRSR S RRRSRSR+ + RRS R+ P RRSRS + R
Sbjct: 1888 SRSRTSPVSR-RRSRSRTSVTRRRSRSRASPVSRRRS---RSRTPPVTRRRSRSRTPTTR 1943
Query: 165 FKHRN--------RSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTH 216
+ R+ RS SR+ +R RS+S+ + +SRSR++ T+ R S+T T
Sbjct: 1944 RRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTR 2003
Query: 217 YKSGSR----YEKESRKKEPP--RSKSQSRSQSRSRSKSRSRS 253
+S SR + SR + PP R +S+SR+ R +SRSRS
Sbjct: 2004 RRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRS 2046
Score = 70.1 bits (170), Expect = 2e-12
Identities = 56/177 (31%), Positives = 92/177 (51%), Gaps = 9/177 (5%)
Query: 90 RKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSR-SYERRRSRSRSFDYNYRRSYSPRNSR 148
R+ ++ +++ R S Y R+ SR S RRR RSR+ + +RS S +
Sbjct: 1800 RRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPA 1859
Query: 149 PTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSR----SRSKSQPKKEM-KAKSRSRSASHT 203
P R R S + + R + R SR +S SR SR +S+ + + + +SRSR++ +
Sbjct: 1860 PWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVS 1919
Query: 204 KTRGTSKTDSKTHYKSGSR---YEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSP 257
+ R S+T T +S SR + SR + PP ++ +SRS++ ++ RSRS TSP
Sbjct: 1920 RRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSP 1976
Score = 69.7 bits (169), Expect = 2e-12
Identities = 63/186 (33%), Positives = 90/186 (48%), Gaps = 24/186 (12%)
Query: 91 KTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRN---- 146
+TP + +++ SR R RSRSR+ RRRSR+RS RS SP
Sbjct: 587 RTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGR 646
Query: 147 --SRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRS-----KSQPKKEMKAKSRSRS 199
SR R RSRS + R + R+R+ +R SRSR+ +S+ + + +SRSRS
Sbjct: 647 SRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRS 706
Query: 200 -----ASHTKT---RGTSKTDSKTHYKSGSRYEKESRKKEPPRSKS-----QSRSQSRSR 246
SH++T RG S + S+ KS + + P KS +SRS S R
Sbjct: 707 LVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPR 766
Query: 247 SKSRSR 252
SK++SR
Sbjct: 767 SKAKSR 772
Score = 69.3 bits (168), Expect = 3e-12
Identities = 57/148 (38%), Positives = 76/148 (51%), Gaps = 11/148 (7%)
Query: 114 DRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFS 173
DR S+S S R+RSRSRS RR S +SR R SR+ S R R S
Sbjct: 1789 DRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSS------RRRRGRS 1842
Query: 174 RSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPP 233
R+ SR RS+S+ +SRSR++ T R S+T + +S SR SR++
Sbjct: 1843 RTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRS 1902
Query: 234 RSKSQSRSQSRSR----SKSRSRSWTSP 257
R+ S +R +SRSR S+ RSRS T P
Sbjct: 1903 RT-SVTRRRSRSRASPVSRRRSRSRTPP 1929
Score = 68.6 bits (166), Expect = 5e-12
Identities = 62/168 (36%), Positives = 84/168 (50%), Gaps = 16/168 (9%)
Query: 98 AKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRN---SRPTGRPR 154
AK GR SR + SRSRS + RRSRS + RS SP+ SR RP
Sbjct: 490 AKRGR-----SRSRTPTKRGHSRSRSPQWRRSRSAQ---RWGRSRSPQRRGRSRSPQRPG 541
Query: 155 RSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSK 214
SRS N + + R+RS R +S+SRS + + R RS S T R S++ +
Sbjct: 542 WSRSR--NTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTP 599
Query: 215 THYKSGSR---YEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKS 259
T +S SR SR + P R +S++RS R RS+SRS + S +S
Sbjct: 600 TRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRS 647
Score = 65.5 bits (158), Expect = 5e-11
Identities = 53/137 (38%), Positives = 72/137 (52%), Gaps = 7/137 (5%)
Query: 117 RRSRSRS-YERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRS 175
RRSRSR+ RRRSRSR+ RRS R+ P RRSRS + R RS SR+
Sbjct: 1933 RRSRSRTPTTRRRSRSRTPPVTRRRS---RSRTPPVTRRRSRSRTSPIT---RRRSRSRT 1986
Query: 176 KSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRS 235
+R RS+S+ + +SRSR++ T+ R S+T +S SR RK+ RS
Sbjct: 1987 SPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRS 2046
Query: 236 KSQSRSQSRSRSKSRSR 252
R +SRSR+ +R
Sbjct: 2047 PLAIRRRSRSRTPRTAR 2063
Score = 63.9 bits (154), Expect = 1e-10
Identities = 59/170 (34%), Positives = 77/170 (45%), Gaps = 18/170 (10%)
Query: 97 KAKEGRNVYSSSRYDDYDRYRRSRSRSYERR---RSRSRSFDYNYRRSYSPRNSRPTGRP 153
K++ R S+S RR RS S + R RSRSRS R R +R
Sbjct: 1738 KSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRS------RREKTRTTR----- 1786
Query: 154 RRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDS 213
RR RS S + R RS SRS+ R R S A+ S S + RG S+T
Sbjct: 1787 RRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPP 1846
Query: 214 KTHYKSGSRYE----KESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKS 259
+ +S SR K SR + P + +SRS++ S+ RSRS TSP S
Sbjct: 1847 TSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVS 1896
Score = 63.5 bits (153), Expect = 2e-10
Identities = 60/166 (36%), Positives = 80/166 (48%), Gaps = 10/166 (6%)
Query: 106 SSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRF 165
S SR R RSR+ RRRSRSR+ RRS S R S T R RSR+ R
Sbjct: 1935 SRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRS-RTSPITRRRSRSRTSPVTRRR 1993
Query: 166 KH-------RNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYK 218
R RS SR+ +R RS+S+ ++ +SRSR+ + R S++ +
Sbjct: 1994 SRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRR 2053
Query: 219 SGSRYEKESR-KKEPPRSKSQSRSQSRSRSKS-RSRSWTSPKSSGH 262
S SR + +R K+ RS R +S S S S RSRS T P + H
Sbjct: 2054 SRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNH 2099
Score = 62.4 bits (150), Expect = 4e-10
Identities = 55/152 (36%), Positives = 75/152 (49%), Gaps = 11/152 (7%)
Query: 117 RRSRSRSYERRRSRSRSFDYNYR---RSYSP------RNSRPTGRPRRSRSHSDNDRFKH 167
RRSRSRS RR RSRS R RS +P R+ P R RSRS + R +
Sbjct: 633 RRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRS 692
Query: 168 RNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKES 227
R+R+ R +S SRS + + R RS S ++ + S+T + + S K+S
Sbjct: 693 RSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKS 752
Query: 228 R-KKEPPRSKSQSRSQSRSR-SKSRSRSWTSP 257
R RS S RS+++SR S RS S +SP
Sbjct: 753 RISSRRSRSLSSPRSKAKSRLSLRRSLSGSSP 784
Score = 61.6 bits (148), Expect = 7e-10
Identities = 53/145 (36%), Positives = 77/145 (53%), Gaps = 15/145 (10%)
Query: 117 RRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRP-RRSRSHSDNDRFKHRNRSFSRS 175
RR RSRS RR RSRS RS R + P RR RS S ++R K+++R+ S
Sbjct: 688 RRGRSRSRTPRRGRSRS------RSLVRRGRSHSRTPQRRGRSGSSSER-KNKSRT---S 737
Query: 176 KSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRS 235
+ SRS S + KK + RSRS S +++ S+ + S K+ + P RS
Sbjct: 738 QRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRS 797
Query: 236 KSQSRSQSRSRSKS---RSRSWTSP 257
+S S SQ +++S++ RSRS +SP
Sbjct: 798 RSGS-SQPKAKSRTPPRRSRSSSSP 821
Score = 61.2 bits (147), Expect = 9e-10
Identities = 66/204 (32%), Positives = 92/204 (45%), Gaps = 35/204 (17%)
Query: 86 AQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYR---RSY 142
A+ ++ ++ A+ GR SR R RSRSR+ RR RSRS R RS
Sbjct: 641 ARRSGRSRSRTPARRGR-----SRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSR 695
Query: 143 SPRNSRPTGRP--RRSRSHSDNDRFKHRNRSFSRSKSNSRS---RSKSQPKKEMK----- 192
+PR R R RR RSHS + + R+ S S K+ SR+ RS+S EMK
Sbjct: 696 TPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRIS 755
Query: 193 -----------AKSRSRSASHTKTRGTS---KTDSKT---HYKSGSRYEKESRKKEPPRS 235
+K++SR + G+S K S+T +SGS K + P RS
Sbjct: 756 SRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRS 815
Query: 236 KSQSRSQSRSRSKSRSRSWTSPKS 259
+S S + +SK+ SR S S
Sbjct: 816 RSSSSPPPKQKSKTPSRQSHSSSS 839
Score = 60.1 bits (144), Expect = 2e-09
Identities = 61/177 (34%), Positives = 84/177 (47%), Gaps = 16/177 (9%)
Query: 90 RKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERR-RSRSRSFDYNYRRSYSP--RN 146
