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Search of human proteins with 110611156
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
(1575 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 3320 0.0
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 1384 0.0
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 597 e-170
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 590 e-168
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 590 e-168
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 565 e-160
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 565 e-160
gi|21264602 laminin alpha 5 [Homo sapiens] 475 e-133
gi|148613884 netrin 1 [Homo sapiens] 384 e-106
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 307 6e-83
gi|5453810 netrin 3 [Homo sapiens] 306 1e-82
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 305 2e-82
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 295 3e-79
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 295 3e-79
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 282 2e-75
gi|143770880 laminin, beta 4 [Homo sapiens] 277 7e-74
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 253 8e-67
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 253 8e-67
gi|189083719 laminin, beta 3 precursor [Homo sapiens] 253 8e-67
gi|93204871 netrin 4 [Homo sapiens] 234 4e-61
gi|219842266 usherin isoform B [Homo sapiens] 231 3e-60
gi|219842259 usherin isoform A [Homo sapiens] 231 3e-60
gi|164414431 netrin G1 isoform 1 [Homo sapiens] 212 2e-54
gi|190014607 netrin G2 [Homo sapiens] 197 9e-50
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 164 5e-40
gi|24308065 netrin 5 [Homo sapiens] 164 6e-40
gi|54312078 netrin G1 isoform 3 [Homo sapiens] 152 2e-36
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 146 1e-34
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 145 2e-34
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 145 2e-34
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 3320 bits (8609), Expect = 0.0
Identities = 1575/1575 (100%), Positives = 1575/1575 (100%)
Query: 1 MAAAALLLGLALLAPRAAGAGMGACYDGAGRPQRCLPVFENAAFGRLAQASHTCGSPPED 60
MAAAALLLGLALLAPRAAGAGMGACYDGAGRPQRCLPVFENAAFGRLAQASHTCGSPPED
Sbjct: 1 MAAAALLLGLALLAPRAAGAGMGACYDGAGRPQRCLPVFENAAFGRLAQASHTCGSPPED 60
Query: 61 FCPHVGAAGAGAHCQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNI 120
FCPHVGAAGAGAHCQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNI
Sbjct: 61 FCPHVGAAGAGAHCQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNI 120
Query: 121 TLRLGKAYEITYVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLR 180
TLRLGKAYEITYVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLR
Sbjct: 121 TLRLGKAYEITYVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLR 180
Query: 181 PGEDERVAFCTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDR 240
PGEDERVAFCTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDR
Sbjct: 181 PGEDERVAFCTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDR 240
Query: 241 LNTFGDDIFKDPKVLQSYYYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTD 300
LNTFGDDIFKDPKVLQSYYYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTD
Sbjct: 241 LNTFGDDIFKDPKVLQSYYYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTD 300
Query: 301 CERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTA 360
CERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTA
Sbjct: 301 CERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTA 360
Query: 361 GPHCERCQENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFH 420
GPHCERCQENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFH
Sbjct: 361 GPHCERCQENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFH 420
Query: 421 SLSEGGCRPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSC 480
SLSEGGCRPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSC
Sbjct: 421 SLSEGGCRPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSC 480
Query: 481 FCYGHSKVCASTAQFQVHHILSDFHQGAEGWWARSVGGSEHPPQWSPNGVLLSPEDEEEL 540
FCYGHSKVCASTAQFQVHHILSDFHQGAEGWWARSVGGSEHPPQWSPNGVLLSPEDEEEL
Sbjct: 481 FCYGHSKVCASTAQFQVHHILSDFHQGAEGWWARSVGGSEHPPQWSPNGVLLSPEDEEEL 540
Query: 541 TAPEKFLGDQRFSYGQPLILTFRVPPGDSPLPVQLRLEGTGLALSLRHSSLSGPQDAGHP 600
TAPEKFLGDQRFSYGQPLILTFRVPPGDSPLPVQLRLEGTGLALSLRHSSLSGPQDAGHP
Sbjct: 541 TAPEKFLGDQRFSYGQPLILTFRVPPGDSPLPVQLRLEGTGLALSLRHSSLSGPQDAGHP 600
Query: 601 REVELRFHLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSPGPSPAGPVFLTEVRLTSAR 660
REVELRFHLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSPGPSPAGPVFLTEVRLTSAR
Sbjct: 601 REVELRFHLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSPGPSPAGPVFLTEVRLTSAR 660
Query: 661 PGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTG 720
PGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTG
Sbjct: 661 PGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTG 720
Query: 721 ICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPG 780
ICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPG
Sbjct: 721 ICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPG 780
Query: 781 QRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTG 840
QRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTG
Sbjct: 781 QRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTG 840
Query: 841 DHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSR 900
DHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSR
Sbjct: 841 DHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSR 900
Query: 901 CYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIK 960
CYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIK
Sbjct: 901 CYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIK 960
Query: 961 GCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCYALV 1020
GCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCYALV
Sbjct: 961 GCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCYALV 1020
Query: 1021 KEEAAKLKARLTLTEGWLQGSDCGSPWGPLDILLGEAPRGDVYQGHHLLPGAREAFLEQM 1080
KEEAAKLKARLTLTEGWLQGSDCGSPWGPLDILLGEAPRGDVYQGHHLLPGAREAFLEQM
Sbjct: 1021 KEEAAKLKARLTLTEGWLQGSDCGSPWGPLDILLGEAPRGDVYQGHHLLPGAREAFLEQM 1080
Query: 1081 MSLEGAVKAAREQLQRLNKGARCAQAGSQKTCTQLADLEAVLESSEEEILHAAAILASLE 1140
MSLEGAVKAAREQLQRLNKGARCAQAGSQKTCTQLADLEAVLESSEEEILHAAAILASLE
Sbjct: 1081 MSLEGAVKAAREQLQRLNKGARCAQAGSQKTCTQLADLEAVLESSEEEILHAAAILASLE 1140
Query: 1141 IPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRALLASNTSYALLWNLLEGRVA 1200
IPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRALLASNTSYALLWNLLEGRVA
Sbjct: 1141 IPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRALLASNTSYALLWNLLEGRVA 1200
Query: 1201 LETQRDLEDRYQEVQAAQKALRTAVAEVLPEAESVLATVQQVGADTAPYLALLASPGALP 1260
LETQRDLEDRYQEVQAAQKALRTAVAEVLPEAESVLATVQQVGADTAPYLALLASPGALP
Sbjct: 1201 LETQRDLEDRYQEVQAAQKALRTAVAEVLPEAESVLATVQQVGADTAPYLALLASPGALP 1260
Query: 1261 QKSRAEDLGLKAKALEKTVASWQHMATEAARTLQTAAQATLRQTEPLTKLHQEARAALTQ 1320
QKSRAEDLGLKAKALEKTVASWQHMATEAARTLQTAAQATLRQTEPLTKLHQEARAALTQ
Sbjct: 1261 QKSRAEDLGLKAKALEKTVASWQHMATEAARTLQTAAQATLRQTEPLTKLHQEARAALTQ 1320
Query: 1321 ASSSVQAATVTVMGARTLLADLEGMKLQFPRPKDQAALQRKADSVSDRLLADTRKKTKQA 1380
ASSSVQAATVTVMGARTLLADLEGMKLQFPRPKDQAALQRKADSVSDRLLADTRKKTKQA
Sbjct: 1321 ASSSVQAATVTVMGARTLLADLEGMKLQFPRPKDQAALQRKADSVSDRLLADTRKKTKQA 1380
Query: 1381 ERMLGNAAPLSSSAKKKGREAEVLAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQA 1440
ERMLGNAAPLSSSAKKKGREAEVLAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQA
Sbjct: 1381 ERMLGNAAPLSSSAKKKGREAEVLAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQA 1440
Query: 1441 SQQVLASEARRQELEEAERVGAGLSEMEQQIRESRISLEKDIETLSELLARLGSLDTHQA 1500
SQQVLASEARRQELEEAERVGAGLSEMEQQIRESRISLEKDIETLSELLARLGSLDTHQA
Sbjct: 1441 SQQVLASEARRQELEEAERVGAGLSEMEQQIRESRISLEKDIETLSELLARLGSLDTHQA 1500
Query: 1501 PAQALNETQWALERLRLQLGSPGSLQRKLSLLEQESQQQELQIQGFESDLAEIRADKQNL 1560
PAQALNETQWALERLRLQLGSPGSLQRKLSLLEQESQQQELQIQGFESDLAEIRADKQNL
Sbjct: 1501 PAQALNETQWALERLRLQLGSPGSLQRKLSLLEQESQQQELQIQGFESDLAEIRADKQNL 1560
Query: 1561 EAILHSLPENCASWQ 1575
EAILHSLPENCASWQ
Sbjct: 1561 EAILHSLPENCASWQ 1575
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 1384 bits (3583), Expect = 0.0
Identities = 699/1595 (43%), Positives = 971/1595 (60%), Gaps = 48/1595 (3%)
Query: 10 LALLAPRAAG----AGMGACYDGAGRPQRCLPVFENAAFGRLAQASHTCGSPPEDFCPHV 65
LA+LA AA A M C D GRPQRC+P F NAAF A++TCG+PPE++C
Sbjct: 21 LAVLAAAAAAGCAQAAMDECTDEGGRPQRCMPEFVNAAFNVTVVATNTCGTPPEEYCVQT 80
Query: 66 GAAGAGAHCQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLG 125
G G C CDA P H A++LTD+++Q ++TWWQS +M GVQYP+S+N+TL LG
Sbjct: 81 GVTGVTKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPSSINLTLHLG 140
Query: 126 KAYEITYVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPGEDE 185
KA++ITYVRLKFHTSRPESFAIYKR+R DGPW PYQ+YS SC+ TY + ++R G DE
Sbjct: 141 KAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDE 200
Query: 186 RVAFCTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLNTFG 245
+ A CT EFSDISPL+GGNVAFSTLEGRPSAYNF+ SP LQEWVT+T++ ++L+RLNTFG
Sbjct: 201 QQALCTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFG 260
Query: 246 DDIFKDPKVLQSYYYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCL 305
D++F DPKVL+SYYYA+SDF+VGGRCKCNGHASEC + +L C C+HNT G DCE+CL
Sbjct: 261 DEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCL 320
Query: 306 PFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCE 365
PFF DRPW R TAE+A ECLPC+C+GRS+EC FD EL+RSTGHGG C +C+D+T G HCE
Sbjct: 321 PFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCE 380
Query: 366 RCQENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEG 425
RC+ENF+ C C C GSL QCD G C+CKP V G KCDRC PGFHSL+E
Sbjct: 381 RCRENFFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEA 440
Query: 426 GCRPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGH 485
GCRPC+C+P+GS+D C+ +GRC CK+NVEG C+RC+PG FNL+ NP GC+ CFC+GH
Sbjct: 441 GCRPCSCDPSGSIDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGH 500
Query: 486 SKVCASTAQFQVHHILSDFHQGAEGWWARSVGGSEHPPQWSPN----GVLLSPEDEEELT 541
S VC + + V+ I S F +GW A GSE +WS V+
Sbjct: 501 SSVCTNAVGYSVYSISSTFQIDEDGWRAEQRDGSEASLEWSSERQDIAVISDSYFPRYFI 560
Query: 542 APEKFLGDQRFSYGQPLILTFRVPPGDSPLPVQ-LRLEGTGLALSLRHSSLSGPQDAGHP 600
AP KFLG Q SYGQ L +FRV D+ L + L LEG GL +S+ + Q +P
Sbjct: 561 APAKFLGKQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVSVPLIA----QGNSYP 616
Query: 601 REVELR--FHLQE-TSEDVAPPLPPFHFQRLLANLTSLRLRVSPGPSPAGPVFLTEVRLT 657
E ++ F L E T P L PF FQ+LL NLTS+++R + AG +L +V L
Sbjct: 617 SETTVKYVFRLHEATDYPWRPALTPFEFQKLLNNLTSIKIRGTYSERSAG--YLDDVTLA 674
Query: 658 SARPGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHG-TCD 716
SARPG PA+WVE C+CP GY GQFCE C GY+RE P GPY+ CV C CN H TCD
Sbjct: 675 SARPGPGVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCD 734
Query: 717 PNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTH 776
P TG+C C +T GP CE+C G+YG+ AG + DCQPCPCPG S+C +P+++EVVCT+
Sbjct: 735 PETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTN 794
Query: 777 CPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLH 836
CP G G+RCE+CDDG+FGDPLG G + C CQCS N+DPNAVGNC+ L+G CL+C++
Sbjct: 795 CPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIY 854
Query: 837 NTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTAR 896
NT G +C+ C++GF+G+ LAP PADKC C+C+ G++ +Q C+PVTGQC CLPHVT +
Sbjct: 855 NTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQ 914
Query: 897 DCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFG 956
DC C PGF++LQ G+GC C CH LGS QC +TGQC C+PG+TGQ C+RC++ FG
Sbjct: 915 DCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFG 974
Query: 957 FSIKGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSC 1016
F +GC+ C C P G+ S QC ++G C CR GF G +CD+C +N+F CQ+CP+C
Sbjct: 975 FGPEGCKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPAC 1034
Query: 1017 YALVKEEAAKLKARLTLTEGWLQGSDCGSPW---GPLDILLGEAPRG--DVYQGHHLLPG 1071
Y LVK++ A + +L E + G + L EA R D+ + +
Sbjct: 1035 YRLVKDKVADHRVKLQELESLIANLGTGDEMVTDQAFEDRLKEAEREVMDLLREAQDVKD 1094
Query: 1072 AREAFLEQMMSLEGAVKAAREQLQRLNKGARCAQAGSQKTCTQLADLEAVLESSEEEILH 1131
+ ++++ + + + +LQ + +++ + + E ++E + E+
Sbjct: 1095 VDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAEQARAHVENTERLIEIASRELEK 1154
Query: 1132 AAAILASLEIPQ-EGPSQPTKWSHLATEARALARSHRDTATKIAATAWRALLASNTSYAL 1190
A A++ + Q E P + LA EAR LA H+ A I A A S +Y L
Sbjct: 1155 AKVAAANVSVTQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNL 1214
Query: 1191 LWNLL--EGRVALETQRDLEDRYQEVQAAQKALRTAVAEVLPEAESVLATVQQVGADTAP 1248
L L E + A E + +L +Y++ + + L A V EA+ ++ A
Sbjct: 1215 LLRTLAGENQTAFEIE-ELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYAS--- 1270
Query: 1249 YLALLASPGALPQKSRAEDLGLKAKALEKTV----ASWQHMATE-AARTLQTAAQATLRQ 1303
+A L+ + ++ A ++ ++A+ LE+ + ++ + + + L+ +
Sbjct: 1271 -VAQLSPLDSETLENEANNIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGK 1329
Query: 1304 TEPLT--KLHQEARAALTQASSSVQAATVTVMGARTLLADLEGMKLQFPRPKDQAALQRK 1361
TE T +L A AA A + + T+ A +L +L+ + K A +
Sbjct: 1330 TEQQTADQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALR 1389
Query: 1362 ADSVSDRLLADTRKKTKQAERMLGNAAPLSSSAKKKGREAEVLAKDSAKLAKALLRERKQ 1421
++ + + +KT++A++ LG+AA ++ AK K EAE +A K A + E ++
Sbjct: 1390 KIPAINQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAER 1449
Query: 1422 AHRRASRLTSQTQATLQQASQQVLASEARRQELEEAERVGAGLS-----EMEQQIRESRI 1476
+ L ++ L+Q Q+ R+Q+ + + + AG++ E E R+++
Sbjct: 1450 TFAEVTDLDNEVNNMLKQL-QEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKN 1508
Query: 1477 SLEKDIETLSELLARLGSLDTHQAPAQALNETQWALERLRLQLGSPGSLQRKLSLLEQES 1536
S+ + +++LL +LG LDT LNE + L + + ++ L RK+S LE E+
Sbjct: 1509 SVTSLLSIINDLLEQLGQLDT--VDLNKLNEIEGTLNKAKDEM-KVSDLDRKVSDLENEA 1565
Query: 1537 QQQELQIQGFESDLAEIRADKQNLEAILHSLPENC 1571
++QE I + D+ EI D +NLE I +LP C
Sbjct: 1566 KKQEAAIMDYNRDIEEIMKDIRNLEDIRKTLPSGC 1600
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 597 bits (1538), Expect = e-170
Identities = 378/1071 (35%), Positives = 509/1071 (47%), Gaps = 120/1071 (11%)
Query: 25 CYDGAGRPQRCLPVFENAAFGRLAQASHTCGSP-PEDFCPHV----GAAGAGAHCQRCD- 78
C R + P N A + TCG PE FC V G C+ CD
Sbjct: 12 CVAAQCRQRGLFPAILNLASNAHISTNATCGEKGPEMFCKLVEHVPGRPVRNPQCRICDG 71
Query: 79 -AADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKF 137
+A+P+ H S+ D + WWQSPS+ G +Y V ITL L + +++ YV +K
Sbjct: 72 NSANPRERHPISHAID----GTNNWWQSPSIQNGREYHW-VTITLDLRQVFQVAYVIIKA 126
Query: 138 HTSRPESFAIYKRSRADGPWEPYQFYSASCQKTYGR-----PEGQYLRPGEDERVAFCTS 192
+ I +RS + P+Q+Y+ S + R G +DE + CTS
Sbjct: 127 ANAPRPGNWILERSLDGTTFSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEVI--CTS 184
Query: 193 EFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIFK-- 250
+S + PL G + S + GRPSA + SP L E+ ++ + + L R+ T D+
Sbjct: 185 YYSRLVPLEHGEIHTSLINGRPSADDL--SPKLLEFTSARYIRLRLQRIRTLNADLMTLS 242
Query: 251 -------DPKVLQSYYYAVSDFSVGGRCKCNGHASECGPD-VAGQLACRCQHNTTGTDCE 302
DP V + YYY++ D SVGG C C GHAS C D +L C+C+HNT G C
Sbjct: 243 HREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCN 302
Query: 303 RCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGH---------GGRCH 353
RC P + +PW GT + + C CNC ++++C +D + + GG C
Sbjct: 303 RCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCI 362
Query: 354 HCRDHTAGPHCERCQENFYHWDPRM-------PCQPCDCQSAGSLHLQC--DDT------ 398
+C +T G +CE C + +Y P PC+PC+C GSL C DD
Sbjct: 363 NCLQNTMGINCETCIDGYYR--PHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHN 420
Query: 399 ----GTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSGRCPCKENV 454
G C CK TG KCDRC G+ C C CNP GS +P +G C CKENV
Sbjct: 421 GKQPGQCPCKEGYTGEKCDRCQLGYKDYPT--CVSCGCNPVGSASD-EPCTGPCVCKENV 477
Query: 455 EGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVCASTA--QFQVHH----ILSDFHQGA 508
EG CDRC+PG +NL+ NP GCS CFC+G S VC+S + QV+ +++D
Sbjct: 478 EGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPVGQVNSMSGWLVTDLISPR 537
Query: 509 EGWWARSVGGSEHPPQWSPNGVLLSPEDEEELTAPEKFLGDQRFSYGQPLILT----FRV 564
+ + G H + V+ + APE +LG++ ++G L T V
Sbjct: 538 KIPSQQDALGGRHQVSINNTAVMQRLAPKYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPV 597
Query: 565 PPGDSPL--PVQLRLEGTGLALSLRHSSLSGPQDAGHPREVELRFHLQETSEDVAPPLPP 622
DS L + ++G GL LS + LS + V L + E +D
Sbjct: 598 ETVDSNLMSHADVIIKGNGLTLSTQAEGLSLQPYEEYLNVVRL---VPENFQD------- 647
Query: 623 FHFQR---------LLANLTSLRLRVSPGPSPAGPVFLTEVRLTSARPGLSP--PASWVE 671
FH +R +LAN+T L +R + + L V L A A+ VE
Sbjct: 648 FHSKRQIDRDQLMTVLANVTHLLIRANYNSAKMALYRLESVSLDIASSNAIDLVVAADVE 707
Query: 672 ICSCPTGYTGQFCESCAPGYKR--EMPQGGPYASCVPCTCNQHGTCDPNTGICV-CSHHT 728
C CP GYTG CESC GY R + GG C PC C+ H G+C+ C+H+T
Sbjct: 708 HCECPQGYTGTSCESCLSGYYRVDGILFGG---ICQPCECHGHAAECNVHGVCIACAHNT 764
Query: 729 EGPSCERCLPGFYGNPFAGQADDCQPCPCP------GQSACTTIPESREVVCTHCPPGQR 782
G CE+CLPGFYG P G DCQPC CP S + + EVVC C PG
Sbjct: 765 TGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYS 824
Query: 783 GRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDH 842
G CE C DG++G+P + C C CSGNVDP+ G+CD ++G CL+CL NT G H
Sbjct: 825 GAWCERCADGYYGNPT---VPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAH 881
Query: 843 CEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCY 902
CE C +GFYG A+ A C C CH +GS S C TG C C P+VT + C +C
Sbjct: 882 CERCADGFYGDAVT---AKNCRACECHVKGSHS--AVCHLETGLCDCKPNVTGQQCDQCL 936
Query: 903 PGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGC 962
G++ L G GCR C C GS D C + GQC C PGV G+ CDRC GF+ + C
Sbjct: 937 HGYYGLDSGHGCRPCNCSVAGSVSDGCTDE-GQCHCVPGVAGKRCDRCAHGFYAYQDGSC 995
Query: 963 RACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQC 1013
C C + E G CVC P +G KC+ C D + CQ C
Sbjct: 996 TPCDCP--HTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQAC 1044
Score = 270 bits (690), Expect = 8e-72
Identities = 195/665 (29%), Positives = 287/665 (43%), Gaps = 111/665 (16%)
Query: 271 CKCN---GHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPC 327
C+C+ H++ C + C C+ N TG C++CL + ++ H C PC
Sbjct: 902 CECHVKGSHSAVCHLETG---LCDCKPNVTGQQCDQCLHGYYG-------LDSGHGCRPC 951
Query: 328 NCS---GRSEECTFDRELFRSTGHGG----RCHH-------------------------- 354
NCS S+ CT + + G G RC H
Sbjct: 952 NCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPET 1011
Query: 355 ----CRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGSLHLQCDD-TGTCACKPTVTG 409
C HT G CE C++ + +D + CQ C+C GS H +CD TG C CK G
Sbjct: 1012 GECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGG 1071
Query: 410 WKCDRCLPGFHSLSEGGCRPCTCNPAGS----------LDTCDPRSGRCPCKENVEGNLC 459
CD+C G+ + C PC C+ G+ L C +G CPCKENV G C
Sbjct: 1072 RACDQCSLGYRDFPD--CVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQC 1129
Query: 460 DRCRPGTFNLQPHNPAGCSSCFCYGHSKVCASTAQFQVHHILSDFHQGAEGWWARSV--- 516
+ CR GTF L+ NP GCS CFC G S +C+ + + + G++ R V
Sbjct: 1130 NECREGTFALRADNPLGCSPCFCSGLSHLCSELEDY----VRTPVTLGSDQPLLRVVSQS 1185
Query: 517 ---GGSEHPPQWSPNGVLLSPEDEEELTA-------PEKFLGDQRFSYGQPLILTFRV-- 564
G +E +P+ +L + + + A P++F GDQ +YG L +
Sbjct: 1186 NLRGTTEGVYYQAPDFLLDAATVRQHIRAEPFYWRLPQQFQGDQLMAYGGKLKYSVAFYS 1245
Query: 565 --PPGDSPLPVQLRLEGTGLALSLRHSSLSGPQD-AGHPREVELRFHLQETSEDVA-PPL 620
G S Q+ ++G + + + P++ +EV +R + + V+ P+
Sbjct: 1246 LDGVGTSNFEPQVLIKGGRIRKQVIYMDAPAPENGVRQEQEVAMRENFWKYFNSVSEKPV 1305
Query: 621 PPFHFQRLLANLTSLRLRVSPG----PSPAGPVFLTEVRLTSARPGLSPPASWVEICSCP 676
F +L+++ + ++ S G S + + R AS +E C CP
Sbjct: 1306 TREDFMSVLSDIEYILIKASYGQGLQQSRISDISMEVGRKAEKLHPEEEVASLLENCVCP 1365
Query: 677 TGYTGQFCESCAPGYKR-EMPQG---GP---YASCVPCTCNQHG-TCDPNTGICV-CSHH 727
G G C+ CAPGY R ++P G GP A CVPC+CN H TCDPNTG C+ C +
Sbjct: 1366 PGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDN 1425
Query: 728 TEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPE-----SREVVCTHCPPGQR 782
T G C+ C G+YG G A DC C CP + P + C C G
Sbjct: 1426 TAGDHCDVCTSGYYGK-VTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYE 1484
Query: 783 GRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDH 842
G+ CE C ++G+P G C +C C N + G+CD SG C+ C +G
Sbjct: 1485 GKHCERCSSSYYGNPQTPGG---SCQKCDC--NPHGSVHGDCDRTSGQCV-CRLGASGLR 1538
Query: 843 CEHCQ 847
C+ C+
Sbjct: 1539 CDECE 1543
Score = 157 bits (397), Expect = 8e-38
Identities = 107/352 (30%), Positives = 144/352 (40%), Gaps = 71/352 (20%)
Query: 675 CPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCN------QHGTCDPNTGICV-CSHH 727
C GY+G +CE CA GY G SCVPC C+ + G CD TG C+ C +
Sbjct: 819 CAPGYSGAWCERCADGYYGNPTVPGE--SCVPCDCSGNVDPSEAGHCDSVTGECLKCLGN 876
Query: 728 TEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCE 787
T+G CERC GFYG+ A A +C+ C C + + + + +C C P G++C+
Sbjct: 877 TDGAHCERCADGFYGD--AVTAKNCRACECHVKGSHSAVCHLETGLCD-CKPNVTGQQCD 933
Query: 788 VCDDGFFGDPLGLFGHPQPCH-------------QCQCSGNVD----------------- 817
C G++G G P C QC C V
Sbjct: 934 QCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDG 993
Query: 818 -------PNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHP 870
P+ CDP +G C+ C +T G CE C++G +G C C+C
Sbjct: 994 SCTPCDCPHTQNTCDPETGECV-CPPHTQGVKCEECEDGHWGYDAEVG----CQACNCSL 1048
Query: 871 QGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCH 930
GS + CD VTG C C R C +C G+ D C C C G+ D C+
Sbjct: 1049 VGSTHHR--CDVVTGHCQCKSKFGGRACDQCSLGYRDFPD---CVPCDCDLRGTSGDACN 1103
Query: 931 ---------PKTGQCTCRPGVTGQACDRCQLGFFGFSIK---GCRACRCSPL 970
+TG C C+ V G C+ C+ G F GC C CS L
Sbjct: 1104 LEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSGL 1155
Score = 135 bits (341), Expect = 2e-31
Identities = 73/222 (32%), Positives = 98/222 (44%), Gaps = 34/222 (15%)
Query: 271 CKCNGHA--SECG--PDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLP 326
C C+G+ SE G V G+ +C NT G CERC F G A A C
Sbjct: 849 CDCSGNVDPSEAGHCDSVTGE-CLKCLGNTDGAHCERCADGFY------GDAVTAKNCRA 901
Query: 327 CNCSGRSEECTFDRELFRSTGHGGRCH------HCRDHTAGPHCERCQENFYHWDPRMPC 380
C C + H CH C+ + G C++C +Y D C
Sbjct: 902 CECHVKGS-------------HSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGC 948
Query: 381 QPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDT 440
+PC+C AGS+ C D G C C P V G +CDRC GF++ +G C PC C + +T
Sbjct: 949 RPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDC--PHTQNT 1006
Query: 441 CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
CDP +G C C + +G C+ C G + GC +C C
Sbjct: 1007 CDPETGECVCPPHTQGVKCEECEDGHWGYDAE--VGCQACNC 1046
Score = 116 bits (291), Expect = 1e-25
Identities = 65/188 (34%), Positives = 86/188 (45%), Gaps = 21/188 (11%)
Query: 777 CPPGQRGRRCEVCDDGFFGD--PLGLFGHPQP----CHQCQCSGNVDPNAVGNCDPLSGH 830
CPPG G C+ C G+ P G P+P C C C+ + D CDP +G
Sbjct: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSD-----TCDPNTGK 1418
Query: 831 CLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTG----Q 886
CL C NT GDHC+ C G+YG A C C+C P + P + G +
Sbjct: 1419 CLNCGDNTAGDHCDVCTSGYYGKVTGS--ASDCALCAC-PHSPPASFSPTCVLEGDHDFR 1475
Query: 887 C-SCLPHVTARDCSRCYPGFFD--LQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVT 943
C +CL + C RC ++ PG C+ C C+P GS C +GQC CR G +
Sbjct: 1476 CDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGAS 1535
Query: 944 GQACDRCQ 951
G CD C+
Sbjct: 1536 GLRCDECE 1543
Score = 96.7 bits (239), Expect = 2e-19
Identities = 58/172 (33%), Positives = 74/172 (43%), Gaps = 14/172 (8%)
Query: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
C CN H+ C P+ L C NT G C+ C + + +A +C C C
Sbjct: 1403 CSCNNHSDTCDPNTGKCL--NCGDNTAGDHCDVCTSGYYGK-----VTGSASDCALCACP 1455
Query: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP---CQPCDCQS 387
S +F H RC C G HCERC ++Y +P+ P CQ CDC
Sbjct: 1456 -HSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYY-GNPQTPGGSCQKCDCNP 1513
Query: 388 AGSLHLQCDDT-GTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSL 438
GS+H CD T G C C+ +G +CD C P H L E C C G L
Sbjct: 1514 HGSVHGDCDRTSGQCVCRLGASGLRCDECEPR-HILMETDCVSCDDECVGVL 1564
Score = 95.1 bits (235), Expect = 5e-19
Identities = 60/213 (28%), Positives = 84/213 (39%), Gaps = 40/213 (18%)
Query: 290 CRCQHNTTGTDCERCLPFFQDRPWA----RGTAEAAHECLPCNCSGRSEECTFDRELFRS 345
C C T G C+ C P + RG C+PC+C+ S+ C
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCD-------- 1413
Query: 346 TGHGGRCHHCRDHTAGPHCERCQENFYH--WDPRMPCQPCDCQSA------------GSL 391
+ G+C +C D+TAG HC+ C +Y C C C + G
Sbjct: 1414 -PNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDH 1472
Query: 392 HLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSE---GGCRPCTCNPAGSLD-TCDPRSGR 447
+CD AC G C+RC ++ + G C+ C CNP GS+ CD SG+
Sbjct: 1473 DFRCD-----ACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQ 1527
Query: 448 CPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSC 480
C C+ G CD C P ++ C SC
Sbjct: 1528 CVCRLGASGLRCDECEPRHILME----TDCVSC 1556
Score = 92.0 bits (227), Expect = 4e-18
Identities = 159/726 (21%), Positives = 277/726 (38%), Gaps = 94/726 (12%)
Query: 834 CLHNTTGDHCEHCQEGFY------GSALAPRP-ADKCMPCSCHPQGSVSEQMPCDPVTGQ 886
C T G C+ C G++ GS PRP C+PCSC+ CDP TG+
Sbjct: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDT-----CDPNTGK 1418
Query: 887 C-SCLPHVTARDCSRCYPGFFDLQPGRG--CRSCKC--HPLGSQEDQCHPKTG---QC-T 937
C +C + C C G++ G C C C P S C + +C
Sbjct: 1419 CLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDA 1478
Query: 938 CRPGVTGQACDRCQLGFFGFSIK---GCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYK 993
C G G+ C+RC ++G C+ C C+P G+ C +G CVCR G G +
Sbjct: 1479 CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLR 1538
Query: 994 CDRCHDNFFLTADGTHCQQC-PSCYALVKEEA-----AKLKARLT----LTEGWLQGSDC 1043
CD C L T C C C ++ + A L LT + G L +
Sbjct: 1539 CDECEPRHILME--TDCVSCDDECVGVLLNDLDEIGDAVLSLNLTGIIPVPYGILSNLEN 1596
Query: 1044 GSPWGPLDILLGEAPRGDVYQGHHLLPGAREAF------LEQMMSLEGAVKAAREQLQRL 1097
+ + + LL E + D+ G L G E L +M++ V A E++ +
Sbjct: 1597 TTKY-LQESLLKENMQKDL--GKIKLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKE 1653
Query: 1098 NKGARCAQAGSQKTCTQLADLEAVLESSEEEILHAAAILASLEIPQEGPSQPTKWSHLAT 1157
++ A Q + T++ + + ++ +E+ L + L +++ Q G S
Sbjct: 1654 SQDLAIAIERLQMSITEIMEKTTLNQTLDEDFLLPNSTLQNMQ--QNGTSLLE-----IM 1706
Query: 1158 EARALARSHRDTATKIAATAWRALLASNTSYALLWNLLEGRVALETQRD-----LEDRYQ 1212
+ R + H++ ++ A A + + N + LE ++ L
Sbjct: 1707 QIRDFTQLHQNATLELKA-------AEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNN 1759
Query: 1213 EVQAAQKALRTAVAEVLPEAESVLATVQQVGADTAPYLALLASPGALPQKSRAEDLGLKA 1272
E++AA+ +R A A+ + E+ +L V + + + L + + GL
Sbjct: 1760 ELKAAEALVREAEAK-MQESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLID 1818
Query: 1273 KALEKTVA---SWQHMATEAARTLQTAAQATLRQTEPLTKLHQEARAALTQASSSVQAAT 1329
A +T A + +H+ + L +A+ +R +H R A+ + A
Sbjct: 1819 AAAAQTDAVQDALEHLEDHQDKLLLWSAK--IRHHIDDLVMHMSQRNAVDLVYRAEDHAA 1876
Query: 1330 VTVMGARTLLADLEGMKLQFPRPKDQAALQRKADSVSDRLLADTRKKTKQAERMLGNAAP 1389
A L + LE ++ A + S L+ ++ + + A R + +
Sbjct: 1877 EFQRLADVLYSGLENIRNVSLNATSAAYVHYNIQS----LIEESEELARDAHRTVTETSL 1932
Query: 1390 LSSSAKKKGREA----EVLAKDSAKLAKAL---LRERKQAHRRASRLTSQTQATLQQASQ 1442
LS S G+ A K+ L++ L E + + +R +Q ++
Sbjct: 1933 LSESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALELSELRNKTNRFQENAVEITRQTNE 1992
Query: 1443 QVLASEARRQELEEAERVGAGLSEMEQQIRESRISLEKDIETLS-ELLARLGSL------ 1495
+L A + + + GA E+ +S +S +D+ LS ELL SL
Sbjct: 1993 SLLILRAIPKGIRDK---GAKTKELATSASQSAVSTLRDVAGLSQELLNTSASLSRVNTT 2049
Query: 1496 --DTHQ 1499
+THQ
Sbjct: 2050 LRETHQ 2055
Score = 67.0 bits (162), Expect = 1e-10
Identities = 50/164 (30%), Positives = 65/164 (39%), Gaps = 33/164 (20%)
Query: 869 HPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFF--DLQPG--RG-------CRSC 917
HP+ V+ + C C P C C PG+ L G RG C C
Sbjct: 1350 HPEEEVASLLE------NCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPC 1403
Query: 918 KCHPLGSQEDQCHPKTGQC-TCRPGVTGQACDRCQLGFFGF---SIKGCRACRCSPLGAA 973
C+ + D C P TG+C C G CD C G++G S C C C A
Sbjct: 1404 SCN---NHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPA 1460
Query: 974 SAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCY 1017
S + TCV G ++CD C L +G HC++C S Y
Sbjct: 1461 SF----SPTCVLE-GDHDFRCDAC----LLGYEGKHCERCSSSY 1495
Score = 58.5 bits (140), Expect = 5e-08
Identities = 34/90 (37%), Positives = 41/90 (45%), Gaps = 17/90 (18%)
Query: 664 SPPASWVEIC-----------SCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQH 712
SPPAS+ C +C GY G+ CE C+ Y PQ P SC C CN H
Sbjct: 1457 SPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGN-PQT-PGGSCQKCDCNPH 1514
Query: 713 GT----CDPNTGICVCSHHTEGPSCERCLP 738
G+ CD +G CVC G C+ C P
Sbjct: 1515 GSVHGDCDRTSGQCVCRLGASGLRCDECEP 1544
Score = 40.4 bits (93), Expect = 0.014
Identities = 32/112 (28%), Positives = 41/112 (36%), Gaps = 11/112 (9%)
Query: 907 DLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACR 966
D+ G ++ K HP E++ C C PG G +C C G+ +
Sbjct: 1337 DISMEVGRKAEKLHP----EEEVASLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRG 1392
Query: 967 CSPLGAASAQCH-ENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCY 1017
PL A C N + C P KC C DN G HC C S Y
Sbjct: 1393 PRPLVAPCVPCSCNNHSDTCDPNTG--KCLNCGDN----TAGDHCDVCTSGY 1438
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 590 bits (1520), Expect = e-168
Identities = 391/1104 (35%), Positives = 531/1104 (48%), Gaps = 135/1104 (12%)
Query: 1 MAAAALLLGLALLAPRAAGAGMGACYDGAGRPQR-----------CLPVFENAAFGRLAQ 49
M AA +L L LL+ G+G A RPQ+ P N A L
Sbjct: 1 MPGAAGVLLLLLLS-----GGLGGVQ--AQRPQQQRQSQAHQQRGLFPAVLNLASNALIT 53
Query: 50 ASHTCGSP-PEDFCPHV----GAAGAGAHCQRCD--AADPQRHHNASYLTDFHSQDESTW 102
+ TCG PE +C V G C+ C+ +++P + H + D ++TW
Sbjct: 54 TNATCGEKGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAID----GKNTW 109
Query: 103 WQSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKFHTSRPESFAIYKRSRADGPWEPYQF 162
WQSPS+ G++Y V ITL L + ++I YV +K S I +RS D ++P+Q+
Sbjct: 110 WQSPSIKNGIEYHY-VTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQY 168
Query: 163 YSAS---CQKTYGRPEGQYLRPG-----EDERVAFCTSEFSDISPLSGGNVAFSTLEGRP 214
++ + C Y Y R G +D+ V CTS +S I PL G + S + GRP
Sbjct: 169 HAVTDTECLTLYNI----YPRTGPPSYAKDDEV-ICTSFYSKIHPLENGEIHISLINGRP 223
Query: 215 SAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIFK---------DPKVLQSYYYAVSDF 265
SA + SP L E+ ++ + + R+ T D+ DP V + YYY+V D
Sbjct: 224 SAD--DPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDI 281
Query: 266 SVGGRCKCNGHASECGPDVA-GQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHEC 324
SVGG C C GHA C D A + C C+HNT G C++C P F +PW GT EC
Sbjct: 282 SVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTEC 341
Query: 325 LPCNCSGRSEECTFDRELFRSTGH---------GGRCHHCRDHTAGPHCERCQENFYHWD 375
CNC G++EEC +D + R GG C +C +TAG +CE C + F+
Sbjct: 342 EACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPK 401
Query: 376 ------PRMPCQPCDCQSAGSLHLQC--DD--------TGTCACKPTVTGWKCDRCLPGF 419
PR PCQPC C GSL+ C D+ G+C CK G CDRC G+
Sbjct: 402 GVSPNYPR-PCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460
Query: 420 HSLSEGGCRPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSS 479
+ C+ C C+ GS + DP G C CKENVEG C RC+ G FNLQ N GC
Sbjct: 461 TGYPD--CKACNCSGLGSKNE-DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDE 517
Query: 480 CFCYGHSKVCASTAQFQVHHILSDFHQGAEGWWARSVGGS-EHPPQW----SPNGVLLSP 534
CFC G S C S+ + + + D GW+ + G PQ SP + +S
Sbjct: 518 CFCSGVSNRCQSS--YWTYGKIQDM----SGWYLTDLPGRIRVAPQQDDLDSPQQISISN 571
Query: 535 EDEEEL-------TAPEKFLGDQRFSYGQPLILTF------RVPPGDSPLPVQLRLEGTG 581
+ + +AP +LG++ + G L T + L + + LEG
Sbjct: 572 AEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMIILEGND 631
Query: 582 LALSLRHSSLSGPQDAGHPREVELRFHLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSP 641
L++S + H + L+ T P+ F +LANL + L+++
Sbjct: 632 LSISTAQDEVYLHPSEEHTNVLLLK-EESFTIHGTHFPVRRKEFMTVLANLKRVLLQITY 690
Query: 642 GPSPAGPVFLTEVRLTSA--RPGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGG 699
L+ V L SA P A+ VE+C CP GYTG CESC P ++R G
Sbjct: 691 SFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRR--VNGT 748
Query: 700 PYAS-CVPCTCNQHG-TCDPNTGICV-CSHHTEGPSCERCLPGFYGNPFAGQADDCQPCP 756
+ C PC C H +CD TG C+ C HT GP C++CLPGFYG P G ++DCQPC
Sbjct: 749 IFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCA 808
Query: 757 CP------GQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQC 810
CP S + S ++C CP G G RCE C +G+FG P G QP C
Sbjct: 809 CPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQP---C 865
Query: 811 QCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHP 870
QC+ N+D + G+CD LSG CL C TTG +CE C +G++G A+ A C PC C+
Sbjct: 866 QCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAV---DAKNCQPCRCNA 922
Query: 871 QGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCH 930
GS SE C TGQC C +V + C +C G F LQ RGC C C+ GS+ C
Sbjct: 923 GGSFSE--VCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCE 980
Query: 931 PKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCH-ENGTCVCRPGF 989
++GQC C+PGVTG+ CDRC G+F F GC AC CS LG C + G C+C P
Sbjct: 981 -ESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLG---NNCDPKTGRCICPPNT 1036
Query: 990 EGYKCDRCHDNFFLTADGTHCQQC 1013
G KC +C N + + T C+ C
Sbjct: 1037 IGEKCSKCAPNTWGHSITTGCKAC 1060
Score = 257 bits (657), Expect = 5e-68
Identities = 201/677 (29%), Positives = 280/677 (41%), Gaps = 133/677 (19%)
Query: 270 RCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGT--AEAAHECLPC 327
RC G SE GQ C C+ N G C++C GT ++A C+PC
Sbjct: 919 RCNAGGSFSEVCHSQTGQ--CECRANVQGQRCDKC---------KAGTFGLQSARGCVPC 967
Query: 328 NCSG---RSEECTFDRELFRSTGHGG----RCHH-------------------------- 354
NC+ +S +C + + G G RC H
Sbjct: 968 NCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKT 1027
Query: 355 ----CRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGSLHLQCD-DTGTCACKPTVTG 409
C +T G C +C N + C+ C+C + GSL QC+ +TG C C P +G
Sbjct: 1028 GRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSG 1087
Query: 410 WKCDRCLPGFHSLSEGGCRPC--------TCNPAGSLDTCDPRSGRCPCKENVEGNLCDR 461
KC C G + C TC+ +C ++G+C CK NVEG CDR
Sbjct: 1088 AKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDR 1147
Query: 462 CRPGTFNLQPHNPAGCSSCFCYGHSKVCASTAQF--------QVHHILSDFHQGAEGWWA 513
CRPG F L NP GCSSC+C+G + C+ IL + +
Sbjct: 1148 CRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDEALQHTTT 1207
Query: 514 RSVGGSEHPPQWSPNGVLLSPEDEEEL--TAPEKFLGDQRFSYGQPLILTF----RVPPG 567
+ + +HP + ++ E PE+F G + +YG L R G
Sbjct: 1208 KGIV-FQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFEAREETG 1266
Query: 568 DSPLPVQLRLEG---TGLALSLRHSSLSGPQDAGHPR-EVEL------------RFHLQE 611
S Q+ + G T + +RH ++ P R E+E+ R H
Sbjct: 1267 FSTYNPQVIIRGGTPTHARIIVRH--MAAPLIGQLTRHEIEMTEKEWKYYGDDPRVHRTV 1324
Query: 612 TSEDVAPPLPPFHFQRLLANLTSLRLRVSPGPSPAGPVFLTEVRLTSARPG----LSPPA 667
T ED L H+ + A + +R S ++E+ + A G ++PPA
Sbjct: 1325 TREDFLDILYDIHYILIKATYGNF-MRQSR---------ISEISMEVAEQGRGTTMTPPA 1374
Query: 668 SWVEICSCPTGYTGQFCESCAPGYKREMPQ------GGPYASCVPCTCNQHGT-CDPNTG 720
+E C CP GY+G CE+C PG+ R Q G +CVPC CN H + CDP T
Sbjct: 1375 DLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETS 1434
Query: 721 ICV-CSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPES------REVV 773
IC C HHT G CERC G+YG G +DCQ C CP S+ S +
Sbjct: 1435 ICQNCQHHTAGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYR 1493
Query: 774 CTHCPPGQRGRRCEVCDDGFFGDPLGLFGHP-QPCHQCQCSGNVDP--NAVGNCDPLSGH 830
CT CP G G+ CE C G+ G P G+P C +C+C DP + CDP++G
Sbjct: 1494 CTACPRGYEGQYCERCAPGYTGSP----GNPGGSCQECEC----DPYGSLPVPCDPVTGF 1545
Query: 831 CLRCLHNTTGDHCEHCQ 847
C C TG C+ C+
Sbjct: 1546 C-TCRPGATGRKCDGCK 1561
Score = 137 bits (346), Expect = 6e-32
Identities = 74/216 (34%), Positives = 102/216 (47%), Gaps = 22/216 (10%)
Query: 271 CKCNGHASECGPDVAGQLACRC---QHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPC 327
C+CN + P L+ C + TTG CE C + G A A C PC
Sbjct: 865 CQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYF------GDAVDAKNCQPC 918
Query: 328 NCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQS 387
C+ +F TG +C CR + G C++C+ + C PC+C S
Sbjct: 919 RCNAGG---SFSEVCHSQTG---QCE-CRANVQGQRCDKCKAGTFGLQSARGCVPCNCNS 971
Query: 388 AGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSGR 447
GS C+++G C C+P VTG KCDRC G+ + EGGC C C+ G + CDP++GR
Sbjct: 972 FGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLG--NNCDPKTGR 1029
Query: 448 CPCKENVEGNLCDRCRPGTFNLQPHN-PAGCSSCFC 482
C C N G C +C P T+ H+ GC +C C
Sbjct: 1030 CICPPNTIGEKCSKCAPNTWG---HSITTGCKACNC 1062
Score = 120 bits (300), Expect = 1e-26
Identities = 70/200 (35%), Positives = 90/200 (45%), Gaps = 19/200 (9%)
Query: 764 TTIPESREVVCTHCPPGQRGRRCEVCDDGFF---GDPLGLFGHPQ--PCHQCQCSGNVDP 818
T P + + CP G G CE C GF+ P G P C CQC+G+
Sbjct: 1369 TMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL 1428
Query: 819 NAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQM 878
CDP + C C H+T GD CE C G+YG + + C C+C S +
Sbjct: 1429 -----CDPETSICQNCQHHTAGDFCERCALGYYG--IVKGLPNDCQQCACPLISSSNNFS 1481
Query: 879 PCDPVTG----QCSCLPH-VTARDCSRCYPGFFDL--QPGRGCRSCKCHPLGSQEDQCHP 931
P G +C+ P + C RC PG+ PG C+ C+C P GS C P
Sbjct: 1482 PSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDP 1541
Query: 932 KTGQCTCRPGVTGQACDRCQ 951
TG CTCRPG TG+ CD C+
Sbjct: 1542 VTGFCTCRPGATGRKCDGCK 1561
Score = 108 bits (269), Expect = 5e-23
Identities = 170/733 (23%), Positives = 275/733 (37%), Gaps = 149/733 (20%)
Query: 834 CLHNTTGDHCEHCQEGFYG-----SALAPRPA-DKCMPCSCHPQGSVSEQMPCDPVTGQC 887
C +G CE C GFY P P C+PC C+ S+ CDP T C
Sbjct: 1382 CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL-----CDPETSIC 1436
Query: 888 SCLPHVTARD-CSRCYPGFFDLQPG--RGCRSCKCHPLGSQEDQCHPKTG-------QCT 937
H TA D C RC G++ + G C+ C C PL S + P +CT
Sbjct: 1437 QNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCAC-PLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 938 -CRPGVTGQACDRCQLGFFGFSIK---GCRACRCSPLGAASAQCHE-NGTCVCRPGFEGY 992
C G GQ C+RC G+ G C+ C C P G+ C G C CRPG G
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 993 KCDRCHDNFFLTADGTHCQQCPSCYALVKEEAAKLKARLTLTEGWLQGSDCGSPWGPLDI 1052
KCD C + +G C C G +C +
Sbjct: 1556 KCDGC--KHWHAREGWECVFC--------------------------GDEC------TGL 1581
Query: 1053 LLGEAPRGDVYQGHHLLPGAREAFLEQMMSLEGAVKAAREQLQRLNKGARCAQAGSQKTC 1112
LLG+ R + L G A + + LE + + L R Q
Sbjct: 1582 LLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELKHLLSPQRAPERLIQLAEGNLN 1641
Query: 1113 TQLADLEAVLESSEEEILHAAAILASLEIPQEGPSQPTKWSHLATEARALARSHRDTATK 1172
T + ++ +L + ++ +G T A++L ++ A
Sbjct: 1642 TLVTEMNELL-------------TRATKVTADGEQTGQDAERTNTRAKSLGEFIKELARD 1688
Query: 1173 IAATAWRALLASNTSYALLWNLLEGRVALETQRDLEDRYQEVQAAQKALRTAVAEVLPEA 1232
A +A+ + T G +R+LE +E+ K LR E E
Sbjct: 1689 AEAVNEKAIKLNETL---------GTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE- 1738
Query: 1233 ESVLATVQQVGADTAPYLALLASPGALPQKSRAEDLGLKAKALEKTVASWQHMATEAART 1292
+A + V A+ ALL L +SR E+ ++ K L + +A +++ +A
Sbjct: 1739 ---IAEDELVAAE-----ALLKKVKKLFGESRGENEEME-KDLREKLADYKNKVDDAWDL 1789
Query: 1293 LQTAAQATLRQTEPLTKLHQEARAALTQASSSVQAAT----------VTVMGARTLLAD- 1341
L+ A +R+ L ++Q+ AL + +V++ ++ LAD
Sbjct: 1790 LREATD-KIREANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADE 1848
Query: 1342 -------LEGMKLQFPRPKDQAALQRKADSVS----DRLLADTRKKTKQAERMLGNAAPL 1390
+E ++ + P ++ L K D +S DR LA+ K QAE +AA L
Sbjct: 1849 INSIIDYVEDIQTKLPPMSEE--LNDKIDDLSQEIKDRKLAE---KVSQAE---SHAAQL 1900
Query: 1391 S-SSAKKKG--REAEVLA-------------KDSAKLAKALLRERKQAHRRASRLTSQTQ 1434
+ SSA G EA+ ++ KD A+ + +E K A++L + +
Sbjct: 1901 NDSSAVLDGILDEAKNISFNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPR 1960
Query: 1435 ATLQQASQQVLASEARRQELEEAERVGAGLSEMEQQIRESRISLEKD-------IETLSE 1487
L++ ++ L R L EA+++ + E E + + +E + TL++
Sbjct: 1961 GLLKEDAKGCLQKSFR--ILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLND 2018
Query: 1488 LLARLGSLDTHQA 1500
L +L ++ A
Sbjct: 2019 TLGKLSAIPNDTA 2031
Score = 32.7 bits (73), Expect = 2.8
Identities = 42/187 (22%), Positives = 82/187 (43%), Gaps = 10/187 (5%)
Query: 1368 RLLADTRKKTKQAERMLGNAAPLSSSAKKKGREAEVLAKDSAKLAKALLRERKQAHRRAS 1427
++ AD + + AER A L K+ R+AE + + + KL + L + R
Sbjct: 1656 KVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLE 1715
Query: 1428 RLTSQTQATLQQASQQVLASEARRQELEEAERVGAG--LSEMEQQIRESRISLEKDIETL 1485
L + +++ ++ L ++ +E+ E E V A L ++++ ESR E+ + L
Sbjct: 1716 GLQKEIDQMIKELRRKNLETQ---KEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDL 1772
Query: 1486 SELLARLGSLDTHQAPAQALNETQWALERLRLQLGSPGSLQRKLSLLEQESQQQELQIQG 1545
E LA D A + + A +++R Q+ ++ LE++ + E +
Sbjct: 1773 REKLA-----DYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKKEAVESGKRQ 1827
Query: 1546 FESDLAE 1552
E+ L E
Sbjct: 1828 IENTLKE 1834
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 590 bits (1520), Expect = e-168
Identities = 391/1104 (35%), Positives = 531/1104 (48%), Gaps = 135/1104 (12%)
Query: 1 MAAAALLLGLALLAPRAAGAGMGACYDGAGRPQR-----------CLPVFENAAFGRLAQ 49
M AA +L L LL+ G+G A RPQ+ P N A L
Sbjct: 1 MPGAAGVLLLLLLS-----GGLGGVQ--AQRPQQQRQSQAHQQRGLFPAVLNLASNALIT 53
Query: 50 ASHTCGSP-PEDFCPHV----GAAGAGAHCQRCD--AADPQRHHNASYLTDFHSQDESTW 102
+ TCG PE +C V G C+ C+ +++P + H + D ++TW
Sbjct: 54 TNATCGEKGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAID----GKNTW 109