R T + +++ R S SR RSRSR+ RR RSRSR+ RS +P R
Sbjct: 546 RNTQRRGRSRSARRGRSHSRSPA--TRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRR 603
Query: 147 SRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRS-----RSAS 201
SR RR RS S R R RS +RS RSRS+S ++ +++SR+ RS S
Sbjct: 604 SRSRTPARRGRSRS---RTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRS 660
Query: 202 HTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRS---KSRSRSWT 255
T R +SG + ++ RS++ R +SRSRS + RS S T
Sbjct: 661 RTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRT 717
Score = 55.5 bits (132), Expect = 5e-08
Identities = 51/156 (32%), Positives = 70/156 (44%), Gaps = 12/156 (7%)
Query: 106 SSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRF 165
SS + R R SRS +++SR+ SP +R RRSRS S +
Sbjct: 1657 SSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPET 1716
Query: 166 KHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTS--------KTDSKTHY 217
+ R R S S S +P ++ ++ R RSAS +T+ TS K
Sbjct: 1717 RSRTPPRHR---RSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRS 1773
Query: 218 KSGSRYEKESRKKEPPRS-KSQSRSQSRSRSKSRSR 252
+S SR EK + RS SQS S+ R RS+SRSR
Sbjct: 1774 RSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSR 1809
Score = 51.6 bits (122), Expect = 7e-07
Identities = 55/193 (28%), Positives = 79/193 (40%), Gaps = 33/193 (17%)
Query: 91 KTPNQMKAKEGRNVYSSSRYDDYDRY--RRSRSRSYERRRSRSRSFDYNYRRSYS---PR 145
+TP + +++ G SS D R RRSRS S + + R+ S S P+
Sbjct: 1570 RTPLRQRSRSG----SSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPK 1625
Query: 146 NSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKT 205
P PRRSRS S + + R S S+S S P K A+ SRS+ KT
Sbjct: 1626 APAPRALPRRSRSGSSS-----KGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKT 1680
Query: 206 RGTSKTDSKTHYKSGSRYEK--------------ESRKKEPPR-----SKSQSRSQSRSR 246
+ + ++ S K E+R + PPR S S +SR
Sbjct: 1681 KSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSR 1740
Query: 247 SKSRSRSWTSPKS 259
S R RS +SP++
Sbjct: 1741 SSRRRRSASSPRT 1753
Score = 50.4 bits (119), Expect = 2e-06
Identities = 50/144 (34%), Positives = 70/144 (48%), Gaps = 17/144 (11%)
Query: 117 RRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSK 176
RRSRS S +RSR+ +RRS S + P + R SR + R+ S R+K
Sbjct: 1705 RRSRSAS-SSPETRSRT-PPRHRRSPSVSSPEPAEKSRSSR--------RRRSASSPRTK 1754
Query: 177 SNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSK 236
+ SR PK +SRSRS KTR T + D +SGS + SR+++ RS+
Sbjct: 1755 TTSRRGRSPSPKPRGLQRSRSRSRRE-KTRTTRRRD-----RSGSS-QSTSRRRQRSRSR 1807
Query: 237 SQSRSQSRSRSKSRSRSWTSPKSS 260
S+ + R S SRS +SS
Sbjct: 1808 SRVTRRRRGGSGYHSRSPARQESS 1831
Score = 50.1 bits (118), Expect = 2e-06
Identities = 30/89 (33%), Positives = 46/89 (51%), Gaps = 3/89 (3%)
Query: 171 SFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKK 230
S R S+SRS + Q KK+ K RS S + R K+ K ++S S +K +
Sbjct: 172 SLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRS 231
Query: 231 EPPRSKSQSRSQSRSRSKSRSRSWTSPKS 259
P+SK +S+ + R RS+S + +PKS
Sbjct: 232 PTPKSKRKSKDKKRKRSRSTT---PAPKS 257
Score = 49.3 bits (116), Expect = 3e-06
Identities = 53/142 (37%), Positives = 65/142 (45%), Gaps = 26/142 (18%)
Query: 117 RRSRSRS--YERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSR 174
RRSRSR+ RRRSRSR+ RRS R+ P RRSRS + R RS SR
Sbjct: 1992 RRSRSRTSPVTRRRSRSRTSPVTRRRS---RSRTPPAIRRRSRSRTP---LLPRKRSRSR 2045
Query: 175 SKSNSRSRSKSQPKKEMKAKS---------RSRSASHTKT-RGTSKTDSKTHYKSGSRYE 224
S R RS+S+ + + K R RSAS + + R S T T SGSR
Sbjct: 2046 SPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSR-- 2103
Query: 225 KESRKKEPPRSKSQSRSQSRSR 246
PP + + SR SR
Sbjct: 2104 ------TPPVALNSSRMSCFSR 2119
Score = 48.1 bits (113), Expect = 8e-06
Identities = 43/151 (28%), Positives = 69/151 (45%), Gaps = 15/151 (9%)
Query: 119 SRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSN 178
S++RS+ R + R +S + R S T + RSRS + R S SRS
Sbjct: 459 SKNRSHGRAK-RDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKR----GHSRSRSPQW 513
Query: 179 SRSRSKSQPKKEMKAKSRSRSAS----------HTKTRGTSKTDSKTHYKSGSRYEKESR 228
RSRS + + + R RS S +T+ RG S++ + S S +
Sbjct: 514 RRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRS 573
Query: 229 KKEPPRSKSQSRSQSRSRSKSRSRSWTSPKS 259
+ P + +SRS++ +R +SRSR+ T +S
Sbjct: 574 RSRTPARRGRSRSRTPARRRSRSRTPTRRRS 604
Score = 45.4 bits (106), Expect = 5e-05
Identities = 50/146 (34%), Positives = 60/146 (41%), Gaps = 14/146 (9%)
Query: 117 RRSRSRS--YERRRSRSRSFDYNYRRSYSPRNSRPTGRPR-------RSRSHSDNDRFKH 167
RRSRSR+ RRRSRSR+ RRS S P R R R RS S R
Sbjct: 2004 RRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTAR 2063
Query: 168 RNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKES 227
RS +RS R RS S + RSRSA+ TR S + + + SR S
Sbjct: 2064 GKRSLTRSPPAIRRRSASG-----SSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFS 2118
Query: 228 RKKEPPRSKSQSRSQSRSRSKSRSRS 253
R P + RS SR+
Sbjct: 2119 RPSMSPTPLDRCRSPGMLEPLGSSRT 2144
Score = 44.3 bits (103), Expect = 1e-04
Identities = 45/166 (27%), Positives = 72/166 (43%), Gaps = 30/166 (18%)
Query: 106 SSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSR-PTGRPRRSRSHSDNDR 164
SSS + ++ + + RRS S SPR R + + ++ RS S++ +
Sbjct: 177 SSSSRSPTPKQKKKKKKKDRGRRSESS----------SPRRERKKSSKKKKHRSESESKK 226
Query: 165 FKHRN---RSFSRSKSNSRSRSKS-QPKKEMKAKSRSRSASHTKTRGTSKTDS-----KT 215
KHR+ +S +SK R RS+S P + + RS SA + TS++ S KT
Sbjct: 227 RKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKT 286
Query: 216 HY----------KSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRS 251
H SG R E ++ EP + +Q S + +K S
Sbjct: 287 HTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPS 332
Score = 43.5 bits (101), Expect = 2e-04
Identities = 45/169 (26%), Positives = 70/169 (41%), Gaps = 25/169 (14%)
Query: 115 RYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSR 174
R R S + S E + R+ R SP +G P R + K R+ SR
Sbjct: 1416 RERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSR 1475
Query: 175 SKSNS---------------RSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKT---- 215
+S RSRS S P+ K + R S +++ KT ++T
Sbjct: 1476 GRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQ 1535
Query: 216 HYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKS------RSRSWTSPK 258
+SGS E + + P+ +S+S S S++K+ RSRS +SP+
Sbjct: 1536 RSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPE 1584
Score = 41.2 bits (95), Expect = 0.001
Identities = 44/192 (22%), Positives = 76/192 (39%), Gaps = 19/192 (9%)
Query: 84 QFAQGDRKTPNQMKAKEG--RNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRS 141
Q A+ + K +++A G + S +D R R ++ + E + S + + RS
Sbjct: 123 QLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRS 182
Query: 142 YSPRNSRP-----------TGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKE 190
+P+ + + PRR R S + KHR+ S S+ + + KS+ K +
Sbjct: 183 PTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKK-KHRSESESKKRKHRSPTPKSKRKSK 241
Query: 191 MKAKSRSRSA-----SHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRS 245
K + RSRS S R TS + + S SR + K +S S +
Sbjct: 242 DKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASG 301
Query: 246 RSKSRSRSWTSP 257
R ++ P
Sbjct: 302 RRGEGDAPFSEP 313
Score = 41.2 bits (95), Expect = 0.001
Identities = 47/163 (28%), Positives = 70/163 (42%), Gaps = 31/163 (19%)
Query: 117 RRSRSRSYERRRSR-SRSFDYNYRRSYSPRNSRPTGRP--RRSRSHSDNDRFKHRNRSFS 173
+RSRS S + + S S SP + T P +RSRS S + S
Sbjct: 1535 QRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPR 1594
Query: 174 RSKSNSRSRSKSQPKKEMKAKS------------------RSRSASHTKTRGTSKTDSKT 215
RS+S S K +P+ +A+S RSRS S +K RG S S +
Sbjct: 1595 RSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSS 1654
Query: 216 HYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPK 258
ES + PP+S++ +R SRS + +++S T P+
Sbjct: 1655 ---------TESSPEHPPKSRT-ARRGSRSSPEPKTKSRTPPR 1687
Score = 40.4 bits (93), Expect = 0.002
Identities = 48/153 (31%), Positives = 68/153 (44%), Gaps = 25/153 (16%)
Query: 117 RRSRSRS--YERRRSRSRSFDYNYRRSYS--PRNSR--------PTGRPRRSRSHSDNDR 164
RRSRSR+ R+RSRSRS RRS S PR +R P RRS S S +DR
Sbjct: 2028 RRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDR 2087
Query: 165 FKH------RNRSFSRSK----SNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSK 214
+ RN S SR+ ++SR S+P R RS + G+S+T
Sbjct: 2088 SRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMS 2147
Query: 215 THYKSGSRYEKESRKKEPPRSKS---QSRSQSR 244
++G + P ++ ++ +QSR
Sbjct: 2148 VLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSR 2180
Score = 38.5 bits (88), Expect = 0.006
Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 4/92 (4%)
Query: 168 RNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSR-YEKE 226
R R S S S+S S S S + S S S+S + + +S + S + K G + K
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662
Query: 227 SRKKEPPRSKSQSRSQSR---SRSKSRSRSWT 255
+ K+PP + +SRS + S SRS S++
Sbjct: 2663 ASPKKPPPGERRSRSPRKPIDSLRDSRSLSYS 2694
Score = 38.1 bits (87), Expect = 0.008
Identities = 44/144 (30%), Positives = 64/144 (44%), Gaps = 30/144 (20%)
Query: 141 SYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFS-RSKSNS--------RSRSKSQPKKEM 191
S SP + +P P R S + K+R+ + R KS+S RSRS + K
Sbjct: 435 SSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAK--- 491
Query: 192 KAKSRSRSASHTKTRGTSKTDSKTHYKSGSRY--------EKESRKKEPPR------SKS 237
+ RSRS + TK RG S++ S +S S ++ R + P R +
Sbjct: 492 --RGRSRSRTPTK-RGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNT 548
Query: 238 QSRSQSRSRSKSRSRSWTSPKSSG 261
Q R +SRS + RS S SP + G
Sbjct: 549 QRRGRSRSARRGRSHS-RSPATRG 571
Score = 37.7 bits (86), Expect = 0.010
Identities = 44/172 (25%), Positives = 72/172 (41%), Gaps = 10/172 (5%)
Query: 91 KTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPT 150
K +Q + R+ S + RRSRS S + +S++ S SP +
Sbjct: 787 KQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKS 846
Query: 151 GRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSR--SASHTKTRGT 208
G P R S + +S + + RS +S P E+K+++ SR + + R
Sbjct: 847 GTPPRQGSITSPQA---NEQSVTPQR---RSCFESSPDPELKSRTPSRHSCSGSSPPRVK 900
Query: 209 SKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSS 260
S T + S + + + PR +S S S S S S+ SR T+P+ S
Sbjct: 901 SSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSR--TTPRRS 950
Score = 37.0 bits (84), Expect = 0.017
Identities = 45/167 (26%), Positives = 68/167 (40%), Gaps = 25/167 (14%)
Query: 117 RRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRF--------KHR 168
RRSRS S R S + + SP P R RS D+ + R
Sbjct: 1437 RRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPR 1496
Query: 169 NRSFSRSKSNS------RSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSR 222
+RS S + N+ R RS S+ + K +R+ +++ + + D K R
Sbjct: 1497 SRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQER 1556
Query: 223 YEKES------RKKEPPRSKSQSRSQSRSRSKS-----RSRSWTSPK 258
E +S + + P R +S+S S SKS RSRS +SP+
Sbjct: 1557 SESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPE 1603
Score = 36.6 bits (83), Expect = 0.023
Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 2/115 (1%)
Query: 140 RSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRS 199
+S S +S P+ +P + H+ + + S S S+ + +AK R +S
Sbjct: 414 QSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAK-RDKS 472
Query: 200 ASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSK-SRSRS 253
SHT +R ++ S K G + K+ RS+S +SRS + RSRS
Sbjct: 473 HSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRS 527
Score = 35.4 bits (80), Expect = 0.051
Identities = 39/156 (25%), Positives = 50/156 (32%), Gaps = 33/156 (21%)
Query: 140 RSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRS 199
R P P R RRS S S + + S S S S+S S S S + S S S
Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
Query: 200 ASHTKTRGTSKTDSKTHYKSGSRYEKESRK-----------------------KEPPRSK 236
+ + K S G R + RK + PR +
Sbjct: 2651 PAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQ 2710
Query: 237 SQSRSQ----------SRSRSKSRSRSWTSPKSSGH 262
S S+ SRS S R R SP+ H
Sbjct: 2711 QSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRH 2746
Score = 33.5 bits (75), Expect = 0.19
Identities = 27/100 (27%), Positives = 41/100 (41%), Gaps = 16/100 (16%)
Query: 177 SNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSK----------------THYKSG 220
+ R S S + S S S+S + + G+S +DS+ + +
Sbjct: 2527 AKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAP 2586
Query: 221 SRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSS 260
+E R EP +K + RS S S S S S S +S SS
Sbjct: 2587 KEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSS 2626
Score = 32.7 bits (73), Expect = 0.33
Identities = 30/84 (35%), Positives = 36/84 (42%), Gaps = 8/84 (9%)
Query: 117 RRSRSRSY---ERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFS 173
RRSRS R SRS S+ RR SP+ S PR +S S + R S
Sbjct: 2673 RRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPS-----PRDQQSSSSERGSRRGQRGDS 2727
Query: 174 RSKSNSRSRSKSQPKKEMKAKSRS 197
RS S+ R R P+ SRS
Sbjct: 2728 RSPSHKRRRETPSPRPMRHRSSRS 2751
Score = 32.3 bits (72), Expect = 0.43
Identities = 43/164 (26%), Positives = 62/164 (37%), Gaps = 21/164 (12%)
Query: 117 RRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFK--------HR 168
RRS S +SR+ + SP + + PR+S S S + + K R
Sbjct: 869 RRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQR 928
Query: 169 NRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTR----GTSKTDSK---------T 215
+ S S S S SR S++ P++ S S R G+S D+K +
Sbjct: 929 SHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQS 988
Query: 216 HYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKS 259
H S S Y K + P S S S+S S + P S
Sbjct: 989 HSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGS 1032
Score = 31.2 bits (69), Expect = 0.96
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 4/83 (4%)
Query: 139 RRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSR 198
RRS SPR + R RS S+S +R + + R + +S S S+ + + SR
Sbjct: 2673 RRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQ----RGDSR 2728
Query: 199 SASHTKTRGTSKTDSKTHYKSGS 221
S SH + R T H S S
Sbjct: 2729 SPSHKRRRETPSPRPMRHRSSRS 2751
>gi|4502847 cold inducible RNA binding protein [Homo sapiens]
Length = 172
Score = 74.7 bits (182), Expect = 8e-14
Identities = 51/159 (32%), Positives = 75/159 (47%), Gaps = 7/159 (4%)
Query: 12 LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
LFV ++ DT + L + F +YG I +V V D T+R RGF +V FE++ DA+DA+ +
Sbjct: 8 LFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAM 67
Query: 72 DRKWICGRQIEIQFAQGDRKTPNQMK-----AKEGRNVYSSSRYDDYDRYRRSRSRSYER 126
+ K + GRQI + Q + + N+ + + GR + R R R Y
Sbjct: 68 NGKSVDGRQIRVD--QAGKSSDNRSRGYRGGSAGGRGFFRGGRGRGRGFSRGGGDRGYGG 125
Query: 127 RRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRF 165
R SRS Y R Y S+ G RS S D +
Sbjct: 126 NRFESRSGGYGGSRDYYSSRSQSGGYSDRSSGGSYRDSY 164
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 72.8 bits (177), Expect = 3e-13
Identities = 58/178 (32%), Positives = 91/178 (51%), Gaps = 13/178 (7%)
Query: 87 QGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRN 146
+GDR+ ++ + KE N R DYD+ R R ER RSR RS + R +
Sbjct: 346 KGDRRDRDREREKE--NERGRRRDRDYDK-ERGNEREKERERSRERSKEQRSRGEVEEKK 402
Query: 147 SRPTGRPRRSRSHS-DNDRFKHRNRSFSRS-KSNSRSRSKSQPKKEMKAKSRSRSASHTK 204
+ RR R D+ + K +RS SR K SRSRS++ K+ +++S+ +S+ H