Query: 103 WQSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKFHTSRPESFAIYKRSRADGPWEPYQF 162
WQSPS+ G++Y V ITL L + ++I YV +K S I +RS D ++P+Q+
Sbjct: 110 WQSPSIKNGIEYHY-VTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVEYKPWQY 168
Query: 163 YSAS---CQKTYGRPEGQYLRPG-----EDERVAFCTSEFSDISPLSGGNVAFSTLEGRP 214
++ + C Y Y R G +D+ V CTS +S I PL G + S + GRP
Sbjct: 169 HAVTDTECLTLYNI----YPRTGPPSYAKDDEV-ICTSFYSKIHPLENGEIHISLINGRP 223
Query: 215 SAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIFK---------DPKVLQSYYYAVSDF 265
SA + SP L E+ ++ + + R+ T D+ DP V + YYY+V D
Sbjct: 224 SAD--DPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKDI 281
Query: 266 SVGGRCKCNGHASECGPDVA-GQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHEC 324
SVGG C C GHA C D A + C C+HNT G C++C P F +PW GT EC
Sbjct: 282 SVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTEC 341
Query: 325 LPCNCSGRSEECTFDRELFRSTGH---------GGRCHHCRDHTAGPHCERCQENFYHWD 375
CNC G++EEC +D + R GG C +C +TAG +CE C + F+
Sbjct: 342 EACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPK 401
Query: 376 ------PRMPCQPCDCQSAGSLHLQC--DD--------TGTCACKPTVTGWKCDRCLPGF 419
PR PCQPC C GSL+ C D+ G+C CK G CDRC G+
Sbjct: 402 GVSPNYPR-PCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGY 460
Query: 420 HSLSEGGCRPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSS 479
+ C+ C C+ GS + DP G C CKENVEG C RC+ G FNLQ N GC
Sbjct: 461 TGYPD--CKACNCSGLGSKNE-DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDE 517
Query: 480 CFCYGHSKVCASTAQFQVHHILSDFHQGAEGWWARSVGGS-EHPPQW----SPNGVLLSP 534
CFC G S C S+ + + + D GW+ + G PQ SP + +S
Sbjct: 518 CFCSGVSNRCQSS--YWTYGKIQDM----SGWYLTDLPGRIRVAPQQDDLDSPQQISISN 571
Query: 535 EDEEEL-------TAPEKFLGDQRFSYGQPLILTF------RVPPGDSPLPVQLRLEGTG 581
+ + +AP +LG++ + G L T + L + + LEG
Sbjct: 572 AEARQALPHSYYWSAPAPYLGNKLPAVGGQLTFTISYDLEEEEEDTERVLQLMIILEGND 631
Query: 582 LALSLRHSSLSGPQDAGHPREVELRFHLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSP 641
L++S + H + L+ T P+ F +LANL + L+++
Sbjct: 632 LSISTAQDEVYLHPSEEHTNVLLLK-EESFTIHGTHFPVRRKEFMTVLANLKRVLLQITY 690
Query: 642 GPSPAGPVFLTEVRLTSA--RPGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGG 699
L+ V L SA P A+ VE+C CP GYTG CESC P ++R G
Sbjct: 691 SFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRR--VNGT 748
Query: 700 PYAS-CVPCTCNQHG-TCDPNTGICV-CSHHTEGPSCERCLPGFYGNPFAGQADDCQPCP 756
+ C PC C H +CD TG C+ C HT GP C++CLPGFYG P G ++DCQPC
Sbjct: 749 IFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCA 808
Query: 757 CP------GQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQC 810
CP S + S ++C CP G G RCE C +G+FG P G QP C
Sbjct: 809 CPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQP---C 865
Query: 811 QCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHP 870
QC+ N+D + G+CD LSG CL C TTG +CE C +G++G A+ A C PC C+
Sbjct: 866 QCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAV---DAKNCQPCRCNA 922
Query: 871 QGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCH 930
GS SE C TGQC C +V + C +C G F LQ RGC C C+ GS+ C
Sbjct: 923 GGSFSE--VCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCE 980
Query: 931 PKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCH-ENGTCVCRPGF 989
++GQC C+PGVTG+ CDRC G+F F GC AC CS LG C + G C+C P
Sbjct: 981 -ESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLG---NNCDPKTGRCICPPNT 1036
Query: 990 EGYKCDRCHDNFFLTADGTHCQQC 1013
G KC +C N + + T C+ C
Sbjct: 1037 IGEKCSKCAPNTWGHSITTGCKAC 1060
Score = 257 bits (657), Expect = 5e-68
Identities = 201/677 (29%), Positives = 280/677 (41%), Gaps = 133/677 (19%)
Query: 270 RCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGT--AEAAHECLPC 327
RC G SE GQ C C+ N G C++C GT ++A C+PC
Sbjct: 919 RCNAGGSFSEVCHSQTGQ--CECRANVQGQRCDKC---------KAGTFGLQSARGCVPC 967
Query: 328 NCSG---RSEECTFDRELFRSTGHGG----RCHH-------------------------- 354
NC+ +S +C + + G G RC H
Sbjct: 968 NCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKT 1027
Query: 355 ----CRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGSLHLQCD-DTGTCACKPTVTG 409
C +T G C +C N + C+ C+C + GSL QC+ +TG C C P +G
Sbjct: 1028 GRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSG 1087
Query: 410 WKCDRCLPGFHSLSEGGCRPC--------TCNPAGSLDTCDPRSGRCPCKENVEGNLCDR 461
KC C G + C TC+ +C ++G+C CK NVEG CDR
Sbjct: 1088 AKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDR 1147
Query: 462 CRPGTFNLQPHNPAGCSSCFCYGHSKVCASTAQF--------QVHHILSDFHQGAEGWWA 513
CRPG F L NP GCSSC+C+G + C+ IL + +
Sbjct: 1148 CRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDEALQHTTT 1207
Query: 514 RSVGGSEHPPQWSPNGVLLSPEDEEEL--TAPEKFLGDQRFSYGQPLILTF----RVPPG 567
+ + +HP + ++ E PE+F G + +YG L R G
Sbjct: 1208 KGIV-FQHPEIVAHMDLMREDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFEAREETG 1266
Query: 568 DSPLPVQLRLEG---TGLALSLRHSSLSGPQDAGHPR-EVEL------------RFHLQE 611
S Q+ + G T + +RH ++ P R E+E+ R H
Sbjct: 1267 FSTYNPQVIIRGGTPTHARIIVRH--MAAPLIGQLTRHEIEMTEKEWKYYGDDPRVHRTV 1324
Query: 612 TSEDVAPPLPPFHFQRLLANLTSLRLRVSPGPSPAGPVFLTEVRLTSARPG----LSPPA 667
T ED L H+ + A + +R S ++E+ + A G ++PPA
Sbjct: 1325 TREDFLDILYDIHYILIKATYGNF-MRQSR---------ISEISMEVAEQGRGTTMTPPA 1374
Query: 668 SWVEICSCPTGYTGQFCESCAPGYKREMPQ------GGPYASCVPCTCNQHGT-CDPNTG 720
+E C CP GY+G CE+C PG+ R Q G +CVPC CN H + CDP T
Sbjct: 1375 DLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETS 1434
Query: 721 ICV-CSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPES------REVV 773
IC C HHT G CERC G+YG G +DCQ C CP S+ S +
Sbjct: 1435 ICQNCQHHTAGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYR 1493
Query: 774 CTHCPPGQRGRRCEVCDDGFFGDPLGLFGHP-QPCHQCQCSGNVDP--NAVGNCDPLSGH 830
CT CP G G+ CE C G+ G P G+P C +C+C DP + CDP++G
Sbjct: 1494 CTACPRGYEGQYCERCAPGYTGSP----GNPGGSCQECEC----DPYGSLPVPCDPVTGF 1545
Query: 831 CLRCLHNTTGDHCEHCQ 847
C C TG C+ C+
Sbjct: 1546 C-TCRPGATGRKCDGCK 1561
Score = 137 bits (346), Expect = 6e-32
Identities = 74/216 (34%), Positives = 102/216 (47%), Gaps = 22/216 (10%)
Query: 271 CKCNGHASECGPDVAGQLACRC---QHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPC 327
C+CN + P L+ C + TTG CE C + G A A C PC
Sbjct: 865 CQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYF------GDAVDAKNCQPC 918
Query: 328 NCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQS 387
C+ +F TG +C CR + G C++C+ + C PC+C S
Sbjct: 919 RCNAGG---SFSEVCHSQTG---QCE-CRANVQGQRCDKCKAGTFGLQSARGCVPCNCNS 971
Query: 388 AGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSGR 447
GS C+++G C C+P VTG KCDRC G+ + EGGC C C+ G + CDP++GR
Sbjct: 972 FGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLG--NNCDPKTGR 1029
Query: 448 CPCKENVEGNLCDRCRPGTFNLQPHN-PAGCSSCFC 482
C C N G C +C P T+ H+ GC +C C
Sbjct: 1030 CICPPNTIGEKCSKCAPNTWG---HSITTGCKACNC 1062
Score = 120 bits (300), Expect = 1e-26
Identities = 70/200 (35%), Positives = 90/200 (45%), Gaps = 19/200 (9%)
Query: 764 TTIPESREVVCTHCPPGQRGRRCEVCDDGFF---GDPLGLFGHPQ--PCHQCQCSGNVDP 818
T P + + CP G G CE C GF+ P G P C CQC+G+
Sbjct: 1369 TMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL 1428
Query: 819 NAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQM 878
CDP + C C H+T GD CE C G+YG + + C C+C S +
Sbjct: 1429 -----CDPETSICQNCQHHTAGDFCERCALGYYG--IVKGLPNDCQQCACPLISSSNNFS 1481
Query: 879 PCDPVTG----QCSCLPH-VTARDCSRCYPGFFDL--QPGRGCRSCKCHPLGSQEDQCHP 931
P G +C+ P + C RC PG+ PG C+ C+C P GS C P
Sbjct: 1482 PSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDP 1541
Query: 932 KTGQCTCRPGVTGQACDRCQ 951
TG CTCRPG TG+ CD C+
Sbjct: 1542 VTGFCTCRPGATGRKCDGCK 1561
Score = 108 bits (269), Expect = 5e-23
Identities = 170/733 (23%), Positives = 275/733 (37%), Gaps = 149/733 (20%)
Query: 834 CLHNTTGDHCEHCQEGFYG-----SALAPRPA-DKCMPCSCHPQGSVSEQMPCDPVTGQC 887
C +G CE C GFY P P C+PC C+ S+ CDP T C
Sbjct: 1382 CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL-----CDPETSIC 1436
Query: 888 SCLPHVTARD-CSRCYPGFFDLQPG--RGCRSCKCHPLGSQEDQCHPKTG-------QCT 937
H TA D C RC G++ + G C+ C C PL S + P +CT
Sbjct: 1437 QNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCAC-PLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 938 -CRPGVTGQACDRCQLGFFGFSIK---GCRACRCSPLGAASAQCHE-NGTCVCRPGFEGY 992
C G GQ C+RC G+ G C+ C C P G+ C G C CRPG G
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 993 KCDRCHDNFFLTADGTHCQQCPSCYALVKEEAAKLKARLTLTEGWLQGSDCGSPWGPLDI 1052
KCD C + +G C C G +C +
Sbjct: 1556 KCDGC--KHWHAREGWECVFC--------------------------GDEC------TGL 1581
Query: 1053 LLGEAPRGDVYQGHHLLPGAREAFLEQMMSLEGAVKAAREQLQRLNKGARCAQAGSQKTC 1112
LLG+ R + L G A + + LE + + L R Q
Sbjct: 1582 LLGDLARLEQMVMSINLTGPLPAPYKMLYGLENMTQELKHLLSPQRAPERLIQLAEGNLN 1641
Query: 1113 TQLADLEAVLESSEEEILHAAAILASLEIPQEGPSQPTKWSHLATEARALARSHRDTATK 1172
T + ++ +L + ++ +G T A++L ++ A
Sbjct: 1642 TLVTEMNELL-------------TRATKVTADGEQTGQDAERTNTRAKSLGEFIKELARD 1688
Query: 1173 IAATAWRALLASNTSYALLWNLLEGRVALETQRDLEDRYQEVQAAQKALRTAVAEVLPEA 1232
A +A+ + T G +R+LE +E+ K LR E E
Sbjct: 1689 AEAVNEKAIKLNETL---------GTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKE- 1738
Query: 1233 ESVLATVQQVGADTAPYLALLASPGALPQKSRAEDLGLKAKALEKTVASWQHMATEAART 1292
+A + V A+ ALL L +SR E+ ++ K L + +A +++ +A
Sbjct: 1739 ---IAEDELVAAE-----ALLKKVKKLFGESRGENEEME-KDLREKLADYKNKVDDAWDL 1789
Query: 1293 LQTAAQATLRQTEPLTKLHQEARAALTQASSSVQAAT----------VTVMGARTLLAD- 1341
L+ A +R+ L ++Q+ AL + +V++ ++ LAD
Sbjct: 1790 LREATD-KIREANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADE 1848
Query: 1342 -------LEGMKLQFPRPKDQAALQRKADSVS----DRLLADTRKKTKQAERMLGNAAPL 1390
+E ++ + P ++ L K D +S DR LA+ K QAE +AA L
Sbjct: 1849 INSIIDYVEDIQTKLPPMSEE--LNDKIDDLSQEIKDRKLAE---KVSQAE---SHAAQL 1900
Query: 1391 S-SSAKKKG--REAEVLA-------------KDSAKLAKALLRERKQAHRRASRLTSQTQ 1434
+ SSA G EA+ ++ KD A+ + +E K A++L + +
Sbjct: 1901 NDSSAVLDGILDEAKNISFNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPR 1960
Query: 1435 ATLQQASQQVLASEARRQELEEAERVGAGLSEMEQQIRESRISLEKD-------IETLSE 1487
L++ ++ L R L EA+++ + E E + + +E + TL++
Sbjct: 1961 GLLKEDAKGCLQKSFR--ILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLND 2018
Query: 1488 LLARLGSLDTHQA 1500
L +L ++ A
Sbjct: 2019 TLGKLSAIPNDTA 2031
Score = 32.7 bits (73), Expect = 2.8
Identities = 42/187 (22%), Positives = 82/187 (43%), Gaps = 10/187 (5%)
Query: 1368 RLLADTRKKTKQAERMLGNAAPLSSSAKKKGREAEVLAKDSAKLAKALLRERKQAHRRAS 1427
++ AD + + AER A L K+ R+AE + + + KL + L + R
Sbjct: 1656 KVTADGEQTGQDAERTNTRAKSLGEFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLE 1715
Query: 1428 RLTSQTQATLQQASQQVLASEARRQELEEAERVGAG--LSEMEQQIRESRISLEKDIETL 1485
L + +++ ++ L ++ +E+ E E V A L ++++ ESR E+ + L
Sbjct: 1716 GLQKEIDQMIKELRRKNLETQ---KEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDL 1772
Query: 1486 SELLARLGSLDTHQAPAQALNETQWALERLRLQLGSPGSLQRKLSLLEQESQQQELQIQG 1545
E LA D A + + A +++R Q+ ++ LE++ + E +
Sbjct: 1773 REKLA-----DYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKKEAVESGKRQ 1827
Query: 1546 FESDLAE 1552
E+ L E
Sbjct: 1828 IENTLKE 1834
>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
Length = 1111
Score = 565 bits (1456), Expect = e-160
Identities = 278/608 (45%), Positives = 356/608 (58%), Gaps = 27/608 (4%)
Query: 304 CLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPH 363
CL F P AR T+ C+C+G+S +C FDREL R TG+G RC +C D+T G H
Sbjct: 9 CLCFSLLLPAARATSRRE----VCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIH 64
Query: 364 CERCQENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLS 423
CE+C+ FY R C PC+C S GSL +CD++G C+CKP VTG +CDRCLPGFH L+
Sbjct: 65 CEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLT 124
Query: 424 EGGCRP--------CTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPA 475
+ GC C C+PAG CD +GRC CK V G CDRCR G +NL NP
Sbjct: 125 DAGCTQDQRLLDSKCDCDPAGIAGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPE 182
Query: 476 GCSSCFCYGHSKVCASTAQFQVHHILSDFHQGAEGWWARSVGGSEHPPQWSPN--GVLLS 533
GC+ CFCYGHS C S+A++ VH I S FHQ +GW A GS QWS V S
Sbjct: 183 GCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVFSS 242
Query: 534 PE--DEEELTAPEKFLGDQRFSYGQPLILTFRVPPGDS-PLPVQLRLEGTGLALSLRHSS 590
+ D AP KFLG+Q+ SYGQ L +RV G P + LEG GL ++
Sbjct: 243 AQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPLMP 302
Query: 591 LSGPQDAGHPREVELRFHLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSPGPSPAGPVF 650
L G + R + + S + +P L F ++RLL NLT+LR+R + G G +
Sbjct: 303 LGKTLPCGLTKTYTFRLN-EHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTG--Y 359
Query: 651 LTEVRLTSARPGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCN 710
+ V L SARP PA WVE C CP GY GQFC+ CA GYKR+ + GP+ +C+PC C
Sbjct: 360 IDNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQ 419
Query: 711 QHGTCDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESR 770
G CDP+TG C C C GFY +P ++ C+PCPC +C+ +PE+
Sbjct: 420 GGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRS--CKPCPCHNGFSCSVMPETE 477
Query: 771 EVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGH 830
EVVC +CPPG G RCE+C DG+FGDP G G +PC CQC+ NVDP+A GNCD L+G
Sbjct: 478 EVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGR 537
Query: 831 CLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCL 890
CL+C+HNT G +C+ C+ G++G LAP PADKC C+C+P G SE + C G C C
Sbjct: 538 CLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG--SEPVGCRS-DGTCVCK 594
Query: 891 PHVTARDC 898
P +C
Sbjct: 595 PGFGGPNC 602
Score = 182 bits (462), Expect = 2e-45
Identities = 188/762 (24%), Positives = 304/762 (39%), Gaps = 80/762 (10%)
Query: 777 CPPGQRGRRCEVCDDGFFGDP--LGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRC 834
CP G +G+ C+ C G+ D LG FG C C C G G CDP +G C
Sbjct: 384 CPVGYKGQFCQDCASGYKRDSARLGPFG---TCIPCNCQGG------GACDPDTGDCYSG 434
Query: 835 LHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVT 894
N + C C GFY PR C PC CH S S + V +C P VT
Sbjct: 435 DENPDIE-CADCPIGFYNDPHDPR---SCKPCPCHNGFSCSVMPETEEVVCN-NCPPGVT 489
Query: 895 ARDCSRCYPGFF-----DLQPGRGCRSCKCHPL--GSQEDQCHPKTGQCT-CRPGVTGQA 946
C C G+F + P R C+ C+C+ S C TG+C C G
Sbjct: 490 GARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIY 549
Query: 947 CDRCQLGFFGFSIKG-----CRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNF 1001
CD+C+ G+FG + CRAC C+P+G+ C +GTCVC+PGF G C+ H F
Sbjct: 550 CDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE--HGAF 607
Query: 1002 FLTADGTHCQQCPSCYALVKEEAAKLKARLTLTEGWL---QGSDCGSPWGPLDILLGEAP 1058
CP+CY VK + + +L E + QG D P L+ + +A
Sbjct: 608 ----------SCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAE 657
Query: 1059 RG--DVYQGHHLLPGAREAFLEQMMSLEGAVKAAREQLQRLNKGARCAQAGSQKTCTQLA 1116
+ D+ + + GA + Q+ + + + +L L +A + ++
Sbjct: 658 QALQDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVR 717
Query: 1117 DLEAVLESSEEEILHAAAILASLEIP-QEGPSQPTKWSHLATEARALARSHRDTATKIAA 1175
D ++ + + + A L + IP + P + LA EA LA SH ++A+ +
Sbjct: 718 DTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQ 777
Query: 1176 TAWRALLASNTSYALLWNLL-----------EGRVALETQRDLEDRYQEVQAAQKALRTA 1224
S + +L+ L +G V LE Q + A
Sbjct: 778 LTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQA 837
Query: 1225 VAEVLPEAESVLATVQQVGADTAPYLALLASPGALPQKSRAEDLGL-------KAKALEK 1277
E + L + V A K +A+ L + K +K
Sbjct: 838 EIEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQK 897
Query: 1278 TVASWQHMATEAARTLQTAAQATLRQTEPLTKLHQEARAALTQASSSVQAATVTVMGART 1337
+ +W+ EA + LQ + + L++ A A ++A ++ T +
Sbjct: 898 NLGNWKE---EAQQLLQNGKSGREKSDQLLSR----ANLAKSRAQEALSMGNATFYEVES 950
Query: 1338 LLADLEGMKLQFPRPKDQAALQRKADSVSDRLLADTRKKTKQAERMLGNAAPLSSSAKKK 1397
+L +L LQ K +A K S + ++D KT+QAER LG+AA + AK
Sbjct: 951 ILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNG 1010
Query: 1398 GREAEVLAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQASQQVLASEARRQELE-- 1455
EA ++ + + +L E A + + A+L+ ++V E R+ELE
Sbjct: 1011 AGEALEISSEIEQEIGSLNLEANVTADGALAM-EKGLASLKSEMREV-EGELERKELEFD 1068
Query: 1456 ----EAERVGAGLSEMEQQIRESRISLEKDIETLSELLARLG 1493
+ V +++ + + + ++++ + TL LL +G
Sbjct: 1069 TNMDAVQMVITEAQKVDTRAKNAGVTIQDTLNTLDGLLHLMG 1110
Score = 115 bits (288), Expect = 3e-25
Identities = 62/148 (41%), Positives = 80/148 (54%), Gaps = 22/148 (14%)
Query: 831 CLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCL 890
CL C NT G HCE C+ GFY R D+C+PC+C+ +GS+S + CD +G+CSC
Sbjct: 53 CLNCNDNTDGIHCEKCKNGFYRH----RERDRCLPCNCNSKGSLSAR--CDN-SGRCSCK 105
Query: 891 PHVTARDCSRCYPGFFDLQPGRGC--------RSCKCHPLGSQEDQCHPKTGQCTCRPGV 942
P VT C RC PGF L GC C C P G C G+C C+P V
Sbjct: 106 PGVTGARCDRCLPGFHMLTDA-GCTQDQRLLDSKCDCDPAGI-AGPC--DAGRCVCKPAV 161
Query: 943 TGQACDRCQLGFF---GFSIKGCRACRC 967
TG+ CDRC+ G++ G + +GC C C
Sbjct: 162 TGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 94.7 bits (234), Expect = 6e-19
Identities = 53/177 (29%), Positives = 78/177 (44%), Gaps = 22/177 (12%)
Query: 888 SCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQAC 947
+C + C +C GF+ + C C C+ GS +C +G+C+C+PGVTG C
Sbjct: 55 NCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCD-NSGRCSCKPGVTGARC 113
Query: 948 DRCQLGFFGFSIKGC--------RACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHD 999
DRC GF + GC C C P G A C + G CVC+P G +CDRC
Sbjct: 114 DRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA-GPC-DAGRCVCKPAVTGERCDRCRS 171
Query: 1000 NFFLTADGTHCQQCPSCYALVKEEAAKLKARLTL----------TEGWLQGSDCGSP 1046
++ DG + + C C+ + + A ++ +GW GSP
Sbjct: 172 GYY-NLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSP 227
Score = 74.3 bits (181), Expect = 9e-13
Identities = 49/152 (32%), Positives = 63/152 (41%), Gaps = 19/152 (12%)
Query: 774 CTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLR 833
C +C G CE C +GF+ C C C+ +A CD SG C
Sbjct: 53 CLNCNDNTDGIHCEKCKNGFYRHR-----ERDRCLPCNCNSKGSLSA--RCDN-SGRC-S 103
Query: 834 CLHNTTGDHCEHCQEGFYGSALAPRPADKCM---PCSCHPQGSVSEQMPCDPVTGQCSCL 890
C TG C+ C GF+ A D+ + C C P G PCD G+C C
Sbjct: 104 CKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAG---PCD--AGRCVCK 158
Query: 891 PHVTARDCSRCYPGFFDLQPG--RGCRSCKCH 920
P VT C RC G+++L G GC C C+
Sbjct: 159 PAVTGERCDRCRSGYYNLDGGNPEGCTQCFCY 190
Score = 73.2 bits (178), Expect = 2e-12
Identities = 45/149 (30%), Positives = 63/149 (42%), Gaps = 13/149 (8%)
Query: 271 CKC-NGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC 329
C C NG + P+ + C TG CE C + P+ G C PC C
Sbjct: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQC 519
Query: 330 SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP-----CQPCD 384
+ + R TG RC C +TAG +C++C+ ++ DP P C+ C+
Sbjct: 520 NNNVDPSA-SGNCDRLTG---RCLKCIHNTAGIYCDQCKAGYFG-DPLAPNPADKCRACN 574
Query: 385 CQSAGSLHLQCDDTGTCACKPTVTGWKCD 413
C GS + C GTC CKP G C+
Sbjct: 575 CNPMGSEPVGCRSDGTCVCKPGFGGPNCE 603
Score = 72.8 bits (177), Expect = 2e-12
Identities = 65/254 (25%), Positives = 83/254 (32%), Gaps = 41/254 (16%)
Query: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
C C G + C PD C +C C F + P C PC C
Sbjct: 416 CNCQGGGA-CDPDTGD---CYSGDENPDIECADCPIGFYNDP------HDPRSCKPCPCH 465
Query: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFY-----HWDPRMPCQPCDC 385
C+ E C++C G CE C + ++ P PCQPC C
Sbjct: 466 N-GFSCSVMPETEEVV-----CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC 519
Query: 386 QSA--GSLHLQCDD-TGTCA-CKPTVTGWKCDRCLPGFHS-----LSEGGCRPCTCNPAG 436
+ S CD TG C C G CD+C G+ CR C CNP G
Sbjct: 520 NNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG 579
Query: 437 SLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVCASTAQFQ 496
S G C CK G C+ H C +C+ ++ Q Q
Sbjct: 580 SEPVGCRSDGTCVCKPGFGGPNCE-----------HGAFSCPACYNQVKIQMDQFMQQLQ 628
Query: 497 VHHILSDFHQGAEG 510
L QG +G
Sbjct: 629 RMEALISKAQGGDG 642
Score = 64.3 bits (155), Expect = 9e-10
Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 8/98 (8%)
Query: 917 CKCHPLGSQ---EDQCHPKTGQ----CTCRPGVTGQACDRCQLGFFGFSIKG-CRACRCS 968
C C+ Q + + H +TG C G C++C+ GF+ + C C C+
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCN 87
Query: 969 PLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTAD 1006
G+ SA+C +G C C+PG G +CDRC F + D
Sbjct: 88 SKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTD 125
Score = 49.3 bits (116), Expect = 3e-05
Identities = 36/120 (30%), Positives = 49/120 (40%), Gaps = 19/120 (15%)
Query: 271 CKCNGHAS-ECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC 329
C CN S D +G+ C C+ TG C+RCLP F A T + C+C
Sbjct: 84 CNCNSKGSLSARCDNSGR--CSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDC 141
Query: 330 --SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--CQPCDC 385
+G + C GRC C+ G C+RC+ +Y+ D P C C C
Sbjct: 142 DPAGIAGPC-----------DAGRC-VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 40.4 bits (93), Expect = 0.014
Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 5/64 (7%)
Query: 675 CPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGTCDP----NTGICVCSHHTEG 730
C G +C+ C GY + P C C CN G+ +P + G CVC G
Sbjct: 541 CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGS-EPVGCRSDGTCVCKPGFGG 599
Query: 731 PSCE 734
P+CE
Sbjct: 600 PNCE 603
Score = 34.7 bits (78), Expect = 0.75
Identities = 25/90 (27%), Positives = 31/90 (34%), Gaps = 9/90 (10%)
Query: 931 PKTGQCTCRPGVTGQACDRCQLGFFGFSIK-----GCRACRCSPLGAASAQCHENGTCVC 985
P QC C G GQ C C G+ S + C C C GA + G C
Sbjct: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDP---DTGDCYS 433
Query: 986 RPGFEGYKCDRCHDNFFLTA-DGTHCQQCP 1014
+C C F+ D C+ CP
Sbjct: 434 GDENPDIECADCPIGFYNDPHDPRSCKPCP 463
>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
Length = 1193
Score = 565 bits (1456), Expect = e-160
Identities = 278/608 (45%), Positives = 356/608 (58%), Gaps = 27/608 (4%)
Query: 304 CLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPH 363
CL F P AR T+ C+C+G+S +C FDREL R TG+G RC +C D+T G H
Sbjct: 9 CLCFSLLLPAARATSRRE----VCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIH 64
Query: 364 CERCQENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLS 423
CE+C+ FY R C PC+C S GSL +CD++G C+CKP VTG +CDRCLPGFH L+
Sbjct: 65 CEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLT 124
Query: 424 EGGCRP--------CTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPA 475
+ GC C C+PAG CD +GRC CK V G CDRCR G +NL NP
Sbjct: 125 DAGCTQDQRLLDSKCDCDPAGIAGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPE 182
Query: 476 GCSSCFCYGHSKVCASTAQFQVHHILSDFHQGAEGWWARSVGGSEHPPQWSPN--GVLLS 533
GC+ CFCYGHS C S+A++ VH I S FHQ +GW A GS QWS V S
Sbjct: 183 GCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAKLQWSQRHQDVFSS 242
Query: 534 PE--DEEELTAPEKFLGDQRFSYGQPLILTFRVPPGDS-PLPVQLRLEGTGLALSLRHSS 590
+ D AP KFLG+Q+ SYGQ L +RV G P + LEG GL ++
Sbjct: 243 AQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPLMP 302
Query: 591 LSGPQDAGHPREVELRFHLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSPGPSPAGPVF 650
L G + R + + S + +P L F ++RLL NLT+LR+R + G G +
Sbjct: 303 LGKTLPCGLTKTYTFRLN-EHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTG--Y 359
Query: 651 LTEVRLTSARPGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCN 710
+ V L SARP PA WVE C CP GY GQFC+ CA GYKR+ + GP+ +C+PC C
Sbjct: 360 IDNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQ 419
Query: 711 QHGTCDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESR 770
G CDP+TG C C C GFY +P ++ C+PCPC +C+ +PE+
Sbjct: 420 GGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRS--CKPCPCHNGFSCSVMPETE 477
Query: 771 EVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGH 830
EVVC +CPPG G RCE+C DG+FGDP G G +PC CQC+ NVDP+A GNCD L+G
Sbjct: 478 EVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGR 537
Query: 831 CLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCL 890
CL+C+HNT G +C+ C+ G++G LAP PADKC C+C+P G SE + C G C C
Sbjct: 538 CLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG--SEPVGCRS-DGTCVCK 594
Query: 891 PHVTARDC 898
P +C
Sbjct: 595 PGFGGPNC 602
Score = 202 bits (515), Expect = 2e-51
Identities = 211/844 (25%), Positives = 342/844 (40%), Gaps = 84/844 (9%)
Query: 777 CPPGQRGRRCEVCDDGFFGDP--LGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRC 834
CP G +G+ C+ C G+ D LG FG C C C G G CDP +G C
Sbjct: 384 CPVGYKGQFCQDCASGYKRDSARLGPFG---TCIPCNCQGG------GACDPDTGDCYSG 434
Query: 835 LHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVT 894
N + C C GFY PR C PC CH S S + V +C P VT
Sbjct: 435 DENPDIE-CADCPIGFYNDPHDPR---SCKPCPCHNGFSCSVMPETEEVVCN-NCPPGVT 489
Query: 895 ARDCSRCYPGFF-----DLQPGRGCRSCKCHPL--GSQEDQCHPKTGQCT-CRPGVTGQA 946
C C G+F + P R C+ C+C+ S C TG+C C G
Sbjct: 490 GARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIY 549
Query: 947 CDRCQLGFFGFSIKG-----CRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNF 1001
CD+C+ G+FG + CRAC C+P+G+ C +GTCVC+PGF G C+ H F
Sbjct: 550 CDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCE--HGAF 607
Query: 1002 FLTADGTHCQQCPSCYALVKEEAAKLKARLTLTEGWL---QGSDCGSPWGPLDILLGEAP 1058
CP+CY VK + + +L E + QG D P L+ + +A
Sbjct: 608 ----------SCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAE 657
Query: 1059 RG--DVYQGHHLLPGAREAFLEQMMSLEGAVKAAREQLQRLNKGARCAQAGSQKTCTQLA 1116
+ D+ + + GA + Q+ + + + +L L +A + ++
Sbjct: 658 QALQDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVR 717
Query: 1117 DLEAVLESSEEEILHAAAILASLEIP-QEGPSQPTKWSHLATEARALARSHRDTATKIAA 1175
D ++ + + + A L + IP + P + LA EA LA SH ++A+ +
Sbjct: 718 DTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQ 777
Query: 1176 TAWRALLASNTSYALLWNLL-----------EGRVALETQRDLEDRYQEVQAAQKALRTA 1224
S + +L+ L +G V LE Q + A
Sbjct: 778 LTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQA 837
Query: 1225 VAEVLPEAESVLATVQQVGADTAPYLALLASPGALPQKSRAEDLGL-------KAKALEK 1277
E + L + V A K +A+ L + K +K
Sbjct: 838 EIEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQK 897
Query: 1278 TVASWQHMATEAARTLQTAAQATLRQTEPLTKLHQEARAALTQASSSVQAATVTVMGART 1337
+ +W+ EA + LQ + + L++ A A ++A ++ T +
Sbjct: 898 NLGNWKE---EAQQLLQNGKSGREKSDQLLSR----ANLAKSRAQEALSMGNATFYEVES 950
Query: 1338 LLADLEGMKLQFPRPKDQAALQRKADSVSDRLLADTRKKTKQAERMLGNAAPLSSSAKKK 1397
+L +L LQ K +A K S + ++D KT+QAER LG+AA + AK
Sbjct: 951 ILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNG 1010
Query: 1398 GREAEVLAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQASQQVLASEARRQELE-- 1455
EA ++ + + +L E A + + A+L+ ++V E R+ELE
Sbjct: 1011 AGEALEISSEIEQEIGSLNLEANVTADGALAM-EKGLASLKSEMREV-EGELERKELEFD 1068
Query: 1456 ----EAERVGAGLSEMEQQIRESRISLEKDIETLSELLARLGSLDTHQAPAQALNETQWA 1511
+ V +++ + + + ++++ + TL LL + + L E +
Sbjct: 1069 TNMDAVQMVITEAQKVDTRAKNAGVTIQDTLNTLDGLLHLMDQPLSVDEEGLVLLEQK-- 1126
Query: 1512 LERLRLQLGSPGSLQRKLSLLEQESQQQELQIQGFESDLAEIRADKQNLEAILHSLPENC 1571
L R + Q+ S L+ +S LE+ ++QQ + E+ + I AD +NLE I +LP C
Sbjct: 1127 LSRAKTQINS--QLRPMMSELEERARQQRGHLHLLETSIDGILADVKNLENIRDNLPPGC 1184
Query: 1572 ASWQ 1575
+ Q
Sbjct: 1185 YNTQ 1188
Score = 115 bits (288), Expect = 3e-25
Identities = 62/148 (41%), Positives = 80/148 (54%), Gaps = 22/148 (14%)
Query: 831 CLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCL 890
CL C NT G HCE C+ GFY R D+C+PC+C+ +GS+S + CD +G+CSC
Sbjct: 53 CLNCNDNTDGIHCEKCKNGFYRH----RERDRCLPCNCNSKGSLSAR--CDN-SGRCSCK 105
Query: 891 PHVTARDCSRCYPGFFDLQPGRGC--------RSCKCHPLGSQEDQCHPKTGQCTCRPGV 942
P VT C RC PGF L GC C C P G C G+C C+P V
Sbjct: 106 PGVTGARCDRCLPGFHMLTDA-GCTQDQRLLDSKCDCDPAGI-AGPC--DAGRCVCKPAV 161
Query: 943 TGQACDRCQLGFF---GFSIKGCRACRC 967
TG+ CDRC+ G++ G + +GC C C
Sbjct: 162 TGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 94.7 bits (234), Expect = 6e-19
Identities = 53/177 (29%), Positives = 78/177 (44%), Gaps = 22/177 (12%)
Query: 888 SCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQAC 947
+C + C +C GF+ + C C C+ GS +C +G+C+C+PGVTG C
Sbjct: 55 NCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCD-NSGRCSCKPGVTGARC 113
Query: 948 DRCQLGFFGFSIKGC--------RACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHD 999
DRC GF + GC C C P G A C + G CVC+P G +CDRC
Sbjct: 114 DRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIA-GPC-DAGRCVCKPAVTGERCDRCRS 171
Query: 1000 NFFLTADGTHCQQCPSCYALVKEEAAKLKARLTL----------TEGWLQGSDCGSP 1046
++ DG + + C C+ + + A ++ +GW GSP
Sbjct: 172 GYY-NLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSP 227
Score = 74.3 bits (181), Expect = 9e-13
Identities = 49/152 (32%), Positives = 63/152 (41%), Gaps = 19/152 (12%)
Query: 774 CTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLR 833
C +C G CE C +GF+ C C C+ +A CD SG C
Sbjct: 53 CLNCNDNTDGIHCEKCKNGFYRHR-----ERDRCLPCNCNSKGSLSA--RCDN-SGRC-S 103
Query: 834 CLHNTTGDHCEHCQEGFYGSALAPRPADKCM---PCSCHPQGSVSEQMPCDPVTGQCSCL 890
C TG C+ C GF+ A D+ + C C P G PCD G+C C
Sbjct: 104 CKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAG---PCD--AGRCVCK 158
Query: 891 PHVTARDCSRCYPGFFDLQPG--RGCRSCKCH 920
P VT C RC G+++L G GC C C+
Sbjct: 159 PAVTGERCDRCRSGYYNLDGGNPEGCTQCFCY 190
Score = 73.2 bits (178), Expect = 2e-12
Identities = 45/149 (30%), Positives = 63/149 (42%), Gaps = 13/149 (8%)
Query: 271 CKC-NGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC 329
C C NG + P+ + C TG CE C + P+ G C PC C
Sbjct: 462 CPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPF--GEHGPVRPCQPCQC 519
Query: 330 SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP-----CQPCD 384
+ + R TG RC C +TAG +C++C+ ++ DP P C+ C+
Sbjct: 520 NNNVDPSA-SGNCDRLTG---RCLKCIHNTAGIYCDQCKAGYFG-DPLAPNPADKCRACN 574
Query: 385 CQSAGSLHLQCDDTGTCACKPTVTGWKCD 413
C GS + C GTC CKP G C+
Sbjct: 575 CNPMGSEPVGCRSDGTCVCKPGFGGPNCE 603
Score = 72.8 bits (177), Expect = 2e-12
Identities = 65/254 (25%), Positives = 83/254 (32%), Gaps = 41/254 (16%)
Query: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
C C G + C PD C +C C F + P C PC C
Sbjct: 416 CNCQGGGA-CDPDTGD---CYSGDENPDIECADCPIGFYNDP------HDPRSCKPCPCH 465
Query: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFY-----HWDPRMPCQPCDC 385
C+ E C++C G CE C + ++ P PCQPC C
Sbjct: 466 N-GFSCSVMPETEEVV-----CNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQC 519
Query: 386 QSA--GSLHLQCDD-TGTCA-CKPTVTGWKCDRCLPGFHS-----LSEGGCRPCTCNPAG 436
+ S CD TG C C G CD+C G+ CR C CNP G
Sbjct: 520 NNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMG 579
Query: 437 SLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVCASTAQFQ 496
S G C CK G C+ H C +C+ ++ Q Q
Sbjct: 580 SEPVGCRSDGTCVCKPGFGGPNCE-----------HGAFSCPACYNQVKIQMDQFMQQLQ 628
Query: 497 VHHILSDFHQGAEG 510
L QG +G
Sbjct: 629 RMEALISKAQGGDG 642
Score = 64.3 bits (155), Expect = 9e-10
Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 8/98 (8%)
Query: 917 CKCHPLGSQ---EDQCHPKTGQ----CTCRPGVTGQACDRCQLGFFGFSIKG-CRACRCS 968
C C+ Q + + H +TG C G C++C+ GF+ + C C C+
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCN 87
Query: 969 PLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTAD 1006
G+ SA+C +G C C+PG G +CDRC F + D
Sbjct: 88 SKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTD 125
Score = 49.3 bits (116), Expect = 3e-05
Identities = 36/120 (30%), Positives = 49/120 (40%), Gaps = 19/120 (15%)
Query: 271 CKCNGHAS-ECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC 329
C CN S D +G+ C C+ TG C+RCLP F A T + C+C
Sbjct: 84 CNCNSKGSLSARCDNSGR--CSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDC 141
Query: 330 --SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--CQPCDC 385
+G + C GRC C+ G C+RC+ +Y+ D P C C C
Sbjct: 142 DPAGIAGPC-----------DAGRC-VCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 40.4 bits (93), Expect = 0.014
Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 5/64 (7%)
Query: 675 CPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGTCDP----NTGICVCSHHTEG 730
C G +C+ C GY + P C C CN G+ +P + G CVC G
Sbjct: 541 CIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGS-EPVGCRSDGTCVCKPGFGG 599
Query: 731 PSCE 734
P+CE
Sbjct: 600 PNCE 603
Score = 34.7 bits (78), Expect = 0.75
Identities = 25/90 (27%), Positives = 31/90 (34%), Gaps = 9/90 (10%)
Query: 931 PKTGQCTCRPGVTGQACDRCQLGFFGFSIK-----GCRACRCSPLGAASAQCHENGTCVC 985
P QC C G GQ C C G+ S + C C C GA + G C
Sbjct: 377 PWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGACDP---DTGDCYS 433
Query: 986 RPGFEGYKCDRCHDNFFLTA-DGTHCQQCP 1014
+C C F+ D C+ CP
Sbjct: 434 GDENPDIECADCPIGFYNDPHDPRSCKPCP 463
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 475 bits (1222), Expect = e-133
Identities = 395/1306 (30%), Positives = 540/1306 (41%), Gaps = 160/1306 (12%)
Query: 290 CRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGR-SEECTFDRELFRSTGH 348
C C + G DC RC + P C PC+C R +E T
Sbjct: 1457 CPCHAHVIGRDCSRCATGYWGFP----------NCRPCDCGARLCDELT----------- 1495
Query: 349 GGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGSLHLQ---CD-DTGTCACK 404
G+C C T P C CQ + P + C+ C+C G L CD D+G C C+
Sbjct: 1496 -GQCI-CPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCR 1553
Query: 405 PTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD-TCDPRSGRCPCKENVEGNLCDRCR 463
P VTG +CD C PGFH CRPC C+ AG+ CDP +G+C CKENV+G CD+C
Sbjct: 1554 PNVTGRRCDTCSPGFHGYPR--CRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCS 1611
Query: 464 PGTFNLQPHNPAGCSSCFCYGHSKVCASTAQFQVHHILSDFHQGAEGWWARSVGGSEHPP 523
GTF+L NP GC+ CFC+G ++ C S++ + + EGW S P
Sbjct: 1612 LGTFSLDAANPKGCTRCFCFGATERCRSSSYTRQEFV------DMEGWVLLSTDRQVVPH 1665
Query: 524 QWSPNGVLLS----------PEDEEEL--TAPEKFLGDQRFSYGQPLI--LTFRVPPGDS 569
+ P +L PE EL AP +LGD+ SYG L L GD
Sbjct: 1666 ERQPGTEMLRADLRHVPEAVPEAFPELYWQAPPSYLGDRVSSYGGTLRYELHSETQRGDV 1725
Query: 570 PLPVQLR----LEGTGLALSLRHSSLSGPQDA--GHPREVELRFHLQETSEDVAPPLPPF 623
+P++ R L+G ++++ + P G + VE F ET V+
Sbjct: 1726 FVPMESRPDVVLQGNQMSITFLEPAYPTPGHVHRGQLQLVEGNFRHTETRNTVSRE---- 1781
Query: 624 HFQRLLANLTSLRLRVSPGPSPAGPVFLTEVRLTSARP-GLSPPASWVEICSCPTGYTGQ 682
+LA+L L++R + VFL V L A P G AS VE+C CP Y G
Sbjct: 1782 ELMMVLASLEQLQIRALFSQISSA-VFLRRVALEVASPAGQGALASNVELCLCPASYRGD 1840
Query: 683 FCESCAPGYKREMPQGGPYASCVPCTCNQHGT-CDPNTGICV-CSHHTEGPSCERCLPGF 740
C+ CAPG+ R++ +G CVPC C+ H C P +G+CV C H+TEG CERC GF
Sbjct: 1841 SCQECAPGFYRDV-KGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGF 1899
Query: 741 YGNPFAGQADDCQPCPCPGQSACTTIPES-----REVVCTHCPPGQRGRRCEVCDDGFFG 795
+ A C CPCP E C C PG G CE C GFFG
Sbjct: 1900 VSSRDDPSAP-CVSCPCPLSVPSNNFAEGCVLRGGRTQCL-CKPGYAGASCERCAPGFFG 1957
Query: 796 DPLGLFGHPQPCHQCQCSGNVDPNAV-GNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSA 854
+PL L QPC CSGN DPN + +CDPL+G C CL +TTG CE C GFYG+A
Sbjct: 1958 NPLVLGSSCQPC---DCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNA 2014
Query: 855 LAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGC 914
L P C C C P G+ + CDP +G C C VT R C RC G F GC
Sbjct: 2015 LLP---GNCTRCDCTPCGTEA----CDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGC 2067
Query: 915 RSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAAS 974
R C C P ++ +CHP++GQC CRPG G C C G++G +GCR C+C P G
Sbjct: 2068 RPCACGP-AAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQC-PGGRCD 2125
Query: 975 AQCHENGTCVCRPGFEGYKCDRCHDNFFLTADG------THCQQCPSCYALVKEEAAKLK 1028
G C C PG G +CD C + G HC+ C C L+ ++ +
Sbjct: 2126 PH---TGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHCVVLLLDDLERAG 2182
Query: 1029 ARLTLTEGWLQGSDCGS-PWGPLDILLGE------------APRGDVYQGHHLLPGAREA 1075
A L L+G + S W L L PR + Q +L +
Sbjct: 2183 ALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLRSPLGPRHETAQQLEVLEQQSTS 2242
Query: 1076 FLEQMMSLEGAVKAAREQLQRLNKGARCAQAGSQKTCTQLADLEAVLESSEEEILHAAAI 1135
+ L G R+Q +L G ++ + ++ L + H
Sbjct: 2243 LGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLAAIRAVDRTLSELMSQTGHLGLA 2302
Query: 1136 LASLEIPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRALLASNTSYALLWNLL 1195
AS ++ + L E RA A + A + LLA L +L
Sbjct: 2303 NASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAEAELAAAQRLLARVQEQ--LSSLW 2360
Query: 1196 EGRVALETQRDLEDRYQEVQAAQKALRTAVAEVLPEA--------------ESVLATVQQ 1241
E AL TQ DR + +A LR A+ + E L Q+
Sbjct: 2361 EENQALATQT--RDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEALQRKQE 2418
Query: 1242 VGADTAPYLALL-ASPGALPQKSRA-EDLGLKAKALEKTVASWQHMATEAARTLQTAAQA 1299
+ D A A L A+ L R L + LE+ AS T + +QT + A
Sbjct: 2419 LSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFSPA 2478
Query: 1300 --TLRQTEPLTKLHQEA---------------RAALTQASSSVQAATVTVMGARTLLADL 1342
LR E Q+ + LTQ + A ++ A D
Sbjct: 2479 GSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDA 2538
Query: 1343 EGMKLQFPRPKDQAALQRKADSVSDRLLADT---RKKTKQAERMLGNA-APLSSS----- 1393
G LQ +++ + +LLA++ + Q ++ LG A L +
Sbjct: 2539 AGQALQQADHTWATVVRQGLVDRAQQLLANSTALEEAMLQEQQRLGLVWAALQGARTQLR 2598
Query: 1394 ---AKKKGREAEVLAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQASQQVLASEAR 1450
AKK EA + A + +K AH +A +Q AT Q+ Q +
Sbjct: 2599 DVRAKKDQLEAHIQAAQAMLAMDTDETSKKIAHAKAVAAEAQDTATRVQSQLQAMQENVE 2658
Query: 1451 RQELEEAERVGAGLSEMEQQIRESRISLEKDIETLSELLARLGSLD 1496
R + + G L + S +LEK TL +LLA+L L+
Sbjct: 2659 RWQGQYEGLRGQDLGQAVLDAGHSVSTLEK---TLPQLLAKLSILE 2701
Score = 297 bits (760), Expect = 6e-80
Identities = 188/543 (34%), Positives = 255/543 (46%), Gaps = 82/543 (15%)
Query: 3 AAALLLGLALLAPRAAGAGMGACYDGAGRPQRCLPVFENAAFGRLAQASHTCGS------ 56
A LL+GLALL G + AG P + N A G AS TCG
Sbjct: 20 APLLLVGLALL-------GAARAREEAGGGFSLHPPYFNLAEGARIAASATCGEEAPARG 72
Query: 57 ---PPED-FCPHVGAAGAGA---------HCQRCDAADPQRHHNASYLTDFHSQDESTWW 103
P ED +C VG AG +C C AA+ + H AS D WW
Sbjct: 73 SPRPTEDLYCKLVGGPVAGGDPNQTIRGQYCDICTAANSNKAHPASNAID----GTERWW 128
Query: 104 QSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKFHTS-RPESFAIYKRSRADGPWEPYQF 162
QSP ++ G++Y VN+TL LG+ + + YV +KF S RP+ + + + ++P+QF
Sbjct: 129 QSPPLSRGLEY-NEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQF 187
Query: 163 YSASCQKTYGRPEGQYLRPGEDERVAFCTSEFSDISPLSGGNVAFSTLEGRPSAYNFEES 222
+++S + R Q L + A CT+E+S I PL G + S + GRP A NF S
Sbjct: 188 FASSKRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPGAMNFSYS 247
Query: 223 PGLQEWVTSTELLISLDRLNTFGDDIF----KDPKVLQSYYYAVSDFSVGGRCKCNGHAS 278
P L+E+ +T + + R NT + +DP V + YYY++ D S+GGRC C+GHA
Sbjct: 248 PLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHAD 307
Query: 279 ECG---PDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEE 335
C P +L C CQHNT G C+RC P F +PW TA +A+EC CNC G + +
Sbjct: 308 ACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATD 367
Query: 336 CTFDRELFRSTGH---------GGRCHHCRDHTAGPHCERCQENFYHWDPRMP------C 380
C +D E+ R GG C C+ HT G +CERC FY P P C
Sbjct: 368 CYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYR-SPNHPLDSPHVC 426
Query: 381 QPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCN------- 433
+ C+C+S + D TG C C+P +G +CD C GF P + N
Sbjct: 427 RRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVL 486
Query: 434 PAGSLDTC--------------DPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSS 479
PAG + C DPR GRC CK N +G C+ C PG + GC
Sbjct: 487 PAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG------PGCQP 540
Query: 480 CFC 482
C C
Sbjct: 541 CQC 543
Score = 208 bits (529), Expect = 4e-53
Identities = 133/404 (32%), Positives = 166/404 (41%), Gaps = 64/404 (15%)
Query: 673 CSCPTGYTGQFCESCAPGYKRE--MPQGGPYAS-CVPCTCNQHGT---CDPNT------- 719
C+C G C+ C PG+ ++ P A+ C C C H T DP
Sbjct: 322 CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQ 381
Query: 720 ---------GICV-CSHHTEGPSCERCLPGFYGNPF--AGQADDCQPCPCPGQSACTTIP 767
G+C+ C HHT G +CERCLPGFY +P C+ C C T
Sbjct: 382 SLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTC- 440
Query: 768 ESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCH---------------QCQC 812
E C +C P G RC+VC +GF G P +P P C C
Sbjct: 441 EDLTGRC-YCRPNFSGERCDVCAEGFTGFP---SCYPTPSSSNDTREQVLPAGQIVNCDC 496
Query: 813 SGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQG 872
S DP G CL C N G HCE C GFYG C PC C G
Sbjct: 497 SAAGTQGNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYGPG--------CQPCQCSSPG 547
Query: 873 SVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPK 932
++ CDP TGQC C C RC PG+F C+ C C P G+ + C +
Sbjct: 548 VADDR--CDPDTGQCRCRVGFEGATCDRCAPGYFHFPL---CQLCGCSPAGTLPEGC-DE 601
Query: 933 TGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENGTCVCRPGFEGY 992
G+C C+P G CDRC+ G+ GF C+AC C P GA C G C CRPG+ G
Sbjct: 602 AGRCLCQPEFAGPHCDRCRPGYHGF--PNCQACTCDPRGALDQLCGAGGLCRCRPGYTGT 659
Query: 993 KCDRCHDNF--FLTADGTHCQQCPSCYALVKEEAAKLKARLTLT 1034
C C F F + HC S +A + + R +T
Sbjct: 660 ACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVT 703
Score = 207 bits (526), Expect = 8e-53
Identities = 119/346 (34%), Positives = 155/346 (44%), Gaps = 52/346 (15%)
Query: 707 CTCNQHGTC-------DPNTGICVCSHHTEGPSCERCLPGFYGNPF----AGQADDCQPC 755
C C+ H DP C C H+T G +C+RC PGF P+ A A++CQ C
Sbjct: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSC 359
Query: 756 PCPGQSA-CTTIPE------SREV--------VCTHCPPGQRGRRCEVCDDGFFGDPLGL 800
C G + C PE S+ + VC C G CE C GF+ P
Sbjct: 360 NCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHP 419
Query: 801 FGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYG-------- 852
P C +C C + G C+ L+G C C N +G+ C+ C EGF G
Sbjct: 420 LDSPHVCRRCNCESDFTD---GTCEDLTGRCY-CRPNFSGERCDVCAEGFTGFPSCYPTP 475
Query: 853 -SALAPR----PADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFD 907
S+ R PA + + C C G+ DP G+C C P+ C C PGF+
Sbjct: 476 SSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFY- 534
Query: 908 LQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRC 967
G GC+ C+C G +D+C P TGQC CR G G CDRC G+F F + C+ C C
Sbjct: 535 ---GPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL--CQLCGC 589
Query: 968 SPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQC 1013
SP G C E G C+C+P F G CDRC + +CQ C
Sbjct: 590 SPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYH---GFPNCQAC 632
Score = 200 bits (508), Expect = 1e-50
Identities = 122/338 (36%), Positives = 146/338 (43%), Gaps = 54/338 (15%)
Query: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 728
C C G+ G C+ CAPGY + C C C+ GT CD G C+C
Sbjct: 560 CRCRVGFEGATCDRCAPGYFH-------FPLCQLCGCSPAGTLPEGCD-EAGRCLCQPEF 611
Query: 729 EGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEV 788
GP C+RC PG++G P +CQ C C + A + + + C PG G C+
Sbjct: 612 AGPHCDRCRPGYHGFP------NCQACTCDPRGALDQLCGAGGLC--RCRPGYTGTACQE 663
Query: 789 CDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQE 848
C GF G P C C CS +A CDP SG C C TG C+ C
Sbjct: 664 CSPGFHGFP--------SCVPCHCSAEGSLHAA--CDPRSGQC-SCRPRVTGLRCDTCVP 712
Query: 849 GFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQ----CSCLPHVTARDCSRCYPG 904
G Y C SCHP G P DP + C C HV C RC PG
Sbjct: 713 GAYNFPY-------CEAGSCHPAGLA----PVDPALPEAQVPCMCRAHVEGPSCDRCKPG 761
Query: 905 FFDLQPGR--GCRSCKCHPLGSQED--QCHPKTGQCTCRPGVTGQACDRCQLGFFGF--- 957
F+ L P GC C C G+ +C P TGQC C+P V GQAC C+ GFFG
Sbjct: 762 FWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQA 821
Query: 958 SIKGCRACRCSPLGAASAQCH-ENGTCVCRPGFEGYKC 994
GCR+CRC GA C G C CRP +G C
Sbjct: 822 DYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTC 859
Score = 194 bits (493), Expect = 6e-49
Identities = 132/391 (33%), Positives = 167/391 (42%), Gaps = 60/391 (15%)
Query: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 728
C C + G CE CAPG+ GP C PC C+ G CDP+TG C C
Sbjct: 515 CLCKPNFQGTHCELCAPGFY------GP--GCQPCQCSSPGVADDRCDPDTGQCRCRVGF 566
Query: 729 EGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPES-REVVCTHCPPGQRGRRCE 787
EG +C+RC PG++ P CQ C C S T+PE E C P G C+
Sbjct: 567 EGATCDRCAPGYFHFPL------CQLCGC---SPAGTLPEGCDEAGRCLCQPEFAGPHCD 617
Query: 788 VCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPL--SGHCLRCLHNTTGDHCEH 845
C G+ G P C C C DP G D L +G RC TG C+
Sbjct: 618 RCRPGYHGFP--------NCQACTC----DPR--GALDQLCGAGGLCRCRPGYTGTACQE 663
Query: 846 CQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGF 905
C GF+G C+PC C +GS+ CDP +GQCSC P VT C C PG
Sbjct: 664 CSPGFHGFP-------SCVPCHCSAEGSL--HAACDPRSGQCSCRPRVTGLRCDTCVPGA 714
Query: 906 FDLQPGRGCRSCKCHPLG-SQEDQCHPKTG-QCTCRPGVTGQACDRCQLGFFGFSI---K 960
++ C + CHP G + D P+ C CR V G +CDRC+ GF+G S +
Sbjct: 715 YNFPY---CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPE 771
Query: 961 GCRACRCSPLGAAS--AQCHEN-GTCVCRPGFEGYKCDRCHDNFF--LTADGTHCQQCPS 1015
GC C C G A+C G C C+P G C C D FF AD C+ C
Sbjct: 772 GCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRC 831
Query: 1016 CYALVKEEAAKLKARLTLTEGWLQGSDCGSP 1046
++ + + + QG C P
Sbjct: 832 DIGGALGQSCEPRTGVCRCRPNTQGPTCSEP 862
Score = 177 bits (448), Expect = 9e-44
Identities = 116/356 (32%), Positives = 148/356 (41%), Gaps = 65/356 (18%)
Query: 673 CSCPTGYTGQFCESCAPGY-------------KREMPQGGPYASCVPCTCNQHGT----C 715
C C ++G+ C+ CA G+ Q P V C C+ GT C
Sbjct: 447 CYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNAC 506
Query: 716 --DPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPC--PGQSACTTIPESRE 771
DP G C+C + +G CE C PGFYG CQPC C PG + P++ +
Sbjct: 507 RKDPRVGRCLCKPNFQGTHCELCAPGFYG-------PGCQPCQCSSPGVADDRCDPDTGQ 559
Query: 772 VVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCS--GNVDPNAVGNCDPLSG 829
C G G C+ C G+F PL C C CS G + CD +G
Sbjct: 560 C---RCRVGFEGATCDRCAPGYFHFPL--------CQLCGCSPAGTLPEG----CDE-AG 603
Query: 830 HCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSC 889
CL C G HC+ C+ G++G C C+C P+G++ + G C C
Sbjct: 604 RCL-CQPEFAGPHCDRCRPGYHGFP-------NCQACTCDPRGALDQLCGAG---GLCRC 652
Query: 890 LPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDR 949
P T C C PGF C C C GS C P++GQC+CRP VTG CD
Sbjct: 653 RPGYTGTACQECSPGFHGFP---SCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDT 709
Query: 950 CQLGFFGFSIKGCRACRCSPLGAA---SAQCHENGTCVCRPGFEGYKCDRCHDNFF 1002
C G + F C A C P G A A C+CR EG CDRC F+
Sbjct: 710 CVPGAYNFPY--CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFW 763
Score = 138 bits (348), Expect = 4e-32
Identities = 77/203 (37%), Positives = 93/203 (45%), Gaps = 18/203 (8%)
Query: 286 GQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRS 345
G+ C C+ G CERC P F P G++ C PC+CSG + +
Sbjct: 1933 GRTQCLCKPGYAGASCERCAPGFFGNPLVLGSS-----CQPCDCSGNGDPNLLFSDCDPL 1987
Query: 346 TGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--CQPCDCQSAGSLHLQCD-DTGTCA 402
T G C C HT GP CE C FY + +P C CDC G+ CD +G C
Sbjct: 1988 T---GACRGCLRHTTGPRCEICAPGFY-GNALLPGNCTRCDCTPCGT--EACDPHSGHCL 2041
Query: 403 CKPTVTGWKCDRCLPGFHSLSE-GGCRPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDR 461
CK VTG +CDRC G GGCRPC C PA C P+SG+C C+ G C
Sbjct: 2042 CKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRE 2101
Query: 462 CRPGTFNLQPHNPAGCSSCFCYG 484
C PG + L GC C C G
Sbjct: 2102 CAPGYWGLPEQ---GCRRCQCPG 2121
Score = 135 bits (340), Expect = 3e-31
Identities = 77/207 (37%), Positives = 99/207 (47%), Gaps = 31/207 (14%)
Query: 281 GPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDR 340
G D AG+ C CQ G C+RC P + P C C C R
Sbjct: 598 GCDEAGR--CLCQPEFAGPHCDRCRPGYHGFP----------NCQACTCDPRGA------ 639
Query: 341 ELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGSLHLQCDD-TG 399
L + G GG C CR G C+ C F+ + C PC C + GSLH CD +G
Sbjct: 640 -LDQLCGAGGLCR-CRPGYTGTACQECSPGFHGFPS---CVPCHCSAEGSLHAACDPRSG 694
Query: 400 TCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSGR----CPCKENVE 455
C+C+P VTG +CD C+PG ++ C +C+PAG L DP C C+ +VE
Sbjct: 695 QCSCRPRVTGLRCDTCVPGAYNFPY--CEAGSCHPAG-LAPVDPALPEAQVPCMCRAHVE 751
Query: 456 GNLCDRCRPGTFNLQPHNPAGCSSCFC 482
G CDRC+PG + L P NP GC+ C C
Sbjct: 752 GPSCDRCKPGFWGLSPSNPEGCTRCSC 778
Score = 129 bits (325), Expect = 2e-29
Identities = 77/234 (32%), Positives = 106/234 (45%), Gaps = 28/234 (11%)
Query: 672 ICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQ----HGTCDPNTGICVCSHH 727
+C C GYTG C+ C+PG+ + SCVPC C+ H CDP +G C C
Sbjct: 649 LCRCRPGYTGTACQECSPGFH-------GFPSCVPCHCSAEGSLHAACDPRSGQCSCRPR 701
Query: 728 TEGPSCERCLPGFYGNPFAGQADDCQPCP-CPGQSACTTIPESREVVCTHCPPGQRGRRC 786
G C+ C+PG Y P+ +A C P P A +PE+ +V C C G C
Sbjct: 702 VTGLRCDTCVPGAYNFPYC-EAGSCHPAGLAPVDPA---LPEA-QVPCM-CRAHVEGPSC 755
Query: 787 EVCDDGFFG-DPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEH 845
+ C GF+G P +P+ C +C C V C P +G C C + G C
Sbjct: 756 DRCKPGFWGLSP----SNPEGCTRCSCDLRGTLGGVAECQPGTGQCF-CKPHVCGQACAS 810
Query: 846 CQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCS 899
C++GF+G L C C C G++ + C+P TG C C P+ CS
Sbjct: 811 CKDGFFG--LDQADYFGCRSCRCDIGGALGQS--CEPRTGVCRCRPNTQGPTCS 860
Score = 124 bits (311), Expect = 7e-28
Identities = 77/222 (34%), Positives = 97/222 (43%), Gaps = 36/222 (16%)
Query: 706 PCTCNQHG----TCDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQS 761
PC C++ G TC+P G C C H G C RC G++G P +C+PC C G
Sbjct: 1437 PCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFP------NCRPCDC-GAR 1489
Query: 762 ACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHP-QPCHQCQCSG-NVDPN 819
C + C CPP C +C FG HP C +C CSG +
Sbjct: 1490 LCDELTGQ----CI-CPPRTIPPDCLLCQPQTFG------CHPLVGCEECNCSGPGIQEL 1538
Query: 820 AVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMP 879
CD SG C +C N TG C+ C GF+G +C PC CH G+
Sbjct: 1539 TDPTCDTDSGQC-KCRPNVTGRRCDTCSPGFHG-------YPRCRPCDCHEAGTAPG--V 1588
Query: 880 CDPVTGQCSCLPHVTARDCSRCYPGFFDLQPG--RGCRSCKC 919
CDP+TGQC C +V C +C G F L +GC C C
Sbjct: 1589 CDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
Score = 122 bits (307), Expect = 2e-27
Identities = 74/229 (32%), Positives = 93/229 (40%), Gaps = 42/229 (18%)
Query: 271 CKCN-----GHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECL 325
C C+ G+A P V C C+ N GT CE C P F C
Sbjct: 494 CDCSAAGTQGNACRKDPRVG---RCLCKPNFQGTHCELCAPGFY-----------GPGCQ 539
Query: 326 PCNCSG---RSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQP 382
PC CS + C D G+C CR G C+RC ++H+ CQ
Sbjct: 540 PCQCSSPGVADDRCDPDT---------GQCR-CRVGFEGATCDRCAPGYFHFPL---CQL 586
Query: 383 CDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCD 442
C C AG+L CD+ G C C+P G CDRC PG+H C+ CTC+P G+LD
Sbjct: 587 CGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGFP--NCQACTCDPRGALDQLC 644
Query: 443 PRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVCAS 491
G C C+ G C C PG H C C C + A+
Sbjct: 645 GAGGLCRCRPGYTGTACQECSPGF-----HGFPSCVPCHCSAEGSLHAA 688
Score = 111 bits (277), Expect = 6e-24
Identities = 68/223 (30%), Positives = 84/223 (37%), Gaps = 54/223 (24%)
Query: 865 PCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGF------------------- 905
PC CH G+ C+P GQC C HV RDCSRC G+
Sbjct: 1437 PCGCHEVGATGPT--CEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDEL 1494
Query: 906 ----------------------FDLQPGRGCRSCKCHPLGSQE---DQCHPKTGQCTCRP 940
F P GC C C G QE C +GQC CRP
Sbjct: 1495 TGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRP 1554
Query: 941 GVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDRCHD 999
VTG+ CD C GF G+ CR C C G A C G C C+ +G KCD+C
Sbjct: 1555 NVTGRRCDTCSPGFHGY--PRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSL 1612
Query: 1000 NFFLTADGTHCQQCPSCYALVKEEAAK----LKARLTLTEGWL 1038
F + D + + C C+ E + + EGW+
Sbjct: 1613 GTF-SLDAANPKGCTRCFCFGATERCRSSSYTRQEFVDMEGWV 1654
Score = 67.0 bits (162), Expect = 1e-10
Identities = 35/102 (34%), Positives = 44/102 (43%), Gaps = 8/102 (7%)
Query: 913 GCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGA 972
G R C CH +G+ C P GQC C V G+ C RC G++GF CR C C
Sbjct: 1434 GARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGF--PNCRPCDC----- 1486
Query: 973 ASAQCHE-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQC 1013
+ C E G C+C P C C F C++C
Sbjct: 1487 GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEEC 1528
Score = 56.6 bits (135), Expect = 2e-07
Identities = 38/97 (39%), Positives = 44/97 (45%), Gaps = 21/97 (21%)
Query: 405 PTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSG------RCPCKENVEGNL 458
PTVT R +S GG C C+ G D CD + +C C+ N G
Sbjct: 281 PTVTR----RYYYSIKDISIGG--RCVCH--GHADACDAKDPTDPFRLQCTCQHNTCGGT 332
Query: 459 CDRCRPGTFNLQPHNPAG------CSSCFCYGHSKVC 489
CDRC PG FN QP PA C SC CYGH+ C
Sbjct: 333 CDRCCPG-FNQQPWKPATANSANECQSCNCYGHATDC 368
Score = 52.8 bits (125), Expect = 3e-06
Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
Query: 405 PTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD-TCDPRSGRCPCKENVEGNLCDRCR 463
P+ + C G RPC C+ G+ TC+P G+CPC +V G C RC
Sbjct: 1413 PSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCA 1472
Query: 464 PGTFNLQPHNPAGCSSCFC 482
G + P C + C
Sbjct: 1473 TGYWGFPNCRPCDCGARLC 1491
Score = 32.7 bits (73), Expect = 2.8
Identities = 22/85 (25%), Positives = 30/85 (35%), Gaps = 5/85 (5%)
Query: 940 PGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDRCH 998
P + C F G R C C +GA C G C C G C RC
Sbjct: 1413 PSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCA 1472
Query: 999 DNFFLTADGTHCQQCPSCYALVKEE 1023
++ +C+ C C A + +E
Sbjct: 1473 TGYW---GFPNCRPC-DCGARLCDE 1493
>gi|148613884 netrin 1 [Homo sapiens]
Length = 604
Score = 384 bits (987), Expect = e-106
Identities = 194/433 (44%), Positives = 265/433 (61%), Gaps = 19/433 (4%)
Query: 9 GLALLAPRAAGAGMGACYDGAGRPQRCLPVFENAAFGRLAQASHTCGSPPEDFCPHVGAA 68
GL++ A +AA C D G P+RC+P F NAAFG+ + S TCG PP +C V
Sbjct: 27 GLSMFAGQAAQPD--PCSDENGHPRRCIPDFVNAAFGKDVRVSSTCGRPPARYCV-VSER 83
Query: 69 GAGA--HCQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGK 126
G C C+A+DP++ H ++LTD ++ T WQS + +Q+P +V +TL LGK
Sbjct: 84 GEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENY---LQFPHNVTLTLSLGK 140
Query: 127 AYEITYVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPGEDER 186
+E+TYV L+F + RPES AIYK W P+QFYS C+K Y RP + ++E+
Sbjct: 141 KFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRPHRAPITK-QNEQ 199
Query: 187 VAFCTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLNTFGD 246
A CT +D+ PLSGG +AFSTL+GRPSA++F+ SP LQ+WVT+T++ ++ RL+TFGD
Sbjct: 200 EAVCTDSHTDMRPLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGD 259
Query: 247 DIFKDPKVLQ-SYYYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCL 305
+ D ++ + SY+YAVSD VGGRCKCNGHA+ C D L C C+HNT G +C+RC
Sbjct: 260 ENEDDSELARDSYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCK 319
Query: 306 PFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGH--GGRCHHCRDHTAGPH 363
PF DRPW R TA A+EC+ CNC+ + C F+ EL++ +G GG C +CR +TAG H
Sbjct: 320 PFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRH 379
Query: 364 CERCQENFYH-----WDPRMPCQPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLP 417
C C+E +Y R C+ CDC G+ C+ TG C CK VTG C+RC
Sbjct: 380 CHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAK 439
Query: 418 GFHSLSEGGCRPC 430
G+ S PC
Sbjct: 440 GYQQ-SRSPIAPC 451
Score = 83.6 bits (205), Expect = 1e-15
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 18/161 (11%)
Query: 809 QCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYG---SALAPRPADKCMP 865
+C+C+G+ D L C HNT G C+ C+ Y R A++C+
Sbjct: 284 RCKCNGHAARCVRDRDDSL---VCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVA 340
Query: 866 CSCHPQGSVSE-QMPCDPVTGQCS------CLPHVTARDCSRCYPGFF-----DLQPGRG 913
C+C+ M ++G+ S C + R C C G++ + +
Sbjct: 341 CNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKA 400
Query: 914 CRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGF 954
C++C CHP+G+ C+ TGQC C+ GVTG C+RC G+
Sbjct: 401 CKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
Score = 78.2 bits (191), Expect = 6e-14
Identities = 57/196 (29%), Positives = 79/196 (40%), Gaps = 28/196 (14%)
Query: 707 CTCNQHGT-C---DPNTGICVCSHHTEGPSCERCLPGFYGNPF----AGQADDCQPCPCP 758
C CN H C ++ +C C H+T GP C+RC P Y P+ A +A++C C C
Sbjct: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
Query: 759 GQS-ACTTIPESREV-------VCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQC 810
+ C E ++ VC +C GR C C +G++ D H + C C
Sbjct: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKAC 404
Query: 811 QCSGNVDPNAVG-NCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCH 869
C A G C+ +G C C TG C C +G+ S P C+
Sbjct: 405 DCH---PVGAAGKTCNQTTGQC-PCKDGVTGITCNRCAKGYQQSR---SPIAPCIKIPVA 457
Query: 870 P----QGSVSEQMPCD 881
P SV E CD
Sbjct: 458 PPTTAASSVEEPEDCD 473
Score = 74.7 bits (182), Expect = 7e-13
Identities = 48/169 (28%), Positives = 70/169 (41%), Gaps = 43/169 (25%)
Query: 327 CNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWD---------PR 377
C C+G + C DR+ CR +TAGP C+RC+ +H+D
Sbjct: 285 CKCNGHAARCVRDRD-------DSLVCDCRHNTAGPECDRCKP--FHYDRPWQRATAREA 335
Query: 378 MPCQPCDCQSAGSLHLQ-C------------DDTGTCA-CKPTVTGWKCDRCLPGFHS-- 421
C C+C +LH + C G C C+ G C C G++
Sbjct: 336 NECVACNC----NLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDM 391
Query: 422 ----LSEGGCRPCTCNPAGSLD-TCDPRSGRCPCKENVEGNLCDRCRPG 465
C+ C C+P G+ TC+ +G+CPCK+ V G C+RC G
Sbjct: 392 GKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKG 440
Score = 62.4 bits (150), Expect = 3e-09
Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 25/135 (18%)
Query: 887 CSCLPHVTARDCSRCYPGFFD-------LQPGRGCRSCKCHPLGSQEDQCHPKT------ 933
C C + +C RC P +D + C +C C+ L ++ + + +
Sbjct: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN-LHARRCRFNMELYKLSGR 362
Query: 934 ---GQC-TCRPGVTGQACDRCQLGFF---GFSI---KGCRACRCSPLGAASAQCHE-NGT 982
G C CR G+ C C+ G++ G I K C+AC C P+GAA C++ G
Sbjct: 363 KSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQ 422
Query: 983 CVCRPGFEGYKCDRC 997
C C+ G G C+RC
Sbjct: 423 CPCKDGVTGITCNRC 437
Score = 50.8 bits (120), Expect = 1e-05
Identities = 41/145 (28%), Positives = 54/145 (37%), Gaps = 29/145 (20%)
Query: 672 ICSCPTGYTGQFCESCAP-GYKREMPQGGPYAS--CVPCTCNQHG-TCDPNT-------- 719
+C C G C+ C P Y R + + CV C CN H C N
Sbjct: 303 VCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGR 362
Query: 720 ---GICV-CSHHTEGPSCERCLPGFY---GNPF----AGQADDCQPCPCPGQSACTTIPE 768
G+C+ C H+T G C C G+Y G P A +A DC P G++ T +
Sbjct: 363 KSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQ 422
Query: 769 SREVVCTHCPPGQRGRRCEVCDDGF 793
C G G C C G+
Sbjct: 423 ------CPCKDGVTGITCNRCAKGY 441
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 307 bits (786), Expect = 6e-83
Identities = 254/995 (25%), Positives = 413/995 (41%), Gaps = 170/995 (17%)
Query: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT-CDPNTGICV-CSHHTEG 730
C C G + C+ C PG+ + SC PC CN H CDP TG C+ C +T G
Sbjct: 840 CHCFQGVYARQCDRCLPGH-------WGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMG 892
Query: 731 PSCERCLPGFYGNPFAGQADDCQPCPCPG--------QSACTTIPESREVVCTHCPPGQR 782
+CERCL G+YG+P G D C+PCPCP +C P + ++ C C PG
Sbjct: 893 HNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACV-CDPGYI 951
Query: 783 GRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDH 842
G RC+ C G+FG+P + G QPC QC N+D CD +G CL+CL++T G+H
Sbjct: 952 GSRCDDCASGYFGNPSEVGGSCQPC---QCHNNIDTTDPEACDKETGRCLKCLYHTEGEH 1008
Query: 843 CEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQM-----PCDPVTGQCSCLPHVTARD 897
C+ C+ G+YG AL C C C+ G+V E CD TGQC CLP+V ++
Sbjct: 1009 CQFCRFGYYGDALQ----QDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQN 1064
Query: 898 CSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGF 957
C RC P + L G GC C C+ S C+ TGQC C PG G+ C CQ F+G
Sbjct: 1065 CDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGD 1124
Query: 958 SIKGCRACRCSPLGAASAQCHEN-GTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSC 1016
CRAC C P G + QC ++ G CVC G EG +CD+C + + C C C
Sbjct: 1125 PDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGY--SGVFPDCTPCHQC 1182
Query: 1017 YALVKEEAAKLKARLTLTEGWLQGSDCGSPWGPLDILLGEAPRGDVYQGHHLLPGAREAF 1076
+AL W D+++ E L F
Sbjct: 1183 FAL-----------------W-------------DVIIAE------------LTNRTHRF 1200
Query: 1077 LEQMMSLE--GAVKAAREQLQRL-NKGARCAQAGSQKTCTQ-LADLEAVLESSEEEILHA 1132
LE+ +L+ G + RE + + K + +Q + L ++ + E +E+ I
Sbjct: 1201 LEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSPAAEPLKNIGNLFEEAEKLIKDV 1260
Query: 1133 AAILASLEI-----PQEGPSQPTKWSHLATEARALARSHRDTATK---IAATAWRALLAS 1184
++A +E+ + S + L TEA +L + ++ A + I + R L S
Sbjct: 1261 TEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAEQLEFIKNSDIRGALDS 1320
Query: 1185 NTSYALLWNLLEGRVALET------------QRD-LEDRYQEVQAAQKALRTAVAEVLPE 1231
T Y + E RV T RD +ED E ++ K + A +L E
Sbjct: 1321 ITKYFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDE 1380
Query: 1232 AESVLATVQQVGADTAPYLALLASPGALPQKSRAEDLGLKAKALEKT--------VASWQ 1283
+ +Q + A + PGA ++ + E+ + +
Sbjct: 1381 ---LAGKLQSLDLSAAAEMTCGTPPGASCSETECGGPNCRTDEGERKCGGPGCGGLVTVA 1437
Query: 1284 HMATEAARTLQTAAQATLRQTEPLTKLHQEARAALTQASSSVQAATVTVMGARTLL---- 1339
H A + A L + L + E L+K+ EA+ +A S + + + +
Sbjct: 1438 HNAWQKAMDLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSN 1497
Query: 1340 ------------------ADLEGMK------LQFPRPKDQAALQRKADSVSDR------- 1368
ADL+ ++ L+ P LQ + + +R
Sbjct: 1498 EELRNLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQV 1557
Query: 1369 --LLADTRKKTKQAERMLGNAAPLSSSAK-------------KKGREAEVLAKDSAKLAK 1413
+L + +AE +L A S SA ++ +A+V A+ + K A
Sbjct: 1558 EVILQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQAD 1617
Query: 1414 ALLRERKQAHRRASRLTSQTQATLQQASQQVLASEARRQELE--------EAERVGAGLS 1465
++ + T+ ++ TL ASQ++ E +EL+ EAE + +
Sbjct: 1618 EDIQGTQNLLTSIESETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVY 1677
Query: 1466 EMEQQIRESRISLEKDIETLSELLARLGSLDTHQAPAQALNETQWALERLRLQLGSPGSL 1525
++Q + + +L+ +++ + + L + T ++ A A + + + L S
Sbjct: 1678 TVKQSAEDVKKTLDGELDEKYKKVENLIAKKTEES-ADARRKAEMLQNEAKTLLAQANSK 1736
Query: 1526 QRKLSLLEQESQQQELQIQGFESDLAEIRADKQNL 1560
+ L LE++ + + ++ +LA + + ++L
Sbjct: 1737 LQLLKDLERKYEDNQRYLEDKAQELARLEGEVRSL 1771
Score = 246 bits (629), Expect = 1e-64
Identities = 162/492 (32%), Positives = 233/492 (47%), Gaps = 58/492 (11%)
Query: 35 CLPVFENAAFGRLAQAS--HTCG-SPPEDFCPHVGAAGAGAHCQRCDAADPQR------- 84
C P + GR + S TCG PE +C V C C++ DP
Sbjct: 35 CYPATGDLLIGRAQKLSVTSTCGLHKPEPYCI-VSHLQEDKKCFICNSQDPYHETLNPDS 93
Query: 85 HHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKFHTSRPES 144
H + +T F WWQS + GV+ +V I L L + T++ + F T RP +
Sbjct: 94 HLIENVVTTFAPNRLKIWWQSEN---GVE---NVTIQLDLEAEFHFTHLIMTFKTFRPAA 147
Query: 145 FAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPGEDERVAFCTSEFSDISPLSGGN 204
I + S W Y++++ C+ ++ ++ +D C S +SDI P + G
Sbjct: 148 MLIERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVDD---IICDSRYSDIEPSTEGE 204
Query: 205 VAFSTLEGRPSAYNFEE--SPGLQEWVTSTELLISLDRLNTFGDDIFKDP-KVLQSYYYA 261
V F L+ A+ E+ SP +Q + T L I +L+T GD++ ++ + YYYA
Sbjct: 205 VIFRALD---PAFKIEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYA 261
Query: 262 VSDFSVGGRCKCNGHASECGP------DVAGQLA--CRCQHNTTGTDCERCLPFFQDRPW 313
V D V G C C GHASEC P +V G + C C+HNT G +CE C+ F+ D PW
Sbjct: 262 VYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPW 321
Query: 314 ARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGH--GGRCHHCRDHTAGPHCERCQENF 371
++ C CNC+ S C FD ++ +TG+ GG C C+ +T G +CE+C+ +
Sbjct: 322 RPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFY 381
Query: 372 YHW---DPRMP--CQPCDCQSAGSLHLQ-CDD---------TGTCACKPTVTGWKCDRCL 416
Y D R P C+ C C AGS + CD G C CK V G CD C
Sbjct: 382 YQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCK 441
Query: 417 PGFHSLSEG---GCRPCTCNPAGSL---DTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQ 470
GF+ LS GC+ C CNP G++ + CD +G C CK V G CD+C P + L
Sbjct: 442 EGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLS 501
Query: 471 PHNPAGCSSCFC 482
++ GC C C
Sbjct: 502 -NDLDGCRPCDC 512
Score = 185 bits (470), Expect = 3e-46
Identities = 112/332 (33%), Positives = 151/332 (45%), Gaps = 45/332 (13%)
Query: 707 CTCNQHGT----CDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSA 762
C C+ G+ CDPN G C C + G +C RC PG +G +G C+PC C Q +
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSG----CKPCECHLQGS 828
Query: 763 CTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVG 822
C HC G R+C+ C G +G P C CQC+G+ D
Sbjct: 829 VNAFCNPVTGQC-HCFQGVYARQCDRCLPGHWGFP--------SCQPCQCNGHAD----- 874
Query: 823 NCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQM---P 879
+CDP++G CL C T G +CE C G+YG + D C PC C P G S +
Sbjct: 875 DCDPVTGECLNCQDYTMGHNCERCLAGYYGDPII-GSGDHCRPCPC-PDGPDSGRQFARS 932
Query: 880 C--DPVTGQ--CSCLPHVTARDCSRCYPGFF--DLQPGRGCRSCKCHPL--GSQEDQCHP 931
C DPVT Q C C P C C G+F + G C+ C+CH + + C
Sbjct: 933 CYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDK 992
Query: 932 KTGQC-TCRPGVTGQACDRCQLGFFGFSI-KGCRACRCSPLGAASAQCH--------ENG 981
+TG+C C G+ C C+ G++G ++ + CR C C+ LG C+ G
Sbjct: 993 ETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATG 1052
Query: 982 TCVCRPGFEGYKCDRCHDNFFLTADGTHCQQC 1013
C+C P G CDRC N + A GT C C
Sbjct: 1053 QCLCLPNVIGQNCDRCAPNTWQLASGTGCDPC 1084
Score = 160 bits (404), Expect = 1e-38
Identities = 106/315 (33%), Positives = 136/315 (43%), Gaps = 37/315 (11%)
Query: 671 EICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQ--------HGTC--DPNT- 719
E +C G CE C GY + P G C PC C +C DP T
Sbjct: 882 ECLNCQDYTMGHNCERCLAGYYGD-PIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTL 940
Query: 720 -GICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVV---CT 775
CVC G C+ C G++GNP + CQPC C + TT PE+ + C
Sbjct: 941 QLACVCDPGYIGSRCDDCASGYFGNP-SEVGGSCQPCQC-HNNIDTTDPEACDKETGRCL 998
Query: 776 HCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCS--GNVDPNAVGN---CDPLSGH 830
C G C+ C G++GD L Q C +C C+ G V + G+ CD +G
Sbjct: 999 KCLYHTEGEHCQFCRFGYYGDAL-----QQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQ 1053
Query: 831 CLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCL 890
CL CL N G +C+ C + A C PC+C+ S C+ TGQC C+
Sbjct: 1054 CL-CLPNVIGQNCDRCAPNTWQLA----SGTGCDPCNCNAAHSFGPS--CNEFTGQCQCM 1106
Query: 891 PHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRC 950
P R CS C F+ P CR+C C P G + QC TGQC C GV G CD+C
Sbjct: 1107 PGFGGRTCSECQELFWG-DPDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKC 1165
Query: 951 QLGFFGFSIKGCRAC 965
G+ G C C
Sbjct: 1166 TRGYSGV-FPDCTPC 1179
Score = 143 bits (361), Expect = 1e-33
Identities = 79/257 (30%), Positives = 119/257 (46%), Gaps = 25/257 (9%)
Query: 720 GICVCSHHTEGPSCERCLPGFYGNPF----AGQADDCQPCPCPGQSACTTIPESREV--- 772
G C+C H+T+G +CE C+ ++ P+ ++ C+ C C S + +
Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATG 355
Query: 773 -----VCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDP- 826
VC C GR CE C ++ P P C +C C N G CD
Sbjct: 356 NVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNE-GICDSY 414
Query: 827 -------LSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMP 879
++G C RC N G+HC+ C+EGFY L+ C C+C+P G++ P
Sbjct: 415 TDFSTGLIAGQC-RCKLNVEGEHCDVCKEGFYD--LSSEDPFGCKSCACNPLGTIPGGNP 471
Query: 880 CDPVTGQCSCLPHVTARDCSRCYPGFFDLQPG-RGCRSCKCHPLGSQEDQCHPKTGQCTC 938
CD TG C C VT + C +C P + L GCR C C G+ + C ++GQC+C
Sbjct: 472 CDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSC 531
Query: 939 RPGVTGQACDRCQLGFF 955
RP + G+ C+ + G++
Sbjct: 532 RPHMIGRQCNEVEPGYY 548
Score = 130 bits (328), Expect = 8e-30
Identities = 79/218 (36%), Positives = 107/218 (49%), Gaps = 23/218 (10%)
Query: 270 RCKCNGHASECGPDVAGQLACR---------CQHNTTGTDCERCLPFFQDRPWARGTAEA 320
+C CN H+ C D+A LA CQHNT G +CE+C PF+ P
Sbjct: 334 KCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHP--ERDIRD 391
Query: 321 AHECLPCNC--SGRSEECTFDRELFRSTGH-GGRCHHCRDHTAGPHCERCQENFYHWDPR 377
+ C C C +G E D STG G+C C+ + G HC+ C+E FY
Sbjct: 392 PNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCR-CKLNVEGEHCDVCKEGFYDLSSE 450
Query: 378 MP--CQPCDCQSAGSLH--LQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEG--GCRPC 430
P C+ C C G++ CD +TG C CK VTG CD+CLP LS GCRPC
Sbjct: 451 DPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPC 510
Query: 431 TCNPAGSLD-TCDPRSGRCPCKENVEGNLCDRCRPGTF 467
C+ G+L+ +C SG+C C+ ++ G C+ PG +
Sbjct: 511 DCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
Score = 126 bits (317), Expect = 1e-28
Identities = 64/155 (41%), Positives = 84/155 (54%), Gaps = 11/155 (7%)
Query: 864 MPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLG 923
+ C C PQGS+S CDP GQC C P+V R C+RC PG F P GC+ C+CH G
Sbjct: 771 LACECDPQGSLSSV--CDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPS-GCKPCECHLQG 827
Query: 924 SQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENGTC 983
S C+P TGQC C GV + CDRC G +GF C+ C+C+ G A G C
Sbjct: 828 SVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGF--PSCQPCQCN--GHADDCDPVTGEC 883
Query: 984 V-CRPGFEGYKCDRCHDNFF---LTADGTHCQQCP 1014
+ C+ G+ C+RC ++ + G HC+ CP
Sbjct: 884 LNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCP 918
Score = 122 bits (305), Expect = 4e-27
Identities = 86/290 (29%), Positives = 116/290 (40%), Gaps = 39/290 (13%)
Query: 641 PGPSPAGPVFLTEVRLTSARPGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGP 700
P P P GP + AR P + C C GY G C+ CA GY + G
Sbjct: 916 PCPCPDGP----DSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVG- 970
Query: 701 YASCVPCTCNQH------GTCDPNTGICV-CSHHTEGPSCERCLPGFYGNPFAGQADDCQ 753
SC PC C+ + CD TG C+ C +HTEG C+ C G+YG+ DC+
Sbjct: 971 -GSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDAL---QQDCR 1026
Query: 754 PCPCPGQSACTTIPESREVVCTH------CPPGQRGRRCEVCDDGFFGDPLGLFGHPQPC 807
C C + C C P G+ C+ C + G C
Sbjct: 1027 KCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASG-----TGC 1081
Query: 808 HQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCS 867
C C N + +C+ +G C +C+ G C CQE F+G P +C C
Sbjct: 1082 DPCNC--NAAHSFGPSCNEFTGQC-QCMPGFGGRTCSECQELFWGD-----PDVECRACD 1133
Query: 868 CHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSC 917
C P+G + Q CD TGQC C+ V C +C G+ + P C C
Sbjct: 1134 CDPRGIETPQ--CDQSTGQCVCVEGVEGPRCDKCTRGYSGVFP--DCTPC 1179
Score = 117 bits (292), Expect = 1e-25
Identities = 80/265 (30%), Positives = 111/265 (41%), Gaps = 45/265 (16%)
Query: 673 CSCPTGYTGQFCESCAPGYKREMP----QGGPYASCVPCTCNQH------------GTCD 716
C C G CE C Y ++P +G +C C CN+H T +
Sbjct: 298 CMCRHNTKGLNCELCMDFY-HDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGN 356
Query: 717 PNTGIC-VCSHHTEGPSCERCLPGFYGNPFAGQADD--CQPCPC-PGQSACTTIPESREV 772
+ G+C C H+T G +CE+C P +Y +P D C+ C C P S I +S
Sbjct: 357 VSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTD 416
Query: 773 VCTHCPPGQ-------RGRRCEVCDDGFFG----DPLGLFGHPQPCHQCQCSGNVDPNAV 821
T GQ G C+VC +GF+ DP G C C C+
Sbjct: 417 FSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFG-------CKSCACNPLGTIPGG 469
Query: 822 GNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCD 881
CD +GHC C TG HC+ C +G + D C PC C G+++ C
Sbjct: 470 NPCDSETGHCY-CKRLVTGQHCDQCLPEHWGLS---NDLDGCRPCDCDLGGALNNS--CF 523
Query: 882 PVTGQCSCLPHVTARDCSRCYPGFF 906
+GQCSC PH+ R C+ PG++
Sbjct: 524 AESGQCSCRPHMIGRQCNEVEPGYY 548
Score = 112 bits (279), Expect = 4e-24
Identities = 68/198 (34%), Positives = 86/198 (43%), Gaps = 20/198 (10%)
Query: 277 ASECGPD-VAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEE 335
A C D V QLAC C G+ C+ C + P +E C PC C +
Sbjct: 930 ARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNP-----SEVGGSCQPCQCHNNID- 983
Query: 336 CTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGSLH--- 392
T D E GRC C HT G HC+ C+ +Y + C+ C C G++
Sbjct: 984 -TTDPEACDK--ETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHC 1040
Query: 393 ----LQCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEG-GCRPCTCNPAGSL-DTCDPRS 445
QCD TG C C P V G CDRC P L+ G GC PC CN A S +C+ +
Sbjct: 1041 NGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFT 1100
Query: 446 GRCPCKENVEGNLCDRCR 463
G+C C G C C+
Sbjct: 1101 GQCQCMPGFGGRTCSECQ 1118
Score = 102 bits (253), Expect = 4e-21
Identities = 71/228 (31%), Positives = 95/228 (41%), Gaps = 24/228 (10%)
Query: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC- 329
C+CNGHA +C P V G+ CQ T G +CERCL + P + C PC C
Sbjct: 867 CQCNGHADDCDP-VTGE-CLNCQDYTMGHNCERCLAGYYGDP----IIGSGDHCRPCPCP 920
Query: 330 SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRM--PCQPCDCQS 387
G F R ++ C G C+ C ++ + CQPC C +
Sbjct: 921 DGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHN 980
Query: 388 AGSLH--LQCD-DTGTCA-CKPTVTGWKCDRCLPGFHSLS-EGGCRPCTCNPAGSLDT-- 440
CD +TG C C G C C G++ + + CR C CN G++
Sbjct: 981 NIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHC 1040
Query: 441 ------CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
CD +G+C C NV G CDRC P T+ L + GC C C
Sbjct: 1041 NGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLA--SGTGCDPCNC 1086
Score = 95.5 bits (236), Expect = 4e-19
Identities = 43/109 (39%), Positives = 56/109 (51%), Gaps = 7/109 (6%)
Query: 383 CDCQSAGSLHLQCDDTG-TCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDT- 440
C+C GSL CD G C C+P V G C+RC PG GC+PC C+ GS++
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAF 832
Query: 441 CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVC 489
C+P +G+C C + V CDRC PG + C C C GH+ C
Sbjct: 833 CNPVTGQCHCFQGVYARQCDRCLPGHWGF-----PSCQPCQCNGHADDC 876
Score = 95.1 bits (235), Expect = 5e-19
Identities = 80/277 (28%), Positives = 105/277 (37%), Gaps = 86/277 (31%)
Query: 266 SVGGRCKCNGHASECGPDVAGQLACRCQHNTTG--------------------------- 298
S+ C NG +C P+V G+ RC T G
Sbjct: 780 SLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQ 839
Query: 299 ---------TDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHG 349
C+RCLP P C PC C+G +++C
Sbjct: 840 CHCFQGVYARQCDRCLPGHWGFP----------SCQPCQCNGHADDC---------DPVT 880
Query: 350 GRCHHCRDHTAGPHCERCQENFYHWDPRM----PCQPCDC----QSAGSLHLQC-DDTGT 400
G C +C+D+T G +CERC +Y DP + C+PC C S C D T
Sbjct: 881 GECLNCQDYTMGHNCERCLAGYY-GDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVT 939
Query: 401 ----CACKPTVTGWKCDRCLPG-FHSLSE--GGCRPCTCNPAGSLDT-----CDPRSGRC 448
C C P G +CD C G F + SE G C+PC C+ ++DT CD +GRC
Sbjct: 940 LQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCH--NNIDTTDPEACDKETGRC 997
Query: 449 -PCKENVEGNLCDRCRPGTFN--LQPHNPAGCSSCFC 482
C + EG C CR G + LQ C C C
Sbjct: 998 LKCLYHTEGEHCQFCRFGYYGDALQ----QDCRKCVC 1030
Score = 82.4 bits (202), Expect = 3e-15
Identities = 73/245 (29%), Positives = 91/245 (37%), Gaps = 60/245 (24%)
Query: 268 GGRCKCNGH---ASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGT-AEAAHE 323
G C+C+ +S C P+ GQ C+C+ N G C RC P GT
Sbjct: 770 GLACECDPQGSLSSVCDPN-GGQ--CQCRPNVVGRTCNRCAP---------GTFGFGPSG 817
Query: 324 CLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP-CQP 382
C PC C + F + G+CH C C+RC HW P CQP
Sbjct: 818 CKPCECHLQGSVNAFCNPVT------GQCH-CFQGVYARQCDRCLPG--HWG--FPSCQP 866
Query: 383 CDCQSAGSLHLQCDD-TGTCA-CKPTVTGWKCDRCLPGFHS---LSEGG-CRPCTCNPAG 436
C C CD TG C C+ G C+RCL G++ + G CRPC C P G
Sbjct: 867 CQCNGHAD---DCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPC-PDG 922
Query: 437 SLDTCDPRSGR----------------CPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSC 480
P SGR C C G+ CD C G F C C
Sbjct: 923 ------PDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPC 976
Query: 481 FCYGH 485
C+ +
Sbjct: 977 QCHNN 981
Score = 47.8 bits (112), Expect = 9e-05
Identities = 27/85 (31%), Positives = 33/85 (38%), Gaps = 7/85 (8%)
Query: 661 PGLSPPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHG----TCD 716
PG +P S C C TGQ C+ C P C PC C+ G +C
Sbjct: 467 PGGNPCDSETGHCYCKRLVTGQHCDQCLP---EHWGLSNDLDGCRPCDCDLGGALNNSCF 523
Query: 717 PNTGICVCSHHTEGPSCERCLPGFY 741
+G C C H G C PG+Y
Sbjct: 524 AESGQCSCRPHMIGRQCNEVEPGYY 548
>gi|5453810 netrin 3 [Homo sapiens]
Length = 580
Score = 306 bits (783), Expect = 1e-82
Identities = 166/419 (39%), Positives = 219/419 (52%), Gaps = 32/419 (7%)
Query: 25 CYDGAGRPQRCLPVFENAAFGRLAQASHTCGSPPEDFCPHVGAAGAGAHCQRCDAADPQR 84
C+D G P+ C+P NAA GR AS TCG P + CDA+DP+R
Sbjct: 30 CHDEGGAPRGCVPGLVNAALGREVLASSTCGRPAT---------------RACDASDPRR 74
Query: 85 HHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKFHTSRPES 144
H+ + LT W+S S+ + P +V +T+ LGKA+E+ +V L+F ++ P S
Sbjct: 75 AHSPALLTSPGGTASPLCWRSESLP---RAPLNVTLTVPLGKAFELVFVSLRFCSAPPAS 131
Query: 145 FAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPGEDERVAFCTSEFSDISPLSGGN 204
A+ K W P F+S+ C YGR P A C P G
Sbjct: 132 VALLKSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEALCFPA-PLAQPDGSGL 190
Query: 205 VAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIFKDPKVLQSYYYAVSD 264
+AFS + P + + SP LQ+WVT+T++ + L R +T GD +D + + Y YA +D
Sbjct: 191 LAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPSTAGDP--RDMEAVVPYSYAATD 248
Query: 265 FSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHEC 324
VGGRCKCNGHAS C D G L C C+H T G DC RC PF+ DRPW R TA +H C
Sbjct: 249 LQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHAC 308
Query: 325 LPCNCSGRSEECTFDRELFRSTGH--GGRCHHCRDHTAGPHCERCQENFYHWDP------ 376
L C+C+G + C F+ EL+R +G GG C +CR +TAG HC C+E FY DP
Sbjct: 309 LACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYR-DPGRALSD 367
Query: 377 RMPCQPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNP 434
R C+ CDC G+ C+ TG C CK VTG C+RC PGF S PC P
Sbjct: 368 RRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQ-SRSPVAPCVKTP 425
Score = 83.2 bits (204), Expect = 2e-15
Identities = 51/163 (31%), Positives = 72/163 (44%), Gaps = 22/163 (13%)
Query: 809 QCQCSGNVDPNAVGNCDPLSGHCL-RCLHNTTGDHCEHCQEGFY----GSALAPRPADKC 863
+C+C+G+ + GH + C H T G C C+ FY R + C
Sbjct: 254 RCKCNGHASRCLLDT----QGHLICDCRHGTEGPDCGRCKP-FYCDRPWQRATARESHAC 308
Query: 864 MPCSCHPQGSVSE-QMPCDPVTGQCS------CLPHVTARDCSRCYPGFFD-----LQPG 911
+ CSC+ M ++G+ S C + R C C GF+ L
Sbjct: 309 LACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDR 368
Query: 912 RGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGF 954
R CR+C CHP+G+ C+ TGQC C+ GVTG C+RC GF
Sbjct: 369 RACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411
Score = 81.6 bits (200), Expect = 5e-15
Identities = 78/282 (27%), Positives = 98/282 (34%), Gaps = 44/282 (15%)
Query: 640 SPGPSPAGPVFLTEVRLTSARPGLSPPAS-----WVEICSCPTGYTGQFCESCAPGYKRE 694
+P P G L S+ PGL +S WV T G R+
Sbjct: 180 APLAQPDGSGLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLT----RPSTAGDPRD 235
Query: 695 MPQGGPYASCVP-------CTCNQHGT-CDPNTG---ICVCSHHTEGPSCERCLPGFYGN 743
M PY+ C CN H + C +T IC C H TEGP C RC P +
Sbjct: 236 MEAVVPYSYAATDLQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDR 295
Query: 744 PF----AGQADDCQPCPCPGQSA-CTTIPESREV-------VCTHCPPGQRGRRCEVCDD 791
P+ A ++ C C C G + C E + VC +C GR C C +
Sbjct: 296 PWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCRE 355
Query: 792 GFFGDPLGLFGHPQPCHQCQCSGNVDPNAVG-NCDPLSGHCLRCLHNTTGDHCEHCQEGF 850
GF+ DP + C C C A G C+ +G C C TG C C GF
Sbjct: 356 GFYRDPGRALSDRRACRACDCH---PVGAAGKTCNQTTGQC-PCKDGVTGLTCNRCAPGF 411
Query: 851 YGSALAPRPADKCMPCSCHP-QGSVSEQMPCDPVTGQCSCLP 891
S PC P G + P P C P
Sbjct: 412 QQS------RSPVAPCVKTPIPGPTEDSSPVQPQDCDSHCKP 447
Score = 65.5 bits (158), Expect = 4e-10
Identities = 41/141 (29%), Positives = 57/141 (40%), Gaps = 29/141 (20%)
Query: 887 CSCLPHVTARDCSRCYPGFFD-------LQPGRGCRSCKCHPLGSQEDQCH--------- 930
C C DC RC P + D + C +C C+ +C
Sbjct: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN---GHARRCRFNMELYRLS 330
Query: 931 --PKTGQC-TCRPGVTGQACDRCQLGFF---GFSI---KGCRACRCSPLGAASAQCHE-N 980
G C CR G+ C C+ GF+ G ++ + CRAC C P+GAA C++
Sbjct: 331 GRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTT 390
Query: 981 GTCVCRPGFEGYKCDRCHDNF 1001
G C C+ G G C+RC F
Sbjct: 391 GQCPCKDGVTGLTCNRCAPGF 411
Score = 35.0 bits (79), Expect = 0.57
Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 8/67 (11%)
Query: 430 CTCNPAGSLDTCDPRSGR-CPCKENVEGNLCDRCRPGTFNLQPHNPA------GCSSCFC 482
C CN S D + C C+ EG C RC+P + +P A C +C C
Sbjct: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCD-RPWQRATARESHACLACSC 313
Query: 483 YGHSKVC 489
GH++ C
Sbjct: 314 NGHARRC 320
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 305 bits (781), Expect = 2e-82
Identities = 279/981 (28%), Positives = 421/981 (42%), Gaps = 129/981 (13%)
Query: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT-CDPNTGICV-CSHHTEG 730
C C TG G C+ C G Q G + SC PC CN H C+ +TG C+ C HT G
Sbjct: 850 CLCRTGAFGLRCDRCQRG------QWG-FPSCRPCVCNGHADECNTHTGACLGCRDHTGG 902
Query: 731 PSCERCLPGFYGNPFAGQADDCQPCPCPG--------QSACTTIPESREVVCTHCPPGQR 782
CERC+ GF+G+P C+PCPCP ++C S+++VC HC G
Sbjct: 903 EHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVC-HCRAGYT 961
Query: 783 GRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDH 842
G RCE C G FGDP G C C+CSGN+DP CDP +G CLRCLH+T G H
Sbjct: 962 GLRCEACAPGHFGDPSRPGGR---CQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPH 1018
Query: 843 CEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMP------CDPVTGQCSCLPHVTAR 896
C HC+ GF+G A C C+C+ G+ +Q P CDP +GQC CLP+V
Sbjct: 1019 CAHCKPGFHGQAAR----QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGP 1074
Query: 897 DCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFG 956
C RC P F++L G GC+ C CHP ++ C+ TGQC CR G G+ C CQ +G
Sbjct: 1075 SCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWG 1134
Query: 957 FSIKGCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDRCHDNFFLTADGTH-CQQCP 1014
C AC C G + QCH G C CRPG G +CD+C F H C C
Sbjct: 1135 DPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPCHACF 1194
Query: 1015 SCYALVKEEAAKLKARL-----TLTEGWLQGSDCGSPWGPLDILLGEAPRGDVYQGHHLL 1069
+ V ++ A RL L + + G+ S W + L + QG +
Sbjct: 1195 GDWDRVVQDLAARTQRLEQRAQELQQTGVLGAFESSFWHMQEKL-------GIVQG---I 1244
Query: 1070 PGAREAFLEQMMSLEGAVKAAREQLQRLNKGARCAQAGSQKTCTQLADLEAVLESSEEEI 1129
GAR L A + R ++ + L LEA L ++E
Sbjct: 1245 VGARNTSAASTAQLVEATEELRREIGEATE--------------HLTQLEADLTDVQDEN 1290
Query: 1130 LHAAAILASLEIPQEGPS----QPTKWSHLATEARALAR--SHRDTATKIAATAWRALLA 1183
+A L+ LE + + Q + L + L S R ++ A RA +
Sbjct: 1291 FNANHALSGLERDRLALNLTLRQLDQHLDLLKHSNFLGAYDSIRHAHSQSAEAERRANTS 1350
Query: 1184 SNTSYALLWNLLEGRVALETQRDL--EDRYQEVQAAQKAL-----------RTAVAEVLP 1230
+ + + N R E D ED + A Q+AL T + E++
Sbjct: 1351 ALAVPSPVSNSASARHRTEALMDAQKEDFNSKHMANQRALGKLSAHTHTLSLTDINELVC 1410
Query: 1231 EA--ESVLATVQQVGA-----DTAPYLALLASPGALPQKSRAEDLGLKAKA-LEKTVASW 1282
A ++ AT GA D P L+ GA A +A L++ +A
Sbjct: 1411 GAPGDAPCATSPCGGAGCRDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQRALAEG 1470
Query: 1283 QHMATEAARTLQTAAQATLRQTEPLTKLHQEARAALTQASSSVQAATVTVM------GAR 1336
+ + A T + A++A R L K + +R + QA+ +Q +V GA
Sbjct: 1471 GSILSRVAETRRQASEAQQRAQAALDKAN-ASRGQVEQANQELQELIQSVKDFLNQEGAD 1529
Query: 1337 TLLADLEGMK-LQFPRPKDQAALQRKADSVSDR---------LLADTRKKTKQAERMLGN 1386