Sbjct: 403 HKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRS-RSRSKEKSSKH-- 459
Query: 205 TRGTSKTDSKTHYKSGSRYE----KESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPK 258
+ SK S +SGS+ ++S+K+E SK +SR +SRS+ +S R + K
Sbjct: 460 -KNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSK 516
Score = 65.9 bits (159), Expect = 4e-11
Identities = 48/147 (32%), Positives = 74/147 (50%), Gaps = 11/147 (7%)
Query: 111 DDYDRYRRS--RSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHR 168
D DR R R E++ SRSRS + +R RN+ +RSRS S KH+
Sbjct: 406 DKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAG-----KRSRSRSKEKSSKHK 460
Query: 169 NRSFSRSKSNSRSRSKSQPKKEM--KAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKE 226
N S + KSN RSRS SQ + + K+K R S S K+R S++ ++H + S + +
Sbjct: 461 NES--KEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQ 518
Query: 227 SRKKEPPRSKSQSRSQSRSRSKSRSRS 253
S K + RS+S + + K++ +
Sbjct: 519 SDKHDRRRSQSIEQESQEKQHKNKDET 545
Score = 65.5 bits (158), Expect = 5e-11
Identities = 58/175 (33%), Positives = 83/175 (47%), Gaps = 27/175 (15%)
Query: 95 QMKAKEGRNVYSSSRYDDYD-RYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRP 153
+ +AKE SR D RRSRSR ER RSRSRS R+ + R
Sbjct: 305 EREAKEREKERRRSRSIDRGLERRRSRSR--ERHRSRSRS-----------RDRKGDRRD 351
Query: 154 RRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDS 213
R +N+R + R+R + + + N R + + + ++ K + RSR K K D
Sbjct: 352 RDREREKENERGRRRDRDYDKERGNEREKERERSRERSK-EQRSRGEVEEKKHKEDKDDR 410
Query: 214 KTHYKSGSRYEKESRKKEPPRSKSQSRS---QSRSRSKS---RSRSWTSPKSSGH 262
+ R +K KKE S+S+SR +SRSRS++ RSRS + KSS H
Sbjct: 411 R------HRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKH 459
Score = 65.5 bits (158), Expect = 5e-11
Identities = 55/178 (30%), Positives = 80/178 (44%), Gaps = 22/178 (12%)
Query: 97 KAKEGRNVYSSSRYDDYDRYRRSRSRSYE--RRRSRSRSFD--YNYRRSYSPRNSRPTGR 152
+++E S SR DR R R R E R R R R +D R SR +
Sbjct: 331 RSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSK 390
Query: 153 PRRSRSH-------SDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSA----- 200
+RSR D D +HR+ K SRS+S+ +K +++SRSR+A
Sbjct: 391 EQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKH-RSRSRSRNAGKRSR 449
Query: 201 -----SHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRS 253
+K + SK S +SGS+ +S +K R S S+ +SR RS+S+ RS
Sbjct: 450 SRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERS 507
Score = 58.5 bits (140), Expect = 6e-09
Identities = 48/134 (35%), Positives = 64/134 (47%), Gaps = 15/134 (11%)
Query: 122 RSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSR--SKSNS 179
R ERRRSRS RRS SPR S PRRSRS S + R H + SF R +
Sbjct: 253 RHVERRRSRSP------RRSLSPRRS-----PRRSRSRS-HHREGHGSSSFDRELEREKE 300
Query: 180 RSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEK-ESRKKEPPRSKSQ 238
R R + + K+ K + RSRS R S++ + +S SR K + R ++ R K
Sbjct: 301 RQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKEN 360
Query: 239 SRSQSRSRSKSRSR 252
R + R R + R
Sbjct: 361 ERGRRRDRDYDKER 374
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 72.0 bits (175), Expect = 5e-13
Identities = 55/160 (34%), Positives = 82/160 (51%), Gaps = 13/160 (8%)
Query: 95 QMKAKEGRNVYSSSRYDDYDRYRRSRSRSY------ERRRSRSRSFDYNYRRSYSPRNSR 148
+ K + R D +R +RSRSRS +RR SRSR D+ RS R SR
Sbjct: 269 ERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSR--DHKRSRSRERRRSR 326
Query: 149 PTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGT 208
R RRSRSH ++R KHR+RS R +S SR R + + + + + + R + + RG+
Sbjct: 327 SRDR-RRSRSHDRSER-KHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGS 384
Query: 209 SKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSK 248
D K+ KSGSR EK+S +S ++++ S+
Sbjct: 385 D--DKKSSVKSGSR-EKQSEDTNTESKESDTKNEVNGTSE 421
Score = 66.6 bits (161), Expect = 2e-11
Identities = 47/160 (29%), Positives = 71/160 (44%), Gaps = 7/160 (4%)
Query: 89 DRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSR 148
D + + + +E R ++ +R RR E+ R+R R RR S SR
Sbjct: 244 DERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE-----RRKRSRSRSR 298
Query: 149 PTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRG- 207
+ R R D + R+R RS+S R RS+S + E K +SRSR +K+R
Sbjct: 299 HSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDR 358
Query: 208 -TSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSR 246
+ K SK+ + R KE K+ KS +S SR +
Sbjct: 359 KSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREK 398
Score = 63.9 bits (154), Expect = 1e-10
Identities = 49/174 (28%), Positives = 76/174 (43%), Gaps = 10/174 (5%)
Query: 90 RKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRS-RSYERRRSRSRSFDYNYRRSYSPRNSR 148
+ T ++K K + R + + ++ R R ER R R R R
Sbjct: 224 KATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKER 283
Query: 149 PTGRPRRSRSHSDNDRFKHRNRSFSR--SKSNSRSRSKSQPKKEMKAKSRSRSASHTKTR 206
R RR RS S R +H +R+ R S+S RS+S+ ++ +++ R RS SH ++
Sbjct: 284 ARDRERRKRSRS---RSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSE 340
Query: 207 GTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSS 260
++ S+ +S SR RK RSKS+ R Q R + R KSS
Sbjct: 341 RKHRSRSRDRRRSKSR----DRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSS 390
Score = 40.0 bits (92), Expect = 0.002
Identities = 28/111 (25%), Positives = 44/111 (39%), Gaps = 9/111 (8%)
Query: 152 RPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKT 211
R R D K + R K R R + + K+ + + R + + + R
Sbjct: 235 RKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRER----- 289
Query: 212 DSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSSGH 262
+S SR SR + S+S+ +SRSR + RSRS +S H
Sbjct: 290 ----RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSH 336
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 72.0 bits (175), Expect = 5e-13
Identities = 55/160 (34%), Positives = 82/160 (51%), Gaps = 13/160 (8%)
Query: 95 QMKAKEGRNVYSSSRYDDYDRYRRSRSRSY------ERRRSRSRSFDYNYRRSYSPRNSR 148
+ K + R D +R +RSRSRS +RR SRSR D+ RS R SR
Sbjct: 269 ERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSR--DHKRSRSRERRRSR 326
Query: 149 PTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGT 208
R RRSRSH ++R KHR+RS R +S SR R + + + + + + R + + RG+
Sbjct: 327 SRDR-RRSRSHDRSER-KHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGS 384
Query: 209 SKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSK 248
D K+ KSGSR EK+S +S ++++ S+
Sbjct: 385 D--DKKSSVKSGSR-EKQSEDTNTESKESDTKNEVNGTSE 421
Score = 66.6 bits (161), Expect = 2e-11
Identities = 47/160 (29%), Positives = 71/160 (44%), Gaps = 7/160 (4%)
Query: 89 DRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSR 148
D + + + +E R ++ +R RR E+ R+R R RR S SR
Sbjct: 244 DERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE-----RRKRSRSRSR 298
Query: 149 PTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRG- 207
+ R R D + R+R RS+S R RS+S + E K +SRSR +K+R
Sbjct: 299 HSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDR 358
Query: 208 -TSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSR 246
+ K SK+ + R KE K+ KS +S SR +
Sbjct: 359 KSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREK 398
Score = 63.9 bits (154), Expect = 1e-10
Identities = 49/174 (28%), Positives = 76/174 (43%), Gaps = 10/174 (5%)
Query: 90 RKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRS-RSYERRRSRSRSFDYNYRRSYSPRNSR 148
+ T ++K K + R + + ++ R R ER R R R R
Sbjct: 224 KATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKER 283
Query: 149 PTGRPRRSRSHSDNDRFKHRNRSFSR--SKSNSRSRSKSQPKKEMKAKSRSRSASHTKTR 206
R RR RS S R +H +R+ R S+S RS+S+ ++ +++ R RS SH ++
Sbjct: 284 ARDRERRKRSRS---RSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSE 340
Query: 207 GTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSS 260
++ S+ +S SR RK RSKS+ R Q R + R KSS
Sbjct: 341 RKHRSRSRDRRRSKSR----DRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSS 390
Score = 40.0 bits (92), Expect = 0.002
Identities = 28/111 (25%), Positives = 44/111 (39%), Gaps = 9/111 (8%)
Query: 152 RPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKT 211
R R D K + R K R R + + K+ + + R + + + R
Sbjct: 235 RKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRER----- 289
Query: 212 DSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSSGH 262
+S SR SR + S+S+ +SRSR + RSRS +S H
Sbjct: 290 ----RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSH 336
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 71.6 bits (174), Expect = 6e-13
Identities = 45/135 (33%), Positives = 79/135 (58%), Gaps = 7/135 (5%)
Query: 120 RSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNS 179
R S ++ + +S ++N + S + GR R + S + DR K + R SR +S+S
Sbjct: 13 RHESKDKSSKKHKSEEHNDKEHSSDK-----GRERLNSSENGEDRHKRKERKSSRGRSHS 67
Query: 180 RSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRY-EKESRKKEPPRSKSQ 238
RSRS+ + + +++ R +S S ++ R S++ S+ KS SR E++ R + RS+S+
Sbjct: 68 RSRSRER-RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 126
Query: 239 SRSQSRSRSKSRSRS 253
R ++RSRS++RSRS
Sbjct: 127 HRHRTRSRSRTRSRS 141
Score = 66.2 bits (160), Expect = 3e-11
Identities = 57/160 (35%), Positives = 83/160 (51%), Gaps = 16/160 (10%)
Query: 89 DRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRN-- 146
DR + K+ GR+ +S SR R RR RSRS ER++SRSRS + RS S
Sbjct: 51 DRHKRKERKSSRGRS-HSRSR----SRERRHRSRSRERKKSRSRSRERKKSRSRSRERKK 105
Query: 147 --SRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSK----SQPKKEMKAKSRSRSA 200
SR R RR RS S R +HR+R+ SRS++ SRSR + +P++ ++ SR+ S
Sbjct: 106 SRSRSRERKRRIRSRS-RSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSP 164
Query: 201 SHTKTRGTSKTDSKTHYKSGSRYEK--ESRKKEPPRSKSQ 238
+ R T+ + + R +K E R+KE + Q
Sbjct: 165 PPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ 204
Score = 62.8 bits (151), Expect = 3e-10
Identities = 52/167 (31%), Positives = 80/167 (47%), Gaps = 20/167 (11%)
Query: 87 QGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRN 146
+ + + + +GR +SS + R+ R S R SRSRS + +R R
Sbjct: 25 KSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRER- 83
Query: 147 SRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTR 206
++SRS S +R K R+RS R KS SRSR + K+ ++++SRSRS +TR
Sbjct: 84 -------KKSRSRS-RERKKSRSRSRERKKSRSRSRER---KRRIRSRSRSRSRHRHRTR 132
Query: 207 GTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRS 253
S+T SR ++ E PR S+S S++ S R R+
Sbjct: 133 SRSRT--------RSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRN 171
Score = 47.4 bits (111), Expect = 1e-05
Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 21/110 (19%)
Query: 150 TGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTS 209
+ + +S H+D + + R S N R K + +K + +S SRS S
Sbjct: 20 SSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR------- 72
Query: 210 KTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKS 259
E+ R + R KS+SRS+ R +S+SRSR +S
Sbjct: 73 --------------ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRS 108
Score = 37.0 bits (84), Expect = 0.017
Identities = 33/134 (24%), Positives = 56/134 (41%), Gaps = 5/134 (3%)
Query: 94 NQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRP 153
++ +++E + S SR RSRSRS R R+RSRS + R R +P
Sbjct: 96 SRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFS 155
Query: 154 RRSRSHSDNDRFKHRNRSFSRSKSNSR-----SRSKSQPKKEMKAKSRSRSASHTKTRGT 208
R F+ RN + ++ +R + + Q +KEM K + + + G
Sbjct: 156 RSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAAAAATGG 215
Query: 209 SKTDSKTHYKSGSR 222
S + SG++
Sbjct: 216 SVLNVAALLASGTQ 229
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 71.2 bits (173), Expect = 8e-13
Identities = 61/181 (33%), Positives = 94/181 (51%), Gaps = 21/181 (11%)
Query: 97 KAKEGRNVYSSS----RYDDYDRYRRSRSRSYERR--------RSRSRSFDYNYRRSYSP 144
+ +E +++ S++ + ++ R+ RSRSRS RR RSRSRS ++ +S S
Sbjct: 225 RVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSR 284
Query: 145 RNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNS---RSRSKSQPKKEMKAKSRSRSAS 201
R S+ PRR RSHS + R+ S +R K + RSK+ PK A+ RSRSAS
Sbjct: 285 RRSKS---PRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTAR-RSRSAS 340
Query: 202 HTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPR-SKSQSRSQSRSRSK-SRSRSWTSPKS 259
+ R S++ +++ K S K SR P R K + + + + RS+ R RS + K
Sbjct: 341 RERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKK 400
Query: 260 S 260
S
Sbjct: 401 S 401
Score = 62.8 bits (151), Expect = 3e-10
Identities = 50/173 (28%), Positives = 87/173 (50%), Gaps = 18/173 (10%)
Query: 90 RKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRP 149
R+TP+ + + R S SR RRS S+S RRRS+S RRS+S R
Sbjct: 258 RRTPSSSRHRRSR---SRSR-------RRSHSKSRSRRRSKSP----RRRRSHSRERGRR 303
Query: 150 TGRPRRSRSHSDNDRFKHRNRSFSRSKSNS-RSRSKSQPKKEMKAKSRSRSASHTKT--R 206
+ ++R D+ K R+++ +S S + RSRS S+ ++ +++S +RS ++ R
Sbjct: 304 SRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKR 363
Query: 207 GTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQS-RSQSRSRSKSRSRSWTSPK 258
S++ S +K + +K+ + R +S S + +S+ + K R R S K
Sbjct: 364 KLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDK 416
Score = 48.5 bits (114), Expect = 6e-06
Identities = 45/173 (26%), Positives = 68/173 (39%), Gaps = 12/173 (6%)
Query: 97 KAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRS 156
K++ R S R + R R RSRS + R + + D +RS +P S T R RS
Sbjct: 280 KSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKE-DKEKKRSKTPPKSYSTARRSRS 338
Query: 157 RSHSDNDRFKHRNRSFSRSKSN--------SRSRSKSQPKKEMKAKSRSRSASHTKTRGT 208
S +R + R+RS +RS SRS S + KKE K + + R T
Sbjct: 339 ASR---ERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERST 395
Query: 209 SKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSSG 261
SK + + ES K ++ + S+ + P +G
Sbjct: 396 SKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETG 448
Score = 42.0 bits (97), Expect = 5e-04
Identities = 38/145 (26%), Positives = 58/145 (40%), Gaps = 16/145 (11%)
Query: 117 RRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSK 176
RR RSRS R + RS RS S PRR + D+ K R+R R +
Sbjct: 344 RRRRSRSGTRSPKKPRSPKRKLSRSPS---------PRRHKKEKKKDKDKERSRD-ERER 393
Query: 177 SNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSK 236
S S+ + +K+ + KS S TR + + G EKE ++++ P
Sbjct: 394 STSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEE------QGYDSEKEKKEEKKPIET 447
Query: 237 SQSRSQSRSRSKSRSRSWTSPKSSG 261
+++ S K S K +G
Sbjct: 448 GSPKTKECSVEKGTGDSLRESKVNG 472
Score = 37.0 bits (84), Expect = 0.017
Identities = 23/78 (29%), Positives = 35/78 (44%)
Query: 175 SKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPR 234
S S S + ++ MK ++S K + + H +S SR +
Sbjct: 207 SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRH 266
Query: 235 SKSQSRSQSRSRSKSRSR 252
+S+SRS+ RS SKSRSR
Sbjct: 267 RRSRSRSRRRSHSKSRSR 284
Score = 35.8 bits (81), Expect = 0.039
Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 1/79 (1%)
Query: 176 KSNSRSRSKSQPKKEMK-AKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPR 234
KS++ S+ + K ++ A+S +A + + S++ +S R S + R
Sbjct: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSR 270
Query: 235 SKSQSRSQSRSRSKSRSRS 253
S+S+ RS S+SRS+ RS+S
Sbjct: 271 SRSRRRSHSKSRSRRRSKS 289
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 71.2 bits (173), Expect = 8e-13
Identities = 67/180 (37%), Positives = 87/180 (48%), Gaps = 19/180 (10%)
Query: 84 QFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYR-RSY 142