++ + L+ P +Q A ++++R +LA T ++AE++L +
Sbjct: 1530 PDSIEMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQD 1589
Query: 1387 AAPLSSSAKKKGREAEVL--AKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQASQQV 1444
A S A+ + ++AE + A + A+ A+ + + A R A T T+ TL Q +++
Sbjct: 1590 ARRARSWAEDEKQKAETVQAALEEAQRAQGI---AQGAIRGAVADTRDTEQTLYQVQERM 1646
Query: 1445 LASE-ARRQELEEAERVGAGLSEMEQQIRESRISLEKDIETL---------SELLARLGS 1494
+E A E A ++ A L ++ + + ++ ET +E L R
Sbjct: 1647 AGAERALSSAGERARQLDALLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPL 1706
Query: 1495 LDTHQA-------PAQALNETQWALERLRLQLGS-PGSLQRKLSLLEQESQQQELQIQGF 1546
D +Q AQ + Q E+LR + + Q KL L++ E +
Sbjct: 1707 GDQYQTVKALAERKAQGVLAAQARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERAL 1766
Query: 1547 ESDLAEIRADKQNLEAILHSL 1567
ES A++ + + ++L ++
Sbjct: 1767 ESKAAQLDGLEARMRSVLQAI 1787
Score = 259 bits (661), Expect = 2e-68
Identities = 171/515 (33%), Positives = 238/515 (46%), Gaps = 72/515 (13%)
Query: 14 APRAAGAGMGACYDGAGRPQRCLPVFENAAFGRLAQ--ASHTCG-SPPEDFCPHVGAAGA 70
AP G G+CY G + GR + AS TCG + P+ +C V
Sbjct: 36 APDVPGCSRGSCYPATG----------DLLVGRADRLTASSTCGLNGPQPYCI-VSHLQD 84
Query: 71 GAHCQRCDAA-------DPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLR 123
C CD+ +P H + +T F Q + WWQS + G+ +V I L
Sbjct: 85 EKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAWWQSEN---GIP---AVTIQLD 138
Query: 124 LGKAYEITYVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPGE 183
L + T++ + F T RP + + + + W Y+++S C + G L P
Sbjct: 139 LEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWHVYRYFSYDCGADF---PGVPLAPPR 195
Query: 184 DERVAFCTSEFSDISPLSGGNVAFSTLEGR---PSAYNFEESPGLQEWVTSTELLISLDR 240
C S +S+I P + G V + L+ P Y S +Q + T L ++L R
Sbjct: 196 HWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPY----SSRIQNLLKITNLRVNLTR 251
Query: 241 LNTFGDDIFKDPK--VLQSYYYAVSDFSVGGRCKCNGHASECGPDVAGQL--------AC 290
L+T GD++ DP+ + + YYYA+ + V G C C GHASEC P AC
Sbjct: 252 LHTLGDNLL-DPRREIREKYYYALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHGAC 310
Query: 291 RCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGH-- 348
C+HNT G +CE+C F++D PW +H C C C G + C FD ++ ++G+
Sbjct: 311 ICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVS 370
Query: 349 GGRCHHCRDHTAGPHCERCQENFYH---WDPRMP--CQPCDCQSAGSLH-LQCDD----- 397
GG C C+ +TAG HCE C+ FY D R P C+ CDC GS +CD
Sbjct: 371 GGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPA 430
Query: 398 ----TGTCACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNPAGSL---DTCDPRSGR 447
+G C CK V G +C +C GF LS GCR C CN G++ CDP SG
Sbjct: 431 LGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGS 490
Query: 448 CPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
C CK V G CDRC PG + L H+ GC C C
Sbjct: 491 CYCKRLVTGRGCDRCLPGHWGLS-HDLLGCRPCDC 524
Score = 186 bits (471), Expect = 2e-46
Identities = 122/388 (31%), Positives = 156/388 (40%), Gaps = 96/388 (24%)
Query: 701 YASCVPCTCNQHGT----CDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCP 756
Y +PC CN G+ C+P+ G C+C G C+ C PG+YG G CQ C
Sbjct: 777 YNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTG----CQACQ 832
Query: 757 CPGQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNV 816
C + A +++ E C C G G RC+ C G +G P C C C+G+
Sbjct: 833 CSHEGALSSLCEKTSGQCL-CRTGAFGLRCDRCQRGQWGFP--------SCRPCVCNGHA 883
Query: 817 DPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPC---------- 866
D C+ +G CL C +T G+HCE C GF+G P +C PC
Sbjct: 884 D-----ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPY-GGQCRPCPCPEGPGSQR 937
Query: 867 ----SCHPQGSVSEQMPC--------------------------------------DPV- 883
SCH Q S+Q+ C DP+
Sbjct: 938 HFATSCH-QDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMD 996
Query: 884 -------TGQC-SCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGS------QEDQC 929
TGQC CL H C+ C PGF + C C C+ LG+ DQC
Sbjct: 997 PDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQC 1056
Query: 930 H--PKTGQCTCRPGVTGQACDRCQLGFFGF-SIKGCRACRCSPLGAASAQCHE-NGTCVC 985
H P +GQC C P V G +CDRC F+ S GC+ C C P A C+E G C C
Sbjct: 1057 HCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHC 1116
Query: 986 RPGFEGYKCDRCHDNFFLTADGTHCQQC 1013
R GF G C C + G C C
Sbjct: 1117 RAGFGGRTCSECQE-LHWGDPGLQCHAC 1143
Score = 169 bits (429), Expect = 1e-41
Identities = 147/506 (29%), Positives = 189/506 (37%), Gaps = 118/506 (23%)
Query: 382 PCDCQSAGSLHLQCDDTG-TCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDT 440
PC C GSL +C+ G C CKP V G +CD C PG++ GC+ C C+ G+L +
Sbjct: 782 PCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSS 841
Query: 441 -CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVCASTAQFQVHH 499
C+ SG+C C+ G CDRC+ G + C C C GH+ C
Sbjct: 842 LCEKTSGQCLCRTGAFGLRCDRCQRGQWGF-----PSCRPCVCNGHADEC---------- 886
Query: 500 ILSDFHQGAEGWWARSVGGSEHPPQWSPNGVLLSPEDEEELTAPEKFLGDQRFSYGQPLI 559
+ H GA R G EH + F GD R YG
Sbjct: 887 ---NTHTGA-CLGCRDHTGGEHCERCIAG-----------------FHGDPRLPYGGQC- 924
Query: 560 LTFRVPPGDSPLPVQLRLEGTGLALSLRHSSLSGPQDAGHPREVELRFHLQETSEDVAPP 619
P P P+ G R H E S+ +
Sbjct: 925 ---------RPCPC--------------------PEGPGSQRHFATSCHQDEYSQQIV-- 953
Query: 620 LPPFHFQRLLANLTSLRLRV-SPG----PS-PAGPVFLTEV--RLTSARPGLSPPASWVE 671
A T LR +PG PS P G L E + P P + +
Sbjct: 954 ------CHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTG-Q 1006
Query: 672 ICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT------------CDPNT 719
C G C C PG+ + + SC CTCN GT CDP++
Sbjct: 1007 CLRCLHHTEGPHCAHCKPGFHGQAAR----QSCHRCTCNLLGTNPQQCPSPDQCHCDPSS 1062
Query: 720 GICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPC-PGQSACTTIPESREVVCTHCP 778
G C C + +GPSC+RC P F+ N +G CQPC C P ++ T E HC
Sbjct: 1063 GQCPCLPNVQGPSCDRCAPNFW-NLTSGHG--CQPCACHPSRARGPTCNEFTGQ--CHCR 1117
Query: 779 PGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQC-SGNVDPNAVGNCDPLSGHCLRCLHN 837
G GR C C + +GDP GL CH C C S +D C +GHC C
Sbjct: 1118 AGFGGRTCSECQELHWGDP-GL-----QCHACDCDSRGID---TPQCHRFTGHC-SCRPG 1167
Query: 838 TTGDHCEHCQEGFYGSALAPRPADKC 863
+G C+ C GF G A P C
Sbjct: 1168 VSGVRCDQCARGFSGIFPACHPCHAC 1193
Score = 160 bits (405), Expect = 9e-39
Identities = 90/259 (34%), Positives = 124/259 (47%), Gaps = 29/259 (11%)
Query: 720 GICVCSHHTEGPSCERCLPGFYGNPFA----GQADDCQPCPCPGQS-AC----TTIPESR 770
G C+C H+T G +CE+C + P+ G + C+ C C G + +C S
Sbjct: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASG 367
Query: 771 EV---VCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCS--GNVDPNAVGNCD 825
V VC C GR CE+C F+ DP P C C C G+ D G CD
Sbjct: 368 NVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDG---GRCD 424
Query: 826 P--------LSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQ 877
+SG C RC + G C+ C++GF+G +++ R C C C+ +G+V
Sbjct: 425 SHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFGLSISDRLG--CRRCQCNARGTVPGS 481
Query: 878 MPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPG-RGCRSCKCHPLGSQEDQCHPKTGQC 936
PCDP +G C C VT R C RC PG + L GCR C C G+ + QC TGQC
Sbjct: 482 TPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQC 541
Query: 937 TCRPGVTGQACDRCQLGFF 955
CR + G+ C++ Q G+F
Sbjct: 542 HCRQHMVGRRCEQVQPGYF 560
Score = 151 bits (381), Expect = 5e-36
Identities = 101/288 (35%), Positives = 123/288 (42%), Gaps = 35/288 (12%)
Query: 742 GNPFA-GQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPL-- 798
GN F G A +C P PG A +C H RG CE C D + P
Sbjct: 281 GNCFCYGHASEC--APAPGAPAHAEGMVHGACICKH---NTRGLNCEQCQDFYRDLPWRP 335
Query: 799 GLFGHPQPCHQCQCSGNVDPN--------AVGNCDPLSGHCLRCLHNTTGDHCEHCQEGF 850
GH C +C+C G+ A GN G C C HNT G HCE C+ F
Sbjct: 336 AEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVS--GGVCDGCQHNTAGRHCELCRPFF 393
Query: 851 YGSALAP-RPADKCMPCSCHPQGSVSEQMPCDP--------VTGQCSCLPHVTARDCSRC 901
Y R C C C P GS + CD V+GQC C HV C +C
Sbjct: 394 YRDPTKDLRDPAVCRSCDCDPMGS-QDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQC 452
Query: 902 YPGFFDLQPGR--GCRSCKCHPLGSQEDQ--CHPKTGQCTCRPGVTGQACDRCQLGFFGF 957
GFF L GCR C+C+ G+ C P +G C C+ VTG+ CDRC G +G
Sbjct: 453 RDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGL 512
Query: 958 S--IKGCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDRCHDNFF 1002
S + GCR C C GA QC E G C CR G +C++ +F
Sbjct: 513 SHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 135 bits (340), Expect = 3e-31
Identities = 85/264 (32%), Positives = 109/264 (41%), Gaps = 41/264 (15%)
Query: 672 ICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQH------GTCDPNTGICV-C 724
+C C GYTG CE+CAPG+ + + P C C C+ + CDP+TG C+ C
Sbjct: 953 VCHCRAGYTGLRCEACAPGHFGDPSR--PGGRCQLCECSGNIDPMDPDACDPHTGQCLRC 1010
Query: 725 SHHTEGPSCERCLPGFYGNPFAGQADDC-------QPCPCPGQSACTTIPESREVVCTHC 777
HHTEGP C C PGF+G C P CP C P S + C
Sbjct: 1011 LHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCL-- 1068
Query: 778 PPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHN 837
P +G C+ C F+ G P CH + G C+ +G C C
Sbjct: 1069 -PNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARG-------PTCNEFTGQC-HCRAG 1119
Query: 838 TTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARD 897
G C CQE +G P +C C C +G + Q C TG CSC P V+
Sbjct: 1120 FGGRTCSECQELHWGD-----PGLQCHACDCDSRGIDTPQ--CHRFTGHCSCRPGVSGVR 1172
Query: 898 CSRCYPGFFDLQPGRGCRSCKCHP 921
C +C GF + P CHP
Sbjct: 1173 CDQCARGFSGIFPA-------CHP 1189
Score = 124 bits (311), Expect = 7e-28
Identities = 76/224 (33%), Positives = 98/224 (43%), Gaps = 36/224 (16%)
Query: 277 ASECGPD-VAGQLACRCQHNTTGTDCERCLP-FFQD--RPWARGTAEAAHECLPCNCSGR 332
A+ C D + Q+ C C+ TG CE C P F D RP R C C CSG
Sbjct: 940 ATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGR--------CQLCECSGN 991
Query: 333 SEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGSLH 392
+ D H G+C C HT GPHC C+ F+ R C C C G+
Sbjct: 992 IDPMDPDA----CDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNP 1047
Query: 393 LQC---------DDTGTCACKPTVTGWKCDRCLPGFHSLSEG-GCRPCTCNPAGSL-DTC 441
QC +G C C P V G CDRC P F +L+ G GC+PC C+P+ + TC
Sbjct: 1048 QQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTC 1107
Query: 442 DPRSGRCPCKENVEGNLCDRCRP---GTFNLQPHNPAGCSSCFC 482
+ +G+C C+ G C C+ G LQ C +C C
Sbjct: 1108 NEFTGQCHCRAGFGGRTCSECQELHWGDPGLQ------CHACDC 1145
Score = 118 bits (296), Expect = 4e-26
Identities = 89/292 (30%), Positives = 109/292 (37%), Gaps = 103/292 (35%)
Query: 271 CKCN--GHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCN 328
C+C+ G S +GQ C C+ G C+RC Q W + C PC
Sbjct: 831 CQCSHEGALSSLCEKTSGQ--CLCRTGAFGLRCDRC----QRGQWGFPS------CRPCV 878
Query: 329 CSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP----CQPCD 384
C+G ++EC H G C CRDHT G HCERC F H DPR+P C+PC
Sbjct: 879 CNGHADECNT---------HTGACLGCRDHTGGEHCERCIAGF-HGDPRLPYGGQCRPCP 928
Query: 385 CQS--------------------------AGSLHLQCD------------DTGTC----- 401
C AG L+C+ G C
Sbjct: 929 CPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCEC 988
Query: 402 ----------ACKP----------TVTGWKCDRCLPGFH-SLSEGGCRPCTCN------- 433
AC P G C C PGFH + C CTCN
Sbjct: 989 SGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQ 1048
Query: 434 --PAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCY 483
P+ CDP SG+CPC NV+G CDRC P +NL + GC C C+
Sbjct: 1049 QCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGH--GCQPCACH 1098
Score = 117 bits (293), Expect = 9e-26
Identities = 62/155 (40%), Positives = 79/155 (50%), Gaps = 11/155 (7%)
Query: 864 MPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLG 923
+PC C+PQGS+S + C+P GQC C P V R C C PG++ P GC++C+C G
Sbjct: 781 LPCQCNPQGSLSSE--CNPHGGQCLCKPGVVGRRCDLCAPGYYGFGP-TGCQACQCSHEG 837
Query: 924 SQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENGTC 983
+ C +GQC CR G G CDRCQ G +GF CR C C+ G A G C
Sbjct: 838 ALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGF--PSCRPCVCN--GHADECNTHTGAC 893
Query: 984 V-CRPGFEGYKCDRCHDNFF---LTADGTHCQQCP 1014
+ CR G C+RC F G C+ CP
Sbjct: 894 LGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCP 928
Score = 109 bits (273), Expect = 2e-23
Identities = 82/242 (33%), Positives = 110/242 (45%), Gaps = 40/242 (16%)
Query: 810 CQCSGNVD-----PNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADK-- 862
C C G+ P A + + + C HNT G +CE CQ+ FY L RPA+
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQD-FYRD-LPWRPAEDGH 340
Query: 863 ---CMPCSCHPQG-----SVSEQMPCDPVTGQ-CSCLPHVTA-RDCSRCYPGFF-----D 907
C C CH ++ + V+G C H TA R C C P F+ D
Sbjct: 341 SHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKD 400
Query: 908 LQPGRGCRSCKCHPLGSQED-QCHPK--------TGQCTCRPGVTGQACDRCQLGFFGFS 958
L+ CRSC C P+GSQ+ +C +GQC C+ V G C +C+ GFFG S
Sbjct: 401 LRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLS 460
Query: 959 IK---GCRACRCSPLGA--ASAQCHEN-GTCVCRPGFEGYKCDRC-HDNFFLTADGTHCQ 1011
I GCR C+C+ G S C N G+C C+ G CDRC ++ L+ D C+
Sbjct: 461 ISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCR 520
Query: 1012 QC 1013
C
Sbjct: 521 PC 522
Score = 95.5 bits (236), Expect = 4e-19
Identities = 58/165 (35%), Positives = 76/165 (46%), Gaps = 23/165 (13%)
Query: 325 LPCNCSGR---SEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQ 381
LPC C+ + S EC HGG+C C+ G C+ C +Y + P CQ
Sbjct: 781 LPCQCNPQGSLSSECN---------PHGGQCL-CKPGVVGRRCDLCAPGYYGFGPT-GCQ 829
Query: 382 PCDCQSAGSLHLQCDDT-GTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDT 440
C C G+L C+ T G C C+ G +CDRC G CRPC CN G D
Sbjct: 830 ACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFP--SCRPCVCN--GHADE 885
Query: 441 CDPRSGRC-PCKENVEGNLCDRCRPGTFNLQPHNPAG--CSSCFC 482
C+ +G C C+++ G C+RC G F+ P P G C C C
Sbjct: 886 CNTHTGACLGCRDHTGGEHCERCIAG-FHGDPRLPYGGQCRPCPC 929
Score = 90.5 bits (223), Expect = 1e-17
Identities = 63/176 (35%), Positives = 76/176 (43%), Gaps = 37/176 (21%)
Query: 270 RCKCN---GHASEC-GPDV------AGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAE 319
RC CN + +C PD +GQ C C N G C+RC P F W
Sbjct: 1037 RCTCNLLGTNPQQCPSPDQCHCDPSSGQ--CPCLPNVQGPSCDRCAPNF----W---NLT 1087
Query: 320 AAHECLPCNCS---GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHW-D 375
+ H C PC C R C G+CH CR G C CQE HW D
Sbjct: 1088 SGHGCQPCACHPSRARGPTCN---------EFTGQCH-CRAGFGGRTCSECQE--LHWGD 1135
Query: 376 PRMPCQPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPC 430
P + C CDC S G QC TG C+C+P V+G +CD+C GF + C PC
Sbjct: 1136 PGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFP-ACHPC 1190
Score = 75.1 bits (183), Expect = 5e-13
Identities = 57/197 (28%), Positives = 80/197 (40%), Gaps = 33/197 (16%)
Query: 675 CPTGYTGQFCESCAPGYKREMPQG-GPYASCVPCTCNQHGT-----CDPN--------TG 720
C G+ CE C P + R+ + A C C C+ G+ CD + +G
Sbjct: 377 CQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSG 436
Query: 721 ICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPC------PGQSACTTIPESREVVC 774
C C H G C++C GF+G + + C+ C C PG + C P S C
Sbjct: 437 QCRCKEHVVGTRCQQCRDGFFGLSISDRL-GCRRCQCNARGTVPGSTPCD--PNSGSCYC 493
Query: 775 THCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRC 834
GR C+ C G +G L G +PC C G +DP CD +G C C
Sbjct: 494 KRL---VTGRGCDRCLPGHWGLSHDLLG-CRPC-DCDVGGALDP----QCDEGTGQC-HC 543
Query: 835 LHNTTGDHCEHCQEGFY 851
+ G CE Q G++
Sbjct: 544 RQHMVGRRCEQVQPGYF 560
Score = 72.0 bits (175), Expect = 4e-12
Identities = 42/128 (32%), Positives = 51/128 (39%), Gaps = 11/128 (8%)
Query: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT------CDPNTGICVCSH 726
C C G C+ C G+ C C CN GT CDPN+G C C
Sbjct: 438 CRCKEHVVGTRCQQCRDGFFGLSISDR--LGCRRCQCNARGTVPGSTPCDPNSGSCYCKR 495
Query: 727 HTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRC 786
G C+RCLPG +G + C+PC C A + C HC GRRC
Sbjct: 496 LVTGRGCDRCLPGHWG--LSHDLLGCRPCDCDVGGALDPQCDEGTGQC-HCRQHMVGRRC 552
Query: 787 EVCDDGFF 794
E G+F
Sbjct: 553 EQVQPGYF 560
Score = 67.8 bits (164), Expect = 8e-11
Identities = 38/104 (36%), Positives = 47/104 (45%), Gaps = 8/104 (7%)
Query: 394 QCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDT-CDPRSGRCPCKE 452
QC + G K T C L +L G PC CNP GSL + C+P G+C CK
Sbjct: 748 QCHEEGLVPSK-TSPSEACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKP 806
Query: 453 NVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGH---SKVCASTA 493
V G CD C PG + P GC +C C S +C T+
Sbjct: 807 GVVGRRCDLCAPGYYGF---GPTGCQACQCSHEGALSSLCEKTS 847
Score = 48.9 bits (115), Expect = 4e-05
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Query: 945 QACDRCQLGFFGFSIKGCRACRCSPLGAASAQCH-ENGTCVCRPGFEGYKCDRCHDNFFL 1003
+AC + G C+C+P G+ S++C+ G C+C+PG G +CD C ++
Sbjct: 763 EACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYY- 821
Query: 1004 TADGTHCQQC 1013
T CQ C
Sbjct: 822 GFGPTGCQAC 831
Score = 48.5 bits (114), Expect = 5e-05
Identities = 96/366 (26%), Positives = 158/366 (43%), Gaps = 56/366 (15%)
Query: 1174 AATAWRAL-LASNTSYALLWNLLEG-----RVALETQRDLEDRYQEVQAA---QKALRTA 1224
AATA AL A +T L L EG RVA ET+R + Q QAA A R
Sbjct: 1446 AATADLALGRARHTQAELQRALAEGGSILSRVA-ETRRQASEAQQRAQAALDKANASRGQ 1504
Query: 1225 VAEVLPEAESVLATVQ----QVGADTAPYLALLASPGALPQKSRAEDLGLKAKALEKTVA 1280
V + E + ++ +V+ Q GAD + L + AE + A A+ + V
Sbjct: 1505 VEQANQELQELIQSVKDFLNQEGADPDSIEMVATRVLELSIPASAEQIQHLAGAIAERVR 1564
Query: 1281 SWQHMATEAARTLQTAAQATLRQTEPLTKLHQEARAALTQASSSVQAATVTVMGARTLLA 1340
S + ART+ +A +L Q+AR A + A Q A T+ A
Sbjct: 1565 SLADVDAILARTVGDVRRAE--------QLLQDARRARSWAEDEKQKA-------ETVQA 1609
Query: 1341 DLEGMKLQFPRPKDQAALQRKADSVSDRLLADTRKKTKQAERMLGNAAPLSSSAKKKGRE 1400
LE + Q + Q A++ +V+D DT + Q + + A SSA ++ R+
Sbjct: 1610 ALE--EAQRAQGIAQGAIR---GAVADT--RDTEQTLYQVQERMAGAERALSSAGERARQ 1662
Query: 1401 AEVL-----------------AKDSAKLAKALLRERKQAHRRASRLTSQT-QATLQQASQ 1442
+ L A+++A A+ +E +Q R QT +A ++ +Q
Sbjct: 1663 LDALLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQ 1722
Query: 1443 QVLASEARRQEL-EEAERVGAGLSEMEQQIRESRISLEKDIETLSELLARLGSLDTH-QA 1500
VLA++AR ++L +EA + + Q+++E + E++ L A+L L+ ++
Sbjct: 1723 GVLAAQARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARMRS 1782
Query: 1501 PAQALN 1506
QA+N
Sbjct: 1783 VLQAIN 1788
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 295 bits (754), Expect = 3e-79
Identities = 197/614 (32%), Positives = 282/614 (45%), Gaps = 95/614 (15%)
Query: 271 CKCNGHAS---ECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPC 327
C+C+ + C P+ GQ C CQ N G C RC P C PC
Sbjct: 1266 CECHPTGATGPHCSPE-GGQ--CPCQPNVIGRQCTRCATGHYGFP----------RCKPC 1312
Query: 328 NCSGR-SEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQ 386
+C R EE T G+C C T P CE C+ + + + P C+ C+C
Sbjct: 1313 SCGRRLCEEMT------------GQCR-CPPRTVRPQCEVCETHSFSFHPMAGCEGCNCS 1359
Query: 387 SAGSLHL---QCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD-TC 441
G++ +CD D+G C CKP +TG +CDRC GF+ E C PC CN G+ C
Sbjct: 1360 RRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPE--CVPCNCNRDGTEPGVC 1417
Query: 442 DPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVCASTAQFQVHHIL 501
DP +G C CKENVEG C+ CR G+F+L P N GC+SCFC+G + C S+ + + +
Sbjct: 1418 DPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFV- 1476
Query: 502 SDFHQGAEGWWARSVGGSEHPPQWSPNGVLLSPEDEE--------ELTAPEKFLGDQRFS 553
GW + + P ++P + + +E AP +LGD+ S
Sbjct: 1477 -----DMLGWHLETADRVDIPVSFNPGSNSMVADLQELPATIHSASWVAPTSYLGDKVSS 1531
Query: 554 YGQPLILTFRVP----PGDSPL---PVQLRLEGTGLALSLRHSSLSGPQDAGHPREVELR 606
YG LT++ PGD L ++L G +++ ++ P H R +
Sbjct: 1532 YGG--YLTYQAKSFGLPGDMVLLEKKPDVQLTGQHMSIIYEETNTPRPDRLHHGRVHVVE 1589
Query: 607 FHLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSPGPSPAGPVFLTEVRLTSARPGLSPP 666
+ + S P+ +L+ L +R++ G F RLT + GL
Sbjct: 1590 GNFRHASS--RAPVSREELMTVLSRLADVRIQ--------GLYFTETQRLTLSEVGLEEA 1639
Query: 667 --------ASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT-CDP 717
A VEIC+CP Y G C+ C+PGY R+ +G CVPC CN H C
Sbjct: 1640 SDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRD-HKGLYTGRCVPCNCNGHSNQCQD 1698
Query: 718 NTGICV-CSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTT--IPESREVVC 774
+GICV C H+T G CERC G+YGN G C+ CPCP ++ T + +V C
Sbjct: 1699 GSGICVNCQHNTAGEHCERCQEGYYGNAVHG---SCRACPCPHTNSFATGCVVNGGDVRC 1755
Query: 775 THCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCL-- 832
+ C G G +CE C G+FG+P G QP C C+ N +G+C PL+G C+
Sbjct: 1756 S-CKAGYTGTQCERCAPGYFGNPQKFGGSCQP---CSCNSN---GQLGSCHPLTGDCINQ 1808
Query: 833 RCLHNTTGDHCEHC 846
++ + C+ C
Sbjct: 1809 EPKDSSPAEECDDC 1822
Score = 261 bits (667), Expect = 4e-69
Identities = 165/532 (31%), Positives = 239/532 (44%), Gaps = 73/532 (13%)
Query: 10 LALLAPRAAGA-GMGACYDGAGRPQRCLPVFENAAFGRLAQASHTCGS--------PPED 60
L LL R A G A GA P + N A A+ TCG PE
Sbjct: 21 LLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPEL 80
Query: 61 FCPHVGAAGA--------GAHCQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGV 112
+C VG A G C C++ DP++ H + D WWQSP ++ G
Sbjct: 81 YCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAID----GSERWWQSPPLSSGT 136
Query: 113 QYPTSVNITLRLGKAYEITYVRLKFHTS-RPESFAIYKRSRADGPWEPYQFYSAS---CQ 168
QY VN+TL LG+ + + Y+ +KF S RP+ + + + + P+Q+++ S C
Sbjct: 137 QY-NRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCL 195
Query: 169 KTYGRPEGQYLRPGEDERVAFCTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEW 228
K +GR + +D C +E+S I PL G V S + GRP A NF S L+E+
Sbjct: 196 KEFGREANMAVTRDDD---VLCVTEYSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREF 252
Query: 229 VTSTELLISLDRLNTFGDDIF----KDPKVLQSYYYAVSDFSVGGRCKCNGHASECGPDV 284
+T + + R NT + +DP V + YYY++ D S+GG+C CNGHA C +
Sbjct: 253 TKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCVCNGHAEVCNINN 312
Query: 285 AGQL-ACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELF 343
+L C CQH+T G C+RC + R W E +HEC CNC G + C +D ++
Sbjct: 313 PEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVE 372
Query: 344 RSTGH---------GGRCHHCRDHTAGPHCERCQENFYH-----WDPRMPCQPCDCQSAG 389
R GG C +C+ +TAG +CE+C + +Y D C PC C
Sbjct: 373 RQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEH 432
Query: 390 SLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLS-------------------EGGCRPC 430
+ + +G C CKP G C++C G+++ G + C
Sbjct: 433 ADGCE-QGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGC 491
Query: 431 TCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
CN G L GRC C+ VEG CD CR G ++ C +C+C
Sbjct: 492 DCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI-----CQACWC 538
Score = 168 bits (426), Expect = 3e-41
Identities = 109/361 (30%), Positives = 156/361 (43%), Gaps = 62/361 (17%)
Query: 674 SCPTGYTGQFCESCAPGYKREMPQGGPYAS---CVPCTCN-QHGT-CDPNTGICVCSHHT 728
+C G CE CA GY R P G P + C+PC+C+ +H C+ +G C C +
Sbjct: 392 NCQHNTAGVNCEQCAKGYYR--PYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNF 449
Query: 729 EGPSCERCLPGFYGNPFAGQ---------------ADDCQPCPCPGQSACTTIPESREVV 773
G +CE+C G+Y PF + A D + C C + I ++
Sbjct: 450 HGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRC 509
Query: 774 CTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGN----CDPLSG 829
C PG G RC+ C GF+ P+ C C CS A+G+ C ++G
Sbjct: 510 L--CRPGVEGPRCDTCRSGFYSFPI--------CQACWCS------ALGSYQMPCSSVTG 553
Query: 830 HCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSC 889
C C TG C+ C G Y P + +C P G+++ + G C C
Sbjct: 554 QC-ECRPGVTGQRCDRCLSGAYDF-----PHCQGSSSACDPAGTINSNL------GYCQC 601
Query: 890 LPHVTARDCSRCYPGFFDLQPGR--GCRSCKCHPLG--SQEDQCHPKTGQCTCRPGVTGQ 945
HV CSRC +++L GC CKCH G S +C G C C+ V G
Sbjct: 602 KLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGD 661
Query: 946 ACDRCQLGFFGF---SIKGCRACRCSPLGAASAQCH-ENGTCVCRPGFEGYKCDRCHDNF 1001
+CD C+ G+F + GC+ C+C GA S+ C +G C CR G C R +N+
Sbjct: 662 SCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNY 721
Query: 1002 F 1002
+
Sbjct: 722 Y 722
Score = 165 bits (418), Expect = 3e-40
Identities = 116/386 (30%), Positives = 159/386 (41%), Gaps = 65/386 (16%)
Query: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYA---SCVPCTCNQHGT---CDPNT------- 719
C C G+ C+ C GY + + + C C C+ H + DP+
Sbjct: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
Query: 720 ---------GICV-CSHHTEGPSCERCLPGF---YGNPFAGQADDCQPCPCPGQSACTTI 766
G+C+ C H+T G +CE+C G+ YG P D C PC C + A
Sbjct: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVP-VDAPDGCIPCSCDPEHADGCE 437
Query: 767 PESREVVCTHCPPGQRGRRCEVCDDGFFGDP----LGLFGHPQPCHQCQCSGNV---DPN 819
S HC P G CE C G++ P + +F P + +G++ D N
Sbjct: 438 QGSGR---CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCN 494
Query: 820 AVG----NCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVS 875
G CD G CL C G C+ C+ GFY + C C C GS
Sbjct: 495 LEGVLPEICD-AHGRCL-CRPGVEGPRCDTCRSGFYSFPI-------CQACWCSALGSY- 544
Query: 876 EQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQ 935
QMPC VTGQC C P VT + C RC G +D +G S C P G+ + G
Sbjct: 545 -QMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-CDPAGT----INSNLGY 598
Query: 936 CTCRPGVTGQACDRCQLGFFGF---SIKGCRACRCSPLGAAS--AQCHE-NGTCVCRPGF 989
C C+ V G C RC+L ++ + GC C+C G S +C + +G C C+
Sbjct: 599 CQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHV 658
Query: 990 EGYKCDRCHDNFFLTADGTH--CQQC 1013
G CD C D +F + CQ C
Sbjct: 659 GGDSCDTCEDGYFALEKSNYFGCQGC 684
Score = 156 bits (395), Expect = 1e-37
Identities = 105/330 (31%), Positives = 136/330 (41%), Gaps = 54/330 (16%)
Query: 707 CTCNQHG-TCDPNTGI----CVCSHHTEGPSCERCLPGFYGNPFAG----QADDCQPCPC 757
C CN H C+ N C C HHT G +C+RC G+ + Q+ +C+ C C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
Query: 758 PGQSA-CTTIPESREV--------------VCTHCPPGQRGRRCEVCDDGFFGDPLGL-F 801
G ++ C P+ VC +C G CE C G++ P G+
Sbjct: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYR-PYGVPV 417
Query: 802 GHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPR--- 858
P C C C DP C+ SG C C N GD+CE C G+Y R
Sbjct: 418 DAPDGCIPCSC----DPEHADGCEQGSGRC-HCKPNFHGDNCEKCAIGYYNFPFCLRIPI 472
Query: 859 -----------PADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFD 907
A C C+ +G + E CD G+C C P V C C GF+
Sbjct: 473 FPVSTPSSEDPVAGDIKGCDCNLEGVLPEI--CD-AHGRCLCRPGVEGPRCDTCRSGFYS 529
Query: 908 LQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRC 967
C++C C LGS + C TGQC CRPGVTGQ CDRC G + F + C
Sbjct: 530 FPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSAC 586
Query: 968 SPLGAASAQCHENGTCVCRPGFEGYKCDRC 997
P G ++ G C C+ EG C RC
Sbjct: 587 DPAGTINSNL---GYCQCKLHVEGPTCSRC 613
Score = 130 bits (328), Expect = 8e-30
Identities = 91/311 (29%), Positives = 120/311 (38%), Gaps = 59/311 (18%)
Query: 673 CSCPTGYTGQFCESCAPGY-----------------KREMPQGGPYASCVPCTCNQHGT- 714
C C + G CE CA GY E P G C CN G
Sbjct: 443 CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKG---CDCNLEGVL 499
Query: 715 ---CDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPG----QSACTTIP 767
CD + G C+C EGP C+ C GFY P CQ C C Q C+++
Sbjct: 500 PEICDAH-GRCLCRPGVEGPRCDTCRSGFYSFPI------CQACWCSALGSYQMPCSSVT 552
Query: 768 ESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNV-DPNAVGNCDP 826
E C PG G+RC+ C G + P CQ S + DP G +
Sbjct: 553 GQCE-----CRPGVTGQRCDRCLSGAYDFP-----------HCQGSSSACDP--AGTINS 594
Query: 827 LSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQ 886
G+C +C + G C C+ ++ L C C CH G+VS C G
Sbjct: 595 NLGYC-QCKLHVEGPTCSRCKLLYWN--LDKENPSGCSECKCHKAGTVSGTGECRQGDGD 651
Query: 887 CSCLPHVTARDCSRCYPGFFDLQPGR--GCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTG 944
C C HV C C G+F L+ GC+ C+C G+ C +G C CR V G
Sbjct: 652 CHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVG 711
Query: 945 QACDRCQLGFF 955
+ C R + ++
Sbjct: 712 KVCQRPENNYY 722
Score = 127 bits (319), Expect = 8e-29
Identities = 71/216 (32%), Positives = 94/216 (43%), Gaps = 27/216 (12%)
Query: 806 PCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMP 865
PC +C +G P+ C P G C C N G C C G YG +C P
Sbjct: 1265 PC-ECHPTGATGPH----CSPEGGQC-PCQPNVIGRQCTRCATGHYGFP-------RCKP 1311
Query: 866 CSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQ 925
CSC + C+ +TGQC C P C C F P GC C C G+
Sbjct: 1312 CSCG-------RRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTI 1364
Query: 926 E---DQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHEN-G 981
E +C +GQC C+P +TG+ CDRC GF+ F C C C+ G C G
Sbjct: 1365 EAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP--ECVPCNCNRDGTEPGVCDPGTG 1422
Query: 982 TCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCY 1017
C+C+ EG +C+ C + F D + + C SC+
Sbjct: 1423 ACLCKENVEGTECNVCREGSF-HLDPANLKGCTSCF 1457
Score = 126 bits (317), Expect = 1e-28
Identities = 83/239 (34%), Positives = 106/239 (44%), Gaps = 41/239 (17%)
Query: 701 YASCVPCTCNQHGT----CDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCP 756
+ +PC C+ G C P G C C + G C RC G YG P C+PC
Sbjct: 1260 HKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP------RCKPCS 1313
Query: 757 CPGQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQP-CHQCQCS-- 813
C G+ C E C CPP +CEVC+ F HP C C CS
Sbjct: 1314 C-GRRLC----EEMTGQC-RCPPRTVRPQCEVCETHSFSF------HPMAGCEGCNCSRR 1361
Query: 814 GNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGS 873
G ++ A+ CD SG C RC TG C+ C GFY +C+PC+C+ G+
Sbjct: 1362 GTIEA-AMPECDRDSGQC-RCKPRITGRQCDRCASGFYRFP-------ECVPCNCNRDGT 1412
Query: 874 VSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPG--RGCRSCKCHPLGSQEDQCH 930
E CDP TG C C +V +C+ C G F L P +GC SC C + +QCH
Sbjct: 1413 --EPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGV---NNQCH 1466
Score = 125 bits (313), Expect = 4e-28
Identities = 83/286 (29%), Positives = 112/286 (39%), Gaps = 80/286 (27%)
Query: 271 CKCNGHASEC--GPDV--------------AGQLACRCQHNTTGTDCERC---------- 304
C C+GHAS C PDV G + CQHNT G +CE+C
Sbjct: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGV 415
Query: 305 --------LPFFQDRPWARGTAEAAHEC-----------------------------LPC 327
+P D A G + + C P
Sbjct: 416 PVDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPV 475
Query: 328 NCSGRSE---------ECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRM 378
+ + +C + L GRC CR GP C+ C+ FY +
Sbjct: 476 STPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFYSFPI-- 532
Query: 379 PCQPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGS 437
CQ C C + GS + C TG C C+P VTG +CDRCL G + C+PAG+
Sbjct: 533 -CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGT 591
Query: 438 LDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCY 483
+++ G C CK +VEG C RC+ +NL NP+GCS C C+
Sbjct: 592 INS---NLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCH 634
Score = 119 bits (298), Expect = 2e-26
Identities = 72/233 (30%), Positives = 100/233 (42%), Gaps = 35/233 (15%)
Query: 754 PCPC--PGQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQ 811
PC C G + PE + C P GR+C C G +G P C C
Sbjct: 1265 PCECHPTGATGPHCSPEGGQCPCQ---PNVIGRQCTRCATGHYGFPR--------CKPCS 1313
Query: 812 CSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQ 871
C + C+ ++G C RC T CE C+ + P C C+C +
Sbjct: 1314 CGRRL-------CEEMTGQC-RCPPRTVRPQCEVCETHSFSF----HPMAGCEGCNCSRR 1361
Query: 872 GSVSEQMP-CDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCH 930
G++ MP CD +GQC C P +T R C RC GF+ C C C+ G++ C
Sbjct: 1362 GTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPE---CVPCNCNRDGTEPGVCD 1418
Query: 931 PKTGQCTCRPGVTGQACDRCQLGFFGF---SIKGCRACRCSPLGAASAQCHEN 980
P TG C C+ V G C+ C+ G F ++KGC +C C + QCH +
Sbjct: 1419 PGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCF---GVNNQCHSS 1468
Score = 115 bits (288), Expect = 3e-25
Identities = 62/179 (34%), Positives = 83/179 (46%), Gaps = 17/179 (9%)
Query: 777 CPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLH 836
CPP G C+ C G++ D GL+ C C C+G+ + C SG C+ C H
Sbjct: 1656 CPPAYAGDSCQGCSPGYYRDHKGLY--TGRCVPCNCNGHSN-----QCQDGSGICVNCQH 1708
Query: 837 NTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTAR 896
NT G+HCE CQEG+YG+A+ C C C S + + +CSC T
Sbjct: 1709 NTAGEHCERCQEGYYGNAV----HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 1764
Query: 897 DCSRCYPGFF--DLQPGRGCRSCKCHPLGSQEDQCHPKTGQC---TCRPGVTGQACDRC 950
C RC PG+F + G C+ C C+ G Q CHP TG C + + CD C
Sbjct: 1765 QCERCAPGYFGNPQKFGGSCQPCSCNSNG-QLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 103 bits (258), Expect = 1e-21
Identities = 53/152 (34%), Positives = 69/152 (45%), Gaps = 15/152 (9%)
Query: 864 MPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLG 923
+PC CHP G+ C P GQC C P+V R C+RC G + C+ C C
Sbjct: 1264 LPCECHPTGATGPH--CSPEGGQCPCQPNVIGRQCTRCATGHYGFPR---CKPCSCG--- 1315
Query: 924 SQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFS-IKGCRACRCSPLG---AASAQC-H 978
C TGQC C P C+ C+ F F + GC C CS G AA +C
Sbjct: 1316 --RRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDR 1373
Query: 979 ENGTCVCRPGFEGYKCDRCHDNFFLTADGTHC 1010
++G C C+P G +CDRC F+ + C
Sbjct: 1374 DSGQCRCKPRITGRQCDRCASGFYRFPECVPC 1405
Score = 100 bits (248), Expect = 1e-20
Identities = 142/676 (21%), Positives = 249/676 (36%), Gaps = 109/676 (16%)
Query: 840 GDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARD-C 898
GD C+ C G+Y +C+PC+C+ + C +G C H TA + C
Sbjct: 1662 GDSCQGCSPGYYRDHKGLYTG-RCVPCNCNGHSN-----QCQDGSGICVNCQHNTAGEHC 1715
Query: 899 SRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTG--QCTCRPGVTGQACDRCQLGFFG 956
RC G++ CR+C C S C G +C+C+ G TG C+RC G+FG
Sbjct: 1716 ERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFG 1775
Query: 957 FSIK---GCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQ 1012
K C+ C C+ G + CH G C+ + + + C D
Sbjct: 1776 NPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDD------------- 1821
Query: 1013 CPSCYALVKEEAAKLKARLTLTEGWLQGSDCGSPWGPLDILLGEAPRGDVYQGHHLLPGA 1072
C SC + + A + +L L + LQG A
Sbjct: 1822 CDSCVMTLLNDLATMGEQLRLVKSQLQGL-----------------------------SA 1852
Query: 1073 REAFLEQMMSLEGAVKAAREQLQRLNKGARCAQAGS--QKTCTQLADLEAVLESSEEEIL 1130
LEQM +E K R QL LN + + GS + +L DL E+ +E+
Sbjct: 1853 SAGLLEQMRHMETQAKDLRNQL--LNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQ 1910
Query: 1131 HAAAILASLEIPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRALLASNTSYAL 1190
+ +L +Q K L + + + R+ +I+ T + ++
Sbjct: 1911 VNSRKAQTLNNNVNRATQSAK--ELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSR 1968
Query: 1191 LWNLLEGRVALETQRDLEDRYQEVQAAQKALRTAVAEVLPEAESVLATVQQVGADTAPYL 1250
W + + R+ +E +A ++ + + + T Q+ L
Sbjct: 1969 EWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRI--------RTWQKTHQGENNGL 2020
Query: 1251 ALLASPGALPQKSRAEDLGLKAKALEKTVASWQHMATEAARTLQTAAQATLRQTEPLTKL 1310
A +++ DL +A + A+ A + + A A RQ + + L
Sbjct: 2021 ANSIRDSLNEYEAKLSDL----RARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSL 2076
Query: 1311 HQEARAALTQASSSVQAATVTVMGARTLLADLEGMKLQFPRPKDQAALQRKADSVSDRL- 1369
+ LT A SS+ + + K Q K A+L +SD++
Sbjct: 2077 QSDFTKYLTTADSSLLQTNIALQLME---------KSQKEYEKLAASLNEARQELSDKVR 2127
Query: 1370 -LADTRKKTKQAERMLGNAAPLSSSAKK--------KGREAEVLAKDSAKLAKALLRERK 1420
L+ + KT E +A L AK+ G E A D+A + +L K
Sbjct: 2128 ELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIK 2187
Query: 1421 QAHRRASRLTSQTQATLQ--------------QASQQVLASEARRQELEEAERVGAGLSE 1466
A A+R S +++ LQ ++ L +EA+ + + + V L+
Sbjct: 2188 AAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNN 2247
Query: 1467 MEQQIRESRISLEKDI 1482
++Q + + ++++K++
Sbjct: 2248 LQQTL--NIVTVQKEV 2261
Score = 98.6 bits (244), Expect = 4e-20
Identities = 68/249 (27%), Positives = 99/249 (39%), Gaps = 54/249 (21%)
Query: 809 QCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAP---RPADKCMP 865
QC C+G+ + + N + L C C H+T G+ C+ C G+ P + +C
Sbjct: 298 QCVCNGHAEVCNINNPEKLF-RC-ECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEA 355
Query: 866 CSCHPQGSVS------EQMPCDPVT-------GQCSCLPHVTAR-DCSRCYPGFF----- 906
C+CH S E+ T G C H TA +C +C G++
Sbjct: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGV 415
Query: 907 DLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGF--------- 957
+ GC C C P D C +G+C C+P G C++C +G++ F
Sbjct: 416 PVDAPDGCIPCSCDP--EHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIF 473
Query: 958 -------------SIKGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLT 1004
IKGC C+ G C +G C+CRPG EG +CD C F+
Sbjct: 474 PVSTPSSEDPVAGDIKGCD---CNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFY-- 528
Query: 1005 ADGTHCQQC 1013
CQ C
Sbjct: 529 -SFPICQAC 536
Score = 98.2 bits (243), Expect = 6e-20
Identities = 68/208 (32%), Positives = 96/208 (46%), Gaps = 32/208 (15%)
Query: 265 FSVGGRCKCNGHASECGP--DVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAH 322
F + C C+ S P V GQ C C+ TG C+RCL D P +G++ A
Sbjct: 530 FPICQACWCSALGSYQMPCSSVTGQ--CECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-- 585
Query: 323 ECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--C 380
C+ +G T + L G C C+ H GP C RC+ +++ D P C
Sbjct: 586 ----CDPAG-----TINSNL-------GYC-QCKLHVEGPTCSRCKLLYWNLDKENPSGC 628
Query: 381 QPCDCQSAGSLH--LQC-DDTGTCACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNP 434
C C AG++ +C G C CK V G CD C G+ +L + GC+ C C+
Sbjct: 629 SECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDI 688
Query: 435 AGSLDT-CDPRSGRCPCKENVEGNLCDR 461
G+L + C SG C C+E+V G +C R
Sbjct: 689 GGALSSMCSGPSGVCQCREHVVGKVCQR 716
Score = 82.4 bits (202), Expect = 3e-15
Identities = 55/189 (29%), Positives = 74/189 (39%), Gaps = 15/189 (7%)
Query: 665 PPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVC 724
P +S C C G TGQ C+ C G P+ C+ GT + N G C C
Sbjct: 547 PCSSVTGQCECRPGVTGQRCDRCLSG-----AYDFPHCQGSSSACDPAGTINSNLGYCQC 601
Query: 725 SHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESRE-VVCTHCPPGQRG 783
H EGP+C RC Y N C C C + E R+ HC G
Sbjct: 602 KLHVEGPTCSRC-KLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGG 660
Query: 784 RRCEVCDDGFFG-DPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDH 842
C+ C+DG+F + FG C CQC ++ C SG C +C + G
Sbjct: 661 DSCDTCEDGYFALEKSNYFG----CQGCQC--DIGGALSSMCSGPSGVC-QCREHVVGKV 713
Query: 843 CEHCQEGFY 851
C+ + +Y
Sbjct: 714 CQRPENNYY 722
Score = 54.3 bits (129), Expect = 9e-07
Identities = 22/58 (37%), Positives = 27/58 (46%), Gaps = 1/58 (1%)
Query: 426 GCRPCTCNPAGSLDT-CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
G PC C+P G+ C P G+CPC+ NV G C RC G + P C C
Sbjct: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLC 1319
Score = 43.9 bits (102), Expect = 0.001
Identities = 26/85 (30%), Positives = 32/85 (37%), Gaps = 5/85 (5%)
Query: 940 PGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCH-ENGTCVCRPGFEGYKCDRCH 998
P + C F KG C C P GA C E G C C+P G +C RC
Sbjct: 1241 PQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCA 1300
Query: 999 DNFFLTADGTHCQQCPSCYALVKEE 1023
+ C+ C SC + EE
Sbjct: 1301 TGHY---GFPRCKPC-SCGRRLCEE 1321
Score = 43.5 bits (101), Expect = 0.002
Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 19/95 (20%)
Query: 405 PTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSG----RCPCKENVEGNLCD 460
PTVT R +S GG C CN G + C+ + RC C+ + G CD
Sbjct: 280 PTVTR----RYYYSIKDISIGG--QCVCN--GHAEVCNINNPEKLFRCECQHHTCGETCD 331
Query: 461 RCRPGTFNLQPHNPAG------CSSCFCYGHSKVC 489
RC G +N + PA C +C C+GH+ C
Sbjct: 332 RCCTG-YNQRRWRPAAWEQSHECEACNCHGHASNC 365
Score = 38.5 bits (88), Expect = 0.052
Identities = 31/110 (28%), Positives = 43/110 (39%), Gaps = 20/110 (18%)
Query: 271 CKCN--GHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCN 328
CKC+ G S G G C C+ + G C+ C +D +A + C C
Sbjct: 631 CKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTC----EDGYFALEKSNY-FGCQGCQ 685
Query: 329 CS---GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWD 375
C S C+ G G C CR+H G C+R + N+Y D
Sbjct: 686 CDIGGALSSMCS---------GPSGVCQ-CREHVVGKVCQRPENNYYFPD 725
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 295 bits (754), Expect = 3e-79
Identities = 197/614 (32%), Positives = 282/614 (45%), Gaps = 95/614 (15%)
Query: 271 CKCNGHAS---ECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPC 327
C+C+ + C P+ GQ C CQ N G C RC P C PC
Sbjct: 1266 CECHPTGATGPHCSPE-GGQ--CPCQPNVIGRQCTRCATGHYGFP----------RCKPC 1312
Query: 328 NCSGR-SEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQ 386
+C R EE T G+C C T P CE C+ + + + P C+ C+C
Sbjct: 1313 SCGRRLCEEMT------------GQCR-CPPRTVRPQCEVCETHSFSFHPMAGCEGCNCS 1359
Query: 387 SAGSLHL---QCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD-TC 441
G++ +CD D+G C CKP +TG +CDRC GF+ E C PC CN G+ C
Sbjct: 1360 RRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPE--CVPCNCNRDGTEPGVC 1417
Query: 442 DPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVCASTAQFQVHHIL 501
DP +G C CKENVEG C+ CR G+F+L P N GC+SCFC+G + C S+ + + +
Sbjct: 1418 DPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFV- 1476
Query: 502 SDFHQGAEGWWARSVGGSEHPPQWSPNGVLLSPEDEE--------ELTAPEKFLGDQRFS 553
GW + + P ++P + + +E AP +LGD+ S
Sbjct: 1477 -----DMLGWHLETADRVDIPVSFNPGSNSMVADLQELPATIHSASWVAPTSYLGDKVSS 1531
Query: 554 YGQPLILTFRVP----PGDSPL---PVQLRLEGTGLALSLRHSSLSGPQDAGHPREVELR 606
YG LT++ PGD L ++L G +++ ++ P H R +
Sbjct: 1532 YGG--YLTYQAKSFGLPGDMVLLEKKPDVQLTGQHMSIIYEETNTPRPDRLHHGRVHVVE 1589
Query: 607 FHLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSPGPSPAGPVFLTEVRLTSARPGLSPP 666
+ + S P+ +L+ L +R++ G F RLT + GL
Sbjct: 1590 GNFRHASS--RAPVSREELMTVLSRLADVRIQ--------GLYFTETQRLTLSEVGLEEA 1639
Query: 667 --------ASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT-CDP 717
A VEIC+CP Y G C+ C+PGY R+ +G CVPC CN H C
Sbjct: 1640 SDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRD-HKGLYTGRCVPCNCNGHSNQCQD 1698
Query: 718 NTGICV-CSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTT--IPESREVVC 774
+GICV C H+T G CERC G+YGN G C+ CPCP ++ T + +V C
Sbjct: 1699 GSGICVNCQHNTAGEHCERCQEGYYGNAVHG---SCRACPCPHTNSFATGCVVNGGDVRC 1755
Query: 775 THCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCL-- 832
+ C G G +CE C G+FG+P G QP C C+ N +G+C PL+G C+
Sbjct: 1756 S-CKAGYTGTQCERCAPGYFGNPQKFGGSCQP---CSCNSN---GQLGSCHPLTGDCINQ 1808
Query: 833 RCLHNTTGDHCEHC 846
++ + C+ C
Sbjct: 1809 EPKDSSPAEECDDC 1822
Score = 261 bits (667), Expect = 4e-69
Identities = 165/532 (31%), Positives = 239/532 (44%), Gaps = 73/532 (13%)
Query: 10 LALLAPRAAGA-GMGACYDGAGRPQRCLPVFENAAFGRLAQASHTCGS--------PPED 60
L LL R A G A GA P + N A A+ TCG PE
Sbjct: 21 LLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPEL 80
Query: 61 FCPHVGAAGA--------GAHCQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGV 112
+C VG A G C C++ DP++ H + D WWQSP ++ G
Sbjct: 81 YCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAID----GSERWWQSPPLSSGT 136
Query: 113 QYPTSVNITLRLGKAYEITYVRLKFHTS-RPESFAIYKRSRADGPWEPYQFYSAS---CQ 168
QY VN+TL LG+ + + Y+ +KF S RP+ + + + + P+Q+++ S C
Sbjct: 137 QY-NRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCL 195
Query: 169 KTYGRPEGQYLRPGEDERVAFCTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEW 228
K +GR + +D C +E+S I PL G V S + GRP A NF S L+E+
Sbjct: 196 KEFGREANMAVTRDDD---VLCVTEYSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREF 252
Query: 229 VTSTELLISLDRLNTFGDDIF----KDPKVLQSYYYAVSDFSVGGRCKCNGHASECGPDV 284
+T + + R NT + +DP V + YYY++ D S+GG+C CNGHA C +
Sbjct: 253 TKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCVCNGHAEVCNINN 312
Query: 285 AGQL-ACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELF 343
+L C CQH+T G C+RC + R W E +HEC CNC G + C +D ++
Sbjct: 313 PEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVE 372
Query: 344 RSTGH---------GGRCHHCRDHTAGPHCERCQENFYH-----WDPRMPCQPCDCQSAG 389
R GG C +C+ +TAG +CE+C + +Y D C PC C
Sbjct: 373 RQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEH 432
Query: 390 SLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLS-------------------EGGCRPC 430
+ + +G C CKP G C++C G+++ G + C
Sbjct: 433 ADGCE-QGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGC 491
Query: 431 TCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
CN G L GRC C+ VEG CD CR G ++ C +C+C
Sbjct: 492 DCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI-----CQACWC 538
Score = 168 bits (426), Expect = 3e-41
Identities = 109/361 (30%), Positives = 156/361 (43%), Gaps = 62/361 (17%)
Query: 674 SCPTGYTGQFCESCAPGYKREMPQGGPYAS---CVPCTCN-QHGT-CDPNTGICVCSHHT 728
+C G CE CA GY R P G P + C+PC+C+ +H C+ +G C C +
Sbjct: 392 NCQHNTAGVNCEQCAKGYYR--PYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNF 449
Query: 729 EGPSCERCLPGFYGNPFAGQ---------------ADDCQPCPCPGQSACTTIPESREVV 773
G +CE+C G+Y PF + A D + C C + I ++
Sbjct: 450 HGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRC 509
Query: 774 CTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGN----CDPLSG 829
C PG G RC+ C GF+ P+ C C CS A+G+ C ++G
Sbjct: 510 L--CRPGVEGPRCDTCRSGFYSFPI--------CQACWCS------ALGSYQMPCSSVTG 553
Query: 830 HCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSC 889
C C TG C+ C G Y P + +C P G+++ + G C C
Sbjct: 554 QC-ECRPGVTGQRCDRCLSGAYDF-----PHCQGSSSACDPAGTINSNL------GYCQC 601
Query: 890 LPHVTARDCSRCYPGFFDLQPGR--GCRSCKCHPLG--SQEDQCHPKTGQCTCRPGVTGQ 945
HV CSRC +++L GC CKCH G S +C G C C+ V G
Sbjct: 602 KLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGD 661
Query: 946 ACDRCQLGFFGF---SIKGCRACRCSPLGAASAQCH-ENGTCVCRPGFEGYKCDRCHDNF 1001
+CD C+ G+F + GC+ C+C GA S+ C +G C CR G C R +N+
Sbjct: 662 SCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNY 721
Query: 1002 F 1002
+
Sbjct: 722 Y 722
Score = 165 bits (418), Expect = 3e-40
Identities = 116/386 (30%), Positives = 159/386 (41%), Gaps = 65/386 (16%)
Query: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYA---SCVPCTCNQHGT---CDPNT------- 719
C C G+ C+ C GY + + + C C C+ H + DP+
Sbjct: 319 CECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASL 378
Query: 720 ---------GICV-CSHHTEGPSCERCLPGF---YGNPFAGQADDCQPCPCPGQSACTTI 766
G+C+ C H+T G +CE+C G+ YG P D C PC C + A
Sbjct: 379 NTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVP-VDAPDGCIPCSCDPEHADGCE 437
Query: 767 PESREVVCTHCPPGQRGRRCEVCDDGFFGDP----LGLFGHPQPCHQCQCSGNV---DPN 819
S HC P G CE C G++ P + +F P + +G++ D N
Sbjct: 438 QGSGR---CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCN 494
Query: 820 AVG----NCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVS 875
G CD G CL C G C+ C+ GFY + C C C GS
Sbjct: 495 LEGVLPEICD-AHGRCL-CRPGVEGPRCDTCRSGFYSFPI-------CQACWCSALGSY- 544
Query: 876 EQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQ 935
QMPC VTGQC C P VT + C RC G +D +G S C P G+ + G
Sbjct: 545 -QMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-CDPAGT----INSNLGY 598
Query: 936 CTCRPGVTGQACDRCQLGFFGF---SIKGCRACRCSPLGAAS--AQCHE-NGTCVCRPGF 989
C C+ V G C RC+L ++ + GC C+C G S +C + +G C C+
Sbjct: 599 CQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHV 658
Query: 990 EGYKCDRCHDNFFLTADGTH--CQQC 1013
G CD C D +F + CQ C
Sbjct: 659 GGDSCDTCEDGYFALEKSNYFGCQGC 684
Score = 156 bits (395), Expect = 1e-37
Identities = 105/330 (31%), Positives = 136/330 (41%), Gaps = 54/330 (16%)
Query: 707 CTCNQHG-TCDPNTGI----CVCSHHTEGPSCERCLPGFYGNPFAG----QADDCQPCPC 757
C CN H C+ N C C HHT G +C+RC G+ + Q+ +C+ C C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
Query: 758 PGQSA-CTTIPESREV--------------VCTHCPPGQRGRRCEVCDDGFFGDPLGL-F 801
G ++ C P+ VC +C G CE C G++ P G+
Sbjct: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYR-PYGVPV 417
Query: 802 GHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPR--- 858
P C C C DP C+ SG C C N GD+CE C G+Y R
Sbjct: 418 DAPDGCIPCSC----DPEHADGCEQGSGRC-HCKPNFHGDNCEKCAIGYYNFPFCLRIPI 472
Query: 859 -----------PADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFD 907
A C C+ +G + E CD G+C C P V C C GF+
Sbjct: 473 FPVSTPSSEDPVAGDIKGCDCNLEGVLPEI--CD-AHGRCLCRPGVEGPRCDTCRSGFYS 529
Query: 908 LQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRC 967
C++C C LGS + C TGQC CRPGVTGQ CDRC G + F + C
Sbjct: 530 FPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSAC 586
Query: 968 SPLGAASAQCHENGTCVCRPGFEGYKCDRC 997
P G ++ G C C+ EG C RC
Sbjct: 587 DPAGTINSNL---GYCQCKLHVEGPTCSRC 613
Score = 130 bits (328), Expect = 8e-30
Identities = 91/311 (29%), Positives = 120/311 (38%), Gaps = 59/311 (18%)
Query: 673 CSCPTGYTGQFCESCAPGY-----------------KREMPQGGPYASCVPCTCNQHGT- 714
C C + G CE CA GY E P G C CN G
Sbjct: 443 CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKG---CDCNLEGVL 499
Query: 715 ---CDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPG----QSACTTIP 767
CD + G C+C EGP C+ C GFY P CQ C C Q C+++
Sbjct: 500 PEICDAH-GRCLCRPGVEGPRCDTCRSGFYSFPI------CQACWCSALGSYQMPCSSVT 552
Query: 768 ESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNV-DPNAVGNCDP 826
E C PG G+RC+ C G + P CQ S + DP G +
Sbjct: 553 GQCE-----CRPGVTGQRCDRCLSGAYDFP-----------HCQGSSSACDP--AGTINS 594
Query: 827 LSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQ 886
G+C +C + G C C+ ++ L C C CH G+VS C G
Sbjct: 595 NLGYC-QCKLHVEGPTCSRCKLLYWN--LDKENPSGCSECKCHKAGTVSGTGECRQGDGD 651
Query: 887 CSCLPHVTARDCSRCYPGFFDLQPGR--GCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTG 944
C C HV C C G+F L+ GC+ C+C G+ C +G C CR V G
Sbjct: 652 CHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVG 711
Query: 945 QACDRCQLGFF 955
+ C R + ++
Sbjct: 712 KVCQRPENNYY 722
Score = 127 bits (319), Expect = 8e-29
Identities = 71/216 (32%), Positives = 94/216 (43%), Gaps = 27/216 (12%)
Query: 806 PCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMP 865
PC +C +G P+ C P G C C N G C C G YG +C P
Sbjct: 1265 PC-ECHPTGATGPH----CSPEGGQC-PCQPNVIGRQCTRCATGHYGFP-------RCKP 1311
Query: 866 CSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQ 925
CSC + C+ +TGQC C P C C F P GC C C G+
Sbjct: 1312 CSCG-------RRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTI 1364
Query: 926 E---DQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHEN-G 981
E +C +GQC C+P +TG+ CDRC GF+ F C C C+ G C G
Sbjct: 1365 EAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP--ECVPCNCNRDGTEPGVCDPGTG 1422
Query: 982 TCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCY 1017
C+C+ EG +C+ C + F D + + C SC+
Sbjct: 1423 ACLCKENVEGTECNVCREGSF-HLDPANLKGCTSCF 1457
Score = 126 bits (317), Expect = 1e-28
Identities = 83/239 (34%), Positives = 106/239 (44%), Gaps = 41/239 (17%)
Query: 701 YASCVPCTCNQHGT----CDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCP 756
+ +PC C+ G C P G C C + G C RC G YG P C+PC
Sbjct: 1260 HKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP------RCKPCS 1313
Query: 757 CPGQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQP-CHQCQCS-- 813
C G+ C E C CPP +CEVC+ F HP C C CS
Sbjct: 1314 C-GRRLC----EEMTGQC-RCPPRTVRPQCEVCETHSFSF------HPMAGCEGCNCSRR 1361
Query: 814 GNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGS 873
G ++ A+ CD SG C RC TG C+ C GFY +C+PC+C+ G+
Sbjct: 1362 GTIEA-AMPECDRDSGQC-RCKPRITGRQCDRCASGFYRFP-------ECVPCNCNRDGT 1412
Query: 874 VSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPG--RGCRSCKCHPLGSQEDQCH 930
E CDP TG C C +V +C+ C G F L P +GC SC C + +QCH
Sbjct: 1413 --EPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCFGV---NNQCH 1466
Score = 125 bits (313), Expect = 4e-28
Identities = 83/286 (29%), Positives = 112/286 (39%), Gaps = 80/286 (27%)
Query: 271 CKCNGHASEC--GPDV--------------AGQLACRCQHNTTGTDCERC---------- 304
C C+GHAS C PDV G + CQHNT G +CE+C
Sbjct: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGV 415
Query: 305 --------LPFFQDRPWARGTAEAAHEC-----------------------------LPC 327
+P D A G + + C P
Sbjct: 416 PVDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPV 475
Query: 328 NCSGRSE---------ECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRM 378
+ + +C + L GRC CR GP C+ C+ FY +
Sbjct: 476 STPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFYSFPI-- 532
Query: 379 PCQPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGS 437
CQ C C + GS + C TG C C+P VTG +CDRCL G + C+PAG+
Sbjct: 533 -CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGT 591
Query: 438 LDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCY 483
+++ G C CK +VEG C RC+ +NL NP+GCS C C+
Sbjct: 592 INS---NLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCH 634
Score = 119 bits (298), Expect = 2e-26
Identities = 72/233 (30%), Positives = 100/233 (42%), Gaps = 35/233 (15%)
Query: 754 PCPC--PGQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQ 811
PC C G + PE + C P GR+C C G +G P C C
Sbjct: 1265 PCECHPTGATGPHCSPEGGQCPCQ---PNVIGRQCTRCATGHYGFPR--------CKPCS 1313
Query: 812 CSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQ 871
C + C+ ++G C RC T CE C+ + P C C+C +
Sbjct: 1314 CGRRL-------CEEMTGQC-RCPPRTVRPQCEVCETHSFSF----HPMAGCEGCNCSRR 1361
Query: 872 GSVSEQMP-CDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCH 930
G++ MP CD +GQC C P +T R C RC GF+ C C C+ G++ C
Sbjct: 1362 GTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPE---CVPCNCNRDGTEPGVCD 1418
Query: 931 PKTGQCTCRPGVTGQACDRCQLGFFGF---SIKGCRACRCSPLGAASAQCHEN 980
P TG C C+ V G C+ C+ G F ++KGC +C C + QCH +
Sbjct: 1419 PGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFCF---GVNNQCHSS 1468
Score = 115 bits (288), Expect = 3e-25
Identities = 62/179 (34%), Positives = 83/179 (46%), Gaps = 17/179 (9%)
Query: 777 CPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLH 836
CPP G C+ C G++ D GL+ C C C+G+ + C SG C+ C H
Sbjct: 1656 CPPAYAGDSCQGCSPGYYRDHKGLY--TGRCVPCNCNGHSN-----QCQDGSGICVNCQH 1708
Query: 837 NTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTAR 896
NT G+HCE CQEG+YG+A+ C C C S + + +CSC T
Sbjct: 1709 NTAGEHCERCQEGYYGNAV----HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 1764
Query: 897 DCSRCYPGFF--DLQPGRGCRSCKCHPLGSQEDQCHPKTGQC---TCRPGVTGQACDRC 950
C RC PG+F + G C+ C C+ G Q CHP TG C + + CD C
Sbjct: 1765 QCERCAPGYFGNPQKFGGSCQPCSCNSNG-QLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 103 bits (258), Expect = 1e-21
Identities = 53/152 (34%), Positives = 69/152 (45%), Gaps = 15/152 (9%)
Query: 864 MPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLG 923
+PC CHP G+ C P GQC C P+V R C+RC G + C+ C C
Sbjct: 1264 LPCECHPTGATGPH--CSPEGGQCPCQPNVIGRQCTRCATGHYGFPR---CKPCSCG--- 1315
Query: 924 SQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFS-IKGCRACRCSPLG---AASAQC-H 978
C TGQC C P C+ C+ F F + GC C CS G AA +C
Sbjct: 1316 --RRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDR 1373
Query: 979 ENGTCVCRPGFEGYKCDRCHDNFFLTADGTHC 1010
++G C C+P G +CDRC F+ + C
Sbjct: 1374 DSGQCRCKPRITGRQCDRCASGFYRFPECVPC 1405
Score = 98.6 bits (244), Expect = 4e-20
Identities = 68/249 (27%), Positives = 99/249 (39%), Gaps = 54/249 (21%)
Query: 809 QCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAP---RPADKCMP 865
QC C+G+ + + N + L C C H+T G+ C+ C G+ P + +C
Sbjct: 298 QCVCNGHAEVCNINNPEKLF-RC-ECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEA 355
Query: 866 CSCHPQGSVS------EQMPCDPVT-------GQCSCLPHVTAR-DCSRCYPGFF----- 906
C+CH S E+ T G C H TA +C +C G++
Sbjct: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGV 415
Query: 907 DLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGF--------- 957
+ GC C C P D C +G+C C+P G C++C +G++ F
Sbjct: 416 PVDAPDGCIPCSCDP--EHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIF 473
Query: 958 -------------SIKGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLT 1004
IKGC C+ G C +G C+CRPG EG +CD C F+
Sbjct: 474 PVSTPSSEDPVAGDIKGCD---CNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFY-- 528
Query: 1005 ADGTHCQQC 1013
CQ C
Sbjct: 529 -SFPICQAC 536
Score = 98.2 bits (243), Expect = 6e-20
Identities = 68/208 (32%), Positives = 96/208 (46%), Gaps = 32/208 (15%)
Query: 265 FSVGGRCKCNGHASECGP--DVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAH 322
F + C C+ S P V GQ C C+ TG C+RCL D P +G++ A
Sbjct: 530 FPICQACWCSALGSYQMPCSSVTGQ--CECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-- 585
Query: 323 ECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--C 380
C+ +G T + L G C C+ H GP C RC+ +++ D P C
Sbjct: 586 ----CDPAG-----TINSNL-------GYC-QCKLHVEGPTCSRCKLLYWNLDKENPSGC 628
Query: 381 QPCDCQSAGSLH--LQC-DDTGTCACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNP 434
C C AG++ +C G C CK V G CD C G+ +L + GC+ C C+
Sbjct: 629 SECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDI 688
Query: 435 AGSLDT-CDPRSGRCPCKENVEGNLCDR 461
G+L + C SG C C+E+V G +C R
Sbjct: 689 GGALSSMCSGPSGVCQCREHVVGKVCQR 716
Score = 93.6 bits (231), Expect = 1e-18
Identities = 146/675 (21%), Positives = 250/675 (37%), Gaps = 98/675 (14%)
Query: 840 GDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARD-C 898
GD C+ C G+Y +C+PC+C+ + C +G C H TA + C
Sbjct: 1662 GDSCQGCSPGYYRDHKGLYTG-RCVPCNCNGHSN-----QCQDGSGICVNCQHNTAGEHC 1715
Query: 899 SRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTG--QCTCRPGVTGQACDRCQLGFFG 956
RC G++ CR+C C S C G +C+C+ G TG C+RC G+FG
Sbjct: 1716 ERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFG 1775
Query: 957 FSIK---GCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQ 1012
K C+ C C+ G + CH G C+ + + + C D
Sbjct: 1776 NPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDD------------- 1821
Query: 1013 CPSCYALVKEEAAKLKARLTLTEGWLQGSDCGSPWGPLDILLG-EAPRGDVYQGHHLLPG 1071
C SC + + A + +L L + LQG + G L+ + E D+ + L
Sbjct: 1822 CDSCVMTLLNDLATMGEQLRLVKSQLQGLSASA--GLLEQMRHMETQAKDL---RNQLLN 1876
Query: 1072 AREAFLEQMMSLEGAVKAAREQLQRLNKGARCAQAGSQKTCTQLADLEAVLESSEEEILH 1131
R A +EG + + Q AQ S+K T ++ +S++E +
Sbjct: 1877 YRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVK 1936
Query: 1132 AAAILASLEIPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRALLASNTSYALL 1191
++ ++ H+ R ++H+ +A + +L
Sbjct: 1937 IKNVIRNV--------------HMLNRIRTWQKTHQGENNGLANSIRDSL---------- 1972
Query: 1192 WNLLEGRVALETQRDLEDRYQEVQAAQK---ALRTAVAEVLPEAESVLATVQQVGADTAP 1248
N E +++ DL R QE A K L L + + + + +D
Sbjct: 1973 -NEYEAKLS-----DLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTK 2026
Query: 1249 YLALLASPGALPQKSRAEDLGLKAKALEKTVASWQHMATEAARTLQTAAQATLRQTEPLT 1308
YL + +L Q + A L +EK+ ++ +A +L A Q E
Sbjct: 2027 YLT--TADSSLLQTNIALQL------MEKSQKEYEKLAA----SLNEARQ------ELSD 2068
Query: 1309 KLHQEARAALTQASSSVQAATVTVMGARTLLADLEGMKLQFPRPKDQAALQRKADSVSDR 1368
K+ + +R+A +S V+ A + L LE +K + A + +
Sbjct: 2069 KVRELSRSA--GKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENI 2126
Query: 1369 LLADTRKKTKQAERMLGNAAPLSSSA------KKKGREAEVLAKDSAKLAKALLRERKQA 1422
L A K AE AA S SA + R+A+ L+ +S KL +K+
Sbjct: 2127 LNA-----IKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKL 2181
Query: 1423 HRRASRLTSQTQATLQQASQQVLASEARRQELEEAERVGAGLSEMEQQIRESRISLEKDI 1482
+ S + Q TL + Q + L + G +++ I ++ + K
Sbjct: 2182 KQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLH-GIQRGDIDAMISSAKSMVRKAN 2240
Query: 1483 ETLSELLARLGSLDT 1497
+ E+L L + T
Sbjct: 2241 DITDEVLDGLNPIQT 2255
Score = 89.7 bits (221), Expect = 2e-17
Identities = 139/633 (21%), Positives = 247/633 (39%), Gaps = 118/633 (18%)
Query: 887 CSCLPHVTARDCSRCYPGFF----DLQPGRGCRSCKCHPLGSQEDQCHPKTGQC-TCRPG 941
C+C P C C PG++ L GR C C C+ +QC +G C C+
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGR-CVPCNCN---GHSNQCQDGSGICVNCQHN 1709
Query: 942 VTGQACDRCQLGFFGFSIKG-CRACRCSPLGAASAQCHENG---TCVCRPGFEGYKCDRC 997
G+ C+RCQ G++G ++ G CRAC C + + C NG C C+ G+ G +C+RC
Sbjct: 1710 TAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 1769
Query: 998 HDNFFLTAD--GTHCQQCP--------SCYALVKEEAAKLKARLTLTEGWLQGSDCGSPW 1047
+F G CQ C SC+ L + + + E + DC S
Sbjct: 1770 APGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAE---ECDDCDSCV 1826
Query: 1048 GPL--DI-LLGEAPRGDVYQGHHLLPGAREAFLEQMMSLEGAVKAAREQLQRLNKGARCA 1104
L D+ +GE R Q L A LEQM +E K R QL LN + +
Sbjct: 1827 MTLLNDLATMGEQLRLVKSQLQGL--SASAGLLEQMRHMETQAKDLRNQL--LNYRSAIS 1882
Query: 1105 QAGSQKTCTQLADLEAVLESSEEEILHAAAILASLEIPQEGPSQPTKWSHLATEARALAR 1164
GS+ +E E E+ +L+ ++ K L +
Sbjct: 1883 NHGSK------------IEGLERELTDLNQEFETLQ--EKAQVNSRKAQTLNNNVNRATQ 1928
Query: 1165 SHRDTATKIAATAWRALLASNTSYALLWNLLEGRVALETQRDLEDRYQ-EVQAAQKALRT 1223
S ++ KI N++ L R + +Q E ++R
Sbjct: 1929 SAKELDVKIK------------------NVIRNVHMLNRIRTWQKTHQGENNGLANSIRD 1970
Query: 1224 AVAEVLPEAESVLATVQQVGADTAPYLALLASPGALPQKSRAEDLGLKAKALEKTVASWQ 1283
++ E + + A +Q+ A + G + RA LG A+++ V
Sbjct: 1971 SLNEYEAKLSDLRARLQEAAAQAK------QANGLNQENERA--LG----AIQRQVKEIN 2018
Query: 1284 HMATEAARTLQTAAQATLRQTEPLTKLHQEARAALTQASSSVQAATVTVMGARTLLADLE 1343
+ ++ + L T A ++L QT +L ++++ + ++S+ A +L
Sbjct: 2019 SLQSDFTKYL-TTADSSLLQTNIALQLMEKSQKEYEKLAASLNEAR----------QELS 2067
Query: 1344 GMKLQFPRPKDQAALQRKADSVSDRLLADTRKKTKQAERMLGNAAPLSSSAKKKGREAEV 1403
+ R + +L +A+ + L ++ KQ E + NA+ G E
Sbjct: 2068 DKVRELSRSAGKTSLVEEAEKHARSL----QELAKQLEEIKRNAS---------GDELVR 2114
Query: 1404 LAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQ--------------QASQQVLASEA 1449
A D+A + +L K A A+R S +++ LQ ++ L +EA
Sbjct: 2115 CAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEA 2174
Query: 1450 RRQELEEAERVGAGLSEMEQQIRESRISLEKDI 1482
+ + + + V L+ ++Q + + ++++K++
Sbjct: 2175 KMTQKKLKQEVSPALNNLQQTL--NIVTVQKEV 2205
Score = 82.4 bits (202), Expect = 3e-15
Identities = 55/189 (29%), Positives = 74/189 (39%), Gaps = 15/189 (7%)
Query: 665 PPASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVC 724
P +S C C G TGQ C+ C G P+ C+ GT + N G C C
Sbjct: 547 PCSSVTGQCECRPGVTGQRCDRCLSG-----AYDFPHCQGSSSACDPAGTINSNLGYCQC 601
Query: 725 SHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESRE-VVCTHCPPGQRG 783
H EGP+C RC Y N C C C + E R+ HC G
Sbjct: 602 KLHVEGPTCSRC-KLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGG 660
Query: 784 RRCEVCDDGFFG-DPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDH 842
C+ C+DG+F + FG C CQC ++ C SG C +C + G
Sbjct: 661 DSCDTCEDGYFALEKSNYFG----CQGCQC--DIGGALSSMCSGPSGVC-QCREHVVGKV 713
Query: 843 CEHCQEGFY 851
C+ + +Y
Sbjct: 714 CQRPENNYY 722
Score = 54.3 bits (129), Expect = 9e-07
Identities = 22/58 (37%), Positives = 27/58 (46%), Gaps = 1/58 (1%)
Query: 426 GCRPCTCNPAGSLDT-CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
G PC C+P G+ C P G+CPC+ NV G C RC G + P C C
Sbjct: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLC 1319
Score = 43.9 bits (102), Expect = 0.001
Identities = 26/85 (30%), Positives = 32/85 (37%), Gaps = 5/85 (5%)
Query: 940 PGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCH-ENGTCVCRPGFEGYKCDRCH 998
P + C F KG C C P GA C E G C C+P G +C RC
Sbjct: 1241 PQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCA 1300
Query: 999 DNFFLTADGTHCQQCPSCYALVKEE 1023
+ C+ C SC + EE
Sbjct: 1301 TGHY---GFPRCKPC-SCGRRLCEE 1321
Score = 43.5 bits (101), Expect = 0.002
Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 19/95 (20%)
Query: 405 PTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSG----RCPCKENVEGNLCD 460
PTVT R +S GG C CN G + C+ + RC C+ + G CD
Sbjct: 280 PTVTR----RYYYSIKDISIGG--QCVCN--GHAEVCNINNPEKLFRCECQHHTCGETCD 331
Query: 461 RCRPGTFNLQPHNPAG------CSSCFCYGHSKVC 489
RC G +N + PA C +C C+GH+ C
Sbjct: 332 RCCTG-YNQRRWRPAAWEQSHECEACNCHGHASNC 365
Score = 38.5 bits (88), Expect = 0.052
Identities = 31/110 (28%), Positives = 43/110 (39%), Gaps = 20/110 (18%)
Query: 271 CKCN--GHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCN 328
CKC+ G S G G C C+ + G C+ C +D +A + C C
Sbjct: 631 CKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTC----EDGYFALEKSNY-FGCQGCQ 685
Query: 329 CS---GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWD 375
C S C+ G G C CR+H G C+R + N+Y D
Sbjct: 686 CDIGGALSSMCS---------GPSGVCQ-CREHVVGKVCQRPENNYYFPD 725
Score = 31.2 bits (69), Expect = 8.3
Identities = 47/220 (21%), Positives = 81/220 (36%), Gaps = 22/220 (10%)
Query: 1352 PKDQAALQR--KADSVSDRLLADTRKKTKQAERMLGNAAPLSSSAK--KKGREAEVLAKD 1407
PKD + + DS LL D +Q + LS+SA ++ R E AKD
Sbjct: 1810 PKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKD 1869
Query: 1408 SAKLAKALLRERKQAHRRASRLTSQTQATLQQASQQVLASEARRQELEEAERVGAGLSEM 1467
L LL R S++ + + E + +A+ + ++
Sbjct: 1870 ---LRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRA 1926
Query: 1468 EQQIRESRISLEKDIETLSELLARLGSLDTHQAP--------AQALNETQWALERLRLQL 1519
Q +E + ++ I + L THQ +LNE + L LR +L
Sbjct: 1927 TQSAKELDVKIKNVIRNVHMLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARL 1986
Query: 1520 GSPGSLQRKLSLLEQES-------QQQELQIQGFESDLAE 1552
+ ++ + L QE+ Q+Q +I +SD +
Sbjct: 1987 QEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTK 2026
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 282 bits (721), Expect = 2e-75
Identities = 210/635 (33%), Positives = 280/635 (44%), Gaps = 94/635 (14%)
Query: 290 CRCQHNTTGTDCERCLPFFQDRPWAR--GTAEAAHECLPCNCSGRSEECTFDRELFRSTG 347
CRC +G CE C F P GT C CNC+G + C
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGT------CSGCNCNGHASSCD---------P 775
Query: 348 HGGRCHHCRDHTAGPHCERCQENFYHWDPRMP---CQPCDC-------QSAGSLHLQCDD 397
G C +C+ +T GP C +C+ F+ + C+PC C + + + L D
Sbjct: 776 VYGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDG 835
Query: 398 TGTC-ACKPTVTGWKCDRCLPGFHS--LSEGG-CRPCT-----CNPAGSLDTCDPRSGR- 447
TC AC P TG +C+ C PG+ + GG CRP C+ GS+ T SG
Sbjct: 836 QATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGT----SGEA 891
Query: 448 CPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVCASTAQFQVHHILSDFHQG 507
C CK NV G LC+ C G+F+L NP GC CFC G S+ C S++ + + H
Sbjct: 892 CRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFCMGVSRHCTSSSWSR-----AQLHGA 946
Query: 508 AE--GWWARSVGGSEHPPQ---WSPNGVLLSPEDEEEL-------TAPEKFLGDQRFSYG 555
+E G ++ + S H +SP L L + P +FLGD+ SYG
Sbjct: 947 SEEPGHFSLTNAASTHTTNEGIFSPTPGELGFSSFHRLLSGPYFWSLPSRFLGDKVTSYG 1006
Query: 556 QPL--ILTFRVPPGDSPLPVQLRLEGTGLALSLRHSSLSGPQDAGHPREVELRFHLQETS 613
L +T R PG +PL Q + G + L H P G P + F Q
Sbjct: 1007 GELRFTVTQRSQPGSTPLHGQPLVVLQGNNIILEHHVAQEP-SPGQPSTFIVPFREQAWQ 1065
Query: 614 EDVAPPLPPFHFQRLLANLTSLRLRVSPGPSPAGPVFLTEVRLTSARPGLS--PPASWVE 671
P H LA + +L +R S PA ++ + + A P + PA VE
Sbjct: 1066 RPDGQPATREHLLMALAGIDTLLIRASYAQQPA-ESRVSGISMDVAVPEETGQDPALEVE 1124
Query: 672 ICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHG-TCDPNTGICV-CSHHTE 729
CSCP GY G C+ C GY R P G +C C+C+ H C+P TG C C HHTE
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTR-TPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTE 1183
Query: 730 GPSCERCLPGFYGNPFAGQADDCQPCPC-----PGQSACTT-IPESREVVCTHCPPGQRG 783
GP CE+C PG+YG+ G DCQ CPC GQ+A T + C C PG G
Sbjct: 1184 GPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSG 1243
Query: 784 RRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVG-NCDP---LSGHC-----LRC 834
R CE C G++G+P QPC + + P +G NCDP +S C +C
Sbjct: 1244 RHCERCAPGYYGNP----SQGQPCQR----DSQVPGPIGCNCDPQGSVSSQCDAAGQCQC 1295
Query: 835 LHNTTGDHCEHCQ-EGFYGSALAPRPADKCMPCSC 868
G C HC+ F+ SA P D C+PC C
Sbjct: 1296 KAQVEGLTCSHCRPHHFHLSASNP---DGCLPCFC 1327
Score = 262 bits (669), Expect = 2e-69
Identities = 215/690 (31%), Positives = 290/690 (42%), Gaps = 92/690 (13%)
Query: 204 NVAFSTLEGRPSAY--NFEESPGLQEW-------VTSTELLISLDRLNTFGDDIFKDPKV 254
+VA G+PS + F E Q W T LL++L ++T +
Sbjct: 1042 HVAQEPSPGQPSTFIVPFRE----QAWQRPDGQPATREHLLMALAGIDTL--------LI 1089
Query: 255 LQSYYYAVSDFSVGGRCKCNGHASECGPDVAGQLA-CRCQHNTTGTDCERCLPFFQDRPW 313
SY ++ V G E G D A ++ C C G C+ C + P
Sbjct: 1090 RASYAQQPAESRVSGISMDVAVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTP- 1148
Query: 314 ARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYH 373
+ C C+C G SE C + G C C+ HT GP CE+CQ +Y
Sbjct: 1149 ---SGLYLGTCERCSCHGHSEACEPET---------GACQGCQHHTEGPRCEQCQPGYYG 1196
Query: 374 WDPR---MPCQPCDC-------QSAGSLHLQCDDTGTC-ACKPTVTGWKCDRCLPGFHSL 422
R CQ C C Q+A + L D TC AC P +G C+RC PG++
Sbjct: 1197 DAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGN 1256
Query: 423 SEGG--CRP---------CTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQP 471
G C+ C C+P GS+ + +G+C CK VEG C CRP F+L
Sbjct: 1257 PSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRPHHFHLSA 1316
Query: 472 HNPAGCSSCFCYGHSKVCASTAQFQVHHILSDFHQGAEGWWA------RSVGGSEHPPQW 525
NP GC CFC G ++ CAS+A + H I + F G +A S E +
Sbjct: 1317 SNPDGCLPCFCMGITQQCASSA-YTRHLISTHFAPGDFQGFALVNPQRNSRLTGEFTVEP 1375
Query: 526 SPNGVLLSPEDEEEL-------TAPEKFLGDQRFSYGQPL--ILTFRVPPGDSPL-PVQL 575
P G LS + +L PE + GD+ +YG L L++ P SPL +
Sbjct: 1376 VPEGAQLSFGNFAQLGHESFYWQLPETYQGDKVAAYGGKLRYTLSYTAGPQGSPLSDPDV 1435
Query: 576 RLEGTGLALSLRHSSLSGPQDAGHPREVELRFHLQETSEDVAPPLPPFHFQRLLANLTSL 635
++ G + L +L GP+ R E+ F + P H LA+L L
Sbjct: 1436 QITGNNIMLVASQPALQGPE----RRSYEIMFREEFWRRPDGQPATREHLLMALADLDEL 1491
Query: 636 RLRVSPGPSPAGPVFLTEVRLTSARPGLS--PPASWVEICSCPTGYTGQFCESCAPGYKR 693
+R + P ++ V L A+PG S P A VE C CP GY G C+ CAPGY R
Sbjct: 1492 LIRATFSSVPLA-ASISAVSLEVAQPGPSNRPRALEVEECRCPPGYIGLSCQDCAPGYTR 1550
Query: 694 EMPQGGPYASCVPCTCNQHG-TCDPNTGIC-VCSHHTEGPSCERCLPGFYGNPFAGQADD 751
G C C CN H C P TG C C H+ G CE C PG+YG+ AG +D
Sbjct: 1551 -TGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPED 1609
Query: 752 CQPCPCPGQSACTTIPESREVV------CTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQ 805
CQPC CP + + E + CT C PG G+ CE C G+ G+P G
Sbjct: 1610 CQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCL 1669
Query: 806 PCHQCQCSGNVDPNAVGNCDPLSG-HCLRC 834
P Q V+ + + P G H LRC
Sbjct: 1670 P-ETNQAPLVVEVHPARSIVPQGGSHSLRC 1698
Score = 164 bits (415), Expect = 6e-40
Identities = 134/443 (30%), Positives = 195/443 (44%), Gaps = 57/443 (12%)
Query: 462 CRPGTFNLQPHNPAGCSSCFCYGHSKVCASTAQFQVHHILSDFHQGAEGWWARSVGGSEH 521
C G F L+ + A C CFC+G + VC ST +F+ I F Q + + +V
Sbjct: 505 CPDGHFYLE--HSAACLPCFCFGITSVCQSTRRFR-DQIRLRFDQ-PDDFKGVNVTMPAQ 560
Query: 522 P--PQWSPNGVLLSPEDEE----ELTA-----------PEKFLGDQRFSYGQPLILTFRV 564
P P S + + P E +L+ PE+FLG++ SYG L R
Sbjct: 561 PGTPPLSSTQLQIDPSLHEFQLVDLSRRFLVHDSFWALPEQFLGNKVDSYGGSLRYNVRY 620
Query: 565 PPGDSPL-PVQ---LRLEGTGLALSLRHSSLSGPQDAGHPREVELRFHLQETSEDVAPPL 620
L PVQ + L G G L R + P G + +++F + + P+
Sbjct: 621 ELARGMLEPVQRPDVVLMGAGYRLLSRGHT---PTQPGALNQRQVQFSEEHWVHESGRPV 677
Query: 621 PPFHFQRLLANLTSLRLRVSPGPSPAGPVFLTEVRL--TSARPGLSPPASWVEICSCPTG 678
++L +L ++ ++ A V L+++ + T A VE C CP G
Sbjct: 678 QRAELLQVLQSLEAVLIQTVYNTKMAS-VGLSDIAMDTTVTHATSHGRAHSVEECRCPIG 736
Query: 679 YTGQFCESCAPGYKREMPQGGPY-ASCVPCTCNQH-GTCDPNTGICV-CSHHTEGPSCER 735
Y+G CESC + R GGPY +C C CN H +CDP G C+ C H+TEGP C +
Sbjct: 737 YSGLSCESCDAHFTR--VPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEGPQCNK 794
Query: 736 CLPGFYGNPFAGQADDCQPCPCPGQSACTTIPES------REVVCTHCPPGQRGRRCEVC 789
C GF+G+ A C+PCPCP A ++ + C C PG GRRCE C
Sbjct: 795 CKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESC 854
Query: 790 DDGFFGDPLGLFGHPQPCHQ----CQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEH 845
G+ G+P+ G +P +Q C G++ SG RC +N G C
Sbjct: 855 APGYEGNPIQPGGKCRPVNQEIVRCDERGSMG---------TSGEACRCKNNVVGRLCNE 905
Query: 846 CQEGFYGSALAPRPADKCMPCSC 868
C +G + L+ R D C+ C C
Sbjct: 906 CADGSF--HLSTRNPDGCLKCFC 926
Score = 92.8 bits (229), Expect = 2e-18
Identities = 63/226 (27%), Positives = 88/226 (38%), Gaps = 33/226 (14%)
Query: 818 PNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQ 877
P G L C G C+ C G Y + C CSCH
Sbjct: 1112 PEETGQDPALEVEQCSCPPGYRGPSCQDCDTG-YTRTPSGLYLGTCERCSCHGHSEA--- 1167
Query: 878 MPCDPVTGQCS-CLPHVTARDCSRCYPGFF-DLQPG--RGCRSCKCH---PLGSQEDQC- 929
C+P TG C C H C +C PG++ D Q G + C+ C C+ G C
Sbjct: 1168 --CEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCF 1225
Query: 930 -----HPKTGQCTCRPGVTGQACDRCQLGFFGFSIKG--CR---------ACRCSPLGAA 973
HP C+ PG +G+ C+RC G++G +G C+ C C P G+
Sbjct: 1226 LDTDGHPTCDACS--PGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSV 1283
Query: 974 SAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCYAL 1019
S+QC G C C+ EG C C + F ++ C C+ +
Sbjct: 1284 SSQCDAAGQCQCKAQVEGLTCSHCRPHHF-HLSASNPDGCLPCFCM 1328
Score = 92.4 bits (228), Expect = 3e-18
Identities = 59/175 (33%), Positives = 80/175 (45%), Gaps = 28/175 (16%)
Query: 767 PESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLF-GHPQPCHQCQCSGNVDPNAVGNCD 825
P + EV CPPG G C+ C G+ GL+ GH C C+C+G+ D C
Sbjct: 1522 PRALEVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGH---CELCECNGHSDL-----CH 1573
Query: 826 PLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSC---HPQGSVSEQMPCDP 882
P +G C +C HN G+ CE C G+YG A A P D C PC+C +P+ S
Sbjct: 1574 PETGACSQCQHNAAGEFCELCAPGYYGDATAGTPED-CQPCACPLTNPENMFSRTCESLG 1632
Query: 883 VTG-QC-SCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQ 935
G +C +C P T + C +C PG+ +G QC P+T Q
Sbjct: 1633 AGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQG-------------GQCLPETNQ 1674
Score = 77.4 bits (189), Expect = 1e-13
Identities = 60/201 (29%), Positives = 80/201 (39%), Gaps = 28/201 (13%)
Query: 833 RCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQC-SCLP 891
RC +G CE C F P C C+C+ S CDPV G C +C
Sbjct: 732 RCPIGYSGLSCESCDAHFTRVPGGPY-LGTCSGCNCNGHAS-----SCDPVYGHCLNCQH 785
Query: 892 HVTARDCSRCYPGFFD---LQPGRGCRSCKCHPLGSQE---DQCHPKT-GQCTC---RPG 941
+ C++C GFF CR C C + + D C T GQ TC PG
Sbjct: 786 NTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPG 845
Query: 942 VTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENGT-------CVCRPGFEGYKC 994
TG+ C+ C G+ G I+ CR P+ +C E G+ C C+ G C
Sbjct: 846 YTGRRCESCAPGYEGNPIQPGGKCR--PVNQEIVRCDERGSMGTSGEACRCKNNVVGRLC 903
Query: 995 DRCHDNFF--LTADGTHCQQC 1013
+ C D F T + C +C
Sbjct: 904 NECADGSFHLSTRNPDGCLKC 924
Score = 70.1 bits (170), Expect = 2e-11
Identities = 39/130 (30%), Positives = 57/130 (43%), Gaps = 23/130 (17%)
Query: 886 QCSCLPHVTARDCSRCYPGFFDLQPGRG-----CRSCKCHPLGSQEDQCHPKTGQCT-CR 939
+C C P C C PG+ + G G C C+C+ D CHP+TG C+ C+
Sbjct: 1529 ECRCPPGYIGLSCQDCAPGY--TRTGSGLYLGHCELCECN---GHSDLCHPETGACSQCQ 1583
Query: 940 PGVTGQACDRCQLGFFGFSIKG----CRACRC---SPLGAASAQCHENGT-----CVCRP 987
G+ C+ C G++G + G C+ C C +P S C G C P
Sbjct: 1584 HNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEP 1643
Query: 988 GFEGYKCDRC 997
G+ G C++C
Sbjct: 1644 GYTGQYCEQC 1653
Score = 57.8 bits (138), Expect = 8e-08
Identities = 38/128 (29%), Positives = 53/128 (41%), Gaps = 19/128 (14%)
Query: 886 QCSCLPHVTARDCSRCYPGFFDLQPGR---GCRSCKCHPLGSQEDQCHPKTGQC-TCRPG 941
+C C + C C F + G C C C+ S C P G C C+
Sbjct: 730 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASS---CDPVYGHCLNCQHN 786
Query: 942 VTGQACDRCQLGFFGFSIK----GCRACRCSPLGAA---SAQC----HENGTC-VCRPGF 989
G C++C+ GFFG ++K CR C C + A+ S C TC C PG+
Sbjct: 787 TEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGY 846
Query: 990 EGYKCDRC 997
G +C+ C
Sbjct: 847 TGRRCESC 854
Score = 57.0 bits (136), Expect = 1e-07
Identities = 51/177 (28%), Positives = 73/177 (41%), Gaps = 24/177 (13%)
Query: 833 RCLHNTTGDHCEHCQEGFY--GSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCL 890
RC G C+ C G+ GS L C C C+ + C P TG CS
Sbjct: 1531 RCPPGYIGLSCQDCAPGYTRTGSGLY---LGHCELCECNGHSDL-----CHPETGACSQC 1582
Query: 891 PHVTARD-CSRCYPGFF-DLQPG--RGCRSCKCHPLGSQEDQ----CHPKTG---QCT-C 938
H A + C C PG++ D G C+ C C PL + E+ C +CT C
Sbjct: 1583 QHNAAGEFCELCAPGYYGDATAGTPEDCQPCAC-PLTNPENMFSRTCESLGAGGYRCTAC 1641
Query: 939 RPGVTGQACDRCQLGFFGF-SIKGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKC 994
PG TGQ C++C G+ G S++G + + + H + V + G +C
Sbjct: 1642 EPGYTGQYCEQCGPGYVGNPSVQGGQCLPETNQAPLVVEVHPARSIVPQGGSHSLRC 1698
Score = 47.8 bits (112), Expect = 9e-05
Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 10/91 (10%)
Query: 935 QCTCRPGVTGQACDRCQLGFF----GFSIKGCRACRCSPLGAASAQCHENGTCV-CRPGF 989
+C C G +G +C+ C F G + C C C+ G AS+ G C+ C+
Sbjct: 730 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCN--GHASSCDPVYGHCLNCQHNT 787
Query: 990 EGYKCDRCHDNFF---LTADGTHCQQCPSCY 1017
EG +C++C FF + A T C+ CP Y
Sbjct: 788 EGPQCNKCKAGFFGDAMKATATSCRPCPCPY 818
Score = 43.1 bits (100), Expect = 0.002
Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 26/102 (25%)
Query: 914 CRSCKCHPLGSQEDQCHPKTGQ---CTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPL 970
C +C+ P QCH C C G TG C+ Q A C P
Sbjct: 3845 CPTCRDRPC-QNGGQCHDSESSSYVCVCPAGFTGSRCEHSQ------------ALHCHP- 3890
Query: 971 GAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQ 1012
C + TCV RP GY C RCH L G C++
Sbjct: 3891 ----EACGPDATCVNRPDGRGYTC-RCH----LGRSGLRCEE 3923
Score = 33.5 bits (75), Expect = 1.7
Identities = 23/82 (28%), Positives = 32/82 (39%), Gaps = 8/82 (9%)
Query: 380 CQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNP-AGSL 438
C+ CQ+ G H + C C TG +C+ HS + C P C P A +
Sbjct: 3848 CRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCE------HSQAL-HCHPEACGPDATCV 3900
Query: 439 DTCDPRSGRCPCKENVEGNLCD 460
+ D R C C G C+
Sbjct: 3901 NRPDGRGYTCRCHLGRSGLRCE 3922
Score = 31.6 bits (70), Expect = 6.3
Identities = 13/44 (29%), Positives = 17/44 (38%)
Query: 983 CVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCYALVKEEAAK 1026
C C PG+ G C C + T G + C C EA +
Sbjct: 1126 CSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACE 1169
Score = 31.2 bits (69), Expect = 8.3
Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 13/55 (23%)
Query: 30 GRPQRC--LPVFENAAFGRLAQASHTC-----GSPPEDFCPHVGAAGAGAHCQRC 77
G PQ C P + + A G QA+HTC G P D C +G HC+RC
Sbjct: 1201 GTPQDCQLCPCYGDPAAG---QAAHTCFLDTDGHPTCDAC---SPGHSGRHCERC 1249
Score = 31.2 bits (69), Expect = 8.3
Identities = 28/93 (30%), Positives = 32/93 (34%), Gaps = 18/93 (19%)
Query: 752 CQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQ 811
C+ PC C ES VC CP G G RCE L HP+ C
Sbjct: 3848 CRDRPCQNGGQCHD-SESSSYVCV-CPAGFTGSRCE--------HSQALHCHPEAC---- 3893
Query: 812 CSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCE 844
D V D G+ RC +G CE
Sbjct: 3894 ---GPDATCVNRPDG-RGYTCRCHLGRSGLRCE 3922
Score = 31.2 bits (69), Expect = 8.3
Identities = 24/85 (28%), Positives = 30/85 (35%), Gaps = 33/85 (38%)
Query: 919 CHPLGSQEDQCHPKTGQCTCRPGVTGQACDR----CQLG---FFGFSIKGCRACRCSPLG 971
C P G E QC CR G G C+ CQL G + +G R
Sbjct: 4119 CMPAGEYEFQC-------LCRDGFKGDLCEHEENPCQLREPCLHGGTCQGTR-------- 4163
Query: 972 AASAQCHENGTCVCRPGFEGYKCDR 996
C+C PGF G +C +
Sbjct: 4164 -----------CLCLPGFSGPRCQQ 4177
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 277 bits (708), Expect = 7e-74
Identities = 146/366 (39%), Positives = 186/366 (50%), Gaps = 43/366 (11%)
Query: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT-CDPNTGICV-CSHHTEG 730
C C +G+ C+ C GY + SC PC CN+ CDP TG C C T G
Sbjct: 836 CPCHGEVSGRRCDRCLAGYFG-------FPSCHPCPCNRFAELCDPETGSCFNCGGFTTG 888
Query: 731 PSCERCLPGFYGNPFAGQADDCQPCPCPGQSA--------CTTIPESREVVCTHCPPGQR 782
+CERC+ G+YGNP +GQ C+PC CP + C S +V+C +C G
Sbjct: 889 RNCERCIDGYYGNPSSGQP--CRPCLCPDDPSSNQYFAHSCYQNLWSSDVIC-NCLQGYT 945
Query: 783 GRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDH 842
G +C C GF+G+P + G PC C C+ N+D +C ++G CLRCLHNT G +
Sbjct: 946 GTQCGECSTGFYGNPR-ISG--APCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGAN 1002
Query: 843 CEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMP-------CDPVTGQCSCLPHVTA 895
C+ C+ G YGSAL C CSCH G + P CDPVTG C CLP+VT
Sbjct: 1003 CQLCKPGHYGSALN----QTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTG 1058
Query: 896 RDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFF 955
C RC G+++L PGRGC+SC C P SQ C TGQC C+ G G+ C CQ ++
Sbjct: 1059 LACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYY 1118
Query: 956 GFSIKGCRACRCSPLGAASAQCH-ENGTCVCRPGFEGYKCDRC---HDNFFLTADGTHCQ 1011
G C C C+ G C + G C CR G G +CDRC H F T C
Sbjct: 1119 GDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPT-----CL 1173
Query: 1012 QCPSCY 1017
QC C+
Sbjct: 1174 QCHLCF 1179
Score = 251 bits (640), Expect = 5e-66
Identities = 171/508 (33%), Positives = 235/508 (46%), Gaps = 68/508 (13%)
Query: 35 CLPVFENAAFGRLAQ--ASHTCG-SPPEDFCPHVGAAGAGAHCQRCDAA-------DPQR 84
C P + GR Q AS TCG S + +C G C CD+ P
Sbjct: 28 CHPTTGDLLVGRNTQLMASSTCGLSRAQKYCILSYLEGE-QKCFICDSRFPYDPYDQPNS 86
Query: 85 HHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKFHTSRPES 144
H + + F E WWQS + G+ + V+I L L + +++ L F T RP +
Sbjct: 87 HTIENVIVSFEPDREKKWWQSEN---GLDH---VSIRLDLEALFRFSHLILTFKTFRPAA 140
Query: 145 FAIYKRSRADGPWEPYQFYSASCQKTYGR-PEGQYLRPGEDERVAFCTSEFSDISPLSGG 203
+ + + W+ +++++ C ++ GQ G+ C S++SDI P +GG
Sbjct: 141 MLVERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGD----IVCDSKYSDIEPSTGG 196
Query: 204 NVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIF--KDPKVLQSYYYA 261
V L+ N SP +Q+ VT T L I+ +L+T GD + + L YYYA
Sbjct: 197 EVVLKVLDPSFEIEN-PYSPYIQDLVTLTNLRINFTKLHTLGDALLGRRQNDSLDKYYYA 255
Query: 262 VSDFSVGGRCKCNGHASECGPD-------------VAGQLACRCQHNTTGTDCERCLPFF 308
+ + V G C CNGHASEC P V GQ C CQHNT G +CERC FF
Sbjct: 256 LYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQ--CVCQHNTDGPNCERCKDFF 313
Query: 309 QDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTG--HGGRCHHCRDHTAGPHCER 366
QD PW + C C+C+ S C FD + ++G GG C C+ +T G HC+R
Sbjct: 314 QDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDR 373
Query: 367 CQENFYHWDP------RMPCQPCDCQS----AGSLHLQCDD------TGTCACKPTVTGW 410
C+ FY DP C PC+C +G + + D G C CK V G
Sbjct: 374 CRPLFYR-DPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGA 432
Query: 411 KCDRCLPGFHSLSEG---GCRPCTCNPAGSLD--TCDPRSGRCPCKENVEGNLCDRCRPG 465
KCD+C P + LS GC+PC CNP GSL TCD +G+C C V G C+ C G
Sbjct: 433 KCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVG 492
Query: 466 TFNLQPHNPAGCSSCFC---YGHSKVCA 490
+ L H GCS C C +S VC+
Sbjct: 493 YWGLGNH-LHGCSPCDCDIGGAYSNVCS 519
Score = 166 bits (420), Expect = 2e-40
Identities = 111/384 (28%), Positives = 147/384 (38%), Gaps = 97/384 (25%)
Query: 705 VPCTCNQHGT----CDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQ 760
V C C+ G+ C G C C G C+RC G Y G C PC C Q
Sbjct: 767 VACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHG----CHPCHCHPQ 822
Query: 761 SACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNA 820
+ T+ + C C GRRC+ C G+FG P CH C C+ +
Sbjct: 823 GSKDTVCDQVTGQCP-CHGEVSGRRCDRCLAGYFGFP--------SCHPCPCNRFAE--- 870
Query: 821 VGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQM-- 878
CDP +G C C TTG +CE C +G+YG+ P C PC C S ++
Sbjct: 871 --LCDPETGSCFNCGGFTTGRNCERCIDGYYGN---PSSGQPCRPCLCPDDPSSNQYFAH 925
Query: 879 ----------------------------------------PCDP---------------- 882
PC P
Sbjct: 926 SCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCS 985
Query: 883 -VTGQC-SCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCH---------PLGSQEDQCHP 931
VTG+C CL + +C C PG + + CR C CH P G C P
Sbjct: 986 RVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDP 1045
Query: 932 KTGQCTCRPGVTGQACDRCQLGFFGF-SIKGCRACRCSPLGAASAQCHE-NGTCVCRPGF 989