Q + D +TP++ + R+ S + R+RS SY RSRSRS +YR RSY
Sbjct: 1294 QESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSY 1353
Query: 143 SPRNSR---PTGRPRRSRSHSDNDRFKHRNRSFSRSKSNS---RSRSKSQPKKEMKAKSR 196
S SR GR RSRS S HR S SRS+S+S SRS+S ++SR
Sbjct: 1354 SRSRSRGWYSRGR-TRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSR 1412
Query: 197 SRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQS-RSQSRSRSKSRSRSWT 255
SRS S ++DS Y G Y + SR S S+S RS S RS S S ++
Sbjct: 1413 SRSRS-------QRSDS---YHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESSRYS 1462
Score = 62.0 bits (149), Expect = 5e-10
Identities = 47/154 (30%), Positives = 65/154 (42%), Gaps = 3/154 (1%)
Query: 108 SRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKH 167
S+Y D RSRS R SRSRS+ +Y RS S +S R SRSHS N H
Sbjct: 679 SKYSDRSSESSPRSRS---RSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDH 735
Query: 168 RNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKES 227
S S S ++ S + K+ +++ + S SH K +S+ + Y G
Sbjct: 736 SQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCV 795
Query: 228 RKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSSG 261
RK RS S S S ++S + G
Sbjct: 796 RKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQG 829
Score = 60.8 bits (146), Expect = 1e-09
Identities = 52/177 (29%), Positives = 79/177 (44%), Gaps = 23/177 (12%)
Query: 107 SSRYDDYDRYRRSRSRSY-----ERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSD 161
SSR+D+ +RSRS SY + +R R+ ++ + + + R H
Sbjct: 394 SSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQ 453
Query: 162 NDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTD--------- 212
+ + S S +S R KS +E ++S S S+ H+ R SK+D
Sbjct: 454 TKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTH 513
Query: 213 -------SKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKS--RSRSWTSPKSS 260
SK+H +S SR SR S S+SRS+SRS SKS R R+ SP+ +
Sbjct: 514 SSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKT 570
Score = 60.8 bits (146), Expect = 1e-09
Identities = 54/166 (32%), Positives = 80/166 (48%), Gaps = 12/166 (7%)
Query: 95 QMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPR 154
+++ K V S +D+ R +R R R++ S D ++ S + + P
Sbjct: 1263 RIEIKSKNKVRPGSLFDEV----RKTARLNRRPRNQESSSD---EQTPSRDDDSQSRSPS 1315
Query: 155 RSRSHSDNDRFKHRNRSFSRSKSNSRSRSK-SQPKKEMKAKSRSR---SASHTKTRGTSK 210
RSRS S+ + +HR RS S S S SRSRS S + ++SRSR S T++R +S
Sbjct: 1316 RSRSKSET-KSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSY 1374
Query: 211 TDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTS 256
K+H S + S RS+S + SRS+SRSRS S
Sbjct: 1375 RSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRS 1420
Score = 52.0 bits (123), Expect = 5e-07
Identities = 47/166 (28%), Positives = 76/166 (45%), Gaps = 20/166 (12%)
Query: 107 SSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPR--------RSRS 158
SS R R SRSRSY R +RSRS ++ RS SP +SR R + RS S
Sbjct: 685 SSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSP-SSRSHSRNKYSDHSQCSRSSS 743
Query: 159 HS-----DNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKA---KSRSRSA---SHTKTRG 207
++ D R K R RS + S S + S +K + + K R RS+ ++++R
Sbjct: 744 YTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRS 803
Query: 208 TSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRS 253
+ S + S + K++ + + Q ++R + +S+S
Sbjct: 804 SLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKS 849
Score = 51.2 bits (121), Expect = 9e-07
Identities = 49/166 (29%), Positives = 72/166 (43%), Gaps = 15/166 (9%)
Query: 95 QMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPR 154
+MKAK + S Y + S SY +R S S Y + YS R+S + R
Sbjct: 635 EMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSK-YSDRSSESSPR-- 691
Query: 155 RSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSR-------SRSASHTKTRG 207
SRS S R R+ + SRS ++S SRS+S P ++++ SRS+S+T
Sbjct: 692 -SRSRSSRSRSYSRSYTRSRSLASSHSRSRS-PSSRSHSRNKYSDHSQCSRSSSYTSISS 749
Query: 208 TSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRS 253
+K +S + S KK S S ++ K R RS
Sbjct: 750 DDGRRAKRRLRSSGKKNSVSHKK---HSSSSEKTLHSKYVKGRDRS 792
Score = 49.3 bits (116), Expect = 3e-06
Identities = 47/201 (23%), Positives = 89/201 (44%), Gaps = 13/201 (6%)
Query: 47 TRRPRGFAYV-QFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPN---QMKAKEGR 102
++R R ++Y + D+ A + H+ R+ ++ +++ + +K + + K+ R
Sbjct: 403 SQRSRSWSYNGYYSDLSTARHSGHHKKRR----KEKKVKHKKKGKKQKHCRRHKQTKKRR 458
Query: 103 NVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDN 162
+ S RR +S R SRS S ++ S + + S D+
Sbjct: 459 ILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDS 518
Query: 163 DRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSR 222
R K ++S+SR S SR+ SKS ++KSRS S S G K SK+ K+ S+
Sbjct: 519 YRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKS-----GHRKRASKSPRKTASQ 573
Query: 223 YEKESRKKEPPRSKSQSRSQS 243
+ K P + +++++
Sbjct: 574 LSENKPVKTEPLRATMAQNEN 594
Score = 47.0 bits (110), Expect = 2e-05
Identities = 65/227 (28%), Positives = 93/227 (40%), Gaps = 62/227 (27%)
Query: 98 AKEGRNVYSSSRYDDYDRYR-RSRSRSYERRRSRSR----SFDYNYRRSYSPRNSRPTGR 152
+K ++V SS + D YR +S S+SY R SRSR S ++ RS S +S+ R
Sbjct: 501 SKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHR 560
Query: 153 PRRSRSH-------SDNDRFKH--------RNRS---------------FSRSKSNSRSR 182
R S+S S+N K +N + S S SR +
Sbjct: 561 KRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWK 620
Query: 183 SKSQPKK-------EMKAKSR-----------------SRSASHTKTRGTSKTDSKTHYK 218
+P K EMKAK+ S+S+ K S++D T+ K
Sbjct: 621 PGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSK 680
Query: 219 SGSRYEKES--RKKEPPRSKSQSRSQSRSRSKSRSRSWT-SPKSSGH 262
R + S + RS+S SRS +RSRS + S S + SP S H
Sbjct: 681 YSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSH 727
Score = 41.2 bits (95), Expect = 0.001
Identities = 39/123 (31%), Positives = 58/123 (47%), Gaps = 26/123 (21%)
Query: 141 SYSPRNSRPTGRP---RRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRS 197
+YS N + TG + +S++D+ + S S+S+ RSRS+S SRS
Sbjct: 649 TYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRS---------SRS 699
Query: 198 RSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSK-SRSRSWTS 256
RS S + TR S S + +S P S+S SR++ S+ SRS S+TS
Sbjct: 700 RSYSRSYTRSRSLASSHSRSRS-------------PSSRSHSRNKYSDHSQCSRSSSYTS 746
Query: 257 PKS 259
S
Sbjct: 747 ISS 749
Score = 35.0 bits (79), Expect = 0.066
Identities = 30/166 (18%), Positives = 62/166 (37%), Gaps = 9/166 (5%)
Query: 80 QIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYR 139
Q +Q Q ++ Q + + N +R ++ + + R + ++R+ + + R
Sbjct: 813 QSSVQATQSAQEKEKQGQMERTHNKQEKNRGEE--KSKSERECPHSKKRTLKENLSDHLR 870
Query: 140 RSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRS 199
P+ G S S+S+ D K+ S + S + E+ S
Sbjct: 871 NGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEV-------S 923
Query: 200 ASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRS 245
H K + T+K+ + T + K S+++ S S S +
Sbjct: 924 EIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSEN 969
Score = 32.7 bits (73), Expect = 0.33
Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 8/99 (8%)
Query: 152 RPRRSRSHSDNDRFKHRNRSFSRSKSNS--------RSRSKSQPKKEMKAKSRSRSASHT 203
+ R+ +HS+ + S S S S S R + K +PK + K R ++S
Sbjct: 187 KKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSE 246
Query: 204 KTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQ 242
+ R + K H + EK S R K R +
Sbjct: 247 EPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPE 285
Score = 32.7 bits (73), Expect = 0.33
Identities = 24/80 (30%), Positives = 43/80 (53%), Gaps = 9/80 (11%)
Query: 190 EMKAKSRSRSAS-HTKTRGTSKTDSKTHYKSGSRYEK--------ESRKKEPPRSKSQSR 240