TG C C P VTG ACDRC G++ +GC++C C P + S+ C + G C C+ G+
Sbjct: 1046 VTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGY 1105
Query: 990 EGYKCDRCHDNFFLTADGTHCQQC 1013
G +C C +N++ G C C
Sbjct: 1106 GGKRCSECQENYYGDPPG-RCIPC 1128
Score = 160 bits (406), Expect = 7e-39
Identities = 99/284 (34%), Positives = 129/284 (45%), Gaps = 39/284 (13%)
Query: 707 CTCNQHGT-CDPNT--------------GICVCSHHTEGPSCERCLPGFYGNPFAGQAD- 750
C CN H + C P G CVC H+T+GP+CERC F P+ AD
Sbjct: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADL 324
Query: 751 ---DCQPCPCPGQSA-----CTTIPESREV---VCTHCPPGQRGRRCEVCDDGFFGDPLG 799
C+ C C S+ TT S + VC C G+ C+ C F+ DPL
Sbjct: 325 QDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLK 384
Query: 800 LFGHPQPCHQCQCS--GNVDPN-AVGNCDP----LSGHCLRCLHNTTGDHCEHCQEGFYG 852
P C C+C G + V + DP ++G CL C N G C+ C+ YG
Sbjct: 385 TISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCL-CKENVEGAKCDQCKPNHYG 443
Query: 853 SALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPG- 911
L+ C PC C+P GS+ + CD TGQC CL +VT C C G++ L
Sbjct: 444 --LSATDPLGCQPCDCNPLGSLPF-LTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHL 500
Query: 912 RGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFF 955
GC C C G+ + C PK GQC CRP VTG++C G+F
Sbjct: 501 HGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYF 544
Score = 134 bits (337), Expect = 7e-31
Identities = 81/251 (32%), Positives = 111/251 (44%), Gaps = 41/251 (16%)
Query: 672 ICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQH------GTCDPNTGICV-C 724
IC+C GYTG C C+ G+ G A C PC CN + +C TG C+ C
Sbjct: 937 ICNCLQGYTGTQCGECSTGFYGNPRISG--APCQPCACNNNIDVTDPESCSRVTGECLRC 994
Query: 725 SHHTEGPSCERCLPGFYGNPFAGQADDCQPCPC-----------PGQSACTTIPESREVV 773
H+T+G +C+ C PG YG+ C+ C C PG AC P +
Sbjct: 995 LHNTQGANCQLCKPGHYGSAL---NQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACP 1051
Query: 774 CTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLR 833
C P G C+ C DG++ G + C C C ++ +CD L+G C
Sbjct: 1052 CL---PNVTGLACDRCADGYWNLVPG-----RGCQSCDCDPRTSQSS--HCDQLTGQC-P 1100
Query: 834 CLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHV 893
C G C CQE +YG P +C+PC C+ G +++ CDP TG C C V
Sbjct: 1101 CKLGYGGKRCSECQENYYGD-----PPGRCIPCDCNRAG--TQKPICDPDTGMCRCREGV 1153
Query: 894 TARDCSRCYPG 904
+ + C RC G
Sbjct: 1154 SGQRCDRCARG 1164
Score = 130 bits (328), Expect = 8e-30
Identities = 99/313 (31%), Positives = 127/313 (40%), Gaps = 39/313 (12%)
Query: 771 EVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQP--CHQCQCSGN-----VDPNAVGN 823
+ VC H G CE C D F P Q C C C+ + D
Sbjct: 294 QCVCQH---NTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLA 350
Query: 824 CDPLSGH-CLRCLHNTTGDHCEHCQEGFYGSALAP-RPADKCMPCSCHPQGSVSEQM--- 878
LSG C C HNT G HC+ C+ FY L C+PC C P G++S +
Sbjct: 351 SGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVS 410
Query: 879 PCDP----VTGQCSCLPHVTARDCSRCYPGFFDLQPGR--GCRSCKCHPLGSQED-QCHP 931
DP V GQC C +V C +C P + L GC+ C C+PLGS C
Sbjct: 411 HSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDV 470
Query: 932 KTGQCTCRPGVTGQACDRCQLGFFGFS--IKGCRACRCSPLGAASAQCH-ENGTCVCRPG 988
TGQC C VTG C+ C +G++G + GC C C GA S C +NG C CRP
Sbjct: 471 DTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPH 530
Query: 989 FEGYKCDRCHDNFFLTADGTHCQQCPSCYALVKEEAAKLKARLTLTEGWLQGSDCGSPWG 1048
G C +F + Y EEA L+ L GS+
Sbjct: 531 VTGRSCSEPAPGYFFAP--------LNFYLYEAEEATTLQGLAPL------GSETFGQSP 576
Query: 1049 PLDILLGEAPRGD 1061
+ ++LGE G+
Sbjct: 577 AVHVVLGEPVPGN 589
Score = 122 bits (305), Expect = 4e-27
Identities = 64/155 (41%), Positives = 79/155 (50%), Gaps = 9/155 (5%)
Query: 861 DKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCH 920
D + C CHPQGSV C + GQC C P V R C RC G +DL GC C CH
Sbjct: 764 DGAVACKCHPQGSVGSS--CSRLGGQCQCKPLVVGRCCDRCSTGSYDL-GHHGCHPCHCH 820
Query: 921 PLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHEN 980
P GS++ C TGQC C V+G+ CDRC G+FGF C C C+ A E
Sbjct: 821 PQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGF--PSCHPCPCNRF--AELCDPET 876
Query: 981 GTCVCRPGF-EGYKCDRCHDNFF-LTADGTHCQQC 1013
G+C GF G C+RC D ++ + G C+ C
Sbjct: 877 GSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPC 911
Score = 114 bits (286), Expect = 6e-25
Identities = 67/210 (31%), Positives = 88/210 (41%), Gaps = 24/210 (11%)
Query: 285 AGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFR 344
+ + C C TGT C C F P G C PC C+ + T R
Sbjct: 933 SSDVICNCLQGYTGTQCGECSTGFYGNPRISGAP-----CQPCACNNNID-VTDPESCSR 986
Query: 345 STGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGSLHLQCDD------- 397
TG RC H +T G +C+ C+ Y C+ C C ++G ++C
Sbjct: 987 VTGECLRCLH---NTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLC 1043
Query: 398 ---TGTCACKPTVTGWKCDRCLPGFHSLSEG-GCRPCTCNPAGSLDT-CDPRSGRCPCKE 452
TG C C P VTG CDRC G+ +L G GC+ C C+P S + CD +G+CPCK
Sbjct: 1044 DPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKL 1103
Query: 453 NVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
G C C+ N P C C C
Sbjct: 1104 GYGGKRCSECQE---NYYGDPPGRCIPCDC 1130
Score = 114 bits (285), Expect = 7e-25
Identities = 66/201 (32%), Positives = 87/201 (43%), Gaps = 12/201 (5%)
Query: 271 CKCNGHASECGPDVAGQLA---CRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPC 327
C CN + P+ ++ RC HNT G +C+ C P + + C C
Sbjct: 970 CACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGH----YGSALNQTCRRC-SC 1024
Query: 328 NCSGRSE-ECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQ 386
+ SG S EC G C C + G C+RC + +++ P CQ CDC
Sbjct: 1025 HASGVSPMECPPGGGACLCDPVTGACP-CLPNVTGLACDRCADGYWNLVPGRGCQSCDCD 1083
Query: 387 SAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGS-LDTCDPR 444
S CD TG C CK G +C C ++ G C PC CN AG+ CDP
Sbjct: 1084 PRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPD 1143
Query: 445 SGRCPCKENVEGNLCDRCRPG 465
+G C C+E V G CDRC G
Sbjct: 1144 TGMCRCREGVSGQRCDRCARG 1164
Score = 112 bits (279), Expect = 4e-24
Identities = 73/235 (31%), Positives = 94/235 (40%), Gaps = 38/235 (16%)
Query: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC- 329
C CN A C P+ C TTG +CERC+ + P + C PC C
Sbjct: 863 CPCNRFAELCDPETGS--CFNCGGFTTGRNCERCIDGYYGNP------SSGQPCRPCLCP 914
Query: 330 SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRM---PCQPCDCQ 386
S F +++ +C G C C FY +PR+ PCQPC C
Sbjct: 915 DDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYG-NPRISGAPCQPCACN 973
Query: 387 SAGSLHLQCDDTGTCA--------CKPTVTGWKCDRCLPGFH-SLSEGGCRPCTCN---- 433
+ ++ D +C+ C G C C PG + S CR C+C+
Sbjct: 974 N----NIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGV 1029
Query: 434 ------PAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
P G CDP +G CPC NV G CDRC G +NL P GC SC C
Sbjct: 1030 SPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGR--GCQSCDC 1082
Score = 95.1 bits (235), Expect = 5e-19
Identities = 44/98 (44%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
Query: 383 CDCQSAGSLHLQCDDTG-TCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDT- 440
C C GS+ C G C CKP V G CDRC G + L GC PC C+P GS DT
Sbjct: 769 CKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTV 828
Query: 441 CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCS 478
CD +G+CPC V G CDRC G F +P C+
Sbjct: 829 CDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCN 866
Score = 92.8 bits (229), Expect = 2e-18
Identities = 69/233 (29%), Positives = 92/233 (39%), Gaps = 46/233 (19%)
Query: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
C G V GQ C C +G C+RCL + P C PC C+
Sbjct: 819 CHPQGSKDTVCDQVTGQ--CPCHGEVSGRRCDRCLAGYFGFP----------SCHPCPCN 866
Query: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFY-HWDPRMPCQPCDCQSAG 389
+E C D E G C +C T G +CERC + +Y + PC+PC C
Sbjct: 867 RFAELC--DPET-------GSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDP 917
Query: 390 SLH----------LQCDDTGTCACKPTVTGWKCDRCLPGFHS---LSEGGCRPCTCNPAG 436
S + L D C C TG +C C GF+ +S C+PC CN
Sbjct: 918 SSNQYFAHSCYQNLWSSDV-ICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACN--N 974
Query: 437 SLDTCDPRS-----GRC-PCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCY 483
++D DP S G C C N +G C C+PG + + C C C+
Sbjct: 975 NIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQT--CRRCSCH 1025
Score = 89.0 bits (219), Expect = 3e-17
Identities = 40/103 (38%), Positives = 48/103 (46%), Gaps = 4/103 (3%)
Query: 913 GCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGA 972
G +CKCHP GS C GQC C+P V G+ CDRC G + GC C C P G+
Sbjct: 765 GAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGS 824
Query: 973 ASAQCHE-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCP 1014
C + G C C G +CDRC +F C CP
Sbjct: 825 KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYF---GFPSCHPCP 864
Score = 81.3 bits (199), Expect = 7e-15
Identities = 58/197 (29%), Positives = 78/197 (39%), Gaps = 26/197 (13%)
Query: 675 CPTGYTGQFCESCAPGYKREMPQ--GGPYASCVPCTCNQHGT---------CDPN----T 719
C GQ C+ C P + R+ + PYA C+PC C+ GT DP
Sbjct: 362 CQHNTEGQHCDRCRPLFYRDPLKTISDPYA-CIPCECDPDGTISGGICVSHSDPALGSVA 420
Query: 720 GICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPP 779
G C+C + EG C++C P YG A CQPC C + + + C
Sbjct: 421 GQCLCKENVEGAKCDQCKPNHYGLS-ATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLS 479
Query: 780 GQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCS-GNVDPNAVGNCDPLSGHCLRCLHNT 838
G CE C G++ GL H C C C G N C P +G C C +
Sbjct: 480 YVTGAHCEECTVGYW----GLGNHLHGCSPCDCDIGGAYSNV---CSPKNGQC-ECRPHV 531
Query: 839 TGDHCEHCQEGFYGSAL 855
TG C G++ + L
Sbjct: 532 TGRSCSEPAPGYFFAPL 548
Score = 73.6 bits (179), Expect = 1e-12
Identities = 43/137 (31%), Positives = 54/137 (39%), Gaps = 16/137 (11%)
Query: 673 CSCPTGYTGQFCESCAP---GYKREMPQGGPYASCVPCTCNQHG-----TCDPNTGICVC 724
C C G C+ C P G P G C PC CN G TCD +TG C+C
Sbjct: 423 CLCKENVEGAKCDQCKPNHYGLSATDPLG-----CQPCDCNPLGSLPFLTCDVDTGQCLC 477
Query: 725 SHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGR 784
+ G CE C G++G C PC C A + + + C C P GR
Sbjct: 478 LSYVTGAHCEECTVGYWG--LGNHLHGCSPCDCDIGGAYSNVCSPKNGQC-ECRPHVTGR 534
Query: 785 RCEVCDDGFFGDPLGLF 801
C G+F PL +
Sbjct: 535 SCSEPAPGYFFAPLNFY 551
Score = 58.9 bits (141), Expect = 4e-08
Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 4/83 (4%)
Query: 402 ACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCD 460
A P V C+R + + G C C+P GS+ +C G+C CK V G CD
Sbjct: 741 AMGPQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCD 800
Query: 461 RCRPGTFNLQPHNPAGCSSCFCY 483
RC G+++L H GC C C+
Sbjct: 801 RCSTGSYDLGHH---GCHPCHCH 820
Score = 43.5 bits (101), Expect = 0.002
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 940 PGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDRCH 998
P V AC+R + G AC+C P G+ + C G C C+P G CDRC
Sbjct: 744 PQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCS 803
Query: 999 -DNFFLTADGTHCQQC 1013
++ L G H C
Sbjct: 804 TGSYDLGHHGCHPCHC 819
Score = 32.7 bits (73), Expect = 2.8
Identities = 13/36 (36%), Positives = 20/36 (55%), Gaps = 6/36 (16%)
Query: 672 ICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPC 707
+C C G +GQ C+ CA G+ +E P +C+ C
Sbjct: 1146 MCRCREGVSGQRCDRCARGHSQEFP------TCLQC 1175
Score = 31.6 bits (70), Expect = 6.3
Identities = 19/68 (27%), Positives = 24/68 (35%), Gaps = 4/68 (5%)
Query: 980 NGTCVCRPGFEGYKCDRCHDNF----FLTADGTHCQQCPSCYALVKEEAAKLKARLTLTE 1035
+G CVC+ +G C+RC D F + A C SC L
Sbjct: 292 HGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLAS 351
Query: 1036 GWLQGSDC 1043
G L G C
Sbjct: 352 GGLSGGVC 359
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 253 bits (647), Expect = 8e-67
Identities = 168/501 (33%), Positives = 231/501 (46%), Gaps = 53/501 (10%)
Query: 24 ACYDGAGRPQRCLPVFENAAFGR--LAQASHTCG-SPPEDFCPHVGAAGAGAHCQRCDAA 80
AC GA C P + GR +AS TCG + PE +C G C +CD+
Sbjct: 20 ACSRGA-----CYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYGEWQM--KCCKCDSR 72
Query: 81 DPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKFHTS 140
P +++ S WWQS + V++ L L + +++ V ++F
Sbjct: 73 QPHNYYSHRVENVASSSGPMRWWQSQNDV------NPVSLQLDLDRRFQLQEVMMEFQGP 126
Query: 141 RPESFAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPGEDERVAFCTSEFSDISPL 200
P I + S W YQ+ +A C T+ P + RP + V + + L
Sbjct: 127 MPAGMLIERSSDFGKTWRVYQYLAADCTSTF--PRVRQGRPQSWQDVRCQSLPQRPNARL 184
Query: 201 SGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIFKDPKVLQSYYY 260
+GG V + ++ S +S +QE T L ++ RL + P S YY
Sbjct: 185 NGGKVQLNLMD-LVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHPP----SAYY 239
Query: 261 AVSDFSVGGRCKCNGHASEC--------GPDVAGQL--ACRCQHNTTGTDCERCLPFFQD 310
AVS + G C C+GHA C GP A Q+ C CQHNT G +CERC PF+ +
Sbjct: 240 AVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNN 299
Query: 311 RPWARGTAEAAHECLPCNCSGRSEECTFDRELFRST--GHGGRCHHCRDHTAGPHCERCQ 368
RPW + AHEC C+C+G SE C FD +F ++ +GG C +CRDHT G +CERCQ
Sbjct: 300 RPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQ 359
Query: 369 ENFYHWDPRMP-------CQPCDCQSAGSL-HLQCDD-TGTCACKPTVTGWKCDRCLPGF 419
+++ R P C C+C G++ CD TG C CK V G +CD C PGF
Sbjct: 360 LHYFR--NRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGF 417
Query: 420 HSLSEG---GCRPCTCNPAGSLD--TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNP 474
L+ GC C CN GS CD SGRC C NV G CD+C P + L +
Sbjct: 418 TGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLA--SG 475
Query: 475 AGCSSCFCYGHSKVCASTAQF 495
GC C C H+ + QF
Sbjct: 476 QGCEPCACDPHNSLSPQCNQF 496
Score = 197 bits (502), Expect = 5e-50
Identities = 120/348 (34%), Positives = 156/348 (44%), Gaps = 53/348 (15%)
Query: 707 CTCNQHGT-CDPNTG-------------ICVCSHHTEGPSCERCLPGFYGN----PFAGQ 748
C C+ H C P G +CVC H+T GP+CERC P FY N P GQ
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEGQ 308
Query: 749 -ADDCQPCPCPGQS-ACTTIPESREV-------VCTHCPPGQRGRRCEVCDDGFFGDPLG 799
A +CQ C C G S C P VC +C G+ CE C +F +
Sbjct: 309 DAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRP 368
Query: 800 LFGHPQPCHQCQCSGNVDPNAV---GNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALA 856
+ C C+C DP+ CDP++G C+ C + G+ C+ C+ GF G A
Sbjct: 369 GASIQETCISCEC----DPDGAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYA 423
Query: 857 PRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRS 916
C C C+ GS MPCD +G+C CLP+V C +C P + L G+GC
Sbjct: 424 NPQG--CHRCDCNILGS-RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEP 480
Query: 917 CKCHPLGSQEDQCHPKTGQCTCRPGVTGQACD-----RCQLGFFGFSIKGCRACRCSPLG 971
C C P S QC+ TGQC CR G G C +C +G GCRAC C G
Sbjct: 481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRG 540
Query: 972 AASAQCHE-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCYA 1018
C + +G C+CRPG G +CD+C + C + P C A
Sbjct: 541 TEGPGCDKASGRCLCRPGLTGPRCDQCQRGY--------CNRYPVCVA 580
Score = 164 bits (416), Expect = 5e-40
Identities = 129/435 (29%), Positives = 177/435 (40%), Gaps = 92/435 (21%)
Query: 615 DVAPPLPPFHFQRL--LANLTSLRL---RVSPGPS-----PAGPVFLTEVRLTSA----- 659
D+ +P Q++ + +T+LR+ R++P P P+ ++++RL +
Sbjct: 195 DLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHPPSAYYAVSQLRLQGSCFCHG 254
Query: 660 -------RPGLSPPASWV----EICSCPTGYTGQFCESCAPGYKR---EMPQGGPYASCV 705
+PG S S ++C C G CE CAP Y +G C
Sbjct: 255 HADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQ 314
Query: 706 PCTCNQHG-TC--DPNT---------GIC-VCSHHTEGPSCERCLPGFYGN--PFAGQAD 750
C CN H TC DP G+C C HTEG +CERC ++ N P A +
Sbjct: 315 RCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQE 374
Query: 751 DCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQC 810
C C C A P C +G RC++C GF G + +PQ CH+C
Sbjct: 375 TCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTG---LTYANPQGCHRC 431
Query: 811 QCSGNVDPNAVGN-----CDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMP 865
C N +G+ CD SG CL CL N G C+ C + A C P
Sbjct: 432 DC------NILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAPYHWKLA----SGQGCEP 480
Query: 866 CSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCS----RCYPGFFDLQPGRGCRSCKCHP 921
C+C P S+S Q C+ TGQC C CS R P GCR+C C
Sbjct: 481 CACDPHNSLSPQ--CNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDF 538
Query: 922 LGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENG 981
G++ C +G+C CRPG+TG CD+CQ G+ C+
Sbjct: 539 RGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY----------------------CNRYP 576
Query: 982 TCV-CRPGFEGYKCD 995
CV C P F+ Y D
Sbjct: 577 VCVACHPCFQTYDAD 591
Score = 101 bits (251), Expect = 7e-21
Identities = 72/222 (32%), Positives = 92/222 (41%), Gaps = 35/222 (15%)
Query: 279 ECGPD----------VAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCN 328
EC PD V GQ C C+ + G C+ C P F +A + H C CN
Sbjct: 380 ECDPDGAVPGAPCDPVTGQ--CVCKEHVQGERCDLCKPGFTGLTYAN--PQGCHRC-DCN 434
Query: 329 CSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWD--PRMPCQPCDCQ 386
G + D E GRC C + GP C++C YHW C+PC C
Sbjct: 435 ILGSRRDMPCDEE-------SGRCL-CLPNVVGPKCDQCAP--YHWKLASGQGCEPCACD 484
Query: 387 SAGSLHLQCDD-TGTCACKPTVTGWKCD-----RCLPGFHSLSEGGCRPCTCNPAGSLDT 440
SL QC+ TG C C+ G C +C + GCR C C+ G+
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGP 544
Query: 441 -CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCF 481
CD SGRC C+ + G CD+C+ G N P A C CF
Sbjct: 545 GCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA-CHPCF 585
Score = 32.0 bits (71), Expect = 4.8
Identities = 73/361 (20%), Positives = 139/361 (38%), Gaps = 52/361 (14%)
Query: 1068 LLPGAREAFL------EQMMSLEGAVKAAREQLQRLNKGARCAQAGSQKTCTQLADLEAV 1121
+LP A AFL EQ+ ++ R+ ++ + A Q+ +Q+ TQ++ A
Sbjct: 821 VLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVS---AS 877
Query: 1122 LESSEEEILHAAAILASLEIPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRAL 1181
EE++ ++ + P +EA D+AT L
Sbjct: 878 RSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSAT--------VL 929
Query: 1182 LASNTSYALLWNLLEGRVAL-ETQRDLEDRYQEVQAAQKALRTAVAEVLPEAESVLATVQ 1240
N A+ L + L +T++D+ R + +QA + R+ V + E V+ ++
Sbjct: 930 QKMNEIQAIAARLPNVDLVLSQTKQDIA-RARRLQAEAEEARSRAHAVEGQVEDVVGNLR 988
Query: 1241 QVGADTAPYLALLASPGALPQKSRAEDLGLKAKALEKTVASWQHMATEAARTLQTAAQAT 1300
Q +AL + + SR+ + ++ VA Q + A + + T
Sbjct: 989 Q------GTVALQEAQDTMQGTSRS------LRLIQDRVAEVQQVLRPAEKLV---TSMT 1033
Query: 1301 LRQTEPLTKLHQEARAALTQASSSVQAATVTVMGARTLLADLEG---MKLQFPRPKD--- 1354
+ + T++ + A Q + +VQA + + L+ EG +K ++ KD
Sbjct: 1034 KQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRLG 1093
Query: 1355 -------QAALQRKADSVSDRLLADT-----RKKTKQAERMLGNAAPLSSSAKKKGREAE 1402
Q A + + ++ L +T R K + E + G+ A + SA G E
Sbjct: 1094 QSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKR 1153
Query: 1403 V 1403
V
Sbjct: 1154 V 1154
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 253 bits (647), Expect = 8e-67
Identities = 168/501 (33%), Positives = 231/501 (46%), Gaps = 53/501 (10%)
Query: 24 ACYDGAGRPQRCLPVFENAAFGR--LAQASHTCG-SPPEDFCPHVGAAGAGAHCQRCDAA 80
AC GA C P + GR +AS TCG + PE +C G C +CD+
Sbjct: 20 ACSRGA-----CYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYGEWQM--KCCKCDSR 72
Query: 81 DPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKFHTS 140
P +++ S WWQS + V++ L L + +++ V ++F
Sbjct: 73 QPHNYYSHRVENVASSSGPMRWWQSQNDV------NPVSLQLDLDRRFQLQEVMMEFQGP 126
Query: 141 RPESFAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPGEDERVAFCTSEFSDISPL 200
P I + S W YQ+ +A C T+ P + RP + V + + L
Sbjct: 127 MPAGMLIERSSDFGKTWRVYQYLAADCTSTF--PRVRQGRPQSWQDVRCQSLPQRPNARL 184
Query: 201 SGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIFKDPKVLQSYYY 260
+GG V + ++ S +S +QE T L ++ RL + P S YY
Sbjct: 185 NGGKVQLNLMD-LVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHPP----SAYY 239
Query: 261 AVSDFSVGGRCKCNGHASEC--------GPDVAGQL--ACRCQHNTTGTDCERCLPFFQD 310
AVS + G C C+GHA C GP A Q+ C CQHNT G +CERC PF+ +
Sbjct: 240 AVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNN 299
Query: 311 RPWARGTAEAAHECLPCNCSGRSEECTFDRELFRST--GHGGRCHHCRDHTAGPHCERCQ 368
RPW + AHEC C+C+G SE C FD +F ++ +GG C +CRDHT G +CERCQ
Sbjct: 300 RPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQ 359
Query: 369 ENFYHWDPRMP-------CQPCDCQSAGSL-HLQCDD-TGTCACKPTVTGWKCDRCLPGF 419
+++ R P C C+C G++ CD TG C CK V G +CD C PGF
Sbjct: 360 LHYFR--NRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGF 417
Query: 420 HSLSEG---GCRPCTCNPAGSLD--TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNP 474
L+ GC C CN GS CD SGRC C NV G CD+C P + L +
Sbjct: 418 TGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLA--SG 475
Query: 475 AGCSSCFCYGHSKVCASTAQF 495
GC C C H+ + QF
Sbjct: 476 QGCEPCACDPHNSLSPQCNQF 496
Score = 197 bits (502), Expect = 5e-50
Identities = 120/348 (34%), Positives = 156/348 (44%), Gaps = 53/348 (15%)
Query: 707 CTCNQHGT-CDPNTG-------------ICVCSHHTEGPSCERCLPGFYGN----PFAGQ 748
C C+ H C P G +CVC H+T GP+CERC P FY N P GQ
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEGQ 308
Query: 749 -ADDCQPCPCPGQS-ACTTIPESREV-------VCTHCPPGQRGRRCEVCDDGFFGDPLG 799
A +CQ C C G S C P VC +C G+ CE C +F +
Sbjct: 309 DAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRP 368
Query: 800 LFGHPQPCHQCQCSGNVDPNAV---GNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALA 856
+ C C+C DP+ CDP++G C+ C + G+ C+ C+ GF G A
Sbjct: 369 GASIQETCISCEC----DPDGAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYA 423
Query: 857 PRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRS 916
C C C+ GS MPCD +G+C CLP+V C +C P + L G+GC
Sbjct: 424 NPQG--CHRCDCNILGS-RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEP 480
Query: 917 CKCHPLGSQEDQCHPKTGQCTCRPGVTGQACD-----RCQLGFFGFSIKGCRACRCSPLG 971
C C P S QC+ TGQC CR G G C +C +G GCRAC C G
Sbjct: 481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRG 540
Query: 972 AASAQCHE-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCYA 1018
C + +G C+CRPG G +CD+C + C + P C A
Sbjct: 541 TEGPGCDKASGRCLCRPGLTGPRCDQCQRGY--------CNRYPVCVA 580
Score = 164 bits (416), Expect = 5e-40
Identities = 129/435 (29%), Positives = 177/435 (40%), Gaps = 92/435 (21%)
Query: 615 DVAPPLPPFHFQRL--LANLTSLRL---RVSPGPS-----PAGPVFLTEVRLTSA----- 659
D+ +P Q++ + +T+LR+ R++P P P+ ++++RL +
Sbjct: 195 DLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHPPSAYYAVSQLRLQGSCFCHG 254
Query: 660 -------RPGLSPPASWV----EICSCPTGYTGQFCESCAPGYKR---EMPQGGPYASCV 705
+PG S S ++C C G CE CAP Y +G C
Sbjct: 255 HADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQ 314
Query: 706 PCTCNQHG-TC--DPNT---------GIC-VCSHHTEGPSCERCLPGFYGN--PFAGQAD 750
C CN H TC DP G+C C HTEG +CERC ++ N P A +
Sbjct: 315 RCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQE 374
Query: 751 DCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQC 810
C C C A P C +G RC++C GF G + +PQ CH+C
Sbjct: 375 TCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTG---LTYANPQGCHRC 431
Query: 811 QCSGNVDPNAVGN-----CDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMP 865
C N +G+ CD SG CL CL N G C+ C + A C P
Sbjct: 432 DC------NILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAPYHWKLA----SGQGCEP 480
Query: 866 CSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCS----RCYPGFFDLQPGRGCRSCKCHP 921
C+C P S+S Q C+ TGQC C CS R P GCR+C C
Sbjct: 481 CACDPHNSLSPQ--CNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDF 538
Query: 922 LGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENG 981
G++ C +G+C CRPG+TG CD+CQ G+ C+
Sbjct: 539 RGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY----------------------CNRYP 576
Query: 982 TCV-CRPGFEGYKCD 995
CV C P F+ Y D
Sbjct: 577 VCVACHPCFQTYDAD 591
Score = 101 bits (251), Expect = 7e-21
Identities = 72/222 (32%), Positives = 92/222 (41%), Gaps = 35/222 (15%)
Query: 279 ECGPD----------VAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCN 328
EC PD V GQ C C+ + G C+ C P F +A + H C CN
Sbjct: 380 ECDPDGAVPGAPCDPVTGQ--CVCKEHVQGERCDLCKPGFTGLTYAN--PQGCHRC-DCN 434
Query: 329 CSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWD--PRMPCQPCDCQ 386
G + D E GRC C + GP C++C YHW C+PC C
Sbjct: 435 ILGSRRDMPCDEE-------SGRCL-CLPNVVGPKCDQCAP--YHWKLASGQGCEPCACD 484
Query: 387 SAGSLHLQCDD-TGTCACKPTVTGWKCD-----RCLPGFHSLSEGGCRPCTCNPAGSLDT 440
SL QC+ TG C C+ G C +C + GCR C C+ G+
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGP 544
Query: 441 -CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCF 481
CD SGRC C+ + G CD+C+ G N P A C CF
Sbjct: 545 GCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA-CHPCF 585
Score = 32.0 bits (71), Expect = 4.8
Identities = 73/361 (20%), Positives = 139/361 (38%), Gaps = 52/361 (14%)
Query: 1068 LLPGAREAFL------EQMMSLEGAVKAAREQLQRLNKGARCAQAGSQKTCTQLADLEAV 1121
+LP A AFL EQ+ ++ R+ ++ + A Q+ +Q+ TQ++ A
Sbjct: 821 VLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVS---AS 877
Query: 1122 LESSEEEILHAAAILASLEIPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRAL 1181
EE++ ++ + P +EA D+AT L
Sbjct: 878 RSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSAT--------VL 929
Query: 1182 LASNTSYALLWNLLEGRVAL-ETQRDLEDRYQEVQAAQKALRTAVAEVLPEAESVLATVQ 1240
N A+ L + L +T++D+ R + +QA + R+ V + E V+ ++
Sbjct: 930 QKMNEIQAIAARLPNVDLVLSQTKQDIA-RARRLQAEAEEARSRAHAVEGQVEDVVGNLR 988
Query: 1241 QVGADTAPYLALLASPGALPQKSRAEDLGLKAKALEKTVASWQHMATEAARTLQTAAQAT 1300
Q +AL + + SR+ + ++ VA Q + A + + T
Sbjct: 989 Q------GTVALQEAQDTMQGTSRS------LRLIQDRVAEVQQVLRPAEKLV---TSMT 1033
Query: 1301 LRQTEPLTKLHQEARAALTQASSSVQAATVTVMGARTLLADLEG---MKLQFPRPKD--- 1354
+ + T++ + A Q + +VQA + + L+ EG +K ++ KD
Sbjct: 1034 KQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRLG 1093
Query: 1355 -------QAALQRKADSVSDRLLADT-----RKKTKQAERMLGNAAPLSSSAKKKGREAE 1402
Q A + + ++ L +T R K + E + G+ A + SA G E
Sbjct: 1094 QSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKR 1153
Query: 1403 V 1403
V
Sbjct: 1154 V 1154
>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 253 bits (647), Expect = 8e-67
Identities = 168/501 (33%), Positives = 231/501 (46%), Gaps = 53/501 (10%)
Query: 24 ACYDGAGRPQRCLPVFENAAFGR--LAQASHTCG-SPPEDFCPHVGAAGAGAHCQRCDAA 80
AC GA C P + GR +AS TCG + PE +C G C +CD+
Sbjct: 20 ACSRGA-----CYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYGEWQM--KCCKCDSR 72
Query: 81 DPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKFHTS 140
P +++ S WWQS + V++ L L + +++ V ++F
Sbjct: 73 QPHNYYSHRVENVASSSGPMRWWQSQNDV------NPVSLQLDLDRRFQLQEVMMEFQGP 126
Query: 141 RPESFAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPGEDERVAFCTSEFSDISPL 200
P I + S W YQ+ +A C T+ P + RP + V + + L
Sbjct: 127 MPAGMLIERSSDFGKTWRVYQYLAADCTSTF--PRVRQGRPQSWQDVRCQSLPQRPNARL 184
Query: 201 SGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIFKDPKVLQSYYY 260
+GG V + ++ S +S +QE T L ++ RL + P S YY
Sbjct: 185 NGGKVQLNLMD-LVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHPP----SAYY 239
Query: 261 AVSDFSVGGRCKCNGHASEC--------GPDVAGQL--ACRCQHNTTGTDCERCLPFFQD 310
AVS + G C C+GHA C GP A Q+ C CQHNT G +CERC PF+ +
Sbjct: 240 AVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNN 299
Query: 311 RPWARGTAEAAHECLPCNCSGRSEECTFDRELFRST--GHGGRCHHCRDHTAGPHCERCQ 368
RPW + AHEC C+C+G SE C FD +F ++ +GG C +CRDHT G +CERCQ
Sbjct: 300 RPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQ 359
Query: 369 ENFYHWDPRMP-------CQPCDCQSAGSL-HLQCDD-TGTCACKPTVTGWKCDRCLPGF 419
+++ R P C C+C G++ CD TG C CK V G +CD C PGF
Sbjct: 360 LHYFR--NRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGF 417
Query: 420 HSLSEG---GCRPCTCNPAGSLD--TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNP 474
L+ GC C CN GS CD SGRC C NV G CD+C P + L +
Sbjct: 418 TGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLA--SG 475
Query: 475 AGCSSCFCYGHSKVCASTAQF 495
GC C C H+ + QF
Sbjct: 476 QGCEPCACDPHNSLSPQCNQF 496
Score = 197 bits (502), Expect = 5e-50
Identities = 120/348 (34%), Positives = 156/348 (44%), Gaps = 53/348 (15%)
Query: 707 CTCNQHGT-CDPNTG-------------ICVCSHHTEGPSCERCLPGFYGN----PFAGQ 748
C C+ H C P G +CVC H+T GP+CERC P FY N P GQ
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEGQ 308
Query: 749 -ADDCQPCPCPGQS-ACTTIPESREV-------VCTHCPPGQRGRRCEVCDDGFFGDPLG 799
A +CQ C C G S C P VC +C G+ CE C +F +
Sbjct: 309 DAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRP 368
Query: 800 LFGHPQPCHQCQCSGNVDPNAV---GNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALA 856
+ C C+C DP+ CDP++G C+ C + G+ C+ C+ GF G A
Sbjct: 369 GASIQETCISCEC----DPDGAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYA 423
Query: 857 PRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRS 916
C C C+ GS MPCD +G+C CLP+V C +C P + L G+GC
Sbjct: 424 NPQG--CHRCDCNILGS-RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEP 480
Query: 917 CKCHPLGSQEDQCHPKTGQCTCRPGVTGQACD-----RCQLGFFGFSIKGCRACRCSPLG 971
C C P S QC+ TGQC CR G G C +C +G GCRAC C G
Sbjct: 481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRG 540
Query: 972 AASAQCHE-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCYA 1018
C + +G C+CRPG G +CD+C + C + P C A
Sbjct: 541 TEGPGCDKASGRCLCRPGLTGPRCDQCQRGY--------CNRYPVCVA 580
Score = 164 bits (416), Expect = 5e-40
Identities = 129/435 (29%), Positives = 177/435 (40%), Gaps = 92/435 (21%)
Query: 615 DVAPPLPPFHFQRL--LANLTSLRL---RVSPGPS-----PAGPVFLTEVRLTSA----- 659
D+ +P Q++ + +T+LR+ R++P P P+ ++++RL +
Sbjct: 195 DLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHPPSAYYAVSQLRLQGSCFCHG 254
Query: 660 -------RPGLSPPASWV----EICSCPTGYTGQFCESCAPGYKR---EMPQGGPYASCV 705
+PG S S ++C C G CE CAP Y +G C
Sbjct: 255 HADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQ 314
Query: 706 PCTCNQHG-TC--DPNT---------GIC-VCSHHTEGPSCERCLPGFYGN--PFAGQAD 750
C CN H TC DP G+C C HTEG +CERC ++ N P A +
Sbjct: 315 RCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQE 374
Query: 751 DCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQC 810
C C C A P C +G RC++C GF G + +PQ CH+C
Sbjct: 375 TCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTG---LTYANPQGCHRC 431
Query: 811 QCSGNVDPNAVGN-----CDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMP 865
C N +G+ CD SG CL CL N G C+ C + A C P
Sbjct: 432 DC------NILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAPYHWKLA----SGQGCEP 480
Query: 866 CSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCS----RCYPGFFDLQPGRGCRSCKCHP 921
C+C P S+S Q C+ TGQC C CS R P GCR+C C
Sbjct: 481 CACDPHNSLSPQ--CNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDF 538
Query: 922 LGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENG 981
G++ C +G+C CRPG+TG CD+CQ G+ C+
Sbjct: 539 RGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY----------------------CNRYP 576
Query: 982 TCV-CRPGFEGYKCD 995
CV C P F+ Y D
Sbjct: 577 VCVACHPCFQTYDAD 591
Score = 101 bits (251), Expect = 7e-21
Identities = 72/222 (32%), Positives = 92/222 (41%), Gaps = 35/222 (15%)
Query: 279 ECGPD----------VAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCN 328
EC PD V GQ C C+ + G C+ C P F +A + H C CN
Sbjct: 380 ECDPDGAVPGAPCDPVTGQ--CVCKEHVQGERCDLCKPGFTGLTYAN--PQGCHRC-DCN 434
Query: 329 CSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWD--PRMPCQPCDCQ 386
G + D E GRC C + GP C++C YHW C+PC C
Sbjct: 435 ILGSRRDMPCDEE-------SGRCL-CLPNVVGPKCDQCAP--YHWKLASGQGCEPCACD 484
Query: 387 SAGSLHLQCDD-TGTCACKPTVTGWKCD-----RCLPGFHSLSEGGCRPCTCNPAGSLDT 440
SL QC+ TG C C+ G C +C + GCR C C+ G+
Sbjct: 485 PHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGP 544
Query: 441 -CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCF 481
CD SGRC C+ + G CD+C+ G N P A C CF
Sbjct: 545 GCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA-CHPCF 585
Score = 32.0 bits (71), Expect = 4.8
Identities = 73/361 (20%), Positives = 139/361 (38%), Gaps = 52/361 (14%)
Query: 1068 LLPGAREAFL------EQMMSLEGAVKAAREQLQRLNKGARCAQAGSQKTCTQLADLEAV 1121
+LP A AFL EQ+ ++ R+ ++ + A Q+ +Q+ TQ++ A
Sbjct: 821 VLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVS---AS 877
Query: 1122 LESSEEEILHAAAILASLEIPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRAL 1181
EE++ ++ + P +EA D+AT L
Sbjct: 878 RSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSAT--------VL 929
Query: 1182 LASNTSYALLWNLLEGRVAL-ETQRDLEDRYQEVQAAQKALRTAVAEVLPEAESVLATVQ 1240
N A+ L + L +T++D+ R + +QA + R+ V + E V+ ++
Sbjct: 930 QKMNEIQAIAARLPNVDLVLSQTKQDIA-RARRLQAEAEEARSRAHAVEGQVEDVVGNLR 988
Query: 1241 QVGADTAPYLALLASPGALPQKSRAEDLGLKAKALEKTVASWQHMATEAARTLQTAAQAT 1300
Q +AL + + SR+ + ++ VA Q + A + + T
Sbjct: 989 Q------GTVALQEAQDTMQGTSRS------LRLIQDRVAEVQQVLRPAEKLV---TSMT 1033
Query: 1301 LRQTEPLTKLHQEARAALTQASSSVQAATVTVMGARTLLADLEG---MKLQFPRPKD--- 1354
+ + T++ + A Q + +VQA + + L+ EG +K ++ KD
Sbjct: 1034 KQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRLG 1093
Query: 1355 -------QAALQRKADSVSDRLLADT-----RKKTKQAERMLGNAAPLSSSAKKKGREAE 1402
Q A + + ++ L +T R K + E + G+ A + SA G E
Sbjct: 1094 QSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKR 1153
Query: 1403 V 1403
V
Sbjct: 1154 V 1154
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 234 bits (598), Expect = 4e-61
Identities = 159/486 (32%), Positives = 232/486 (47%), Gaps = 67/486 (13%)
Query: 2 AAAALLLGLALLAPRAAG-AGMGACYDGAGRPQRCLPVFENAAFGRLAQASHTCG-SPPE 59
A LL G ++A +G AG+ + + A C P N A GR A TCG + E
Sbjct: 5 ARLLLLWGCTVVAAGLSGVAGVSSRCEKA-----CNPRMGNLALGRKLWADTTCGQNATE 59
Query: 60 DFC---PHVGAAGAGAHCQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPT 116
+C + C +C+AA P H S + D + TWWQS +
Sbjct: 60 LYCFYSENTDLTCRQPKCDKCNAAYPHLAHLPSAMADSSFRFPRTWWQSAEDVHREK--- 116
Query: 117 SVNITLRLGKAYEITYVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQKTYGRPEG 176
I L L + T++ + F + RP + + + W+PY++++ +C T+G E
Sbjct: 117 ---IQLDLEAEFYFTHLIVMFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGL-ED 172
Query: 177 QYLRPGEDERVAFCTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLI 236
++ G A CTS++S P +GG V F L N S +QE + T L +
Sbjct: 173 DVVKKG-----AICTSKYSSPFPCTGGEVIFKALSPPYDTEN-PYSAKVQEQLKITNLRV 226
Query: 237 SLDRLNTFG---DDIFKDPKVLQSYYYAVSDFSVGGRCKCNGHASECGPD---------- 283
L + + +D+ ++P+ +YA+ DF V G C CNGHA +C P
Sbjct: 227 QLLKRQSCPCQRNDLNEEPQHFT--HYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPG 284
Query: 284 ----VAGQLACRCQHNTTGTDCERCLPFFQDRPW--ARGTAEAAHECLPCNCSGRSEECT 337
V G+ C C+HNT G+ C+ C P + DRPW A G A +EC C C+G ++ C
Sbjct: 285 TFHMVHGK--CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCH 342
Query: 338 FDRELFRSTGH--GGRCHHCRDHTAGPHCERCQENFYHWDPRMP------CQPCDCQSAG 389
FD ++ ++G+ GG C C+ +T G +C+RC+ FY D R P C+PC C G
Sbjct: 343 FDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYR-DLRRPFSAPDACKPCSCHPVG 401
Query: 390 SLHLQ------CDDT-GTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCD 442
S L CD + G C CKP V G +CDRC+ G+ + GCRPC C AGS CD
Sbjct: 402 SAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC--AGS---CD 456
Query: 443 PRSGRC 448
P +G C
Sbjct: 457 PITGDC 462
Score = 106 bits (264), Expect = 2e-22
Identities = 64/195 (32%), Positives = 85/195 (43%), Gaps = 40/195 (20%)
Query: 810 CQCSGNVDP----------NAVGNCDPLSGHCLRCLHNTTGDHCEHCQ--------EGFY 851
C C+G+ D A G + G C+ C HNT G HC+HC E
Sbjct: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
Query: 852 GSALAPRPADKCMPCSCHPQGSVSE------QMPCDPVTGQCSCLPHVT-ARDCSRCYPG 904
G AP ++C C C+ + + G C H T + C RC PG
Sbjct: 321 GKTGAP---NECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPG 377
Query: 905 FF-DLQ----PGRGCRSCKCHPLGS------QEDQCHPKTGQCTCRPGVTGQACDRCQLG 953
F+ DL+ C+ C CHP+GS C P G C C+PGV G+ CDRC +G
Sbjct: 378 FYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVG 437
Query: 954 FFGFSIKGCRACRCS 968
++GF GCR C C+
Sbjct: 438 YWGFGDYGCRPCDCA 452
Score = 94.4 bits (233), Expect = 8e-19
Identities = 76/286 (26%), Positives = 104/286 (36%), Gaps = 61/286 (21%)
Query: 707 CTCNQH----------------GTCDPNTGICVCSHHTEGPSCERCLPGFYGNPF----- 745
C CN H GT G C+C H+T G C+ C P + P+
Sbjct: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADG 321
Query: 746 -AGQADDCQPCPCPGQS-ACTTIPESREV-------VCTHCPPGQRGRRCEVCDDGFFGD 796
G ++C+ C C G + C E VC C G+ C+ C GF+ D
Sbjct: 322 KTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRD 381
Query: 797 PLGLFGHPQPCHQCQC----SGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYG 852
F P C C C S + N+V CDP +G C C G C+ C G++G
Sbjct: 382 LRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC-PCKPGVAGRRCDRCMVGYWG 440
Query: 853 SALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGR 912
C PC C GS CDP+TG C +++ Y D +P
Sbjct: 441 FG-----DYGCRPCDC--AGS------CDPITGDC-----ISSHTDIDWYHEVPDFRPVH 482
Query: 913 GCRSCKCHPLGSQED----QCHPKTGQCTCRPGVTGQACDRCQLGF 954
K P ED +G+C C+ G A C + +
Sbjct: 483 N----KSEPAWEWEDAQGFSALLHSGKCECKEQTLGNAKAFCGMKY 524
Score = 92.8 bits (229), Expect = 2e-18
Identities = 67/188 (35%), Positives = 85/188 (45%), Gaps = 45/188 (23%)
Query: 673 CSCPTGYTGQFCESCAPGYKR---EMPQG--GPYASCVPCTCNQHG-TC--DPNT----- 719
C C G C+ CAP Y E G G C C CN H TC D N
Sbjct: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASG 352
Query: 720 ----GIC-VCSHHTEGPSCERCLPGFYGN---PFAGQADDCQPCPC-PGQSACTTIPESR 770
G+C C H+TEG C+RC PGFY + PF+ D C+PC C P SA +P +
Sbjct: 353 NRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSA-PDACKPCSCHPVGSA--VLPANS 409
Query: 771 EVVC------THCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNC 824
C C PG GRRC+ C G++G G +G C C C+ G+C
Sbjct: 410 VTFCDPSNGDCPCKPGVAGRRCDRCMVGYWG--FGDYG----CRPCDCA--------GSC 455
Query: 825 DPLSGHCL 832
DP++G C+
Sbjct: 456 DPITGDCI 463
Score = 73.9 bits (180), Expect = 1e-12
Identities = 57/197 (28%), Positives = 77/197 (39%), Gaps = 42/197 (21%)
Query: 852 GSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPG 911
GS AD+C+P H V V G+C C + C C P + D +P
Sbjct: 260 GSCFCNGHADQCIPV--HGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYND-RPW 316
Query: 912 RG----------CRSCKCHPLGSQEDQCH-----------PKTGQCT-CRPGVTGQACDR 949
CR+CKC+ D CH G C C+ GQ C R
Sbjct: 317 EAADGKTGAPNECRTCKCN---GHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQR 373
Query: 950 CQLGFFG-----FSIK-GCRACRCSPLGAASAQCHE-------NGTCVCRPGFEGYKCDR 996
C+ GF+ FS C+ C C P+G+A + NG C C+PG G +CDR
Sbjct: 374 CKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDR 433
Query: 997 CHDNFFLTADGTHCQQC 1013
C ++ D C+ C
Sbjct: 434 CMVGYWGFGD-YGCRPC 449
Score = 44.3 bits (103), Expect = 0.001
Identities = 22/54 (40%), Positives = 26/54 (48%), Gaps = 7/54 (12%)
Query: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVCSH 726
C C G G+ C+ C GY G C PC C G+CDP TG C+ SH
Sbjct: 420 CPCKPGVAGRRCDRCMVGY-----WGFGDYGCRPCDC--AGSCDPITGDCISSH 466
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 231 bits (590), Expect = 3e-60
Identities = 145/433 (33%), Positives = 210/433 (48%), Gaps = 47/433 (10%)
Query: 86 HNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKA-YEITYVRLKFHTSRPES 144
H S++ D D T W S Q V I++ L Y++ Y+ ++F + +P
Sbjct: 340 HPLSFVND---NDVGTSWVSNVFTNITQLNQGVTISVDLENGQYQVFYIIIQFFSPQPTE 396
Query: 145 FAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPGEDERVAFCTSEFSDISPLSGGN 204
I ++ WE +Q+++ +C + G +P + + S+ +P S GN
Sbjct: 397 IRIQRKKENSLDWEDWQYFARNCGAFGMKNNGDLEKPDSVNCL-----QLSNFTPYSRGN 451
Query: 205 VAFSTLEG----RPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIFKDPKV-LQSYY 259
V FS L RP NF +P LQE+V +T++ R + G + V L+ Y
Sbjct: 452 VTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQI-----RFHFHGQYYTTETAVNLRHRY 506
Query: 260 YAVSDFSVGGRCKCNGHASECGPDVAGQ-LACRCQHN--TTGTDCERCLPFFQDRPWARG 316
YAV + ++ GRC+C+GHA C D Q C C T G C+RCLP + D+P+ +G
Sbjct: 507 YAVDEITISGRCQCHGHADNC--DTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQG 564
Query: 317 TAEAAHECLPCNCSGRSEEC-------TFDRELFRSTGHGGRCHHCRDHTAGPHCERCQE 369
A C PC C+ S+ C F E FR G GG C C +T G +CE C++
Sbjct: 565 DQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFR--GGGGVCDDCEHNTTGRNCELCKD 622
Query: 370 NFYHW---DPRM--PCQPCDCQSAGSLH--LQCDDT-GTCACKPTVTGWKCDRCLPGFHS 421
F+ DP C+PCDC + G+ + + CD G C CK V+G +C++C GF++
Sbjct: 623 YFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYN 682
Query: 422 LSE---GGCRPCTCNPAGSLD---TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPA 475
L E GC PC CN +G++D TC SG+C CK NV G CD C G L+ N
Sbjct: 683 LQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDV 742
Query: 476 GCSSCFCYGHSKV 488
GC C C H V
Sbjct: 743 GCEPCQCNLHGSV 755
Score = 186 bits (471), Expect = 2e-46
Identities = 110/337 (32%), Positives = 150/337 (44%), Gaps = 37/337 (10%)
Query: 707 CTCNQHG-TCDPNTGI--CVCSHH--TEGPSCERCLPGFYGNPFAG----QADDCQPCPC 757
C C+ H CD + C+CS TEG C+RCLP + PF A +C+PC C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577
Query: 758 PGQSACTTIPESREV-----------VCTHCPPGQRGRRCEVCDDGFF----GDPLGLFG 802
S S + VC C GR CE+C D FF DP +
Sbjct: 578 NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAI-- 635
Query: 803 HPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADK 862
C C C N CD + G C C + +G C CQ GFY L D
Sbjct: 636 --DVCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYN--LQELDPDG 690
Query: 863 CMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGR--GCRSCKCH 920
C PC+C+ G+V + C +GQC C +V C C GF L+ GC C+C+
Sbjct: 691 CSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCN 750
Query: 921 PLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGA-ASAQCH- 978
GS C+P +GQC C+ G CD C+ F+G + C+AC C G+ C+
Sbjct: 751 LHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNA 810
Query: 979 ENGTCVCRPGFEGYKCDRC-HDNFFLTADGTH-CQQC 1013
+ G C+C+P EG +C++C NF+L + + C C
Sbjct: 811 KTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPC 847
Score = 182 bits (463), Expect = 2e-45
Identities = 109/338 (32%), Positives = 156/338 (46%), Gaps = 30/338 (8%)
Query: 673 CSCPTGYTGQFCESCAPGYK--REMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSH 726
C C G C+ C G+K R G C PC CN HG+ C+P++G C C
Sbjct: 715 CKCKANVIGLRCDHCNFGFKFLRSFNDVG----CEPCQCNLHGSVNKFCNPHSGQCECKK 770
Query: 727 HTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACT-TIPESREVVCTHCPPGQRGRR 785
+G C+ C FYG +C+ C C + T+ ++ C C P GR+
Sbjct: 771 EAKGLQCDTCRENFYGL----DVTNCKACDCDTAGSLPGTVCNAKTGQCI-CKPNVEGRQ 825
Query: 786 CEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEH 845
C C +G F PC+ C +G ++ + + C+ +G C C TG C
Sbjct: 826 CNKCLEGNFYLRQNNSFLCLPCN-CDKTGTINGSLL--CNKSTGQC-PCKLGVTGLRCNQ 881
Query: 846 CQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGF 905
C+ Y L C C C G++ + CDP++GQC C+P+ R C++C PGF
Sbjct: 882 CEPHRYN--LTIDNFQHCQMCECDSLGTLPGTI-CDPISGQCLCVPNRQGRRCNQCQPGF 938
Query: 906 FDLQPGR--GCRSCKCHPLGSQEDQCHPKTGQCTCRPG-VTGQACDRCQLGFFGFSIKG- 961
+ + PG GC C CH G+ C+ TGQC C+ + GQ CD+C+ +FGF +
Sbjct: 939 Y-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTG 997
Query: 962 -CRACRCSPLGAASAQCH-ENGTCVCRPGFEGYKCDRC 997
C+ C C GA + CH G C C+ G KCD C
Sbjct: 998 RCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 176 bits (446), Expect = 2e-43
Identities = 117/392 (29%), Positives = 174/392 (44%), Gaps = 42/392 (10%)
Query: 673 CSCPTGYTGQFCESCAPGYK--REMPQGGPYASCVPCTCNQHGT------CDPNTGICVC 724
C+C +G+ C C G+ +E+ G C PC CN GT C N+G C C
Sbjct: 662 CNCKRHVSGRQCNQCQNGFYNLQELDPDG----CSPCNCNTSGTVDGDITCHQNSGQCKC 717
Query: 725 SHHTEGPSCERCLPGFYGNPFAGQADD--CQPCPCPGQSACTTIPESREVVCTHCPPGQR 782
+ G C+ C GF F +D C+PC C + C C +
Sbjct: 718 KANVIGLRCDHCNFGF---KFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEAK 773
Query: 783 GRRCEVCDDGFFGDPLGLFGHPQPCHQCQC--SGNVDPNAVGNCDPLSGHCLRCLHNTTG 840
G +C+ C + F+G + C C C +G++ P V C+ +G C+ C N G
Sbjct: 774 GLQCDTCRENFYGLDV------TNCKACDCDTAGSL-PGTV--CNAKTGQCI-CKPNVEG 823
Query: 841 DHCEHCQEG-FYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCS 899
C C EG FY L + C+PC+C G+++ + C+ TGQC C VT C+
Sbjct: 824 RQCNKCLEGNFY---LRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCN 880
Query: 900 RCYPGFFDLQPG--RGCRSCKCHPLGSQEDQ-CHPKTGQCTCRPGVTGQACDRCQLGFF- 955
+C P ++L + C+ C+C LG+ C P +GQC C P G+ C++CQ GF+
Sbjct: 881 QCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYI 940
Query: 956 -GFSIKGCRACRCSPLGAASAQCHE-NGTCVCRPG-FEGYKCDRCHDNFF-LTADGTHCQ 1011
+ GC C C GA + C+ G CVC+ G +CD+C D++F CQ
Sbjct: 941 SPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQ 1000
Query: 1012 QCPSCYALVKEEAAKLKARLTLTEGWLQGSDC 1043
C + E L + ++ GS C
Sbjct: 1001 PCNCHLSGALNETCHLVTGQCFCKQFVTGSKC 1032
Score = 173 bits (439), Expect = 1e-42
Identities = 116/372 (31%), Positives = 161/372 (43%), Gaps = 54/372 (14%)
Query: 675 CPTGYTGQFCESCAPGYKREMPQGGPYAS--CVPCTCNQHGT------CDPNTGICVCSH 726
C TG+ CE C + R++ P A C PC C+ GT CD G C C
Sbjct: 608 CEHNTTGRNCELCKDYFFRQVG-ADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKR 666
Query: 727 HTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTH------CPPG 780
H G C +C GFY N D C PC C T+ ++ C C
Sbjct: 667 HVSGRQCNQCQNGFY-NLQELDPDGCSPCNCN-----TSGTVDGDITCHQNSGQCKCKAN 720
Query: 781 QRGRRCEVCDDGF-----FGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCL 835
G RC+ C+ GF F D C CQC+ + N C+P SG C C
Sbjct: 721 VIGLRCDHCNFGFKFLRSFNDV--------GCEPCQCNLHGSVNKF--CNPHSGQC-ECK 769
Query: 836 HNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTA 895
G C+ C+E FYG + C C C GS+ + C+ TGQC C P+V
Sbjct: 770 KEAKGLQCDTCRENFYGLDVT-----NCKACDCDTAGSLPGTV-CNAKTGQCICKPNVEG 823
Query: 896 RDCSRCYPGFFDLQPGRG--CRSCKCHPLGSQEDQ--CHPKTGQCTCRPGVTGQACDRCQ 951
R C++C G F L+ C C C G+ C+ TGQC C+ GVTG C++C+
Sbjct: 824 RQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCE 883
Query: 952 LGFFGFSIKG---CRACRCSPLGAASAQCHE--NGTCVCRPGFEGYKCDRCHDNFFLT-A 1005
+ +I C+ C C LG + +G C+C P +G +C++C F+++
Sbjct: 884 PHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPG 943
Query: 1006 DGTHCQQCPSCY 1017
+ T C C SC+
Sbjct: 944 NATGCLPC-SCH 954
Score = 170 bits (430), Expect = 1e-41
Identities = 122/382 (31%), Positives = 168/382 (43%), Gaps = 58/382 (15%)
Query: 672 ICSCPTGYTGQFCESCAPGYKREMPQGGP--YA-SCVPCTCNQHG-------TCDP---- 717
+CS + G C+ C P Y + + G YA +C PC CN H + DP
Sbjct: 537 LCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE 596
Query: 718 ----NTGIC-VCSHHTEGPSCERCLPGFYGNPFAGQA--DDCQPCPCPGQSACTTIPESR 770
G+C C H+T G +CE C F+ A + D C+PC C T +
Sbjct: 597 HFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCD-----TVGTRNG 651
Query: 771 EVVC------THCPPGQRGRRCEVCDDGFFG----DPLGLFGHPQPCHQCQCSGNVDPNA 820
++C +C GR+C C +GF+ DP G PC+ C SG VD +
Sbjct: 652 SILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGC----SPCN-CNTSGTVDGDI 706
Query: 821 VGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPC 880
C SG C +C N G C+HC GF L C PC C+ GSV++ C
Sbjct: 707 --TCHQNSGQC-KCKANVIGLRCDHCNFGF--KFLRSFNDVGCEPCQCNLHGSVNKF--C 759
Query: 881 DPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQ-CHPKTGQCTCR 939
+P +GQC C C C F+ L C++C C GS C+ KTGQC C+
Sbjct: 760 NPHSGQCECKKEAKGLQCDTCRENFYGLDV-TNCKACDCDTAGSLPGTVCNAKTGQCICK 818
Query: 940 PGVTGQACDRCQLGFFGFSIKG---CRACRCSPLGA--ASAQCHEN-GTCVCRPGFEGYK 993
P V G+ C++C G F C C C G S C+++ G C C+ G G +
Sbjct: 819 PNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLR 878
Query: 994 CDRCHDN-FFLTADG-THCQQC 1013
C++C + + LT D HCQ C
Sbjct: 879 CNQCEPHRYNLTIDNFQHCQMC 900
Score = 165 bits (418), Expect = 3e-40
Identities = 101/309 (32%), Positives = 139/309 (44%), Gaps = 32/309 (10%)
Query: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT-----CDPNTGICVCSHH 727
C C G C++C RE G +C C C+ G+ C+ TG C+C +
Sbjct: 766 CECKKEAKGLQCDTC-----RENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPN 820
Query: 728 TEGPSCERCLPG-FY---GNPFAGQADDCQPCPCPGQSACT-TIPESREVVCTHCPPGQR 782
EG C +CL G FY N F C PC C ++ ++ C G
Sbjct: 821 VEGRQCNKCLEGNFYLRQNNSFL-----CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVT 875
Query: 783 GRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDH 842
G RC C+ + + F H Q C +C G + P + CDP+SG CL C+ N G
Sbjct: 876 GLRCNQCEPHRYNLTIDNFQHCQMC-ECDSLGTL-PGTI--CDPISGQCL-CVPNRQGRR 930
Query: 843 CEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLP-HVTARDCSRC 901
C CQ GFY ++P A C+PCSCH G+V+ C+ +TGQC C + + C +C
Sbjct: 931 CNQCQPGFY---ISPGNATGCLPCSCHTTGAVNHI--CNSLTGQCVCQDASIAGQRCDQC 985
Query: 902 YPGFFDLQPGRG-CRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIK 960
+F P G C+ C CH G+ + CH TGQC C+ VTG CD C +
Sbjct: 986 KDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVN 1045
Query: 961 GCRACRCSP 969
C +P
Sbjct: 1046 NLLGCSKTP 1054
Score = 125 bits (315), Expect = 2e-28
Identities = 79/285 (27%), Positives = 117/285 (41%), Gaps = 83/285 (29%)
Query: 271 CKCNGHASECGPDVA------------GQLACRCQHNTTGTDCERCLPFFQDRPWARGTA 318
C+CN H+ C +++ G + C+HNTTG +CE C +F + A
Sbjct: 575 CQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGA--DP 632
Query: 319 EAAHECLPCNCSG---RSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWD 375
A C PC+C R+ D+ GG+C+ C+ H +G C +CQ FY+
Sbjct: 633 SAIDVCKPCDCDTVGTRNGSILCDQI-------GGQCN-CKRHVSGRQCNQCQNGFYNLQ 684
Query: 376 PRMP--CQPCDCQSAGSLH--------------------LQCDD---------------- 397
P C PC+C ++G++ L+CD
Sbjct: 685 ELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGC 744
Query: 398 ------------------TGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD 439
+G C CK G +CD C F+ L C+ C C+ AGSL
Sbjct: 745 EPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLP 804
Query: 440 --TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
C+ ++G+C CK NVEG C++C G F L+ +N C C C
Sbjct: 805 GTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849
Score = 124 bits (311), Expect = 7e-28
Identities = 77/239 (32%), Positives = 111/239 (46%), Gaps = 25/239 (10%)
Query: 256 QSYYYAVSDFSVGG--RCKCNGHASECGPDVAGQLA--CRCQHNTTGTDCERCLPFFQDR 311
Q+ +Y + + G C CN + G Q + C+C+ N G C+ C F+
Sbjct: 677 QNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFK-- 734
Query: 312 PWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENF 371
+ R + C PC C+ F H G+C C+ G C+ C+ENF
Sbjct: 735 -FLRSFNDVG--CEPCQCNLHGSVNKF------CNPHSGQCE-CKKEAKGLQCDTCRENF 784
Query: 372 YHWDPRMPCQPCDCQSAGSLH-LQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGG--- 426
Y D C+ CDC +AGSL C+ TG C CKP V G +C++CL G L +
Sbjct: 785 YGLDVTN-CKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFL 843
Query: 427 CRPCTCNPAGSLD---TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
C PC C+ G+++ C+ +G+CPCK V G C++C P +NL N C C C
Sbjct: 844 CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902
Score = 109 bits (272), Expect = 2e-23
Identities = 73/228 (32%), Positives = 107/228 (46%), Gaps = 35/228 (15%)
Query: 271 CKCNGHASE---CGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPC 327
C+CN H S C P +GQ C C+ G C+ C F C C
Sbjct: 747 CQCNLHGSVNKFCNPH-SGQ--CECKKEAKGLQCDTCRENFYGLD--------VTNCKAC 795
Query: 328 NC--SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQE-NFY-HWDPRMPCQPC 383
+C +G + + G+C C+ + G C +C E NFY + C PC
Sbjct: 796 DCDTAGSLPGTVCNAKT-------GQCI-CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPC 847
Query: 384 DCQSAGSLH--LQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGG---CRPCTCNPAGS 437
+C G+++ L C+ TG C CK VTG +C++C P ++L+ C+ C C+ G+
Sbjct: 848 NCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGT 907
Query: 438 L--DTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCY 483
L CDP SG+C C N +G C++C+PG F + P N GC C C+
Sbjct: 908 LPGTICDPISGQCLCVPNRQGRRCNQCQPG-FYISPGNATGCLPCSCH 954
Score = 95.5 bits (236), Expect = 4e-19
Identities = 59/195 (30%), Positives = 89/195 (45%), Gaps = 17/195 (8%)
Query: 290 CRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHG 349
C C+ TG C +C P + T + C C C T +
Sbjct: 868 CPCKLGVTGLRCNQCEPHRYNL-----TIDNFQHCQMCECDSLG---TLPGTICDPIS-- 917
Query: 350 GRCHHCRDHTAGPHCERCQENFYHWDPRMP-CQPCDCQSAGSLHLQCDD-TGTCACKP-T 406
G+C C + G C +CQ FY C PC C + G+++ C+ TG C C+ +
Sbjct: 918 GQCL-CVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDAS 976
Query: 407 VTGWKCDRCLPGFHSLSE--GGCRPCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCDRCR 463
+ G +CD+C + G C+PC C+ +G+L +TC +G+C CK+ V G+ CD C
Sbjct: 977 IAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036
Query: 464 PGTFNLQPHNPAGCS 478
P +L +N GCS
Sbjct: 1037 PSASHLDVNNLLGCS 1051
Score = 87.0 bits (214), Expect = 1e-16
Identities = 59/184 (32%), Positives = 86/184 (46%), Gaps = 23/184 (12%)
Query: 258 YYYAVSDFSVGGRCKCNG----HASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPW 313
Y + +F C+C+ + C P ++GQ C C N G C +C P F P
Sbjct: 887 YNLTIDNFQHCQMCECDSLGTLPGTICDP-ISGQ--CLCVPNRQGRRCNQCQPGFYISP- 942
Query: 314 ARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHT-AGPHCERCQENFY 372
G A CLPC+C L G+C C+D + AG C++C+++++
Sbjct: 943 --GNATG---CLPCSCHTTGAVNHICNSLT------GQCV-CQDASIAGQRCDQCKDHYF 990
Query: 373 HWDPRMP-CQPCDCQSAGSLHLQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPC 430
+DP+ CQPC+C +G+L+ C TG C CK VTG KCD C+P L C
Sbjct: 991 GFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050
Query: 431 TCNP 434
+ P
Sbjct: 1051 SKTP 1054
Score = 39.7 bits (91), Expect = 0.023
Identities = 26/70 (37%), Positives = 30/70 (42%), Gaps = 13/70 (18%)
Query: 430 CTCNPAGSLDTCDPRSG--RCPCKEN--VEGNLCDRCRPGTFNLQPHNPA------GCSS 479
C C+ G D CD S RC C + EG CDRC P +N +P C
Sbjct: 518 CQCH--GHADNCDTTSQPYRCLCSQESFTEGLHCDRCLP-LYNDKPFRQGDQVYAFNCKP 574
Query: 480 CFCYGHSKVC 489
C C HSK C
Sbjct: 575 CQCNSHSKSC 584
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 231 bits (590), Expect = 3e-60
Identities = 145/433 (33%), Positives = 210/433 (48%), Gaps = 47/433 (10%)
Query: 86 HNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKA-YEITYVRLKFHTSRPES 144
H S++ D D T W S Q V I++ L Y++ Y+ ++F + +P
Sbjct: 340 HPLSFVND---NDVGTSWVSNVFTNITQLNQGVTISVDLENGQYQVFYIIIQFFSPQPTE 396
Query: 145 FAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPGEDERVAFCTSEFSDISPLSGGN 204
I ++ WE +Q+++ +C + G +P + + S+ +P S GN
Sbjct: 397 IRIQRKKENSLDWEDWQYFARNCGAFGMKNNGDLEKPDSVNCL-----QLSNFTPYSRGN 451
Query: 205 VAFSTLEG----RPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIFKDPKV-LQSYY 259
V FS L RP NF +P LQE+V +T++ R + G + V L+ Y
Sbjct: 452 VTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQI-----RFHFHGQYYTTETAVNLRHRY 506
Query: 260 YAVSDFSVGGRCKCNGHASECGPDVAGQ-LACRCQHN--TTGTDCERCLPFFQDRPWARG 316
YAV + ++ GRC+C+GHA C D Q C C T G C+RCLP + D+P+ +G
Sbjct: 507 YAVDEITISGRCQCHGHADNC--DTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQG 564
Query: 317 TAEAAHECLPCNCSGRSEEC-------TFDRELFRSTGHGGRCHHCRDHTAGPHCERCQE 369
A C PC C+ S+ C F E FR G GG C C +T G +CE C++
Sbjct: 565 DQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFR--GGGGVCDDCEHNTTGRNCELCKD 622
Query: 370 NFYHW---DPRM--PCQPCDCQSAGSLH--LQCDDT-GTCACKPTVTGWKCDRCLPGFHS 421
F+ DP C+PCDC + G+ + + CD G C CK V+G +C++C GF++
Sbjct: 623 YFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYN 682
Query: 422 LSE---GGCRPCTCNPAGSLD---TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPA 475
L E GC PC CN +G++D TC SG+C CK NV G CD C G L+ N
Sbjct: 683 LQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDV 742
Query: 476 GCSSCFCYGHSKV 488
GC C C H V
Sbjct: 743 GCEPCQCNLHGSV 755
Score = 186 bits (471), Expect = 2e-46
Identities = 110/337 (32%), Positives = 150/337 (44%), Gaps = 37/337 (10%)
Query: 707 CTCNQHG-TCDPNTGI--CVCSHH--TEGPSCERCLPGFYGNPFAG----QADDCQPCPC 757
C C+ H CD + C+CS TEG C+RCLP + PF A +C+PC C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577
Query: 758 PGQSACTTIPESREV-----------VCTHCPPGQRGRRCEVCDDGFF----GDPLGLFG 802
S S + VC C GR CE+C D FF DP +
Sbjct: 578 NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAI-- 635
Query: 803 HPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADK 862
C C C N CD + G C C + +G C CQ GFY L D
Sbjct: 636 --DVCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYN--LQELDPDG 690
Query: 863 CMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGR--GCRSCKCH 920
C PC+C+ G+V + C +GQC C +V C C GF L+ GC C+C+
Sbjct: 691 CSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCN 750
Query: 921 PLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGA-ASAQCH- 978
GS C+P +GQC C+ G CD C+ F+G + C+AC C G+ C+
Sbjct: 751 LHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNA 810
Query: 979 ENGTCVCRPGFEGYKCDRC-HDNFFLTADGTH-CQQC 1013
+ G C+C+P EG +C++C NF+L + + C C
Sbjct: 811 KTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPC 847
Score = 182 bits (463), Expect = 2e-45
Identities = 109/338 (32%), Positives = 156/338 (46%), Gaps = 30/338 (8%)
Query: 673 CSCPTGYTGQFCESCAPGYK--REMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSH 726
C C G C+ C G+K R G C PC CN HG+ C+P++G C C
Sbjct: 715 CKCKANVIGLRCDHCNFGFKFLRSFNDVG----CEPCQCNLHGSVNKFCNPHSGQCECKK 770
Query: 727 HTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACT-TIPESREVVCTHCPPGQRGRR 785
+G C+ C FYG +C+ C C + T+ ++ C C P GR+
Sbjct: 771 EAKGLQCDTCRENFYGL----DVTNCKACDCDTAGSLPGTVCNAKTGQCI-CKPNVEGRQ 825
Query: 786 CEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEH 845
C C +G F PC+ C +G ++ + + C+ +G C C TG C
Sbjct: 826 CNKCLEGNFYLRQNNSFLCLPCN-CDKTGTINGSLL--CNKSTGQC-PCKLGVTGLRCNQ 881
Query: 846 CQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGF 905
C+ Y L C C C G++ + CDP++GQC C+P+ R C++C PGF
Sbjct: 882 CEPHRYN--LTIDNFQHCQMCECDSLGTLPGTI-CDPISGQCLCVPNRQGRRCNQCQPGF 938
Query: 906 FDLQPGR--GCRSCKCHPLGSQEDQCHPKTGQCTCRPG-VTGQACDRCQLGFFGFSIKG- 961
+ + PG GC C CH G+ C+ TGQC C+ + GQ CD+C+ +FGF +
Sbjct: 939 Y-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTG 997
Query: 962 -CRACRCSPLGAASAQCH-ENGTCVCRPGFEGYKCDRC 997
C+ C C GA + CH G C C+ G KCD C
Sbjct: 998 RCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 176 bits (446), Expect = 2e-43
Identities = 117/392 (29%), Positives = 174/392 (44%), Gaps = 42/392 (10%)
Query: 673 CSCPTGYTGQFCESCAPGYK--REMPQGGPYASCVPCTCNQHGT------CDPNTGICVC 724
C+C +G+ C C G+ +E+ G C PC CN GT C N+G C C
Sbjct: 662 CNCKRHVSGRQCNQCQNGFYNLQELDPDG----CSPCNCNTSGTVDGDITCHQNSGQCKC 717
Query: 725 SHHTEGPSCERCLPGFYGNPFAGQADD--CQPCPCPGQSACTTIPESREVVCTHCPPGQR 782
+ G C+ C GF F +D C+PC C + C C +
Sbjct: 718 KANVIGLRCDHCNFGF---KFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC-ECKKEAK 773
Query: 783 GRRCEVCDDGFFGDPLGLFGHPQPCHQCQC--SGNVDPNAVGNCDPLSGHCLRCLHNTTG 840
G +C+ C + F+G + C C C +G++ P V C+ +G C+ C N G
Sbjct: 774 GLQCDTCRENFYGLDV------TNCKACDCDTAGSL-PGTV--CNAKTGQCI-CKPNVEG 823
Query: 841 DHCEHCQEG-FYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCS 899
C C EG FY L + C+PC+C G+++ + C+ TGQC C VT C+
Sbjct: 824 RQCNKCLEGNFY---LRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCN 880
Query: 900 RCYPGFFDLQPG--RGCRSCKCHPLGSQEDQ-CHPKTGQCTCRPGVTGQACDRCQLGFF- 955
+C P ++L + C+ C+C LG+ C P +GQC C P G+ C++CQ GF+
Sbjct: 881 QCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYI 940
Query: 956 -GFSIKGCRACRCSPLGAASAQCHE-NGTCVCRPG-FEGYKCDRCHDNFF-LTADGTHCQ 1011
+ GC C C GA + C+ G CVC+ G +CD+C D++F CQ
Sbjct: 941 SPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQ 1000
Query: 1012 QCPSCYALVKEEAAKLKARLTLTEGWLQGSDC 1043
C + E L + ++ GS C
Sbjct: 1001 PCNCHLSGALNETCHLVTGQCFCKQFVTGSKC 1032
Score = 173 bits (439), Expect = 1e-42
Identities = 116/372 (31%), Positives = 161/372 (43%), Gaps = 54/372 (14%)
Query: 675 CPTGYTGQFCESCAPGYKREMPQGGPYAS--CVPCTCNQHGT------CDPNTGICVCSH 726
C TG+ CE C + R++ P A C PC C+ GT CD G C C
Sbjct: 608 CEHNTTGRNCELCKDYFFRQVG-ADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKR 666
Query: 727 HTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTH------CPPG 780
H G C +C GFY N D C PC C T+ ++ C C
Sbjct: 667 HVSGRQCNQCQNGFY-NLQELDPDGCSPCNCN-----TSGTVDGDITCHQNSGQCKCKAN 720
Query: 781 QRGRRCEVCDDGF-----FGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCL 835
G RC+ C+ GF F D C CQC+ + N C+P SG C C
Sbjct: 721 VIGLRCDHCNFGFKFLRSFNDV--------GCEPCQCNLHGSVNKF--CNPHSGQC-ECK 769
Query: 836 HNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTA 895
G C+ C+E FYG + C C C GS+ + C+ TGQC C P+V
Sbjct: 770 KEAKGLQCDTCRENFYGLDVT-----NCKACDCDTAGSLPGTV-CNAKTGQCICKPNVEG 823
Query: 896 RDCSRCYPGFFDLQPGRG--CRSCKCHPLGSQEDQ--CHPKTGQCTCRPGVTGQACDRCQ 951
R C++C G F L+ C C C G+ C+ TGQC C+ GVTG C++C+
Sbjct: 824 RQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCE 883
Query: 952 LGFFGFSIKG---CRACRCSPLGAASAQCHE--NGTCVCRPGFEGYKCDRCHDNFFLT-A 1005
+ +I C+ C C LG + +G C+C P +G +C++C F+++
Sbjct: 884 PHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPG 943
Query: 1006 DGTHCQQCPSCY 1017
+ T C C SC+
Sbjct: 944 NATGCLPC-SCH 954
Score = 170 bits (430), Expect = 1e-41
Identities = 122/382 (31%), Positives = 168/382 (43%), Gaps = 58/382 (15%)
Query: 672 ICSCPTGYTGQFCESCAPGYKREMPQGGP--YA-SCVPCTCNQHG-------TCDP---- 717
+CS + G C+ C P Y + + G YA +C PC CN H + DP
Sbjct: 537 LCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFE 596
Query: 718 ----NTGIC-VCSHHTEGPSCERCLPGFYGNPFAGQA--DDCQPCPCPGQSACTTIPESR 770
G+C C H+T G +CE C F+ A + D C+PC C T +
Sbjct: 597 HFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCD-----TVGTRNG 651
Query: 771 EVVC------THCPPGQRGRRCEVCDDGFFG----DPLGLFGHPQPCHQCQCSGNVDPNA 820
++C +C GR+C C +GF+ DP G PC+ C SG VD +
Sbjct: 652 SILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGC----SPCN-CNTSGTVDGDI 706
Query: 821 VGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPC 880
C SG C +C N G C+HC GF L C PC C+ GSV++ C
Sbjct: 707 --TCHQNSGQC-KCKANVIGLRCDHCNFGF--KFLRSFNDVGCEPCQCNLHGSVNKF--C 759
Query: 881 DPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQ-CHPKTGQCTCR 939
+P +GQC C C C F+ L C++C C GS C+ KTGQC C+
Sbjct: 760 NPHSGQCECKKEAKGLQCDTCRENFYGLDV-TNCKACDCDTAGSLPGTVCNAKTGQCICK 818
Query: 940 PGVTGQACDRCQLGFFGFSIKG---CRACRCSPLGA--ASAQCHEN-GTCVCRPGFEGYK 993
P V G+ C++C G F C C C G S C+++ G C C+ G G +
Sbjct: 819 PNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLR 878
Query: 994 CDRCHDN-FFLTADG-THCQQC 1013
C++C + + LT D HCQ C
Sbjct: 879 CNQCEPHRYNLTIDNFQHCQMC 900
Score = 165 bits (418), Expect = 3e-40
Identities = 101/309 (32%), Positives = 139/309 (44%), Gaps = 32/309 (10%)
Query: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT-----CDPNTGICVCSHH 727
C C G C++C RE G +C C C+ G+ C+ TG C+C +
Sbjct: 766 CECKKEAKGLQCDTC-----RENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPN 820
Query: 728 TEGPSCERCLPG-FY---GNPFAGQADDCQPCPCPGQSACT-TIPESREVVCTHCPPGQR 782
EG C +CL G FY N F C PC C ++ ++ C G
Sbjct: 821 VEGRQCNKCLEGNFYLRQNNSFL-----CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVT 875
Query: 783 GRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDH 842
G RC C+ + + F H Q C +C G + P + CDP+SG CL C+ N G
Sbjct: 876 GLRCNQCEPHRYNLTIDNFQHCQMC-ECDSLGTL-PGTI--CDPISGQCL-CVPNRQGRR 930
Query: 843 CEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLP-HVTARDCSRC 901
C CQ GFY ++P A C+PCSCH G+V+ C+ +TGQC C + + C +C
Sbjct: 931 CNQCQPGFY---ISPGNATGCLPCSCHTTGAVNHI--CNSLTGQCVCQDASIAGQRCDQC 985
Query: 902 YPGFFDLQPGRG-CRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIK 960
+F P G C+ C CH G+ + CH TGQC C+ VTG CD C +
Sbjct: 986 KDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVN 1045
Query: 961 GCRACRCSP 969
C +P
Sbjct: 1046 NLLGCSKTP 1054
Score = 125 bits (315), Expect = 2e-28
Identities = 79/285 (27%), Positives = 117/285 (41%), Gaps = 83/285 (29%)
Query: 271 CKCNGHASECGPDVA------------GQLACRCQHNTTGTDCERCLPFFQDRPWARGTA 318
C+CN H+ C +++ G + C+HNTTG +CE C +F + A
Sbjct: 575 CQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGA--DP 632
Query: 319 EAAHECLPCNCSG---RSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWD 375
A C PC+C R+ D+ GG+C+ C+ H +G C +CQ FY+
Sbjct: 633 SAIDVCKPCDCDTVGTRNGSILCDQI-------GGQCN-CKRHVSGRQCNQCQNGFYNLQ 684
Query: 376 PRMP--CQPCDCQSAGSLH--------------------LQCDD---------------- 397
P C PC+C ++G++ L+CD
Sbjct: 685 ELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGC 744
Query: 398 ------------------TGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD 439
+G C CK G +CD C F+ L C+ C C+ AGSL
Sbjct: 745 EPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLP 804
Query: 440 --TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
C+ ++G+C CK NVEG C++C G F L+ +N C C C
Sbjct: 805 GTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849
Score = 124 bits (311), Expect = 7e-28
Identities = 77/239 (32%), Positives = 111/239 (46%), Gaps = 25/239 (10%)
Query: 256 QSYYYAVSDFSVGG--RCKCNGHASECGPDVAGQLA--CRCQHNTTGTDCERCLPFFQDR 311
Q+ +Y + + G C CN + G Q + C+C+ N G C+ C F+
Sbjct: 677 QNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFK-- 734
Query: 312 PWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENF 371
+ R + C PC C+ F H G+C C+ G C+ C+ENF
Sbjct: 735 -FLRSFNDVG--CEPCQCNLHGSVNKF------CNPHSGQCE-CKKEAKGLQCDTCRENF 784
Query: 372 YHWDPRMPCQPCDCQSAGSLH-LQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGG--- 426
Y D C+ CDC +AGSL C+ TG C CKP V G +C++CL G L +
Sbjct: 785 YGLDVTN-CKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFL 843
Query: 427 CRPCTCNPAGSLD---TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
C PC C+ G+++ C+ +G+CPCK V G C++C P +NL N C C C
Sbjct: 844 CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC 902
Score = 109 bits (272), Expect = 2e-23
Identities = 73/228 (32%), Positives = 107/228 (46%), Gaps = 35/228 (15%)
Query: 271 CKCNGHASE---CGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPC 327
C+CN H S C P +GQ C C+ G C+ C F C C
Sbjct: 747 CQCNLHGSVNKFCNPH-SGQ--CECKKEAKGLQCDTCRENFYGLD--------VTNCKAC 795
Query: 328 NC--SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQE-NFY-HWDPRMPCQPC 383
+C +G + + G+C C+ + G C +C E NFY + C PC
Sbjct: 796 DCDTAGSLPGTVCNAKT-------GQCI-CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPC 847
Query: 384 DCQSAGSLH--LQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGG---CRPCTCNPAGS 437
+C G+++ L C+ TG C CK VTG +C++C P ++L+ C+ C C+ G+
Sbjct: 848 NCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGT 907
Query: 438 L--DTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCY 483
L CDP SG+C C N +G C++C+PG F + P N GC C C+
Sbjct: 908 LPGTICDPISGQCLCVPNRQGRRCNQCQPG-FYISPGNATGCLPCSCH 954
Score = 95.5 bits (236), Expect = 4e-19
Identities = 59/195 (30%), Positives = 89/195 (45%), Gaps = 17/195 (8%)
Query: 290 CRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHG 349
C C+ TG C +C P + T + C C C T +
Sbjct: 868 CPCKLGVTGLRCNQCEPHRYNL-----TIDNFQHCQMCECDSLG---TLPGTICDPIS-- 917
Query: 350 GRCHHCRDHTAGPHCERCQENFYHWDPRMP-CQPCDCQSAGSLHLQCDD-TGTCACKP-T 406
G+C C + G C +CQ FY C PC C + G+++ C+ TG C C+ +
Sbjct: 918 GQCL-CVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDAS 976
Query: 407 VTGWKCDRCLPGFHSLSE--GGCRPCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCDRCR 463
+ G +CD+C + G C+PC C+ +G+L +TC +G+C CK+ V G+ CD C
Sbjct: 977 IAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACV 1036
Query: 464 PGTFNLQPHNPAGCS 478
P +L +N GCS
Sbjct: 1037 PSASHLDVNNLLGCS 1051
Score = 87.0 bits (214), Expect = 1e-16
Identities = 59/184 (32%), Positives = 86/184 (46%), Gaps = 23/184 (12%)
Query: 258 YYYAVSDFSVGGRCKCNG----HASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPW 313
Y + +F C+C+ + C P ++GQ C C N G C +C P F P
Sbjct: 887 YNLTIDNFQHCQMCECDSLGTLPGTICDP-ISGQ--CLCVPNRQGRRCNQCQPGFYISP- 942
Query: 314 ARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHT-AGPHCERCQENFY 372
G A CLPC+C L G+C C+D + AG C++C+++++
Sbjct: 943 --GNATG---CLPCSCHTTGAVNHICNSLT------GQCV-CQDASIAGQRCDQCKDHYF 990
Query: 373 HWDPRMP-CQPCDCQSAGSLHLQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPC 430
+DP+ CQPC+C +G+L+ C TG C CK VTG KCD C+P L C
Sbjct: 991 GFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050
Query: 431 TCNP 434
+ P
Sbjct: 1051 SKTP 1054
Score = 39.7 bits (91), Expect = 0.023
Identities = 26/70 (37%), Positives = 30/70 (42%), Gaps = 13/70 (18%)
Query: 430 CTCNPAGSLDTCDPRSG--RCPCKEN--VEGNLCDRCRPGTFNLQPHNPA------GCSS 479
C C+ G D CD S RC C + EG CDRC P +N +P C
Sbjct: 518 CQCH--GHADNCDTTSQPYRCLCSQESFTEGLHCDRCLP-LYNDKPFRQGDQVYAFNCKP 574
Query: 480 CFCYGHSKVC 489
C C HSK C
Sbjct: 575 CQCNSHSKSC 584
>gi|164414431 netrin G1 isoform 1 [Homo sapiens]
Length = 539
Score = 212 bits (540), Expect = 2e-54
Identities = 146/449 (32%), Positives = 206/449 (45%), Gaps = 56/449 (12%)
Query: 53 TCGSPPEDFCPHVGAAGAGAHCQR-CDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFG 111
TCG PPE FC A G C CDA+ P+ H + DF + ST+WQS +
Sbjct: 71 TCGDPPETFC----AMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWK-- 124
Query: 112 VQYPT--SVNITLRLGKAYEIT-YVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQ 168
+YP VNITL K E+T + + F + RP+ + K W+PYQ+Y+ C
Sbjct: 125 -EYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCL 183
Query: 169 KTYGR-PEGQYLRPGEDERVAFCTSEFSDISPLSGGNVAFST-----------LEGRPSA 216
+ P+ CT E+S + + F L S
Sbjct: 184 DAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASL 243
Query: 217 YN-FEESPGLQEWVTSTELLISLDRLNTFGDDIFKDPKVLQSYYYAVSDFSVGGRCKCNG 275
Y + + L+++ T T+L I L L +IF D L Y+YA+SD V GRCKCN
Sbjct: 244 YGQLDTTKKLRDFFTVTDLRIRL--LRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNL 301
Query: 276 HASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGT-----AEAAHECLP---- 326
HA+ C D + +L C C+HNTTG DC +C +Q RPW+ G+ A+ C+P
Sbjct: 302 HATVCVYDNS-KLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
Query: 327 ---CNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYH-----WDPRM 378
C C G S C++ +L + C C+ +T G HCE C+ ++ D
Sbjct: 361 IGNCECFGHSNRCSYI-DLLNTV----ICVSCKHNTRGQHCELCRLGYFRNASAQLDDEN 415
Query: 379 PCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCN----P 434
C C C GS+H +C+ +G C CK TG KCD CLPG + GC+P C+
Sbjct: 416 VCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPG--NSWHYGCQPNVCDNELLH 473
Query: 435 AGSLDTCDPRSGRCPCKENVEGNLCDRCR 463
+ TC + RC C G LC++ R
Sbjct: 474 CQNGGTCH-NNVRCLCPAAYTGILCEKLR 501
Score = 82.8 bits (203), Expect = 2e-15
Identities = 71/255 (27%), Positives = 93/255 (36%), Gaps = 63/255 (24%)
Query: 707 CTCNQHGTC---DPNTGICVCSHHTEGPSCERCLPGFYGNPFA---------GQADDCQP 754
C CN H T D + C C H+T GP C +C + G P++ G A+ C P
Sbjct: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
Query: 755 -------CPCPGQS-ACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQP 806
C C G S C+ I V+C C RG+ CE+C G+F +
Sbjct: 357 SISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENV 416
Query: 807 CHQCQCS--GNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEG---FYGSALAPRPAD 861
C +C C+ G++ G SG C C TTG C+ C G YG
Sbjct: 417 CIECYCNPLGSIHDRCNG-----SGFC-ECKTGTTGPKCDECLPGNSWHYG--------- 461
Query: 862 KCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARD-CSRCYPGFFDLQPGRGCRSCKCH 920
C P +E + C G C H R C Y G C +C
Sbjct: 462 ------CQPNVCDNELLHCQN-GGTC----HNNVRCLCPAAYTGIL-------CEKLRCE 503
Query: 921 PLGSQEDQCHPKTGQ 935
GS C +GQ
Sbjct: 504 EAGS----CGSDSGQ 514
Score = 79.7 bits (195), Expect = 2e-14
Identities = 56/193 (29%), Positives = 76/193 (39%), Gaps = 32/193 (16%)
Query: 834 CLHNTTGDHCEHCQEGFYGSALAPR---PADKCMPCSCHPQGSVSEQMPCDPVTGQCS-- 888
C HNTTG C C++ + G +P P K +C P S C + +CS
Sbjct: 317 CEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYI 376
Query: 889 ----------CLPHVTARDCSRCYPGFF-----DLQPGRGCRSCKCHPLGSQEDQCHPKT 933
C + + C C G+F L C C C+PLGS D+C+ +
Sbjct: 377 DLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNG-S 435
Query: 934 GQCTCRPGVTGQACDRCQLG---FFGFSIKGC--RACRCSPLGAASAQCHENGTCVCRPG 988
G C C+ G TG CD C G +G C C G CH N C+C
Sbjct: 436 GFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGT----CHNNVRCLCPAA 491
Query: 989 FEGYKCD--RCHD 999
+ G C+ RC +
Sbjct: 492 YTGILCEKLRCEE 504
Score = 64.3 bits (155), Expect = 9e-10
Identities = 66/244 (27%), Positives = 91/244 (37%), Gaps = 49/244 (20%)
Query: 327 CNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYH--WDPRM------ 378
C C+ + C +D C +T GP C +C++N+ W P
Sbjct: 297 CKCNLHATVCVYDNSKLTC--------ECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPK 348
Query: 379 ----PCQP-------CDC--QSAGSLHLQCDDTGTC-ACKPTVTGWKCDRCLPGFHSLS- 423
C P C+C S ++ +T C +CK G C+ C G+ +
Sbjct: 349 GTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNAS 408
Query: 424 -----EGGCRPCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCDRCRPGT---FNLQPHNP 474
E C C CNP GS+ D C+ SG C CK G CD C PG + QP N
Sbjct: 409 AQLDDENVCIECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPGNSWHYGCQP-NV 466
Query: 475 AGCSSCFCYG----HSKV-CASTAQFQVHHILSDFHQGAEGWWARSVGGSEHPPQWSPNG 529
C H+ V C A + IL + + E S G PP SP
Sbjct: 467 CDNELLHCQNGGTCHNNVRCLCPAAYT--GILCEKLRCEEAGSCGSDSGQGAPPHGSPAL 524
Query: 530 VLLS 533
+LL+
Sbjct: 525 LLLT 528
Score = 41.6 bits (96), Expect = 0.006
Identities = 43/161 (26%), Positives = 53/161 (32%), Gaps = 48/161 (29%)
Query: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYA--SCVPCTCNQHGTCDPNT---GICV---- 723
C C TG C C Y QG P++ S +P TC P+ G C
Sbjct: 315 CECEHNTTGPDCGKCKKNY-----QGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGH 369
Query: 724 -----------------CSHHTEGPSCERCLPGFYGNPFAGQADD--------CQPC--- 755
C H+T G CE C G++ N A Q DD C P
Sbjct: 370 SNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASA-QLDDENVCIECYCNPLGSI 428
Query: 756 --PCPGQSACTTIPESREVVCTHCPPGQR---GRRCEVCDD 791
C G C + C C PG G + VCD+
Sbjct: 429 HDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDN 469
Score = 36.6 bits (83), Expect = 0.20
Identities = 22/70 (31%), Positives = 27/70 (38%), Gaps = 15/70 (21%)
Query: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQH-------GTCDPNTGICVCS 725
C C TG TG C+ C PG + C P C+ GTC N C+C
Sbjct: 438 CECKTGTTGPKCDECLPG-------NSWHYGCQPNVCDNELLHCQNGGTCHNNVR-CLCP 489
Query: 726 HHTEGPSCER 735
G CE+
Sbjct: 490 AAYTGILCEK 499
>gi|190014607 netrin G2 [Homo sapiens]
Length = 530
Score = 197 bits (500), Expect = 9e-50
Identities = 142/452 (31%), Positives = 199/452 (44%), Gaps = 58/452 (12%)
Query: 53 TCGSPPEDFCPHVGAAGAGAHCQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGV 112
TCG PPE FC H CDA++P H + D + +T+WQS + +
Sbjct: 60 TCGDPPERFCSHENPYLCS---NECDASNPDLAHPPRLMFDKEEEGLATYWQSITWS--- 113
Query: 113 QYPTSV--NITLRLGKAYEITY-VRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQK 169
+YP+ + NITL K E+T V + F RP + K W+PYQFY+ C +
Sbjct: 114 RYPSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCME 173
Query: 170 TYGRP--EGQYLRPGEDERVAFCTSEFSD-ISPLSGGNVAFST-----------LEGRPS 215
+G + + RV CT E+S +V F L +
Sbjct: 174 AFGMSARRARDMSSSSAHRV-LCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDN 232
Query: 216 AYN-FEESPGLQEWVTSTELLISLDRLNTFGDDIFKDPKVLQSYYYAVSDFSVGGRCKCN 274
Y E + GL+E+ T T+L + L R G + ++ L Y+YA+S+ V GRCKCN
Sbjct: 233 LYTRLESAKGLKEFFTLTDLRMRLLRPALGGTYVQREN--LYKYFYAISNIEVIGRCKCN 290
Query: 275 GHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLP-------- 326
HA+ C G L C C+HNTTG DC +C F+ R W G+ P
Sbjct: 291 LHANLCSMR-EGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGS 349
Query: 327 ---CNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYH-----WDPRM 378
C C G S C++ L T C C+ +T G HC+ C+ +Y D
Sbjct: 350 FGNCECYGHSNRCSYIDFLNVVT-----CVSCKHNTRGQHCQHCRLGYYRNGSAELDDEN 404
Query: 379 PCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSL 438
C C+C GS+H +C++TG C C+ G KCD CLP + GC P C+ L
Sbjct: 405 VCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHY--WRQGCYPNVCDDDQLL 462
Query: 439 ----DTCDPRSGRCPCKENVEGNLCD--RCRP 464
TC ++ RC C G C+ RC P
Sbjct: 463 CQNGGTC-LQNQRCACPRGYTGVRCEQPRCDP 493
Score = 84.7 bits (208), Expect = 6e-16
Identities = 69/255 (27%), Positives = 97/255 (38%), Gaps = 65/255 (25%)
Query: 707 CTCNQHGT-CDPNTGI--CVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSAC 763
C CN H C G C C H+T GP C +C F + +A P P +AC
Sbjct: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSW--RAGSYLPLPHGSPNAC 344
Query: 764 TTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGN 823
T G FG+ C+C G+ N
Sbjct: 345 ATA--------------------------------GSFGN------CECYGH--SNRCSY 364
Query: 824 CDPLSG-HCLRCLHNTTGDHCEHCQEGFYGSALAPRPADK-CMPCSCHPQGSVSEQMPCD 881
D L+ C+ C HNT G HC+HC+ G+Y + A + C+ C+C+ GSV ++ C+
Sbjct: 365 IDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDR--CN 422
Query: 882 PVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTG------- 934
TG C C C C P + Q C+P +DQ + G
Sbjct: 423 E-TGFCECREGAAGPKCDDCLPTHYWRQ--------GCYPNVCDDDQLLCQNGGTCLQNQ 473
Query: 935 QCTCRPGVTGQACDR 949
+C C G TG C++
Sbjct: 474 RCACPRGYTGVRCEQ 488
Score = 76.6 bits (187), Expect = 2e-13
Identities = 53/203 (26%), Positives = 78/203 (38%), Gaps = 25/203 (12%)
Query: 834 CLHNTTGDHCEHCQEGF--------------YGSALAPRPADKCMPCSCHPQGSVSEQMP 879
C HNTTG C C++ F +GS A A C C+ + +
Sbjct: 307 CEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYID 366
Query: 880 CDPVTGQCSCLPHVTARDCSRCYPGFF-----DLQPGRGCRSCKCHPLGSQEDQCHPKTG 934
V SC + + C C G++ +L C C C+ +GS D+C+ +TG
Sbjct: 367 FLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETG 425
Query: 935 QCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSP---LGAASAQCHENGTCVCRPGFEG 991
C CR G G CD C + +GC C L C +N C C G+ G
Sbjct: 426 FCECREGAAGPKCDDCLPTHYWR--QGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTG 483
Query: 992 YKCDRCHDNFFLTADGTHCQQCP 1014
+C++ + G C + P
Sbjct: 484 VRCEQPRCDPADDDGGLDCDRAP 506
Score = 58.5 bits (140), Expect = 5e-08
Identities = 42/128 (32%), Positives = 49/128 (38%), Gaps = 21/128 (16%)
Query: 670 VEICSCPTGYTGQFCESCAPGYKRE-MPQGGPYASCVPCTCNQ----HGTCDPNTGICVC 724
V SC GQ C+ C GY R + C+ C CNQ H C+ TG C C
Sbjct: 371 VTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFCEC 429
Query: 725 SHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPG-----QSACTTIPESREVVCTHCPP 779
GP C+ CLP Y C P C Q+ T + R C CP
Sbjct: 430 REGAAGPKCDDCLPTHYWR------QGCYPNVCDDDQLLCQNGGTCLQNQR---CA-CPR 479
Query: 780 GQRGRRCE 787
G G RCE
Sbjct: 480 GYTGVRCE 487
Score = 47.0 bits (110), Expect = 1e-04
Identities = 37/139 (26%), Positives = 47/139 (33%), Gaps = 24/139 (17%)
Query: 673 CSCPTGYTGQFCESCAPGYKRE---------MPQGGPYASCVP-----CTCNQHGT-CDP 717
C C TG C C ++ +P G P A C C H C
Sbjct: 305 CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSY 364
Query: 718 ----NTGICV-CSHHTEGPSCERCLPGFYGNPFAGQADD--CQPCPCPGQSACTTIPESR 770
N CV C H+T G C+ C G+Y N A D+ C C C +
Sbjct: 365 IDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC--NQIGSVHDRCN 422
Query: 771 EVVCTHCPPGQRGRRCEVC 789
E C G G +C+ C
Sbjct: 423 ETGFCECREGAAGPKCDDC 441
Score = 40.8 bits (94), Expect = 0.010
Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 16/77 (20%)
Query: 430 CTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRC---------RPGTFNLQPH-NPAGCSS 479
C CN +L + S +C C+ N G C +C R G++ PH +P C++
Sbjct: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346
Query: 480 ------CFCYGHSKVCA 490
C CYGHS C+
Sbjct: 347 AGSFGNCECYGHSNRCS 363
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 164 bits (416), Expect = 5e-40
Identities = 124/336 (36%), Positives = 152/336 (45%), Gaps = 74/336 (22%)
Query: 673 CSCPTGYTGQFCES-CAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVCSHHTEGP 731
C C G+TG C+S C PG + GP S V C+C G+C P G C C+ GP
Sbjct: 551 CCCLAGWTGIRCDSTCPPG------RWGPNCS-VSCSCENGGSCSPEDGSCECAPGFRGP 603
Query: 732 SCER-CLPGFYGNPFAGQADDCQPCPCPGQSA--CTTIPESREVVCTHCPPGQRGRRC-E 787
C+R C PGFYG+ A QPCP S+ C I +C C PG G C +
Sbjct: 604 LCQRICPPGFYGHGCA------QPCPLCVHSSRPCHHI----SGIC-ECLPGFSGALCNQ 652
Query: 788 VCDDGFFGDPLGLFGHPQPCHQ-CQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHC-EH 845
VC G+FG Q C Q C C+ N G C P+ G C +C G C +
Sbjct: 653 VCAGGYFG---------QDCAQLCSCANN------GTCSPIDGSC-QCFPGWIGKDCSQA 696
Query: 846 CQEGFYGSALAPRPADKCM-PCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCS-RCYP 903
C GF+G A C CSCH S C G C C P T C+ RC
Sbjct: 697 CPPGFWGPA--------CFHACSCHNGAS------CSAEDGACHCTPGWTGLFCTQRCPA 742
Query: 904 GFFDLQPGRGC-RSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACD-RCQLGFFGFSIKG 961
FF G+ C R C+C S C +G+CTCR G TGQ C+ RC G FG+ G
Sbjct: 743 AFF----GKDCGRVCQCQNGAS----CDHISGKCTCRTGFTGQHCEQRCAPGTFGY---G 791
Query: 962 C-RACRCSPLGAASAQCHENGTCVCRPGFEGYKCDR 996
C + C C H GTC C PGF+G +CD+
Sbjct: 792 CQQLCECMNNSTCD---HVTGTCYCSPGFKGIRCDQ 824
Score = 152 bits (383), Expect = 3e-36
Identities = 128/394 (32%), Positives = 151/394 (38%), Gaps = 86/394 (21%)
Query: 673 CSCPTGYTGQFCES-CAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVCSHHTEGP 731
C C G+ G CE CAPG + Q +PC C +CDP G C+C+ G
Sbjct: 161 CVCAAGFRGWRCEELCAPGTHGKGCQ-------LPCQCRHGASCDPRAGECLCAPGYTGV 213
Query: 732 SCER-CLPGFYGNPFAGQADDCQ-PCPCPGQSACTTIPESREVVCTHCPPGQRGRRC-EV 788
CE C PG +G C+ CPC C I C CPPG G C +
Sbjct: 214 YCEELCPPGSHG-------AHCELRCPCQNGGTCHHITGE----CA-CPPGWTGAVCAQP 261
Query: 789 CDDGFFGDPLGLFGHPQPCHQ-CQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHC-EHC 846
C G FG Q C Q C C G CD ++G C C GD C E C
Sbjct: 262 CPPGTFG---------QNCSQDCPCHHG------GQCDHVTGQC-HCTAGYMGDRCQEEC 305
Query: 847 QEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSR--CYPG 904
G +G + C CH G C P TG C C P C C G
Sbjct: 306 PFGSFGFQCSQH-------CDCHNGGQ------CSPTTGACECEPGYKGPRCQERLCPEG 352
Query: 905 FFDLQPGRGCR-SCKCHPLGSQEDQCHPKTGQCTCRPGVTGQAC-DRCQLGFFGFSIKGC 962
G GC C C CHP TG CTC+PG +G C + C +G++G GC
Sbjct: 353 LH----GPGCTLPCPCD--ADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYG---DGC 403
Query: 963 R-ACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPS-CYAL 1019
+ C C A CH G C C PGF G C A GT+ C S C
Sbjct: 404 QLPCTCQ----NGADCHSITGGCTCAPGFMGEVC------AVSCAAGTYGPNCSSICSCN 453
Query: 1020 VKEEAAKLKARLTLTEGWLQGSDCGSP-----WG 1048
+ + T EGW QG DC P WG
Sbjct: 454 NGGTCSPVDGSCTCKEGW-QGLDCTLPCPSGTWG 486
Score = 146 bits (368), Expect = 2e-34
Identities = 134/423 (31%), Positives = 161/423 (38%), Gaps = 97/423 (22%)
Query: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASC-VPCTCNQHGT--CDPNTGICVCSHHTE 729
C C GY G C+ +R P+G C +PC C+ T C P TG C C
Sbjct: 333 CECEPGYKGPRCQ------ERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWS 386
Query: 730 GPSC-ERCLPGFYGNPFAGQADDCQ-PCPCPGQSACTTIPESREVVCTHCPPGQRGRRCE 787
G C E C G+YG D CQ PC C + C +I CT C PG G C
Sbjct: 387 GHHCNESCPVGYYG-------DGCQLPCTCQNGADCHSITGG----CT-CAPGFMGEVCA 434
Query: 788 V-CDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHC------------LRC 834
V C G +G P C C+ G C P+ G C L C
Sbjct: 435 VSCAAGTYG--------PNCSSICSCNNG------GTCSPVDGSCTCKEGWQGLDCTLPC 480
Query: 835 LHNTTGDHCEHCQEGFYGSALAPRPA----------DKC-MPC-------SCHPQGSVSE 876
T G +C G+A +P D C +PC +C S