E+K+K++ R S + R T++ + + + S E+ +SR RSKS+++
Sbjct: 1265 EIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETK 1324
Query: 241 SQSRSRSKSRSRSWTSPKSS 260
S+ R+RS S S S + +SS
Sbjct: 1325 SRHRTRSVSYSHSRSRSRSS 1344
Score = 30.4 bits (67), Expect = 1.6
Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 15/100 (15%)
Query: 161 DNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSG 220
+ R K + S S SNS S S+S + E++ + RSR H + + K
Sbjct: 186 EKKRKKPTHSEGSDSSSNSSSSSESSSESELEHE-RSRRRKHKR---------RPKVKRS 235
Query: 221 SRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSS 260
+ KE+ E PR+K + S RS T+ K S
Sbjct: 236 KKRRKEASSSEEPRNKHAMNPKGHS-----ERSDTNEKRS 270
Score = 28.5 bits (62), Expect = 6.2
Identities = 31/151 (20%), Positives = 57/151 (37%), Gaps = 11/151 (7%)
Query: 90 RKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSY--SPRNS 147
++ P ++K+ R SSS R++ + S D N +RS S +
Sbjct: 227 KRRPKVKRSKKRRKEASSSE--------EPRNKHAMNPKGHSERSDTNEKRSVDSSAKRE 278
Query: 148 RPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRG 207
+P RP +N R+ ++ + + + K S S+S K RG
Sbjct: 279 KPVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQKP-SVSKSGRKIKGRG 337
Query: 208 TSKTDSKTHYKSGSRYEKESRKKEPPRSKSQ 238
T + + +S S + + + PP K +
Sbjct: 338 TIRYHTPPRSRSCSESDDDDSSETPPHWKEE 368
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 70.1 bits (170), Expect = 2e-12
Identities = 47/134 (35%), Positives = 70/134 (52%), Gaps = 11/134 (8%)
Query: 115 RYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSR 174
R+ RSRS + + RRSRSRS Y+ R +R R RR + + +R + RNRS SR
Sbjct: 557 RHSRSRSPTIKARRSRSRS--YSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSR 614
Query: 175 SKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPR 234
+ SRSRS+ + R+ AS +++R K D + SG+ ++ + KE R
Sbjct: 615 ERRRSRSRSRDR---------RTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQER 665
Query: 235 SKSQSRSQSRSRSK 248
K +SRS + R K
Sbjct: 666 KKERSRSIDKDRKK 679
Score = 59.3 bits (142), Expect = 3e-09
Identities = 52/161 (32%), Positives = 72/161 (44%), Gaps = 19/161 (11%)
Query: 117 RRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHS----DNDR-------F 165
RRS S ER R R+RS RRS S R T R RSRS D+ R
Sbjct: 595 RRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSH 654
Query: 166 KHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEK 225
KH+ + + + RSRS K+ K K + R K + K + K +K S+ ++
Sbjct: 655 KHKGEAKEQERKKERSRSID---KDRKKKDKEREREQDKRKEKQKREEK-DFKFSSQDDR 710
Query: 226 ESRKKEPPRSKSQSRSQS----RSRSKSRSRSWTSPKSSGH 262
RK+E R+ S+S S S R S+ S+ T+ S H
Sbjct: 711 LKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKH 751
Score = 53.5 bits (127), Expect = 2e-07
Identities = 57/204 (27%), Positives = 85/204 (41%), Gaps = 52/204 (25%)
Query: 94 NQMKAKEGRNVYSSSRYDDYDRYRRSRSRS------------------------YERRRS 129
N+ ++E R S SR +R RSRSR ER++
Sbjct: 609 NRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKE 668
Query: 130 RSRSFDYNYRRSYSPRNSRPTGRPRRSRSH-------SDNDRFKHRN---RSFSRSKSNS 179
RSRS D + ++ R R + + S +DR K + R+FSRS S S
Sbjct: 669 RSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSIS 728
Query: 180 ----RSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRS 235
R S+ KK S+ S S + R +S++ GS EK+++K + RS
Sbjct: 729 VKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSES-------PGSSKEKKAKKPKHSRS 781
Query: 236 KSQSRSQ-------SRSRSKSRSR 252
+S +SQ + +SKSRSR
Sbjct: 782 RSVEKSQRSGKKASRKHKSKSRSR 805
Score = 51.6 bits (122), Expect = 7e-07
Identities = 52/177 (29%), Positives = 84/177 (47%), Gaps = 24/177 (13%)
Query: 81 IEIQFAQGD-----RKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFD 135
+E + A GD ++TPN+ + + + + ++ RSRS S S S S
Sbjct: 469 LEAREADGDVVNEKKRTPNETTSV----LEPKKEHKEKEKQGRSRSGS-----SSSGSSS 519
Query: 136 YNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKS 195
N R S ++ T S S + R R+ S R K +SRSRS + +KA+
Sbjct: 520 SNSRTS----STSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPT-----IKAR- 569
Query: 196 RSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSR 252
RSRS S+++ ++ + R + S ++E R++S SR + RSRS+SR R
Sbjct: 570 RSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDR 626
Score = 38.1 bits (87), Expect = 0.008
Identities = 35/151 (23%), Positives = 66/151 (43%), Gaps = 20/151 (13%)
Query: 112 DYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRS 171
+ + + S +R D + +P + P++ H + ++ + R+RS
Sbjct: 454 EMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKE--HKEKEK-QGRSRS 510
Query: 172 FSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKE 231
S S +S S S++ S S+S++ + G+S+T S++ S R ++ SR +
Sbjct: 511 GSSSSGSSSSNSRTS-----STSSTVSSSSYSSSSGSSRTSSRS--SSPKRKKRHSRSRS 563
Query: 232 PPRSKSQSRSQS----------RSRSKSRSR 252
P +SRS+S R+R K R R
Sbjct: 564 PTIKARRSRSRSYSRRIKIESNRARVKIRDR 594
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 70.1 bits (170), Expect = 2e-12
Identities = 74/214 (34%), Positives = 88/214 (41%), Gaps = 49/214 (22%)
Query: 94 NQMKAKEGRN-VYSSSRYDDYDRYRRSRSRSYER----RRSRSRSFDYNYRRSYSPRNSR 148
N+ K R+ S SR RR RS+S R RSRSR D RRS SP R
Sbjct: 301 NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKD--RRRSKSPHKKR 358
Query: 149 PTGRPR---RSRSHS------------------DNDRFKHRNRSFSRSKSNSR------- 180
R R RSRSHS + DR K R R R K R
Sbjct: 359 SKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRD 418
Query: 181 -SRSKSQPKKEMKAKSRSRSASHTKTRGTSK----TDSKTHYKSGSRYEKESRKKE---- 231
R K + K + K + R R H K R K K K S+ E RKK+
Sbjct: 419 KEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSR 478
Query: 232 -PPRS---KSQSRSQSRSRSKSRSRSWT-SPKSS 260
PPRS +SRS SR R + RSRS + SP++S
Sbjct: 479 TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTS 512
Score = 66.2 bits (160), Expect = 3e-11
Identities = 67/259 (25%), Positives = 116/259 (44%), Gaps = 39/259 (15%)
Query: 11 SLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHN 70
+++V N+ T + D EF + V +V + +P FA+V+F D AL
Sbjct: 183 TVYVGNLNSQTTTADQLLEFFKQVGEVK-FVRMAGDETQPTRFAFVEFADQNSVPRALA- 240
Query: 71 LDRKWICGRQIEIQFAQGDRKTPNQM--------------KAKEGRNVYSSSRYDDYDRY 116
+ R ++I + P +M + +E ++ S++ + +
Sbjct: 241 FNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKS 300
Query: 117 R-RSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRS 175
R RS RS+SRS +S+ R +RS+S KHR+RS +RS
Sbjct: 301 NERKGGRSRSHTRSKSRS------------SSKSHSRRKRSQS-------KHRSRSHNRS 341
Query: 176 KS--NSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPP 233
+S R RSKS KK K++ R +S S + +R K D++ K R +++ R+KE
Sbjct: 342 RSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRK-DTREKIKEKERVKEKDREKERE 400
Query: 234 RSKSQSRSQSRSRSKSRSR 252
R K + + + R ++K R +
Sbjct: 401 REKEREKEKERGKNKDRDK 419
Score = 54.3 bits (129), Expect = 1e-07
Identities = 44/187 (23%), Positives = 76/187 (40%), Gaps = 18/187 (9%)
Query: 89 DRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSR 148
D++ + K KE V R + +R + R E+ R +++ D + +
Sbjct: 375 DKRKDTREKIKEKERVKEKDREKERER---EKEREKEKERGKNKDRDKEREKDREKDKEK 431
Query: 149 PTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMK----------AKSRSR 198
R R D D+ K + + + + RS+ + +K+ K A RSR
Sbjct: 432 DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSR 491
Query: 199 SASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEP--PRSKSQSRSQSR---SRSKSRSRS 253
S+S + R S++ S++ S + K SR P K + R + R S + R RS
Sbjct: 492 SSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 551
Query: 254 WTSPKSS 260
+ KSS
Sbjct: 552 TSMRKSS 558
Score = 50.1 bits (118), Expect = 2e-06
Identities = 41/159 (25%), Positives = 65/159 (40%), Gaps = 10/159 (6%)
Query: 89 DRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSR 148
DR+ + + ++ R+ D + RS+ + +R + + R + R SR
Sbjct: 432 DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSR 491
Query: 149 PTGRPRRSRSHSDNDRFKHRNRSFSRSKSNS---RSRSKSQPKKE------MKAKSRSRS 199
+ R RR R + R +++ R S S RSR+K K+E + + R RS
Sbjct: 492 SSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 551
Query: 200 ASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQ 238
S K+ K S S EKE KEP S S+
Sbjct: 552 TSMRKSSNDRDGKEKLEKNSTSLKEKE-HNKEPDSSVSK 589
Score = 49.3 bits (116), Expect = 3e-06
Identities = 42/162 (25%), Positives = 65/162 (40%), Gaps = 9/162 (5%)
Query: 97 KAKEGRNVYSSSRYDDYDRYR-RSRSRSYERRRSRSRSFDYNYRRSYSPRN-SRPTGRPR 154
K K+ D D+ + + + + ER + RS+ D ++ R R R
Sbjct: 429 KEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR 488
Query: 155 RSRSHSDNDRFKHRNRSFSRSKSNSR------SRSKSQPKKEMKAKSRSRSASHTKTRGT 208
RSRS S +R + R+RS SRS S+ SRS S + K K R + H R
Sbjct: 489 RSRS-SSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRE 547
Query: 209 SKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSR 250
+ + S R KE +K K + ++ S S+
Sbjct: 548 RERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSK 589
Score = 43.5 bits (101), Expect = 2e-04
Identities = 47/174 (27%), Positives = 67/174 (38%), Gaps = 24/174 (13%)
Query: 79 RQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYR---------------RSRSRS 123
R+ E + + K + + KE S+ D R + RSRS S
Sbjct: 435 REREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSS 494
Query: 124 YERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNR-SFSRSKSNSRSR 182
ERRR RSRS + R S + + RSR+ D R K R+ S R + S S
Sbjct: 495 RERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSM 554
Query: 183 SKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSK 236
KS ++ K K S S + + DS KE K+ PR++
Sbjct: 555 RKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSV--------SKEVDDKDAPRTE 600
Score = 29.6 bits (65), Expect = 2.8
Identities = 15/29 (51%), Positives = 18/29 (62%)
Query: 231 EPPRSKSQSRSQSRSRSKSRSRSWTSPKS 259
EP KS R RSRS +RS+S +S KS
Sbjct: 294 EPESGKSNERKGGRSRSHTRSKSRSSSKS 322
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 70.1 bits (170), Expect = 2e-12
Identities = 74/214 (34%), Positives = 88/214 (41%), Gaps = 49/214 (22%)
Query: 94 NQMKAKEGRN-VYSSSRYDDYDRYRRSRSRSYER----RRSRSRSFDYNYRRSYSPRNSR 148
N+ K R+ S SR RR RS+S R RSRSR D RRS SP R
Sbjct: 185 NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKD--RRRSKSPHKKR 242
Query: 149 PTGRPR---RSRSHS------------------DNDRFKHRNRSFSRSKSNSR------- 180
R R RSRSHS + DR K R R R K R
Sbjct: 243 SKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRD 302
Query: 181 -SRSKSQPKKEMKAKSRSRSASHTKTRGTSK----TDSKTHYKSGSRYEKESRKKE---- 231
R K + K + K + R R H K R K K K S+ E RKK+
Sbjct: 303 KEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSR 362
Query: 232 -PPRS---KSQSRSQSRSRSKSRSRSWT-SPKSS 260
PPRS +SRS SR R + RSRS + SP++S
Sbjct: 363 TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTS 396
Score = 66.2 bits (160), Expect = 3e-11
Identities = 67/259 (25%), Positives = 116/259 (44%), Gaps = 39/259 (15%)
Query: 11 SLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHN 70
+++V N+ T + D EF + V +V + +P FA+V+F D AL
Sbjct: 67 TVYVGNLNSQTTTADQLLEFFKQVGEVK-FVRMAGDETQPTRFAFVEFADQNSVPRALA- 124
Query: 71 LDRKWICGRQIEIQFAQGDRKTPNQM--------------KAKEGRNVYSSSRYDDYDRY 116
+ R ++I + P +M + +E ++ S++ + +
Sbjct: 125 FNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKS 184
Query: 117 R-RSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRS 175
R RS RS+SRS +S+ R +RS+S KHR+RS +RS
Sbjct: 185 NERKGGRSRSHTRSKSRS------------SSKSHSRRKRSQS-------KHRSRSHNRS 225
Query: 176 KS--NSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPP 233
+S R RSKS KK K++ R +S S + +R K D++ K R +++ R+KE
Sbjct: 226 RSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRK-DTREKIKEKERVKEKDREKERE 284
Query: 234 RSKSQSRSQSRSRSKSRSR 252
R K + + + R ++K R +
Sbjct: 285 REKEREKEKERGKNKDRDK 303
Score = 54.3 bits (129), Expect = 1e-07
Identities = 44/187 (23%), Positives = 76/187 (40%), Gaps = 18/187 (9%)
Query: 89 DRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSR 148
D++ + K KE V R + +R + R E+ R +++ D + +
Sbjct: 259 DKRKDTREKIKEKERVKEKDREKERER---EKEREKEKERGKNKDRDKEREKDREKDKEK 315
Query: 149 PTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMK----------AKSRSR 198
R R D D+ K + + + + RS+ + +K+ K A RSR
Sbjct: 316 DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSR 375
Query: 199 SASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEP--PRSKSQSRSQSR---SRSKSRSRS 253
S+S + R S++ S++ S + K SR P K + R + R S + R RS
Sbjct: 376 SSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 435
Query: 254 WTSPKSS 260
+ KSS
Sbjct: 436 TSMRKSS 442
Score = 50.1 bits (118), Expect = 2e-06
Identities = 41/159 (25%), Positives = 65/159 (40%), Gaps = 10/159 (6%)
Query: 89 DRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSR 148
DR+ + + ++ R+ D + RS+ + +R + + R + R SR
Sbjct: 316 DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSR 375
Query: 149 PTGRPRRSRSHSDNDRFKHRNRSFSRSKSNS---RSRSKSQPKKE------MKAKSRSRS 199
+ R RR R + R +++ R S S RSR+K K+E + + R RS
Sbjct: 376 SSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 435
Query: 200 ASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQ 238
S K+ K S S EKE KEP S S+
Sbjct: 436 TSMRKSSNDRDGKEKLEKNSTSLKEKE-HNKEPDSSVSK 473
Score = 49.3 bits (116), Expect = 3e-06
Identities = 42/162 (25%), Positives = 65/162 (40%), Gaps = 9/162 (5%)
Query: 97 KAKEGRNVYSSSRYDDYDRYR-RSRSRSYERRRSRSRSFDYNYRRSYSPRN-SRPTGRPR 154
K K+ D D+ + + + + ER + RS+ D ++ R R R
Sbjct: 313 KEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR 372
Query: 155 RSRSHSDNDRFKHRNRSFSRSKSNSR------SRSKSQPKKEMKAKSRSRSASHTKTRGT 208
RSRS S +R + R+RS SRS S+ SRS S + K K R + H R
Sbjct: 373 RSRS-SSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRE 431
Query: 209 SKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSR 250
+ + S R KE +K K + ++ S S+
Sbjct: 432 RERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSK 473
Score = 43.5 bits (101), Expect = 2e-04
Identities = 47/174 (27%), Positives = 67/174 (38%), Gaps = 24/174 (13%)
Query: 79 RQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYR---------------RSRSRS 123
R+ E + + K + + KE S+ D R + RSRS S
Sbjct: 319 REREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSS 378
Query: 124 YERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNR-SFSRSKSNSRSR 182
ERRR RSRS + R S + + RSR+ D R K R+ S R + S S
Sbjct: 379 RERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSM 438
Query: 183 SKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSK 236
KS ++ K K S S + + DS KE K+ PR++
Sbjct: 439 RKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSV--------SKEVDDKDAPRTE 484
Score = 29.6 bits (65), Expect = 2.8
Identities = 15/29 (51%), Positives = 18/29 (62%)
Query: 231 EPPRSKSQSRSQSRSRSKSRSRSWTSPKS 259
EP KS R RSRS +RS+S +S KS
Sbjct: 178 EPESGKSNERKGGRSRSHTRSKSRSSSKS 206
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.126 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,007,219
Number of Sequences: 37866
Number of extensions: 433390
Number of successful extensions: 11551
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 485
Number of HSP's successfully gapped in prelim test: 380
Number of HSP's that attempted gapping in prelim test: 2679
Number of HSP's gapped (non-prelim): 3662
length of query: 262
length of database: 18,247,518
effective HSP length: 100
effective length of query: 162
effective length of database: 14,460,918
effective search space: 2342668716
effective search space used: 2342668716
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.