Sbjct: 481 PSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSH 540
Query: 877 QMPCDPVTGQCSCLPHVTARDC-SRCYPGFFDLQPGRGCR-SCKCHPLGSQEDQCHPKTG 934
CDPVTG C CL T C S C PG + G C SC C GS C P+ G
Sbjct: 541 ADGCDPVTGHCCCLAGWTGIRCDSTCPPGRW----GPNCSVSCSCENGGS----CSPEDG 592
Query: 935 QCTCRPGVTGQACDR-CQLGFFGFSIKGCRACRCSPLGAASAQCHE-NGTCVCRPGFEGY 992
C C PG G C R C GF+G GC A C +S CH +G C C PGF G
Sbjct: 593 SCECAPGFRGPLCQRICPPGFYG---HGC-AQPCPLCVHSSRPCHHISGICECLPGFSGA 648
Query: 993 KCDR-CHDNFFLTADGTHCQQCPSCYALVKEEAAKLKARLTLTEGWLQGSDCGSP----- 1046
C++ C +F G C Q SC + + GW+ G DC
Sbjct: 649 LCNQVCAGGYF----GQDCAQLCSC--ANNGTCSPIDGSCQCFPGWI-GKDCSQACPPGF 701
Query: 1047 WGP 1049
WGP
Sbjct: 702 WGP 704
Score = 145 bits (367), Expect = 2e-34
Identities = 114/353 (32%), Positives = 149/353 (42%), Gaps = 69/353 (19%)
Query: 673 CSCPTGYTGQFCE-SCAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVCSHHTEGP 731
C+C G+ G+ C SCA G GP S + C+CN GTC P G C C +G
Sbjct: 422 CTCAPGFMGEVCAVSCAAGTY------GPNCSSI-CSCNNGGTCSPVDGSCTCKEGWQGL 474
Query: 732 SCER-CLPGFYGNPFAGQADDC-QPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEV- 788
C C G +G +C + C C +AC+ I S C+ C PG G CE+
Sbjct: 475 DCTLPCPSGTWGL-------NCNESCTCANGAACSPIDGS----CS-CTPGWLGDTCELP 522
Query: 789 CDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEH-CQ 847
C DG FG CS + D + CDP++GHC CL TG C+ C
Sbjct: 523 CPDGTFG--------------LNCSEHCDCSHADGCDPVTGHCC-CLAGWTGIRCDSTCP 567
Query: 848 EGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSR-CYPGFF 906
G +G + + CSC GS C P G C C P C R C PGF+
Sbjct: 568 PGRWGPNCS-------VSCSCENGGS------CSPEDGSCECAPGFRGPLCQRICPPGFY 614
Query: 907 DLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDR-CQLGFFGFSIKGCRAC 965
G GC C CH +G C C PG +G C++ C G+FG + C
Sbjct: 615 ----GHGCAQ-PCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDC--AQLC 667
Query: 966 RCSPLGAASAQCHENGTCVCRPGFEGYKCDR-CHDNFFLTADGTHCQQCPSCY 1017
C+ G S +G+C C PG+ G C + C F+ G C SC+
Sbjct: 668 SCANNGTCSPI---DGSCQCFPGWIGKDCSQACPPGFW----GPACFHACSCH 713
Score = 91.3 bits (225), Expect = 7e-18
Identities = 75/244 (30%), Positives = 91/244 (37%), Gaps = 52/244 (21%)
Query: 672 ICSCPTGYTGQFCES-CAPGYKREMPQGGPYASCVP-CTCNQHGTCDPNTGICVCSHHTE 729
IC C G++G C CA GY + C C+C +GTC P G C C
Sbjct: 638 ICECLPGFSGALCNQVCAGGYFGQ--------DCAQLCSCANNGTCSPIDGSCQCFPGWI 689
Query: 730 GPSCER-CLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRC-E 787
G C + C PGF+G P A C C ++C S E HC PG G C +
Sbjct: 690 GKDCSQACPPGFWG-PACFHA-----CSCHNGASC-----SAEDGACHCTPGWTGLFCTQ 738
Query: 788 VCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEH-C 846
C FFG G CQC +CD +SG C C TG HCE C
Sbjct: 739 RCPAAFFGKDCG--------RVCQCQNGA------SCDHISGKCT-CRTGFTGQHCEQRC 783
Query: 847 QEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFF 906
G +G C C + CD VTG C C P C +
Sbjct: 784 APGTFGYGCQQL-------CECMNNST------CDHVTGTCYCSPGFKGIRCDQAALMME 830
Query: 907 DLQP 910
+L P
Sbjct: 831 ELNP 834
Score = 72.0 bits (175), Expect = 4e-12
Identities = 67/238 (28%), Positives = 89/238 (37%), Gaps = 45/238 (18%)
Query: 268 GGRCKCNGHASECGPDVAGQLACR-CQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLP 326
GG C C P G + + C T G +C QD P G + H
Sbjct: 237 GGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCS------QDCPCHHG-GQCDHVTGQ 289
Query: 327 CNCSGR------SEECTFDRELFRSTGH-----GGRCH------HCRDHTAGPHCER--C 367
C+C+ EEC F F+ + H GG+C C GP C+ C
Sbjct: 290 CHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLC 349
Query: 368 QENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLP-GFHSLSEGG 426
E + +PC PCD + S H TG C C+P +G C+ P G++ G
Sbjct: 350 PEGLHGPGCTLPC-PCDADNTISCH---PVTGACTCQPGWSGHHCNESCPVGYYG---DG 402
Query: 427 CR-PCTCNPAGSLDTCDPRSGRCPCKENVEGNLCD-RCRPGTFNLQPHNPAGCSSCFC 482
C+ PCTC C +G C C G +C C GT+ P S C C
Sbjct: 403 CQLPCTCQNGAD---CHSITGGCTCAPGFMGEVCAVSCAAGTY-----GPNCSSICSC 452
Score = 71.2 bits (173), Expect = 7e-12
Identities = 55/156 (35%), Positives = 70/156 (44%), Gaps = 28/156 (17%)
Query: 316 GTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCER-CQENFYHW 374
G E+ C+P C+ EEC R + T CH C GP C C + HW
Sbjct: 91 GYYESGDFCIPL-CT---EECVHGRCVSPDT-----CH-CEPGWGGPDCSSGCDSD--HW 138
Query: 375 DPRMPCQPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDR-CLPGFHSLSEGGCR-PCT 431
P + C CQ+ G+L C+ TG C C GW+C+ C PG H GC+ PC
Sbjct: 139 GPHCSNR-CQCQN-GAL---CNPITGACVCAAGFRGWRCEELCAPGTHGK---GCQLPCQ 190
Query: 432 CNPAGSLDTCDPRSGRCPCKENVEGNLCDR-CRPGT 466
C S CDPR+G C C G C+ C PG+
Sbjct: 191 CRHGAS---CDPRAGECLCAPGYTGVYCEELCPPGS 223
Score = 65.5 bits (158), Expect = 4e-10
Identities = 70/243 (28%), Positives = 82/243 (33%), Gaps = 46/243 (18%)
Query: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCER-CLPFFQDRPWARGTAEAAHECLPCNC 329
C C S C P+ +C C G C+R C P F A+ H PC+
Sbjct: 579 CSCENGGS-CSPEDG---SCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHH 634
Query: 330 SGRSEECT--FDRELFRSTGHGGR--------CHHCRDHTAGPHCERCQENFYHW---DP 376
EC F L GG C + T P CQ F W D
Sbjct: 635 ISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQ-CFPGWIGKDC 693
Query: 377 RMPCQP----------CDCQSAGSLHLQCDDTGTCACKPTVTGWKC-DRCLPGFHSLSEG 425
C P C C + S + G C C P TG C RC F G
Sbjct: 694 SQACPPGFWGPACFHACSCHNGASCSAE---DGACHCTPGWTGLFCTQRCPAAFFGKDCG 750
Query: 426 GCRPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCD-RCRPGTFNLQPHNPAGCSS-CFCY 483
R C C S CD SG+C C+ G C+ RC PGTF GC C C
Sbjct: 751 --RVCQCQNGAS---CDHISGKCTCRTGFTGQHCEQRCAPGTFGY------GCQQLCECM 799
Query: 484 GHS 486
+S
Sbjct: 800 NNS 802
Score = 61.2 bits (147), Expect = 7e-09
Identities = 66/227 (29%), Positives = 80/227 (35%), Gaps = 45/227 (19%)
Query: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
C CN + C P V G +C C+ G DC P W E+ C C+
Sbjct: 450 CSCN-NGGTCSP-VDG--SCTCKEGWQGLDCTLPCP---SGTWGLNCNES------CTCA 496
Query: 331 GRSEECTFDRELFRSTGH-GGRCH-HCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSA 388
+ D + G G C C D T G +C + CDC A
Sbjct: 497 NGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCS---------------EHCDCSHA 541
Query: 389 GSLHLQCDD-TGTCACKPTVTGWKCDR-CLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSG 446
CD TG C C TG +CD C PG C+C GS C P G
Sbjct: 542 DG----CDPVTGHCCCLAGWTGIRCDSTCPPG--RWGPNCSVSCSCENGGS---CSPEDG 592
Query: 447 RCPCKENVEGNLCDR-CRPGTFN---LQPHNPAGCSSCFCYGHSKVC 489
C C G LC R C PG + QP SS C+ S +C
Sbjct: 593 SCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGIC 639
Score = 58.2 bits (139), Expect = 6e-08
Identities = 61/206 (29%), Positives = 80/206 (38%), Gaps = 41/206 (19%)
Query: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
C C + + C P + G +C+C G DC + P P G A H C N +
Sbjct: 667 CSCANNGT-CSP-IDG--SCQCFPGWIGKDCSQACP-----PGFWGPA-CFHACSCHNGA 716
Query: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHC-ERCQENFYHWDPRMPCQPCDCQSAG 389
S E G CH C G C +RC F+ D CQ CQ+
Sbjct: 717 SCSAE-------------DGACH-CTPGWTGLFCTQRCPAAFFGKDCGRVCQ---CQNGA 759
Query: 390 SLHLQCDD-TGTCACKPTVTGWKCD-RCLPGFHSLSEGGCRP-CTCNPAGSLDTCDPRSG 446
S CD +G C C+ TG C+ RC PG GC+ C C + TCD +G
Sbjct: 760 S----CDHISGKCTCRTGFTGQHCEQRCAPGTFGY---GCQQLCECM---NNSTCDHVTG 809
Query: 447 RCPCKENVEGNLCDRCRPGTFNLQPH 472
C C +G CD+ L P+
Sbjct: 810 TCYCSPGFKGIRCDQAALMMEELNPY 835
>gi|24308065 netrin 5 [Homo sapiens]
Length = 489
Score = 164 bits (415), Expect = 6e-40
Identities = 131/485 (27%), Positives = 174/485 (35%), Gaps = 149/485 (30%)
Query: 3 AAALLLGLALLAPRAAGAGMGACYDGAGRPQRCLPVFENAAFGRLAQASHTCGSPPEDFC 62
A LLLG A P CYD GRPQ CLP
Sbjct: 6 ALLLLLGQATADP---------CYDPQGRPQFCLP------------------------- 31
Query: 63 PHVGAAGAGAHCQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITL 122
P A A C + A P H G + + ++TL
Sbjct: 32 PVTQLAAVAASCPQACALSPGNH------------------------LGARETCNGSLTL 67
Query: 123 RLGKAYEITYVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPG 182
LG + +T V L+F T P + + + GPW + + RP
Sbjct: 68 ALGGPFLLTSVSLRFCTPGPPALILSAAWASGGPW----------RLLWHRP-------- 109
Query: 183 EDERVAFCTSEFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLN 242
A+ G P F +PG + V ++ L +
Sbjct: 110 -----------------------AWPGALGGPERVTFHSTPGPKATVAASHLRVE----- 141
Query: 243 TFGDDIFKDPKVLQSYYYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCE 302
FG ++ + GRC+C+GHA+ C A C C+H+TTG CE
Sbjct: 142 -FGGQA------------GLAAAGLRGRCQCHGHAARCAAR-ARPPRCHCRHHTTGPGCE 187
Query: 303 RCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTG--HGGRCHHCRDHTA 360
C P +D PW T H CLPC+C+ + C F+ ELFR +G GG C CR HTA
Sbjct: 188 SCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTA 247
Query: 361 GPHCERCQENFYHWDPRMP------CQPCDCQSAGSLHLQCDDT-GTCACKPTVTGWKCD 413
G HC CQ F+ DP P C+ C C G+ C+ T G C CK VTG C+
Sbjct: 248 GRHCHYCQPGFWR-DPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCN 306
Query: 414 RCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHN 473
RC PG+ RS R PC+ E PG ++ P
Sbjct: 307 RCGPGYQ---------------------QSRSPRMPCQRIPEATTTLATTPGAYSSDPQC 345
Query: 474 PAGCS 478
C+
Sbjct: 346 QNYCN 350
Score = 95.9 bits (237), Expect = 3e-19
Identities = 57/161 (35%), Positives = 75/161 (46%), Gaps = 19/161 (11%)
Query: 809 QCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYG---SALAPRPADKCMP 865
+CQC G+ A P C C H+TTG CE C+ PR C+P
Sbjct: 156 RCQCHGHAARCAARARPP---RC-HCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLP 211
Query: 866 CSCHPQG------SVSEQMPCDPVTGQCS-CLPHVTARDCSRCYPGFF--DLQP---GRG 913
CSC+ S ++ G C C H R C C PGF+ QP R
Sbjct: 212 CSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRA 271
Query: 914 CRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGF 954
CR+C+CHP+G+ C+ +GQCTC+ GVTG C+RC G+
Sbjct: 272 CRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
Score = 72.8 bits (177), Expect = 2e-12
Identities = 54/184 (29%), Positives = 67/184 (36%), Gaps = 24/184 (13%)
Query: 707 CTCNQHGT---CDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQAD----DCQPCPCPG 759
C C+ H C C HHT GP CE C P P+ C PC C
Sbjct: 157 CQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQ 216
Query: 760 QSA-CTTIPESREV-------VCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQ 811
+ C E + VC C GR C C GF+ DP + C CQ
Sbjct: 217 HARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQ 276
Query: 812 CSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQ 871
C + G C+ SG C C TG C C G Y + +PR MPC P+
Sbjct: 277 C--HPIGATGGTCNQTSGQC-TCKLGVTGLTCNRCGPG-YQQSRSPR-----MPCQRIPE 327
Query: 872 GSVS 875
+ +
Sbjct: 328 ATTT 331
Score = 67.0 bits (162), Expect = 1e-10
Identities = 47/142 (33%), Positives = 60/142 (42%), Gaps = 25/142 (17%)
Query: 673 CSCPTGYTGQFCESCAPGYK----REMPQGGPYASCVPCTCNQHG-TCDPNT-------- 719
C C TG CESC P ++ R P+ C+PC+CNQH C N+
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHP-CLPCSCNQHARRCRFNSELFRLSGG 233
Query: 720 ---GICV-CSHHTEGPSCERCLPGFYGNP----FAGQADDCQPCPCPGQSACTTIPESRE 771
G+C C HHT G C C PGF+ +P F+ +A C+ C C A
Sbjct: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRA--CRACQCHPIGATGGTCNQTS 291
Query: 772 VVCTHCPPGQRGRRCEVCDDGF 793
CT C G G C C G+
Sbjct: 292 GQCT-CKLGVTGLTCNRCGPGY 312
Score = 38.5 bits (88), Expect = 0.052
Identities = 22/78 (28%), Positives = 32/78 (41%), Gaps = 6/78 (7%)
Query: 418 GFHSLSEGGCRP-CTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFN-----LQP 471
G L+ G R C C+ + R RC C+ + G C+ CRP + P
Sbjct: 144 GQAGLAAAGLRGRCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATP 203
Query: 472 HNPAGCSSCFCYGHSKVC 489
+P C C C H++ C
Sbjct: 204 RHPHPCLPCSCNQHARRC 221
>gi|54312078 netrin G1 isoform 3 [Homo sapiens]
Length = 438
Score = 152 bits (385), Expect = 2e-36
Identities = 114/346 (32%), Positives = 158/346 (45%), Gaps = 42/346 (12%)
Query: 53 TCGSPPEDFCPHVGAAGAGAHCQR-CDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFG 111
TCG PPE FC A G C CDA+ P+ H + DF + ST+WQS +
Sbjct: 71 TCGDPPETFC----AMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWK-- 124
Query: 112 VQYPT--SVNITLRLGKAYEIT-YVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQ 168
+YP VNITL K E+T + + F + RP+ + K W+PYQ+Y+ C
Sbjct: 125 -EYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCL 183
Query: 169 KTYGR-PEGQYLRPGEDERVAFCTSEFSDISPLSGGNVAFST-----------LEGRPSA 216
+ P+ CT E+S + + F L S
Sbjct: 184 DAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASL 243
Query: 217 YN-FEESPGLQEWVTSTELLISLDRLNTFGDDIFKDPKVLQSYYYAVSDFSVGGRCKCNG 275
Y + + L+++ T T+L I L L +IF D L Y+YA+SD V GRCKCN
Sbjct: 244 YGQLDTTKKLRDFFTVTDLRIRL--LRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNL 301
Query: 276 HASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGT-----AEAAHECLPCNCS 330
HA+ C D + +L C C+HNTTG DC +C +Q RPW+ G+ A+ C+P S
Sbjct: 302 HATVCVYDNS-KLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
Query: 331 GRSEECTFDRELFRSTGHGGRCHH-----CRDHTAGPHCE--RCQE 369
+ C D EL +GG CH+ C G CE RC+E
Sbjct: 361 IGTNVC--DNELLHCQ-NGGTCHNNVRCLCPAAYTGILCEKLRCEE 403
Score = 42.7 bits (99), Expect = 0.003
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 14/84 (16%)
Query: 707 CTCNQHGTC---DPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSAC 763
C CN H T D + C C H+T GP C +C + G P++ + P P +A
Sbjct: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGS----YLPIPKGTAN 352
Query: 764 TTIPESREV---VC----THCPPG 780
T IP + VC HC G
Sbjct: 353 TCIPSISSIGTNVCDNELLHCQNG 376
Score = 34.3 bits (77), Expect = 0.98
Identities = 26/114 (22%), Positives = 39/114 (34%), Gaps = 38/114 (33%)
Query: 327 CNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFY--HWDP-------- 376
C C+ + C +D C +T GP C +C++N+ W P
Sbjct: 297 CKCNLHATVCVYDNSKLTC--------ECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPK 348
Query: 377 --RMPCQP---------CD-----CQSAGSLHLQCDDTGTCACKPTVTGWKCDR 414
C P CD CQ+ G+ C + C C TG C++
Sbjct: 349 GTANTCIPSISSIGTNVCDNELLHCQNGGT----CHNNVRCLCPAAYTGILCEK 398
Score = 34.3 bits (77), Expect = 0.98
Identities = 30/109 (27%), Positives = 39/109 (35%), Gaps = 19/109 (17%)
Query: 834 CLHNTTGDHCEHCQEGFYGSALAP---RPADKCMPCSCHPQGSVSEQMPCDPVTGQC--- 887
C HNTTG C C++ + G +P P K +C P S CD C
Sbjct: 317 CEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDNELLHCQNG 376
Query: 888 -SCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQ 935
+C +V C Y G C +C GS C +GQ
Sbjct: 377 GTCHNNVRCL-CPAAYTGIL-------CEKLRCEEAGS----CGSDSGQ 413
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 146 bits (369), Expect = 1e-34
Identities = 122/418 (29%), Positives = 157/418 (37%), Gaps = 95/418 (22%)
Query: 673 CSCPTGYTGQFCES-CAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVCSHHTEGP 731
C C G+ G C S CAPG GP PC+C + +CDP +G+C C + P
Sbjct: 120 CQCVPGWRGDDCSSECAPG------MWGPQCD-KPCSCGNNSSCDPKSGVCSCPSGLQPP 172
Query: 732 SC-ERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESR-----EVVC----------- 774
+C + C PG+YG P C PC Q+ P R +V C
Sbjct: 173 NCLQPCTPGYYG-PACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPS 231
Query: 775 TH----------------CPPGQRGRRCEV-CDDGFFGDPLGLFGHPQPCHQCQCSGNVD 817
TH CPPG G C + C +GF G P +C+C
Sbjct: 232 THSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHG--------PNCSQECRCHNG-- 281
Query: 818 PNAVGNCDPLSGHCLRCLHNTTGDHC-EHCQEGFYGSALAPRPADKCMPCSCHPQGSVSE 876
G CD +G C RC TGD C E C G +G D C C P
Sbjct: 282 ----GLCDRFTGQC-RCAPGYTGDRCREECPVGRFGQ-------DCAETCDCAPDAR--- 326
Query: 877 QMPCDPVTGQCSCLPHVTARDCS--RCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTG 934
C P G C C T C+ C GF+ L C + H L CHP G
Sbjct: 327 ---CFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSL-----SCHPMNG 378
Query: 935 QCTCRPGVTGQAC-DRCQLGFFGFSIKGCRA-CRCSPLGAASAQCHENGTCVCRPGFEGY 992
+C+C PG G C + C G GC+ C C G A +G C C PG+ G
Sbjct: 379 ECSCLPGWAGLHCNESCPQDTHG---PGCQEHCLCLHGGVCQA---TSGLCQCAPGYTGP 432
Query: 993 KC-DRCHDNFFLTADGTHCQQCPSCYALVKEEAAKLKARLTLTEGWLQGSDCGSPWGP 1049
C C + + G +C SC + + + EGW +G +C P P
Sbjct: 433 HCASLCPPDTY----GVNCSARCSCENAI--ACSPIDGECVCKEGWQRG-NCSVPCPP 483
Score = 143 bits (360), Expect = 1e-33
Identities = 110/348 (31%), Positives = 136/348 (39%), Gaps = 60/348 (17%)
Query: 672 ICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVCSHHTEGP 731
+C C GYTG C S P P C+C C P G CVC +
Sbjct: 422 LCQCAPGYTGPHCASLCP------PDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRG 475
Query: 732 SCE-RCLPGFYGNPFAGQADDCQPCPC-PGQSACTTIPESREVVCT-HCPPGQRGRRCEV 788
+C C PG +G C P ACT P C CP GQ G C
Sbjct: 476 NCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCAS 535
Query: 789 ---CDDGFFGDPL--------GLFGH------PQPCHQCQCSGNVDPNAVGNCDPLSGHC 831
CD DP+ G G P+ CS G C P +G+C
Sbjct: 536 RCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNC 595
Query: 832 LRCLHNTTGDHCEH-CQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCL 890
+ C G C+ CQ G YG +C+PC C + C P G C CL
Sbjct: 596 V-CAPGFRGPSCQRSCQPGRYGK--------RCVPCKC------ANHSFCHPSNGTCYCL 640
Query: 891 PHVTARDCSR-CYPGFFDLQPGRGC-RSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQAC- 947
T DCS+ C PG + G C ++C+CH G+ CHP+ G C C G TG C
Sbjct: 641 AGWTGPDCSQPCPPGHW----GENCAQTCQCHHGGT----CHPQDGSCICPLGWTGHHCL 692
Query: 948 DRCQLGFFGFSIKGCRACRCSPLGAASAQCH-ENGTCVCRPGFEGYKC 994
+ C LG FG + + C+C P +CH E G CVC PG G C
Sbjct: 693 EGCPLGTFGANCS--QPCQCGP----GEKCHPETGACVCPPGHSGAPC 734
Score = 131 bits (330), Expect = 4e-30
Identities = 125/457 (27%), Positives = 158/457 (34%), Gaps = 130/457 (28%)
Query: 673 CSCPTGYTGQFCE-SCAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVCSHHTEGP 731
CSCP G+ G C C G+ GP S C C+ G CD TG C C+ G
Sbjct: 248 CSCPPGWMGTICSLPCPEGFH------GPNCS-QECRCHNGGLCDRFTGQCRCAPGYTGD 300
Query: 732 SC-ERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRC--EV 788
C E C G +G D + C C + C P + +C H G G RC +
Sbjct: 301 RCREECPVGRFGQ------DCAETCDCAPDARC--FPANGACLCEH---GFTGDRCTDRL 349
Query: 789 CDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHC-EHCQ 847
C DGF+G CQ D +C P++G C CL G HC E C
Sbjct: 350 CPDGFYG------------LSCQAPCTCDREHSLSCHPMNGEC-SCLPGWAGLHCNESCP 396
Query: 848 EGFYGSAL--------------------------APRPADKCMP----CSCHPQGSVSEQ 877
+ +G P A C P +C + S
Sbjct: 397 QDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENA 456
Query: 878 MPCDPVTGQCSCLPHVTARDCS-RCYPGFFDLQPGRGCR-SCKCHPLGSQEDQCHPKTGQ 935
+ C P+ G+C C +CS C PG + G C SC+C + E C P+TG
Sbjct: 457 IACSPIDGECVCKEGWQRGNCSVPCPPGTW----GFSCNASCQC----AHEAVCSPQTGA 508
Query: 936 CTCRPGVTGQACD-RCQLGFFGFSIKGCRA----------------CRCSPLGAASAQCH 978
CTC PG G C C G FG +GC + C+C G A+CH
Sbjct: 509 CTCTPGWHGAHCQLPCPKGQFG---EGCASRCDCDHSDGCDPVHGRCQCQ-AGWMGARCH 564
Query: 979 --------------------------ENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQ 1012
ENG CVC PGF G C R G + ++
Sbjct: 565 LSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRS------CQPGRYGKR 618
Query: 1013 CPSCYALVKEEAAKLKARLTLTEGWLQGSDCGSPWGP 1049
C C GW G DC P P
Sbjct: 619 CVPCKCANHSFCHPSNGTCYCLAGW-TGPDCSQPCPP 654
Score = 60.5 bits (145), Expect = 1e-08
Identities = 41/119 (34%), Positives = 51/119 (42%), Gaps = 22/119 (18%)
Query: 673 CSCPTGYTGQFC-ESCAPGYKREMPQGGPYASCVP-CTCNQHGTCDPNTGICVCSHHTEG 730
C C G+TG C + C PG+ E +C C C+ GTC P G C+C G
Sbjct: 637 CYCLAGWTGPDCSQPCPPGHWGE--------NCAQTCQCHHGGTCHPQDGSCICPLGWTG 688
Query: 731 PSC-ERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEV 788
C E C G +G A+ QPC C C PE+ VC PPG G C +
Sbjct: 689 HHCLEGCPLGTFG------ANCSQPCQCGPGEKCH--PETGACVC---PPGHSGAPCRI 736
Score = 59.3 bits (142), Expect = 3e-08
Identities = 59/244 (24%), Positives = 78/244 (31%), Gaps = 59/244 (24%)
Query: 270 RCKCNGHASECGPDVAGQLACR-----------CQHNTTGTDCER--------------- 303
RC C+ H+ C P V G+ C+ C G +C
Sbjct: 536 RCDCD-HSDGCDP-VHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENG 593
Query: 304 ---CLPFFQDRPWARGTAEAAH--ECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDH 358
C P F+ R + C+PC C+ S G C+ C
Sbjct: 594 NCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSF----------CHPSNGTCY-CLAG 642
Query: 359 TAGPHCER-CQENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLP 417
GP C + C HW Q C C G+ H Q G+C C GW CL
Sbjct: 643 WTGPDCSQPCPPG--HWGENC-AQTCQCHHGGTCHPQ---DGSCICP---LGWTGHHCLE 693
Query: 418 G--FHSLSEGGCRPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPA 475
G + +PC C P + C P +G C C G C F + P P
Sbjct: 694 GCPLGTFGANCSQPCQCGPG---EKCHPETGACVCPPGHSGAPCRIGIQEPFTVMPTTPV 750
Query: 476 GCSS 479
+S
Sbjct: 751 AYNS 754
Score = 56.2 bits (134), Expect = 2e-07
Identities = 64/252 (25%), Positives = 80/252 (31%), Gaps = 69/252 (27%)
Query: 268 GGRCKCNGHASECGPDVAG-QLACRCQHNTTGTDCER---------CLPFFQD----RPW 313
GG C+ +C P G A C +T G +C C P + W
Sbjct: 413 GGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGW 472
Query: 314 ARGTAEAAHECLP------CNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERC 367
RG C P CN S +C + TG C G HC+
Sbjct: 473 QRGNCSVP--CPPGTWGFSCNASC---QCAHEAVCSPQTG----ACTCTPGWHGAHCQ-- 521
Query: 368 QENFYHWDPRMPCQP----------CDCQSAGSLHLQCDDT-GTCACKPTVTGWKCDRCL 416
+PC CDC + CD G C C+ G +C
Sbjct: 522 ----------LPCPKGQFGEGCASRCDCDHSDG----CDPVHGRCQCQAGWMGARCHLSC 567
Query: 417 PGFHSLSEGGC-RPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDR-CRPGTFNLQPHNP 474
P L C CTC G TC P +G C C G C R C+PG + +
Sbjct: 568 P--EGLWGVNCSNTCTCKNGG---TCLPENGNCVCAPGFRGPSCQRSCQPGRYGKR---- 618
Query: 475 AGCSSCFCYGHS 486
C C C HS
Sbjct: 619 --CVPCKCANHS 628
Score = 53.9 bits (128), Expect = 1e-06
Identities = 53/209 (25%), Positives = 74/209 (35%), Gaps = 44/209 (21%)
Query: 846 CQEGFYGSA--LAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDC-SRCY 902
C GFY S P A +C+ C QC C+P DC S C
Sbjct: 90 CCHGFYESRGFCVPLCAQECVHGRC-------------VAPNQCQCVPGWRGDDCSSECA 136
Query: 903 PGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQAC-DRCQLGFFGFSIK- 960
PG + Q + C SC C PK+G C+C G+ C C G++G + +
Sbjct: 137 PGMWGPQCDKPC-SC------GNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQF 189
Query: 961 --GCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCYA 1018
C C P + G C C G CD + GT CPS ++
Sbjct: 190 RCQCHGAPCDP---------QTGACFCPAERTGPSCD------VSCSQGTSGFFCPSTHS 234
Query: 1019 LVKEEAAKL-KARLTLTEGWLQGSDCGSP 1046
+ + + GW+ G+ C P
Sbjct: 235 CQNGGVFQTPQGSCSCPPGWM-GTICSLP 262
Score = 53.1 bits (126), Expect = 2e-06
Identities = 71/291 (24%), Positives = 89/291 (30%), Gaps = 91/291 (31%)
Query: 279 ECGPDVA---GQLACRCQHNTTGTDC-ERCLP--FFQDRPWARGTAEAAHE--------- 323
+C PD AC C+H TG C +R P F+ A T + H
Sbjct: 320 DCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGE 379
Query: 324 --CLP------CNCS--------GRSEECTFDRELFRSTGHGGRCH------HCRDHTAG 361
CLP CN S G E C HGG C C G
Sbjct: 380 CSCLPGWAGLHCNESCPQDTHGPGCQEHCL--------CLHGGVCQATSGLCQCAPGYTG 431
Query: 362 PHCER-------------------------------CQENFYHWDPRMPCQPCDCQSAGS 390
PHC C+E + + +PC P + +
Sbjct: 432 PHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCN 491
Query: 391 LHLQC-------DDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCDP 443
QC TG C C P G C P EG C C+ + D CDP
Sbjct: 492 ASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPK-GQFGEGCASRCDCDHS---DGCDP 547
Query: 444 RSGRCPCKENVEGNLCD-RCRPGTFNLQPHNPAGC---SSCFCYGHSKVCA 490
GRC C+ G C C G + + N C +C + VCA
Sbjct: 548 VHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCA 598
Score = 51.2 bits (121), Expect = 8e-06
Identities = 63/233 (27%), Positives = 85/233 (36%), Gaps = 53/233 (22%)
Query: 270 RCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTA----EAAHECL 325
RC+C H + C P AC C TG C D ++GT+ + H C
Sbjct: 190 RCQC--HGAPCDPQTG---ACFCPAERTGPSC--------DVSCSQGTSGFFCPSTHSCQ 236
Query: 326 PCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCER-CQENFYHWDPRMPCQPCD 384
+ +F++ G C C G C C E F+ P Q C
Sbjct: 237 -------------NGGVFQTPQ--GSCS-CPPGWMGTICSLPCPEGFH--GPNCS-QECR 277
Query: 385 CQSAGSLHLQCDD-TGTCACKPTVTGWKC-DRCLPGFHSLSEGGCRPCTCNPAGSLDTCD 442
C + G CD TG C C P TG +C + C G + C C P C
Sbjct: 278 CHNGGL----CDRFTGQCRCAPGYTGDRCREECPVG--RFGQDCAETCDCAPDA---RCF 328
Query: 443 PRSGRCPCKENVEGNLC-DR-CRPGTFNLQPHNPAGCS---SCFCYGHSKVCA 490
P +G C C+ G+ C DR C G + L P C S C+ + C+
Sbjct: 329 PANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECS 381
Score = 42.4 bits (98), Expect = 0.004
Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 16/97 (16%)
Query: 374 WDPRMPCQPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKC-DRCLPGFHSLSEGGCR-PC 430
W P+ +PC C + S CD +G C+C + C C PG++ + C+ C
Sbjct: 140 WGPQCD-KPCSCGNNSS----CDPKSGVCSCPSGLQPPNCLQPCTPGYYGPA---CQFRC 191
Query: 431 TCNPAGSLDTCDPRSGRCPCKENVEGNLCD-RCRPGT 466
C+ A CDP++G C C G CD C GT
Sbjct: 192 QCHGA----PCDPQTGACFCPAERTGPSCDVSCSQGT 224
>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 145 bits (367), Expect = 2e-34
Identities = 84/224 (37%), Positives = 107/224 (47%), Gaps = 26/224 (11%)
Query: 685 ESCAPGYKREMPQGGPYASCVPCTCNQHGT-CDPNTGICV-CSHHTEGPSCERCLPGFYG 742
E C G+ + CVPC CN + C +G CV C +T G CE+CL G+ G
Sbjct: 65 EKCNAGFFHTLS-----GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
Query: 743 NPFAGQADDCQPCPCP----GQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPL 798
+ G CQPCPCP A + ++ V C C G CE C G++G+PL
Sbjct: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPL 178
Query: 799 GLFGHPQPCHQCQCSGNVDPNAV-GNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAP 857
L G C +C CSGN DPN + +CD ++G C CL NTTG CE C G+YG A
Sbjct: 179 -LIG--STCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA--- 232
Query: 858 RPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRC 901
R A C C+C PCD VTG+C C +C
Sbjct: 233 RIAKNCAVCNCGGG-------PCDSVTGECLEEGFEPPTGCDKC 269
Score = 119 bits (297), Expect = 3e-26
Identities = 193/862 (22%), Positives = 320/862 (37%), Gaps = 119/862 (13%)
Query: 750 DDCQPCPCPGQSAC--TTIPESRE--VVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQ 805
D+ P G SA PE+ E V PP E C+ GFF G
Sbjct: 29 DNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPA-----AEKCNAGFFHTLSG------ 77
Query: 806 PCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMP 865
C C C+GN + C SG+C+ C NTTG+HCE C +G+ G ++ P C P
Sbjct: 78 ECVPCDCNGNSN-----ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP-QFCQP 131
Query: 866 CSCHPQGSVSEQMPCDPVTG--QCSCLPHVTARDCSRCYPGFF--DLQPGRGCRSCKCHP 921
C C + C G +C C + +C RC PG++ L G C+ C C
Sbjct: 132 CPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCS- 190
Query: 922 LGSQE-----DQCHPKTGQC-TCRPGVTGQACDRCQLGFFGFS--IKGCRACRC--SPLG 971
G+ + + C TGQC C TG C+RC G++G + K C C C P
Sbjct: 191 -GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCD 249
Query: 972 AASAQCHENGTCVCRPGFE-GYKCDRC----HDNFFLTA----DGTHCQQCPSCYALVKE 1022
+ + +C E GFE CD+C D L A +G S A
Sbjct: 250 SVTGECLEE-------GFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHR 302
Query: 1023 EAAKLKARLTLTEGWLQGSDCGSPWGPLDILLGEAPRGDVYQGHHLL-----PGAREAFL 1077
++ A + L + L + + I E + L +R+ L
Sbjct: 303 HVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKGQL 362
Query: 1078 EQMMSLEGAVKAA---------REQLQRLNKGARCAQAGSQKTCTQLADLEAVLESSEEE 1128
Q S++ A+ R+++Q +N + + ++++ + + EE
Sbjct: 363 VQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEE 422
Query: 1129 ILHAAAILASLEIPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRALLASNTSY 1188
I E+ E + + L ++A + R H +T T + L N
Sbjct: 423 IRSRQPFFTQRELVDEEADEAYE---LLSQAESWQRLHNETRT-LFPVVLEQLDDYNAKL 478
Query: 1189 ALLWNLLEGRVALETQRDLEDRYQEVQAAQKALRTAVAEVLPEAESV-LATVQQVGADTA 1247
+ L L+ AL RD ED + A Q+ V + E V ++ + T
Sbjct: 479 SDLQEALD--QALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTT 536
Query: 1248 PYLALLASPGALPQKS--RAEDLGLKAKALEKTVASWQHMATEAARTLQTAAQATLRQTE 1305
P L L + S AE G K++ L+ +++ +++ + + AQ ++
Sbjct: 537 PRLTLSELDDIIKNASGIYAEIDGAKSE-LQVKLSNLSNLSHDLVQEAIDHAQDLQQEAN 595
Query: 1306 PLT-KLHQEARAALTQ---------------ASSSVQAATVTVMGARTLLADLEGMKLQF 1349
L+ KLH L Q S + + A + + + G+ Q
Sbjct: 596 ELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQI 655
Query: 1350 PRPKDQA--------ALQRKADSVSDRLLADTRKKTKQAERMLGNAAPLSSSAKKKGREA 1401
KD++ LQ KA+S SD +ADT R +G A S+ K +
Sbjct: 656 IYHKDESENLLNQARELQAKAESSSDEAVADT-------SRRVGGALARKSALKTR---- 704
Query: 1402 EVLAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQASQQVLASEARRQELEEAERVG 1461
D+ K +A R Q SRL ++ QQ A A
Sbjct: 705 ---LSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQH 761
Query: 1462 AGLSEMEQQIRESRISLEKDIETLSELLARLGSLDTHQAPAQALNETQWALERLRLQLGS 1521
S + +R ++ E + +LL +L +++ + PA ++ +++R+R +
Sbjct: 762 FDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVE-QKRPASNVSA---SIQRIRELIAQ 817
Query: 1522 PGSLQRKLSLLEQESQQQELQI 1543
S+ K+ + Q +++
Sbjct: 818 TRSVASKIQVSMMFDGQSAVEV 839
Score = 99.0 bits (245), Expect = 3e-20
Identities = 65/201 (32%), Positives = 85/201 (42%), Gaps = 42/201 (20%)
Query: 675 CPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTC------NQHGTCDPNTGI--CVCSH 726
C TG+ CE C GY + +G P C PC C N +C G C+C+
Sbjct: 101 CQRNTTGEHCEKCLDGYIGDSIRGAP-QFCQPCPCPLPHLANFAESCYRKNGAVRCICNE 159
Query: 727 HTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVV---CTHCPPGQRG 783
+ GP+CERC PG+YGNP C+ C C G S I E + V C +C G
Sbjct: 160 NYAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTG 218
Query: 784 RRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHC 843
+CE C G++GD + C C C G G CD ++G CL
Sbjct: 219 FKCERCAPGYYGDA----RIAKNCAVCNCGG-------GPCDSVTGECL----------- 256
Query: 844 EHCQEGFYGSALAPRPADKCM 864
+EGF P DKC+
Sbjct: 257 ---EEGFE----PPTGCDKCV 270
Score = 97.4 bits (241), Expect = 9e-20
Identities = 68/201 (33%), Positives = 91/201 (45%), Gaps = 22/201 (10%)
Query: 271 CKCNGHASECGPDVAGQLAC-RCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC 329
C CNG+++EC + G C CQ NTTG CE+CL D A C PC C
Sbjct: 82 CDCNGNSNEC---LDGSGYCVHCQRNTTGEHCEKCL----DGYIGDSIRGAPQFCQPCPC 134
Query: 330 SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRM---PCQPCDCQ 386
F +R G RC C ++ AGP+CERC +Y +P + C+ CDC
Sbjct: 135 P-LPHLANFAESCYRKNG-AVRC-ICNENYAGPNCERCAPGYY-GNPLLIGSTCKKCDCS 190
Query: 387 SAGSLHL---QCDD-TGTCA-CKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTC 441
+L CD+ TG C C TG+KC+RC PG++ + CN G C
Sbjct: 191 GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGG--PC 248
Query: 442 DPRSGRCPCKENVEGNLCDRC 462
D +G C + CD+C
Sbjct: 249 DSVTGECLEEGFEPPTGCDKC 269
Score = 93.2 bits (230), Expect = 2e-18
Identities = 56/179 (31%), Positives = 78/179 (43%), Gaps = 28/179 (15%)
Query: 323 ECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPR---MP 379
EC+PC+C+G S EC G C HC+ +T G HCE+C + + R
Sbjct: 78 ECVPCDCNGNSNECL---------DGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF 128
Query: 380 CQPCDC------QSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHS---LSEGGCRPC 430
CQPC C A S + + + C C G C+RC PG++ L C+ C
Sbjct: 129 CQPCPCPLPHLANFAESCYRK-NGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKC 187
Query: 431 TC----NPAGSLDTCDPRSGRC-PCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYG 484
C +P + CD +G+C C N G C+RC PG + C+ C C G
Sbjct: 188 DCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCGG 245
Score = 66.2 bits (160), Expect = 2e-10
Identities = 42/134 (31%), Positives = 58/134 (43%), Gaps = 17/134 (12%)
Query: 286 GQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRS 345
G + C C N G +CERC P + P G+ C C+CSG S+ +
Sbjct: 151 GAVRCICNENYAGPNCERCAPGYYGNPLLIGST-----CKKCDCSGNSDPNLIFEDCDEV 205
Query: 346 TGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--CQPCDCQSAGSLHLQCDD-TGTCA 402
T G+C +C +T G CERC +Y D R+ C C+C CD TG C
Sbjct: 206 T---GQCRNCLRNTTGFKCERCAPGYY-GDARIAKNCAVCNCGGG-----PCDSVTGECL 256
Query: 403 CKPTVTGWKCDRCL 416
+ CD+C+
Sbjct: 257 EEGFEPPTGCDKCV 270
Score = 64.3 bits (155), Expect = 9e-10
Identities = 38/98 (38%), Positives = 46/98 (46%), Gaps = 18/98 (18%)
Query: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPY---ASCVPCTCNQHG-------TCDPNTGIC 722
C C Y G CE CAPGY G P ++C C C+ + CD TG C
Sbjct: 155 CICNENYAGPNCERCAPGY-----YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQC 209
Query: 723 -VCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPG 759
C +T G CERC PG+YG+ A A +C C C G
Sbjct: 210 RNCLRNTTGFKCERCAPGYYGD--ARIAKNCAVCNCGG 245
Score = 43.1 bits (100), Expect = 0.002
Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 413 DRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSGRC-PCKENVEGNLCDRCRPGTFNLQP 471
++C GF G C PC CN G+ + C SG C C+ N G C++C G
Sbjct: 65 EKCNAGFFHTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 122
Query: 472 HN-PAGCSSCFC 482
P C C C
Sbjct: 123 RGAPQFCQPCPC 134
>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 145 bits (367), Expect = 2e-34
Identities = 84/224 (37%), Positives = 107/224 (47%), Gaps = 26/224 (11%)
Query: 685 ESCAPGYKREMPQGGPYASCVPCTCNQHGT-CDPNTGICV-CSHHTEGPSCERCLPGFYG 742
E C G+ + CVPC CN + C +G CV C +T G CE+CL G+ G
Sbjct: 65 EKCNAGFFHTLS-----GECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIG 119
Query: 743 NPFAGQADDCQPCPCP----GQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPL 798
+ G CQPCPCP A + ++ V C C G CE C G++G+PL
Sbjct: 120 DSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI-CNENYAGPNCERCAPGYYGNPL 178
Query: 799 GLFGHPQPCHQCQCSGNVDPNAV-GNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAP 857
L G C +C CSGN DPN + +CD ++G C CL NTTG CE C G+YG A
Sbjct: 179 -LIG--STCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA--- 232
Query: 858 RPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRC 901
R A C C+C PCD VTG+C C +C
Sbjct: 233 RIAKNCAVCNCGGG-------PCDSVTGECLEEGFEPPTGCDKC 269
Score = 119 bits (297), Expect = 3e-26
Identities = 193/862 (22%), Positives = 320/862 (37%), Gaps = 119/862 (13%)
Query: 750 DDCQPCPCPGQSAC--TTIPESRE--VVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQ 805
D+ P G SA PE+ E V PP E C+ GFF G
Sbjct: 29 DNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPA-----AEKCNAGFFHTLSG------ 77
Query: 806 PCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMP 865
C C C+GN + C SG+C+ C NTTG+HCE C +G+ G ++ P C P
Sbjct: 78 ECVPCDCNGNSN-----ECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP-QFCQP 131
Query: 866 CSCHPQGSVSEQMPCDPVTG--QCSCLPHVTARDCSRCYPGFF--DLQPGRGCRSCKCHP 921
C C + C G +C C + +C RC PG++ L G C+ C C
Sbjct: 132 CPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCS- 190
Query: 922 LGSQE-----DQCHPKTGQC-TCRPGVTGQACDRCQLGFFGFS--IKGCRACRC--SPLG 971
G+ + + C TGQC C TG C+RC G++G + K C C C P
Sbjct: 191 -GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCD 249
Query: 972 AASAQCHENGTCVCRPGFE-GYKCDRC----HDNFFLTA----DGTHCQQCPSCYALVKE 1022
+ + +C E GFE CD+C D L A +G S A
Sbjct: 250 SVTGECLEE-------GFEPPTGCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHR 302
Query: 1023 EAAKLKARLTLTEGWLQGSDCGSPWGPLDILLGEAPRGDVYQGHHLL-----PGAREAFL 1077
++ A + L + L + + I E + L +R+ L
Sbjct: 303 HVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKGQL 362
Query: 1078 EQMMSLEGAVKAA---------REQLQRLNKGARCAQAGSQKTCTQLADLEAVLESSEEE 1128
Q S++ A+ R+++Q +N + + ++++ + + EE
Sbjct: 363 VQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEE 422
Query: 1129 ILHAAAILASLEIPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRALLASNTSY 1188
I E+ E + + L ++A + R H +T T + L N
Sbjct: 423 IRSRQPFFTQRELVDEEADEAYE---LLSQAESWQRLHNETRT-LFPVVLEQLDDYNAKL 478
Query: 1189 ALLWNLLEGRVALETQRDLEDRYQEVQAAQKALRTAVAEVLPEAESV-LATVQQVGADTA 1247
+ L L+ AL RD ED + A Q+ V + E V ++ + T
Sbjct: 479 SDLQEALD--QALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTT 536
Query: 1248 PYLALLASPGALPQKS--RAEDLGLKAKALEKTVASWQHMATEAARTLQTAAQATLRQTE 1305
P L L + S AE G K++ L+ +++ +++ + + AQ ++
Sbjct: 537 PRLTLSELDDIIKNASGIYAEIDGAKSE-LQVKLSNLSNLSHDLVQEAIDHAQDLQQEAN 595
Query: 1306 PLT-KLHQEARAALTQ---------------ASSSVQAATVTVMGARTLLADLEGMKLQF 1349
L+ KLH L Q S + + A + + + G+ Q
Sbjct: 596 ELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQI 655
Query: 1350 PRPKDQA--------ALQRKADSVSDRLLADTRKKTKQAERMLGNAAPLSSSAKKKGREA 1401
KD++ LQ KA+S SD +ADT R +G A S+ K +
Sbjct: 656 IYHKDESENLLNQARELQAKAESSSDEAVADT-------SRRVGGALARKSALKTR---- 704
Query: 1402 EVLAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQASQQVLASEARRQELEEAERVG 1461
D+ K +A R Q SRL ++ QQ A A
Sbjct: 705 ---LSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQH 761
Query: 1462 AGLSEMEQQIRESRISLEKDIETLSELLARLGSLDTHQAPAQALNETQWALERLRLQLGS 1521
S + +R ++ E + +LL +L +++ + PA ++ +++R+R +
Sbjct: 762 FDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVE-QKRPASNVSA---SIQRIRELIAQ 817
Query: 1522 PGSLQRKLSLLEQESQQQELQI 1543
S+ K+ + Q +++
Sbjct: 818 TRSVASKIQVSMMFDGQSAVEV 839
Score = 99.0 bits (245), Expect = 3e-20
Identities = 65/201 (32%), Positives = 85/201 (42%), Gaps = 42/201 (20%)
Query: 675 CPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTC------NQHGTCDPNTGI--CVCSH 726
C TG+ CE C GY + +G P C PC C N +C G C+C+
Sbjct: 101 CQRNTTGEHCEKCLDGYIGDSIRGAP-QFCQPCPCPLPHLANFAESCYRKNGAVRCICNE 159
Query: 727 HTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVV---CTHCPPGQRG 783
+ GP+CERC PG+YGNP C+ C C G S I E + V C +C G
Sbjct: 160 NYAGPNCERCAPGYYGNPLL-IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTG 218
Query: 784 RRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHC 843
+CE C G++GD + C C C G G CD ++G CL
Sbjct: 219 FKCERCAPGYYGDA----RIAKNCAVCNCGG-------GPCDSVTGECL----------- 256
Query: 844 EHCQEGFYGSALAPRPADKCM 864
+EGF P DKC+
Sbjct: 257 ---EEGFE----PPTGCDKCV 270
Score = 97.4 bits (241), Expect = 9e-20
Identities = 68/201 (33%), Positives = 91/201 (45%), Gaps = 22/201 (10%)
Query: 271 CKCNGHASECGPDVAGQLAC-RCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC 329
C CNG+++EC + G C CQ NTTG CE+CL D A C PC C
Sbjct: 82 CDCNGNSNEC---LDGSGYCVHCQRNTTGEHCEKCL----DGYIGDSIRGAPQFCQPCPC 134
Query: 330 SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRM---PCQPCDCQ 386
F +R G RC C ++ AGP+CERC +Y +P + C+ CDC
Sbjct: 135 P-LPHLANFAESCYRKNG-AVRC-ICNENYAGPNCERCAPGYY-GNPLLIGSTCKKCDCS 190
Query: 387 SAGSLHL---QCDD-TGTCA-CKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTC 441
+L CD+ TG C C TG+KC+RC PG++ + CN G C
Sbjct: 191 GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGG--PC 248
Query: 442 DPRSGRCPCKENVEGNLCDRC 462
D +G C + CD+C
Sbjct: 249 DSVTGECLEEGFEPPTGCDKC 269
Score = 93.2 bits (230), Expect = 2e-18
Identities = 56/179 (31%), Positives = 78/179 (43%), Gaps = 28/179 (15%)
Query: 323 ECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPR---MP 379
EC+PC+C+G S EC G C HC+ +T G HCE+C + + R
Sbjct: 78 ECVPCDCNGNSNECL---------DGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQF 128
Query: 380 CQPCDC------QSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHS---LSEGGCRPC 430
CQPC C A S + + + C C G C+RC PG++ L C+ C
Sbjct: 129 CQPCPCPLPHLANFAESCYRK-NGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKC 187
Query: 431 TC----NPAGSLDTCDPRSGRC-PCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYG 484
C +P + CD +G+C C N G C+RC PG + C+ C C G
Sbjct: 188 DCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYG-DARIAKNCAVCNCGG 245
Score = 66.2 bits (160), Expect = 2e-10
Identities = 42/134 (31%), Positives = 58/134 (43%), Gaps = 17/134 (12%)
Query: 286 GQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRS 345
G + C C N G +CERC P + P G+ C C+CSG S+ +
Sbjct: 151 GAVRCICNENYAGPNCERCAPGYYGNPLLIGST-----CKKCDCSGNSDPNLIFEDCDEV 205
Query: 346 TGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP--CQPCDCQSAGSLHLQCDD-TGTCA 402
T G+C +C +T G CERC +Y D R+ C C+C CD TG C
Sbjct: 206 T---GQCRNCLRNTTGFKCERCAPGYY-GDARIAKNCAVCNCGGG-----PCDSVTGECL 256
Query: 403 CKPTVTGWKCDRCL 416
+ CD+C+
Sbjct: 257 EEGFEPPTGCDKCV 270
Score = 64.3 bits (155), Expect = 9e-10
Identities = 38/98 (38%), Positives = 46/98 (46%), Gaps = 18/98 (18%)
Query: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPY---ASCVPCTCNQHG-------TCDPNTGIC 722
C C Y G CE CAPGY G P ++C C C+ + CD TG C
Sbjct: 155 CICNENYAGPNCERCAPGY-----YGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQC 209
Query: 723 -VCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPG 759
C +T G CERC PG+YG+ A A +C C C G
Sbjct: 210 RNCLRNTTGFKCERCAPGYYGD--ARIAKNCAVCNCGG 245
Score = 43.1 bits (100), Expect = 0.002
Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 413 DRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSGRC-PCKENVEGNLCDRCRPGTFNLQP 471
++C GF G C PC CN G+ + C SG C C+ N G C++C G
Sbjct: 65 EKCNAGFFHTLSGECVPCDCN--GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 122
Query: 472 HN-PAGCSSCFC 482
P C C C
Sbjct: 123 RGAPQFCQPCPC 134
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,748,011
Number of Sequences: 37866
Number of extensions: 3984005
Number of successful extensions: 22265
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 121
Number of HSP's successfully gapped in prelim test: 727
Number of HSP's that attempted gapping in prelim test: 12444
Number of HSP's gapped (non-prelim): 4605
length of query: 1575
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1459
effective length of database: 13,855,062
effective search space: 20214535458
effective search space used: 20214535458
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.